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Sample records for aged prevalence covariates

  1. Age-related changes in brain structural covariance networks

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    Xinwei eLi

    2013-03-01

    Full Text Available Previous neuroimaging studies have suggested that cerebral changes over normal aging are not simply characterized by regional alterations, but rather by the reorganization of cortical connectivity patterns. The investigation of structural covariance networks (SCNs using voxel-based morphometry is an advanced approach to examining the pattern of covariance in gray matter volumes among different regions of the human cortex. To date, how the organization of critical SCNs change during normal aging remains largely unknown. In this study, we used an SCN mapping approach to investigate eight large-scale networks in 240 healthy participants aged 18–89 years. These participants were subdivided into young (18–23 years, middle aged (30–58 years, and older (61–89 years subjects. Eight seed regions were chosen from widely reported functional intrinsic connectivity networks. The voxels showing significant positive associations with these seed regions were used to describe the topological organization of an SCN. All of these networks exhibited non-linear patterns in their spatial extent that were associated with normal aging. These networks, except the primary motor network, had a distributed topology in young participants, a sharply localized topology in middle aged participants, and were relatively stable in older participants. The structural covariance derived using the primary motor cortex was limited to the ipsilateral motor regions in the young and older participants, but included contralateral homologous regions in the middle aged participants. In addition, there were significant between-group differences in the structural networks associated with language-related speech and semantics processing, executive control, and the default-mode network. Taken together, the results of this study demonstrate age-related changes in the topological organization of SCNs, and provide insights into normal aging of the human brain.

  2. Treated versus non-treated subjects with depression from a 30-year cohort study: prevalence and clinical covariates.

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    Hengartner, Michael P; Angst, Felix; Ajdacic-Gross, Vladeta; Rössler, Wulf; Angst, Jules

    2016-03-01

    The aim of this study was to determine prevalence rates of several components of depression (unipolar and bipolar major, minor, recurrent brief depression, and dysthymia) and to identify covariates of treatment. We analysed a representative population-based, long-term prospective cohort study from age 20 to 50. Across the seven semi-structured interviews, generalized estimating equations examined the associations between diagnoses and treatment status during the course. The results show that the mean annual treatment rate across 30 years in persons with MDE was 39.2%. The weighted treatment prevalence for any depressive disorder was 23.4% (15.7% for MDE, 4.3% for minor depressive disorders and 3.4% for non-diagnosed subjects). Persons were more likely to seek treatment as they grew older. Women with MDE had triple the treatment prevalence of men (23.8 vs. 7.4%). Variables of distress/suffering under depression (OR 1.36-1.52) and the number of diagnostic depressive symptoms (OR 1.47) were statistically significant predictors of treatment, as were episode duration (OR 2.21) and various variables assessing impairment due to depression (OR 4.65-8.02). In conclusion, only a minority of persons with depressive disorders seek professional treatment in the year of disorder onset. Women and subjects suffering from high levels of depressive symptoms, frequent episodes, long episode duration and consecutive high distress and impairment were more likely to seek treatment. PMID:26499773

  3. Skin pentosidine and telomere length do not covary with age in a long-lived seabird.

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    Rattiste, Kalev; Klandorf, Hillar; Urvik, Janek; Sepp, Tuul; Asghar, Muhammad; Hasselquist, Dennis; Cooey, Crissa; Hõrak, Peeter

    2015-08-01

    The questions about why and how senescence occurs in the wild are among the most pertinent ones in evolutionary ecology. Telomere length is a commonly used marker for aging, while other biomarkers of aging have received considerably less attention. Here we studied how another potent indicator of aging-skin pentosidine concentration-relates to age and blood telomere length in a long-lived seabird with well-documented reproductive senescence. We found no associations between telomere length, skin pentosidine and chronological age in male common gulls (Larus canus), aging from 2 to 30 years. However, the variance in telomere length was 4.6 times higher among the birds older than 13 years, which hints at relaxed selection on telomere length among the birds that have passed their prime age of reproduction. These results suggest that physiological and chronological ages may be largely uncoupled in our study system. Furthermore, our findings do not support a hypothesis about the presence of a common physiological factor (e.g., such as oxidative stress) that would cause covariation between two independent markers of aging. PMID:25726322

  4. Skin pentosidine and telomere length do not covary with age in a long-lived seabird.

    Science.gov (United States)

    Rattiste, Kalev; Klandorf, Hillar; Urvik, Janek; Sepp, Tuul; Asghar, Muhammad; Hasselquist, Dennis; Cooey, Crissa; Hõrak, Peeter

    2015-08-01

    The questions about why and how senescence occurs in the wild are among the most pertinent ones in evolutionary ecology. Telomere length is a commonly used marker for aging, while other biomarkers of aging have received considerably less attention. Here we studied how another potent indicator of aging-skin pentosidine concentration-relates to age and blood telomere length in a long-lived seabird with well-documented reproductive senescence. We found no associations between telomere length, skin pentosidine and chronological age in male common gulls (Larus canus), aging from 2 to 30 years. However, the variance in telomere length was 4.6 times higher among the birds older than 13 years, which hints at relaxed selection on telomere length among the birds that have passed their prime age of reproduction. These results suggest that physiological and chronological ages may be largely uncoupled in our study system. Furthermore, our findings do not support a hypothesis about the presence of a common physiological factor (e.g., such as oxidative stress) that would cause covariation between two independent markers of aging.

  5. Prevalence of eating disorders in middle-aged women

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    Mangweth-Matzek, Barbara; Hoek, Hans W.; Rupp, Claudia I.; Lackner-Seifert, Kerstin; Frey, Nadja; Whitworth, Alexandra B.; Pope, Harrison G.; Kinzl, Johann

    2014-01-01

    Objective: Little is known about the prevalence and correlates of eating disorders (ED) in middle-aged women. Method: We mailed anonymous questionnaires to 1,500 Austrian women aged 40-60 years, assessing ED (defined by DSM-IV), subthreshold ED, body image, and quality of life. We broadly defined "s

  6. Prevalence, incidence, and age at diagnosis in Marfan Syndrome

    DEFF Research Database (Denmark)

    Groth, Kristian A; Hove, Hanne; Kyhl, Kasper;

    2015-01-01

    have reported a wide range of prevalence and incidence. Our aim was to study prevalence, incidence, and age at diagnosis in patients with Marfan syndrome. Method: Using unique Danish patient-registries, we identified all possible Marfan syndrome patients recorded by the Danish healthcare system (1977....... The annual median incidence was 0.19/100,000 (range: 0.0-0.7) which increased significantly with an incidence rate ratio of 1.03 (95 % CI: 1.02-1.04, p age at diagnose of 19.0 years (range: 0.0-74). The age at diagnosis increased during the study period, uninfluenced by the changes...... and physicians caring for adults....

  7. Simulation studies of age-specific lifetime major depression prevalence

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    Gordon-Brown Lee

    2010-10-01

    Full Text Available Abstract Background The lifetime prevalence (LTP of Major Depressive Disorder (MDD is the proportion of a population having met criteria for MDD during their life up to the time of assessment. Expectation holds that LTP should increase with age, but this has not usually been observed. Instead, LTP typically increases in the teenage years and twenties, stabilizes in adulthood and then begins to decline in middle age. Proposed explanations for this pattern include: a cohort effect (increasing incidence in more recent birth cohorts, recall failure and/or differential mortality. Declining age-specific incidence may also play a role. Methods We used a simulation model to explore patterns of incidence, recall and mortality in relation to the observed pattern of LTP. Lifetime prevalence estimates from the 2002 Canadian Community Health Survey, Mental Health and Wellbeing (CCHS 1.2 were used for model validation and calibration. Results Incidence rates predicting realistic values for LTP in the 15-24 year age group (where mortality is unlikely to substantially influence prevalence lead to excessive LTP later in life, given reasonable assumptions about mortality and recall failure. This suggests that (in the absence of cohort effects incidence rates decline with age. Differential mortality may make a contribution to the prevalence pattern, but only in older age categories. Cohort effects can explain the observed pattern, but only if recent birth cohorts have a much higher (approximately 10-fold greater risk and if incidence has increased with successive birth cohorts over the past 60-70 years. Conclusions The pattern of lifetime prevalence observed in cross-sectional epidemiologic studies seems most plausibly explained by incidence that declines with age and where some respondents fail to recall past episodes. A cohort effect is not a necessary interpretation of the observed pattern of age-specific lifetime prevalence.

  8. Dynapenic Obesity and Prevalence of Type 2 Diabetes in Middle-Aged Japanese Men

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    Ryoko Kawakami

    2015-11-01

    Full Text Available Background: The independent and combined associations of muscle strength and obesity on the prevalence of type 2 diabetes in Japanese men remain unclear. Methods: Hand grip strength was cross-sectionally evaluated between 2011 and 2013 to assess muscle strength in 5039 male workers aged 40 to 64 years. Weight and height were measured, and overweight/obesity was defined as a body mass index ≥25 kg/m2. The prevalence of type 2 diabetes, defined as fasting plasma glucose ≥126 mg/dL and/or hemoglobin A1c ≥6.5% and/or self-reported physician-diagnosed diabetes, was evaluated. Odds ratios (OR and 95% confidence intervals (95% CI for the prevalence of type 2 diabetes were obtained using a logistic regression model. Results: In total, 611 participants had type 2 diabetes, and 1763 participants were overweight/obese. After adjustment for covariates, we found an inverse association between muscle strength and the prevalence of type 2 diabetes (P for trend <0.01. In addition, when the analyses were stratified by obesity status, the multivariable-adjusted OR per 2-standard-deviation increase in muscle strength was 0.64 (95% CI, 0.49–0.83 in the overweight/obese group, compared to a weaker relationship in the normal-weight group (OR 0.79 per 2-standard-deviation increase; 95% CI, 0.60–1.06. Conclusions: Dynapenia, an age-related decrease in muscle strength, is associated with increased prevalence of type 2 diabetes, and this relationship is stronger in overweight/obese middle-aged Japanese men than in normal-weight men.

  9. An age structured model for obesity prevalence dynamics in populations

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    Gilberto González Parra

    2010-08-01

    Full Text Available Objective. Modeling the correlation of the development of obesity in a population with age and time and predict the dynamics of the correlation of the development of obesity in a population with age and time under different scenarios in Valencia (Spain. Materials and methods. An age structured mathematical model is used to describe the future dynamics of obesity prevalence for different ages in human population with excess weight. Simulation of the model with parameters estimated using the Health Survey of the Region of Valencia 2000 (4.319 interviews and Health Survey of the Region of Valencia 2005 (4.012 interviews. The model considers only overweight and obese populations since these subpopulations are the most relevant on obesity health concern. Results. The model allows predicting and studying the prevalence of obesity for each age. Results showed an increasing trend of obesity in the following years in well accordance with the trend observed in several countries. Conclusions. Based on the numerical simulations it is possible to conclude that the age structured mathematical model is suitable to forecast the obesity epidemic in each age group in different countries. Additionally, this type of models may be applied to study other characteristics of other populations such animal populations.

  10. Prevalence of Successful Aging in the Elderly in Western Mexico

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    Elva Dolores Arias-Merino

    2012-01-01

    Full Text Available Objectives. The aim of this paper is to estimate the prevalence of successful aging in the elderly in Western Mexico and to analyze its variability by age, sex, education, marital status, and pension. Methods. This study employs data from the Health, Wellbeing, and Aging Study (SABE in Jalisco and Colima, Mexico. Successful aging was operationalized in accordance with no important disease, no disability, physical functioning, cognitive functioning, and being actively. There were a total of 3116 elderly. Results. 12.6% of older adults were “successful” aging. The old-old is a lower proportion of successful aging people; it ranges from 18.9% among people aged 60–69 years to 3.9% in the 80–89 years and up to 1% in people 90 and older. There were also differences according to sex (P=.000, with a higher proportion of successful aging men (18.4% compared with 9.2% of women. There were differences in educational level (P=.000; those higher with education were found to be more successful aging, and also there were differences in marital status for married people (P=.000. Discussion. A small number of older adults meet the criteria definition of successful aging, suggesting the need to analyze in depth the concept and the indicators.

  11. COMPONENTS OF (COVARIANCE FOR AGE AT FIRST AND SECOND CALVING OF NELLORE FEMALES RAISED IN SOUTHERN BRAZIL

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    Dionéia Magda Everling

    2015-10-01

    Full Text Available The objective of this study was to estimate the heritability, genetic correlation and estimated breeding values for age at first (AFC and second calving (ASC for Nellore females raised in Southern Brazil. The (covariance and estimated breeding values were obtained using Bayesian inference in a bivariate analysis, adopting an animal model. The average ages were 49.30 and 69.85 months, and the heritabilities were 0.25 and 0.26, respectively for AFC and ASC. The genetic correlation between AFC and ASC was 0.88. The correlation between the classifications of sires according to their estimated breeding values was 0.93. The heritability estimates for AFC and ASC suggest the possibility of obtaining genetic gain by selection. The correlation between these traits close to one indicates that they are controlled by virtually the same genes and when selected for one will advance correlated gain for the other.

  12. The Prevalence of Overweight and Obesity Among Aging Female Inmates.

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    Leigey, Margaret E; Johnston, Mary E

    2015-07-01

    The purpose of this study was to examine the prevalence of overweight and obesity in a sample of older female inmates (N = 458). Results indicate that 34% of older female inmates were overweight and 36% were obese; similar percentages were noted for the general population. Race and age were found to be significantly associated with the body mass index categories of healthy weight and obese. White inmates were significantly more likely to be of a healthy weight and significantly less likely to be obese than Black inmates. Age was positively associated with healthy weight and negatively associated with obesity. These two variables remained significant even after they were introduced into logistic regression models predicting healthy weight and obesity. Findings indicate the need for programming to improve the health of this population.

  13. Covariance fields

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    Balov, Nikolay H.

    2008-01-01

    We introduce and study covariance fields of distributions on a Riemannian manifold. At each point on the manifold, covariance is defined to be a symmetric and positive definite (2,0)-tensor. Its product with the metric tensor specifies a linear operator on the respected tangent space. Collectively, these operators form a covariance operator field. We show that, in most circumstances, covariance fields are continuous. We also solve the inverse problem: recovering distribution from a covariance...

  14. Covariation of deep Southern Ocean oxygenation and atmospheric CO2 through the last ice age.

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    Jaccard, Samuel L; Galbraith, Eric D; Martínez-García, Alfredo; Anderson, Robert F

    2016-02-11

    No single mechanism can account for the full amplitude of past atmospheric carbon dioxide (CO2) concentration variability over glacial-interglacial cycles. A build-up of carbon in the deep ocean has been shown to have occurred during the Last Glacial Maximum. However, the mechanisms responsible for the release of the deeply sequestered carbon to the atmosphere at deglaciation, and the relative importance of deep ocean sequestration in regulating millennial-timescale variations in atmospheric CO2 concentration before the Last Glacial Maximum, have remained unclear. Here we present sedimentary redox-sensitive trace-metal records from the Antarctic Zone of the Southern Ocean that provide a reconstruction of transient changes in deep ocean oxygenation and, by inference, respired carbon storage throughout the last glacial cycle. Our data suggest that respired carbon was removed from the abyssal Southern Ocean during the Northern Hemisphere cold phases of the deglaciation, when atmospheric CO2 concentration increased rapidly, reflecting--at least in part--a combination of dwindling iron fertilization by dust and enhanced deep ocean ventilation. Furthermore, our records show that the observed covariation between atmospheric CO2 concentration and abyssal Southern Ocean oxygenation was maintained throughout most of the past 80,000 years. This suggests that on millennial timescales deep ocean circulation and iron fertilization in the Southern Ocean played a consistent role in modifying atmospheric CO2 concentration.

  15. Covariation of deep Southern Ocean oxygenation and atmospheric CO2 through the last ice age.

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    Jaccard, Samuel L; Galbraith, Eric D; Martínez-García, Alfredo; Anderson, Robert F

    2016-02-11

    No single mechanism can account for the full amplitude of past atmospheric carbon dioxide (CO2) concentration variability over glacial-interglacial cycles. A build-up of carbon in the deep ocean has been shown to have occurred during the Last Glacial Maximum. However, the mechanisms responsible for the release of the deeply sequestered carbon to the atmosphere at deglaciation, and the relative importance of deep ocean sequestration in regulating millennial-timescale variations in atmospheric CO2 concentration before the Last Glacial Maximum, have remained unclear. Here we present sedimentary redox-sensitive trace-metal records from the Antarctic Zone of the Southern Ocean that provide a reconstruction of transient changes in deep ocean oxygenation and, by inference, respired carbon storage throughout the last glacial cycle. Our data suggest that respired carbon was removed from the abyssal Southern Ocean during the Northern Hemisphere cold phases of the deglaciation, when atmospheric CO2 concentration increased rapidly, reflecting--at least in part--a combination of dwindling iron fertilization by dust and enhanced deep ocean ventilation. Furthermore, our records show that the observed covariation between atmospheric CO2 concentration and abyssal Southern Ocean oxygenation was maintained throughout most of the past 80,000 years. This suggests that on millennial timescales deep ocean circulation and iron fertilization in the Southern Ocean played a consistent role in modifying atmospheric CO2 concentration. PMID:26840491

  16. Prevalence of Depression among Undergraduate Students: Gender and Age Differences

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    Leila Ghaedi

    2014-06-01

    Full Text Available Depressive disorders are the most typical disease affecting many different factors of humanity. University students may be at increased risk of depression owing to the pressure and stress they encounter. Therefore, the purpose of this study is comparing the level of depression among male and female athletes and non-athletes undergraduate student of private university in Esfahan, Iran. The participants in this research are composed of 400 male and female athletes as well as no-athletes Iranian undergraduate students. The Beck depression test (BDI was employed to measure the degree of depression. T-test was used to evaluate the distinction between athletes and non-athletes at P≤0.05. The ANOVA was conducted to examine whether there was a relationship between level of depression among non-athletes and athletes. The result showed that the prevalence rate of depression among non-athlete male undergraduate students is significantly higher than that of athlete male students. The results also presented that level of depression among female students is much more frequent compared to males. This can be due to the fatigue and lack of energy that are more frequent among female in comparison to the male students. Physical activity was negatively related to the level of depression by severity among male and female undergraduate students. However, there is no distinct relationship between physical activity and level of depression according to the age of athlete and nonathlete male and female undergraduate students. This study has essential implications for clinical psychology due to the relationship between physical activity and prevalence of depression.

  17. Reduced blood parasite prevalence with age in the Seychelles Warbler: selecive mortality or suppression of infection?

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    Van Oers, K.; Richardson, D.; Saether, S.A.; Komdeur, J.

    2010-01-01

    Avian malaria can affect survival and reproduction of their hosts. Two patterns commonly observed in birds are that females have a higher prevalence of malaria than do males and that prevalence decreases with age. The mechanisms behind these patterns remain unclear. However, most studies on blood pa

  18. Reduced blood parasite prevalence with age in the Seychelles Warbler : selective mortality or suppression of infection?

    NARCIS (Netherlands)

    van Oers, Kees; Richardson, David S.; Saether, Stein A.; Komdeur, Jan; Guglielmo, C.G.

    2010-01-01

    Avian malaria can affect survival and reproduction of their hosts. Two patterns commonly observed in birds are that females have a higher prevalence of malaria than do males and that prevalence decreases with age. The mechanisms behind these patterns remain unclear. However, most studies on blood pa

  19. Behavioral Risk Factor Surveillance System (BRFSS) Age-Adjusted Prevalence Data (2011 to present)

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    U.S. Department of Health & Human Services — 2011 to present. BRFSS combined land line and cell phone age-adjusted prevalence data. The BRFSS is a continuous, state-based surveillance system that collects...

  20. Comparison of age-specific cataract prevalence in two population-based surveys 6 years apart

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    Rochtchina Elena

    2006-04-01

    Full Text Available Abstract Background In this study, we aimed to compare age-specific cortical, nuclear and posterior subcapsular (PSC cataract prevalence in two surveys 6 years apart. Methods The Blue Mountains Eye Study examined 3654 participants (82.4% of those eligible in cross-section I (1992–4 and 3509 participants (75.1% of survivors and 85.2% of newly eligible in cross-section II (1997–2000, 66.5% overlap with cross-section I. Cataract was assessed from lens photographs following the Wisconsin Cataract Grading System. Cortical cataract was defined if cortical opacity comprised ≥ 5% of lens area. Nuclear cataract was defined if nuclear opacity ≥ Wisconsin standard 4. PSC was defined if any present. Any cataract was defined to include persons who had previous cataract surgery. Weighted kappa for inter-grader reliability was 0.82, 0.55 and 0.82 for cortical, nuclear and PSC cataract, respectively. We assessed age-specific prevalence using an interval of 5 years, so that participants within each age group were independent between the two surveys. Results Age and gender distributions were similar between the two populations. The age-specific prevalence of cortical (23.8% in 1st, 23.7% in 2nd and PSC cataract (6.3%, 6.0% was similar. The prevalence of nuclear cataract increased slightly from 18.7% to 23.9%. After age standardization, the similar prevalence of cortical (23.8%, 23.5% and PSC cataract (6.3%, 5.9%, and the increased prevalence of nuclear cataract (18.7%, 24.2% remained. Conclusion In two surveys of two population-based samples with similar age and gender distributions, we found a relatively stable cortical and PSC cataract prevalence over a 6-year period. The increased prevalence of nuclear cataract deserves further study.

  1. Racial/Ethnic Differences in the Prevalence of Depressive Symptoms Among Middle-Aged Women: The Study of Women’s Health Across the Nation (SWAN)

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    Bromberger, Joyce T.; Harlow, Sioban; Avis, Nancy; Kravitz, Howard M.; Cordal, Adriana

    2004-01-01

    Objectives. We examined racial/ethnic differences in significant depressive symptoms among middle-aged women before and after adjustment for socioeconomic, health-related, and psychosocial characteristics. Methods. Racial/ethnic differences in unadjusted and adjusted prevalence of significant depressive symptoms (score ≥ 16 on the Center for Epidemiologic Studies Depression [CES-D] Scale) were assessed with univariate and multiple logistic regressions. Results. Twenty-four percent of the sample had a CES-D score of 16 or higher. Unadjusted prevalence varied by race/ethnicity (P < .0001). After adjustment for covariates, racial/ethnic differences overall were no longer significant. Conclusions. Hispanic and African American women had the highest odds, and Chinese and Japanese women had the lowest odds, for a CES-D score of 16 or higher. This variation is in part because of health-related and psychosocial factors that are linked to socioeconomic status. PMID:15284047

  2. Association between adolescent idiopathic scoliosis prevalence and age at menarche in different geographic latitudes

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    Mihas Constantinos

    2006-05-01

    Full Text Available Abstract Background Age at menarche is considered a reliable prognostic factor for idiopathic scoliosis and varies in different geographic latitudes. Adolescent idiopathic scoliosis prevalence has also been reported to be different in various latitudes and demonstrates higher values in northern countries. A study on epidemiological reports from the literature was conducted to investigate a possible association between prevalence of adolescent idiopathic scoliosis and age at menarche among normal girls in various geographic latitudes. An attempt is also made to implicate a possible role of melatonin in the above association. Material-methods 20 peer-reviewed published papers reporting adolescent idiopathic scoliosis prevalence and 33 peer-reviewed papers reporting age at menarche in normal girls from most geographic areas of the northern hemisphere were retrieved from the literature. The geographic latitude of each centre where a particular study was originated was documented. The statistical analysis included regression of the adolescent idiopathic scoliosis prevalence and age at menarche by latitude. Results The regression of prevalence of adolescent idiopathic scoliosis and age at menarche by latitude is statistically significant (p Conclusion Late age at menarche is parallel with higher prevalence of adolescent idiopathic scoliosis. Pubarche appears later in girls that live in northern latitudes and thus prolongs the period of spine vulnerability while other pre-existing or aetiological factors are contributing to the development of adolescent idiopathic scoliosis. A possible role of geography in the pathogenesis of idiopathic scoliosis is discussed, as it appears that latitude which differentiates the sunlight influences melatonin secretion and modifies age at menarche, which is associated to the prevalence of idiopathic scoliosis.

  3. Prevalence and Incidence of Myocardial Infarction and Cerebrovascular Accident in Ageing Persons with Intellectual Disability

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    Jansen, J.; Rozeboom, W.; Penning, C.; Evenhuis, H. M.

    2013-01-01

    Background: Epidemiological information on age-related cardiovascular disease in people with intellectual disability (ID) is scarce and inconclusive. We compared prevalence and incidence of cerebrovascular accident and myocardial infarction over age 50 in a residential population with ID to that in a general practice population. Method: Lifetime…

  4. Prevalence of Parasomnia in School aged Children in Tehran

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    Morteza Naserbakht

    2011-06-01

    Full Text Available "nObjectives: Parasomnias can create sleep disruption; in this article we assessed parasomnias in school-aged children in Tehran. "nMethods: In spring 2005, a total of 6000 sleep questionnaires were distributed to school-aged children in 5 districts of Tehran (Iran. A modified Pediatrics sleep questionnaire with 34 questions was used. "nResults: Parasomnias varied from 0.5% to 5.7% among the subjects as follows: 2.7% sleep talking, 0.5% sleepwalking, 5.7% bruxism, 2.3% enuresis, and nightmare 4%. A group of children showed parasomnias occasionally- this was 13.1% for sleep talking, 1.4% for sleepwalking, 10.6% for bruxism, 3.1% for enuresis and 18.4% for nightmares. "nConclusion: A high proportion of children starting school suffer from sleep problems. In many cases this is a temporary, developmentally related phenomenon, but in 6% of the children the disorder is more serious and may be connected with various stress factors and further behavioral disturbances.

  5. The prevalence of lacunar infarct decreases with aging in the elderly: a case-controlled analysis

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    Cai Z

    2016-05-01

    Full Text Available Zhiyou Cai,1 Wenbo He,1 Chuan-yong Peng,2 Jin Zhou,2 Qi-lan Xu,2 Zong-shan Wu2 1Department of Neurology, Renmin Hospital, Hubei University of Medicine, Shiyan Renmin Hospital, Shiyan, Hubei Province, 2The Examination Center of Magnetic Resonance Imaging, the Lu’an Affiliated Hospital of Anhui Medical University, Lu’an People’s Hospital, Lu’an, Anhui Province, People’s Republic of China Background and purpose: Lacunar infarct (LI is well known as a heterogeneous primary disorder of cerebral small vessel. Compelling results have demonstrated that age is a risk factor to the prevalence of LI. However, the relationship between age and the prevalence of LI remains obscure. It is essential to note the relationship between age and the prevalence of LI through more clinical data. Methods: A total of 3,500 patients were included in the case-controlled study. All data were collected from the Examination Center of Magnetic Resonance Imaging, Lu’an People’s Hospital from January 2014 to December 2015. A primary discharge diagnosis of LI was done, and all subjects were evaluated as retrospective data. The relationship between the risk factors and the prevalence of diabetes and the relationship between age and the prevalence of diabetes was analyzed. A chi-square test was used to analyze the associations between different variables. A one-way analysis of variance was used to test the equality of three or more means at one time by using variances. Statistical significance was defined as a P-value of <0.05. Results: The one-way analysis of variance demonstrated that the prevalence of LI increased with age before 60 years and decreased with age after 69 years. The same results were found in both the male and the female subjects. These results showed that the age-related risk factors (hypertension, diabetes, cerebral infarct, cardiovascular diseases, smoking, and drinking have no relationship with the prevalence of LI on the basis of age. There is

  6. Analysing cross-sectional data with time-dependent covariates: the case of age at first birth in South Africa.

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    Amoateng, Acheampong Yaw; Kalule-Sabiti, I; Ditlopo, Prudence

    2003-07-01

    Analysing time-dependent independent variables requires the use of process-oriented statistical models. Yet social scientists--especially those in poor countries--have often had to use data collected at a single point in time, making their task difficult. Making several assumptions about the covariates, the present study uses survival analysis and other statistical techniques to analyse the 1996 South African population census data and examine the effects of selected independent variables on the timing of parenthood in the country. It was found that the onset of parenthood occurs late in South Africa compared with the pattern in most other African societies. While education plays a role in the postponement of parenthood within racial groups, it fails to explain the differences between African and Coloured women on the one hand, and White and Asian women on the other hand, a finding that suggests the existence of two regimes of family formation in South African society. PMID:12887218

  7. Prevalence and risk factors of atrial fibrillation in preterminal inpatients aged 60 years and over

    Institute of Scientific and Technical Information of China (English)

    YANG Jie-fu; LIU Bing; LIU Dong-ge; LUO Yao; FANG Fang

    2008-01-01

    Background Atrial fibrillation is a common arrhythmia and a major risk factor for ischaemic stroke. We investigated the prevalence of atrial fibrillation and its relation to age, gender and underlying heart disease in patients aged 60 years and over who died during hospitalization.Methods Between 1955 and 2005, 1519 autopsies of in-hospital deaths in Beijing Hospital were performed. Among them, 540 cases met criteria of age ≥60 years and full clinical history including electrocardiogram, echocardiogram, myocardial perfusion images and detailed cardiac pathology records from autopsy.Results Atrial fibrillation occurred in 193 of 540 patients and prevalence increased with age (10.5% in patients younger than 60 years, 39.6% (80-89 years) and 54.8% (≥90 years)) being higher in patients with underlying heart disease than without heart disease (P<0.0001). Coronary artery disease (CAD), congestive heart failure, cardiac valve dysfunction and chronic renal failure were associated with a higher prevalence of atrial fibrillation (P<0.001). CAD with anterior myocardial infarction or left anterior descending artery disease was also associated with an increased prevalence of atrial fibrillation (P <0.05). Following autopsy, clinical misdiagnosis of CAD increased with age and missed clinical diagnosis of CAD decreased with age. Multivariate Logistic regression analysis revealed independent predictors of atrial fibrillation: age (OR=1.335, 95% Cl: 1.114-1.600, P<0.0001), underlying heart disease (OR=2.019, 95% CI: 1.244-3.278, P <0.005), chronic heart failure (OR=1.873, 95% CI: 1.272-2.757, P <0.005), mitral regurgitation (OR=2.163, 95% Cl: 1.093-4.278, P<0.05) and mitral stenosis (OR=33.575, 95% CI: 2.852-395.357, P<0.05). Conclusions A high prevalence of atrial fibrillation was found in Chinese patients

  8. Prevalence of hypospadias in Italy according to severity, gestational age and birthweight: an epidemiological study

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    Magnani Cinzia

    2009-06-01

    Full Text Available Abstract Background Hypospadias is a congenital displacement of the urethral meatus in male newborns, being either an isolated defect at birth or a sign of sexual development disorders. The aim of this study was to assess the prevalence rate of hypospadias in different Districts of Italy, in order to make a comparison with other countries all over the world. Methods We reviewed all the newborns file records (years 2001–2004 in 15 Italian Hospitals. Results We found an overall hypospadias prevalence rate of 3.066 ± 0.99 per 1000 live births (82.48% mild hypospadias, 17.52% moderate-severe. In newborns Small for Gestational Age (birthweight th percentile of any gestational age the prevalence rate of hypospadias was 6.25 per 1000 live births. Performing multivariate logistic regression analysis for different degrees of hypospadias according to severity, being born SGA remained the only risk factor for moderate-severe hypospadias (p = 0.00898 but not for mild forms (p > 0.1. Conclusion In our sample the prevalence of hypospadias results as high as reported in previous European and American studies (3–4 per 1000 live births. Pathogenesis of isolated hypospadias is multifactorial (genetic, endocrine and environmental factors: however, the prevalence rate of hypospadias is higher in infants born small for gestational age than in newborns with normal birth weight.

  9. Prevalence of metabolic syndrome in adolescents aged 10-18 years in Jammu, J and K

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    Narinder Singh

    2013-01-01

    Full Text Available Objective: To estimate the prevalence of metabolic syndrome among adolescents attending school in the Jammu region, India. Materials and Methods: This is a cross-sectional study conducted between November 2009 and December 2010, among a total of 1160 school-going adolescents of both sexes aged 10-18 years. Relevant metabolic and anthropometric variables were analyzed and criteria suggested by National Cholesterol Education Program Adult Treatment Panel Third (NCEP-ATP III modified for age was used to define metabolic syndrome. Results: The overall prevalence of metabolic syndrome was 2.6%. Prevalence of metabolic syndrome was higher in males (3.84% than in females (1.6% and slightly higher in urban area (2.80% than in rural area (2.52%, whereas prevalence of metabolic syndrome among centrally obese subjects was as high as 33.33%. High density lipoprotein cholesterol was the most common and high blood pressure was the least common constituent of metabolic syndrome. Metabolic syndrome was most prevalent in 16-18 years age group (4.79%. Conclusion : This study demonstrates that metabolic syndrome phenotype exists in substantial number (up to 3% of adolescent population in the Jammu region, India, and particularly 33% of obese adolescents are at risk to develop metabolic syndrome. These findings pose a serious threat to the current and future health of these young people.

  10. The AGES-Reykjavík Study: The Prevalence of Amnestic MCI in an Elderly Population

    OpenAIRE

    Vin Þorsteinsdóttir 1973

    2009-01-01

    Amnestic MCI (aMCI) has been consistently singled out as an important risk factor for Alzheimer´s dementia but few studies have investigated the multidomain amnestic subtype of MCI. The purpose of this study was first to estimate the prevalence of the two amnestic MCI subtypes, single domain and multidomain and second, to examine the associations of age, gender and education level with singleand multidomain amnestic MCI. A community sample of 2135 non-demented individuals aged ...

  11. Prevalence of weight excess according to age group in students from Campinas, SP, Brazil

    OpenAIRE

    Silvia Diez Castilho; Luciana Bertoldi Nucci; Lucca Ortolan Hansen; Samanta Ramos Assuino

    2014-01-01

    OBJECTIVE: To evaluate the prevalence of weight excess in children and adolescents attending public and private schools of Campinas, Southeast Brazil, according to age group. METHODS: Cross-sectional study that enrolled 3,130 students from 2010 to 2012. The weight and the height were measured and the body mass index (BMI) was calculated. The students were classified by BMI Z-score/age curves of the World Health Organization (WHO)-2007 (thinness, normal weight, overweight and obesity) and by a...

  12. Gender and age differences in prevalence and incidence of child sexual abuse in Croatia

    OpenAIRE

    Ajduković, Marina; Sušac, Nika; Rajter, Miroslav

    2013-01-01

    Aim To examine age and gender differences in the prevalence and incidence of child sexual abuse, the level of acquaintance of the child and the perpetrator, and correlations between experiencing family violence and sexual abuse on a nationally representative sample of 11, 13, and 16 years old children. Method A probabilistic stratified cluster sample included 2.62% of the overall population of children aged 11 (n = 1223), 13 (n = 1188), and 16 (n = 1233) from 40 primar...

  13. Lifetime Prevalence, Age of Risk, and Genetic Relationships of Comorbid Psychiatric Disorders in Tourette Syndrome

    OpenAIRE

    Hirschtritt, Matthew E.; Paul C. Lee; Pauls, David L.; Dion, Yves; Grados, Marco A.; Illmann, Cornelia; King, Robert A.; Sandor, Paul; McMahon, William M; Lyon, Gholson J.; Cath, Danielle C.; Kurlan, Roger; Robertson, Mary M.; Osiecki, Lisa; Scharf, Jeremiah M.

    2015-01-01

    © 2015 American Medical Association. All rights reserved. Importance: Tourette syndrome (TS) is characterized by high rates of psychiatric comorbidity; however, fewstudies have fully characterized these comorbidities. Furthermore, most studies have included relatively fewparticipants (< 200), and none has examined the ages of highest risk for each TS-associated comorbidity or their etiologic relationship to TS.Objective: To characterize the lifetime prevalence, clinical associations, ages of ...

  14. Complex Covariance

    Directory of Open Access Journals (Sweden)

    Frieder Kleefeld

    2013-01-01

    Full Text Available According to some generalized correspondence principle the classical limit of a non-Hermitian quantum theory describing quantum degrees of freedom is expected to be the well known classical mechanics of classical degrees of freedom in the complex phase space, i.e., some phase space spanned by complex-valued space and momentum coordinates. As special relativity was developed by Einstein merely for real-valued space-time and four-momentum, we will try to understand how special relativity and covariance can be extended to complex-valued space-time and four-momentum. Our considerations will lead us not only to some unconventional derivation of Lorentz transformations for complex-valued velocities, but also to the non-Hermitian Klein-Gordon and Dirac equations, which are to lay the foundations of a non-Hermitian quantum theory.

  15. SNAP Participation in Preschool-Aged Children and Prevalence of Overweight and Obesity

    Science.gov (United States)

    Simmons, Shannon; Alexander, Jeffrey L.; Ewing, Helen; Whetzel, Stephanie

    2012-01-01

    Background: An increased prevalence of overweight and obesity for adults on government-funded nutrition assistance, such as the Supplemental Nutrition Assistance Program (SNAP), has been observed; however, this association among preschool-aged children is not well understood. Longitudinal research designs tracking changes in body mass…

  16. Prevalence, Formation, Maintenance, and Evaluation of Interdisciplinary Student Aging Interest Groups

    Science.gov (United States)

    Jones, Katherine J.; Vandenberg, Edward V.; Bottsford, Lisa

    2011-01-01

    The authors describe the prevalence, formation, maintenance, and evaluation of student aging interest groups. They conducted a cross-sectional electronic survey of the 46 academic medical centers funded by the Donald W. Reynolds Foundation. To evaluate their group of approximately 50 students, the authors conducted an electronic pretest and…

  17. Prevalence of Atopic Dermatitis in Chinese Children aged 1–7 ys

    Science.gov (United States)

    Guo, Yifeng; Li, Ping; Tang, Jianping; Han, Xiuping; Zou, Xiaoyan; Xu, Gang; Xu, Zigang; Wei, Fenglei; Liu, Qiang; Wang, Min; Xiao, Fengli; Zong, Wenkai; Shen, Chunping; Li, Jianhong; Liu, Jianzhong; Luo, Yongqi; Chang, Jing; Sheng, Nan; Dong, Chun; Zhang, Duo; Dai, Xing; Zhou, Jinjie; Meng, Chi; Niu, Hongxi; Shi, Xuemei; Zhang, Xinglian; Xiang, Juan; Xu, Haitao; Ran, Qin; Zhou, Yi; Li, Ming; Zhang, Hui; Cheng, Ruhong; Gao, Xinghua; Wang, Hua; Gu, Heng; Ma, Lin; Yao, Zhirong

    2016-01-01

    Prevalence of atopic dermatitis (AD) is increasing worldwide. Up to date, there has been no face-to-face nation-wide study in China. We aim to explore the prevalence of clinical diagnosed AD in children aged 1–7 ys in China. Twelve metropolises were chosen from different areas of China. In each region, we selected 4–10 kindergartens and 2–5 vaccination clinics randomly. A complete history-taking and skin examination were performed by dermatologists. The definite diagnosis of AD and the severity were determined by two or three dermatologists. All criteria concerned in UK diagnosis criteria, characteristic presentation of AD and atypical manifestations were recorded in detail. A total of 13998 children from 84 kindergartens and 40 vaccination clinics were included. The prevalence of AD was 12.94% by clinical diagnosis of dermatologists overall, with 74.6% of mild AD. Comparatively, prevalence of AD based on UK diagnostic criteria was 4.76%. This is the first face-to-face nation-wide study in Chinese children aged 1–7 ys, revealing that the prevalence of AD in children is closer to that of wealthier nations. PMID:27432148

  18. Prevalence

    Directory of Open Access Journals (Sweden)

    Mohammed Al-Darwish

    2014-07-01

    Conclusion: Results indicated that dental caries prevalence among school children in Qatar has reached critical levels, and is influenced by socio-demographic factors. The mean decayed, missing, and filled teeth values obtained in this study were the second highest detected in the Eastern Mediterranean region.

  19. Prevalence of Candida spp. among healthy denture and nondenture wearers with respect to hygiene and age.

    Science.gov (United States)

    Prakash, Bharathi; Shekar, Malathi; Maiti, Biswajit; Karunasagar, Indrani; Padiyath, Sreeshma

    2015-01-01

    Dentures are inert and nonshading surfaces and therefore get easily colonized by Candida species. Subsequent biofilm produced by them lead to denture stomatitis and candidiasis. This study was aimed to understand the prevalence of Candida species among healthy denture and nondenture wearers with respect to their age and hygiene status. Swabs were collected from 50 complete dentures and 50 non-denture wearers and processed on Sabouraud's dextrose agar. Identification of Candida species was done by staining and a battery of biochemical tests. Data obtained was correlated with age & oral hygiene and statistical analysis was performed. Candida was isolated from both denture and nondenture wearers. Prevalence of different Candida species was significantly higher in denture wearers and found predominated by C. albicans, C. tropicalis, C. dubliensis and C. glabrata. Among nondenture wearers, C. albicans and C. tropicalis were isolated. Prevalence of Candida increased with increasing age among denture wearers. Men presented declining denture hygiene compared to women with increasing age. In comparison to nondenture wearers, multispecies of Candida colonized the dentures thus presenting higher risk of candidiasis especially with increasing age.

  20. Prevalence of HLA-B27 in the New Zealand population: effect of age and ethnicity

    OpenAIRE

    Roberts, Rebecca L; Wallace, Mary C.; Jones, Gregory T.; van Rij, Andre M.; Tony R Merriman; Harrison, Andrew; White, Douglas; Stamp, Lisa K.; Ching, Daniel; Highton, John; Stebbings, Simon M

    2013-01-01

    Introduction HLA-B27 genotyping is commonly used to support a diagnosis of ankylosing spondylitis (AS). A recent study has suggested that HLA-B27 may adversely affect longevity. The objectives of this study were to determine, for the first time, the prevalence of HLA-B27 in the New Zealand population, and to test whether HLA-B27 prevalence declines with age. Methods 117 Caucasian controls, 111 New Zealand Māori controls, and 176 AS patients were directly genotyped for HLA-B27 using PCR-SSP. T...

  1. The anorexia of ageing: physiopathology, prevalence, associated comorbidity and mortality. A systematic review.

    Science.gov (United States)

    Malafarina, Vincenzo; Uriz-Otano, Francisco; Gil-Guerrero, Lucía; Iniesta, Raquel

    2013-04-01

    The physiological processes of ageing and factors prevalent in the elderly such as comorbidities and polypharmacy often cause loss of appetite in the elderly, which we call anorexia of ageing. Social factors, together with changes in the sensory organs, can be important causes of a reduction in both appetite and ingestion. This review assesses the regulation of appetite in the elderly and the development of anorexia of ageing. It also examines the prevalence of this type of anorexia, its associated comorbidities and mortality rates. We have reviewed 27 studies, with a total of 6208 patients. These reported changes in the secretion and response of both central and peripheral hormones that regulate appetite. Anorexia, very prevalent among hospitalized and institutionalized elderly people, is associated with comorbidity and represents a predictive factor for mortality. No treatment for it has been proved to be effective. The mechanism regulating ingestion in elderly people is complex and difficult to resolve. Comorbidity as a cause or a consequence of anorexia of ageing has become a research field of great interest in geriatrics. A correct nutritional evaluation is a fundamental part of an integrated geriatric assessment.

  2. Prevalence of anemia and correlated factors in the reproductive age women in rural areas of tabas.

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    Majid Sadeghian

    2013-09-01

    Full Text Available To find out the prevalence and relationship of anemia in reproductive age women in rural area of Tabas, center of Iran. Iron deficiency anemia is the most common nutritional problem, affecting about 41.8% of pregnant and 30.2% of non-pregnant women worldwide.A cross-sectional study was conducted on the random sample of 382 reproductive age women in rural areas of Tabas in March 2010. Independent sample t-test, one way analysis of variance (ANOVA and logistic regression were applied for the data analysis.The obtained data revealed a total response rate of 13.8% for prevalence of anemia, while 14.5% and 5.9% belonged to non-pregnant and pregnant participants, respectively. Low socioeconomic status (odds ratio 3.35 and high parity index (odds ratio 2.31 were associated with higher prevalence of anemia.Although this study was conducted in a rural area of Tabas, where their average incomes were lower than average income of major cities in Iran, the prevalence of anemia was lower than the rate reported in previous studies carried out in other locations of Iran, even in high risk (pregnant women groups.

  3. Estimating Cosmological Parameter Covariance

    CERN Document Server

    Taylor, Andy

    2014-01-01

    We investigate the bias and error in estimates of the cosmological parameter covariance matrix, due to sampling or modelling the data covariance matrix, for likelihood width and peak scatter estimators. We show that these estimators do not coincide unless the data covariance is exactly known. For sampled data covariances, with Gaussian distributed data and parameters, the parameter covariance matrix estimated from the width of the likelihood has a Wishart distribution, from which we derive the mean and covariance. This mean is biased and we propose an unbiased estimator of the parameter covariance matrix. Comparing our analytic results to a numerical Wishart sampler of the data covariance matrix we find excellent agreement. An accurate ansatz for the mean parameter covariance for the peak scatter estimator is found, and we fit its covariance to our numerical analysis. The mean is again biased and we propose an unbiased estimator for the peak parameter covariance. For sampled data covariances the width estimat...

  4. Bullying behaviors among Chinese school-aged youth: a prevalence and correlates study in Guangdong Province.

    Science.gov (United States)

    Wu, Jie; He, Yuan; Lu, Ciyong; Deng, Xueqing; Gao, Xue; Guo, Lan; Wu, Hong; Chan, Fanfan; Zhou, Ying

    2015-02-28

    Bullying among school-aged youth is a common issue worldwide and is increasingly being recognized as an important problem affecting both victims and perpetrators. Most of the bullying studies have been conducted in western countries, and their implications in other regions are limited due to different cultural contexts. The goal of our study is to identify the prevalence of bullying and its correlates school-aged youth in Guangdong province. In total, 1098 (7.1%) students reported having bullied other students, 744 (4.8%) students reported having been bullied by other students and 396 (2.6%) students reported having both bullied other students and been bullied by other students. There was a strong association between bullying others as well as being bullied and suicidal ideations, suicidal attempts, and self-harm behaviors. The prevalence of bullying and its associations with delinquent behaviors warrant the importance of school facility based preventive intervention taking into account both victims and perpetrators.

  5. Age-specific Prevalence of Antibodies to Hepatitis A in Children and Adolescents from Rio de Janeiro, Brazil, 1978 and 1995: Relationship of Prevalence to Environmental Factors

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    Claudia L Vitral

    1998-01-01

    Full Text Available The age-specific prevalence of antibodies to hepatitis A virus (anti-HAV was determined in two different population groups with low socio-economic status from Rio de Janeiro city, Brazil, whose serum samples were collected 17 years apart (Population 1, 1978; Population 2, 1995. In Population 2, analysis of the anti-HAV prevalence was also carried out with respect to environmental factors. Population 1 was composed of 520 stored sera collected from the umbilical cord of term neonates and children aged 1 month to 6 years. In population 2, 720 serum samples were collected from children and adolescents with ages ranging from 1 to 23 years. The overall prevalence rate of anti-HAV in Population 1 and Population 2 was 65.6% and 32.1%, respectively. In Population 1, the anti-HAV prevalence reached 88% at the age of 3, while in Population 2, it increased from 4.5% in children under the age of 3 to 66% in the group of adolescents over the age of 14. The low exposure to HAV infection in younger children from Population 2 could be a result of improved environmental hygiene and sanitation, as demonstrated by the presence of piped water, waste and sewage disposal systems in most houses from this population group. These findings indicate a possible change in the prevalence of hepatitis A in Rio de Janeiro

  6. Prevalence of missing and impacted third molars in adults aged 25 years and above

    OpenAIRE

    Jung, Yun-Hoa; Cho, Bong-Hae

    2013-01-01

    Purpose The purpose of this study was to determine the prevalence of missing and impacted third molars in people aged 25 years and above. Materials and Methods The study sample of 3,799 patients was chosen randomly from patients who visited Pusan National University Dental Hospital and had panoramic radiographs taken. The data collected included presence and impaction state, angulation, and depth of impaction of third molars, and radiographically detected lesions of third molars and adjacent ...

  7. Prevalence of Anemia and Associated Factors in Child Bearing Age Women in Riyadh, Saudi Arabia

    OpenAIRE

    AlJohara M. AlQuaiz; Ashry Gad Mohamed; Khoja, Tawfik A.M.; Abdullah AlSharif; Shaffi Ahamed Shaikh; Hamad Al Mane; Abdallah Aldiris; Ambreen Kazi; Durdana Hammad

    2013-01-01

    Objective. To determine the prevalence and risk factors for anemia in child bearing age women in Riyadh, Saudi Arabia. Design. Cross-sectional survey was conducted using two-stage cluster sampling. 25 clusters (primary health care centers (PHCC)) were identified from all over Riyadh, and 45–50 households were randomly selected from each cluster. Eligible women were invited to PHCC for questionnaire filling, anthropometric measurements, and complete blood count. Blood hemoglobin was measured w...

  8. The prevalences of impaired fasting glucose and diabetes mellitus in working age men of North China: Anshan Worker Health Survey

    OpenAIRE

    Liu, Lei; ZHOU, CHUANG; Du, Hang; Zhang, Kai; Huang, Desheng; Wu, Jingyang; Anshan Worker Health Survey Group,

    2014-01-01

    To investigate the prevalence of impaired fasting glucose (IFG) and total diabetes mellitus (DM) including known diabetes and newly diagnosed diabetes in working age men of North China. A cross-section study was conducted at health medical center of Ansteel Group Hospital in Anshan city of China. 37,345 males between 20–60 years of age were recruited in this study. Age-standardized prevalence of IFG and total DM in these working age men were 25.3% and 8.4%, respectively. The prevalence of IFG...

  9. Cigarette Smoking among Adolescents in Northwest Ohio: Correlates of Prevalence and Age at Onset

    Directory of Open Access Journals (Sweden)

    James H. Price

    2008-12-01

    Full Text Available This study examined the prevalence and correlates of smoking initiation among adolescents. We have used data from adolescents (n=5,392 ages 10-18 who participated in the 2003 Tobacco Survey, a representative sample of adolescents in Northwest Ohio. A selfreport of cigarette smoking was obtained using a questionnaire administered in classrooms. Data were analyzed using weighted chi-square and multiple logistic regressions in SAS that accounted for the survey design. The prevalence rates for adolescents that ever tried smoking were 7.4% in elementary (grades 4-5; 17.7% in middle (grades 6-8, and 41.4% in high (grades 9-12 schools, respectively. The highest prevalence rate was among Hispanics. Having a close friend that smoked and a smoker at home correlated significantly with both initiation of smoking and smoking at an earlier age. Smoking was correlated with low academic achievement among adolescents in all grades. Students who reported smoking by parents or siblings were significantly more likely to start smoking at an earlier age, compared to other students living in a non-smoking home environment. Smoking prevention program should include components focused on adolescents’ home environment and should start as early as the 4th grade.

  10. Prevalence and clinical profile of diabetes mellitus in productive aged urban Indonesians

    OpenAIRE

    Mihardja, Laurentia; Soetrisno, Uken; Soegondo, Sidartawan

    2013-01-01

    Abstract Aims/Introduction To estimate the prevalence and clinical profile of diabetes mellitus in productive aged urban Indonesians based on the National Basic Health Research 2007. Materials and Methods The statistical analyses of a cross‐sectional survey included the data of 15,332 adults, aged 18–55 years, living in an urban area. Blood glucose was measured by an automatic clinical chemistry analyzer by 2‐h, 75‐g post glucose load after an overnight fast. Weight, height, waist circumferen...

  11. The prevalence of lactase deficiency and lactose intolerance in Chinese children of different ages

    Institute of Scientific and Technical Information of China (English)

    2000-01-01

    Objective To determine lactose metabolism and lactase activity in Chinese children of different ages, prevalence of lactase deficiency (LD), and lactose intolerance (LI). Methods All 1168 healthy subjects between 3 and 13 years were recruited from schools in four large cities in China. They were screened by a 25 g lactose tolerance test.Some subjecls were challenged with .50 g milk powder on different days. Both indicators,the expiratory H2 concentration and intolerance symptoms, were analyzed. Results LD occurred in 38.5% of children in the 3-5 year age group, and 87% of the 7-8 year and 11-13 year old groups. The age of occurrence for LD may be at 7-8 years among Chinese children. The prevalence of LI among Chinese children was 12.2% alage 3-5 years, 33.1% at age 7-8 years, and 30.5% al age 11-13 years, respectively. Conclusion The results demonstrate that LD is very common in Chinese children from these four cities. LD and LI have a dose dependent response: lactose absorption and symptorms are based on lactase activity. The relationship between breast feeding history (or the history of cow milk intake) and lactase activity among Chinese children has not been established.

  12. Gender and age groups interactions in the quantification of bone marrow fat content in lumbar spine using 3T MR spectroscopy: A multivariate analysis of covariance (Mancova)

    International Nuclear Information System (INIS)

    Introduction: There is an age-related conversion of red to yellow bone marrow in the axial skeleton, with a gender-related difference less well established. Our purpose was to clarify the variability of bone marrow fat fraction (FF) in the lumbar spine due to the interaction of gender and age groups. Methods: 44 healthy volunteers (20 males, 30–65 years old and 24 females, 30–69 years old) underwent 3T magnetic resonance spectroscopy (MRS) and conventional MRI examination of the lumbar spine; single-voxel spectrum was acquired for each vertebral body (VB). After controlling body mass index (BMI), a two-way between-groups multivariate analysis of covariance (MANCOVA) assessed the gender and age group differences in FF quantification for each lumbar VB. Results: There was a significant interaction between gender and age group, p = .017, with a large effect size (partial η2 = .330). However the interaction explained only 33% of the observed variance. Main effects were not statistically significant. BMI was non-significantly related to FF quantification. Conclusions: Young males showed a high FF content, which declined in the 4th decade, then increased the next 3 decades to reach a FF content just below the initial FF means. Females’ FF were low in the 3rd decade, depicted an accelerated increase in the 4th decade, then a gradual increase the next 3 decades to reach a FF content similar to males’ values. Our findings suggest that quantification of bone marrow FF using MRS might be used as a surrogate biomarker of bone marrow activity in clinical settings

  13. Gender and age groups interactions in the quantification of bone marrow fat content in lumbar spine using 3T MR spectroscopy: A multivariate analysis of covariance (Mancova)

    Energy Technology Data Exchange (ETDEWEB)

    Roldan-Valadez, Ernesto, E-mail: ernest.roldan@usa.net [Magnetic Resonance Unit, Medica Sur Clinic and Foundation, Mexico City (Mexico); Piña-Jimenez, Carlos [Magnetic Resonance Unit, Medica Sur Clinic and Foundation, Mexico City (Mexico); Favila, Rafael [GE Healthcare, Mexico City (Mexico); Rios, Camilo [Neurochemistry Department, Mexican National Institute of Neurology and Neurosurgery, Mexico City (Mexico)

    2013-11-01

    Introduction: There is an age-related conversion of red to yellow bone marrow in the axial skeleton, with a gender-related difference less well established. Our purpose was to clarify the variability of bone marrow fat fraction (FF) in the lumbar spine due to the interaction of gender and age groups. Methods: 44 healthy volunteers (20 males, 30–65 years old and 24 females, 30–69 years old) underwent 3T magnetic resonance spectroscopy (MRS) and conventional MRI examination of the lumbar spine; single-voxel spectrum was acquired for each vertebral body (VB). After controlling body mass index (BMI), a two-way between-groups multivariate analysis of covariance (MANCOVA) assessed the gender and age group differences in FF quantification for each lumbar VB. Results: There was a significant interaction between gender and age group, p = .017, with a large effect size (partial η{sup 2} = .330). However the interaction explained only 33% of the observed variance. Main effects were not statistically significant. BMI was non-significantly related to FF quantification. Conclusions: Young males showed a high FF content, which declined in the 4th decade, then increased the next 3 decades to reach a FF content just below the initial FF means. Females’ FF were low in the 3rd decade, depicted an accelerated increase in the 4th decade, then a gradual increase the next 3 decades to reach a FF content similar to males’ values. Our findings suggest that quantification of bone marrow FF using MRS might be used as a surrogate biomarker of bone marrow activity in clinical settings.

  14. Trends in smoking prevalence in Danish adults, 1964-1994. The influence of gender, age, and education

    DEFF Research Database (Denmark)

    Osler, M; Prescott, E; Gottschau, A;

    1998-01-01

    BACKGROUND: Studies of time trends in smoking prevalence provide a better understanding of the determinants of smoking. The present study analyses changes over time in the prevalence of smoking and heavy smoking in relation to sex, age, and education. METHODS: Data on smoking behaviour were...... the effects of sex, age, education, time period, and study group on the prevalence of smoking and of heavy smoking were assessed. RESULTS: Smoking was least prevalent in women, in the oldest age group (more than 70 years), and among those with 8 years or more of school education. During the study period (from......, and among the well educated. During the study period, the unadjusted prevalence of heavy smoking decreased from 52% to 38% in men, while it increased from 17% to 21% in women. The multivariate analysis showed that the time trend for heavy smoking only depended on sex, while educational attainment and age...

  15. Prevalence of elimination dysfunction, among primary school age children in Sari

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    M. Basiri,

    2008-01-01

    Full Text Available AbstractBackground and Purpose: Elimination dysfunction is referred to have various difficulties in urination and defecation, such as urinary frequency, delayed with difficulty in voiding or defecation. The prevalence of elimination dysfunction has been varied in different studies, as 21% of children experience elimination dysfunction during their childhood period. Presently, there are no studies pertaining to this difficulty in our country. Therefore, we carried out a descriptive study in primary schools from the Sari Township, regarding voiding and defecation dysfunction among children, and also we identified the epidemiology of the disease, in order to solve problems by implementing teaching programs and screening methods.Materials and Methods: This cross-sectional study was done on Primary school age students in the Sari Township, during 2007 through 2008. Considering the prevalence of elimination dysfunction (15-25%, confidence coefficient 95%, SE 10%, and the sample size of 2,200 were randomly and equally selected from different parts of the township among the two-sex groups. A standard questionnaire including demographic characteristics and 10 questions on voiding status, in addition to 19 questions regarding defecation status was prepared. Questionnaires were distributed to the students by responsible school personnel and then referred to parents for completion. Data was analyzed by SPSS software and descriptive statistics (Frequency, Mean, and Standard Deviation. Chi Square test (χ² and Student T-test were used to compare the Means. P<0.05 was considered significant.Results: Of 2201 primary school age students, 48.7% were girls. The mean age was 8.96±1.43 year. Voiding and defecation dysfunction was reported in 38.4% and 29% of the cases respectively. There was no significant relationship between prevalence of voiding dysfunction and other factors such as mean age, sex and level of education; however, there was a significant

  16. Prevalence of weight excess according to age group in students from Campinas, SP, Brazil

    Directory of Open Access Journals (Sweden)

    Silvia Diez Castilho

    2014-06-01

    Full Text Available OBJECTIVE: To evaluate the prevalence of weight excess in children and adolescents attending public and private schools of Campinas, Southeast Brazil, according to age group.METHODS: Cross-sectional study that enrolled 3,130 students from 2010 to 2012. The weight and the height were measured and the body mass index (BMI was calculated. The students were classified by BMI Z-score/age curves of the World Health Organization (WHO-2007 (thinness, normal weight, overweight and obesity and by age group (7-10, 11-14 and 15-18 years. Multinomial logistic regression analysis was applied to verify variables associated to overweight and obesity.RESULTS: Among the 3,130 students, 53.7% attended public schools and 53.4% were girls. The prevalence of weight excess (overweight or obesity was higher in private schools (37.3% than in public ones (32.9% and among males (37.5%, compared to females (32.7%; p<0.05. The chance of having weight excess in children aged 7-10 years was more than twice of those over 15 years old (OR 2.4; 95%CI 2.0-3.0 and it was 60% higher for the group with 11-14 years old (OR 1.6; 95%CI 1.3-2.0. The chance of being obese was three times higher in 7-10 years old children than in the adolescents with 15-18 years old (OR 4.4; 95%CI 3.3-6.4 and 130% higher than the group with 11-14 years old (OR 2.3; 95%CI 1.6-3.2.CONCLUSIONS: The prevalence of weight excess in Campinas keeps increasing at an alarming rate, especially in the younger age group.

  17. Trends of smoking prevalence among Lithuanian school-aged children in 1994-2006.

    Science.gov (United States)

    Zaborskis, Apolinaras; Sumskas, Linas; Zemaitiene, Nida; Grabauskas, Vilius; Veryga, Aurelijus; Petkevicius, Robertas

    2009-01-01

    BACKGROUND. Despite much effort spent on antismoking programs in schools in different countries, limited effects have been observed in many cases. Evidence from European countries shows that active tobacco control actions such as ban on tobacco advertising, increase of tobacco taxes could lead to successful results. Our study was aimed to analyze time trends on smoking in Lithuanian school-aged children during the period of 1994-2006 in the context of antismoking policies, which were implemented in Lithuania. MATERIAL AND METHODS. This study was a part of WHO Cross-National Health Behavior in School-Aged Children (HBSC) study carried out in Lithuania. The standardized methods of international HBSC study protocol were applied. Stratified random representative samples of 5428, 4513, 5645, and 5632 students aged 11, 13, and 15 years were included into school-based anonymous questionnaire surveys in 1994, 1998, 2002, and 2006, respectively (spring semester). Questions on frequency of smoking, age of initiation and other questions were included. Response rates of each of these four questionnaire surveys were higher than 90%. RESULTS. Smoking behavior was more common among boys. The prevalence gap in smoking between boys and girls diminished during period of observation. Prevalence of smoking increased significantly among boys during the period of 1994-2002 (11.3%, 19.8%, and 23.6% in 1994, 1998, and 2002, respectively), but started to decline after (17.3% in 2006, P0.05). Urban girls have reported smoking more frequently in comparison with rural girls. CONCLUSIONS. An increase in tobacco smoking among school-aged children was observed in Lithuania during 1994-2002. A decrease in prevalence of smoking was seen during the period of 2002-2006. These trends could be related to the implementation of tobacco control measures in Lithuania. PMID:19996667

  18. Prevalence and age-dependent occurrence of intestinal protozoan infections in suckling piglets.

    Science.gov (United States)

    Damriyasa, I Made; Bauer, Christian

    2006-01-01

    A cross-sectional survey was performed on 20 pig breeding farms in southern Hesse, central Germany, to evaluate the prevalence and age-dependent occurrence of intestinal protozoan parasites in unweaned piglets. Faecal samples of 514 clinically unaffected piglets of different age (Balantidium coli (16 of 20 farms), Entamoeba sp. (15), Jodamoeba sp. (14), Isospora (I.) suis (9), Chilomastix sp. (6) and Eimeria spp. (6). The protozoan species differed in the start and course of (oo)cyst excretion. I. suis oocysts and Jodamoeba cysts were detected already in the first week of life whereas shedding of the other parasites started later on. The prevalence of Isospora oocyst excretion increased to a maximum (18%) in 2-3 weeks old animals followed by a sharp decline. The proportion of Balantidium, Entamoeba or Jodamoeba positive suckling piglets continously increased until the age of 5-7 weeks to 60%, 52% and 22%, respectively, whereas that of Chilomastix positive animals remained on a low level of 8-12% independent of the age. Eimeria oocysts were found transiently in the faeces of 1-4 weeks old piglets. PMID:17009710

  19. Evaluating the Prevalence of Small for Gestational Age and Its Associated Risk Factors

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    Barati

    2016-03-01

    Full Text Available Background Small for gestational age (SGA fetuses have birth weights below 10th percentile or abdominal circumference less than 10th percentile for gestational age Objectives This study aimed to determine the prevalence of SGA and its associated risk factors in Iran. Patients and Methods This is a retrospective study. A total of 341 pregnant women were evaluated in fetal health care clinic of perinatology from January 2013 to January 2014. Results Of 312 pregnant women, 33 had SGA fetuses. The average of body mass index (BMI was lower in SGA group than non-SGA. Pulsatility index has no stastical meaningful between SGA and nonSGA groups. In Gestational age had no difference between 2 groups. Severe SGA (< 3rd centile estimated fetal weight was observed in 2.6% of all cases. Conclusions In conclusion, the prevalence of SGA was approximately one tenth of all pregnancies. SGA incidence was associated with nulliparity and more frequently seen in lower age group.

  20. Obesity prevalence among low-income, preschool-aged children - United States, 1998-2008.

    Science.gov (United States)

    2009-07-24

    Childhood obesity continues to be a leading public health concern that disproportionately affects low-income and minority children. Children who are obese in their preschool years are more likely to be obese in adolescence and adulthood and to develop diabetes, hypertension, hyperlipidemia, asthma, and sleep apnea. One of the Healthy People 2010 objectives (19-3) is to reduce to 5% the proportion of children and adolescents who are obese. CDC's Pediatric Nutrition Surveillance System (PedNSS) is the only source of nationally compiled obesity surveillance data obtained at the state and local level for low-income, preschool-aged children participating in federally funded health and nutrition programs. To describe progress in reducing childhood obesity, CDC examined trends and current prevalence in obesity using PedNSS data submitted by participating states, territories, and Indian tribal organizations during 1998-2008. The findings indicated that obesity prevalence among low-income, preschool-aged children increased steadily from 12.4% in 1998 to 14.5% in 2003, but subsequently remained essentially the same, with a 14.6% prevalence in 2008. Reducing childhood obesity will require effective prevention strategies that focus on environments and policies promoting physical activity and a healthy diet for families, child care centers, and communities.

  1. Variations in Community Prevalence and Determinants of Recreational and Utilitarian Walking in Older Age.

    Science.gov (United States)

    Procter-Gray, Elizabeth; Leveille, Suzanne G; Hannan, Marian T; Cheng, Jie; Kane, Kevin; Li, Wenjun

    2015-01-01

    Background. Regular walking is critical to maintaining health in older age. We examined influences of individual and community factors on walking habits in older adults. Methods. We analyzed walking habits among participants of a prospective cohort study of 745 community-dwelling men and women, mainly aged 70 years or older. We estimated community variations in utilitarian and recreational walking, and examined whether the variations were attributable to community differences in individual and environmental factors. Results. Prevalence of recreational walking was relatively uniform while prevalence of utilitarian walking varied across the 16 communities in the study area. Both types of walking were associated with individual health and physical abilities. However, utilitarian walking was also strongly associated with several measures of neighborhood socioeconomic status and access to amenities while recreational walking was not. Conclusions. Utilitarian walking is strongly influenced by neighborhood environment, but intrinsic factors may be more important for recreational walking. Communities with the highest overall walking prevalence were those with the most utilitarian walkers. Public health promotion of regular walking should take this into account. PMID:26339507

  2. Caries prevalence and risk factors among children aged 0 to 36 months

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    Santos Ana Paula Pires dos

    2002-01-01

    Full Text Available The aim of this study was to assess the prevalence of caries and risk factors in outpatients of the Pediatric Ambulatory of the Pedro Ernesto University Hospital aging up to 36 months. After signing informed consent forms, the parents answered a structured questionnaire in order to evaluate risk factors for dental caries, including socioeconomic status, oral hygiene and dietary habits. A single investigator carried out the dental examination which assessed the presence of caries, biofilm and gingival bleeding. The data were analyzed by means of the Epi Info program, utilizing the chi-squared test. The children?s mean age was 22.9 months. The prevalence of caries, including white spot lesions, was 41.6%, and the mean def-s was 1.7 (± 2.5. The most affected teeth were the maxillary incisors, and the most common lesion was the white spot. No significant associations were found between the prevalence of caries and socioeconomic status, frequency of oral hygiene, nocturnal bottle- and breast-feeding or cariogenic food and beverage intake during the day. However, the association between caries and oral hygiene quality (dental biofilm was statistically significant (p < 0.001. The results suggest that the presence of a thick biofilm was the most important factor for the occurrence of early childhood caries in the evaluated sample.

  3. PREVALENCE OF ANAEMIA AMONG CHILDREN AGED 12 YEARS AND YOUNGER IN NORTH EAST INDIA

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    Rajkumari Rupabati

    2016-02-01

    Full Text Available BACKGROUND AND OBJECTIVE Anaemia is one of the most important public health problem among children. The infants, preschool children, adolescents and pregnant women are at highest risk of nutritional anaemia. The aim of this study was to evaluate the prevalence of anaemia and its correlation to age, gender, haemoglobin values and magnitude of anaemia among the children of North East India. METHODS A cross sectional study was conducted in a tertiary care hospital between October 2013 to September 2014. A total of 500 children in the age group 0 to 12 years were enrolled after obtaining written informed consent from the parents. Haemoglobin estimation was done by Sahli’s method using finger prick blood samples. As per WHO recommendation, haemoglobin values below 11 gm/dl was considered anaemic. Statistical data were analysed. RESULTS The overall prevalence of anaemia was 71.2% with males having 5.2%higher than females. The majority of age group comprises 1 to ≤5 years (36.0% and 83.3% of them were anaemic. The highest value of haemoglobin estimated was 14.8 gm/dl with the lowest value of 5.2 gm/dl. The mean haemoglobin level was 10.76±1.21 gm/dl. 53.4% children were mildly anaemic. Both male and female children were affected more with mild anaemia than other types of anaemia. CONCLUSION Our results suggest that all the children should be screened for anaemia irrespective of age and sex as the prevalence is high. Early intervention and appropriate measures should be taken to prevent from anaemia and its associated diseases.

  4. Characteristics of Adults with Down Syndrome: prevalence of age-related conditions

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    Angelo eCarfì

    2014-12-01

    Full Text Available Introduction. In the last decades, life expectancy of persons with Down syndrome (DS has dramatically increased and it is estimated that they will be living as long as the general population within a generation. Despite being included among the progeroid syndromes, because of the presence of features typically observed in older adults, DS is still regarded as a disease of pediatric interest. Because limited knowledge is available on the clinical characteristics of adults with DS, this study aimed to assess clinical and non-clinical features of this population and to describe similarities to the geriatric population. Methods. In this study, we described 60 adults with DS evaluated at the Day Hospital of the Geriatric Department of the Policlinico A. Gemelli, Università Cattolica del Sacro Cuore in Rome. Individuals were assessed through a standardized protocol. Results. The mean age of study participants was 38 years (range, 18 to 58 years and 42 (70.0% were women. Geriatric conditions were highly prevalent: severe cognitive impairment was diagnosed in 39 (65.0% participants, behavioral symptoms were present in 25 (41.7% and functional impairment in 23 (38.3%. Six (10.0% participants lived in institutions and 11 (18.3% were diagnosed as obese. The mean number of drugs used was 2.4; use of psychotropic drugs was highly prevalent. The most common chronic diseases were thyroid problems (44, 73.3%, followed by mood disorders (19, 31.7%, osteoporosis (18, 30.0% and cardiac problems (10, 16.7%. Geriatric conditions and chronic diseases were more prevalent among participants aged ≥40 years. Conclusions. Several similarities between older adults and adults with DS were observed. Comorbidities, geriatric conditions, cognitive and functional deficits and social problems are highly prevalent in both populations, contributing to the high complexity of these patients’ assessment and treatment.

  5. Hypertension prevalence and awareness in older Irish adults: Evidence from the Irish Longitudinal Study on Ageing (TILDA)

    OpenAIRE

    Murphy, Catriona; Kearney, P; Shelley, E; Fahey, T; Dooley, C; Kenny, RA

    2014-01-01

    Introduction: Hypertension prevalence is increasing worldwide: population ageing and an increase in the prevalence of obesity are contributing to this rise. Hypertension is a major modifiable risk factor for stroke, coronary heart disease, end stage renal disease and has been associated with cognitive impairment. The aim of this study is to determine the prevalence of hypertension and to identify determinants of awareness of hypertension in older Irish adults. Methods: The Irish Longitudi...

  6. [Categorical and dimensional assessment of "psychopathy" in German offenders. Prevalence, gender differences and age factors].

    Science.gov (United States)

    Ullrich, S; Paelecke, M; Kahle, I; Marneros, A

    2003-11-01

    The personality construct "psychopathy" is of utmost importance in legal prognosis. In the last 20 years, a multitude of empirical research proved the predictive validity of this concept concerning the degree of dangerousness represented by an offender. In the present study, a representative, nonselected sample of 416 offenders was examined using the Screening Version of the Psychopathy Checklist (PCL:SV). The data were analysed both categorically and dimensionally according to the three-factor model proposed by Cooke and Michie. In comparison to North American Studies the prevalence of high scorers was significantly lower, implicating intercultural differences. Analyses of the effects of gender yielded higher scores on each of the three factors in male offenders. Concerning different age cohorts, it turned out that the arrogant and deceitful interpersonal style and deficient affective experience remained stable, whereas the impulsive and irresponsible behavioral style decreased with increasing age. Therefore, our results point out intercultural differences already shown in the prevalence of "psychopathy" and confirm the effects of gender and age concerning this construct. PMID:14598037

  7. Correlation between tea consumption and prevalence of hypertension among Singaporean Chinese residents aged ⩾40 years.

    Science.gov (United States)

    Li, W; Yang, J; Zhu, X S; Li, S C; Ho, P C

    2016-01-01

    By a cross-sectional epidemiology study, we attempted to correlate the consumption of tea and/or health supplements, living habits and socio-demographic factors to the prevalence of hypertension among Singaporean Chinese residents. Singaporean Chinese residents aged ⩾40 years were randomly selected and interviewed face-to-face by clinical research assistants. Hypertension was defined as measured systolic blood pressure at least 140 mm Hg and/or diastolic blood pressure at least 90  mmHg or self-reported history/treatment for hypertension. The prevalence of hypertension among the whole investigated population (N=1184, 58.27% females) was 49.73% and the prevalence increased to 66.47% in the sub-population aged ⩾60 years. High risk of hypertension was associated with age ⩾60 years (odds ratio (OR): 4.15-4.19, P25 kg m(-2), OR: 2.10-2.11, Ptea at least 150 ml per week was associated with lower hypertension risk (OR: 0.63, 95% confidence interval (CI): 0.43-0.91, Ptea and British tea was associated with higher reduction in the risk of hypertension (OR: 0.58, 95% CI: 0.39-0.85, Ptea, especially green tea and British tea, was associated with lowering the risk of hypertension. On the other hand, consumption of coffee could be a risk factor of hypertension. These findings may provide useful information for health promotion to reduce risk of hypertension and warrant further study to confirm and elucidate such association.

  8. Prevalence of premenstrual syndrome among women of child-bearing age with regular menstrual cycle

    Directory of Open Access Journals (Sweden)

    Nodira Khodjaeva

    2013-11-01

    Full Text Available The study on prevalence of premenstrual syndrome (PMS with various severities was conducted in a cohort of fertile female residents of Tashkent aged from 18 to 30. Clinical and medical history data on psycho-emotional and physical PMS symptoms was put into a specially developed card-questionnaire. Severity of symptoms was determined by total score to fill in a PMS symptom scale on the basis of the examinees’ self-observation. The associations of PMS with social-demographic factors, such as, level of education, employment status, sexual satisfaction and stress index were analyzed.

  9. Prevalence of depression in general practice patients over 75 years of age

    OpenAIRE

    Jack, M.A.; Stobo, S.A.; Scott, L A; Sahgal, A.; Jachuck, S J

    1988-01-01

    The prevalence of depression among 74 male and 211 female patients aged 75 years or over registered with a group general practice was assessed, using the geriatric depression scale. Test scores of 0- 10, suggesting no depressive illness, were observed in 63 (85%) men and 172 (82%) women. Mild depression (scores 11-20) was observed in 10 (14%) men and 36(17%) women and severe depression (scores 21-30) in one (1%) man and three (1%) women. No significant statistical association was found with a...

  10. Comparison of age-specific cataract prevalence in two population-based surveys 6 years apart

    OpenAIRE

    Rochtchina Elena; Wang Jie; Tan Ava; Mitchell Paul

    2006-01-01

    Abstract Background In this study, we aimed to compare age-specific cortical, nuclear and posterior subcapsular (PSC) cataract prevalence in two surveys 6 years apart. Methods The Blue Mountains Eye Study examined 3654 participants (82.4% of those eligible) in cross-section I (1992–4) and 3509 participants (75.1% of survivors and 85.2% of newly eligible) in cross-section II (1997–2000, 66.5% overlap with cross-section I). Cataract was assessed from lens photographs following the Wisconsin Cat...

  11. Behavioral Risk Factors: Selected Metropolitan Area Risk Trends (SMART) MMSA Age-adjusted Prevalence Data (2011 to Present)

    Data.gov (United States)

    U.S. Department of Health & Human Services — 2011 to present. BRFSS SMART MMSA age-adjusted prevalence combined land line and cell phone data. The Selected Metropolitan Area Risk Trends (SMART) project uses...

  12. The Prevalence of Campylobacter amongst a Free-Range Broiler Breeder Flock Was Primarily Affected by Flock Age

    OpenAIRE

    Colles, Frances M; McCarthy, Noel D.; Ruth Layton; Maiden, Martin C. J.

    2011-01-01

    Campylobacter successfully colonizes broiler chickens, but little is known about the longer term natural history of colonization, since most flocks are slaughtered at an immature age. In this study, the prevalence and genetic diversity of Campylobacter colonizing a single free-range broiler breeder flock was investigated over the course of a year. The age of the flock was the most important factor in determining both the prevalence and diversity of Campylobacter over time. There was no correl...

  13. Diarrhea Prevalence, Care, and Risk Factors Among Poor Children Under 5 Years of Age in Mesoamerica.

    Science.gov (United States)

    Colombara, Danny V; Hernández, Bernardo; McNellan, Claire R; Desai, Sima S; Gagnier, Marielle C; Haakenstad, Annie; Johanns, Casey; Palmisano, Erin B; Ríos-Zertuche, Diego; Schaefer, Alexandra; Zúñiga-Brenes, Paola; Zyznieuski, Nicholas; Iriarte, Emma; Mokdad, Ali H

    2016-03-01

    Care practices and risk factors for diarrhea among impoverished communities across Mesoamerica are unknown. Using Salud Mesoamérica Initiative baseline data, collected 2011-2013, we assessed the prevalence of diarrhea, adherence to evidence-based treatment guidelines, and potential diarrhea correlates in poor and indigenous communities across Mesoamerica. This study surveyed 14,500 children under 5 years of age in poor areas of El Salvador, Guatemala, Mexico (Chiapas State), Nicaragua, and Panama. We compared diarrhea prevalence and treatment modalities using χ(2) tests and used multivariable Poisson regression models to calculate adjusted risk ratios (aRRs) and 95% confidence intervals (CIs) for potential correlates of diarrhea. The 2-week point prevalence of diarrhea was 13% overall, with significant differences between countries (P < 0.05). Approximately one-third of diarrheal children were given oral rehydration solution and less than 3% were given zinc. Approximately 18% were given much less to drink than usual or nothing to drink at all. Antimotility medication was given to 17% of diarrheal children, while antibiotics were inappropriately given to 36%. In a multivariable regression model, compared with children 0-5 months, those 6-23 months had a 49% increased risk for diarrhea (aRR = 1.49, 95% CI = 1.15, 1.95). Our results call for programs to examine and remedy low adherence to evidence-based treatment guidelines. PMID:26787152

  14. Low Prevalence of Iron and Vitamin A Deficiency among Cambodian Women of Reproductive Age.

    Science.gov (United States)

    Wieringa, Frank T; Sophonneary, Prak; Whitney, Sophie; Mao, Bunsoth; Berger, Jacques; Conkle, Joel; Dijkhuizen, Marjoleine A; Laillou, Arnaud

    2016-04-01

    Nearly half of women of reproductive age (WRA) in Cambodia are anemic. To guide interventions, national data on nutritional causes of anemia, including iron deficiency and vitamin A deficiency, are needed. In 2012, a national household survey in WRA on antibodies to routine vaccine-preventable disease immunity was performed. We used serum samples from this survey to estimate the prevalence of iron and vitamin A deficiency in 2112 Cambodian WRA, aged 15 to 39 years. Iron deficiency was classified as low or marginal iron stores (ferritin concentrations corrected for inflammation iron deficient erythropoiesis (soluble transferrin receptor concentrations >8.3 mg/L; sTfR), or low total body iron (TBI) derived from Fer and sTfR concentrations (status was classified using retinol binding protein (RBP) concentrations corrected for inflammation as deficient (iron stores, low TBI and iron deficient erythropoiesis was 8.1%, 5.0% and 9.3% respectively. Almost 40% of the women had marginal iron stores. Iron status was better in women living in urban areas compared to rural areas (p deficiency was iron and vitamin A deficiency to the high prevalence of anemia in Cambodian WRA may be limited. The etiology of anemia in Cambodia needs to be elucidated further to guide current policies on anemia.

  15. Intellectual Disability in a Birth Cohort: Prevalence, Etiology, and Determinants at the Age of 4 Years

    Science.gov (United States)

    Karam, Simone M.; Barros, Aluísio J.D.; Matijasevich, Alícia; dos Santos, Iná S.; Anselmi, Luciana; Barros, Fernando; Leistner-Segal, Sandra; Félix, Têmis M.; Riegel, Mariluce; Maluf, Sharbel W.; Giugliani, Roberto; Black, Maureen M.

    2016-01-01

    Background Intellectual disability (ID), characterized by impairments in intellectual function and adaptive behavior, affects 1-3% of the population. Many studies investigated its etiology, but few are cohort studies in middle-income countries. Aims To estimate prevalence, etiology, and factors related to ID among children prospectively followed since birth in a Southern Brazilian city (Pelotas). Methods In 2004, maternity hospitals were visited daily and births were identified. Live-born infants (n = 4,231) whose family lived in the urban area have been followed for several years. At the age of 2 and 4 years, performances in development and intelligence tests were evaluated using the Battelle Developmental Inventory and Wechsler Intelligence Scale, respectively. Children considered as having developmental delay were invited to attend a genetic evaluation. Results At 4 years of age, the prevalence of ID was 4.5%, and the etiology was classified into 5 groups: environmental (44.4%), genetic (20.5%), idiopathic (12.6%), neonatal sequelae (13.2%), other diseases (9.3%). Most children presented impairment in two or more areas of adaptive behavior. There was no difference in prenatal care attendance or maternal schooling among the groups. Conclusion For about 40% of children, ID was attributed to nonbiological factors, suggesting that the rate may be reduced with appropriate interventions early in life. PMID:27595410

  16. Bullying behaviors among Chinese school-aged youth: a prevalence and correlates study in Guangdong Province.

    Science.gov (United States)

    Wu, Jie; He, Yuan; Lu, Ciyong; Deng, Xueqing; Gao, Xue; Guo, Lan; Wu, Hong; Chan, Fanfan; Zhou, Ying

    2015-02-28

    Bullying among school-aged youth is a common issue worldwide and is increasingly being recognized as an important problem affecting both victims and perpetrators. Most of the bullying studies have been conducted in western countries, and their implications in other regions are limited due to different cultural contexts. The goal of our study is to identify the prevalence of bullying and its correlates school-aged youth in Guangdong province. In total, 1098 (7.1%) students reported having bullied other students, 744 (4.8%) students reported having been bullied by other students and 396 (2.6%) students reported having both bullied other students and been bullied by other students. There was a strong association between bullying others as well as being bullied and suicidal ideations, suicidal attempts, and self-harm behaviors. The prevalence of bullying and its associations with delinquent behaviors warrant the importance of school facility based preventive intervention taking into account both victims and perpetrators. PMID:25510905

  17. Post eclosion age predicts the prevalence of midgut trypanosome infections in Glossina.

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    Deirdre P Walshe

    Full Text Available The teneral phenomenon, as observed in Glossina sp., refers to the increased susceptibility of the fly to trypanosome infection when the first bloodmeal taken is trypanosome-infected. In recent years, the term teneral has gradually become synonymous with unfed, and thus fails to consider the age of the newly emerged fly at the time the first bloodmeal is taken. Furthermore, conflicting evidence exists of the effect of the age of the teneral fly post eclosion when it is given the infected first bloodmeal in determining the infection prevalence. This study demonstrates that it is not the feeding history of the fly but rather the age (hours after eclosion of the fly from the puparium of the fly when it takes the first (infective bloodmeal that determines the level of fly susceptibility to trypanosome infection. We examine this phenomenon in male and female flies from two distinct tsetse clades (Glossina morsitans morsitans and Glossina palpalis palpalis infected with two salivarian trypanosome species, Trypanosoma (Trypanozoon brucei brucei and Trypanosoma (Nannomonas congolense using Fisher's exact test to examine differences in infection rates. Teneral tsetse aged less than 24 hours post-eclosion (h.p.e. are twice as susceptible to trypanosome infection as flies aged 48 h.p.e. This trend is conserved across sex, vector clade and parasite species. The life cycle stage of the parasite fed to the fly (mammalian versus insect form trypanosomes does not alter this age-related bias in infection. Reducing the numbers of parasites fed to 48 h.p.e., but not to 24 h.p.e. flies, increases teneral refractoriness. The importance of this phenomenon in disease biology in the field as well as the necessity of employing flies of consistent age in laboratory-based infection studies is discussed.

  18. Prevalence of missing and impacted third molars in adults aged 25 years and above

    Energy Technology Data Exchange (ETDEWEB)

    Jung, Yun Hoa; Cho, Bong Hae [Dept. of Oral and Maxillofacial Radiology, School of Dentistry, Pusan National University, Yansan (Korea, Republic of)

    2013-12-15

    The purpose of this study was to determine the prevalence of missing and impacted third molars in people aged 25 years and above. The study sample of 3,799 patients was chosen randomly from patients who visited Pusan National University Dental Hospital and had panoramic radiographs taken. The data collected included presence and impaction state, angulation, and depth of impaction of third molars, and radiographically detected lesions of third molars and adjacent second molars. A greater percentage of men than women retained at least one third molar. The incidence of third molars decreased with increasing age. The incidence of partially impacted third molars greatly declined after the age of 30. Vertically impacted maxillary third molars and horizontally impacted mandibular third molars were most frequent in all age groups. Among the maxillary third molars, those impacted below the cervical line of the second molar were most frequent in all age groups, and among the mandibular third molars, deeply impacted third molars were most frequent in those aged over 40. Dental caries was the most common radiographic lesion of the third molars. Mesioangularly impacted third molars showed radiographic lesions in 13 (9.5%) adjacent maxillary second molars and 117 (27.4%) mandibular second molars. The number of remaining third molars decreased and the percentage of Class C depth increased with age. Caries was the most frequent lesion in third molars. Partially impacted mesioangular third molars showed a high incidence of caries or periodontal bone loss of the adjacent second molar. Regular oral examination will be essential to keep asymptomatic third molars in good health.

  19. Mathematical model of mean age, mean arsenic dietary dose and age-specific prevalence rate from endemic chronic arsenic poisoning: a human toxicology study

    Energy Technology Data Exchange (ETDEWEB)

    Zald' ivar, R.; Ghai, G.L.

    1980-01-01

    The aim of this investigation was to develop a mathematical model of mean age, mean arsenic dietary dose, and age-specific prevalence rate for endemic chronic arsenic poisoning. Data on mean age (years), mean arsenic dietary dose (mg/kg body weight/day), and age-specific prevalence rate per 100,000 population for endemic chronic arsenic poisoning in Antofagasta Commune, northern Chile, for the 1968 to 1971 period, were collected. Endemic chronic arsenic poisoning means here chronic arsenical dermatosis associated with marked or sever symptoms (or signs) of chronic arsenic poisoning (chronic diarrhea, hepatic cirrohsis, chronic bronchitis, bronchiectasis, recurrent broncho-pneumonia, cardiomegaly, systemic occlusive arterial disease, cerebral thrombosis, etc.). There was a strong positive correlation between age-specific pevalence rate per 100,000 population and mean arsenic dose (r = + 0.9593) and a negative correlation between prevalence rate and mean age (r = 0.8789). These findings show that the prevalence rate declines with the advancing age and increases with the increase of arsenic dose. A multiple linear regression model E(y) = alpha + beta X1 + gamma X2, where y represents the age-specific prevalence rate per 100,000 population, X1 the mean arsenic dose, and X2 the mean age, was fitted to the data. The estimates of the parameters (alpha, beta, and gamma) were obtained by minimizing the residual sum of squares sigma(y - alpha - beta X1 - gamma X2)2. The following multiple linear regression equation was obtained: Y = 202.161 + 8452.455 X1 - 2.394 X2. Of the total variability in the prevalence rate, 96.22 percent was accounted for by the multiple regression.

  20. Prevalence of somatoform disorders and medically unexplained symptoms in old age populations in comparison with younger age groups : A systematic review

    NARCIS (Netherlands)

    Hilderink, P. H.; Collard, R.; Rosmalen, J. G. M.; Voshaar, R. C. Oude

    2013-01-01

    Objective: To review current knowledge regarding the prevalence of somatization problems in later life by level of caseness (somatoform disorders and medically unexplained symptoms, MUS) and to compare these rates with those in middle-aged and younger age groups. Method: A systematic search of the l

  1. Prevalence of dominant mutations in Spain: effect of changes in maternal age distribution.

    Science.gov (United States)

    Martínez-Frías, M L; Herranz, I; Salvador, J; Prieto, L; Ramos-Arroyo, M A; Rodríguez-Pinilla, E; Cordero, J F

    1988-12-01

    We studied the birth prevalence of autosomal dominant mutations in Spain and estimated how a decrease in maternal age distribution may lead to reduction in dominant mutations. The data were collected by the Estudio Colaborativo Español de Malformaciones Congénitas from April, 1976, to December, 1985. Among 553,270 liveborn infants monitored during the period, 66 infants with autosomal dominant conditions were identified. These included Apert, Crouzon, Hay-Wells, Treacher-Collins, Robinow, Stickler, Adams-Oliver, and the blepharophimosis syndromes, achondroplasia, cleidocranial dysostosis, and thanatophoric dysplasia. The overall rate of autosomal dominant conditions was 1.2 per 10,000 liveborn infants. Thirteen (20%) had an affected relative, and 52 (79%) had a negative family history. One case was excluded because of insufficient family data. The rate of autosomal dominant mutations was 0.9 per 10,000 liveborn infants, or 47 per 1 million gametes. A reduction in the maternal age distribution of mothers age 35 years and older from the current 10.8% to 4.9%, as in Atlanta, Georgia, would reduce the rate of Down syndrome in Spain by 33% and through a change in parternal age distribution may lead to a reduction in dominant mutations of about 9.6%. This suggests that a public health campaign to reduce older maternal age distribution in Spain may also lead to a reduction in dominant mutations and emphasizes the potential that a direct campaign for fathers to complete their families before age 35 years may have a small, but measurable, effect in the primary prevention of dominant mutations.

  2. Prevalence of vitamin D inadequacy in European women aged over 80 years.

    Science.gov (United States)

    Bruyère, Olivier; Slomian, Justine; Beaudart, Charlotte; Buckinx, Fanny; Cavalier, Etienne; Gillain, Sophie; Petermans, Jean; Reginster, Jean-Yves

    2014-01-01

    Inadequate vitamin D status is associated with secondary hyperparathyroidism and increased bone turnover and bone loss, which in turn increases fracture risk. The objective of this study is to assess the prevalence of inadequate vitamin D status in European women aged over 80 years. Assessments of serum 25-hydroxyvitamin D levels (25(OH)D) were performed on 8532 European women with osteoporosis or osteopenia of which 1984 were aged over 80 years. European countries included in the study were: France, Belgium, Denmark, Italy, Poland, Hungary, United Kingdom, Spain and Germany. Two cut-offs of 25(OH)D inadequacy were fixed: nmol/L (30 ng/ml) and nmol/L (20 ng/ml). Mean (SD) age of the patients was 83.4 (2.9) years, body mass index was 25.0 (4.0) kg/m(2) and level of 25(OH)D was 53.3 (26.7) nmol/L (21.4 [10.7] ng/ml). There was a highly significant difference of 25(OH)D level across European countries (pnmol/L, respectively. In the 397 (20.0%) patients taking supplemental vitamin D with or without supplemental calcium, the mean serum 25(OH)D level was significantly higher than in the other patients (65.2 (29.2) nmol/L vs. 50.3 (25.2) nmol/L; Pvitamin D (25(OH)D) inadequacy in old European women. The prevalence could be even higher in some particular countries. PMID:24784761

  3. Estruturas de covariância de peso em função da idade de animais Nelore das regiões Sudeste e Centro-Oeste do Brasil Covariance structure of body weight in function of age for Nellore animals from Southeast and Center West of Brazil

    Directory of Open Access Journals (Sweden)

    B.D. Valente

    2008-04-01

    Full Text Available Dados de peso de animais da raça Nelore de 90 a 450 dias de idade das regiões Sudeste (SE e Centro-Oeste (CO do Brasil foram utilizados para comparar estruturas de (covariância de efeitos aleatórios em função de idade estimadas para as duas regiões por meio de modelos de regressão aleatória. Componentes de (covariância referentes aos coeficientes de regressão aleatória foram estimados por EMREML por meio do programa REMLF90. Os efeitos fixos de grupo contemporâneo e os efeitos aleatórios genético aditivo direto, genético aditivo materno e permanente de ambiente foram modelados por polinômios quadráticos de Legendre. As comparações envolveram estruturas de covariância e de correlação dos efeitos aleatórios, herdabilidades direta e materna e a razão entre variâncias genéticas de diferentes regiões. As herdabilidades e estruturas de covariância e de correlação apresentaram comportamento semelhante nas duas regiões. A variância residual e as variâncias de efeito permanente de ambiente foram menores no CO, bem como a variância genética aditiva materna dos 150 aos 400 dias de idade. Trajetórias dos efeitos fixos em função de idade de diferentes grupos contemporâneos apresentaram diferentes formas, sugerindo a necessidade de estimar um conjunto de coeficientes de regressão específico para cada grupo contemporâneo. A variância do efeito genético aditivo materno apresentou maior heterogeneidade entre regiões do que a variância genética aditiva direta.Body weight records from 90 to 450 days of age of Nellore animals from the Southeast and Center West of Brazil were used do estimate covariance structures of age dependent random effects for each region using random regression models. Covariance components of the regression coefficients were estimated by EMREML using the software REML90. The fixed effects of contemporary groups and additive genetic, additive maternal and permanent environment random effects

  4. Prevalence, Type, Distribution, and Severity of Cerebral Palsy in Relation to Gestational Age: A Meta-Analytic Review

    Science.gov (United States)

    Himpens, E.; Van den Broeck, C.; Oostra, A.; Calders, P.; Vanhaesebrouck, P.

    2008-01-01

    The aim of this review is to determine the relationship between gestational age (GA) and prevalence, type, distribution, and severity of cerebral palsy (CP). Epidemiological studies with cohorts expressed by GA were assessed. A comprehensive meta-analysis and meta-regression was performed on four fetal age categories. Studies of children with CP…

  5. Prevalence of hormone replacement therapy in a sample of middle-aged women

    DEFF Research Database (Denmark)

    Pedersen, S H; Jeune, B

    1988-01-01

    A survey based on a postal questionnaire sent to a random sample of Danish women aged 40-59 yr living on the island of Fünen (n = 401, response rate = 79%) revealed that the overall prevalence of the use of hormone replacement therapy (HRT) was 16%, the highest rate being in the 50-54 age group (21......%). Among post-menopausal women the rate was 21% and it was highest of all (37%) in those who had undergone an artificial menopause. The median age at the start of treatment was 44.3 yr among the artificial menopause and 48.9 yr among the natural menopause subjects. About half of the women were treated...... with natural oestrogen alone and over a third with cyclic natural oestrogen in combination with progestogens. Almost one-third of the women had consulted their doctor about climacteric complaints and two-thirds of these were current or past users of HRT. The women had ambiguous feelings towards HRT...

  6. Prevalence and factors associated with preoperative anxiety in children aged 5-12 years

    Directory of Open Access Journals (Sweden)

    Louise Amália de Moura

    2016-01-01

    Full Text Available Abstract Objective: to estimate the prevalence and factors associated with preoperative anxiety in children who wait for outpatient surgery. Method: cross-sectional analysis of baseline data of a prospective cohort study that investigates the predictors of postoperative pain in children aged 5-12 years submitted to inguinal and umbilical hernia repair. It was selected 210 children, which were interviewed in the preoperative holding area of a general hospital. Anxiety was evaluated using the modified Yale Preoperative Anxiety Scale (mYPAS. Sociodemographic and clinical variables were analyzed as exposure and anxiety (mYPAS final score>30 as outcome. Logistic regression was used to identify factors associated with preoperative anxiety. Results: forty-two percent (42.0% of children presented preoperative anxiety (CI95%: 35.7%-48.6%, with mean scores equal to 30.1 (SD=8.4. Factors associated with preoperative anxiety were: age group of 5-6 years (OR=2.28; p=0.007 and socioeconomic status classified as class C (OR=2.39; p=0.016. Conclusion: the evaluation of children who wait for outpatient surgery should be multidimensional and comprise information on age and socioeconomic status, in order to help in the identification and early treatment of preoperative anxiety.

  7. Prevalence and factors associated with preoperative anxiety in children aged 5-12 years 1

    Science.gov (United States)

    de Moura, Louise Amália; Dias, Iohanna Maria Guimarães; Pereira, Lilian Varanda

    2016-01-01

    Abstract Objective: to estimate the prevalence and factors associated with preoperative anxiety in children who wait for outpatient surgery. Method: cross-sectional analysis of baseline data of a prospective cohort study that investigates the predictors of postoperative pain in children aged 5-12 years submitted to inguinal and umbilical hernia repair. It was selected 210 children, which were interviewed in the preoperative holding area of a general hospital. Anxiety was evaluated using the modified Yale Preoperative Anxiety Scale (mYPAS). Sociodemographic and clinical variables were analyzed as exposure and anxiety (mYPAS final score>30) as outcome. Logistic regression was used to identify factors associated with preoperative anxiety. Results: forty-two percent (42.0%) of children presented preoperative anxiety (CI95%: 35.7%-48.6%), with mean scores equal to 30.1 (SD=8.4). Factors associated with preoperative anxiety were: age group of 5-6 years (OR=2.28; p=0.007) and socioeconomic status classified as class C (OR=2.39; p=0.016). Conclusion: the evaluation of children who wait for outpatient surgery should be multidimensional and comprise information on age and socioeconomic status, in order to help in the identification and early treatment of preoperative anxiety. PMID:27305179

  8. Prevalence of Preventable Causes of Low Vision in Different Ages and Genders

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    Mohsen Akhgary

    2014-01-01

    Full Text Available Background: Much of the vision loss from age-related eye disease can be prevented. The purpose of this study is to determine 5Tthe prevalence5T 5Tof preventable5T 5Tcauses5T 5Tof low5T 5Tvision. Materials and Methods: In this study, files of 204 patients were evaluated5T.5T Low vision was defined as best-corrected visual acuity in the better eye between 20/70 to 20/200. Diagnosis of anterior and posterior segment disease was based on the eye examination that performed with Topcon slit-lamp biomicroscope and direct and indirect ophthalmoscope examination7T. Results: The prevalence of 5Tpreventable5T 5Tcauses of5T 5Tlow 5Twas respectively:5T diabetic retinopathy,5T 5Tin 335T 5Tpatients (5T16.18%, 5Tglaucoma 5Tin 6 5Tpatients (5T2.94%, 5Tand amblyopia5T in 5T2 patients (1%5T. Conclusion: The majority of cases have treatable and/or preventable causes; reduction of low vision or blindness can be achieved by appropriate screening strategies.

  9. Prevalence of oral habits in 563 Nigerian preschool children age 3-5 years.

    Science.gov (United States)

    Onyeaso, C O; Sote, E O

    2001-12-01

    One of the contributory factors in the establishment of occlusion is the child's oral habits. A limited amount of information is available on oral habits of pre-school children especially on Nigerian pre-school children. With an increasing interest in the early recognition of mal-occlusion and a corresponding emphasis on preventive procedures, more information on pre-school children may prove to be useful. This study revealed the prevalence of oral habits among 563 Nigerian pre-school children aged 3-5 years at 13.14%: 6.74% for males, 6.4%for females. The acquired data were tested with chi-square(chi2). The results indicate significant gender difference for tongue thrusting/sucking only (P=0.01) using the fisher's exact test. The relationship between digital sucking habit and mal-occlusion was very significant (P<0.01).

  10. The prevalences of impaired fasting glucose and diabetes mellitus in working age men of North China: Anshan Worker Health Survey.

    Science.gov (United States)

    Liu, Lei; Zhou, Chuang; Du, Hang; Zhang, Kai; Huang, Desheng; Wu, Jingyang

    2014-01-01

    To investigate the prevalence of impaired fasting glucose (IFG) and total diabetes mellitus (DM) including known diabetes and newly diagnosed diabetes in working age men of North China. A cross-section study was conducted at health medical center of Ansteel Group Hospital in Anshan city of China. 37,345 males between 20-60 years of age were recruited in this study. Age-standardized prevalence of IFG and total DM in these working age men were 25.3% and 8.4%, respectively. The prevalence of IFG and total DM increased, as the age progressed. After multinomial logit analysis, age, systolic blood pressure, drinking, smoking, overweight and obesity, total cholesterol, triglycerides, serum creatinine and blood urea nitrogen were independent risk factors for both IFG and DM. The prevalence rate of IFG in Anshan male workers was higher compared with mainland China overall. Diabetes-related education and popularization of DM prevention programs should be actively carried out with age increasing. PMID:24824525

  11. Periodontitis prevalence in adults ≥ 65 years of age, in the USA.

    Science.gov (United States)

    Eke, Paul I; Wei, Liang; Borgnakke, Wenche S; Thornton-Evans, Gina; Zhang, Xingyou; Lu, Hua; McGuire, Lisa C; Genco, Robert J

    2016-10-01

    The older adult population is growing rapidly in the USA and it is expected that by 2040 the number of adults ≥ 65 years of age will have increased by about 50%. With the growth of this subpopulation, oral health status, and periodontal status in particular, becomes important in the quest to maintain an adequate quality of life. Poor oral health can have a major impact, leading to tooth loss, pain and discomfort, and may prevent older adults from chewing food properly, often leading to poor nutrition. Periodontitis is monitored in the USA at the national level as part of the Healthy People 2020 initiative. In this report, we provide estimates of the overall burden of periodontitis among adults ≥ 65 years of age and after stratification according to sociodemographic factors, modifiable risk factors (such as smoking status), the presence of other systemic conditions (such as diabetes) and access to dental care. We also estimated the burden of periodontitis within this age group at the state and local levels. Data from the National Health and Nutrition Examination Survey 2009/2010 and 2011/2012 cycles were analyzed. Periodontal measures from both survey cycles were based on a full-mouth periodontal examination. Nineteen per cent of adults in this subpopulation were edentulous. The mean age was 73 years, 7% were current smokers, 8% lived below the 100% Federal Poverty Level and periodontitis in Utah (62.3%) and New Hampshire (62.6%) and the highest in New Mexico, Hawaii, and the District of Columbia each with a prevalence of higher than 70%. Overall, periodontitis is highly prevalent in this subpopulation, with two-thirds of dentate older adults affected at any geographic level. These findings provide an opportunity to determine how the overall health-care management of older adults should consider the improvement of their oral health conditions. Many older adults do not have dental insurance and are also likely to have some chronic conditions, which can

  12. Socioeconomic status and the prevalence of fever in children under age five: evidence from four sub-Saharan African countries

    OpenAIRE

    Novignon Jacob; Nonvignon Justice

    2012-01-01

    Abstract Background The burden of fevers remains enormous in sub-Saharan Africa. While several efforts at reducing the burden of fevers have been made at the macro level, the relationship between socioeconomic status and fever prevalence has been inconclusive at the household and individual levels. The purpose of this study was to examine how individual and household socioeconomic status influences the prevalence of fever among children under age five in four sub-Saharan African countries. Me...

  13. Prevalence of Cognitive Impairment and Depression among a Population Aged over 60 Years in the Metropolitan Area of Guadalajara, Mexico

    OpenAIRE

    Ortiz, Genaro G.; Arias-Merino, Elva D.; Flores-Saiffe, María E.; Velázquez-Brizuela, Irma E.; Macías-Islas, Miguel A.; Fermín P. Pacheco-Moisés

    2012-01-01

    Background. Cognitive impairment is an important clinical issue among elderly patients with depression and has a more complex etiology because of the variable rate of neurodegenerative changes associated with depression. The aim of the present work was to examine the prevalence of cognitive impairment and depression in a representative sample of adults aged ≥60 years. Methods. The presented work was a cross-sectional study on the prevalence of cognitive impairment and depression. Door-to-doo...

  14. Low prevalence of contraceptive counseling at Srinagarind hospital, Thailand among women of reproductive age with systemic lupus erythematosus

    OpenAIRE

    Kittisiam, Thannaporn; Werawatakul, Yuthapong; Nanagara, Ratanavadee; Wantha, Orathai

    2013-01-01

    Objective Unplanned pregnancy in women with SLE can have grave complications both for the child and the woman. We studied the prevalence of contraceptive counseling among women of reproductive age with SLE at a university hospital in Northeast Thailand. Methods Recruited: 125 women with SLE, between 15 and 50 years, followed up at the Rheumatology Clinic. A questionnaire was administered and the results analyzed to identify the prevalence of contraceptive counseling. Results The majority of w...

  15. Differences in Oral Sexual Behaviors by Gender, Age, and Race Explain Observed Differences in Prevalence of Oral Human Papillomavirus Infection

    OpenAIRE

    Gypsyamber D'Souza; Kevin Cullen; Janice Bowie; Roland Thorpe; Carole Fakhry

    2014-01-01

    PURPOSE: This study explores whether gender, age and race differences in oral sexual behavior account for the demographic distribution of oral human papillomavirus infection (HPV) and HPV-positive oropharyngeal cancer (HPV-OSCC). METHODS: This analysis included 2,116 men and 2,140 women from NHANES (2009-10) who answered a behavioral questionnaire and provided an oral-rinse sample for HPV detection. Weighted prevalence estimates and prevalence ratios (PR) were calculated for sexual behaviors ...

  16. Increase in malaria prevalence and age of at risk population in different areas of Gabon

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    Mawili-Mboumba Denise P

    2013-01-01

    Full Text Available Abstract Background Following the deployment of new recommendations for malaria control according to the World Health Organization, an estimation of the real burden of the disease is needed to better identify populations at risk and to adapt control strategies. The aim of the present study was to estimate the clinical burden of malaria among febrile children aged less than 11 years, before and after six-year of deployment of malaria control strategies in different areas of Gabon. Methods Cross-sectional surveys were carried out in health care facilities at four locations: two urban areas (Libreville and Port-Gentil, one semi-urban area (Melen and one rural area (Oyem, between 2005 and 2011. Febrile paediatric patients, aged less than 11 years old were screened for malaria using microscopy. Body temperature, history of fever, age, sex, and location were collected. Results A total of 16,831 febrile children were enrolled; 78.5% (n=13,212 were less than five years old. The rate of Plasmodium falciparum-infection was the lowest in Port-gentil (below 10% and the highest at Oyem (above 35%. Between 2005 and 2008, malaria prevalence dropped significantly from 31.2% to 18.3%, followed by an increase in 2011 in Libreville (24.1%, Port-Gentil (6.5% and Oyem (44.2% (ppp0.01. The risk of being P. falciparum-infected in children aged less than five years old significantly decreased from 2008 to 2011 (p Conclusions This study shows an increased risk of malaria infection in different areas of Gabon with over-five year-old children tending to become the most at-risk population, suggesting a changing epidemiology. Moreover, the heterogeneity of the malaria burden in the country highlights the importance of maintaining various malaria control strategies and redefining their implementation.

  17. Prevalence of thinness among the adolescent girls (age group 13yrs-18yrs of Garhkhal village of Himachal Pradesh, India.

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    Priyanka Rani Garg

    2011-08-01

    Full Text Available Malnutrition has now been redefined in terms of “under nutrition” and conceptualized in terms of thinness which is an important problem among children and adolescents in rural areas of developing countries like India. Therefore, present study was carried out to assess the prevalence of thinness among the adolescent girls (age group 13yrs-18yrs of Garhkhal Village of Himachal Pradesh, India. The study design was cross-sectional. Height and weight were measured and Body Mass Index (BMI was carried out. Identification of thinness was done according to the new International BMI-based classification cut offs as given by Cole et al., 2007. In general the mean BMI increased with increasing age. Overall age-combined prevalence was 79.5%. Present study indicated the poor health status of the adolescent girls of the selected area which indicates the high nutritional stress among them as evident from the thinness prevalent among them.

  18. [Prevalence of deficiency and dietary intake of iron, zinc and copper in Chilean childbearing age women].

    Science.gov (United States)

    Mujica-Coopman, María F; Borja, Angélica; Pizarro, Fernando; Olivares, Manuel

    2014-03-01

    The aim of the present study was to evaluate anemia, the biochemical status and dietary adequacy of iron (Fe), zinc (Zn) and copper (Cu), in Chilean childbearing age women. We studied a convenience sample of 86 women aged 18 to 48 years from Santiago, Chile. We determined anemia and the micronutrient status through hemoglobin (Hb) mean corpuscular volume, transferrin saturation, zinc protoporphyrin, serum ferritin (SF), serum Zn and Cu. Dietary adequacy was estimated using a food frequency questionnaire. Of all women, 4.7% had Fe deficiency (ID) anemia, 21 % ID without anemia, 26 % depleted Fe stores and 48.3% normal Fe status. Obese women had higher SF (p<0.01) compared with those classified as having normal BMI. Also, showed higher Hb (p<0.05) concentrations compared with overweight and normal weight women. Partidipants showed 3.5 % and 2.3 % of Zn and Cu deficiency, respectively. Also, 95 %, 94 % and 99 % had adequate intake of Fe, Zn and Cu respectively, according to EAR cut points. There were no significant differences in micronutrients intake across different nutritional status. There was a low prevalence of anemia, Fe, Zn and Cu deficiency. A high percentage of women reached micronutrient adequacy. However, 47% of women had ID without anemia and Fe depleted stores.

  19. Chronic cerebrospinal venous insufficiency in multiple sclerosis: a highly prevalent age-dependent phenomenon

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    Lanzillo Roberta

    2013-02-01

    Full Text Available Abstract Background This study aimed to investigate the prevalence and clinical relevance of chronic cerebrospinal venous insufficiency (CCSVI in multiple sclerosis (MS patients and healthy controls using extra- and intracranial colour Doppler sonography. Methods We examined 146 MS patients, presenting with a clinically isolated syndrome, relapsing-remitting, secondary progressive, or primary progressive MS, and 38 healthy controls. Sonographic examination was performed according to Zamboni’s protocol and was performed by three independent sonographers. The results of sonographic examination were compared with clinical and demographic characteristics of the patients. Results CCSVI, defined as the presence of at least two positive Zamboni’s criteria, was found in 76% of MS patients and 16% of control subjects. B-mode anomalies of internal jugular veins, such as stenosis, malformed valves, annuli, and septa were the most common lesions detected in MS patients (80.8% and controls (47.4%. We observed a positive correlation between sonographic diagnosis of CCSVI and the patients’ age (p = 0.003. However, such a correlation was not found in controls (p = 0.635. Notably, no significant correlations were found between sonographic signs of CCSVI and clinical characteristics of MS, except for absent flow in the jugular veins, which was found more often in primary (p Conclusions Sonographically defined CCSVI is common in MS patients. However, CCSVI appears to be primarily associated with the patient’s age, and poorly correlated with the clinical course of the disease.

  20. Prevalence of Anemia and Associated Factors in Child Bearing Age Women in Riyadh, Saudi Arabia

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    AlJohara M. AlQuaiz

    2013-01-01

    Full Text Available Objective. To determine the prevalence and risk factors for anemia in child bearing age women in Riyadh, Saudi Arabia. Design. Cross-sectional survey was conducted using two-stage cluster sampling. 25 clusters (primary health care centers (PHCC were identified from all over Riyadh, and 45–50 households were randomly selected from each cluster. Eligible women were invited to PHCC for questionnaire filling, anthropometric measurements, and complete blood count. Blood hemoglobin was measured with Coulter Cellular Analysis System using light scatter method. Setting. PHCC. Subjects. 969 (68% women out of 1429 women were included in the analysis. Results. Mean hemoglobin was 12.35 (±1.80 g/dL, 95% CI 12.24–12.46 with interquartile range of 1.9. Anemia (Hb <12 g/dL was present in 40% (390 women. Mean (±SD for MCH, MCV, MCHC, and RDW was 79.21 (±12.17 fL, 26.37 (±6.21 pg, 32.36 (±4.91 g/dL, and 14.84 (±4.65%, respectively. Multivariate logistic regression revealed that having family history of iron deficiency anemia (OR 2.91, 95% CI 1.78–4.76 and infrequent intake of meat (OR 1.54, 95%CI 1.15–2.05 were associated with increased risk of anemia, whereas increasing body mass index (OR 0.95, 95% CI 0.92–0.97 was associated with reduced risk of anemia. Conclusion. Women should be educated about proper diet and reproductive issues in order to reduce the prevalence of anemia in Saudi Arabia.

  1. Auto covariance computer

    Science.gov (United States)

    Hepner, T. E.; Meyers, J. F. (Inventor)

    1985-01-01

    A laser velocimeter covariance processor which calculates the auto covariance and cross covariance functions for a turbulent flow field based on Poisson sampled measurements in time from a laser velocimeter is described. The device will process a block of data that is up to 4096 data points in length and return a 512 point covariance function with 48-bit resolution along with a 512 point histogram of the interarrival times which is used to normalize the covariance function. The device is designed to interface and be controlled by a minicomputer from which the data is received and the results returned. A typical 4096 point computation takes approximately 1.5 seconds to receive the data, compute the covariance function, and return the results to the computer.

  2. Prevalence and associated factors of contraceptive discontinuation and switching among Bangladeshi married women of reproductive age

    Directory of Open Access Journals (Sweden)

    Mahumud RA

    2015-01-01

    Full Text Available Rashidul Alam Mahumud,1 Md Golam Hossain,2 Abdur Razzaque Sarkar,1 Md Nurul Islam,2 Md Ripter Hossain,2 Aik Saw,3 Jahangir AM Khan1,4 1Health Economics and Financing Research Group, Center for Equity and Health Systems, International Centre for Diarrhoeal Disease Research, Bangladesh, Dhaka, Bangladesh; 2Department of Statistics, University of Rajshahi, Rajshahi, Bangladesh; 3Department of Orthopaedic Surgery, National Orthopaedic Centre of Excellence for Research and Learning, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia; 4Adjunct Faculty, Health Economics Unit, Department of Learning, Informatics, Management and Ethics, Karolinska Institutet, Stockholm, Sweden Introduction: Contraceptive discontinuation is a worldwide incident that may be connected with low incentive to avoid pregnancy. Contraceptive discontinuation highly contributes to unplanned pregnancy and unwanted births.Objectives: The objective of this study was to observe the prevalence of discontinuation and switching of contraceptive methods among Bangladeshi married women. In addition, the sociodemographic factors associated with contraceptive discontinuation and switching were assessed.Methods: Secondary cross-sectional data was used in this study. A total of 16,273 married Bangladeshi women of reproductive age (15–49 years were considered in the present study, from the Bangladesh Demographic and Health Survey, 2011. Logistic regression models were used to determine the relationships between key sociodemographic factors and user status.Results: The prevalence of discontinuation and switching of contraceptive method among women were 38.4% and 15.4%, respectively. The logistic regression model demonstrated that women in early reproductive years (25–29 years and 30–34 years significantly more often (odds ratio [OR] =0.84 and 0.71, respectively discontinued use of contraceptives. Significantly higher rates of discontinuation were pronounced among women who

  3. High age-adjusted prevalence of Parkinson's disease among Inuits in Greenland

    DEFF Research Database (Denmark)

    Wermuth, Lene; Pakkenberg, Henning; Jeune, Bernard

    2002-01-01

    The prevalence of PD among Inuits in Greenland has not been determined. The authors found 40 patients with PD at the prevalence date January 1, 2000. The crude prevalence of PD was estimated to be 81.0 per 100.000 inhabitants born in Greenland. However, owing to the low proportion of 50+ year old...

  4. Brownian distance covariance

    OpenAIRE

    Székely, Gábor J.; Rizzo, Maria L.

    2009-01-01

    Distance correlation is a new class of multivariate dependence coefficients applicable to random vectors of arbitrary and not necessarily equal dimension. Distance covariance and distance correlation are analogous to product-moment covariance and correlation, but generalize and extend these classical bivariate measures of dependence. Distance correlation characterizes independence: it is zero if and only if the random vectors are independent. The notion of covariance with respect to a stochas...

  5. Prevalence, and Intellectual Outcome of Unilateral Focal Cortical Brain Damage as a Function of Age, Sex and Aetiology

    Directory of Open Access Journals (Sweden)

    C. M. J. Braun

    2002-01-01

    Full Text Available Neurologists and neuropsychologists are aware that aging men are more at risk than women for brain damage, principally because of the well known male-predominant risk for cardiovascular disease and related cerebrovascular accidents. However, a disproportion in prevalence of brain damage between the sexes in childhood may be less suspected. Furthermore, sex-specific risk for other aetiologies of brain damage may be little known, whether in the pediatric or adult populations. Proposals of a sex difference in cognitive recovery from brain damage have also been controversial. Six hundred and thirty five “consecutive” cases with cortical focal lesions including cases of all ages and both sexes were reviewed. Aetiology of the lesion was determined for each case as was postlesion IQ. Risk was highly male prevalent in all age groups, with a predominance of cardiovascular aetiology explaining much of the adult male prevalence. However, several other aetiological categories were significantly male prevalent in juveniles (mitotic, traumatic, dysplasic and adults (mitotic, traumatic. There was no sex difference in outcome (i.e., postlesion IQ of these cortical brain lesions for the cohort as a whole, after statistical removal of the influence of lesion extent, aetiology and presence of epilepsy. Mechanisms potentially responsible for sex differences in prevalence, aetiology of brain damage, and recovery, are reviewed and discussed.

  6. Prevalence of Cardiovascular Risk Factors in the Middle-Aged and Elderly Population of a Nigerian Rural Community

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    E. C. Ejim

    2011-01-01

    Full Text Available Cardiovascular diseases (CVDs causes of worldwide preventable morbidity and mortality. CVDs are a leading cause of mortality and morbidity in developing countries, and rates are expected to rise over the next few decades. The prevalence of CVD risk factors is dramatically increasing in low-and middle-income African countries, particularly in urban areas. We carried out a cross-sectional population-based survey in Imezi-Owa, a rural community in South East Nigeria to estimate the prevalence of major cardiovascular risk factors in both men and women aged 40–70 years. A total of 858 individuals made up of 247 (28.8% males and 611 (71.2% females were recruited. The mean age of the subjects was 59.8±9.9 years. The prevalence of the different cardiovascular risk factors among the 858 subjects was as follows: hypertension 398 (46.4% subjects, generalized obesity as determined by BMI 257 (30% subjects, abdominal obesity 266 (31% subjects, dysglycaemia 38 (4.4% subjects and hypercholesterolaemia 32 (3.7% subjects. Prevalence of hypertension and dysglycaemia was higher in men while the others were higher in women. Only hypertension (P=.117 and hypercholesterolaemia (P=.183 did not reveal any significant association with gender. Prevalence of CVD risk factors was highest in subjects aged 65 to 70 years.

  7. Prevalence of uncorrected refractive errors in adults aged 30 years and above in a rural population in Pakistan

    International Nuclear Information System (INIS)

    Uncorrected refractive errors are a leading cause of visual disability globally. This population-based study was done to estimate the prevalence of uncorrected refractive errors in adults aged 30 years and above of village Pawakah, Khyber Pakhtunkhwa (KPK), Pakistan. Methods: It was a cross-sectional survey in which 1000 individuals were included randomly. All the individuals were screened for uncorrected refractive errors and those whose visual acuity (VA) was found to be less than 6/6 were refracted. In whom refraction was found to be unsatisfactory (i.e., a best corrected visual acuity of <6/6) further examination was done to establish the cause for the subnormal vision. Results: A total of 917 subjects participated in the survey (response rate 92%). The prevalence of uncorrected refractive errors was found to be 23.97% among males and 20% among females. The prevalence of visually disabling refractive errors was 6.89% in males and 5.71% in females. The prevalence was seen to increase with age, with maximum prevalence in 51-60 years age group. Hypermetropia (10.14%) was found to be the commonest refractive error followed by Myopia (6.00%) and Astigmatism (5.6%). The prevalence of Presbyopia was 57.5% (60.45% in males and 55.23% in females). Poor affordability was the commonest barrier to the use of spectacles, followed by unawareness. Cataract was the commonest reason for impaired vision after refractive correction. The prevalence of blindness was 1.96% (1.53% in males and 2.28% in females) in this community with cataract as the commonest cause. Conclusions: Despite being the most easily avoidable cause of subnormal vision uncorrected refractive errors still account for a major proportion of the burden of decreased vision in this area. Effective measures for the screening and affordable correction of uncorrected refractive errors need to be incorporated into the health care delivery system. (author)

  8. PREVALENCE OF TESTOSTERONE DEFICIENCY IN PATIENTS OF DIABETES MELLITUS LESS THAN 40 YEARS OF AGE

    Directory of Open Access Journals (Sweden)

    Praveen K

    2016-01-01

    Full Text Available BACKGROUND Diabetes mellitus is common endocrine disorder which involves multiple organs and leads to significant morbidity and mortality due to accompanying complications. Erectile dysfunction, reduced libido, orgasmic dysfunction, and retrograde ejaculation are established complications found with variable prevalence in men with diabetes. METHODOLOGY In the present study, total 90 male patients of diabetes mellitus of age below 40 years were taken from medical outpatient department and indoor patients of medical wards of a tertiary care teaching hospital of South Delhi. They were evaluated for complains regarding sexual dysfunction. Hormonal assays of serum free testosterone, LH, FSH, C-peptide, HbA1c and lipid profile were carried out in all patients. RESULT Present study shows that testosterone deficiency is quite common in young diabetic patients. Low serum free testosterone was more common in type 2 diabetes as compared to type 1 diabetes (38.46% Vs 29.41%. BMI has significant effect on serum free testosterone levels. Patients with higher BMI had negative correlation to free testosterone although testosterone deficiency was also seen in few lean patients. High serum triglyceride and low serum HDL were seen more frequently in patients with low free testosterone. CONCLUSION This study reveals that hypogonadism is not a rarity even at initial stages of diabetes. This study, although small, highlights importance of assessment of young diabetic patients for sexual dysfunction and hypogonadism.

  9. Psychiatric disorders and MND in non-handicapped preterm children - Prevalence and stability from school age into adolescence

    NARCIS (Netherlands)

    Schoihorst, P. F.; Swaab-Barneveld, H.; van Engeland, H.

    2007-01-01

    In preterm children (N = 66) without major physical and/or mental handicaps the prevalence of psychiatric disorders and minor neurological dysfunction (MND) was assessed at school age (8-10 years). In adolescence (15-17 years) 43 children were reassessed. The study sample was drawn from a cohort of

  10. Prevalence of metabolic syndrome and obesity in adolescents aged 12 to 19 years: Comparison between the United States and Korea

    Science.gov (United States)

    This study compared the prevalence of metabolic syndrome (MetS), its risk factors, and obesity in adolescents in the United States (US) and Korea. Data were obtained from the 2003-2004 US National Health and Nutrition Examination Survey (NHANES), and 2005 Korea NHANES for adolescents aged 12-19 yr i...

  11. High prevalence of sensitization to aeroallergens in children 4 yrs of age or younger with symptoms of allergic disease

    NARCIS (Netherlands)

    de Jong, Adriana Baatenburg; Dikkeschei, Lambert D.; Brand, Paul L. P.

    2009-01-01

    The assumption that sensitization to aeroallergens is rare in preschool children is based on population studies in which most subjects have little or no symptoms of atopic disease. We assessed the prevalence of atopic sensitization in children 0 to 4 yr of age presenting with symptoms of allergic di

  12. Prevalence of Neutralizing Antibodies to Japanese Encephalitis Virus among High-Risk Age Groups in South Korea, 2010.

    Directory of Open Access Journals (Sweden)

    Eun Ju Lee

    Full Text Available After an extensive vaccination policy, Japanese encephalitis (JE was nearly eliminated since the mid-1980s in South Korea. Vaccination in children shifted the affected age of JE patients from children to adults. However, an abrupt increase in JE cases occurred in 2010, and this trend has continued. The present study aimed to investigate the prevalence of neutralizing antibodies to the JE virus (JEV among high-risk age groups (≥40 years in South Korea. A plaque reduction neutralization test was conducted to evaluate the prevalence of neutralizing antibodies to JEV in 945 subjects within four age groups (30-39, 40-49, 50-59, and 60-69 years in 10 provinces. Of the 945 enrolled subjects, 927 (98.1% exhibited antibodies against JEV. No significant differences were found in the prevalence of neutralizing antibodies according to sex, age, or occupation. However, there were significant differences in the plaque reduction rate according to age and occupation; oldest age group had a higher reduction rate, and subjects who were employed in agriculture or forestry also had a higher value than the other occupations. We also found that three provinces (Gangwon, Jeonnam, and Gyeongnam had a relatively lower plaque reduction rate than the other locations. In addition, enzyme-linked immunosorbent assays were conducted to determine recent viral infections and 12 (1.3% subjects were found to have been recently infected by the virus [corrected]. In conclusion, the present study clearly indicated that the prevalence of neutralizing antibodies has been maintained at very high levels among adult age groups owing to vaccination or natural infections, or both. In the future, serosurveillance should be conducted periodically using more representative samples to better understand the population-level immunity to JE in South Korea.

  13. Prevalence of Cognitive Impairment and Depression among a Population Aged over 60 Years in the Metropolitan Area of Guadalajara, Mexico.

    Science.gov (United States)

    Ortiz, Genaro G; Arias-Merino, Elva D; Flores-Saiffe, María E; Velázquez-Brizuela, Irma E; Macías-Islas, Miguel A; Pacheco-Moisés, Fermín P

    2012-01-01

    Background. Cognitive impairment is an important clinical issue among elderly patients with depression and has a more complex etiology because of the variable rate of neurodegenerative changes associated with depression. The aim of the present work was to examine the prevalence of cognitive impairment and depression in a representative sample of adults aged ≥60 years. Methods. The presented work was a cross-sectional study on the prevalence of cognitive impairment and depression. Door-to-door interview technique was assigned in condition with multistage probability random sampling to obtain subjects that represent a population of the Guadalajara metropolitan area (GMA), Mexico. Cognitive function and depression were assessed by applying standardized Mini-Mental State Examination of Folstein (MMSE) and the Geriatric Depression Scale (GDS), respectively. Results. Prevalence of cognitive impairment was 13.8% (14.5% women, 12.6% men); no significant differences by gender and retired or pensioner were found. Prevalence of depression was 29.1% (33.6% women, 21.1% men); no significant differences by retired or pensioner were found. Cognitive impairment was associated with depression (OR  =  3.26, CI 95%, 2.31-4.60). Prevalence of cognitive impairment and depression is associated with: being woman, only in depression being older than 75 years being married, and a low level of education. Conclusion. Cognitive impairment and depression are highly correlated in adults aged ≥60.

  14. Prevalence of Cognitive Impairment and Depression among a Population Aged over 60 Years in the Metropolitan Area of Guadalajara, Mexico

    Directory of Open Access Journals (Sweden)

    Genaro G. Ortiz

    2012-01-01

    Full Text Available Background. Cognitive impairment is an important clinical issue among elderly patients with depression and has a more complex etiology because of the variable rate of neurodegenerative changes associated with depression. The aim of the present work was to examine the prevalence of cognitive impairment and depression in a representative sample of adults aged ≥60 years. Methods. The presented work was a cross-sectional study on the prevalence of cognitive impairment and depression. Door-to-door interview technique was assigned in condition with multistage probability random sampling to obtain subjects that represent a population of the Guadalajara metropolitan area (GMA, Mexico. Cognitive function and depression were assessed by applying standardized Mini-Mental State Examination of Folstein (MMSE and the Geriatric Depression Scale (GDS, respectively. Results. Prevalence of cognitive impairment was 13.8% (14.5% women, 12.6% men; no significant differences by gender and retired or pensioner were found. Prevalence of depression was 29.1% (33.6% women, 21.1% men; no significant differences by retired or pensioner were found. Cognitive impairment was associated with depression (OR  =  3.26, CI 95%, 2.31–4.60. Prevalence of cognitive impairment and depression is associated with: being woman, only in depression being older than 75 years being married, and a low level of education. Conclusion. Cognitive impairment and depression are highly correlated in adults aged ≥60.

  15. Prevalence of diagnosed and undiagnosed diabetes mellitus in adults aged 19 years and older in Basrah, Iraq

    OpenAIRE

    Mansour AA; Al-Maliky AA; Kasem B; Jabar A; Mosbeh KA

    2014-01-01

    Abbas Ali Mansour, Ahmed A Al-Maliky, Bashar Kasem, Abdulsatar Jabar, Khalid Abdulabass MosbehAl-Faiha Diabetes Endocrine and Metabolism Center (FDEMC) Basrah, IraqBackground: Six of the top ten countries in the world with the highest prevalence of diabetes mellitus are in the Middle East. The objective of this investigation was to evaluate the prevalence of diabetes in Basrah, Southern Iraq.Methods: A population-based, cross-sectional, simple random study screened 5,445 persons aged 19&n...

  16. Stroke Prevalence, Mortality and Disability-Adjusted Life Years in Children and Youth Aged 0-19 Years

    DEFF Research Database (Denmark)

    Krishnamurthi, Rita V; deVeber, Gabrielle; Feigin, Valery L;

    2015-01-01

    increases in the global prevalence rates of childhood IS, as well as significant decreases in the global death rate and DALYs rate of all strokes in those of age 0-19 years. While prevalence rates for childhood IS and HS decreased significantly in developed countries, a decline was seen only in HS...... stroke care. © 2015 S. Karger AG, Basel.......BACKGROUND: There is increasing recognition of stroke as an important contributor to childhood morbidity and mortality. Current estimates of global childhood stroke burden and its temporal trends are sparse. Accurate and up-to-date estimates of childhood stroke burden are important for planning...

  17. Prevalence, topographic and morphometric features of femoral cam-type deformity: changes in relation to age and gender.

    Science.gov (United States)

    Morales-Avalos, R; Leyva-Villegas, J I; Sánchez-Mejorada, G; Reynaga-Obregón, J; Galindo-de León, S; Vílchez-Cavazos, F; Espinosa-Uribe, A G; Acosta-Olivo, C; de la Garza-Castro, O; Guzmán-Avilan, R I; Elizondo-Omaña, R E; Guzmán-López, S

    2016-09-01

    Femoroacetabular impingement (FAI) syndrome is a frequent cause of pain and in recent years considered to be a precursor of premature hip osteoarthritis. The structural abnormalities which characterize FAI syndrome, such as the cam-type deformity, are associated with morphological alterations that may lead to hip osteoarthritis. The aim of this study was to determine the prevalence and topographic and morphometric features of the cam deformity in a series of 326 femur specimens obtained from a Mexican population, as well as changes in prevalence in relation to age and gender. The specimens were subdivided into groups according to gender and age. A standardized photograph of the proximal femur of each specimen was taken, and the photograph was used to determine the alpha angle using a computer program; the location of the lesion was determined by quadrant and the morphometric characteristics were determined by direct observation. The overall prevalence of cam deformities in the femur specimens was 29.8 % (97/326), with a prevalence by gender of 35.2 % (64/182) in men and 22.9 % (33/144) in women. The mean alpha angle was 54.6° ± 8.5° in all of the osteological specimens and 65.6° ± 7.5° in those specimens exhibiting a cam deformity. Cam deformities were found topographically in the anterior-superior quadrant of the femoral head-neck junction in 86.6 % (84/97) of the femurs. Deformities were found in 28.2 % of the right femurs and 31.3 % of the left femurs. The prevalence of cam deformity was higher in the femur specimens of young men and in those of middle-aged and older women. There were no significant differences in this deformity in relation to the alpha angle according to age and gender. PMID:26573638

  18. Age-related changes in prevalence and symptom characteristics in kidney deficiency syndrome with varied health status: a cross-sectional observational study

    Directory of Open Access Journals (Sweden)

    Yin Zhang

    2014-07-01

    Conclusion: Prevalence and symptom characteristics of KDS were found to increase consistently with increasing age and deteriorating health status. Kidney deficiency may be an important mechanism of aging in the subhealthy and chronic disease states.

  19. Prevalence of dental fluorosis in children taking part in an oral health programme including fluoride tablet supplements from the age of 2 years

    DEFF Research Database (Denmark)

    Eckersten, Charlotte; Pylvänen, Lena; Schröder, Ulla;

    2010-01-01

    To investigate the prevalence of dental fluorosis in children who had participated in an oral health programme between the ages 2-5 years, including fluoride tablets from the age of 2 years.......To investigate the prevalence of dental fluorosis in children who had participated in an oral health programme between the ages 2-5 years, including fluoride tablets from the age of 2 years....

  20. Prevalence of diabetes mellitus and affecting factors of diabetes mellitus in adult age group in Van province

    Directory of Open Access Journals (Sweden)

    Hatice Yılmaz

    2011-12-01

    Full Text Available Objectives: Regional studies of diabetes mellitus (DM are important to determine of effective environmental factors in the development of DM and defining strategy against these factors. This study aims to define the frequency of DM prevalence in the province of the Van city, distribution of DM according to age groups, effective socio-economical, geographical and metabolic factors over the diabetes development.Material and methods: This study included 191 male and 209 female totals 400 person aged year 16 years or over. Blood-Glucose levels of persons were measured with Accu-check glucometer and questionnaires were filled with face-to-face interviews.Results: Age mean of subjects was 35.09±13.75 years, DM prevalence was %13.4 between the females and %9.1 males, disglisemi (DG prevalence were %9.1 between the females and %5.8 between the males. 74.4% of impaired glucose metabolism persons were people who they do not make physical exercise and adopted sedentary lifestyle.Conclusion: In this study, age and family history from unchangeable factors were found to be effective on the development of DM but sex, educational level, social security, incomes were not found to be effective on development of DM. Exercise, blood pressure levels, obesity and diets from changeable factors are the factors that influence the frequency of DM was determined in this study. J Clin Exp Invest 2011; 2 (4: 392-399

  1. A seroepidemiologic study of hepatitis A in Spanish children. Relationship of prevalence to age and socio-environmental factors.

    Science.gov (United States)

    Morales, J L; Huber, L; Gallego, S; Alvarez, G; Diez-Delgado, J; González, A; Aguilar, L; Dal-Ré, R

    1992-01-01

    Three child population groups from the Madrid area were studied for anti-HAV antibodies. Analysis was carried out with respect to age and socio-environmental factors. The population understudy was composed of 156 children, with ages ranging from 1 to 14 years; they were stratified in three socio-environmental groups (white-family unit, gypsy-family unit and orphanage), and also divided into subgroups according to age. As a whole, an age-related increase in prevalence was found. The overall seroprevalence by socio-environmental groups was: gypsy-family unit 63%, orphanage 46%, and white-family unit 23%. Significant differences between groups appeared from seven years on, being more marked among the eldest subgroups. Among the factors evaluated, hygienic-sanitary conditions and overcrowding influenced the high prevalence rate found in the gypsy-family unit subjects, whereas overcrowding appeared to be responsible for the higher prevalence in orphanage residents, as compared to white-family unit children.

  2. Prevalence of hypertension among reproductive age group tribal women in Visakhapatnam district, Andhra Pradesh, India

    Directory of Open Access Journals (Sweden)

    S. Appala Naidu

    2016-04-01

    Results: Among the study women, 40.6% belonged to prime tribe groups (PTG and 36% of women had debts. Two fifths (40.7% of tribal women were normotensive and another two fifths (42.1% were in pre-hypertensive stage. Stage-1 hypertension was observed in 16.3% of study women. Non- PTGs and women with debts had significantly high prevalence of hypertension when compared to other groups. Conclusions: Prevalence of HTN was more in tribal women when compared to national prevalence indicating the need of screening of blood pressures in tribal communities. [Int J Res Med Sci 2016; 4(4.000: 1224-1228

  3. Intake of high-fructose corn syrup sweetened soft drinks, fruit drinks and apple juice is associated with prevalent arthritis in US adults, aged 20–30 years

    Science.gov (United States)

    DeChristopher, L R; Uribarri, J; Tucker, K L

    2016-01-01

    Objective: There is a link between joint and gut inflammation of unknown etiology in arthritis. Existing research indicates that regular consumption of high-fructose corn syrup sweetened (HFCS) soft drinks, but not diet soft drinks, may be associated with increased risk of seropositive rheumatoid arthritis (RA) in women, independent of other dietary and lifestyle factors. One unexplored hypothesis for this association is that fructose malabsorption, due to regular consumption of excess free fructose (EFF) and HFCS, contributes to fructose reactivity in the gastrointestinal tract and intestinal in situ formation of enFruAGEs, which once absorbed, travel beyond the intestinal boundaries to other tissues and promote inflammation. In separate studies, the accumulation of advanced glycation end-products has been associated with joint inflammation in RA. Objective of this study was to assess the association between EFF beverages intake and non-age, non-wear and tear-associated arthritis in US young adults. Methods: In this cross sectional study of 1209 adults aged 20–30y, (Nutrition and Health Examination Surveys 2003–2006) exposure variables were high EFF beverages, including HFCS sweetened soft drinks, and any combination of HFCS sweetened soft drinks, fruit drinks (FD) and apple juice, referred to as tEFF. Analyses of diet soda and diet FD were included for comparison. The outcome was self-reported arthritis. Rao Scott Ҳ2 was used for prevalence differences and logistic regression for associations, adjusted for confounders. Results: Young adults consuming any combination of high EFF beverages (tEFF) ⩾5 times/week (but not diet soda) were three times as likely to have arthritis as non/low consumers (odds ratios=3.01; p⩽0.021; 95% confidence intervals=1.20–7.59), independent of all covariates, including physical activity, other dietary factors, blood glucose and smoking. Conclusion: EFF beverage intake is significantly associated with arthritis in US adults

  4. Age-related prevalence, intensity and frequency distribution of gastrointestinal helminth infection in urban slum children from Kuala Lumpur, Malaysia.

    Science.gov (United States)

    Bundy, D A; Kan, S P; Rose, R

    1988-01-01

    The gastrointestinal helminth infection status of 1574 children living in a slum area of Kuala Lumpur, Malaysia was assessed by quantitative coprology. Almost two-thirds were infected with Trichuris trichiura, 49.6% with Ascaris lumbricoides, and 5.3% with hookworm. Infection prevalence rose rapidly to a stable asymptote at 7 years of age, and the age-intensity profile was convex with maximal values in the 5-10 year age classes. This pattern was the same for males and females, but differed markedly between different ethnic groups. The frequency distributions of A. lumbricoides and T. trichiura were highly overdispersed (k values were 0.21 and 0.27, respectively), and age-dependent over the 0-8 year age classes. This suggests that the force of infection with these nematodes is lower in infants than in older children.

  5. Socioeconomic status and the prevalence of fever in children under age five: evidence from four sub-Saharan African countries

    Directory of Open Access Journals (Sweden)

    Novignon Jacob

    2012-07-01

    Full Text Available Abstract Background The burden of fevers remains enormous in sub-Saharan Africa. While several efforts at reducing the burden of fevers have been made at the macro level, the relationship between socioeconomic status and fever prevalence has been inconclusive at the household and individual levels. The purpose of this study was to examine how individual and household socioeconomic status influences the prevalence of fever among children under age five in four sub-Saharan African countries. Methods The study used data from the 2008 Demographic and Health Survey (DHS from Ghana, Nigeria, Kenya and Sierra Leone with a total of 38,990 children below age five. A multi-level random effects logistic model was fitted to examine the socioeconomic factors that influence the prevalence of fever in the two weeks preceding the survey. Data from the four countries were also combined to estimate this relationship, after country-specific analysis. Results The results show that children from wealthier households reported lower prevalence of fever in Ghana, Nigeria and Kenya. Result from the combined dataset shows that children from wealthier households were less likely to report fever. In general, vaccination against fever-related diseases and the use of improved toilet facility reduces fever prevalence. The use of bed nets by children and mothers did not show consistent relationship across the countries. Conclusion Poverty does not only influence prevalence of fever at the macro level as shown in other studies but also the individual and household levels. Policies directed towards preventing childhood fevers should take a close account of issues of poverty alleviation. There is also the need to ensure that prevention and treatment mechanisms directed towards fever related diseases (such as malaria, pneumonia, measles, diarrhoea, polio, tuberculosis etc. are accessible and effectively used.

  6. Covariant Noncommutative Field Theory

    International Nuclear Information System (INIS)

    The covariant approach to noncommutative field and gauge theories is revisited. In the process the formalism is applied to field theories invariant under diffeomorphisms. Local differentiable forms are defined in this context. The lagrangian and hamiltonian formalism is consistently introduced

  7. Prevalence of periodontitis among the adolescents aged 15-18 years in Mangalore City: An epidemiological and microbiological study

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    K Pallavi Nanaiah

    2013-01-01

    Full Text Available Background: Periodontitis is a group of inflammatory diseases affecting the supporting tissues of the tooth. Both aggressive periodontitis (AP and chronic periodontitis (CP have a multifactorial etiology, with dental plaque as the initiating factor. However, the initiation and progression of periodontitis are influenced by other factors including microbiologic, social and behavioral and systemic and genetic factors. The prevalence of periodontal diseases varies in different regions of the world according to the definition of periodontitis and the study population, and there are indications that they may be more prevalent in developing than in developed countries. Materials and Methods: A cross-sectional study was conducted among the adolescents of 15-18 years of age in Mangalore City. One thousand one hundred students aged 15-18 years were selected for the study from the schools and colleges in Mangalore City using a convenient sampling method. The prevalence of AP and CP were assessed in the study using a community periodontal index. Students who were diagnosed clinically and radiographically were subjected to microbiological examination to confirm AP. Results: A high prevalence of gingivitis and periodontitis was found in students belonging to the lower socioeconomic status group compared with the higher socioeconomic groups, which were associated with poor oral hygiene habits. The prevalence of AP was found to be 0.36% and that of CP was found to be 1.5%. Conclusion: Oral diseases have a significant impact on the social and psychological aspects of an individual′s life. Exposure to risk factors, such as age, low socio-economic status, poor education, low dental care utilization, poor oral hygiene levels, smoking, psychosocial stress and genetic factors are significantly associated with an increased risk of periodontitis among adolescents. Although genetic factors play a major role in periodontitis, the treatment outcome will still be

  8. Prevalence of common gastrointestinal nematode parasites in scavenging pigs of different ages and sexes in Eastern Centre province, Burkina Faso

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    H.H. Tamboura

    2006-09-01

    Full Text Available The range and infestation intensities of gastrointestinal parasitic nematode species depend on the type of swine production system. The present study focused mainly on nematodes of veterinary importance in scavenging pigs in Burkina Faso, and aimed at determining the prevalence of gastro-intestinal nematode parasites by means of faecal egg per gram (EPG counts. Between November 2001 and October 2002, faecal samples from 383 pigs of different sexes and ages (< 5 months, 5-12 months and > 12 months were collected from the rectum and examined for gastrointestinal nematodes parasites using the Mc Master method. Of the 383 pigs examined, 91 % were infected by one or more para sites. Ascaris suum (40 %; 100-1 400 EPG was the most prevalent parasite followed by Strongyloides ransomi (21 %; 100-4 200 EPG, Oesophagostomum spp. (18 %; 100-1 000 EPG, Hyostrongylus rubidus (11 %; 100-1 800 EPG, Globocephalus spp. 10 %; 100-400 EPG and Trichuris suis (1 %; 100-200 EPG. The prevalence was significantly higher in female pigs (n = 239 than in males. In addition, females excreted significantly (P < 0.05 more eggs in their faeces than males, except in the case of Globocephalus spp. The age of the animal had no effect on the prevalence of A. suum whereas there were significant differences in age categories concerning S. ransomi, H. rubidus, Oesophagostumum spp. and Globocephalus spp. Unexpectedly, the high prevalence of these common parasites was not accompanied by elevated EPG values, which suggests the existence of moderate infestations. The present work indicates that the common nematode infestations in pigs do not necessarily need a systematic herd anthelmintic treatment, as only a small number of worms is required to induce immunity. A further study is needed to formulate appropriate and cost-effective strategies for the control of gastro-intestinal nematode parasites in pigs in Burkina Faso.

  9. Prevalence of lead exposure among age and sex cohorts of Canada geese

    Science.gov (United States)

    DeStefano, S.; Brand, C.J.; Rusch, D.H.

    1992-01-01

    We examined the prevalence of lead exposure from ingestion of waste lead shot among age and sex cohorts of Canada geese (Branta canadensis) on the breeding, migration, and wintering grounds of the Eastern Prairie Population. Blood samples from 6963 geese were assayed for lead concentration by atomic absorption spectrophotometry. On the breeding grounds, no goslings and 1 year old) had lead concentrations greater-than-or-equal-to 0.18 ppm. Median background lead levels remained higher in adults than in immatures throughout fall and winter. We also found that more immature males than immature females had elevated lead concentrations. Higher rates of intake of food and grit (including shot) probably partially account for the higher prevalence of elevated lead concentrations in immature Canada geese.//Nous avons ??tudi?? l'importance des expositions au plomb par ingestion de plombs de chasse chez les diff??rentes cohortes (??ge et sexe) de Bernaches du Canada (Branta canadensis) dans les zones de reproduction et de migration et dans les territoires d'hiver chez la population de la Prairie de l'Est. Des ??chantillons de sang ont ??t?? pr??lev??s chez 6963 bernaches et analys??s au sphectrophotom??tre ? absorption atomique pour en d??terminer le contenu en plomb. Dans les zones de reproduction, les traces d'exposition r??cente ? des plombs (i.e. concentrations de plomb dans le sang au-dessus de la valeur seuil de 0,18 ppm) ??taient apparentes chez moins de 1% des adultes et aucun oison n'en portait. Cependant, les concentrations sanguines m??dianes de base (??chantillons de sang contenant moins de 0,18 ppm de plomb) ??taient plus ??lev??es chez les adultes que chez les oisons, ce qui signifie probablement que les adultes avaient ??t?? expos??s au plomb au cours de saisons pr??c??dentes. Les plombs perdus ??taient abondants dans les territoires de migration et les territoires d'hiver et la proportion d'??chantillons de sang contenant des concentrations a?Y 0,18 ppm ??tait

  10. State and Regional Prevalence of Diagnosed Multiple Chronic Conditions Among Adults Aged ≥18 Years - United States, 2014.

    Science.gov (United States)

    Ward, Brian W; Black, Lindsey I

    2016-01-01

    The prevalence and care management of multiple (two or more) chronic conditions (MCC) are important public health concerns (1). Approximately 25% of U.S. adults have diagnoses of MCC (2). Care management of MCC presents a challenge to both patients and providers because of the substantial costs associated with treating more than one condition and the traditional care strategies that focus on single conditions as opposed to enhanced care coordination (3,4). Maintaining surveillance, targeting service delivery, and projecting resources are all important to meet this challenge, and these actions can be informed by identifying state and other regional variations in MCC prevalence (5,6). Data from the 2014 National Health Interview Survey (NHIS) were used to estimate prevalence of MCC (defined as two or more of 10 diagnosed chronic conditions) for each U.S. state and region by age and sex. Significant state and regional variation in MCC prevalence was found, with state-level estimates ranging from 19.0% in Colorado to 38.2% in Kentucky. MCC prevalence also varied by region, ranging from 21.4% in the Pacific region to 34.5% in the East South Central region. The prevalence of MCC was higher among women than among men within certain U.S. regions, and was higher in older persons in all regions. Such findings further the research and surveillance objectives stated in the U.S. Department of Health and Human Services (HHS) publication, Multiple Chronic Conditions: A Strategic Framework (1). Furthermore, geographic disparities in MCC prevalence can inform state-level surveillance programs and groups targeting service delivery or allocating resources for MCC prevention activities. PMID:27467707

  11. Prevalence of stroke and metabolic disorders in the middle-aged and elderly Chinese with type 2 diabetes

    Institute of Scientific and Technical Information of China (English)

    Zhang Xuebing; Mu Yiming; Yan Wenhua; Ba Jianming; Li Hongmei

    2014-01-01

    Background Stroke is now the most prevalent and debilitating disease affecting diabetic population in China.The study aimed to investigate the prevalence of stroke and metabolic disorders in the middle-aged and elderly Chinese with type 2 diabetes.Methods A total of 4 629 subjects with type 2 diabetes (males:1 917; females:2 712) aged > 40 years from Shijingshan district,Beijing,China from November 2011 to August 2012 were included in the study.Data on demographic information,lifestyle,history of diabetes mellitus,stroke,coronary heart disease,hypertension,and dyslipidemia were collected.The oral glucose tolerance test or a standard meal test was performed.Non-fatal stroke was reported by the subjects.The 2-tailed test was used,and P <0.05 was regarded as statistically significant.Results Prevalence of stroke in the subjects with type 2 diabetes was 5.5%.The prevalence of smoking,overweight or obesity,hypertension,and dyslipidemia was 41.0%,65.8%,67.4%,and 52.0% in males,and 2.2%,65.5%,69.5%,and 57.6% in females.Multivariate Logistic regression analysis showed that increased age,hypertension,diabetic duration,and overweight or obesity were positively correlated with stroke in the population with type 2 diabetes,whereas highdensity lipoprotein cholesterol level was negatively correlated with stroke.After adjustment for age and gender,the odds ratio values of stroke in subjects having 1,2 or >3 of 4 risk factors,including smoking,overweight or obesity,hypertension and dyslipidemia,were 2.302 (95% CI:0.789-6.712),4.089 (95% CI:1.470-11.373),6.023 (95% CI:2.176-16.666),compared with subjects without any of the above 4 risk factors.Conclusions The prevalence of stroke was higher in middle-aged and elderly Chinese with type 2 diabetes than that in the general population.With the aggregation of risk factors,the prevalence of stroke increased.

  12. Surveys of serum reproductive hormone levels and the prevalence rates of late onset of hypogonadism in Chinese aging males

    Institute of Scientific and Technical Information of China (English)

    Zhou Shan-jie; Li Xian-kun; Lu Wen-hong; Liang Xiao-wei; Yuan Dong; Li Hong; Gu Yi-qun; Zhang Bao-long; Ji Yu-dang; Wang Can-gang

    2011-01-01

    Objective:To investigate the change patterns of reproductive hormones in serum of aging males and the difference among male age brackets and the prevalence rates of late onset of hypogonadism (LOH) in males in Chinese middle and aging males.Methods:Subjects included 1,498 men aged 40 to 69 from a county,and the serum reproductive hormones of 434 subjects were measured and calculated.In addition,the prevalence rates of LOH were analyzed by cut-off point of total testosterone (TT) and free testosterone (cFT),and screening scales (a questionnaire of androgen deficiency in the aging males (ADAM) and a scale of aging males' symptoms (AMS)).TT,cFT,bio-available testosterone (Bio-T),luteinizing hormone (LH),sex hormone binding globulin (SHBG),testosterone secretion index (TSI),free testosterone index (FTI),the positive rates of LOH screening,androgen deficiency rates and the clinical prevalence rates of LOH were measured or calculated.Results:The serum TT levels did not change significantly with male aging while serum LH and SHBG levels gradually increased,but cFT,Bio-T,TSI and FTI levels gradually decreased with male aging.There was very significant difference in other six parameters of reproductive hormones (P<0.01),except for serum TT among the four age brackets(P>0.05).There was no correlation between serum TT levels and aging,LH levels(P>0.05).However,there was significantly a positive correlation between serum LH,SHBG and age (P<0.01),while there were negative correlation between cFT,Bio-T,TSI,FTI and age,LH levels (P<0.01).Moreover,SHBG level was positively correlated with LH level (P<0.01).Utilizing the Questionnaire of ADAM and AMS to screen subjects aged 40 to 69 years,mean positive rates of LOH screening were 80.77% and 32.34% respectively.Mean androgen deficiency rates were 14.02% and 43.69%by using TT and cFT cut-off point.In addition,mean LOH clinical prevalence rates of subjects on positive questionnaire results were 37.85% and 15.42

  13. Stroke Prevalence, Mortality and Disability-Adjusted Life Years in Adults Aged 20-64 Years in 1990-2013

    DEFF Research Database (Denmark)

    Krishnamurthi, Rita V; Moran, Andrew E; Feigin, Valery L;

    2015-01-01

    in younger adults. OBJECTIVES: This study aims to estimate prevalence, mortality and disability-adjusted life years (DALYs) and their trends for total, ischemic stroke (IS) and hemorrhagic stroke (HS) in the world for 1990-2013 in adults aged 20-64 years. METHODOLOGY: Stroke prevalence, mortality and DALYs.......8 (95% UI 16.9-22.6) and 13.7 (95% UI 12.1-15.9)) per 100,000). No significant change was detected in IS death rates among younger adults. The total DALYs from all strokes in those aged 20-64 years was 51,429,440 (95% UI 46,561,382-57,320,085). Globally, there was a 24.4% (95% UI 16.6-33.8) increase...... services for stroke is required to substantially narrow these disparities. © 2015 S. Karger AG, Basel....

  14. Defining sarcopenia: the impact of different diagnostic criteria on the prevalence of sarcopenia in a large middle aged cohort

    OpenAIRE

    Bijlsma, A. Y.; Meskers, C. G. M.; Ling, C. H. Y.; Narici, M.; Kurrle, S E; Cameron, I.D.; Westendorp, R G J; Maier, A. B.

    2012-01-01

    Sarcopenia, low muscle mass, is an increasing problem in our ageing society. The prevalence of sarcopenia varies extremely between elderly cohorts ranging from 7% to over 50%. Without consensus on the definition of sarcopenia, a variety of diagnostic criteria are being used. We assessed the degree of agreement between seven different diagnostic criteria for sarcopenia based on muscle mass and handgrip strength, described in literature. In this cross-sectional study, we included men (n = 325) ...

  15. Sarcopenic Obesity: Prevalence and Association With Metabolic Syndrome in the Korean Longitudinal Study on Health and Aging (KLoSHA)

    OpenAIRE

    Lim, Soo; Kim, Jung Hee; Yoon, Ji Won; Kang, Seon Mee; Choi, Sung Hee; Park, Young Joo; Kim, Ki Woong; Lim, Jae Young; Park, Kyong Soo; Jang, Hak Chul

    2010-01-01

    OBJECTIVE We investigated the prevalence of sarcopenic obesity (SO) and its relationship with metabolic syndrome in a community-based elderly cohort in Korea. RESEARCH DESIGN AND METHODS In this study, 287 men and 278 women aged 65 or older were recruited. Sarcopenia was defined as the appendicular skeletal muscle mass (ASM) divided by height squared (Ht2) (kg/m2) or by weight (Wt) (%) of

  16. The Prevalence of Using Iodine-Containing Supplements Is Low among Reproductive-Age Women, NHANES 1999–200612

    OpenAIRE

    Gahche, Jaime J; Bailey, Regan L; Mirel, Lisa B.; Dwyer, Johanna T

    2013-01-01

    During pregnancy, the iodine requirement rises to meet demands for neurological development and fetal growth. If these requirements are not met, irreversible pathological cognitive and behavioral changes to the fetus may ensue. This study estimated the prevalence of iodine-containing dietary supplement (DS) use and intakes of iodine from DSs among pregnant women and nonpregnant women of reproductive age (15–39 y) who were interviewed and examined in NHANES 1999–2006 (n = 6404). Although 77.5%...

  17. Evaluation of Goiter Prevalence and Iodine to Creatinine Ratio among School-aged Girls in Urmia County

    OpenAIRE

    J Nourooz-Zadeh; MR Aghasi; H Estabraghnia; A Biravand; Rostami, R.

    2013-01-01

    Introduction: Clinical evaluation of iodine deficiency disorders (IDDs) is often accomplished by assessment of urinary iodine excretion (UIE) in random samples; however, the utilization of 24 hour urine samples is a more reliable biomarker of nutritional iodine status. This study was designed to evaluate total goiter prevalence (TGP) and iodine/creatinine ratio among school-aged children in Urmia County. Methods: Schoolchildren (n=500) were recruited by cluster sampling from different educati...

  18. A Bayesian approach to estimate the prevalence of low height-for-age from the prevalence of low weight-for-age Uma abordagem Bayesiana para obter estimativas de prevalência de déficit de crescimento com base na prevalência de baixo peso para idade

    Directory of Open Access Journals (Sweden)

    Michael E. Reichenheim

    2000-06-01

    Full Text Available Victora et al. (1998 proposed the use of low weight-for-age prevalence to estimate the prevalence of height-for-age deficit in Brazilian children. This procedure was justified by the need to simplify methods used in the context of community health programs. From the same perspective, the present article broadens this proposal by using a Bayesian approach (based on Markov Chain Monte Carlo (MCMC methods to deal with the imprecision resulting from Victora et al.'s model. In order to avoid invalid estimated prevalence values which can occur with the original linear model, truncation or a logit transformation of the prevalences are suggested. The Bayesian approach is illustrated using a community study as an example. Imprecision arising from methodological complexities in the community study design, such as multi-stage sampling and clustering, is easily handled within the Bayesian framework by introducing a hierarchical or multilevel model structure. Since growth deficit was also evaluated in the community study, the article may also serve to validate the procedure proposed by Victora et al.Victora et al. (1998 propuseram o uso de estimativas de prevalência de baixo peso para idade para a estimação de déficit de altura para idade em crianças brasileiras, em virtude da necessidade de simplificar métodos usados em programas de saúde comunitária. Este artigo tenta aprofundar o referido estudo ao propor uma abordagem Bayesiana com base no método de Simulação Estocástica via Cadeia de Markov (SEvCM, para lidar com questões de imprecisão ligadas à modelagem de estimação do déficit de estatura. Para evitar valores inválidos de prevalência estimados pelo modelo linear sugerido originalmente, propõem-se duas alternativas: um truncamento dos valores que extrapolem os limites plausíveis de prevalência ou uma transformação logito das prevalências. A abordagem Bayesiana é ilustrada com um exemplo de um estudo comunitário. Imprecis

  19. Epstein-Barr virus (EBV infection in Chinese children: a retrospective study of age-specific prevalence.

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    Geng Xiong

    Full Text Available BACKGROUND: Epstein-Barr Virus (EBV is a globally prevalent herpesvirus associated with infectious mononucleosis and many malignancies. The survey on EBV prevalence appears to be important to study EBV-related diseases and determine when to administer prophylactic vaccine. The purpose of this retrospective study was to collect baseline information about the prevalence of EBV infection in Chinese children. METHODOLOGY/PRINCIPAL FINDING: We collected 1778 serum samples from healthy children aged 0 to 10, who were enrolled in conventional health and nutrition examinations without any EBV-related symptom in 2012 and 2013 in North China (n = 973 and South China (n = 805. We detected four EBV-specific antibodies, i.e., anti-VCA-IgG and IgM, anti-EBNA-IgG and anti-EA-IgG, by ELISA, representing all of the phases of EBV infection. The overall EBV seroprevalence in samples from North and South China were 80.78% and 79.38% respectively. The EBV seropositivity rates dropped slightly at age 2, and then increased gradually with age. The seroprevalence became stabilized at over 90% after age 8. In this study, the seroprevalence trends between North and South China showed no difference (P>0.05, and the trends of average antibody concentrations were similar as well (P>0.05. CONCLUSIONS/SIGNIFICANCE: EBV seroprevalence became more than 50% before age 3 in Chinese children, and exceed 90% after age 8. This study can be helpful to study the relationship between EBV and EBV-associated diseases, and supportive to EBV vaccine development and implementation.

  20. Prevalence and impact of primary headache disorders among students and working population in 18-25 years age group

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    Gowri Aishwarya S, Eswari N, Chandrasekar M, Chandra Prabha J

    2014-04-01

    Full Text Available Background: Headache or cephalalgia is defined as pain in the head. Headache is an extremely common symptom that may have a profound impact on peoples’ functioning and quality of life. According to International Classification of Headache Disorders (ICHD, they are Primary and Secondary headaches. Primary Headaches are triggered by stress, alcohol, changes in sleep pattern, anxiety, poor posture, all of which are part and parcel our day-to-day life. The study was performed to investigate the prevalence of primary headache disorders and its severity of impact among students and working population in the age group 18-25. Methods: The study was conducted on 718 subjects of which 483 subjects were medical and engineering students from the age group 18-21 and 235 subjects were working people from the age group 22-25. Written consent was taken from each of them. Headache Impact Test-6 (version 1.1 and the HARDSHIP Questionnaire by Timothy Steiner et al. were the questionnaires used to diagnose the severity of impact and the type of headache respectively. The study was ethically approved by Ethical Clearance Board of MAHER University. People suffering from psychiatric illness were excluded from the study. Result: There was increased prevalence of migraine in the age group 18-21 and tension type headache in the age group 22-25.Over 50%of subjects from both the age groups had headaches that have substantial to severe impact on their lives. There was no significant gender variation in headache prevalence.

  1. Differences in oral sexual behaviors by gender, age, and race explain observed differences in prevalence of oral human papillomavirus infection.

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    Gypsyamber D'Souza

    Full Text Available PURPOSE: This study explores whether gender, age and race differences in oral sexual behavior account for the demographic distribution of oral human papillomavirus infection (HPV and HPV-positive oropharyngeal cancer (HPV-OSCC. METHODS: This analysis included 2,116 men and 2,140 women from NHANES (2009-10 who answered a behavioral questionnaire and provided an oral-rinse sample for HPV detection. Weighted prevalence estimates and prevalence ratios (PR were calculated for sexual behaviors and oral HPV infection by gender, age-cohort (20-29, 30-44, 45-59, 60-69, and race, and contrasted with incidence rate ratios (IRR of OSCC from SEER 2009. Multivariate logistic regression was used to evaluate predictors of oral sexual behavior and oral HPV16 infection. RESULTS: Differences in oral sexual behavior were observed by gender, age-cohort and race. Most men (85.4% and women (83.2% had ever performed oral sex, but men had more lifetime oral and vaginal sexual partners and higher oral HPV16 prevalence than women (each p<0.001. 60-69 year olds (yo were less likely than 45-59 or 30-44 (yo to have performed oral sex (72.7%, 84.8%, and 90.3%, p<0.001, although oral HPV16 prevalence was similar. Prevalence ratios (PR of ever oral sex in men vs. women (PR = 1.03, and 45-59 vs. 30-44 year-old men (PR = 0.96 were modest relative to ratios for oral HPV16 infection (PRs = 1.3-6.8 and OSCC (IRR = 4.7-8.1. In multivariate analysis, gender, age-cohort, and race were significant predictors of oral sexual behavior. Oral sexual behavior was the primary predictor of oral HPV16 infection; once this behavior was adjusted for, age-cohort and race were no longer associated with oral HPV16. CONCLUSION: There are differences in oral sexual behaviors when considering gender, age-cohort and race which explain observed epidemiologic differences in oral HPV16 infection across these groups.

  2. Geostatistical model-based estimates of Schistosomiasis prevalence among individuals aged ≤ 20 years in West Africa.

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    Nadine Schur

    2011-06-01

    Full Text Available BACKGROUND: Schistosomiasis is a water-based disease that is believed to affect over 200 million people with an estimated 97% of the infections concentrated in Africa. However, these statistics are largely based on population re-adjusted data originally published by Utroska and colleagues more than 20 years ago. Hence, these estimates are outdated due to large-scale preventive chemotherapy programs, improved sanitation, water resources development and management, among other reasons. For planning, coordination, and evaluation of control activities, it is essential to possess reliable schistosomiasis prevalence maps. METHODOLOGY: We analyzed survey data compiled on a newly established open-access global neglected tropical diseases database (i to create smooth empirical prevalence maps for Schistosoma mansoni and S. haematobium for individuals aged ≤ 20 years in West Africa, including Cameroon, and (ii to derive country-specific prevalence estimates. We used Bayesian geostatistical models based on environmental predictors to take into account potential clustering due to common spatially structured exposures. Prediction at unobserved locations was facilitated by joint kriging. PRINCIPAL FINDINGS: Our models revealed that 50.8 million individuals aged ≤ 20 years in West Africa are infected with either S. mansoni, or S. haematobium, or both species concurrently. The country prevalence estimates ranged between 0.5% (The Gambia and 37.1% (Liberia for S. mansoni, and between 17.6% (The Gambia and 51.6% (Sierra Leone for S. haematobium. We observed that the combined prevalence for both schistosome species is two-fold lower in Gambia than previously reported, while we found an almost two-fold higher estimate for Liberia (58.3% than reported before (30.0%. Our predictions are likely to overestimate overall country prevalence, since modeling was based on children and adolescents up to the age of 20 years who are at highest risk of infection. CONCLUSION

  3. Ethnicity, location, age, and fluoridation factors in baby bottle tooth decay and caries prevalence of Head Start children.

    Science.gov (United States)

    Barnes, G P; Parker, W A; Lyon, T C; Drum, M A; Coleman, G C

    1992-01-01

    Baby bottle tooth decay (BBTD) is a term applied to a specific form of rampant decay associated with inappropriate bottle or breast feeding of infants and young children. Although the prevalence of BBTD has been studied in individual ethnic groups, comparison studies are rare. Head Start children have frequently served as study subjects for assessing the prevalence of BBTD. The purpose of this study was to compare BBTD and caries prevalence among Head Start children who are members of four ethnic groups in five southwestern States. Age, residence, and fluoridation status were also compared for the total sample and ethnic categories. The sampling process was a stratified random site selection; it was used to obtain data on 1,230 children. This number constituted 3 percent of the children enrolled in Head Start in Public Health Service Region VI (Arkansas, Louisiana, New Mexico, Oklahoma, and Texas) where the study was conducted. The criterion for determining the presence of BBTD was based on the number of carious deciduous maxillary incisors observed. The severity of the condition was reported as two of four and three of four of the target teeth affected. Thus, two levels of severity are reported. BBTD was prevalent in approximately 24 percent and 15 percent of the total sample, depending on the severity criterion used. Native American children had a significantly higher (P less than 0.05) prevalence than Hispanic, white, and black subjects. Rural children had significantly higher (P less than 0.05) prevalence of BBTD than nonrural children for all ethnic groups except whites. The prevalence of decayed and filled (df) surfaces of primary dentition was significantly greater for all rural than for non rural groups (P< 0.05).Children attending centers showed no significant differences based on fluoride status for the total sample or other variables. BBTD and caries prevalence increased with age. Studies are needed to identify predisposing factors among the ethnic

  4. Prevalence and risk factors of anaemia among children aged between 6 months and 14 years in Kenya.

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    Oscar Ngesa

    Full Text Available Anaemia is one of the significant public health problems among children in the world. Understanding risk factors of anaemia provides more insight to the nature and types of policies that can be put up to fight anaemia. We estimated the prevalence and risk factors of anaemia in a population-based, cross-sectional survey.Blood samples from 11,711 children aged between 6 months and 14 years were collected using a single-use, spring-loaded, sterile lancet to make a finger prick. Anaemia was measured based on haemoglobin concentration level. The generalized linear model framework was used to analyse the data, in which the response variable was either a child was anemic or not anemic.The overall prevalence of anaemia among the children in Kenya was estimated to be 28.8%. Across each band of age within which the definition of anaemia remained constant (0–4, 5–11, and 12–14 years old, the prevalence of anaemia declined with each year of age. [corrected]. The risk of anaemia was significantly higher in male than female children. Mothers with secondary and above education had a protective effect on the risk of anaemia on their children. Malaria diagnosis status of a child was positively associated with risk anaemia.Controlling co-morbidity of malaria and improving maternal knowledge are potential options for reducing the burden of anaemia.

  5. The Prevalence of Anxiety and its related Factors among School-age Children in South West of Iran

    OpenAIRE

    Zeinab Banaeipour; Shahnaz Rostami; Kourosh Zarea; Bahman Cheraghian

    2016-01-01

    Background Anxiety is one of the most common childhood disorders, so it is necessary to explore extend and its related factors in the students. This study was conducted to determine the prevalence of anxiety and the related factors of anxiety among the children aged 9-12 years. Materials and Methods At a descriptive-analytic study 623 children aged 9-12 year- old who were studying in the fourth to sixth grade of elementary school in Dezful city, were selected through multistage random samplin...

  6. Age- and Gender-Specific Prevalence of Risk Factors in Patients with First-Ever Ischemic Stroke in China

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    Xiao-ying Yao

    2012-01-01

    Full Text Available Background. Evidences are accumulating that age and gender have great impact on the distribution of stroke risk factors. Such data are lacking in Chinese population. Methods. 1027 patients with first-ever ischemic stroke (IS were recruited and divided into young adult (80 years groups according to stroke onset ages. Vascular risk factors were collected and compared among groups. Results. Female patients were globally older than male patients at stroke onset and having higher prevalence of diabetes mellitus (DM, heart diseases, and atrial fibrillation (AF. However, females were less likely to drink heavily or smoke than males. Young patients had a much higher proportion of smoking and drinking than middle-aged and very old patients and the highest family history of hypertension, while very old patients had the highest prevalence of heart diseases and AF but lowest proportion of positive family history of vascular diseases. Hypertension and DM were equally frequent among three groups. Conclusion. Our study showed that vascular risk factors had a specific age and gender distribution pattern in Chinese IS patients. Secondary prevention strategy should emphasize on the control of different risk factors based on patient’s age and gender.

  7. Diabetes and pre-diabetes among persons aged 35 to 60 years in eastern Uganda: prevalence and associated factors.

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    Roy William Mayega

    Full Text Available BACKGROUND: Our aim was to estimate the prevalence of abnormal glucose regulation (AGR (i.e. diabetes and pre-diabetes and its associated factors among people aged 35-60 years so as to clarify the relevance of targeted screening in rural Africa. METHODS: A population-based survey of 1,497 people (786 women and 711 men aged 35-60 years was conducted in a predominantly rural Demographic Surveillance Site in eastern Uganda. Participants responded to a lifestyle questionnaire, following which their Body Mass Index (BMI and Blood Pressure (BP were measured. Fasting plasma glucose (FPG was measured from capillary blood using On-Call® Plus (Acon rapid glucose meters, following overnight fasting. AGR was defined as FPG ≥6.1 mmol L⁻¹ (World Health Organization (WHO criteria or ≥5.6 mmol L⁻¹ (American Diabetes Association (ADA criteria. Diabetes was defined as FPG >6.9 mmol L⁻¹, or being on diabetes treatment. RESULTS: The mean age of participants was 45 years for men and 44 for women. Prevalence of diabetes was 7.4% (95%CI 6.1-8.8, while prevalence of pre-diabetes was 8.6% (95%CI 7.3-10.2 using WHO criteria and 20.2% (95%CI 17.5-22.9 with ADA criteria. Using WHO cut-offs, the prevalence of AGR was 2 times higher among obese persons compared with normal BMI persons (Adjusted Prevalence Rate Ratio (APRR 1.9, 95%CI 1.3-2.8. Occupation as a mechanic, achieving the WHO recommended physical activity threshold, and higher dietary diversity were associated with lower likelihood of AGR (APRR 0.6, 95%CI 0.4-0.9; APRR 0.6, 95%CI 0.4-0.8; APRR 0.5, 95%CI 0.3-0.9 respectively. The direct medical cost of detecting one person with AGR was two US dollars with ADA and three point seven dollars with WHO cut-offs. CONCLUSIONS: There is a high prevalence of AGR among people aged 35-60 years in this setting. Screening for high risk persons and targeted health education to address obesity, insufficient physical activity and non-diverse diets are necessary.

  8. Multiple Comorbid Conditions among Middle-Aged and Elderly Hemophilia Patients: Prevalence Estimates and Implications for Future Care

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    Aroub A. Khleif

    2011-01-01

    Full Text Available Introduction. Advances in hemophilia care and treatment have led to increases in the life expectancy among hemophiliacs. As a result, persons with hemophilia are reaching an older age and experiencing various age-related health conditions never seen before in this population. Aim. To determine the prevalence of comorbidities among middle-aged and elderly hemophilia A and hemophilia B patients. Methods. Retrospective chart review among all hemophilia patients, who attended the Gulf States Hemophilia and Thrombophilia Center. Results. All patients had at least one comorbid condition other than hemophilia, and the majority had between 3 and 6 comorbidities. The most common conditions identified were chronic hepatitis C, hypertension, HIV, chronic arthropathy, and overweight/obesity. Conclusions. Since persons with comorbidities are more likely to have poorer health outcomes and require greater care in managing their health needs, caring for aging hemophiliacs is likely to pose various social and economic challenges for both patients and providers.

  9. Aging with HIV: a cross-sectional study of comorbidity prevalence and clinical characteristics across decades of life.

    Science.gov (United States)

    Vance, David E; Mugavero, Michael; Willig, James; Raper, James L; Saag, Michael S

    2011-01-01

    Nurses and nurse practitioners require information on the health problems faced by aging HIV-infected adults. In this descriptive, cross-sectional study, we reviewed the electronic medical records of 1,478 adult patients seen in an HIV clinic between May 2006 and August 2007 to examine patterns of comorbidities, and immunological and clinical characteristics across each decade of life. With increasing age, patients were found to have lower HIV viral loads, more prescribed medications, and a higher prevalence of comorbid conditions, including coronary artery disease, hypertension, hypercholesterolemia, hypogonadism, erectile dysfunction, diabetes, peripheral neuropathy, hepatitis C, esophageal gastric reflux disease, and renal disease. Fortunately, with increasing age, patients were also more likely to have public or private health insurance and tended to be more compliant to medical appointments. With growing interest in aging with HIV, this study highlights the vastly different comorbidity profiles across decades of life, calling into question what constitutes "older" with HIV. PMID:20471864

  10. Age, season and spatio-temporal factors affecting the prevalence of Echinococcus multilocularis and Taenia taeniaeformis in Arvicola terrestris

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    Deplazes Peter

    2011-01-01

    Full Text Available Abstract Background Taenia taeniaeformis and the related zoonotic cestode Echinococcus multilocularis both infect the water vole Arvicola terrestris. We investigated the effect of age, spatio-temporal and season-related factors on the prevalence of these parasites in their shared intermediate host. The absolute age of the voles was calculated based on their eye lens weights, and we included the mean day temperature and mean precipitation experienced by each individual as independent factors. Results Overall prevalences of E. multilocularis and T. taeniaeformis were 15.1% and 23.4%, respectively, in 856 A. terrestris trapped in the canton Zürich, Switzerland. Prevalences were lower in young (≤ 3 months: E. multilocularis 7.6%, T. taeniaeformis 17.9% than in older animals (>7 months: 32.6% and 34.8%. Only 12 of 129 E. multilocularis-infected voles harboured protoscoleces. Similar proportions of animals with several strobilocerci were found in T. taeniaeformis infected voles of E. multilocularis. In one trapping area, prevalences varied on an exceptional high level of 40.6-78.5% during the whole study period. Low temperatures significantly correlated with the infection rate whereas precipitation was of lower importance. Significant spatial variations in prevalences were also identified for Taenia taeniaeformis. Although the trapping period and the meteorological factors temperature and precipitation were included in the best models for explaining the infection risk, their effects were not significant for this parasite. Conclusions Our results demonstrate that, besides temporal and spatial factors, low temperatures contribute to the risk of infection with E. multilocularis. This suggests that the enhanced survival of E. multilocularis eggs under cold weather conditions determines the level of infection pressure on the intermediate hosts and possibly also the infection risk for human alveolar echincoccosis (AE. Therefore, interventions against the

  11. Covariance mapping techniques

    Science.gov (United States)

    Frasinski, Leszek J.

    2016-08-01

    Recent technological advances in the generation of intense femtosecond pulses have made covariance mapping an attractive analytical technique. The laser pulses available are so intense that often thousands of ionisation and Coulomb explosion events will occur within each pulse. To understand the physics of these processes the photoelectrons and photoions need to be correlated, and covariance mapping is well suited for operating at the high counting rates of these laser sources. Partial covariance is particularly useful in experiments with x-ray free electron lasers, because it is capable of suppressing pulse fluctuation effects. A variety of covariance mapping methods is described: simple, partial (single- and multi-parameter), sliced, contingent and multi-dimensional. The relationship to coincidence techniques is discussed. Covariance mapping has been used in many areas of science and technology: inner-shell excitation and Auger decay, multiphoton and multielectron ionisation, time-of-flight and angle-resolved spectrometry, infrared spectroscopy, nuclear magnetic resonance imaging, stimulated Raman scattering, directional gamma ray sensing, welding diagnostics and brain connectivity studies (connectomics). This review gives practical advice for implementing the technique and interpreting the results, including its limitations and instrumental constraints. It also summarises recent theoretical studies, highlights unsolved problems and outlines a personal view on the most promising research directions.

  12. Neurofibromatosis 1 prevalence in children aged 9-11 years, Pinar del Río Province, Cuba.

    Science.gov (United States)

    Orraca, Miladys; Morejón, Griselda; Cabrera, Niurka; Menéndez, Reinaldo; Orraca, Odalys

    2014-01-01

    INTRODUCTION Neurofibromatosis 1 is one of the most common heritable genetic disorders in humans. It is characterized by formation of neurofibromas, with marked variability in expression. Half the cases are due to autosomal dominant inheritance; the rest arise from de novo mutations. Prevalence varies by population, and prevalence in Cuba is unknown. OBJECTIVE Determine the prevalence of neurofibromatosis 1 in a population of Cuban children aged 9-11 years old in Pinar del Río Province, Cuba. METHODS A descriptive cross-sectional study was carried out in Pinar del Río Province in 2004, in which 19,392 children were assessed for neurofibromatosis 1. The study was conducted in two phases: the first, a survey of the entire population aged 9-11 years by genetic counselors in the province's schools; the second, assessment by clinical geneticists of children who met criteria for referral to the Provincial Medical Genetics Center. Neurofibromatosis 1 cases and first-degree relatives were examined to identify the origin of the mutation (de novo or inherited). Neurofibromatosis 1 prevalence was calculated, as well as history of a first-degree relative with the disease and frequency of several principal clinical signs-café au lait spots, freckles in places unexposed to sunlight, presence of neurofibromas, Lisch nodules and characteristic bone lesions. RESULTS Of the eligible population, 99.3% was screened (10,034 boys and 9358 girls). Active case finding resulted in referral of 200 children to medical geneticists and the disease was confirmed in 17, for a prevalence of one case per 1141 children aged 9-11 years old. Café au lait spots were the most frequent sign (100%), followed by freckles in areas unexposed to sunlight (82.4%) and characteristic bone lesions (41.2%). Only 4 of the 17 cases were previously being treated for the disease. CONCLUSIONS Neurofibromatosis 1 has high prevalence in the group studied in Pinar del Rio Province and most cases are not detected in

  13. Prevalence of testicular microlithiasis in males aged 0 to 18 years referred for scrotal sonography

    NARCIS (Netherlands)

    Goede, J.; Hofman, H.A.; Wagenvoort, A.M.; Pierik, F.H.; Hack, W.W.M.

    2012-01-01

    Background: Testicular microlithiasis (TM) is a relatively uncommon and usually asymptomatic condition that is characterized by multiple 1-3 mm nonshadowing echogenic foci within the parenchyma of the testis. Objectives: The prevalence of testicular microlithiasis was assessed retrospectively in mal

  14. Prevalence of asthma symptoms among adults aged 20-44 years in Canada

    DEFF Research Database (Denmark)

    Manfreda, J; Becklake, M R; Sears, M R;

    2001-01-01

    Reported prevalence rates of asthma vary within and between countries around the world. These differences suggest environmental factors in addition to genetic factors in the cause of the disease and may provide clues for preventive strategies. We examined the variability of asthma-related symptom...

  15. Specific and unspecific gynecological alarm symptoms -prevalence estimates in different age groups

    DEFF Research Database (Denmark)

    Balasubramaniam, Kirubakaran; Ravn, Pernille; Larsen, Pia V;

    2015-01-01

    or above from the general population. METHODS: An internet-based questionnaire study regarding the prevalence estimates of symptom experiences. A total of 18 symptoms of cervical, endometrial and ovarian cancer were selected through an extensive literature search, which included national and...

  16. Prevalence and risk indicators of depression in elderly nursing home patients : the AGED study

    NARCIS (Netherlands)

    Jongenelis, K; Eisses, AMH; Beekman, ATF; Kluiter, H; Ribbe, MW

    2004-01-01

    Background: Depression is a common and disabling psychiatric disorder in later life. Particular frail nursing home patients seem to be at increased risk. Nursing home-based studies on risk indicators of depression are scarce. Methods: Prevalence and risk indicators of depression were assessed in 333

  17. A Study of Prevalence of Risk Factors for Coronary Artery Diseases in Asymptomatic Middle Aged and Elderly Subjects

    Directory of Open Access Journals (Sweden)

    Arvind Kumar, Sandeep Garg, Hem Lata Gupta

    2005-04-01

    Full Text Available This study was conducted to determine the prevalence of risk factors for coronary artery disease(CAD in apparently healthy middle aged and elderly population and to find the different betweenurban and rural group.Atotal of 160 individuals (80 urban and 80 rural were included in the study.All the subjects underwent detailed history and physical examination with special emphasis oncardiovascular system. The biochemical investigations were done in all the subjects which includedblood sugar, serum LDL and serum triglyceride levels. The prevalence of 2 or more than 2 riskfactors were observed in 95% subjects. The prevalence of smoking was 63%, which was moreprevalent in the rural population. The sedentary lifestyle was seen in 80% subjects more in femalesand urban group. The prevalence of asymptomatic hypertensives and isolated systolic hypertensionwere seen in 34% and 10% individuals respectively. Other risk factors were-diabetes mellitus (4%,Increase LDL (38%, hypertriglyceridemia (23% and central obesity (27.50%. The two mostcommon risk factors for CADwere sedentary lifestyle and smoking. These risk factors are modifiableand their reduction during adulthood can lead to marked reduction in the burden of CAD in middleaged and elderly Indian population.

  18. Covariant canonical quantization

    Energy Technology Data Exchange (ETDEWEB)

    Hippel, G.M. von [University of Regina, Department of Physics, Regina, Saskatchewan (Canada); Wohlfarth, M.N.R. [Universitaet Hamburg, Institut fuer Theoretische Physik, Hamburg (Germany)

    2006-09-15

    We present a manifestly covariant quantization procedure based on the de Donder-Weyl Hamiltonian formulation of classical field theory. This procedure agrees with conventional canonical quantization only if the parameter space is d=1 dimensional time. In d>1 quantization requires a fundamental length scale, and any bosonic field generates a spinorial wave function, leading to the purely quantum-theoretical emergence of spinors as a byproduct. We provide a probabilistic interpretation of the wave functions for the fields, and we apply the formalism to a number of simple examples. These show that covariant canonical quantization produces both the Klein-Gordon and the Dirac equation, while also predicting the existence of discrete towers of identically charged fermions with different masses. Covariant canonical quantization can thus be understood as a ''first'' or pre-quantization within the framework of conventional QFT. (orig.)

  19. Covariant canonical quantization

    CERN Document Server

    Von Hippel, G M; Hippel, Georg M. von; Wohlfarth, Mattias N.R.

    2006-01-01

    We present a manifestly covariant quantization procedure based on the de Donder-Weyl Hamiltonian formulation of classical field theory. Covariant canonical quantization agrees with conventional canonical quantization only if the parameter space is d=1 dimensional time. In d>1 quantization requires a fundamental length scale, and any bosonic field generates a spinorial wave function, leading to the purely quantum-theoretical emergence of spinors as a byproduct. We provide a probabilistic interpretation of the wave functions for the fields, and apply the formalism to a number of simple examples. These show that covariant canonical quantization produces both the Klein-Gordon and the Dirac equation, while also predicting the existence of discrete towers of identically charged fermions with different masses.

  20. Prevalence of a few variant dental features in children aged 11–16 years in Davangere, a city in Karnataka

    Science.gov (United States)

    Poornima, P.; Kirthiga, M.; Sasalwad, Shilpa; Nagaveni, N. B.

    2016-01-01

    Context: Variations in morphology of shape of teeth have always been of interest to dentists from ancient times. But to our surprise, till date, no studies related to the prevalence of dental features have been conducted in any part of the world. Aims: To evaluate the prevalence of a few variant dental features in a group of children aged from 11 to 16 years in the city of Davangere that belongs to the state of Karnataka, India. Materials and Methods: A cross-sectional survey was conducted where children aged 11–16 years were selected (both girls and boys) and type III clinical examination was done. They were checked for the following features – Carabelli's cusp, 3-cusped maxillary 2nd molar, 5-cusped maxillary 1st molar, 4-cusped mandibular 1st molar, 5-cusped mandibular 2nd molar, cusp 6 present in mandibular 1st molar, and 7-cusped mandibular 1st molar. Statistical Analysis Used: The Chi-square test was used to analyze the categorical data. P value of 0.05 or less was considered for statistical significance. Results: Around 99.3% of the school children examined had at least one of the dental variations that were examined in relation to the shape of teeth. Conclusions: This study definitely provides us with baseline data, but further epidemiological studies are required to determine the prevalence of the above mentioned dental anomalies. PMID:27051217

  1. Informed Conditioning on Clinical Covariates Increases Power in Case-Control Association Studies

    Science.gov (United States)

    Zaitlen, Noah; Lindström, Sara; Pasaniuc, Bogdan; Cornelis, Marilyn; Genovese, Giulio; Pollack, Samuela; Barton, Anne; Bickeböller, Heike; Bowden, Donald W.; Eyre, Steve; Freedman, Barry I.; Friedman, David J.; Field, John K.; Groop, Leif; Haugen, Aage; Heinrich, Joachim; Henderson, Brian E.; Hicks, Pamela J.; Hocking, Lynne J.; Kolonel, Laurence N.; Landi, Maria Teresa; Langefeld, Carl D.; Le Marchand, Loic; Meister, Michael; Morgan, Ann W.; Raji, Olaide Y.; Risch, Angela; Rosenberger, Albert; Scherf, David; Steer, Sophia; Walshaw, Martin; Waters, Kevin M.; Wilson, Anthony G.; Wordsworth, Paul; Zienolddiny, Shanbeh; Tchetgen, Eric Tchetgen; Haiman, Christopher; Hunter, David J.; Plenge, Robert M.; Worthington, Jane; Christiani, David C.; Schaumberg, Debra A.; Chasman, Daniel I.; Altshuler, David; Voight, Benjamin; Kraft, Peter; Patterson, Nick; Price, Alkes L.

    2012-01-01

    Genetic case-control association studies often include data on clinical covariates, such as body mass index (BMI), smoking status, or age, that may modify the underlying genetic risk of case or control samples. For example, in type 2 diabetes, odds ratios for established variants estimated from low–BMI cases are larger than those estimated from high–BMI cases. An unanswered question is how to use this information to maximize statistical power in case-control studies that ascertain individuals on the basis of phenotype (case-control ascertainment) or phenotype and clinical covariates (case-control-covariate ascertainment). While current approaches improve power in studies with random ascertainment, they often lose power under case-control ascertainment and fail to capture available power increases under case-control-covariate ascertainment. We show that an informed conditioning approach, based on the liability threshold model with parameters informed by external epidemiological information, fully accounts for disease prevalence and non-random ascertainment of phenotype as well as covariates and provides a substantial increase in power while maintaining a properly controlled false-positive rate. Our method outperforms standard case-control association tests with or without covariates, tests of gene x covariate interaction, and previously proposed tests for dealing with covariates in ascertained data, with especially large improvements in the case of case-control-covariate ascertainment. We investigate empirical case-control studies of type 2 diabetes, prostate cancer, lung cancer, breast cancer, rheumatoid arthritis, age-related macular degeneration, and end-stage kidney disease over a total of 89,726 samples. In these datasets, informed conditioning outperforms logistic regression for 115 of the 157 known associated variants investigated (P-value = 1×10−9). The improvement varied across diseases with a 16% median increase in χ2 test statistics and a

  2. Informed conditioning on clinical covariates increases power in case-control association studies.

    Directory of Open Access Journals (Sweden)

    Noah Zaitlen

    Full Text Available Genetic case-control association studies often include data on clinical covariates, such as body mass index (BMI, smoking status, or age, that may modify the underlying genetic risk of case or control samples. For example, in type 2 diabetes, odds ratios for established variants estimated from low-BMI cases are larger than those estimated from high-BMI cases. An unanswered question is how to use this information to maximize statistical power in case-control studies that ascertain individuals on the basis of phenotype (case-control ascertainment or phenotype and clinical covariates (case-control-covariate ascertainment. While current approaches improve power in studies with random ascertainment, they often lose power under case-control ascertainment and fail to capture available power increases under case-control-covariate ascertainment. We show that an informed conditioning approach, based on the liability threshold model with parameters informed by external epidemiological information, fully accounts for disease prevalence and non-random ascertainment of phenotype as well as covariates and provides a substantial increase in power while maintaining a properly controlled false-positive rate. Our method outperforms standard case-control association tests with or without covariates, tests of gene x covariate interaction, and previously proposed tests for dealing with covariates in ascertained data, with especially large improvements in the case of case-control-covariate ascertainment. We investigate empirical case-control studies of type 2 diabetes, prostate cancer, lung cancer, breast cancer, rheumatoid arthritis, age-related macular degeneration, and end-stage kidney disease over a total of 89,726 samples. In these datasets, informed conditioning outperforms logistic regression for 115 of the 157 known associated variants investigated (P-value = 1 × 10(-9. The improvement varied across diseases with a 16% median increase in χ(2 test statistics

  3. Covariance Applications with Kiwi

    Directory of Open Access Journals (Sweden)

    Elliott J.B.

    2012-05-01

    Full Text Available The Computational Nuclear Physics group at Lawrence Livermore National Laboratory (LLNL is developing a new tool, named ‘Kiwi’, that is intended as an interface between the covariance data increasingly available in major nuclear reaction libraries (including ENDF and ENDL and large-scale Uncertainty Quantification (UQ studies. Kiwi is designed to integrate smoothly into large UQ studies, using the covariance matrix to generate multiple variations of nuclear data. The code has been tested using critical assemblies as a test case, and is being integrated into LLNL's quality assurance and benchmarking for nuclear data.

  4. The covariant chiral ring

    Science.gov (United States)

    Bourget, Antoine; Troost, Jan

    2016-03-01

    We construct a covariant generating function for the spectrum of chiral primaries of symmetric orbifold conformal field theories with N = (4 , 4) supersymmetry in two dimensions. For seed target spaces K3 and T 4, the generating functions capture the SO(21) and SO(5) representation theoretic content of the chiral ring respectively. Via string dualities, we relate the transformation properties of the chiral ring under these isometries of the moduli space to the Lorentz covariance of perturbative string partition functions in flat space.

  5. The Covariant Chiral Ring

    CERN Document Server

    Bourget, Antoine

    2015-01-01

    We construct a covariant generating function for the spectrum of chiral primaries of symmetric orbifold conformal field theories with N=(4,4) supersymmetry in two dimensions. For seed target spaces K3 and T4, the generating functions capture the SO(21) and SO(5) representation theoretic content of the chiral ring respectively. Via string dualities, we relate the transformation properties of the chiral ring under these isometries of the moduli space to the Lorentz covariance of perturbative string partition functions in flat space.

  6. Prevalence and causes of visual impairment according to World Health Organization and United States criteria in an aged, urban Scandinavian population

    DEFF Research Database (Denmark)

    Buch, Helena; Vinding, T; Nielsen, N V

    2001-01-01

    PURPOSE: To evaluate the prevalence and causes of visual impairment in an epidemiologic study of aged, urban individuals in Denmark. DESIGN: Cross-sectional study. PARTICIPANTS: The study population consisted of 1000 randomly selected residents aged 60 to 80 years in Copenhagen, Denmark. Of 976...... eligible persons, 946 (96.9%) could be examined. Information about best-corrected visual acuity (VA) was obtained from 944 cooperative persons (96.7%). METHODS: Data from the Copenhagen City Eye Study were used to assess the cause-specific prevalence of visual impairment as defined by the World Health...... OUTCOME MEASURES: Best-corrected VA and primary causes of visual impairment. RESULTS: The prevalence of low vision according to the WHO definition ranged from 2.6% in subjects aged 70 to 74 years to 4.8% in subjects 75 to 80 years of age, with an age-adjusted relative prevalence of 1.58%. Using the U...

  7. Iodine nutritional status and goiter prevalence in primary school children aged 6-12 of Panchmahal district, Gujarat, India

    Directory of Open Access Journals (Sweden)

    Vihang Mazumdar

    2010-06-01

    Full Text Available Introduction: Iodine deficiency disorders (IDD create major public health problems in India, including Gujarat. Panchmahal district is known for endemic iodine deficiency. The present study was conducted to (1 estimate the prevalence of goiter in primary school children, (2 determine median urinary iodine concentration, (3 assess the level of iodine in salt samples at the household and retail shop level, and (4 profile of salt sold at retail shops in Panchmahal district, Gujarat. Methods: A total of 70 students including five boys and five girls from 1st to 7th standard who were present on the day of the first visit were selected randomly for goiter examination from each village. Urine samples were collected from one boy and one girl from each standard in each cluster. From the community, at least 28 students, including two boys and two girls from each standard in the same age group, were examined, and salt samples were tested from their households. A total of 2100 students were examined in schools and 928 students were examined in the selected villages. From each village, one retail shop was visited, and salts purchased from those shops were immediately tested for iodine with spot kits.Results: Among young primary school children, goiter prevalence was 23.35% (grade 1—18.35%, grade 2—5.0%. As the ages increase, goiter prevalence also increases except for 9-year-olds. The median urinary iodine excretion level was 110 µg/L. An iodine level >15 ppm was found in 78.3% of the salt samples tested at household level. Conclusion: The present study showed considerable goiter prevalence in primary school children in Panchmahal district of Gujarat and an inadequate iodine content of salt at the household level.

  8. Epilepsy Prevalence in the 0-17 Age Group in Trabzon, Turkey

    Directory of Open Access Journals (Sweden)

    Murat Topbaş

    2012-09-01

    Full Text Available Objective: Epilepsy is a most common serious neurological disorder and is one of the world’s most prevalent non-communicable diseases. The aim of this study was to determine the prevalence and risk factors of epilepsy in 0–17 year old children in Trabzon, Turkey.Methods: A cross-sectional epidemiological investigation was performed in two phases, a screening phase and a confirmation of the diagnosis phase. The gold standard was a clinical investigation and neurological examination. The diagnosis of epilepsy followed clinical guidelines proposed by the International League against Epilepsy (ILAE. The chi-square test was used in analysis of the results and P-value <0.05 was calculated.Findings: The prevalence per 1000 participants of epilepsy was 8.6 (5.9–11.4; 95%CI. We detected 37 cases(18 males and 19 females of epilepsy. The male/female ratio was 0.95. This study showed an increased risk for epilepsy with low socioeconomic level, a history of postpartum seizure, meningitis, head trauma, febrile convulsion and family history of epilepsy. More than one seizure type was present in 15 (40.5% of epileptic children. Generalized tonic-clonic seizures were determined in 24 patients (64.9% and absence type in 9 (24.3%. It was found that 25.0% of children with epilepsy had never visited the school at the time the study was performed due to the disease and attendant seizures.Conclusion: The prevalence of epilepsy in Trabzon is low compared to other parts of Turkey and other developing countries.

  9. Generalized Linear Covariance Analysis

    Science.gov (United States)

    Carpenter, James R.; Markley, F. Landis

    2014-01-01

    This talk presents a comprehensive approach to filter modeling for generalized covariance analysis of both batch least-squares and sequential estimators. We review and extend in two directions the results of prior work that allowed for partitioning of the state space into solve-for'' and consider'' parameters, accounted for differences between the formal values and the true values of the measurement noise, process noise, and textita priori solve-for and consider covariances, and explicitly partitioned the errors into subspaces containing only the influence of the measurement noise, process noise, and solve-for and consider covariances. In this work, we explicitly add sensitivity analysis to this prior work, and relax an implicit assumption that the batch estimator's epoch time occurs prior to the definitive span. We also apply the method to an integrated orbit and attitude problem, in which gyro and accelerometer errors, though not estimated, influence the orbit determination performance. We illustrate our results using two graphical presentations, which we call the variance sandpile'' and the sensitivity mosaic,'' and we compare the linear covariance results to confidence intervals associated with ensemble statistics from a Monte Carlo analysis.

  10. Prevalence of diminished kidney function in a representative sample of middle and older age adults in the Irish population

    Directory of Open Access Journals (Sweden)

    Browne Gemma M

    2012-11-01

    Full Text Available Abstract Background The prevalence of chronic kidney disease (CKD using available estimating equations with the Republic of Ireland is unknown. Methods A randomly selected population based cross-sectional study of 1,098 adults aged 45 years and older was conducted using data from the 2007 Survey of Lifestyle, Attitudes and Nutrition (SLÁN. Estimated Glomerular Filtration Rate (eGFR was calculated from a single IDMS aligned serum creatinine using the CKD-EPI and the MDRD equations, and albumin to creatinine ratio was based on a single random urine sample. Results The sample clinical characteristics and demography was similar to middle and older age adults in the general Irish population, though with an underrepresentation of subjects >75 years and of males. All results are based on subjects with available blood and urine samples. Applying weighting to obtain survey based population estimates, using Irish population census data, the estimated weighted prevalence of CKD-EPI eGFR2 was 11.6%, (95% confidence interval; 9.0, 14.2%, 12.0% ( 9.0, 14.2% of men and 11.2% (7.3, 15.2% of women. Unweighted prevalence estimates were similar at 11.8% (9.9, 13.8%. Albuminuria increased with lower CKD-EPI eGFR category. 10.1% of all subjects had albuminuria and an eGFR≥60 mL/min/1.73 m2 giving an overall weighted estimated prevalence of National Kidney Foundation (NKF defined CKD 21.3% (18.0, 24.6%, with the unadjusted estimate of 21.9% (19.5, 24.4%. MDRD related estimates for eGFR 2, and NFK defined CKD were higher than CKD-EPI and differences were greater in younger and female subjects. Conclusions CKD is highly prevalent in middle and older aged adults within the Republic of Ireland. In this population, there is poor agreement between CKD-EPI and MDRD equations especially at higher GFRs. CKD is associated with lower educational status and poor self rated health.

  11. Age-Related Decline and Diagnostic Performance of More and Less Prevalent Clinical Cases

    Science.gov (United States)

    St-Onge, Christina; Landry, Marjolaine; Xhignesse, Marianne; Voyer, Gilles; Tremblay-Lavoie, Stéphanie; Mamede, Sílvia; Schmidt, Henk; Rikers, Remy

    2016-01-01

    Since cognitive abilities have been shown to decrease with age, it is expected that older physicians would not perform as well as their younger counterparts on clinical cases unless their expertise can counteract the cognitive effects of aging. However, studies on the topic have shown contradictory results. This study aimed to further investigate…

  12. Prevalence and associated factors of diabetes and impaired fasting glucose in Chinese hypertensive adults aged 45 to 75 years.

    Directory of Open Access Journals (Sweden)

    Xianhui Qin

    Full Text Available OBJECTIVE: This study examined the prevalence of impaired fasting glucose (IFG and diabetes and their associated factors in 17,184 Chinese hypertensive adults aged 45-75 years. METHODS: A cross-sectional investigation was carried out in a rural area of Lianyungang, China. Previously undiagnosed diabetes [fasting plasma glucose (FPG ≥ 7.0 mmol/l] and IFG (6.1-6.9 mmol/l were defined based on FPG concentration. Previously diagnosed diabetes was determined on the basis of self-report. Total diabetes included both previously diagnosed diabetes and previously undiagnosed diabetes. RESULTS: The prevalence of previously diagnosed diabetes, undiagnosed diabetes, and IFG were 3.4%, 9.8%, and 14.1%, respectively. About 74.2% of the participants with diabetes had not previously been diagnosed. In the multivariable logistic-regression model, older age, men, antihypertensive treatment, obesity (BMI ≥ 25 kg/m(2, abdominal obesity (waist circumference ≥ 90 cm for men and ≥ 80 cm for women, non-current smoking, a family history of diabetes, higher heart rate, lower physical activity levels, and inland residence (versus coastal were significantly associated with both total diabetes and previously undiagnosed diabetes. Furthermore, methylene- tetrahydrofolate reductase (MTHFR 677 TT genotype was an independent associated factor for total diabetes, and current alcohol drinking was an independent associated factor for previously undiagnosed diabetes. At the same time, older age, men, abdominal obesity, non-current smoking, current alcohol drinking, a family history of diabetes, higher heart rate, and inland residence (versus coastal were important independent associated factors for IFG. CONCLUSION: In conclusion, we found a high prevalence of diabetes in Chinese hypertensive adults. Furthermore, about three out of every four diabetic adults were undiagnosed. Our results suggest that population-level measures aimed at the prevention, identification (even if

  13. Prevalence of thinness among the adolescent girls (age group 13yrs-18yrs of Garhkhal Village of Himachal Pradesh, India.

    Directory of Open Access Journals (Sweden)

    Priyanka Rani Garg

    2011-08-01

    Full Text Available Normal 0 false false false EN-US X-NONE X-NONE /* Style Definitions */ table.MsoNormalTable {mso-style-name:"Normal Tablo"; mso-tstyle-rowband-size:0; mso-tstyle-colband-size:0; mso-style-noshow:yes; mso-style-priority:99; mso-style-qformat:yes; mso-style-parent:""; mso-padding-alt:0in 5.4pt 0in 5.4pt; mso-para-margin:0in; mso-para-margin-bottom:.0001pt; mso-pagination:widow-orphan; font-size:10.0pt; font-family:"Calibri","sans-serif"; mso-bidi-font-family:"Times New Roman";} Malnutrition has now been redefined in terms of “under nutrition” and conceptualized in terms of thinness which is an important problem among children and adolescents in rural areas of developing countries like India. Therefore, present study was carried out to assess the prevalence of thinness among the adolescent girls (age group 13yrs-18yrs of Garhkhal Village of Himachal Pradesh, India. The study design was cross-sectional. Height and weight were measured and Body Mass Index (BMI was carried out. Identification of thinness was done according to the new International BMI-based classification cut offs as given by Cole et al., 2007. In general the mean BMI increased with increasing age. Overall age-combined prevalence was 79.5%. Present study indicated the poor health status of the adolescent girls of the selected area which indicates the high nutritional stress among them as evident from the thinness prevalent among them.

  14. Prevalence and Diversity of Salmonella Serotypes in Ecuadorian Broilers at Slaughter Age

    Science.gov (United States)

    Cevallos, María; Ron-Garrido, Lenin; Bertrand, Sophie; De Zutter, Lieven

    2016-01-01

    Salmonella is frequently found in poultry and represent an important source for human gastrointestinal infections worldwide. The aim of this study was to investigate the prevalence, genotypes and antimicrobial resistance of Salmonella serotypes in broilers from Ecuador. Caeca content from 388 at random selected broiler batches were collected in 6 slaughterhouses during 1 year and analyzed by the ISO 6579/Amd1 protocol for the isolation for Salmonella. Isolates were serotyped and genotypic variation was acceded by pulsed field gel electrophoresis. MIC values for sulfamethoxazole, gentamicin, ciprofloxacin, ampicillin, cefotaxime, ceftazidime, tetracycline, streptomycin, trimethropim, chloramphenicol, colistin, florfenicol, kanamycin and nalidixic acid were obtained. Presence of blaCTX-M, blaTEM, blaSHV and blaCMY; and mcr-1 plasmid genes was investigated in resistant strains to cefotaxime and colistin respectively. Prevalence at batch level was 16.0%. The most common serotype was S. Infantis (83.9%) followed by S. Enteritidis (14.5%) and S. Corvallis (1.6%). The pulsed field gel electrophoresis analysis showed that S. Corvallis, S. Enteritidis and S. Infantis isolates belonged to 1, 2 and 12 genotypes respectively. S. Infantis isolates showed high resistance rates to 12 antibiotics ranging from 57.7% (kanamycin) up to 98.1% (nalidixic acid and sulfamethoxazole). All S. Enteritidis isolates showed resistance to colistin. High multiresistant patterns were found for all the serotypes. The blaCTX-M gene was present in 33 S. Infantis isolates while mcr-1 was negative in 10 colistin resistant isolates. This study provides the first set of scientific data on prevalence and multidrug-resistant Salmonella coming from commercial poultry in Ecuador. PMID:27414038

  15. Prevalence of Frailty and Aging-Related Health Conditions in Older Koreans in Rural Communities: a Cross-Sectional Analysis of the Aging Study of Pyeongchang Rural Area.

    Science.gov (United States)

    Jung, Hee-Won; Jang, Il-Young; Lee, Young Soo; Lee, Chang Ki; Cho, Eun-Il; Kang, Woo Young; Chae, Jeoung Hee; Lee, Eun Ju; Kim, Dae Hyun

    2016-03-01

    Frailty has been previously studied in Western countries and the urban Korean population; however, the burden of frailty and geriatric conditions in the aging populations of rural Korean communities had not yet been determined. Thus, we established a population-based prospective study of adults aged ≥ 65 years residing in rural communities of Korea between October 2014 and December 2014. All participants underwent comprehensive geriatric assessment that encompassed the assessment of cognitive and physical function, depression, nutrition, and body composition using bioimpedance analysis. We determined the prevalence of frailty based on the Cardiovascular Health Study (CHS) and Korean version of FRAIL (K-FRAIL) criteria, as well as geriatric conditions. We recruited 382 adults (98% of eligible adults; mean age: 74 years; 56% women). Generally, sociodemographic characteristics were similar to those of the general rural Korean population. Common geriatric conditions included instrumental activity of daily living disability (39%), malnutrition risk (38%), cognitive dysfunction (33%), multimorbidity (32%), and sarcopenia (28%), while dismobility (8%), incontinence (8%), and polypharmacy (3%) were less common conditions. While more individuals were classified as frail according to the K-FRAIL criteria (27%) than the CHS criteria (17%), the CHS criteria were more strongly associated with prevalent geriatric conditions. Older Koreans living in rural communities have a significant burden of frailty and geriatric conditions that increase the risk of functional decline, poor quality of life, and mortality. The current study provides a basis to guide public health professionals and policy-makers in prioritizing certain areas of care and designing effective public health interventions to promote healthy aging of this vulnerable population. PMID:26952571

  16. Covariates of Sesame Street Viewing by Preschoolers.

    Science.gov (United States)

    Spaner, Steven D.

    A study was made of nine covariates as to their discriminating power between preschoolers who watch Sesame Street regularly and preschoolers who do not watch Sesame Street, Surveyed were 372 3-4 year old children on 9 variables. The nine variables were: race, socioeconomic status, number of siblings, child's birth order, maternal age, maternal…

  17. Gestational diabetes mellitus results in a higher prevalence of small for gestational age babies

    LENUS (Irish Health Repository)

    Avalos, G

    2011-09-01

    Background and aims: Gestational Diabetes Mellitus (GDM) is associated with increased foetal and maternal morbidity and mortality. Previous studies have shown that babies of diabetic mothers are more likely to be large for gestational age (LGA). This retrospective study aimed to assess whether the converse may also be true, that there may also a higher rate of small for gestational age (SGA) amongst babies of mothers with GDM.\\r\

  18. Prevalence of Age-Related Changes in Ovine Lumbar Intervertebral Discs during Computed Tomography and Magnetic Resonance Imaging.

    Science.gov (United States)

    Nisolle, Jean-François; Bihin, Benoît; Kirschvink, Nathalie; Neveu, Fabienne; Clegg, Peter; Dugdale, Alexandra; Wang, Xiaoqing; Vandeweerd, Jean-Michel

    2016-01-01

    Ovine models are used to study intervertebral disc (IVD) degeneration. The objective of the current study was to assess the naturally occurring age-related changes of the IVD that can be diagnosed by CT and MRI in the lumbar spine of sheep. We used CT and T2-weighted MR images to score the IVD (L6S1 to L1L2) in 41 sheep (age, 6 mo to 11 y) that were euthanized for reasons not related to musculoskeletal disease. T2 mapping and measurement of T2 time of L6S1 to L2L3 were performed in 22 of the sheep. Degenerative changes manifested as early as 2 y of age and occurred at every IVD level. Discs were more severely damaged in older sheep. The age effect of the L6S1 IVD was larger than the average age effect for the other IVD. The current study provides evidence that lesions similar to those encountered in humans can be identified by CT and MRI in lumbar spine of sheep. Ideally, research animals should be assessed at the initiation of preclinical trials to determine the extent of prevalent degenerative changes. The ovine lumbosacral disc seems particularly prone to degeneration and might be a favorable anatomic site for studying IVD degeneration.

  19. Prevalence of Age-Related Changes in Ovine Lumbar Intervertebral Discs during Computed Tomography and Magnetic Resonance Imaging.

    Science.gov (United States)

    Nisolle, Jean-François; Bihin, Benoît; Kirschvink, Nathalie; Neveu, Fabienne; Clegg, Peter; Dugdale, Alexandra; Wang, Xiaoqing; Vandeweerd, Jean-Michel

    2016-01-01

    Ovine models are used to study intervertebral disc (IVD) degeneration. The objective of the current study was to assess the naturally occurring age-related changes of the IVD that can be diagnosed by CT and MRI in the lumbar spine of sheep. We used CT and T2-weighted MR images to score the IVD (L6S1 to L1L2) in 41 sheep (age, 6 mo to 11 y) that were euthanized for reasons not related to musculoskeletal disease. T2 mapping and measurement of T2 time of L6S1 to L2L3 were performed in 22 of the sheep. Degenerative changes manifested as early as 2 y of age and occurred at every IVD level. Discs were more severely damaged in older sheep. The age effect of the L6S1 IVD was larger than the average age effect for the other IVD. The current study provides evidence that lesions similar to those encountered in humans can be identified by CT and MRI in lumbar spine of sheep. Ideally, research animals should be assessed at the initiation of preclinical trials to determine the extent of prevalent degenerative changes. The ovine lumbosacral disc seems particularly prone to degeneration and might be a favorable anatomic site for studying IVD degeneration. PMID:27538861

  20. Using Analysis of Covariance (ANCOVA) with Fallible Covariates

    Science.gov (United States)

    Culpepper, Steven Andrew; Aguinis, Herman

    2011-01-01

    Analysis of covariance (ANCOVA) is used widely in psychological research implementing nonexperimental designs. However, when covariates are fallible (i.e., measured with error), which is the norm, researchers must choose from among 3 inadequate courses of action: (a) know that the assumption that covariates are perfectly reliable is violated but…

  1. Prevalence and Determinants of Vaginal Discharge among Women of Reproductive Age Group in Tertiary Care Hospital of Northern India

    Directory of Open Access Journals (Sweden)

    Varsha Chaudhary, Rajeev Kumar, Vijender K Agrawal, Arun Singh, Ramesh Narula, Mahendra Sharma

    2012-01-01

    Full Text Available Background: The complaint of vaginal discharge is very common, particularly in south East Asia it is associated with considerable disability, health seeking, and associated costs. Objective: To estimate the hospital based prevalence of vaginal discharge, to find out socio-demographic variables associated with the complaint of vaginal discharge, perceived causes of vaginal discharge and association of vaginal discharge with other gynaecological problems among the women of reproductive age. Methods: The present cross sectional study was conducted in one of the tertiary care hospital of Bareilly district. The respondent were the female in reproductive age group (15-49yrs attending Obst. & gynae OPD. Sample size of 590 was calculated, for sample to be more representative of population, a total of 1100 female in reproductive age group were included in the study. . Odds ratio (OR and their 95% confidence interval (CI were calculated to estimate the strength of association between vaginal discharge and other gynaecological symptoms. Chi square test was applied as test of significance for data analysis. Results: Prevalence of vaginal discharge was found to be 24.6%. Factors like increasing age, married (26.2%, illiteracy (60.1%, Muslim religion (28.7%, low socioeconomic status, high parity, history of induced abortion and place of delivery were found to be significantly associated with vaginal discharge. Internal gynaecological problem was perceived as a main cause for vaginal discharge (73.3%. Vaginal discharge was found to be significantly associated with other gynaecological problems. Recommendation: There is need for creating community awareness about health care facilities and instills self concern in women for their own health needs.

  2. Age, gender and normalization covariates for spinal cord gray matter and total cross-sectional areas at cervical and thoracic levels: A 2D phase sensitive inversion recovery imaging study.

    Directory of Open Access Journals (Sweden)

    Nico Papinutto

    Full Text Available The source of inter-subject variability and the influence of age and gender on morphometric characteristics of the spinal cord, such as the total cross-sectional area (TCA, the gray matter (GM and white matter (WM areas, currently remain under investigation. Understanding the effect of covariates such as age, gender, brain volumes, and skull- and vertebra-derived metrics on cervical and thoracic spinal cord TCA and GM areas in healthy subjects would be fundamental for exploring compartment specific changes in neurological diseases affecting the spinal cord. Using Magnetic Resonance Imaging at 3T we investigated 32 healthy subjects using a 2D phase sensitive inversion recovery sequence and we measured TCA, GM and WM areas at 4 cervical and thoracic levels of the spinal cord. We assessed age and gender relationships of cord measures and explored associations between cord measures and a brain volumes and b skull- and vertebra-derived metrics. Age and gender had a significant effect on TCA, WM and GM areas (with women and elderly having smaller values than men and younger people respectively, but not on the GM area/TCA ratio. The total intracranial volume and C3 vertebra dimensions showed the highest correlations with cord measures. When used in multi-regression models, they reduced cord areas group variability by approximately a third. Age and gender influences on cord measures and normalization strategies here presented might be of use in the study of compartment specific changes in various neurological diseases affecting the spinal cord.

  3. Prevalence of anaemia and associated factors among children below five years of age in Cape Verde, West Africa.

    Science.gov (United States)

    Semedo, Rosa M L; Santos, Marta M A S; Baião, Mirian R; Luiz, Ronir R; da Veiga, Gloria V

    2014-12-01

    This study estimated the prevalence of anaemia and associated factors in a probability sample of 993 chil- dren aged 6-59 months in Cape Verde, West Africa. Odds ratio (OR) and 95% confidence interval (95% CI) were estimated from a hierarchical model for multiple analysis to assess the association between anaemia and explanatory variables. The prevalence of anaemia was 51.8% (95% CI 47.7-55.8). Children who resided within poor household conditions (OR 1.99; 95% CI 1.06-3.71) were below 24 months of age (OR 3.23; 95% CI 2.03-5.15) and recently experienced diarrhoea (OR 1.58; 95% CI 0.99-2.50) were at high risk of anaemia. Anaemia should be considered a serious public-health concern in Cape Verde, mainly for chil- dren below 24 months. Further, special consideration should be given to children who have experienced recent diarrhoea and belong to families residing in poor household conditions. PMID:25895198

  4. Prevalence of Overweight and Obesity among Primary School Children Aged 8–13 Years in Dar es Salaam City, Tanzania

    Science.gov (United States)

    Pangani, Ismail N.; Kiplamai, Festus K.; Kamau, Jane W.; Onywera, Vincent O.

    2016-01-01

    Background. The understanding of obesity as a growing health problem in Africa and Tanzania in particular is hampered by lack of data as well as sociocultural beliefs in which overweight and obesity are revered. This study sought to determine the prevalence of overweight and obesity among primary school children aged 8–13 years in Dar es Salaam, Tanzania. Method. A cross-sectional analytical research design was used to study overweight and obesity in primary schools in Dar es Salaam, Tanzania. The target population was 150,000 children aged 8–13 years. Stratified random sampling was used to select 1781 children. Weight and height were taken and WHO standards for children were used to determine weight status. Results. Findings showed that the prevalence of overweight and obesity was 15.9% and 6.7%, respectively (N = 1781). However, 6.2% of the children were underweight. There were significant differences in mean BMI between children in private and public schools (p = 0.021), between male and female (p obesity among primary school children is significant and requires management and prevention strategies.

  5. The Prevalence of Anxiety and its related Factors among School-age Children in South West of Iran

    Directory of Open Access Journals (Sweden)

    Zeinab Banaeipour

    2016-06-01

    Full Text Available Background Anxiety is one of the most common childhood disorders, so it is necessary to explore extend and its related factors in the students. This study was conducted to determine the prevalence of anxiety and the related factors of anxiety among the children aged 9-12 years. Materials and Methods At a descriptive-analytic study 623 children aged 9-12 year- old who were studying in the fourth to sixth grade of elementary school in Dezful city, were selected through multistage random sampling.  The data were collected using demographic profile questionnaire and School Anxiety Scale (SAS using SPSS-16. Results Of total 623 students, 36.3% were girls. 232 (37.2% students had mild anxiety, 304 students (48.8% had moderate anxiety and 87 students (14% had severe anxiety. There was a significant relationship between the mean score of children anxiety and the number of children in family (P0.0.5. Conclusion This study showed that the prevalence of anxiety was higher in boyes, children who were single children, children who had a family history of hereditary disease, and children who experienced corporal punishment at home. It is recommended arranging programs including training, counseling, and psychotherapy ones for these children and their families.

  6. Prevalence of and Susceptibility to Cigarette Smoking Among Female Students Aged 13 to 15 Years in Vietnam, 2007

    Directory of Open Access Journals (Sweden)

    Hoang Van Minh, MD, PhD

    2010-01-01

    Full Text Available IntroductionRecent reports show a sharp increase in smoking rates among girls. We describe prevalence of cigarette smoking and susceptibility to cigarette smoking among female students aged 13 to 15 years in Vietnam and examine the associated factors.MethodsWe used data from female secondary school students aged 13 to 15 years (grades 8-10 from the 2007 Global Youth Tobacco Survey that was conducted in 9 provinces in Vietnam. We used multivariate logistic regression analysis to determine associations between independent variables with smoking status and susceptibility to smoking.ResultsPrevalence of cigarette smoking among girls was 1.2% (95% confidence interval [CI], 0.9-1.5, and 1.5% (95% CI, 1.2-1.9 of girls were susceptible to smoking. Having friends who smoke was the strongest predictor of both smoking status and susceptibility to smoking. Attendance at school classes that described the harmful effects of smoking had significant effects in reducing cigarette smoking. Girls who were exposed to billboard cigarette advertising were more likely to be susceptible to smoking than were those who had not seen advertisements.ConclusionOur findings highlight the need for pursuing school-based intervention programs in Vietnam and for countering tobacco advertising and marketing practices that target young women.

  7. Prevalence of anemia in children 1 to 12 years of age: results from a nationwide probabilistic survey in Mexico

    Directory of Open Access Journals (Sweden)

    Villalpando Salvador

    2003-01-01

    Full Text Available OBJECTIVE: To describe the epidemiology and analyze factors associated with iron deficiency anemia in a probabilistic sample of the Encuesta Nacional de Nutrición 1999 (ENN-99 [National Nutritional Survey 1999 (NNS-99]. MATERIAL AND METHODS: The sample included 8 111 children aged 1 to 12 years, and was nationaly representative by rural and urban strata and by four geographical regions. Capillary hemoglobin was measured using a portable photometer (HemoCue. The analysis of the determining factors of anemia was performed by odds ratios derived from a logistic regression model and multiple regression models. RESULTS: The prevalence of anemia was 50% in infants <2 years of age, with no significant differences between urban and rural strata or among regions. It varied between 14 and 22% in 6-11 year-old children and was higher in the South region and among the indigenous children. Dietary intake of iron was 50% of the recommended daily allowance in children <2 years of age, but not in older children. Phytate (»500-800 mg/d and tannin (»19 mg/d intakes were very high in children over 7 years of age. Hemoglobin was positively associated with nutritional status of children (p=0.01, socioeconomic status (p range 0.05-0.001, duration of lactation in children under 2 years of age (p=0.1, and iron and calcium intake (p=0.02, but not with folic acid or vitamin B12 intake. Hemoglobin was negatively associated with maternal education (p=0.01 in older children, but not in those under 2 years of age. CONCLUSIONS: We present evidence of an alarming national epidemic of anemia, particularly marked in children 12 to 24 months of age. The control of anemia should be considered as an urgent national concern given its grave consequences on the physical and mental development of these children and on their long-term health.

  8. Prevalence, Vascular Distribution, and Multiterritorial Extent of Subclinical Atherosclerosis in a Middle-Aged Cohort

    DEFF Research Database (Denmark)

    Fernández-Friera, Leticia; Peñalvo, José L; Fernández-Ortiz, Antonio;

    2015-01-01

    BACKGROUND: Data are limited on the presence, distribution, and extent of subclinical atherosclerosis in middle-aged populations. METHODS AND RESULTS: The PESA (Progression of Early Subclinical Atherosclerosis) study prospectively enrolled 4184 asymptomatic participants 40 to 54 years of age (mean...... age, 45.8 years; 63% male) to evaluate the systemic extent of atherosclerosis in the carotid, abdominal aortic, and iliofemoral territories by 2-/3-dimensional ultrasound and coronary artery calcification by computed tomography. The extent of subclinical atherosclerosis, defined as presence of plaque...... or coronary artery calcification ≥1, was classified as focal (1 site affected), intermediate (2-3 sites), or generalized (4-6 sites) after exploration of each vascular site (right/left carotids, aorta, right/left iliofemorals, and coronary arteries). Subclinical atherosclerosis was present in 63...

  9. The Prevalence of Helicobacter pylori Infection Decreases with Older Age in Atrophic Gastritis

    Directory of Open Access Journals (Sweden)

    Shaohua Chen

    2013-01-01

    Full Text Available The clinical pathological characteristics of 3969 adult patients with chronic atrophic gastritis were retrospectively studied. The positivity of intestinal metaplasia and dysplasia in atrophic gastric specimens increased with age; however, H. pylori positivity and inflammatory activity decreased significantly with increased age. H. pylori infection was present in 21.01% of chronic atrophic gastritis patients, and 92.33% of the subjects with H. pylori infection were found to have simultaneous inflammatory activity. The intestinal metaplasia and dysplasia positivity markedly increased as the degree of gastric atrophy increased. In conclusion, the incidence of H. pylori infection decreased with age and correlated significantly with inflammatory activity in atrophic gastritis patients. The intestinal metaplasia and dysplasia positivity notably increased as the degree of gastric atrophy increased. Large population-based prospective studies are needed to better understand the progression of CAG.

  10. Prevalence of dry eye amongst black and Indian university students aged 18–30 years

    Directory of Open Access Journals (Sweden)

    Bryce Castelyn

    2015-03-01

    Full Text Available Background: The overall prevalence of dry eye in South Africa seems to be increasing. University students work under conditions predisposing them to dry eye, which may affect some tasks. The predominant race groups at the University of KwaZulu-Natal (UKZN are black and Indian, which suggested a study in this student population to assist the diagnosis and management of such subjects.Aim and setting: To compare the prevalence of dry eye amongst black and Indian students at the UKZN’s Westville campus.Methods: One hundred participants, equally divided by gender and race, between 18 and 30 years old were enrolled. Dry eye symptoms were investigated by the ocular surface disease index (OSDI, tear thinning time (TTT, tear breakup time (TBUT and Schirmer’s 2 in that sequence on both eyes of each participant.Results: The OSDI revealed that 41% of participants had some dry eye symptoms whilst 59% had no symptoms. Clinical testing showed that 81% of participants had dry eye. Half of the black participants had dry eye symptoms and 82% had clinical signs of dry eye. Of the 50 Indian participants, 32% had dry eye symptoms and 80% had clinical signs. Of the 50 male participants, 34% were symptomatic and 86% had clinical signs. Of the 50 female participants, 48% had dry eye symptoms and 76% had clinical signs. Participants were asymptomatic even in the presence of clinical dry eye signs.Conclusion: For both races and genders, clinical signs of dry eye were more common than symptoms. Black participants were more likely to report symptoms than Indians, and more women than men reported having symptoms. Male participants were more likely than female to have clinical signs of dry eye.

  11. Clinical characteristics and prevalence of vitamin D insufficiency in children less than two years of age

    OpenAIRE

    Yoon, Ji Hyun; Park, Cheong Soo; Seo, Ji Young; Choi, Yun Sun; AHN, YOUNG MIN

    2011-01-01

    Purpose To evaluate the clinical characteristics of vitamin D deficiency and its association with iron deficiency anemia (IDA). Methods A total of 171 children aged less than two years underwent 25-hydroxyvitamin D3 tests between January 2007 and July 2009. The study was classified into two groups: normal and vitamin D insufficiency, by their vitamin 25-hydroxyvitamin D3 levels. Results In total, 120 children were in the normal group (mean age, body weight and heights 12.5±7.0, 9.3±0.9 kg and...

  12. Covariate-adjusted measures of discrimination for survival data

    DEFF Research Database (Denmark)

    White, Ian R; Rapsomaniki, Eleni; Frikke-Schmidt, Ruth

    2015-01-01

    MOTIVATION: Discrimination statistics describe the ability of a survival model to assign higher risks to individuals who experience earlier events: examples are Harrell's C-index and Royston and Sauerbrei's D, which we call the D-index. Prognostic covariates whose distributions are controlled...... statistics in censored survival data. OBJECTIVE: To develop extensions of the C-index and D-index that describe the prognostic ability of a model adjusted for one or more covariate(s). METHOD: We define a covariate-adjusted C-index and D-index for censored survival data, propose several estimators...... by the study design (e.g. age and sex) influence discrimination and can make it difficult to compare model discrimination between studies. Although covariate adjustment is a standard procedure for quantifying disease-risk factor associations, there are no covariate adjustment methods for discrimination...

  13. Lifetime Prevalence, Age of Risk, and Genetic Relationships of Comorbid Psychiatric Disorders in Tourette Syndrome

    NARCIS (Netherlands)

    Hirschtritt, Matthew E; Lee, Paul C; Pauls, David L; Dion, Yves; Grados, Marco A; Illmann, Cornelia; King, Robert A; Sandor, Paul; McMahon, William M; Lyon, Gholson J; Cath, Danielle C; Kurlan, Roger; Robertson, Mary M; Osiecki, Lisa; Scharf, Jeremiah M; Mathews, Carol A

    2015-01-01

    IMPORTANCE: Tourette syndrome (TS) is characterized by high rates of psychiatric comorbidity; however, few studies have fully characterized these comorbidities. Furthermore, most studies have included relatively few participants (<200), and none has examined the ages of highest risk for each TS-asso

  14. Prevalence of meningococcal carriage in children and adolescents aged 10-19 years in Chile in 2013.

    Science.gov (United States)

    Díaz, Janepsy; Cárcamo, Marcela; Seoane, Mabel; Pidal, Paola; Cavada, Gabriel; Puentes, Rodrigo; Terrazas, Solana; Araya, Pamela; Ibarz-Pavon, Ana B; Manríquez, Macarena; Hormazábal, Juan C; Ayala, Salvador; Valenzuela, María T

    2016-01-01

    In 2011, Chile experienced an increase in the number of cases of IMD caused by Neisseria meningitidis group W. This epidemiological scenario prompted authorities to implement prevention strategies. As part of these strategies, the Institute of Public Heath of Chile conducted a cross-sectional study to determine the prevalence of pharyngeal carriage of N. meningitidis in a representative sample of healthy children and adolescents aged 10-19 years. The identification of presumptive N. meningitidis strains was performed by testing carbohydrate utilization in the National Reference Laboratory at the ISP. Association of meningococcal carriage with risk factors was analyzed by calculating the Odds Ratio. Selected variables were included in a logistic model for risk analyses. The prevalence of carriage of N. meningitidis was 6.5% (CI: 5.7-7.3%). Older age (carriers: 14.2±0.29 vs. non-carriers: 13.8±0.08 years old; p=0.009), cohabitation with children (carriers: 0.9±0.13 vs. non-carriers: 0.7±0.03; p=0.028), number of smoking cohabitants (carriers: 0.55±0.13 vs. non-carriers: 0.44±0.03) and frequent attendance to crowded social venues (carriers: 49% vs. non-carriers: 37%; p=0.008) were determined to favor carriage. Statistical modeling showed that meningococcal carriage was associated with older age (OR: 1.077, p-value: 0.002) and cohabitation with children (OR: 1.182, p-value: 0.02). PMID:26819097

  15. Influence of age on prevalence rates of chronic complications of hospitalized aged patients with hypertension——analysis of 17,682 cases

    Institute of Scientific and Technical Information of China (English)

    Hua Cui; Yixin Hu; Li Fan; Guoliang Hu; Wei Dai

    2009-01-01

    Objective To understand the relationship between age and chronic complications in hospitalized aged patients with hypertension, to provide evidence for hypertension prevention and control. Methods To retrospectively analyze the clinical and laboratory data on 17,682 patients with essential hypertension during Jan 1st,1993-Dee 12th, 2008 in PLA general hospital. Results 1)Among all of the inrolled cases, those aged 60-64 account for 27.87%, 65-69 years group account for 26.55%, 70-74 years group accounted for 23.96%, 75-79 years group accounted for 14.14%, 80-84 years group accounted for 5.26%, 85-89 years group accounted for 1.69%, > 90 years accounted for 0.41%. 2) The prevalence rate of chronic complications in 60-69 years group were 31.3-31.2% for diabetes and,22.6-27.0% for cerebrovascular disease, 9.5-11.1% for myocardial infarction, 6.7-9.1% for heart failure, 5.8-6.0% for renal dysfanction 4.9-6.8% for atrial fibrillation, 0.1-0.3% for multiple organ dysfunction syndrome (MODS) in the elderly(P <0.05 ). 3) The first four complications of hypertension were diabetes(33.5%), cerebrovascular disease (31.9%), myocardial infarction(13.2%) and heart failure(12.3%) in 70-74 years group (P<0.05), cerebrovascular disease (42.8%), diabetes (32.8%), heart failure (16.5%) and myocardial infarction(15.9%) in 75-79 years group (P<0.05), cerebrovascular disease (45.4%), diabetes (35.0%), heart failure (21.1%) and myocardial infarction(15.9%) in 80-84 years group (P<0.05), cerebrovascular disease(42.5%), diabetes (35.8%), heart failure (23.1%) and renal dysfanction (17.7%) in 85-89 years group(P<0.05 ),and cerebrovascular disease (45. 2%), heart failure(31.5%), diabetes (26.0%) and renal dysfanction (20.5%) in patients more than 90 years group (P<0.05). Conclusions The prevalence rate and kinds of chronic complications in hospitalized aged patients with hypertension were changed with the increasing age, and the first kind of complication is cerebrovascular disease. It is of

  16. Age-dependent prevalence of nasopharyngeal carriage of streptococcus pneumoniae before conjugate vaccine introduction: a prediction model based on a meta-analysis.

    Directory of Open Access Journals (Sweden)

    Olivier Le Polain de Waroux

    Full Text Available INTRODUCTION: Data on the prevalence of nasopharyngeal carriage of S.pneumoniae in all age groups are important to help predict the impact of introducing pneumococcal conjugate vaccines (PCV into routine infant immunization, given the important indirect effect of the vaccine. Yet most carriage studies are limited to children under five years of age. We here explore the association between carriage prevalence and serotype distribution in children aged ≥5 years and in adults compared to children. METHODS: We conducted a systematic review of studies providing carriage estimates across age groups in healthy populations not previously exposed to PCV, using MEDLINE and Embase. We used Bayesian linear meta-regression models to predict the overall carriage prevalence as well as the prevalence and distribution of vaccine and nonvaccine type (VT and NVT serotypes in older age groups as a function of that in <5 y olds. RESULTS: Twenty-nine studies compromising of 20,391 individuals were included in the analysis. In all studies nasopharyngeal carriage decreased with increasing age. We found a strong positive linear association between the carriage prevalence in pre-school childen (<5 y and both that in school aged children (5-17 y olds and in adults. The proportion of VT serotypes isolated from carriers was consistently lower in older age groups and on average about 73% that of children <5 y among 5-17 y olds and adults respectively. We provide a prediction model to infer the carriage prevalence and serotype distribution in 5-17 y olds and adults as a function of that in children <5 years of age. CONCLUSION: Such predictions are helpful for assessing the potential population-wide effects of vaccination programmes, e.g. via transmission models, and thus assist in the design of future pneumococcal conjugate vaccination strategies.

  17. Earth Observing System Covariance Realism

    Science.gov (United States)

    Zaidi, Waqar H.; Hejduk, Matthew D.

    2016-01-01

    The purpose of covariance realism is to properly size a primary object's covariance in order to add validity to the calculation of the probability of collision. The covariance realism technique in this paper consists of three parts: collection/calculation of definitive state estimates through orbit determination, calculation of covariance realism test statistics at each covariance propagation point, and proper assessment of those test statistics. An empirical cumulative distribution function (ECDF) Goodness-of-Fit (GOF) method is employed to determine if a covariance is properly sized by comparing the empirical distribution of Mahalanobis distance calculations to the hypothesized parent 3-DoF chi-squared distribution. To realistically size a covariance for collision probability calculations, this study uses a state noise compensation algorithm that adds process noise to the definitive epoch covariance to account for uncertainty in the force model. Process noise is added until the GOF tests pass a group significance level threshold. The results of this study indicate that when outliers attributed to persistently high or extreme levels of solar activity are removed, the aforementioned covariance realism compensation method produces a tuned covariance with up to 80 to 90% of the covariance propagation timespan passing (against a 60% minimum passing threshold) the GOF tests-a quite satisfactory and useful result.

  18. Impact of age and gender on the prevalence and prognostic importance of the metabolic syndrome and its components in Europeans. The MORGAM Prospective Cohort Project

    DEFF Research Database (Denmark)

    Vishram, Julie K; Borglykke, Anders; Andreasen, Anne H;

    2014-01-01

    OBJECTIVE: To investigate the influence of age and gender on the prevalence and cardiovascular disease (CVD) risk in Europeans presenting with the Metabolic Syndrome (MetS). METHODS: Using 36 cohorts from the MORGAM-Project with baseline between 1982-1997, 69094 men and women aged 19-78 years, wi...

  19. Mediterranean dietary pattern and prevalence and incidence of depressive symptoms in mid-aged women: results from a large community-based prospective study

    NARCIS (Netherlands)

    Rienks, J.; Dobson, A.; Mishra, G.D.

    2013-01-01

    BACKGROUND/OBJECTIVES: To investigate the association between dietary patterns and prevalence and incidence 3 years later of depressive symptoms using data from the mid-aged cohort in the Australian Longitudinal Study on Women’s Health. SUBJECTS/METHODS: Participants (aged 50–55 years) completed a f

  20. Young age of onset is associated with increased prevalence of circulating IgM rheumatoid factor and antinuclear antibodies at presentation in women with rheumatoid arthritis

    DEFF Research Database (Denmark)

    Jacobsen, Søren

    2004-01-01

    In 200 patients, 143 women and 57 men, with rheumatoid arthritis (RA), age at onset was related to the presence of IgM rheumatoid factor (RF) and antinuclear antibodies (ANA) in serum at presentation. The patients were stratified into bands of age at onset: 60 years. In women, the prevalences...... of ANA (1:160) were 63.0%, 45.5%, and 31.1% in the respective age bands ( p=0.002), and the prevalences of IgM RF were 85.2%, 72.7% and 66.4%, respectively ( p=0.03). The prevalences of ANA and IgM RF among men were, respectively, 35% and 86% with no association with age at onset. The findings may...... indicate interactive effects between gender and various pathogenetic factors....

  1. Covariant Magnetic Connection Hypersurfaces

    CERN Document Server

    Pegoraro, F

    2016-01-01

    In the single fluid, nonrelativistic, ideal-Magnetohydrodynamic (MHD) plasma description magnetic field lines play a fundamental role by defining dynamically preserved "magnetic connections" between plasma elements. Here we show how the concept of magnetic connection needs to be generalized in the case of a relativistic MHD description where we require covariance under arbitrary Lorentz transformations. This is performed by defining 2-D {\\it magnetic connection hypersurfaces} in the 4-D Minkowski space. This generalization accounts for the loss of simultaneity between spatially separated events in different frames and is expected to provide a powerful insight into the 4-D geometry of electromagnetic fields when ${\\bf E} \\cdot {\\bf B} = 0$.

  2. Universality of Covariance Matrices

    CERN Document Server

    Pillai, Natesh S

    2011-01-01

    We prove the universality of covariance matrices of the form $H_{N \\times N} = {1 \\over N} \\tp{X}X$ where $[X]_{M \\times N}$ is a rectangular matrix with independent real valued entries $[x_{ij}]$ satisfying $\\E \\,x_{ij} = 0$ and $\\E \\,x^2_{ij} = {1 \\over M}$, $N, M\\to \\infty$. Furthermore it is assumed that these entries have sub-exponential tails. We will study the asymptotics in the regime $N/M = d_N \\in (0,\\infty), \\lim_{N\\to \\infty}d_N \

  3. Covariant magnetic connection hypersurfaces

    Science.gov (United States)

    Pegoraro, F.

    2016-04-01

    > In the single fluid, non-relativistic, ideal magnetohydrodynamic (MHD) plasma description, magnetic field lines play a fundamental role by defining dynamically preserved `magnetic connections' between plasma elements. Here we show how the concept of magnetic connection needs to be generalized in the case of a relativistic MHD description where we require covariance under arbitrary Lorentz transformations. This is performed by defining 2-D magnetic connection hypersurfaces in the 4-D Minkowski space. This generalization accounts for the loss of simultaneity between spatially separated events in different frames and is expected to provide a powerful insight into the 4-D geometry of electromagnetic fields when .

  4. Covariant Projective Extensions

    Institute of Scientific and Technical Information of China (English)

    许天周; 梁洁

    2003-01-01

    @@ The theory of crossed products of C*-algebras by groups of automorphisms is a well-developed area of the theory of operator algebras. Given the importance and the success ofthat theory, it is natural to attempt to extend it to a more general situation by, for example,developing a theory of crossed products of C*-algebras by semigroups of automorphisms, or evenof endomorphisms. Indeed, in recent years a number of papers have appeared that are concernedwith such non-classicaltheories of covariance algebras, see, for instance [1-3].

  5. Prevalence of depression and its effect on disability in patients with age-related macular degeneration

    Directory of Open Access Journals (Sweden)

    Banerjee Anindya

    2008-01-01

    Full Text Available Aims: To estimate depression in patients with age-related macular degeneration (AMD and study the relationships among depression, visual acuity, and disability. Materials and Methods: It was a cross-sectional study with consecutive sampling (n = 53 of patients with AMD aged 50 years and above attending the retina clinic of a tertiary care hospital in North India. Depression, general disability and vision-specific disability were assessed in subjects meeting selection criteria. Assessments were done using the fourth edition of Diagnostic and Statistical Manual of mental disorders (DSM- IV Geriatric Depression Scale (GDS, Structured Clinical Interview for DSM-IV Axis -I Disorders, Clinical Version (SCID-CV, World Health Organization Disability Assessment Schedule-II (WHODAS-II and Daily Living Tasks dependent on Vision scale (DLTV. Non-parametric correlation analyses and regression analyses were performed. Results: Out of 53 participants, 26.4% (n = 14 met DSM-IV criteria for the diagnosis of depressive disorder. Depressed patients had significantly greater levels of general and vision-specific disability than non-depressed patients. General disability was predicted better by depression and vision-specific disability than by visual acuity. Conclusion: Depression is a major concern in patients with AMD and contributes more to disability than visual impairment.

  6. Prevalence of insomnia-related symptoms continues to increase in the Finnish working-age population.

    Science.gov (United States)

    Kronholm, Erkki; Partonen, Timo; Härmä, Mikko; Hublin, Christer; Lallukka, Tea; Peltonen, Markku; Laatikainen, Tiina

    2016-08-01

    In 2008, we published epidemiological data from 1972 to 2005 that suggested an increase in insomnia-related symptoms among the working-age population. The results were based on the National FINRISK (FR) Study samples of the Finnish adult population aged 25-64, and on the Finnish Quality of Work Life Surveys (FQWLS), carried out among Finnish salary earners. Both of these ongoing studies have since provided two new estimates of insomnia-related symptoms. Chronic insomnia-related symptoms were 9.0% (95% CI 8.3-9.7), 9.6% (95% CI 8.8-10.4) in FR 2007 and 2012, respectively; and 9.1% (95% CI 8.3-10.0), 9.2% (95% CI 8.4-10.1) in FQWLS 2008 and 2013, respectively. Occasional insomnia-related symptoms were 45.3% (95% CI 44.1-46.6), 42.5% (95% CI 41.1-43.9) in FR 2007 and 2012, respectively; and 40.3% (95% CI 38.8-41.7), 44.8% (95% CI 41.1-43.9) in FQWLS 2008 and 2013, respectively. The new estimates further strengthen the interpretation of the ongoing increase in occasional insomnia-related symptoms among the Finnish general adult population. The increase in occasional symptoms was most prominent among employees. However, chronic insomnia symptoms showed no further increase. PMID:26868677

  7. Higher prevalence of X-ray selected AGN in intermediate age galaxies up to z~1

    CERN Document Server

    Hernán-Caballero, Antonio; Pérez-González, Pablo G; Barro, Guillermo; Aird, James; Ferreras, Ignacio; Cava, Antonio; Cardiel, Nicolás; Esquej, Pilar; Gallego, Jesús; Nandra, Kirpal; Rodríguez-Zaurín, Javier

    2014-01-01

    We analyse the stellar populations in the host galaxies of 53 X-ray selected optically dull active galactic nuclei (AGN) at 0.3410^10.5 M_sun) and that the observed fraction of galaxies hosting an AGN increases with the stellar mass. A careful selection of random control samples of inactive galaxies allows us to remove the stellar mass and redshift dependencies of the AGN fraction to explore trends with several stellar age indicators. We find no significant differences in the distribution of the rest-frame U-V colour for AGN hosts and inactive galaxies, in agreement with previous results. However, we find significantly shallower 4000 AA breaks in AGN hosts, indicative of younger stellar populations. With the help of a model-independent determination of the extinction, we obtain extinction-corrected U-V colours and light-weighted average stellar ages. We find that AGN hosts have younger stellar populations and higher extinction compared to inactive galaxies with the same stellar mass and at the same redshift. ...

  8. Obesity prevalence among low-income, preschool-aged children--New York City and Los Angeles County, 2003-2011.

    Science.gov (United States)

    2013-01-18

    Recent studies have reported evidence of a leveling and decline in childhood obesity prevalence in New York and California. However, some areas of the United States continue to experience increases in the prevalence of childhood obesity. To assess differences and changes over time in early childhood obesity in the two most populous cities in the United States, obesity prevalence among low-income, preschool-aged children enrolled in the Special Supplemental Nutrition Program for Women, Infants, and Children (WIC) in New York City (NYC) was compared with obesity prevalence among WIC-enrolled children in Los Angeles County (LAC) during 2003-2011. In NYC, from 2003 to 2011, obesity prevalence decreased among blacks, whites, and Hispanics, but increased among Asians. In LAC, obesity prevalence decreased among Asians and increased and then decreased among blacks and Hispanics from 2003 to 2011. Hispanic WIC-enrolled children had the greatest prevalence of obesity for all years in both areas. In 2011, the obesity prevalence among Hispanics in NYC was 19.1%, compared with 21.7% in LAC. Comparisons of obesity prevalence data among cities and states might suggest interventions and policies to help reverse childhood obesity increases in some populations.

  9. Prevalence of coronary heart disease or stroke among workers aged <55 years--United States, 2008-2012.

    Science.gov (United States)

    Luckhaupt, Sara E; Calvert, Geoffrey M

    2014-08-01

    Cardiovascular disease accounts for one in three deaths in the United States each year, and coronary heart disease and stroke account for most of those deaths. To try to prevent 1 million heart attacks and strokes by 2017, the U.S. Department of Health and Human Services launched the Million Hearts initiative, promoting proven and effective interventions in communities and clinical settings. In workplace settings, cardiovascular disease can be addressed through a Total Worker Health program, which integrates occupational safety and health protection with health promotion. To identify workers likely to benefit from such a program, CDC analyzed data from the National Health Interview Survey (NHIS) for the period 2008-2012 to estimate the prevalence of a history of coronary heart disease or stroke (CHD/stroke) among adults aged Health approach to reducing the risk for CHD/stroke. PMID:25078653

  10. PREVALENCE AND RISK FACTORS OF HYPERTENSION AMONG ADULTS AGED 30 YEARS AND ABOVE IN A RURAL DWELLING OF KOTTAYAM, KERALA

    Directory of Open Access Journals (Sweden)

    Anand

    2014-10-01

    Full Text Available : INTRODUCTION: Rising prevalence of hypertension is a major public health challenge in India especially in Kerala. This cross sectional study was done to assess the prevalence of hypertension and its determinants in a rural population of Kottayam, Kerala. MATERIALS AND METHODS: Community based cross sectional study was carried out among 400 adults aged 30 years and above in a randomly selected ward of Ettumanoor panchayath, which is the field practice area of Govt. Medical college, Kottayam. A pretested semi structured questionnaire was used to collect information regarding socio demographic and behavioral factors. Standardized sphygmomanometric blood pressure measurement was taken by trained team members twice for each individual and the average of the two was taken as blood pressure. Anthropometric measurements were also done. A systolic blood pressure of ≥140mm of Hg and or diastolic BP≥90mm of Hg was regarded as hypertension. Data analysis was done using the software Epi-info version 3.4.3. Chi square test revealed the association between hypertension (dependent variable and other socio demographic and behavioural factors (independent variable. A p-value of <0.05 was taken as significant. All the significant variables are included in the binary logistic regression to find out Adjusted Odds Ratio (AOR RESULTS: The overall prevalence of hypertension was 35% (males-33.8% females -35.6%. The variables which evolved as significant and remained so in binary logistic regression analysis were single status after marriage/ unmarried (AOR-2.45 95% CI 1.38-4.38, low educational status (AOR- 2.31, 95%CI-1.46-3.64, family history of hypertension (AOR-1.85 95%CI-1.2-2.85 and trunkal obesity in females (AOR-2.41 95%CI-1.37-4.24 CONCLUSION: The present study revealed the prevalence (35% and risk factors for hypertension in the study area. The results of the study can be used to develop messages to make the people aware of the problem of hypertension

  11. Prevalence of premature ejaculation in young and middle-aged men in Korea: a multicenter internet-based survey from the Korean Andrological Society

    OpenAIRE

    Park, Hyun Jun; Park, Jong Kwan; Park, Kwangsung; Lee, Sung Won; Kim, Sae-Woong; Yang, Dae Yul; Moon, Du Geon; Min, Kweon-Sik; Moon, Ki-Hak; Yang, Sang-Kuk; Hyun, Jae Seog; Park, Nam Cheol

    2010-01-01

    In this study, we aimed to investigate the prevalence and perception of premature ejaculation (PE) in young and middle-aged Korean men. The study was conducted using an Internet-assisted questionnaire. A total of 2 037 Korean male adults, aged 20 years or older, were randomly sampled based on age and residency. The questionnaire developed by the PE Study Group of the Korean Andrological Society includes four categories (overall sexual function, symptoms, distress and treatment) with a total o...

  12. Prevalence of Clinical Anxiety, Clinical Depression and Associated Risk Factors in Chinese Young and Middle-Aged Patients with Osteonecrosis of the Femoral Head

    OpenAIRE

    Sheng-Bao Chen; Hai Hu; You-Shui Gao; Hai-Yan He; Dong-Xu Jin; Chang-Qing Zhang

    2015-01-01

    Objective To investigate the prevalence of clinical anxiety and clinical depression in Chinese young and mid-aged patients with osteonecrosis of the femoral head (ONFH) and to analyze their potential risk factors. Methods Two hundred and sixteen Chinese patients with ONFH were consecutively enrolled in this cross-sectional study from January 2010 to December 2010. The Zung self-rating anxiety scale (SAS) and the Zung self-rating depression scale (SDS) were used to assess the prevalence of cli...

  13. Socioeconomic status and overweight prevalence in polish adolescents: the impact of single factors and a complex index of socioeconomic status in respect to age and sex.

    Directory of Open Access Journals (Sweden)

    Joanna Kowalkowska

    2014-07-01

    Full Text Available The aim of this study was to analyze the association between overweight prevalence and socioeconomic status (SES measured by complex SES index and single SES factors in Polish adolescents in respect to age and sex.This cross-sectional study was conducted in 2010-2011. A total of 1,176 adolescents aged 13.0-18.9 years were included. The respondents were students of junior-high and high schools from northern, eastern and central Poland. Quota sampling by sex and age was used. The SES was determined by: place of residence, self-declared economic situation, and parental education level. Respondents with low, average or high SES index (SESI were identified. The level of overweight was assessed using Polish and international standards.The odds ratio (OR for overweight prevalence in the oldest girls (aged 17.0-18.9 years with high SESI was 0.34 (95%CI:0.13-0.92; P < 0.05 by Polish standards and 0.22 (95%CI:0.05-0.95; P < 0.05 by international standards, in comparison to the reference group (low SESI. In total girls who had mothers with higher education level, the OR adjusted for age was 0.44 (95%CI:0.21-0.90; P <0.05 by Polish standards and 0.35 (95%CI:0.15-0.81; P < 0.05 by international standards, in comparison to the reference group (maternal elementary education. The other single SES factors were not significant for overweight prevalence.The relationship between socioeconomic status and prevalence of overweight was related to sex and age. The high socioeconomic status strongly lowered the risk of overweight prevalence in the oldest girls, but not in boys, irrespective of age. Maternal education level lowered risk of overweight prevalence in girls.

  14. Country, age, and gender differences in the prevalence of screen-based behaviour and family-related factors among school-aged children

    Directory of Open Access Journals (Sweden)

    Jan Pavelka

    2016-09-01

    Full Text Available Background: New information and communication technologies have become an important part of adolescents' everyday lives. However, the sedentary behaviour of young people in Central Europe has become more similar to that found in Western European countries. This study can provide baseline data for a future comparison and investigation of lifestyle and health behaviours in this region in the future. Objective: The aim of this study is to assess country, age, and gender differences in the prevalence of sedentary behaviour activities and family-related factors among school-aged children. Methods: Using the methodology of the Health Behaviour in School-aged Children (HBSC study was performed in 2013, collecting data from 11- and 15-year-old Slovak (n = 488 and Czech (n = 418 children. The data was explored using c2 tests to determine statistical significance. Results: Two-thirds of the respondents watch television or use a computer for at least two hours a day. The older children (older vs. younger: 73.6% vs. 53.9%, c2 = 35.6, p < .001 spent excessive amounts of time watching television. More than half of the children have a television (51.9% or a computer (73.0% in their bedroom. More than half of their parents rarely or never apply rules about how long they can watch TV (63.9% or time spent on the computer (55.5%. The Slovak children reported watching television together with their parents every day significantly more frequently than their Czech peers (Slovak vs. Czech children 31.0% vs. 18.7%, c2 = 17.9, p < .001. Conclusions: The prevalence of screen-based behaviour is relatively high, as is screen time spent together with parents, especially among the Slovak children. Moreover, many children reported that their parents rarely or never applied rules about the length and content of their television watching or time spent on the computer.

  15. Spatial prediction of Plasmodium falciparum prevalence in Somalia

    Directory of Open Access Journals (Sweden)

    Shewchuk Tanya

    2008-08-01

    Full Text Available Abstract Background Maps of malaria distribution are vital for optimal allocation of resources for anti-malarial activities. There is a lack of reliable contemporary malaria maps in endemic countries in sub-Saharan Africa. This problem is particularly acute in low malaria transmission countries such as those located in the horn of Africa. Methods Data from a national malaria cluster sample survey in 2005 and routine cluster surveys in 2007 were assembled for Somalia. Rapid diagnostic tests were used to examine the presence of Plasmodium falciparum parasites in finger-prick blood samples obtained from individuals across all age-groups. Bayesian geostatistical models, with environmental and survey covariates, were used to predict continuous maps of malaria prevalence across Somalia and to define the uncertainty associated with the predictions. Results For analyses the country was divided into north and south. In the north, the month of survey, distance to water, precipitation and temperature had no significant association with P. falciparum prevalence when spatial correlation was taken into account. In contrast, all the covariates, except distance to water, were significantly associated with parasite prevalence in the south. The inclusion of covariates improved model fit for the south but not for the north. Model precision was highest in the south. The majority of the country had a predicted prevalence of Conclusion The maps showed that malaria transmission in Somalia varied from hypo- to meso-endemic. However, even after including the selected covariates in the model, there still remained a considerable amount of unexplained spatial variation in parasite prevalence, indicating effects of other factors not captured in the study. Nonetheless the maps presented here provide the best contemporary information on malaria prevalence in Somalia.

  16. Untreated Isolated Sytolic Hypertension among Middle-Aged and Old Adults in the United States: Trends in the Prevalence by Demographic Factors During 1999–2010

    Directory of Open Access Journals (Sweden)

    Xuefeng Liu

    2015-01-01

    Full Text Available Isolated systolic hypertension (ISH predominates hemodynamic hypertension subtypes and becomes a significant factor for cardiovascular and renal outcomes in middle-aged and old adults. The prevalence and changes of untreated ISH have not been fully investigated in this population. A total of 12,097 participants aged ≥40 years were selected from the National Health and Nutrition Examination Survey 1999–2010. The overall prevalence of untreated ISH was 15.2%. The prevalence decreased significantly from 16.8% in 1999–2004 to 13.5% in 2005–2010. Females, non-Hispanic blacks, and adults with low education had higher prevalence of untreated ISH than males, non-Hispanic whites, and adults with high education, respectively. Compared with 1999–2004, the prevalence of untreated ISH in 2005–2010 reduced in old adults (28.0% versus 37.7%, females (14.3% versus 19.5%, and non-Hispanic whites (12.7% versus 16.2%. The stratified prevalence of untreated ISH decreased in 2005–2010 in non-Hispanic white females (12.8% versus 18.6% and females who did not attend college (16.9% versus 21.8%. Untreated ISH is more prevalent in old and female subjects, and significant improvements in these groups suggest that public health measures or changes are in the right direction.

  17. Bayes linear covariance matrix adjustment

    CERN Document Server

    Wilkinson, Darren J

    1995-01-01

    In this thesis, a Bayes linear methodology for the adjustment of covariance matrices is presented and discussed. A geometric framework for quantifying uncertainties about covariance matrices is set up, and an inner-product for spaces of random matrices is motivated and constructed. The inner-product on this space captures aspects of our beliefs about the relationship between covariance matrices of interest to us, providing a structure rich enough for us to adjust beliefs about unknown matrices in the light of data such as sample covariance matrices, exploiting second-order exchangeability and related specifications to obtain representations allowing analysis. Adjustment is associated with orthogonal projection, and illustrated with examples of adjustments for some common problems. The problem of adjusting the covariance matrices underlying exchangeable random vectors is tackled and discussed. Learning about the covariance matrices associated with multivariate time series dynamic linear models is shown to be a...

  18. Age trends in the prevalence of cervical squamous intraepithelial lesions among HIV-positive women in Cameroon: a cross-sectional study

    LENUS (Irish Health Repository)

    Atashili, Julius

    2012-10-29

    AbstractBackgroundCervical squamous intra-epithelial lesions (SIL) are more frequent in HIV-positive women overall. However the appropriate age at which to begin and end cervical cancer screening for early detection of lesions in HIV-positive women is not clear. We assessed the age-specific prevalence of any SIL and SIL requiring colposcopy in HIV-positive women in Cameroon.MethodsWe enrolled, interviewed and conducted conventional cervical cytology in 282 women, aged 19--68 years, initiating antiretroviral therapy in three clinics in Cameroon. In bivariable analyses, the crude relationship between age and the presence of lesions was assessed using locally weighted regression (LOWESS) methods. In multivariate analyses, generalized linear models with prevalence as the outcome, an identity link and a binomial distribution, were used to estimate prevalence differences. Bias analyses were conducted to assess the potential effect of inaccuracies in cytology.ResultsSIL were detected in 43.5% of the 276 women with satisfactory samples, 17.8% of whom had ASC-H\\/HSIL. On average, women aged 26 to 59 tended to have a slightly higher prevalence of any SIL than other women (Prevalence difference PD: 6.5%; 95%CI: -11.4, 24.4%). This PD was a function of CD4 count (heterogeneity test p-value =0.09): amongst patients with CD4 counts less than 200cells\\/uL, the prevalence was higher in patients aged 26--59, while there was essentially no difference amongst women with CD4 counts greater than 200 cells\\/uL. ASC-H\\/HSIL were present in women as young as 19 and as old as 62. Overall the prevalence of ASC-H\\/HSIL increased by 0.7% (95%CI: -3.8%, 5.1%) per decade increase in age.ConclusionBoth severe and less severe lesions were prevalent at all ages suggesting little utility of age-targeted screening among HIV-positive women. Nevertheless, the long-term evolution of these lesions needs to be assessed in prospective studies.

  19. Prevalence and sport-related predictors of disturbed eating attitudes and behaviors: Moderating effects of sex and age.

    Science.gov (United States)

    Lanfranchi, M-C; Maïano, C; Morin, A J S; Therme, P

    2014-08-01

    Very few studies examined the prevalence and sport-related predictors of disturbed eating attitudes and behaviors (DEABs) among adolescents involved in sport practice, and their results are mixed and inconclusive. These inconsistencies are most likely due to their methodological heterogeneity and to the fact that none of these studies took into consideration the potentially relevant characteristics of the sport practice context. This study attempts to answer this limitation among French adolescents not involved or involved in various sports contexts defined based on their organization, leanness-centration, and competitive level. Participants were 335 adolescents involved in sport practice, and 435 adolescents not involved in any form of regular sport practice. The DEABs were measured using the Eating Attitudes Test-26. Global results do not showed any significant association between the status of the participants and DEAB. However, these results drastically changed when we considered the potential moderating role of sex and age on these relations. Indeed, sports involvement in general, and involvement in leanness and competitive sports were found to exert sex- and age-differentiated effects on the risks of presenting clinically significant levels of DEAB. This study suggests the importance of monitoring, preventive, and early intervention mechanisms within the context of practice, particularly for adolescent girls.

  20. Prevalence of HHV-6 in cerebrospinal fluid of children younger than 2 years of age with febrile convulsion.

    Directory of Open Access Journals (Sweden)

    Setareh Mamishi

    2014-04-01

    Full Text Available Febrile convulsion is a common disorder in children. Viral infections such as human herpes virus 6 (HHV-6 which results in roseola infantum may contribute to developing seizure. The objective of this study was to determine the prevalence of HHV-6 by detecting DNA in cerebrospinal fluid (CSF of children with febrile convulsion and without any rash of roseola infantum.In this descriptive cross-sectional study, CSF of 100 children younger than 2 years of age with febrile convulsion was evaluated for detecting HHV-6 DNA by PCR. All of them were referred to emergency ward in Pediatric Medical Center from March 2010 to March 2011. General information, clinical manifestations, laboratory tests and outcomes were collected in the questionnaires.One hundred children including 59 males and 41 females were evaluated. HHV-6 was detected from CSF in six patients (6% by PCR. Mean age was 8 months old. All children were younger than 12 months old. The most common primary manifestation was fever alone. None of them had rash. Majority of cases occurred in winter. All patients recovered without any encephalitis.These findings showed that primary infection with HHV-6 is frequently associated with febrile convulsion in infants which may be at risk for subsequent development of epilepsy.

  1. Prevalence and sport-related predictors of disturbed eating attitudes and behaviors: Moderating effects of sex and age.

    Science.gov (United States)

    Lanfranchi, M-C; Maïano, C; Morin, A J S; Therme, P

    2014-08-01

    Very few studies examined the prevalence and sport-related predictors of disturbed eating attitudes and behaviors (DEABs) among adolescents involved in sport practice, and their results are mixed and inconclusive. These inconsistencies are most likely due to their methodological heterogeneity and to the fact that none of these studies took into consideration the potentially relevant characteristics of the sport practice context. This study attempts to answer this limitation among French adolescents not involved or involved in various sports contexts defined based on their organization, leanness-centration, and competitive level. Participants were 335 adolescents involved in sport practice, and 435 adolescents not involved in any form of regular sport practice. The DEABs were measured using the Eating Attitudes Test-26. Global results do not showed any significant association between the status of the participants and DEAB. However, these results drastically changed when we considered the potential moderating role of sex and age on these relations. Indeed, sports involvement in general, and involvement in leanness and competitive sports were found to exert sex- and age-differentiated effects on the risks of presenting clinically significant levels of DEAB. This study suggests the importance of monitoring, preventive, and early intervention mechanisms within the context of practice, particularly for adolescent girls. PMID:23336350

  2. Probit Models to Investigate Prevalence of Total Diagnosed and Undiagnosed Diabetes among Aged 45 Years or Older Adults in China

    Science.gov (United States)

    Yin, Minghui; Augustin, Balekouzou; Shu, Chang; Qin, Tingting; Yin, Ping

    2016-01-01

    The aims of this study are to identify the most important predictors of total diagnosed and undiagnosed diabetes and estimate the mean change in the predicted probability among aged 45+ adults in China. We used baseline data collected from 2011 wave of the China Health and Retirement Longitudinal Study (CHARLS) (n = 9,513). First, we estimated the prevalence of diagnosed, measured, total diagnosed, and undiagnosed diabetes. Second, we used probit models to determine whether individual attributes, socioeconomic characteristics and behavioral health factors, including smoking, alcohol consumption, obesity, central obesity, are associated with total diagnosed and undiagnosed diabetes. We also consider other factors, including contact with medical system, hypertension and urban/rural settings. Third, we estimated average marginal effects of variables in probit models. Among Chinese people aged 45+, the prevalence of diagnosed, measured, total diagnosed and undiagnosed diabetes were 5.8% (95%CI, 5.3%-6.3%), 14.7% (95%CI, 14.0%-15.4%), 17.0% (95%CI, 16.3%-17.7%), 11.3% (95%CI, 10.6%-12.0%), respectively. The probability of total diagnosed diabetes is 3.3% (95% CI, 1.2%-5.3%) and 10.2% (95% CI, 7.0%-13.5%) higher for overweight and obesity than normal BMI, 5.0% (95% CI, 3.0%-7.1%) higher for central obesity than normal waist circumference, 5.4% (95% CI, 3.7%-7.0%) higher for hypertensive than normotensive and 1.8% (95% CI, 0.8%- 2.7%) higher in urban areas than in rural areas, respectively. The probability of undiagnosed diabetes is 2.7% (95% CI, 1.2%-4.2%) and 7.2% (95% CI, 4.7%-9.6%) higher for overweight and obesity than normal BMI, 2.6% (95% CI, 0.9%-4.4%) higher for central obesity than normal waist circumference and 2.6% (95% CI, 1.2%-4.0%) higher for hypertensive than normotensive, respectively, and -1.5% (95% CI, -2.5% to -0.5%) lower for individuals who were in contact with the medical system. Greater focus on prevention of diabetes is necessary for obesity

  3. Deriving covariant holographic entanglement

    CERN Document Server

    Dong, Xi; Rangamani, Mukund

    2016-01-01

    We provide a gravitational argument in favour of the covariant holographic entanglement entropy proposal. In general time-dependent states, the proposal asserts that the entanglement entropy of a region in the boundary field theory is given by a quarter of the area of a bulk extremal surface in Planck units. The main element of our discussion is an implementation of an appropriate Schwinger-Keldysh contour to obtain the reduced density matrix (and its powers) of a given region, as is relevant for the replica construction. We map this contour into the bulk gravitational theory, and argue that the saddle point solutions of these replica geometries lead to a consistent prescription for computing the field theory Renyi entropies. In the limiting case where the replica index is taken to unity, a local analysis suffices to show that these saddles lead to the extremal surfaces of interest. We also comment on various properties of holographic entanglement that follow from this construction.

  4. Covariant holographic entanglement negativity

    CERN Document Server

    Chaturvedi, Pankaj; Sengupta, Gautam

    2016-01-01

    We conjecture a holographic prescription for the covariant entanglement negativity of $d$-dimensional conformal field theories dual to non static bulk $AdS_{d+1}$ gravitational configurations in the framework of the $AdS/CFT$ correspondence. Application of our conjecture to a $AdS_3/CFT_2$ scenario involving bulk rotating BTZ black holes exactly reproduces the entanglement negativity of the corresponding $(1+1)$ dimensional conformal field theories and precisely captures the distillable quantum entanglement. Interestingly our conjecture for the scenario involving dual bulk extremal rotating BTZ black holes also accurately leads to the entanglement negativity for the chiral half of the corresponding $(1+1)$ dimensional conformal field theory at zero temperature.

  5. Differences in the prevalence of hypertension by ethnic origin and age at immigration in a cohort of 5,146 Israelis.

    Science.gov (United States)

    Green, M S; Peled, I

    1992-06-01

    Marked ethnic differences in hypertension prevalence have been described in Jewish immigrants to Israel. The extent to which this phenomenon has persisted after a long period of living in the same country, and whether native-born descendants exhibit similar patterns, is not clear. The aim of this study was to determine the prevalence of hypertension in immigrants to Israel and native-born Israelis by region of origin and age at immigration. Complete data were available for 5,146 subjects (3,607 men and 1,539 women) aged 20-64 years who were employed in Israeli industries and were examined during 1985-1987. In both sexes, Jews originating in the West (Europe and the Americas) had higher blood pressures and a significantly higher prevalence of hypertension than those from northern Africa or Asia, particularly in the age group 20-44 years (17% vs. 9% and 8% in men, respectively, and 9% vs. 3% and 5% in women). There was a significant positive association between the prevalence of hypertension and age at immigration (p less than 0.001) in both sexes, and this finding was present in all ethnic groups. In multiple logistic regression analysis, the associations of hypertension with ethnic origin and age at immigration were only partly explained by variations in body mass index, after controlling for other potentially confounding variables. These findings suggest that despite these subjects' having shared a relatively similar physical environment for many years, ethnic differences in the prevalence of hypertension persist. Immigration at an older age was associated with a higher prevalence of hypertension for both subjects originating in industrialized countries and those originating in nonindustrialized countries, suggesting that the process of immigration itself may adversely affect blood pressure. PMID:1378241

  6. Prevalence of potentially inappropriate prescribing and prescribing omissions in older Irish adults: findings from The Irish LongituDinal Study on Ageing study (TILDA)

    OpenAIRE

    Galvin, Rose; Moriarty, Frank; Cousins, Grainne; Cahir, Caitriona; Motterlini, Nicola; Bradley, Marie; Hughes, Carmel M; Bennett, Kathleen; Susan M. Smith; Fahey, Tom; Kenny, Rose-Anne

    2014-01-01

    Purpose We sought to estimate the prevalence of potentially inappropriate prescriptions (PIP) and potential prescribing omissions (PPOs) using a subset of the STOPP/START criteria in a population based sample of Irish adults aged ≥65 years using data from The Irish LongituDinal Study on Ageing (TILDA). Methods A subset of 26 PIP indicators and 10 PPO indicators from the STOPP/START criteria were applied to the TILDA dataset. PIP/PPO prevalence according to individual STOPP/START criteria and ...

  7. The prevalence of using iodine-containing supplements is low among reproductive-age women, NHANES 1999-2006.

    Science.gov (United States)

    Gahche, Jaime J; Bailey, Regan L; Mirel, Lisa B; Dwyer, Johanna T

    2013-06-01

    During pregnancy, the iodine requirement rises to meet demands for neurological development and fetal growth. If these requirements are not met, irreversible pathological cognitive and behavioral changes to the fetus may ensue. This study estimated the prevalence of iodine-containing dietary supplement (DS) use and intakes of iodine from DSs among pregnant women and nonpregnant women of reproductive age (15-39 y) who were interviewed and examined in NHANES 1999-2006 (n = 6404). Although 77.5% of pregnant women reported taking one or more DSs in the past 30 d, only 22.3% consumed an iodine-containing supplement. Most pregnant women reported using one DS and reported taking this product daily. The vast majority of iodine-containing DSs reported by pregnant women claimed an iodine content of 150 μg iodine/serving on the label. Pregnant women using at least one DS containing iodine had a mean daily iodine intake of 122 μg/d from supplements; the median value was 144 μg/d. Median urinary iodine concentrations (UICs) were similar for pregnant and nonpregnant women in the population aged 15-39 y. The median UIC was 148 μg/L for pregnant women and 133 μg/L for nonpregnant women. The WHO has established a cutoff for insufficient iodine intake at iodine for pregnant women. More research is needed on the iodine intakes of pregnant women and women of reproductive age on their total iodine intake from all sources, not just DSs. PMID:23616501

  8. Prevalence of Chronic Suppurative Otitis Media (CSOM and Associated Hearing Impairment Among School-aged Children in Yemen

    Directory of Open Access Journals (Sweden)

    Salem Muftah

    2015-09-01

    Full Text Available Background: Chronic suppurative otitis media (CSOM is one of the leading causes of preventable disabling hearing impairment (DHI in developing countries. Early detection and management complements advances made in other survival programs, improves work capacity, and enhances learning opportunities for school children. We aimed to determine the prevalence of CSOM and associated DHI among school children aged six to 16 years in Socotra Island, Yemen. Methods: We conducted a cross-sectional community-based survey, from 20 April 2011 to 20 June 2011. The study procedures involved completing a questionnaire, an otoscopic ear examination, an audiometric test of hearing, and tuning fork tests for the type of DHI. Results: A total of 686 children were interviewed and examined for CSOM and associated DHI of CSOM cases. The prevalence of CSOM was 7.4%, (95% CI 5.5–9.4. CSOM status was significantly associated with DHI (p=0.001, but no significant associations were found between demographic characteristics and CSOM status. Logistic regression identified four significant independent contributing factors: history of ear discharge in the last 12 months (odds ratio (OR 7.8, 95% CI 3.9–15.6; swimming in local pools (OR 6.0, 95% CI 1.4–25.4; recurrent respiratory tract infection more than three times per year (OR 5.3, 95% CI 2.5–11.0; and overcrowding with more than three families per house (OR 4.4, 95% CI 1.7–11.5. . Conclusion: The burden of CSOM in the children studied indicates a high level of DHI in these communities within Yemen. A history of ear discharge, swimming in local pools, recurrent respiratory infections, and overcrowded housing were the strongest predictors for CSOM. There is a need for better ear care and screening programs for early detection and management of this disease.

  9. Covariates of Craving in Actively Drinking Alcoholics

    OpenAIRE

    Chakravorty, Subhajit; Samuel T Kuna; Zaharakis, Nikola; O’Brien, Charles P.; Kampman, Kyle M.; Oslin, David

    2010-01-01

    The goal of this cross-sectional study was to assess the relationship of alcohol craving with biopsychosocial and addiction factors that are clinically pertinent to alcoholism treatment. Alcohol craving was assessed in 315 treatment-seeking, alcohol dependent subjects using the PACS questionnaire. Standard validated questionnaires were used to evaluate a variety of biological, addiction, psychological, psychiatric, and social factors. Individual covariates of craving included age, race, probl...

  10. Prevalence of passive smoking in the community population aged 15 years and older in China: a systematic review and meta-analysis

    Science.gov (United States)

    Zeng, Jing; Yang, Shanshan; Wu, Lei; Wang, Jianhua; Wang, Yiyan; Liu, Miao; Zhang, Di; Jiang, Bin; He, Yao

    2016-01-01

    Objectives To estimate the prevalence and distribution of passive smoking in the community population aged 15 years and older in China. Design A systematic review and meta-analysis of cross-sectional studies reporting the prevalence of passive smoking in China and a series of subgroup, trend and sensitivity analyses were conducted in this study. Data source The systematic review and meta-analysis, which included 46 studies with 381 580 non-smokers, estimated the prevalence and distribution of passive smoking in China. All studies were published between 1997 and 2015. Results The pooled prevalence of passive smoking was 48.7% (95% CI 44.8% to 52.5%) and was relatively stable from 1995 to 2013. The prevalence in the subgroups of gender, area, age and time varied from 35.1% (95% CI 31.8% to 38.3%) in the elderly (≥60 years) to 48.6% (95% CI 42.9% to 54.2%) in urban areas. The prevalence was lower in the elderly (≥60 years) than in those between 15 and 59 years of age (OR 1.61, 95% CI 1.44 to 1.81). The difference between females and males in urban and rural areas was not statistically significant (OR: 1.27, 95% CI 0.93 to 1.74 and OR: 1.14, 95% CI 0.82 to 1.58, respectively). In addition, a significantly increasing trend was found among males from 2002 to 2010. Heterogeneity was high in all pooled estimates (I2>98%, p<0.001). Conclusions The high and stable prevalence of passive smoking in China is raising increasing national concern regarding specific research and tobacco control programmes. Attention should be focused on young, middle-aged and male non-smokers regardless of region. PMID:27059465

  11. Secular trends in prevalence of overweight and obesity from 2006 to 2009 in urban asian Indian adolescents aged 14-17 years.

    Directory of Open Access Journals (Sweden)

    Deepak Kumar Gupta

    Full Text Available The present study examines the secular trends in prevalence of overweight and obesity among urban Asian Indian adolescents in New Delhi (North India. The data were derived from cross-sectional sampling of children, 3493 in year 2006 and 4908 in year 2009, aged 14-17 years studying in privately-funded and government-funded schools. Age, gender and Asian Indian-specific cut offs of body mass index (BMI were used to define overweight and obesity. The prevalence of obesity increased significantly from 9.8% in 2006 to 11.7% in 2009 (p<0.01, whereas underweight decreased from 11.3% to 3.9% (p<0.001. There was a significantly higher risk of being overweight (OR 1.28; 95% CI, 1.15-1.42 and obese (OR 1.44; 95% CI, 1.24-1.66 in year 2009 than 2006, after adjusting for age, gender and type of school. Males and privately-funded school children had significantly higher increase in prevalence and risk of being overweight and obese over the three years. In conclusion, this study showed an increasing trend in prevalence of overweight and obesity in urban Asian Indian adolescents. More specifically, the study showed the association of this increasing trend of overweight and obesity prevalence with male gender and high socio-economic status, calling for an urgent need for immediate and targeted preventive measures.

  12. Prevalence of anterior dental trauma and its associated factors among children aged 3-5 years in Jaipur City, India – A cross sectional study

    Science.gov (United States)

    Chalissery, Vemina P.; Marwah, Nikhil; Jafer, Mohammed; Chalisserry, Elna P.; Bhatt, Tanmay; Anil, Sukumaran

    2016-01-01

    Objective: To study the prevalence of anterior dental trauma and its associated factors among 800 preschool children aged 3 to 5 years in Jaipur City, Rajasthan, India. Materials and Methods: A cross-sectional survey was conducted among children aged 3-5 years, who were enrolled in various private and public schools in Jaipur. Parents were asked to fill a form addressing socio-demographic data and clinical examinations were performed by a single dentist. Traumatic dental injuries (TDI) were assessed and recorded based on Andreasen's classification. Associated factors such as sex, socioeconomic status (SES), and the type of injury were also analyzed. The data were analyzed statistically using Statistical Package for the Social Sciences software (version 20). Results: An overall 10.2% prevalence of TDI was observed among the study population. TDI were reported to be more among male children (11.87%) compared to female children (8.14%). Enamel fractures (69%) were the most prevalent type of anterior dental trauma. Upper central incisors were the most frequently affected. The SES of the parents had little influence on the prevalence of TDI. Conclusions: The prevalence rate of dental trauma among children aged 3-5 years was 10.2%. Associated factors, such as SES, were observed to be not significantly correlated to dental trauma among the studied preschoolers. PMID:27195225

  13. Prevalence and socio-economic distribution of hazardous patterns of alcohol drinking: study of alcohol consumption in men aged 25–54 years in Izhevsk, Russia

    OpenAIRE

    Tomkins, S.; Saburova, L.; Kiryanov, N; Andreev, E.; McKee, M; Shkolnikov, V; Leon, D. A.

    2007-01-01

    Aim To estimate the prevalence of hazardous drinking and its socio-economic distribution among Russian men. Design Participants were an age-stratified, population-based random sample of men aged 25–54 years living in Izhevsk, a city in the Urals, Russia. Interviewers administered questionnaires to cohabiting proxy respondents about behavioural indicators of hazardous drinking derived from frequency of hangover, frequency of drinking beverage spirits, episodes in the last year of extended peri...

  14. A comparison of the prevalence of the metabolic syndrome in the United States (US) and Korea in young adults aged 20 to 39 years

    Science.gov (United States)

    This study estimated and compared the prevalence of the Metabolic Syndrome and its individual components in young adults (ages 20-39 years) in the US and Korea using 2003-2004 US and 2005 Korean National Health and Nutrition Examination Survey data. The mean body mass index and rate of metabolic abn...

  15. Evaluation and processing of covariance data

    International Nuclear Information System (INIS)

    These proceedings of a specialists'meeting on evaluation and processing of covariance data is divided into 4 parts bearing on: part 1- Needs for evaluated covariance data (2 Papers), part 2- generation of covariance data (15 Papers), part 3- Processing of covariance files (2 Papers), part 4-Experience in the use of evaluated covariance data (2 Papers)

  16. The prevalence of hypertension, obesity and dyslipidemia in individuals of over 30 years of age belonging to minorities from the pasture area of Xinjiang

    Directory of Open Access Journals (Sweden)

    Luo Wen-Li

    2010-02-01

    Full Text Available Abstract Background The prevalence of population-wide hypertension, obesity and dyslipidemia has not been well studied in the pasture area of Xinjiang. The present epidemiological study was performed to determine the prevalence of hypertension, obesity and dyslipidemia in minority populations from the pasture area of Xinjiang and to discuss the potential risk factors for hypertension. Methods A population-based, cross-sectional study in the Xinjiang pasture area was performed which included 2251 participants aged over 30 years (90.33% participation rate of whom 71.26% were Kazaks. Several risk factors were considered: hypertension (defined as systolic or diastolic blood pressure or both of at least 140/90 mmHg measured on one occasion or treatment for hypertension overweight/obesity (body mass index ≥ 25 kg/m2 alcohol intake, smoking/tobacco use and dyslipidemia. Outcomes were prevalence of hypertension, obesity and dyslipidemia and the associated risk factors of hypertension detected by multivariate logistic regression analysis taking into account various metabolic and lifestyle characteristics. Results The prevalence of hypertension, overweight/obesity and dyslipidemia in all participants from the pasture area of Xinjiang was 51.9%, 47.9% and 49.2% respectively. Independently, the prevalence and awareness of hypertension was 52.6% and 15.3% among Kazaks (n = 1604, 54.6% and 14.1% among Uygurs (n = 418, 39.5% and 16.1% among Mongolians (n = 81 and 43.9% and 18.2% among non-Xinjiang-born Han immigrants (n = 148. The prevalence of overweight/obesity in Kazaks, Uygurs, Mongolians and Han immigrants was 46.7%, 48.9%, 62.5% and 50.3%, respectively. The prevalence of dyslipidemia in the four ethnic groups mentioned was 53.5%, 34.8%, 49.3% and 47.3%, respectively. The mean blood pressure in all participants was 136/86 mmHg (pre-hypertensive, the mean BMI was 24.7 kg/m2. Based on multiple logistic regression analysis, the significant risk factors for

  17. Caries prevalence and risk factors among children aged 0 to 36 months Prevalência de cárie e fatores de risco em crianças de 0 a 36 meses

    OpenAIRE

    Ana Paula Pires dos Santos; Vera Mendes Soviero

    2002-01-01

    The aim of this study was to assess the prevalence of caries and risk factors in outpatients of the Pediatric Ambulatory of the Pedro Ernesto University Hospital aging up to 36 months. After signing informed consent forms, the parents answered a structured questionnaire in order to evaluate risk factors for dental caries, including socioeconomic status, oral hygiene and dietary habits. A single investigator carried out the dental examination which assessed the presence of caries, biofilm and ...

  18. The incredible shrinking covariance estimator

    Science.gov (United States)

    Theiler, James

    2012-05-01

    Covariance estimation is a key step in many target detection algorithms. To distinguish target from background requires that the background be well-characterized. This applies to targets ranging from the precisely known chemical signatures of gaseous plumes to the wholly unspecified signals that are sought by anomaly detectors. When the background is modelled by a (global or local) Gaussian or other elliptically contoured distribution (such as Laplacian or multivariate-t), a covariance matrix must be estimated. The standard sample covariance overfits the data, and when the training sample size is small, the target detection performance suffers. Shrinkage addresses the problem of overfitting that inevitably arises when a high-dimensional model is fit from a small dataset. In place of the (overfit) sample covariance matrix, a linear combination of that covariance with a fixed matrix is employed. The fixed matrix might be the identity, the diagonal elements of the sample covariance, or some other underfit estimator. The idea is that the combination of an overfit with an underfit estimator can lead to a well-fit estimator. The coefficient that does this combining, called the shrinkage parameter, is generally estimated by some kind of cross-validation approach, but direct cross-validation can be computationally expensive. This paper extends an approach suggested by Hoffbeck and Landgrebe, and presents efficient approximations of the leave-one-out cross-validation (LOOC) estimate of the shrinkage parameter used in estimating the covariance matrix from a limited sample of data.

  19. Obesity in preschool children is more prevalent and identified at a younger age when WHO growth charts are used compared with CDC charts.

    Science.gov (United States)

    Maalouf-Manasseh, Zeina; Metallinos-Katsaras, Elizabeth; Dewey, Kathryn G

    2011-06-01

    Our objective was to compare the prevalence and determinants of child obesity using the WHO child growth standards compared with the CDC growth reference. We used data from 143,787 2- to 5-y olds who participated in the Massachusetts Special Supplemental Food and Nutrition Program for Women, Infants and Children (WIC) program between 2001 and 2006. The prevalence of obesity (>95th percentile, BMI-for-age) was 23.3% when we used the WHO standards vs. 16.9% using the CDC reference; for obesity plus overweight (>85th percentile), the prevalence was 42.2 vs. 33.8%, respectively. The difference between the prevalence estimates was greatest at 24-36 mo of age. Multivariate logistic regression analysis indicated that child obesity (based on the WHO standards) was more common in boys, Hispanics, children of less educated mothers, and those born to obese mothers. These results confirm that the prevalence of child obesity is higher according to the WHO standards and indicate that the WHO charts allow for a more timely detection of obesity in childhood.

  20. A Radiographic Study on the Associations of Age and Prevalence of Vertebral Fractures with Abdominal Aortic Calcification in Japanese Postmenopausal Women and Men

    Directory of Open Access Journals (Sweden)

    Jun Iwamoto

    2010-01-01

    Full Text Available The purpose of the present study was to determine the associations of age and history of non- and low-traumatic fractures with the severity of abdominal aortic calcification in Japanese postmenopausal women and men. Four hundred and one Japanese persons (24 men and 377 postmenopausal women, mean age: 73.8 years for whom thoracic and lumbar spine radiographs had been obtained to evaluate their posture prior to patient participation in a fall-prevention exercise program were enrolled. The associations of sex, age, history of hip fracture, prevalence of vertebral fracture, and spondylosis grade (the Nathan degree with the severity of abdominal aortic calcification (length of calcification, as evaluated according to the number of vertebral bodies were analyzed. Nine subjects (2.2% had a history of hip fracture, and 221 (55.1% had at least one prevalent vertebral fracture. Two hundred and sixty-seven subjects (66.6% had first-degree spondylosis. Age and the number of prevalent vertebral fractures, but not sex, history of hip fracture, or spondylosis grade, were significantly associated with the severity of abdominal aortic calcification. The present study confirmed that age and the number of vertebral fractures were associated with the severity of abdominal aortic calcification in Japanese postmenopausal women and men.

  1. Age- and Gender-Specific Prevalence of Cardiovascular Risk Factors in 40 102 Patients With First-Ever Ischemic Stroke A Nationwide Danish Study

    DEFF Research Database (Denmark)

    Andersen, Klaus Kaae; Andersen, Z. J.; Olsen, T. S.

    2010-01-01

    Background and Purpose—We describe the prevalence of cardiovascular risk factors at stroke onset in men and women of all ages. Methods—A registry started in 2001, designed to register all hospitalized stroke patients in Denmark, now holds 40 102 patients with first-ever ischemic stroke. Patients ...... heart disease, and, in men, also atrial fibrillation go down after the age of 70 to 80 years.......Background and Purpose—We describe the prevalence of cardiovascular risk factors at stroke onset in men and women of all ages. Methods—A registry started in 2001, designed to register all hospitalized stroke patients in Denmark, now holds 40 102 patients with first-ever ischemic stroke. Patients...... underwent evaluation including stroke severity (Scandinavian Stroke Scale), CT, and cardiovascular risk factors: hypertension, atrial fibrillation, diabetes mellitus, intermittent arterial claudication, previous myocardial infarction, body mass index, smoking, and alcohol consumption. We estimated...

  2. Diarrhoea prevalence in children under five years of age in rural Burundi: an assessment of social and behavioural factors at the household level

    Directory of Open Access Journals (Sweden)

    Katharina Diouf

    2014-08-01

    Full Text Available Background: Diarrhoea is the second leading cause of child mortality worldwide. Low- and middle-income countries are particularly burdened with this both preventable and treatable condition. Targeted interventions include the provision of safe water, the use of sanitation facilities and hygiene education, but are implemented with varying local success. Objective: To determine the prevalence of and factors associated with diarrhoea in children under five years of age in rural Burundi. Design: A cross-sectional survey was conducted among 551 rural households in northwestern Burundi. Areas of inquiry included 1 socio-demographic information, 2 diarrhoea period prevalence and treatment, 3 behaviour and knowledge, 4 socio-economic indicators, 5 access to water and water chain as well as 6 sanitation and personal/children's hygiene. Results: A total of 903 children were enrolled. The overall diarrhoea prevalence was 32.6%. Forty-six per cent (n=255 of households collected drinking water from improved water sources and only 3% (n=17 had access to improved sanitation. We found a lower prevalence of diarrhoea in children whose primary caretakers received hygiene education (17.9%, boiled water prior to its utilisation (19.4% and were aged 40 or older (17.9%. Diarrhoea was associated with factors such as the mother's age being less than 25 and the conviction that diarrhoea could not be prevented. No gender differences were detected regarding diarrhoea prevalence or the caretaker's decision to treat. Conclusions: Diarrhoea prevalence can be reduced through hygiene education and point-of use household water treatment such as boiling. In order to maximise the impact on children's health in the given rural setting, future interventions must assure systematic and regular hygiene education at the household and community level.

  3. Prevalência e severidade da cárie dentária em escolares de seis e doze anos de idade Prevalence and severity of dental caries among schoolchildren aged six and twelve

    Directory of Open Access Journals (Sweden)

    Jefferson Luiz Traebert

    2001-06-01

    Full Text Available OBJETIVO: Investigar a prevalência e a severidade da cárie dentária e as necessidades de tratamento em escolares de 6 e 12 anos de idade, comparando-se os alunos de escolas públicas com os de privadas. MÉTODOS: Foi estudada a população de escolares do município de Blumenau, SC, a partir de uma amostra de 1.473 escolares, representativa de quatro estratos: escolares de 6 anos de escolas públicas, de 6 anos de escolas privadas, de 12 anos de escolas públicas e de 12 anos de escolas privadas. Utilizaram-se os critérios de diagnóstico da Organização Mundial de Saúde (1997. RESULTADOS: A prevalência de cárie na dentição decídua em escolares de 6 anos foi de 60,9% em escolas públicas e de 34,9% em escolas privadas (pOBJECTIVE: To determine the prevalence and severity of dental caries and to assess treatment needs among schoolchildren aged 6 and 12 in Blumenau, Brazil, and to compare the results found for private and public schools. METHODS: A schoolchildren population of Blumenau, SC, Brazil, was studied. A random sample of 1,473 schoolchildren from Blumenau, Brazil, was obtained. Four strata were studied: 6 and 12 years old schoolchildren attending public and private schools. WHO (1997 criteria for caries diagnosis and treatment needs were used. RESULTS: The prevalence of caries in the primary dentition of 6-years-old children was 60.9% and 34.9% in public and private schools (p<0.0001, respectively. The mean DMF-T for children aged 6 was 2.98 and 1.32 for public and private schools, respectively, (p<0.0001, and 2.42 for the whole sample. The prevalence of caries in the permanent dentition of 12-years-old children was 54.7% and the mean DMF-T was 1.46 for public schools. The response rate for private schools was low and the results could not be analyzed. Forty-two percent and 77.0% of children aged six of public and private schools, respectively, had no treatment needs. For those aged 12, the percentage was 53.0% for public

  4. General covariance in computational electrodynamics

    DEFF Research Database (Denmark)

    Shyroki, Dzmitry; Lægsgaard, Jesper; Bang, Ole;

    2007-01-01

    We advocate the generally covariant formulation of Maxwell equations as underpinning some recent advances in computational electrodynamics—in the dimensionality reduction for separable structures; in mesh truncation for finite-difference computations; and in adaptive coordinate mapping as opposed...

  5. The coexistence of asthma and chronic obstructive pulmonary disease (COPD: prevalence and risk factors in young, middle-aged and elderly people from the general population.

    Directory of Open Access Journals (Sweden)

    Roberto de Marco

    Full Text Available BACKGROUND: The joint distribution of asthma and chronic obstructive pulmonary disease (COPD has not been well described. This study aims at determining the prevalence of self-reported physician diagnoses of asthma, COPD and of the asthma-COPD overlap syndrome and to assess whether these conditions share a common set of risk factors. METHODS: A screening questionnaire on respiratory symptoms, diagnoses and risk factors was administered by mail or phone to random samples of the general Italian population aged 20-44 (n = 5163 45-64 (n = 2167 and 65-84 (n = 1030 in the frame of the multicentre Gene Environment Interactions in Respiratory Diseases (GEIRD study. RESULTS: A physician diagnosis of asthma or COPD (emphysema/chronic bronchitis/COPD was reported by 13% and 21% of subjects aged <65 and 65-84 years respectively. Aging was associated with a marked decrease in the prevalence of diagnosed asthma (from 8.2% to 1.6% and with a marked increase in the prevalence of diagnosed COPD (from 3.3% to 13.3%. The prevalence of the overlap of asthma and COPD was 1.6% (1.3%-2.0%, 2.1% (1.5%-2.8% and 4.5% (3.2%-5.9% in the 20-44, 45-64 and 65-84 age groups. Subjects with both asthma and COPD diagnoses were more likely to have respiratory symptoms, physical impairment, and to report hospital admissions compared to asthma or COPD alone (p<0.01. Age, sex, education and smoking showed different and sometimes opposite associations with the three conditions. CONCLUSION: Asthma and COPD are common in the general population, and they coexist in a substantial proportion of subjects. The asthma-COPD overlap syndrome represents an important clinical phenotype that deserves more medical attention and further research.

  6. Prevalence and determinants of co-use of alcohol and tobacco among men in working age group (18-59 years in India

    Directory of Open Access Journals (Sweden)

    Ankit Anand

    2016-03-01

    Full Text Available Background: The relationship between tobacco and alcohol use is very important in making strategies containing use of these products. Alcohol and tobacco use were studied separately in Indian studies, which can undermine their co-occurrences. The objective of the study is to know the prevalence and socio-economic determinants of co-occurrence of alcohol and tobacco use among men in working age groups.Data Sources: The data from the Study on Global Ageing and Adult Health (SAGE Wave1 was used. It was a cross sectional household survey, which collected information for adults aged 18 years and above.Results: The prevalence of co-use of tobacco and alcohol among men aged 18-59 years was 23.5%. High use of tobacco was found among alcohol user. Age cohorts were also the important determinants of alcohol and tobacco use. The inverted U or V-shape relation was found between age groups and co-use of tobacco and alcohol. The prevalence was lowest for age groups 18-24 years and 50-59 years. Low education attainment and working in informal sector were the main risk factors for high co-use of these substances among men. The study also tried to look at the relationship between the co-use of alcohol and tobacco with some selected health indicators. Use of alcohol and tobacco was significantly related with under nutrition and increasing blood pressure levels among men in India.Conclusion: To contain the use of alcohol and tobacco to improve heath condition among adult men, policies and strategies must be form keeping the importance of their co-occurrences.

  7. A community-based iron supplementation program, "Iron-Like Turkey", and the following prevalence of anemia among infants aged 12-23 months.

    Science.gov (United States)

    Yalçın, S Songül; Tezel, Başak; Yurdakök, Kadriye; Pekcan, Gülden; Ozbaş, Sema; Köksal, Eda; Tunç, Bahattin; Sahinli, Selvi; Altunsu, A Tanju; Köse, M Rifat; Buzgan, Turan; Akdağ, Recep

    2013-01-01

    During the second year of the "Iron-like Turkey" Project, in which all children aged 4-6 months in Turkey receive iron supplementation for 5 months, we aimed to assess the utilization of iron supplementation in the field, as well as the prevalence of anemia in healthy infants aged 12-23 months, while determining a variety of sociodemographic and nutritional factors for anemia in three of the 12 NUTS (Nomenclature of Territorial Units for Statistics) regions (regions with the highest, lowest and middle under-5 malnutrition levels). In a community-based, cross-sectional survey using a multi-staged, weighted, cluster-selected sample, children aged 12-23 months with birthweight ≥2500 g, no chronic illness, no history of blood disease, and from term and singleton pregnancy were enrolled; 1589 children met the criteria. The mean±SD age of children surveyed was 17.8±3.6 months. Of the parents, 72.4% claimed that their physician had recommended iron supplementation, and 68.8% had given supplementation to their children. Overall prevalence of anemia was 7.3%. Multivariate analysis revealed that the frequency of anemia decreased significantly in older infants, when supplementation was recommended by health providers, when an infant was breastfed longer than 6 months, and when the mother received iron supplementation during pregnancy. However, anemia prevalence increased when the infant received iron supplementation at a later age (³9 months), lived in a crowded family (³6 persons), and when the mother had a history of iron deficiency anemia. Anemic infants had significantly lower z scores of weight for age than non-anemic ones. This survey suggests that iron supplementation during pregnancy, initiation of iron supplementation in infants at 4-6 months of age, effective counseling on supplementation, subsequent compliance, support of breastfeeding, and effective training of health care personnel are effective strategies for prevention of anemia in the community.

  8. Prevalence, intensity of infection and risk factors of urinary schistosomiasis in pre-school and school aged children in Guma Local Government Area, Nigeria

    Institute of Scientific and Technical Information of China (English)

    EU Amuta; RS Houmsou

    2014-01-01

    Objective: To determine the prevalence and intensity of infection and the risk factors associated with urinary schistosomiasis in pre-school and school aged children in Guma Local Government Area of Benue State, Nigeria. Methods: Urine filtration technique using polycarbonate membrane filters was employed to process urine specimens and to determine presence of Schistosoma haematobium eggs in urine. Questionnaires were also administered to children to collect information on socio-demographic data and water-contact activities. Results: An overall prevalence of 55.0% (165/300) was recorded out of the 300 urine samples examined. Prevalence of infection varied between 36.0%-64.0% with a significant difference (χ2= 11.59, P=0.041) between the different communities visited. Males were more infected (60.6%, 103/170) than females (47.7%, 62/130) with a significant difference (χ2= 4.95, P=0.026). The age-related prevalence showed higher prevalence (70.5%, 36/52) in the 11-15 year old children than that in the 1-5 year old ones (44.9%, 53/118). A significant difference was observed in the prevalence between the age groups (χ2=10.56, P=0.014). The prevalence of light intensity of infection (1-49 eggs/10 mL of urine) (86.6%) was significantly higher than that of heavy intensity of infection (≥50 eggs/10 mL of urine) (13.3%) in the area (t=16.48, P=0.000). Water contact activities of the children revealed that children that were involved in irrigation and those that went swimming in water bodies were observed to be at higher risk of becoming infected with urinary schistosomiasis in the area with odd ratios (risk factors) of 2.756 (1.334-5.693) and 2.366 (1.131-4.948) respectively at P<0.05 level. Conclusions: The study revealed the hyperendemicity of urinary schistosomiasis in the pre-school and school aged children in Guma Local Government Area. It is therefore recommended that praziquantel should be administered to children in the area and systematic epidemiological

  9. Prevalence of metabolic syndrome in a cohort of systemic lupus erythematosus patients from Northeastern Brazil: association with disease activity, nephritis, smoking, and age.

    Science.gov (United States)

    Medeiros, Marta Maria das Chagas; Xavier de Oliveira, Ídila Mont'Alverne; Ribeiro, Ádilla Thaysa Mendes

    2016-01-01

    Systemic lupus erythematosus (SLE), an autoimmune inflammatory disease, is associated with an increased prevalence of accelerated atherosclerosis and cardiovascular events. Metabolic syndrome (MetS) is a set of cardiovascular risk factors in SLE patients, which may lead to a proinflammatory condition and increased morbidity and mortality. The objective of this study was to evaluate the prevalence of MetS in a cohort of SLE patients versus healthy controls, and to analyze the association of clinical and demographic factors. SLE patients (n = 146) treated at a Northeast Brazilian university hospital were evaluated with regard to demographic, clinical, laboratory, and anthropometric parameters and compared to controls (n = 101). MetS was diagnosed according to the definition of 2005 NCEP/ATP III. The average age of SLE patients was 41.7 ± 12.5 years, and 91.8 % were female. MetS was significantly more prevalent in SLE patients (45.2 %) than in controls (32.7 %; p = 0.04). The MetS components such as hypertension, diabetes, and hypertriglyceridemia were significantly more prevalent in SLE. In the univariate analysis, MetS in SLE patients was associated with age, disease duration, Systemic Lupus International Collaborating Clinics/American College of Rheumatology damage index, smoking, menopause, nephritis, cyclophosphamide use, prednisone dose, and chloroquine use, which appeared to have a protective effect. In the logistic regression analysis, age, disease activity, nephritis, and smoking were statistically significant. The prevalence of MetS observed in our cohort of SLE patients from Northeastern Brazil is higher than controls. MetS components should be routinely investigated to minimize the occurrence of MetS and associated cardiovascular morbidity and mortality. PMID:26149124

  10. Prevalence and Health Outcomes of Functional Gastrointestinal Symptoms in Infants From Birth to 12 Months of Age

    OpenAIRE

    Vandenplas, Yvan; Abkari, Abdelhak; Bellaiche, Marc; Benninga, Marc; Chouraqui, Jean Pierre; ÇokuÐraþ, FügenÇullu; Harb, Tracy; Hegar, Badriul; Lifschitz, Carlos; Ludwig, Thomas; Miqdady, Mohamed; de Morais, Mauro Batista; Osatakul, Seksit; Salvatore, Silvia; Shamir, Raanan

    2015-01-01

    ABSTRACT Objectives: The aim of the study was to review published evidence and the opinion of practising clinicians on the prevalence and long-term health consequences of functional gastrointestinal symptoms in infants younger than 12 months. Methods: PubMed was searched from inception to November 2014 to find articles reporting the prevalence and long-term health outcomes of infantile colic, regurgitation, functional constipation, functional diarrhoea, and dyschezia in infants younger than

  11. Divorce and changes in the prevalence of psychotropic medication use: a register-based longitudinal study among middle-aged Finns.

    Science.gov (United States)

    Metsä-Simola, Niina; Martikainen, Pekka

    2013-10-01

    The annual prevalence of psychotropic medication use exceeds 10 percent in Europe and the United States, the prevalence being higher among the divorced than the married. We analysed changes in the three-month prevalence of psychotropic medication use (psycholeptics and psychoanaleptics excluding medication for dementia) by proximity to divorce, sex, medication type and socio-demographic characteristics, using register-data on 304,111 Finns between 25 and 64 years of age, of whom 23,956 divorced between 1995 and 2003 and 142,093 were continuously married from 1995 to 2004. Five years before divorce, men and women already displayed about one percentage point higher prevalence of psychotropic medication use than those who continued their marriage. The excess prevalence increased with approaching divorce and peaked six to nine months before divorce, reaching 7.3 percent (95% CI 6.8-8.0) among divorcing men and 8.1 percent (95% CI 7.5-8.8) among divorcing women. The peak was followed by an 18-month decline, after which the excess compared to the continuously married settled at nearly three percentage points. The excess was not due to being socio-economically disadvantaged, and socio-demographic factors also seemed to have few modifying effects. The changes in prevalence were largest for antidepressants and almost non-existent for antipsychotics. Our results suggest that the high prevalence of psychotropic medication use among the divorced results both from selective factors already present five years before divorce and the acute and long-term causal effects of becoming and being divorced. Counselling is needed for individuals in the process of divorce, rather than economic support for divorced individuals.

  12. Impact of Age, Season, and Flowing vs. Stagnant Water Habitat on Avian Influenza Prevalence in Mute Swan (Cygnus olor) in Belgium.

    Science.gov (United States)

    Lambrecht, B; Marché, S; Houdart, P; van den Berg, T; Vangeluwe, D

    2016-05-01

    Due to their probable role in the spread of Asian highly pathogenic avian influenza (HPAI) H5N1 virus, and in order to explore its implication in the low pathogenic avian influenza (LPAI) virus epidemiology, mute swans represent one particular wild bird species specifically targeted in the avian influenza (AI) surveillance elaborated in Belgium. A total of 640 individual mute swans have been sampled during a 4-yr AI surveillance program (2007-2010) to determine the AI seroprevalence and viroprevalence in this species; all were analyzed through age, temporal, and habitat (flowing and stagnant water) factors. Using a nucleoprotein (NP)-based ELISA, a global antibody prevalence of 35% has been found and was characterized by two peaks in the winter and the summer that might be indicative of a greater LPAI virus circulation in the autumn than in the spring. A significantly higher antibody prevalence was detected in adult swans (53.8%) as compared to juveniles (15.5%). In contrast, a low prevalence of infection (2.7%) was found, mainly in juvenile mute swans and only during the autumn migration period. Interestingly, an impact of water habitat was observed based on the comparison of the antibody prevalence and prevalence of infection from swan populations living on stagnant water vs. flowing water, suggesting that stagnant water provides a more-favorable environment for LPAI persistence and transmission. PMID:27309074

  13. Shrinkage estimators for covariance matrices.

    Science.gov (United States)

    Daniels, M J; Kass, R E

    2001-12-01

    Estimation of covariance matrices in small samples has been studied by many authors. Standard estimators, like the unstructured maximum likelihood estimator (ML) or restricted maximum likelihood (REML) estimator, can be very unstable with the smallest estimated eigenvalues being too small and the largest too big. A standard approach to more stably estimating the matrix in small samples is to compute the ML or REML estimator under some simple structure that involves estimation of fewer parameters, such as compound symmetry or independence. However, these estimators will not be consistent unless the hypothesized structure is correct. If interest focuses on estimation of regression coefficients with correlated (or longitudinal) data, a sandwich estimator of the covariance matrix may be used to provide standard errors for the estimated coefficients that are robust in the sense that they remain consistent under misspecification of the covariance structure. With large matrices, however, the inefficiency of the sandwich estimator becomes worrisome. We consider here two general shrinkage approaches to estimating the covariance matrix and regression coefficients. The first involves shrinking the eigenvalues of the unstructured ML or REML estimator. The second involves shrinking an unstructured estimator toward a structured estimator. For both cases, the data determine the amount of shrinkage. These estimators are consistent and give consistent and asymptotically efficient estimates for regression coefficients. Simulations show the improved operating characteristics of the shrinkage estimators of the covariance matrix and the regression coefficients in finite samples. The final estimator chosen includes a combination of both shrinkage approaches, i.e., shrinking the eigenvalues and then shrinking toward structure. We illustrate our approach on a sleep EEG study that requires estimation of a 24 x 24 covariance matrix and for which inferences on mean parameters critically

  14. Data Covariances from R-Matrix Analyses of Light Nuclei

    Energy Technology Data Exchange (ETDEWEB)

    Hale, G.M., E-mail: ghale@lanl.gov; Paris, M.W.

    2015-01-15

    After first reviewing the parametric description of light-element reactions in multichannel systems using R-matrix theory and features of the general LANL R-matrix analysis code EDA, we describe how its chi-square minimization procedure gives parameter covariances. This information is used, together with analytically calculated sensitivity derivatives, to obtain cross section covariances for all reactions included in the analysis by first-order error propagation. Examples are given of the covariances obtained for systems with few resonances ({sup 5}He) and with many resonances ({sup 13}C ). We discuss the prevalent problem of this method leading to cross section uncertainty estimates that are unreasonably small for large data sets. The answer to this problem appears to be using parameter confidence intervals in place of standard errors.

  15. Diarrhoea prevalence in children under five years of age in rural Burundi: an assessment of social and behavioural factors at the household level

    OpenAIRE

    Diouf, Katharina; Tabatabai, Patrik; Rudolph, Jochen; Marx, Michael

    2014-01-01

    Background: Diarrhoea is the second leading cause of child mortality worldwide. Low- and middle-income countries are particularly burdened with this both preventable and treatable condition. Targeted interventions include the provision of safe water, the use of sanitation facilities and hygiene education, but are implemented with varying local success.Objective: To determine the prevalence of and factors associated with diarrhoea in children under five years of age in rural Burundi.Design: A ...

  16. Prevalence of Self-Reported Pain, Joint Complaints and Knee or Hip Complaints in Adults Aged ≥ 40 Years: A Cross-Sectional Survey in Herne, Germany

    OpenAIRE

    Ulrich Thiem; Rainer Lamsfuß; Sven Günther; Jochen Schumacher; Christian Bäker; Endres, Heinz G.; Josef Zacher; Burmester, Gerd R.; Ludger Pientka

    2013-01-01

    BACKGROUND: Pain and musculoskeletal complaints are among the most common symptoms in the general population. Despite their epidemiological, clinical and health economic importance, prevalence data on pain and musculoskeletal complaints for Germany are scarce. METHODS: A cross-sectional survey of a random sample of citizens of Herne, Germany, aged ≥ 40 years was performed. A detailed self-complete postal questionnaire was used, followed by a short reminder questionnaire and telephone contacts...

  17. Prevalence of Wuchereria Bancrofti Antigenemia and Associated Factors Among Children of School Age Born After Initiation of Mass Drug Administration with ivermectin and albendazole in Rufiji district, Tanzania

    OpenAIRE

    Clarer, Jones

    2012-01-01

    The National Lymphatic Filariasis (LF) Elimination Programme use Ivermectin and Albendazole mass drug administration (MDA) for the control of LF. Screening children of school age has successfully been used for mapping geographical distribution of LF worldwide. The implementation of MDA for LF in Rufiji district started in 2002 and up to 2011, nine rounds had been administered. The prevalence of LF after MDA was not known, thus this study aimed to screen children born during the period of prog...

  18. Obesity increases the prevalence and severity of focal knee abnormalities diagnosed using 3T MRI in middle-aged subjects - data from the osteoarthritis initiative

    Energy Technology Data Exchange (ETDEWEB)

    Laberge, Marc A.; Baum, Thomas; Virayavanich, Warapat; Nardo, Lorenzo; Link, Thomas M. [University of California San Francisco, Musculoskeletal and Quantitative Imaging Research, Department of Radiology and Biomedical Imaging, San Francisco, CA (United States); Nevitt, M.C.; Lynch, J.; McCulloch, C.E. [University of California San Francisco, Department of Epidemiology and Biostatistics, San Francisco, CA (United States)

    2012-06-15

    To study the effect of BMI on the prevalence, severity, and 36-month progression of early degenerative changes in the knee by using 3T MRI in middle-aged subjects without radiographic osteoarthritis (OA). We examined baseline and 36-month follow-up MR studies from 137 middle-aged individuals (45-55 years old) with risk factors for knee OA but no radiographic OA from the Osteoarthritis Initiative. Subjects were grouped into three categories: normal BMI (BMI < 25 kg/m{sup 2}, n = 38), overweight (BMI 25-29.9 kg/m{sup 2}, n = 37), and obese (BMI {>=} 30 kg/m{sup 2}, n = 62). Using 3T MRI, cartilage, meniscus, and bone marrow abnormalities were graded using the OA Whole-organ MR Imaging Score (WORMS). The statistical analysis was corrected as necessary for differences in age, sex, and OA risk factors other than BMI. The overall prevalence of lesions was 64% for meniscus and 79% for cartilage (including low grade lesions). At baseline, the prevalence and severity of knee lesions was positively associated with BMI, with a nearly fourfold increase in meniscal tears and more than twofold increase in high-grade cartilage defects in obese individuals relative to normal-weight subjects. Over the 36-month follow-up period, the number of new or worsening cartilage lesions of any grade was significantly higher in obese subjects (p = 0.039), while there was no significant difference in meniscal lesion progression. Obesity was associated with both higher prevalence and severity of early degenerative changes in the knee in middle-aged individuals without radiographic OA and with significantly increased cartilage lesion progression (of any grade) over 36 months. (orig.)

  19. Obesity increases the prevalence and severity of focal knee abnormalities diagnosed using 3T MRI in middle-aged subjects - data from the osteoarthritis initiative

    International Nuclear Information System (INIS)

    To study the effect of BMI on the prevalence, severity, and 36-month progression of early degenerative changes in the knee by using 3T MRI in middle-aged subjects without radiographic osteoarthritis (OA). We examined baseline and 36-month follow-up MR studies from 137 middle-aged individuals (45-55 years old) with risk factors for knee OA but no radiographic OA from the Osteoarthritis Initiative. Subjects were grouped into three categories: normal BMI (BMI 2, n = 38), overweight (BMI 25-29.9 kg/m2, n = 37), and obese (BMI ≥ 30 kg/m2, n = 62). Using 3T MRI, cartilage, meniscus, and bone marrow abnormalities were graded using the OA Whole-organ MR Imaging Score (WORMS). The statistical analysis was corrected as necessary for differences in age, sex, and OA risk factors other than BMI. The overall prevalence of lesions was 64% for meniscus and 79% for cartilage (including low grade lesions). At baseline, the prevalence and severity of knee lesions was positively associated with BMI, with a nearly fourfold increase in meniscal tears and more than twofold increase in high-grade cartilage defects in obese individuals relative to normal-weight subjects. Over the 36-month follow-up period, the number of new or worsening cartilage lesions of any grade was significantly higher in obese subjects (p = 0.039), while there was no significant difference in meniscal lesion progression. Obesity was associated with both higher prevalence and severity of early degenerative changes in the knee in middle-aged individuals without radiographic OA and with significantly increased cartilage lesion progression (of any grade) over 36 months. (orig.)

  20. Levy Matrices and Financial Covariances

    Science.gov (United States)

    Burda, Zdzislaw; Jurkiewicz, Jerzy; Nowak, Maciej A.; Papp, Gabor; Zahed, Ismail

    2003-10-01

    In a given market, financial covariances capture the intra-stock correlations and can be used to address statistically the bulk nature of the market as a complex system. We provide a statistical analysis of three SP500 covariances with evidence for raw tail distributions. We study the stability of these tails against reshuffling for the SP500 data and show that the covariance with the strongest tails is robust, with a spectral density in remarkable agreement with random Lévy matrix theory. We study the inverse participation ratio for the three covariances. The strong localization observed at both ends of the spectral density is analogous to the localization exhibited in the random Lévy matrix ensemble. We discuss two competitive mechanisms responsible for the occurrence of an extensive and delocalized eigenvalue at the edge of the spectrum: (a) the Lévy character of the entries of the correlation matrix and (b) a sort of off-diagonal order induced by underlying inter-stock correlations. (b) can be destroyed by reshuffling, while (a) cannot. We show that the stocks with the largest scattering are the least susceptible to correlations, and likely candidates for the localized states. We introduce a simple model for price fluctuations which captures behavior of the SP500 covariances. It may be of importance for assets diversification.

  1. Dental caries prevalence in children up to 36 months of age attending daycare centers in municipalities with different water fluoride content

    Directory of Open Access Journals (Sweden)

    Ana Valéria Pagliari Tiano

    2009-02-01

    Full Text Available This study determined the prevalence of cavitated caries lesions (CCL and early childhood caries (ECC, and the contribution of some variables in children up to 36 months of age attending daycare centers in municipalities with different fluoride levels in the water supply: AFC (adequate fluoride content and LFC (low fluoride content. After approval of the Ethics Committee, the parents were interviewed. The children were clinically examined using the same codes and criteria established by the WHO (World Health Organization and the ADA (American Dental Association. Fisher's exact test (p<0.05 was applied for statistical analysis of data. The dmft indices calculated in the LFC and AFC municipalities were 0.57 and 0.68, respectively. Considering all children examined, 17.6% presented CCL and 33.8% ECC. The economic classification, mother's education level and duration of breastfeeding were considered statistically significant with regards to CCL prevalence. The age group, duration of the habit of drinking milk before bedtime and age at which oral hygiene started were considered statistically significant with regards to ECC prevalence.

  2. Prevalence and factors of addictive Internet use among adolescents in Wuhan, China: interactions of parental relationship with age and hyperactivity-impulsivity.

    Directory of Open Access Journals (Sweden)

    Xianhua Wu

    Full Text Available PURPOSES: This study examined the prevalence of addictive Internet use and analyzed the role of parental relationship in affecting this behavior among a random sample of adolescents in Wuhan, China. METHODS: Students (n = 1,101 were randomly selected from four schools, including 638 boys and 463 girls with a mean age of 13.8 (standard deviation = 1.2 years. Addictive Internet use, parental relationship, hyperactivity-impulsivity were measured by validated instruments. Prevalence rate, ANOVA and multiple linear regression method were used to analyze the level of Internet addiction and its association with parental relationship, hyperactivity-impulsivity, as well as the interaction of parental relationship with chronological age and hyperactivity-impulsivity. RESULTS: The prevalence rate of Internet addiction was 13.5% (16.5% for boys and 9.5% for girls, p<0.01. Compared to non-addictive users, addictive Internet users were scored significantly lower on parental relationships and significantly higher on hyperactivity-impulsivity. Interaction analysis indicated that better parental relationship was associated with more reductions in risk of addictive Internet use for younger students than for older students, and with more risk of Internet addiction among higher than among lower hyperactivity-impulsivity students. CONCLUSIONS: Findings of this study indicate that adolescent addictive Internet use is a significant public health threat in China. Prevention interventions targeting parental relationship must consider adolescent's age and hyperactivity-impulsivity tendency.

  3. The prevalence of probable migraine and sleep quality among women aged 20-49 living in a semi-rural area in western Turkey

    OpenAIRE

    Egemen Unal; Resat Aydin; Mehmet Enes Gokler; Alaettin Unsal

    2015-01-01

    Background: We aimed to evaluate the prevalence of probable migraine, to examine the factors associated with probable migraine and to assess the level of sleep quality among women aged 20-45 who were living in the county town named Mahmudiye, in Eskisehir, in Turkey. Methods: The study was carried out in all women aged 20-45 years in Mahmudiye. 69.2% of women (n=570) comprised the study group. Questionnaire consisted of three parts: The first part included several socio-demographic, nutri...

  4. Prevalence of impaired left ventricular systolic function and heart failure in a middle-aged and elderly urban population segment of Copenhagen

    DEFF Research Database (Denmark)

    Raymond, I.; Pedersen, F.; Steensgaard-Hansen, F.;

    2003-01-01

    . SETTING: The study population was recruited from general practitioners situated in the same urban area and examined in a university hospital in Copenhagen, Denmark. PARTICIPANTS: 764 participants (432 women and 332 men, median (SD) age 66 (11) years) participated. The study population was stratified......OBJECTIVE: To assess the prevalence of impaired left ventricular systolic function and manifest heart failure in a general population aged 50-89 years. DESIGN: In this cross sectional survey, participants filled in a heart failure questionnaire. ECG, blood tests, and echocardiography were performed.......6%). In the male population systolic heart failure (left ventricular ejection fraction

  5. Socioeconomic Status and Overweight Prevalence in Polish Adolescents: The Impact of Single Factors and a Complex Index of Socioeconomic Status in Respect to Age and Sex

    OpenAIRE

    Joanna Kowalkowska; Lidia Wadolowska; Justyna Weronika Wuenstel; Małgorzata Anna Słowińska; Ewa Niedźwiedzka

    2014-01-01

    Abstract Background The aim of this study was to analyze the association between overweight prevalence and socioeconomic status (SES) measured by complex SES index and single SES factors in Polish adolescents in respect to age and sex. Methods This cross-sectional study was conducted in 2010-2011. A total of 1,176 adolescents aged 13.0-18.9 years were included. The respondents were students of junior-high and high schools from northern, eastern and central Poland. Quota sampling by sex and ag...

  6. Report on Childhood Obesity in China (4) Prevalence and Trends of Overweight and Obesity in Chinese Urban School-age Children and Adolescents, 1985-2000

    Institute of Scientific and Technical Information of China (English)

    CHENG-YE JI; WORKING GROUP ON OBESITY IN CHINA (WGOC)

    2007-01-01

    Objective To describe the nationwide prevalence of childhood overweight/obesity, and their group variations and trends over the past 20 years in the Chinese urban population. Methods Data sets of boys and girls at the age of 7-18 years collected from the series of Chinese national surveillance on students' constitution and health (CNSSCH) between 1985 and 2000 were divided into five socioeconomic and demographic groups, while BMI classification reference proposed by Working Group on Obesity in China (WGOC) was used as screening reference to calculate the prevalence and trends of overweight/obesity in these groups. Results In 2000, the prevalence of obesity and overweight in boys aged 7-18 years was 11.3% and 6.5% in Beijing, 13.2% and 4.9% in Shanghai, 9.9% and 4.5% in coastal big cities, and 5.8% and 2.0% in coastal medium/small-sized cities, respectively, while the prevalence of of obesity and overweight in girls of the same age group was 8.2% and 3.7% in Beijing, 7.3% and 2.6% in Shanghai, 5.9% and 2.8% in coastal big cities, and 4.8% and 1.7% in coastal medium/small-sized cities, respectively. The prevalence of obesity was low in most of the inland cities at an early stage of epidemic overweight. The epidemic manifested a gradient distribution in groups, which was closely related to socioeconomic status (SES) of the study population. However, a dramatic and steady increasing trend was witnessed among all sex-age subgroups in the five urban groups, and such a trend was stronger in boys than in girls, and much stronger in children than in adolescents. Conclusion Although China is at an early stage of epidemic obesity by and large, the prevalence of obesity in her urban population, particularly in coastal big cities has reached the average level of developed countries. The increasing trend has been rapid since early 1990s, and the increments in obesity and overweight are exceptionally high. The prospect of epidemic obesity in China is in no way optimistic

  7. Covariance evaluation work at LANL

    Energy Technology Data Exchange (ETDEWEB)

    Kawano, Toshihiko [Los Alamos National Laboratory; Talou, Patrick [Los Alamos National Laboratory; Young, Phillip [Los Alamos National Laboratory; Hale, Gerald [Los Alamos National Laboratory; Chadwick, M B [Los Alamos National Laboratory; Little, R C [Los Alamos National Laboratory

    2008-01-01

    Los Alamos evaluates covariances for nuclear data library, mainly for actinides above the resonance regions and light elements in the enUre energy range. We also develop techniques to evaluate the covariance data, like Bayesian and least-squares fitting methods, which are important to explore the uncertainty information on different types of physical quantities such as elastic scattering angular distribution, or prompt neutron fission spectra. This paper summarizes our current activities of the covariance evaluation work at LANL, including the actinide and light element data mainly for the criticality safety study and transmutation technology. The Bayesian method based on the Kalman filter technique, which combines uncertainties in the theoretical model and experimental data, is discussed.

  8. Covariant jump conditions in electromagnetism

    CERN Document Server

    Itin, Yakov

    2014-01-01

    A generally covariant four-dimensional representation of Maxwell's electrodynamics in a generic material medium can be achieved straightforwardly in the metric-free formulation of electromagnetism. In this setup, the electromagnetic phenomena described by two tensor fields, which satisfy Maxwell's equations. A generic tensorial constitutive relation between these fields is an independent ingredient of the theory. By use of different constitutive relations (local and non-local, linear and non-linear, etc.), a wide area of applications can be covered. In the current paper, we present the jump conditions for the fields and for the energy-momentum tensor on an arbitrarily moving surface between two media. From the differential and integral Maxwell equations, we derive the covariant boundary conditions, which are independent of any metric and connection. These conditions include the covariantly defined surface current and are applicable to an arbitrarily moving smooth curved boundary surface. As an application of ...

  9. Prevalence and risk factors for penile lesions/anomalies in a cohort of Brazilian men ≥ 40 years of age

    Directory of Open Access Journals (Sweden)

    Frederico R Romero

    2013-01-01

    Full Text Available Purpose To report the prevalence and risk factors of penile lesions/anomalies in a Metropolitan Brazilian city. Materials and Methods All participants undergoing prostate cancer screening in the city of Curitiba were systematically examined to identify penile lesions including cutaneous mycosis, sexually transmitted diseases, penile cancer, meatal stenosis, hypospadias, and Peyronie's disease. Outcomes of interest included the prevalence and the relative risk and 95% confidence intervals of the lesions/anomalies according to age, school level, race, personal history of diabetes, arterial hypertension, nonspecific urethritis, and vasectomy. Results Balanoposthitis occurred in 11.8% of all participants, with an increased risk in those with diabetes (RR = 1.73, or past history of nonspecific urethritis (RR = 1.58; tinea of the penis was present in 0.2%; condyloma acuminata in 0.5%; herpes virus infection in 0.4%; urethral discharge in 0.2%; genital vitiligo in 0.7%, with an increased prevalence in non-white men (RR = 4.43, and in subjects with lower school level (RR = 7.24; phimosis in 0.5%, with a nearly 7-fold increased risk in diabetics; lichen sclerosus in 0.3%; stenosis of the external urethral meatus in 0.7%, with a higher prevalence in subjects with lichen sclerosus (RR = 214.9, and in those older than 60 years of age (RR = 3.57; hypospadia in 0.6%; fibrosis suggestive of Peyronie's disease in 0.9%, especially in men older than 60 years (RR = 4.59 and with diabetes (RR = 3.91; and penile cancer in 0.06%. Conclusion We estimated the prevalence and risk factors of commonly seen penile diseases in an adult cohort of Brazilian men.

  10. [Gender and age characteristics and the trends in prevalence of obesity in the adult population in Russia during the 1994-2012 period].

    Science.gov (United States)

    Martinchik, A N; Baturin, A K; Keshabyants, E E; Peskova, E V

    2015-01-01

    The analysis of the prevalence of overweight and obesity in adult age and sex groups of the Russian population in the dynamics of observation from 1994 to 2012 was based on anthropometric measurements of weight and height in Russian Longitudinal Monitoring Survey. The mean values of body mass index (BMI) and the frequency of obesity (BMI > 30.0) of the entire population have been increased during the observation period. The analyzing the data by gender revealed a significant increase in the frequency of obesity mainly among men, especially in the period 2005-2012, whereas among women increased incidence of obesity was negligible. The most rapid increase in the frequency of overweight and obesity in men noted in the age period of 20-30 years, and further increase in frequency of overweight and obesity with age were negligible. The rate of overweight and obesity in women had almost linear increase in the age period of 20-60 years. Comparative analysis of the prevalence of obesity showed that the obtained values for the 2000-2012 period were close to those characteristic of the developed world in recent decades. The growth of obesity rate in the general adult population in 2000-2005 and the 2005-2012 was 0.4% per year. At the same time, men showed a significant acceleration of the growth rate of obesity in the period 2005 to 2012 (0.61% per year) compared with the period 2000-2005 (0.44% per year). Increase in the frequency of obesity was observed in all regions in 2000 to 2012. The data should be considered as a rationale for research into the causes of gender differences in the prevalence of overweight and obesity in the first place to find differences in the peculiarities of dietary intake between men and women at different ages of life, leading to the development of overweight and obesity.

  11. Cosmic Censorship Conjecture revisited: Covariantly

    CERN Document Server

    Hamid, Aymen I M; Maharaj, Sunil D

    2014-01-01

    In this paper we study the dynamics of the trapped region using a frame independent semi-tetrad covariant formalism for general Locally Rotationally Symmetric (LRS) class II spacetimes. We covariantly prove some important geometrical results for the apparent horizon, and state the necessary and sufficient conditions for a singularity to be locally naked. These conditions bring out, for the first time in a quantitative and transparent manner, the importance of the Weyl curvature in deforming and delaying the trapped region during continual gravitational collapse, making the central singularity locally visible.

  12. Prevalence of Helicobacter Pylori Infection in School and Pre-School Aged Children with C-14 Urea Breath Test and the Association with Familial and Environmental Factors

    Science.gov (United States)

    Çınar, Alev; Sadıç, Murat; İkbal Atılgan, Hasan; Baskın, Aylin; Koca, Gökhan; Demirel, Koray; Korkmaz, Meliha

    2015-01-01

    Objective: To investigate the prevalence of Helicobacter pylori (Hp) infection in pre-school and school age children with C-14 urea breath test, and to explore its association with age and socioeconomic factors in Turkey. Methods: Hp infection status was determined by using Urea Breath Test (UBT). Patients who had previous gastric surgery, Hp eradication treatment or equivocal UBT results were excluded. A questionnaire was administered to elicit information on gender, age, ABO/Rh blood group type, presence of gastric disease in the family, domestic animal in the household, and treatment for idiopathic Iron Deficiency Anemia (IDA). Results: This retrospective study included 500 pediatric patients (179 boys, 321 girls, mean age 10.7±4.3 years) of whom 62 (12.4%) were aged ≤6 years and 438 (87.6%) were aged 7 to 16 years. Helicobacter pylori (Hp) was positive in 245 (49%) cases. In the pre-school age group, 21/62 cases (34%) had positive UBT while in the school age group 224/438 children (51%) had positive UBT. A family history of dyspepsia and pet ownership were not associated with Hp positivity. Hp positive 76 (29.8%) children were on IDA treatment but this was not statistically significant. Conclusion: The Hp infection positivity rate was 49% in the pediatric age study group. The positivity rate was significantly lower at preschool age than school age, and it increased with age. There was no association with gender, ABO/Rh blood groups, presence of domestic pets, IDA, or history of gastric disease in the family. PMID:26316471

  13. Stunting, Underweight and Overweight in Children Aged 2.0-4.9 Years in Indonesia: Prevalence Trends and Associated Risk Factors.

    Directory of Open Access Journals (Sweden)

    Cut Novianti Rachmi

    Full Text Available The double burden of malnutrition affects many low and middle-income countries. This study aimed to: a determine temporal trends in the prevalence of underweight, stunting, and at risk of overweight/ overweight or obesity in Indonesian children aged 2.0-4.9 years; and b examine associated risk factors.A repeated cross-sectional survey. This is a secondary data analysis of waves 1, 2, 3, and 4 (1993, 1997, 2000, and 2007 of the Indonesian Family Life Survey, which includes 13 out of 27 provinces in Indonesia. Height, weight and BMI were expressed as z-scores (2006 WHO Child Growth Standards. Weight-for-age-z-score +1, >+2, >+3 as at-risk, overweight and obese, respectively.There are 938, 913, 939, and 1311 separate children in the 4 waves, respectively. The prevalence of stunting decreased significantly from waves 1 to 4 (from 50.8% to 36.7%, as did the prevalence of underweight (from 34.5% to 21.4%. The prevalence of 'at-risk'/overweight/obesity increased from 10.3% to 16.5% (all P<0.01. Stunting and underweight were related to lower birth weight, being breastfed for 6 months or more, having parents who were underweight or had short stature, and mothers who never attended formal education. Stunting was also higher in rural areas. Being at-risk, or overweight/obese were closely related to being in the youngest age group (2-2·9 years or male, having parents who were overweight/obese or having fathers with university education.The double burden of malnutrition occurs in Indonesian children. Development of policy to combine the management of chronic under-nutrition and over-nutrition is required.

  14. The prevalence of Nonsuicidal Self-Injury (NSSI among high school students in relation to age and sex.

    Directory of Open Access Journals (Sweden)

    Halina Kądziela-Olech

    2015-08-01

    Conducting further research in the area of NSSI seems to be crucial due to chronicity and prevalence as well as the fact that numerous repeated self-injuries bringing relief or causing positive state of mind might indicate a mechanism similar to an addiction syndrome in adolescence.

  15. Prevalence and correlates of bullying perpetration and victimization among school-aged youth with intellectual disabilities: A systematic review.

    Science.gov (United States)

    Maïano, Christophe; Aimé, Annie; Salvas, Marie-Claude; Morin, Alexandre J S; Normand, Claude L

    2016-01-01

    Recent literature reviews show that bullying perpetration and victimization are major public health concerns for typically developing (TD) youth. Nevertheless, the magnitude of this phenomenon among youth with intellectual disabilities (ID) remains unclear. Therefore, the purpose of this review is to provide a synthesis of the empirical studies examining the prevalence and correlates of bullying perpetration and victimization among youth with ID. A systematic literature search was performed and 11 studies met the inclusion criteria. The findings from these studies showed weighted mean prevalence rates of general bullying perpetration, bullying victimization and both of 15.1%, 36.3%, and 25.2%, respectively. Weighted mean prevalence rates of bullying perpetration and victimization differed according to the characteristics of the studies (e.g., assessment context, school setting, information source, type of measures, time frame). Additionally, high weighted mean prevalence rates of physical (33.3%), verbal (50.2%), relational (37.4%), and cyber (38.3%) victimization were found among youth with ID. When youth with ID were compared to youth with other disabilities or TD peers, no clear differences were found. Finally, the present review shows that correlates of bullying perpetration and victimization in this population remain understudied.

  16. Prevalence and Associated Factors of Secondhand Smoke Exposure among Internal Chinese Migrant Women of Reproductive Age: Evidence from China's Labor-Force Dynamic Survey.

    Science.gov (United States)

    Gong, Xiao; Luo, Xiaofeng; Ling, Li

    2016-04-01

    Secondhand smoke (SHS) is a major risk factor for poor health outcomes among women in China, where proportionately few women smoke. This is especially the case as it pertains to women's reproductive health, specifically migrant women who are exposed to SHS more than the population at large. There are several factors which may increase migrant women's risk of SHS exposure. This paper aims to investigate the prevalence and associated factors of SHS exposure among internal Chinese migrant women of reproductive age. The data used were derived from the 2014 Chinese Labor Dynamic Survey, a national representative panel survey. The age-adjusted rate of SHS exposure of women of reproductive age with migration experience was of 43.46% (95% CI: 40.73%-46.40%), higher than those without migration experience (35.28% (95% CI: 33.66%-36.97%)). Multivariate analysis showed that participants with a marital status of "Widowed" had statistically lower exposure rates, while those with a status of "Cohabitation" had statistically higher exposure. Those with an undergraduate degree or above had statistically lower SHS exposure. Those with increasing levels of social support, and those who currently smoke or drink alcohol, had statistically higher SHS exposure. Participants' different work-places had an effect on their SHS exposure, with outdoor workers statistically more exposed. Our findings suggest that urgent tobacco control measures should be taken to reduce smoking prevalence and SHS exposure. Specific attention should be paid to protecting migrant women of reproductive age from SHS. PMID:27043604

  17. Prevalence of intestinal parasitic infections among children under five years of age with emphasis on Schistosoma mansoni in Wonji Shoa Sugar Estate, Ethiopia.

    Directory of Open Access Journals (Sweden)

    Yirgalem G/hiwot

    Full Text Available Intestinal parasite infections are major public health problems of children in developing countries causing undernutrition, anemia, intestinal obstruction and mental and physical growth retardation. This study was conducted to assess the prevalence of intestinal helminthic infections among children under five years of age with emphasis on Schistosoma mansoni in Wonji Shoa Sugar Estate, Ethiopia. A cross-sectional parasitological survey was conducted in under-five children living in Wonji Shoa Sugar Estate Ethiopia, April, 2013. Stool samples were collected and examined for intestinal parasites using single Kato-Katz and single Sodium acetate-acetic acid-formalin (SAF solution concentration methods. Out of 374 children examined using single Kato-Katz and single SAF-concentration methods, 24.3% were infected with at least one intestinal parasite species. About 10.4%, 8.8%, 4.6%, 2.9%, 1.6% and 0.8% of the children were infected with Hymenolepis nana, Schistosoma mansoni, Ascaris lumbricoides, Trichuris trichiura, Enterobius vermicularis and hookworm, respectively. Prevalence of double, triple and quadruple intestinal helminthic infection was 6.4%, 0.54% and 1.1%, respectively. A significant increase in prevalence of S. mansoni (8.3% versus 3.2% and T. trichiura (2.7% versus 0.5% infection was observed when determined via the single Kato-Katz method compared to the prevalence of the parasites determined via the single SAF-concentration method. On the other hand, the single SAF-concentration method (9.1% revealed a significantly higher prevalence of H. nana infection than the single Kato-Katz (1.6% does. In conclusion, intestinal helminths infections particularly S. mansoni and H. nana were prevalent in under-five children of Wonji Shoa Sugar Estate. Including praziquantel treatment in the deworming program as per the World Health Organization guidelines would be vital to reduce the burden of these diseases in areas where S. mansoni and H. nana

  18. Relativistic covariance of Ohm's law

    CERN Document Server

    Starke, R

    2014-01-01

    The derivation of relativistic generalizations of Ohm's law has been a long-term issue in theoretical physics with deep implications for the study of relativistic plasmas in astrophysics and cosmology. Here we propose an alternative route to this problem by introducing the most general Lorentz covariant first order response law, which is written in terms of the fundamental response tensor $\\chi^\\mu_{~\

  19. Prevalence of self-reported pain, joint complaints and knee or hip complaints in adults aged ≥ 40 years: a cross-sectional survey in Herne, Germany.

    Directory of Open Access Journals (Sweden)

    Ulrich Thiem

    Full Text Available BACKGROUND: Pain and musculoskeletal complaints are among the most common symptoms in the general population. Despite their epidemiological, clinical and health economic importance, prevalence data on pain and musculoskeletal complaints for Germany are scarce. METHODS: A cross-sectional survey of a random sample of citizens of Herne, Germany, aged ≥ 40 years was performed. A detailed self-complete postal questionnaire was used, followed by a short reminder questionnaire and telephone contacts for those not responding. The questionnaire contained 66 items, mainly addressing pain of any site, musculoskeletal complaints of any site and of knee and hip, pain intensities, the Western Ontario MacMaster Universities (WOMAC index, medication, health care utilization, comorbidities, and quality of life. RESULTS: The response rate was 57.8% (4,527 of 7,828 individuals. Survey participants were on average 1.3 years older, and the proportion of women among responders tended to be greater than in the population sample. There was no age difference between the population sample and 2,221 participants filling out the detailed questionnaire. The following standardized prevalences were assessed: current pain: 59.7%, pain within the past four weeks: 74.5%, current joint complaints: 49.3%, joint complaints within the past four weeks and twelve month: 62.8% and 67.4%, respectively, knee as the site predominantly affected: 30.9%, knee bilateral: 9.7%, hip: 15.2%, hip bilateral: 3.5%, knee and hip: 5.5%. Pain and musculoskeletal complaints were significantly more often reported by women. A typical relationship of pain and joint complaints to age could be found, i.e. increasing prevalences with increasing age categories, with a drop in the highest age groups. In general, pain and joint pain were associated with comorbidity and body mass index as well as quality of life. CONCLUSIONS: Our data confirm findings of other recent national as well as European surveys. The

  20. Prevalence of purging at age 16 and associations with negative outcomes among girls in three community-based cohorts

    OpenAIRE

    Solmi, Francesca; Sonneville, Kendrin R.; Easter, Abigail; Horton, Nicholas J.; Crosby, Ross D; Treasure, Janet; Rodriguez, Alina; Jarvelin, Marjo-Riitta; Field, Alison E.; Micali, Nadia

    2014-01-01

    Background: The comorbidity of purging behaviours, such as vomiting, inappropriate use of laxatives, diuretics or slimming medications, has been examined in literature. However, most studies do not include adolescents, individuals who purge in the absence of binge eating, or those purging at subclinical frequency. This study examines the prevalence of purging among 16-year-old girls across three countries and their association with substance use and psychological comorbidity.Methods: Data wer...

  1. Prevalence of HHV-6 in cerebrospinal fluid of children younger than 2 years of age with febrile convulsion.

    OpenAIRE

    Setareh Mamishi; Laura Kamrani; Masoud Mohammadpour; Jila Yavarian

    2014-01-01

    Background and Objective Febrile convulsion is a common disorder in children. Viral infections such as human herpes virus 6 (HHV-6) which results in roseola infantum may contribute to developing seizure. The objective of this study was to determine the prevalence of HHV-6 by detecting DNA in cerebrospinal fluid (CSF) of children with febrile convulsion and without any rash of roseola infantum. Materials and Methods In this descriptive cross-sectional study, CSF of 100 children younger than 2 ...

  2. Prevalence and associated risk factors of under nutrition among children aged 6 to 59 months in internally displaced persons of jalozai camp, District Nowshera, Khyber Pakhtunkhwa

    International Nuclear Information System (INIS)

    Background: The magnitude of under nutrition among children below five years of age is high in Pakistan. Undernutrition and infections are the two most important factors that affect the growth of children. This study explains the extent of undernutrition and prevalence of wasting and stunting among preschool children. Method: This cross sectional study with a sample size of 446 covered the age group 6-59 months in Jalozai Camp, District Nowshera. Height for age, weight for age and weight for height were measured as per WHO guidelines. Systematic random sampling technique was used for sample selection. Data was collected using a questionnaire. Results: According to height for age Z-score, out of 446 children studied, 8.5 percentage were stunted and 4.0 percentage were severely stunted. According to weight for age Z score, 11.4 percentage were underweight and 3.6 percentage were severely underweight. According to weight for height Z-score, 4.0 percentage were wasted and 2.7 percentage were severely wasted. Conclusion: The undernutrition in children is comparable to the national figures. Although our study found that absence of formal education, big family size, late and early weaning, absence of exclusive breast feeding and poverty were the factors associated with undernutrition in children, they could cause increase in under nutrition in future if not improved. (author)

  3. PREVALENCE OF CHRONIC CONSTIPATION AND ITS PSYCHOSOCIAL IMPACT ON CHILDREN AGED BETWEEN 4 TO 14 YEARS AND THEIR PARENTS : A HOSPITAL BASED CROSS - SECTIONAL STUDY

    Directory of Open Access Journals (Sweden)

    Madhu

    2015-08-01

    Full Text Available BACKGROUND: Gastrointestinal functional disorders especially constipation cause morbidity in otherwise healthy children with an estimated prevalence of 1% to 30%. It is perceived as a benign, easily treatable condition however left untreated, can lead to complication s ( F aecal impaction, incontinence and bowel perforations. Only a small proportion of patients seek medical advice; thus, the exact prevalence of the disorder is difficult to estimate. AIMS: To estimate the prevalence of chronic functional constipation in children aged 4 - 14 years and the degree of psychosocial impact on children and their parents. SETTINGS AND DESIGN: This cross - sectional study was carried out at K.R and Cheluvamba Hospital, MMC &RI, MYSORE from 1st FEB 2014 to 31ST MAY, 2014. METHODS AND MATERIAL: Constipation was defined using Rome III criteria. Children with organic causes of chronic constipation were excluded. Abdominal pain, fecal mass, anorexia, fecal soiling, withholding behavior were recorded. Psychosocial impact on children and par ents was assessed using Paediatric Quality Of Life Inventory (PQLI and modified PIP Questionnaires. Scoring done according to instructions given with respective questionnaires. STATISTICAL ANALYSIS: Prevalence was calculated using rates, ratios and percen tages. Tests of significance were performed wherever relevant. P value of less than 0.05 was considered significant. RESULTS: The prevalence of functional constipation was estimated to be 14.29% with higher prevalence in females as compared to males i.e. 1 6.19% vs. 13.42%. Perineal soiling was significantly associated with functional constipation i.e. 58.33%. Mean score of all children was 75.4 and 70.6 for physical and psychosocial impact. 88% children reported PQLI score <80(Mean 69.4. No difference betw een male and female child (p=.614. 83.33% parents reported score <80(Mean 69.3. No significant difference on psychosocial impact and quality of life according to PQLI

  4. The reminiscence bump for public events: A review of its prevalence and taxonomy of alternative age distributions

    DEFF Research Database (Denmark)

    Koppel, Jonathan Mark

    2013-01-01

    the bump, with a number of alternative age distributions seen in the literature. Therefore, I present a taxonomy of these alternative age distributions. Lastly, I discuss the implications of the existing literature regarding the mechanisms underlying the bump and offer suggestions for future research....

  5. Punishment and reward in parental discipline for children aged 5 to 6 years : prevalence and groups at risk

    NARCIS (Netherlands)

    Theunissen, Meinou H. C.; Vogels, Anton G. C.; Reijneveld, Sijmen A.

    2014-01-01

    OBJECTIVE: In this study we examined the use and predictors of different discipline practices by parents of children aged 5 to 6 years. METHODS: We obtained cross-sectional data for a nationally representative Dutch sample of children aged 5 to 6 years within the setting of routine well-child visits

  6. Prevalence and risk factors for vitamin C deficiency in north and south India: a two centre population based study in people aged 60 years and over.

    Directory of Open Access Journals (Sweden)

    Ravilla D Ravindran

    Full Text Available BACKGROUND: Studies from the UK and North America have reported vitamin C deficiency in around 1 in 5 men and 1 in 9 women in low income groups. There are few data on vitamin C deficiency in resource poor countries. OBJECTIVES: To investigate the prevalence of vitamin C deficiency in India. DESIGN: We carried out a population-based cross-sectional survey in two areas of north and south India. Randomly sampled clusters were enumerated to identify people aged 60 and over. Participants (75% response rate were interviewed for tobacco, alcohol, cooking fuel use, 24 hour diet recall and underwent anthropometry and blood collection. Vitamin C was measured using an enzyme-based assay in plasma stabilized with metaphosphoric acid. We categorised vitamin C status as deficient (28 µmol/L. We investigated factors associated with vitamin C deficiency using multivariable Poisson regression. RESULTS: The age, sex and season standardized prevalence of vitamin C deficiency was 73.9% (95% confidence Interval, CI 70.4,77.5 in 2668 people in north India and 45.7% (95% CI 42.5,48.9 in 2970 from south India. Only 10.8% in the north and 25.9% in the south met the criteria for adequate levels. Vitamin C deficiency varied by season, and was more prevalent in men, with increasing age, users of tobacco and biomass fuels, in those with anthropometric indicators of poor nutrition and with lower intakes of dietary vitamin C. CONCLUSIONS: In poor communities, such as in our study, consideration needs to be given to measures to improve the consumption of vitamin C rich foods and to discourage the use of tobacco.

  7. Age associated differences in prevalence of individual rotterdam criteria and metabolic risk factors during reproductive age in 446 caucasian women with polycystic ovary syndrome

    DEFF Research Database (Denmark)

    Glintborg, D; Mumm, H; Ravn, P;

    2012-01-01

    Clinical manifestations and metabolic risk factors may differ according to age in patients with polycystic ovary syndrome (PCOS). Therefore, a retrospective trans-sectional study in academic tertiary-care medical center was designed. A cohort of 446 premenopausal, Caucasian women (age range 15......-49 years) with PCOS were divided into 4 subgroups according to age: group 1 (15-19 years, n=42), group 2 (20-29 years, n=180), group 3 (30-39 years, n=187), group 4 (40-49 years, n=37) and underwent clinical evaluation (Ferriman-Gallwey score, BMI, waist, blood pressure), hormone analyses (sex hormones......, fasting lipids, insulin, glucose), transvaginal ultrasound, oral glucose tolerance tests (OGTT) (n=234), and ACTH tests (n=201). BMI, waist, Ferriman-Gallwey score, blood pressure, and lipid profile were higher in older vs. younger age groups whereas androgen levels were lower. Measures of insulin...

  8. Prevalence and age-of-onset distributions of DSM IV mental disorders and their severity among school going Omani adolescents and youths: WMH-CIDI findings

    Directory of Open Access Journals (Sweden)

    Morsi Magdi

    2009-09-01

    Full Text Available Abstract Background There is a dearth of studies exploring the magnitude of mental disorders amongst adolescents and youths in the Arab world. To our knowledge, this phase 2 survey in Oman is the first nationally representative school-based study to determine the prevalence of DSM-IV mental disorders (lifetime and over the preceding 12 months, their age-of-onset distributions and determine their severity over the past 12 months using the World Mental Health-Composite International Diagnostic Interview, the WMH-CIDI, used for international comparison. Methods A total of 1,682 (91.61% students out of 1836 students who formed the phase 2 random sub-sample of a multi-stage, stratified, random sampling design (phase 1, participated in the face-to-face structured interview using the Arabic-version of WMH-CIDI 3.0. Results The phase 1 results using the General Health Questionnaire (GHQ-12 and Child Depression Inventory (CDI showed depressive symptoms to be 17% prevalent in the larger sample of 5409 adolescents and youths. Amongst the phase 2 respondents from this sample, 13.9% had at least one DSM IV diagnostic label. The lifetime prevalence of Major Depressive Disorder (MDD was 3.0%; Bipolar Mood Disorder (BMD was 1%, Specific phobia 5.8% and Social phobia 1.6%. The female gender was a strong predictor of a lifetime risk of MDD (OR 3.3, 95% CI 1.7-6.3, p = 0.000; Any Mood Disorders (OR 2.5, 95% CI 1.4-4.3, p = 0.002 and Specific Phobia (OR 1.5, 95% CI 1.0-2.4, p = 0.047. The severity of illness for cases diagnosed with 12 month DSM IV disorders was found to be 80% lower in females (OR 0.2, 95%CI 0.0-0.8. The estimates over the previous 12 month period when compared with the lifetime prevalence showed a 25% to 40% lower prevalence for MDD, Specific phobia, Social phobia, Any Anxiety Disorders (AAD and Any Mood disorders (AMD while the rate was 80% lower for Separation Anxiety Disorder/Adult Separation Anxiety (SAD/ASA. Mood disorders were significantly

  9. Baseline prevalence of abdominal aortic aneurysm, peripheral arterial disease and hypertension in men aged 65-74 years from a population screening study (VIVA trial)

    DEFF Research Database (Denmark)

    Grøndal, Nikolaj Fibiger; Søgaard, Rikke; Lindholt, Jes S.

    2015-01-01

    (PAD) and possible hypertension (HT), and detection rates. METHODS: This observational study was based on the intervention arm of a screening trial in 25 083 Danish men aged 65-74 years. A combined screening programme for AAA, PAD and HT was offered at local hospitals. Participants with positive test...... treatment was initiated in 34·8 per cent of the participants. CONCLUSION: Preventive actions were started in one-third of the attenders. The long-term effect of this on morbidity and mortality is an important part of future analysis. The trial confirms that the prevalence of AAA in Denmark has decreased...

  10. Prevalence and associated factors of dry eye: Our experience in patients above 40 years of age at a Tertiary Care Center

    OpenAIRE

    Suchi Shah; Harsha Jani

    2015-01-01

    Context: Dry eye is a very common as well as under-diagnosed ocular disorder. It is not only troublesome in terms of its symptoms but also imposes a great financial burden. Aims: To determine the prevalence of dry eye in ophthalmology out-patients at a Tertiary Care Hospital and its association with various clinico-epidemiological factors. Settings and Design: A hospital-based study at a Tertiary Care Center was conducted including 400 out-patients of age 40 years and above. Material...

  11. Cruel Intentions? HIV Prevalence and Criminalization During an Age of Mass Incarceration, U.S. 1999 to 2012

    Science.gov (United States)

    Sykes, Bryan L.; Hoppe, Trevor A.; Maziarka, Kristen D.

    2016-01-01

    Abstract A 2014 U.S. Department of Justice Best Practices Report advocates that states eliminate HIV-specific criminal penalties except under 2 conditions: when a human immunodeficiency virus (HIV)-positive person intentionally commits a sex crime or transmits the virus by engaging in behavior that poses a significant risk of transmission, regardless of actual transmission. We assess the premise of these exceptions to understand whether these best practices are based on scientific evidence about the population at risk of infection and the risk of sexual violence by HIV-positive individuals. We employ nationally representative, cross-sectional survey data from the Current Population Survey (CPS), the Survey of Inmates in State, Federal, and Local Jails (SISFLJ), and the National Health and Nutrition Survey (NHANES). Data from the CPS, SISFLJ, and NHANES are weighted and combined to analyze bias in the population at risk of HIV. Linear probability models are employed to estimate the likelihood that HIV-positive inmates are incarcerated for violent or sexual offenses, net of socioeconomic factors. We find significant measurement bias in HIV prevalence rates. The selection of national surveys for population denominators distorts contemporary estimates of HIV prevalence by 7% to 20%. Our findings also illustrate that HIV-positive inmates are 10 percentage-points less likely to be incarcerated for violent offenses than HIV-negative inmates. National best practice guidelines may undermine effective social policy that aims to curtail stigma within HIV-positive communities because scientific evidence neither include inmates into prevalence denominators (as a measure of the population at risk) nor assess the likelihood that HIV-positive inmates commit violent or sexual crimes. PMID:27100418

  12. Cruel Intentions? HIV Prevalence and Criminalization During an Age of Mass Incarceration, U.S. 1999 to 2012.

    Science.gov (United States)

    Sykes, Bryan L; Hoppe, Trevor A; Maziarka, Kristen D

    2016-04-01

    A 2014 U.S. Department of Justice Best Practices Report advocates that states eliminate HIV-specific criminal penalties except under 2 conditions: when a human immunodeficiency virus (HIV)-positive person intentionally commits a sex crime or transmits the virus by engaging in behavior that poses a significant risk of transmission, regardless of actual transmission. We assess the premise of these exceptions to understand whether these best practices are based on scientific evidence about the population at risk of infection and the risk of sexual violence by HIV-positive individuals. We employ nationally representative, cross-sectional survey data from the Current Population Survey (CPS), the Survey of Inmates in State, Federal, and Local Jails (SISFLJ), and the National Health and Nutrition Survey (NHANES). Data from the CPS, SISFLJ, and NHANES are weighted and combined to analyze bias in the population at risk of HIV. Linear probability models are employed to estimate the likelihood that HIV-positive inmates are incarcerated for violent or sexual offenses, net of socioeconomic factors. We find significant measurement bias in HIV prevalence rates. The selection of national surveys for population denominators distorts contemporary estimates of HIV prevalence by 7% to 20%. Our findings also illustrate that HIV-positive inmates are 10 percentage-points less likely to be incarcerated for violent offenses than HIV-negative inmates. National best practice guidelines may undermine effective social policy that aims to curtail stigma within HIV-positive communities because scientific evidence neither include inmates into prevalence denominators (as a measure of the population at risk) nor assess the likelihood that HIV-positive inmates commit violent or sexual crimes. PMID:27100418

  13. Piecewise linear regression splines with hyperbolic covariates

    International Nuclear Information System (INIS)

    Consider the problem of fitting a curve to data that exhibit a multiphase linear response with smooth transitions between phases. We propose substituting hyperbolas as covariates in piecewise linear regression splines to obtain curves that are smoothly joined. The method provides an intuitive and easy way to extend the two-phase linear hyperbolic response model of Griffiths and Miller and Watts and Bacon to accommodate more than two linear segments. The resulting regression spline with hyperbolic covariates may be fit by nonlinear regression methods to estimate the degree of curvature between adjoining linear segments. The added complexity of fitting nonlinear, as opposed to linear, regression models is not great. The extra effort is particularly worthwhile when investigators are unwilling to assume that the slope of the response changes abruptly at the join points. We can also estimate the join points (the values of the abscissas where the linear segments would intersect if extrapolated) if their number and approximate locations may be presumed known. An example using data on changing age at menarche in a cohort of Japanese women illustrates the use of the method for exploratory data analysis. (author)

  14. Discrete Symmetries in Covariant LQG

    CERN Document Server

    Rovelli, Carlo

    2012-01-01

    We study time-reversal and parity ---on the physical manifold and in internal space--- in covariant loop gravity. We consider a minor modification of the Holst action which makes it transform coherently under such transformations. The classical theory is not affected but the quantum theory is slightly different. In particular, the simplicity constraints are slightly modified and this restricts orientation flips in a spinfoam to occur only across degenerate regions, thus reducing the sources of potential divergences.

  15. Shrinkage Estimators for Covariance Matrices

    OpenAIRE

    Daniels, Michael J.; Kass, Robert E.

    2001-01-01

    Estimation of covariance matrices in small samples has been studied by many authors. Standard estimators, like the unstructured maximum likelihood estimator (ML) or restricted maximum likelihood (REML) estimator, can be very unstable with the smallest estimated eigenvalues being too small and the largest too big. A standard approach to more stably estimating the matrix in small samples is to compute the ML or REML estimator under some simple structure that involves estimation of fewer paramet...

  16. Quantum covariant c-map

    OpenAIRE

    Alexandrov, Sergei

    2007-01-01

    We generalize the covariant c-map found in hep-th/0701214 including perturbative quantum corrections. We also perform explicitly the superconformal quotient from the hyperkahler cone obtained by the quantum c-map to the quaternion-Kahler space, which is the moduli space of hypermultiplets. As a result, the perturbatively corrected metric on the moduli space is found in a simplified form comparing to the expression known in the literature.

  17. Are Maxwell's equations Lorentz-covariant?

    CERN Document Server

    Redzic, D V

    2016-01-01

    The statement that Maxwell's electrodynamics in vacuum is already covariant under Lorentz transformations is commonplace in the literature. We analyse the actual meaning of that statement and demonstrate that Maxwell's equations are perfectly fit to be Lorentz-covariant; they become Lorentz-covariant if we construct to be so, by postulating certain transformation properties of field functions. In Aristotelian terms, the covariance is a plain potentiality, but not necessarily entelechy.

  18. Covariant Perturbations of Schwarzschild Black Holes

    OpenAIRE

    Clarkson, Chris A.; Barrett, Richard K.

    2002-01-01

    We present a new covariant and gauge-invariant perturbation formalism for dealing with spacetimes having spherical symmetry (or some preferred spatial direction) in the background, and apply it to the case of gravitational wave propagation in a Schwarzschild black hole spacetime. The 1+3 covariant approach is extended to a `1+1+2 covariant sheet' formalism by introducing a radial unit vector in addition to the timelike congruence, and decomposing all covariant quantities with respect to this....

  19. The H-Covariant Strong Picard Groupoid

    OpenAIRE

    Jansen, Stefan; Waldmann, Stefan

    2004-01-01

    The notion of H-covariant strong Morita equivalence is introduced for *-algebras over C = R(i) with an ordered ring R which are equipped with a *-action of a Hopf *-algebra H. This defines a corresponding H-covariant strong Picard groupoid which encodes the entire Morita theory. Dropping the positivity conditions one obtains H-covariant *-Morita equivalence with its H-covariant *-Picard groupoid. We discuss various groupoid morphisms between the corresponding notions of the Picard groupoids. ...

  20. Covariant jump conditions in electromagnetism

    Science.gov (United States)

    Itin, Yakov

    2012-02-01

    A generally covariant four-dimensional representation of Maxwell's electrodynamics in a generic material medium can be achieved straightforwardly in the metric-free formulation of electromagnetism. In this setup, the electromagnetic phenomena are described by two tensor fields, which satisfy Maxwell's equations. A generic tensorial constitutive relation between these fields is an independent ingredient of the theory. By use of different constitutive relations (local and non-local, linear and non-linear, etc.), a wide area of applications can be covered. In the current paper, we present the jump conditions for the fields and for the energy-momentum tensor on an arbitrarily moving surface between two media. From the differential and integral Maxwell equations, we derive the covariant boundary conditions, which are independent of any metric and connection. These conditions include the covariantly defined surface current and are applicable to an arbitrarily moving smooth curved boundary surface. As an application of the presented jump formulas, we derive a Lorentzian type metric as a condition for existence of the wave front in isotropic media. This result holds for ordinary materials as well as for metamaterials with negative material constants.

  1. Prevalence of caries in Brazilian children with cleft lip and∕or palate, aged 6 to 36 months

    Directory of Open Access Journals (Sweden)

    Agda Maria de Moura

    2013-09-01

    Full Text Available The aim of this study was to assess the prevalence of caries in children with cleft lip and∕or palate aged 6–36 months of life. This study was conducted at the University of São Paulo School of Dentistry, Brazil. A total of 143 children were selected (73 male, 70 female, all of whom had at least two erupted teeth. The children were distributed as follows: 88 had cleft lip and palate, 35 had cleft palate, 20 had cleft lip. Dental caries disease was diagnosed according to criteria set by the World Health Organization. It was observed that 18.9% of the study children had caries. No correlation between prevalence of caries and gender or type of cleft was observed. Mean dmf-t was 0.47. The prevalence of caries was higher in the upper arch, and the most affected tooth was the central incisor (p = 0.001. Children with cleft lip and∕or palate did not have high caries indices.

  2. High levels of prevalence related to age and body condition: host-parasite interactions in a water frog Pelophylax kl hispanicus

    Directory of Open Access Journals (Sweden)

    Mar Comas

    2014-06-01

    Full Text Available Host traits can significantly influence patterns of infection and disease. Here, we studied the helminths parasitizing the Italian edible frog Pelophylax kl. hispanicus, giving special attention to the relationship between parasites and host traits such as sex, snout vent length, weight and body condition. The helminth community was composed of seven species: three trematode species (Diplodiscus subclavatus, Gorgodera cygnoides, Pleurogenes claviger, three nematode species (Icosiella neglecta, Oswaldocruzia filiformis, Rhabdias sp. and one acanthocephalan species (Pomphorhychus laevis. We found that prevalence was positively correlated with snout-vent length and weight, but did not differ with body condition or sex. We found that prevalence and mean species richness increased with age. Our results show that abundance of Icosiella neglecta was positively correlated with higher values for host body condition. In fact, we found that high prevalence and mean species richness do not necessarily imply poorer body condition in the parasitized host. In conclusion, our results show that the helminth community in this taxon has great diversity, and this host-parasite system seems to be evolved to low levels of virulence, helminths maintaining a commensal relationship with this frog.

  3. Using a Herd Profile to Determine Age-Specific Prevalence of Bovine Leukemia Virus in Michigan Dairy Herds

    Directory of Open Access Journals (Sweden)

    Ronald J. Erskine

    2012-01-01

    Full Text Available Enzootic bovine leukosis is a contagious disease of cattle caused by the retrovirus, bovine leukemia virus (BLV and is the most common cause of malignant neoplasm in cattle. In order to facilitate surveillance of this disease in dairy herds, we developed a method to combine ELISA of milk collected during routine production testing with a prescribed sampling of cows that is independent of the proportion of cows within each lactation. In 113 Michigan dairy herds, milk samples from ten cows in each of the 1st, 2nd, 3rd, and ≥4th lactations were analyzed for anti-Bovine Leukemia Virus (BLV antibodies by milk ELISA. For each herd, a BLV herd profile (BHP was calculated as the simple average of the percent of BLV-positive cows within each of the four lactation groups. The mean BHP for all herds was 32.8%, with means of 18.5, 28.8, 39.2, and 44.8% of 1st, 2nd, 3rd, and ≥4th lactation animals infected, respectively. In eight herds, we determined the correlation between the BHP, and true herd prevalence by testing the entire lactating herd (r=0.988,  P<0.0001. The BHP allows discrimination of lactation-specific BLV prevalence within a dairy herd, to help identify risk factors and management plans that may be important in transmission of BLV.

  4. High prevalence of vitamin D insufficiency and its association with BMI-for-age among primary school children in Kuala Lumpur, Malaysia

    Directory of Open Access Journals (Sweden)

    Arumugam Mohan

    2011-02-01

    Full Text Available Abstract Background Deficiencies of micronutrients can affect the growth and development of children. There is increasing evidence of vitamin D deficiency world-wide resulting in nutritional rickets in children and osteoporosis in adulthood. Data on the micronutrient status of children in Malaysia is limited. The aim of this study was to determine the anthropometric and micronutrient status of primary school children in the capital city of Kuala Lumpur. Methods A cross sectional study of primary aged school children was undertaken in 2008. A total of 402 boys and girls aged 7-12 years, attending primary schools in Kuala Lumpur participated in the study. Fasting blood samples were taken to assess vitamin D [as 25(OHD], vitamin B12, folate, zinc, iron, and ferritin and haemoglobin concentrations. Height-for-age and body mass index for age (BMI-for-age of the children were computed. Results Most of the children had normal height-for-age (96.5% while slightly over half (58.0% had normal BMI-for-age. A total of 17.9% were overweight and 16.4% obese. Prevalence of obesity was significantly higher among the boys (25% than in the girls (9.5% (χ2 = 22.949; P 12. In contrast, 35.3% of the children had serum 25(OHD concentrations indicative of vitamin D deficiency(≤37.5 nmol/L and a further 37.1% had insufficiency concentrations (> 37.5-≤50 nmol/L. Among the boys, a significant inverse association was found between serum vitamin D status and BMI-for-age (χ2 = 5.958; P = .016. Conclusions This study highlights the presence of a high prevalence of sub-optimal vitamin D status among urban primary school children in a tropical country. In light of the growing problem of obesity in Malaysian children, these findings emphasize the important need for appropriate interventions to address both problems of obesity and poor vitamin D status in children.

  5. Competing risks and time-dependent covariates

    DEFF Research Database (Denmark)

    Cortese, Giuliana; Andersen, Per K

    2010-01-01

    Time-dependent covariates are frequently encountered in regression analysis for event history data and competing risks. They are often essential predictors, which cannot be substituted by time-fixed covariates. This study briefly recalls the different types of time-dependent covariates...

  6. Covariant Quantization of D-branes

    OpenAIRE

    Kallosh, Renata

    1997-01-01

    We have found that kappa-symmetry allows a covariant quantization provided the ground state of the theory is strictly massive. For D-p-branes a Hamiltonian analysis is performed to explain the existence of a manifestly supersymmetric and Lorentz covariant description of the BPS states of the theory. The covariant quantization of the D-0-brane is presented as an example.

  7. Seasonality and shift in age-specific malaria prevalence and incidence in Binko and Carrière villages close to the lake in Selingué, Mali

    DEFF Research Database (Denmark)

    Touré, Mahamoudou; Sanogo, Daouda; Dembele, Soumaila;

    2016-01-01

    BACKGROUND: Malaria transmission in Mali is seasonal and peaks at the end of the rainy season in October. This study assessed the seasonal variations in the epidemiology of malaria among children under 10 years of age living in two villages in Selingué: Carrière, located along the Sankarani River...... but distant from the hydroelectric dam, and Binko, near irrigated rice fields, close to the dam. The aim of this study was to provide baseline data, seasonal pattern and age distribution of malaria incidence in two sites situated close to a lake in Selingué. METHODS: Geographically, Selingué area is located...... in the basin of Sakanrani and belongs to the district of Yanfolila in the third administrative region of Mali, Sikasso. Two cross-sectional surveys were conducted in October 2010 (end of transmission season) and in July 2011 (beginning of transmission season) to determine the point prevalence of asymptomatic...

  8. Prevalence and risk factors of poor sleep quality among Chinese elderly in an urban community: results from the Shanghai aging study.

    Directory of Open Access Journals (Sweden)

    Jianfeng Luo

    Full Text Available BACKGROUND: Sleep disorders causes a significant negative effect on mental and physical health, particularly among the elderly. The disease burden and risk factors of poor sleep quality of the elderly need to be verified using a validated form of measurement in urban mainland China. METHODS: This study included 1086 community residents aged ≥ 60 years who completed the Chinese version of the Pittsburgh Sleep Quality Index (CPSQI. Poor sleeper was defined by a CPSQI global score of >5. Subjects also accepted the neurological and neuropsychological assessments, including the Mini-Mental State Examination, Center for Epidemiological Studies Depression Scale, and Zung Self-Rating Anxiety Scale (ZSAS. A history of chronic diseases was confirmed by the medical records of each participant. RESULTS: The prevalence of poor sleep quality in this population was 41.5% (95% confidence interval (CI = 38.6-44.5%, with a higher rate observed in elderly females (45.8% [95% CI = 41.9-49.7%] than that in elderly males (35.8% [95% CI = 31.4-40.1%]. The prevalence rate increased with age, from 32.1% (95% CI = 27.8-36.4% in those aged 60-69 years to 52.5% (95% CI = 45.9-59.1% in those aged ≥ 80 years (p value for trend<0.001. Multivariate logistic regression analysis indicated that age (OR = 1.03[95% CI = 1.01-1.05], p<0.001, less education duration (OR = 1.04 [95% CI = 1.01-1.08, p = 0.014, living alone (OR = 1.62 [95% CI = 1.02-2.58], p = 0.04, anxiety (ZSAS score: OR = 1.09 [95% CI = 1.05-1.12], p<0.001, number of chronic disease (OR = 1.18 [95% CI = 1.07-1.30], p = 0.14 and arthritis (OR = 1.45[95% CI = 1.05-2.01], p = 0.025 were risk factors of poor sleep quality. CONCLUSIONS: Poor sleep quality is highly prevalent among elderly Chinese residents in urban Shanghai. Growing attention and comprehensive countermeasures involving psycho-social and personal activities might alleviate the sleep problem in the elderly.

  9. Prevalence and associated factors of myopia among primary and middle school-aged students: a school-based study in Guangzhou.

    Science.gov (United States)

    Guo, L; Yang, J; Mai, J; Du, X; Guo, Y; Li, P; Yue, Y; Tang, D; Lu, C; Zhang, W-H

    2016-06-01

    PurposeTo estimate the prevalence of myopia among primary and middle school-aged students in Guangzhou and to explore the potentially contributing factors to myopia.MethodsThis cross-sectional study was based on a sample of students in grades 1-6 and grades 7-9. Data were collected from refractive error measurements and a structured questionnaire.ResultsA total of 3055 participants were involved in this analysis, and the overall prevalence of myopia was 47.4% (95% confidence interval (CI)= 45.6-49.2%). The prevalence of myopia in students increased along with the growth of grade level; the prevalence of myopia in students in grade 1 was only 0.2%, as it increased to 38.8% in students in grade 3, and the rate was the highest (68.4%) in students in grade 9. Girls were at a higher risk of myopia than boys (adjusted odds ratio=1.22, 95% CI=1.04-1.44). Both male and female students whose distance of reading was longer than 25 cm were less likely to have myopia and who have one or two myopic parents were at a higher risk of myopia. In addition, reading for pleasure more than 2 h per day (adjusted odds ratio=1.84, 95% CI=1.09-3.12) was only positively associated with myopia in boys and spending time watching television per week was only positively associated with myopia in girls.ConclusionMyopia in students is a significant public health problem in Guangzhou. Female gender, higher grade, longer time spent for near work, shorter distance of near work, and parental myopia were shown to be associated with the increasing risk of myopia in children. PMID:26965016

  10. Prevalence and associated factors of myopia among primary and middle school-aged students: a school-based study in Guangzhou.

    Science.gov (United States)

    Guo, L; Yang, J; Mai, J; Du, X; Guo, Y; Li, P; Yue, Y; Tang, D; Lu, C; Zhang, W-H

    2016-06-01

    PurposeTo estimate the prevalence of myopia among primary and middle school-aged students in Guangzhou and to explore the potentially contributing factors to myopia.MethodsThis cross-sectional study was based on a sample of students in grades 1-6 and grades 7-9. Data were collected from refractive error measurements and a structured questionnaire.ResultsA total of 3055 participants were involved in this analysis, and the overall prevalence of myopia was 47.4% (95% confidence interval (CI)= 45.6-49.2%). The prevalence of myopia in students increased along with the growth of grade level; the prevalence of myopia in students in grade 1 was only 0.2%, as it increased to 38.8% in students in grade 3, and the rate was the highest (68.4%) in students in grade 9. Girls were at a higher risk of myopia than boys (adjusted odds ratio=1.22, 95% CI=1.04-1.44). Both male and female students whose distance of reading was longer than 25 cm were less likely to have myopia and who have one or two myopic parents were at a higher risk of myopia. In addition, reading for pleasure more than 2 h per day (adjusted odds ratio=1.84, 95% CI=1.09-3.12) was only positively associated with myopia in boys and spending time watching television per week was only positively associated with myopia in girls.ConclusionMyopia in students is a significant public health problem in Guangzhou. Female gender, higher grade, longer time spent for near work, shorter distance of near work, and parental myopia were shown to be associated with the increasing risk of myopia in children.

  11. Suicidal ideation in adolescents aged 11 to 15 years: prevalence and associated factors Ideação suicida em adolescentes de 11 a 15 anos: prevalência e fatores associados

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    Luciano Dias de Mattos Souza

    2010-03-01

    Full Text Available OBJECTIVE: To verify the prevalence and associated factors of suicidal ideation among adolescents aged 11 to 15 years. METHOD: Cross-sectional population-based study. Adolescents completed a self-report that contained the Children's Depression Inventory. Suicidal ideation was measured according to item 9 of the Children's Depression Inventory. Multivariate logistic regression analysis was applied using a hierarchical model. RESULTS: 1145 adolescents were invited to participate, and 1039 were interviewed (refusal rate: 9.26%. The prevalence of suicidal ideation was 14.1%. Factors associated to suicidal ideation: female gender, current alcohol consumption, use of illicit drugs, symptoms indicating conduct disorders and high Children's Depression Inventory scores for depressive symptoms. CONCLUSION: Prevention strategies should focus on female adolescents, especially those sexually active with probable mental health problems and substance use.OBJETIVO: Verificar a prevalência e fatores associados à ideação suicida entre adolescentes de 11 a 15 anos. MÉTODO: Estudo transversal de base-populacional. Os adolescentes responderam a um questionário auto-aplicável que continha o Children's Depression Inventory. A ideação suicida foi mensurada de acordo com o item 9 do Children's Depression Inventory. Foi utilizada a análise de regressão logística multivariada acompanhada de um modelo hierárquico. RESULTADOS: 1.145 adolescentes foram convidados a participar e 1.039 foram entrevistados (recusas: 9,26%. A prevalência de ideação suicida foi de 14,1%. Fatores associados à ideação suicida: sexo feminino, consumir álcool, uso de drogas ilícitas, apresentar sintomas indicativos de transtorno de conduta e elevada pontuação no Children's Depression Inventory para sintomas depressivos. CONCLUSÃO: Estratégias de prevenção devem priorizar adolescentes do sexo feminino, principalmente aquelas sexualmente ativas, com prováveis problemas de sa

  12. Prevalence and Associated Factors of Secondhand Smoke Exposure among Internal Chinese Migrant Women of Reproductive Age: Evidence from China’s Labor-Force Dynamic Survey

    Science.gov (United States)

    Gong, Xiao; Luo, Xiaofeng; Ling, Li

    2016-01-01

    Secondhand smoke (SHS) is a major risk factor for poor health outcomes among women in China, where proportionately few women smoke. This is especially the case as it pertains to women’s reproductive health, specifically migrant women who are exposed to SHS more than the population at large. There are several factors which may increase migrant women’s risk of SHS exposure. This paper aims to investigate the prevalence and associated factors of SHS exposure among internal Chinese migrant women of reproductive age. The data used were derived from the 2014 Chinese Labor Dynamic Survey, a national representative panel survey. The age-adjusted rate of SHS exposure of women of reproductive age with migration experience was of 43.46% (95% CI: 40.73%–46.40%), higher than those without migration experience (35.28% (95% CI: 33.66%–36.97%)). Multivariate analysis showed that participants with a marital status of “Widowed” had statistically lower exposure rates, while those with a status of “Cohabitation” had statistically higher exposure. Those with an undergraduate degree or above had statistically lower SHS exposure. Those with increasing levels of social support, and those who currently smoke or drink alcohol, had statistically higher SHS exposure. Participants’ different work-places had an effect on their SHS exposure, with outdoor workers statistically more exposed. Our findings suggest that urgent tobacco control measures should be taken to reduce smoking prevalence and SHS exposure. Specific attention should be paid to protecting migrant women of reproductive age from SHS. PMID:27043604

  13. Association of socio-economic features, hygienic status, age group and gender with prevalence of waterborne diseases in rawalpindi and islamabad

    International Nuclear Information System (INIS)

    Prevention of waterborne illness is of great concern all over the world. Waterborne diseases represent significant burden of diseases in the globe. Nearly 4% of diseases are attributable to water, sanitation and hygiene, and approximately 2.2 million people die every year due to diarrheal diseases worldwide. This study was carried out to find association of socio-economic features, hygienic status, age groups and gender with prevalence of water borne diseases in Rawalpindi and Islamabad. A research questionnaire was designed with questions related to demographic data, drinking water data and prevalence of water borne disease. The research questionnaire was interviewed to different respondents above 18 years of age randomly selected from different settings of Rawalpindi and Islamabad belonging to different socio-economic statuses. Data was analysed by employing cross tabulation and chi-square test with help of statistical software. The more frequent age group (47%) was 30 to 45 years. Proportion of diarrhea in females and males of middle age group were calculated as 36.11 % and 11.11 %, respectively. The second more frequent reported disease was jaundice with 15.9% of the target population being males and 16.7% females. Diarrhea was observed to be the major waterborne disease constituting 41 % of the population with poor hygiene practices. The hygienic practices were significantly associated with waterborne diseases (P = <0.001). Waterborne diseases were also, associated with financial status (P=0.02) and literacy rate (p=0.03). The current study concludes that improvement in the hygienic conditions and hygienic practices will playa pivotal role to prevent faeco-oral infections and reduce the waterborne disease burden. In targeted areas due to poor economic conditions, the population failed to achieve better hygienic practices and therefore there is a need to strengthen water filtration system and awareness of hygienic routine practices in these areas. (author)

  14. the potential of AGE MODE, an age-dependent model, to estimate usual intakes and prevalences of inadequate intakes in a population.

    NARCIS (Netherlands)

    Waijers, Patricia M C M; Dekkers, Arnold L M; Boer, Jolanda M A; Boshuizen, Hendriek C; Rossum, Caroline T M van

    2006-01-01

    Dietary intake data often stem from short-term measurements. However, for dietary assessment, generally the habitual intake distribution is of interest. Currently, habitual intake distributions are often estimated separately for subgroups of gender and age and do not take into account the variation

  15. Patterns of pulmonary perfusion scans in normal subjects. IV. The prevalence of abnormal scans in smokers 30 to 49 years of age

    International Nuclear Information System (INIS)

    The usefulness of ventilation-perfusion scans in the diagnosis of pulmonary embolism is limited by the wide range of pulmonary diseases that are associated with abnormal scans, and by the largely undetermined prevalence of abnormal scans in persons without cardiopulmonary disease. In prior studies, we found perfusion defects to be rarely present in young persons and in older nonsmokers. To determine if normal older smokers have a higher prevalence of abnormal ventilation and perfusion scans, we performed six-view /sup 99m/Tc perfusion (Q) scans and 133Xe ventilation (V) scans in 40 subjects 30 to 49 yr of age who had no known cardiopulmonary disease. Each subject had undergone a history, physical examination, electrocardiogram, spirometry, and posteroanterior chest roentgenogram prior to scanning. All V and Q scans were interpreted blindly and independently by two experienced readers. No subject demonstrated a lobar or segmental defect on two views. One subject had a matched subsegmental defect, and one subject had delayed washout from a subsegmental area of the right upper lobe during V scanning, with a normal Q scan. We conclude that abnormal V and Q scans are uncommon among normal smokers 30 to 49 yr of age

  16. Legionella pneumophila in bronchoalveolar lavage samples of patients suffering from severe respiratory infections: Role of age, sex and history of smoking in the prevalence of bacterium

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    Faradonbeh Fatemeh Alaei

    2015-01-01

    Full Text Available Introduction. Legionella pneumophila is the most commonly detected cause of legionellosis, which is an acute respiratory tract infection with high morbidity and mortality rates. Objective. The aim of this study was to investigate the prevalence rate of L. pneumophila in bronchoalveolar lavages and study the role of sex, age and history of smoking as risk factors for susceptibility to the bacterium. Methods. One hundred bronchoalveolar lavage samples were collected from the Iranian health centers and immediately transferred to laboratory. The samples were cultured and those that were L. pneumophila positive were subjected to PCR method with respect to the 16S rRNA gene. Results. Twelve out of 100 samples were positive for L. pneumophila (12%. Patients older than 70 years had the highest incidence of L. pneumophila (17.77%. Prevalence of L. pneumophila in male and female patients was 14.81% and 8.69%, respectively. Total incidence of L. pneumophila in patients with and without history of smoking was 18% and 6%, respectively. There were significant differences in the incidence of bacterium between groups of our study. Conclusion. Sex, age and history of smoking are predominant risk factors for the occurrence of L. pneumophila. However, more studies should be undertaken to confirm these results.

  17. Prevalence of clinical anxiety, clinical depression and associated risk factors in chinese young and middle-aged patients with osteonecrosis of the femoral head.

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    Sheng-Bao Chen

    Full Text Available To investigate the prevalence of clinical anxiety and clinical depression in Chinese young and mid-aged patients with osteonecrosis of the femoral head (ONFH and to analyze their potential risk factors.Two hundred and sixteen Chinese patients with ONFH were consecutively enrolled in this cross-sectional study from January 2010 to December 2010. The Zung self-rating anxiety scale (SAS and the Zung self-rating depression scale (SDS were used to assess the prevalence of clinical anxiety and clinical depression. An additional questionnaire containing seventeen items of potential risk factors was completed by all patients. Binary logistic regression analysis was employed to reveal potential risk factors of anxiety and depression.The prevalence of clinical anxiety and clinical depression was 20.4% and 21.8% in Chinese young and middle-aged patients with ONFH, respectively. Binary regression analysis showed that independent risk factors correlated with high incidence of clinical anxiety included involved femoral head (OR = 3.168, 95% CI: 1.496 - 6.708 and stages of ONFH (ORIV-V / II = 5.383, 95% CI: 1.664-17.416. Independent risk factors correlated with high incidence of depression included gender (OR = 2.853, 95% CI: 1.467-5.778, comorbid diseases (OR = 4.243, 95% CI: 1.940-9.278 and stages of the disease (OR IV-V/II = 16.963, 95% CI: 4.404-65.331.Patients with bilateral ONFH are inclined to have clinical anxiety, while female patients and patients with comorbid diseases might tend to get clinical depression. Advanced stages of ONFH are independent risk factors for both clinical anxiety and clinical depression.

  18. Covariance Evaluation Methodology for Neutron Cross Sections

    Energy Technology Data Exchange (ETDEWEB)

    Herman,M.; Arcilla, R.; Mattoon, C.M.; Mughabghab, S.F.; Oblozinsky, P.; Pigni, M.; Pritychenko, b.; Songzoni, A.A.

    2008-09-01

    We present the NNDC-BNL methodology for estimating neutron cross section covariances in thermal, resolved resonance, unresolved resonance and fast neutron regions. The three key elements of the methodology are Atlas of Neutron Resonances, nuclear reaction code EMPIRE, and the Bayesian code implementing Kalman filter concept. The covariance data processing, visualization and distribution capabilities are integral components of the NNDC methodology. We illustrate its application on examples including relatively detailed evaluation of covariances for two individual nuclei and massive production of simple covariance estimates for 307 materials. Certain peculiarities regarding evaluation of covariances for resolved resonances and the consistency between resonance parameter uncertainties and thermal cross section uncertainties are also discussed.

  19. Study on the prevalence and the age at initial colonization of campylobacter in broiler flocks in central province of Sri Lanka

    International Nuclear Information System (INIS)

    Campylobacter is considered one of the main causes of bacterial enteritis worldwide and poultry meat appears to act as a common source of infection (Vandeplas et al., 2008). In Sri Lanka, the available data to show the importance of campylobacter as a cause of diarrhoeal diseases is sparse and the involvement of poultry in relation to Campylobacter has not been identified. Therefore this study was carried out to investigate the association of campylobacter with broiler chicken. The Campylobacter isolation and identification procedure based on ISO standard was established and poultry meat samples collected from retail markets were tested. A considerable number of meat samples were contaminated with thermotolerant Campylobacter. As Campylobacter is a commensal in the chicken gut, though it is a pathogen to human, the prevalence of Campylobacter in broiler flocks was studied. Cloacal swabs collected at farms and caeca collected at slaughter in processing plants were analysed. Out of 59 samples collected from the Central Province 42 became positive for Campylobacter. The prevalence of Campylobacter in broiler flocks is 71%. High prevalence indicated the importance of controlling the pathogen but there was no data available on the ecology of the pathogen in Sri Lanka. Previous studies elsewhere have shown that factors like geographical location, seasonality, farming system, bio-security measures as the key factors influencing the host pathogen relationship. However, most data have been generated in nontropical countries with clear summer and winter seasons (Newell and Fearnley, 2003). The relative importance of these factors in Sri Lanka was questionable as it is a tropical country with no clear seasonality. To investigate the colonization of Campylobacter in broiler flocks twenty broiler flocks reared in two farms where different management practices in use, in the Central Province were monitored during one year. From each flock, cloacae swabs were collected from

  20. Prevalence of at-risk genotypes for genotoxic effects decreases with age in a randomly selected population in Flanders: a cross sectional study

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    van Delft Joost HM

    2011-10-01

    Full Text Available Abstract Background We hypothesized that in Flanders (Belgium, the prevalence of at-risk genotypes for genotoxic effects decreases with age due to morbidity and mortality resulting from chronic diseases. Rather than polymorphisms in single genes, the interaction of multiple genetic polymorphisms in low penetrance genes involved in genotoxic effects might be of relevance. Methods Genotyping was performed on 399 randomly selected adults (aged 50-65 and on 442 randomly selected adolescents. Based on their involvement in processes relevant to genotoxicity, 28 low penetrance polymorphisms affecting the phenotype in 19 genes were selected (xenobiotic metabolism, oxidative stress defense and DNA repair, respectively 13, 6 and 9 polymorphisms. Polymorphisms which, based on available literature, could not clearly be categorized a priori as leading to an 'increased risk' or a 'protective effect' were excluded. Results The mean number of risk alleles for all investigated polymorphisms was found to be lower in the 'elderly' (17.0 ± 2.9 than the 'adolescent' (17.6 ± 3.1 subpopulation (P = 0.002. These results were not affected by gender nor smoking. The prevalence of a high (> 17 = median number of risk alleles was less frequent in the 'elderly' (40.6% than the 'adolescent' (51.4% subpopulation (P = 0.002. In particular for phase II enzymes, the mean number of risk alleles was lower in the 'elderly' (4.3 ± 1.6 than the 'adolescent' age group (4.8 ± 1.9 P 4 = median number of risk alleles was less frequent in the 'elderly' (41.3% than the adolescent subpopulation (56.3%, P 8 = median number of risk alleles for DNA repair enzyme-coding genes was lower in the 'elderly' (37,3% than the 'adolescent' subpopulation (45.6%, P = 0.017. Conclusions These observations are consistent with the hypothesis that, in Flanders, the prevalence of at-risk alleles in genes involved in genotoxic effects decreases with age, suggesting that persons carrying a higher number of

  1. Prevalence of Tobacco Use among Students Aged 13-15 Years in the South-Eastern Europe Health Network

    Science.gov (United States)

    Stojiljkovic, Djorde; Haralanova, Maria; Nikogosian, Haik; Petrea, Ionela; Chauvin, James; Warren, Charles W.; Jones, Nathan R.; Asma, Samira

    2008-01-01

    Objective: To examine adolescent tobacco use among members of the South-Eastern Europe (SEE) Health Network using data from the Global Youth Tobacco Survey (GYTS). Methods: Nationally representative samples were drawn from students in grades associated with youth aged 13 to 15 in Albania, Bosnia and Herzegovina, Bulgaria, Croatia, the Former…

  2. The causes of variation in the presence of genetic covariance between sexual traits and preferences.

    Science.gov (United States)

    Fowler-Finn, Kasey D; Rodríguez, Rafael L

    2016-05-01

    Mating traits and mate preferences often show patterns of tight correspondence across populations and species. These patterns of apparent coevolution may result from a genetic association between traits and preferences (i.e. trait-preference genetic covariance). We review the literature on trait-preference covariance to determine its prevalence and potential biological relevance. Of the 43 studies we identified, a surprising 63% detected covariance. We test multiple hypotheses for factors that may influence the likelihood of detecting this covariance. The main predictor was the presence of genetic variation in mate preferences, which is one of the three main conditions required for the establishment of covariance. In fact, 89% of the nine studies where heritability of preference was high detected covariance. Variables pertaining to the experimental methods and type of traits involved in different studies did not greatly influence the detection of trait-preference covariance. Trait-preference genetic covariance appears to be widespread and therefore represents an important and currently underappreciated factor in the coevolution of traits and preferences.

  3. Higher prevalence of X-ray selected AGN in intermediate-age galaxies up to z ˜ 1

    Science.gov (United States)

    Hernán-Caballero, Antonio; Alonso-Herrero, Almudena; Pérez-González, Pablo G.; Barro, Guillermo; Aird, James; Ferreras, Ignacio; Cava, Antonio; Cardiel, Nicolás; Esquej, Pilar; Gallego, Jesús; Nandra, Kirpal; Rodríguez-Zaurín, Javier

    2014-10-01

    We analyse the stellar populations in the host galaxies of 53 X-ray selected optically dull active galactic nuclei (AGN) at 0.34 SHARDS). The spectral resolution of SHARDS allows us to consistently measure the strength of the 4000 Å break, Dn(4000), a reliable age indicator for stellar populations. We confirm that most X-ray selected moderate-luminosity AGN (LX 1010.5 M⊙) and that the observed fraction of galaxies hosting an AGN increases with the stellar mass. A careful selection of random control samples of inactive galaxies allows us to remove the stellar mass and redshift dependences of the AGN fraction to explore trends with several stellar age indicators. We find no significant differences in the distribution of the rest-frame U - V colour for AGN hosts and inactive galaxies, in agreement with previous results. However, we find significantly shallower 4000 Å breaks in AGN hosts, indicative of younger stellar populations. With the help of a model-independent determination of the extinction, we obtain extinction-corrected U - V colours and light-weighted average stellar ages. We find that AGN hosts have younger stellar populations and higher extinction compared to inactive galaxies with the same stellar mass and at the same redshift. We find a highly significant excess of AGN hosts with Dn(4000) ˜ 1.4 and light-weighted average stellar ages of 300-500 Myr, as well as a deficit of AGN in intrinsic red galaxies. We interpret failure in recognizing these trends in previous studies as a consequence of the balancing effect in observed colours of the age-extinction degeneracy.

  4. Epidemiology of severe acute respiratory illness (SARI among adults and children aged ≥5 years in a high HIV-prevalence setting, 2009-2012.

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    Cheryl Cohen

    Full Text Available There are few published studies describing severe acute respiratory illness (SARI epidemiology amongst older children and adults from high HIV-prevalence settings. We aimed to describe SARI epidemiology amongst individuals aged ≥5 years in South Africa.We conducted prospective surveillance for individuals with SARI from 2009-2012. Using polymerase chain reaction, respiratory samples were tested for ten viruses, and blood for pneumococcal DNA. Cumulative annual SARI incidence was estimated at one site with population denominators.We enrolled 7193 individuals, 9% (621/7067 tested positive for influenza and 9% (600/6519 for pneumococcus. HIV-prevalence was 74% (4663/6334. Among HIV-infected individuals with available data, 41% of 2629 were receiving antiretroviral therapy (ART. The annual SARI hospitalisation incidence ranged from 325-617/100,000 population. HIV-infected individuals experienced a 13-19 times greater SARI incidence than HIV-uninfected individuals (p7 days rather than <2 days (OR1.7; 95%CI:1.2-2.2 and had a higher case-fatality ratio (8% vs 5%;OR1.7; 95%CI:1.2-2.3, but were less likely to be infected with influenza (OR 0.6; 95%CI:0.5-0.8. On multivariable analysis, independent risk indicators associated with death included HIV infection (OR 1.8;95%CI:1.3-2.4, increasing age-group, receiving mechanical ventilation (OR 6.5; 95%CI:1.3-32.0 and supplemental-oxygen therapy (OR 2.6; 95%CI:2.1-3.2.The burden of hospitalized SARI amongst individuals aged ≥5 years is high in South Africa. HIV-infected individuals are the most important risk group for SARI hospitalization and mortality in this setting.

  5. The prevalence and the socio – economic costs of smoking among the working age population in Latvia

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    Kokarevica A.

    2016-01-01

    Full Text Available Smoking is a health problem, the costs of which include sickness, pain, grief and misery. But tobacco use also imposes a significant economic burden on society. One efficient way to assess the adverse health effects of smoking on a society is to translate smoking-caused illnesses, premature mortality, and productivity losses into economic terms, a universal marker for measuring the adverse effects of smoking. Due to the high proportion of smokers, Latvia faces high male mortality from smoking-related diseases; life expectancy for men in the age group 35–64 years is 2.44 years less than for non-smokers in the same age group, losing 37% of total lost years of life and therefore the government loses approximately 45 88346 Euro per year from YPLL from smoking related diseases.

  6. High prevalence of anti-D antibodies among women of childbearing age at Centre Pasteur of Cameroon.

    OpenAIRE

    Belinga, Suzanne,; Ngo Sack, Françoise; Bilong, Catherine; Manga, Jeanne; Mengue, Marie-Ange; Tchendjou, Patrice,

    2009-01-01

    International audience We conducted a cross sectional retrospective study to determine anti-D and D-negative phenotype rates among Cameroonian women of reproductive age (15-44 years), in order to evaluate the importance of D alloimmunization. Analysis of the haematology laboratory records from January 2006 to December 2007 harvested 225 results for red blood cell alloantibody screening and 2460 D phenotypes. Anti-D rate was found to be high at 4% and not linked to women's parity. Three hun...

  7. Prevalence of anemia in children 1 to 12 years of age. Results from a nationwide probabilistic survey in Mexico

    OpenAIRE

    Salvador Villalpando; Teresa Shamah; Claudia Ivonne Ramírez; Fabiola Mejía; Rivera, Juan A.

    2003-01-01

    Objective. To describe the epidemiology and analyze factors associated with iron deficiency anemia in a probabilistic sample of the Encuesta Nacional de Nutrición 1999 (ENN- 99) [National Nutritional Survey 1999 (NNS-99)]. Material and Methods. The sample included 8 111 children aged 1 to 12 years, and was nationaly representative by rural and urban strata and by four geographical regions. Capillary hemoglobin was measured using a portable photometer (HemoCue). The analysis of the determining...

  8. Prevalence of anemia in children 1 to 12 years of age: results from a nationwide probabilistic survey in Mexico

    OpenAIRE

    Villalpando Salvador; Shamah-Levy Teresa; Ramírez-Silva Claudia Ivonne; Mejía-Rodríguez Fabiola; Rivera Juan A

    2003-01-01

    OBJECTIVE: To describe the epidemiology and analyze factors associated with iron deficiency anemia in a probabilistic sample of the Encuesta Nacional de Nutrición 1999 (ENN-99) [National Nutritional Survey 1999 (NNS-99)]. MATERIAL AND METHODS: The sample included 8 111 children aged 1 to 12 years, and was nationaly representative by rural and urban strata and by four geographical regions. Capillary hemoglobin was measured using a portable photometer (HemoCue). The analysis of the determining ...

  9. Prevalence of the acetabular sublabral sulcus at MR arthrography in patients under 17 years of age: does it exist?

    Energy Technology Data Exchange (ETDEWEB)

    Magerkurth, Olaf [University of Michigan, Department of Radiology, Ann Arbor, MI (United States); Hospital Baden, Department of Radiology, Baden (Switzerland); Jacobson, Jon A.; Morag, Yoav; Fessell, David [University of Michigan, Department of Radiology, Ann Arbor, MI (United States); Bedi, Asheesh; Sekiya, Jon K. [University of Michigan, Department of Orthopedic Surgery, Ann Arbor, MI (United States)

    2015-04-18

    To retrospectively determine characteristics of contrast-filled acetabular labral clefts in patients under the age of 17 years at MR arthrography (Mra) correlated with arthroscopy, which may impact the thinking regarding the existence of a sublabral sulcus. After IRB approval, 41 patients under the age of 17 who had MRa were identified. The following observations of contrast-filled clefts were assessed: (1) presence/absence, (2) location, (3) depth, (4) abnormal signal within the labrum and (5) shape (linear, gaping, complex). Fisher's exact and the Wilcoxon matched-pairs signed-rank test were performed. Interreader agreement was calculated with Cohen's k. Reader 1 found clefts in 41 %. Depth was less than half in 6 %, more than half in 65 % and full thickness in 29 %. Shape was linear in 53 %, gaping in 18 % and complex in 29 %. Signal changes occurred in 88 %. Reader 2 found clefts in 29 %. Depth was less than half in 17 %, more than half in 58 % and full thickness in 25 %. Shape was linear in 50 %, gaping in 42 % and complex in 17 %. Signal changes occurred in 50 %. None of the clefts fulfilled the criteria for a sublabral sulcus at MRa and arthroscopy. None of the clefts found in our subjects under the age of 17 years met the MRa and arthroscopy criteria for a sublabral sulcus, which supports the theory that such clefts represent labral tears. (orig.)

  10. Prevalência de dilatação da aorta abdominal em coronariopatas idosos Prevalence of abdominal aortic dilatation in patients aged 60 years or older with coronary disease

    Directory of Open Access Journals (Sweden)

    Guilherme Vieira Meirelles

    2007-06-01

    Full Text Available CONTEXTO: A realização de programas de triagem para o aneurisma da aorta abdominal de forma indiscriminada auxiliará uma pequena porcentagem de indivíduos, mas ao considerarmos grupos com fatores de risco relacionados à dilatação da aorta, aumentando a probabilidade da doença, este permitirá um direcionamento adequado dos recursos e um benefício maior à população. Programas direcionados pelas sociedades médicas, permitindo um diagnóstico precoce das doenças vasculares e conseqüentemente um melhor preparo do doente, promoveriam melhores taxas de sobrevida com menor morbidade. OBJETIVO: Avaliar a prevalência da dilatação da aorta abdominal em uma amostra de pacientes idosos com mais de 60 anos de idade, portadores de coronariopatia aterosclerótica diagnosticada por cineangiocoronariografia. MÉTODOS: Para a seleção dessa amostra, levou-se em consideração o fato de que a avaliação pré-operatória de cirurgia vascular não tenhasido a indicação do cateterismo. Procedeu-se então a avaliação, baseada na anamnese, exame físico e Doppler ultra-som da aorta abdominal. A análise estatística iniciou-se com o teste qui-quadrado, com a posterior análise de regressão logística multivariada e regressão logística univariada, considerando significativo um p BACKGROUND: Indiscriminate screening programs for abdominal aortic aneurysm will help a small percentage of individuals. However, when considering groups with risk factors associated with aortic dilatation, which increases the probability of the disease, such programs will provide an adequate allocation of resources and a greater benefit to the population. Programs guided by medical societies, providing an early diagnosis of vascular diseases and consequently a better preparation of patients, would result in better survival rates with lower morbidity. OBJECTIVE: To evaluate the prevalence of abdominal aortic dilatation in patients aged 60 years or older with

  11. Prevalence and Predictors of Iron Deficiency Anemia in Children under Five Years of Age in Pakistan, A Secondary Analysis of National Nutrition Survey Data 2011-2012.

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    Muhammad Atif Habib

    Full Text Available Iron deficiency Anemia (IDA in children is a recognized public health problem that impacts adversely on child morbidity, mortality and impairs cognitive development. In Pakistan information on the true prevalence and predictors of IDA is limited. This study sought to investigate IDA in children under five years of age using data from a nationally representative stratified cross-sectional survey.Secondary analysis was performed on the National Nutrition Survey in Pakistan 2011-2012. We used a pre-structured instrument to collect socio demographic and nutritional data on mothers and children. We also collected Anthropometric measurements and blood samples for micronutrient deficiencies. IDA was defined as having both haemoglobin levels of <110 g/L and ferritin levels of < 12 μg/L. Data analysis was performed by applying univariate and multivariate techniques using logistic regression through SPSS.A total of 7138 children aged between 6-59 months were included in the analysis. The prevalence of IDA was 33.2%. In multivariate regression analysis adjusted odds ratios (AOR were calculated. Age < 24 months (AOR 1.40, 95% CI 1.18-1.55 p <0.05, stunting (AOR 1.42 CI 1.23-1.63 p<0.05, presence of clinical anemia (AOR 5.69 CI 4.93-6.56 p<0.05, having a mother with IDA (AOR 1.72 CI 1.47-2.01 p<0.05 and household food insecurity (AOR 1.20 CI 1.10-1.40 P<0.05 were associated with IDA. Living in a rural area (AOR 0.77 CI 0.65-0.90 p<0.05 and being a female child (AOR 0.87 CI 0.76-0.98 p<0.05 were associated with reduced odds of IDA.The prevalence of IDA amongst Pakistani children represents a moderate burden that disproportionately affects the youngest, growth retarded children, affected children are more likely to have mothers with IDA and live in areas where food security is lacking. National efforts to alleviate the burden of IDA should involve both short term vertical programs such as iron supplementation and long term horizontal programs including wheat

  12. PREVALENCE AND RISK FACTORS OF BACTERIAL VAGINOSIS AMONG WOMEN OF REPRODUCTIVE AGE ATTENDING RURAL TERTIARY CARE INSTITUTE OF WESTERN UTTAR PRADESH

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    Amit

    2016-05-01

    Full Text Available BACKGROUND Bacterial vaginosis (BV is the most common cause of abnormal vaginal discharge among women of child bearing age and is associated with adverse obstetric and gynaecologic outcomes. OBJECTIVES The aim of the study was to determine the prevalence of BV by use of Nugent’s criteria and to identify modifiable and nonmodifiable, the risk factors associated with BV in women of reproductive age. METHODOLOGY A descriptive cross sectional study was conducted from January 2013 to December 2013, among women of child bearing age with complaints of vaginal discharge, attending Gynaecology and Obstetric OPD at UPRIMS & R, Saifai, Etawah. Bacterial morphotypes indicative of BV were identified by Nugent’s criteria. A pre-coded questionnaire was used to collect demographic and behavioural characteristics (including contraceptive usage, douching practice in the study participants. DATA ANALYSIS Bivariate and multivariate analyses by logistic regression method performed. Crude Odds ratio and Adjusted Odds Ratio for the association between BV and demographic or behavioural characteristics was calculated using Poisson regression. Sensitivity, specificity, PPV and NPV were calculated keeping Nugent score of 7 for BV as ‘Gold standard.’ RESULTS A prevalence of 31.5.0%, (95% CI 25.6-38.2 was obtained from the study population. Sensitivity, specificity, PPV and NPV of Amsler’s criteria for clinical diagnosis of BV was 67.7%, 89.39%, 74.58% and 85.02% respectively. Low socioeconomic status including occupation, illiteracy, Intrauterine Contraceptive Device (IUCD usage, douching practice and condom usage were significantly associated with BV. CONCLUSIONS The prevalence of BV was 31.5% in this population. Concordance between Amsel’s criteria and Nugent’s was low (67.67%. Among individual Amsel’s parameters, vaginal pH >4.5 had highest sensitivity (84.61% and demonstration of ‘Clue Cell’ was most specific (92.2%. Risk factors for BV ought to

  13. Higher prevalence of X-ray selected AGN in intermediate-age galaxies up to z ~ 1

    OpenAIRE

    Hernán-Caballero, Antonio; Alonso-Herrero, A.; Pérez-González, P. G.; Barro, Guillermo; Aird, James; Ferreras, Ignacio; Cava, A; Esquej, P.; Gallego, Jesús; Nandra, K.; Rodríguez Zaurín, Javier

    2014-01-01

    We analyse the stellar populations in the host galaxies of 53 X-ray selected optically dull active galactic nuclei (AGN) at 0.34 < z < 1.07 with ultradeep (mAB = 26.5, 3σ) optical mediumband (R ~ 50) photometry from the Survey for High-z Absorption Red and Dead Sources (SHARDS). The spectral resolution of SHARDS allows us to consistently measure the strength of the 4000Å break, Dn(4000), a reliable age indicator for stellar populations.We confirm that most X-ray selected moderate-luminosity A...

  14. Group B streptococcus serotype prevalence in reproductive-age women at a tertiary care military medical center relative to global serotype distribution

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    Williams Julie

    2010-11-01

    Full Text Available Abstract Background Group B Streptococcus (GBS serotype (Ia, Ib, II-IX correlates with pathogen virulence and clinical prognosis. Epidemiological studies of seroprevalence are an important metric for determining the proportion of serotypes in a given population. The purpose of this study was to evaluate the prevalence of individual GBS serotypes at Madigan Healthcare System (Madigan, the largest military tertiary healthcare facility in the Pacific Northwestern United States, and to compare seroprevalences with international locations. Methods To determine serotype distribution at Madigan, we obtained GBS isolates from standard-of-care anogenital swabs from 207 women of indeterminate gravidity between ages 18-40 during a five month interval. Serotype was determined using a recently described molecular method of polymerase chain reaction by capsular polysaccharide synthesis (cps genes associated with pathogen virulence. Results Serotypes Ia, III, and V were the most prevalent (28%, 27%, and 17%, respectively. A systematic review of global GBS seroprevalence, meta-analysis, and statistical comparison revealed strikingly similar serodistibution at Madigan relative to civilian-sector populations in Canada and the United States. Serotype Ia was the only serotype consistently higher in North American populations relative to other geographic regions (p Conclusion This study establishes PCR-based serotyping as a viable strategy for GBS epidemiological surveillance. Our results suggest that GBS seroprevalence remains stable in North America over the past two decades.

  15. Population-based prevalence, type- and age-specific distribution of HPV in women before introduction of an HPV-vaccination program in Denmark

    DEFF Research Database (Denmark)

    Kjaer, Susanne K.; Breugelmans, Gabrielle; Munk, Christian;

    2008-01-01

    .2%). Other common HPV types in women with CIN3 included HPV 52, 51, 31, 33 and 18. HPV 16/18 alone was present in 23% of CIN3 lesions and 67% of cervical cancers, and HPV 16/18 together with other high-risk HPV types was present in 41% of CIN3 lesions. This suggests that an efficacious HPV 16/18 vaccine......Knowledge about the prevalence of human papillomavirus (HPV) on a population level is important. We conducted a large population-based study in Denmark to determine the overall and age-specific HPV prevalence, and HPV type distribution in women. Liquid-based cytology samples (SurePath) were...... collected consecutively. HPV testing was performed with Hybrid Capture 2 (HC2; Digene) (high-risk and low-risk probes), and LiPA (Innogenetics) was used for genotyping. We analyzed samples from 11,617 women; 94.0% had normal cytology, 4.3% atypical squamous cells of undetermined significance or low...

  16. ROC curves of obesity indicators have a predictive value for children hypertension aged 7-17 years

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    Li Tai-shun

    2014-08-01

    Full Text Available Objective: The aim of the study is to examine the distribution of integrated covariate and its association with blood pressure (BP among children in Anhui province, China, and assess the predictive value of integrated covariate to children hypertension. Methods: A total of 2,828 subjects (1,588 male and 1,240 female aged 7-17 years participated in this study. Height, weight, waistline, hipline and BP of all subjects were measured, obesity and overweight were defined by an international standard, specifying the measurement, the reference population, and the age and sex specific cut off points. High BP status was defined as systolic blood pressure (SBP and/or diastolic blood pressure (DBP > 95th percentile for age and gender. Results: Our results revealed that the prevalence of children hypertension was 11.03%, the SBP and DBP of obesity group were significantly higher than that of normal group. Anthropometric obesity indices such as body mass index (BMI were positively correlated with SBP and DBP. Integrated covariate had a better performance than the single covariate in the receiver-operating characteristic (ROC curve, the cut-off value; the sensitivity and the specificity of the integrated covariate were 0.112, 0.577, 0.683, respectively. Conclusion: Integrated covariate is a simple and effective anthropometric index to identify childhood hypertension.

  17. ISSUES IN NEUTRON CROSS SECTION COVARIANCES

    Energy Technology Data Exchange (ETDEWEB)

    Mattoon, C.M.; Oblozinsky,P.

    2010-04-30

    We review neutron cross section covariances in both the resonance and fast neutron regions with the goal to identify existing issues in evaluation methods and their impact on covariances. We also outline ideas for suitable covariance quality assurance procedures.We show that the topic of covariance data remains controversial, the evaluation methodologies are not fully established and covariances produced by different approaches have unacceptable spread. The main controversy is in very low uncertainties generated by rigorous evaluation methods and much larger uncertainties based on simple estimates from experimental data. Since the evaluators tend to trust the former, while the users tend to trust the latter, this controversy has considerable practical implications. Dedicated effort is needed to arrive at covariance evaluation methods that would resolve this issue and produce results accepted internationally both by evaluators and users.

  18. Covariant diagrams for one-loop matching

    CERN Document Server

    Zhang, Zhengkang

    2016-01-01

    We present a diagrammatic formulation of recently-revived covariant functional approaches to one-loop matching from an ultraviolet (UV) theory to a low-energy effective field theory. Various terms following from a covariant derivative expansion (CDE) are represented by diagrams which, unlike conventional Feynman diagrams, involve gauge-covariant quantities and are thus dubbed "covariant diagrams." The use of covariant diagrams helps organize and simplify one-loop matching calculations, which we illustrate with examples. Of particular interest is the derivation of UV model-independent universal results, which reduce matching calculations of specific UV models to applications of master formulas. We show how such derivation can be done in a more concise manner than the previous literature, and discuss how additional structures that are not directly captured by existing universal results, including mixed heavy-light loops, open covariant derivatives, and mixed statistics, can be easily accounted for.

  19. Kalman Filtering with Unknown Noise Covariances

    OpenAIRE

    Nilsson, Martin

    2006-01-01

    Since it is often difficult to identify the noise covariances for a Kalman filter, they are commonly considered design variables. If so, we can as well try to choose them so that the corresponding Kalman filter has some nice form. In this paper, we introduce a one-parameter subfamily of Kalman filters with the property that the covariance parameters cancel in the expression for the Kalman gain. We provide a simple criterion which guarantees that the implicitly defined process covariance matri...

  20. Balancing Covariates via Propensity Score Weighting

    OpenAIRE

    Li, Fan; Morgan, Kari Lock; Zaslavsky, Alan M.

    2014-01-01

    Covariate balance is crucial for an unconfounded descriptive or causal comparison. However, lack of balance is common in observational studies. This article considers weighting strategies for balancing covariates. We define a general class of weights-the balancing weights-that balance the weighted distributions of the covariates between treatment groups. These weights incorporate the propensity score to weight each group to an analyst-selected target population. This class unifies existing we...

  1. Co-variations and clustering of chronic disease behavioral risk factors in China: China Chronic Disease and Risk Factor Surveillance, 2007.

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    Yichong Li

    Full Text Available BACKGROUND: Chronic diseases have become the leading causes of mortality in China and related behavioral risk factors (BRFs changed dramatically in past decades. We aimed to examine the prevalence, co-variations, clustering and the independent correlates of five BRFs at the national level. METHODOLOGY/PRINCIPAL FINDINGS: We used data from the 2007 China Chronic Disease and Risk Factor Surveillance, in which multistage clustering sampling was adopted to collect a nationally representative sample of 49,247 Chinese aged 15 to 69 years. We estimated the prevalence and clustering (mean number of BRFs of five BRFs: tobacco use, excessive alcohol drinking, insufficient intake of vegetable and fruit, physical inactivity, and overweight or obesity. We conducted binary logistic regression models to examine the co-variations among five BRFs with adjustment of demographic and socioeconomic factors, chronic conditions and other BRFs. Ordinal logistic regression was constructed to investigate the independent associations between each covariate and the clustering of BRFs within individuals. Overall, 57.0% of Chinese population had at least two BRFs and the mean number of BRFs is 1.80 (95% confidence interval: 1.78-1.83. Eight of the ten pairs of bivariate associations between the five BRFs were found statistically significant. Chinese with older age, being a male, living in rural areas, having lower education level and lower yearly household income experienced increased likelihood of having more BRFs. CONCLUSIONS/SIGNIFICANCE: Current BRFs place the majority of Chinese aged 15 to 69 years at risk for the future development of chronic disease, which calls for urgent public health programs to reduce these risk factors. Prominent correlations between BRFs imply that a combined package of interventions targeting multiple BRFs might be appropriate. These interventions should target elder population, men, and rural residents, especially those with lower SES.

  2. Prevalence and factors associated with trachoma among children aged 1–9 years in Zala district, Gamo Gofa Zone, Southern Ethiopia

    Science.gov (United States)

    Mengistu, Kassahun; Shegaze, Mulugeta; Woldemichael, Kifle; Gesesew, Hailay; Markos, Yohannes

    2016-01-01

    Background Trachoma is the leading cause of preventable blindness worldwide. It is common in areas where people are socioeconomically deprived. Globally, approximately 1.2 billion people live in trachoma-endemic areas, in which, 40.6 million individuals have active trachoma and 8.2 million have trichiasis. According to the World Health Organization’s 2007 report, globally close to 1.3 million people are blind due to trachoma, while approximately 84 million suffer from active trachoma. The National Survey (2007) of Ethiopia showed a prevalence of 40.1% active trachoma among children aged 1–9 years. Trachoma is still endemic in most parts of Ethiopia. Objective To assess prevalence of trachoma and factors associated with it among children aged 1–9 years in Zala district, Gamo Gofa Zone, Southern Nations, Nationalities, and Peoples’ Region. Methods A community-based cross-sectional study was conducted in Zala district from February 28 to March 26, 2014. A total of 611 children were examined for trachoma based on the simplified World Health Organization 1983 classification. A multistage stratified sampling technique with a systematic random sampling technique was used to select study participants. Data were collected by using a semistructured pretested questionnaire and clinical eye examination. The data were entered using EpiData version 3.1 and analyzed using SPSS version 16. Multivariable logistic regression analysis was used to identify independently associated factors. Results The overall prevalence of active trachoma cases was 224 (36.7%) consisting of 207 (92.4%) trachomatous follicles, eight (3.6%) trachomatous intense, and nine (4.0%) combination of trachomatous follicle and trachomatous intense. Inadequate knowledge of family head about trachoma (adjusted odds ratio [AOR] =2.8 [95% CI: 1.9, 4.2]); ≤10 m latrine distance (AOR =1.6 [95% confidence interval {CI}: 1.09, 2.4]); presence of above two preschool children (AOR =2.2 [95% CI: 1.3, 3.7]), flies

  3. Low prevalence of pneumococcal carriage and high serotype and genotype diversity among adults over 60 years of age living in Portugal.

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    Sónia T Almeida

    Full Text Available Pneumococcal disease is frequent at the extremes of age. While several studies have looked at colonization among young children, much less is known among the elderly. We aimed to evaluate pneumococcal carriage among elderly adults living in Portugal. Between April 2010 and December 2012, nasopharyngeal and oropharyngeal swabs of adults over 60 years of age, living in an urban area (n = 1,945 or in a rural area (n = 1,416, were obtained. Pneumococci were isolated by culture-based standard procedures, identified by optochin susceptibility, bile solubility and PCR screening for lytA and cpsA, and characterized by antibiotype, serotype, and MLST. Associations between pneumococcal carriage, socio-demographic and clinical characteristics were evaluated by univariate analysis and multiple logistic regression. The global prevalence of carriage was 2.3% (95% CI: 1.8-2.8. In the multiple logistic regression analysis, smoking, being at a retirement home, and living in a rural area increased the odds of being a pneumococcal carrier by 4.4-fold (95% CI: 1.9-9.2, 2.0-fold (95% CI: 1.1-3.6 and 2.0-fold (95% CI: 1.2-3.5, respectively. Among the 77 pneumococcal isolates, 26 serotypes and 40 STs were identified. The most prevalent serotypes were (in decreasing order 19A, 6C, 22F, 23A, 35F, 11A, and 23B, which accounted, in total, for 60.0% of the isolates. Most isolates (93.5% had STs previously described in the MLST database. Resistance to macrolides, non-susceptibility to penicillin and multidrug resistance were found in 19.5%, 11.7%, and 15.6% of the isolates, respectively. We conclude that the prevalence of pneumococcal carriage in the elderly, in Portugal, as determined by culture-based methods, is low. Serotype and genotype diversity is high. Living in a rural area, in a retirement home, and being a smoker increased the risk of pneumococcal carriage. This study contributes to the establishment of a baseline that may be used to monitor how novel

  4. Conformal covariance and the split property

    CERN Document Server

    Morinelli, Vincenzo; Weiner, Mihály

    2016-01-01

    We show that for a conformal local net of observables on the circle, the split property is automatic. Both full conformal covariance (i.e. diffeomorphism covariance) and the circle-setting play essential roles in this fact, while by previously constructed examples it was already known that even on the circle, M\\"obius covariance does not imply the split property. On the other hand, here we also provide an example of a local conformal net living on the two-dimensional Minkowski space, which - although being diffeomorphism covariant - does not have the split property.

  5. 平凉市中老年男性性功能调查报告%Prevalence of aging male sexual dysfunction in Pingliang City

    Institute of Scientific and Technical Information of China (English)

    韩晓峰; 任江玲; 胡黎明; 许克新

    2011-01-01

    目的 调查平凉市中老年男性性欲低下、勃起功能障碍(erectile dysfunction,ED)、射精障碍的患病情况.方法 采用分层多阶段整群不等比例随机抽样方法,选择城区6个居委会和郊区20个行政村1539名年龄≥50岁男性作为调查对象,分别记录国际勃起功能问卷(IIEF-5)评分及男性性功能问卷(O'Leafy 1995)评分,应用χ2检验分析调查数据.结果 符合标准的调查对象1 230人,年龄50~89(62.5±9.6)岁.平均IIEF-5(9.4±8.6)分.以IIEF-5评分0~21分诊断为ED,总ED患病率92.27%,性欲低下57.96%,射精障碍36.91%.各年龄组间(10岁/组)ED、性欲低下、射精障碍患病率差异有统计学意义(P<0.0001),各年龄组间不同程度ED患病率差异有统计学意义(P<0.0001).结论 随年龄增加ED、性欲低下、射精障碍的患病率逐渐增加,ED患病率最高.%Objective To investigate the prevalence of aging male sexual dysfunction in Pingliang City, Gansu Province.MethodS A cross-sectional study was performed in 6 urban communities and 20 villages in the suburbs of Jingning County,with 1539 males aged over 50 enrolled. The International Index of Erectile Function-5 (IIEF-5) and Brief Male Scxual Function Inventory foi Urology (O' Leary 1995) were recorded and analyzed. Results 1230 subjects were included in the survey, average age (62. 5± 9. 6) years, ranging 50~89. The mean score of IIEF-5 was 9. 4± 8. 6. The prevalence of erectile dysfunction (ED) , defined as IIEF-5 between 0~21, was 92. 27% . The incidence of reduction of sexual desire and defective ejaculation was 57 . 96 % and 36 . 91% , respectively. There was positive correlation between the prevalence of ED. reduction of sexual desire, defective ejaculation and age. Conclusions The incidence of ED, reduction of sexual desire and defective ejaculation are positively correlated with age. And ED ranks the first among these sexual dysfunctions.

  6. Field Investigation on the Prevalence of Trypanosomiasis in Camels in Relation to Sex, Age, Breed and Herd Size

    Directory of Open Access Journals (Sweden)

    B. Bhutto, J. A. Gadahi, G. Shah1, P. Dewani2 and A.G. Arijo

    2010-07-01

    Full Text Available Blood samples were collected from 240 camels (183 male and 57 female of four breeds from six districts of Sindh. An overall infection was determined as 11.25%. Species of Trypanosoma was identified as Trypanosoma evansi. District wise infection was found to be 2.5, 7.5, 12.5, 15.00, 22.5 and 7.5% in Hyderabad, Mirpur Khas, Umerkot, Badin, Thatta and Larkana, respectively. A higher infection was found in females (15.79% as compared to males (9.84%. Highest (14.96% infection was noted in age group >7 years, followed by 8.57 and 4.65% in 3 to 7 years and less than to 3 years old camels, respectively. Four breeds of camels were surveyed and the highest infection rate was found in Sakrai breed (21.82%, followed by 16.67, 6.15 and 5.95% in Kharai, Sindhi and Dhati breeds respectively. When herd size was considered, infection rate was 1.67, 6.67, 15.00 and 21.67% in herds possessing 1 to 5, 6 to 10, 11 to 20 and more than 20 animals, respectively.

  7. Treatment decisions based on scalar and functional baseline covariates.

    Science.gov (United States)

    Ciarleglio, Adam; Petkova, Eva; Ogden, R Todd; Tarpey, Thaddeus

    2015-12-01

    The amount and complexity of patient-level data being collected in randomized-controlled trials offer both opportunities and challenges for developing personalized rules for assigning treatment for a given disease or ailment. For example, trials examining treatments for major depressive disorder are not only collecting typical baseline data such as age, gender, or scores on various tests, but also data that measure the structure and function of the brain such as images from magnetic resonance imaging (MRI), functional MRI (fMRI), or electroencephalography (EEG). These latter types of data have an inherent structure and may be considered as functional data. We propose an approach that uses baseline covariates, both scalars and functions, to aid in the selection of an optimal treatment. In addition to providing information on which treatment should be selected for a new patient, the estimated regime has the potential to provide insight into the relationship between treatment response and the set of baseline covariates. Our approach can be viewed as an extension of "advantage learning" to include both scalar and functional covariates. We describe our method and how to implement it using existing software. Empirical performance of our method is evaluated with simulated data in a variety of settings and also applied to data arising from a study of patients with major depressive disorder from whom baseline scalar covariates as well as functional data from EEG are available.

  8. Oral administration of Lactobacillus reuteri during the first year of life reduces caries prevalence in the primary dentition at 9 years of age.

    Science.gov (United States)

    Stensson, M; Koch, G; Coric, S; Abrahamsson, T R; Jenmalm, M C; Birkhed, D; Wendt, L-K

    2014-01-01

    The aim of this study was to evaluate the effect on oral health, at age 9 years, of daily oral supplementation with the probiotic Lactobacillus reuteri, strain ATCC 55730, to mothers during the last month of gestation and to children through the first year of life. The study was a single-blind, placebo-controlled, multicenter trial involving 113 children: 60 in the probiotic and 53 in the placebo group. The subjects underwent clinical and radiographic examination of the primary dentition and carious lesions, plaque and gingivitis were recorded. Saliva and plaque were sampled for determination of mutans streptococci (MS) and lactobacilli (LB) in saliva and plaque as well as salivary secretory IgA (SIgA). Forty-nine (82%) children in the probiotic group and 31 (58%) in the placebo group were caries-free (p gingivitis compared to the placebo group (p plaque and dietary habits, but to intake of fluoride supplements (p associated with reduced caries prevalence and gingivitis score in the primary dentition at 9 years of age. PMID:24296746

  9. Prevalence of hypertension among individuals aged 50 years and over and its impact on health related quality of life in a semi-rural area of western Turkey

    Institute of Scientific and Technical Information of China (English)

    Didem Arslantas; Unal Ayranci; Alaettin Unsal; Mustafa Tozun

    2008-01-01

    Background Hypertension is common,especially in individuals aged 40 years and over,and it affects about half of the population aged 60 years and over.This study aimed to determine the frequency and risk factors of hypertension among individuals aged 50 years and over,and to examine its effect on the health related quality of life(HRQOL).Methods This population-based cross-sectional study was conducted in two settlements in a region of western Turkey between March 1 and April 30,2007.A questionnaire concerning life habits associated with hypertension,medical histories,and demographic characteristics was filled in by a face to face interview.The SF·36 scale was used to assess HRQOL Body mass index(BMI)was calculated by measuring the weight and length of the body. Results of 1599 individuals living in the region,1193 participated in the survey(48.3%men and 51.7%women).The overall prevalence rate of hypertension was 59.5%(n=710),being 58.O%in men and 60.9% in women(P>0.05).The variables that most positively influenced hypertension(P≤0.05,for each one)were older age(especially the age group of those aged 60 and over),single,no health insurance,consumption of animal fat in meals,and family history of hypertension.The HRQOL of the patients with hypertension was lower than that of those without hypertension(P≤0.05). The HRQOL was better in hypertensive patients whose blood pressure was under control,whereas it was worse in those with at least one chronic disorder accompanying hypertension(P≤0.05,for each one).Conclusions Great emphasis should be placed on the need for a public health program for the detection,prevention, and control of hypertension,including other risk factors,as well as for the modification of foods and life habits,specifically in individuals who are most likely to be at risk of hypertension.

  10. Prevalence of sexual dysfunction and its associated factors in women aged 40-65 years with 11 years or more of formal education: a population-based household survey

    Directory of Open Access Journals (Sweden)

    Ana L. R. Valadares

    2008-01-01

    Full Text Available OBJECTIVE: To evaluate the prevalence of sexual dysfunction and its associated factors in middle-aged women with 11 years or more of formal education. METHODS: A cross-sectional, population-based study was carried out using an anonymous, self-response questionnaire. A total of 315 Brazilian-born women, 40-65 years of age with 11 years or more of schooling, participated in the study. The instrument used in the evaluation was based on the Short Personal Experiences Questionnaire. Sexual dysfunction was calculated from the mean score of sexual responsiveness (pleasure in sexual activities, excitation and orgasm, frequency of sexual activities and libido. Sociodemographic and clinical factors were evaluated. Poisson multiple regression analysis was carried out and the prevalence ratios with respective 95% confidence intervals (95%CI were calculated. RESULTS: The prevalence of sexual dysfunction was 35.9% among our study population. Multiple regression analysis showed that sexual dysfunction was positively associated with older age (prevalence ratios=1.04; 95%CI:1.01-1.07 and with the presence of hot flashes (prevalence ratios=1.37; 95%CI:1.04-1.80. Having a sexual partner (PR=0.47; 95%CI:0.34-0.65 and feeling well or excellent (prevalence ratios= 0.68; 95%CI: 0.52-0.88 were factors associated with lower sexual dysfunction scores. CONCLUSIONS: Sexual dysfunction was present in more than one-third of women that were 40-65 years of age with 11 years or more of formal education. Within that age group, older age and hot flashes were associated with higher sexual dysfunction scores, whereas feeling well and having a sexual partner were associated with better sexuality.

  11. Evidence-Based Novel Changes in Prevalence and Symptom Characteristics of Spleen Deficiency Syndrome in Persons of Varied Health Status and Different Ages: A Cross-Sectional Observational Study

    Directory of Open Access Journals (Sweden)

    Yin Zhang

    2014-01-01

    Full Text Available Deficiency of the organs is a vital pathophysiologic characteristic in the elderly. A core TCM aging theory is known as aging caused by spleen deficiency syndrome (SDS that can be found in ancient and modern literature. The key objectives of this study were to establish a full-scale trial to evaluate the prevalence, symptom severity, frequency, and distribution of SDS in different age groups as related to health status (healthy, subhealthy, and chronic disease to elucidate the role of spleen deficiency in the aging process and deterioration of health status. This cross-sectional observational study was conducted in 4 hospitals in China. 1390 participants aged 20–79 were interviewed by investigators who completed questionnaires recording prevalence, severity, and frequency of symptoms as well as other relevant information. The results revealed that prevalence and symptom characteristics of SDS showed regularities with increasing age and deteriorating health status. It supports the TCM concept that spleen deficiency is an important mechanism of aging, subhealth, and chronic diseases. Early recognition of the warning signs and symptoms of SDS may lead to intervention and even prevention strategies for subhealth and chronic diseases as well as promotion of healthy aging.

  12. A Covariance NMR Toolbox for MATLAB and OCTAVE

    OpenAIRE

    Short, Timothy; Alzapiedi, Leigh; Brüschweiler, Rafael; Snyder, David

    2010-01-01

    The Covariance NMR Toolbox is a new software suite that provides a streamlined implementation of covariance-based analysis of multi-dimensional NMR data. The Covariance NMR Toolbox uses the MATLAB or, alternatively, the freely available GNU OCTAVE computer language, providing a user-friendly environment in which to apply and explore covariance techniques. Covariance methods implemented in the toolbox described here include direct and indirect covariance processing, 4D covariance, generalized ...

  13. Prevalence and factors associated with trachoma among children aged 1–9 years in Zala district , Gamo Gofa zone, Southern Ethiopia

    Directory of Open Access Journals (Sweden)

    Mengistu K

    2016-08-01

    Full Text Available Kassahun Mengistu1 Mulugeta Shegaze2 Kifle Woldemichael3 Hailay Gesesew3,4 Yohannes Markos5 1Department of Zonal Health Office, Gamo Goffa Zone, Arba Minch, Ethiopia; 2Department of Nursing, Arba Minch University, Arba Minch, Ethiopia; 3Department of Epidemiology, Jimma University, Jimma, Ethiopia; 4Discipline of Public Health, Flinders University, Adelaide, Australia; 5Department of Medical Physiology, Jimma University, Jimma, Ethiopia Background: Trachoma is the leading cause of preventable blindness worldwide. It is common in areas where people are socioeconomically deprived. Globally, approximately 1.2 billion people live in trachoma-endemic areas, in which, 40.6 million individuals have active trachoma and 8.2 million have trichiasis. According to the World Health Organization’s 2007 report, globally close to 1.3 million people are blind due to trachoma, while approximately 84 million suffer from active trachoma. The National Survey (2007 of Ethiopia showed a prevalence of 40.1% active trachoma among children aged 1–9 years. Trachoma is still endemic in most parts of Ethiopia.Objective: To assess prevalence of trachoma and factors associated with it among children aged 1–9 years in Zala district, Gamo Gofa Zone, Southern Nations, Nationalities, and Peoples’ Region.Methods: A community-based cross-sectional study was conducted in Zala district from February 28 to March 26, 2014. A total of 611 children were examined for trachoma based on the simplified World Health Organization 1983 classification. A multistage stratified sampling technique with a systematic random sampling technique was used to select study participants. Data were collected by using a semistructured pretested questionnaire and clinical eye examination. The data were entered using EpiData version 3.1 and analyzed using SPSS version 16. Multivariable logistic regression analysis was used to identify independently associated factors.Results: The overall prevalence of

  14. On the Origin of Gravitational Lorentz Covariance

    CERN Document Server

    Khoury, Justin; Tolley, Andrew J

    2013-01-01

    We provide evidence that general relativity is the unique spatially covariant effective field theory of the transverse, traceless graviton degrees of freedom. The Lorentz covariance of general relativity, having not been assumed in our analysis, is thus plausibly interpreted as an accidental or emergent symmetry of the gravitational sector.

  15. Treatment Effects with Many Covariates and Heteroskedasticity

    DEFF Research Database (Denmark)

    Cattaneo, Matias D.; Jansson, Michael; Newey, Whitney K.

    propose a new heteroskedasticity consistent standard error formula that is fully automatic and robust to both (conditional) heteroskedasticity of unknown form and the inclusion of possibly many covariates. We apply our findings to three settings: (i) parametric linear models with many covariates, (ii...

  16. Effect modification by time-varying covariates.

    Science.gov (United States)

    Robins, James M; Hernán, Miguel A; Rotnitzky, Andrea

    2007-11-01

    Marginal structural models (MSMs) allow estimation of effect modification by baseline covariates, but they are less useful for estimating effect modification by evolving time-varying covariates. Rather, structural nested models (SNMs) were specifically designed to estimate effect modification by time-varying covariates. In their paper, Petersen et al. (Am J Epidemiol 2007;166:985-993) describe history-adjusted MSMs as a generalized form of MSM and argue that history-adjusted MSMs allow a researcher to easily estimate effect modification by time-varying covariates. However, history-adjusted MSMs can result in logically incompatible parameter estimates and hence in contradictory substantive conclusions. Here the authors propose a more restrictive definition of history-adjusted MSMs than the one provided by Petersen et al. and compare the advantages and disadvantages of using history-adjusted MSMs, as opposed to SNMs, to examine effect modification by time-dependent covariates. PMID:17875581

  17. Structural covariance networks in the mouse brain.

    Science.gov (United States)

    Pagani, Marco; Bifone, Angelo; Gozzi, Alessandro

    2016-04-01

    The presence of networks of correlation between regional gray matter volume as measured across subjects in a group of individuals has been consistently described in several human studies, an approach termed structural covariance MRI (scMRI). Complementary to prevalent brain mapping modalities like functional and diffusion-weighted imaging, the approach can provide precious insights into the mutual influence of trophic and plastic processes in health and pathological states. To investigate whether analogous scMRI networks are present in lower mammal species amenable to genetic and experimental manipulation such as the laboratory mouse, we employed high resolution morphoanatomical MRI in a large cohort of genetically-homogeneous wild-type mice (C57Bl6/J) and mapped scMRI networks using a seed-based approach. We show that the mouse brain exhibits robust homotopic scMRI networks in both primary and associative cortices, a finding corroborated by independent component analyses of cortical volumes. Subcortical structures also showed highly symmetric inter-hemispheric correlations, with evidence of distributed antero-posterior networks in diencephalic regions of the thalamus and hypothalamus. Hierarchical cluster analysis revealed six identifiable clusters of cortical and sub-cortical regions corresponding to previously described neuroanatomical systems. Our work documents the presence of homotopic cortical and subcortical scMRI networks in the mouse brain, thus supporting the use of this species to investigate the elusive biological and neuroanatomical underpinnings of scMRI network development and its derangement in neuropathological states. The identification of scMRI networks in genetically homogeneous inbred mice is consistent with the emerging view of a key role of environmental factors in shaping these correlational networks.

  18. Geographical Differences in the Population-Based Cross-Sectional Growth Curve and Age at Peak Height Velocity with respect to the Prevalence Rate of Overweight in Japanese Children

    Directory of Open Access Journals (Sweden)

    Masana Yokoya

    2014-01-01

    Full Text Available The School Health Examination Survey is a nationwide examination carried out annually in Japan, and the results are entered into a prefectural-level physical measurement database. We used this database to determine the geographical differences in a population-based cross-sectional growth curve and investigated the association between age at peak height velocity (PHV and the prevalence rate of overweight in children among Japanese prefectures. Mean prefectural-level age at PHV was estimated by the cubic spline-fitting procedure using cross-sectional whole-year prefectural mean height data (5–17 years, 2006–2013, and 8-year (2006–2013 means of the standardized prevalence rates of overweight children and other anatomical data (8-year standardized weight and height were recalculated. Mean prefectural age at PHV was more strongly correlated with the mean prefectural prevalence rate of overweight (age 5–8 years than with other weights or heights in both sexes. On the basis of these findings and their confirmation by multiple regression analysis, the prevalence rate of overweight was selected as a primary factor to explain the geographical difference in age at PHV. These findings suggest that childhood overweight is a dominant factor responsible for the observed geographical differences in onset of puberty in Japan.

  19. Tunneling times with covariant measurements

    CERN Document Server

    Kiukas, J; Werner, R F; 10.1007/s10701-009-9275-z

    2009-01-01

    We consider the time delay of massive, non-relativistic, one-dimensional particles due to a tunneling potential. In this setting the well-known Hartman effect asserts that often the sub-ensemble of particles going through the tunnel seems to cross the tunnel region instantaneously. An obstacle to the utilization of this effect for getting faster signals is the exponential damping by the tunnel, so there seems to be a trade-off between speedup and intensity. In this paper we prove that this trade-off is never in favor of faster signals: the probability for a signal to reach its destination before some deadline is always reduced by the tunnel, for arbitrary incoming states, arbitrary positive and compactly supported tunnel potentials, and arbitrary detectors. More specifically, we show this for several different ways to define ``the same incoming state'' and ''the same detector'' when comparing the settings with and without tunnel potential. The arrival time measurements are expressed in the time-covariant appr...

  20. PREVALENCE OF ANEMIA IN PEDIATRIC AGE GROUP PATIENTS AND ITS CO - RELATION WITH SOCIO - DEMOGRAPHIC FACTORS IN PATIENTS PRESENTING AT DEPARTMENT OF PEDIATRICS AT ROHILKHAND MEDICAL COLLEGE AND HOSPITAL, BAREILLLY, U. P.

    Directory of Open Access Journals (Sweden)

    Tania

    2015-04-01

    Full Text Available BACKGROUND: About 2 billion people are suffering from iron deficiency anemia. India continues to be one of the countries to have highest prevalence of anemia NFHS 3 estimates reveals the prevalence of anemia to be 73% in children aged 5 - 11 years. Present study was und ertaken to determine the prevalence of anemia in pediatric age group from 6 months to 14 years. Aims and objective: To study prevalence of anemia in pediatric age group patients and its co - relation with socio - demographic factors in patients presenting at p ediatrics department R.M.C.H. Bareilly. MATERIAL METHOD S : Cross sectional study was carried out from July 2013 to December 2014. A total of 215 students (115 boys and 100 girls were studied. Parents of subjects aged less than 8 years and patients aged more than 8 years attendants were interviewed using a pretes ted questionnaire. Blood samples were taken by fingers prick method. Hb estimation was done by cyan - met hemoglobin method using calorimeter. SPSS Version 10.0, proportions were calculated and chi square test was used as a test for significance. RESULTS: Ou t of total 215 subjects, 82 (38% were found anemic. Girls were affected more as comp aired to boys. Prevalence of anemia was maximum in children belonging to lower social classes (100.0% followed by upper - lower (45%, lower middle (26% and upper middle ( 22% and this prevalence of anemia in relation to social class was found to be statistically significant (p<0.001 higher in children of illiterate mothers and working mothers (p<0.001. CONCLUSION: In India major factor responsible for nutritional anemia children is delayed weaning and insufficient semisolid and solid food intake.

  1. Analogies and correspondences between variograms and covariance functions

    OpenAIRE

    Gneiting, Tilmann; Sasvári, Zoltán; Schlather, Martin

    2001-01-01

    Variograms and covariance functions are key tools in geostatistics. However, various properties, characterizations, and decomposition theorems have been established for covariance functions only. We present analogous results for variograms and explore the connections with covariance functions. Our findings include criteria for covariance functions on intervals, and we apply them to exponential models, fractional Brownian motion, and locally polynomial covariances. In part...

  2. The prevalence and onset of age of stroke in Chinese adults%我国35岁以上居民脑卒中患病情况和发病年龄

    Institute of Scientific and Technical Information of China (English)

    翟屹; 王文志; 赵文华; 杨晓光; 孔灵芝

    2009-01-01

    Objective To analyze the prevalence and onset of age of stroke in Chinese adults aged 35 years old and above. Methods Data from the 2002 National Nutrition and Health Survey was used to analyze the prevalence of stroke by age, sex, regions, and the differences of onset of age of stroke among the alive patients. Result Standardized prevalence of stroke in Chinese adults aged 35 years old and above was 1111.5 per 100 000,1258.9 per 100 000 in male which was higher than female (959.3 per 100 000). The prevalence of stroke in urban (1544. 8 per 100 000) was higher than that in rural (758. 1 per 100 000). The standardized prevalence of stroke in the north (1479. 3 per 100 000) was significantly higher than that in the south (719. 6 per 100 000). The standardized prevalence of stroke in eastern,central and western region was 1469.0 per 100 000,1085.4 per 100 000,614.9 per 100 000,respectively. It is estimated that there were 5. 627 million patients with stroke aged 35 years old and above in China in 2002. The age at onset of stroke in the alive patients was skewed distribution. Median was 60 years old. The first incidence of stroke within 60 -age group accounted for 32. 4%. The age at onset of stroke was no significantly different between male (60 years old, χ~2 = 0. 00, P > 0. 05) and female ( 60 years old). The median of the age at onset of stroke (61 years old) in urban was higher than that in rural (58 years old,χ~2 = 17. 34,P0.05),城市人群的发病年龄中位数为61岁,晚于农村人群的58岁(χ~2=17.34,P<0.01),东部地区发病年龄中位数(61岁)晚于中部(59岁)和西部地区(57岁)(χ~2=12.92,P<0.01).结论 我国脑卒中患病存在性别及地区差异.现存脑卒中患者中,有1/2以上的患者脑卒中初次发病在60岁以前,即中青年人群.

  3. The covariate-adjusted frequency plot.

    Science.gov (United States)

    Holling, Heinz; Böhning, Walailuck; Böhning, Dankmar; Formann, Anton K

    2016-04-01

    Count data arise in numerous fields of interest. Analysis of these data frequently require distributional assumptions. Although the graphical display of a fitted model is straightforward in the univariate scenario, this becomes more complex if covariate information needs to be included into the model. Stratification is one way to proceed, but has its limitations if the covariate has many levels or the number of covariates is large. The article suggests a marginal method which works even in the case that all possible covariate combinations are different (i.e. no covariate combination occurs more than once). For each covariate combination the fitted model value is computed and then summed over the entire data set. The technique is quite general and works with all count distributional models as well as with all forms of covariate modelling. The article provides illustrations of the method for various situations and also shows that the proposed estimator as well as the empirical count frequency are consistent with respect to the same parameter.

  4. Self-reported medication side effects in an older cohort living independently in the community - the Melbourne Longitudinal Study on Healthy Ageing (MELSHA): cross-sectional analysis of prevalence and risk factors

    OpenAIRE

    Browning Colette; Wang Wei C; Thomson Jennifer A; Kendig Hal L

    2010-01-01

    Abstract Background Medication side effects are an important cause of morbidity, mortality and costs in older people. The aim of our study was to examine prevalence and risk factors for self-reported medication side effects in an older cohort living independently in the community. Methods The Melbourne Longitudinal Study on Healthy Ageing (MELSHA), collected information on those aged 65 years or older living independently in the community and commenced in 1994. Data on medication side effects...

  5. The prevalence and determinants of Chinese medicine use by Australian women: analysis of a cohort of 10,287 women aged 56-61 years.

    Science.gov (United States)

    Sibbritt, David; Adams, Jon; Murthy, Vijayendra

    2013-01-01

    This study aimed to examine the factors associated with Chinese medicine use amongst a sample of 10,287 Australian women aged 56-61 years. Data was obtained from a cross-sectional postal questionnaire conducted in 2007, this being the fifth survey of the Australian Longitudinal Study on Women's Health. This representative sample of 10,287 women was randomly selected from the Health Insurance Commission (Medicare) database. The outcome measure was the use of Chinese medicine in the previous 12 months. The predictive factors included demographics, health status measures and health service utilization measures. Statistical analyses included univariate chi-square and ANOVA tests and backward stepwise multiple logistic regression modelling. The use of Chinese medicine amongst women aged 56-61 years appears to be strongly influenced by their country of birth, consultation with a range of CAM practitioners, and the use of some self-prescribed CAM. Interestingly, severe tiredness was the only symptom or diagnosis that predicted Chinese medicine use. Given the substantial prevalence of Chinese medicine use and the finding that the use of Chinese medicine is heavily integrated alongside the use of many other CAM and conventional treatments, it is imperative for the safety of patients that health professionals (across complementary and conventional healthcare) fully recognise the possible Chinese medicine use amongst their practice populations. In order to help inform relevant practice and policy development it is also important that future research further examining women's decision-making, motivations and evaluations regarding Chinese medicine use considers such issues within the context of broader CAM and conventional health care utilization. PMID:23548119

  6. A Swiss Longitudinal Study of the Prevalence of, and Overlap Between, Sexual Problems in Men and Women Aged 20 to 50 Years Old.

    Science.gov (United States)

    Angst, Jules; Hengartner, Michael P; Rössler, Wulf; Ajdacic-Gross, Vladeta; Leeners, Brigitte

    2015-01-01

    The aim of this study was to obtain data on the development and course of sexual problems and their interrelationships by investigating a representative sample of men and women over a period of 30 years. A representative sample of 299 women selected from the complete electoral register and 292 men selected from screening lists for military service in Zurich, Switzerland, answered questions about their sexuality as part of a series of seven interviews between ages 20 (1979) and 50 (2008). Of the initial sample of 591 participants, 43% (57% of them male) were lost to follow-up. Interviews were conducted using the Structured Psychopathological Interview and Rating of the Social Consequences of Psychological Disturbances for Epidemiology (SPIKE), a semistructured interview. Sexual problems were identified on the basis of the study participants' self-appraisal. One-year prevalence rates, lifetime risks, and overlap of functional, emotional, and sexual desire problems in men and women were evaluated. The findings confirmed higher lifetime risks in women than in men for any sexual problem (females 67.0%; males 46.0%) and for functional (39.3%; 22.1%), emotional (35.7%; 15.9%), and sexual desire problems (51.6%; 33.3%). While in general men's sexual problems increased with age, no such association was observed in women. The overlap of all three problems (functional, emotional, and sexual desire) was reported by 16.9% of women but only 5.0% of men. Although there are commonalities, the type but also the development and, in particular, the overlap of sexual problems in women and men are markedly different. PMID:26132602

  7. Prevalence of Methylphenidate Prescription among School-Aged Children in a Swiss Population: Increase in the Number of Prescriptions in the Swiss Canton of Vaud, from 2002 to 2005, and Changes in Patient Demographics

    Science.gov (United States)

    Gumy, Cedric; Huissoud, Therese; Dubois-Arber, Francoise

    2010-01-01

    Objective: Methylphenidate is prescribed for children and adolescents to treat ADHD. As in many Western countries, the increase in methylphenidate consumption is a public concern in Switzerland. The article discusses the authors' assessment of prescription prevalence in 2002 and 2005 for school-aged children in the canton of Vaud. Method: Pharmacy…

  8. Forecasting Covariance Matrices: A Mixed Frequency Approach

    DEFF Research Database (Denmark)

    Halbleib, Roxana; Voev, Valeri

    This paper proposes a new method for forecasting covariance matrices of financial returns. The model mixes volatility forecasts from a dynamic model of daily realized volatilities estimated with high-frequency data with correlation forecasts based on daily data. This new approach allows...... for flexible dependence patterns for volatilities and correlations, and can be applied to covariance matrices of large dimensions. The separate modeling of volatility and correlation forecasts considerably reduces the estimation and measurement error implied by the joint estimation and modeling of covariance...... matrix dynamics. Our empirical results show that the new mixing approach provides superior forecasts compared to multivariate volatility specifications using single sources of information....

  9. Estimation of Low-Rank Covariance Function

    OpenAIRE

    Koltchinskii, Vladimir; Lounici, Karim; Tsybakov, Alexander B.

    2015-01-01

    We consider the problem of estimating a low rank covariance function $K(t,u)$ of a Gaussian process $S(t), t\\in [0,1]$ based on $n$ i.i.d. copies of $S$ observed in a white noise. We suggest a new estimation procedure adapting simultaneously to the low rank structure and the smoothness of the covariance function. The new procedure is based on nuclear norm penalization and exhibits superior performances as compared to the sample covariance function by a polynomial factor in the sample size $n$...

  10. The prevalence of chronic diseases and major disease risk factors at different ages among 150 000 men and women living in Mexico City: cross-sectional analyses of a prospective study

    Directory of Open Access Journals (Sweden)

    Peto Richard

    2009-01-01

    Full Text Available Abstract Background While most of the global burden from chronic diseases, and especially vascular diseases, is now borne by low and middle-income countries, few large-scale epidemiological studies of chronic diseases in such countries have been performed. Methods From 1998–2004, 52 584 men and 106 962 women aged ≥35 years were visited in their homes in Mexico City. Self reported diagnoses of chronic diseases and major disease risk factors were ascertained and physical measurements taken. Age- and sex-specific prevalences and means were analysed. Results After about age 50 years, diabetes was extremely common – for example, 23.8% of men and 26.9% of women aged 65–74 reported a diagnosis. By comparison, ischaemic heart disease was reported by 4.8% of men and 3.0% of women aged 65–74, a history of stroke by 2.8% and 2.3%, respectively, and a history of cancer by 1.3% and 2.1%. Cancer history was generally more common among women than men – the excess being largest in middle-age, due to breast and cervical cancer. At older ages, the gap narrowed because of an increasing prevalence of prostate cancer. 51% of men and 25% of women aged 35–54 smoked cigarettes, while 29% of men and 41% of women aged 35–54 were obese (i.e. BMI ≥30 kg/m2. The prevalence of treated hypertension or measured blood pressure ≥140/90 mmHg increased about 50% more steeply with age among women than men, to 66% of women and 58% of men aged 65–74. Physical inactivity was highly prevalent but daily alcohol drinking was relatively uncommon. Conclusion Diabetes, obesity and tobacco smoking are highly prevalent among adults living in Mexico City. Long-term follow-up of this and other cohorts will establish the relevance of such factors to the major causes of death and disability in Mexico.

  11. Prevalence study of overweight and obesity in middle-aged and aged community residents in Lanzhou%兰州市社区中老年人群超重和肥胖的现况调查

    Institute of Scientific and Technical Information of China (English)

    赵楠; 杨倩; 汤旭磊; 甄东户; 王静玉; 王丽婷; 麻茜

    2016-01-01

    Objective To investigate the prevalence of overweight/obesity among middle-aged and aged community residents in Lanzhou, to evaluate the correlation between overweight/obesity status and obesity-related diseases, and to analyze the risk factors of obesity.MethodsA cluster sampling study was performed in the community residents aged 40-75 years in Zhangguang Community in Lanzhou. All of them carried on the questionnaire survey, physical measurement and laboratory tests. 4 968 objects were included to statistically analyze the prevalence of overweight/obesity, the correlation between overweight/ obesity status and obesity-related diseases and the risk factors of obesity.Results In this study, the prevalence of overweight and obesity were 37.6% and 10.4% respectively, the males had higher rate of obesity than females (11.9%vs. 9.8%,P<0.05), the rate of overweight in males was significantly higher than females (42.7%vs. 35.7%,P<0.01). The objects in the older, with lower education levels and with hypertension, diabetes, dyslipidemia, metabolic syndrome had higher BMI and higher prevalence of overweight and obesity (P<0.01). Multiple regression analysis indicated that overweight and obesity would increase the risks of hypertension, diabetes, dyslipidemia, metabolic syndrome, and coronary heart disease (OR: 1.013-9.164,P<0.05). Binary regression analysis suggested that senior age, male, irregular exercise and low education level were the risk factors of obesity.Conclusions The rates of overweight and obesity among middle-aged and aged residents were nearly 40% and 10.0% respectively. To prevent and control obesity effectively, more exercise should be advocated, and more attention should be specially paid to elderly males with low education levels.%目的:调查兰州市社区中老年人群超重和肥胖的患病情况、肥胖相关疾病的患病风险以及分析肥胖的相关危险因素。方法整群随机抽取兰州市城关区张广中心社区40~75

  12. Aging, female sex, migration, elevated HDL-C, and inflammation are associated with prevalence of metabolic syndrome among African bank employees

    Directory of Open Access Journals (Sweden)

    Gombet T

    2012-06-01

    Full Text Available Thierry Gombet,1 Benjamin Longo-Mbenza,2 Bertrand Ellenga-Mbolla,1 Meo Stephane Ikama,3 Etienne Mokondjimobe,4 Gisele Kimbally-Kaky,3 Jean-Louis Nkoua,31Emergency Department, University Hospital Center of Brazzaville, Brazzaville, Congo; 2Faculty of Health Sciences, Walter Sisulu University, Mthatha, Eastern Cape, South Africa; 3Department of Cardiology and Internal Medicine, University Hospital Center of Brazzaville, Brazzaville, Congo; 4Laboratory of Biochemistry and Pharmacology, Faculty of Health Sciences, Brazzaville, CongoBackground: The objective of this study was to compare four different criteria for diagnosing metabolic syndrome (MS and to correlate sociodemographic data, liver enzymes, lipids, inflammation, and insulin resistance with MS definitions.Methods: This cross-sectional study included a random number of 126 African bank employees from Brazzaville, Congo.Results: The prevalence of MS varied according to the different definitions used: 4.8% under World Health Organization (WHO criteria, 8.7% under the National Cholesterol Education Program Adult Treatment Panel III (NECP-ATPIII criteria, 14.3% under the International Diabetes Federation (IDF for Europe, and 15.9% by the IDF for Central Africa. According to the IDF, specific cutoff points for the erythrocyte sedimentation rate, ≥13 mm at first hour and ≥30 mm at second hour, defined MS for Central Africa. The best agreement was observed between the IDF for Europe and the IDF for Central Africa (Kappa = 0.938; P < 0.0001 criteria. The worst agreements were between the WHO and IDF for Central Africa (Kappa = 0.419; P < 0.0001 criteria and between the WHO and IDF for Europe (Kappa = 0.462; P < 0.0001 criteria. The NECP-ATPIII criteria did not agree with either the IDF for Europe or the IDF for Central Africa criteria. There was a significant relationship between female sex, aging, elevated liver enzymes, elevated phospholipids, high homeostasis model assessment of insulin

  13. Modular covariance, PCT, spin and statistics

    CERN Document Server

    Guido, D

    1995-01-01

    The notion of modular covariance is reviewed and the reconstruction of the Poincar\\'e group extended to the low-dimensional case. The relations with the PCT symmetry and the Spin and Statistics theorem are described.

  14. Covariant Vertex Operators for Cosmic Strings

    CERN Document Server

    Skliros, Dimitri P

    2009-01-01

    We construct covariant vertex operators for high mass bosonic F-string states and present the first realization of coherent open and closed string states in the covariant gauge. We relate a suitable subclass of the vertex operators constructed to both general and specific classical string solutions. In the process we derive the explicit map from light-cone gauge string states (where the physical interpretation is more direct) to the fully covariant normal ordered vertex operators (where the physical interpretation has hitherto been somewhat obscured by the presence of ghosts, but which is nevertheless more appropriate for amplitude computations in general) by making use of DDF operators. In addition to coherent states, we construct quasi-classical states, in particular monomial and polynomial vertex operators in both lightcone and covariant gauge which lie beyond the leading Regge trajectory and extract via factorization vertex operators produced in tachyon-tachyon, tachyon-massless and massless-massless stri...

  15. Geometric methods for estimation of structured covariances

    CERN Document Server

    Ning, Lipeng; Georgiou, Tryphon

    2011-01-01

    We consider problems of estimation of structured covariance matrices, and in particular of matrices with a Toeplitz structure. We follow a geometric viewpoint that is based on some suitable notion of distance. To this end, we overview and compare several alternatives metrics and divergence measures. We advocate a specific one which represents the Wasserstein distance between the corresponding Gaussians distributions and show that it coincides with the so-called Bures/Hellinger distance between covariance matrices as well. Most importantly, besides the physically appealing interpretation, computation of the metric requires solving a linear matrix inequality (LMI). As a consequence, computations scale nicely for problems involving large covariance matrices, and linear prior constraints on the covariance structure are easy to handle. We compare this transportation/Bures/Hellinger metric with the maximum likelihood and the Burg methods as to their performance with regard to estimation of power spectra with spectr...

  16. The Covariant Picard Groupoid in Differential Geometry

    OpenAIRE

    Waldmann, Stefan

    2005-01-01

    In this article we discuss some general results on the covariant Picard groupoid in the context of differential geometry and interpret the problem of lifting Lie algebra actions to line bundles in the Picard groupoid approach.

  17. Characteristic Polynomials of Sample Covariance Matrices

    OpenAIRE

    Kösters, Holger

    2009-01-01

    We investigate the second-order correlation function of the characteristic polynomial of a sample covariance matrix. Starting from an explicit formula for the generating function, we re-obtain several well-known kernels from random matrix theory.

  18. Covariance Spectroscopy for Fissile Material Detection

    Energy Technology Data Exchange (ETDEWEB)

    Rusty Trainham, Jim Tinsley, Paul Hurley, Ray Keegan

    2009-06-02

    Nuclear fission produces multiple prompt neutrons and gammas at each fission event. The resulting daughter nuclei continue to emit delayed radiation as neutrons boil off, beta decay occurs, etc. All of the radiations are causally connected, and therefore correlated. The correlations are generally positive, but when different decay channels compete, so that some radiations tend to exclude others, negative correlations could also be observed. A similar problem of reduced complexity is that of cascades radiation, whereby a simple radioactive decay produces two or more correlated gamma rays at each decay. Covariance is the usual means for measuring correlation, and techniques of covariance mapping may be useful to produce distinct signatures of special nuclear materials (SNM). A covariance measurement can also be used to filter data streams because uncorrelated signals are largely rejected. The technique is generally more effective than a coincidence measurement. In this poster, we concentrate on cascades and the covariance filtering problem.

  19. Evaluation of covariance for fission neutron spectra

    Energy Technology Data Exchange (ETDEWEB)

    Kawano, Toshihiko; Nakashima, Hideki [Kyushu Univ., Fukuoka (Japan); Ohsawa, Takaaki; Shibata, Keiichi

    1999-02-01

    A covariance evaluation system for the evaluated nuclear data library JENDL-3.2 was established, and the covariance data for fission neutron spectra of {sup 233}U, {sup 235}U, {sup 238}U, {sup 239}Pu were evaluated. Two methods were employed to evaluate the covariance. One is based on the experimental data, and the other is based on a model calculation including some kinds of renormalizations. The latter technique was adopted for the covariance evaluation of the fission neutron spectra in JENDL-3.2. We performed an adjustment of the evaluated fission neutron spectrum of {sup 235}U using the spectrum averaged cross sections for the {sup 27}Al(n, p), {sup 46,47,48}Ti(n, p), {sup 54,56}Fe(n, p), {sup 58}Ni(n, p), {sup 90}Zr(n, 2n) reactions. The adjusted spectrum integrated over energy was found to be unity. (author)

  20. A study of prevalence of Sexually Transmitted Infections & response to syndromic treatment among married women of reproductive age group in rural area of Parol Primary Health Centre under Thane district

    Directory of Open Access Journals (Sweden)

    Vibha V. Gosalia

    2013-05-01

    Full Text Available Objectives To study prevalence of Sexually Transmitted Infections (STIs - symptomatic, clinical & laboratorial& response to syndromic treatment in among STI groups. Design Community based interventional study Setting Rual area-Parol Primary Health Centre(PHC, District Thane, Maharashtra state. Poulation Women of reproductive age groups 15 -45 years Methods Present Community based interventional study was conducted among representative group of 415 women of reproductive age groups who were selected by simple random sampling technique in Parol PHC, District Thane, Maharashtra state. All symptomatic & asymptomatic women were counseled for examination & investigations & given syndromic treatment. Follow-up done to assess impact of syndromic treatment. Main Outcome Prevalence of STI symptomatically was 39%, clinically 32.3% & Laboratorial 26%. After syndromic treatment, prevalence of STIs was significantly reduced. Statistical Analysis Z test Results Of the surveyed women (415, prevalence of STI symptomatically was 39%, clinically 32.3% & Laboratorial 26%. The most common presenting symptom was vaginal discharge (36.4% followed by Burning Micturition (24.7%, Vulval itching (17.3%, Lower abdominal pain (13% & Genital ulcer (8.6%. Clinically, 55.2% women were diagnosed as cervicitis & 44.8% as PID. Laboratorial diagnosed STIs were - vaginal candidiasis 46.3%, Bacterial vaginosis 25%, Trichmoniasis 19.4 %, Genital Herpes 7.4% & HIV 1.9%. After syndromic treatment, prevalence of STIs has statistically significantly reduced. Conclusion Syndromic Rx & health education can definitely reduce STIs.

  1. A postal survey of data in general practice on the prevalence of Acquired Brain Injury (ABI) in patients aged 18-65 in one county in the west of Ireland.

    LENUS (Irish Health Repository)

    Finnerty, Fionnuala

    2009-01-01

    BACKGROUND: Very little is known about the prevalence of acquired brain injury (ABI) in Ireland. ABI prevalence has previously been obtained from Belgian general practitioners using a postal survey. We attempted to ascertain the prevalence of ABI in County Mayo through a postal survey of all general practitioners in the county.The specific objectives of this project were to:1. identify whether general practitioners are a. aware of patients with ABI aged 18-65 in their practices b. able to provide prevalence data on ABI in patients aged 18-65 c. able to provide data on age, gender and patient diagnosis 2. analyse prevalence of ABI from any available data from general practitioners. METHODS: A pilot postal survey was performed initially in order to assess the feasibility of the study. It was established that general practitioners did have the necessary information required to complete the questionnaire. A main postal survey was then undertaken. A postal questionnaire was administered to all general practices in County Mayo in the west of Ireland (n = 59). The response rate was 32.2% (n = 19). RESULTS: General practitioners who replied on behalf of their practice could provide data on patient age, gender and diagnosis. In the nineteen practices, there were 57 patients with ABI. The age-specific prevalence of ABI in the area surveyed was estimated at 183.7 per 100,000. The mean patient population per practice was 2,833 (SD = 950). There were found to be significantly more patients with ABI in rural areas than urban areas (p = 0.006). There were also significant differences in the ages of patients in the different ABI categories. Patients whose ABI was of traumatic origin were significantly younger than those patients with ABI of haemorrhagic origin (p = 0.002). CONCLUSION: Although this is a small-scale study, we have ascertained that general practitioners do have data on patients with ABI. Also, some prevalence data now exist where none was available before. These can

  2. Functional CLT for sample covariance matrices

    CERN Document Server

    Bai, Zhidong; Zhou, Wang; 10.3150/10-BEJ250

    2010-01-01

    Using Bernstein polynomial approximations, we prove the central limit theorem for linear spectral statistics of sample covariance matrices, indexed by a set of functions with continuous fourth order derivatives on an open interval including $[(1-\\sqrt{y})^2,(1+\\sqrt{y})^2]$, the support of the Mar\\u{c}enko--Pastur law. We also derive the explicit expressions for asymptotic mean and covariance functions.

  3. Covariant action for type IIB supergravity

    Science.gov (United States)

    Sen, Ashoke

    2016-07-01

    Taking clues from the recent construction of the covariant action for type II and heterotic string field theories, we construct a manifestly Lorentz covariant action for type IIB supergravity, and discuss its gauge fixing maintaining manifest Lorentz invariance. The action contains a (non-gravitating) free 4-form field besides the usual fields of type IIB supergravity. This free field, being completely decoupled from the interacting sector, has no physical consequence.

  4. Covariate analysis of bivariate survival data

    Energy Technology Data Exchange (ETDEWEB)

    Bennett, L.E.

    1992-01-01

    The methods developed are used to analyze the effects of covariates on bivariate survival data when censoring and ties are present. The proposed method provides models for bivariate survival data that include differential covariate effects and censored observations. The proposed models are based on an extension of the univariate Buckley-James estimators which replace censored data points by their expected values, conditional on the censoring time and the covariates. For the bivariate situation, it is necessary to determine the expectation of the failure times for one component conditional on the failure or censoring time of the other component. Two different methods have been developed to estimate these expectations. In the semiparametric approach these expectations are determined from a modification of Burke's estimate of the bivariate empirical survival function. In the parametric approach censored data points are also replaced by their conditional expected values where the expected values are determined from a specified parametric distribution. The model estimation will be based on the revised data set, comprised of uncensored components and expected values for the censored components. The variance-covariance matrix for the estimated covariate parameters has also been derived for both the semiparametric and parametric methods. Data from the Demographic and Health Survey was analyzed by these methods. The two outcome variables are post-partum amenorrhea and breastfeeding; education and parity were used as the covariates. Both the covariate parameter estimates and the variance-covariance estimates for the semiparametric and parametric models will be compared. In addition, a multivariate test statistic was used in the semiparametric model to examine contrasts. The significance of the statistic was determined from a bootstrap distribution of the test statistic.

  5. Representations of Inverse Covariances by Differential Operators

    Institute of Scientific and Technical Information of China (English)

    Qin XU

    2005-01-01

    In the cost function of three- or four-dimensional variational data assimilation, each term is weighted by the inverse of its associated error covariance matrix and the background error covariance matrix is usually much larger than the other covariance matrices. Although the background error covariances are traditionally normalized and parameterized by simple smooth homogeneous correlation functions, the covariance matrices constructed from these correlation functions are often too large to be inverted or even manipulated. It is thus desirable to find direct representations of the inverses of background errorcorrelations. This problem is studied in this paper. In particular, it is shown that the background term can be written into ∫ dx|Dv(x)|2, that is, a squared L2 norm of a vector differential operator D, called the D-operator, applied to the field of analysis increment v(x). For autoregressive correlation functions, the Doperators are of finite orders. For Gaussian correlation functions, the D-operators are of infinite order. For practical applications, the Gaussian D-operators must be truncated to finite orders. The truncation errors are found to be small even when the Gaussian D-operators are truncated to low orders. With a truncated D-operator, the background term can be easily constructed with neither inversion nor direct calculation of the covariance matrix. D-operators are also derived for non-Gaussian correlations and transformed into non-isotropic forms.

  6. Sequential BART for imputation of missing covariates.

    Science.gov (United States)

    Xu, Dandan; Daniels, Michael J; Winterstein, Almut G

    2016-07-01

    To conduct comparative effectiveness research using electronic health records (EHR), many covariates are typically needed to adjust for selection and confounding biases. Unfortunately, it is typical to have missingness in these covariates. Just using cases with complete covariates will result in considerable efficiency losses and likely bias. Here, we consider the covariates missing at random with missing data mechanism either depending on the response or not. Standard methods for multiple imputation can either fail to capture nonlinear relationships or suffer from the incompatibility and uncongeniality issues. We explore a flexible Bayesian nonparametric approach to impute the missing covariates, which involves factoring the joint distribution of the covariates with missingness into a set of sequential conditionals and applying Bayesian additive regression trees to model each of these univariate conditionals. Using data augmentation, the posterior for each conditional can be sampled simultaneously. We provide details on the computational algorithm and make comparisons to other methods, including parametric sequential imputation and two versions of multiple imputation by chained equations. We illustrate the proposed approach on EHR data from an affiliated tertiary care institution to examine factors related to hyperglycemia. PMID:26980459

  7. PREVALENCE OF IRON DEFICIENCY ANAEMIA AMONG CHILDREN AGED 6 MONTHS-5 YEARS ADMITTED AT KBNTGH AND TO KNOW THE RATES OF PROPHYLACTIC IRON SUPPLEMENTATION, A ONE YEAR RETROSPECTIVE STUDY

    OpenAIRE

    Mujumdar; Siddaling; Preethi; Nabeel; Harshvardhan

    2015-01-01

    The aim of this study was to know the prevalence of Iron Deficiency Anaemia (IDA) among chilsdren aged 6 months-5 years in KBNTGH (Khaja Bandanawaz Teaching and General Hospital attached to Khaja Bandanawaz Institute of Medical Sciences). The files of 1519 patients aged between 0-5 years, who were hospitalized to KBN Hospital Pediatrics Ward were reviewed. A total of 50 patients with anaemia (Haemoglobin: 9gm%) consisting of 35 boys and 15 girls with the mean age of 16.59±1.68 mon...

  8. Mild riboflavin deficiency is highly prevalent in school-age children but does not increase risk for anaemia in Cote d'Ivoire

    NARCIS (Netherlands)

    Rohner, F.; Zimmermann, M.B.; Wegmueller, R.; Tschannen, A.B.; Hurrell, R.F.

    2007-01-01

    There are few data on the prevalence of riboflavin deficiency in sub-Saharan Africa, and it remains unclear whether riboflavin status influences the risk for anaemia. The aims of this study were to: (1) measure the prevalence of riboflavin deficiency in children in south-central Côte d'Ivoire; (2) e

  9. Changes in the Prevalence of Child Sexual Abuse, Its Risk Factors, and Their Associations as a Function of Age Cohort in a Finnish Population Sample

    Science.gov (United States)

    Laaksonen, Toni; Sariola, Heikki; Johansson, Ada; Jern, Patrick; Varjonen, Markus; von der Pahlen, Bettina; Sandnabba, N. Kenneth; Santtila, Pekka

    2011-01-01

    Objective: We examined (1) the prevalence of childhood sexual abuse (CSA) experiences as a function of cohort and gender, (2) the prevalence of factors associated with CSA as a function of cohort and whether the association of these factors with CSA remained the same irrespective of cohort, and (3) whether any cohort differences could be…

  10. Children's Understanding of the Principles of Covariation and Compensation in Part-Whole Relationships.

    Science.gov (United States)

    Irwin, Kathryn C.

    1996-01-01

    Interviews with 107 children, ages 4-7, about uncounted quantities, counted quantities, and numerical equations showed that the ability to predict changes to counted quantities increased with age. Only 7-year olds were able to use covariance and compensation in the purely numerical context of derived equations. (Author/MKR)

  11. Covariance Modifications to Subspace Bases

    Energy Technology Data Exchange (ETDEWEB)

    Harris, D B

    2008-11-19

    Adaptive signal processing algorithms that rely upon representations of signal and noise subspaces often require updates to those representations when new data become available. Subspace representations frequently are estimated from available data with singular value (SVD) decompositions. Subspace updates require modifications to these decompositions. Updates can be performed inexpensively provided they are low-rank. A substantial literature on SVD updates exists, frequently focusing on rank-1 updates (see e.g. [Karasalo, 1986; Comon and Golub, 1990, Badeau, 2004]). In these methods, data matrices are modified by addition or deletion of a row or column, or data covariance matrices are modified by addition of the outer product of a new vector. A recent paper by Brand [2006] provides a general and efficient method for arbitrary rank updates to an SVD. The purpose of this note is to describe a closely-related method for applications where right singular vectors are not required. This note also describes the SVD updates to a particular scenario of interest in seismic array signal processing. The particular application involve updating the wideband subspace representation used in seismic subspace detectors [Harris, 2006]. These subspace detectors generalize waveform correlation algorithms to detect signals that lie in a subspace of waveforms of dimension d {ge} 1. They potentially are of interest because they extend the range of waveform variation over which these sensitive detectors apply. Subspace detectors operate by projecting waveform data from a detection window into a subspace specified by a collection of orthonormal waveform basis vectors (referred to as the template). Subspace templates are constructed from a suite of normalized, aligned master event waveforms that may be acquired by a single sensor, a three-component sensor, an array of such sensors or a sensor network. The template design process entails constructing a data matrix whose columns contain the

  12. Cross sectional study of childhood obesity and prevalence of risk factors for cardiovascular disease and diabetes in children aged 11–13

    Directory of Open Access Journals (Sweden)

    Brophy Sinead

    2009-03-01

    Full Text Available Abstract Background Childhood obesity levels are rising with estimates suggesting that around one in three children in Western countries are overweight. People from lower socioeconomic status and ethnic minority backgrounds are at higher risk of obesity and subsequent CVD and diabetes. Within this study we examine the prevalence of risk factors for CVD and diabetes (obesity, hypercholesterolemia, hypertension and examine factors associated with the presence of these risk factors in school children aged 11–13. Methods and design Participants will be recruited from schools across South Wales. Schools will be selected based on catchment area, recruiting those with high ethnic minority or deprived catchment areas. Data collection will take place during the PE lessons and on school premises. Data will include: anthropometrical variables (height, weight, waist, hip and neck circumferences, skinfold thickness at 4 sites, physiological variables (blood pressure and aerobic fitness (20 metre multi stage fitness test (20 MSFT, diet (self-reported seven-day food diary, physical activity (Physical Activity Questionnire for Adolescents (PAQ-A, accelerometery and blood tests (fasting glucose, insulin, lipids, fibrinogen (Fg, adiponectin (high molecular weight, C-reactive protein (CRP and interleukin-6 (IL-6. Deprivation at the school level will be measured via information on the number of children receiving free school meals. Townsend deprivation scores will be calculated based on the individual childs postcode and self assigned ethnicity for each participating child will be collected. It is anticipated 800 children will be recruited. Multilevel modeling will be used to examine shared and individual factors associated with obesity, stratified by ethnic background, deprivation level and school. Discussion This study is part of a larger project which includes interviews with older children regarding health behaviours and analysis of existing cohort studies

  13. Effect of Home-Based Complementary Food Fortification on Prevalence of Anemia Among Infants and Young Children Aged 6 to 23 Months in Poor Rural Regions of China.

    Science.gov (United States)

    Huo, Junsheng; Sun, Jing; Fang, Zheng; Chang, Suying; Zhao, Liyun; Fu, Ping; Wang, Jie; Huang, Jian; Wang, Lijuan; Begin, France; Hipgrave, David B; Ma, Guansheng

    2015-12-01

    Following the 2008 Wenchuan earthquake, the Chinese government instituted an infant and young and child nutrition program that included promotion of in-home fortification of complementary food with ying yang bao (YYB), a soy-based powder containing iron, 2.5 mg as iron-EDTA and 5 mg as ferrous fumarate, and other micronutrients. Ying yang bao was provided to participating families in 8 poor rural counties in Sichuan, Shaanxi, and Gansu provinces by the Ministry of Health. We assessed hemoglobin levels among infants and young children (IYC) aged 6 to 23 months at baseline in May 2010 (n = 1290) and during follow-up in November 2010 (n = 1142), May 2011 (n = 1118), and November 2011 (n = 1040), using the Hemocue method. Interviewers collected basic demographic information and child feeding practices from the children's caretakers. Altitude-adjusted hemoglobin level averaged 10.8 g/dL, and total anemia prevalence was 49.5% at baseline. Average hemoglobin was 11.3 g/dL at 6 months, 11.6 g/dL at 12 months, and 11.7 g/dL at 18 months after introduction of YYB. Moderate anemia (hemoglobin: 70-99 g/dL) decreased from 20.3% at baseline to 7.5%, 5.8%, and 7.3% after 6, 12, and 18 months of home fortification, respectively (P anemia (hemoglobin: 100-110 g/dL) decreased from 29.0% to 16.7%, 18.1%, and 15.4%, respectively (P anemia rates. Home food fortification with YYB is feasible and effective for nutrition promotion among IYC in high-risk regions of China.

  14. Increased Prevalence 12308 A > G mutation in Mitochondrial tRNALeu (CUN Gene Associated with earlier Age of Onset in Friedreich Ataxia

    Directory of Open Access Journals (Sweden)

    Mohammad Medhi HEIDARI

    2011-12-01

    Full Text Available How to Cite this Article: Heidari MM, Khatami M, Houshmand M, Mahmoudi E, Nafissi Sh .Increased Prevalence 12308 A > G mutation in MitochondrialtRNALeu (CUN Gene Associated with earlier Age of Onset in Friedreich Ataxia. Iranian Journal of Child Neurology 2011;5(4:25-31.Objective Friedreich ataxia (FRDA is an inherited recessive disorder. Mitochondrial DNA is a candidate modifying factor for FRDA.The purpose of this study was to investigate the relationship between the tRNALeu (CUN 12308 A> G mutation and age of onset in Friedreich ataxia.Materials & Methods The 12308 A> G substitution in mitochondrial tRNALeu (CUN was examined in DNA samples from 30 Friedreich ataxia patients and 48 control subjects by temporal temperature gradient gel electrophoresis (TTGE and sequencing. Logistic regression was used to determine of cutoff age of onset.ResultsTwenty-two patients had the 12308 A> G mutation, and we found that its overall prevalence was significantly higher in 20 patients aged 17 years or younger than in 2 patients aged over 17 years (90% versus 10%. The 12308 A> G mutation lies in a region that has been highly conserved between species.Conclusion Our results show that the 12308 A > G mutation is associated with earlier age of onset in Friedreich ataxia. Thus, this mutation might cause the younger age of onset in FRDA.References Grabczyk E, Usdin K. The GAA*TTC triplet repeat expanded in Friedreich ataxia impedes transcription elongation by T7 RNA polymerase in a length and supercoil dependent manner. Nucleic Acids Res 2000;28(14:2815-22.Sakamoto N, Chastain PD, Parniewski P, Ohshima K, Pandolfo M, Griffith JD, et al. Sticky DNA: self association properties of long GAA.TTC repeats in R.R.Y triplex structures from Friedreich ataxia. Mol Cell1999;3(4:465-75.Lodi R, Cooper JM, Bradley JL, Manners D, Styles P, Taylor DJ, et al. Deficit of in vivo mitochondrial ATP production in patients with Friedreich ataxia. Proc Natl Acad Sci U S A 1999

  15. PREVALENCE OF IRON DEFICIENCY ANAEMIA AMONG CHILDREN AGED 6 MONTHS-5 YEARS ADMITTED AT KBNTGH AND TO KNOW THE RATES OF PROPHYLACTIC IRON SUPPLEMENTATION, A ONE YEAR RETROSPECTIVE STUDY

    Directory of Open Access Journals (Sweden)

    Mujumdar

    2015-12-01

    Full Text Available The aim of this study was to know the prevalence of Iron Deficiency Anaemia (IDA among chilsdren aged 6 months-5 years in KBNTGH (Khaja Bandanawaz Teaching and General Hospital attached to Khaja Bandanawaz Institute of Medical Sciences. The files of 1519 patients aged between 0-5 years, who were hospitalized to KBN Hospital Pediatrics Ward were reviewed. A total of 50 patients with anaemia (Haemoglobin: 9gm% consisting of 35 boys and 15 girls with the mean age of 16.59±1.68 months were included into the study. The prevalence of IDA was 3.29% (Boys: 4.23%, girls: 2.1%. Haemoglobin and haematocrit of these patients was analysed. Hemoglobim and hematocrit of children >24 months were significantly higher than those of the patients with the age of 6–12 months. Of the 28 patients who were older than 12 months, only 44% of them had received a full course of iron supplementation for 8 months. In conclusion, although prophylactic iron supplementation lowered the prevalences of IDA, receiving rates of iron supplementation were not adequate. While IDA is still a public health problem, prophylactic approaches should be carried out more effectively.

  16. A CROSS SECTIONAL STUDY TO ASSESS THE PREVALENCE OF HYPERTENSION AND DIABETES AMONG OBESE AND NON OBESE PERSONS, IN ABOVE 40 YEARS AGE GROUP IN A SLUM AREA OF CHENNAI

    Directory of Open Access Journals (Sweden)

    Syed Hubbe

    2012-04-01

    Full Text Available ABSTRACT: CONTEXT : Obesity is increasing in the developed as well as developing countries. The prevalence of obesity is on the rise among the slum population. Increased incidence of vis ceral adiposity, hypertension, n on insulin dependent diabetes mellitus (NIDDM and coron ary heart disease often cluster in the same individual and there have been speculations that a common mechanism may be responsible for all these pathological conditions. This risk factor constellation, which is associated with an enhanced risk for cardiova scular disease, is referred to as “Syndrome X . AIMS : To assess the prevalence of diabetes and hypertension among obese and non obese in above 40 years age group in a slum area of Chennai. SETTINGS AND DESIGN : Urban slum in Chennai, Cross sectional study . MATERIALS AND METHODS : P r esent study was undertaken in a s lum in Chennai in persons above 4 0 years age group . One slum was selected randomly and the households in the slum were sampled by a systematic random sampling method. A pre - designed and pre - tested questionnaire was used to collect information regarding the socio - demographic profile, the diet pattern , the intake of non - vegetarian and oily foods , past history of hypertension and diabetes . Anthropometric data regarding height and weight was taken to assess body mass index (BMI , blood pressure was checked using mercury column sphygmomanometer and blood gluco se level b y G lucometer. STATISTICAL ANALYSIS : The prevalence was expressed in percentage and the Chi square test was used to find association with the factors. RESULTS : The prevalence of obesity was 13.66% and of overweight was 27.72%. The prevalence of Hy pertension among obese was 39.13%, pre obese 32.39% and non obese 24.93%. The prevalence of Dia betes among obese was 28.98%, pre obese 19.71% and non obese 15.34%. CONCLUSION : There is a rising prevalence of overweight and obesity among the urban slum dwellers. The prevalence of

  17. Nuclear data covariances in the Indian context

    International Nuclear Information System (INIS)

    The topic of covariances is recognized as an important part of several ongoing nuclear data science activities, since 2007, in the Nuclear Data Physics Centre of India (NDPCI). A Phase-1 project in collaboration with the Statistics department in Manipal University, Karnataka (Prof. K.M. Prasad and Prof. S. Nair) on nuclear data covariances was executed successfully during 2007-2011 period. In Phase-I, the NDPCI has conducted three national Theme meetings sponsored by the DAE-BRNS in 2008, 2010 and 2013 on nuclear data covariances. In Phase-1, the emphasis was on a thorough basic understanding of the concept of covariances including assigning uncertainties to experimental data in terms of partial errors and micro correlations, through a study and a detailed discussion of open literature. Towards the end of Phase-1, measurements and a first time covariance analysis of cross-sections for 58Ni (n, p) 58Co reaction measured in Mumbai Pelletron accelerator using 7Li (p,n) reactions as neutron source in the MeV energy region were performed under a PhD programme on nuclear data covariances in which enrolled are two students, Shri B.S. Shivashankar and Ms. Shanti Sheela. India is also successfully evolving a team of young researchers to code nuclear data of uncertainties, with the perspectives on covariances, in the IAEA-EXFOR format. A Phase-II DAE-BRNS-NDPCI proposal of project at Manipal has been submitted and the proposal is undergoing a peer-review at this time. In Phase-2, modern nuclear data evaluation techniques that including covariances will be further studied as a research and development effort, as a first time effort. These efforts include the use of techniques such as that of the Kalman filter. Presently, a 48 hours lecture series on treatment of errors and their propagation is being formulated under auspices of the Homi Bhabha National Institute. The talk describes the progress achieved thus far in the learning curve of the above-mentioned and exciting

  18. Cross-covariance functions for multivariate geostatistics

    KAUST Repository

    Genton, Marc G.

    2015-05-01

    Continuously indexed datasets with multiple variables have become ubiquitous in the geophysical, ecological, environmental and climate sciences, and pose substantial analysis challenges to scientists and statisticians. For many years, scientists developed models that aimed at capturing the spatial behavior for an individual process; only within the last few decades has it become commonplace to model multiple processes jointly. The key difficulty is in specifying the cross-covariance function, that is, the function responsible for the relationship between distinct variables. Indeed, these cross-covariance functions must be chosen to be consistent with marginal covariance functions in such a way that the second-order structure always yields a nonnegative definite covariance matrix. We review the main approaches to building cross-covariance models, including the linear model of coregionalization, convolution methods, the multivariate Matérn and nonstationary and space-time extensions of these among others. We additionally cover specialized constructions, including those designed for asymmetry, compact support and spherical domains, with a review of physics-constrained models. We illustrate select models on a bivariate regional climate model output example for temperature and pressure, along with a bivariate minimum and maximum temperature observational dataset; we compare models by likelihood value as well as via cross-validation co-kriging studies. The article closes with a discussion of unsolved problems. © Institute of Mathematical Statistics, 2015.

  19. Activities on covariance estimation in Japanese Nuclear Data Committee

    Energy Technology Data Exchange (ETDEWEB)

    Shibata, Keiichi [Japan Atomic Energy Research Inst., Tokai, Ibaraki (Japan). Tokai Research Establishment

    1997-03-01

    Described are activities on covariance estimation in the Japanese Nuclear Data Committee. Covariances are obtained from measurements by using the least-squares methods. A simultaneous evaluation was performed to deduce covariances of fission cross sections of U and Pu isotopes. A code system, KALMAN, is used to estimate covariances of nuclear model calculations from uncertainties in model parameters. (author)

  20. Prevalence of Frailty Indicators and Association with Socioeconomic Status in Middle-Aged and Older Adults in a Swiss Region with Universal Health Insurance Coverage: A Population-Based Cross-Sectional Study

    Directory of Open Access Journals (Sweden)

    Idris Guessous

    2014-01-01

    Full Text Available Frailty prevalence in older adults has been reported but is largely unknown in middle-aged adults. We determined the prevalence of frailty indicators among middle-aged and older adults from a general Swiss population characterized by universal health insurance coverage and assessed the determinants of frailty with a special focus on socioeconomic status. Participants aged 50 and more from the population-based 2006–2010 Bus Santé study were included (N = 2,930. Four frailty indicators (weakness, shrinking, exhaustion, and low activity were measured according to standard definitions. Multivariate logistic regressions were used to determine associations. Overall, 63.5%, 28.7%, and 7.8% participants presented no frailty indicators, one frailty indicator, and two or more frailty indicators, respectively. Among middle-aged participants (50–65 years, 75.1%, 22.2%, and 2.7% presented 0, 1, and 2 or more frailty indicators. The number of frailty indicators was positively associated with age, hypertension, and current smoking and negatively associated with male gender, body mass index, waist-to-hip ratio, and serum total cholesterol level. Lower income level but not education was associated with higher number of frailty indicators. Frailty indicators are frequently encountered in both older and middle-aged adults from the Swiss general population. Despite universal health insurance coverage, household income is independently associated with frailty.

  1. Accurate covariance estimation of galaxy-galaxy weak lensing: limitations of jackknife covariance

    CERN Document Server

    Shirasaki, Masato; Miyatake, Hironao; Takahashi, Ryuichi; Hamana, Takashi; Nishimichi, Takahiro; Murata, Ryoma

    2016-01-01

    We develop a method to simulate galaxy-galaxy weak lensing by utilizing all-sky, light-cone simulations. We populate a real catalog of source galaxies into a light-cone simulation realization, simulate the lensing effect on each galaxy, and then identify lensing halos that are considered to host galaxies or clusters of interest. We use the mock catalog to study the error covariance matrix of galaxy-galaxy weak lensing and find that the super-sample covariance (SSC), which arises from density fluctuations with length scales comparable with or greater than a size of survey area, gives a dominant source of the sample variance. We then compare the full covariance with the jackknife (JK) covariance, the method that estimates the covariance from the resamples of the data itself. We show that, although the JK method gives an unbiased estimator of the covariance in the shot noise or Gaussian regime, it always over-estimates the true covariance in the sample variance regime, because the JK covariance turns out to be a...

  2. Progress on Nuclear Data Covariances: AFCI-1.2 Covariance Library

    Energy Technology Data Exchange (ETDEWEB)

    Oblozinsky,P.; Oblozinsky,P.; Mattoon,C.M.; Herman,M.; Mughabghab,S.F.; Pigni,M.T.; Talou,P.; Hale,G.M.; Kahler,A.C.; Kawano,T.; Little,R.C.; Young,P.G

    2009-09-28

    Improved neutron cross section covariances were produced for 110 materials including 12 light nuclei (coolants and moderators), 78 structural materials and fission products, and 20 actinides. Improved covariances were organized into AFCI-1.2 covariance library in 33-energy groups, from 10{sup -5} eV to 19.6 MeV. BNL contributed improved covariance data for the following materials: {sup 23}Na and {sup 55}Mn where more detailed evaluation was done; improvements in major structural materials {sup 52}Cr, {sup 56}Fe and {sup 58}Ni; improved estimates for remaining structural materials and fission products; improved covariances for 14 minor actinides, and estimates of mubar covariances for {sup 23}Na and {sup 56}Fe. LANL contributed improved covariance data for {sup 235}U and {sup 239}Pu including prompt neutron fission spectra and completely new evaluation for {sup 240}Pu. New R-matrix evaluation for {sup 16}O including mubar covariances is under completion. BNL assembled the library and performed basic testing using improved procedures including inspection of uncertainty and correlation plots for each material. The AFCI-1.2 library was released to ANL and INL in August 2009.

  3. Age- and sex-specific prevalence and ten-year risk for cardiovascular disease of all 16 risk factor combinations of the metabolic syndrome - A cross-sectional study

    Directory of Open Access Journals (Sweden)

    Moebus Susanne

    2010-08-01

    Full Text Available Abstract Background Based on the AHA/NHLBI-definition three out of five cardiometabolic traits must be present for the diagnosis of the metabolic syndrome (MetS, resulting in 16 different combination types. The associated cardiovascular risk may however be different and specific combination may be indicative of an increased risk, furthermore little is known to which extent these 16 combinations contribute to the overall prevalence of MetS. Here we assessed the prevalence of all 16 combination types of MetS, analyzed the impact of age and gender on prevalence rates, and estimated the 10-year risk of fatal and non-fatal myocardial infarction (MI of each MetS combination type. Methods We used data of the German Metabolic and Cardiovascular Risk Project (GEMCAS, a cross-sectional study, performed during October 2005, including 35,869 participants (aged 18-99 years, 61% women. Age-standardized prevalence and 10-year PROCAM and ESC risk scores for MI were calculated. Results In both men and women the combination with elevated waist-circumference, blood pressure and glucose (WC-BP-GL was the most frequent combination (28%, however a distinct unequal distribution was observed regarding age and sex. Any combination with GL was common in the elderly, whereas any combination with dyslipidemia and without GL was frequent in the younger. Men without MetS had an estimated mean 10-year risk of 4.7% (95%-CI: 4.5%-4.8% for MI (PROCAM, whereas the mean 10-year risk of men with MetS was clearly higher (age-standardized 7.9%; 7.8-8.0%. In women without MetS the mean 10-year risk for MI was 1.1%, in those with MetS 2.3%. The highest impact on an estimated 10-year risk for MI (PROCAM was observed with TG-HDL-GL-BP in both sexes (men 14.7%, women 3.9%. However, we could identify combinations with equal risks of non-fatal and fatal MI compared to participants without MetS. Conclusions We observed large variations in the prevalence of all 16 combination types and their

  4. Prevalence of and interventions for sarcopenia in ageing adults : a systematic review : Report of the International Sarcopenia Initiative (EWGSOP and IWGS)

    OpenAIRE

    Alfonso J. Cruz-Jentoft; Landi, Francesco; Schneider, Stéphane M.; Zúñiga, Clemente; Arai, Hidenori; Boirie, Yves,; Chen, Liang-Kung; Fielding, Roger A.; Martin, Finbarr C; Michel, Jean-Pierre; Sieber, Cornel; Stout, Jeffrey R; Studenski, Stephanie A.; Vellas, Bruno; Woo, Jean

    2014-01-01

    OBJECTIVE: to examine the clinical evidence reporting the prevalence of sarcopenia and the effect of nutrition and exercise interventions from studies using the consensus definition of sarcopenia proposed by the European Working Group on Sarcopenia in Older People (EWGSOP). METHODS: PubMed and Dialog databases were searched (January 2000-October 2013) using pre-defined search terms. Prevalence studies and intervention studies investigating muscle mass plus strength or function outcome measure...

  5. Bacterial Load of Pneumococcal Serotypes Correlates with Their Prevalence and Multiple Serotypes Is Associated with Acute Respiratory Infections among Children Less Than 5 Years of Age

    OpenAIRE

    Bhim Gopal Dhoubhadel; Michio Yasunami; Hien Anh Thi Nguyen; Motoi Suzuki; Thu Huong Vu; Ai Thi Thuy Nguyen; Duc Anh Dang; Lay-Myint Yoshida; Koya Ariyoshi

    2014-01-01

    BACKGROUND: Among pneumococcal serotypes, some serotypes are more prevalent in the nasopharynx than others; determining factors for higher prevalence remain to be fully explored. As non-vaccine serotypes have emerged after the introduction of 7-valent conjugate vaccines, study of serotype specific epidemiology is in need. When two or more serotypes co-colonize, they evolve rapidly to defend host's immune responses; however, a clear association of co-colonization with a clinical outcome is lac...

  6. Prevalence of Nocturnal Enuresis in School aged Children of Iran : Role of Personal and Parents Related Socio- Economic and Educational Factors

    OpenAIRE

    Hashem Mahmoodzadeh; Morteza Amestejani; Mohammad Karamyar; Ahmad-Ali Nikibakhsh

    2013-01-01

    Objective: Nocturnal enuresis is a common psychosocial concern for both parents and children. In the present study we have determined the prevalence of nocturnal enuresis in Iranian children and associated personal and familial factors with this problem.Methods: A cross sectional epidemiological study for detection of nocturnal enuresis prevalence rate and evaluation of associated familial and personal factors in elementary school children [7-11 years old] from Urmia were investigated. The su...

  7. Prevalence of IgG Antibodies against Human Papillomavirus (HPV) type 6, 11, 16, and 18 Virus-Like Particles in Women of Childbearing Age in Port Harcourt, Nigeria.

    Science.gov (United States)

    Okonko, I O; Ofoedu, V

    2015-01-01

    Most HPV prevalence studies have been carried out in high-resource countries with few studies focused on low-resource regions where highest HPV prevalence in the world occurs. This study reports on prevalence of IgG antibodies against HPVs among women of childbearing age in Port Harcourt, Nigeria. One hundred and eighty-two consented women (age-range 19-45 years) were consecutively recruited. Demographic/behavioral data and 5 mL blood samples were collected from each woman. Plasma of each sample was assayed for HPV-6/11/16/18 virus-like particles using a HPV IgG ELISA kit. The overall anti-HPV prevalence was 4.9% while 7.7% with itching/wound in the private part tested positive. Most (88.9%) of the seropositive women were sexually active. Group-specific seropositivity was low (0.0-10.0%). It also showed that all the 9(100.0%) who tested positive to the HPV responded "yes" to no information on the source of HPV information. Being younger, married, high educational level, religion, and lack of information on HPV were the main correlates of HPV positivity among these women. None was vaccinated and would have been naturally exposed to at least one of HPV-6/11/16/18. With 4.9% seropositivity and lack of information regarding HPV among these women, this study recommends a statewide enlightenment campaign and vaccination.

  8. Prevalence of self-reported chronic diseases in individuals over the age of 40 in São Paulo, Brazil: the Platino study Prevalência de doenças crônicas autorrelatadas em indivíduos acima de 40 anos em São Paulo, Brasil: estudo Platino

    Directory of Open Access Journals (Sweden)

    Andréa K. Carvalho

    2012-05-01

    Full Text Available Few studies have been conducted to determine the prevalence of chronic diseases and its impact in individuals aged 40 years or over in Brazil. The objective of this study is to evaluate the prevalence of some common chronic diseases in the Brazilian subgroup assessed by the PLATINO study using a self-reported survey. A total of 918 individuals (55% women with a mean age of 54.6 ± 10.9 years were evaluated. The most prevalent diseases were obesity (62.5%, hypertension (39.2% and gastritis (30.9%. We conclude from this study that there is a high prevalence of chronic diseases in the population over 40 years of age: 88% of the population suffers from a minimum of one disease and 26% of the sample suffers from at least three diseases. We also observed that the number of comorbidities increases with age.Poucos estudos foram desenvolvidos para determinar a prevalência de doenças crônicas e suas associações em indivíduos com mais de 40 anos de idade no Brasil. O objetivo deste trabalho foi avaliar a prevalência de algumas doenças crônicas altamente prevalentes no país, de modo autorreferido, avaliadas no Estudo PLATINO em São Paulo, em uma amostra de base populacional. Novecentos e dezoito indivíduos (55% mulheres com média de idade de 54,6 ± 10,9 anos foram avaliados. As três doenças mais prevalentes foram obesidade (62,5%, hipertensão (39,2% e gastrite (30,9%. Há uma alta prevalência de doenças crônicas na população acima de 40 anos: 88% da amostra apresentaram pelo menos uma doença e 26%, pelo menos, três doenças; e o número de doenças apresentava tendência a aumentar com a idade.

  9. Manifest Covariant Hamiltonian Theory of General Relativity

    CERN Document Server

    Cremaschini, Claudio

    2016-01-01

    The problem of formulating a manifest covariant Hamiltonian theory of General Relativity in the presence of source fields is addressed, by extending the so-called "DeDonder-Weyl" formalism to the treatment of classical fields in curved space-time. The theory is based on a synchronous variational principle for the Einstein equation, formulated in terms of superabundant variables. The technique permits one to determine the continuum covariant Hamiltonian structure associated with the Einstein equation. The corresponding continuum Poisson bracket representation is also determined. The theory relies on first-principles, in the sense that the conclusions are reached in the framework of a non-perturbative covariant approach, which allows one to preserve both the 4-scalar nature of Lagrangian and Hamiltonian densities as well as the gauge invariance property of the theory.

  10. PREVALENCE OF REFRACTIVE ERROR AND OTHER OCULAR MORBIDITIES AND FOLLOW-UP STUDY ON COMPLIANCE TO SPECTACLES USE AMONG SCHOOL GOING CHILDREN AGED 9-16 YEARS IN SELECTED VILLAGE OF HASSAN

    OpenAIRE

    Sumana; Sreelatha; Krishna; Kruthi; Anjan

    2015-01-01

    BACKGROUND Uncorrected refractive errors are the most common cause of visual impairment in school children in India. AIMS AND OBJECTIVES To find out prevalence and risk factors of refractive error. To identify other ocular morbidities and to assess the compliance to spectacle use. SETTINGS AND DESIGN A cross-sectional study was carried out in school going children of age group 9-16 yrs. in Salagame, Hassan. METHODS AND MATERIALS All school going...

  11. A covariant formulation of classical spinning particle

    CERN Document Server

    Cho, J H; Kim, J K; Jin-Ho Cho; Seungjoon Hyun; Jae-Kwan Kim

    1994-01-01

    Covariantly we reformulate the description of a spinning particle in terms of the which entails all possible constraints explicitly; all constraints can be obtained just from the Lagrangian. Furthermore, in this covariant reformulation, the Lorentz element is to be considered to evolve the momentum or spin component from an arbitrary fixed frame and not just from the particle rest frame. In distinction with the usual formulation, our system is directly comparable with the pseudo-classical formulation. We get a peculiar symmetry which resembles the supersymmetry of the pseudo-classical formulation.

  12. Parametric number covariance in quantum chaotic spectra.

    Science.gov (United States)

    Vinayak; Kumar, Sandeep; Pandey, Akhilesh

    2016-03-01

    We study spectral parametric correlations in quantum chaotic systems and introduce the number covariance as a measure of such correlations. We derive analytic results for the classical random matrix ensembles using the binary correlation method and obtain compact expressions for the covariance. We illustrate the universality of this measure by presenting the spectral analysis of the quantum kicked rotors for the time-reversal invariant and time-reversal noninvariant cases. A local version of the parametric number variance introduced earlier is also investigated. PMID:27078354

  13. Notes on Cosmic Censorship Conjecture revisited: Covariantly

    CERN Document Server

    Hamid, Aymen I M; Maharaj, Sunil D

    2016-01-01

    In this paper we study the dynamics of the trapped region using a frame independent semi-tetrad covariant formalism for general Locally Rotationally Symmetric (LRS) class II spacetimes. We covariantly prove some important geometrical results for the apparent horizon, and state the necessary and sufficient conditions for a singularity to be locally naked. These conditions bring out, for the first time in a quantitative and transparent manner, the importance of the Weyl curvature in deforming and delaying the trapped region during continual gravitational collapse, making the central singularity locally visible.

  14. Modular invariance and covariant loop calculus

    International Nuclear Information System (INIS)

    The covariant loop calculus provides and efficient technique for computing explicit expressions for the density on moduli space corresponding to arbitrary (bosonic string) loop diagrams. Since modular invariance is not manifest, however, we carry out a detailed comparison with known explicit 2- and 3- loop results derived using analytic geometry (1 loop is known to be ok). We establish identity to 'high' order in some moduli and exactly in others. Agreement is found as a result of various non-trivial cancellations, in part related to number theory. We feel our results provide very strong support for the correctness of the covariant loop calculus approach. (orig.)

  15. Parametric number covariance in quantum chaotic spectra.

    Science.gov (United States)

    Vinayak; Kumar, Sandeep; Pandey, Akhilesh

    2016-03-01

    We study spectral parametric correlations in quantum chaotic systems and introduce the number covariance as a measure of such correlations. We derive analytic results for the classical random matrix ensembles using the binary correlation method and obtain compact expressions for the covariance. We illustrate the universality of this measure by presenting the spectral analysis of the quantum kicked rotors for the time-reversal invariant and time-reversal noninvariant cases. A local version of the parametric number variance introduced earlier is also investigated.

  16. A violation of the covariant entropy bound?

    CERN Document Server

    Masoumi, Ali

    2014-01-01

    Several arguments suggest that the entropy density at high energy density $\\rho$ should be given by the expression $s=K\\sqrt{\\rho/G}$, where $K$ is a constant of order unity. On the other hand the covariant entropy bound requires that the entropy on a light sheet be bounded by $A/4G$, where $A$ is the area of the boundary of the sheet. We find that in a suitably chosen cosmological geometry, the above expression for $s$ violates the covariant entropy bound. We consider different possible explanations for this fact; in particular the possibility that entropy bounds should be defined in terms of volumes of regions rather than areas of surfaces.

  17. HPV prevalence at enrollment and baseline results from the Carolina Women’s Care Study, a longitudinal study of HPV persistence in women of college age

    Directory of Open Access Journals (Sweden)

    Banister CE

    2013-07-01

    visits.Results and conclusion: CWCS participants were 70% European American, 24% African American, 3% Latina/Hispanic, and 3% Asian. At enrollment, 32% tested positive for any HPV. HPV16 infection was the most common (18% of infections. Together, HPV16, 66, 51, 52, and 18 accounted for 58% of all HPV infections. Sixty-four percent of all HPV-positive samples contained more than one HPV type, with an average of 2.2 HPV types per HPV-positive participant. We found differences between African American and European American women in the prevalence of HPV infection (38.1% African American, 30.7% European American and abnormal Papanicolaou test results (9.8% African-American, 5.8% European American. While these differences did not reach statistical significance at enrollment, as the longitudinal data of this cohort are analyzed, the sample size will allow us to confirm these results and compare the natural history of HPV infection in college-aged African American and European American women.Keywords: human papillomavirus, Carolina Women’s Care Study, papillomavirus persistence, race/ethnicity, health disparities

  18. Prevalence and metabolic risk factors of nonalcoholic fatty liver disease in a middle-aged and elderly population in Guangzhou%广州市中老年人非酒精性脂肪肝患病率及代谢相关因素分析

    Institute of Scientific and Technical Information of China (English)

    曹意; 王澄; 师雯琦; 朱影影; 陈耿东; 陈裕明

    2015-01-01

    目的 探讨非酒精性脂肪性肝病(NAFLD)在中老年人群中的患病情况及其代谢相关因素.方法 采用横断面调查的方法,通过问卷调查和实验室检测对2 935名广州市中老年人进行资料收集、整理.探讨NAFLD在中老年人群中的患病情况,并采用协方差和logistic回归分析代谢因素与NAFLD患病情况之间的关系.NAFLD的诊断标准采用中华医学会肝脏病学分会脂肪肝和酒精性肝病学组的影像学诊断标准,并且按照其严重程度分为轻、中、重三个等级.结果 广州市中老年人群中NAFLD的患病率为50.6%.NAFLD患者组中WC、BMI、FPG、TG、SBP、DBP以及MS患病率均明显高于对照组,而体力活动水平和HDL-C明显降低(P<0.001).logistic回归分析显示,WC、SBP、DBP、TG、FPG和HDL-C每升高一个标准差其对应NAFLD患病的OR值(95%CI)分别为2.70 (2.45~2.98)、1.47(1.35 ~ 1.59)、1.48(1.37 ~ 1.60)、1.88 (1.66~2.12)、1.25(1.15 ~ 1.36)和0.51 (0.47~0.56).随着NAFLD严重程度不断增加,WC、BMI、TG、SBP、DBP和FPG水平均呈现上升趋势,而HDL-C呈现减少的趋势(P<0.001).结论 中老年人NAFLD患病率较高,MS及相关组分与NAFLD关系密切,其中WC增加对NAFLD患病影响最大.%Objective To investigate the prevalence of nonalcoholic fatty liver disease (NAFLD) and understand the relationship between NAFLD and metabolic risk factors in middle-aged and elderly adults.Methods This cross-sectional study recruited 2 935 subjects in Guangzhou,Guangdong province.Face-to-face interviews and laboratory analyses were conducted to collect general information and other covariates.Analysis of covariance and logistic regression analysis were performed to investigate the relationship between metabolic factors and the prevalence of NAFLD.NAFLD was diagnosed based on standard criteria recommend by the Fatty Liver Disease and Alcoholic Liver Disease Branch of Chinese Hepatology Society,and the degree of

  19. Prevalence of overweight and obesity in children and adolescents from the age range of 2 to 19 years old in Brazil.

    Science.gov (United States)

    Niehues, Janaina R; Gonzales, Ana Inês; Lemos, Robson R; Bezerra, Poliana Penasso; Haas, Patrícia

    2014-01-01

    Introduction. Infant juvenile obesity is currently a worldwide public health problem and it is increasing at alarming rate in the Brazilian population, showing its relevance in terms of public health. Objectives. Determine the prevalence of overweight and obesity in children and adolescents between 2 and 19 years old in different regions of Brazil. Methods. The following electronic databases were searched (from September through November 2013): Medline (PubMed), LILACS, and SciELO, using the descriptors and Boolean operators (obesity) and (overweight) and (child) and (prevalence) and (Brazil). Prospective and/or cross-sectional designs studies were found regarding the prevalence of overweight and obese children and adolescents in the five regions of Brazil. Results. A total of 191 scientific articles were found of which 17 met all inclusion criteria. A higher prevalence of overweight was found in the south (25.7%) and north (28.8%) of the country, and obesity in the southeast (15.4%) and south (10.4%). Conclusions. The scope of the studies was mostly based on municipal coverage, which resulted in limitations for conclusive analysis, showing the need for further studies of prevalence at the national level, with emphasis on public health in obese children and adolescents throughout the Brazilian territory. PMID:24995019

  20. Prevalence of Overweight and Obesity in Children and Adolescents from the Age Range of 2 to 19 Years Old in Brazil

    Directory of Open Access Journals (Sweden)

    Janaina R. Niehues

    2014-01-01

    Full Text Available Introduction. Infant juvenile obesity is currently a worldwide public health problem and it is increasing at alarming rate in the Brazilian population, showing its relevance in terms of public health. Objectives. Determine the prevalence of overweight and obesity in children and adolescents between 2 and 19 years old in different regions of Brazil. Methods. The following electronic databases were searched (from September through November 2013: Medline (PubMed, LILACS, and SciELO, using the descriptors and Boolean operators (obesity and (overweight and (child and (prevalence and (Brazil. Prospective and/or cross-sectional designs studies were found regarding the prevalence of overweight and obese children and adolescents in the five regions of Brazil. Results. A total of 191 scientific articles were found of which 17 met all inclusion criteria. A higher prevalence of overweight was found in the south (25.7% and north (28.8% of the country, and obesity in the southeast (15.4% and south (10.4%. Conclusions. The scope of the studies was mostly based on municipal coverage, which resulted in limitations for conclusive analysis, showing the need for further studies of prevalence at the national level, with emphasis on public health in obese children and adolescents throughout the Brazilian territory.

  1. Prevalence of blindness and low vision and influencing factors for them in aged people of Kunming%昆明市老年人群盲和低视力患病率及其影响因素分析

    Institute of Scientific and Technical Information of China (English)

    吴敏; 朱明

    2009-01-01

    Objective To assess the prevalence of blindness and low vision and correlation factors for them in aged people and more than 50 of Kunming. Methods Prevalence of blindness and low vision and correlation factors for them were studied in aged people and more than 50 of Kunming at June to August,2006. Multi-stage sampling was applied to randomly select 2 760 people. Basic information and ophthalmic examination were collected from these participants. The prevalence of blindness,severe visual impairment(SVI) and visual impairment(Ⅵ) were calculated based on pinhole visual acuity,WHO definition of visual injury(Definition A) and daily visual definition(Definition B). The correlation factors about blindness and low vision were analyzed using STATA 9. Results The response rate was 93.8% about 2 588 people. The prevalence of blindness was 3.2% with Definition A and 3.7% with Definition B, and was 2.3% with Definition A and 2.7% Definition B after age-sex adjustment, respectively. The prevalence of blindness for people aged from 50 to 59, from 60 to 69, from 70 to 79,80 and more than 80 were 0.5% ,2.3% ,6.5% and 11.0% ,respectively,the prevalence of SVI were 0.6%, 2.0%,4.5% and 10.1% ,respectively,and the prevalence of Ⅵ were 2.1% 5.7%, 14.6% and 28.2%, respectively. The prevalence of blindness for poor, middie-income people and wealthy people were 4.8%, 2.8% and 2.7%, respectively, the prevalence of SVI were 2.7%, 7.9% and 2.2%, respectively, and the prevalence of Ⅵ were 9.9%, 13.0% and 8.5% ,respectively. The prevalence of blindness for urban population and rural population were 1.6% and 4.5% ,the prevalence of SVI were 1.4% and 3.6% ,and the prevalence of Ⅵ were 6.0% and 10.4%. Statistical analysis showed that the prevalence of blindness,SVI and Ⅵ were significantly related to age,economic conditions and urban and rural distribution,not related to ethnicity or gender. Conclusion Age, economic conditions and urban and rural distribution axe the main risk factors

  2. Partial covariance based functional connectivity computation using Ledoit-Wolf covariance regularization.

    Science.gov (United States)

    Brier, Matthew R; Mitra, Anish; McCarthy, John E; Ances, Beau M; Snyder, Abraham Z

    2015-11-01

    Functional connectivity refers to shared signals among brain regions and is typically assessed in a task free state. Functional connectivity commonly is quantified between signal pairs using Pearson correlation. However, resting-state fMRI is a multivariate process exhibiting a complicated covariance structure. Partial covariance assesses the unique variance shared between two brain regions excluding any widely shared variance, hence is appropriate for the analysis of multivariate fMRI datasets. However, calculation of partial covariance requires inversion of the covariance matrix, which, in most functional connectivity studies, is not invertible owing to rank deficiency. Here we apply Ledoit-Wolf shrinkage (L2 regularization) to invert the high dimensional BOLD covariance matrix. We investigate the network organization and brain-state dependence of partial covariance-based functional connectivity. Although RSNs are conventionally defined in terms of shared variance, removal of widely shared variance, surprisingly, improved the separation of RSNs in a spring embedded graphical model. This result suggests that pair-wise unique shared variance plays a heretofore unrecognized role in RSN covariance organization. In addition, application of partial correlation to fMRI data acquired in the eyes open vs. eyes closed states revealed focal changes in uniquely shared variance between the thalamus and visual cortices. This result suggests that partial correlation of resting state BOLD time series reflect functional processes in addition to structural connectivity.

  3. Prevalence and causes of visual impairment and blindness among adults with diabetes mellitus aged 40 years and older receiving treatment at government health facilities in the Mopani District, South Africa

    Directory of Open Access Journals (Sweden)

    R.G. Mabaso

    2014-08-01

    Full Text Available This article presents part of the findings of a study conducted to assess the prevalence and causes of visual impairment (VI and blindness among adults with diabetes mellitus (DM receiving treatment at the government health facilities in the Mopani District, South Africa.  This health facility-based cross-sectional study was conducted among 225 Black South African diabetics (161 females and 64 males aged 40-90 years (mean= 61.50 ± 10.49 years at seven different health care facilities. All the participants were examined for VI using an auto-refractor, pinhole disc, an ophthalmoscope, and a logMAR chart. Visual impairment was defined as visual acuity (VA of worse than 6/9.5 but better and equal to 3/60, and blindness as VA of worse than 3/60 to no light perception. The prevalence of uncompensated VI and blindness in the right eyes was 70.6 and 3.6%, respectively. In the left eyes, the prevalence was 72 and 3.1% for VI and blindness respectively. The prevalence of blindness remained the same after optical compensation. The leading causes of uncompensated VI and blindness in both eyes were uncorrected refractive error (RE (49.5%, cataract (24.7%, diabetic retinopathy (3.8% and glaucoma (2.2%. Following optical compensation, the prevalence of compensated VI and blindness in the right eyes was 41.3 and 3.6%, respectively and in the left eyes, the prevalence was 42.2 and 3.1%, respectively. Uncompensated RE and cataract were the common causes of VI and blindness in this sample. The socio-economic status of this population might have contributed to these findings. These results indicate the need for affordable vision examination and spectacles provision as well as cataract surgery services in this population.

  4. Optimal covariate designs theory and applications

    CERN Document Server

    Das, Premadhis; Mandal, Nripes Kumar; Sinha, Bikas Kumar

    2015-01-01

    This book primarily addresses the optimality aspects of covariate designs. A covariate model is a combination of ANOVA and regression models. Optimal estimation of the parameters of the model using a suitable choice of designs is of great importance; as such choices allow experimenters to extract maximum information for the unknown model parameters. The main emphasis of this monograph is to start with an assumed covariate model in combination with some standard ANOVA set-ups such as CRD, RBD, BIBD, GDD, BTIBD, BPEBD, cross-over, multi-factor, split-plot and strip-plot designs, treatment control designs, etc. and discuss the nature and availability of optimal covariate designs. In some situations, optimal estimations of both ANOVA and the regression parameters are provided. Global optimality and D-optimality criteria are mainly used in selecting the design. The standard optimality results of both discrete and continuous set-ups have been adapted, and several novel combinatorial techniques have been applied for...

  5. Linear transformations of variance/covariance matrices

    NARCIS (Netherlands)

    Parois, P.J.A.; Lutz, M.

    2011-01-01

    Many applications in crystallography require the use of linear transformations on parameters and their standard uncertainties. While the transformation of the parameters is textbook knowledge, the transformation of the standard uncertainties is more complicated and needs the full variance/covariance

  6. Econometric analysis of realized covariation: high frequency based covariance, regression, and correlation in financial economics

    DEFF Research Database (Denmark)

    Barndorff-Nielsen, Ole Eiler; Shephard, N.

    2004-01-01

    This paper analyses multivariate high frequency financial data using realized covariation. We provide a new asymptotic distribution theory for standard methods such as regression, correlation analysis, and covariance. It will be based on a fixed interval of time (e.g., a day or week), allowing...... the number of high frequency returns during this period to go to infinity. Our analysis allows us to study how high frequency correlations, regressions, and covariances change through time. In particular we provide confidence intervals for each of these quantities....

  7. Trends in population blood pressure and prevalence, awareness, treatment, and control of hypertension among middle-aged and older adults in a rural area of Northwest China from 1982 to 2010.

    Directory of Open Access Journals (Sweden)

    Yaling Zhao

    Full Text Available OBJECTIVES: To assess trends in average blood pressure levels and prevalence, awareness, treatment, and control of hypertension among adults in a rural area of Northwest China, and to determine associated risk factors. METHODS: Four cross-sectional population-based surveys were conducted between 1982 and 2010 among randomly selected adults in rural areas of Hanzhong, in Northwest China. Data on blood pressure, body mass index, family history of hypertension, and socio-demographic and lifestyle characteristics were collected in similar way by trained investigators in four surveys. Data of 8575 participants aged 35-64 years was analyzed. Averages and proportions were adjusted for age and sex. RESULTS: Average blood pressure in the population has increased since 1982 from 76.9 mm Hg to 79.6 mm Hg in 2010 (diastolic and from 120.9 to 129.7 mm Hg (systolic. Prevalence of hypertension increased from 18.4% in 1982 to 30.5% in 2010, and awareness of hypertension increased from 16.8% to 38.4% in 2010. Treatment of hypertension increased from 1.0% in 1982 to 17.4% in 2010, and control of hypertension increased from 0.1% in 1982 to 3.5% in 2010. All these gradients were statistically significant (P<0.01 for trend. Population blood pressure and prevalence, awareness and treatment of hypertension were positively associated with increasing age, body mass index and having family history of hypertension. CONCLUSIONS: Average blood pressure levels and the prevalence, awareness, treatment and control of hypertension among adults in rural areas of Hanzhong have increased since 1982. However, awareness, treatment and control rates remain low. Public health programs and practical strategies are required to improve prevention and control of hypertension in rural Northwest China. In particular, attention should be given to the elderly and obese, and to those with a family history of hypertension, while raising awareness and treatment among younger adults.

  8. Prevalence of Dental Caries and Periodontal Disease in Mexican American Children Aged 5 to 17 Years: Results from Southwestern HHANES, 1982-83.

    Science.gov (United States)

    Ismail, Amid L.; And Others

    1987-01-01

    Dental caries and periodontal disease in Mexican American children of the southwestern United States occur mainly in molars, lending strong support for the use of fissure sealants as a preventive procedure. This study also reports on the prevalence of fillings decay and gingivitis in this population. (VM)

  9. Prevalence and Correlates of Elevated Blood Pressure in Chinese Children Aged 6-13 Years:a Nationwide School-Based Survey

    Institute of Scientific and Technical Information of China (English)

    ZHAI Yi; LI Wei Rong; SHEN Chong; Frank QIAN; SHI Xiao Ming

    2015-01-01

    Objective To estimate the prevalence of elevated blood pressure (EBP) in Chinese children and identify individual and family factors associated with EBP. Methods A nationwide cross-sectional study was conducted in 2010 using stratified cluster sampling. Participants’ blood pressure was measured, and their parents completed a questionnaire on personal and family characteristics. Prevalence and correlates of EBP were assessed. Results Among a total of 24,333 participants, 20.2% of boys and 16.3% of girls had EBP. The prevalence of EBP increased with the ascending trend of waist circumference, Waist-to-height ratio, and body mass index. The adjusted prevalence ratios (aPRs) for obese boys and girls were 2.50 and 2.97, respectively. Fewer urban boys (16.2%) had EBP than rural boys (21.7%). Boys with a family history of hypertension were 12%more likely to have EBP. Children whose mothers received a college education tended to have lower likelihood of EBP;with an aPR was 0.85 among boys and 0.78 among girls. Conclusion EBP is common among obese students and those who have a family history of hypertension. A negative association between mothers’ education levels and EBP risk in children was found.

  10. Comparison of prevalence of metabolic syndrome in hospital and community-based Japanese patients with schizophrenia

    Directory of Open Access Journals (Sweden)

    Yamashita Hakuei

    2011-09-01

    Full Text Available Abstract Background Lifestyle factors, such as an unbalanced diet and lack of physical activity, may affect the prevalence of metabolic syndrome (MetS in schizophrenic patients. The aim of this study was to compare the MetS prevalence between inpatients and outpatients among schizophrenic population in Japan. Methods We recruited inpatients (n = 759 and outpatients (n = 427 with a Diagnostic and Statistical Manual of Mental Disorders, fourth edition (DSM-IV diagnosis of schizophrenia or schizoaffective disorder from 7 psychiatric hospitals using a cross-sectional design. MetS prevalence was assessed using three different definitions, including the adapted National Cholesterol Education Program Adult Treatment Panel (ATP III-A. Results The overall MetS prevalences based on the ATP III-A definition were 15.8% in inpatients and 48.1% in outpatients. In a logistic regression model with age and body mass index as covariates, being a schizophrenic outpatient, compared to being a schizophrenic inpatient, was a significant independent factor (odds ratio = 3.66 for males, 2.48 for females in the development of MetS under the ATP III-A definition. The difference in MetS prevalence between inpatients and outpatients was observed for all age groups in males and for females over 40 years of age. Conclusions Outpatients with schizophrenia or schizoaffective disorder in Japan had a high prevalence of MetS compared to inpatients. MetS in schizophrenic outpatients should be carefully monitored to minimize the risks. A change of lifestyle might improve MetS in schizophrenic patients.

  11. Carcinogenic HPV prevalence and age-specific type distribution in 40,382 women with normal cervical cytology, ASCUS/LSIL, HSIL, or cervical cancer

    DEFF Research Database (Denmark)

    Kjær, Susanne K; Munk, Christian; Junge, Jette;

    2014-01-01

    BACKGROUND: Assessment of the prevaccination type-specific prevalence of human papillomavirus (HPV) in the general population is important for the prediction of the impact of HPV vaccination. METHODS: We collected consecutively residual specimens from liquid-based cytology samples from 40,382 women...... % in cervical cancer and the corresponding prevalence of HPV16/18/31/33/45/52/58 was 89 %. CONCLUSION: This study forms a valuable starting point for monitoring the effect of HPV vaccination in Denmark. In addition, the particular carcinogenic role of HPV16 and 18 is confirmed and may support a role...... from the general population in Copenhagen, Denmark, during 2002-2005. All samples were tested for high-risk HPV using the Hybrid Capture 2 technique, and genotyping was done using LiPa (Innogenetics). Through linkage with the Pathology Data Bank, we obtained information on the cytology result...

  12. The prevalence of serum antibodies to tick-borne infections in Mbale District, Uganda: The effect of agro-ecological zone, grazing management and age of cattle

    OpenAIRE

    Rubaire-Akiiki, C.; J.Okello-Onen; G.W. Nasinyama; Vaarst, M; Kabagambe, E. K.; W. Mwayi; Musunga, D.; Wandukwa, W.

    2004-01-01

    Between August and October 2000, a cross-sectional study was conducted in smallholder dairy farms in Mbale District, Uganda to assess the prevalence of ticks and tick-borne diseases under different grazing systems and agro-ecological zones and understand the circumstances under which farmers operated. A questionnaire was administered to obtain information on dairy farm circumstances and practices. A total of 102 farms were visited and sera and ticks were collected from 478 animals. Sero-preva...

  13. The prevalence of serum antibodies to tick-borne infections in Mbale District, Uganda: the effect of agro-ecological zone, grazing management and age of cattle.

    Science.gov (United States)

    Rubaire-Akiiki, C; Okello-Onen, J; Nasinyama, G W; Vaarst, M; Kabagambe, E K; Mwayi, W; Musunga, D; Wandukwa, W

    2004-01-01

    Between August and October 2000, a cross-sectional study was conducted in smallholder dairy farms in Mbale District, Uganda to assess the prevalence of ticks and tick-borne diseases under different grazing systems and agro-ecological zones and understand the circumstances under which farmers operated. A questionnaire was administered to obtain information on dairy farm circumstances and practices. A total of 102 farms were visited and sera and ticks were collected from 478 animals. Sero-prevalence of tick-borne diseases was determined using an enzyme-linked immunoassay. Acaricides were used indiscriminately but the intensity of their use varied with the grazing system and zone. Cattle from different farms mixed for various reasons. During the dry seasons farmers have to get additional fodder from outside their farms that can result in importation of ticks. The prevalence of ticks and serum antibodies to tick-borne infections differed across the grazing systems and zones. The highest serum antibody prevalence (>60%) was recorded in the lowland zone under the free range and tethering grazing systems. The lowest tick challenge and serum antibody levels (<50%) were recorded in the midland and upland zones under a zero-grazing system. These findings suggest that endemic stability to East Coast Fever, babesiosis and anaplasmosis is most likely to have existed in the lowland zone, particularly, under the tethering and free-range grazing systems. Also, endemic stability for babesiosis existed in the upland zones. Endemic instability for East Coast Fever existed in the midland and upland zones. These structured observational studies are instrumental in planning of control strategies for ticks and tick borne diseases since production systems and the cattle population at high risk of the diseases in the district have been identified. PMID:15861224

  14. The prevalence of serum antibodies to tick-borne infections in Mbale District, Uganda: The effect of agro-ecological zone, grazing management and age of cattle

    Directory of Open Access Journals (Sweden)

    C. Rubaire-Akiiki

    2004-03-01

    Full Text Available Between August and October 2000, a cross-sectional study was conducted in smallholder dairy farms in Mbale District, Uganda to assess the prevalence of ticks and tick-borne diseases under different grazing systems and agro-ecological zones and understand the circumstances under which farmers operated. A questionnaire was administered to obtain information on dairy farm circumstances and practices. A total of 102 farms were visited and sera and ticks were collected from 478 animals. Sero-prevalence of tick-borne diseases was determined using an enzyme-linked immunoassay. Acaricides were used indiscriminately but the intensity of their use varied with the grazing system and zone. Cattle from different farms mixed for various reasons. During the dry seasons farmers have to get additional fodder from outside their farms that can result in importation of ticks. The prevalence of ticks and serum antibodies to tick-borne infections differed across the grazing systems and zones. The highest serum antibody prevalence (>60% was recorded in the lowland zone under the free range and tethering grazing systems. The lowest tick challenge and serum antibody levels (<50% were recorded in the midland and upland zones under a zero-grazing system. These findings suggest that endemic stability to East Coast Fever, babesiosis and anaplasmosis is most likely to have existed in the lowland zone, particularly, under the tethering and free-range grazing systems. Also, endemic stability for babesiosis existed in the upland zones. Endemic instability for East Coast Fever existed in the midland and upland zones. These structured observational studies are instrumental in planning of control strategies for ticks and tick borne diseases since production systems and the cattle population at high risk of the diseases in the district have been identified.

  15. Annual research review: harms experienced by child users of online and mobile technologies: the nature, prevalence and management of sexual and aggressive risks in the digital age

    OpenAIRE

    Livingstone, Sonia; Peter K. Smith

    2014-01-01

    Aims and scope: The usage of mobile phones and the internet by young people has increased rapidly in the past decade, approaching saturation by middle childhood in developed countries. Besides many benefits, online content, contact or conduct can be associated with risk of harm; most research has examined whether aggressive or sexual harms result from this. We examine the nature and prevalence of such risks, and evaluate the evidence regarding the factors that increase or protect against harm...

  16. Annual Research Review: Harms experienced by child users of online and mobile technologies: the nature, prevalence and management of sexual and aggressive risks in the digital age

    OpenAIRE

    Livingstone, Sonia; Peter K. Smith

    2014-01-01

    Aims and scope The usage of mobile phones and the internet by young people has increased rapidly in the past decade, approaching saturation by middle childhood in developed countries. Besides many benefits, online content, contact or conduct can be associated with risk of harm; most research has examined whether aggressive or sexual harms result from this. We examine the nature and prevalence of such risks, and evaluate the evidence regarding the factors that increase or protect against h...

  17. Group B streptococcus serotype prevalence in reproductive-age women at a tertiary care military medical center relative to global serotype distribution

    OpenAIRE

    Williams Julie; Dehart Mary J; Huang Raywin R; Tinnemore Deborah; James Wesley A; Ippolito Danielle L; Wingerd Mark A; Demons Samandra T

    2010-01-01

    Abstract Background Group B Streptococcus (GBS) serotype (Ia, Ib, II-IX) correlates with pathogen virulence and clinical prognosis. Epidemiological studies of seroprevalence are an important metric for determining the proportion of serotypes in a given population. The purpose of this study was to evaluate the prevalence of individual GBS serotypes at Madigan Healthcare System (Madigan), the largest military tertiary healthcare facility in the Pacific Northwestern United States, and to compare...

  18. Factors contributing to high prevalence of gastrointestinal parasites in children aged 2–15 years in the Punta Cana region of the Dominican Republic

    OpenAIRE

    Palmieri, James R

    2014-01-01

    Kristin Anne Geers Childers, James R Palmieri Department of Microbiology, Infectious and Emerging Diseases, Edward Via College of Osteopathic Medicine–Virginia Campus, Blacksburg, VA, USA Abstract: The prevalence of gastrointestinal parasites and the severity of infection have a profound impact on human health and development, affecting approximately one-third of the world's population. Gastrointestinal diseases, most notably caused by a variety of gastrointestinal parasite...

  19. The Coexistence of asthma and Chronic Ostructive Pulmonary Disease (COPD): prevalence and risk factors in young, middle-aged and elderly people from the general population

    OpenAIRE

    Roberto de Marco; Giancarlo Pesce; Alessandro Marcon; Simone Accordini; Leonardo Antonicelli; Massimiliano Bugiani; Lucio Casali; Marcello Ferrari; Gabriele Nicolini; Maria Grazia Panico; Pietro Pirina; Maria Elisabetta Zanolin; Isa Cerveri; Giuseppe Verlato

    2013-01-01

    Background: The joint distribution of asthma and chronic obstructive pulmonary disease (COPD) has not been well described. This study aims at determining the prevalence of self-reported physician diagnoses of asthma, COPD and of the asthma-COPD overlap syndrome and to assess whether these conditions share a common set of risk factors. Methods: A screening questionnaire on respiratory symptoms, diagnoses and risk factors was administered by mail or phone to random samples of the general It...

  20. Prevalence of arrhythmias among children below 15 years of age with congenital heart diseases attending Mulago National Referral Hospital, Uganda

    OpenAIRE

    Batte, Anthony; Lwabi, Peter; Lubega, Sulaiman; Kiguli, Sarah; Nabatte, Violette; Karamagi, Charles

    2016-01-01

    Background In Uganda, few children with congenital heart diseases (CHD) benefit from early corrective cardiac surgery. These children are at high risk of developing heart failure and electrolyte imbalances; factors which increase their risk of developing arrhythmias. This study aimed to determine the prevalence and factors associated with arrhythmias among children with congenital heart diseases receiving care at Mulago Hospital. Methods This was a cross-sectional study carried out from Augus...

  1. Performance evaluation of sensor allocation algorithm based on covariance control

    Institute of Scientific and Technical Information of China (English)

    2005-01-01

    The covariance control capability of sensor allocation algorithms based on covariance control strategy is an important index to evaluate the performance of these algorithms. Owing to lack of standard performance metric indices to evaluate covariance control capability, sensor allocation ratio, etc, there are no guides to follow in the design procedure of sensor allocation algorithm in practical applications. To meet these demands, three quantified performance metric indices are presented, which are average covariance misadjustment quantity (ACMQ), average sensor allocation ratio (ASAR) and matrix metric influence factor (MMIF), where ACMQ, ASAR and MMIF quantify the covariance control capability, the usage of sensor resources and the robustness of sensor allocation algorithm, respectively. Meanwhile, a covariance adaptive sensor allocation algorithm based on a new objective function is proposed to improve the covariance control capability of the algorithm based on information gain. The experiment results show that the proposed algorithm have the advantage over the preceding sensor allocation algorithm in covariance control capability and robustness.

  2. Covariant holography of a tachyonic accelerating universe

    Energy Technology Data Exchange (ETDEWEB)

    Rozas-Fernandez, Alberto [Consejo Superior de Investigaciones Cientificas, Instituto de Fisica Fundamental, Madrid (Spain); University of Portsmouth, Institute of Cosmology and Gravitation, Portsmouth (United Kingdom)

    2014-08-15

    We apply the holographic principle to a flat dark energy dominated Friedmann-Robertson-Walker spacetime filled with a tachyon scalar field with constant equation of state w = p/ρ, both for w > -1 and w < -1. By using a geometrical covariant procedure, which allows the construction of holographic hypersurfaces, we have obtained for each case the position of the preferred screen and have then compared these with those obtained by using the holographic dark energy model with the future event horizon as the infrared cutoff. In the phantom scenario, one of the two obtained holographic screens is placed on the big rip hypersurface, both for the covariant holographic formalism and the holographic phantom model. It is also analyzed whether the existence of these preferred screens allows a mathematically consistent formulation of fundamental theories based on the existence of an S-matrix at infinite distances. (orig.)

  3. Covariant Gauge Fixing and Canonical Quantization

    CERN Document Server

    McKeon, D G C

    2011-01-01

    Theories that contain first class constraints possess gauge invariance which results in the necessity of altering the measure in the associated quantum mechanical path integral. If the path integral is derived from the canonical structure of the theory, then the choice of gauge conditions used in constructing Faddeev's measure cannot be covariant. This shortcoming is normally overcome either by using the "Faddeev-Popov" quantization procedure, or by the approach of Batalin-Fradkin-Fradkina-Vilkovisky, and then demonstrating that these approaches are equivalent to the path integral constructed from the canonical approach with Faddeev's measure. We propose in this paper an alternate way of defining the measure for the path integral when it is constructed using the canonical procedure for theories containing first class constraints and that this new approach can be used in conjunction with covariant gauges. This procedure follows the Faddeev-Popov approach, but rather than working with the form of the gauge tran...

  4. Model selection for Poisson processes with covariates

    CERN Document Server

    Sart, Mathieu

    2011-01-01

    We observe $n$ inhomogeneous Poisson processes with covariates and aim at estimating their intensities. To handle this problem, we assume that the intensity of each Poisson process is of the form $s (\\cdot, x)$ where $x$ is the covariate and where $s$ is an unknown function. We propose a model selection approach where the models are used to approximate the multivariate function $s$. We show that our estimator satisfies an oracle-type inequality under very weak assumptions both on the intensities and the models. By using an Hellinger-type loss, we establish non-asymptotic risk bounds and specify them under various kind of assumptions on the target function $s$ such as being smooth or composite. Besides, we show that our estimation procedure is robust with respect to these assumptions.

  5. Errors on errors - Estimating cosmological parameter covariance

    CERN Document Server

    Joachimi, Benjamin

    2014-01-01

    Current and forthcoming cosmological data analyses share the challenge of huge datasets alongside increasingly tight requirements on the precision and accuracy of extracted cosmological parameters. The community is becoming increasingly aware that these requirements not only apply to the central values of parameters but, equally important, also to the error bars. Due to non-linear effects in the astrophysics, the instrument, and the analysis pipeline, data covariance matrices are usually not well known a priori and need to be estimated from the data itself, or from suites of large simulations. In either case, the finite number of realisations available to determine data covariances introduces significant biases and additional variance in the errors on cosmological parameters in a standard likelihood analysis. Here, we review recent work on quantifying these biases and additional variances and discuss approaches to remedy these effects.

  6. Covariance and the hierarchy of frame bundles

    Science.gov (United States)

    Estabrook, Frank B.

    1987-01-01

    This is an essay on the general concept of covariance, and its connection with the structure of the nested set of higher frame bundles over a differentiable manifold. Examples of covariant geometric objects include not only linear tensor fields, densities and forms, but affinity fields, sectors and sector forms, higher order frame fields, etc., often having nonlinear transformation rules and Lie derivatives. The intrinsic, or invariant, sets of forms that arise on frame bundles satisfy the graded Cartan-Maurer structure equations of an infinite Lie algebra. Reduction of these gives invariant structure equations for Lie pseudogroups, and for G-structures of various orders. Some new results are introduced for prolongation of structure equations, and for treatment of Riemannian geometry with higher-order moving frames. The use of invariant form equations for nonlinear field physics is implicitly advocated.

  7. On covariance structure in noisy, big data

    Science.gov (United States)

    Paffenroth, Randy C.; Nong, Ryan; Du Toit, Philip C.

    2013-09-01

    Herein we describe theory and algorithms for detecting covariance structures in large, noisy data sets. Our work uses ideas from matrix completion and robust principal component analysis to detect the presence of low-rank covariance matrices, even when the data is noisy, distorted by large corruptions, and only partially observed. In fact, the ability to handle partial observations combined with ideas from randomized algorithms for matrix decomposition enables us to produce asymptotically fast algorithms. Herein we will provide numerical demonstrations of the methods and their convergence properties. While such methods have applicability to many problems, including mathematical finance, crime analysis, and other large-scale sensor fusion problems, our inspiration arises from applying these methods in the context of cyber network intrusion detection.

  8. Covariant Quantization of CPT-violating Photons

    CERN Document Server

    Colladay, D; Noordmans, J P; Potting, R

    2016-01-01

    We perform the covariant canonical quantization of the CPT- and Lorentz-symmetry-violating photon sector of the minimal Standard-Model Extension, which contains a general (timelike, lightlike, or spacelike) fixed background tensor $k_{AF}^\\mu$. Well-known stability issues, arising from complex-valued energy states, are solved by introducing a small photon mass, orders of magnitude below current experimental bounds. We explicitly construct a covariant basis of polarization vectors, in which the photon field can be expanded. We proceed to derive the Feynman propagator and show that the theory is microcausal. Despite the occurrence of negative energies and vacuum-Cherenkov radiation, we do not find any runaway stability issues, because the energy remains bounded from below. An important observation is that the ordering of the roots of the dispersion relations is the same in any observer frame, which allows for a frame-independent condition that selects the correct branch of the dispersion relation. This turns ou...

  9. Twisted Covariant Noncommutative Self-dual Gravity

    CERN Document Server

    Estrada-Jimenez, S; Obregón, O; Ramírez, C

    2008-01-01

    A twisted covariant formulation of noncommutative self-dual gravity is presented. The recent formulation introduced by J. Wess and coworkers for constructing twisted Yang-Mills fields is used. It is shown that the noncommutative torsion is solved at any order of the $\\theta$-expansion in terms of the tetrad and the extra fields of the theory. In the process the first order expansion in $\\theta$ for the Pleba\\'nski action is explicitly obtained.

  10. Twisted covariant noncommutative self-dual gravity

    International Nuclear Information System (INIS)

    A twisted covariant formulation of noncommutative self-dual gravity is presented. The formulation for constructing twisted noncommutative Yang-Mills theories is used. It is shown that the noncommutative torsion is solved at any order of the θ expansion in terms of the tetrad and some extra fields of the theory. In the process the first order expansion in θ for the Plebanski action is explicitly obtained.

  11. Area spectrum in Lorentz covariant loop gravity

    OpenAIRE

    Alexandrov, S.; Vassilevich, D.

    2001-01-01

    We use the manifestly Lorentz covariant canonical formalism to evaluate eigenvalues of the area operator acting on Wilson lines. To this end we modify the standard definition of the loop states to make it applicable to the present case of non-commutative connections. The area operator is diagonalized by using the usual shift ambiguity in definition of the connection. The eigenvalues are then expressed through quadratic Casimir operators. No dependence on the Immirzi parameter appears.

  12. Area spectrum in Lorentz covariant loop gravity

    International Nuclear Information System (INIS)

    We use the manifestly Lorentz covariant canonical formalism to evaluate eigenvalues of the area operator acting on Wilson lines. To this end we modify the standard definition of the loop states to make it applicable to the present case of noncommutative connections. The area operator is diagonalized by using the usual shift ambiguity in the definition of the connection. The eigenvalues are then expressed through quadratic Casimir operators. No dependence on the Immirzi parameter appears

  13. Risk evaluation with enhaced covariance matrix

    CERN Document Server

    Urbanowicz, K; Richmond, P; Holyst, Janusz A.; Richmond, Peter; Urbanowicz, Krzysztof

    2006-01-01

    We propose a route for the evaluation of risk based on a transformation of the covariance matrix. The approach uses a `potential' or `objective' function. This allows us to rescale data from diferent assets (or sources) such that each set then has similar statistical properties in terms of their probability distributions. The method is tested using historical data from both the New York and Warsaw Stock Exchanges.

  14. Torsion and geometrostasis in covariant superstrings

    Energy Technology Data Exchange (ETDEWEB)

    Zachos, C.

    1985-01-01

    The covariant action for freely propagating heterotic superstrings consists of a metric and a torsion term with a special relative strength. It is shown that the strength for which torsion flattens the underlying 10-dimensional superspace geometry is precisely that which yields free oscillators on the light cone. This is in complete analogy with the geometrostasis of two-dimensional sigma-models with Wess-Zumino interactions. 13 refs.

  15. Covariant method for calculating helicity amplitudes

    International Nuclear Information System (INIS)

    We present an alternative approach for calculating helicity amplitudes for processes involving both massless and massive fermions. With this method one can easily obtain covariant expressions for the helicity amplitudes. The final expressions involve only four-vector products and are independent of the basis for γ matrices or specific form of the spinors. We use the method to obtain the helicity amplitudes for several processes involving top quark production. copyright 1996 The American Physical Society

  16. Economical phase-covariant cloning with multiclones

    Institute of Scientific and Technical Information of China (English)

    Zhang Wen-Hai; Ye Liu

    2009-01-01

    This paper presents a very simple method to derive the explicit transformations of the optimal economical to M phase-covariant cloning. The fidelity of clones reaches the theoretic bound [D'Ariano G M and Macchiavello C 2003 Phys. Rcv. A 67 042306]. The derived transformations cover the previous contributions [Delgado Y,Lamata L et al,2007 Phys. Rev. Lett. 98 150502] in which M must be odd.

  17. Bacterial load of pneumococcal serotypes correlates with their prevalence and multiple serotypes is associated with acute respiratory infections among children less than 5 years of age.

    Directory of Open Access Journals (Sweden)

    Bhim Gopal Dhoubhadel

    Full Text Available BACKGROUND: Among pneumococcal serotypes, some serotypes are more prevalent in the nasopharynx than others; determining factors for higher prevalence remain to be fully explored. As non-vaccine serotypes have emerged after the introduction of 7-valent conjugate vaccines, study of serotype specific epidemiology is in need. When two or more serotypes co-colonize, they evolve rapidly to defend host's immune responses; however, a clear association of co-colonization with a clinical outcome is lacking. METHODS: Children less than 5 years old who were admitted to hospital due to acute respiratory infections (ARI (n = 595 and healthy children (n = 350 were recruited. Carriage of pneumococcus was determined by culture and lytA PCR in the nasopharyngeal samples. Serotype/serogroup detection and its quantification were done by the nanofluidic real time PCR system. Spearman's correlation and logistic regression were used to examine a correlation of serotype/serogroup specific bacterial load with its prevalence and an association of co-colonization with ARI respectively. RESULTS: Serotype/serogroup specific bacterial load was correlated with its prevalence, both in ARI cases (Spearman's rho = 0.44, n = 186; P<0.0001 and healthy children (Spearman's rho = 0.41, n = 115; P<0.0001. The prevalence of multiple serotypes was more common in ARI cases than in healthy children (18.5% vs 7.1%; aOR 2.92, 95% CI: 1.27-6.71; P = 0.01. The dominant serotype in the co-colonization had a 2 log10 higher bacterial load than the subdominant serotype, both in ARI cases (P<0.001 and healthy children (P<0.05. CONCLUSIONS: High bacterial load in the nasopharynx may help transmit pneumococci among hosts, and increase the chance of successful acquisition and colonization. Co-colonization of multiple serotypes of pneumococci is linked with ARI, which infers the interactions of multiple serotypes may increase their pathogenicity; however, they may compete

  18. High-dimensional covariance estimation with high-dimensional data

    CERN Document Server

    Pourahmadi, Mohsen

    2013-01-01

    Methods for estimating sparse and large covariance matrices Covariance and correlation matrices play fundamental roles in every aspect of the analysis of multivariate data collected from a variety of fields including business and economics, health care, engineering, and environmental and physical sciences. High-Dimensional Covariance Estimation provides accessible and comprehensive coverage of the classical and modern approaches for estimating covariance matrices as well as their applications to the rapidly developing areas lying at the intersection of statistics and mac

  19. The Beta-MANOVA Ensemble with General Covariance

    OpenAIRE

    Dubbs, Alexander; Edelman, Alan

    2013-01-01

    We find the joint generalized singular value distribution and largest generalized singular value distributions of the $\\beta$-MANOVA ensemble with positive diagonal covariance, which is general. This has been done for the continuous $\\beta > 0$ case for identity covariance (in eigenvalue form), and by setting the covariance to $I$ in our model we get another version. For the diagonal covariance case, it has only been done for $\\beta = 1,2,4$ cases (real, complex, and quaternion matrix entries...

  20. Sparse covariance thresholding for high-dimensional variable selection

    OpenAIRE

    Daye, X. Jessie Jeng And Z. John

    2010-01-01

    In high-dimensions, many variable selection methods, such as the lasso, are often limited by excessive variability and rank deficiency of the sample covariance matrix. Covariance sparsity is a natural phenomenon in high-dimensional applications, such as microarray analysis, image processing, etc., in which a large number of predictors are independent or weakly correlated. In this paper, we propose the covariance-thresholded lasso, a new class of regression methods that can utilize covariance ...

  1. Analytical Solution of Covariance Evolution for Regular LDPC Codes

    OpenAIRE

    Nozaki, Takayuki; Kasai, Kenta; Sakaniwa, Kohichi

    2009-01-01

    The covariance evolution is a system of differential equations with respect to the covariance of the number of edges connecting to the nodes of each residual degree. Solving the covariance evolution, we can derive distributions of the number of check nodes of residual degree 1, which helps us to estimate the block error probability for finite-length LDPC code. Amraoui et al.\\ resorted to numerical computations to solve the covariance evolution. In this paper, we give the analytical solution o...

  2. How covariant is the galaxy luminosity function?

    CERN Document Server

    Smith, Robert E

    2012-01-01

    We investigate the error properties of certain galaxy luminosity function (GLF) estimators. Using a cluster expansion of the density field, we show how, for both volume and flux limited samples, the GLF estimates are covariant. The covariance matrix can be decomposed into three pieces: a diagonal term arising from Poisson noise; a sample variance term arising from large-scale structure in the survey volume; an occupancy covariance term arising due to galaxies of different luminosities inhabiting the same cluster. To evaluate the theory one needs: the mass function and bias of clusters, and the conditional luminosity function (CLF). We use a semi-analytic model (SAM) galaxy catalogue from the Millennium run N-body simulation and the CLF of Yang et al. (2003) to explore these effects. The GLF estimates from the SAM and the CLF qualitatively reproduce results from the 2dFGRS. We also measure the luminosity dependence of clustering in the SAM and find reasonable agreement with 2dFGRS results for bright galaxies. ...

  3. Covariance tracking: architecture optimizations for embedded systems

    Science.gov (United States)

    Romero, Andrés; Lacassagne, Lionel; Gouiffès, Michèle; Zahraee, Ali Hassan

    2014-12-01

    Covariance matching techniques have recently grown in interest due to their good performances for object retrieval, detection, and tracking. By mixing color and texture information in a compact representation, it can be applied to various kinds of objects (textured or not, rigid or not). Unfortunately, the original version requires heavy computations and is difficult to execute in real time on embedded systems. This article presents a review on different versions of the algorithm and its various applications; our aim is to describe the most crucial challenges and particularities that appeared when implementing and optimizing the covariance matching algorithm on a variety of desktop processors and on low-power processors suitable for embedded systems. An application of texture classification is used to compare different versions of the region descriptor. Then a comprehensive study is made to reach a higher level of performance on multi-core CPU architectures by comparing different ways to structure the information, using single instruction, multiple data (SIMD) instructions and advanced loop transformations. The execution time is reduced significantly on two dual-core CPU architectures for embedded computing: ARM Cortex-A9 and Cortex-A15 and Intel Penryn-M U9300 and Haswell-M 4650U. According to our experiments on covariance tracking, it is possible to reach a speedup greater than ×2 on both ARM and Intel architectures, when compared to the original algorithm, leading to real-time execution.

  4. Using Covariance Analysis to Assess Pointing Performance

    Science.gov (United States)

    Bayard, David; Kang, Bryan

    2009-01-01

    A Pointing Covariance Analysis Tool (PCAT) has been developed for evaluating the expected performance of the pointing control system for NASA s Space Interferometry Mission (SIM). The SIM pointing control system is very complex, consisting of multiple feedback and feedforward loops, and operating with multiple latencies and data rates. The SIM pointing problem is particularly challenging due to the effects of thermomechanical drifts in concert with the long camera exposures needed to image dim stars. Other pointing error sources include sensor noises, mechanical vibrations, and errors in the feedforward signals. PCAT models the effects of finite camera exposures and all other error sources using linear system elements. This allows the pointing analysis to be performed using linear covariance analysis. PCAT propagates the error covariance using a Lyapunov equation associated with time-varying discrete and continuous-time system matrices. Unlike Monte Carlo analysis, which could involve thousands of computational runs for a single assessment, the PCAT analysis performs the same assessment in a single run. This capability facilitates the analysis of parametric studies, design trades, and "what-if" scenarios for quickly evaluating and optimizing the control system architecture and design.

  5. Self-reported medication side effects in an older cohort living independently in the community - the Melbourne Longitudinal Study on Healthy Ageing (MELSHA: cross-sectional analysis of prevalence and risk factors

    Directory of Open Access Journals (Sweden)

    Browning Colette

    2010-06-01

    Full Text Available Abstract Background Medication side effects are an important cause of morbidity, mortality and costs in older people. The aim of our study was to examine prevalence and risk factors for self-reported medication side effects in an older cohort living independently in the community. Methods The Melbourne Longitudinal Study on Healthy Ageing (MELSHA, collected information on those aged 65 years or older living independently in the community and commenced in 1994. Data on medication side effects was collected from the baseline cohort (n = 1000 in face-to-face baseline interviews in 1994 and analysed as cross-sectional data. Risk factors examined were: socio-demographics, health status and medical conditions; medication use and health service factors. Analysis included univariate logistic regression to estimate unadjusted risk and multivariate logistic regression analysis to assess confounding and estimate adjusted risk. Results Self-reported medication side effects were reported by approximately 6.7% (67/1000 of the entire baseline MELSHA cohort, and by 8.5% (65/761 of those on medication. Identified risk factors were increased education level, co-morbidities and health service factors including recency of visiting the pharmacist, attending younger doctors, and their doctor's awareness of their medications. The greatest increase in risk for medication side effects was associated with liver problems and their doctor's awareness of their medications. Aging and gender were not risk factors. Conclusion Prevalence of self-reported medication side effects was comparable with that reported in adults attending General Practices in a primary care setting in Australia. The prevalence and identified risk factors provide further insight and opportunity to develop strategies to address the problem of medication side effects in older people living independently in the community setting.

  6. On the covariance matrices in the evaluated nuclear data

    International Nuclear Information System (INIS)

    The implications of the uncertainties of nuclear data on reactor calculations are shown. The concept of variance, covariance and correlation are expressed first by intuitive definitions and then through statistical theory. The format of the covariance data for ENDF/B is explained and the formulas to obtain the multigroup covariances are given. (Author)

  7. Earth Observation System Flight Dynamics System Covariance Realism

    Science.gov (United States)

    Zaidi, Waqar H.; Tracewell, David

    2016-01-01

    This presentation applies a covariance realism technique to the National Aeronautics and Space Administration (NASA) Earth Observation System (EOS) Aqua and Aura spacecraft based on inferential statistics. The technique consists of three parts: collection calculation of definitive state estimates through orbit determination, calculation of covariance realism test statistics at each covariance propagation point, and proper assessment of those test statistics.

  8. Conformally covariant operators and effective action in external gravitational field

    International Nuclear Information System (INIS)

    The n-dimensional expressions for the second order conformally covariant differentional operators acting on vector and tensor fields and for the fourth order conformally covariant operator acting on scalar fields are obtained. For the fourth order operator one-loop effective action is evaluated in four dimensions. The possibility of effective action evaluation for other conformally covariant operators is discussed

  9. The prevalence of SDQ-measured mental health problems at age 5-7 years and identification of predictors from birth to preschool age in a Danish birth cohort: the Copenhagen Child Cohort 2000

    DEFF Research Database (Denmark)

    Elberling, Hanne; Linneberg, Allan; Olsen, Else Marie;

    2010-01-01

    The objective of the study is to investigate the prevalence, distribution and predictors of mental health problems in 5-7-year-old Danish children in the general population. This study is a 5-7-year follow-up study of a birth cohort of 6,090 children, the Copenhagen Child Cohort 2000. The extende...

  10. The prevalence of SDQ-measured mental health problems at age 5-7 years and identification of predictors from birth to preschool age in a Danish birth cohort

    DEFF Research Database (Denmark)

    Elberling, Hanne; Linneberg, Allan; Olsen, Else Marie;

    2010-01-01

    The objective of the study is to investigate the prevalence, distribution and predictors of mental health problems in 5-7-year-old Danish children in the general population. This study is a 5-7-year follow-up study of a birth cohort of 6,090 children, the Copenhagen Child Cohort 2000. The extende...

  11. Prevalence and causes of visual impairment and blindness among adults with diabetes mellitus aged 40 years and older receiving treatment at government health facilities in the Mopani District, South Africa

    OpenAIRE

    R.G. Mabaso; O. A. Oduntan

    2014-01-01

    This article presents part of the findings of a study conducted to assess the prevalence and causes of visual impairment (VI) and blindness among adults with diabetes mellitus (DM) receiving treatment at the government health facilities in the Mopani District, South Africa.  This health facility-based cross-sectional study was conducted among 225 Black South African diabetics (161 females and 64 males) aged 40-90 years (mean= 61.50 ± 10.49) years at seven different health care facilities. All...

  12. Prevalence and severity of gingivitis in school students aged 6–11 years in Tafelah Governorate, South Jordan: results of the survey executed by National Woman’s Health Care Center

    OpenAIRE

    Rodan, Rania; Khlaifat, Feryal; Smadi, Leena; Azab, Reem; Abdalmohdi, Asma

    2015-01-01

    Background A cross-sectional census was conducted on 994 public school students aged 6-11 years living in 3 different parts of Tafeleh Governorate—South of Jordan, to determine the prevalence, and severity of gingivitis and to evaluate the oral hygiene habits among them as a part a survey executed by National Woman’s Health Care Center. All students were examined for gingival index (GI) and plaque index (PI), information about oral hygiene habits was recorded. Results Only 29.8 % had healthy ...

  13. Prevalence of anemia and deficiency of iron, folic acid, and zinc in children younger than 2 years of age who use the health services provided by the Mexican Social Security Institute

    Directory of Open Access Journals (Sweden)

    González-Unzaga Marco

    2007-11-01

    Full Text Available Abstract Background In Mexico, as in other developing countries, micronutrient deficiencies are common in infants between 6 and 24 months of age and are an important public health problem. The objective of this study was to determine the prevalence of anemia and of iron, folic acid, and zinc deficiencies in Mexican children under 2 years of age who use the health care services provided by the Mexican Institute for Social Security (IMSS. Methods A nationwide survey was conducted with a representative sample of children younger than 2 years of age, beneficiaries, and users of health care services provided by IMSS through its regular regimen (located in urban populations and its Oportunidades program (services offered in rural areas. A subsample of 4,955 clinically healthy children was studied to determine their micronutrient status. A venous blood sample was drawn to determine hemoglobin, serum ferritin, percent of transferrin saturation, zinc, and folic acid. Descriptive statistics include point estimates and 95% confidence intervals for the sample and projections for the larger population from which the sample was drawn. Results Twenty percent of children younger than 2 years of age had anemia, and 27.8% (rural to 32.6% (urban had iron deficiency; more than 50% of anemia was not associated with low ferritin concentrations. Iron stores were more depleted as age increased. Low serum zinc and folic acid deficiencies were 28% and 10%, respectively, in the urban areas, and 13% and 8%, respectively, in rural areas. The prevalence of simultaneous iron and zinc deficiencies was 9.2% and 2.7% in urban and rural areas. Children with anemia have higher percentages of folic acid deficiency than children with normal iron status. Conclusion Iron and zinc deficiencies constitute the principal micronutrient deficiencies in Mexican children younger than 2 years old who use the health care services provided by IMSS. Anemia not associated with low ferritin values

  14. Differences in structural covariance brain networks between behavioral variant frontotemporal dementia and Alzheimer's disease.

    Science.gov (United States)

    Hafkemeijer, Anne; Möller, Christiane; Dopper, Elise G P; Jiskoot, Lize C; van den Berg-Huysmans, Annette A; van Swieten, John C; van der Flier, Wiesje M; Vrenken, Hugo; Pijnenburg, Yolande A L; Barkhof, Frederik; Scheltens, Philip; van der Grond, Jeroen; Rombouts, Serge A R B

    2016-03-01

    Disease-specific patterns of gray matter atrophy in Alzheimer's disease (AD) and behavioral variant frontotemporal dementia (bvFTD) overlap with distinct structural covariance networks (SCNs) in cognitively healthy controls. This suggests that both types of dementia target specific structural networks. Here, we study SCNs in AD and bvFTD. We used structural magnetic resonance imaging data of 31 AD patients, 24 bvFTD patients, and 30 controls from two centers specialized in dementia. Ten SCNs were defined based on structural covariance of gray matter density using independent component analysis. We studied group differences in SCNs using F-tests, with Bonferroni corrected t-tests, adjusted for age, gender, and study center. Associations with cognitive performance were studied using linear regression analyses. Cross-sectional group differences were found in three SCNs (all P covariance gives valuable insights in the understanding of network pathology in dementia.

  15. Estimação de componentes de co-variância para pesos corporais do nascimento aos 365 dias de idade de bovinos Guzerá empregando-se modelos de regressão aleatória Estimates of covariance components for body weights from birth to 365 days of age in Guzera cattle, using random regression models

    Directory of Open Access Journals (Sweden)

    Luciele Cristina Pelicioni

    2009-01-01

    Full Text Available Um total de 19.770 pesos corporais de bovinos Guzerá, do nascimento aos 365 dias de idade, pertencentes ao banco de dados da Associação Brasileira dos Criadores de Zebu (ABCZ foi analisado com os objetivos de comparar diferentes estruturas de variâncias residuais, considerando 1, 18, 28 e 53 classes residuais e funções de variância de ordens quadrática a quíntica; e estimar funções de co-variância de diferentes ordens para os efeitos genético aditivo direto, genético materno, de ambiente permanente de animal e de mãe e parâmetros genéticos para os pesos corporais usando modelos de regressão aleatória. Os efeitos aleatórios foram modelados por regressões polinomiais em escala de Legendre com ordens variando de linear a quártica. Os modelos foram comparados pelo teste de razão de verossimilhança e pelos critérios de Informação de Akaike e de Informação Bayesiano de Schwarz. O modelo com 18 classes heterogêneas foi o que melhor se ajustou às variâncias residuais, de acordo com os testes estatísticos, porém, o modelo com função de variância de quinta ordem também mostrou-se apropriado. Os valores de herdabilidade direta estimados foram maiores que os encontrados na literatura, variando de 0,04 a 0,53, mas seguiram a mesma tendência dos estimados pelas análises unicaracterísticas. A seleção para peso em qualquer idade melhoraria o peso em todas as idades no intervalo estudado.A total of 19,770 body weight records of Guzera cattle, measured from birth to 365 days of age and supplied by the Brazilian Zebu Breeders Association, was analyzed with the following objectives of: 1 to compare different residual variances through step functions with 1, 18, 28 and 53 classes and through variance functions with orders ranging from two to five using ordinary polynomials and 2 to estimate covariance functions considering different orders for direct additive genetic effects, animal permanent environmental and maternal

  16. Self-Reported Cancer Prevalence among Hispanics in the US: Results from the Hispanic Community Health Study/Study of Latinos.

    Science.gov (United States)

    Penedo, Frank J; Yanez, Betina; Castañeda, Sheila F; Gallo, Linda; Wortman, Katy; Gouskova, Natalia; Simon, Melissa; Arguelles, William; Llabre, Maria; Sanchez-Johnsen, Lisa; Brintz, Carrie; Gonzalez, Patricia; Van Horn, Linda; Rademaker, Alfred W; Ramirez, Amelie G

    2016-01-01

    Cancer has surpassed heart disease as the leading cause of death among Hispanics in the U.S., yet data on cancer prevalence and risk factors in Hispanics in regard to ancestry remain scarce. This study sought to describe (a) the prevalence of cancer among Hispanics from four major U.S. metropolitan areas, (b) cancer prevalence across Hispanic ancestry, and (c) identify correlates of self-reported cancer prevalence. Participants were 16,415 individuals from the Hispanic Community Health Study/Study of Latinos (HCHS/SOL), who self-identified as Cuban, Dominican, Mexican, Puerto Rican, Central or South American. All data were collected at a single time point during the HCHS/SOL baseline clinic visit. The overall self-reported prevalence rate of cancer for the population was 4%. The rates varied by Hispanic ancestry group, with individuals of Cuban and Puerto Rican ancestry reporting the highest cancer prevalence. For the entire population, older age (OR = 1.47, p < .001, 95% CI, 1.26-1.71) and having health insurance (OR = 1.93, p < .001, 95% CI, 1.42-2.62) were all significantly associated with greater prevalence, whereas male sex was associated with lower prevalence (OR = 0.56, p < .01, 95% CI, .40-.79). Associations between study covariates and cancer prevalence also varied by Hispanic ancestry. Findings underscore the importance of sociodemographic factors and health insurance in relation to cancer prevalence for Hispanics and highlight variations in cancer prevalence across Hispanic ancestry groups. Characterizing differences in cancer prevalence rates and their correlates is critical to the development and implementation of effective prevention strategies across distinct Hispanic ancestry groups. PMID:26808047

  17. Disruption of structural covariance networks for language in autism is modulated by verbal ability.

    Science.gov (United States)

    Sharda, Megha; Khundrakpam, Budhachandra S; Evans, Alan C; Singh, Nandini C

    2016-03-01

    The presence of widespread speech and language deficits is a core feature of autism spectrum disorders (ASD). These impairments have often been attributed to altered connections between brain regions. Recent developments in anatomical correlation-based approaches to map structural covariance offer an effective way of studying such connections in vivo. In this study, we employed such a structural covariance network (SCN)-based approach to investigate the integrity of anatomical networks in fronto-temporal brain regions of twenty children with ASD compared to an age and gender-matched control group of twenty-two children. Our findings reflected large-scale disruption of inter and intrahemispheric covariance in left frontal SCNs in the ASD group compared to controls, but no differences in right fronto-temporal SCNs. Interhemispheric covariance in left-seeded networks was further found to be modulated by verbal ability of the participants irrespective of autism diagnosis, suggesting that language function might be related to the strength of interhemispheric structural covariance between frontal regions. Additionally, regional cortical thickening was observed in right frontal and left posterior regions, which was predicted by decreasing symptom severity and increasing verbal ability in ASD. These findings unify reports of regional differences in cortical morphology in ASD. They also suggest that reduced left hemisphere asymmetry and increased frontal growth may not only reflect neurodevelopmental aberrations but also compensatory mechanisms.

  18. Atrophy and structural covariance of the cholinergic basal forebrain in primary progressive aphasia.

    Science.gov (United States)

    Teipel, Stefan; Raiser, Theresa; Riedl, Lina; Riederer, Isabelle; Schroeter, Matthias L; Bisenius, Sandrine; Schneider, Anja; Kornhuber, Johannes; Fliessbach, Klaus; Spottke, Annika; Grothe, Michel J; Prudlo, Johannes; Kassubek, Jan; Ludolph, Albert; Landwehrmeyer, Bernhard; Straub, Sarah; Otto, Markus; Danek, Adrian

    2016-10-01

    Primary progressive aphasia (PPA) is characterized by profound destruction of cortical language areas. Anatomical studies suggest an involvement of cholinergic basal forebrain (BF) in PPA syndromes, particularly in the area of the nucleus subputaminalis (NSP). Here we aimed to determine the pattern of atrophy and structural covariance as a proxy of structural connectivity of BF nuclei in PPA variants. We studied 62 prospectively recruited cases with the clinical diagnosis of PPA and 31 healthy older control participants from the cohort study of the German consortium for frontotemporal lobar degeneration (FTLD). We determined cortical and BF atrophy based on high-resolution magnetic resonance imaging (MRI) scans. Patterns of structural covariance of BF with cortical regions were determined using voxel-based partial least square analysis. We found significant atrophy of total BF and BF subregions in PPA patients compared with controls [F(1, 82) = 20.2, p covariance analysis in healthy controls revealed associations of the BF nuclei, particularly the NSP, with left hemispheric predominant prefrontal, lateral temporal, and parietal cortical areas, including Broca's speech area (p covariance of the BF nuclei mostly with right but not with left hemispheric cortical areas (p covariance of the BF with left hemispheric cortical areas in healthy aging towards right hemispheric cortical areas in PPA, possibly reflecting a consequence of the profound and early destruction of cortical language areas in PPA.

  19. Covariant Quantum Gravity with Continuous Quantum Geometry I: Covariant Hamiltonian Framework

    CERN Document Server

    Pilc, Marián

    2016-01-01

    The first part of the series is devoted to the formulation of the Einstein-Cartan Theory within the covariant hamiltonian framework. In the first section the general multisymplectic approach is revised and the notion of the d-jet bundles is introduced. Since the whole Standard Model Lagrangian (including gravity) can be written as the functional of the forms, the structure of the d-jet bundles is more appropriate for the covariant hamiltonian analysis than the standard jet bundle approach. The definition of the local covariant Poisson bracket on the space of covariant observables is recalled. The main goal of the work is to show that the gauge group of the Einstein-Cartan theory is given by the semidirect product of the local Lorentz group and the group of spacetime diffeomorphisms. Vanishing of the integral generators of the gauge group is equivalent to equations of motion of the Einstein-Cartan theory and the local covariant algebra generated by Noether's currents is closed Lie algebra.

  20. Prevalence of COPD in Copenhagen

    DEFF Research Database (Denmark)

    Fabricius, Peder; Løkke, Anders; Marott, Jacob Louis;

    2011-01-01

    INTRODUCTION: COPD is a leading cause of death worldwide; however, prevalence estimates have varied considerably in previous studies. This study aimed to determine the prevalence and severity of COPD in Copenhagen using data from the 4th examination of The Copenhagen City Heart Study, to...... investigate the relationship between tobacco consumption and COPD, and to characterize the subjects with COPD with regard to BMI, dyspnoea, treatment with respiratory medication and co-morbidities. METHODS: 6236 people participated. All non-asthmatic participants aged 35 years or older with adequate lung...... function data were included for the final prevalence analyses (n = 5,299). COPD staging was done according to the GOLD criteria. RESULTS: The overall prevalence of COPD was 17.4%. The prevalence increased with age and was higher among males. 6.2% had mild COPD, 9.2% had moderate COPD, and 2.0% had severe...

  1. Shape covariation between the craniofacial complex and first molars in humans

    Science.gov (United States)

    Polychronis, Georgios; Halazonetis, Demetrios J

    2014-01-01

    The occurrence of mutual genetic loci in morphogenesis of the face and teeth implies shape covariation between these structures. However, teeth finalize their shape at an early age, whereas the face grows and is subjected to environmental influences for a prolonged period; it is therefore conceivable that covariation might modulate with age. Here we investigate the extent of this covariation in humans by measuring the 3D shape of the occlusal surface of the permanent first molars and the shape of the craniofacial complex from lateral radiographs, at two maturations stages. A sample of Greek subjects was divided into two groups (110 adult, 110 prepubertal) with equally distributed gender. The occlusal surfaces of the right first molars were 3D scanned from dental casts; 265 and 274 landmarks (including surface and curve semilandmarks) were digitized on the maxillary and mandibular molars, respectively. The corresponding lateral cephalometric radiographs were digitized with 71 landmarks. Geometric morphometric methods were used to assess shape variation and covariation. The vertical dimension of the craniofacial complex was the main parameter of shape variation, followed by anteroposterior deviations. The male craniofacial complex was larger (4.0–5.7%) and was characterized by a prominent chin and clockwise rotation of the cranial base (adult group only). Allometry was weak and statistically significant only when examined for the sample as a whole (percent variance explained: 2.1%, P = 0.0002). Covariation was statistically significant only between the lower first molar and the craniofacial complex (RV = 14.05%, P = 0.0099, and RV = 12.31%, P = 0.0162, for the prepubertal and adult groups, respectively). Subtle age-related covariation differences were noted, indicating that environmental factors may influence the pattern and strength of covariation. However, the main pattern was similar in both groups: a class III skeletal pattern (relative maxillary retrusion and

  2. Prevalence of oral health problems in U.S. adults, NHANES 1999–2004: exploring differences by age, education, and race/ethnicity

    OpenAIRE

    Kim, Jung Ki; Baker, Lindsey A.; Seirawan, Hazem; Crimmins, Eileen M.

    2012-01-01

    Using the National Health and Nutrition Examination Surveys (NHANES) 1999–2004, the authors examined age patterns in oral health indicators by race/ethnicity and socioeconomic status related to edentulism, presence of root caries, and periodontal disease. Our analysis included subjects who were non-Hispanic White, Mexican American, and African American over the age of 20, and who participated in the NHANES oral health examination. African Americans experienced more oral health problems at you...

  3. Seasonality of suicides: environmental, sociological and biological covariations.

    Science.gov (United States)

    Souêtre, E; Salvati, E; Belugou, J L; Douillet, P; Braccini, T; Darcourt, G

    1987-01-01

    The monthly rates of completed suicides in France from 1978 until 1982 were analyzed. The seasonal variations of environmental (daylight and sunlight durations, mean temperature, geomagnetism), sociological (unemployment, deaths of all causes, birth and conception rates), and biological (melatonin, cortisol and serotonin circannual rhythms) factors were compared to the seasonal patterns of suicides. A clear seasonal variation (with peaks in May and September) in suicidal behavior was detected. These patterns tended to differ as a function of age (bimodal in young, unimodal in old people). The component analysis clearly pointed out that seasonal patterns of suicides may be considered as the sum of two components, unimodal and bimodal. Almost similar covariations were found between the main seasonal (unimodal) component of suicides and environmental (daylight duration and mean monthly temperature) or sociological factors whereas the secondary component was more correlated to variations in environmental factors and, to some extent, to biological parameters. PMID:2960714

  4. Quantum energy inequalities and local covariance II: categorical formulation

    Science.gov (United States)

    Fewster, Christopher J.

    2007-11-01

    We formulate quantum energy inequalities (QEIs) in the framework of locally covariant quantum field theory developed by Brunetti, Fredenhagen and Verch, which is based on notions taken from category theory. This leads to a new viewpoint on the QEIs, and also to the identification of a new structural property of locally covariant quantum field theory, which we call local physical equivalence. Covariant formulations of the numerical range and spectrum of locally covariant fields are given and investigated, and a new algebra of fields is identified, in which fields are treated independently of their realisation on particular spacetimes and manifestly covariant versions of the functional calculus may be formulated.

  5. Investigation of the prevalence of temporomandibular disorders in 352 aged edentulous individuals%352名无牙颌老年人颞下颌关节紊乱病调查

    Institute of Scientific and Technical Information of China (English)

    史琦; 王燕一

    2012-01-01

    目的 对无牙颌老年人颞下颌关节紊乱病( temporomandibular disorders,TMD)的情况进行调查并初步探讨相关的危险因素.方法 352名北京市无牙颌老年人参加本次调查,男性198人,女性154人.根据Helkimo指数设计调查表,由专业培训人员对受试者进行颞下颌关节相关症状和体征的检查并记录.根据性别以及是否进行全口义齿修复分别统计分析.结果本组人群TMD查体阳性率为43.2%(152/352),其中阳性体征以关节弹响多见,占34.1%( 120/352);下颌运动偏斜次之,占18.2%(64/352),关节区及咀嚼肌触痛则发生较少,下颌运动痛最少.男性TMD查体阳性率为36.9%(73/198),女性为51.3%(79/154),两者差异有统计学意义(P =0.0067 <0.01);行全口义齿修复的无牙颌老人TMD查体阳性率为38.6%(91/236),未修复者TMD查体阳性率为52.6%(61/116),两者差异有统计学意义(P =0.0125 <0.05),其OR值为1.767(1.130~2.763).结论 性别因素及不良咬合均可能是影响老年无牙颌者TMD患病率的危险因素.%Objective To study the prevalence of temporomandibular disorders(TMD) in 352 aged edentulous individuals in Beijing area and to analyze the correlative risk factors.Methods Three hundred and fifty-two aged edentulous subjects were included in the study ( 198 males and 154 females).The adopted questionnaire was designed according to Helkimo index,and the subjects were examined by the same examiner who would record every result as well.Results The prevalence of TMD's clinical positive signs in the edentulous subjects was 43.2% ( 152/352 ),among which temporomandibular joint ( TMJ ) noise [34.1% (120/352)] was the highest prevalent sign while TMJ pain on movemert was the lowest.The prevalence of mandibular movement deviation [ 18.2% (64/352)] fitted in between.The prevalence of TMD's clinical positive signs of male individuals was 36.9% (73/198),and the female was 51.3% (79/154).There was a significant

  6. [Smoking prevalence in Kocaeli].

    Science.gov (United States)

    Bariş, Serap Argun; Yildiz, Füsun; Başyiğit, Ilknur; Boyaci, Haşim

    2011-01-01

    A questionnaire was performed in order to determine smoking prevalence in the target population just before the initiation of a social responsibility project which is aimed to increase the smoking cessation rates in Kocaeli. The sample selection was made based on population numbers in 12 town of Kocaeli city and smoking habits of population over the age of 18 were evaluated by a questionnaire survey by phone. There was 2721 person included in the study. The overall prevalence of active smokers was 32.3% (n= 902) and ex-smokers was 21.5% (n= 587). There was no statistical significance of smoking prevalence among towns except the lower smoking rates in Gebze (25.7%). The percentage of the current smokers was 42.5% in male population which was significantly higher than females (21.8%). The highest smoking prevalence was found between the ages of 35-44 (41.2%) while the lowest prevalence was observed in the subjects older than 55 years (19.8%). The mean age for smoking initiation was 19 years (17-20) and daily cigarette consumption was 17 sticks. Previous attempts for quitting smoking were found in 67.7% of current smokers. The mean number of smoking cessation attempts was 3 times and the mean duration of cessation was 5 months. The most common reason for smoking cessation was health issues. Eighty percent of cases harnessed their willpower to stop smoking while only 5% of them received medical treatment. It is suggested that determination of demographic features of the smokers might constitute a corner stone for smoking cessation projects.

  7. [Smoking prevalence in Kocaeli].

    Science.gov (United States)

    Bariş, Serap Argun; Yildiz, Füsun; Başyiğit, Ilknur; Boyaci, Haşim

    2011-01-01

    A questionnaire was performed in order to determine smoking prevalence in the target population just before the initiation of a social responsibility project which is aimed to increase the smoking cessation rates in Kocaeli. The sample selection was made based on population numbers in 12 town of Kocaeli city and smoking habits of population over the age of 18 were evaluated by a questionnaire survey by phone. There was 2721 person included in the study. The overall prevalence of active smokers was 32.3% (n= 902) and ex-smokers was 21.5% (n= 587). There was no statistical significance of smoking prevalence among towns except the lower smoking rates in Gebze (25.7%). The percentage of the current smokers was 42.5% in male population which was significantly higher than females (21.8%). The highest smoking prevalence was found between the ages of 35-44 (41.2%) while the lowest prevalence was observed in the subjects older than 55 years (19.8%). The mean age for smoking initiation was 19 years (17-20) and daily cigarette consumption was 17 sticks. Previous attempts for quitting smoking were found in 67.7% of current smokers. The mean number of smoking cessation attempts was 3 times and the mean duration of cessation was 5 months. The most common reason for smoking cessation was health issues. Eighty percent of cases harnessed their willpower to stop smoking while only 5% of them received medical treatment. It is suggested that determination of demographic features of the smokers might constitute a corner stone for smoking cessation projects. PMID:21740388

  8. Age and Gender Specific Trends of Prevalence of Metabolic Syndrome%代谢综合征患病率随性别和年龄的变化趋势

    Institute of Scientific and Technical Information of China (English)

    徐旭; 刘耘; 梁国威

    2011-01-01

    目的 探讨代谢综合征患病率随性别和年龄的变化趋势.方法 对2006年1~12月和2009年1~12月笔者医院的健康体检人群进行回顾性调查.男性:2006年1619例,2009年2202例;女性:2006年418例,2009年636例.MS诊断标准采用NCEP-ATPⅢ的中国人修订标准.结果 男性2009年的MS患病率(41.2% vs 36.6%,P=0.003)较2006年显著增加了4 6%;女性2009年MS患病率(33.2% vs 36.1%,P>0.05)较2006年降低了2.9%.年龄分层显示,男性在44岁以下MS患病率有下降趋势,45岁后各年龄组皆呈增加趋势,特别是45~64岁年龄段MS患病率显著增加(P<0.05);女性年龄小于64岁MS患病率呈降低趋势,65岁后呈增加趋势.2006~2009年MS各危险因子变化率比较显示,2009年男性WC、HDL-C、FPG阳性例数明显增加(P<0.05);女性TG阳性例数明显减少(P<0.05).结论 2006~2009年北京某公司MS患病率变化趋势呈现明显的性别和年龄差异.男性45~64岁和女性65岁后人群是MS患病的重点防治人群.%Objective To investigate the age and gender specific trends of prevalence of metaholic syndrome ( MS) . Methods A retrospective cross - sectional study was performed from 2006 to 2009. 1619 men and 418 women in 2006. 2202 men and 636 women in 2009 , respectively. were recruited from our hospital. MS was defined according to the National Cholesterol Education Program - Adult Treatment Panel Ⅲ ( NCEP - ATP Ⅲ ) criteria modified for Chinese subjects. Results Compared with subjects in 2006, the trend of prevalence of MS (41 . 2% vs 36. 6% , P = 0. 003) increased 4. 6% in men, and decreased 2. 9% in women (33. 2% vs 36. 1% . P > 0. 05) . respectively. They were stratified by age of interval 10 years old as a subgroup. In men, the trend of prevalence of MS decreased in subjects below 44 years old. and increased in subjects above 45 years old, especially significantly increased in subjects in the intervals of 45 -64 years old (P <0. 05). In women, the trend of

  9. Radiation exposure, young age, and female gender are associated with high prevalence of RET/PTC1 and RET/PTC3 in papillary thyroid cancer: a meta-analysis

    Science.gov (United States)

    Su, Xuan; Li, Zhaoqu; He, Caiyun; Chen, Weichao; Fu, Xiaoyan; Yang, Ankui

    2016-01-01

    Background RET/PTC rearrangements have been identified as a specific genetic event in papillary thyroid cancer (PTC). We conducted this meta-analysis to identify an enriched population who were more likely to occur RET/PTC fusion genes. Methods All relevant studies in the PubMed, Web of Science, and Embase databases were searched up to June 2015. The studies found were screened according to our inclusion and exclusion criteria. All analyses were performed using STATA software. Results Eventually, 38 eligible studies comprising 2395 participants were included. Overall analysis indicated that radiation exposure contributed to increased RET/PTC risk (OR = 2.82; 95%CI: 1.38–5.78, P = 0.005). Stratified analysis according to RET/PTC subtype and geographical area showed that this association was restricted to the RET/PTC3 subtype (OR = 8.30, 95%CI: 4.32–15.96, P < 0.001) in the Western population. In addition, age < 18 years, i.e., young age, was associated with higher prevalence of RET/PTC3 (OR = 2.03, 95%CI: 1.14–3.62, P = 0.017), especially in the radiation-exposure subpopulation (OR = 2.35, 95%CI: 1.01–5.49, P = 0.048). The association between female gender and RET/PTC1 risk was more significant in the PTC patients without radiation exposure (OR = 1.69, 95%CI: 1.04–2.74, P = 0.034). Conclusion Both radiation exposure and young age are associated with increased risk of RET/PTC3 and that female gender is associated with higher prevalence of RET/PTC1 in the subpopulation without radiation exposure. The RET/PTC status in combination with radiation exposure, age, and sex should be considered in the differential diagnosis of suspicious PTC. PMID:26918339

  10. The prevalence, patterns and predictors of diabetic peripheral neuropathy in a developing country

    Directory of Open Access Journals (Sweden)

    Katulanda Prasad

    2012-05-01

    Full Text Available Abstract Prevalence of diabetes mellitus (DM has reached epidemic proportions in Sri Lanka. Presently there are studies on the community prevalence of distal peripheral neuropathy (DPN in Sri Lanka. We describe prevalence, patterns and predictors of DPN in patients with DM in Sri Lanka. Data were collected as part of a national study on DM. In new cases DPN was assessed using the Diabetic-Neuropathy-Symptom (DNS score, while in those with established diabetes both DNS and Toronto-Clinical-Scoring-System (TCSS were used. A binary logistic-regression analysis was performed with ‘presence of DPN’ as the dichomatous dependent variable and other independent co-variants. The study included 528 diabetic patients (191-new cases, with a mean age of 55.0 ± 12.4 years and 37.3% were males, while 18% were from urban areas. Prevalence of DPN according to DNS score among all patients, patients with already established diabetes and newly diagnosed patients were 48.1%, 59.1% and 28.8% respectively. Prevalence of DPN in those with established DM as assessed by TCSS was 24% and the majority had mild DPN (16.6%. The remainder of the abstract is based on subjects with established DM. The prevalence of DPN in males and female was 20.0% and 26.4% respectively. The mean age of those with and without DPN was 62.1 ± 10.8 and 55.1 ± 10.8 years respectively (p 

  11. MATXTST, Basic Operations for Covariance Matrices

    International Nuclear Information System (INIS)

    1 - Description of program or function: MATXTST and MATXTST1 perform the following operations for a covariance matrix: - test for singularity; - test for positive definiteness; - compute the inverse if the matrix is non-singular; - compute the determinant; - determine the number of positive, negative, and zero eigenvalues; - examine all possible 3 X 3 cross correlations within a sub-matrix corresponding to a leading principal minor which is non-positive definite. While the two programs utilize the same input, the calculational procedures employed are somewhat different and their functions are complementary. The available input options include: i) the full covariance matrix, ii) the basic variables plus the relative covariance matrix, or iii) uncertainties in the basic variables plus the correlation matrix. 2 - Method of solution: MATXTST employs LINPACK subroutines SPOFA and SPODI to test for positive definiteness and to perform further optional calculations. Subroutine SPOFA factors a symmetric matrix M using the Cholesky algorithm to determine the elements of a matrix R which satisfies the relation M=R'R, where R' is the transposed matrix of R. Each leading principal minor of M is tested until the first one is found which is not positive definite. MATXTST1 uses LINPACK subroutines SSICO, SSIFA, and SSIDI to estimate whether the matrix is near to singularity or not (SSICO), and to perform the matrix diagonalization process (SSIFA). The algorithm used in SSIFA is generalization of the Method of Lagrange Reduction. SSIDI is used to compute the determinant and inertia of the matrix. 3 - Restrictions on the complexity of the problem: Matrices of sizes up to 50 X 50 elements can be treated by present versions of the programs

  12. PREVALENCE OF REFRACTIVE ERROR AND OTHER OCULAR MORBIDITIES AND FOLLOW-UP STUDY ON COMPLIANCE TO SPECTACLES USE AMONG SCHOOL GOING CHILDREN AGED 9-16 YEARS IN SELECTED VILLAGE OF HASSAN

    Directory of Open Access Journals (Sweden)

    Sumana

    2015-11-01

    Full Text Available BACKGROUND Uncorrected refractive errors are the most common cause of visual impairment in school children in India. AIMS AND OBJECTIVES To find out prevalence and risk factors of refractive error. To identify other ocular morbidities and to assess the compliance to spectacle use. SETTINGS AND DESIGN A cross-sectional study was carried out in school going children of age group 9-16 yrs. in Salagame, Hassan. METHODS AND MATERIALS All school going children were examined using Snellen’s chart at 6m distance, height and weight are measured using appropriate scale, external appearance of eyes examined using torch, colour vision examined by Ishihara chart. Refractive error, parental refractive error, close reading and TV watching, sociodemographic profile etc., were assessed in all children by sending questionnaire to parents. After six months, school was revisited without prior notice to assess how many were actually wearing spectacles. STATISTICAL ANALYSIS USED Statistical analysis was done using Microsoft Excel for data entry and Epi Info software for analysis. Descriptive statistics to summarize and Chi square test to correlate risk factors and refractive error. RESULTS Among 362 students examined, 179 were boys and 183 were girls. Prevalence of refractive error was 8.3%. Age, Close TV watching and parental use of spectacles were found to be significant in the prevalence of refractive error in school going children. Only 38% children were wearing spectacles at the time of followup. CONCLUSION There is the need for periodic screening and followup of students studying in Government schools. History of close TV watching by parents is an important clue for the presence of refractive errors.

  13. Prevalencia de la incontinencia urinaria en personas mayores de 64 años en Galicia Prevalence of urinary incontinence in the population aged more than 64 years in Galicia, Spain

    Directory of Open Access Journals (Sweden)

    J.M. Dios-Diz

    2003-10-01

    Full Text Available Objetivo: Conocer la prevalencia de la incontinencia urinaria en Galicia en personas mayores de 64 años. Métodos: Se trata de un estudio descriptivo, basado en una encuesta personal a cada una de las personas de la muestra de la población diana. Ésta se obtuvo mediante un muestreo aleatorio estratificado en ámbito urbano, semiurbano y rural, en el conjunto de la comunidad de Galicia y, posteriormente, extrayendo una muestra al azar de la base de datos de la Tarjeta Individual Sanitaria de las localidades preseleccionadas. En total se obtuvieron 350 encuestas en 12 puntos de muestreo. Resultados: La prevalencia de la incontinencia urinaria en Galicia en el año 2002 es del 35,1% (intervalo de confianza del 95%, 31-38; 15-28 en varones y 38-51 en mujeres. Conclusiones: Uno de cada tres gallegos mayores de 64 años presenta incontinencia urinaria, siendo la prevalencia casi el doble en las mujeres.Objective: To determine the prevalence of urinary incontinence in the Galician population aged more than 64 years. Methods: We performed a descriptive study, based on a personal interview with each individual from a sample of the target population. The sample was obtained through random sampling stratified into urban, semi-urban and rural of the Autonomous Community of Galicia. Subsequently, a random sample was extracted from the database of the individual health cards of selected localities. A total of 350 interviews in 12 sampling locations were performed. Results: The prevalence of urinary incontinence in Galicia in 2002 was 35.14% (95% CI: 31-38%, 15-28 for men and 38-51% for women. Conclusions: One out of three Galicians aged more than 64 years presents urinary incontinence. The prevalence is almost double in women.

  14. Spatiotemporal noise covariance estimation from limited empirical magnetoencephalographic data

    Energy Technology Data Exchange (ETDEWEB)

    Jun, Sung C [MS-D454, Applied Modern Physics Group, Los Alamos National Laboratory, Los Alamos, NM 87545 (United States); Plis, Sergey M [MS-D454, Applied Modern Physics Group, Los Alamos National Laboratory, Los Alamos, NM 87545 (United States); Ranken, Doug M [MS-D454, Applied Modern Physics Group, Los Alamos National Laboratory, Los Alamos, NM 87545 (United States); Schmidt, David M [MS-D454, Applied Modern Physics Group, Los Alamos National Laboratory, Los Alamos, NM 87545 (United States)

    2006-11-07

    The performance of parametric magnetoencephalography (MEG) and electroencephalography (EEG) source localization approaches can be degraded by the use of poor background noise covariance estimates. In general, estimation of the noise covariance for spatiotemporal analysis is difficult mainly due to the limited noise information available. Furthermore, its estimation requires a large amount of storage and a one-time but very large (and sometimes intractable) calculation or its inverse. To overcome these difficulties, noise covariance models consisting of one pair or a sum of multi-pairs of Kronecker products of spatial covariance and temporal covariance have been proposed. However, these approaches cannot be applied when the noise information is very limited, i.e., the amount of noise information is less than the degrees of freedom of the noise covariance models. A common example of this is when only averaged noise data are available for a limited prestimulus region (typically at most a few hundred milliseconds duration). For such cases, a diagonal spatiotemporal noise covariance model consisting of sensor variances with no spatial or temporal correlation has been the common choice for spatiotemporal analysis. In this work, we propose a different noise covariance model which consists of diagonal spatial noise covariance and Toeplitz temporal noise covariance. It can easily be estimated from limited noise information, and no time-consuming optimization and data-processing are required. Thus, it can be used as an alternative choice when one-pair or multi-pair noise covariance models cannot be estimated due to lack of noise information. To verify its capability we used Bayesian inference dipole analysis and a number of simulated and empirical datasets. We compared this covariance model with other existing covariance models such as conventional diagonal covariance, one-pair and multi-pair noise covariance models, when noise information is sufficient to estimate them. We

  15. SO(2,1) Covariant IIB Superalgebra

    OpenAIRE

    Abe, Mitsuko; Hatsuda, Machiko; Kamimura, Kiyoshi; Tokunaga, Takashi

    1999-01-01

    We propose a type IIB super-Poincare algebra with SO(2,1) covariant central extension. Together with SO(2,1) and SO(9,1) generators, a SO(2,1) triplet (momenta), a Majorana-spinor doublet (supercharges) and a Rarita-Schwinger central charge generate a group, G. We consider a coset G/H where H=(SO(2) x Lorentz), and the SL(2,R) 2-form doublet is obtained by the coset construction. It is shown that U(1) connections, whose strengths are associated with 2-forms, are recognized as coordinates of t...

  16. Radiative Transfer in Special Relativity: Covariance

    CERN Document Server

    Duque, Mauricio; Duque, Carlos

    2007-01-01

    The purpose is to introduce in a clear and direct way the students of undergraduate courses in physics and/or astronomy to the subject of radiative transfer. A pedagogical revision is made in order to obtain the radiative transfer equation, its restrictions and the different types of interactions present between the radiation and the matter. Because in the classical literature about radiative transfer the covariance is not fully developed, we show in an explicit manner detail calculations and then we discuss the relativistic effects.

  17. Minimal covariant observables identifying all pure states

    Energy Technology Data Exchange (ETDEWEB)

    Carmeli, Claudio, E-mail: claudio.carmeli@gmail.com [D.I.M.E., Università di Genova, Via Cadorna 2, I-17100 Savona (Italy); I.N.F.N., Sezione di Genova, Via Dodecaneso 33, I-16146 Genova (Italy); Heinosaari, Teiko, E-mail: teiko.heinosaari@utu.fi [Turku Centre for Quantum Physics, Department of Physics and Astronomy, University of Turku (Finland); Toigo, Alessandro, E-mail: alessandro.toigo@polimi.it [Dipartimento di Matematica, Politecnico di Milano, Piazza Leonardo da Vinci 32, I-20133 Milano (Italy); I.N.F.N., Sezione di Milano, Via Celoria 16, I-20133 Milano (Italy)

    2013-09-02

    It has been recently shown by Heinosaari, Mazzarella and Wolf (2013) [1] that an observable that identifies all pure states of a d-dimensional quantum system has minimally 4d−4 outcomes or slightly less (the exact number depending on d). However, no simple construction of this type of minimal observable is known. We investigate covariant observables that identify all pure states and have minimal number of outcomes. It is shown that the existence of this kind of observables depends on the dimension of the Hilbert space.

  18. Linear Covariance Analysis and Epoch State Estimators

    Science.gov (United States)

    Markley, F. Landis; Carpenter, J. Russell

    2014-01-01

    This paper extends in two directions the results of prior work on generalized linear covariance analysis of both batch least-squares and sequential estimators. The first is an improved treatment of process noise in the batch, or epoch state, estimator with an epoch time that may be later than some or all of the measurements in the batch. The second is to account for process noise in specifying the gains in the epoch state estimator. We establish the conditions under which the latter estimator is equivalent to the Kalman filter.

  19. Non-evaluation applications for covariance matrices

    Energy Technology Data Exchange (ETDEWEB)

    Smith, D.L.

    1982-05-01

    The possibility for application of covariance matrix techniques to a variety of common research problems other than formal data evaluation are demonstrated by means of several examples. These examples deal with such matters as fitting spectral data, deriving uncertainty estimates for results calculated from experimental data, obtaining the best values for plurally-measured quantities, and methods for analysis of cross section errors based on properties of the experiment. The examples deal with realistic situations encountered in the laboratory, and they are treated in sufficient detail to enable a careful reader to extrapolate the methods to related problems.

  20. State-specific prevalence of current cigarette smoking and smokeless tobacco use among adults aged ≥18 years - United States, 2011-2013.

    Science.gov (United States)

    Nguyen, Kimberly; Marshall, LaTisha; Hu, Sean; Neff, Linda

    2015-05-22

    Cigarette smoking and the use of smokeless tobacco both cause substantial morbidity and premature mortality. The concurrent use of these products might increase dependence and the risk for tobacco-related disease and death. State-specific estimates of prevalence and relative percent change in current cigarette smoking, smokeless tobacco use, and concurrent cigarette smoking and smokeless tobacco use among U.S. adults during 2011-2013, developed using data from the Behavioral Risk Factor Surveillance System (BRFSS), indicate statistically significant (padvertising and promotion, controlling access to tobacco products, and promoting cessation assistance for smokers to quit, as well as continuing and implementing mass media campaigns that contain graphic anti-smoking ads, such as the Tips from Former Smokers (TIPS) campaign. PMID:25996096