WorldWideScience

Sample records for afgraensning behandling prognose

  1. Akut dissemineret encefalomyelitis. Afgraensning, behandling, prognose og evidens

    DEFF Research Database (Denmark)

    Christensen, Pia Sønderby; Østergaard, John R

    2008-01-01

    and prognosis for children with ADEM and to evaluate the level of evidence in treatment. MATERIALS AND METHODS: Medical records were found by searching for diagnoses and reviewed retrospectively. The level of evidence in treatment was evaluated by searching PubMed, EMBASE and The Cochrane Library. RESULTS: 11...

  2. Diagnose, behandling og prognose ved fibromyalgi

    DEFF Research Database (Denmark)

    Danneskiold-Samsøe, Bente; Bartels, Else Marie; Amris, Kirstine

    2010-01-01

    It is important to recognize the diagnosis of fibromyalgia (FM) to adequately advise patients with this chronic pain disease. FM coexists with other rheumatic diseases and may therefore serve as a confounder in connection with estimation of disease activity. The aetiology and pathogenesis of FM...

  3. Kognitive forstyrrelser ved depression - betydning for behandling og prognose

    DEFF Research Database (Denmark)

    Ravnkilde, Barbara; Bruun, Louise Meldgaard; Videbech, Poul

    2007-01-01

    Depression is often accompanied by cognitive disturbances, and by focusing on these deficits practitioners can obtain important information about the status of the disease and the prognosis of the patient. From this perspective, patients may also gain useful insight into their own condition. Medi....... Medical and psychological treatment interventions can be applied on different levels particularly in relation to the cognitive symptoms of depression. Udgivelsesdato: 2007-Apr-16......Depression is often accompanied by cognitive disturbances, and by focusing on these deficits practitioners can obtain important information about the status of the disease and the prognosis of the patient. From this perspective, patients may also gain useful insight into their own condition...

  4. Bedre prognose af cystinose ved behandling med cysteamin og nyretransplantation

    DEFF Research Database (Denmark)

    Oczachowska-Kulik, Anna Ewa; Lund, Allan; Skovby, Flemming

    2011-01-01

    Cystinosis is a rare, autosomal recessive disease with cystine deposits in different tissues. First signs come from kidneys and eyes, but during progression of the disease other organs can also be affected. Previously, patients with cystinosis had a very poor prognosis, but it is now considerably...

  5. Gentaget selvmordsforebyggende behandling

    DEFF Research Database (Denmark)

    Lind, Bertel

    2014-01-01

    forbedringer i deres behandling, der kunne oplyse os om effekten af behandlingen på patienterne og på at reducere deres på selvmordsforsøgs rate. Metoder Den metodiske tilgang er mixed design ( Creswell 2009) med både kvantitativ og kvalitativ metode i dataindsamlingen og i analysen. Den overliggende metodiske...

  6. Mentaliseringsbaseret behandling og musikterapi

    DEFF Research Database (Denmark)

    Hannibal, Niels

    2013-01-01

    Denne artikel behandler spørgsmålet, om mentaliseringsbaseret terapi er en metode der medfører et skift i terapeutisk forholdemåde for analytisk orienterede musikterapeuter i arbejde med patienter med personlighedsforstyrrelse. Artiklen skal ses om en del af den teoretiske integrationer af MBT i...

  7. Prognose: SF den store vinder af kommunalvalget

    DEFF Research Database (Denmark)

    Thomsen, Søren Risbjerg

    2009-01-01

    KV-09: SF stormer ifølge Altinget.dks prognose ind i byråd og ikke mindst regionsråd ved valget til november, mens Radikale halveres.......KV-09: SF stormer ifølge Altinget.dks prognose ind i byråd og ikke mindst regionsråd ved valget til november, mens Radikale halveres....

  8. Alternativ behandling og kræft

    DEFF Research Database (Denmark)

    Lunde, Anita; Johannessen, Helle

    2010-01-01

    Baggrund: Interessen for komplementær og alternativ behandling (KAB) er stadig stigende, og der kan dokumenteres et større forbrug af KAB blandt kræftpatienter. Patienter anvender primært KAB som supplement til deres konventionelle behandling, og mange så gerne KAB som en integreret praksis. Fler...

  9. Teknologiers mellemkomst i ambulant behandling og egenomsorg

    DEFF Research Database (Denmark)

    Ballegaard, Stinne Aaløkke; Aarhus, Rikke

    2009-01-01

    Vigtige tendenser i den danske sundhedssektor i disse år er centralisering af behandling og øget egenomsorg. Teknologi ses ofte som en del af denne udvikling, omend der eksisterer både dystopiske og utopiske forestillinger om, hvorvidt teknologi fremmedgør eller støtter patienten. I denne artikel...

  10. Eksperimentel bakteriofagterapi til behandling af kronisk Pseudomonas aeruginosaotitis hos hund

    DEFF Research Database (Denmark)

    Moodley, Arshnee; Mølgaard, Jesper

    2016-01-01

    Vi beskriver en case med anvendelsen af bakteriofager til behandling af kronisk otitis forårsaget af multiresistente Pseudomonas aeruginosa som en sidste behandlingsmulighed før aflivning. Trods gentagne behandlinger, både topikalt og systemisk, med op til seks forskellige antibiotika over en...

  11. Sidste prognose før valget: SF den store vinder

    DEFF Research Database (Denmark)

    Thomsen, Søren Risbjerg

    2009-01-01

    KV09: I sin sidste prognose til Altinget.dk før kommunalvalget tirsdag holder professor Søren Risbjerg Thomsen fast ved SF som den store vinder.......KV09: I sin sidste prognose til Altinget.dk før kommunalvalget tirsdag holder professor Søren Risbjerg Thomsen fast ved SF som den store vinder....

  12. Encephalic hemodynamic phases in subarachnoid hemorrhage: how to improve the protective effect in patient prognoses

    Directory of Open Access Journals (Sweden)

    Marcelo de Lima Oliveira

    2015-01-01

    Full Text Available Subarachnoid hemorrhage is frequently associated with poor prognoses. Three different hemodynamic phases were identified during subarachnoid hemorrhage: oligemia, hyperemia, and vasospasm. Each phase is associated with brain metabolic changes. In this review, we correlated the hemodynamic phases with brain metabolism and potential treatment options in the hopes of improving patient prognoses.

  13. Encephalic hemodynamic phases in subarachnoid hemorrhage:how to improve the protective effect in patient prognoses

    Institute of Scientific and Technical Information of China (English)

    Marcelo de Lima Oliveira; Daniel Silva de Azevedo; Milena Krajnyk de Azevedo; Ricardo de Carvalho Nogueira; Manoel Jacobsen Teixeira; Edson Bor-Seng-Shu

    2015-01-01

    Subarachnoid hemorrhage is frequently associated with poor prognoses. Three different hemo-dynamic phases were identified during subarachnoid hemorrhage: oligemia, hyperemia, and vasospasm. Each phase is associated with brain metabolic changes. In this review, we correlated the hemodynamic phases with brain metabolism and potential treatment options in the hopes of improving patient prognoses.

  14. EVALUATION OF BROWN COAL SPONTANEOUS COMBUSTION AND SOURCES GENESIS PROGNOSES

    Directory of Open Access Journals (Sweden)

    Vlastimil MONI

    2014-10-01

    Full Text Available This article presents summarizing information about the solution of partial part of research problem of prognoses of deposited brown coal spontaneous combustion sources genesis as a part of project TA01020351 – program ALFA. We will gradually describe the results of long term measurements carried out on selected brown coal heaps realized from 2011 to 2013. The attention is devoted to characterization of key parameters. These parameters influence the genesis of combustion. The second problem is the comparison of results of thermal imaging with laboratory results of gas and coal samples sampled in situ, with the influence of atmospheric conditions (insolation, aeration, rainfall, atmospheric pressure changes etc., with influence of coal mass degradation, physical and chemical factors and another failure factors to brown coal spontaneous combustion processes.

  15. Behandling af digital dermatitis på KFC

    DEFF Research Database (Denmark)

    Krogh, Kenneth; Thomsen, Peter

    2008-01-01

    På Kvægbrugets Forsøgscenter blev de rutinemæssige klovbade i maj 2007 erstattet med månedlige tjek af klove i beskærerboks og behandling af klovlidelser, herunder især Digital Dermatitis. Behandlingseffekten har været høj med 90 % helbredte efter en måned. Udgivelsesdato: april 2008......På Kvægbrugets Forsøgscenter blev de rutinemæssige klovbade i maj 2007 erstattet med månedlige tjek af klove i beskærerboks og behandling af klovlidelser, herunder især Digital Dermatitis. Behandlingseffekten har været høj med 90 % helbredte efter en måned. Udgivelsesdato: april 2008...

  16. Er danske sygeplejersker "klædt på" til mødet med patienter, som anvender alternativ behandling

    DEFF Research Database (Denmark)

    Lunde, Anita

    alternativ behandling forekommer af og til, dialogen indgår dog sjældent som et fast punkt i planlagte samtaler, ligesom langt de fleste sygeplejersker aldrig giver konkrete anbefalinger om alternativ behandling. Sygeplejersker anser alternativ behandling som et meget bredt felt, som også afspejler sig i...

  17. Relationship between Radiological Stages and Prognoses of Pneumocystis Pneumonia in Non-AIDS Immunocompromised Patients

    Directory of Open Access Journals (Sweden)

    Xiang-Dong Mu

    2016-01-01

    Conclusions: Based on the radiological manifestations, the course of PCP in non-AIDS immunocompromised patients can be divided into three stages: early stage, mid stage, and late stage. The prognoses of patients treated at early stage are good, and those at late stage are poor. Furthermore, the CFR of patients with barotrauma is high.

  18. Assessing the prognoses on Health care in the information society 2013--thirteen years after.

    Science.gov (United States)

    Knaup, Petra; Ammenwerth, Elske; Dujat, Carl; Grant, Andrew; Hasman, Arie; Hein, Andreas; Hochlehnert, Achim; Kulikowski, Casimir; Mantas, John; Maojo, Victor; Marschollek, Michael; Moura, Lincoln; Plischke, Maik; Röhrig, Rainer; Stausberg, Jürgen; Takabayashi, Katsuhiko; Uckert, Frank; Winter, Alfred; Wolf, Klaus-Hendrik; Haux, Reinhold

    2014-07-01

    Health care and information technology in health care is advancing at tremendous speed. We analysed whether the prognoses by Haux et al. - first presented in 2000 and published in 2002 - have been fulfilled in 2013 and which might be the reasons for match or mismatch. Twenty international experts in biomedical and health informatics met in May 2013 in a workshop to discuss match or mismatch of each of the 71 prognoses. After this meeting a web-based survey among workshop participants took place. Thirty-three prognoses were assessed matching; they reflect e.g. that there is good progress in storing patient data electronically in health care institutions. Twenty-three prognoses were assessed mismatching; they reflect e.g. that telemedicine and home monitoring as well as electronic exchange of patient data between institutions is not established as widespread as expected. Fifteen prognoses were assessed neither matching nor mismatching. ICT tools have considerably influenced health care in the last decade, but in many cases not as far as it was expected by Haux et al. in 2002. In most cases this is not a matter of the availability of technical solutions but of organizational and ethical issues. We need innovative and modern information system architectures which support multiple use of data for patient care as well as for research and reporting and which are able to integrate data from home monitoring into a patient centered health record. Since innovative technology is available the efficient and wide-spread use in health care has to be enabled by systematic information management.

  19. Orale senfølger af behandling for hoved-halscancer

    DEFF Research Database (Denmark)

    Assaad, Hala; Dynesen, Anja Weirsøe; Thisted, Lise Bjerrum;

    2014-01-01

    Forebyggelse af orale senfølger af behandling for hoved-hals-cancer er vigtig for orale funktioner og livskvalitet Patienter, der er strålebehandlet for hovedhals-cancer, oplever betydelige senfølger i mundhulen; herunder xerostomi og hyposalivation, oral candidose, ubehag og smerte fra...... orale senfølger....

  20. Antitrombotisk behandling ved iskæmisk apopleksi og transitorisk cerebral iskæmi

    DEFF Research Database (Denmark)

    Overgaard, Karsten; Poulsen, Tina Svenstrup; Husted, Steen

    2007-01-01

    Nærværende statusartikel omhandler antitrombotisk behandling ved transitorisk cerebral iskæmi (TCI) og iskæmisk apopleksi, dog omtales trombolyse ikke. Behandlingen bør individualiseres efter evidensbaserede principper som anbefalet i nationale og internationale kliniske retningslinjer. Ofte er der...

  1. Ribosomal protein S27-like in colorectal cancer: a candidate for predicting prognoses.

    Directory of Open Access Journals (Sweden)

    Chi-Jung Huang

    Full Text Available BACKGROUND: The development and progression of colorectal cancer (CRC involve a complex process of multiple genetic changes. Tumor suppressor p53 is capable of determining the fate of CRC cells. However, the role of a p53-inducible modulator, ribosomal protein S27-like (RPS27L, in CRC is unknown. METHODS: Here, the differential expression of RPS27L was examined in the feces and colonic tissues of CRC patients, to explore its possible correlation with patient survival and to investigate the cellular mechanisms underlying their clinical outcomes. Eighty intermediate-stage CRC patients (42 at stage II and 38 at stage III were divided into two groups according to their fecal RPS27L mRNA levels. The survival probabilities of the groups were estimated using the Kaplan-Meier method. The RPS27L protein in the colonic tissues of stage III patients with different prognoses was further examined immunohistochemically. RPS27L expression in LoVo cells was manipulated to examine the possible cellular responses in vitro. RESULTS: Elevated RPS27L expression, in either feces or tissues, was related to a better prognosis. In vitro, RPS27L-expressing LoVo cells ceased DNA synthesis and apoptotic activity while the expression of their DNA repair molecules was upregulated. CONCLUSIONS: Elevated RPS27L may improve the prognoses of certain CRC patients by enhancing the DNA repair capacity of their colonic cells, and can be determined in feces. By integrating clinical, molecular, and cellular data, our study demonstrates that fecal RPS27L may be a useful index for predicting prognoses and guiding personalized therapeutic strategies, especially in patients with intermediate-stage CRC.

  2. Mobile vehicles in the Netherlands. Prognoses to the year 2020. Description and application of the model PROMIN; Mobiele werktuigen in Nederland. Prognoses tot 2020

    Energy Technology Data Exchange (ETDEWEB)

    Bouwman, M.E.

    1996-03-01

    Mobile machinery consists of `special vehicles` as well as `off-road vehicles`. According to the Dutch Central Bureau of Statistics (CBS) special vehicles are converted (pick-up) trucks for a specific function, e.g. ambulances, garbage trucks and concrete mixers. Off-road vehicles do not have licence plates, but are self-propelling, are converted (pick-up) trucks for a specific function, e.g. ambulances, garbage trucks and concrete mixers. A model to calculate energy use of and emissions from mobile machinery is described for the period 1990-2020. In 1990 the calculated energy use of off-road vehicles is 28.6 PJ, amounting to 1.0% of the total energy use in the Netherlands. Agricultural machinery (9 PJ) has the largest share in this use, followed by special vehicles, excavators and fork-lift trucks. Emissions from mobile machinery are calculated for a great diversity of compounds using the model. The most important are CO2, CO, VOC, NOx and aerosols. The two CPB scenarios Global Shift and European Renaissance are used in order to make prognoses of energy use of and emissions from mobile machinery. Three policy options are assumed: no policy, a policy in which the actual emission standards are used, and a policy in which the standards are accentuated further for the year 2020. 70 refs.

  3. Fysisk rehabilitering i forbindelse med behandling af hæmatologiske sygdomme

    DEFF Research Database (Denmark)

    Høgdal, Nina; Bartels, Frederik Reith; Smith, Nicholas Simon;

    2015-01-01

    I denne statusartikel vurderes det, hvorvidt det eksisterende fysioterapeutiske træningstilbud under behandling af maligne sygdomme med højdosis kemoterapi og perifer stamcellestøtte (HD-ASCT) lever op til anbefalingerne i Kræftplan III. Alle seks hospitaler i Danmark, som behandler patienter med...... HDASCT, indgår i undersøgelsen. Resultatet af undersøgelsen peger på, at fysisk aktivitet ikke er højt prioriteret på landets hospitaler. Fysioterapinormeringen er sparsom, så daglig prioritering er nødvendig, og enkelte steder er der under indlæggelse ventetid på opstart af fysioterapi...

  4. Blødningsforstyrrelser hos kvinder. Undersøgelse og behandling i almen praksis

    DEFF Research Database (Denmark)

    Astrup, Karen

    1994-01-01

    Artiklen omfatter resultaterne af en spørgeskemaundersøgelse til 200 praktiserende læger efteråret 1992 om lægernes undersøgelse og behandling af forskellige former for blødningsforstyrrelser hos kvinder i almen praksis. Undersøgelsen blev udført mhp. Karen Astrup's deltagelse i expertpanelet til...... konsensuskonferencen "Blødningsforstyrrelser hos kvinder" febr. 1993. Udgivelsesdato: 1994......Artiklen omfatter resultaterne af en spørgeskemaundersøgelse til 200 praktiserende læger efteråret 1992 om lægernes undersøgelse og behandling af forskellige former for blødningsforstyrrelser hos kvinder i almen praksis. Undersøgelsen blev udført mhp. Karen Astrup's deltagelse i expertpanelet til...

  5. Relationship between Radiological Stages and Prognoses of Pneumocystis Pneumonia in Non-AIDS Immunocompromised Patients

    Institute of Scientific and Technical Information of China (English)

    Xiang-Dong Mu; Peng Jia; Li Gao; Li Su; Cheng Zhang; Ren-Gui Wang; Guang-Fa Wang

    2016-01-01

    Background:Although radiological features ofpneumocystis pneumonia (PCP) in non-Acquired Immune Deficiency Syndrome (AIDS) immunocompromised patients have been reported by other authors,there were no studies on the radiological stages of PCP previously.This study aimed to elucidate the radiological stages and prognoses of PCP in non-AIDS immunocompromised patients.Methods:Retrospective analysis ofradiological manifestations and prognoses of 105 non-AIDS PCP immunocompromised patients from August 2009 to April 2016 was conducted.Chest radiograph was divided into three stages:early stage (normal or nearly normal chest radiograph),mid stage (bilateral pulmonary infiltrates),and late stage (bilateral pulmonary consolidations);chest high-resolution computed tomography (HRCT) was also divided into three stages:early stage (bilateral diffuse ground-glass opacity [GGO]),mid stage (bilateral diffuse GGO and patchy consolidations),and late stage (bilateral diffuse consolidations).Results:The case fatality rate (CFR) of all patients was 34.3% (36/105),all of them took routine chest X-ray (CXR),and 84 underwent chest CT examinations.According to the CXR most near the beginning of anti-PCP therapy,18 cases were at early stage and CFR was 0 (0/18,P < 0.0 1),50 cases were at mid stage and CFR was 28.0% (14/50,P > 0.05),and 37 cases were at late stage and CFR was 59.5% (22/37,P < 0.01).According to the chest HRCT most near the beginning ofanti-PCP therapy,40 cases were at early stage and CFR was 20.0% (8/40,P > 0.05),34 cases were at mid stage and CFR was 47.1% (16/34,P > 0.05),and 10 cases were at late stage and CFR was 80.0% (8/10,P < 0.05);barotrauma,including pneumothorax,pneumomediastinum,and pneumohypoderma,was found in 18 cases and the C FR was 77.8% (14/18,P < 0.01).Conclusions:Based on the radiological manifestations,the course of PCP in non-AIDS immunocompromised patients can be divided into three stages:early stage,mid stage,and late stage

  6. Studies on correlation of positive surgical margin with clinicopathological factors and prognoses in breast conserving surgery

    Energy Technology Data Exchange (ETDEWEB)

    Nishimura, Reiki; Nagao, Kazuharu; Miyayama, Haruhiko [Kumamoto City Hospital (Japan)

    1999-09-01

    Out of 484 cases with breast conserving surgery between April 1989 and March 1999, surgical procedures of 34 cases were changed to total mastectomy due to positive surgical margins. In this study we evaluated a clinical significance of surgical margin in relation to clinicopathological factors and prognoses. Ninety-nine cases (20.5%) had positive margins that were judged when cancer cells existed within 5 mm from margin. In multivariate analysis of factors for surgical margin, EIC-comedo status, ly, located site, proliferative activity, and age were significant and independent factors. Regarding local recurrence, positive margin, age, ER and proliferative activity were significant factors in multivariate analysis, especially in cases not receiving postoperative radiation therapy. Radiation therapy may be beneficial for patients with positive surgical margin. And patients with breast recurrence alone had significantly higher survival rates. Therefore, it is suggested that surgical margin may not reflect survival, although it is a significant factor for local recurrence. (author)

  7. EMDR-behandling  : Barns och ungdomars upplevelser en kvalitetssäkringsstudie 

    OpenAIRE

    Fredin, Ingela

    2005-01-01

    Föreliggande studie är dels ett led i att kvalitetssäkra EMDR (Eye Movement Desensitization and Reprocessing) som behandlingsmetod för barn och ungdomar och dels att utröna om behandlingen bidragit till ett förbättrat mående. EMDR som behandlingsmetod för barn och ungdomar har stöd i kontrollerade studier, men ytterligare forskning behövs. I den här studien deltog åtta barn och ungdomar med varierande diagnoser, vilka fått EMDR-behandling i barn- och ungdomspsykiatrisk öppenvård. Behandlingen...

  8. Forskning i ergoterapeutisk behandling indenfor neurorehabilitering - en stor udfordring og nødvendighed!

    DEFF Research Database (Denmark)

    Schow, Trine

    2011-01-01

    Der sker i disse år meget indenfor både forskning og behandling i neurorehabilitering. Både grundforskning og kliniske studier bidrager til viden om neuroplasticitet og til udvikling og dokumentation af forskellige behandlingsformer og det er vigtigt at det ergoterapeutiske felt følger med. Denne...

  9. Revmatoid artritt i Norge – demografi, sykdomskarakteristika og behandling. En sammenligning med andre europeiske land og USA

    Directory of Open Access Journals (Sweden)

    Glenn Haugeberg

    2012-11-01

    Full Text Available Bakgrunn: Revmatoid artritt (RA er en kronisk inflammatorisk leddsykdom som gir økt sykelighet og dødelighet. Nye biologiske legemidler har de siste 10 årene bedret prognosen betydelig. I 2005 ble QUEST-RA (Quantitative Standard Monitoring of Patients with Rheumatoid Arthritis prosjektet etablert for å sammenligne sykdomsstatus og behandling hos RA-pasienter i forskjellige land. I denne artikkelen presenteres status for RA-pasienter i Norge sammenlignet med andre europeiske land og USA.Materiale og metode: Tilfeldig utvalgte RA-pasienter fulgt opp ved revmatologisk poliklinikk ved Sørlandet sykehus i Kristiansand (n=100 og St. Olavs Hospital i Trondheim (n=100 ble inkludert. I henhold til protokoll ble demografiske, sykdoms- og behandlingsdata registrert.Resultater: Norske RA-pasienter skilte seg lite fra gjennomsnittet i andre land med hensyn til alder, utdannelse og sykdomsvarighet. Sykdomsalvorlighet og sykdomsstatus til norske RA-pasienter er sammenlignbare med pasienter fra land som har lavest sykdomsaktivitet og best helsestatus. I Norge er andelen som behandles med biologiske legemidler ca 30%, og Norge er blant de land med størst andel pasienter som behandles med denne legemiddelgruppen. Fortolkning: RA-pasienter i Norge er blant de i Europa som har lavest sykdomsaktivitet. En årsak antas å være den relativt utbredte bruken av biologiske legemidler i Norge.

  10. KIF2A Overexpression and Its Association with Clinicopathologic Characteristics and Poor Prognoses in Patients with Gastric Cancer

    Science.gov (United States)

    Zhang, Shu; Huang, Fang; Wang, Yan; Song, Qinjie; Yang, Xiaobing

    2016-01-01

    Kinesin family protein 2A (KIF2A), an M-type nonmotile microtubule depolymerase, has attracted attention for its role in carcinogenesis and poor prognoses in various human cancers. In this study, we aimed to evaluate the expression of KIF2A and its robustness and potential to predict clinical outcomes in gastric cancer (GC) patients. The messenger RNA (mRNA) expression of KIF2A was determined in 24 pairs of cancerous and adjacent nontumor tissues by real-time polymerase chain reaction. Immunohistochemistry of KIF2A was performed on a tissue microarray composed of 461 GC and 65 matched adjacent nontumor tissues removed during surgeries and 18 chronic gastritis, 15 intestinal metaplasia, and 37 low-grade and 62 high-grade intraepithelial neoplasias acquired through gastric endoscopic biopsies. Univariate and multivariate Cox regression models were used to perform survival analyses. The high KIF2A expression was significantly correlated to histological type, TNM stage, and lymph node metastasis. A negative correlation was found between KIF2A expression and the 5-year survival rate of GC patients. In addition, multivariate analysis indicated that KIF2A is an independent prognostic factor in GC. This study demonstrated the high KIF2A expression might serve as an independent marker for poor prognoses in GC patients.

  11. ELBE - Validation and improvement of load prognoses - Phase 1; ELBE - Validierung und Verbesserung von Lastprognosen (Projektphase 1) - Zwischenbericht

    Energy Technology Data Exchange (ETDEWEB)

    Kronig, P.; Hoeckel, M.

    2008-07-01

    This comprehensive interim report for the Swiss Federal Office of Energy (SFOE) reviews work done at the Bernese University of Applied Sciences concerning various methods for the making of prognoses for grid loading in a liberalised electricity market with increasing supply of power from renewable resources. The liberalised Swiss electricity market is reviewed and production planning instruments are examined, as are the factors that influence such planning. Examples of load profiles are presented and discussed, as are the social, technical and meteorological factors that influence demand. The accuracy of various prognosis methods is reviewed. Simple methods using Excel spread-sheets and MatLab are compared and discussed. Commercially available systems are also briefly examined and work to be done in a second phase of the project is reviewed.

  12. De essentie van de daling in het aantal verkeersdoden : ontwikkelingen in 2004 en 2005, en nieuwe prognoses voor 2010 en 2020.

    NARCIS (Netherlands)

    Stipdonk, H.L. Aarts, L.T. Schoon, C.C. & Wesemann, P.

    2006-01-01

    The essence of the decrease in the number of road deaths; Developments in 2004 and 2005, and new prognoses for 2010 and 2020. During the last 15 to 20 years there was a 2.5% annual decrease in the number of road deaths. This decrease is attributed to all kinds of important, gradual improvements of r

  13. GIM-behandling af en traumatiseret flygtning med PTSD – med fokus på traumebearbejdning

    Directory of Open Access Journals (Sweden)

    Torben Moe

    2016-12-01

    Full Text Available Artiklen omhandler en case med fokus på direkte traumebehandling i traumefokuseret Guided Imagery and Music (GIM. Patienten deltog i et mixed methods feasibility-pilotprojekt vedrørende behandling af traumatiserede flygtninge, som er beskrevet i artiklen Feasibility of trauma-focused Guided Imagery and Music with adult refugees diagnosed with PTSD – a pilot study. Patienten modtog 16 sessioner over en periode på ca. 6 måneder. I artiklen gives eksempler på traumefokuserede interventioner og eksempler på patientens kommentarer, oplevelser, refleksioner og udbytte af behandlingen. Behandlingstilgangen i konteksten med traumatiserede flygtninge er en ny variation inden for spektret af GIM-terapi, og beskrivelsen af behandlingsforløbet understøttes af teoretisk forståelse af processen. Resultater for pilotstudiet viser, at patienten fik signifikant udbytte af terapien. Dette bliver understøttet af patientens egne udtalelser i evalueringen af forløbet samt ud fra data fra de spørgeskemaer, der blev anvendt i undersøgelsen. Patienten har efter GIM-forløbet en score på Harwards Trauma Questionaire (HTQ, som ligger under cut-off for diagnosen PTSD og scorer markant højere på WHO-5 livsstil-skemaet.

  14. Quick scan prognosis of the CO2 emission of horticulture; Quick scan prognose CO2-emissie glastuinbouw

    Energy Technology Data Exchange (ETDEWEB)

    Van der Velden, N.J.A.

    2010-06-15

    In close collaboration with the government, Dutch greenhouse horticulture is developing its own settlement system for CO2 emissions, the so-called CO2 sector system. Such a system should have a total emission space for cultivation (excluding electricity sales). An agreement is being established between the sector and the Dutch government covering the total CO2 emission for the period 2013-2020 (including electricity sales), supplementing the Covenant on Clean and Efficient Agricultural Sectors. This quick scan offers a prognosis of the future CO2 emission of greenhouse horticulture [Dutch] De glastuinbouw ontwikkelt in nauwe samenwerking met de overheid een eigen vereveningssysteem voor CO2-emissie, het zogeheten CO2-sectorsysteem. Bij een dergelijk systeem behoort een totale emissieruimte voor de teelt (exclusief verkoop elektriciteit). Voor de periode 2013-2020 is een afspraak tussen sector en rijksoverheid in de maak over de totale CO2-emissie (inclusief verkoop elektriciteit), in aanvulling op het Convenant Schone en Zuinige Agrosectoren. In deze quick scan wordt een prognose gemaakt van de toekomstige CO2-emissie door de glastuinbouw.

  15. Krankheitsverläufe bei chronischen Erkrankungen : welche Methode der Veränderungsmessung eignet sich zu ihrer Beschreibung und Prognose?

    OpenAIRE

    Bleßmann, Antje

    2004-01-01

    Hintergrund der Studie ist, dass retrospektive Methoden der Veränderungsmessung (VM) nicht in jedem Fall zu Ergebnissen führen, die mit der herkömmlichen Methode (indirekten Methode) übereinstimmen. In welcher Weise sich verschiedene Methoden der VM mit der Erhebung von Parametern der subjektiven Gesundheit zur Dokumentation und Evaluation des Therapieverlaufes und zur Prognose des weiteren Krankheitsverlaufes eignen, ist bisher in Deutschland im Bereich der Rehabilitation nicht untersucht wo...

  16. "Som natt och dag" : Kvinnors upplevelser av att leva med IBS och behandling med låg FODMAP-kost

    OpenAIRE

    Börjesson, Louise; Lindberg, Emelie

    2014-01-01

    Introduktion: Irritable Bowel Syndrome, IBS, är den vanligaste funktionella mag-tarmsjukdomen i västvärlden med en prevalens på cirka 15-20 % i befolkningen. IBS är generellt sett dubbelt så vanligt förekommande hos kvinnor som hos män och majoriteten som drabbas är kvinnor under 40 år. Behandling med låg FODMAP-kost är den mest effektiva kostbehandlingen vid IBS. Det finns få kvalitativa studier om IBS och behandling med låg FODMAP-kost och det behövs en ökad förståelse av hur det är att lev...

  17. Prognose des neurologischen Outcomes nach Herz-Kreislaufstillstand: Macht Temperaturmanagement einen Unterschied? // Prognostication of Neurological Outcome after Cardiac Arrest: Does Hypothermia makes a Difference?

    Directory of Open Access Journals (Sweden)

    Storm C

    2015-01-01

    Full Text Available Today, most survivors after cardiac arrest will receive a targeted temperature management in the post-resuscitation phase. Early the important question of the neurological prognosis occurs. In addition to the neurological examination (motor response to painful stimuli, brain stem reflexes technical diagnostics are widely used (SEP, EEG, CCT, CMRI. Furthermore, the serum concentration of biomarkers, such as neuron-specific Enolase (NSE in clinical routine and others mainly in the context of research (S-100B, CRP, PCT, micro-RNA are determined. After introduction of targeted temperature management, several studies from different centres have re-evaluated prognostic parameters. Hypothermia likely alters the level of neuron-specific enolase, markedly higher cut-offs apply for patients treated with hypothermia. The prognostic value of median nerve SEP remains largely unchanged. The sedation used during hypothermia renders neurological examination unreliable, even a few days after rewarming the lack of a motor response to painful stimuli does not safely exclude good neurological outcome. In addition, the absence of corneal reflexes is a less reliable parameter than the absence of pupillary light response. Recent studies indicate that evaluation of several prognostic parameters and interpretation in synopsis is advisable. In addition, clinical follow-up over a few days and re-evaluation of prognostic parameters may increase safety of a poor outcome prediction. p bKurzfassung: /bAktuell wird die Mehrzahl der Patienten nach erfolgreicher Reanimation mit einem „Targeted Temperature Management“ in der Post-Reanimationsphase behandelt. Bereits zu Beginn der Therapie, aber auch im Verlauf stellt sich die Frage nach der neurologischen Prognose. Neben klinischer Untersuchung (motorische Antwort auf Schmerzreize, Hirnstammreflexe kommen apparative Verfahren (SEP, EEG, CCT, CMRT zum Einsatz. Zusätzlich erfolgt die Bestimmung von Biomarkern, routinem

  18. Behandling af brandskader

    DEFF Research Database (Denmark)

    Lang, Christian Lyngsaa; Partoft, Søren; Astrup, Jakob;

    2015-01-01

    This paper aims to clarify the newly revised guidelines regarding burn injuries as to assist medical personnel dealing with burns. The Department of Burns at Rigshospitalet is the main burn centre in Denmark, and thus creates the National Guidelines of burns treatment. The new guidelines have...

  19. Korrekt behandling af forfrysninger

    DEFF Research Database (Denmark)

    El-Charnoubi, Waseem Ghulam; Bonde, Christian; Alsbjørn, Bjarne F

    2011-01-01

    Frostbite is rare in Denmark and is often associated with psychiatric conditions or drug- and alcohol abuse. It is seen regularly in countries with an arctic climate and tradition for outdoor activities such as skiing and climbing. The past winter in Denmark was long and cold, so we may see this ...... this phenomenon more frequently in the future. We report two cases from the winter 2009/2010 and summarize the pathophysiology and briefly present the treatment strategy....

  20. Behandling af lokaliseret prostatacancer

    DEFF Research Database (Denmark)

    Jakobsen, Henrik; Iversen, Peter; Mikines, Kári J;

    2007-01-01

    The incidence of prostate cancer is increasing sharply in Denmark and an increasing proportion of patients have clinically localised disease at diagnosis. The therapeutic strategy encompasses intended curative therapy: radical prostatectomy with complete removal of the prostate gland and seminal...... vesicles performed as an open procedure or laparoscopically, external beam radiation therapy, or implantation of radioactive seeds into the prostate (brachytherapy). In older patients with good prognostic factors, active surveillance should be considered. The various therapeutic modalities are reviewed...

  1. Behandling af lokaliseret prostatacancer

    DEFF Research Database (Denmark)

    Jakobsen, Henrik; Iversen, Peter; Mikines, Kári J;

    2007-01-01

    The incidence of prostate cancer is increasing sharply in Denmark and an increasing proportion of patients have clinically localised disease at diagnosis. The therapeutic strategy encompasses intended curative therapy: radical prostatectomy with complete removal of the prostate gland and seminal...... vesicles performed as an open procedure or laparoscopically, external beam radiation therapy, or implantation of radioactive seeds into the prostate (brachytherapy). In older patients with good prognostic factors, active surveillance should be considered. The various therapeutic modalities are reviewed....

  2. Behandling af infantile spasmer

    DEFF Research Database (Denmark)

    Hansen, Lars Kjaersgård; Rasmussen, Niels Henrik

    2006-01-01

    Infantile spasms (IS) are characterised by neurodevelopmental regression, a unique type of seizures and a hypsarrhythmic EEG pattern. Studies recommend the medical treatment of IS as a positive short-term outcome with respect to the spasms and in the resolution of the hypsarrhythmia. However, the...

  3. Korrekt behandling af forfrysninger

    DEFF Research Database (Denmark)

    El-Charnoubi, Waseem Ghulam; Bonde, Christian; Alsbjørn, Bjarne F

    2011-01-01

    Frostbite is rare in Denmark and is often associated with psychiatric conditions or drug- and alcohol abuse. It is seen regularly in countries with an arctic climate and tradition for outdoor activities such as skiing and climbing. The past winter in Denmark was long and cold, so we may see...

  4. Behandling af Dupuytrens kontraktur

    DEFF Research Database (Denmark)

    Raundrup Kornø, Maj; Søe, Niels Henrik; Dahlin, Lars B

    2015-01-01

    Dupuytren’s disease treatment Dupuytren’s disease is a hereditary fibroproliferative disease commonly affecting the palmar fascia of the hand, which results in progressive and irreversibly fixed flexion contractures of the hand. It may occur in the sole of the foot or in the penis. Gen­erally, tr......Dupuytren’s disease treatment Dupuytren’s disease is a hereditary fibroproliferative disease commonly affecting the palmar fascia of the hand, which results in progressive and irreversibly fixed flexion contractures of the hand. It may occur in the sole of the foot or in the penis. Gen...

  5. Samfundserhvervet pneumoni--behandling

    DEFF Research Database (Denmark)

    Andersen, Ljubica; Brock, Birgitte; Jakobsen, Preben

    2008-01-01

    Penicillin is the drug of choice for treatment of community-acquired pneumonia (CAP) in Denmark. The primary determinant for therapeutic activity of penicillin is ''penicillin time'' (T>MIC), i.e. time with penicillin concentration above minimum inhibitory concentration. Eradication of S. pneumon......Penicillin is the drug of choice for treatment of community-acquired pneumonia (CAP) in Denmark. The primary determinant for therapeutic activity of penicillin is ''penicillin time'' (T>MIC), i.e. time with penicillin concentration above minimum inhibitory concentration. Eradication of S....... pneumoniae requires T>MIC above 40-50%. The second determinant for therapeutic activity is the ratio between maximum penicillin concentration in serum and MIC (Cmax/MIC). Considering penicillin pharmacokinetics, intravenous penicillin 2 million units four times a day is recommended as empirical treatment...

  6. Behandlingsresistent depression kan behandles

    DEFF Research Database (Denmark)

    Vinberg, Maj; Levinsen, Mette Frandsen; Kessing, Lars Vedel

    2011-01-01

    Depression is considered resistant when two treatment attempts with antidepressants from different classes fail to produce significant clinical improvement. In cases of treatment-resistant depression, it is recommended to reevaluate the diagnosis, clarify comorbidity, substance abuse and lack...... of compliance. Regarding treatment, evidence is sparse, but switching to a different antidepressant, and combination or augmentation with another agent, admission and treatment with ECT are the options. The choice of treatment must be based on the characteristics of the depression, the severity of treatment...

  7. Analysis of prognoses in patients with recurrent multiple glioblastomas%复发性多发胶质母细胞瘤的预后分析

    Institute of Scientific and Technical Information of China (English)

    谢宝树; 张林; 王宇; 贾锋; 殷玉华

    2016-01-01

    Objective To explore the factors related to the prognoses in patients with recurrent multiple glioblastomas. Methods Of 106 patients with recurrent multiple glioblastomas, who underwent surgical resection of the tumors from January, 2005 to December, 2012 in our hospital, and were followed up, 78 suffered from solitary lesion and 28 from multiple lesions. Each patient with multiple tumors was matched with a patient with a solitary glioblastoma on the basis of age, gender, tumorous location, extent of resection, postoperative radiotherapy or chemiotherapy and Karnofsky Performance Scale (KPS) score and then case-control study was performed. The patients’survival time was analyzed by Kaplan-Meier cure and log-rank tests. Results Long-rank test showed that median overall survival time (8.5 months) was significant longer in the patients with solitary glioblastoma than that (4.5 months) in the patients with multiple glioblastomas (P<0.05). The median overall survival time (7.9 months) was significantly longer in the patients with multiple glioblastomas which were totally resected than that (3.6 months) in the patients with multiple glioblastomas which were partially resected (P<0.05). Conclusions It is suggested the prognosis in the patient with multiple glioblastomas is significantly worse than that in patient with solitary glioblastoma. And the more tumor is resected, the better the prognosis will be in the patients with multiple glioblastomas, in who the tumor should be resected totally as possible on the basis of protecting important cerebral function.%目的:探讨复发性多发胶质母细胞瘤(GBM)预后的影响因素。方法2005年1月至2012年12月手术切除并获得完整随访的复发性GBM 106例,其中单发78例,多发28例(多发组);根据患者年龄、性别、肿瘤部位、手术切除程度、术后是否放化疗、术前KPS评分从单发GBM中选取与多发GBM相匹配的病例28例作为对照(单发组);多发

  8. Stress og profylakse samt behandling

    DEFF Research Database (Denmark)

    Netterstrøm, Bo

    2012-01-01

    Prevention of stress should address the stressors and factors which modify the effect of these. At the community level legislation and agreements on the labour market are important tools. At the enterprise level policies to reduce stress and monitoring the psychosocial work environment has...... the first priority in prevention. Treatment of stress is often a long-term process involving diagnostic assessment, psycho-education and counselling. The Danish National Board of Health has published recommendations to both general practitioners and the public in this area....

  9. Diagnostik og behandling af trigeminusneuralgi

    DEFF Research Database (Denmark)

    Maarbjerg, Stine; Heinskou, Tone Bruvik; Wolfram, Frauke

    2016-01-01

    Trigeminal neuralgia (TN) is characterized by unilateral evoked short-lasting intense pain paroxysms in the face. A concomitant persistent background pain is frequently present. Neurovascular contact causing displacement or atrophy of the trigeminal nerve is important to TN aetiology. TN can also...

  10. Behandling af astma hos gravide

    DEFF Research Database (Denmark)

    Akram, Iram; Ulrik, Charlotte Suppli; Johnsen, Claus Rikard

    2016-01-01

    Asthma is one of the most frequent chronic diseases which complicate pregnancy. Well-controlled asthma during pregnancy reduces the risk of for exacerbations and, consequently, the risk of adverse pregnancy outcome. Pharmacological therapy for pregnant women with asthma is a challenge, not least...... due to suboptimal adherence with controller therapy and pregnant women's concerns about harmful effects of medication on the fetus. This review provides an update on the safety of asthma medication during pregnancy, based on recent clinical studies and international guidelines....

  11. Behandling af gener efter whiplash

    DEFF Research Database (Denmark)

    Rittig-Rasmussen, Bjarne; Kongsted, Alice; Carstensen, Tina Birgitte;

    2010-01-01

    Treatment of whiplash-associated disorders starts with a thorough clinical examination, which may be repeated after 1-3 weeks. For optimal results it is essential that the patient receives clear information about the condition and that any pain is treated effectively with analgesics. Risk factors...

  12. Onkologisk behandling af meningeal carcinomatose

    DEFF Research Database (Denmark)

    Sulim, S.; Høyer, Morten

    2005-01-01

    Meningeal carcinomatosis (MC) occurs in 5-8% of cancer patients. In the       majority of cases, MC appears in patients with advanced disease. The       increase in incidence is probably caused by improved survival due to       improvements in systemic therapy and an increased awareness of MC among...

  13. Biologisk behandling af spondylitis ankylopoietica

    DEFF Research Database (Denmark)

    Freiesleben, S.; Schou, M.

    2008-01-01

    All of the three well-known TNF alpha inhibitors (infliximab, adalimumab and etanercept) have a rapidly occurring and long-lasting effect in ankylosing spondylitis (AS). The IL-1 antagonist, anakinra, has been investigated in two open label studies with partially conflicting results. Apart from...

  14. Behandling af neuroendokrine gastrointestinale tumorer

    DEFF Research Database (Denmark)

    Hansen, Carsten Palnaes; Langer, Seppo; Frevert, Susanne;

    2010-01-01

    of cure. Palliative therapy includes surgery and intra-arterial embolization of hepatic metastases, chemotherapy, biotherapy with interferon-alpha and radionuclear treatment. Tumour-targeted therapy with tyrosine kinase inhibitors, mammalian target of rapamycin inhibitors or monoclonal antibodies...

  15. Diagnostik og behandling af fenylketonuri

    DEFF Research Database (Denmark)

    Bayat, Allan; Møller, Lisbeth Birk; Lund, Allan Meldgaard

    2015-01-01

    Primary phenylalanine hydroxylase deficiency, also known as phenylketonuria, results in accumulation of phenylalanine in the blood. Early identification and treatment prevents the majority of clinical sequelae to the disease, but psychological and neurodevelopmental problems can occur in some...

  16. Behandling af hydatidose med albendazol

    DEFF Research Database (Denmark)

    Magnussen, P; Gelletlie, R; Bygbjerg, Ib Christian

    1989-01-01

    Eight patients with hydatidosis treated with albendazol in daily doses of 10 mg/kg daily in courses of 28 days (4-6 courses) were analysed. The patients came from Morocco, Spain, Turkey and Yugoslavia. Seven patients had a cyst (or cysts) in the liver and one had also cysts in the kidneys. One...

  17. Kirurgisk behandling af cancer pancreatis

    DEFF Research Database (Denmark)

    Bergenfeldt, Magnus; Hansen, Carsten Palnaes; Mortensen, Michael Bau

    2010-01-01

    Surgery remains the only hope for cure in pancreatic cancer. The most common procedures are reviewed. Postoperative morbidity and mortality below 30% and 5%, respectively, are the standard. The benefit of extended lymph node dissection and portal-mesenteric vein resection is dubious. Selected...... patients with locally advanced cancer may be down-staged with chemo-radiotherapy and eventually resected. Endoscopic stent placement is the preferred method to relieve biliary and/or gastrointestinal obstruction. The outcome is better for patients treated at high-volume centres than at smaller hospitals....

  18. Gastropleural fistel kan behandles torakoskopisk

    DEFF Research Database (Denmark)

    Laugesen, Sofie; Nekrasas, Vytautas; Haahr, Poul Erik

    2014-01-01

    Gastropleural fistula (GPF) is although uncommon a severe and sometimes fatal complication after prior thoracic surgery, trauma or malignancy. Standard therapy has often included major surgery such as laparotomia with gastrectomi. In this case report we present a patient with GPF who underwent...

  19. Udredning og behandling af reflekssynkoper

    DEFF Research Database (Denmark)

    Mehlsen, Jesper; Mehlsen, Anne-Birgitte

    2008-01-01

    Syncope is associated with considerable costs to society as well as to the patient. Syncope may arise on a neurological, cardiac, or neurovascular background. Cardiac and neurological causes are evaluated by standard methods. Neurovascular syncope is diagnosed by tilt table testing and carotid ma...... massage. The treatment of neurological or cardiac syncope aims at the underlying cause, whereas the treatment of neurovascular syncope consists of information and instruction in reasonable precautions. In persisting cases, medical treatment or pacemaker implantation may be necessary....

  20. Behandling af insulinom med alkoholsklerosering

    DEFF Research Database (Denmark)

    Schnack, Christina; Hansen, Carina Ørts; Beck-Nielsen, Henning;

    2012-01-01

    The efficacy and safety of endoscopic ultrasound (EUS)-guided alcohol ablation of an insulinoma in a patient not candidate for surgery is being evaluated. A 89 year-old male patient with insulinoma and serious cardiac disease was treated with EUS-guided alcohol ablation. The only complication...

  1. Pneumocystepneumoni ved behandling med infliximab

    DEFF Research Database (Denmark)

    Josephson, Maria Eklund; Kristensen, Lena Hagelskjaer; Andersen, Vibeke

    2008-01-01

    The treatment of ulcerative colitis has improved since the appearance of Tumor Necrosis Factor (TNF)-alpha inhibitors. However, the use of TNF-alpha inhibitors increases the risk of opportunistic infections. We describe two cases of Pneumocystis jiroveci pneumonia during infliximab therapy...... for active ulcerative colitis. They were successfully treated with sulfametoxazole/trimetroprim. High awareness of P. jiroveci pneumonia in patients who develop pulmonary symptoms with hypoxia during TNF-alpha modulator therapy is recommended....

  2. Diagnose og behandling af binyrebarkkarcinom

    DEFF Research Database (Denmark)

    Abildgaard, Julie; Pappot, Helle; Petersen, Peter Meidahl;

    2013-01-01

    Adrenocortical carcinomas (ACC) are rare tumours responsible for only 0.02% of the total number of malignant diseases. However the ACC are aggressive with a mean fiveyears survival of 20-50% and are often associated with increased production of adrenocortical hormones. The effect of the treatment...... is controversial and often based on small retrospective series or expert opinions. Centralization, international attention and collaboration in the treatment of ACC are mandatory. Randomized clinical trials are needed to determine the best treatment strategy in order to increase survival in patients with ACC....

  3. Kirurgisk behandling af cancer pancreatis

    DEFF Research Database (Denmark)

    Bergenfeldt, Magnus; Hansen, Carsten Palnaes; Mortensen, Michael Bau

    2010-01-01

    Surgery remains the only hope for cure in pancreatic cancer. The most common procedures are reviewed. Postoperative morbidity and mortality below 30% and 5%, respectively, are the standard. The benefit of extended lymph node dissection and portal-mesenteric vein resection is dubious. Selected...

  4. Hypertension--forekomst og behandling

    DEFF Research Database (Denmark)

    Ibsen, Hans; Jørgensen, Torben; Jensen, Gorm B;

    2009-01-01

    Hypertension is the most important modifiable risk factor for cardiovascular disease. However, less than half of all hypertensives have their blood pressure reduced to relevant goals. The prevalence of hypertension in Denmark was found to be between 26% and 40% of the adult population. Just over ...... half were aware of the diagnosis, but less than half were in treatment. Blood pressure control in patients who are undergoing treatment has improved during recent years, but there is still a gap to achievable control rates. Udgivelsesdato: 2009-Jun-8...

  5. Hypertension--forekomst og behandling

    DEFF Research Database (Denmark)

    Ibsen, Hans; Jørgensen, Torben; Jensen, Gorm B;

    2009-01-01

    Hypertension is the most important modifiable risk factor for cardiovascular disease. However, less than half of all hypertensives have their blood pressure reduced to relevant goals. The prevalence of hypertension in Denmark was found to be between 26% and 40% of the adult population. Just over ...... half were aware of the diagnosis, but less than half were in treatment. Blood pressure control in patients who are undergoing treatment has improved during recent years, but there is still a gap to achievable control rates....

  6. Gir tidlig vurdering og behandling hos spesialist i fysikalsk medisin og rehabilitering reduksjon i langtidsfravær hos sykmeldte med muskel- og skjelettsykdommer?

    Directory of Open Access Journals (Sweden)

    Harald Elvsåshagen

    2010-01-01

    Full Text Available Bakgrunn: De fleste langtidssykmeldte med muskel- og skjelettsykdommer blir utredet, behandlet og fulgt opp av fastlege. Ved lengre tids sykmelding henvises mange fra sin fastlege til spesialist i fysikalsk medisin og rehabilitering for å optimalisere behandlingsopplegget.Formålet med denne studien var å undersøke om henvisning direkte fra NAV til spesialist uten å gå veien om fastlege, medførte redusert antall sykmeldingsdager og mindre bruk av andre trygdeytelser som rehabiliteringspenger, yrkesrettet attføring og uførepensjon.Materiale og metode: I samarbeid med 14 NAV-kontor i Vestfold ble 829 sykmeldte i alder 25-50 år med 8-12 ukers sykmelding for muskel- og skjelettsykdommer randomisert til en intervensjonsgruppe (n=409 og en kontrollgruppe (n=420. Eksklusjonskriterier var manglende arbeidsforhold, revmatiske sykdommer, brudd og leddsykdommer. Intervensjonsgruppen ble undersøkt og behandlet av spesialist i fysikalsk medisin og rehabilitering, Spesialsykehuset for rehabilitering, avd. Stavern. Kontrollgruppen fortsatte behandling hos sin fastlege. Noen av disse pasientene ble henvist til samme poliklinikk eller til annen spesialist på initiativ fra sin fastlege. Data for sykmeldingsdager, uførepensjon, rehabiliteringspenger og attføringspenger ble samlet inn fra NAV-kontorene. De samme parametre ble brukt som endepunkter. Etter to år ble endepunktene analysert. Data ble analysert etter "intention to treat"- prinsippet.Resultater: I intervensjonsgruppen var gjennomsnittlig antall sykmeldingsdager 138 dager (SD 86,2 mot 147 dager (SD 88,0 i kontrollgruppen, en forskjell på ni sykmeldingsdager. Forskjellen er ikke statistisk signifikant (p=0,163. Det var heller ikke statistisk signifikant forskjell i forbruket av yrkesrettet attføring og rehabiliteringspenger mellom intervensjonsgruppen og behandlingsgruppen.Konklusjon: Henvisning til spesialist i fysikalsk medisin og rehabilitering direkte fra NAV etter 8-12 ukers sykmelding

  7. Short-and Long-Term Clinical Prognoses of Various Types of Fetal Arrhythmia%不同类型胎儿心律失常的临床近远期预后分析

    Institute of Scientific and Technical Information of China (English)

    常惠婷; 李辉

    2012-01-01

    目的:对胎儿心律失常孕妇进行随访,分析其近远期预后,为临床工作提供参考.方法:回顾性分析2004年4月至2010年12月于中国医科大学附属盛京医院进行胎儿心脏超声检查诊断为胎儿心律失常的541例孕妇的临床资料,并进行追踪随访.结果:①541例胎儿心律失常孕妇中,胎儿期前收缩303例(56.01%);快速胎儿心律失常196例(36.23%),其中窦性心动过速92例,室上性心动过速101例,心房扑动3例;胎儿心动过缓42例(7.76%),其中房室传导阻滞8例,窦性心动过缓34例.②共随访391例,失访150例,随访时间1~5年.其中合并胎儿心脏结构异常18例(3.33%),随访15例,有14例终止妊娠放弃胎儿;未合并胎儿心脏结构异常孕妇中有3例因出现胎儿水肿、心力衰竭终止妊娠;不愿承担风险自愿选择终止妊娠10例,分别为室上性心动过速1例,心房扑动2例,房室传导阻滞4例,严重窦性心动过缓3例.产前给予药物治疗共10例,8例有效,2例无效出现胎儿水肿终止妊娠.③共计364例患者继续妊娠,其中期前收缩的胎儿211例,后随访仅1例转归异常;快速胎儿心律失常中窦性心动过速65例和室上性心动过速67例均无转归异常;胎儿心动过缓21例,仅1例于新生儿期死亡.转归正常的患儿生长发育情况等同于正常同龄儿,预后良好.结论:胎儿心律失常类型多样,预后不同,应根据具体类型决定个体化治疗和临床处理方案.发生胎儿心力衰竭、水肿和合并有心脏畸形时,提示预后不良,需要积极进行临床干预,必要时终止妊娠放弃胎儿.胎儿期前收缩临床上最常见,其和胎儿窦性心动过速、室上性心动过速的预后较好.%Objective: Analysis of the short-term and long-term prognoses of various types of fetal arrhythmia. Methods :541 cases diagnosed of fetal arrhythmia in Shengjing Hospitai from April 2004 to December 2010 were enrolled ,and the short

  8. Effect of thyroid disorders on prognoses of acute myocardial infarction patients%甲状腺功能紊乱对急性心肌梗死预后的影响

    Institute of Scientific and Technical Information of China (English)

    杜冬梅; 任颖; 魏盟; 邵琦; 赵催春

    2011-01-01

    Objective To evaluate the influence of thyroid disorders on the incidence and prognosis of acute myocardial infarction (AMI) patients. Methods A total of 463 AMI patients were included in the present study. The thyroid hormone levels were determined in all patients on the next day of admission. The patients were divided into different groups and the cardiac events were observed during hospitalization. Results Among the 463 patients, 239(51.6 % ) had normal thyroid hormone level, and 168 (36.3 % ) had non-thyroidal illness syndrome.There were 40 (8.6 % ) patients with subclinical hyperthyroidism and 6 ( 1.3 % ) with subclinical hypothyroidism.Hyperthyroidism and hypothyroidism were both found in 5 patients. Compared with the euthyroid group, the incidences of congestive heart failure, origin of shock incidence, and in-hospital death increased in the nonthyroidal illness syndrome group (P< 0. 05, 0. 01 ). Multivariate cox regression displayed that FT3 was an independent factor associated with long-term mortality. A decrease of 1 pmol/L in FT3 was associated with an increased risk of death by 59. 8%. Conclusion Thyroid disorder is frequently seen in patients with acute myocardial infarction. NTIS is significantly correlated with the short-time and long-time prognoses of AMI patients.%目的 探讨急性心肌梗死(AMI)时甲状腺功能紊乱的发生情况及对预后的影响.方法 人选463例AMI患者,入院次日测定甲状腺激素水平.观察住院期间心血管事件发生情况并进行远期随访.结果 AMI患者中甲状腺功能正常(功能正常组)239例(51.6%),非甲状腺性病态综合征(NTIS,NTIS组)168例(36.3%),亚临床甲状腺功能亢进症40例(8.6%),亚临床甲状腺功能减退6例(1.3%),甲状腺功能亢进5例(1.1%),甲状腺功能减退5例(1.1%).NTIS组在住院期间的充血性心力衰竭、心源性休克和死亡的发生率均显著高于功能正常组(P值分别<0.05、0.01).Cox模型分析显示,在校

  9. Particle Reduction Strategies - PAREST. Prognosis of air quality and assessment of limit value exceedances in Germany for the reference years 2010, 2015 and 2020; Strategien zur Verminderung der Feinstaubbelastung - PAREST. Prognose der Luftqualitaet und Abschaetzung von Grenzwertueberschreitungen in Deutschland fuer die Referenzjahre 2010, 2015 und 2020. Teilbericht

    Energy Technology Data Exchange (ETDEWEB)

    Stern, Rainer [Freie Univ. Berlin (Germany). Inst. fuer Meteorologie, Troposphaerische Umweltforschung

    2013-06-15

    With the help of a data assimilation technique (optimal interpolation) a comprehensive forecast of O{sub 3}, PM10 and NO{sub 2} air quality in Germany for the years 2010, 2015 and 2020 was prepared. Based on these results, an assessment was made whether the limits of the European Air Quality Directive (2008/50/EC) can be observed in 2015 and 2020. [German] In diesem Bericht wurde mit Hilfe einer Datenassimilationstechnik (Optimale Interpolation) eine flaechendeckende Prognose der O{sub 3}-, PM10- und NO{sub 2}-Luftqualitaet in Deutschland fuer die Jahre 2010, 2015 und 2020 erstellt. Auf Basis dieser Ergebnisse wurde eine Abschaetzung vorgenommen, ob die Grenzwerte der europaeischen Luftqualitaetsrichtlinie (2008/50/EG) im Jahre 2015 und 2020 eingehalten werden koennen. Weiterhin wurde untersucht, was die in der Luftqualitaetsrichtlinie festgelegten Regelungen fuer die Feinstaeube PM2.5 fuer die PM2.5-Belastung in Deutschland bedeuten und ob das nationale Ziel fuer die Reduktion der PM2.5-Belastung unter den Emissionsbedingungen des Jahres 2020 erreicht werden kann.

  10. Project 'Windbank upper Aare Valley': Classification, diagnosis and prognosis of wind fields in the region of the Swiss nuclear power plant Muehleberg; Projekt 'Windbank oberes Aaretal': Klassifizierung, Diagnose und Prognose von Windfeldern in der Region des Kernkraftwerkes Muehleberg

    Energy Technology Data Exchange (ETDEWEB)

    Graber, W.K.; Tinguely, M

    1999-10-01

    erarbeiten. Ausgehend von den mittleren Windwerten fuer jede Klasse werden anschliessend 3-dimensionale Windfelder auf einem regelmaessigen Gitter im Umfeld von 50x50 km berechnet. Diese Windfelder bilden die Grundlage, um typische Dispersionsszenarien fuer eine hypothetische Quelle zu berechnen. Weiter wird eine Methode zur Bestimmung eines aktuellen Windfeldes aufgrund der Routine-Stationen (ohne PSI-Stationen und SODARs) erarbeitet, die in 96 % aller Faelle das richtige Windfeld diagnostiziert. Damit kann eine Windfelddiagnose im on-line-Betrieb realisiert werden. Zur optimalen Nutzung der Windfeldklassierung als Planungsinstrument fuer Massnahmen bei Reaktorstoerfaellen wird eine Methode dargestellt, die eine Prognose der in den naechsten 24 Stunden zu erwartenden Windfeldklassen erlaubt. Die Methode stuetzt sich auf das operationell eingesetzte 'Schweizer Modell' der Schweizerischen Meteorologischen Anstalt und kann ebenfalls in einen on-line-Betrieb der Windfeldprognose eingebunden werden. Die Qualitaet der Prognose der Windfeldklassen wird mit 79 % abgeschaetzt. (author)

  11. 利用Agilent定制基因芯片筛选相同病理类型、不同预后的早期乳腺癌的分子标记物%Screening molecular markers in early breast cancer of the same pathological types but with different prognoses using Agilent gene chip

    Institute of Scientific and Technical Information of China (English)

    厉周; 金维荣; 彭亮; 韩帅; 黄宗海; 史福军; 蔡寨; 李秀勤; 张普生; 朱卉娟

    2013-01-01

    Objective:To screen molecular markers in early breast cancer and establish gene subtyping-based diagnostic criteria for predicting the prognosis of early breast cancers. Methods Tumor tissue specimens were obtained from 8 patients with early breast cancer for analysis of the differentially expressed genes using Agilent custom 8 × 15 000 chips in combination with the prognostic data of the patients. Another 42 tumor tissue specimens were used to validate the differential genes by real-time fluorescent quantitative PCR. Results Gene microarray analysis identified 132 differentially expressed genes between the patients with favorable and poor prognosis, and 44 of these genes were significantly up-regulated (by over two folds) and 88 down-regulated in patients with poor prognoses. Conclusion The gene expression profiles differ in early breast cancer tissues of the same pathological type but with different clinical stages and prognoses, and CD44, MKI67, NTRK2, Nek2, C16orf60, TOP2A, ANCCA, and RRM2 genes can be used as the prognostic markers for early breast cancer.%目的分析相同病理类型、临床分期(Ⅰ~Ⅱ期)但预后不同的乳腺癌组织的基因表达差异,筛选出有意义的基因组合,寻找与乳腺癌预后相关的基因,探索可以早期预测乳腺癌预后的基因分型诊断标准。方法用Agilent定制人8×15000芯片对筛选出的实验组8例早期乳腺癌患者的组织标本,结合其预后数据,进行差异基因表达分析;采用Real-time PCR技术,在同期收集的验证组42例乳腺癌样本中对差异表达的基因进行验证。结果基因芯片检测分析发现,实验组预后差样本比预后好样本有差异表达基因132个,其中44条基因显著上调,88条基因显著下调(差异均在2倍以上)。结论相同病理类型、临床分期、不同预后的早期乳腺癌组织中基因表达存在显著差异,CD44、MKI67、NTRK2、Nek2、C16orf60、TOP2A、ANCCA、RRM2

  12. Ny behandling af kronisk hepatitis B

    DEFF Research Database (Denmark)

    Andersen, Ellen Sloth; Weis, Nina M

    2008-01-01

    Worldwide, 350 million people are infected with chronic hepatitis B. Over the last few years, it has been possible to treat chronic hepatitis B. Treatment very often consists of nucleos(t)ide analogs and in a few cases of pegylated alpha-interferon. In 2007, a new nucleoside analog, Telbivudine......, was approved to treat chronic hepatitis B. In phase II and ongoing phase III studies, Telbivudine has proven more effective than the nucleoside analog, Lamivudine, which was very often used up until recently. Udgivelsesdato: 2008-Nov-24...

  13. Traditionel og alternativ behandling af sklerosepatienter

    DEFF Research Database (Denmark)

    Stenager, E N; Stenager, Egon; Knudsen, L;

    1989-01-01

    The medicine consumption and the employment of alternative treatment were investigated in a material of 117 patients with disseminated sclerosis (DS) considered to be a representative sample of the patients with DS in the County of Funen. This investigation revealed that the preparations most...... commonly employed to modify the disease among patients with disseminated sclerosis were: spasmolytics, agents to counteract neurogenic bladder symptoms, benzodiazepine and analgesics. The consumption of medicine increased with increasing handicap. Employment of psychopharmaca was commonest in patients...

  14. Herpes zoster: klinik, diagnostik og behandling

    DEFF Research Database (Denmark)

    Kofoed, Kristian; Rønholt, Finn; Gerstoft, Jan

    2011-01-01

    Herpes zoster (HZ) is a painful vesicular rash localized to one dermatome. Post-herpetic neuralgia (PHN) is persistent pain three months after the rash started. In recent years several Cochrane reviews and clinical studies on how to treat HZ and PHN have been published. These studies show...

  15. Ny viden om spasticitet og dens behandling

    DEFF Research Database (Denmark)

    Lorentzen, Jakob; Willerslev-Olsen, Maria; Crone, Clarissa;

    2012-01-01

    Spasticity is a frequently used diagnosis, and anti-spastic medication is used widespread. In this systematic review article we highlight difficulties in diagnosing spasticity correctly and thus limit the value of the diagnosis in ensuring the best possible treatment. We review recent neuroscienc...

  16. Nyrefunktionen under behandling med angiotensinkonverterende enzymhaemmere

    DEFF Research Database (Denmark)

    Rasmussen, K; Heitmann, M; Nielsen, J I;

    1995-01-01

    The use of ACE-inhibitors has increased greatly during the last years. They were first used in treating hypertension, but nowadays cardiac diseases, mainly cardiac failure, are common indications. This means that the drugs are used in the treatment of more elderly patients who often have generali......The use of ACE-inhibitors has increased greatly during the last years. They were first used in treating hypertension, but nowadays cardiac diseases, mainly cardiac failure, are common indications. This means that the drugs are used in the treatment of more elderly patients who often have...... generalised atherosclerosis. This means that the patients must be controlled more often after initiation of treatment, especially concerning kidney function, since treatment with ACE-inhibitors can cause pronounced changes in renal haemodynamics and kidney function. This review focuses on the effects of ACE......-inhibitors on renal haemodynamics and kidney function, which may be positive, with preservation of kidney function in diabetic and other chronic nephropathy, or negative, for example in cases with atherosclerotic stenosis of large or small renal arteries. It is concluded, that in cases of diabetic nephropathy an ACE...

  17. Brystkræft--kirurgisk behandling

    DEFF Research Database (Denmark)

    Christiansen, Peer Michael; Kroman, Niels; Elberg, Jens Jørgen;

    2007-01-01

    This short review of surgical treatment of breast cancer includes a description of indications and contraindications for the common surgical procedures as well as more recently introduced techniques. The latter are mainly operations performed in cooperation between breast and plastic surgeons...

  18. Kirurgisk behandling af aldersrelateret makuladegeneration (AMD)?

    DEFF Research Database (Denmark)

    Kiilgaard, Jens Folke

    2001-01-01

    oftalmologi, aldersrelateret makuladegeneration, transplantation, grise, øjne, kirurgisk udvikling......oftalmologi, aldersrelateret makuladegeneration, transplantation, grise, øjne, kirurgisk udvikling...

  19. Fysisk aktivitet - en behandling af erektil dysfunktion

    DEFF Research Database (Denmark)

    Gerbild, Helle Nygaard

    2016-01-01

    Erectile dysfunction (ED) is typically linked to the risk factors: Physical inactivity, obesity, hypertension, metabolic syndrome, diabetes mellitus or cardiovascular diseases. This thesis results in novel knowledge showing that physiotherapists with guidance on physical activity may contribute...

  20. Skal tavs iskaemi diagnosticeres og behandles?

    DEFF Research Database (Denmark)

    Bech, J; Egstrup, K; Mickley, H;

    1995-01-01

    Silent ischaemia (objective signs of myocardial ischaemia without symptoms) can be diagnosed using a conventional exercise-test or ambulatory Holter monitoring. Silent ischaemia is a frequent phenomenon in patients with ischaemic heart disease, i.e. patients with angina pectoris or previous...

  1. Impotens forarsaget af behandling med methotrexat

    DEFF Research Database (Denmark)

    Penninga, Ida Elisabeth Irene; Larsen, H.K.; Andersen, S.E.

    2008-01-01

    Methotrexate (MTX) is used in the treatment of malignant and non-malignant diseases. This case report describes impotence as a seldom but possible overlooked adverse effect to MTX treatment. A 58 year-old man was treated for erythrodermia with a weekly dose of 7.5 mg MTX. He developed erective...... impotence nine months after initiation of treatment. Two weeks after discontinuation of MTX the impotence subsided, but when MTX treatment was reintroduced, the impotence returned after two months. Only a few other cases of impotence associated with MTX have been described previously Udgivelsesdato: 2008/1/28...

  2. Diagnostik og behandling af øsofagusperforationer

    DEFF Research Database (Denmark)

    Novrup, Hans Gram; Mortensen, Michael Bau; Jungersen, Dorte

    2011-01-01

    The treatment of oesophageal perforations (EP) has primarily been a surgical issue and despite significant advances in surgery and intensive care medicine EP is continuously associated with high morbidity and mortality. Implementation of an effective treatment algorithm which steps away from...... and the establishment of a controlled fistula....

  3. Den kardiovaskulaere risikoprofil og antihypertensiv behandling

    DEFF Research Database (Denmark)

    Zittel, S; Moll, C K E; Hamel, W

    2009-01-01

    Estimation of absolute cardiovascular risk is important for choice of primary as well as secondary cardiovascular prevention. In general, physicians are advised to use SCORE in apparently healthy subjects with optimal or normal blood pressure, the ESH risk stratification chart in patients...... with hypertension and either one or even better a combination of the two instruments in apparently healthy subjects with a high normal blood pressure. Udgivelsesdato: 2009-Jun...

  4. Elektrokemoterapi til behandling af kutane metastaser

    DEFF Research Database (Denmark)

    Falk, Hanne; Matthiessen, Louise Wichmann; Dahlstrøm, Karin;

    2015-01-01

    effect by at least 300-fold. Electrochemotherapy is an efficient, once only treatment for cutaneous metastases with an objective response of 62-99%. Electrochemotherapy can reduce discomfort such as ulceration, oozing, bleeding and pain. Adverse events depend on the size of treatment area, but are very......Cutaneous metastases occur in up to 9% of all patients with cancer and may cause discomfort and stigmatization. Electrochemotherapy is a local treatment using electric pulses to permeabilize cell membranes, enabling chemotherapy, such as bleomycin, to enter the cells and increase the cytotoxic...

  5. Smitteopsporing og profylaktisk behandling af tuberkulose

    DEFF Research Database (Denmark)

    Seersholm, Niels; Wilcke, Torgny

    2011-01-01

    Contact tracing is an integrated part on tuberculosis management and is conducted by the medical officer in collaboration with the local chest clinics. The principle of contact tracing is to begin with the household contacts and expanding to more peripheral contacts depending of the number...

  6. Diagnostik og behandling af akut colonpseudoobstruktion

    DEFF Research Database (Denmark)

    Ertberg, Pia; Vilandt, Jesper; Bødker, Birgit

    2013-01-01

    Acute colonic pseudo-obstruction (ACPO), also known as Ogilvie's syndrome, is a clinical condition with acute dilatation of the colon without a provable mechanical cause. Early recognition and treatment of the condition is important in order to improve the outcome. The diagnosis is based on clini...

  7. Infraktioner i dentin - diagnostik og behandling

    DEFF Research Database (Denmark)

    Pallesen, Ulla

    2011-01-01

    Symptomgivende dentininfraktioner (SDI) kan ofte præsentere tandlægen for et diagnostisk og behandlingsmæssigt dilemma. Patienten kan ikke udpege tanden i tandrækken, ofte end ikke oplyse, om det er i over- eller underkæbe, men har rigtigt ondt en gang imellem, når der tygges i den angivne side...

  8. Biologisk behandling af psoriasis og psoriasisartritis

    DEFF Research Database (Denmark)

    Kragballe, Knud; Deleuran, Bent

    2008-01-01

    Psoriasis is an immune-mediated inflammatory skin disease which may be associated with psoriatic arthritis. Biological therapy is indicated in patients who do not respond to, or are intolerant to, or have contraindication against traditional therapy. TNFalpha antagonists are used for both skin...... and joint disease, while efalizumab, which targets T lymphocytes, is only indicated for the skin disease. Registration of the treated patients in quality databases is an essential instrument in the surveillance of beneficial and adverse events during biological therapy. Udgivelsesdato: 2008-Jun-9...

  9. Behandling af Tourettes syndrom med aripiprazol

    DEFF Research Database (Denmark)

    Stenstrøm, Anne Dorte; Sindø, Ingrid

    2008-01-01

    , due to TS. The initial treatment consisted of pimozide and risperidone, both of which had an unsatisfactorily efficacy on tics and side effects in the form of weight gain and sedation. The patient is now treated with aripiprazole and there is a marked reduction of tics and no side effects...

  10. Kirurgisk behandling af type 2-diabetes

    DEFF Research Database (Denmark)

    Olesen, Stine Chabert; Hansen, Dorte Lindqvist; Almdal, Thomas;

    2009-01-01

    on appetite-regulating gut hormone, particularly peptide YY and glucagon-like peptide-1. Nevertheless, other unknown hormones or mechanisms may be involved in the dramatic changes in the glucose metabolism. Development of new drugs and treatments based on the endocrine changes observed after bariatric surgery...

  11. Lenalidomid til behandling af transfusionskraevende myelodysplastisk syndrom

    DEFF Research Database (Denmark)

    Risum, Malene; Dufva, I.H.

    2010-01-01

    Lenalidomide is the first drug to induce transfusion independence and cytogenetic remission in patients with myelodysplastic syndrome (MDS) with deletion 5q and low or intermediate risk score. Transfusion independence can be obtained within five weeks. Three out of four patients also obtain...

  12. Diagnostik og behandling af neuromyelitis optica

    DEFF Research Database (Denmark)

    Nielsen, Helle Hvilsted; Ravnborg, Mads; Illes, Zsolt

    2014-01-01

    Neuromyelitis optica (NMO) is an inflammatory demyelinating disease characterized by antibodies against aquaporin-4 in up to 80% of the cases and even less in the NMO spectrum disorders, which may be difficult to distinguish from early multiple sclerosis. While immunosuppressive therapy should...

  13. Vellykket konservativ behandling efter knivtraume mod hjertet

    DEFF Research Database (Denmark)

    Wærsted, Stian; Schou-Jensen, Katrine; Jensen, Tim;

    2012-01-01

    A five year-old girl was admitted to hospital following an accidental stab wound to the chest, inflicted by a knife placed in a dishwasher's cutlery tray. Investigations revealed a traumatic ventricular septum defect of the heart, with a pericardial effusion. Since the patient remained haemodynam...

  14. Moderne behandling af type B-aortadissektion

    DEFF Research Database (Denmark)

    Klitfod, L.; Baekgaard, N.; Just, S.

    2008-01-01

    Rapid classification is essential in the management of aortic dissections, as Type A dissections require surgery, while the optimal treatment of Type B dissections is controversial. Medical treatment with antihypertensive medication and analgesics has so far been the main treatment of uncomplicated...... Type B dissections, while surgery has been reserved for complications and persistent pain in spite of medical treatment. Endovascular techniques are less invasive than open repair and show promising early results Udgivelsesdato: 2008/9/8...

  15. Meckels divertikel. Fra embryologi til behandling

    DEFF Research Database (Denmark)

    Buchvald, F F; Pærregaard, Anders

    2000-01-01

    Meckel's diverticulum (MD), an remnant of the omphalomesenteric duct, is the most common congenital abnormality of the small bowel. The aim of this paper is to give a review of MD, from embryology to diagnosis, complications and treatment.......Meckel's diverticulum (MD), an remnant of the omphalomesenteric duct, is the most common congenital abnormality of the small bowel. The aim of this paper is to give a review of MD, from embryology to diagnosis, complications and treatment....

  16. Udredning og behandling af osteoporotiske hoftefrakturer

    DEFF Research Database (Denmark)

    Eiken, Pia A; Abrahamsen, Bo

    2010-01-01

    INTRODUCTION: Osteoporosis is a major cause of low-energy hip fractures. Although there are pharmacologic agents available for both prevention and treatment, less than 10% of hip fracture cases initiate anti-osteoporotic treatment. MATERIAL AND METHODS: In 1995 and 2008, questionnaires were sent......% in 2008. In 2008, 48% of the departments informed the GPs that their patient with a low-energy fracture may have osteoporosis and that further evaluation and treatment may be needed. CONCLUSION: Medical treatment after fractures was more widespread in 2008 than in 1995. About half of the Danish...... to all Danish orthopaedic surgery departments treating patients with low-energy hip fractures, asking them to explain a) whether patients with osteoporosis are identified, b) whether the patients identified are treated for osteoporosis, and c) whether physicians need more information about osteoporosis...

  17. Udredning og behandling af osteoporotiske hoftefrakturer

    DEFF Research Database (Denmark)

    Eiken, Pia Agnete; Abrahamsen, Bo

    2010-01-01

    Osteoporosis is a major cause of low-energy hip fractures. Although there are pharmacologic agents available for both prevention and treatment, less than 10% of hip fracture cases initiate anti-osteoporotic treatment.......Osteoporosis is a major cause of low-energy hip fractures. Although there are pharmacologic agents available for both prevention and treatment, less than 10% of hip fracture cases initiate anti-osteoporotic treatment....

  18. MINDFULNESS BEHANDLING AF DANSKE VETERANER - ET PILOTSTUDIE

    DEFF Research Database (Denmark)

    Fjorback, Lone

    2015-01-01

    I foråret 2014 mødtes en gruppe på 12 danske veteraner en gang om ugen i 9 uger for at deltage i programmet Mindfulness Baseret Stress Reduktion (MBSR). Deltagerne havde meldt sig frivilligt, og gruppen var blandet mht. alder, køn, antal udsendelser og diagnoser. Det, de havde til fælles, var...

  19. Udredning og behandling af autoimmun encefalitis

    DEFF Research Database (Denmark)

    Blaabjerg, Morten; Mærsk-Møller, Camilla C; Kondziella, Daniel;

    2015-01-01

    Autoimmune encephalitis with antibodies against neuronal surface antigens is diagnosed with increasing frequency in recent years. If treated early and aggressively, these conditions often respond favourably to immunotherapy. We describe the clinical features, diagnosis and treatment of the two mo...

  20. Ipilimumab til behandling af metastaserende melanoma

    DEFF Research Database (Denmark)

    Ghasemi, Habib; Schmidt, Henrik; Stolle, Lars Bjørn

    2015-01-01

    Until recently metastatic melanoma was a disease with limited treatment options and a poor prognosis. However, new promising products have been developed. Ipilimumab, a full human anti-cytotoxic T-lymphocyte antigen-4 antibody, has shown improved survival in several clinical trials and is now...... a part of the standard treatment options for this disease in Denmark. In this case report we present a 78-year-old man with metastatic melanoma who had complete remission after treatment with ipilimumab....

  1. Behandl dig selv med honning"

    DEFF Research Database (Denmark)

    Mejrup, Kristian; Bjerring-Nielsen, Mattias

    2015-01-01

    with a heavenly figure, a potent Joseph lookalike, who reveals to her inexpressible secrets mediated in an exuberant honeycomb. The revelatory capacity of honey is stylistically rendered by means of repetition, pleonasm, chorus, reprises and gestures. The encounter with “Das ganz Andere” does not leave Aseneth...

  2. Autoimmun hepatitis. Fremtroedelsesformer, diagnostik og behandling

    DEFF Research Database (Denmark)

    Poulsen, L O; Tage-Jensen, U; Vyberg, M

    1992-01-01

    a few weeks to years. Seven patients had increased serum aspartate aminotransferase (ASAT) levels. The three patients with normal ASAT levels had hypoalbuminaemia, decreased level of prothrombin or high levels of serum immunoglobulin G. Moderate or high levels of smooth muscle antibody titer were...

  3. Bilateral akillesseneruptur efter behandling med ciprofloxacin

    DEFF Research Database (Denmark)

    Attarzadeh, Amir Pasha; Ryge, Camilla

    2013-01-01

    We report a case of spontaneous non-traumatic bilateral rupture of the Achilles tendons following ciprofloxacin treatment. A 54-year-old man presented with spontaneous Achilles tendon rupture on the left side, tendinitis and partial tear on the right side following few days of treatment with cipr......We report a case of spontaneous non-traumatic bilateral rupture of the Achilles tendons following ciprofloxacin treatment. A 54-year-old man presented with spontaneous Achilles tendon rupture on the left side, tendinitis and partial tear on the right side following few days of treatment...... with ciprofloxacin 500 mg twice daily and long-term treatment with prednisolon 10 mg once daily. This rare side effect caused by concurrent treatment with steroids and ciprofloxacin should be kept in mind. Any signs of tendinitis following this treatment should arouse the physicians' suspicion towards ciprofloxacin....

  4. Operativ behandling af thoracic outlet syndrome

    DEFF Research Database (Denmark)

    Birkeland, Peter; Stiasny, Jerzy

    2012-01-01

    of the brachial plexus. At surgery, we found and severed a fibrous band that compressed the inferior trunk. Postoperatively, the pain subsided and fine hand movements improved. One patient had no cervical rib, however, in the two other cases we found rudimentary cervical ribs. Magnetic resonance imaging......We present three cases with longstanding true neurogenic thoracic outlet syndrome. All patients had aching pain in the shoulder, arm and ulnar border of the hand. On examination, we found atrophy of the hand muscles. Electromyography revealed signs of compromised function of the inferior trunk...

  5. Noninvasiv behandling af slid og erosion

    DEFF Research Database (Denmark)

    Pallesen, Ulla; Dijken, Jan van

    2012-01-01

    Slid og erosion af tænder synes i dag at være et voksende problem for mange patienter. I de fleste tilfælde kan tandlægens tidlige diagnostik føre til, at forebyggende tiltag iværksættes i tide, så fortsatte skader ophører, eller progressionen begrænses. Desværre er det ikke altid muligt, og hvis...

  6. Kirurgisk behandling af urininkontinens hos kvinder

    DEFF Research Database (Denmark)

    Ammendrup, A.C.; Sørensen, Helle Christina; Sander, Pia;

    2010-01-01

    INTRODUCTION: During the last decade, minimal invasive procedures have been introduced for treatment of urinary incontinence (UI) in women leading to shorter hospitalisation and fewer complications. The aim of this study was to outline clinical practice and attitudes among Danish UI surgeons. MAT...

  7. Behandling af diabetes mellitus med biologiske laegemidler

    DEFF Research Database (Denmark)

    Larsen, Claus Morten; Mandrup-Poulsen, Thomas

    2008-01-01

    Biologic therapeutics are currently not approved for the treatment of patients with type 1 and type 2 diabetes. However, promising results from recent randomized controlled studies suggest that biologic therapeutics have therapeutic potential. This article summarizes the causal steps of the patho......Biologic therapeutics are currently not approved for the treatment of patients with type 1 and type 2 diabetes. However, promising results from recent randomized controlled studies suggest that biologic therapeutics have therapeutic potential. This article summarizes the causal steps...... of the pathogenesis of type 1 and type 2 diabetes which are targeted by biologic therapeutics and reviews the treatment results. Udgivelsesdato: 2008-Jun-9...

  8. Momsmæssig behandling af vouchere

    DEFF Research Database (Denmark)

    Christiansen, Randi; Elgaard, Karina Kim Egholm

    2012-01-01

    and a-hydroxysalmeterol during visits one and two were 12.6 and 21.8%, respectively. The intra-individual variability of salmeterol and a-hydroxysalmeterol in the urine concentrations were significantly higher when uncorrected for USG with 43.0 and 43.7% versus 20.4% (p

  9. Behandling af peritonsillær absces

    DEFF Research Database (Denmark)

    Anthonsen, Kristian; Trolle, Waldemar

    2012-01-01

    Peritonsillar abscess (PTA) is associated with high morbidity and can cause serious and life-threatening complications. In Denmark, the most commonly isolated bacteria are Fusobacterium necrophorum and Streptococcus pyogenes gr. A. The incidence of PTA in Denmark is 41/100,000/year, the highest...... incidence ever reported for PTA. There is no definite consensus on the treatment. We recommend most patients treated with puncture and antibiotics as outpatients, and if necessary acute tonsillectomy instead of interval tonsillectomy. Steroids may be of value....

  10. Gruppebaseret behandling af BED - et faseopdelt behandlingstilbud

    DEFF Research Database (Denmark)

    Laust, Jakob; Lau, Marianne Engelbrecht; Waaddegaard, Mette

    2015-01-01

    konsekvenser. BED blev i 2013 optaget i DSM-5 (Diagnostic and Statistical Manual of Mental Disorders) som en selvstændig diagnose og BED forventes medtaget i den forestående revision af det internationale diagnose system, ICD-11. Sundhedsstyrelsen gav på denne baggrund satspuljemidler til erfaringsopsamling...

  11. Kirurgisk behandling af levermetastaser og levercancer

    DEFF Research Database (Denmark)

    Wojdemann, M.; Burcharth, F.; Rokkjaer, M.

    2008-01-01

    Hepatic resection is the golden standard in treatment of tumours from primary liver cancer and colorectal liver metastases, but is appropriate for a variety of other benign and malignant tumours in the liver. The selection of patients and criteria are discussed. Curative liver surgery...

  12. Psykoterapeutisk behandling af emotionelt ustabile personlighedsforstyrrelser

    DEFF Research Database (Denmark)

    Sørensen, Per; Kjølbye, Morten

    2015-01-01

    "Måske er vi samme person. Måske har vi ingen grænser. Måske strømmer vi gennem hinanden ubegrænset og storartet" (Ingmar Bergman, Fanny og Alexander, 1980)......."Måske er vi samme person. Måske har vi ingen grænser. Måske strømmer vi gennem hinanden ubegrænset og storartet" (Ingmar Bergman, Fanny og Alexander, 1980)....

  13. Udredning og behandling af morbus Osler

    DEFF Research Database (Denmark)

    Kjeldsen, Anette Drøhse; Andersen, Poul Erik; Tørring, Pernille Mathiesen

    2011-01-01

    such as pulmonary arteriovenous malformations (PAVM), cerebral arteriovenous malformations (CAVM) and gastrointestinal bleeding. Collaboration between various medical specialties is essential in order to provide an up-to-date treatment and thorough work-up in the individual patient. Disregard of symptoms may result...

  14. Biofarmaka til behandling af reumatoid artritis

    DEFF Research Database (Denmark)

    Baslund, Bo; Bendtzen, Klaus

    2008-01-01

    The current status on the use of biopharmaceuticals in the treatment of rheumatoid arthritis is reviewed. Blocking of TNF-alpha, co-stimulation of CD28+ T-cells and depletion of CD20+ B-cells are all effective ways to diminish inflammation and joint damage. However, not all patients react to thes...

  15. Abatacept til behandling af reumatoid artritis

    DEFF Research Database (Denmark)

    Nielsen, Henrik; Hansen, Annette

    2009-01-01

    Abatacept (CTLA4Ig) is a human fusion protein which consists of a cytotoxic lymphocytic-associated type 4 antigen which is bound to the Fc part of the IgG1. Abatacept binds to CD80/CD86 on antigen-presenting cells thus blocking the co-stimulatory signal to the naïve T cells and interfering with a...

  16. Udvikling af medicinsk behandling mod bipolar lidelse

    DEFF Research Database (Denmark)

    Ellegaard, Pernille Kempel

    2015-01-01

    Selvom Esbjerg ligger i vandkants Danmark, er det den Psykiatriske Forskningsenhed i denne by, der er primus motor for et stort forsøg blandt mennesker, der lider af bipolar lidelse. Forsøget hedder ”NACOS”, og er et medicinsk forsøg til mennesker, der befinder sig i den depressive fase.......Selvom Esbjerg ligger i vandkants Danmark, er det den Psykiatriske Forskningsenhed i denne by, der er primus motor for et stort forsøg blandt mennesker, der lider af bipolar lidelse. Forsøget hedder ”NACOS”, og er et medicinsk forsøg til mennesker, der befinder sig i den depressive fase....

  17. Behandling med kosmetiske bløddelsfyldere

    DEFF Research Database (Denmark)

    Thyssen, Jacob Pontoppidan; Christensen, Lise H; Zachariae, Claus O C

    2007-01-01

    An increasing number of patients undergo soft-tissue augmentation. The quality depends on the applied filler substance, the compliance of the patient and the physician. Long-term adverse reactions are referred to as nodules or granulomas. Nodules following degradable gels and polyacrylamide hydro...

  18. Nationale domstoles behandling af internationale normkonflikter

    DEFF Research Database (Denmark)

    Kjeldgaard-Pedersen, Astrid

    2013-01-01

    Med sin dom af 12. september 2012 i sagen Nada v. Switzerland har Den Europæiske Menneskerettighedsdomstol (EMD) givet ny næring til debatten om, hvordan konflikter mellem staters forpligtelser ifølge Den Europæiske Menneskerettighedskonvention (EMRK) og deres forpligtelser efter bindende...

  19. Neurointensiv behandling af svaere traumatiske hjerneskader

    DEFF Research Database (Denmark)

    Welling, Karen-Lise Kobberø; Eskesen, Vagn; Romner, Bertil;

    2010-01-01

    We present a Danish algorithm for the neurointensive care of patients with severe traumatic brain injury. The primary goal is to avoid cerebral ischaemia and hypoxia and secondarily brain injury. Patient evaluation by a neurosurgeon is mandatory, and decision-making concerning extended cerebral m...... monitoring should take place immediately. Treatment aiming at diminishing increased intracranial pressure should be initiated early. Early critical care management of patients with severe traumatic brain injury should be performed in a teamwork comprising various specialties....

  20. Behandling af ideopatisk hypereosinofilt syndrom med imatinib

    DEFF Research Database (Denmark)

    Sørensen, Anne Louise; Larsen, Herdis

    2008-01-01

    We here report a case of idiopathic hypereosinophilic syndrome with prompt response to treatment with imatinib. The patient presented with chest pain, myalgias, fatigue and weakness. Blood tests and bone marrow examination revealed striking eosinophilia. Clonal or reactive disorders were excluded...

  1. Flumazenil til behandling af hepatisk encefalopati

    DEFF Research Database (Denmark)

    Elkjaer, J M; Jensen, T U; Emborg, J

    2000-01-01

    Hepatic encephalopathy (HE) is the neuropsychiatric syndrome that occurs as a complication to liver failure in patients with acute or chronic liver disease. Mental status in this syndrome can range from subtle deficits to coma, with respiratory insufficiency and aspiration to the lungs. The morta......Hepatic encephalopathy (HE) is the neuropsychiatric syndrome that occurs as a complication to liver failure in patients with acute or chronic liver disease. Mental status in this syndrome can range from subtle deficits to coma, with respiratory insufficiency and aspiration to the lungs....... Transient improvement of the condition is seen in a subgroup of patients after administration of flumazenil, a specific benzodiazepine antagonist. The group of patients with a positive response to flumazenil therapy may have a better prognosis. Flumazenil may be used in patients in the pretransplantation...

  2. Construction of a methodologically consistent time series of substance loads and their impacts in Germany. Pt. 2. Final report; Erstellung einer methodenkonsistenten Zeitreihe von Stoffeintraegen und ihren Wirkungen in Deutschland. T. 2. Abschlussbericht. Projektteile: (1) Kartierung von Deposition Loads fuer das Prognose-Jahr 2020: Modellierungs- und Kartierungsergebnisse, Kartenabbildungen, Grafiken und regionale Statistik. (2) Berechnung und Kartierung von Critical Loads und deren Ueberschreitungen fuer eine prognostizierte Deposition im Jahr 2020. Genfer Luftreinhaltekonvention der UNECE

    Energy Technology Data Exchange (ETDEWEB)

    Gauger, Thomas [Stuttgart Univ. (Germany). Inst. fuer Navigation; Nagel, Hans-Dieter; Schlutow, Angela; Scheuschner, Thomas [OEKO-DATA Gesellschaft fuer Oekosystemanalyse und Umweltdatenmanagement mbH, Strausberg (Germany)

    2013-01-15

    The contribution under consideration reports on the total deposition of anthropogenic emitted oxidized sulphur compounds, oxidized nitrogen compounds and reduced nitrogen compounds based on the emission prognosis of the BMU/UBA project 'Strategies for the reduction of the fine dust pollution for the year 2020. The emission prognoses are the fundament for the calculations with the LOTOS-EUROS model. The changes of the total deposition for sulphur compounds as well as nitrogen compounds between the years 2005 and 2020 are not large. For example, the total deposition of oxidized sulphur compounds from anthropogenic sources in the year 2020 is about 35% larger in comparison to the year 2005. In comparison to the year 2005, the total deposition of oxidized nitrogen compounds from anthropogenic sources in the year 2020 is about 21% larger.

  3. Beta-agonisten : stand van zaken en prognoses

    NARCIS (Netherlands)

    Schilt, R.; Haasnoot, W.; Huf, F.A.

    1990-01-01

    Op dit moment zijn de Beta-agonisten clenbuterol, mabuterol, salbutamol, cimalerol en terbutaline zowel met een multi-screeningsmethode als met een multi-bevestigingsmethode te bepalen. Op korte termijn is te verwachten dat de Beta-agonisten bamethaan, orciprenaline (= metaproterenol) en isoproteren

  4. Forskelle mellem hospitaler i prognose efter hjertestop uden for hospital

    DEFF Research Database (Denmark)

    Kjaergaard, Jesper; Bro-Jeppesen, John; Rasmussen, Lars Simon;

    2009-01-01

    INTRODUCTION: There are substantial differences in long-term survival of patients resuscitated from out-of-hospital cardiac arrest, and the level of care during hospitalization may be a contributing factor. The purpose of this study was to determine if a difference in long-term prognosis between ...

  5. Prognosis renewable energy. 2013 report; Prognose hernieuwbare energie. Rapportage 2013

    Energy Technology Data Exchange (ETDEWEB)

    Neeft, J.; Dijkstra, J.; Van Erp, F.; Leguijt, T.

    2013-10-15

    A prognosis for the estimate share of renewable energy in the upcoming years in the Netherlands, including bottlenecks and risks [Dutch] Een vooruitblik op het geschatte aandeel hernieuwbare energie voor de komende jaren, inclusief knelpunten en risico's.

  6. Forbedret prognose ved letkædenefropati ved myelomatose

    DEFF Research Database (Denmark)

    Juul, Jakob Søgaard; Larsen, Thomas; Marcussen, Niels

    2012-01-01

    A 64 year-old woman with acute renal failure and cast nephropathy due to excessive production of lambda free light chains received chemotherapy (using bortezomib and dexamethason) and haemodialysis with a high cut off-filter. The concentration of free light chains was markedly reduced after...... a fortnight. Nine months after admission, the patient's kidney function had improved and dialysis was stopped. Three months later, she got an autologous stem cell transplantation. One year later, estimated glomerular filtration rate was 25 ml/min, and the production of free light chains was under control....

  7. Forebyggelse og behandling af osteoporose i forbindelse med behandling af ikke-metastaserende prostatacancer

    DEFF Research Database (Denmark)

    Eiken, Pia Agnete; Langdahl, Bente Lomholt; Eiken, Frederik L;

    2011-01-01

    The prevention of cancer treatment-induced bone loss in patients with prostatae cancer due to gonadotropin-releasing hormone (GnRH)-agonist, GnRH-antagonist and orchidectomi therapy has a high priority. We present an algorithm for the prevention and treatment of osteoporosis during treatment of non...

  8. 刍议胃溃疡穿孔的不同手术临床治疗方法及预后效果的比较%Discussion on Different Surgical Methods for Patients with Gastric Ulcer Perforation and Comparison of the Prognoses

    Institute of Scientific and Technical Information of China (English)

    葛晓伟

    2015-01-01

    Objective To discuss the different surgical methods for gastric ulcer perforation and compare the prognoses. Methods 60 patients with gastric ulcer perforation from June 2011 and June 2014 were randomly selected in this clinical research and randomly divided into observation group and control group with 30 in each one. The 30 patients in the obser-vation were treated with laparoscopic minimally invasive surgery, while the other 30 in the control group were treated with traditional open surgery. The clinical efficacy and patients' postoperative quality of life were observed in both the two groups, and the outcome was analyzed and discussed. Results All the 30 patients in the observation group were cured with-out complications including postoperative re-perforation and intestinal obstruction; 25 were cured and 5 experienced post-operative complication in the control group, and the difference between the data above of the two groups was statistically significant, P﹤0.05. Conclusion Among the different surgical methods for gastric ulcer perforation, laparoscopic minimally invasive surgery is most commonly used in clinical practice, which can produce good clinical efficacy and prognosis.%目的:探讨胃溃疡穿孔的不同手术临床治疗方法及预后效果。方法从2011年6月-2014年6月,随机抽取60例胃溃疡穿孔患者作为临床研究对象,随机分为观察组和对照组各30例,观察组的30例胃溃疡穿孔患者使用腹腔镜微创手术进行治疗,对照组中30例胃溃疡穿孔患者使用传统开腹手术进行手术治疗;观察两组的治疗效果并观察患者术后的生活品质,将结果进行分析讨论。结果观察组治愈30例,无术后再穿孔或肠梗阻等并发症发生;对照组治愈25例,5例患者有术后并发症情况发生。 P<0.05,两组比较数据结果差异有统计学意义。结论在治疗胃溃疡穿孔患者的不同手术临床治疗方法中,临床常用的治疗方法

  9. The Study of Predicting the Prognoses of Patients in Conscious Disturbance with N20 of Somatosensory Evoked Potential%体感诱发电位N20评价意识障碍患者预后的研究

    Institute of Scientific and Technical Information of China (English)

    黎振声; 彭海燕; 黄永君; 刘雁

    2011-01-01

    Aim: To evaluate the quantitative information ofN20, a main component of SEP, in the prognosis ofpatients with conscious disturbance after a year. Methods: N20 data and clinic cases histories of the patients with conscious disturbance caused by different factors form July 2005 to July 2009 were retrospectively reviewed. Different statistical methods such as t test, Mann-Whitney U test, X 2 test, ROC curves, Kaplan-Meier analysis were used to compare the parameters ofbilateral N20 between the awakened group and the unawakened group and to estimate the patients ' prognosis. Results: Bilateral N20 could be used to predict the prognosis of patients with conscious disturbance (the area under ROC curve of C3 ' -N20 latency occupied 77.6% and the area under ROC curve of C4 ' -N20 latency occupied 79.3%). The bilateral average N20 latencies of the patients still in conscious disturbance were statistically longer than the ones of the patients could have been awaken, however there was no statistical difference in bilateral N20 amplitudes between the two groups. The sensitivity and specificity were 70.8% and 75.0% separately at the point of C4 ' -N20 latency being 20.05 ms which was the best estimated and 75.0% and 72% separately at the point of C4 ' -N20 latency being 19.95 ms. The prognosis of the patients in conscious disturbance with C3' -N20 latency<19.95 ms and C4 ' -N20 latency<20.05 ms after one year were the best, with the smallest percentage of the patients still in conscious disturbance 1 year later and the shortest average time which they took to recover from conscious disturbance. Conclusion: The bilateral N20 latencies are considered as an accurate index to predict the prognoses ofpatients with conscious disturbance, when the patients with bilaterally N20 existent had the best outcomes. The point of C3 ' -N20 latency being 19.95 ms and the point of C4' -N20 latency being 20.05 ms were considered as the best boundaries that could separate the

  10. CA153与CEA在三阴乳腺癌及非三阴乳腺癌预后中的比较分析%Serum CA153 and CEA for prognosing triple negative and non-triple-negative breast cancer

    Institute of Scientific and Technical Information of China (English)

    黄江玲; 邱少雄; 肖亮生; 陈乐川; 杨馥彦

    2015-01-01

    Objective To explore the differences in the serum levels of CA153 and CEA between triple negative and non-triple-negative breast cancer and to analyze the correlation between the serum levels of CA153 and CEA and the patients' prognosis.Methods 120 patients with triple negative breast cancer (triple negative group) and 575 patients with non-triple-negative breast cancer (non-triple-negative group) diagnosed by clinical pathology were selected and their serum levels of CA153 and CEA were detected by electrochemical luminescence.The correlation between these two indicators' serum levels and the patients' overall survival (OS) and progression-free surial (PFS) was analyzed.Results The serum level of CA153 was (47.06±45.63)U/ml in the triple negative group and was significantly higher than that in the non-triple-negative group[(30.38±28.57) U/ml],with a statistical difference(P<0.01).The serum level of CEA was (10.11±9.54)U/ml in the triple negative group and higher than that in the non-triple-negative group[(7.03±6.87)ng/ml] (P < 0.05).5 years' survival analysis showed that the patients with triple negative breast cancer whose serum CA 153 < 47.06 U/ml and CEA < 10.11 ng/ml and the patients with non-triplenegative breast cancer whose serum CA153< 30.38 U/ml and CEA < 7.03 ng/ml has advantage in OS and PFS,with statistical differences(P < 0.05).Conclusions CA153 and CEA can be used as predictors for prognosing triple negative and non-triple-negative breast cancer.%目的 探讨血清CA153与CEA在三阴乳腺癌及非三阴乳腺癌中表达水平的差异,并分析血清中CA153与CEA水平差异与患者预后情况的关系.方法 选取2005年1月至2012年6月经临床病理学确诊的三阴乳腺癌患者120例(三阴组)及非三阴乳腺癌患者575例(非三阴组),采用电化学发光法检测两组患者血清CA153、CEA含量,并分析这两种肿瘤标志物水平变化与患者总生存期、无进展生存期的关系.结果

  11. Palliativ behandling af patienter med terminal kronisk obstruktiv lungesygdom

    DEFF Research Database (Denmark)

    von Plessen, Christian; Nielsen, Thyge L; Steffensen, Ida E;

    2011-01-01

    Terminal chronic obstructive pulmonary disease (COPD) and advanced cancer have similar prognosis and symptom burden. However, palliative care of patients with terminal COPD has been neglected in Denmark. We describe the symptoms of terminal COPD and suggest criteria for defining the palliative...... phase of the disease. Furthermore we discuss the prognostic and ethical challenges for patients, their families and their caregivers. Finally, we summarize the current evidence for palliative treatment of dyspnoea and ways to evaluate response to treatment....

  12. Medicinsk behandling af vandladningsproblemer hos mænd

    DEFF Research Database (Denmark)

    Andersen, Jens Thorup; Nordling, Jørgen; Walter, Steen

    2007-01-01

    Lower Urinary Tract Symptoms (LUTS) e.g. in prostatic infravesical obstruction and symptoms of overactive bladder (OAB) in men can be treated effectively with drugs. The current evidence for use of alpha-adrenergic blocking agents, 5-alpha-reductase inhibitors, combination therapy and antimuscari...... by the administration of a loop-diuretic in the late afternoon. Udgivelsesdato: 2007-May-14...

  13. Nyrepåvirkning ved behandling af hjertesvigt

    DEFF Research Database (Denmark)

    Rasmussen, Zhiying Zhang; Barfod, Toke; Klit, Jakob

    2009-01-01

    The case of a 66-year-old male with heart failure and cardiorenal syndrome is presented. The patient had normal renal function before intensive treatment with diuretics and ACE inhibitor. Shortly after the ACE inhibitor was stopped and diuretics were either stopped or reduced in dosage, his renal...

  14. Apoptose ved kronisk inflammatorisk tarmsygdom. Betydning for patogenese og behandling

    DEFF Research Database (Denmark)

    Seidelin, Jakob Benedict; Nielsen, Ole Haagen

    2003-01-01

    Inflammatory bowel disease (IBD) is characterized by the increased survival of lamina propria leucocytes and ulcerations and an increased epithelial leakiness that compromise the barrier function of the epithelial lining. Deregulated apoptosis seems to be a major cause of the impaired barrier fun...

  15. Stor forskel i behandling af depression mellem psykiatriske afdelinger

    DEFF Research Database (Denmark)

    2010-01-01

    A large proportion of patients admitted to psychological departments and wards suffer from depression. Knowledge is limited about the clinical aspects and treatment of depression at admission and discharge, as well as about the differences between psychiatric hospitals. The purpose of this study...

  16. Tiotropium. Nyt antikolinergikum til behandling af kronisk obstruktiv lungesygdom

    DEFF Research Database (Denmark)

    Pedersen, Steffen Thirstrup; Lange, Peter

    2003-01-01

    Tiotropium is a new anti-cholinergic drug with a long duration of action designed for maintenance treatment of chronic obstructive pulmonary disease (COPD). Tiotropium is the first drug specifically developed for the treatment of COPD, but it is also amongst the most expensive drugs used for this......Tiotropium is a new anti-cholinergic drug with a long duration of action designed for maintenance treatment of chronic obstructive pulmonary disease (COPD). Tiotropium is the first drug specifically developed for the treatment of COPD, but it is also amongst the most expensive drugs used...

  17. Filetlap til behandling af livstruende tryksår

    DEFF Research Database (Denmark)

    Gunnarsson, Gudjon Leifur; Høimyr, Hilde; Rossi, Paolo Emilio

    2014-01-01

    A 71-year-old multi-morbid, paraplegic male with five pressure ulcers and a left-sided open trochanter fracture with chronic osteomyelitis was admitted to hospital. His condition required exarticulation of the left hip joint. A radical wound revision and a pedicled lower extremity fillet flap...... reconstruction of the defect was performed. The patient made uneventful recovery to normal activity within six weeks and had a stable result after one year follow-up. The case is a reminder of the importance of early intervention and preventive management of pressure ulcers and elaborates the benefits...... of interdisciplinary team efforts in the treatment of advanced ulcers....

  18. Gener efter behandling af almindeligt forekommende akutte øjenlidelser

    DEFF Research Database (Denmark)

    Krogsgaard, M R; Danborg, L; Jensen, P;

    1990-01-01

    and 75% within 48 hours. 10% had symptoms for more than a week. Cases of infectious conjunctivitis and trauma to the eye (without intrabulbar lesion) had the highest risk of developing symptoms after the consultation. The lowest incidence of complaints was seen among patients in whom a foreign body...... was removed from the cornea or conjunctiva. The longest duration of symptoms was seen among patients with infectious conjunctivitis. Cases with a foreign body on the cornea or conjunctiva or trauma to the eye (without intrabulbar lesion) had a slightly longer duration of the symptoms when a corneal tear......The aim of the study was to determine the duration of symptoms in patients treated in the emergency room at Glostrup Hospital for acute eye-trouble. Nine common diagnoses were selected for the study. All patients seen during a 2 1/2 month period were asked to complete a questionnaire one week after...

  19. Behandling af metforminassocieret laktatacidose med hæmodialyse

    DEFF Research Database (Denmark)

    Schousboe, K.; Rasmussen, K.; El Fassi, D.;

    2012-01-01

    Metformin-associated lactate acidosis is rare but serious and characterized by metabolic acidosis and elevated lactate. We describe a single-institution experience of four cases in one year. Despite pH levels of 6.85 to 7.12 and lactate levels of 11-28 mmol/l three of the patients survived. Two...... of the patients had normal kidney function previous to hospitalization. Treatment includes fluid replacement, IV sodium bicarbonate and haemodialysis....

  20. Diagnostik og behandling af paroksystisk supraventrikulær takykardi

    DEFF Research Database (Denmark)

    Rujic, Dragana; Sundbøll, Jens; Tofig, Bawer Jalal;

    2016-01-01

    The paroxysmal supraventricular tachycardias (SVT) are commonly encountered arrhythmias and include atrioventricular nodal re-entrant tachycardia, atrioventricular reciprocating tachycardia, and focal atrial tachycardia. These tachycardias share several clinical features as well as similar...... management strategies. The probable mechanism of paroxysmal SVT can often be diagnosed from the clinical findings and a 12-lead ECG. This review describes the initial evaluation and treatment of patients with paroxysmal SVT, including distinctive features from the most important differential diagnoses....

  1. Antibiotika som primær behandling af appendicitis

    DEFF Research Database (Denmark)

    Hupfeld, Line; Pommergaard, Hans-Christian; Burcharth, Jakob;

    2014-01-01

    Acute appendicitis has traditionally been treated surgically. Conservative approach with antibiotic treatment has been suggested as an alternative to the surgical procedure. The available studies on surgery versus antibiotics may indicate the safe use of conservative treatment for uncomplicated...... appendicitis, but the available studies are typically of low quality. Thus, further studies are needed to clarify the role of conservative treatment, and in the meantime appendectomy remains the standard treatment for acute appendicitis....

  2. Behandling af peritoneal karcinose med laparoskopisk intraperitoneal kemoterapi under tryk

    DEFF Research Database (Denmark)

    Graversen, Martin; Pfeiffer, Per; Mortensen, Michael Bau

    2016-01-01

    Pressurized intraperitoneal aerosol chemotherapy (PIPAC) is a new treatment option in patients with peritoneal carcinomatosis (PC). PIPAC has proven efficacious in the treatment of PC from ovarian, colon and gastric cancer. PIPAC has a favourable profile regarding safety for patients and occupati......Pressurized intraperitoneal aerosol chemotherapy (PIPAC) is a new treatment option in patients with peritoneal carcinomatosis (PC). PIPAC has proven efficacious in the treatment of PC from ovarian, colon and gastric cancer. PIPAC has a favourable profile regarding safety for patients...

  3. Pankreas øytransplantasjon som behandling for diabetes mellitus

    OpenAIRE

    2007-01-01

    ABSTRACT. Background. Results in pancreatic islet transplantation have improved during the last decade, but long term results remain disappointing. This is partly due to loss of islets in pre-transplant culture and immediate post-transplant period. Aim. Exendin is currently being used as drug therapy of type 2 diabetes mellitus. We wanted to investigate the in vitro effect of exendin on insulin secretion, pro- and anti-inflammatory cytokines in isolated pancreatic islets from rats. ...

  4. Utilfredsstillende langtidsresultater efter konservativ behandling af patellofemoralt smertesyndrom

    DEFF Research Database (Denmark)

    Rathleff, Michael Skovdal; Rasmussen, Sten; Olesen, Jens Lykkegaard

    2012-01-01

    This review overviews the long-term prognosis of conservatively treated patients with patellofemoral pain syndrome (PFPS). Median values of the 16 included studies show that 29% of soldiers, 27.8% of sports active and 24,7% of the general public will become pain free after they are diagnosed...

  5. Legionella pneumoni hos patienter, der er i behandling med infliximab

    DEFF Research Database (Denmark)

    Vinter, Hanne; Nielsen, Henrik Ib

    2009-01-01

    Therapy with tumour necrosis factor-alfa inhibitors is widely used in various inflammatory disorders, but adverse events from severe infections with intracellular pathogens may occur. We describe two cases of severe pulmonary legionellosis in patients treated with infliximab for Crohn's disease a...... and psoriasis, respectively. We conclude that legionella infections are probably more frequent in patients receiving immunosuppressive therapy with tumour necrosis factor-alfa inhibitors than in the background population. Udgivelsesdato: 2009-Jan-19...

  6. Farmakologisk behandling af mild ukompliceret hypertension i almen praksis

    DEFF Research Database (Denmark)

    Paulsen, Maja Skov; Christensen, Bo; Søndergaard, Jens

    2013-01-01

    Hypertension is an important risk factor for cardiovascular disease. In Denmark, patients with hypertension are primarily managed in primary care. A recent Cochrane review concluded that pharmacotherapy of patients with mild hypertension (systolic blood pressure 140-159 mmHg; diastolic blood...... pressure 90-99 mmHg; no diabetes or cardiovascular disease) did not reduce mortality or morbidity. The evidence for pharmacotherapy in patients having mild/uncomplicated hypertension is weak. However, current Danish guidelines have taken this into consideration in their recommendations of pharmacotherapy...

  7. Graviditet i livmoderhalsen kan behandles konservativt med methotrexat

    DEFF Research Database (Denmark)

    Sørensen, Marie; Clausen, Helle Vibeke

    2011-01-01

    Two cases of cervical ectopic pregnancy after in vitro fertilization embryo transfer were managed conservatively. One living cervical ectopic pregnancy was treated with intra-amniotic and systemic injection of methotrexate, and the other cervical ectopic pregnancy with a fetal pole was treated...... with systemic methotrexate. The patient with the living cervical ectopic pregnancy had stable vital signs during the period of treatment. The patient with the fetal pole was admitted with heavy vaginal bleeding and anaemia and was stabilised before treatment was initiated. She was stable throughout...

  8. Biologisk behandling af neuroendokrine tumorer i mave-tarm-kanalen

    DEFF Research Database (Denmark)

    Hansen, Carsten Palnaes; Knigge, Ulrich

    2008-01-01

    Biotherapy of hormonal symptoms and tumour growth is a mainstay in the therapy of metastatic neuroendocrine tumours of the gastrointestinal tract and pancreas. Symptomatic relief can be achieved by somatostatin analogues and interferon, either alone or in combination. The effect on tumour growth...... is less convincing although a stabilization of disease is recorded in almost 50% of patients. Interferon treatment should mainly be considered for tumours with a low proliferation index....

  9. Der er store barrierer for psykiatrisk behandling i lavindkomstlande

    DEFF Research Database (Denmark)

    Sørensen, Carina Winkler; Bæk, Ole; Carlsson, Jessica;

    2015-01-01

    resources and ineffective health organization. Human resources are inadequate, and often drugs are not available. Individuals face long distances to psychiatric hospitals, out-of-pocket payment and stigma. There is a great need for research in how to enhance prevention and treatment of mental disorders...

  10. Laktatacidose ved behandling af type 2-diabetes med metformin

    DEFF Research Database (Denmark)

    Holst, Helle; Eldrup, Ebbe; Guldstad, Nana Harriet;

    2012-01-01

    Metformin (MET) is the first-line agent in treatment of type 2 diabetes. However, MET has been associated with lactic acidosis (MALA), a potential but rare complication which has influenced treatment strategies in decades. Recently, guidelines have been changed in regards of age and heart failure...

  11. Antitrombotisk behandling ved iskaemisk apopleksi og transitorisk cerebral iskaemi

    DEFF Research Database (Denmark)

    Overgaard, Karsten; Poulsen, Tina Svenstrup; Husted, Steen E

    2007-01-01

    includes anticoagulation in patients with cardioembolic stroke and antiplatelet agents aspirin possibly combined with dipyridamole or clopidogrel alone in patients with non-cardioembolic stroke. Other individual risks may modify this treatment regimen. Udgivelsesdato: 2007-Oct-1......In acute ischemic stroke and transient ischemic attack (TIA), aspirin is recommended to all patients (except immediately following thrombolysis). Heparin and anticoagulant therapy using vitamin K antagonists should be avoided in the acute phase. Secondary preventive antithrombotic treatment...

  12. Behandling af pilonidalcyster med neodynium-yttriumaluminiumgranat-laser

    DEFF Research Database (Denmark)

    Lindholt, Christine S; Lindholt, Jes Sanddal; Lindholt, Jan

    2008-01-01

    A 23 year-old woman with a nonsupporative pilonidal cyst was successfully treated causally with Nd-YAG laser, and without any recidivate after 9 months follow-up. The mechanism is presumed to be that YAG-laser has a wave-length of 1064 nm. Consequently, the wave penetration through the skin is de...... is deeper than most other lasers before the energy is absorbed in melanin and oxyhaemoglobin, so the contents of the cyst can be reached and destroyed. The treatment could be a very attractive alternative to open surgery....

  13. Behandling af pilonidalcyster med neodynium-yttriumaluminiumgranat-laser

    DEFF Research Database (Denmark)

    Lindholt, Christine S; Lindholt, Jes S; Lindholt, Jan

    2008-01-01

    A 23 year-old woman with a nonsupporative pilonidal cyst was successfully treated causally with Nd-YAG laser, and without any recidivate after 9 months follow-up. The mechanism is presumed to be that YAG-laser has a wave-length of 1064 nm. Consequently, the wave penetration through the skin is de...... is deeper than most other lasers before the energy is absorbed in melanin and oxyhaemoglobin, so the contents of the cyst can be reached and destroyed. The treatment could be a very attractive alternative to open surgery. Udgivelsesdato: 2008-Jun-23...

  14. Linezolid som behandling af infektiøs endokarditis

    DEFF Research Database (Denmark)

    Lauridsen, Trine Kiilerich; Arpi, Magnus; Bruun, Niels Eske

    2010-01-01

    In Denmark enterococci causes 15 to 20% of all endocarditis (IE) cases. The development of multi-resistant bacterial strains has increased the need for new antibiotics. Linezolid is an alternative to conventional treatment of infections with gram positive cocci. In this case report linezolid was ...... was used to treat IE in a patient, who was allergic to penicillin and where conventional treatment caused development of acute renal failure. No side effects were observed and the patient responded well to the treatment....

  15. Kirurgisk behandling af fedme hos børn

    DEFF Research Database (Denmark)

    Hansen, Ann Berit; Gögenur, Ismail; Støckel, Mikael

    2014-01-01

    Morbid obesity in teenagers has become an increasing problem. Conventional diet has not yet shown effective long-term weight loss. Alternatively, bariatric surgery on adolescents has resulted in substantial weight loss, recovery from diabetes, improvement of cardiovascular risk factors...... and improvement in psychosocial status. Still, surgery performed on adolescents provides ethical challenges such as the unknown long-term prognosis after surgery. Despite these challenges, in cases of severe intractable obesity or development of life-threatening complications due to obesity, surgery should...

  16. Diagnostik og behandling af næsefraktur hos voksne

    DEFF Research Database (Denmark)

    Sjöstedt, Sannia; Larsen, Christian Grønhøj; Bilde, Anders;

    2016-01-01

    The risk of complications warrants treatment of most dislocated nasal fractures. Other injuries including other facial fractures and septal haematoma must be treated if present at the initial presentation. The usual treatment for a simple nasal fracture is closed reduction in local anaesthesia...... after five to seven days. Complicated cases require open reduction in general anaesthesia. Later revision of the deviated nose may become necessary in patients suffering from complications such as persistent nasal stenosis and/or deformity....

  17. Måling af nyrefunktion under cytostatisk behandling

    DEFF Research Database (Denmark)

    Hartlev, Louise Brøndt; Bøje, Charlotte Rotbøl; Bluhme, Henrik;

    2008-01-01

    INTRODUCTION: Some cytostatics, used in the treatment of cancer, are excreted by the kidneys and may be nephrotoxic. The glomerular filtration rate (GFR) represents a method for reliable assessement of the 51Cr-EDTA plasma clearance before and during treatment with nephrotoxic drugs. The aim...... of this retrospective study was to evaluate whether this method could be replaced by a more simplified GFR estimate calculated from the creatinine plasma concentration. MATERIALS AND METHODS: We included all patients who had had at least four GFR measurements in 2005 as part of their nephrotoxic cytostatic treatment....... The estimated GFR (eGFR) was calculated from sex, age and weight, according to the Cockcroft formula. RESULTS: Forty-eight patients with a mean age of 47 years were included. 51Cr-EDTA plasma clearance and eGFR showed a poor correlation (r(2) = 0,678). On average, GFR decreased from 95 ml/min to 80 ml/min from...

  18. Diagnose og behandling af cerebral venøs sinustrombose

    DEFF Research Database (Denmark)

    Birkeland, Peter; Stilling, Margit Vejen; Høgedal, Lisbeth

    2015-01-01

    antagonists for three months or more. In fulminant cases local thrombolysis is administered, while symptomatic treatment for increased intracranial pressure is given. In retrospective analyses this approach has been associated with a good outcome – even in cases treated by decompressive craniectomy....

  19. Tyndtarmstransplantation som behandling af tarmsvigt hos børn

    DEFF Research Database (Denmark)

    Thøstesen, Lisbeth Marianne; Qvist, Niels; Rasmussen, Allan

    2010-01-01

    Parenteral nutrition is the main treatment of intestinal failure. In cases with irreversible intestinal failure and life-threatening complications to parenteral nutritional treatment, transplantation of the intestine may be considered. Post-transplantation survival has increased markedly during...

  20. Endoventrikulaer venstre ventrikel-rekonstruktion til behandling af hjerteinsufficiens

    DEFF Research Database (Denmark)

    Funder, Jonas Amstrup; Klaaborg, Kaj-Erik; Egeblad, Henrik;

    2009-01-01

    ventricular restoration was performed in 26 patients (23 males) with a median age of 64 years (47-74 years). Twenty-one of the patients were in New York Heart Association (NYHA) class III-IV. The median preoperative left ventricular ejection fraction was 27% (13-38%). We collected both pre- and postoperative...... had increased to 35% (18-53%) (p class I-II (p

  1. Hvorfor og hvornår behandles aktiniske keratoser

    DEFF Research Database (Denmark)

    Wulf, Hans Christian Olsen

    2014-01-01

    in the hyperkeratotic AK. Visible AK and neighbouring invisible AK should be treated. As AK are provoked by UV radiation, protection against UV is essential. This paper comments on a Cochrane review: "Interventions for actinic keratosis" and treatments avaliable in Denmark...

  2. Ranolazin--ny behandling af kronisk stabil angina pectoris

    DEFF Research Database (Denmark)

    Ahlehoff, Ole; Hansen, Peter Riis

    2009-01-01

    Ranolazine sustained-release tablets were recently approved in the EU for chronic stable angina as add-on therapy when symptoms are not controlled with first-line agents. The mechanism of action is thought to involve inhibition of late sodium influx in the heart, which can reduce abnormalities...... of contractility and repolarisation associated with ischaemia. Ranolazine increases the exercise capacity, reduces angina, and diminishes the use of nitroglycerine. The drug has an excellent safety profile and may be a valuable addition to the treatment of chronic stable angina....

  3. Den haemostatiske balance under behandling med nyere p-pillepraeparater

    DEFF Research Database (Denmark)

    Petersen, K R; Skouby, S O; Sidelmann, Johannes Jakobsen

    1994-01-01

    of fibrinogen and factor VII increased while the capacity of coagulation inhibition was affected by increased protein C and decreased protein S levels. Increased fibrinolytic capacity was indicated by elevated activity and reduced antigen levels of tissue plasminogen activator and reduced activity...

  4. Medicinsk behandling af små abdominale aortaaneurismer

    DEFF Research Database (Denmark)

    Høgh, Annette Langager; Sandermann, Jes; Lindholt, Jes S

    2008-01-01

    such as prevention for cardiovascular disease has a spin-off benefit by suppressing the expansion rate of AAAs. According to these studies ACE inhibitors, statins and nonsteroidal anti-inflammatory drugs may have effect, macrolides may have some effect while beta-blockers and calcium-channel blockers have no effect...

  5. Bivirkninger ved N-acetylcystein-behandling af paracetamolforgiftede patienter

    DEFF Research Database (Denmark)

    Schmidt, L E; Dalhoff, K P

    1999-01-01

    Treatment of paracetamol intoxication with N-acetylcysteine (NAC) is standard in Denmark. NAC is considered safe with relatively few side effects. It is recommended that all patients be treated irrespective of paracetamol dose or time from intoxication to treatment start. Consequently a higher nu...

  6. Salmonella typhi--tid til aendring af den empiriske behandling

    DEFF Research Database (Denmark)

    Gade, Christina; Engberg, Jørgen; Weis, Nina

    2008-01-01

    In the present case series report we describe seven recent cases of typhoid fever. All the patients were travellers returning from Pakistan, where typhoid is endemic. Salmonella typhi isolated from the patients by blood culture were reported as intermediary susceptible to fluoroquinolones in six...

  7. Dyb venøs trombose - epidemiologi, diagnose og behandling

    DEFF Research Database (Denmark)

    Sejersen, Holger Marquard; Nielsen, Hans Kræmmer; Thyssen, Jacob Pontoppidan;

    2007-01-01

    and hormone therapy. DVT most often appears in the crural veins. The diagnosis is based on ultrasound, d-dimer and clinical examination. Correct treatment requires gradient compression hosiery, low-molecular heparins and anticoagulant therapy. Duration of treatment depends on the individual risk of recurrence....

  8. Udredning og behandling af osteoporose ved cancer mammae uden knoglemetastaser

    DEFF Research Database (Denmark)

    Eiken, Pia Agnete; Kristensen, Bent; Langdahl, Bente Lomholt;

    2011-01-01

    The prevention of cancer-treatment-induced bone loss due to chemotherapy and long-term adjuvant breast cancer therapy has a high priority. We present an algorithm for the prevention and treatment of osteoporosis during treatment of nonmetastatic breast cancer....

  9. Osteoporosens betydning for behandling af frakturer og ortopaediske muligheder

    DEFF Research Database (Denmark)

    Lauritzen, J B

    2001-01-01

    The treatment of osteoporosis-related fractures can be difficult, when secure fixation and stable osteosynthesis is obtained in frail trabecular and cortical bone. In the case of defects, bone grafting and substitutes may be needed to reinforce osteosynthesis and promote fracture healing, which may......, intramedullary nails with neck screw, retrograde intramedullary nails, external fixation, cannulated screws, various plates, tension band wiring, threaded K-pins, and to some extent arthroplasties and reconstructive spine instrumentation. The goal in the treatment of osteoporosis-related fractures is to restore...... be delayed. The structural grafts may be biologically inert or osteoconductive, but also osteoinductive, and various osteoinductive growth factors and hormones could be a supplement to treatment. Several types of osteosyntheses have improved the clinical outcome, among them: sliding hip screw, neck screws...

  10. Behov for bedre organisering af udredning og behandling af hoste

    DEFF Research Database (Denmark)

    Ulrik, Charlotte Suppli

    2013-01-01

    Cough is frequently a reason for seeing a doctor. Cough has a wide range of causes and the diagnosis can be difficult to make. Cough is often benign and self-limiting but can also be the first sign of malignancy. Especially chronic cough reduces the patients' quality of life. The purpose of this ......Cough is frequently a reason for seeing a doctor. Cough has a wide range of causes and the diagnosis can be difficult to make. Cough is often benign and self-limiting but can also be the first sign of malignancy. Especially chronic cough reduces the patients' quality of life. The purpose...

  11. HIV kan og skal behandles samtidig med tuberkulose

    DEFF Research Database (Denmark)

    von der Maase, Sarah; Gerstoft, Jan; Wejse, Christian

    2014-01-01

    The proper timing of antiretroviral therapy (ART) to HIV-patients co-infected with tuberculosis has been debated. We review three studies on this matter. One study found a significant reduced mortality for patients with CD4+ T-cell counts (CD4+) ≤ 200 per mm3 who received ART early, whereas...... the other two studies found this difference for patients with CD4+ HIV after the initiation of ART....

  12. Vellykket konservativ behandling af chylopericardium efter koronar bypassoperation

    DEFF Research Database (Denmark)

    Clausen, Jesper Holmbæck; Veien, Karsten Tange

    2012-01-01

    Chylopericardium after thoracic duct injury is a rare but serious complication of thoracic surgery with mortality rates above 50% without intervention. Complications of chylopericardium are malnutrition, immunosuppression, electrolyte derangement and tamponade. This case describes a 67-year...

  13. Medicinsk behandling af små abdominale aortaaneurismer

    DEFF Research Database (Denmark)

    Høgh, Annette Langager; Sandermann, Jes; Lindholt, Jes Sanddal

    2008-01-01

    Our expectation is that the numbers of diagnosed small abdominal aortic aneurysms (AAA) will increase in the future. Slowing down the progression of AAAs is of great interest as this could prevent cost-intensive and potential lethal operations. Recent studies indicate that modern medical treatment...

  14. Barn utsatt for komplekse traumer: diagnosebegrep og behandling

    OpenAIRE

    Rønning, Christina; Teige, Synnøve Oddfrid Veien; Løkke, Ragnhild Støren

    2009-01-01

    The purpose of this thesis was to consider whether complex trauma disorders should be included as a diagnostic entity, and to evaluate if trauma-focused cognitive behavioral therapy (TF-CBT) is a suitable treatment model for children with complex trauma reactions. First, we reviewed arguments supporting the existence of a complex trauma diagnosis, and considered research that supports postulated core problems in these children. Second, we presented research on the TF-CBT model for children ex...

  15. Dilemmaer i musikterapeutisk behandling af en traumatiseret flygtning med musikerbaggrund

    Directory of Open Access Journals (Sweden)

    Bolette Daniels Beck

    2016-12-01

    Full Text Available Denne artikel præsenterer et single case-studie af et receptivt musikterapiforløb med en 55-årig syrisk flygtning, som har været udsat for fængsling og tortur på grund af sine aktiviteter som protestsanger og musiker. Der beskrives problemstillinger og dilemmaer relateret til at anvende musik, der både kan trigge traumer, men også vække indre ressourcer. Kortlægning af patientens forskellige personlighedsdele og musikkens evne til integration af dem vil blive belyst gennem teorien om strukturel dissociation.

  16. Myopati hos en patient i behandling med simvastatin og fluconazol

    DEFF Research Database (Denmark)

    Pedersen, Jens Kristian; Lydolph, Magnus Christian; Somnier, Finn

    2016-01-01

    A 69-year-old female was admitted due to progressive loss of muscle strength following addition of fluconazole to long-term simvastatin treatment. Rhabdomyolysis was suspected and both drugs were discontinued. Forced diuresis was initiated together with a short course of prednisolone. After 21...

  17. Karkirurgisk behandling hos patienter med påvirket nyrefunktion

    DEFF Research Database (Denmark)

    Hensler, M K; Forrest, M; Lorentzen, Jørgen Ewald

    1994-01-01

    and blood pressure status was evaluated preoperatively and at follow-up. The perioperative mortality was 5% (n = 2) and morbidity 21% (n = 9). At discharge from hospital renal function was maintained in 38 patients (90%), including three patients who at the time of operation were without diuresis and had...

  18. Valg af behandling af akut, purulent divertikulitis er uafklaret

    DEFF Research Database (Denmark)

    Hupfeld, Line; Burcharth, Jakob; Pommergaard, Hans-Christian;

    2015-01-01

    Inflammation in colonic diverticula can develop into acute diverticulitis. Treatment varies depending on illness severity. Perforated diverticulitis with faecal peritonitis is treated surgically and Hartmann's procedure is the preferred operation. Peritoneal lavage might be an alternative...

  19. Intranasal glukagon til behandling af hypoglykaemi. En fremtidig behandlingsmulighed

    DEFF Research Database (Denmark)

    Carstens, S; Andersen, I; Gustafsson, Ida

    1994-01-01

    or glucose administered intravenously by a physician. These are however not optimal treatments. Obtaining intravenous access requires a medical doctor and glucagon injection is not always properly done by family members. Glucagon administered intranasally has been proven to raise blood glucose levels...... in volunteers. The effect of intranasal glucagon on blood glucose is similar to that seen after intramuscular administration for the first 15 minutes following administration. However, intranasal glucagon seems more physiological in that is stabilizes blood glucose concentrations at nearfasting levels, whereas...... glucagon given intramuscularly tends to give hyperglycaemia. Intranasal glucagon is easy to administer, and can thus prevent serious hypoglycaemic crises and thereby make diabetics and their families more secure....

  20. Non-invasiv behandling af slid og erosion

    DEFF Research Database (Denmark)

    Pallesen, Ulla; van Dijken, Jan WV

    2011-01-01

    Slid og erosion af tænder synes i dag at være et voksende problem for mange patienter. I de fleste tilfælde kan tandlægens tidlige diagnostik føre til, at forebyggende tiltag iværksættes i tide, så fortsatte skader ophører eller progressionen begrænses. Desværre er det ikke altid muligt og hvis s...

  1. Udredning og behandling af osteoporose ved cancer mammae uden knoglemetastaser

    DEFF Research Database (Denmark)

    Eiken, Pia A; Hansen, Mogens; Kristensen, Bent;

    2011-01-01

    The prevention of cancer-treatment-induced bone loss due to chemotherapy and long-term adjuvant breast cancer therapy has a high priority. We present an algorithm for the prevention and treatment of osteoporosis during treatment of nonmetastatic breast cancer.......The prevention of cancer-treatment-induced bone loss due to chemotherapy and long-term adjuvant breast cancer therapy has a high priority. We present an algorithm for the prevention and treatment of osteoporosis during treatment of nonmetastatic breast cancer....

  2. Behandling af epilepsi ved stimulation af nervus vagus

    DEFF Research Database (Denmark)

    Hansen, Christian Pilebaek; Sidenius, Per Christian; Gyllenborg, Jesper

    2010-01-01

    epilepsy surgery is not feasible, vagus nerve stimulation (VNS) should be offered. VNS seems to have an effect in all epilepsy syndromes and seizure types. VNS is generally well-tolerated, and may even improve mood and quality of life. Many more epilepsy patients in Denmark should be offered VNS....

  3. Narrativ og evidensbaseret behandling af komplekst traumatiserede mennesker

    DEFF Research Database (Denmark)

    Riber, Karin; Lindvig, Ditte

    2011-01-01

    Many survivors of potentially traumatizing events develop serious psychological problems. This article aims to critically examine two fundamentally different treatment paradigms. The article presents and discusses Michael White's narrative therapy, Metin Basoglu's modified behaviour therapy...... and Frank Neuners narrative exposure therapy in the hope that a resource focused exchange between these different theoretical and practical fields can enrich the psychological treatment of complex traumatized individuals. By comparing the respective perspectives, they are brought into a dialogue...... that results in building a bridge between narrative and evidence based theories and their practices....

  4. Kirurgisk behandling af anale fistler ved Crohns sygdom

    DEFF Research Database (Denmark)

    Heyckendorff-Diebold, Tina; Maeda, Yasuko; Buntzen, Steen;

    2012-01-01

    The treatment of transsphincteric anal fistulas in Crohn's disease is a balance between the elimination of the sepsis and the functional outcome. Loose setons can be used as a preoperative drainage or chronic treatment. Fibrin glue and the anal fistula plug are methods with excellent functional...... outcomes, but the success rate varies. The endorectal advancement flap is considered to be the gold standard. Ligation of the intersphincteric fistula tract is promising. Proctectomy or proctocolectomy in combination with transposition flaps may be necessary. A success rate of 66-70% has been reported....

  5. Pancreastraumer hos børn--operativ versus nonoperativ behandling

    DEFF Research Database (Denmark)

    Haugaard, Michael Valentin; Penninga, Luit; Ifaoui, Inge Bøtker-Rasmussen;

    2012-01-01

    Pancreatic trauma is more frequent in children than in adults and is often caused by trauma to the upper part of the abdomen. Mortality is low, but morbidity is high. Pancreatic trauma can be treated operatively or non-operatively, but there is disagreement about the optimal treatment strategy...

  6. Transanal minimally invasive surgery til behandling af lav rectumcancer

    DEFF Research Database (Denmark)

    Levic, Katarina; Bulut, Orhan

    2014-01-01

    Laparoscopic total mesorectal excision (LTME) has become the standard surgical treatment of rectal cancer. There is however technical challenges when operating patients with a narrow pelvis with tumours located in distal or middle part of the rectum. We describe a case of a 71-year-old male...

  7. Transanal minimal invasiv kirurgi til behandling af lav rectumcancer

    DEFF Research Database (Denmark)

    Levic, Katarina; Bulut, Orhan

    2014-01-01

    Laparoscopic total mesorectal excision (LTME) has become the standard surgical treatment of rectal cancer. There is however technical challenges when operating patients with a narrow pelvis with tumours located in distal or middle part of the rectum. We describe a case of a 71-year-old male...

  8. Behandling af patienter med Guillan Barré syndrom

    DEFF Research Database (Denmark)

    Oliel, Vibeke S.

    2011-01-01

    Resumè Guillain Barrés syndrom er en autoimmum sygdom karakteriseret ved motorisk, sensorisk og autonom dysfunktion. I Danmark rammes omkring 80 personer i alle aldre årligt af sygdommen. Akut inflammatorisk polyradikoloneuropati rammer de perifere nervers nerveskeder og medfører progredierende...

  9. Fotodynamisk behandling af kolangiokarcinom hos 80-årig

    DEFF Research Database (Denmark)

    Ulstrup, Thomas; Pedersen, Finn Møller

    2013-01-01

    70% of cholangiocarcinomas (CC) are perihilar lesions. At the time of diagnosis few are candidates for complete resection, and the standard palliative therapy has been biliary stenting. Studies have shown that photodynamic therapy (PDT) improves survival time. In this case report we describe an 8...

  10. Rituximab (MabThera) til behandling af aktiv reumatoid artritis

    DEFF Research Database (Denmark)

    El Fassi, Daniel; Nielsen, Claus Henrik; Bendtzen, Klaus

    2006-01-01

    Rituximab (RTX) is a murine/human monoclonal antibody to CD20, a protein expressed almost exclusively on human B-lymphocytes. RTX induces rapid and marked B-cell depletion with beneficial clinical effects in 1/3 to 1/2 of rheumatoid arthritis patients. Treatment is given as two iv. infusions...... with a two-week interval and in combination with methotrexate. Mild to moderate side-effects are frequent, particularly during the first infusion, but long-term side-effects are generally rare, although pulmonary events and reactivation of viral infections of the liver is of concern....

  11. Årsager, udredning og behandling af abortus habitualis

    DEFF Research Database (Denmark)

    Larsen, Elisabeth Clare; Christiansen, Ole Bjarne

    2012-01-01

    Recurrent miscarriage (RM) is defined as three or more consecutive early pregnancy losses and affects 1% of couples. RM is probably a multifactorial disease and evaluation includes parental karyotyping, testing for uterine anomalies, thyroid dysfunction, thrombophilia and immune factors. Couples...

  12. Rituximab (MabThera) til behandling af aktiv reumatoid artritis

    DEFF Research Database (Denmark)

    Fassi, Daniel El; Nielsen, Claus Henrik; Bendtzen, Klaus

    2006-01-01

    Rituximab (RTX) is a murine/human monoclonal antibody to CD20, a protein expressed almost exclusively on human B-lymphocytes. RTX induces rapid and marked B-cell depletion with beneficial clinical effects in 1/3 to 1/2 of rheumatoid arthritis patients. Treatment is given as two iv. infusions with...

  13. Karakteristik, diagnostik og behandling af patienter med autoimmun hepatitis

    DEFF Research Database (Denmark)

    Ytting, Henriette; Larsen, Fin Stolze

    2012-01-01

    Autoimmune hepatitis is a relatively rare disease that may lead to rapidly progressing liver cirrhosis and even fulminant liver failure, if diagnosis and treatment is delayed or ineffective. Diagnosing the disease can be challenging, and one in five patients respond insufficiently to standard tre...... treatment. Patients, who are diagnosed late in the disease course or only respond partly to medical treatment, are at high risk of developing severe liver insufficiency. This article summarizes the present knowledge and evidence regarding diagnostics, therapy and disease course....

  14. Muskuloskeletal behandling af 11-årig med artrogrypose

    DEFF Research Database (Denmark)

    Thomsen, Maria Morandi; Thomsen, Stig Aaberg; Due, Pernille

    2010-01-01

    A two-year-old patient was diagnosed with arthrogryposis because of inflected knees (15-20 degrees) and stiff hamstrings. All joints and reflexes were normal. Activities were described as age-appropriate, but the patient walked with inflected knees and increased lumbal lordosis. Physiotherapy...... and botox did not improve the condition. Because of pain and hampered activities, the patient - now aged 11 years - was treated with musculoskeletal medicine. After treatment the patient could walk normally without pain and stand with stretched knees....

  15. Private personers behandling af fortrolige oplysninger fra offentlige myndigheder

    DEFF Research Database (Denmark)

    Bønsing, Sten

    2014-01-01

    Denne artikel undersøger, i hvilket omfang den private borger, der kommer i besiddelse af fortrolige oplysninger fra forvaltningsmyndigheder, er begrænset i anvendelsen og videregivelsen heraf. Der gælder ikke et samlet regelsæt, der afgør spørgsmålet, men en række regler i straffeloven og person...... persondataloven kan bringes i anvendelse. Samlet set vil der ofte gælde en form for tavshedspligt for den private, men den endelige konklusion afhænger af de konkrete oplysningers karakter, og hvordan oplysningerne håndteres af borgeren....

  16. Endovenøs termisk behandling af varicer i underekstremiteterne

    DEFF Research Database (Denmark)

    Bækgaard, Niels; Schroeder, Torben V

    2011-01-01

    Using a systematic review process, we identified 15 randomised controlled trials comparing either of the two endovenous thermal techniques, radiofrequency or laser ablation, with conventional open surgery for great saphenous varicose veins. The majority of trials were small and had short-term fol...

  17. Behandling af mani hos voksne (Treatment of mania in adults)

    DEFF Research Database (Denmark)

    Licht, Rasmus Wentzer; Straszek, Sune Puggaard Vogt

    2014-01-01

    Around 1% of the population will experience at least one episode of mania. Mania has negative social consequences, may lead to cognitive impairment and may even be lethal. Therefore, prompt and efficient medical action needs to be taken, not only addressing the acute symptoms but also the high ri...... of recurrence. Many well-documented antimanic drugs are at hand, and the database has been carefully outlined in recent guidelines, also addressing factors of importance in choosing among the options. The real challenge is dealing with non-response, where the database is extremely poor....

  18. Trombosering af mekanisk mitralklapprotese under behandling med dabigatran

    DEFF Research Database (Denmark)

    Thomsen, Jakob Hartvig; Kjaergaard, Jesper; Saust, Laura Trolle;

    2014-01-01

    Dabigatran has been approved for prevention of thromboembolic complications in nonvalvular atrial fibrillation. We present a case of thrombosis of a mechanical prosthetic mitral valve during anticoagulation with dabigatran, switched from warfarin. The patient presented with cardiogenic shock...

  19. Laver vejplanlæggere ærligere prognoser end jernbaneplanlæggere?

    DEFF Research Database (Denmark)

    Næss, Petter; Flyvbjerg, Bent; Buhl, Søren L.

    2005-01-01

    Undersøgelser viser at der er betydelige afvigelser mellem forventede og faktiske mængder trafik. Specielt er afvigelserne store for jernbaneprojekter. Også for vejprojekter er prognoserne ofte forkerte, men her er trafikmængden ofte større end forventet modsat jerbaneprojekter, hvor den ofte er ...

  20. Dårlig prognose for rygsmerter når patienten er involveret i erstatningssager - sekundaerpublikation

    DEFF Research Database (Denmark)

    Rasmussen, Claus; Leboeuf-Yde, Charlotte; Hestbaek, Lise;

    2009-01-01

    for several prognostic factors. After one year the adjusted odds ratio for "no improvement" in patients making a claim was calculated to 4.2 for low-back patients and 17.4 for neck patients. The results indicate an association between financial claim and poor prognosis. Udgivelsesdato: 2009-May-4......Patients with back pain frequently file financial claims concerning causation and disability level. We examined if the financial claim could independently influence the prognosis or if such a tendency was instead caused by a more severe degree of disease. The associations were therefore adjusted...

  1. Targeting of Topoisomerase I for Prognoses and Therapeutics of Camptothecin-Resistant Ovarian Cancer

    Science.gov (United States)

    Tsai, Hsiang-Ping; An, Herng-Wei; Lee, Chi-Ming; Wu, Jen-Chine; Chen, Chien-Shu; Huang, Shih-Hao; Hwang, Jaulang; Cheng, Kur-Ta; Leiw, Phui-Ly; Chen, Chi-Long; Lin, Chun-Mao

    2015-01-01

    DNA topoisomerase I (TOP1) levels of several human neoplasms are higher than those of normal tissues. TOP1 inhibitors are widely used in treating conventional therapy-resistant ovarian cancers. However, patients may develop resistance to TOP1 inhibitors, hampering chemotherapy success. In this study, we examined the mechanisms associated with the development of camptothecin (CPT) resistance in ovarian cancers and identified evodiamine (EVO), a natural product with TOP1 inhibiting activity that overcomes the resistance. The correlations among TOP1 levels, cancer staging, and overall survival (OS) were analyzed. The effect of EVO on CPT-resistant ovarian cancer was evaluated in vitro and in vivo. TOP1 was associated with poor prognosis in ovarian cancers (p = 0.024). EVO induced apoptosis that was detected using flow cytometry and terminal deoxynucleotidyl transferase dUTP nick end labeling (TUNEL) assay. The tumor size decreased significantly in the EVO treatment group compared with the control group (p < 0.01) in a xenograft mouse model. Effects of drugs targeting TOP1 for prognosis and therapy in CPT-resistant ovarian cancer are anticipated. EVO with TOP1 can be developed as an antiproliferative agent for overcoming CPT resistance in ovarian cancers. PMID:26207989

  2. Targeting of Topoisomerase I for Prognoses and Therapeutics of Camptothecin-Resistant Ovarian Cancer.

    Directory of Open Access Journals (Sweden)

    Yu-Chieh Lee

    Full Text Available DNA topoisomerase I (TOP1 levels of several human neoplasms are higher than those of normal tissues. TOP1 inhibitors are widely used in treating conventional therapy-resistant ovarian cancers. However, patients may develop resistance to TOP1 inhibitors, hampering chemotherapy success. In this study, we examined the mechanisms associated with the development of camptothecin (CPT resistance in ovarian cancers and identified evodiamine (EVO, a natural product with TOP1 inhibiting activity that overcomes the resistance. The correlations among TOP1 levels, cancer staging, and overall survival (OS were analyzed. The effect of EVO on CPT-resistant ovarian cancer was evaluated in vitro and in vivo. TOP1 was associated with poor prognosis in ovarian cancers (p = 0.024. EVO induced apoptosis that was detected using flow cytometry and terminal deoxynucleotidyl transferase dUTP nick end labeling (TUNEL assay. The tumor size decreased significantly in the EVO treatment group compared with the control group (p < 0.01 in a xenograft mouse model. Effects of drugs targeting TOP1 for prognosis and therapy in CPT-resistant ovarian cancer are anticipated. EVO with TOP1 can be developed as an antiproliferative agent for overcoming CPT resistance in ovarian cancers.

  3. Aids-relaterede non-Hodgkin-lymfomer. Klinisk billede og prognose

    DEFF Research Database (Denmark)

    Penkowa, M; Hansen, P B

    1998-01-01

    to be a clear association between Epstein-Barr virus (EBV) and immunoblastic lymphomas (a subtype of large cell lymphomas) in AIDS patients. Patients with AIDS often have widespread disease at presentation and frequent involvement of extranodal sites (CNS, liver, bone marrow, the digestive tract and skin...... below 130 x 10(9)/l, widespread symptoms of disease, presence of EBV in the lymphoma and immunoblastic histology. Udgivelsesdato: 1998-Apr-27...

  4. Mg++-Stoffwechselkorrelationen als Diagnose und Prognose beim Sport und bei Hypertonikern

    Directory of Open Access Journals (Sweden)

    Porta S

    2012-01-01

    Full Text Available Anhand eines Vergleichs der Daten dreier verschiedener Untersuchungen konnten wir demonstrieren, dass Veränderungen von ionisiertem Magnesium im Blut sowohl mit metabolischen Veränderungen als auch mit diastolischen und systolischen Blutdruckveränderungen korrelieren. Zuerst gelang es darzulegen, dass man imstande ist, durch die Bestimmung von Mg++ zusammen mit pH, Laktat und Leistungspunkten bei einem sportlichen Wettbewerb schon vor dem Bewerb anhand einer Mg++/pH-Korrelation die Chancen für anschließendes erfolgreiches Abschneiden vorherzusagen [1, 2]. Untersuchungen dieser Werte nach dem Bewerb gestatteten durch korrelative Analysen von Mg++-Veränderungen, Leistungspunkten und Laktatveränderungen einen tieferen Einblick in das Anstrengungs- Erfolgs-Verhältnis der Teilnehmer. Ähnlich den Resultaten beim Sport konnten durch Korrelation von Mg++ und diastolischem RR nach dem Test die signifikant-prognostischen Wirkungen der Mg++-Bestimmung gezeigt werden. Ähnlich wie beim Verhältnis zwischen Mg++ und Leistungspunkten zeigten auch hier diejenigen Patienten mit den geringsten Mg++-Abweichungen nach Provokation [1–3] auch die geringsten erregungsbedingten Veränderungen von diastolischem RR und Herzfrequenz durch den Test. Schließlich konnten wir bei 300 hypertonen Diabetikern zeigen, dass Blutzuckerveränderungen im Rahmen eines Glukoseprofils abhängig vom systolischen Blutdruck sind und eng mit Mg++-Veränderungen einhergehen, was einige neue Gedanken über den Mechanismus des Elektrolytverlusts bei Typ-2-Diabetikern und die Rolle des Blutdrucks bei Blutzuckerschwankungen zulässt [4–6].

  5. Mg++-Stoffwechselkorrelationen als Diagnose und Prognose beim Sport und bei Hypertonikern

    OpenAIRE

    2012-01-01

    Anhand eines Vergleichs der Daten dreier verschiedener Untersuchungen konnten wir demonstrieren, dass Veränderungen von ionisiertem Magnesium im Blut sowohl mit metabolischen Veränderungen als auch mit diastolischen und systolischen Blutdruckveränderungen korrelieren. Zuerst gelang es darzulegen, dass man imstande ist, durch die Bestimmung von Mg++ zusammen mit pH, Laktat und Leistungspunkten bei einem sportlichen Wettbewerb schon vor dem Bewerb anhand einer Mg++/pH-Korrelation di...

  6. Fulda thyroid nodule prognosis program; Das Fuldaer Schilddruesen-Knoten-Prognose-Programm

    Energy Technology Data Exchange (ETDEWEB)

    Koerber-Hafner, N.; Koerber, C. [Nuklearmedizinische Praxis Fulda, Fulda (Germany)

    2008-09-15

    The 'Fulda'-program calculates for thyroid nodule patients the probability of management with respect to surgery, follow up, radioiodine therapy or fine needle aspiration biopsy by use of the weighted factors: pre-existing results, patient age, palpation, thyroid volume, marginal nodule perfusion, echo texture, thyroid volume increase and TSH level. As the following definite management is in good correlation to the precalculated management, the 'Fulda'-program could be useful for organisation and strategy of thyroid nodule patients. (orig.)

  7. Cervical spine injury. Diagnosis, prognosis and management; Trauma der Halswirbelsaeule. Diagnose, Prognose und Management

    Energy Technology Data Exchange (ETDEWEB)

    Schueller-Weidekamm, C. [AKH, Medizinische Universitaet Wien (Austria). Abteilung fuer Neuroradiologie und Muskuloskelettale Radiologie

    2008-05-15

    Cervical spine injuries are a common occurrence in multi-trauma patients and should be taken into account when planning further clinical management. This review describes in detail upper and lower cervical spine injuries and introduces the sub-axial injury classification (SLIC) that is based on three components: injury morphology, integrity of the discoligamentous complex and the neurologic status of the patient. If the total SLIC score is <3, non-surgical treatment is recommended. If the total is {>=}5, operative treatment is indicated as such a score is associated with instability and probably neurologic deficits. The precise diagnosis of the radiologist, which would include the SLIC classification, should facilitate clinical decision-making about further management. (orig.) [German] Halswirbelsaeulenverletzungen sind bei polytraumatisierten Patienten haeufig und sollten beim klinischen Management des Patienten beruecksichtigt werden. Verletzungen der oberen Halswirbelsaeule werden als Sonderformen eingeteilt. Die subaxialen Verletzungen koennen nach der SLIC-Klassifikation ('sub-axial injury classification') gescort werden, die auf der Morphologie der Verletzung, dem diskoligamentaeren Komplex und dem neurologischen Status basiert. Bei einem Score <3 wird ein konservatives Management empfohlen. Bei einem Score {>=}5 sollte eine operative Versorgung der Halswirbelsaeule vorgenommen werden, da die Verletzung eine Instabilitaet und moeglicherweise auch ein neurologisches Defizit verursacht. Anhand einer praezisen Diagnose des Radiologen unter Beruecksichtigung der SLIC-Klassifikation sollte dem Kliniker die Entscheidung fuer das weitere Management erleichtert werden. (orig.)

  8. ECOLOGICAL AND GEOGRAPHICAL PRINCIPLES OF PROGNOSING THE MORBIDITY BY MALIGNANT NEOPLASMS OF POPULATION OF DAGHESTAN REPUBLIC

    Directory of Open Access Journals (Sweden)

    G. M. ABDURAKHMANOV

    2010-01-01

    Full Text Available The work is a complex ecological and geographical research of natural and anthropogenic components in regions and towns of Daghestan republic for revealing the dependence between the state of environment and dynamics of morbidity. For the first time for the South Russia in Daghestan the complex ecological monitoring of malignant morbidities the important possibilities of its use for bioindication are shown.

  9. Experience of prognosing of basic anthropometric indices in children at birth

    Directory of Open Access Journals (Sweden)

    Pochatkov V.A.

    2012-06-01

    Full Text Available The fetus of a man develops in difficult conditions of mutual relations, both with an organism of mother, and with environment, and consequently protection and strengthening of health of children should be carried out taking into account health of mother, the way of life, place of living, course of pregnancy and delivery. The research goal is to reveal the factors which are predictors of physical development of newborn children and drawing up of prognostic models of anthropometric indicators at birth. Materials and methods: Survey of 220 newborns born in time and their mothers has been conducted. The anthropometry has included measurement of body weight, length, head and breast circles in children at birth. Results: The analysis of somatic, infectious, obstetric and gynecologic incidence of mothers of studied children, and also the course of pregnancy and delivery has been carried out. Conclusion: According to the data physical development of newborn children has been influenced by a number of factors. During the research work the prognostic models have been determined allowing to define the factors influencing physical intrauterine development of a child.

  10. Akut myokardieinfarkt i Danmark. Udvikling i incidens og prognose gennem 20 år

    DEFF Research Database (Denmark)

    Madsen, Mette; Rasmussen, S; Juel, K

    2000-01-01

    INTRODUCTION: The paper describes the epidemiology of acute myocardial infarction in Denmark. The study provides statistics on mortality, incidence and case-fatality for 1996 and the time trend since 1978. The results are compared to the results from the international MONICA study. METHOD...... fatality. In the period 1985-1996 the incidence decreased by 3.5% per year for men and 2.5% for women. Mortality rates within 28 days after admission to hospital with MI was almost constant until 1988 following which there was a significant drop. Despite the improved prognosis for MI patients, one quarter...

  11. Feed-in prognoses for renewable forms of energy; Einspeiseprognosen fuer neue erneuerbare Energien - Schlussbericht

    Energy Technology Data Exchange (ETDEWEB)

    Dierer, S.; Remund, J.; Cattin, R. [METEOTEST, Berne (Switzerland); Koller, T.; Strasser, P. [enersis suisse, Berne (Switzerland)

    2010-02-15

    This report for the Swiss Federal Office of Energy (SFOE) aims at determining the potential of improved feed-in forecasts for new renewable energies (NRE) in Switzerland. The characteristics of the Swiss energy market are considered. Benefits of and potential for improvement are identified and recommendations for additional measures to be taken are given. The authors note that at present the forecast systems for wind energy are quite sophisticated, while there is room for improvement for solar energy and micro hydro unit forecasts. Ways of improving the forecasts are discussed. The business case developed within the framework of this project is to be completed and quantified as soon as data for 2009 is provided by the regulatory body 'swissgrid' and the balance group for renewable energies. The report is completed with recommendations for further work.

  12. Seismo-acoustic forecasting of gas-dynamic phenomena; Seismoakustische Prognose gasdynamischer Erscheinungen

    Energy Technology Data Exchange (ETDEWEB)

    Kurfuerst, W.; Mayhofer, K.; Reuter, M.; Scheerer, H.J.; Veksler, J. [Marco Systemanalyse und Entwicklung GmbH, Dachau (Germany)

    2005-06-01

    The paper presents a method for the seismo-acoustic forecasting of sudden coal and gas outbursts when driving roadways at the Karaganda collieries in Kazakhstan. The process is based on the recording and analysis of seismo-acoustic pulses, which are detected after coal-seam excitation by the cutting head of the roadheading machine. Describes the discrimination parameters for seismic signals obtained in hazardous and non-hazardous situations (shift to lower frequencies, increase in intensity). Structure-borne noise sensors from Marco GmbH were successfully trialled at Karaganda. The techniques being used and the criteria obtained for seismo-acoustic forecasting make it possible to monitor the chronological development of the fracturing and fissuration process and from this to obtain information on the development of a focal point for disturbances that can lead to hazardous incidents. The authors believe that there is real potential in taking the results acquired to date and combining them with the now much improved pit-worthy computer technology in order to develop an automatic forecasting system. (orig.)

  13. Low serum interleukin-13 levels correlate with poorer prognoses for colorectal cancer patients.

    Science.gov (United States)

    Saigusa, Susumu; Tanaka, Koji; Inoue, Yasuhiro; Toiyama, Yuji; Okugawa, Yoshinaga; Iwata, Takashi; Mohri, Yasuhiko; Kusunoki, Masato

    2014-01-01

    Interleukin-13 (IL-13) is an immunosuppressive cytokine produced by several immune cells and cancer cells. The aim of this retrospective study was to determine if serum IL-13 levels have an association with clinical outcome in patients with colorectal cancer. A total of 241 patients with colorectal cancer were enrolled in the present study. Preoperative serum IL-13 concentrations were measured by enzyme-linked immunosorbent assay. We analyzed the association of serum IL-13 levels with clinicopathological variables. Patients with lymph node metastasis, lymphatic invasion, vascular invasion, distant metastases or advanced stage of disease had significantly lower serum IL-13 levels. Low serum IL-13 was significantly associated with both poor recurrence-free and overall survival. Multivariate analysis showed that low IL-13 levels were an independent predictive marker for poor prognosis. In conclusion, our data suggest that low serum IL-13 levels may be a useful predictive marker for poor prognosis in colorectal cancer.

  14. The influence of climate changes on carbon cycle in the russian forests. Data inventory and long-scale model prognoses

    Energy Technology Data Exchange (ETDEWEB)

    Kokorin, A.O.; Nazarov, I.M.; Lelakin, A.L. [Inst. Global Climate and Ecology, Moscow (Russian Federation)

    1995-12-31

    The growing up climate changes arise the question about reaction of forests. Forests cover 770 Mha in Russia and are giant carbon reservoir. Climate changes cause disbalance in carbon budget that give additional CO{sub 2} exchange between forests and the atmosphere. The aim of the work is estimation of these fluxes. This problem is directly connected with an GHG inventory, vulnerability and mitigation assessment, which are necessary for future Russian Reports to UN FCCC. The work includes the following steps: (1) Collection of literature data as well as processing of the experimental data on influence of climate changes on forests, (2) Calculation of carbon budget as base for calculations of CO{sub 2} fluxes, (3) Developing of new version of CCBF (Carbon and Climate in Boreal Forests) model, (4) Model estimations of current and future CO{sub 2} fluxes caused by climate changes, forest cuttings, fires and reforestation

  15. Reliability of the thyroid stimulating hormone receptor antibodies level determination in diagnosing and prognosing of immunogenic hyperthyroidism

    Directory of Open Access Journals (Sweden)

    Aleksić Aleksandar Z.

    2009-01-01

    Full Text Available Background/Aim. Graves disease (GD is defined as hyperthyroidism with diffuse goiter caused by immunogenic disturbances. Antibodies to the thyroid stimulating hormone (TSH receptors of thyroid gland (TRAb have crucial pathogenetic importance in the development and maintenance of autoimmune hyperthyroidism. The aim of this study was to identify sensitivity, specificity, positive an negative predictive value of TRAb level in sera of patients with GD as well as to estimate significance of TRAb level for remission and GD relapses occurrence. Methods. We studied prospectively and partly retrospectively 149 patients, 109 female and 40 male patients, 5-78 years old, in the period 1982-2007. There were 96 patients with GD. The control group consisted of 53 patients, 21 with hyperthyroidism of second etiology and 32 patients on amiodarone therapy, with or without thyroid dysfunction TRAb was measured by radioreceptor assay (TRAK Assay and DYNO Test TRAK Human Brahms Diagnostica GMBH. Results. According to the results the sensitivity (Sn of TRAb test was 80%, specificity (Sp 100%, positive predictive value (PP 100% and negative predictive value (NP 83%. Also, the Sn of hTRAb test was 94%, Sp 100%, PP 100% and NP 94%. Our results show that an increased level of TRAb/hTRAb at the beginning of the disease and the level at the end of medical therapy is associated with an increased number of GD relapses and a shorter remission duration. Conclusion. Detection and measurement of TRAb in serum is a very sensitive method for diagnosing GD and very highly specific in vitro method for differential diagnosis of various forms of hyperthyroidism. Clinical significance of differentiating various forms of hyperthyroidism, using this in vitro assay, lays in adequate therapeutic choice for these entities.

  16. Medfødt hydrocephalus--forekomst og prognose. Mortalitet og morbiditet i en populationsbaseret opgørelse

    DEFF Research Database (Denmark)

    Christensen, Jacob Haaber; Hansen, Lars Kjaersgård; Garne, Ester

    2003-01-01

    The aim was to describe the prevalence and to estimate the prognosis of congenital hydrocephalus (HC) in fetuses and children.......The aim was to describe the prevalence and to estimate the prognosis of congenital hydrocephalus (HC) in fetuses and children....

  17. Impact of treatment time-related factors on prognoses and radiation proctitis after definitive chemoradiotherapy for cervical cancer.

    Science.gov (United States)

    Huang, Eng-Yen; Lin, Hao; Wang, Chong-Jong; Chanchien, Chan-Chao; Ou, Yu-Che

    2016-09-01

    This study aimed to investigate the impact of treatment time-related factors on outcomes and radiation proctitis in patients undergoing concurrent chemoradiotherapy (CCRT) for cervical cancer. From September 2001 to December 2012, 146 patients with stage IIB cervical squamous cell carcinoma treated with CCRT were reviewed from a prospective cohort. Patients who received the same dose (45 Gy) of external beam radiation therapy (EBRT) were included in the analysis (n = 125). The same equivalent dose of 2 Gy (EQD2) of high-dose-rate intracavitary brachytherapy (HDR-ICBT) was delivered at either 4 fractions of 6 Gy or 6 fractions of 4.5 Gy. The effects of the overall treatment time (OTT) and interval between EBRT and HDR-ICBT on the cancer-specific survival (CSS), local recurrence (LR), and incidence of proctitis were compared. The treatment time-related factors did not adversely affect the CSS and LR rates. The multivariate analyses did not identify the OTT as an independent factor of CSS (P = 0.839) and LR (P = 0.856). However, OTT ≤56 days (P = 0.026) was identified as the only independent factor of overall proctitis. The 5-year Grade 2 or greater proctitis rates were 14.9% and 0% (P = 0.001) in patients with the EBRT to ICBT interval ≤5 days and >5 days, respectively. To reduce rectal damage without compromising prognosis, the gap between EBRT and HDR-ICBT should exceed 5 days in cervical cancer patients undergoing CCRT. Strictly limiting the OTT to 56 days may result in radiation proctitis without improvements in prognosis.

  18. Comparison of BISAP, Ranson, MCTSI, and APACHE II in Predicting Severity and Prognoses of Hyperlipidemic Acute Pancreatitis in Chinese Patients

    Directory of Open Access Journals (Sweden)

    Lixin Yang

    2016-01-01

    Full Text Available In recent years, with the developing of living standard, hyperlipidemia becomes the second major reason of acute pancreatitis. It is important to predict the severity and prognosis at early stage of hyperlipidemic acute pancreatitis (HLAP. We compared the BISAP, Ranson, MCTSI, and APACHE II scoring system in predicting MSAP and SAP, local complications, and mortality of HLAP. A total of 326 diagnosed hyperlipidemic acute pancreatitis patients from August 2006 to July 2015 were studied retrospectively. Our result showed that all four scoring systems can be used to predict the severity, local complications, and mortality of HLAP. Ranson did not have significant advantage in predicting severity and prognosis of HLAP compared to other three scoring systems. APACHE II was the best in predicting severity of HLAP, but it had shortcoming in predicting local complications. MCTSI had outstanding performance in predicting local complications, but it was poor in predicting severity and mortality. BISAP score had high accuracy in assessment of severity, local complications, and mortality of HLAP, but the accuracy still needs to be improved in the future.

  19. Comparison of BISAP, Ranson, MCTSI, and APACHE II in Predicting Severity and Prognoses of Hyperlipidemic Acute Pancreatitis in Chinese Patients.

    Science.gov (United States)

    Yang, Lixin; Liu, Jing; Xing, Yun; Du, Lichuan; Chen, Jing; Liu, Xin; Hao, Jianyu

    2016-01-01

    In recent years, with the developing of living standard, hyperlipidemia becomes the second major reason of acute pancreatitis. It is important to predict the severity and prognosis at early stage of hyperlipidemic acute pancreatitis (HLAP). We compared the BISAP, Ranson, MCTSI, and APACHE II scoring system in predicting MSAP and SAP, local complications, and mortality of HLAP. A total of 326 diagnosed hyperlipidemic acute pancreatitis patients from August 2006 to July 2015 were studied retrospectively. Our result showed that all four scoring systems can be used to predict the severity, local complications, and mortality of HLAP. Ranson did not have significant advantage in predicting severity and prognosis of HLAP compared to other three scoring systems. APACHE II was the best in predicting severity of HLAP, but it had shortcoming in predicting local complications. MCTSI had outstanding performance in predicting local complications, but it was poor in predicting severity and mortality. BISAP score had high accuracy in assessment of severity, local complications, and mortality of HLAP, but the accuracy still needs to be improved in the future.

  20. Comparison of Existing Clinical Scoring Systems in Predicting Severity and Prognoses of Hyperlipidemic Acute Pancreatitis in Chinese Patients

    OpenAIRE

    Qiu, Lei; Sun, Rui Qing; Jia, Rong Rong; Ma, Xiu Ying; Cheng, Li; Tang, Mao Chun; Zhao, Yan

    2015-01-01

    Abstract It is important to identify the severity of acute pancreatitis (AP) in the early course of the disease. Clinical scoring systems may be helpful to predict the prognosis of patients with early AP; however, few analysts have forecast the accuracy of scoring systems for the prognosis in hyperlipidemic acute pancreatitis (HLAP). The purpose of this study was to summarize the clinical characteristics of HLAP and compare the accuracy of conventional scoring systems in predicting the progno...

  1. Comparison of BISAP, Ranson, MCTSI, and APACHE II in Predicting Severity and Prognoses of Hyperlipidemic Acute Pancreatitis in Chinese Patients

    OpenAIRE

    Lixin Yang; Jing Liu; Yun Xing; Lichuan Du; Jing Chen; Xin Liu; Jianyu Hao

    2016-01-01

    In recent years, with the developing of living standard, hyperlipidemia becomes the second major reason of acute pancreatitis. It is important to predict the severity and prognosis at early stage of hyperlipidemic acute pancreatitis (HLAP). We compared the BISAP, Ranson, MCTSI, and APACHE II scoring system in predicting MSAP and SAP, local complications, and mortality of HLAP. A total of 326 diagnosed hyperlipidemic acute pancreatitis patients from August 2006 to July 2015 were studied retros...

  2. Comparison of Existing Clinical Scoring Systems in Predicting Severity and Prognoses of Hyperlipidemic Acute Pancreatitis in Chinese Patients

    Science.gov (United States)

    Qiu, Lei; Sun, Rui Qing; Jia, Rong Rong; Ma, Xiu Ying; Cheng, Li; Tang, Mao Chun; Zhao, Yan

    2015-01-01

    Abstract It is important to identify the severity of acute pancreatitis (AP) in the early course of the disease. Clinical scoring systems may be helpful to predict the prognosis of patients with early AP; however, few analysts have forecast the accuracy of scoring systems for the prognosis in hyperlipidemic acute pancreatitis (HLAP). The purpose of this study was to summarize the clinical characteristics of HLAP and compare the accuracy of conventional scoring systems in predicting the prognosis of HLAP. This study retrospectively analyzed all consecutively diagnosed AP patients between September 2008 and March 2014. We compared the clinical characteristics between HLAP and nonhyperlipidemic acute pancreatitis. The bedside index for severity of acute pancreatitis (BISAP), Ranson, computed tomography severity index (CTSI), and systemic inflammatory response syndrome (SIRS) scores were applied within 48 hours following admission. Of 909 AP patients, 129 (14.2%) had HLAP, 20 were classified as severe acute pancreatitis (SAP), 8 had pseudocysts, 9 had pancreatic necrosis, 30 had pleural effusions, 33 had SIRS, 14 had persistent organ failure, and there was 1 death. Among the HLAP patients, the area under curves for BISAP, Ranson, SIRS, and CTSI in predicting SAP were 0.905, 0.938, 0.812, and 0.834, 0.874, 0.726, 0.668, and 0.848 for local complications, and 0.904, 0.917, 0.758, and 0.849 for organ failure, respectively. HLAP patients were characterized by younger age at onset, higher recurrence rate, and being more prone to pancreatic necrosis, organ failure, and SAP. BISAP, Ranson, SIRS, and CTSI all have accuracy in predicting the prognosis of HLAP patients, but each has different strengths and weaknesses. PMID:26061329

  3. Characteristics and prognoses of patients treated by an anaesthesiologist-manned prehospital emergency care unit. A retrospective cohort study

    DEFF Research Database (Denmark)

    Mikkelsen, Søren; Lossius, Hans Morten; Toft, Palle

    2017-01-01

    public health planning, we describe the workload of a prehospital anaesthesiologist-manned mobile emergency care unit (MECU) and the total population it services in terms of factors associated with mortality. PARTICIPANTS: The study is a register-based study investigating all missions carried out......OBJECTIVE: When planning and dimensioning an emergency medical system, knowledge of the population serviced is vital. The amount of literature concerning the prehospital population is sparse. In order to add to the current body of literature regarding prehospital treatment, thus aiding future....... PRIMARY AND SECONDARY OUTCOME MEASURES: Primary outcome measures were number of missions and number of patient contacts. Secondary patient variables were mortality and association between mortality and age, sex, comorbidity, prior admission to hospital and response time. RESULTS: The MECU completed 41 513...

  4. ELBE - Validation and improvement of load prognoses (project phase 1); ELBE - Validierung und Verbesserung von Lastprognosen (Projektphase 1)

    Energy Technology Data Exchange (ETDEWEB)

    Kronig, P.; Waelchli, U.; Zuercher, S. [BKW FMB Energie AG, Bern (Switzerland); Hoeckel, M. [Berner Fachhochschule, Biel (Switzerland)

    2009-10-15

    In the project 'Prognosekompetenz' we have identified and quantified by means of a comprehensive analysis of grid and climate data the factors which have a significant impact on the grid load. The study focused in the beginning on the regional data from a big electricity utility. In a second step, additional local data were also considered to better identify climatic and economic characteristics. We found a strong correlation between load, on the one hand, and outdoor temperature and economic activity, on the other hand. The influence of further factors is very limited. On this basis we developed two Matlab-based, easy-to-use tools for the prediction of the daily grid load profile in quarter-of-hour steps. One tool uses the method of the transfer function, where specific correlation factors account for the influential factors. The second tool based on the method of the artificial neuronal network, which had been tuned with data from several years to make sure that a high accuracy is obtained. We could show by self developed testing procedures that for both tools the precision in forecasting the daily load profile is very high. (authors)

  5. Evaluation of CD25-positive cells in relation to the subtypes and prognoses in various lymphoid tumours in dogs.

    Science.gov (United States)

    Mizutani, Noriyuki; Goto-Koshino, Yuko; Tsuboi, Masaya; Kagawa, Yumiko; Ohno, Koichi; Uchida, Kazuyuki; Tsujimoto, Hajime

    2016-05-01

    Interleukin-2 receptor alpha chain (CD25) expression has been reported in human lymphoid tumours and suggested to correlate with the prognosis. In this study, we detected CD25-positive cells in various types of lymphoid tumours in dogs. Immunohistochemical analyses of the tissues from diffuse large B-cell lymphoma (DLBCL) (n = 6), T-zone lymphoma (TZL) (n = 5), and follicular lymphoma (FL) (n = 2) revealed that cells strongly positive for CD25 were observed generally in accordance with lymphoma cell localization. CD25-positive cells were consistently detected in TZL and FL cases; however, the number of CD25-positive cells was variable among DLBCL cases. Furthermore, we evaluated the rate of CD25-positive cells by flow cytometric analysis in 29 dogs with lymphoid malignancies, including high-grade B-cell lymphoma (n = 17), TZL (n = 5), FL (n = 2), cutaneous lymphoma (n=2), and acute lymphoblastic leukaemia (ALL) (n = 3). CD25-positivity in the lymph node cells was significantly higher in dogs with high-grade B-cell lymphoma (mean ± SD, 49.6 ± 31.3%) or TZL (mean ± SD, 80.2 ± 10.0%) than that in healthy dogs (mean ± SD, 9.8 ± 2.8%). In prognostic analysis of 15 cases with high-grade B-cell lymphoma, the progression-free survival was significantly shorter in CD25-high group than that in CD25-low group. The results obtained in this study are useful for subtype differentiation and prognostic analysis of canine lymphomas and future development of molecular-targeted therapy directed at CD25.

  6. Isolated new onset 'atypical' optic neuritis in the NMO clinic: serum antibodies, prognoses and diagnoses at follow-up.

    Science.gov (United States)

    Piccolo, L; Woodhall, M; Tackley, G; Juryńczyk, M; Kong, Y; Domingos, J; Gore, R; Vincent, A; Waters, P; Leite, M I; Palace, J

    2016-02-01

    Severe, recurrent or bilateral optic neuritis (ON) often falls within the neuromyelitis optica spectrum disorders (NMOSD), but the diagnosis can be particularly challenging and has important treatment implications. We report the features, course and outcomes of patients presenting with atypical ON when isolated at onset. We retrospectively analyzed 69 sequential patients referred to a single UK NMO center with isolated ON at onset. Aquaporin-4 antibody (AQP4-Ab) assessment was performed in all patients and IgG1 myelin-oligodenrocyte glycoprotein (MOG-Ab) in AQP4-Ab(neg) patients. 37 AQP4-Ab positive (AQP4-Ab(pos)) and 32 AQP4-Ab negative (AQP4-Ab(neg)) patients (8 with MOG-Ab) were identified. The AQP4-Ab(neg) group included heterogeneous diagnoses: multiple sclerosis (MS), NMO, relapsing isolated ON (RION), monophasic isolated ON and relapsing acute disseminated encephalomyelitis (ADEM)-like syndromes. Compared to AQP4-Ab(neg) patients, AQP4-Ab(pos) patients had a worse residual visual outcome from first attack (median VFSS 4 vs. 0, p = 0.010) and at last assessment (median VFSS 5 versus 2, p = 0.005). However, AQP4-Ab(neg) patients with RION also had poor visual outcome. Up to 35% of AQP4-Ab(neg) patients developed a LETM and two developed low positivity for AQP4-Ab over time. Eight AQP4-Ab(neg) patients (25%) were MOG-Ab positive, covering a range of phenotypes excluding MS; the first ON attack was often bilateral and most had relapsing disease with a poor final visual outcome [VFSS 4, range (0-6)]. In conlcusion, AQP4-Ab positivity is confirmed as a predictor of poor visual outcome but AQP4-Ab(neg) RION also had a poor visual outcome. Of those without AQP4-Ab, 25% had MOG-Ab and another 25% developed MS; thus, MOG-Ab is associated with AQP4-Ab(neg) non-MS ON.

  7. Monitorering og komplikationer ved konservativ behandling af svær, akut pankreatitis

    DEFF Research Database (Denmark)

    Novovic, Srdan; Malmstrøm, Marie Louise; Andersen, Anders Møller

    2013-01-01

    Severe acute pancreatitis (SAP) is associated with a high morbidity and a mortality risk of up to 20%. Although much progress has occurred during the latest couple of years, there are still some major controversies on important issues such as monitoring, fluid therapy, antibiotic treatment...

  8. Udredning og behandling af osteoporose hos patienter med prostatacancer uden knoglemetastaser

    DEFF Research Database (Denmark)

    Eiken, Pia Agnete; Langdahl, Bente Lomholt; Eiken, Frederik L;

    2011-01-01

    The prevention of cancer treatment-induced bone loss in patients with prostate cancer due to gonadotropin-releasing hormone (GnRH)-agonist, GnRH-antagonist and orchidectomi therapy has a high priority. We present an algorithm for the prevention and treatment of osteoporosis during treatment of non...

  9. Behandling af placenta percreta kræver involvering af flere specialer

    DEFF Research Database (Denmark)

    Clausen, Caroline; Lönn, Lars; Albrechtsen, Charlotte Krebs;

    2011-01-01

    Placenta percreta is a rare life-threatening obstetrical condition, often resulting in severe haemorrhage and hysterectomy. The incidence seems to be increasing, probably secondary to the increase in caesarean section rates. We present a protocol for an elective multidisciplinary approach...

  10. Behandling af angste psykiatriske patienter med MusiCure - et pilotprojekt

    Directory of Open Access Journals (Sweden)

    Torben Egelund Sørensen

    2005-02-01

    Full Text Available I perioden 1.11.2003 til 1.3.2004 blev der på to åbne og en lukket sengeafdeling på psykiatrisk afdeling, Horsens sygehus, gennemført et pilotprojekt, med det formål at undersøge om brugen af speciel designet musik (MusiCure ville have en positiv effekt på angste og urolige patienter. 30 patienter fik MusiCurebehandling en eller flere gange, og af disse fik de 26 en positiv effekt af behandlingen: De blev beroliget; faldt til ro/i søvn. For en patient havde behandlingeningen effekt, og for 3 patienter havde behandlingen en negativ effekt. Interviews med patienter og plejepersonalet viste at brugen af MusiCure havde en angstdæmpende effekt, enten givet aleneeller i kombination med PN medicin og /eller kugledyne. Det konkluderes at undersøgelsens samlede resultat tyder på at MusiCure kan anvendes til såvel psykotiske som ikke-psykotiskepatienter, og at MusiCure, anvendt alene eller sammen med kugledyne, kan være et alternativ til brugen af PN medicin. Artiklen er en revideret udgave af artikel med samme titel bragt på Musica Humanas hjemmeside.

  11. Behandling af blødende øsofagusvaricer med selvekspanderende metalstenter

    DEFF Research Database (Denmark)

    Dahlerup, Jens F; Kruse, Aksel; Grønbaek, Henning;

    2007-01-01

    We report that haemostasis was obtained by the use of SEMS in two patients with bleeding oesophageal varices which failed conventional therapy (vasoactive drugs, antibiotics, endoscopy, and Sengstaken balloon tamponade). One patient subsequently died of sepsis; the other was treated with TIPS...

  12. Endokrinologisk udredning, behandling og opfølgning af polycystisk ovariesyndrom

    DEFF Research Database (Denmark)

    Glintborg, Dorte; Rungby, Jørgen; Eskildsen, Peter;

    2010-01-01

    Polycystic ovary syndrome (PCOS) has a prevalence of 5-10% and is defined as oligomenorrhoea, hyperandrogenaemia and/or polycystic ovaries and the exclusion of other aetiologies for the patient's symptoms. There is currently no agreement on the initial evaluation programme for women referred...... with PCOS or on how the syndrome should be treated. Women with PCOS have an increased risk of the metabolic syndrome upon diagnosis and increased long-term risk of type 2 diabetes, cardiovascular disease and endometrial cancer. In the present overview, we give recommendations for relevant follow......-up examination of patients with PCOS based on a search of the available literature. Udgivelsesdato: 2010-Jan-18...

  13. Behandling og håndtering af kongenitte melanocytære naevi

    DEFF Research Database (Denmark)

    Bahn, Kamille-Amalie; Hædersdal, Merete; Schmidt, Grethe

    2016-01-01

    Congenital melanocytic naevi (CMN) appear in approximately 2.6% of Caucasians. There is a major demand for treatment but no vital indication. Laser therapy, curettage and excision are available treatment modalities, but there is no ideal treatment with documented long-term effect and without side...

  14. Behandling med valproat under graviditet: beskrivelse af fire cases med føtalt valproatsyndrom

    DEFF Research Database (Denmark)

    Sabers, Anne; Larsen, Katja; Blichfeldt, Susanne;

    2009-01-01

    INTRODUCTION: Treatment with valproate is associated with an increased risk of teratogenicity compared to other antiepileptic drugs and can cause a complex of serious symptoms usually referred to as "foetal valproate symdrome" which is characterised by major and minor malformations in association...

  15. Rapid eye movement sleep behavior disorder--diagnostik, årsager og behandling

    DEFF Research Database (Denmark)

    Zoetmulder, Marielle; Jennum, Poul Jørgen

    2009-01-01

    Rapid eye movement (REM) sleep behaviour disorder (RBD) is characterized by loss of REM sleep and related electromyographic atonia with marked muscular activity and dream enactment behaviour. RBD is seen in 0.5% of the population. It occurs in an idiopathic form and secondarily to medical...... and neurological disease. RBD is related to brainstem pathology. Furthermore, it is increasingly recognized that RBD is frequently related to Parkinsonian disorders and narcolepsy. This article reviews recent knowledge about RBD with focus on the diagnostic process and management....

  16. Behandling med dopaminagonister og udvikling af hjerteklapsygdom hos patienter med hyperprolaktinæmi

    DEFF Research Database (Denmark)

    Steffensen, Maria Charlotte; Mægbæk, Merete Lund; Laurberg, Peter

    2014-01-01

    Treatment with dopamin agonists, particularly cabergoline, is the primary and preferred therapy for prolactinomas and symptomatic hyperprolactinaemia due to its effectiveness and tolerability. However, an association has been demonstrated between fibrotic heart valve disease and high-dose dopamin...

  17. Acquisition and management of energy data. Opsamling og behandling af energi-data

    Energy Technology Data Exchange (ETDEWEB)

    Meyer, K.E.

    1989-07-15

    Three computer programmes have been developed for the collection and management of measurement data in connection with a small dual-purpose power plant in a rural area. One of these is a modem program which enables readings of operational measurements to be taken and transferred over a geographical distance. Another program generates a daily report on the system's operation in a way which is determined by the user. An independent copying program is an extension of the graphic program which makes it possible to copy parts of data files over shorter periods of time and through individual data channels. Measuring data can form the basis of a control system. These types of program are presented in detail. (AB).

  18. Et Patientperspektivistisk Studie i Brug af Alternativ Behandling hos Danske Patienter med Diabetes

    DEFF Research Database (Denmark)

    Gerbild, Helle Nygaard

    2008-01-01

    theory. The data originate from an explorative study based on semi-structured individual in-depth interviews with ten diabetic using CAM. The selection of patients for the interviews was based on several strategies. Results: In order to understand the patients’ experiences and positions of CAM......Background and objectives: There have not earlier been studies focusing on experiences of Danish diabetic patients using Complementary and Alternative Medicine (CAM) – considered from the patients’ point of view. The existing studies mostly based on quantitative methods of patients with diabetes...... prevalence in use of CAM, which is generally rather low, especially the CAM used specifically for diabetes. The objective of this paper is to develop concepts to understand patients having experiences and positions of diabetes in their use of CAM. Methods: This qualitative study its inspiration from grounded...

  19. Overlevelse efter lynnedslag og behandling af tilstødende komplikationer

    DEFF Research Database (Denmark)

    Pedersen, Malene Lægdsgaard; Uslu, Bülent; Lind, Morten Nikolaj;

    2011-01-01

    Lightning strike is an unpredictable weather phenomenon which can cause a variety of injuries to the human body. We present a case report with a 24-year-old male football player, who survived prolonged cardiac arrest after a lighting strike and then presented with multiple organ dysfunction due...

  20. Organtransplanterede patienter har behov for intensiv kontrol og behandling af hudcancer

    DEFF Research Database (Denmark)

    Togsverd-Bo, Katrine; Sørensen, Søren Schwartz; Hædersdal, Merete

    2013-01-01

    The risk of non-melanoma skin cancer (NMSC) and in particular squamous cell carcinoma is significantly increased in organ transplant recipients due to long-term treatment with immunosuppressives. Dermatologic management in the form of a multidisciplinary approach, including patient education, skin...

  1. Behandling af kardiogent shock med perkutan mekanisk cirkulationsstøtte

    DEFF Research Database (Denmark)

    Junker, Anders; Kaltoft, Anne; Hassager, Christian

    2013-01-01

    Despite rapid revascularisation with circulatory support using inotropes and intra-aortic balloon counterpulsation, the mortality of cardiogenic shock complicating acute myocardial infarction still exceeds 50%. An alternative treatment strategy is restoration of cardiac output by using a ventricu......Despite rapid revascularisation with circulatory support using inotropes and intra-aortic balloon counterpulsation, the mortality of cardiogenic shock complicating acute myocardial infarction still exceeds 50%. An alternative treatment strategy is restoration of cardiac output by using...... a ventricular assist device which can be inserted in the acute setting using the Impella device, a catheter-based flow pump. DanShock is a Danish multicentre study that will assess whether circulatory support using the Impella device will improve the outcome of cardiogenic shock compared to conventional...

  2. Fra mental retardering til målrettet behandling ved fragilt X-syndrom

    DEFF Research Database (Denmark)

    Jønch, Aia Elise; Timshel, Susanne; Carlsen Lunding, Jytte Merete;

    2014-01-01

    From intellectual disability to new treatment modalities of fragile X syndrome: Ugeskr Læger 2014;176:V06130350 In 1943 a large family with X-linked mental retardation was described by Martin & Bell. This family had what we know today as fragile X syndrome, the most common inherited form...... of intellectual disability. Current knowledge about the specific gene, the encoded protein and the pathophysiological mechanisms involved has made it possible to develop pharmacological treatment trials. Fragile X syndrome therefore is on its way as model disorder for targeted treatments in genetic medicine...

  3. Medikamentel behandling af cancerrelateret traethed--en gennemgang af et Cochrane-review

    DEFF Research Database (Denmark)

    Pedersen, Lise; Palshof, Torben

    2009-01-01

    and multidimensional phenomenon Apart from erythropoietin and to some degree methylphenidate, there is no evidence that pharmacologic intervention may reduce CRF. CRF has major impact on quality of life for most patients suffering from a cancer disease. It is therefore of obvious importance to increase the focus...... on CRF - both in the pharmaceutical industry and in the professional-medical environment. Udgivelsesdato: 2009-Sep...

  4. Intermitterende pneumatisk kompressions-behandling ved underekstremitetsiskæmi uden kirurgiske behandlingstilbud

    DEFF Research Database (Denmark)

    Feuerhake, Ingrid Luise; Henneberg, Eskild W; Høgh, Annette

    2016-01-01

    Patients with critical limb ischaemia, without possibility for vascular surgery reconstruction, are a high selected population with a wide scale occurrence of co-morbidity and mortality. We outline the use of intermittent pneumatic compression (IPC) to these patients. Impact on both wound healing...... and cost-effectiveness concerning IPC use are recently shown. The overriding purpose of IPC use is to decrease the frequency of major and to lower the extent of ischaemic rest pain. IPC equipment is currently available around the country, but is not often used on the indication critical limb ischaemia....

  5. Systemisk prokinetisk behandling af postoperativ ileus efter abdominalkirurgi. Gennemgang af et Cochrane-review

    DEFF Research Database (Denmark)

    Holte, Kathrine

    2010-01-01

    Based on the evidence presented in the Cochrane review "Systemic prokinetic pharmacologic treatment for postoperative adynamic ileus following abdominal surgery in adults", routine administration of systemic prokinetics for the prevention of postoperative ileus is not recommendable. The potential...

  6. Svær laryngomalaci hos børn kan behandles med laserkirurgi

    DEFF Research Database (Denmark)

    Meyer, Lars Christian; Godballe, Christian

    2012-01-01

    Laryngomalacia is the most common cause for congenital stridor. The stridor is caused by collapse of supraglottic structures during inspiration. Two severe cases treated with laser-assisted supraglottoplasty are presented. Our cases as well as the literature describe good effect of the treatment...

  7. Danske anbefalinger for behandling af ankyloserende spondylitis og spondylartritis udarbejdet i et internationalt projektsamarbejde

    DEFF Research Database (Denmark)

    Pedersen, Susanne Juhl; Madsen, Ole Rintek; Erlendsson, Jon

    2008-01-01

    INTRODUCTION: The multinational initiative "3e Initiative in Rheumatology - Multi-national Recommendations for the Management of Ankylosing Spondylitis 2006-7" served the primary purpose of providing specific recommendations for the management of ankylosing spondylitis and spondyloarthritis...

  8. Patient med nedsat leverfunktion fik myoklonier under behandling med selektive serotoningenoptagelseshæmmere

    DEFF Research Database (Denmark)

    Forsberg-Gillving, Mimmi; Bode, Matthias; Sindrup, Søren Hein

    2015-01-01

    Side effects such as myoclonus and tremor are rare when treating with selective serotonin reuptake inhibitors (SSRIs). We present a case where a patient with known liver cirrho-sis and in treatment with citalopram developed myoclonus, tremor and gait difficulties. The symptoms were reduced when...

  9. Forebyggelse og behandling af fedme hos børn og unge

    DEFF Research Database (Denmark)

    Michaelsen, Kim Fleischer; Mølgaard, Christian; Richelsen, Bjørn

    2006-01-01

    In the last 10 years, there has been a marked increase in the prevalence of obesity in children beginning at 3-4 years of age. The only realistic solution to the problem is prevention. Although there is limited evidence for the effectiveness of preventive programmes, there is a consensus...... that multisectorial action is urgently needed. This should include intervention at the family, school, municipal, regional and national levels, including the commercial sector and food companies. Treating childhood obesity has not been very successful, but some comprehensive community-based treatment programmes have...

  10. Manglende evidens for skadelig effekt på knogleheling ved behandling med NSAID

    DEFF Research Database (Denmark)

    Janum, Susanne; Kristensen, Billy Bjarne

    2012-01-01

    discard of NSAID for postoperative pain relief in uncomplicated cases. However, NSAID should be considered a potentiel risk factor of impaired bone healing and avoided in patients with a high risk of pseudoarthrosis. Recommended daily doses should be respected and duration of treatment should be limited....

  11. Behandling af uraemisk osteodystrofi med laegemidler, som påvirker calcium-fosfor-omsaetningen

    DEFF Research Database (Denmark)

    Vestergaard, Peter; Eiken, Pia A

    2012-01-01

    This review discusses the mineral bone disorders in patients with chronic kidney disease. We focus on the management of these conditions by administration of calcium, vitamin D (ergocalciferol and cholecalciferol), vitamin D receptor activators (calcitriol, alphacalcidiol), phosphate binders...

  12. Integrert behandling av rus og psykiske lidelser i en sikkerhetspsykiatrisk avdeling: Evaluering av implementeringstiltak

    Directory of Open Access Journals (Sweden)

    Kari E. Bjørnstad

    2014-06-01

    Full Text Available Integrated treatment of substance abuse and mental illness in a security psychiatric ward: Evaluation of the implementation measures Violence and homicide among patients with severe mental disorders is associated with substance use. The main aim of this study was to improve organization-level dual diagnoses capability in a forensic psychiatric unit. Health personnel and organization level assessments were performed before and after program and staff training and program implementation. Results: The DDCMHT targeted important areas of change and staff training was associated with an increased total score in dual diagnoses capability from 2.7 to 3.9 on a 1-5 scale, a change from being categorized as Addiction or Mental health Services Only to Dual Diagnosis Capable. Important implementation factors were clinical experience and organizational support. Despite implementation challenges, the main conclusion to be drawn from the study is that improvements in dual diagnoses capability are feasible at a service level.

  13. Forekomst, kausalitet og behandling af polyneuropati associeret til monoklonal gammopati af ukendt signifikans

    DEFF Research Database (Denmark)

    Moth Henriksen, Marie; Kolmos, Eva Brøsted; Abildgaard, Niels;

    2012-01-01

    The prevalence of polyneuropathy in patients with monoclonal gammopathy of undetermined significance (MGUS) has been reported to be 10-50%. The majority of patients have a chronic, slowly progressive, distal, symmetric and predominantly sensory polyneuropathy. A caused relationship between...

  14. Akut iliofemoral venøs trombose bør behandles med kateterbaseret trombolyse

    DEFF Research Database (Denmark)

    Broholm, Rikke; Just, Sven; Jørgensen, Maja;

    2012-01-01

    Treatment of acute iliofemoral deep venous thrombosis (DVT) with catheter-directed thrombolysis (CDT) has been performed in Denmark since 1999. The purpose of CDT is to dissolve thrombus and to restore the venous lumen as fast as possible and thereby save venous valve function and prevent...... postthrombotic syndrome. Danish studies have shown that treatment of acute iliofemoral DVT using CDT results in good patency, preserves venous valve function, reduces the frequency of PTS, and is associated with a higher quality of life....

  15. Angioneurotisk ødem i forbindelse med behandling med angiotensinkonverterende enzym-haemmer

    DEFF Research Database (Denmark)

    Johansen, E C; Johansen, J B; Døssing, H

    1996-01-01

    illustrate problems in the diagnosis and management of this life-threatening condition, and also demonstrate that angioedema re-occurs if the ACE inhibitor is not discontinued. If angioedema is suspected, therapy with any angiotensin converting-enzyme inhibitor should be discontinued promptly, respiratory...... distress should be treated appropriately, and subsequent therapy should be initiated with an agent from an alternative class of drugs....

  16. Konsensus for behandling og kontrol af borderline-tumor i ovariet i Danmark

    DEFF Research Database (Denmark)

    Lundvall, L; Lund, B A; Hansen, M

    1990-01-01

    In order to obtain an impression of the consensus in Denmark of the treatment and control of border-line tumours of the ovary (BTO), a questionnaire was sent to all 43 departments of gynaecology/obstetrics and of surgery with gynaecology/obstetrics. Thirty-seven (86%) departments replied. The res...... for radiotherapy. Treatment and control of BTO in Denmark are in agreement with current international principles....

  17. Behandling af svær anæmi hos patienter, der afviser blodtransfusion

    DEFF Research Database (Denmark)

    Lorentzen, Kristian; Kjær, Bjarne; Olsen, Karsten Skovgaard

    2014-01-01

    In situations involving serious bleeding and anaemia, a refusal of blood transfusion puts the clinician in an ethical and medical dilemma, as standard treatment is not an option, and the patient risks dying of a potentially reversible cause. This status article describes methods of treatment unde...... the concept of "bloodless medicine", where surgical and supportive techniques are used to manage and treat severe anaemia.......In situations involving serious bleeding and anaemia, a refusal of blood transfusion puts the clinician in an ethical and medical dilemma, as standard treatment is not an option, and the patient risks dying of a potentially reversible cause. This status article describes methods of treatment under...

  18. Medicinsk behandling af hypofosfatæmisk rakitis hos børn

    DEFF Research Database (Denmark)

    Rahbek, Elise Torp; Nielsen, Line Hougaard; Beck-Nielsen, Signe Sparre;

    2014-01-01

    regimen often fails to prevent bone deformity and reduced final height. The rarity and complexity of these diseases call for centralised specialist care and international collaboration. Future medical treatment may be improved by addition of new promising experimental treatments.......Hypophosphataemic rickets is a rare, genetic disorder resulting in defect bone mineralisation and rickets. The current medical treatment consists of phosphate supplementation and alfacalcidol, but side effects such as secondary hyperparat-hyroidism and nephrocalcinosis are common. This treatment...

  19. Radium-223 behandling af knoglemetastaser ved kastrationsrefraktær prostatacancer

    DEFF Research Database (Denmark)

    Mortensen, Jann; Højgaard, Liselotte

    2014-01-01

    The alpha emitter Radium-223 ((22)3Ra-Cl2) is a bone-seeking radionuclide studied as a new treatment for patients with bone metastases from hormone refractory prostate cancer. More than 1,000 patients have been included in clinical phase I-III tests showing significant reduction in alkaline...

  20. Tumornekrosefaktor alpha-haemning som led i behandling af uveitis hos børn

    DEFF Research Database (Denmark)

    Fledelius, Hans Callø; Nielsen, Susan M; Nissen, Kamilla Rothe

    2007-01-01

    To present our experience with anti-TNFalpha treatment of juvenile idiopatic arthritis (JIA) associated uveitis.......To present our experience with anti-TNFalpha treatment of juvenile idiopatic arthritis (JIA) associated uveitis....

  1. Toksoplasmose-chorioretinitis: klinisk forløb og behandling af syv patienter

    DEFF Research Database (Denmark)

    Lebech, A M; Lebech, M; Børme, K K

    1996-01-01

    Toxoplasmosis is a major and preventable cause of severe visual loss and blindness in young people. Ocular toxoplasmosis is the leading cause of posterior uveitis and in most cases it represents a late manifestation of a congenital infection. The clinical picture and anti-Toxoplasma therapy...

  2. Behandling af idiopatisk perifer facialisparese, også kaldet Bells parese

    DEFF Research Database (Denmark)

    Meyer, Martin Willy; Hahn, Christoffer Holst

    2013-01-01

    Bell's palsy is defined as an idiopathic peripheral facial nerve paralysis of sudden onset. It affects 11-40 persons per 100,000 per annum. Many patients recover without intervention; however, up to 30% have poor recovery of facial muscle control and experience facial disfigurement. The aim...

  3. Behandling og diagnostik af tuberkulose: fremad med små skridt

    DEFF Research Database (Denmark)

    Bengård Andersen, Åse; Lillebæk, Troels; Bang, Didi;

    2011-01-01

    Development of new drugs for the treatment of drug sensitive and drug resistent tuberculosis is badly needed. Substantial progress has been made in the field and presently six new drug components are in clinical phase I and II trials. Drugs approved for other indications e.g. newer fluoroquinolones...

  4. Segmentel vending af tyndtarmen til behandling af voksne patienter med korttarms syndrom

    DEFF Research Database (Denmark)

    Burgdorf, Stefan K; Qvist, Niels; Gögenur, Ismail

    2014-01-01

    Short bowel syndrome is the result of extensive surgical resection, inherited defects or loss of functional absorbing intestine. Parenteral nutrition is associated with high economical expenses, increased morbidity and decreased quality of life. Intestinal transplantation is associated with high...... morbidity and mortality rates. Segmental reversal of the small bowel can prolong the transit time in the small bowel and in many cases permanently end parenteral nutrition dependency. Segmental reversal of the small bowel should be integrated in the surgical treatment of adults with short bowel syndrome....

  5. Ventetid og omkostninger ved diagnostik og behandling af stabil angina pectoris

    DEFF Research Database (Denmark)

    Søgaard, Rikke; Sanchez, Ricardo

    Introduction: The objective of this pilot study was to examine possible consequences of a logistically non-optimal regimen, for the diagnosis and treatment of stable angina pectoris, on waiting time and costs to inform whether a larger study is warranted. Material and methods: Retrospective cohort...... study among 104 consecutive patients referred on suspected stable angina pectoris. Data on the diagnostic regimen was systematically collected from patient files and data on other resource use was collected using a questionnaire for self- reporting. Non-parametric bootstrapping was applied. Results...... of stable angina pectoris, which ceteris paribus would be associated with cost savings in the health care sector. However, these potentials should be examined in a larger- scale study....

  6. Sekundær prævention af apopleksi med effektiv antihypertensiv behandling

    DEFF Research Database (Denmark)

    Knudsen, Signe Boye; Strandgaard, Svend; Paulson, Olaf B.

    2013-01-01

    In this meta-analysis, four of five placebo-controlled studies showed that antihypertensive treatment prevented stroke recurrence, most markedly in a study with a combination of an angiotensin-converting enzyme inhibitor and a diuretic. Studies with beta-blockers were not included. Two head...

  7. Epstein-Barr-virus-associeret lymfom hos en patient med colitis ulcerosa i behandling med azathioprin

    DEFF Research Database (Denmark)

    Kofoed, Kristian; Kiszka-Kanowitz, Marianne; Albrectsen, Jens Mørch;

    2008-01-01

    A 28 year-old man with ulcerative colitis treated for 10 years with azathioprine (AZA) returned from Central Asia with fever, swollen lymph glands, hepatosplenomegaly, and pancytopenia. He was tested positive for acute Epstein-Barr virus (EBV) infection. Before the final diagnosis of EBV-associat......A 28 year-old man with ulcerative colitis treated for 10 years with azathioprine (AZA) returned from Central Asia with fever, swollen lymph glands, hepatosplenomegaly, and pancytopenia. He was tested positive for acute Epstein-Barr virus (EBV) infection. Before the final diagnosis of EBV...

  8. Fæcestransplantation som behandling af Clostridium difficile-infektion, colitis ulcerosa og metabolisk syndrom

    DEFF Research Database (Denmark)

    Carstensen, Jeppe West; Hansen, Axel Kornerup

    2014-01-01

    Faecal transplantation as a treatment for Clostridium difficile infection, ulcerative colitis and the metabolic syndrome Faecal transplantation as a therapeutic tool is increasingly reported in the scientific literature. Faecal transplantation is currently becoming a treatment for nosocomial......, refractory infections with C. difficile. Furthermore, faecal transplantation has been suggested as a treatment for ulcerative colitis as well as for the metabolic syndrome. In the accumulated literature faecal transplantations appear to be safe, effective and superior to current treatments. Faecal...

  9. Behandling med dopaminagonister i den tidlige fase af Parkinsons sygdom: gennemgang af et Cochrane-review

    DEFF Research Database (Denmark)

    Bode, Matthias

    2009-01-01

    The Cochrane analysis confirms some well-known facts: initial therapy with dopamine agonists (DA) delays the incidence of motor complications, but is associated with inferior motor control and a higher frequency of non-motor adverse events (AE) compared with levodopa. Some serious AE are missing...

  10. Endokrinologisk udredning, behandling og opfølgning af polycystisk ovariesyndrom

    DEFF Research Database (Denmark)

    Glintborg, Dorte; Rungby, Jørgen; Eskildsen, Peter;

    2010-01-01

    with PCOS or on how the syndrome should be treated. Women with PCOS have an increased risk of the metabolic syndrome upon diagnosis and increased long-term risk of type 2 diabetes, cardiovascular disease and endometrial cancer. In the present overview, we give recommendations for relevant follow......Polycystic ovary syndrome (PCOS) has a prevalence of 5-10% and is defined as oligomenorrhoea, hyperandrogenaemia and/or polycystic ovaries and the exclusion of other aetiologies for the patient's symptoms. There is currently no agreement on the initial evaluation programme for women referred...

  11. Udredning og behandling af osteoporose hos patienter med kronisk obstruktiv lungesygdom

    DEFF Research Database (Denmark)

    Eiken, Pia Agnete; Brask-Lindemann, Dorte; Vestbo, Jørgen;

    2012-01-01

    Patients with chronic obstructive pulmonary disease have a high risk of osteoporosis and fractures. We present an algorithm for the prevention and treatment of osteoporosis in patients with chronic obstructive pulmonary disease.......Patients with chronic obstructive pulmonary disease have a high risk of osteoporosis and fractures. We present an algorithm for the prevention and treatment of osteoporosis in patients with chronic obstructive pulmonary disease....

  12. Diagnose og behandling af osteoporose ved ikke-metastaserende cancer mammae

    DEFF Research Database (Denmark)

    Eiken, Pia Agnete; Hansen, Mogens; Kristensen, Bent;

    2011-01-01

    The prevention of cancer-treatment-induced bone loss due to chemotherapy and long-term adjuvant breast cancer therapy has a high priority. We present an algorithm for the prevention and treatment of osteoporosis during treatment of nonmetastatic breast cancer....

  13. Ny behandling af peritoneal karcinose fra kolorektal cancer. Cytoreduktiv kirurgi og hyperterm intraperitoneal kemoterapi

    DEFF Research Database (Denmark)

    Iversen, Lene Hjerrild; Rasmussen, Peter C; Laurberg, Søren

    2007-01-01

    Peritoneal carcinomatosis (PC) is commonly seen in colorectal cancer and is uniformly fatal. Cytoreductive surgery (CS) combined with hyperthermic intraperitoneal chemotherapy (HIIC) is a new treatment in strictly selected patients with PC. CS includes peritonectomy procedures and resection of in...

  14. Triage medfører hurtigere behandling af de mest syge

    DEFF Research Database (Denmark)

    Skriver, Claus; Lauritzen, Marlene Mauson Pankoke; Forberg, Jakob Lundager;

    2011-01-01

    Systematic process triage is a relatively unknown concept in Denmark. Currently there are no national recommendations regarding triage models for use in the emergency department (ED). Four medium-sized EDs from different regions across the country cooperated in a joint venture to develop a new...

  15. Screening for tuberkuloseinfektion før behandling med biologiske lægemidler

    DEFF Research Database (Denmark)

    Ravn, Pernille

    2011-01-01

    Tumour necrosis factor antagonists (anti-TNFα) have become an invaluable treatment against chronic inflammatory diseases. Individuals treated with anti-TNFα have more than a fourfold increased risk of tuberculosis (TB) reactivation depending on the clinical setting and the TNF-antagonist used. All...... candidates for anti-TNFα treatment in Denmark should be evaluated for possible latent TB using history of exposure, chest X-ray and an interferon-γ release assay. Preventive chemotherapy is recommended for all individuals with latent TB infection before initiation of anti-TNFα as it is expected to reduce...

  16. Vellykket behandling af supraventrikulær takykardi med modificeret Valsalvas manøvre

    DEFF Research Database (Denmark)

    Wallentin, Johan; Sjøl, Anette

    2016-01-01

    Supraventricular tachycardia (SVT) is a frequent challenge in medical emergency units. Adenosine, the drug of choice, may cause severe discomfort. The Danish Society of Cardiology's National Treatment Guidelines for SVT recommend first aid treatment with ''vagus stimulation such as carotid massage...

  17. Komplementær og alternativ behandling på socialpsykiatriske bosteder

    DEFF Research Database (Denmark)

    Lunde, Anita

    2016-01-01

    -processer. Kontakt til flere socialpsykiatriske bosteder har vist, at eksempelvis massage og øreakupunktur tilbydes som supplement til bostøtte. Disse metoder er dog kun sparsomt belyst og evalueret. Dette forskningsprojekt vil undersøge brugen af KAB i socialpsykiatrien i Region Syddanmark og Midtjylland, samt om...

  18. Risiko for anastomoselækage ved postoperativ behandling med nonsteroide antiinflammatoriske stoffer

    DEFF Research Database (Denmark)

    Klein, M.; Gögenür, Ismayil; Rosenberg, J.

    2010-01-01

    strength and reduced deposition of hydroxyproline. Retrospective human studies have reported increased leakage rates after postoperative diclofenac and celecoxib treatment. We recommend that diclofenac and celecoxib be omitted from analgesic regimens after colorectal surgery involving an anastomosis...

  19. Kardiovaskulære risici ved behandling med nonsteroide antiinflammatoriske lægemidler

    DEFF Research Database (Denmark)

    Schmidt, Morten; Fosbøl, Emil Loldrup; Torp-Pedersen, Christian

    2016-01-01

    cyclooxygenase-2 inhibitors has been associated with a substantial vascular risk but increasing concern also relates to traditional NSAIDs, in particular diclofenac. This review summarizes the current evidence regarding the cardiovascular safety of NSAIDs and presents recommendations for their use....

  20. Lægers tavshedspligt ved behandling af unge kan være et dilemma

    DEFF Research Database (Denmark)

    Boisen, Kirsten; Adolphsen, Caroline; Svensson, Jannet;

    2016-01-01

    to treatment. Young people value confidentiality, although they are unaware of the current guidelines. International guidelines on youth-friendly health services recommend split visits and confidential care while at the same time acknowledging parents' caretaking role, especially in adolescents with chronic...

  1. Behandling af højt blodtryk hos patienter med akut apopleksi

    DEFF Research Database (Denmark)

    Olsen, T S; Jørgensen, H S; Garde, E;

    1995-01-01

    The study was performed to investigate how often reduction of high blood pressure (> or = 220 mmHg systolic and or > or = 120 mmHg diastolic) was attempted in patients with acute stroke or transient ischemic attacks (TIA). Of 1351 consecutive patients with acute stroke or TIA 119 had high blood...

  2. Diagnostik og behandling af kvinder med urin-inkontinens på danske gynaekologiske afdelinger

    DEFF Research Database (Denmark)

    Vejtorp, M; Fischer-Rasmussen, W; Blaabjerg, J

    1990-01-01

    The routine practice in the diagnosis and treatment of urinary incontinence was investigated by means of a questionnaire to which all 32 departments replied. Miction charts were employed routinely in 17 departments and for selected patients in eight departments. Weighing of diapers was employed...

  3. Danske anbefalinger for behandling af ankyloserende spondylitis og spondylartritis udarbejdet i et internationalt projektsamarbejde

    DEFF Research Database (Denmark)

    Pedersen, Susanne Juhl; Madsen, Ole Rintek; Erlendsson, J.

    2008-01-01

    INTRODUCTION: The multinational initiative "3e Initiative in Rheumatology - Multi-national Recommendations for the Management of Ankylosing Spondylitis 2006-7" served the primary purpose of providing specific recommendations for the management of ankylosing spondylitis and spondyloarthritis....... Systematic literature searches were performed in Medline by 3 international and a Danish bibliographic fellow. Outcome data were extracted and processed by use of routine methods from clinical epidemiology and statistics. The evidence was presented to the Danish rheumatologists. The participants were divided...... of these in the analysis. All 186 Danish rheumatologists were invited, and 26 (14,0%) participated in the meeting held in Copenhagen, December 2006. The individual recommendations were endorsed by 68-100% of the participants. CONCLUSION: Within the framework of the multinational 3e project, it was possible to develop...

  4. Laparoskopisk versus åben højresidig hemikolektomi til behandling af koloncancer

    DEFF Research Database (Denmark)

    Pommergaard, H C; Olsen, J.A.; Burgdorf, S.K.;

    2010-01-01

    , blood loss, surgical complications and mortality. RESULTS: The length of hospital stay was significantly shorter in the LRH group than in the ORH group (five vs. six, p = 0.023). Furthermore, the number of lymph nodes harvested was significantly larger in the LRH group than in the ORH group (23 vs. 15......, p complications including anastomotic leaks (eight vs. 14) and lower operation-related mortality (zero vs. three). None of these differences were statistically significant. CONCLUSION: LRH is comparable...... to ORH with regards to morbidity, mortality and blood loss. Furthermore, LRH is associated with a shorter hospital stay and a higher radical lymph node harvest than ORH. The results and the thesis that LRH will result in fewer hernias and better cosmetic outcomes makes LRH a promising surgical procedure...

  5. Konservativ behandling af sårinfektioner efter operation for mammacancer

    DEFF Research Database (Denmark)

    Lanng, Charlotte; Hoffmann, Jack

    2002-01-01

    treated conservatively with repeated aspiration or replacement of the drain, 5% had spontaneous perforation of the wound abscess, corresponding to a small area of necrosis, and healed without operation. Five per cent had a major area of necrosis with underlying infections. These patients had their wound...

  6. Hageterapi som behandling av psykiske lidelser: En systematisk litteraturgjennomgang av mulige virkningsmekanismer

    OpenAIRE

    Jervidalo, Tora Larsen

    2015-01-01

    Horticultural therapy is a treatment intervention that use garden environment and gardening to achieve therapeutic changes. This systematic mixed methods review is an attempt to achieve a greater understanding of why horticultural therapy works, by a) examine what the available research on horticultural therapy as treatment of mental illness suggest in terms of possible mechanisms of change associated with the relationship between nature and human, and b) evaluate the empirical findings in th...

  7. Diabetisk ketoacidose hos en hiv-positiv patient i antiretroviral behandling

    DEFF Research Database (Denmark)

    Holm, Malene Rahbek; Hansen, Birgitte Rønde; Røder, Michael E

    2006-01-01

    inhibitors (PI), in particular, has been associated with insulin resistance and hyperglycaemia, but only infrequently with diabetic ketoacidosis. We report a case of diabetic ketoacidosis in an HIV-infected woman after 1(1/2) years of a PI-containing regimen, demonstrating reduced beta cell function...... and insulin resistance. Udgivelsesdato: 2006-Feb-27...

  8. Begrænset evidens for bedste behandling af ukompliceret galdestenssygdom

    DEFF Research Database (Denmark)

    Rasmussen, Martin; Schulze, Svend; Bisgaard, Thue

    2016-01-01

    be cholecystectomy or watchful waiting is weak. This narrative-condensed review critically analyses current evidence with special focus on epidemiological risk factors of developing symptoms or complications related to gallbladder stones. The evidence for treatment is discussed.......Gallbladder stones will rarely lead to colic pain attacks and even more seldom to complications. A conservative watchful waiting strategy may be an alternative to cholecystectomy for uncomplicated symptomatic gallbladder stone disease. Evidence for whether the optimal treatment should...

  9. Disease-modifying anti-rheumatic drugs til behandling af ankyloserende spondylitis

    DEFF Research Database (Denmark)

    Madsen, Ole Rintek; Egsmose, Charlotte

    2009-01-01

    Ankylosing spondylitis (AS) is an inflammatory disorder affecting the axial skeleton, peripheral joints, entheses and extra-articular sites. Patients with early disease, a higher level of erythrocyte sedimentation rate and/or peripheral arthritis might benefit from sulfasalazine. Otherwise...

  10. Serumelektrolytter og medikamentel behandling hos patienter indlagt på en geriatrisk afdeling

    DEFF Research Database (Denmark)

    Sørensen, I J; Matzen, L E

    1993-01-01

    . Risk factors for low sodium concentrations were treatment with the combination of thiazide+amiloride, potassium-sparing diuretics, thiazides, emergency hospitalization and low body weight. Risk factors for low potassium concentrations were treatment with the combination of thiazide+amiloride, thiazides...

  11. Mulig forbedret behandling af kolorektal cancer med sentinel lymph node-diagnostik

    DEFF Research Database (Denmark)

    Burgdorf, Stefan K; Eriksen, Jens Ravn; Gögenür, Ismail

    2014-01-01

    Possibly improved treatment of colorectal cancer by sentinel lymph node mapping Prognosis for colorectal cancer is dependent on radical surgical intervention. Chemotherapy in patients with advanced disease has improved the survival. A considerable proportion of the patients going through radical...... surgery will subsequently relapse. Adjuvant chemotherapy is reserved for patients with lymph node metastases, why undetected malignant lymph nodes will result in understaging and exclusion from the possible benefit of adjuvant chemotherapy. With sentinel lymph node mapping it may be possible to detect...

  12. Alternativ behandling i Danmark--brug, brugere og årsager til brug

    DEFF Research Database (Denmark)

    Lønroth, Helle Langhoff; Ekholm, Ola

    2006-01-01

    : The survey revealed that 40.2% had ever used CAM and 20.1% had used CAM within the last year. Of those reporting having used CAM ever, reflexology (22.7%), massage/osteopathy/other manipulative techniques (16.5%) and acupuncture (16.2%) were the most frequently used. The use of CAM was more common among....... CAM was used mainly to treat mild symptoms/diseases (39%) and as prevention or for increased well-being (22%). More women than men stated that they wished to take an active part in their own treatment (30% versus 14%) and cited the unwanted side effects of conventional medicine (16% versus 7...

  13. Glucagon-like peptide 1-baseret behandling af type 2-diabetes mellitus

    DEFF Research Database (Denmark)

    Knop, Filip Krag; Vilsbøll, Tina

    2007-01-01

    GLP-1 is secreted from the small intestine in response to ingestion of nutrients. It has a powerful insulinotropic effect and stimulates beta-cell growth and is therefore being developed for treatment of type 2 diabetes. The GLP-1 analogue, exenatide, is on the market in the USA as an add......-on therapy. Another strategy to increase circulating GLP-1 is to inhibit the enzyme DPP-IV which degrades endogenous GLP-1. GLP-1-based therapy results in HbA1c reductions of approximately 1 percent point, and the lack of serious side effects and the low risk of hypoglycaemic episodes are unique traits....

  14. Effekt af trombolytisk behandling på udfaldet af tidlig arbejdstest hos patienter med akut myokardieinfarkt

    DEFF Research Database (Denmark)

    Svendsen, Jesper Hastrup; Madsen, J K; Saunamäki, K I;

    1994-01-01

    Exercise test variables, such as an impaired heart rate response, are known to be related to left ventricular function and patient prognosis following acute myocardial infarction. The present study was performed to compare exercise test variables in acute myocardial infarct patients following eit...

  15. Behandling og rehabilitering på apopleksiafsnit øger 5-års-overlevelsen

    DEFF Research Database (Denmark)

    Jørgensen, H S; Kammersgaard, L P; Nakayama, H;

    2000-01-01

    in the stroke unit had higher comorbidity with regard to hypertension and diabetes. Multivariate linear and logistic regression analyses were applied to estimate the independent influence of stroke unit treatment on outcome. Stroke unit treatment significantly reduced not only initial mortality, but also...... mortality within five years from stroke onset. The relative risk of dying within the first five years from stroke was reduced by 40%, p nursing home, reduces cost of treatment...

  16. Antihypertensiv behandling forud for cerebrovaskulaere sygdomme er utilstraekkelig i henhold til rekommandationerne

    DEFF Research Database (Denmark)

    Nielsen, Aneta Aleksandra; Christensen, Cramer; Brandslund, Ivan;

    2008-01-01

    INTRODUCTION: Hypertension, diabetes mellitus and age are risk factors for cerebrovascular events. The aim of this study was to investigate the presence of hypertension, diabetes and antihypertensive treatment preceding disease debut in patients admitted to hospital with cerebrovascular events...... with antihypertensives and 80% had blood pressure >/= 140/90. The remaining 41% of all patients received no antihypertensive treatment, though 66% had elevated blood pressure. CONCLUSIONS: A total of 74% of all patients had increased blood pressure before hospital admittance. Our study shows that management...... of hypertension is unsatisfactory, and many cerebrovascular events may be prevented through improved detection of unknown hypertension and more intensive anti-hypertensive treatment. Udgivelsesdato: 2008-Oct-6...

  17. Indikation for behandling med warfarin bør altid fremgå eksplicit ved sektorskifte

    DEFF Research Database (Denmark)

    Vestergaard, Thea; Hjort, Johanne; Madsen, Henrik Bjørnsgaard;

    2014-01-01

    Warfarin has a narrow therapeutic window and side effects include bleeding causing e.g. hospital admission and death. Monitoring of treatment and review of indication are mandatory. We report a case of more than four years of warfarin treatment without indication. Treatment was not discontinued due...... to inadequate medical record keeping and communication among health-care providers. Medical-record keeping should follow guidelines from the National Board of Health. In addition, clearly stated treatment duration and indication may prevent unwarranted or premature termination of treatment....

  18. Nonoperativ behandling af alvorlige stumpe pancreaslæsioner hos børn

    DEFF Research Database (Denmark)

    Penninga, Luit; Hillingsø, Jens

    2011-01-01

    Diagnosis and treatment of pancreatic trauma in children is challenging. Grade I and II lesions of the pancreas (Organ Injury Scale of the American Association of Trauma) are generally treated non-operatively. However, the optimal treatment of pancreatic lesions with involvement of the pancreatic...

  19. Prognostiske faktorer af betydning for den recidivfrie overlevelse efter kirurgisk behandling af hoved-hals-melanom

    DEFF Research Database (Denmark)

    Andersson, A P; Gottlieb, J; Søndergaard, K;

    1993-01-01

    The clinico-pathological and therapeutic data of 512 patients with clinical stage I invasive head and neck melanoma of the skin were re-evaluated. There were 287 females and 225 males. The median age at primary surgery was 65 years, range 18 to 96 years. The median observation period was 5 years...

  20. Svær hyponatriæmi ved Terlipressin behandling

    DEFF Research Database (Denmark)

    Poulsen, Anja; Krag, Aleksander

    2013-01-01

    to terlipressin treatment. A 60-year-old woman with bleeding oesophageal varices was treated with terlipressin 2 mg every fourth hour. After 24 hours of treatment she was somnolent, and the sodium concentration had dropped from 127 mmol/l to 107 mmol/l. Hyponatraemia is an important adverse event in terlipressin...

  1. Blødningskomplikationer ved behandling med clopidogrel og acetylsalicylsyre efter akut koronart syndrom

    DEFF Research Database (Denmark)

    Kjær, Janus; Larsen, Christian Hastrup; Poulsen, Tina Svenstrup

    2006-01-01

    INTRODUCTION: The Clopidogrel in Unstable Angina to Prevent Recurrent Events (CURE) study showed that patients with unstable angina pectoris (UAP) and non-ST-elevation myocardial infarction (NSTEMI) benefit from combined therapy with acetylsalicylic acid (ASA) and clopidogrel. However, only...

  2. Udvikling og behandling af delirium hos kritisk syge børn

    DEFF Research Database (Denmark)

    Winther-Olesen, Marie; Afshari, Arash

    2012-01-01

    Delirium is a common and often under-recognised neuropsychiatric disorder in paediatric critical care, secondary to a general medical condition. Paediatric delirium (PD) is associated with high morbidity and mortality and prolonged stay at the intensive care unit. This review introduces the reader...

  3. Idrætstraumatologi og artroskopi--fra videnskab til klinisk behandling

    DEFF Research Database (Denmark)

    Krogsgaard, Michael Rindom

    2012-01-01

    Since the first knee arthroscopy in 1912, it is routine to scope all joints and many extra-articular structures. The effect of arthroscopic procedures in overuse conditions is sparsely documented and should be investigated in randomized studies, but score systems to evaluate clinical effects are ...... are lacking. An increased understanding of tissue reaction to loading and ligament healing as well as neuromuscular control is likely to change the basic principles of treatment and prevention in relation to sports injuries....

  4. Academic Performance of Students with the Highest and Mediocre School-leaving Grades: Does the Aptitude Test for Medical Studies (TMS) Balance Their Prognoses?

    Science.gov (United States)

    Kadmon, Guni; Kadmon, Martina

    2016-01-01

    Hintergrund: Die Auswahl Medizinstudierender wird in Deutschland teils zentral, teils lokal durchgeführt. Die zentrale Auswahl umfasst zwei Gruppen: Studierende mit den besten Hochschulzulassungsnoten (Abiturbeste) und Studierende mit schlechteren Abiturnoten, die erst nach einer Wartezeit von bis zu sieben Jahren nach Schulabschluss zum Studium zugelassen werden (Wartezeitquote). Studierende mit Lernschwierigkeiten sowie solche, die das Studium frühzeitig abbrechen, befinden sich in beiden Gruppen. Die hochschuleigene Studierendenauswahl (AdH) unserer Fakultät berücksichtigt das Ergebnis des Tests für Medizinische Studiengänge (TMS) und ermöglicht die leistungsbezogene Zulassung von Studierenden mit einer breiten Spannweite an Abiturnoten. Ziel: Zu untersuchen, ob die Gewichtung des TMS in der hochschuleigenen Auswahl gerechtfertigt ist, die darauf abzielt, die Zulassung potentiell leistungsschwacher Abiturbesten zu reduzieren und stattdessen die Zulassung potentiell leistungsstarker Bewerber zu fördern, die mittelmäßige Schulabgangsnoten mitbringen.Methode: Der prognostische Beitrag der Abiturpunktzahl und des TMS zur Studienleistung und zur Studienkontinuität im vorklinischen Abschnitt des Medizinstudiums wurde an zwei Studierendengruppen untersucht: Abiturbeste (Abiturnote 1,0, Abiturpunkte 823-900) und mittelmäßige Abiturienten (Abiturnoten 2,0-2,3, Abiturpunkte 689-660). Das Outcome beider Gruppen wurde im Verhältnis zu ihren TMS-Ergebnissen verglichen. Die Studie umfasste vier aufeinander folgende Kohorten. Ergebnisse: In beiden Gruppen sagte der TMS die Studienleistung (β=0,442-0,446) und die Studienkontinuität (OR=0,890-0,853) besser vorher als die Abiturnote (β=0,238-0,047; OR=1,009-0,998). Die Studienverlängerungs- und -abbruchsrate war am stärksten mit der Nicht-Teilnahme am TMS assoziiert (OR=0,230-0,380). Studierende mit mittelmäßigen Abiturnoten und TMS-Ergebnissen (standardisiertem Testwert) ≥125 erzielten ähnlich gute Studienleistungen wie die Abiturbesten. Mittelmäßige Schulabgänger mit TMS-Ergebnissen zwischen 110-124 erbrachten im Schnitt weniger gute aber noch ausreichende Studienleistungen. Abiturbeste mit mittelmäßigen TMS-Ergebnissen und 30% der Abiturbesten, die nicht am TMS teilgenommen hatten, erreichten nicht das Studienleistungsniveau der meisten Studierenden mit mittelmäßigen Abiturnoten und sehr guten TMS-Leistungen. Diskussion: Der TMS scheint, zwischen potenziell erfolgreichen und weniger erfolgreichen Studierenden beider Abiturnotenbereiche zu differenzieren. Mittelmäßige Abiturienten mit besonders hohen TMS-Ergebnissen erreichten bessere Studienergebnisse im vorklinischen Studienabschnitt als die Abiturbesten, die im TMS nur mittelmäßigen Erfolg hatten. Diese Beobachtungen rechtfertigen die Anwendung des TMS, um die Chancen von Studienbewerbern mit mittelmäßigen Abiturnoten am Wettbewerb um die Studienplätze zu erhöhen.

  5. Between prophecies and prognoses: Januário da Cunha Barbosa, slavery, and the future of the nation (1830-1836

    Directory of Open Access Journals (Sweden)

    Danilo José Zioni Ferretti

    2014-01-01

    Full Text Available This article aims at understanding the role played by the discussions about slavery and slave trafficking in the literate culture of Brazil in the 19th century, especially regarding the forms of figuring out the future of the nation. The way Canon Januário da Cunha Barbosa, an important politician and an illustrated intellectual, related projections of the future of the nation and treated the slavery issue (from 1830 to 1836 is analyzed. We discuss the use of projection modalities: prophecy and prognosis. Through them, Januário was involved in political discussions regarding the end of slave trafficking, and made political use of the Malê Revolt and Haitianism. The constitution of a horizon of antislavery expectation is indicated by the Canon, which is seen as one of the reasons to create the Brazilian Historic and Geographic Institute (1838.

  6. Comparison of Existing Clinical Scoring Systems in Predicting Severity and Prognoses of Hyperlipidemic Acute Pancreatitis in Chinese Patients: A Retrospective Study.

    Science.gov (United States)

    Qiu, Lei; Sun, Rui Qing; Jia, Rong Rong; Ma, Xiu Ying; Cheng, Li; Tang, Mao Chun; Zhao, Yan

    2015-06-01

    It is important to identify the severity of acute pancreatitis (AP) in the early course of the disease. Clinical scoring systems may be helpful to predict the prognosis of patients with early AP; however, few analysts have forecast the accuracy of scoring systems for the prognosis in hyperlipidemic acute pancreatitis (HLAP). The purpose of this study was to summarize the clinical characteristics of HLAP and compare the accuracy of conventional scoring systems in predicting the prognosis of HLAP. This study retrospectively analyzed all consecutively diagnosed AP patients between September 2008 and March 2014. We compared the clinical characteristics between HLAP and nonhyperlipidemic acute pancreatitis. The bedside index for severity of acute pancreatitis (BISAP), Ranson, computed tomography severity index (CTSI), and systemic inflammatory response syndrome (SIRS) scores were applied within 48 hours following admission. Of 909 AP patients, 129 (14.2%) had HLAP, 20 were classified as severe acute pancreatitis (SAP), 8 had pseudocysts, 9 had pancreatic necrosis, 30 had pleural effusions, 33 had SIRS, 14 had persistent organ failure, and there was 1 death. Among the HLAP patients, the area under curves for BISAP, Ranson, SIRS, and CTSI in predicting SAP were 0.905, 0.938, 0.812, and 0.834, 0.874, 0.726, 0.668, and 0.848 for local complications, and 0.904, 0.917, 0.758, and 0.849 for organ failure, respectively. HLAP patients were characterized by younger age at onset, higher recurrence rate, and being more prone to pancreatic necrosis, organ failure, and SAP. BISAP, Ranson, SIRS, and CTSI all have accuracy in predicting the prognosis of HLAP patients, but each has different strengths and weaknesses.

  7. Single-Fraction Versus 5-Fraction Radiation Therapy for Metastatic Epidural Spinal Cord Compression in Patients With Limited Survival Prognoses: Results of a Matched-Pair Analysis

    Energy Technology Data Exchange (ETDEWEB)

    Rades, Dirk, E-mail: Rades.Dirk@gmx.net [Department of Radiation Oncology, University Hospital Lubeck, Lubeck (Germany); Huttenlocher, Stefan [Department of Radiation Oncology, University Hospital Lubeck, Lubeck (Germany); Šegedin, Barbara; Perpar, Ana [Department of Radiotherapy, Institute of Oncology Ljubljana, Ljubljana (Slovenia); Conde, Antonio J.; Garcia, Raquel [Department of Radiation Oncology, Consorcio Hospital Provincial de Castellón, Castellón (Spain); Veninga, Theo [Department of Radiation Oncology, Dr Bernard Verbeeten Institute, Tilburg (Netherlands); Stalpers, Lukas J.A. [Department of Radiation Oncology, Academic Medical Center, Amsterdam (Netherlands); Cacicedo, Jon [Department of Radiation Oncology, Cruces University Hospital, Barakaldo, Vizcaya (Spain); Rudat, Volker [Department of Radiation Oncology, Saad Specialist Hospital, Al Khobar (Saudi Arabia); Schild, Steven E. [Department of Radiation Oncology, Mayo Clinic, Scottsdale, Arizona (United States)

    2015-10-01

    Purpose: This study compared single-fraction to multi-fraction short-course radiation therapy (RT) for symptomatic metastatic epidural spinal cord compression (MESCC) in patients with limited survival prognosis. Methods and Materials: A total of 121 patients who received 8 Gy × 1 fraction were matched (1:1) to 121 patients treated with 4 Gy × 5 fractions for 10 factors including age, sex, performance status, primary tumor type, number of involved vertebrae, other bone metastases, visceral metastases, interval between tumor diagnosis and MESCC, pre-RT ambulatory status, and time developing motor deficits prior to RT. Endpoints included in-field repeated RT (reRT) for MESCC, overall survival (OS), and impact of RT on motor function. Univariate analyses were performed with the Kaplan-Meier method and log-rank test for in-field reRT for MESCC and OS and with the ordered-logit model for effect of RT on motor function. Results: Doses of 8 Gy × 1 fraction and 4 Gy × 5 fractions were not significantly different with respect to the need for in-field reRT for MESCC (P=.11) at 6 months (18% vs 9%, respectively) and 12 months (30% vs 22%, respectively). The RT regimen also had no significant impact on OS (P=.65) and post-RT motor function (P=.21). OS rates at 6 and 12 months were 24% and 9%, respectively, after 8 Gy × 1 fraction versus 25% and 13%, respectively, after 4 Gy × 5 fractions. Improvement of motor function was observed in 17% of patients after 8 Gy × 1 fraction and 23% after 4 Gy × 5 fractions, respectively. Conclusions: There were no significant differences with respect to need for in-field reRT for MESCC, OS, and motor function by dose fractionation regimen. Thus, 8 Gy × 1 fraction may be a reasonable option for patients with survival prognosis of a few months.

  8. Surface settlements during the tunnel drivage in loose rock. Prognosis, measurement and impact; Oberflaechensetzungen beim Tunnelvortrieb im Lockergestein. Prognose, Messung und Beeinflussung

    Energy Technology Data Exchange (ETDEWEB)

    Fillibeck, Jochen [Technische Univ. Muenchen (Germany). Zentrum fuer Geotechnik

    2012-11-01

    The realistic prediction of supplement in tunnel construction is essential to secure the acceptance of the construction measure in the population. In addition to numerical calculations particularly empirical processes are suitable whose input variables are derived from previous experiences. Empirical methods use the Gaussian function for the description of the settlement trough arising from the tunnelling at the surface. The contribution under consideration describes the method of Fillibeck allowing the determination of the input parameters for shotcrete drivages and shield drivages. This empirical method was derived from a large number of carefully selected and inspected measuring cross-sections.

  9. Prognoses of MDS subtypes RARS, RCMD and RCMD-RS are comparable but cytogenetics separates a subgroup with inferior clinical course.

    Science.gov (United States)

    Bacher, Ulrike; Kern, Wolfgang; Alpermann, Tamara; Schnittger, Susanne; Haferlach, Claudia; Haferlach, Torsten

    2012-07-01

    In 2008, the WHO combined the former categories RCMD (refractory cytopenia with multilineage dysplasia) and RCMD-RS (ring sideroblasts ≥ 15%). We studied the clinical impact and genetic background of RARS, RCMD, and RCMD-RS in 1082 patients. Good karyotypes (IPSS) were similarly frequent in RARS, RCMD, and RCMD-RS. 2-year overall survival (OS) rates were similar in RARS, RCMD, and RCMD-RS (85.9%/89.0%/91.7%; n.s.). The 2-year OS rate was better in good than intermediate or poor karyotypes (pcytogenetic criteria for these MDS subtypes.

  10. A nationwide survey of clinical characteristics, management, and outcomes of acute kidney injury (AKI) - patients with and without preexisting chronic kidney disease have different prognoses.

    Science.gov (United States)

    Pan, Heng-Chih; Wu, Pei-Chen; Wu, Vin-Cent; Yang, Ya-Fei; Huang, Tao-Min; Shiao, Chih-Chung; Chen, Te-Chuan; Tarng, Der-Cherng; Lin, Jui-Hsiang; Yang, Wei-Shun; Sun, Chiao-Yin; Lin, Chan-Yu; Chu, Tzong-Shinn; Wu, Mai-Szu; Wu, Kwan-Dun; Chen, Yung-Chang; Huang, Chiu-Ching

    2016-09-01

    Acute kidney injury (AKI) is a common complication in hospitalized patients. The International Society of Nephrology implemented the "0 by 25" initiative aimed at preventing deaths from treatable AKI worldwide by 2025 and conducted a global snapshot survey in 2014. We joined in the project and conducted this study to compare the epidemiology, risk factors, and prognosis between patients with pure AKI and those with acute-on-chronic kidney disease (ACKD). In this study, we prospectively collected demographic parameters and data on clinical characteristics, baseline comorbidities, management, and outcomes of 201 AKI patients in 18 hospitals in Taiwan from September 2014 to November 2014. The in-hospital mortality rate was 16%. AKI was mostly attributed to sepsis (52%). Multivariate logistic regression indicated that oliguria was a positive independent predictor of in-hospital mortality, whereas preexisting CKD and exposure to nephrotoxic agents were negative independent predictors. The prevalence of vasopressor use, intensive care unit care, and mortality were significantly higher in pure AKI patients than in ACKD patients. Moreover, serum creatinine (SCr) levels significantly increased within 7 days after AKI diagnosis in nonsurvivors but not in survivors in the pure AKI group. By contrast, SCr levels were persistently lower in nonsurvivors than in survivors in the ACKD group during the same period. We thus determined that the prognosis of ACKD patients differed from that of pure AKI patients. Considering the CKD history in the future AKI staging system may improve prognosis prediction.

  11. Forecast with artificial neuronal network at Mycity Stadtwerke Uelzen; Prognose mit Kuenstlich Neuronalen Netzen bei Mycity Stadtwerke Uelzen. Modellierung der Energiebedarfsstruktur

    Energy Technology Data Exchange (ETDEWEB)

    Lehnguth, T. [SAE IT-Systems GmbH und Co. KG, Koeln (Germany). Kompetenzcenter NL-Chemnitz

    2004-06-14

    As a modern Power Utility Company, Mycity Stadtwerke Uelzen relies on High-Tech by the evaluation of future load behaviour. A self learning forecast, based on artificial neuronal networks, enables the modelling of power demand structures with a quality factor of 96% within seconds. (orig.)

  12. Behandling af renovaskulær hypertension med transluminal angioplastik--13 års erfaring--sekundærpublikation

    DEFF Research Database (Denmark)

    Øvrehus, Kristian Altern; Andersen, Poul Erik; Jacobsen, Ib Abildgaard

    2008-01-01

    The result of treatment of renovascular hypertension by renal angioplasty over a period of 13 years was analysed. Patients with a positive diagnostic work-up with renography or renal vein renin measurement had renal angiography performed and in cases of renal artery stenosis, transluminal...... angioplasty. A total of 124 patients were treated; 31% were normotensive immediately after angioplasty, 59% had improved blood pressure control and 10% had unchanged hypertension. The corresponding figures after six months and at the latest follow-up were 13, 72 and 15%. Udgivelsesdato: 2008-Jan-21...

  13. Kirurgisk behandling af renovaskulaer hypertension forårsaget af nyrearteriestenose. En retrospektiv opgørelse

    DEFF Research Database (Denmark)

    Hensler, M K; Forrest, M; Schroeder, T V;

    1994-01-01

    months. At follow-up (median 65 months), 85% of the patients had normal blood pressure or either no, modest or considerably reduced anti-hypertensive medication. It is concluded that surgical treatment of renovascular hypertension is a safe and effective procedure.......During a 10 year period 58 patients with renovascular hypertension due to renal artery stenosis were treated surgically. A retrospective analysis of the results was carried out. No perioperative mortalities occurred. Ten percent of the patients developed hypertension again after an average of 27...

  14. Behandling af akut myeloid leukæmi uden transfusion af blodprodukter hos et medlem af Jehovas Vidner

    DEFF Research Database (Denmark)

    Larsen, Christian; Jensen, Morten Krogh

    2011-01-01

    We present a case in which a young woman was diagnosed with acute myeloid leukaemia, FAB-classification type M2. As a member of Jehovah's Witnesses she refused to accept any treatment involving blood transfusions. A modified induction and consolidation chemotherapy regimen was applied, tailored...

  15. Intrauterin insemination med donorsaed. Behandling af ufrivillig barnløshed på grund af mandlig infertilitet

    DEFF Research Database (Denmark)

    Vilsbøll, Tina; Helmsøe-Zinck, Lise; Andersen, A N

    1994-01-01

    of conception and expected delivery was respectively 96% and 86%. The results show that intrauterine insemination with donor semen is a good treatment for couples with male infertility. Ultrasonic measurement of the follicles and timing of hCG injection were used for optimal timing of intrauterine donor...

  16. Fedmekirurgi er mere effektiv end medicinsk behandling til opnåelse af remission af type 2-diabetes

    DEFF Research Database (Denmark)

    Klein, Mads; Rosenberg, Jacob; Gögenur, Ismail

    2013-01-01

    Observational studies have shown that bariatric surgery can lead to remission of diabetes mellitus type 2 (DMII), but randomized controlled trials have been lacking. Recently, randomized controlled trials comparing bariatric surgery with optimal medical treatment in patients suffering from poorly...

  17. Heterotop graviditet efter IVF-behandling med excision af rumperet interstitiel graviditet og senere kejsersnit nær termin

    DEFF Research Database (Denmark)

    Elers, Jimmi; Zingenberg, Helle; Bing, Mette H;

    2016-01-01

    We describe a rare case of heterotopic pregnancy following in vitro fertilization with transferring of two embryos in a 39-year-old woman with previous bilateral salpingectomy. An ultrasound examination was performed on the day before admission showing a vital intrauterine pregnancy and no ectopic...... pregnancy. The woman was admitted with a ruptured cornual pregnancy at ten weeks of gestation. Laparotomy was performed on vital indication with excision of the ruptured haemorrhagic cornual pregnancy. The intrauterine pregnancy continued uneventfully with obstetric and fetal medicine specialist monitoring...

  18. Fatal blødning ved operation for hoftenær fraktur hos en patient i behandling med dabigatran

    DEFF Research Database (Denmark)

    Rasmussen, Lasse Enkebølle; Viberg, Bjarke L; Pottegård, Anton

    2015-01-01

    An 82-year-old woman in treatment with the thrombin inhibitor dabigatran etexilate (a new oral anticoagulant (NOAC)) was admitted with a subtrochanteric femoral fracture and surgery was initiated 15 hours after admittance. She had a blood loss of 6,000 ml and died the next morning from multi......-organ failure. In 2013 1.8% of hip fracture patients in Funen received NOACs. Surgery is recommended within 24 hours for hip fracture patients to reduce mortality, but patients in treatment with NOACs should wait at least 48 hours before major surgery. Care should be taken when prescribing NOACs to patients...

  19. En krobjektiv lidelse? Forståelse og behandling af kroniske, diffuse smertelidelser med fibromyalgi som eksempel

    Directory of Open Access Journals (Sweden)

    Rie Lykke Danielsen

    2011-12-01

    Full Text Available The article deals with the disease field chronic diffuse pains, here exemplified by fibromyalgia, where patients are frequently rendered homeless in an objectivity focused medical treatment system, whose specialities (ideally seen are mutually exclusive, and where the absence of a diagnosis therefore poses a fundamental problem. In the treatment field there is, however, also a bio-psycho-social approach, and these two treatment regimes are respectively termed as a chrObjective approach and a holistic subject approach.By empirical examples, from stories by both therapists and patients, the article describes how the actors navigate between the two treatment regimes, to which the patients must necessarily adapt in their wish for acceptance and assistance from both sides. The authors further discuss to which degree the two treatment regimes are actually incompatible. The interviews and observation of participants, which constitute the empirical basis for the article, were carried out among therapists and patients in Denmark in 2010.

  20. Angiotensin I konverteringshaemmeren enalapril til behandling af progredierende kronisk nefropati. En åben randomiseret kontrolleret undersøgelse

    DEFF Research Database (Denmark)

    Kamper, A L; Strandgaard, S; Leyssac, P P

    1993-01-01

    In order to study the influence of angiotensin converting enzyme (ACE) inhibition on the progression of chronic nephropathy, 70 patients with a median glomerular filtration rate (GFR) of 15 (range, 6 to 54) mL/min/1.73 m2 were randomised in an open study to basic treatment with enalapril...... or conventional antihypertensive treatment. The patients were followed for at least two years or until they needed dialysis. The therapeutic goal, was a blood pressure of 120 ti 140/80 to 90 mmHg. In the enalapril group, the median decline in GFR was -0.20 (range, +0.18 to -7.11) mL/min/1.73 m2/month...

  1. Indacaterol er en én gang dagligt inhaleret β 2-agonist til behandling af kronisk obstruktiv lungesygdom

    DEFF Research Database (Denmark)

    Ulrik, Charlotte Suppli

    2010-01-01

    The aim of pharmacological treatment of COPD is best possible disease control. Bronchodilators are accepted as the mainstay of COPD therapy. This short review focuses on the available data on indacaterol - a new once-daily beta2-agonist. The analysed studies show that indacaterol has clinically i...

  2. Behandling med duodenal-jejunal bypass-sleeve ved svær overvægt

    DEFF Research Database (Denmark)

    Rohde, Ulrich; Gylvin, Silas; Vilmann, Peter;

    2014-01-01

    Overweight and obesity are risk factors for several co-morbidities reducing life expectancy. Conservative treatment of obesity is generally ineffective in the long-term. Bariatric surgery has proven effective, but is associated with potential complications. Duodenal-jejunal bypass sleeve is a novel...

  3. Cadmium in willow plantations - municipal waste products as fertilizers; Kadmiumhalt i Salixodlingar efter behandling med kommunala restprodukter

    Energy Technology Data Exchange (ETDEWEB)

    Hasselgren, K. [ENVIRO Miljoekonsult (Sweden)

    1995-07-01

    Plantations of willows (i.e. Salix spp) seem to absorb cadmium (Cd) from arable land to a greater extent than other plant cultivations. Thus, energy forestry, based upon cultivation of Salix, could possibly be used for biofuel production in combination with biological purification of arable land contaminated with Cd by atmospheric deposition and P fertilizers during the passed 100 years. Application of sewage sludge (5-7 ppm Cd of dry solids) up to 550 g Cd per hectare, or 140 g Cd hectare and year, resulted in clearly increased concentrations of Cd in the upper 10 cm layer of the soil. In deeper soil layers the differences compared with control plots were small. Lower rates of sludge application, corresponding to less than 70 g added per hectare and year, did not materially affect the Cd-content in the soil irrespective of layer. A general pattern was that the content of Cd in plant tissues decreased with increased stem diameter, increased age of stems and stands as well as increased biomass growth. Thus, concentrations of Cd in Salix material, in clones from some of the first generation of energy forest plants (S. viminalis, S. dasyclados and S. schwerinii). were fairly high in young stands. In general, 1-year-old shoots contained 5-6 ppm Cd of dry solids in stems and 10-15 ppm in leaves. In older shoots, up to three years, and older stands, up to six years, the Cd contents decreased to 1-2 ppm Cd and 2-4 ppm Cd of dry solids for stems and leaves, respectively. Abundant supplies of water and nutrients seem to stimulate the Cd uptake in Salix in terms of higher concentrations in plant tissues as well as higher plant growth levels compared with conventional energy forestry. Stands with older stems, not irrigated and not fully fertilized resulted in uptake rates in the range of 10-30 g Cd per hectare and year. 14 refs, 9 figs, 1 tab

  4. Antihypertensiv behandling efter apopleksi--beskyttende effekter mod kardiovaskulaer sygdom ud over det, som opnås ved blodtryksreduktionen?

    DEFF Research Database (Denmark)

    Christensen, Kent Lodberg; Husted, Steen

    2006-01-01

    The presence of significant effects beyond what may be achieved by reducing consultation blood pressure, particularly in stroke prevention, has been indicated by several clinical hypertension trials, including LIFE, ASCOT, NORDIL, ACCESS and now also MOSES. New data suggest that apparent pressure...... equality could be a beta-blocker-induced diminished white coat effect; despite this, the evidence points towards the presence, however not a major one, of meaningful preventive effects unrelated to pressure reduction. Udgivelsesdato: 2006-May-29...

  5. Præhospital behandling ved større udendørs musikfestival. Økonomiske aspekter

    DEFF Research Database (Denmark)

    Mikkelsen, J B; Larsen, C F

    1994-01-01

    An emergency facility was provided at the Midtfyn Rock Music Festival in 1990 (comprising 7,000 musicians and ancillaries and an overall public attendance of 60,000). A total of 329 patients were treated at the facility during the four and a half days that the festival lasted. The numbers...

  6. Forskelle på ordinationsmønstret af analgetika ved behandling af cancersmerter på seks danske smertebehandlingsenheder

    DEFF Research Database (Denmark)

    Olesen, Anne Estrup; Jarvig, Line; Hansen, Ole Bo;

    2007-01-01

    analgesics were prescribed for 40% of the patients while 50% of the patients were treated with paracetamol and/or NSAID. According to the medical records 79% of the patients were prescribed analgesics for breakthrough pain. 73% of the 347 patients had strong opioids prescribed for breakthrough pain....... For the treatment of background pain opioids were prescribed for the majority of the cancer patients. Morphine and oxycodone were prescribed most frequently. Secondary analgesics and paracetamol and/or NSAID were also prescribed for background pain. The strong opioids were prescribed for the treatment...

  7. Udvikling af cerebrale infarkter hos en 17-årig mand i behandling med sertralin og lisdexamfetamin

    DEFF Research Database (Denmark)

    Martinussen, Malene; Debes, Nanette Mol; Christensen, Catrine;

    2016-01-01

    A 17-year-old male with ADHD who was treated with sertraline and lisdexamfetamine presented with transient episodes of speech impairment and right-sided hemiparesis preceded by headaches. Magnetic resonance imaging revealed three cerebral ischaemic lesions. Treatment was initiated with aspirin an...... be ruled out as risk factors.......A 17-year-old male with ADHD who was treated with sertraline and lisdexamfetamine presented with transient episodes of speech impairment and right-sided hemiparesis preceded by headaches. Magnetic resonance imaging revealed three cerebral ischaemic lesions. Treatment was initiated with aspirin...

  8. Forebyggelse af infektioner hos patienter, der har kronisk inflammatorisk tarmsygdom og er i behandling med TNF-hæmmere

    DEFF Research Database (Denmark)

    Risager Christensen, Katrine; Steenholdt, Casper

    2014-01-01

    suppression of the immune system. National and international guidelines recommend screening and vaccination for selected infectious agents prior to anti-TNF initiation as well as during ongoing anti-TNF therapy. This review focuses on current available recommendations and discusses physicians’ and patients...

  9. Treatment of biofuel ashes for forest recycling; Behandling av aska fraan biobraenslen foer spridning paa skogsmark - etapp 1

    Energy Technology Data Exchange (ETDEWEB)

    Bjurstroem, H.; Sjoeblom, R. [AaF-Energikonsult, Stockholm (Sweden)

    1997-03-01

    Logging residues are the easiest available fuel for an increased production of energy in Sweden from renewable sources. A consequence of their removal from the forest is that the cycle of mineral nutrients is broken. The purpose of recycling the ash after this fuel to forest land is to compensate for the removal and close again the nutrient cycle. Recycling nutrients and returning the inorganic components of the biomass removed from the forest should be performed in accordance with general principles of environmental protection, health considerations and the good house-keeping of natural resources. The activities should also be carried out in accordance with the needs of the forest and energy plant owners regarding good technology and economy. This implies that functional requirements originating from these principles and needs should be clearly structured and formulated and that such requirements should provide a basis for the continued development work as well as for the implementation of suitable, economical and efficient systems. Returning inorganic constituents implies that the principle of recirculation is followed as well as that nutrients are brought back which improves accretion in the forest. At the same time, the risk of damage to the forest can be assessed as insignificant. Furthermore the risks to human health are also assessed to be insignificant provided that pertinent precautions are taken to avoid dusting. In the present report, technical and economical aspects of importance for the selection of method as well as for the establishment of a system are described and discussed. The need for further development work is identified in the following areas: functional requirements - operational requirements, sampling, testing and quality assurance, granulation, curing processes and drying/sintering. 102 refs, 1 fig, 2 tabs

  10. Behandling af reumatoid artrit med anti-tumornekrosefaktor-alpha-antistof. Individuel monitorering af biotilgaengelighed og immunogenicitet-- sekundaerpublikation

    DEFF Research Database (Denmark)

    Bendtzen, Klaus; Geborek, Pierre; Svenson, Morten

    2007-01-01

    Remicade/infliximab is effective in rheumatoid arthritis (RA), but response failure is frequent. Sera from 106 RA patients were monitored using an RIA for functional infliximab and an RIA for anti-infliximab antibody (Ab). S-infliximab varied considerably, e.g. 0-22 microg/ml before the 3rd...... infusion, and 44% were Ab-positive after 6 months. Low s-infliximab was associated with Ab development and later therapeutic failure, and high Ab levels could be related to dose increases, side-effects and cessation of therapy. Pharmacological monitoring should help optimize anti-TNF therapies....

  11. Skandinaviske kliniske retningslinjer for præhospital behandling af patienter med svære hovedtraumer

    DEFF Research Database (Denmark)

    Juul, Niels; Sollid, Snorre; Sundstrøm, Terje;

    2008-01-01

    Head trauma causes the death of many young persons. The number of fatalities can be reduced through systematic management. Preventing secondary brain injury together with the fastest possible transport to a neurosurgical unit has been shown to be effective in reducing mortality and morbidity...

  12. Behandling af våd aldersrelateret makuladegeneration med vaskulaer endotel vaekstfaktorhaemmer. Gennemgang af et Cochrane-review

    DEFF Research Database (Denmark)

    Bloch, Sara Brandi; Larsen, Michael

    2009-01-01

    a direct comparison or an indirect statistical comparison between the two antiangiogenic agents. In clinical practice ranibizumab compared to pegaptanib is the drug of choice because of cost-utility analysis and the number of patients gaining visual acuity. Udgivelsesdato: 2009-Nov......This evaluation of a Cochrane-review including five clinical trials of good methodological quality indicates that the antiangiogenic therapeutic agents, pegaptanib and ranibizumab, are effective treatment strategies for neovascular Age-Related Macular Degeneration (AMD). The review does not include...

  13. Cancer i øjenregionen

    DEFF Research Database (Denmark)

    Prause, J.U.; Heegaard, S.; Toft, Peter Bjerre

    2002-01-01

    oftalmologi, cancer, tumor, øjenlåg, conjunctiva, cornea, hud, øjets indre, orbita, diagnostik, behandling......oftalmologi, cancer, tumor, øjenlåg, conjunctiva, cornea, hud, øjets indre, orbita, diagnostik, behandling...

  14. At udholde forandringer i hverdagslivet – patienters oplevelse af at være i behandling for endetarmskræft

    DEFF Research Database (Denmark)

    Hansen, Birgitte Knygle; Winther, Bodil; Norlyk, Annelise

    2015-01-01

    treatment for colonic cancer. Ten patients participated in the study. Data were collected through semi-structured interviews and analysed using the guidelines for meaning interpretation given by Kvale and Brinkmann. The analysis led to one dominating theme: endurance and four subthemes: coping with bodily...

  15. Outlet of products of biological treatment- what will be the future problems and opportunities?; Avsaettning av energiprodukter fraan biologisk behandling - vilka fraagestaellningar kommer att bli aktuella?

    Energy Technology Data Exchange (ETDEWEB)

    Hellstroem, Hanna

    2010-01-15

    Biological treatment and related products is a topical subject, which increases year after year, not only in Sweden but all over the world. In this phase of expansion, it is interesting to find out what subjects could become relevant for products from this treatment method in the future. The following products are incorporated in the concept 'energy products' from biological treatment: sludge from sewage treatment plants, digestate from waste digestion plants, biogas, ethanol, and products from biorefinery. Questions regarding the process of these products are not included in this project. The purpose is to bring forward a catalogue of ideas of current and future topics in the field of biological treatment. The goal is to identify development projects which could be of interest for upcoming programs at Waste Refinery. Issues and project proposals for each product have been identified by the writer's network, and in discussions tabled at a workshop arranged by Waste Refinery in the autumn of 2009. At the present time, almost all digestate is sold, but there are problems. Though the plants have found an outlet for their products, they do not receive adequate return on them. Moreover, a lot of water is being transported. Many stakeholders within Waste Refinery, as well as external stakeholders, have requested a project on refining of digestate. Other topical issues regarding digestate are how new, non-food substrates and additives affect the quality of the digestate. Sewage treatment plants have to pay large amounts of money for the disposal of sludge. If Waste Refinery can include sewage sludge in their range of work, there will be several synergies between sludge and digestate. Matters, that need to be solved in the near future, are how to best achieve hygienisation of sewage sludge in order to guarantee salmonella-free sludge. As for biogas, the demand will be determined by factors such as the access of raw material, whether it becomes a vehicle fuel to count on in the future, taxes and means of control (i.e. environmental objectives). Concrete project proposals regarding the gas composition and measurement of raw gas, as well as the minimization of emissions have been received. There are also many questions regarding the distribution of biogas. As for ethanol, the questions primarily regard the process and new substrates identified in interesting fields. Such matters and project ideas have, however, not been considered, as this report is intended to identify questions about the products. Contact with various ethanol producers and researchers has shown that there is, as it seems, no need for further development of ethanol as a product. Waste Refinery has already touched the subject of biorefinery in the WR 20 project, refinement of digestion residue. No project proposals have been identified for products from biorefinery, either by the writer's network or during the workshop. One proposal is to do a more thorough study of biorefinery under the management of Waste Refinery

  16. Perforation of the colon during combined radio and steroid therapy. Diagnosis and treatment; Colonperforsjon under kombinert steroid- og straalebehandling. Diganostikk og behandling

    Energy Technology Data Exchange (ETDEWEB)

    Wiig, J.N.; Aass, N.; Karlsen, K.O.; Giercksky, K.E. [Norske Radiumhospital, Oslo (Norway)

    1996-02-01

    Eighth patients with colon perforations after combined treatment with radiotherapy and steroid medication are studied retrospectively. Sigmoid diverticuli perforated after a minimum of 5 days treatment. The main symptom was a varying degree of abdominal pain. Clinical parameters were of limited value. The most important single examination was plain abdominal x-ray, though this was not positive in all cases. Seven patients were operated on, one with simple suture, the rest with Hartmann`s procedure. None developed postoperative peritonitis. One died from cerebral infarction. Four died within 38 days postoperatively after discharge from hospital. Abdominal symptoms during high dose steroid treatment may indicate perforation on the colon. Immediate operative intervention may have an uncomplicated postoperative course. 8 refs., 2 tabs.

  17. Der er begrænset effekt af interferonbeta til behandling af sekundær progressiv multipel sklerose--en gennemgang af et Cochranereview

    DEFF Research Database (Denmark)

    Schreiber, Karen; Voldsgaard, Ana; Sørensen, Per Soelberg

    2013-01-01

    Interferon (IFN)-beta 1b is approved for the treatment of secondary progressive multiple sclerosis (SPMS) with relapses in the EU. This Cochrane review analysed all double- or single-blinded randomised placebo controlled studies that had evaluated the efficacy of IFN-beta versus placebo in SPMS...

  18. Patienter med basalcellenævussyndrom bør tilbydes tidlig interdisciplinær opfølgning og behandling

    DEFF Research Database (Denmark)

    Bay, Christiane; Ousager, Lilian Bomme; Jelsig, Anne Marie

    2016-01-01

    Basal cell naevus syndrome (Gorlin-Goltz syndrome) is a rare, autosomal dominantly inherited condition with a wide range of developmental and multiple organ-related anomalies. Cardinal features include multiple basal cell carcinomas, jaw cysts, palmoplantar pits and calcification of the falx...

  19. Handling of safety issues in the senior management group at the nuclear power plants; Behandling av saekerhetsrelaterade fraagor i kaernkraftverkens ledningsgrupper

    Energy Technology Data Exchange (ETDEWEB)

    Wahlstroem, B. [VTT Automation, Esbo (Finland)

    2001-02-01

    The report describes the results from a series of interviews, which were made in the preparation of an application for a reserach project to the Nuclear Fission Safety Programme of EU. The project application 'Learning organisations for nuclear safety - LearnSafe' collected a consortium of 5 partners and 9 associated partneres and has been assigned the reference number FIS5-2001-00066 by the European Commission. (au)

  20. OPUS: Randomiseret multicenterundersøgelse af integreret behandling sammenlignet med standardbehandling før første psykoseepisode--sekundaerpublikation

    DEFF Research Database (Denmark)

    Nordentoft, Merete; Petersen, Lone; Jeppesen, Pia;

    2006-01-01

    A total of 547 patients with first-episode psychosis were included in a randomised clinical trial comparing integrated treatment with standard treatment. The integrated treatment consisted of assertive community treatment with programmes for family involvement and social skills training. Patients...

  1. Mænd med rejsningsbesvær efter radikal prostatektomi bør behandles efter sædvanlige retningslinjer

    DEFF Research Database (Denmark)

    Fode, Mikkel; Hansen, Rikke Bølling; Maigaard, Thomas

    2015-01-01

    . The method is effective in animal models, but the results cannot be confirmed in humans. At this time, treatment regimens which actually create erections and allow for sexual intercourse following surgery should be prescribed. These include PDE5 inhibitors, vacuum erection devices, injection therapy...

  2. Mænd med rejsningsbesvær efter radikal prostatektomi bør behandles efter sædvanlige retningslinjer

    DEFF Research Database (Denmark)

    Fode, Mikkel; Hansen, Rikke Bølling; Maigaard, Thomas

    2014-01-01

    . The method is effective in animal models, but the results cannot be confirmed in humans. At this time, treatment regimens which actually create erections and allow for sexual intercourse following surgery should be prescribed. These include PDE5 inhibitors, vacuum erection devices, injection therapy...

  3. Fysisk traening som behandling af nedsat funktionsevne hos svage, hjemmeboende 75+ -årige. Et randomiseret interventionsstudie i almen praksis omfattende elementer til en teknologivurdering

    DEFF Research Database (Denmark)

    Vad, Esther; Worm, Charlotte; Lauritsen, Jens;

    2002-01-01

    The aim of this study was to establish the value of physical training as a treatment of reduced physical ability in frail, elderly patients living at home.......The aim of this study was to establish the value of physical training as a treatment of reduced physical ability in frail, elderly patients living at home....

  4. Præhospital behandling af svært tilskadekomne patienter med fokus på damage control-kirurgi

    DEFF Research Database (Denmark)

    Sørensen, Anne Marie; Larsen, Claus Falck; Steinmetz, Jacob

    2011-01-01

    The majority of patients undergoing damage control surgery initially receive prehospital treatment. Bleeding causes 40% of trauma deaths, half of which happen in the prehospital setting. Future research and improved treatment before hospital admission should focus on control of the bleeding, avoi...

  5. Kontrollmestringsteori og Becks kognitve teori. En sammenlignende undersøkelse av teoriene med henblikk på forståelse og behandling av depresjon

    OpenAIRE

    Brabrand, Kristin; Søvik, Ellen; Blomdal, Ane Jostedt

    2012-01-01

    Psychotherapy theories differ in how they understand and approach depression (Nordahl et al., 2012). In this paper we compare the control-mastery theory and Beck`s cognitive theory, with the aim to identify similarities and differences between the theories. In this comparison, similarities in conceptualization appeared. Both the control- mastery theory and Beck`s cognitive theory describe depression as developed on the basis of maladaptive cognitions (Beck, 1970; Weiss, 1993). At the same tim...

  6. Kirurgisk behandling af cancer ventriculi på et universitetshospital. En retrospektiv opgørelse for perioden 1990-1995

    DEFF Research Database (Denmark)

    Hillingsø, Jens; Hviid, Kirsten; Mynster, T;

    2001-01-01

    AIM: A retrospective study of 69 cases of gastric cancer seen during the period from 1/1-1990 to 31/12-1994 treated in a University Hospital. The aim of the study was to describe morbidity, mortality and identify independent prognostic variables for mortality. METHOD: Patient data were recovered.......001) as independent variables. DISCUSSION: The overall five-year survival is low and has not changed over two decades in Denmark, whereas mortality and morbidity rates have improved. It should be recommended that: The treatment of gastric cancer must be centralised in order to develop preoperative examinations...... from the hospital's central database. Mortality was chosen as end-parameter. Univariate log-rank-test identified statistically significant variables which were then analysed by Cox backward stepwise regressional analysis. MATERIAL: Sixty-nine patients were available for analysis, median age 73 years...

  7. Assisteret hjemmebehandling af eksacerbation i kronisk obstruktiv lungesygdom. Fremskyndet udskrivelse til fortsat behandling, monitorering og pleje i eget hjem varetaget af lungesygeplejerske

    DEFF Research Database (Denmark)

    Ringbaek, Thomas Jørgen; Eriksen, Nanna; Vestbo, Jørgen

    2003-01-01

    of COPD. In order to evaluate various types of assisted home care, the selection of patients, feasibility, effect, safety, and cost-effectiveness, the literature was reviewed. Most information is available on assisted home care following a hospital-based assessment and led by a respiratory nurse......Chronic obstructive pulmonary disease (COPD) is a leading cause of hospitalisation in Danish adults, and admission rates are expected to increase in the future. Assisted home care with disease monitoring and treatment by a pulmonary nurse may reduce time spent at hospital and the economic burden...

  8. Træning har positiv effekt på helbredsrelateret livskvalitet hos kræftpatienter i behandling--en gennemgang af et Cochranereview

    DEFF Research Database (Denmark)

    Lønkvist, Camilla Kjær; Højman, Pernille; Gehl, Julie;

    2013-01-01

    and reduces risk of recurrence and mortality from breast- and colon cancer. Considerable efforts go to patient care and rehabilitation, both during and after cancer treatment. This new systematic review implies that exercise programmes should be a central part of rehabilitation for all cancer patients.......Cancer and treatment of cancer affects the health-related quality of life (HRQoL) in patients. A recent Cochrane review concludes that exercise may have positive effects on HRQoL and several other domains. Other reviews have shown that physical activity may protect against development of cancer...

  9. Behandling af defaekationsblokade som følge af dyb fossa recto-genitalis med total baekkenbundsrekonstruktion med Prolene-net

    DEFF Research Database (Denmark)

    Møller, P; Monrad, H; Kehlet, H

    1992-01-01

    of the abdominal pain and dependence on morphine in two of the patients. Rectal compression resulting from an abnormally deep recto-genital fossa should be included in the differential diagnostic deliberations in patients with severe constipation and defaecation blockage. Complete reconstruction of the pelvic......The causes of severe defaecation blockage resulting from compression of the rectum and deep recto-genital fossa are reviewed and are illustrated by three patients who had previously undergone hysterectomy and who had incapacitating defaecation blockage and abdominal pain requiring morphine in two...... of the patients. The condition had not been diagnosed despite previous hospital contact for many years in two of the patients. Complete reconstruction of the pelvic floor with prolene net was performed. Subsequent defaecography showed normalization of defaecation without rectal compression and with relief...

  10. Stress i gymnasiet - Hvad der stresser gymnasielever og hvordan forebyggelse og behandling virker med ’Åben og Rolig for Unge’

    DEFF Research Database (Denmark)

    Nielsen, Anne Maj; Lagermann, Laila Colding

    Denne undersøgelse af stress hos gymnasieelever i Aalborg viser, hvordan stress giver sig udslag i gymnasiet, hvad der stresser eleverne, hvad der adskiller de stressramte elever fra andre elever, hvordan et stressreduktionskurset Åben og Rolig for Unge virker for de unge i gymnasiet, og hvad der...

  11. Rusmisbruk, angst og depresjon etter 10 år: En prospektiv undersøkelse av stoffmisbrukere med og uten LAR-behandling

    Directory of Open Access Journals (Sweden)

    Ravndal Edle

    2015-12-01

    Full Text Available Substance abuse, anxiety and depression after 10 years: A prospective study of drug users in and outside OMT treatment AIMS - The national Opiate Maintenance Treatment (OMT program in Norway started officially in 1998. The same year a treatment study was initiated, including the most used treatment measures for drug users in Norway. The main aim in the present study was to investigate the prevalence of live OMT patients in the total sample after 10 years, and to compare the outcome of primarily substance abuse, anxiety and depression among OMT patients versus non-OMT patients. DESIGN & METHODS - Four hundred and seven patients, in Oslo and the nearby regions, who started in 16 different in- and outpatients programs, were followed from intake to treatment and during ten years (1998-2009. Patients in the sample were interviewed after one, two, seven and ten years, and they were divided into three different treatment groups: inpatient residency for grown-ups, outpatient psychiatric youth teams and youths living in collectives. Data was collected through use of EuropASI and HSCL-25 at all follow-ups. RESULTS - After ten years 15 % were deceased. Of the 333 persons left, 73 % (n=248 were interviewed after ten years. Forty percent (n=99 were then in OMT. After ten years there were no gender differences regarding attendance to OMT, but the OMT-group was older (30 vs .28 yrs, p<0.05, and they used more benzodiazepines (p<0.000 and cannabis (p<0.01 than the others. The OMT-group reported to a larger extent more anxiety and depression throughout the total observation period than the non OMT participants. Use of heroin and criminality were significantly reduced in both groups. CONCLUSIONS - In spite of reduced use of heroin, the OMT patients seemed to have more difficulties in reducing the use of benzodiazepines and cannabis, whereas the anxiety and depression scores were high and stable through the total observation time.

  12. Fluconazol og amning

    DEFF Research Database (Denmark)

    Pedersen, Andreas James Thestrup; Hessellund, Anne; Bergmann, Troels Korshøj;

    2016-01-01

    Når lokalbehandling til candidainfektion ikke er nok, er næste valg systemisk behandling. Men hvad, hvis kvinden ammer? Kan systemisk behandling med tablet fluconazol anvendes? Svaret er ja – men langvarig behandling (> 2 uger) bør undgås. Fluconazol vil udskilles i brystmælk, men mængden af...... fluconazol, som barnet derved indtager, er lav....

  13. Prognosis of organic sugar cane spirit production in the Araras region / Prognose da produção de cachaça orgânica na região de Araras

    Directory of Open Access Journals (Sweden)

    Davi Guilherme Gaspar Ruas

    2009-03-01

    Full Text Available In spite of social and economic value of the Brazilian sugar cane spirit or cachaça, there are few studies about the parameters of agroindustrial of sugar cane and the profile of the producers, along with concern for quality. This agro-industry has significant number of small producers with it’s activity one way to obtain an income, bringing employments and foreign exchange to the country. However, these producers manufacture empirical and rudimental way, based on common sense or information by father or son. The aim of the study was to characterize the profile of the producers of sugar cane spirit or cachaça of the region of Araras, linked them to the viability of obtaining a products of high quality using organic methods. As result of this study was evidenced that the region of Araras shows the same characteristic profile of this sector, where a large majority work in informal conditions, without certificate on Agriculture Ministry and sell its production in local markets. The conditions of manufacturing juice of sugar cane are very rudimentary, where a large majority of producers with simple distillations apparatus. Relatively to the possibility of production of organic sugar cane spirit or cachaça, the main difficulty is located on the rural area, caused by the strong dependence on soluble chemical fertilizers. The production of organic sugar cane spirit or organic cachaça would be one alternative sufficient practicable and attractiveApesar da importância econômica e social da aguardente de cana-de-açúcar ou cachaça, são escassos os trabalhos encontrados na literatura que estabelecem comparações entre as características agroindustriais da cultura e o perfil do produtor, aliado à preocupação com a qualidade. Esta agroindústria se caracteriza por apresentar significativa quantidade de pequenos produtores que possuem nesta atividade uma forma de geração de renda, trazendo para o País divisas e empregos. Entretanto, produzem de maneira empírica e rudimentar, baseados no senso comum ou informações repassadas de pai para filho. Foi feito um levantamento preliminar visando caracterizar o perfil das propriedades produtoras de aguardente de cana-de-açúcar da região de Araras, associando-as à viabilidade de obter-se um produto de qualidade com características orgânicas. A região de Araras apresenta um perfil característico do setor, onde a grande maioria trabalha na informalidade, sem registro no Ministério da Agricultura e comercializa sua produção no local. As condições de processamento da cana-de-açúcar são rudimentares e a maioria dos produtores utiliza o fogo direto no alambique, usando lenha como combustível. Em relação a uma possível produção de cachaça orgânica a principal dificuldade está no setor agrícola, devido à forte dependência do uso de adubos químicos solúveis e herbicidas. A produção de cachaça orgânica pode ser uma alternativa viável e atrativa.

  14. Microscopic Invasions, Prognoses, and Recurrence Patterns of Stage I Adenocarcinomas Manifesting as Part-Solid Ground-Glass Nodules: Comparison With Adenocarcinomas Appearing as Solid Nodules After Matching Their Solid Parts' Size.

    Science.gov (United States)

    Hwang, Eui Jin; Park, Chang Min; Kim, Young Tae; Kim, Hyungjin; Goo, Jin Mo

    2016-04-01

    The purpose of the present study was to compare the frequency of microscopic invasions, disease-free-survival (DFS), and the frequency and pattern of disease recurrence between stage I pulmonary adenocarcinomas appearing as solid nodules and those appearing as part-solid ground-glass nodules (GGNs) after matching their solid parts' size (D(solid)) and patients' age. Among 501 patients who underwent curative surgery for stage I pulmonary adenocarcinomas between 2003 and 2011, 172 patients (86 with solid nodules [M: F = 36: 50; mean age, 62.8 years] and 86 with part-solid GGNs [M:F = 30:56; mean age, 63.0 years]) matched for D(solid) and patients' age were included. DFS, frequency of microscopic invasions, recurrence, and recurrence pattern were compared between the two groups. No significant difference was observed in the frequency of microscopic invasions between the two groups (visceral pleural invasion, 30.23% vs. 29.07%, P = 0.867; lymphatic invasion, 5.81% vs. 3.49%, P = 0.720; vascular invasion, 1.16% vs. 0%, P = 1.000; solid nodules vs. part-slid GGNs, respectively) and DFS (estimated 5-year DFS, 83.6% vs. 81.9%, P = 0.744; solid nodules vs. part-slid GGNs, respectively). As for recurrence and recurrence pattern, there were no significant differences between the solid nodule group (14/86), and part-solid GGN group (12/86) (P = 0.670). Lung parenchymal nodules were the most frequent pattern of disease recurrence in both groups, followed by pleural seeding. In conclusion, after matching D(solid) and patients' age, there was no significant difference in the frequency of microscopic invasions, DFS, and the frequency and pattern of recurrence between stage I pulmonary adenocarcinomas appearing as solid nodules and part-solid GGNs.

  15. Project 'WINDBANK mittleres Aaretal' - Analysis, Diagnosis and Forecast of Wind Fields around the Nuclear Power Plant Goesgen; Projekt 'WINDBANK mittleres Aaretal' - Analyse, Diagnose und Prognose der Windverhaeltnisse um das Kernkraftwerk Goesgen

    Energy Technology Data Exchange (ETDEWEB)

    Graber, W.K.; Tinguely, M

    2002-07-01

    An emergency decision support system for accidental releases of radioactivity into the atmosphere providing regional wind field information is presented. This system is based on intensive meteorological field campaigns each lasting 3-4 months in the regions around the Swiss nuclear power plants. The wind data from temporary and permanent stations are analysed to evaluate the typical wind field patterns occurring in these regions. A cluster analysis for these data-sets lead to 12 different wind field classes with a high separation quality. In the present report, it is demonstrated that an on-line acquisition of meteorological data from existing permanent stations is enough to diagnose the recent wind field class in a region with a radius of 25 km around the nuclear power station of Goesgen with a probability of 95% to hit the correct class. Furthermore, a method is presented to use a high resolution weather prediction model to forecast the future wind field classes. An average probability of 76% to hit the correct class for a forecast time of 24 hours is evaluated. Finally, a method for parameterization of turbulence providing input for dispersion models from standard meteorological online data is presented. (author)

  16. KLINO - climatology and prognosis of climate-induced changes in hydrographic parameters of the North Sea and Baltic Sea. Final report; KLINO - Klimatologie und Prognose klimainduzierter Aenderungen hydrographischer Groessen in Nord- und Ostsee. Abschlussbericht

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2000-04-01

    The marine climate of the North Sea and Baltic Sea was simulated and analyzed with the aid of meteorological and oceanographic models. The KLINO project is a first step towards climate impact research as sensitivity studies of the models permit preliminary statements on the effects of potential changes of marine climate. The simulations covered several decades. The models used were: WAM for calculating the swell of the Atlantic and the two marginal seas; HAMSOM for climate-induced variations of the hydrographic parameters of the NOrth Sea and Baltic Sea; HAMSOM and REMO for interactive coupling between ocean and atmosphere; HYDROMOD for extreme and normal conditions in the offshore region. [German] Im Projekt KLINO wurde das derzeitige marine Klima (Wasserstaende und mittlerer Meeresspiegel, Seegang, Stroemungen und Schichtung) von Nord- und Ostsee in Kontrollexperimenten mit Hilfe meteorologischer und ozeanographischer Modelle simuliert und nach vollzogen. Das KLINO Projekt ist in die Arbeiten zur Klima-Regionalisierung bzw. als ein erster Schritt zur Klima-Impaktforschung einzustufen, da Sensitivitaetsstudien der Modelle bereits vorsichtige Aussagen ueber die Folgen moeglicher Aenderungen des marinen Klimas zulassen. Das WAM-Modell lieferte eine Klimatologie des Seeganges fuer den Atlantik und die beiden Randmeere. Die klimainduzierten Schwankungen der hydrographischen Parameter in Nord- und Ostsee wurden mit Hilfe des HAMSOM untersucht; eine interaktive Kopplung zwischen Ozean und Atmosphaere erfolgte mit den Regionalmodellen HAMSOM und REMO. Die Simulationen deckten hinreichend lange Zeitraeume (Dekaden) ab und wurden mit beobachteten bzw. aus meteorologischen Re-Analysen abgeleiteten Fluessen von Impuls, Waerme und Frischwasser angetrieben. Zur Initialisierung und Validierung der ozeanographischen Modelle wurden umfangreiche Beobachtungsdatensaetze fuer die Parameter Temperatur, Salzgehalt, Eis, Seegang und Oberflaechenauslenkung zusammengestellt. Extremsituationen und mittlere Verhaeltnisse im Kuestenbereich wurden exemplarisch fuer zwei Untersuchungsgebiete mit dem HYDROMOD-Modell untersucht. Impaktstudien zu den Auswirkungen einer intensivierten nordatlantischen Oszillation, die in KLINO durchgefuehrt wurden erlaubten erste Aussagen ueber die Folgen moeglicher Aenderungen des Klimas auf der Regionalskala. (orig.)

  17. Inventory evaluation and prognosis of NORM residues for the final disposal in a radioactive waste final repository. Final report; Bestandsaufnahme und Prognose von NORM-Rueckstaenden fuer die Endlagerung in einem Endlager fuer radioaktive Abfaelle. Abschlussbericht

    Energy Technology Data Exchange (ETDEWEB)

    Ettenhuber, E.; Gellermann, R.; Kahnwald, S.; Kunze, C.; Weiss, D.; Schulz, H.

    2014-11-15

    The report on the evaluation and prognosis of NORM residues for the final disposal covers the following issues: scope of the project; practice of release of NORM residues for utilization and disposal and its impact on the mass balance of NORM wastes; compilation of the amount of NORM residues with improbable clearance from radiation protection monitoring; identification of so far existing storage sites and interim storage possibilities and their capacities; NORM residues that are not released from radiation surveillance and need presumably the delivering to a radioactive waste repository; estimation of cost and evaluation of economic aspects for the options interim storage and final disposal; options for the final disposal of NORM wastes.

  18. The value of measurements of the cerebrovascular reserve capacity (CVRC) for the assessment and prognosis of cerebrovascular disease; Der Stellenwert der Messung der zerebrovaskulaeren Reservekapazitaet bei der Beurteilung und Prognose ischaemischer Hirnerkrankungen

    Energy Technology Data Exchange (ETDEWEB)

    Einhaeupl, K.M. [Klinik und Poliklinik fuer Neurologie, Universitaetsklinikum Charite, Medizinische Fakultaet der Humboldt-Universitaet, Berlin (Germany); Valdueza, J.M. [Klinik und Poliklinik fuer Neurologie, Universitaetsklinikum Charite, Medizinische Fakultaet der Humboldt-Universitaet, Berlin (Germany)

    1997-03-01

    Today, the diagnostic and therapeutic principles in the management of stroke are changing. Prevention of stroke is one of the major fields of research. One important aim of the newly developed diagnostic techniques is the identification of a particular subgroup of patients with compromised cerebral circulation who will benefit from surgical or medical therapies. The assessment of the CVRC with tracer techniques and the acetazolamide test seem to be a realiable and promising method for this purpose: 1. In carotid artery occlusion, the measurement of CVRV facilitates the identification of a subgroup of patients with compromised CVRC who show an improvement of CVRC after EC-IC bypass surgery. The value of bypass surgery for the prevention of stroke however, has to be confirmed by prospective studies. 2. The benefit from carotid surgery for patients with high-grade carotid stenosis and transient ischemic attack has been convincingly demonstrated by several studies. In asymptomatic patients, however, desobliteration of the carotid artery remains controversial. The identification of asymptomatic cases with compromised CVRC probably contributes to the recognition of patients with a high risk of suffering hemodynamic stroke. 3. In vascular dementia, cerebral blood flow measurements at rest alone have not been useful. CVRC measurements may offer a diagnostic advance in this still not well understood disease. (orig.) [Deutsch] Die Erkennung von Patientengruppen mit besonderer Schlaganfallgefaehrdung, die von konservativen wie chirurgischen Massnahmen profitieren wuerden, ist von hoechster klinischer Relevanz. Mit der Bestimmung der zerebrovaskulaeren Reservekapazitaet (CVRC) mit Acetazolamid besitzen wir einen funktionellen Parameter der zerebralen Haemodynamik, der eine Risikoabschaetzung bezueglich eines Schlaganfalls fuer folgende Indikationen erwarten laesst: 1. Bei Patienten mit einem Karotisverschluss konnte von verschiedenen Arbeitsgruppen gezeigt werden, dass sich durch eine EC-IC-Bypass-Operation eine zuvor eingeschraenkte CVRV verbessern laesst. Der Nachweis, dass hierdurch das Schlaganfallrisiko vermindert wird, muss jedoch in groesseren prospektiven Studien erbracht werden. 2. Bei der symptomatischen Karotisstenose ist der Nutzen der Desobliteration mittlerweile nachgewiesen worden. Bei der asymoptomatischen Karotisstenose wird die Indikation zur Desobliteration kontrovers diskutiert. Der Nachweis einer eingeschraenkten CVRC koennte, analog zum Karotisverschluss, die Indikation zu einem gefaesschirurgischen Eingriff unterstuetzen. Auch hier sind weitere Studien noetig. 3. Bei der morphologischen und klinischen Zuordnung der vaskulaeren Demenz haben Ruhemessungen des CBF bisher keinen Einfluss gehabt. Es ist zu ueberpruefen, ob fuer dieses Kollektiv zukuenftig die Messung der CVRC einen diagnostischen Fortschritt darstellt. (orig.)

  19. Forecasts and restrictions on vibrations from rock excavation and transportation. Encapsulation Plant and Repository for spent nuclear fuel, Laxemar; Prognoser och restriktioner foer vibrationer fraan bergschaktning och transporter. Inkapslingsanlaeggning och slutfoervar foer anvaent kaernbraensle, Laxemar

    Energy Technology Data Exchange (ETDEWEB)

    Lind, Carl; Johansson, Sven-Erik (Nitro Consult AB (Sweden))

    2010-12-15

    This study describes the impact on the surroundings that may occur during rock excavation activities for the final repository for spent nuclear fuel in Laxemar and the encapsulation facility in Simpevarp. The study also includes vibrations created by heavy shipments related to activities at the final repository. The study will provide input to the environmental impact assessment and future design work. The survey area for buildings and facilities covered by the study extends approximately 1,000 metres from the proposed location of the final repository. For the encapsulation facility the survey area has been limited to residential buildings and summer houses within 1,000 metres of the proposed location. In addition, residential buildings along road 743 have been surveyed with regard to the impact of heavy shipments between Laxemar and Faarbo. The results of the surveys and information on planned rock excavation activities have been used to formulate preliminary restrictions and predictions of vibrations and air shock waves from blasting, as well as noise from rock drilling. Predictions have also been made of vibrations from heavy shipments, and a reference survey has been carried out in a residential building near road 743. The predictions of vibrations from blasting rounds reveal low or very low levels. No risk of damage to buildings or equipment is expected. Vibrations from blasting may, however, be perceptible within large parts of the study area, since the human perception threshold for vibration is very low. They will hardly be regarded as disturbing, however. When the accesses to the final repository have been built and rock excavation continues at repository level, the impact on the surroundings is expected to be minimal. The main reason for this is that the blasting will then occur at a depth of about 500 metres, at an ample distance to buildings at surface level. Predictions of air shock waves from blasting rounds indicate low levels. There is no risk of damage but air shocks may be audible at great distances during the first few years when surface facilities are being built and blasting is being done for the ramp and sunk shafts. They are not expected to be perceived as disturbing, since the blasting will be limited to a few times per day during the most intensive period. Structure-borne noise from rock drilling for the repository will not be audible due to large distances to buildings. Noise from above-ground drilling may be audible, but below guideline values. Also, the drilling is limited to a relatively short period of time. In Clab, indoor guideline values may be exceeded during drilling for the encapsulation facility. There is no risk of flyrock from blasting that could cause damage to the surroundings. The scope and nature of flyrock protection will be determined at a later stage, but as a general rule the initial blasting rounds, when the risk of flyrock is the greatest, will be carried out as controlled blasting. Vibrations in surrounding buildings caused by heavy shipments to and from the final repository are not expected to cause any damage, mainly due to the fact that the supporting ground along the transport routes is dominated by rock or till. The reference survey carried out in Oevrahammar verifies this and shows low vibration levels. If the future status of the concerned parts of road 743 is the same as today, disturbing vibrations are unlikely to occur, even if the heavy shipments increase in number. In summary, it is concluded that the guideline values and limit values stipulated in applicable standards, recommendations and guidelines for vibrations, air shock waves and noise from blasting activities, as well as noise from drilling and boring will be met by ample margin. The impact on the surroundings from blasting activities during the construction of the final repository and the encapsulation facility is therefore expected to be very limited

  20. Vision og virkelighed

    DEFF Research Database (Denmark)

    Carlsen, Benny Bang

    Bogen behandler andetsprogsdidaktiske problemstillinger og emner som fx sproglig opmærksomhed, kontrastiv lingvistik, kommunikativ kompetence, andetsprogstilegnelsesteorier, intersprogsanalyse og kulturmødet....

  1. Skal vi synge den originale eller folkelige version af vores danske sange?

    DEFF Research Database (Denmark)

    Olsen, Jens Stig

    2015-01-01

    Artiklen behandler problemet med, at sange har en tendens til at ændre sig over tid og flittig brug, og via nogle kendte eksempler behandler den spørgsmålet om, hvordan vi kan forholde os til denne problematik.......Artiklen behandler problemet med, at sange har en tendens til at ændre sig over tid og flittig brug, og via nogle kendte eksempler behandler den spørgsmålet om, hvordan vi kan forholde os til denne problematik....

  2. Resource recovery from waste incineration residues

    DEFF Research Database (Denmark)

    Allegrini, Elisa

    Affaldsforbrænding er i mange lande en vigtig teknologi til behandling og energiudnyttelse af affald. Udover energi resulterer forbrænding også i produktion af asker. Størstedelen af askerne udgøres af slagge, som efter behandling har gode tekniske egenskaber og kan anvendes til bygge- og anlægsf...

  3. Hvad gør vi ved aborterede fostre?

    DEFF Research Database (Denmark)

    Mathar, Helle

    2011-01-01

    Artiklen behandler det etiske problem, at man på nogle hospitaler er begyndt at begrave aborterede fostre på kirkegårde.......Artiklen behandler det etiske problem, at man på nogle hospitaler er begyndt at begrave aborterede fostre på kirkegårde....

  4. Herodotos and Hemerodromoi

    DEFF Research Database (Denmark)

    Nielsen, Thomas Heine; Schwartz, Adam; Christensen, Dirk Lund

    2009-01-01

    Artiklen behandler de oldgræske 'hemerodromoi' - militære langdistanceilbud - i almindelighed og den athenske hemerodromos Pheidippides' løb fra Athen til Sparta i år 490 f.Kr., idet både historiske og fysiologiske forhold tages under behandling....

  5. Udformning af en forskningsprotokol

    DEFF Research Database (Denmark)

    Ridder, Hanne Mette Ochsner; Ottesen, Aase Marie

    2008-01-01

    Nogle demenssygdomme rammer især de forreste dele af hjernen, hvilket hos den enkelte person kan medføre svære psykiatriske symptomer. Der findes ingen specifik behandling af grundsygdommene for disse frontotemporaledemenstilstande, og symptomatisk medikamentel behandling af de psykiatriske sympt...

  6. New-onset atrial fibrillation after acute myocardial infarction in patients with left ventricular systolic dysfunction recorded by an Implantable Cardiac Monitor - Incidence, prediction and prognosis

    DEFF Research Database (Denmark)

    Jøns, Christian

    2010-01-01

    , med høj præcision, identificeres tidligt after AMI vha. metoder, der er følsomme for abnorm kardiel autonomon funktion. Fremtidige studier bør afklare om tidlig identificering af højrisiko-behandling samt præventiv behandling kan nedsætte den kardiovaskulære morbiditet og mortalitet i denne gruppe...

  7. Implementation of life cycle assessment models in solid waste management

    DEFF Research Database (Denmark)

    Damgaard, Anders

    Teknologier til behandling af affald bliver løbende forbedret, og antallet af forskellige måder at behandle affaldet på er stigende. Det er derfor nødvendigt at finde en metode til at vurdere, hvad der er den mest optimale kombination af teknologier til affaldsbehandling. En af de metoder, der er...

  8. De danske fanger i Sachsenhausen

    DEFF Research Database (Denmark)

    Danielsen, Astrid Marie Møller

    2009-01-01

    Specialet behandler systematisk tidligere danske kz- fangers interaktion med andre fangenationaliteter belyst ud fra erindringer og kendt forskning om KZlejren Sachsenhausen.......Specialet behandler systematisk tidligere danske kz- fangers interaktion med andre fangenationaliteter belyst ud fra erindringer og kendt forskning om KZlejren Sachsenhausen....

  9. Tovholder og forløbskoordinator

    DEFF Research Database (Denmark)

    Wulff, Christian; Vedsted, Peter

    2011-01-01

    KOL - sygdom, behandling og organisation giver en omfattende gennemgang af alle aspekter omkring KOL patienter fra tidlig opsporing og diagnose til forebyggelse, behandling og sundhedsvæsenets organisation. Vinklen er tværfaglig og alle kapitler er skrevet af specialister på deres felt. Bogen er ...

  10. Taxonomic and functional diversity of microbial communities in rapid sand filters for groundwater treatment

    DEFF Research Database (Denmark)

    Gülay, Arda

    Grundvand er i mange lande en væsentlig kilde til drikkevand. Grundvand af høj kvalitet kræver kun en simple behandling for at producere drikkevand til forbrugerne. Ofte er hurtig sandfiltrering, efter en forudgående beluftning, en tilstrækkelig behandling, uden behov for kloring. Et hurtig sandf...

  11. Blødningsforstyrrelser hos kvinder

    DEFF Research Database (Denmark)

    Astrup, Karen

    1994-01-01

    Efteruddannelsesartikel for praktiserende læger om undersøgelse og behandling af blødningsforstyrrelser hos kvinder i almen praksis. Udgivelsesdato: 1994......Efteruddannelsesartikel for praktiserende læger om undersøgelse og behandling af blødningsforstyrrelser hos kvinder i almen praksis. Udgivelsesdato: 1994...

  12. Kazuo Ishiguros romaner i helteperspektiv, specielt An Artist of the Floating World

    DEFF Research Database (Denmark)

    Klitgård, Ebbe

    2006-01-01

    På baggrund af en forfatterskabskarakteristik behandles Kazuo Ishiguros romaner i helteperspektiv og i forlængelse heraf foretages en romananalyse af An Artist of the Floating World fra 1986.......På baggrund af en forfatterskabskarakteristik behandles Kazuo Ishiguros romaner i helteperspektiv og i forlængelse heraf foretages en romananalyse af An Artist of the Floating World fra 1986....

  13. De nye myter

    DEFF Research Database (Denmark)

    Krogsdal, Iben Egekvist

    Selvudvikling og selvrealisering i en psykologiseret tidsalder. Bogen er en omskrivning af min ph.d.-afhandling og behandler psykologiseringen af det moderne samfund ud fra terapiformen NLP.......Selvudvikling og selvrealisering i en psykologiseret tidsalder. Bogen er en omskrivning af min ph.d.-afhandling og behandler psykologiseringen af det moderne samfund ud fra terapiformen NLP....

  14. Europa

    DEFF Research Database (Denmark)

    Hansen, Ole Erik

    2000-01-01

    Artiklen behandler, hvordan Europa blev centrum for den globale økonomiske udvikling, og hvilken rolle nationalstaterne har spillet for Europas udvikling. Derudover behandles det, hvordan den europæiske integrationsproces kan ses som et forsøg på at genskabe Europas centrale politiske og økonomiske...

  15. Trækonstruktioner

    DEFF Research Database (Denmark)

    Larsen, H.J.; Riberholt, H.

    Denne anvisning behandler materialer til trækonstruktioner og beregning af sædvanlige elementer og konstruktioner i henhold til Trænormen fra 2003 med tillæg. Forbindelser behandles i SBI-anvisning 194: Trækonstruktioner. Forbindelser. Anvisningen er tænkt anvendt af projekterende og som lærebog ...

  16. A.R.T. – Aggression Replacement Training

    DEFF Research Database (Denmark)

    Harbo, Lotte Junker; Domben, Eskil

    2015-01-01

    Artiklen indeholder en kort introduktion, eksemplificeret ved case, af det manualbaserede program til behandling af udadreagerende unge Aggression Replacement Training.......Artiklen indeholder en kort introduktion, eksemplificeret ved case, af det manualbaserede program til behandling af udadreagerende unge Aggression Replacement Training....

  17. Kreditret 2010/2011

    DEFF Research Database (Denmark)

    Werlauff, Erik

    Bogen giver et koncentreret indblik i og overblik over regler og praksis vedrørende kredit til virksomheder, herunder spørgsmål i relation til gældsbrevsloven, kreditaftaleloven, digital tinglysning mv. Også spørgsmål om tinglig sikkerhed i form af virksomhedspant og fordringspant behandles, till......, tillige med det international-privatretlige lovvalg i kredit- og panteretlige spørgsmål. Også ejendomsforbehold, leasing og factoring behandles. Endelig behandles spørgsmål om kaution og støtteerklæringer (comfort letters)....

  18. Forskningsbaseret viden kan bruges i praksis

    DEFF Research Database (Denmark)

    Braad, Mette; Bahnsen, Iben Bøgh; Axelsen, Hanne Clement

    2013-01-01

    Evidensbaseret praksis blev trænet i et samarbejde mellem sygeplejestuderende, kliniske vejledere og undervisere på sygeplejerskeuddannelsen i Aalborg. Resultatet af samarbejdet kommer nu præmature børn i CPAP-behandling til gode i form af systematisk soignering, aflastning og gel-behandling omkr......Evidensbaseret praksis blev trænet i et samarbejde mellem sygeplejestuderende, kliniske vejledere og undervisere på sygeplejerskeuddannelsen i Aalborg. Resultatet af samarbejdet kommer nu præmature børn i CPAP-behandling til gode i form af systematisk soignering, aflastning og gel...

  19. Hvordan diagnosticerer man astma hos børn?

    DEFF Research Database (Denmark)

    Hermann, Christian

    1997-01-01

    Astma og astmatisk bronkit har ens symptomatologi og behandling og kan med vore dages effektive og bivirkningssvage medicin selv i de lettere grader behandles. Symptomerne kender vi i praksis fra op mod 1/3 af småbørnene, kunsten består i at stille behandlingsindikationen. Der opridses overvejend...... at nødvendig rutine og erfaring heri kun kan opnås ved i dagligdagen at turde tage ansvaret for at stille diagnosen og behandle. Udgivelsesdato: 1997...

  20. Tandlægers erfaringer med at foreslå og få gennemført behandling med kroner og broer i privat praksis [Experiences of Danish dentists in private practice in motivating treatment with crowns and bridges

    DEFF Research Database (Denmark)

    Isidor, F.; Moore, R.

    2003-01-01

    English:What subjective experiences have Danish dentists in private practice to propose and implement treatment with crowns and bridges? A mailed questionnaire were completed and returned by 216 private practice dentists for a random sample from Aarhus. Of these, 22% thought...... and bridges, or lack of success in getting treatment completed hung mostly with practice type and location. Almost 76% of the dentists felt that it should be possible to learn how to motivate patients for the expensive treatments (eg bridges). More than 90% of the dentists felt the need for a better insurance...

  1. Does {sup 131}I-treatment of goitre result in an acute increase in the volume a function of the thyroid gland?; Medfoerer {sup 131}I-behandling af strufma en akut foroegelse af glandula thyreoideas volumen og funktion?

    Energy Technology Data Exchange (ETDEWEB)

    Nygaard, B.; Faber, J.O.; Hegedues, L.

    1995-12-01

    Many textbooks claim that radioiodine ({sup 131}I) treatment should be avoided in treatment of a goitre with substernal extension, due to fear of acute swelling of the gland with resulting respiratory problems. We examined patients with multinodular goitre, either nontoxic (n=20) or toxic (n=10) after treatment with {sup 131}I. An ultrasonically determined thyroid volume and thyroid function variables were investigated before and two, seven, 14, 21, 28 and 35 days after treatment. In nontoxic goitres the thyroid volume did not increase significantly, the maximum increase in the median volume being 4% on day 7. Serum levels of free T{sub 3} and free T{sub 4} indices increased by 20% (day 7) and 13% (day 14) (p=0.002), respectively. Likewise thyroid volume in toxic nodular goitre did not change significantly after {sup 131}I treatment. None of the patients presented symptoms of tracheal compression. We conclude that {sup 131}I treatment of nontoxic as well as toxic multinodular goitre does not seem to increase thyroid volume. (au) 18 refs.

  2. Treatment and disposal of radioactive wastes from nuclear power plants. Program for encapsulation, deep geologic deposition and research, development and demonstration; Kaernkraftavfallets behandling och slutfoervaring. Program foer inkapsling, geologisk djupfoervaring samt forskning, utveckling och demonstration

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-09-01

    Programs for RD and D concerning disposal of radioactive waste are presented. Main topics include: Design, testing and manufacture of canisters for the spent fuels; Design of equipment for deposition of waste canisters; Material and process for backfilling rock caverns; Evaluation of accuracy and validation of methods for safety analyses; Development of methods for defining scenarios for the safety analyses. 471 refs, 67 figs, 21 tabs.

  3. Giftige kokasser?

    DEFF Research Database (Denmark)

    Grønvold, Jonas Lindhardt; Stendal Svendsen, T; Holter, P;

    2005-01-01

    I moderne landbrug behandles kvæg mod rundorme og andre parasitter, med kemiske midler som udskilles i kokasserne. Dermed bliver kokasserne i nogle tilfælde giftige for det dyreliv som er knyttet til dem...

  4. Danske og finske PISA-resultater i et komparativt, kvalitativt perspektiv - men en spcialpædagogisk vinkel

    DEFF Research Database (Denmark)

    Andersen, Frans Ørsted

    2009-01-01

    Artiklen baserer sig på sammenlignende studier af hverdagen i almindelige danske og finske folkeskoler. Fokus er bredt på klasserumsledelse og undervisningsdifferentiering - men også detaljer som skolemadsordninger, undervisningsmaterialer og frikvartersordninger behandles. Desuden omtales finsk ...

  5. Moderne Økonomistyring og Kalkulation

    DEFF Research Database (Denmark)

    Nielsen, Steen

    1998-01-01

    Artiklen behandler sammenhængen mellem virksomhedens økonomistyring og virksomhedens produktionsforhold, specielt i relation til virksomhedens kalkulationsforhold. Sammentidig opstilles mulige sammenhænge til antal cost pools, cost drivers, kalkulationsfilosofi mv....

  6. Bange anelser om ny anbringelsesreform

    DEFF Research Database (Denmark)

    Kildedal, Karin

    2004-01-01

    Artiklen omhandler en analyse af den anbringelsereform, der er under behandling i folketinget i 2004. Analysen problematiserer, at staten fortsat prøver at kvalificere det sociale arbejdes praksis gennem lovgivning....

  7. Må journalister bryde loven for at oplyse befolkningen?

    DEFF Research Database (Denmark)

    Rytter, Jens Elo

    2010-01-01

    Artiklen behandler spørgsmålet om, hvorvidt journalister skal straffes, når de overtræder loven for at fremskaffe relevante oplysninger til offentligheden. Dansk retspraksis analyseres i lyset af EMRK art. 10.......Artiklen behandler spørgsmålet om, hvorvidt journalister skal straffes, når de overtræder loven for at fremskaffe relevante oplysninger til offentligheden. Dansk retspraksis analyseres i lyset af EMRK art. 10....

  8. Revisors kompetence - efteruddannelse

    DEFF Research Database (Denmark)

    Kiertzner, Lars

    2010-01-01

    Nærværende artikel behandler efteruddannelseskravene for revisorer. Først præsenteres kravene for godkendte revisorer i afsnit 1 om de kompetencekrav, der stilles for at opnå godkendelse, og i afsnit 2 om efteruddannelseskravene, som de med virkning fra 1.1. 2009 er udmøntet i revisorloven (RL), ...... revisor har en af specialistuddannelserne - CIA m.v. - er der derimod sådanne krav, der dog ikke behandles her. Udgivelsesdato: April 2010...

  9. Optisk Design og Optiske Systemer

    DEFF Research Database (Denmark)

    Dalsgaard, Erik

    1999-01-01

    På basis af geometriske bølgeaberrationer gives et grundlag for dimensionering af optiske systemer. En række numeriske metoder til analyse og optimering, baseret på 4. ordens bølgaberrationer samt endelig raytracing, behandles.......På basis af geometriske bølgeaberrationer gives et grundlag for dimensionering af optiske systemer. En række numeriske metoder til analyse og optimering, baseret på 4. ordens bølgaberrationer samt endelig raytracing, behandles....

  10. Platons ‘respekt’ for Protagoras

    DEFF Research Database (Denmark)

    Bloch, David

    2011-01-01

    Platons forhold til sofisten Protagoras behandles. Hvor forskningen oftest har hævdet, at Platon har stor respekt for denne, argumenteres der her for, at Platons dialog "Protagoras" viser alt andet end respekt.......Platons forhold til sofisten Protagoras behandles. Hvor forskningen oftest har hævdet, at Platon har stor respekt for denne, argumenteres der her for, at Platons dialog "Protagoras" viser alt andet end respekt....

  11. Tilsynsdiamanten i spændingsfeltet mellem soft law og hard law

    DEFF Research Database (Denmark)

    Rasmussen, Niels Skovmand

    2013-01-01

    Artiklen behandler de retskildemæssige spørgsmål, som Tilsynsdiamanten udstedt af Finanstilsynet giver anledning til. Dette sker på baggrund af forskellige teorier omkring soft law og hard law.......Artiklen behandler de retskildemæssige spørgsmål, som Tilsynsdiamanten udstedt af Finanstilsynet giver anledning til. Dette sker på baggrund af forskellige teorier omkring soft law og hard law....

  12. Internationale joint ventures - udvalgte selskabsretlige problemstillinger

    DEFF Research Database (Denmark)

    Sørensen, Karsten Engsig

    2001-01-01

    Artiklen behandler en række problemstillinger som er særlige for joint ventures stiftet i selskaber af aktie-, anpartsselskabstypen. Bl.a. behandles en række problemer omkring joint venture aftalens forhold til selskabets vedtægter samt en række problemstillinger knyttet til det forhold at der er...... etableret fælles kontrol over joint venture selskabet....

  13. Ross - for altid?

    DEFF Research Database (Denmark)

    Blume, Peter Erik

    2011-01-01

    Med baggrund i Jens Ewalds bog om Alf Ross omtaler artiklen en række de problemstillinger, som bogen behandler, samt vurderer den betydning, Ross har haft og måske fortsat har. Afslutningsvis betones den juridiske biografis betydning.......Med baggrund i Jens Ewalds bog om Alf Ross omtaler artiklen en række de problemstillinger, som bogen behandler, samt vurderer den betydning, Ross har haft og måske fortsat har. Afslutningsvis betones den juridiske biografis betydning....

  14. Oplevelsesøkonomi

    DEFF Research Database (Denmark)

    Madsen, Jan Halberg

    Bogen behandler dominerende teorier og værktøjer i alle led af værdikæden og belyser oplevelsesøkonomiens potentialer og mangfoldighed med eksempler og cases fra forskellige brancher. Teorierne behandles ud fra en praksisnær tilgang med cases og eksempler som fx Læsø Salt, Astrid Lindgren Verden,......, Hard Rock Cafe, Smukfest, Hverringe Gods og Eksperimentarium....

  15. hs-CRP、BNP 及血糖异常对老年急性心肌梗死患者预后的评估价值%The prognostic value of hs-CRP, BNP and dysglycemia in prognosing elderly patients with acute myocardial infarction

    Institute of Scientific and Technical Information of China (English)

    汪群芳

    2014-01-01

    Objective To develop knowledge of the value of hs-CRP, BNP and dysglycemia for prognosis of elderly patients with acute myocardial infarction .Method 180 elderly patients with acute myocardial infarction were selected as subjects for the study.The subjects were divided into two groups:a stress hyperglycemia group (random glucose level ≥7. 80mmol/L) and a non-stress hyperglycemia group (random glucose level 0.05);Compared with the non-stress hyperglycemia group, LVEF in the stress hyperglycemia group greatly decreased and LVEDD increased (P<0.05);Adverse cardiovascular events (within 30 days after onset) in the stress hyperglycemia group was much higher than that in the non-stress hyperglycemia group (P<0.05).Conclusion Blood sugar, hs-CRP and BNP can make a combination for accurate prognosis of the disease in question .%目的:探讨超敏C-反应蛋白(hs-CRP)、B型尿钠肽(BNP)及血糖异常对老年急性心肌梗死患者预后的评估价值。方法根据患者入院后首次血糖检测结果,随机将180例老年急性心肌梗死患者分为应激性高血糖组(随机血糖≥7.80mmol/L)及非应激性高血糖组(随机血糖<7.80mmol/L)。比较两组入院后血清hs-CRP、BNP、白蛋白、肌酸激酶同工酶(CK-MB)、超敏肌钙蛋白I(TNI)、心功能及发病1月内心血管不良事件发生率。结果应激性高血糖组血清hs-CRP、BNP水平显著高于非应激性高血糖组(P<0.05),但两组白蛋白、CK-MB、TNI水平差异不显著(P>0.05);应激性高血糖组左心室射血分数显著降低,左心室舒张末期内径测值显著升高,与非应激性高血糖组比较差异显著(均P<0.05),同时心血管不良事件发生率显著高于非应激性高血糖组(P<0.05)。结论血糖、血清hs-CRP及BNP三者联合检测可作为评估老年急性心肌梗死近期预后的指标。

  16. R vinder terræn forud for kommunalvalget

    DEFF Research Database (Denmark)

    Thomsen, Søren Risbjerg

    2009-01-01

    KOMMUNALVALG: S går tilbage og R frem i den nyeste prognose for kommunalvalget i november. Men SF står stadig som den store vinder.......KOMMUNALVALG: S går tilbage og R frem i den nyeste prognose for kommunalvalget i november. Men SF står stadig som den store vinder....

  17. Det sidste snit: VKO tæt på magten alene

    DEFF Research Database (Denmark)

    Thomsen, Søren Risbjerg

    2007-01-01

    PROGNOSE: VKO mangler kun to mandater for flertal i det sidste vejede snit, opdateret tirsdag kl. 10. Se også geografisk mandatprognose. Udgivelsesdato: 13. november......PROGNOSE: VKO mangler kun to mandater for flertal i det sidste vejede snit, opdateret tirsdag kl. 10. Se også geografisk mandatprognose. Udgivelsesdato: 13. november...

  18. Effect of intensive multifactorial treatment compared with routine care on aortic stiffness and central blood pressure among individuals with screen-detected type 2 diabetes

    DEFF Research Database (Denmark)

    Johansen, Nanna Borup; Charles, Morten; Vistisen, Dorte;

    2012-01-01

    herigennem effekten af intensiv multifaktoriel behandling sammenlignet med rutine behandling i almen praksis. Resultater: Patienterne in intensiv gruppen havde en 0,51 m/s (95%CI: -0,96; -0,05; p-værdi:0.03) sammenlignet med rutine behandlingsgruppen. Ekstrapolering af disse resultater på basis af en meta......-analyse om pulsbølgehastighed, svarer den difference på 0,51 m/s til en relativ risiko reduktion på 7% af intensiv multifaktoriel behandling sammenlignet med rutine. Men vi kan dog ikke konkludere at en reduktion i aorta stivhed og reducerer incidencen af kardiovaskulære tilfælde. For at bekræfte denne teori...

  19. Social kapital- introduktion til Robert Putnam

    DEFF Research Database (Denmark)

    Skaarup, Inge Marie

    2011-01-01

    Artiklen behandler de tre centrale begreber i Robert Putnams teori om social kapital. Det drejer sig om følgende: Fælles normer for generaliseret gensidighed, netværk og social tillid. Begreberne beskrives og diskuteres, bl.a. ved brug af eksempler fra pædagogisk praksis.......Artiklen behandler de tre centrale begreber i Robert Putnams teori om social kapital. Det drejer sig om følgende: Fælles normer for generaliseret gensidighed, netværk og social tillid. Begreberne beskrives og diskuteres, bl.a. ved brug af eksempler fra pædagogisk praksis....

  20. Nye endokrine behandlinger forlænger overlevelsen ved kastrationsresistent prostatacancer

    DEFF Research Database (Denmark)

    Brasso, Klaus; Thomsen, Frederik Birkebæk; Berg, Kasper Drimer;

    2013-01-01

    Endokrin behandling af prostatacancer (PCa) har været anvendt i mere end 60 år og har stadig en væsentlig plads i behandlingen af patienter med avanceret PCa. Hos en voksen mand opretholder androgener celleantallet i prostata og undertrykker apoptose. Ophæves den androgene stimulation opnås en...... dobbeltvirkning: hæmning af DNA syntese og proliferation samt aktivering af apoptose. Kastrationsbehandling i form af orkiektomi eller behandling med LHRH agonister/antagonister er standard hos patienter med avanceret PCa, men effekten er tidsbegrænset og såkaldt kastrationsresistent progression af PCa optræder...

  1. Smitte via håndtryk kan udløse erstatning

    DEFF Research Database (Denmark)

    Henschel, Rene Franz

    2008-01-01

    Artiklen behandler hospitalers erstatningsansvar efter dansk rets alminddelige regler samt efter lov om klage- og erstatningsadgang inden for sundhedsvæsenet såfremt patienter eller besøgende smittes via håndtryk på danske hospitaler mv. Udgivelsesdato: 26092008......Artiklen behandler hospitalers erstatningsansvar efter dansk rets alminddelige regler samt efter lov om klage- og erstatningsadgang inden for sundhedsvæsenet såfremt patienter eller besøgende smittes via håndtryk på danske hospitaler mv. Udgivelsesdato: 26092008...

  2. Moms og fast ejendom

    DEFF Research Database (Denmark)

    Edlund, Hans Henrik

    1999-01-01

    I artiklen gives et overblik over, hvorledes fast ejendom behandles momsmæssigt. Derfor findes en kort skitsering af reglerne for moms på byggearbejder, afgrænsningen mellem momspligtig og momsfri udlejning, muligheden for frivillig registrering af udlejning samt opgørelse af reguleringsforpligte......I artiklen gives et overblik over, hvorledes fast ejendom behandles momsmæssigt. Derfor findes en kort skitsering af reglerne for moms på byggearbejder, afgrænsningen mellem momspligtig og momsfri udlejning, muligheden for frivillig registrering af udlejning samt opgørelse af...

  3. Kommende standarder for revisors ydelser - "Efter clarity"

    DEFF Research Database (Denmark)

    Kiertzner, Lars

    2011-01-01

    Atiklen præsenterer på et overordnet niveau kommende standarder med videre fra IAASB. Formålet er at give et samlet overblik over, hvad der kan forventes i de kommende år. Den første og største del af artiklen behandler allerede igangsatte projekter, der befinder sig et sted i tilblivelsesprocess...... ISA 700 om revisionspåtegningen ISA 720 om andre oplysninger i regnskaber og ISRE 2400 om review. Andre projekter om vejledninger (IAPS), andre erklæringsopgaver og beslægtede opgaver behandles kun perifert....

  4. A retrospective data acquisition and evaluation on the characterization and prognosis for 776 patients with differentiated thyroid carcinomas in the Klinik und Poliklinik fuer Nuklearmedizin der Universitaet zu Koeln in the period from 1990 to 2005; Eine retrospektive Datenerhebung und Auswertung zur Charakterisierung und Prognose von 776 Patienten mit differenziertem Schilddruesenkarzinom der Klinik und Poliklinik fuer Nuklearmedizin der Universitaet zu Koeln im Zeitraum von 1990-2005

    Energy Technology Data Exchange (ETDEWEB)

    Meixner, Markus

    2011-06-22

    The author describes the retrospective data acquisition and evaluation on the characterization and prognosis for 776 patients (average age 40:1 years) with differentiated thyroid carcinomas in the Klinik und Poliklinik fuer Nuklearmedizin der Universitaet zu Koeln in the period from 1990 to 2005. The methodology includes patient-relevant data, examination data, imaging techniques and biochemical tests. Clinically important differences were found for papillary and follicular thyroid carcinoma. Further differences concern the localization of metastases. The author discusses the prognostic significance of the primary tumor radius in comparison with the so-called TNM classification for papillary and follicular thyroid carcinomas. It is concluded that the new version of the TNM classification offers only slight advantages with respect to the former version. It was also shown that the primary tumor size is adequate for prognostic estimations.

  5. Ambulanceudrykning i København, Odense og Ringkøbing Amt. Resultater fra Sundhedsministeriets og Amtsrådsforeningens stikprøveundersøgelse 1990. 2. Ambulancemandskabets behandling, lægestøtte og diagnosemønster

    DEFF Research Database (Denmark)

    Larsen, C F; Trier, H

    1992-01-01

    district with smaller towns (the County of Ringkøbing). The conditions of the patients were assessed by the ambulance staff: 7-12% of the patients transported had visible haemorrhage, 5-8% were unconscious, 4-7% were cyanotic, 2-3% had seizures and 1-2% had pareses. The serious cases tended to be most...

  6. Elevplaner i praksis

    DEFF Research Database (Denmark)

    Lund, Jens H

    2014-01-01

    Denne artikel behandler spørgsmålet om, hvordan eksterne styringstiltag i forhold til skolen gennemgår rekonstruktioner og omsætningsprocesser i det ’indre liv i skolen’. Artiklen er dermed et mikrosociologisk bidrag til den samlede forskning i styring og professioner. Jeg trækker i vid udstrækni...

  7. Kultur og etnicitet på arbejde

    DEFF Research Database (Denmark)

    Steensen, Jette Johanne Elisabeth; Day, Barbara Noel

    Gennem temaerne etnicitet, etnisk udvikling, kultur, multikulturalitet og racisme behandler bogen emnet interkulturel kompetence fra såvel et teoretisk som et praktisk perrspektiv. Teorierne giver dermed indblik i en lang række praksisfelter såsom socialt arbejde, skole hjem samarbejde, demokratisk...

  8. SOS

    DEFF Research Database (Denmark)

    Pecseli, Benedicta

    2015-01-01

    Dette støttepapir kan ikke stå alene. Teksten er alene tænkt som en hjælp til gruppearbejdet eller den enkelte midt i skriveprocessen og kan ikke anvendes, hvis man ikke er godt hjemme i grundbøgernes behandling af de samme emner. Det anbefales at følge undervisernes instrukser, anvisninger i gru...

  9. Erhvervsøkonomi i Slagelse i 25 år

    DEFF Research Database (Denmark)

    Scheuer, Steen; Andersen, Torben; Hansen, Kristian Rune

    2010-01-01

    Denne rapport behandler tre problemområder: 1. Om og i hvilket omfang det er lykkedes at fastholde dimittenderne fra Campus Slagelse beskæftigelsesmæssigt i regionen.2. Hvor mange der har taget en uddannelse oven på HA- eller HD-graden, fx en cand. merc., en cand. merc. aud., eller en masteruddan...

  10. Daoismus, Individuum und Masse in Döblins "Die drei Sprünge des Wang-Lun"

    DEFF Research Database (Denmark)

    Hansen, Flemming Finn

    2012-01-01

    Artiklen behandler Alfred Döblins forhold til den daoistiske filosofi og denne filosofis (herunder især det såkaldte "wu-wei"-princip om dobbeltheden af aktivitet og passivitet) betydning som grundlag for behandlingen af forholdet mellem individ og masse i hans kinesiske revolutionsroman "Die drei...

  11. Complementary or Contradictory Drug Policies

    DEFF Research Database (Denmark)

    Jourdan, Michael

    Almindeligvis antages det, at skadesreduktion udgør en fjerde søjle - som komplementerer kontrol, behandling og forebyggelse.  Denne placering er problematisk. De forskellige indsatser kan sættes i båse og man viser ikke inkompatibilitet mellem de forskellige indsatser nogen systematisk opmærksom...

  12. Bedre boligplaner

    DEFF Research Database (Denmark)

    Ranten, K.; Vedel-Petersen, F.

    Meddelelsen behandler brugskravene til boligens plan. Først opstilles detaljerede arealkrav ud fra beboernes aktiviteter, dernæst beskrives hvordan aktiviteterne kan tilgodeses og fordeles i planen, og endelig sammenfattes kravene i oversigter og checklister, der tjener som værktøj ved vurdering ...

  13. Concerning Styles

    DEFF Research Database (Denmark)

    Klitmøller, Jacob

    Dunn & Dunn Læringsstilsmodel er en indflydelsesrig og udbredt undervisningsmetode. Modellen er en del af et større felt af stilteorier i hvilket stile antages at være individuelle forskelle i hvordan personer behandler information og håndterer opgaver. Stile bliver oftest begrebsliggjort som for...

  14. Growth of the endocrine pancreas

    DEFF Research Database (Denmark)

    Gaarn, Louise Winkel

    Diabetes er karakteriseret ved en enten absolut eller relativ mangel paa insulin producerende ß-celler (henholdsvis type 1 og 2 diabetes). Den mest oplagte behandling ville vaere at genskabe den funktionelle ß-cellemasse ved enten regenerering eller celle terapi og dermed genindfoere normal gluco...

  15. Udlicitering og medarbejdere

    DEFF Research Database (Denmark)

    Schaumburg-Muller, Peer; Werlauff, Erik

    Bogen behandler offentlig udlicitering og privat outsourcing, særligt i forhold til lønmodtagerbeskyttelsen. Den sætter fokus på, hvornår en udlicitering eller outsourcing er ensbetydende med en virksomhedsoverdragelse i virksomhedsoverdragelseslovens forstand, og hvad konsekvenserne i så fald er...

  16. Hvem vandt 1.verdenskrig?

    DEFF Research Database (Denmark)

    Sodemann, Morten

    2008-01-01

    sygelighed og dødelighed i komplekse katastrofer inkluderer beskyttelse mod vold og overgreb, sikring af fødevarer,  vaccinations-kampagner, muligheder for håndvask, diarrékontrol, mor-barn sundhed og korrekt behandling af de hyppigste infektioner. Krige skaber flygtninge, og mobile befolkningsgrupper er...

  17. Hvem vandt 1. Verdenskrig? - Krige, katastrofer og epidemier har altid hjulpet hinanden

    DEFF Research Database (Denmark)

    Sodemann, Morten

    2008-01-01

    sygelighed og dødelighed i komplekse katastrofer inkluderer beskyttelse mod vold og overgreb, sikring af fødevarer, vaccinationskampagner, muligheder for håndvask, diarrékontrol, mor-barn sundhed og korrekt behandling af de hyppigste infektioner. Krige skaber flygtninge, og mobile befolkningsgrupper er...

  18. Kontraktetablering i supervision

    DEFF Research Database (Denmark)

    Mortensen, Karen Vibeke; Jacobsen, Claus Haugaard

    2007-01-01

    Kapitlet behandler kontraktetablering i supervision, et element, der ofte er blevet negligeret eller endog helt forbigået ved indledningen af supervisionsforløb. Sikre aftaler om emner som tid, sted, procedurer for fremlæggelse, fortrolighed, ansvarsfordeling og evaluering skaber imidlertid tryghed...

  19. Effectiveness of a training course for general practice nurses in motivation support in type 2 diabetes care

    DEFF Research Database (Denmark)

    Juul, Lise; Maindal, Helle T; Zoffmann, Vibeke

    2014-01-01

    praksis. Kurset omhandlede, hvordan man inden for de aktuelle rammer for type 2 diabetes behandling kan anvende ”Self-determination Theory, en motivationsteori om underliggende årsager for handlinger. Effektiviteten blev evalueret i et cluster-randomiseret pragmatisk design, der inkluderede 40 danske...

  20. Privat voldgift med offentligretlige delspørgsmål

    DEFF Research Database (Denmark)

    Werlauff, Erik

    2008-01-01

    Artiklen behandler de offentligretlige delspørgsmål, der kan opstå under en voldgiftssag, fx vedrørende el-, varme-, naturgas- og anden forsyningslovgivning, national eller fællesskabsretlig konkurrencelovgivning, forskrifter om statsforvaltningens godkendelse af vilkårene for udtræden af fællesk...

  1. Udvikling af virksomhedens transformationssystem (produktions- og distributionssystemet)

    DEFF Research Database (Denmark)

    Pagh, Janus Dore

    Denne ph.d.-afhandling behandler emnet udvikling af den industrielle produktionsvirksomheds transformationssystem, der omfatter virksomhedens samlede produktions- og distributionssystem. Der er i de senere år komet stigende fokus på virksomhedernes evne til at skabe differentieret og kundetilpass...

  2. Towards applied integrationism

    DEFF Research Database (Denmark)

    Nielsen, Charlotte Marie Bisgaard

    2011-01-01

    Forsøg med Aspergerklasser fortsættes i Danmark. Artiklen giver bud på hvorfor Aspegere og lærere i konventionelle sammenhænge oplever kommunikationsproblemer i et integrationelt perspektiv og skitserer rammerne for en dybere behandling af emnet med inddragelser af perspektiver som Asperger...

  3. Notat vedr. regn, rørdimensionering og bassindimensionering

    DEFF Research Database (Denmark)

    Bentzen, Thomas Ruby

    Dette notat vil redegøre for simple men meget anvendte metoder til dimensionering af afløbssystemer. Notatet vil primært behandle overfladevand(regnvand) som på en tilfredsstillende måde skal kunne ledes gennem afløbssystemet. Såfremt f.eks. husspildevand skal medtages er dimensioneringsprocedure...

  4. Depression og placebo

    DEFF Research Database (Denmark)

    Christensen, Kaj Sparle

    2016-01-01

    Metaanalyser har længe dokumenteret, at effekten af behandling med antidepressive lægemidler er begrænset sammenlignet med effekten af placebobehandling. Antidepressive lægemidler er kun sikkert virksomme hos svært deprimerede personer. Psykoterapi og antidepressive lægemidler er lige effektive h...

  5. Professionel kompetence og uddannelse

    DEFF Research Database (Denmark)

    Hedegaard, Karen Marie

    Specialet behandler forholdet mellem professionel kompetence og uddannelse gennem en undersøgelse og diskussion af teorier og forskning om professionsbegrebet i sociologien historisk og aktuelt, bl.a. Talcott Parsons, MaxWeber og Thomas Mathiesen, og diskuterer forskellige forståelser af...

  6. Passage 74

    DEFF Research Database (Denmark)

    , er spørgsmålet om, hvad litteraturvidenskaben stiller op med alle de værker, der falder uden for de 'finlitterære' genrer, litteraturhistorien traditionelt behandler. Andre spørgsmål lyder, hvad det vil sige, at en roman er en fiktionsgenre, og hvordan en veletableret genre som lyrik kan vedblive...

  7. Pårørendeinddragelse

    DEFF Research Database (Denmark)

    Hansen, Jeppe Oute

    2014-01-01

    "Introduktion: Det er et væsentligt sundhedspolitisk indsatsområde at inddrage pårørende i pleje, behandling og rehabilitering af mennesker med sindslidelser såvel som mennesker med somatiske lidelser. Med udgangspunkt i eksempler fra psykiatriske sammenhænge anlægges i dette kapitel et mere krit...

  8. Early literacy and inclusion

    DEFF Research Database (Denmark)

    Jensen, Anders Skriver

    Dette paper behandler skriftsprogstilegnelse med særligt henblik på inklusion. Det analyserer aktuel dansk policy, og giver et eksempel på inkluderende praksis vha. en såkaldt sproghistorie (EASE-projektet). Dette paper diskuterer også et amerikansk paper om inklusion og skriftsprogstilegnelse, o...

  9. Omkostningseffektivitet ved hypertensionsbehandling med Losartan i Danmark

    DEFF Research Database (Denmark)

    Keiding, Hans; Hildebrandt, Per; Burke, Thomas;

    2006-01-01

    Formålet med denne analyse var set såvel fra samfundets som fra det danske sundhedsvæsens perspektiv at evaluere omkostningseffektiviteten af losartan sammenlignet med atenolol ved behandling af hypertension, baseret på Losartan Intervention For Endpoint (LIFE)-undersøgelsens data Udgivelsesdato...

  10. Folkeretlige problemstillinger i forbindelse med konflikten mellem Ukraine og Rusland

    DEFF Research Database (Denmark)

    Buhl, Kenneth Øhlenschlæger

    Konflikten mellem Ukraine og Rusland udgør en trussel mod den internationale retsorden og dermed også hele den europæiske orden. Med henblik på at give et grundlag for at forstå omfanget af dette aspekt af konflikten behandles her lovligheden af nogle af de handlinger, som har været konfliktens...

  11. Efterisolering af etageboliger

    DEFF Research Database (Denmark)

    Munch-Andersen, Jørgen

    Denne anvisning behandler efterisolering af etageboliger bygget i perioden 1850-1977. Der gøres rede for de grundlæggende principper for efterisolering og de bygningsfysiske krav til de enkelte bygningsdele. Anvisningen indeholder desuden vejledning i, hvordan efterisolering udføres i henholdsvis...

  12. Motion Planning for Humanoid Robots Based on Virtual Constraints Extracted from Recorded Human Movements

    DEFF Research Database (Denmark)

    Mettin, Uwe; La Hera, P.; Freidovich, L.

    2008-01-01

    Inden for robotområdet er der stor interesse for at udvikle strategier og algoritmer som kan skabe menneskelige bevægelser. Denne artikel behandler bevægelsesplanlægning for humanuide robotter som er baseret på konceptet om virtuelle holonomiske begrænsninger. For det første analyseres et sæt kin...

  13. Udpegning af risikolokaliteter på det tosporede vejnet i åbent land baseret på data om vejens karakteristika

    DEFF Research Database (Denmark)

    Andersen, Camilla Sloth

    registreringsgraden er siden 2001 faldet fra, at 18,5 % af de tilskadekomne, der behandles på skadestue, også blev registreret i den officielle ulykkesstatstik, til at andelen, der blev registreret i 2011, er nede på 10 %. De danske vejmyndigheder, heraf særligt kommunerne, har derfor vanskeligt ved at udpege sorte...

  14. Von der pöbelhaften Eigenwärme zum Pulsschlag des Lebens - der literarische Vitalismus im deutschsprachigen Raum 1918-1933

    DEFF Research Database (Denmark)

    Nielsen, Louise Ebbesen

    2010-01-01

    I "Fra pøbelens lunkne selvgodhed til livets pulsslag – den litterære vitalisme i det tysksprogede rum 1918-1933" behandler jeg vitalismen i udvalgte værker i den tyske litteratur (Bertolt Brecht, Ernst Jünger, Gottfried Benn, Gerhart Hauptmann og Carl Zuckmayer). Vitalismen er særdeles udbredt i...

  15. Letbeton 1

    DEFF Research Database (Denmark)

    Meyer, E.V.; Nerenst, P.

    Denne SBI-anvisning giver en orienterende gennemgang af alle de forhold ved letbeton, som det er gavnligt for de fleste af byggeriets folk at have viden om. Den behandler fortrinsvis letbetoner fremstillet ved skumdannelse og ved luftudviklilng. Selve fremstillingsprocessen er kort beskrevet, sål...

  16. Personlighedsudredninger i børne- og undgomspsykiatrisk regi

    DEFF Research Database (Denmark)

    Møller, Lone Hjerrild; Lichtenstein, Mia Beck

    2012-01-01

    personlighedstestene NEO PI-R og Rorschach. Målgruppen var unge i alderen 15-18 år i behandling i ungdomspsykiatrien. Konklusionen var, at NEO PI-R kan anvendes i en ungdomspsykiatrisk population, men at der skal tages forbehold for bl.a. alder. Sammen med Rorschach giver de to tests en stærk beskrivelse af en klients...

  17. Acute dental pain II

    DEFF Research Database (Denmark)

    Jonasson, Peter; Kirkevang, Lise-Lotte; Rosen, Annika;

    2016-01-01

    undersøgelse er afgørende for både diagnosticering og behandlingsvalg. Der vil i denne artikel blive fokuseret på diagnostik og behandling af pulpitis, pulpal nekrose og apikal parodontitis, parodontal abscess og endodontisk-parodontale læsioner, pericoronitis og post-operative problemer. Når en patient...

  18. A stakeholder approach to green innovation management

    DEFF Research Database (Denmark)

    Ulhøi, John Parm

    Artiklen handler om interessentledelse: hvordan virksomhedsledere hele tiden må arbejde med de mange krav og forventninger, der stilles til dem fra forskellige interne og eksterne interessenter. Der præsenteres en analytisk metode (SPOT-analysen), som behandler, hvordan ledelsen med fordel kan in...

  19. Antithrombotic drugs and interactions in ischemic heart disease

    DEFF Research Database (Denmark)

    Charlot, Mette Gitz

    2011-01-01

    antithrombotisk behandling. Afhandlingen er udformet på baggrund af tre store observationelle farmako-epidemiologiske studier baseret på danske landsdækkende registre med oplysninger om indlæggelser, diagnoser, indløst receptpligtig medicin, dødsfald, dødsårsager, og socioøkonomiske data. Oplysningerne fra de...

  20. Nitrification biokinetics in rapid sand filters for drinking water treatment

    DEFF Research Database (Denmark)

    Tatari, Karolina

    Danmarks drikkevandsforsyning er udelukkende baseret på grundvand – og mere end 2500 vandværker behandler hver dag vand til de danske forbrugere. Selv om denne vandbehandling betegnes som simpel, er den i virkeligheden baseret på komplicerede mikrobielle processer, som vi hidtil har vidst relativ...

  1. Klasseledelse, inklusion og differentiering

    DEFF Research Database (Denmark)

    Jørgensen, Christina; Mottelson, Martha

    2014-01-01

    Kapitlet behandler forholdet mellem de tre begreber klasseledelse, inklusion og differentiering og ser på, hvordan de folder sig ud i folkeskolens praksis. Der tages afsæt i en definition af klasseledelse som alle de redskaber, læreren tager i anvendelse med henblik på at få timen til tage form på...

  2. ”Hospitalet bliver aldrig et godt sted”

    DEFF Research Database (Denmark)

    Haa, Berit Pedersen; Aagaard, Hanne

    2014-01-01

    Ved ankomsten i Skadestuen er børn ofte chokerede, utrygge, angste og har smerter. De træder ind et ukendt sted, hvor der er fremmede lyde og lugte - og hvor de skal undersøges og behandles. Formålet med udviklingsprojektet ”Hospitalsklovne i Skadestuen” er at undersøge, hvorvidt hospitalsklovne ...

  3. Håndtering af illikviditet i APV modellen

    DEFF Research Database (Denmark)

    Brandt, Mads; Dalgaard, Rune; Plenborg, Thomas

    2014-01-01

    Denne artikel behandler illikviditetspræmien i forbindelse med værdiansættelser. Mere præcist udledes den korrektion af illikviditetspræmien, der skal foretages, for at sikre konsistens i værdiansættelsen med henholdsvis Discounted Cash Flow (DCF) og Adjusted Present Value (APV) modellen. Artiklen...

  4. Kommunikationskritisk kompetence

    DEFF Research Database (Denmark)

    Bundsgaard, Jeppe; Frahm, Henrik; Christiansen, Eva Therese;

    Bogen Kommunikationskritisk kompetence undersøger, hvordan danskfaget med sine begreber, tilgange og metoder kan understøtte, at eleverne udvikler kompetencer, så de kan håndtere udfordringer i de situationer, de står i. Kommunikationskritisk kompetence behandler emner som politisk kommunikation,......, reality-tv, computerspil, køn, dokumentarfilm og børnelitteratur....

  5. International økonomi. 3.udgave

    DEFF Research Database (Denmark)

    Madsen, Erik Strøjer; Nielsen, Jørgen Ulff-Møller; Pedersen, Kurt

    Tredie udgave af International Økonomi er udvidet en del i forhold til den forrige. De vigtigste udvidelser er den 'nye udenrigshandelsteori', som er udskilt i et selvstændigt kapitel, og koordination af den økonomiske politik mellem landene, der i bogens afsluttende kapitel behandles teoretisk s...

  6. Hvis Al Bashir kommer forbi

    DEFF Research Database (Denmark)

    Kjeldgaard-Pedersen, Astrid

    2009-01-01

    For første gang i sin historie udstedte Den Internationale Straffedomstol (»ICC«) i marts 2009 en arrestordre mod et siddende statsoverhoved. Artiklen behandler en række spørgsmål om statsrepræsentanters immunitet, fortolkningen af Statutten for Den Internationale Straffedomstol (»ICC Statutten«)...

  7. Børsretten I

    DEFF Research Database (Denmark)

    Clausen, Nis Jul

    Bogen behandler følgende emner: Den EU-retlige og den danske børsretlige regulering Værdipapirhandelslovens centrale begreber og krav Reguleringen af værdipapirmarkedets virksomheder Krav til værdipapirhandlere, herunder kunderelationer Det børsnoterede selskab og reguleringen heraf Tilsyn og san...

  8. A study of young Parisian speech

    DEFF Research Database (Denmark)

    Hansen, Anita Berit

    2012-01-01

    Fransk talt i Paris har gennem århundrede udgjort en model for den øvrige franske befolkning. Udtalen er dog på ingen måde fri for variation eller forandring. Artiklen behandler udtalen hos 9 unge parisere (såvel studerende som personer med kort teknisk uddannelse), der tydeligvis deltager i fler...

  9. SundtHjem projektet

    DEFF Research Database (Denmark)

    Aarhus, Rikke; Ballegaard, Stinne Aaløkke; Hansen, Thomas Riisgaard

    for sundhedssystemet, hvor stadig mere behandling sker på centraliserede og specialiserede hospitaler, og hvor patienten i langt højere grad forventes at varetage væsentlig egenomsorg. For at udforske dette problemfelt har projektets partnere (Logica, Polycom, Aarhus Sygehus Skejby, Aarhus Universitet) arbejdet med en...

  10. Kost - mad - næring

    DEFF Research Database (Denmark)

    2010-01-01

    Kapitlet handler om kost og forskellige aspekter af menneskeføde og dens indtagelse. Mad- og måltidspolitik i institutionerne behandles, og ligeså næringsstofferne og deres betydning for kroppens sundhed, herunder også konsekvenserne af fejlernæring. Også allergi og intolerans over for fødeemner ...

  11. Kliniske ganganalyser - hvad er det?

    DEFF Research Database (Denmark)

    Bencke, Jesper

    2007-01-01

    Artiklen beskriver kliniske biomekaniske ganganalyser som et redskab til objektiv 3-dimensionel beskrivelse af gang. I artiklen gennemgås procedurer for undersøgelsen, behandling af data, samt afrapportering og tværfaglig konference med deltagelse af involverede læger, biomekanikere og fysioterap...

  12. Sygepleje mellem pakker og personer

    DEFF Research Database (Denmark)

    Larsen, Niels Sandholm

    og af problemer med at rekruttere og fastholde sundhedsfaglig arbejdskraft. Som følge af demografiske ændringer antages særligt behandling og rehabilitering af kronisk syge ældre at udgøre et voksende indsatsområde. Sygeplejerskernes faglige organisation har været aktiv i etablering af kommunale...

  13. Poser af papir og plast

    DEFF Research Database (Denmark)

    Thygesen, Jette

    2007-01-01

    Artiklen behandler de problemstillinger der er i forbindelse med fortolkning af det afgiftspligtige vareområde. I henhold til lov om afgift af visse emballager, poser, engangsservice, og pvc-folier, svares der afgift af poser, såfremt de frembyder bestemte karakteristika, herunder særligt om de er...

  14. American Literature after September 11

    DEFF Research Database (Denmark)

    Bjerre, Thomas Ærvold

    2009-01-01

    Artiklen gennemgår de amerikanske romaner, der behandler terrorangrebene 11. september og tiden derefter. Opsummerer fælles træk ved romanerne og fokuserer til sidst på Don DeLillos Falling Man. Udgivelsesdato: Februar 2009...

  15. Kan forskellige velfærdsregimer betjenes af harmoniserede uddannelser?

    DEFF Research Database (Denmark)

    Jensen, Niels Rosendal

    2009-01-01

    Artiklen behandler dels Bologna-processen, dels etableringen af et marked for serviceydelser. Begge dele berører hidtidige sammenhæng mellem national uddannelse til et nationalt arbejdsmarked. Dog understreges, at den fortsatte nationale akkreditering af uddannelser modificerer virkningerne af...

  16. Andersen and Tradition. Animal Tales and 'Zaubermärchen'

    DEFF Research Database (Denmark)

    Pedersen, Viggo Hjørnager

    2010-01-01

    Artiklen behandler to delvis overlappende litterære former og Andersens forhold til dem. Det drejer sig om dyrefortællingen med personificerede dyr og eventyret med overnaturlige væsener, 'trylleeventyret'. Andersen arvede begge disse former og kom så på sin side til at danne forbillede for andre...

  17. La position de l'adjectif épithète : effets de focalisation à l'intérieur du syntagme nominal

    DEFF Research Database (Denmark)

    Nølke, Henning

    1996-01-01

    Artiklen behandler problemet om, hvorvidt det attributive adjektiv skal stå foran eller efter substantivet på fransk. Det vises først, at ingen eksisterende teori tilbyder et enkelt forklarende princip. Forfatteren applicerer derpå sin fokaliseringsteori, som er i stand til at kombinere forskelli...

  18. Hovedlinjer i Erhvervsstrafferetten

    DEFF Research Database (Denmark)

    Langsted, Lars Bo; Greve, Vagn

    Bogen omhandler de generelle betingelser for strafansvar og beskrivelse af en række af de forbrydelser, der typisk begås i forbindelse med erhvervsudøvelse. Hertil kommer en gennemgang af retssystemets behandling af straffesager om erhvervskriminalitet....

  19. How nice to be good at it

    DEFF Research Database (Denmark)

    Gregersen, Frans

    2010-01-01

    De emner og forfattere der behandles er: tekst og undertekst i dagligsprog og fiktionsprosa: Ian McEwan, fortællerstilarter: Walter Scott og citatpraksis: dagligsproget. Artiklens pointe er at påvise sammenhængen mellem dagligsproget og kunstprosaens videre forarbejdning af effekter herfra....

  20. Medarbejdernes retsstilling ved grænseoverskridende overtagelse og fusion

    DEFF Research Database (Denmark)

    Hansen, Lone L.

    Bogen, der er en publiceret ph.d.-afhandling, analyserer en række komplekse spørgsmål om medarbejdernes retsstilling, når den virksomhed, de arbejder i, overtages af en udenlandsk virksomhed gennem majoritetsovertagelse, virksomhedsoverdragelse, fusion eller spaltning. Afhandlingen behandler over...

  1. Rehabilitation in Parkinson’s Disease

    DEFF Research Database (Denmark)

    Rose, Martin Høyer

    Parkinsons sygdom (PD) er en progredierende neurodegenerativ sygdom med gradvis udvikling af motoriske og non-motoriske symptomer. Dopaminerg behandling udgør en effektiv symptomatisk behandlingsform, men indebærer risiko for langtidsbivirkninger i form af svært behandlelige fluktuationer i...

  2. Prostate cancer and cardiovascular diseases: Risk and prognosis

    DEFF Research Database (Denmark)

    Jespersen, Christina Gade

    2014-01-01

    Formålene med dette ph.d. studie var at undersøge datakvaliteten af koderne for medicinsk og kirurgisk kastration i Landspatientregistreret, at estimere risikoen for akut myokardieinfrakt (AMI) og apopleksi efter behandling med medicinsk eller kirurgisk kastration, samt at bestemme betydningen af...

  3. Evidens for akupunktur til patienter med kvalme og opkastning i forbindelse med kemoterapi? Et litteraturstudie

    DEFF Research Database (Denmark)

    Pedersen, Birgith; Bundgaard Sørensen, Lene; Stricker, Lisbeth;

    2008-01-01

    Patienter, der får kemoterapi med højemetogene stoffer lider stadig af kvalme og opkastning trods understøttende behandling med moderne antieemtika som 5HT3-antagonister eksempelvis ondansetron. Akupunkturstimulation anvendes for flere lidelser i sundhedsvæsenet og det undersøges om der er evidens...

  4. Om retsinstituttet passiv identifikation i formueretten

    DEFF Research Database (Denmark)

    Holle, Marie-Louise

    2015-01-01

    ikke undergivet en behandling i sin helhed i dansk retslitteratur. Studiet af passiv identifikation lider navnlig under, at forholdet til andre retsfigurer er uafklaret. Det antages i både dansk og udenlandsk retsteori, at passiv identifikations anvendelsesområde er sammenfaldende med aktiv...

  5. Åbne læringsressourcer - mod en sociokulturel teori om læringsressourcer

    DEFF Research Database (Denmark)

    Dalsgaard, Christian

    2007-01-01

    Afhandlingen behandler spørgsmålet om, hvordan it-baserede læringsressourcer udvikles med udgangspunkt i et læringsteoretisk grundlag. Læringsressourcer forstås som alle typer af ressourcer eller materialer, der anvendes til at understøtte læreprocesser. Formålet med afhandlingen at opstille et t...

  6. Resultatstyring omkring børsintroduktioner

    DEFF Research Database (Denmark)

    Sommer, Rasmus S.

    2000-01-01

    I En artikel i FINANS/INVEST 7/00 behandler Jan Bo Jakobsen aktiemarkedets reaktioner på danske børsintroduktioner på kort og lang sigt. Jan Bo Jakobsen refererer resultater, der viser at IPO-aktierne på lang sigt i gennemsnit underperfor- mer overfor markedet, men finder ingen forlkaring herpå. ...

  7. Survival of patients with small cell lung cancer undergoing lung resection in England, 1998-2009

    DEFF Research Database (Denmark)

    Lüchtenborg, Margreet; Riaz, Sharma P; Lim, Eric

    2014-01-01

    Småcellet lungekræft behandles oftest med kemoterapi eller strålebehandling, bortset fra sygdomstilfælde på stadie et, hvor de kliniske retningslinjer anbefaler kirurgiske indgreb. Man kender dog ikke effekten af at tilbyde flere kirurgisk fjernelse af lungekræft. Ved at udnytte variationen i de ...

  8. I en højere sags tjeneste

    DEFF Research Database (Denmark)

    Langsted, Lars Bo; Jakobsen, Søren Sandfeld

    2014-01-01

    Artiklen behandler ud fra en retsdogmatisk metode nogle af de grundlæggende problemstillinger, regler, principper og hensynsafvejninger, der gælder, når staten eller private virksomheder vil gennemføre overvågning af borgerne og dermed gøre indgreb i retten til privatlivets fred. Særlig fokus er ...

  9. Hemmelig ransagning og brevstandsning i den digitale virkelighed

    DEFF Research Database (Denmark)

    Lentz, Lene Wacher

    2016-01-01

    Artiklen tager udgangspunkt i sager om databedrageri, hvor betalingskort misbruges til køb på internettet. Politiets adgang til private chatfora på nettet analyseres i forhold til de straffeprocessuelle tvangsindgreb hemmelig ransagning, aflytning og dataaflæsning. Desuden behandler artiklen den ...

  10. Coaching patients to self-care: a primary responsibility of nursing

    DEFF Research Database (Denmark)

    Hørdam, Britta

    2010-01-01

    Anmelselse af international forskning:Formål: En australsk undersøgelse har fokus på aktivt at støtte og guide ældre til en rehabiliterende egenomsorg efter udskrivelse fra behandling på sygehus. Metode: Med afsæt i grounded theory udvikles en model for rehabiliterende sygepleje, hvor sygeplejers...

  11. History of Education in Europe

    DEFF Research Database (Denmark)

    Haue, Harry

    2009-01-01

    Denne oversigtsartikel behandler børnearbejde i relation til skolegang og uddannelse. Fokus er på sammenhængene mellem samfundsudvikling og ændringer i børnens muligheder for formaliseret læring fra landbrugssamfundet via industrisamfundet til informationssamfundet, og den værdi børnearbejdet til...

  12. Paclitaxels farmakogenomik hos patienter med kræft i æggestokken

    DEFF Research Database (Denmark)

    Bergmann, Troels Korshøj; Mirza, Mansoor Raza; Andersen, Charlotte Brasch;

    Formål og baggrund: Paclitaxel (Taxol®) er et kemoterapeutikum der bruges til behandling af bl.a æggestokkræft. Paclitaxel doseres individuelt (175mg/m2) men alligevel er der klinisk betydende variation i forekomsten af bivirkninger (neurotoksicitet, kvalme/opkast, knoglemarvspåvirkning m...

  13. Live Speed Analysis, en app til hastighedsmålinger

    DEFF Research Database (Denmark)

    Bolet, Lars; Christensen, Peter Muhlig; Halskov-Sørensen, Asbjørn;

    2013-01-01

    I et bachelorprojekt har tre studerende udviklet en app, som kan registrere og behandle hastigheder ved den såkaldte spejlmetode. App'en er siden videreudviklet, så registreringerne stedfæstes, tidstemples og uploades til en fæIIes database. App'en er frit tilgængelig. Den kan bruges af...

  14. Mod en ny informationsret

    DEFF Research Database (Denmark)

    Andersen, Mads Bryde

    2009-01-01

    Artiklen fremlægger og diskuterer nogle af de tanker, der finder udtryk i afhandlingen »De informationsretlige grundsætninger«, som professor Henrik Udsen netop har forsvaret for den juridiske doktorgrad. I senere artikler i samme tidsskrift (s. 383 ff., s. 389 ff., s. 392 ff., s. 397 ff. og s. 400...... ff.)behandles andre elementer af afhandlingen....

  15. Den der ser, er den, der ses

    DEFF Research Database (Denmark)

    Bjerrum, Troels

    2010-01-01

    -Ponty og Alexander Lowen belyser, hvordan sind og krop er forbundet og Antonio Damasio's teori om menneskets bevidsthed demonstrerer, at indsigt i følelser, tanker og bevægelser er nøgle til, at det enkelte menneske opnår at handle aktivt frem for reaktivt. Afhandlingen behandler begrebet bevidsthed som...

  16. Translation as Transformation

    DEFF Research Database (Denmark)

    Klitgård, Ebbe

    2008-01-01

    Artiklen behandler de to tidligste oversættelser af Chaucer i Danmark, professor T.C. Bruuns oversættelse af Popes version af Chaucers The Wife of Bath's Prologue fra 1823, og skolebestyrer Louise Westergaards hæfte med oversættelse og referater af Chaucer fra 1853. Jeg viser hvordan en klassisk ...

  17. Efter selskabsreformen

    DEFF Research Database (Denmark)

    Werlauff, Erik

    2009-01-01

    Artiklen behandler de skatteretlige konsekvenser af den del af den store danske selskabsreform 2009/10, som fremtidigt tillader aktionær-, anpartshaver- og ledelseslån, når nogle grundlæggende betingelser er opfyldt. Nogle skatteretlige konsekvensændringer (en ny bestemmelse i ligningslovens § 16...

  18. Ud af Napoli

    DEFF Research Database (Denmark)

    Lausten, Pia Schwarz

    2016-01-01

    Artiklen præsenterer Elena Ferrantes romankvartet "Min geniale veninde" (2011-14). Indledningen behandler problemstillingen vedrørende forfatterens fortsatte ønske om at være anonym, hvorefter artiklen analyserer værket ud fra genremæssige, sproglige og tematiske kriterier. Artiklen er bygget op om...

  19. Behandlingseffekt af Digital Dermatitis

    DEFF Research Database (Denmark)

    Krogh, Kenneth; Thomsen, Peter

    2008-01-01

    af klovlidelser herunder især Digital Dermatitis. Klovregistreringerne viser, at der er stor dynamik og mange nyinfektioner af Digital Dermatitis svarende til problematikken ved mastitis. Behandlingseffekten ved Digital Dermatitis er høj (omkring 90 %) ved den udførte behandling. Behandlingen bestod...

  20. Review af Business Process Reengineering litteraturen fra 1990-98

    DEFF Research Database (Denmark)

    Wit, Camilla Kølsen de

    1998-01-01

    Formålet med papiret er dels at biddrage med et overblik over centrale kilder om BPR, og dels at kommentere udviklingen i litteraturens behandling af hhv. BPR begrebet og BPR projektet. Reviewet er bygget op om en kronologisk tabel, der opsummerer kildernes hovedsynspunkter....

  1. CAS i folkeskolens matematikundervisning med øget læringsudbytte for drenge på mellemtrinnet

    DEFF Research Database (Denmark)

    Mogensen, Arne; Bull, Adrian Rau; Hansen, Mette Hesselholt Henne

    2016-01-01

    Artiklen rapporterer et studie der skal afdække om brug af CAS-værktøjer (Computer Algebra Systems) i en matematikundervisning hvor rammen er undersøgende, eksperimenterende og procesorienteret, ændrer elevers tilgang til behandling af matematiske problemstillinger på en sådan måde at det øger...

  2. Forældreinddragelse i Vida

    DEFF Research Database (Denmark)

    Berliner, Peter; Kousholt, Dorte

    2012-01-01

    I VIDA-projektet indgår forældreinddragelse og -samarbejde som en betydningsfuld del. I undersøgelsen af VIDA-projektet er der foretaget interview med ledere i de deltagende institutioner. I dette kapitel behandles de dele af interviewene, der omhandler, hvordan lederne forstår betydningen af...

  3. Opsigtsvækkende nyt om derivater fra USA

    DEFF Research Database (Denmark)

    Thinggaard, Frank

    1997-01-01

    Der er opsigsvækkende nyt fra USA om den regnskabsmæssige behandling af derivater som terminskontrakter, futures, optioner, swaps m.v. Glem alt om historiske anskaffelsespriser. For derivater er der kun ét mål, som kan bruges: markedsværdier (fair-values). Glem alt om snakken om 'off-balance-sheet...

  4. Hans Tausen. Forskning. Historie. Teologi

    DEFF Research Database (Denmark)

    Dreyer, Rasmus Hoeg Colbjørn

    2010-01-01

    for disse betragtninger er, at Tausen ikke eksplicit kan forstås som 'luthersk'. En sådan teologisk rubricering er en receptionshistorisk applikation. Dette er fremstillingens fokus i første del. Denne del behandler den samlede, historiske reception af Tausen. Med udgangspunkt i de ældste betragtninger (fra...

  5. Akupunktur til patienten med kvalme og opkastning i forbindelse med kemoterapi - er der evidens for dette?

    DEFF Research Database (Denmark)

    Pedersen, Birgith; Sørensen, Lene Bundgaard; Stricker, Lisbeth

    2008-01-01

      Patienter, der får kemoterapi med højemetogene stoffer lider stadig af kvalme og opkastning trods understøttende behandling med moderne antieemtika som 5HT3-antagonister eksempelvis ondansetron. Akupunkturstimulation anvendes for flere lidelser i sundhedsvæsenet og det undersøges om der er evid...

  6. Kunstens psykologi og sansningens primat

    DEFF Research Database (Denmark)

    Levin, Kasper

    2012-01-01

    . Spørgsmålet er imidlertid om ikke kunstpsykologien udelukker sig selv fra væsentlige indsigter ved på denne måde at behandle kunstværker som traditionelt empiriske eller repræsentationelle genstande. Med udgangspunkt i en analyse af Sigmund Freuds tilgang til kunst vil jeg pege på filosoffen Gilles Deleuze...

  7. 'Forestillet læringsvej' i IT-baserede pædagogiske udviklingsprojekter

    DEFF Research Database (Denmark)

    Misfeldt, Morten

    2010-01-01

    I denne artikel indføres begrebet 'forestillet læringsvej', og det bruges til at beskrive forskellige tilgange til forholdet imellem udviklingsprojekters mål om at ændre praksis og de resultater, der kan komme ud af at undersøge denne praksisændring. Artiklen behandler det forhold, at interventio...

  8. Danskernes racisme

    DEFF Research Database (Denmark)

    Necef, Mehmet Ümit

    2010-01-01

    Jens Peter Frølund Thomsen, politolog fra Århus Universitet, har i bogen Konflikten om de nye danskere (2006) undersøgt danskernes holdninger til her-boende etniske minoriteter, herunder racismens omfang og dens former. Ar-tiklen diskuterer Thomsens definition på racisme og hans behandling af sin...

  9. Die Anomalie des Normalen

    DEFF Research Database (Denmark)

    Jahnke, Carsten

    2012-01-01

    Artiklen behandler spørgsmålet af de dokumenter, Christian I havde udstillet ved magtoverdragelsen i hertugdømmerne 1460. Imod den gamle opfatning, blev der gjort en difference mellem Christians håndfæstning i Ribe og en senere givet privilegium. Desuden blev betydningen af den 9 kapitel af håndf...

  10. Case report - curved femoral osteotomy for management of medial patellar luxation

    DEFF Research Database (Denmark)

    Allpass, Maja; Miles, James Edward

    2015-01-01

    Medial patellaluxation kan forårsages af femoral varus hos hund. Førhen har patienter med excessiv femoralvarus været korrigeret ved en lateralt placeret femoral kile-ostektomi. Her præsenteres en case, hvor en buet osteotomi blev anvendt til behandling af medial patellaluxation....

  11. Screening for diabetes: what do the results of the ADDITION trial mean for clinical practice?

    DEFF Research Database (Denmark)

    Lauritzen, Torsten; Borch-Johnsen, Knut; Davies, Melanie J

    2013-01-01

    Artiklen opsummerer de nuværende resultater fra ADDITION studiet. Forfatterne konkluderer at ADDITION studiet har skabt yderligere evidens til støtte for tidlig opsporing og behandling af patienter med uerkendt diabetes. Frem for at fokusere på populationsbaseret screening opfordre forfatterne pr...

  12. Cardiovascular risk reduction following diagnosis of diabetes by screening:

    DEFF Research Database (Denmark)

    Charles, Morten; Simmons, Rebecca; Williams, Kate

    2012-01-01

    Baggrund: Der er usikkerheder om behandlingen af diabetes tidligt i sygdommens forløb. Derfor er nogle praktiserende læger tilbageholdende for intensivt at behandle patienter med tidlig diabetes. I dette studie fra ADDITION Cambridge ville vi beskrive ændringen i modulleret kardiovaskullær risiko...

  13. Tuberkulose forårsaget af Mycobacterium africanum

    DEFF Research Database (Denmark)

    Bek, Dorte; Kjeldsen, Marianne Kirstine; Hansen, Nikolaj Friis;

    2010-01-01

    Tuberkulose (TB) forårsages af patogene arter fra Mycobacterium tuberculosis komplekset (MTBC) og har en incidens på cirka 7/100.000 i Danmark. På mistanke om TB hos en akut indlagt 40 årig afrikansk mand initieredes anti-TB behandling. Efter 13 timers indlæggelse afgik patienten ved døden. Fra l...

  14. Tætte parcelhusområder

    DEFF Research Database (Denmark)

    Jantzen, E.B.; Kaaris, H.; Pedersen, H.T.;

    Publikationen giver vejledning i planlægning af bebyggelser med individuelle parcelhuse på små grunde. Den præsenterer seks principmodeller for udstykninger og gennemgår det praktiske planlægningsgrundlag, der er basis for principmodellerne. Desuden behandles de byplanmæssige forhold, der har bet...

  15. Dømmer jeg - eller er jeg vågen?

    DEFF Research Database (Denmark)

    Hedegaard, Karen Marie

    2014-01-01

    Artiklen behandler begrebet dømmekraft ud fra et filosofisk og sociologisk perspektiv på ansvar og etik i professionel lærerpraksis. Med reference til Anne Marie Pahuus, der bygger på bl.a. Aristoteles, Kant, og Hannah Arendt, introduceres begrebet dømmekraft med udgangspunkt i den praktiske...

  16. Børs- og kapitalmarkedsret

    DEFF Research Database (Denmark)

    Schaumburg-Müller, Peer; Werlauff, Erik

    Værket giver et samlet billede af danske og EU-retlige forskrifter om regulerede værdipapirmarkeder. Det beskrives i dybden, hvordan det danske værdipapirmarked fungerer, og hvilke regelsæt der skal iagttages af et selskab, der bliver børsnoteret eller allerede er børsnoteret. Desuden behandles h...

  17. Elevers læring gennem undersøgelse og faglig læsning

    DEFF Research Database (Denmark)

    Negendahl, Kim; Daugbjerg, Peer

    2014-01-01

    Med afsæt i Prof. Jens Rasmussens (2013) argumenter for undervisningsdifferentiering vha. præstationsstandarder behandles differentiering af naturfagsundervisnings målsætning for alle skolens elever. Fokus vil være på læreres arbejde med undervisningsplaner og opstillede mål i forhold til undervi...

  18. Music as support and challenge

    DEFF Research Database (Denmark)

    Bonde, Lars Ole

    2010-01-01

    Første del af forskningsrapport om gruppemusikterapi med psykiatriske patienter i ambulant behandling. Metoden kaldes "Musiklytning og indre billeder" og der anvendes klassisk musik med såvel støttende som udfordrende elementer. Den artikel opridser den teoretiske baggrund for anvendelsen af denne...

  19. Secondary care intervals before and after the introduction of urgent referral guidelines for suspected cancer in Denmark

    DEFF Research Database (Denmark)

    Larsen, Mette Bach; Hansen, Rikke Pilegaard; Hansen, Dorte Gilså

    2013-01-01

    på nationalt niveau spiller en rolle for hurtig udredning og iværksættelse af behandling for kræftsygdomme. Resultaterne er baseret på et retrospektivt populationsbaseret studie med data fra i alt 6518 kræftpatienter. Data blev indsamlet via spørgeskemaer, som blev udfyldt af patienternes...

  20. Pædagogik på kanten

    DEFF Research Database (Denmark)

    Andersen, Frans Ørsted

    Bogen behandler intensive læringsforløb for udsatte elever, især drenge, men også en del piger. Der er tale om forløb og emner, som jeg selv forsker i, bl.a. Drengeakademiet, rollespilsefterskolen, Cooperative Learning og Fremtidens Undervisningsfacilitet. Desuden omtales en række tilsvarende pro...