WorldWideScience

Sample records for age determination by skeleton

  1. Microscopic age determination of human skeletons including an unknown but calculable variable

    DEFF Research Database (Denmark)

    Wallin, Johan Albert; Tkocz, Izabella; Kristensen, Gustav

    1994-01-01

    Histomorphometric semi-automatic image analysis of cross-sections of 101 femoral diaphyseal bone sections were performed to reconsider to what degree osteon remodelling in the outer cortex is affected by age. The data were analysed statistically using the generalized least squares method. The mod...... impression of higher precision of age determination. The present study demonstrates that determination of age at death through microscopic bone morphometry is considerably less precise than generally stated in the literature....

  2. Rapid determination of fluorine in coral skeletons by non-destructive neutron activation analysis using 20F

    International Nuclear Information System (INIS)

    A rapid non-destructive technique has been proposed for the determination of fluorine in coral skeletons by thermal neutron activation analysis, using the short half-life 20F nuclide (11.0 s). About 0.2-0.5 g samples were irradiated for 10 seconds in a Triga Mark II Reactor. Soon after the irradiation (25-35 s), measurements of γ-rays were performed with each sample and standard. The method has the drawback of low sensitivity (∼20 ppm of F), and the manual operation employed in the cooling step could lead to less precise measurements. Fluorine in coral standards was determined within ∼8% of analytical precision. The result obtained for the dolomite standard was fairly consistent with literature values, but those for the limestone standard showed to be considerably higher than the reported values. The present method was applied for the determination of fluorine in modern corals from Khang Khao Island, Thailand and Okinawa, Japan. Two core samples of an ancient reef from Funafuti Atoll were measured for fluorine to compare with modern samples. In order to understand the environmental media in which coral grew, the partition of fluorine between seawater and coral skeletons is also discussed. (author)

  3. Iterating skeletons:structured parallelism by composition

    OpenAIRE

    Dieterle, Mischa; Horstmeyer, Thomas; Berthold, Jost; Loogen, Rita

    2012-01-01

    Skeleton-based programming is an area of increasing relevance with upcoming highly parallel hardware, since it substantially facilitates parallel programming and separates concerns. When parallel algorithms expressed by skeletons involve iterations – applying the same algorithm repeatedly to successively improving data, the repeated instantiation of a skeleton incurs a certain overhead that could be saved by reusing existing processes, threads and communication structures. This is especially ...

  4. Microarchitectural changes in the aging skeleton.

    Science.gov (United States)

    Gabet, Yankel; Bab, Itai

    2011-12-01

    The age-related reduction in bone mass is disproportionally related to skeletal weakening, suggesting that microarchitectural changes are also important determinants of bone quality. The study of cortical and trabecular microstructure, which for many years was mainly based on two-dimensional histologic and scanning electron microscopy imaging, gained a tremendous momentum in the last decade and a half, due to the introduction of microcomputed tomography (μCT). This technology provides highly accurate qualitative and quantitative analyses based on three-dimensional images at micrometer resolution, which combined with finite elemental analysis predicts the biomechanical implications of microstructural changes. Global μCT analyses of trabecular bone have repeatedly suggested that the main age-related change in this compartment is a decrease in trabecular number with unaltered, or even increased, trabecular thickness. However, we show here that this may result from a bias whereby thick trabeculae near the cortex and the early clearance of thin struts mask authentic trabecular thinning. The main cortical age-related change is increased porosity due to negatively balanced osteonal remodeling and expansion of Haversian canals, which occasionally merge with endosteal and periosteal resorption bays, thus leading to rapid cortical thinning and cortical weakening. The recent emergence of CT systems with submicrometer resolution provides novel information on the age-related decrease in osteocyte lacunar density and related micropetrosis, the result of lacunar hypermineralization. Last but not least, the use of the submicrometer CT systems confirmed the occurrence of microcracks in the skeletal mineralized matrix and vastly advanced their morphologic characterization and mode of initiation and propagation. PMID:21901426

  5. Refining image segmentation by polygon skeletonization

    Science.gov (United States)

    Clarke, Keith C.

    1987-01-01

    A skeletonization algorithm was encoded and applied to a test data set of land-use polygons taken from a USGS digital land use dataset at 1:250,000. The distance transform produced by this method was instrumental in the description of the shape, size, and level of generalization of the outlines of the polygons. A comparison of the topology of skeletons for forested wetlands and lakes indicated that some distinction based solely upon the shape properties of the areas is possible, and may be of use in an intelligent automated land cover classification system.

  6. Evidence of authentic DNA from Danish Viking Age skeletons untouched by humans for 1,000 years.

    Directory of Open Access Journals (Sweden)

    Linea Melchior

    Full Text Available BACKGROUND: Given the relative abundance of modern human DNA and the inherent impossibility for incontestable proof of authenticity, results obtained on ancient human DNA have often been questioned. The widely accepted rules regarding ancient DNA work mainly affect laboratory procedures, however, pre-laboratory contamination occurring during excavation and archaeological-/anthropological handling of human remains as well as rapid degradation of authentic DNA after excavation are major obstacles. METHODOLOGY/PRINCIPAL FINDINGS: We avoided some of these obstacles by analyzing DNA from ten Viking Age subjects that at the time of sampling were untouched by humans for 1,000 years. We removed teeth from the subjects prior to handling by archaeologists and anthropologists using protective equipment. An additional tooth was removed after standard archaeological and anthropological handling. All pre-PCR work was carried out in a "clean- laboratory" dedicated solely to ancient DNA work. Mitochondrial DNA was extracted and overlapping fragments spanning the HVR-1 region as well as diagnostic sites in the coding region were PCR amplified, cloned and sequenced. Consistent results were obtained with the "unhandled" teeth and there was no indication of contamination, while the latter was the case with half of the "handled" teeth. The results allowed the unequivocal assignment of a specific haplotype to each of the subjects, all haplotypes being compatible in their character states with a phylogenetic tree drawn from present day European populations. Several of the haplotypes are either infrequent or have not been observed in modern Scandinavians. The observation of haplogroup I in the present study (<2% in modern Scandinavians supports our previous findings of a pronounced frequency of this haplogroup in Viking and Iron Age Danes. CONCLUSION: The present work provides further evidence that retrieval of ancient human DNA is a possible task provided adequate

  7. Estimation of sex and age of ''virtual skeletons''-a feasibility study

    International Nuclear Information System (INIS)

    This article presents a feasibility study with the objective of investigating the potential of multi-detector computed tomography (MDCT) to estimate the bone age and sex of deceased persons. To obtain virtual skeletons, the bodies of 22 deceased persons with known age at death were scanned by MDCT using a special protocol that consisted of high-resolution imaging of the skull, shoulder girdle (including the upper half of the humeri), the symphysis pubis and the upper halves of the femora. Bone and soft-tissue reconstructions were performed in two and three dimensions. The resulting data were investigated by three anthropologists with different professional experience. Sex was determined by investigating three-dimensional models of the skull and pelvis. As a basic orientation for the age estimation, the complex method according to Nemeskeri and co-workers was applied. The final estimation was effected using additional parameters like the state of dentition, degeneration of the spine, etc., which where chosen individually by the three observers according to their experience. The results of the study show that the estimation of sex and age is possible by the use of MDCT. Virtual skeletons present an ideal collection for anthropological studies, because they are obtained in a non-invasive way and can be investigated ad infinitum. (orig.)

  8. Studies on the structure of peat humic acid (II). Study on the determination of the aromatic skeletons in peat humic acid by zinc-dust distillation

    Energy Technology Data Exchange (ETDEWEB)

    Oka, H.; Sasaki, M.

    1979-01-01

    In order to determine aromatic skeletons in the chemical structure of peat humic acid, zinc-dust distillation was carried out at 500 C for 2 hours in a stream of hydrogen, and the results compared to those from other substances such as phtholic acid, cumarin, naphthoquinone and ..cap alpha..-lactone. Subsequently, methods for the identification and semi-quantitative determination of polycyclic aromatic hydrocarbons were applied. The total yield of polycyclic hydrocarbon having anthracene, pyrene and perylene rings was 1.9% of the original peat humic acid. However, the yield of aromatic hydrocarbons containing 3 to 5 rings from peat humic acid was approximately equal to those from the other substances. From the results, it is assumed that peat humic acid has no polycyclic ring systems as the aromatic structure, and that the polycyclic aromatic hydrocarbons produced by zinc-dust distillation were formed by a rearrangement and condensation of oxygen containing structures during the reaction.

  9. Stratigraphic analysis of the Sterkfontein StW 573 Australopithecus skeleton and implications for its age.

    Science.gov (United States)

    Bruxelles, Laurent; Clarke, Ronald J; Maire, Richard; Ortega, Richard; Stratford, Dominic

    2014-05-01

    StW 573, Little Foot, is the most complete Australopithecus skeleton yet discovered, with many of its bones found in their correct anatomical position. Since the discovery of the in situ skeleton in the Silberberg Grotto in 1997, several teams have attempted to date the fossil. This appeared a simple process because several flowstones are inter-bedded in the breccia above and below StW 573. Dating of these flowstones, using U-Pb (uranium-lead) isotope decay techniques, gave younger results than expected from the fauna and stratigraphic position, around 2.2 Ma (millions of years). Our recent stratigraphic, micromorphological and geochemical studies revealed that the stratigraphy is much more complicated than was previously thought, with localized post-depositional processes leading to the creation of voids within the breccia around the skeleton. These voids were then filled by multiple generations of flowstone growth. The research we present here demonstrates that the proposed dates based on the flowstone deposition can give only a minimum age for StW 573 and that the flowstone formation came after, and probably long after, the breccia deposition. If one takes account of the long evolution of these karst fillings, StW 573 appears to be significantly older than 2.2 Ma. PMID:24698198

  10. Quantitative radiological determination of calcium concentrations in the skeleton

    International Nuclear Information System (INIS)

    A simple and practical apparatus and method has been developed in which the Ca concentration in a region 2.5 mm wide in the centre of the middle phalanx of the fourth finger is determined by densitometric evaluation of X-ray pictures. The following results were obtained. Screen films were better suited for densitometric pictures than non-screen films. Two methods of printing were compared. The object of measurement and the object of reference must be similar, with regard to structure and material. An accurate determination of the content of lime salts is possible only with two biological objects of reference. In spite of standardized imaging techniques, there were deviations in radiation absorption higher than 20% with the screen film. This is assumed to be due to inconstant X-ray doses. The range of applications of the method is limited by irregularities of the X-ray screens and by imaging errors due to inconstant X-ray doses. Changes in the calcium content of the finger bones can be detected above a value of +-7%. (orig./MG)

  11. Volatile constituents of Melissa officinalis leaves determined by plant age.

    Science.gov (United States)

    Nurzyńska-Wierdak, Renata; Bogucka-Kocka, Anna; Szymczak, Grazyna

    2014-05-01

    The present study investigated changes in the content and chemical composition of the essential oil extracted by hydrodistillation from air-dried Melissa officinalis L. (lemon balm) leaves in the first and second year of plant growth. The lemon balm oil was analysed by GC-MS and GC-FID. The presence of 106 compounds, representing 100% of the oil constituents, was determined in the oil. The predominant components were geranial (45.2% and 45.1%) and neral (32.8% and 33.8%); their proportions in the examined samples of the oil obtained from one- and two-year-old plants were comparable. However, the age of lemon balm plants affected the concentration of other constituents and the proportions of the following compounds were subject to especially high fluctuations: citronellal (8.7% and 0.4%), geraniol (trace amounts and 0.6%), and geranyl acetate (0.5% and 3.0%), as well as, among others, isogeranial, E-caryophyllene, caryophyllene oxide, germacrene D, and carvacrol. The essential oil of two-year-old plants was characterized by a richer chemical composition than the oil from younger plants. PMID:25026727

  12. Rock fracture skeleton tracing by image processing and quantitative analysis by geometry features

    Science.gov (United States)

    Liang, Yanjie

    2016-06-01

    In rock engineering, fracture measurement is important for many applications. This paper proposes a novel method for rock fracture skeleton tracing and analyzing. As for skeleton localizing, the curvilinear fractures are multiscale enhanced based on a Hessian matrix, after image binarization, and clutters are post-processed by image analysis; subsequently, the fracture skeleton is extracted via ridge detection combined with a distance transform and thinning algorithm, after which gap sewing and burrs removal repair the skeleton. In regard to skeleton analyzing, the roughness and distribution of a fracture network are respectively described by the fractal dimensions D s and D b; the intersection and fragmentation of a fracture network are respectively characterized by the average number of ends and junctions per fracture N average and the average length per fracture L average. Three rock fracture surfaces are analyzed for experiments and the results verify that both the fracture tracing accuracy and the analysis feasibility are satisfactory using the new method.

  13. Iterating skeletons

    DEFF Research Database (Denmark)

    Dieterle, Mischa; Horstmeyer, Thomas; Berthold, Jost;

    2012-01-01

    successively improving data, the repeated instantiation of a skeleton incurs a certain overhead that could be saved by reusing existing processes, threads and communication structures. This is especially important when running parallel applications in a distributed environment. However, customising a...... particular skeleton ad-hoc for repeated execution turns out to be considerably complicated, and raises general questions about introducing state into a stateless parallel computation. In addition, one would strongly prefer an approach which leaves the original skeleton intact, and only uses it as a building...

  14. HEU age determination

    International Nuclear Information System (INIS)

    A technique has been developed to determine the Highly Enriched Uranium (HEU) Age which is defined as the time since the HEU was produced in an enrichment process. The HEU age is determined from the ratios of relevant uranium parents and their daughters viz 230Th/234U and 231Pa/235U. Uranium isotopes are quantitatively measured by their characteristic gammas and their daughters by alpha spectroscopy. In some of the samples where HEU is enriched more than 99%, the only mode of HEU age determination is by the measurement of 231Pa since there is negligible quantity of 230Th due to very low atom concentrations of 234U in the sample. In this paper we have presented data and methodology of finding the age of two HEU samples

  15. Determination of the Topology Skeleton of Magnetic Fields in a Solar Active Region

    Institute of Scientific and Technical Information of China (English)

    Hui Zhao; Jing-Xiu Wang; Jun Zhang; Chi-Jie Xiao; Hai-Min Wang

    2008-01-01

    Magnetic topology has been a key to the understanding of magnetic energy re-lease mechanism. Based on observed vector magnetograms, we have determined the three-dimensional (3D) topology skeleton of the magnetic fields in the active region NOAA 10720.The skeleton consists of six 3D magnetic nulls and a network of corresponding spines, fans,and null-null lines. For the first time, we have identified a spiral magnetic null in Sun's corona.The magnetic lines of force twisted around the spine of the null, forming a 'magnetic wreath'with excess of free magnetic energy and resembling observed brightening structures at extra-ultraviolet (EUV) wavebands. We found clear evidence of topology eruptions which are re-ferred to as catastrophic changes of topology skeleton associated with a coronal mass ejection(CME) and an explosive X-ray flare. These results shed new lights on the structural complex-ity and its role in explosive magnetic activity. The concept of flux rope has been widely used in modelling explosive magnetic activity, although their observational identity is rather ob-scure or, at least, lacking of necessary details up to date. We suggest that the magnetic wreath associated with the 3D spiral null is likely an important class of the physical entity of flux ropes.

  16. Determination of the uptake rates of the bone for 99m-Tc-methylendiphosphonate by means of gamma-camera-scintiscanning and checking its diagnostic value for various skeleton diseases

    International Nuclear Information System (INIS)

    A model of uptake of labelled phosphate in the bones was used to derive a method of calculating the uptake rates for 99m-Tc-MDP. The precondition was the measurement of the change in radioactivity by means of a gamma camera within the lumbal part of the spine over 1 hour. The method was applied on 49 patients (7 with healthy bones, 6 cases of hyperparathyreoidism, 10 of osteoprosis, 9 cases of osteomalacia, 1 case of hypoparathyreoidism, 10 cases of ankylosing spondylitis, 6 tumours affecting the skeleton). Osteomalacia, ankylosing spondylitis, tumours, and, in 50% of the cases, hyperparathyreoidism could be differentiated from normal findings more significantly than using conventional scintiscanning. The author's expectations were met by the method. It is suitable for diagnosing metabolic osteopathis and controlling therapy in circumscribed bone foci. (orig.)

  17. The ossification principle of the laryngeal skeleton

    International Nuclear Information System (INIS)

    In 94 decreased of both sexes aged 15 to 79 who had not has any affections of the larynx itself, the laryngeal skeleton was X-rayed after removing the soft parts, to demonstrate the ossification processes. Furthermore the deformation of the thyroid cartilage caused at the larynx by the laryngopharyngeal muscle in the act of swallowing was experimentally induced and determined with the aid of strain gauges. (orig.)

  18. Radiation exposure by Tc-99m-methyldiphosphonate - development and use of a biophysical model for the determination of the local dose distribution in growth zones of a child's skeleton

    International Nuclear Information System (INIS)

    For the determination of the data necessary for dose calculations of an intraveneous application of Tc-99m-MDP in children, ages 3 months to 7 years, test data for the biokinetics of MDP in the whole body as well as in body areas with and without radioactive concentrations was determined by the use of a whole body activity counter and a gamma camera. These investigations were supplemented by laboratory data on the radioactive decay of Tc-99m-MDP in blood serum and on the urinary excretion of MDP. For the determination of the target volume of epiphyseal growth areas with radioactive concentrations distortion corrected measurements of the patient from the bone scintographs were compared to the biological data taken from our X-ray images. The radiation exposure of these growth areas was calculated with consideration of results from animal investigations as well as under the assumption that larger target volumes could be present in the patients. In the animal investigations the organ distribution of the MDP at various times after application, along with the biokinetic data of MDP in the whole body was ascertained as well as the distribution along long hollow bones. The calcium distribution was activationally analytically ascertained along long hollow bones in a young and an adult dog. It was attempted in the animal investigations to autoradiographically present the microdistribution of MDP in border regions epiphyseal cartilage/epiphyseal center and epiphyseal cartilage/metaphyseal growth plate. (orig./MG)

  19. Age determination and geological studies

    International Nuclear Information System (INIS)

    Two hundred and eight potassium-argon age determinations carried out on Canadian rocks and minerals are reported. Each age determination is accompanied by a description of the rock and mineral concentrate used; brief interpretative comments regarding the geological significance of each age are also provided where possible. The experimental procedures employed are described in brief outline and the constants used in the calculation of ages are listed. Two geological time-scales are reproduced in tabular form for ready reference and an index of all Geological Survey of Canada K-Ar age determinations published in this format has been prepared using NTS quadrangles as the primary reference

  20. Determination of age, longevity and age at reproduction of the frog Microhyla ornata by skeletochronology

    Indian Academy of Sciences (India)

    Suresh M Kumbar; Katti Pancharatna

    2001-06-01

    Skeletochronological estimation of age, longevity, age at sexual maturity and breeding of Microhyla ornata was done. Frogs ( = 62) were collected locally in August (rainy season) 1997 and brought to the laboratory. Body mass and snout-vent-length (SVL) of each frog was recorded; the 4th toe of both the hind limbs was clipped under anaesthesia, fixed in 10% formalin, demineralized in 5% nitric acid and processed for histology. Limb bones (femur, humerus, tibiofibula and radioulna) of 6 large sized frogs were also processed for skeletochronology in order to study the rate of resorption. Gonads of 25 frogs (belonging to different body size ranges) were processed for histology in order to ascertain the gametogenic status of individual frogs. One to four growth rings consisting of growth zones and lines of arrested growth (LAGs) were noticed in frogs of different body sizes; the number of LAGs remained identical in all the limb bones and phalanges in 5 out of 6 frogs. Back calculation indicated that the resorption rate is very low in this frog. Male frogs possessed sperm bundles in seminiferous tubules in the 1st year, while females showed yolky follicles in the ovary in the 2nd year. Frogs found in amplexus were 3–5 years old. The results suggest that this frog may live for a maximum of 5 years in the natural population.

  1. Age determination of ground-waters by means of carbon 14

    International Nuclear Information System (INIS)

    At present the age determination of ground-waters aged between 1,500 and approximately 40,000 years is only possible by measuring their 14C content. A precise age assignment can be established in slightly mineralised waters, whereas it becomes vague in mineralised waters, particularly in acidulous springs. In general, additional information and data are required about the 13C, D, 18O, 3H, 85Kr and the 39Ar contents, about the ph value, temperature and the principal ions. (DG)

  2. Genetic analysis of 7 medieval skeletons from the Aragonese Pyrenees

    OpenAIRE

    Núńez, Carolina; Sosa, Cecilia; Baeta, Miriam; Geppert, Maria; Turnbough, Meredith; Phillips, Nicole; Casalod, Yolanda; Bolea, Miguel; Roby, Rhonda; Budowle, Bruce; Martínez-Jarreta, Begońa

    2011-01-01

    Aim To perform a genetic characterization of 7 skeletons from medieval age found in a burial site in the Aragonese Pyrenees. Methods Allele frequencies of autosomal short tandem repeats (STR) loci were determined by 3 different STR systems. Mitochondrial DNA (mtDNA) and Y-chromosome haplogroups were determined by sequencing of the hypervariable segment 1 of mtDNA and typing of phylogenetic Y chromosome single nucleotide polymorphisms (YSNP) markers, respectively. Po...

  3. Genetic analysis of 7 medieval skeletons from Aragonese Pyrenees

    OpenAIRE

    Núńez, Carolina; Sosa, Cecilia; Baeta, Miriam; Geppert, Maria; Turnbough, Meredith; Phillips, Nicole; Casalod, Yolanda; Bolea, Miguel; Roby, Rhonda; Budowle, Bruce; Martínez-Jarreta, Begońa

    2011-01-01

    Aim To perform a genetic characterization of 7 skeletons from medieval age found in a burial site in the Aragonese Pyrenees. Methods Allele frequencies of autosomal short tandem repeats (STR) loci were determined by 3 different STR systems. Mitochondrial DNA (mtDNA) and Y-chromosome haplogroups were determined by sequencing of the hypervariable segment 1 of mtDNA and typing of phylogenetic Y chromosome single nucleotide polymorphisms (Y-SNP) markers, respectively. Possible familial relationsh...

  4. Electrostatic skeletons

    OpenAIRE

    Eremenko, Alexandre; Lundberg, Erik; Ramachandran, Koushik

    2013-01-01

    Let u be the equilibrium potential of a compact set K. An electrostatic skeleton of K is a positive measure whose closed support has connected complement and no interior, and whose potential is equal to u near infinity. We prove the existence of an electrostatic skeleton for any simplex.

  5. Age Determination of Trace Plutonium by Using ID-MC-ICP-MS

    Institute of Scientific and Technical Information of China (English)

    2008-01-01

    <正>In the analysis of the origin of plutonium, the isotopic composition and the age of the material are very important. The age is the first parameter necessary to be determined when deducing the history of the

  6. Foramen Tympanicum or Foramen of Huschke: A Bioarchaeological Study on Human Skeletons from an Iron Age Cemetery at Tabriz Kabud Mosque Zone

    Directory of Open Access Journals (Sweden)

    Jafar Rezaian

    2015-07-01

    Full Text Available The foramen tympanicum is an anatomical variation that is created in the tympanic plate of temporal bone during the first year of life. The tympanic plate grows and foramen tympanicum is gradually closed by about the fifth postnatal year. However, due to a defect in normal ossification, foramen tympanicum sporadically remains throughout life. The construction of a shopping center in Tabriz, northwest of Iran, led to the discovery of an Iron Age cemetery (1500-500 BC. Several tombs have been uncovered below one meter of sterile soil so far and a thick level of architectural debris from the medieval city has been discovered. Up to now, no bioarchaeological data has been gathered about the burials in this area. Thus, the present study aimed to evaluate the prevalence of foramen tympanicum in this area. In this study, 45 skeletons were studied and the prevalence of this foramen was about 4.4% bilaterally. We also reported on two babies with fused and un-fused squamotympanic fissure. The persistence of this foramen is a possible risk factor for otologic complications after arthroscopy of the temporomandibular joint and salivary gland fistula through this foramen. The closure of this foramen could be also used for age estimation in sub-adult individuals. The incidence of this trait in this study was similar to other available studies on modern skeletons.

  7. Determining the relative age of blue ballpoint ink by gas chromatography

    Institute of Scientific and Technical Information of China (English)

    Yao Lijuan; Zhao Pengcheng; Wang Jinghan; Wang Yanji

    2006-01-01

    A method for identifying the writing age of blue ballpoint pen ink has been established due to the imperative demand in forensic laboratories.The content of the volatile components in blue ballpoint pen ink were determined by gas chromatography(GC).The absorbance of dye in blue ballpoint pen ink was measured by UV-Vis spectrometry A writing age curve of the ink was established using the ratio of the content of the volatile components to the dye,based on the identification of 74 kinds of blue ballpoint pen ink of domestic and international origins.The change of benzene alcohol or phenoxetol with the writing age was also tested.Different kinds of blue ballpoint pen ink were detected and the repeatability of the experiment was investigated.The results indicate that the method is reliable,sensitive,systematic and is especially suitable for practical use.

  8. Age determination by back length for African savanna elephants: extending age assessment techniques for aerial-based surveys.

    Directory of Open Access Journals (Sweden)

    Morgan J Trimble

    Full Text Available Determining the age of individuals in a population can lead to a better understanding of population dynamics through age structure analysis and estimation of age-specific fecundity and survival rates. Shoulder height has been used to accurately assign age to free-ranging African savanna elephants. However, back length may provide an analog measurable in aerial-based surveys. We assessed the relationship between back length and age for known-age elephants in Amboseli National Park, Kenya, and Addo Elephant National Park, South Africa. We also compared age- and sex-specific back lengths between these populations and compared adult female back lengths across 11 widely dispersed populations in five African countries. Sex-specific Von Bertalanffy growth curves provided a good fit to the back length data of known-age individuals. Based on back length, accurate ages could be assigned relatively precisely for females up to 23 years of age and males up to 17. The female back length curve allowed more precise age assignment to older females than the curve for shoulder height does, probably because of divergence between the respective growth curves. However, this did not appear to be the case for males, but the sample of known-age males was limited to ≤27 years. Age- and sex-specific back lengths were similar in Amboseli National Park and Addo Elephant National Park. Furthermore, while adult female back lengths in the three Zambian populations were generally shorter than in other populations, back lengths in the remaining eight populations did not differ significantly, in support of claims that growth patterns of African savanna elephants are similar over wide geographic regions. Thus, the growth curves presented here should allow researchers to use aerial-based surveys to assign ages to elephants with greater precision than previously possible and, therefore, to estimate population variables.

  9. Asteroid age distributions determined by space weathering and collisional evolution models

    CERN Document Server

    Willman, Mark; 10.1016/j.icarus.2010.02.017

    2010-01-01

    We provide evidence of consistency between the dynamical evolution of main belt asteroids and their color evolution due to space weathering. The dynamical age of an asteroid's surface \\citep{bib.bot05a,bib.nes05} is the time since its last catastrophic disruption event which is a function of the object's diameter. The age of an S-complex asteroid's surface may also be determined from its color using a space weathering model \\citep[e.g.][]{bib.wil10,bib.jed04,bib.wil08,bib.mar06}. We used a sample of 95 S-complex asteroids from SMASS and obtained their absolute magnitudes and $u,g,r,i,z$ filter magnitudes from SDSS. The absolute magnitudes yield a size-derived age distribution. The $u,g,r,i,z$ filter magnitudes lead to the principal component color which yields a color-derived age distribution by inverting our color-age relationship, an enhanced version of the `dual $\\tau$' space weathering model of \\citet{bib.wil10}. We fit the size-age distribution to the enhanced dual $\\tau$ model and found characteristic w...

  10. Female Reproductive Decline Is Determined by Remaining Ovarian Reserve and Age

    OpenAIRE

    Wilkosz, Pawel; Gareth D. Greggains; Tanbo, Tom G.; Fedorcsak, Peter

    2014-01-01

    The early decline and loss of female fertility in humans and other species represents an evolutionary paradox. Despite being born with a vast stock of oocytes, females encounter an exhaustion of ovarian reserve and sterility half way through their natural lives. Female reproductive ageing has been proposed to proceed as an ongoing decline in ovarian reserve, determined by remaining ovarian follicle number. However, despite extensive modelling, the respective contributions of intra-, inter-, a...

  11. Comparison of observed skeleton retention of strontium in average indian adult with the value predicted by the ICRP biokinetic model

    International Nuclear Information System (INIS)

    The daily dietary intake of strontium and its content in skeleton, for an Indian adult population group were estimated by experimentally measuring its concentration in total cooked diet and autopsy skeleton samples using radiochemical neutron activation analysis. The data on daily dietary intake of strontium were used to compute its contents in skeleton using ICRP Publication 67 biokinetic model for strontium. The theoretically computed value of strontium (213.8 mg) compared favourably with the measured values (GM 181.2 mg) in an urban population group living in Mumbai representing an average Indian adult (Reference Indian Man). (authors)

  12. Daily physical activity as determined by age, body mass and energy balance

    OpenAIRE

    Klaas R Westerterp

    2015-01-01

    Aim Insight into the determinants of physical activity, including age, body mass and energy balance, facilitates the design of intervention studies with body mass and energy balance as determinants of health and optimal performance. Methods An analysis of physical activity energy expenditure in relation to age and body mass and in relation to energy balance, where activity energy expenditure is derived from daily energy expenditure as measured with doubly labelled water and body movement is m...

  13. Age of an Indonesian Fossil Tooth Determined by Electron Paramagnetic Resonance

    Energy Technology Data Exchange (ETDEWEB)

    Bogard, JS

    2004-04-07

    The first fossil hominid tooth recovered during 1999 excavations from the Cisanca River region in West Java, Indonesia, was associated with a series of bovid teeth from a single individual that was recovered 190 cm beneath the hominid tooth. The age of the fossil bovid teeth was determined using electron paramagnetic resonance (EPR) analysis as part of an effort to bracket the age of the hominid tooth. The EPR-derived age of the bovid teeth is (5.16 {+-} 2.01) x 10{sup 5} years. However, the age estimate reported here is likely an underestimate of the actual age of deposition since evidence of heating was detected in the EPR spectra of the bovid teeth, and the heating may have caused a decrease in the intensity of EPR components on which the age calculation is based.

  14. Age-independent osteopathology in skeletons of a South American cervid, the Patagonian huemul (Hippocamelus bisulcus).

    Science.gov (United States)

    Flueck, Werner T; Smith-Flueck, Jo Anne M

    2008-07-01

    The huemul (Hippocamelus bisulcus), an endemic Patagonian deer, has been endangered for decades. Although conservation in Argentina has been directed at the 350-600 remaining huemul, the population has not recovered. In initial studies on the potential effects of diseases on huemul population dynamics, skeletal remains collected between 1993 and 2007 in the Andes (41-45 degrees S, 71.5-72 degrees W) were examined macroscopically for osteopathologic changes. Bones from six huemul were free of lesions, findings were inconclusive in 13 huemul with less than three bones, and osteopathologic processes were detected in 13 adults. Considering the limited remains/case, the prevalence of osteopathy (52%) among adults probably is conservative; 63% showed mandibular, 100% maxillary, and 78% appendicular lesions. Although predation represented the actual cause of death, the observed skeletal lesions would affect predator avoidance, possibly explaining the low average adult age (3.1 yr) and lack of population recovery. Compared with other studies in ungulates, huemul were affected at a younger age, and they had more severe pathologic changes. Due to the chronic nature of disease, low huemul population density, physiognomy, and spatiotemporal pattern of lesions, we discard senescence; gender; fulminating infections; congenital anomalies; metabolic, endocrine, genetic, or neurologic disorders; parasitism or marasmus; and fluorosis as primary etiologic factors. We hypothesize that generalized secondary chronic alveolar osteomyelitis and osteoarthritis in huemul is related to the nutritional ecology of these animals. Selenium deficiency, which impairs bone metabolism and causes periodontitis in ruminants, occurs in the region and it is more prevalent at high altitudes. Traditional winter grounds at low elevations, sometimes far from high mountains, have been converted to livestock production, which has eliminated migratory behavior and keeps huemul in remote high-elevation refuges

  15. Determination of the Rubidium Decay Constant by Age Comparison Against the U-Pb System

    Science.gov (United States)

    Nebel, O.; Mezger, K.; Scherer, E. E.; Davies, G. R.

    2006-12-01

    The currently accepted Rb decay constant (λ 87Rb) was suggested by the Subcommission on Geochronology [1] is 1.42 x 10-11yr-1, and has a potential precision at the percent level at best [2]. This value has been used in most Rb-Sr studies in the last three decades. Several attempts to refine λ87Rb by different techniques yielded results that, despite excellent reported precisions, differed from the proposed value and also from each other. In a recent evaluation of published calibrations of the decay constant, Begemann et al. [2] suggested a lower value [~ 1.40 x 10-11yr-1] but also called for a re-determination of λ87Rb to check its accuracy and significantly improve the precision. Subsequent re-determinations [3,4] yielded values that differ significantly from each other and from that proposed by the Subcommission on Geochronology [1], one of which being higher [3], the other one lower [4] than the recommended value. Therefore, at present, there is no consensus on the λ87Rb to be used in Rb-Sr chronology. Here we report three individual determinations of λ87Rb by the method of age comparison. This entails solving for λ87Rb using 1) the measured slopes of high precision Rb-Sr isochrons from igneous rocks and minerals and 2) the emplacement ages of these samples as determined by the precise and presumably accurate U-Pb method. The precision of the measured 87Rb/86Sr has been improved to ~0.2% by measuring Rb concentrations by isotope dilution MC-ICPMS [5] (cf. ~1% for TIMS data). A challenging aspect of Rb-Sr studies is that of spike calibration, which is generally performed using standards prepared from salts of Rb and Sr rather than pure metals. The Rb/Sr values of individual spikes calibrated against two standard solutions made from different salts (iodide and carbonate) agree to within 0.15%, strongly suggesting that the stoichiometry of the salts, after careful dehydration, is sufficiently ideal for accurate spike calibrations. The calibration was checked

  16. Skeletonization Algorithm for Numeral Patterns

    Directory of Open Access Journals (Sweden)

    Gupta Rakesh

    2008-12-01

    Full Text Available Skeletonization has been a part of morphological image processing for a wide variety of applications. Skeletonization algorithms have played an important role in the preprocessing phase of OCR systems. Many algorithms for vectorization by skeletonization have been devised and applied to a great variety of pictures and drawings for data compression, pattern recognition and raster-to-vector conversion. The vectorization algorithms often used in pattern recognition tasks also require one-pixel-wide lines as input. But parallel skeletonization algorithms which generate one-pixel-wide skeletons can have difficulty in preserving the connectivity of an image or generate spurious branches. In this paper an alternative parallel skeletonization algorithm has been developed and implemented. This algorithm is better than already existing algorithms in terms of connectivity and spurious branches. A few most common skeletonization algorithms have been implemented and evaluated on the basis of performance parameters and compared with newly developed algorithm.

  17. Age validation of great hammerhead shark (Sphyrna mokarran), determined by bomb radiocarbon analysis

    OpenAIRE

    Passerotti, Michelle S.; John K. Carlson; Piercy, Andrew N.; Campana, Steven E.

    2010-01-01

    Preliminary validation of annual growth band deposition in vertebrae of great hammerhead shark (Sphyrna mokarran) was conducted by using bomb radiocarbon analysis. Adult specimens (n=2) were collected and thin sections of vertebral centra were removed for visual aging and use in radiocarbon assays. Vertebral band counts were used to estimate age, and year of formation was assigned to each growth band by subtracting estimated age from the year of capture. A total of 10 samples were extra...

  18. Determination of the bone-mineral content of the peripheral skeleton (ulna and calcaneus) in chronic renal failure patients on maintenance dialysis using 125 I-photon absorptiometry

    International Nuclear Information System (INIS)

    The bone-mineral content (BMC) of the peripheral skeleton was measured in 53 chronic renal-failure patients on maintenance dialysis using the 125 I photon absorptiometry according to Cameron. 39.6% of the patients were found to have a clearly pathological calcium content in calcaneus and ulna (33%). In total BMC assessments 43.4% of the patients examined showed strongly reduced BMC values at two measurement sites at least. Average bone-mineral content was below the value of the corresponding normal groups in all age groups of the dialysis patients. In addition, a significant correlation was verified to exist between the calcium contents of calcaneus and ulna. A significant correlation was found as well between reduced BMC values and dialysis duration. The correlation between the increased serum level of alkaline phosphatase and the reduced mineral content of the skeleton was significant as well. A minor but not significant correlation existed between the increase of the parathormone (PTH) level in the serum and the decrease of calcium content in calcaneus and ulna. A good correlation was found when contrasting the results of visual roentgenography and the BMC values established by photodensitometry: the median BMC value of patients with clear pathological X-ray findings was significantly below the one of patients without pathological X-ray findings. However, photon absorptiometry is superior to the subjective evaluation of X-ray pictures in the early diagnosis of bone diseases involving bone-mineral loss. (orig.)

  19. Automated characterization of cell shape changes during amoeboid motility by skeletonization

    Directory of Open Access Journals (Sweden)

    Robinson Douglas N

    2010-03-01

    Full Text Available Abstract Background The ability of a cell to change shape is crucial for the proper function of many cellular processes, including cell migration. One type of cell migration, referred to as amoeboid motility, involves alternating cycles of morphological expansion and retraction. Traditionally, this process has been characterized by a number of parameters providing global information about shape changes, which are insufficient to distinguish phenotypes based on local pseudopodial activities that typify amoeboid motility. Results We developed a method that automatically detects and characterizes pseudopodial behavior of cells. The method uses skeletonization, a technique from morphological image processing to reduce a shape into a series of connected lines. It involves a series of automatic algorithms including image segmentation, boundary smoothing, skeletonization and branch pruning, and takes into account the cell shape changes between successive frames to detect protrusion and retraction activities. In addition, the activities are clustered into different groups, each representing the protruding and retracting history of an individual pseudopod. Conclusions We illustrate the algorithms on movies of chemotaxing Dictyostelium cells and show that our method makes it possible to capture the spatial and temporal dynamics as well as the stochastic features of the pseudopodial behavior. Thus, the method provides a powerful tool for investigating amoeboid motility.

  20. Image segmentation and registration algorithm to collect thoracic skeleton semilandmarks for characterization of age and sex-based thoracic morphology variation.

    Science.gov (United States)

    Weaver, Ashley A; Nguyen, Callistus M; Schoell, Samantha L; Maldjian, Joseph A; Stitzel, Joel D

    2015-12-01

    Thoracic anthropometry variations with age and sex have been reported and likely relate to thoracic injury risk and outcome. The objective of this study was to collect a large volume of homologous semilandmark data from the thoracic skeleton for the purpose of quantifying thoracic morphology variations for males and females of ages 0-100 years. A semi-automated image segmentation and registration algorithm was applied to collect homologous thoracic skeleton semilandmarks from 343 normal computed tomography (CT) scans. Rigid, affine, and symmetric diffeomorphic transformations were used to register semilandmarks from an atlas to homologous locations in the subject-specific coordinate system. Homologous semilandmarks were successfully collected from 92% (7077) of the ribs and 100% (187) of the sternums included in the study. Between 2700 and 11,000 semilandmarks were collected from each rib and sternum and over 55 million total semilandmarks were collected from all subjects. The extensive landmark data collected more fully characterizes thoracic skeleton morphology across ages and sexes. Characterization of thoracic morphology with age and sex may help explain variations in thoracic injury risk and has important implications for vulnerable populations such as pediatrics and the elderly. PMID:26496701

  1. Asteroid age distributions determined by space weathering and collisional evolution models

    OpenAIRE

    Willman, Mark; Jedicke, Robert

    2010-01-01

    We provide evidence of consistency between the dynamical evolution of main belt asteroids and their color evolution due to space weathering. The dynamical age of an asteroid's surface \\citep{bib.bot05a,bib.nes05} is the time since its last catastrophic disruption event which is a function of the object's diameter. The age of an S-complex asteroid's surface may also be determined from its color using a space weathering model \\citep[e.g.][]{bib.wil10,bib.jed04,bib.wil08,bib.mar06}. We used a sa...

  2. Extraction of bone structure with a single-scan skeletonization driven by distance

    OpenAIRE

    Arlicot, Aurore; NORMAND, Nicolas; Amouriq, Yves; Guédon, Jeanpierre

    2011-01-01

    Shape description is an important step in image analysis. Skeletonization methods are widely used in image analysis since they are a powerful tool to describe a shape. This paper presents a new single-scan skeletonization using different diskrete distances. The application of this method is the extraction of caracteristics from µCT images in order to estimate the bone state.

  3. Independent SST and SSS reconstructions from coral skeleton, by using Neural Network

    Science.gov (United States)

    Juillet-Leclerc, A.

    2009-12-01

    The Pacific Warm Pool is strongly affected by interannual climatic variability. However, few instrumental measurements document environmental changes prior to 1955, in particular in the southern hemisphere. Studies have thus to be based on few instrumental data complemented by interpolations and /or indirect tracers, such as coral skeleton. This is regarded as the best archive of tropical oceans and may provide continuous records of seasurface temperature and salinity (SST and SSS) during the past at, high resolution. However, the different approaches up to now developed do not allow independent reconstructions of SST and SSS. In addition, chemical biases caused by biological activity prevent relevant conversion of measured values into environmental factors. Our understanding of the coral skeletogenesis is sufficient to suppose that the mechanism of mineral deposition is complex, strongly impacted by biology, governed by other physical processes than that earlier considered, but not enough to establish quantified relationships taking into account all the factors involved. In this case, the use of Neural Network, well suited to non-linear processes may not be totally assimilated with a black box. This statistical treatment has been applied on a coral core collected in Yasawa (Fiji Archipelago), by considering SST and SSS measured from 1960 and 1997 as learning phase. Reconstructions performed from 1910 to 1960 indicate that only four strong ENSO occurred prior to 1960. Both SST and SSS have been impacted confirming that SPCZ migration is associated with oceanic advection.

  4. Skeleton castings dynamic load resistance

    Directory of Open Access Journals (Sweden)

    M. Cholewa

    2013-06-01

    Full Text Available Purpose: The article is to show selected results of research in a field of new type of cast spatial composite reinforcements. This article shows skeleton casting case as a particular approach to continuous, spatial composite reinforcement.Design/methodology/approach: The research is concerning properties of cast spatial microlattice structures called skeleton castings. In this paper results of impact test of skeleton casting with octahedron elementary cell were shown. The selection of internal topology of skeleton casting was based on numerical simulations of stress distribution.Findings: The possibility of manufacturing of geometrically complex skeleton castings without use of advanced techniques was confirmed.Research limitations/implications: With use of computer tomography, analysis of deformation mechanisms was carried out. Different levels of impact energies were usedPractical implications: Spatial skeleton casting with octahedron elementary cell confirmed their usefulness as impact energy absorbers.Originality/value: The overall aim of presented research was to determine the mechanisms of skeleton castings deformation processes. Thanks to CT data next step will be to create accurate numerical model for further simulation and design optimization.

  5. Age Determination of Microlepidotus brevipinnis (Steindachner, 1869 (Pisces: Haemulidae in the Coast of Jalisco, Mexico, by Reading Otoliths and Scales

    Directory of Open Access Journals (Sweden)

    E.G. Cabral-Solis

    2010-01-01

    Full Text Available This study deals with age determination of the brassy grunt Microlepidotus brevipinnis by reading otoliths (sagittae and scales which allowed the identification of 13 age groups. Growth of otoliths and scales is proportional to the growth of the fish. The time of formation of fast and slow growth bands in sagittae, as well as the time of ring formation in the scales is one year. The highest growth in length of this species takes place during the first year of life, in which the organism reaches 125.0 mm, this reduces natural mortality of the individuals by decreasing depredation. Growth in weight of this species is isometric. Sexual differentiation of the organisms is apparent after the age of two years and there were differences in the average length for each age in scales and otoliths for males and females. The age of other members of the Haemulidae family were compared with those obtained in the present study and M. brevipinnis reaches its oldest age in 13 years. It occupies a middle point (442.4 mm in relation to the total lengths of other haemulids in the Mexican Pacific coast.

  6. NMR spectroscopy of lactate in the skeleton muscle: visibility, quantification and measurement of carbon 13 enrichment by double quantum edition

    International Nuclear Information System (INIS)

    The metabolism of skeleton muscles gave rise to numerous research works since the beginning of the century in order to make some reply about the muscle physiology with the will to improve the sport performances or the understanding of muscles diseases. This metabolism is complex and the lactate has an importance place; the purpose of this work is to answer these questions with some strategy studies by nuclear magnetic resonance spectroscopy. (N.C.)

  7. Biology of bone and how it orchestrates the form and function of the skeleton

    OpenAIRE

    Sommerfeldt, D; Rubin, C.

    2001-01-01

    The principal role of the skeleton is to provide structural support for the body. While the skeleton also serves as the body's mineral reservoir, the mineralized structure is the very basis of posture, opposes muscular contraction resulting in motion, withstands functional load bearing, and protects internal organs. Although the mass and morphology of the skeleton is defined, to some extent, by genetic determinants, it is the tissue's ability to remodel – the local resorption and formation of...

  8. Variation of radon retention parameters for radium-burdened dog skeletons as a function of exposure age and dosage level

    International Nuclear Information System (INIS)

    Radium-226 was administered to 36 beagles at various levels in eight semimonthly injections at ages 60 to 160, 120 to 220, or 435 to 535 days. Approximately 400 individual radon retention values were obtained from γ-ray spectra taken at intervals over the life span of the animals. Radon retention was fitted by regression analysis to a power function of the form At/sup b/ (t = time after injection midpoint). Mean values and associated standard errors of the parameters anti A (SE) and anti b (SE), for animals of both sexes given 10 μCi/kg body weight at injection midpoint ages of 110, 170, and 485 days were [3.11 (0.15 SE); 0.293 (0.006 SE)], [5.31 (0.38 SE); 0.214 (0.006 SE)], and [6.08 (0.21 SE); 0.200 (0.007 SE)], respectively. The smaller coefficients, A (t = 1-day intercept), and larger exponents, b (rate parameter), found for earlier ages at injection are attributed to age-dependent differences in the mineral density of bone and the intrabone radium distribution pattern. The mean values of the parameters for animals receiving total dosages 226Ra dosage levels are interpreted in terms of radiation damage to bone which alters the degree of mineralization in regions of radium deposition

  9. The determination of age of the fault activities of Shougou Hill, Guangzhou by thermoluminescence dating and nuclear fission track dating

    International Nuclear Information System (INIS)

    The age of the fault activities had been determined by TL dating and nuclear fission track dating. The results show that the fault of Shougou Hill had large and intense activities in mid-cenozoic era, however, intense activities still occurred in early pleistocene and mid-pleistocene. The last activity of the fault occurred 430 000 years ago. The data of TL dating are conformable with data of nuclear fission track dating

  10. Root dentine transparency: age determination of human teeth using computerized densitometric analysis.

    Science.gov (United States)

    Drusini, A; Calliari, I; Volpe, A

    1991-05-01

    Root dentine transparency (RDT) was used to estimate the ages of human subjects from 152 intact teeth. Teeth were from 134 subjects, both historical and recent, of known age and sex. The aims of this work are 1) to compare two methods of using RDT to estimate age; 2) to test the applicability of the regression formulae for estimating age obtained from a recent sample on an historical sample; and 3) to estimate the suitability of RDT to determine age at death of 100-year-old skeletons. RDT was measured by two techniques: 1) computerized densitometric analysis and 2) vernier caliper. Age estimations based on computerized densitometric analysis were no more accurate than were those determined by caliper measurement; both give a predictive success of +/- 5 years in about 45-48% of cases for premolars. The television-based digitization system has some disadvantages: It is expensive, not portable, and requires some training to use. However, it furnishes a more standardized method, a rapid graphic illustration of the results, and an immediate storage of statistical information for future use. PMID:1853940

  11. Anti-Bacterial effect of Aqueous Garlic Extract (AGE) determined by Disc Diffusion Method against Escherichia coli.

    Science.gov (United States)

    Saha, S; Saha, S K; Hossain, M A; Paul, S K; Gomes, R R; Imtiaz, M; Islam, M M; Nahar, H; Begum, S A; Mirza, T T

    2016-01-01

    The study was performed to determine the antibacterial effect of aqueous extract of garlic (Allium sativum) against standard strain of Escherichia coli ATCC 25922. An interventional study was conducted in Department of Pharmacology and Therapeutics in collaboration with Department of Microbiology, Mymensingh Medical College, Mymensingh. Antibacterial effect of AGE was determined by disc diffusion method. Sensitivity of AGE determined in disc diffusion and the zone of inhibition (ZOI) was 4 mm, 10 mm and 20 mm at 25 μg/10 μl, 50 μg/10 μl and 100 μg/10 μl concentrations respectively. From the findings it is clearly determined the extract has definite antibacterial effect upon Escherichia coli. Further studies are required to detect and isolate the active ingredients present in the Garlic extract as well as detail steps of mechanism responsible for antibacterial effect. Then their effects against the studied organism should be studied in vivo separately and its toxicity profile should also be taken into account. PMID:26931244

  12. Age- and gender-specific differences in left ventricular cardiac function and volumes determined by gated SPET

    International Nuclear Information System (INIS)

    The aim of this study was to determine normative volumetric data and ejection fraction values derived from gated myocardial single-photon emission tomography (SPET) using the commercially available software algorithm QGS (quantitative gated SPET). From a prospective database of 876 consecutive patients who were referred for a 2-day stress-rest technetium-99m tetrofosmin (925 MBq) gated SPET study, 102 patients (43 men, 59 women) with a low (<10%) pre-test likelihood of coronary disease were included (mean age 57.6 years). For stress imaging, a bicycle protocol was used in 79 of the patients and a dipyridamole protocol in 23. Left ventricular ejection fraction (LVEF) and end-diastolic and -systolic volumes (EDV and ESV) were calculated by QGS. EDV and ESV were corrected for body surface area, indicated by EDVi and ESVi. To allow comparison with previous reports using other imaging modalities, men and women were divided into three age groups (<45 years, ≥45 years but <65 years and ≥65 years). Men showed significantly higher EDVi and ESVi values throughout and lower LVEF values when compared with women in the subgroup ≥65 years (P<0.05, ANOVA). Significant negative and positive correlations were found between age and EDVi and ESVi values for both women and men and between LVEF and age in women (Pearson P≤0.01). LVEF values at bicycle stress were significantly higher than at rest (P=0.000, paired t test), which was the result of a significant decrease in ESV (P=0.003), a phenomenon which did not occur following dipyridamole stress (P=0.409). The data presented suggest that LVEF and EDVi and ESVi as assessed by QGS are strongly gender-specific. Although the physiological significance of these results is uncertain and needs further study, these findings demonstrate that the evaluation of cardiac function and volumes of patients by means of QGS should consider age- and gender-matched normative values. (orig.)

  13. Asteroseismic age determination for dwarfs and giants

    CERN Document Server

    Aguirre, V Silva

    2015-01-01

    Asteroseismology can make a substantial contribution to our understanding of the formation history and evolution of our Galaxy by providing precisely determined stellar properties for thousands of stars in different regions of the Milky Way. We present here the different sets of observables used in determining asteroseismic stellar properties, the typical level of precision obtained, the current status of results for ages of dwarfs and giants and the improvements than can be expected in the near future in the context of Galactic archaeology.

  14. Asteroseismic age determination for dwarfs and giants

    DEFF Research Database (Denmark)

    Silva Aguirre, V.; Serenelli, A. M.

    2015-01-01

    Asteroseismology can make a substantial contribution to our understanding of the formation history and evolution of our Galaxy by providing precisely determined stellar properties for thousands of stars in different regions of the Milky Way. We present here the different sets of observables used ...... determining asteroseismic stellar properties, the typical level of precision obtained, the current status of results for ages of dwarfs and giants and the improvements than can be expected in the near future in the context of Galactic archaeology....

  15. Role of the membrane skeleton in preventing the shedding of procoagulant-rich microvesicles from the platelet plasma membrane

    OpenAIRE

    1990-01-01

    The platelet plasma membrane is lined by a membrane skeleton that appears to contain short actin filaments cross-linked by actin-binding protein. Actin-binding protein is in turn associated with specific plasma membrane glycoproteins. The aim of this study was to determine whether the membrane skeleton regulates properties of the plasma membrane. Platelets were incubated with agents that disrupted the association of the membrane skeleton with membrane glycoproteins. The consequences of this c...

  16. Skeleton human bone analysis by ICP-OES and laser ablation-ICP-OES

    International Nuclear Information System (INIS)

    Complete text of publication follows. Samples of skeleton human bone were analyzed using ICP-OES after microwave digestion and LA-ICP-OES. The samples were obtained from a Mexican region where in the XXth century the content of As in the drink water was in high level. The bones were buried perhaps of 60 years. In order to discard the contamination from the local soil where the bones were extracted, several soil samples were analyzed. The presence of As in hair of the same skeletons was previously evaluated, but there is not information with regard to the content of this element in human bone. This is a preliminary study for to evaluate the possibility of use LA-ICP-OES comparative to ICP-OES after acid microwave digestion. The LA-ICP-OES do not require sample preparation, in this case is the main advantage more enough when we have only a few milligrams of sample and bones of very small size. In this condition is too difficult handle the sample and the possibility of contamination is the problem. The direct bone analysis was make using a Infrared NdYAG nanosecond Laser (Brio, France) coupled to a ICP-OES (Perkin Elmer Optima 4300DV). The same ICP-OES was used for the analysis of the digested samples. The typical values obtained for the major elements analyzed were; Ca 25-28%, P 12-15%, Mg 0.15-0.18% and for the minor and trace elements in the order of; Zn 150-200 mg/kg, Cu 5-10 mg/kg, Mn 5-25 mg/kg, Fe 100-500 mg/kg. The elements considered like contaminants were Pb 25-45 mg/kg and As 60-200 mg/kg in some samples. The major elements correlated good between ICP-OES and LA-ICP-OES, however the minor and trace elements not, may be due to poor sensitivity of the ICP-OES. In the future we will be use LA-ICP-MS for the study of the minor and trace elements.

  17. Hamilton-Jacobi skeleton on cortical surfaces.

    Science.gov (United States)

    Shi, Y; Thompson, P M; Dinov, I; Toga, A W

    2008-05-01

    In this paper, we propose a new method to construct graphical representations of cortical folding patterns by computing skeletons on triangulated cortical surfaces. In our approach, a cortical surface is first partitioned into sulcal and gyral regions via the solution of a variational problem using graph cuts, which can guarantee global optimality. After that, we extend the method of Hamilton-Jacobi skeleton [1] to subsets of triangulated surfaces, together with a geometrically intuitive pruning process that can trade off between skeleton complexity and the completeness of representing folding patterns. Compared with previous work that uses skeletons of 3-D volumes to represent sulcal patterns, the skeletons on cortical surfaces can be easily decomposed into branches and provide a simpler way to construct graphical representations of cortical morphometry. In our experiments, we demonstrate our method on two different cortical surface models, its ability of capturing major sulcal patterns and its application to compute skeletons of gyral regions. PMID:18450539

  18. Anthropogenic stressors and eutrophication processes as recorded by stable isotopes compositions in coral skeletons

    Science.gov (United States)

    Levy, O.; Rosenfeld, M.; Loya, Y.; Yam, R.; Mizrachi, I.; Shemesh, A.

    2010-10-01

    The northern Gulf of Aqaba, in the northeastern branch of the Red Sea, is a clear example of humans effecting on the health of fringing reefs. Our results demonstrate the effect of an anthropogenic stressor on the carbon and oxygen stable isotopes compositions, namely net pen fish farming with annual fish production of 2.4×106 kg yr-1. We sampled and studied long coral cores from stressed, remote and intermediate localities and short- term transplanted Porites sp. colonies from the west side of the Gulf of Aqaba to a remote and a polluted sites, respectively. The data shows that mariculture and other human related stressors did not influence the oxygen isotopic signature over a period of two decades. However, the carbon fractionation changed along a geographical gradient and depended on proximity to the source of contamination. We suggest that δ13C of coral skeleton is a promising proxy for identifying long term processes of coral growth under high nutrient loads and potential disturbances to the coral reef ecology.

  19. 人类骨骼衰老及其相关疾病%Human skeleton aging and its related diseases(

    Institute of Scientific and Technical Information of China (English)

    李星慧; 秦娇琴; 贾春媛; 何本进; 韩晶; 杨泽; 张毓洪; 杜建财; 郭忠琴; 张翻弟; 孙亮; 朱小泉; 原惠萍; 杨帆

    2015-01-01

    Age-related fragility fractures are a major public health problem affecting today's society.Obtain and age-related bone loss of bone mass in the growing season are affecting their brittleness risks .High-resolution peripheral quantitative ( HRpQCT) in-crease the development of micro-structures on the spongy bone and cortical bone in the body throughout life changing .Studies have shown that teenagers use HRpQCT can see growing in the distal forearm fracture and transient increase in cortical bone changes relat -ed, including cortical thinning and increased cortical porosity .Children with mild distal forearm fracture , without severe cases , loss of body trauma increases the distal radius bone cortex and bone quality .In addition, the transition period from adolescence to adult peak bone mass will fall .Old age men in the history of childhood forearm fracture will increase risk in elderly patients with osteopo-rotic fractures excluding senile women .From the biomechanical point of view with ageing , male cancellous bone loss was mainly due to trabecular thinning , women is mainly to reduce the number of trabecular bone .However , with the increase in age-related loss of cortical bone and cortical porosity seems bigger impact than previously recognized , cortical porosity may increase the risk of brittle fracture in patients.%与年龄相关性脆性骨折是影响当今社会的重大公共卫生健康问题,在生长期骨量的获得和老年相关性骨丢失都是影响其脆性的风险因素。高分辨率外周定量( HRpQCT)的发展增加了对松质骨和皮质骨的微结构变化在整个生命体内改变的认识与评估。研究表明,使用HRpQCT可以看到青少年成长期在前臂远端骨折与骨皮质改变的瞬时增加有关,也包括骨皮质变薄和皮质孔隙度的增加。儿童前臂远端轻度骨折,在不严重的情况下,外伤也增加全身桡骨远端骨皮质和骨质量的亏损。此外,从青少年到

  20. Effects of human aging on patterns of local cerebral glucose utilization determined by the [18F]fluorodeoxyglucose method

    International Nuclear Information System (INIS)

    The [18F]fluorodeoxyglucose (FDG) scan method with positron emission computed tomography was used to determine patterns of local cerebral glucose utilization (LCMRglu) in 40 normal volunteer subjects aged 18 to 78 years. Throughout all the studies, each subject was quiet, without movement, with eyes open and ears unplugged, exposed only to ambient room light and sound. For the entire group, whole brain mean CMRglu was 26.1 +/- 6.1 mumol 100 g-1 min-1 (mean +/- SD, n . 40). At age 78, mean CMRglu was, on the average, 26% less than at age 18, an alteration of the same order as the variance among subjects at any age. The gradual decline of mean CMRglu with advancing age occurred at a faster rate than was reported for mean cerebral oxygen utilization, possibly due to increasingly altered pathways for glucose utilization, or to increasing oxidation of ketone bodies or other alternative substrates. Glucose utilization in the hemispheres was symmetrical and mean CMRglu of overall cortex, caudate, and thalamus was equal in individuals at all ages. The slopes of decline with age were similar when LCMRglu was averaged over zones corresponding to centrum semiovale, caudate, putamen, and frontal, temporal, parietal, occipital, and primary visual cortex. However, the metabolic ratio of superior frontal cortex to superior parietal cortex declined with age, possibly due to selective degeneration of superior frontal cortex or to differences between age groups in the sensory and cognitive response to the study. These results should be useful in distinguishing age from disease effects when the FDG scan method is used

  1. Isotopic age determination in Bergslagen, Sweden. 1

    International Nuclear Information System (INIS)

    This paper is an introduction to a series of short communications 'Isotopic age determinations in Bergslagen, Sweden', which will be submitted to this journal. An earlier paper on K-Ar ages of hornblendes in skarns and metabasites in the Hjulsjoe area has been published elsewhere (Moorman et al., 1982). This joint research project of the ZWO-Laboratory of Isotope Geology and the Geological Institute University of Amsterdam forms part of the research program of the 'Stichting voor Isotopen-Geologisch Onderzoek', supported by the Netherlands Organization for the Advancement of Pure Research (Z.W.O.). (Auth.)

  2. Study to determination the age and extension rate of corals in related to climate change by X-ray

    International Nuclear Information System (INIS)

    The research has been conducted to determine the age and growing rate of corals using x-ray and its correlation with El-nino events and climate change in Kepulauan Seribu. Massive corals Porites Lutea were drilled vertically using pneumatic drilling with 5 cm in diameter. Samples were prepared, x-rayed and analyzed using software Image-J to determine age, linear growth direction and rate. The result shows that average of growth rate of coral in three locations in Kepulauan Seribu is about the same, however the growing rate toward onshore is higher than other locations. Based on the analysis of growing rate, there are two-largest El-Nino events that can be determined related to the period of 1997-1998 and 1982-1983. (author)

  3. Late Pleistocene leopards across Europe - northernmost European German population, highest elevated records in the Swiss Alps, complete skeletons in the Bosnia Herzegowina Dinarids and comparison to the Ice Age cave art

    Science.gov (United States)

    Diedrich, Cajus G.

    2013-09-01

    European leopard sites in Europe demonstrate Early/Middle Pleistocene out of Africa lowland, and Late Pleistocene Asian alpine migrations being driven by climatic changes. Four different European Pleistocene subspecies are known. The final European Late Pleistocene “Ice Age leopard” Panthera pardus spelaea (Bächler, 1936) is validated taxonomically. The skull shows heavy signs of sexual dimorphism with closest cranial characters to the Caucasian Panthera pardus ciscaucasica (Persian leopard). Late Pleistocene leopards were distributed northernmost, up to S-England with the youngest stratigraphic records by skeletons and cave art in the MIS 2/3 (about 32,000-26,000 BP). The oldest leopard painting left by Late Palaeolithics (Aurignacians/Gravettians) in the Chauvet Cave (S-France) allows the reconstruction of the Ice Age leopard fur spot pattern being close to the snow or Caucasian leopards. The last Ice Age glacial leopard habitat was the mountain/alpine boreal forest (not mammoth steppe lowland), where those hunted even larger prey such as alpine game (Ibex, Chamois). Into some lairs, those imported their prey by short-term cave dwelling (e.g. Baumann's Cave, Harz Mountains, Germany). Only Eurasian Ice Age leopards specialized, similar as other Late Pleistocene large felids (steppe lions), on cave bear predation/scavenging partly very deep in caves. In Vjetrenica Cave (Dinarid Mountains, Bosnia Herzegovina), four adult leopards (two males/two females) of the MIS 3 were found about two km deep from the entrance in a cave bear den, near to one cave bear skeleton, that remained articulated in its nest. Leopards died there, partly being trapped by raising water levels of an active ponor stream, but seem to have been killed possibly either, similar as for lions known, in battles with cave bears in several cave bear den sites of Europe (e.g. Baumann's Cave, Wildkirchli Cave, Vjetrenica Cave). At other large cave sites, with overlap of hyena, wolf and dhole dens at

  4. In vitro study on porous silver scaffolds prepared by electroplating method using cellular carbon skeleton as the substrate

    International Nuclear Information System (INIS)

    Porous silver scaffolds, with the porosity ranging from 68% to 81% and the apparent density ranging from 0.4 to 1 g⋅cm−3 were prepared by electroplating method using cellular carbon skeleton as the substrate. The microstructure, mechanical property, cytotoxicity and antibacterial activity of the prepared porous silver scaffold were studied. The present porous silver scaffolds had a highly three-dimensional trabecular porous structure with the porosity and the apparent density close to that of the cancellous bone. Furthermore, the mechanical property such as elastic modulus and yield strength of the porous silver scaffolds were lower than that of commercial available porous Ti and porous Ti alloys but much closer to that of the cancellous bone and porous Ta. In addition, study of in vitro behavior showed that the porous silver scaffold possessed significant antibacterial capability of inhibition of bacterial proliferation and adherence against Staphylococcus aureus and Staphylococcus epidermidis, and little cytotoxicity to Mg-63 cell line and NIH-3T3 cell line. Consequently, the porous silver scaffolds prepared by electrodeposition possess a promising application for bone implants. - Highlights: ► Porous Ag scaffolds were produced by electroplating Ag on cellular carbon skeleton. ► Porous Ag scaffolds have the porosity 68–81% and the apparent density 0.4–1 g⋅cm−3. ► The mechanical property of porous Ag is close to cancellous bone and porous Ta. ► Porous Ag inhibits the proliferation and adherence of S. aureus and S. epidermidis.

  5. Results obtained by quantifying skeleton scintiscanning for the evaluation of primary bone tumours

    International Nuclear Information System (INIS)

    Since the region-of-interest technique can now more frequently be applied with nuclear-medical small computer systems available, this conference paper reports about the use of quantifying scintigraphy for evaluating the extent of uptake of Tc-99m-M.D.P. by the primary bone tumours. The quotients thus determined have been correlated with the histological findings for the most frequent bone tumours, for the purpose of assessing the dignity of a bone tumour by means of the quotients. Radiography, however, still is the most important imaging technique for the diagnosis of primary bone tumours. (orig./MG)

  6. Al/Al2O3 Composite Coating Deposited by Flame Spraying for Marine Applications: Alumina Skeleton Enhances Anti-Corrosion and Wear Performances

    Science.gov (United States)

    Huang, Jing; Liu, Yi; Yuan, Jianhui; Li, Hua

    2014-04-01

    Here we report aluminum-alumina composite coatings fabricated by flame spraying for potential marine applications against both corrosion and wear. Microstructure examination suggested dense coating structures and the evenly distributed alumina splats formed hard skeleton connecting individual Al splats. The anti-corrosion and wear performance of the coatings were enhanced significantly by the addition of alumina. Failure analyses of the coatings after accelerated corrosion testing disclosed the intact alumina skeleton, which prevented further advancement of the corrosion. The results suggest that there is great potential for the cost-effective Al-Al2O3 coatings with tailorable alumina contents for application in the marine environment.

  7. Age dynamics of zinc and iron contents in human hair determined by INAA and ICP-ES

    International Nuclear Information System (INIS)

    Full text: In last decades, the determination of chemical element levels in human hair has been a subject of continual interest in the forensic, clinical, occupational and environmental medicine. Hair has been increasingly used as a monitor for many elements and has been proposed for assessing environmental exposure, nutritional status, and for diagnosis of disease. It has many advantages for assessment over the more traditional kinds of medical objects such as blood and urine because of ease of collection, transport and storage. Also, trace element concentrations in hair samples represent an integrated response over time compared with blood and urine levels, which can rapidly fluctuate in response to variations of nutritional and environmental conditions. The fact that contents of many chemical elements in hair are relatively high also facilitates the analysis. It is known that the result of the hair analysis may not directly relate to the intake amount, nor does it always reflect the amount actually absorbed. Despite these limitations, the analysis of human hair can still provide a basis for estimating ambient exposure to certain elements. The first step in construction of such basis is investigations the national population normal levels of chemical element contents in hair related to sex, age and some other factors under quality control of results. The objectives of this analytical work were to evaluate the reference range of Zn and Fe in adult scalp hair and to evaluate the effect of age and sex on elemental contents. In this study, head hair samples from adult health persons living in or near Obninsk (the small city in rural region 105 km south-west Moscow), were analysed by two methods in three analytical laboratories: instrumental neutron activation analysis (INAA - one laboratory) and atomic emission spectrometry with inductively coupled plasma (ISP-AES - two laboratories). Scalp hair samples were obtained at necropsy from eighty-three cadavers (38 women

  8. The stapl Skeleton Framework

    KAUST Repository

    Zandifar, Mani

    2015-01-01

    © Springer International Publishing Switzerland 2015. This paper describes the stapl Skeleton Framework, a highlevel skeletal approach for parallel programming. This framework abstracts the underlying details of data distribution and parallelism from programmers and enables them to express parallel programs as a composition of existing elementary skeletons such as map, map-reduce, scan, zip, butterfly, allreduce, alltoall and user-defined custom skeletons. Skeletons in this framework are defined as parametric data flow graphs, and their compositions are defined in terms of data flow graph compositions. Defining the composition in this manner allows dependencies between skeletons to be defined in terms of point-to-point dependencies, avoiding unnecessary global synchronizations. To show the ease of composability and expressivity, we implemented the NAS Integer Sort (IS) and Embarrassingly Parallel (EP) benchmarks using skeletons and demonstrate comparable performance to the hand-optimized reference implementations. To demonstrate scalable performance, we show a transformation which enables applications written in terms of skeletons to run on more than 100,000 cores.

  9. Coral skeletons defend against ultraviolet radiation.

    Directory of Open Access Journals (Sweden)

    Ruth Reef

    Full Text Available BACKGROUND: Many coral reef organisms are photosynthetic or have evolved in tight symbiosis with photosynthetic symbionts. As such, the tissues of reef organisms are often exposed to intense solar radiation in clear tropical waters and have adapted to trap and harness photosynthetically active radiation (PAR. High levels of ultraviolet radiation (UVR associated with sunlight, however, represent a potential problem in terms of tissue damage. METHODOLOGY/PRINCIPAL FINDINGS: By measuring UVR and PAR reflectance from intact and ground bare coral skeletons we show that the property of calcium carbonate skeletons to absorb downwelling UVR to a significant extent, while reflecting PAR back to the overlying tissue, has biological advantages. We placed cnidarians on top of bare skeletons and a UVR reflective substrate and showed that under ambient UVR levels, UVR transmitted through the tissues of cnidarians placed on top of bare skeletons were four times lower compared to their counterparts placed on a UVR reflective white substrate. In accordance with the lower levels of UVR measured in cnidarians on top of coral skeletons, a similar drop in UVR damage to their DNA was detected. The skeletons emitted absorbed UVR as yellow fluorescence, which allows for safe dissipation of the otherwise harmful radiation. CONCLUSIONS/SIGNIFICANCE: Our study presents a novel defensive role for coral skeletons and reveals that the strong UVR absorbance by the skeleton can contribute to the ability of corals, and potentially other calcifiers, to thrive under UVR levels that are detrimental to most marine life.

  10. Automated segmentations of skin, soft-tissue, and skeleton, from torso CT images

    Science.gov (United States)

    Zhou, Xiangrong; Hara, Takeshi; Fujita, Hiroshi; Yokoyama, Ryujiro; Kiryu, Takuji; Hoshi, Hiroaki

    2004-05-01

    We have been developing a computer-aided diagnosis (CAD) scheme for automatically recognizing human tissue and organ regions from high-resolution torso CT images. We show some initial results for extracting skin, soft-tissue and skeleton regions. 139 patient cases of torso CT images (male 92, female 47; age: 12-88) were used in this study. Each case was imaged with a common protocol (120kV/320mA) and covered the whole torso with isotopic spatial resolution of about 0.63 mm and density resolution of 12 bits. A gray-level thresholding based procedure was applied to separate the human body from background. The density and distance features to body surface were used to determine the skin, and separate soft-tissue from the others. A 3-D region growing based method was used to extract the skeleton. We applied this system to the 139 cases and found that the skin, soft-tissue and skeleton regions were recognized correctly for 93% of the patient cases. The accuracy of segmentation results was acceptable by evaluating the results slice by slice. This scheme will be included in CAD systems for detecting and diagnosing the abnormal lesions in multi-slice torso CT images.

  11. Analyzer of Spectra for Age Determination (ASAD) - Algorithm and Applications

    OpenAIRE

    Asa'd, Randa

    2014-01-01

    Analyzer of Spectra for Age Determination (ASAD) is a new package that can easily predict the age and reddening of stellar clusters from their observed optical integrated spectra by comparing them to synthesis model spectra. The ages obtained with ASAD are consistent with ages obtained from previous cluster age methods requiring a more rigorous and time-consuming analysis. This package not only provides fast results, but also allows the user to comprehend the accuracy of these results by prov...

  12. 挤出滚圆法制备香青兰黄酮骨架型微丸%Preparation of Dracocephalum moldevica Flavonoids Skeleton-TypePellets by Extrusion Spheronization Method

    Institute of Scientific and Technical Information of China (English)

    李悦; 邢建国; 杨秀; 王新春; 薛桂蓬

    2012-01-01

    Objective: To optimize preparation technology of Dracocephalum moldevica flavonoids skeleton -type pellets by extrusion spheronization method. Method: D. Moldevica flavonoids skeleton-type pellets were prepared by extrusion spheronization Method: Optimal formulation and process was obtained by single factor test and orthogonal design; Micromeritic properties and cumulative in vitro release of pellets were determined. Result:D. Moldevica flavonoids skeleton-type pellets were prepared by extrusion spheronization method were all good of roundness, fluidity and density, product yield was high, in vitro release reached more than 80% in 30 min. Conclusion:D. Moldevica flavonoids skeleton-type pellets were prepared by extrusion spheronization method, this preparation process was simple and feasible, quality of prepared pellets was excellent and product yield was high.%目的:优化挤出滚圆法制备维药香青兰黄酮骨架微丸的制备工艺.方法:用挤出滚圆法制备香青兰黄酮骨架微丸;采用单因素考察和正交设计筛选最优处方和工艺条件;考察微丸的粉体学性质和体外释放度.结果:采用挤出滚圆法制备的香青兰黄酮骨架微丸圆整度、流动性及堆密度均较好,成品收率高,且30 min内体外释放度均达到80%以上.结论:挤出滚圆法制备维药香青兰黄酮骨架微丸,工艺简便易行,制得的微丸质量好,收率高.

  13. Isotopic age determinations in Bergslagen, Sweden: VII

    International Nuclear Information System (INIS)

    Rb-Sr whole-rock analysis of seven samples of the Fellingsbro-type Younger Granite east of Kopparberg gives an age of 1715 +- 50 Ma and an initial 87Sr/86Sr ratio of 0.7046+-0.0026 (errors 95% confidence level). This age falls in the age range determined for the Younger Granites of the Vaermland-Smaaland, Dala and Fellingsbro Groups, 1.74-1.64 Ga. Reliable age data from the Malingsbo-type granites in the Kopparberg area are still lacking, however, so it is uncertain whether they can be included in the Fellingsbro Group of Younger Granites. (orig.)

  14. Determination of the Thermal Expansion Coefficient of Concrete at Early Ages by Using Temperature-stress Testing Machine

    Institute of Scientific and Technical Information of China (English)

    HUO Kaicheng; SHUI Zhonghe; LI Yue

    2006-01-01

    By using the uptodate temperatuer-stress testing machine, the thermal expansion coefficient of concrete at early ages was studied and indicative conclusions were achieved: temperature rising due to hydration heat is not directly correlated with cracking, but the temperature and stress evolution process should be taken into consideration in the same time. Proper chemical admixtures and mineral compositions can improve the mechanical properties of concrete such as thermal expansion coefficient, which is very indicative in practice.

  15. Photogrammetric survey of dinosaur skeletons

    Directory of Open Access Journals (Sweden)

    A. Wiedemann

    1999-01-01

    Full Text Available To derive physiological data of dinosaurs, it is necessary to determine the volume and the surface area of this animals. For this purpose, a detailed survey of reconstructed skeletons is required. The skeletons of three dinosaurs in the Museum für Naturkunde in Berlin and two skeletons in the Museum d'Histoire Naturelle in Paris have been surveyed using stereo photogrammetry. Two of the Berlin skeletons were also surveyed with the close range laser scanners of the Institut für Navigation of the Universität Stuttgart. Both data acquisition techniques require a geodetic control network as a geometric reference system. The surveying methods used, together with results of mathematical approaches for the determination of the volume and surface of the animals are presented in this paper. Zur Herleitung physiologischer Daten der Dinosaurier ist es erforderlich, zunächst Volumen und Oberfläche ihres Körpers zu bestimmen. Dazu wurde eine detaillierte Vermessung rekonstruierter Skelette durchgeführt. Die Skelette dreier Saurier im Museum für Naturkunde in Berlin und zweier im Museum d'Histoire Naturelle in Paris wurden stereophotogrammetrisch vermessen. Bei zwei der Berliner Skelette wurden zusätzlich die Laserscanner des Instituts für Navigation der Universität Stuttgart eingesetzt. Beide Datenerfassungstechniken benötigen ein Paßpunktfeld als geometrisches Referenzsystem. Die verwendeten Vermessungsmethoden, die mathematischen Ansätze für die Berechnung von Volumina und Oberflächen und die Ergebnisse werden in diesem Aufsatz vorgestellt. doi:10.1002/mmng.1999.4860020108

  16. Age determination enhanced by embryonic foot bud and foot plate measurements in relation to Carnegie stages, and the influence of maternal cigarette smoking

    DEFF Research Database (Denmark)

    Lutterodt, M C; Rosendahl, M; Yding Andersen, C;

    2009-01-01

    habits, and delivered a urine sample for cotinine analysis. Embryonic age was evaluated by vaginal ultrasound measurements and by post-termination foot length and compared with the Carnegie stages. RESULTS: Foot bud and foot plate were defined and measured as foot length in embryos aged 35-47 days p......BACKGROUND: Reliable age determination of first-trimester human embryos and fetuses is an important parameter for clinical use and basic science. Age determination by ultrasound or morphometric parameters of embryos 4-6 weeks post conception (p.c.) have been questioned, and more accurate methods.......c. (range 0.8-2.1 mm). In embryos and fetuses aged 41-69 days p.c., heel-toe length was measured (range 2.5-7.5 mm). We found a significant linear correlation between foot length and age. Morphology of the feet was compared visually with the Carnegie collection, and we found that the mean ages of the two...

  17. Determination of hydrogen concentration in a-Si and a-Ge layers by elastic recoil detection analysis

    International Nuclear Information System (INIS)

    Compete text of publication follows. Hydrogenated amorphous Si and Ge films are of current interest in academic and industrial research due to their unique physical properties and important applications. The incorporation of hydrogen in the amorphous network is an accepted means for reducing the density of defect states in the midgap. The passivation of dangling-bonds leads to a significant improvement in the electronic and optical properties of these layers. However, hydrogen is also suspected to degrade the performance of amorphous Si and Ge material and devices. Several studies related to hydrogen motion have been proposed to explain the light and thermal degradation effect in these layers. Thus to improve the performance and reliability of these devices, it is crucially important to understand the role of hydrogen in amorphous layers. In our previous works the structural changes of hydrogenated a-Si/Ge multilayers as a function of annealing condition was investigated. It was shown that during annealing the samples underwent significant structural changes. Due to the fast out-diffusion of hydrogen from the layers prepared with high (6 ml/min) H2 flow rate, bubbles and craters were created on the surface. However, in the multilayer samples prepared with hydrogen flow rate lower than 6 ml/min the macroscopic degradation by formation bubbles and craters was more moderated. The diffusion measurement shows that in these samples the structural degradation and intermixing of layers was slower than in the non-hydrogenated samples. As it was suggested the hydrogen can inactivate the dangling bonds of amorphous layers and, as a result of this, the intermixing slows down. It was also predicted that the hydrogen first released from the Ge layers because of the lower binding energy. In this work, we have studied the individual a-Si and a-Ge hydrogenated layers prepared by RF sputtering on Si (100) substrates. The absolute value of atomic content of the H was determined by

  18. Tensor Network Skeletonization

    CERN Document Server

    Ying, Lexing

    2016-01-01

    We introduce a new coarse-graining algorithm, tensor network skeletonization, for the numerical computation of tensor networks. This approach utilizes a structure-preserving skeletonization procedure to remove short-range correlations effectively at every scale. This approach is first presented in the setting of 2D statistical Ising model and is then extended to higher dimensional tensor networks and disordered systems. When applied to the Euclidean path integral formulation, this approach also gives rise to new efficient representations of the ground states for 1D and 2D quantum Ising models.

  19. Forensic quest for age determination of bloodstains.

    Science.gov (United States)

    Bremmer, Rolf H; de Bruin, Karla G; van Gemert, Martin J C; van Leeuwen, Ton G; Aalders, Maurice C G

    2012-03-10

    Bloodstains at crime scenes are among the most important types of evidence for forensic investigators. They can be used for DNA-profiling for verifying the suspect's identity or for pattern analysis in order to reconstruct the crime. However, until now, using bloodstains to determine the time elapsed since the crime was committed is still not possible. From a criminalistic point of view, an accurate estimation of when the crime was committed enables to verify witnesses' statements, limits the number of suspects and assesses alibis. Despite several attempts and exploration of many technologies during a century, no method has been materialized into forensic practice. This review gives an overview of an extensive search in scientific literature of techniques that address the quest for age determination of bloodstains. We found that most techniques are complementary to each other, in short as well as long term age determination. Techniques are compared concerning their sensitivity for short and long term ageing of bloodstains and concerning their possible applicability to be used on a crime scene. In addition, experimental challenges like substrate variation, interdonor variation and environmental influences are addressed. Comparison of these techniques contributes to our knowledge of the physics and biochemistry in an ageing bloodstain. Further improvement and incorporation of environmental factors are necessary to enable age determination of bloodstains to be acceptable in court. PMID:21868178

  20. Connection Skeleton Extraction Based on Contour Connectedness

    Institute of Scientific and Technical Information of China (English)

    CHEN Mang; LIU Yun-cai

    2008-01-01

    A stable skeleton is very important to some applications such as vehicle navigation, object represent and pattern recognition. The connection skeleton is just one that not only can be computed stably but also can figure the connectivity structure of contour. A new method named continuous connectivity detection and a new model named approximate regular polygon (ARP) were proposed for connection skeleton extraction. Both the method and the model were tested by the real maps of road network including flyovers, interchanges and other common object contours. Satisfactory results were obtained.

  1. Stable Isotope Analysis of Extant Lamnoid Shark Centra: A New Tool in Age Determination?

    Science.gov (United States)

    Labs, J.

    2003-12-01

    The oxygen isotopes of fourteen vertebral centra from ten extant lamnoid sharks (including Carcharodon carcharias [great white], Isurus paucus [longfin mako], and Isurus oxyrinchus [shortfin mako]) were sampled and measured along the growth axis to determine the periodicity of incremental growth represented in the centra. As part of the internal (endochondral) skeleton, shark centra are composed initially of hyaline cartilage, which then secondarily ossifies during ontogeny forming calcified hydroxyapatite bone. The incremental growth of shark centra forms definite growth rings, with darker denser portions being deposited during slower growth times (i.e., winter) and lighter portions being deposited during more rapid growth (i.e., summer). Thus, shark centra, whether they are extant or extinct, are characterized by clearly delineated incremental growth couplets. The problem with this general rule is that there are several factors in which the growth of these couplets can vary depending upon physical environment (including temperature and water depth), food availability, and stress. The challenge for paleobiological interpretations is how to interpret the periodicity of this growth. It can generally be assumed that these bands are annual, but it is uncertain the extent to which exceptions to the rule occur. Stable isotopic analysis provides the potential to independently determine the periodicity of the growth increments and ultimately the ontogenetic age of an individual.

  2. Radiation load in determining bone age

    International Nuclear Information System (INIS)

    The determination of the bone age in children is based on X-ray of the left wrist. By means of the dosimetric device 'Robotron 2300' it is shown that the average surface dose for single X-ray is about 49.105 Gy. The execution of single X-ray is well-grounded and the conditions for it are specified: blending of the object and shielding of the gonads and the whole body with a lead rubber as well as immobilizing of the hand with a specially made appliance. The risk of radiation injury during the study is practically negligible. Having in mind the significance of the problems which could be solved using the results of such a study, the benefit/harm relationship is in favour of broader use of the method. 12 refs., 1tab. described

  3. The taphonomy of fallow deer (Dama dama) skeletons from Denmark and its bearing on the pre-Weichselian occupation of northern Europe by humans

    DEFF Research Database (Denmark)

    Egeland, Charles P.; Nielsen, Trine Kellberg; Byø, Malene;

    2014-01-01

    various techniques to the Eemian interglacial (MIS 5e), this site has yielded the remains of several purportedly butchered fallow deer (Dama dama). Taphonomic reanalysis of the remains from Hollerup and a handful of other Eemian-aged fallow deer skeletons cast doubt on the interpretation that they were...... humanly modified. We place this revised conclusion into the wider context of human settlement of southern Scandinavia during the Eemian. Other claims of Neandertal presence in the region rest on candidate Middle Paleolithic artifacts, all of which derive from surface contexts. With the fallow deer...

  4. Development of a SPME-GC-MS method for the determination of volatile compounds in Shanxi aged vinegar and its analytical characterization by aroma wheel.

    Science.gov (United States)

    Zhu, Hong; Zhu, Jie; Wang, Lili; Li, Zaigui

    2016-01-01

    A solid-phase microextraction followed by gas chromatography-mass spectrometry method was developed to determine the volatile compounds in Shanxi aged vinegar. The optimal extraction conditions were: 50 °C for 20 min with a PDMS/DVB fiber. This analytical method was validated and showed satisfactory repeatability (0.5 %volatile compounds. According to the calculation of odor activity value, 19 volatile compounds were identified as aroma-active compounds. Among them, propanoic acid, acetic acid, trimethyl-oxazole, butanoic acid, acetoin, 3-methylbutanoic acid and furfural were the most powerful odorants. The aroma wheel of Shanxi aged vinegar showed that the classes of sensory descriptors are first fatty and roasty, next woody and nutty and minor fruity and floral. Principal component analysis enabled us to investigate dissimilarity/similarity of Shanxi aged vinegar sample of different raw material and ageing time. PMID:26787940

  5. Analyzer of Spectra for Age Determination (ASAD) - Algorithm and Applications

    CERN Document Server

    Asa'd, Randa

    2014-01-01

    Analyzer of Spectra for Age Determination (ASAD) is a new package that can easily predict the age and reddening of stellar clusters from their observed optical integrated spectra by comparing them to synthesis model spectra. The ages obtained with ASAD are consistent with ages obtained from previous cluster age methods requiring a more rigorous and time-consuming analysis. This package not only provides fast results, but also allows the user to comprehend the accuracy of these results by providing surface plots and spectral plots for all combinations of observations and models. ASAD is available for download on the Web and can be immediately used on both Mac and Windows.

  6. Simultaneous in-situ determination of U-Pb age and trace elements in zircon by LA-ICP-MS in 20 μm spot size

    Institute of Scientific and Technical Information of China (English)

    LIU XiaoMing; GAO Shan; DIWU ChunRong; YUAN HongLin; HU ZhaoChu

    2007-01-01

    Simultaneous in-situ determination of U-Pb agea and 20 trace elements of three international zircon standards (91500, GJ1 and TEMORA 1) and one laboratory zircon standard (SK10-2) separated from Cenozoic fine-grained gabbro was carried out on quadrupole ICP-MS equipped with 193 nm excimer laser in 20 μm spot size. The weighted mean 208Pb/238U ages of g1500, GJ1 and TEMORA 1 are 1064.4±4.8 Ma (2σ), 603.2±2.4 Ma (2σ) and 418.2±2.4 Ma (2σ), respectively. The relative standard deviations (RSDs) of 206Pb/238U ages (2σ) are less than 2.2% for single measurements and 0.6% for weighted means. The obtained weighted mean 206Pb/238U ages of three atandard zircons agree with the recommended values within 2σσerror. The weighted mean 206Pb/238U age of SK10-2 is 31.42±0.25 Ma (2σ)and the RSDs of 206Pb/238U ages (2σ) are between 2.4% and 5.7% for single measurements and less than 0.8% for weighted mean. The obtained weighted mean 206Pb/238U age is in good agreement with the age obtained by Yuan (2004). Trace element concentrations of NIST612 and NIST614 obtained under the same LA-ICP-MS operating conditions agree with the recommended values within analytical error. The results indicate that it is possible to measure U-Pb age and trace elements aimultaneously by LA-ICP-MS in a small spot size of 20 μm.

  7. Age determination using ultrasonography in young football players

    Directory of Open Access Journals (Sweden)

    Mehdi Karami

    2014-01-01

    Full Text Available Background: Increasing of age cheating in sports makes problems to athletes comparable to taking illegal substances. Current method used by AFC and FIFA is applying MRI of growth plate of distal of radius to determine the bone age. This study was designed to evaluate the diagnostic accuracy of ultrasonography in bone age determination by measuring the width of growth plate in distal of radius, and comparing it with identity documents. Materials and Methods: The study was conducted from September to December 2009 in the Department of Radiology at Al-Zahra University Hospital, Isfahan, Iran. Ultrasonography was done for 82 (15-20 years old young professional football players and results were compared with identity documents (such as National ID card. Young football players were divided into three age categories: 16 years old, 17 years old, and 18 years old. Receiver Operator Characteristics (ROC curves for discriminant values and sensitivity and specificity were analyzed. Results: Cut-off point was set for each group, based on the width of the growth plate, and negative test was defined as subjects < cut-off point, showing subjects over the defined age in each group. ROC curve analysis demonstrates consistently acceptable diagnostic sensitivity and specificity values in age determination of each group. Conclusions: The overall predictive accuracy of ultrasonography, as described by the area under the ROC curve, was high for determination of bone age. It has an acceptable sensitivity and specificity to use for determination of age in sport competitions, and has the capability to become the screening test for age determination, especially because it is inexpensive and without any risk of radiation. It seems to be comparable with MRI in age determination.

  8. Determination on the mineral salt content of the peripheral skeleton (ulna and calcaneus) in thyroid patients using 125I gamma-radiation absorption measurement

    International Nuclear Information System (INIS)

    The bone mineral salt content (BMC) has been determined in this work for 69 female and 14 male hyperthyroid patients and 13 euthyroid adenoma patients by means of I125 gamma-radiation absorption measurement. It could be seen by comparison to healthy patients that hyperthyroid patients lie statistically significantly below the corresponding age and sex standard values, whilst the euthyroid adenoma female patients' values are found in the BMC normal range. It was furthermore shown that the menopause did not essentially influence the BMC values of Ulna and calcaneus. A further chapter treats the dependence of the BMC values on the hyperthyroidosis duration. Queries on whether the height of the BMC values depend on the f T4 index were treated, as well as whether patients showing different extents of clinical hyperthyroid indications, statistically significantly differ even with average BMC. A comparison of the average BMC values of pretreated and untreated hyperthyroidosis patients was made. (orig./MG)

  9. Computational tool for phase-shift calculation in an interference pattern by fringe displacements based on a skeletonized image

    Science.gov (United States)

    Rivera-Ortega, Uriel; Pico-Gonzalez, Beatriz

    2016-01-01

    In this manuscript an algorithm based on a graphic user interface (GUI) designed in MATLAB for an automatic phase-shifting estimation between two digitalized interferograms is presented. The proposed algorithm finds the midpoint locus of the dark and bright interference fringes in two skeletonized fringe patterns and relates their displacements with the corresponding phase-shift. In order to demonstrate the usefulness of the proposed GUI, its application to simulated and experimental interference patterns will be shown. The viability of this GUI makes it a helpful and easy-to-use computational tool for educational or research purposes in optical phenomena for undergraduate or graduate studies in the field of physics.

  10. Skeleton scintigraphy in trauma

    International Nuclear Information System (INIS)

    Skeletal trauma is common and presents both an opportunity and a problem in skeletal scintigraphy. The opportunity arises in the ability of skeletal scintigraphy to demonstrate abnormalities early after direct trauma. It is well recognized that the early detection of fractures in some sites cannot be reliably achieved by standard radiography, especially in the femoral neck and scaphoid bone. The problem comes in recognizing the effects of skeletal trauma when using skeletal scintigraphy for another purpose, such as the detection of metastatic disease. iatrogenic trauma to either the skeleton or soft tissues may be manifest scintigraphic ally. For example Craniotomy typically leaves a rim pattern at the surgical margin. Rib Retraction during thoracotomy can elicit periosteal reaction. Areas of the skeletal receiving curative levels of ionizing radiation (typically 4000 rads or greater) characteristically demonstrate decreased uptake within 6 months to 1 year after therapy. The generally high sensitivity of the skeletal scintigraphy seems to make it an ideal survey test in cases of suspected child abuse especially in which radiographs are unrevealing. Because of difficulties in obtaining a history of trauma from a preschool child or even eliciting a satisfactory description of the location and nature of the pain, skeletal scintigraphy provides a simple and reliable investigation in these children. Subtle trauma, such as that from stress fractures is often difficult to visualize on a plain radiograph. Skeletal scintigraphy is frequently positive at the time of clinical presentation. Skeletal scintigraphy is exquisitely sensitive to the remodeling process and typically shows abnormalities 1 to 2 weeks or more before the appearance of radiographic changes in stress fractures. The periosteal reaction can be visualized within hours of the injury. Insufficiency and fatigue fractures such as vertebral compression fracture, which is probably the most common consequence of

  11. Foetal age determination and development in elephants.

    Science.gov (United States)

    Hildebrandt, Thomas; Drews, Barbara; Gaeth, Ann P; Goeritz, Frank; Hermes, Robert; Schmitt, Dennis; Gray, Charlie; Rich, Peter; Streich, Wolf Juergen; Short, Roger V; Renfree, Marilyn B

    2007-02-01

    Elephants have the longest pregnancy of all mammals, with an average gestation of around 660 days, so their embryonic and foetal development have always been of special interest. Hitherto, it has only been possible to estimate foetal ages from theoretical calculations based on foetal mass. The recent development of sophisticated ultrasound procedures for elephants has now made it possible to monitor the growth and development of foetuses of known gestational age conceived in captivity from natural matings or artificial insemination. We have studied the early stages of pregnancy in 10 captive Asian and 9 African elephants by transrectal ultrasound. Measurements of foetal crown-rump lengths have provided the first accurate growth curves, which differ significantly from the previous theoretical estimates based on the cube root of foetal mass. We have used these to age 22 African elephant foetuses collected during culling operations. Pregnancy can be first recognized ultrasonographically by day 50, the presumptive yolk sac by about day 75 and the zonary placenta by about day 85. The trunk is first recognizable by days 85-90 and is distinct by day 104, while the first heartbeats are evident from around day 80. By combining ultrasonography and morphology, we have been able to produce the first reliable criteria for estimating gestational age and ontological development of Asian and African elephant foetuses during the first third of gestation. PMID:17164195

  12. A neglected requirement for optimizing treatment of age-related osteoporosis: Replenishing the skeleton's base reservoir with net base-producing diets.

    Science.gov (United States)

    Sebastian, Anthony; Frassetto, Lynda A

    2016-06-01

    Osteoporosis is a disorder of bone in which the mass of the bone is reduced and the bone's architecture at the microscopic level is disordered. Together those abnormalities predispose affected individuals to experience fractures despite only minimal trauma (i.e., fragility fractures). Age related osteoporosis is a common type of osteoporosis that occurs with aging in both men and women usually beginning after the age of peak bone mass. Research has found that the disorder can be partially reversed by reducing the net amount of acid that is produced when consuming typical Western diets. However, the amelioration that results has not been so dramatic or so consistent that physicians have adopted the procedure as part of the standard treatment for age-related osteoporosis. We propose that reducing the net acid load from the diet is not sufficient to reverse age related osteoporosis because it fails to supply base needed to restore the large amount of base in bone that had been lost by reacting with the net acid load of the diet that had been consumed for years or decades. Reducing the net acid load from the diet might be expected to have little ameliorative effect or merely slow the progression of the disorder. We hypothesize that both to restore osteoporotic bone to, or nearly to, its pre-disease state, as well as to eliminate the risk of fragility fractures, requires consuming diets that produce net amounts of base to restore the base lost from years to decades of consuming diets that produce net amounts of acid. We hypothesize also that the excess base and attendant subclinical metabolic alkalosis will both stimulate the cellular process of bone formation and suppress the cellular process of bone resorption, and thereby implement the restorative process. PMID:27142156

  13. Acid-Base and the Skeleton

    Science.gov (United States)

    Bushinsky, David A.

    2008-09-01

    Chronic metabolic acidosis increases urine calcium (Ca) excretion in the absence of a concomitant increase in intestinal Ca absorption resulting in a net loss of total body. The source of this additional urine Ca is almost certainly the skeleton, the primary reservoir of body Ca. In vitro metabolic acidosis, modeled as a primary reduction in medium bicarbonate concentration, acutely (24 h) cell-mediated mechanisms predominate. In cultured neonatal mouse calvariae, acidosis-induced, cell-mediated Ca efflux is mediated by effects on both osteoblasts and osteoclasts. Metabolic acidosis inhibits extracellular matrix production by osteoblasts, as determined by measurement of collagen levels and levels for the non-collagenous matrix proteins osteopontin and matrix gla protein. Metabolic acidosis upregulates osteoblastic expression of RANKL (Receptor Activator of NFκB Ligand), an important osteoclastogenic and osteoclast-activating factor. Acidosis also increases osteoclastic activity as measured by release of β-glucuronidase, an enzyme whose secretion correlates with osteoclast-mediated bone resorption.

  14. Biological psychological and social determinants of old age: Bio-psycho-social aspects of human aging

    Directory of Open Access Journals (Sweden)

    Małgorzata Dziechciaż

    2014-11-01

    Full Text Available Biological psychological and social determinants of old age: Bio-psycho-social aspects of human aging. The aging of humans is a physiological and dynamic process ongoing with time. In accordance with most gerontologists’ assertions it starts in the fourth decade of life and leads to death. The process of human aging is complex and individualized, occurs in the biological, psychological and social sphere. Biological aging is characterized by progressive age-changes in metabolism and physicochemical properties of cells, leading to impaired self-regulation, regeneration, and to structural changes and functional tissues and organs. It is a natural and irreversible process which can run as successful aging, typical or pathological. Biological changes that occur with age in the human body affect mood, attitude to the environment, physical condition and social activity, and designate the place of seniors in the family and society. Psychical ageing refers to human awareness and his adaptability to the ageing process. Among adaptation attitudes we can differentiate: constructive, dependence, hostile towards others and towards self attitudes. With progressed age, difficulties with adjustment to the new situation are increasing, adverse changes in the cognitive and intellectual sphere take place, perception process involutes, perceived sensations and information received is lowered, and thinking processes change. Social ageing is limited to the role of an old person is culturally conditioned and may change as customs change. Social ageing refers to how a human being perceives the ageing process and how society sees it.

  15. Comparison of detection rate of osteoporosis in different sex,age and skeleton location%不同性别、年龄及不同骨骼部位骨质疏松检出率的比较

    Institute of Scientific and Technical Information of China (English)

    詹志伟; 裴育; 杜瑞琴; 陈国昌; 邵伟庆; 崔志辉

    2005-01-01

    股骨颈和大转子 BMD有明显正相关( r=0.306,0.329,0.338,P< 0.05). 结论 : OP的检出率随骨骼测量部位和年龄的变化而变化.正确认识和评价这些客观现象,对 OP的诊治具有重要意义.%BACKGROUND:Bone mineral density(BMD) is still regarded as the standard of early diagnosis and treatment of osteoporosis(OP) at present.But it is found in detection that different sex,age and skeleton location have different OP detection rate,so it is necessary to analyze the difference. OBJECTIVE:To compare the difference of OP detection rate at different skeleton location between males and females with the increase of age. DESIGN:A cross-sectional study taking patients as the subjects. SETTING:Endocrine department of an artillery general hospital of Chinese PLA. PARTICIPANTS:A total of 147 patients,including 54 males and 93 females, aged from 50 to 78 years old,who were hospitalized in our outpatient clinic from September 2000 to January 2002,were selected and divided into 3 groups according to age,50 to 59 years old group (n=46,13 males and 33 females),60 to 69 years old group (n=66,26 males and 40 females) and 70 to 79 years old group (n=35,15 accordance with the OP diagnostic criteria recommended by WHO[1]. Exclusive criterion: secondary OP patients caused by chronic disease of liver,kidney, heart, and gastrointestinal tract and some endocrine disease such as diabetes,hyperthyroidism and so on. INTERVENTIONS:Every subject filled in the history questionnaire in detail.Height and body mass were measured accurately and body mass index(BMI) was calculated (kg/m2).A new type of Norland Excell plus dual-energy X-ray absorptiometry(DEXA) was used to detect BMD(g/cm2) of L2- 4 and proximate femur(neck of femur, Ward's triangle,greater trochanter).The detected values were compared with the normal data of young adults of the same sex and the T value(SD) was obtained. RESULTS:OP in lumber vertebra was predominant in female climacteric(χ 2=10.14,P< 0.01),and the detection rate of

  16. Determining optimum aging time using novel core flooding equipment

    DEFF Research Database (Denmark)

    Ahkami, Mehrdad; Chakravarty, Krishna Hara; Xiarchos, Ioannis;

    2016-01-01

    New methods for enhanced oil recovery are typically developed using core flooding techniques. Establishing reservoir conditions is essential before the experimental campaign commences. The realistic oil-rock wettability can be obtained through optimum aging of the core. Aging time is affected by...... optimum aging time regardless of variations in crude oil, rock, and brine properties. State of the art core flooding equipment has been developed that can be used for consistently determining the resistivity of the coreplug during aging and waterflooding using advanced data acquisition software. In the...

  17. Determination of the seric levels of follicle-stimulating hormone, lutein hormone and testosterone in Nellore bovine at different ages, by means of radioimmunoanalysis

    International Nuclear Information System (INIS)

    One hundred male bovines, Nellore breed, coming from the region of Botucatu, State of Sao Paulo, Brazil, were in this research. The animals were distributed into five groups, according to their average age, as follows: 6.25, 9.50, 20.3, 29.7 and 61.1 months, and raised under range conditions. Blood samples were collected from the jugular vein, two and half to three hours after semen collection. Harmone concentrations were determined by radioimmunoassay (RIA). The mean values for the biochemical tests carried out with the serum samples were: 4.70+-1.15 mUI/ml, CV= 24.4% for FSH; 4.98+-0.99 mUI/ml, CV= 19.86% for LH, and 2.78+-3.68ng/ml, CV= 132.48% for testosterone. The analysis of variance showed significant effect (P<0.05) of the age grade on the traits studied. (author)

  18. Skeleton castings dynamic load resistance

    OpenAIRE

    M. Cholewa; J. Szajnar; T. Szuter

    2013-01-01

    Purpose: The article is to show selected results of research in a field of new type of cast spatial composite reinforcements. This article shows skeleton casting case as a particular approach to continuous, spatial composite reinforcement.Design/methodology/approach: The research is concerning properties of cast spatial microlattice structures called skeleton castings. In this paper results of impact test of skeleton casting with octahedron elementary cell were shown. The selection of interna...

  19. Induction of caspase-8 and death receptors by a new dammarane skeleton from the dried fruits of Forsythia koreana.

    Science.gov (United States)

    Hawas, Usama W; Gamal-Eldeen, Amira M; El-Desouky, Samy K; Kim, Young-Kyoon; Huefner, Antje; Saf, Robert

    2013-01-01

    A new naturally occurring compound based on the dammarane skeleton, i.e. cabralealactone 3-acetate-24-methyl ether, was isolated from the aqueous methanolic extract of Forsythia koreana fruits, along with eight known compounds: cabralealactone 3-acetate, ursolic acid, arctigenin, arctiin, phillyrin, rutin, caffeic acid, and rosmarinic acid. The identification of the isolated compounds was based on their spectral analysis including: HREI-MS, 1D and 2D NMR spectroscopy. The selected compounds and the aqueous methanolic extract were evaluated for their cytotoxic activity against human solid tumour cell lines. Cabralealactone 3-acetate-24-methyl ether and ursolic acid were found to be active against human breast cancer cells (MCF-7). The cytotoxicity was associated with the activation of caspase-8, the induction of the death receptors DR4 and DR5, as well as DNA fragmentation, and was thus due to apoptosis rather than necrosis. PMID:23659170

  20. Automated Determination of Bone Age in a Modern Chinese Population

    International Nuclear Information System (INIS)

    Rationale and Objective. Large studies have previously been performed to set up a Chinese bone age reference, but it has been difficult to compare the maturation of Chinese children with populations elsewhere due to the potential variability between raters in different parts of the world. We re-analysed the radiographs from a large study of normal Chinese children using an automated bone age rating method to establish a Chinese bone age reference, and to compare the tempo of maturation in the Chinese with other populations. Materials and Methods. X-rays from 2883 boys and 3143 girls aged 2–20 years from five Chinese cities, taken in 2005, were evaluated using the BoneXpert automated method. Results. Chinese children reached full maturity at the same age as previously studied Asian children from Los Angeles, but 0.6 years earlier than Caucasian children in Los Angeles. The Greulich-Pyle bone age method was adapted to the Chinese population creating a new bone age scale BX-China05. The standard deviation between BX-China05 and chronologic age was 1.01 years in boys aged 8–14, and 1.08 years in girls aged 7–12. Conclusion. By eliminating rater variability, the automated method provides a reliable and efficient standard for bone age determination in China

  1. Age of Cu-Au mineralisation, Cloncurry district, eastern Mt Isa Inlier, Queensland, as determined by 40Ar/39Ar dating

    International Nuclear Information System (INIS)

    The 40Ar/39Ar dating of alteration biotite. muscovite and amphibole from a number of post-peak metamorphic Cu-Au deposits and alteration systems in the Cloncurry district. north Queensland has determined the timing of mineralisation and hydrothermal activity. Alteration biotite from the Ernest Henry Cu-Au, Starra Au-Cu, and Mt Elliott Cu-Au deposits, sericite associated with hematite breccias in the Wimberu Granite, muscovite from an albitite pipe that intrudes the Gilded Rose Breccia. And sericite from a granitoid near the Osborne Cu-Au deposit. yield ages which are broadly contemporaneous with the late ca 1510-1485 Ma phases of the Williams and Naraku Batholiths. Hornblende and biotite alteration, which pre-date Cu-Au mineralisation at Osborne. give a maximum age of ca 1540 Ma for the deposit. which is also a probable minimum age for peak metamorphism. Metamorphic minerals from the vicinity of Osborne yield dates which are significantly older (ca 1590-1570 Ma) than those from the hydrothermal phases. Dating by the K-Ar method of red. Hematitic K-feldspars which are regionally common in the Cloncurry district was not effective as the mineral yields ages up to 300 million years younger than coexisting alteration sericite. The 40Ar/39Ar age spectra obtained from most hydrothermal phases in the Eastern Fold Belt. Mt Isa Inlier commonly contain flat parts which comprise a large proportion of the released gas and are indicative of rapid cooling through the temperature of partial closure to Ar diffusion for the respective minerals. Copyright (1998) Blackwell Science Asia

  2. Isotopic age determinations in Bergslagen, Sweden. IV

    International Nuclear Information System (INIS)

    Rb-Sr whole-rock isotope analyses of ten samples of Graengen granite yield a best-fit line corresponding to an age of 1663 +- 51 Ma with an initial 87Sr/86Sr ratio of 0.70844 +- 0.00578. Four samples of Tallaasberget granite give a best-fit line corresponding to an age of 1639 +- 185 Ma with an initial 87Sr/86Sr ratio of 0.70191 +- 0.04241. Isochron relationships appear disturbed by the low-grade retrograde metamorphism which has affected the granites. Taking account of the limits of error it is suggested that the Graengen and Tallaasberget granites in the Hjulsjoe region, Bergslagen, Central Sweden, are coeval with the 1.7-1.6 Ga granites of the Smaaland and Vaermland Groups in S and SW Sweden. (Auth.)

  3. What determines hatchling weight: breeder age or incubated egg weight?

    OpenAIRE

    AB Traldi; Menten JFM; CS Silva; PV Rizzo; PWZ Pereira; J Santarosa

    2011-01-01

    Two experiments were carried out to determine which factor influences weight at hatch of broiler chicks: breeder age or incubated egg weight. In Experiment 1, 2340 eggs produced by 29- and 55-week-old Ross® broiler breeders were incubated. The eggs selected for incubation weighed one standard deviation below and above average egg weight. In Experiment 2, 2160 eggs weighing 62 g produced by breeders of both ages were incubated. In both experiments, 50 additional eggs within the weight interval...

  4. Determination of hydrogen concentration in a-Si and a-Ge layers by elastic recoil detection analysis

    OpenAIRE

    Kh?nh, Nguyen Quoc; Csik, Attila; Serenyi, Miklos; Erd?lyi, Zolt?n; Beke, Dezső L?szl?; Frigeri, Cesare

    2010-01-01

    Hydrogenated amorphous Si and Ge films are of current interest in academic and industrial research due to their unique physical properties and important applications. The passivation of dangling-bonds leads to a significant improvement in the electronic properties by adding hydrogen into these layers. The hydrogen content in these layers is also an important factor deciding the density and the optical band gap. However, hydrogen is also suspected to degrade the performance of amorphous Si and...

  5. Anterior Cruciate Ligament Injuries in Growing Skeleton

    OpenAIRE

    AlHarby, Saleh W.

    2010-01-01

    Anterior cruciate ligament (ACL) injuries in the adult patients are thoroughly studied and published in orthopedic literature. Until recently, little was known about similar injuries in skeletally growing patients. The more frequent involvement of this age group in various athletic activities and the improved diagnostic modalities have increased the awareness and interest of ACL injuries in skeletally immature patients. ACL reconstruction in growing skeleton is controversial and carries some ...

  6. Determination of the age of research-reactor fuel rods

    International Nuclear Information System (INIS)

    It is demonstrated that a previously developed method for non-destructive, gamma-spectrometric age determination of uranium can be successfully used to determine the age of research-reactor fuel rods. It relies on measuring the daughter/parent activity ratio 214Bi/234U by low-background, high-resolution gamma-spectrometry using intrinsic efficiency calibration. The method does not require the use of any reference materials nor the use of an efficiency-calibrated geometry, and in many cases it could be applied by safeguards inspectors even on the site of the inspection. (author)

  7. 面颅种族判定的测量研究%Racial identification of the facial skeleton by measurement

    Institute of Scientific and Technical Information of China (English)

    张志敏; 张继宗; 高冲

    2011-01-01

    Through introducing and criticizing the development of racial identification from the facial skeleton all over the world, we find viscerocranium have more advantage than palate and mandible in racial identification. So our Chinese racial identification should enhance viscerocranium's study.%通过对国内外面颅种族判定测量研究现状的回顾和评析,指出目前尚没有进行中国黄种人面颅测量种族判定的有效方法.在已进行的面颅种族判定测量研究中,上面部指标的种族判定效果最好,而上腭区和下颌骨指标的种族判定效果较差.所以对于中国黄种人面颅种族判定的测量研究应当更多借鉴上面部的研究成果.

  8. Age determination of subdural hematomas: survey among radiologists.

    Science.gov (United States)

    Postema, F A M; Sieswerda-Hoogendoorn, Tessa; Majoie, C B L M; van Rijn, R R

    2014-08-01

    Abusive head trauma is a severe form of child abuse. One important diagnostic finding is the presence of a subdural hematoma. Age determination of subdural hematomas is important to relate radiological findings to the clinical history presented by the caregivers. In court this topic is relevant as dating subdural hematomas can lead to identification of a suspect. The aim of our study is to describe the current practice among radiologists in the Netherlands regarding the age determination of subdural hematomas in children. This is a cross-sectional study, describing the results of an online questionnaire regarding dating subdural hematomas among pediatric and neuro-radiologists in the Netherlands. The questionnaire consisted of sociodemographic questions, theoretical questions and eight pediatric cases in which the participants were asked to date subdural hematomas based on imaging findings. Fifty-one out of 172 radiologists (30 %) filled out the questionnaire. The percentage of participants that reported it was possible to date the subdural hematoma varied between 58 and 90 % for the eight different cases. In four of eight cases (50 %), the age of the subdural hematoma as known from clinical history fell within the range reported by the participants. None of the participants was "very certain" of their age determination. The results demonstrate that there is a considerable practice variation among Dutch radiologists regarding the age determination of subdural hematomas. This implicates that dating of subdural hematomas is not suitable to use in court, as no uniformity among experts exists. PMID:24553773

  9. Production of Chondroitin Sulphate from Head, Skeleton and Fins of Scyliorhinus canicula By-Products by Combination of Enzymatic, Chemical Precipitation and Ultrafiltration Methodologies

    Science.gov (United States)

    Blanco, María; Fraguas, Javier; Sotelo, Carmen G.; Pérez-Martín, Ricardo I.; Vázquez, José Antonio

    2015-01-01

    This study illustrates the optimisation of the experimental conditions of three sequential steps for chondroitin sulphate (CS) recovery from three cartilaginous materials of Scyliorhinus canicula by-products. Optimum conditions of temperature and pH were first obtained for alcalase proteolysis of head cartilage (58 °C/pH 8.5/0.1% (v/w)/10 h of hydrolysis). Then, similar optimal conditions were observed for skeletons and fin materials. Enzymatic hydrolysates were subsequently treated with a combination of alkaline hydroalcoholic saline solutions in order to improve the protein hydrolysis and the selective precipitation of CS. Ranges of 0.53–0.64 M (NaOH) and 1.14–1.20 volumes (EtOH) were the levels for optimal chemical treatment depending on the cartilage origin. Finally, selective purification and concentration of CS and protein elimination of samples obtained from chemical treatment, was assessed by a combination of ultrafiltration and diafiltration (UF-DF) techniques at 30 kDa. PMID:26023837

  10. Production of Chondroitin Sulphate from Head, Skeleton and Fins of Scyliorhinus canicula By-Products by Combination of Enzymatic, Chemical Precipitation and Ultrafiltration Methodologies

    Directory of Open Access Journals (Sweden)

    María Blanco

    2015-05-01

    Full Text Available This study illustrates the optimisation of the experimental conditions of three sequential steps for chondroitin sulphate (CS recovery from three cartilaginous materials of Scyliorhinus canicula by-products. Optimum conditions of temperature and pH were first obtained for alcalase proteolysis of head cartilage (58 °C/pH 8.5/0.1% (v/w/10 h of hydrolysis. Then, similar optimal conditions were observed for skeletons and fin materials. Enzymatic hydrolysates were subsequently treated with a combination of alkaline hydroalcoholic saline solutions in order to improve the protein hydrolysis and the selective precipitation of CS. Ranges of 0.53–0.64 M (NaOH and 1.14–1.20 volumes (EtOH were the levels for optimal chemical treatment depending on the cartilage origin. Finally, selective purification and concentration of CS and protein elimination of samples obtained from chemical treatment, was assessed by a combination of ultrafiltration and diafiltration (UF-DF techniques at 30 kDa.

  11. Distribution of intratracheally administered plutonium-239 within the skeleton bones

    International Nuclear Information System (INIS)

    The data are presented on distribution of the intratracheally administered plutonium-239 within the skeleton bones. Plutonium was found to be distributed non-uniformly within the skeleton: it was concentrated mainly in the bones where the trabecular fraction of the bone tissue was most manifest. The results obtained were supported by the correlation analysis

  12. Isotopic age determinations in Bergslagen, Sweden. 3

    International Nuclear Information System (INIS)

    Rb-Sr whole-rock isotope analyses of five granite and two diorite samples of the Hyttsjoe Suite of intrusions in the Filipstad region, Central Sweden, yield an isochron age of 1841 +- 55 Ma with an initial 87Sr/86Sr ratio of 0.70217 +- 0.00098. This age is regarded as the emplacement age of the Hyttsjoe Suite of gabbros-diorites-tonalites-granites, which thus represents an intrusive subdivision of the 1.9-1.8 Ga Bergslagen Supracrustal Series. (Auth.)

  13. Versatility of Distraction Osteogenesis for the Craniofacial Skeleton.

    Science.gov (United States)

    Klement, Kristen A; Black, Jonathan S; Denny, Arlen D

    2016-05-01

    Malformations of the craniofacial skeleton are common. Restoration of anatomic shape, size, and position has been traditionally accomplished using autologous bone grafting to fill gaps created by surgery and segmental movement. The authors present their practice using distraction in many different ages and settings over 20 years. A retrospective review was performed of all craniofacial patients treated using distraction osteogenesis for mandible, midface, and calvarium. The authors identified 205 patient. Mandible: 112 patients were treated at an average age of 3.4 years. 18.8% of patients required repeat distraction. There was no difference in the neonatal versus older group (P = 0.71). There were significantly higher reoperation rates in syndromic children (P occlusal changes. Calvarium: 33 patients were treated at an average age of 4.7 years. No repeat distractions were performed. One patient required an additional advancement procedure. Distraction demonstrates successful long-term correction of defects in the craniofacial skeleton with the versatility and control needed to treat the wide spectrum of deformity. PMID:26999694

  14. Anatomy of the red cell membrane skeleton: unanswered questions.

    Science.gov (United States)

    Lux, Samuel E

    2016-01-14

    The red cell membrane skeleton is a pseudohexagonal meshwork of spectrin, actin, protein 4.1R, ankyrin, and actin-associated proteins that laminates the inner membrane surface and attaches to the overlying lipid bilayer via band 3-containing multiprotein complexes at the ankyrin- and actin-binding ends of spectrin. The membrane skeleton strengthens the lipid bilayer and endows the membrane with the durability and flexibility to survive in the circulation. In the 36 years since the first primitive model of the red cell skeleton was proposed, many additional proteins have been discovered, and their structures and interactions have been defined. However, almost nothing is known of the skeleton's physiology, and myriad questions about its structure remain, including questions concerning the structure of spectrin in situ, the way spectrin and other proteins bind to actin, how the membrane is assembled, the dynamics of the skeleton when the membrane is deformed or perturbed by parasites, the role lipids play, and variations in membrane structure in unique regions like lipid rafts. This knowledge is important because the red cell membrane skeleton is the model for spectrin-based membrane skeletons in all cells, and because defects in the red cell membrane skeleton underlie multiple hemolytic anemias. PMID:26537302

  15. Isotopic age determinations in Bergslagen, Sweden. 2

    International Nuclear Information System (INIS)

    This paper reports the isotopic dating of a Filipstad-type granite with rapakivi facies, exposed around the village of Rockesholm, about 20 km S of Grythyttan. Ten samples were taken from the river bed at Rockesholm dam site and two from nearby exposures. The Rb and Sr concentrations and Rb/Sr ratios of the whole-rocks were determined by X-ray fluorescence spectrometry. All samples were measured as pressed-powder pellets; the mass-absorption corrections for both sample and external standard are based upon the Compton scattering of the Mo-Kα primary beam. The biotite was analysed for Rb and Sr by mass-spectrometric isotope dilution. Sr isotopic compositions were determined directly on unspiked Sr for whole-rocks and calculated from the isotope dilution runs for the biotite. From the Rb-Sr whole-rock data it is concluded that the Filipstad-type granite at Rockesholm has been emplaced about 1700 Ma ago. (Auth.)

  16. Impact of asteroseismology on improving stellar ages determination

    CERN Document Server

    Lebreton, Yveline

    2013-01-01

    High precision photometry as performed by the CoRoT and Kepler satellites on-board instruments has allowed to detect stellar oscillations over the whole HR diagram. Oscillation frequencies are closely related to stellar interior properties via the density and sound speed profiles, themselves tightly linked with the mass and evolutionary state of stars. Seismic diagnostics performed on stellar internal structure models allow to infer the age and mass of oscillating stars. The accuracy and precision of the age determination depend both on the goodness of the observational parameters (seismic and classical) and on our ability to model a given star properly. They therefore suffer from any misunderstanding of the physical processes at work inside stars (as microscopic physics, transport processes...). In this paper, we recall some seismic diagnostics of stellar age and we illustrate their efficiency in age-dating the CoRoT target HD 52265.

  17. Differences in the initial deposition of Pu and Ra in the skeleton

    International Nuclear Information System (INIS)

    The ratio (still unknown) relating the experimentally determined effects of Pu and Ra in some animal species to observed effects of various isotopes of Ra in man presently provides the most reasonable basis for an assessment of the risk resulting to man from Pu. Extensive studies with the beagle have shown that an evaluation of this ratio on the basis of average skeletal radiation dose is complicated by several factors, one of which is the difference in the initial (gross) distribution of Pu and Ra between the various skeletal parts. Studies on the initial deposition of Pu and Ra in the whole skeleton and in individual parts of the skeleton after injection of the two nuclides as citrates demonstrated that significant differences in the distribution within the various skeletal parts exist, although the total deposition of the two nuclides in the whole skeleton is practically the same

  18. Adipose tissue, the skeleton and cardiovascular disease

    Energy Technology Data Exchange (ETDEWEB)

    Wiklund, Peder

    2011-07-01

    Cardiovascular disease (CVD) is the leading cause of death in the Western World, although the incidence of myocardial infarction (MI) has declined over the last decades. However, obesity, which is one of the most important risk factors for CVD, is increasingly common. Osteoporosis is also on the rise because of an aging population. Based on considerable overlap in the prevalence of CVD and osteoporosis, a shared etiology has been proposed. Furthermore, the possibility of interplay between the skeleton and adipose tissue has received increasing attention the last few years with the discovery that leptin can influence bone metabolism and that osteocalcin can influence adipose tissue. A main aim of this thesis was to investigate the effects of fat mass distribution and bone mineral density on the risk of MI. Using dual-energy x-ray absorptiometry (DEXA) we measured 592 men and women for regional fat mass in study I. In study II this was expanded to include 3258 men and women. In study III 6872 men and women had their bone mineral density measured in the total hip and femoral neck using DEXA. We found that a fat mass distribution with a higher proportion of abdominal fat mass was associated with both an adverse risk factor profile and an increased risk of MI. In contrast, a higher gynoid fat mass distribution was associated with a more favorable risk factor profile and a decreased risk of MI, highlighting the different properties of abdominal and gynoid fat depots (study I-II). In study III, we investigated the association of bone mineral density and risk factors shared between CVD and osteoporosis, and risk of MI. We found that lower bone mineral density was associated with hypertension, and also tended to be associated to other CVD risk factors. Low bone mineral density was associated with an increased risk of MI in both men and women, apparently independently of the risk factors studied (study III). In study IV, we investigated 50 healthy, young men to determine if

  19. Adipose tissue, the skeleton and cardiovascular disease

    International Nuclear Information System (INIS)

    Cardiovascular disease (CVD) is the leading cause of death in the Western World, although the incidence of myocardial infarction (MI) has declined over the last decades. However, obesity, which is one of the most important risk factors for CVD, is increasingly common. Osteoporosis is also on the rise because of an aging population. Based on considerable overlap in the prevalence of CVD and osteoporosis, a shared etiology has been proposed. Furthermore, the possibility of interplay between the skeleton and adipose tissue has received increasing attention the last few years with the discovery that leptin can influence bone metabolism and that osteocalcin can influence adipose tissue. A main aim of this thesis was to investigate the effects of fat mass distribution and bone mineral density on the risk of MI. Using dual-energy x-ray absorptiometry (DEXA) we measured 592 men and women for regional fat mass in study I. In study II this was expanded to include 3258 men and women. In study III 6872 men and women had their bone mineral density measured in the total hip and femoral neck using DEXA. We found that a fat mass distribution with a higher proportion of abdominal fat mass was associated with both an adverse risk factor profile and an increased risk of MI. In contrast, a higher gynoid fat mass distribution was associated with a more favorable risk factor profile and a decreased risk of MI, highlighting the different properties of abdominal and gynoid fat depots (study I-II). In study III, we investigated the association of bone mineral density and risk factors shared between CVD and osteoporosis, and risk of MI. We found that lower bone mineral density was associated with hypertension, and also tended to be associated to other CVD risk factors. Low bone mineral density was associated with an increased risk of MI in both men and women, apparently independently of the risk factors studied (study III). In study IV, we investigated 50 healthy, young men to determine if

  20. Deaths by ZIP Code by Age, 2013

    Data.gov (United States)

    U.S. Department of Health & Human Services — This dataset is for death of California residents, by Zip Code, by age group by place of residence. The death counts per age group, represents the deaths to...

  1. Low-Level Mechanical Vibrations can Reduce Bone Resorption and Enhance Bone Formation in the Growing Skeleton

    Energy Technology Data Exchange (ETDEWEB)

    Xie,L.; Jacobsen, J.; Busa, B.; Donahue, L.; Miller, L.; Rubin, C.; Judex, S.

    2006-01-01

    Short durations of extremely small magnitude, high-frequency, mechanical stimuli can promote anabolic activity in the adult skeleton. Here, it is determined if such signals can influence trabecular and cortical formative and resorptive activity in the growing skeleton, if the newly formed bone is of high quality, and if the insertion of rest periods during the loading phase would enhance the efficacy of the mechanical regimen. Eight-week-old female BALB/cByJ mice were divided into four groups, baseline control (n = 8), age-matched control (n = 10), whole-body vibration (WBV) at 45 Hz (0.3 g) for 15 min day{sup -1} (n = 10), and WBV that were interrupted every second by 10 of rest (WBV-R, n = 10). In vivo strain gaging of two additional mice indicated that the mechanical signal induced strain oscillations of approximately 10 microstrain on the periosteal surface of the proximal tibia. After 3 weeks of WBV, applied for 15 min each day, osteoclastic activity in the trabecular metaphysis and epiphysis of the tibia was 33% and 31% lower (P < 0.05) than in age-matched controls. Bone formation rates (BFR{center_dot}BS{sup -1}) on the endocortical surface of the metaphysis were 30% greater (P < 0.05) in WBV than in age-matched control mice but trabecular and middiaphyseal BFR were not significantly altered. The insertion of rest periods (WBV-R) failed to potentiate the cellular effects. Three weeks of either WBV or WBV-R did not negatively influence body mass, bone length, or chemical bone matrix properties of the tibia. These data indicate that in the growing skeleton, short daily periods of extremely small, high-frequency mechanical signals can inhibit trabecular bone resorption, site specifically attenuate the declining levels of bone formation, and maintain a high level of matrix quality. If WBV prove to be efficacious in the growing human skeleton, they may be able to provide the basis for a non-pharmacological and safe means to increase peak bone mass and, ultimately

  2. The Skeleton Forming Proteome of an Early Branching Metazoan: A Molecular Survey of the Biomineralization Components Employed by the Coralline Sponge Vaceletia Sp.

    Directory of Open Access Journals (Sweden)

    Juliane Germer

    Full Text Available The ability to construct a mineralized skeleton was a major innovation for the Metazoa during their evolution in the late Precambrian/early Cambrian. Porifera (sponges hold an informative position for efforts aimed at unraveling the origins of this ability because they are widely regarded to be the earliest branching metazoans, and are among the first multi-cellular animals to display the ability to biomineralize in the fossil record. Very few biomineralization associated proteins have been identified in sponges so far, with no transcriptome or proteome scale surveys yet available. In order to understand what genetic repertoire may have been present in the last common ancestor of the Metazoa (LCAM, and that may have contributed to the evolution of the ability to biocalcify, we have studied the skeletal proteome of the coralline demosponge Vaceletia sp. and compare this to other metazoan biomineralizing proteomes. We bring some spatial resolution to this analysis by dividing Vaceletia's aragonitic calcium carbonate skeleton into "head" and "stalk" regions. With our approach we were able to identify 40 proteins from both the head and stalk regions, with many of these sharing some similarity to previously identified gene products from other organisms. Among these proteins are known biomineralization compounds, such as carbonic anhydrase, spherulin, extracellular matrix proteins and very acidic proteins. This report provides the first proteome scale analysis of a calcified poriferan skeletal proteome, and its composition clearly demonstrates that the LCAM contributed several key enzymes and matrix proteins to its descendants that supported the metazoan ability to biocalcify. However, lineage specific evolution is also likely to have contributed significantly to the ability of disparate metazoan lineages to biocalcify.

  3. Absolute age determination of quaternary faults

    International Nuclear Information System (INIS)

    To constrain the age of neotectonic fault movement, Rb-Sr, K-Ar, U-series disequilibrium, C-14 and Be-10 methods were applied to the fault gouges, fracture infillings and sediments from the Malbang, Ipsil, Wonwonsa faults faults in the Ulsan fault zone, Yangsan fault in the Yeongdeog area and southeastern coastal area. Rb-Sr and K-Ar data imply that the fault movement of the Ulan fault zone initiated at around 30 Ma and preliminary dating result for the Yang san fault is around 70 Ma in the Yeongdeog area. K-Ar and U-series disequilibrium dating results for fracture infillings in the Ipsil fault are consistent with reported ESR ages. Radiocarbon ages of quaternary sediments from the Jeongjari area are discordant with stratigraphic sequence. Carbon isotope data indicate a difference of sedimentry environment for those samples. Be-10 dating results for the Suryum fault area are consistent with reported OSL results

  4. Absolute age determination of quaternary faults

    Energy Technology Data Exchange (ETDEWEB)

    Cheong, Chang Sik; Lee, Seok Hoon; Choi, Man Sik [Korea Basic Science Institute, Seoul (Korea, Republic of)] (and others)

    2000-03-15

    To constrain the age of neotectonic fault movement, Rb-Sr, K-Ar, U-series disequilibrium, C-14 and Be-10 methods were applied to the fault gouges, fracture infillings and sediments from the Malbang, Ipsil, Wonwonsa faults faults in the Ulsan fault zone, Yangsan fault in the Yeongdeog area and southeastern coastal area. Rb-Sr and K-Ar data imply that the fault movement of the Ulan fault zone initiated at around 30 Ma and preliminary dating result for the Yang san fault is around 70 Ma in the Yeongdeog area. K-Ar and U-series disequilibrium dating results for fracture infillings in the Ipsil fault are consistent with reported ESR ages. Radiocarbon ages of quaternary sediments from the Jeongjari area are discordant with stratigraphic sequence. Carbon isotope data indicate a difference of sedimentry environment for those samples. Be-10 dating results for the Suryum fault area are consistent with reported OSL results.

  5. Age as a Determinant of Interpersonal Evaluations.

    Science.gov (United States)

    Scheier, Michael F.; Schulz, Richard

    This study focuses on the impact of age on interpersonal evaluation of persons, particularly the elderly as individuals and not as a group. Using a 75-year-old target and a 23-year-old target, the experimenter predicted and found support for the idea that personal information contained in a transcript would evoke sympathy, and thereby lead…

  6. Determination of the efficacy of orally administered Ca-EDTA for the provocative chelation of Pb-210 from the skeleton of the baboon

    International Nuclear Information System (INIS)

    An oral chelation procedure was performed upon an adult female baboon to determine the efficacy of orally administered Ca-EDTA for use in diagnostic evaluation of skeletal burdens of Pb-210. Concentrations of Pb-210 in sequential urine samples from the baboon were determined as an indication of the removal of Pb-210 from the body. The results of the oral chelation with EDTA are compared to previous chelation procedures performed by IV infusion with EDTA and DTPA

  7. Evaluation by biphotonic absorbtiometry of the bony mineral content and determination of the fracture threshold in a population of patients between the ages of 60 and 75 years

    International Nuclear Information System (INIS)

    A measurement of the bony density of vertebrae and femur was carried out, in the course of a prospective study, in 99 patients between the ages of 60 and 75 years, living in northern France. 76 patients had no recognized problem of demineralization and 23 others were consulting for an evaluation of vertebral compression. The measurement of the bony density was done by biphotonic absorbtiometry with a source of labelled Gadolinium. In women, a significant difference in the values obtained by absorbtiometry in terms of the existence of vertebral compressions, symptomatic or not, is noted. A statistical study using the ROC curves method (Receiver Operating System) has enabled us to determine a threshold of high risk of vertebral fracture measured at 31 g or 0.85 g/cm2 in women, and 35 g or 0.85 g/cm2 in men. In addition, there is a significant correlation with the vertebral radiographical index as defined by Meunier. Among the various factors of influence which were studied, only the size and the morphotype seem to play an essential role in our study group. The comparative study of the densities measured in the femoral neck and the lumbar spine enabled us to find a very significant correlation in patients with as well as without compression (r = 0.714, p < 0.001). Biphotonic absorbtiometry proves therefore to be a method which may be used to define a group with a high fracture risk permitting to determine, as early as possible, therapeutic, curative and preventive measures

  8. Isotopic age determination in Bergslagen, Sweden. 1. Introduction

    Energy Technology Data Exchange (ETDEWEB)

    Oen, I.S. (Amsterdam Univ. (Netherlands). Geologisch Inst.); Verschure, R.H. (Laboratorium voor Isotopen-Geologie, Amsterdam (Netherlands))

    1982-09-01

    This paper is an introduction to a series of short communications 'Isotopic age determinations in Bergslagen, Sweden', which will be submitted to this journal. An earlier paper on K-Ar ages of hornblendes in skarns and metabasites in the Hjulsjoe area has been published elsewhere (Moorman et al., 1982). This joint research project of the ZWO-Laboratory of Isotope Geology and the Geological Institute University of Amsterdam forms part of the research program of the 'Stichting voor Isotopen-Geologisch Onderzoek', supported by the Netherlands Organization for the Advancement of Pure Research (Z.W.O.).

  9. The new age determination of Polar Ural eclogites

    International Nuclear Information System (INIS)

    By the method of Sm-Nd dating the age of minerals within eclogites of the Polar Urals was determined. Essential difference in mineral age of barruazite eclogite (366 ± 8.5 mln. years) and kyanite eclogite (339 ± 16 mln. years) was ascertained. Discrete stages of the eclogites formation can be among the reasons for the difference observed. It is pointed out that variations in Sm/Nd ratios of the eclogites can be related either to differentiation at magmatic stage or to metamorphism

  10. Determinants of differences in the activity budgets of Rhinopithecus bieti by age/sex class at Xiangguqing in the Baimaxueshan nature reserve, China

    Directory of Open Access Journals (Sweden)

    Li Yanhong

    2015-01-01

    Full Text Available Ecological factors are known to influence the activity budgets of Yunnan snub-nosed monkeys (Rhinopithecus bieti. However, little is known about how activity budgets vary between age/sex classes, because the species is difficult to observe in the wild. This study provides the first detailed activity budgets subdivided by age/sex classes based on observations of the largest habituated group at Xiangguqing in Baimaxueshan Nature Reserve. This study was conducted from June 2008 to May 2009. We found that adult females spent more time feeding (44.8% than adult males (39.5%, juveniles (39.1%, and infants (14.2%. Adult males allocated more time to miscellaneous activities (12.5% than did adult females (3.8%. Infants were being groomed 6.9% of the time, which was the highest proportion among all age/sex classes. Adults spent more time feeding, while immature individuals allocated more time to moving and other activities. There are several reasons activity budgets may vary by age/sex class: 1 differential reproductive investment between males and females; 2 developmental differences among the age categories; 3 social relationships between members of different age/sex classes, particularly dominance. In addition, group size and adult sex ratio may also impact activity budgets. These variations in activity budgets among the different age/sex classes may become a selective pressure that shapes the development and growth pattern in this species.

  11. Two age populations of zircons from the Timber Creek kimberlites, Northern Territory, as determined by laser-ablation ICP-MS analysis

    International Nuclear Information System (INIS)

    Two populations of kimberlitic zircon are present in the Timber Creek kimberlites, Northern Territory. Laser-ablation ICP-MS U-Pb dating yields an age of 1483 ± 15 (2σ) Ma for the main group and an age of 179 ± 2 Ma for the other group. This distinction of two age groups is strongly supported by Hf isotope data on the same zircons. Although the trace-element patterns of both populations are typical of mantle-derived zircons, the 'young' population has slightly higher concentrations of most trace elements, but has lower Hf, Nb, Ta and Pb contents. The distinct differences in trace-element contents and Hf isotopic composition of the two zircon populations indicate that they were derived from different magma sources. The dating results indicate that the emplacement age of the Timber Creek kimberlites cannot be older than the age of the 'young' zircon population (i.e. 179 ± 2 Ma). This clarifies the inconsistency between the previously reported SHRIMP age of the Timber Creek zircons (1462 ± 53 Ma) and the much younger age (1200Ma) of the sediments of the Victoria River Basin into which these kimberlites have intruded. The Timber Creek kimberlites are a newly recognised extension of the widespread Jurassic kimberlite activity known in Western Australia and South Australia. Copyright (2001) Geological Society of Australia

  12. Age- and gender-specific differences in left and right ventricular cardiac function and mass determined by cine magnetic resonance imaging

    International Nuclear Information System (INIS)

    We examined possible age- and gender-specific differences in the function and mass of left (LV) and right (RV) ventricles in 36 healthy volunteers using cine gradient-recalled echo magnetic resonance imaging. Subjects were divided into four groups (nine men and nine women in each): men aged under 45 years (32 ± 7), women aged under 45 (27 ± 6), men aged over 45 (59 ± 8), and women aged over 45 (57 ± 9). Functional analysis of cardiac volume and mass and of LV wall motion was performed by manual segmentation of the endocardial and epicardial borders of the end-diastolic and end-systolic frame; both absolute and normalized (per square meter body surface area) values were evaluated. With age there was a significant decrease in both absolute and normalized LV and RV chamber volumes (EDV, ESV), while LV and RV masses remained unchanged. Gender-specific differences were found in cardiac mass and volume (for men and women, respectively: LV mass, 155 ± 18 and 110 ± 16 g; LV EDV, 118 ± 27 and 96 ± 21 ml; LV ESV, 40 ± 13 and 29 ± 9 ml; RV mass, 52 ± 10 and 39 ± 5 g; RV EDV, 131 ± 28 and 100 ± 23 ml; RV ESV, 53 ± 17 and 33 ± 15 ml). Normalization to body surface area eliminated differences in LV volumes but not those in LV mass, RV mass, or RV function. Functional parameters such as cardiac output and LV ejection fraction showed nonsignificant or only slight differences and were thus largely independent of age and gender. Intra- and interobserver variability ranged between 1.4 % and 5.9 % for all parameters. Cine magnetic resonance imaging thus shows age- and gender-specific differences in cardiac function, and therefore the evaluation of cardiac function in patients should consider age- and gender-matched normative values. (orig.)

  13. Pteridine fluorescence for age determination of Anopheles mosquitoes.

    Science.gov (United States)

    Wu, D; Lehane, M J

    1999-02-01

    The age structure of mosquito populations is of great relevance to understanding the dynamics of disease transmission and in monitoring the success of control operations. Unfortunately, the ovarian dissection methods currently available for determining the age of adult mosquitoes are technically difficult, slow and may be of limited value, because the proportion of diagnostic ovarioles in the ovary declines with age. By means of reversed-phase HPLC this study investigated the malaria vectors Anopheles gambiae and An. stephensi to see if changes in fluorescent pteridine pigments, which have been used in other insects to determine the age of field-caught individuals, may be useful for age determination in mosquitoes. Whole body fluorescence was inversely proportional to age (P 91%) up to 30 days postemergence, with the regression values: y = 40580-706x for An. gambiae, and y = 52896-681x for An. stephensi. In both species the main pteridines were 6-biopterin, pterin-6-carboxylic acid and an unidentified fluorescent compound. An. gambiae had only 50-70% as much fluorescence as An. stephensi, and fluorescent compounds were relatively more concentrated in the head than in the thorax (ratios 1:0.8 An. gambiae; 1:0.5 An. stephensi). The results of this laboratory study are encouraging. It seems feasible that this simpler and faster technique of fluorescence quantification could yield results of equivalent accuracy to the interpretation of ovarian dissection. A double-blind field trial comparing the accuracy of this technique to marked, released and recaptured mosquitoes is required to test the usefulness of the pteridine method in the field. PMID:10194749

  14. Bomb dating, age validation and quality control of age determinations of monodontids and other marine mammals

    Directory of Open Access Journals (Sweden)

    Steven E Campana

    2014-05-01

    Full Text Available Methods for confirming the accuracy of age determination methods are reasonably well established in fishes, but the millions of routine age determinations which take place every year require their own quality control protocols. In contrast, methods for ensuring accuracy in age determination of monodontids and other marine mammals are still being developed. Here we review the basis and application of bomb radiocarbon to marine mammal age validation, highlighting its value for providing unambiguous estimates of age for belugas and other long-lived animals which form growth bands. Bomb radiocarbon is particularly useful for marine mammals, given that the age of an individual animal can be determined to within ±1-3 years, as long as it was alive during the 1960s. However, ongoing age determinations require careful monitoring to ensure that age interpretations remain consistent across ages and through time. Quality control protocols using reference collections of ageing material, in conjunction with age bias plots and measures of precision, are capable of detecting virtually all of the systematic ageing errors that often occur once age determinations of an animal become routine.

  15. DNA Damage: A Main Determinant of Vascular Aging.

    Science.gov (United States)

    Bautista-Niño, Paula K; Portilla-Fernandez, Eliana; Vaughan, Douglas E; Danser, A H Jan; Roks, Anton J M

    2016-01-01

    Vascular aging plays a central role in health problems and mortality in older people. Apart from the impact of several classical cardiovascular risk factors on the vasculature, chronological aging remains the single most important determinant of cardiovascular problems. The causative mechanisms by which chronological aging mediates its impact, independently from classical risk factors, remain to be elucidated. In recent years evidence has accumulated that unrepaired DNA damage may play an important role. Observations in animal models and in humans indicate that under conditions during which DNA damage accumulates in an accelerated rate, functional decline of the vasculature takes place in a similar but more rapid or more exaggerated way than occurs in the absence of such conditions. Also epidemiological studies suggest a relationship between DNA maintenance and age-related cardiovascular disease. Accordingly, mouse models of defective DNA repair are means to study the mechanisms involved in biological aging of the vasculature. We here review the evidence of the role of DNA damage in vascular aging, and present mechanisms by which genomic instability interferes with regulation of the vascular tone. In addition, we present potential remedies against vascular aging induced by genomic instability. Central to this review is the role of diverse types of DNA damage (telomeric, non-telomeric and mitochondrial), of cellular changes (apoptosis, senescence, autophagy), mediators of senescence and cell growth (plasminogen activator inhibitor-1 (PAI-1), cyclin-dependent kinase inhibitors, senescence-associated secretory phenotype (SASP)/senescence-messaging secretome (SMS), insulin and insulin-like growth factor 1 (IGF-1) signaling), the adenosine monophosphate-activated protein kinase (AMPK)-mammalian target of rapamycin (mTOR)-nuclear factor kappa B (NFκB) axis, reactive oxygen species (ROS) vs. endothelial nitric oxide synthase (eNOS)-cyclic guanosine monophosphate (c

  16. K/C age determination in potassium fieldspars

    International Nuclear Information System (INIS)

    A method for the potassium/calcium age determination of geological material is described. The calcium isotope intensities are measured with a mass spectrometer by the thermal ionization technique. The 42Ca/44Ca isotope ratio is used as an internal standard to correct the measured 40Ca/42Ca ratio for mass discrimination. The radiogenic 40Ca portion and the calcium content of the minerals are determined in different analytical steps. Two feldspars are dated with relative standard deviations of 1.8 and 4 per cent, respectively. (orig.)

  17. The deglaciation of Iztaccíhuatl volcano (Mexico) from the Little Ice Age maximum to the present, determined by photogrametry and lichenometry

    Science.gov (United States)

    Palacios, D.; García-Sancho, L.; Zamorano, J. J.; Andrés, N.; Pintado, A.

    2012-04-01

    Iztaccíhualt Volcano (19°10'20''N, 98°38'30''W, 5230 m asl) preserves an important moraine complex from the Little Ice Age (LIA), which stretches to 4300 m asl. These moraines are different from former ones because they are not covered by ash fall from the last plinian explosive phases of the nearby Popocatépetl volcano. In fact, the last emission of those pyroclasts took place during the XI century (Vázquez-Selem, 2000). The summit area of the Iztaccíhualt volcano still has glaciers whose terminus are located around 5000 m asl. From the end of the LIA until present the glacier terminus have ascended 700 m. To study the deglaciation process in Iztaccíhualt volcano from the LIA maximum to present, the Ayoloco valley was selected as it is the most important valley of the western slope of the volcano. Taking this valley as a reference, we determined the limits of glaciers in different dates by georeferencing the aerial and panoramic photographs (from 1897 to 2000) and analysing the 1958 field cartography of the glacial limits (Lorenzo, 1964). On the one hand, we carried out a statistical analysis of the size of the Rhizocarpon geographicum thallus and, on the other hand, we undertook a statistical study of the biodiversity of the lichen species through a number of cross-sections from the lowest LIA moraines to the current glacier snouts. This methodology allowed dating the exact moment in which the glacier retreated over certain points of the analysed cross-sections and determining the ecesis and the growth curve of the Rhizocarpon geographicum specie. In the Ayoloco valley the average growth rate is of 0.23 mm per year. From this information, we could deduce the evolution of the glacier from the LIA maximum to present. The results indicate that two main advances took place during the XVII and the XIX centuries. At the beginning of the XX century the glacier terminus were very close to the moraines of the maximum advance. An intense glacial retreat took place

  18. The Success Rate in a Complicated Spatial Memory Test Is Determined by Age, Sex, Life History and Search Strategies in Cynomolgus Monkeys

    DEFF Research Database (Denmark)

    Darusman, Huda S; Kalliokoski, Otto; Sajuthi, Dondin;

    2014-01-01

    to failure and chronological memory recall. These strategies appeared to be shared by most subjects, however, the overall success rate appeared to also depend on individual characteristics including age, gender and whether the subject had been born in caged captivity or not. By elucidating some of...

  19. A Robust Rigid Skeleton Extraction Method from Noisy Visual Hull Model

    Directory of Open Access Journals (Sweden)

    Xiaojun Wu

    2015-04-01

    Full Text Available The existing skeleton extraction algorithms from a coarse and noisy model cannot achieve a satisfactory skeleton, let alone the joints’ central position in a markerless motion capture system (e.g., a rigid skeleton. To solve this problem, we propose a rigid skeleton extraction algorithm from a noisy visual hull model with phantom volumes. Firstly, we reconstruct the subject visual hull and the corresponding volumetric model from a multiple-view synchronized video sequence. Secondly, the curve skeleton of the volume model is computed based on the theory of repulsive force fields. Thirdly, we propose a criterion for linking a curved skeleton to link the different skeleton limbs using a back-tracking method. At the same time, we obtain the distance and angle threshold values adaptively using a binary search algorithm. Finally, after achieving a smooth curve skeleton, we determine the joints’ central positions in the skeleton using a priori information of the human body to form a rigid skeleton. Experimental results show that the proposed algorithm can obtain a desirable rigid skeleton with good robustness, less sensitivity to noise, and using an automatic procedure.

  20. The Derivation of Skeleton Lines for Terrain Features

    Institute of Scientific and Technical Information of China (English)

    2002-01-01

    The geometric and physical analysis methods are conventional methods for the derivation of skeleton lines in the fields of cartography,digital photogrammetry,and related areas.This paper proposes a stepwise approach that uses the physical analysis method in the first stage and the geometric analysis method in the subsequent stage.The physical analysis method analyses the terrain globally to obtain a rough set of skeleton lines for a terrain surface.The rough skeleton lines help to structure the ordering of feature points by the geometric analysis method.

  1. Determining the Type, Redshift, and Age of a Supernova Spectrum

    CERN Document Server

    Blondin, Stéphane

    2007-01-01

    We present an algorithm to identify the type of an SN spectrum and to determine its redshift and age. This algorithm, based on the correlation techniques of Tonry & Davis, is implemented in the Supernova Identification (SNID) code. It is used by members of ongoing high-redshift SN searches to distinguish between type Ia and type Ib/c SNe, and to identify "peculiar" SNe Ia. We develop a diagnostic to quantify the quality of a correlation between the input and template spectra, which enables a formal evaluation of the associated redshift error. Furthermore, by comparing the correlation redshifts obtained using SNID with those determined from narrow lines in the SN host galaxy spectrum, we show that accurate redshifts (with a typical error less than 0.01) can be determined for SNe Ia without a spectrum of the host galaxy. Last, the age of an input spectrum is determined with a typical 3-day accuracy, shown here by using high-redshift SNe Ia with well-sampled light curves. The success of the correlation techn...

  2. Radioactive labelling of alkaloids with morphine skeleton

    International Nuclear Information System (INIS)

    Results achieved by the sup(14)C, sup(125)I and sup(3)H labelling of alkaloids with morphine skeleton for kinetic, receptor, metabolims and pharmacological investigations are summarized and evaluated. The methods for the preparation of sup(3)H labelled dihydromorphine, dihydroethylmorphine, dihydrocodeine, naloxone and naloxazone are described. The compounds have higher specific molar activity than those referred to in literature which makes them suitable for a number of investigations. (author)

  3. Age assessment of ivory by analysis of 14C and 90Sr to determine whether there is an antique on hand.

    Science.gov (United States)

    Schmied, Stefanie A K; Brunnermeier, Matthias J; Schupfner, Robert; Wolfbeis, Otto S

    2011-04-15

    A method is described to determine whether an elephant has died before 1955 or not. This is accomplished by determination of the radionuclides (14)C and (90)Sr in artifacts made of ivory. The reliability of this method is considerably increased by double nuclide analysis and therefore is applicable for judicial expert opinions. PMID:21371831

  4. Platelet size and age determine platelet function independently

    International Nuclear Information System (INIS)

    A study was undertaken to examine the interaction of platelet size and age in determining in vitro platelet function. Baboon megakaryocytes were labeled in vivo by the injection of 75Se-methionine. Blood was collected when the label was predominantly associated with younger platelets (day 2) and with older platelets (day 9). Size-dependent platelet subpopulations were prepared on both days by counterflow centrifugation. The reactivity of each platelet subpopulation was determined on both days by measuring thrombin-induced aggregation. Platelets were fixed after partial aggregation had occurred by the addition of EDTA/formalin. After removal of the aggregated platelets by differential centrifugation, the supernatant medium was assayed for remaining platelets and 75Se radioactivity. Comparing day 2 and day 9, no significant difference was seen in the rate of aggregation of a given subpopulation. However, aggregation was more rapid in the larger platelet fractions than in the smaller ones on both days. A greater percentage of the 75Se radioactivity appeared in the platelet aggregates on day 2 than on day 9. This effect was independent of platelet size, as it occurred to a similar extent in the unfractionated platelets and in each of the size-dependent platelet subpopulations. The data indicate that young platelets are more active than older platelets. This study demonstrates that size and age are both determinants of platelet function, but by independent mechanisms

  5. Disconnected Skeleton: Shape at its Absolute Scale

    CERN Document Server

    Aslan, C; Erdem, E; Tari, S

    2011-01-01

    We present a new skeletal representation along with a matching framework to address the deformable shape recognition problem. The disconnectedness arises as a result of excessive regularization that we use to describe a shape at an attainably coarse scale. Our motivation is to rely on the stable properties of the shape instead of inaccurately measured secondary details. The new representation does not suffer from the common instability problems of traditional connected skeletons, and the matching process gives quite successful results on a diverse database of 2D shapes. An important difference of our approach from the conventional use of the skeleton is that we replace the local coordinate frame with a global Euclidean frame supported by additional mechanisms to handle articulations and local boundary deformations. As a result, we can produce descriptions that are sensitive to any combination of changes in scale, position, orientation and articulation, as well as invariant ones.

  6. Determination of Diastolic Dysfunction Cut-Off Value by Tissue Doppler Imaging in Adults 70 Years of Age or Older: A Comparative Analysis of Pulsed-Wave and Color-Coded Tissue Doppler Imaging

    OpenAIRE

    Baek, Hee-Kyung; Park, Tae-Ho; Park, Sun-Yi; Kim, Jung-Hwan; Seo, Jeong-Min; Kim, Woo-Jae; Nam, Young-Hee; Kim, Moo-Hyun; Kim, Young-Dae

    2011-01-01

    Background and Objectives The cut-off value of diastolic dysfunction by tissue Doppler imaging (TDI) is affected by aging and modalities used (pulsed-wave vs. color-coded). The purpose of this study was to investigate the diastolic function of healthy elderly people and to determine the appropriate cut-off value of diastolic dysfunction in elderly individuals. Subjects and Methods Healthy volunteers (n=76) and patients with hypertension (n=51) aged ≥70 years underwent 2-dimensional and Dopple...

  7. A novel strain energy relationship for red blood cell membrane skeleton based on spectrin stiffness and its application to micropipette deformation.

    Science.gov (United States)

    Svetina, Saša; Kokot, Gašper; Kebe, Tjaša Švelc; Žekš, Boštjan; Waugh, Richard E

    2016-06-01

    Red blood cell (RBC) membrane skeleton is a closed two-dimensional elastic network of spectrin tetramers with nodes formed by short actin filaments. Its three-dimensional shape conforms to the shape of the bilayer, to which it is connected through vertical linkages to integral membrane proteins. Numerous methods have been devised over the years to predict the response of the RBC membrane to applied forces and determine the corresponding increase in the skeleton elastic energy arising either directly from continuum descriptions of its deformation, or seeking to relate the macroscopic behavior of the membrane to its molecular constituents. In the current work, we present a novel continuum formulation rooted in the molecular structure of the membrane and apply it to analyze model deformations similar to those that occur during aspiration of RBCs into micropipettes. The microscopic elastic properties of the skeleton are derived by treating spectrin tetramers as simple linear springs. For a given local deformation of the skeleton, we determine the average bond energy and define the corresponding strain energy function and stress-strain relationships. The lateral redistribution of the skeleton is determined variationally to correspond to the minimum of its total energy. The predicted dependence of the length of the aspirated tongue on the aspiration pressure is shown to describe the experimentally observed system behavior in a quantitative manner by taking into account in addition to the skeleton energy an energy of attraction between RBC membrane and the micropipette surface. PMID:26376642

  8. Clinical and prognostic significance of bone marrow abnormalities in the appendicular skeleton detected by low-dose whole-body multidetector computed tomography in patients with multiple myeloma

    International Nuclear Information System (INIS)

    Clinical significance of medullary abnormalities in the appendicular skeleton (AS) detected by low-dose whole-body multidetector computed tomography (MDCT) in patients with multiple myeloma (MM) was investigated. A total of 172 patients with monoclonal gammopathy of undetermined significance (MGUS) (n=17), smoldering MM (n=47) and symptomatic MM (n=108) underwent low-dose MDCT. CT values (CTv) of medullary density of AS⩾0 Hounsfield unit (HU) was considered as abnormal. Percentage of medullary abnormalities and the mean CTv of AS in patients with MGUS, smoldering MM and symptomatic MM were 18, 55 and 62% and −44.5 , −20.3 and 11.2 HU, respectively (P<0.001 and P<0.001). Disease progression of MM was independently associated with high CTv on multivariate analysis. In symptomatic MM, the presence of abnormal medullary lesions was associated with increased incidence of high-risk cytogenetic abnormalities (34.4% vs 7.7% P=0.002) and extramedullary disease (10.4% vs 0% P=0.032). It was also an independent poor prognostic predictor (hazard ratio 3.546, P=0.04). This study showed that CTv of AS by MDCT is correlated with disease progression of MM, and the presence of abnormal medullary lesions is a predictor for poor survival

  9. The Difficulty of Sexing Skeletons from Unknown Populations

    Directory of Open Access Journals (Sweden)

    Ingrid Sierp

    2015-01-01

    Full Text Available Determination of sex from skeletal remains is performed using a number of methods developed by biological anthropology. They must be evaluated for consistency and for their performance in a forensic setting. Twenty skeletons of varied provenance had their sex determined by 15 existing methods of forensic anthropology (7 metric and 8 morphological. The methods were evaluated for their consistency in determination of sex. No single individual was identified as belonging to one sex exclusively. Ambiguous results were obtained by metric methods for fourteen individuals (70% and by morphological methods for only five individuals (25% (Chi-squared = 4.3, df = 1, P<0.05. Methods which use the size of bones as an indicator of sex perform poorly on skeletal remains of individuals of unknown provenance. Methods which combine morphologic and metric techniques, that is, geometric morphometric analysis, may result in greater levels of consistency.

  10. Parallel FFT using Eden Skeletons

    DEFF Research Database (Denmark)

    Berthold, Jost; Dieterle, Mischa; Lobachev, Oleg;

    2009-01-01

    approaches like calculating FFT using a parallel map-and-transpose skeleton provide more flexibility to overcome these problems. Assuming a distributed access to input data and re-organising computation to return results in a distributed way improves the parallel runtime behaviour....

  11. 77 FR 4858 - Culturally Significant Objects Imported for Exhibition Determinations: “Byzantium and Islam: Age...

    Science.gov (United States)

    2012-01-31

    ... Culturally Significant Objects Imported for Exhibition Determinations: ``Byzantium and Islam: Age of... determinations made by ] the Department of State pertaining to the exhibition ``Byzantium and Islam: Age of... Islam: Age of Transition (7th-9th Century),'' imported from abroad for temporary exhibition within...

  12. Phase transition of triangulated spherical surfaces with elastic skeletons

    OpenAIRE

    Koibuchi, Hiroshi

    2006-01-01

    A first-order transition is numerically found in a spherical surface model with skeletons, which are linked to each other at junctions. The shape of the triangulated surfaces is maintained by skeletons, which have a one-dimensional bending elasticity characterized by the bending rigidity $b$, and the surfaces have no two-dimensional bending elasticity except at the junctions. The surfaces swell and become spherical at large $b$ and collapse and crumple at small $b$. These two phases are separ...

  13. Plants flex their skeletons

    DEFF Research Database (Denmark)

    Foster, Randy; Mattsson, Ole; Mundy, John

    2003-01-01

    Recent work on the fragile fiber mutants of Arabidopsis has identified microtubule-associated proteins that affect the orientation of cellulose microfibrils in cell walls, a major determinant of plant elongation growth. These same proteins are implicated in responses to gibberellin, provoking fresh...

  14. Naked Stony Corals: Skeleton Loss in Scleractinia

    Energy Technology Data Exchange (ETDEWEB)

    Medina, Monica; Collins, Allen G.; Takaoka, Tori L.; Kuehl,Jennifer; Boore, Jeffrey L.

    2005-12-01

    Hexacorallia includes the Scleractinia, or stony corals, characterized by having an external calcareous skeleton made of aragonite, and the Corallimorpharia, or mushroom corals, that lack such a skeleton. Although each group has traditionally been considered monophyletic, some molecular phylogenetic analyses have challenged this, suggesting that skeletal features are evolutionarily plastic, and reviving notions that the scleractinian skeleton may be ephemeral and that the group itself may be polyphyletic. Nevertheless, the most comprehensive phylogenetic study of Hexacorallia supported scleractinian monophyly (REF), and so this remains controversial. In order to resolve this contentious issue, we sequenced the complete mitochondrial genome sequences of nine scleractinians and four corallimorpharians and performed phylogenetic analysis that also included three outgroups (an octocoral and two sea anemones). Our data provide the first strong evidence that Scleractinia is paraphyletic and that the Corallimorpharia is derived from within the group, from which we conclude that skeletal loss has occurred in the latter group secondarily. It is possible that a driving force in such skeletal loss could be the high levels of CO{sub 2} in the ocean during the mid-Cretaceous, which would have impacted aragonite solubility. We estimate from molecular divergence measures that the Corallimorpharia arose in the mid-Cretaceous, approximately 87 million years ago (Ma), supporting this view. These data also permit us to date the origin of Scleractinia to 265 Ma, narrowing the gap between the group's phylogenetic origin and its earliest fossil record.

  15. 3D Elastic Registration of Ultrasound Images Based on Skeleton Feature

    Institute of Scientific and Technical Information of China (English)

    LI Dan-dan; LIU Zhi-Yan; SHEN Yi

    2005-01-01

    In order to eliminate displacement and elastic deformation between images of adjacent frames in course of 3D ultrasonic image reconstruction, elastic registration based on skeleton feature was adopt in this paper. A new automatically skeleton tracking extract algorithm is presented, which can extract connected skeleton to express figure feature. Feature points of connected skeleton are extracted automatically by accounting topical curvature extreme points several times. Initial registration is processed according to barycenter of skeleton. Whereafter, elastic registration based on radial basis function are processed according to feature points of skeleton. Result of example demonstrate that according to traditional rigid registration, elastic registration based on skeleton feature retain natural difference in shape for organ's different part, and eliminate slight elastic deformation between frames caused by image obtained process simultaneously. This algorithm has a high practical value for image registration in course of 3D ultrasound image reconstruction.

  16. The age of second language acquisition determines the variability in activation elicited by narration in three languages in Broca's and Wernicke's area.

    Science.gov (United States)

    Bloch, Constantine; Kaiser, Anelis; Kuenzli, Esther; Zappatore, Daniela; Haller, Sven; Franceschini, Rita; Luedi, Georges; Radue, Ernst-Wilhelm; Nitsch, Cordula

    2009-02-01

    It is generally accepted that the presence of a second language (L2) has an impact on the neuronal substrates build up and used for language processing; the influence of the age of L2 exposure, however, is not established. We tested the hypothesis that the age of L2 acquisition has an effect on the cortical representation of a multilingual repertoire in 44 multilinguals with different age of exposure to a L2 (simultaneous or covert simultaneous exposure to L1 and L2, sequential acquisition of L1 and L2 between 1 and 5 years, late learning of L2 after 9 years of age) and all fluent in a late learned L3. Regional activation in a language production task showed a high in-between-subject variability, which was higher than within-subject variability between L1, L2, and L3. We, therefore, performed a single subject analysis and calculated the within-subject variance in the numbers of activated voxels in Broca's and Wernicke's area. Subjects with early exposure to L2 showed low variability in brain activation in all three languages, in the two early as well as the late learned language. In contrast, late multilinguals exhibited higher variability. Thus, cerebral representation of languages is linked to the age of L2 acquisition: early exposure to more than one language gives rise to a language processing network that is activated homogeneously by early and late learned languages, while the inhomogeneous activation in late multilinguals indicates more independent access to the multilingual repertoire. Early passive exposure to L2 results in the same low variance as active bilingual upbringing. Variability in local brain activity increases progressively from the simultaneous to late L2 exposure, indicating a gradual transition from the mode of early bilingual language representation to that of late ones. PMID:19061905

  17. DNA and bone structure preservation in medieval human skeletons

    OpenAIRE

    Coulson-Thomas, Yvette M.; Norton, Andrew L.; Coulson-Thomas, Vivien J.; Florencio-Silva, Rinaldo; Ali, Nadir; Elmrghni, Samir; Gil, Cristiane D; Sasso, Gisela R. S.; Ronald A. Dixon; Nader, Helena B.

    2015-01-01

    Morphological and ultrastructural data from archaeological human bones are scarce, particularly data that have been correlated with information on the preservation of molecules such as DNA. Here we examine the bone structure of macroscopically well-preserved medieval human skeletons by transmission electron microscopy and immunohistochemistry, and the quantity and quality of DNA extracted from these skeletons. DNA technology has been increasingly used for analyzing physical evidence in archae...

  18. Age determination of bottom sediments from Lake Hovsgol, Mongolia

    International Nuclear Information System (INIS)

    Dating plays a key role in determining past environmental changes in lake sediments cores. The feldspar post-IR infrared stimulated luminescence (IRSL) procedure is one of the IRSL procedures and has a great potential to date older samples compared to quartz optically stimulated luminescence (OSL). In this study, the post-IR IRSL (pIRIR) procedure was applied to the polymineral fine grained sediments from Lake Khuvsgul (Hovsgol), Mongolia, and these ages were compared to 14C ages of bulk samples from the certain depths. The pIRIR ages are always younger than 14C ages from bulk samples, however, it was possible to construct the suitable age model based on luminescence and 14C ages. Therefore, pIRIR225 protocol can be contributed to estimate the sedimentation age of lake sediments as well as 14C dating. (author)

  19. Tables for determining lead, uranium, and thorium isotope ages

    Science.gov (United States)

    Schonfeld, E.

    1974-01-01

    Tables for determining lead, uranium, and thorium isotope ages are presented in the form of computer printouts. Decay constants, analytical expressions for the functions evaluated, and the precision of the calculations are briefly discussed.

  20. Dioxasampsones A and B, two polycyclic polyprenylated acylphloroglucinols with unusual epoxy-ring-fused skeleton from Hypericum sampsonii.

    Science.gov (United States)

    Tian, Wen-Jing; Qiu, Yu-Qin; Yao, Xiao-Jun; Chen, Hai-Feng; Dai, Yi; Zhang, Xiao-Kun; Yao, Xin-Sheng

    2014-12-19

    Dioxasampsones A and B (1 and 2), two new polycyclic polyprenylated acylphloroglucinols with an unusual epoxy-ring-fused skeleton by new ways of cyclization, along with a new nor-PPAPs hypersampson R (3) with the loss of C-31-33 in isopentenyl, were isolated from the aerial parts of Hypericum sampsonii. 1 possessed an unexpected hexacyclic skeleton with a rare 2,7-dioxabicyclo[2.2.1]heptane moiety, and 2 featured a unique tetrahydrofuro[3,4-b]furan-fused tricycle[4.3.1.1(5,7)]undecane skeleton. The gross structures of the new compounds were determined by extensive NMR spectroscopic methods. Their absolute configurations were deduced by single-crystal X-ray diffraction and ECD calculations. PMID:25470320

  1. Deconstructing the Iboga Alkaloid Skeleton: Potentiation of FGF2-induced Glial Cell Line-Derived Neurotrophic Factor Release by a Novel Compound.

    Science.gov (United States)

    Gassaway, Madalee M; Jacques, Teresa L; Kruegel, Andrew C; Karpowicz, Richard J; Li, Xiaoguang; Li, Shu; Myer, Yves; Sames, Dalibor

    2016-01-15

    Modulation of growth factor signaling pathways in the brain represents a new experimental approach to treating neuropsychiatric disorders such as depression, anxiety, and addiction. Neurotrophins and growth factors exert synaptic, neuronal, and circuit level effects on a wide temporal range, which suggests a possibility of rapid and lasting therapeutic effects. Consequently, identification of small molecules that can either enhance the release of growth factors or potentiate their respective pathways will provide a drug-like alternative to direct neurotrophin administration or viral gene delivery and thus represents an important frontier in chemical biology and drug design. Glial cell line-derived neurotrophic factor (GDNF), in particular, has been implicated in marked reduction of alcohol consumption in rodent addiction models, and the natural product ibogaine, a substance used traditionally in ritualistic ceremonies, has been suggested to increase the synthesis and release of GDNF in the dopaminergic system in rats. In this report, we describe a novel iboga analog, XL-008, created by unraveling the medium size ring of the ibogamine skeleton, and its ability to induce release of GDNF in C6 glioma cells. Additionally, XL-008 potentiates the release of GDNF induced by fibroblast growth factor 2 (FGF2), another neurotrophin implicated in major depressive disorder, increasing potency more than 2-fold (from 7.85 ± 2.59 ng/mL to 3.31 ± 0.98 ng/mL) and efficacy more than 3-fold. The GDNF release by both XL-008 and the FGF2/XL-008 mixture was found to be mediated through the MEK and PI3K signaling pathways but not through PLCγ in C6 glioma cells. PMID:26517751

  2. X-ray - skeleton

    Science.gov (United States)

    A skeletal x-ray is an imaging test used to look at the bones. It is used to detect fractures , tumors, or ... in the health care provider's office by an x-ray technologist. You will lie on a table or ...

  3. Evidence of authentic DNA from Danish Viking Age skeletons untouched by humans for 1,000 years

    DEFF Research Database (Denmark)

    Melchior, Linea; Kivisild, Toomas; Lynnerup, Niels;

    2008-01-01

    drawn from present day European populations. Several of the haplotypes are either infrequent or have not been observed in modern Scandinavians. The observation of haplogroup I in the present study (<2% in modern Scandinavians) supports our previous findings of a pronounced frequency of this haplogroup...

  4. METHODS FOR AGE AND GROWTH DETERMINATION IN CEPHALOPODS

    OpenAIRE

    Svjetlana Krstulović Šifner

    2008-01-01

    Different methods used in age determination of cephalopods and their importance for assessment and management purposes for this group of marine organisms are described in the paper. Scientific investigations have proved that indirect methods (length frequency data) are not reliable enough and should always be accompanied with one direct method, although these methods are very demanding and time consuming. Today, statoliths are the most frequently used direct method for age estimation. These h...

  5. Non-financial determinants of the retirement age

    OpenAIRE

    Vermeer, C.A.F.

    2015-01-01

    This dissertation examines the importance of non-financial determinants for the individual retirement age. Recent increases in statutory retirement ages around the world point to the relevance of this issue. Financial incentives alone cannot fully explain observed retirement behavior. Chapter 2 examines the possible relevance of insights from behavioral economics and social norms for retirement and concludes that defaults, reference points and social norms are likely explanations for observed...

  6. Premating isolation is determined by larval rearing substrates in cactophilic Drosophila mojavensis. X. Age-specific dynamics of adult epicuticular hydrocarbon expression in response to different host plants.

    Science.gov (United States)

    Etges, William J; de Oliveira, Cassia C

    2014-06-01

    Analysis of sexual selection and sexual isolation in Drosophila mojavensis and its relatives has revealed a pervasive role of rearing substrates on adult courtship behavior when flies were reared on fermenting cactus in preadult stages. Here, we assessed expression of contact pheromones comprised of epicuticular hydrocarbons (CHCs) from eclosion to 28 days of age in adults from two populations reared on fermenting tissues of two host cacti over the entire life cycle. Flies were never exposed to laboratory food and showed significant reductions in average CHC amounts consistent with CHCs of wild-caught flies. Overall, total hydrocarbon amounts increased from eclosion to 14-18 days, well past age at sexual maturity, and then declined in older flies. Most flies did not survive past 4 weeks. Baja California and mainland populations showed significantly different age-specific CHC profiles where Baja adults showed far less age-specific changes in CHC expression. Adults from populations reared on the host cactus typically used in nature expressed more CHCs than on the alternate host. MANCOVA with age as the covariate for the first six CHC principal components showed extensive differences in CHC composition due to age, population, cactus, sex, and age × population, age × sex, and age × cactus interactions. Thus, understanding variation in CHC composition as adult D. mojavensis age requires information about population and host plant differences, with potential influences on patterns of mate choice, sexual selection, and sexual isolation, and ultimately how these pheromones are expressed in natural populations. Studies of drosophilid aging in the wild are badly needed. PMID:25360246

  7. Shedding Light on the Cosmic Skeleton

    Science.gov (United States)

    2009-11-01

    Astronomers have tracked down a gigantic, previously unknown assembly of galaxies located almost seven billion light-years away from us. The discovery, made possible by combining two of the most powerful ground-based telescopes in the world, is the first observation of such a prominent galaxy structure in the distant Universe, providing further insight into the cosmic web and how it formed. "Matter is not distributed uniformly in the Universe," says Masayuki Tanaka from ESO, who led the new study. "In our cosmic vicinity, stars form in galaxies and galaxies usually form groups and clusters of galaxies. The most widely accepted cosmological theories predict that matter also clumps on a larger scale in the so-called 'cosmic web', in which galaxies, embedded in filaments stretching between voids, create a gigantic wispy structure." These filaments are millions of light years long and constitute the skeleton of the Universe: galaxies gather around them, and immense galaxy clusters form at their intersections, lurking like giant spiders waiting for more matter to digest. Scientists are struggling to determine how they swirl into existence. Although massive filamentary structures have been often observed at relatively small distances from us, solid proof of their existence in the more distant Universe has been lacking until now. The team led by Tanaka discovered a large structure around a distant cluster of galaxies in images they obtained earlier. They have now used two major ground-based telescopes to study this structure in greater detail, measuring the distances from Earth of over 150 galaxies, and, hence, obtaining a three-dimensional view of the structure. The spectroscopic observations were performed using the VIMOS instrument on ESO's Very Large Telescope and FOCAS on the Subaru Telescope, operated by the National Astronomical Observatory of Japan. Thanks to these and other observations, the astronomers were able to make a real demographic study of this structure

  8. Spectroscopic Determination of Masses (and Implied Ages) for Red Giants

    Science.gov (United States)

    Ness, M.; Hogg, David W.; Rix, H.-W.; Martig, M.; Pinsonneault, Marc H.; Ho, A. Y. Q.

    2016-06-01

    The mass of a star is arguably its most fundamental parameter. For red giant stars, tracers luminous enough to be observed across the Galaxy, mass implies a stellar evolution age. It has proven to be extremely difficult to infer ages and masses directly from red giant spectra using existing methods. From the Kepler and apogee surveys, samples of several thousand stars exist with high-quality spectra and asteroseismic masses. Here we show that from these data we can build a data-driven spectral model using The Cannon, which can determine stellar masses to ∼0.07 dex from apogee dr12 spectra of red giants; these imply age estimates accurate to ∼0.2 dex (40%). We show that The Cannon constrains these ages foremost from spectral regions with CN absorption lines, elements whose surface abundances reflect mass-dependent dredge-up. We deliver an unprecedented catalog of 70,000 giants (including 20,000 red clump stars) with mass and age estimates, spanning the entire disk (from the Galactic center to R∼ 20 kpc). We show that the age information in the spectra is not simply a corollary of the birth-material abundances {{[Fe/H]}} and [α /{Fe}], and that, even within a monoabundance population of stars, there are age variations that vary sensibly with Galactic position. Such stellar age constraints across the Milky Way open up new avenues in Galactic archeology.

  9. Spectroscopic Determination of Masses (and Implied Ages) for Red Giants

    Science.gov (United States)

    Ness, M.; Hogg, David W.; Rix, H.-W.; Martig, M.; Pinsonneault, Marc H.; Ho, A. Y. Q.

    2016-06-01

    The mass of a star is arguably its most fundamental parameter. For red giant stars, tracers luminous enough to be observed across the Galaxy, mass implies a stellar evolution age. It has proven to be extremely difficult to infer ages and masses directly from red giant spectra using existing methods. From the Kepler and apogee surveys, samples of several thousand stars exist with high-quality spectra and asteroseismic masses. Here we show that from these data we can build a data-driven spectral model using The Cannon, which can determine stellar masses to ˜0.07 dex from apogee dr12 spectra of red giants; these imply age estimates accurate to ˜0.2 dex (40%). We show that The Cannon constrains these ages foremost from spectral regions with CN absorption lines, elements whose surface abundances reflect mass-dependent dredge-up. We deliver an unprecedented catalog of 70,000 giants (including 20,000 red clump stars) with mass and age estimates, spanning the entire disk (from the Galactic center to R˜ 20 kpc). We show that the age information in the spectra is not simply a corollary of the birth-material abundances {{[Fe/H]}} and [α /{Fe}], and that, even within a monoabundance population of stars, there are age variations that vary sensibly with Galactic position. Such stellar age constraints across the Milky Way open up new avenues in Galactic archeology.

  10. Amendment of the administrative skeleton provision for minimum requirements to be met by waste water discharged into bodies of water. Administrative skeleton provision on waste water of 25 November, 1992

    International Nuclear Information System (INIS)

    This provision applies to waste water to be discharged into bodies of water and whose pollution load stems mainly from the sectors indicated in appendices. Without prejudice to stricter requirements governing the execution of the Water Resources Act, the requirements to be met by the discharge of waste water, as indicated in appendices, are defined in accordance with section 7a, subsection 1, number 3 of the Water Resources Act. - The maximum concentrations indicated in appendices, for instance for waste water from brown coal briquetting plant, black coal treatment plant, petroleum refineries and flue gas scrubbers at combustion plant, relate to waste water in the discharge pipe of the waste water treatment plant. Contrary to technical rules that may apply in each instance, these concentrations must not be attained by dilution or mixing. (orig.)

  11. Electrical Aging Phenomena of Power Cables Aged by Switching Impulses

    Institute of Scientific and Technical Information of China (English)

    L.Cao; A.Zanwar; S.Grzybowski

    2013-01-01

    Due to the insufficient information regarding the aging phenomenon of cables caused by switching impulses,we aged 15 kV XLPE and EPR cable samples by 10000 switching impulses in experiments and tested them.Plus in order to compare the aging phenomenon under multi-stress conditions,additional EPR cable samples were aged by rated AC voltage and current with switching impulses superimposed.We used measurements of partial discharge parameters to monitor the cables' conditions during their aging process,and the AC breakdown voltages measurement to evaluate the cables after aging.Moreover,the Fourier transform infrared (FTIR) spectroscopy measurements revealed the changes of insulation materials after aging.The measurement results confirm that the accelerated aging of cable samples had taken place.The impacts of each individual aging factor are shown through the selected measurements and comparison.The study also helps to assess the reliability of the XLPE and EPR cables under similar condition while serving in power systems.

  12. Kaks luustikku Tartu toomkirikust: arheoloogia ja osteoloogia andmed / Two skeletons from the Tartu Cathedral Cemetery: archaeological and osteological data

    Directory of Open Access Journals (Sweden)

    Martin Malve

    2011-01-01

    Full Text Available This article deals with two case studies based on the osteological obtained in the rescue excavations in the Cathedral of Tartu in 2001 and 2008 (fig. 1. The first case study focuses on the skeleton of the child who suffered from congenital syphilis. The grave has been dated to the end of the 17th or the beginning of the 18th century. The child had been buried in the eighth nave of the northern aisle of the Cathedral (fig. 3. The grave was, according to the Christian burial traditions, west-oriented with the head facing towards the east. A Swedish 1/6 öre, minted during the reign of King Charles XI (1600–1697, was recovered from the grave. The skeleton was relatively complete and well preserved (fig. 2. Based on the dental eruption, the age at death was 9 years ± 24 months. Sexually distinctive characteristics had not developed, and thus it was impossible to determine the sex of the child. Both the microscopical and radiological analyses revealed that the skeleton had indicators of congenital syphilis. Damage from gummatous osteomyelitis and periostitis were visible on the skull and on the axial and appendicular skeleton (fig. 6, while Hutchinson’s incisors and Mulberry molars were present among the teeth. Deformations and damage on the bones suggest that the child had suffered from the disease for quite a long time.The second case study discusses a beheaded man found from the eighth nave in the southern aisle of the Cathedral (fig. 3. The grave pit had a depth of 80 cm from the medieval floor surface of the church, which indicates that the burial dates from the Middle Ages. Also, the head of the deceased pointed to the west.The bones were well preserved (fig. 6. Sex was determined from the characteristics of the skull and the length of the right humerus. Calcification of the cranial sutures and cartilages suggests that the age of the man at death was probably 50+. Macroscopic examination of the skeleton revealed that the man had suffered

  13. Spectroscopic determination of masses (and implied ages) for red giants

    Science.gov (United States)

    Ness, Melissa; Hogg, David W.; Rix, Hans-Walter; Martig, Marie; Ho, Anna

    2016-01-01

    The mass of a star is arguably its most fundamental parameter and for red giant stars it implies a stellar evolution age. Stellar masses and ages have never been derived directly from spectra of red giants. However, using the APOGEE Kepler sample of stars, (the APOKASC sample), with high-quality spectra and astroseismic masses, we can build a data-driven spectral model using THE CANNON (arXiv:1501.07604) to infer stellar mass and therefore age from stellar spectra. We determine stellar masses to 0.07 dex from APOGEE DR12 spectra of red giants; these imply age estimates accurate to 0.2 dex (40 percent). THE CANNON constrains the ages foremost from spectral regions with particular absorption lines, elements whose surface abundances reflect mass-dependent dredge-up. We deliver an unprecedented catalog of 85,000 giants (including 20,000 red-clump stars) with mass and age estimates, spanning the entire disk (from the Galactic center to R ˜ 20 kpc). Such stellar age constraints across the Milky Way open up new avenues in Galactic archeology.

  14. Determinants of active aging among the elderly Portuguese population

    OpenAIRE

    Calha, António

    2014-01-01

    Our aim in this communication is to contribute to the characterization of motor skills of the Portuguese elderly population, determining their relationship with age and with the subjective health status. We characterized the capabilities of gross motor skills (GMS) and fine motor skills (FMS) based on two indices that aggregate various indicators.

  15. Biological psychological and social determinants of old age: bio-psycho-social aspects of human aging.

    Science.gov (United States)

    Dziechciaż, Małgorzata; Filip, Rafał

    2014-01-01

    The aging of humans is a physiological and dynamic process ongoing with time. In accordance with most gerontologists' assertions it starts in the fourth decade of life and leads to death. The process of human aging is complex and individualized, occurs in the biological, psychological and social sphere. Biological aging is characterized by progressive age-changes in metabolism and physicochemical properties of cells, leading to impaired self-regulation, regeneration, and to structural changes and functional tissues and organs. It is a natural and irreversible process which can run as successful aging, typical or pathological. Biological changes that occur with age in the human body affect mood, attitude to the environment, physical condition and social activity, and designate the place of seniors in the family and society. Psychical ageing refers to human awareness and his adaptability to the ageing process. Among adaptation attitudes we can differentiate: constructive, dependence, hostile towards others and towards self attitudes. With progressed age, difficulties with adjustment to the new situation are increasing, adverse changes in the cognitive and intellectual sphere take place, perception process involutes, perceived sensations and information received is lowered, and thinking processes change. Social ageing is limited to the role of an old person is culturally conditioned and may change as customs change. Social ageing refers to how a human being perceives the ageing process and how society sees it. PMID:25528930

  16. Skeletonized Least Squares Wave Equation Migration

    KAUST Repository

    Zhan, Ge

    2010-10-17

    The theory for skeletonized least squares wave equation migration (LSM) is presented. The key idea is, for an assumed velocity model, the source‐side Green\\'s function and the geophone‐side Green\\'s function are computed by a numerical solution of the wave equation. Only the early‐arrivals of these Green\\'s functions are saved and skeletonized to form the migration Green\\'s function (MGF) by convolution. Then the migration image is obtained by a dot product between the recorded shot gathers and the MGF for every trial image point. The key to an efficient implementation of iterative LSM is that at each conjugate gradient iteration, the MGF is reused and no new finitedifference (FD) simulations are needed to get the updated migration image. It is believed that this procedure combined with phase‐encoded multi‐source technology will allow for the efficient computation of wave equation LSM images in less time than that of conventional reverse time migration (RTM).

  17. Co-occurrence Feature Learning for Skeleton based Action Recognition using Regularized Deep LSTM Networks

    OpenAIRE

    Zhu, Wentao; Lan, Cuiling; Xing, Junliang; Zeng, Wenjun; Li, Yanghao; Shen, Li; Xie, Xiaohui

    2016-01-01

    Skeleton based action recognition distinguishes human actions using the trajectories of skeleton joints, which provide a very good representation for describing actions. Considering that recurrent neural networks (RNNs) with Long Short-Term Memory (LSTM) can learn feature representations and model long-term temporal dependencies automatically, we propose an end-to-end fully connected deep LSTM network for skeleton based action recognition. Inspired by the observation that the co-occurrences o...

  18. Osteogenic potential of bone-lining cells in the adult skeleton

    International Nuclear Information System (INIS)

    Radiation-induced osteogenic sarcomas are believed to arise from proliferating osteogenic precursor cells. The identity and location of these cells in the adult skeleton is not well understood. In order to determine reliable cell dose estimates, it is important to determine the osteogenic pathway in the adult skeleton. Bone-lining cells (BLCs) cover inactive endosteal surfaces in the adult skeleton of long-lived animals. BLCs are flat elongated cells which are directly apposed to the bone surface. They have cell processes extending into canaliculi and have gap junctions at some contacts with other bone-lining cells. The morphology of the bone-lining cell and its proximity to the bone surface can only be resolved at the ultrastructural level. These cells are a distinct morphologic phenotype but have been referred to by a variety of names including resting osteoblasts, surface osteocytes, and flattened mesenchymal cells. The BLC, as a distinct phenotype, should not be confused with the more descriptive term cells lining the bone surface of bone lining cells, sometimes used to include any cell near the bone. The purpose of the study was to determine what role, if any, the bone-lining cells have in the osteogenic process. Do these cells proliferate and contribute to the population of osteoblasts?

  19. Determination of U-Pb age and rare earth element concentrations of zircons from Cenozoic intrusions in northeastern China by laser ablation ICP-MS

    Institute of Scientific and Technical Information of China (English)

    YUAN Honglin; WU Fuyuan; GAO Shan; LIU Xiaoming; XU Ping; SUN Deyou

    2003-01-01

    Using the in situ zircon U-Pb dating method of LA-ICPMS, we analyzed the 31 Ma old SHRIMP U-Pb age of the Yongsheng nepheline syenite from southern Jilin Province under different spot sizes. The obtained ages are comparable with that of SHRIMP in both accuracy and precision. The age is also identical to that of the Yinmawanshan gabbro from the Liaodong Peninsula within error. Both the Yongsheng nepheline syenite and the Yinmawanshan gabbro represent the youngest known exposed intrusions in northeastern and even eastern China. The results indicate the Eocene mantle-derived magmatic underplating, and the rapid crustal uplifting of this region since 30 Ma. The analyses also document extremely high LREE concentrations and relatively flat REE patterns for the zircons from the Yongsheng nepheline syenite, which represent a new type of zircon REE pattern.

  20. Age determination in roe deer - a new approach to tooth wear evaluated on known age individuals

    DEFF Research Database (Denmark)

    Høye, Toke Thomas

    2006-01-01

    A novel, simple, and objective method is presented for ageing roe deer Capreolus capreolus (Linnaeus, 1758) evaluated on 471 lower jaws from roe deer of known age (351 with permanent premolars). It is based on tooth eruption patterns and presence/absence of wear characters in jaws from roe deer...... originate from two separated Danish roe deer populations exposed to contrasting habitats, but no difference in wear rate is found between populations. Thus, previous concern about the validity of age determination methods based on tooth wear may have been overstated. The findings demonstrate that objective...

  1. Dental maturity of Saudi children: Role of ethnicity in age determination

    International Nuclear Information System (INIS)

    Demirjian's dental maturity scores and curves have been widely used for human age determination. Several authors have reported considerable differences between the true and estimated age based on the Demirjian curves, which have been accounted for by ethnicity. The purpose of the current study was to assess the role of ethnicity-specific dental maturation curves in age estimation of Saudi children. A sample of 452 healthy Saudi children aged 4 to 14 years were aged based on the original French-Canadian Demirjian curves and several modified Demirjian curves specified for certain ethnic groups: Saudi, Kuwaiti, Polish, Dutch, Pakistani, and Belgian. One-way ANOVA and a post hoc Scheffe's test were used to assess the differences between chronological age and dental age estimated by the different curves (P<0.05). The curves designed for Dutch, Polish, Saudi, and Belgian (5th percentile) populations had a significantly lower error in estimating age than the original French-Canadian and Belgian (50th percentile) curves. The optimal curve for males was the Saudi one, with a mean absolute difference between estimated age and chronological age of 8.6 months. For females, the optimal curve was the Polish one, with a mean absolute difference of 7.4 months. It was revealed that accurate age determination was not related to certain ethnicity-specific curves. We conclude that ethnicity might play a role in age determination, but not a principal one.

  2. Dental maturity of Saudi children: Role of ethnicity in age determination

    Energy Technology Data Exchange (ETDEWEB)

    Baghdadi, Ziad D. [Dept. of Preventive Dentistry, Riyadh Colleges of Dentistry and Pharmacy, Riyadh (Saudi Arabia)

    2013-12-15

    Demirjian's dental maturity scores and curves have been widely used for human age determination. Several authors have reported considerable differences between the true and estimated age based on the Demirjian curves, which have been accounted for by ethnicity. The purpose of the current study was to assess the role of ethnicity-specific dental maturation curves in age estimation of Saudi children. A sample of 452 healthy Saudi children aged 4 to 14 years were aged based on the original French-Canadian Demirjian curves and several modified Demirjian curves specified for certain ethnic groups: Saudi, Kuwaiti, Polish, Dutch, Pakistani, and Belgian. One-way ANOVA and a post hoc Scheffe's test were used to assess the differences between chronological age and dental age estimated by the different curves (P<0.05). The curves designed for Dutch, Polish, Saudi, and Belgian (5th percentile) populations had a significantly lower error in estimating age than the original French-Canadian and Belgian (50th percentile) curves. The optimal curve for males was the Saudi one, with a mean absolute difference between estimated age and chronological age of 8.6 months. For females, the optimal curve was the Polish one, with a mean absolute difference of 7.4 months. It was revealed that accurate age determination was not related to certain ethnicity-specific curves. We conclude that ethnicity might play a role in age determination, but not a principal one.

  3. Determinants of iron accumulation in the normal aging brain.

    Science.gov (United States)

    Pirpamer, Lukas; Hofer, Edith; Gesierich, Benno; De Guio, François; Freudenberger, Paul; Seiler, Stephan; Duering, Marco; Jouvent, Eric; Duchesnay, Edouard; Dichgans, Martin; Ropele, Stefan; Schmidt, Reinhold

    2016-07-01

    In a recent postmortem study, R2* relaxometry in gray matter (GM) of the brain has been validated as a noninvasive measure for iron content in brain tissue. Iron accumulation in the normal aging brain is a common finding and relates to brain maturation and degeneration. The goal of this study was to assess the determinants of iron accumulation during brain aging. The study cohort consisted of 314 healthy community-dwelling participants of the Austrian Stroke Prevention Study. Their age ranged from 38-82 years. Quantitative magnetic resonance imaging was performed on 3T and included R2* mapping, based on a 3D multi-echo gradient echo sequence. The median of R2* values was measured in all GM regions, which were segmented automatically using FreeSurfer. We investigated 25 possible determinants for cerebral iron deposition. These included demographics, brain volume, lifestyle factors, cerebrovascular risk factors, serum levels of iron, and single nucleotide polymorphisms related to iron regulating genes (rs1800562, rs3811647, rs1799945, and rs1049296). The body mass index (BMI) was significantly related to R2* in 15/32 analyzed brain regions with the strongest correlations found in the amygdala (p = 0.0091), medial temporal lobe (p = 0.0002), and hippocampus (p ≤ 0.0001). Further associations to R2* values were found in deep GM for age and smoking. No significant associations were found for gender, GM volume, serum levels of iron, or iron-associated genetic polymorphisms. In conclusion, besides age, the BMI and smoking are the only significant determinants of brain iron accumulation in normally aging subjects. Smoking relates to iron deposition in the basal ganglia, whereas higher BMI is associated with iron content in the neocortex following an Alzheimer-like distribution. PMID:27255824

  4. DPIV Measurements of Olympic Skeleton Athletes

    CERN Document Server

    Leong, Chia Min; Wu, Vicki; Wei, Timothy; Peters, Steve

    2010-01-01

    The Olympic sport of skeleton involves an athlete riding a small sled face first down a bobsled track at speeds up to 130 km/hr. In these races, the difference between gold and missing the medal stand altogether can be hundredths of a second per run. As such, reducing aerodynamic drag through proper body positioning is of first order importance. To better study the flow behavior and to improve the performance of the athletes, we constructed a mock section of a bobsled track which was positioned at the exit of an open loop wind tunnel. DPIV measurements were made along with video recordings of body position to aid the athletes in determining their optimal aerodynamic body position. In the fluid dynamics video shown, the athlete slowly raised his head while DPIV measurements were made behind the helmet in the separated flow region.

  5. Bisabocurcumin, a new skeleton curcuminoid from the rhizomes of Curcuma longa L.

    Institute of Scientific and Technical Information of China (English)

    Yun Chuan Xiao; Jing Xie; Min Yu; Miao Liu; Jian Ran; Zhen Xi; Wei Li; Jing Huang

    2011-01-01

    A new skeleton bisabolane-type sesquiterpene curcuminoid, bisabocurcumin (1), along with 5 known compounds, curcumin (2), demethoxycurcumin (3), bidemethoxycurcumin (4), (1E,4E)-l,5-bis(4-hydroxy-3-methoxyphenyl)-penta-1,4-dien-3-one (5), and (1E,4E)-1-(4-hydroxy-3-methoxyphenyl)-5-(4-hydroxy phenyl-)-penta-1,4-dien-3-one (6) were isolated from the rhizomes of Curcuma longa L. Their structures were determined on the basis of spectroscopic analysis. Bisabocurcumin (1) is firstly obtained from nature with a new skeleton combined by a bisabolane-type sesquiterpene and a 1,7-diphenylheptanoid through a C-C bond.

  6. Distribution of injected plutonium in the skeleton and certain soft tissues

    International Nuclear Information System (INIS)

    The burden and macrodistribution of plutonium in the skeleton and its concentration in certain soft tissues have been determined in the remains of a woman who received plutonium by injection. The method of analysis was alpha spectrometric--isotopic dilution. The skeletal burden was 54 +- 2% of the amount injected. As expected, the concentrations in bones that are primarily trabecular were much higher than those that are primarily cortical; the ratio of the concentration in the bodies of the thoracic vertebrae to that in the diaphysis of the tibia was 40. The bones of the skull and the clavicle are quite representative of the entire skeleton. The concentrations in soft tissue are a factor of about 100 lower than those in bone. The concentration in hair increases markedly with the distance from the scalp

  7. Differences by Age Groups in Health Care Spending

    OpenAIRE

    Fisher, Charles R.

    1980-01-01

    This paper presents differences by age in health care spending by type of expenditure and by source of funds through 1978. Use of health care services generally increases with age. The average health bill reached $2,026 for the aged in 1978, $764 for the intermediate age group, and $286 for the young. Biological, demographic, and policy factors determine each age group's share of health spending. Public funds financed over three-fifths of the health expenses of the aged, with Medicare and Med...

  8. Vortex and strain skeletons in Eulerian and Lagrangian frames.

    Science.gov (United States)

    Sahner, Jan; Weinkauf, Tino; Teuber, Nathalie; Hege, Hans-Christian

    2007-01-01

    We present an approach to analyze mixing in flow fields by extracting vortex and strain features as extremal structures of derived scalar quantities that satisfy a duality property: they indicate vortical as well as high-strain (saddletype) regions. Specifically, we consider the Okubo-Weiss criterion and the recently introduced MZ-criterion. While the first is derived from a purely Eulerian framework, the latter is based on Lagrangian considerations. In both cases high values indicate vortex activity whereas low values indicate regions of high strain. By considering the extremal features of those quantities, we define the notions of a vortex and a strain skeleton in a hierarchical manner: the collection of maximal 0D, 1D and 2D structures assemble the vortex skeleton; the minimal structures identify the strain skeleton. We extract those features using scalar field topology and apply our method to a number of steady and unsteady 3D flow fields. PMID:17622681

  9. Age determination of 15 old to intermediate-age small Magellanic cloud star clusters

    International Nuclear Information System (INIS)

    We present color-magnitude diagrams in the V and I bands for 15 star clusters in the Small Magellanic Cloud (SMC) based on data taken with the Very Large Telescope (VLT, Chile). We selected these clusters from our previous work, wherein we derived cluster radial velocities and metallicities from calcium II infrared triplet (CaT) spectra also taken with the VLT. We discovered that the ages of six of our clusters have been appreciably underestimated by previous studies, which used comparatively small telescopes, graphically illustrating the need for large apertures to obtain reliable ages of old and intermediate-age SMC star clusters. In particular, three of these clusters, L4, L6, and L110, turn out to be among the oldest SMC clusters known, with ages of 7.9 ± 1.1, 8.7 ± 1.2, and 7.6 ± 1.0 Gyr, respectively, helping to fill a possible 'SMC cluster age gap'. Using the current ages and metallicities from Parisi et al., we analyze the age distribution, age gradient, and age-metallicity relation (AMR) of a sample of SMC clusters measured homogeneously. There is a suggestion of bimodality in the age distribution but it does not show a constant slope for the first 4 Gyr, and we find no evidence for an age gradient. Due to the improved ages of our cluster sample, we find that our AMR is now better represented in the intermediate/old period than we had derived in Parisi et al., where we simply took ages available in the literature. Additionally, clusters younger than ∼4 Gyr now show better agreement with the bursting model of Pagel and Tautvaišienė, but we confirm that this model is not a good representation of the AMR during the intermediate/old period. A more complicated model is needed to explain the SMC chemical evolution in that period.

  10. Age determination of 15 old to intermediate-age small Magellanic cloud star clusters

    Energy Technology Data Exchange (ETDEWEB)

    Parisi, M. C.; Clariá, J. J.; Piatti, A. E. [Observatorio Astronómico, Universidad Nacional de Córdoba, Laprida 854, Córdoba, CP 5000 (Argentina); Geisler, D.; Leiton, R. [Departamento de Astronomía, Universidad de Concepción, Casilla 160-C, Concepción (Chile); Carraro, G. [European Southern Observatory, Casilla 19001, Santiago de Chile (Chile); Costa, E. [Universidad de Chile, Casilla 36-D, Santiago de Chile (Chile); Grocholski, A. J. [Department of Physics and Astronomy, Louisiana State University, 202 Nicholson Hall, Tower Drive, Baton Rouge, LA 70803-4001 (United States); Sarajedini, A., E-mail: celeste@oac.uncor.edu, E-mail: claria@oac.uncor.edu, E-mail: andres@oac.uncor.edu, E-mail: dgeisler@astro-udec.cl, E-mail: roger.leiton@astro-udec.cl, E-mail: gcarraro@eso.org, E-mail: costa@das.uchile.cl, E-mail: grocholski@phys.lsu.edu, E-mail: ata@astro.ufl.edu [Department of Astronomy, University of Florida, P.O. Box 112055, Gainesville, FL 32611 (United States)

    2014-04-01

    We present color-magnitude diagrams in the V and I bands for 15 star clusters in the Small Magellanic Cloud (SMC) based on data taken with the Very Large Telescope (VLT, Chile). We selected these clusters from our previous work, wherein we derived cluster radial velocities and metallicities from calcium II infrared triplet (CaT) spectra also taken with the VLT. We discovered that the ages of six of our clusters have been appreciably underestimated by previous studies, which used comparatively small telescopes, graphically illustrating the need for large apertures to obtain reliable ages of old and intermediate-age SMC star clusters. In particular, three of these clusters, L4, L6, and L110, turn out to be among the oldest SMC clusters known, with ages of 7.9 ± 1.1, 8.7 ± 1.2, and 7.6 ± 1.0 Gyr, respectively, helping to fill a possible 'SMC cluster age gap'. Using the current ages and metallicities from Parisi et al., we analyze the age distribution, age gradient, and age-metallicity relation (AMR) of a sample of SMC clusters measured homogeneously. There is a suggestion of bimodality in the age distribution but it does not show a constant slope for the first 4 Gyr, and we find no evidence for an age gradient. Due to the improved ages of our cluster sample, we find that our AMR is now better represented in the intermediate/old period than we had derived in Parisi et al., where we simply took ages available in the literature. Additionally, clusters younger than ∼4 Gyr now show better agreement with the bursting model of Pagel and Tautvaišienė, but we confirm that this model is not a good representation of the AMR during the intermediate/old period. A more complicated model is needed to explain the SMC chemical evolution in that period.

  11. Spectroscopic determination of masses (and implied ages) for red giants

    CERN Document Server

    Ness, M; Rix, H-W; Martig, M; Pinsonneault, Marc H; Ho, A Y Q

    2015-01-01

    The mass of a star is arguably its most fundamental parameter. For red giant stars, tracers luminous enough to be observed across the Galaxy, mass implies a stellar evolution age. It has proven to be extremely difficult to infer ages and masses directly from red giant spectra using existing methods. From the KEPLER and APOGEE surveys, samples of several thousand stars exist with high-quality spectra and asteroseismic masses. Here we show that from these data we can build a data-driven spectral model using The Cannon, which can determine stellar masses to $\\sim$ 0.07 dex from APOGEE DR12 spectra of red giants; these imply age estimates accurate to $\\sim$ 0.2 dex (40 percent). We show that The Cannon constrains these ages foremost from spectral regions with CN absorption lines, elements whose surface abundances reflect mass-dependent dredge-up. We deliver an unprecedented catalog of 80,000 giants (including 20,000 red-clump stars) with mass and age estimates, spanning the entire disk (from the Galactic center t...

  12. Absolute age determination of quaternary fault and formation

    Energy Technology Data Exchange (ETDEWEB)

    Cheong, Chang Sik; Lee, Kwang Sik; Choi, Man Sik [Korea Basic Science Institute, Taejon (Korea, Republic of)] (and others)

    2003-03-15

    Rb-Sr and K-Ar dating results for the fault rocks suggest the occurrence of recurrent fault activity around 80-95 Ma, 70 Ma, 50 Ma, 30 Ma and 23 Ma along the Yangsan fault zone. The apparent K-Ar ages tend to be older than Rb-Sr ages, probably indicating the effect of excess radiogenic Ar, which will be furthur investigated by Ar-Ar method. The OSL SAR protocol using 220 .deg. C cut-heat yields reproducible and stratigraphically consistent OSL ages ranging from 71 ka to 48 ka for beach deposits of the marine terrace No 2. The apparent OSL ages for the marine terrace No 3 range from 92 ka to 61 ka. These ages constrain the minimum age of the platform considering the underestimation effect resulted from deposition underwater. Therefore we regard the formation age of the terrace No 3 as MIS(Marine Isotopic Stage) 5c or 5e. Rb-Sr and K-Ar dating results for the fault rocks suggest the occurrence of recurrent fault activity around 40 Ma, 30 Ma and 23 Ma along the Ulsan fault zone. Relatively young (< 10 Ma) fault activities are recognized in the Oesa, Janghangri and Wonwonsa sites.

  13. The use of radionuclide skeleton visualization method in hygienic studies

    International Nuclear Information System (INIS)

    Inhalation, intragastric and combined effect of two cadmium compounds on rats is studied. Investigations are performed by biochemical methods and the method of radionuclide visualization of the skeleton which was performed delta hours after RPP introduction in gamma-chamber with computer tape recording for the following mathematical treatment of the image. Using the method of radionuclide skeleton visualization pronounced quantitative characteristics of changes in the bone tissue are obtained, it is found that dose dependence of these changes is especially important when estimating the complex effect. Biochemical methods, are used to find alterations, however they have not been assessed quantitatively

  14. Determination on the mineral salt content of the peripheral skeleton (ulna and calcaneus) in thyroid patients using /sup 125/I gamma-radiation absorption measurement. Investigations on the dependence of the measured mineral salt values of various influencing parameters

    Energy Technology Data Exchange (ETDEWEB)

    Kotz, F.

    1979-07-17

    The bone mineral salt content (BMC) has been determined in this work for 69 female and 14 male hyperthyroid patients and 13 euthyroid adenoma patients by means of I/sup 125/ gamma-radiation absorption measurement. It could be seen by comparison to healthy patients that hyperthyroid patients lie statistically significantly below the corresponding age and sex standard values, whilst the euthyroid adenoma female patients' values are found in the BMC normal range. It was furthermore shown that the menopause did not essentially influence the BMC values of Ulna and calcaneus. A further chapter treats the dependence of the BMC values on the hyperthyroidosis duration. Queries on whether the height of the BMC values depend on the f T/sub 4/ index were treated, as well as whether patients showing different extents of clinical hyperthyroid indications, statistically significantly differ even with average BMC. A comparison of the average BMC values of pretreated and untreated hyperthyroidosis patients was made.

  15. Right to Left Ventricular Diameter Ratio ≥0.42 is the Warning Flag for Suspecting Atrial Septal Defect in Preschool Children: Age- and Body Surface Area-Related Reference Values Determined by M-Mode Echocardiography.

    Science.gov (United States)

    Hashimoto, Ikuo; Watanabe, Kazuhiro; Ichida, Fukiko

    2016-04-01

    It is not always easy to observe and screen atrial septal defects (ASD) using echocardiography. In addition, there are no established echocardiographic reference indices for screening patients with ASDs. We retrospectively reviewed our database and recruited 151 isolated ASD patients and 2769 healthy subjects. In total, 307 echocardiographic studies were performed for ASD patients. Surgical repairs were done in 75 of the ASD patients. The ratio of right to left ventricular end-diastolic dimensions (RVD/LVD), which was determined by M-mode echocardiography, was used as an index of RV dilatation. After obtaining age- and body surface area (BSA)-related RVD/LVD nomograms in healthy subjects, we calculated the z-scores of RVD/LVD for all subjects and obtained the optimal cut-off values to differentiate patients with ASD from healthy subjects. The optimal cut-off values were high in neonates and gradually decreased with an increase in the age and BSA, but were almost constant in children aged >4 years or whose BSA was >0.65 m(2). The cut-off values of RVD/LVD for suspected ASD were ≥0.42 in children aged >4 years or those whose BSA was >0.65 m(2). Those for an ASD operation were ≥0.46 in those whose BSA > 0.65 m(2). The RVD/LVD determined by M-mode echocardiography is a useful index to evaluate RV dilatation in patients with ASDs. The RVD/LVD ≥ 0.42 is the warning flag for suspecting ASD in preschool children and that ≥0.46 may be a clinical important sign to determine ASD operation. PMID:26700967

  16. Age determinations of the Zoetlief Group: a Ventersdorp Supergroup correlative

    International Nuclear Information System (INIS)

    Rb-Sr, Pb-Pb and single zircon dating of the Kareefontein Quartz Phorphyry, northeastern Cape Province, South Africa, confirm the correlation proposed by SACS (1980) between the Zoetlief Group and the Ventersdorp Supergroup. Rb-Sr and Pb-Pb whole-rock ages of ca. 2 350 to 1 900 Ma for the Kareefontein permit no definitive interpretation but are nevertheless similar to the age patterns for the Ventersdorp and support the correlation. The clearest evidence is the almost perfect match between the Kareefontein single zircon Pb evaporation date of 2 714 ± 3 Ma and zircon SHRIMP dates for the Makwassie Quartz Porphyry and Klipriviersberg Formation of the Ventersdorp. Nd model ages of 3.05 to 3.22 Ga are interpreted as the minimum age of formation of the crustal protolith parental to the Kareefontein Quartz Porphyry melt. 5 figs., 4 tabs., 31 refs

  17. Quality evaluation of aged concrete by ultrasound

    Science.gov (United States)

    Tavossi, H. M.; Tittmann, Bernhard R.; Cohen-Tenoudji, Frederic

    1999-02-01

    The velocity, attenuation and scattering of ultrasonic waves measured in concrete, mortar and cement structures can be used to evaluate their quality with weathering and aging. In this investigation the hardening of concrete mixture with time is monitored by ultrasonic waves under different conditions of temperature and water to cement ratio. The measured ultrasonic parameters can then be utilized to determine the final quality of the completely cured concrete structure from initial measurement. The quality of a concrete structure is determined by its resistance to compression and its rigidity, which should be within the acceptable values required by the design specifications. The internal and external flaws that could lower its strength can also be detected by ultrasonic technique. Aging process of concrete by weathering can be simulated in the laboratory by subjecting the concrete to extremes of cold and hot cycles in the range of temperatures normally encountered in summer and winter. In this research ultrasonic sensors in low frequency range of 40 to 100 kHz are used to monitor the quality of concrete. Ultrasonic pulses transmitted through the concrete sample are recorded for analysis in time and frequency domains. ULtrasonic waves penetration in concrete of the order of few feet has been achieved in laboratory. Data analyses on ultrasonic signal velocity, spectral content, phase and attenuation, can be utilized to evaluate, in situ, the quality and mechanical strength of concrete.

  18. Biology of bone and how it orchestrates the form and function of the skeleton

    Science.gov (United States)

    Sommerfeldt, D. W.; Rubin, C. T.

    2001-01-01

    The principal role of the skeleton is to provide structural support for the body. While the skeleton also serves as the body's mineral reservoir, the mineralized structure is the very basis of posture, opposes muscular contraction resulting in motion, withstands functional load bearing, and protects internal organs. Although the mass and morphology of the skeleton is defined, to some extent, by genetic determinants, it is the tissue's ability to remodel--the local resorption and formation of bone--which is responsible for achieving this intricate balance between competing responsibilities. The aim of this review is to address bone's form-function relationship, beginning with extensive research in the musculoskeletal disciplines, and focusing on several recent cellular and molecular discoveries which help understand the complex interdependence of bone cells, growth factors, physical stimuli, metabolic demands, and structural responsibilities. With a clinical and spine-oriented audience in mind, the principles of bone cell and molecular biology and physiology are presented, and an attempt has been made to incorporate epidemiologic data and therapeutic implications. Bone research remains interdisciplinary by nature, and a deeper understanding of bone biology will ultimately lead to advances in the treatment of diseases and injuries to bone itself.

  19. The 'Prof. Dr. Rómulo Lambre' Collection: an Argentinian sample of modern skeletons.

    Science.gov (United States)

    Salceda, S A; Desántolo, B; Mancuso, R García; Plischuk, M; Inda, A M

    2012-08-01

    This paper describes the 'Prof. Dr. Rómulo Lambre' skeletal collection. The Lambre Collection is housed in the School of Medical Sciences of the National University of La Plata and it consists of skeletal remains ceded by the Municipal Cemetery of La Plata. The collection has more than four hundred skeletons, with information on age, sex, nationality, date and cause of death. It was created for teaching and research purposes in compliance with current legislation, and its management meets guidelines specified in the Declaration of the Argentinian Association for Biological Anthropology on Research Ethics on Human Remains (2007). PMID:22769855

  20. Work characteristics and determinants of job satisfaction in four age groups: university employees' point of view.

    NARCIS (Netherlands)

    Bos, J.T.; Donders, N.C.G.M.; Bouwman-Brouwer, K.M.; Gulden, J.W.J. van der

    2009-01-01

    PURPOSE: To investigate (a) differences in work characteristics and (b) determinants of job satisfaction among employees in different age groups. METHODS: A cross-sectional questionnaire was filled in by 1,112 university employees, classified into four age groups. (a) Work characteristics were analy

  1. Physical Attractiveness, Age, and Sex as Determinants of Reactions to Resumes.

    Science.gov (United States)

    Quereshi, M. Y.; Kay, Janet P.

    1986-01-01

    Physical attractiveness, age, and sex were manipulated to determine their effect on the evaluation of 54 hypothetical applicants' resumes for three different jobs by 60 Master's in Business Administration students. Physical attractiveness favorably influenced the suitability ratings for all jobs; raters' sex and age were not significant but…

  2. Spatially variant morphological restoration and skeleton representation.

    Science.gov (United States)

    Bouaynaya, Nidhal; Charif-Chefchaouni, Mohammed; Schonfeld, Dan

    2006-11-01

    The theory of spatially variant (SV) mathematical morphology is used to extend and analyze two important image processing applications: morphological image restoration and skeleton representation of binary images. For morphological image restoration, we propose the SV alternating sequential filters and SV median filters. We establish the relation of SV median filters to the basic SV morphological operators (i.e., SV erosions and SV dilations). For skeleton representation, we present a general framework for the SV morphological skeleton representation of binary images. We study the properties of the SV morphological skeleton representation and derive conditions for its invertibility. We also develop an algorithm for the implementation of the SV morphological skeleton representation of binary images. The latter algorithm is based on the optimal construction of the SV structuring element mapping designed to minimize the cardinality of the SV morphological skeleton representation. Experimental results show the dramatic improvement in the performance of the SV morphological restoration and SV morphological skeleton representation algorithms in comparison to their translation-invariant counterparts. PMID:17076415

  3. The origin of the vertebrate skeleton

    Science.gov (United States)

    Pivar, Stuart

    2011-01-01

    The anatomy of the human and other vertebrates has been well described since the days of Leonardo da Vinci and Vesalius. The causative origin of the configuration of the bones and of their shapes and forms has been addressed over the ensuing centuries by such outstanding investigators as Goethe, Von Baer, Gegenbauer, Wilhelm His and D'Arcy Thompson, who sought to apply mechanical principles to morphogenesis. However, no coherent causative model of morphogenesis has ever been presented. This paper presents a causative model for the origin of the vertebrate skeleton, based on the premise that the body is a mosaic enlargement of self-organized patterns engrained in the membrane of the egg cell. Drawings illustrate the proposed hypothetical origin of membrane patterning and the changes in the hydrostatic equilibrium of the cytoplasm that cause topographical deformations resulting in the vertebrate body form.

  4. AGE DETERMINATION FOR 346 NEARBY STARS IN THE HERSCHEL DEBRIS SURVEY

    International Nuclear Information System (INIS)

    DEBRIS is a flux-limited survey of nearby stars (spectral types A-M) for evidence of debris disks with the Herschel Space Observatory. One goal of the survey is to determine disk incidence as a function of various stellar parameters. Understanding debris disk evolution depends on knowledge of the precise age of stars around which these debris disks are found. However, finding ages for field stars is notoriously difficult. Furthermore, in an unbiased sample like DEBRIS, one is working with stars across many spectral types. This requires a multi-method approach to age determination. In this paper, we outline several methods of age determination broken down by spectral type, including some strengths and limitations of each method. In total, we were able to calculate ages for 263 of 274 F-, G-, and K-type stars, and all 83 A-type stars in the DEBRIS sample.

  5. Study on Virtual Human Skeleton System

    Institute of Scientific and Technical Information of China (English)

    郭巧; 李亦

    2004-01-01

    A solution of virtual human skeleton system is proposed. Some issues on integration of anatomical geometry, biodynamics and computer animation are studied. The detailed skeleton system model that incorporates the biodynamic and geometric characteristics of a human skeleton system allows some performance studies in greater detail than that performed before. It may provide an effective and convenient way to analyze and evaluate the movement performance of a human body when the personalized anatomical data are used in the models. An example shows that the proposed solution is effective for the stated problems.

  6. /sup 13/C-NMR of diterpenes with rosane skeleton

    Energy Technology Data Exchange (ETDEWEB)

    da Cunha Pinto, A.; Garcez, W.S.; Ficara, M.L.G.; Vasconcelos, T.C.; Pereira, A.L.; Gomes, L.N.L.F.; Frechiani, M.doC.; Patitucci, M.L. (Rio de Janeiro Univ. (Brazil). Nucleo de Pesquisas de Produtos Naturais)

    1982-03-01

    /sup 13/C-NMR data of three diterpenoids with rosane skeleton isolated from Vellozia candida Mikan, and of their oxidated and acetylated derivatives are presented. The main effects caused by small structural differences are discussed and used in the assignment of the chemical shifts of all carbons.

  7. The use of dental radiography in age determination: Concepts and methods

    Directory of Open Access Journals (Sweden)

    Seyed Amir Hossein Mirhashemi

    2014-06-01

    Full Text Available   The need to identify and determine the age of the unidentified dead person s or accident victims of natural disasters is clear. Also, some remedial measures in the field of orthodontics and pediatric dentistry depend on knowing the patient’s physiological age. Previous studies suggested that dental age have a good correlation with physiological age more than skeletal or o ther common methods of age determination. Among the various methods used to determine dental age , dental radiography provides wide facilities for clinicians. Being noninvasive and the ability of performing the technique on live subjects as well as simplicity and low cost and reliable results , have led researchers to investigate further on that . The formation and calcification process of teeth and changes during aging has been regarded by many, leading to introduce various methods in which the field. In this study, 36 related articles were achieved by searching PUBMED, Science Direct and Google Scholar resources and discussed. Provided what diversified means of determining age using dental radiographs is encouraged , it is recommended to be not restricted to use only one of the methods because the multilateral approach is more reliable.

  8. Test Plan to Update SRS High Level Waste Tank Material Properties Database by Determining Synergistic Effects of Dynamic Strain Aging and Stress Corrosion Cracking

    International Nuclear Information System (INIS)

    The structural integrity of High Level Waste tanks is defined by the demonstrated confinement of the waste by the tank structure under design basis conditions. a comprehensive test plan is presented here to develop a mechanical and corrosion properties database to develop a fundamental understanding of the synergistic effects of DSA and SCC due to high temperature service of the HLW tanks

  9. Test Plan to Update SRS High Level Waste Tank Material Properties Database by Determining Synergistic Effects of Dynamic Strain Aging and Stress Corrosion Cracking; TOPICAL

    International Nuclear Information System (INIS)

    The structural integrity of High Level Waste tanks is defined by the demonstrated confinement of the waste by the tank structure under design basis conditions. a comprehensive test plan is presented here to develop a mechanical and corrosion properties database to develop a fundamental understanding of the synergistic effects of DSA and SCC due to high temperature service of the HLW tanks

  10. Effect of dietary, social, and lifestyle determinants of accelerated aging and its common clinical presentation: A survey study

    OpenAIRE

    Samarakoon, S. M. S.; Chandola, H. M.; Ravishankar, B.

    2011-01-01

    Aging is unavoidable and natural phenomenon of life. Modern gerontologists are realizing the fact that aging is a disease, which Ayurveda had accepted as natural disease since long. Rate of aging is determined by one's biological, social, lifestyle, and psychological conditions and adversity of which leads to accelerated form of aging (Akalaja jara or premature aging). The aim of this study is to identify potential factors that may accelerate aging in the context of dietry factors, lifestyle ...

  11. Youngest radiocarbon age for Jefferson's ground sloth, Megalonyx jeffersonii (Xenarthra, Megalonychidae)

    Science.gov (United States)

    Gregory McDonald, H.; Stafford, Thomas W.; Gnidovec, Dale M.

    2015-03-01

    A partial skeleton of the extinct ground sloth, Megalonyx jeffersonii, recovered from a farm near Millersburg, Ohio in 1890, was radiocarbon dated for the first time. The ungual dated is part of a skeleton mounted for exhibit at the Orton Geological Museum at Ohio State University and was the first mounted skeleton of this animal. From its initial discovery the bones were treated with multiple organic compounds that had the potential to compromise the radiocarbon age and the specimen required special treatments in order to obtain a valid radiocarbon age. The 14C measurement on the ungual from this skeleton (11,235 ± 40 14C yr BP = 13,180-13,034 cal yr BP) is the youngest 14C age presently determined for M. jeffersonii.

  12. Montecrinanes A-C: Triterpenes with an Unprecedented Rearranged Tetracyclic Skeleton from Celastrus vulcanicola. Insights into Triterpenoid Biosynthesis Based on DFT Calculations.

    Science.gov (United States)

    Purino, Martín; Ardiles, Alejandro E; Callies, Oliver; Jiménez, Ignacio A; Bazzocchi, Isabel L

    2016-05-23

    Three new triterpenoids with an unprecedented 6/6/6/6-fused tetracyclic carbon skeleton, montecrinanes A-C (1-3), were isolated from the root bark of Celastrus vulcanicola, along with known D:B-friedobaccharanes (4-6), and lupane-type triterpenes (7-12). The stereostructures of the new metabolites were elucidated based on spectroscopic (1D and 2D NMR) and spectrometric (HR-EIMS and HR-ESIMS) techniques. Their absolute configurations were determined by both NMR spectroscopy, with (R)-(-)-α-methoxyphenylacetic acid as a chiral derivatizing agent, and biogenetic considerations. Biogenetic pathways for montecrinane and D:B-friedobaccharane skeletons were proposed and studied by DFT methods. The theoretical results support the energetic feasibility of the putative biogenetic pathways, in which the 1,2-methyl shift from the secondary baccharenyl cation represents a novel and key reaction step for a new montecrinane skeleton. PMID:27106132

  13. Sports-Related Eye Injuries by Age

    Science.gov (United States)

    Sports-Related Eye Injuries by Age Activity Estimated Injuries* Ages 0–14 Ages 15+ Basketball 5,237 ... Exercise, Weightlifting) 1,697 401 1,297 Racquet Sports 1,241 233 1,008 Ball Sports, Unspecified ...

  14. A Faster Algorithm for Computing Straight Skeletons

    KAUST Repository

    Cheng, Siu-Wing

    2014-09-01

    We present a new algorithm for computing the straight skeleton of a polygon. For a polygon with n vertices, among which r are reflex vertices, we give a deterministic algorithm that reduces the straight skeleton computation to a motorcycle graph computation in O(n (logn)logr) time. It improves on the previously best known algorithm for this reduction, which is randomized, and runs in expected O(n√h+1log2n) time for a polygon with h holes. Using known motorcycle graph algorithms, our result yields improved time bounds for computing straight skeletons. In particular, we can compute the straight skeleton of a non-degenerate polygon in O(n (logn) logr + r 4/3 + ε ) time for any ε > 0. On degenerate input, our time bound increases to O(n (logn) logr + r 17/11 + ε ).

  15. A Faster Algorithm for Computing Straight Skeletons

    KAUST Repository

    Mencel, Liam A.

    2014-05-06

    We present a new algorithm for computing the straight skeleton of a polygon. For a polygon with n vertices, among which r are reflex vertices, we give a deterministic algorithm that reduces the straight skeleton computation to a motorcycle graph computation in O(n (log n) log r) time. It improves on the previously best known algorithm for this reduction, which is randomised, and runs in expected O(n √(h+1) log² n) time for a polygon with h holes. Using known motorcycle graph algorithms, our result yields improved time bounds for computing straight skeletons. In particular, we can compute the straight skeleton of a non-degenerate polygon in O(n (log n) log r + r^(4/3 + ε)) time for any ε > 0. On degenerate input, our time bound increases to O(n (log n) log r + r^(17/11 + ε))

  16. Utility of telomere length measurements for age determination of humpback whales

    Directory of Open Access Journals (Sweden)

    Morten Tange Olsen

    2014-12-01

    Full Text Available This study examines the applicability of telomere length measurements by quantitative PCR as a tool for minimally invasive age determination of free-ranging cetaceans. We analysed telomere length in skin samples from 28 North Atlantic humpback whales (Megaptera novaeangliae, ranging from 0 to 26 years of age. The results suggested a significant correlation between telomere length and age in humpback whales. However, telomere length was highly variable among individuals of similar age, suggesting that telomere length measured by quantitative PCR is an imprecise determinant of age in humpback whales. The observed variation in individual telomere length was found to be a function of both experimental and biological variability, with the latter perhaps reflecting patterns of inheritance, resource allocation trade-offs, and stochasticity of the marine environment.

  17. A Practical Introduction to Skeletons for the Plant Sciences

    Directory of Open Access Journals (Sweden)

    Alexander Bucksch

    2014-08-01

    Full Text Available Before the availability of digital photography resulting from the invention of charged couple devices in 1969, the measurement of plant architecture was a manual process either on the plant itself or on traditional photographs. The introduction of cheap digital imaging devices for the consumer market enabled the wide use of digital images to capture the shape of plant networks such as roots, tree crowns, or leaf venation. Plant networks contain geometric traits that can establish links to genetic or physiological characteristics, support plant breeding efforts, drive evolutionary studies, or serve as input to plant growth simulations. Typically, traits are encoded in shape descriptors that are computed from imaging data. Skeletons are one class of shape descriptors that are used to describe the hierarchies and extent of branching and looping plant networks. While the mathematical understanding of skeletons is well developed, their application within the plant sciences remains challenging because the quality of the measurement depends partly on the interpretation of the skeleton. This article is meant to bridge the skeletonization literature in the plant sciences and related technical fields by discussing best practices for deriving diameters and approximating branching hierarchies in a plant network.

  18. NON-SKELETON BUILDING OF MULTIPURPOSE DESTINATION

    Directory of Open Access Journals (Sweden)

    В.М. Першаков

    2012-10-01

    Full Text Available  The non-skeleton structure of multipurpose destination is developed from typical reinforce-concrete slabs and intended for building of objects of agroindustrial complex. Fixed building is under the test loadings. After researches was established, that a construction has sufficient bearing capacity. Non-skeleton building is urgent for storage of agricultural production and storage of eguipment, placing of markets and sport complexes.

  19. Use of coral skeleton as environmental archives: The biological basis

    International Nuclear Information System (INIS)

    Full text: 'There has never been any doubt that corals write valuable information into their skeletons it is their language that has remained blurry and ambiguous'. Paleoceanographers derive information about past environmental conditions from stable isotopes and other tracer records held with geological structures. The skeletons of hermatypic corals are particularly useful for high-resolution studies of tropical paleoceanic environments as they provide an unaltered record of the chemical and physical conditions that existed in the seawater when they were formed. However, these structures do not result from pure chemical CaCO3 precipitation but from highly- regulated biological activities of living organisms. Indeed, trace elements and isotopes were shown to vary widely between and within species or to correlate well with coral growth or extension rates. It was therefore suggested that environmental factors are not completely controlling isotope and trace element signatures in coral skeletons but that biological factors were also important. Furthermore, most of reefbuilding corals harbor photosynthetic symbionts which stimulate by an unknown mechanism coral calcification, a process called light-enhanced calcification. Consequently, one must consider the effects of these biological activities on the distribution and fractionation of tracers to make correct inferences on climate at the time of skeleton formation. It is, therefore, necessary to understand the physiological mechanisms which control both biomineral formation and carbon supply to the photosynthetic symbiont, called 'vital effects'. This paper will present an up-to-date review of the biological control of the biomineralization process in corals which will allow an optimization for the use of coral skeletons as environmental archives. By using the branched scleractinian coral, Stylophora pistillata as a model organism, we have shown that coral skeleton formation results from two biological processes

  20. Nuclear physics techniques for determination of rocks age

    International Nuclear Information System (INIS)

    The low background nuclear physics techniques were used for measure age geologic samples of micas (biotite, lepidolite, muscovite, phlogopite) by means of detection a gamma radiation from radioisotopes. The nuclear reactions 87Sr(gamma,gamma)87mSr, 87Rb(gamma,n)86Rb and 85Rb(gamma,n)84Rb was used. Application of a braking radiation of the powerful accelerator of electrons has allowed simultaneously to measure an element composition of samples

  1. Marine reservoir corrections for bowhead whale radiocarbon age determinations

    International Nuclear Information System (INIS)

    Twenty-two pairs of radiocarbon dates on driftwood and bowhead whale (Balaena mysticetus) bones from raised beaches, dates on whale bone and terrestrial plant detritus from a stratigraphic section, and 25 additional dates on whale bones from the lowest (≤ 1 ka BP) raised beaches in the eastern Canadian Arctic suggest that a marine reservoir correction of about -200 years is appropriate for normalized age determinations on bone collagen from the bowhead whale in this region. This is less than the correction (-400 years) normally applied to carbonate shells of marine molluscs from this region. The carbon in bowhead collagen appears to be derived from the whales' zooplankton food rather than from marine bicarbonate. (author). 39 refs., 1 tab., 3 figs

  2. Lifestyle and dietary factors determine age at natural menopause.

    Science.gov (United States)

    Sapre, Shilpa; Thakur, Ratna

    2014-01-01

    A literature search was done using PubMed. The age at natural menopause (ANM) depends on various factors like genetic, environmental, socioeconomic, reproductive, dietary, and lifestyle of which some like nulliparity, vegetarian diet, smoking, high fat intake, cholesterol, and caffeine accelerates; while others like parity, prior use of oral contraceptive pills, and Japanese ethnicity delays the ANM. ANM is an important risk factor for long-term morbidity and mortality; and hence, the need to identify the modifiable risk factors like diet and lifestyle changes. Delayed menopause is associated with increased risk of endometrial and breast cancer, while early ANM enhances the risk for cardiovascular diseases and osteoporosis. The correlation between diet and ANM has not been extensively studied; however, whatever studies have been done till now point towards role of high intake of total calories, fruits, and proteins in delaying the ANM, while high polyunsaturated fat intake accelerates it. The role of dietary soy, total fat, saturated fat, red meat, and dietary fiber in determining the ANM has been controversial and needs further studies to substantiate it. The lifestyle factors like current smoking and vigorous exercise have been significantly associated with early menopause, while moderate alcohol consumption delays the ANM. Large prospective studies are needed to study the association of ANM and other modifiable factors like passive smoking fish consumption, soy, and various types of tea. The knowledge of modifiable determinants of ANM can help in setting up menopausal clinics and initiating health programs specially in developing countries. PMID:24672198

  3. Dentition and age determination of the Warthog Phacochoerus aethiopicus in Zululand, South Africa

    Directory of Open Access Journals (Sweden)

    D.R Mason

    1984-12-01

    Full Text Available Age-specific stages of tooth replacement, eruption and attrition are described for warthogs shot during population control in Zululand. Patterns of tooth replacement and eruption allowed reasonably accurate age determination up to 24 months, whereafter 2-3 year old warthogs could generally be distinguished from older individuals by the relative growth of their third molars. Although stages of wear and loss of the teeth, especially the three molars, were associated with broad age classes, age of adult warthogs may be determined more precisely by counting cementum annuli in sectioned incisor teeth. However, cementum annuli were insufficiently distinctive to permit age estimation in approximately 33 of sections, reflecting particularly variation in intensity and clarity of staining and splitting and merging of rest lines. The use of eye lens dry mass and tusk length: snout width ratios as indices of age was also evaluated. Eye lens dry mass became increasingly unreliable for predicting age beyond 24 months. Considering males and females separately, tusk length: snout width ratios for yearling, 2-3 year old and 3-4 year old warthogs were reasonably distinctive, but subsequent overlap was apparently unfavourable for reliable differentiation of year classes among older warthogs. Body size and tusk * development criteria for distinguishing between three age classes ofwarthogs in the field are presented.

  4. Ligubenzocycloheptanone A, a Novel Tricyclic Butenolide with a 6/7/5 Skeleton from Ligusticum chuanxiong

    Science.gov (United States)

    Han, Bing; Zhang, Xu; Feng, Zi-Ming; Jiang, Jian-Shuang; Li, Li; Yang, Ya-Nan; Zhang, Pei-Cheng

    2016-01-01

    Ligubenzocycloheptanone A (1), a novel tricyclic butenolide with a 6/7/5-membered ring skeleton, was isolated from the rhizome of Ligusticum chuanxiong. Its unusual structure was determined using UV, IR, HRESIMS, 1D and 2D NMR data, X-ray diffraction crystallography and by the comparison of experimental and calculated electronic circular dichroism (ECD) spectra. 1 possessed a benzocycloheptanone core featuring butyrolactone, which is rarely observed in nature. A possible biosynthetic pathway was proposed. Ligubenzocycloheptanone A showed strong radical scavenging activity with an IC50 value of 2.3 μM. PMID:27461841

  5. Radionuclide distribution dynamics in skeletons of beagles fed 90Sr: Correlation with injected 226Ra and 239Pu

    International Nuclear Information System (INIS)

    Data for the bone-by-bone redistribution of 90Sr in the beagle skeleton are reported for a period of 4000 d following a midgestation-to-540-d-exposure by ingestion. The partitioned clearance model (PCM) that was originally developed to describe bone-by-bone radionuclide redistribution of 226Ra after eight semimonthly injections at ages 435-535 d has been fitted to the 90Sr data. The parameter estimates for the PCM that describe the distribution and clearance of 226Ra after deposition on surfaces following injection and analogous parameter estimates for 90Sr after uniform deposition in the skeleton as a function of Ca mass are given. Fractional compact bone masses per bone group (mi,COM) are also predicted by the model and compared to measured values; a high degree of correlation (r = 0.84) is found. Bone groups for which the agreement between the model and experimental values of mi,COM was poor had tissue-to-calcium weight ratios about 1.5 times those for bones that agreed well. Metabolically defined surface in PCM is initial activity fraction per Ca fraction in a given skeletal component for intravenously injected alkaline earth (Sae) radionuclides; comparisons are made to similarly defined surface (Sact) values from 239Pu injection studies. The patterns of Sae and Sact distribution throughout the skeleton are similar

  6. The Local Theory of the Cosmic Skeleton

    CERN Document Server

    Pogosyan, D; Gay, C; Prunet, S; Cardoso, J F; Sousbie, T; Colombi, S

    2008-01-01

    The local theory of the critical lines of 2D and 3D Gaussian fields that underline the cosmic structures is presented. In the context of cosmological matter distribution the subset of critical lines of the 3D density field serves to delineate the skeleton of the observed filamentary structure at large scales. A stiff approximation used to quantitatively describe the filamentary skeleton shows that the flux of the skeleton lines is related to the average Gaussian curvature of the 1D (2D) sections of the field, much in the same way as the density of the peaks. The distribution of the length of the critical lines with threshold is analyzed in detail, while the extended descriptors of the skeleton - its curvature and its singular points, are introduced and briefly described. Theoretical predictions are compared to measurements of the skeleton in realizations of Gaussian random fields in 2D and 3D. It is found that the stiff approximation predicts accurately the shape of the differential length, allows for analyti...

  7. Multidimensional $\\beta$-skeletons in $L_1$ and $L_{\\infty}$ metric

    OpenAIRE

    Kowaluk, Mirosław; Majewska, Gabriela

    2014-01-01

    The $\\beta$-skeleton $\\{G_{\\beta}(V)\\}$ for a point set V is a family of geometric graphs, defined by the notion of neighborhoods parameterized by real number $0 < \\beta < \\infty$. By using the distance-based version definition of $\\beta$-skeletons we study those graphs for a set of points in $\\mathbb{R}^d$ space with $l_1$ and $l_{\\infty}$ metrics. We present algorithms for the entire spectrum of $\\beta$ values and we discuss properties of lens-based and circle-based $\\beta$-skeletons in tho...

  8. Work characteristics and determinants of job satisfaction in four age groups: university employees’ point of view

    OpenAIRE

    Bos, Judith T; Donders, Nathalie C. G. M.; Bouwman-Brouwer, Karin M.; Van der Gulden, Joost W. J.

    2009-01-01

    Purpose To investigate (a) differences in work characteristics and (b) determinants of job satisfaction among employees in different age groups. Methods A cross-sectional questionnaire was filled in by 1,112 university employees, classified into four age groups. (a) Work characteristics were analysed with ANOVA while adjusting for sex and job classification. (b) Job satisfaction was regressed against job demands and job resources adapted from the Job Demands-Resources model. Results Statistic...

  9. Effects Of Aging On Embrittlement By Hydrogen

    Science.gov (United States)

    Lassila, D. H.; Birnbaum, H. K.

    1989-01-01

    Report discusses study of grain-boundary fracture of hydrogen-charged nickel under conditions in which hydrogen is immobile. Thermally-charged nickel specimens aged at several temperatures for various periods of time to allow hydrogen to diffuse. Specimens then quenched and tested in liquid nitrogen (at temperature of 77 K) so distribution of hydrogen produced by aging maintained.

  10. Analytical method for the K/Ca age determination of geological samples

    International Nuclear Information System (INIS)

    An analytical procedure for the K/Ca age determination of geological samples is described, the relevant equations are developed and two alternative analytical methods are discussed according to their precision. An important precondition for the feasibility of the K/Ca method is the measurement of precise Ca isotope ratios. The ratio 40Ca/42Ca is used to determine the relative radiogenic 40Ca portion, whereas the 42Ca/44Ca ratio is taken as an internal standard. K and Ca in minerals are determined by flame atomic emission spectrometry with an internal lithium standard and by isotope dilution mass spectrometry, respectively. The contamination problem during the reprocessing of the samples is discussed. The results achieved by dating a langbeinite and a microcline sample by the K/Ca method agree well with those achieved by other age determination methods. The standard deviation of the K/Ca method in analyzing several feldspars ranges from 1.8-7.6%. (orig.)

  11. Age determination of fish from scales; method and application to fish cultural problems

    Science.gov (United States)

    Hile, Ralph

    1936-01-01

    THE SCIENCE of "scale reading", or determination of the age of fish from the examination of their scales, is less than 40 years old. Yet today the publications on the subject are to be numbered by the hundreds, and there is scarcely any phase of fish and fishery work that has not been benefited by this powerful tool for investigation. Fish culture is no exception to this rule. It is because of the increasing interest of fish culturists in scale reading and their numerous requests for information on the subject, that I have been asked to prepare a brief discussion of the method of age determination in fishes.

  12. Using colours to determine the stellar ages and metallicities of distant galaxies

    CERN Document Server

    Li, Zhongmu

    2013-01-01

    The determination of stellar populations of galaxies are important for studying the formation and evolution of galaxies, because all galaxies contain many stars and they evolve with galaxies. Spectra data are usually used to determine the stellar populations of nearby galaxies as they have the ability to disentangle the degeneracy between stellar age and metallicity. However, it is difficult to give similar studies to distant (e.g., $z >$ 0.3) galaxies because of the lack of reliable spectra data. This is actually limited by current observational equipments and methods. In fact, the information of the stellar ages and metallicities of distant galaxies are crucial for solving the problem of galaxy formation and evolution. Colours can give us some information of the stellar populations of distant galaxies. In the paper, I introduce our works about using colours to estimate the ages and metallicities of the stellar populations of galaxies. Some potential colours for studying stellar-population parameters (age an...

  13. 29 CFR Appendix D to Part 4044 - Tables Used To Determine Expected Retirement Age

    Science.gov (United States)

    2010-07-01

    ... 29 Labor 9 2010-07-01 2010-07-01 false Tables Used To Determine Expected Retirement Age D Appendix... 4044—Tables Used To Determine Expected Retirement Age TABLE I-10—Selection of Retirement Rate Category... Participant's earliest retirement age at valuation date. Unreduced retirement age 60 61 62 63 64 65 66 67...

  14. Social relations as determinant of onset of disability in aging

    DEFF Research Database (Denmark)

    Avlund, Kirsten; Holstein, Bjørn E; Due, Pernille

    2013-01-01

    The purpose of the study was to analyze whether social relations are related to onset of disability among old people at 1.5 year follow-up and whether these relations vary by age and gender. The study is based on baseline and 1.5 year follow-up data on 1396 older non-disabled adults. Social...... relations were measured by questions about diversity in social relations, social participation, satisfaction with social relations and instrumental social support. Onset of disability was described as developing need of help in at least one of six mobility activities. The results showed that a large...... network of social relations provides protection against disability by reducing risk of developing disability....

  15. Social relations as determinant of onset of disability in aging

    DEFF Research Database (Denmark)

    Avlund, Kirsten; Lund, Rikke; Holstein, Bjørn E;

    2003-01-01

    The purpose of the study was to analyze whether social relations are related to onset of disability among old people at 1.5 year follow-up and whether these relations vary by age and gender. The study is based on baseline and 1.5 year follow-up data on 1396 older non-disabled adults. Social...... relations were measured by questions about diversity in social relations, social participation, satisfaction with social relations and instrumental social support. Onset of disability was described as developing need of help in at least one of six mobility activities. The results showed that a large...... network of social relations provides protection against disability by reducing risk of developing disability....

  16. Nongenetic Determinants of Age at Menarche: A Systematic Review

    Directory of Open Access Journals (Sweden)

    Anna Yermachenko

    2014-01-01

    Full Text Available Background. The acceleration of pubertal development is an important medical and social problem, as it may result in increased morbidity and mortality in later life. This systematic review summarizes relevant data about nongenetic factors, which contribute to age at menarche (AAM, and suggests those which may be the most important. Methods. The available literature from 1980 till July 2013 was searched using PubMed and Google Scholar databases. Finally, 154 papers were selected for the analysis. Results. Environmental factors, which may affect AAM, vary in populations of different ethnicity. The prenatal, infancy, and early childhood periods are the most susceptible to these factors. Body weight, high animal protein intake, family stressors (e.g., single parenting, and physical activity seem to influence AAM in most populations. Conclusions. The data about influence of nongenetic factors on AAM are still inconsistent. The factors affecting prenatal and early childhood growth seem to have a larger effect on further sexual maturation. Further studies are needed in order to validate the association between other environmental determinants and AAM in different ethnical groups.

  17. Correlating the end-Triassic mass extinction and basalt volcanism of the Central Atlantic Magmatic Province at the 100,000-year level by high-precision U-Pb age determinations

    Science.gov (United States)

    Schoene, Blair; Guex, Jean; Bartolini, Annachiara; Schaltegger, Urs; Blackburn, Terrence J.

    2010-05-01

    The end-Triassic mass extinction is one of the five largest extinctions in Earth history, though considerable uncertainty remains in terms of its duration, causes and effects. Many workers suggest that the extinction was related directly or indirectly to adverse climate following the onset of the Central Atlantic Magmatic Province (CAMP), which erupted > 2.5x106 km3 of basalt in less than 1 Ma. However, there remains a need for precise and accurate geochronology to correlate the onset of CAMP volcanism, recorded uniquely in terrestrial sections, with the well-documented marine extinction event. We provide new chemical abrasion ID-TIMS U-Pb age determinations on ash bed and basaltic zircons using the well-calibrated EARTHTIME 202Pb-205Pb-233U-235U tracer solution, yielding data that are up to 70% more precise compared to single-Pb/single-U tracers. We show that the Triassic-Jurassic boundary (TJB) and end-Triassic biological crisis from two independent marine stratigraphic sections in northern Peru and in Nevada (USA) correlate with the onset of terrestrial flood volcanism in the Central Atlantic Magmatic Province (CAMP) to <150 ka. Ash bed samples reveal complicated U-Pb systematics, showing ranges in 206Pb/238U zircon dates of up to 2 Ma, representing a range of growth histories prior to eruption. Therefore, we use the youngest single closed-system zircon to approximate the eruption date. Three volcanic ash beds from the Pucara basin, northern Peru, bracket the TJB to a 206Pb/238U age of 201.31 ± 0.18/0.31/0.43 Ma (internal uncertainties/ with tracer calibration uncertainty/ with decay constant uncertainties). The first discovered ash bed from the New York canyon, Nevada, 1.5 m above TJB requires a boundary age of less than 201.33 ± 0.13 Ma. We also provide data from two laboratories which yield a new 206Pb/238U zircon age of 201.28 ± 0.02/0.22/0.31 Ma for the North Mtn. basalt, the lowest CAMP basalt from the Fundy basin, Nova Scotia. This narrows the

  18. Alendronate increases BMD at appendicular and axial skeletons in patients with established osteoporosis

    Directory of Open Access Journals (Sweden)

    Au Szeki

    2007-05-01

    Full Text Available Abstract Background To identify high-risk patients and provide pharmacological treatment is one of the effective approaches in prevention of osteoporotic fractures. This study investigated the effect of 12-month Alendronate treatment on bone mineral density (BMD and bone turnover biochemical markers in postmenopausal women with one or more non-traumatic fractures, i.e. patients with established osteoporosis. Methods A total of 118 Hong Kong postmenopausal Chinese women aged 50 to 75 with low-energy fracture at distal radius (Colles' fracture were recruited for BMD measurement at lumbar spine and non-dominant hip using Dual-Energy X-ray Absorptiometry (DXA. 47 women with BMD T-score below -2 SD at either side were identified as patients with established osteoporosis and then randomized into Alendronate group (n = 22 and placebo control group (n = 25 for BMD measurement at spine and hip using DXA and distal radius of the non-fracture side by peripheral quantitative computed tomography (pQCT, and bone turnover markers, including bone forming alkaline phosphatase (BALP and bone resorbing urinary Deoxypyridinoline (DPD. All measurements were repeated at 6 and 12 months. Results Alendronate treatment significantly increased BMD, more in weight-bearing skeletons (5.1% at spine and 2.5% at hip than in non-weight bearing skeleton (0.9% at distal radius after 12 months treatment. Spine T-score was significant improved in Alendronate group (p Conclusion 12 months Alendronate treatment was effective to increase BMD at both axial and appendicular skeletons in postmenopausal women with established osteoporosis.

  19. Human skeleton proportions from monocular data

    Institute of Scientific and Technical Information of China (English)

    PENG En; LI Ling

    2006-01-01

    This paper introduces a novel method for estimating the skeleton proportions ofa human figure from monocular data.The proposed system will first automatically extract the key frames and recover the perspective camera model from the 2D data.The human skeleton proportions are then estimated from the key frames using the recovered camera model without posture reconstruction. The proposed method is tested to be simple, fast and produce satisfactory results for the input data. The human model with estimated proportions can be used in future research involving human body modeling or human motion reconstruction.

  20. Diagnosis of spondyloarthritis of the axial skeleton

    International Nuclear Information System (INIS)

    Conventional radiography is used as the first-line imaging test in evaluating the axial skeleton for manifestations of spondyloarthritis, which is a cover term for five entities: ankylosing spondylitis, psoriatric spondyloarthritis, reactive arthritis, enteropathic arthritis, and undifferentiated spondyloarthritis. However, as it often takes many years from the onset of clinical symptoms and the first appearance of radiographic changes, a cross-sectional imaging is warranted (CT and/or MRI) for early diagnosis. MRI sensitively detects early inflammatory stages of spondyloarthritis and can thus fill the gap by markedly reducing the interval between initial symptoms and diagnosis. The aim of this article is to show that all manifestations and forms of spondyloarthritis share the same pathogenetic inflammatory pattern, namely a mixture of bone destruction and bone proliferation: enthesis - enthesitis - enthesiophyte. An enthesis in the true sense is a fibrocartilaginous junction (uncalcified fibrocartilage - tidemark - calcified fibrocartilage) between a tendon, ligament, joint capsule, or fascia and bone. The sacroiliac joint is a special form, a so-called articular fibrocartilaginous enthesis. A wide range of images - including radiographs, CT scans, and MR images - will be presented to provide a comprehensive picture of the entheseal manifestations and inflammatory patterns of the sacroiliac joints, vertebral endplates and ridges, facet joints, costovertebral junctions, and spinal ligaments in spondyloarthritis. (orig.)

  1. The Skeleton of the Milky Way

    CERN Document Server

    Zucker, Catherine; Goodman, Alyssa

    2015-01-01

    Recently, Goodman et al. (2014) argued that the very long, very thin infrared dark cloud "Nessie" lies directly in the Galactic mid-plane and runs along the Scutum-Centaurus arm in position-position-velocity ($p-p-v$) space as traced by lower density $\\rm {CO}$ and higher density ${\\rm NH}_3$ gas. Nessie was presented as the first "bone" of the Milky Way, an extraordinarily long, thin, high-contrast filament that can be used to map our Galaxy's "skeleton." Here, we present evidence for additional bones in the Milky Way Galaxy, arguing that Nessie is not a curiosity but one of several filaments that could potentially trace Galactic structure. Our ten bone candidates are all long, filamentary, mid-infrared extinction features which lie parallel to, and no more than 20 pc from, the physical Galactic mid-plane. We use $\\rm {CO}$, ${\\rm N}_2{\\rm H}^+$, $\\rm {HCO}^+$, and ${\\rm NH}_3$ radial velocity data to establish the three-dimensional location of the candidates in ${\\it p-p-v}$ space. Of the ten candidates, si...

  2. Axon Membrane Skeleton Structure is Optimized for Coordinated Sodium Propagation

    CERN Document Server

    Zhang, Yihao; Li, He; Tzingounis, Anastasios V; Lykotrafitis, George

    2016-01-01

    Axons transmit action potentials with high fidelity and minimal jitter. This unique capability is likely the result of the spatiotemporal arrangement of sodium channels along the axon. Super-resolution microscopy recently revealed that the axon membrane skeleton is structured as a series of actin rings connected by spectrin filaments that are held under entropic tension. Sodium channels also exhibit a periodic distribution pattern, as they bind to ankyrin G, which associates with spectrin. Here, we elucidate the relationship between the axon membrane skeleton structure and the function of the axon. By combining cytoskeletal dynamics and continuum diffusion modeling, we show that spectrin filaments under tension minimize the thermal fluctuations of sodium channels and prevent overlap of neighboring channel trajectories. Importantly, this axon skeletal arrangement allows for a highly reproducible band-like activation of sodium channels leading to coordinated sodium propagation along the axon.

  3. Determining the prevalence of obesity in the 6-11 age group active and sedentary children

    OpenAIRE

    Yücesir, İlker; Bektaş, İlknur

    2015-01-01

    AbstractOperating one of the four primary schools in the state, including three special, 6-11 girls between the ages of moving or still being carried out to determine the effect of high-frequency weightedand obese. Mean age =8.29±1.50, which research was con­ducted on 596 girls. Children’s height and weight were measured in this study, body mass index was calculated by comparing the values inage-appropriateper centile values, low, normal, high weighted and obese children were determined. Pare...

  4. Automated Determination of Bone Age in a Modern Chinese Population

    OpenAIRE

    Zhang, Shao-yan; Liu, Gang; Ma, Chen-Guo; Han, Yi-San; Shen, Xun-Zhang; XU, RUI-LONG; Thodberg, Hans Henrik

    2013-01-01

    Rationale and Objective. Large studies have previously been performed to set up a Chinese bone age reference, but it has been difficult to compare the maturation of Chinese children with populations elsewhere due to the potential variability between raters in different parts of the world. We re-analysed the radiographs from a large study of normal Chinese children using an automated bone age rating method to establish a Chinese bone age reference, and to compare the tempo of maturation in the...

  5. CodeSkelGen - A Program Skeleton Generator

    OpenAIRE

    Queirós, Ricardo

    2013-01-01

    Existent computer programming training environments help users to learn programming by solving problems from scratch. Nevertheless, initiating the resolution of a program can be frustrating and demotivating if the student does not know where and how to start. Skeleton programming facilitates a top-down design approach, where a partially functional system with complete high-level structures is available, so the student needs only to progressively complete or update the code to meet the r...

  6. Dynamic Hand Gesture Recognition Using the Skeleton of the Hand

    Directory of Open Access Journals (Sweden)

    Vasile Buzuloiu

    2005-08-01

    Full Text Available This paper discusses the use of the computer vision in the interpretation of human gestures. Hand gestures would be an intuitive and ideal way of exchanging information with other people in a virtual space, guiding some robots to perform certain tasks in a hostile environment, or interacting with computers. Hand gestures can be divided into two main categories: static gestures and dynamic gestures. In this paper, a novel dynamic hand gesture recognition technique is proposed. It is based on the 2D skeleton representation of the hand. For each gesture, the hand skeletons of each posture are superposed providing a single image which is the dynamic signature of the gesture. The recognition is performed by comparing this signature with the ones from a gesture alphabet, using Baddeley's distance as a measure of dissimilarities between model parameters.

  7. Dynamic Hand Gesture Recognition Using the Skeleton of the Hand

    Science.gov (United States)

    Ionescu, Bogdan; Coquin, Didier; Lambert, Patrick; Buzuloiu, Vasile

    2005-12-01

    This paper discusses the use of the computer vision in the interpretation of human gestures. Hand gestures would be an intuitive and ideal way of exchanging information with other people in a virtual space, guiding some robots to perform certain tasks in a hostile environment, or interacting with computers. Hand gestures can be divided into two main categories: static gestures and dynamic gestures. In this paper, a novel dynamic hand gesture recognition technique is proposed. It is based on the 2D skeleton representation of the hand. For each gesture, the hand skeletons of each posture are superposed providing a single image which is the dynamic signature of the gesture. The recognition is performed by comparing this signature with the ones from a gesture alphabet, using Baddeley's distance as a measure of dissimilarities between model parameters.

  8. Estimating age in black South African children.

    Science.gov (United States)

    Uys, A; Fabris-Rotelli, I; Bernitz, H

    2014-03-01

    Forensic dentists are frequently required to determine the age at death of unidentified skeletons, or to age live individuals who have no record/documentation of their chronological age. In order to be of the greatest value, the method used should have the lowest possible standard deviation and be validated for the individual's specific population group. The method most frequently used in Forensic Dentistry for the estimation of age in children, was described by Demirjian et al. The maturity standards determined were based on samples of French Canadian origin and it has been recommended by several authors that correction factors be incorporated when applying this method to different population groups. The current research was carried out on a sample of 838 black South African children. A new model for age estimation in the said population was developed, to accurately determine the chronological age from dental development. A sample of 604 black South African children was used to test the validity of the method described by Demirjian. PMID:24974518

  9. Job Satisfaction, Work Environment, and Successful Aging: Determinants to Remain in Older Acute Care Nurses

    OpenAIRE

    Wargo-Sugleris, Michele

    2015-01-01

    Michele Wargo-SuglerisDoctor of Philosophy in NursingUniversity of California, Los Angeles, 2013Professor Emeritus Linda R. Phillips, ChairThis study investigated the determinants of job satisfaction, work environment, and successful aging in association with retire among older registered nurses (RNs). In addition, this study was designed to further understand what motivates nurses to remain employed in their current positions by investigating the relationship among these determinants and th...

  10. Utility of telomere length measurements for age determination of humpback whales

    DEFF Research Database (Denmark)

    Olsen, Morten Tange

    2014-01-01

    This study examines the applicability of telomere length measurements by quantitative PCR as a tool for minimally invasive age determination of free-ranging cetaceans. We analysed telomere length in skin samples from 28 North Atlantic humpback whales (Megaptera novaeangliae), ranging from 0 to 26...

  11. Osteoarthritis. Radiological aspects in the appendicular skeleton

    International Nuclear Information System (INIS)

    The osteoarthritis is a degenerative and inflammatory disease that affects all articular structures, especially cartilage and intervertebral disc, which conduce to progressive impairment of the joint. In this paper it Is showed the most significative cardiology findings of osteoarthritis in the appendicular skeleton that are fundamental for the diagnosis of this frequent pathology

  12. Spinal deformity in aged zebrafish is accompanied by degenerative changes to their vertebrae that resemble osteoarthritis.

    Directory of Open Access Journals (Sweden)

    Anthony J Hayes

    Full Text Available Age-related degenerative changes within the vertebral column are a significant cause of morbidity with considerable socio-economic impact worldwide. An improved understanding of these changes through the development of experimental models may lead to improvements in existing clinical treatment options. The zebrafish is a well-established model for the study of skeletogenesis with significant potential in gerontological research. With advancing age, zebrafish frequently develop gross deformities of their vertebral column, previously ascribed to reduced trunk muscle tone. In this study, we assess degenerative changes specifically within the bone and cartilage of the vertebral column of zebrafish at 1, 2 and 3-years of age. We show increased frequency and severity of spinal deformities/curvatures with age. Underlying the most severe phenotypes are partial or complete vertebral dislocations and focal thickening of the vertebral bone at the joint margins. MicroCT examination demonstrates small defects, fractures and morphological evidence suggestive of bone erosion and remodeling (i.e. osteophytes within the vertebrae during aging, but no significant change in bone density. Light and electron microscopic examination reveal striking age-related changes in cell morphology, suggestive of chondroptosis, and tissue remodelling of the vertebral cartilage, particularly within the pericellular micro-environment. Glycosaminoglycan analysis of the vertebral column by HPLC demonstrates a consistent, age-related increase in the yield of total chondroitin sulfate disaccharide, but no change in sulfation pattern, supported by immunohistochemical analysis. Immunohistochemistry strongly identifies all three chondroitin/dermatan sulphate isoforms (C-0-S, C-4-S/DS and C-6-S within the vertebral cartilage, particularly within the pericellular micro-environment. In contrast, keratan sulfate immunolocalises specifically with the notochordal tissue of the intervertebral

  13. Ecological determinants of mean family age of angiosperm trees in forest communities in China

    Science.gov (United States)

    Qian, Hong; Chen, Shengbin

    2016-01-01

    Species assemblage in a local community is determined by the interplay of evolutionary and ecological processes. The Tropical Niche Conservatism hypothesis proposes mechanisms underlying patterns of biodiversity in biological communities along environmental gradients. This hypothesis predicts that, among other things, clades in areas with warm or wet environments are, on average, older than those in areas with cold or dry environments. Focusing on angiosperm trees in forests, this study tested the age-related prediction of the Tropical Niche Conservatism hypothesis. We related the mean family age of angiosperm trees in 57 local forests from across China with 23 current and paleo-environmental variables, which included all major temperature- and precipitation-related variables. Our study shows that the mean family age of angiosperm trees in local forests was positively correlated with temperature and precipitation. This finding is consistent with the age-related prediction of the Tropical Niche Conservatism hypothesis. Approximately 85% of the variance in the mean family age of angiosperm trees was explained by temperature-related variables, and 81% of the variance in the mean family age of angiosperm trees was explained by precipitation-related variables. Climatic conditions at the Last Glacial Maximum did not explain additional variation in mean family age after accounting for current environmental conditions. PMID:27354109

  14. OSL age determinations of Pleistocene fluvial deposits in Central Amazonia

    Directory of Open Access Journals (Sweden)

    Emílio A.A. Soares

    2010-09-01

    Full Text Available Absolute dating methods have been used in chronological studies of geological processes and sedimentary units of Quaternary age in Central Amazonia, Brazil. Although radiocarbon dating has been very useful in archaeological research and soil studies, the temporal interval of this method is inefficient in evaluating the sedimentation aspects and geological events from the beginning of the Quaternary in the Amazon basin. The use of crystal luminescence dating has been one of the most promising tool for determining the absolute dating of Quaternary deposits in the Amazonian region. Optically stimulated luminescence (OSL dating, following the MAR and SAR protocols, in a tectonic-sedimentary study of Quaternary fluvial deposits in the confluence area of the Negro and Solimões rivers, indicated ages from 1.3 (Holocene to about 67.4 kyears (Late Pleistocene for these sediments. Low radioactive isotope concentrations were found about 2ppm for 235U and 238U; 5ppm for 232Th; and the 40K concentrations were almost zero. A comparison was made between MAR and SAR protocols taking into account the fluvial depositional process.Métodos de datação absoluta têm sido usados em estudos cronológicos de processos geológicos e unidades sedimentares de idade quaternária na Amazônia Central, Brasil. Embora as datações pelo 14C tenham sido muito úteis na pesquisa arqueológica e estudos de solos, o intervalo de tempo abrangido por este método é ineficiente para avaliar aspectos da sedimentação e eventos geológicos do início do Quaternário na bacia Amazônica. O uso da datação por luminescência de cristais tem sido uma das ferramentas mais promissoras para a determinação da idade absoluta de depósitos quaternários na região amazônica. A datação por luminescência opticamente estimulada (LOE, seguindo os protocolos MAR e SAR, em um estudo tectono-sedimentar de depósitos aluviais quaternários da área de confluência dos rios Negro e Solim

  15. Skeleton-Sectional Structural Analysis for 3D Printing

    Institute of Scientific and Technical Information of China (English)

    Wen-Peng Xu; Wei Li; Li-Gang Liu

    2016-01-01

    3D printing has become popular and has been widely used in various applications in recent years. More and more home users have motivation to design their own models and then fabricate them using 3D printers. However, the printed objects may have some structural or stress defects as the users may be lack of knowledge on stress analysis on 3D models. In this paper, we present an approach to help users analyze a model’s structural strength while designing its shape. We adopt sectional structural analysis instead of conventional FEM (Finite Element Method) analysis which is computationally expensive. Based on sectional structural analysis, our approach imports skeletons to assist in integrating mesh designing, strength computing and mesh correction well. Skeletons can also guide sections building and load calculation for analysis. For weak regions with high stress over a threshold value in the model from analysis result, our system corrects them by scaling the corresponding bones of skeleton so as to make these regions stiff enough. A number of experiments have demonstrated the applicability and practicability of our approach.

  16. Relative age determination of Rattus tiomanicus using allometric measurements

    OpenAIRE

    Verwilghen, Aude; Rabillard, Marie-Agnes; Chaval, Yannick; Rieffel, Dominique; Sinaga, Martua Hasiholan; Naim, Mohd; Caliman, Jean-Pierre; Giraudoux, Patrick; Raoul, Francis

    2015-01-01

    For sustainable oil palm production, barn owl (Tyto alba) predation should be enhanced and monitored to better understand its impact on rodent population dynamics, notably for selective predation based on age or size. Our aim was to assess the best combination of osteometric variables that predict eye lens weight and thus the relative age of an individual Rattus tiomanicus based on pellet remains. We captured 161 individuals in an oil palm plantation in Indonesia and measured 15 osteometric v...

  17. Computer system for determination of cultural relic's age

    International Nuclear Information System (INIS)

    The computer is described in which thermoluminescent dosimeter is used for measuring ancient porcelain's age. The calculating formula of cultural relic's age, the working principle of the computer interface circuit and the design strategy of software are given. This system has been put into practical use for two years. The performance is stable and the operation is convenient. The calculation speed is raised as well as the calculation precision is guaranteed. All kinds of original data can be stored

  18. Marble Ageing Characterization by Acoustic Waves

    Science.gov (United States)

    Boudani, Mohamed El; Wilkie-Chancellier, Nicolas; Martinez, Loïc; Hébert, Ronan; Rolland, Olivier; Forst, Sébastien; Vergès-Belmin, Véronique; Serfaty, Stéphane

    In cultural heritage, statue marble characterization by acoustic waves is a well-known non-destructive method. Such investigations through the statues by time of flight method (TOF) point out sound speeds decrease with ageing. However for outdoor stored statues as the ones in the gardens of Chateau de Versailles, ageing affects mainly the surface of the Carrara marble. The present paper proposes an experimental study of the marble acoustic properties variations during accelerated laboratory ageing. The surface degradation of the marble is reproduced in laboratory for 29 mm thick marble samples by using heating/cooling thermal cycles on one face of a marble plate. Acoustic waves are generated by 1 MHz central frequency contact transducers excited by a voltage pulse placed on both sides of the plate. During the ageing and by using ad hoc transducers, the marble samples are characterized in transmission, along their volume by shear, compressional TOF measurements and along their surface by Rayleigh waves measurements. For Rayleigh waves, both TOF by transducers and laser vibrometry methods are used to detect the Rayleigh wave. The transmission measurements point out a deep decrease of the waves speeds in conjunction with a dramatic decrease of the maximum frequency transmitted. The marble acts as a low pass filter whose characteristic frequency cut decreases with ageing. This pattern occurs also for the Rayleigh wave surface measurements. The speed change in conjunction with the bandwidth translation is shown to be correlated to the material de-structuration during ageing. With a similar behavior but reversed in time, the same king of phenomena have been observed trough sol-gel materials during their structuration from liquid to solid state (Martinez, L. et all (2004). "Chirp-Z analysis for sol-gel transition monitoring". Ultrasonics, 42(1), 507-510.). A model is proposed to interpret the acoustical measurements

  19. Enzalutamide Reduces the Bone Mass in the Axial But Not the Appendicular Skeleton in Male Mice.

    Science.gov (United States)

    Wu, Jianyao; Movérare-Skrtic, Sofia; Börjesson, Anna E; Lagerquist, Marie K; Sjögren, Klara; Windahl, Sara H; Koskela, Antti; Grahnemo, Louise; Islander, Ulrika; Wilhelmson, Anna S; Tivesten, Åsa; Tuukkanen, Juha; Ohlsson, Claes

    2016-02-01

    Testosterone is a crucial regulator of the skeleton, but the role of the androgen receptor (AR) for the maintenance of the adult male skeleton is unclear. In the present study, the role of the AR for bone metabolism and skeletal growth after sexual maturation was evaluated by means of the drug enzalutamide, which is a new AR antagonist used in the treatment of prostate cancer patients. Nine-week-old male mice were treated with 10, 30, or 100 mg/kg·d of enzalutamide for 21 days or were surgically castrated and were compared with vehicle-treated gonadal intact mice. Although orchidectomy reduced the cortical bone thickness and trabecular bone volume fraction in the appendicular skeleton, these parameters were unaffected by enzalutamide. In contrast, both enzalutamide and orchidectomy reduced the bone mass in the axial skeleton as demonstrated by a reduced lumbar spine areal bone mineral density (P < .001) and trabecular bone volume fraction in L5 vertebrae (P < .001) compared with vehicle-treated gonadal intact mice. A compression test of the L5 vertebrae revealed that the mechanical strength in the axial skeleton was significantly reduced by enzalutamide (maximal load at failure -15.3% ± 3.5%; P < .01). The effects of enzalutamide in the axial skeleton were associated with a high bone turnover. In conclusion, enzalutamide reduces the bone mass in the axial but not the appendicular skeleton in male mice after sexual maturation. We propose that the effect of testosterone on the axial skeleton in male mice is mainly mediated via the AR. PMID:26587782

  20. Lamprey type II collagen and Sox9 reveal an ancient origin of the vertebrate collagenous skeleton

    OpenAIRE

    Zhang, Guangjun; Miyamoto, Michael M.; Cohn, Martin J.

    2006-01-01

    Type II collagen is the major cartilage matrix protein in the jawed vertebrate skeleton. Lampreys and hagfishes, by contrast, are thought to have noncollagenous cartilage. This difference in skeletal structure has led to the hypothesis that the vertebrate common ancestor had a noncollagenous skeleton, with type II collagen becoming the predominant cartilage matrix protein after the divergence of jawless fish from the jawed vertebrates ≈500 million years ago. Here we report that lampreys have ...

  1. Skeleton based parallel programming: functional and parallel semantics in a single shot

    OpenAIRE

    Aldinucci, Marco; Danelutto, Marco

    2004-01-01

    Different skeleton based parallel programming systems have been developed in past years. The main goal of these programming environments is to provide programmers with handy, effective ways of writing parallel applications. In particular, skeleton based parallel programming environments automatically deal with most of the difficult, cumbersome programming problems that must be usually handled by programmers of parallel applications using traditional programming environments (e.g. environments...

  2. Optical, thermal, and structural characterization of the sclerotized skeleton of two antipatharian coral species

    International Nuclear Information System (INIS)

    Optical, thermal and structural characterization of the skeleton of two black coral species from the Western Caribbean Sea, Antipathes caribbeana and Antipathes pennacea is presented. Optical spectra in the UV-VIS region of both species have a strong absorbance around 350 nm. FTIR spectra in the mid-infrared spectra show the presence of a complex material similar to chitin for both species. X-ray diffraction analyses demanded a deproteinization treatment in order to observe the significant differences in the crystalline structure of chitin. The crystallite size in A. caribbeana is larger than in A. pennacea. Thermal characterization, performed by the photoacoustic technique, shows that in A. caribbeana skeleton the thermal conductivity is higher as compared with the thermal conductivity of the skeleton of A. pennacea. The difference in the thermal properties between coral species could be due to the array and packing of the chitin fiber skeletons

  3. Midlife Determinants Associated with Sedentary Behavior in Old Age

    DEFF Research Database (Denmark)

    van der Berg, Julianne D; Bosma, Hans; Caserotti, Paolo; Eiriksdottir, Gudny; Arnardottir, Nanna Yr; Martin, Kathryn R; Brychta, Robert J; Chen, Kong Y; Sveinsson, Thorarinn; Johannsson, Erlingur; Launer, Lenore J; Gudnason, Vilmundur; Jonsson, Palmi V; Stehouwer, Coen D A; Harris, Tamara B; Koster, Annemarie

    2014-01-01

    Sedentary behavior is associated with adverse health effects. To prevent sedentary behavior and limit health risks, insights into associated determinants are essential. Sedentary behavior should be viewed as a distinct health behavior, therefore its determinants should be independently identified...

  4. Isotopic age-determinations in Bergslagen, Sweden. 8

    International Nuclear Information System (INIS)

    Biotite Rb-Sr data from 1.70-1.65 Ga ol rocks of the Gothian Trans-Scandinavian Smaland-Vaermland Granitic Belt and from 1.90-1.84 Ga old rocks of the adjoining Svecokarelian Berglagen Region indicate complete Sveconorwegian resetting 0.90 Ga ago, but a K-Ar analysis of the same biotites and of coexisting hornblendes yields significantly older ages. Some biotites and hornblendes have exceptionally high apparent ages, much oldre than those of the host rocks, pointing to the presence of excess radiogenic argon. The other K-Ar mineral ages are intermediate between the age of the host rocks and the 0.90 Ga old Sveconorwegian resetting. The hornblendes and biotites with intermediate ages show a weak positive correlation between radiogenic argon content and whole-rock potassium content. It is concluded that there was only limited mobility of radiogenic argon during the Sveconorwegian event. Apperently, the physicochemical conditions during Sveconorwegian recrystallisation were suitable for complete resetting of the Rb-Sr biotite systems, whereas the behaviour of radiogenic argon in the biotites and hornblendes was complex, leading to anomalous K-Ar dates (author). 34 refs.; 4 figs.; 3 tabs

  5. Development and evaluation of an articulated registration algorithm for human skeleton registration

    International Nuclear Information System (INIS)

    Accurate registration over multiple scans is necessary to assess treatment response of bone diseases (e.g. metastatic bone lesions). This study aimed to develop and evaluate an articulated registration algorithm for the whole-body skeleton registration in human patients. In articulated registration, whole-body skeletons are registered by auto-segmenting into individual bones using atlas-based segmentation, and then rigidly aligning them. Sixteen patients (weight = 80–117 kg, height = 168–191 cm) with advanced prostate cancer underwent the pre- and mid-treatment PET/CT scans over a course of cancer therapy. Skeletons were extracted from the CT images by thresholding (HU>150). Skeletons were registered using the articulated, rigid, and deformable registration algorithms to account for position and postural variability between scans. The inter-observers agreement in the atlas creation, the agreement between the manually and atlas-based segmented bones, and the registration performances of all three registration algorithms were all assessed using the Dice similarity index—DSIobserved, DSIatlas, and DSIregister. Hausdorff distance (dHausdorff) of the registered skeletons was also used for registration evaluation. Nearly negligible inter-observers variability was found in the bone atlases creation as the DSIobserver was 96 ± 2%. Atlas-based and manual segmented bones were in excellent agreement with DSIatlas of 90 ± 3%. Articulated (DSIregsiter = 75 ± 2%, dHausdorff = 0.37 ± 0.08 cm) and deformable registration algorithms (DSIregister = 77 ± 3%, dHausdorff = 0.34 ± 0.08 cm) considerably outperformed the rigid registration algorithm (DSIregsiter = 59 ± 9%, dHausdorff = 0.69 ± 0.20 cm) in the skeleton registration as the rigid registration algorithm failed to capture the skeleton flexibility in the joints. Despite superior skeleton registration performance, deformable registration algorithm failed to preserve the local rigidity of bones as over

  6. Late Bronze Age hoard studied by PIXE

    International Nuclear Information System (INIS)

    The hoards of metallic objects belonging to the Late European Bronze Age can be interpreted differently depending on the type, number and composition of the artefacts. PIXE analysis has been performed in nine items from the Hoard of Freixanda in Portugal comprising four socket axes, a palstave axe, a ring, a chisel, a dagger, and a casting debris. Besides the composition of the main matrix elements, that is Cu and Sn, the amount of trace elements of interest like, As, Pb, Ni, and Ag has been determined using this ion beam technique. The high tin content alloy and the high purity of the metals from the Freixanda hoard are characteristic of the Portuguese and Spanish Late Bronze Age metallurgy, supporting the idea of a regional production.

  7. Age and sex determination of juvenile band-tailed pigeons

    Science.gov (United States)

    White, J.A.; Braun, C.E.

    1978-01-01

    Captive band-tailed pigeons (Columbafasciata) were studied to document progression of molts and plumages from juvenal to adult age. Immature pigeons began the post-juvenal molt at 35 days which continued up to 340 days. The only 3 plumage characters useful for identification and estimation of age were presence of juvenal lesser, middle, and greater secondary coverts, juvenal secondaries, and juvenal primaries. While juvenal primaries were still present, hatching dates could be estimated up to 252 days (N = 84). Secondary feather presence and molt stage could be used to identify juvenile pigeons for more than 340 days (N = 24). Using coloration of the crown and breast feathers, 96 percent of the immature pigeons examined (106 of 110) at 80 days of age were classified accurately as to sex.

  8. Quantifying yeast chronological life span by outgrowth of aged cells.

    Science.gov (United States)

    Murakami, Christopher; Kaeberlein, Matt

    2009-01-01

    The budding yeast Saccharomyces cerevisiae has proven to be an important model organism in the field of aging research. The replicative and chronological life spans are two established paradigms used to study aging in yeast. Replicative aging is defined as the number of daughter cells a single yeast mother cell produces before senescence; chronological aging is defined by the length of time cells can survive in a non-dividing, quiescence-like state. We have developed a high-throughput method for quantitative measurement of chronological life span. This method involves aging the cells in a defined medium under agitation and at constant temperature. At each age-point, a sub-population of cells is removed from the aging culture and inoculated into rich growth medium. A high-resolution growth curve is then obtained for this sub-population of aged cells using a Bioscreen C MBR machine. An algorithm is then applied to determine the relative proportion of viable cells in each sub-population based on the growth kinetics at each age-point. This method requires substantially less time and resources compared to other chronological lifespan assays while maintaining reproducibility and precision. The high-throughput nature of this assay should allow for large-scale genetic and chemical screens to identify novel longevity modifiers for further testing in more complex organisms. PMID:19421136

  9. Effect of single chemotherapeutic agents on the growing skeleton of the rat

    NARCIS (Netherlands)

    van Leeuwen, BL; Kamps, WA; Hartel, RM; Veth, RPH; Sluiter, WJ; Hoekstra, HJ

    2000-01-01

    Background: To establish the effect of chemotherapeutics on the growing skeleton, male Wistar rats were studied. Design: Between the ages of 4 and 13 weeks the rats were given i.v. doxorubicin 15 mg/m(2) body surface area (BSA), methotrexate 60 mg/m(2) BSA or cisplatin 7.5 mg/m(2) BSA. For each grou

  10. Direct Age Determination of a Subtropical Freshwater Crayfish (Redclaw, Cherax quadricarinatus) Using Ossicular Growth Marks.

    Science.gov (United States)

    Leland, Jesse C; Bucher, Daniel J; Coughran, Jason

    2015-01-01

    Recent studies have reported that crustacean age determination is possible. We applied a direct ageing method (i.e. transverse cross sectioning of gastric ossicles) to a subtropical freshwater crayfish (Cherax quadricarinatus) sourced from an aquaculture population. Growth mark periodicity and the potential for chronological depositions were investigated by staining C. quadricarinatus with calcein and examining their ossicles a year later. Pterocardiac ossicles were superior to other ageing structures (i.e. other ossicles and eyestalks) and produced repeatable between-reader counts (87% were corroborated and 13% varied by ±1). C. quadricarinatus size-at-age data (for an aquaculture population) was described by a von Bertalanffy growth equation (L∞ = 32 mm occipital carapace length; K = 0.64; t0 = -0.18; R2 = 0.81). Ossicular growth marks did not correspond to moult history. The calcein stain was retained over an annual cycle comprising multiple moults, demonstrating that pterocardiac ossicles retain chronological information. The maximum age (3+) corroborated other indirectly-obtained longevity estimates for C. quadricarinatus. Multiple lines of evidence indicate that the growth marks in C. quadricarinatus ossicles are probably deposited annually during winter. The ability to extract age information from subtropical decapods provides substantial opportunities for advancing fisheries and conservation research globally, but further research is needed to provide a definitive validation and elucidate the mechanism governing the accrual of ossicular growth marks. PMID:26309228

  11. Direct Age Determination of a Subtropical Freshwater Crayfish (Redclaw, Cherax quadricarinatus Using Ossicular Growth Marks.

    Directory of Open Access Journals (Sweden)

    Jesse C Leland

    Full Text Available Recent studies have reported that crustacean age determination is possible. We applied a direct ageing method (i.e. transverse cross sectioning of gastric ossicles to a subtropical freshwater crayfish (Cherax quadricarinatus sourced from an aquaculture population. Growth mark periodicity and the potential for chronological depositions were investigated by staining C. quadricarinatus with calcein and examining their ossicles a year later. Pterocardiac ossicles were superior to other ageing structures (i.e. other ossicles and eyestalks and produced repeatable between-reader counts (87% were corroborated and 13% varied by ±1. C. quadricarinatus size-at-age data (for an aquaculture population was described by a von Bertalanffy growth equation (L∞ = 32 mm occipital carapace length; K = 0.64; t0 = -0.18; R2 = 0.81. Ossicular growth marks did not correspond to moult history. The calcein stain was retained over an annual cycle comprising multiple moults, demonstrating that pterocardiac ossicles retain chronological information. The maximum age (3+ corroborated other indirectly-obtained longevity estimates for C. quadricarinatus. Multiple lines of evidence indicate that the growth marks in C. quadricarinatus ossicles are probably deposited annually during winter. The ability to extract age information from subtropical decapods provides substantial opportunities for advancing fisheries and conservation research globally, but further research is needed to provide a definitive validation and elucidate the mechanism governing the accrual of ossicular growth marks.

  12. Determinants of labor market choices : age differentials and family circumstances

    OpenAIRE

    Kutyavina, Marina

    2015-01-01

    My research explores the interactions between labor market choices, public programs, and family circumstances. In the following three chapters, I study the relationship between labor market conditions and job search behavior of workers of differing ages, the effect of children's events on parental retirement timing, as well as the impact of UI extensions on recipients' spouses

  13. Age and dose as determinants of times of appearance of radium-induced osteosarcomas in humans

    International Nuclear Information System (INIS)

    Determinants of time-until-tumor for bone sarcomas in US radium cases have been reevaluated. For the 57 measured female bone sarcoma cases exposed to 226Ra and/or 228Ra, ages at appearance of tumor are more strongly correlated with radium intake doses than are latency periods. Ages at appearance of tumor increase as initial radium intakes decrease. As many lower dose cases were iatrogenic cases exposed in mid-adult life, rather than about age 22 as for the dial worker cases, these results may be artifactual, resulting from an increased susceptability to sarcoma induction at older ages. Alternatively the time of appearance of a sarcoma may be in part directly determined by age. Both explanations find support in the literature. These results suggest that 226228Ra-induced bone sarcomas do have an expression period. The downturn in sarcoma incidence at very high doses may result from truncation of the expression period on its early side by the minimum induction period

  14. The determination of the age of Globular Clusters a statistical approach

    CERN Document Server

    Rengel, M; Bruzual, A G; Rengel, Miriam; Mateu, Juan; Bruzual, Gustavo

    2001-01-01

    We present a statistical approach for determining the age of Globular Clusters (GCs) that allows estimating the age derived from CMDs more accurately than the conventional methods of the isochrone fitting. We measure how closely a set of synthetic CMDs constructed from different evolutionary models resemble the observed ones by determining the likelihood using Saha and Chi-square statistics. The model which best matches the observational data, of a set of plausible ones, is the one with the highest value of the estimator. We apply this method to a set of three different evolutionary models presented by three different authors. Each of theses sets consists again of many different models of various chemical abundances, ages, input physics and there alike. We subsequently derive the age of GCs NGC 6397, M92 and M3. With a confidence level of 99%, we find that the best estimate of the age is 14.0 Gyrs within the range of 13.8 to 14.4 Gyrs for NGC 6397, 14.75 Gyrs within the range of 14.50 to 15.40 Gyrs for M92, a...

  15. Identifying the genomic determinants of aging and longevity in human population studies: Progress and challenges

    OpenAIRE

    Deelen, Joris; Beekman, Marian; Capri, Miriam; FRANCESCHI, Claudio; Slagboom, P. Eline

    2013-01-01

    Human lifespan variation is mainly determined by environmental factors, whereas the genetic contribution is 25–30% and expected to be polygenic. Two complementary fields go hand in hand in order to unravel the mechanisms of biological aging: genomic and biomarker research. Explorative and candidate gene studies of the human genome by genetic, transcriptomic, and epigenomic approaches have resulted in the identification of a limited number of interesting positive linkage regions, genes, and pa...

  16. Texture determination by neutron diffraction

    International Nuclear Information System (INIS)

    Application of neutron diffraction to crystallographic texture determination shows many advantages: possibility of an important grain size, the quantity of material contributing to diffraction is more important than with X rays, good accuracy and complete pole figures are obtained by transmission only eliminating corrections needed with X rays. Texture determination allows control and improvement of material quality. Texture studies give good informations on mechanisms occuring in deformation or recrystallization of polycrystals and on anisotropy of physical and mechanical properties

  17. Dem Bones: Forensic Resurrection of a Skeleton.

    Science.gov (United States)

    Bruce, Alease

    2001-01-01

    Presents an activity for students to determine the sex and age of an individual from a collection of bones. Simulates some of the actual procedures conducted in a forensic anthropologist's lab, examining and identifying bones through a series of lab activities. (Author/ASK)

  18. Aging is a weak but relentless determinant of dementia severity

    OpenAIRE

    Royall, Donald R.; Raymond F. Palmer

    2016-01-01

    Structural Equation Models (SEM) can explicitly distinguish “dementia-relevant” variance in cognitive task performance (i.e., “δ” for dementia). In prior work, δ appears to uniquely account for dementia severity regardless of the cognitive measures used to construct it. In this study, we test δ as a mediator of age's prospective association with future cognitive performance and dementia severity in a large, ethnically diverse longitudinal cohort, the Texas Alzheimer's Research and Care Consor...

  19. Lifestyle and dietary factors determine age at natural menopause

    OpenAIRE

    Sapre, Shilpa; Thakur, Ratna

    2014-01-01

    A literature search was done using PubMed. The age at natural menopause (ANM) depends on various factors like genetic, environmental, socioeconomic, reproductive, dietary, and lifestyle of which some like nulliparity, vegetarian diet, smoking, high fat intake, cholesterol, and caffeine accelerates; while others like parity, prior use of oral contraceptive pills, and Japanese ethnicity delays the ANM. ANM is an important risk factor for long-term morbidity and mortality; and hence, the need to...

  20. ACCELERATED AGING TEST IN DETERMINING THE VIGOUR OF SUNFLOWER SEEDS WITH AND WITHOUT PERICARP

    Directory of Open Access Journals (Sweden)

    K. R. Ducatti

    2014-09-01

    Full Text Available The standard germination test alone is insufficient to attest the quality of seeds, making necessary correlation’s with vigour tests, to determine more accurately the physiological potential of a seeds lot. The accelerated aging test is an option for determine the vigour and consists in submits seeds to high temperatures and humidity, for different periods of time, has not yet standardized. The objective of this work was to analyze the efficiency of the accelerated aging test in the assessment of the effect of a lot of sunflower seed, by three periods of aging (48, 56 and 72 hours in 42 °C temperature, in seeds with and without pericarp (manually removed and relate the results with electrical conductivity test and germination first count. The experimental design was a completely randomized design and the comparison of averages made using Tukey's test at 5% probability. The results showed that standard germination, electrical conductivity and germination first count, the seeds without pericarp showed better performance. In relation to the accelerated aging, only in the period of 72 hours of aging there was no significant difference between the treatments. In this way, the appropriate period to identify differences in force between the treatments was 72 hours, which showed a positive correlation with the germination first count and electrical conductivity.

  1. Identifying the genomic determinants of aging and longevity in human population studies: progress and challenges.

    Science.gov (United States)

    Deelen, Joris; Beekman, Marian; Capri, Miriam; Franceschi, Claudio; Slagboom, P Eline

    2013-04-01

    Human lifespan variation is mainly determined by environmental factors, whereas the genetic contribution is 25-30% and expected to be polygenic. Two complementary fields go hand in hand in order to unravel the mechanisms of biological aging: genomic and biomarker research. Explorative and candidate gene studies of the human genome by genetic, transcriptomic, and epigenomic approaches have resulted in the identification of a limited number of interesting positive linkage regions, genes, and pathways that contribute to lifespan variation. The possibilities to further exploit these findings are rapidly increasing through the use of novel technologies, such as next-generation sequencing. Genomic research is progressively being integrated with biomarker studies on aging, including the application of (noninvasive) deep phenotyping and omics data - generated using novel technologies - in a wealth of studies in human populations. Hence, these studies may assist in obtaining a more holistic perspective on the role of the genome in aging and lifespan regulation. PMID:23423909

  2. LOD +: Augmenting LOD with Skeletons

    OpenAIRE

    Lange, Benoit; Rodriguez, Nancy

    2010-01-01

    Until now computer graphic researchers have tried to solve visualization problems introduced by the size of meshes. Modern tools produce large models and hardware is not able to render them in full resolution. For example, the digital Michelangelo project extracted a model with more than one billion polygons. One can notice hardware has become more and more powerful but meshes have also become more and more complex. To solve this issue, people have worked on many solutions. We can find soluti...

  3. Structural integrity assessment and stress measurement of CHASNUPP-1 fuel assembly skeleton

    International Nuclear Information System (INIS)

    Highlights: • FE model of CHASNUPP-1 FA Skeleton produced, using Shell181 Element. • Non-linear buckling analysis has been performed. • Structural integrity and stress measurement of FA skeleton is calculated. • Test results obtained at each strain gauge is compared with FE results at same locations. • Results of both studies are comparable, which validate the FE methodology. -- Abstract: A fuel assembly (FA) structure without fuel rods is called FA skeleton which is a long and flexible structure. This study has been made in an attempt to find the structural integrity of the Chashma Nuclear Power Plant-1 (CHASNUPP-1) FA Skeleton at room temperature in air. Non-linear buckling analysis has been performed using ANSYS 13.0, in-order to determine the buckling behavior of the FA skeleton as well as the location/values of the maximum stress intensity and stresses developed in axial direction under applied compression load of 4900 N. The finite element (FE) model of spacer grids, guide thimbles with dash-pots and flow holes, in addition to spot welds between spacer grids and guide thimbles, has been developed using Shell 181 element. The FA skeleton is a non-straight structure. Its actual behavior of the geometry is non-linear. The value of the perturbation force is related to the geometry of the model and/or the tolerance defined for the geometry. Therefore, a sensitivity study has been made to determine the appropriate value of an arbitrary perturbation load. It has been observed that FA skeleton deformation values obtained through FE Analysis and Experiment (Technical Report, 1994a,b) under applied compression load are comparable and show linear behaviors. Therefore, it is confirmed that buckling of FA skeleton will not occur at the specified load. Moreover, the values of stresses obtained at different locations of the guide thimbles are also comparable with the stress values of the experiment determined at the same locations through strain gauges. Since the

  4. Non-rigid registration of small animal skeletons from micro-CT using 3D shape context

    Science.gov (United States)

    Xiao, Di; Bourgeat, Pierrick; Fripp, Jurgen; Acosta Tamayo, Oscar; Gregoire, Marie Claude; Salvado, Olivier

    2009-02-01

    Small animal registration is an important step for molecular image analysis. Skeleton registration from whole-body or only partial micro Computerized Tomography (CT) image is often performed to match individual rats to atlases and templates, for example to identify organs in positron emission tomography (PET). In this paper, we extend the shape context matching technique for 3D surface registration and apply it for rat hind limb skeleton registration from CT images. Using the proposed method, after standard affine iterative closest point (ICP) registration, correspondences between the 3D points from sour and target objects were robustly found and used to deform the limb skeleton surface with thin-plate-spline (TPS). Experiments are described using phantoms and actual rat hind limb skeletons. On animals, mean square errors were decreased by the proposed registration compared to that of its initial alignment. Visually, skeletons were successfully registered even in cases of very different animal poses.

  5. Pavement Aging Model by Response Surface Modeling

    Directory of Open Access Journals (Sweden)

    Manzano-Ramírez A.

    2011-10-01

    Full Text Available In this work, surface course aging was modeled by Response Surface Methodology (RSM. The Marshall specimens were placed in a conventional oven for time and temperature conditions established on the basis of the environment factors of the region where the surface course is constructed by AC-20 from the Ing. Antonio M. Amor refinery. Volatilized material (VM, load resistance increment (ΔL and flow resistance increment (ΔF models were developed by the RSM. Cylindrical specimens with real aging were extracted from the surface course pilot to evaluate the error of the models. The VM model was adequate, in contrast (ΔL and (ΔF models were almost adequate with an error of 20 %, that was associated with the other environmental factors, which were not considered at the beginning of the research.

  6. CARBON STOCK DETERMINATION IN TEAK (Tectona grandis L. f. AT DIFFERENT AGES

    Directory of Open Access Journals (Sweden)

    Eleusa Maria Almeida

    2010-12-01

    Full Text Available The objective of this study was to evaluate the quantity of carbon in teak (Tectona grandis L.f., with 0.5; 1.5; 2.5; 3.5 and 5.5 years of age, during one year. The teak evaluated belonged to the BRASTECA AGROFLORESTAL LTDA company, located in the municipality of Santo Antônio of Leverger, Mato Grosso, Brazil. The carbon stock for each age was assessed every 90 days by determining the amount of litter dry mass, organic carbon proportion in the soil, root density in the soil and the volume of the staff and crown in the three teak trees randomly selected for harvest. The assessment of the plant size, as height, diameter at chest height and crown projection, was carried out with twenty preserved plants at each age. The dry mass of the roots was determined from the relation between the soil volume and the density of roots of the three plants per age, by making four perforations per plant, with six samples for each, up to 0.90 m of depth. The carbon proportion in the soil and in the litter was obtained by age at each collection through laboratory analysis. The average carbon found per hectare was 122.5 t of C at 0.5 years; 104.3 t of C at 1.5 years; 180.8 t of C at 2.5 years; 303.1 t of C at 3.5 years and 322.3 t of C at 5.5 years, considering the numbers of plants per hectare at the different ages. Afterward, the average distribution of carbon per system component was found to be 90.8% in the soil, 5.04% to the aerial part, 3.04% in the roots and 1.21% in the litter.

  7. Age of a prehistoric "Rodedian" cult site constrained by sediment and rock surface luminescence dating techniques

    DEFF Research Database (Denmark)

    Sohbati, Reza; Murray, Andrew; Porat, N.;

    2015-01-01

    The construction age of a pavement in a “Rodedian” prehistoric cult site in Negev desert, Israel, is established by determining the burial age of (i) a cobble used in the pavement, and (ii) the underlying sediment. The quartz OSL age and the K-feldspar corrected IR50 age from the sediment...

  8. CAG repeat expansion in Huntington disease determines age at onset in a fully dominant fashion

    Science.gov (United States)

    Lee, J.-M.; Ramos, E.M.; Lee, J.-H.; Gillis, T.; Mysore, J.S.; Hayden, M.R.; Warby, S.C.; Morrison, P.; Nance, M.; Ross, C.A.; Margolis, R.L.; Squitieri, F.; Orobello, S.; Di Donato, S.; Gomez-Tortosa, E.; Ayuso, C.; Suchowersky, O.; Trent, R.J.A.; McCusker, E.; Novelletto, A.; Frontali, M.; Jones, R.; Ashizawa, T.; Frank, S.; Saint-Hilaire, M.H.; Hersch, S.M.; Rosas, H.D.; Lucente, D.; Harrison, M.B.; Zanko, A.; Abramson, R.K.; Marder, K.; Sequeiros, J.; Paulsen, J.S.; Landwehrmeyer, G.B.; Myers, R.H.; MacDonald, M.E.; Durr, Alexandra; Rosenblatt, Adam; Frati, Luigi; Perlman, Susan; Conneally, Patrick M.; Klimek, Mary Lou; Diggin, Melissa; Hadzi, Tiffany; Duckett, Ayana; Ahmed, Anwar; Allen, Paul; Ames, David; Anderson, Christine; Anderson, Karla; Anderson, Karen; Andrews, Thomasin; Ashburner, John; Axelson, Eric; Aylward, Elizabeth; Barker, Roger A.; Barth, Katrin; Barton, Stacey; Baynes, Kathleen; Bea, Alexandra; Beall, Erik; Beg, Mirza Faisal; Beglinger, Leigh J.; Biglan, Kevin; Bjork, Kristine; Blanchard, Steve; Bockholt, Jeremy; Bommu, Sudharshan Reddy; Brossman, Bradley; Burrows, Maggie; Calhoun, Vince; Carlozzi, Noelle; Chesire, Amy; Chiu, Edmond; Chua, Phyllis; Connell, R.J.; Connor, Carmela; Corey-Bloom, Jody; Craufurd, David; Cross, Stephen; Cysique, Lucette; Santos, Rachelle Dar; Davis, Jennifer; Decolongon, Joji; DiPietro, Anna; Doucette, Nicholas; Downing, Nancy; Dudler, Ann; Dunn, Steve; Ecker, Daniel; Epping, Eric A.; Erickson, Diane; Erwin, Cheryl; Evans, Ken; Factor, Stewart A.; Farias, Sarah; Fatas, Marta; Fiedorowicz, Jess; Fullam, Ruth; Furtado, Sarah; Garde, Monica Bascunana; Gehl, Carissa; Geschwind, Michael D.; Goh, Anita; Gooblar, Jon; Goodman, Anna; Griffith, Jane; Groves, Mark; Guttman, Mark; Hamilton, Joanne; Harrington, Deborah; Harris, Greg; Heaton, Robert K.; Helmer, Karl; Henneberry, Machelle; Hershey, Tamara; Herwig, Kelly; Howard, Elizabeth; Hunter, Christine; Jankovic, Joseph; Johnson, Hans; Johnson, Arik; Jones, Kathy; Juhl, Andrew; Kim, Eun Young; Kimble, Mycah; King, Pamela; Klimek, Mary Lou; Klöppel, Stefan; Koenig, Katherine; Komiti, Angela; Kumar, Rajeev; Langbehn, Douglas; Leavitt, Blair; Leserman, Anne; Lim, Kelvin; Lipe, Hillary; Lowe, Mark; Magnotta, Vincent A.; Mallonee, William M.; Mans, Nicole; Marietta, Jacquie; Marshall, Frederick; Martin, Wayne; Mason, Sarah; Matheson, Kirsty; Matson, Wayne; Mazzoni, Pietro; McDowell, William; Miedzybrodzka, Zosia; Miller, Michael; Mills, James; Miracle, Dawn; Montross, Kelsey; Moore, David; Mori, Sasumu; Moser, David J.; Moskowitz, Carol; Newman, Emily; Nopoulos, Peg; Novak, Marianne; O'Rourke, Justin; Oakes, David; Ondo, William; Orth, Michael; Panegyres, Peter; Pease, Karen; Perlman, Susan; Perlmutter, Joel; Peterson, Asa; Phillips, Michael; Pierson, Ron; Potkin, Steve; Preston, Joy; Quaid, Kimberly; Radtke, Dawn; Rae, Daniela; Rao, Stephen; Raymond, Lynn; Reading, Sarah; Ready, Rebecca; Reece, Christine; Reilmann, Ralf; Reynolds, Norm; Richardson, Kylie; Rickards, Hugh; Ro, Eunyoe; Robinson, Robert; Rodnitzky, Robert; Rogers, Ben; Rosenblatt, Adam; Rosser, Elisabeth; Rosser, Anne; Price, Kathy; Price, Kathy; Ryan, Pat; Salmon, David; Samii, Ali; Schumacher, Jamy; Schumacher, Jessica; Sendon, Jose Luis Lópenz; Shear, Paula; Sheinberg, Alanna; Shpritz, Barnett; Siedlecki, Karen; Simpson, Sheila A.; Singer, Adam; Smith, Jim; Smith, Megan; Smith, Glenn; Snyder, Pete; Song, Allen; Sran, Satwinder; Stephan, Klaas; Stober, Janice; Sü?muth, Sigurd; Suter, Greg; Tabrizi, Sarah; Tempkin, Terry; Testa, Claudia; Thompson, Sean; Thomsen, Teri; Thumma, Kelli; Toga, Arthur; Trautmann, Sonja; Tremont, Geoff; Turner, Jessica; Uc, Ergun; Vaccarino, Anthony; van Duijn, Eric; Van Walsem, Marleen; Vik, Stacie; Vonsattel, Jean Paul; Vuletich, Elizabeth; Warner, Tom; Wasserman, Paula; Wassink, Thomas; Waterman, Elijah; Weaver, Kurt; Weir, David; Welsh, Claire; Werling-Witkoske, Chris; Wesson, Melissa; Westervelt, Holly; Weydt, Patrick; Wheelock, Vicki; Williams, Kent; Williams, Janet; Wodarski, Mary; Wojcieszek, Joanne; Wood, Jessica; Wood-Siverio, Cathy; Wu, Shuhua; Yastrubetskaya, Olga; de Yebenes, Justo Garcia; Zhao, Yong Qiang; Zimbelman, Janice; Zschiegner, Roland; Aaserud, Olaf; Abbruzzese, Giovanni; Andrews, Thomasin; Andrich, Jurgin; Antczak, Jakub; Arran, Natalie; Artiga, Maria J. Saiz; Bachoud-Lévi, Anne-Catherine; Banaszkiewicz, Krysztof; di Poggio, Monica Bandettini; Bandmann, Oliver; Barbera, Miguel A.; Barker, Roger A.; Barrero, Francisco; Barth, Katrin; Bas, Jordi; Beister, Antoine; Bentivoglio, Anna Rita; Bertini, Elisabetta; Biunno, Ida; Bjørgo, Kathrine; Bjørnevoll, Inga

    2012-01-01

    Objective: Age at onset of diagnostic motor manifestations in Huntington disease (HD) is strongly correlated with an expanded CAG trinucleotide repeat. The length of the normal CAG repeat allele has been reported also to influence age at onset, in interaction with the expanded allele. Due to profound implications for disease mechanism and modification, we tested whether the normal allele, interaction between the expanded and normal alleles, or presence of a second expanded allele affects age at onset of HD motor signs. Methods: We modeled natural log-transformed age at onset as a function of CAG repeat lengths of expanded and normal alleles and their interaction by linear regression. Results: An apparently significant effect of interaction on age at motor onset among 4,068 subjects was dependent on a single outlier data point. A rigorous statistical analysis with a well-behaved dataset that conformed to the fundamental assumptions of linear regression (e.g., constant variance and normally distributed error) revealed significance only for the expanded CAG repeat, with no effect of the normal CAG repeat. Ten subjects with 2 expanded alleles showed an age at motor onset consistent with the length of the larger expanded allele. Conclusions: Normal allele CAG length, interaction between expanded and normal alleles, and presence of a second expanded allele do not influence age at onset of motor manifestations, indicating that the rate of HD pathogenesis leading to motor diagnosis is determined by a completely dominant action of the longest expanded allele and as yet unidentified genetic or environmental factors. Neurology® 2012;78:690–695 PMID:22323755

  9. NF-κB/AP-1-Targeted Inhibition of Macrophage-Mediated Inflammatory Responses by Depigmenting Compound AP736 Derived from Natural 1,3-Diphenylpropane Skeleton

    Directory of Open Access Journals (Sweden)

    Van Thai Ha

    2014-01-01

    Full Text Available AP736 was identified as an antimelanogenic drug that can be used for the prevention of melasma, freckles, and dark spots in skin by acting as a suppressor of melanin synthesis and tyrosinase expression. Since macrophage-mediated inflammatory responses are critical for skin health, here we investigated the potential anti-inflammatory activity of AP736. The effects of AP736 on various inflammatory events such as nitric oxide (NO/prostaglandin (PG E2 production, inflammatory gene expression, phagocytic uptake, and morphological changes were examined in RAW264.7 cells. AP736 was found to strongly inhibit the production of both NO and PGE2 in lipopolysaccharide- (LPS- treated RAW264.7 cells. In addition, AP736 strongly inhibited both LPS-induced morphological changes and FITC-dextran-induced phagocytic uptake. Furthermore, AP736 also downregulated the expression of multiple inflammatory genes, such as inducible NO synthase (iNOS, cyclooxygenase- (COX- 2, and interleukin- (IL- 1β in LPS-treated RAW264.7 cells. Transcription factor analysis, including upstream signalling events, revealed that both NF-κB and AP-1 were targeted by AP736 via inhibition of the IKK/IκBα and IRAK1/TAK1 pathways. Therefore, our results strongly suggest that AP736 is a potential anti-inflammatory drug due to its suppression of NF-κB-IKK/IκBα and AP-1-IRAK1/TAK1 signalling, which may make AP736 useful for the treatment of macrophage-mediated skin inflammation.

  10. [Princess Anna Vasa--her fascinating life story and skeleton].

    Science.gov (United States)

    During, Ebba

    2005-01-01

    The Princess Anna Vasa was born in Sweden in 1568 and spent her first 19 years there. She was the daughter of the Swedish king Johan III and his wife, the Polish Royal Princess Katarina Jagellonica. She was brought up as a Catholic but converted to be a Protestant already in 1583 and remained a fervent Protestant to the end of her life. She was an exceptionally intelligent and extensively educated woman. When her brother became king, Sigismund III of Poland, she accompanied him there. She exerted great influence on Sigismund who was brought up to be a Catholic. She was persistent in her religion, yet working for religious liberty. "The Swedish Princess" was also named "the Queen of Polish Botany". She was never married and she died 57 years old in 1625. For religious reasons her body had to wait 11 years for a funeral of royal standing. The funeral took place in 1636 in St Mary's Church in Torun, Poland. During restoration work at the church in April 1994, Anna Vasa's skeleton was removed from the tomb, and an antropological investigation in order to establish her identity was carried by Dr Andrzej Florkowski at the Dept of Anthrop, Nicholas Copernicus University of Torun. I was invited to Torun to examine her remains in May 1995. The skeleton was in a rather good state of preservation. However, her grave had been plundered at least twice. Her skeleton lacked the right forearm and hand, probably as the result of the pillage of her rings and bracelets. Some other bones and teeth were also missing. At our ocular examination the skeleton revealed a number of anatomical deformations and pathological changes. A conventional radiography and CT of Anna Vasa's skeletal remains was later carried out in 1995 by M. Grzegorzewski, Z. Boron and W. Lasek at the Dept of Radiology, Med. Acad. of Bydgoszcz, Polen. A DNA-analysis was carried out by Dr Anders Götherström at the Archaeol. Res. Lab., Stockholm Univ. An odontological and radiological study was performed by Dr Sigrid I

  11. 1-Skeletons of the Spanning Tree Problems with Additional Constraints

    Directory of Open Access Journals (Sweden)

    V. A. Bondarenko

    2015-10-01

    Full Text Available In this paper, we study polyhedral properties of two spanning tree problems with additional constraints. In the first problem, it is required to find a tree with a minimum sum of edge weights among all spanning trees with the number of leaves less than or equal to a given value. In the second problem, an additional constraint is the assumption that the degree of all nodes of the spanning tree does not exceed a given value. The recognition versions of both problems are NP-complete. We consider polytopes of these problems and their 1-skeletons. We prove that in both cases it is a NP-complete problem to determine whether the vertices of 1-skeleton are adjacent. Although it is possible to obtain a superpolynomial lower bounds on the clique numbers of these graphs. These values characterize the time complexity in a broad class of algorithms based on linear comparisons. The results indicate a fundamental difference between combinatorial and geometric properties of the considered problems from the classical minimum spanning tree problem.

  12. 20 CFR 410.426 - Determining total disability: Age, education, and work experience criteria.

    Science.gov (United States)

    2010-04-01

    ... 20 Employees' Benefits 2 2010-04-01 2010-04-01 false Determining total disability: Age, education, and work experience criteria. 410.426 Section 410.426 Employees' Benefits SOCIAL SECURITY... Disability or Death Due to Pneumoconiosis § 410.426 Determining total disability: Age, education, and...

  13. Gujarati Handwritten Numeral Optical Character through Neural Network and Skeletonization

    Directory of Open Access Journals (Sweden)

    moro kamal

    2013-07-01

    Full Text Available This paper deals with an optical character recognition (OCR system for handwritten Gujarati numbers. One may find so much of work for Indian languages like Hindi, Kannada, Tamil, Bangala, Malayalam, Gurumukhi etc, but Gujarati is a language for which hardly any work is traceable especially for handwritten characters. The features of Gujarati digits are abstracted by four different profiles of digits. Skeletonization and binarization are also done for preprocessing of handwritten numerals before their classification. This work has achieved approximately 80,5% of success rate for Gujarati handwritten digit identification.

  14. ODONTOMETRIC ANALYSIS OF THE ALTINTEPE URARTU SKELETONS

    Directory of Open Access Journals (Sweden)

    Pınar GÖZLÜK KIRMIZIOĞLU

    2009-10-01

    Full Text Available It has been shown that under the pressure of natural selection, tooth size varies over time among societies. The study of metric size variation is a common method used by anthropologists to investigate the morphologic relationships in archaeological Anatolian societies. The size, shape, and structure of the tubercles of teeth is primarily determined by genes. The integral role of genes does not only apply to the crown and roots, but also to numerous features of the tooth. In this study conducted at the Urartu Altıntepe site, skeletal measurements were taken to understand the critical differences in size and morphology among the individuals. The data for this study in the Altıntepe necropol area is comprised from 152 individuals from 38 graves from which mesio-distal measurements were taken from 684 permanent teeth and bucco-lingual measurements were collected from 693 permanent teeth. The measurements taken from upper and lower left teeth were graphed in a statistical Cluster analysis to reveal dental similarities in community groups. The data results show that the Altıntepe Urartu community shares tooth size similarities with the Van-Karagündüz society of the Early Iron Age and the Kütahya Ağızören Hittite society.

  15. Shedding light into the function of the earliest vertebrate skeleton

    Science.gov (United States)

    Martinez-Perez, Carlos; Purnell, Mark; Rayfield, Emily; Donoghue, Philip

    2016-04-01

    Conodonts are an extinct group of jawless vertebrates, the first in our evolutionary lineage to develop a biomineralized skeleton. As such, the conodont skeleton is of great significance because of the insights it provides concerning the biology and function of the primitive vertebrate skeleton. Conodont function has been debated for a century and a half on the basis of its paleocological importance in the Palaezoic ecosystems. However, due to the lack of extanct close representatives and the small size of the conodont element (under a milimiter in length) strongly limited their functional analysis, traditional restricted to analogy. More recently, qualitative approaches have been developed, facilitating tests of element function based on occlusal performance and analysis of microwear and microstructure. In this work we extend these approaches using novel quantitative experimental methods including Synchrotron Radiation X-ray Tomographic Microscopy or Finite Element Analysis to test hypotheses of conodont function. The development of high resolution virtual models of conodont elements, together with biomechanical approaches using Finite Element analysis, informed by occlusal and microwear analyses, provided conclusive support to test hypothesis of structural adaptation within the crown tissue microstructure, showing a close topological co-variation patterns of compressive and tensile stress distribution with different crystallite orientation. In addition, our computational analyses strongly support a tooth-like function for many conodont species. Above all, our study establishes a framework (experimental approach) in which the functional ecology of conodonts can be read from their rich taxonomy and phylogeny, representing an important attempt to understand the role of this abundant and diverse clade in the Phanerozoic marine ecosystems.

  16. Erythrocyte membrane proteins and membrane skeleton

    Institute of Scientific and Technical Information of China (English)

    LU Yiqin; LIU Junfan

    2007-01-01

    Considerable advances in the research field of erythrocyte membrane were achieved in the recent two decades.New findings in the structure-function correlation and interactions of erythrocyte membrane proteins have attracted extensive attention.Interesting progress was also made in the molecular pathogenesis of erythrocyte membrane disorders.Advances in the composition,function and interaction of erythrocyte membrane proteins,erythrocyte membrane skeleton,and relevant diseases are briefly described and summarized here on the basis of domestic and world literatures.

  17. Regional cerebral blood flow in aged diabetic patients without a history of cerebrovascular accident, determined by N-isopropyl- sup 123 I-p-iodoamphetamine with single photon emission CT

    Energy Technology Data Exchange (ETDEWEB)

    Wakisaka, Masanori; Nagamachi, Shigeki; Inoue, Kenjiro; Morotomi, Yasuyuki (National Sanatorium Miyazaki Higashi Hospital (Japan)); Nunoi, Kiyohide; Fujishima, Masatoshi

    1989-07-01

    N-isopropyl-{sup 123}I-p-iodoamphetamine (IMP) was used to determine the regional cerebral blood flow in 9 diabetic patients (average age: 71.8 years) and 9 non-diabetic subjects (average age: 71.7 years), none of whom had a history of cerebrovascular accident. There were no significant differences in the physiological or laboratory data between the diabetic and non-diabetic groups except in fasting plasma glucose and HbA{sub 1}c levels. Areas of hypoperfusion of the cerebral hemispheres were observed in 7 diabetic patients, 5 of whom showed multiple lesions. On the other hand, areas of hypoperfusion were observed only in 4 of the non-diabetic subjects and only 1 of these demonstrated multiple lesions. We evaluated the cerebral blood flow semiquantitatively as follows: the area where the radioactive count was 65% or more of the maximum count of the slice was defined as a region of normal cerebral blood flow (ROI-A); the area where the count was 45% or more as region of brain tissue except for ventricles (RUI-B). The numbers of pixels of ROI-A and ROI-B were counted in each slice and the ROI-A/B ratios of 16 slices were averaged individually. The average percent ROI-A/B ratio was significantly lower in the diabetic group than that in the control group (49.4+-1.9 (Mean+-SEM) vs 56.6+-1.9%, p<0.05). These observations suggest that the area of normal regional cerebral blood flow is reduced in aged diabetics, even in the absence of a history of cerebrovascular accident. (author).

  18. Regional cerebral blood flow in aged diabetic patients without a history of cerebrovascular accident, determined by N-isopropyl-123I-p-iodoamphetamine with single photon emission CT

    International Nuclear Information System (INIS)

    N-isopropyl-123I-p-iodoamphetamine (IMP) was used to determine the regional cerebral blood flow in 9 diabetic patients (average age: 71.8 years) and 9 non-diabetic subjects (average age: 71.7 years), none of whom had a history of cerebrovascular accident. There were no significant differences in the physiological or laboratory data between the diabetic and non-diabetic groups except in fasting plasma glucose and HbA1c levels. Areas of hypoperfusion of the cerebral hemispheres were observed in 7 diabetic patients, 5 of whom showed multiple lesions. On the other hand, areas of hypoperfusion were observed only in 4 of the non-diabetic subjects and only 1 of these demonstrated multiple lesions. We evaluated the cerebral blood flow semiquantitatively as follows: the area where the radioactive count was 65% or more of the maximum count of the slice was defined as a region of normal cerebral blood flow (ROI-A); the area where the count was 45% or more as region of brain tissue except for ventricles (RUI-B). The numbers of pixels of ROI-A and ROI-B were counted in each slice and the ROI-A/B ratios of 16 slices were averaged individually. The average percent ROI-A/B ratio was significantly lower in the diabetic group than that in the control group (49.4±1.9 (Mean±SEM) vs 56.6±1.9%, p<0.05). These observations suggest that the area of normal regional cerebral blood flow is reduced in aged diabetics, even in the absence of a history of cerebrovascular accident. (author)

  19. Determination of the lactate threshold and maximal blood lactate steady state intensity in aged rats.

    Science.gov (United States)

    Cunha, Rafael Rodrigues; Cunha, Verusca Najara de Carvalho; Segundo, Paulo Russo; Moreira, Sérgio Rodrigues; Kokubun, Eduardo; Campbell, Carmen Sílvia Grubert; de Oliveira, Ricardo Jacó; Simões, Herbert Gustavo

    2009-08-01

    The reliability of the lactate threshold (LT) determined in aged rats and its validity to identify an exercise intensity corresponding to the maximal blood lactate steady state (MLSS) were analyzed. Eighteen male aged Wistar rats (approximately 365 days) were submitted to two incremental swimming tests until exhaustion, consisting of an initial load corresponding to 1% of body mass (BM) and increments of 1% BM at each 3-min with blood lactate ([lac]) measurements. The LT was determined by visual inspection (LT(V)) as well by applying a polynomial function on the [lac]/workload ratio (LT(P)) by considering the vertices of the curve. For the MLSS, twelve animals were submitted, on different days, to 3-4 exercise sessions of 30-min with workload corresponding to 4, 5 or 6% BM. The MLSS was considered the highest exercise intensity at which the [lac] variation was not higher than 0.07 mM.min(-1) during the last 20-min. No differences were observed for the test-retest results (4.9 +/- 0.7 and 5.0 +/- 0.8 %BM for LTv; and 6.0 +/- 0.6 and 5.8 +/- 0.6 %BM for LTp) that did not differ from the MLSS (5.4 +/- 0.5 %BM). The LT identified for aged rats in swimming, both by visual inspection and polynomial function, was reliable and did not differ from the MLSS. PMID:19585487

  20. 不同年生西洋参中20种有机氯农药的气相色谱分析%Determination of Organochlorine Pesticides in Panax quinquefolium L. with Different Ages by Gas Chromatography

    Institute of Scientific and Technical Information of China (English)

    秦公伟; 曹小勇; 耿敬章; 张静; 陈玉芳; 陈富东

    2012-01-01

    a high performance gas chromatography method has been developed for determining 20 kinds of organochlorine pesticides including α-BHC and 4,4'-DDT in American ginseng(Panax quinquefolium L.) grown in different areas of GAP plantation base from Liuba county,shaanxi province.The accumulation of organochlorine pesticides in American ginseng with different ages was also explored.Organochlorine pesticides in samples were extracted by hexane-ethyl acetate(1:1) solution,and then purified by a column packed with Florisil using hexane-ethyl acetate(1:1) as elution solvent.Chromatographic analysis was performed on a DB-17 capillary column supplemented with electron capture detector(ECD).A total of 19 organochlorine pesticides except for endrin were detected.The contents of organochlorine pesticides in samples from different areas revealed an obvious difference.Moreover,the residues of organochlorine pesticides in four-year-old American ginseng were higher than those in three-year-old or five-year-old American ginseng.Therefore,this developed method is effective,fast and accurate,which can be used for determining 20 kinds of organochlorine pesticides in American ginseng.%建立西洋参中α-六六六(α-BHC)、4,4'-滴滴涕(4,4'-DDT)等20种有机氯农药残留量的一种简便有效的气相色谱分析方法,对陕西留坝县西洋参GAP生产基地不同种植地块、不同生长年限西洋参中有机氯农药的种类和含量进行测定,并探讨不同生长年限西洋参中有机氯农药富集规律。样品有机氯农药残留用正己烷-乙酸乙酯(1:1)溶液提取,通过弗罗里硅土小柱净化,正己烷-乙酸乙酯(1:1)溶液洗脱后浓缩定容,采用DB-17毛细管柱分离,气相色谱-电子捕获检测器(gas chromatography-electron capture detector,GC-ECD)检测,以保留时间定性,外标法定量。结果表明:10个西洋参样品中除异狄氏剂未检出外,标准溶液中的其他19

  1. Modification of diphenylamine-linked bis(oxazoline)ligands:Tuning of electronic effect and rigidity of ligand skeleton

    Institute of Scientific and Technical Information of China (English)

    LIU Han; LI Wei; DU DaMing

    2009-01-01

    The electronic effect of diphenylamine-linked bis(oxazoline) ligands was tuned through introduction of electron-withdrawing bromo and nitro substituents onto the 4 and 4' position.The variation of the NH bond acidity was determined by the different chemical shifts of NH.The catalytic activity and enantioselectivity of the modified ligands were tested in the asymmetric FriedeI-Crafts alkylation of indole with β-nitrostyrene.The effect of iigand skeleton rigidity was also investigated through the synthesis of iminodibenzyl-linked bis(oxazoline) ligands and evaluation of their catalytic activity in Friedel-Crafts alkylation.

  2. Modification of diphenylamine-linked bis(oxazoline) ligands: Tuning of electronic effect and rigidity of ligand skeleton

    Institute of Scientific and Technical Information of China (English)

    2009-01-01

    The electronic effect of diphenylamine-linked bis(oxazoline) ligands was tuned through introduction of electron-withdrawing bromo and nitro substituents onto the 4 and 4′ position. The variation of the NH bond acidity was determined by the different chemical shifts of NH. The catalytic activity and enantioselectivity of the modified ligands were tested in the asymmetric Friedel-Crafts alkylation of indole with β-nitrostyrene. The effect of ligand skeleton rigidity was also investigated through the synthesis of iminodibenzyl-linked bis(oxazoline) ligands and evaluation of their catalytic activity in Friedel-Crafts alkylation.

  3. NMR spectroscopy of lactate in the skeleton muscle: visibility, quantification and measurement of carbon 13 enrichment by double quantum edition; Spectroscopie RMN du lactate dans le muscle squeletique: visibilite, quantification et mesure de l'enrichissement au carbone 13 par edition a double quantum

    Energy Technology Data Exchange (ETDEWEB)

    Jouvensal, L

    1997-12-18

    The metabolism of skeleton muscles gave rise to numerous research works since the beginning of the century in order to make some reply about the muscle physiology with the will to improve the sport performances or the understanding of muscles diseases. This metabolism is complex and the lactate has an importance place; the purpose of this work is to answer these questions with some strategy studies by nuclear magnetic resonance spectroscopy. (N.C.)

  4. The evaluation of two radiographic methods for age determination of children in an Indian population.

    Science.gov (United States)

    Rai, B

    2008-12-01

    The aim of the present study was to evaluate the applicability of the methods proposed by Nolla and Nicodemo for estimation of dental age and its correction with chronological age. Orthopantograms of 413 patients, aged 6-16 year (70-195 months) were selected to estimate the correlation between dental and chronological age. With both the Nolla and Nicodemo methods, the estimated age was lower than compared to chronological age except for the Nolla method in girls. There were significant correlations between chronological and estimated dental age (by Nolla and Nicodemo methods) in both genders. PMID:22717786

  5. Objective criteria for determination of functional-reserve potentials of secondary school age pupils

    Directory of Open Access Journals (Sweden)

    Bodnar I.R.

    2015-11-01

    Full Text Available Purpose: to substantiate criteria for determination of functional-reserve potentials of secondary school age pupils. Material: 1017 pupils of 5-9 forms from 16 schools were questioned. Besides, 200 physical culture teachers from 75 schools of 25 Ukrainian cities were questioned. 154 schoolchildren were tested/ Physical fitness and health levels were tested by index. Pupils fulfilled 4 simple test exercises. Results: we determined indicators of physical condition, psychic state, scopes of motor functioning. We substantiated criteria for determination of schoolchildren’s functional-reserve potentials as well as values of boundary physical condition and physical fitness indicators, which guarantee strong health and optimal functional-reserve potentials of pupil’s organism. Conclusions: Deviation of these indicators’ complex from boundary values informs about pupils’ potential belonging to group of risk. It requires correction of pupil’s way of life and his (her motor functioning.

  6. [Determination of amanitatoxins by HPLC].

    Science.gov (United States)

    Nishizawa, Chiemi; Yamaura, Yoshio

    2003-10-01

    High-performance liquid chromatographic (HPLC) assay has been developed for the simultaneous determination of alpha-amanitin, beta-amanitin and phalloidin in serum. Three toxins were extracted by reflux in a water bath at 80 degrees C for one hour and purified by Sep-Pak Plus tC18 cartridges. The HPLC assay was performed under gradient conditions using Develosil RP AQUEOUS column. The moble phase consisted with a mixture of acetonitorile containing 0.01 M ammonium acetate(pH 5.0). The column effluence was monitored at 295 nm, 302 nm and 230 nm for 35 min. Detection limit of three toxins in serum were 0.2 microgram/ml respectively. High recovery yields in the range of 81.5-88.1% for toxins were obtained by using this method. PMID:14740566

  7. Absolute ages from crater statistics: Using radiometric ages of Martian samples for determining the Martian cratering chronology

    Science.gov (United States)

    Neukum, G.

    1988-01-01

    In the absence of dates derived from rock samples, impact crater frequencies are commonly used to date Martian surface units. All models for absolute dating rely on the lunar cratering chronology and on the validity of its extrapolation to Martian conditions. Starting from somewhat different lunar chronologies, rather different Martian cratering chronologies are found in the literature. Currently favored models are compared. The differences at old ages are significant, the differences at younger ages are considerable and give absolute ages for the same crater frequencies as different as a factor of 3. The total uncertainty could be much higher, though, since the ratio of lunar to Martian cratering rate which is of basic importance in the models is believed to be known no better than within a factor of 2. Thus, it is of crucial importance for understanding the the evolution of Mars and determining the sequence of events to establish an unambiguous Martian cratering chronology from crater statistics in combination with clean radiometric ages of returned Martian samples. For the dating goal, rocks should be as pristine as possible from a geologically simple area with a one-stage emplacement history of the local formation. A minimum of at least one highland site for old ages, two intermediate-aged sites, and one very young site is needed.

  8. Simulation of mould filling process for composite skeleton castings

    Directory of Open Access Journals (Sweden)

    M. Dziuba

    2008-04-01

    Full Text Available In this work authors showed selected results of simulation and experimental studies on temperature distribution during solidification of skeleton casting and mould filling process. The aim of conducted simulations was the choice of thermal and geometrical parameters for the needs of designed calculations of the skeleton castings and the estimation of the guidelines for the technology of manufacturing. The subject of numerical simulation was the analysis of ability of filling the channels of core by liquid metal at estability technological parameters.. Below the assumptions and results of the initial simulated calculations are presented. The total number of the nodes in the casting was 1920 and of the connectors was 5280 what gave filling of 100% for the nodes and 99,56% for the connectors in the results of the simulation. Together it resulted as 99,78 % of filling the volume of the casting. The nodes and connectors were filled up to the 30 level of the casting in the simulation. The all connectors were filled up to the 25 level of the casting in the simulation. Starting from the 25 level individual connectors at the side surface of the casting weren’t filled up. The connectors weren’t supplied by multi-level getting system. The differences of filling the levels are little (maximally 5 per cent.

  9. Uranium age determination: Separation and analysis of 230Th and 231Pa

    International Nuclear Information System (INIS)

    In this work we focused on the age determination of uranium materials of different uranium enrichment. The radioactive decay of the uranium isotopes provides a chronometer that is inherent to the material, in particular the mother/daughter pairs 234U/230Th and 235U/231Pa can be advantageously used. Due to the relatively long half-lives of 234U (2.46 · 105 years) and 235U (7.04 · 108 years) only minute amounts of daughter nuclides are growing in, therefore both separation of Th and Pa from uranium must be of high chemical recovery and must afford large decontamination factors. Analytical methods for the age determination of uranium samples using the parent/daughter relations 234U/230Th and 235U/231Pa is demonstrated. Thorium is separated from bulk uranium using extraction chromatography and subsequently quantified using square-spectrometry, thermal ionisation mass spectrometry (TIMS) and inductively coupled mass spectrometry (ICP-MS). Protactinium is separated by highly selective sorption of protactinium to silica gel followed by square-spectrometric quantification. The methods were tested and validated using uranium reference materials of different uranium enrichment and of known ages. The experimental results obtained with both methods were found to agree with the assumed ages of the reference materials within the combined uncertainty of the measurement. The analysis exploiting the parent/daughter pair 235U/231Pa exhibits a slightly larger combined uncertainty and bias than the thorium method but is found valuable in validating the experimental results by means of a second, independent analysis

  10. An accurate 3D shape context based non-rigid registration method for mouse whole-body skeleton registration

    Science.gov (United States)

    Xiao, Di; Zahra, David; Bourgeat, Pierrick; Berghofer, Paula; Acosta Tamayo, Oscar; Wimberley, Catriona; Gregoire, Marie C.; Salvado, Olivier

    2011-03-01

    Small animal image registration is challenging because of its joint structure, and posture and position difference in each acquisition without a standard scan protocol. In this paper, we face the issue of mouse whole-body skeleton registration from CT images. A novel method is developed for analyzing mouse hind-limb and fore-limb postures based on geodesic path descriptor and then registering the major skeletons and fore limb skeletons initially by thin-plate spline (TPS) transform based on the obtained geodesic paths and their enhanced correspondence fields. A target landmark correction method is proposed for improving the registration accuracy of the improved 3D shape context non-rigid registration method we previously proposed. A novel non-rigid registration framework, combining the skeleton posture analysis, geodesic path based initial alignment and 3D shape context model, is proposed for mouse whole-body skeleton registration. The performance of the proposed methods and framework was tested on 12 pairs of mouse whole-body skeletons. The experimental results demonstrated the flexibility, stability and accuracy of the proposed framework for automatic mouse whole body skeleton registration.

  11. Determinants of vitamin D status in fair-skinned women of childbearing age at northern latitudes.

    Directory of Open Access Journals (Sweden)

    Linnea Hedlund

    Full Text Available BACKGROUND AND OBJECTIVE: Poor vitamin D status during pregnancy has been associated with unfavorable outcomes for mother and child. Thus, adequate vitamin D status in women of childbearing age may be important. The aim of this study is to investigate the determinants of 25-hydroxyvitamin D (25(OHD serum concentrations in women of childbearing age living in Sweden, at latitude 57-58° north. METHOD: Eighty four non-pregnant, non-lactating, healthy, fair-skinned women aged between 25-40 years were included. All subjects provided blood samples, four day food records and answered questionnaires about sun exposure and lifestyle. Total serum 25(OHD was analyzed using Roche Cobas® electrochemoluminiescent immunoassay. RESULTS: Mean 25(OHD was 65.8±19.9 nmol/l and 23% of the subjects had concentrations <50 nmol/l. Only 1% had concentrations <25 nmol/l. Determinants of 25(OHD concentrations were recent sunbed use, recent travel to southern latitude, season, estrogen contraceptive use and use of supplementary vitamin D (R(2 = 0.27. CONCLUSION: Every fifth woman had 25(OHD concentrations <50 nmol/l. About 30% of the variation in vitamin D status was explained by sun exposure, use of vitamin D supplements and use of estrogen contraceptives. Cutaneous vitamin D synthesis seems to be a major contributor to vitamin D status, even at northern latitudes. Thus, recommendations on safe UV-B exposure could be beneficial for vitamin D status.

  12. The postcranial skeletons of the Triassic mammals Eozostrodon, Megazostrodon and Erythrotherium.

    Science.gov (United States)

    Jenkins, F A; Parrington, F R

    1976-02-26

    The purposes of this monograph are to describe the postcranial skeletons of the earliest known mammals, and to probe, in so far as possible by osteological study, biological questions concerning the habits and adaptations of these late Triassic forms. In this context, information on the background of this investigation is useful. Studies of Mesozoic mammals, begun some 150 years ago, are based on rare and fragmentary fossils, principally jaws and teeth. These investigations have yielded a bare outline of some 120 million years of mammalian evolution-about two-thirds of mammalian history. No assessment of the important biological changes occurring during this time can ever be complete, but major advances are possible as new discoveries provide material that is more complete or that represents a previously unknown evolutionary stage. So tenuous is the evidence that at least some concepts are re-evaluated with each discovery. Postcranial anatomy offers especially intriguing prospects for investigation because associated material (that can be positively assigned to a taxon below subclass) has been for the most part unknown, and indeed even dissociated bones are a rarity. Since G.G. Simpson's monographs of 1928 and 1929, progress in the study of Mesozoic mammals has been largely dependent on new finds. A major impetus to renewed investigation came from the discoveries of Mesozoic mammals by Walter Kühne in 1939 and during the immediate post-war years. Kühne first worked on fissures in the Carboniferous limestone quarries at Frome, Somerset, in southwest England where he collected a series of teeth of the problematical form Haramiya and two triconodont teeth which were placed in the genus Eozostrodon (Parrington 1941, 1946). The fissure faunas are generally thought to be of Upper Triassic (Rhaetic) age (Kühne 1946), although Kermack, Musset & Rigney (1973) believe that the evidence is insufficient to determine whether the deposits are Rhaetic or Lower Liassic. After

  13. Why is age determination of Baltic cod (Gadus morhua) so difficult?

    DEFF Research Database (Denmark)

    Hüssy, Karin

    2010-01-01

    consistent pattern the following year, and overlap was not influenced by sex or fish size. The results suggest that otolith opacity in Baltic cod is not associated with seasonal patterns in daily increment structure and that traditional age determination based on otolith opacity yields highly uncertain......The aim of this study was to evaluate the consistency of three methods for assigning annuli in adult Baltic cod otoliths. The methods examined were (i) daily increment patterns, (ii) opacity profiles, and (iii) traditional age reading. Frequency distributions of the distance from the nucleus to the...... similar to opacity patterns. However, within individual fish, the co-occurrence of overlap between the two patterns was random. In cases where there was overlap, translucent zone formation started just before the disappearance of visible increments. Overlap in 1 year did not necessarily lead to a...

  14. Orange roughy: their age unlocked by radioisotopes

    International Nuclear Information System (INIS)

    A radiometric method was developed and applied to try and solve the question of age for orange roughy, currently the primary target species in the south east trawl fishery. The method involved measuring the natural levels of the radioactive elements radium-226 and lead-210 present in the otolith of the fish. Radium-226 is chemically similar to calcium and, as such, is taken up by fish and laid-down in their otoliths as the fish grows. It was found that orange roughy is a very slow growing and long-lived species with fish 38-40 cm SL ranging between 77 and 149 years old. The results also indicated that maturity is around 32 years which occurs at about 32 cm SL. 4 refs., 1 tab., ills

  15. U-Pb systematics of the unique achondrite Ibitira: Precise age determination and petrogenetic implications

    Science.gov (United States)

    Iizuka, Tsuyoshi; Amelin, Yuri; Kaltenbach, Angela; Koefoed, Piers; Stirling, Claudine H.

    2014-05-01

    Ibitira is an unbrecciated, equilibrated vesicular basaltic achondrite that is considered to have originated on a parent body distinct from all other known meteorites. We present the first combined high-precision U and Pb isotopic data for this unique meteorite. The 238U/235U value of 137.777 ± 0.013 determined for the whole rock is comparable to values determined for bulk chondrites and other basaltic achondrites. This value results in corrections of -1.1 Ma for Pb-Pb dates calculated using the previously assumed invariant 238U/235U value of 137.88. Using the determined 238U/235U value, the 7 most radiogenic Pb isotopic analyses for acid-leached pyroxene-rich and whole rock fractions yield an isochron Pb-Pb age of 4556.75 ± 0.57 Ma, in excellent agreement with the results of Mn-Cr chronology which give the ages of 4557.4 ± 2.5 Ma and 4555.9 ± 3.2 Ma using the U-corrected Pb-Pb age of D'Orbigny as a time anchor. Along with the previously proposed thermal history of Ibitira and our closure temperature estimates for Pb diffusion, the Pb-Pb age is interpreted as the timing of the last chemical equilibration and coarse pyroxene exsolution that occurred during high temperature metamorphism. The metamorphism may have been caused by burial of Ibitira lava under successive lava flows and, if so, the Pb-Pb age should post-date the crystallization by a short time interval. The Pb isotopic data for acid leachates suggest partial re-equilibration of Pb between plagioclase and phosphate, perhaps during an impact event at 4.49 Ga, as recorded by K-Ar systematics. The whole rock 238U/204Pb indicates that compared to CI chondrites, Ibitira is less depleted in Pb than in some alkali elements despite a lower condensation temperature of Pb than the alkali elements. The restricted Pb depletion may reflect preferential concentration of metals with high fluid/melt partition coefficients including Pb and Zn as a result of fluid exsolution and migration within the parent magma. We

  16. 76 FR 60112 - Culturally Significant Objects Imported for Exhibition Determinations: “Byzantium and Islam: Age...

    Science.gov (United States)

    2011-09-28

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Objects Imported for Exhibition Determinations: ``Byzantium and Islam: Age of... Islam: Age of Transition (7th-9th Century),'' imported from abroad for temporary exhibition within...

  17. Geomagnetic paleointensity and direct age determination of the ISEA (M0r?) chron

    Science.gov (United States)

    Zhu, Rixiang; Hoffman, Kenneth A.; Nomade, Sébastien; Renne, Paul R.; Shi, Ruiping; Pan, Yongxin; Shi, Guanghai

    2004-01-01

    A combined paleomagnetic and geochronologic study has been conducted on an andesite lava sequence at Jianguo (Liaoning province, northeastern China). Thermal demagnetization and thermomagnetic analysis revealed that natural remanent magnetization is carried by both magnetite and hematite. Stepwise thermal demagnetization up to 675°C isolated well-defined reverse characteristic remanent magnetization (ChRM) in three time-independent lava flows with a mean direction of D/ I=179.2°/-59.7° with α95=3.0°. It also showed that a high-temperature component (>585°C) has the same ChRM direction as that of the low- to medium-temperature (ca. 170/300-585°C) components. A modified version of the Thellier-Thellier paleointensity method [Coe, J. Geophys. Res. 72 (1967) 3247-3262] with systematic partial thermoremanent magnetization checks was used for paleointensity determinations. Twelve out of 39 samples yielded reliable results in the temperature interval of 170-550°C. Virtual dipole moment values range from 3.9 to 4.7×10 22 Am 2 with an average of 4.2±0.1×10 22 Am 2. 40Ar/ 39Ar age determination on one lava flow is 116.8±3.0 Myr (2σ error, relative to Fish Canyon sanidine: 28.02±0.28 Myr). The magnetic reversed polarity with well-defined age could correspond to the 'ISEA' within the older part of the Cretaceous normal superchron (CNS), but we cannot rule out the possibility that this reversal interval could also correspond to the M0r due to many ambiguities on previous published ages on ISEA and M0r intervals as well as the new monitor age correction we applied. It also suggests that a weak magnetic field nature already documented before the CNS extended at least into the very beginning of the CNS.

  18. Determination of Lead by Electrochemistry

    Institute of Scientific and Technical Information of China (English)

    HE YuFeng; ZHANG Zhang; MA YongJun; KANG JingWan

    2001-01-01

    @@ Lead is one of the poisonous trace element for human body. It is important to find a way for measuring content of lead. Deternination of lead by electrochemistry is one of a method[1]. In this paper, lead is determined by single-sweep polarography. The absorption behavior of meso-tetra (4-sulfonylphenyl) porphyrin (H2TPPS4) complex with lead ion has also been studied.In Na2B4O7-NaOH solution with pH=l 0.5, the reduction peaks of the ligand are P1 (Ep1=-0.38V), P2 (Ep2=-1.04V), which potentials are obtained vs. S.C.E. When lead ion has been added into above solution. The peak current of P1 and P2 decrease, and a new reduction peak P3 (Ep3=-1.10 V) appears. It shows that the TPPS4-Pb(Ⅱ) complex forms,and this method can be applied to study the complex.

  19. Determination of Lead by Electrochemistry

    Institute of Scientific and Technical Information of China (English)

    HE; YuFeng

    2001-01-01

    Lead is one of the poisonous trace element for human body. It is important to find a way for measuring content of lead. Deternination of lead by electrochemistry is one of a method[1]. In this paper, lead is determined by single-sweep polarography. The absorption behavior of meso-tetra (4-sulfonylphenyl) porphyrin (H2TPPS4) complex with lead ion has also been studied.In Na2B4O7-NaOH solution with pH=l 0.5, the reduction peaks of the ligand are P1 (Ep1=-0.38V), P2 (Ep2=-1.04V), which potentials are obtained vs. S.C.E. When lead ion has been added into above solution. The peak current of P1 and P2 decrease, and a new reduction peak P3 (Ep3=-1.10 V) appears. It shows that the TPPS4-Pb(Ⅱ) complex forms,and this method can be applied to study the complex.……

  20. A Raman "spectroscopic clock" for bloodstain age determination: the first week after deposition.

    Science.gov (United States)

    Doty, Kyle C; McLaughlin, Gregory; Lednev, Igor K

    2016-06-01

    Knowing the time since deposition (TSD) of an evidentiary bloodstain is highly desired in forensics, yet it can be extremely complicated to accurately determine in practice. Although there have been numerous attempts to solve this problem using a variety of different techniques, currently, no established, well-accepted method exists. Here, a Raman spectroscopic approach was developed for determining the age of bloodstains up to 1 week old. Raman spectroscopy, along with two-dimensional correlation spectroscopy (2D CoS) and statistical modeling, was used to analyze fresh bloodstains at ten time points under ambient conditions. The 2D CoS results indicate a high correlation between several Raman bands and the age of a bloodstain. A regression model was built to provide quantitative predictions of the TSD, with cross-validated root mean squared error and R (2) values of 0.13 and 0.97, respectively. It was determined that a "new" (1 h) bloodstain could be easily distinguished from older bloodstains, which is very important for forensic science in helping to establish the relevant association of multiple bloodstains. Additionally, all bloodstains were confirmatively identified as blood by comparing the experimentally measured spectra to multidimensional body fluid spectroscopic signatures of blood, saliva, semen, sweat, and vaginal fluid. These results demonstrate that Raman spectroscopy can be used as a nondestructive analytical tool for discriminating between bloodstains on the scale of hours to days. This approach shows promise for immediate practical use in the field to predict the TSD with a high degree of accuracy. Graphical Abstract Bloodstain aging over time illustrating naturally ocurring processes. PMID:27007735

  1. Uranium age determination - Separation and analysis of 230Th and 231Pa

    International Nuclear Information System (INIS)

    be of high chemical recovery and must afford large decontamination factors. In general, the age obtained from parent/daughter ratios refers to the last separation of the parent nuclide from its daughters, i.e. the last purification of the material. The accuracy of the obtained age therefore depends on the quality of the purification process and assumes that the material subsequently has not been contaminated. Obviously the availability of two analytical methods relying on both, independent parent/daughter pairs will therefore significantly increase the confidence in the experimental results. In this work we demonstrate analytical methods for the age determination of uranium samples using the parent/daughter relations 234U/230Th and 235U/231Pa. Thorium is separated from bulk uranium using extraction chromatography and subsequently quantified using □-spectrometry, thermal ionisation mass spectrometry (TIMS) and inductively coupled mass spectrometry (ICP-MS). Protactinium is separated by highly selective sorption of protactinium to silica gel followed by □-spectrometric quantification. The methods were tested and validated using uranium reference materials of different uranium enrichment and of known ages. The experimental results obtained with both methods were found to agree with the assumed ages of the reference materials within the combined uncertainty of the measurement. The analysis exploiting the parent/daughter pair 235U/231Pa exhibits a slightly larger combined uncertainty and bias than the thorium method but is found valuable in validating the experimental results by means of a second, independent analysis. (author)

  2. Late Pleistocene Panthera leo spelaea (Goldfuss, 1810 skeletons from the Czech Republic (central Europe; their pathological cranial features and injuries resulting from intraspecific fights, conflicts with hyenas, and attacks on cave bears

    Directory of Open Access Journals (Sweden)

    Diedrich C G

    2011-11-01

    Full Text Available The world’s first mounted "skeletons" of the Late Pleistocene Panthera leo spelaea (Goldfuss, 1810 from the Sloup Cave hyena and cave bear den in the Moravian Karst (Czech Republic, central Europe are compilations that have used bones from several different individuals. These skeletons are described and compared with the most complete known skeleton in Europe from a single individual, a lioness skeleton from the hyena den site at the Srbsko Chlum-Komín Cave in the Bohemian Karst (Czech Republic. Pathological features such as rib fractures and brain-case damage in these specimens, and also in other skulls from the Zoolithen Cave (Germany that were used for comparison, are indicative of intraspecific fights, fights with Ice Age spotted hyenas, and possibly also of fights with cave bears. In contrast, other skulls from the Perick and Zoolithen caves in Germany and the Urșilor Cave in Romania exhibit post mortem damage in the form of bites and fractures probably caused either by hyena scavenging or by lion cannibalism. In the Srbsko Chlum-Komín Cave a young and brain-damaged lioness appears to have died (or possibly been killed by hyenas within the hyena prey-storage den. In the cave bear dominated bone-rich Sloup and Zoolithen caves of central Europe it appears that lions may have actively hunted cave bears, mainly during their hibernation. Bears may have occasionally injured or even killed predating lions, but in contrast to hyenas, the bears were herbivorous and so did not feed on the lion carcasses. The articulated lion skeletons found in cave bear dens deep within caves scattered across Europe (such as those from the Sloup, Zoolithen and Urșilor caves can therefore now be explained as being the result of lions being killed during predation on cave bears, either by the cave bears defending themselves or as a result of interspecific fights.

  3. Characterization of cultural remains associated to a human skeleton found at the site HMS Swift (1770)

    Science.gov (United States)

    Maier, M. S.; Gómez, B. A.; Parera, S. D.; Elkin, D.; De Rosa, H.; Ciarlo, N. C.; Svoboda, H.

    2010-08-01

    Different types of materials found in association with a human skeleton found in an 18th century shipwreck in Patagonia (Argentina) were analyzed by means of OM, SEM-EDX, HPLC, and chemical analysis. Alizarin and purpurin, the main anthraquinones of the dye plant Rubia tinctorum L. (madder) were identified as the coloring matter of a red fabric attached to the skeleton. Metallographic and chemical analysis of one of the dome-shaped buttons associated to the human bones revealed that it was composed of a Pb-Sn-Cu alloy known as pewter. The results obtained support the hypothesis that the remains originally were part of a private marine uniform.

  4. New Rb-Sr age determinations on the Archaean basement of eastern Sierra Leone

    International Nuclear Information System (INIS)

    The Archaean basement of Sierra Leone is a typical example of granite-greenstone terrains found in ancient continental nuclei. Reconnaissance field mapping showed that the area can be subdivided into old gneiss, which predates the greenstone belts, and young granite which is later than the greenstone belts. New Rb-Sr whole-rock age determinations on two suites of old tonalitic gneiss yield ages of 2786 +- 49 Ma and 2770 +- 137 Ma, which either reflect the time of formation of the original tonalites or their metamorphism. Three new Rb-Sr whole-rock age determinations on young granites yield ages of 2786 +- 143 Ma, 2780 +- 79 Ma and 2770 +- 50 Ma, which are interpreted as the time of emplacement. The widespread occurrence of similar young granites, throughout the Archaean of West Africa, suggests that these results date a major event in the evolution of this segment of the crust. A published Pb-Pb age of the old gneiss and the new ages of the young granite bracket the age of the greenstone belts to 3000-2770 Ma. However, if the Rb-Sr ages of the old gneiss reported in this paper reflect the time of their formation, the age of the greenstone belts is tightly bracketed to ca. 2770 Ma. There is no isotopic evidence for rocks substantially older than 3000 Ma in the West African Archaean. (Auth.)

  5. Selenium determination by fluorimetric method

    International Nuclear Information System (INIS)

    A fluorimetric method to determine selenium both in vegetable samples and blood serum is developed. The method consists of a radioisotope 75Se initially in order to optimize the determination of analytical conditions. Three samples digestion processes and also some factors related to methodology is studied. The nitric-percloric digestion process for 40 samples and the analytical process is shown. (M.J.C.)

  6. Structure factor determination by electron diffraction

    International Nuclear Information System (INIS)

    A selection of methods for structure factor determination by electron diffraction is presented. Results obtained by the different methods are compared with regard to accuracies in structure determination

  7. Clinical significance of combined determination of serum BGP, PTH, CT in aged osteoporosis

    International Nuclear Information System (INIS)

    Using radioimmunoassay to determine serum BGP, PTH and CT, the author showed that there are various changes of level of BGP, PTH, CT with respect to osteoporosis of different etiology. It suggested that the combined determination has certain reference value in clinical diagnosis, disease staging and treatment of the aged osteoporosis

  8. Differences in late fetal death rates in association with determinants of small for gestational age fetuses: population based cohort study

    Science.gov (United States)

    Cnattingius, Sven; Haglund, Bengt; Kramer, Michael S

    1998-01-01

    Objective: To examine differences in late fetal death rates in association with determinants of small for gestational age fetuses. Design: Population based cohort study. Subjects: 1 026 249 pregnancies without congenital malformations. Setting: Sweden 1983-92. Main outcome measure: Late fetal death rate. Results: Depending on underlying determinants late fetal death rates were greatly increased in extremely small for gestational age fetuses (range 16 to 45 per 1000) compared with non-small for gestational age fetuses (1.4 to 4.6). In extremely small for gestational age fetuses late fetal death rates were increased from 31 per 1000 in mothers aged less than 35 years to 45 per 1000 in older mothers, and from 22 per 1000 in women <155 cm in height to 33 per 1000 in women ⩾175 cm tall. Late fetal death rates were also higher in extremely small for gestational age fetuses in singleton compared with twin pregnancies and in non-hypertensive pregnancies compared with pregnancies complicated by severe pre-eclampsia or other hypertensive disorders. Slightly higher late fetal death rates were observed in nulliparous compared with parous women and in non-smokers compared with smokers. Conclusions: Although the risk of late fetal death is greatly increased in fetuses that are extremely small for gestational age the risk is strongly modified by underlying determinants—for example, there is a lower risk of late fetal death in a small for gestational age fetus if the mother is of short stature, has a twin pregnancy, or has hypertension. Key messages Small for gestational age fetuses are at increased risk of late fetal death regardless of the underlying determinants The effect of birthweight ratio on risk of late fetal death is modified by underlying determinants, except maternal age Regardless of birthweight ratio the rates of late fetal death are higher among women aged 35 years or older compared with younger women In pregnancies of extremely small for gestational age

  9. Stable isotopic records of bleaching and endolithic algae blooms in the skeleton of the boulder forming coral Montastraea faveolata

    OpenAIRE

    Hartmann, A.C.; Carilli, J. E.; Norris, R. D.; Charles, C. D.; Deheyn, D. D.

    2010-01-01

    Within boulder forming corals, fixation of dissolved inorganic carbon is performed by symbiotic dinoflagellates within the coral tissue and, to a lesser extent, endolithic algae within the coral skeleton. Endolithic algae produce distinctive green bands in the coral skeleton, and their origin may be related to periods of coral bleaching due to complete loss of dinoflagellate symbionts or “paling” in which symbiont populations are patchily reduced in coral tissue. Stable carbon isotopes were a...

  10. 黄芩苷对肺炎支原体骨架蛋白质的影响%Effects of Baicalin on Mycoplasma Pneumoniae Skeleton Protein

    Institute of Scientific and Technical Information of China (English)

    李振宇; 张树明

    2013-01-01

    目的:通过给药前后,对肺炎支原体骨架蛋白的sds-PaGe电泳分析,探讨黄芩苷对肺炎支原体骨架蛋白质的影响。方法采用微量倍比稀释法确定黄芩苷Mic,利用 ccU法测定肺炎支原体生长曲线,通过sds-PaGe分析肺炎支原体骨架蛋白的变化。结果黄芩苷Mic为16ug/ml,接种105~106ccU/ml的支原体传代,72h后达峰值7.0×107ccU/ml,在黄芩苷干预下,支原体骨架蛋白条带减少,表达降低。结论黄芩苷能能降低肺炎支原体骨架蛋白的表达。%ABSTRCAT: Objective to investigate the effects of Baicalin on Mycoplasma pneumoniae skeleton protein, through sds-PaGe electrophoresis analysis before and after the treatment.Methods Baicalin Mic was determined by broth microdilution method.the growth curve of Mycoplasma pneumoniae was detimined by the color change unit(ccU ). changes of mycoplasma pneumoniae skeleton protein was analyzed by sds-PaGe electrophoresis analysis.Result Mic of Baicalin was 16ug/ml. Mycoplasma pneumoniae reached the peak of 7.0×107ccU/ml after 72h in the case of initial concentration of 105~106ccU/ml. under the baicalin intervention, Mycoplasma skeleton protein bands decreased and protein expression is reduced.Conlusion Baicalin can reduce the expression of Mycoplasma pneumoniae skeleton protein expression.

  11. Expression of genes for bone morphogenetic proteins BMP-2, BMP-4 and BMP-6 in various parts of the human skeleton

    Directory of Open Access Journals (Sweden)

    Włodarski Krzysztof

    2007-12-01

    Full Text Available Abstract Background Differences in duration of bone healing in various parts of the human skeleton are common experience for orthopaedic surgeons. The reason for these differences is not obvious and not clear. Methods In this paper we decided to measure by the use of real-time RT-PCR technique the level of expression of genes for some isoforms of bone morphogenetic proteins (BMPs, whose role is proven in bone formation, bone induction and bone turnover. Seven bone samples recovered from various parts of skeletons from six cadavers of young healthy men who died in traffic accidents were collected. Activity of genes for BMP-2, -4 and -6 was measured by the use of fluorescent SYBR Green I. Results It was found that expression of m-RNA for BMP-2 and BMP-4 is higher in trabecular bone in epiphyses of long bones, cranial flat bones and corpus mandibulae then in the compact bone of diaphyses of long bones. In all samples examined the expression of m-RNA for BMP-4 was higher than for BMP-2. Conclusion It was shown that m-RNA for BMP-6 is not expressed in the collected samples at all. It is postulated that differences in the level of activation of genes for BMPs is one of the important factors which determine the differences in duration of bone healing of various parts of the human skeleton.

  12. The utility of ultrasonographic bone age determination in detecting growth disturbances; a comparative study with the conventional radiographic technique

    International Nuclear Information System (INIS)

    To test whether the conventional radiographic technique in determining bone age abnormalities can be replaced by ultrasonography. A total of 54 Caucasian subjects up to 7 years of age with clinically suspected growth problems underwent left hand and wrist radiographic and ultrasonographic bone age estimations with the use of the Greulich-Pyle atlas. The ultrasonographic scans targeted the ossification centers in the radius and ulna distal epiphysis, carpal bones, epiphyses of the first and third metacarpals, and epiphysis of the middle phalanx, as described in previous reports. The degree of agreement between the two sets of data, as well as the accuracy of the ultrasonographic method in detecting radiographically suggested bone age abnormities, was examined. The mean chronological age, radiographic bone age, and ultrasonographic bone age (all in months) were 41.96 ± 22.25, 26.68 ± 14.08, and 26.71 ± 13.50 in 28 boys and 43.62 ± 24.63, 30.12 ± 17.69, and 31.27 ± 18.06 in 26 girls, respectively. According to the Bland-Altman plot there was high agreement between the results of the two methods with only three outliers. The deviations in bone age from the chronological age taken by the two techniques had the same sign in all patients. Supposing radiography to be the method of reference, the sensitivity, specificity, positive predictive value, and negative predictive value of sonography in detecting growth abnormalities were all 100 % in males and 90.9, 100, 100, and 93.8 %, respectively, in females. The conventional radiographic technique for determining bone age abnormalities could be replaced by ultrasonography. (orig.)

  13. The utility of ultrasonographic bone age determination in detecting growth disturbances; a comparative study with the conventional radiographic technique

    Energy Technology Data Exchange (ETDEWEB)

    Hajalioghli, Parisa; Tarzamni, Mohammad Kazem; Arami, Sara [Tabriz University of Medical Sciences, Department of Radiology, Imam Reza Teaching Hospital, Tabriz (Iran, Islamic Republic of); Fouladi, Daniel Fadaei [Tabriz University of Medical Sciences, Neurosciences Research Center, Tabriz (Iran, Islamic Republic of); Tabriz University of Medical Sciences, Imam Reza Teaching Hospital, Neurosciences Research Center, Tabriz (Iran, Islamic Republic of); Ghojazadeh, Morteza [Tabriz University of Medical Sciences, Department of Physiology, School of Medicine, Tabriz (Iran, Islamic Republic of)

    2015-09-15

    To test whether the conventional radiographic technique in determining bone age abnormalities can be replaced by ultrasonography. A total of 54 Caucasian subjects up to 7 years of age with clinically suspected growth problems underwent left hand and wrist radiographic and ultrasonographic bone age estimations with the use of the Greulich-Pyle atlas. The ultrasonographic scans targeted the ossification centers in the radius and ulna distal epiphysis, carpal bones, epiphyses of the first and third metacarpals, and epiphysis of the middle phalanx, as described in previous reports. The degree of agreement between the two sets of data, as well as the accuracy of the ultrasonographic method in detecting radiographically suggested bone age abnormities, was examined. The mean chronological age, radiographic bone age, and ultrasonographic bone age (all in months) were 41.96 ± 22.25, 26.68 ± 14.08, and 26.71 ± 13.50 in 28 boys and 43.62 ± 24.63, 30.12 ± 17.69, and 31.27 ± 18.06 in 26 girls, respectively. According to the Bland-Altman plot there was high agreement between the results of the two methods with only three outliers. The deviations in bone age from the chronological age taken by the two techniques had the same sign in all patients. Supposing radiography to be the method of reference, the sensitivity, specificity, positive predictive value, and negative predictive value of sonography in detecting growth abnormalities were all 100 % in males and 90.9, 100, 100, and 93.8 %, respectively, in females. The conventional radiographic technique for determining bone age abnormalities could be replaced by ultrasonography. (orig.)

  14. Duration and determinants of birth interval among women of child bearing age in Southern Ethiopia

    OpenAIRE

    Abera Mulumebet; Wondafrash Mekitie; Yohannes Samuel; Girma Eshetu

    2011-01-01

    Abstract Background Longer intervals between consecutive births decrease the number of children a woman can have. This results in beneficial effects on population size and on the health status of mothers and children. Therefore, understanding the practice of birth interval and its determinants is helpful to design evidence based strategies for interventions. The objective of this study was to determine duration and determinants of birth interval among women of child bearing age in Lemo distri...

  15. Age, introduction of solid feed and weaning are more important determinants of gut bacterial succession in piglets than breed and nursing mother as revealed by a reciprocal cross-fostering model.

    Science.gov (United States)

    Bian, Gaorui; Ma, Shouqing; Zhu, Zhigang; Su, Yong; Zoetendal, Erwin G; Mackie, Roderick; Liu, Junhua; Mu, Chunlong; Huang, Ruihua; Smidt, Hauke; Zhu, Weiyun

    2016-05-01

    A reciprocal cross-fostering model with an obese typical Chinese piglet breed and a lean Western breed was used to identify genetic and maternal effects on the acquisition and development gut bacteria from birth until after weaning. Pyrosequencing of 16S rRNA genes results revealed an age- and diet-dependent bacterial succession process in piglets. During the first 3 days after birth, the bacterial community was relatively simple and dominated by Firmicutes with 79% and 65% relative abundance for Meishan and Yorkshire piglets, respectively. During the suckling period until day 14, the piglet breed and the nursing mother lead to increasing differentiation of the fecal bacterial community, with specific bacteria taxa associated with breed, and others with the nursing sow most likely due to its milk composition. Although the effect of nursing mother and the breed were evident through the suckling period, the introduction of solid feed and subsequent weaning were the major events occurring that dominated succession of the gut microbiota in the early life of piglets. This piglet cross-fostering model is a useful tool for studying the effects of diet, host genetics and the environment on the development and acquisition of the gut microbiota and over longer studies the subsequent impact on growth, health and performance of pigs. PMID:26940746

  16. Genotype by sex and genotype by age interactions with sedentary behavior: the Portuguese Healthy Family Study.

    Directory of Open Access Journals (Sweden)

    Daniel M V Santos

    Full Text Available Sedentary behavior (SB expression and its underlying causal factors have been progressively studied, as it is a major determinant of decreased health quality. In the present study we applied Genotype x Age (GxAge and Genotype x Sex (GxSex interaction methods to determine if the phenotypic expression of different SB traits is influenced by an interaction between genetic architecture and both age and sex. A total of 1345 subjects, comprising 249 fathers, 327 mothers, 334 sons and 325 daughters, from 339 families of The Portuguese Healthy Family Study were included in the analysis. SB traits were assessed by means of a 3-d physical activity recall, the Baecke and IPAQ questionnaires. GxAge and GxSex interactions were analyzed using SOLAR 4.0 software. Sedentary behaviour heritability estimates were not always statistically significant (p>0.05 and ranged from 3% to 27%. The GxSex and GxAge interaction models were significantly better than the single polygenic models for TV (min/day, EEsed (kcal/day, personal computer (PC usage and physical activty (PA tertiles. The GxAge model is also significantly better than the polygenic model for Sed (min/day. For EEsed, PA tertiles, PC and Sed, the GxAge interaction was significant because the genetic correlation between SB environments was significantly different from 1. Further, PC and Sed variance heterogeneity among distinct ages were observed. The GxSex interaction was significant for EEsed due to genetic variance heterogeneity between genders and for PC due to a genetic correlation less than 1 across both sexes. Our results suggest that SB expression may be influenced by the interactions between genotype with both sex and age. Further, different sedentary behaviors seem to have distinct genetic architectures and are differentially affected by age and sex.

  17. Companions for ``Nessie'' in the Milky Way's Skeleton

    Science.gov (United States)

    Kohler, Susanna

    2015-12-01

    The recent discovery of a purported bone of the Milky Way, a dark cloud nicknamed Nessie, has provided us with new clues for mapping out the spiral structure of our galaxy. It turns out that Nessie may not be alone: a follow-up study has identified more bones, potentially making up a skeleton of the Milky Way that traces out the densest parts of its spiral arms.Inconvenient Vantage PointHow many spiral arms does the Milky Way have? Where are they located? What does the structure look like between the arms? It may seem surprising that these fundamental questions dont yet have clear answers. But because were stuck in the galaxys disk, were forced to piece together our understanding of the Milky Ways structure based primarily on measurements of position and radial velocity of structures within the galactic plane.The discovery of Nessie presents an intriguing new tool to identify the layout of the galaxy. Nessie is a very long, thin, infrared-dark filament that runs along the modeled position of the Scutum-Centaurus arm and is believed therefore to trace the structure of the arm. In a new study led by Catherine Zucker (University of Virginia, Harvard-Smithsonian Center for Astrophysics), the authors have searched for additional bones like Nessie, hoping to use them to map out the skeleton of the Milky Way.New Bones DiscoveredIn this map of radial velocity vs. galactic longitude, the bone candidates are indicated by the numbered points. The colored lines indicate the positions of two of the galactic spiral arms, according to various models. Click for a closer look! [Zucker et al. 2015]Zucker and collaborators began by using World Wide Telescope, a tool that facilitates visualization of multiple layers of data at a variety of scales, to search through Spitzer infrared data for additional structures like Nessie. Searching specifically along the predicted positions of galactic arms, they found 15 initial bone candidates.Next, the team obtained radial-velocity data for the

  18. Age Determination for 346 Nearby Stars in the Herschel DEBRIS Survey

    OpenAIRE

    Vican, Laura

    2012-01-01

    DEBRIS is a flux-limited survey of nearby stars (spectral types A-M) for evidence of debris disks with the Herschel Space Observatory. One goal of the survey is to determine disk incidence as a function of various stellar parameters. Understanding debris disk evolution depends on knowledge of the precise age of stars around which these debris disks are found. However, finding ages for field stars is notoriously difficult. Furthermore, in an unbiased sample like DEBRIS, one is working with sta...

  19. An analysis of vascular surgery in elderly patients to determine whether age affects treatment strategy.

    LENUS (Irish Health Repository)

    O'Brien, G

    2012-03-01

    The incidence of arterial disease increases with age. Increasing life expectancy in the western world will intensify demands on vascular surgeons with regard to increasing caseload, expanding patient selection criteria, and more complex and minimally-invasive treatment options. We analysed our arterial cases over the past 31 years (n = 6,144) and compared our methods of intervention and complication rates in the elderly population (>75) with the younger cohort, in order to determine whether age should influence our management strategies.

  20. Determination of radionuclides in samples of middle-aged and older human femurs

    International Nuclear Information System (INIS)

    The paper presents the studies of the presence of gamma isotopes and 90Sr in 19 middle-to old-aged human femur samples. The samples were taken up during routine orthopedic operations in 2012. The aim of the paper was determination of some radionuclides in human bones and estimation of radiation dose created by 90Sr and 90Y (in bones). The 137Cs, 40K, 226Ra, 228Th, 234Th and 210Pb isotopes were determined by gamma spectrometry. The above mentioned radionuclide contents were in the ranges: 137Cs (0.04–1.45); 40K (13–86); 226Ra (1–21.5); 228Th (1.4–40.2); 234Th (0.4–5.7); 210Pb (0.7–8.4) Bq/kg d.w. 90Sr was assayed based on radiometric measurement of ingrown 90Y. The 90Sr content was in the range 0.27–1.85 Bq/kg d.w. Measurements of concentration of 90Sr and 90Y in bones were used to estimation of health risk by calculation of radiation dose. Adsorbed doses ranged from 2.7· 10−7 to 1.9 · 10−6 Gy/y for 90Sr and from 1.2 · 10−6 to 8.3 · 10−7 Gy/y for 90Y. - Highlights: • The paper presents the studies of the presence of gamma isotopes and 90Sr in 19 human femur samples. • The 137Cs, 40K, 226Ra, 228Th, 234Th, 210Pb. isotopes were determined by the gamma spectrometry method. • The 90Sr content was determined by LSC method

  1. Distribution of 239Pu and 241Am in the human skeleton

    International Nuclear Information System (INIS)

    The 241Am and 239Pu distribution in the skeletons of two former nuclear workers has been measured. The skeletons of both individuals appear to be within normal limits for Caucasian men about 50 y old. Both had lower limb bones that were heavier than the age controls and Case I had upper-body bones that were lighter than the age control group. The distribution of americium in the skeleton of Case I, 25 years post exposure, indicated that a more rapid turnover of initially deposited americium on the bone surfaces of cancellous bone, as compared to that deposited on the bone surfaces of compact bone, had occurred. This resulted in a larger proportion of americium located in the compact bone of the extremities and a lesser quantity in the more cancellous bones of the vertebral column, pelvis and rib cage. A similar shift in the distribution of plutonium occurred in Case II in the 35 y since initial deposition, but at a slower rate than that for americium. The ratio of each actinide in the liver to that in the systemic system (liver content/systemic system content) was 0.065 and 0.436, for americium and plutonium, respectively, suggesting that a much more rapid turnover of americium in the liver, compared to plutonium, provided a much larger fraction of that nuclide for circulatory feedback to the remodeling skeletal system. 8 references, 3 tables

  2. Determination of residual boron in thermally treated controlled-porosity glasses, by colorimetry, spectrography and isotachophoresis

    International Nuclear Information System (INIS)

    Controlled-porosity glasses (CPGs) are often applied as sorbents in chromatography. Besides having high thermal, chemical and mechanical resistance they are characterized by a very narrow pore-size distribution and the choice of mean pore diameter and porosity covers a wide range. In spite of these advantages, their range of use in chromatography is restricted because of their strong adsorption properties, which are connected with the presence of residual boron atoms in the porous CPG skeleton. The boron concentration on the CPG surface can be increased by proper thermal treatment. When CPGs are heated in the range 400-8000 the residual boron atoms in the network diffuse from the bulk to the surface. The paper discusses the boron content in porous glasses of different mean pore diameters and the determination of the enrichment of boron on the GPG surface, by three independent methods: colorimetry, spectrography and isotachophoresis. (author)

  3. Age and season determine European rabbit habitat use in Mediterranean ecosystems

    Science.gov (United States)

    Rueda, Marta; Rebollo, Salvador; Bravo, Lucía Gálvez

    2008-11-01

    Knowledge about the factors determining habitat use is especially interesting for herbivores living under seasonal climates as they have to deal with food shortage during the drought season. In this context, different-aged individuals are expected to respond differently to seasonal variations because nutritional requirements and predation risk can vary with age. We investigated adult and juvenile European rabbit ( Oryctolagus cuniculus) habitat use in a Mediterranean ecosystem of central Spain, during spring, summer and winter. Relationships between adult and juvenile rabbit pellet abundances and 11 environmental variables related to food availability and refuge density were analysed by means of multiple regression, and evaluated using information theory to identify the set of models best supported by the data. Density of warren entrances was the more constant predictor of habitat use for juvenile rabbits in all the seasons. Herbaceous vegetation volume had a negative influence and was the strongest predictor for adult rabbit habitat use in spring and winter. In summer, green vegetation cover became the strongest positive habitat use predictor. These results suggest that adults prefer to forage in low volume swards ensuring a wide sensory range for the detection of approaching predators. However, the arrival of summer and its associated food depletion forces them to shift toward more open productive areas where green vegetation persists, but at the expense of higher predation risk. Seasonal variation induces minor changes in juvenile habitat use due to their strong dependence on warrens. Thus, our results show that rabbit habitat use is influenced by animal age and seasonal variations in resources.

  4. Validation of adult height prediction based on automated bone age determination in the Paris Longitudinal Study of healthy children

    International Nuclear Information System (INIS)

    An adult height prediction model based on automated determination of bone age was developed and validated in two studies from Zurich, Switzerland. Varied living conditions and genetic backgrounds might make the model less accurate. To validate the adult height prediction model on children from another geographical location. We included 51 boys and 58 girls from the Paris Longitudinal Study of children born 1953 to 1958. Radiographs were obtained once or twice a year in these children from birth to age 18. Bone age was determined using the BoneXpert method. Radiographs in children with bone age greater than 6 years were considered, in total 1,124 images. The root mean square deviation between the predicted and the observed adult height was 2.8 cm for boys in the bone age range 6-15 years and 3.1 cm for girls in the bone age range 6-13 years. The bias (the average signed difference) was zero, except for girls below bone age 12, where the predictions were 0.8 cm too low. The accuracy of the BoneXpert method in terms of root mean square error was as predicted by the model, i.e. in line with what was observed in the Zurich studies. (orig.)

  5. Validation of adult height prediction based on automated bone age determination in the Paris Longitudinal Study of healthy children

    Energy Technology Data Exchange (ETDEWEB)

    Martin, David D. [Tuebingen University Children' s Hospital, Tuebingen (Germany); Filderklinik, Filderstadt (Germany); Schittenhelm, Jan [Tuebingen University Children' s Hospital, Tuebingen (Germany); Thodberg, Hans Henrik [Visiana, Holte (Denmark)

    2016-02-15

    An adult height prediction model based on automated determination of bone age was developed and validated in two studies from Zurich, Switzerland. Varied living conditions and genetic backgrounds might make the model less accurate. To validate the adult height prediction model on children from another geographical location. We included 51 boys and 58 girls from the Paris Longitudinal Study of children born 1953 to 1958. Radiographs were obtained once or twice a year in these children from birth to age 18. Bone age was determined using the BoneXpert method. Radiographs in children with bone age greater than 6 years were considered, in total 1,124 images. The root mean square deviation between the predicted and the observed adult height was 2.8 cm for boys in the bone age range 6-15 years and 3.1 cm for girls in the bone age range 6-13 years. The bias (the average signed difference) was zero, except for girls below bone age 12, where the predictions were 0.8 cm too low. The accuracy of the BoneXpert method in terms of root mean square error was as predicted by the model, i.e. in line with what was observed in the Zurich studies. (orig.)

  6. Oxidative dearomatic approach towards the synthesis of erythrina skeleton: a formal synthesis of demethoxyerythratidinone

    OpenAIRE

    Pan, Zhi-Qiang; Liang, Ji-Xuan; Chen, Jing-Bo; Yang, Xiao-Dong; Zhang, Hong-Bin

    2011-01-01

    A concise synthetic route leading to highly functional erythrina alkaloid skeletons has been developed. The key process is an oxidative carbon-carbon coupling followed by a conjugated addition. Based on this new strategy, a formal synthesis of demethoxyerythratidinone was completed in only 6 steps from 4-aminophenol.

  7. Mukaiyama and Torgov Chemistry in the Synthesis of (D-homo) Steroid Skeletons

    NARCIS (Netherlands)

    Sarabèr, F.C.E.; Drach, S.V.; Baranovsky, A.; Charnikhova, T.; Pogrebnoi, S.; Jansen, B.J.M.; Groot, de Æ.

    2006-01-01

    Three new, short, and efficient procedures have been developed for syntheses of steroid and D-homo steroid skeletons by application of Mukaiyama and Torgov chemistry. An important element in the first and in the second route is a Mukaiyama-Michael reaction with transfer of the silyl group from the s

  8. Structure of Salvioccidentalin, a Diterpenoid with a Rearranged neo-Clerodane Skeleton from Salvia occidentalis

    Directory of Open Access Journals (Sweden)

    Jorge Cárdenas

    2011-10-01

    Full Text Available From the aerial parts of Salvia occidentalis (Labiatae a new diterpenoid with a rearranged neo-clerodane skeleton was isolated. This new compound was named salvioccidentalin and its structure was established by spectroscopic means. A probable biogenetic relationship with salvigenolide from S. fulgens and salvileucalin A and spiroleucantholide from Salvia leucantha is proposed.

  9. Structure of Salvioccidentalin, a Diterpenoid with a Rearranged neo-Clerodane Skeleton from Salvia occidentalis

    OpenAIRE

    Jorge Cárdenas; José Antonio Morales-Serna; Bernardo Antonio Frontana-Uribe; Manuel Salmón; Miguel Ángel Jaime-Vasconcelos

    2011-01-01

    From the aerial parts of Salvia occidentalis (Labiatae) a new diterpenoid with a rearranged neo-clerodane skeleton was isolated. This new compound was named salvioccidentalin and its structure was established by spectroscopic means. A probable biogenetic relationship with salvigenolide from S. fulgens and salvileucalin A and spiroleucantholide from Salvia leucantha is proposed.

  10. Effects of ocean acidification on the dissolution rates of reef-coral skeletons

    Directory of Open Access Journals (Sweden)

    Robert van Woesik

    2013-11-01

    Full Text Available Ocean acidification threatens the foundation of tropical coral reefs. This study investigated three aspects of ocean acidification: (i the rates at which perforate and imperforate coral-colony skeletons passively dissolve when pH is 7.8, which is predicted to occur globally by 2100, (ii the rates of passive dissolution of corals with respect to coral-colony surface areas, and (iii the comparative rates of a vertical reef-growth model, incorporating passive dissolution rates, and predicted sea-level rise. By 2100, when the ocean pH is expected to be 7.8, perforate Montipora coral skeletons will lose on average 15 kg CaCO3 m−2 y−1, which is approximately −10.5 mm of vertical reduction of reef framework per year. This rate of passive dissolution is higher than the average rate of reef growth over the last several millennia and suggests that reefs composed of perforate Montipora coral skeletons will have trouble keeping up with sea-level rise under ocean acidification. Reefs composed of primarily imperforate coral skeletons will not likely dissolve as rapidly, but our model shows they will also have trouble keeping up with sea-level rise by 2050.

  11. Mineral homeostasis and regulation of mineralization processes in the skeletons of sharks, rays and relatives (Elasmobranchii).

    Science.gov (United States)

    Dean, Mason N; Ekstrom, Laura; Monsonego-Ornan, Efrat; Ballantyne, Jim; Witten, P Eckhard; Riley, Cyrena; Habraken, Wouter; Omelon, Sidney

    2015-10-01

    Sharks, rays and other elasmobranch fishes are characterized by a skeletal type that is unique among living vertebrates, comprised predominantly of an unmineralized cartilage, covered by a thin outer layer of sub-millimeter, mineralized tiles called tesserae. The mineralized portion of the skeleton appears to grow only by apposition, adding material at the edges of each tessera; maintenance of non-mineralized joints between tesserae is therefore vital, with precise control of mineral deposition and inhibition at the many thousands of growth fronts in the skeleton. Yet, we have only scattered evidence as to how the elasmobranchs mineralize and grow their skeletons. In this review, we take an "environment to skeleton" approach, drawing together research from a vast range of perspectives to track calcium and phosphate from the typical elasmobranch habitats into and through the body, to their deposition at tesseral growth fronts. In the process, we discuss the available evidence for skeletal resorption capability, mineral homeostasis hormones, and nucleation inhibition mechanisms. We also outline relevant theories in crystal nucleation and typical errors in measurements of serum calcium and phosphate in the study of vertebrate biology. We assemble research that suggests consensus in some concepts in elasmobranch skeletal development, but also highlight the very large gaps in our knowledge, particularly in regards to endocrine functional networks and biomineralization mechanisms. In this way, we lay out frameworks for future directions in the study of elasmobranch skeletal biology with stronger and more comparative links to research in other disciplines and into other taxa. PMID:26546857

  12. For Aging Blacks, 'Golden Years' Often Marred by Disability

    Science.gov (United States)

    ... For Aging Blacks, 'Golden Years' Often Marred by Disability And black women appear to be hardest hit, ... white people to live their final years with disabilities. "In 2011, at age 65, whites could expect ...

  13. Births By Age of Mother, 1960-2013

    Data.gov (United States)

    U.S. Department of Health & Human Services — This dataset is for California live births by age of mother, for years 1960-2013. The live birth counts per age bracket represent the live births to California...

  14. Interaction between age and aerobic fitness in determining heart rate dynamics

    International Nuclear Information System (INIS)

    Heart rate variability (HRV) and phase-rectified signal averaging (PRSA) estimates of heart rate dynamics are diminished in older people compared with younger people. However, it is not fully elucidated whether these differences are related to age per se or to the concomitant influence of aerobic fitness. Aerobic fitness (peak oxygen uptake, gas exchange threshold, oxygen uptake kinetics, exercise economy) was assessed in 70 healthy adults (41 male) aged 18–57 years. Participants also underwent a 24 h, ambulatory ECG for the derivation of HRV and PRSA variables. HRV was most sensitive to age and aerobic fitness when measured during the morning period (6 am–12 pm). HRV and PRSA were both diminished with age and were higher in aerobically superior participants. The decline in HRV with age was predominantly attributable to age itself (33%), with aerobic fitness representing an additional modulating factor. The present study also provides tentative evidence that assessment of the influence of aerobic fitness should not rely on .VO2peak alone. These findings demonstrate that age per se is an important factor in determining HRV. However, given the clinical importance of diminished HRV and the immutable nature of aging, the potential significance of physical activity/training to enhance cardiac regulatory function should not be underestimated. (paper)

  15. DETERMINATION OF FOOT MEASUREMENTS OF GIRLS BETWEEN THE AGES OF 7?14 IN MANISA

    Directory of Open Access Journals (Sweden)

    Gurbuz GULUMSER

    Full Text Available Foot is a important organ that carries human weight during lifelong and gives him movement and balance ability. The discomfort on the foot efects body biomecanics and also other organs. Wearing proper shoe is needed to protect the foot health. Presently, there is no foot measures for Turkish people. The aim of the study was to determine foot measures of girls between the ages of 7-14. The measures from 800 students were taken in Manisa. The data were evaluated by using SPSS 10.0 statistical program on computer. As a result, foot sizes of Turkish girls were founded to be different from other races. [TAF Prev Med Bull 2004; 3(11.000: 271-279

  16. Assessment of Yeast Aging by Flow Cytometry

    Czech Academy of Sciences Publication Activity Database

    Baszczyňski, Martin; Kuřec, M.; Novák, Pavel; Brányik, Tomáš; Růžička, Marek; Drahoš, Jiří

    Bratislava : Slovak University of Technology, 2009 - (Markoš, J.), s. 317 ISBN 978-80-227-3072-3. [International Conference of Slovak Society of Chemical Engineering /36./. Tatranské Matliare (SK), 25.05.2009-29.05.2009] R&D Projects: GA ČR GA104/07/1110; GA ČR(CZ) GD104/08/H055; GA ČR GA104/06/1418 Institutional research plan: CEZ:AV0Z40720504 Keywords : yeast * aging * bud scars Subject RIV: CI - Industrial Chemistry, Chemical Engineering

  17. Late Bronze Age Hoard studied by PIXE

    OpenAIRE

    Gutiérrez Neira, P. C.; Zucchiatti, A.; Montero-Ruiz, I.; Vilaça, R.; Bottaini, C.; Gener, M.; Climent-Font, A.

    2011-01-01

    The hoards of metallic objects belonging to the Late European Bronze Age can be interpreted differently depending on the type, number and composition of the artefacts. PIXE analysis has been performed in nine items from the Hoard of Freixanda in Portugal comprising 4 socket axes, a palstave axe, a ring, a chisel, a dagger, and a casting debris. Besides the composition of the main matrix elements, that is Cu and Sn, the amount of trace elements of interest like, As, Pb, Ni and A...

  18. Persuasion Tactics Used by College Age Females on College Age Males.

    Science.gov (United States)

    Hanson, Erika J.; Pollard, Gloria D.; Williams, Christina M.

    This paper researched persuasive tactics used by college age females on college age males. Previous evidence indicates that nonverbal persuasion is more effective than verbal persuasion. The topics explored in previous research on persuasion consisted of physical attractiveness, indirect knowledge of influence, tactics used by children and college…

  19. Examining aging sexual stigma attitudes among adults by gender, age, and generational status

    OpenAIRE

    Syme, Maggie L.; Cohn, Tracy J.

    2015-01-01

    Objectives: Stigma related to later life sexuality could produce detrimental effects for older adults, through individual concerns and limited sexual health care for older adults. Identifying groups at risk for aging sexual stigma will help to focus interventions to reduce it. Accordingly, the purpose of this study was to examine cross-sectional trends in aging sexual stigma attitudes by age group, generational status, and gender.Method: An online survey was administered to a national sample ...

  20. Historic timber skeleton structures and the local seismic culture

    Science.gov (United States)

    Bostenaru, M.

    2009-04-01

    This presentation deals with the employment of timber skeleton structure and the local seismic culture. After the 1755 earthquake in the reconstruction of Lisbon a type of building with timber skeleton and masonry infill called "gaiola pombalina" was promoted, since this was designed to better resists earthquakes. "Gaiola" means cage, and it was also named after the Marques de Pombal who introduced it in the reconstruction following the earthquake. The „gaiola pombalina" presents a timber skeleton with Saint Andrew crosses in the interior walls with masonry infill and thick masonry load bearing walls loosing in thickness to the upper floors in the exterior walls. The masonry can fall out during earthquakes but the building remains staying given the interior timber skeleton. The type of buildings with timber structure and (masonry) infill behaved well in earthquakes in various parts of the earth, like Nepal (the dhaji dewary type), Pakistan, Turkey (the himiş type after the 1999 earthquake) [both latter types were researched by Langenbach, www.conservationtech.com and www.traditional-is-modern.net] and also in Germany after the 1356 earthquake (the Southern German subtype of Fachwerk). Also in Italy a subtype called "casa baraccata" was promoted in a construction code to a similar time (following the 1783 earthquake in Southern Italy, see Tobriner 1983) as that of the "gaiola pombalina", the time of the Baroque, when town planning acquired another status. Unlike at the "gaiola pombalina" the "casa baraccata" the timber skeleton is at the exterior walls. For this reason this type of buildings is considered to be an expression of the local seismic culture. However, this type of buildings is common also for areas where seismic risk is not an issue, like half-timbered in England and the northern subtype of Fachwerk in Northern Germany, and in some high seismic risk regions with mountains and timber resources like Romania is not spread. Given these premises the author

  1. Age estimation in the living

    DEFF Research Database (Denmark)

    Larsen, Sara Tangmose; Thevissen, Patrick; Lynnerup, Niels;

    2015-01-01

    A radiographic assessment of third molar development is essential for differentiating between juveniles and adolescents in forensic age estimations. As the developmental stages of third molars are highly correlated, age estimates based on a combination of a full set of third molar scores are...... statistically complicated. Transition analysis (TA) is a statistical method developed for estimating age at death in skeletons, which combines several correlated developmental traits into one age estimate including a 95% prediction interval. The aim of this study was to evaluate the performance of TA in the...... living on a full set of third molar scores. A cross sectional sample of 854 panoramic radiographs, homogenously distributed by sex and age (15.0-24.0 years), were randomly split in two; a reference sample for obtaining age estimates including a 95% prediction interval according to TA; and a validation...

  2. 13C-NMR of diterpenes with pimarane skeleton

    International Nuclear Information System (INIS)

    The effect of substituent groups on the chemical shift of carbons using nuclear magnetic resonance spectra of carbon 13 (13C-NMR) is discussed. Diterpenes having pimarane skeleton, isolated from plants of Velloziaceae family are analysed. (ARHC)

  3. Zebrafish Skeleton Measurements using Image Analysis and Machine Learning Methods

    OpenAIRE

    Stern, Olivier; Marée, Raphaël; Aceto, Jessica; Jeanray, Nathalie; Muller, Marc; Wehenkel, Louis; Geurts, Pierre

    2011-01-01

    The zebrafish is a model organism for biological studies on development and gene function. Our work aims at automating the detection of the cartilage skeleton and measuring several distances and angles to quantify its development following different experimental conditions.

  4. Method for determining the age of diesel oil spills in the soil

    International Nuclear Information System (INIS)

    This study evaluates the changes in the composition of diesel oil as a function of the time during which the oil has been present in the vadose zone. The study also develops a reliable method for determining the age of diesel oil in the subsurface soil environment at service stations, oil terminals, and similar locations where the diesel is protected from direct exposure to factors increasing the rate of microbial activity. Analyses demonstrate that n-alkanes are the dominant components of fresh oil and isoprenoids the dominant components of degraded diesel oil. The analyses also show that the composition of fresh diesel oil produced in 1992 and that produced in 1974 is basically the same. The difference in composition between fresh and degraded oil is te basis for defining a degradation ratio or rate of alteration in the composition of the diesel oil expressed in terms of a ratio between n-alkanes and isoprenoids. At 12 test locations where the date of property damage was known, the c17/pristane ratio had by far the highest correlation factor (.89) with the residence time of the diesel based on the average degradation ratio for each location. Based on this high correlation factor, the C17/pristane ratio can be used to estimate the age of a diesel oil spill. The standard error of such an estimate is approximately two years

  5. Determination of permanent premolars eruption ages among public school children in Lahore, Pakistan

    International Nuclear Information System (INIS)

    Objective: To determine mean eruption age, range and sequence of permanent maxillary and mandibular premolars in public schools of Lahore, Pakistan so as to provide a reference for planning orthodontic treatment and in pediatric dentistry. Methodology: This is a cross sectional study consisting of multistage random sampling and included 4000 children, with ages in between 9-14 years of different public schools in Lahore. Participants were examined and tooth numbering was noted by two-digit system of FDI (Federation Dentaire Internationale). Emergence was divided into three stages depending on eruption level. SPSS version 18 was used for statistical analysis. Results: Out of 4000 children, 1960 were boys and 2031 were girls. In both genders maxillary premolars erupted before mandibular counterparts. All premolars erupted earlier in females than the males. The sequence of emergence for both genders was P1, P2 in upper as well as in lower arch. Conclusion: Eruption of premolar in females was earlier than males but delayed in both genders while compared with Western standard. (author)

  6. Is Greulich–Pyle age estimation applicable for determining maturation in male Africans?

    Directory of Open Access Journals (Sweden)

    Alan G. Morri

    2012-09-01

    Full Text Available Skeletal age estimation as a means of assessing development and skeletal maturation in children and adolescents is of great importance for clinical and forensic purposes. The skeletal age of a test population is estimated by comparison with established standards, the most common standards being those in the Radiographic atlas of skeletal development of the hand and wristpublished by Greulich and Pyle in 1959. These standards are based on the assumption that skeletal maturity in male individuals is attained by the chronological age of 19 years. Although they have been widely tested, the applicability of these standards to contemporary populations has yet to be tested on a population of African biological origin living in South Africa. We therefore estimated the skeletal age of 131 male Africans aged between 13 and 21 years, using the Greulich–Pyle method which we applied to pre-existing hand–wrist radiographs. Estimated skeletal age was compared to the known chronological age for each radiograph. Skeletal age was on average approximately 6 months younger than chronological age. The Greulich–Pyle method underestimated skeletal age for approximately 74%of the sample and overestimated skeletal age for 26%of the sample. Skeletal maturity as characterised by complete epiphyseal fusion occurred approximately 2.1 years later than Greulich and Pyle’s estimate of 19 years. Thus skeletal maturation was still in progress in a large proportion of the 20- and 21-year-old individuals in our study. The Greulich–Pyle method showed high precision but low accuracy and was therefore not directly applicable to African male individuals. Formulation of skeletal age estimation standards specific to South African populations is therefore recommended.

  7. Oviraptorosaurian Eggs (Dinosauria) with Embryonic Skeletons Discovered for the First Time in China

    Institute of Scientific and Technical Information of China (English)

    Yen-nien CHENG; JI Qiang; Xiao-chun WU; Hsi-yin SHAN

    2008-01-01

    Two elongatoolithid dinosaur eggs from the Upper Cretaceous of Ganzhou, Jiangxi Province and the embryonic skeletons they bear are described. They represent the first Oviraptorosaurian eggs with embryonic skeletons in China and provide the first example that an oospecies can be correlated to certain dinosaur taxon/taxa. The two eggs are the same as the pair of the eggs inside a female Oviraptorosaurian pelvis from the same horizon of the same area in both macro- and micro-structures of the egg shells, and can be referred to the oospecies, Macroolithus yaotunensis Zhao, 1975. The morphology of the preserved part of the embryonic skeletons indicates that they may have been laid by an oviraptorid, Heyuannia huangi from Guangdong Province or a closely related Oviraptorosaurian, which may have been lived in the Ganzhou area too in the Late Cretaceous. The embryonic skeletons of the two eggs are not in the same developing stage. In one of the eggs, the postzygapophysis of the preserved vertebrae are well ossified, indicating that it was just hatched.

  8. Skeleton-based OPC application for DSA full chip mask correction

    Science.gov (United States)

    Schneider, L.; Farys, V.; Serret, E.; Fenouillet-Beranger, C.

    2015-09-01

    Recent industrial results around directed self-assembly (DSA) of block copolymers (BCP) have demonstrated the high potential of this technique [1-2]. The main advantage being cost reduction thanks to a reduced number of lithographic steps. Meanwhile, the associated correction for mask creation must account for the introduction of this new technique, maintaining a high level of accuracy and reliability. In order to create VIA (Vertical Interconnect Layer) layer, graphoepitaxy DSA can be used. The technique relies on the creation of a confinement guides where the BCP can separate into distinct regions and resulting patterns are etched in order to obtain an ordered series of VIA contact. The printing of the guiding pattern requires the use of classical lithography. Optical proximity correction (OPC) is applied to obtain the best suited guiding pattern allowing to match a specific design target. In this study, an original approach for DSA full chip mask optical proximity correction based on a skeleton representation of a guiding pattern is proposed. The cost function for an OPC process is based on minimizing the Central Placement Error (CPE), defined as the difference between an ideal skeleton target and a generated skeleton from a guiding contour. The high performance of this approach for DSA OPC full chip correction and its ability to minimize variability error on via placement is demonstrated and reinforced by the comparison with a rigorous model. Finally this Skeleton approach is highlighted as an appropriate tool for Design rules definition.

  9. Three-dimensional image technology in forensic anthropology: Assessing the validity of biological profiles derived from CT-3D images of the skeleton

    Science.gov (United States)

    Garcia de Leon Valenzuela, Maria Julia

    This project explores the reliability of building a biological profile for an unknown individual based on three-dimensional (3D) images of the individual's skeleton. 3D imaging technology has been widely researched for medical and engineering applications, and it is increasingly being used as a tool for anthropological inquiry. While the question of whether a biological profile can be derived from 3D images of a skeleton with the same accuracy as achieved when using dry bones has been explored, bigger sample sizes, a standardized scanning protocol and more interobserver error data are needed before 3D methods can become widely and confidently used in forensic anthropology. 3D images of Computed Tomography (CT) scans were obtained from 130 innominate bones from Boston University's skeletal collection (School of Medicine). For each bone, both 3D images and original bones were assessed using the Phenice and Suchey-Brooks methods. Statistical analysis was used to determine the agreement between 3D image assessment versus traditional assessment. A pool of six individuals with varying experience in the field of forensic anthropology scored a subsample (n = 20) to explore interobserver error. While a high agreement was found for age and sex estimation for specimens scored by the author, the interobserver study shows that observers found it difficult to apply standard methods to 3D images. Higher levels of experience did not result in higher agreement between observers, as would be expected. Thus, a need for training in 3D visualization before applying anthropological methods to 3D bones is suggested. Future research should explore interobserver error using a larger sample size in order to test the hypothesis that training in 3D visualization will result in a higher agreement between scores. The need for the development of a standard scanning protocol focusing on the optimization of 3D image resolution is highlighted. Applications for this research include the possibility

  10. Determination of adrenal volume by MRI in healthy children

    DEFF Research Database (Denmark)

    Mouritsen, Annette; Johansen, Marie Lindhardt; Wohlfahrt-Veje, Christine;

    2014-01-01

    BACKGROUND: Adrenal disorders such as congenital adrenal hyperplasia result in abnormal adrenal size and morphology, but little is known about the clinical value of magnetic resonance imaging (MRI) in determining adrenal volume. OBJECTIVE: To evaluate the potential usefulness of MR methodology, to...... estimate adrenal size in healthy children and to evaluate determinants of adrenal volume such as age, gender, body size, pubic hair stage and serum levels of adrenal androgens. DESIGN: Two hundred and thirty-five healthy children (116 girls and 119 boys) (age range 10.0-14.8 years) were examined by MRI...... (estimate B = 0.34 ml/year, P = 0.03), age (estimate B = 0.05 ml/year, P = 0.021) and pubic hair stage (estimate B = 0.05 ml/stage, P = 0.075). No associations between adrenal size and serum levels of adrenal androgens were observed. CONCLUSION: It was possible to determine adrenal volume by MRI in only 50...

  11. Burnup determination and age dating of spent nuclear fuel using noble gas isotopic analysis

    International Nuclear Information System (INIS)

    During the chopping and dissolving phases of reprocessing, gases (such as tritium, krypton, xenon, iodine, carbon dioxide, nitrogen oxide, and steam) are released. These gases are traditionally transferred to a gas-treatment system for treatment, release, and/or recycle. Because of their chemically inert nature, the xenon and krypton noble gases are generally released directly into the loser atmosphere through the facility's stack. These gases (being fission products) contain information about the fuel being reprocessed and may prove a valuable monitor of reprocessing activities. Two properties of the fuel that may prove valuable from a safeguards standpoint are the fuel burnup and the fuel age (or time since discharge from the reactor). Both can be used to aid in confirming declared activities, and the burnup is generally indicative of the usability of the fuel for fabricating nuclear explosives. A study has been ongoing at Los Alamos National Laboratory to develop a methodology to determine spent-fuel parameters from measured xenon and/or krypton isotopic ratios on-stack at reprocessing facilities. This study has resulted in the generation of the NOVA data analysis code, which links to a comprehensive database of reactor physics parameters (calculated using the Monteburns 3.01 code system). NOVA has been satisfactorily tested for burnup determination of weapons-grade fuel from a US production reactor. Less effort has been spent quantifying NOVA's ability to predict burnup and fuel age for power reactor fuel. The authors describe the results predicted by NOVA for xenon and krypton isotopic ratios measured after the dissolution of spent-fuel samples from the Borssele reactor. The Borssele reactor is a 450-MW(electric) pressurized water reactor (PWR) consisting of 15 x 15 KWU assemblies. The spent-fuel samples analyzed were single fuel rods removed from one assembly and dissolved at the La Hague reprocessing facility. The assembly average burnup was estimated at 32

  12. Regeneration of the aged thymus by a single transcription factor

    OpenAIRE

    Bredenkamp, N.; Nowell, C. S.; Blackburn, C C

    2014-01-01

    Thymic involution is central to the decline in immune system function that occurs with age. By regenerating the thymus, it may therefore be possible to improve the ability of the aged immune system to respond to novel antigens. Recently, diminished expression of the thymic epithelial cell (TEC)-specific transcription factor Forkhead box N1 (FOXN1) has been implicated as a component of the mechanism regulating age-related involution. The effects of upregulating FOXN1 function in the aged thymu...

  13. Loudness determined by power summation.

    Science.gov (United States)

    Howes, W. L.

    1971-01-01

    The predicted overall loudness of steady, broad-band noise is usually computed by summing weighted loudnesses of sub-bands of the noise intensity (mean-square pressure) spectrum. It is proposed, instead, that the overall loudness should be computed by summing weighted intensities of sub-bands ('critical bands') of noise and then obtaining the loudness of the sum. This method seems to yield better agreement with published loudness judgments than does the usual method. It appears that the proposed method should also yield better agreement with annoyance judgments than does the 'perceived noise' method of Kryter.

  14. Radioactivity determination by coincidence counting

    International Nuclear Information System (INIS)

    The 4 π β-γ coincidence counting equipment used in the Lucas Heights radioisotope standards laboratory for international comparisons is described in detail. A radioactivity standard is a method rather than a material object; as such it can be specified clearly only by discussing fully the setting-up and operation of one particular set of equipment. This manual is written for persons who are setting up such equipment for the first time

  15. ACOUSTIC STARTLE RESPONSE AFFECTED BY AGING AND CHOLINERGIC NEUROTRANSMITTERS

    Institute of Scientific and Technical Information of China (English)

    Anna Hansen; SUN Wei

    2014-01-01

    The acoustic startle response has been used to evaluate tinnitus and hyperacusis in animal models. Gap induced prepulse in-hibition of the acoustic startle reflex (gap-PPI) is affected by tinnitus and loudness changes. Since tinnitus and reduced sound tolerance are commonly seen in elderly, we measured gap-PPI in Fischer 344 rats, an aging related hearing loss model, at dif-ferent ages: 3-5 months, 9-12 months, and 15-17 months. The startle response was induced by three different intensity of sound:105, 95 and 85 dB SPL. Gap-PPI was induced by different duration of silent gaps from 1 to 100 ms. When the startle was induced by 105 dB SPL sound intensity, the gap-PPI induced by 50 ms silent gap was significantly lower than those in-duced by 25 or 100 ms duration, showing a“notch”in the gap-PPI function. The“notch”disappeared with the reduction of startle sound, suggesting the“notch”may be related with hyper-sensitivity to loud sound. As the intensity of the stimulus de-creased, the appearance of the hyperacusis-like effect decreased more quickly for the youngest group of rats. We also tested scopolamine, a muscarinic acetylcholine receptor antagonist, and mecamylamine, a nicotinic acetylcholine receptor antago-nist, on the effect of gap-PPI. When scopolamine was administered, the results indicated no addition effect on the hyperacu-sis-like phenomenon in the two older groups. Mecamylamine, the nicotinic antagonist also showed effects on the appearance of hyperacusis on rats in different ages. The information derived from the study will be fundamental for the further research in determining the cause and treatment for hyperacusis.

  16. Age dependence of natural uranium and thorium concentrations in bone.

    Science.gov (United States)

    Larivière, Dominic; Packer, Ana Paula; Marro, Leonora; Li, Chunsheng; Chen, Jing; Cornett, R Jack

    2007-02-01

    The age dependence of the natural concentration of uranium and thorium in the skeleton was investigated using human vertebrae bone collected from two Canadian locations (Winnipeg, Manitoba, and Regina, Saskatchewan). The concentration of both radioelements in digested ashed bone samples was determined using sector-field inductively coupled plasma mass spectrometry. The geometric means for uranium level in bones showed a significant statistical difference between the two locations studied. Similarly for thorium, a statistical difference was observed, although this difference was considered marginal. The thorium concentration differed only marginally with respect to age group, indicating that its behavior in the body could be age-independent. Conversely, the uranium level in bones was found to change for the age groups tested, an indication of age-specific deposition. The age profile for uranium was comparable to the calcium turn-over rate, indicating that uranium deposition is probably, in part, dictated by this metabolic process, showing the role of present uptake into the uranium concentration in bones for populations exposed to significant uranium intake. PMID:17220713

  17. Partial ages: diagnosing transport processes by means of multiple clocks

    Science.gov (United States)

    Mouchet, Anne; Cornaton, Fabien; Deleersnijder, Éric; Delhez, Éric J. M.

    2016-03-01

    The concept of age is widely used to quantify the transport rate of tracers - or pollutants - in the environment. The age focuses only on the time taken to reach a given location and disregards other aspects of the path followed by the tracer parcel. To keep track of the subregions visited by the tracer parcel along this path, partial ages are defined as the time spent in the different subregions. Partial ages can be computed in an Eulerian framework in much the same way as the usual age by extending the Constituent oriented Age and Residence Time theory (CART, www.climate.be/CARTocean are provided. They demonstrate the versatility of the concept of partial age and the potential new insights that can be gained with it.

  18. Determinants of Quality of Life in Ageing Populations: Results from a Cross-Sectional Study in Finland, Poland and Spain.

    Directory of Open Access Journals (Sweden)

    Alberto Raggi

    Full Text Available To comprehensively identify the determinants of quality of life (QoL in a population study sample of persons aged 18-50 and 50+.In this observational, cross-sectional study, QoL was measured with the WHOQOL-AGE, a brief instrument designed to measure QoL in older adults. Eight hierarchical regression models were performed to identify determinants of QoL. Variables were entered in the following order: Sociodemographic; Health Habits; Chronic Conditions; Health State description; Vision and Hearing; Social Networks; Built Environment. In the final model, significant variables were retained. The final model was re-run using data from the three countries separately.Complete data were available for 5639 participants, mean age 46.3 (SD 18.4. The final model accounted for 45% of QoL variation and the most relevant contribution was given by sociodemographic data (particularly age, education level and living in Finland: 17.9% explained QoL variation, chronic conditions (particularly depression: 4.6% and a wide and rich social network (4.6%. Other determinants were presence of disabling pain, learning difficulties and visual problems, and living in usable house that is perceived as non-risky. Some variables were specifically associated to QoL in single countries: age in Poland, alcohol consumption in Spain, angina in Finland, depression in Spain, and self-reported sadness both in Finland and Poland, but not in Spain. Other were commonly associated to QoL: smoking status, bodily aches, being emotionally affected by health problems, good social network and home characteristics.Our results highlight the importance of modifiable determinants of QoL, and provide public health indications that could support concrete actions at country level. In particular, smoking cessation, increasing the level of physical activity, improving social network ties and applying universal design approach to houses and environmental infrastructures could potentially increase QoL of

  19. Determinants of Quality of Life in Ageing Populations: Results from a Cross-Sectional Study in Finland, Poland and Spain

    Science.gov (United States)

    Corso, Barbara; Minicuci, Nadia; Quintas, Rui; Sattin, Davide; De Torres, Laura; Chatterji, Somnath; Frisoni, Giovanni Battista; Haro, Josep Maria; Koskinen, Seppo; Martinuzzi, Andrea; Miret, Marta; Tobiasz-Adamczyk, Beata; Leonardi, Matilde

    2016-01-01

    Purpose To comprehensively identify the determinants of quality of life (QoL) in a population study sample of persons aged 18–50 and 50+. Methods In this observational, cross-sectional study, QoL was measured with the WHOQOL-AGE, a brief instrument designed to measure QoL in older adults. Eight hierarchical regression models were performed to identify determinants of QoL. Variables were entered in the following order: Sociodemographic; Health Habits; Chronic Conditions; Health State description; Vision and Hearing; Social Networks; Built Environment. In the final model, significant variables were retained. The final model was re-run using data from the three countries separately. Results Complete data were available for 5639 participants, mean age 46.3 (SD 18.4). The final model accounted for 45% of QoL variation and the most relevant contribution was given by sociodemographic data (particularly age, education level and living in Finland: 17.9% explained QoL variation), chronic conditions (particularly depression: 4.6%) and a wide and rich social network (4.6%). Other determinants were presence of disabling pain, learning difficulties and visual problems, and living in usable house that is perceived as non-risky. Some variables were specifically associated to QoL in single countries: age in Poland, alcohol consumption in Spain, angina in Finland, depression in Spain, and self-reported sadness both in Finland and Poland, but not in Spain. Other were commonly associated to QoL: smoking status, bodily aches, being emotionally affected by health problems, good social network and home characteristics. Conclusions Our results highlight the importance of modifiable determinants of QoL, and provide public health indications that could support concrete actions at country level. In particular, smoking cessation, increasing the level of physical activity, improving social network ties and applying universal design approach to houses and environmental infrastructures could

  20. Selective arterial embolization of 36 aneurysmal bone cysts of the skeleton with N-2-butyl cyanoacrylate

    International Nuclear Information System (INIS)

    Aneurysmal bone cyst (ABC) is a lytic benign bone lesion representing about 1% of all primary bone tumors. The lesion causes pain and swelling, which are generally present for less than 3 months. From April 2003 to April 2008 36 patients affected by aneurysmal bone cysts were treated by selective arterial embolization with N-2-butyl cyanoacrylate. The study population comprised 20 male and 16 female patients with an age range of 3.3-60.8 years. Nine lesions were localized in the appendicular skeleton (1 in the upper and 8 in the lower limb), 4 in the thoracic cage (1 rib lesion and 3 scapular lesions), 17 in the pelvis and 6 in the spine (1 thoracic and 5 sacral localizations). A total of 55 embolizations were performed: in 22 cases (61%) only one embolization was needed, whilst two embolizations were necessary in 9 cases (25%) and 3 in the remaining 5 patients (14%). The treatment was effective in 32 patients (94%): follow-up was 0.9-5 years. In one patient, previously surgically treated, only the cyanoacrylate embolization turned out to be useful for healing the lesion. Another 7 patients underwent surgery during the study period. In the 55 procedures we performed we had 3 complications (5%): 2 cases of skin necrosis and 1 of transient paresis. Arterial embolization with cyanoacrylate may be the treatment of choice for aneurysmal bone cysts. Embolization is a less invasive, lower cost, simpler procedure than surgery and is easily repeatable. (orig.)

  1. Selective arterial embolization of 36 aneurysmal bone cysts of the skeleton with N-2-butyl cyanoacrylate

    Energy Technology Data Exchange (ETDEWEB)

    Rossi, Giuseppe [Rizzoli Orthopaedic Institute, Department of Interventional Angiographic Radiology, Bologna (Italy); Rimondi, Eugenio; Vanel, Daniel [Rizzoli Orthopaedic Institute, Department of Radiology, Bologna (Italy); Bartalena, Tommaso [University of Bologna, Bologna (Italy); Gerardi, Antonio [Rizzoli Orthopaedic Institute, Department of Anatomical Human Science and Physiopathology of the Musculoskeletal System, Bologna (Italy); Alberghini, Marco [Rizzoli Orthopaedic Institute, Department of Pathological Anatomy, Bologna (Italy); Staals, Eric Lodwijk; Errani, Costantino; Bianchi, Giuseppe; Toscano, Angelo; Mercuri, Mario [Rizzoli Orthopaedic Institute, V Division of Musculoskeletal Tumors, Bologna (Italy)

    2010-02-15

    Aneurysmal bone cyst (ABC) is a lytic benign bone lesion representing about 1% of all primary bone tumors. The lesion causes pain and swelling, which are generally present for less than 3 months. From April 2003 to April 2008 36 patients affected by aneurysmal bone cysts were treated by selective arterial embolization with N-2-butyl cyanoacrylate. The study population comprised 20 male and 16 female patients with an age range of 3.3-60.8 years. Nine lesions were localized in the appendicular skeleton (1 in the upper and 8 in the lower limb), 4 in the thoracic cage (1 rib lesion and 3 scapular lesions), 17 in the pelvis and 6 in the spine (1 thoracic and 5 sacral localizations). A total of 55 embolizations were performed: in 22 cases (61%) only one embolization was needed, whilst two embolizations were necessary in 9 cases (25%) and 3 in the remaining 5 patients (14%). The treatment was effective in 32 patients (94%): follow-up was 0.9-5 years. In one patient, previously surgically treated, only the cyanoacrylate embolization turned out to be useful for healing the lesion. Another 7 patients underwent surgery during the study period. In the 55 procedures we performed we had 3 complications (5%): 2 cases of skin necrosis and 1 of transient paresis. Arterial embolization with cyanoacrylate may be the treatment of choice for aneurysmal bone cysts. Embolization is a less invasive, lower cost, simpler procedure than surgery and is easily repeatable. (orig.)

  2. Determinants of willingness-to-pay for renewable energy: does the age of nuclear power plant reactors matter?

    OpenAIRE

    Mahieu, Pierre-Alexandre; Donfouet, Hermann Pythagore Pierre; Kriström, Bengt

    2014-01-01

    Many countries are facing a dilemma over whether to extend the lives of their old reactors or make costly capital investments on Renewable Energy (RE). This paper explores the determinants of Willingness-To-Pay (WTP) for RE in France by means of a contingent valuation question that was included in a large web survey organized by the OECD. The main contribution of our paper is to test whether people living close to a reactor are sensitive to the age of the reactor. We find that the age of the ...

  3. Effect of dietary, social, and lifestyle determinants of accelerated aging and its common clinical presentation: A survey study.

    Science.gov (United States)

    Samarakoon, S M S; Chandola, H M; Ravishankar, B

    2011-07-01

    Aging is unavoidable and natural phenomenon of life. Modern gerontologists are realizing the fact that aging is a disease, which Ayurveda had accepted as natural disease since long. Rate of aging is determined by one's biological, social, lifestyle, and psychological conditions and adversity of which leads to accelerated form of aging (Akalaja jara or premature aging). The aim of this study is to identify potential factors that may accelerate aging in the context of dietry factors, lifestyle and mental makeup. The 120 diagnosed subjects of premature-ageing of 30-60 years were randomly selected in the survey study. Premature ageing was common among females (75.83%), in 30-40 age group (70%), 86.67% were married, had secondary level of education (36.66%), house-views (61.67%), belongs top middle class (58.33%) and engaged in occupations that dominating physical labour (88.33%). The maximum patients are constipated (60%), had mandagni (80%), vata-kapha prakriti (48.33%), rajasika prakriti (58.33%), madhyama vyayama shakti (73.33%), and madhyama jarana shakti (85.83%). Collectively, 43.33% patients were above normal BMI. The more patients had anushna (38.33%) and vishamasana dietary pattern (25.83%), consumed Lavana (88.33%) and Amla rasa (78.33%) in excess on regular basis. Some patients had addicted to tobacco (11.67%) and beetle chewing (5.83%). The maximum patients had no any exercise (79.17%) and specific hobby (79.17%) in their leisure times. Analyzing Hamilton Anxiety and Depression Rating Scales revealed that 39.80%, 37.86%, 33.98%, 24.27% and 18.44% patients had insomnia, depression, tension, GIT symptoms and anxious mood respectively. These data suggest that certain social, dietary and lifestyle factors contribute towards accelerated ageing among young individuals. PMID:22529643

  4. Calcite formation in soft coral sclerites is determined by a single reactive extracellular protein.

    Science.gov (United States)

    Rahman, M Azizur; Oomori, Tamotsu; Wörheide, Gert

    2011-09-01

    Calcium carbonate exists in two main forms, calcite and aragonite, in the skeletons of marine organisms. The primary mineralogy of marine carbonates has changed over the history of the earth depending on the magnesium/calcium ratio in seawater during the periods of the so-called "calcite and aragonite seas." Organisms that prefer certain mineralogy appear to flourish when their preferred mineralogy is favored by seawater chemistry. However, this rule is not without exceptions. For example, some octocorals produce calcite despite living in an aragonite sea. Here, we address the unresolved question of how organisms such as soft corals are able to form calcitic skeletal elements in an aragonite sea. We show that an extracellular protein called ECMP-67 isolated from soft coral sclerites induces calcite formation in vitro even when the composition of the calcifying solution favors aragonite precipitation. Structural details of both the surface and the interior of single crystals generated upon interaction with ECMP-67 were analyzed with an apertureless-type near-field IR microscope with high spatial resolution. The results show that this protein is the main determining factor for driving the production of calcite instead of aragonite in the biocalcification process and that -OH, secondary structures (e.g. α-helices and amides), and other necessary chemical groups are distributed over the center of the calcite crystals. Using an atomic force microscope, we also explored how this extracellular protein significantly affects the molecular-scale kinetics of crystal formation. We anticipate that a more thorough investigation of the proteinaceous skeleton content of different calcite-producing marine organisms will reveal similar components that determine the mineralogy of the organisms. These findings have significant implications for future models of the crystal structure of calcite in nature. PMID:21768106

  5. Thermal consolidation of porous medium with a rheological kelvin-voigt skeleton

    Science.gov (United States)

    Bartlewska-Urban, Monika; Strzelecki, Tomasz

    2012-10-01

    This study presents calculations results of thermal consolidation process of the porous medium with the rheological Kelvin-Voigt skeleton, obtained numerically with the use of Flex.PDE software. The investigated calculation scheme consisted of the porous column filled with a liquid. The vertical load was applied to the top surface of the column through a porous plate allowing the free flow of liquid through this surface. Numerical solution is based on compression of the sample at appropriately defined boundary conditions. The aim of this study was to describe the influence of external load and temperature gradient on the deformation tests progress at different values of three parameters: λ, rs and cv. The results obtained, in the context of further research, can also be used for the determination of the influence of other parameters of the state and model parameters on the process of thermo poroelasticity of Biot model with rheological skeleton.

  6. What determines age-related disease: do we know all the right questions?

    Science.gov (United States)

    Juckett, David A

    2010-06-01

    The average human lifespan has increased throughout the last century due to the mitigation of many infectious diseases. More people now die of age-related diseases than ever before, but these diseases have been resistant to elimination. Progress has been made in treatments and preventative measures to delay the onsets of these diseases, but most cancers and vascular diseases are still with us and they kill about the same fraction of the population year after year. For example, US Caucasian female deaths from breast plus genital cancers have remained a fairly constant approximately 7% of the age-related disease deaths from 1938 to 1998 and have been consistently approximately 2-fold greater than female colon plus rectal cancer deaths over that span. This type of stability pattern pervades the age-related diseases and suggests that intrinsic properties within populations determine these fractions. Recognizing this pattern and deciphering its origin will be necessary for the complete understanding of these major causes of death. It would appear that more than the random processes of aging drive this effect. The question is how to meaningfully approach this problem. This commentary discusses the epidemiological and aging perspectives and their current limitations in providing an explanation. The age of bioinformatics offers hope, but only if creative systems approaches are forthcoming. PMID:19904627

  7. [Sonographic diagnosis of pregnancy and determination of fetal number and gestational age in ewes].

    Science.gov (United States)

    Schmid, D; Schiess, A; Tustain, G; Fleisch, A; Bollwein, H; Janett, F

    2016-02-01

    The aim of the present study was to evaluate accuracy of transabdominal ultrasonography for pregnancy diagnosis, determination of fetal number and estimation of gestational age in ewes. A total of 1068 ewes from 8 different flocks (Swiss White Alpine n = 379, Swiss Black-Brown Mountain n = 189, Oxford-type n = 164, Ostfriesian n = 154, Texel n = 104, Lacaune x Osfriesian crossbred n = 78) was investigated using an Ovi-Scan™ ultrasound scanner with a 3.5 MHz 170° mechanical axial probe (BCF Technology Ltd., BelIshill, Great Britain). Scanning was performed transabdominally at the right inguinal region in ewes restrained in standing position. Sonographic findings were compared with lambing data recorded by the farmers. Included in the analysis were all ewes that, at the time of examination, were not pregnant and those that were pregnant between 26 and 110 days with a known lambing date and number of lambs born (n = 882). The sensitivity of pregnancy diagnosis was 97.8% and the specificity 97.6% (overall accuracy 97.8%, n = 853). Sensitivity and specificity for discrimination between single and multiple pregnancies was 95.8% and 90.5% (overall accuracy 93.9%, n = 752), respectively, when multiples were defined as positive. Discrimination between twins and triplets reached a sensitivity of 86.0% and a specificity of 99.5% (overall accuracy 98.0%, n = 458) when triplets were defined as positive. Considering a gestation period of 150 days, the mean deviation of the estimated to the effective day of gestation at examination was 5.6 ± 5.0 days (n = 781). The correlation between estimated and true gestational age was very high (r=0.936, Page is possible using an Ovi-Scan™ ultrasound scanner by an experienced examiner. PMID:27145684

  8. Exclusive breastfeeding duration and determinants among Brazilian children under two years of age

    Directory of Open Access Journals (Sweden)

    Sarah Warkentin

    2013-06-01

    Full Text Available OBJECTIVE: The present study described the duration and identified the determinants of exclusive breastfeeding. METHODS: The study used data from the Pesquisa Nacional de Demografia e Saúde da Criança e da Mulher 2006 (National Demographic and Health Survey on Women and Children 2006. Data were collected using questionnaires administered by trained professionals and refer to a subsample of 1,704 children aged less than 24 months. The estimated durations of exclusive breastfeeding are presented according to socioeconomic, demographic and epidemiological variables. Kaplan Meier estimator curves were used to produce valid estimates of breastfeeding duration and the Cox's proportional hazards model was fitted to identify risks. RESULTS: The median estimated duration of exclusive breastfeeding was 60 days. The final Cox model consisted of mother's age <20 years (hazard ratio=1.53, 95% confidence interval=1.11-1.48, use of pacifier (hazard ratio=1.53, 95% confidence interval=1.37-1.71, not residing in the country's southeast region (hazard ratio=1.22, 95% confidence interval=1.07-1.40 and socioeconomic status (hazard ratio=1.28, 95% confidence interval=1.06-1.55. CONCLUSION: The Kaplan Meier estimator corrected the underestimated duration of breastfeeding in the country when calculated by the current status methodology. Despite the national efforts done in the last decades to promote breastfeeding, the results indicate that the duration of exclusive breastfeeding is still half of that recommended for this dietary practice to promote health. Ways to revert this situation would be ongoing educational activities involving the educational and health systems, associated with advertising campaigns on television and radio mainly targeting young mothers with low education level and low income, identified as those at high risk of weaning their children early.

  9. A comparison of the regeneration kinetics of radiation damage to mouse bone marrow in some skeleton regions

    International Nuclear Information System (INIS)

    The method of monitoring numbers of nucleated cells of the bone marrow in some skeleton regions was employed to determine the extent of radiation damage after whole-body irradiation of mice with 60Co-gamma rays in doses of 5, 7 and 9 Gy, and the regeneration kinetics of this radiation damage at intervals of 4, 6, 8 and 10 days post irradiation. The cellularity values found were expressed as per cents of control values of the respective bone marrow regions. The regeneration kinetics of radiation damage to hematopoietic tissue of the bone marrow was found to differ in the respective skeleton regions. (author)

  10. Ascertaining year of birth/age at death in forensic cases: A review of conventional methods and methods allowing for absolute chronology

    DEFF Research Database (Denmark)

    Lynnerup, Niels; Kjeldsen, H; Zweihoff, R;

    2010-01-01

    birth) is often a fundamental piece of data in connection with forensic identification of unidentified bodies. The methods most often used are based on determining various morphological, age-related, changes on the skeleton (or teeth, although odontological methods are not reviewed in this paper). As...

  11. Basic properties of 3D cast skeleton structures

    Directory of Open Access Journals (Sweden)

    M. Cholewa

    2011-12-01

    Full Text Available Purpose: of this paper is to present recent achievements in field of skeleton structures. The aim of this work is to show results of searching for mechanically and technologically advantageous micro- and macrostructures. Methods of microstructure controlling were described. Most important parameters of the manufacturing process were identified.Design/methodology/approach: The influence of internal topology to stress distribution was described with the use of computer simulations. Simulations of the mold filling processes were also carried out. Real experiments were performed to prove the simulation results. The Qualitative and quantitative metallographic analysis were also carried out.Findings: It was found that the octahedron shape of internal cell causes best stress distribution and that the skeleton castings are a good alternative for cellular materials such as metal foams, lattice structures and sandwich panels. Their structured arranged topology allows precise design of properties.Research limitations/implications: Casting methods used to manufacture materials such as described skeleton castings confirmed their usefulness. Not well known and used yet rheological properties of liquid metals allow obtaining shape complicated structures near to metallic foams but structured arranged.Practical implications: Technological parameters of the skeleton castings manufacturing process were developed. Without use of advanced techniques there is a possibility to manufacture cheap skeleton structures in a typical foundry. With use of advanced technology like 3D printing there are almost unlimited possibilities of the skeleton castings internal topologies.Originality/value: Three dimensional cast skeleton structures with internal topology of octahedron confirmed their usefulness as elements used for energy dissipation. Obtaining the homogenous microstructure in the whole volume of complicated shape castings can be achieved.

  12. Aging.

    Science.gov (United States)

    Park, Dong Choon; Yeo, Seung Geun

    2013-09-01

    Aging is initiated based on genetic and environmental factors that operate from the time of birth of organisms. Aging induces physiological phenomena such as reduction of cell counts, deterioration of tissue proteins, tissue atrophy, a decrease of the metabolic rate, reduction of body fluids, and calcium metabolism abnormalities, with final progression onto pathological aging. Despite the efforts from many researchers, the progression and the mechanisms of aging are not clearly understood yet. Therefore, the authors would like to introduce several theories which have gained attentions among the published theories up to date; genetic program theory, wear-and-tear theory, telomere theory, endocrine theory, DNA damage hypothesis, error catastrophe theory, the rate of living theory, mitochondrial theory, and free radical theory. Although there have been many studies that have tried to prevent aging and prolong life, here we introduce a couple of theories which have been proven more or less; food, exercise, and diet restriction. PMID:24653904

  13. 3D Skeleton model derived from Kinect Depth Sensor Camera and its application to walking style quality evaluations

    Directory of Open Access Journals (Sweden)

    Kohei Arai

    2013-07-01

    Full Text Available Feature extraction for gait recognition has been created widely. The ancestor for this task is divided into two parts, model based and free-model based. Model-based approaches obtain a set of static or dynamic skeleton parameters via modeling or tracking body components such as limbs, legs, arms and thighs. Model-free approaches focus on shapes of silhouettes or the entire movement of physical bodies. Model-free approaches are insensitive to the quality of silhouettes. Its advantage is a low computational costs comparing to model-based approaches. However, they are usually not robust to viewpoints and scale. Imaging technology also developed quickly this decades. Motion capture (mocap device integrated with motion sensor has an expensive price and can only be owned by big animation studio. Fortunately now already existed Kinect camera equipped with depth sensor image in the market with very low price compare to any mocap device. Of course the accuracy not as good as the expensive one, but using some preprocessing we can remove the jittery and noisy in the 3D skeleton points. Our proposed method is part of model based feature extraction and we call it 3D Skeleton model. 3D skeleton model for extracting gait itself is a new model style considering all the previous model is using 2D skeleton model. The advantages itself is getting accurate coordinate of 3D point for each skeleton model rather than only 2D point. We use Kinect to get the depth data. We use Ipisoft mocap software to extract 3d skeleton model from Kinect video. From the experimental results shows 86.36% correctly classified instances using SVM.

  14. Age determination methods in harbour seals (Phoca vitulina with a review of methods applicable to carnivores

    Directory of Open Access Journals (Sweden)

    Christina Lockyer

    2010-09-01

    Full Text Available The development of age determination methods in marine mammals is reviewed with particular reference to the use of teeth Growth Layer Groups (GLGs formed in the dentine and cement of carnivores. Using this background, practices for sampling, tooth extraction and collection, storage and different methods of preparation of teeth as well as reading and counting GLGs are discussed and evaluated for the harbour seal (Phoca vitulina. The paper includes comments on best practices for counting GLGs with new examples from known-age seals, and also a detailed examination of confounding factors in interpreting GLGs such as mineralization anomalies and the phenomena of accessory lines, “false annuli” and “paired laminae” which have not been discussed previously. The paper concludes with recommendations for undertaking age estimation in harbour seals from sampling through final GLG interpretation with special emphasis on standardization of methods with other researchers.

  15. Determining Remaining Useful Life of Aging Cables in Nuclear Power Plants - Interim Study FY13

    International Nuclear Information System (INIS)

    The most important criterion for cable performance is its ability to withstand a design-basis accident. With nearly 1000 km of power, control, instrumentation, and other cables typically found in an NPP, it would be a significant undertaking to inspect all of the cables. Degradation of the cable jacket, electrical insulation, and other cable components is a key issue that is likely to affect the ability of the currently installed cables to operate safely and reliably for another 20 to 40 years beyond the initial operating life. The development of one or more nondestructive evaluation (NDE) techniques and supporting models that could assist in determining the remaining life expectancy of cables or their current degradation state would be of significant interest. The ability to nondestructively determine material and electrical properties of cable jackets and insulation without disturbing the cables or connections has been deemed essential. Currently, the only technique accepted by industry to measure cable elasticity (the gold standard for determining cable insulation degradation) is the indentation measurement. All other NDE techniques are used to find flaws in the cable and do not provide information to determine the current health or life expectancy. There is no single NDE technique that can satisfy all of the requirements needed for making a life-expectancy determination, but a wide range of methods have been evaluated for use in NPPs as part of a continuous evaluation program. The commonly used methods are indentation and visual inspection, but these are only suitable for easily accessible cables. Several NDE methodologies using electrical techniques are in use today for flaw detection but there are none that can predict the life of a cable. There are, however, several physical and chemical ptoperty changes in cable insulation as a result of thermal and radiation damage. In principle, these properties may be targets for advanced NDE methods to provide early

  16. Determining Remaining Useful Life of Aging Cables in Nuclear Power Plants – Interim Study FY13

    Energy Technology Data Exchange (ETDEWEB)

    Simmons, Kevin L.; Fifield, Leonard S.; Westman, Matthew P.; Ramuhalli, Pradeep; Pardini, Allan F.; Tedeschi, Jonathan R.; Jones, Anthony M.

    2013-09-27

    The most important criterion for cable performance is its ability to withstand a design-basis accident. With nearly 1000 km of power, control, instrumentation, and other cables typically found in an NPP, it would be a significant undertaking to inspect all of the cables. Degradation of the cable jacket, electrical insulation, and other cable components is a key issue that is likely to affect the ability of the currently installed cables to operate safely and reliably for another 20 to 40 years beyond the initial operating life. The development of one or more nondestructive evaluation (NDE) techniques and supporting models that could assist in determining the remaining life expectancy of cables or their current degradation state would be of significant interest. The ability to nondestructively determine material and electrical properties of cable jackets and insulation without disturbing the cables or connections has been deemed essential. Currently, the only technique accepted by industry to measure cable elasticity (the gold standard for determining cable insulation degradation) is the indentation measurement. All other NDE techniques are used to find flaws in the cable and do not provide information to determine the current health or life expectancy. There is no single NDE technique that can satisfy all of the requirements needed for making a life-expectancy determination, but a wide range of methods have been evaluated for use in NPPs as part of a continuous evaluation program. The commonly used methods are indentation and visual inspection, but these are only suitable for easily accessible cables. Several NDE methodologies using electrical techniques are in use today for flaw detection but there are none that can predict the life of a cable. There are, however, several physical and chemical ptoperty changes in cable insulation as a result of thermal and radiation damage. In principle, these properties may be targets for advanced NDE methods to provide early

  17. Taking into account of the aging and the damage in the size determination of composite materials structures

    International Nuclear Information System (INIS)

    The aim of this study was to better understand the aging of glass fibres-epoxy composites exposed to humid conditions and loading so as to predict its effects on the lifetimes of composite structures. Water diffusion was first experimentally investigated by gravimetric method to determine water sorption kinetics for different humid conditions. A Fickian model of diffusion could describe the results obtained. Specimens, saturated at different levels, were mechanically characterised. Decreases of mechanical properties as a function of water uptake were revealed by tensile tests. Damage by cracking and the coupling with humidity were then studied. Differences between reversible and irreversible changes in properties were revealed and analysed in detail. A predictive model taking into account effects due to water and/or mechanical loading is proposed, using finite element method. As a first step, in modelling the diffusion process, the non-uniform water distribution across the composite are determined for any conditions (temperature, humidity, aging time). The resulting mechanical properties of the material, as a function of the absorbed water concentration, are determined in each point. Then, diffusion/mechanic coupled calculation allows to determine material global properties from properties at each point. It is then possible to predict continuous evolution of rigidity during aging time, at all stages of water absorption and matrix cracking, for any condition (temperature, humidity, thickness, mechanical loading level). (author)

  18. An evaluation of the precision of fin ray, otolith, and scale age determinations for brook trout

    Science.gov (United States)

    Stolarski, J.T.; Hartman, K.J.

    2008-01-01

    The ages of brook trout Salvelinus fontinalis are typically estimated using scales despite a lack of research documenting the effectiveness of this technique. The use of scales is often preferred because it is nonlethal and is believed to require less effort than alternative methods. To evaluate the relative effectiveness of different age estimation methodologies for brook trout, we measured the precision and processing times of scale, sagittal otolith, and pectoral fin ray age estimation techniques. Three independent readers, age bias plots, coefficients of variation (CV = 100 x SD/mean), and percent agreement (PA) were used to measure within-reader, among-structure bias and within-structure, among-reader precision. Bias was generally minimal; however, the age estimates derived from scales tended to be lower than those derived from otoliths within older (age > 2) cohorts. Otolith, fin ray, and scale age estimates were within 1 year of each other for 95% of the comparisons. The measures of precision for scales (CV = 6.59; PA = 82.30) and otoliths (CV = 7.45; PA = 81.48) suggest higher agreement between these structures than with fin rays (CV = 11.30; PA = 65.84). The mean per-sample processing times were lower for scale (13.88 min) and otolith techniques (12.23 min) than for fin ray techniques (22.68 min). The comparable processing times of scales and otoliths contradict popular belief and are probably a result of the high proportion of regenerated scales within samples and the ability to infer age from whole (as opposed to sectioned) otoliths. This research suggests that while scales produce age estimates rivaling those of otoliths for younger (age > 3) cohorts, they may be biased within older cohorts and therefore should be used with caution. ?? Copyright by the American Fisheries Society 2008.

  19. Spinal arthritis and physical stress at Bronze Age Harappa.

    Science.gov (United States)

    Lovell, N C

    1994-02-01

    This study examines joint changes in the vertebral skeleton in human remains excavated in 1987 and 1988 at Bronze Age Harappa, an urban center of the Indus Valley civilization. The sample consists of 23 complete skeletons from primary burial context, the partial remains of more than 69 other individuals, and hundreds of skeletal elements from secondary context, totalling 3,084 vertebral joint margins and articular surfaces. Marginal bone proliferation, pitting of articular surfaces, eburnation, and ankylosis were scored macroscopically for vertebral body margins and surfaces and posterior apophyseal facet joints. Marginal lipping is far more prevalent on the vertebral bodies than on the apophyseal facets and surface pitting is also more frequent on vertebral bodies although its expression is relatively low overall. Cervical vertebrae in this sample exhibit the same amount of marginal new bone and much more surface pitting of the vertebral bodies than do either thoracic or lumbar vertebrae; the cervical segment also exhibits the most severe expressions of both types of lesions. In addition, although the frequencies of cervical and lumbar posterior facet involvement are similar, the cervical facets exhibit much more severe lipping as well as the only cases of eburnation and ankylosis. Pitting of the posterior facets is most common in the lumbar segment, but the cervical examples are the only severe cases. It is proposed that the severe joint changes in the cervical spine result from trauma, perhaps accumulated microtrauma from activity stresses. There are no age or sex associated patterns in the frequency of arthritis although this result may be influenced by the small proportions of the total sample for which age and sex could be determined. PMID:8147433

  20. The influence of age on the relationships between SMEs growth and its determinants: empirical evidence using Panel Data

    OpenAIRE

    Gonçalves, Marco Xavier Badalo Mourato

    2010-01-01

    Using two sub-samples of Portuguese SMEs: 1) 495 young SMEs; and 2) 1350 old SMEs, through the two-step estimation method, we examine if age is a fundamental characteristic of the relationships established between determinants and SME growth. The multiple empirical evidence allows us to conclude that age is a determinant for the relationships formed between determinants and SME growth: 1) age and size are negatively related to growth in young SMEs, but are not relevant in explaini...

  1. Determining the age and history of plutonium using isotope correlations and experimentally determined data on isotopic abundances of plutonium and 241Am

    International Nuclear Information System (INIS)

    Linear correlations using a data set of nominally cooled samples of Pu formed in Indian PHWRs using experimentally determined 241Pu/239Pu versus 240Pu/239Pu and 241Am/239Pu versus 240Pu/239Pu isotope ratios have been developed which can be used for determining the age of Pu. By correlating both Pu and Am isotopic information, an understanding of how the material was processed, when chemical separations occurred to remove 241Am as well as the true age of the Pu in sample can be obtained. Two actual samples from a PHWR with unknown origin were analyzed as a part of case study for application of this new methodology. (author)

  2. Recent Advances in Imaging of the Axial Skeleton in Spondyloarthritis for Diagnosis, Assessment of Treatment Effect, and Prognostication

    DEFF Research Database (Denmark)

    Pedersen, Susanne Juhl; Maksymowych, Walter P

    2015-01-01

    In the last few years, many studies have investigated the role of imaging for improved diagnosis, assessment of treatment effects, and determining prognosis in patients with axial spondyloarthritis (SpA). Recent research has primarily focused on the utility of magnetic resonance imaging (MRI) for...... improved diagnosis of patients with non-radiographic axial SpA, and in particular on the classification utility of the MRI criteria as defined by the Assessment of Spondyloarthritis International Society (ASAS). New and more sensitive methods for evaluation of MRI of the sacroiliac joints have been...... developed and have provided insight into effects of treatment on structural progression and the interrelationships between different lesions visualized by MRI. This review gives an overview of the recent advances in imaging of the axial skeleton in axial SpA from a clinical perspective....

  3. Skeletonization of Deformed CAPTCHAs Using Pixel Depth Approach

    Directory of Open Access Journals (Sweden)

    Jingsong Cui

    2011-12-01

    Full Text Available CAPTCHA is a standard security technology that presents test to tell computers and humans apart. Nowadays the most widely deployed CAPTCHAs are text-based schemes, which rely on sophisticated distortion of text images aimed at rendering them unrecognizable to the state of the art of pattern recognition methods. Generally, the skeletonization of character is acknowledged as one of the most significant parts in character recognition. The skeleton which keeps the topology information as well as reduces the computational complexity is an excellent and robust structural feature to noise and deformation. In this paper, a depth-based approach is proposed in order to locate the skeleton point. In order to strike the balance between efficiency and robustness against distortion, three fault tolerance techniques have been applied in the extraction process. Then in the amendment stage, we use noise patterns to filter redundant points. Experiments are conducted and positive results are achieved, which show that the depth-based skeletonization scheme is applicable to the widely used CAPTCHA images, and the skeleton is robust against rotated, distorted or conglutinated characters.

  4. The conservation treatment of Canterbury Museum's blue whale skeleton

    International Nuclear Information System (INIS)

    The 26.5-metre-long blue whale skeleton, retrieved in 1908 from the West Coast of New Zealand's South Island, has been exhibited at the Canterbury Museum for 80 years outdoors, under shelter. Environmental conditions have contributed to the gradual deterioration of the skeleton, its mount structure and previous repair materials. The skeleton's significance as one of the largest articulated animals in the world, and its unique history of local importance, has prompted the development of a major conservation treatment and rearticulation project. Following examination, research and testing, the skeleton was de-installed to stabilise it in preparation for a new exhibition. Analysis of skeletal material was undertaken prior to beginning treatment. Conservation treatment included superficial cleaning, consolidation of embrittled portions of bone, removal of the previous invasive mount and repair materials, pinning and adhesion of detached bone sections, and filling and inpainting the wide variety of voids resulting from the original mount design and repairs. The organic polymer selected for consolidation, adhesion, filling (mixed with glass micro-balloons) and in inpainting (mixed with dry pigments) was Paraloid B72 dissolved in acetone. Detached bone portions were pinned with carbon fibre tube. The skeleton is anticipated to be rearticulated for installation in a new atrium. (author). 14 refs., 35 figs

  5. Determination of digestible isoleucine: lysine ratio in diets for laying hens aged 42-58 weeks

    Directory of Open Access Journals (Sweden)

    Heloisa Helena de Carvalho Mello

    2012-05-01

    Full Text Available Two hundred and fifty-two Hy-Line W36 laying hens were allotted in a completely randomized design with 6 treatments, 7 replicates and 6 hens per experimental unit in order to determine the ideal ratio of isoleucine (Ile in relation to lysine (Lys to laying hens aged 42-58 weeks. Experimental diets contained digestible Ile at different levels, resulting in different Ile:Lys ratios (0.73:1; 0.78:1; 0.83:1; 0.88:1; 0.93:1 and 0.98:1. A basal diet was formulated to provide Isoleucine in levels below recommendations. This diet was supplemented with L-isoleucine to make up the 6 diets. Each diet was made isonitrogenous by varying the dietary contents of glutamic acid and isocaloric by adjusting the contents of cornstarch. All essential amino acids were provided proportionally to lysine. Egg production, egg weight, egg mass, feed conversion ratio, albumen, yolk and eggshell contents were recorded and compiled at every 28-day period. No differences were observed in the performance over a wide range of dietary isoleucine concentrations from 5.76 to 7.73 g/kg corresponding to 0.73:1 to 0.98:1 Ile:Lys ratios. The lowest Ile:Lys ratio (0.73:1 was sufficient to ensure satisfactory performance of birds, corresponding to the consumption of 534 mg of isoleucine and 731 mg of lysine/day.

  6. Removing a Major Uncertainty in Mass and Age Determinations of Young Stars

    Science.gov (United States)

    Huerta, Marcos; Hartigan, Patrick

    2005-08-01

    Mass and age measurements of young stars rely on the stars' placement in an HR diagram relative to pre-main-sequence evolutionary tracks. Uncertainties in T_eff include a systematic error introduced by converting spectral types to T_eff according to a conversion scale derived from main-sequence stars. The advent of sophisticated synthetic spectra and modern molecular opacities offers us an opportunity to determine a new T_eff scale designed for young stars. We propose to measure T_eff for a large sample of non- accreting (weak-lined) T Tauri stars using low resolution red spectra on Goldcam. The resulting spectra will make it possible to estimate T_eff for any young star by simply finding the best spectral match with a star in our sample. This procedure will also work for accreting (classical) T Tauri stars, where weak-lined T Tauri stars are used as photospheric templates to distinguish stellar features from accretion signatures.

  7. The age of the halo as determined from halo field stars

    Science.gov (United States)

    Guo, Jin-Cheng; Liu, Chao; Liu, Ji-Feng

    2016-03-01

    The age of the Galactic halo is a critical parameter that can constrain the origin of the stellar halo. In general, the Galactic stellar halo is believed to be very old. However, different independent measurements and techniques based on various types of stars are required so that the age estimates of the Galactic halo are accurate, robust, and reliable. In this work, we provide a novel approach to determine the age of the halo with turn-off stars. We first carefully select 63 field halo turn-off stars from the literature. Then, we compare them with the GARSTEC model, which takes the process of atomic diffusion into account in the B - V vs. metallicity plane. Finally, we run Monte Carlo simulations to consider the uncertainty of the color index and obtain the age of 10.5 ± 1.5 Gyr. This result is in agreement with previous studies. Future works are needed to collect more turn-off samples with more accurate photometry to reduce the uncertainty of the age.

  8. Social relations and filial maturity in middle-aged adults: contextual conditions and psychological determinants.

    Science.gov (United States)

    Perrig-Chiello, P; Sturzenegger, M

    2001-02-01

    The aim of this paper is to highlight the contextual and psychological preconditions of parent help and helpfulness in a sample of 260 middle-aged persons belonging to two age groups, 40-45 years and 50-55 years. In a first step we want to focus on the description of the contextual situation of the persons of this "hinge generation": What are their available social networks; what are their commitments towards children and parents in terms of perceived obligation and investment; how is their perceived balance of giving and receiving; how do they anticipate and experience dependency of their parents? In a second step we will highlight the readiness of middle-aged women and men to help their parents as well as the effectively reported help. Here we are interested in the psychological determinants of such attitude and behaviour. Structural equation models are performed to estimate the predictory power of personality variables, control beliefs and reported stress (family and job) on filial helpfulness and help. Results suggest that differential aspects such as gender and age group explain a large amount of variance of the variables intergenerational commitment and satisfaction with social networks and have--along with personality variables--a strong impact on filial help and helpfulness of middle-aged adults. PMID:11310223

  9. The reliability of the Greulich-Pyle method in bone age determination among Australian children

    International Nuclear Information System (INIS)

    Bone age (BA) determination in skeletally immature children has been used as a measurement of growth for many years. The Greulich-Pyle (G&P) method of estimating BA is most commonly used. The standards used within this atlas were compiled from research conducted on normal white children in the United States, during the 1930s. The applicability of G&P beyond populations similar to its own can be variable. The aim of this study was to determine the accuracy of G&P in BA determination among Australian children. Hand X-rays of children under the age of 18, investigated for trauma, were recruited. Mean differences between BA, according to the standards of G&P, and chronological age (CA) were compared among all patients and subgroups according to age, gender and left versus right hand. Between January and December 2010, 654 children underwent hand X-rays, 406 of these were included (276 males and 130 females). Overall BA was 2.2 months less than CA (P-value=0.005). BA of males and females was estimated to be 1.5 months (P-value=0.142) and 3.7 months (P-value=0.002) less than their CA respectively. No statistically significant difference was identified with intra-observer (P-value=0.846) and inter-observer interpretations (P-value=0.102). Our results show that the standards of G&P are an accurate means of BA determination in Australian children.

  10. Determination of the functional status of vestibular apparatus at children aged 5-6 years old.

    Directory of Open Access Journals (Sweden)

    Moiseenko E.K.

    2012-02-01

    Full Text Available The physiological methods of determination of the functional state of vestibular analyzer are considered. The indexes of systole and diastole pressure, frequencies of heart-throbs, are chosen. Methods were used before and after standard vestibular irritation. Research was conducted on the base of child's preschool establishment. In it took part 120 children in age 5 - 6 years. Insufficient development of vestibular analyzer is set for children. Selected exercise for the improvement of spatial orientation and statodynamic stability.

  11. A secondary analysis to determine variations of dental arch measurements with age and gender among Ugandans

    OpenAIRE

    Okori, Hilda; Apolot, Pricilla S.; Mwaka, Erisa; Tumusiime, Gerald; Buwembo, William; Munabi, Ian G.

    2015-01-01

    Background Dental arch dimensions are useful in dental practice and in forensic odontology. Local data is essential because ethnic differences exist in dental arch dimensions. In the Ugandan population no studies had been done on dental arch dimensions. The objective of the current study was to determine the variations in dental arch dimensions with age and gender in a sample of dental casts from the Ugandan population. Method This was a secondary analysis of dental casts previously prepared ...

  12. Application of the fission track method to determination of temperature aging and of uranium concentrations

    International Nuclear Information System (INIS)

    In part I fission track counting has been applied to a) age determination of apatite and titanite from Sweden and an estimation of their initial temperatures b) determination of uranium content of waters from droplets evaporated on plastic foils. In part II absorption spectrometry was used to investigate the recovery from radiation defects in natural apatite. Conclusions are drawn on the radiations defect healing mechanism during annealing. Part of the content of this work has already been published in journals and conference papers. (G.Q.)

  13. Age and Heat Stress as Determinants of Telomere Length in a Long-Lived Fish, the Siberian Sturgeon.

    Science.gov (United States)

    Simide, Rémy; Angelier, Frédéric; Gaillard, Sandrine; Stier, Antoine

    2016-01-01

    Telomeres shorten at each cell division due to the end-replication problem but also in response to oxidative stress. Consequently, telomeres shorten with age in many endotherms, and this shortening is accelerated under stressful environmental conditions. Data in ectotherm vertebrates remain scarce so far, so our goal was to review existing data for fish and to test the influence of age and stress on telomere length in a very long-lived fish, the Siberian sturgeon (Acipenser baerii). Our review of the literature revealed age-related telomere shortening in approximately half of the published studies. In the Siberian sturgeon, we found a significant telomere shortening with age, both at the intraindividual level using red blood cells (-12.5% in 16 mo) and at the interindividual level using cross-sectional samples of fin over an age range of 8 yr. We also found that heat stress (30°C) significantly reduced telomere length by 15.0% after only 1 mo of exposure. Our results highlight that both age and stressful environmental conditions might be important determinants of telomere length in fish. PMID:27617363

  14. The Age of the Directly Imaged Planet Host Star κ Andromedae Determined from Interferometric Observations

    Science.gov (United States)

    Jones, Jeremy; White, R. J.; Quinn, S.; Ireland, M.; Boyajian, T.; Schaefer, G.; Baines, E. K.

    2016-05-01

    κ Andromedae, an early-type star that hosts a directly imaged low-mass companion, is expected to be oblate due to its rapid rotational velocity (v sin i = ˜162 km s-1). We observed the star with the CHARA Array’s optical beam combiner, PAVO, measuring its size at multiple orientations and determining its oblateness. The interferometric measurements, combined with photometry and this v sin i value are used to constrain an oblate star model that yields the fundamental properties of the star and finds a rotation speed that is ˜85% of the critical rate and a low inclination of ˜30°. Three modeled properties (the average radius, bolometric luminosity, and equatorial velocity) are compared to MESA evolution models to determine an age and mass for the star. In doing so, we determine an age for the system of {47}-40+27 Myr. Based on this age and previous measurements of the companion’s temperature, the BHAC15 evolution models imply a mass for the companion of {22}-9+8 M J.

  15. The Age of the Directly-Imaged Planet Host Star $\\kappa$ Andromedae Determined From Interferometric Observations

    CERN Document Server

    Jones, Jeremy; Quinn, S; Ireland, M; Boyajian, T; Schaefer, G; Baines, E K

    2016-01-01

    $\\kappa$ Andromedae, an early type star that hosts a directly imaged low mass companion, is expected to be oblate due to its rapid rotational velocity ($v\\sin i$ = $\\sim$162 $\\mathrm{km~s^{-1}}$). We observed the star with the CHARA Array's optical beam combiner, PAVO, measuring its size at multiple orientations and determining its oblateness. The interferometric measurements, combined with photometry and this $v\\sin i$ value are used to constrain an oblate star model that yields the fundamental properties of the star and finds a rotation speed that is $\\sim$85\\% of the critical rate and a low inclination of $\\sim$30$^\\circ$. Three modeled properties (the average radius, bolometric luminosity, and equatorial velocity) are compared to MESA evolution models to determine an age and mass for the star. In doing so, we determine an age for the system of 47$^{+27}_{-40}$ Myr. Based on this age and previous measurements of the companion's temperature, the BHAC15 evolution models imply a mass for the companion of 22$^...

  16. A partial skeleton of a new lamniform mackerel shark from the Miocene of Europe

    Directory of Open Access Journals (Sweden)

    Jürgen Kriwet

    2015-12-01

    Full Text Available Cenozoic lamniform sharks are mostly represented by isolated teeth and vertebrae, whereas articulated skeletal remains are usually very scarce. Here, we describe a partial skeleton of an extinct lamniform shark consisting of 42 slightly disarticulated teeth, 49 vertebrae, and additional unidentifiable cranial and postcranial remains. The specimen originates from the Miocene mica-clay of Groß Pampau (North Germany, which is of late Langenfeldian age (= Serravallian-Tortonian boundary; middle–late Miocene. A total of 13 measurements of each tooth, as well as morphological features, were used to reconstruct the dentition of this specimen and to provide detailed taxonomic information. Additionally, the total body size and age at death were established using methodologies based on vertebral and tooth measurements and vertebral centra growth ring counts, respectively. The specimen undoubtedly represents the most complete individual of “Carcharodon (= Isurus escheri”, previously known only from a few isolated teeth. The dental pattern (e.g., marked dignathic and monognathic heterodonty patterns; only slightly labio-lingually compressed upper teeth; upper teeth slender with distally inclined or curved main cusps; massive, hook-like upper intermediate tooth; main cusps with crenulated cutting edges; lateral cusplets in teeth of all ontogenetic stages clearly separates this shark from all hitherto known Cenozoic and Recent lamnids and a new genus, Carcharomodus, consequently is introduced. Carcharomodus escheri comb. nov. is a characteristic element of late early Miocene to the Pliocene Western and Central European fish faunas. All previously identified Pacific occurrences represent a different taxon. We estimate that the specimen had a total body length of about 4 m and that it was older than 10 years and thus might have reached maturity before death, as indicated by all available evidence.

  17. Canaliculi in the tessellated skeleton of cartilaginous fishes

    Energy Technology Data Exchange (ETDEWEB)

    Dean, M.N.; Socha, J.J.; Hall, B.K.; Summers, A.P. (UCI); (Dalhousie U.); (VPI-SU)

    2010-08-04

    The endoskeletal elements of sharks and rays are comprised of an uncalcified, hyaline cartilage-like core overlain by a thin fibro-ceramic layer of mineralized hexagonal tiles (tesserae) adjoined by intertesseral fibers. The basic spatial relationships of the constituent tissues (unmineralized cartilage, mineralized cartilage, fibrous tissue) are well-known - endoskeletal tessellation is a long-recognized synapomorphy of elasmobranch fishes - but a high-resolution and three-dimensional (3D) understanding of their interactions has been hampered by difficulties in sample preparation and lack of technologies adequate for visualizing microstructure and microassociations. We used cryo-electron microscopy and synchrotron radiation tomography to investigate tessellated skeleton ultrastructure but without damage to the delicate relationships between constituent tissues or to the tesserae themselves. The combination of these techniques allowed visualization of never before appreciated internal structures, namely passages connecting the lacunar spaces within tesserae. These intratesseral 'canaliculi' link consecutive lacunar spaces into long lacunar strings, radiating outward from the center of tesserae. The continuity of extracellular matrix throughout the canalicular network may explain how chondrocytes in tesserae remain vital despite encasement in mineral. Extracellular fluid exchange may also permit transmission of nutrients, and mechanical and mineralization signals among chondrocytes, in a manner similar to the canalicular network in bone. These co-adapted mechanisms for the facilitated exchange of extracellular material suggest a level of parallelism in early chondrocyte and osteocyte evolution.

  18. Determination of the micro-nutrient elements and the toxic in food of peruvian children of the city of Lima. Part I: determination through instrumental neutron activation of Ca, Cl, K, Mg and Na in samples of milk and milk with cereal consumed by peruvian children in the age of weaning

    International Nuclear Information System (INIS)

    The contents of Ca, Cl, K, Mg and Na in milk and milk with cereal, consumed by the peruvian children were determined by short irradiation INAA using RP-10 reactor, with a thermal flux of 1013 n/cm-2s-1 and a pneumatic system. The comparative method with solutions of primary standards of each element determined was used. The IAEA-A11-milk powder, IAEA-H4-animal muscle and IAEA-V10-hay powder, reference materials were periodically analyzed, together with the samples, in order to check the quality of analytical results. (authors) 3 refs., 3 tabs, 2 figs

  19. A vanished history of skeletonization in Cambrian comb jellies.

    Science.gov (United States)

    Ou, Qiang; Xiao, Shuhai; Han, Jian; Sun, Ge; Zhang, Fang; Zhang, Zhifei; Shu, Degan

    2015-07-01

    Ctenophores are traditionally regarded as "lower" metazoans, sharing with cnidarians a diploblastic grade of organization. Unlike cnidarians, where skeletonization (biomineralization and sclerotization) evolved repeatedly among ecologically important taxa (for example, scleractinians and octocorals), living ctenophores are characteristically soft-bodied animals. We report six sclerotized and armored ctenophores from the early Cambrian period. They have diagnostic ctenophore features (for example, an octamerous symmetry, oral-aboral axis, aboral sense organ, and octaradially arranged ctene rows). Unlike most modern counterparts, however, they lack tentacles, have a sclerotized framework, and have eight pairs of ctene rows. They are resolved as a monophyletic group (Scleroctenophora new class) within the ctenophores. This clade reveals a cryptic history and sheds new light on the early evolution of this basal animal phylum. Skeletonization also occurs in some other Cambrian animal groups whose extant members are exclusively soft-bodied, suggesting the ecological importance of skeletonization in the Cambrian explosion. PMID:26601209

  20. Hollow silica-copper-carbon anodes using copper metal-organic frameworks as skeletons

    Science.gov (United States)

    Sun, Zixu; Xin, Fengxia; Cao, Can; Zhao, Chongchong; Shen, Cai; Han, Wei-Qiang

    2015-12-01

    Hollow silica-copper-carbon (H-SCC) nanocomposites are first synthesized using copper metal-organic frameworks as skeletons to form Cu-MOF@SiO2 and then subjected to heat treatment. In the composites, the hollow structure and the void space from the collapse of the MOF skeleton can accommodate the huge volume change, buffer the mechanical stress caused by lithium ion insertion/extraction and maintain the structural integrity of the electrode and a long cycling stability. The ultrafine copper with a uniform size of around 5 nm and carbon with homogeneous distribution from the decomposition of the MOF skeleton can not only enhance the electrical conductivity of the composite and preserve the structural and interfacial stabilization, but also suppress the aggregation of silica nanoparticles and cushion the volume change. In consequence, the resulting material as an anode for lithium-ion batteries (LIBs) delivers a reversible capacity of 495 mA h g-1 after 400 cycles at a current density of 500 mA g-1. The synthetic method presented in this paper provides a facile and low-cost strategy for the large-scale production of hollow silica/copper/carbon nanocomposites as an anode in LIBs.Hollow silica-copper-carbon (H-SCC) nanocomposites are first synthesized using copper metal-organic frameworks as skeletons to form Cu-MOF@SiO2 and then subjected to heat treatment. In the composites, the hollow structure and the void space from the collapse of the MOF skeleton can accommodate the huge volume change, buffer the mechanical stress caused by lithium ion insertion/extraction and maintain the structural integrity of the electrode and a long cycling stability. The ultrafine copper with a uniform size of around 5 nm and carbon with homogeneous distribution from the decomposition of the MOF skeleton can not only enhance the electrical conductivity of the composite and preserve the structural and interfacial stabilization, but also suppress the aggregation of silica nanoparticles and

  1. Effect of spaceflight on the non-weight-bearing bones of rat skeleton

    Science.gov (United States)

    Simmons, D. J.; Russell, J. E.; Winter, F.; Tran Van, P.; Vignery, A.; Baron, R.; Rosenberg, G. D.; Walker, W. V.

    1983-01-01

    The effects of weightlessness on the integrated growth and remodeling of nonweight-bearing bones (the mandibles, teeth, and ribs) were studied. Rats prelabeled with tetracycline to mark the surfaces of bone and tooth formation were subjected to spaceflight conditions for 18.5 days, followed by further injections of tetracycline on days 6 and 29 postflight.Results show that spaceflight conditions did not alter the rate of periosteal bone formation in the ribs and regions of the mandibles covered by masticatory muscles, although bone formation-calcification rates were found to be impaired at those sites in the jaw that had no contiguous muscle (molar region). The remodeling activity on the alveolar bone around the buccal roots of the molar teeth was found to be significantly reduced. While total Ca, P, and hydroxyproline concentrations in the jaws, incisors, and ribs were normal after spaceflight, it was determined that weightless conditions caused a delay in the maturation of bone mineral and matrix in the jaws. These anomalies were found to be corrected by 29 days postflight. These results indicate that most of the nonweight-bearing bones of the rat skeleton are at risk to the effects of weightlessness.

  2. Aging Behavior of Al 6061 Alloy Processed by High-Pressure Torsion and Subsequent Aging

    Science.gov (United States)

    Mohamed, Intan Fadhlina; Lee, Seungwon; Edalati, Kaveh; Horita, Zenji; Hirosawa, Shoichi; Matsuda, Kenji; Terada, Daisuke

    2015-06-01

    A process to achieve strengthening in an Al 6061 alloy by grain refinement to ~200 nm using high-pressure torsion (HPT) and fine precipitation using aging treatment is studied. It is shown that although aging of the HPT-processed sample is effective for extra strengthening of the alloy, the imposed shear strain and the aging temperature should be selected carefully. The HPT processing after 5 turns leads high saturation hardness and tensile strength of 163 Hv and 470 MPa, respectively. The hardness at the saturation level remains the same during aging at 373 K (100 °C), while the hardness decreases by aging at 423 K (150 °C). When the disks are processed for 0.75 turns (lower shear strains) and aged at 373 K (100 °C), the hardness increases above the hardness level at the saturation because of the formation of B' and β' precipitates. Quantitative analyses indicate that three major hardening mechanisms contribute to the total hardening: grain boundary hardening through the Hall-Petch relationship, dislocation hardening through the Bailey-Hirsch relationship and precipitation hardening through the Orowan relationship. This study shows that the contribution of different strengthening mechanisms can be estimated using a linear additive relationship in ultrafine-grained aluminum alloys.

  3. Free radicals created by radiation and aging symptoms

    International Nuclear Information System (INIS)

    The universality of aging implies that its cause is basically the same in all species. A free radical hypothesis of aging has been proposed that the free radicals produced during normal metabolism of the cell over time damage DNA and other macromolecules leading to degenerative diseases, malignancies, and eventual death of vital cells which in turn causes aging and death of the organism. This hypothesis is supported by several observations. Radiation produces its biologic effect through free radical formation and causes premature aging. Second, the age pigment lipo fuscin is associated with lipid peroxidation. The hypothesis that oxygen radicals play a role in aging is also supported by the observation that, in general, long-lived species produce less endogenous free oxygen radicals because of their lower metabolic rate. Long-lived animals also have more superoxide dismutase than do their short-lived counterparts, and animal species with the longest lifespan have the highest levels of superoxide dismutase. Oxidative DNA damage is rapidly and effectively repaired. It has been estimated that there are several thousand oxidative DNA damage sites in a human cell every day, and the majority of these are repaired. However, a small fraction of unrepaired lesions could cause permanent changes in DNA and might be a major contributor to aging and cancer. A consequence of the free radical hypothesis of aging is the idea that free radical scavenging agents might be used to prevent aging. (author)

  4. Determination of equivalent breast phantoms for different age groups of Taiwanese women: An experimental approach

    International Nuclear Information System (INIS)

    Purpose: Polymethylmethacrylate (PMMA) slab is one of the mostly used phantoms for studying breast dosimetry in mammography. The purpose of this study was to evaluate the equivalence between exposure factors acquired from PMMA slabs and patient cases of different age groups of Taiwanese women in mammography. Methods: This study included 3910 craniocaudal screen/film mammograms on Taiwanese women acquired on one mammographic unit. The tube loading, compressed breast thickness (CBT), compression force, tube voltage, and target/filter combination for each mammogram were collected for all patients. The glandularity and the equivalent thickness of PMMA were determined for each breast using the exposure factors of the breast in combination with experimental measurements from breast-tissue-equivalent attenuation slabs. Equivalent thicknesses of PMMA to the breasts of Taiwanese women were then estimated. Results: The average ± standard deviation CBT and breast glandularity in this study were 4.2 ± 1.0 cm and 54% ± 23%, respectively. The average equivalent PMMA thickness was 4.0 ± 0.7 cm. PMMA slabs producing equivalent exposure factors as in the breasts of Taiwanese women were determined for the age groups 30-49 yr and 50-69 yr. For the 4-cm PMMA slab, the CBT and glandularity values of the equivalent breast were 4.1 cm and 65%, respectively, for the age group 30-49 yr and 4.4 cm and 44%, respectively, for the age group 50-69 yr. Conclusions: The average thickness of PMMA slabs producing the same exposure factors as observed in a large group of Taiwanese women is less than that reported for American women. The results from this study can provide useful information for determining a suitable thickness of PMMA for mammographic dose survey in Taiwan. The equivalence of PMMA slabs and the breasts of Taiwanese women is provided to allow average glandular dose assessment in clinical practice.

  5. Determination of equivalent breast phantoms for different age groups of Taiwanese women: An experimental approach

    Energy Technology Data Exchange (ETDEWEB)

    Dong, Shang-Lung; Chu, Tieh-Chi; Lin, Yung-Chien; Lan, Gong-Yau; Yeh, Yu-Hsiu; Chen, Sharon; Chuang, Keh-Shih [Department of Biomedical Engineering and Environmental Sciences, National Tsing Hua University, 101 Section 2, Kuang-Fu Road, Hsinchu 30013, Taiwan (China); Department of Radiology, Cheng Hsin General Hospital, 45 Cheng Hsin Street, Pai-Tou District, Taipei 11220, Taiwan (China); Department of Medical Imaging and Radiological Sciences, Kaohsiung Medical University, 100 Shih-Chuan 1st Road, Kaohsiung 80708, Taiwan (China); Department of Biomedical Engineering and Environmental Sciences, National Tsing Hua University, 101 Section 2, Kuang-Fu Road, Hsinchu 30013, Taiwan (China)

    2011-07-15

    Purpose: Polymethylmethacrylate (PMMA) slab is one of the mostly used phantoms for studying breast dosimetry in mammography. The purpose of this study was to evaluate the equivalence between exposure factors acquired from PMMA slabs and patient cases of different age groups of Taiwanese women in mammography. Methods: This study included 3910 craniocaudal screen/film mammograms on Taiwanese women acquired on one mammographic unit. The tube loading, compressed breast thickness (CBT), compression force, tube voltage, and target/filter combination for each mammogram were collected for all patients. The glandularity and the equivalent thickness of PMMA were determined for each breast using the exposure factors of the breast in combination with experimental measurements from breast-tissue-equivalent attenuation slabs. Equivalent thicknesses of PMMA to the breasts of Taiwanese women were then estimated. Results: The average {+-} standard deviation CBT and breast glandularity in this study were 4.2 {+-} 1.0 cm and 54% {+-} 23%, respectively. The average equivalent PMMA thickness was 4.0 {+-} 0.7 cm. PMMA slabs producing equivalent exposure factors as in the breasts of Taiwanese women were determined for the age groups 30-49 yr and 50-69 yr. For the 4-cm PMMA slab, the CBT and glandularity values of the equivalent breast were 4.1 cm and 65%, respectively, for the age group 30-49 yr and 4.4 cm and 44%, respectively, for the age group 50-69 yr. Conclusions: The average thickness of PMMA slabs producing the same exposure factors as observed in a large group of Taiwanese women is less than that reported for American women. The results from this study can provide useful information for determining a suitable thickness of PMMA for mammographic dose survey in Taiwan. The equivalence of PMMA slabs and the breasts of Taiwanese women is provided to allow average glandular dose assessment in clinical practice.

  6. A Novel Bihomoflavanonol with an Unprecedented Skeleton from Pteridium aquilinum

    Institute of Scientific and Technical Information of China (English)

    CHEN Nai-dong; CHEN Nai-fu; CHEN Cun-wu; ZHANG Li

    2013-01-01

    Objective To seek the flavonoids with the unique structure and to investigate the chemical ingredients in the flavonoid-rich plant-Pteridium aquilinum.Methods The 80% EthOH extract from the degreased powder of P.aquilinum was partitioned by petroleum ether,CHCl3,EtOAc,n-butanol,and water,respectively.The EtOAc fraction was sequentially subjected to silica gel column,repeated Sephadex LH-20 column,and preparative TLC to give a new compound.The antitumor activity of the novel flavonoid was primarily evaluated by MTT.Results Compound 1,a biflavonoid with the unique structure named as pteridium Ⅲ with an unprecedented bihomoflavanonol skeleton,was isolated from P.aquilinum.Compound 1 showed the in vitro antitumor activity against lung cancer cell NCI-H46,melanoma cell A375,and glioma cell U-7MG corresponding to the IC50 values of 22.9,106.7,and 1540.5 μmol/L,respectively.No inhibition on gastric carcinoma SGC-7901 and prostatic carcinoma PC-3 was observed in the experiment.Conclusion A rare bihomoflavononol derivative,pteridium Ⅲ,is obtained from the plant,which could enrich our knowedge on the chemical structures of flavonoids and bioactive constituents in P.aquilinum.

  7. Ocean acidification causes structural deformities in juvenile coral skeletons.

    Science.gov (United States)

    Foster, Taryn; Falter, James L; McCulloch, Malcolm T; Clode, Peta L

    2016-02-01

    Rising atmospheric CO2 is causing the oceans to both warm and acidify, which could reduce the calcification rates of corals globally. Successful coral recruitment and high rates of juvenile calcification are critical to the replenishment and ultimate viability of coral reef ecosystems. Although elevated Pco2 (partial pressure of CO2) has been shown to reduce the skeletal weight of coral recruits, the structural changes caused by acidification during initial skeletal deposition are unknown. We show, using high-resolution three-dimensional x-ray microscopy, that ocean acidification (Pco2 ~900 μatm, pH ~7.7) not only causes reduced overall mineral deposition but also a deformed and porous skeletal structure in newly settled coral recruits. In contrast, elevated temperature (+3°C) had little effect on skeletal formation except to partially mitigate the effects of elevated Pco2. The striking structural deformities we observed show that new recruits are at significant risk, being unable to effectively build their skeletons in the Pco2 conditions predicted to occur for open ocean surface waters under a "business-as-usual" emissions scenario [RCP (representative concentration pathway) 8.5] by the year 2100. PMID:26989776

  8. [Investigation of vasoactive agents with indole skeletons at Richter Ltd].

    Science.gov (United States)

    Kárpáti, Egon; Bíró, Katalin; Kukorelli, Tibor

    2002-01-01

    Investigation of agents with indol skeleton was started in Richter Ltd. 50 years ago. This paper presents the results obtained by Richter's scientists. At first, a vasoactive alcaloid, vincamine was extracted from the leaves of Vinca minor in industrial quantity in 1955. This agent selectively improves the cerebral blood supply. Vincamine (Devincan) is used for the treatment of cerebrovascular disorders from 1959. Vinpocetine (Cavinton), the most powerful vasoactive compound was produced by transforming the chemical structure of vincamine. Cavinton is a cis(3S,16S)-derivate of vincamine having antianoxic, antiischaemic and neuroprotective properties. Therefore, it is frequently used in the therapy of cerebral disorders of vascular origin. Cavinton was introduced into clinical practice in 1978. At present, Cavinton tablets are approved in 47 countries. The third compound, vintoperol is a trans(3S,16R)-derivate of vincamine. Vintoperol proved to be a powerful enhancer of blood flow in the lower extremities. Because of its toxic side effects the agent is not used in clinical practice. PMID:12426785

  9. Skeleton Graph Matching vs. Maximum Weight Cliques aorta registration techniques.

    Science.gov (United States)

    Czajkowska, Joanna; Feinen, C; Grzegorzek, M; Raspe, M; Wickenhöfer, R

    2015-12-01

    Vascular diseases are one of the most challenging health problems in developed countries. Past as well as ongoing research activities often focus on efficient, robust and fast aorta segmentation, and registration techniques. According to this needs our study targets an abdominal aorta registration method. The investigated algorithms make it possible to efficiently segment and register abdominal aorta in pre- and post-operative Computed Tomography (CT) data. In more detail, a registration technique using the Path Similarity Skeleton Graph Matching (PSSGM), as well as Maximum Weight Cliques (MWCs) are employed to realise the matching based on Computed Tomography data. The presented approaches make it possible to match characteristic voxels belonging to the aorta from different Computed Tomography (CT) series. It is particularly useful in the assessment of the abdominal aortic aneurysm treatment by visualising the correspondence between the pre- and post-operative CT data. The registration results have been tested on the database of 18 contrast-enhanced CT series, where the cross-registration analysis has been performed producing 153 matching examples. All the registration results achieved with our system have been verified by an expert. The carried out analysis has highlighted the advantage of the MWCs technique over the PSSGM method. The verification phase proves the efficiency of the MWCs approach and encourages to further develop this methods. PMID:26099640

  10. Dressed skeleton expansion and the coupling scale ambiguity problem

    International Nuclear Information System (INIS)

    Perturbative expansions in quantum field theories are usually expressed in powers of a coupling constant. In principle, the infinite sum of the expansion series is independent of the renormalization scale of the coupling constant. In practice, there is a remnant dependence of the truncated series on the renormalization scale. This scale ambiguity can severely restrict the predictive power of theoretical calculations. The dressed skeleton expansion is developed as a calculational method which avoids the coupling scale ambiguity problem. In this method, physical quantities are expressed as functional expansions in terms of a coupling vertex function. The arguments of the vertex function are given by the physical momenta of each process. These physical momenta effectively replace the unspecified renormalization scale and eliminate the ambiguity problem. This method is applied to various field theoretical models and its main features and limitations are explored. For quantum chromodynamics, an expression for the running coupling constant of the three-gluon vertex is obtained. The effective coupling scale of this vertex is shown to be essentially given by μ2 ∼ Qmin2Qmed2/Qmax2 where Qmin2Qmed2/Qmax2 are respectively the smallest, the next-to-smallest and the largest scale among the three gluon virtualities. This functional form suggests that the three-gluon vertex becomes non-perturbative at asymmetric momentum configurations. Implications for four-jet physics is discussed

  11. Osteoporosis therapy: a novel insight from natural homeostatic system in the skeleton.

    Science.gov (United States)

    Sugiyama, T; Kim, Y T; Oda, H

    2015-02-01

    The skeleton normally responds to mechanical environment to maintain the resulting elastic deformation (strain) of bone, while increased bone strength by an osteoporosis drug results in decreased bone strain. Thus, it can be hypothesized that the effect of osteoporosis therapy is limited by natural homeostatic system in the skeleton. This logic is consistent with the fact that there exists a powerful effect that returns bone mass to its pre-treatment level after the withdrawal of treatment with osteoporosis agents. The present hypothesis provides a new significant insight into the mechanisms by which osteoporosis drugs improve bone fragility. Here we briefly discuss the effects of teriparatide, romosozumab, and odanacatib on bones in animals and humans. PMID:25288445

  12. Scaphocephaly in a prehistoric skeleton from Harappa, Pakistan.

    Science.gov (United States)

    Kennedy, K A; Lovell, N C; Lukacs, J R; Hemphill, B E

    1993-03-01

    Irregularities of cranial suture closure resulting in scaphocephaly are documented for a number of prehistoric and historic human populations of the eastern and western hemispheres, but what may be the first recorded case from southern Asia appeared during the 1987 archaeological field season at the Indus Valley Civilization site of Harappa, Pakistan. The female specimen with this condition also exhibits indicators of developmental abnormalities in the postcranial skeleton. These features are discussed in the context of assessing anatomical and ontogenetical relationships of craniostenostic eccentricities with abnormalities of facial, dental and postcranial regions of the skeletons of scaphocephalic individuals. PMID:8476271

  13. Holotestoid: a computational model for testing hypotheses about echinoid skeleton form and growth.

    Science.gov (United States)

    Abou Chakra, Maria; Stone, Jonathon Richard

    2011-09-21

    Regular echinoid skeletons, or tests, comprise plate patterns and overall shapes that have proven challenging to analyse solely on the basis of any one approach or process. Herein, we present a computational model, Holotestoid, that emulates four macrostructural ontogenic processes involved in test growth (plate growth, plate addition, plate interaction, and plate gapping). We devise a geometric representation for analysing tests and describe how we use analogies (bubble interactions and close-packing) to emulate the processes. In the computational model, the emulated processes are used to determine the plate size and plate shape and combined to simulate a growth zone. We simulated growth zones for Arbacia punctulata and for Strongylocentrotus franciscanus by changing the value for one parameter, the ambulacral column angle. We quantitatively compared morphological features for simulated forms to those for real specimens to test the computational model. Additionally, we simulated growth zones for A. punctulata, S. franciscanus, Eucidaris thouarsii, and Mellita quinquiesperforata by changing three parameters, ambulacral column angle, peristome radius to apical system radius ratio, and apical system radius to column length ratio. Holotestoid can be used to explain morphological disparity among echinoid tests. PMID:21756918

  14. Wear determination in braking systems by radioisotopes

    International Nuclear Information System (INIS)

    Friction and wear behaviour of friction couples has been tested applying loads and sliding speeds. The determination was carried out by direct measurements of the lining material and by surface activation of the opposite material with protons. The application limits of several braking materials could be determined and compared

  15. Individual Differences in Exercise Behavior: Stability and Change in Genetic and Environmental Determinants From Age 7 to 18.

    Science.gov (United States)

    Huppertz, Charlotte; Bartels, Meike; de Zeeuw, Eveline L; van Beijsterveldt, Catharina E M; Hudziak, James J; Willemsen, Gonneke; Boomsma, Dorret I; de Geus, Eco J C

    2016-09-01

    Exercise behavior during leisure time is a major source of health-promoting physical activity and moderately tracks across childhood and adolescence. This study aims to investigate the absolute and relative contribution of genes and the environment to variance in exercise behavior from age 7 to 18, and to elucidate the stability and change of genetic and shared environmental factors that underlie this behavior. The Netherlands Twin Register collected data on exercise behavior in twins aged approximately 7, 10, 12, 14, 16 and 18 years (N = 27,332 twins; 48 % males; 47 % with longitudinal assessments). Three exercise categories (low, middle, high) were analyzed by means of liability threshold models. First, a univariate model was fitted using the largest available cross-sectional dataset with linear and quadratic effects of age as modifiers on the means and variance components. Second, a simplex model was fitted on the longitudinal dataset. Heritability was low in 7-year-olds (14 % in males and 12 % in females), but gradually increased up to age 18 (79 % in males and 49 % in females), whereas the initially substantial relative influence of the shared environment decreased with age (from 80 to 4 % in males and from 80 to 19 % in females). This decrease was due to a large increase in the genetic variance. The longitudinal model showed the genetic effects in males to be largely stable and to accumulate from childhood to late adolescence, whereas in females, they were marked by both transmission and innovation at all ages. The shared environmental effects tended to be less stable in both males and females. In sum, the clear age-moderation of exercise behavior implies that family-based interventions might be useful to increase this behavior in children, whereas individual-based interventions might be better suited for adolescents. We showed that some determinants of individual differences in exercise behavior are stable across childhood and youth, whereas

  16. Interaction between PNPLA3 I148M variant and age at infection in determining fibrosis progression in chronic hepatitis C.

    Directory of Open Access Journals (Sweden)

    Stella De Nicola

    Full Text Available BACKGROUND AND AIMS: The PNPLA3 I148M sequence variant favors hepatic lipid accumulation and confers susceptibility to hepatic fibrosis and hepatocellular carcinoma. The aim of this study was to estimate the effect size of homozygosity for the PNPLA3 I148M variant (148M/M on the fibrosis progression rate (FPR and the interaction with age at infection in chronic hepatitis C (CHC. METHODS: FPR was estimated in a prospective cohort of 247 CHC patients without alcohol intake and diabetes, with careful estimation of age at infection and determination of fibrosis stage by Ishak score. RESULTS: Older age at infection was the strongest determinant of FPR (p<0.0001. PNPLA3 148M/M was associated with faster FPR in individuals infected at older age (above the median, 21 years; -0.64±0.2, n = 8 vs. -0.95±0.3, n = 166 log10 FPR respectively; p = 0.001; confirmed for lower age thresholds, p<0.05, but not in those infected at younger age (p = ns. The negative impact of PNPLA3 148M/M on fibrosis progression was more marked in subjects at risk of altered hepatic lipid metabolism (those with grade 2-3 steatosis, genotype 3, and overweight; p<0.05. At multivariate analysis, PNPLA3 148M/M was associated with FPR (incremental effect 0.08±0.03 log10 fibrosis unit per year; p = 0.022, independently of several confounders, and there was a significant interaction between 148M/M and older age at infection (p = 0.025. The association between 148M/M and FPR remained significant even after adjustment for steatosis severity (p = 0.032. CONCLUSIONS: We observed an interaction between homozygosity for the PNPLA3 I148M variant and age at infection in determining fibrosis progression in CHC patients.

  17. Cloning Nacre's 3D Interlocking Skeleton in Engineering Composites to Achieve Exceptional Mechanical Properties.

    Science.gov (United States)

    Zhao, Hewei; Yue, Yonghai; Guo, Lin; Wu, Juntao; Zhang, Youwei; Li, Xiaodong; Mao, Shengcheng; Han, Xiaodong

    2016-07-01

    Ceramic/polymer composite equipped with 3D interlocking skeleton (3D IL) is developed through a simple freeze-casting method, exhibiting exceptionally light weight, high strength, toughness, and shock resistance. Long-range crack energy dissipation enabled by 3D interlocking structure is considered as the primary reinforcing mechanism for such superior properties. The smart composite design strategy should hold a place in developing future structural engineering materials. PMID:27135462

  18. Mutual inhibition of insulin signaling and PHLPP-1 determines cardioprotective efficiency of Akt in aged heart.

    Science.gov (United States)

    Xing, Yuan; Sun, Wanqing; Wang, Yishi; Gao, Feng; Ma, Heng

    2016-05-01

    Insulin protects cardiomyocytes from myocardial ischemia/reperfusion (MI/R) injury through activating Akt. However, phosphatase PHLPP-1 (PH domain leucine-rich repeat protein phosphatase-1) dephosphorylates and inactivates Akt. The balanced competitive interaction of insulin and PHLPP-1 has not been directly examined. In this study, we have identified the effect of mutual inhibition of insulin signaling and PHLPP-1 on the cardioprotective efficiency of Akt in aged heart. Young (3 months) and aged (20 months) Sprague Dawley (SD) rats were subjected to MI/Rin vivo. The PHLPP-1 level was higher in aged vs. young hearts at base. But, insulin treatment failed to decrease PHLPP-1 level during reperfusion in the aged hearts. Consequently, the cardioprotection of insulin-induced Akt activation was impaired in aged hearts, resulting in more susceptible to MI/R injury. In cultured rat ventricular myocytes, PHLPP-1 knockdown significantly enhanced insulin-induced Akt phosphorylation and reduced simulated hypoxia/reoxygenation-induced apoptosis. Contrary, PHLPP-1 overexpression terminated Akt phosphorylation and deteriorated myocytes apoptosis. Using in vivo aged animal models, we confirmed that cardiac PHLPP-1 knockdown or enhanced insulin sensitivity by exercise training dramatically increased insulin-induced Akt phosphorylation. Specifically, MI/R-induced cardiomyocyte apoptosis and infarct size were decreased and cardiac function was increased. More importantly, we found that insulin regulated the degradation of PHLPP-1 and insulin treatment could enhance the binding between PHLPP-1 and β-transducin repeat-containing protein (β-TrCP) to target for ubiquitin-dependent degradation. Altogether, we have identified a new mechanism by which insulin suppresses PHLPP-1 to enhance Akt activation. But, aged heart possesses lower insulin effectiveness and fails to decrease PHLPP-1 during MI/R, which subsequently limited Akt activity and cardioprotection. PHLPP-1 could be a

  19. Maternal Characteristics Determine Stunting in Children of Less than Five Years of Age Results from a National Probabilistic Survey

    Directory of Open Access Journals (Sweden)

    Teresa Shamah-Levy

    2008-01-01

    Full Text Available Background: Maternal nutrition and some variables are the main determining factors of birthweight and delayed intrauterine growth of children.Objective: To explore the association between the mothers’ biological and sociodemographic characteristics, and the anthropometry status in children under five years of age.Design: The population consisted of a sub-sample of 1,047 mother-and-child selected pairs from the probabilistic National Nutrition Survey, carried out in Mexico. Mother-and-child pairs included mothers aged 12 to 49 years, with children under five years of age. Data on sociodemographic characteristics, obstetric history, 24-hour recall dietary intake, and the women and children’s anthropometry were collected. The association between maternal characteristics and children’s anthropometry status was assessed using multiple logistic regression models.Result: Nearly 16.7% of the children 2y. The height/age of the children was severely affected by maternal height and birth order. In addition, the interaction between socioeconomic level and maternal schooling had a marginal effect (p = 0.09 in the ≤2y group. On the other hand, whether the family received social services and the interaction between maternal height and a dichotomy urbanism variable were significant ( p = 0.05 and (p 2y group.Conclusion: Some biological and socioeconomic characteristics among mothers have a negative effect on their children’s attained size, especially in the period between 2 and 5 years of age.

  20. Modeling the morphodynamic galectin patterning network of the developing avian limb skeleton.

    Science.gov (United States)

    Glimm, T; Bhat, R; Newman, S A

    2014-04-01

    We present a mathematical model for the morphogenesis and patterning of the mesenchymal condensations that serve as primordia of the avian limb skeleton. The model is based on the experimentally established dynamics of a multiscale regulatory network consisting of two glycan-binding proteins expressed early in limb development: CG (chicken galectin)-1A, CG-8 and their counterreceptors that determine the formation, size, number and spacing of the "protocondensations" that give rise to the condensations and subsequently the cartilaginous elements that serve as the templates of the bones. The model, a system of partial differential and integro-differential equations containing a flux term to represent local adhesion gradients, is simulated in a "full" and a "reduced" form to confirm that the system has pattern-forming capabilities and to explore the nature of the patterning instability. The full model recapitulates qualitatively and quantitatively the experimental results of network perturbation and leads to new predictions, which are verified by further experimentation. The reduced model is used to demonstrate that the patterning process is inherently morphodynamic, with cell motility being intrinsic to it. Furthermore, subtle relationships between cell movement and the positive and negative interactions between the morphogens produce regular patterns without the requirement for activators and inhibitors with widely separated diffusion coefficients. The described mechanism thus represents an extension of the category of activator-inhibitor processes capable of generating biological patterns with repetitive elements beyond the morphostatic mechanisms of the Turing/Gierer-Meinhardt type. PMID:24355216

  1. Aspects of the dosimetry of radionuclides within the skeleton with particular emphasis on the active marrow

    International Nuclear Information System (INIS)

    Epidemiological surveys on man and results from animal experiments have shown that two tissues associated with the skeleton are of primary concern with respect to cancer induction by ionizing radiation. These are the cells on or near endosteal surfaces of bone, from which osteosarcomas are thought to arise, and hematopoietic bone marrow, which is associated with leukemia. The complex geometry of the soft tissue-bone intermixture makes calculations of absorbed dose to these target regions a difficult problem. In the case of photon or neutron radiations, charged particle equilibrium may not exist in the vicinity of soft tissue-bone mineral interface. In this paper a general study of the dosimetry of radionuclides within the skeleton is presented. Dosimetric data consistent with the MIRD schema and reflecting the physical and anatomical parameters defining the energy deposition are tabulated for the relevant target regions. 27 refs., 5 figs., 5 tabs

  2. Aspects of the dosimetry of radionuclides within the skeleton with particular emphasis on the active marrow

    International Nuclear Information System (INIS)

    Epidemiological surveys on man and results from animal experiments have shown that two tissues associated with the skeleton are of primary concern with respect to cancer induction by ionizing radiation. These are the cells on or near endosteal surfaces of bone, from which osteosarcomas are thought to arise, and hematopoietic bone marrow, which is associated with leukemia. The complex geometry of the soft tissue-bone intermixture makes calculations of absorbed dose to these target regions a difficult problem. In the case of photon or neutron radiations, charged particle equilibrium may not exist in the vicinity of soft tissue-bone mineral interface. In this paper a general study of the dosimetry of radionuclides within the skeleton is presented. Dosimetric data consistent with the MIRD schema and reflecting the physical and anatomical parameters defining the energy deposition are tabulated for the relevant target regions. 27 references, 5 figures, 5 tables

  3. Hybrid Compounds Strategy in the Synthesis of Oleanolic Acid Skeleton-NSAID Derivatives

    Directory of Open Access Journals (Sweden)

    Anna Pawełczyk

    2016-04-01

    Full Text Available The current study focuses on the synthesis of several hybrid individuals combining a natural oleanolic acid skeleton and synthetic nonsteroidal anti-inflammatory drug moieties (NSAIDs. It studied structural modifications of the oleanolic acid structure by use of the direct reactivity of hydroxyl or hydroxyimino groups at position C-3 of the triterpenoid skeleton with the carboxylic function of anti-inflammatory drugs leading to new perspective compounds with high potential pharmacological activities. Novel ester- and iminoester-type derivatives of oleanolic unit with the different NSAIDs, such as ibuprofen, aspirin, naproxen, and ketoprofen, were obtained and characterized. Moreover, preliminary research of compounds obtaining structure stability under acidic conditions was examined and the PASS method of prediction of activity spectra for substances was used to estimate the potential biological activity of these compounds.

  4. Hybrid Compounds Strategy in the Synthesis of Oleanolic Acid Skeleton-NSAID Derivatives.

    Science.gov (United States)

    Pawełczyk, Anna; Olender, Dorota; Sowa-Kasprzak, Katarzyna; Zaprutko, Lucjusz

    2016-01-01

    The current study focuses on the synthesis of several hybrid individuals combining a natural oleanolic acid skeleton and synthetic nonsteroidal anti-inflammatory drug moieties (NSAIDs). It studied structural modifications of the oleanolic acid structure by use of the direct reactivity of hydroxyl or hydroxyimino groups at position C-3 of the triterpenoid skeleton with the carboxylic function of anti-inflammatory drugs leading to new perspective compounds with high potential pharmacological activities. Novel ester- and iminoester-type derivatives of oleanolic unit with the different NSAIDs, such as ibuprofen, aspirin, naproxen, and ketoprofen, were obtained and characterized. Moreover, preliminary research of compounds obtaining structure stability under acidic conditions was examined and the PASS method of prediction of activity spectra for substances was used to estimate the potential biological activity of these compounds. PMID:27077841

  5. Anatomo-radiographic description of the axial skeleton of the crab-eating fox (Cerdocyon thous

    Directory of Open Access Journals (Sweden)

    Janaína D. Barisson

    2012-12-01

    Full Text Available The aim of this study was to describe the axial skeleton of a wild Brazilian carnivorous, the crab-eating fox (Cerdocyon thous. Five specimens of crab-eating fox were previously unfrozen for radiographic exams and their bones went through dissection and chemical maceration. This animal presents seven cervical vertebrae, and from the third on, they become shorter and wider than the other ones e the spinous process was makeable from the fifth cervical vertebrae on. There are thirteen thoracic vertebrae and the spinous process of the lumbar vertebrae, which are seven, decreases from the fifth on. The sacrum is formed by two vertebrae and there are twenty or twenty one caudal vertebrae. It can be concluded that the crab-eating fox axial skeleton is similar to that of the domestic dog.

  6. Mobile computation offloading architecture for mobile augmented reality, case study: Visualization of cetacean skeleton

    Directory of Open Access Journals (Sweden)

    Belen G. Rodriguez-Santana

    2016-01-01

    Full Text Available Augmented Reality applications can serve as teach-ing tools in different contexts of use. Augmented reality appli-cation on mobile devices can help to provide tourist information on cities or to give information on visits to museums. For example, during visits to museums of natural history, applications of augmented reality on mobile devices can be used by some visitors to interact with the skeleton of a whale. However, making rendering heavy models can be computationally infeasible on devices with limited resources such as smart phones or tablets. One solution to this problem is to use techniques to Mobile Computation Offloading. This work proposes a mobile computation offloading architecture for mobile augmented reality. This solution would allow users to interact with a whale skeleton through an augmented reality application on mobile devices. Finally testing to assess the optimization of the resources of the mobile device when performing heavy render tests were made.

  7. Age determination and development of experimental methods for quaternary fault and formation

    International Nuclear Information System (INIS)

    Late cretaceous to early tertiary movement ages were constrained by Rb-Sr and K-Ar dating of fault rocks near the Uljin Nuclear Power Plants. These ages are well reproducible and consistent with geologic context. Tectonic evolution of the northeastern Yeongnam massif, the site of the Uljin Nuclear Power Plants, was investigated on the basis of Rb-Sr, Sm-Nd and Pb isotopic systematics and geochemistry of precambrian basement rocks including the Hosanri Formation, Buncheon granite gneiss, biotite granite gneiss, and Hongjesa granite. The optical ages from the Suryum fault outcrop represent the younger limit of sedimentation timing because they are simply based upon the present-day water content. The lower, Qt2 terrace at about 18m elevation is correlated with Marine Isotopic Stage (MIS) 5a, although its apparent optical age was consistently reported from 71 to 48 ka. Correlation of shoreline elevations indicates the correspondence of the Qt3a terrace to MIS 5e, which is supported by stratigraphically concordant optical ages for aeolian sand dunes at the north of the Suryum site. This time scale yields an uplift rate of 0.266 m/ka, requiring the revision of conventional view that the Korean peninsula is tectonically very stable

  8. Age determination and development of experimental methods for quaternary fault and formation

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Kwang Sik; Choi, M. S.; Kim, J. M. [Korea Basic Science Institute, Daejeon (Korea, Republic of)] (and others)

    2004-02-15

    Late cretaceous to early tertiary movement ages were constrained by Rb-Sr and K-Ar dating of fault rocks near the Uljin Nuclear Power Plants. These ages are well reproducible and consistent with geologic context. Tectonic evolution of the northeastern Yeongnam massif, the site of the Uljin Nuclear Power Plants, was investigated on the basis of Rb-Sr, Sm-Nd and Pb isotopic systematics and geochemistry of precambrian basement rocks including the Hosanri Formation, Buncheon granite gneiss, biotite granite gneiss, and Hongjesa granite. The optical ages from the Suryum fault outcrop represent the younger limit of sedimentation timing because they are simply based upon the present-day water content. The lower, Qt{sub 2} terrace at about 18m elevation is correlated with Marine Isotopic Stage (MIS) 5a, although its apparent optical age was consistently reported from 71 to 48 ka. Correlation of shoreline elevations indicates the correspondence of the Qt{sub 3a} terrace to MIS 5e, which is supported by stratigraphically concordant optical ages for aeolian sand dunes at the north of the Suryum site. This time scale yields an uplift rate of 0.266 m/ka, requiring the revision of conventional view that the Korean peninsula is tectonically very stable.

  9. Determining gestational age based on information from the Birth in Brazil study.

    Science.gov (United States)

    Pereira, Ana Paula Esteves; Leal, Maria do Carmo; da Gama, Silvana Granado Nogueira; Domingues, Rosa Maria Soares Madeira; Schilithz, Arthur Orlando Corrêa; Bastos, Maria Helena

    2014-08-01

    This study aimed at assessing the validity of different measures for estimating gestational age and to propose the creation of an algorithm for gestational age at birth estimates for the Birth in Brazil survey--a study conducted in 2011-2012 with 23,940 postpartum women. We used early ultrasound imaging, performed between 7-20 weeks of gestation, as the reference method. All analyses were performed stratifying by payment of maternity care (public or private). When compared to early ultrasound imaging, we found a substantial intraclass correlation coefficient of ultrasound-based gestational age at admission measure (0.95 and 0.94) and of gestational age reported by postpartum women at interview measure (0.90 and 0.88) for the public and private payment of maternity care, respectively. Last menstrual period-based measures had lower intraclass correlation coefficients than the first two measures evaluated. This study suggests caution when using the last menstrual period as the first measure for estimating gestational age in Brazil, strengthening the use of information obtained from early ultrasound imaging results. PMID:25167191

  10. Post-processing techniques for making reliable measurements from curve-skeletons.

    Science.gov (United States)

    Bradley, Robert S; Withers, Philip J

    2016-05-01

    Interconnected 3-D networks occur widely in biology and the geometry of such branched networks can be described by curve-skeletons, allowing parameters such as path lengths, path tortuosities and cross-sectional thicknesses to be quantified. However, curve-skeletons are typically sensitive to small scale surface features which may arise from noise in the imaging data. In this paper, new post-processing techniques for curve-skeletons are presented which ensure that measurements of lengths and thicknesses are less sensitive to these small scale surface features. The techniques achieve sub-voxel accuracy and are based on a minimal sphere-network representation in which the object is modelled as a string of minimally overlapping spheres, and as such samples the object on a scale related to the local thickness. A new measure of cross-sectional dimension termed the modal radius is defined and shown to be more robust in comparison with the standard measure (the internal radius), while retaining the desirable feature of capturing the size of structures in terms of a single measure. The techniques are demonstrated by application to trabecular bone and tumour vascular network case studies where the volumetric data was obtained by high resolution computed tomography. PMID:27035863

  11. Hardening of aged duplex stainless steels by spinodal decomposition.

    Science.gov (United States)

    Danoix, F; Auger, P; Blavette, D

    2004-06-01

    Mechanical properties, such as hardness and impact toughness, of ferrite-containing stainless steels are greatly affected by long-term aging at intermediate temperatures. It is known that the alpha-alpha' spinodal decomposition occurring in the iron-chromium-based ferrite is responsible for this aging susceptibility. This decomposition can be characterized unambiguously by atom probe analysis, allowing comparison both with the existing theories of spinodal decomposition and the evolution of some mechanical properties. It is then possible to predict the evolution of hardness of industrial components during service, based on the detailed knowledge of the involved aging process. PMID:15233853

  12. Hydrochemical modelling and determination of 14C ages of geothermal waters in Kizildere and Tekkehamam fields

    International Nuclear Information System (INIS)

    Many geothermal fluids are encountered as springs and wells in the area between Buharkent - Yenice - Pamukkale located in the Aegean Region to the east of the Bueyuek Menderes Graben. This study, constituting a part of the project called 'Age and Origin Determination of the High Temperature Geothermal Fluids in the Bueyuek Menderes Graben' and directed by the MTA General Directorate, aims the recharge and circulation period verification of related resources by means of interpreting isotopic and hydrochemical data of the above mentioned region. For this purpose, water chemistry, δ18O, δ2H, δ3H, 14C, δ34S-SO4 ve δ18O-SO4 isotope sampling have been realized in order to determine the geochemical processes taken place in underground. As a result of the study the origin, the recharge altitudes and the circulation periods of grouped fluids with temperatures between 35 degrees- 242 degreeslocated in the region were clarified. According to the given chemical data, hydrochemically characterized waters are classified in 10 different types. It has been indicated that, six subtypes of the classification are constituted from the mixtures of waters at 242 degreesand 4th type Na-HCO3 belonging to Kizildere thermal waters, first type Ca-HCO3 waters, second type Ca-HCO3-SO4 waters and third type Ca-SO4 waters. According to the evaluation of the 14C isotope, the geothermal fluid discharging from the Kizildere Power Plant, corresponds to a turnovertime of 22.500 - 27.500 years. Previous studies reveal that the waters of the Tekkehamam geothermal field originate from the mixture of shallow groundwaters encountered in the site with geothermal fluids underflowing from the Kizildere geothermal field, in north-south direction. Taken into consideration this mentioned mixture model, the 14C isotope indicates a turnovertime of 31.000 years for R-1 geothermal well and 35.000 years for the нnatlм spring, located in the Tekkehamam geothermal field

  13. A Skeleton for Distributed Work Pools in Eden

    DEFF Research Database (Denmark)

    Dieterle, Mischa; Berthold, Jost; Loogen, Rita

    2010-01-01

    worker processes. The latter are arranged in a ring topology and exchange additional channels to shortcut communication paths. The skeleton is suited for different types of algorithms, namely simple data parallel ones and standard tree search algorithms like backtracking, and using a global state as...

  14. Morphological analysis of mouse skeleton following AZD4547 treatment

    Czech Academy of Sciences Publication Activity Database

    Dosedělová, Hana; Veselá, Iva; Krejčí, P.; Kunová, M.; Buchtová, Marcela

    2015-01-01

    Roč. 159, Suppl 1 (2015), s. 58-59. ISSN 1213-8118. [Morphology 2015. International Congress of the Czech Anatomical Society /49./. Lojda Symposium on Histochemistry /52./. 06.09.2015-08.09.2015, Olomouc] R&D Projects: GA ČR(CZ) GA14-31540S Institutional support: RVO:67985904 Keywords : mouse skeleton Subject RIV: EA - Cell Biology

  15. A vanished history of skeletonization in Cambrian comb jellies

    OpenAIRE

    Ou, Qiang; Xiao, Shuhai; Han, Jian; Sun, Ge; Zhang, Fang; Zhang, Zhifei; Shu, Degan

    2015-01-01

    Ctenophores are traditionally regarded as “lower” metazoans, sharing with cnidarians a diploblastic grade of organization. Unlike cnidarians, where skeletonization (biomineralization and sclerotization) evolved repeatedly among ecologically important taxa (for example, scleractinians and octocorals), living ctenophores are characteristically soft-bodied animals. We report six sclerotized and armored ctenophores from the early Cambrian period. They have diagnostic ctenophore features (for exam...

  16. Identification through osteometric data on three radium-burdened skeletons

    International Nuclear Information System (INIS)

    The skeletal remains of four persons of uncertain identity were disinterred from a family grave. The weight and description morphological traits of each bone were recorded, as were the lengths of the long bones. Analyses of these data, combined with information obtained from medical records and disinterment reports, led to the specific identification of each skeleton

  17. Determination of the standard values of the hand bone mineral density values in males according to ages

    Directory of Open Access Journals (Sweden)

    Şule Temiztürk

    2013-01-01

    Full Text Available Objective: In this study we purposed to determine standardvalues of hand Bone Mineral Density (BMD accordingto ages by Dual Energy X-Ray Absorptiometry (DXAin males who applied to our hospital, evaluate associationof hand BMD with lumbar and femur BMD and searchusefulness of hand BMD measurement by DXA.Methods: Totally, 239 male included, whose ages differbetween 27 to 87 years, had no disease associatedwith bone density were included. The cases, betweenthe ages 20 to 70 separated to age groups, comprisedof 5 years. Cases, whose age is 70 and older, included inthe same group. Average of dominant and nondominanthand BMD values of the chosen cases were computedaccording to age groups comprised of 5 years and theassociation with values of L2-L4 and femur neck BMD issearched separately.Results: There is significant association between dominanthand BMD scores with L2-L4 and femur neck BMDscores. Also there is significant association between nondominanthand BMD scores with L2-L4 and femur neckBMD scores. Also there is asignificant association betweenscores of hand BMD with hand grip strenght.Conclusion: In this study there is significant associationbetween BMD scores of dominant and nondominanthand with BMD scores of L2-L4 and femur neck in all agegroups. Rheumatological diseases, reflex sympatheticdystrophy, tendon and nerve lacerations of hand and forearm,fractures of upper extremity and hemiplegy, that cancauses local osteoporosis in the hand, measurement ofhand BMD can be done by DXA.Key words: Bone mineral density, dual energy X ray absorptiometry,osteoporosis

  18. 3-D-CT reconstructions in fractures of the skull base and facial skeleton

    International Nuclear Information System (INIS)

    3-D reconstructions of the skull base, temporal bone, and skull fractures were compared to 2-D CT to evaluate the diagnostic value in traumatized patients. 38 patients with 22 fractures of the facial skeleton (orbita, zygomatic, Le Fort), 12 temporal bone, and 4 skull fractures were investigated. Subjective grading was perfomed by two physicians (ENT/RAD) in respect of quality diagnostic validity and estimated clinical impact. The average image validity and quality were graded good. In the temporal bone the average information supplied by 3-D was of inferior value; here, the lack of information regarding the inner ear structures was responsible for the lack of clinical impact. In fractures of the facial skeleton and the skull base of good to very good image quality was seen and clinical relevance was high. 3-D CT is capable of demonstrating fractures, which is of little value in the temporal bone, but of high value in the skull base and the facial skeleton, especially if surfaces are involved or fragments are displaced. (orig.)

  19. Patterns of morphological integration in the appendicular skeleton of mammalian carnivores.

    Science.gov (United States)

    Martín-Serra, Alberto; Figueirido, Borja; Pérez-Claros, Juan Antonio; Palmqvist, Paul

    2015-02-01

    We investigated patterns of evolutionary integration in the appendicular skeleton of mammalian carnivores. The findings are discussed in relation to performance selection in terms of organismal function as a potential mechanism underlying integration. Interspecific shape covariation was quantified by two-block partial least-squares (2B-PLS) analysis of 3D landmark data within a phylogenetic context. Specifically, we compared pairs of anatomically connected bones (within-limbs) and pairs of both serially homologous and functional equivalent bones (between-limbs). The statistical results of all the comparisons suggest that the carnivoran appendicular skeleton is highly integrated. Strikingly, the main shape covariation relates to bone robustness in all cases. A bootstrap test was used to compare the degree of integration between specialized cursorial taxa (i.e., those whose forelimbs are primarily involved in locomotion) and noncursorial species (i.e., those whose forelimbs are involved in more functions than their hindlimb) showed that cursors have a more integrated appendicular skeleton than noncursors. The findings demonstrate that natural selection can influence the pattern and degree of morphological integration by increasing the degree of bone shape covariation in parallel to ecological specialization. PMID:25403786

  20. Characterization of rhenium compounds obtained by electrochemical synthesis after aging process

    International Nuclear Information System (INIS)

    The proper identification of the molecular nature of the aged rhenium compound obtained by means of electrodeposition from an alkaline aqueous electrolyte was determined. Chemical, structural and vibrational experimental characterization of the aged Re compound showed agreement with quantum-computations, thereby allowing the unambiguous identification of the Re compound as H(ReO4)H2O. - Graphical abstract: Rhenium oxides were electrodeposited on a copper surface and after environmental aging was formed the H(ReO4)H2O compound. The characterization of the synthesized material was made through the comparison of experimental evidence with quantum mechanical computations carried out by means of density functional theory (DFT). - Highlights: • Aged rhenium compound obtained by means of electrodeposition was studied. • The study was made by combining experimental and DFT-computational information. • The aged electrodeposited material is consistent with the H(ReO4)H2O compound

  1. Lifetime estimation of zirconia ceramics by linear ageing kinetics

    International Nuclear Information System (INIS)

    Up to now, the ageing kinetics of zirconia ceramics were mainly derived from the sigmoidal evolution of the surface phase transformation as a function of time, as quantified by means of X-ray diffraction (XRD). However, the transformation propagation into the material should be better to monitor the ageing kinetics. In this work, μ-Raman spectroscopy was used to quantitatively measure the transformation profiles in depth as a function of ageing time at 160 °C, 140 °C, 134 °C and 110 °C. A linear relationship between the transformed depth and the ageing time was observed for all investigated yttria stabilized tetragonal zirconia polycrystals (3Y-TZP). Furthermore, the μ-Raman investigation of residual stresses in the subsurface of aged 3Y-TZPs showed that the highest tensile stress was located just ahead of the transformation front, indicating the key responsibility of stress accumulation for transformation front propagating into the material. Moreover, the linear kinetics of the transformation propagation were more accurate to calculate the apparent activation energy of the ageing process and allowed a more straightforward estimation of the lifetime of 3Y-TZP at body temperature, as compared to the conventional ageing kinetic parameters obtained from the surface transformation analysis by XRD

  2. Study on pressure resistance spot welding process of guide thimble and grid of AFA 3G advanced fuel assembly skeleton

    International Nuclear Information System (INIS)

    Skeleton spot welding is an important process of manufacturing PWR fuel assembly. In AFA 3G Skeleton spot welding, the pressure resistant spot welding technology of grid and variable thickness guide thimble is a new technical problem. By means of a lot of experiments, it is discussed in detail how different welding parameters impact on weld quality. Welding parameters impact on welding spots tensile force, welding spots diameter and welding spots corrosion performance. Analyzing and comparing with test data can get better welding parameters

  3. Psychosocial determinants of contraceptive use among women of reproductive age in a rural area of Maharashtra

    Directory of Open Access Journals (Sweden)

    Minhas S, Sekhon H

    2014-03-01

    Full Text Available The World Health Organisation reports that an estimated 94 per cent of the population of the world lives in countries with policies that favour family planning. Despite this, five of every six couples of reproductive age do not use adequate measures of fertility regulation. Gender inequalities in patriarchal societies ensure that men play a critical role in the decisions on family matters. The present study was undertaken to study the nature of acceptance of contraceptive practices and the psychosocial determinants. Methods: This was a community based cross sectional descriptive study. The anticipated prevalence of contraceptive practices among the 206 women in the age group of 15-49 years was 50%. Considering a margin of error of 10%, with finite correction and 10% of non-response and 95% CI, the sample size was calculated. 90 married women in the reproductive age group of 15-49 years residing at the village were studied after drawing the sample with simple random sampling method. Results: There were 55 (61.11% women who practised contraception. In case of 03 (3.33% couples, husbands used condoms, while in case of remaining 52 (57.78%, wife had undergone tubectomy. Conclusion: From the present study, it was concluded that the most common method of contraception practiced in the study population was tubectomy and a range of psychosocial factors played an important role in decision making.

  4. Groundwater arsenic concentrations in Vietnam controlled by sediment age

    DEFF Research Database (Denmark)

    Postma, Dieke; Larsen, Flemming; Thai, Nguyen Thi; Trang, Pham Thi Kim; Jakobsen, Rasmus; Nhan, Pham Quy; Long, Tran Vu; Viet, Pham Hung; Murray, Andrew Sean

    2012-01-01

    Arsenic contamination of groundwater continues to threaten the health of millions of people in southeast Asia. The oxidation of organic carbon, coupled to the reductive dissolution of arsenic-bearing iron oxides, is thought to control the release of sediment-bound arsenic into groundwater. However......, the cause of the high spatial variability in groundwater arsenic concentrations—which can range from 5 to 500 μg l−1 within distances of a few kilometres—has been uncertain. Here, we combine measurements of sediment age, organic-matter reactivity and water chemistry at four locations along a cross......-section of the arsenic-contaminated Red River floodplain in Vietnam to determine the origin of variations in groundwater arsenic concentrations. The burial age of the aquifer sediments, determined using optical stimulated luminescence, ranged from 460 years near the course of the present-day river to 5...

  5. Obsidian ages from Ecuador by the fission track dating

    International Nuclear Information System (INIS)

    Fission track dating was applied in order to study obsidian samples originated from Mullumica and Callejones flows, Oyacachi, Ecuador. Preliminary data show that the ratio between the mean diameter os spontaneous and induced tracks is about 0.9, an indication that the analysed samples were submitted to small fading during their geological histories. Ages were obtained around 0.2 x 106a, in agreement with Miller and Wagners's results. Ages ranging from 0.17 x 106a up to 0.23 x 106a were obtained correcting the apparent ages by means of the plateau method. (author)

  6. Pharmacokinetic modelling of multi-decadal luminescence time series in coral skeletons

    Science.gov (United States)

    Llewellyn, Lyndon E.; Everingham, Yvette L.; Lough, Janice M.

    2012-04-01

    As corals grow, they incorporate chemical indicators of seawater conditions into their aragonite skeleton after they have traversed an outer living tissue layer. Long-lived, massive coral skeletons can record decade- and century-long time series of seawater status. One such environmental clue is luminescence intensity which can correspond to river flow patterns and has been attributed to humic acid incorporation. Seawater humic acid levels are linked to river flow as rainfall extracts them from catchment soils to then flow into rivers and coastal seas. However, discrepancies exist when validating coral luminescence records against river flow data with intense luminescence sometimes occurring in the absence of increased flows. This contributes to uncertainty when reconstructing pre-instrumental river flows and rainfall from coral luminescence. Here we demonstrate that a major portion of coral core luminescence time series can be explained using a single-compartment, pharmacokinetic model that incorporates river flow measurements as the equivalent of drug dose. The model was robust for luminescence series in corals from near-shore reefs regularly influenced by river flow. The model implies that after floods, a proportion of subsequent luminescence peaks can be derived from the initial flood. This explains why some luminescence peaks after floods often do not correspond to additional significant river flows. This provides the first mechanism-based explanation for temporal changes in coral skeleton luminescence that incorporates a mathematical link between two independent time series making this proxy even more robust for reconstructing river flow and rainfall.

  7. Validation of anti-aging drugs by treating age-related diseases

    OpenAIRE

    Blagosklonny, Mikhail V.

    2009-01-01

    Humans die from age-related diseases, which are deadly manifestations of the aging process. In order to extend life span, an anti-aging drug must delay age-related diseases. All together age-related diseases are the best biomarker of aging. Once a drug is used for treatment of any one chronic disease, its effect against other diseases (atherosclerosis, cancer, prostate enlargement, osteoporosis, insulin resistance, Alzheimer's and Parkinson's diseases, age-related macular degeneration) may be...

  8. Growth rates and ages of deep-sea corals impacted by the Deepwater Horizon oil spill

    Science.gov (United States)

    Prouty, Nancy G.; Fisher, Charles R.; Demopoulos, Amanda W. J.; Druffel, Ellen R. M.

    2016-01-01

    The impact of the April 2010 Deepwater Horizon (DWH) spill on deep-sea coral communities in the Gulf of Mexico (GoM) is still under investigation, as is the potential for these communities to recover. Impacts from the spill include observation of corals covered with flocculent material, with bare skeleton, excessive mucous production, sloughing tissue, and subsequent colonization of damaged areas by hydrozoans. Information on growth rates and life spans of deep-sea corals is important for understanding the vulnerability of these ecosystems to both natural and anthropogenic perturbations, as well as the likely duration of any observed adverse impacts. We report radiocarbon ages and radial and linear growth rates based on octocorals (Paramuricea spp. and Chrysogorgia sp.) collected in 2010 and 2011 from areas of the DWH impact. The oldest coral radiocarbon ages were measured on specimens collected 11 km to the SW of the oil spill from the Mississippi Canyon (MC) 344 site: 599 and 55 cal yr BP, suggesting continuous life spans of over 600 years for Paramuricea biscaya, the dominant coral species in the region. Calculated radial growth rates, between 0.34 μm yr−1 and 14.20 μm yr−1, are consistent with previously reported proteinaceous corals from the GoM. Anomalously low radiocarbon (Δ14C) values for soft tissue from some corals indicate that these corals were feeding on particulate organic carbon derived from an admixture of modern surface carbon and a low 14C carbon source. Results from this work indicate fossil carbon could contribute 5–10% to the coral soft tissue Δ14C signal within the area of the spill impact. The influence of a low 14C carbon source (e.g., petro-carbon) on the particulate organic carbon pool was observed at all sites within 30 km of the spill site, with the exception of MC118, which may have been outside of the dominant northeast-southwest zone of impact. The quantitatively assessed extreme longevity and slow growth rates documented

  9. An Interactive Exhibition about Animal Skeletons: Did the Visitors Learn Any Zoology?

    Science.gov (United States)

    Tunnicliffe, Sue Dale; Laterveer-de Beer, Manon

    2002-01-01

    Explores museum visitors' understanding of skeleton exhibits and whether such exhibits increase their understanding of the zoology displayed. The exhibition under study focused on the diversity of vertebrae skeletons which were arranged according to the mode of locomotion. (DDR)

  10. Forensic Medicine: Age Written in Teeth by Nuclear Bomb Tests

    Energy Technology Data Exchange (ETDEWEB)

    Lawrence Livermore National Laboratory

    2005-05-04

    Establishing the age of individuals is an important step in identification and a frequent challenge in forensic medicine. This can be done with high precision up to adolescence by analysis of dentition, but establishing the age of adults has remained difficult. Here we show that measuring {sup 14}C from nuclear bomb tests in tooth enamel provides a sensitive way to establish when a person was born.

  11. Determination of reddening and age for ten Large Magellanic Cloud star clusters from integrated spectroscopy

    CERN Document Server

    Ahumada, Andrea V; Clariá, Juan J; Oddone, Mónica A; Palma, Tali

    2016-01-01

    We present flux-calibrated integrated spectra in the optical range (3700-6800 \\AA) obtained at Complejo Astron\\'omico El Leoncito (CASLEO, Argentina) for a sample of 10 concentrated star clusters belonging to the Large Magellanic Cloud (LMC). No previous data exist for two of these objects (SL 142 and SL 624), while most of the remaining clusters have been only poorly studied. We derive simultaneously foreground $E(B-V)$ reddening values and ages for the cluster sample by comparing their integrated spectra with template LMC cluster spectra and with two different sets of simple stellar population models. Cluster reddening values and ages are also derived from both available interstellar extinction maps and by using diagnostic diagrams involving the sum of equivalent widths of some selected spectral features and their calibrations with age, respectively. For the studied sample, we derive ages between 1 Myr and 240 Myr. In an effort to create a spectral library at the LMC metallicity level with several clusters ...

  12. [Age-related post-translational modification of proteins in human tissue and its use determination of age in forensic medicine. Review].

    Science.gov (United States)

    Pilin, A; Pudil, F; Sajdok, J; Zídková, J; Bezdícková, D; Bencko, V

    2003-10-01

    This article deals with some of posttranslational modification of proteins which are, or could be useful to work out objective and standard methods for age estimation in forensic medicine. From many posttranslational modifications other than racemization, the evaluation of pentosidine, one of the products of nonenzymatic glycosylation, seems to be promising. The enlargement of menu of methods for age estimation is important mainly for forensic sciences when determination of the age of an unknown dead body is necessary. Morphological methods are quite often subjective and charged with errors. PMID:14661529

  13. Stable isotopic records of bleaching and endolithic algae blooms in the skeleton of the boulder forming coral Montastraea faveolata

    OpenAIRE

    Hartmann, A.C.; Carilli, J. E.; Norris, R. D.; Charles, C. D.; Deheyn, D. D.

    2010-01-01

    Within boulder forming corals, fixation of dissolved inorganic carbon is performed by symbiotic dinoflagellates within the coral tissue and, to a lesser extent, endolithic algae within the coral skeleton. Endolithic algae produce distinctive green bands in the coral skeleton, and their origin may be related to periods of coral bleaching due to complete loss of dinoflagellate symbionts or ‘‘paling’’ in which symbiont populations are patchily reduced in coral tissue. Stable carbon isotopes were...

  14. Long-term loss of radium in 63 subjects first exposed at ages 6 to 46

    International Nuclear Information System (INIS)

    The absorbed dose to bone following the deposition of radium in the skeleton is principally determined by its long-term rate of clearance. In mice, rats, and dogs injected with alkaline-earth radionuclides at various ages between puberty and young adulthood, a negative correlation was observed between the age at injection and the skeletal uptake of the radionuclide and, at short times after injection, a positive correlation was observed between the age at injection and the fraction of the contemporary body content of the radionuclide excreted per unit of time, whereas at long times after injection the fractional clearance rate was found to be largely independent of the age at injection. Age-dependent models of radium retention proposed for man conform to the metabolic observations in animals in their assumption that at long times after intake the fraction of the contemporary body content of radium excreted per unit of time is independent of the age at intake. In this paper, we investigate whether this assumption is supported by the data on the long-term retention of radium in radium-exposed persons

  15. Precise determination of uranium by extraction spectrophotometry

    International Nuclear Information System (INIS)

    In the conventional method of potentiometric titration, the concentration of potassium dichromate solution was optimized with selection of different concentrations of the solution. The electrode responded slowly during the titration procedure, thus affected the precision and accuracy of the results. An extraction spectrophotometric method for accurate and precise determination of uranium was presented. The method was based on the extraction of Cr (VI)-diphenylcarbazide purple complex using iso-amyl alcohol as the extractant. The purple complex was directly measured at 546 nm so that the uranium-chromate equivalence point can be determined. A method for precise determining uranium by extraction spectrophotometry was developed. The China national reference material of U3O8 (GBW04205) was determined according to the optimized experimental conditions. The relative standard deviation is 0.025% and accuracy of the method is verified by the value of China national reference material of U3O8. (authors)

  16. A Robust Rigid Skeleton Extraction Method from Noisy Visual Hull Model

    OpenAIRE

    Xiaojun Wu; YiXin Xu

    2015-01-01

    The existing skeleton extraction algorithms from a coarse and noisy model cannot achieve a satisfactory skeleton, let alone the joints’ central position in a markerless motion capture system (e.g., a rigid skeleton). To solve this problem, we propose a rigid skeleton extraction algorithm from a noisy visual hull model with phantom volumes. Firstly, we reconstruct the subject visual hull and the corresponding volumetric model from a multiple-view synchronized video sequence. Secondly, the curv...

  17. Dressed skeleton expansion and the coupling scale ambiguity problem

    Energy Technology Data Exchange (ETDEWEB)

    Lu, Hung Jung

    1992-09-01

    Perturbative expansions in quantum field theories are usually expressed in powers of a coupling constant. In principle, the infinite sum of the expansion series is independent of the renormalization scale of the coupling constant. In practice, there is a remnant dependence of the truncated series on the renormalization scale. This scale ambiguity can severely restrict the predictive power of theoretical calculations. The dressed skeleton expansion is developed as a calculational method which avoids the coupling scale ambiguity problem. In this method, physical quantities are expressed as functional expansions in terms of a coupling vertex function. The arguments of the vertex function are given by the physical momenta of each process. These physical momenta effectively replace the unspecified renormalization scale and eliminate the ambiguity problem. This method is applied to various field theoretical models and its main features and limitations are explored. For quantum chromodynamics, an expression for the running coupling constant of the three-gluon vertex is obtained. The effective coupling scale of this vertex is shown to be essentially given by {mu}{sup 2} {approximately} Q{sub min}{sup 2}Q{sub med}{sup 2}/Q{sub max}{sup 2} where Q{sub min}{sup 2}Q{sub med}{sup 2}/Q{sub max}{sup 2} are respectively the smallest, the next-to-smallest and the largest scale among the three gluon virtualities. This functional form suggests that the three-gluon vertex becomes non-perturbative at asymmetric momentum configurations. Implications for four-jet physics is discussed.

  18. Orbit determination by range-only data.

    Science.gov (United States)

    Duong, N.; Winn, C. B.

    1973-01-01

    The determination of satellite orbits for use in geodesy using range-only data has been examined. A recently developed recursive algorithm for rectification of the nominal orbit after processing each observation has been tested. It is shown that when a synchronous satellite is tracked simultaneously with a subsynchronous geodetic target satellite, the orbits of each may be readily determined by processing the range information. Random data errors and satellite perturbations are included in the examples presented.

  19. The rules of implicit evaluation by race, religion, and age.

    Science.gov (United States)

    Axt, Jordan R; Ebersole, Charles R; Nosek, Brian A

    2014-09-01

    The social world is stratified. Social hierarchies are known but often disavowed as anachronisms or unjust. Nonetheless, hierarchies may persist in social memory. In three studies (total N > 200,000), we found evidence of social hierarchies in implicit evaluation by race, religion, and age. Participants implicitly evaluated their own racial group most positively and the remaining racial groups in accordance with the following hierarchy: Whites > Asians > Blacks > Hispanics. Similarly, participants implicitly evaluated their own religion most positively and the remaining religions in accordance with the following hierarchy: Christianity > Judaism > Hinduism or Buddhism > Islam. In a final study, participants of all ages implicitly evaluated age groups following this rule: children > young adults > middle-age adults > older adults. These results suggest that the rules of social evaluation are pervasively embedded in culture and mind. PMID:25079218

  20. Fingermark age determinations: Legal considerations, review of the literature and practical propositions.

    Science.gov (United States)

    Girod, A; Ramotowski, R; Lambrechts, S; Misrielal, P; Aalders, M; Weyermann, C

    2016-05-01

    The question of the age of fingermarks is often raised in investigations and trials when suspects admit that they have left their fingermarks at a crime scene but allege that the contact occurred at a different time than the crime and for legal reasons. In the first part of this review article, examples from American appellate court cases will be used to demonstrate that there is a lack of consensus among American courts regarding the admissibility and weight of testimony from expert witnesses who provide opinions about the age of fingermarks. Of course, these issues are not only encountered in America but have also been reported elsewhere, for example in Europe. The disparity in the way fingermark dating cases were managed in these examples is probably due to the fact that no methodology has been validated and accepted by the forensic science community so far. The second part of this review article summarizes the studies reported on fingermark dating in the literature and highlights the fact that most proposed methodologies still suffer from limitations preventing their use in practice. Nevertheless, several approaches based on the evolution of aging parameters detected in fingermark residue over time appear to show promise for the fingermark dating field. Based on these approaches, the definition of a formal methodological framework for fingermark dating cases is proposed in order to produce relevant temporal information. This framework identifies which type of information could and should be obtained about fingermark aging and what developments are still required to scientifically address dating issues. PMID:27044033

  1. Correlation of Condylar Guidance Determined by Panoramic Radiographs to One Determined by Conventional Methods

    OpenAIRE

    Godavarthi, A Sowjanya; Sajjan, M C Suresh; Raju, A V Rama; P RajeshKumar; Premalatha, Averneni; Chava, Narayana

    2015-01-01

    Background: To evaluate the feasibility of using panoramic radiographs as an alternative to an interocclusal recording method for determining the condylar guidance in dentate and edentulous conditions. Materials and Methods: 20 dentulous individuals with an age range of 20-30 years and 20 edentulous patients of 40-65 years were selected. An interocclusal bite registration was done in protrusive position for all the subjects. Orthopantomographs were made for all patients in open mouth position...

  2. Quantitative diagnosis of skeletons with demineralizing osteopathy

    International Nuclear Information System (INIS)

    The quantitative diagnosis of bone diseases must be assessed according to the accuracy of the applied method, the expense in apparatus, personnel and financial resources and the comparability of results. Nuclide absorptiometry and in the future perhaps computed tomography represent the most accurate methods for determining the mineral content of bones. Their application is the clinics' prerogative because of the costs. Morphometry provides quantiative information, in particular in course control, and enables an objective judgement of visual pictures. It requires little expenditure and should be combined with microradioscopy. Direct comparability of the findings of different working groups is most easy in morphometry; it depends on the equipment in computerized tomography and is still hardly possible in nuclide absorptiometry. For fundamental physical reason, it will hardly be possible to produce a low-cost, fast and easy-to-handle instrument for the determination of the mineral salt concentration in bones. Instead, there is rather a trend towards more expensive equipment, e.g. CT instruments; the universal use of these instruments, however, will help to promote quantitative diagnoses. (orig.)

  3. Age and gender as determinants of the bone quality of the greater tuberosity: A HR-pQCT cadaver study

    Directory of Open Access Journals (Sweden)

    Kirchhoff Chlodwig

    2012-11-01

    Full Text Available Abstract Background Age-dependent trabecular changes of the humeral head might weaken the fixation of suture anchors used for rotator cuff (RC repair. This might lead to suture anchor loosening and thus compromise the integrity of the repair. The aim of this study was to analyze whether the trabecular microstructure within the RC footprint is influenced by age, gender or handedness. Methods Axial HR-pQCT scans (Scanco Medical of 64 freshly frozen cadaveric human humeral head specimens (age 72.3 ± 17.4 years were analyzed to determine the bone volume-to-total volume ratio (BV/TV, trabecular thickness (Trab Th, trabecular number (Trab N and connectivity density (Conn Dens. Within the RC footprint, 2 volumes of interest (VOI, posteromedial (PM and anterolateral (AL and one control VOI in the subarticular bone (SC were set. Results The highest BV/TV was found in SC: 0.22 ± 0.06% vs. PM: 0.04 ± 0.05% vs. AL: 0.02 ± 0.04%; p  Conclusions The presented microarchitectural data allow for future subtle biomechanical testing comprising knowledge on age- and sex-related changes of the tuberosities of the humeral head. Furthermore, the insights on the trabecular structure of the humeral head of the elderly may lead to the development of new fixation materials in bone with inferior bone quality.

  4. Determinants of Anemia among Children Aged 6–59 Months Living in Kilte Awulaelo Woreda, Northern Ethiopia

    Directory of Open Access Journals (Sweden)

    Gebremedhin Gebreegziabiher

    2014-01-01

    Full Text Available Introduction. The aim of this study was to determine the prevalence of anemia and determinant factors among children aged 6–59 months living in Kilte Awulaelo Woreda, eastern zone. Method. A community based cross-sectional study was conducted during February 2013 among 6 tabias of Kilte Awulaelo Woreda, northern Ethiopia. A total of 568 children were selected by systematic random sampling method. Anthropometric data and blood sample were collected. Bivariate and multivariate logistic regression analyses were performed to identify factors related to anemia. Result. The mean hemoglobin level was 11.48 g/dl and about 37.3% of children were anemic. Children who were aged 6–23 months [AOR = 1.89: 95% CI (1.3, 2.8], underweight [AOR = 2.05: 95% CI (1.3, 3.3], having MUAC less than 12 cm [AOR = 3.35: 95% CI (2.1, 5.3], and from households with annual income below 10,000 Ethiopian birr [AOR = 4.86: 95% CI (3.2, 7.3] were more likely to become anemic. Conclusion. The prevalence of anemia among the children is found to be high. It was associated with annual household income, age, and nutritional status of the child. So, improving family income and increasing awareness of the mother/caregiver were important intervention.

  5. Age-Dependent Reductions in Mitochondrial Respiration are Exacerbated by Calcium in the Female Rat Heart

    OpenAIRE

    Hunter, J. Craig; Machikas, Alexandra M.; Korzick, Donna H.

    2012-01-01

    Cardiovascular disease mortality increases rapidly following menopause by poorly defined mechanisms. Since mitochondrial function and Ca2+ sensitivity are important regulators of cell death following myocardial ischemia, we sought to determine if aging and/or estrogen deficiency (ovx) increased mitochondrial Ca2+ sensitivity. Mitochondrial respiration was measured in ventricular mitochondria isolated from adult (6mo; n=26) and aged (24mo; n=25), intact or ovariectomized female rats using the ...

  6. Patch-type Segmentation of Voxel Shapes using Simplified Surface Skeletons

    NARCIS (Netherlands)

    Reniers, Dennie; Telea, Alexandru

    2008-01-01

    We present a new method for decomposing a 3D voxel shape into disjoint segments using the shape’s simplified surface-skeleton. The surface skeleton of a shape consists of 2D manifolds inside its volume. Each skeleton point has a maximally inscribed ball that touches the boundary in at least two cont

  7. New evolutionary sequences for extremely low mass white dwarfs: Homogeneous mass and age determinations, and asteroseismic prospects

    CERN Document Server

    Althaus, Leandro G; Córsico, Alejandro H

    2013-01-01

    We provide a fine and homogeneous grid of evolutionary sequences for He-core white dwarfs with masses 0.15-0.45 Msun, including the mass range for ELM white dwarfs (<0.20Msun). The grid is appropriate for mass and age determination, and to study their pulsational properties. White dwarf sequences have been computed by performing full evolutionary calculations that consider the main energy sources and processes of chemical abundance changes during white dwarf evolution. Initial models for the evolving white dwarfs have been obtained by computing the non-conservative evolution of a binary system consisting of a Msun ZAMS star and a 1.4 Msun neutron star for various initial orbital periods. To derive cooling ages and masses for He-core white dwarf we perform a least square fitting of the M(Teff, g) and Age(Teff, g) relations provided by our sequences by using a scheme that takes into account the time spent by models in different regions of the Teff-g plane. This is useful when multiple solutions for cooling a...

  8. Geomagnetic Investigation of Sandstone Dikes of the Colorado Front Range, for Determination of Age and Mode of Emplacement

    Science.gov (United States)

    Freedman, D.; Petronis, M. S.; Siddoway, C. S.

    2012-12-01

    In the Colorado Front Range, an array of sandstone dikes has intrigued geologists for over a century (Cross 1894,GSAB, 5, 525). Within their crystalline host, the dikes reach widths >7m and have a lateral extent of 70km along the Ute Pass Fault (UPF). The essential questions of sediment source, emplacement mode, and age of the dikes are unanswered. We present new paleomagnetic, rock magnetic, and anisotropy of magnetic susceptibility (AMS) results used to determine the age and emplacement behavior of the dikes. The eleven dikes selected for magnetic studies have sharp, planar margins, and share the systematic geometry of the NW striking subvertical dike array. They exhibit little or no overprint by brittle fracturing/shear associated with the UPF. Our approach involved the use of paleomagnetic techniques to isolate the characteristic remanent magnetization (ChRM), which we used to limit the age of the dikes' magnetization. Anisotropy of magnetic susceptibility (AMS),arising from alignment of detrital magnetite, serves as a proxy for the orientation of flow during dike emplacement. U-Pb detrital zircon ages, obtained previously, did not provide a useful constraint on emplacement age because the dominant age matches that of the prevalent host,1.03Ga Pikes Peak Granite. IRM acquisition experiments were performed to identify the principal magnetic phases as a mixture of Fe-Ti oxide phases, likely to be low-Ti magnetite and hematite. The sandstone consists of sub-rounded to rounded sand-sized quartz, angular feldspar (600°C. Some samples carry a characteristic remanent magnetization (ChRM) of NW declination with shallow positive inclination, while others yield a characteristic remanent magnetization of SE declination with shallow inclination. By correlation with paleomagnetic results from the region, our findings indicate an age Permian or older. The NW directed ChRM may signify a magnetization of Neoproterozoic age, while the SE directed ChRM is more consistent with a

  9. Non-stochastic effects of 226Ra and 228Ra in the human skeleton

    International Nuclear Information System (INIS)

    Results are reported of a comparative evaluation of the non-neoplastic changes that have been observed radiographically in the bones of two groups of former radium dial workers, one comprising 201 women exposed predominantly to 226Ra and the other comprising 159 women exposed predominantly to 228Ra at a median age of 18 years. The characteristic changes range through progressively larger and more frequent foci of both decreased and increased bone density (radiolucent and dense bone necrosis). Criteria developed in earlier studies were used to assign a numerical score to the changes seen in each individual. The score was used as a quantitative measure of bone necrosis. The long bones contributed the major portion of the total score for the skeleton, with the radii and ulnae showing the highest score on the basis of relative bone mass. The ribs and vertebrae, which account for 20% of the total bone mass, contributed 25 advanced degree of severity. At intakes of either radium isotope below 10 μCi, no changes above minimal were observed, and the mean score was about the same as the mean of about 0.2 observed in a group of 120 matched control subjects. At intakes below 100 μCi, mean scores per year post exposure were predicted by 0.0016 I, where I is the systemic intake in μCi of either 226Ra or 228Ra. For 50 year 226Ra or 228Ra workers with annual systemic intakes at the ICRP limit of about 0.4 μCi, the predicted mean score at about 50 years is 1.0. (author)

  10. Distribution of 241Am in the human body as determined by external counting

    International Nuclear Information System (INIS)

    Methods for determining the distribution of 241Am within the body of a contaminated subject and their application to several cases under study at the Center for Human Radiobiology are described. In general, 241Am is found in the lungs even at long times after inhalation, and systemic 241Am is observed to deposit in the liver and to label the skeleton in a fairly uniform manner; similar findings have been reported in animal studies (L172). Further analysis of the skeletal distribution of 241Am indicates deposition on bone surfaces. In contrast, the distribution of injected 239Pu in an (abnormal) skeleton is rather non-uniform when compared to that of 241Am

  11. Determination of U(IV) by spectrophotometry

    International Nuclear Information System (INIS)

    The determination of uranium (IV) concentration in acid solutions in the presence of U (IV), Fe (II) and Ti (IV) by spectrophotometry is studied, aiming at controlling the solutions in the ion exchange columns, used for uranium enrichment by isotope exchange. (E.G.)

  12. Determining The Effects Of Radiation On Aging Concrete Structures Of Nuclear Reactors

    International Nuclear Information System (INIS)

    The U.S. Department of Energy Office of Environmental Management (DOE-EM) is responsible for the Decontamination and Decommissioning (D and D) of nuclear facilities throughout the DOE Complex. Some of these facilities will be completely dismantled, while others will be partially dismantled and the remaining structure will be stabilized with cementitious fill materials. The latter is a process known as In-Situ Decommissioning (ISD). The ISD decision process requires a detailed understanding of the existing facility conditions, and operational history. System information and material properties are need for aged nuclear facilities. This literature review investigated the properties of aged concrete structures affected by radiation. In particular, this review addresses the Savannah River Site (SRS) isotope production nuclear reactors. The concrete in the reactors at SRS was not seriously damaged by the levels of radiation exposure. Loss of composite compressive strength was the most common effect of radiation induced damage documented at nuclear power plants.

  13. Evaluation of Anchovy (Engraulis encrasicolus Population by Age and Length

    Directory of Open Access Journals (Sweden)

    JERINA KOLITARI

    2014-03-01

    Full Text Available Anchovy (Engraulis enchrasicholus, is a member of small pelagic fish group in the waters of the Mediterranean and Adriatic Sea with important economic value for all regional countries, including Albania. The purpose of this study was to define the age of Anchovy, as one of the important indicators for the assessment of fishing reserves. Age evaluation was based on sagital otoliths, found in the inner ear of the fish. The study was conducted at the Aquaculture and Fishery Laboratory in Durres, during the period January 2008 - December 2009. At this time, 863 fish were analysed. For each individual was kept records for weight and height then, otoliths were removed, and finally watched in stereomicroscope (40 X annual assessment circles around the otoliths opaque core. Age of fish is equal to the number of annual rings. The study showed that the average age was 2.22 year, and 70% were 2+ and 3+ years. The average length was 13.98 cm. About 58% of anchovy fish were with length 12.5 - 15 cm. This study will help determine the population dynamics of anchovy fish and more accurate predictions for the amount of fish to hunt in defined time periods.

  14. Continued studies of the gastrointestinal absorption of plutonium by rodents: relationships to feeding regimen and age of animals

    International Nuclear Information System (INIS)

    In mice that are consuming food ad libitum the gastrointestinal absorption of plutonium (and its subsequent retention in liver and skeleton) has been shown to be a factor of about 10 lower than it is in the fasted anaimal. It has been found that the time required to achieve the fasted state is less than two hours for mice that are at the end of their diurnal, inactive phase and between 4 and 8 hours for mice that are 4 hours into their active phase. The absorption of plutonium appears to depend on the nature of materials in the G.I. tract, i.e., properties of the food consumed, rather than amounts present. The fractional absorption of plutonium from the G.I. tract by the rat decreases with age in the unweaned animal, from 7 x 10-3 on day 1 to 3 x 10-3 on day 19 (the latter value being the same as that for the fasted adult) and with weaning to 1 x 10-4 on day 29

  15. Reproductive biology and age determination of Garra rufa Heckel, 1843 (Actinopterygii: Cyprinidae) in central Iran

    OpenAIRE

    ABEDI, Masoud; SHIVA, Amir Houshang; Mohammadi, Hamid; MALEKPOUR, Rokhsareh

    2011-01-01

    Some aspects of the reproductive biology of Garra rufa Heckel, 1843, a native cyprinid fish species from the Armand stream in Chaharmahal-o-Bakhtiari province, central Iran, were investigated by regular monthly collections throughout 1 year. A significant relationship between length and weight and the isometric growth pattern were observed in this fish. There were no significant differences in the total number of male and female specimens. The population of this cyprinid fish had a narrow age...

  16. Studies on the biology of Gymnarchus niloticus in Lake Chad: Age determination and growth; meristic and morphometric characters

    OpenAIRE

    Sagua, V.O.

    1985-01-01

    The meristic and morphometric characteristics of Gymnarchus niloticus are described and linear equations relating various parts of the body to the head length or total length are given. The age of G. niloticus in Lake Chad (Nigeria) was determined from growth marks on the opercular bones. The mean lengths for age, and mean weights for age obtained for the first five years of life are given. The assymptotic length and the von Betarlanffy growth parameters for the males and females combined are...

  17. A New Predictor AMH (anti-müllerian hormone to Determining Ovarian Reserve and Menoposual Aging in the Women

    Directory of Open Access Journals (Sweden)

    Levent Sarýyýldýz

    2013-05-01

    Full Text Available       Anti-mullerian hormone (AMH, also termed Mullerian inhibiting substance (MIS, is produced in ovary by granulose cells and known as a member of the TGF- β superfamily. The researchers imply that AMH is associated with the various growth factors in development and growth of ovarian follicles, furthermore  is exhibited the features of other TGF-β family members. AMH has a critical importance in reproductive age of women. Certain standardization has not yet been developed in determing the ovarian reserve. Recent findings reveal the importance of AMH in determining ovary function and, highlight the importance of AMH than FSH.

  18. Determination of aluminum by four analytical methods

    International Nuclear Information System (INIS)

    Four procedures have been developed for determining the aluminum concentration in basic matrices. Atomic Absorption Spectroscopy (AAS) was the routine method of analysis. Citrate was required to complex the aluminum and eliminate matrix effects. AAS was the least accurate of the four methods studied and was adversely affected by high aluminum concentrations. The Fluoride Electrode Method was the most accurate and precise of the four methods. A Gran's Plot determination was used to determine the end point and average standard recovery was 100% +- 2%. The Thermometric Titration Method was the fastest method for determining aluminum and could also determine hydroxide concentration at the same time. Standard recoveries were 100% +- 5%. The pH Electrode Method also measures aluminum and hydroxide content simultaneously, but is less accurate and more time consuming that the thermal titration. Samples were analyzed using all four methods and results were compared to determine the strengths and weaknesses of each. On the basis of these comparisons, conclusions were drawn concerning the application of each method to our laboratory needs

  19. Older age and dietary folate are determinants of genomic and p16-specific DNA methylation in mouse colon

    Science.gov (United States)

    Elder age and inadequate folate intake are strongly implicated as important risk factors for colon cancer, and each is associated with altered DNA methylation. This study was designed to determine the effect of aging and dietary folate on select features of DNA methylation in the colon that are rele...

  20. ANALYSIS OF AGED IN-HOME CARPETING TO DETERMINE THE DISTRIBUTION OF PESTICIDE RESIDUES BETWEEN DUST, CARPET, AND PAD COMPARTMENTS

    Science.gov (United States)

    This report presents results of a study to determine the distribution of pesticides, polycyclic aromatic hydrocarbons (PAHs) and polychlorinated biphenyls (PCBs) between dust and carpet components in aged carpeting. Carpeting in eight homes in the Research Triangle Area, which...