WorldWideScience

Sample records for aging society aging

  1. The pedagogicalization of ageing societies

    DEFF Research Database (Denmark)

    Fristrup, Tine

    2011-01-01

    Transformations' in' the' age'profile'of' a'population' are' a' response' to' political' and' economic' structures' and' in' relation' to' public'services'older'people'become'a'burden'to'the'younger'work) ing'people.'The'construction'of'a'social'problem'in'relation'to'popu) lation' ageing' becomes......'way'of'controlling'the'processes'of'subjectification'in'old' age'as'the'socialization'of'an'ageing'person'in'relation'to'the'disci) plining' of' population' ageing:' becoming' a' subject' to' active' and' healthy'ageing.'The'future'of'ageing'societies'depends'on'the'plas) ticity' of' the' individual' performance' underlying' people’s' personal' responsibility......' a' social' pedagogical' problem' involving' a' focus' on' social' pedagogical' interventions' throughout' the' life' course.'In'order'to'shape'the'future'of'society,'the'perspective'on' ageing'and'old'age'has'shifted'from'being'a'determined'process'to' becoming' a'modifiable' process' focusing' on...

  2. Agglomeration processes in aging societies

    OpenAIRE

    Theresa Grafeneder-Weissteiner; Klaus Prettner

    2010-01-01

    This article investigates agglomeration processes in aging societies by introducing an overlapping generation structure into a New Economic Geography model. Whether higher economic integration leads to spatial concentration of economic activity crucially hinges on the economies' demographic properties. While population aging as represented by declining birth rates strengthens agglomeration processes, declining mortality rates weaken them. This is due to the fact that we allow for nonconstant ...

  3. [Ageing society and laboratory medicine].

    Science.gov (United States)

    Okabe, H

    2000-09-01

    An interest in the ageing process has increased greatly with increasing the population of the aged. The goal of this interest is to improve the quality of life(QOL) in the aged. In this paper, the presidential address "Ageing Society and Laboratory Medicine" at the 46th annual meeting of JSCP in Kumamoto'99 was summarized on the important research for ageing in the past decades. The paper presented was age- and gene-related changes, the latent variation of serum constituents and lipids abnormality in the ageing process. Concerning to the definition of reference value of healthy populations and the subjects who had no combined ailments, the reference interval of individuals(intra-personal), followed 5 years categorized by age, sex, and social conditions, gave a narrow range of variation than did a larger mixed populations(inter-personal). The reference intervals set would be a more sensitive reference than is the customary "normal range" for values occurring in inter-personal. Concerning to the study of the relationship between laboratory test and activity of daily living(ADL), the higher serum levels for TP, Alb, Hb, Glu, TC were observed in the higher ADL. The basic research techniques were also evaluated in the paper. The serum lipoperoxides were correlated with serum lipoprotein free radicals which caused atherosclerosis. The higher frequency of cerebral- and myocardial-infarction in the aged were observed in the higher serum LDL-C and lower serum level of arachidonic acid(AA), eicosapentaenoic acid(EPA), and AA/EPA ratio were observed in AMI patients with lower HDL-C groups than the healthy aged. Although Alzheimer(AD)'s disease had a progressive memory loss and immobile dementia and was reported the decrease of acetyltransferase activity in the brain, decrease of serum level of free choline, lyso-phosphatidylcholine, phosphatidylcholine(PC) and sphingomyelin(SM)/PC ratio were observed in spite of keeping normal serum level of SM. The decreased serum levels of

  4. Children in an ageing society.

    Science.gov (United States)

    Hall, D M

    1999-11-20

    This paper explores the implications of demographic aging for children and pediatric practice in the Western society. It focuses on the social class differences in childbearing patterns, specific issues related to disability, and distribution of resources between age groups. Women in the Western world are now having children at an older age than at any time in the past 50 years. Voluntary childlessness or deliberate delay in childbearing is common among highly educated women. This changing pattern in childbearing may increase and polarize health and wealth inequalities. With advancements in neonatal and pediatric care which prolong life expectancy and survival of disabled children, it is projected that there will be an increasing number of very old parents caring for severely disabled offspring. Meanwhile, there are also many children who are carrying considerable burdens of caring for their disabled parents. The community burden of disability will continue to rise. The needs of the elderly population may drain resources from child health services. Despite this demographic pattern, care for the children is still important. Health care authorities must not become contented with the existing pediatric care services just because demographic changes require that the nation should invest more in care of the older population. PMID:10567149

  5. Active Ageing in a Greying Society: Training for All Ages

    Science.gov (United States)

    Hessel, Roger

    2008-01-01

    With the ageing of society, policy-makers are aware of the need to retain older workers in employment. Across Europe, lifelong learning is increasingly important. Adults who remain active longer need (re-)training to maintain their productivity. However, vocational training tends to decline with age. The article analyses European employment policy…

  6. Sociological imagination for the aged society

    NARCIS (Netherlands)

    Ossewaarde, Marinus

    2014-01-01

    The aim of this article is to explore how the sociological imagination may generate new insights regarding the dangers and possibilities that arise when an old order disintegrates and a new one has to be created. The new order is theorized as the “aged society”. The aged society is demarcated by rad

  7. Introduction to Ageing: science, medicine, and society

    OpenAIRE

    Klug, A

    1997-01-01

    Introduction to Ageing: science, medicine, and society, the proceedings of a Discussion held at The Royal Society on 7 and 8 May 1997. Organized and edited by J. Grimley Evans, R. Holliday, T. B. L. Kirkwood, P. Laslett and L. Tyler.

  8. Assessment of Capacity in an Aging Society

    Science.gov (United States)

    Moye, Jennifer; Marson, Daniel C.; Edelstein, Barry

    2013-01-01

    Over the past 40 years, the assessment and scientific study of capacity in older adults has emerged as a distinct field of clinical and research activity for psychologists. This new field reflects the convergence of several trends: the aging of American society, the growing incidence and prevalence of dementia, and the patient rights,…

  9. Learning to Cope with an Ageing Society

    Science.gov (United States)

    McNair, Stephen

    2009-01-01

    The ageing of society is one of the biggest policy challenges of this time. Growing life expectancy and low birth rates mean that, for the fist time in human history, most people, and certainly the more prosperous social groups, will be spending a third of their lives in "retirement". This has profound social, cultural and economic implications,…

  10. On Population Kinetics of an Aging Society: Aging and Scurvy

    CERN Document Server

    Ely, J T A

    2006-01-01

    Evidence from skeletal remains and pictorial records for the past several millennia established that humans have had a very inadequate ascorbic acid intake and commonly exhibited signs of frank scurvy, as well as the invisible signs of subclinical scurvy (absence of AA in scorbutic urine is universal). They suffered scurvy's mortality, being a major cause of death especially in times of stress due to dietary fluctuations, climate, migrations, voyages, battles, etc. Rapid aging and death by acute scurvy, and infectious and degenerative diseases related to chronic scurvy added to the toll. In this era, the loss of function and changes in appearance that we see in humans in the second 50 years of life are theoretically simple to avoid. However, this is very rare because there is almost no one who does not eat the refined diet of the affluent societies. We present here an overview of a vast array of evidence on the connections between aging and scurvy.

  11. Failing ageing? Risk management in the active ageing society

    DEFF Research Database (Denmark)

    Rostgaard, Tine

    2015-01-01

    According to the European Commission's recent policy initiative on social investment, Danish Long term care offers new and innovative perspectives in ageing and the management of the risks associated thereof with the introduction of reablement (rehabilitering). From the perspective of governmenta...

  12. On Population Kinetics of an Aging Society: Aging and Scurvy

    OpenAIRE

    Ely, John T. A.

    2006-01-01

    Evidence from skeletal remains and pictorial records for the past several millennia established that humans have had a very inadequate ascorbic acid intake and commonly exhibited signs of frank scurvy, as well as the invisible signs of subclinical scurvy (absence of AA in scorbutic urine is universal). They suffered scurvy's mortality, being a major cause of death especially in times of stress due to dietary fluctuations, climate, migrations, voyages, battles, etc. Rapid aging and death by ac...

  13. Aging.

    Science.gov (United States)

    Park, Dong Choon; Yeo, Seung Geun

    2013-09-01

    Aging is initiated based on genetic and environmental factors that operate from the time of birth of organisms. Aging induces physiological phenomena such as reduction of cell counts, deterioration of tissue proteins, tissue atrophy, a decrease of the metabolic rate, reduction of body fluids, and calcium metabolism abnormalities, with final progression onto pathological aging. Despite the efforts from many researchers, the progression and the mechanisms of aging are not clearly understood yet. Therefore, the authors would like to introduce several theories which have gained attentions among the published theories up to date; genetic program theory, wear-and-tear theory, telomere theory, endocrine theory, DNA damage hypothesis, error catastrophe theory, the rate of living theory, mitochondrial theory, and free radical theory. Although there have been many studies that have tried to prevent aging and prolong life, here we introduce a couple of theories which have been proven more or less; food, exercise, and diet restriction. PMID:24653904

  14. Population Aging and Innovation Do Old Societies Think New Ideas?

    OpenAIRE

    Litina, Anastasia; Irmen, Andreas

    2014-01-01

    This research advances the hypothesis that at the individual level "old people think old ideas" whereas at the aggregate level "old societies think new ideas." More precisely, we empirically establish the following three hypotheses: i) population aging has a hump-shaped effect on innovation, ii) old societies think new ideas, and iii) the effect of population aging on innovation operates partly through a favorable attitude towards new ideas and creativity. Our results falsify the often encoun...

  15. Psychotherapy in the Internet age society

    OpenAIRE

    Wojciech Drath

    2015-01-01

    The article regards a number of challenges for psychotherapy, posed by the dynamic development of the Internet and changes in the functioning of individuals and societies this causes. The author analyses the social role of psychotherapy - its tasks, the needs it fulfils, and the expectations it tries to meet. Subsequently, he refers to cultural changes related to the communication revolution, and points at areas which will require special attention in the coming years, so that psychotherapist...

  16. Future mobility in an ageing society: Where are we heading?

    NARCIS (Netherlands)

    Shergold, I.; Lyons, G.; Hubers, C.

    2014-01-01

    The demographic profile of UK society is changing as people live longer. Maintaining the wellbeing and quality of life of an ageing society is set to be extremely challenging. To what extent can the state afford to meet a potentially burgeoning demand for social care? What expectations will be place

  17. Challenges of a Modern Atlas of the Ageing Society

    Science.gov (United States)

    Bleisch, S.; Hil, D.; Korkut, S.; Meyer, P.

    2016-06-01

    Atlases are collections of illustrated data, often maps, which give an overview - as well as some details - of one or several topic areas. We noted that this description serves well especially for traditional paper and digital atlases. However, in our today's world of entertainment it might give a somewhat dated impression. For the topic area 'Ageing Society' we aim to visualise age related data in an interactive digital way that supports not only the content but also engages the users, offers opportunities for different stakeholders and levels of interest, and is able to accommodate a range of data as well as future updates. A set of guiding principles for the development process addresses these challenges. First implementations show that following the principles is feasible but expensive in terms of time and attention to detail needed. For each selected topic, a story guides the users through the data and highlights interesting aspects. The user can interrupt the story at any time and explore the data further through interacting with the detailed data representations, and switch back to the story when needed. This allows different levels of access which in combination with the specifically designed navigation concept as well as through the adherence to user aware design principles are very promising for the future developments of the Atlas of the Ageing Society and potentially other atlas products.

  18. Gate-Keeping in the Age of Information Society

    DEFF Research Database (Denmark)

    Andersen, Kim Normann; Zinner Henriksen, Helle; Medaglia, Rony;

    Despite ten years of direct regulation, our study of Danish lower secondary schools shows that they do not provide online access to the GPA for individual public schools (N=1,592). Using Lipsky’s gate-keeping theory, we investigate the lack of data provision as indicator not only of professionals...... in the age of information society where expectations of end-of-gatekeeping by providing accessibility and transparency using information systems has been outnumbered by classical forces of gate-keeping....

  19. The global agenda council on the ageing society: policy principles

    DEFF Research Database (Denmark)

    Olshansky, S. Jay; Biggs, Simon; Achenbaum, W. Andrew;

    2011-01-01

    In 2008, the World Economic Forum (WEF) created the Global Agenda Councils – an amalgamation of scientists, public policy makers, academics, physicians and business leaders with the task of devising transformational innovation in global governance for the purpose of advancing knowledge and......, proposing solutions, devising strategies, making public policy proposals and evaluating the effectiveness of actions using measurable benchmarks. This report is the first product of the WEF’s Council on the Ageing Society – our goal is to lay down the initial principles that will guide our actions in the...

  20. Are societies with a high value on the Active Ageing Index more age-integrated?

    OpenAIRE

    Dykstra, Pearl; Fleischmann, Maria

    2016-01-01

    textabstractCombining round four data from the European Social Survey (ESS) with indicators of Active Ageing, we examine conditions conducive to age integration. We use both a behavioural and an attitudinal measure of age integration: the prevalence of cross-age friendships and low levels of ageism. The analyses focus on both “young” (age 18 to 30) and “old” (ages 70 to 90). Interestingly, high levels of independence, health and security in late life, and greater capacity to actively age rath...

  1. Towards an Analytical Age-Dependent Model of Contrast Sensitivity Functions for an Ageing Society

    Science.gov (United States)

    Joulan, Karine; Brémond, Roland

    2015-01-01

    The Contrast Sensitivity Function (CSF) describes how the visibility of a grating depends on the stimulus spatial frequency. Many published CSF data have demonstrated that contrast sensitivity declines with age. However, an age-dependent analytical model of the CSF is not available to date. In this paper, we propose such an analytical CSF model based on visual mechanisms, taking into account the age factor. To this end, we have extended an existing model from Barten (1999), taking into account the dependencies of this model's optical and physiological parameters on age. Age-dependent models of the cones and ganglion cells densities, the optical and neural MTF, and optical and neural noise are proposed, based on published data. The proposed age-dependent CSF is finally tested against available experimental data, with fair results. Such an age-dependent model may be beneficial when designing real-time age-dependent image coding and display applications. PMID:26078994

  2. Quality of Life in Ageing Societies: Italy, Portugal, and Turkey

    Science.gov (United States)

    Arun, Ozgur; Cevik, Aylin Cakiroglu

    2011-01-01

    The aim of this study was to compare and analyze the quality of life of the elderly in three aging countries: Italy, Portugal, and Turkey. This was done by using data provided by the European Quality of Life Survey completed in 2004. By doing so, we could then operationalize the conditions of the elderly in Turkey who have a rapid aging process…

  3. HOW COULD HOSPITALS ACT IN AN AGEING SOCIETY?

    Directory of Open Access Journals (Sweden)

    Leuca Mirela

    2011-12-01

    Full Text Available The demographic changes are of great importance for all European societies. Their impact and effects have multiple, deep facets. Each European healthcare and welfare system will be facing considerable changes in the new demographic context. The hospital sector plays an important role in each health system. This paper focuses on the impact of the demographic changes on hospitals, presents and analyzes statistical data for the German hospitals sector in order to underline the importance of the older age groups for the number of the hospital inpatient cases, the provided range of medical services and disciplines and for the hospital disease costs. The paper also reveals main findings from 30 interviews conducted in 2010 with German health experts (from hospitals, health insurance companies, universities, institutes and regional healthcare policy makers that accepted to answer questions referring to the demographic impact on the German healthcare system and hospital sector. The results of the interviews show that hospitals will have to act and react to the demographic changes. German hospitals might play different roles in the healthcare service provision for older people when engaging in new models of integrated care that will have to be developed. Processes, structures, human resources expertise, hospital service provision and medical departments will undergo major changes in response to the demographic challenges. Networks, centres of excellence for older persons and integrated care will probably be indispensable structures of the German healthcare system in the future. Strategic partnerships with pre- and post-hospital healthcare service providers are considered to be top priorities for German hospitals when facing the demographic challenge. Central case management and process optimization can be essential factors of success in the hospital care of the older, multimorbid patients. Acute geriatric medicine will be a main quality feature for the

  4. Japan: Super-Aging Society Preparing for the Future

    Science.gov (United States)

    Muramatsu, Naoko; Akiyama, Hiroko

    2011-01-01

    Japan has the highest proportion of older adults in the world. Aging is not only an immediate personal issue but also a salient factor in crucial public policies, such as pensions, health, and long-term care. The Great East Japan Earthquake, tsunami, and nuclear power plant disaster of March 2011 has highlighted current and emerging issues of a…

  5. Educating an Aging Society: The University of the Third Age in Finland.

    Science.gov (United States)

    Yenerall, Joseph D.

    2003-01-01

    The University of the Third Age in Finland has evolved from English and French models to include lectures, discussion groups, and research groups. A survey of 165 adult learners found their primary reason for participating was to acquire general education and self-knowledge. Socializing and meeting people were among the lowest ranked motivations.…

  6. Aging society and gerontechnology: a solution for an independent living?

    Science.gov (United States)

    Piau, A; Campo, E; Rumeau, P; Vellas, B; Nourhashémi, F

    2014-01-01

    Recent studies report that the majority of older adults wish to live in their own homes, for as long as possible. This creates a growing interest in technologies to enable older people to remain living independently at home. The purpose of this article is to provide a narrative review of current technology appropriate for older adults' home use. The key research questions were as follow: 1- What is the evidence demonstrating that gerontechnologies are effective in enabling independent living? 2- What are devices designed specifically for frail elderly persons ? Several publications were identified about devices targeting social isolation (videophonic communication, affective orthotic devices or companion-type robots, personal emergency response systems [security]), autonomy loss (technologies for maintenance of autonomy in the activities of daily living) and cognitive disorders (cognitive orthotics, wandering management systems, telemonitoring). Very few articles dealt specifically with the frail older person. In particular, there was extremely limited evidence on use and efficacy of these devices within this population. There is a need to obtain a consensus on definition of the technologies, and also to revisit work strategies and develop innovative business models. To meet this goal, we need to create a network of technological companies, aging services organizations, end-users, academics, and government representatives to explore the real needs of the frail older population and to develop and validate new devices promoting aging at home. PMID:24402399

  7. Is Soviet society fit for the nuclear age

    International Nuclear Information System (INIS)

    The author argues that the Kremlin's handling of the Chernobyl crisis is a far greater indictment of Soviet ethos, society and ideology than their technology. The Soviet nuclear plan is seen to be to press on regardless of safety standards. Australia's government and society, through poor education, foreign disinformation and media orchestration, are unable to participate effectively in the responsibilities of a global nuclear society

  8. Behavioral and emotional problems reported by parents of children ages 6 to 16 in 31 societies

    DEFF Research Database (Denmark)

    Rescorla, L.; Achenbach, T.; Ivanova, M.Y.;

    2007-01-01

    sizes for gender were ≤ .01, with girls generally scoring higher on Internalizing problems and boys generally scoring higher on Externalizing problems. Effect sizes for age were ≤ .01 and varied across types of problems. Total Problems scores for 19 of 31 societies were within 1 SD of the overall mean......This study compared parents' ratings of behavioral and emotional problems on the Child Behavior Checklist (Achenbach, 1991; Achenbach & Rescorla, 2001) for general population samples of children ages 6 to 16 from 31 societies (N = 55,508). Effect sizes for society ranged from .03 to .14. Effect...... of 22.5. Bisociety correlations for mean item scores averaged .74. The findings indicate that parents' reports of children's problems were similar in many ways across highly diverse societies. Nonetheless, effect sizes for society were larger than those for gender and age, indicating the need to take...

  9. HOW COULD HOSPITALS ACT IN AN AGEING SOCIETY?

    OpenAIRE

    Leuca Mirela

    2011-01-01

    The demographic changes are of great importance for all European societies. Their impact and effects have multiple, deep facets. Each European healthcare and welfare system will be facing considerable changes in the new demographic context. The hospital sector plays an important role in each health system. This paper focuses on the impact of the demographic changes on hospitals, presents and analyzes statistical data for the German hospitals sector in order to underline the importance of the ...

  10. Behavioral and Emotional Problems Reported by Parents of Children Ages 6 to 16 in 31 Societies

    Science.gov (United States)

    Rescorla, Leslie; Achenbach, Thomas; Ivanova, Masha Y.; Dumenci, Levent; Almqvist, Fredrik; Bilenberg, Niels; Bird, Hector; Chen, Wei; Dobrean, Anca; Dopfner, Manfred; Erol, Nese; Fombonne, Eric; Fonseca, Antonio; Frigerio, Alessandra; Grietens, Hans; Hannesdottir, Helga; Kanbayashi, Yasuko; Lambert, Michael; Larsson, Bo; Leung, Patrick; Liu, Xianchen; Minaei, Asghar; Mulatu, Mesfin S.; Novik, Torunn S.; Oh, Kyung-Ja; Roussos, Alexandra; Sawyer, Michael; Simsek, Zeynep; Steinhausen, Hans-Christoph; Weintraub, Sheila; Weisz, John; Metzke, Christa Winkler; Wolanczyk, Tomasz; Yang, Hao-Jan; Zilber, Nelly; Zukauskiene, Rita; Verhulst, Frank

    2007-01-01

    This study compared parents' ratings of behavioral and emotional problems on the "Child Behavior Checklist" (Achenbach, 1991; Achenbach & Rescorla, 2001) for general population samples of children ages 6 to 16 from 31 societies (N = 55,508). Effect sizes for society ranged from 0.03 to 0.14. Effect sizes for gender were less than or equal to 0.01,…

  11. Alluring Faces: Beauty Standards in Japanese Society through the Ages

    OpenAIRE

    Laufey Magnúsdóttir 1991

    2015-01-01

    This thesis discusses images of beauty in Japanese society; what the Japanese see as beautiful women and how those ideals have developed and what has been attempted d to achieve, from the early Heian period up until to our days. The thesis is split into three parts; first how ideals of beauty were presented during the Heian (794-1185) era, highlighting the aristocracy; and the Edo (1600-1868) era, with courtesans and geishas in the spotlight. The second part looks at the Meiji era (1868-1912)...

  12. Ageing Polulations

    DEFF Research Database (Denmark)

    Christiansen, Terkel; Lauridsen, Jørgen Trankjær; Bech, Mickael

    2013-01-01

    An ageing society is characterised by an increasing median age of the population. The purpose of this chapter is to document the existing knowledge about the association between population ageing and health care expenditure, and to supplement this overview by a summary of our original research. S...

  13. Population Aging

    OpenAIRE

    Weil, David N.

    2006-01-01

    Population aging is primarily the result of past declines in fertility, which produced a decades long period in which the ratio of dependents to working age adults was reduced. Rising old-age dependency in many countries represents the inevitable passing of this %u201Cdemographic dividend.%u201D Societies use three methods to transfer resources to people in dependent age groups: government, family, and personal saving. In developed countries, families are predominant in supporting children, w...

  14. Low carbon thermal technologies in an ageing society – What are the issues?

    International Nuclear Information System (INIS)

    This paper is a commentary on the theme of this special issue, low carbon thermal technologies and older age, and the Conditioning Demand project. Drawing on the project findings, I discuss some key aspects of ageing that are relevant to the roll-out of low carbon technologies in domestic settings in ageing, developed societies. These include biological, cognitive, institutional and social dimensions. I conclude with some suggestions for ways of working to maximise the potential benefits of low carbon thermal technologies for older people. -- Highlights: •The specific needs of older people must be considered in low carbon transitions. •The vulnerability discourse however dominates in a way which is unhelpful. •Some physiological aspects of ageing affect person-technology fit. •Cultural aspects influence the success of integration of LCTs into domestic settings. •More inclusive design is needed if older people are to benefit from LCTs

  15. Climate hazards, adaptation and "resilience" of societies (early Little Ice Age, west of France).

    Science.gov (United States)

    Athimon, Emmanuelle; Maanan, Mohamed

    2016-04-01

    Over the past ten to fifteen years, climate hazards and adaptation have received more attention due to the current climate change. Climate historians have gathered strong evidence that the world's climate has evolved over the past millennium and one of the most significant changes took place during the Little Ice Age. Recently, a set of questions has emerged: what were the effects of the Little Ice Age on human's societies? How did humans adapt to these climate changes? How did they react to extreme weather-related events? Using examples of climate hazards from the West of France during the beginning of the Little Ice Age (xivth-xviith centuries) such as storms, flooding, drought, harsh winters, the poster aims at showing how the past societies can constitute a source of inspiration for present ones. Through schemas, this research exposes the system's rebound capacity, points out the importance of the historical depth in research on human's adaptation and resilience and shows the value of integrating a historical approach. It reveals that History contributes to the knowledge of the relationship between societies and climate hazards. Data on climate hazards and adaptation of societies stem from historical sources such as chronicles, diaries, books of accounts, records of cities repairs. To protect themselves and their goods, medieval and modern societies had developed specific skills, practices and strategies. From the xivth to the xviiith century, there is an increase of defense by dikes in the low Loire, as for example the construction of those amongst Longué and Ponts-de-Cé between the early xivth century and 1407. The French kingdom's authorities also tried increasingly to provide technical, material, logistical and fiscal support: for instance, during the winter 1564-1565, several bridges have been destroyed by a river flooding in Nantes. The King Charles IX then offered to people of Nantes part of the funds from taxes on the main activities such as the

  16. ICT – An Agent of Change That Can Enrich a „Society of All Ages

    Directory of Open Access Journals (Sweden)

    Marilena IANCULESCU

    2008-12-01

    Full Text Available Demographic developments, including an aging population, change pathological models and pressures on health systems sustainability of the European Union. ICT can play a significant role in approaching these challenges because they allow the management and providing of health and social services more efficiently. Health informatics systems have the potential to play an important role in achieving well- being, independent living and delaying of the aging process and restoring the vitality of the mature body. The „Multidisciplinary Complex System for the Efficient Management of the Anti-Aging information (AgingNice” creates favourable conditions for the participation of all at the Information Society. AgingNice allows the sharing of the knowledge concerning the specific research and the promotion of the theoretical and practical information, both among the stakeholders from the medical area and at the citizen’s level. „Informational Centre of Dermatology (CID” is a complex system that has as target to achieve a modern informatics tool able to centralize in a single point a variety of web services and information classified by user’s type. Both health informatics systems demonstrate how ICT can improve the dissemination of health information, knowledge, comprising the users’ motivation concerning educational content and its new promoting methods.

  17. Home educating in an extended family culture and aging society may fare best during a pandemic.

    Directory of Open Access Journals (Sweden)

    Wayne Dawson

    Full Text Available Large cities can contain populations that move rapidly from one section to another in an efficient transportation network. An emerging air-borne or contact based pathogen could use these transportation routes to rapidly spread an infection throughout an entire population in a short time. Further, in many developed countries, the aging population is increasing. The family structure in these societies may also affect the course of a disease. To help understand the impact of an epidemic on family structure in a networked population, an individual based computer model that randomly generates networked cities with a specified range of population and disease characteristics and individual schedules, infectivity, transmission and hygiene factors was developed. Several salient issues emerged. First, a city of highly active individuals may in fact diminish the number of fatalities because the average duration of the interactions between agents is reduced. Second, home schooling can significantly improve survival because the institutional clustering of weak individuals is minimized. Third, the worst scenario for an aging population is the nuclear family where the aged population is confined to large housing facilities. Naturally, hygiene is the first barrier to infection. The results suggest that societies where extended families and small groups manage most of their own affairs may also be the most suitable for defense against a pandemic. This may prove applicable in city planning and policy making.

  18. Families and intergenerational relationships in aging societies: comparing the United States with German-speaking countries.

    Science.gov (United States)

    Bengtson, V L; Martin, P

    2001-06-01

    Industrialized nations have experienced many demographic changes favoring older adults during the last few decades of the 20th century. This article is a comparative examination of current and future trends in intergenerational relationships and aging in two societies: the United States and German-speaking countries. While comparing similarities and significant differences between the cultures, we examine five issues related to these trends for families and intergenerational relationships in the 21st century: (1) consequences of population aging for family structures and relationships--the emergence of the beanpole family structure and the longer years of linked lives across generations; (2) the debate about the decline of the family; (3) intergenerational solidarity over the life course; (4) intergenerational conflict across the life course; (5) prospects for solidarity and conflict between generations in the 21st century. Similarities between cultures include the demographic realities of population aging, the shift from pyramids to beanpoles, more years of shared lives between and across generations, more non-traditional family forms, and intergenerational conflicts in families. Differences include diverse replacement fertility rates, alternative approaches to governmental supports for families and aging members, and possible differences in cultural values regarding individualism. PMID:11487963

  19. Home care for an aging society: Why it’s needed; how it can be effective

    OpenAIRE

    Chappell, Neena

    2012-01-01

    This video clip comprises the IRPP Keynote Address: “Home care for an aging society: Why it’s needed; how it can be effective” held at the 21st Annual John K. Friesen Conference, "Innovations in Home Care: A Public Policy Perspective," MAY 16-17, 2012, Vancouver, BC. Presented by Neena Chappell, Professor, University of Victoria. It is well known that jurisdictions with more comprehensive and integrated home care delivery systems are able to extend independent living for older people ...

  20. Population aging in Albanian post-socialist society: Implications for care and family life

    Directory of Open Access Journals (Sweden)

    Meçe Merita

    2015-12-01

    Full Text Available Population aging is becoming an inevitable phenomenon in Albanian post-socialist society, posing multi-faceted challenges to its individuals, families and society as a whole. Since 1991, the Albanian population has been exposed to intensive demographic changes caused by unintended aspects of socio-economic transition from a planned socialist economy to a market-oriented capitalist one (Hoff, 2008. Ongoing processes of re-organization of social institutions increased its socio-economic insecurity leading to the application of various coping mechanisms. While adjusting themselves to other aspects of life, people changed their decisions of having children and leaving the country (Hoff, 2008. On the other hand, replacement of former traditional extended family forms with diverse living arrangements and family structures has been the outcome of the combination of three factors: falling fertility, increasing life expectancy and increasing migration (INSTAT, 2014.

  1. Age management

    OpenAIRE

    Kratochvilová, Markéta

    2014-01-01

    The Bachelor‘s thesis focuses on Age Management and its areas of influence. This term is most often discussed in connection with a problem which is currently common for all European Union countries – the ageing of society. In the near future, the structure of society is very likely to be altered drastically as a consequence of this phenomenon and due to the severity of the effects, it is necessary to begin addressing this problem. The first part of the thesis concerns itself with processing d...

  2. Aging Skin

    Science.gov (United States)

    ... email address Submit Home > Healthy Aging > Wellness Healthy Aging Aging skin More information on aging skin When it ... treated early. Return to top More information on Aging skin Read more from womenshealth.gov Varicose Veins ...

  3. Pension Systems and Pension Reform in an Aging Society. An Introduction to the Debate.

    OpenAIRE

    Baroni, Elisa

    2007-01-01

    Traditionally, pension systems aim to fulfill a number of functions which include income security and consumption smoothing in old age, as well as income redistribution. The main rationale for pension reform lies in the interaction between current demographic trends (e.g. increasing old age dependency ratios) and the design of existing pension systems (particularly, the so called Pay-As-You-Go public systems). Under certain conditions, population aging can in fact undermine the ability of a p...

  4. Coordination among industry, academic society and regulatory body in the research on aging management

    International Nuclear Information System (INIS)

    Many activities for the coordinated research on aging management are reviewed, and examples of fruitful results are introduced according to the technical strategy map. Industry-Academia-Government exchanging system of the information each other on aging management was established for autonomy, diversity, collaboration. To clarify the concept of the role of industry, government and academia to address aging management without duplication algorithm is for the overall coordination of industrial and academic information and response issues, technological strategy map for aging management formulated. (author)

  5. Dementia before death in ageing societies--the promise of prevention and the reality.

    Directory of Open Access Journals (Sweden)

    Carol Brayne

    2006-10-01

    Full Text Available BACKGROUND: Dementia and severe cognitive impairment are very closely linked to ageing. The longer we live the more likely we are to suffer from these conditions. Given population increases in longevity it is important to understand not only risk and protective factors for dementia and severe cognitive impairment at given ages but also whether protection affects cumulative risk. This can be explored by examining the effect on cumulative risk by time of death of factors found consistently to reduce risk at particular ages, such as education and social status. METHODS AND FINDINGS: In this analysis we report the prevalence of dementia and severe cognitive impairment in the year before death in a large population sample. In the Medical Research Council Cognitive Function and Ageing Study (a 10-y population-based cohort study of individuals 65 and over in England and Wales, these prevalences have been estimated by age, sex, social class, and education. Differences have been explored using logistic regression. The overall prevalence of dementia at death was 30%. There was a strong increasing trend for dementia with age from 6% for those aged 65-69 y at time of death to 58% for those aged 95 y and above at time of death. Higher prevalences were seen for severe cognitive impairment, with similar patterns. People with higher education and social class had significantly reduced dementia and severe cognitive impairment before death, but the absolute difference was small (under 10%. CONCLUSIONS: Reducing risk for dementia at a given age will lead to further extension of life, thus cumulative risk (even in populations at lower risk for given ages remains high. Ageing of populations is likely to result in an increase in the number of people dying with dementia and severe cognitive impairment even in the presence of preventative programmes. Policy development and research for dementia must address the needs of individuals who will continue to experience these

  6. From Zoomers to Geezerade: Representations of the Aging Body in Ageist and Consumerist Society

    Directory of Open Access Journals (Sweden)

    Suzanne Dupuis-Blanchard

    2013-01-01

    Full Text Available This paper is based on an analysis of representations of seniors in the media. In particular, we examine images of the bodies of seniors in the advertising campaigns promoting a product called Geezerade sold in Circle K convenience stores in the Atlantic provinces of Canada in the summer of 2011. We contrast these with images of seniors in the Canadian magazine Zoomer, formally CARP magazine, a magazine published by the Canadian Association of Retired People, a seniors advocacy organization. Following Goffman’s arguments in his seminal presidential address to the American Sociological Association, “the Interaction Order”, we take the position in this analysis that the body does not determine social practices but none-the-less the body is the sign vesicle that enables interaction. Concomitant however, while the images of bodies we see in the media do not determine the signs given and given off via bodily presentation, they none-the-less provide us with the categories by which we interpret those signs. We conclude that the images in the Geezerade campaign and Zoomer magazine represent a binary model of images of seniors that reflects ageist and classist assumptions about the bodies of seniors. Such a model limits the categories through which we understand the aging body and fails to account for the diversity of seniors’ bodies in society.

  7. Gendering fibulae: animals and gender roles in Iberian Iron Age societies

    Directory of Open Access Journals (Sweden)

    Consuelo MATA

    2013-06-01

    Full Text Available Since ancient times, domestic and wild animals have been an integral part of human life as food for survival, as transportation and as icons on the construction of the cultural imagery. Iberian culture during the Iron Age depicted such animals in ceramics, stone and terracotta sculpture, metals objects, and coins. These “imaginary” remains and the “real” faunal assemblages of settlements, necropoleis, and cultic places both reflect the ongoing relationships between human societies and other living things in the same environment –in this case the southeast area of the Iberian Peninsula. In this paper we analyze animal depictions in Iberian fibulae (brooches as a means from which to approach gender as a cultural construct. These fibulae were made in precious metals and decorated with hunting scenes or individual animals. They should be considered objects of special significance in specific social groups and elites wielding power among the Iberians. Studying contexts and comparing similar images that appear in other media with documented faunal assemblages provides us insights into Iberian social status, the gender of the wearer, and the meaning of certain animals.

  8. A report on older-age bipolar disorder from the International Society for Bipolar Disorders Task Force

    DEFF Research Database (Denmark)

    Sajatovic, Martha; Strejilevich, Sergio A; Gildengers, Ariel G;

    2015-01-01

    OBJECTIVES: In the coming generation, older adults with bipolar disorder (BD) will increase in absolute numbers as well as proportion of the general population. This is the first report of the International Society for Bipolar Disorder (ISBD) Task Force on Older-Age Bipolar Disorder (OABD). METHODS...

  9. Technical and Vocational Education and Training in an Ageing Society. Experts Meeting Proceedings (Adelaide, Australia, October 3-4, 2006)

    Science.gov (United States)

    Karmel, Tom, Ed.; Maclean, Rupert, Ed.

    2007-01-01

    One of the most striking features of the modern world is its changing demographic profile. In almost any policy arena, the issue of demographic change (or ageing) sits alongside globalisation, climate change and the knowledge revolution as areas which are transforming societies, including the ways in which we organise and go about our work…

  10. From Duty to Right: The Role of Public Education in the Transition to Aging Societies

    OpenAIRE

    Sugimoto, Yoshiaki; Nakagawa, Masao

    2009-01-01

    This paper argues that currently advanced, aging economies experienced a qualitative change in the role of public education during the process of industrialization. In the early phases of the Industrial Revolution, public education was regarded as a duty that regulated child labor and thereby discouraged childbirth. As these economies developed and the population aged, younger generations came to view public education as a right, whereas older generations desirous of other public services bec...

  11. Rural Aging

    Science.gov (United States)

    ... Rural Health > Topics & States > Topics View more Rural Aging The nation's population is aging, and with that change comes increased healthcare needs. ... Disease Control and Prevention report, The State of Aging and Health in America 2013 , the population 65 ...

  12. Lifestyle Modifications Versus Antihypertensive Medications in Reducing Cardiovascular Events in an Aging Society: A Success Rate-oriented Simulation.

    Science.gov (United States)

    Ohno, Yoichi; Shibazaki, Satomi; Araki, Ryuichiro; Miyazaki, Takashi; Sato, Makiko; Takahashi, Sachiko; Suwa, Emi; Takenaka, Tsuneo; Suzuki, Hiromichi

    2016-01-01

    Objective It is difficult to compare directly the practical effects of lifestyle modifications and antihypertensive medications on reducing cardiovascular disease (CVD). The purpose of this study was to compare the hypothetical potential of lifestyle modifications with that of antihypertensive medications in reducing CVD in an aging society using a success rate-oriented simulation. Methods We constructed a simulation model for virtual Japanese subpopulations according to sex and age at 10-year intervals from 40 years of age as an example of an aging society. The fractional incidence rate of CVD was calculated as the product of the incidence rate at each systolic blood pressure (SBP) level and the proportion of the SBP frequency distribution in the fractional subpopulations of each SBP. The total incidence rate was calculated by the definite integral of the fractional incidence rate at each SBP level in the sex- and age-specific subpopulations. Results If we consider the effects of lifestyle modifications on metabolic factors and transfer them onto SBP, the reductions in the total incidence rate of CVD were competitive between lifestyle modifications and antihypertensive medications in realistic scenarios. In middle-aged women, the preventive effects of both approaches were limited due to a low incidence rate. In middle-aged men and extremely elderly subjects whose adherence to antihypertensive medications is predicted to be low, lifestyle modifications could be an alternative choice. Conclusion The success rate-oriented simulation suggests that the effectiveness of lifestyle modifications or antihypertensive medications in preventing cardiovascular events largely depends on the baseline incidence rate and sex- and age-specific behavioral factors. PMID:27522993

  13. SOCIAL ECONOMY AND ACTIVE AGEING, AN INTEGRATED RESPONSE TO THE CHALLENGES OF MODERN SOCIETY

    Directory of Open Access Journals (Sweden)

    Aura-Mihaela Alexandrescu

    2012-05-01

    Full Text Available The article tackles population ageing, a demographic phenomenon registering a rapid growth over the last decades in the modern world, including Romania, viewed here from the perspective of the efforts undertaken by countries to find solutions to curb its negative impact on social life.Conceptually, these solutions can be defined by the active ageing phrase and are operationally integrated in the social economy system, representing the focus of the present article which also includes the views of renowned scientific authorities. The world economic crisis and massive layoffs called for an evaluation of the efficiency of those active measures advocating for the professional insertion of the elderly. We recall here the decision taken by the European Union leadership to declare 2012 as “The European Year for Active Ageing and Solidarity between Generations”.The interest in the field of social economy has increased due both to “acknowledging the limits of traditional public and private sectors in responding to today’s labour market challenges, and to the quality and quantity of the collective interest services” (European Parliament, Report on social economy”, 2009, p. 15. In light of this, understanding and capitalizing on the potential of social economy is essential and one of the solutions which appears to be most frequently mentioned. The article also covers the trends in population ageing and social implications, as well as various European and global initiatives whose results support the conclusion that developing social economy represents, indeed, one of the main solutions, so far underexploited, to the ageing challenge, providing substance to the concept of active ageing.

  14. Population Aging in the European Information Societies: Towards a Comprehensive Research Agenda in eHealth Innovations for Elderly.

    Science.gov (United States)

    Vancea, Mihaela; Solé-Casals, Jordi

    2016-08-01

    Population ageing is one of the major social and economic challenges of our contemporary societies. With the advent of the information society, new research and technological developments have been promoted in the field of assistive technologies and information and communication technologies of benefit to elderly people. This article examines the potentialities of new informatics developments in generating solutions to better address elderly people's daily-life, especially those with chronic illness and/or low autonomy. The authours attempt to propose a research agenda, by exposing various strengts and weaknesses of eHealth innovations for elderly, mainly grounded in secondary sources analysis. PMID:27493837

  15. Abandonment of agglomerations in late Iron Age in Central Europe - complex society facing complex problems

    Czech Academy of Sciences Publication Activity Database

    Danielisová, Alžběta; Cimler, R.; Olševičová, K.

    2013. [Annual Meeting of the European Association of Archaeologists /19./. 04.09.2013-08.09.2013, Plzeň] R&D Projects: GA ČR GAP405/12/0926 Institutional support: RVO:67985912 Keywords : collapse * oppida * late Iron Age Subject RIV: AC - Archeology, Anthropology, Ethnology

  16. Arterial Ageing

    OpenAIRE

    Lee, Seung-Jun; Park, Sung-Ha

    2013-01-01

    Arterial ageing is characterized by age associated degeneration and sclerosis of the media layer of the large arteries. However, besides ageing, clinical conditions, which enhance oxidative stress and inflammation act to accelerate the degree of arterial ageing. In this review, we summarized the pathophysiology and contributing factors that accelerate arterial ageing. Among them, we focused on hypertension, the renin-angiotensin-aldosterone system and vascular inflammation which are modifiabl...

  17. Pioneering farmers cultivating new lands in the North – The expansion of agrarian societies during the Neolithic and Bronze Age in Scandinavia

    DEFF Research Database (Denmark)

    Sørensen, Lasse

    2012-01-01

    Pioneering farmers cultivating new lands in the North – The expansion of agrarian societies during the Neolithic and Bronze Age in Scandinavia......Pioneering farmers cultivating new lands in the North – The expansion of agrarian societies during the Neolithic and Bronze Age in Scandinavia...

  18. Aging and demographic change in European societies : main trends and alternative policy options

    OpenAIRE

    Muenz, Rainer

    2007-01-01

    This paper gives an overview on current demographic trends and projected population change in Europe and neighboring regions. The main focus of the analysis is on Western and Central Europe. Today this world region has a total population of 500 million. Available forecasts until the year 2050 project a decline of the population at working age, a subsequent decline of the (native) work force and aparallel increase in the number of retired people. The paper discusses policy options by demonstra...

  19. Teaching in the Knowledge Society: Education in the Age of Insecurity.

    Science.gov (United States)

    Hargreaves, Andy

    This book discusses challenges facing teachers in the knowledge society today, focusing on the changing world and the changing work of teaching. Seven chapters discuss: (1) "Teaching for the Knowledge Society: Educating for Ingenuity" (e.g., profiting from, developing, and teaching for the knowledge society); (2) "Teaching Beyond the Knowledge…

  20. Skin Aging

    Science.gov (United States)

    ... too. Sunlight is a major cause of skin aging. You can protect yourself by staying out of ... person has smoked. Many products claim to revitalize aging skin or reduce wrinkles, but the Food and ...

  1. Aging mechanisms

    OpenAIRE

    Takahashi, Yoshiko; Kuro-o, Makoto; Ishikawa, Fuyuki

    2000-01-01

    Aging (senescence) has long been a difficult issue to be experimentally analyzed because of stochastic processes, which contrast with the programmed events during early development. However, we have recently started to learn the molecular mechanisms that control aging. Studies of the mutant mouse, klotho, showing premature aging, raise a possibility that mammals have an “anti-aging hormone.” A decrease of cell proliferation ability caused by the telomeres is also t...

  2. Happy Aging

    Institute of Scientific and Technical Information of China (English)

    梁秉中

    2009-01-01

    Aging is a normal physiological process in human life.The decline in the ability to repair and regenerate predisposes the aging person to develop disabling problems in the cardiovascular and skeletal systems.Full awareness of aging problems and advocations on the means to prevent their occurrence are mounting.European and US groups rely on scientific,target-oriented means to treat aging manifestations. Oriental medicine aims at prevention,using nutrition and exercise to maintain internal harmony.

  3. Creative Aging.

    Science.gov (United States)

    Ager, Charlene Lee; And Others

    1981-01-01

    Explores some divergent attitudes toward aging, negative as well as positive. Presents a neurophysiological framework to support the belief that aging is an active and creative process. Explores physical, psychological, and sociological aspects, and identifies three factors in the creative aging process. (Author/JAC)

  4. Skin Aging

    Science.gov (United States)

    Your skin changes as you age. You might notice wrinkles, age spots and dryness. Your skin also becomes thinner and loses fat, making it ... heal, too. Sunlight is a major cause of skin aging. You can protect yourself by staying out ...

  5. Do aging societies reduce intergenerational justice and increase pro-elderly policy bias?

    DEFF Research Database (Denmark)

    Vanhuysse, Pieter

    2015-01-01

    Wide across the Western world, people are living longer lives and having fewer children. This has led to larger shares of elderly voters, who, many fear, are becoming an immensely powerful political pressure group. But what are the effects of population aging on public policy? This article reviews...... the state of the art in comparative political science and social policy. Adopting a political lens provides insights that are more theoretically refined than the increasingly shrill and alarmist assertions being voiced recently about ‘gerontocratic’ welfare states dominated by unholy baby boomer...

  6. Gender roles and social policy in an ageing society: the case of Japan

    Directory of Open Access Journals (Sweden)

    Meiko Makita

    2010-10-01

    Full Text Available This article reviews the major underpinnings of the Japanese welfare state in the context of social care from a feminist perspective. In Japan, familycare responsibilities have traditionally been assigned to women; hence, care has long been a women’s issue. However, as the social contract of a male breadwinner and a “professional housewife” gradually fades out, Japanese women find more opportunities to renegotiate their caring roles. Of course, this social transformation did not occur in isolation, it was influenced by patterns in economic development, state policies and mainly demographic changes. All this has stimulated new state responses in the form of social welfare expansion that arguably aim to relieve women of the burdens of family-care. The issue remains, however, as to whether Japan would be able to recognise that the main structural issues of population ageing do not originate from demographic changes, but from a strict gendered division of labour and gender inequality.

  7. Longevity and health expectancy in an ageing society: implications for public health in Italy

    Directory of Open Access Journals (Sweden)

    Marianna Noale

    2012-01-01

    Full Text Available INTRODUCTION: While the prolongation of life expectancy is due to medical, economic, social and public health advancements, longevity may not necessarily be an indicator of real development. Epidemiologic data indicate, in fact, that advanced age carries the risk of multiple diseases, disability and loss of autonomy. MATERIALS AND METHODS: How the years gained are lived need to be assessed evaluating quality of life, health status, and disability. RESULTS AND CONCLUSIONS: Good health care planning should aim to ensure that the years of life gained are lived in good health conditions in the light of the World Health Organization's declaration that "increased longevity without quality of life is an empty prize. Health expectancy is more important than life expectancy".

  8. Civil society: the catalyst for ensuring health in the age of sustainable development

    OpenAIRE

    Smith, Julia; Buse, Kent; Gordon, Case

    2016-01-01

    Sustainable Development Goal Three is rightly ambitious, but achieving it will require doing global health differently. Among other things, progressive civil society organisations will need to be recognised and supported as vital partners in achieving the necessary transformations. We argue, using illustrative examples, that a robust civil society can fulfill eight essential global health functions. These include producing compelling moral arguments for action, building coalitions beyond the ...

  9. Successful ageing

    DEFF Research Database (Denmark)

    Kusumastuti, Sasmita; Derks, Marloes G M; Tellier, Siri;

    2016-01-01

    curvilinear pattern with the lowest point at middle age but increases thereafter up to very old age. OBJECTIVE: To shed further light on this paradox, we reviewed the existing literature on how scholars define successful ageing and how they weigh the contribution of health and functioning to define success....... METHODS: We performed a novel, hypothesis-free and quantitative analysis of citation networks exploring the literature on successful ageing that exists in the Web of Science Core Collection Database using the CitNetExplorer software. Outcomes were visualized using timeline-based citation patterns. The......BACKGROUND: Ageing is accompanied by an increased risk of disease and a loss of functioning on several bodily and mental domains and some argue that maintaining health and functioning is essential for a successful old age. Paradoxically, studies have shown that overall wellbeing follows a...

  10. Skin aging:

    OpenAIRE

    Puizina-Ivić, Neira

    2008-01-01

    There are two main processes that induce skin aging: intrinsic and extrinsic. A stochastic process that implies random cell damage as a result of mutations during metabolic processes due to the production of free radicals is also implicated. Extrinsic aging is caused by environmental factors such as sun exposure, air pollution, smoking, alcohol abuse, and poor nutrition. Intrinsicaging reflects the genetic background and depends on time. Various expressions of intrinsic aging include smooth, ...

  11. Changes in the carbon footprint of Japanese households in an aging society.

    Science.gov (United States)

    Shigetomi, Yosuke; Nansai, Keisuke; Kagawa, Shigemi; Tohno, Susumu

    2014-06-01

    As the aging and low birthrate trends continue in Japan, and as changes in the working population and consumption patterns occur, new factors are expected to have an impact on consumption-based greenhouse gas (GHG) emissions. We present the impacts of changes in the composition of Japanese households on GHG emission structures using current (2005) consumption-based accounting on the commodity sectors that are expected to require priority efforts for reducing emissions in 2035. This is done using the Global Link Input-Output model (GLIO) and domestic household consumption data and assuming that recent detailed consumption expenditures based on the Social Accounting Matrix (SAM) will continue into the future. The results show that consumption-based GHG emissions derived from Japanese household consumption in 2035 are estimated to be 1061 Mt-CO2eq (4.2% lower than in 2005). This study can be used to reveal more information and as a resource in developing policies to more meticulously and efficiently reduce emissions based on emission and import rates for each domestic and overseas commodity supply chain. PMID:24798825

  12. Matte Svart Kristiansen & Kate Giles (eds., Dwellings, Identities and Homes. European Housing Culture from the Viking Age to the Renaissance (Hojbjerg: Jutland Archeological Society, 2014

    Directory of Open Access Journals (Sweden)

    Thomas Hoeren

    2016-03-01

    Full Text Available Book review of: Matte Svart Kristiansen & Kate Giles (eds., Dwellings, Identities and Homes. European Housing Culture from the Viking Age to the Renaissance (Hojbjerg: Jutland Archeological Society, 2014

  13. Civil society: the catalyst for ensuring health in the age of sustainable development.

    Science.gov (United States)

    Smith, Julia; Buse, Kent; Gordon, Case

    2016-01-01

    Sustainable Development Goal Three is rightly ambitious, but achieving it will require doing global health differently. Among other things, progressive civil society organisations will need to be recognised and supported as vital partners in achieving the necessary transformations. We argue, using illustrative examples, that a robust civil society can fulfill eight essential global health functions. These include producing compelling moral arguments for action, building coalitions beyond the health sector, introducing novel policy alternatives, enhancing the legitimacy of global health initiatives and institutions, strengthening systems for health, enhancing accountability systems, mitigating the commercial determinants of health and ensuring rights-based approaches. Given that civil society activism has catalyzed tremendous progress in global health, there is a need to invest in and support it as a global public good to ensure that the 2030 Agenda for Sustainable Development can be realised. PMID:27424031

  14. Ageing management

    International Nuclear Information System (INIS)

    Ageing management is generally defined in a broad sense covering not only ageing management of hardware (structures, systems and components), but also management issues such as keeping up with developments in state-of-the-art technology and the latest management practices. The importance assigned to traditional ageing management, in terms of issues related to hardware degradation problems, is clearly very high. The other aspects, for example developments in engineering or management, are considered important as well, but are less emphasized. Plant ageing management is composed of the following necessary elements, which are all linked together: understanding and knowledge of ageing-related damage mechanisms, including benchmarking of the consequences of damage mechanisms into macroscopic behaviour of materials and structures under applicable conditions; predictive models to extrapolate behaviour of systems, structures or components up to a defined time; qualified methods for detection and surveillance of ageing degradation; qualified mitigation, repair and replacements measures; reliable plant documentation, including optimisation of the ageing management programme based on current understanding and knowledge and periodic self-assessment; availability of a technical service and knowledge base. The subject of plant ageing management has gained increasing attention over the past years, notably as more nuclear power plants across the world are being considered for lifetime extension. In this context, the NEA has conducted numerous technical studies to assess the impact of ageing mechanisms on safe and reliable plant operation. International research activities have also been initiated or are under way to provide the technical basis for decision making. This article provides an overview of some of the activities and accomplishments of the NEA Committee on the Safety of Nuclear Installations (CSNI) Working Group on the Integrity and Ageing of Components and Structures

  15. Preschool Psychopathology Reported by Parents in 23 Societies: Testing the Seven-Syndrome Model of the Child Behavior Checklist for Ages 1.5-5

    Science.gov (United States)

    Ivanova, Masha Y.; Achenbach, Thomas M.; Rescorla, Leslie A.; Harder, Valerie S.; Ang, Rebecca P.; Bilenberg, Niels; Bjarnadottir, Gudrun; Capron, Christiane; De Pauw, Sarah S. W.; Dias, Pedro; Dobrean, Anca; Doepfner, Manfred; Duyme, Michele; Eapen, Valsamma; Erol, Nese; Esmaeili, Elaheh Mohammad; Ezpeleta, Lourdes; Frigerio, Alessandra; Goncalves, Miguel M.; Gudmundsson, Halldor S.; Jeng, Suh-Fang; Jetishi, Pranvera; Jusiene, Roma; Kim, Young-Ah; Kristensen, Solvejg; Lecannelier, Felipe; Leung, Patrick W. L.; Liu, Jianghong; Montirosso, Rosario; Oh, Kyung Ja; Plueck, Julia; Pomalima, Rolando; Shahini, Mimoza; Silva, Jaime R.; Simsek, Zynep; Sourander, Andre; Valverde, Jose; Van Leeuwen, Karla G.; Woo, Bernardine S. C.; Wu, Yen-Tzu; Zubrick, Stephen R.; Verhulst, Frank C.

    2010-01-01

    Objective: To test the fit of a seven-syndrome model to ratings of preschoolers' problems by parents in very diverse societies. Method: Parents of 19,106 children 18 to 71 months of age from 23 societies in Asia, Australasia, Europe, the Middle East, and South America completed the Child Behavior Checklist for Ages 1.5-5 (CBCL/1.5-5). Confirmatory…

  16. The Shibboleth of Productivity: The Exhaustion of Industrial-Age Strategies in Post-Industrial Society

    OpenAIRE

    James E. Block

    1985-01-01

    The universal demand currently to resolve America's economic decline by increasing productivity fatally misconstrues the actual challenge posed by post-industrial society. Automation, rationalization, and technological advances suggest a crisis not of productivity, but of distribution, a false, unnecessary perpetuation of widespread deprivation required only by the scarcity model underpinning market economics. While enforced by vested interests for personal gain, this pseudo-crisis is ironica...

  17. Prevalence of premature ejaculation in young and middle-aged men in Korea: a multicenter internet-based survey from the Korean Andrological Society

    OpenAIRE

    Park, Hyun Jun; Park, Jong Kwan; Park, Kwangsung; Lee, Sung Won; Kim, Sae-Woong; Yang, Dae Yul; Moon, Du Geon; Min, Kweon-Sik; Moon, Ki-Hak; Yang, Sang-Kuk; Hyun, Jae Seog; Park, Nam Cheol

    2010-01-01

    In this study, we aimed to investigate the prevalence and perception of premature ejaculation (PE) in young and middle-aged Korean men. The study was conducted using an Internet-assisted questionnaire. A total of 2 037 Korean male adults, aged 20 years or older, were randomly sampled based on age and residency. The questionnaire developed by the PE Study Group of the Korean Andrological Society includes four categories (overall sexual function, symptoms, distress and treatment) with a total o...

  18. Healthy Ageing

    OpenAIRE

    Schans, Cees van der

    2015-01-01

    Presentatie gehouden bij de bijeenkomst voor het Regionaal Genootschap Fysiotherapie Het Noorden op 10 februari te Marum, over het belang van fysieke activiteit voor healthy ageing en de rol van de fysiotherapeut hierin

  19. Visual Signs of Ageing

    Directory of Open Access Journals (Sweden)

    Helle Rexbye

    2007-07-01

    Full Text Available Consumer culture has placed the ageing body in a dilemma of representation. Physical appearance has become increasingly important as a symbol of identity, and at the same time society idealizes youth. This study explores visual ageing empirically. By using photographs of older persons (70+ as starting point, it is explored how visual age is assessed and interpreted. It is shown that informants read age in a spread of stages and categories. Main age indicators are biological markers: skin, eyes, and hair colour, but supplemented by vigour, style, and grooming. Furthermore, in-depth interviews indicate that visual age is mainly interpreted into categories and moral regulations rooted in early modernity. Subsequently the question of a postmodern perspective of visual ageing is discussed in this article. The empirical findings in the study question a postmodern fluidity of visual signs – at least when the concern is signs of ageing.

  20. Biodemography of human ageing

    DEFF Research Database (Denmark)

    Vaupel, James W

    2010-01-01

    Human senescence has been delayed by a decade. This finding, documented in 1994 and bolstered since, is a fundamental discovery about the biology of human ageing, and one with profound implications for individuals, society and the economy. Remarkably, the rate of deterioration with age seems to be...

  1. Aging, Trade, and Migration

    OpenAIRE

    Chisik, Richard; Onder, Harun; Qirjo, Dhimitri

    2016-01-01

    This study considers the role of demand-driven changes arising from population aging and how they affect the pattern of international trade as well as trade and immigration policy. An aging society can see a welfare-reducing reduction in its share of manufacturing output and this reduction is magnified by a decrease in trade costs (an increase in globalization). Immigration can ameliorate ...

  2. A Respectable Old Age.

    Science.gov (United States)

    Swensen, Clifford H.

    1983-01-01

    Contrasts the relatively abundant information on the young with the paucity of research knowledge on the aged, and asserts that psychologists have too few solutions to coping with the problems of aging. Suggests the integration of older adults into all aspects of society through structural change. (Author/AOS)

  3. Aging and cosmetic enhancement

    OpenAIRE

    Honigman, Roberta; David J. Castle

    2006-01-01

    Obsession with a youthful appearance has become commonplace in modern society and has resulted in an upswing in cosmetic procedures trying to reverse the aging process. We selectively review the literature on aging and cosmetic surgery, with particular regard for the aging face. We pay attention to psychosocial aspects of response to such cosmetic procedures, both in terms of outcome and with respect to risk factors for a poor outcome.

  4. Martian ages

    International Nuclear Information System (INIS)

    The subjects of this paper are a discussion of the methodology of relative age determination by impact crater statistics, a comparison of currently proposed Martian impact chronologies for the determination of absolute ages from crater frequencies, a report on our work of dating Martian volcanoes and erosional features by impact crater statistics, and an attempt to understand the main features of Martian history through a synthesis of our crater frequency data and those published by other authors. Two cratering chronology models are presented and used for inference of absolute ages from crater frequency data: model 1, with nearly equal Martian and lunar cratering rates around (ca.) 4- to 10-km crater sizes, and model II. equivalent to model I for ages >3.5 x 109 years but with a factor of 2 higher Martian cratering rate at ages 9 years. Those model cratering chronologies are applied to the data. The interpretation of all crater frequency data available and tractable by our methodology leads to a global Martian geological history that is characterized essentially by two epochs of activity. The division between the two epochs is measured at a cumulative crater frequency value for 1-km craters (crater retention age) of N(1) = 8 x 10-4 (km-2) corresponding to an absolute age of ca. 3 x 109 years (applying model I cratering chronology) and of ca. 1.5 x 109 years (applying model II cratering chronology). In the ancient epoch all major events like emplacement of the plains lavas, the piling up of most volcanic constructs, and large-scale erosion of channels and mensae (highland/northern lowland boundary) have taken place. During the younger epoch, only the big Tharsis shield volcanoes were active, and some minor erosion took place. This means that Mars is not a youthful planet but an ancient one with respect to most of its surface features

  5. Premature aging

    International Nuclear Information System (INIS)

    The hypothesis that radiation may accelerate aging phenomenon has been studied extensively, using the population of A-bomb survivors. In this paper, non-specific radiation-induced premature aging is discussed with a review of the literature. Cardiac lipofuscin, papillary fibrosis, aortic extensibility, hexamine/collagen ratio in the skin and aorta, testicular changes, giant hepatic cell nucleus, and neurofibril changes have so far been studied pathologically in the context of A-bomb radiation. Only testicular sclerosis has been found to correlate with distance from the hypocenter. Suggestive correlation was found to exist between the hexamine/collagen ratio in the skin and aorta and A-bomb radiation. Grip strength and hearing ability were decreased in the group of 100 rad and the group of 50-99 rad, respectively. The other physiological data did not definitely correlate with A-bomb radiation. Laboratory data, including erythrocyte sedimentation rate, α and β globulin levels, phytohemagglutinin reaction, T cell counts, erythrocyte glycophorin-A, the incidence of cerebral stroke, ischemic heart disease, and cataract were age-dependent and correlated with A-bomb radiation. These findings indicated that the occurrence of arteriosclerosis-related diseases, changes in immunological competence, and some pathological and physiological findings altered with advancing age, suggesting the correlation with A-bomb radiation. In general, it cannot be concluded that there is a positive correlation between A-bomb radiation and the premature aging. (N.K.) 51 refs

  6. Successful ageing

    DEFF Research Database (Denmark)

    Bülow, Morten Hillgaard; Söderqvist, Thomas

    2014-01-01

    prevention strategies; and the importance of individual, societal and scientific conceptualisations and understandings of ageing. By presenting an account of the recent historical uses, interpretations and critiques of the concept, the article unfolds the practical and normative complexities of ‘ successful......Since the late 1980s, the concept of ‘ successful ageing’ has set the frame for discourse about contemporary ageing research. Through an analysis of the reception to John W. Rowe and Robert L. Kahn's launch of the concept of ‘ successful ageing’ in 1987, this article maps out the important themes...

  7. Aging Differently

    DEFF Research Database (Denmark)

    Zajitschek, Felix; Jin, Tuo; Colchero, Fernando;

    2014-01-01

    Diet effects on age-dependent mortality patterns are well documented in a large number of animal species, but studies that look at the effects of nutrient availability on late-life mortality plateaus are lacking. Here, we focus on the effect of dietary protein content (low, intermediate, and high...... statistical approach based on Bayesian inference of age-specific mortality rates and found a deceleration of late-life mortality rates on all diets in males but only on the intermediate (standard) diet in females. The difference in mortality rate deceleration between males and females on extreme diets...

  8. Age Spots

    Science.gov (United States)

    ... for treating age spots include: Improved appearance. Enhanced self-esteem. Promotion of better skin health. What you need ... 480px View Render 320px View Connect with ASDS: Facebook LinkedIn YouTube Twitter Quick Links About ASDS Advocacy ...

  9. Environmental Changes and Social Vulnerability in an Ageing Society: Portugal in the Transition from the 20th to the 21st Centuries

    Directory of Open Access Journals (Sweden)

    Maria João Guardado Moreira

    2010-11-01

    Full Text Available One of the main structural changes human societies are actually facing relies on demographic ageing process, with strong impacts on health system and quality of life. Social and environmental factors can be used as predictors for health conditions, functional and cognitive autonomy, wellbeing and satisfaction on older ages. Reduced incomes, low educational level, situation of loneliness, can also be pointed as predictive factors of a major and premature deterioration of health. The adaptation of social structures must be a priority for all ageing societies. Portugal will also have to find answers to these challenges. The main objective of this study is to understand the process of vulnerability and multiple dependency situations caused by changes in the Portuguese demographic structure, manly regarding old people, as concerns the following aspects: a levels of well-being in ageing regions determined by a statistical indicator; b specific health care and long-term care.

  10. Après Nous le Déluge? Direct Democracy and Intergenerational Conflicts in Ageing Societies

    OpenAIRE

    Ahlfeldt, Gabriel; Maennig, Wolfgang; Steenbeck, Malte

    2016-01-01

    To assess the likely effects of population ageing on the outcomes of direct democracy, we analyze the effect of age on voting decisions in public referenda. To this end, we provide the first quantitative review of the literature and a case study of the Stuttgart 21 referendum on one of the largest infrastructure projects in Germany. The evi-dence suggests that intergenerational conflicts arising from population ageing will likely be limited to areas in which the net present value differs part...

  11. Healthy ageing

    DEFF Research Database (Denmark)

    Harrison, Adrian Paul; Brüggemann, Dagmar Adeline; Bartels, Else Marie;

    2009-01-01

    The study employed mechanical stretching in vitro of sections of abdominal aorta of elderly mice to investigate any benefits of oral treatment with alpha-ketoglutarate (AKG) on arterial elasticity. Eighteen female mice (50-weeks-old) were assigned to a control (2% w/v) Na2-AKG or (2% w/v) a Ca-AK...... investigation as a candidate for therapies targeting arterial stiffening with age....

  12. Aging Perspectives

    OpenAIRE

    Cosco, Theodore D; David Brehme; Nora Grigoruta; Lisa-Katrin Kaufmann; Liis Lemsalu; Ruth Meex; Angela Schuurmans; Neslihan Sener

    2014-01-01

    Despite the proliferation of successful ageing (SA) research, the literature is dominated by researcher-driven Anglophone conceptualisations. To date, lay perspectives of SA have not been examined in Europe or Turkey. The current study aims to conduct a mixed-methods examination of conceptualisations of SA in seven underrepresented countries. Using snowball sampling via social media sites, an online survey consisting of established closed-ended and open-ended items – translated into seven lan...

  13. Golden Age

    Institute of Scientific and Technical Information of China (English)

    2013-01-01

      Sometimes, a moment can announce the end of an age. The gold market is like that. Within two transaction days, the gold slumped by 13%and saw a 25%tumble from the high point in August 2011. According to the classic investment theory, a 20%-above decline means the shift from“a bull”to“a bear”market.   The super bear market of gold has lasted a dozen years. But the bull-to-bear shift was completed within only 20 minutes. Wall Street’s analysts and ordinary Chinese people had different understandings to the golden age.   Expecting a bear market, Wall Street continuously dumped gold, resulting in a diving of gold price. Seeing the benefits, leisure Chinese madams made a gold rush, causing a slight bounce of gold price. On April 23, renowned investment bank Goldman Sachs suspended the short sale. So,“Chinese aunts”beating back Wall Street’s analysts became the hottest topic online for the time being.   What are the decisive factors for the crash of gold price? Will the gold market complete a real bull-to-bear shift? Will the golden age of gold be farther or nearer?

  14. New concept of age(ing: Prospective age

    Directory of Open Access Journals (Sweden)

    Devedžić Mirjana

    2012-01-01

    Full Text Available While the last century was the century of world population growth, according to demographers, the XXI century will be century of population aging. Statistics undoubtedly show that number of elderly will continue it’s growth in the future. If old age is seen as period of life with reduced physical and mental capabilities and increased disability, and demographic aging as increase of dependent population, trends are quite disturbing, at least in certain societal segments. In developed countries, this population category is no longer treated as passive or as a "burden of society" and efforts are made for better social inclusion of older people. In contrast to growing interest in this phenomenon, the concepts that define the aging of the population remained stagnant. The aim of this paper is to introduce into domestic literature the term "prospective age" as a dynamic category which is more affected with socio-historical conditions, not only with biological as traditional definition of aging suggested. Papers written by Sanderson and Scherbov offer new methodological options for study of population aging, because it takes into account the biometric rather than chronological approach. Calculation of prospective years is a simple operation that requires pair of the same number of remained life expectancy from life tables for two different periods (the year of concern is index, and the one we are comparing with is standard year, so that phrase "40s is the new 30s" or "70s the new 60s" gets scientific foundation. Average remaining years of life represent a realistic indicator suggesting increased capacity, activity and vitality of individuals, which is due to accepted demographic parameters still considered old. „Prospective threshold“ is defined as the age when life expectancy falls below 15 years (it is subjective choice made by Sanderson and Scherbov, which is also used in this paper and during the elaboration of these ideas three demographic

  15. Aging Perspectives

    Directory of Open Access Journals (Sweden)

    Theodore D Cosco

    2014-05-01

    Full Text Available Despite the proliferation of successful ageing (SA research, the literature is dominated by researcher-driven Anglophone conceptualisations. To date, lay perspectives of SA have not been examined in Europe or Turkey. The current study aims to conduct a mixed-methods examination of conceptualisations of SA in seven underrepresented countries. Using snowball sampling via social media sites, an online survey consisting of established closed-ended and open-ended items – translated into seven languages – was administered. Grounded theory methods and descriptive statistics were used to analyse qualitative and quantitative data, respectively.

  16. Ice ages

    International Nuclear Information System (INIS)

    The Earth's climate undergoes great changes in cycles of 104 to 105 years. Deep sea sediments contain proof of these changes. The critical parameter is the O18/O16 isotope ratio. The astronomical theory is discussed of ice ages based on the changes in the shape of the Earth's orbit around the sun. Forecasts for the future are given - in the coming years the climate is expected to get warmer owing to increased CO2 levels in the atmosphere, and then a long cooler period is expected to follow. (M.D.)

  17. Dominant perceptions on the age

    OpenAIRE

    Komatina Slavica

    2003-01-01

    Contemporary developed society, despite the fact that it is constantly and intensively ageing, is characterized by deeply rooted numerous negative stereotypes on old people and old age as a life period. The study of dominant perceptions on the age of Belgrade population takes not only the universal character of negative connotation of old age into consideration, but also the concrete unfavorable social context. The delicate problematic of stereotypes on old age and old people has been analyze...

  18. Aging Blepharoplasty

    Directory of Open Access Journals (Sweden)

    Inchang Cho

    2013-09-01

    Full Text Available In performing upper blepharoplasty in the elderly, looking younger and keeping the eyelidsharmonious with the rest of the face have to be achieved at the same time. The most importantgoal in upper blepharoplasty for aging is correcting the drooping upper eyelid skin, and inthis process, the surgeon may or may not create a double eyelid fold. The pros and cons haveto be fully discussed with the patient, but the author personally prefers creating a doublefold unless the patient refuses, because it is efficient in correcting and preventing furtherdrooping of the skin. In most patients, the brow is elevated to compensate for the droopingeyelid, and when the drooping is corrected, brow ptosis may ensue. The surgeon has to preparefor these consequences before performing the procedure, and estimate the exact amountof skin to be excised. In the elderly, the skin and the orbicularis oculi muscle is thin, with adecreased amount of subcutaneous fat and retro-orbicularis oculi fat, and in most cases,excision of the skin alone is enough to correct the deformity. Removing large portions ofsoft tissue may also prolong the recovery period. Unlike younger patients, the lower skinflap should not be stretched too much in the elderly, as it may create an aggressive lookingappearance. A few wrinkles in the lower flap should remain untouched to create a naturallook. In this article, the author’s own methods of performing an aging blepharoplasty aredescribed specifically, with a step-by-step guide and surgical tips.

  19. Unmaking old age : political and cognitive formats of active ageing.

    OpenAIRE

    Lassen, A.J.; Moreira, T.

    2014-01-01

    Active ageing is a policy tool that dominates the way the ageing society has been constituted during the last decades. The authors argue that active ageing is an attempt at unmaking the concept of old age, by engaging in the plasticity of ageing in various ways. Through a document study of the different epistemes, models and forms used in the constitution of active ageing policies, the authors show how active ageing is not one coordinated set of policy instruments, but comes in different form...

  20. Changing Attitudes towards Ageing and the Aged amongst Psychology Students

    Science.gov (United States)

    Fonseca, Antonio; Goncalves, Daniela; Martin, Ignacio

    2009-01-01

    Society is ageing. In Europe, the ageing of the population is a recurrent and discussed theme. The impact of the ageing of the population is varied and transversal in different fields. The increase in the number of elderly people implies an increase in the levels of dependence and, consequently, more sanitary, physical, and human resources. Also,…

  1. 当代纽约:从人口老龄化到老年友好型城市的转变%Modern New York:From Aging Society to Age-Friendly City

    Institute of Scientific and Technical Information of China (English)

    李胜

    2015-01-01

    纽约作为美国标志性城市,是公认的金融、传媒、文化及国际大都市。自1950年前后进入老龄化社会以来,该市老年人口在经济状况、族裔构成、地域分布、健康状况等方面表现出与全美相似但又独具特色的特征。在人口老龄化背景下,纽约经济、政治、社会各个方面均产生程度不一的影响。为了更好地应对这一挑战,纽约最终走向老年友好型城市的发展道路。%As one iconic city of United States and all over the world,New York City is always described as the financial,medi-a,cultural and international center. Around the 1950s,New York City became one aging society,part of whose characters of aging are coincident with those of American society. However,this city has some distinguishing features. Without doubt,aging population puts crucial and deep influences on New York City from all dimensions. In order to effectively address this chal-lenge,New York City moves towards one Age-Friendly city from the aging society.

  2. Aging blepharoplasty.

    Science.gov (United States)

    Cho, Inchang

    2013-09-01

    In performing upper blepharoplasty in the elderly, looking younger and keeping the eyelids harmonious with the rest of the face have to be achieved at the same time. The most important goal in upper blepharoplasty for aging is correcting the drooping upper eyelid skin, and in this process, the surgeon may or may not create a double eyelid fold. The pros and cons have to be fully discussed with the patient, but the author personally prefers creating a double fold unless the patient refuses, because it is efficient in correcting and preventing further drooping of the skin. In most patients, the brow is elevated to compensate for the drooping eyelid, and when the drooping is corrected, brow ptosis may ensue. The surgeon has to prepare for these consequences before performing the procedure, and estimate the exact amount of skin to be excised. In the elderly, the skin and the orbicularis oculi muscle is thin, with a decreased amount of subcutaneous fat and retro-orbicularis oculi fat, and in most cases, excision of the skin alone is enough to correct the deformity. Removing large portions of soft tissue may also prolong the recovery period. Unlike younger patients, the lower skin flap should not be stretched too much in the elderly, as it may create an aggressive looking appearance. A few wrinkles in the lower flap should remain untouched to create a natural look. In this article, the author's own methods of performing an aging blepharoplasty are described specifically, with a step-by-step guide and surgical tips. PMID:24086798

  3. PACITA: Scenario workshop “Teleassistance in ageing societies” (Spring-Summer 2014): Telecare Technology for an Ageing Society in Europe: Current State and Future Developments

    OpenAIRE

    PACITA Consortium (Hrsg.)

    2015-01-01

    PACITA (Parliaments and civil society in Technology Assessment) has been a four-year EU financed project under FP7 aimed at increasing the capacity and enhancing the institutional foundation for knowledge-based policy-making on issues involving science, technology and innovation, mainly based upon the diversity of practices in Parliamentary Technology Assessment (PTA). The key practices in focus have been interactive in the sense that they engaged science, civil society organizations, stakeho...

  4. Nexus: Where science meets society [In an age of discovery and innovation, how can benefits be passed along?

    International Nuclear Information System (INIS)

    Science and scientists play a vital role in society. The degree of influence wielded by scientific opinion, the reputation of scientific bodies for impartially rendered insight, the priority accorded to scientific research and education all have contributed to the success of nations. The frontiers of science have never looked more promising than they do today. Opportunities abound. From nanotechnology, to bioengineering, to terahertz imaging, to string theory, to space science, we are in an Age of Discovery and Innovation. The challenge is how to mine these opportunities for all they are worth to impact human health and welfare and security, and to have greater public understanding of, and respect and appreciation for, science. If we continue to invest in science and engineering research across a range of disciplines, develop human capital, engage on key public policy issues pro-actively and consistently, and engage the public in new, creative and respectful ways,we can heal rifts and address rising expectations worldwide.Terrorism and national security are top-of-the-mind issues in the US, and of concern worldwide. There are various technologies being used to identify and track potential terrorists. The public, especially in the US, has a general feeling of unease, while some worry about the effect of security measures on civil liberties, and others worry about the scientific community itself on the ease of communication and interaction with scientists worldwide for the advance of science. What is not clear is how comprehensively current vulnerabilities are assessed. This is where the scientific community can play a much needed role, and can contribute to a more open discussion, not of terrorist targets, or specifically how risk assessment is used, but at least that it is used. We cannot protect against everything. But, we can use risk assessment to deploy resources in an efficacious way, to track the right things, to aggravate people less, and to calm unnecessary

  5. Skin Care and Aging

    Science.gov (United States)

    ... Home » Skin Care and Aging Heath and Aging Skin Care and Aging Dry Skin and Itching Bruises Wrinkles Age Spots ... doctor. For More Information About Skin Care and Aging American Academy of Dermatology 1-866-503-7546 ( ...

  6. Signal transduction, receptors, mediators and genes: younger than ever - the 13th meeting of the Signal Transduction Society focused on aging and immunology

    Directory of Open Access Journals (Sweden)

    Klotz Lars-Oliver

    2010-02-01

    Full Text Available Abstract The 13th meeting of the Signal Transduction Society was held in Weimar, from October 28 to 30, 2009. Special focus of the 2009 conference was "Aging and Senescence", which was co-organized by the SFB 728 "Environmentally-Induced Aging Processes" of the University of Düsseldorf and the study group 'Signal Transduction' of the German Society for Cell Biology (DGZ. In addition, several other areas of signal transduction research were covered and supported by different consortia associated with the Signal Transduction Society including the long-term associated study groups of the German Society for Immunology and the Society for Biochemistry and Molecular Biology, and for instance the SFB/Transregio 52 "Transcriptional Programming of Individual T Cell Subsets" located in Würzburg, Mainz and Berlin. The different research areas that were introduced by outstanding keynote speakers attracted more than 250 scientists, showing the timeliness and relevance of the interdisciplinary concept and exchange of knowledge during the three days of the scientific program. This report gives an overview of the presentations of the conference.

  7. Social-Strata-Related Cardiovascular Health Disparity and Comorbidity in an Aging Society: Implications for Professional Care

    Science.gov (United States)

    Ai, Amy L.; Carrigan, Lynn T.

    2007-01-01

    Cardiovascular disease (CVD) is on the rise in the aging population of the United States. Heart disease is the leading cause of death, hospital bed use, and social security disability. Enhancing knowledge about CVD may improve social work's professional role in the health care system. This article focuses on a pressing CVD-related issue that needs…

  8. Population aging and legal retirement age

    OpenAIRE

    Lacomba, Juan Antonio; Lagos, Francisco Miguel

    2005-01-01

    This paper analyzes the effects of population aging on the preferred legal retirement age. What is revealed is the crucial role that the indirect ???macro??? effects resulting from a change in the legal retirement age play in the optimal decision. Two Social Security systems are studied. Under a defined contribution scheme aging lowers the preferred legal retirement age. However, under a defined pension scheme the retirement age is delayed. This result shows the relevance of correctly c...

  9. 老龄化社会的住宅建筑设计研究%Research on the residential building design of aging society

    Institute of Scientific and Technical Information of China (English)

    张红梅

    2015-01-01

    Aiming at the present situation of our country has entered the aging society,discusses the main trend of endowment pattern in China under the trend of aging society transformation.To the elderly and special needs in physiological,psychological and social three aspects as the basis,in a safe,convenient,comfortable and healthy for the principle,from the external environment should be built with residential facilities to start,to the internal details of the design concept of residential,To study the design ideas and countermeasures suitable for our aging society of residential buildings.%本文针对我国已经进入老龄化社会的现状,探讨了老龄化社会转型趋势下中国养老模式的主流趋势。并以老年人在生理、心理、社会三方面的特殊需求为依据,以安全、便利、舒适和健康为原则,从老龄住宅外部环境应配建的设施入手,到老龄住宅的内部细节设计理念,研究探讨适合我国老龄社会的住宅建筑的设计思路与对策。

  10. Packaging development in an ageing society: a case study approach in the United Kingdom fast-moving consumer goods industry

    OpenAIRE

    Ford, Nicholas

    2014-01-01

    There is a growing body of research demonstrating the effects of age-related changes on product usability and the value derived from consumption experiences. In particular, difficulties with packaging have been identified as a source of dissatisfaction and a key barrier to older people maintaining their independence. Despite this, marketing literature into older consumers’ packaging experiences is limited. Likewise, packaging development has been afforded scant attention in the new product...

  11. Aging and Aged in Organized Crime.

    Science.gov (United States)

    Amir, Menachem

    1989-01-01

    Examines problems of the aged in organized crime, basing discussion on organized crime bosses over age 60 operating in Italy, the United States, and Israel. Looks at problems stemming from normative system in organized crime, role of the aged, intergenerational problems, fears of the aged, excuses and justifications, standards of life, and…

  12. Oral Health and Aging

    Science.gov (United States)

    ... please turn JavaScript on. Feature: Oral Health and Aging Oral Health and Aging Summer 2016 Table of Contents Jerrold H. Epstein, ... they may need. Read More "Oral Health and Aging" Articles Oral Health and Aging / 4 Myths About ...

  13. Skin Care and Aging

    Science.gov (United States)

    ... page please turn Javascript on. Skin Care and Aging How Aging Affects Skin Your skin changes with age. It ... if they bother you. See additional resources on aging skin, including information on treatment options, specific conditions, ...

  14. The Biology of Aging.

    Science.gov (United States)

    Sprott, Richard L.; And Others

    1992-01-01

    Thirteen articles in this special issue discuss aging theories, biomarkers of aging, aging research, disease, cancer biology, Alzheimer's disease, stress, oxidation of proteins, gene therapy, service delivery, biogerontology, and ethics and aging research. (SK)

  15. Population Aging and Inventive Activity

    OpenAIRE

    Irmen, Andreas; Litina, Anastasia

    2016-01-01

    This research empirically establishes and theoretically motivates the hypothesis that population aging has a hump-shaped effect on inventive activity. We estimate this hump-shaped relationship in a panel of 33 OECD countries over the period 1960-2012. The increasing part of the hump captures the awareness that population aging requires inventive activity to guarantee current and future standards of living. The decreasing part reflects the tendency of aging societies to lose dynamism and the w...

  16. How much might a society spend on life-saving interventions at different ages while remaining cost-effective? A case study in a country with detailed data

    OpenAIRE

    Kvizhinadze, Giorgi; Wilson, Nick; Nair, Nisha; McLeod, Melissa; Blakely, Tony

    2015-01-01

    Objective We aimed to estimate the maximum intervention cost (EMIC) a society could invest in a life-saving intervention at different ages while remaining cost-effective according to a user-specified cost-effectiveness threshold. Methods New Zealand (NZ) was used as a case study, and a health system perspective was taken. Data from NZ life tables and morbidity data from a burden of disease study were used to estimate health-adjusted life-years (HALYs) gained by a life-saving intervention. Hea...

  17. Avoiding Aging? Social Psychology's Treatment of Age

    Science.gov (United States)

    Barrett, Anne E.; Redmond, Rebecca; von Rohr, Carmen

    2012-01-01

    Population aging, in conjunction with social and cultural transformations of the life course, has profound implications for social systems--from large-scale structures to micro-level processes. However, much of sociology remains fairly quiet on issues of age and aging, including the subfield of social psychology that could illuminate the impact of…

  18. Age and Value Orientations

    Directory of Open Access Journals (Sweden)

    Asya Kh. Kukubayeva

    2013-01-01

    Full Text Available The present article deals with value orientations and their role in men’s lives, particularly, in young people’s lives. This notion was introduced by the American theoretical sociologist T. Parsons, one of the creators of modern theoretical sociology. The scientist made an attempt to construct the structural and analytical theory of social action, combining personal interests (needs and aims and situation, it takes place in. The issue of value orientations remains acute for psychology. Herein we have considered several most important works, relating to the considered issue. Age aspects of young people’s value orientations are of peculiar interest to us. When analyzing this phenomenon, one should take into consideration the psychological formations, inhere for a certain age. In fact every age has its unique structure, which may change when passing from one development stage to another. Basing on this fact, we’ve considered the values, depending on the age features of the youth, relying upon the works of the scientists, working with different categories of the youth, such as: teenagers, students, children of different nationalities. It is not surprising that most scientists have come to the conclusion that the chief role in value orientation belongs to a family, originates in relations with parents and teachers. The positive reinforcement to the future develops throughout life in accordance with a lifestyle of a family, society and political situation in a state.Life orientations as a type of value orientations show different types of young people’s preferences. Value structure of its consciousness has its own specific character, depending on the age peculiarities. The dynamics of the transition from one age to another is accompanied with the reappraisal of values, eventually, influencing the life strategy of the future generation

  19. Nutrition and Ageing.

    Science.gov (United States)

    Minuti, Andrea; Patrone, Vania; Giuberti, Gianluca; Spigno, Giorgia; Pietri, Amedeo; Battilani, Paola; Ajmone Marsan, Paolo

    2014-01-01

    The world elderly population is rapidly increasing. This demographic change represents a new challenge for the society and demands for a multisectorial intervention to promote a long, healthy, and active life span. Between the factors that contribute in fostering a long healthy life, the nutritional regime plays a central role and is recognized as a major factor in the onset of chronic diseases. A better understanding of the interaction between nutrition and ageing is essential to unravel the mechanisms responsible for these positive/negative effects and to identify diet components promoting the quality of life in the old age and to contribute to the prevention of late-life disabilities. At Università Cattolica del Sacro Cuore, the research activity in food science is focusing on four main objectives: food quality, food safety, functional foods and diet balancing. These objectives are the target of multidisciplinary ongoing and future research activities for a better understanding of the link between diet and ageing. Briefly, the different activities are addressed to the study of the following subjects: the most relevant factors affecting food choices and habits of old aged persons; the effects of long term low dose supplementation of conjugated linoleic acid in mouse; the use of low glycemic index and high resistant starch foods to prevent diabetes and obesity; the adjuvant effect of food bacteria for vaccination; the role of food ingredients in disease; the immunosuppression effect of mycotoxins, and its relevance in ageing people; the production of sustainable and natural antioxidant ingredients to encourage a healthy diet. Our research projects emphasize an holistic and integrated approach that, by bringing together complementary research groups, can combine the collective expertise and thus provide a comprehensive assessment of the role of nutrition in healthy ageing people. PMID:26630518

  20. Dominant perceptions on the age

    Directory of Open Access Journals (Sweden)

    Komatina Slavica

    2003-01-01

    Full Text Available Contemporary developed society, despite the fact that it is constantly and intensively ageing, is characterized by deeply rooted numerous negative stereotypes on old people and old age as a life period. The study of dominant perceptions on the age of Belgrade population takes not only the universal character of negative connotation of old age into consideration, but also the concrete unfavorable social context. The delicate problematic of stereotypes on old age and old people has been analyzed mostly indirectly, through questions on the beginning of old age, advantages and difficulties which we experience during ageing, the first subjective conscious encounter with one’s own ageing, the concept of ideal old age, changes in the persons traits and directly through questions on dominant negative perceptions which prevail on old people in our surrounding. Ageing in the Belgrade milieu is most commonly identified with illness and with the decline of physical potentials, and at the same time a number of other negative qualifications of old age as well. Research results indicate to a pronounced ambivalent standpoint towards ageing, to different observation of one’s own to old age of other people, to different consideration of old age among the sexes and to obvious aversion towards old people. This is expected, taking into consideration that living and ageing are developing nowadays under aggressive influence of contemporary mass culture which affirms youth, beauty, physical strength, health as dominant values, namely everything that is contrary to ageing and old age. On the other hand, our society is today confronted with, as well as in the near past, exceptional political, economic and cultural difficulties which cause specific problems with various age groups, as well as the lowering of the level of mutual endurance and tolerance. The atmosphere of straining the old people and emergence of new antagonisms causes the intensification of

  1. Healthy Aging -- Sexual Health

    Science.gov (United States)

    ... address Submit Home > Healthy Aging > Sexual health Healthy Aging This information in Spanish ( en español ) Sexual health ... to discuss with your doctor. Sexual Health and Aging: Keep the Passion Alive (Copyright © Mayo Foundation) - This ...

  2. Administration on Aging

    Science.gov (United States)

    ... Federal Initiatives Career Opportunities Contact Us Administration on Aging (AoA) The Administration on Aging (AOA) is the ... themselves. Back to top Older Americans Act and Aging Network To meet the diverse needs of the ...

  3. Aging changes in sleep

    Science.gov (United States)

    ... this page: //medlineplus.gov/ency/article/004018.htm Aging changes in sleep To use the sharing features ... cycle is repeated several times during the night. AGING CHANGES With aging, sleep patterns tend to change. ...

  4. Higher Education in the Philippines and Malaysia:The Learning Region in the Age of Knowledge-Based Societies

    Directory of Open Access Journals (Sweden)

    Lorraine Symaco

    2012-04-01

    Full Text Available In the context of the developing world, the notion of the knowledge society has elicited a response especially among higher education institutions (HEIs and the role of this sector in developing human resources that are able to adapt and compete in such a society has led to the recognition of the government. In the case of the Philippines and Malaysia, for the country to be 'knowledge-'‐economy ready', its HEIs must embrace and facilitate a technology-'‐based orientation. This paper will look at the role of higher education in both the Philippines and Malaysia in relation to the requirements of the 'knowledge-'‐based' driven economy and how this sector responds and adapts to the challenging call to 'modernise' in order to perform and maximise its contribution to such objectives. Issues relating to this trend are also examined.

  5. Being private in the surveillance society : the concept of privacy in the age of terror, CCTV and electronic surveillance

    OpenAIRE

    Thesslin, Glen

    2011-01-01

    Abstract: Defending the right to privacy is a growing concern in modern society as surveillance, as a formidable weapon in the “war on terror”, becomes more intrusive with every passing year. In order to effectively defend the right to privacy one must know what privacy actually is. Privacy does not have one universal definition, but is a concept that has evolved though varied socio-cultural and historical circumstances, and is constantly being re-contextualised. This paper ...

  6. Spectral ageing a new age perspective

    CERN Document Server

    Rawlings, S; Rawlings, Katherine M Blundell & Steve

    2002-01-01

    We present an up-to-date critique of the physical basis for the spectral ageing method. We find that the number of cases where this method may be meaningfully applied to deduce the ages of classical double radio sources is small indeed. This critique is much more than merely a re-expression of anxieties about the calibration of spectral ageing (which have been articulated by others in the past).

  7. THE ROLE OF THE UNIVERSITY IN THE KNOWLEDGE SOCIETY: ETHICAL PERSPECTIVES ON ACADEMIC RESEARCH IN THE AGE OF CORPORATE SCIENCE

    Directory of Open Access Journals (Sweden)

    MARIA CERNAT

    2011-04-01

    Full Text Available Knowledge society lies on the ruins of national culture that thought people to function in a single universal form of science. This type of society is tightly related to a post-national multicultural world that nourishes the erosion of classical (Kantian and Humboldian cultural and scientific foundations of the university. We are now witnessing it’s transformation into a “multiversity” dominated by the competitive international academic market for students and scholars and “commodified” knowledge. The fiscal crisis of publicly financed universities forced them to constantly pursue other forms of income, the industry being the most obvious solution. In the place of universities of reason and culture the drastic decrease of public funding generated the commercialization of the universities. This is because there is an “asymmetric convergence”: while universities are adopting corporate values and principles the industry itself is not influenced by the academic values and norms. The pursuit of knowledge for mere intellectual curiosity and also the conception of the knowledge as a public good have been abandoned in favor of applied research serving corporate interests. The resulting academic capitalism is far from being the best solution to budget cuts and this study is trying to highlight some of advantages but also the most important shortcomings of this present trend in our universities.

  8. Experiences and Revelations of Dealing with Population Aging in International Society%国际社会应对老龄化的经验和启示

    Institute of Scientific and Technical Information of China (English)

    原新

    2015-01-01

    人口老龄化是全球共同的未来景象,发达国家老龄化进程超前于我国,应对老龄社会的许多创新做法和改革措施都值得我们学习和借鉴。在应对老龄社会方面,强调政府重视和经济社会政策顶层设计,鼓励生育和积极的移民方案,促进老年人力资源开发利用和老年社会参与;在应对老年人问题上,强调政府、市场、家庭和个人共同应对,不但要重视对老年特殊人群的保障,还要加强对全体老年人的保障,提倡医养结合,完善老年人健康和社会照护体系,在强化社会化养老基础上继续巩固家庭和居家养老,精细化分级服务,既关心特殊人群的养老,又关注健康人群的助老。%Population aging is a common future vision in the world. The Aging process in the developed country is ahead of that in China and their innovations and reform measures dealing with aging society deserve our learning. In the aspect of coping with aging society, it is emphasized that the government should attach importance to top-level design of economic and social policies, encourage childbirth and positive immigrant projects, and promote human resource development and social participation of the elderly. In the aspect of the solving elderly problem, it is emphasized that the government, market, families and the elderly themselves should face it together. We should not only pay attention to the safeguard for the special elderly, but also reinforce the security to all the old people. It is necessary to advocate “the combination of medical care and the pension”, complete health and social care system for the elderly, intensify social pension system and stabilize home-based care system, classify the services, achieve the aim that taking care for both the special group and the health group of the old at the same time.

  9. Aging of gaseous detectors

    International Nuclear Information System (INIS)

    This paper makes an overview of developments in the wire chamber aging field since the wire chamber aging workshop held at the Lawrence Berkeley Laboratory, Berkeley, California on January 16--17, 1986. The author discusses new techniques to analyze the gas impurities and the wire aging products, wire ''nonaging'' in clean systems, wire aging in systems containing various impurities, various examples of problems which can ''prime'' surfaces prior to the occurrence of the aging, and some recent aging experience with the ''SSC micro-straw tubes.'' 35 refs., 10 figs., 2 tabs

  10. National Institute on Aging

    Science.gov (United States)

    ... Join Our Mailing List Email The Leader in Aging Research NIA, one of the 27 Institutes and ... broad scientific effort to understand the nature of aging and to extend the healthy, active years of ...

  11. Aging changes in immunity

    Science.gov (United States)

    ... cells and antibodies that destroy these harmful substances. Aging Changes and Their Effects on the Immune System ... Prevention To decrease the risks from immune system aging: Get the flu and pneumonia vaccines, and any ...

  12. NIA Aging Cell Repository

    Data.gov (United States)

    Federal Laboratory Consortium — To facilitate aging research on cells in culture, the NIA provides support for the NIA Aging Cell Repository, located at the Coriell Institute for Medical Research...

  13. Corrected Age for Preemies

    Science.gov (United States)

    ... Prenatal Baby Bathing & Skin Care Breastfeeding Crying & Colic Diapers & Clothing Feeding & Nutrition Preemie Sleep Teething & Tooth Care Toddler Preschool Gradeschool Teen Young Adult Healthy Children > Ages & Stages > Baby > Preemie > Corrected Age ...

  14. Alaska Radiometric Ages

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — The Alaska Radiometric Age file is a database of radiometric ages of rocks or minerals sampled from Alaska. The data was collected from professional publications...

  15. Aging changes in immunity

    Science.gov (United States)

    ... this page: //medlineplus.gov/ency/article/004008.htm Aging changes in immunity To use the sharing features ... cells and antibodies that destroy these harmful substances. Aging Changes and Their Effects on the Immune System ...

  16. Memory and Aging

    Science.gov (United States)

    Memory and Aging Losing keys, misplacing a wallet, or forgetting someone’s name are common experiences. But for people nearing or over age 65, such memory lapses can be frightening. They wonder if they ...

  17. Components of aging

    OpenAIRE

    Wiegand, Iris

    2013-01-01

    Age-related cognitive decline has been linked to a reduction in attentional resources that are assumed to result from alterations in the aging brain. A core ability that is subject to age-related decline is visual attention, which enables individuals to select the most important information for conscious processing and action. However, visual attention is considered a conglomerate of various functions and the specific components underlying age differences in performance remain little understo...

  18. Optimal Aging and Death

    DEFF Research Database (Denmark)

    Dalgaard, Carl-Johan; Strulik, Holger

    representative consumer is subject to physiological aging. In modeling aging we draw on recent research in the fields of biology and medicine. The speed of the aging process, and thus the time of death, are endogenously determined by optimal health investments. We calibrate the model to US data and proceed to...

  19. Optimal Aging and Death

    DEFF Research Database (Denmark)

    Dalgaard, Carl-Johan Lars; Strulik, Holger

    2010-01-01

    This study introduces physiological aging into a simple model of optimal intertemporal consumption. In this endeavor we draw on the natural science literature on aging. According to the purposed theory, the speed of the aging process and the time of death are endogenously determined by optimal...

  20. Age and Farmer Productivity

    OpenAIRE

    Tauer, Loren W.

    1994-01-01

    Farmer productivity by age was estimated, allowing for differences because of efficiency and returns to scale. Using Census of Agriculture data, estimates vary by state, but returns to scale average 1.07. Efficiency increases average 4.5 percent every ten years of age, to the age interval 35 to 44, and then decreases at that same rate.

  1. Peroxisomes in yeast ageing

    NARCIS (Netherlands)

    Kumar, Sanjeev

    2015-01-01

    Ageing is characterized by the progressive decline in cellular functions that eventually leads to death. In human, ageing is associated with several age-related diseases such as cancer, cardiovascular disorders and neurodegenerative diseases. Over the years, research performed in several simpler sho

  2. PerformAge

    DEFF Research Database (Denmark)

    Fristrup, Tine

    2012-01-01

    ), I do not want to paint a uniformly rosy picture of aging and old age, but unfold an opening up of life taking the heroines and heroes of aging life to the open road in search of themselves and new roles in life as a quest of self-knowledge, self-development – a role for the future. Different...

  3. Hodgkin's disease and age

    DEFF Research Database (Denmark)

    Specht, L.; Nissen, N.I.

    1989-01-01

    modality, stage, and total tumour burden, whereas age had no prognostic significance. With regard to death from Hodgkin's disease only age and total tumour burden had independent significance. The significance of age would seem to stem from the fact that some older patients could not be given adequate...

  4. Osteoclasts prefer aged bone

    DEFF Research Database (Denmark)

    Henriksen, K; Leeming, Diana Julie; Byrjalsen, I;

    2007-01-01

    We investigated whether the age of the bones endogenously exerts control over the bone resorption ability of the osteoclasts, and found that osteoclasts preferentially develop and resorb bone on aged bone. These findings indicate that the bone matrix itself plays a role in targeted remodeling of...... aged bones....

  5. Intergenerational Justice in Aging Societies

    DEFF Research Database (Denmark)

    Vanhuysse, Pieter

    I present the Intergenerational Justice Index (IJI) - a simple four-dimensional indicator developed with the Bertelsmann Stiftung in order to compare intergenerational justice in practice across 29 OECD member states. The unit of analysis is countries, and the IJI is a macro-level snapshot linked...... ecological footprint created by all generations alive today; (2) early-life starting conditions as measured by child poverty levels; and (3) the economic and fiscal burdens on the shoulders of currently young generations as measured by public debt levels per child. The fourth IJI dimension measures policy...

  6. 老龄社会生育政策新内涵%New Connotation of Family Planning Policy in Aging Society

    Institute of Scientific and Technical Information of China (English)

    胡乃军; 于淼

    2013-01-01

    在老龄社会,生育政策必须与国家人力资源发展规划相匹配。本文运用人口数据建立老龄化的时间表,代入计划生育政策变量,建立预测和分析模型,观察其对人口总量和人口结构的影响,论证了二胎间隔生育政策的必要性。继而运用典型案例分析方法进一步证明二胎间隔生育政策的可行性,由此推论生育政策内涵从“节制生育”到“调节人口结构和控制总量”的新内涵转变及其实现路径。%In aging society, family planning policy must be matched to the national human resource development planning. To demonstrate the necessity of the two-child policy, this paper first uses population data to form an aging timetable and establish the forecasting and analytical model to observe the impact of family planning policy on total population and population structure. Then the paper further demonstrates the feasibility of two-child policy by a case study. Based on the above analysis, one can draw a conclusion that the connotation of family planning policy should be changed from“birth control”to“adjusting population structure and controlling the total population”. Finally, the ways of implementation are discussed.

  7. Ageing Management of CARR

    International Nuclear Information System (INIS)

    The paper introduced the ageing management of CARR, including the ageing management system, instances of ageing components, difficulties we met and follow up plan, and put forward some suggestions on strengthening and promoting ageing management. We hope to enhance international exchange and collaboration. It is a great challenge to do research on how to manage ageing effectively in the beginning of life, but it will enhance the safety of reactor operation, extend the life of the reactor and improve the quality of operation, making this work very meaningful

  8. Can aging be 'drugged'?

    Science.gov (United States)

    Riera, Celine E; Dillin, Andrew

    2015-12-01

    The engines that drive the complex process of aging are being identified by model-organism research, thereby providing potential targets and rationale for drug studies. Several studies of small molecules have already been completed in animal models with the hope of finding an elixir for aging, with a few compounds showing early promise. What lessons can we learn from drugs currently being tested, and which pitfalls can we avoid in our search for a therapeutic for aging? Finally, we must also ask whether an elixir for aging would be applicable to everyone, or whether we age differently, thus potentially shortening lifespan in some individuals. PMID:26646496

  9. Carcinogenesis and aging

    International Nuclear Information System (INIS)

    This 2-voluem set discusses the problem of inter-relation between carcinogenesis and aging, and the phenomenon of age-related increase in cancer incidence in animals and humans. Covered topics include current concepts in mechanisms of carcinogenesis and aging; data on chemical, radiation, ultraviolet-light, hormonal and viral carcinogenesis in aging; data on the role of age-related shifts in the activity of carcinogen-metabolizing enzymes; binding of carcinogens with macromolecules; DNA repair; tissue proliferation; and immunity and homono-metabolic patterns in realization of initiation and promotion of carcinogenesis

  10. Heart Age PSA (:60)

    Centers for Disease Control (CDC) Podcasts

    2015-09-01

    This 60 second public service announcement is based on the September 2015 CDC Vital Signs report. Your heart age is the age of your heart and blood vessels as a result of your risk factors for heart attack and stroke. If you smoke or have high blood pressure, your heart age will be much higher than your actual age. Learn what you can do to lower your heart age and keep it low.  Created: 9/1/2015 by National Center for Chronic Disease Prevention and Health Promotion (NCCDPHP).   Date Released: 9/1/2015.

  11. Wages, productivity and aging

    OpenAIRE

    Dostie, Benoît

    2006-01-01

    In this article, we estimate age based wage and productivity differentials using linked employer-employee Canadian data from the Workplace and Employee Survey 1999-2003. Data on the firm side is used to estimate production functions taking into account the age profile of the firm's work-force. Data on the workers' side is used to estimate wage equations that also depend on age. Results show concave age-wage and age-productivity profiles. Wage-productivity comparisons show that the productivit...

  12. UV, stress and aging.

    Science.gov (United States)

    Debacq-Chainiaux, Florence; Leduc, Cedric; Verbeke, Alix; Toussaint, Olivier

    2012-07-01

    Skin is a model of choice in studies on aging. Indeed, skin aging can be modulated by internal and external factors, reflecting its complexity. Two types of skin aging have been identified: intrinsic, mainly genetically determined and extrinsic-also called "photo-aging"-resulting on the impact of environmental stress and more precisely of UV rays. Simplified in vitro models, based on cellular senescence, have been developed to study the relationship between UV and aging. These models vary on the cell type (fibroblasts or keratinocytes, normal or immortalized) and the type of UV used (UVA or UVB). PMID:23467762

  13. On aging and aged care in Serbia.

    Science.gov (United States)

    Sevo, G; Davidovic, M; Erceg, P; Despotovic, N; Milosevic, D P; Tasic, M

    2015-06-01

    Serbia is a demographically old nation, with 17.4 % of its residents being aged 65 years and older in 2011. The previous two decades of turbulent history have significantly affected the demographic picture of this country, and their ramifications remain visible in Serbia's economic, political, cultural, and health spheres. Major demographic forces behind population aging in Serbia can be attributed to lower fertility rates, migrations, and declining mortality (reflecting improvements in overall health leading to a longer life expectancy). In Serbia, low fertility and migrations appear to play major roles, although the relative contribution of recent migrations cannot be measured with accuracy. Patterns of demographic aging vary considerably across different geographic, socioeconomic, and cultural settings. The common denominator throughout present day Serbia is extensive political and economic transition. One would expect that, given sufficient time, this process will result in improved population health, and yet, at this stage outcomes of major health care reform in Serbia are somewhat perplexing. For the second consecutive year, Serbia's health care system has been ranked at the very bottom of the scale among 34 European countries. It is then no surprise that the elderly represent particularly vulnerable population segment. This paper discusses some of the issues relevant to these demographic patterns of aging and aged care in contemporary Serbia, focusing on the period after 2000. PMID:25943380

  14. Aging male syndrome

    Directory of Open Access Journals (Sweden)

    Valer Donca

    2012-12-01

    Full Text Available Aging Male Syndrome is a medical condition through which men could pass between the ages of 35 and 65, when testosterone levelsin their body decline considerably. Androgen deficiency in the aging male has become a topic of increasing interest and debate throughout theworld. In contrast to female menopause, the process of aging in the male genital system is slow and highly variable between individuals. Thecharacteristic symptoms of Aging Male Syndrome include weakness, depression, fatigue and changes in body hair and skin, decreased sexualdesire, decreased lean body mass accompanied by increased visceral fat, decreased bone mineral density. Aging Male Syndrome is usually diagnosedby testing the blood for testosterone levels. The usual treatment method for Aging Male Syndrome includes testosterone injections,testosterone patches, testosterone gels and oral preparations.

  15. Skin mirrors human aging.

    Science.gov (United States)

    Nikolakis, Georgios; Makrantonaki, Evgenia; Zouboulis, Christos C

    2013-12-01

    Abstract Aged skin exhibits disturbed lipid barrier, angiogenesis, production of sweat, immune functions, and calcitriol synthesis as well as the tendency towards development of certain benign or malignant diseases. These complex biological processes comprise endogenous and exogenous factors. Ethnicity also markedly influences the phenotype of skin aging. The theories of cellular senescence, telomere shortening and decreased proliferative capacity, mitochondrial DNA single mutations, the inflammation theory, and the free radical theory try to explain the biological background of the global aging process, which is mirrored in the skin. The development of advanced glycation end-products and the declining hormonal levels are major factors influencing intrinsic aging. Chronic photodamage of the skin is the prime factor leading to extrinsic skin aging. The deterioration of important skin functions, due to intrinsic and extrinsic aging, leads to clinical manifestations, which mirror several internal age-associated diseases such as diabetes, arterial hypertension and malignancies. PMID:25436743

  16. Active ageing technologies

    DEFF Research Database (Denmark)

    Lassen, Aske Juul

    physical and productive activity; e.g. that a game of billiards is a technology of active aging. Thus, active aging is enacted in the socio-material practices of the technologies in this paper. The paper contributes with a strengthening of the concept of active aging, by focusing on entangled practices and...... elderly. As part of this rearticulation of old age, many new technologies take form. This paper uses a wide concept of technologies (devices, regimes, strategies and ways of doing) and argues that technologies form active aging subjectivities, and on the other hand, that these subjectivities in their...... socio-material practices form active aging. Hence, active aging is a mutual entanglement (Callon and Rabeharisoa 2004) between technologies, practices and subjectivities. The paper is based on four months of participant observations and 17 in-depth interviews with elderly persons conducted at three...

  17. Mitochondria and the aging heart

    Institute of Scientific and Technical Information of China (English)

    Ketul R Chaudhary; Haitham El-Sikhry; John M Seubert

    2011-01-01

    The average human life span has markedly increased in modern society largely attributed to advances in medical and therapeutic sciences that have successfully reduced important health risks.However,advanced age results in numerous alterations to cellular and subcellular components that can impact the overall health and function of an individual.Not surprisingly,advanced age is a major risk factor for the development of heart disease in which elderly populations observe increased morbidity and mortality.Even healthy individuals that appear to have normal heart fimction under resting conditions,actually have an increased susceptibility and vulnerability to stress.This is confounded by the impact that stress and disease can have over time to both the heart and vessels. Although, there is a rapidly growing body of literature investigating the effects of aging on the heart and how age-related alterations affect cardiac fimction, the biology of aging and underlying mechanisms remain unclear .In this review,we summarize effects of aging on the heart and discuss potential theories of cellular aging with special emphasis on mitochondrial dysfunction.

  18. EPL comes of age

    Science.gov (United States)

    Jérome, Denis

    2007-01-01

    Twenty-one years have now passed since the launch of Europhysics Letters which merged the physics letters journals of two learned societies: Journal de Physique Lettres and Lettere al Nuovo Cimento belonging, respectively, to the French Physical Society (SFP) and to the Italian Physical Society (SIF). This new journal was also supported by the UK Institute of Physics (IOP) and many other National Physical Societies, members of the European Physical Society (EPS). The aim of this merger was expressed by the words of G. H. Stafford, the President of EPS in 1985, for whom Europhysics Letters marked `an important milestone in the progress towards greater unity in Europe' which began with the creation of the European Physical Society nearly twenty years earlier. Europhysics Letters was supposed to be a strong European-based journal for the publication of short important communications covering all domains of physics under the supervision and the scientific control of EPS. In 2007, 21 years later, Europhysics Letters has now come of age and the Board of Directors, under the control of EPS, has decided to mature the journal, now re-branded as EPL and characterized by a new cover design and a new printed format, thus encouraging development into a top-tier journal, a leading global home for ground-breaking physics research letters. The objective is to make EPL a high-impact physics journal leading towards an increase in visibility, impact, prestige, scientific quality, reputation and impact factor although all scientists are currently aware that the presentation of impact factors must be taken with a grain of salt. A new publishing contract amongst the EPL partners will directly involve, besides EDPS (the publishing company of SFP) and SIF, the Institute of Physics through its publishing department (IOP Publishing) in a more active role, its task being hosting the on-line facilities of the journal. The combined publishing expertise and marketing knowledge of EDPS, IOP

  19. Healthy Aging in China

    OpenAIRE

    Smith, James P.; Strauss, John; Zhao, Yaohui

    2014-01-01

    China has aged rapidly and the rate is accelerating in decades to come. We review positive and negative forces for healthy aging in China now and in the future. The most positive force is the spectacular growth in education over time especially for Chinese women, which should improve all dimensions of cognitive and physical health and eliminate vast gender disparities in healthy aging that currently exist.

  20. The aging lung

    Directory of Open Access Journals (Sweden)

    Lowery EM

    2013-11-01

    Full Text Available Erin M Lowery,1 Aleah L Brubaker,2 Erica Kuhlmann,1 Elizabeth J Kovacs31Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine at Loyola University Medical Center, 2Loyola University Stritch School of Medicine, 3Department of Surgery, Loyola University Medical Center, Maywood, IL, USAAbstract: There are many age-associated changes in the respiratory and pulmonary immune system. These changes include decreases in the volume of the thoracic cavity, reduced lung volumes, and alterations in the muscles that aid respiration. Muscle function on a cellular level in the aging population is less efficient. The elderly population has less pulmonary reserve, and cough strength is decreased in the elderly population due to anatomic changes and muscle atrophy. Clearance of particles from the lung through the mucociliary elevator is decreased and associated with ciliary dysfunction. Many complex changes in immunity with aging contribute to increased susceptibility to infections including a less robust immune response from both the innate and adaptive immune systems. Considering all of these age-related changes to the lungs, pulmonary disease has significant consequences for the aging population. Chronic lower respiratory tract disease is the third leading cause of death in people aged 65 years and older. With a large and growing aging population, it is critical to understand how the body changes with age and how this impacts the entire respiratory system. Understanding the aging process in the lung is necessary in order to provide optimal care to our aging population. This review focuses on the nonpathologic aging process in the lung, including structural changes, changes in muscle function, and pulmonary immunologic function, with special consideration of obstructive lung disease in the elderly.Keywords: aging, lung, pulmonary immunology, COPD

  1. We Are Ageing

    OpenAIRE

    Kolovou, Genovefa D; Kolovou, Vana; Mavrogeni, Sophie

    2014-01-01

    Ageing and longevity is unquestioningly complex. Several thoughts and mechanisms of ageing such as pathways involved in oxidative stress, lipid and glucose metabolism, inflammation, DNA damage and repair, growth hormone axis and insulin-like growth factor (GH/IGF), and environmental exposure have been proposed. Also, some theories of ageing were introduced. To date, the most promising leads for longevity are caloric restriction, particularly target of rapamycin (TOR), sirtuins, hexarelin and ...

  2. Optimal Aging and Death

    DEFF Research Database (Denmark)

    Dalgaard, Carl-Johan Lars; Strulik, Holger

    2010-01-01

    This study introduces physiological aging into a simple model of optimal intertemporal consumption. In this endeavor we draw on the natural science literature on aging. According to the purposed theory, the speed of the aging process and the time of death are endogenously determined by optimal...... health investments. At the same time, physiological aspects of the aging process influence optimal savings and health investment. We calibrate the model for the average US male in 2000 and proceed to show that the calibrated model accounts well for the cross-country link between labor productivity and...

  3. Age, wage and productivity

    OpenAIRE

    van Ours, J.C.; Stoeldraijer, L.

    2010-01-01

    Previous empirical studies on the effect of age on productivity and wages find contradicting results. Some studies find that if workers grow older there is an increasing gap between productivity and wages, i.e. wages increase with age while productivity does not or does not increase at the same pace. However, other studies find no evidence of such an age related pay-productivity gap. We perform an analysis of the relationship between age, wage and productivity using a matched worker-firm pane...

  4. Hodgkin's disease and age

    DEFF Research Database (Denmark)

    Specht, L; Nissen, N I

    1989-01-01

    506 unselected, previously untreated patients with Hodgkin's disease were treated at the Finsen Institute between 1969 and 1983. The prognostic significance of age, sex, stage, systemic symptoms, histologic subtype, number of involved nodal regions, total tumour burden (peripheral + intrathoracic...... modality, stage, and total tumour burden, whereas age had no prognostic significance. With regard to death from Hodgkin's disease only age and total tumour burden had independent significance. The significance of age would seem to stem from the fact that some older patients could not be given adequate...

  5. The Development of Cognitive, Language, and Cultural Skills from Age 3 to 6: A Comparison between Children of Turkish Origin and Children of Native-Born German Parents and the Role of Immigrant Parents' Acculturation to the Receiving Society

    Science.gov (United States)

    Becker, Birgit; Klein, Oliver; Biedinger, Nicole

    2013-01-01

    This article analyzes the longitudinal development of differences in academic skills between children of Turkish origin and children of native-born German parents from age 3 to 6 in Germany with a focus on the role of immigrant parents' acculturation to the receiving society. Growth curve models show that Turkish-origin children start with lower…

  6. The aging population: demographics and the biology of aging.

    Science.gov (United States)

    Kanasi, Eleni; Ayilavarapu, Srinivas; Jones, Judith

    2016-10-01

    profile and the effects of an aging society on the prevalence and incidence of periodontal diseases. We review the definitions of normal and successful aging, the principles of geriatric medicine and the highlights of biological aging at cellular, tissue and systems levels. PMID:27501488

  7. Telomeres and reproductive aging.

    Science.gov (United States)

    Keefe, David L; Liu, Lin

    2009-01-01

    Infertility, miscarriage and aneuploid offspring increase with age in women, and meiotic dysfunction underlies reproductive aging. How aging disrupts meiotic function in women remains unclear, but as women increasingly delay having children, solving this problem becomes an urgent priority. Telomeres consist of a (TTAGGG)(n) repeated sequence and associated proteins at chromosome ends, mediate aging in mitotic cells and may also mediate aging during meiosis. Telomeres shorten both during DNA replication and from the response to oxidative DNA damage. Oocytes do not divide in adult mammals, but their precursors do replicate during fetal oogenesis; eggs ovulated from older females have traversed more mitotic cell cycles before entering meiosis during fetal oogenesis than eggs ovulated from younger females. Telomeres also would be expected to shorten from inefficient DNA repair of oxidative damage, because the interval between fetal oogenesis and ovulation is exceptionally prolonged in women. We have tested the hypothesis that telomere shortening disrupts meiosis by shortening telomeres experimentally in mice, which normally do not exhibit age-related meiotic dysfunction. Interestingly, mouse telomeres are much longer than human telomeres, but genetic or pharmacological shortening of mouse telomeres recapitulates in mice the human reproductive aging phenotype as the mouse telomeres reach the length of telomeres from older women. These observations led us to propose a telomere theory of reproductive aging. Moreover, chronological oxidative stress increases with reproductive aging, leading to DNA damage preferentially at (TTAGGG)(n) repeats. Finally, if telomeres shorten with aging, how do they reset across generations? Telomerase could not play a significant role in telomere elongation during early development, because this enzyme is not active until the blastocyst stage, well after the stage when telomere elongation takes place. Rather, telomeres lengthen during the

  8. Nutrients, Microglia Aging, and Brain Aging

    OpenAIRE

    Zhou Wu; Janchun Yu; Aiqin Zhu; Hiroshi Nakanishi

    2016-01-01

    As the life expectancy continues to increase, the cognitive decline associated with Alzheimer’s disease (AD) becomes a big major issue in the world. After cellular activation upon systemic inflammation, microglia, the resident immune cells in the brain, start to release proinflammatory mediators to trigger neuroinflammation. We have found that chronic systemic inflammatory challenges induce differential age-dependent microglial responses, which are in line with the impairment of learning and ...

  9. 老龄化城市老年代步工具设计研究%RESEARCH ON WALK-ASSISTANT TOOL DESIGN FOR AGING SOCIETY

    Institute of Scientific and Technical Information of China (English)

    李丹; 陈虹

    2015-01-01

    The aging trend is a hot issue that we have to face and the "silver economy" era provides a new direction and more needs for us. However, in Chinese society, the research and design for seniors are relatively lack. It is particularly serious for seniors to go out. Focusing on the real needs of older users, the paper is to expound the specific advice and supply the design suggestion through a analysis of living behavior, physiological characteristics and the emotional appeal by questionnaire investigation and interview of the seniors. The purpose is to promote the development of senor products.%社会老龄化是我国正在面临的一个重要课题,随之而来的“银发经济”时代为我们提供了一个新的指导方向,引发了更多市场需求。然而目前中国社会在这方面有很大的空白,老年人出行难的问题尤为突出。本文关注老年用户的真正需求,以设计研究适合老年人出行的代步工具为目的,对老年人的生活行为、生理特点、情感诉求进行分析,同时以问卷调查和访谈的形式研究老年人使用代步工具的生活形态和行为特点,并提出具体的设计建议。

  10. Biology of ageing

    DEFF Research Database (Denmark)

    Rattan, Suresh

    2015-01-01

    Living systems owe their survival and health to a series of complex biochemical pathways of maintenance and repair. These defense systems create the homeodynamic space of an individual, which is characterized by stress tolerance, molecular damage control and continuous remodeling. Ageing, age-rel...

  11. Healthy ageing through music

    OpenAIRE

    Perkins, Rosie; Bisschop Boele, E.H.; Smilde, Rineke

    2012-01-01

    Presentation in session ‘Healthy Ageing through Music’. Presentations: - Rineke Smilde: Music and Dementia - Evert Bisschop Boele: Creative Workshops with the Elderly - Rosie Burt-Perkins: Healthy ageing through instrumental music learning World Conference ISME, Thessaloniki, Greece, 20/7/2012

  12. The ageing spine

    International Nuclear Information System (INIS)

    This book contain 15 selections. Some of the titles are: Effects of age on the appearance of magnetic resonance images of the spine; Potential for image analysis in quantitative magnetic resonance imaging of the aging spine; Potential of x-ray diffraction computed tomography for discriminating between normal and osteoporotic bone; and Spinal fusion in the elderly

  13. The age of Schumpeter

    OpenAIRE

    Giersch, Herbert

    1983-01-01

    The centenary of Schumpeter's birth coincides with a revival of Schumpeterian economics. Could the third quarter of this Century justly be called the age of Keynes (Hicks, 1974), the fourth quarter has a fair chance of becoming the age of Schumpeter. Before giving substance to this proposition, I shall present a Short introduction to Schumpeter's life, work and paradigm.

  14. Age, Wage and Productivity

    NARCIS (Netherlands)

    van Ours, J.C.; Stoeldraijer, L.

    2010-01-01

    Previous empirical studies on the effect of age on productivity and wages find contradicting results. Some studies find that if workers grow older there is an increasing gap between productivity and wages, i.e. wages increase with age while productivity does not or does not increase at the same pace

  15. Aging, longevity and health

    DEFF Research Database (Denmark)

    Rasmussen, Lene Juel; Sander, Miriam; Wewer, Ulla M.;

    2011-01-01

    Session included speeches by Ralf Hemmingsen, Ulla Wewer, and Lene Juel Rasmussen and Keynote Addresses by four world renowned aging researchers: Povl Riis (The Age Forum), Bernard Jeune (University of Southern Denmark), George Martin (University of Washington, USA) and Jan Vijg (Albert Einstein School of...

  16. COOEE bitumen: chemical aging

    CERN Document Server

    Lemarchand, Claire A; Dyre, Jeppe C; Hansen, Jesper S

    2013-01-01

    We study chemical aging in "COOEE bitumen" using molecular dynamic simulations. The model bitumen is composed of four realistic molecule types: saturated hydrocarbon, resinous oil, resin, and asphaltene. The aging reaction is modelled by the chemical reaction: "2 resins $\\rightarrow$ 1 asphaltene". Molecular dynamic simulations of four bitumen compositions, obtained by a repeated application of the aging reaction, are performed. The stress autocorrelation function, the fluid structure, the rotational dynamics of the plane aromatic molecules, and the diffusivity of each molecule, are determined for the four different compositions. The aging reaction causes a significant dynamics slowdown, which is correlated to the aggregation of asphaltene molecules in larger and dynamically slower nanoaggregates. Finally, a detailed description of the role of each molecule types in the aggregation and aging processes is given.

  17. Parylene C Aging Studies.

    Energy Technology Data Exchange (ETDEWEB)

    Achyuthan, Komandoor; Sawyer, Patricia Sue.; Mata, Guillermo Adrian; White II, Gregory Von; Bernstein, Robert

    2014-09-01

    Parylene C is used in a device because of its conformable deposition and other advantages. Techniques to study Parylene C aging were developed, and %22lessons learned%22 that could be utilized for future studies are the result of this initial study. Differential Scanning Calorimetry yielded temperature ranges for Parylene C aging as well as post-deposition treatment. Post-deposition techniques are suggested to improve Parylene C performance. Sample preparation was critical to aging regimen. Short-term (~40 days) aging experiments with free standing and ceramic-supported Parylene C films highlighted %22lessons learned%22 which stressed further investigations in order to refine sample preparation (film thickness, single sided uniform coating, machine versus laser cutting, annealing time, temperature) and testing issues (%22necking%22) for robust accelerated aging of Parylene C.

  18. Snubber aging assessment

    International Nuclear Information System (INIS)

    Snubbers are safety-related devices used to restrain undesirable dynamic loads at various piping and equipment locations in nuclear power plants (NPPs). Each snubber must accommodate a plant's normal thermal movements and be capable of restraining the maximum off-normal dynamic loads postulated for its specific location. The effects of snubber aging and the environments and mechanisms that degrade snubber performance need to be better understood. This paper describes the Phase II Nuclear Plant Aging Research Program in-plant aging research conducted to enhance the understanding of snubber aging and its consequences. Pacific Northwest Laboratory staff and their subcontractors, Lake Engineering and Wyle Laboratories, visited eight sites (encompassing thirteen plants) to conduct interviews with NPP staff and to collet snubber aging, testing, and maintenance data. The research methodology, evaluations, results, conclusions, and recommendations are described in the paper. Effective methods for service-life monitoring of snubbers are included in the recommendations. (orig.)

  19. Gene and Aging

    Directory of Open Access Journals (Sweden)

    DD Farhud

    2008-09-01

    Full Text Available "nCollection of multiple processes that increase the chronological age of an organism leading to death is defined as aging, and even though important, it is poorly understood. Recent research has shown that aging is due to biochemical and genetic changes, in interaction with environmental effects, including diet and nutrition. Most knowledge on aging is based on ge­netic model system, but its molecular mechanisms are still not very clear. Discoveries in molecular biology have made way to look for candidate genes influencing lifespan. Furthermore, new investigations have stressed on the roles of mitochondria as the major generators and direct targets of reactive oxygen species. This paper reviews some recent literature on genes and ag­ing in model system, then discusses the role of mitochondria and nutrients in human aging.

  20. Overview of facial aging.

    Science.gov (United States)

    Beer, Kenneth; Beer, Jacob

    2009-12-01

    Facial aging is a multidimensional, multifactorial process. The aging face has traditionally been treated by each specialty in a different manner. However, by understanding the process from the perspective of different specialties, each physician may better treat the spectrum of facial aging. Whether or not the facial plastic surgeon injects products to restore volume, uses lasers to resurface the epidermis and dermis, incorporates cosmeceuticals to enhance and maintain improvements in the skin integrity and appearance, or relaxes muscles with botulinum toxins, he or she can best advise patients and address facial aging by having a functional understanding of these various modalities. With this knowledge, the facial plastic surgeon can parse the component of facial aging that enables him or her to correct each with the appropriate treatment. PMID:20024868

  1. An Age-Old Problem

    Institute of Scientific and Technical Information of China (English)

    2011-01-01

    Rapidly aging society will challenge China’s future labor force HUANG Sanbi,65,once an accountant in a university in Beijing,has been retired for nearly 10 years.Her day is full and well scheduled.Doing morning exercises, studying ways of maintaining her health and having fun with the family have become her daily "obligatory courses." She is one of the lucky ones,leading a happy life in her old age,not worrying about things like pension and medical insurance. However,many senior citizens in rural areas or with medium and low income are not well prepared for their retirement.Problems caused by an aging population pose a big challenge to China’s future development,despite its recent economic progress.

  2. Epigenetics and aging

    Science.gov (United States)

    Pal, Sangita; Tyler, Jessica K.

    2016-01-01

    Over the past decade, a growing number of studies have revealed that progressive changes to epigenetic information accompany aging in both dividing and nondividing cells. Functional studies in model organisms and humans indicate that epigenetic changes have a huge influence on the aging process. These epigenetic changes occur at various levels, including reduced bulk levels of the core histones, altered patterns of histone posttranslational modifications and DNA methylation, replacement of canonical histones with histone variants, and altered noncoding RNA expression, during both organismal aging and replicative senescence. The end result of epigenetic changes during aging is altered local accessibility to the genetic material, leading to aberrant gene expression, reactivation of transposable elements, and genomic instability. Strikingly, certain types of epigenetic information can function in a transgenerational manner to influence the life span of the offspring. Several important conclusions emerge from these studies: rather than being genetically predetermined, our life span is largely epigenetically determined; diet and other environmental influences can influence our life span by changing the epigenetic information; and inhibitors of epigenetic enzymes can influence life span of model organisms. These new findings provide better understanding of the mechanisms involved in aging. Given the reversible nature of epigenetic information, these studies highlight exciting avenues for therapeutic intervention in aging and age-associated diseases, including cancer. PMID:27482540

  3. [Normal aging and cognition].

    Science.gov (United States)

    Ska, Bernadette; Joanette, Yves

    2006-03-01

    It is now well documented that normal aging modifies the cognitive functioning and most observations suggest that cognition evolves in the direction of deterioration. The more frequently impaired functions are memory, attention and visual-spatial abilities. On the other hand, some abilities seem to increase, such as vocabulary. Considering the aging effect on cognition, questions remain regarding directionality, universality and reversibility. A great variability in aged related impacts is observed among subjects and among cognitive domains. Some individuals evolved more rapidly than others. Some cognitive functions are more affected by aging than others. General and specific factors are hypothesized to explain the aged related cognitive decline. Among them, educational level, health, cognitive style, life style, personality, are likely to modulate the aged related cognitive evolution by influencing attentional resources and cerebral plasticity. Cognitive resources are essential to develop adaptative strategies. During the life span, resources are activated and increased by learning and training. Considering the role of cognitive resources, successful aging is dependent on several conditions : absence of disease leading to a loss of autonomy, maintenance of cognitive and physical activities, and active and social engaged lifestyle. PMID:16527210

  4. Three ages of Venus

    Science.gov (United States)

    Wood, Charles A.; Coombs, Cassandra R.

    1989-01-01

    A central question for any planet is the age of its surface. Based on comparative planetological arguments, Venus should be as young and active as the Earth (Wood and Francis). The detection of probable impact craters in the Venera radar images provides a tool for estimating the age of the surface of Venus. Assuming somewhat different crater production rates, Bazilevskiy et al. derived an age of 1 + or - 0.5 billion years, and Schaber et al. and Wood and Francis estimated an age of 200 to 400 million years. The known impact craters are not randomly distributed, however, thus some area must be older and others younger than this average age. Ages were derived for major geologic units on Venus using the Soviet catalog of impact craters (Bazilevskiy et al.), and the most accessible geologic unit map (Bazilevskiy). The crater counts are presented for (diameters greater than 20 km), areas, and crater densities for the 7 terrain units and coronae. The procedure for examining the distribution of craters is superior to the purely statistical approaches of Bazilevskiy et al. and Plaut and Arvidson because the bins are larger (average size 16 x 10(6) sq km) and geologically significant. Crater densities define three distinct groups: relatively heavily cratered (Lakshmi, mountain belts), moderately cratered (smooth and rolling plains, ridge belts, and tesserae), and essentially uncratered (coronae and domed uplands). Following Schaber et al., Grieve's terrestrial cratering rate of 5.4 + or - 2.7 craters greater than 20 km/10(9) yrs/10(6) sq km was used to calculate ages for the geologic units on Venus. To improve statistics, the data was aggregated into the three crater density groups, deriving the ages. For convenience, the three similar age groups are given informal time stratigraphic unit names, from youngest to oldest: Ulfrunian, Sednaian, Lakshmian.

  5. Forever young or ageing naturally?

    NARCIS (Netherlands)

    Van Hees, R.P.J.; Naldini, S.

    2014-01-01

    Age and ageing can be felt as negative occurrences. For monuments however, old age is traditionally considered to be a positive quality. Without a certain age the nomination of monument hardly applies. Ageing can be seen as the work of time, which has always been valued: ageing was sometimes even ar

  6. Growth hormone and aging

    OpenAIRE

    Bartke, Andrzej; Brown-Borg, Holly; Kinney, Beth; Mattison, Julie; Wright, Chris; Hauck, Steven; Coschigano, Karen; Kopchick, John

    2000-01-01

    The potential usefulness of growth hormone (GH) as an anti-aging therapy is of considerable current interest. Secretion of GH normally declines during aging and administration of GH can reverse age-related changes in body composition. However, mutant dwarf mice with congenital GH deficiency and GH resistant GH-R-KO mice live much longer than their normal siblings, while a pathological elevation of GH levels reduces life expectancy in both mice and men. We propose that the actions of GH on gro...

  7. Vitamin D and Aging

    OpenAIRE

    Gallagher, J. Christopher

    2013-01-01

    Aging affects the formation of 1,25-dihydroxyvitamin D (1,25[OH]2D; calcitriol), the active form of vitamin D. Production of 1,25(OH)2D is reduced by 50% as a result of an age-related decline in renal function, although serum 1,25(OH)2D levels are maintained in part by secondary hyperparathyroidism. Aging also causes a decrease in calcium absorption that precedes the decrease in 1,25(OH)2D by 10 to 15 years. Because 1,25(OH)2D is dependent on an adequate supply of the substrate vitamin D, the...

  8. [Epidermal aging and anti-aging strategies].

    Science.gov (United States)

    Wohlrab, J; Hilpert, K; Wolff, L

    2016-02-01

    Epithelial senescence is a complex process depending on intrinsic as well as extrinsic factors (e.g., UV or IR light, tobacco smoke) and must be seen in the context of the aging process especially of the corium and the subcutis. Morphological alterations become apparent in the form of epithelial atrophy, structural changes within the basal membrane, and a decrease in cell count of melanocytes and Langerhans cells. Signs of cellular senescence are reduced proliferation of keratinocytes, cumulation of dysplastic keratinocytes, various mutations (e.g., c-Fos/c-Jun, STAT3, FoxO1), as well as multiple lipid or amino acid metabolic aberrations (e.g., production of advanced glycation endproducts). This causes functional changes within the physical (lipid deficiency, water distribution dysfunction, lack of hygroscopic substances), chemical (pH conditions, oxygen radicals), and immunological barrier. Prophylactically, barrier-protective care products, antioxidant substances (e.g., vitamin C, B3, E, polyphenols, flavonoids), sunscreen products/measurements, and retinoids are used. For correcting alterations in aged epidermis, chemical peelings (fruit acids, β-hydroxy acid, trichloroacetic acid, phenolic compounds), non-ablative (IPL, PDL, Nd:YAG) as well as ablative (CO2, Erbium-YAG) light-assisted methods are used. PMID:26636143

  9. The Role of Functional Foods in Cutaneous Anti-aging

    OpenAIRE

    Cho, Soyun

    2014-01-01

    Oral supplementation of micronutrients, or functional foods, to prevent aging has gained much attention and popularity as society ages and becomes more affluent, and as science reveals the pathological mechanisms of aging. Aging of the skin combines biologic aging and extrinsic aging caused predominantly by sunlight and other environmental toxins. Anti-aging functional foods exert their influence mostly through their anti-oxidant and anti-inflammatory effects, thereby abrogating collagen degr...

  10. Aging Random Walks

    CERN Document Server

    Böttcher, S

    1997-01-01

    Aging refers to the property of two-time correlation functions to decay very slowly on (at least) two time scales. This phenomenon has gained recent attention due to experimental observations of the history dependent relaxation behavior in amorphous materials (``Glasses'') which pose a challenge to theorist. Aging signals the breaking of time-translational invariance and the violation of the fluctuation dissipation theorem during the relaxation process. But while the origin of aging in disordered media is profound, and the discussion is clad in the language of a well-developed theory, systems as simple as a random walk near a wall can exhibit aging. Such a simple walk serves well to illustrate the phenomenon and some of the physics behind it.

  11. HEU age determination

    International Nuclear Information System (INIS)

    A technique has been developed to determine the Highly Enriched Uranium (HEU) Age which is defined as the time since the HEU was produced in an enrichment process. The HEU age is determined from the ratios of relevant uranium parents and their daughters viz 230Th/234U and 231Pa/235U. Uranium isotopes are quantitatively measured by their characteristic gammas and their daughters by alpha spectroscopy. In some of the samples where HEU is enriched more than 99%, the only mode of HEU age determination is by the measurement of 231Pa since there is negligible quantity of 230Th due to very low atom concentrations of 234U in the sample. In this paper we have presented data and methodology of finding the age of two HEU samples

  12. Global Health and Aging

    Science.gov (United States)

    ... 9 12 16 18 20 22 25 4 Global Health and Aging Preface The world is facing ... stages of economic development and with varying resources. Global efforts are required to understand and find cures ...

  13. Sleep and Aging

    Science.gov (United States)

    ... version of this page please turn Javascript on. Sleep and Aging About Sleep We all look forward to a good night's ... health and quality of life. Two Types of Sleep There are two types of sleep: non-rapid ...

  14. Sleep and Aging: Insomnia

    Science.gov (United States)

    ... page please turn Javascript on. Sleep and Aging Insomnia Insomnia is the most common sleep complaint at ... at greater risk for falling. Health Issues and Insomnia Disorders that cause pain or discomfort during the ...

  15. Ageing and skills

    DEFF Research Database (Denmark)

    Desjardins, Richard; Warnke, Arne Jonas

    The relationship between ageing and skills is becoming an important policy issue, not least in the context of population ageing. Data from the Programme for the International Assessment of Adult Competencies (PIAAC) will potentially add considerably to the understanding of the relationship between...... ageing and foundation skills. In particular, the fact that data from the 1994-1998 International Adult Literacy Survey (IALS) and the 2003-2007 Adult Literacy and Lifeskills Survey (ALL) will be linked with PIAAC offers a unique opportunity to examine trends over time at the cohort level for a wide range...... of countries. Specifically, repeated measures will enable an analysis of whether there is skill gain and skill loss over the lifespan of cohorts and overtime between cohorts. This is especially important because age-skill profiles observed on the basis of a single cross-section are difficult to...

  16. Ageing of research reactors

    International Nuclear Information System (INIS)

    Historically, many of the research institutions were centred on a research reactor facility as main technological asset and major source of neutrons for research. Important achievements were made in time in these research institutions for development of nuclear materials technology and nuclear safety for nuclear energy. At present, ageing of nuclear research facilities among these research reactors and ageing of staff are considerable factors of reduction of competence in research centres. The safe way of mitigation of this trend deals with ageing management by so called, for power reactors, Plant Life Management and new investments in staff as investments in research, or in future resources of competence. A programmatic approach of ageing of research reactors in correlation with their actual and future utilisation, will be used as a basis for safety evaluation and future spending. (author)

  17. Forest Stand Age

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — Source data for forest stand age were obtained from the USDA Forest Inventory and Analysis (FIA) DataMart and were projected for future scenarios based on selected...

  18. Cellular Homeostasis and Aging.

    Science.gov (United States)

    Hartl, F Ulrich

    2016-06-01

    Aging and longevity are controlled by a multiplicity of molecular and cellular signaling events that interface with environmental factors to maintain cellular homeostasis. Modulation of these pathways to extend life span, including insulin-like signaling and the response to dietary restriction, identified the cellular machineries and networks of protein homeostasis (proteostasis) and stress resistance pathways as critical players in the aging process. A decline of proteostasis capacity during aging leads to dysfunction of specific cell types and tissues, rendering the organism susceptible to a range of chronic diseases. This volume of the Annual Review of Biochemistry contains a set of two reviews addressing our current understanding of the molecular mechanisms underlying aging in model organisms and humans. PMID:27050288

  19. The Role of the General Practitioners in Aging Society%论人口老龄化社会中全科医生的作用

    Institute of Scientific and Technical Information of China (English)

    司庆燕; 陈士福; 潘洪伟

    2014-01-01

    中国已经进入老龄化社会,城市社区和农村基层仍有一些老年人缺乏医疗卫生保障,高龄慢性病老人成为看病最难的人群,需要培养更多的全科医生解决这一难题。宏观上,老龄化社会的全科医生可以产生一定的经济效益和广泛的社会效益;微观上,全科医生具有促使家庭医疗资源的有效利用、方便老年人就医、开展健康教育等作用。完善“全科医生-老年人”服务模式,需要政府进一步完善老年人医疗服务体系和保障体系,大力提升基层社区卫生服务机构的医疗条件,根据老年人的需要培养专门的全科医学人才,推行全科医生与老年人建立契约服务关系。%China has entered the aging society , in urban communities and rural grassroots their are still many older people lack of health insurance , elderly patients with chronic diseases become the most difficult people to see a doctor, this needs to train more general practitioners to solve these problems .From a macroscopical view , general practitioners can bring substantial economic benefits and broad social benefits .From a microscopic view , they also can make effective use of family medical resources , bring convenient for old people going to a doctor and carry out an important role of health education .Improving the "General Practitioner -Elderly"service mode , the govern-ment needs to further improve the elderly medical service system and security system , vigorously promote grass -roots community health service institutions of medical conditions , develop specialized general medical personnel ac-cording to the needs of the elderly , implement contractual service relationships between general practitioners and the elderly.

  20. Stress, Inflammation and Aging

    OpenAIRE

    Lavretsky, Helen; Newhouse, Paul A.

    2012-01-01

    This editorial provides a summary of the state of research on stress-related changes associated with aging and discuss how factors such as inflammation and sex steroid alterations may interact with psychosocial stress to affect the risk for mood and cognitive disturbance in older individuals. The authors provide an integrated summary of four studies reported in this issue of the journal and views on future direction in stress and aging research and interventions targeting resilience to stress.

  1. Evolution and Ageing

    OpenAIRE

    de Oliveira, S. Moss; Alves, Domingos; Martins, J. S. Sa

    2000-01-01

    The idea of this review is to connect the different models of evolution to those of biological ageing through Darwin's theory. We start with the Eigen model of quasispecies for microevolution, then introduce the Bak-Sneppen model for macroevolution and, finally, present the Penna model for biological ageing and some of its most important results. We also explore the concept of coevolution using this model.

  2. ELECTION ON RETIREMENT AGE

    OpenAIRE

    Francisco M. Lagos; Juan Antonio Lacomba

    2001-01-01

    We analyze the relationship between wage distribution, degree of redistribution of the Social Security and effective retirement age. We develop a two-staged political economy model. In the first stage government chooses the redistribution level of the Social Security Program, according to three different criteria. In second stage the retirement age is elected through a majority voting process by agents with different wages, knowing exactly the redistribution level and voting accordingly. We a...

  3. Modulating aging and longevity

    DEFF Research Database (Denmark)

    Rattan, Suresh

    Provides information and an evaluation of a variety of approaches tried for modulating aging and longevity, including dietary supplementation with antioxidants, vitamins and hormones, genetic engineering, life-style alterations, and hormesis through mild stress. After decades of systematic...... mild stress. The goal of research on ageing is not to increase human longevity regardless of the consequences, but to increase active longevity free from disability and functional dependence...

  4. Aging and sexuality.

    OpenAIRE

    Holzapfel, S.

    1994-01-01

    Recent research suggesting that a high proportion of men and women remain sexually active well into later life refutes the prevailing myth that aging and sexual dysfunction are inexorably linked. Age-related physiological changes do not render a meaningful sexual relationship impossible or even necessarily difficult. In men, greater physical stimulation is required to attain and maintain erections, and orgasms are less intense. In women, menopause terminates fertility and produces changes ste...

  5. Age Discrimination in Italy

    OpenAIRE

    Olga Rymkevitch; Claudia Villosio

    2007-01-01

    The Framework Directive on Equal Treatment in Employment and Occupation (2000/78/EC) included age as one of its prohibited grounds of discrimination. Member States were required to transpose this Directive by December 2003. In Italy age discrimination was explicitly regulated by means of Legislative Decree no. 216, 9 July 2003. The Decree introduced the new specific prohibition of discrimination, defining its application, exceptions and remedies. The purpose of this paper is to explore, in a ...

  6. Classifier in Age classification

    OpenAIRE

    B. Santhi; R.Seethalakshmi

    2012-01-01

    Face is the important feature of the human beings. We can derive various properties of a human by analyzing the face. The objective of the study is to design a classifier for age using facial images. Age classification is essential in many applications like crime detection, employment and face detection. The proposed algorithm contains four phases: preprocessing, feature extraction, feature selection and classification. The classification employs two class labels namely child and Old. This st...

  7. Exercise, Inflammation and Aging

    OpenAIRE

    Jeffrey A Woods; Wilund, Kenneth R.; Martin, Stephen A.; Kistler, Brandon M.

    2011-01-01

    Aging results in chronic low grade inflammation that is associated with increased risk for disease, poor physical functioning and mortality. Strategies that reduce age-related inflammation may improve the quality of life in older adults. Regular exercise is recommended for older people for a variety of reasons including increasing muscle mass and reducing risk for chronic diseases of the heart and metabolic systems. Only recently has exercise been examined in the context of inflammation. This...

  8. Midlife and Beyond: Issues for Aging Women.

    Science.gov (United States)

    Saucier, Maggi G.

    2004-01-01

    The author discusses issues confronted by aging women, particularly those related to ageism and body image, emphasizing society's role in influencing women's perceptions of their bodies. Although body image issues cause anxiety throughout most women's lives, women entering middle age become more conscious of this concern. Problems related to a…

  9. EPL comes of age

    Science.gov (United States)

    Jérome, Denis

    2007-01-01

    Twenty-one years have now passed since the launch of Europhysics Letters which merged the physics letters journals of two learned societies: Journal de Physique Lettres and Lettere al Nuovo Cimento belonging, respectively, to the French Physical Society (SFP) and to the Italian Physical Society (SIF). This new journal was also supported by the UK Institute of Physics (IOP) and many other National Physical Societies, members of the European Physical Society (EPS). The aim of this merger was expressed by the words of G. H. Stafford, the President of EPS in 1985, for whom Europhysics Letters marked `an important milestone in the progress towards greater unity in Europe' which began with the creation of the European Physical Society nearly twenty years earlier. Europhysics Letters was supposed to be a strong European-based journal for the publication of short important communications covering all domains of physics under the supervision and the scientific control of EPS. In 2007, 21 years later, Europhysics Letters has now come of age and the Board of Directors, under the control of EPS, has decided to mature the journal, now re-branded as EPL and characterized by a new cover design and a new printed format, thus encouraging development into a top-tier journal, a leading global home for ground-breaking physics research letters. The objective is to make EPL a high-impact physics journal leading towards an increase in visibility, impact, prestige, scientific quality, reputation and impact factor although all scientists are currently aware that the presentation of impact factors must be taken with a grain of salt. A new publishing contract amongst the EPL partners will directly involve, besides EDPS (the publishing company of SFP) and SIF, the Institute of Physics through its publishing department (IOP Publishing) in a more active role, its task being hosting the on-line facilities of the journal. The combined publishing expertise and marketing knowledge of EDPS, IOP

  10. Does an Aging Population Increase Inequality?

    OpenAIRE

    Weizsäcker, Robert K. von

    1995-01-01

    The paper reviews recent research on the impact of an aging population on the distribution of income. After briefly discussing the demographic conditions responsible for population aging, a short account is given of demographic trends in the industrialized world. In order to disentangle the many potential channels by which an aging society affects the dispersion of income, several levels of aggregation are distinguished. The paper differentiates between intra- and intergenerational issues, be...

  11. Brain atrophy during aging

    International Nuclear Information System (INIS)

    Age-related brain atrophy was investigated in thousands of persons with no neurologic disturbances using X-CT and NMR-CT. Brain atrophy was minimal in 34-35 years old in both sexes, increased exponentially to the increasing age after 34-35 years, and probably resulted in dementia, such as vascular or multi-infarct dementia. Brain atrophy was significantly greater in men than in women at all ages. Brain volumes were maximal in 34-35 years old in both sexes with minimal individual differences which increased proportionally to the increasing age. Remarkable individual differences in the extent of brain atrophy (20 - 30 %) existed among aged subjects. Progression of brain atrophy was closely related to loss of mental activities independently of their ages. Our longitudinal study has revealed that the most important factors promoting brain atrophy during aging was the decrease in the cerebral blood flow. We have classified brain atrophy into sulcal and cisternal enlargement type (type I), ventricular enlargement type (type II) and mixed type (type III) according to the clinical study using NMR-CT. Brain atrophy of type I progresses significantly in almost all of the geriatric disorders. This type of brain atrophy progresses significantly in heavy smokers and drinkers. Therefore this type of brain atrophy might be caused by the decline in the blood flow in anterior and middle cerebral arteries. Brain atrophy of type II was caused by the disturbance of cerebrospinal fluid circulation after cerebral bleeding and subarachnoid bleeding. Brain atrophy of type III was seen in vascular dementia or multi-infarct dementia which was caused by loss of brain matter after multiple infarction, and was seen also in dementia of Alzheimer type in which degeneration of nerve cells results in brain atrophy. NMR-CT can easily detect small infarction (lacunae) and edematous lesions resulting from ischemia and hypertensive encephalopathy. (J.P.N.)

  12. Cognitive aging in zebrafish.

    Directory of Open Access Journals (Sweden)

    Lili Yu

    Full Text Available BACKGROUND: Age-related impairments in cognitive functions represent a growing clinical and social issue. Genetic and behavioral characterization of animal models can provide critical information on the intrinsic and environmental factors that determine the deterioration or preservation of cognitive abilities throughout life. METHODOLOGY/PRINCIPAL FINDINGS: Behavior of wild-type, mutant and gamma-irradiated zebrafish (Danio rerio was documented using image-analysis technique. Conditioned responses to spatial, visual and temporal cues were investigated in young, middle-aged and old animals. The results demonstrate that zebrafish aging is associated with changes in cognitive responses to emotionally positive and negative experiences, reduced generalization of adaptive associations, increased stereotypic and reduced exploratory behavior and altered temporal entrainment. Genetic upregulation of cholinergic transmission attenuates cognitive decline in middle-aged achesb55/+ mutants, compared to wild-type siblings. In contrast, the genotoxic stress of gamma-irradiation accelerates the onset of cognitive impairment in young zebrafish. CONCLUSIONS/SIGNIFICANCE: These findings would allow the use of powerful molecular biological resources accumulated in the zebrafish field to address the mechanisms of cognitive senescence, and promote the search for therapeutic strategies which may attenuate age-related cognitive decline.

  13. [Strategies for successful ageing].

    Science.gov (United States)

    Orozco Ríos, Adriana Martha; López Velarde Peña, Tatiana; Martínez Gallardo Prieto, Lorenza

    2016-01-01

    There has been an increase in the interest of anti-ageing medicine in the last few years, with a growth in the industry of products that promise to prolong life and restore all the suffering or "defects" produced by age. The understanding of ageing has changed over the years, giving rise to the possibility of intervening in different metabolic and cellular pathways, and thus, delaying the appearance of the degenerative chronic diseases that appear with age, and that are finally the causing factors of the vulnerability that leads to our death. It is hoped that we can help the clinician to orientate their patients, who, due to the overwhelming amount of information they receive by the Internet, arrive at the clinic full of questions, waiting to receive absolute answer from their physician in order to increase their longevity and quality of life. This article presents an analysis of the physical activity, diets, supplements and drugs that are being investigated as anti-ageing measures and of the many clinical studies that have produced encouraging, measurable and reproducible results. PMID:26656211

  14. Aging and dark adaptation.

    Science.gov (United States)

    Jackson, G R; Owsley, C; McGwin, G

    1999-11-01

    Older adults have serious difficulty seeing under low illumination and at night, even in the absence of ocular disease. Optical changes in the aged eye, such as pupillary miosis and increased lens density, cannot account for the severity of this problem, and little is known about its neural basis. Dark adaptation functions were measured on 94 adults ranging in age from the 20s to the 80s to assess the rate of rod-mediated sensitivity recovery after exposure to a 98% bleach. Fundus photography and a grading scale were used to characterize macular health in subjects over age 49 in order to control for macular disease. Thresholds for each subject were corrected for lens density based on individual estimates, and pupil diameter was controlled. Results indicated that during human aging there is a dramatic slowing in rod-mediated dark adaptation that can be attributed to delayed rhodopsin regeneration. During the second component of the rod-mediated phase of dark adaptation, the rate of sensitivity recovery decreased 0.02 log unit/min per decade, and the time constant of rhodopsin regeneration increased 8.4 s/decade. The amount of time to reach within 0.3 log units of baseline scotopic sensitivity increased 2.76 min/decade. These aging-related changes in rod-mediated dark adaptation may contribute to night vision problems commonly experienced by the elderly. PMID:10748929

  15. Stress, Aging and Thirst

    Science.gov (United States)

    Greenleaf, John E.

    1998-01-01

    After growth during adolesence, total body water decreases progressively with aging from 65% of body weight to about 53% of body weight in the 70th decade; a majority of the loss occurs from the extracellular volume, from 42% to about 25%, respectively. Cellular volume also reaches equilibrium in the 70th decade at about 25% of body weight. Various stresses such as exercise, heat and attitude exposure, ad prior dehydration attenuate voluntary fluid intake (involuntary dehydration). Voluntary fluid intake appears to decrease with aging (involuntary dehydration in this sense aging can be considered as a stress. Kidney function and muscle mass (80% water) decrease somewhat with aging, and voluntary fluid intake (thirst) is also attenuated. Thirst is stimulated by increasing osmolality (hypernatremia) of the extracellular fluid and by decreased extracellular volume (mainly plasma volume) which act to increase intracellular fluid volume osmolality to activiate drinking. The latter decreases fluid compartment osmolality which ' It terminates drinking. However, this drinking mechanism seems to be attenuated with aging such that increasing plasma osmolality no longer stimulates fluid intake appropriately. Hypernatremia in the elderly has been associated all too frequently with greater incidence of bacterial infection and increased mortality. Involuntary dehydration can be overcome in young men by acclimation to an intermittent exercise-in-heat training program. Perhaps exercise training in the elderly would also increase voluntary fluid intake and increase muscle mass to enhance retention of water.

  16. Biological psychological and social determinants of old age: Bio-psycho-social aspects of human aging

    Directory of Open Access Journals (Sweden)

    Małgorzata Dziechciaż

    2014-11-01

    Full Text Available Biological psychological and social determinants of old age: Bio-psycho-social aspects of human aging. The aging of humans is a physiological and dynamic process ongoing with time. In accordance with most gerontologists’ assertions it starts in the fourth decade of life and leads to death. The process of human aging is complex and individualized, occurs in the biological, psychological and social sphere. Biological aging is characterized by progressive age-changes in metabolism and physicochemical properties of cells, leading to impaired self-regulation, regeneration, and to structural changes and functional tissues and organs. It is a natural and irreversible process which can run as successful aging, typical or pathological. Biological changes that occur with age in the human body affect mood, attitude to the environment, physical condition and social activity, and designate the place of seniors in the family and society. Psychical ageing refers to human awareness and his adaptability to the ageing process. Among adaptation attitudes we can differentiate: constructive, dependence, hostile towards others and towards self attitudes. With progressed age, difficulties with adjustment to the new situation are increasing, adverse changes in the cognitive and intellectual sphere take place, perception process involutes, perceived sensations and information received is lowered, and thinking processes change. Social ageing is limited to the role of an old person is culturally conditioned and may change as customs change. Social ageing refers to how a human being perceives the ageing process and how society sees it.

  17. The relationship between dental age, bone age and chronological age in underweight children

    OpenAIRE

    Vinod Kumar; Karthik Venkataraghavan; Ramesh Krishnan; Kavitha Patil; Karishma Munoli; Sandhya Karthik

    2013-01-01

    Background and Objective: The knowledge of bone age and dental age is of great importance for pediatrician and pediatric dentist. It is essential for a pediatric dentist to formulate treatment plan and it is a source of complementary information for pediatrician. There are few studies, which showed the relationship between dental age, bone age and chronological age in underweight children. Therefore, objective of this study was to determine and compare dental age, bone age and chronological a...

  18. 浅析健身气功在老龄化社会中的积极性作用%A Brief Analysis on the Positive Role of Fitness Qigong in the Aging Society

    Institute of Scientific and Technical Information of China (English)

    周筱霞

    2013-01-01

    China has entered the aging society. Fitness qigong possesses the characteristics of stretching and gentle movement, which plays a positive role in promoting senior citizens' health. Starting from the current situation, social pressure and improve-ment of China's aging population, this paper mainly deals with the positive role of fitness qigong in the aging society, and ex-pounds the unique role of fitness qigong in healthy aging from such three aspects as physical healthy, psychological health, and social adaptability.%目前我国已进入老龄化社会。健身气功动作舒展大方、缓慢柔和的特点对老年人健康促进起着积极的作用。本文从我国人口老龄化的现状与社会压力及健康老龄化入手,主要探讨健身气功在老龄化社会中发挥的积极性作用,分别从生理健康、心理健康和社会适应性三方面论述了健身气功对健康老龄化的独特作用。

  19. Signatures of aging

    Energy Technology Data Exchange (ETDEWEB)

    Cornwall, J.; Dyson, F.; Garwin, R.; Hammer, D.; Happer, W.; Lewis, N.; Schwitters, R.; Sullivan, J.; Williams, E.

    1998-01-06

    The Department of Energy and its three weapons laboratories (LANL, LLNL, and SNL) have developed a Stockpile Stewardship and Management Program (SSMP) in response to their designated mission of maintaining an effective, i.e. reliable and safe, nuclear deterrent without underground nuclear tests (UGTs). The need to ensure the effectiveness of an aging stockpile presents new challenges of major importance. In this study we review what is known about the aging of critical constituents, particularly the high explosives, polymers, and metals in the enduring stockpile. We discuss data that are required to provide a fuller understanding of aging, and how to obtain that data as a basis for anticipating and addressing potential stockpile problems. Our particular concern is problems that may arise in the short term, i.e. within the next 5 to 10 years, and their implied requirements for preventive maintenance and remanufacture.

  20. Cancer and aging

    DEFF Research Database (Denmark)

    Pedersen, Jacob K; Engholm, Gerda; Skytthe, Axel;

    2016-01-01

    Epidemiological cancer data shed light on key questions within basic science, clinical medicine and public health. For decades, Denmark has had linkable health registers that contain individual level data on the entire population with virtually complete follow-up. This has enabled high quality...... studies of cancer epidemiology and minimized the challenges often faced in many countries, such as uncertain identification of the study base, age misreporting, and low validity of the cancer diagnoses. However, methodological challenges still remain to be addressed, especially in cancer epidemiology...... studies among the elderly and the oldest-old. For example, a characteristic pattern for many cancer types is that the incidence increases up to a maximum at about ages 75-90 years and is then followed by a decline or a leveling off at the oldest ages. It has been suggested that the oldest individuals may...

  1. Ageing Management Program Database

    International Nuclear Information System (INIS)

    The aspects of plant ageing management (AM) gained increasing attention over the last ten years. Numerous technical studies have been performed to study the impact of ageing mechanisms on the safe and reliable operation of nuclear power plants. National research activities have been initiated or are in progress to provide the technical basis for decision making processes. The long-term operation of nuclear power plants is influenced by economic considerations, the socio-economic environment including public acceptance, developments in research and the regulatory framework, the availability of technical infrastructure to maintain and service the systems, structures and components as well as qualified personnel. Besides national activities there are a number of international activities in particular under the umbrella of the IAEA, the OECD and the EU. The paper discusses the process, procedure and database developed for Slovenian Nuclear Safety Administration (SNSA) surveillance of ageing process of Nuclear power Plant Krsko.(author)

  2. Glucose and Aging

    Science.gov (United States)

    Ely, John T. A.

    2008-04-01

    When a human's enzymes attach glucose to proteins they do so at specific sites on a specific molecule for a specific purpose that also can include ascorbic acid (AA) at a high level such as 1 gram per hour during exposure. In an AA synthesizing animal the manifold increase of AA produced in response to illness is automatic. In contrast, the human non-enzymatic process adds glucose haphazardly to any number of sites along available peptide chains. As Cerami clarified decades ago, extensive crosslinking of proteins contributes to loss of elasticity in aging tissues. Ascorbic acid reduces the random non-enyzmatic glycation of proteins. Moreover, AA is a cofactor for hydroxylase enzymes that are necessary for the production and replacement of collagen and other structural proteins. We will discuss the relevance of ``aging is scurvy'' to the biochemistry of human aging.

  3. Redox theory of aging

    Directory of Open Access Journals (Sweden)

    Dean P. Jones

    2015-08-01

    Full Text Available Metazoan genomes encode exposure memory systems to enhance survival and reproductive potential by providing mechanisms for an individual to adjust during lifespan to environmental resources and challenges. These systems are inherently redox networks, arising during evolution of complex systems with O2 as a major determinant of bioenergetics, metabolic and structural organization, defense, and reproduction. The network structure decreases flexibility from conception onward due to differentiation and cumulative responses to environment (exposome. The redox theory of aging is that aging is a decline in plasticity of genome–exposome interaction that occurs as a consequence of execution of differentiation and exposure memory systems. This includes compromised mitochondrial and bioenergetic flexibility, impaired food utilization and metabolic homeostasis, decreased barrier and defense capabilities and loss of reproductive fidelity and fecundity. This theory accounts for hallmarks of aging, including failure to maintain oxidative or xenobiotic defenses, mitochondrial integrity, proteostasis, barrier structures, DNA repair, telomeres, immune function, metabolic regulation and regenerative capacity.

  4. Genome instability and aging.

    Science.gov (United States)

    Vijg, Jan; Suh, Yousin

    2013-01-01

    Genome instability has long been implicated as the main causal factor in aging. Somatic cells are continuously exposed to various sources of DNA damage, from reactive oxygen species to UV radiation to environmental mutagens. To cope with the tens of thousands of chemical lesions introduced into the genome of a typical cell each day, a complex network of genome maintenance systems acts to remove damage and restore the correct base pair sequence. Occasionally, however, repair is erroneous, and such errors, as well as the occasional failure to correctly replicate the genome during cell division, are the basis for mutations and epimutations. There is now ample evidence that mutations accumulate in various organs and tissues of higher animals, including humans, mice, and flies. What is not known, however, is whether the frequency of these random changes is sufficient to cause the phenotypic effects generally associated with aging. The exception is cancer, an age-related disease caused by the accumulation of mutations and epimutations. Here, we first review current concepts regarding the relationship between DNA damage, repair, and mutation, as well as the data regarding genome alterations as a function of age. We then describe a model for how randomly induced DNA sequence and epigenomic variants in the somatic genomes of animals can result in functional decline and disease in old age. Finally, we discuss the genetics of genome instability in relation to longevity to address the importance of alterations in the somatic genome as a causal factor in aging and to underscore the opportunities provided by genetic approaches to develop interventions that attenuate genome instability, reduce disease risk, and increase life span. PMID:23398157

  5. The aging male project

    OpenAIRE

    Farid Saad

    2001-01-01

    With an increasing life expectancy and a decreasing reproduction rate, the population structure changes. A Jenapharm R & D program investigates the endocrinology of aging men. In men, a decrease in production of sex steroids and other hormones with age can be observed. The typical patterns of daily rhythmicity become less distinct. This is part of a very complex picture in which not only isolated hormones are involved, but also the influence of hormones on each other. Many factors from th...

  6. Religion and aging.

    Science.gov (United States)

    Margaret Hall, C

    1985-03-01

    Life history data and cultural values are used to suggest ways in which personal and social beliefs influence the quality of experiences of aging. Central questions are the extent to which an individual can select beliefs that lead to a longer, more meaningful life and the special influence that religion may have in enhancing aging. Responsiveness to needs of the elderly is a necessary component of enlightened planning for the future. Secularization and industrialization have diminished roles and expectations for the elderly. Religion may be an effective means to identify these concerns and improve the quality of life of older people. PMID:24307195

  7. Iron Age in Southeast Asia

    Directory of Open Access Journals (Sweden)

    Kishor K. Basa

    1991-11-01

    Full Text Available In this paper, I shall discuss the issue of the Iron Age in Southeast Asia under two headings - mainland Southeast Asia and island Southeast Asia. On the mainland, I shall discuss the evidence from Vietnani, Thailand and Peninsular Malaysia, but exclude Burma, Laos and Kampuchea for lack of relevant data. In the islands, I will discuss Indonesia, Sabah, Sarawak and the Philippines. I would argue that the Iron Age as a separate cultural entity is evident on the mainland, but in the islands there is no identifiable Bronze Age preceding the adoption of iron. By the Iron Age, I mean a period associated with iron artefacts, wet rice farming, brisk internal exchange and external trade and, in the lowland at least, a ranked society. This corresponds roughly to the General Period C of Bayard (1984b, 163, see also Higham and Kijngam 1984, 13-21. But two points should be made about this scheme: This is a heuristic device, so all sites in Southeast Asia can not be easily fitted into it.There is as yet no general agreement among scholars regarding the chronology of various periods.

  8. Raising the age of marriage.

    Science.gov (United States)

    1978-01-01

    The Indian Parliament approved the Child Marriage Restraint Bill, 1978, fixing the minimum age at marriage at 21 for boys, 18 for girls. Early marriage has a long tradition in India. Encouragement of late marriage will be difficult until parents are educated about the ill effects of early marriage. In traditional society the daughter has been considered a liability on the parents until she marries. Prepuberty marriage was intended to secure the purity of young girls. Demographic consequences of child marriages have been studied in Iran and indicate that if the age of marriage were 21 instead of 19, births would be reduced to 15%. In India, demographers have predicted that if marriages were postponed from the age of 16 to 20-21, the number of births would decrease to 25-30%. Low age at marriage also contributes to low standards of health for women and high mortality in child-bearing. Nearly 90% of early marriages are in rural areas where education is most needed. PMID:12261900

  9. Aging changes in the face

    Science.gov (United States)

    ... this page: //medlineplus.gov/ency/article/004004.htm Aging changes in the face To use the sharing ... Changes in face with age References Brodie SE. Aging and disorders of the eye. In: Fillit HM, ...

  10. IGBT accelerated aging data set.

    Data.gov (United States)

    National Aeronautics and Space Administration — Preliminary data from thermal overstress accelerated aging using the aging and characterization system. The data set contains aging data from 6 devices, one device...

  11. The challenges of human population ageing

    DEFF Research Database (Denmark)

    Sander, Miriam; Oxlund, Bjarke; Jespersen, Astrid;

    2015-01-01

    The 20th century saw an unprecedented increase in average human lifespan as well as a rapid decline in human fertility in many countries of the world. The accompanying worldwide change in demographics of human populations is linked to unanticipated and unprecedented economic, cultural, medical...... Copenhagen (UCPH) and the Center for Healthy Ageing at UCPH, which took place on 20-21 June 2014 in Copenhagen, Denmark. Questions discussed here include the following: what is driving age-structural change in human populations? how can we create 'age-friendly' societies and promote 'ageing...

  12. Aging of Organic Nanowires

    DEFF Research Database (Denmark)

    Balzer, Frank; Schiek, Manuela; Osadnik, Andreas;

    2012-01-01

    attribute, making them especially interesting for light generation in OLEDs and for light-harvesting devices such as solar cells. Functionalization of the molecules allows the customization of optical and electrical properties. However, aging of the wires might lead to a considerable decrease in device...

  13. Bronze Age Acrobats

    DEFF Research Database (Denmark)

    Iversen, Rune

    2014-01-01

    immaterial, ritual and cosmological exchange that characterized the second and early firstmillennium BC.Beliefs and ritual practices went hand in hand with the adoption of a series of elite items and an aristocratic lifestyle, thereby creating a unique and fascinating European Bronze Age....

  14. Time perception and age.

    Science.gov (United States)

    Ferreira, Vanessa Fernanda Moreira; Paiva, Gabriel Pina; Prando, Natália; Graça, Carla Renata; Kouyoumdjian, João Aris

    2016-04-01

    Our internal clock system is predominantly dopaminergic, but memory is predominantly cholinergic. Here, we examined the common sensibility encapsulated in the statement: "time goes faster as we get older". Objective To measure a 2 min time interval, counted mentally in subjects of different age groups. Method 233 healthy subjects (129 women) were divided into three age groups: G1, 15-29 years; G2, 30-49 years; and G3, 50-89 years. Subjects were asked to close their eyes and mentally count the passing of 120 s. Results The elapsed times were: G1, mean = 114.9 ± 35 s; G2, mean = 96.0 ± 34.3 s; G3, mean = 86.6 ± 34.9 s. The ANOVA-Bonferroni multiple comparison test showed that G3 and G1 results were significantly different (P < 0.001). Conclusion Mental calculations of 120 s were shortened by an average of 24.6% (28.3 s) in individuals over age 50 years compared to individuals under age 30 years. PMID:27097002

  15. Curcumin and aging

    Science.gov (United States)

    Curcumin has been used commonly as a spice, food additive, and an herbal medicine worldwide. Known as a bioactive polyphenolic, curcumin has a broad range of beneficial properties to human health. Recently, active research on curcumin with respect to aging and related traits in model organisms has d...

  16. Estrogens and aging skin

    OpenAIRE

    Thornton, M. Julie

    2013-01-01

    Estrogen deficiency following menopause results in atrophic skin changes and acceleration of skin aging. Estrogens significantly modulate skin physiology, targeting keratinocytes, fibroblasts, melanocytes, hair follicles and sebaceous glands, and improve angiogenesis, wound healing and immune responses. Estrogen insufficiency decreases defense against oxidative stress; skin becomes thinner with less collagen, decreased elasticity, increased wrinkling, increased dryness and reduced vascularity...

  17. Ageing and safety

    International Nuclear Information System (INIS)

    Ageing is a continuous process which cannot be reversed but which can be controlled by replacing components. However, the replacement of some components may be impossible or uneconomical; therefore, monitoring and in-service inspections must be increased. The combination of replacement of components and increased monitoring should make possible the total control of ageing. In this connection, it can be said that it is necessary to produce components and systems which are appropriate to the useful life of the facility, otherwise safety will be affected; that the materials used should be carefully selected so as to reduce activation problems; that in any new design, the need for components, systems and programmes for decontamination of the facility must be taken into account; that in order to control ageing, the increase in the level of monitoring and the replacement of components should be planned as a function of time; and that maintaining a constant level of design monitoring and increasing the rate of component replacement alone does not constitute control of ageing. It is not possible to replace all the components and those which cannot be replaced (reactor vessel, steam generators, pressurizer, heat exchangers, etc.) would present a high risk of failure if the monitoring of them were not stepped up so as to allow timely corrective action to be taken. (author)

  18. Taste perception with age

    NARCIS (Netherlands)

    Mojet, J.

    2004-01-01

    Keywords: age, thresholds, supra-threshold intensities, pleasantness, optimally preferred concentration, olfactory deprivation,signal-to-noise ratio

    This thesis

  19. PSYCHOLOGICAL ANTI-AGING

    OpenAIRE

    Mishchykha, Larysa

    2014-01-01

    The article focuses on the problem of a personality’s creative longevity. It is concluded that creative activity in the period of late ontogenesis should facilitate improvement of (a personality’s) life quality in the final period and, consequently, should become one of the significant factors of productive old age.

  20. CETA and the Aging.

    Science.gov (United States)

    Schram, Sanford F.; Osten, David F.

    1978-01-01

    To assess the impact of the 1973 Comprehensive Employment and Training Act (CETA) on older worker's problems, article examines CETA's history, options, and authority. Finds major systemic factors that encourage local prime sponsors to understate aging populations' needs. Concludes there is a need for substantial CETA changes to effectively serve…

  1. Psychological Aspects of Aging.

    Science.gov (United States)

    Mooney, Craig M.

    1980-01-01

    Psychological aspects of aging, based on gerontological hypotheses and research, are presented under three headings: intellectual abilities; emotional capacities; and motor capabilities. Consequences are discussed. Well-being throughout life depends on fulfillment of fundamental human needs; existential needs for nourishment, stimulation, rest,…

  2. A Bittersweet Age

    Institute of Scientific and Technical Information of China (English)

    2008-01-01

    They are the first generation bom under the one-child policy that came into eifect about 30 years ago. Today this post-80s generation are mostly aged between 20-28 and lead independent lives. Their unique family environment is a far cry from that of their parents’ generation, and has helped shape a personality of

  3. Helping You Age Well

    Science.gov (United States)

    ... Need and When / A Note on Complementary Medicines / Nutrition and the Aging Eye / In The Genes? Searching for Methuselah Winter 2007 Issue: Volume 2 Number 1 Page 9 MedlinePlus | Subscribe | Magazine Information | Contact Us | Viewers & Players Friends of the ...

  4. Chromium and aging

    Science.gov (United States)

    Aging is associated with increased blood glucose, insulin, blood lipids, and fat mass, and decreased lean body mass leading to increased incidences of diabetes and cardiovascular diseases. Improved chromium nutrition is associated with improvements in all of these variables. Insulin sensitivity de...

  5. Protein oxidation and ageing

    DEFF Research Database (Denmark)

    Linton, S; Davies, Michael Jonathan; Dean, R T

    2001-01-01

    of redox-active metal ions that could catalyse oxidant formation. As a result of this decrease in antioxidant defences, and increased rate of ROS formation, it is possible that the impact of ROS increases with age. ROS are known to oxidise biological macromolecules, with proteins an important target...

  6. Aging and the intestine

    Institute of Scientific and Technical Information of China (English)

    Laurie Drozdowski; Alan BR Thomson

    2006-01-01

    Over the lifetime of the animal, there are many changes in the function of the body's organ systems. In the gastrointestinal tract there is a general modest decline in the function of the esophagus, stomach, colon,pancreas and liver. In the small intestine, there may be subtle alterations in the intestinal morphology, as well as a decline in the uptake of fatty acids and sugars.The malabsorption may be partially reversed by aging glucagon-like peptide 2 (GLP2) or dexamethasone.Modifications in the type of lipids in the diet will influence the intestinal absorption of nutrients: for example, in mature rats a diet enriched with saturated as compared with polysaturated fatty acids will enhance lipid and sugar uptake, whereas in older animals the opposite effect is observed. Thus, the results of studies of the intestinal adaptation performed in mature rats does not necessarily apply in older animals. The age-associated malabsorption of nutrients that occurs with aging may be one of the several factors which contribute to the malnutrition that occurs with aging.

  7. Ageing in communal place

    DEFF Research Database (Denmark)

    Aarhus, Rikke; Ballegaard, Stinne Aaløkke; Grönvall, Erik;

    2009-01-01

    In this paper we adopt the position that design of social media for the elderly and virtual senior communities may be informed by studying `real´senior communities. Since current research efforts target the role of social media and virtual communities for supporting seniors ageing in place, i.e. in...

  8. Bioethics and aging

    OpenAIRE

    Domingo Castillo

    2012-01-01

    The purpose of this presentation is to discuss some concepts related to bioethics and ageing, specifically with regard to health and disease. Considerations on medical practice are made by referring to Kant and Heidelberg school of thought. Perception of time in the elderly and issues such as euthanasia and death are mentioned.

  9. Ageing management in Sweden

    International Nuclear Information System (INIS)

    Since the adoption of the 1997 act of parliament concerning the abolishment of nuclear power in Sweden plant lives are no longer limited until 2010 as they were following the referendum in 1980. The Swedish Nuclear Power Inspectorate (SKI) has therefore in its most recent general regulations from 2004 introduced requirements for nuclear power plants to develop ageing management programmes which should have been in place by the end of 2005. Since SKI:s role is not to provide detailed regulations but to ensure that the licensees take the full responsibility for the safety of their plants the detailed contents of the programmes have not been stipulated by SKI. An ageing management programme should coordinate the plant efforts in other programmes such as maintenance, monitoring, inspection, environmental qualification, chemistry, periodic testing and surveillance programmes that should already exist. In this way an integrated and long term approach to these issues can be ensured and become a natural part in the overall management of the plant. To this end it is important that the ageing management programme, as all other central programmes and processes, is documented in the quality assurance system, overall management system and is included in the underlying safety analysis report of the plant. Once the ageing management programmes have been established SKI is planning to assess them specifically through a combination of inspection and document reviews during 2008 and 2009. Thereafter it is anticipated that the major regulatory effort will be concentrated to the assessment of the periodic safety reviews to determine the effectiveness of the programmes and whether further specific regulatory action is required. SKI will also continue its active involvement in national and international research efforts to improve the understanding of ageing and degradation mechanisms. (author)

  10. 人口老龄化对我国经济社会发展的影响及对策%The Influence and Countermeasures of Population Aging on the Development of Economy and Society in China

    Institute of Scientific and Technical Information of China (English)

    薛凯

    2012-01-01

    人口老龄化是经济社会发展进步的重要标志,也给经济社会发展带来重大的影响和挑战。妥善应时人口老龄化的挑战,对深入贯彻落实科学发展观,实现可持续发展具有重要意义,也是落实以人为本,构建和谐社会的重要方面之一。多年来,我国经济的迅速发展为应对人口老龄化奠定了坚实的物质基础,现阶段应当以转变经济发展方式、加强和创新社会管理为重点,破解人口老龄化带来的经济社会难题。%Population aging is an important sign of progress in economy and society. However, it brings great influence and challenge to the development of economy and society. To deal with the challenge of population aging is of great importance to carry out scientific development concept and realize sustainable development. What is more, it is one of the important aspects of constructing people - oriented harmonious society. Over the years, the rapid development of Chinese economy provides solid foundation to deal with population aging. At present, China should conform the economic development mode to solve the problem of population aging.

  11. Aging men-Challenges ahead

    Institute of Scientific and Technical Information of China (English)

    Bruno Lunenfeld

    2001-01-01

    The prolongation of life expectancy and the drastic reduction of fertility rate are the primary cause of an aging world. It is projected that the elderly (above 65) will increase within the next 25 years by 82 %, whereas the new born only by 3 %. Despite the enormous medical progress during the past few decades, the last years of life are still accompanied by increasing ill health and disability. The ability to maintain active and independent living for as long as possible is a crucial factor for aging in health and dignity. Therefore, the promotion of healthy aging and the prevention of disability in men, must assume a central role in medical research and medical practice as well as in the formulation of national health and social policies. Effective programs promoting health and aging will ensure a more efficient use of health and social services and improve the quality of life in older persons by enabling them to remain independent and productive. The most important and drastic gender differences in aging are related to organs and or systems dependant or influenced by reproductive hormones. In distinction to the course of reproductive aging in women, with the rapid decline in sex hormones and expressed by the cessation of menses, aging men experience a slow and continuous decline of hormones. This decline in endocrine function involves: A decrease of testosterone, dehydroepiandrosterone (DHEA),oestrogens, thyroid stimulating hormone (TSH), growth hormone (GH), insulin-like growth factor-1 (IGF-1), and melatonin. This decrease is concomitant with an increase of LH and FSH. In addition sex hormone binding globulin's (SHBG) increase with age resulting in further lowering the concentrations of free biologically active androgens. Interventions such as hormone replacement therapy may prevent, delay or alleviate the debilitating conditions which may result from secondary partial endocrine deficiency. Primary and secondary preventive strategies such as the promotion of

  12. Perceived age as clinically useful biomarker of ageing: cohort study

    DEFF Research Database (Denmark)

    Christensen, Kaare; Thinggaard, Mikael; McGue, Matt;

    2009-01-01

    young men, and 11 older women (assessors); 1826 twins aged >or=70. MAIN OUTCOME MEASURES: Assessors: perceived age of twins from photographs. Twins: physical and cognitive tests and molecular biomarker of ageing (leucocyte telomere length). RESULTS: For all three groups of assessors, perceived age was...

  13. Adult Graduates' Negotiations of Age(ing) and Employability

    Science.gov (United States)

    Siivonen, Päivi; Isopahkala-Bouret, Ulpukka

    2016-01-01

    In this article, we will explore Finnish adult graduates' social positioning in relation to age and ageing, and the new discursive framing of employability that is firmly expressed in national as well as in European policy agendas. Age is here understood as a social construction and ageing as a lifelong process. We will analyse our joint interview…

  14. Aging trends -- the Philippines.

    Science.gov (United States)

    Biddlecom, A E; Domingo, L J

    1996-03-01

    This report presents a description of the trends in growth of the elderly population in the Philippines and their health, disability, education, work status, income, and family support. The proportion of elderly in the Philippines is much smaller than in other Southeast Asian countries, such as Singapore and Malaysia. The elderly population aged over 65 years increased from 2.7% of total population in 1990 to 3.6% in 1990. The elderly are expected to comprise 7.7% of total population in 2025. The proportion of elderly is small due to the high fertility rate. Life expectancy averages 63.5 years. The aged dependency ratio will double from 5.5 elderly per 100 persons aged 15-64 years in 1990 to 10.5/100 in 2025. A 1984 ASEAN survey found that only 11% of elderly rated their health as bad. The 1990 Census reveals that 3.9% were disabled elderly. Most were deaf, blind, or orthopedically impaired. 16% of elderly in the ASEAN survey reported not seeing a doctor even when they needed to. 54% reported that a doctor was not visited due to the great expense. In 1980, 67% of men and 76% of women aged over 60 years had less than a primary education. The proportion with a secondary education in 2020 is expected to be about 33% for men and 33% for women. 66.5% of men and 28.5% of women aged over 60 years were in the formal labor force in 1990. Women were less likely to receive cash income from current jobs or pensions. 65% of earnings from older rural people was income from agricultural production. 60% of income among urban elderly was from children, and 23% was from pensions. Family support is provided to the elderly in the form of coresidence. In 1988, 68% of elderly aged over 60 years lived with at least one child. Retirement or nursing homes are uncommon. The Philippines Constitution states that families have a duty to care for elderly members. PMID:12292274

  15. Biological psychological and social determinants of old age: bio-psycho-social aspects of human aging.

    Science.gov (United States)

    Dziechciaż, Małgorzata; Filip, Rafał

    2014-01-01

    The aging of humans is a physiological and dynamic process ongoing with time. In accordance with most gerontologists' assertions it starts in the fourth decade of life and leads to death. The process of human aging is complex and individualized, occurs in the biological, psychological and social sphere. Biological aging is characterized by progressive age-changes in metabolism and physicochemical properties of cells, leading to impaired self-regulation, regeneration, and to structural changes and functional tissues and organs. It is a natural and irreversible process which can run as successful aging, typical or pathological. Biological changes that occur with age in the human body affect mood, attitude to the environment, physical condition and social activity, and designate the place of seniors in the family and society. Psychical ageing refers to human awareness and his adaptability to the ageing process. Among adaptation attitudes we can differentiate: constructive, dependence, hostile towards others and towards self attitudes. With progressed age, difficulties with adjustment to the new situation are increasing, adverse changes in the cognitive and intellectual sphere take place, perception process involutes, perceived sensations and information received is lowered, and thinking processes change. Social ageing is limited to the role of an old person is culturally conditioned and may change as customs change. Social ageing refers to how a human being perceives the ageing process and how society sees it. PMID:25528930

  16. Natural radioactivity, age estimation

    International Nuclear Information System (INIS)

    The life in the earth depends totally on the sun. The universe was born from great explosion, the Big Bang. Practically all the materials in the nature contain radioactive nuclides. The sources that give them origin can be categorized as: 1. Cosmogenic s 2. primordial 3. anthropogenic. The application for the first and two groups of natural radionuclides it is the age estimation. Although some of the primitive ones has application in therapy of oncological patient. 1: The three groups of age estimation methods, for nuclear phenomenons are: 1. Measure of the radioactive decline of the primitive isotopes, by accumulation of stable isotopes. 2. use of the descendants of radioactive isotopes of the families of the Uranium or of the Th. 3. Measure of the cosmogenic s isotopes

  17. Aging management of Cirus

    International Nuclear Information System (INIS)

    Cirus, a 40 MWt tank type research reactor located at the Bhabha Atomic Research Centre, is in operation since 1960. In Cirus, heavy water is used as moderator, demineralized light water as primary coolant and natural uranium metal as fuel. The average availability factor had been about 70% till the year 1990 where after it started decreasing due to frequent problems with equipment and components. Systematic aging studies were therefore undertaken to assess the condition of structures, systems and components. Based on these studies, refurbishing requirements were identified and a detailed plan was drawn up for refurbishing. The reactor was shut down in October 1997 for execution of refurbishing jobs. A summary is presented of the results of aging studies and the refurbishing plans. Details of core unloading to facilitate refurbishing and some of the important jobs in the primary coolant system relating to pressure testing of primary coolant pipelines and repairs to identified leaky sections are discussed. (author)

  18. Aging, exercise, and attention.

    Science.gov (United States)

    Hawkins, H L; Kramer, A F; Capaldi, D

    1992-12-01

    The authors investigated the relationship among aging, attentional processes, and exercise in 2 experiments. First they examined age differences on 2 attentional tasks, a time-sharing task and an attentional flexibility task. Young adults alternated attention between 2 sequenced tasks more rapidly and time-shared the processing of 2 tasks more efficiently than older adults. They then investigated the effects of aerobic exercise on the same 2 attentional tasks in older adults. Following the 10-week exercise program, older exercisers showed substantially more improvement in alternation speed and time-sharing efficiency than older controls. Interestingly, this exercise effect was specific to dual-task processing. Both groups of subjects showed equivalent effects on single-task performance. These results indicate that aerobic exercise can exert a beneficial influence on the efficiency of at least 2 different attentional processes in older adults. PMID:1466833

  19. The Great Ice Age

    Science.gov (United States)

    Ray, Louis L.

    1992-01-01

    The Great Ice Age, a recent chapter in the Earth's history, was a period of recurring widespread glaciations. During the Pleistocene Epoch of the geologic time scale, which began about a million or more years ago, mountain glaciers formed on all continents, the icecaps of Antarctica and Greenland were more extensive and thicker than today, and vast glaciers, in places as much as several thousand feet thick, spread across northern North America and Eurasia. So extensive were these glaciers that almost a third of the present land surface of the Earth was intermittently covered by ice. Even today remnants of the great glaciers cover almost a tenth of the land, indicating that conditions somewhat similar to those which produced the Great Ice Age are still operating in polar and subpolar climates.

  20. Constipation in old age.

    LENUS (Irish Health Repository)

    Gallagher, Paul

    2009-01-01

    The prevalence of constipation increases with age. However, constipation is not a physiological consequence of normal ageing. Indeed, the aetiology of constipation in older people is often multifactorial with co-morbid diseases, impaired mobility, reduced dietary fibre intake and prescription medications contributing significantly to constipation in many instances. A detailed clinical history and physical examination including digital rectal examination is usually sufficient to uncover the causes of constipation in older people; more specialized tests of anorectal physiology and colonic transit are rarely required. The scientific evidence base from which to develop specific treatment recommendations for constipation in older people is, for the most part, slim. Constipation can be complicated by faecal impaction and incontinence, particularly in frail older people with reduced mobility and cognitive impairment; preventative strategies are important in those at risk.

  1. Blood rheology and aging

    OpenAIRE

    Başkurt, Oğuz K.; Simmonds, Michael J. ; Meiselman, Herbert J.

    2013-01-01

    Journal of Geriatric Cardiology (2013) 10: 291301 ©2013 JGC All rights reserved; www.jgc301.com http://www.jgc301.com; | Journal of Geriatric Cardiology Review  Open Access  Blood rheology and aging Michael J. Simmonds1, Herbert J. Meiselman2, Oguz K. Baskurt3 1Heart Foundation Research Centre, Griffith Health Institute, Griffith University, Gold Coast, QLD 4222, Australia 2Department of Physiology and Biophysics, Keck School of Medicine, University of S...

  2. Communication and Aging

    OpenAIRE

    Yorkston, Kathryn M.; Bourgeois, Michelle S.; Baylor, Carolyn R.

    2010-01-01

    Interpersonal communication has been described as a critical tool for life adjustment, linking people to their environment.1 When communication disorders are present these links can be easily broken. Communication disorders form a diverse group of conditions that vary in terms of type, severity, and co-occurrence with other symptoms that limit mobility, vision, endurance, or cognition. Although communication disorders affect people of all ages, the prevalence and complexity of these condition...

  3. Anthropocene Age Wicked Challenges

    DEFF Research Database (Denmark)

    Edgeman, Rick; Wu, Zhaohui

    2015-01-01

    weather events, drought, and desertification; threatened food supplies; water pollution, air pollution, and soil contamination; and the connection of these to disease, violence, and terrorism. Wicked challenges are discussed in relation to enterprise excellence, sustainability, resilience and robustness......Grand global challenges, including wicked human caused or influenced ones key to sustainability, characterize the Anthropocene Age. Among these are climate change driven by increased methane and CO2 in the atmosphere; consequent global warming and increasing intensity and incidence of extreme...

  4. The aging lung

    OpenAIRE

    Lowery EM; Brubaker AL; Kuhlmann E; Kovacs EJ

    2013-01-01

    Erin M Lowery,1 Aleah L Brubaker,2 Erica Kuhlmann,1 Elizabeth J Kovacs31Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine at Loyola University Medical Center, 2Loyola University Stritch School of Medicine, 3Department of Surgery, Loyola University Medical Center, Maywood, IL, USAAbstract: There are many age-associated changes in the respiratory and pulmonary immune system. These changes include decreases in the volume of the thoracic cavity, reduced lung volume...

  5. Diabetes in the Aged

    Science.gov (United States)

    Grobin, Wulf

    1970-01-01

    In keeping with the already known high prevalence of diabetes among residents of the Jewish Home for the Aged, Toronto, annual screening disclosed an average incidence of 25.5% of abnormal glucose tolerance (two-hour post-glucose blood sugars above 140 mg./100 ml.) in residents not known to be diabetic. Forty-five (47%) of the 94 residents with abnormal screening values were considered subsequently to be diabetic according to our criteria. Long-term follow-up, particularly of 81 residents initially normoglycemic in 1964-5, confirmed that the natural course of glucose tolerance in this population was one of progressive deterioration. By contrast, improvement amounting to remission has been demonstrated in nine out of 20 residents several years after they had been declared diabetic, and is thought to have been induced by dietotherapy. Moderate hyperglycemia per se did not cause symptoms in these almost always keto-resistant and usually aglycosuric aged diabetics, who often claimed they felt better when hyperglycemic. Hypoglycemia was an ever present danger when anti-diabetic medication was used; it was the main reason for undertreatment. So far, data from our long-term study have not shown morbidity to be markedly increased in the diabetics, and mortality was found to be evenly distributed among diabetic and non-diabetic male residents. However, in the females there was a clear correlation between mortality rate and the diminished glucose tolerance. What may appear as overdiagnosis of diabetes in the aged is recommended in the hope that early institution of dietary treatment will delay the development of clinical diabetes and the need for anti-diabetic agents. This, in turn, would prevent iatrogenic hypoglycemia. It would also reduce the severity and frequency of spontaneous hypoglycemia which, we believe, occurs more commonly in the early phase of diabetes in the aged than is generally realized. PMID:5476778

  6. HISTORICAL AND SOCIOLOGICAL ASPECTS OF BELIEF IN WEREWOLVES IN WESTERN EUROPEAN SOCIETY FROM THE LATE MIDDLE AGES-EARLY MODERN TIMES

    Directory of Open Access Journals (Sweden)

    O. I. Kholina

    2015-01-01

    Full Text Available Russian historiography in recent decades, there has been increased interest in the problems of everyday life in different historical periods and epochs. Regarding the middle ages and new time, an integral part of everyday life was the belief in the struggle between God and Devil, and Man in this confrontation was one of the conflicting parties. Holy Inquisition has been fighting with the followers of dark forces, witches and apostates – heretics since the XIII century. However, special attention should be paid to the fact that in addition to the above-mentioned victims of the ecclesiastical court, become and other devil's servants are werewolves. An important point is that the belief in creatures that can change their appearance, one way or another is present in all peoples of the world, but the massive scale, amounting to hysteria, she gets in Europe. According to the results of the research, the authors note that theories and facts that shaped the consciousness of man at the crossroads of two historical epochs – the middle ages and modern times, under the influence of Church ideologues and demonic studies, as well as reasoning of the average man which has been formed through the prism of perception of that time, belief in werewolves firmly occupies its own niche in daily life for a long time.

  7. Old age and poverty

    Directory of Open Access Journals (Sweden)

    Vuković Drenka

    2010-01-01

    Full Text Available The process of demographic changes in Serbia is followed by discussions on the need to provide safety at old age and solve the problems of poverty and social exclusion of older citizens. In the current state there are no mechanisms that guarantee an adequate life standard at old age, the consequence of which is a high poverty rate, deteriorating health and limited access to social programs. The results of the Survey on life standard from 2002 and 2007 show that poverty among population in general and pensioners has decreased, while the poverty risk among people older than 65 has increased twice. The restrictive methods of the reforms cause a change in the relation between the pensions and the earnings, so that more and more pensioners receive below average, i.e. minimal pensions. Not all old people are covered by pension insurance so that a significant number (around 400.000 does not have a safe monthly income at all. The state program of financial aid is of modest size and does not provide help to all of the poor. Welfare aid decreases the risk of poverty, but it do not guarantee an adequate level of material security at old age. The low level of minimal and average pensions, the decline of participation in the average earnings and the strict criteria of the social security system have brought to awareness the necessity of 'social pensions' and various help and support programs for the elderly. .

  8. The little ice age

    Energy Technology Data Exchange (ETDEWEB)

    Grove, J.M.

    1988-01-01

    The Little Ice Age, a period of glacier expansion in alpine regions that began sometime between the twelfth and sixteenth centuries and lasted until late in the nineteenth century, was recorded not only in glacial features dated by geologic techniques but also in historical documents such as field sketches, land values, and weather records, especially in the Alps. Indirect evidence of its impact in other parts of the world includes the records of sea-ice extent near Iceland and Greenland, the fate of the Viking settlements in Greenland, and many other suggestions that the climate was colder in the recent past than it is today. Jean Grove's book is an authoritative, superbly documented, and excellently written summary of the abundant evidence of climatic change during the last few centuries in the context of broader climatic variations of the last 10,000 years. This summary provides a much-needed perspective for considering the magnitude and frequency of natural climatic variations in the past, given predictions for the future. In the final chapter, Grove notes that natural climatic variations, including another minor ice age, might be expected in the future but at the end of the Little Ice Age coincided with the increased burning of fossil fuels during the industralization of Europe and North America. This coincidence does indeed suggest that modern scientists already have had a significant impact on the global climate.

  9. [Resilience in old age].

    Science.gov (United States)

    Cárdenas-Jiménez, Andrea; López-Díaz, Alba L

    2011-06-01

    The aim of this study was to characterise and analyse articles published on resilience and old-age from 1990-2006. After a systematic search of five databases (Academic Search Premier-Ebsco Host, Medline, Psyc Articles, Ovid and Science Direct) 33 pieces of literature were included in the analysis. The selected articles had 31 different definitions of resilience, from eight disciplines, mainly health-related fields. It was also found that the research studied the association of resilience with individual (68 variables) and social/environmental factors (17 variables); the most frequent were age and health self-perception. Cultural and religious values were of special interest amongst the latter variables. The literature review demonstrated that resilience in old age is a topic having increasing research interest; this has been linked to various individual, social and cultural factors. However, this is a rapidly developing area that requires that a unified definition be established and that a theoretical and intervention model be created. PMID:22031004

  10. Space age. Final report

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-05-01

    Space age had its world premiere at the large-screen Spaceport Theater at Cape Canaveral/Kennedy Spaceport. The first program was screened for invited guests who, that morning, also witnessed a launch of the Space Shuttle. Since that mission carried the first Japanese astronaut, it was a nice tie-in to the substantial co-production participation of space age by NHK Japan. A special press conference for the series and a twenty-minute preview reel was screened for journalists who were also at the Cape for the shuttle launch. Numerous first-hand newspaper articles were generated. CNN ran part of the preview reel. The first episode in the series, `The Quest for Planet Mars,` then ran twice a day for a week, prior to the Public Broadcasting Service broadcast on an Imax format screen at the Spaceport theater. The program was seen by thousands of visitors. Space age also had a special premier at the National Academy of Sciences in Washington, DC with some 400 special guests, including scientists and government agency representatives.

  11. Ageing changes in the eye

    OpenAIRE

    Salvi, S M; Akhtar, S; Currie, Z

    2006-01-01

    Ageing changes occur in all the structures of the eye causing varied effects. This article attempts to review the parameters of what is considered within the “normal limits” of ageing so as to be able to distinguish those conditions from true disease processes. Improving understanding of the ageing changes will help understand some of the problems that the ageing population faces.

  12. Immune Dysfunction in Aged Horses.

    Science.gov (United States)

    McFarlane, Dianne

    2016-08-01

    The aging process in people is associated with changes in adaptive and innate immune responses. Similar changes occur in aged horses. Age-related progressive impairment in the ability to respond to pathogen challenge and an increased inflammatory reactivity may predispose geriatric horses to many diseases of old age. Specific recommendations for immune modification of older horses, including an age-appropriate vaccination schedule, are not currently available. In addition, the effect of old age on risk of infectious disease is poorly documented. More work is needed to better understand the interactions of age on immunity, vaccine response, and disease risk in horses. PMID:27329495

  13. The aging male project

    Directory of Open Access Journals (Sweden)

    Farid Saad

    2001-06-01

    Full Text Available With an increasing life expectancy and a decreasing reproduction rate, the population structure changes. A Jenapharm R & D program investigates the endocrinology of aging men. In men, a decrease in production of sex steroids and other hormones with age can be observed. The typical patterns of daily rhythmicity become less distinct. This is part of a very complex picture in which not only isolated hormones are involved, but also the influence of hormones on each other. Many factors from the external and intemal environment mediated by neurotransmitters constantly affect the highly sensitive hormonal balance. Therefore, aging has also been defined as "the gradual dysfunction of homeostatic processes". Declining testosterone (T levels are involved in 'andropausal' symptoms in men: loss of libido, erectile dysfunction, insulin receptor resistance, obesity, osteoporosis, disturbances of lipid metabolism, myocardial and circulatory disturbances, impaired well-being and mood. Data are derived from studies in hypogonadal men treated by T replacement. In such parients under T treatment libido increases, fat mass decreases, muscle strenth, bone mineral density and erythropoesis increase. Whether the symptoms of andropause in aging men could successfully be treated by T substitution remains to be investigated. Negative effects of T, especially on the prostate and the cardiovascular system, are under discussion. There is increasing evidence that low T levels seem to be a risk factor for both the prostate and the cardiovascular system. Jenapharm's new testosterone undecanoate formulation for intramuscular injection can be administered every three months. T levels remain within the physiologic range. No supraphysiologic peaks occur. In women, estrogens have beneficial non-genital effects. Studies concentrate on synthetic estrogens for men without feminizing properties such as gynecomastia and reduced testicular size. Several derivatives of 17-

  14. Age aspects of habitability

    Science.gov (United States)

    Safonova, M.; Murthy, J.; Shchekinov, Yu. A.

    2016-04-01

    A `habitable zone' of a star is defined as a range of orbits within which a rocky planet can support liquid water on its surface. The most intriguing question driving the search for habitable planets is whether they host life. But is the age of the planet important for its habitability? If we define habitability as the ability of a planet to beget life, then probably it is not. After all, life on Earth has developed within only ~800 Myr after its formation - the carbon isotope change detected in the oldest rocks indicates the existence of already active life at least 3.8 Gyr ago. If, however, we define habitability as our ability to detect life on the surface of exoplanets, then age becomes a crucial parameter. Only after life had evolved sufficiently complex to change its environment on a planetary scale, can we detect it remotely through its imprint on the atmosphere - the so-called biosignatures, out of which the photosynthetic oxygen is the most prominent indicator of developed (complex) life as we know it. Thus, photosynthesis is a powerful biogenic engine that is known to have changed our planet's global atmospheric properties. The importance of planetary age for the detectability of life as we know it follows from the fact that this primary process, photosynthesis, is endothermic with an activation energy higher than temperatures in habitable zones, and is sensitive to the particular thermal conditions of the planet. Therefore, the onset of photosynthesis on planets in habitable zones may take much longer time than the planetary age. The knowledge of the age of a planet is necessary for developing a strategy to search for exoplanets carrying complex (developed) life - many confirmed potentially habitable planets are too young (orbiting Population I stars) and may not have had enough time to develop and/or sustain detectable life. In the last decade, many planets orbiting old (9-13 Gyr) metal-poor Population II stars have been discovered. Such planets had had

  15. Changing family structure and aging issues.

    Science.gov (United States)

    Bae, H

    1987-12-01

    Rapid industrialization, adaptation of modern values, and rural-urban migration in Korea have led to the replacement of the extended family with the nuclear of conjugal family. In 1980, 13% of Korean households were 1-generational, 70% were 2-generational, 17% were 3-generational and less than 1% were 4-generational. This trend has had serious implications for the aged, who have become increasingly isolated from Korean society. Hindering the adaptation of the aged to modern society are their low educational level, rural concentration, low income, and high rate of female members. Adult children who are well educated and prosperous economically are most likely to refuse to take responsibility for aged parents. Since some 23% of the aged currently live alone, Korean society must assume some of the responsibility that has traditionally been accepted by family members. There is a need for systematic programming that takes into account the current sociodemographic circumstances of Korea's aged population. Incentives such as tax exemptions and aged care allowances should be considered to encourage children to take responsibility for their aged parents. To meet the needs of the growing number of aged who are disabled and without family support, the number of geriatric hospitals and institutions must be expanded. Also important are supplementary programs such as housekeeping services, meals on wheels, and day care. Although the expansion of social welfare programs and institutions for the aged is essential, they can not in themselves meet the emotional needs of the aged that have traditionally been served by family connectedness. PMID:12315151

  16. Constructing third age eHealth consumers by using personas from a cultural age perspective

    NARCIS (Netherlands)

    Ekström, M.; Loos, E.F.

    2015-01-01

    Society ages and our already extensive use of a host of different portable devices continues to expand. No leap of the imagination is needed to grasp that an exponential growth of the eHealth market is at hand. While the ageing of the baby boomers will have an impact on the global economy as a whole

  17. Mathematical Model of Age Aggression

    OpenAIRE

    Golovinski, P. A.

    2013-01-01

    We formulate a mathematical model of competition for resources between representatives of different age groups. A nonlinear kinetic integral-differential equation of the age aggression describes the process of redistribution of resources. It is shown that the equation of the age aggression has a stationary solution, in the absence of age-dependency in the interaction of different age groups. A numerical simulation of the evolution of resources for different initial distributions has done. It ...

  18. AgeFactDB—the JenAge Ageing Factor Database—towards data integration in ageing research

    OpenAIRE

    Hühne, Rolf; Thalheim, Torsten; Sühnel, Jürgen

    2013-01-01

    AgeFactDB (http://agefactdb.jenage.de) is a database aimed at the collection and integration of ageing phenotype data including lifespan information. Ageing factors are considered to be genes, chemical compounds or other factors such as dietary restriction, whose action results in a changed lifespan or another ageing phenotype. Any information related to the effects of ageing factors is called an observation and is presented on observation pages. To provide concise access to the complete info...

  19. Interpreting spotted dolphin age distributions

    OpenAIRE

    Barlow, Jay; Hohn, Aleta A.

    1984-01-01

    Previous work has determined the age distribution from a sample of spotted dolphins (Stenella attenuata) killed in the eastern Pacific tuna purse-seine fishery. In this paper we examine the usefulness of this age distribution for estimating natural mortality rates. The observed age distribution has a deficiency of individuals from 5-15 years and cannot represent a stable age distribution. Sampling bias and errors in age interpretation are examined as possible causes of the "dip" in the obs...

  20. [Relationships among self concept, perception of aging and physical aging].

    Science.gov (United States)

    Lee, Y H; Kim, M S; Choi, Y H

    1988-12-01

    Although everyone grows old, perception about the aging process and aging as measured physiologically vary widely. Perceptions of aging have psychologically influence on physical aging. This study was to examine the relationships between, self-concept, perception of aging, and physical aging in the elderly and to contribute to the theory development which may direct nursing intervention to promote well-being of the aged. Subjects were 70 women residents of a nursing home for the elderly in Seoul. Data collection was done from May 15 to June 15, 1988 using interview schedules and mechanical instruments. The instruments were selected items from the Health Self Concept Scale developed by Jacox and Stewart for self concept, and Secord and Jourad's Body Cathexis Scale and Osgood's Semantic Differential Scale for perception of aging. Physical aging was measured by mechanical instruments, inspection, questions, and palpation. The data were analysed for mean, t-test, ANOVA, and Pearson Correlation Coefficient using an S.P.S.S computerized program. The results of the analysis were as follows. 1. The mean level of self concept for the subject group was 16.97 (SD = +/- 6.17) in a range from 6-30. The mean level of perception of aging was 39.6. (SD = +/- 6.51) in a range from 13-65. The mean level of physical aging was 14.09 (SD = +/- 2.05) in a range from 8-40. 2. Relationships among self-concept, perception of aging, and physical aging. 1) There was a positive relationship between self-concept and perception of aging (r = 0.4461, p = 0.000). 2) There was a negative relationship between physical aging and perception of aging (r = -0.2975, p = 0.006). 3) There was a tendency toward a negative relationship between physical aging and self-concept, but not a significant relationship (r = -0.1033, p = 0.197). 3. 1) No general characteristic variables were related to self concept. 2) The general characteristic variable related to the level of perception of aging was religion (t = 4

  1. Preschool psychopathology reported by parents in 23 societies: testing the seven-syndrome model of the child behavior checklist for ages 1.5-5

    DEFF Research Database (Denmark)

    Ivanova, Masha Y; Achenbach, Thomas M; Rescorla, Leslie A;

    2010-01-01

    To test the fit of a seven-syndrome model to ratings of preschoolers' problems by parents in very diverse societies.......To test the fit of a seven-syndrome model to ratings of preschoolers' problems by parents in very diverse societies....

  2. A Provocative Perspective on Population Aging and Old-Age Financial Protection

    OpenAIRE

    Holzmann, Robert

    2013-01-01

    Population aging is typically associated with economic challenges for productivity and financial threats for the old-age financial protection system of a country. This paper takes an optimistic position and outlines key ingredients to make it a successful experience. Yet to turn this challenge into an opportunity requires a significant change in a society's mindset and policies, such as recognizing that population aging and increased life expectancy are quite likely the biggest challenge to m...

  3. Dry aging of beef; Review.

    Science.gov (United States)

    Dashdorj, Dashmaa; Tripathi, Vinay Kumar; Cho, Soohyun; Kim, Younghoon; Hwang, Inho

    2016-01-01

    The present review has mainly focused on the specific parameters including aging (aging days, temperature, relative humidity, and air flow), eating quality (flavor, tenderness and juiciness), microbiological quality and economic (shrinkage, retail yields and cost) involved beef dry aging process. Dry aging is the process where beef carcasses or primal cuts are hanged and aged for 28 to 55 d under controlling environment conditions in a refrigerated room with 0° to 4 °C and with relative humidity of 75 to 80 %. However there are various opinions on dry aging procedures and purveyors of such products are passionate about their programs. Recently, there has been an increased interest in dry aging process by a wider array of purveyors and retailers in the many countries. Dry aging process is very costly because of high aging shrinkage (6 to15 %), trims loss (3 to 24 %), risk of contamination and the requirement of highest grades meat with. The packaging in highly moisture-permeable bag may positively impact on safety, quality and shelf stability of dry aged beef. The key effect of dry aging is the concentration of the flavor that can only be described as "dry-aged beef". But the contribution of flavor compounds of proteolysis and lipolysis to the cooked dry aged beef flavor is not fully known. Also there are limited scientific studies of aging parameters on the quality and palatability of dry aged beef. PMID:27200180

  4. Unmaking old age: political and cognitive formats of active ageing

    DEFF Research Database (Denmark)

    Lassen, Aske Juul; Moreira, Tiago

    2014-01-01

    different epistemes, models and forms used in the constitution of active ageing policies, the authors show how active ageing is not one coordinated set of policy instruments, but comes in different formats. In the WHO, active ageing configures individual lifestyle in order to expand the plasticity of ageing......, based on epidemiological and public health conventions. In the EU, active ageing reforms the retirement behaviour of populations in order to integrate the plasticity of ageing into the institutions, based on social gerontological and demographic conventions. These conventional arrangements are cognitive...

  5. Molecular Inflammation: Underpinnings of Aging and Age-related Diseases

    OpenAIRE

    Chung, Hae Young; Cesari, Matteo; Anton, Stephen; Marzetti, Emanuele; Giovannini, Silvia; Seo, Arnold Young; Carter, Christy; Yu, Byung Pal; Leeuwenburgh, Christiaan

    2008-01-01

    Recent scientific studies have advanced the notion of chronic inflammation as a major risk factor underlying aging and age-related diseases. In this review, low-grade, unresolved, molecular inflammation is described as an underlying mechanism of aging and age-related diseases, which may serve as a bridge between normal aging and age-related pathological processes. Accumulated data strongly suggest that continuous (chronic) up-regulation of pro-inflammatory mediators (e.g., TNF-α, IL-1β, 6, CO...

  6. School Starting Age and the Crime-Age Profile

    DEFF Research Database (Denmark)

    Landersø, Rasmus; Nielsen, Helena Skyt; Simonsen, Marianne

    2015-01-01

    This paper uses register-based data to investigate the effects of school starting age on crime. Through this, we provide insights into the determinants of crime-age profiles. We exploit that Danish children typically start first grade in the calendar year they turn seven, which gives rise to a...... discontinuity in school starting age for children born around New Year. Our analysis speaks against a simple invariant crime-age profile as is popular in criminology: we find that higher school starting age lowers the propensity to commit crime at young ages. We also find effects on the number of crimes...

  7. The new electricity age

    Energy Technology Data Exchange (ETDEWEB)

    Weinhold, Michael; Willnow, Klaus

    2010-09-15

    A sustainable energy system requires optimal integration of all components resulting in an integrated energy system. To setup the integrated energy system three steps have to be completed: 1. Optimal selection and allocation of the Energy Mix 2. Efficiency increase along all steps of the energy conversion chain 3. Holistic optimization across infrastructures and across regions using Smart Grid Technologies Due to greater complexity caused by growing demand for electricity and decentralized generation only end-to-end intelligence from power plants via networks to end-use applications, so-called smart grid technologies will enable the integrated energy system and thus the New Electricity Age.

  8. Ageing in Communal Place

    DEFF Research Database (Denmark)

    Aarhus, Rikke; Ballegaard, Stinne Aaløkke; Grönvall, Erik;

    2009-01-01

    In this paper we adopt the position that design of social media for the elderly and virtual senior communities may be informed by studying ‘real’ senior communities. Since current research efforts target the role of social media and virtual communities for supporting seniors ageing in place, i...... how these findings apply to designers of social media technologies. .......e. in their homes, housing communities seem a natural place to begin this enquiry. We conducted observations and informal interviews in six different senior dwellings. In this paper we present the key findings from these visits related to social interaction and the formation of communities and explicate...

  9. Check valves aging assessment

    International Nuclear Information System (INIS)

    In support of the NRC Nuclear Plant Aging Research (NPAR) program, the Oak Ridge National Laboratory (ORNL) has carried out an assessment of several check value diagnostic monitoring methods, in particular, those based on measurements of acoustic emission, ultrasonics, and magnetic flux. The evaluations have focussed on the capabilities of each method to provide information useful in determining check valve aging and service wear effects, check valve failures, and undesirable operating modes. This paper describes the benefits and limitations associated with each method and includes recent laboratory and field test data, including data obtained from the vendors who recently participated in a comprehensive series of tests directed by a nuclear industry users group. In addition, as part of the ORNL Advanced Diagnostic Engineering Research and Development Center (ADEC), two novel nonintrusive monitoring methods were developed that provide several unique capabilities. These methods, based on external ac- an dc-magnetic monitoring are also described. None of the examined methods could, by themselves, monitor both the instantaneous position and motion of check valve internals and valve leakage; however, the combination of acoustic emission monitoring with one of the other methods provides the means to determine vital check valve operational information

  10. [Feeding and aging].

    Science.gov (United States)

    Sánchez Zaplana, Isabel; Maestre González, Elena

    2013-06-01

    Aging is characterized by an increase in relative population of 65 years and older, and can say that, in our country, it is a phenomenon demographic, political, social and health. Several studies have shown that the nutritional status of the general population and the elderly, in particular, is a valid indicator to predict longevity and quality of life of this group of people. The World Health Organization (who) pointed out that the elderly population is a group nutritionally very vulnerable as a result of anatomical and physiological changes associated with aging. Between 35-40 of the elderly has some kind of altered nutrition or malnutrition: protein or protein-energy malnutrition, selective deficiency of vitamins and minerals, inadequate water intake, obesity, etc. The best way to promote the quality of life and prevent disease is a proper diet, also called healthy eating, adapted to the special circumstances which older persons may present without forgetting gastronomy is not incompatible with health. In this article, some tips are also available for preparing and cooking food, as well as culinary strategies to introduce them in the daily menu. PMID:23909217

  11. Aging in language dynamics.

    Directory of Open Access Journals (Sweden)

    Animesh Mukherjee

    Full Text Available Human languages evolve continuously, and a puzzling problem is how to reconcile the apparent robustness of most of the deep linguistic structures we use with the evidence that they undergo possibly slow, yet ceaseless, changes. Is the state in which we observe languages today closer to what would be a dynamical attractor with statistically stationary properties or rather closer to a non-steady state slowly evolving in time? Here we address this question in the framework of the emergence of shared linguistic categories in a population of individuals interacting through language games. The observed emerging asymptotic categorization, which has been previously tested--with success--against experimental data from human languages, corresponds to a metastable state where global shifts are always possible but progressively more unlikely and the response properties depend on the age of the system. This aging mechanism exhibits striking quantitative analogies to what is observed in the statistical mechanics of glassy systems. We argue that this can be a general scenario in language dynamics where shared linguistic conventions would not emerge as attractors, but rather as metastable states.

  12. Smoking and cognitive change from age 11 to age 80

    OpenAIRE

    Deary, Ian J; Pattie, Alison; M. D. Taylor; Whiteman, Martha C; Starr, John M; Lawrence J Whalley

    2003-01-01

    Age related cognitive decline affects people’s quality of life and their ability to live independently. A recent review stated, "[we] are aware of no studies on the relationship between smoking and cognitive decline associated with normal aging or studies of the effect of smoking on cognition in normally aging individuals." Some previous studies examined smoking in relation to pathological cognitive aging, but lacked cognitive data before the initiation of smoking, and used crude clinical cog...

  13. Perceived age as a biomarker of ageing: a clinical methodology

    DEFF Research Database (Denmark)

    Gunn, David A; Murray, Peter G; Tomlin, Cyrena C;

    2008-01-01

    facial ageing is detailed. The methodology utilises facial photographs of subjects to present images to large numbers of age assessors who are primarily nationals of the country of study origin. In five observational studies in five different countries involving 874 female subjects it was found that...... measure when large numbers of adult age assessors are used and can be utilised globally in studies to investigate facial ageing....

  14. 一部从哲学的高度探讨应对人口老龄化的力作——谈《老龄社会的革命》%A Masterpiece Discussion of Coping with Population Aging from the Height of Philosophy—— Talk about the Revolution of Aging Society

    Institute of Scientific and Technical Information of China (English)

    邬沧萍

    2015-01-01

    The Revolution of the Ageing Society is a masterpiece which discuss coping with population aging from the height of philosophy. The book points out that China's thinking and policy of response to population aging should be combined with the macroscopical arrangement of the socialist economy, politics, culture, society and ecological construction, and it should take a long-term view and precautions. The book has detailed materials and explains profound theories in simple languages. This book has the following light spots in aging theories: it puts forward that it is worth discussing moderate aging in science; under the background of population aging, the consideration of the meaning and value of life has important theoretical signiifcance and practical significance; it puts forward that age equal theory should be fully aware theoretically; seeing ifnancial industry as the important condition of sustainable development of an aging society has great theoretical value; it puts forward some ideas which can help people know the essence of pension problem during expounding these problems; it attaches great importance to long-term care in the maintenance of health; it stresses the important role of family and spreads the theory that respect and love the old man all over the world has important ethical and moral values; and it does researches on aging in the international perspective.%《老龄社会的革命》是一部从哲学的高度探讨应对人口老龄化的力作.书中指出,中国应对人口老龄化的思维和政策,要有同社会主义经济、政治、文化、社会、生态建设相结合的宏观布局,要高瞻远瞩,未雨绸缪.全书资料翔实,深入浅出.在老龄理论上,本书具有如下亮点:提出适度老龄化的论点在科学上是有讨论价值的;在人口老龄化背景下,重提必须考虑人生的意义和价值,有着重要的理论意义和现实意义;提出年龄平等理念,在理论上是应该充分认识的;把金融

  15. Employment Age Discrimination on Women

    Institute of Scientific and Technical Information of China (English)

    黄捧

    2015-01-01

    Employment age discrimination against women is not an unusual phenomenon in China.Through describing the present situation and negative effect of this phenomenon,this paper claims laws are very important weapon to eliminate age discrimination against women.

  16. Aging changes in the senses

    Science.gov (United States)

    ... ency/article/004013.htm Aging changes in the senses To use the sharing features on this page, ... enable JavaScript. As you age, the way your senses (hearing, vision, taste, smell, touch) give you information ...

  17. Aging changes in body shape

    Science.gov (United States)

    ... and both sexes. Height loss is related to aging changes in the bones, muscles, and joints. People ... lifetime. Your lifestyle choices affect how quickly the aging process takes place. Some things you can do ...

  18. Aging changes in hormone production

    Science.gov (United States)

    ... that produce hormones are controlled by other hormones. Aging also changes this process. For example, an endocrine ... produce the same amount at a slower rate. AGING CHANGES The hypothalamus is located in the brain. ...

  19. Large for gestational age (LGA)

    Science.gov (United States)

    ... this page: //medlineplus.gov/ency/article/002248.htm Large for gestational age (LGA) To use the sharing features on this page, please enable JavaScript. Large for gestational age means that a fetus or ...

  20. MedlinePlus: Healthy Aging

    Science.gov (United States)

    ... Health screening - women - over 65 Related Health Topics Exercise for Seniors Nutrition for Seniors Seniors' Health National Institutes of Health The primary NIH organization for research on Healthy Aging is the National Institute on Aging Languages ...

  1. Personality Plasticity After Age 30

    Science.gov (United States)

    Terracciano, Antonio; Costa, Paul T.; McCrae, Robert R.

    2009-01-01

    Rank-order consistency of personality traits increases from childhood to age 30. After that, different summaries of the literature predict a plateau at age 30, or at age 50, or a curvilinear peak in consistency at age 50. These predictions were evaluated at group and individual levels using longitudinal data from the Guilford-Zimmerman Temperament Survey and the Revised NEO Personality Inventory over periods of up to 42 years. Consistency declined toward a non-zero asymptote with increasing time-interval. Although some scales showed increasing stability after age 30, the rank-order consistencies of the major dimensions and most facets of the Five-Factor Model were unrelated to age. Ipsative stability, assessed with the California Adult Q-Set, was also unrelated to age. These data strengthen claims of predominant personality stability after age 30. PMID:16861305

  2. Organizational Climate for Successful Aging.

    Science.gov (United States)

    Zacher, Hannes; Yang, Jie

    2016-01-01

    Research on successful aging at work has neglected contextual resources such as organizational climate, which refers to employees' shared perceptions of their work environment. We introduce the construct of organizational climate for successful aging (OCSA) and examine it as a buffer of the negative relationship between employee age and focus on opportunities (i.e., beliefs about future goals and possibilities at work). Moreover, we expected that focus on opportunities, in turn, positively predicts job satisfaction, organizational commitment, and motivation to continue working after official retirement age. Data came from 649 employees working in 120 companies (M age = 44 years, SD = 13). We controlled for organizational tenure, psychological climate for successful aging (i.e., individuals' perceptions), and psychological and organizational age discrimination climate. Results of multilevel analyses supported our hypotheses. Overall, our findings suggest that OCSA is an important contextual resource for successful aging at work. PMID:27458405

  3. Cognition and brain functional aging

    Directory of Open Access Journals (Sweden)

    Hui-jie LI

    2014-03-01

    Full Text Available China has the largest population of elderly adults. Meanwhile, it is one of the countries showing fastest aging speed in the world. Aging processing is always companied with a series of brain structural and functional changes, which result in the decline of processing speed, working memory, long-term memory and executive function, etc. The studies based on functional magnetic resonance imaging (fMRI found certain aging effects on brain function activation, spontaneous activity and functional connectivity in old people. However, few studies have explored the brain functional curve during the aging process while most previous studies explored the differences in the brain function between young people and old people. Delineation of the human brain functional aging curve will promote the understanding of brain aging mechanisms and support the normal aging monitoring and early detection of abnormal aging changes. doi: 10.3969/j.issn.1672-6731.2014.03.005

  4. Aging changes in the breast

    Science.gov (United States)

    ... this page: //medlineplus.gov/ency/article/003999.htm Aging changes in the breast To use the sharing ... chap 18. Minaker KL. Common clinical sequelae of aging. In: Goldman L, Schafer AI, eds. Goldman's Cecil ...

  5. Aging changes in the lungs

    Science.gov (United States)

    ... this page: //medlineplus.gov/ency/article/004011.htm Aging changes in the lungs To use the sharing ... out (exhaled). Watch this video about: Gas exchange AGING CHANGES IN YOUR BODY AND THEIR AFFECTS ON ...

  6. Aging changes in body shape

    Science.gov (United States)

    ... this page: //medlineplus.gov/ency/article/003998.htm Aging changes in body shape To use the sharing ... and both sexes. Height loss is related to aging changes in the bones, muscles, and joints. People ...

  7. 7 Steps to Aging Well

    Science.gov (United States)

    ... Issue Past Issues Special Section 7 Steps to Aging Well Past Issues / Winter 2007 Table of Contents ... Exercise: A Guide from the National Institute on Aging is a publication from NIA that has strength, ...

  8. Aging changes in the kidneys

    Science.gov (United States)

    ... this page: //medlineplus.gov/ency/article/004010.htm Aging changes in the kidneys and bladder To use ... in the reproductive system can affect bladder control. Aging Changes and Their Effects on the Kidneys and ...

  9. Aging changes in hormone production

    Science.gov (United States)

    ... this page: //medlineplus.gov/ency/article/004000.htm Aging changes in hormone production To use the sharing ... that produce hormones are controlled by other hormones. Aging also changes this process. For example, an endocrine ...

  10. Personality plasticity after age 30.

    Science.gov (United States)

    Terracciano, Antonio; Costa, Paul T; McCrae, Robert R

    2006-08-01

    Rank-order consistency of personality traits increases from childhood to age 30. After that, different summaries of the literature predict a plateau at age 30, or at age 50, or a curvilinear peak in consistency at age 50. These predictions were evaluated at group and individual levels using longitudinal data from the Guilford-Zimmerman Temperament Survey and the Revised NEO Personality Inventory for periods of up to 42 years. Consistency declined toward a nonzero asymptote with increasing time interval. Although some scales showed increasing stability after age 30, the rank-order consistencies of the major dimensions and most facets of the Five-Factor Model were unrelated to age. Ipsative stability, assessed with the California Adult Q-Set, also was unrelated to age. These data strengthen claims of predominant personality stability after age 30. PMID:16861305

  11. Nutrition and aging.

    Science.gov (United States)

    Noel, Mary; Reddy, Mohan

    2005-09-01

    Nutritional concerns are common among older adults seen in the primary care office. The food pyramid for people over the age of 70 years is a useful starting point for discussions about what reasonably healthy older adults should be eating and drinking. If there is a decline in the ability to perform IADLs or if there is a decrease in appetite or the discovery of unintended weight loss, careful assessment followed by targeted interventions may improve health outcomes and the quality of life. Restrictive diets are often not well tolerated, especially by frail older adults. Dietary recommendations blending the elements of the pyramid and the essential components of accepted medical nutritional therapy that are most consistent with the patient's lifelong eating patterns are most likely to succeed. PMID:16140121

  12. Analyzing an Aging ISS

    Science.gov (United States)

    Scharf, R.

    2014-01-01

    The ISS External Survey integrates the requirements for photographic and video imagery of the International Space Station (ISS) for the engineering, operations, and science communities. An extensive photographic survey was performed on all Space Shuttle flights to the ISS and continues to be performed daily, though on a level much reduced by the limited available imagery. The acquired video and photo imagery is used for both qualitative and quantitative assessments of external deposition and contamination, surface degradation, dynamic events, and MMOD strikes. Many of these assessments provide important information about ISS surfaces and structural integrity as the ISS ages. The imagery is also used to assess and verify the physical configuration of ISS structure, appendages, and components.

  13. Glycoconjugate changes in aging and age-related diseases.

    Science.gov (United States)

    Ando, Susumu

    2014-01-01

    The significance of glycosphingolipids and glycoproteins is discussed in their relation to normal aging and pathological aging, aging with diseases. Healthy myelin that looks stable is found to be gradually degraded and reconstructed throughout life for remodeling. An exciting finding is that myelin P0 protein is located in neurons and glycosylated in aging brains. In pathological aging, the roles of glycosphingolipids and glycoproteins as risk factors or protective agents for Alzheimer's and Parkinson's diseases are discussed. Intensive studies have been performed aiming to remove the risks from and to restore the functional deficits of the brain. Some of them are expected to be translated to therapeutic means. PMID:25151390

  14. Radiation and aging

    International Nuclear Information System (INIS)

    Dorsal root ganglia (DRG) specimens were obtained from 3 women aged in their 6th decade and 5 men in their 8th decade, who were exposed to A-bomb at ≤ 3,000 m from the hypocenter in Nagasaki, and were analyzed for the frequency of DRG neurons with lipofuscin (LP), neuromelanin (NM), and eosinophilic granule (EG). The neurons for the men in the A-bomb group showed an increase of LP and a decrease of NM compared with those in age- and sex-matched control group, with significant differences (p < 0.05 and p < 0.01). The frequency of neurons with EG tended to be slightly higher for the men in the A-bomb group than in the control group; however, this was not statistically significant. For the women, there was a tendency toward a higher frequency of neurons with LP in the A-bomb group than in the control group, although no statistically significant difference emerged from this limited material. Regarding NM and EG for the women, DRG neurons showed no significant difference between the groups. Both men and women showed similar trends for the frequency of DRG neurons without pigments; no significant difference was observed between the groups. Regarding the sum of DRG neurons with large amounts of LP and with mixed LP and EG, the frequency of neurons was significantly higher for the men in the A-bomb group than in the control group, although this was not significant for the women. (Namekawa, K.)

  15. Age-related oral changes.

    LENUS (Irish Health Repository)

    Mckenna, Gerald

    2010-10-01

    Age-related oral changes are seen in the oral hard and soft tissues as well as in bone, the temporomandibular joints and the oral mucosa. As older patients retain their natural teeth for longer, the clinical picture consists of normal physiological age changes in combination with pathological and iatrogenic effects. Clinical Relevance: With an ageing population retaining more of its natural teeth for longer, dental professionals should expect to observe oral age changes more frequently.

  16. Farmer Productivity at Various Ages

    OpenAIRE

    Tauer, Loren W.

    1993-01-01

    The productivity of farmers at six different age cohorts was computed by estimating production functions using 1987 census data. The results suggest that farmers of different ages operate with slightly different technologies and use various inputs at different efficiencies. Compared with previous 1978 estimates, the productivity of middleaged farmers appears to be even greater than the productivity of younger and older farmers. The average age of U.S. farmers exceeds the age of highest produc...

  17. Aging and Functional Brain Networks

    OpenAIRE

    Tomasi, Dardo; Volkow, Nora D.

    2011-01-01

    Aging is associated with changes in human brain anatomy and function and cognitive decline. Recent studies suggest the aging decline of major functional connectivity hubs in the “default-mode” network (DMN). Aging effects on other networks, however, are largely unknown. We hypothesized that aging would be associated with a decline of short- and long-range functional connectivity density (FCD) hubs in the DMN. To test this hypothesis we evaluated resting-state datasets corresponding to 913 hea...

  18. The clinical pharmacology of ageing

    OpenAIRE

    Swift, C G

    2003-01-01

    The ageing of populations and individuals continues to be as vital, yet to some extent as neglected, a topic in pharmacology and therapeutics as was first realised about 30 years ago. In parallel with the realisation of the predicted demographic shifts in both the developed and developing world, there have since been major developments in the basic biological concepts of ageing, in the physiology of ageing, in the study of pathogenetic mechanisms underlying a variety of age-associated disorde...

  19. Lithuanian Population Aging Factors Analysis

    OpenAIRE

    Agnė Garlauskaitė; Rasa Zabarauskaitė

    2015-01-01

    The aim of this article is to identify the factors that determine aging of Lithuania’s population and to assess the influence of these factors. The article shows Lithuanian population aging factors analysis, which consists of two main parts: the first describes the aging of the population and its characteristics in theoretical terms. Second part is dedicated to the assessment of trends that influence the aging population and demographic factors and also to analyse the determinants of the agin...

  20. Personality Plasticity After Age 30

    OpenAIRE

    Terracciano, Antonio; Costa, Paul T.; McCrae, Robert R.

    2006-01-01

    Rank-order consistency of personality traits increases from childhood to age 30. After that, different summaries of the literature predict a plateau at age 30, or at age 50, or a curvilinear peak in consistency at age 50. These predictions were evaluated at group and individual levels using longitudinal data from the Guilford-Zimmerman Temperament Survey and the Revised NEO Personality Inventory over periods of up to 42 years. Consistency declined toward a non-zero asymptote with increasing t...

  1. Bone age in cerebral palsy

    OpenAIRE

    Miranda, Eduardo Régis de Alencar Bona; Palmieri, Maurício D'arc; de Assumpção, Rodrigo Montezuma César; Yamada, Helder Henzo; Rancan, Daniela Regina; Fucs, Patrícia Maria de Moraes Barros

    2013-01-01

    Objective To compare the chronological age and bone age among cerebral palsy patients in the outpatient clinic and its correlation with the type of neurological involvement, gender and functional status. Methods 401 patients with spastic cerebral palsy, and ages ranging from three months to 20 years old, submitted to radiological examination for bone age and analyzed by two independent observers according Greulich & Pyle. Results In the topographic distribution, there was a significant delay (p

  2. Pathophysiology of ageing, longevity and age related diseases

    Directory of Open Access Journals (Sweden)

    Santoni Angela

    2007-08-01

    Full Text Available Abstract On April 18, 2007 an international meeting on Pathophysiology of Ageing, Longevity and Age-Related Diseases was held in Palermo, Italy. Several interesting topics on Cancer, Immunosenescence, Age-related inflammatory diseases and longevity were discussed. In this report we summarize the most important issues. However, ageing must be considered an unavoidable end point of the life history of each individual, nevertheless the increasing knowledge on ageing mechanisms, allows envisaging many different strategies to cope with, and delay it. So, a better understanding of pathophysiology of ageing and age-related disease is essential for giving everybody a reasonable chance for living a long and enjoyable final part of the life.

  3. Age-specific labor market dynamics

    NARCIS (Netherlands)

    Gielen, A. C.

    2008-01-01

    One important finding concerns the fact that job separations for older workers constitute mostly a one-way exit out of the labor force, despite the fact that an ageing society calls for an active labor market participation from us all. Also, the allocation of labor for younger workers has shown to b

  4. [Vitamin E in the aged].

    Science.gov (United States)

    Pentimone, F; del Corso, L; Laghi, G

    1994-06-01

    Aging is a multifactorial process still incompletely known. The role of oxidative damage to cell membranes, as an important phase of the process, is underlined by the recent literature. We emphasize the value of vitamin E as an antioxidant agent supplied by suitable diets in middle age and by cheap tablets in the aged. PMID:8001337

  5. Modern biological theories of aging

    International Nuclear Information System (INIS)

    These proceedings contain 30 papers grouped under the headings of: Theories of aging: A perspective; Evolution of life span in placental mammals; Developmentally programmed aging; Free-radical damage; Error catastrophe; DNA Damage and repair; and Organ systems as pacemakers of aging

  6. Is the Age Problem Resolved?

    Indian Academy of Sciences (India)

    Ali Akbar Navabi; Nematollah Riazi

    2003-03-01

    The cosmological, astrophysical, and nucleocosmochronological methods for estimating the age of the universe and the corresponding uncertainties are comparatively studied in the present paper.We are led to the conclusion that the newmeasurements of cosmological parameters, and the recent estimates of the age of globular clusters have led to the gradual disappearance of the age problem from the arena of modern cosmology.

  7. Ageing management for research reactors

    International Nuclear Information System (INIS)

    During the past several years, ageing of research reactor facilities continues to be an important safety issue. Despite the efforts exerted by operating organizations and regulatory authorities worldwide to address this issue, the need for an improved strategy as well as the need for establishing and implementing a systematic approach to ageing management at research reactors was identified. This paper discusses, on the basis of the IAEA Safety Standards, the effect of ageing on the safety of research reactors and presents a proactive strategy for ageing management. A systematic approach for ageing management is developed and presented together with its key elements, along with practical examples for their application. (author)

  8. Age determination and geological studies

    International Nuclear Information System (INIS)

    Two hundred and eight potassium-argon age determinations carried out on Canadian rocks and minerals are reported. Each age determination is accompanied by a description of the rock and mineral concentrate used; brief interpretative comments regarding the geological significance of each age are also provided where possible. The experimental procedures employed are described in brief outline and the constants used in the calculation of ages are listed. Two geological time-scales are reproduced in tabular form for ready reference and an index of all Geological Survey of Canada K-Ar age determinations published in this format has been prepared using NTS quadrangles as the primary reference

  9. Technical approach to aging management

    International Nuclear Information System (INIS)

    Systematic and effective control of age-related degradation of safety-related components, systems, and structures in nuclear power plants (NPPs) is an important challenge to plant operators. Several data bases, available to provide guidance on aging management, are summarized. However, the ultimate consideration is: How effectively is aging management being implemented at individual plants? Illustrated here is a specific strategy that served to develop the technical data base for the Nuclear Plant Aging Research Program. The strategy is comprehensive, systematic, and adaptable. Effective aging management at NPPs could be facilitated by a parallel strategy. The elements of a strategy are suggested

  10. Skin aging and oxidative stress

    Directory of Open Access Journals (Sweden)

    Sayeeda Ahsanuddin

    2016-05-01

    Full Text Available Skin aging occurs through two main pathways, intrinsic and extrinsic. These pathways have significant interaction in contributing to the aging phenotype, which includes skin laxity, wrinkling, pigmentation irregularities, and the appearance of neoplastic skin lesions. Here, we review the critical role that oxidative stress plays in skin aging, including its effects on signaling pathways involved in skin matrix formation and degradation, proteasome activity, as well as DNA structure. Furthermore, we discuss the recent literature surrounding the prevention and treatment of skin aging. Although current research is suggestive of the role of antioxidants in anti-aging skin therapies, further research is much needed to explore its role in humans.

  11. Deuteronation and aging.

    Science.gov (United States)

    Olgun, Abdullah; Oztürk, Kamile; Bayir, Selda; Akman, Serif; Erbil, M Kemal

    2007-04-01

    Deuterium has one proton and one neutron in its atomic nucleus, but hydrogen has only proton. The natural abundance of deuterium is 1 per approximately 6600 hydrogen atoms. Therefore deuterated water (both HOD + D(2)O [heavy water]) abundance is 1 per approximately 3300 water molecules. One dissociation product of deuterated and heavy water is deuteron (proton + neutron, D(+), H(2)OD(+)/D(3)O(+)). Because heavy water has a lower ionization constant than water, the D(+)/H(+) ratio is approximately 1/15,000 in biological fluids. O-D bond length is shorter than O-H, and D-O-D angle is lesser than H-O-H. Once a deuteron exchanges with proton on the water-exposed surface of a macromolecule, it can lead to a conformational change and the reverse exchange will be less likely. Deuteron bonds are stronger than proton bonds. Therefore an increase of deuteronated macromolecules can be expected in due course of time. In order to test this hypothesis, we conducted a pilot study and measured the D/H ratio in the tails of three Sprague-Dawley rats at different ages (4 weeks, 5 weeks, and >1-year old) by elemental analysis coupled with isotope ratio mass spectrometry (EA-IRMS) technique. To prevent the effect of daily water consumption, the homogenized tails were lyophilized before analysis. The results, as mean of several measurements, of 4 weeks, 5 weeks, and >1-year-old rats were per thousand-94 +/- 9.56, per thousand-101.71 +/- 6.89, per thousand-83.68 +/- 3.46 delta((2)H) relative to VSMOW, respectively. Although there is a slight increase in >1-year-old rat, the difference among the animals was not significant. We propose that, before reaching to a final conclusion about the accumulation of deuterium with aging, the measurements should be done not in whole tissue samples but in purified macromolecules from a larger set of animals. PMID:17460204

  12. Health screening - women - over age 65

    Science.gov (United States)

    Health maintenance visit - women - over age 65; Physical exam - women - over age 65; Yearly exam - women - over age 65; Checkup - women - over age 65; Women's health - over age 65; Preventive care exam - women - over ...

  13. Health screening - men - ages 40 to 64

    Science.gov (United States)

    Health maintenance visit - men - ages 40 to 64; Physical exam - men - ages 40 to 64; Yearly exam - ... 64; Checkup - men - ages 40 to 64; Men's health - ages 40 to 64; Preventive care - men - ages ...

  14. Health screening - women - ages 40 to 64

    Science.gov (United States)

    Health maintenance visit - women - ages 40 to 64; Physical exam - women - ages 40 to 64; Yearly exam - ... 64; Checkup - women - ages 40 to 64; Women's health - ages 40 to 64; Preventive care - women - ages ...

  15. Health screening - women - ages 18 to 39

    Science.gov (United States)

    Health maintenance visit - women - ages 18 to 39; Physical exam - women - ages 18 to 39; Yearly exam - ... 39; Checkup - women - ages 18 to 39; Women's health - ages 18 to 39; Preventive care - women - ages ...

  16. Health screening - men age 65 and older

    Science.gov (United States)

    Health maintenance visit - men - over age 65; Physical exam - men - over age 65; Yearly exam - men - over age 65; Checkup - men - over age 65; Men's health - over age 65; Preventive care exam - men - over ...

  17. Quantifying the shape of aging

    DEFF Research Database (Denmark)

    Wrycza, Tomasz F; Missov, Trifon I; Baudisch, Annette

    2015-01-01

    aging rates, suggest the shape of aging as a novel and valuable alternative concept for comparative aging research. The concept of shape captures the direction and degree of change in the force of mortality over age, which—on a demographic level—reflects aging. We 1) provide a list of shape properties...... that are desirable from a theoretical perspective, 2) suggest several demographically meaningful and non-parametric candidate measures to quantify shape, and 3) evaluate performance of these measures based on the list of properties as well as based on an illustrative analysis of a simple dataset. The...... shape measures suggested here aim to provide a general means to classify aging patterns independent of any particular mortality model and independent of any species-specific time-scale. Thereby they support systematic comparative aging research across different species or between populations of the same...

  18. Exercise and the Aging Endothelium

    Directory of Open Access Journals (Sweden)

    Saeid Golbidi

    2013-01-01

    Full Text Available The endothelium plays a critical role in the maintenance of cardiovascular health by producing nitric oxide and other vasoactive materials. Aging is associated with a gradual decline in this functional aspect of endothelial regulation of cardiovascular homeostasis. Indeed, age is an independent risk factor for cardiovascular diseases and is in part an important factor in the increased exponential mortality rates from vascular disease such as myocardial infarction and stroke that occurs in the ageing population. There are a number of mechanisms suggested to explain age-related endothelial dysfunction. However, recent scientific studies have advanced the notion of oxidative stress and inflammation as the two major risk factors underlying aging and age-related diseases. Regular physical activity, known to have a favorable effect on cardiovascular health, can also improve the function of the ageing endothelium by modulating oxidative stress and inflammatory processes, as we discuss in this paper.

  19. Ages and Ages: The Multiplication of Children's "Ages" in Early Twentieth-Century Child Psychology

    Science.gov (United States)

    Beauvais, Clementine

    2016-01-01

    This paper explores the trend, between 1905 and the late 1920s in UK and US child psychology, of "discovering," labelling and calculating different "ages" in children. Those new "ages"--from mental to emotional, social, anatomical ages, and more--were understood as either replacing, or meaningfully related to,…

  20. Wisdom comes with age?

    CERN Multimedia

    2009-01-01

    ‘A relativistic generalization of the Navier-Stokes equations to quark-gluon plasmas’ – the work of a CERN physicist perhaps? No, actually it is the title of a high school student’s project! Thirteen of the world’s brightest young scientific minds were recently treated to a tour of CERN. The Bulletin finds out more. The Intel ISEF students during their visit to CERN.Thirteen science wunderkinds came to CERN for a three-day visit on 29 June. The high school students, aged between 16 and 18, were all winners of this year’s Intel International Science and Engineering Fair (Intel ISEF), the world’s largest pre-college science competition. As part of their prize they won a visit to CERN organized by the CERN openlab collaboration (see box). "The whole trip has been incredible, and this is my first time in Europe as well so that makes it even more exciting," said Ryan Alexander, just 16 years old, who won in the Energy and Tr...

  1. Aging and operation results

    International Nuclear Information System (INIS)

    The correlation between the different accelerated aging methods and operation reality has to be done with solid and representative elements in matter of tests as well as in operating experience. In 1990 in France, the first unit will be 13 years operating, there will be 34 units of 900 MW PWR and 18 units of 1300 MW PWR in operation. The total of experience will be equivalent to 400 reactor-years. Only computerised means permit to collect all corresponding events, to manage them and to draw a lot of conclusions. One describes these computerised applications explaining the different events collected, data input and interrogating possibilities. The first application, called ''events file'', records all important events in nuclear plants. For each of these events, an event reporting format is set up as soon as first informations are known and then is put into the file. An updating is performed when the event is better known and analyzed. Interrogating programs allow no specialist to access easily to this data bank. So it is possible to collect events of the same nature, of the same equipments or of the same systems. The second application called S.R.D.F. (fiability data bank system) collects all maintenance operations on certain mechanical and electrical equipment. These two computerized applications complete on another in the way they allow to do fiability and availability studies for some equipments or for some elements of a nuclear plant

  2. Ageing and water homeostasis

    Science.gov (United States)

    Robertson, David; Jordan, Jens; Jacob, Giris; Ketch, Terry; Shannon, John R.; Biaggioni, Italo

    2002-01-01

    This review outlines current knowledge concerning fluid intake and volume homeostasis in ageing. The physiology of vasopressin is summarized. Studies have been carried out to determine orthostatic changes in plasma volume and to assess the effect of water ingestion in normal subjects, elderly subjects, and patients with dysautonomias. About 14% of plasma volume shifts out of the vasculature within 30 minutes of upright posture. Oral ingestion of water raises blood pressure in individuals with impaired autonomic reflexes and is an important source of noise in blood pressure trials in the elderly. On the average, oral ingestion of 16 ounces (473ml) of water raises blood pressure 11 mmHg in elderly normal subjects. In patients with autonomic impairment, such as multiple system atrophy, strikingly exaggerated pressor effects of water have been seen with blood pressure elevations greater than 75 mmHg not at all uncommon. Ingestion of water is a major determinant of blood pressure in the elderly population. Volume homeostasis is importantly affected by posture and large changes in plasma volume may occur within 30 minutes when upright posture is assumed.

  3. Active ageing and the unmaking of old age

    DEFF Research Database (Denmark)

    Lassen, Aske Juul

    -private innovation partnership (PPIP) that developed technologies catering to the active late life. A thorough analysis of active ageing entails studying what precisely active ageing tries to solve. I approach ageing as a matter of concern, a term proposed by Bruno Latour to describe how myriad practices and...... analysis of active ageing has changed throughout the project, I demonstrate how method, theory, and analysis intersect. Part 1 ends with my proposal of fibres as a tool to study matters of concern. In part 2, I dedicate a chapter to each of the three entangled formations. In chapter 5, I examine how...... article A, I describe how I participated in the innovation process of new technologies that cater to active ageing, and show how a specific kind of late life is assumed in such innovation processes. In article B, I portray active ageing as multiple knowledge-driven policy formats, which intend to unmake...

  4. PGC-1α in aging and anti-aging interventions

    OpenAIRE

    Anderson, Rozalyn; Prolla, Tomas

    2009-01-01

    Deregulation of mitochondrial function is a common feature in multiple aspects of aging. In addition to playing a role in aging-associated disease, decline in mitochondrial energy metabolism is likely to be important in the development of metabolic disease. Furthermore, altered mitochondrial function is a conserved feature in caloric restriction – a dietary intervention that delays aging in diverse species. The transcriptional co-activator PGC-1α is a critical regulator of mitochondrial energ...

  5. "Is old age stigma? Ageing identity in Lithuania"

    OpenAIRE

    Rapolienė, Grazina

    2012-01-01

    While population ageing is attracting ever more attention of international scientific community and social policy, its cultural and communicative aspects remain underinvestigated. The goal of the dissertation is to investigate the old age (ageing) identity in Lithuania, applying the sociological concept of stigma. In the pursuit of this goal, the research areas of stigma and ageism are connected, highlighting their common denominator - discrimination. The following questions are raised: wheth...

  6. Transgender, aging and old age - Do transgender people get old?

    OpenAIRE

    Pedro Paulo Sammarco Antunes; Elisabeth Frohlich Mercadante

    2013-01-01

    This study is aimed to understand transgender aging context in Brazil. Normal and abnormal were especially created by biological sciences. For being considered deviants, transgender people are not seen as human beings. They end up living in violent environments. Their life expectancy is low. Many of them do not believe to reach old age. They face a lot of prejudice and death threat. Those who get to what we call old age are considered survivals. This investigation was able to show satisfactor...

  7. Ageing Populations in Post-Industrial Democracies

    DEFF Research Database (Denmark)

    Vanhuysse, Pieter; Goerres, Achim

    examines changing electoral policy demands due to demographic ageing, and features analysis of USA, UK, Japan, Germany, Italy and all major EU countries.As the first sustained political science analysis of population ageing, this monograph examines both sides of the debate. It examines the actions...... productive as they are politically contentious.' - Martin Kohli, Professor of Sociology, European University Institute Florence 'The process of population ageing has been compared to a seismic shift which has profound consequences on all aspects of our societies but is too slow to make headlines or matter...... by the age of the electorate (particularly pension reform and generosity), while it seems that the interests of the elderly are not necessarily privileged during the design of labour market reforms.’ - Intergenerational Justice Review‘Pieter Vanhuysse and Achim Goerres wish to shed light on the consequences...

  8. Aging and functional brain networks

    Energy Technology Data Exchange (ETDEWEB)

    Tomasi D.; Tomasi, D.; Volkow, N.D.

    2011-07-11

    Aging is associated with changes in human brain anatomy and function and cognitive decline. Recent studies suggest the aging decline of major functional connectivity hubs in the 'default-mode' network (DMN). Aging effects on other networks, however, are largely unknown. We hypothesized that aging would be associated with a decline of short- and long-range functional connectivity density (FCD) hubs in the DMN. To test this hypothesis, we evaluated resting-state data sets corresponding to 913 healthy subjects from a public magnetic resonance imaging database using functional connectivity density mapping (FCDM), a voxelwise and data-driven approach, together with parallel computing. Aging was associated with pronounced long-range FCD decreases in DMN and dorsal attention network (DAN) and with increases in somatosensory and subcortical networks. Aging effects in these networks were stronger for long-range than for short-range FCD and were also detected at the level of the main functional hubs. Females had higher short- and long-range FCD in DMN and lower FCD in the somatosensory network than males, but the gender by age interaction effects were not significant for any of the networks or hubs. These findings suggest that long-range connections may be more vulnerable to aging effects than short-range connections and that, in addition to the DMN, the DAN is also sensitive to aging effects, which could underlie the deterioration of attention processes that occurs with aging.

  9. Evolution of ageing since Darwin

    Indian Academy of Sciences (India)

    Michael R. Rose; Molly K. Burke; Parvin Shahrestani; Laurence D. Mueller

    2008-12-01

    In the late 19th century, the evolutionary approach to the problem of ageing was initiated by August Weismann, who argued that natural selection was more important for ageing than any physiological mechanism. In the mid-twentieth century, J. B. S. Haldane, P. B. Medawar and G. C. Williams informally argued that the force of natural selection falls with adult age. In 1966, W. D. Hamilton published formal equations that showed mathematically that two ‘forces of natural selection’ do indeed decline with age, though his analysis was not genetically explicit. Brian Charlesworth then developed the required mathematical population genetics for the evolution of ageing in the 1970’s. In the 1980’s, experiments using Drosophila showed that the rate of ageing evolves as predicted by Hamilton’s ‘forces of natural selection’. The discovery of the cessation of ageing late in life in the 1990’s was followed by its explanation in terms of evolutionary theory based on Hamilton’s forces. Recently, it has been shown that the cessation of ageing can also be manipulated experimentally using Hamilton’s ‘forces of natural selection’. Despite the success of evolutionary research on ageing, mainstream gerontological research has largely ignored both this work and the opportunity that it provides for effective intervention in ageing.

  10. Reliability methods and ageing management

    International Nuclear Information System (INIS)

    The aim of nuclear power plant ageing management is to maintain an adequate safety level through the planned and possibly extended lifetime of a plant. The technical definition of ageing is the following : ageing is the continuous time-dependent degradation of materials due to normal service conditions, which include normal operation and transient conditions (IAEA 1990). A logical concern for extending the life of nuclear power plants is whether plants age in such a way as to be significantly less safe as they get older. Generally, the overall reactor plant performance is used as a way of measuring the effect of plant aging. The performance indicators are : - number of scrams while critical; - number of selected safety system actuations; - number of significant operating events; - number of safety system failures; - forced outage rates; - number of equipment-forced outages; - collective radiation exposure per plant. Reliability methods are essential in the integration of component-specific ageing and degradation studies with the plant or system level analyses. Reliability based approaches together with the use of plant operating experience have an important role in all stages of ageing analyses. The phases of ageing analyses are (generally speaking): the identification of critical components, identification and evaluation of ageing effects and development of mitigation methods. The probabilistic safety analysis, PSA, is an efficient system analysis method, which is used to assess risk of operation of nuclear power plants. This paper promotes the use of reliability methods and a system analysis approach in nuclear power plant ageing management. (authors)

  11. THE LINK BETWEEN ACTIVE AGING AND RETIREMENT AGE

    OpenAIRE

    Mihai Robert, PAŞNICU

    2014-01-01

    The paper aims to shed light on the policies and consequences of the current retirement age in Romania. The retirement age has been repeatedly incremented in Romania in the last couple of years in order to try to compensate for the fact that the country has a low general employment rate, only 30% of the population, while having 20% of the total population aged 65+. By using an econometric model we will first prove the existence of an optimal retirement age that might vary for each and every o...

  12. Active Aging Promotion: Results from the Vital Aging Program

    Directory of Open Access Journals (Sweden)

    Mariagiovanna Caprara

    2013-01-01

    Full Text Available Active aging is one of the terms in the semantic network of aging well, together with others such as successful, productive, competent aging. All allude to the new paradigm in gerontology, whereby aging is considered from a positive perspective. Most authors in the field agree active aging is a multidimensional concept, embracing health, physical and cognitive fitness, positive affect and control, social relationships and engagement. This paper describes Vital Aging, an individual active aging promotion program implemented through three modalities: Life, Multimedia, and e-Learning. The program was developed on the basis of extensive evidence about individual determinants of active aging. The different versions of Vital Aging are described, and four evaluation studies (both formative and summative are reported. Formative evaluation reflected participants’ satisfaction and expected changes; summative evaluations yielded some quite encouraging results using quasi-experimental designs: those who took part in the programs increased their physical exercise, significantly improved their diet, reported better memory, had better emotional balance, and enjoyed more cultural, intellectual, affective, and social activities than they did before the course, thus increasing their social relationships. These results are discussed in the context of the common literature within the field and, also, taking into account the limitations of the evaluations accomplished.

  13. Electrical Aging Phenomena of Power Cables Aged by Switching Impulses

    Institute of Scientific and Technical Information of China (English)

    L.Cao; A.Zanwar; S.Grzybowski

    2013-01-01

    Due to the insufficient information regarding the aging phenomenon of cables caused by switching impulses,we aged 15 kV XLPE and EPR cable samples by 10000 switching impulses in experiments and tested them.Plus in order to compare the aging phenomenon under multi-stress conditions,additional EPR cable samples were aged by rated AC voltage and current with switching impulses superimposed.We used measurements of partial discharge parameters to monitor the cables' conditions during their aging process,and the AC breakdown voltages measurement to evaluate the cables after aging.Moreover,the Fourier transform infrared (FTIR) spectroscopy measurements revealed the changes of insulation materials after aging.The measurement results confirm that the accelerated aging of cable samples had taken place.The impacts of each individual aging factor are shown through the selected measurements and comparison.The study also helps to assess the reliability of the XLPE and EPR cables under similar condition while serving in power systems.

  14. Mars Ice Age, Simulated

    Science.gov (United States)

    2003-01-01

    December 17, 2003This simulated view shows Mars as it might have appeared during the height of a possible ice age in geologically recent time.Of all Solar System planets, Mars has the climate most like that of Earth. Both are sensitive to small changes in orbit and tilt. During a period about 2.1 million to 400,000 years ago, increased tilt of Mars' rotational axis caused increased solar heating at the poles. A new study using observations from NASA's Mars Global Surveyor and Mars Odyssey orbiters concludes that this polar warming caused mobilization of water vapor and dust into the atmosphere, and buildup of a surface deposit of ice and dust down to about 30 degrees latitude in both hemispheres. That is the equivalent of the southern Unites States or Saudi Arabia on Earth. Mars has been in an interglacial period characterized by less axial tilt for about the last 300,000 years. The ice-rich surface deposit has been degrading in the latitude zone of 30 degrees to 60 degrees as water-ice returns to the poles.In this illustration prepared for the December 18, 2003, cover of the journal Nature, the simulated surface deposit is superposed on a topography map based on altitude measurements by Global Surveyor and images from NASA's Viking orbiters of the 1970s.Mars Global Surveyor and Mars Odyssey are managed by NASA's Jet Propulsion Laboratory, a division of the California Institute of Technology, Pasadena, for the NASA Office of Space Science, Washington.

  15. Estimating The Age-Productivity Profile Using Lifetime Earnings

    OpenAIRE

    Kotlikoff, Laurence J.

    1988-01-01

    Understanding how productivity varies with age is important for a variety of reasons. A decline in productivity with age implies that aging societies must increasingly depend on the labor supply of the young and middle age. It also means that policies designed to keep the elderly in the work force, while potentially good for the elderly, may decrease overall productivity. A third implication is that, absent government intervention, employers may not be willing to hire the elderly for the same...

  16. An International Perspective on Aging and Cognitive Decline

    OpenAIRE

    Weber, Daniela

    2015-01-01

    Worldwide populations are growing older. Thus, many countries fear economic and societal burden, but population aging can also be seen as an opportunity for a society. Which view prevails is very much dependent on the chosen measures of aging that are so far mainly based on chronological age. In the first part of this thesis measures of population aging are analyzed and new measures are proposed. The novel cognition adjusted dependency ratio (CADR) is introduced as an alternative to the o...

  17. Expatriate job performance in Greater China: Does age matter?

    DEFF Research Database (Denmark)

    Selmer, Jan; Lauring, Jakob; Feng, Yunxia

    As opposed to the predominant belief in the West, in Chinese dominated societies there may be a positive relationship between age and perceived possession of high quality personal resources and older people are traditionally treated with respect. This attitude towards old age may carry over to...... association with the age of the expatriates. This finding provides partial affirmative support to the presumption that the age of business expatriates matters in a Chinese cultural context. Implications of this result are discussed in detail....

  18. Imaging in the Age of Precision Medicine: Summary of the Proceedings of the 10th Biannual Symposium of the International Society for Strategic Studies in Radiology.

    Science.gov (United States)

    Herold, Christian J; Lewin, Jonathan S; Wibmer, Andreas G; Thrall, James H; Krestin, Gabriel P; Dixon, Adrian K; Schoenberg, Stefan O; Geckle, Rena J; Muellner, Ada; Hricak, Hedvig

    2016-04-01

    During the past decade, with its breakthroughs in systems biology, precision medicine (PM) has emerged as a novel health-care paradigm. Challenging reductionism and broad-based approaches in medicine, PM is an approach for disease treatment and prevention that takes into account individual variability in genes, environment, and lifestyle. It involves integrating information from multiple sources in a holistic manner to achieve a definitive diagnosis, focused treatment, and adequate response assessment. Biomedical imaging and imaging-guided interventions, which provide multiparametric morphologic and functional information and enable focused, minimally invasive treatments, are key elements in the infrastructure needed for PM. The emerging discipline of radiogenomics, which links genotypic information to phenotypic disease manifestations at imaging, should also greatly contribute to patient-tailored care. Because of the growing volume and complexity of imaging data, decision-support algorithms will be required to help physicians apply the most essential patient data for optimal management. These innovations will challenge traditional concepts of health care and business models. Reimbursement policies and quality assurance measures will have to be reconsidered and adapted. In their 10th biannual symposium, which was held in August 2013, the members of the International Society for Strategic Studies in Radiology discussed the opportunities and challenges arising for the imaging community with the transition to PM. This article summarizes the discussions and central messages of the symposium. (©) RSNA, 2015. PMID:26465058

  19. Successful aging and the epidemiology of HIV

    Directory of Open Access Journals (Sweden)

    Vance DE

    2011-06-01

    Full Text Available David E Vance1, Teena McGuinness1, Karen Musgrove3, Nancy Ann Orel4, Pariya L Fazeli21School of Nursing, 2Department of Psychology and Center for Research in Applied Gerontology, University of Alabama at Birmingham, 3Birmingham AIDS Outreach, Birmingham, AL, USA; 4Gerontology Program, Bowling Green State University, Bowling Green, OH, USAAbstract: By 2015, it is estimated that nearly half of those living with HIV in the US will be 50 years of age and older. This dramatic change in the demographics of this clinical population represents unique challenges for patients, health care providers, and society-at-large. Fortunately, because of highly active antiretroviral therapy (HAART and healthy lifestyle choices, it is now possible for many infected with HIV to age successfully with this disease; however, this depends upon one’s definition of successful aging. It is proposed that successful aging is composed of eight factors: length of life, biological health, cognitive efficiency, mental health, social competence, productivity, personal control, and life satisfaction. Unfortunately, HIV and medication side effects can compromise these factors, thus diminishing one’s capacity to age successfully with this disease. This article explores how HIV, medication side effects from HAART, and lifestyle choices can compromise the factors necessary to age successfully. Implications for practice and research are posited.Keywords: HIV, AIDS, successful aging, spirituality, depression, hardiness

  20. Age estimation in the living

    DEFF Research Database (Denmark)

    Larsen, Sara Tangmose; Thevissen, Patrick; Lynnerup, Niels;

    2015-01-01

    A radiographic assessment of third molar development is essential for differentiating between juveniles and adolescents in forensic age estimations. As the developmental stages of third molars are highly correlated, age estimates based on a combination of a full set of third molar scores are...... statistically complicated. Transition analysis (TA) is a statistical method developed for estimating age at death in skeletons, which combines several correlated developmental traits into one age estimate including a 95% prediction interval. The aim of this study was to evaluate the performance of TA in the...... living on a full set of third molar scores. A cross sectional sample of 854 panoramic radiographs, homogenously distributed by sex and age (15.0-24.0 years), were randomly split in two; a reference sample for obtaining age estimates including a 95% prediction interval according to TA; and a validation...

  1. Changing Age and Household Patterns

    DEFF Research Database (Denmark)

    Højbjerg Jacobsen, Rasmus; Hougaard Jensen, Svend E.

    2014-01-01

    , lone parents and cohabiting couples. Focusing on components of welfare services with noticeable differences in unit costs across age and household status, we find that changes in age structures have improved public finances by 1.6% of GDP whereas changing household structures have worsened public......This paper studies the effects on tax revenues and welfare expenditures in Denmark caused by changes in age and household structures over the years 1982-2007. During that period, there has been a minor fall in the old-age dependency ratio, and a major increase in the number of people living alone...... finances by almost 1% of GDP on the yearly budget. While the net fiscal effect of changing household structures is minor, the gross effects are substantial. In a future characterized by population ageing, public finances may be adversely affected by changes in both age and household structures, thus...

  2. Leisure in old age – disciplinary practices surrounding the discourse of active ageing

    Directory of Open Access Journals (Sweden)

    Jaroslava Hasmanová Marhánkova

    2011-10-01

    Full Text Available In the 1990s, the World Health Organization adopted the term ‘‘active ageing’’, which currently represents a key vision of old age in Western societies facing the situation of demographic ageing. The meaning of the idea of active ageing is based on the concept of individuals actively and systematically influencing the conditions of their ageing through selfresponsibility and self-care. The aim of this article is to map how the idea of active ageing is constructed and the implications it presents with regard to the way in which seniors relate to their experience of old age. It concentrates on a pecific segment of senior-oriented social services (centres for seniors that offer leisure time activities and educational courses that represent an institutional context for the manifestation of the discourse of active ageing. A three-year ethnographic study was conducted in two such centres in the Czech Republic. The article focuses on various strategies for the disciplining of the ageing body. It points out that these disciplinary practices are an integral part of the daily running of the centres and that the seniors who intensively engage in them have internalised the idea of an active lifestyle as the most desirable lifestyle in old age. Active ageing was constructed by them as a project that must be worked on. Through the ‘‘technologies of self’’ embedded in the imperative of the necessity to move or do something, they participate in the production of the discourse of active ageing as a form of discipline of the body. At the same time, the article outlines how the idea of active ageing as the ‘‘correct’’ form of ageing influences the self-conception of these seniors and their attitudes towards ageing and their peers.

  3. [Environmentally induced (extrinsic) skin aging].

    Science.gov (United States)

    Krutmann, J; Schikowski, T; Hüls, A; Vierkötter, A; Grether-Beck, S

    2016-02-01

    Chronic exposure to ultraviolet light, particularly as a component of natural sunlight, is a major cause of environmentally induced aging of the skin. In addition, other environmental factors for premature skin aging include longer wavelength radiation in the visible light region and in particular in the shortwave infrared radiation region. Furthermore, particulate and gaseous components of air pollution significantly contribute to the aging process. PMID:26769311

  4. Control of NPP aging processes

    International Nuclear Information System (INIS)

    The concept of the control program on the NPP aging processes is considered. The methodological algorithms for the working programs plotting and realization, intended for accomplishing the measures for mitigating the aging mechanisms and factors, effecting the NPP safety, are presented. The efficiency of the equipment for the aging processes control and power units systems, aimed at the control of the NPP service life, is analyzed

  5. Social Support in Normal Aging

    OpenAIRE

    Matthews, Anne Martin

    1984-01-01

    The role of social support in helping elderly people deal with stressful life events is quite complex. This complexity exists because it is difficult to define exactly what social support is, and because the experiences of `normal' aging vary. This article uses the example of adaptation to widowhood to examine the relationship between normal aging and sources, types, and patterns of social support. These factors influence the extent to which support lessens the impact of age-related stressful...

  6. Mobility decline in old age

    DEFF Research Database (Denmark)

    Rantakokko, Merja; Mänty, Minna Regina; Rantanen, Taina

    2013-01-01

    Mobility is important for community independence. With increasing age, underlying pathologies, genetic vulnerabilities, physiological and sensory impairments, and environmental barriers increase the risk for mobility decline. Understanding how mobility declines is paramount to finding ways to pro...... promote mobility in old age.......Mobility is important for community independence. With increasing age, underlying pathologies, genetic vulnerabilities, physiological and sensory impairments, and environmental barriers increase the risk for mobility decline. Understanding how mobility declines is paramount to finding ways to...

  7. Postponing the legal retirement age

    OpenAIRE

    Lacomba, Juan Antonio; Lagos, Francisco Miguel

    2010-01-01

    This paper analyzes the reform of the pensionable age as an answer to the future financing problems of public pension systems. We use a two-staged model where, first, the government decides the redistribution level of the pension system and, secondly, individuals face a voting process on the legal retirement age. The results suggest that governments attempting to postpone the legal retirement age should increase the degree of intra-generational redistribution of the pension system in order to...

  8. Skin aging and oxidative stress

    OpenAIRE

    Sayeeda Ahsanuddin; Minh Lam; Baron, Elma D.

    2016-01-01

    Skin aging occurs through two main pathways, intrinsic and extrinsic. These pathways have significant interaction in contributing to the aging phenotype, which includes skin laxity, wrinkling, pigmentation irregularities, and the appearance of neoplastic skin lesions. Here, we review the critical role that oxidative stress plays in skin aging, including its effects on signaling pathways involved in skin matrix formation and degradation, proteasome activity, as well as DNA structure. Furthermo...

  9. Nutrients for the aging eye

    OpenAIRE

    Rasmussen HM; Johnson EJ

    2013-01-01

    Helen M Rasmussen,1 Elizabeth J Johnson2 1Educational Studies, Lesley University, Cambridge, MA, USA; 2Carotenoid and Health Laboratory, Jean Mayer US Department of Agriculture Human Nutrition Research Center on Aging at Tufts University, Boston, MA, USA Abstract: The incidence of age-related eye diseases is expected to rise with the aging of the population. Oxidation and inflammation are implicated in the etiology of these diseases. There is evidence that dietary antioxidants and anti-infla...

  10. Aging and consumer decision making

    OpenAIRE

    Carpenter, Stephanie M.; Yoon, Carolyn

    2011-01-01

    Research on consumer decision making and aging is especially important for fostering a better understanding of ways to maintain consumer satisfaction and high decision quality across the life span. We provide a review of extant research on the effects of normal aging on cognition and decision processes and how these age-related processes are influenced by task environment, meaningfulness of the task, and consumer expertise. We consider how research centered on these topics generates insights ...

  11. Molecular Mechanisms of Cardiovascular Aging

    OpenAIRE

    Anna Meiliana; Andi Wijaya

    2013-01-01

    BACKGROUND: The average lifespan of humans is increasing, and with it the percentage of people entering the 65 and older age group is growing rapidly and will continue to do so in the next 20 years. Within this age group, cardiovascular disease will remain the leading cause of death, and the cost associated with treatment will continue to increase. Aging is an inevitable part of life and unfortunately poses the largest risk factor for cardiovascular disease. CONTENT: We provide an overview of...

  12. Ageing of ships, LPG tankers

    OpenAIRE

    Ask, Martin

    2015-01-01

    During the last decades there have been several major ship accidents, and it is believed that old ships are more unsafe than newer ships. To get a better understanding of this phenomenon the thesis is investigating different issues with ship ageing. This thesis consists of a general description of the most important ageing issues, and the condition of sea water ballast tanks is identified as one of the most critical issue regarded to ageing on LPG-tankers. This investigation consists of...

  13. School Starting Age and Crime

    DEFF Research Database (Denmark)

    Landersø, Rasmus; Nielsen, Helena Skyt; Simonsen, Marianne

    This paper investigates the effects of school starting age on crime while relying on variation in school starting age induced by administrative rules; we exploit that Danish children typically start first grade in the calendar year they turn seven, which gives rise to a discontinuity in children’s...... school starting age. Analyses are carried out using register-based Danish data. We find that higher age at school start lowers the propensity to commit crime, but that this reduction is caused by incapacitation while human capital accumulation is unaffected. Importantly, we also find that the individuals...

  14. Theoretical approach to biological aging

    CERN Document Server

    D'Almeida, R M C; Penna, T J P

    1997-01-01

    We present a model for biological aging that considers the number of individuals whose (inherited) genetic charge determines the maximum age for death: each individual may die before that age due to some external factor, but never after that limit. The genetic charge of the offspring is inherited from the parent with some mutations, described by a transition matrix. The model can describe different strategies of reproduction and it is exactly soluble. We applied our method to the bit-string model for aging and the results are in perfect agreement with numerical simulations.

  15. Relationships between Housing and Healthy Aging in Very Old Age

    Science.gov (United States)

    Oswald, Frank; Wahl, Hans-Werner; Schilling, Oliver; Nygren, Carita; Fange, Agneta; Sixsmith, Andrew; Sixsmith, Judith; Szeman, Zsuzsa; Tomsone, Signe; Iwarsson, Susanne

    2007-01-01

    Purpose: The aim of this work is to examine the relationship between aspects of objective and perceived housing and aspects of healthy aging, defined as independence in daily activities and subjective well-being. Furthermore, this research examined the comparability of relationships between housing and healthy aging in the five European countries.…

  16. THE AMERICAN DARK AGES

    OpenAIRE

    Hayırlı, Onur; İşler, Dilek

    2015-01-01

    This article historically will review some cases for lynch culture which is again blacks in America. And will examine the term ‘Afro-American’. Cases like ‘Michael Brown’, ‘Eric Garner’ and ‘Antonio Martin’ are proof of violence is still going on again black society.Lynching is a part of America’s dark sides. Behind lynching, it lays a brutal history of domestic violence. For years, maybe for centuries, American people have lynched Black people because of various accusations. These lynching w...

  17. The aging mouth: differentiating normal aging from disease.

    Science.gov (United States)

    Lamster, Ira B; Asadourian, Lynda; Del Carmen, Tessa; Friedman, Paula K

    2016-10-01

    Aging is the physiologic change that occurs over time. In humans, this change occurs at different rates and are related to lifestyle, environment and genetics. It can be challenging to differentiate normal aging from disease. In the oral cavity, with increasing age the teeth demonstrate wearing of the enamel, chipping and fracture lines, and a darker color. The pulp chamber and canals are reduced in size as a result of the deposition of secondary dentin. Coronal or root caries, however, represent disease. A limited amount of periodontal attachment loss occurs in association with aging, usually manifesting as recession on the buccal surface of teeth. Severe periodontitis occurs in 10.5-12% of the population, with the peak incidence being observed at 35-40 years of age. Changes to the mucosal tissue that occur with age include reduced wound-healing capacity. However, environmental factors, such as smoking, dramatically increase the risk of mucosal pathology. Reduced salivary gland function is often seen in association with medication usage, as well as with disorders such as diabetes mellitus. Both medication use and chronic disorders are more common in older adults. Masticatory function is of particular importance for older adults. Maintenance of a nutritionally complete diet is important for avoiding sarcopenia and the frailty syndrome. Successful oral aging is associated with adequate function and comfort. A reduced, but functional, dentition of 20 teeth in occlusion has been proposed as a measure of successful oral aging. Healthy oral aging is important to healthy aging from both biological and social perspectives. PMID:27501493

  18. Design Evolution Study - Aging Options

    International Nuclear Information System (INIS)

    The purpose of this study is to identify options and issues for aging commercial spent nuclear fuel received for disposal at the Yucca Mountain Mined Geologic Repository. Some early shipments of commercial spent nuclear fuel to the repository may be received with high-heat-output (younger) fuel assemblies that will need to be managed to meet thermal goals for emplacement. The capability to age as much as 40,000 metric tons of heavy metal of commercial spent nuclear he1 would provide more flexibility in the design to manage this younger fuel and to decouple waste receipt and waste emplacement. The following potential aging location options are evaluated: (1) Surface aging at four locations near the North Portal; (2) Subsurface aging in the permanent emplacement drifts; and (3) Subsurface aging in a new subsurface area. The following aging container options are evaluated: (1) Complete Waste Package; (2) Stainless Steel inner liner of the waste package; (3) Dual Purpose Canisters; (4) Multi-Purpose Canisters; and (5) New disposable canister for uncanistered commercial spent nuclear fuel. Each option is compared to a ''Base Case,'' which is the expected normal waste packaging process without aging. A Value Engineering approach is used to score each option against nine technical criteria and rank the options. Open issues with each of the options and suggested future actions are also presented. Costs for aging containers and aging locations are evaluated separately. Capital costs are developed for direct costs and distributable field costs. To the extent practical, unit costs are presented. Indirect costs, operating costs, and total system life cycle costs will be evaluated outside of this study. Three recommendations for aging commercial spent nuclear fuel--subsurface, surface, and combined surface and subsurface are presented for further review in the overall design re-evaluation effort. Options that were evaluated but not recommended are: subsurface aging in a new

  19. Design Evolution Study - Aging Options

    Energy Technology Data Exchange (ETDEWEB)

    P. McDaniel

    2002-04-05

    The purpose of this study is to identify options and issues for aging commercial spent nuclear fuel received for disposal at the Yucca Mountain Mined Geologic Repository. Some early shipments of commercial spent nuclear fuel to the repository may be received with high-heat-output (younger) fuel assemblies that will need to be managed to meet thermal goals for emplacement. The capability to age as much as 40,000 metric tons of heavy metal of commercial spent nuclear he1 would provide more flexibility in the design to manage this younger fuel and to decouple waste receipt and waste emplacement. The following potential aging location options are evaluated: (1) Surface aging at four locations near the North Portal; (2) Subsurface aging in the permanent emplacement drifts; and (3) Subsurface aging in a new subsurface area. The following aging container options are evaluated: (1) Complete Waste Package; (2) Stainless Steel inner liner of the waste package; (3) Dual Purpose Canisters; (4) Multi-Purpose Canisters; and (5) New disposable canister for uncanistered commercial spent nuclear fuel. Each option is compared to a ''Base Case,'' which is the expected normal waste packaging process without aging. A Value Engineering approach is used to score each option against nine technical criteria and rank the options. Open issues with each of the options and suggested future actions are also presented. Costs for aging containers and aging locations are evaluated separately. Capital costs are developed for direct costs and distributable field costs. To the extent practical, unit costs are presented. Indirect costs, operating costs, and total system life cycle costs will be evaluated outside of this study. Three recommendations for aging commercial spent nuclear fuel--subsurface, surface, and combined surface and subsurface are presented for further review in the overall design re-evaluation effort. Options that were evaluated but not recommended are

  20. AGES in brain ageing: AGE-inhibitors as neuroprotective and anti-dementia drugs?

    Science.gov (United States)

    Dukic-Stefanovic, S; Schinzel, R; Riederer, P; Münch, G

    2001-01-01

    In Alzheimer's disease, age-related cellular changes such as compromised energy production and increased radical formation are worsened by the presence of AGEs as additional, AD specific stress factors. Intracellular AGEs (most likely derived from methylglyoxal) crosslink cytoskeletal proteins and render them insoluble. These aggregates inhibit cellular functions including transport processes and contribute to neuronal dysfunction and death. Extracellular AGEs, which accumulate in ageing tissue (but most prominently on long-lived protein deposits like the senile plaques) exert chronic oxidative stress on neurons. In addition, they activate glial cells to produce free radicals (superoxide and NO) and neurotoxic cytokines such as TNF-alpha. Drugs, which inhibit the formation of AGEs by specific chemical mechanisms (AGE-inhibitors), including aminoguanidine, carnosine, tenilsetam, OPB-9195 and pyridoxamine, attenuate the development of (AGE-mediated) diabetic complications. Assuming that 'carbonyl stress' contributes significantly to the progression of Alzheimer's disease, AGE-inhibitors might also become interesting novel therapeutic drugs for treatment of AD. PMID:11708614

  1. Chinese Middle-Aged Confusion

    Institute of Scientific and Technical Information of China (English)

    CHENXINXIN

    2003-01-01

    THE middle-aged generation,those of the age 40 to 55, is special in China. Born in the 1950s and early 1960s, they grew up in the most difficult and chaotic periods of recent Chinese history, having experienced and suffered the Great Leap Forward at the end of the fifties and the “cultural revolution” ( 1966-1976).

  2. Age and Clinical Dengue Illness

    OpenAIRE

    Egger, Joseph R.; Paul G Coleman

    2007-01-01

    The relationship between age and risk for classic dengue fever has never been quantified. We use data from clinical patients to show that the relative risk of having classical disease after primary dengue virus infection increases with age. This relationship has implications for strategies aimed at controlling dengue fever.

  3. ESTIMATION OF AGE TRANSITION PROBABILITIES.

    Science.gov (United States)

    ZINTER, JUDITH R.

    THIS NOTE DESCRIBES THE PROCEDURES USED IN DETERMINING DYNAMOD II AGE TRANSITION MATRICES. A SEPARATE MATRIX FOR EACH SEX-RACE GROUP IS DEVELOPED. THESE MATRICES WILL BE USED AS AN AID IN ESTIMATING THE TRANSITION PROBABILITIES IN THE LARGER DYNAMOD II MATRIX RELATING AGE TO OCCUPATIONAL CATEGORIES. THREE STEPS WERE USED IN THE PROCEDURE--(1)…

  4. Leading in a Technological Age

    Science.gov (United States)

    Yadgir, Sheri A.

    2011-01-01

    Technology is advancing more rapidly than at any time in history since the beginning of the Industrial Revolution. In fact, experts say that the world is leaving the Industrial Age of the 20th century and entering an Information Age that will lead into the future. These advances mean that important changes are being made in all areas of life--and…

  5. Mitochondrial Metabolism in Aging Heart.

    Science.gov (United States)

    Lesnefsky, Edward J; Chen, Qun; Hoppel, Charles L

    2016-05-13

    Altered mitochondrial metabolism is the underlying basis for the increased sensitivity in the aged heart to stress. The aged heart exhibits impaired metabolic flexibility, with a decreased capacity to oxidize fatty acids and enhanced dependence on glucose metabolism. Aging impairs mitochondrial oxidative phosphorylation, with a greater role played by the mitochondria located between the myofibrils, the interfibrillar mitochondria. With aging, there is a decrease in activity of complexes III and IV, which account for the decrease in respiration. Furthermore, aging decreases mitochondrial content among the myofibrils. The end result is that in the interfibrillar area, there is ≈50% decrease in mitochondrial function, affecting all substrates. The defective mitochondria persist in the aged heart, leading to enhanced oxidant production and oxidative injury and the activation of oxidant signaling for cell death. Aging defects in mitochondria represent new therapeutic targets, whether by manipulation of the mitochondrial proteome, modulation of electron transport, activation of biogenesis or mitophagy, or the regulation of mitochondrial fission and fusion. These mechanisms provide new ways to attenuate cardiac disease in elders by preemptive treatment of age-related defects, in contrast to the treatment of disease-induced dysfunction. PMID:27174952

  6. Telomerase and the aging process

    OpenAIRE

    Hornsby, Peter J.

    2007-01-01

    The level of telomerase activity is important in determining telomere length in aging cells and tissues. Here evidence on the importance of telomerase activity is reviewed with respect to aging rates of mammalian species and the health and life span of individuals within a species. The significance of telomerase reactivation for both cancer development and for immortalizing cells for therapeutic processes is assessed.

  7. Age distribution of anginose mononucleosis.

    OpenAIRE

    Spirer, Z; Holtzman, M; Melamed, I; Shalit, I

    1987-01-01

    The age distribution of anginose infectious mononucleosis in children was analysed retrospectively for the years 1966-85. During that period the disease became significantly more common in children of a young age and less common in older children. This shift could not be attributed either to socioeconomic conditions or to the diagnostic methods used.

  8. The Several Ages of Learning

    Science.gov (United States)

    Bailey, Stephen

    1976-01-01

    Examines the various stages of human development (as outlined by Erik Erikson and others) with their psychological stresses of recurring crises of identity and expectation and explores some of the implications for education's best serving human needs. Focuses on early childhood, late adolescence, middle age, and old age. (JT)

  9. Population Ageing and Technological Change

    OpenAIRE

    Wright, Robert E.; Jouko Kinnunen; Katerina Lisenkova; Marcel Merette

    2014-01-01

    To model the economics impacts of population ageing in high-income countrie by estimating the scale of required technological change. Presentation of a over-lapping generations computable general equilibrium model. Population ageing is associated with low growth and large welfare losses. The scale of technological change needed to compensate for this is very large in historical terms.

  10. Integration of the ageing workforce

    NARCIS (Netherlands)

    Krenn, M.; Oehlke, P.; Kees, H.; Leonard, L.; Wendelen, E.; Linkola, P.; Neubauer, G.; Vries, S. de; O'Kelly, K.P.

    2001-01-01

    The age structure in Europe and other industrialized countries is changing as a result of declining birth rates and continuous rise in life expectancy. This report shows the facts and figures of an ageing workforce. It also describes the predjudices, personnel policies and problems connected to the

  11. Age Differences in Mystical Experience.

    Science.gov (United States)

    Levin, Jeffrey S.

    1993-01-01

    Examined age differences in mystical experiences. According to 1988 General Social Survey (n=1,481) mystical experiences were somewhat more common in 1988 than in 1973, and deja vu, clairvoyance, and composite mysticism scores had increased with successively younger age cohorts. Private and subjective religiosity were positively related to overall…

  12. Age and Acceptance of Euthanasia.

    Science.gov (United States)

    Ward, Russell A.

    1980-01-01

    Study explores relationship between age (and sex and race) and acceptance of euthanasia. Women and non-Whites were less accepting because of religiosity. Among older people less acceptance was attributable to their lesser education and greater religiosity. Results suggest that quality of life in old age affects acceptability of euthanasia. (Author)

  13. An Educational Response to Aging.

    Science.gov (United States)

    McLain, Rosemary

    1978-01-01

    The emphasis of this article is on aging and the needs of the elderly as a basis for developing educational content in the curriculum. It includes a description of a theoretical framework developed by Abraham Maslow for a holistic approach to needs of the aged. (Editor/RK)

  14. Proverb Interpretation Changes in Aging

    Science.gov (United States)

    Uekermann, Jennifer; Thoma, Patrizia; Daum, Irene

    2008-01-01

    Recent investigations have emphasized the involvement of fronto-subcortical networks to proverb comprehension. Although the prefrontal cortex is thought to be affected by normal aging, relatively little work has been carried out to investigate potential effects of aging on proverb comprehension. In the present investigation participants in three…

  15. Mobility decline in old age

    OpenAIRE

    Rantakokko, Merja; Mänty, Minna; Rantanen, Taina

    2013-01-01

    Mobility is important for community independence. With increasing age, underlying pathologies, genetic vulnerabilities, physiological and sensory impairments, and environmental barriers increase the risk for mobility decline. Understanding how mobility declines is paramount to finding ways to promote mobility in old age.

  16. Brain aging and therapeutic interventions

    DEFF Research Database (Denmark)

    This book brings together most up-to-date information on different aspects of brain aging and on the strategies for intervention and therapy of age-related brain disorders. It includes 18 chapters by leading researchers, and each chapter is a comprehensive and critical review of the topic...

  17. Anomalous Growth of Aging Populations

    Science.gov (United States)

    Grebenkov, Denis S.

    2016-04-01

    We consider a discrete-time population dynamics with age-dependent structure. At every time step, one of the alive individuals from the population is chosen randomly and removed with probability q_k depending on its age, whereas a new individual of age 1 is born with probability r. The model can also describe a single queue in which the service order is random while the service efficiency depends on a customer's "age" in the queue. We propose a mean field approximation to investigate the long-time asymptotic behavior of the mean population size. The age dependence is shown to lead to anomalous power-law growth of the population at the critical regime. The scaling exponent is determined by the asymptotic behavior of the probabilities q_k at large k. The mean field approximation is validated by Monte Carlo simulations.

  18. Predatory senescence in ageing wolves

    Science.gov (United States)

    MacNulty, D.R.; Smith, D.W.; Vucetich, J.A.; Mech, L.D.; Stahler, D.R.; Packer, C.

    2009-01-01

    It is well established that ageing handicaps the ability of prey to escape predators, yet surprisingly little is known about how ageing affects the ability of predators to catch prey. Research into long-lived predators has assumed that adults have uniform impacts on prey regardless of age. Here we use longitudinal data from repeated observations of individually-known wolves (Canis lupus) hunting elk (Cervus elaphus) in Yellowstone National Park to demonstrate that adult predatory performance declines with age and that an increasing ratio of senescent individuals in the wolf population depresses the rate of prey offtake. Because this ratio fluctuates independently of population size, predatory senescence may cause wolf populations of equal size but different age structure to have different impacts on prey populations. These findings suggest that predatory senescence is an important, though overlooked, factor affecting predator-prey dynamics. ?? 2009 Blackwell Publishing Ltd/CNRS.

  19. The quality control theory of aging

    Directory of Open Access Journals (Sweden)

    Warren Ladiges

    2014-05-01

    Full Text Available The quality control (QC theory of aging is based on the concept that aging is the result of a reduction in QC of cellular systems designed to maintain lifelong homeostasis. Four QC systems associated with aging are 1 inadequate protein processing in a distressed endoplasmic reticulum (ER; 2 histone deacetylase (HDAC processing of genomic histones and gene silencing; 3 suppressed AMPK nutrient sensing with inefficient energy utilization and excessive fat accumulation; and 4 beta-adrenergic receptor (BAR signaling and environmental and emotional stress. Reprogramming these systems to maintain efficiency and prevent aging would be a rational strategy for increased lifespan and improved health. The QC theory can be tested with a pharmacological approach using three well-known and safe, FDA-approved drugs: 1 phenyl butyric acid, a chemical chaperone that enhances ER function and is also an HDAC inhibitor, 2 metformin, which activates AMPK and is used to treat type 2 diabetes, and 3 propranolol, a beta blocker which inhibits BAR signaling and is used to treat hypertension and anxiety. A critical aspect of the QC theory, then, is that aging is associated with multiple cellular systems that can be targeted with drug combinations more effectively than with single drugs. But more importantly, these drug combinations will effectively prevent, delay, or reverse chronic diseases of aging that impose such a tremendous health burden on our society.

  20. Space Age Archaeology

    Science.gov (United States)

    1988-01-01

    In 1985, the Egyptian Antiques Organization (EAO) asked Dr. Farouk El-Baz whether it would be possible to examine and sample the second chamber of the subterranean chamber carved in the bedrock near the Great Pyramid of Khufu in Giza, Egypt, without admitting people, air or contaminants. He felt it could by applying space technology to the task. The initial contact led to a two year project which he organized and headed a team, co-sponsored by EAO and the National Geographic Society (NGS), to apply space technology in an effort to examine and photograph the Giza Chamber. The NGS photographic division modified and tested a remotely controlled video system and a 35-millimeter camera, and developed a lighting system that would not elevate the chamber temperature. Still needed was a drill to cut through the limestone cap without using lubricants or cooling fluids that might contaminate the chamber, and an airlock that would admit the drill shaft and photo equipment but not the air. Bob Moores from Black & Decker Corporation tailored a new drill to the Giza exploration. The drill bit broke through into the chamber at a depth of 63 inches, a stainless steel tube was lowered through the airlock to take samples of the chamber air at several levels. The video camera sent images from the chamber revealing that there was a disassembled royal boat that had been there.

  1. What Causes Our Skin to Age?

    Science.gov (United States)

    ... care Younger skin Causes of aging skin Creating anti-aging plan Fillers giving patients better, longer-lasting results Maximizing anti-aging products Selecting anti-aging products Sun damage Wrinkle ...

  2. Productive Aging: A Question of Role.

    Science.gov (United States)

    Sicker, Martin; And Others

    1994-01-01

    Includes "The Paradox of Productive Aging" (Sicker); "Beyond Productive Aging" (Riley, Riley); "Changing Concepts; Visionary or Short-Sighted" (Holstein); "Making Aging Meaningful" (Glanz, Neikrug); and "Perspectives on Productive Aging from Austria, Bolivia, Denmark, Finland, Japan, Venezuela." (JOW)

  3. Health screening - men - ages 18 to 39

    Science.gov (United States)

    Health maintenance visit - men - ages 18 to 39; Physical exam - men - ages 18 to 39; Yearly exam - ... 39; Checkup - men - ages 18 to 39; Men's health - ages 18 to 39; Preventive care exam - men - ...

  4. Transgender, aging and old age - Do transgender people get old?

    Directory of Open Access Journals (Sweden)

    Pedro Paulo Sammarco Antunes

    2013-12-01

    Full Text Available This study is aimed to understand transgender aging context in Brazil. Normal and abnormal were especially created by biological sciences. For being considered deviants, transgender people are not seen as human beings. They end up living in violent environments. Their life expectancy is low. Many of them do not believe to reach old age. They face a lot of prejudice and death threat. Those who get to what we call old age are considered survivals. This investigation was able to show satisfactorily their demands and needs. To be considered visible, they have to count on public policies to give them existence since their childhood. That way, we believe they will reach what we call old age with respect and dignity, already assured by the Universal Human Rights.

  5. Practical pathology of aging mice

    Directory of Open Access Journals (Sweden)

    Piper M. M. Treuting

    2011-06-01

    Full Text Available Old mice will have a subset of lesions as part of the progressive decline in organ function that defines aging. External and palpable lesions will be noted by the research, husbandry, or veterinary staff during testing, cage changing, or physical exams. While these readily observable lesions may cause alarm, not all cause undue distress or are life-threatening. In aging research, mice are maintained until near end of life that, depending on strain and genetic manipulation, can be upwards of 33 months. Aging research has unique welfare issues related to age-related decline, debilitation, fragility, and associated pain of chronic diseases. An effective aging research program includes the collaboration and education of the research, husbandry, and veterinary staff, and of the members of the institution animal care and use committee. This collaborative effort is critical to humanely maintaining older mice and preventing excessive censorship due to non-lethal diseases. Part of the educational process is becoming familiar with how old mice appear clinically, at necropsy and histopathologically. This baseline knowledge is important in making the determination of humane end points, defining health span, contributing causes of death and effects of interventions. The goal of this paper is to introduce investigators to age-associated diseases and lesion patterns in mice from clinical presentation to pathologic assessment. To do so, we present and illustrate the common clinical appearances, necropsy and histopathological lesions seen in subsets of the aging colonies maintained at the University of Washington.

  6. Explosive and pyrotechnic aging demonstration

    Science.gov (United States)

    Rouch, L. L., Jr.; Maycock, J. N.

    1976-01-01

    The survivability was experimentally verified of fine selected explosive and pyrotechnic propellant materials when subjected to sterilization, and prolonged exposure to space environments. This verification included thermal characterization, sterilization heat cycling, sublimation measurements, isothermal decomposition measurements, and accelerated aging at a preselected elevated temperature. Temperatures chosen for sublimation and isothermal decomposition measurements were those in which the decomposition processess occurring would be the same as those taking place in real-time aging. The elevated temperature selected (84 C) for accelerated aging was based upon the parameters calculated from the kinetic data obtained in the isothermal measurement tests and was such that one month of accelerated aging in the laboratory approximated one year of real-time aging at 66 C. Results indicate that HNS-IIA, pure PbN6, KDNBF, and Zr/KC10 are capable of withstanding sterilization. The accelerated aging tests indicated that unsterilized HNS-IIA and Zr/KC104 can withstand the 10 year, elevated temperature exposure, pure PbN6 and KDNBF exhibit small weight losses (less than 2 percent) and B/KC104 exhibits significant changes in its thermal characteristics. Accelerated aging tests after sterilization indicated that only HNS-IIA exhibited high stability.

  7. Age-related skin changes

    Directory of Open Access Journals (Sweden)

    Božanić Snežana

    2012-01-01

    Full Text Available Age-related skin changes can be induced by chronological ageing, manifested in subcutaneous fat reduction, and photo-ageing eliciting increased elastotic substance in the upper dermis, destruction of its fibrilar structure, augmented intercellular substance and moderate inflammatory infiltrate. Forty-five biopsy skin samples of the sun-exposed and sun-protected skin were analyzed. The patients were both males and females, aged from 17 to 81 years. The thickness of the epidermal layers and the number of cellular living layers is greater in younger skin. The amount of keratohyaline granules is enlarged in older skin. Dermoepidermal junction is flattened and the presence of elastotic material in the dermis is pronounced with age. The amount of inflammatory infiltrate is increased, the fibrous trabeculae are thickened in older skin and the atrophy of the hypodermis is observed. Chronological ageing alters the fibroblasts metabolism by reducing their life span, capacity to divide and produce collagen. During ageing, the enlargement of collagen fibrils diminishes the skin elasticity.

  8. Women and exercise in aging

    Directory of Open Access Journals (Sweden)

    Kristina L. Kendall

    2014-09-01

    Full Text Available Aging is associated with physiological declines, notably a decrease in bone mineral density (BMD and lean body mass, with a concurrent increase in body fat and central adiposity. Interest in women and aging is of particular interest partly as a result of gender specific responses to aging, particularly as a result of menopause. It is possible that the onset of menopause may augment the physiological decline associated with aging and inactivity. More so, a higher incidence of metabolic syndrome (an accumulation of cardiovascular disease risk factors including obesity, low-density lipoprotein cholesterol, high blood pressure, and high fasting glucose has been shown in middle-aged women during the postmenopausal period. This is due in part to the drastic changes in body composition, as previously discussed, but also a change in physical activity (PA levels. Sarcopenia is an age related decrease in the cross-sectional area of skeletal muscle fibers that consequently leads to a decline in physical function, gait speed, balance, coordination, decreased BMD, and quality of life. PA plays an essential role in combating physiological decline associated with aging. Maintenance of adequate levels of PA can result in increased longevity and a reduced risk for metabolic disease along with other chronic diseases. The aim of this paper is to review relevant literature, examine current PA guidelines, and provide recommendations specific to women based on current research.

  9. NK Cells in Healthy Aging and Age-Associated Diseases

    OpenAIRE

    Xavier Camous; Alejandra Pera; Rafael Solana; Anis Larbi

    2012-01-01

    NK cells exhibit the highest cytotoxic capacity within the immune system. Alteration of their number or functionality may have a deep impact on overall immunity. This is of particular relevance in aging where the elderly population becomes more susceptible to infection, cancer, autoimmune diseases, and neurodegenerative diseases amongst others. As the fraction of elderly increases worldwide, it becomes urgent to better understand the aging of the immune system to prevent and cure the elderly ...

  10. Psychotherapy in the Internet age society

    Directory of Open Access Journals (Sweden)

    Wojciech Drath

    2015-06-01

    In the light of contemporary research, the Internet appears to be both a source of danger to mental health, but equally - a space for utilising new methods of help. Making use of these possibilities, as the author claims, goes far beyond remote psychotherapy. It requires something more from help providers: understanding and considering the new types of human relationships which develop in communication facilitated by new media.

  11. Adult Age, Gender, and Race Group Differences in Images of Aging

    Science.gov (United States)

    Foos, Paul W.; Clark, M. Cherie; Terrell, Debra F.

    2006-01-01

    Younger and older African American and Caucasian American adults, who were matched by age ("M" age = 40.63 years), completed a survey on perceptions of aging and subjective age. The 2 groups did not differ in the age they considered someone to be old ("M" age = 74.5 years). However, when asked which age was the happiest age, African Americans…

  12. Host Resistance and Immune Aging.

    Science.gov (United States)

    Bandaranayake, Thilinie; Shaw, Albert C

    2016-08-01

    Human immune system aging results in impaired responses to pathogens or vaccines. In the innate immune system, which mediates the earliest pro-inflammatory responses to immunologic challenge, processes ranging from Toll-like Receptor function to Neutrophil Extracellular Trap formation are generally diminished in older adults. Dysregulated, enhanced basal inflammation with age reflecting activation by endogenous damage-associated ligands contributes to impaired innate immune responses. In the adaptive immune system, T and B cell subsets and function alter with age. The control of cytomegalovirus infection, particularly in the T lineage, plays a dominant role in the differentiation and diversity of the T cell compartment. PMID:27394014

  13. Cellular senescence in aging primates.

    Science.gov (United States)

    Herbig, Utz; Ferreira, Mark; Condel, Laura; Carey, Dee; Sedivy, John M

    2006-03-01

    The aging of organisms is characterized by a gradual functional decline of all organ systems. Mammalian somatic cells in culture display a limited proliferative life span, at the end of which they undergo an irreversible cell cycle arrest known as replicative senescence. Whether cellular senescence contributes to organismal aging has been controversial. We investigated telomere dysfunction, a recently discovered biomarker of cellular senescence, and found that the number of senescent fibroblasts increases exponentially in the skin of aging baboons, reaching >15% of all cells in very old individuals. In addition, the same cells contain activated ataxia-telangiectasia mutated kinase and heterochromatinized nuclei, confirming their senescent status. PMID:16456035

  14. Weight and age at menarche.

    OpenAIRE

    Stark, O; Peckham, C S; Moynihan, C.

    1989-01-01

    In the National Child Development Study (1958 cohort) information on their age at menarche and their weights and heights measured at 7, 11, and 16 years was available for 4427 girls. The distribution of age at menarche was not influenced by social class. Weight adjusted for height did not play an important part in the timing of sexual maturation of the girls in the study. Relative weight (weight expressed as a percentage of standard weight) at the ages of 7 and 11 years explained only 3.2%, a...

  15. Skin anti-aging strategies

    OpenAIRE

    Ganceviciene, Ruta; Liakou, Aikaterini I.; Theodoridis, Athanasios; Makrantonaki, Evgenia; Zouboulis, Christos C.

    2012-01-01

    Skin aging is a complex biological process influenced by a combination of endogenous or intrinsic and exogenous or extrinsic factors. Because of the fact that skin health and beauty is considered one of the principal factors representing overall “well-being” and the perception of “health” in humans, several anti-aging strategies have been developed during the last years. It is the intention of this article to review the most important anti-aging strategies that dermatologists have nowadays in...

  16. AGING FACILITY CRITICALITY SAFETY CALCULATIONS

    International Nuclear Information System (INIS)

    The purpose of this design calculation is to revise and update the previous criticality calculation for the Aging Facility (documented in BSC 2004a). This design calculation will also demonstrate and ensure that the storage and aging operations to be performed in the Aging Facility meet the criticality safety design criteria in the ''Project Design Criteria Document'' (Doraswamy 2004, Section 4.9.2.2), and the functional nuclear criticality safety requirement described in the ''SNF Aging System Description Document'' (BSC [Bechtel SAIC Company] 2004f, p. 3-12). The scope of this design calculation covers the systems and processes for aging commercial spent nuclear fuel (SNF) and staging Department of Energy (DOE) SNF/High-Level Waste (HLW) prior to its placement in the final waste package (WP) (BSC 2004f, p. 1-1). Aging commercial SNF is a thermal management strategy, while staging DOE SNF/HLW will make loading of WPs more efficient (note that aging DOE SNF/HLW is not needed since these wastes are not expected to exceed the thermal limits form emplacement) (BSC 2004f, p. 1-2). The description of the changes in this revised document is as follows: (1) Include DOE SNF/HLW in addition to commercial SNF per the current ''SNF Aging System Description Document'' (BSC 2004f). (2) Update the evaluation of Category 1 and 2 event sequences for the Aging Facility as identified in the ''Categorization of Event Sequences for License Application'' (BSC 2004c, Section 7). (3) Further evaluate the design and criticality controls required for a storage/aging cask, referred to as MGR Site-specific Cask (MSC), to accommodate commercial fuel outside the content specification in the Certificate of Compliance for the existing NRC-certified storage casks. In addition, evaluate the design required for the MSC that will accommodate DOE SNF/HLW. This design calculation will achieve the objective of providing the criticality safety results to support the preliminary design of the Aging

  17. Age factors in biometric processing

    CERN Document Server

    Fairhurst, Michael

    2013-01-01

    As biometrics-based identification and identity authentication become increasingly widespread in their deployment, it becomes correspondingly important to consider more carefully issues relating to reliability, usability and inclusion. One factor which is particularly important in this context is that of the relationship between the nature of the measurements extracted from a particular biometric modality and the age of the sample donor, and the effect which age has on physiological and behavioural characteristics invoked in a biometric transaction. In Age Factors in Biometric Processing an in

  18. Detailed chronology of mid-altitude fluvial system response to changing climate and societies at the end of the Little Ice Age (Southwestern Alps and Cévennes, France)

    Science.gov (United States)

    Astrade, Laurent; Jacob-Rousseau, Nicolas; Bravard, Jean-Paul; Allignol, Françoise; Simac, L.

    2011-10-01

    Over a historical timescale, landscapes have been strongly affected by fluctuations in climate and by the impact of human societies. This study examines the historical evolution of mid-altitude fluvial systems in the Western Alps and Cévennes (SE Massif Central) in the context of marked climate and anthropogenic change at the end of the Little Ice Age (late 19th century). This work contributes to the reconstruction of river paleodynamics by investigating the nature and chronology of geomorphological changes in upper river basins. In order to produce a detailed reconstruction of hydromorphological changes, we combined two approaches: the study of historical archives and the use of bioindicators (the dating of terraces using dendrochronology and of silt benches using lichenometry in order to reconstruct the evolution of the river channels). The 19th century is a particularly propitious period for the study of surface dynamics because archives have preserved a wealth of qualitative and quantitative data concerning rivers (economic statistics, meteorological and hydrological observations, illustrative documents, descriptions by contemporary observers). It is also a period for which reliable dating methods are available for detrital deposits in rivers. The period provides new information on how the transition between the Little Ice Age and current climate conditions affected the evolution of drainage basins and stream channels by highlighting a succession of phases in the erosive process (e.g., the preparatory role of the drought of 1830-1838 in the erosion crisis of 1855-1870) and refining the chronology of events (very early onset of riverbed incision). The results highlight the effect of climate (small hydroclimatic fluctuations), amplified by strong anthropization, on the rhythm of landscape change and on the relative stabilization of the landscape at the end of the 19th century. In addition, the synchronization of phenomena on the two sides of the Rhone Valley

  19. Explaining age differences in women's emotional well-being: The role of subjective experiences of aging.

    Science.gov (United States)

    Barrett, Anne E; Toothman, Erica L

    2016-01-01

    Our study examines explanations for the "paradox" of older women's better emotional well-being compared with younger women. We consider the role of subjective experiences of aging in a society that devalues older women. Using a sample of women (n = 872) from the National Survey of Midlife Development in the United States (1995-1996 and 2004-2006), we examine the role of five components of the subjective experience of aging in explaining older women's better emotional well-being compared with younger women: age identity, conceptions of the timing of middle age, aging attitudes, aging anxieties, and self-assessed physiological changes. We find that, compared with women 50-54 years old, those 35-39 years old report lower positive affect, and those 25-49 report higher negative affect. These patterns are partially explained by younger women's greater anxiety about declines in health and attractiveness and older women's more youthful identities. Our study underscores the value of considering the implications of our ageist and sexist society for women's emotional well-being across adulthood. PMID:27029460

  20. The Development of Iron Technology in the Mediterranean Bronze Age

    OpenAIRE

    Leek, Rodney Thomas

    2014-01-01

    In the eastern Mediterranean region in the Bronze Age there were a number of elite controlled, complex societies that through cultural activities and trade and international agreements, participated in a regional exchange economy. In the transition to Iron Age there was a confusing period with wars, migrations and the collapse of most of the elite societies,. At this time, iron technology had already spread to some parts of the region. When the regional economy collapsed in c. 1200 BC it crea...

  1. [Skin aging: Molecular understanding of extrinsic and intrinsic processes].

    Science.gov (United States)

    Makrantonaki, E; Vogel, M; Scharffetter-Kochanek, K; Zouboulis, C C

    2015-10-01

    In an ever-aging society, a better understanding of the underlying mechanisms accompanying skin aging has become essential. Most age-related morphological skin changes are triggered by a combination of intrinsic factors (e.g., genetics, hormones) and extrinsic ones (e.g., ultarviolet/infrared light exposure, smoking, pollution). In this article, new insights on the latest findings regarding the pathogenesis of skin aging are summarised, addressing the extent to which the aforementioned factorsmay influence the progress of skin aging and identifying the consequences on the morphology and physiology of skin. PMID:26385893

  2. Ageing and ART: a waste of time and money?

    Science.gov (United States)

    Ng, Ernest Hung Yu; Ho, Pak Chung

    2007-02-01

    In many societies, more and more young women are delaying childbearing until the fourth decade of life. It is well known that fertility is remarkably reduced with increasing age of women in both natural conceptions and assisted reproductive technology (ART). In this chapter, the effect of ageing on the pregnancy rate in ART, and the options available to improve the reproductive outcomes in women of advanced age will be presented after understanding the mechanism of reproductive ageing and the effects of ageing on the reproductive outcomes in normal women. It is important to identify the predictive factors associated with a better treatment outcome. PMID:17049459

  3. Biological principles of aging and approaches for intervention

    DEFF Research Database (Denmark)

    Rattan, Suresh

    2011-01-01

    Aging and age related pathologies are among the main medical problems of modern societies. Although aging is generally seen as an inevitable normal developmental period, I believe that its acceptence as a disease -even though it might not- will have many pragmatical consequences and break the...... aiming to postpone aging resulted only with a few successes like caloric restriction and rapamycin in model animals. Therefore we likely need a paradigm shift in the future. Therefore, in this book extreme plant longevity/plant aging and traditional medicine were emphasized as new areas to focus on in...

  4. Reflections of Urban Planning on the Context of an Aging Society%老龄化社会背景下对我国城市规划的思考

    Institute of Scientific and Technical Information of China (English)

    李小云; 田银生; 陈锦棠

    2011-01-01

    从我国老龄化的社会背景出发,分析了城市“人口红利”优势的弱化、老龄产业的兴起与发展、老年住房供需矛盾突出、老年社会角色的延续与转换等相关性特征.认为我国城市管理者或规划师应前瞻性地认识中国老龄化社会发展趋势,对城市规划从城市发展策略、用地布局、交通组织、社区规划、公众参与等过程作出应对性的调整,制定适合老年主体人群的城市规划体系,以维护社会各阶层的合法利益,体现出城市规划的公共政策性.%This paper analyses relativity characters of the Chinese aging society, including the reducing of demographic dividend, the emergence and development of elderly industry, the contradiction between supply and demand of elderly housing, and the continuation of elder social roles. The authors consider that in order to safeguard the legitimate interests of all sectors of society and reflect the public policy of urban planning, discussion should focus on establishing urban planning system for elderly by regulating the city's development strategy, land layout, traffic organization, community planning, and public participation, etc.

  5. Photoplethysmogram reflection index and aging

    Science.gov (United States)

    Qawqzeh, Yousef K.; Reaz, M. B. I.; Maskon, O.; Chellappan, Kalaivani; Ali, M. A. M.

    2011-10-01

    This study conducted to investigate and study the effect of aging on Photoplethysmogram (PPG) signal and the effects of aging on the calculations of reflection index (RI). The results showed that PPG is highly affected by aging which noteworthy to be observed by the variations of PPG contour. Since we advance in age, PPG becomes more rounded which in turn make PPG inflection point and dicrotic notch less pronounced. As a conclusion, RI may provide a window to small and medium arteries compliance and it can be a measure of small and medium arteries stiffness. When small and medium arteries start stiffening, early detection of atherosclerosis in sub-clinical settings can be investigated and detected.

  6. Nutrition and the Aging Eye

    Science.gov (United States)

    ... turn Javascript on. Feature: Vision Nutrition and the Aging Eye Past Issues / Winter 2012 Table of Contents ... and showed that an experimental combination of three anti-oxidant vitamins (C, E, and beta carotene) and ...

  7. School-age children development

    Science.gov (United States)

    ... work, free play, and structured activities. School-age children should participate in family chores such as setting the table and cleaning up. Limit screen time (television and other media) to 2 hours a day.

  8. Nutrition and the Aging Eye

    Science.gov (United States)

    ... Issue Past Issues Special Section Nutrition and the Aging Eye Past Issues / Winter 2007 Table of Contents ... study showed that an experimental combination of three anti-oxidant vitamins (C, E and beta carotene) and ...

  9. Small for gestational age (SGA)

    Science.gov (United States)

    ... is called intrauterine growth restriction. The most common definition of small for gestational age (SGA) is a ... M. is also a founding member of Hi-Ethics and subscribes to the principles of the Health ...

  10. Aging Logarithmic Galilean Field Theories

    CERN Document Server

    Hyun, Seungjoon; Kim, Bom Soo

    2013-01-01

    We analytically compute correlation and response functions of scalar operators for the systems with Galilean and corresponding aging symmetries for general spatial dimensions $d$ and dynamical exponent $z$, along with their logarithmic and logarithmic squared extensions, using the gauge/gravity duality. These non-conformal extensions of the aging geometry are marked by two dimensionful parameters, eigenvalue $\\mathcal M$ of an internal coordinate and aging parameter $\\alpha$. We further perform systematic investigations on two-time response functions for general $d$ and $z$, and identify the growth exponent as a function of the scaling dimensions $\\Delta$ of the dual field theory operators and aging parameter $\\alpha$ in our theory. The initial growth exponent is only controlled by $\\Delta$, while its late time behavior by $\\alpha$ as well as $\\Delta$. These behaviors are separated by a time scale order of the waiting time. We attempt to make contact our results with some field theoretical growth models, such...

  11. Age-differentiated work systems

    CERN Document Server

    Frieling, Ekkehart; Wegge, Jürgen

    2013-01-01

    The disproportionate aging of the population of working age in many nations around the world is a unique occurrence in the history of humankind. In the light of demographic change, it is becoming increasingly important to develop and use the potential of older employees. This edited volume Age-differentiated Work Systems provides a final report on a six-year priority program funded by the German Research Foundation (DFG) and presents selected research findings of 17 interdisciplinary project teams. The idea is that it will serve both as a reference book and overview of the current state of research in ergonomics, occupational psychology and related disciplines. It provides new models, methods, and procedures for analyzing and designing age-differentiated work systems with the aim of supporting subject matter experts from different areas in their decisions on labor and employment policies. Therefore over 40 laboratory experiments involving 2,000 participants and 50 field studies involving over 25,000 employees...

  12. 7 Steps to Aging Well

    Science.gov (United States)

    ... Past Issues Special Section 7 Steps to Aging Well Past Issues / Winter 2007 Table of Contents For ... the risk of death from automobile crashes as well as recreational and on-the-job injuries. What ...

  13. Aging changes in vital signs

    Science.gov (United States)

    ... Vital signs include body temperature, heart rate (pulse), breathing rate, and blood pressure. As you age, your vital ... symptoms and signs of infection. HEART RATE AND BREATHING RATE As you grow older, your pulse rate is ...

  14. Comparative evaluation of dental age, bone age, and chronological age in the human immunodeficiency virus positive children

    OpenAIRE

    Vinod Kumar; Kavitha Patil; Munoli, Karishma B

    2014-01-01

    Background and Objective: The knowledge of bone age and dental age is of great importance for pediatrician and pediatric dentist. It is essential for pediatric dentist to formulate treatment plan and it is a source of complementary information for pediatrician. There are few studies in literature, which showed the relationship between dental age, bone age and chronological age in HIV-positive children. Therefore, objective of this study was to determine and compare dental age, bone age and ch...

  15. Subjective wellbeing, health, and ageing.

    Science.gov (United States)

    Steptoe, Andrew; Deaton, Angus; Stone, Arthur A

    2015-02-14

    Subjective wellbeing and health are closely linked to age. Three aspects of subjective wellbeing can be distinguished-evaluative wellbeing (or life satisfaction), hedonic wellbeing (feelings of happiness, sadness, anger, stress, and pain), and eudemonic wellbeing (sense of purpose and meaning in life). We review recent advances in the specialty of psychological wellbeing, and present new analyses about the pattern of wellbeing across ages and the association between wellbeing and survival at older ages. The Gallup World Poll, a continuing survey in more than 160 countries, shows a U-shaped relation between evaluative wellbeing and age in high-income, English speaking countries, with the lowest levels of wellbeing in ages 45-54 years. But this pattern is not universal. For example, respondents from the former Soviet Union and eastern Europe show a large progressive reduction in wellbeing with age, respondents from Latin America also shows decreased wellbeing with age, whereas wellbeing in sub-Saharan Africa shows little change with age. The relation between physical health and subjective wellbeing is bidirectional. Older people with illnesses such as coronary heart disease, arthritis, and chronic lung disease show both increased levels of depressed mood and impaired hedonic and eudemonic wellbeing. Wellbeing might also have a protective role in health maintenance. In an analysis of the English Longitudinal Study of Ageing, we identify that eudemonic wellbeing is associated with increased survival; 29·3% of people in the lowest wellbeing quartile died during the average follow-up period of 8·5 years compared with 9·3% of those in the highest quartile. Associations were independent of age, sex, demographic factors, and baseline mental and physical health. We conclude that the wellbeing of elderly people is an important objective for both economic and health policy. Present psychological and economic theories do not adequately account for the variations in patterns

  16. Mitigating aging in CANDU plants

    International Nuclear Information System (INIS)

    Aging degradation is a phenomenon we all experience throughout life, both on a personal basis and in business. Many industries have been successful in postponing the inevitable impact on their related systems and components through programs to maintain long-term reliability, maintainability and safety. However, this has not always been the case for nuclear power. While all power plants are experiencing the world trend of increasing operating costs with age, few (if any) have been able to fully define the parameters that solve the aging equation, particularly in relation to major components. Inspection and preventive maintenance have not been effective in predicting life-limiting degradation and failure. In CANDU nuclear plants, utilities are taking a comprehensive approach in dealing with the aging problem. Programs have been established to identify the current condition and degradation mechanisms of critical components, the failure of which would impact negatively on station competitiveness and safety. These include subcomponents under the general headings of reactor components, civil structures, piping (nuclear and conventional), steam generators, turbines and cables. In support of these efforts, R and D projects have been defined under the CANDU Owners Group to deal with generic issues on aging common to its members (e.g., investigation of degradation mechanisms, development of tools and techniques to mitigate the effects of aging, etc.). This paper describes recent developments of this cost-shared program with specific reference to concrete aging and crack repairs, flow-assisted corrosion in piping, elastomer service life, cable aging, degradation mechanisms in steam generators and lubricant breakdown. (author)

  17. Optimal age specific income taxation

    OpenAIRE

    LOZACHMEUR, Jean-Marie

    2002-01-01

    This paper studies optimal earnings taxation in a three period life cycle model where the taxes raised to finance an exogenous amount of public expenditure are allowed to be differentiated across ages. Agents choose their level of education when young and their age of retirement when old. We first look at the problem of optimal taxation when the young can borrow and then turn to the case where young face borrowing constraints. It is shown that, without borrowing constraints, a first best opti...

  18. Demographic Consequences of Defeating Aging

    OpenAIRE

    Gavrilov, Leonid A.; Gavrilova, Natalia S.

    2010-01-01

    A common objection against starting a large-scale biomedical war on aging is the fear of catastrophic population consequences (overpopulation). This fear is only exacerbated by the fact that no detailed demographic projections for radical life extension scenario have been conducted so far. This study explores different demographic scenarios and population projections, in order to clarify what could be the demographic consequences of a successful biomedical war on aging. A general conclusion o...

  19. Does Retirement Age Impact Mortality?

    OpenAIRE

    Hernaes, Erik; Markussen, Simen; Piggott, John; Vestad, Ola

    2012-01-01

    This paper studies the relationship between retirement and mortality, using a unique administrative data set covering the full population of Norway. We make use of a series of retirement policy changes in Norway, which reduced the retirement age for a group of workers but not for others. By employing a difference-in-differences framework based on monthly birth cohort and treatment group status we first establish that the early retirement program significantly reduced the retirement age - this...

  20. Changing how we view aging.

    Science.gov (United States)

    Holland, Jimmie; Greenstein, Mindy

    2015-05-01

    It is time for medicine, particularly geriatric medicine, to incorporate an understanding of how the psychological aspects of aging interact with cancer. The impact has both negative elements--for example, the added stresses of other losses or comorbid ailments that come with age--and positive elements, particularly a lifetime of honing character strengths on which to draw during a challenging time. PMID:25944028

  1. Physical fitness, aging, and sexuality.

    OpenAIRE

    Bortz, W M; D. H. Wallace

    1999-01-01

    Sexuality is a major quality-of-life issue, even into advanced age. Although relatively few studies have addressed sexuality, most studies have emphasized the decline in both sexual performance and satisfaction with aging. In an effort to assess possible positive modifiers of the decline, we included questions concerning sexuality in a multipurpose 90-item questionnaire submitted to members of the Fifty Plus Fitness Association based in Stanford, California. This group is unique in its commit...

  2. Transcriptomic profiling of cartilage ageing

    OpenAIRE

    Mandy Jayne Peffers; Xuan Liu; Peter David Clegg

    2014-01-01

    The musculoskeletal system is severely affected by the ageing process, with many tissues undergoing changes that lead to loss of function and frailty. Articular cartilage is susceptible to age related diseases, such as osteoarthritis. Applying RNA-Seq to young and old equine cartilage, we identified an over-representation of genes with reduced expression relating to extracellular matrix, degradative proteases, matrix synthetic enzymes, cytokines and growth factors in cartilage from older dono...

  3. Persuasive Technologies for Active Ageing

    OpenAIRE

    Khaghani Far, Iman

    2016-01-01

    Most of the world countries are challenged with a large ageing population who spend most of their time at home and are mostly sedentary (8.5 hours per day as of today). Sedentary behavior and physical inactivity affect the social, physical and mental states of people leading to social isolation and physical declines and hence an ideal candidate for chronic and degenerative diseases. To maintain an active aging process (healthy state of physical, mental and social wellbeing), regular and...

  4. [Impact of aging on sexuality].

    Science.gov (United States)

    Degauquier, C; Absil, A-S; Psalti, I; Meuris, S; Jurysta, F

    2012-01-01

    Numerous authors on sexual behaviors have studied the link between the persistence of a sexually active life and progressive aging. The knowledge of sexual health in the elderly has shown that biological sexual aging is extremely diverse and heterogeneous in men as well as in women, and contradicts the stereotype of age that would inevitably alter the sexual biological response in each human. Sexual diseases (lubrication, dyspareunia, erectile dysfunction, inability to achieve orgasm) and diseases of aging that impact sexual function have a growing incidence but don't never touch 100% of individuals. There is a decline in sexual interest correlated with the life-span, but the negative effects of age on desire are related to health problems. Moreover, sexual desire is more correlated with personal attitudes toward sexuality than with biological factors and diseases. Several predictors account for the pursuit of an active sexuality (including the presence of a partner, good health, having good sexual self-esteem, enjoyable past experience, an attitude that values the importance of sex in couple relationship), but the most decisive factor to successfully face the specific markers of aging is the ability to adapt to a more sensory sexuality, less focused on performance and coitus. PMID:22891587

  5. Chromospheric activity as age indicator

    CERN Document Server

    Pace, Giancarlo

    2013-01-01

    Chromospheric activity has been calibrated and widely used as age indicator. However, it has been suggested that the viability of such an age indicator is, in the best case, limited to stars younger than about 1.5 Gyr. I aim to define the age range for which chromospheric activity is a robust astrophysical clock. I collected literature measurements of the S-index in field stars, which is a measure of the strength of the H and K lines of the Ca II and a proxy for chromospheric activity, and exploited the homogeneous database of temperature and age determinations for field stars provided by the Geneva-Copenhagen survey of the Solar neighbourhood. Field data, inclusive data previously used to calibrate chromospheric ages, confirm the result found using open cluster data, i.e. there is no decay of chromospheric activity after about 2 Gyr. The only existing indication supporting the viability of chromospheric ages larger than 2 Gyr, is the similarity of chromospheric activity levels in the components of 35 dwarf b...

  6. Brain trace elements and aging

    International Nuclear Information System (INIS)

    Degenerative mechanisms involved in the aging process of the brain are to a certain extent counteracted by repair mechanisms. In both degenerative and recovery processes, trace elements are involved. The present study focused on the role of two minor (i.e., K and Ca) and six trace elements (i.e., Mn, Fe, Cu, Zn, Se and Rb) in the aging process. The elements were determined by PIXE in cerebral cortex and white matter, basal ganglia, brainstem and cerebellar cortex of 18 postmortem human brains, from persons without a history of neurologic or psychiatric disease who deceased between the age of 7 and 79. This age range allowed us to study the relationship between elemental concentrations and age. The most prominent findings were a concentration decrease for K and Rb and a concentration increase for the elements Ca, Fe, Zn and Se. The study supports recent findings that Ca and Fe are involved in brain degenerative processes initiated by oxygen free radicals, whereas Zn and Se are involved in immunological reactions counteracting the aging process

  7. Aging Men and Prostate Cancer

    Directory of Open Access Journals (Sweden)

    Thompson B

    2015-01-01

    Full Text Available Prostate cancer (PCa is one of the most commonly diagnosed cancers in men worldwide and its incidence increases with age, mainly affecting elderly men aged 60 and above. Factors known to be associated with the development and progression of PCa are age, family history, and race/ethnicity, with age being the most important factor. The reasons for the increased incidence and mortality due to prostate cancer in elderly men are not entirely clear. Continued exposure to environmental and dietary factors may lead to accumulation of genetic and epigenetic changes over the life-span, leading to altered expression and/or activity of tumor promoter and tumor suppressor genes. Changing levels of endogenous hormones (like androgens and metabolism in elderly men may also play a role in the development of prostate cancers which may be further influenced by testosterone replacement therapy. For many decades now preventative strategies and treatments such as radiation therapy or hormone therapy, and others have been administered to manage PCa; however current studies and evidence suggest that PCa is undertreated in elderly men, despite evidence of efficacy of these treatments, which leads to higher prevalence of mortality in this age group. Studies involving basic research, preventative and management strategies are still underway to understand the mechanisms of PCa development in elderly men and treatment of this disease in ageing male population.

  8. Nutrients for the aging eye

    Directory of Open Access Journals (Sweden)

    Rasmussen HM

    2013-06-01

    Full Text Available Helen M Rasmussen,1 Elizabeth J Johnson2 1Educational Studies, Lesley University, Cambridge, MA, USA; 2Carotenoid and Health Laboratory, Jean Mayer US Department of Agriculture Human Nutrition Research Center on Aging at Tufts University, Boston, MA, USA Abstract: The incidence of age-related eye diseases is expected to rise with the aging of the population. Oxidation and inflammation are implicated in the etiology of these diseases. There is evidence that dietary antioxidants and anti-inflammatories may provide benefit in decreasing the risk of age-related eye disease. Nutrients of interest are vitamins C and E, β-carotene, zinc, lutein, zeaxanthin, and the omega-3 fatty acids eicosapentaenoic acid and docosahexaenoic acid. While a recent survey finds that among the baby boomers (45–65 years old, vision is the most important of the five senses, well over half of those surveyed were not aware of the important nutrients that play a key role in eye health. This is evident from a national survey that finds that intake of these key nutrients from dietary sources is below the recommendations or guidelines. Therefore, it is important to educate this population and to create an awareness of the nutrients and foods of particular interest in the prevention of age-related eye disease. Keywords: nutrition, aging, eye health

  9. Molecular Mechanisms of Cardiovascular Aging

    Directory of Open Access Journals (Sweden)

    Anna Meiliana

    2013-12-01

    Full Text Available BACKGROUND: The average lifespan of humans is increasing, and with it the percentage of people entering the 65 and older age group is growing rapidly and will continue to do so in the next 20 years. Within this age group, cardiovascular disease will remain the leading cause of death, and the cost associated with treatment will continue to increase. Aging is an inevitable part of life and unfortunately poses the largest risk factor for cardiovascular disease. CONTENT: We provide an overview of some of the molecular mechanisms involved in regulating lifespan and health, including mitochondria, telomeres, stem cells, sirtuins, Adenosine Monophosphate-activated Protein Kinase, Mammalian Target of Rapamycin and Insulin-like Growth Factor 1. We also provide future perspectives of lifespan and health, which are intimately linked fields. SUMMARY: Aging remains the biggest non-modifiable risk factor for cardiovascular disease. The biological, structural and mechanical changes in senescent cardiovascular system are thought to contribute in increasing incidence of cardiovascular disease in aging. Understanding the mechanisms contributing to such changes is therefore crucial for both prevention and development of treatment for cardiovascular diseases. KEYWORDS: cardiovascular aging, mitochondria, telomeres, sirtuin, stem cells.

  10. The changing understanding of ageing. Part 3: Diseases of ageing

    Directory of Open Access Journals (Sweden)

    Dennis F. Lawler

    2011-09-01

    Full Text Available This third and final paper in this series considers ageing mechanisms across species, with emphasis on conserved metabolic pathways that relate to disease. The growth hormone (GH-insulin-like growth factor (IGF-1-insulin axis continues as an example of how critical pathways might relate to longevity and senescence. Aligning theory, research outcomes and clinical investigations at the levels of the cell, organism and population, is suggested as a means by which to consider the many complexities of the ageing process in an orderly fashion. A contentious debate revolves around whether ageing is purely a combined effect of stochastic events on residual programming relating to reproductive robustness, or whether ageing itself is programmed by natural selection. Emerging data indicate that the influence of genetic programming on specific late-life diseases, and even individual tissue pathologies, will probably need to be reconsidered in the light of newer theoretical possibilities. In particular, the evidence that late life and its diseases are objects of considerable investment of energy challenges theory that couples longevity with reproduction. Furthermore, the author suggests that ageing may have evolved at least partly as a means of niche preservation for contemporaries and for progeny.

  11. Proinflammatory cytokines, aging, and age-related diseases.

    Science.gov (United States)

    Michaud, Martin; Balardy, Laurent; Moulis, Guillaume; Gaudin, Clement; Peyrot, Caroline; Vellas, Bruno; Cesari, Matteo; Nourhashemi, Fati

    2013-12-01

    Inflammation is a physiological process that repairs tissues in response to endogenous or exogenous aggressions. Nevertheless, a chronic state of inflammation may have detrimental consequences. Aging is associated with increased levels of circulating cytokines and proinflammatory markers. Aged-related changes in the immune system, known as immunosenescence, and increased secretion of cytokines by adipose tissue, represent the major causes of chronic inflammation. This phenomenon is known as "inflamm-aging." High levels of interleukin (IL)-6, IL-1, tumor necrosis factor-α, and C-reactive protein are associated in the older subject with increased risk of morbidity and mortality. In particular, cohort studies have indicated TNF-α and IL-6 levels as markers of frailty. The low-grade inflammation characterizing the aging process notably concurs at the pathophysiological mechanisms underlying sarcopenia. In addition, proinflammatory cytokines (through a variety of mechanisms, such as platelet activation and endothelial activation) may play a major role in the risk of cardiovascular events. Dysregulation of the inflammatory pathway may also affect the central nervous system and be involved in the pathophysiological mechanisms of neurodegenerative disorders (eg, Alzheimer disease).The aim of the present review was to summarize different targets of the activity of proinflammatory cytokines implicated in the risk of pathological aging. PMID:23792036

  12. Experiencing simulated aging improves knowledge of and attitudes toward aging.

    Science.gov (United States)

    Yu, Chiu-Yen; Chen, Kuei-Min

    2012-05-01

    Nursing assistants provide 90% of the functional and psychosocial care of older adults in nursing homes. Without knowledge of the normal physical changes of aging, it would be difficult to provide them with appropriate quality care. This quasi-experimental study aimed to test the effects of the Elderly Simulation Program on nursing assistants' knowledge about aging, attitudes toward older adults, and the motivation to care for older adults in nursing homes. The program has two parts: a 1-hour lecture about aging changes and a 1-hour simulation of the roles of an older adult, a caregiver, and a "rusher" (20 minutes for each role). A convenience sample of 83 full-time nursing assistants was recruited from nursing homes in Taiwan. The participants were assigned to an experimental (n = 43) or a control group (n = 40). The experimental group received the Elderly Simulation Program intervention, whereas the control group did not participate in any educational programs. Data were collected before the intervention and 4 wk after the program was completed. Results indicated that 4 wk after the intervention, the experimental group participants' knowledge about aging and attitudes toward older adults had significantly improved (all P job continuing education of nursing assistants in long-term care facilities to enhance their knowledge about aging and their attitudes towards older adults. PMID:22568571

  13. Blue Journal Conference. Aging and Susceptibility to Lung Disease

    OpenAIRE

    Thannickal, Victor J.; Murthy, Mahadev; Balch, William E.; Chandel, Navdeep S.; Meiners, Silke; Eickelberg, Oliver; Selman, Moisés; Pardo, Annie; White, Eric S.; Levy, Bruce D.; Busse, Paula J; Tuder, Rubin M.; Veena B Antony; Sznajder, Jacob I.; Budinger, G. R. Scott

    2015-01-01

    The aging of the population in the United States and throughout the developed world has increased morbidity and mortality attributable to lung disease, while the morbidity and mortality from other prevalent diseases has declined or remained stable. Recognizing the importance of aging in the development of lung disease, the American Thoracic Society (ATS) highlighted this topic as a core theme for the 2014 annual meeting. The relationship between aging and lung disease was discussed in several...

  14. Ageing management for systems, structures and components

    International Nuclear Information System (INIS)

    During operation, ageing will influence the quality of systems, structures and components (SSC). Experts make a distinction between the phenomena of conceptional ageing, technological ageing and physical ageing. The quality of SSC may be influenced by conceptional ageing, quality, technological or physical ageing. The contribution outlines the preconditions for a comprehensive, standardized ageing management of nuclear power stations in the Federal Republic of Germany. (orig.)

  15. Filter-adsorber aging assessment

    International Nuclear Information System (INIS)

    An aging assessment of high-efficiency particulate (HEPA) air filters and activated carbon gas adsorption units was performed by the Pacific Northwest Laboratory as part of the U.S. Nuclear Regulatory Commission's (USNRC) Nuclear Plant Aging Research (NPAR) Program. This evaluation of the general process in which characteristics of these two components gradually change with time or use included the compilation of information concerning failure experience, stressors, aging mechanisms and effects, and inspection, surveillance, and monitoring methods (ISMM). Stressors, the agents or stimuli that can produce aging degradation, include heat, radiation, volatile contaminants, and even normal concentrations of aerosol particles and gasses. In an experimental evaluation of degradation in terms of the tensile breaking strength of aged filter media specimens, over forty percent of the samples did not meet specifications for new material. Chemical and physical reactions can gradually embrittle sealants and gaskets as well as filter media. Mechanisms that can lead to impaired adsorber performance are associated with the loss of potentially available active sites as a result of the exposure of the carbon to airborne moisture or volatile organic compounds. Inspection, surveillance, and monitoring methods have been established to observe filter pressure drop buildup, check HEPA filters and adsorbers for bypass, and determine the retention effectiveness of aged carbon. These evaluations of installed filters do not reveal degradation in terms of reduced media strength but that under normal conditions aged media can continue to effectively retain particles. However, this degradation may be important when considering the likelihood of moisture, steam, and higher particle loadings during severe accidents and the fact it is probable that the filters have been in use for an extended period

  16. Correlation between Chronological Age, Dental Age and Skeletal Age among Monozygoyic and Dizygotic Twins

    OpenAIRE

    Gupta, Mohit; Divyashree, R; Abhilash, PR; A Bijle, Mohammed Nadeem; Murali, KV

    2013-01-01

    Introduction: Chronological age, dental development, height and weight measurements, sexual maturation characteristics and skeletal age are some biological indicators that have been used to identify time of growth. Many researchers have agreed that skeletal maturity is closely related to the craniofacial growth, and bones of hand and wrist are reliable parameters in assessing it. The complete hand and wrist radiograph involves 30 bones and assessment of these bones is one elaborate task. The ...

  17. NPP Krsko Aging Management Program

    International Nuclear Information System (INIS)

    As a part of Periodic Safety Review Program (PSR) NEK will review and perform some activities related to Equipment Qualification (EQ) and Aging Management Program (AMP). (EQ) and AMP are safety factors, which need to be assessed during PSR. The goal of PSR and AMP is to determine aging effects and give the conclusion whether the plant has been managed to control aging related degradations and that safety margins are maintained. The parallel goal is also to establish AMP for future plant operation and provide basis for possible Life Extension Program. NEK will develop NEK Aging and Life Cycle Management Program, similar by format and content to one determined by License Renewal program. The bases are in 10CFR54, and NEI 95-10 Industry Guidelines for 10 CFR 54 implementation. The process of establishment the AMP is to be done in two steps. The first step is dealing with SSC's (Systems Structures and Components) scoping and screening and identification of TLAA's (Time Limited Aging Analyses). That means, that a database of all SSC's and TLAA's will be created and then evaluated within AMP program. Based on the scope in first phase an evaluation will be performed in step two. NEK will maintain AMP program as a living program that may be also used for Life Extension and Life Cycle Management. This paper will present and describe AMP, scoping and screening process and the results achieved through the first phase of the project.(author)

  18. Radiogenic age and isotopic studies

    International Nuclear Information System (INIS)

    This is one of an annual collection of reports presenting data from the Geochronology Section of the Continental Geoscience Division of the Geological Survey of Canada (GSC). The main purpose of this collection is to make geochronological and other radiogenic isotope data produced by the section available promptly to the geological community. Reports make full presentation of the data, relate these to field settings and make comparatively short interpretations. Other geochronological and isotope data produced in the laboratory but published in outside journals or separate GSC publications are summarized at the end of this report. Reports in this issue cover methods for Rb-Sr and Sm-Nd isotopic analyses; 40Ar-39Ar ages for the New Quebec Crater and for basaltic rocks; U-Pb ages for a differentiated mafic sill in the Ogilvie Mountains, plutonic rocks in the Contwoyto-Nose Lakes are, zircons from the Anton Complex, the Clinton-Colden gabbro-anorthosite intrusion, the Himag plutonic suite, the Campbell granite, the Central Gneiss Belt, Silurian granites, a metarhyolite, plagiogranite and gabbro, and the Wage shear zone; Rb-Sr ages for granitic rocks; K-Ar and Rb-Sr geochronology of granites; a compilation of K-Ar ages; ages of archean and proterozoic mylonites and pre-Misi granitoid domes; and reconnaissance geochronology of Baffin Island

  19. Ageing and kidney: a primer

    Directory of Open Access Journals (Sweden)

    Suneetha P

    2015-10-01

    Full Text Available Ageing is an inevitable process that affects all organs and kidneys are no way an exception. There is an urgent need to understand ageing as a holistic process. The changes occurring in ageing kidneys resemble to those occurring in chronic kidney disease. However, many differences exist between them. Old age is a risk factor for acute kidney injury and increased risk of urinary tract infections and asymptomatic bacteriruria, Serum creatinine is a suboptimal indicator of renal function in the elderly because loss of muscle mass in elderly decreases creatinine production. Serum cystatinc measurement, with reference values adjusted for age represents a promising marker to measure renal function in the elderly. The default management strategy for renal failure in elderly is more of conservative in developing countries when compared to developed countries where there is changing trend from conservative to initiation of renal replacement therapy. The decision when to initiate renal replacement therapy is more challenging. Haemodialysis or peritoneal dialysis each has its own advantages and disadvantages.

  20. Aging fingerprints in combustion particles

    Directory of Open Access Journals (Sweden)

    V. Zelenay

    2011-05-01

    Full Text Available Soot particles can significantly influence the Earth's climate by absorbing and scattering solar radiation as well as by acting as cloud condensation nuclei. However, despite their environmental (as well as economic and political importance, the way these properties are affected by atmospheric processing is still a subject of discussion. In this work, soot particles emitted from two different cars, a EURO 2 transporter, a EURO 3 passenger vehicle, and a wood stove were investigated on a single-particle basis. The emitted exhaust, including the particulate and the gas phase, was processed in a smog chamber with artificial solar radiation. Single particle specimens of both unprocessed and aged soot were characterized using x-ray absorption spectroscopy and scanning electron microscopy. Comparison of the spectra from the unprocessed and aged soot particles revealed changes in the carbon functional group content, such as that of carboxylic carbon, which can be ascribed to both the condensation of secondary organic compounds on the soot particles and oxidation of primary soot particles upon photochemical aging. Changes in the morphology and size of the single soot particles were also observed upon aging. Furthermore, we show that the soot particles take up water in humid environments and that their water uptake capacity increases with photochemical aging.

  1. 29 CFR 570.121 - Age certificates.

    Science.gov (United States)

    2010-07-01

    ... Provisions of the Fair Labor Standards Act of 1938, as Amended Oppressive Child Labor § 570.121 Age... person is above the oppressive child labor age.” An age certificate is a statement of a minor's age... 29 Labor 3 2010-07-01 2010-07-01 false Age certificates. 570.121 Section 570.121 Labor...

  2. Epigenetic drift in the aging genome

    DEFF Research Database (Denmark)

    Tan, Qihua; Heijmans, Bastiaan T; Hjelmborg, Jacob V B;

    2016-01-01

    BACKGROUND: Current epigenetic studies on aging are dominated by the cross-sectional design that correlates subjects' ages or age groups with their measured epigenetic profiles. Such studies have been more aimed at age prediction or building up the epigenetic clock of age rather than focusing on ...

  3. Review of wire chamber aging

    International Nuclear Information System (INIS)

    This paper makes an overview of the wire chamber aging problems as a function of various chamber design parameters. It emphasizes the chemistry point of view and many examples are drawn from the plasma chemistry field as a guidance for a possible effort in the wire chamber field. The paper emphasizes the necessity of variable tuning, the importance of purity of the wire chamber environment, as well as it provides a practical list of presently known recommendations. In addition, several models of the wire chamber aging are qualitatively discussed. The paper is based on a summary talk given at the Wire Chamber Aging Workshop held at LBL, Berkeley on January 16-17, 1986. Presented also at Wire Chamber Conference, Vienna, February 25-28, 1986. 74 refs., 18 figs., 11 tabs

  4. Aging, cellular senescence, and cancer.

    Science.gov (United States)

    Campisi, Judith

    2013-01-01

    For most species, aging promotes a host of degenerative pathologies that are characterized by debilitating losses of tissue or cellular function. However, especially among vertebrates, aging also promotes hyperplastic pathologies, the most deadly of which is cancer. In contrast to the loss of function that characterizes degenerating cells and tissues, malignant (cancerous) cells must acquire new (albeit aberrant) functions that allow them to develop into a lethal tumor. This review discusses the idea that, despite seemingly opposite characteristics, the degenerative and hyperplastic pathologies of aging are at least partly linked by a common biological phenomenon: a cellular stress response known as cellular senescence. The senescence response is widely recognized as a potent tumor suppressive mechanism. However, recent evidence strengthens the idea that it also drives both degenerative and hyperplastic pathologies, most likely by promoting chronic inflammation. Thus, the senescence response may be the result of antagonistically pleiotropic gene action. PMID:23140366

  5. Lesbians discuss beauty and aging.

    Science.gov (United States)

    Thompson, K M; Brown, N; Cassidy, J; Gentry, J H

    1999-01-01

    ABSTRACT Two conversations with three aging lesbians are presented to identify and explore different definitions of beauty and how these definitions change and are influenced by age. The three women interviewed believe beauty is more than skin deep, yet they differ regarding specific components of beauty. Two believe that their definition of beauty has changed as they age and one believes that her definition has remained basically unchanged through the years. Topics of discussion include: beauty role models, the impact of the American beauty standard on their self-esteem, and what they look for in potential partners. Through these women's diverse opinions on how beauty is defined and experienced by older lesbians, we see that there is no one perspective representing all older women. PMID:24786423

  6. [IMPACT OF AGING IN PSYCHIATRY].

    Science.gov (United States)

    Rubin, Romina; Jauregui, Ricardo

    2015-01-01

    The changes associated with aging influence the clinical presentation and treatment approach of psychiatric illness. Several psychiatric disorders are common in old age as depression or set of diseases with cognitive impairment requiring geriatric knowledge. In many countries psychiatry of the elderly are called psychogeriatric. Regardless of the name objective of this article is to convey that the psychiatrist who treats patients over 65 years with multiple disorders, with frailty social problems and polypharmacy should have some tools in addition to the thorough understanding of psychiatric illness itself. Teamwork, meet physiological changes of aging and how these affect the response to drugs, atypical presentation of illness and keep in mind the importance of psychosocial and environmental issues both in presentation and in addressing and monitoring of disease. PMID:26650408

  7. Ageing Holocaust survivors in Australia.

    Science.gov (United States)

    Paratz, Elizabeth D; Katz, Benny

    2011-02-21

    In recent years, a phenomenon of "late effects of the Holocaust" has emerged, with impacts on the psychological and physical health of ageing Holocaust survivors. As Holocaust survivors age, they may experience heightened anxiety around normal processes of ageing, worsened post-traumatic stress disorder with cognitive decline, and fear of the medical system. Holocaust survivors are at increased risk of osteoporosis, cardiometabolic disease due to hypothalamic-pituitary-adrenal axis dysfunction, cancer, and sequelae of Nazi medical experiments. From existing medical literature on this topic, practical principles of management are derived to create a framework for sensitive medical management of Holocaust survivors in Australia. The issues discussed are also relevant to the wider geriatric refugee or prisoner-of-war experience. PMID:21401461

  8. The age of the elements

    International Nuclear Information System (INIS)

    The paper is devoted to nuclear cosmochronology. The age of the Universe is estimated with the aid of radioactive nuclear-nuclear chronometers (NC). For calculations it is required that the proportion in which the appropriate pair of NC is at present ('relative abundance') and the proportion for the moment of their formation ('relative production') should be known. A short description is given of production of elements in the process of star evolution. The 'relative production' is calculated theoretically. The relative abundance is determined from experiments, mainly from meteorites. Recentl Lunar rocks have been also coming into use. The following elements are chosen as pairs of chronometers: Th-232/U-238; U-235/U-238; Pu-244/Th-232; J-129/J-127. Using this method the authors have determined the age of elements from 7 to 15 billion years, the best estimate being approximately 10 billion years. This age is quite in an agreement with calculations made by other methods

  9. Fetal origin of vascular aging

    Directory of Open Access Journals (Sweden)

    Shailesh Pitale

    2011-01-01

    Full Text Available Aging is increasingly regarded as an independent risk factor for development of cardiovascular diseases such as atherosclerosis and hypertension and their complications (e.g. MI and Stroke. It is well known that vascular disease evolve over decades with progressive accumulation of cellular and extracellular materials and many inflammatory processes. Metabolic syndrome, obesity and diabetes are conventionally recognized as risk factors for development of coronary vascular disease (CVD. These conditions are known to accelerate ageing process in general and vascular ageing in particular. Adverse events during intrauterine life may programme organ growth and favour disease later in life, popularly known as, ′Barker′s Hypothesis′. The notion of fetal programming implies that during critical periods of prenatal growth, changes in the hormonal and nutritional milieu of the conceptus may alter the full expression of the fetal genome, leading to permanent effects on a range of physiological.

  10. AGING FACILITY CRITICALITY SAFETY CALCULATIONS

    Energy Technology Data Exchange (ETDEWEB)

    C.E. Sanders

    2004-09-10

    The purpose of this design calculation is to revise and update the previous criticality calculation for the Aging Facility (documented in BSC 2004a). This design calculation will also demonstrate and ensure that the storage and aging operations to be performed in the Aging Facility meet the criticality safety design criteria in the ''Project Design Criteria Document'' (Doraswamy 2004, Section 4.9.2.2), and the functional nuclear criticality safety requirement described in the ''SNF Aging System Description Document'' (BSC [Bechtel SAIC Company] 2004f, p. 3-12). The scope of this design calculation covers the systems and processes for aging commercial spent nuclear fuel (SNF) and staging Department of Energy (DOE) SNF/High-Level Waste (HLW) prior to its placement in the final waste package (WP) (BSC 2004f, p. 1-1). Aging commercial SNF is a thermal management strategy, while staging DOE SNF/HLW will make loading of WPs more efficient (note that aging DOE SNF/HLW is not needed since these wastes are not expected to exceed the thermal limits form emplacement) (BSC 2004f, p. 1-2). The description of the changes in this revised document is as follows: (1) Include DOE SNF/HLW in addition to commercial SNF per the current ''SNF Aging System Description Document'' (BSC 2004f). (2) Update the evaluation of Category 1 and 2 event sequences for the Aging Facility as identified in the ''Categorization of Event Sequences for License Application'' (BSC 2004c, Section 7). (3) Further evaluate the design and criticality controls required for a storage/aging cask, referred to as MGR Site-specific Cask (MSC), to accommodate commercial fuel outside the content specification in the Certificate of Compliance for the existing NRC-certified storage casks. In addition, evaluate the design required for the MSC that will accommodate DOE SNF/HLW. This design calculation will achieve the objective of providing the

  11. Mass media and healthy aging.

    Science.gov (United States)

    Wadsworth, Laurie A; Johnson, Christine P

    2008-01-01

    Health effects associated with media use have largely focused on children and youth with little attention paid to adults, particularly older adults. However, adults aged 60 years and older report heavy television viewing, and unique health education challenges will be faced as the technically savvy baby-boomer cohort ages. Media health effects relevant to older adults include an established causative link with adiposity and correlations to increased risk of chronic disease, reduced physical activity, and undesirable food choice behaviors. Advertising has targeted older adults as a key market segment promoting anti-aging and health related products, with potential negative body image impacts. Implications for health practitioners and research are discussed in the context of these consequences. PMID:19042578

  12. Autophagy in ageing and ageing-associated diseases

    Institute of Scientific and Technical Information of China (English)

    Li-qiang HE; Jia-hong LU; Zhen-yu YUE

    2013-01-01

    Autophagy is a cell self-digestion process via lysosomes that clears "cellular waste",including aberrantly modified proteins or protein aggregates and damaged organelles.Therefore,autophagy is considered a protein and organelle quality control mechanism that maintains normal cellular homeostasis.Dysfunctional autophagy has been observed in ageing tissues and several ageing-associated diseases.Lifespan of model organisms such as yeast,worms,flies,and mice can be extended through promoting autophagy,either by genetic manipulations such as over-expression of Sirtuin 1,or by administrations of rapamycin,resveratrol or spermidine.The evidence supports that autophagy may play an important role in delaying ageing or extending lifespan.In this review,we summarize the current knowledge about autophagy and its regulation,outline recent developments ie the genetic and pharmacological manipulations of autophagy that affects the lifespan,and discuss the role of autophagy in the ageing-related diseases.ow in Center for Neurodegenerative and Neuroimmunologic Diseases,Department of Neurology,University of Medicine and Dentistry of New Jersey-Robert Wood Johnson Medical School,Piscataway,NJ 08854,USA

  13. Evolution of aging assessment methodologies

    International Nuclear Information System (INIS)

    Under the influence of organizations like the IAEA and INPO the expectations of the regulator and plant operators alike are driving the evolution of aging assessment methodologies. The key result is that these assessments need to be executed more efficiently while supporting risk informed thinking within a living process. Some recent trends impacting aging assessments include new standards from the regulator requiring more frequent updates of aging assessments (RD-334), and broader component coverage driven by equipment reliability program demands (INPO AP-913). These trends point to the need to be able to do aging assessment more efficiently, and to manage the configuration. Some of the challenges include increasing efficiency while maintaining completeness and minimizing error, employing a systematic, well defined approach while maintaining the flexibility to apply the right level of effort to achieve desired results, and in particular, assuring that Aging Related Degradation Mechanisms (ARDMs) are sufficiently addressed. Meeting these needs creates a natural synergy with the Preventive Maintenance living program and therefore lends itself to a more integrated approach. To support this program, the SYSTMSTM software has been enhanced to accommodate for the various facets of an integrated program while meeting the needs described above. The systematic processes in SYSTMS are built with the vision of supporting risk-informed decision making as part of a larger risk-based functional tools suite. This paper intends to show how the utilities can benefit from the cost savings associated with increased assessment efficiency, and utilizing Candu Energy Inc.'s CANDU-specific knowledge-base and experience in aging assessment to get it right the first time. (author)

  14. The aging gut. Nutritional issues.

    Science.gov (United States)

    Saltzman, J R; Russell, R M

    1998-06-01

    With improvements in health care, living standards, and socioeconomic status, more adults are living to old age. As the population ages, it is increasingly important to understand the factors that affect the nutritional status and thus the health status of older adults. Many factors contribute to inadequate nutrition, including health status, financial capacities, mobility, exercise, and physiologic needs. This article considered only the potential changes in nutritional needs because of alterations in the gastrointestinal tract owing to aging. One of the most remarkable changes with aging is the frequent development of atrophic gastritis and the inability to secrete gastric acid. This process affects approximately a third of older adults in the United States and only recently was recognized to be due to infection by H. pylori in the majority of cases. The lack of gastric acid in atrophic gastritis may lead to small intestinal bacterial overgrowth and influences the absorption of a variety of micronutrients, including iron, folate, calcium, vitamin K, and vitamin B12. Lactose maldigestion is a frequent condition in older adults and is extremely common worldwide. The intolerance of dairy products leads to avoidance of these foods and likely contributes to the development of osteopenia. Overall, the small intestine and pancreas undergo astonishingly few clinically significant changes with aging. The relative preservation of overall gastrointestinal function with aging is likely due to the large reserve capacity of this multiorgan system. Further research is needed to define the precise nutritional needs for older adults because simple extrapolation of values from younger adults is now recognized to be insufficient. In addition, it is no longer acceptable to define adequate nutriture in terms of amounts of vitamins needed to maintain serum levels of a nutrient. Further RDAs must consider the functional implications of adequate nutrition. Nutrients in the elderly will

  15. [The aging of Down's Syndrome subjects].

    Science.gov (United States)

    Fromage, B; Anglade, P

    2002-01-01

    The normal ageing of Down's Syndrome subjects is comparable to that observed in individuals who have an equivalent cognitive deficit. However it is earlier and is related to the former intellectual level and life story of the person. Before 50 years, there is no significant reduction of memory. After this age short-term memory, the speed of information processing and selective attention weaken. These changes are similar to those in older non-Down's Syndrome defective adults, giving the impression of early ageing in Down's Syndrome subjects. In terms of autonomy in everyday life, it is possible to establish an average evolutionary profile. From 60 years old, deterioration is estimated at 45% of the score obtained at 40 years, affecting in particular the skills necessary for the carrying out daily tasks (washing, dressing, feeding without assistance.). We have little knowledge of the psychiatric evolution of this people because older handicapped people are a new group in society. In the three fields of cognition, autonomy and mental health, the ageing of Down's Syndrome subjects is very sensitive to their environment. Pathological ageing of the Down's Syndrome subject is associated with the dementia syndrome that, with varying degrees, combines disorders of the cognitive functions and behavior, modifying the personality. The clinical diagnosis of dementia is difficult to establish in the Down's Syndrome subject and opinions diverge, also it is important to comply with three rules: 1) to establish an individual base line and to observe, with the help of regular evaluations, a clear change in performance; this must be confirmed by similar modifications in daily conducts; 2) the decline depends not only on the resources of the subject, but also on the demands made by environment; 3) lasting deterioration of capacities must be clearly greater than that observable in normal ageing to signify dementia. As a function of actual age, the Down's Syndrome shows early signs of

  16. Capacitor ageing in electronic devices

    Directory of Open Access Journals (Sweden)

    Richard B. N. Vital

    2015-10-01

    Full Text Available The moment when an electronic component doesn’t work like requirements, previously established is a task that need to be considered since began of a system design. However, the use of different technologies, operating under several environmental conditions, makes a component choice a complex step in system design. This paper analyzes the effects that ageing phenomenon of capacitors may introduce in electronic devices operation. For this reason, reliability concepts, processes and mechanism of degradation are presented. Additionally, some mathematical models are presented to assist maintenance activities or component replacement. The presented approach compares the operability of intact and aged components.

  17. Facial aging: A clinical classification

    Directory of Open Access Journals (Sweden)

    Shiffman Melvin

    2007-01-01

    Full Text Available The purpose of this classification of facial aging is to have a simple clinical method to determine the severity of the aging process in the face. This allows a quick estimate as to the types of procedures that the patient would need to have the best results. Procedures that are presently used for facial rejuvenation include laser, chemical peels, suture lifts, fillers, modified facelift and full facelift. The physician is already using his best judgment to determine which procedure would be best for any particular patient. This classification may help to refine these decisions.

  18. Detecting and mitigating inverter aging

    International Nuclear Information System (INIS)

    Nuclear power plants use inverters to supply power to safety-related equipment, instrumentation, and controls. They convert direct current (dc) to alternating current (ac) power, thereby making low voltage ac power available even under a station blackout condition. As part of the U.S. NRC's nuclear plant aging research (NPAR) program, the operating experience of this equipment has been analyzed to determine the dominant failure modes and causes. This paper summarizes that data, and then describes methods which can be employed to detect inverter degradation prior to failure, as well as methods to minimize the failure effects. In both cases, the mitigation of inverter aging is emphasized

  19. [Age-related macular degeneration].

    Science.gov (United States)

    Budzinskaia, M V

    2014-01-01

    The review provides an update on the pathogenesis and new treatment modalities for neovascular age-related macular degeneration (AMD). The impact of polymorphism in particular genes, including complement factor H (CFH), age-related maculopathy susceptibility 2 (ARMS2/LOC387715), and serine peptidase (HTRA1), on AMD development is discussed. Clinical presentations of different forms of exudative AMD, that is classic, occult, or more often mixed choroidal neovascularization, retinal angiomatous proliferation, and choroidal polypoidal vasculopathy, are described. Particular attention is paid to the results of recent clinical trials and safety issues around the therapy. PMID:25715554

  20. Ageing adults and digital games

    DEFF Research Database (Denmark)

    Iversen, Sara Mosberg

    On the basis of Foucauldian notions of power, discipline and discourse it is here examined how ageing adults are constituted in relation to digital games within the existing research. Reviewing the available literature with a focus on justifications for research, aims and the portrayal of the...... elderly, three dominant discourses are identified. These are concerned with a generational digital divide, maintenance of health and general wellbeing as well as the ageing adults as an attractive marked. Notions of economical productivity inform most of the available work, often explicitly and at other...

  1. Physical activity, aging and cognition

    OpenAIRE

    Tazkari, Reza

    2016-01-01

    In this medium case and prospective study we showed how different kinds of exercise affect cognitive function of healthy older adults. 89 adults aged 65 to 75 years without dementia took part in the study; 37 men and 52 women. They were assigned voluntary and non-randomly – due to individually interested subjects – into one control group (CG) and into two exercise groups (EG); the CG consisted of 28 participants with an average age of 67.93 years. The EG was divided into two sub-groups doing ...

  2. Does ageing aggravate parkinsonian disability?

    OpenAIRE

    Blin, J; DuBois, B; Bonnet, A M; Vidailhet, M; Brandabur, M; Agid, Y

    1991-01-01

    The influence of age of onset of Parkinson's disease on the severity and the pattern of motor symptoms was investigated by comparing the motor scores with and without levodopa therapy in two groups of patients divided according to age of onset (early less than 50, late greater than 60 years) and matched for disease duration (n = 69 in each group, Study I). The baseline score, that is, the motor disability of patients when off levodopa, was similar in the early- and late- onset groups. In cont...

  3. Debating the Little Ice Age

    OpenAIRE

    Kelly, Morgan; Ó Gráda, Cormac

    2014-01-01

    This paper replies to commentaries by Sam White and by Ulf Büntgen and Lena Hellmann on our 'The Waning of the Little Ice Age: Climate Change in Early Modern Europe'. White and Büntgen/Hellmann seek to prove that Europe experienced the kind of sustained falls in temperature between the fifteenth and nineteenth centuries that can justify the notion of a Little Ice Age. Neither of them adequately addresses the cogency of the anecdotal or statistical evidence presented in our article, especially...

  4. Dynapenia and Aging: An Update

    OpenAIRE

    Manini, Todd M; Clark, Brian C.

    2011-01-01

    In 2008, we published an article arguing that the age-related loss of muscle strength is only partially explained by the reduction in muscle mass and that other physiologic factors explain muscle weakness in older adults (Clark BC, Manini TM. Sarcopenia =/= dynapenia. J Gerontol A Biol Sci Med Sci. 2008;63:829–834). Accordingly, we proposed that these events (strength and mass loss) be defined independently, leaving the term “sarcopenia” to be used in its original context to describe the age-...

  5. Aging exponents in self-organized criticality

    International Nuclear Information System (INIS)

    In a recent Letter [Phys. Rev. Lett. 79, 889 (1997)] we demonstrated that the avalanches in the Bak-Sneppen model display aging behavior similar to glassy systems. Numerical results for temporal correlations show a broad distribution with two distinct regimes separated by a time scale that is related to the age of the avalanche. This dynamical breaking of time-translational invariance results in a previously unrecognized critical exponent r. Here we present results for r from extensive numerical simulations of self-organized critical models in d=1 and 2. We find rd=1=0.45±0.05 and rd=2=0.23±0.05 for the Bak-Sneppen model, and our results suggest r=1/4 for the analytically tractable multitrade model in both dimensions. copyright 1997 The American Physical Society

  6. Aging exponents in self-organized criticality

    Energy Technology Data Exchange (ETDEWEB)

    Boettcher, S. [Center for Theoretical Studies of Physical Systems, Clark Atlanta University, Atlanta, Georgia 30314 (United States)]|[Center for Nonlinear Studies, MS-B258, Los Alamos National Laboratory, Los Alamos, New Mexico 87545 (United States)

    1997-12-01

    In a recent Letter [Phys. Rev. Lett. {bold 79}, 889 (1997)] we demonstrated that the avalanches in the Bak-Sneppen model display aging behavior similar to glassy systems. Numerical results for temporal correlations show a broad distribution with two distinct regimes separated by a time scale that is related to the age of the avalanche. This dynamical breaking of time-translational invariance results in a previously unrecognized critical exponent r. Here we present results for r from extensive numerical simulations of self-organized critical models in d=1 and 2. We find r{sub d=1}=0.45{plus_minus}0.05 and r{sub d=2}=0.23{plus_minus}0.05 for the Bak-Sneppen model, and our results suggest r=1/4 for the analytically tractable multitrade model in both dimensions. {copyright} {ital 1997} {ital The American Physical Society}

  7. Age-related aneuploidy through cohesion exhaustion

    OpenAIRE

    Jessberger, Rolf

    2012-01-01

    Pregnancy in older women is problematic, as oocytes are particularly prone to chromosome missegregation, and aneuploidy increases with age. Sister chromatid cohesion is weakened or lost with age, having a major impact in age-dependent aneuploidy, as discussed here.

  8. Aging changes in organs - tissue - cells

    Science.gov (United States)

    ... lose some function as you age during adulthood. Aging changes occur in all of the body's cells, ... and peripheral nerves are made of nerve tissue. AGING CHANGES Cells are the basic building blocks of ...

  9. The most pressing problem of our age

    OpenAIRE

    Kirkwood, Thomas B. L.

    2003-01-01

    The increasing proportion of elderly people in Western populations has focused attention on the ageing process. Professor Kirkwood discusses what we know about ageing and the reasons for infirmity in old age

  10. Aging changes in organs - tissue - cells

    Science.gov (United States)

    ... this page: //medlineplus.gov/ency/article/004012.htm Aging changes in organs - tissue - cells To use the ... lose some function as you age during adulthood. Aging changes occur in all of the body's cells, ...

  11. Assessment of Yeast Aging by Flow Cytometry

    Czech Academy of Sciences Publication Activity Database

    Baszczyňski, Martin; Kuřec, M.; Novák, Pavel; Brányik, Tomáš; Růžička, Marek; Drahoš, Jiří

    Bratislava : Slovak University of Technology, 2009 - (Markoš, J.), s. 317 ISBN 978-80-227-3072-3. [International Conference of Slovak Society of Chemical Engineering /36./. Tatranské Matliare (SK), 25.05.2009-29.05.2009] R&D Projects: GA ČR GA104/07/1110; GA ČR(CZ) GD104/08/H055; GA ČR GA104/06/1418 Institutional research plan: CEZ:AV0Z40720504 Keywords : yeast * aging * bud scars Subject RIV: CI - Industrial Chemistry, Chemical Engineering

  12. Visual heritage in the digital age

    CERN Document Server

    Ch'ng, Eugene; Chapman, Henry

    2013-01-01

    Heritage is everywhere, and an understanding of our past is increasingly critical to the understanding of our contemporary cultural context and place in global society. Visual Heritage in the Digital Age presents the state-of-the-art in the application of digital technologies to heritage studies, with the chapters collectively demonstrating the ways in which current developments are liberating the study, conservation and management of the past. Digital approaches to heritage have developed significantly over recent decades in terms of both the quantity and range of applications. However, rathe

  13. Functional ability at age 75: is there an impact of physical inactivity from middle age to early old age?

    DEFF Research Database (Denmark)

    Christensen, Ulla; Støvring, N; Schultz-Larsen, K;

    2006-01-01

    The aim of this study is to analyze the impact of physical inactivity from middle age to early old age on functional ability at age 75. Physical activity is measured both as cumulated activity from age 50 to 60 to 70 and at three separate points in time. Three hundred eighty-seven men and women...... smoking, sex, school education, household composition, chronic disease at baseline and functional ability at age 70 as possible confounders. There was a strong association between physical inactivity at age 70 and disability at age 75. However, the analyses showed no effect of cumulated physical...... inactivity from age 50 to 60 to 70 on disability at age 75 when adjusting for functional ability at age 70. Physical inactivity is a risk factor for disability among old people. Thus, old people should be encouraged to take up and maintain physical training throughout the aging process....

  14. PPARγ and Stress: Implications for Aging

    OpenAIRE

    Ulrich-Lai, Yvonne M.; Ryan, Karen K.

    2012-01-01

    Complex interactions link psychological stress and aging - stress generally promotes aging processes, and conversely, aging can contribute to stress dysregulation. Stress and aging have remarkably similar effects on brain. Both induce neuroinflammation and alter neuronal metabolism and activity, which to varying extents are causally-linked to the development of stress and aging pathology. As such, induction of one or more of these brain disturbances by either stress or aging could predispose ...

  15. Age trajectories of stroke case fatality

    DEFF Research Database (Denmark)

    Olsen, Tom Skyhøj; Andersen, Zorana Jovanovic; Andersen, Klaus Kaae

    2011-01-01

    Mortality rates level off at older ages. Age trajectories of stroke case-fatality rates were studied with the aim of investigating prevalence of this phenomenon, specifically in case-fatality rates at older ages.......Mortality rates level off at older ages. Age trajectories of stroke case-fatality rates were studied with the aim of investigating prevalence of this phenomenon, specifically in case-fatality rates at older ages....

  16. Age Changes in Subjective Work Ability

    OpenAIRE

    Solem, Per Erik

    2009-01-01

    This article explores the influence of psychosocial work environment on age-related subjective changes in work ability and discusses differences between work ability and job performance. The results show age and physical health to be strong predictors of subjective decline in work ability. The age effect is independent of age-associated declining health. It is not clear what it is about age that produces the subjective decline in work ability. While primary age changes may produce decline, st...

  17. Skeletal Aging and Osteoporosis Biomechanics and Mechanobiology

    CERN Document Server

    2013-01-01

    The focus of this book is on mechanical aspects of skeletal fragility related to aging and osteoporosis. Topics include: Age-related changes in trabecular structure and strength; age-related changes in cortical material properties; age-related changes in whole-bone structure; predicting bone strength and fracture risk using image-based methods and finite element analysis; animal models of osteoporosis and aging; age-related changes in skeletal mechano responsiveness; exercise and physical interventions for osteoporosis.

  18. Successful Aging: Multiple Trajectories and Population Heterogeneity

    OpenAIRE

    2014-01-01

    Following Rowe and Kahn¡¯s successful aging model, this study identified successful aging as a distinctive aging trajectory and examined gender differences in the aging process. Using the Health and Retirement Study data (2000-2008), this study applied group-based trajectory analysis to identify multiple aging trajectories in a sample of older Americans aged 65 and over (N=9,226). Six dimensions were analyzed in the multi-trajectory model: chronic disease, physical functional limitation, disa...

  19. How to estimate dental age in paleodontology?

    Directory of Open Access Journals (Sweden)

    Vedran Šebečić

    2010-06-01

    Full Text Available Nowadays there are many methods available for dental age estimation: morphological, radiological, biochemical. Some methods require sample sectioning while other non-destructive methods are more appropriate for use in paleodontology. Children’s dental age assessment is based on phases in growth and development of the deciduous and permanent dentition, while age assessment in the adult dentition is based upon changes in the structure of hard dental tissue caused by aging. Dental age calculating software enables automated age calculations.

  20. Telework and the Information Age.

    Science.gov (United States)

    Stanworth, Celia

    1998-01-01

    Review of Information Age literature found not enough evidence that information industries will reenergize economies or provide high-quality jobs. Virtual organizations are hard to identify. Women do the bulk of low-skill, low-paying telework jobs, reinforcing sex roles and class divisions. Remote workers are often vulnerable and cut off from…