WorldWideScience

Sample records for affymetrix one-cycle two-cycle

  1. Two Quantum Polytropic Cycles

    Science.gov (United States)

    Arias-Hernández, L. A.; Morales-Serrano, A. F.

    2002-11-01

    In this work we follow the Bender et al paper [1] to study the quantum analogues of the Stirling and Ericsson polytropic cycles. In the context of the classical thermodynamics, the Stirling and Ericsson cycles correspond to reversible heat engines with two isothermal processes joined by two polytropic branches which occur in a device called regenerator. If this device is an ideal one, the efficiency of these cycles is the Carnot efficiency. Here, we introduce the quantum analogues of the Stirling and Ericsson cycles, the first one based on a double square potential well with a finite potential barrier, since in this system the tunnel effect could be the analogue to the regeneration classical process, therefore the isochoric quantum branches would really correspond to an internal energy storage, and the last one with an unknown system where the isobaric quantum processes don't induce changes in its quantum state. With these systems the quantum engines have cycles consisting of polytropic and isothermal quantum processes analogues to the corresponding classical processes. We show that in both cases the quantum cycles have an efficiency given by ηCQM = 1 - EC/EH, which is the same expression for the quantum analogue of the Carnot cycle studied by Bender.

  2. Fuel cycle math - part one

    International Nuclear Information System (INIS)

    Anon.

    1992-01-01

    This article is Part One of a two-part article that reviews some of the numbers associated with the nuclear fuel cycle. The contents of Part One include: composition of the element uranium, considering atomic mass and weight-percent of the isotopes; uranium in the ground, including ore grades; mining, with dilution factors and recovery rates; ore sorting, including concentration factors; and uranium recovery. No financial information is presented in either Part One or Part Two

  3. A New, Highly Improved Two-Cycle Engine

    Science.gov (United States)

    Wiesen, Bernard

    2008-01-01

    The figure presents a cross-sectional view of a supercharged, variable-compression, two-cycle, internal-combustion engine that offers significant advantages over prior such engines. The improvements are embodied in a combination of design changes that contribute synergistically to improvements in performance and economy. Although the combination of design changes and the principles underlying them are complex, one of the main effects of the changes on the overall engine design is reduced (relative to prior two-cycle designs) mechanical complexity, which translates directly to reduced manufacturing cost and increased reliability. Other benefits include increases in the efficiency of both scavenging and supercharging. The improvements retain the simplicity and other advantages of two-cycle engines while affording increases in volumetric efficiency and performance across a wide range of operating conditions that, heretofore have been accessible to four-cycle engines but not to conventionally scavenged two-cycle ones, thereby increasing the range of usefulness of the two-cycle engine into all areas now dominated by the four-cycle engine. The design changes and benefits are too numerous to describe here in detail, but it is possible to summarize the major improvements: Reciprocating Shuttle Inlet Valve The entire reciprocating shuttle inlet valve and its operating gear is constructed as a single member. The shuttle valve is actuated in a lost-motion arrangement in which, at the ends of its stroke, projections on the shuttle valve come to rest against abutments at the ends of grooves in a piston skirt. This shuttle-valve design obviates the customary complex valve mechanism, actuated from an engine crankshaft or camshaft, yet it is effective with every type of two-cycle engine, from small high-speed single cylinder model engines, to large low-speed multiple cylinder engines.

  4. Two cycles of plasma rich in growth factors (PRGF-Endoret) intra-articular injections improve stiffness and activities of daily living but not pain compared to one cycle on patients with symptomatic knee osteoarthritis.

    Science.gov (United States)

    Vaquerizo, Víctor; Padilla, Sabino; Aguirre, José Javier; Begoña, Leire; Orive, Gorka; Anitua, Eduardo

    2017-05-19

    To assess the clinical efficacy and safety of a treatment based on one cycle versus two cycles of intra-articular injections of plasma rich in growth factors (PRGF-Endoret) on patients with knee osteoarthritis (OA). Ninety patients with knee OA were included and evaluated. A total of 48 patients received one cycle (OC group) (3 injections on a weekly basis), while 42 patients received two cycles of PRGF-Endoret (TC group) spaced 6 months between them. Patients were evaluated with LEQUESNE and WOMAC scores before treatment and after 48 weeks. Safety assessment was also performed. A significant reduction of all assessed outcome measures was shown for both groups at 48 weeks compared with baseline values (P PRGF did not show a significantly higher pain reduction compared with one cycle treatment. However, two cycles of PRGF showed a significant improvement in WOMAC stiffness, LEQUESNE MCD, LEQUESNE ADV and LEQUESNE global subscales. Therefore, patients treated with two cycles present an improvement in quality of life. II.

  5. Bifurcations of heterodimensional cycles with two saddle points

    Energy Technology Data Exchange (ETDEWEB)

    Geng Fengjie [School of Information Technology, China University of Geosciences (Beijing), Beijing 100083 (China)], E-mail: gengfengjie_hbu@163.com; Zhu Deming [Department of Mathematics, East China Normal University, Shanghai 200062 (China)], E-mail: dmzhu@math.ecnu.edu.cn; Xu Yancong [Department of Mathematics, East China Normal University, Shanghai 200062 (China)], E-mail: yancongx@163.com

    2009-03-15

    The bifurcations of 2-point heterodimensional cycles are investigated in this paper. Under some generic conditions, we establish the existence of one homoclinic loop, one periodic orbit, two periodic orbits, one 2-fold periodic orbit, and the coexistence of one periodic orbit and heteroclinic loop. Some bifurcation patterns different to the case of non-heterodimensional heteroclinic cycles are revealed.

  6. Bifurcations of heterodimensional cycles with two saddle points

    International Nuclear Information System (INIS)

    Geng Fengjie; Zhu Deming; Xu Yancong

    2009-01-01

    The bifurcations of 2-point heterodimensional cycles are investigated in this paper. Under some generic conditions, we establish the existence of one homoclinic loop, one periodic orbit, two periodic orbits, one 2-fold periodic orbit, and the coexistence of one periodic orbit and heteroclinic loop. Some bifurcation patterns different to the case of non-heterodimensional heteroclinic cycles are revealed.

  7. Bipolar mood cycles and lunar tidal cycles.

    Science.gov (United States)

    Wehr, T A

    2018-04-01

    In 17 patients with rapid cycling bipolar disorder, time-series analyses detected synchronies between mood cycles and three lunar cycles that modulate the amplitude of the moon's semi-diurnal gravimetric tides: the 14.8-day spring-neap cycle, the 13.7-day declination cycle and the 206-day cycle of perigee-syzygies ('supermoons'). The analyses also revealed shifts among 1:2, 1:3, 2:3 and other modes of coupling of mood cycles to the two bi-weekly lunar cycles. These shifts appear to be responses to the conflicting demands of the mood cycles' being entrained simultaneously to two different bi-weekly lunar cycles with slightly different periods. Measurements of circadian rhythms in body temperature suggest a biological mechanism through which transits of one of the moon's semi-diurnal gravimetric tides might have driven the patients' bipolar cycles, by periodically entraining the circadian pacemaker to its 24.84-h rhythm and altering the pacemaker's phase-relationship to sleep in a manner that is known to cause switches from depression to mania.

  8. Potential benefits of saturation cycle with two-phase refrigerant injection

    International Nuclear Information System (INIS)

    Lee, Hoseong; Hwang, Yunho; Radermacher, Reinhard; Chun, Ho-Hwan

    2013-01-01

    In this paper, a saturation cycle is proposed to enhance a vapor compression cycle performance by reducing thermodynamic losses associated with single phase gas compression and isenthalpic expansion. In order to approach the saturation cycle, a two-phase refrigerant injection technique is applied to the multi-stage cycle. This multi-stage cycle with different options is modeled, and its performance is evaluated under ASHRAE standard operating conditions for air conditioning systems. Moreover, the two-phase refrigerant injection cycle is compared with the typical vapor injection cycle which is utilizing the internal heat exchanger or the flash tank. Low GWP refrigerants are applied to this two-phase refrigerant injection cycle. In terms of the COP and its improvement, R123 has a higher potential than any other refrigerants in the multi-stage cycle. Lastly, practical ideas realizing the saturation cycle are discussed such as multi-stage phase separator, phase separator with helical structure inside, and injection location of the compressor. -- Highlights: • A saturation cycle is proposed to enhance the vapor compression cycle performance. • Two-phase refrigerant injection technique is applied to the multi-stage cycle. • Modeling results of the proposed cycle show the significant performance improvement. • Low GWP refrigerants are applied and R123 shows the highest performance. • New parameters, α and ε, are used to show the potential of the saturation cycle

  9. Single generation cycles and delayed feedback cycles are not separate phenomena.

    Science.gov (United States)

    Pfaff, T; Brechtel, A; Drossel, B; Guill, C

    2014-12-01

    We study a simple model for generation cycles, which are oscillations with a period of one or a few generation times of the species. The model is formulated in terms of a single delay-differential equation for the population density of an adult stage, with recruitment to the adult stage depending on the intensity of competition during the juvenile phase. This model is a simplified version of a group of models proposed by Gurney and Nisbet, who were the first to distinguish between single-generation cycles and delayed-feedback cycles. According to these authors, the two oscillation types are caused by different mechanisms and have periods in different intervals, which are one to two generation times for single-generation cycles and two to four generation times for delayed-feedback cycles. By abolishing the strict coupling between the maturation time and the time delay between competition and its effect on the population dynamics, we find that single-generation cycles and delayed-feedback cycles occur in the same model version, with a gradual transition between the two as the model parameters are varied over a sufficiently large range. Furthermore, cycle periods are not bounded to lie within single octaves. This implies that a clear distinction between different types of generation cycles is not possible. Cycles of all periods and even chaos can be generated by varying the parameters that determine the time during which individuals from different cohorts compete with each other. This suggests that life-cycle features in the juvenile stage and during the transition to the adult stage are important determinants of the dynamics of density limited populations. Copyright © 2014 Elsevier Inc. All rights reserved.

  10. Fuel cycle math - part two

    International Nuclear Information System (INIS)

    Anon.

    1992-01-01

    This article is Part 2 of a two part series on simple mathematics associated with the nuclear fuel cycle. While not addressing any of the financial aspects of the fuel cycle, this article does discuss the following: conversion between English and metric systems; uranium content expressed in equivalent forms, such as U3O8, and the method of determining these equivalencies; the uranium conversion process, considering different input and output compounds; and the enrichment process, including feed, tails, and product assays, as well as SWU and feed requirements

  11. Approximating maximum weight cycle covers in directed graphs with weights zero and one

    NARCIS (Netherlands)

    Bläser, Markus; Manthey, Bodo

    2005-01-01

    A cycle cover of a graph is a spanning subgraph each node of which is part of exactly one simple cycle. A $k$-cycle cover is a cycle cover where each cycle has length at least $k$. Given a complete directed graph with edge weights zero and one, Max-$k$-DCC(0, 1) is the problem of finding a k-cycle

  12. Cumulative live birth rates after one ART cycle including all subsequent frozen-thaw cycles in 1050 women

    DEFF Research Database (Denmark)

    Toftager, M; Bogstad, J; Løssl, K

    2017-01-01

    birth increases. There are no previous randomized controlled trials (RCTs) comparing CLBRs in GnRH-antagonist versus GnRH-agonist protocols. Previous studies on CLBR are either retrospective cohort studies including multiple fresh cycles or RCTs comparing single embryo transfer (SET) with double embryo...... transfer (DET). STUDY DESIGN, SIZE, DURATION: CLBR was a secondary outcome in a Phase IV, dual-center, open-label, RCT including 1050 women allocated to a short GnRH-antagonist or a long GnRH-agonist protocol in a 1:1 ratio over a 5-year period using a web-based concealed randomization code. The minimum...... follow-up time from the first IVF cycle was 2 years. The aim was to compare CLBR between the two groups following utilization of all fresh and frozen embryos from the first ART cycle. PARTICIPANTS/MATERIALS, SETTING, METHODS: All women referred for their first ART cycle at two public fertility clinics...

  13. Final Report on Two-Stage Fast Spectrum Fuel Cycle Options

    International Nuclear Information System (INIS)

    Yang, Won Sik; Lin, C. S.; Hader, J. S.; Park, T. K.; Deng, P.; Yang, G.; Jung, Y. S.; Kim, T. K.; Stauff, N. E.

    2016-01-01

    This report presents the performance characteristics of two ''two-stage'' fast spectrum fuel cycle options proposed to enhance uranium resource utilization and to reduce nuclear waste generation. One is a two-stage fast spectrum fuel cycle option of continuous recycle of plutonium (Pu) in a fast reactor (FR) and subsequent burning of minor actinides (MAs) in an accelerator-driven system (ADS). The first stage is a sodium-cooled FR fuel cycle starting with low-enriched uranium (LEU) fuel; at the equilibrium cycle, the FR is operated using the recovered Pu and natural uranium without supporting LEU. Pu and uranium (U) are co-extracted from the discharged fuel and recycled in the first stage, and the recovered MAs are sent to the second stage. The second stage is a sodium-cooled ADS in which MAs are burned in an inert matrix fuel form. The discharged fuel of ADS is reprocessed, and all the recovered heavy metals (HMs) are recycled into the ADS. The other is a two-stage FR/ADS fuel cycle option with MA targets loaded in the FR. The recovered MAs are not directly sent to ADS, but partially incinerated in the FR in order to reduce the amount of MAs to be sent to the ADS. This is a heterogeneous recycling option of transuranic (TRU) elements

  14. Final Report on Two-Stage Fast Spectrum Fuel Cycle Options

    Energy Technology Data Exchange (ETDEWEB)

    Yang, Won Sik [Purdue Univ., West Lafayette, IN (United States); Lin, C. S. [Purdue Univ., West Lafayette, IN (United States); Hader, J. S. [Purdue Univ., West Lafayette, IN (United States); Park, T. K. [Purdue Univ., West Lafayette, IN (United States); Deng, P. [Purdue Univ., West Lafayette, IN (United States); Yang, G. [Purdue Univ., West Lafayette, IN (United States); Jung, Y. S. [Purdue Univ., West Lafayette, IN (United States); Kim, T. K. [Argonne National Lab. (ANL), Argonne, IL (United States); Stauff, N. E. [Argonne National Lab. (ANL), Argonne, IL (United States)

    2016-01-30

    This report presents the performance characteristics of twotwo-stage” fast spectrum fuel cycle options proposed to enhance uranium resource utilization and to reduce nuclear waste generation. One is a two-stage fast spectrum fuel cycle option of continuous recycle of plutonium (Pu) in a fast reactor (FR) and subsequent burning of minor actinides (MAs) in an accelerator-driven system (ADS). The first stage is a sodium-cooled FR fuel cycle starting with low-enriched uranium (LEU) fuel; at the equilibrium cycle, the FR is operated using the recovered Pu and natural uranium without supporting LEU. Pu and uranium (U) are co-extracted from the discharged fuel and recycled in the first stage, and the recovered MAs are sent to the second stage. The second stage is a sodium-cooled ADS in which MAs are burned in an inert matrix fuel form. The discharged fuel of ADS is reprocessed, and all the recovered heavy metals (HMs) are recycled into the ADS. The other is a two-stage FR/ADS fuel cycle option with MA targets loaded in the FR. The recovered MAs are not directly sent to ADS, but partially incinerated in the FR in order to reduce the amount of MAs to be sent to the ADS. This is a heterogeneous recycling option of transuranic (TRU) elements

  15. Are there two types of business cycles? a note on crisis detection

    Directory of Open Access Journals (Sweden)

    Robert Pater

    2014-12-01

    Full Text Available Business cycles are highly irregular fluctuations in economic activity. This article attempts to determine whether there are some properties of business cycles that can make them look more regular. This is done by analysing business cycle dynamics, especially by employing and adjusting to contemporary business cycle analysis the theories of growth cycles and classical cycles. The non-homogeneity of business cycles is surveyed in theory and practice with use of ad hoc filtering, spectral analysis and unobserved components models. With their use business cycles are extracted. Several macroeconomic indicators for 32 economies are analysed to draw up additional characteristics of contemporary business cycles. The author proposes that fluctuations in economic activity lasting 8-19 quarters should be called ‘growth cycles’ and those lasting 20-40 quarters – ‘classical cycles’. The value added of this article is the consideration of the two different type of cycles in light of the same methods of extraction, while to date they have been thought of as the ones that can be analysed with use of different methods of extraction. Another innovation is comparison of the cyclicality of different macroeconomic indicators from the point of view of the two types of cycles, while to date they have been analysed in the light of a single business cycle. In the article it is shown that dividing business cycles into such defined classical cycles and growth cycles enables us to understand the differences between the cyclicality of various macroeconomic aggregates and countries. It also enables us to distinguish between smaller downturns and severe recessions. Another conclusion is that the duration of contemporary business cycles around the world closes in a range of 2 to 10 years.

  16. Thermomechanical cycling and two-way memory effect induced in Cu-Zn-Al

    International Nuclear Information System (INIS)

    Pons, J.

    1999-01-01

    The two-way shape memory effect (TWME) has been induced by thermomechanical cycling in Cu-Zn-Al alloys using a dedicated hydraulic mechanical testing soft machine with complete computer control of force, elongation and temperature. The results concerning single crystals (composition Cu-16.9 wt.% Zn-7.7 wt.% Al, nominal M s of 273 K) and polycrystals (Cu-15.8 wt.% Zn-8.3 wt.% Al, nominal M s of 230 K, mean grain size of 1 mm) are reported for two training protocols (sequence of one thermomechanical cycle of education followed by one stress free thermal cycle to check the TWME or twenty consecutive thermomechanical cycles followed by one or two checking thermal cycles). The capacity of the trained specimen for producing work under an antagonist compressive stress is also studied and the behaviour of the deformation of the specimen under such a condition at different temperatures is analysed in terms of a competition between the contributions of the different variants: trained variants with an intrinsic deformation in the direction of the tensile stress of the training process, trained variants with an intrinsic deformation which is not well orientated with respect to this direction (in the polycrystal) and new variants with an intrinsic deformation in the direction of the compressive stress which can replace the educated variants. (orig.)

  17. Two-stage double-effect ammonia/lithium nitrate absorption cycle

    International Nuclear Information System (INIS)

    Ventas, R.; Lecuona, A.; Vereda, C.; Legrand, M.

    2016-01-01

    Highlights: • A two stage double effect cycle with NH3-LiNO3 is proposed. • The cycle operates at lower pressures than conventional. • Adiabatic absorber offers better performance than the diabatic version. • Evaporator external inlet temperatures higher than −10 °C avoids crystallization. • Maximum COP is 1.25 for driving water inlet temperature of 100 C. - Abstract: The two-stage configuration of a double-effect absorption cycle using ammonia/lithium nitrate as working fluid is studied by means of a thermodynamic model. The maximum pressure of this cycle configuration is the same as the single-effect cycle, up to 15.8 bars, being an advantage over the double-effect conventional configuration with three pressure levels that exhibits much higher maximum pressure. The performance of the cycle and the limitation imposed by crystallization of the working fluid is determined for both adiabatic and diabatic absorber cycles. Both cycles offer similar COP; however the adiabatic variant shows a larger margin against crystallization. This cycle can produce cold for external inlet evaporator temperatures down to −10 °C, but for this limit the crystallization could happen at high inlet generator temperatures. The maximum COP can be 1.25 for an external inlet generator temperature of 100 °C. This cycle shows a better COP than a typical double effect cycle with in-parallel configuration for the range of the moderate temperatures under study and using the same working fluid. Comparisons with double effect cycles using H_2O/LiBr and NH_3/H_2O as working fluids are also offered, highlighting the present configurations advantages regarding COP, evaporation and condensation temperatures as well as crystallization.

  18. Rank one chaos in a class of planar systems with heteroclinic cycle.

    Science.gov (United States)

    Chen, Fengjuan; Han, Maoan

    2009-12-01

    In this paper, we study rank one chaos in a class of planar systems with heteroclinic cycle. We first find a stable limit cycle inside the heteroclinic cycle. We then add an external periodic forcing to create rank one chaos. We follow a step-by-step procedure guided by the theory of rank one chaos to find experimental evidence of strange attractors with Sinai, Ruelle, and Bowen measures.

  19. A Thermodynamic Analysis of Two Competing Mid-Sized Oxyfuel Combustion Combined Cycles

    Directory of Open Access Journals (Sweden)

    Egill Thorbergsson

    2016-01-01

    Full Text Available A comparative analysis of two mid-sized oxyfuel combustion combined cycles is performed. The two cycles are the semiclosed oxyfuel combustion combined cycle (SCOC-CC and the Graz cycle. In addition, a reference cycle was established as the basis for the analysis of the oxyfuel combustion cycles. A parametric study was conducted where the pressure ratio and the turbine entry temperature were varied. The layout and the design of the SCOC-CC are considerably simpler than the Graz cycle while it achieves the same net efficiency as the Graz cycle. The fact that the efficiencies for the two cycles are close to identical differs from previously reported work. Earlier studies have reported around a 3% points advantage in efficiency for the Graz cycle, which is attributed to the use of a second bottoming cycle. This additional feature is omitted to make the two cycles more comparable in terms of complexity. The Graz cycle has substantially lower pressure ratio at the optimum efficiency and has much higher power density for the gas turbine than both the reference cycle and the SCOC-CC.

  20. The Krebs Uric Acid Cycle: A Forgotten Krebs Cycle.

    Science.gov (United States)

    Salway, Jack G

    2018-05-25

    Hans Kornberg wrote a paper entitled 'Krebs and his trinity of cycles' commenting that every school biology student knows of the Krebs cycle, but few know that Krebs discovered two other cycles. These are (i) the ornithine cycle (urea cycle), (ii) the citric acid cycle (tricarboxylic acid or TCA cycle), and (iii) the glyoxylate cycle that was described by Krebs and Kornberg. Ironically, Kornberg, codiscoverer of the 'glyoxylate cycle', overlooked a fourth Krebs cycle - (iv) the uric acid cycle. Copyright © 2018 Elsevier Ltd. All rights reserved.

  1. Qualitative analysis on cycle commuting in two cities with different cycling environments and policies

    OpenAIRE

    Lois, David; Universidad Nacional de Educación a Distancia (UNED); López-Sáez, Mercedes; Facultad de Psicología. Universidad Nacional de Educación a Distancia (UNED).; Rondinella, Gianni; Centro de Investigación del Transporte (TRANSyT). Universidad Politécnica de Madrid (UPM).

    2016-01-01

    This work presents the results of a qualitative study of the rating of the bicycle as the transport mode to travel to the workplace. Twenty-one semi-structured interviews were performed in two Spanish cities, Vitoria-Gasteiz and Madrid, with different cycling infrastructures and percentages of bicycle usage. The results were categorized and interpreted within the framework of the theory of planned behavior (Ajzen, 1991). The results indicate that the bicycle is considered a reliable and flexi...

  2. Differential gene expression in anterior pituitary glands from anestrous and cycling postpartum beef cows

    Science.gov (United States)

    Oligionucleotide microarrays (GeneChip Bovine Genome Arrays, Affymetrix Inc., Santa Clara, CA) were used to evaluate gene expression profiles in anterior pituitary glands collected from 4 anestrous and 4 cycling postpartum primiparous beef cows to provide insight into genes associated with transitio...

  3. Two-way shape memory effect induced by repetitive compressive loading cycles

    International Nuclear Information System (INIS)

    Kim, Hyun-Chul; Yoo, Young-Ik; Lee, Jung-Ju

    2009-01-01

    The NiTi alloy can be trained by repetitive loading or heating cycles. As a result of the training, a two-way shape memory effect (TWSME) can be induced. Considerable research has been reported regarding the TWSME trained by tensile loading. However, the TWSME trained by compressive loading has not been investigated nearly as much. In this paper, the TWSME is induced by compressive loading cycles and the two-way shape memory strain is evaluated by using two types of specimen: a solid cylinder type and a tube type. The TWSME trained by compressive loading is different from that trained by tensile loading owing to the severe tension/compression asymmetry as described in previous research. After repetitive compressive loading cycles, strain variation upon cooling is observed, and this result proves that the TWSME is induced by compressive loading cycles. By performing compressive loading cycles, plastic deformation in NiTi alloy occurs more than for tensile loading cycles, which brings about the appearance of TWSME. It can be said that the TWSME is induced by compressive loading cycles more easily. The two-way shape memory strain increases linearly as the maximum strain of compressive loading cycles increases, regardless of the shape and the size of the NiTi alloy; this two-way shape memory strain then shows a tendency towards saturation after some repeated cycles

  4. Comparison for thorium fuel cycle facilities of two different capacities for implementation of safeguards

    International Nuclear Information System (INIS)

    Gangotra, Suresh; Grover, R.B.; Ramakumar, K.L.

    2013-01-01

    Highlights: • Facilities for implementation of safeguards for thorium fuel cycle have been compared. • Two concepts have been compared. • In one concept, the facilities are designed in hub and spoke concept. • In second concept the facilities are designed as self-contained concept. • The comparison is done on a number of factors, which affect safeguardability and proliferation resistance. -- Abstract: Thorium based nuclear fuel cycle has many attractive features, its inherent proliferation resistance being one of them. This is due to the presence of high energy gamma emitting daughter products of U 232 associated with U 233 . This high energy gamma radiation also poses challenges in nuclear material accounting. A typical thorium fuel cycle facility has a number of plants including a fuel fabrication plant for initial and equilibrium core, a reprocessed U 233 fuel fabrication plant, a reprocessing plant, a fuel assembly/disassembly plant and associated waste handling and management plants. A thorium fuel cycle facility can be set up to serve reactors at a site. Alternatively, one can follow a hub and spoke approach with a large thorium fuel cycle facility acting as a hub, catering to the requirements of reactors at several sites as spokes. These two concepts have their respective merits and shortcomings in terms of engineering and economics. The present paper is aimed at comparing the merits and challenges for implementation of safeguards on the two concepts viz. a large fuel cycle hub catering to reactors at several sites versus a small fuel cycle facility dedicated to reactors at a single site

  5. Comparison for thorium fuel cycle facilities of two different capacities for implementation of safeguards

    Energy Technology Data Exchange (ETDEWEB)

    Gangotra, Suresh, E-mail: sgangotra@yahoo.co.in; Grover, R.B.; Ramakumar, K.L.

    2013-09-15

    Highlights: • Facilities for implementation of safeguards for thorium fuel cycle have been compared. • Two concepts have been compared. • In one concept, the facilities are designed in hub and spoke concept. • In second concept the facilities are designed as self-contained concept. • The comparison is done on a number of factors, which affect safeguardability and proliferation resistance. -- Abstract: Thorium based nuclear fuel cycle has many attractive features, its inherent proliferation resistance being one of them. This is due to the presence of high energy gamma emitting daughter products of U{sup 232} associated with U{sup 233}. This high energy gamma radiation also poses challenges in nuclear material accounting. A typical thorium fuel cycle facility has a number of plants including a fuel fabrication plant for initial and equilibrium core, a reprocessed U{sup 233} fuel fabrication plant, a reprocessing plant, a fuel assembly/disassembly plant and associated waste handling and management plants. A thorium fuel cycle facility can be set up to serve reactors at a site. Alternatively, one can follow a hub and spoke approach with a large thorium fuel cycle facility acting as a hub, catering to the requirements of reactors at several sites as spokes. These two concepts have their respective merits and shortcomings in terms of engineering and economics. The present paper is aimed at comparing the merits and challenges for implementation of safeguards on the two concepts viz. a large fuel cycle hub catering to reactors at several sites versus a small fuel cycle facility dedicated to reactors at a single site.

  6. Assessing Cycling Participation in Australia

    Directory of Open Access Journals (Sweden)

    Chris Rissel

    2013-01-01

    Full Text Available Planning and evaluating cycling programs at a national or state level requires accurate measures of cycling participation. However, recent reports of cycling participation have produced very different estimates. This paper examines the reported rates of cycling in five recent population surveys of cycling. Three surveys (one national and two from Sydney asking respondents when they last rode a bicycle generated cycling participation (cycled in the past year estimates of 29.7%, 34.1% and 28.9%. Two other national surveys which asked participants to recall (unprompted any physical activity done for exercise, recreation or sport in the previous 12 months, estimated cycling in the past year as 11.1% and 6.5%. While unprompted recall of cycling as a type of physical activity generates lower estimates of cycling participation than specific recall questions, both assessment approaches produced similar patterns of cycling by age and sex with both approaches indicating fewer women and older adults cycling. The different question styles most likely explain the substantial discrepancies between the estimates of cycling participation. Some differences are to be expected due to sampling variability, question differences, and regional variation in cycling.

  7. Centriole maturation requires regulated Plk1 activity during two consecutive cell cycles.

    Science.gov (United States)

    Kong, Dong; Farmer, Veronica; Shukla, Anil; James, Jana; Gruskin, Richard; Kiriyama, Shigeo; Loncarek, Jadranka

    2014-09-29

    Newly formed centrioles in cycling cells undergo a maturation process that is almost two cell cycles long before they become competent to function as microtubule-organizing centers and basal bodies. As a result, each cell contains three generations of centrioles, only one of which is able to form cilia. It is not known how this long and complex process is regulated. We show that controlled Plk1 activity is required for gradual biochemical and structural maturation of the centrioles and timely appendage assembly. Inhibition of Plk1 impeded accumulation of appendage proteins and appendage formation. Unscheduled Plk1 activity, either in cycling or interphase-arrested cells, accelerated centriole maturation and appendage and cilia formation on the nascent centrioles, erasing the age difference between centrioles in one cell. These findings provide a new understanding of how the centriole cycle is regulated and how proper cilia and centrosome numbers are maintained in the cells.

  8. Performance analysis of a potassium-steam two stage vapour cycle

    International Nuclear Information System (INIS)

    Mitachi, Kohshi; Saito, Takeshi

    1983-01-01

    It is an important subject to raise the thermal efficiency in thermal power plants. In present thermal power plants which use steam cycle, the plant thermal efficiency has already reached 41 to 42 %, steam temperature being 839 K, and steam pressure being 24.2 MPa. That is, the thermal efficiency in a steam cycle is facing a limit. In this study, analysis was made on the performance of metal vapour/steam two-stage Rankine cycle obtained by combining a metal vapour cycle with a present steam cycle. Three different combinations using high temperature potassium regenerative cycle and low temperature steam regenerative cycle, potassium regenerative cycle and steam reheat and regenerative cycle, and potassium bleed cycle and steam reheat and regenerative cycle were systematically analyzed for the overall thermal efficiency, the output ratio and the flow rate ratio, when the inlet temperature of a potassium turbine, the temperature of a potassium condenser, and others were varied. Though the overall thermal efficiency was improved by lowering the condensing temperature of potassium vapour, it is limited by the construction because the specific volume of potassium in low pressure section increases greatly. In the combinatipn of potassium vapour regenerative cycle with steam regenerative cycle, the overall thermal efficiency can be 58.5 %, and also 60.2 % if steam reheat and regenerative cycle is employed. If a cycle to heat steam with the bled vapor out of a potassium vapour cycle is adopted, the overall thermal efficiency of 63.3 % is expected. (Wakatsuki, Y.)

  9. The hybrid two stage anticlockwise cycle for ecological energy conversion

    Directory of Open Access Journals (Sweden)

    Cyklis Piotr

    2016-01-01

    Full Text Available The anticlockwise cycle is commonly used for refrigeration, air conditioning and heat pumps applications. The application of refrigerant in the compression cycle is within the temperature limits of the triple point and the critical point. New refrigerants such as 1234yf or 1234ze have many disadvantages, therefore natural refrigerants application is favourable. The carbon dioxide and water can be applied only in the hybrid two stages cycle. The possibilities of this solutions are shown for refrigerating applications, as well some experimental results of the adsorption-compression double stages cycle, powered with solar collectors are shown. As a high temperature cycle the adsorption system is applied. The low temperature cycle is the compression stage with carbon dioxide as a working fluid. This allows to achieve relatively high COP for low temperature cycle and for the whole system.

  10. Effect of two-step and one-step surface conditioning of glass ceramic on adhesion strength of orthodontic bracket and effect of thermo-cycling on adhesion strength.

    Science.gov (United States)

    Asiry, Moshabab A; AlShahrani, Ibrahim; Alaqeel, Samer M; Durgesh, Bangalore H; Ramakrishnaiah, Ravikumar

    2018-08-01

    The adhesion strength of orthodontic brackets bonded to dental glass ceramics was evaluated after ceramic surface was treated with two-step and one-step surface conditioning systems, and subjecting to thermo-cycling. A total of forty specimens were fabricated from silica based glass ceramic (lithium disilicate) by duplicating the buccal surface of maxillary first premolar. The specimens were randomly assigned to two experimental groups (n = 20), group one specimens were treated with two-step surface conditioning system (IPS ceramic etching gel™ and Monobond plus™) and group two specimens were treated with one-step surface conditioning system (Monobond etch and prime™). The surface roughness of the specimens after treatment with two-step and one-step surface conditioning system was measured using non-contact surface profilometer. Ten randomly selected specimens from each group were subjected to thermo-cycling and the remaining ten served as baseline. The shear bond strength of the specimens was measured using universal material testing machine. The adhesive remnant index score was calculated, and the results of surface roughness and bond strength were tabulated and subjected to analysis of variance and post hoc tukey's test at a significance level of p step conditioning system had higher surface roughness and bond strength than one-step conditioning system. The majority of the specimens treated with both two-step and one-step conditioned specimens showed adhesive failure after subjecting thermo-cycling. Traditional two-step conditioning provides better bond strength. The clinical importance of the study is that, the silane promoted adhesion significantly reduces on exposure to thermo-cycling. Copyright © 2018 Elsevier Ltd. All rights reserved.

  11. KOH concentration effect on cycle life of nickel-hydrogen cells. III - Cycle life test

    Science.gov (United States)

    Lim, H. S.; Verzwyvelt, S. A.

    1988-01-01

    A cycle life test of Ni/H2 cells containing electrolytes of various KOH concentrations and a sintered type nickel electrode was carried out at 23 C using a 45 min accelerated low earth orbit (LEO) cycle regime at 80 percent depth of discharge. One of three cells containing 26 percent KOH has achieved over 28,000 cycles, and the other two 19,000 cycles, without a sign of failure. Two other cells containing 31 percent KOH electrolyte, which is the concentration presently used in aerospace cells, failed after 2,979 and 3,620 cycles. This result indicates that the cycle life of the present type of Ni/H2 cells may be extended by a factor of 5 to 10 simply by lowering the KOH concentration. Long cycle life of a Ni/H2 battery at high depth-of-discharge operation is desired, particularly for an LEO spacecraft application. Typically, battery life of about 30,000 cycles is required for a five year mission in an LEO. Such a cycle life with presently available cells can be assured only at a very low depth-of-discharge operation. Results of testing already show that the cycle life of an Ni/H2 cell is tremendously improved by simply using an electrolyte of low KOH concentration.

  12. Analytical investigation of one-dimensional Rydberg atoms interacting with half-cycle pulses

    International Nuclear Information System (INIS)

    Bersons, I.; Veilande, R.

    2004-01-01

    Classical, quantum-mechanical, and semiclassical expressions for the transition probability in one-dimensional Rydberg atom irradiated by short half-cycle pulse are derived and compared. The simple formulas obtained for excitation of Rydberg atom by two time delayed weak half-cycle pulses reproduce well the experimental data and the solutions of time-dependent Schroedinger equation. When the transferred momenta are stronger and positive, the transition probabilities exhibit fast oscillations with time delay between the pulses. The classical transition probability is constant in time. For negative transferred momenta a focusing phenomenon is observed, and there is a region in time delay, where the transition probabilities oscillate with the Kepler period

  13. Alternative ORC bottoming cycles FOR combined cycle power plants

    International Nuclear Information System (INIS)

    Chacartegui, R.; Sanchez, D.; Munoz, J.M.; Sanchez, T.

    2009-01-01

    In this work, low temperature Organic Rankine Cycles are studied as bottoming cycle in medium and large scale combined cycle power plants. The analysis aims to show the interest of using these alternative cycles with high efficiency heavy duty gas turbines, for example recuperative gas turbines with lower gas turbine exhaust temperatures than in conventional combined cycle gas turbines. The following organic fluids have been considered: R113, R245, isobutene, toluene, cyclohexane and isopentane. Competitive results have been obtained for toluene and cyclohexane ORC combined cycles, with reasonably high global efficiencies. The paper is structured in four main parts. A review of combined cycle and ORC cycle technologies is presented, followed by a thermodynamic analysis of combined cycles with commercial gas turbines and ORC low temperature bottoming cycles. Then, a parametric optimization of an ORC combined cycle plant is performed in order to achieve a better integration between these two technologies. Finally, some economic considerations related to the use of ORC in combined cycles are discussed.

  14. Life cycle assessment of two dwellings: one in Spain, a developed country, and one in Colombia, a country under development.

    Science.gov (United States)

    Ortiz-Rodríguez, Oscar; Castells, Francesc; Sonnemann, Guido

    2010-05-15

    The main objective of this paper is to study and quantify the differences in energy consumption and environmental impacts of two dwellings during the full building life cycle: one in Spain, a developed country, and one in Colombia, a country under development. In both scenarios, we assessed the construction, use and end-of-life phases. Results show that the use phase in the Pamplona house (Colombia) represents a lower percentage for all impacts in the total than in the Barcelona house (Spain). The findings of this study showed that the difference in consumption in Colombia and Spanish dwellings analysed is not only due to the variation in results for bio-climatic differences but also because of the consumption habits in each country. The importance of consumption habits of citizens and the need to decouple socio-economic development from energy consumption are sought for achieving sustainability from a life cycle perspective. There is a crucial necessity to provide satisfaction to basic needs and comfort requirements of population with reasonable and sustainable energy consumption. Then, the type of standard dwelling varies substantially depending on the geographic location where it is built. Climate, technological, cultural, socio-economical differences clearly define the standard of a building in any context and in any region. However, the function is always the same, to provide protection and housing for its habitants. Copyright 2010 Elsevier B.V. All rights reserved.

  15. Cycling infrastructure for reducing cycling injuries in cyclists.

    Science.gov (United States)

    Mulvaney, Caroline A; Smith, Sherie; Watson, Michael C; Parkin, John; Coupland, Carol; Miller, Philip; Kendrick, Denise; McClintock, Hugh

    2015-12-10

    abstracts of papers obtained from searches to determine eligibility. Two review authors extracted data from the included trials and assessed the risk of bias. We carried out a meta-analysis using the random-effects model where at least three studies reported the same intervention and outcome. Where there were sufficient studies, as a secondary analysis we accounted for changes in cyclist exposure in the calculation of the rate ratios. We rated the quality of the evidence as 'high', 'moderate', 'low' or 'very low' according to the GRADE approach for the installation of cycle routes and networks. We identified 21 studies for inclusion in the review: 20 controlled before-after (CBA) studies and one interrupted time series (ITS) study. These evaluated a range of infrastructure including cycle lanes, advanced stop lines, use of colour, cycle tracks, cycle paths, management of the road network, speed management, cycle routes and networks, roundabout design and packages of measures. No studies reported medically-attended or self-reported injuries. There was no evidence that cycle lanes reduce the rate of cycle collisions (rate ratio 1.21, 95% CI 0.70 to 2.08). Taking into account cycle flow, there was no difference in collisions for cyclists using cycle routes and networks compared with cyclists not using cycle routes and networks (RR 0.40, 95% CI 0.15 to 1.05). There was statistically significant heterogeneity between the studies (I² = 75%, Chi² = 8.00 df = 2, P = 0.02) for the analysis adjusted for cycle flow. We judged the quality of the evidence regarding cycle routes and networks as very low and we are very uncertain about the estimate. These analyses are based on findings from CBA studies.From data presented narratively, the use of 20 mph speed restrictions in urban areas may be effective at reducing cyclist collisions. Redesigning specific parts of cycle routes that may be particularly busy or complex in terms of traffic movement may be beneficial to cyclists in terms of

  16. Simultaneous loading patterns optimization for two successive cycles of pressurized water reactors

    International Nuclear Information System (INIS)

    Yamamoto, Akio; Sugimura, Erina; Kitamura, Yasunori; Yamane, Yoshihiro

    2004-01-01

    In this paper, simultaneous optimization is carried out for successive two cycles of pressurized water reactors. At first, a simplified problem of the simultaneous optimization was studied by assuming the batch-wise power sharing as independent variable, i.e., batch-wise power sharing was optimized without considering corresponding loading patterns. The optimization of the batch-wise power sharing was carried out for the conventional single cycle, the equilibrium cycle and the two successive (tandem) cycles. The analysis indicated that the tandem cycle optimization well reproduce that of the equilibrium cycle optimization, which is considered as a typical case of the true multicycle optimization. Next, simultaneous optimization of loading patterns for tandem cycles is carried out using the simulated annealing method. Since the design space of the tandem cycles optimization is much larger than that of the conventional single cycle optimization, the optimization condition (i.e., number of calculated patterns) are established through sensitivity study. The optimization results are compared with those obtained by the successive single cycle optimizations and it is clarified that the successive single cycle optimization well reproduces the optimization results obtained by the simultaneous optimization if objective functions are appropriately chosen. The above result will be encouraging for the current in-core optimization method since single cycle optimization is utilized due to limitation of computation time. (author)

  17. Nonparametric adaptive age replacement with a one-cycle criterion

    International Nuclear Information System (INIS)

    Coolen-Schrijner, P.; Coolen, F.P.A.

    2007-01-01

    Age replacement of technical units has received much attention in the reliability literature over the last four decades. Mostly, the failure time distribution for the units is assumed to be known, and minimal costs per unit of time is used as optimality criterion, where renewal reward theory simplifies the mathematics involved but requires the assumption that the same process and replacement strategy continues over a very large ('infinite') period of time. Recently, there has been increasing attention to adaptive strategies for age replacement, taking into account the information from the process. Although renewal reward theory can still be used to provide an intuitively and mathematically attractive optimality criterion, it is more logical to use minimal costs per unit of time over a single cycle as optimality criterion for adaptive age replacement. In this paper, we first show that in the classical age replacement setting, with known failure time distribution with increasing hazard rate, the one-cycle criterion leads to earlier replacement than the renewal reward criterion. Thereafter, we present adaptive age replacement with a one-cycle criterion within the nonparametric predictive inferential framework. We study the performance of this approach via simulations, which are also used for comparisons with the use of the renewal reward criterion within the same statistical framework

  18. Stable cycling in discrete-time genetic models.

    OpenAIRE

    Hastings, A

    1981-01-01

    Examples of stable cycling are discussed for two-locus, two-allele, deterministic, discrete-time models with constant fitnesses. The cases that cycle were found by using numerical techniques to search for stable Hopf bifurcations. One consequence of the results is that apparent cases of directional selection may be due to stable cycling.

  19. Stable cycling in discrete-time genetic models.

    Science.gov (United States)

    Hastings, A

    1981-11-01

    Examples of stable cycling are discussed for two-locus, two-allele, deterministic, discrete-time models with constant fitnesses. The cases that cycle were found by using numerical techniques to search for stable Hopf bifurcations. One consequence of the results is that apparent cases of directional selection may be due to stable cycling.

  20. The prefrontal oxygenation and ventilatory responses at start of one-legged cycling exercise have relation to central command.

    Science.gov (United States)

    Asahara, Ryota; Matsukawa, Kanji; Ishii, Kei; Liang, Nan; Endo, Kana

    2016-11-01

    When performing exercise arbitrarily, activation of central command should start before the onset of exercise, but when exercise is forced to start with cue, activation of central command should be delayed. We examined whether the in-advance activation of central command influenced the ventilatory response and reflected in the prefrontal oxygenation, by comparing the responses during exercise with arbitrary and cued start. The breath-by-breath respiratory variables and the prefrontal oxygenated-hemoglobin concentration (Oxy-Hb) were measured during one-legged cycling. Minute ventilation (V̇e) at the onset of arbitrary one-legged cycling was augmented to a greater extent than cued cycling, while end-tidal carbon dioxide tension (ETco 2 ) decreased irrespective of arbitrary or cued start. Symmetric increase in the bilateral prefrontal Oxy-Hb occurred before and at the onset of arbitrary one-legged cycling, whereas such an increase was absent with cued start. The time course and magnitude of the increased prefrontal oxygenation were not influenced by the extent of subjective rating of perceived exertion and were the same as those of the prefrontal oxygenation during two-legged cycling previously reported. Mental imagery or passive performance of the one-legged cycling increased V̇e and decreased ETco 2 Neither intervention, however, augmented the prefrontal Oxy-Hb. The changes in ETco 2 could not explain the prefrontal oxygenation response during voluntary or passive one-legged cycling. Taken together, it is likely that the in-advance activation of central command influenced the ventilatory response by enhancing minute ventilation at the onset of one-legged cycling exercise and reflected in the preexercise increase in the prefrontal oxygenation. Copyright © 2016 the American Physiological Society.

  1. The optimum intermediate pressure of two-stages vapor compression refrigeration cycle for Air-Conditioning unit

    Science.gov (United States)

    Ambarita, H.; Sihombing, H. V.

    2018-03-01

    Vapor compression cycle is mainly employed as a refrigeration cycle in the Air-Conditioning (AC) unit. In order to save energy, the Coefficient of Performance (COP) of the need to be improved. One of the potential solutions is to modify the system into multi-stages vapor compression cycle. The suitable intermediate pressure between the high and low pressures is one of the design issues. The present work deals with the investigation of an optimum intermediate pressure of two-stages vapor compression refrigeration cycle. Typical vapor compression cycle that is used in AC unit is taken into consideration. The used refrigerants are R134a. The governing equations have been developed for the systems. An inhouse program has been developed to solve the problem. COP, mass flow rate of the refrigerant and compressor power as a function of intermediate pressure are plotted. It was shown that there exists an optimum intermediate pressure for maximum COP. For refrigerant R134a, the proposed correlations need to be revised.

  2. Modelling of an air-cooled two-stage Rankine cycle for electricity production

    International Nuclear Information System (INIS)

    Liu, Bo

    2014-01-01

    This work considers a two stage Rankine cycle architecture slightly different from a standard Rankine cycle for electricity generation. Instead of expanding the steam to extremely low pressure, the vapor leaves the turbine at a higher pressure then having a much smaller specific volume. It is thus possible to greatly reduce the size of the steam turbine. The remaining energy is recovered by a bottoming cycle using a working fluid which has a much higher density than the water steam. Thus, the turbines and heat exchangers are more compact; the turbine exhaust velocity loss is lower. This configuration enables to largely reduce the global size of the steam water turbine and facilitate the use of a dry cooling system. The main advantage of such an air cooled two stage Rankine cycle is the possibility to choose the installation site of a large or medium power plant without the need of a large and constantly available water source; in addition, as compared to water cooled cycles, the risk regarding future operations is reduced (climate conditions may affect water availability or temperature, and imply changes in the water supply regulatory rules). The concept has been investigated by EDF R and D. A 22 MW prototype was developed in the 1970's using ammonia as the working fluid of the bottoming cycle for its high density and high latent heat. However, this fluid is toxic. In order to search more suitable working fluids for the two stage Rankine cycle application and to identify the optimal cycle configuration, we have established a working fluid selection methodology. Some potential candidates have been identified. We have evaluated the performances of the two stage Rankine cycles operating with different working fluids in both design and off design conditions. For the most acceptable working fluids, components of the cycle have been sized. The power plant concept can then be evaluated on a life cycle cost basis. (author)

  3. Evaluation of a combined cycle based on an HCCI (Homogenous Charge Compression Ignition) engine heat recovery employing two organic Rankine cycles

    International Nuclear Information System (INIS)

    Khaljani, M.; Saray, R. Khoshbakhti; Bahlouli, K.

    2016-01-01

    In this work, a combined power cycle which includes a HCCI (Homogenous Charge Compression Ignition) engine and two ORCs (Organic Rankine Cycles) is introduced. In the proposed cycle, the waste heats from the engine cooling water and exhaust gases are utilized to drive the ORCs. A parametric study is conducted to show the effects of decision parameters on the performance and on the total cost rate of cycle. Results of the parametric study reveal that increasing the pinch point temperature difference of evaporator and temperature of the condenser leads to reduction in both exergy efficiency and total cost rate of the bottoming cycle. There is a specific evaporator temperature where exergy efficiency is improved, but the total cost rate of the bottoming cycle is maximized. Also, a multi-objective optimization strategy is performed to achieve the best system design parameters from both thermodynamic and economic aspects. The exergy efficiency and the total cost rate of the system have been considered as objective functions. Optimization results indicate that the exergy efficiency of the cycle increases from 44.96% for the base case to 46.02%. Also, approximately1.3% reduction in the cost criteria is achieved. Results of the multi-objective optimization justify the results obtained through the parametric study and demonstrate that the design parameters of both ORCs have conflict effect on the objective functions. - Highlights: • Two Organic Rankine bottoming cycles are coupled with an HCCI Engine. • Exergetic and Exergo-economic analysis of the bottoming cycle are reported. • The system is optimized using multi-objective genetic algorithm. • Objective functions are exergy efficiency and total cost rate of the system. • The exergy efficiency of the cycle increases from 44.96% to 46.02%.

  4. Cycles in deregulated electricity markets: Empirical evidence from two decades

    International Nuclear Information System (INIS)

    Arango, Santiago; Larsen, Erik

    2011-01-01

    In this article, we discuss the 'cycle hypothesis' in electricity generation, which states that the introduction of deregulation in an electricity system might lead to sustained fluctuations of over- and under-capacity. The occurrence of cycles is one of the major threats for electricity markets as it affects the security of supply, and creates uncertainty in both the profitability of electricity companies and in consumer prices. We discuss the background for these cycles using analogies with other capital-intensive industries, along with evidence from the analysis of behavioral simulation models as well as from experimental electricity markets. Using data from the oldest deregulated markets we find support for the hypothesis in the case of the English and Chilean markets, based on an autocorrelation analysis. Evidence from the Nordpool market is more ambiguous, although we might be observing the first half of a cycle in generation capacity. Comparing a simulation of the English market performed in 1992 with the actual performance we can observe that the qualitative behavior of the model is consistent with the actual evolution. Finally, we discuss possible mechanisms for damping cycles in electricity generation, such as mothballing, capacity payments, and reliability markets. - Research highlights: → We explore the emergence of cycles in the electricity generation capacity after deregulation. → We discuss the reason for cycles in generation capacity and compare different theories. → Analysis of England and Chile data show strong indications that cycles have emerged.

  5. Proliferation in cycle

    Energy Technology Data Exchange (ETDEWEB)

    Piao Yunsong [College of Physical Sciences, Graduate School of Chinese Academy of Sciences, Beijing 100049 (China)], E-mail: yspiao@gucas.ac.cn

    2009-06-15

    In the contracting phase with w{approx_equal}0, the scale invariant spectrum of curvature perturbation is given by the increasing mode of metric perturbation. In this Letter, it is found that if the contracting phase with w{approx_equal}0 is included in each cycle of a cycle universe, since the metric perturbation is amplified on super horizon scale cycle by cycle, after each cycle the universe will be inevitably separated into many parts independent of one another, each of which corresponds to a new universe and evolves up to next cycle, and then is separated again. In this sense, a cyclic multiverse scenario is actually presented, in which the universe proliferates cycle by cycle. We estimate the number of new universes proliferated in each cycle, and discuss the implications of this result.

  6. Proliferation in cycle

    International Nuclear Information System (INIS)

    Piao Yunsong

    2009-01-01

    In the contracting phase with w≅0, the scale invariant spectrum of curvature perturbation is given by the increasing mode of metric perturbation. In this Letter, it is found that if the contracting phase with w≅0 is included in each cycle of a cycle universe, since the metric perturbation is amplified on super horizon scale cycle by cycle, after each cycle the universe will be inevitably separated into many parts independent of one another, each of which corresponds to a new universe and evolves up to next cycle, and then is separated again. In this sense, a cyclic multiverse scenario is actually presented, in which the universe proliferates cycle by cycle. We estimate the number of new universes proliferated in each cycle, and discuss the implications of this result.

  7. DETECTING ALIEN LIMIT CYCLES NEAR A HAMILTONIAN 2-SADDLE CYCLE

    OpenAIRE

    LUCA, Stijn; DUMORTIER, Freddy; Caubergh, M.; Roussarie, R.

    2009-01-01

    This paper aims at providing and example of a cubic Hamiltonian 2-saddle cycle that after bifurcation can give rise to an alien limit cycle; this is a limit cycle that is not controlled by a zero of the related Abelian integral. To guarantee the existence of an alien limit cycle one can verify generic conditions on the Abelian integral and on the transition map associated to the connections of the 2-saddle cycle. In this paper, a general method is developed to compute the first and second der...

  8. A Two Dimensional Prediction of Solar Cycle 25

    Science.gov (United States)

    Munoz-Jaramillo, A.; Martens, P. C.

    2017-12-01

    To this date solar cycle most cycle predictions have focused on the forecast of solar cycle amplitude and cycle bell-curve shape. However, recent intriguing observational results suggest that all solar cycles follow the same longitudinal path regardless of their amplitude, and have a very similar decay once they reach a sufficient level of maturity. Cast in the light of our current understanding, these results suggest that the toroidal fields inside the Sun are subject to a very high turbulent diffusivity (of the order of magnitude of mixing-length estimates), and their equatorward propagation is driven by a steady meridional flow. Assuming this is the case, we will revisit the relationship between the polar fields at minimum and the amplitude of the next cycle and deliver a new generation of polar-field based predictions that include the depth of the minimum, as well as the latitude and time of the first active regions of solar cycle 25.

  9. Optimum gas turbine cycle for combined cycle power plant

    International Nuclear Information System (INIS)

    Polyzakis, A.L.; Koroneos, C.; Xydis, G.

    2008-01-01

    The gas turbine based power plant is characterized by its relatively low capital cost compared with the steam power plant. It has environmental advantages and short construction lead time. However, conventional industrial engines have lower efficiencies, especially at part load. One of the technologies adopted nowadays for efficiency improvement is the 'combined cycle'. The combined cycle technology is now well established and offers superior efficiency to any of the competing gas turbine based systems that are likely to be available in the medium term for large scale power generation applications. This paper has as objective the optimization of a combined cycle power plant describing and comparing four different gas turbine cycles: simple cycle, intercooled cycle, reheated cycle and intercooled and reheated cycle. The proposed combined cycle plant would produce 300 MW of power (200 MW from the gas turbine and 100 MW from the steam turbine). The results showed that the reheated gas turbine is the most desirable overall, mainly because of its high turbine exhaust gas temperature and resulting high thermal efficiency of the bottoming steam cycle. The optimal gas turbine (GT) cycle will lead to a more efficient combined cycle power plant (CCPP), and this will result in great savings. The initial approach adopted is to investigate independently the four theoretically possible configurations of the gas plant. On the basis of combining these with a single pressure Rankine cycle, the optimum gas scheme is found. Once the gas turbine is selected, the next step is to investigate the impact of the steam cycle design and parameters on the overall performance of the plant, in order to choose the combined cycle offering the best fit with the objectives of the work as depicted above. Each alterative cycle was studied, aiming to find the best option from the standpoint of overall efficiency, installation and operational costs, maintainability and reliability for a combined power

  10. Menstrual cycle pattern and fertility

    DEFF Research Database (Denmark)

    Kolstad, Henrik A.; Bonde, Jens Peter; Hjøllund, Niels Henrik

    1999-01-01

    OBJECTIVE: To characterize how the menstrual cycle pattern relates to fertility regardless of potential biases caused by inappropriate coital timing during the menstrual cycle or early embryonal loss. DESIGN: Prospective follow-up study. SETTING: Healthy couples recruited throughout Denmark....... PATIENT(S): Two hundred ninety-five couples who were planning their first pregnancy were followed up from the discontinuation of birth control until a pregnancy was recognized within six menstrual cycles. Early embryonal losses were detected by changes in urinary hCG levels. INTERVENTION(S): None. MAIN...... OUTCOME MEASURE(S): The probability of pregnancy occurring within one menstrual cycle (fecundity). RESULT(S): In women who had a cycle length that differed by >10 days from the usual cycle length, fecundity was approximately 25% that of women who had no variation (odds ratio 0.25, 95% confidence interval...

  11. Seasonal, Diurnal, and Solar-Cycle Variations of Electron Density at Two West Africa Equatorial Ionization Anomaly Stations

    Directory of Open Access Journals (Sweden)

    Frédéric Ouattara

    2012-01-01

    Full Text Available We analyse the variability of foF2 at two West Africa equatorial ionization anomaly stations (Ouagadougou and Dakar during three solar cycles (from cycle 20 to cycle 22, that is, from 1966 to 1998 for Ouagadougou and from 1971 to 1997 for Dakar. We examine the effect of the changing levels of solar extreme ultraviolet radiation with sunspot number. The study shows high correlation between foF2 and sunspot number (Rz. The correlation coefficient decreases from cycle 20 to cycle 21 at both stations. From cycle 21 to cycle 22 it decreases at Ouagadougou station and increases at Dakar station. The best correlation coefficient, 0.990, is obtained for Dakar station during solar cycle 22. The seasonal variation displays equinoctial peaks that are asymmetric between March and September. The percentage deviations of monthly average data from one solar cycle to another display variability with respect to solar cycle phase and show solar ultraviolet radiation variability with solar cycle phase. The diurnal variation shows a noon bite out with a predominant late-afternoon peak except during the maximum phase of the solar cycle. The diurnal Ouagadougou station foF2 data do not show a significant difference between the increasing and decreasing cycle phases, while Dakar station data do show it, particularly for cycle 21. The percentage deviations of diurnal variations from solar-minimum conditions show more ionosphere during solar cycle 21 at both stations for all three of the other phases of the solar cycle. There is no significant variability of ionosphere during increasing and decreasing solar cycle phases at Ouagadougou station, but at Dakar station there is a significant variability of ionosphere during these two solar-cycle phases.

  12. Analysis of X-ray induced cell-cycle perturbations in mouse osteosarcoma cells: a two-signal cell-cycle model

    International Nuclear Information System (INIS)

    Meeteren, A. van; Wijk, R. van; Stap, J.; Deys, B.F.

    1984-01-01

    The effects of X-irradiation on mouse osteosarcoma cells have been studied by time-lapse cinematography and the resulting pedigrees have been analysed statistically. It is shown that the irradiation treatment causes three types of cell kinetic lesions: cell death (disintegration), cell sterilization (failure to divide) and proliferation delay. The first two lesions are the most important with regard to survival of the irradiated cell in a clonal assay. Of these two lesions, sterilization appears to be highly correlated for sister cells, while this is not true for cell disintegration. This indicates that cell survival in a clonal assay may be a function of the ratio of the incidences of these two types of lesions. The X-ray-induced proliferation delay was studied in terms of intermitotic time distributions, mother-daughter correlation and sibling correlation in relation to the current cell-cycle phase at the time of treatment. This analysis shows that the effects of irradiation on these cell-cycle characteristics is highly cell-cycle-dependent. A qualitative model to account for the observations is presented. (author)

  13. Analysis of X-ray induced cell-cycle perturbations in mouse osteosarcoma cells: a two-signal cell-cycle model

    Energy Technology Data Exchange (ETDEWEB)

    Meeteren, A van; Wijk, R van [Rijksuniversiteit Utrecht (Netherlands); Stap, J; Deys, B F [Amsterdam Univ. (Netherlands)

    1984-03-01

    The effects of X-irradiation on mouse osteosarcoma cells have been studied by time-lapse cinematography and the resulting pedigrees have been analysed statistically. It is shown that the irradiation treatment causes three types of cell kinetic lesions: cell death (disintegration), cell sterilization (failure to divide) and proliferation delay. The first two lesions are the most important with regard to survival of the irradiated cell in a clonal assay. Of these two lesions, sterilization appears to be highly correlated for sister cells, while this is not true for cell disintegration. This indicates that cell survival in a clonal assay may be a function of the ratio of the incidences of these two types of lesions. The X-ray-induced proliferation delay was studied in terms of intermitotic time distributions, mother-daughter correlation and sibling correlation in relation to the current cell-cycle phase at the time of treatment. This analysis shows that the effects of irradiation on these cell-cycle characteristics is highly cell-cycle-dependent. A qualitative model to account for the observations is presented.

  14. Economic evaluation of fast reactor fuel cycling

    International Nuclear Information System (INIS)

    Hu Ping; Zhao Fuyu; Yan Zhou; Li Chong

    2012-01-01

    Economic calculation and analysis of two kinds of nuclear fuel cycle are conducted by check off method, based on the nuclear fuel cycling process and model for fast reactor power plant, and comparison is carried out for the economy of fast reactor fuel cycle and PWR once-through fuel cycle. Calculated based on the current price level, the economy of PWR one-through fuel cycle is better than that of the fast reactor fuel cycle. However, in the long term considering the rising of the natural uranium's price and the development of the post treatment technology for nuclear fuels, the cost of the fast reactor fuel cycle is expected to match or lower than that of the PWR once-through fuel cycle. (authors)

  15. Evaluation of two streamlined life cycle assessment methods

    International Nuclear Information System (INIS)

    Hochschomer, Elisabeth; Finnveden, Goeran; Johansson, Jessica

    2002-02-01

    Two different methods for streamlined life cycle assessment (LCA) are described: the MECO-method and SLCA. Both methods are tested on an already made case-study on cars fuelled with petrol or ethanol, and electric cars with electricity produced from hydro power or coal. The report also contains some background information on LCA and streamlined LCA, and a deschption of the case study used. The evaluation of the MECO and SLCA-methods are based on a comparison of the results from the case study as well as practical aspects. One conclusion is that the SLCA-method has some limitations. Among the limitations are that the whole life-cycle is not covered, it requires quite a lot of information and there is room for arbitrariness. It is not very flexible instead it difficult to develop further. We are therefore not recommending the SLCA-method. The MECO-method does in comparison show several attractive features. It is also interesting to note that the MECO-method produces information that is complementary compared to a more traditional quantitative LCA. We suggest that the MECO method needs some further development and adjustment to Swedish conditions

  16. Quasi-two-year cycle in indices of geomagnetic and solar activity

    International Nuclear Information System (INIS)

    Nuzhdina, M.A.

    1986-01-01

    The spectral, amplitude and phase analysis of monthly standardized anomalies in the indices of planetary geomagnetic disturbance and Wolf numbers for the 100-year period and 18-year time ranges are carried out. There is a weak correlation between the monthly anomalies of fluctuations of the Wolf numbers and planetary indices of geomagnetic distubance manifesting quasi-two-year cyclic recurrence. There is the quasi-two-year cycle of 26 months average duration in the indices of geomagnetic disturbance and Wolf numbers. The quasi-two-year cycle is a rather wide band with the oscillation periods of 21 to 29 months having different amplitudes and phases. The quasi-two-year cycle in geomagnetism and the Wolf numbers is unstable: for 100 years of observations its components change in amplitude and phase

  17. The Hamburg oceanic carbon cycle circulation model. Cycle 1

    International Nuclear Information System (INIS)

    Maier-Reimer, E.; Heinze, C.

    1992-02-01

    The carbon cycle model calculates the prognostic fields of oceanic geochemical carbon cycle tracers making use of a 'frozen' velocity field provided by a run of the LSG oceanic circulation model (see the corresponding manual, LSG=Large Scale Geostrophic). The carbon cycle model includes a crude approximation of interactions between sediment and bottom layer water. A simple (meridionally diffusive) one layer atmosphere model allows to calculate the CO 2 airborne fraction resulting from the oceanic biogeochemical interactions. (orig.)

  18. Wastes from selected activities in two light-water reactor fuel cycles

    International Nuclear Information System (INIS)

    Palmer, C.R.; Hill, O.F.

    1980-07-01

    This report presents projected volumes and radioactivities of wastes from the production of electrical energy using light-water reactors (LWR). The projections are based upon data developed for a recent environmental impact statement in which the transuranic wastes (i.e., those wastes containing certain long-lived alpha emitters at concentrations of at least 370 becquerels, or 10 nCi, per gram of waste) from fuel cycle activities were characterized. In addition, since the WG.7 assumed that all fuel cycle wastes except mill tailings are placed in a mined geologic repository, the nontransuranic wastes from several activities are included in the projections reported. The LWR fuel cycles considered are the LWR, once-through fuel cycle (Strategy 1), in which spent fuel is packaged in metal canisters and then isolated in geologic formations; and the LWR U/Pu recycle fuel cycle (Strategy 2), wherein spent fuel is reprocessed for recovery and recycle of uranium and plutonium in LWRs. The wastes projected for the two LWR fuel cycles are summarized. The reactor operations and decommissioning were found to dominate the rate of waste generation in each cycle. These activities account for at least 85% of the fuel cycle waste volume (not including head-end wastes) when normalized to per unit electrical energy generated. At 10 years out of reactor, however, spent fuel elements in Strategy 1 represent 98% of the fuel cycle activity but only 4% of the volume. Similarly, the packaged high-level waste, fuel hulls and hardware in Strategy 2 concentrate greater than 95% of the activity in 2% of the waste volume

  19. Fuel cycle cost uncertainty from nuclear fuel cycle comparison

    International Nuclear Information System (INIS)

    Li, J.; McNelis, D.; Yim, M.S.

    2013-01-01

    This paper examined the uncertainty in fuel cycle cost (FCC) calculation by considering both model and parameter uncertainty. Four different fuel cycle options were compared in the analysis including the once-through cycle (OT), the DUPIC cycle, the MOX cycle and a closed fuel cycle with fast reactors (FR). The model uncertainty was addressed by using three different FCC modeling approaches with and without the time value of money consideration. The relative ratios of FCC in comparison to OT did not change much by using different modeling approaches. This observation was consistent with the results of the sensitivity study for the discount rate. Two different sets of data with uncertainty range of unit costs were used to address the parameter uncertainty of the FCC calculation. The sensitivity study showed that the dominating contributor to the total variance of FCC is the uranium price. In general, the FCC of OT was found to be the lowest followed by FR, MOX, and DUPIC. But depending on the uranium price, the FR cycle was found to have lower FCC over OT. The reprocessing cost was also found to have a major impact on FCC

  20. On approximating restricted cycle covers

    NARCIS (Netherlands)

    Manthey, Bodo

    2008-01-01

    A cycle cover of a graph is a set of cycles such that every vertex is part of exactly one cycle. An $L$-cycle cover is a cycle cover in which the length of every cycle is in the set $L$. The weight of a cycle cover of an edge-weighted graph is the sum of the weights of its edges. We come close to

  1. FCC-hh turn-around cycle

    CERN Document Server

    Alemany Fernandez, Reyes; Bartmann, Wolfgang; Buffat, Xavier; Niemi, Arto; Schulte, Daniel; Solfaroli Camillocci, Matteo; Stoel, Linda

    2016-01-01

    The turn-around cycle time of a collider is defined as the time spent between the end of stable beams and the start of the next stable beams period, and its calculation is of fundamental importance. On one side it is a crucial ingredient for the computation of the optimal time spent in luminosity production, which defines the integrated luminosity per fill or store. On the other side, combined with the availability and reliability of the machine, it allows to perform a detailed breakdown of the operational performance of the collider over an operational season, i.e. percentage of time in stable beams and beam in the machine with respect to down time. This paper presents a preliminary operational cycle definition for the hadron-hadron Future Circular Collider, as a base line for estimating the corresponding turn-around time. The cycle definition is based on the Large Hadron Collider (LHC) operational cycle. Two turn-around times are presented, the theoretical one and a more realistic one based on the LHC exper...

  2. New one cycle criteria for optimizing preventive replacement policies

    International Nuclear Information System (INIS)

    Hamidi, Maryam; Szidarovszky, Ferenc; Szidarovszky, Miklos

    2016-01-01

    Models are introduced and examined for the optimum scheduling of preventive replacements. The “replace first” and “replace last” models are known from the literature if the long term expected cost per unit time is minimized. We will first introduce the one cycle counterparts of these models when the expected costs per unit time in a single cycle is minimized. If the unit performs identical projects sequentially then the “replace next” model assumes that the preventive replacement is postponed until the ongoing project is finished. The termination time of this project is random which also depends on the scheduled time of the preventive replacement in contrary to the “replace first” and “replace last” models. The mathematical models are formulated and conditions are given for the existence of finite optima. Numerical examples and a simulation study illustrate the methodology and the numerical results show interesting comparisons of the different models. - Highlights: • The Single cycle age replacement model is extended incorporating repairable failures. • In order to avoid project interruption costs, three model variants are discussed. • Model variants are replace first, replace last and replace next. • In many cases analytic solutions are derived and illustrated by numerical examples. • The different model variants and their results are compared based on simulation studies.

  3. Universality, marginal operators, and limit cycles

    International Nuclear Information System (INIS)

    Glazek, Stanislaw D.; Wilson, Kenneth G.

    2004-01-01

    The universality of renormalization-group limit-cycle behavior is illustrated with a simple discrete Hamiltonian model. A nonperturbative renormalization-group equation for the model is soluble analytically at criticality and exhibits one marginal operator (made necessary by the limit cycle) and an infinite set of irrelevant operators. Relevant operators are absent. The model exhibits an infinite series of bound-state energy eigenvalues. This infinite series approaches an exact geometric series as the eigenvalues approach zero--also a consequence of the limit cycle. Wegner's eigenvalues for irrelevant operators are calculated generically for all choices of parameters in the model. We show that Wegner's eigenvalues are independent of location on the limit cycle, in contrast with Wegner's operators themselves, which vary depending on their location on the limit cycle. An example is then used to illustrate numerically how one can tune the initial Hamiltonian to eliminate the first two irrelevant operators. After tuning, the Hamiltonian's bound-state eigenvalues converge much more quickly than otherwise to an exact geometric series

  4. Interventions to promote cycling: systematic review.

    Science.gov (United States)

    Yang, Lin; Sahlqvist, Shannon; McMinn, Alison; Griffin, Simon J; Ogilvie, David

    2010-10-18

    To determine what interventions are effective in promoting cycling, the size of the effects of interventions, and evidence of any associated benefits on overall physical activity or anthropometric measures. Systematic review. Published and unpublished reports in any language identified by searching 13 electronic databases, websites, reference lists, and existing systematic reviews, and papers identified by experts in the field. Review methods Controlled "before and after" experimental or observational studies of the effect of any type of intervention on cycling behaviour measured at either individual or population level. Twenty five studies (of which two were randomised controlled trials) from seven countries were included. Six studies examined interventions aimed specifically at promoting cycling, of which four (an intensive individual intervention in obese women, high quality improvements to a cycle route network, and two multifaceted cycle promotion initiatives at town or city level) were found to be associated with increases in cycling. Those studies that evaluated interventions at population level reported net increases of up to 3.4 percentage points in the population prevalence of cycling or the proportion of trips made by bicycle. Sixteen studies assessing individualised marketing of "environmentally friendly" modes of transport to interested households reported modest but consistent net effects equating to an average of eight additional cycling trips per person per year in the local population. Other interventions that targeted travel behaviour in general were not associated with a clear increase in cycling. Only two studies assessed effects of interventions on physical activity; one reported a positive shift in the population distribution of overall physical activity during the intervention. Community-wide promotional activities and improving infrastructure for cycling have the potential to increase cycling by modest amounts, but further controlled

  5. 'Benefits cycle' replacing premium cycle as consumerism takes hold.

    Science.gov (United States)

    2002-05-01

    The traditional premium cycle of ups and downs in rates is giving way to a new phenomenon--driven by the advent of consumerism in health care--termed the "benefits cycle" by one consultant. Rather than shifts in rates, he argues, the future will see shifts in benefits packages.

  6. Optimization of the fuel cycle

    International Nuclear Information System (INIS)

    Kidd, S.W.; Balu, K.; Boczar, P.G.; Krebs, W.D.

    1999-01-01

    The nuclear fuel cycle can be optimized subject to a wide range of criteria. Prime amongst these are economics, sustainability of resources, environmental aspects, and proliferation-resistance of the fuel cycle. Other specific national objectives will also be important. These criteria, and their relative importance, will vary from country to country, and with time. There is no single fuel cycle strategy that is optimal for all countries. Within the short term, the industry is attached to dominant thermal reactor technologies, which themselves have two main variants, a cycle closed by reprocessing of spent fuel and subsequent recycling and a once through one where spent fuel is stored in advance of geological disposal. However, even with current technologies, much can be done to optimize the fuel cycles to meet the relevant criteria. In the long term, resource sustainability can be assured for centuries through the use of fast breeder reactors, supporting high-conversion thermal reactors, possibly also utilizing the thorium cycle. These must, however, meet the other key criteria by being both economic and safe. (author)

  7. Performance of one and a half-effect absorption cooling cycle of H2O/LiBr system

    International Nuclear Information System (INIS)

    Wang Jianzhao; Zheng Danxing

    2009-01-01

    The performances of half-effect, single-effect and double-effect H 2 O/LiBr absorption cooling cycles were analyzed, and it was found that there is an obvious blank for generation temperature between the maximum generation temperature of the single-effect cycle and the minimum generation temperature of the double-effect cycle. It was proposed that the one and a half-effect (1.5-effect) cycle can fill up the blank perfectly. The state of the art in the 1.5-effect cycles was reviewed and analyzed, and two new configurations of 1.5-effect cycles were proposed. Three configurations of 1.5-effect cycles, which are suitable for H 2 O/LiBr as working fluids, were selected to be analyzed in detail. The 1.5-effect cycle shows the optimum performance at the foregoing blank of generation temperature. For example, under the conditions of evaporation temperature t E is 5 deg. C, and condensation temperature t C is 42 deg. C, and absorption temperature t A is 37 deg. C, the optimum range of generation temperature t G for the 1.5-effect cycle is from 110 deg. C to 140 deg. C. The coefficient of performance of the 1.5-effect cycle is about 1.0, which is more than 30% higher than that of the single-effect cycle at the same condition. The effects of the efficiency of solution heat exchanger, the generation temperature, the absorption temperature (or the condensation temperature) and the evaporation temperature on the performances of the three configurations of 1.5-effect cycle were analyzed. It was shown that the configuration II, which is composed with a high-temperature single-effect subcycle and a low-temperature half-effect subcycle, has the highest coefficient of performance and the best operational flexibility. Among the four parameters analyzed, the performances of 1.5-effect cycles are most sensitive to the change of absorption temperature (or condensation temperature), and then to the change of generation temperature.

  8. Comparative assessment of nuclear fuel cycles. Light-water reactor once-through, classical fast breeder reactor, and symbiotic fast breeder reactor cycles

    International Nuclear Information System (INIS)

    Hardie, R.W.; Barrett, R.J.; Freiwald, J.G.

    1980-06-01

    The object of the Alternative Nuclear Fuel Cycle Study is to perform comparative assessments of nuclear power systems. There are two important features of this study. First, this evaluation attempts to encompass the complete, integrated fuel cycle from mining of uranium ore to disposal of waste rather than isolated components. Second, it compares several aspects of each cycle - energy use, economics, technological status, proliferation, public safety, and commercial potential - instead of concentrating on one or two assessment areas. This report presents assessment results for three fuel cycles. These are the light-water reactor once-through cycle, the fast breeder reactor on the classical plutonium cycle, and the fast breeder reactor on a symbiotic cycle using plutonium and 233 U as fissile fuels. The report also contains a description of the methodology used in this assessment. Subsequent reports will present results for additional fuel cycles

  9. Heat exchanger inventory cost optimization for power cycles with one feedwater heater

    International Nuclear Information System (INIS)

    Qureshi, Bilal Ahmed; Antar, Mohamed A.; Zubair, Syed M.

    2014-01-01

    Highlights: • Cost optimization of heat exchanger inventory in power cycles is investigated. • Analysis for an endoreversible power cycle with an open feedwater heater is shown. • Different constraints on the power cycle are investigated. • The constant heat addition scenario resulted in the lowest value of the cost function. - Abstract: Cost optimization of heat exchanger inventory in power cycles with one open feedwater heater is undertaken. In this regard, thermoeconomic analysis for an endoreversible power cycle with an open feedwater heater is shown. The scenarios of constant heat rejection and addition rates, power as well as rate of heat transfer in the open feedwater heater are studied. All cost functions displayed minima with respect to the high-side absolute temperature ratio (θ 1 ). In this case, the effect of the Carnot temperature ratio (Φ 1 ), absolute temperature ratio (ξ) and the phase-change absolute temperature ratio for the feedwater heater (Φ 2 ) are qualitatively the same. Furthermore, the constant heat addition scenario resulted in the lowest value of the cost function. For variation of all cost functions, the smaller the value of the phase-change absolute temperature ratio for the feedwater heater (Φ 2 ), lower the cost at the minima. As feedwater heater to hot end unit cost ratio decreases, the minimum total conductance required increases

  10. Thermodynamic sensitivity analysis of a novel trigeneration thermodynamic cycle with two-phase expanders and two-phase compressors

    International Nuclear Information System (INIS)

    Briola, Stefano; Di Marco, Paolo; Gabbrielli, Roberto

    2017-01-01

    A novel Combined Cooling, Heating and Power (CCHP) cycle, operating with two-phase devices for the compression and expansion processes and a single-component wet working fluid, is proposed. A detailed sensitivity analysis of the novel CCHP cycle has been investigated in order to evaluate, in terms of energy performance indicators, its potentiality to serve typical trigenerative tertiary and industrial end-users with different fixed operating temperatures. In general, the novel CCHP cycle is characterized by higher energy performance indicators than a separated energy production system. The comparison between the novel CCHP cycle and several commercialized CCHP systems has been performed in the case studies related to tertiary and industrial end-users. The novel CCHP cycle shows a trigenerative capability in wide ranges of the end-users demands without surplus or deficit of the electric or thermal powers. Furthermore, the maximum allowable capital cost of the whole novel CCHP plant (BEPCC), that will assure the profitability of the investment, is calculated in the tertiary and industrial end-users case studies. For the tertiary end-user, the capital costs of the commercialized CCHP are between the minimum and maximum BEPCC values. On the contrary, for the industrial end-user, they are lower than the minimum and maximum BEPCC values. - Highlights: • Novel CCHP cycle with two-phase expanders and compressors has been conceived. • Novel CCHP cycle has higher performances than a separated energy production system. • Novel CCHP cycle satisfies the user demands in wide ranges without surplus/deficit. • Tertiary user: novel CCHP cycle is competitive against marketed CCHP systems. • Industrial user: novel CCHP cycle is not competitive against marketed CCHP systems.

  11. International Business Cycle

    Directory of Open Access Journals (Sweden)

    Marek Lubiński

    2007-04-01

    Full Text Available Prime stylized facts of international business cycle theory refer to positive correlation in the cyclical components of important macroeconomic variables across countries. However a number of indicators of business cycle synchronization do not point to clear trends. It can be ascribed to the fact that different forces influence level of business cycle correlation. When investigating into the forces behind the commonness in aggregate fluctuations economic research seems to have pointed in two directions. One strand of the literature examines the idea of common exogenous shocks that affect economies simultaneously. In addition to that economic interdependencies such as trade in goods and services or capital account transactions may serve as the channels through which disturbances spill over across countries.The observed degree of output co movement reflects both the nature of the shocks that have occurred and the degree of economic interdependence. In the periods when common shocks prevail level of synchronization is usually higher than in times of transmission dominance.

  12. Thermodynamic Analysis of Supplementary-Fired Gas Turbine Cycles

    DEFF Research Database (Denmark)

    Elmegaard, Brian; Henriksen, Ulrik Birk; Qvale, Einar Bjørn

    2003-01-01

    to result in a high marginal efficiency. The paper shows that depending on the application, this is not always the case. The interest in this cycle arises from a recent demonstration of the feasibility of a two-stage gasification process through construction of several plants. The gas from this process...... could be divided into two streams, one for primary and one for supplementary firing. A preliminary analysis of the ideal, recuperated Brayton cycle shows that for this cycle any supplementary firing will have a marginal efficiency of unity per extra unit of fuel. The same result is obtained...

  13. Air bottoming cycle, an alternative to combined cycles. Final report

    Energy Technology Data Exchange (ETDEWEB)

    Kaikko, J. [Royal Inst. of Techn., Stockholm (Sweden). Dept. of Energy Technology

    2001-10-01

    In this work, the idea of Air Bottoming Cycle (ABC) has been studied. The objectives for the work have been to establish an understanding of the concept for power and heat generation as well as to find - if possible - feasible concepts for future use in the Swedish energy system. Combined cycle in power generation is an established technology. In the conventional combined cycle, a gas turbine works as a topping cycle together with the steam (Rankine) bottoming cycle. In the ABC the steam bottoming cycle is replaced with a gas turbine (Brayton) bottoming cycle having air as a working fluid. The two gas turbines are thermally connected over a gas-to-gas heat exchanger. This concept promises savings in weight and cost, as well as operating benefits, compared to the Rankine bottoming technology. The ABC has been modelled using a heat balance program, and a parametric study for the concept optimisation as well as for off-design analysis has been performed. Performance of the ABC has been compared to other, established technologies. A preliminary economic evaluation has been made. As a result of the study, it is clarified that the Rankine bottoming cycle with steam remains superior to the ABC as regards electrical efficiency in the medium and large power scale. For small-scale applications (<10 MW{sub e}) where the thermodynamic advantage of the Rankine cycle is not dominating any longer and its economy is burdened by the heavy investment structure, the ABC becomes the better alternative for energy utilisation. A preliminary economic evaluation shows that (at energy prices autumn 2000) the ABC is at the same level as the comparable small-scale cogeneration installations. Due to high power-to-heat ratio however, higher electricity prices will favour the ABC. One interesting feature of the ABC is that about 50% of the dissipated low-value heat from the cycle is carried by clean (sterile) air at the temperature around 200 deg C. This air can be utilised for space heating or

  14. Fuel cycle modelling of open cycle thorium-fuelled nuclear energy systems

    International Nuclear Information System (INIS)

    Ashley, S.F.; Lindley, B.A.; Parks, G.T.; Nuttall, W.J.; Gregg, R.; Hesketh, K.W.; Kannan, U.; Krishnani, P.D.; Singh, B.; Thakur, A.; Cowper, M.; Talamo, A.

    2014-01-01

    Highlights: • We study three open cycle Th–U-fuelled nuclear energy systems. • Comparison of these systems is made to a reference U-fuelled EPR. • Fuel cycle modelling is performed with UK NNL code “ORION”. • U-fuelled system is economically favourable and needs least separative work per kWh. • Th–U-fuelled systems offer negligible waste and proliferation resistance advantages. - Abstract: In this study, we have sought to determine the advantages, disadvantages, and viability of open cycle thorium–uranium-fuelled (Th–U-fuelled) nuclear energy systems. This has been done by assessing three such systems, each of which requires uranium enriched to ∼20% 235 U, in comparison to a reference uranium-fuelled (U-fuelled) system over various performance indicators, spanning material flows, waste composition, economics, and proliferation resistance. The values of these indicators were determined using the UK National Nuclear Laboratory’s fuel cycle modelling code ORION. This code required the results of lattice-physics calculations to model the neutronics of each nuclear energy system, and these were obtained using various nuclear reactor physics codes and burn-up routines. In summary, all three Th–U-fuelled nuclear energy systems required more separative work capacity than the equivalent benchmark U-fuelled system, with larger levelised fuel cycle costs and larger levelised cost of electricity. Although a reduction of ∼6% in the required uranium ore per kWh was seen for one of the Th–U-fuelled systems compared to the reference U-fuelled system, the other two Th–U-fuelled systems required more uranium ore per kWh than the reference. Negligible advantages and disadvantages were observed for the amount and the properties of the spent nuclear fuel (SNF) generated by the systems considered. Two of the Th–U-fuelled systems showed some benefit in terms of proliferation resistance of the SNF generated. Overall, it appears that there is little

  15. SYNBURN: fast-reactor fuel-cycle program

    International Nuclear Information System (INIS)

    Pizzica, P.A.; Meneley, D.A.

    1976-01-01

    The SYNBURN computer program for fast reactors will calculate all the neutronics necessary to completely characterize the equilibrium cycle as well as the startup to equilibrium cycles. The program's run time is very short and this makes the program suitable for survey of parametric studies. It can search on the cycle time for a specified burnup, for the shim control necessary for criticality as well as feed enrichments and the enrichment ratio among core zones. SYNBURN synthesizes in a very simple fashion the one-dimensional fluxes in radial and axial geometry to achieve an approximate two-dimensional solution which agrees very well with the exact two-dimensional solution when measuring regional integrated quantities

  16. Fuel cycle oriented approach

    International Nuclear Information System (INIS)

    Petit, A.

    1987-01-01

    The term fuel cycle oriented approach is currently used to designate two quite different things: the attempt to consider all or part of a national fuel cycle as one material balance area (MBA) or to consider individual MBAs existing in a state while designing a unique safeguards approach for each and applying the principle of nondiscrimination to fuel cycles as a whole, rather than to individual facilities. The merits of such an approach are acceptability by the industry and comparison with the contemplated establishment of long-term criteria. The following points concern the acceptability by the industry: (1) The main interest of the industry is to keep an open international market and therefore, to have effective and efficient safeguards. (2) The main concerns of the industry regarding international safeguards are economic burden, intrusiveness, and discrimination. Answers to these legitimate concerns, which retain the benefits of a fuel cycle oriented approach, are needed. More specifically, the problem of reimbursing the operator the costs that he has incurred for the safeguards must be considered

  17. Quantitative Cell Cycle Analysis Based on an Endogenous All-in-One Reporter for Cell Tracking and Classification

    Directory of Open Access Journals (Sweden)

    Thomas Zerjatke

    2017-05-01

    Full Text Available Cell cycle kinetics are crucial to cell fate decisions. Although live imaging has provided extensive insights into this relationship at the single-cell level, the limited number of fluorescent markers that can be used in a single experiment has hindered efforts to link the dynamics of individual proteins responsible for decision making directly to cell cycle progression. Here, we present fluorescently tagged endogenous proliferating cell nuclear antigen (PCNA as an all-in-one cell cycle reporter that allows simultaneous analysis of cell cycle progression, including the transition into quiescence, and the dynamics of individual fate determinants. We also provide an image analysis pipeline for automated segmentation, tracking, and classification of all cell cycle phases. Combining the all-in-one reporter with labeled endogenous cyclin D1 and p21 as prime examples of cell-cycle-regulated fate determinants, we show how cell cycle and quantitative protein dynamics can be simultaneously extracted to gain insights into G1 phase regulation and responses to perturbations.

  18. A non-conventional interpretation of thermal regeneration in steam cycles

    International Nuclear Information System (INIS)

    Bracco, Stefano; Damiani, Lorenzo

    2012-01-01

    Highlights: ► A better understanding of the concept of thermal regeneration in steam cycles. ► Use of a system composed by a non-regenerative cycle and several reverse cycles. ► Calculation of the heat pumps coefficients of performance. ► New interesting formulations of the regenerative cycle efficiency. -- Abstract: The paper aims to contribute to a better understanding of the thermodynamic concept of heat regeneration in steam power plants with a finite number of bleedings. A regenerative Rankine cycle is compared to a complex system (CHC – complete hybrid cycle) composed by one non-regenerative Rankine cycle (HEC – hybrid engine cycle) and more reverse cycles (RCs – reverse cycles), as many as the number of the bleedings, able to pump heat from the condenser to a series of surface feedwater heaters, disposed upstream of the steam plant boiler. The COPs (coefficients of performance) of the heat pumps are evaluated, and new interesting formulations of the efficiency of the regenerative steam cycle are proposed. In particular a steam cycle with two bleedings is analyzed, neglecting heat losses and pressure drops in the boiler and considering irreversibility only along the expansion line of the steam turbine and into the feedwater heaters. The efficiency and the work of the regenerative cycle are compared to the analogous values of the CHC cycle composed by one simple steam cycle (HEC) and two heat pump cycles (RCs), with steam as the working fluid. The two reverse cycles are considered completely reversible and raising heat from the condenser temperature to the bled steam condensing temperature. The paper shows the most significant results of the study in order to analyze the regenerative cycle and the CHC cycle in comparison with the non-regenerative Rankine cycle; in particular, the analysis is focused on the evaluation of the useful work, the heat supplied and the heat rejected for the examined cycles.

  19. International Business Cycle

    OpenAIRE

    Marek Lubiński

    2007-01-01

    Prime stylized facts of international business cycle theory refer to positive correlation in the cyclical components of important macroeconomic variables across countries. However a number of indicators of business cycle synchronization do not point to clear trends. It can be ascribed to the fact that different forces influence level of business cycle correlation. When investigating into the forces behind the commonness in aggregate fluctuations economic research seems to have pointed in two ...

  20. Exergetic comparison of two different cooling technologies for the power cycle of a thermal power plant

    International Nuclear Information System (INIS)

    Blanco-Marigorta, Ana M.; Victoria Sanchez-Henriquez, M.; Pena-Quintana, Juan A.

    2011-01-01

    Exergetic analysis is without any doubt a powerful tool for developing, evaluating and improving an energy conversion system. In the present paper, two different cooling technologies for the power cycle of a 50 MWe solar thermal power plant are compared from the exergetic viewpoint. The Rankine cycle design is a conventional, single reheat design with five closed and one open extraction feedwater heaters. The software package GateCycle is used for the thermodynamic simulation of the Rankine cycle model. The first design configuration uses a cooling tower while the second configuration uses an air cooled condenser. With this exergy analysis we identify the location, magnitude and the sources or thermodynamic inefficiencies in this thermal system. This information is very useful for improving the overall efficiency of the power system and for comparing the performance of both technologies.

  1. CANFLEX-RU fuel development programs as one option of advanced fuel cycles in Korea

    International Nuclear Information System (INIS)

    Suk, Ho Chun; Sim, Ki-Seob; Chung, Jang Hwan

    1999-01-01

    As one of the possible fuel cycles in Korea, RU (Recycled Uranium) fuel offers a very attractive alternative to the use of NU (Natural Uranium) and SEU in the CANDU reactors, because Korea is a unique country having both PWR and CANDU reactors. Korea can therefore exploit the natural synergism between the two reactor types to minimise overall waste production, and maximise energy derived from the fuel, by burning the spent fuel from its PWR reactors in CANDU reactors. Potential benefits can be derived from a number of stages in the fuel cycle: no enrichment required, no enrichment tails, direct conversion to UO 2 lower sensitivity to 234 U and 236 U absorption in the CANDU reactor, expected lower cost relative to NU and SEU. These benefits all fit well with the PWR-CANDU fuel cycle synergy. RU arising from the reprocessing of European and Japanese oxide spent fuel by 2000 is projected to be approaching 25,000 te. The use of RU fuel in a CANDU-6 reactor should result in no serious radiological difficulties and no requirements for special precautions and should not require any new technologies for the fuel fabrication and handling. A KAERI's feasibility shows that the use of the CANFLEX bundle as the carrier for RU will be compatible with the reactor design, current safety and operational requirements, and there will be no significant fuel performance difference from the CANDU 37-element NU fuel bundle. Compared with the 37-element NU bundle, the RU fuel has significantly improved fuel cycle economics derived from increased burnups, a large reduction in fuel requirements and spent fuel arisings and the potential lower cost for RU material. There is the potential for annual fuel cost savings to be in the range of one-third to two-thirds, with enhanced operating margins using RU in the CANFLEX bundle design. These benefits provide the rationale for justifying R and D effort on the use of RU fuel for advanced fuel cycles in the CANDU reactors of Korea. The RU fuel

  2. Reproductive cycles in tropical intertidal gastropods are timed around tidal amplitude cycles.

    Science.gov (United States)

    Collin, Rachel; Kerr, Kecia; Contolini, Gina; Ochoa, Isis

    2017-08-01

    Reproduction in iteroparous marine organisms is often timed with abiotic cycles and may follow lunar, tidal amplitude, or daily cycles. Among intertidal marine invertebrates, decapods are well known to time larval release to coincide with large amplitude nighttime tides, which minimizes the risk of predation. Such bimonthly cycles have been reported for few other intertidal invertebrates. We documented the reproduction of 6 gastropod species from Panama to determine whether they demonstrate reproductive cycles, whether these cycles follow a 2-week cycle, and whether cycles are timed so that larval release occurs during large amplitude tides. Two of the species ( Crepidula cf. marginalis and Nerita scabricosta ) showed nonuniform reproduction, but without clear peaks in timing relative to tidal or lunar cycles. The other 4 species show clear peaks in reproduction occurring every 2 weeks. In 3 of these species ( Cerithideopsis carlifornica var. valida, Littoraria variegata , and Natica chemnitzi ), hatching occurred within 4 days of the maximum amplitude tides. Siphonaria palmata exhibit strong cycles, but reproduction occurred during the neap tides. Strong differences in the intensity of reproduction of Cerithideopsis carlifornica , and in particular, Littoraria variegata , between the larger and smaller spring tides of a lunar month indicate that these species time reproduction with the tidal amplitude cycle rather than the lunar cycle. For those species that reproduce during both the wet and dry seasons, we found that reproductive timing did not differ between seasons despite strong differences in temperature and precipitation. Overall, we found that most (4/6) species have strong reproductive cycles synchronized with the tidal amplitude cycle and that seasonal differences in abiotic factors do not alter these cycles.

  3. Human chorionic gonadotropin-administered natural cycle versus spontaneous ovulatory cycle in patients undergoing two pronuclear zygote frozen-thawed embryo transfer.

    Science.gov (United States)

    Lee, You-Jung; Kim, Chung-Hoon; Kim, Do-Young; Ahn, Jun-Woo; Kim, Sung-Hoon; Chae, Hee-Dong; Kang, Byung-Moon

    2018-03-01

    To compare human chorionic gonadotropin (HCG)-administered natural cycle with spontaneous ovulatory cycle in patients undergoing frozen-thawed embryo transfer (FTET) in natural cycles. In this retrospective cohort study, we analyzed the clinical outcome of a total of 166 consecutive FTET cycles that were performed in either natural cycle controlled by HCG for ovulation triggering (HCG group, n=110) or natural cycle with spontaneous ovulation (control group, n=56) in 166 infertile patients between January 2009 and November 2013. There were no differences in patients' characteristics between the 2 groups. The numbers of oocytes retrieved, mature oocytes, fertilized oocytes, grade I or II embryos and frozen embryos in the previous in vitro fertilization (IVF) cycle in which embryos were frozen were comparable between the HCG and control groups. Significant differences were not also observed between the 2 groups in clinical pregnancy rate (CPR), embryo implantation rate, miscarriage rate, live birth rate and multiple CPR. However, the number of hospital visits for follicular monitoring was significantly fewer in the HCG group than in the control group ( P cycle reduces the number of hospital visits for follicular monitoring without any detrimental effect on FTET outcome when compared with spontaneous ovulatory cycles in infertile patients undergoing FTET in natural ovulatory cycles.

  4. Thermodynamics analysis of a modified dual-evaporator CO2 transcritical refrigeration cycle with two-stage ejector

    International Nuclear Information System (INIS)

    Bai, Tao; Yan, Gang; Yu, Jianlin

    2015-01-01

    In this paper, a modified dual-evaporator CO 2 transcritical refrigeration cycle with two-stage ejector (MDRC) is proposed. In MDRC, the two-stage ejector are employed to recover the expansion work from cycle throttling processes and enhance the system performance and obtain dual-temperature refrigeration simultaneously. The effects of some key parameters on the thermodynamic performance of the modified cycle are theoretically investigated based on energetic and exergetic analyses. The simulation results for the modified cycle show that two-stage ejector exhibits more effective system performance improvement than the single ejector in CO 2 dual-temperature refrigeration cycle, and the improvements of the maximum system COP (coefficient of performance) and system exergy efficiency could reach 37.61% and 31.9% over those of the conventional dual-evaporator cycle under the given operating conditions. The exergetic analysis for each component at optimum discharge pressure indicates that the gas cooler, compressor, two-stage ejector and expansion valves contribute main portion to the total system exergy destruction, and the exergy destruction caused by the two-stage ejector could amount to 16.91% of the exergy input. The performance characteristics of the proposed cycle show its promise in dual-evaporator refrigeration system. - Highlights: • Two-stage ejector is used in dual-evaporator CO 2 transcritical refrigeration cycle. • Energetic and exergetic methods are carried out to analyze the system performance. • The modified cycle could obtain dual-temperature refrigeration simultaneously. • Two-stage ejector could effectively improve system COP and exergy efficiency

  5. The remote ischemic preconditioning algorithm: effect of number of cycles, cycle duration and effector organ mass on efficacy of protection.

    Science.gov (United States)

    Johnsen, Jacob; Pryds, Kasper; Salman, Rasha; Løfgren, Bo; Kristiansen, Steen Buus; Bøtker, Hans Erik

    2016-03-01

    Remote ischemic preconditioning (rIPC), induced by cycles of transient limb ischemia and reperfusion (IR), is cardioprotective. The optimal rIPC-algorithm is not established. We investigated the effect of cycle numbers and ischemia duration within each rIPC-cycle and the influence of effector organ mass on the efficacy of cardioprotection. Furthermore, the duration of the early phase of protection by rIPC was investigated. Using a tourniquet tightened at the inguinal level, we subjected C57Bl/6NTac mice to intermittent hind-limb ischemia and reperfusion. The rIPC-protocols consisted of (I) two, four, six or eight cycles, (II) 2, 5 or 10 min of ischemia in each cycle, (III) single or two hind-limb occlusions and (IV) 0.5, 1.5, 2.0 or 2.5 h intervals from rIPC to index cardiac ischemia. All rIPC algorithms were followed by 5 min of reperfusion. The hearts were subsequently exposed to 25 min of global ischemia and 60 min of reperfusion in an ex vivo Langendorff model. Cardioprotection was evaluated by infarct size and post-ischemic hemodynamic recovery. Four to six rIPC cycles yielded significant cardioprotection with no further protection by eight cycles. Ischemic cycles lasting 2 min offered the same protection as cycles of 5 min ischemia, whereas prolonged cycles lasting 10 min abrogated protection. One and two hind-limb preconditioning were equally protective. In our mouse model, the duration of protection by rIPC was 1.5 h. These findings indicate that the number and duration of cycles rather than the tissue mass exposed to rIPC determines the efficacy of rIPC.

  6. On acyclicity of games with cycles

    DEFF Research Database (Denmark)

    Andersson, Klas Olof Daniel; Hansen, Thomas Dueholm; Gurvich, Vladimir

    2010-01-01

    We study restricted improvement cycles (ri-cycles) in finite positional n-person games with perfect information modeled by directed graphs (di-graphs) that may contain directed cycles (di-cycles). We assume that all these di-cycles form one outcome c, for example, a draw. We obtain criteria...

  7. One physical educator's career cycle: strong start, great run, approaching finish.

    Science.gov (United States)

    Woods, Amelia Mays; Lynn, Susan K

    2014-03-01

    This article is nested within a longitudinal project examining 6 teachers' journeys along their career cycles (Lynn & Woods, 2010; Woods & Earls, 1995; Woods & Lynn, 2001). Two participants from the initial 6 continue to teach K-12 physical education; 1 of these participants, Everett, is examined in the current study. This veteran teacher's career-cycle movement and the environmental factors that both enhanced and constrained his career development are examined through the lens of Fessler and Christensen's career cycle model (1992). Data sources included: 8 formal interviews with Everett; formal interviews with his university teacher educators, student-teacher supervisor, principal, and spouse; informal interviews; field notes; and systematic teaching observations. An interpretative framework was used to assess the perceptions and meanings Everett gave to experiences as a physical educator and coach. Several factors acutely influenced Everett's career progression, including: (a) his individual disposition, (b) the impact and continued influence of a professional preparation program, and (c) his school and community support. He entered the profession with great promise and spent most of his career in the enthusiastic and growing, and the career stability, stages before shifting into the career frustration stage where he currently remains. Everett was able to negotiate personal and organizational environmental factors that have been identified as barriers for some physical educators. Therefore, viewing his professional life through the lens of the career cycle provides insights into the areas of change necessary to motivate and retain high-quality physical educators such as Everett.

  8. Air bottoming cycle, an alternative to combined cycles. Final report

    Energy Technology Data Exchange (ETDEWEB)

    Kaikko, J. [Royal Inst. of Tech., Stockholm (Sweden). Dept. of Energy Technology

    2002-02-01

    In this work, the idea of Air Bottoming Cycle (ABC) has been studied. The objectives for the work have been to establish an understanding of the concept for power and heat generation as well as to find - if possible - feasible concepts for future use in the Swedish energy system. Combined cycle in power generation is an established technology. In the conventional combined cycle, a gas turbine works as a topping cycle together with the steam (Rankine) bottoming cycle. In the ABC the steam bottoming cycle is replaced with a gas turbine (Brayton) bottoming cycle having air as a working fluid. The two gas turbines are thermally connected over a gas-to-gas heat exchanger. This concept promises savings in weight and cost, as well as operating benefits, compared to the Rankine bottoming technology. The ABC has been modelled using a heat balance program, and a parametric study for the concept optimisation as well as for off-design analysis has been performed. Performance of the ABC has been compared to other, established technologies. A preliminary economic evaluation has been made. As a result of the study, it is clarified that the Rankine bottoming cycle with steam remains superior to the ABC as regards electrical efficiency in the medium and large power scale. For small-scale applications (<10 MW{sub e}) where the thermodynamic advantage of the Rankine cycle is not dominating any longer and its economy is burdened by the heavy investment structure, the ABC becomes the better alternative for energy utilisation. A preliminary economic evaluation shows that (at energy prices autumn 2000) the ABC is at the same level as the comparable small-scale cogeneration installations. Due to high power-to-heat ratio however, higher electricity prices will favour the ABC. One interesting feature of the ABC is that about 50% of the dissipated low-value heat from the cycle is carried by clean (sterile) air at the temperature around 200 deg C. This air can be utilised for space heating or

  9. The Life Cycle of Centrioles

    OpenAIRE

    Hatch, E.; Stearns, T.

    2010-01-01

    Centrioles organize the centrosome and nucleate the ciliary axoneme, and the centriole life cycle has many parallels to the chromosome cycle. The centriole cycle in animals begins at fertilization with the contribution of two centrioles by the male gamete. In the ensuing cell cycles, the duplication of centrioles is controlled temporally, spatially, and numerically. As a consequence of the duplication mechanism, the two centrioles in a typical interphase cell are of different ages and have di...

  10. Cycle to Cycle Variation Study in a Dual Fuel Operated Engine

    KAUST Repository

    Pasunurthi, Shyamsundar

    2017-03-28

    The standard capability of engine experimental studies is that ensemble averaged quantities like in-cylinder pressure from multiple cycles and emissions are reported and the cycle to cycle variation (CCV) of indicated mean effective pressure (IMEP) is captured from many consecutive combustion cycles for each test condition. However, obtaining 3D spatial distribution of all the relevant quantities such as fuel-air mixing, temperature, turbulence levels and emissions from such experiments is a challenging task. Computational Fluid Dynamics (CFD) simulations of engine flow and combustion can be used effectively to visualize such 3D spatial distributions. A dual fuel engine is considered in the current study, with manifold injected natural gas (NG) and direct injected diesel pilot for ignition. Multiple engine cycles in 3D are simulated in series like in the experiments to investigate the potential of high fidelity RANS simulations coupled with detailed chemistry, to accurately predict the CCV. Cycle to cycle variation (CCV) is expected to be due to variabilities in operating and boundary conditions, in-cylinder stratification of diesel and natural gas fuels, variation in in-cylinder turbulence levels and velocity flow-fields. In a previous publication by the authors [1], variabilities in operating and boundary conditions are incorporated into several closed cycle simulations performed in parallel. Stochastic variations/stratifications of fuel-air mixture, turbulence levels, temperature and internal combustion residuals cannot be considered in such closed cycle simulations. In this study, open cycle simulations with port injection of natural gas predicted the combined effect of the stratifications on the CCV of in-cylinder pressure. The predicted Coefficient of Variation (COV) of cylinder pressure is improved compared to the one captured by closed cycle simulations in parallel.

  11. THE BIMODAL STRUCTURE OF THE SOLAR CYCLE

    Energy Technology Data Exchange (ETDEWEB)

    Du, Z. L., E-mail: zldu@nao.cas.cn [Key Laboratory of Solar Activity, National Astronomical Observatories, Chinese Academy of Sciences, Beijing 100012 (China)

    2015-05-01

    Some properties of the 11 yr solar cycle can be explained by the current solar dynamo models. However, some other features remain not well understood such as the asymmetry of the cycle, the double-peaked structure, and the “Waldmeier effect” that a stronger cycle tends to have less rise time and a shorter cycle length. We speculate that the solar cycle is governed by a bi-dynamo model forming two stochastic processes depicted by a bimodal Gaussian function with a time gap of about 2 yr, from which the above features can be reasonably explained. The first one describes the main properties of the cycle dominated by the current solar dynamo models, and the second one occurs either in the rising phase as a short weak explosive perturbation or in the declining phase as a long stochastic perturbation. The above function is the best one selected from several in terms of the Akaike information criterion. Through analyzing different distributions, one might speculate about the dominant physical process inside the convection zone. The secondary (main) process is found to be closely associated with complicated (simple) active ranges. In effect, the bi-dynamo model is a reduced form of a multi-dynamo model, which could occur from the base of the convection zone through its envelope and from low to high heliographic latitude, reflecting the active belts in the convection zone. These results are insensitive to the hemispheric asymmetry, smoothing filters, and distribution functions selected and are expected to be helpful in understanding the formation of solar and stellar cycles.

  12. Future fuel cycles

    International Nuclear Information System (INIS)

    Archinoff, G.H.

    1980-01-01

    A fuel cycle must offer both financial and resource savings if it is to be considered for introduction into Ontario's nuclear system. The most promising alternative CANDU fuel cycles are examined in the context of both of these factors over a wide range of installed capacity growth rates and economic assumptions, in order to determine which fuel cycle, or cycles, should be introduced, and when. It is concluded that the optimum path for the long term begins with the prompt introduction of the low-enriched-uranium fuel cycle. For a wide range of conditions, this cycle remains the optimum throughout the very long term. Conditions of rapid nuclear growth and very high uranium price escalation rates warrant the supersedure of the low-enriched-uranium cycle by either a plutonium-topped thorium cycle or plutonium recycle, beginning between 2010 and 2025. It is also found that the uranium resource position is sound in terms of both known resources and production capability. Moreover, introduction of the low-enriched-uranium fuel cycle and 1250 MWe reactor units will assure the economic viability of nuclear power until at least 2020, even if uranium prices increase at a rate of 3.5% above inflation. The interrelationship between these two conclusions lies in the tremendous incentive for exploration which will occur if the real uranium price escalation rate is high. From a competitive viewpoint, nuclear power can withstand increases in the price of uranium. However, such increases will likely further expand the resource base, making nuclear an even more reliable energy source. (auth)

  13. Power conversion systems based on Brayton cycles for fusion reactors

    International Nuclear Information System (INIS)

    Linares, J.I.; Herranz, L.E.; Moratilla, B.Y.; Serrano, I.P.

    2011-01-01

    This paper investigates Brayton power cycles for fusion reactors. Two working fluids have been explored: helium in classical configurations and CO 2 in recompression layouts (Feher cycle). Typical recuperator arrangements in both cycles have been strongly constrained by low temperature of some of the energy thermal sources from the reactor. This limitation has been overcome in two ways: with a combined architecture and with dual cycles. Combined architecture couples the Brayton cycle with a Rankine one capable of taking advantage of the thermal energy content of the working fluid after exiting the turbine stage (iso-butane and steam fitted best the conditions of the He and CO 2 cycles, respectively). Dual cycles set a specific Rankine cycle to exploit the lowest quality thermal energy source, allowing usual recuperator arrangements in the Brayton cycle. The results of the analyses indicate that dual cycles could reach thermal efficiencies around 42.8% when using helium, whereas thermal performance might be even better (46.7%), if a combined CO 2 -H 2 O cycle was set.

  14. Hybrid Combined Cycles with Biomass and Waste Fired Bottoming Cycle - a Literature Study

    Energy Technology Data Exchange (ETDEWEB)

    Petrov, Miroslav P.

    2002-02-01

    Biomass is one of the main natural resources in Sweden. The present low-CO{sub 2} emission characteristics of the Swedish electricity production system (hydro and nuclear) can be retained only by expansion of biofuel applications for energy purposes. Domestic Swedish biomass resources are vast and renewable, but not infinite. They must be utilized as efficiently as possible, in order to make sure that they meet the conditions for sustainability in the future. Application of efficient power generation cycles at low costs is essential for meeting this challenge. This applies also to municipal solid waste incineration with energy extraction, which should be preferred to its dumping in landfills. Hybrid dual-fuel combined cycle units are a simple and affordable way to increase the electric efficiency of biofuel energy utilization, without big investments, uncertainties or loss of reliability arising from complicated technologies. Configurations of such power cycles are very flexible and reliable. Their potential for high electric efficiency in condensing mode, high total efficiency in combined heat and power mode and unrivalled load flexibility is explored in this project. The present report is a literature study that concentrates on certain biomass utilization technologies, in particular the design and performance of hybrid combined cycle power units of various configurations, with gas turbines and internal combustion engines as topping cycles. An overview of published literature and general development trends on the relevant topic is presented. The study is extended to encompass a short overview of biomass utilization as an energy source (focusing on Sweden), history of combined cycles development with reference especially to combined cycles with supplementary firing and coal-fired hybrid combined cycles, repowering of old steam units into hybrid ones and combined cycles for internal combustion engines. The hybrid combined cycle concept for municipal solid waste

  15. Fuel cycle management

    International Nuclear Information System (INIS)

    Herbin, H.C.

    1977-01-01

    The fuel cycle management is more and more dependent on the management of the generation means among the power plants tied to the grid. This is due mainly because of the importance taken by the nuclear power plants within the power system. The main task of the fuel cycle management is to define the refuelling pattern of the new and irradiated fuel assemblies to load in the core as a function of: 1) the differences which exist between the actual conditions of the core and what was expected for the present cycle, 2) the operating constraints and the reactor availability, 3) the technical requirements in safety and the technological limits of the fuel, 4) the economics. Three levels of fuel cycle management can be considered: 1) a long term management: determination of enrichments and expected cycle lengths, 2) a mid term management whose aim corresponds to the evaluation of the batch to load within the core as a function of both: the next cycle length to achieve and the integrated power history of all the cycles up to the present one, 3) a short term management which deals with the updating of the loaded fuel utilisations to take into account the operation perturbations, or with the alteration of the loading pattern of the next batch to respect unexpected conditions. (orig.) [de

  16. Rapsodie: A closed fuel cycle

    International Nuclear Information System (INIS)

    Levallet, E.H.; Costa, L.; Mougniot, J.C.; Robin, J.

    1977-01-01

    The Fortissimo Version of the core of the RAPSODIE fast reactor produces 40 MWTh. Since its start up in May 1970 in the CEN-CADARACHE its availability has stayed around 85%. Some of the mixed oxyde fuel pins UO 2 - 30% PuO 2 have already reached 150.000 MWd/t. The reprocessing is done in the pilot plant located in the La Hague Center and the plutonium obtained has already been re-used in the reactor. The Rapsodie-Fortissimo cycle is therefore now a closed cycle. This cycle is quite representative of fast reactor cycle characteristics and thus provides a remarkable research and development tool for the study of fabrication, in-reactor performances, transport, storage and reprocessing. These studies concern in particular the evolution of fission products and heavy isotopes content in fuel which controls both reprocessing schemes and intensity of emitted radiations. A program for the analysis of irradiated fuel has been developed either using samples collected all along the cycle, or following the actual reprocessing subassemblies. A set of basic data and calculation models has been established with two objectives: to give a better interpretation of the experimental program on one hand, and to extrapolate these results to the fuel cycle of fast reactors in general on the other hand. The first results have been quite encouraging up to now [fr

  17. Exergy optimization for a novel combination of organic Rankine cycles, Stirling cycle and direct expander turbines

    Science.gov (United States)

    Moghimi, Mahdi; Khosravian, Mohammadreza

    2018-06-01

    In this paper, a novel combination of organic Rankine cycles (ORCs), Stirling cycle and direct expander turbines is modeled and optimized using the genetic algorithm. The Exergy efficiency is considered as an objective function in the genetic algorithm. High efficiency is the main advantage of Stirling cycle, however, it needs nearly isothermal compressor and turbine. Therefore, an argon ORC and a R14 ORC are placed before and after the Striling cycle along with two expander turbines at the end of the line. Each component and cycle of the proposed plant in this article is verified by the previous works available in the literature and good agreement is achieved. The obtained results reveal that 27.98%, 20.86% and 12.90% of the total cold exergy are used by argon ORC, Stirling cycle and R14 ORC, respectively. Therefore, utilization of the Stirling cycle is a good idea for the LNG line cold exergy. The maximum exergy destruction occurs in the heat exchanger after the argon ORC (85.786 kJ/s per one kg/s LNG) due to the wasted cold exergy, which can be used for air conditioning systems in the plant. Finally, it would be shown that the maximum efficiency of the proposed plant is 54.25% and the maximum output power is 355.72 kW.

  18. Exergy optimization for a novel combination of organic Rankine cycles, Stirling cycle and direct expander turbines

    Science.gov (United States)

    Moghimi, Mahdi; Khosravian, Mohammadreza

    2018-01-01

    In this paper, a novel combination of organic Rankine cycles (ORCs), Stirling cycle and direct expander turbines is modeled and optimized using the genetic algorithm. The Exergy efficiency is considered as an objective function in the genetic algorithm. High efficiency is the main advantage of Stirling cycle, however, it needs nearly isothermal compressor and turbine. Therefore, an argon ORC and a R14 ORC are placed before and after the Striling cycle along with two expander turbines at the end of the line. Each component and cycle of the proposed plant in this article is verified by the previous works available in the literature and good agreement is achieved. The obtained results reveal that 27.98%, 20.86% and 12.90% of the total cold exergy are used by argon ORC, Stirling cycle and R14 ORC, respectively. Therefore, utilization of the Stirling cycle is a good idea for the LNG line cold exergy. The maximum exergy destruction occurs in the heat exchanger after the argon ORC (85.786 kJ/s per one kg/s LNG) due to the wasted cold exergy, which can be used for air conditioning systems in the plant. Finally, it would be shown that the maximum efficiency of the proposed plant is 54.25% and the maximum output power is 355.72 kW.

  19. Political Budget Cycles

    DEFF Research Database (Denmark)

    Aaskoven, Lasse; Lassen, David Dreyer

    2017-01-01

    The political budget cycle—how elections affect government fiscal policy—is one of the most studied subjects in political economy and political science. The key theoretical question is whether incumbent governments can time or structure public finances in ways that improve their chances of reelec......The political budget cycle—how elections affect government fiscal policy—is one of the most studied subjects in political economy and political science. The key theoretical question is whether incumbent governments can time or structure public finances in ways that improve their chances...... on political budget cycles have recently focused on conditions under which such cycles are likely to obtain. Much recent research focuses on subnational settings, allowing comparisons of governments in similar institutional environments, and a consensus on the presences of cycles in public finances...

  20. Combined Turbine and Cycle Optimization for Organic Rankine Cycle Power Systems—Part A

    DEFF Research Database (Denmark)

    Meroni, Andrea; La Seta, Angelo; Andreasen, Jesper Graa

    2016-01-01

    Axial-flow turbines represent a well-established technology for a wide variety of power generation systems. Compactness, flexibility, reliability and high efficiency have been key factors for the extensive use of axial turbines in conventional power plants and, in the last decades, in organic...... Rankine cycle power systems. In this two-part paper, an overall cycle model and a model of an axial turbine were combined in order to provide a comprehensive preliminary design of the organic Rankine cycle unit, taking into account both cycle and turbine optimal designs. Part A presents the preliminary...

  1. Primary granulocyte colony-stimulating factor prophylaxis during the first two cycles only or throughout all chemotherapy cycles in patients with breast cancer at risk for febrile neutropenia.

    Science.gov (United States)

    Aarts, Maureen J; Peters, Frank P; Mandigers, Caroline M; Dercksen, M Wouter; Stouthard, Jacqueline M; Nortier, Hans J; van Laarhoven, Hanneke W; van Warmerdam, Laurence J; van de Wouw, Agnes J; Jacobs, Esther M; Mattijssen, Vera; van der Rijt, Carin C; Smilde, Tineke J; van der Velden, Annette W; Temizkan, Mehmet; Batman, Erdogan; Muller, Erik W; van Gastel, Saskia M; Borm, George F; Tjan-Heijnen, Vivianne C G

    2013-12-01

    Early breast cancer is commonly treated with anthracyclines and taxanes. However, combining these drugs increases the risk of myelotoxicity and may require granulocyte colony-stimulating factor (G-CSF) support. The highest incidence of febrile neutropenia (FN) and largest benefit of G-CSF during the first cycles of chemotherapy lead to questions about the effectiveness of continued use of G-CSF throughout later cycles of chemotherapy. In a multicenter study, patients with breast cancer who were considered fit enough to receive 3-weekly polychemotherapy, but also had > 20% risk for FN, were randomly assigned to primary G-CSF prophylaxis during the first two chemotherapy cycles only (experimental arm) or to primary G-CSF prophylaxis throughout all chemotherapy cycles (standard arm). The noninferiority hypothesis was that the incidence of FN would be maximally 7.5% higher in the experimental compared with the standard arm. After inclusion of 167 eligible patients, the independent data monitoring committee advised premature study closure. Of 84 patients randomly assigned to G-CSF throughout all chemotherapy cycles, eight (10%) experienced an episode of FN. In contrast, of 83 patients randomly assigned to G-CSF during the first two cycles only, 30 (36%) had an FN episode (95% CI, 0.13 to 0.54), with a peak incidence of 24% in the third cycle (ie, first cycle without G-CSF prophylaxis). In patients with early breast cancer at high risk for FN, continued use of primary G-CSF prophylaxis during all chemotherapy cycles is of clinical relevance and thus cannot be abandoned.

  2. Very high cycle fatigue testing of concrete using ultrasonic cycling

    Energy Technology Data Exchange (ETDEWEB)

    Karr, Ulrike; Schuller, Reinhard; Fitzka, Michael; Mayer, Herwig [Univ. of Natural Resources and Life Sciences, Vienna (Austria). Inst. of Physics and Materials Science; Denk, Andreas; Strauss, Alfred [Univ. of Natural Resources and Life Sciences, Vienna (Austria)

    2017-06-01

    The ultrasonic fatigue testing method has been further developed to perform cyclic compression tests with concrete. Cylindrical specimens vibrate in resonance at a frequency of approximately 20 kHz with superimposed compressive static loads. The high testing frequency allows time-saving investigations in the very high cycle fatigue regime. Fatigue tests were carried out on ''Concrete 1'' (compressive strength f{sub c} = 80 MPa) and ''Concrete 2'' (f{sub c} = 107 MPa) under purely compressive loading conditions. Experiments at maximum compressive stresses of 0.44 f{sub c} (Concrete 1) and 0.38 f{sub c} (Concrete 2) delivered specimen failures above 109 cycles, indicating that no fatigue limit exists for concrete below one billion load cycles. Resonance frequency, power required to resonate the specimen and second order harmonics of the vibration are used to monitor fatigue damage in situ. Specimens were scanned by X-ray computed tomography prior to and after testing. Fatigue cracks were produced by ultrasonic cycling in the very high cycle fatigue regime at interfaces of grains as well as in cement. The possibilities as well as limitations of ultrasonic fatigue testing of concrete are discussed.

  3. Cycles and Common Cycles in Property and Related Sectors

    OpenAIRE

    Peijie Wang

    2003-01-01

    This paper examines cycles and common cycles in the property market and the economy. While focusing on common cycles, the study also incorporates common trends in the meantime, so it covers the whole spectrum of dynamic analysis. It has been found that property shares common cycles, particularly with those sectors that are the user markets of property. The mechanisms of common cycles and the relative magnitudes of cycles of the sectors related to property are discussed to shed light on proper...

  4. Natural cycle IVF with and without terminal HCG: learning from failed cycles.

    Science.gov (United States)

    Lenton, Elizabeth A

    2007-08-01

    Natural cycle IVF, without the use of LH down-regulation, is difficult because women start spontaneous LH surges at any time of the day and on any day of the week. This is not readily compatible with delivery of a routine IVF service and so historically the natural cycle has been modified by the use of human chorionic gonadotrophin (HCG) to make the natural cycle fit convenient clinical practice. This report re-evaluates data collected some years ago and seeks to determine whether the use of HCG is ultimately beneficial. Two large series of natural cycle IVF where only LH monitoring was performed (534 cycles) or where this was combined with HCG as necessary (241 cycles) were analysed. In essence, the use of HCG introduced as many problems as it overcame: there was no net benefit with respect to the number of eggs collected or clinical pregnancies generated. In fact there was an overall deterioration in all indices. The principle difficulties with natural cycle IVF are those associated with the prediction of follicle maturity and hence timing egg collection, and the conflict between costly and intrusively frequent monitoring with simpler but far less effective approaches.

  5. Small Engine Repair. Two-Stroke and Four-Stroke Cycle.

    Science.gov (United States)

    Hires, Bill; And Others

    This curriculum guide is intended to assist persons teaching a course in repairing two- and four-stroke cycle small engines. Addressed in the individual units of instruction are the following topics: safety, tools, fasteners, and measurement techniques; basic small engine theory (engine identification and inspection, basic engine principles and…

  6. Transcript-level annotation of Affymetrix probesets improves the interpretation of gene expression data

    Directory of Open Access Journals (Sweden)

    Tu Kang

    2007-06-01

    Full Text Available Abstract Background The wide use of Affymetrix microarray in broadened fields of biological research has made the probeset annotation an important issue. Standard Affymetrix probeset annotation is at gene level, i.e. a probeset is precisely linked to a gene, and probeset intensity is interpreted as gene expression. The increased knowledge that one gene may have multiple transcript variants clearly brings up the necessity of updating this gene-level annotation to a refined transcript-level. Results Through performing rigorous alignments of the Affymetrix probe sequences against a comprehensive pool of currently available transcript sequences, and further linking the probesets to the International Protein Index, we generated transcript-level or protein-level annotation tables for two popular Affymetrix expression arrays, Mouse Genome 430A 2.0 Array and Human Genome U133A Array. Application of our new annotations in re-examining existing expression data sets shows increased expression consistency among synonymous probesets and strengthened expression correlation between interacting proteins. Conclusion By refining the standard Affymetrix annotation of microarray probesets from the gene level to the transcript level and protein level, one can achieve a more reliable interpretation of their experimental data, which may lead to discovery of more profound regulatory mechanism.

  7. The life cycle of centrioles.

    Science.gov (United States)

    Hatch, E; Stearns, T

    2010-01-01

    Centrioles organize the centrosome and nucleate the ciliary axoneme, and the centriole life cycle has many parallels to the chromosome cycle. The centriole cycle in animals begins at fertilization with the contribution of two centrioles by the male gamete. In the ensuing cell cycles, the duplication of centrioles is controlled temporally, spatially, and numerically. As a consequence of the duplication mechanism, the two centrioles in a typical interphase cell are of different ages and have different functions. Here, we discuss how new centrioles are assembled, what mechanisms limit centriole number, and the consequences of the inherent asymmetry of centriole duplication and segregation.

  8. Advanced fuel cycles: a rationale and strategy for adopting the low-enriched-uranium fuel cycle

    International Nuclear Information System (INIS)

    James, R.A.

    1980-01-01

    A two-year study of alternatives to the natural uranium fuel cycle in CANDU reactors is summarized. The possible advanced cycles are briefly described. Selection criteria for choosing a cycle for development include resource utilization, economics, ease of implementaton, and social acceptability. It is recommended that a detailed study should be made with a view to the early implementation of the low-enriched uranium cycle. (LL)

  9. HCl removal using cycled carbide slag from calcium looping cycles

    International Nuclear Information System (INIS)

    Xie, Xin; Li, Yingjie; Wang, Wenjing; Shi, Lei

    2014-01-01

    Highlights: • Cycled carbide slag from calcium looping cycles is used to remove HCl. • The optimum temperature for HCl removal of cycled carbide slag is 700 °C. • The presence of CO 2 restrains HCl removal of cycled carbide slag. • CO 2 capture conditions have important effects on HCl removal of cycled carbide slag. • HCl removal capacity of carbide slag drops with cycle number rising from 1 to 50. - Abstract: The carbide slag is an industrial waste from chlor-alkali plants, which can be used to capture CO 2 in the calcium looping cycles, i.e. carbonation/calcination cycles. In this work, the cycled carbide slag from the calcium looping cycles for CO 2 capture was proposed to remove HCl in the flue gas from the biomass-fired and RDFs-fired boilers. The effects of chlorination temperature, HCl concentration, particle size, presence of CO 2 , presence of O 2 , cycle number and CO 2 capture conditions in calcium looping cycles on the HCl removal behavior of the carbide slag experienced carbonation/calcination cycles were investigated in a triple fixed-bed reactor. The chlorination product of the cycled carbide slag from the calcium looping after absorbing HCl is not CaCl 2 but CaClOH. The optimum temperature for HCl removal of the cycled carbide slag from the carbonation/calcination cycles is 700 °C. The chlorination conversion of the cycled carbide slag increases with increasing the HCl concentration. The cycled carbide slag with larger particle size exhibits a lower chlorination conversion. The presence of CO 2 decreases the chlorination conversions of the cycled carbide slag and the presence of O 2 has a trifling impact. The chlorination conversion of the carbide slag experienced 1 carbonation/calcination cycle is higher than that of the uncycled calcined sorbent. As the number of carbonation/calcination cycles increases from 1 to 50, the chlorination conversion of carbide slag drops gradually. The high calcination temperature and high CO 2

  10. CANDU fuel-cycle vision

    International Nuclear Information System (INIS)

    Boczar, P.G.

    1999-01-01

    The fuel-cycle path chosen by a particular country will depend on a range of local and global factors. The CANDU reactor provides the fuel-cycle flexibility to enable any country to optimize its fuel-cycle strategy to suit its own needs. AECL has developed the CANFLEX fuel bundle as the near-term carrier of advanced fuel cycles. A demonstration irradiation of 24 CANFLEX bundles in the Point Lepreau power station, and a full-scale critical heat flux (CHF) test in water are planned in 1998, before commercial implementation of CANFLEX fuelling. CANFLEX fuel provides a reduction in peak linear element ratings, and a significant enhancement in thermalhydraulic performance. Whereas natural uranium fuel provides many advantages, the use of slightly enriched uranium (SEU) in CANDU reactors offers even lower fuel-cycle costs and other benefits, such as uprating capability through flattening the channel power distribution across the core. Recycled uranium (RU) from reprocessing spent PWR fuel is a subset of SEU that has significant economic promise. AECL views the use of SEU/RU in the CANFLEX bundle as the first logical step from natural uranium. High neutron economy enables the use of low-fissile fuel in CANDU reactors, which opens up a spectrum of unique fuel-cycle opportunities that exploit the synergism between CANDU reactors and LWRs. At one end of this spectrum is the use of materials from conventional reprocessing: CANDU reactors can utilize the RU directly without re-enrichment, the plutonium as conventional Mixed-oxide (MOX) fuel, and the actinide waste mixed with plutonium in an inert-matrix carrier. At the other end of the spectrum is the DUPIC cycle, employing only thermal-mechanical processes to convert spent LWR fuel into CANDU fuel, with no purposeful separation of isotopes from the fuel, and possessing a high degree of proliferation resistance. Between these two extremes are other advanced recycling options that offer particular advantages in exploiting the

  11. CANDU fuel-cycle vision

    International Nuclear Information System (INIS)

    Boczar, P.G

    1998-05-01

    The fuel-cycle path chosen by a particular country will depend on a range of local and global factors. The CANDU reactor provides the fuel-cycle flexibility to enable any country to optimize its fuel-cycle strategy to suit its own needs. AECL has developed the CANFLEX fuel bundle as the near-term carrier of advanced fuel cycles. A demonstration irradiation of 24 CANFLEX bundles in the Point Lepreau power station, and a full-scale critical heat flux (CHF) test in water are planned in 1998, before commercial implementation of CANFLEX fuelling. CANFLEX fuel provides a reduction in peak linear element ratings, and a significant enhancement in thermalhydraulic performance. Whereas natural uranium fuel provides many advantages, the use of slightly enriched uranium (SEU) in CANDU reactors offers even lower fuel-cycle costs and other benefits, such as uprating capability through flattening the channel power distribution across the core. Recycled uranium (RU) from reprocessing spent PWR fuel is a subset of SEU that has significant economic promise. AECL views the use of SEU/RU in the CANFLEX bundle as the first logical step from natural uranium. High neutron economy enables the use of low-fissile fuel in CANDU reactors, which opens up a spectrum of unique fuel-cycle opportunities that exploit the synergism between CANDU reactors and LWRs. At one end of this spectrum is the use of materials from conventional reprocessing: CANDU reactors can utilize the RU directly without reenrichment, the plutonium as conventional mixed-oxide (MOX) fuel, and the actinide waste mixed with plutonium in an inert-matrix carrier. At the other end of the spectrum is the DUPIC cycle, employing only thermal-mechanical processes to convert spent LWR fuel into CANDU fuel, with no purposeful separation of isotopes from the fuel, and possessing a high degree of proliferation resistance. Between these two extremes are other advanced recycling options that offer particular advantages in exploiting the

  12. Life cycle replacement by gene introduction under an allee effect in periodical cicadas.

    Science.gov (United States)

    Nariai, Yukiko; Hayashi, Saki; Morita, Satoru; Umemura, Yoshitaka; Tainaka, Kei-ichi; Sota, Teiji; Cooley, John R; Yoshimura, Jin

    2011-04-06

    Periodical cicadas (Magicicada spp.) in the USA are divided into three species groups (-decim, -cassini, -decula) of similar but distinct morphology and behavior. Each group contains at least one species with a 17-year life cycle and one with a 13-year cycle; each species is most closely related to one with the other cycle. One explanation for the apparent polyphyly of 13- and 17-year life cycles is that populations switch between the two cycles. Using a numerical model, we test the general feasibility of life cycle switching by the introduction of alleles for one cycle into populations of the other cycle. Our results suggest that fitness reductions at low population densities of mating individuals (the Allee effect) could play a role in life cycle switching. In our model, if the 13-year cycle is genetically dominant, a 17-year cycle population will switch to a 13-year cycle given the introduction of a few 13-year cycle alleles under a moderate Allee effect. We also show that under a weak Allee effect, different year-classes ("broods") with 17-year life cycles can be generated. Remarkably, the outcomes of our models depend only on the dominance relationships of the cycle alleles, irrespective of any fitness advantages.

  13. Life cycle replacement by gene introduction under an allee effect in periodical cicadas.

    Directory of Open Access Journals (Sweden)

    Yukiko Nariai

    2011-04-01

    Full Text Available Periodical cicadas (Magicicada spp. in the USA are divided into three species groups (-decim, -cassini, -decula of similar but distinct morphology and behavior. Each group contains at least one species with a 17-year life cycle and one with a 13-year cycle; each species is most closely related to one with the other cycle. One explanation for the apparent polyphyly of 13- and 17-year life cycles is that populations switch between the two cycles. Using a numerical model, we test the general feasibility of life cycle switching by the introduction of alleles for one cycle into populations of the other cycle. Our results suggest that fitness reductions at low population densities of mating individuals (the Allee effect could play a role in life cycle switching. In our model, if the 13-year cycle is genetically dominant, a 17-year cycle population will switch to a 13-year cycle given the introduction of a few 13-year cycle alleles under a moderate Allee effect. We also show that under a weak Allee effect, different year-classes ("broods" with 17-year life cycles can be generated. Remarkably, the outcomes of our models depend only on the dominance relationships of the cycle alleles, irrespective of any fitness advantages.

  14. The cell cycle-regulated genes of Schizosaccharomyces pombe.

    Science.gov (United States)

    Oliva, Anna; Rosebrock, Adam; Ferrezuelo, Francisco; Pyne, Saumyadipta; Chen, Haiying; Skiena, Steve; Futcher, Bruce; Leatherwood, Janet

    2005-07-01

    Many genes are regulated as an innate part of the eukaryotic cell cycle, and a complex transcriptional network helps enable the cyclic behavior of dividing cells. This transcriptional network has been studied in Saccharomyces cerevisiae (budding yeast) and elsewhere. To provide more perspective on these regulatory mechanisms, we have used microarrays to measure gene expression through the cell cycle of Schizosaccharomyces pombe (fission yeast). The 750 genes with the most significant oscillations were identified and analyzed. There were two broad waves of cell cycle transcription, one in early/mid G2 phase, and the other near the G2/M transition. The early/mid G2 wave included many genes involved in ribosome biogenesis, possibly explaining the cell cycle oscillation in protein synthesis in S. pombe. The G2/M wave included at least three distinctly regulated clusters of genes: one large cluster including mitosis, mitotic exit, and cell separation functions, one small cluster dedicated to DNA replication, and another small cluster dedicated to cytokinesis and division. S. pombe cell cycle genes have relatively long, complex promoters containing groups of multiple DNA sequence motifs, often of two, three, or more different kinds. Many of the genes, transcription factors, and regulatory mechanisms are conserved between S. pombe and S. cerevisiae. Finally, we found preliminary evidence for a nearly genome-wide oscillation in gene expression: 2,000 or more genes undergo slight oscillations in expression as a function of the cell cycle, although whether this is adaptive, or incidental to other events in the cell, such as chromatin condensation, we do not know.

  15. A comparison of advanced heat recovery power cycles in a combined cycle for large ships

    International Nuclear Information System (INIS)

    Larsen, Ulrik; Sigthorsson, Oskar; Haglind, Fredrik

    2014-01-01

    Strong motivation exists within the marine sector to reduce fuel expenses and to comply with ever stricter emission regulations. Heat recovery can address both of these issues. The ORC (organic Rankine cycle), the Kalina cycle and the steam Rankine cycle have received the majority of the focus in the literature. In the present work we compare these cycles in a combined cycle application with a large marine two-stroke diesel engine. We present an evaluation of the efficiency and the environmental impact, safety concerns and practical aspects of each of the cycles. A previously validated numerical engine model is combined with a turbocharger model and bottoming cycle models written in Matlab. Genetic algorithm optimisation results suggest that the Kalina cycle possess no significant advantages compared to the ORC or the steam cycle. While contributing to very high efficiencies, the organic working fluids possess high global warming potentials and hazard levels. It is concluded that the ORC has the greatest potential for increasing the fuel efficiency, and the combined cycle offers very high thermal efficiency. While being less efficient, the steam cycle has the advantages of being well proven, harmless to the environment as well as being less hazardous in comparison. - Highlights: • We compare steam, ORC (organic Rankine cycle) and Kalina cycles for waste heat recovery in marine engines. • We evaluate the efficiency and important qualitative differences. • The Kalina cycle presents no apparent advantages. • The steam cycle is well known, harmless and has a high efficiency. • The ORC has the highest efficiency but also important drawbacks

  16. Life Cycle Sustainability Dashboard

    DEFF Research Database (Denmark)

    Traverso, Marzia; Finkbeiner, Matthias; Jørgensen, Andreas

    2012-01-01

    One method to assess the sustainability performance of products is life cycle sustainability assessment (LCSA), which assesses product performance considering the environmental,economic, and social dimensions of the life cycle. The results of LCSA can be used to compare different products...... of sustainability is the communicability of the results by means of a graphical representation (a cartogram), characterized by a suitable chromatic scale and ranking score. The integration of LCSA and the dashboard of sustainability into a so-called Life Cycle Sustainability Dashboard (LCSD) is described here...

  17. The Relationship between Inner Product and Counting Cycles

    DEFF Research Database (Denmark)

    Sun, Xiaoming; Wang, Chengu; Yu, Wei

    2012-01-01

    lower bounds in the streaming model for the Connectivity, Bipartiteness and Girth problems [7]. The inner product variant we used has a quantum lower bound of Ω(nlogp(m)), where p(m) is the smallest prime factor of m. It implies that our lower bounds for Cycle-Counting and related problems still hold......Cycle-Counting is the following communication complexity problem: Alice and Bob each holds a permutation of size n with the promise there will be either a cycles or b cycles in their product. They want to distinguish between these two cases by communicating a few bits. We show that the quantum....../nondeterministic communication complexity is roughly Ω˜((n−b)/(b−a)) when a≡b(mod2) . It is proved by reduction from a variant of the inner product problem over ℤ m . It constructs a bridge for various problems, including In-Same-Cycle [10], One-Cycle [14], and Bipartiteness on constant degree graph [9]. We also give space...

  18. Sometimes "Newton's Method" Always "Cycles"

    Science.gov (United States)

    Latulippe, Joe; Switkes, Jennifer

    2012-01-01

    Are there functions for which Newton's method cycles for all non-trivial initial guesses? We construct and solve a differential equation whose solution is a real-valued function that two-cycles under Newton iteration. Higher-order cycles of Newton's method iterates are explored in the complex plane using complex powers of "x." We find a class of…

  19. International Business Cycle Accounting

    OpenAIRE

    Keisuke Otsu

    2009-01-01

    In this paper, I extend the business cycle accounting method a la Chari, Kehoe and McGrattan (2007) to a two-country international business cycle model and quantify the effect of the disturbances in relevant markets on the business cycle correlation between Japan and the US over the 1980-2008 period. This paper finds that disturbances in the labor market and production efficiency are important in accounting for the recent increase in the cross-country output correlation. If international fina...

  20. Over view of nuclear fuel cycle examination facility at KAERI

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Key-Soon; Kim, Eun-Ga; Joe, Kih-Soo; Kim, Kil-Jeong; Kim, Ki-Hong; Min, Duk-Ki [Korea Atomic Energy Research Institute, Taejon (Korea)

    1999-09-01

    Nuclear fuel cycle examination facilities at the Korea Atomic Energy Research Institute (KAERI) consist of two post-irradiation examination facilities (IMEF and PIEF), one chemistry research facility (CRF), one radiowaste treatment facility (RWTF) and one radioactive waste form examination facility (RWEF). This paper presents the outline of the nuclear fuel cycle examination facilities in KAERI. (author)

  1. Molecular signature of cell cycle exit induced in human T lymphoblasts by IL-2 withdrawal

    Directory of Open Access Journals (Sweden)

    Pfeifer Aleksandra

    2009-06-01

    Full Text Available Abstract Background The molecular mechanisms of cell cycle exit are poorly understood. Studies on lymphocytes at cell cycle exit after growth factor deprivation have predominantly focused on the initiation of apoptosis. We aimed to study gene expression profile of primary and immortalised IL-2-dependent human T cells forced to exit the cell cycle by growth factor withdrawal, before apoptosis could be evidenced. Results By the Affymetrix microarrays HG-U133 2.0 Plus, 53 genes were distinguished as differentially expressed before and soon after IL-2 deprivation. Among those, PIM1, BCL2, IL-8, HBEGF, DUSP6, OSM, CISH, SOCS2, SOCS3, LIF and IL13 were down-regulated and RPS24, SQSTM1, TMEM1, LRRC8D, ECOP, YY1AP1, C1orf63, ASAH1, SLC25A46 and MIA3 were up-regulated. Genes linked to transcription, cell cycle, cell growth, proliferation and differentiation, cell adhesion, and immune functions were found to be overrepresented within the set of the differentially expressed genes. Conclusion Cell cycle exit of the growth factor-deprived T lymphocytes is characterised by a signature of differentially expressed genes. A coordinate repression of a set of genes known to be induced during T cell activation is observed. However, growth arrest following exit from the cell cycle is actively controlled by several up-regulated genes that enforce the non-dividing state. The identification of genes involved in cell cycle exit and quiescence provides new hints for further studies on the molecular mechanisms regulating the non-dividing state of a cell, the mechanisms closely related to cancer development and to many biological processes.

  2. A two-level strategy to realize life-cycle production optimization in an operational setting

    NARCIS (Netherlands)

    Essen, van G.M.; Hof, Van den P.M.J.; Jansen, J.D.

    2012-01-01

    We present a two-level strategy to improve robustness against uncertainty and model errors in life-cycle flooding optimization. At the upper level, a physics-based large-scale reservoir model is used to determine optimal life-cycle injection and production profiles. At the lower level these profiles

  3. A two-level strategy to realize life-cycle production optimization in an operational setting

    NARCIS (Netherlands)

    Essen, van G.M.; Hof, Van den P.M.J.; Jansen, J.D.

    2013-01-01

    We present a two-level strategy to improve robustness against uncertainty and model errors in life-cycle flooding optimization. At the upper level, a physics-based large-scale reservoir model is used to determine optimal life-cycle injection and production profiles. At the lower level these profiles

  4. KOH concentration effect on cycle life of nickel-hydrogen cells

    Science.gov (United States)

    Lim, Hong S.; Verzwyvelt, S. A.

    1987-01-01

    A cycle life test of Ni/H2 cells containing electrolytes of various KOH concentrations and a sintered type nickel electrode was carried out at 23 C using a 45 min accelerated low Earth orbit (LEO) cycle regime at 80 percent depth of discharge. One of three cells containing 26 percent KOH has achieved over 28,000 cycles, and the other two 19,000 cycles, without a sign of failure. Two other cells containing 31 percent KOH electrolyte, which is the concentration presently used in aerospace cells, failed after 2,979 and 3,620 cycles. This result indicates that the cycle life of the present type of Ni/H2 cells may be extended by a factor of 5 to 10 simply by lowering the KOH concentration. Long cycle life of a Ni/H2 battery at high depth-of-discharge operation is desired, particularly for an LEO spacecraft application. Typically, battery life of about 30,000 cycles is required for a five year mission in an LEO. Such a cycle life with presently available cells can be assured only at a very low depth-of-discharge operation. Results of testing already show that the cycle life of an Ni/H2 cell is tremendously improved by simply using an electrolyte of low KOH concentration.

  5. The cell cycle-regulated genes of Schizosaccharomyces pombe.

    Directory of Open Access Journals (Sweden)

    Anna Oliva

    2005-07-01

    Full Text Available Many genes are regulated as an innate part of the eukaryotic cell cycle, and a complex transcriptional network helps enable the cyclic behavior of dividing cells. This transcriptional network has been studied in Saccharomyces cerevisiae (budding yeast and elsewhere. To provide more perspective on these regulatory mechanisms, we have used microarrays to measure gene expression through the cell cycle of Schizosaccharomyces pombe (fission yeast. The 750 genes with the most significant oscillations were identified and analyzed. There were two broad waves of cell cycle transcription, one in early/mid G2 phase, and the other near the G2/M transition. The early/mid G2 wave included many genes involved in ribosome biogenesis, possibly explaining the cell cycle oscillation in protein synthesis in S. pombe. The G2/M wave included at least three distinctly regulated clusters of genes: one large cluster including mitosis, mitotic exit, and cell separation functions, one small cluster dedicated to DNA replication, and another small cluster dedicated to cytokinesis and division. S. pombe cell cycle genes have relatively long, complex promoters containing groups of multiple DNA sequence motifs, often of two, three, or more different kinds. Many of the genes, transcription factors, and regulatory mechanisms are conserved between S. pombe and S. cerevisiae. Finally, we found preliminary evidence for a nearly genome-wide oscillation in gene expression: 2,000 or more genes undergo slight oscillations in expression as a function of the cell cycle, although whether this is adaptive, or incidental to other events in the cell, such as chromatin condensation, we do not know.

  6. Will Solar Cycles 25 and 26 Be Weaker than Cycle 24?

    Science.gov (United States)

    Javaraiah, J.

    2017-11-01

    The study of variations in solar activity is important for understanding the underlying mechanism of solar activity and for predicting the level of activity in view of the activity impact on space weather and global climate. Here we have used the amplitudes (the peak values of the 13-month smoothed international sunspot number) of Solar Cycles 1 - 24 to predict the relative amplitudes of the solar cycles during the rising phase of the upcoming Gleissberg cycle. We fitted a cosine function to the amplitudes and times of the solar cycles after subtracting a linear fit of the amplitudes. The best cosine fit shows overall properties (periods, maxima, minima, etc.) of Gleissberg cycles, but with large uncertainties. We obtain a pattern of the rising phase of the upcoming Gleissberg cycle, but there is considerable ambiguity. Using the epochs of violations of the Gnevyshev-Ohl rule (G-O rule) and the `tentative inverse G-O rule' of solar cycles during the period 1610 - 2015, and also using the epochs where the orbital angular momentum of the Sun is steeply decreased during the period 1600 - 2099, we infer that Solar Cycle 25 will be weaker than Cycle 24. Cycles 25 and 26 will have almost same strength, and their epochs are at the minimum between the current and upcoming Gleissberg cycles. In addition, Cycle 27 is expected to be stronger than Cycle 26 and weaker than Cycle 28, and Cycle 29 is expected to be stronger than both Cycles 28 and 30. The maximum of Cycle 29 is expected to represent the next Gleissberg maximum. Our analysis also suggests a much lower value (30 - 40) for the maximum amplitude of the upcoming Cycle 25.

  7. Culture in cycles: considering H.T. Odum's 'information cycle'

    Science.gov (United States)

    Abel, Thomas

    2014-01-01

    'Culture' remains a conundrum in anthropology. When recast in the mold of 'information cycles,' culture is transformed. New fault lines appear. Information is splintered into parallel or nested forms. Dynamics becomes cycling. Energy is essential. And culture has function in a directional universe. The 'information cycle' is the crowning component of H.T. Odum's theory of general systems. What follows is an application of the information cycle to the cultural domains of discourse, social media, ritual, education, journalism, technology, academia, and law, which were never attempted by Odum. In information cycles, cultural information is perpetuated - maintained against Second Law depreciation. Conclusions are that culture is in fact a nested hierarchy of cultural forms. Each scale of information production is semi-autonomous, with its own evolutionary dynamics of production and selection in an information cycle. Simultaneously, each information cycle is channeled or entrained by its larger scale of information and ultimately human-ecosystem structuring.

  8. Comparison of several hydrological cycle parameters in Croatia for two periods

    International Nuclear Information System (INIS)

    Pandzic, Kreso; Trninic, Dusan

    2004-01-01

    Comparison of several hydrological cycle parameter averages for two periods in Croatia is considered. Parameters are: yearly averages of: 2m air temperature, precipitation amounts, potential and real evapotranspiration amounts. A basic period (1951-1980) and period for comparison (1981-1997) have been chosen. (These periods accepted at The First Sub-Regional Expert Meeting on the 'Assesment of Climate Change Impacts on the Hydrological Cycles in South-Eastern Europe' held in Sofia (Bulgaria) 17-20 February 1999.) Differences between two period averages for 30 weather stations have been calculated. Temperature differences and those for potential evaporation are positive while for precipitation they are mainly negative. Real evaporation differences for two periods are an exception i.e. they are positive in continental but negative in Mediterranean part of Croatia. These results agree with global warming trend. (Author)

  9. Enhanced degradation of 14C-HCB in two tropical clay soils using multiple anaerobic–aerobic cycles

    International Nuclear Information System (INIS)

    Orori Kengara, Fredrick; Doerfler, Ulrike; Welzl, Gerhard; Ruth, Bernhard; Munch, Jean Charles; Schroll, Reiner

    2013-01-01

    The aim of the study was to induce and enhance the degradation of hexachlorobenzene (HCB), a highly-chlorinated persistent organic pollutant, in two ecologically different tropical soils: a paddy soil (PS) and a non-paddy soil (FS). The degradation of HCB was enhanced using two anaerobic–aerobic cycles in model laboratory experiments. There was greater degradation of HCB in the PS (half-life of 224 days) relative to the FS (half-life of 286 days). It was further shown that soils amended with compost had higher metabolite concentrations relative to the non-amended soils. In the first cycle, there was little degradation of HCB in both soils. However, in the second cycle, there was enhanced mineralization in the PS under aerobic conditions, with the compost-treated samples showing higher mineralization. There was also extensive volatilization in both soils. The metabolite pattern revealed that the increased mineralization and volatilization was due to the formation of lower chlorinated benzenes. - Highlights: ► Two anaerobic–aerobic cycles enhanced the dissipation of HCB in two tropical soils – a paddy and non-paddy soil. ► The paddy soil was more effective in degrading HCB. ► The non-paddy soil adapted and degraded HCB in the second anaerobic–aerobic cycle. ► An additional carbon source enhanced degradation and mineralisation of HCB in both soils. - Two anaerobic–aerobic cycles enhance the degradation of HCB in two ecologically different tropical clay soils.

  10. Interrelations between random walks on diagrams (graphs) with and without cycles.

    Science.gov (United States)

    Hill, T L

    1988-05-01

    Three topics are discussed. A discrete-state, continuous-time random walk with one or more absorption states can be studied by a presumably new method: some mean properties, including the mean time to absorption, can be found from a modified diagram (graph) in which each absorption state is replaced by a one-way cycle back to the starting state. The second problem is a random walk on a diagram (graph) with cycles. The walk terminates on completion of the first cycle. This walk can be replaced by an equivalent walk on a modified diagram with absorption. This absorption diagram can in turn be replaced by another modified diagram with one-way cycles back to the starting state, just as in the first problem. The third problem, important in biophysics, relates to a long-time continuous walk on a diagram with cycles. This diagram can be transformed (in two steps) to a modified, more-detailed, diagram with one-way cycles only. Thus, the one-way cycle fluxes of the original diagram can be found from the state probabilities of the modified diagram. These probabilities can themselves be obtained by simple matrix inversion (the probabilities are determined by linear algebraic steady-state equations). Thus, a simple method is now available to find one-way cycle fluxes exactly (previously Monte Carlo simulation was required to find these fluxes, with attendant fluctuations, for diagrams of any complexity). An incidental benefit of the above procedure is that it provides a simple proof of the one-way cycle flux relation Jn +/- = IIn +/- sigma n/sigma, where n is any cycle of the original diagram.

  11. Role of the seasonal cycle in coupling climate and carbon cycling in subanartic zone

    CSIR Research Space (South Africa)

    Monteiro, PMS

    2010-08-01

    Full Text Available There is increasing evidence in the Southern Ocean that mesoscales and seasonal scales play an important role in the coupling of ocean carbon cycling and climate. The seasonal cycle is one of the strongest modes of variability in different...

  12. Life Cycle Assessment of two Electrolux electric cookers: ELK8200AL and EKV5600

    DEFF Research Database (Denmark)

    Hansen, Morten Søes; Wenzel, Henrik; Frees, Niels

    A life cycle assessment of two electrical cookers was made for the company Electrolux A/S. A number of valid conclusions can be drawn from the study. The conclusions are supported by a sensitivity analysis covering essential parameter variations and showing that quite robust conclusions can...... issue for the resource consumption of the cookers over their life cycle • Transportation of the cookers over their life cycle is insignificant Environmentally, the main perspectives for improvements lie in the optimisation of the use stage, including better efficiency in transformation of the energy...

  13. The influence of sporadic anovulation on hormone levels in ovulatory cycles

    Science.gov (United States)

    Hambridge, H.L.; Mumford, S.L.; Mattison, D.R.; Ye, A.; Pollack, A.Z.; Bloom, M.S.; Mendola, P.; Lynch, K.L.; Wactawski-Wende, J.; Schisterman, E.F.

    2013-01-01

    STUDY QUESTION Do ovulatory hormone profiles among healthy premenopausal women differ between women with and without sporadic anovulation? SUMMARY ANSWER Women with one anovulatory cycle tended to have lower estradiol, progesterone and LH peak levels during their ovulatory cycle. WHAT IS KNOWN ALREADY Anovulation occurs sporadically in healthy premenopausal women, but the influence of hormones in a preceding cycle and the impact on a subsequent cycle's hormone levels is unknown. STUDY DESIGN, SIZE, DURATION The BioCycle Study was a prospective cohort including 250 healthy regularly menstruating women, 18–44 years of age, from Western New York with no history of menstrual or ovulation disorders. The women were followed with up to eight study visits per cycle for two cycles, most of which were consecutive. PARTICIPANTS/MATERIALS, SETTING AND METHODS All study visits were timed to menstrual cycle phase using fertility monitors and located at the University at Buffalo women's health research center from 2005 to 2007. The main outcomes measured were estradiol, progesterone, LH and follicle-stimulating hormone levels in serum at up to 16 visits over two cycles. Anovulation was defined as peak serum progesterone concentrations ≤5 ng/ml and no serum LH peak detected during the mid- or late-luteal phase visit. MAIN RESULTS AND THE ROLE OF CHANCE Reproductive hormone concentrations were lower during anovulatory cycles, but significant reductions were also observed in estradiol (−25%, P = 0.003) and progesterone (−22%, P = 0.001) during the ovulatory cycles of women with one anovulatory cycle compared with women with two ovulatory cycles. LH peak concentrations were decreased in the ovulatory cycle of women with an anovulatory cycle (significant amplitude effect, P = 0.004; geometric mean levels 38% lower, P cycles, and no ultrasound assessment of ovulation was available. Data were missing for a total of 168 of a possible 4072 cycle visits (4.1%), though all women had

  14. The phylogeny and life cycle of two species of Profilicollis (Acanthocephala: Polymorphidae) in marine hosts off the Pacific coast of Chile.

    Science.gov (United States)

    Rodríguez, S M; D'Elía, G; Valdivia, N

    2017-09-01

    Resolving complex life cycles of parasites is a major goal of parasitological research. The aim of this study was to analyse the life cycle of two species of the genus Profilicollis, the taxonomy of which is still unstable and life cycles unclear. We extracted individuals of Profilicollis from two species of crustaceans (intermediate hosts) and four species of seagulls (definitive hosts) from sandy-shore and estuarine habitats along the south-east Pacific coast of Chile. Mitochondrial DNA analyses showed that two species of Profilicollis infected intermediate hosts from segregated habitats: while P. altmani larvae infected exclusively molecrabs of the genus Emerita from fully marine habitats, P. antarcticus larvae infected the crab Hemigrapsus crenulatus from estuarine habitats. Moreover, P. altmani completed its life cycle in four seagulls, Chroicocephalus maculipennis, Leucopheus pipixcan, Larus modestus and L. dominicanus, while P. antarcticus, on the other hand, completed its life cycle in the kelp gull L. dominicanus. Accordingly, our results show that two congeneric parasites use different and spatially segregated species as intermediate hosts, and both are capable of infecting one species of definitive hosts. As such, our analyses allow us to shed light on a complex interaction network.

  15. Variable geometry gas turbines for improving the part-load performance of marine combined cycles - Combined cycle performance

    DEFF Research Database (Denmark)

    Haglind, Fredrik

    2011-01-01

    The part-load performance of combined cycles intended for naval use is of great importance, and it is influenced by the gas turbine configuration and load control strategy. This paper is aimed at quantifying the effects of variable geometry gas turbines on the part-load efficiency for combined...... cycles used for ship propulsion. Moreover, the paper is aimed at developing methodologies and deriving models for part-load simulations suitable for energy system analysis of various components within combined cycle power plants. Two different gas turbine configurations are studied, a two-shaft aero......-derivative configuration and a single-shaft industrial configuration. The results suggest that by the use of variable geometry gas turbines, the combined cycle part-load performance can be improved. In order to minimise the voyage fuel consumption, a combined cycle featuring two-shaft gas turbines with VAN control...

  16. On Acyclicity of Games with Cycles

    DEFF Research Database (Denmark)

    Andersson, Daniel; Gurvich, Vladimir; Hansen, Thomas Dueholm

    2009-01-01

    We study restricted improvement cycles (ri-cycles) in finite positional n-person games with perfect information modeled by directed graphs (digraphs) that may contain cycles. We obtain criteria of restricted improvement acyclicity (ri-acyclicity) in two cases: for n = 2 and for acyclic digraphs. We...

  17. Cumulative live birth rates after one or more complete cycles of IVF: a population-based study of linked cycle data from 178,898 women.

    Science.gov (United States)

    McLernon, David J; Maheshwari, Abha; Lee, Amanda J; Bhattacharya, Siladitya

    2016-03-01

    What is the chance of a live birth following one or more linked complete cycles of IVF (including ICSI)? The chance of a live birth after three complete cycles of IVF was 42.3% for treatment commencing from 1999 to 2007. IVF success has generally been reported on the basis of live birth rates after a single episode of treatment resulting in the transfer of a fresh embryo. This fails to capture the real chance of having a baby after a number of complete cycles-each involving the replacement of fresh as well as frozen-thawed embryos. Population-based observational cohort study of 178 898 women between 1992 and 2007. Participants included all women who commenced IVF treatment at a licenced clinic in the UK as recorded in the Human Fertilisation and Embryology Authority (HFEA) national database. Exclusion criteria included women whose treatment involved donor insemination, egg donation, surrogacy and the transfer of more than three embryos. Cumulative rates of live birth, term (>37 weeks) singleton live birth, and multiple pregnancy were estimated for two time-periods, 1992-1998 and 1999-2007. Conservative estimates assumed that women who did not return for IVF would not have the outcome of interest while optimal estimates assumed that these women would have similar outcome rates to those who continued IVF. A total of 71 551 women commenced IVF treatment during 1992-1998 and an additional 107 347 during 1999-2007. After the third complete IVF cycle (defined as three fresh IVF treatments-including replacement of any surplus frozen-thawed embryos), the conservative CLBR in women who commenced IVF during 1992-1998 was 30.8% increasing to 42.3% during 1999-2007. The optimal CLBRs were 44.6 and 57.1%, respectively. After eight complete cycles the optimal CLBR was 82.4% in the latter time period. The conservative rate for multiple pregnancy per pregnant woman fell from 31.9% during the earlier time period to 26.2% during the latter. Linkage of all IVF treatments to

  18. Has accession to the EU affected business cycles?

    Directory of Open Access Journals (Sweden)

    Panagiotis EVANGELOPOULOS

    2013-02-01

    Full Text Available This paper undertakes to explain the relationship between EU accession and the length of business cycles, focusing specifically on whether participation in a multinational organization has, or has not, altered the length of the cycle. Employing a sample of nine EU countries (Austria, Denmark, Finland, Greece, Ireland, Portugal, Spain, Sweden and the UK we focused initially on annual data for per capita growth in GDP over a period of 59 years (1950-2008. For each country the sample was divided into two parts, one covering the period preceding accession to the EU and one is covering the accession year and succeeding years. Then, eliminating the background noise with the use of a periodogram, we proceeded to examine their spectral density plots. The results indicated that in the first years following accession, the countries tended to experience shorter cycles than they had previously. In the second phase the cycles were of the same duration as previous cycles. Finally, after a period of some years, the length of the cycles increased, as suggested by the J-shaped curve. This J-shaped growth curve applies for the countries that have joined the EU, strongly suggesting a causal relationship between accession to the EU and these specific characterristics of the curve. We cross-checked with a set of four non-EU member countries (Iceland, Norway, Switzerland and Turkey and found no change in the length of the business cycle in these countries.

  19. Metabolic Interaction between Urea Cycle and Citric Acid Cycle Shunt: A Guided Approach

    Science.gov (United States)

    Pesi, Rossana; Balestri, Francesco; Ipata, Piero L.

    2018-01-01

    This article is a guided pedagogical approach, devoted to postgraduate students specializing in biochemistry, aimed at presenting all single reactions and overall equations leading to the metabolic interaction between ureagenesis and citric acid cycle to be incorporated into a two-three lecture series about the interaction of urea cycle with other…

  20. Combined rankine and vapor compression cycles

    Science.gov (United States)

    Radcliff, Thomas D.; Biederman, Bruce P.; Brasz, Joost J.

    2005-04-19

    An organic rankine cycle system is combined with a vapor compression cycle system with the turbine generator of the organic rankine cycle generating the power necessary to operate the motor of the refrigerant compressor. The vapor compression cycle is applied with its evaporator cooling the inlet air into a gas turbine, and the organic rankine cycle is applied to receive heat from a gas turbine exhaust to heat its boiler within one embodiment, a common condenser is used for the organic rankine cycle and the vapor compression cycle, with a common refrigerant, R-245a being circulated within both systems. In another embodiment, the turbine driven generator has a common shaft connected to the compressor to thereby eliminate the need for a separate motor to drive the compressor. In another embodiment, an organic rankine cycle system is applied to an internal combustion engine to cool the fluids thereof, and the turbo charged air is cooled first by the organic rankine cycle system and then by an air conditioner prior to passing into the intake of the engine.

  1. Your Menstrual Cycle

    Science.gov (United States)

    ... your menstrual cycle What happens during your menstrual cycle The menstrual cycle includes not just your period, but the rise ... that take place over the weeks in your cycle. Want to know what happens on each day ...

  2. Generalization of the Rabi population inversion dynamics in the sub-one-cycle pulse limit

    International Nuclear Information System (INIS)

    Doslic, N.

    2006-01-01

    We consider the population inversion in a two-level system generated by a sub-one-cycle pulse excitation. Specifically, we explore the effect that the time derivative of the pulse envelope has on the Rabi dynamics. Our analysis is based on a combination of analytical, perturbative, and nonperturbative treatments and is complemented by numerical simulations. We find a shortening of the Rabi inversion period and show that complete inversion is unobtainable under resonant, ultrashort pulse conditions. The impact of nonresonant and carrier-envelope phase-dependent effects on the dynamics of two-level and multilevel systems is studied numerically, and conditions for complete population inversion are derived

  3. CHOOSING DRIVING CYCLE OF HYBRID VEHICLE

    Directory of Open Access Journals (Sweden)

    A. Vorona

    2011-01-01

    Full Text Available The analysis of existing driving cycles was performed. After comparing some of the cycles, one specific driving cycle was selected for the hybrid vehicle as the most reliable in representing the real moving of the vehicle in operating conditions and which may be reproduced at experimental tests at the modeling roller stand.

  4. Growth scenarios with thorium fuel cycles in pressurised heavy water reactors

    International Nuclear Information System (INIS)

    Balakrishnan, M.R.

    1991-01-01

    Since India has generous deposits of thorium, the availability of thorium will not be a limiting factor in any growth scenario. It is fairly well accepted that the best system for utilisation of thorium is the heavy water reactor. The growth scenarios possible using thorium in HWRs are considered. The base has been taken as 50,000 tons of natural uranium and practically unlimited thorium. The reference reactor has been assumed to be the PHWR, and all other growth scenarios are compared with the growth scenario provided by the once-through natural cycle in the PHWR. Two reactor types have been considered: the heavy water moderated, heavy water cooled, pressure tube reactor, known as the PHWR; and the heavy water moderated and cooled pressure vessel kind, similar to the ATUCHA reactor in Argentina. For each reactor, a number of different fuel cycles have been studied. All these cycles have been based on thorium. These are: the self-sustaining equilibrium thorium cycle (SSET); the high conversion ratio high burnup cycle; and the once through thorium cycle (OTT). The cycle have been initiated in two ways: one is by starting the cycle with natural uranium, reprocessing the spent fuel to obtain plutonium, and use that plutonium to initiate the thorium cycle; the other is to enrich the uranium to about 2-3% U-235 (the so-called Low Enriched Uranium or LEU), and use the LEU to initiate the thorium cycle. Both cases have been studied, and growth scenarios have been projected for every one of the possible combinations. (author). 1 tab

  5. 40 CFR 89.410 - Engine test cycle.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 20 2010-07-01 2010-07-01 false Engine test cycle. 89.410 Section 89... Procedures § 89.410 Engine test cycle. (a) Emissions shall be measured using one of the test cycles specified...) through (a)(4) of this section. These cycles shall be used to test engines on a dynamometer. (1) The 8...

  6. Integrated solar thermal Brayton cycles with either one or two regenerative heat exchangers for maximum power output

    International Nuclear Information System (INIS)

    Jansen, E.; Bello-Ochende, T.; Meyer, J.P.

    2015-01-01

    The main objective of this paper is to optimise the open-air solar-thermal Brayton cycle by considering the implementation of the second law of thermodynamics and how it relates to the design of the heat exchanging components within it. These components included one or more regenerators (in the form of cross-flow heat exchangers) and the receiver of a parabolic dish concentrator where the system heat was absorbed. The generation of entropy was considered as it was associated with the destruction of exergy or available work. The dimensions of some components were used to optimise the cycles under investigation. EGM (Entropy Generation Minimisation) was employed to optimise the system parameters by considering their influence on the total generation of entropy (destruction of exergy). Various assumptions and constraints were considered and discussed. The total entropy generation rate and irreversibilities were determined by considering the individual components and ducts of the system, as well as their respective inlet and outlet conditions. The major system parameters were evaluated as functions of the mass flow rate to allow for a proper discussion of the system performance. The performances of both systems were investigated, and characteristics were listed for both. Finally, a comparison is made to shed light on the differences in performance. - Highlights: • Implementation of the second law of thermodynamics. • Design of heat exchanging and collecting equipment. • Utilisation of Entropy Generation Minimization. • Presentation of a multi-objective optimization. • Raise efficiency with more regeneration

  7. High-intensity cycle interval training improves cycling and running performance in triathletes.

    Science.gov (United States)

    Etxebarria, Naroa; Anson, Judith M; Pyne, David B; Ferguson, Richard A

    2014-01-01

    Effective cycle training for triathlon is a challenge for coaches. We compared the effects of two variants of cycle high-intensity interval training (HIT) on triathlon-specific cycling and running. Fourteen moderately-trained male triathletes ([Formula: see text]O2peak 58.7 ± 8.1 mL kg(-1) min(-1); mean ± SD) completed on separate occasions a maximal incremental test ([Formula: see text]O2peak and maximal aerobic power), 16 × 20 s cycle sprints and a 1-h triathlon-specific cycle followed immediately by a 5 km run time trial. Participants were then pair-matched and assigned randomly to either a long high-intensity interval training (LONG) (6-8 × 5 min efforts) or short high-intensity interval training (SHORT) (9-11 × 10, 20 and 40 s efforts) HIT cycle training intervention. Six training sessions were completed over 3 weeks before participants repeated the baseline testing. Both groups had an ∼7% increase in [Formula: see text]O2peak (SHORT 7.3%, ±4.6%; mean, ±90% confidence limits; LONG 7.5%, ±1.7%). There was a moderate improvement in mean power for both the SHORT (10.3%, ±4.4%) and LONG (10.7%, ±6.8%) groups during the last eight 20-s sprints. There was a small to moderate decrease in heart rate, blood lactate and perceived exertion in both groups during the 1-h triathlon-specific cycling but only the LONG group had a substantial decrease in the subsequent 5-km run time (64, ±59 s). Moderately-trained triathletes should use both short and long high-intensity intervals to improve cycling physiology and performance. Longer 5-min intervals on the bike are more likely to benefit 5 km running performance.

  8. Economic intermittency in a two-country model of business cycles coupled by investment

    Energy Technology Data Exchange (ETDEWEB)

    Saiki, Y., E-mail: saiki@math.sci.hokudai.ac.jp [Department of Mathematics, Hokkaido University, Sapporo 060-0810 (Japan); Chian, A.C.L. [National Institute for Space Research (INPE) and World Institute for Space Environment Research (WISER), P.O. Box 515, Sao Jose dos Campos-SP 12227-010 (Brazil); California Institute of Technology, Pasadena, CA 91125 (United States); Yoshida, H. [College of Economics, Nihon University, Tokyo 101-8360 (Japan)

    2011-06-15

    Highlights: > Intermittent economic behavior of Keynes-Goodwin type model is investigated. > After a transition the system keeps its memory before the transition. > The intermittent phenomena is examined from the business cycle patterns. > It is concluded that dynamical patterns do not alter much around the transition. - Abstract: Intermittent behavior of economic dynamics is investigated by a two-country model of Keynes-Goodwin type business cycles. Numerical simulations show that after an economic system evolves from weak chaos to strong chaos the system keeps its memory before the transition and its time series alternates episodically between periods of weakly and strongly chaotic fluctuations. In addition, we examine the intermittent phenomena from the view point of business cycle patterns near the crisis point.

  9. Economic intermittency in a two-country model of business cycles coupled by investment

    International Nuclear Information System (INIS)

    Saiki, Y.; Chian, A.C.L.; Yoshida, H.

    2011-01-01

    Highlights: → Intermittent economic behavior of Keynes-Goodwin type model is investigated. → After a transition the system keeps its memory before the transition. → The intermittent phenomena is examined from the business cycle patterns. → It is concluded that dynamical patterns do not alter much around the transition. - Abstract: Intermittent behavior of economic dynamics is investigated by a two-country model of Keynes-Goodwin type business cycles. Numerical simulations show that after an economic system evolves from weak chaos to strong chaos the system keeps its memory before the transition and its time series alternates episodically between periods of weakly and strongly chaotic fluctuations. In addition, we examine the intermittent phenomena from the view point of business cycle patterns near the crisis point.

  10. Proposal of a nuclear cycle research and development plan in Tokai works. The roadmap from LWR cycle to FBR cycle

    International Nuclear Information System (INIS)

    Nakamura, Hirofumi; Abe, Tomoyuki; Kashimura, Takuo; Nagai, Toshihisa; Maeda, Seichiro; Yamaguchi, Toshiya; Kuroki, Ryoichiro

    2003-07-01

    The Generation-II Project Task Force Team has investigated a research and development plan of a future nuclear fuel cycle in Tokai works for about three months from December 19, 2002. First we have discussed about the present condition of Japanese nuclear fuel cycle and have recognized it as the following. The relation of the technology between the LWR-cycle and the FBR-cycle is not clear. MOX Fuel Use in Light Water Reactors is important to establish technology of the FBR fuel cycle. Radioactive waste disposal issue is urgent. Next we have proposed the three basic policies on R and D plan of nuclear fuel cycle in consideration of the F.S. on FBR-cycle. Establishment and advancement of 'the tough nuclear fuel cycle'. Early establishment of the FBR cycle technology to be able to supply energy stably for long-term. Establishment of the radioactive waste treatment and disposal technology, and optimization of nuclear fuel cycle technology from the viewpoint of radioactive waste. And we have proposed the Japanese technical holder system to integrate all LWR and FBR cycle technology. (author)

  11. The control system of the ecological hybrid two stages refrigerating cycle

    Directory of Open Access Journals (Sweden)

    Cyklis Piotr

    2016-01-01

    Full Text Available The compression anticlockwise cycle is mostly used for refrigeration. However due to the environmental regulations, the use of classic refrigerants: F-gases is limited by international agreements. Therefore the combined compression-adsorption hybrid cycle with natural liquids: water/carbon dioxide working as the energy carriers is a promising solution. This allows to utilize the solar or waste energy for the refrigeration purpose. In this paper application of the solar collectors as the energy source for the adsorption cycle, coupled with the low temperature (LT refrigerating carbon dioxide compression cycle is shown. The control of the system is an essential issue to reduce the electric power consumption. The control of the solar heat supply and water sprayed cooling tower, for the adsorption cycle re-cooling, is presented in this paper. The designed control system and algorithm is related to the LT compression cycle, which operates according to the need of cold for the refrigeration chamber. The results of the laboratory investigations of the full system, showing the reduction of the energy consumption and maximum utilization of the solar heat for different control methods are presented.

  12. Simulation of Cycle-to-Cycle Variation in Dual-Fuel Engines

    KAUST Repository

    Jaasim, Mohammed

    2017-03-13

    Standard practices of internal combustion (IC) engine experiments are to conduct the measurements of quantities averaged over a large number of cycles. Depending on the operating conditions, the cycle-to-cycle variation (CCV) of quantities, such as the indicated mean effective pressure (IMEP) are observed at different levels. Accurate prediction of CCV in IC engines is an important but challenging task. Computational fluid dynamics (CFD) simulations using high performance computing (HPC) can be used effectively to visualize such 3D spatial distributions. In the present study, a dual fuel large engine is considered, with natural gas injected into the manifold accompanied with direct injection of diesel pilot fuel to trigger ignition. Multiple engine cycles in 3D are simulated in series as in the experiments to investigate the potential of HPC based high fidelity simulations to accurately capture the cycle to cycle variation in dual fuel engines. Open cycle simulations are conducted to predict the combined effect of the stratification of fuel-air mixture, temperature and turbulence on the CCV of pressure. The predicted coefficient of variation (COV) of pressure compared to the results from closed cycle simulations and the experiments.

  13. Glucose and fructose 6-phosphate cycle in humans

    International Nuclear Information System (INIS)

    Karlander, S.; Roovete, A.; Vranic, M.; Efendic, S.

    1986-01-01

    We have determined the rate of glucose cycling by comparing turnovers of [2- 3 H]- and [6- 3 H]glucose under basal conditions and during a glucose infusion. Moreover, the activity of the fructose 6-phosphate cycle was assessed by comparing [3- 3 H]- and [6- 3 H]glucose. The study included eight lean subjects with normal glucose tolerance. They participated in two randomly performed investigations. In one experiment [2- 3 H]- and [6- 3 H]glucose were given simultaneously, while in the other only [3- 3 H]glucose was given. The basal rate of glucose cycling was 0.32 +/- 0.08 mg X kg-1 X min-1 or 17% of basal glucose production (P less than 0.005). During glucose infusion the activity of endogenous glucose cycling did not change but since glucose production was suppressed it amounted to 130% of glucose production. The basal fructose 6-phosphate cycle could be detected only in three subjects and was suppressed during glucose infusion. In conclusion, the glucose cycle is active in healthy humans both in basal conditions and during moderate hyperglycemia. In some subjects, the fructose 6-phosphate cycle also appears to be active. Thus it is preferable to use [6- 3 H]glucose rather than [3- 3 H]glucose when measuring glucose production and particularly when assessing glucose cycle

  14. Fuel cycle centers revisited: Consolidation of fuel cycle activities in a few countries

    International Nuclear Information System (INIS)

    Kratzer, M.B.

    1996-01-01

    Despite varied expressions, the general impression remains that the international fuel cycle center concept, whatever its merits, is visionary. It also is quite possibly unattainable in light of strong national pressures toward independence and self-sufficiency in all things nuclear. Is the fuel cycle center an idea that has come and gone? Is it an idea whose time has not yet come? Or is it, as this paper suggests, an idea that has already arrived on the scene, attracting little attention or even acknowledgement of its presence? The difficult in answering this questions arises, in part, from the fact that despite its long and obvious appeal, there has been very little systematic analysis of the concept itself. Such obvious questions as how many and where fuel cycle centers should be located; what characteristics should the hot country or countries possess; and what are the institutional forms or features that endow the concept with enhanced proliferation protection have rarely been seriously and systematically addressed. The title of this paper focuses on limiting the geographic spread of fuel cycle facilities, and some may suggest that doing so does not necessarily call for any type of international or multinational arrangements applicable to those that exist. It is a premise of this paper, however, that a restriction on the number of countries possessing sensitive fuel cycle facilities necessarily involves some degree of multinationalization. This is not only because in every instance a nonproliferation pledge and international or multinational safeguards, or both, will be applied to the facility, but also because a restriction on the number of countries possessing these facilities implies that those in existence will serve a multinational market. This feature in itself is an important form of international auspices. Thus, the two concepts--limitation and multinationalization--if not necessarily one and the same, are at least de facto corollaries

  15. Nature's third cycle a story of sunspots

    CERN Document Server

    Choudhuri, Arnab Rai

    2015-01-01

    The cycle of day and night and the cycle of seasons are two familiar natural cycles around which many human activities are organized. But is there a third natural cycle of importance for us humans? On 13 March 1989, six million people in Canada went without electricity for many hours: a large explosion on the sun was discovered as the cause of this blackout. Such explosions occur above sunspots, dark features on the surface of the Sun that have been observed through telescopes since the time of Galileo. The number of sunspots has been found to wax and wane over a period of 11 years. Although this cycle was discovered less than two centuries ago, it is becoming increasingly important for us as human society becomes more dependent on technology. For nearly a century after its discovery, the cause of the sunspot cycle remained completely shrouded in mystery. The 1908 discovery of strong magnetic fields in sunspots made it clear that the 11-year cycle is the magnetic cycle of the sun. It is only during the last ...

  16. Poor response cycles: when should we cancel? Comparison of outcome between egg collection, intrauterine insemination conversion, and follow-up cycles after abandonment.

    Science.gov (United States)

    Nicopoullos, James D M; Abdalla, Hossam

    2011-01-01

    To determine optimal management with one or two mature follicles after stimulation. Retrospective analysis. Lister fertility clinic. A total of 1,350 IVF/intracytoplasmic sperm injection cycles (7.3% of total) during 1998-2009 were found to have one or two mature follicles. Group 1 (n = 807) comprised those who proceeded to vaginal egg collection (VEC) (59.8%; outcome per egg collection), group 2 (n=248) those who converted to IUI (18.4%; outcome per insemination) and group 3 (n=259) those who abandoned the current cycle (21.9%; outcome per abandoned cycle in first subsequent cycle). Live birth rate, clinical pregnancy rate, and biochemical pregnancy rate. Biochemical pregnancy rates of 13.1%, 4.9%, and 9.7%, clinical pregnancy rates of 8.1%, 3.6%, and 7.2%, and ongoing pregnancy rates of 6.8%, 2.0%, and 5.5% were achieved in groups 1, 2, and 3, respectively. All pregnancy outcomes were significantly higher after VEC (group 1) than for those converted to IUI (group 2), and all pregnancy outcomes were higher with borderline significance in group 3 vs. group 2. There was no significant difference in outcome between groups 1 and 3. Our data suggest that for such poor responders, proceeding to VEC may represent their best chance of successful outcome. Conversion to IUI offers the poorest outcome, and despite the potential for improvements in cycle protocol, abandoning and a further attempt does not improve outcome (using abandoned cycle as the denominator). Copyright © 2011 American Society for Reproductive Medicine. Published by Elsevier Inc. All rights reserved.

  17. Simulation of Cycle-to-Cycle Variation in Dual-Fuel Engines

    KAUST Repository

    Jaasim, Mohammed; Pasunurthi, Shyamsundar; Jupudi, Ravichandra S.; Gubba, Sreenivasa Rao; Primus, Roy; Klingbeil, Adam; Wijeyakulasuriya, Sameera; Im, Hong G.

    2017-01-01

    Standard practices of internal combustion (IC) engine experiments are to conduct the measurements of quantities averaged over a large number of cycles. Depending on the operating conditions, the cycle-to-cycle variation (CCV) of quantities

  18. The Sphinx's Riddle: Life and Career Cycles.

    Science.gov (United States)

    Burack, Elmer H.

    1984-01-01

    Career cycles should be considered apart from life cycles, even though the two are interrelated. This essay examines five theories about life and career cycles, and offers insights into their limitations and potential uses. (JB)

  19. Energy balance calculations and assessment of two thermochemical sulfur cycles

    International Nuclear Information System (INIS)

    Leger, D.; Lessart, P.; Manaud, J.P.; Benizri, R.; Courvoisier, P.

    1978-01-01

    Thermochemical cyclic processes which include the highly endothermal decomposition of sulphuric acid are promising for hydrogen production by water-splitting. Our study is directed toward two cycles of this family, each involving the formation and decomposition of sulphuric acid and including other reactions using iron sulphide for the first and oxides and bromides of copper and magnesium for the second. Thermochemical analyses of the two cycles are undertaken. Thermodynamic studies of the reactions are carried out, taking into account possible side-reactions. The concentration of reactants, products and by-products resulting from simultaneous equilibria are calculated, the problems of separation thoroughly studied and the flow-diagrams of the processes drawn up. Using as heat source the helium leaving a 3000 MWth high temperature nuclear reactor and organizing internal heat exchange the enthalpy diagrams are drawn up and the net energy balances evaluated. The overall thermal efficiencies are about 28%, a value corresponding to non-optimized process schemes. Possible improvements aiming at energy-saving and increased efficiency are indicated

  20. Life-cycle cost analysis of adsorption cycles for desalination

    KAUST Repository

    Thu, Kyaw

    2010-08-01

    This paper presents the thermo-economic analysis of the adsorption desalination (AD) cycle that is driven by low-temperature waste heat from exhaust of industrial processes or renewable sources. The AD cycle uses an adsorbent such as the silica gel to desalt the sea or brackish water. Based on an experimental prototype AD plant, the life-cycle cost analysis of AD plants of assorted water production capacities has been simulated and these predictions are translated into unit cost of water production. Our results show that the specific energy consumption of the AD cycle is 1.38 kWh/m3 which is the lowest ever reported. For a plant capacity of 1000 m3/d, the AD cycle offers a unit cost of $0.457/m3 as compared to more than $0.9 for the average RO plants. Besides being cost-effective, the AD cycle is also environment-friendly as it emits less CO2 emission per m3 generated, typically 85% less, by comparison to an RO process. © 2010 Desalination Publications.

  1. Dynamic simulation of natural convection bypass two-circuit cycle refrigerator-freezer and its application Part I: Component models

    International Nuclear Information System (INIS)

    Ding Guoliang; Zhang Chunlu; Lu Zhili

    2004-01-01

    In order to reduce the greenhouse gas emissions, efficient household refrigerator/freezers (RFs) are required. Bypass two-circuit cycle RFs with one compressor are proved to be more efficient than two-evaporator in series cycle RFs. In order to study the characteristics and improve the design of bypass two-circuit cycle RFs, a dynamic model is developed in this paper. In part I, the mathematic models of all components are presented, considering not only the accuracy of the models but also the computation stability and speed to solve the models. An efficiency model that requires a single calorimeter data point at the standard test condition is employed for compressor. A multi-zone model is employed for condenser and for evaporator, with its wall thermal capacity considered by effective metal method. The approximate integral analytic model is employed for adiabatic capillary tube, and the effective inlet enthalpy method is used to transfer the non-adiabatic capillary tube to adiabatic capillary tube. The z-transfer function model is employed for cabinet load calculation

  2. A reverse KREBS cycle in photosynthesis: consensus at last

    Science.gov (United States)

    Buchanan, B. B.; Arnon, D. I.

    1990-01-01

    The Krebs cycle (citric acid or tricarboxylic acid cycle), the final common pathway in aerobic metabolism for the oxidation of carbohydrates, fatty acids and amino acids, is known to be irreversible. It liberates CO2 and generates NADH whose aerobic oxidation yields ATP but it does not operate in reverse as a biosynthetic pathway for CO2 assimilation. In 1966, our laboratory described a cyclic pathway for CO2 assimilation (Evans, Buchanan and Arnon 1966) that was unusual in two respects: (i) it provided the first instance of an obligate photoautotroph that assimilated CO2 by a pathway different from Calvin's reductive pentose phosphate cycle (Calvin 1962) and (ii) in its overall effect the new cycle was a reversal of the Krebs cycle. Named the 'reductive carboxylic acid cycle' (sometimes also called the reductive tricarboxylic acid cycle) the new cycle appeared to be the sole CO2 assimilation pathway in Chlorobium thiosulfatophilum (Evans et al. 1966) (now known as Chlorobium limicola forma thiosulfatophilum). Chlorobium is a photosynthetic green sulfur bacterium that grows anaerobically in an inorganic medium with sulfide and thiosulfate as electron donors and CO2 as an obligatory carbon source. In the ensuing years, the new cycle was viewed with skepticism. Not only was it in conflict with the prevailing doctrine that the 'one important property ... shared by all (our emphasis) autotrophic species is the assimilation of CO2 via the Calvin cycle' (McFadden 1973) but also some of its experimental underpinnings were challenged. It is only now that in the words of one of its early skeptics (Tabita 1988) 'a long and tortuous controversy' has ended with general acceptance of the reductive carboxylic acid cycle as a photosynthetic CO2 assimilation pathway distinct from the pentose cycle. (Henceforth, to minimize repetitiveness, the reductive pentose phosphate cycle will often be referred to as the pentose cycle and the reductive carboxylic acid cycle as the carboxylic

  3. Reliability and validity of four alternative definitions of rapid-cycling bipolar disorder.

    Science.gov (United States)

    Maj, M; Pirozzi, R; Formicola, A M; Tortorella, A

    1999-09-01

    This study tested the reliability and validity of four definitions of rapid cycling. Two trained psychiatrists, using the Schedule for Affective Disorders and Schizophrenia, independently assessed 210 patients with bipolar disorder. They checked whether each patient met four definitions of rapid cycling: one consistent with DSM-IV criteria, one waiving criteria for duration of affective episodes, one waiving such criteria and requiring at least one switch from mania to depression or vice versa during the reference year, and one waiving duration criteria and requiring at least 8 weeks of fully symptomatic affective illness during the reference year. The interrater reliability was calculated by Cohen's kappa statistic. Patients who met each definition according to both psychiatrists were compared to those who did not meet any definition (nonrapid-cycling group) on demographic and clinical variables. All patients were followed up for 1 year. Kappa values were 0.93, 0.73, 0.75, and 0.80, respectively, for the four definitions of rapid cycling. The groups meeting the second and third definitions included significantly more female and bipolar II patients than did the nonrapid-cycling group. Those two groups also had the lowest proportion of patients with a favorable lithium prophylaxis outcome and the highest stability of the rapid-cycling pattern on follow-up. The four groups of rapid-cycling patients did not differ significantly among themselves on any of the assessed variables. The expression "rapid cycling" encompasses a spectrum of conditions. The DSM-IV definition, although quite reliable, covers only part of this spectrum, and the conditions that are excluded are very typical in terms of key validators and are relatively stable over time.

  4. Shaping of few-cycle laser pulses via a subwavelength structure

    International Nuclear Information System (INIS)

    Guo Liang; Xie Xiao-Tao; Zhan Zhi-Ming

    2013-01-01

    We theoretically investigate the propagation of few-cycle laser pulses in resonant two-level dense media with a subwavelength structure, which is described by the full Maxwell—Bloch equations without the frame of slowly varying envelope and rotating wave approximations. The input pulses can be shaped into shorter ones with a single or less than one optical cycle. The effect of the parameters of the subwavelength structure and laser pulses is studied. Our study shows that the media with a subwavelength structure can significantly shape the few-cycle pulses into a subcycle pulse, even for the case of chirp pulses as input fields. This suggests that such subwavelength structures have potential application in the shaping of few-cycle laser pulses. (electromagnetism, optics, acoustics, heat transfer, classical mechanics, and fluid dynamics)

  5. How well can business cycle accounting account for business cycles?

    OpenAIRE

    Keisuke Otsu

    2012-01-01

    The business cycle accounting method introduced by Chari, Kehoe and McGrattan (2007) is a useful tool to decompose business cycle fluctuations into their contributing factors. However, the model estimated by the maximum likelihood method cannot replicate business cycle moments computed from data. Moment-based estimation might be an attractive alternative if the purpose of the research is to study business cycle properties such as volatility, persistence and cross-correlation of variables inst...

  6. Measuring business cycles in The Netherlands, 1815-1913: a comparison of business cycle dating methods

    OpenAIRE

    Bonenkamp, Jan; Jacobs, Jan; Kuper, Gerard H.

    2001-01-01

    This paper compares different business cycle dating methods both on theoretical and practical grounds. Weighing the pros and cons of these methods, and based on a new data set for The Netherlands in the nineteenth century, we finally recommend two preferred methods for doing further business cycle research on the economy of the Netherlands. With respect to the methods for finding turning points in the level of economic activity, the classical cycle definition, we prefer the Bry-Boschan algori...

  7. Theory of limit cycles

    CERN Document Server

    Ye, Yan-Qian; Lo, Chi Y

    1986-01-01

    Over the past two decades the theory of limit cycles, especially for quadratic differential systems, has progressed dramatically in China as well as in other countries. This monograph, updating the 1964 first edition, includes these recent developments, as revised by eight of the author's colleagues in their own areas of expertise. The first part of the book deals with limit cycles of general plane stationary systems, including their existence, nonexistence, stability, and uniqueness. The second section discusses the global topological structure of limit cycles and phase-portraits of quadratic systems. Finally, the last section collects important results that could not be included under the subject matter of the previous two sections or that have appeared in the literature very recently. The book as a whole serves as a reference for college seniors, graduate students, and researchers in mathematics and physics.

  8. Quadratic reactivity fuel cycle model

    International Nuclear Information System (INIS)

    Lewins, J.D.

    1985-01-01

    For educational purposes it is highly desirable to provide simple yet realistic models for fuel cycle and fuel economy. In particular, a lumped model without recourse to detailed spatial calculations would be very helpful in providing the student with a proper understanding of the purposes of fuel cycle calculations. A teaching model for fuel cycle studies based on a lumped model assuming the summability of partial reactivities with a linear dependence of reactivity usefully illustrates fuel utilization concepts. The linear burnup model does not satisfactorily represent natural enrichment reactors. A better model, showing the trend of initial plutonium production before subsequent fuel burnup and fission product generation, is a quadratic fit. The study of M-batch cycles, reloading 1/Mth of the core at end of cycle, is now complicated by nonlinear equations. A complete account of the asymptotic cycle for any order of M-batch refueling can be given and compared with the linear model. A complete account of the transient cycle can be obtained readily in the two-batch model and this exact solution would be useful in verifying numerical marching models. It is convenient to treat the parabolic fit rho = 1 - tau 2 as a special case of the general quadratic fit rho = 1 - C/sub tau/ - (1 - C)tau 2 in suitably normalized reactivity and cycle time units. The parabolic results are given in this paper

  9. Do donor oocyte cycles comply with ASRM/SART embryo transfer guidelines? An analysis of 13,393 donor cycles from the SART registry.

    Science.gov (United States)

    Acharya, Kelly S; Keyhan, Sanaz; Acharya, Chaitanya R; Yeh, Jason S; Provost, Meredith P; Goldfarb, James M; Muasher, Suheil J

    2016-09-01

    To analyze donor oocyte cycles in the Society for Assisted Reproductive Technology (SART) registry to determine: 1) how many cycles complied with the 2009 American Society for Reproductive Medicine/SART embryo transfer guidelines; and 2) cycle outcomes according to the number of embryos transferred. For donor oocyte IVF with donor age cycles from 2011 to 2012. Embryos transferred in donor IVF cycles. Percentage of compliant cycles, multiple pregnancy rate. There were 3,157 donor cleavage-stage transfers and 10,236 donor blastocyst transfers. In the cleavage-stage cycles, 88% met compliance criteria. The multiple pregnancy rate (MPR) was significantly higher in the noncompliant cycles. In a subanalysis of compliant cleavage-stage cycles, 91% transferred two embryos and only 9% single embryos. In those patients transferring two embryos, the MPR was significantly higher (33% vs. 1%). In blastocyst transfers, only 28% of the cycles met compliance criteria. The MPR was significantly higher in the noncompliant blastocyst cohort at 53% (compared with 2% in compliant cycles). The majority of donor cleavage-stage transfers are compliant with current guidelines, but the transfer of two embryos results in a significantly higher MPR compared with single-embryo transfer. The majority of donor blastocyst cycles are noncompliant, which appears to be driving an unacceptably high MPR in these cycles. Copyright © 2016 American Society for Reproductive Medicine. Published by Elsevier Inc. All rights reserved.

  10. Validation of a mathematical model of the bovine estrous cycle for cows with different estrous cycle characteristics.

    Science.gov (United States)

    Boer, H M T; Butler, S T; Stötzel, C; Te Pas, M F W; Veerkamp, R F; Woelders, H

    2017-11-01

    A recently developed mechanistic mathematical model of the bovine estrous cycle was parameterized to fit empirical data sets collected during one estrous cycle of 31 individual cows, with the main objective to further validate the model. The a priori criteria for validation were (1) the resulting model can simulate the measured data correctly (i.e. goodness of fit), and (2) this is achieved without needing extreme, probably non-physiological parameter values. We used a least squares optimization procedure to identify parameter configurations for the mathematical model to fit the empirical in vivo measurements of follicle and corpus luteum sizes, and the plasma concentrations of progesterone, estradiol, FSH and LH for each cow. The model was capable of accommodating normal variation in estrous cycle characteristics of individual cows. With the parameter sets estimated for the individual cows, the model behavior changed for 21 cows, with improved fit of the simulated output curves for 18 of these 21 cows. Moreover, the number of follicular waves was predicted correctly for 18 of the 25 two-wave and three-wave cows, without extreme parameter value changes. Estimation of specific parameters confirmed results of previous model simulations indicating that parameters involved in luteolytic signaling are very important for regulation of general estrous cycle characteristics, and are likely responsible for differences in estrous cycle characteristics between cows.

  11. Cycling in Sydney, Australia

    Directory of Open Access Journals (Sweden)

    Alexis Zander

    2013-01-01

    Full Text Available Introduction. Cycling can be an enjoyable way to meet physical activity recommendations and is suitable for older people; however cycling participation by older Australians is low. This qualitative study explored motivators, enablers, and barriers to cycling among older people through an age-targeted cycling promotion program. Methods. Seventeen adults who aged 50–75 years participated in a 12-week cycling promotion program which included a cycling skills course, mentor, and resource pack. Semistructured interviews at the beginning and end of the program explored motivators, enablers, and barriers to cycling. Results. Fitness and recreation were the primary motivators for cycling. The biggest barrier was fear of cars and traffic, and the cycling skills course was the most important enabler for improving participants’ confidence. Reported outcomes from cycling included improved quality of life (better mental health, social benefit, and empowerment and improved physical health. Conclusions. A simple cycling program increased cycling participation among older people. This work confirms the importance of improving confidence in this age group through a skills course, mentors, and maps and highlights additional strategies for promoting cycling, such as ongoing improvement to infrastructure and advertising.

  12. Fuel cycle related parametric study considering long lived actinide production, decay heat and fuel cycle performances

    International Nuclear Information System (INIS)

    Raepsaet, X.; Damian, F.; Lenain, R.; Lecomte, M.

    2001-01-01

    One of the very attractive HTGR reactor characteristics is its highly versatile and flexible core that can fulfil a wide range of diverse fuel cycles. Based on a GTMHR-600 MWth reactor, analyses of several fuel cycles were carried out without taking into account common fuel particle performance limits (burnup, fast fluence, temperature). These values are, however, indicated in each case. Fuel derived from uranium, thorium and a wide variety of plutonium grades has been considered. Long-lived actinide production and total residual decay heat were evaluated for the various types of fuel. The results presented in this papers provide a comparison of the potential and limits of each fuel cycle and allow to define specific cycles offering lowest actinide production and residual heat associated with a long life cycle. (author)

  13. The Effects of One and Double Heat Treatment Cycles on the Microstructure and Mechanical Properties of a Ferritic-Bainitic Dual Phase Steel

    Science.gov (United States)

    Piri, Reza; Ghasemi, Behrooz; Yousefpour, Mardali

    2018-03-01

    In this study, samples with ferritic-bainitic dual phase structures consisting of 62 pct bainite were obtained from the AISI 4140 steel by applying one and double heat treatment cycles. Microstructural investigations by electron and optical microscopy indicated that the sample heat treated through double cycle benefited from finer ferrite and bainite grains. Additionally, results obtained from mechanical tests implied that the double-cycle heat-treated sample not only has a higher tensile strength as well as ultimate strength but also benefits from a higher ductility along with a higher impact energy than the one-cycle heat-treated sample. Moreover, fractography results showed that the type of fracture in both samples is a combination of the brittle and the ductile fracture. Besides, the ratio of the ductile fracture is higher for the double-cycle heat-treated sample than for the one-cycle sample, due to the lower aggregation of sulfur at grain boundaries.

  14. Marine nitrogen cycle

    Digital Repository Service at National Institute of Oceanography (India)

    Naqvi, S.W.A.

    ) such as the Marine nitrogen cycle The marine nitrogen cycle. ‘X’ and ‘Y’ are intra-cellular intermediates that do not accumulate in water column. (Source: Codispoti et al., 2001) Page 1 of 3Marine nitrogen cycle - Encyclopedia of Earth 11/20/2006http://www... and nitrous oxide budgets: Moving targets as we enter the anthropocene?, Sci. Mar., 65, 85-105, 2001. Page 2 of 3Marine nitrogen cycle - Encyclopedia of Earth 11/20/2006http://www.eoearth.org/article/Marine_nitrogen_cycle square6 Gruber, N.: The dynamics...

  15. Hamiltonian cycles in polyhedral maps

    Indian Academy of Sciences (India)

    We present a necessary and sufficient condition for existence of a contractible, non-separating and non-contractible separating Hamiltonian cycle in the edge graph of polyhedral maps on surfaces.We also present algorithms to construct such cycles whenever it exists where one of them is linear time and another is ...

  16. HTGR fuel and fuel cycle technology

    International Nuclear Information System (INIS)

    Lotts, A.L.; Homan, F.J.; Balthesen, E.; Turner, R.F.

    1977-01-01

    Significant advances have occurred in the development of HTGR fuel and fuel cycle. These accomplishments permit a wide choice of fuel designs, reactor concepts, and fuel cycles. Fuels capable of providing helium outlet temperatures of 750 0 C are available, and fuels capable of 1000 0 C outlet temperatures may be expected from extension of present technology. Fuels have been developed for two basic HTGR designs, one using a spherical (pebble bed) element and the other a prismatic element. Within each concept a number of variations of geometry, fuel composition, and structural materials are permitted. Potential fuel cycles include both low-enriched and high-enriched Th- 235 U, recycle Th- 233 U, and Th-Pu or U-Pu cycles. This flexibility offered by the HTGR is of great practical benefit considering the rapidly changing economics of power production. The inflation of ore prices has increased optimum conversion ratios, and increased the necessity of fuel recycle at an early date. Fuel element makeup is very similar for prismatic and spherical designs. Both use spherical fissile and fertile particles coated with combinations of pyrolytic carbon and silicon carbide. Both use carbonaceous binder materials, and graphite as the structural material. Weak-acid resin (WAR) UO 2 -UC 2 fissile fuels and sol-gel-derived ThO 2 fertile fuels have been selected for the Th- 233 U cycle in the prismatic design. Sol-gel-derived UO 2 UC 2 is the reference fissile fuel for the low-enriched pebble bed design. Both the United States and Federal Republic of Germany are developing technology for fuel cycle operations including fabrication, reprocessing, refabrication, and waste handling. Feasibility of basic processes has been established and designs developed for full-scale equipment. Fuel and fuel cycle technology provide the basis for a broad range of applications of the HTGR. Extension of the fuels to higher operating temperatures and development and commercial demonstration of fuel

  17. Estrus behavior, ovarian dynamics, and progesterone secretion in Criollo cattle during estrous cycles with two and three follicular waves.

    Science.gov (United States)

    Quezada-Casasola, Andrés; Avendaño-Reyes, Leonel; Macías-Cruz, Ulises; Ramírez-Godínez, José Alejandro; Correa-Calderón, Abelardo

    2014-04-01

    In beef and dairy cattle, the number of follicular waves affects endocrine, ovarian, and behavioral events during a normal estrous cycle. However, in Mexican-native Criollo cattle, a shortly and recently domesticated breed, the association between wave patterns and follicular development has not been studied. The objective of this study was to evaluate the effect of number of follicular waves in an estrous cycle on development of anovulatory and ovulatory follicles, corpus luteum (CL) development and functionality, as well as estrual behavior in Criollo cows. Ovarian follicular activities of 22 cycling multiparous Criollo cows were recorded daily by transrectal ultrasound examinations during a complete estrous cycle. Additionally, blood samples were collected daily to determine serum progesterone concentrations. Only two- (n = 17, 77.3%) and three-wave follicular (n = 5, 22.7%) patterns were observed. Duration of estrus, length of estrous cycle, and length of follicular and luteal phases were similar (P > 0.05) between cycles of two and three waves. Two-wave cows ovulated earlier (P 0.05) by number of waves. Growth rate of first dominant follicle was higher (P 0.05) between two- and three-wave patterns. In conclusion, Criollo cows have two or three follicular waves per estrous cycle, which alters partially ovulatory follicle development and ovulation time after detection of estrus. Length of estrous cycle, as well as CL development and functionality, was not affected by number of follicular waves.

  18. Comparative analysis of thermodynamic performance and optimization of organic flash cycle (OFC) and organic Rankine cycle (ORC)

    International Nuclear Information System (INIS)

    Lee, Ho Yong; Park, Sang Hee; Kim, Kyoung Hoon

    2016-01-01

    A comparative thermodynamic performance and optimization analysis of basic organic flash cycle (OFCB), organic flash cycle with two-phase expander (OFCT), and organic Rankine cycle (ORC) activated by low-temperature sensible energy is carried out in the subcritical pressure regions. The three substances of R245fa, R123, and o-xylene are considered as the working fluids. Effects of cycle type, working fluid, and evaporation and source temperatures are systemically investigated on the system performance such as net power production, thermal and exergy efficiencies, and exergy destruction ratios at each component of the systems. Results show that the cycle type or working fluid which shows optimum performance depends on the source temperature, and organic flash cycle shows a potential for efficient recovery of low grade energy source.

  19. Development and comparison of different advanced absorption cycles

    Energy Technology Data Exchange (ETDEWEB)

    Arh, S; Gaspersic, B [Faculty of Mechanical Engineering, Ljubjana (YU)

    1990-01-01

    A method for the calculation of the coefficient of performance for any absorption cycle is described. This method was used for the evaluation of different advanced absorption cycles working between four temperature and two or three pressure levels. Similar cycles were compared in the same temperature range with regard to the coefficient of performance, exergy efficiency and two working fluid pairs, NH{sub 3}-H{sub 2}O and H{sub 2}O-LiBr. Cycles and numerical results are presented and a computer-aided absorption cycle development system described. (author).

  20. Self-organizing maps based on limit cycle attractors.

    Science.gov (United States)

    Huang, Di-Wei; Gentili, Rodolphe J; Reggia, James A

    2015-03-01

    Recent efforts to develop large-scale brain and neurocognitive architectures have paid relatively little attention to the use of self-organizing maps (SOMs). Part of the reason for this is that most conventional SOMs use a static encoding representation: each input pattern or sequence is effectively represented as a fixed point activation pattern in the map layer, something that is inconsistent with the rhythmic oscillatory activity observed in the brain. Here we develop and study an alternative encoding scheme that instead uses sparsely-coded limit cycles to represent external input patterns/sequences. We establish conditions under which learned limit cycle representations arise reliably and dominate the dynamics in a SOM. These limit cycles tend to be relatively unique for different inputs, robust to perturbations, and fairly insensitive to timing. In spite of the continually changing activity in the map layer when a limit cycle representation is used, map formation continues to occur reliably. In a two-SOM architecture where each SOM represents a different sensory modality, we also show that after learning, limit cycles in one SOM can correctly evoke corresponding limit cycles in the other, and thus there is the potential for multi-SOM systems using limit cycles to work effectively as hetero-associative memories. While the results presented here are only first steps, they establish the viability of SOM models based on limit cycle activity patterns, and suggest that such models merit further study. Copyright © 2014 Elsevier Ltd. All rights reserved.

  1. Creeping of hysteresis cycles; Reptation des cycles d'hysteresis

    Energy Technology Data Exchange (ETDEWEB)

    Neel, L [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires; Faculte des Sciences de Grenoble, 38 (France)

    1959-07-01

    Creeping consists of a kind of progressive translation of dissymmetric ferromagnetic hysteresis cycles as a function of the order number of the cycle. It is interpreted here by means of a probable coupling field, the existence of which is connected to a statistical conception of the distribution of the elementary regions. (author) [French] La reptation consiste en une sorte de translation progressive des cycles d'hysteresis ferromagnetiques dissymetriques en fonction du numero d'ordre du cycle. L'auteur l'interprete au moyen d'un champ aleatoire de couplage dont l'existence est liee a une conception statistique de la distribution des domaines elementaires. (auteur)

  2. Numerical investigation into the existence of limit cycles in two-dimensional predator�prey systems

    Directory of Open Access Journals (Sweden)

    Quay van der Hoff

    2013-05-01

    Full Text Available There has been a surge of interest in developing and analysing models of interacting species in ecosystems, with specific interest in investigating the existence of limit cycles in systems describing the dynamics of these species. The original Lotka–Volterra model does not possess any limit cycles. In recent years this model has been modified to take disturbances into consideration and allow populations to return to their original numbers. By introducing logistic growth and a Holling Type II functional response to the traditional Lotka–Volterra-type models, it has been proven analytically that a unique, stable limit cycle exists. These proofs make use of Dulac functions, Liénard equations and invariant regions, relying on theory developed by Poincaré, Poincaré-Bendixson, Dulac and Liénard, and are generally perceived as difficult. Computer algebra systems are ideally suited to apply numerical methods to confirm or refute the analytical findings with respect to the existence of limit cycles in non-linear systems. In this paper a class of predator–prey models of a Gause type is used as the vehicle to illustrate the use of a simple, yet novel numerical algorithm. This algorithm confirms graphically the existence of at least one limit cycle that has analytically been proven to exist. Furthermore, adapted versions of the proposed algorithm may be applied to dynamic systems where it is difficult, if not impossible, to prove analytically the existence of limit cycles.

  3. Quantifying fluctuations in reversible enzymatic cycles and clocks

    Science.gov (United States)

    Wierenga, Harmen; ten Wolde, Pieter Rein; Becker, Nils B.

    2018-04-01

    Biochemical reactions are fundamentally noisy at a molecular scale. This limits the precision of reaction networks, but it also allows fluctuation measurements that may reveal the structure and dynamics of the underlying biochemical network. Here, we study nonequilibrium reaction cycles, such as the mechanochemical cycle of molecular motors, the phosphorylation cycle of circadian clock proteins, or the transition state cycle of enzymes. Fluctuations in such cycles may be measured using either of two classical definitions of the randomness parameter, which we show to be equivalent in general microscopically reversible cycles. We define a stochastic period for reversible cycles and present analytical solutions for its moments. Furthermore, we associate the two forms of the randomness parameter with the thermodynamic uncertainty relation, which sets limits on the timing precision of the cycle in terms of thermodynamic quantities. Our results should prove useful also for the study of temporal fluctuations in more general networks.

  4. Glacial cycles

    DEFF Research Database (Denmark)

    Kaufmann, R. K.; Juselius, Katarina

    We use a statistical model, the cointegrated vector autoregressive model, to assess the degree to which variations in Earth's orbit and endogenous climate dynamics can be used to simulate glacial cycles during the late Quaternary (390 kyr-present). To do so, we estimate models of varying complexity...... and compare the accuracy of their in-sample simulations. Results indicate that strong statistical associations between endogenous climate variables are not enough for statistical models to reproduce glacial cycles. Rather, changes in solar insolation associated with changes in Earth's orbit are needed...... to simulate glacial cycles accurately. Also, results suggest that non-linear 10 dynamics, threshold effects, and/or free oscillations may not play an overriding role in glacial cycles....

  5. [Physiological differences between cycling and running].

    Science.gov (United States)

    Millet, Grégoire

    2009-08-05

    This review compares the differences in systemic responses (VO2max, anaerobic threshold, heart rate and economy) and in underlying mechanisms of adaptation (ventilatory and hemodynamic and neuromuscular responses) between cycling and running. VO2max is specific to the exercise modality. Overall, there is more physiological training transfer from running to cycling than vice-versa. Several other physiological differences between cycling and running are discussed: HR is different between the two activities both for maximal and sub-maximal intensities. The delta efficiency is higher in running. Ventilation is more impaired in cycling than running due to mechanical constraints. Central fatigue and decrease in maximal strength are more important after prolonged exercise in running than in cycling.

  6. Pyroelectric Energy Harvesting: With Thermodynamic-Based Cycles

    OpenAIRE

    Saber Mohammadi; Akram Khodayari

    2012-01-01

    This work deals with energy harvesting from temperature variations using ferroelectric materials as a microgenerator. The previous researches show that direct pyroelectric energy harvesting is not effective, whereas thermodynamic-based cycles give higher energy. Also, at different temperatures some thermodynamic cycles exhibit different behaviours. In this paper pyroelectric energy harvesting using Lenoir and Ericsson thermodynamic cycles has been studied numerically and the two cycles were c...

  7. Consistency of seven different GNSS global ionospheric mapping techniques during one solar cycle

    Science.gov (United States)

    Roma-Dollase, David; Hernández-Pajares, Manuel; Krankowski, Andrzej; Kotulak, Kacper; Ghoddousi-Fard, Reza; Yuan, Yunbin; Li, Zishen; Zhang, Hongping; Shi, Chuang; Wang, Cheng; Feltens, Joachim; Vergados, Panagiotis; Komjathy, Attila; Schaer, Stefan; García-Rigo, Alberto; Gómez-Cama, José M.

    2018-06-01

    In the context of the International GNSS Service (IGS), several IGS Ionosphere Associated Analysis Centers have developed different techniques to provide global ionospheric maps (GIMs) of vertical total electron content (VTEC) since 1998. In this paper we present a comparison of the performances of all the GIMs created in the frame of IGS. Indeed we compare the classical ones (for the ionospheric analysis centers CODE, ESA/ESOC, JPL and UPC) with the new ones (NRCAN, CAS, WHU). To assess the quality of them in fair and completely independent ways, two assessment methods are used: a direct comparison to altimeter data (VTEC-altimeter) and to the difference of slant total electron content (STEC) observed in independent ground reference stations (dSTEC-GPS). The main conclusion of this study, performed during one solar cycle, is the consistency of the results between so many different GIM techniques and implementations.

  8. The glutathione cycle: Glutathione metabolism beyond the γ-glutamyl cycle.

    Science.gov (United States)

    Bachhawat, Anand Kumar; Yadav, Shambhu

    2018-04-17

    Glutathione was discovered in 1888, over 125 years ago. Since then, our understanding of various functions and metabolism of this important molecule has grown over these years. But it is only now, in the last decade, that a somewhat complete picture of its metabolism has emerged. Glutathione metabolism has till now been largely depicted and understood by the γ-glutamyl cycle that was proposed in 1970. However, new findings and knowledge particularly on the transport and degradation of glutathione have revealed that many aspects of the γ-glutamyl cycle are incorrect. Despite this, an integrated critical analysis of the cycle has never been undertaken and this has led to the cycle and its errors perpetuating in the literature. This review takes a careful look at the γ-glutamyl cycle and its shortcomings and presents a "glutathione cycle" that captures the current understanding of glutathione metabolism. © 2018 IUBMB Life, 2018. © 2018 International Union of Biochemistry and Molecular Biology.

  9. [Cycling in Zagreb].

    Science.gov (United States)

    Matos, Stipan; Krapac, Ladislav; Krapac, Josip

    2007-01-01

    Cycling in Zagreb, as means of urban transport inside and outside the city, has a bright past, hazy presence but a promising future. Every day, aggressive citizens who lack urban traffic culture mistreat many cyclists but also many pedestrians. Sedentary way of living, unhealthy eating habits and inadequate recreation would surely be reduced if Zagreb had a network of cycling tracks (190 cm) or lanes (80 cm). Main city roads were constructed at the beginning of the 20th century. Today, the lack of cycling tracks is particularly evident in terms of missing connections between northern and southern parts of the city. Transportation of bikes in public vehicles, parking of bikes as well as cycling along the foot of the mountains Medvednica and Zumberacko gorje is not adequately organized. Better organization is necessary not only because of the present young generation but also because of the young who will shortly become citizens of the EU, where cycling is enormously popular. Cycling tourism is not known in Zagreb, partly due to inadequate roads. The surroundings of Zagreb are more suitable for cycling tourism and attractive brochures and tourist guides offer information to tourists on bikes. Professional, acrobatic and sports cycling do not have a tradition in Zagreb and in Croatia. The same holds true for recreational cycling and indoor exercise cycling. The authors discuss the impact of popularization of cycling using print and electronic media. The role of district and local self-government in the construction and improvement of traffic roads in Zagreb is very important. It is also significant for the implementation of legal regulations that must be obeyed by all traffic participants in order to protect cyclists, the most vulnerable group of traffic participants besides passengers. Multidisciplinary action of all benevolent experts would surely increase safety and pleasure of cycling in the city and its surroundings. This would also help reduce daily stress and

  10. Modeling transit bus fuel consumption on the basis of cycle properties.

    Science.gov (United States)

    Delgado, Oscar F; Clark, Nigel N; Thompson, Gregory J

    2011-04-01

    A method exists to predict heavy-duty vehicle fuel economy and emissions over an "unseen" cycle or during unseen on-road activity on the basis of fuel consumption and emissions data from measured chassis dynamometer test cycles and properties (statistical parameters) of those cycles. No regression is required for the method, which relies solely on the linear association of vehicle performance with cycle properties. This method has been advanced and examined using previously published heavy-duty truck data gathered using the West Virginia University heavy-duty chassis dynamometer with the trucks exercised over limited test cycles. In this study, data were available from a Washington Metropolitan Area Transit Authority emission testing program conducted in 2006. Chassis dynamometer data from two conventional diesel buses, two compressed natural gas buses, and one hybrid diesel bus were evaluated using an expanded driving cycle set of 16 or 17 different driving cycles. Cycle properties and vehicle fuel consumption measurements from three baseline cycles were selected to generate a linear model and then to predict unseen fuel consumption over the remaining 13 or 14 cycles. Average velocity, average positive acceleration, and number of stops per distance were found to be the desired cycle properties for use in the model. The methodology allowed for the prediction of fuel consumption with an average error of 8.5% from vehicles operating on a diverse set of chassis dynamometer cycles on the basis of relatively few experimental measurements. It was found that the data used for prediction should be acquired from a set that must include an idle cycle along with a relatively slow transient cycle and a relatively high speed cycle. The method was also applied to oxides of nitrogen prediction and was found to have less predictive capability than for fuel consumption with an average error of 20.4%.

  11. Advanced fuel cycles options for LWRs and IMF benchmark definition

    International Nuclear Information System (INIS)

    Breza, J.; Darilek, P.; Necas, V.

    2008-01-01

    In the paper, different advanced nuclear fuel cycles including thorium-based fuel and inert-matrix fuel are examined under light water reactor conditions, especially VVER-440, and compared. Two investigated thorium based fuels include one solely plutonium-thorium based fuel and the second one plutonium-thorium based fuel with initial uranium content. Both of them are used to carry and burn or transmute plutonium created in the classical UOX cycle. The inert-matrix fuel consist of plutonium and minor actinides separated from spent UOX fuel fixed in Yttria-stabilised zirconia matrix. The article shows analysed fuel cycles and their short description. The conclusion is concentrated on the rate of Pu transmutation and Pu with minor actinides cumulating in the spent advanced thorium fuel and its comparison to UOX open fuel cycle. Definition of IMF benchmark based on presented scenario is given. (authors)

  12. Limit cycles in quantum systems

    Energy Technology Data Exchange (ETDEWEB)

    Niemann, Patrick

    2015-04-27

    In this thesis we investigate Limit Cycles in Quantum Systems. Limit cycles are a renormalization group (RG) topology. When degrees of freedom are integrated out, the coupling constants flow periodically in a closed curve. The presence of limit cycles is restricted by the necessary condition of discrete scale invariance. A signature of discrete scale invariance and limit cycles is log-periodic behavior. The first part of this thesis is concerned with the study of limit cycles with the similarity renormalization group (SRG). Limit cycles are mainly investigated within conventional renormalization group frameworks, where degrees of freedom, which are larger than a given cutoff, are integrated out. In contrast, in the SRG potentials are unitarily transformed and thereby obtain a band-diagonal structure. The width of the band structure can be regarded as an effective cutoff. We investigate the appearance of limit cycles in the SRG evolution. Our aim is to extract signatures as well as the scaling factor of the limit cycle. We consider the 1/R{sup 2}-potential in a two-body system and a three-body system with large scattering lengths. Both systems display a limit cycle. Besides the frequently used kinetic energy generator we apply the exponential and the inverse generator. In the second part of this thesis, Limit Cycles at Finite Density, we examine the pole structure of the scattering amplitude for distinguishable fermions at zero temperature in the medium. Unequal masses and a filled Fermi sphere for each fermion species are considered. We focus on negative scattering lengths and the unitary limit. The properties of the three-body spectrum in the medium and implications for the phase structure of ultracold Fermi gases are discussed.

  13. Parametric-based thermodynamic analysis of organic Rankine cycle as bottoming cycle for combined-cycle power plant

    International Nuclear Information System (INIS)

    Qureshi, S.; Memon, A.G.; Abbasi, A.F.

    2017-01-01

    In Pakistan, the thermal efficiency of the power plants is low because of a huge share of fuel energy is dumped into the atmosphere as waste heat. The ORC (Organic Rankine Cycle) has been revealed as one of the promising technologies to recover waste heat to enhance the thermal efficiency of the power plant. In current work, ORC is proposed as a second bottoming cycle for existing CCPP (Combined Cycle Power Plant). In order to assess the efficiency of the plant, a thermodynamic model is developed in the ESS (Engineering Equation Solver) software. The developed model is used for parametric analysis to assess the effects of various operating parameters on the system performance. The analysis of results shows that the integration of ORC system with existing CCPP system enhances the overall power output in the range of 150.5-154.58 MW with 0.24-5% enhancement in the efficiency depending on the operating conditions. During the parametric analysis of ORC, it is observed that inlet pressure of the turbine shows a significant effect on the performance of the system as compared to other operating parameters. (author)

  14. BUSINESS CYCLES, ELECTORAL CYCLES. TOWARD A THEORETICAL FRAME OF INTERACTION

    Directory of Open Access Journals (Sweden)

    BOGDAN-LUCIAN DOSPINESCU

    2015-06-01

    Full Text Available The idea of cyclical movement of a system: be it political, economic, institutional, is one of the constants of critical thinking. In this sense, there is a natural cyclic movement that cannot be avoided (only amplified or diminished and is connected with the nature of these systems. The economy follows a cyclical movement; a period of growth follows a period of decline, and so on. So does popularity for political parties or leaders. In this paper, I explore the links between the business cycles and electoral cycles. For this purpose, I introduce the concept of electoral perception cycles. My hypothesis is that popularity of political parties and leaders follow a cyclical evolution, both on short and long term. I show how perception cycles can impact the “political business cycle theory”. There is great interest in political science literature for the factors that influence the fluctuations in Presidents’ popularity, especially from United States. However, very little has been said about Romania’s case. I investigate the hypothesis of electoral perception cycles looking at the popularity of former president Traian Basescu, over his two terms. The variable used to measure popularity is favorability, measured in national surveys, done face to face, on representative samplez, of around 1000 subjects. I’ve correlated the fluctuations in favorability over time, with key public events or political decisions taken by Traian Băsescu. The main findings are as follows. Firstly, there are significant short term fluctuations (short term perception cycles and they are correlated with major events on the agenda. I would point the following key moments: 1. The referendum for dismissal of the President in May 2007 – Traian Băsescu’s favorability increased by 7 percentage points; 2. The referendum for unicameral Parliament with 300 MPs in the fall of 2009. Coupled with victory in the presidential election, it lead to an increase of 10 percentage

  15. Internal cycle modeling and environmental assessment of multiple cycle consumer products

    International Nuclear Information System (INIS)

    Tsiliyannis, C.A.

    2012-01-01

    Highlights: ► Dynamic flow models are presented for remanufactured, reused or recycled products. ► Early loss and stochastic return are included for fast and slow cycling products. ► The reuse-to-input flow ratio (Internal Cycle Factor, ICF) is determined. ► The cycle rate, which is increasing with the ICF, monitors eco-performance. ► Early internal cycle losses diminish the ICF, the cycle rate and performance. - Abstract: Dynamic annual flow models incorporating consumer discard and usage loss and featuring deterministic and stochastic end-of-cycle (EOC) return by the consumer are developed for reused or remanufactured products (multiple cycle products, MCPs), including fast and slow cycling, short and long-lived products. It is shown that internal flows (reuse and overall consumption) increase proportionally to the dimensionless internal cycle factor (ICF) which is related to environmental impact reduction factors. The combined reuse/recycle (or cycle) rate is shown capable for shortcut, albeit effective, monitoring of environmental performance in terms of waste production, virgin material extraction and manufacturing impacts of all MCPs, a task, which physical variables (lifetime, cycling frequency, mean or total number of return trips) and conventional rates, via which environmental policy has been officially implemented (e.g. recycling rate) cannot accomplish. The cycle rate is shown to be an increasing (hyperbolic) function of ICF. The impact of the stochastic EOC return characteristics on total reuse and consumption flows, as well as on eco-performance, is assessed: symmetric EOC return has a small, positive effect on performance compared to deterministic, while early shifted EOC return is more beneficial. In order to be efficient, environmental policy should set higher minimum reuse targets for higher trippage MCPs. The results may serve for monitoring, flow accounting and comparative eco-assessment of MCPs. They may be useful in identifying

  16. Dynamic Simulations of Advanced Fuel Cycles

    International Nuclear Information System (INIS)

    Piet, Steven J.; Dixon, Brent W.; Jacobson, Jacob J.; Matthern, Gretchen E.; Shropshire, David E.

    2011-01-01

    Years of performing dynamic simulations of advanced nuclear fuel cycle options provide insights into how they could work and how one might transition from the current once-through fuel cycle. This paper summarizes those insights from the context of the 2005 objectives and goals of the U.S. Advanced Fuel Cycle Initiative (AFCI). Our intent is not to compare options, assess options versus those objectives and goals, nor recommend changes to those objectives and goals. Rather, we organize what we have learned from dynamic simulations in the context of the AFCI objectives for waste management, proliferation resistance, uranium utilization, and economics. Thus, we do not merely describe 'lessons learned' from dynamic simulations but attempt to answer the 'so what' question by using this context. The analyses have been performed using the Verifiable Fuel Cycle Simulation of Nuclear Fuel Cycle Dynamics (VISION). We observe that the 2005 objectives and goals do not address many of the inherently dynamic discriminators among advanced fuel cycle options and transitions thereof.

  17. Microarray labeling extension values: laboratory signatures for Affymetrix GeneChips

    Science.gov (United States)

    Lee, Yun-Shien; Chen, Chun-Houh; Tsai, Chi-Neu; Tsai, Chia-Lung; Chao, Angel; Wang, Tzu-Hao

    2009-01-01

    Interlaboratory comparison of microarray data, even when using the same platform, imposes several challenges to scientists. RNA quality, RNA labeling efficiency, hybridization procedures and data-mining tools can all contribute variations in each laboratory. In Affymetrix GeneChips, about 11–20 different 25-mer oligonucleotides are used to measure the level of each transcript. Here, we report that ‘labeling extension values (LEVs)’, which are correlation coefficients between probe intensities and probe positions, are highly correlated with the gene expression levels (GEVs) on eukayotic Affymetrix microarray data. By analyzing LEVs and GEVs in the publicly available 2414 cel files of 20 Affymetrix microarray types covering 13 species, we found that correlations between LEVs and GEVs only exist in eukaryotic RNAs, but not in prokaryotic ones. Surprisingly, Affymetrix results of the same specimens that were analyzed in different laboratories could be clearly differentiated only by LEVs, leading to the identification of ‘laboratory signatures’. In the examined dataset, GSE10797, filtering out high-LEV genes did not compromise the discovery of biological processes that are constructed by differentially expressed genes. In conclusion, LEVs provide a new filtering parameter for microarray analysis of gene expression and it may improve the inter- and intralaboratory comparability of Affymetrix GeneChips data. PMID:19295132

  18. Multiparameter Cell Cycle Analysis.

    Science.gov (United States)

    Jacobberger, James W; Sramkoski, R Michael; Stefan, Tammy; Woost, Philip G

    2018-01-01

    Cell cycle cytometry and analysis are essential tools for studying cells of model organisms and natural populations (e.g., bone marrow). Methods have not changed much for many years. The simplest and most common protocol is DNA content analysis, which is extensively published and reviewed. The next most common protocol, 5-bromo-2-deoxyuridine S phase labeling detected by specific antibodies, is also well published and reviewed. More recently, S phase labeling using 5'-ethynyl-2'-deoxyuridine incorporation and a chemical reaction to label substituted DNA has been established as a basic, reliable protocol. Multiple antibody labeling to detect epitopes on cell cycle regulated proteins, which is what this chapter is about, is the most complex of these cytometric cell cycle assays, requiring knowledge of the chemistry of fixation, the biochemistry of antibody-antigen reactions, and spectral compensation. However, because this knowledge is relatively well presented methodologically in many papers and reviews, this chapter will present a minimal Methods section for one mammalian cell type and an extended Notes section, focusing on aspects that are problematic or not well described in the literature. Most of the presented work involves how to segment the data to produce a complete, progressive, and compartmentalized cell cycle analysis from early G1 to late mitosis (telophase). A more recent development, using fluorescent proteins fused with proteins or peptides that are degraded by ubiquitination during specific periods of the cell cycle, termed "Fucci" (fluorescent, ubiquitination-based cell cycle indicators) provide an analysis similar in concept to multiple antibody labeling, except in this case cells can be analyzed while living and transgenic organisms can be created to perform cell cycle analysis ex or in vivo (Sakaue-Sawano et al., Cell 132:487-498, 2007). This technology will not be discussed.

  19. Thermal cycle efficiency of the indirect combined HTGR-GT power generation system

    Energy Technology Data Exchange (ETDEWEB)

    Muto, Yasushi [Japan Atomic Energy Research Inst., Tokai, Ibaraki (Japan). Tokai Research Establishment

    1996-02-01

    High thermal efficiency of 50% could be expected in a power generation system coupling a high temperature gas-cooled reactor(HTGR) with a closed cycle gas turbine(GT). There are three candidate systems such as a direct cycle(DC), an indirect cycle(ICD) and an indirect combined cycle(IDCC). The IDCC could solve many problems in both the DC and the IDC and consists of a primary circuit and a secondary circuit where a topping cycle is a Brayton cycle and a bottoming cycle is a steam cycle. In this report, the thermal cycle efficiency of the IDCC is examined regarding configurations of components and steam pressure. It has been shown that there are two types of configurations, that is, a perfect cascade type and a semi-cascade one and the latter can be further classified into Case A, Case B and Case C. The conditions achieving the maximum thermal cycle efficiency were revealed for these cases. In addition, the optimum system configurations were proposed considering the thermal cycle efficiency, safety and plant arrangement. (author).

  20. Cycle to Cycle Variation Study in a Dual Fuel Operated Engine

    KAUST Repository

    Pasunurthi, Shyamsundar; Jupudi, Ravichandra; Wijeyakulasuriya, Sameera; Gubba, Sreenivasa Rao; Im, Hong G.; Jaasim, Mohammed; Primus, Roy; Klingbeil, Adam; Finney, Charles

    2017-01-01

    The standard capability of engine experimental studies is that ensemble averaged quantities like in-cylinder pressure from multiple cycles and emissions are reported and the cycle to cycle variation (CCV) of indicated mean effective pressure (IMEP

  1. Performances of four magnetic heat-pump cycles

    International Nuclear Information System (INIS)

    Chen, F.C.; Murphy, R.W.; Mel, V.C.; Chen, G.L.

    1990-01-01

    Magnetic heat pumps have been successfully used for refrigeration applications at near absolute-zero-degree temperatures. In these applications, a temperature lift of a few degrees in a cryogenic environment is sufficient and can be easily achieved by a simple magnetic heat-pump cycle. To extend magnetic heat pumping to other temperature ranges and other types of applications in which the temperature lift is more than just a few degrees requires more involved cycle processes. This paper investigates the characteristics of a few better-known thermomagnetic heat-pump cycles (Carnot, Ericsson, Stirling, and regenerative) in extended ranges of temperature lift. The regenerative cycle is the most efficient one. For gadolinium operating between 0 and 7 T (Tesla) in a heat pump cycle with a heat-rejection temperature of 320 K, our analysis predicted a 42% loss in coefficient of performance at 260 K cooling temperature, and a 15% loss in capacity at 232 K cooling temperature for the constant-field cycle as compared with the ideal regenerative cycle. Such substantial penalties indicate that the potential irreversibilities from this one source (the additional heat transfer that would be needed for the constant-field vs. the ideal regenerative cycle) may adversely affect the viability of certain proposed MHP concepts if the relevant loss mechanisms are not adequately addressed

  2. Naturalistic drive cycle synthesis for pickup trucks.

    Science.gov (United States)

    Liu, Zifan; Ivanco, Andrej; Filipi, Zoran

    2015-09-01

    Future pick-up trucks are meeting much stricter fuel economy and exhaust emission standards. Design tradeoffs will have to be carefully evaluated to satisfy consumer expectations within the regulatory and cost constraints. Boundary conditions will obviously be critical for decision making: thus, the understanding of how customers are driving in naturalistic settings is indispensable. Federal driving schedules, while critical for certification, do not capture the richness of naturalistic cycles, particularly the aggressive maneuvers that often shape consumer perception of performance. While there are databases with large number of drive cycles, applying all of them directly in the design process is impractical. Therefore, representative drive cycles that capture the essence of the naturalistic driving should be synthesized from naturalistic driving data. Naturalistic drive cycles are firstly categorized by investigating their micro-trip components, defined as driving activities between successive stops. Micro-trips are expected to characterize underlying local traffic conditions, and separate different driving patterns. Next, the transitions from one vehicle state to another vehicle state in each cycle category are captured with Transition Probability Matrix (TPM). Candidate drive cycles can subsequently be synthesized using Markov Chain based on TPMs for each category. Finally, representative synthetic drive cycles are selected through assessment of significant cycle metrics to identify the ones with smallest errors. This paper provides a framework for synthesis of representative drive cycles from naturalistic driving data, which can subsequently be used for efficient optimization of design or control of pick-up truck powertrains. Manufacturers will benefit from representative drive cycles in several aspects, including quick assessments of vehicle performance and energy consumption in simulations, component sizing and design, optimization of control strategies, and

  3. Wave Engine Topping Cycle Assessment

    Science.gov (United States)

    Welch, Gerard E.

    1996-01-01

    The performance benefits derived by topping a gas turbine engine with a wave engine are assessed. The wave engine is a wave rotor that produces shaft power by exploiting gas dynamic energy exchange and flow turning. The wave engine is added to the baseline turboshaft engine while keeping high-pressure-turbine inlet conditions, compressor pressure ratio, engine mass flow rate, and cooling flow fractions fixed. Related work has focused on topping with pressure-exchangers (i.e., wave rotors that provide pressure gain with zero net shaft power output); however, more energy can be added to a wave-engine-topped cycle leading to greater engine specific-power-enhancement The energy addition occurs at a lower pressure in the wave-engine-topped cycle; thus the specific-fuel-consumption-enhancement effected by ideal wave engine topping is slightly lower than that effected by ideal pressure-exchanger topping. At a component level, however, flow turning affords the wave engine a degree-of-freedom relative to the pressure-exchanger that enables a more efficient match with the baseline engine. In some cases, therefore, the SFC-enhancement by wave engine topping is greater than that by pressure-exchanger topping. An ideal wave-rotor-characteristic is used to identify key wave engine design parameters and to contrast the wave engine and pressure-exchanger topping approaches. An aerodynamic design procedure is described in which wave engine design-point performance levels are computed using a one-dimensional wave rotor model. Wave engines using various wave cycles are considered including two-port cycles with on-rotor combustion (valved-combustors) and reverse-flow and through-flow four-port cycles with heat addition in conventional burners. A through-flow wave cycle design with symmetric blading is used to assess engine performance benefits. The wave-engine-topped turboshaft engine produces 16% more power than does a pressure-exchanger-topped engine under the specified topping

  4. Three Cycles of Radiofrequency Ablation Are More Efficacious Than Two in the Management of Morton's Neuroma.

    Science.gov (United States)

    Brooks, David; Parr, Adam; Bryceson, William

    2018-04-01

    Morton's neuroma is a common cause of forefoot pain. Outcomes of conservative therapy are mixed and many patients undergo operative intervention. Radiofrequency ablation has recently gained favor as a treatment option, although the optimal regime is unknown. This study investigates the effectiveness of 2 versus 3 cycles of radiofrequency ablation for the treatment of Morton's neuroma. We surveyed a cohort of patients with Morton's neuroma who had progressed to radiofrequency ablation after failed conservative treatment. Patients received either 2 or 3 cycles of radiofrequency ablation by a single surgeon. We assessed patients based on their change in numerical pain rating scale, symptom improvement, complications, and progression to surgical excision through a series of telephone interviews. Outcomes between the 2 treatment arms were compared by parametric tests. Twenty-eight patients were included in the study. Eighteen patients with 21 neuromas received 2 cycles and 10 patients with 11 neuromas received 3 cycles. Mean time of follow-up was 12.9 months. Overall, 88% of patients were either very or moderately satisfied with their outcome. In patients who received 2 cycles mean numerical pain scores decreased from 7.9 ± 1.1 to 3.4 ± 2.4 postprocedure. Three patients progressed to operative excision. In patients who received 3 cycles, numerical pain scores decreased from 8.0 ± 1.0 to 1.5 ± 2.0 postprocedure. One patient progressed to operative excision. Patients who received 3 cycles had reduced medium-term pain postoperatively compared with 2 cycles (3.4 ± 2.4 vs 1.5 ± 2.0, P = .011). Radiofrequency ablation provides a high rate of patient satisfaction in the treatment of Morton's neuroma with few side effects. It appears that 3 cycles may be superior to 2 cycles but a randomized controlled trial will be required to confirm these results. Intervention, Level III: Comparative study without concurrent controls.

  5. Rotary Stirling-Cycle Engine And Generator

    Science.gov (United States)

    Chandler, Joseph A.

    1990-01-01

    Proposed electric-power generator comprises three motor generators coordinated by microprocessor and driven by rotary Stirling-cycle heat engine. Combination offers thermodynamic efficiency of Stirling cycle, relatively low vibration, and automatic adjustment of operating parameters to suit changing load on generator. Rotary Stirling cycle engine converts heat to power via compression and expansion of working gas between three pairs of rotary pistons on three concentric shafts in phased motion. Three motor/generators each connected to one of concentric shafts, can alternately move and be moved by pistons. Microprocessor coordinates their operation, including switching between motor and generator modes at appropriate times during each cycle.

  6. Combined Turbine and Cycle Optimization for Organic Rankine Cycle Power Systems—Part A: Turbine Model

    Directory of Open Access Journals (Sweden)

    Andrea Meroni

    2016-04-01

    Full Text Available Axial-flow turbines represent a well-established technology for a wide variety of power generation systems. Compactness, flexibility, reliability and high efficiency have been key factors for the extensive use of axial turbines in conventional power plants and, in the last decades, in organic Rankine cycle power systems. In this two-part paper, an overall cycle model and a model of an axial turbine were combined in order to provide a comprehensive preliminary design of the organic Rankine cycle unit, taking into account both cycle and turbine optimal designs. Part A presents the preliminary turbine design model, the details of the validation and a sensitivity analysis on the main parameters, in order to minimize the number of decision variables in the subsequent turbine design optimization. Part B analyzes the application of the combined turbine and cycle designs on a selected case study, which was performed in order to show the advantages of the adopted methodology. Part A presents a one-dimensional turbine model and the results of the validation using two experimental test cases from literature. The first case is a subsonic turbine operated with air and investigated at the University of Hannover. The second case is a small, supersonic turbine operated with an organic fluid and investigated by Verneau. In the first case, the results of the turbine model are also compared to those obtained using computational fluid dynamics simulations. The results of the validation suggest that the model can predict values of efficiency within ± 1.3%-points, which is in agreement with the reliability of classic turbine loss models such as the Craig and Cox correlations used in the present study. Values similar to computational fluid dynamics simulations at the midspan were obtained in the first case of validation. Discrepancy below 12 % was obtained in the estimation of the flow velocities and turbine geometry. The values are considered to be within a

  7. Fuel cycle economics of HTRs

    Energy Technology Data Exchange (ETDEWEB)

    Hansen, U.

    1975-06-15

    The High Temperature Reactor commands a unique fuel cycle flexibility and alternative options are open to the utilities. The reference thorium reactor operating in the U-233 recycle mode is 10 to 20% cheaper than the low-enriched reactor; however, the thorium cycle depends on the supply of 93% enriched uranium and the availability of reprocessing and refabrication facilities to utilize its bred fissile material. The economic landscape towards the end of the 20th Century will presumably be dominated by pronounced increases in the costs of natural resources. In the case of nuclear energy, resource considerations are reflected in the price of uranium, which is expected Lo have reached 50 $/lbm U3O8 in the early 1990s and around 100 $/lbm U3O8 around 2010. In this economic environment the fuel cycle advantage of the thorium system amounts to some 20% and is capable of absorbing substantial expenses in bringing about the closing of the out-of-pile cycle. A most attractive aspect of the HTR fuel cycle flexibility is for the utility to start operating the reactor on the low enriched uranium cycle and at a later date switch over to the thorium cycle as this becomes economically more and more attractive. The incentive amounts to some 50 M$ in terms of present worth money at the time of decision making, assumed to take place 10 years after start-up. The closing of the thorium cycle is of paramount importance and a step to realize this objective lies in simplifying the head-end reprocessing technology by abandoning the segregation concept of feed and breed coated particles in the reference cycle. A one-coated-particle scheme in which all discharged uranium isotopes are recycled in mixed oxide particles is feasible and suffers a very minor economic penalty only.

  8. Serum Thyrotropin and Phase of the Menstrual Cycle

    Directory of Open Access Journals (Sweden)

    Salvatore Benvenga

    2017-09-01

    Full Text Available About one-fifth of patients treated with levothyroxine have serum thyrotropin (TSH above target concentrations but, in approximately 15% of them, the cause of this TSH insufficient normalization remains unknown. We report the cases of two regularly menstruating women with known thyroid disease who had TSH levels consistently >3 mU/L (and sometimes above target levels during mid-cycle, but consistently lower serum levels during the follicular and luteal phases of menstrual cycle. A major TSH release by the thyrotrophs in response to high circulating levels of estradiol (E2 at mid-cycle may increase levels of TSH compared to other phases of the cycle. The increased TSH can be misinterpreted as refractory hypothyroidism if the woman is under L-T4 replacement therapy or as subclinical hypothyroidism if the woman is not. Our findings might have important implications for diagnosis and management of thyroid disease, suggesting to request serum TSH measurements outside of the periovulatory days.

  9. Solar-cycle period-amplitude relation as evidence of hysteresis of the solar-cycle nonlinear magnetic oscillation and the long-term (55 year) cyclic modulation

    International Nuclear Information System (INIS)

    Yoshimura, H.

    1979-01-01

    A new dynamical model of the solar cycle has predicted that the cycle should have a hysteretic nature: the behavior of each 11 year cycle should depend on previous cycles. In the light of this new understanding of the dynamical mechanism of the solar cycle, Waldmeier's (hypothetical) law was examined as a yet unexplained characteristic of the cycle by studying the observed sunspot frequency curve. Contrary to this hypothetical law, however, it was found that sunspot cycle curves did not form a single-parameter family characterized by the maximum amplitude of the cycle. The evolutionary trajectories in period-amplitude phase space verified the hysteretic nature of the observed cycle and revealed long-term (55 year instead of the previously claimed 80 year) periodic modulations, called here 55 year grand cycles. Each 55 year grand cycle forms a loop in the phase space, and the characteristics of each 11 year cycle depend on its position in the ascending or descending phase of the grand cycle. This new law was analyzed by the nonlinear multiple-period dynamo oscillation model which has predicted the hysteretic nature. The era from cycle 11 to cycle 15 turned out to be an anomalous one characterized by alternating amplitudes for odd and even cycles. Cycles 16--20 seem to constitute one grand cycle. If this is true, cycle 21 would be the beginning of another grand maximum and the model predicts that its duration would be short

  10. Fast breeder fuel cycle

    International Nuclear Information System (INIS)

    1978-07-01

    This contribution is prepared for the answer to the questionnaire of working group 5, subgroup B. B.1. is the short review of the fast breeder fuel cycles based on the reference large commercial Japanese LMFBR. The LMFBRs are devided into two types. FBR-A is the reactor to be used before 2000, and its burnup and breeding ratio are relatively low. The reference fuel cycle requirement is calculated based on the FBR-A. FBR-B is the one to be used after 2000, and its burnup and breeding ratio are relatively high. B.2. is basic FBR fuel reprocessing scheme emphasizing the differences with LWR reprocessing. This scheme is based on the conceptual design and research and development work on the small scale LMFBR reprocessing facility of Japan. The facility adopts a conventional PUREX process except head end portions. The report also describes the effects of technical modifications of conventional reprocessing flow sheets, and the problems to be solved before the adoption of these alternatives

  11. Out-of-core nuclear fuel cycle economic optimization for nonequilibrium cycles

    International Nuclear Information System (INIS)

    Comes, S.A.

    1987-01-01

    A methodology and associated computer code was developed to determine near-optimum out-of-core fuel management strategies. The code, named OCEON (Out-of-Core Economic OptimizationN), identified feed-region sizes and enrichments, and partially burned fuel-reload strategies for each cycle of a multi-cycle planning horizon, subject to cycle-energy requirements and constraints on feed enrichments, discharge burnups, and the moderator temperature coefficient. A zero-dimensional reactor physics model, enhanced by a linear reactivity model to provide batch power shares, performs the initial feed enrichment, burnup and constraint evaluations, while a two-dimensional, nodal code is used to refine the calculations for the final solutions. The economic calculations are performed rapidly using an annuity-factor-based model. Use of Monte Carlo integer programming to select the optimum solutions allows for the determination of a family of near-optimum solutions, from which engineering judgment may be used to select an appropriate strategy. Results from various nonequilibrium cycle energy requirement cases typically show a large number of low-cost solutions near the optimum. This confirms that the Monte Carlo integer programming approach of generating a family of solutions will be most useful for selecting optimum strategies when other considerations, such as incore loading pattern concerns, must be addressed

  12. Energy systems. Tome 3: advanced cycles, low environmental impact innovative systems; Systeme energetiques, TOME 3: cycles avances, systemes innovants a faible impact environnemental

    Energy Technology Data Exchange (ETDEWEB)

    Gicquel, R

    2009-07-01

    This third tome about energy systems completes the two previous ones by showing up advanced thermodynamical cycles, in particular having a low environmental impact, and by dealing with two other questions linked with the study of systems with a changing regime operation: - the time management of energy, with the use of thermal and pneumatic storage systems and time simulation (schedule for instance) of systems (solar energy type in particular); - the technological dimensioning and non-nominal regime operation studies. Because this last topic is particularly complex, new functionalities have been implemented mainly by using the external classes mechanism, which allows the user to freely personalize his models. This tome is illustrated with about 50 examples of cycles modelled with Thermoptim software. Content: foreword; 1 - generic external classes; 2 - advanced gas turbine cycles; 3 - evaporation-concentration, mechanical steam compression, desalination, hot gas drying; 4 - cryogenic cycles; 5 - electrochemical converters; 6 - global warming, CO{sub 2} capture and sequestration; 7 - future nuclear reactors (coupled to Hirn and Brayton cycles); 8 - thermodynamic solar cycles; 10 - pneumatic and thermal storage; 11 - calculation of thermodynamic solar facilities; 12 - problem of technological dimensioning and non-nominal regime; 13 - exchangers modeling and parameterizing for the dimensioning and the non-nominal regime; 14 - modeling and parameterizing of volumetric compressors; 15 - modeling and parameterizing of turbo-compressors and turbines; 16 - identification methodology of component parameters; 17 - case studies. (J.S.)

  13. Thermodynamic Optimization of Supercritical CO{sub 2} Brayton Cycles

    Energy Technology Data Exchange (ETDEWEB)

    Rhim, Dong-Ryul; Park, Sung-Ho; Kim, Su-Hyun; Yeom, Choong-Sub [Institute for Advanced Engineering, Yongin (Korea, Republic of)

    2015-05-15

    The supercritical CO{sub 2} Brayton cycle has been studied for nuclear applications, mainly for one of the alternative power conversion systems of the sodium cooled fast reactor, since 1960's. Although the supercritical CO{sub 2} Brayton cycle has not been expected to show higher efficiency at lower turbine inlet temperature over the conventional steam Rankine cycle, the higher density of supercritical CO{sub 2} like a liquid in the supercritical region could reduce turbo-machinery sizes, and the potential problem of sodium-water reaction with the sodium cooled fast reactor might be solved with the use of CO{sub 2} instead of water. The supercritical CO{sub 2} recompression Brayton cycle was proposed for the better thermodynamic efficiency than for the simple supercritical CO{sub 2} Brayton cycle. Thus this paper presents the efficiencies of the supercritical CO{sub 2} recompression Brayton cycle along with several decision variables for the thermodynamic optimization of the supercritical CO{sub 2} recompression Brayton cycle. The analytic results in this study show that the system efficiency reaches its maximum value at a compressor outlet pressure of 200 bars and a recycle fraction of 30 %, and the lower minimum temperature approach at the two heat exchangers shows higher system efficiency as expected.

  14. Life Cycle Management

    DEFF Research Database (Denmark)

    Bey, Niki

    2018-01-01

    This chapter gives an overview of Life Cycle Management (LCM)—a discipline that deals with the managerial tasks related to practicing sustainable development in an organisation . Just as Life Cycle Assessment, LCM advocates the life cycle perspective , and it applies this perspective in decision...

  15. BWROPT: A multi-cycle BWR fuel cycle optimization code

    Energy Technology Data Exchange (ETDEWEB)

    Ottinger, Keith E.; Maldonado, G. Ivan, E-mail: Ivan.Maldonado@utk.edu

    2015-09-15

    Highlights: • A multi-cycle BWR fuel cycle optimization algorithm is presented. • New fuel inventory and core loading pattern determination. • The parallel simulated annealing algorithm was used for the optimization. • Variable sampling probabilities were compared to constant sampling probabilities. - Abstract: A new computer code for performing BWR in-core and out-of-core fuel cycle optimization for multiple cycles simultaneously has been developed. Parallel simulated annealing (PSA) is used to optimize the new fuel inventory and placement of new and reload fuel for each cycle considered. Several algorithm improvements were implemented and evaluated. The most significant of these are variable sampling probabilities and sampling new fuel types from an ordered array. A heuristic control rod pattern (CRP) search algorithm was also implemented, which is useful for single CRP determinations, however, this feature requires significant computational resources and is currently not practical for use in a full multi-cycle optimization. The PSA algorithm was demonstrated to be capable of significant objective function reduction and finding candidate loading patterns without constraint violations. The use of variable sampling probabilities was shown to reduce runtime while producing better results compared to using constant sampling probabilities. Sampling new fuel types from an ordered array was shown to have a mixed effect compared to random new fuel type sampling, whereby using both random and ordered sampling produced better results but required longer runtimes.

  16. One-dimensional two-fluid model for wavy flow beyond the Kelvin–Helmholtz instability: Limit cycles and chaos

    Energy Technology Data Exchange (ETDEWEB)

    Lopez de Bertodano, Martín, E-mail: bertodan@purdue.edu [School of Nuclear Engineering, Purdue University, West Lafayette, IN 47907 (United States); Fullmer, William D. [Department of Chemical and Biological Engineering, U. of Colorado, Boulder, CO 80309 (United States); Clausse, Alejandro [CNEA-CONICET and Universidad Nacional del Centro, 7000 Tandil (Argentina)

    2016-12-15

    A 1D TFM numerical simulation of near horizontal stratified two-phase flow is performed where the TFM, including surface tension and viscous stresses, is simplified to a two-equation model using the fixed-flux approximation. As the angle of inclination of the channel increases so does the driving body force, so the flow becomes KH unstable, and waves grow and develop nonlinearities. It is shown that these waves grow until they reach a limit cycle due to viscous dissipation at wave fronts. Upon further inclination of the channel, chaos is observed. The appearance of chaos in a 1D TFM implies a nonlinear process that transfers energy intermittently from long wavelengths where energy is produced to short wavelengths where energy is dissipated by viscosity, so that an averaged energy equilibrium in frequency space is attained. This is comparable to the well-known turbulent stability mechanism of the multi-dimensional Navier–Stokes equations, i.e., chaos implies Lyapunov stability, but in this case it is strictly a two-phase phenomenon.

  17. Nash-Williams’ cycle-decomposition theorem

    DEFF Research Database (Denmark)

    Thomassen, Carsten

    2016-01-01

    We give an elementary proof of the theorem of Nash-Williams that a graph has an edge-decomposition into cycles if and only if it does not contain an odd cut. We also prove that every bridgeless graph has a collection of cycles covering each edge at least once and at most 7 times. The two results...

  18. Large-scale fuel cycle centres

    International Nuclear Information System (INIS)

    Smiley, S.H.; Black, K.M.

    1977-01-01

    The US Nuclear Regulatory Commission (NRC) has considered the nuclear energy centre concept for fuel cycle plants in the Nuclear Energy Centre Site Survey 1975 (NECSS-75) Rep. No. NUREG-0001, an important study mandated by the US Congress in the Energy Reorganization Act of 1974 which created the NRC. For this study, the NRC defined fuel cycle centres as consisting of fuel reprocessing and mixed-oxide fuel fabrication plants, and optional high-level waste and transuranic waste management facilities. A range of fuel cycle centre sizes corresponded to the fuel throughput of power plants with a total capacity of 50,000-300,000MW(e). The types of fuel cycle facilities located at the fuel cycle centre permit the assessment of the role of fuel cycle centres in enhancing the safeguard of strategic special nuclear materials - plutonium and mixed oxides. Siting fuel cycle centres presents a smaller problem than siting reactors. A single reprocessing plant of the scale projected for use in the USA (1500-2000t/a) can reprocess fuel from reactors producing 50,000-65,000MW(e). Only two or three fuel cycle centres of the upper limit size considered in the NECSS-75 would be required in the USA by the year 2000. The NECSS-75 fuel cycle centre evaluation showed that large-scale fuel cycle centres present no real technical siting difficulties from a radiological effluent and safety standpoint. Some construction economies may be achievable with fuel cycle centres, which offer opportunities to improve waste-management systems. Combined centres consisting of reactors and fuel reprocessing and mixed-oxide fuel fabrication plants were also studied in the NECSS. Such centres can eliminate shipment not only of Pu but also mixed-oxide fuel. Increased fuel cycle costs result from implementation of combined centres unless the fuel reprocessing plants are commercial-sized. Development of Pu-burning reactors could reduce any economic penalties of combined centres. The need for effective fissile

  19. Quality Improvement Cycles that Reduced Waiting Times at ...

    African Journals Online (AJOL)

    It was decided to undertake quality improvement (QI) cycles to analyse and improve the situation, using waiting time as a measure of improvement. Methods: A QI team was chosen to conduct two QI cycles. The allocated time for QI cycle 1 was from May to August 2006 and for QI cycle 2 from September to December 2006.

  20. New insight into regenerated air heat pump cycle

    International Nuclear Information System (INIS)

    Zhang, Chun-Lu; Yuan, Han; Cao, Xiang

    2015-01-01

    Regenerated air (reverse Brayton) cycle has unique potentials in heat pump applications compared to conventional vapor-compression cycles. To better understand the regenerated air heat pump cycle characteristics, a thermodynamic model with new equivalent parameters was developed in this paper. Equivalent temperature ratio and equivalent isentropic efficiency of expander were introduced to represent the effect of regenerator, which made the regenerated air cycle in the same mathematical expressions as the basic air cycle and created an easy way to prove some important features that regenerated air cycle inherits from the basic one. Moreover, we proved in theory that the regenerator does not always improve the air cycle efficiency. Larger temperature ratio and lower effectiveness of regenerator could make the regenerated air cycle even worse than the basic air cycle. Lastly, we found that only under certain conditions the cycle could get remarkable benefits from a well-sized regenerator. These results would enable further study of the regenerated air cycle from a different perspective. - Highlights: • A thermodynamic model for regenerated air heat pump cycle was developed. • Equivalent temperature ratio and equivalent expander efficiency were introduced. • We proved regenerated air cycle can make heating capacity in line with heating load. • We proved the regenerator does not always improve the air cycle efficiency.

  1. Radioactive Waste Generation in Pyro-SFR Nuclear Fuel Cycle

    International Nuclear Information System (INIS)

    Gao, Fanxing; Park, Byung Heung; Ko, Won Il

    2011-01-01

    Which nuclear fuel cycle option to deploy is of great importance in the sustainability of nuclear power. SFR fuel cycle employing pyroprocessing (named as Pyro- SFR Cycle) is one promising fuel cycle option in the near future. Radioactive waste generation is a key criterion in nuclear fuel cycle system analysis, which considerably affects the future development of nuclear power. High population with small territory is one special characteristic of ROK, which makes the waste management pretty important. In this study, particularly the amount of waste generation with regard to the promising advanced fuel cycle option was evaluated, because the difficulty of deploying an underground repository for HLW disposal requires a longer time especially in ROK

  2. Monitoring of Freeze-Thaw Cycles in Concrete Using Embedded Sensors and Ultrasonic Imaging

    Science.gov (United States)

    Ranz, Javier; Aparicio, Sofía; Romero, Héctor; Casati, María Jesús; Molero, Miguel; González, Margarita

    2014-01-01

    This paper deals with the study of damage produced during freeze-thaw (F-T) cycles using two non-destructive measurement approaches—the first approach devoted to continuous monitoring using embedded sensors during the cycles, and the second one, performing ultrasonic imaging before and after the cycles. Both methodologies have been tested in two different types of concrete specimens, with and without air-entraining agents. Using the first measurement approach, the size and distribution of pores were estimated using a thermoporometrical model and continuous measurements of temperature and ultrasonic velocity along cycles. These estimates have been compared with the results obtained using mercury porosimetry testing. In the second approach, the damage due to F-T cycles has been evaluated by automated ultrasonic transmission and pulse-echo inspections made before and after the cycles. With these inspections the variations in the dimensions, velocity and attenuation caused by the accelerated F-T cycles were determined. PMID:24481231

  3. Studies of a Combined-Cycle Engine

    OpenAIRE

    苅田, 丈士; KANDA, Takeshi

    2003-01-01

    For a Single-Stage-to-Orbit (SSTO) aerospace plane (Fig.1), several engines will be necessary to reach orbit. The combined-cycle engine incorporates several operational modes in a single engine. Study of the combined cycle engine has a long history, and several kinds of such engines have been proposed and studied. When several engines are mounted on a vehicle, each engine of the system will show a performance higher than that of the combined cycle engine. However, during the operation of one ...

  4. Sulfur cycle

    Digital Repository Service at National Institute of Oceanography (India)

    LokaBharathi, P.A.

    Microbes, especially bacteria, play an important role in oxidative and reductive cycle of sulfur. The oxidative part of the cycle is mediated by photosynthetic bacteria in the presence of light energy and chemosynthetic forms in the absence of light...

  5. Fast Reactor Fuel Cycle Cost Estimates for Advanced Fuel Cycle Studies

    International Nuclear Information System (INIS)

    Harrison, Thomas

    2013-01-01

    Presentation Outline: • Why Do I Need a Cost Basis?; • History of the Advanced Fuel Cycle Cost Basis; • Description of the Cost Basis; • Current Work; • Fast Reactor Fuel Cycle Applications; • Sample Fuel Cycle Cost Estimate Analysis; • Future Work

  6. Exergy analysis of helium liquefaction systems based on modified Claude cycle with two-expanders

    Science.gov (United States)

    Thomas, Rijo Jacob; Ghosh, Parthasarathi; Chowdhury, Kanchan

    2011-06-01

    Large-scale helium liquefaction systems, being energy-intensive, demand judicious selection of process parameters. An effective tool for design and analysis of thermodynamic cycles for these systems is exergy analysis, which is used to study the behavior of a helium liquefaction system based on modified Claude cycle. Parametric evaluation using process simulator Aspen HYSYS® helps to identify the effects of cycle pressure ratio and expander flow fraction on the exergetic efficiency of the liquefaction cycle. The study computes the distribution of losses at different refrigeration stages of the cycle and helps in selecting optimum cycle pressures, operating temperature levels of expanders and mass flow rates through them. Results from the analysis may help evolving guidelines for designing appropriate thermodynamic cycles for practical helium liquefaction systems.

  7. Cycle accurate and cycle reproducible memory for an FPGA based hardware accelerator

    Science.gov (United States)

    Asaad, Sameh W.; Kapur, Mohit

    2016-03-15

    A method, system and computer program product are disclosed for using a Field Programmable Gate Array (FPGA) to simulate operations of a device under test (DUT). The DUT includes a device memory having a number of input ports, and the FPGA is associated with a target memory having a second number of input ports, the second number being less than the first number. In one embodiment, a given set of inputs is applied to the device memory at a frequency Fd and in a defined cycle of time, and the given set of inputs is applied to the target memory at a frequency Ft. Ft is greater than Fd and cycle accuracy is maintained between the device memory and the target memory. In an embodiment, a cycle accurate model of the DUT memory is created by separating the DUT memory interface protocol from the target memory storage array.

  8. Mathematical modeling of the complete thermodynamic cycle of a new Atkinson cycle gas engine

    International Nuclear Information System (INIS)

    Shojaeefard, Mohammad Hassan; Keshavarz, Mojtaba

    2015-01-01

    The Atkinson cycle provides the potential to increase the efficiency of SI engines using overexpansion concept. This also will suggest decrease in CO_2 generation by internal combustion engine. In this study a mathematical modeling of complete thermodynamic cycle of a new two-stroke Atkinson cycle SI engine will be presented. The mathematical modeling is carried out using two-zone combustion analysis in order to make the model predict exhaust emission so that its values could be compared with the values of conventional SI engine. The model also is validated against experimental tests in that increase in efficiency is achieved compared to conventional SI engines. - Highlights: • The complete cycle model for the rotary Atkinson engine was developed. • Comparing the results with experimental data shows good model validity. • The model needs further improvement for the scavenging phase. • There is 5% increment in thermal efficiency with new engine compared to conventional SI engines.

  9. Essays on economic cycles

    NARCIS (Netherlands)

    Groot, de E.A. (Bert)

    2006-01-01

    Schumpeter’s line of thought of multiple economic cycles is further investigated. The existence of multiple cycles in economic variables is demonstrated. In basic innovations five different cycles are found. Multiple cycle structures are shown in various macro-economic variables from the United

  10. HEMISPHERIC HELICITY TREND FOR SOLAR CYCLE 24

    International Nuclear Information System (INIS)

    Hao Juan; Zhang Mei

    2011-01-01

    Using vector magnetograms obtained with the Spectro-polarimeter (SP) on board Hinode satellite, we studied two helicity parameters (local twist and current helicity) of 64 active regions that occurred in the descending phase of solar cycle 23 and the ascending phase of solar cycle 24. Our analysis gives the following results. (1) The 34 active regions of the solar cycle 24 follow the so-called hemispheric helicity rule, whereas the 30 active regions of the solar cycle 23 do not. (2) When combining all 64 active regions as one sample, they follow the hemispheric helicity sign rule as in most other observations. (3) Despite the so-far most accurate measurement of vector magnetic field given by SP/Hinode, the rule is still weak with large scatters. (4) The data show evidence of different helicity signs between strong and weak fields, confirming previous result from a large sample of ground-based observations. (5) With two example sunspots we show that the helicity parameters change sign from the inner umbra to the outer penumbra, where the sign of penumbra agrees with the sign of the active region as a whole. From these results, we speculate that both the Σ-effect (turbulent convection) and the dynamo have contributed in the generation of helicity, whereas in both cases turbulence in the convection zone has played a significant role.

  11. The integration of fast reactor to the fuel cycle in Slovakia

    International Nuclear Information System (INIS)

    Zajac, R.; Darilek, P.; Necas, V.

    2009-01-01

    A very topical problem of nuclear power is the fuel cycle back-end. One of the options is a LWR spent fuel reprocessing and a fissile nuclides re-use in the fast reactor. A large amount of spent fuel has been stored in the power plant intermediate storage during the operation of WWER-440 reactors in Slovakia. This paper is based on an analysis of Pu and minor actinides content in actual WWER-440 spent fuel stored in Slovakia. The next part presents the possibilities of reprocessing and Pu re-use in fast reactor under Slovak conditions. The fuel cycle consisting of the WWER-440 reactor, PUREX reprocessing plant and a sodium fast reactor was designed. The last section compares two parts of this fuel cycle: one is UOX cycle in WWER-440 reactor and the other is cycle in the fast reactor - SUPER PHENIX loaded with MOX fuel (Pu + Minor Actinides). The starting point is a single recycling of Pu from WWER-440 in the fission products. The next step is multi recycling of Pu in the fission products to obtain equilibrium cycle. This article is dealing with the solution of power production and fuel cycle indicators. All kinds of calculations were performed by computer code HELIOS 1.10. (Authors)

  12. The integration of fast reactor to the fuel cycle in Slovakia

    International Nuclear Information System (INIS)

    Zajac, R.; Darilek, P.; Necas, V.

    2009-01-01

    A very topical problem of nuclear power is the fuel cycle back-end. One of the options is a LWR spent fuel reprocessing and a fissile nuclides re-use in the fast reactor. A large amount of spent fuel has been stored in the power plant intermediate storage during the operation of VVER-440 reactors in Slovakia. This paper is based on an analysis of Pu and minor actinides content in actual VVER-440 spent fuel stored in Slovakia. The next part presents the possibilities of reprocessing and Pu re-use in fast reactor under Slovak conditions. The fuel cycle consisting of the VVER-440 reactor, PUREX reprocessing plant and a sodium fast reactor was designed. The last section compares two parts of this fuel cycle: one is UOX cycle in VVER-440 reactor and the other is cycle in the fast reactor - SUPER PHENIX loaded with MOX fuel (Pu + Minor Actinides). The starting point is a single recycling of Pu from VVER-440 in the FR. The next step is multirecycling of Pu in the FR to obtain equilibrium cycle. This article is dealing with the solution of power production and fuel cycle indicators. All kinds of calculations were performed by computer code HELIOS 1.10. (authors)

  13. Nuclear-fuel-cycle education: Module 1. Nuclear fuel cycle overview

    International Nuclear Information System (INIS)

    Eckhoff, N.D.

    1981-07-01

    This educational module is an overview of the nuclear-fule-cycle. The overview covers nuclear energy resources, the present and future US nuclear industry, the industry view of nuclear power, the International Nuclear Fuel Cycle Evaluation program, the Union of Concerned Scientists view of the nuclear-fuel-cycle, an analysis of this viewpoint, resource requirements for a model light water reactor, and world nuclear power considerations

  14. Thorium cycles and proliferation

    International Nuclear Information System (INIS)

    Lovins, A.B.

    1979-01-01

    This paper analyzes several prevalent misconceptions about nuclear fuel cycles that breed fissile uranium-233 from thorium. Its main conclusions are: U-233, despite the gamma radioactivity of associated isotopes, is a rather attractive material for making fission bombs, and is a credible material for subnational as well as national groups to use for this purpose; (2) pure thorium cycles, which in effect merely substitute U-233 for Pu, would take many decades and much U to establish, and offer no significant safeguards advantage over Pu, cycles; (3) denatured Th-U cycles, which dilute the U-233 with inert U-238 to a level not directly usable in bombs, are not an effective safeguard even against subnational bomb-making; (4) several other features of mixed Th-U cycles are rather unattractive from a safeguards point of view; (5) thus, Th cycles of any kind are not a technical fix for proliferation (national or subnational) and, though probably more safeguardable than Pu cycles, are less so than once-through U cycles that entail no reprocessing; (6) while thorium cycles have some potential technical advantages, including flexibility, they cannot provide major savings in nuclear fuel resources compared to simpler ways of saving neutrons and U; and (7) while advocates of nuclear power may find Th cycles worth exploring, such cycles do not differ fundamentally from U cycles in any of the respects--including safeguards and fuel resources--that are relevant to the broader nuclear debate, and should not be euphorically embraced as if they did

  15. Temporal, seasonal and weather effects on cycle volume: an ecological study

    Directory of Open Access Journals (Sweden)

    Tin Tin Sandar

    2012-03-01

    Full Text Available Abstract Background Cycling has the potential to provide health, environmental and economic benefits but the level of cycling is very low in New Zealand and many other countries. Adverse weather is often cited as a reason why people do not cycle. This study investigated temporal and seasonal variability in cycle volume and its association with weather in Auckland, New Zealand's largest city. Methods Two datasets were used: automated cycle count data collected on Tamaki Drive in Auckland by using ZELT Inductive Loop Eco-counters and weather data (gust speed, rain, temperature, sunshine duration available online from the National Climate Database. Analyses were undertaken using data collected over one year (1 January to 31 December 2009. Normalised cycle volumes were used in correlation and regression analyses to accommodate differences by hour of the day and day of the week and holiday. Results In 2009, 220,043 bicycles were recorded at the site. There were significant differences in mean hourly cycle volumes by hour of the day, day type and month of the year (p p Conclusions There are temporal and seasonal variations in cycle volume in Auckland and weather significantly influences hour-to-hour and day-to-day variations in cycle volume. Our findings will help inform future cycling promotion activities in Auckland.

  16. The effect of elevated progesterone levels before HCG triggering in modified natural cycle frozen-thawed embryo transfer cycles

    DEFF Research Database (Denmark)

    Groenewoud, Eva R; Macklon, Nick S; Cohlen, Ben J

    2017-01-01

    follicular phase progesterone levels may occur in unstimulated cycles before frozen-thawed embryo transfer, or what affect they may have on outcomes. In this cohort study, 271 patients randomized to the modified natural cycle arm of a randomized controlled trial comparing two endometrial preparation regimens....... Whether monitoring of progesterone and LH in natural cycle frozen-thawed embryo transfer has added clinical value should studied further....

  17. Drivers of cycling demand and cycling futures in the Danish context

    DEFF Research Database (Denmark)

    Analysis of the time trend in cycling mode share based on longest possible time series. Logistic regression model of cycling as mode choice as basis for studying ‘driver variables’ contribution to time trend. Describing important vectors of change behind the time trend.......Analysis of the time trend in cycling mode share based on longest possible time series. Logistic regression model of cycling as mode choice as basis for studying ‘driver variables’ contribution to time trend. Describing important vectors of change behind the time trend....

  18. Evidence for the Existence of One Antenna-Associated, Lipid-Dissolved and Two Protein-Bound Pools of Diadinoxanthin Cycle Pigments in Diatoms[C][W

    Science.gov (United States)

    Lepetit, Bernard; Volke, Daniela; Gilbert, Matthias; Wilhelm, Christian; Goss, Reimund

    2010-01-01

    We studied the localization of diadinoxanthin cycle pigments in the diatoms Cyclotella meneghiniana and Phaeodactylum tricornutum. Isolation of pigment protein complexes revealed that the majority of high-light-synthesized diadinoxanthin and diatoxanthin is associated with the fucoxanthin chlorophyll protein (FCP) complexes. The characterization of intact cells, thylakoid membranes, and pigment protein complexes by absorption and low-temperature fluorescence spectroscopy showed that the FCPs contain certain amounts of protein-bound diadinoxanthin cycle pigments, which are not significantly different in high-light and low-light cultures. The largest part of high-light-formed diadinoxanthin cycle pigments, however, is not bound to antenna apoproteins but located in a lipid shield around the FCPs, which is copurified with the complexes. This lipid shield is primarily composed of the thylakoid membrane lipid monogalactosyldiacylglycerol. We also show that the photosystem I (PSI) fraction contains a tightly connected FCP complex that is enriched in protein-bound diadinoxanthin cycle pigments. The peripheral FCP and the FCP associated with PSI are composed of different apoproteins. Tandem mass spectrometry analysis revealed that the peripheral FCP is composed mainly of the light-harvesting complex protein Lhcf and also significant amounts of Lhcr. The PSI fraction, on the other hand, shows an enrichment of Lhcr proteins, which are thus responsible for the diadinoxanthin cycle pigment binding. The existence of lipid-dissolved and protein-bound diadinoxanthin cycle pigments in the peripheral antenna and in PSI is discussed with respect to different specific functions of the xanthophylls. PMID:20935178

  19. The two chromosomes of Vibrio cholerae are initiated at different time points in the cell cycle

    DEFF Research Database (Denmark)

    Rasmussen, Tue; Jensen, Rasmus Bugge; Skovgaard, Ole

    2007-01-01

    for analysing flow cytometry data and marker frequency analysis, we show that the small chromosome II is replicated late in the C period of the cell cycle, where most of chromosome I has been replicated. Owing to the delay in initiation of chromosome II, the two chromosomes terminate replication...... at approximately the same time and the average number of replication origins per cell is higher for chromosome I than for chromosome II. Analysis of cell-cycle parameters shows that chromosome replication and segregation is exceptionally fast in V. cholerae. The divided genome and delayed replication of chromosome...... II may reduce the metabolic burden and complexity of chromosome replication by postponing DNA synthesis to the last part of the cell cycle and reducing the need for overlapping replication cycles during rapid proliferation...

  20. Optimised heat recovery steam generators for integrated solar combined cycle plants

    Science.gov (United States)

    Peterseim, Jürgen H.; Huschka, Karsten

    2017-06-01

    The cost of concentrating solar power (CSP) plants is decreasing but, due to the cost differences and the currently limited value of energy storage, implementation of new facilities is still slow compared to photovoltaic systems. One recognized option to lower cost instantly is the hybridization of CSP with other energy sources, such as natural gas or biomass. Various references exist for the combination of CSP with natural gas in combined cycle plants, also known as Integrated Solar Combined Cycle (ISCC) plants. One problem with current ISCC concepts is the so called ISCC crisis, which occurs when CSP is not contributing and cycle efficiency falls below efficiency levels of solely natural gas only fired combined cycle plants. This paper analyses current ISCC concepts and compares them with two optimised designs. The comparison is based on a Kuraymat type ISCC plant and shows that cycle optimization enables a net capacity increase of 1.4% and additional daily generation of up to 7.9%. The specific investment of the optimised Integrated Solar Combined Cycle plant results in a 0.4% cost increase, which is below the additional net capacity and daily generation increase.

  1. Reversible and irreversible heat engine and refrigerator cycles

    Science.gov (United States)

    Leff, Harvey S.

    2018-05-01

    Although no reversible thermodynamic cycles exist in nature, nearly all cycles covered in textbooks are reversible. This is a review, clarification, and extension of results and concepts for quasistatic, reversible and irreversible processes and cycles, intended primarily for teachers and students. Distinctions between the latter process types are explained, with emphasis on clockwise (CW) and counterclockwise (CCW) cycles. Specific examples of each are examined, including Carnot, Kelvin and Stirling cycles. For the Stirling cycle, potentially useful task-specific efficiency measures are proposed and illustrated. Whether a cycle behaves as a traditional refrigerator or heat engine can depend on whether it is reversible or irreversible. Reversible and irreversible-quasistatic CW cycles both satisfy Carnot's inequality for thermal efficiency, η ≤ η C a r n o t . Irreversible CCW cycles with two reservoirs satisfy the coefficient of performance inequality K ≤ K C a r n o t . However, an arbitrary reversible cycle satisfies K ≥ K C a r n o t when compared with a reversible Carnot cycle operating between its maximum and minimum temperatures, a potentially counterintuitive result.

  2. High-Energy Solar Particle Events in Cycle 24

    Science.gov (United States)

    Gopalswamy, N.; Makela, P.; Yashiro, S.; Xie, H.; Akiyama, S.; Thakur, N.

    2015-01-01

    The Sun is already in the declining phase of cycle 24, but the paucity of high-energy solar energetic particle (SEP) events continues with only two ground level enhancement (GLE) events as of March 31, 2015. In an attempt to understand this, we considered all the large SEP events of cycle 24 that occurred until the end of 2014. We compared the properties of the associated CMEs with those in cycle 23. We found that the CME speeds in the sky plane were similar, but almost all those cycle-24 CMEs were halos. A significant fraction of (16%) of the frontside SEP events were associated with eruptive prominence events. CMEs associated with filament eruption events accelerate slowly and attain peak speeds beyond the typical GLE release heights. When we considered only western hemispheric events that had good connectivity to the CME nose, there were only 8 events that could be considered as GLE candidates. One turned out to be the first GLE event of cycle 24 (2012 May 17). In two events, the CMEs were very fast (>2000 km/s) but they were launched into a tenuous medium (high Alfven speed). In the remaining five events, the speeds were well below the typical GLE CME speed (2000 km/s). Furthermore, the CMEs attained their peak speeds beyond the typical heights where GLE particles are released. We conclude that several factors contribute to the low rate of high-energy SEP events in cycle 24: (i) reduced efficiency of shock acceleration (weak heliospheric magnetic field), (ii) poor latitudinal and longitudinal connectivity), and (iii) variation in local ambient conditions (e.g., high Alfven speed).

  3. Cell cycle gene expression under clinorotation

    Science.gov (United States)

    Artemenko, Olga

    2016-07-01

    Cyclins and cyclin-dependent kinase (CDK) are main regulators of the cell cycle of eukaryotes. It's assumes a significant change of their level in cells under microgravity conditions and by other physical factors actions. The clinorotation use enables to determine the influence of gravity on simulated events in the cell during the cell cycle - exit from the state of quiet stage and promotion presynthetic phase (G1) and DNA synthesis phase (S) of the cell cycle. For the clinorotation effect study on cell proliferation activity is the necessary studies of molecular mechanisms of cell cycle regulation and development of plants under altered gravity condition. The activity of cyclin D, which is responsible for the events of the cell cycle in presynthetic phase can be controlled by the action of endogenous as well as exogenous factors, but clinorotation is one of the factors that influence on genes expression that regulate the cell cycle.These data can be used as a model for further research of cyclin - CDK complex for study of molecular mechanisms regulation of growth and proliferation. In this investigation we tried to summarize and analyze known literature and own data we obtained relatively the main regulators of the cell cycle in altered gravity condition.

  4. Life-cycle cost analysis of adsorption cycles for desalination

    KAUST Repository

    Thu, Kyaw; Chakraborty, A.; Saha, B.B.; Chun, Won Gee; Ng, K.C.

    2010-01-01

    This paper presents the thermo-economic analysis of the adsorption desalination (AD) cycle that is driven by low-temperature waste heat from exhaust of industrial processes or renewable sources. The AD cycle uses an adsorbent such as the silica gel

  5. Nuclear power fuel cycle

    International Nuclear Information System (INIS)

    Havelka, S.; Jakesova, L.

    1982-01-01

    Economic problems are discussed of the fuel cycle (cost of the individual parts of the fuel cycle and the share of the fuel cycle in the price of 1 kWh), the technological problems of the fuel cycle (uranium ore mining and processing, uranium isotope enrichment, the manufacture of fuel elements, the building of long-term storage sites for spent fuel, spent fuel reprocessing, liquid and gaseous waste processing), and the ecologic aspects of the fuel cycle. (H.S.)

  6. 40 CFR 1065.514 - Cycle-validation criteria for operation over specified duty cycles.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 32 2010-07-01 2010-07-01 false Cycle-validation criteria for operation over specified duty cycles. 1065.514 Section 1065.514 Protection of Environment ENVIRONMENTAL... Over Specified Duty Cycles § 1065.514 Cycle-validation criteria for operation over specified duty...

  7. Benefits of cycle stretchout in pressurized water reactor extended-burnup fuel cycles

    International Nuclear Information System (INIS)

    Matzie, R.A.; Leung, D.C.; Liu, Y.; Beekmann, R.W.

    1981-01-01

    Nuclear reactors are inherently capable of operating for a substantial period beyond their nominal end of cycle (EOC) as a result of negative moderator and fuel temperature coefficients and the decrease in xenon poisoning with lower core power levels. This inherent capability can be used to advantage to reduce annual uranium makeup requirements and cycle energy costs by the use of planned EOC stretchout. This paper discusses the fuel utilization efficiency and economics of both the five-batch, extended-burnup cycle and the three-batch, standard-burnup cycle, which can be improved by employing planned EOC (end of cycle) stretchout. 11 refs

  8. Denatured fuel cycles

    International Nuclear Information System (INIS)

    Till, C.E.

    1979-01-01

    This paper traces the history of the denatured fuel concept and discusses the characteristics of fuel cycles based on the concept. The proliferation resistance of denatured fuel cycles, the reactor types they involve, and the limitations they place on energy generation potential are discussed. The paper concludes with some remarks on the outlook for such cycles

  9. Canthin-6-one induces cell death, cell cycle arrest and differentiation in human myeloid leukemia cells.

    Science.gov (United States)

    Vieira Torquato, Heron F; Ribeiro-Filho, Antonio C; Buri, Marcus V; Araújo Júnior, Roberto T; Pimenta, Renata; de Oliveira, José Salvador R; Filho, Valdir C; Macho, Antonio; Paredes-Gamero, Edgar J; de Oliveira Martins, Domingos T

    2017-04-01

    Canthin-6-one is a natural product isolated from various plant genera and from fungi with potential antitumor activity. In the present study, we evaluate the antitumor effects of canthin-6-one in human myeloid leukemia lineages. Kasumi-1 lineage was used as a model for acute myeloid leukemia. Cells were treated with canthin-6-one and cell death, cell cycle and differentiation were evaluated in both total cells (Lin + ) and leukemia stem cell population (CD34 + CD38 - Lin -/low ). Among the human lineages tested, Kasumi-1 was the most sensitive to canthin-6-one. Canthin-6-one induced cell death with apoptotic (caspase activation, decrease of mitochondrial potential) and necrotic (lysosomal permeabilization, double labeling of annexin V/propidium iodide) characteristics. Moreover, canthin-6-one induced cell cycle arrest at G 0 /G 1 (7μM) and G 2 (45μM) evidenced by DNA content, BrdU incorporation and cyclin B1/histone 3 quantification. Canthin-6-one also promoted differentiation of Kasumi-1, evidenced by an increase in the expression of myeloid markers (CD11b and CD15) and the transcription factor PU.1. Furthermore, a reduction of the leukemic stem cell population and clonogenic capability of stem cells were observed. These results show that canthin-6-one can affect Kasumi-1 cells by promoting cell death, cell cycle arrest and cell differentiation depending on concentration used. Canthin-6-one presents an interesting cytotoxic activity against leukemic cells and represents a promising scaffold for the development of molecules for anti-leukemic applications, especially by its anti-leukemic stem cell activity. Copyright © 2017 Elsevier B.V. All rights reserved.

  10. Large-scale fuel cycle centers

    International Nuclear Information System (INIS)

    Smiley, S.H.; Black, K.M.

    1977-01-01

    The United States Nuclear Regulatory Commission (NRC) has considered the nuclear energy center concept for fuel cycle plants in the Nuclear Energy Center Site Survey - 1975 (NECSS-75) -- an important study mandated by the U.S. Congress in the Energy Reorganization Act of 1974 which created the NRC. For the study, NRC defined fuel cycle centers to consist of fuel reprocessing and mixed oxide fuel fabrication plants, and optional high-level waste and transuranic waste management facilities. A range of fuel cycle center sizes corresponded to the fuel throughput of power plants with a total capacity of 50,000 - 300,000 MWe. The types of fuel cycle facilities located at the fuel cycle center permit the assessment of the role of fuel cycle centers in enhancing safeguarding of strategic special nuclear materials -- plutonium and mixed oxides. Siting of fuel cycle centers presents a considerably smaller problem than the siting of reactors. A single reprocessing plant of the scale projected for use in the United States (1500-2000 MT/yr) can reprocess the fuel from reactors producing 50,000-65,000 MWe. Only two or three fuel cycle centers of the upper limit size considered in the NECSS-75 would be required in the United States by the year 2000 . The NECSS-75 fuel cycle center evaluations showed that large scale fuel cycle centers present no real technical difficulties in siting from a radiological effluent and safety standpoint. Some construction economies may be attainable with fuel cycle centers; such centers offer opportunities for improved waste management systems. Combined centers consisting of reactors and fuel reprocessing and mixed oxide fuel fabrication plants were also studied in the NECSS. Such centers can eliminate not only shipment of plutonium, but also mixed oxide fuel. Increased fuel cycle costs result from implementation of combined centers unless the fuel reprocessing plants are commercial-sized. Development of plutonium-burning reactors could reduce any

  11. Edgeworth cycles revisited

    International Nuclear Information System (INIS)

    Doyle, Joseph; Muehlegger, Erich; Samphantharak, Krislert

    2010-01-01

    Some gasoline markets exhibit remarkable price cycles, where price spikes are followed by a series of small price declines: a pattern consistent with a model of Edgeworth cycles described by Maskin and Tirole. We extend the model and empirically test its predictions with a new dataset of daily station-level prices in 115 US cities. Consistent with the theory, and often in contrast with previous empirical work, we find the least and most concentrated markets are much less likely to exhibit cycling behavior both within and across cities; areas with more independent convenience-store gas stations are also more likely to cycle. (author)

  12. Consecutive cycles of hospital accreditation

    DEFF Research Database (Denmark)

    Falstie-Jensen, Anne Mette; Bogh, Søren Bie; Johnsen, Søren Paaske

    2018-01-01

    Objective: To examine the association between compliance with consecutive cycles of accreditation and patient-related outcomes. Design: A Danish nationwide population-based study from 2012 to 2015. Setting: In-patients admitted with one of the 80 diagnoses at public, non-psychiatric hospitals....... Participants: In-patients admitted with one of 80 primary diagnoses which accounted for 80% of all deaths occuring within 30 dyas after admission. Intervention: Admission to a hospital with high (n = 125 485 in-patients) or low compliance (n = 152 074 in-patients) in both cycles of accreditation by the Danish...... admission (adjusted OR: 1.26 (95% CI: 1.11-1.43) and a longer LOS (adjusted HR of discharge: 0.89 (95% CI: 0.82-0.95) than in-patients at high compliant hospitals. No difference was seen for acute readmission (adjusted HR: 0.98 (95% CI: 0.90-1.06)). Focusing on the second cycle alone, in...

  13. Cycle-by-cycle exhaust temperature monitoring for detection of misfiring and combustion instability in reciprocating natural gas engines

    Energy Technology Data Exchange (ETDEWEB)

    Gardiner, D.P. [Nexum Research Corp., Kingston, ON (Canada); Bardon, M.F. [Royal Military Coll. of Canada, Kingston, ON (Canada). Dept. of Mechanical Engineering

    2007-07-01

    The effectiveness of a cycle-by-cycle exhaust temperature monitoring system on engines operating at or near their fully rate load capacity was examined. Tests were conducted on stationary industrial natural gas engines. The study evaluated the monitoring system's ability to detect isolated single misfires, as well as combustion instability during misfire-free operations when the air/fuel ratio of the engine was adjusted to progressively lower settings. The combustion instability level of the engines was quantified by determining the relative variability of the groups of consecutive cycles. The coefficient of variation of indicated mean effective pressure (COV of IMEP) was used to examine cyclic variability. A combustion instability index was used to quantify cyclic variability with cycle-by-cycle exhaust temperature monitoring. Two engines were tested, notably a Cummins QSK 19G turbocharged natural gas engine; and a Waukesha VHP L5790G industrial natural gas engine. The tests demonstrated that cycle-by-cycle exhaust temperature monitoring system was capable of detecting misfiring and combustion instabilities in natural gas engines. 6 refs., 9 figs.

  14. Fuel cycle centres

    International Nuclear Information System (INIS)

    Hagen, M.

    1977-01-01

    The concept of co-locating and integrating fuel cycle facilities at one site is discussed. This concept offers considerable advantages, especially in minimizing the amount of radioactive material to be transported on public roads. Safeguards and physical protection as relating to such an integrated system of facilities are analysed in detail, also industrial and commercial questions. An overall risk-benefit evaluation turns out to be in favour of fuel cycle centres. These centres seem to be specifically attractive with regard to the back end of the fuel cycle, including on-site disposal of radioactive wastes. The respective German approach is presented as an example. Special emphasis is given to the site selection procedures in this case. Time scale and cost for the implementation of this concept are important factors to be looked at. Since participation of governmental institutions in these centres seems to be indispensable their respective roles as compared to industry must be clearly defined. The idea of adjusting fuel cycle centres to regional rather than national use might be an attractive option, depending on the specific parameters in the region, though results of existing multinational ventures are inconclusive in this respect. Major difficulties might be expected e.g. because of different national safety regulations and standards as well as commercial conditions among partner countries. Public acceptance in the host country seems to be another stumbling block for the realization of this type of multinational facilities

  15. Biomass fueled closed cycle gas turbine with water injection

    Energy Technology Data Exchange (ETDEWEB)

    Bardi, Silvia [Royal Inst. of Tech., Stockholm (Sweden). Dept. of Chemical Engineering and Technology

    2001-01-01

    Direct water injection has been studied for a small scale ({approx} 8 MW fuel input) closed cycle gas turbine coupled to a biomass fueled CFB furnace. Two different working fluids have been considered (helium-water mixture and nitrogen-water mixture). The water injection could take place between the compressor stages, as an intercooler, or after the high pressure compressor, as an aftercooler. Both this options have been studied, varying the relative humidity levels after the injection and the temperatures of the injected water. The effect of water injection on thermodynamic properties of the working fluids has been studied, together with its effect on turbomachinery isentropic efficiency. A sensitivity analysis on turbomachinery efficiency and cycle base pressure has been included. The results from this study have been compared to the performance of a dry closed cycle without water injection. The wet cycle shows an electric efficiency in the range 29-32% with helium-water mixture as working fluid and 30-32% with nitrogen-water mixture as working fluid, while the total efficiency (referring to the fuel LHV) is always higher than 100%. In the non-injected cycle the electric efficiency is 30-35% with helium and 32-36 with nitrogen. The total efficiency in the dry case with two level intercooling and postcooling is 87-89%, while is higher than 100% when only one stage inter- and postcooling is present. Aside from this, the study also includes a sizing of the heat exchangers for the different cycle variations. The heat transfer area is very sensible to the working fluid and to the amount of injected water and it's always higher when a nitrogen-water mixture is used. Compared to the cycle without water injection, by the way, the number of heat exchangers is reduced. This will lead to a lower pressure drop and a simpler plant layout. The total heat transfer area, however, is higher in the wet cycle than in the dry cycle.

  16. Primary water chemistry optimization for extended fuel cycle operation. Results of the 'Duo experimentation' after three cycles

    International Nuclear Information System (INIS)

    Viricel, L.; Andrieu, C.; Segura, J.C.; Rocher, A.; Thomazet, J.; Clinard, M.H.; Dacquait, F.

    2002-01-01

    The primary coolant conditioning in French nuclear power plants is essentially based on the boron-lithium coordinated chemistry, with a target pH of 7.2 at 300 C and a maximum lithium concentration of 2.2 mg/kg. In 1996, EDF 1300 MWe units began operating 18-month fuel cycles, increasing boron concentrations at the beginning of the cycles. Since today the maximum lithium concentration in normal operation is 2.2 mg/kg, extended cycle operation results in a decrease in the pH at the beginning of the cycles, which may possibly lead to deposits in RCS, and particularly on the fuel cladding, and increased dose rates. It has to be noted that today, the fuel assemblies maximum burnup is set at 52 GWd/tU. One solution is to adjust the pH by increasing the lithium content at the beginning of the cycles, which is easy to implement and does not require any modification on the units. Hence, EDF is testing a ''modified'' chemistry regime in the > during 4 fuel cycles, with a maximum authorized lithium content of 3.5 mg/kg at the beginning of the cycles in the Cattenom 2 pilot unit. The Golfech 1 reference unit implements a standard boron-lithium coordination pH 300 7.2. The major goal of the experimentation is to assess the impact of elevated lithium concentrations at the beginning of the cycles on fuel cladding oxide behavior, mass transport and dose rates. This paper presents the results of the first three cycles of the Duo experimentation. (author)

  17. Nuclear fuel cycle modelling using MESSAGE

    International Nuclear Information System (INIS)

    Guiying Zhang; Dongsheng Niu; Guoliang Xu; Hui Zhang; Jue Li; Lei Cao; Zeqin Guo; Zhichao Wang; Yutong Qiu; Yanming Shi; Gaoliang Li

    2017-01-01

    In order to demonstrate the possibilities of application of MESSAGE tool for the modelling of a Nuclear Energy System at the national level, one of the possible open nuclear fuel cycle options based on thermal reactors has been modelled using MESSAGE. The steps of the front-end and back-end of nuclear fuel cycle and nuclear reactor operation are described. The optimal structure for Nuclear Power Development and optimal schedule for introducing various reactor technologies and fuel cycle options; infrastructure facilities, nuclear material flows and waste, investments and other costs are demonstrated. (author)

  18. A hybrid mammalian cell cycle model

    Directory of Open Access Journals (Sweden)

    Vincent Noël

    2013-08-01

    Full Text Available Hybrid modeling provides an effective solution to cope with multiple time scales dynamics in systems biology. Among the applications of this method, one of the most important is the cell cycle regulation. The machinery of the cell cycle, leading to cell division and proliferation, combines slow growth, spatio-temporal re-organisation of the cell, and rapid changes of regulatory proteins concentrations induced by post-translational modifications. The advancement through the cell cycle comprises a well defined sequence of stages, separated by checkpoint transitions. The combination of continuous and discrete changes justifies hybrid modelling approaches to cell cycle dynamics. We present a piecewise-smooth version of a mammalian cell cycle model, obtained by hybridization from a smooth biochemical model. The approximate hybridization scheme, leading to simplified reaction rates and binary event location functions, is based on learning from a training set of trajectories of the smooth model. We discuss several learning strategies for the parameters of the hybrid model.

  19. Modulation of gene expression and cell-cycle signaling pathways by the EGFR inhibitor gefitinib (Iressa) in rat urinary bladder cancer.

    Science.gov (United States)

    Lu, Yan; Liu, Pengyuan; Van den Bergh, Francoise; Zellmer, Victoria; James, Michael; Wen, Weidong; Grubbs, Clinton J; Lubet, Ronald A; You, Ming

    2012-02-01

    The epidermal growth factor receptor inhibitor Iressa has shown strong preventive efficacy in the N-butyl-N-(4-hydroxybutyl)-nitrosamine (OH-BBN) model of bladder cancer in the rat. To explore its antitumor mechanism, we implemented a systems biology approach to characterize gene expression and signaling pathways in rat urinary bladder cancers treated with Iressa. Eleven bladder tumors from control rats, seven tumors from rats treated with Iressa, and seven normal bladder epithelia were profiled by the Affymetrix Rat Exon 1.0 ST Arrays. We identified 713 downregulated and 641 upregulated genes in comparing bladder tumors versus normal bladder epithelia. In addition, 178 genes were downregulated and 96 genes were upregulated when comparing control tumors versus Iressa-treated tumors. Two coexpression modules that were significantly correlated with tumor status and treatment status were identified [r = 0.70, P = 2.80 × 10(-15) (bladder tumor vs. normal bladder epithelium) and r = 0.63, P = 2.00 × 10(-42) (Iressa-treated tumor vs. control tumor), respectively]. Both tumor module and treatment module were enriched for genes involved in cell-cycle processes. Twenty-four and twenty-one highly connected hub genes likely to be key drivers in cell cycle were identified in the tumor module and treatment module, respectively. Analysis of microRNA genes on the array chips showed that tumor module and treatment module were significantly associated with expression levels of let-7c (r = 0.54, P = 3.70 × 10(-8) and r = 0.73, P = 1.50 × 10(-65), respectively). These results suggest that let-7c downregulation and its regulated cell-cycle pathway may play an integral role in governing bladder tumor suppression or collaborative oncogenesis and that Iressa exhibits its preventive efficacy on bladder tumorigenesis by upregulating let-7 and inhibiting the cell cycle. Cell culture study confirmed that the increased expression of let-7c decreases Iressa-treated bladder tumor cell

  20. The thorium fuel cycle in water-moderated reactor systems

    International Nuclear Information System (INIS)

    Critoph, E.

    1977-05-01

    Thorium and uranium cycles are compared with regard to reactor characteristics and technology, fuel-cycle technology, economic parameters, fuel-cycle costs, and system characteristics. In heavy-water reactors (HWRs) thorium cycles having uranium requirements at equilibrium ranging from zero to a quarter of those for the natural-uranium once-through cycle appear feasible. An 'inventory' of uranium of between 1 and 2 Mg/MW(e) is required for the transition to equilibrium. The cycles with the lowest uranium requirements compete with the others only at high uranium prices. Using thorium in light-water reactors, uranium requirements can be reduced by a factor of between two and three from the once-through uranium cycle. The light-water breeder reactor, promising zero uranium requirements at equilibrium, is being developed. Larger uranium inventories are required than for the HWRs. The lead time, from a decision to use thorium to significant impact on uranium utilization (compared to uranium cycle, recycling plutonium) is some two decades

  1. Partaking in cycling, at what cost? : determinants of cycling expenses

    NARCIS (Netherlands)

    Thibaut, E.; Vos, S.B.; Lagae, W.; Van Puyenbroeck, T.; Scheerder, J.

    2016-01-01

    This study analyses the determinants of cycling expenditure by means of a Tobit regression analysis, based on a dataset of 5,157 cyclists. Using a heterodox economic framework, 23 different variables are combined into two commonly used variable groups (socio-demographics, sports intensity variables)

  2. Estimating Externalities of Hydro Fuel Cycles, Report 6

    Energy Technology Data Exchange (ETDEWEB)

    Barnthouse, L.W.; Cada, G.F.; Cheng, M.-D.; Easterly, C.E.; Kroodsma, R.L.; Lee, R.; Shriner, D.S.; Tolbert, V.R.; Turner, R.S.

    1994-12-01

    There are three major objectives of this hydropower study: (1) to implement the methodological concepts that were developed in the background document (ORNL/RFF 1992) as a means of estimating the external costs and benefits of fuel cycles and, by so doing, to demonstrate their application to the hydroelectric fuel cycle (different fuel cycles have unique characteristics that need to be addressed in different ways); (2) to develop, given the time and resources, the best range of estimates of externalities associated with hydroelectric projects, using two benchmark projects at two reference sites in the US; and (3) to assess the state of the information that is available to support the estimation of externalities associated with the hydroelectric fuel cycle and, by so doing, to assist in identifying gaps in knowledge and in setting future research agendas. The main consideration in defining these objectives was a desire to have more information about externalities and a better method for estimating them. As set forth in the agreement between the US and the EC, the study is explicitly and intentionally not directed at any one audience. This study is about a methodology for estimating externalities. It is not about how to use estimates of externalities in a particular policy context.

  3. Thermospheric response observed over Fritz peak, Colorado, during two large geomagnetic storms near solar cycle maximum

    International Nuclear Information System (INIS)

    Hernandez, G.; Roble, R.G.; Ridley, E.C.; Allen, J.H.

    1982-01-01

    Nightime thermospheric winds and temperatures have been measured over Fritz Peak Observatory, Colorado (39.9 0 N, 105.5 0 W), with a high resolution Fabry-Perot spectrometer. The winds and temperatures are obtained from the Doppler shifts and line profiles of the (O 1) 15,867K (630 nm) line emission. Measurements made during two large geomagnetic storm periods near solar cycle maximum reveal a thermospheric response to the heat and momentum sources associated with these storms that is more complex than the ones measured near solar cycle minimum. In the earlier measurements made during solar cycle minimum, the winds to the north of Fritz Peak Observatory had an enhanced equatorward component and the winds to the south were also equatorward, usually with smaller velocities. The winds measured to the east and west of the observatory both had an enhanced westward wind component. For the two large storms near the present solar cycle maximum period converging winds are observed in each of the cardinal directions from Fritz Peak Observatory. These converging winds with speeds of hundreds of meters per second last for several hours. The measured neutral gas temperature in each of the directions also increases several hundred degrees Kelvin. Numerical experiments done with the NCAR thermospheric general circulation model (TGCM) suggest that the winds to the east and north of the station are driven by high-latitude heating and enhanced westward ion drag associated with magnetospheric convection. The cause of the enhanced poleward and eastward winds measured to the south and west of Fritz Peak Observatory, respectively, is not known. During geomagnetic quiet conditions the circulation is typically from the soutwest toward the northeast in the evening hours

  4. Development of Urban Driving Cycle with GPS Data Post Processing

    Directory of Open Access Journals (Sweden)

    Peter Lipar

    2016-08-01

    Full Text Available This paper presents GIS-based methodology for urban area driving cycle construction. The approach reaches beyond the frames of usual driving cycle development methods and takes into account another perspective of data collection. Rather than planning data collection, the approach is based on available in-vehicle measurement data post processing using Geographic Information Systems to manipulate the excessive database and extract only the representative and geographically limited individual trip data. With such data post processing the data was carefully adjusted to include only the data that describe representative driving in Ljubljana urban area. The selected method for the driving cycle development is based on searching for the best microtrips combination while minimizing the difference between two vectors; one based on generated cycle and the other on the database. Accounting for a large random sample of actual trip data, our approach enables more representative area-specific driving cycle development than the previously used techniques.

  5. Dynamic behavior of Rankine cycle system for waste heat recovery of heavy duty diesel engines under driving cycle

    International Nuclear Information System (INIS)

    Xie, Hui; Yang, Can

    2013-01-01

    Highlights: • Waste heat recovery behavior of the RCS during driving cycle was investigated. • Four operating modes were defined to describe the operating process of the RCS under driving cycle. • The operating mode switching is the crucial reason for on-road inefficiency. • The dry and isentropic fluids are superior to the wet ones on the adaptability to unsteady ExGE. • The effects of the vapor parameters on RCT-E and power mode percentage are opposite. - Abstract: The RCS (Rankine cycle system) used to recover the WHE (waste heat energy) from engines has been regarded as one of the most potential ways of achieving higher efficiency. However, it is of great challenge to keep the RCS still in good performance under driving cycle. This paper tries to reveal and explain its on-road inefficiency. The operating process of the RCS under driving cycle was analyzed in advance. Afterwards, four basic operating modes were defined, including startup mode, turbine turning mode, power mode and protection mode. Then, a RCS model was established and operating performances of the RCS under an actual driving cycle were discussed based on this model. The results indicate that the on-road RCS-E (Rankine cycle system efficiency) is as low as 3.63%, which is less than half of the design RCS-E (7.77%) at the rated operating point. Despite the inevitable vapor state fluctuation, it is the operating mode switching during the driving cycle that leads to the on-road inefficiency. Further investigations indicate that the expander safety temperature and its safety margin affected by the working fluids, designed superheat degree and evaporating pressure are the main factors determining the operating mode switching. Finally, the effects of the working fluids, designed superheat degree and evaporating pressure on the operating mode switching and RC (Rankine cycle) efficiencies were profoundly investigated. The study shows that the dry and isentropic fluids are superior to the wet

  6. Exergoeconomic comparison of TLC (trilateral Rankine cycle), ORC (organic Rankine cycle) and Kalina cycle using a low grade heat source

    International Nuclear Information System (INIS)

    Yari, M.; Mehr, A.S.; Zare, V.; Mahmoudi, S.M.S.; Rosen, M.A.

    2015-01-01

    Recently, the TLC (trilateral power cycle) has attracted significant interest as it provides better matching between the temperature profiles in the evaporator compared to conventional power cycles. This article investigates the performance of this cycle and compares it with those for the ORC (organic Rankine cycle) and the Kalina cycle, from the viewpoints of thermodynamics and thermoeconomics. A low-grade heat source with a temperature of 120 °C is considered for all the three systems. Parametric studies are performed for the systems for several working fluids in the ORC and TLC. The systems are then optimized for either maximum net output power or minimum product cost, using the EES (engineering equation solver) software. The results for the TLC indicate that an increase in the expander inlet temperature leads to an increase in net output power and a decrease in product cost for this power plant, whereas this is not the case for the ORC system. It is found that, although the TLC can achieve a higher net output power compared with the ORC and Kalina (KCS11 (Kalina cycle system 11)) systems, its product cost is greatly affected by the expander isentropic efficiency. It is also revealed that using n-butane as the working fluid can result in the lowest product cost in the ORC and the TLC. In addition, it is observed that, for both the ORC and Kalina systems, the optimum operating condition for maximum net output power differs from that for minimum product cost. - Highlights: • Exergoeconomic analysis of trilateral Rankine cycle is performed. • The system performance is compared with Organic Rankine and Kalina cycles. • Net power from trilateral Rankine cycle is higher than the other power systems. • Superiority of trilateral cycle depends on its expander isentropic efficiency

  7. Energy and exergy analysis of a closed Brayton cycle-based combined cycle for solar power tower plants

    International Nuclear Information System (INIS)

    Zare, V.; Hasanzadeh, M.

    2016-01-01

    Highlights: • A novel combined cycle is proposed for solar power tower plants. • The effects of solar subsystem and power cycle parameters are examined. • The proposed combined cycle yields exergy efficiencies of higher than 70%. • For the overall power plant exergy efficiencies of higher than 30% is achievable. - Abstract: Concentrating Solar Power (CSP) technology offers an interesting potential for future power generation and research on CSP systems of all types, particularly those with central receiver system (CRS) has been attracting a lot of attention recently. Today, these power plants cannot compete with the conventional power generation systems in terms of Levelized Cost of Electricity (LCOE) and if a competitive LCOE is to be reached, employing an efficient thermodynamic power cycle is deemed essential. In the present work, a novel combined cycle is proposed for power generation from solar power towers. The proposed system consists of a closed Brayton cycle, which uses helium as the working fluid, and two organic Rankine cycles which are employed to recover the waste heat of the Brayton cycle. The system is thermodynamically assessed from both the first and second law viewpoints. A parametric study is conducted to examine the effects of key operating parameters (including solar subsystem and power cycle parameters) on the overall power plant performance. The results indicate that exergy efficiencies of higher than 30% are achieved for the overall power plant. Also, according to the results, the power cycle proposed in this work has a better performance than the other investigated Rankine and supercritical CO_2 systems operating under similar conditions, for these types of solar power plants.

  8. Out-of-core fuel cycle optimization for nonequilibrium cycles

    International Nuclear Information System (INIS)

    Comes, S.A.; Turinsky, P.J.

    1988-01-01

    A methodology has been developed for determining the family of near-optimum fuel management schemes that minimize the levelized fuel cycle costs of a light water reactor over a multicycle planning horizon. Feed batch enrichments and sizes, burned batches to reinsert, and burnable poison loadings are determined for each cycle in the planning horizon. Flexibility in the methodology includes the capability to assess the economic benefits of various partially burned bath reload strategies as well as the effects of using split feed enrichments and enrichment palettes. Constraint limitations are imposed on feed enrichments, discharge burnups, moderator temperature coefficient, and cycle energy requirements

  9. Quantum thermodynamic cycles and quantum heat engines. II.

    Science.gov (United States)

    Quan, H T

    2009-04-01

    We study the quantum-mechanical generalization of force or pressure, and then we extend the classical thermodynamic isobaric process to quantum-mechanical systems. Based on these efforts, we are able to study the quantum version of thermodynamic cycles that consist of quantum isobaric processes, such as the quantum Brayton cycle and quantum Diesel cycle. We also consider the implementation of the quantum Brayton cycle and quantum Diesel cycle with some model systems, such as single particle in a one-dimensional box and single-mode radiation field in a cavity. These studies lay the microscopic (quantum-mechanical) foundation for Szilard-Zurek single-molecule engine.

  10. Predicting off-design range and performance of refrigeration cycle with two-stage centrifugal compressor and flash intercooler

    Energy Technology Data Exchange (ETDEWEB)

    Turunen-Saaresti, Teemu; Roeyttae, Pekka; Honkatukia, Juha; Backman, Jari [Lappeenranta University of Technology, Institute of Energy Technology, Laboratory of Fluid Dynamics, P.O. Box 20, 53851 Lappeenranta (Finland)

    2010-09-15

    A modern refrigeration process requires constant control to provide required cooling for the user. To properly and economically accommodate this need, a wide operation range of the compressor is necessary. Therefore, it is of interest to investigate the off-design operation of a cooling cycle and compressor. The refrigeration cycle equipped with a two-stage centrifugal compressor and a flash intercooler is studied. The compressor operation maps are generated with two different design codes and the operation values of the compressors are interpolated from the compressor maps in the simulation of the entire cooling cycle. Based on the previous studies of the utilised refrigeration cycle, R245fa is selected as coolant. The aim of this study is to demonstrate the control capacity of the centrifugal compressor and the performance of the cooling loop in off-design conditions. This configuration provides better and wider control over the cooling range than the traditional on-off control of displacement compressors. (author)

  11. One Cycle Fuels Another: The Energetics of Neurotransmitter Release.

    Science.gov (United States)

    Silm, Katlin; Edwards, Robert H

    2017-02-08

    In this issue of Neuron, Ashrafi et al. (2017) show that activity induces translocation of the insulin-regulated glucose transporter GLUT4 to the plasma membrane, where it sustains the ATP production required for synaptic vesicle cycling. However, translocation occurs from presynaptic membranes other than synaptic vesicles and involves a distinct molecular mechanism. Copyright © 2017 Elsevier Inc. All rights reserved.

  12. Candu reactors with thorium fuel cycles

    International Nuclear Information System (INIS)

    Hopwood, J.M.; Fehrenbach, P.; Duffey, R.; Kuran, S.; Ivanco, M.; Dyck, G.R.; Chan, P.S.W.; Tyagi, A.K.; Mancuso, C.

    2006-01-01

    Over the last decade and a half AECL has established a strong record of delivering CANDU 6 nuclear power plants on time and at budget. Inherently flexible features of the CANDU type reactors, such as on-power fuelling, high neutron economy, fuel channel based heat transport system, simple fuel bundle configuration, two independent shut down systems, a cool moderator and a defence-in-depth based safety philosophy provides an evolutionary path to further improvements in design. The immediate milestone on this path is the Advanced CANDU ReactorTM** (ACRTM**), in the form of the ACR-1000TM**. This effort is being followed by the Super Critical Water Reactor (SCWR) design that will allow water-cooled reactors to attain high efficiencies by increasing the coolant temperature above 550 0 C. Adaptability of the CANDU design to different fuel cycles is another technology advantage that offers an additional avenue for design evolution. Thorium is one of the potential fuels for future reactors due to relative abundance, neutronics advantage as a fertile material in thermal reactors and proliferation resistance. The Thorium fuel cycle is also of interest to China, India, and Turkey due to local abundance that can ensure sustainable energy independence over the long term. AECL has performed an assessment of both CANDU 6 and ACR-1000 designs to identify systems, components, safety features and operational processes that may need to be modified to replace the NU or SEU fuel cycles with one based on Thorium. The paper reviews some of these requirements and the associated practical design solutions. These modifications can either be incorporated into the design prior to construction or, for currently operational reactors, during a refurbishment outage. In parallel with reactor modifications, various Thorium fuel cycles, either based on mixed bundles (homogeneous) or mixed channels (heterogeneous) have been assessed for technical and economic viability. Potential applications of a

  13. Comparison of treatment outcome using two definitions of rapid cycling in subjects with bipolar II disorder.

    Science.gov (United States)

    Amsterdam, Jay D; Lorenzo-Luaces, Lorenzo; DeRubeis, Robert J

    2017-02-01

    We examined differences in treatment outcome between Diagnostic and Statistical Manual Fourth Edition (DSM-IV)-defined rapid cycling and average lifetime-defined rapid cycling in subjects with bipolar II disorder. We hypothesized that, compared with the DSM-IV definition, the average lifetime definition of rapid cycling may better identify subjects with a history of more mood lability and a greater likelihood of hypomanic symptom induction during long-term treatment. Subjects ≥18 years old with a bipolar II major depressive episode (n=129) were categorized into DSM-IV- and average lifetime-defined rapid cycling and prospectively treated with either venlafaxine or lithium monotherapy for 12 weeks. Responders (n=59) received continuation monotherapy for six additional months. These exploratory analyses found moderate agreement between the two rapid-cycling definitions (κ=0.56). The lifetime definition captured subjects with more chronic courses of bipolar II depression, whereas the DSM-IV definition captured subjects with more acute symptoms of hypomania. There was no difference between rapid-cycling definitions with respect to the response to acute venlafaxine or lithium monotherapy. However, the lifetime definition was slightly superior to the DSM-IV definition in identifying subjects who went on to experience hypomanic symptoms during continuation therapy. Although sample sizes were limited, the findings suggest that the lifetime definition of rapid cycling may identify individuals with a chronic rapid-cycling course and may also be slightly superior to the DSM-IV definition in identifying individuals with hypomania during relapse-prevention therapy. These findings are preliminary in nature and need replication in larger, prospective, bipolar II studies. © 2017 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  14. Comparison between two forms of vaginally administered progesterone for luteal phase support in assisted reproduction cycles.

    Science.gov (United States)

    Geber, Selmo; Moreira, Ana Carolina Ferreira; de Paula, Sálua Oliveira Calil; Sampaio, Marcos

    2007-02-01

    The use of progesterone for luteal phase support has been demonstrated to be beneficial in assisted reproduction cycles using gonadotrophin-releasing hormone analogues (GnRHa). Two micronized progesterone preparations are available for vaginal administration: capsules and gel. The objective of this study was to compare the efficacy of these two forms for luteal phase support in assisted reproduction cycles. A total of 244 couples undergoing IVF/intracytoplasmic sperm injection cycles were included in the study and were randomly allocated (sealed envelopes) into two groups: group 1 (122) received vaginal capsules of 200 mg of micronized progesterone (Utrogestan), 3 times daily, and group 2 (122) received micronized progesterone in gel (Crinone 8%), once daily. Both groups received progesterone for 13 days beginning day 1 after oocyte retrieval, continuing until the pregnancy test was performed and until 12 weeks of pregnancy. Groups were compared by clinical data and assisted reproduction results and had similar ages and causes of infertility. Although the pregnancy rate was higher for those receiving progesterone gel than capsules (44.26 and 36.06% respectively), this difference was not statistically significant. The study showed that vaginal progesterone gel and capsules used for luteal phase support in assisted reproduction cycles with long protocol GnRHa result in similar pregnancy rates.

  15. Comparative energy analysis on a new regenerative Brayton cycle

    International Nuclear Information System (INIS)

    Goodarzi, M.

    2016-01-01

    Highlights: • New regenerative Brayton cycle has been introduced. • New cycle has higher thermal efficiency and lower exhausted heat per output power. • Regenerator may remain useful in the new cycle even at high pressure ratio. • New regenerative Brayton cycle is suggested for low pressure ratio operations. - Abstract: Gas turbines are frequently used for power generation. Brayton cycle is the basis for gas turbine operation and developing the alternative cycles. Regenerative Brayton cycle is a developed cycle for basic Brayton cycle with higher thermal efficiency at low to moderate pressure ratios. A new regenerative Brayton cycle has been introduced in the present study. Energy analysis has been conducted on ideal cycles to compare them from the first law of thermodynamics viewpoint. Comparative analyses showed that the new regenerative Brayton cycle has higher thermal efficiency than the original one at the same pressure ratio, and also lower heat absorption and exhausted heat per unite output power. Computed results show that new cycle improves thermal efficiency from 12% to 26% relative to the original regenerative Brayton cycle in the range of studied pressure ratios. Contrary to the original regenerative Brayton cycle, regenerator remains useful in the new regenerative Brayton cycle even at higher pressure ratio.

  16. Low-cycle compression fatigue of reinforced concrete structures

    NARCIS (Netherlands)

    Stroeven, P.

    2010-01-01

    Paper reports on experiments performed in the low-cycle compression fatigue domain, considering two relatively high upper load levels and several lower ones. Two frequency levels were emphasized, i.e. 17.5 Hz and 0.175 Hz. An overview is given of characteristics of mechanical behaviour and of the

  17. Performance characteristics of a quantum Diesel refrigeration cycle

    International Nuclear Information System (INIS)

    He Jizhou; Wang Hao; Liu Sanqiu

    2009-01-01

    The Diesel refrigeration cycle using an ideal quantum gas as the working substance is called quantum Diesel refrigeration cycle, which is different from Carnot, Ericsson, Brayton, Otto and Stirling refrigeration cycles. For ideal quantum gases, a corrected equation of state, which considers the quantum behavior of gas particles, is used instead of the classical one. The purpose of this paper is to investigate the effect of quantum gas as the working substance on the performance of a quantum Diesel refrigeration cycle. It is found that coefficients of performance of the cycle are not affected by the quantum degeneracy of the working substance, which is the same as that of the classical Diesel refrigeration cycle. However, the refrigeration load is different from those of the classical Diesel refrigeration cycle. Lastly, the influence of the quantum degeneracy on the performance characteristics of the quantum Diesel refrigeration cycle operated in different temperature regions is discussed

  18. The uranium-plutonium breeder reactor fuel cycle

    International Nuclear Information System (INIS)

    Salmon, A.; Allardice, R.H.

    1979-01-01

    All power-producing systems have an associated fuel cycle covering the history of the fuel from its source to its eventual sink. Most, if not all, of the processes of extraction, preparation, generation, reprocessing, waste treatment and transportation are involved. With thermal nuclear reactors more than one fuel cycle is possible, however it is probable that the uranium-plutonium fuel cycle will become predominant; in this cycle the fuel is mined, usually enriched, fabricated, used and then reprocessed. The useful components of the fuel, the uranium and the plutonium, are then available for further use, the waste products are treated and disposed of safely. This particular thermal reactor fuel cycle is essential if the fast breeder reactor (FBR) using plutonium as its major fuel is to be used in a power-producing system, because it provides the necessary initial plutonium to get the system started. In this paper the authors only consider the FBR using plutonium as its major fuel, at present it is the type envisaged in all, current national plans for FBR power systems. The corresponding fuel cycle, the uranium-plutonium breeder reactor fuel cycle, is basically the same as the thermal reactor fuel cycle - the fuel is used and then reprocessed to separate the useful components from the waste products, the useful uranium and plutonium are used again and the waste disposed of safely. However the details of the cycle are significantly different from those of the thermal reactor cycle. (Auth.)

  19. Analysis of a combined Rankine-vapour-compression refrigeration cycle

    International Nuclear Information System (INIS)

    Aphornratana, Satha; Sriveerakul, Thanarath

    2010-01-01

    This paper describes a theoretical analysis of a heat-powered refrigeration cycle, a combined Rankine-vapour-compression refrigeration cycle. This refrigeration cycle combines an Organic Rankine Cycle and a vapour-compression cycle. The cycle can be powered by low grade thermal energy as low as 60 deg. C and can produce cooling temperature as low as -10 deg. C. In the analysis, two combined Rankine-vapour-compression refrigeration cycles were investigated: the system with R22 and the system with R134a. Calculated COP values between 0.1 and 0.6 of both the systems were found.

  20. Prediction of solar activity from solar background magnetic field variations in cycles 21-23

    International Nuclear Information System (INIS)

    Shepherd, Simon J.; Zharkov, Sergei I.; Zharkova, Valentina V.

    2014-01-01

    A comprehensive spectral analysis of both the solar background magnetic field (SBMF) in cycles 21-23 and the sunspot magnetic field in cycle 23 reported in our recent paper showed the presence of two principal components (PCs) of SBMF having opposite polarity, e.g., originating in the northern and southern hemispheres, respectively. Over a duration of one solar cycle, both waves are found to travel with an increasing phase shift toward the northern hemisphere in odd cycles 21 and 23 and to the southern hemisphere in even cycle 22. These waves were linked to solar dynamo waves assumed to form in different layers of the solar interior. In this paper, for the first time, the PCs of SBMF in cycles 21-23 are analyzed with the symbolic regression technique using Hamiltonian principles, allowing us to uncover the underlying mathematical laws governing these complex waves in the SBMF presented by PCs and to extrapolate these PCs to cycles 24-26. The PCs predicted for cycle 24 very closely fit (with an accuracy better than 98%) the PCs derived from the SBMF observations in this cycle. This approach also predicts a strong reduction of the SBMF in cycles 25 and 26 and, thus, a reduction of the resulting solar activity. This decrease is accompanied by an increasing phase shift between the two predicted PCs (magnetic waves) in cycle 25 leading to their full separation into the opposite hemispheres in cycle 26. The variations of the modulus summary of the two PCs in SBMF reveals a remarkable resemblance to the average number of sunspots in cycles 21-24 and to predictions of reduced sunspot numbers compared to cycle 24: 80% in cycle 25 and 40% in cycle 26.

  1. The low enriched uranium fuel cycle in Ontario

    International Nuclear Information System (INIS)

    Archinoff, G.H.

    1979-02-01

    Six fuel-cycle strategies for use in CANDU reactors are examined in terms of their uranium-conserving properties and their ease of commercialization for three assumed growth rates of installed nuclear capacity in Ontario. The fuel cycle strategies considered assume the continued use of the natural uranium cycle up to the mid-1990's. At that time, the low-enriched uranium (LEU) cycle is gradually introduced into the existing power generation grid. In the mid-2020's one of four advanced cycles is introduced. The advanced cycles considered are: mixed oxide, intermediate burn-up thorium (Pu topping), intermediate burn-up thorium (U topping), and LMFBR. For comparison purposes an all natural uranium strategy and a natural uranium-LEU strategy (with no advanced cycle) are also included. None of the strategies emerges as a clear, overall best choice. (LL)

  2. Investigation of thermodynamic performances for two solar-biomass hybrid combined cycle power generation systems

    International Nuclear Information System (INIS)

    Liu, Qibin; Bai, Zhang; Wang, Xiaohe; Lei, Jing; Jin, Hongguang

    2016-01-01

    Highlights: • Two solar-biomass hybrid combined cycle power generation systems are proposed. • The characters of the two proposed systems are compared. • The on-design and off-design properties of the system are numerically investigated. • The favorable performances of thermochemical hybrid routine are validated. - Abstract: Two solar-biomass hybrid combined cycle power generation systems are proposed in this work. The first system employs the thermochemical hybrid routine, in which the biomass gasification is driven by the concentrated solar energy, and the gasified syngas as a solar fuel is utilized in a combined cycle for generating power. The second system adopts the thermal integration concept, and the solar energy is directly used to heat the compressed air in the topping Brayton cycle. The thermodynamic performances of the developed systems are investigated under the on-design and off-design conditions. The advantages of the hybrid utilization technical mode are demonstrated. The solar energy can be converted and stored into the chemical fuel by the solar-biomass gasification, with the net solar-to-fuel efficiency of 61.23% and the net solar share of 19.01% under the specific gasification temperature of 1150 K. Meanwhile, the proposed system with the solar thermochemical routine shows more favorable behaviors, the annual system overall energy efficiency and the solar-to-electric efficiency reach to 29.36% and 18.49%, while the with thermal integration concept of 28.03% and 15.13%, respectively. The comparison work introduces a promising approach for the efficient utilization of the abundant solar and biomass resources in the western China, and realizes the mitigation of CO_2 emission.

  3. Nonlinear solar cycle forecasting: theory and perspectives

    Science.gov (United States)

    Baranovski, A. L.; Clette, F.; Nollau, V.

    2008-02-01

    In this paper we develop a modern approach to solar cycle forecasting, based on the mathematical theory of nonlinear dynamics. We start from the design of a static curve fitting model for the experimental yearly sunspot number series, over a time scale of 306 years, starting from year 1700 and we establish a least-squares optimal pulse shape of a solar cycle. The cycle-to-cycle evolution of the parameters of the cycle shape displays different patterns, such as a Gleissberg cycle and a strong anomaly in the cycle evolution during the Dalton minimum. In a second step, we extract a chaotic mapping for the successive values of one of the key model parameters - the rate of the exponential growth-decrease of the solar activity during the n-th cycle. We examine piece-wise linear techniques for the approximation of the derived mapping and we provide its probabilistic analysis: calculation of the invariant distribution and autocorrelation function. We find analytical relationships for the sunspot maxima and minima, as well as their occurrence times, as functions of chaotic values of the above parameter. Based on a Lyapunov spectrum analysis of the embedded mapping, we finally establish a horizon of predictability for the method, which allows us to give the most probable forecasting of the upcoming solar cycle 24, with an expected peak height of 93±21 occurring in 2011/2012.

  4. A prospective study of power cycles based on the expected sodium fast reactor parameters

    International Nuclear Information System (INIS)

    Herranz, L. E.; Linares, J. I.; Moratilla, B. Y.; Perez, G. D.

    2010-01-01

    One of the main issues that has not been solved yet in the frame of Sodium Fast Reactors (SFR) is to choose the most appropriate power conversion system. This paper explores the performance of different power cycles, from traditional to innovative layouts trying to find the optimized solution. Based on the expected reactor parameters (i.e., inlet and outlet coolant temperatures, 395 deg.C and 545 deg.C, respectively), a subcritical Rankine similar to those of fossil power plant cycles has been proposed as a reference layout. Then, alternative layouts based on innovative Rankine and Brayton cycles have been investigated. Two Rankine supercritical layouts have been modeled and analyzed: one of them, adopted from the Supercritical Water Reactor of GIV (one reheater, nine pre-heaters and one moisture separator) and the other similar to some fossil plants (two reheaters, nine pre-heaters with no moisture separator). Simple Brayton cycle configurations based on Helium has been also studied. Several layouts have been modeled to study the effects of: inter-cooling between compression stages, absence of an intermediate loop and coupling of an organic Rankine cycle (ORC). (authors)

  5. Morphologic changes in the vein after different numbers of radiofrequency ablation cycles.

    Science.gov (United States)

    Shaidakov, Evgeny V; Grigoryan, Arsen G; Korzhevskii, Dmitriy E; Ilyukhin, Evgeny A; Rosukhovski, Dmitriy A; Bulatov, Vasiliy L; Tsarev, Oleg I

    2015-10-01

    It has not yet been clarified whether it is possible to decrease the percentage of recurrences after radiofrequency (RF) ablation by way of increasing the number of RF ablation cycles. The aim of this study was to assess the morphologic changes in excised vein fragments after different durations of RF ablation exposure. In the first part of the study, we performed a morphologic analysis of eight cases of great saphenous vein (GSV) recanalization 6 months after RF ablation. The second part was performed on a suprafascial segment of the GSV with a length of >22 cm and a minimum diameter of 5 mm in 10 patients, who had given their consent to intraoperative excision of suprafascial GSV segments after RF ablation treatment through four 1-cm-long diametrical cuts. Prior ultrasound analysis had shown an average 6.9-mm diameter of the suprafascial segments. The segment was divided into three 7-cm-long subsegments and one control segment. The first, second, and third segments were treated with three, two, and one RF ablation cycles (ClosureFast; Covidien, Mansfield, Mass), respectively; the control segment was not exposed to RF ablation at all. Morphologic study of 160 sections of the vein (five sections of each segment and 10 control specimens) was carried out. The specimens were dyed with hematoxylin and orcein. The ensuing analysis was performed by an experienced expert with the blind study method (the specimens were numbered without any hint as to the quantity of RF ablation cycles performed on them). The intergroup comparison of the depth of venous wall damage was based on comparison of the coefficient of alteration, which is calculated as the relation of damage depth to thickness of the vein. After one RF ablation cycle, the depth of blurring of the structural elements only on some portions reached the middle of the muscle layer of the wall (coefficient of alteration, α = 26%). After two cycles, blurring of the structural elements on some portions extended to the

  6. The sunspot cycle revisited

    International Nuclear Information System (INIS)

    Lomb, Nick

    2013-01-01

    The set of sunspot numbers observed since the invention of the telescope is one of the most studied time series in astronomy and yet it is also one of the most complex. Fourteen frequencies are found in the yearly mean sunspot numbers from 1700 to 2011using the Lomb-Scargle periodogram and prewhitening. All of the frequencies corresponding to shorter term periods can be matched with simple algebraic combinations of the frequency of the main 11-year period and the frequencies of the longer term periods in the periodogram. This is exactly what can be expected from amplitude and phase modulation of an 11.12-year periodicity by longer term variations. Similar, though not identical, results are obtained after correcting the sunspot number series as proposed by Svalgaard. On looking separately at the amplitude and phase modulation a clear relationship is found between the two modulations although this relationship has broken down for the last four solar cycles. The phase modulation implies that there is a definite underlying period for the solar cycle. Such a clock mechanism does seem to be a possibility in models of the solar dynamo incorporating a conveyor-belt-like meridional circulation between high polar latitudes and the equator.

  7. Performance comparison of two low-CO2 emission solar/methanol hybrid combined cycle power systems

    International Nuclear Information System (INIS)

    Li, Yuanyuan; Zhang, Na; Lior, Noam

    2015-01-01

    Highlights: • Two novel solar hybrid combined cycle systems have been proposed and analyzed. • The power systems integrate solar-driven thermo-chemical conversion and CO 2 capture. • Exergy efficiency of about 55% and specific CO 2 emissions of 34 g/kW h are predicted. • Systems CO 2 emissions are 36.8% lower compared to a combined cycle with CO 2 capture. • The fossil fuel demand is ∼30% lower with a solar share of ∼20%. - Abstract: Two novel hybrid combined cycle power systems that use solar heat and methanol, and integrate CO 2 capture, are proposed and analyzed, one based on solar-driven methanol decomposition and the other on solar-driven methanol reforming. The high methanol conversion rates at relatively low temperatures offer the advantage of using the solar heat at only 200–300 °C to drive the syngas production by endothermic methanol conversions and its conversion to chemical energy. Pre-combustion decarbonization is employed to produce CO 2 -free fuel from the fully converted syngas, which is then burned to produce heat at the high temperature for power generation in the proposed advanced combined cycle systems. To improve efficiency, the systems’ configurations were based on the principle of cascade use of multiple heat sources of different temperatures. The thermodynamic performance of the hybrid power systems at its design point is simulated and evaluated. The results show that the hybrid systems can attain an exergy efficiency of about 55%, and specific CO 2 emissions as low as 34 g/kW h. Compared to a gas/steam combined cycle with flue gas CO 2 capture, the proposed solar-assisted system CO 2 emissions are 36.8% lower, and a fossil fuel saving ratio of ∼30% is achievable with a solar thermal share of ∼20%. The system integration predicts high efficiency conversion of solar heat and low-energy-penalty CO 2 capture, with the additional advantage that solar heat is at relatively low temperature where its collection is cheaper and

  8. How positive is the feedback between climate change and the carbon cycle?

    International Nuclear Information System (INIS)

    Friedlingstein, P.; Rayner, P.

    2003-01-01

    Future climate change induced by atmospheric emissions of greenhouse gases is believed to have a large impact on the global carbon cycle. Several offline studies focusing either on the marine or on the terrestrial carbon cycle highlighted such potential effects. Two recent online studies, using ocean-atmosphere general circulation models coupled to land and ocean carbon cycle models, investigated in a consistent way the feedback between the climate change and the carbon cycle. These two studies used observed anthropogenic CO 2 emissions for the 1860-1995 period and IPCC scenarios for the 1995-2100 period to force the climate - carbon cycle models. The study from the Hadley Centre group showed a very large positive feedback, atmospheric CO 2 reaching 980 ppmv by 2100 if future climate impacts on the carbon cycle, but only about 700 ppmv if the carbon cycle is included but assumed to be insensitive to the climate change. The IPSL coupled climate - carbon cycle model simulated a much smaller positive feedback: climate impact on the carbon cycle leads by 2100 to an addition of less than 100 ppmv in the atmosphere. Here we perform a detailed feedback analysis to show that such differences are due to two key processes that are still poorly constrained in these coupled models: first Southern Ocean circulation, which primarily controls the geochemical uptake of CO 2 , and second vegetation and soil carbon response to global warming. Our analytical analysis reproduces remarkably the results obtained by the fully coupled models. Also it allows us to identify that, amongst the two processes mentioned above, the latter (the land response to global warming) is the one that essentially explains the differences between the IPSL and the Hadley results

  9. Dual Expander Cycle Rocket Engine with an Intermediate, Closed-cycle Heat Exchanger

    Science.gov (United States)

    Greene, William D. (Inventor)

    2008-01-01

    A dual expander cycle (DEC) rocket engine with an intermediate closed-cycle heat exchanger is provided. A conventional DEC rocket engine has a closed-cycle heat exchanger thermally coupled thereto. The heat exchanger utilizes heat extracted from the engine's fuel circuit to drive the engine's oxidizer turbomachinery.

  10. Ammonia-water Rankine cycle

    International Nuclear Information System (INIS)

    Bo Hanliang; Ma Changwen; Wu Shaorong

    1997-01-01

    On characteristics of heating source and cooling source in nuclear heating reactor cooperation, the authors advance a new kind of power cycle in which a multicomponent mixture as the work fluid, ammonia-water Rankine cycle, describe its running principle, and compare it with steam Rankine cycle in the same situation. The result is that: the new kind of power cycle, ammonia-water Rankine cycle has higher electricity efficiency; it suits for the situation of heating source and cooling source which offered by nuclear heating reactor cooperation. For low temperature heating source, it maybe has a widely application

  11. International Nuclear Fuel Cycle Fact Book

    Energy Technology Data Exchange (ETDEWEB)

    Leigh, I.W.; Patridge, M.D.

    1991-05-01

    As the US Department of Energy (DOE) and DOE contractors have become increasingly involved with other nations in nuclear fuel cycle and waste management cooperative activities, a need has developed for a ready source of information concerning foreign fuel cycle programs, facilities, and personnel. This Fact Book was compiled to meet that need. The information contained in the International Nuclear Fuel Cycle Fact Book has been obtained from many unclassified sources: nuclear trade journals and newsletters; reports of foreign visits and visitors; CEC, IAEA, and OECN/NEA activities reports; not reflect any one single source but frequently represent a consolidation/combination of information.

  12. The thorium fuel cycle in water-moderated reactor systems

    International Nuclear Information System (INIS)

    Critoph, E.

    1977-01-01

    Current interest in the thorium cycle, as an alternative to the uranium cycle, for water-moderated reactors is based on two attractive aspects of its use - the extension of uranium resources, and the related lower sensitivity of energy costs to uranium price. While most of the scientific basis required is already available, some engineering demonstrations are needed to provide better economic data for rational decisions. Thorium and uranium cycles are compared with regard to reactor characteristics and technology, fuel-cycle technology, economic parameters, fuel-cycle costs, and system characteristics. There appear to be no major feasibility problems associated with the use of thorium, although development is required in the areas of fuel testing and fuel management. The use of thorium cycles implies recycling the fuel, and the major uncertainties are in the associated costs. Experience in the design and operation of fuel reprocessing and active-fabrication facilities is required to estimate costs to the accuracy needed for adequately defining the range of conditions economically favourable to thorium cycles. In heavy-water reactors (HWRs) thorium cycles having uranium requirements at equilibrium ranging from zero to a quarter of those for the natural-uranium once-through cycle appear feasible. An ''inventory'' of uranium of between 1 and 2Mg/MW(e) is required for the transition to equilibrium. The cycles with the lowest uranium requirements compete with the others only at high uranium prices. Using thorium in light-water reactors, uranium requirements can be reduced by a factor of between two and three from the once-through uranium cycle. The light-water breeder reactor, promising zero uranium requirements at equilibrium, is being developed. Larger uranium inventories are required than for the HWRs. The lead time, from a decision to use thorium to significant impact on uranium utilization (compared to uranium cycle, recycling plutonium), is some two decades

  13. Study on the supercritical CO2 power cycles for landfill gas firing gas turbine bottoming cycle

    International Nuclear Information System (INIS)

    Kim, Min Seok; Ahn, Yoonhan; Kim, Beomjoo; Lee, Jeong Ik

    2016-01-01

    In this paper, a comparison of nine supercritical carbon dioxide (S-CO 2 ) bottoming power cycles in conjunction with a topping cycle of landfill gas (LFG) fired 5MWe gas turbine is presented. For the comparison purpose, a sensitivity study of the cycle design parameters for nine different cycles was conducted and each cycle thermodynamic performance is evaluated. In addition, the cycle performance evaluation dependency on the compressor inlet temperature variation is performed to investigate how S-CO 2 cycles sensitive to the heat sink temperature variation. Furthermore, the development of new S-CO 2 cycle layouts is reported and the suggested cycles' performances are compared to the existing cycle layouts. It was found that a recompression cycle is not suitable for the bottoming cycle application, but a partial heating cycle has relatively higher net produced work with a simple layout and small number of components. Although a dual heated and flow split cycle has the highest net produced work, it has disadvantages of having numerous components and complex process which requires more sophisticated operational strategies. This study identified that the recuperation process is much more important than the intercooling process to the S-CO 2 cycle design for increasing the thermal efficiency and the net produced work point of view. - Highlights: • Study of nine S-CO 2 power cycle layouts for a small scale landfill gas power generation application. • Development of new S-CO 2 cycle layouts. • Sensitivity analysis of S-CO 2 cycles to evaluate and compare nine cycles' performances.

  14. Recovery from disturbance requires resynchronization of ecosystem nutrient cycles.

    Science.gov (United States)

    Rastetter, E B; Yanai, R D; Thomas, R Q; Vadeboncoeur, M A; Fahey, T J; Fisk, M C; Kwiatkowski, B L; Hamburg, S P

    2013-04-01

    Nitrogen (N) and phosphorus (P) are tightly cycled in most terrestrial ecosystems, with plant uptake more than 10 times higher than the rate of supply from deposition and weathering. This near-total dependence on recycled nutrients and the stoichiometric constraints on resource use by plants and microbes mean that the two cycles have to be synchronized such that the ratio of N:P in plant uptake, litterfall, and net mineralization are nearly the same. Disturbance can disrupt this synchronization if there is a disproportionate loss of one nutrient relative to the other. We model the resynchronization of N and P cycles following harvest of a northern hardwood forest. In our simulations, nutrient loss in the harvest is small relative to postharvest losses. The low N:P ratio of harvest residue results in a preferential release of P and retention of N. The P release is in excess of plant requirements and P is lost from the active ecosystem cycle through secondary mineral formation and leaching early in succession. Because external P inputs are small, the resynchronization of the N and P cycles later in succession is achieved by a commensurate loss of N. Through succession, the ecosystem undergoes alternating periods of N limitation, then P limitation, and eventually co-limitation as the two cycles resynchronize. However, our simulations indicate that the overall rate and extent of recovery is limited by P unless a mechanism exists either to prevent the P loss early in succession (e.g., P sequestration not stoichiometrically constrained by N) or to increase the P supply to the ecosystem later in succession (e.g., biologically enhanced weathering). Our model provides a heuristic perspective from which to assess the resynchronization among tightly cycled nutrients and the effect of that resynchronization on recovery of ecosystems from disturbance.

  15. Heat recovery from Diesel engines: A thermodynamic comparison between Kalina and ORC cycles

    International Nuclear Information System (INIS)

    Bombarda, Paola; Invernizzi, Costante M.; Pietra, Claudio

    2010-01-01

    In the context of heat recovery for electric power generation, Kalina cycle (a thermodynamic cycle using as working fluid a mixture of water and ammonia) and Organic Rankine Cycle (ORC) represent two different eligible technologies. In this work a comparison between the thermodynamic performances of Kalina cycle and an ORC cycle, using hexamethyldisiloxane as working fluid, was conducted for the case of heat recovery from two Diesel engines, each one with an electrical power of 8900 kWe. The maximum net electric power that can be produced exploiting the heat source constituted by the exhaust gases mass flow (35 kg/s for both engines, at 346 deg. C) was calculated for the two thermodynamic cycles. Owing to the relatively low useful power, for the Kalina cycle a relatively simple plant layout was assumed. Supposing reasonable design parameters and a logarithmic mean temperature difference in the heat recovery exchanger of 50 deg. C, a net electric power of 1615 kW and of 1603 kW respectively for the Kalina and for the ORC cycle was calculated. Although the obtained useful powers are actually equal in value, the Kalina cycle requires a very high maximum pressure in order to obtain high thermodynamic performances (in our case, 100 bar against about 10 bar for the ORC cycle). So, the adoption of Kalina cycle, at least for low power level and medium-high temperature thermal sources, seems not to be justified because the gain in performance with respect to a properly optimized ORC is very small and must be obtained with a complicated plant scheme, large surface heat exchangers and particular high pressure resistant and no-corrosion materials.

  16. Effect of cycle coupling-configuration on energy cascade utilization for a new power and cooling cogeneration cycle

    International Nuclear Information System (INIS)

    Jing, Xuye; Zheng, Danxing

    2014-01-01

    Highlights: • A new power and cooling cogeneration cycle was proposed. • The thermophysical properties and the performance of the new cycle were calculated. • Different cycle coupling-configurations were analyzed. • The energy efficiency boosting mechanism of the new cycle was elucidated. - Abstract: To recover mid-low grade heat, a new power/cooling cogeneration cycle was proposed by combining the Kalina cycle and the double-effect ammonia–water absorption refrigeration (DAAR) cycle together, and the equivalent heat-to-power and exergy efficiencies of the cogeneration cycle reached 41.18% and 58.00%, respectively. To determine the effect of cycle coupling-configuration on energy cascade utilization for the new cycle, the cycle coupling-configuration of the Kalina and DAAR cycles were first analyzed, after which the cycle coupling-configuration of the new cycle was analyzed. Analysis results showed that the cycle coupling-configuration of the new cycle enhanced the energy cascade utilization. Furthermore, the energy efficiency boosting mechanism of the new cycle was elucidated

  17. Two distinct modes for propagation of histone PTMs across the cell cycle

    DEFF Research Database (Denmark)

    Alabert, Constance; Barth, Teresa K; Reverón-Gómez, Nazaret

    2015-01-01

    Epigenetic states defined by chromatin can be maintained through mitotic cell division. However, it remains unknown how histone-based information is transmitted. Here we combine nascent chromatin capture (NCC) and triple-SILAC (stable isotope labeling with amino acids in cell culture) labeling...... to track histone modifications and histone variants during DNA replication and across the cell cycle. We show that post-translational modifications (PTMs) are transmitted with parental histones to newly replicated DNA. Di- and trimethylation marks are diluted twofold upon DNA replication, as a consequence...... of new histone deposition. Importantly, within one cell cycle, all PTMs are restored. In general, new histones are modified to mirror the parental histones. However, H3K9 trimethylation (H3K9me3) and H3K27me3 are propagated by continuous modification of parental and new histones because the establishment...

  18. The Salmon Louse Lepeophtheirus salmonis (Copepoda: Caligidae life cycle has only two Chalimus stages.

    Directory of Open Access Journals (Sweden)

    Lars A Hamre

    Full Text Available Each year the salmon louse (Lepeophtheirussalmonis Krøyer, 1838 causes multi-million dollar commercial losses to the salmon farming industry world-wide, and strict lice control regimes have been put in place to reduce the release of salmon louse larvae from aquaculture facilities into the environment. For half a century, the Lepeophtheirus life cycle has been regarded as the only copepod life cycle including 8 post-nauplius instars as confirmed in four different species, including L. salmonis. Here we prove that the accepted life cycle of the salmon louse is wrong. By observations of chalimus larvae molting in incubators and by morphometric cluster analysis, we show that there are only two chalimus instars: chalimus 1 (comprising the former chalimus I and II stages which are not separated by a molt and chalimus 2 (the former chalimus III and IV stages which are not separated by a molt. Consequently the salmon louse life cycle has only six post-nauplius instars, as in other genera of caligid sea lice and copepods in general. These findings are of fundamental importance in experimental studies as well as for interpretation of salmon louse biology and for control and management of this economically important parasite.

  19. Episode cycles with increasing recurrences in first-episode bipolar-I disorder patients.

    Science.gov (United States)

    Baldessarini, R J; Salvatore, P; Khalsa, H-M K; Imaz-Etxeberria, H; Gonzalez-Pinto, A; Tohen, M

    2012-01-01

    Preliminary review of a century of studies of the course of manic-depressive syndromes produced 40 reports, of which approximately one-third report evidence of shortening wellness intervals or cycle-lengths with more recurrences, and two-thirds did not. We evaluated inter-episode intervals (cycle-length) in 128 clinically-treated, DSM-IV bipolar-I disorder patients followed prospectively and systematically over 5.7 years, with 6.5 episodes/person. As expected, cycle-length varied inversely with total cycle-count/person; however, multivariate linear regression found only longer initial hospitalization and fewer total cycles to be associated with cycle-length, whereas cycle-number (1, 2, 3, etc.), sex, intake-age, and first-episode polarity were not. Regression of within-subject cycle-length versus cycle-number yielded individual slope-functions with pseudo-random distribution (28% fell within ±1 month/cycle of the null [zero-slope]). Mean duration of early and late euthymic intervals (cycles 2 vs. 5) in patients with matched recurrence-counts was nearly identical. The course of bipolar-I disorder from onset was largely random or chaotic over nearly 6 years from onset. Only a minority of patients showed either cycle-acceleration or slowing, without changes in wellness intervals. The findings may be influenced by treatment-effects, but seem to indicate that most current bipolar-I disorder patients are unlikely to show progressive shortening of recurrence-cycles. Copyright © 2011 Elsevier B.V. All rights reserved.

  20. Nuclear fuel cycle system analysis

    International Nuclear Information System (INIS)

    Ko, W. I.; Kwon, E. H.; Kim, S. G.; Park, B. H.; Song, K. C.; Song, D. Y.; Lee, H. H.; Chang, H. L.; Jeong, C. J.

    2012-04-01

    The nuclear fuel cycle system analysis method has been designed and established for an integrated nuclear fuel cycle system assessment by analyzing various methodologies. The economics, PR(Proliferation Resistance) and environmental impact evaluation of the fuel cycle system were performed using improved DB, and finally the best fuel cycle option which is applicable in Korea was derived. In addition, this research is helped to increase the national credibility and transparency for PR with developing and fulfilling PR enhancement program. The detailed contents of the work are as follows: 1)Establish and improve the DB for nuclear fuel cycle system analysis 2)Development of the analysis model for nuclear fuel cycle 3)Preliminary study for nuclear fuel cycle analysis 4)Development of overall evaluation model of nuclear fuel cycle system 5)Overall evaluation of nuclear fuel cycle system 6)Evaluate the PR for nuclear fuel cycle system and derive the enhancement method 7)Derive and fulfill of nuclear transparency enhancement method The optimum fuel cycle option which is economical and applicable to domestic situation was derived in this research. It would be a basis for establishment of the long-term strategy for nuclear fuel cycle. This work contributes for guaranteeing the technical, economical validity of the optimal fuel cycle option. Deriving and fulfillment of the method for enhancing nuclear transparency will also contribute to renewing the ROK-U.S Atomic Energy Agreement in 2014

  1. Heteroclinic cycles in the repressilator model

    International Nuclear Information System (INIS)

    Kuznetsov, A.; Afraimovich, V.

    2012-01-01

    Highlights: ► We conduct analysis at infinity in the phase space of the repressilator model. ► We study two models with the original linear and a new saturable degradation terms. ► We link the evolution of an oscillatory solution with a heteroclinic cycle. ► The transition studied here presents a new bifurcation scenario. - Abstract: A repressilator is a synthetic regulatory network that produces self-sustained oscillations. We analyze the evolution of the oscillatory solution in the repressilator model. We have established a connection between the evolution of the oscillatory solution and formation of a heteroclinic cycle at infinity. The convergence of the limit cycle to the heteroclinic cycle occurs very differently compared to the well-studied cases. The transition studied here presents a new bifurcation scenario.

  2. Optimum heat power cycles for specified boundary conditions

    International Nuclear Information System (INIS)

    Ibrahim, O.M.; Klein, S.A.; Mitchell, J.W.

    1991-01-01

    In this paper optimization of the power output of Carnot and closed Brayton cycles is considered for both finite and infinite thermal capacitance rates of the external fluid streams. The method of Lagrange multipliers is used to solve for working fluid temperatures that yield maximum power. Analytical expressions for the maximum power and the cycle efficiency at maximum power are obtained. A comparison of the maximum power from the two cycles for the same boundary conditions, i.e., the same heat source/sink inlet temperatures, thermal capacitance rates, and heat exchanger conductances, shows that the Brayton cycle can produce more power than the Carnot cycle. This comparison illustrates that cycles exist that can produce more power than the Carnot cycle. The optimum heat power cycle, which will provide the upper limit of power obtained from any thermodynamic cycle for specified boundary conditions and heat exchanger conductances is considered. The optimum heat power cycle is identified by optimizing the sum of the power output from a sequence of Carnot cycles. The shape of the optimum heat power cycle, the power output, and corresponding efficiency are presented. The efficiency at maximum power of all cycles investigated in this study is found to be equal to (or well approximated by) η = 1 - sq. root T L.in /φT H.in where φ is a factor relating the entropy changes during heat rejection and heat addition

  3. Driving and engine cycles

    CERN Document Server

    Giakoumis, Evangelos G

    2017-01-01

    This book presents in detail the most important driving and engine cycles used for the certification and testing of new vehicles and engines around the world. It covers chassis and engine-dynamometer cycles for passenger cars, light-duty vans, heavy-duty engines, non-road engines and motorcycles, offering detailed historical information and critical review. The book also provides detailed examples from SI and diesel engines and vehicles operating during various cycles, with a focus on how the engine behaves during transients and how this is reflected in emitted pollutants, CO2 and after-treatment systems operation. It describes the measurement methods for the testing of new vehicles and essential information on the procedure for creating a driving cycle. Lastly, it presents detailed technical specifications on the most important chassis-dynamometer cycles around the world, together with a direct comparison of those cycles.

  4. Role of expanders in helium liquefaction cycles: Parametric studies using Collins cycle

    International Nuclear Information System (INIS)

    Thomas, Rijo Jacob; Ghosh, Parthasarathi; Chowdhury, Kanchan

    2011-01-01

    Large scale helium liquefaction/refrigeration plant is a key subsystem of fusion devices. Performance of these plants is dependent on a number of geometric and operating parameters of its constituting components such as compressors, heat exchangers, expanders, valves, etc. Expander has been chosen as the subject matter of analyses in the present study. As the sensible cold of helium vapor is lost in liquefiers, the expanders in liquefaction cycles have to provide more refrigeration than those in refrigeration cycles. The expander parameters such as rate of mass flow, operating pressure, inlet temperature, etc. are inter-dependent, and hence, it is difficult to predict the system behavior with variation of a particular parameter. This necessitates the use of process simulators. Parametric studies have been performed on Collins helium liquefaction cycle using Aspen HYSYS. Collins cycle has all the basic characteristics of a large-scale helium liquefier and the results of this study may be extrapolated to understand the behavior of large scale helium liquefiers. The study shows that the maximum liquid production is obtained when 80% of the compressor flow is diverted through the expanders and it is equally distributed between the two expanders. The relationships between the liquid production and the isentropic efficiency of expanders are almost linear and both the higher and lower temperature expanders exhibit similar trends.

  5. Role of expanders in helium liquefaction cycles: Parametric studies using Collins cycle

    Energy Technology Data Exchange (ETDEWEB)

    Thomas, Rijo Jacob, E-mail: rijojthomas@gmail.com [Cryogenic Engineering Centre, Indian Institute of Technology, Kharagpur, West Bengal 721302 (India); Ghosh, Parthasarathi; Chowdhury, Kanchan [Cryogenic Engineering Centre, Indian Institute of Technology, Kharagpur, West Bengal 721302 (India)

    2011-06-15

    Large scale helium liquefaction/refrigeration plant is a key subsystem of fusion devices. Performance of these plants is dependent on a number of geometric and operating parameters of its constituting components such as compressors, heat exchangers, expanders, valves, etc. Expander has been chosen as the subject matter of analyses in the present study. As the sensible cold of helium vapor is lost in liquefiers, the expanders in liquefaction cycles have to provide more refrigeration than those in refrigeration cycles. The expander parameters such as rate of mass flow, operating pressure, inlet temperature, etc. are inter-dependent, and hence, it is difficult to predict the system behavior with variation of a particular parameter. This necessitates the use of process simulators. Parametric studies have been performed on Collins helium liquefaction cycle using Aspen HYSYS. Collins cycle has all the basic characteristics of a large-scale helium liquefier and the results of this study may be extrapolated to understand the behavior of large scale helium liquefiers. The study shows that the maximum liquid production is obtained when 80% of the compressor flow is diverted through the expanders and it is equally distributed between the two expanders. The relationships between the liquid production and the isentropic efficiency of expanders are almost linear and both the higher and lower temperature expanders exhibit similar trends.

  6. Fatigue of Austempered Ductile Iron with Two Strength Grades in Very High Cycle Regime

    Science.gov (United States)

    Zhang, Jiwang; Li, Wei; Song, Qingpeng; Zhang, Ning; Lu, Liantao

    2016-03-01

    In this study, Austempered ductile irons (ADIs) with two different strength grades were produced and the fatigue properties were measured at 109 cycles. The results show that the S-N curves give a typical step-wise shape and there is no fatigue limit in the very high cycle fatigue regime. The two grades ADI have the similar fracture behaviors and fatigue failure can initiate from defects at specimen surface and subsurface zone. On the fracture surfaces of some specimens, the `granular-bright-facet' area with rich carbon distribution is observed in the vicinity of the defect. The microstructure affects the crack behaviors at the early propagation stage. The ADI with upper and lower bainite shows higher fatigue strength compared with the ADI with coarse upper bainite.

  7. Nonlinear solar cycle forecasting: theory and perspectives

    Directory of Open Access Journals (Sweden)

    A. L. Baranovski

    2008-02-01

    Full Text Available In this paper we develop a modern approach to solar cycle forecasting, based on the mathematical theory of nonlinear dynamics. We start from the design of a static curve fitting model for the experimental yearly sunspot number series, over a time scale of 306 years, starting from year 1700 and we establish a least-squares optimal pulse shape of a solar cycle. The cycle-to-cycle evolution of the parameters of the cycle shape displays different patterns, such as a Gleissberg cycle and a strong anomaly in the cycle evolution during the Dalton minimum. In a second step, we extract a chaotic mapping for the successive values of one of the key model parameters – the rate of the exponential growth-decrease of the solar activity during the n-th cycle. We examine piece-wise linear techniques for the approximation of the derived mapping and we provide its probabilistic analysis: calculation of the invariant distribution and autocorrelation function. We find analytical relationships for the sunspot maxima and minima, as well as their occurrence times, as functions of chaotic values of the above parameter. Based on a Lyapunov spectrum analysis of the embedded mapping, we finally establish a horizon of predictability for the method, which allows us to give the most probable forecasting of the upcoming solar cycle 24, with an expected peak height of 93±21 occurring in 2011/2012.

  8. Measuring risky adolescent cycling behaviour.

    Science.gov (United States)

    Feenstra, Hans; Ruiter, Robert A C; Schepers, Jan; Peters, Gjalt-Jorn; Kok, Gerjo

    2011-09-01

    Adolescents are at a greater risk of being involved in traffic accidents than most other age groups, even before they start driving cars. This article aims to determine the factor structure of a self-report questionnaire measuring adolescent risky cycling behaviour, the ACBQ (Adolescent Cycling Behaviour Questionnaire). The questionnaire's structure was based on the widely used Driver Behaviour Questionnaire (DBQ). A sample of secondary school students (N = 1749; age range: 13-18 years) filled out the questionnaire. Factor analysis revealed a three-factor structure underlying the questionnaire, which was confirmed on two equally large portions of the entire sample. These three underlying factors were identified as errors, common violations and exceptional violations. The ACBQ is a useful instrument for measuring adolescents' risky cycling behaviour.

  9. The heat engine cycle, the heat removal cycle, and ergonomics of the control room displays

    International Nuclear Information System (INIS)

    Beltracchi, L.

    1986-01-01

    This paper discusses and illustrates the ergonomics of an integrated display, which will allow operators to monitor the heat engine cycle during normal operation of the plant, and the heat removal cycle during emergency operation of the plant. A computer-based iconic display is discussed as an overview to monitor these cycles. Specific emphasis is placed upon the process variables and process functions within each cycle, and the action of control systems and engineered safeguard systems within each cycle. This paper contains examples of display formats for the heat engine cycle and the heat removal cycle in a pressurized water reactor

  10. Novel combined cycle configurations for propane pre-cooled mixed refrigerant (APCI) natural gas liquefaction cycle

    International Nuclear Information System (INIS)

    Mortazavi, Amir; Alabdulkarem, Abdullah; Hwang, Yunho; Radermacher, Reinhard

    2014-01-01

    Highlights: • 10 New LNG plants driver cycle enhancement configurations were developed. • All the 14 enhancement options design variables were optimized to demonstrate their energy saving potentials. • The best driver cycle enhancement option improved the driver cycle energy efficiency by 38%. • The effects of technological advancements on the performances of the enhancement options were studied. - Abstract: A significant amount of energy is required for natural gas liquefaction. Due to the production scale of LNG plants, they consume an intensive amount of energy. Consequently, any enhancement to the energy efficiency of LNG plants will result in a considerable reduction in natural gas consumption and CO 2 emission. Compressor drivers are the main energy consumer in the LNG plants. In this paper, 14 different driver cycle enhancement options were considered. A number of these options have not been proposed for the LNG plants. The new driver cycle development was performed by analyzing and optimizing the design variables of four conventional driver cycle enhancement options. The optimization results were used to develop more efficient cycles through mitigating the active constrains and driver cycle innovations. Based on the current available technologies five of our newly developed driver cycle configurations have higher efficiency than the most efficient existing conventional driver cycle. The best developed driver cycle enhancement option improved the base driver cycle energy efficiency by 38%. The effects of technological advancement on the performances of the all driver cycle enhancement options were also considered

  11. Identifying and Analyzing Strong Components of an Industrial Network Based on Cycle Degree

    Directory of Open Access Journals (Sweden)

    Zhiying Zhang

    2016-01-01

    Full Text Available In the era of big data and cloud computing, data research focuses not only on describing the individual characteristics but also on depicting the relationships among individuals. Studying dependence and constraint relationships among industries has aroused significant interest in the academic field. From the network perspective, this paper tries to analyze industrial relational structures based on cycle degree. The cycle degree of a vertex, that is, the number of cycles through a vertex in an industrial network, can describe the roles of the vertices of strong components in industrial circulation. In most cases, different vertices in a strong component have different cycle degrees, and the one with a larger cycle degree plays more important roles. However, the concept of cycle degree does not involve the lengths of the cycles, which are also important for circulations. The more indirect the relationship between two industries is, the weaker it is. In order to analyze strong components thoroughly, this paper proposes the concept of circular centrality taking into consideration the influence by two factors: the lengths and the numbers of cycles through a vertex. Exemplification indicates that a profound analysis of strong components in an industrial network can reveal the features of an economy.

  12. Finnish and Swedish business cycles in a global context

    DEFF Research Database (Denmark)

    Bergman, Ulf Michael

    2008-01-01

    This paper evaluates the decisions made by the Finnish government to join EMU and the Swedish government not to join EMU in the early 1990s. Focusing on the characteristics of business cycles during the postwar period, we find that output fluctuations in Sweden and Finland are correlated to two...... measures of the international business cycle, a European and a non-European cycle. The Finnish cycle has become more synchronized to the European cycle but less synchronized to the non-EU cycle after 1999. For Sweden we find the opposite result. The decision by the Finnish government to join EMU...

  13. Cycles within micronets and at the gel point

    DEFF Research Database (Denmark)

    Armitage, David H.; Cameron, Colin; Fawcett, Allan H.

    2000-01-01

    three-dimensional space. Not only may cycles form in competition with branching growth, but if the statistics require it, segments of one cycle may be shared with those of any number of others, as Houwink indicated in 1935. After a small number of simple cycle-containing micronet molecules...... zero, when m≅24. The periodic boundaries of the model were not large enough to provide the exact behavior of the cycle number as m becomes larger, but an explosion is certainly indicated by k becoming negative. A resilient product is predicted at the gel point....

  14. General performance characteristics of an irreversible ferromagnetic Stirling refrigeration cycle

    International Nuclear Information System (INIS)

    Lin, G.; Tegus, O.; Zhang, L.; Brueck, E.

    2004-01-01

    A new magnetic-refrigeration-cycle model using ferromagnetic materials as a cyclic working substance is set up, in which finite-rate heat transfer, heat leak and regeneration time are taken into account. On the basis of the thermodynamic properties of a ferromagnetic material, the general performance characteristics of the ferromagnetic Stirling refrigeration cycle are investigated and the effects of some key irreversibilities on the performance of the cycle are revealed. By using the optimal-control theory, the optimal relation between the coefficient of performance and the cooling rate is derived and some important performance bounds, e.g., the maximum cooling rate, the maximum coefficient of performance, are determined. Moreover, the optimal operating regions for cooling rate, coefficient of performance and the optimal operating temperatures of a cyclic working substance in the two heat-transfer processes are obtained. Furthermore, the influences of magnetization and magnetic field on the performance characteristics of the cycle are discussed. The results obtained here have general significance and can be deduced to the related ones of the Stirling refrigeration cycle using paramagnetic salt as a cyclic working substance

  15. Chords in longest cycles

    DEFF Research Database (Denmark)

    Thomassen, Carsten

    2017-01-01

    If a graph G is 3-connected and has minimum degree at least 4, then some longest cycle in G has a chord. If G is 2-connected and cubic, then every longest cycle in G has a chord.......If a graph G is 3-connected and has minimum degree at least 4, then some longest cycle in G has a chord. If G is 2-connected and cubic, then every longest cycle in G has a chord....

  16. Temporal fluxomics reveals oscillations in TCA cycle flux throughout the mammalian cell cycle.

    Science.gov (United States)

    Ahn, Eunyong; Kumar, Praveen; Mukha, Dzmitry; Tzur, Amit; Shlomi, Tomer

    2017-11-06

    Cellular metabolic demands change throughout the cell cycle. Nevertheless, a characterization of how metabolic fluxes adapt to the changing demands throughout the cell cycle is lacking. Here, we developed a temporal-fluxomics approach to derive a comprehensive and quantitative view of alterations in metabolic fluxes throughout the mammalian cell cycle. This is achieved by combining pulse-chase LC-MS-based isotope tracing in synchronized cell populations with computational deconvolution and metabolic flux modeling. We find that TCA cycle fluxes are rewired as cells progress through the cell cycle with complementary oscillations of glucose versus glutamine-derived fluxes: Oxidation of glucose-derived flux peaks in late G1 phase, while oxidative and reductive glutamine metabolism dominates S phase. These complementary flux oscillations maintain a constant production rate of reducing equivalents and oxidative phosphorylation flux throughout the cell cycle. The shift from glucose to glutamine oxidation in S phase plays an important role in cell cycle progression and cell proliferation. © 2017 The Authors. Published under the terms of the CC BY 4.0 license.

  17. Cycle analysis of MCFC/gas turbine system

    Directory of Open Access Journals (Sweden)

    Musa Abdullatif

    2017-01-01

    Full Text Available High temperature fuel cells such as the solid oxide fuel cell (SOFC and the molten carbonate fuel cell (MCFC are considered extremely suitable for electrical power plant application. The molten carbonate fuel cell (MCFC performances is evaluated using validated model for the internally reformed (IR fuel cell. This model is integrated in Aspen Plus™. Therefore, several MCFC/Gas Turbine systems are introduced and investigated. One of this a new cycle is called a heat recovery (HR cycle. In the HR cycle, a regenerator is used to preheat water by outlet air compressor. So the waste heat of the outlet air compressor and the exhaust gases of turbine are recovered and used to produce steam. This steam is injected in the gas turbine, resulting in a high specific power and a high thermal efficiency. The cycles are simulated in order to evaluate and compare their performances. Moreover, the effects of an important parameters such as the ambient air temperature on the cycle performance are evaluated. The simulation results show that the HR cycle has high efficiency.

  18. Cycle analysis of MCFC/gas turbine system

    Science.gov (United States)

    Musa, Abdullatif; Alaktiwi, Abdulsalam; Talbi, Mosbah

    2017-11-01

    High temperature fuel cells such as the solid oxide fuel cell (SOFC) and the molten carbonate fuel cell (MCFC) are considered extremely suitable for electrical power plant application. The molten carbonate fuel cell (MCFC) performances is evaluated using validated model for the internally reformed (IR) fuel cell. This model is integrated in Aspen Plus™. Therefore, several MCFC/Gas Turbine systems are introduced and investigated. One of this a new cycle is called a heat recovery (HR) cycle. In the HR cycle, a regenerator is used to preheat water by outlet air compressor. So the waste heat of the outlet air compressor and the exhaust gases of turbine are recovered and used to produce steam. This steam is injected in the gas turbine, resulting in a high specific power and a high thermal efficiency. The cycles are simulated in order to evaluate and compare their performances. Moreover, the effects of an important parameters such as the ambient air temperature on the cycle performance are evaluated. The simulation results show that the HR cycle has high efficiency.

  19. A novel split cycle internal combustion engine with integral waste heat recovery

    International Nuclear Information System (INIS)

    Dong, Guangyu; Morgan, Robert; Heikal, Morgan

    2015-01-01

    Highlights: • A novel engine thermodynamic cycle is proposed. • Theoretical analysis is applied to identify the key parameters of the thermodynamic cycle. • The key stages of the split cycle are analysed via one-dimensional modelling work. • The effecting mechanism of the split cycle efficiency is analysed. - Abstract: To achieve a step improvement in engine efficiency, a novel split cycle engine concept is proposed. The engine has separate compression and combustion cylinders and waste heat is recovered between the two. Quasi-isothermal compression of the charge air is realised in the compression cylinder while isobaric combustion of the air/fuel mixture is achieved in the combustion cylinder. Exhaust heat recovery between the compression and combustion chamber enables highly efficient recovery of waste heat within the cycle. Based on cycle analysis and a one-dimensional engine model, the fundamentals and the performance of the split thermodynamic cycle is estimated. Compared to conventional engines, the compression work can be significantly reduced through the injection of a controlled quantity of water in the compression cylinder, lowering the gas temperature during compression. Thermal energy can then be effectively recovered from the engine exhaust in a recuperator between the cooled compressor cylinder discharge air and the exhaust gas. The resulting hot high pressure air is then injected into a combustor cylinder and mixed with fuel, where near isobaric combustion leads to a low combustion temperature and reduced heat transferred from the cylinder wall. Detailed cycle simulation indicates a 32% efficiency improvement can be expected compared to the conventional diesel engines.

  20. Applying life cycle management of colombian cocoa production

    Directory of Open Access Journals (Sweden)

    Oscar Orlando Ortiz-R

    2014-03-01

    Full Text Available The present research aims to evaluate the usefulness of the application of Life Cycle Management in the agricultural sector focusing on the environmental and socio-economic aspects of decision making in the Colombian cocoa production. Such appraisal is based on the application of two methodological tools: Life Cycle Assessment, which considers environmental impacts throughout the life cycle of the cocoa production system, and Taguchi Loss Function, which measures the economic impact of a process' deviation from production targets. Results show that appropriate improvements in farming practices and supply consumption can enhance decision-making in the agricultural cocoa sector towards sustainability. In terms of agri-business purposes, such qualitative shift allows not only meeting consumer demands for environmentally friendly products, but also increasing the productivity and competitiveness of cocoa production, all of which has helped Life Cycle Management gain global acceptance. Since farmers have an important role in improving social and economic indicators at the national level, more attention should be paid to the upgrading of their cropping practices. Finally, one fundamental aspect of national cocoa production is the institutional and governmental support available for farmers in face of socio-economic or technological needs.

  1. Nitrogen cycling under alternate wetting and drying cycles in Arkansas rice

    Science.gov (United States)

    Alternate wetting and drying (AWD) cycles offer potential savings in water use for paddy rice production while reducing both greenhouse gas emissions and lowering grain arsenic content. In a three-year (2011-2013) field study near Stuttgart, AR, one-third of a field previously grown to soybean was b...

  2. Back end of the fuel cycle

    International Nuclear Information System (INIS)

    Wolfe, B.; Lambert, R.W.

    1975-01-01

    At present, that portion of the nuclear fuel cycle involving reprocessing, waste management, and mixed-oxide fuel fabrication is in an unsettled state. Government regulatory requirements with respect to all aspects of the back end of the fuel cycle are still being formulated, and there is little positive experience on the operation of commercial reprocessing or mixed-oxide fabrication plants. In view of this unsettled situation, it will be difficult to meet the reprocessing and mixed-oxide fabrication needs of the next decade in the pattern previously anticipated. The costs in the back end of the fuel cycle are much higher than had been anticipated several years ago, a situation similar to that of almost all large endeavors in this country. On the other hand, the added costs are small relative to total power costs and do not affect the economic advantage of nuclear power as compared to other power sources. A rough economic analysis indicates that the question for the back end of the fuel cycle has changed from one of optimizing profitability to one of determining the most economic disposition of spent fuel. Long-term spent fuel storage is a practical and economically acceptable way to provide time for determining a sound course of action for the back end of the fuel cycle. Indeed, if one could count on a breeder economy before the end of the century, one possible course of action is to store light-water fuel until the plutonium can be used in breeders. However, for philosophical as well as practical reasons, it is important that the uncertainties in the course of action should be resolved as quickly as possible. Long-term storage should not be an excuse to delay resolution of the basic questions. (U.S.)

  3. Alternative fuel cycles

    International Nuclear Information System (INIS)

    Penn, W.J.

    1979-05-01

    Uranium resource utilization and economic considerations provide incentives to study alternative fuel cycles as future options to the PHWR natural uranium cycle. Preliminary studies to define the most favourable alternatives and their possible introduction dates are discussed. The important and uncertain components which influence option selection are reviewed, including nuclear capacity growth, uranium availability and demand, economic potential, and required technological developments. Finally, a summary of Ontario Hydro's program to further assess cycle selection and define development needs is given. (auth)

  4. Comparative simulation of Stirling and Sibling cycle cryocoolers with two codes

    International Nuclear Information System (INIS)

    Mitchell, M.P.; Wilson, K.J.; Bauwens, L.

    1989-01-01

    The authors present a comparative analysis of Stirling and Sibling Cycle cryocoolers conducted with two different computer simulation codes. One code (CRYOWEISS) performs an initial analysis on the assumption of isothermal conditions in the machines and adjusts that result with decoupled loss calculations. The other code (MS*2) models fluid flows and heat transfers more realistically but ignores significant loss mechanisms, including flow friction and heat conduction through the metal of the machines. Surprisingly, MS*2 is less optimistic about performance of all machines even though it ignores losses that are modelled by CRYOWEISS. Comparison between constant-bore Stirling and Sibling machines shows that their performance is generally comparable over a range of temperatures, pressures and operating speeds. No machine was consistently superior or inferior according to both codes over the whole range of conditions studied

  5. Fuel cycles using adulterated plutonium

    International Nuclear Information System (INIS)

    Brooksbank, R.E.; Bigelow, J.E.; Campbell, D.O.; Kitts, F.G.; Lindauer, R.B.

    1978-01-01

    Adjustments in the U-Pu fuel cycle necessitated by decisions made to improve the nonproliferation objectives of the US are examined. The uranium-based fuel cycle, using bred plutonium to provide the fissile enrichment, is the fuel system with the highest degree of commercial development at the present time. However, because purified plutonium can be used in weapons, this fuel cycle is potentially vulnerable to diversion of that plutonium. It does appear that there are technologically sound ways in which the plutonium might be adulterated by admixture with 238 U and/or radioisotopes, and maintained in that state throughout the fuel cycle, so that the likelihood of a successful diversion is small. Adulteration of the plutonium in this manner would have relatively little effect on the operations of existing or planned reactors. Studies now in progress should show within a year or two whether the less expensive coprocessing scheme would provide adequate protection (coupled perhaps with elaborate conventional safeguards procedures) or if the more expensive spiked fuel cycle is needed as in the proposed civex pocess. If the latter is the case, it will be further necessary to determine the optimum spiking level, which could vary as much as a factor of a billion. A very basic question hangs on these determinations: What is to be the nature of the recycle fuel fabrication facilities. If the hot, fully remote fuel fabrication is required, then a great deal of further development work will be required to make the full cycle fully commercial

  6. Serum uric acid in relation to endogenous reproductive hormones during the menstrual cycle: findings from the BioCycle study

    Science.gov (United States)

    Mumford, Sunni L.; Dasharathy, Sonya S.; Pollack, Anna Z.; Perkins, Neil J.; Mattison, Donald R.; Cole, Stephen R.; Wactawski-Wende, Jean; Schisterman, Enrique F.

    2013-01-01

    STUDY QUESTION Do uric acid levels across the menstrual cycle show associations with endogenous estradiol (E2) and reproductive hormone concentrations in regularly menstruating women? SUMMARY ANSWER Mean uric acid concentrations were highest during the follicular phase, and were inversely associated with E2 and progesterone, and positively associated with FSH. WHAT IS KNOWN ALREADY E2 may decrease serum levels of uric acid in post-menopausal women; however, the interplay between endogenous reproductive hormones and uric acid levels among regularly menstruating women has not been elucidated. STUDY DESIGN, SIZE, DURATION The BioCycle study was a prospective cohort study conducted at the University at Buffalo research centre from 2005 to 2007, which followed healthy women for one (n = 9) or 2 (n = 250) menstrual cycle(s). PARTICIPANTS/MATERIALS, SETTING, METHODS Participants were healthy women aged 18–44 years. Hormones and uric acid were measured in serum eight times each cycle for up to two cycles. Marginal structural models with inverse probability of exposure weights were used to evaluate the associations between endogenous hormones and uric acid concentrations. MAIN RESULTS AND THE ROLE OF CHANCE Uric acid levels were observed to vary across the menstrual cycle, with the lowest levels observed during the luteal phase. Every log-unit increase in E2 was associated with a decrease in uric acid of 1.1% (β = −0.011; 95% confidence interval (CI): −0.019, −0.004; persistent-effects model), and for every log-unit increase in progesterone, uric acid decreased by ∼0.8% (β = −0.008; 95% CI: −0.012, −0.004; persistent-effects model). FSH was positively associated with uric acid concentrations, such that each log-unit increase was associated with a 1.6% increase in uric acid (β = 0.016; 95% CI: 0.005, 0.026; persistent-effects model). Progesterone and FSH were also associated with uric acid levels in acute-effects models. Of 509 cycles, 42 were anovulatory

  7. The safety of the nuclear fuel cycle

    International Nuclear Information System (INIS)

    2005-01-01

    The procurement and preparation of fuel for nuclear power reactors, followed by its recovery, processing and management subsequent to reactor discharge, are frequently referred to as the ''front end'' and ''back end'' of the nuclear fuel cycle. The facilities associated with these activities have an extensive and well-documented safety record accumulated over the past 50 years by technical experts and safety authorities. This information has enabled an in-depth analysis of the complete fuel cycle. Preceded by two previous editions in 1981 and 1993, this new edition of the Safety of the Nuclear Fuel Cycle represents the most up-to-date analysis of the safety aspects of the nuclear fuel cycle. It will be of considerable interest to nuclear safety experts, but also to those wishing to acquire extensive information about the fuel cycle more generally. (author)

  8. The safety of the nuclear fuel cycle

    International Nuclear Information System (INIS)

    2005-10-01

    The procurement and preparation of fuel for nuclear power reactors, followed by its recovery, processing and management subsequent to reactor discharge, are frequently referred to as the 'front end' and 'back end' of the nuclear fuel cycle. The facilities associated with these activities have an extensive and well-documented safety record accumulated over the past 50 years by technical experts and safety authorities. This information has enabled an in-depth analysis of the complete fuel cycle. Preceded by two previous editions in 1981 and 1993, this new edition of The Safety of the Nuclear Fuel Cycle represents the most up-to-date analysis of the safety aspects of the nuclear fuel cycle. It will be of considerable interest to nuclear safety experts, but also to those wishing to acquire extensive information about the fuel cycle more generally. (author)

  9. An Ethnography of the Navajo Reproductive Cycle.

    Science.gov (United States)

    Wright, Anne

    1982-01-01

    Describes the reproductive cycle (menarche, menstrual cycle, fertility and contraceptive use, and menopause) as experienced by two groups of contemporary Navajo women. Eighty Navajo women, 40 traditional and 40 acculturated, participated in the 1978 research project which focused on influences of menopause. (ERB)

  10. Educational Business Cycles

    DEFF Research Database (Denmark)

    Tepe, Markus; Vanhuysse, Pieter

    Strong institutional constraints and better-informed voters may lead re-election seeking incumbents to shift the use of political business cycle mechanisms away from monetary and fiscal policy towards other policy domains that are more easily manipulable, targetable, and timeable. We investigate...... teacher employment patterns at the state level in Germany and find strong evidence of cycling mechanisms, in the form of electioneering and honeymooning. Against a backdrop of a continuously shrinking total teachers' pool, German state-level incumbents accelerate the hiring of new teachers during election...... periods and partly reverse this during politically safer points in the electoral cycle. Cycles are mediated by issue salience: heightened attention to German public schooling after the notorious PISA-2000 tests further strengthens the manipulation of new teacher hiring for electoral purposes....

  11. Educational Business Cycles

    DEFF Research Database (Denmark)

    Tepe, Markus; Vanhuysse, Pieter

    2009-01-01

    Strong institutional constraints and better-informed voters may lead re-election seeking incumbents to shift the use of political business cycle mechanisms away from monetary and fiscal policy towards other policy domains that are more easily manipulable, targetable, and timeable. We investigate...... teacher employment patterns at the state level in Germany and find strong evidence of cycling mechanisms, in the form of electioneering and honeymooning. Against a backdrop of a continuously shrinking total teachers' pool, German state-level incumbents accelerate the hiring of new teachers during election...... periods and partly reverse this during politically safer points in the electoral cycle. Cycles are mediated by issue salience: heightened attention to German public schooling after the notorious PISA-2000 tests further strengthens the manipulation of new teacher hiring for electoral purposes....

  12. Performance research on modified KCS (Kalina cycle system) 11 without throttle valve

    International Nuclear Information System (INIS)

    He, Jiacheng; Liu, Chao; Xu, Xiaoxiao; Li, Yourong; Wu, Shuangying; Xu, Jinliang

    2014-01-01

    Two modified systems based on a KCS (Kalina cycle system) 11 with a two-phase expander to substitute a throttle valve are proposed. The two-phase expander is located between the regenerator and the absorber in the B-modified cycle and between the separator and the regenerator in the C-modified cycle. A thermodynamic performance analysis of both the original KCS 11 and the modified systems is carried out. The optimization of two key parameters (the concentration of working fluid and the temperature of cooling water) is also conducted. It is shown that the two modified cycles have different performance under the investigated conditions. Results also indicate that the C-modified cycle can obtain better thermodynamic effect than the B-modified cycle. The temperature of cooling water plays an important role in improving the system performance. When the cooling water temperature drops from 303 K to 278 K, the C-modified cycle thermal efficiency can be improved by 27%. - Highlights: • Throttling valve is replaced by a two-phase expander to recover the expansion work. • Thermodynamic performance of two modified cycle systems is very different. • The maximum increase of work output by C-modified cycle compared with KCS (Kalina cycle system) 11 is 9.4%. • The ranges of ammonia content of B-modified cycle are rather larger

  13. Termination of cycle rewriting

    NARCIS (Netherlands)

    Zantema, H.; König, B.; Bruggink, H.J.S.; Dowek, G.

    2014-01-01

    String rewriting can not only be applied on strings, but also on cycles and even on general graphs. In this paper we investigate termination of string rewriting applied on cycles, shortly denoted as cycle rewriting, which is a strictly stronger requirement than termination on strings. Most

  14. Data base for a CANDU-PHW operating on the thorium cycle

    International Nuclear Information System (INIS)

    1979-07-01

    This report, prepared for INFCE, gives data for an extrapolated 1000 MW(e) CANDU-PHW design operating on various thorium cycles. In the reference cycle, the requirements for externally supplied fissile material are met using U-235, with the feed adjusted to provide a fuel burnup of approximately 30 000 MW.d/t(U). Two versions of the reference cycle are treated. In one, the U-235 is supplied in a highly enriched form (93 percent U-235 in uranium); in the other, the U-235 is supplied at a lower enrichment, such that the uranium present in the feed fuel is 'denatured'. The effects of varying the fuel burnup and the recycle delay time are discussed. Data are also given for thorium cycles using plutonium instead of U-235 to meet requirements for externally-supplied fissile material. The special case of 'self-sufficient equilibrium thorium cycles', which require no external source of fissile material for equilibrium operation, is also treated. (author)

  15. From Cycling Between Coupled Reactions to the Cross-Bridge Cycle: Mechanical Power Output as an Integral Part of Energy Metabolism

    Directory of Open Access Journals (Sweden)

    Frank Diederichs

    2012-10-01

    Full Text Available ATP delivery and its usage are achieved by cycling of respective intermediates through interconnected coupled reactions. At steady state, cycling between coupled reactions always occurs at zero resistance of the whole cycle without dissipation of free energy. The cross-bridge cycle can also be described by a system of coupled reactions: one energising reaction, which energises myosin heads by coupled ATP splitting, and one de-energising reaction, which transduces free energy from myosin heads to coupled actin movement. The whole cycle of myosin heads via cross-bridge formation and dissociation proceeds at zero resistance. Dissipation of free energy from coupled reactions occurs whenever the input potential overcomes the counteracting output potential. In addition, dissipation is produced by uncoupling. This is brought about by a load dependent shortening of the cross-bridge stroke to zero, which allows isometric force generation without mechanical power output. The occurrence of maximal efficiency is caused by uncoupling. Under coupled conditions, Hill’s equation (velocity as a function of load is fulfilled. In addition, force and shortening velocity both depend on [Ca2+]. Muscular fatigue is triggered when ATP consumption overcomes ATP delivery. As a result, the substrate of the cycle, [MgATP2−], is reduced. This leads to a switch off of cycling and ATP consumption, so that a recovery of [ATP] is possible. In this way a potentially harmful, persistent low energy state of the cell can be avoided.

  16. The Nuclear Fuel Cycle

    International Nuclear Information System (INIS)

    2011-08-01

    This brochure describes the nuclear fuel cycle, which is an industrial process involving various activities to produce electricity from uranium in nuclear power reactors. The cycle starts with the mining of uranium and ends with the disposal of nuclear waste. The raw material for today's nuclear fuel is uranium. It must be processed through a series of steps to produce an efficient fuel for generating electricity. Used fuel also needs to be taken care of for reuse and disposal. The nuclear fuel cycle includes the 'front end', i.e. preparation of the fuel, the 'service period' in which fuel is used during reactor operation to generate electricity, and the 'back end', i.e. the safe management of spent nuclear fuel including reprocessing and reuse and disposal. If spent fuel is not reprocessed, the fuel cycle is referred to as an 'open' or 'once-through' fuel cycle; if spent fuel is reprocessed, and partly reused, it is referred to as a 'closed' nuclear fuel cycle.

  17. Impacts of nuclear fuel cycle costs on nuclear power generating costs

    International Nuclear Information System (INIS)

    Bertel, E.; Naudet, G.

    1989-01-01

    Fuel cycle costs are one of the main parameters to evaluate the competitiveness of various nuclear strategies. The historical analysis based on the French case shows the good performances yet achieved in mastering elementary costs in order to limit global fuel cycle cost escalation. Two contrasted theoretical scenarios of costs evolution in the middle and long term have been determined, based upon market analysis and technological improvements expected. They are used to calculate the global fuel cycle costs for various fuel management options and for three strategies of nuclear deployment. The results illustrate the stability of the expected fuel cycle costs over the long term, to be compared to the high incertainty prevailing for fossil fueled plants. The economic advantages of advanced technologies such as MOX fueled PWRs are underlined

  18. Can cycling safety be improved by opening all unidirectional cycle paths for cycle traffic in both directions? A theoretical examination of available literature and data.

    Science.gov (United States)

    Methorst, Rob; Schepers, Paul; Kamminga, Jaap; Zeegers, Theo; Fishman, Elliot

    2017-08-01

    Many studies have found bicycle-motor vehicle crashes to be more likely on bidirectional cycle paths than on unidirectional cycle paths because drivers do not expect cyclists riding at the right side of the road. In this paper we discuss the hypothesis that opening all unidirectional cycle paths for cycle traffic in both directions prevent this lack of expectancy and accordingly improves cycling safety. A new national standard requires careful consideration because a reversal is difficult once cyclists are used to their new freedom of route choice. We therefore explored the hypothesis using available data, research, and theories. The results show that of the length of cycle paths along distributor roads in the Netherlands, 72% is bidirectional. If drivers would become used to cyclists riding at the left side of the road, this result raises the question of why bidirectional cycle paths in the Netherlands still have a poor safety record compared to unidirectional cycle paths. Moreover, our exploration suggested that bidirectional cycle paths have additional safety problems. It increases the complexity of unsignalized intersections because drivers have to scan more directions in a short period of time. Moreover, there are some indications that the likelihood of frontal crashes between cyclists increases. We reject the hypothesis that opening all unidirectional cycle paths for cycle traffic in both directions will improve cycle safety. We recommend more attention for mitigating measures given the widespread application of bidirectional cycle paths in the Netherlands. Copyright © 2016 Elsevier Ltd. All rights reserved.

  19. Life-cycle analysis of renewable energy systems

    DEFF Research Database (Denmark)

    Sørensen, Bent

    1994-01-01

    An imlementation of life-cycle analysis (LCA) for energy systems is presented and applied to two renewable energy systems (wind turbines and building-integrated photovoltaic modules) and compared with coal plants......An imlementation of life-cycle analysis (LCA) for energy systems is presented and applied to two renewable energy systems (wind turbines and building-integrated photovoltaic modules) and compared with coal plants...

  20. Evaporative cycles - in theory and in practise

    Energy Technology Data Exchange (ETDEWEB)

    Rosen, P.M.

    2000-08-01

    operation in three reversible steps: 1. Simple open gas turbine cycle; 2. Recuperative gas turbine cycle; 3. Evaporative gas turbine cycle. The braked efficiency of the gas turbine engine increased from 22% for the simple cycle to 35% for the evaporative cycle. The NO{sub x} was reduced by about 90% for the evaporative cycle compared to the simple cycle. Single digit NO{sub x} emission levels were measured in the normal operation interval using a simple diffusion flame combustion chamber operating on natural gas. However, the pilot plant has been optimised neither for best performance nor for best emissions values; instead the main goal was just to show an operable evaporative gas turbine unit and to verify performance calculations. During the work, a spin-off idea, the HAM-concept (Humid Air Motor), was introduced. In the HAM-concept, a turbo-charged reciprocate combustion engine is equipped with a humidification tower situated between the turbo-charger and the engine. This action reduces NO{sub x} emissions and raises the efficiency of the engine, and at the same time, operates as an online cleaning device of the engine. Today this concept has been demonstrated in a full scale marine retrofit application with good results. In fact, the HAM-concept is presently on the brink of being commercialised. In the struggle to find a good cogeneration solution of the evaporative cycles and at the same time to close the water loop completely, one new idea further arose. This new concept is presented for the first time in this thesis. The concept is called the 'The TRIGENERATION Technology' due to its possibility of offering three benefits from one cycle. These cycles will have the possibility of reaching higher than 100% total efficiency even if the performance calculations are based on the higher heating value of the fuel. Due to the stable and thermodynamically favourable way the pressurised humidification tower operates in evaporative cycles, its compactness, combined

  1. Fuel management options to extend the IRIS reactor cycle

    International Nuclear Information System (INIS)

    Petrovic, B.; Franceschini, F.

    2004-01-01

    To optimize plant operation, reduce scheduled maintenance outage, and increase capacity factor, IRIS is designed to enable extended cycles of up to four years. However, due to the enrichment licensing limitation (less than 5% enriched uranium oxide) there is a tradeoff between the achievable cycle length and fuel utilization, i.e., the average fuel discharge burnup. The longest individual cycle may be achieved with the single-batch straight burn, but at the expense of a lower burnup. Considering the IRIS basic performance requirements, a cycle length in the range of three to four years is deemed desirable. This paper examines different fuel management options, i.e., the influence of the required cycle length on the corresponding reloading strategy, including a two-batch and a three-batch reloading. A reference two-batch core design has been developed for the first cycle, as well as for the transition cycles leading to equilibrium. Main core performance parameters are evaluated. This core design provides the framework for the safety analyses needed to prepare the IRIS safety evaluations. Alternate designs are also considered.(author)

  2. Contrasting the solar rotation rate of cycles 23 and 24

    International Nuclear Information System (INIS)

    Antia, H M; Basu, Sarbani

    2013-01-01

    The minimum between solar cycles 23 and 24 was quite unusual compared with other minima for which detailed data are available and this pointed to the possibility that cycle 24 will be unusual. Cycle 24 is almost at its maximum now and we take this opportunity to compare and contrast the solar rotation rate and zonal flows between the two cycles. We find that the rotation rate during cycle 24 is slightly lower than that during cycle 23. Additionally we find that the poleward branch of the zonal flow that is believed to be the harbinger of the next solar cycle is very week in cycle 24.

  3. Thermally regenerative hydrogen/oxygen fuel cell power cycles

    Science.gov (United States)

    Morehouse, J. H.

    1986-01-01

    Two innovative thermodynamic power cycles are analytically examined for future engineering feasibility. The power cycles use a hydrogen-oxygen fuel cell for electrical energy production and use the thermal dissociation of water for regeneration of the hydrogen and oxygen. The TDS (thermal dissociation system) uses a thermal energy input at over 2000 K to thermally dissociate the water. The other cycle, the HTE (high temperature electrolyzer) system, dissociates the water using an electrolyzer operating at high temperature (1300 K) which receives its electrical energy from the fuel cell. The primary advantages of these cycles is that they are basically a no moving parts system, thus having the potential for long life and high reliability, and they have the potential for high thermal efficiency. Both cycles are shown to be classical heat engines with ideal efficiency close to Carnot cycle efficiency. The feasibility of constructing actual cycles is investigated by examining process irreversibilities and device efficiencies for the two types of cycles. The results show that while the processes and devices of the 2000 K TDS exceed current technology limits, the high temperature electrolyzer system appears to be a state-of-the-art technology development. The requirements for very high electrolyzer and fuel cell efficiencies are seen as determining the feasbility of the HTE system, and these high efficiency devices are currently being developed. It is concluded that a proof-of-concept HTE system experiment can and should be conducted.

  4. Issues in the selection of the LMFBR steam cycle

    International Nuclear Information System (INIS)

    Buschman, H.W.; McConnell, R.J.

    1983-01-01

    Unlike the light-water reactor, the liquid-metal fast breeder reactor (LMFBR) allows the designer considerable latitude in the selection of the steam cycle. This latitude in selection has been exercised by both foreign and domestic designers, and thus, despite the fact that over 25 LMFBR's have been built or are under construction, a consensus steam cycle has not yet evolved. This paper discusses the LMFBR steam cycles of interest to the LMFBR designer, reviews which of these cycles have been employed to date, discusses steam-cycle selection factors, discusses why a consensus has not evolved, and finally, concludes that the LMFBR steam-cycle selection is primarily one of technical philosophy with several options available

  5. Supercharged two-cycle engines employing novel single element reciprocating shuttle inlet valve mechanisms and with a variable compression ratio

    Science.gov (United States)

    Wiesen, Bernard (Inventor)

    2008-01-01

    This invention relates to novel reciprocating shuttle inlet valves, effective with every type of two-cycle engine, from small high-speed single cylinder model engines, to large low-speed multiple cylinder engines, employing spark or compression ignition. Also permitting the elimination of out-of-phase piston arrangements to control scavenging and supercharging of opposed-piston engines. The reciprocating shuttle inlet valve (32) and its operating mechanism (34) is constructed as a single and simple uncomplicated member, in combination with the lost-motion abutments, (46) and (48), formed in a piston skirt, obviating the need for any complex mechanisms or auxiliary drives, unaffected by heat, friction, wear or inertial forces. The reciprocating shuttle inlet valve retains the simplicity and advantages of two-cycle engines, while permitting an increase in volumetric efficiency and performance, thereby increasing the range of usefulness of two-cycle engines into many areas that are now dominated by the four-cycle engine.

  6. CANDU fuel cycle options in Korea

    International Nuclear Information System (INIS)

    Boczar, P. G.; Fehrenbach, P. J.; Meneley, D. A.

    1996-01-01

    There are many reasons for countries embarking on a CANDU R program to start with the natural uranium fuel cycle. Simplicity of fuel design, ease of fabrication, and ready availability of natural uranium all help to localize the technology and to reduce reliance on foreign technology. Nonetheless, at some point, the incentives for using natural uranium fuel may be outweighed by the advantages of alternate fuel cycles. The excellent neutron economy, on-line refuelling, and simple fuel-bundle design provide an unsurpassed degree of fuel-cycle flexibility in CANDU reactors. The easiest first step in CANDU fuel-cycle evolution may be the use of slightly enriched uranium (SEU), including recovered uranium from reprocessed LWR spent fuel. Relatively low enrichment (up to 1.2%) will result in a two- to three-fold reduction in the quantity of spent fuel per unit energy production, reductions in fuel-cycle costs, and greater flexibility in the design of new reactors. The CANFLEX (CANDU FLEXible) fuel bundle would be the optimal fuel carrier. A country that has both CANDU and PWR reactors can exploit the natural synergism between these two reactor types to minimize overall waste production, and maximize energy derived from the fuel. This synergism can be exploited through several different fuel cycles. A high burnup CANDU MOX fuel design could be used to utilize plutonium from conventional reprocessing or more advanced reprocessing options (such as co-processing). DUPIC (Direct Use of Spent PWR Fuel In CANDU) represents a recycle option that has a higher degree of proliferation resistance than dose conventional reprocessing, since it uses only dry processes for converting spent PWR fuel into CANDU fuel, without separating the plutonium. Good progress is being made in the current KAERI, AECL, and U. S. Department of State program in demonstrating the technical feasibility of DUPIC. In the longer term, CANDU reactors offer even more dramatic synergistic fuel cycles with PWR or

  7. Nuclear Fuel Cycle Information System. A directory of nuclear fuel cycle facilities. 2009 ed

    International Nuclear Information System (INIS)

    2009-04-01

    The Nuclear Fuel Cycle Information System (NFCIS) is an international directory of civilian nuclear fuel cycle facilities, published online as part of the Integrated Nuclear Fuel Cycle Information System (iNFCIS: http://www-nfcis.iaea.org/). This is the fourth hardcopy publication in almost 30 years and it represents a snapshot of the NFCIS database as of the end of 2008. Together with the attached CD-ROM, it provides information on 650 civilian nuclear fuel cycle facilities in 53 countries, thus helping to improve the transparency of global nuclear fuel cycle activities

  8. Business Cycles in Developing Countries

    DEFF Research Database (Denmark)

    Rand, John; Tarp, Finn

    2002-01-01

    This paper demonstrates that developing countries differ considerably from their developed counterparts when focus is on the nature and characteristics of short run macroeconomic fluctuations. Cycles are generally shorter, and the stylized facts of business cycles across countries are more diverse...... than those of the rather uniform industrialized countries. Supply-side models are generally superior in explaining changes in output, but a “one-size fits all” approach in formulating policy is inappropriate. Our results also illustrate the critical importance of understanding business regularities...

  9. Energy systems. Tome 3: advanced cycles, low environmental impact innovative systems

    International Nuclear Information System (INIS)

    Gicquel, R.

    2009-01-01

    This third tome about energy systems completes the two previous ones by showing up advanced thermodynamical cycles, in particular having a low environmental impact, and by dealing with two other questions linked with the study of systems with a changing regime operation: - the time management of energy, with the use of thermal and pneumatic storage systems and time simulation (schedule for instance) of systems (solar energy type in particular); - the technological dimensioning and non-nominal regime operation studies. Because this last topic is particularly complex, new functionalities have been implemented mainly by using the external classes mechanism, which allows the user to freely personalize his models. This tome is illustrated with about 50 examples of cycles modelled with Thermoptim software. Content: foreword; 1 - generic external classes; 2 - advanced gas turbine cycles; 3 - evaporation-concentration, mechanical steam compression, desalination, hot gas drying; 4 - cryogenic cycles; 5 - electrochemical converters; 6 - global warming, CO 2 capture and sequestration; 7 - future nuclear reactors (coupled to Hirn and Brayton cycles); 8 - thermodynamic solar cycles; 10 - pneumatic and thermal storage; 11 - calculation of thermodynamic solar facilities; 12 - problem of technological dimensioning and non-nominal regime; 13 - exchangers modeling and parameterizing for the dimensioning and the non-nominal regime; 14 - modeling and parameterizing of volumetric compressors; 15 - modeling and parameterizing of turbo-compressors and turbines; 16 - identification methodology of component parameters; 17 - case studies. (J.S.)

  10. Bifuel coal-gas combined cycles

    International Nuclear Information System (INIS)

    Chmielniak, Tadeusz; Kotowicz, Janusz; Lyczko, Jacek

    1997-01-01

    This paper describes basic ways of realization of bi fuel cool-gas combined cycles. The criterion of classification of the systems specification is a joint of the gas pail with the steam part: a) The gas turbine flue gases are introduced into the steam boiler combustion chamber (the serial, hot wind box). b) Bypass of the beat exchangers at the steam turbine unit and/or the steam boiler, by use the waste heat exchangers, or waste boiler at the gas turbine unit (the parallel-coupled). c) The mixed, it's a combination of the two upper. The analysis of the parallel system has been specially presented. In derived formulas for the total efficiency of the bi fuel parallel combined cycle balance equations have been used. This formulas can be used for planning new combined cycle power plants and for modernization existing steam power plants. It was made a discussion about influence of the ratio the gas and the steam turbine electric power on the cycle efficiency in care of the full and the part load of the bi fuel combined cycle power plant. The various systems of the joint of the gas part with the steam part have been examined. The selected results of the calculations have been attached. The models and the numerical simulations have been based on data from the existing steam power plants and real gas turbine units. (Author)

  11. Nonproliferation norms in civilian nuclear fuel cycle

    International Nuclear Information System (INIS)

    Kawata, Tomio

    2005-01-01

    For sustainable use of nuclear energy in large scale, it seems inevitable to choose a closed cycle option. One of the important questions is, then, whether we can really achieve the compatibility between civilian nuclear fuel cycle and nonproliferation norms. In this aspect, Japan is very unique because she is now only one country with full-scope nuclear fuel cycle program as a non-nuclear weapon state in NPT regime. In June 2004 in the midst of heightened proliferation concerns in NPT regime, the IAEA Board of Governors concluded that, for Japanese nuclear energy program, non-diversion of declared nuclear material and the absence of undeclared nuclear material and activities were verified through the inspections and examinations under Comprehensive Safeguards and the Additional Protocol. Based on this conclusion, the IAEA announced the implementation of Integrated Safeguards in Japan in September 2004. This paper reviews how Japan has succeeded in becoming the first country with full-scope nuclear fuel cycle program to qualify for integrated Safeguards, and identifies five key elements that have made this achievement happen: (1) Obvious need of nuclear fuel cycle program, (2) Country's clear intention for renunciation of nuclear armament, (3) Transparency of national nuclear energy program, (4) Record of excellent compliance with nonproliferation obligations for many decades, and (5) Numerous proactive efforts. These five key elements will constitute a kind of an acceptance model for civilian nuclear fuel cycle in NNWS, and may become the basis for building 'Nonproliferation Culture'. (author)

  12. Fatigue diminishes motoneuronal excitability during cycling exercise.

    Science.gov (United States)

    Weavil, Joshua C; Sidhu, Simranjit K; Mangum, Tyler S; Richardson, Russell S; Amann, Markus

    2016-10-01

    Exercise-induced fatigue influences the excitability of the motor pathway during single-joint isometric contractions. This study sought to investigate the influence of fatigue on corticospinal excitability during cycling exercise. Eight men performed fatiguing constant-load (80% W peak ; 241 ± 13 W) cycling to exhaustion during which the percent increase in quadriceps electromyography (ΔEMG; vastus lateralis and rectus femoris) was quantified. During a separate trial, subjects performed two brief (∼45 s) nonfatiguing cycling bouts (244 ± 15 and 331 ± 23W) individually chosen to match the ΔEMG across bouts to that observed during fatiguing cycling. Corticospinal excitability during exercise was quantified by transcranial magnetic, electric transmastoid, and femoral nerve stimulation to elicit motor-evoked potentials (MEP), cervicomedullary evoked potentials (CMEP), and M waves in the quadriceps. Peripheral and central fatigue were expressed as pre- to postexercise reductions in quadriceps twitch force (ΔQ tw ) and voluntary quadriceps activation (ΔVA). Whereas nonfatiguing cycling caused no measureable fatigue, fatiguing cycling resulted in significant peripheral (ΔQ tw : 42 ± 6%) and central (ΔVA: 4 ± 1%) fatigue. During nonfatiguing cycling, the area of MEPs and CMEPs, normalized to M waves, similarly increased in the quadriceps (∼40%; P fatiguing cycling. As a consequence, the ratio of MEP to CMEP was unchanged during both trials (P > 0.5). Therefore, although increases in muscle activation promote corticospinal excitability via motoneuronal facilitation during nonfatiguing cycling, this effect is abolished during fatigue. We conclude that the unaltered excitability of the corticospinal pathway from start of intense cycling exercise to exhaustion is, in part, determined by inhibitory influences on spinal motoneurons obscuring the facilitating effects of muscle activation.

  13. Entrepreneurship and the business cycle

    NARCIS (Netherlands)

    Koellinger, Philipp D.; Thurik, A. Roy

    2012-01-01

    We find new empirical regularities in the business cycle in a cross-country panel of 22 OECD countries for the period 1972 to 2007; entrepreneurship Granger-causes the cycles of the world economy. Furthermore, the entrepreneurial cycle is positively affected by the national unemployment cycle. We

  14. Continuation of connecting orbits in 3d-ODEs. (ii) cycle-to-cycle connections.

    NARCIS (Netherlands)

    Doedel, E.J.; Kooi, B.W.; van Voorn, G.A.K.; Kuznetzov, Y.A.

    2009-01-01

    In Part I of this paper we have discussed new methods for the numerical continuation of point-to-cycle connecting orbits in three-dimensional autonomous ODE's using projection boundary conditions. In this second part we extend the method to the numerical continuation of cycle-to-cycle connecting

  15. Thermodynamic analysis of SCW NPP cycles with thermo-chemical co-generation of hydrogen

    International Nuclear Information System (INIS)

    Naidin, N.; Mokry, S.; Monichan, R.; Chophla, K.; Pioro, I.; Naterer, G.; Gabriel, K.

    2009-01-01

    Research activities are currently conducted worldwide to develop Generation IV nuclear reactor concepts with the objective of improving thermal efficiency and increasing economic competitiveness of Generation IV Nuclear Power Plants (NPPs) compared to modern thermal power plants. The Super-Critical Water-cooled Reactor (SCWR) concept is one of the six Generation IV options chosen for further investigation and development in several countries including Canada and Russia. Water-cooled reactors operating at subcritical pressures (10 - 16 MPa) have provided a significant amount of electricity production for the past 50 years. However, the thermal efficiency of the current NPPs is not very high (30 - 35%). As such, more competitive designs, with higher thermal efficiencies, which will be close to that of modern thermal power plants (45 - 50%), need to be developed and implemented. Super-Critical Water (SCW) NPPs will have much higher operating parameters compared to current NPPs (i.e., steam pressures of about 25 MPa and steam outlet temperatures up to 625 o C). Furthermore, SCWRs operating at higher temperatures can facilitate an economical co-generation of hydrogen through thermochemical cycles (particularly, the copper-chlorine cycle) or direct high-temperature electrolysis. The two SCW NPP cycles proposed by this paper are based on direct, regenerative, no-reheat and single-reheat configurations. As such, the main parameters and performance in terms of thermal efficiency of the SCW NPP concepts mentioned above are being analyzed. The cycles are generally comprised of: an SCWR, a SC turbine, one deaerator, ten feedwater heaters, and pumps. The SC turbine of the no-reheat cycle consists of one High-Pressure (HP) cylinder and two Low-Pressure (LP) cylinders. Alternatively, the SC turbine for the single-reheat cycle is comprised of one High-Pressure (HP) cylinder, one Intermediate-Pressure (IP) cylinder and two Low-Pressure (LP) cylinders. Since the single-reheat option

  16. Nuclear Fuel Cycle Objectives

    International Nuclear Information System (INIS)

    2013-01-01

    One of the IAEA's statutory objectives is to 'seek to accelerate and enlarge the contribution of atomic energy to peace, health and prosperity throughout the world'. One way this objective is achieved is through the publication of a range of technical series. Two of these are the IAEA Nuclear Energy Series and the IAEA Safety Standards Series. According to Article III.A.6 of the IAEA Statute, the safety standards establish 'standards of safety for protection of health and minimization of danger to life and property'. The safety standards include the Safety Fundamentals, Safety Requirements and Safety Guides. These standards are written primarily in a regulatory style, and are binding on the IAEA for its own programmes. The principal users are the regulatory bodies in member States and other national authorities. The IAEA Nuclear Energy Series comprises reports designed to encourage and assist R and D on, and application of, nuclear energy for peaceful uses. This includes practical examples to be used by owners and operators of utilities in member States, implementing organizations, academia and government officials, among others. This information is presented in guides, reports on technology status and advances, and best practices for peaceful uses of nuclear energy based on inputs from international experts. The IAEA Nuclear Energy Series complements the IAEA Safety Standards Series. The Nuclear Energy Basic Principles is the highest level publication in the IAEA Nuclear Energy Series, and describes the rationale and vision for the peaceful uses of nuclear energy. It presents eight Basic Principles on which nuclear energy systems should be based to fulfil nuclear energy's potential to help meet growing global energy needs. The Nuclear Energy Series Objectives are the second level publications. They describe what needs to be considered and the specific goals to be achieved at different stages of implementation, all of which are consistent with the Basic Principles

  17. Two scale damage model and related numerical issues for thermo-mechanical high cycle fatigue

    International Nuclear Information System (INIS)

    Desmorat, R.; Kane, A.; Seyedi, M.; Sermage, J.P.

    2007-01-01

    On the idea that fatigue damage is localized at the microscopic scale, a scale smaller than the mesoscopic one of the Representative Volume Element (RVE), a three-dimensional two scale damage model has been proposed for High Cycle Fatigue applications. It is extended here to aniso-thermal cases and then to thermo-mechanical fatigue. The modeling consists in the micro-mechanics analysis of a weak micro-inclusion subjected to plasticity and damage embedded in an elastic meso-element (the RVE of continuum mechanics). The consideration of plasticity coupled with damage equations at micro-scale, altogether with Eshelby-Kroner localization law, allows to compute the value of microscopic damage up to failure for any kind of loading, 1D or 3D, cyclic or random, isothermal or aniso-thermal, mechanical, thermal or thermo-mechanical. A robust numerical scheme is proposed in order to make the computations fast. A post-processor for damage and fatigue (DAMAGE-2005) has been developed. It applies to complex thermo-mechanical loadings. Examples of the representation by the two scale damage model of physical phenomena related to High Cycle Fatigue are given such as the mean stress effect, the non-linear accumulation of damage. Examples of thermal and thermo-mechanical fatigue as well as complex applications on real size testing structure subjected to thermo-mechanical fatigue are detailed. (authors)

  18. A CASKCOM: A cask life cycle cost model

    International Nuclear Information System (INIS)

    Anon.

    1989-01-01

    CASKCOM (cask cost model) is a computerized model which calculates the life cycle costs (LCC) associated with specific transportation cask designs and discounts those costs, if the user so chooses, to a net present value. The model has been used to help analyze and compare the life cycle economics of burnup credit and nonburnup credit cask designs being considered as conditions for a new generation of spent fuel transportation casks. CASKCOM is parametric in the sense that its input data can be easily changed in order to analyze and compare the life cycle cost implications arising from alternative assumptions. The input data themselves are organized into two main groupings. The first grouping comprises a set of data which is independent of cask design. This first grouping does not change from the analysis of one cask design to another. The second grouping of data is specific to each individual cask design. This second grouping thus changes each time a new cask design is analyzed

  19. LIFE CYCLE OF INFORMATION SYSTEMS

    Directory of Open Access Journals (Sweden)

    Y. S. Sennik

    2015-01-01

    Full Text Available This work is a generalization of the theoretical propositions related to the life cycle of information systems. There was given the definition of the life cycle, specify which items you should include every step of the cycle. Describes the methodology division of the life cycle on the main stage, including methodology Rational Unified Process. The description of the fundamental standards in this area. Special attention was paid to the work of the basic life cycle models. It was carried out their comparative characteristics. On the basis of the theoretical propositions, it was concluded that the preferred model of the life cycle for the corporate network is a spiral model and the use of international standards in the life cycle saves a lot of effort, time and material resources.

  20. Chromatin association of UHRF1 during the cell cycle

    KAUST Repository

    Al-Gashgari, Bothayna

    2017-05-01

    Ubiquitin-like with PHD and RING Finger domains 1 (UHRF1) is a nuclear protein that associates with chromatin. Regardless of the various functions of UHRF1 in the cell, one of its more important functions is its role in the maintenance of DNA methylation patterns by the recruitment of DNMT1. Studies on UHRF1 based on this function have revealed the importance of UHRF1 during the cell cycle. Moreover, based on different studies various factors were described to be involved in the regulation of UHRF1 with different functionalities that can control its binding affinity to different targets on chromatin. These factors are regulated differently in a cell cycle specific manner. In light of this, we propose that UHRF1 has different binding behaviors during the cell cycle in regard to its association with chromatin. In this project, we first analyzed the binding behavior of endogenous UHRF1 from different unsynchronized cell systems in pull-down assays with peptides and oligonucleotides. Moreover, to analyze UHRF1 binding behavior during the cell cycle, we used two different approaches. First we sorted Jurkat and HT1080 cells based on their cell cycle stage using FACS analysis. Additionally, we synchronized HeLa cells to different stages of the cell cycle by chemical treatments, and used extracts from cellsorting and cell synchronization experiments for pull-down assays. We observed that UHRF1 in different cell systems has different preferences in regard to its binding to H3 unmodified and H3K9me3. Moreover, we detected that UHRF1, in general, displays different patterns between different stages of cell cycle; however, we cannot draw a final model for UHRF1 binding pattern during cell cycle.

  1. Increasing thermal efficiency of Rankine cycles by using refrigeration cycles: A theoretical analysis

    International Nuclear Information System (INIS)

    Sarr, Joachim-André Raymond; Mathieu-Potvin, François

    2016-01-01

    Highlights: • A new stratagem is proposed to improve thermal efficiency of Rankine cycles. • Three new configurations are optimized by means of numerical simulations. • The Rankine-1SCR design is advantageous for 1338 different fluid combinations. • The Rankine-2SCR design is advantageous for 772 different fluid combinations. • The Rankine-3SCR design is advantageous for 768 different fluid combinations. - Abstract: In this paper, three different modifications of the basic Rankine thermodynamic cycle are proposed. The objective is to increase the thermal efficiency of power systems based on Rankine cycles. The three new systems are named “Rankine-1SCR”, “Rankine-2SCR”, and “Rankine-3SCR” cycles, and they consist of linking a refrigeration cycle to the basic Rankine cycle. The idea is to use the refrigeration cycle to create a low temperature heat sink for the Rankine cycle. These three new power plant configurations are modeled and optimized with numerical tools, and then they are compared with the basic Rankine cycle. The objective function is the thermal efficiency of the systems (i.e., net power output (kW) divided by heat rate (kW) entering the system), and the design variables are the operating temperatures within the systems. Among the 84 × 84 (i.e., 7056) possible combinations of working and cooling fluids investigated in this paper, it is shown that: (i) the Rankine-1SCR system is advantageous for 1338 different fluid combinations, (ii) the Rankine-2SCR system is advantageous for 772 different fluid combinations, and (iii) the Rankine-3SCR system is advantageous for 768 different fluid combinations.

  2. Skills, sunspots and cycles

    DEFF Research Database (Denmark)

    Busato, Francesco; Marchetti, Enrico

    This paper explores the ability of a class of one-sector,multi-input models to generate indeterminate equilibrium paths, andendogenous cycles, without relying on factors' hoarding. The modelpresents a novel theoretical economic mechanism that supportssunspot-driven expansions without requiring...

  3. International Nuclear Fuel Cycle Fact Book

    International Nuclear Information System (INIS)

    Leigh, I.W.; Mitchell, S.J.

    1990-01-01

    As the US Department of Energy (DOE) and DOE contractors have become increasingly involved with other nations in nuclear fuel cycle and waste management cooperative activities, a need has developed for a ready source of information concerning foreign fuel cycle programs, facilities, and personnel. This Fact Book was compiled to meet that need. The information contained in the International Nuclear Fuel Cycle Fact Book has been obtained from many unclassified sources: nuclear trade journals and newsletters; reports of foreign visits and visitors; CEC, IAEA, and OECD/NEA activities reports; proceedings of conferences and workshops, etc. The data listed do not reflect any one single source but frequently represent a consolidation/combination of information

  4. International Nuclear Fuel Cycle Fact Book

    Energy Technology Data Exchange (ETDEWEB)

    Leigh, I W; Mitchell, S J

    1990-01-01

    As the US Department of Energy (DOE) and DOE contractors have become increasingly involved with other nations in nuclear fuel cycle and waste management cooperative activities, a need has developed for a ready source of information concerning foreign fuel cycle programs, facilities, and personnel. This Fact Book was compiled to meet that need. The information contained in the International Nuclear Fuel Cycle Fact Book has been obtained from many unclassified sources: nuclear trade journals and newsletters; reports of foreign visits and visitors; CEC, IAEA, and OECD/NEA activities reports; proceedings of conferences and workshops, etc. The data listed do not reflect any one single source but frequently represent a consolidation/combination of information.

  5. Gas--steam turbine combined cycle power plants

    Energy Technology Data Exchange (ETDEWEB)

    Christian, J.E.

    1978-10-01

    The purpose of this technology evaluation is to provide performance and cost characteristics of the combined gas and steam turbine, cycle system applied to an Integrated Community Energy System (ICES). To date, most of the applications of combined cycles have been for electric power generation only. The basic gas--steam turbine combined cycle consists of: (1) a gas turbine-generator set, (2) a waste-heat recovery boiler in the gas turbine exhaust stream designed to produce steam, and (3) a steam turbine acting as a bottoming cycle. Because modification of the standard steam portion of the combined cycle would be necessary to recover waste heat at a useful temperature (> 212/sup 0/F), some sacrifice in the potential conversion efficiency is necessary at this temperature. The total energy efficiency ((electric power + recovered waste heat) divided by input fuel energy) varies from about 65 to 73% at full load to 34 to 49% at 20% rated electric power output. Two major factors that must be considered when installing a gas--steam turbine combines cycle are: the realiability of the gas turbine portion of the cycle, and the availability of liquid and gas fuels or the feasibility of hooking up with a coal gasification/liquefaction process.

  6. On cycles in the transcription network of Saccharomyces cerevisiae

    Directory of Open Access Journals (Sweden)

    Berman Piotr

    2008-01-01

    Full Text Available Abstract Background We investigate the cycles in the transcription network of Saccharomyces cerevisiae. Unlike a similar network of Escherichia coli, it contains many cycles. We characterize properties of these cycles and their place in the regulatory mechanism of the cell. Results Almost all cycles in the transcription network of Saccharomyces cerevisiae are contained in a single strongly connected component, which we call LSCC (L for "largest", except for a single cycle of two transcription factors. The fact that LSCC includes almost all cycles is well explained by the properties of a random graph with the same in- and out-degrees of the nodes. Among different physiological conditions, cell cycle has the most significant relationship with LSCC, as the set of 64 transcription interactions that are active in all phases of the cell cycle has overlap of 27 with the interactions of LSCC (of which there are 49. Conversely, if we remove the interactions that are active in all phases of the cell cycle (25% of interactions to transcription factors, the LSCC would have only three nodes and 5 edges, many fewer than expected. This subgraph of the transcription network consists mostly of interactions that are active only in the stress response subnetwork. We also characterize the role of LSCC in the topology of the network. We show that LSCC can be used to define a natural hierarchy in the network and that in every physiological subnetwork LSCC plays a pivotal role. Conclusion Apart from those well-defined conditions, the transcription network of Saccharomyces cerevisiae is devoid of cycles. It was observed that two conditions that were studied and that have no cycles of their own are exogenous: diauxic shift and DNA repair, while cell cycle and sporulation are endogenous. We claim that in a certain sense (slow recovery stress response is endogenous as well.

  7. Human Resource Development for Uranium Production Cycle

    International Nuclear Information System (INIS)

    Ganguly, C.

    2014-01-01

    Concluding Remarks & Suggestions: • HRD will be one of the major challenges in the expanding nuclear power program in countries like China and India. • China and India get uranium raw material from domestic mines and international market. In addition, China has overseas uranium property. India is also exploring the possibility of overseas Joint Venture and uranium properties. For uranium production cycle there is a need for trained geologist, mining engineers, chemical and mechanical engineers. • There is a need for introducing specialization course on “uranium production cycle” at post graduate levels in government and private universities. Overseas Utilities and private firms in India engaged in nuclear power and fuel cycle activities may like to sponsor MTech students with assurance of employment after the successful completion of the course. • The IAEA may consider to extend Technical Assistance to universities in HRD in nuclear power and fuel cycle in general and uranium production cycle in particular - IAEA workshops, with participation of international experts, on uranium geology, mining, milling and safety and best practices in uranium production cycle will be of great help. • The IAEA – UPSAT could play an important role in HRD in uranium production cycle

  8. Microbial nitrogen cycling in Arctic snowpacks

    International Nuclear Information System (INIS)

    Larose, Catherine; Vogel, Timothy M; Dommergue, Aurélien

    2013-01-01

    Arctic snowpacks are often considered as chemical reactors for a variety of chemicals deposited through wet and dry events, but are overlooked as potential sites for microbial metabolism of reactive nitrogen species. The fate of deposited species is critical since warming leads to the transfer of contaminants to snowmelt-fed ecosystems. Here, we examined the role of microorganisms and the potential pathways involved in nitrogen cycling in the snow. Next generation sequencing data were used to follow functional gene abundances and a 16S rRNA (ribosomal ribonucleic acid) gene microarray was used to follow shifts in microbial community structure during a two-month spring-time field study at a high Arctic site, Svalbard, Norway (79° N). We showed that despite the low temperatures and limited water supply, microbial communities inhabiting the snow cover demonstrated dynamic shifts in their functional potential to follow several different pathways of the nitrogen cycle. In addition, microbial specific phylogenetic probes tracked different nitrogen species over time. For example, probes for Roseomonas tracked nitrate concentrations closely and probes for Caulobacter tracked ammonium concentrations after a delay of one week. Nitrogen cycling was also shown to be a dominant process at the base of the snowpack. (letter)

  9. Effect of single- and two-cycle high hydrostatic pressure treatments on water properties, physicochemical and microbial qualities of minimally processed squids (todarodes pacificus).

    Science.gov (United States)

    Zhang, Yifeng; Jiao, Shunshan; Lian, Zixuan; Deng, Yun; Zhao, Yanyun

    2015-05-01

    This study investigated the effect of single- and two-cycle high hydrostatic pressure (HHP) treatments on water properties, physicochemical, and microbial qualities of squids (Todarodes pacificus) during 4 °C storage for up to 10 d. Single-cycle treatments were applied at 200, 400, or 600 MPa for 20 min (S-200, S-400, and S-600), and two-cycle treatments consisted of two 10 min cycles at 200, 400, or 600 MPa, respectively (T-200, T-400, and T-600). HHP-treated samples had higher (P pressure level caused no significant difference in water state of squids. The two-cycle HHP treatment was more effective in controlling total volatile basic nitrogen, pH, and total plate counts (TPC) of squids during storage, in which TPC of S-600 and T-600 was 2.9 and 1.8 log CFU/g at 10 d, respectively, compared with 7.5 log CFU/g in control. HHP treatments delayed browning discoloration of the squids during storage, and the higher pressure level and two-cycle HHP were more effective. Water properties highly corresponded with color and texture indices of squids. This study demonstrated that the two-cycle HHP treatment was more effective in controlling microbial growth and quality deterioration while having similar impact on the physicochemical and water properties of squids in comparison with the single-cycle treatment, thus more desirable for extending shelf-life of fresh squids. © 2015 Institute of Food Technologists®

  10. Impact of cycling cells and cell cycle regulation on Hydra regeneration.

    Science.gov (United States)

    Buzgariu, Wanda; Wenger, Yvan; Tcaciuc, Nina; Catunda-Lemos, Ana-Paula; Galliot, Brigitte

    2018-01-15

    Hydra tissues are made from three distinct populations of stem cells that continuously cycle and pause in G2 instead of G1. To characterize the role of cell proliferation after mid-gastric bisection, we have (i) used flow cytometry and classical markers to monitor cell cycle modulations, (ii) quantified the transcriptomic regulations of 202 genes associated with cell proliferation during head and foot regeneration, and (iii) compared the impact of anti-proliferative treatments on regeneration efficiency. We confirm two previously reported events: an early mitotic wave in head-regenerating tips, when few cell cycle genes are up-regulated, and an early-late wave of proliferation on the second day, preceded by the up-regulation of 17 cell cycle genes. These regulations appear more intense after mid-gastric bisection than after decapitation, suggesting a position-dependent regulation of cell proliferation during head regeneration. Hydroxyurea, which blocks S-phase progression, delays head regeneration when applied before but not after bisection. This result is consistent with the fact that the Hydra central region is enriched in G2-paused adult stem cells, poised to divide upon injury, thus forming a necessary constitutive pro-blastema. However a prolonged exposure to hydroxyurea does not block regeneration as cells can differentiate apical structures without traversing S-phase, and also escape in few days the hydroxyurea-induced S-phase blockade. Thus Hydra head regeneration, which is a fast event, is highly plastic, relying on large stocks of adult stem cells paused in G2 at amputation time, which immediately divide to proliferate and/or differentiate apical structures even when S-phase is blocked. Copyright © 2017 The Authors. Published by Elsevier Inc. All rights reserved.

  11. Introduction to nuclear supply chain management. In the context of fuel cycle strategy from LWR cycle system to FR cycle system

    International Nuclear Information System (INIS)

    Shiotani, Hiroki; Ono, Kiyoshi; Namba, Takashi; Yasumatsu, Naoto; Heta, Masanori

    2011-01-01

    Supply chain management (SCM) is an important technique to maintain supply and demand balance and to achieve total optimization from upstream to downstream in manufacturers' management. One of the major reasons why SCM receives much attention recently is the trend in production and sales systems from 'Push type' to 'Pull type'. 'Push type' can be restated as 'Make to Stock' (MTS). MTS is a type of supply chain in which the production is not connected to actual demand. On the contrary, 'Pull type' can be restated as 'Make to Order' (MTO) in which the production is connected to actual demand. In this paper, the terminologies and ideas of SCM was introduced into the scenario study to give a fresh perspective for considering LWR cycle to FR cycle transition strategies in Japan. Then, an analytical tool (SCM tool) which has been developed by the authors is used to survey Japanese nuclear energy system in transition with the SCM terminologies and viewpoints. When some of the Japanese nuclear fuel cycle strategies and tools are thought back with the framework of SCM, they tend to treat nuclear fuel cycle system as 'Push type' supply chain in their simulations. For example, a reprocessing plant separates SFs (spent fuels) without considering the actual Pu demand. However, because future reprocessing plants and fuel fabrication plants will act as Pu suppliers (front-end facility) to FR as well as back-end facilities of LWRs, the reasonable plant operation principle can be 'Pull type'. The analysis was conducted by the SCM tool to simulate the behaviors of both MTS and MTO type facilities during the LWR to FR transition period. If there are large uncertainties in the Pu demand or the load factor, etc. of future reprocessing plants, SCM framework is beneficial. Furthermore, the realization of MTO type operation by SCM can reduce the recovered Pu stock in spite of the increase of the SF interim storage. As the result of the investigation on the boundary location of 'Push type

  12. Solar High Temperature Water-Splitting Cycle with Quantum Boost

    Energy Technology Data Exchange (ETDEWEB)

    Taylor, Robin [SAIC; Davenport, Roger [SAIC; Talbot, Jan [UCSD; Herz, Richard [UCSD; Genders, David [Electrosynthesis Co.; Symons, Peter [Electrosynthesis Co.; Brown, Lloyd [TChemE

    2014-04-25

    A sulfur family chemical cycle having ammonia as the working fluid and reagent was developed as a cost-effective and efficient hydrogen production technology based on a solar thermochemical water-splitting cycle. The sulfur ammonia (SA) cycle is a renewable and sustainable process that is unique in that it is an all-fluid cycle (i.e., with no solids handling). It uses a moderate temperature solar plant with the solar receiver operating at 800°C. All electricity needed is generated internally from recovered heat. The plant would operate continuously with low cost storage and it is a good potential solar thermochemical hydrogen production cycle for reaching the DOE cost goals. Two approaches were considered for the hydrogen production step of the SA cycle: (1) photocatalytic, and (2) electrolytic oxidation of ammonium sulfite to ammonium sulfate in aqueous solutions. Also, two sub-cycles were evaluated for the oxygen evolution side of the SA cycle: (1) zinc sulfate/zinc oxide, and (2) potassium sulfate/potassium pyrosulfate. The laboratory testing and optimization of all the process steps for each version of the SA cycle were proven in the laboratory or have been fully demonstrated by others, but further optimization is still possible and needed. The solar configuration evolved to a 50 MW(thermal) central receiver system with a North heliostat field, a cavity receiver, and NaCl molten salt storage to allow continuous operation. The H2A economic model was used to optimize and trade-off SA cycle configurations. Parametric studies of chemical plant performance have indicated process efficiencies of ~20%. Although the current process efficiency is technically acceptable, an increased efficiency is needed if the DOE cost targets are to be reached. There are two interrelated areas in which there is the potential for significant efficiency improvements: electrolysis cell voltage and excessive water vaporization. Methods to significantly reduce water evaporation are

  13. The interplay of multiple sclerosis and menstrual cycle: Which one affects the other one?

    Science.gov (United States)

    Mirmosayyeb, Omid; Badihian, Shervin; Manouchehri, Navid; Basiri, Akram Kahid; Barzegar, Mahdi; Esmaeil, Nafiseh; Fayyazi, Emad; Shaygannejad, Vahid

    2018-02-02

    Menstruation is suggested to affect multiple sclerosis (MS) symptoms, while the effect of MS on menstruation is not studied before. Here, we aimed to compare the pattern of menstrual cycle and its symptoms between MS patients and healthy controls. This is a cross-sectional study conducted during 2015-2016 in MS clinic of Kashani hospital, Isfahan, Iran. We included female patients > 14 years with diagnosis of relapsing-remitting MS, and healthy subjects as the control group. We collected data regarding menarche age, menstrual characteristics, history of premenstrual syndrome, the amount of menstrual bleeding, and the possible perimenstrual symptoms from all subjects. Also, MS patients were asked to report changes in menstrual characteristics after MS occurrence. The final study population contained 181 MS patients and 202 healthy subjects. The mean age in MS and control group were 36.04 ± 9.86 and 35.16 ± 11.30, respectively (P-value = 0.426). Menarche age in MS patients and control group were not statistically different (13.59 ± 1.87 and 13.29 ± 1.53, respectively; P-value = 0.087). Changing menstrual characteristics was reported in 70 MS patients (38.7%). Irregular menstrual cycle increased from 21% to 40.3% after occurrence of MS (P-value < 0.001) and was reported 24.7% in the control group. MS patients versus controls reported more symptoms before, during, and after their menstrual period (P-values < 0.001). We found no difference regarding menstrual characteristics in MS patients before onset of the disease and healthy controls. Irregular menstrual cycle was observed more after the disease occurrence while other menstrual characteristics did not change. Moreover, MS patients reported many more perimenstrual symptoms. Copyright © 2018. Published by Elsevier B.V.

  14. Data base for a CANDU-PHW operating on the thorium cycle

    International Nuclear Information System (INIS)

    1979-07-01

    This report, prepared for INFCE, gives data for an extrapolated 1000 MW(e) CANDU-PHW design operating on various thorium cycles. In all these cycles thorium is the main fertile component of the fuel and all assume recycling of the uranium component. In the reference cycle, the requirements for externally supplied fissile material are met using U-235, with the feed adjusted to provide a fuel burnup of approximately 30,000 MW.d/t(U). Two versions of the reference cycle are treated. In one, the U-235 is supplied in a highly enriched form (93% U-235 in uranium); in the other, the U-235 is supplied at a lower enrichment, such that the uranium present in the feed fuel is ''denatured''. The effects of varying the fuel burnup and the recycle delay time are discussed for the reference cases. Data are also given for thorium cycles using plutonium instead of U-235 to meet requirements for externally supplied fissile material. The special case of ''self sufficient equilibrium thorium cycles'', which require no external source of fissile material for equilibrium operation, is also treated

  15. Numerical simulation and performance investigation of an advanced adsorption desalination cycle

    KAUST Repository

    Thu, Kyaw

    2013-01-01

    Low temperature waste heat-driven adsorption desalination (AD) cycles offer high potential as one of the most economically viable and environmental-friendly desalination methods. This article presents the development of an advanced adsorption desalination cycle that employs internal heat recovery between the evaporator and the condenser, utilizing an encapsulated evaporator-condenser unit for effective heat transfer. A simulation model has been developed based on the actual sorption characteristics of the adsorbent-adsorbate pair, energy and mass balances applied to the components of the AD cycle. With an integrated design, the temperature in the evaporator and the vapor pressurization of the adsorber are raised due to the direct heat recovery from the condenser, resulting in the higher water production rates, typically improved by as much as three folds of the conventional AD cycle. In addition, the integrated design eliminates two pumps, namely, the condenser cooling water and the chilled water pumps, lowering the overall electricity consumption. The performance of the cycle is analyzed at assorted heat source and cooling water temperatures, and different cycle times as well as the transient heat transfer coefficients of the evaporation and condensation. © 2012 Elsevier B.V.

  16. Menstrual cycle pattern and fertility

    DEFF Research Database (Denmark)

    Kolstad, Henrik A.; Bonde, Jens Peter; Hjøllund, Niels Henrik

    1999-01-01

    To characterize how the menstrual cycle pattern relates to fertility regardless of potential biases caused by inappropriate coital timing during the menstrual cycle or early embryonal loss.......To characterize how the menstrual cycle pattern relates to fertility regardless of potential biases caused by inappropriate coital timing during the menstrual cycle or early embryonal loss....

  17. Property Uncertainty Analysis and Methods for Optimal Working Fluids of Thermodynamic Cycles

    DEFF Research Database (Denmark)

    Frutiger, Jerome

    in the context of an industrial organic Rankine cycle, used for the recovery of waste heat from an engine of a marine container ship. The study illustrates that the model structure is vital for the uncertainties of equations of state and suggests that uncertainty becomes a criterion (along with e.g. goodness......-of-fit or ease of use) for the selection of an equation of state for a specific application. Furthermore, two studies on the identification of suitable working fluids for thermodynamic cycles are presented. The first one selects and assesses working fluid candidates for an organic Rankine cycle system to recover......There is an increasing interest in recovering industrial waste heat at low tempera-tures (70-250◦C). Thermodynamic cycles, such as heat pumps or organic Rankine cycles, can recover this heat and transfer it to other process streams or convert it into electricity. The working fluid, circulating...

  18. The urea cycle disorders.

    Science.gov (United States)

    Helman, Guy; Pacheco-Colón, Ileana; Gropman, Andrea L

    2014-07-01

    The urea cycle is the primary nitrogen-disposal pathway in humans. It requires the coordinated function of six enzymes and two mitochondrial transporters to catalyze the conversion of a molecule of ammonia, the α-nitrogen of aspartate, and bicarbonate into urea. Whereas ammonia is toxic, urea is relatively inert, soluble in water, and readily excreted by the kidney in the urine. Accumulation of ammonia and other toxic intermediates of the cycle lead to predominantly neurologic sequelae. The disorders may present at any age from the neonatal period to adulthood, with the more severely affected patients presenting earlier in life. Patients are at risk for metabolic decompensation throughout life, often triggered by illness, fasting, surgery and postoperative states, peripartum, stress, and increased exogenous protein load. Here the authors address neurologic presentations of ornithine transcarbamylase deficiency in detail, the most common of the urea cycle disorders, neuropathology, neurophysiology, and our studies in neuroimaging. Special attention to late-onset presentations is given. Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

  19. Resistance of human spermatozoa to cryoinjury in repeated cycles of thaw-refreezing

    Directory of Open Access Journals (Sweden)

    Sidney Verza Jr.

    2009-10-01

    Full Text Available Objective: To study the resistance of human spermatozoa to cryoinjury in repeated cycles of thaw-refreezing by using the fast liquid nitrogen vapor method. Material and Methods: Semen specimens were obtained from sixteen normal and oligozoospermic individuals who required disposal at the sperm bank. Five of them had testicular cancer. Specimens were thawed and an aliquot was removed for analysis. The remaining specimens were refrozen without removing the cryomedia. Repeated freeze-thaw cycles were performed until no motile sperm were observed. Sperm motility, number of motile spermatozoa and viability were determined after thawing. Resistance to cryoinjury was compared between groups and also after each refreezing cycle within groups. Results: Motile spermatozoa were recovered after five and two refreeze-thawing cycles in normozoospermic and oligozoospermic specimens, respectively. There were no significant differences in the recovery of motile spermatozoa between thaws within each group of normal and oligozoospermic specimens, but percentage motility and total number of motile spermatozoa were significantly lower in the oligozoospermic one. Specimens from men with cancer were exposed to six refreeze-thawing cycles. Although recovery of motile spermatozoa was significantly impaired after each thawing, there were no significant differences in the recovery of motile sperm between thaws in cancer and non-cancer groups. Conclusions: Human spermatozoa resist repeated cryopreservation using the fast liquid nitrogen vapor method. Normozoospermic specimens withstand refreezing for an average two cycles longer than oligozoospermic ones. Specimens from cancer patients seem to resist repeated cryoinjury similarly to non-cancer counterparts. Resistance to repeated cryoinjury was related to the initial semen quality.

  20. Life Cycle Collection Management

    Directory of Open Access Journals (Sweden)

    Helen Shenton

    2003-09-01

    Full Text Available Life cycle collection management is a way of taking a long-term approach to the responsible stewardship of the British Library's collections and is one of the Library's strategic strands. It defines the different stages in a collection item's existence over time. These stages range from selection and acquisitions processing, cataloguing and press marking, through to preventive conservation, storage and retrieval. Life cycle collection management seeks to identify the costs of each stage in order to show the economic interdependencies between the phases over time. It thereby aims to demonstrate the long-term consequences of what the library takes into its collections, by making explicit the financial and other implications of decisions made at the beginning of the life cycle for the next 100 plus years. This paper describes the work over the past year at the British Library on this complex and complicated subject. It presents the emerging findings and suggests how it can be used for practical reasons (by individual curators and selectors and for economic, governance and political purposes. The paper describes the next steps in the project, for example, on a predictive data model. The British Library is seeking to benchmark itself against comparable organisations in this area. It intends to work with others on specific comparison for example, of life cycle costing of electronic and paper journals, as a prelude to eliding digital and 'traditional' formats.

  1. Parallel Multi-cycle LES of an Optical Pent-roof DISI Engine Under Motored Operating Conditions

    Energy Technology Data Exchange (ETDEWEB)

    Van Dam, Noah; Sjöberg, Magnus; Zeng, Wei; Som, Sibendu

    2017-10-15

    The use of Large-eddy Simulations (LES) has increased due to their ability to resolve the turbulent fluctuations of engine flows and capture the resulting cycle-to-cycle variability. One drawback of LES, however, is the requirement to run multiple engine cycles to obtain the necessary cycle statistics for full validation. The standard method to obtain the cycles by running a single simulation through many engine cycles sequentially can take a long time to complete. Recently, a new strategy has been proposed by our research group to reduce the amount of time necessary to simulate the many engine cycles by running individual engine cycle simulations in parallel. With modern large computing systems this has the potential to reduce the amount of time necessary for a full set of simulated engine cycles to finish by up to an order of magnitude. In this paper, the Parallel Perturbation Methodology (PPM) is used to simulate up to 35 engine cycles of an optically accessible, pent-roof Directinjection Spark-ignition (DISI) engine at two different motored engine operating conditions, one throttled and one un-throttled. Comparisons are made against corresponding sequential-cycle simulations to verify the similarity of results using either methodology. Mean results from the PPM approach are very similar to sequential-cycle results with less than 0.5% difference in pressure and a magnitude structure index (MSI) of 0.95. Differences in cycle-to-cycle variability (CCV) predictions are larger, but close to the statistical uncertainty in the measurement for the number of cycles simulated. PPM LES results were also compared against experimental data. Mean quantities such as pressure or mean velocities were typically matched to within 5- 10%. Pressure CCVs were under-predicted, mostly due to the lack of any perturbations in the pressure boundary conditions between cycles. Velocity CCVs for the simulations had the same average magnitude as experiments, but the experimental data showed

  2. Influence of Fixed Temperature of Chilled Water Outlet Setting toward Performance of Chiller Absorbtion with Two Level Heating Cycle Method

    Directory of Open Access Journals (Sweden)

    I Gusti Agung Bagus Wirajati

    2012-11-01

    Full Text Available The study investigated the performance of re-heat two stage cycle. This paper presents the working principle and theexperimental results of the reheat two stage adsorption cycle. The performance of the cycle was evaluated under differentheat source temperature and mass recovery time. Coefficient of performance (COP and cooling capacity have beencalculated to analyze the influences of experimental conditions. The experimental results shown in both COP and coolingcapacity increased along with heat source temperature increased, and mass recovery time is very effective to improve theperformance without increasing heat source temperature.

  3. Spatio-temporal structure and cycle to cycle variations of an in-cylinder tumbling flow

    Science.gov (United States)

    Voisine, M.; Thomas, L.; Borée, J.; Rey, P.

    2011-05-01

    The aim of this paper is to make use of PIV and high-speed PIV in a research engine of moderate tumbling ratio in order to analyze both the spatial structure of the flow and its temporal evolution during series of consecutive cycles. Appropriate analyzing tools are introduced, and four different points are addressed: (1) the chain of events driving the generation of the three-dimensional mean tumbling motion is investigated; (2) a Lagrangian analysis of the roll-up of the tumbling jet in individual cycles demonstrates a strong cycle to cycle variation during the compression phase (the rms of the position of the jet front being approximately 10% of the piston stroke); (3) focussing on the "breakdown" phase, phase invariant proper orthogonal decomposition enables us to distinguish cycles according to their structure near top dead center (TDC). We show that when the coherent energy of the flow is conserved, there is no increase in the fluctuating kinetic energy; (4) finally, the phase-averaged Reynolds stresses is decomposed into a contribution of the in-cycle coherence and the turbulence carried by the flow states. Approximately 30% of the fluctuating kinetic energy is due to cycle to cycle fluctuations in this chamber near TDC.

  4. Nutrient cycling strategies.

    NARCIS (Netherlands)

    Breemen, van N.

    1995-01-01

    This paper briefly reviews pathways by which plants can influence the nutrient cycle, and thereby the nutrient supply of themselves and of their competitors. Higher or lower internal nutrient use efficiency positively feeds back into the nutrient cycle, and helps to increase or decrease soil

  5. Universal cycle periods

    NARCIS (Netherlands)

    Groot, de E.A. (Bert); Franses, P.H.P.H.

    2009-01-01

    We present a meta-analysis of cycles in historical economic data. The literature on stochastic and deterministic cycles in variables such as the consumer price index, employment, interest rates, commodity prices, and GDP is huge and scattered, but our meta-analysis reveals various communalities. Our

  6. New device to measure dynamic intrusion/extrusion cycles of lyophobic heterogeneous systems.

    Science.gov (United States)

    Guillemot, Ludivine; Galarneau, Anne; Vigier, Gérard; Abensur, Thierry; Charlaix, Élisabeth

    2012-10-01

    Lyophobic heterogeneous systems (LHS) are made of mesoporous materials immersed in a non-wetting liquid. One application of LHS is the nonlinear damping of high frequency vibrations. The behaviour of LHS is characterized by P - ΔV cycles, where P is the pressure applied to the system, and ΔV its volume change due to the intrusion of the liquid into the pores of the material, or its extrusion out of the pores. Very few dynamic studies of LHS have been performed until now. We describe here a new apparatus that allows us to carry out dynamic intrusion/extrusion cycles with various liquid/porous material systems, controlling the temperature from ambient to 120 °C and the frequency from 0.01 to 20 Hz. We show that for two LHS: water/MTS and Galinstan/CPG, the energy dissipated during one cycle depends very weakly on the cycle frequency, in strong contrast to conventional dampers.

  7. Primary water chemistry optimization for extended fuel cycle operation. Results of the 'Duo experimentation' after three cycles

    Energy Technology Data Exchange (ETDEWEB)

    Viricel, L.; Andrieu, C.; Segura, J.C.; Rocher, A. [Electricite de France (France); Thomazet, J.; Clinard, M.H. [Framatome ANP (France); Dacquait, F. [Commissariat a l' Energie Atomique (France)

    2002-07-01

    The primary coolant conditioning in French nuclear power plants is essentially based on the boron-lithium coordinated chemistry, with a target pH of 7.2 at 300 C and a maximum lithium concentration of 2.2 mg/kg. In 1996, EDF 1300 MWe units began operating 18-month fuel cycles, increasing boron concentrations at the beginning of the cycles. Since today the maximum lithium concentration in normal operation is 2.2 mg/kg, extended cycle operation results in a decrease in the pH at the beginning of the cycles, which may possibly lead to deposits in RCS, and particularly on the fuel cladding, and increased dose rates. It has to be noted that today, the fuel assemblies maximum burnup is set at 52 GWd/tU. One solution is to adjust the pH by increasing the lithium content at the beginning of the cycles, which is easy to implement and does not require any modification on the units. Hence, EDF is testing a ''modified'' chemistry regime in the << Duo experimentation >> during 4 fuel cycles, with a maximum authorized lithium content of 3.5 mg/kg at the beginning of the cycles in the Cattenom 2 pilot unit. The Golfech 1 reference unit implements a standard boron-lithium coordination pH{sub 300} 7.2. The major goal of the experimentation is to assess the impact of elevated lithium concentrations at the beginning of the cycles on fuel cladding oxide behavior, mass transport and dose rates. This paper presents the results of the first three cycles of the Duo experimentation. (author)

  8. Predicting the start and maximum amplitude of solar cycle 24 using similar phases and a cycle grouping

    International Nuclear Information System (INIS)

    Wang Jialong; Zong Weiguo; Le Guiming; Zhao Haijuan; Tang Yunqiu; Zhang Yang

    2009-01-01

    We find that the solar cycles 9, 11, and 20 are similar to cycle 23 in their respective descending phases. Using this similarity and the observed data of smoothed monthly mean sunspot numbers (SMSNs) available for the descending phase of cycle 23, we make a date calibration for the average time sequence made of the three descending phases of the three cycles, and predict the start of March or April 2008 for cycle 24. For the three cycles, we also find a linear correlation of the length of the descending phase of a cycle with the difference between the maximum epoch of this cycle and that of its next cycle. Using this relationship along with the known relationship between the rise-time and the maximum amplitude of a slowly rising solar cycle, we predict the maximum SMSN of cycle 24 of 100.2 ± 7.5 to appear during the period from May to October 2012. (letters)

  9. The IAEA activities supporting implementation of best practice in uranium production cycle

    International Nuclear Information System (INIS)

    Slezak, J.

    2010-01-01

    'Full text:' Since the International Atomic Energy Agency's foundation in 1957, the Agency has had an increasing interest in uranium production cycle (UPC) developments. Recent activities cover tasks on uranium geology & deposits, exploration, mining & processing including environmental issues. The two projects titles are (1) Updating uranium resources, supply and demand and nuclear fuel cycle databases and (2) Supporting good practices in the UPC in particular for new countries. Based o the recent experience, one of the new activities is focused at human resources development to improve application of best practice called Uranium Production Cycle Network (UPNet). (author)

  10. Associations between urban form and cycling

    DEFF Research Database (Denmark)

    Nielsen, Thomas Alexander Sick; Olafsson, Anton Stahl; Carstensen, Trine Agervig

    of National Travel Survey data indicated that established walkability factors such as density, connectivity and diversity are related to cycling, and that access to retail concentrations/centres, public transportation level-of-service, as well as competition between walking and cycling depending...... of cycling and the distance cycled. A high probability of cycling generally implies short cycling distances, which leads to non-uniform, non-monotonous relations between environmental indicators such as walkability and total cycling. Further analysis of primary data allowing a consideration of attitudes...

  11. Characterizing cycle-to-cycle variations of the shedding cycle in the turbulent wake of a normal flat plate using generalized phase averages

    Science.gov (United States)

    Martinuzzi, Robert

    2016-11-01

    Quasi-periodic vortex shedding in the turbulent wake of a thin-flat plate placed normal to a uniform stream at Reynolds number of 6700 is investigated based on Particle Image Velocimetry experiments. The wake structure and vortex formation are characterized using a generalized phase average (GPA), a refinement of the triple decomposition of Reynolds and Hussain (1970) incorporating elements of mean-field theory (Stuart, 1958). The resulting analysis highlights the importance of cycle-to-cycle variations in characterizing vortex formation, wake topology and the residual turbulent Reynolds Stresses. For example, it is shown that during high-amplitude cycles vorticity is strongly concentrated within the well-organized shed vortices, whereas during low-amplitude cycles the shed vortices are highly distorted resulting in significant modulation of the shedding frequency. It is found that high-amplitude cycles contribute more to the coherent Reynolds stress field while the low-amplitude cycles contribute to the residual stress field. It is further shown that traditional phase-averaging techniques lead to an over-estimation of the residual stress field. Natural Sciences and Engineering Research Council of Canada.

  12. Closed-cycle gas turbine working fluids

    International Nuclear Information System (INIS)

    Lee, J.C.; Campbell, J. Jr.; Wright, D.E.

    1981-01-01

    Characteristic requirements of a closed-cycle gas turbine (CCGT) working fluid were identified and the effects of their thermodynamic and transport properties on the CCGT cycle performance, required heat exchanger surface area and metal operating temperature, cycle operating pressure levels, and the turbomachinery design were investigated. Material compatibility, thermal and chemical stability, safety, cost, and availability of the working fluid were also considered in the study. This paper also discusses CCGT working fluids utilizing mixtures of two or more pure gases. Some mixtures of gases exhibit pronounced synergetic effects on their characteristic properties including viscosity, thermal conductivity and Prandtl number, resulting in desirable heat transfer properties and high molecular weights. 21 refs

  13. Engine performances and exhaust gas characteristics of methanol-fueled two-cycle engines. Kogata ni cycle ter dot methanol kikan no seino ni oyobosu shoinshi no eikyo

    Energy Technology Data Exchange (ETDEWEB)

    Sawa, N.; Kajitani, S. (Ibaraki Univ., Ibaraki (Japan). Faculty of Engineerineering); Hayashi, S.; Kubota, Y. (Muroran Inst. of Technology, Muroran (Japan))

    1990-10-25

    Regarding crank case compressed two cycle engine, feasibility of methanol-fueled engine was investigated by studying effective factors on properties of power, combustion, and exhaust gas. For the experiment, air-cooling single cylinder engine was used of which specification was shown by table. As for the experiment, quantities of in-taken air, fuel consumption, torque, and composition of exhaust gas were measured under various conditions. As the consideration of experimental results, those were obtained that less exhaust gas with high performance operation of tow-cycle engie was achieved, too, by using diluted mixture gas of methanol, and that problems were found to be studied for the realization of high compression ratio. 12 refs., 13 figs., 1 tab.

  14. Stability through cycles

    NARCIS (Netherlands)

    E.A. de Groot (Bert); Ph.H.B.F. Franses (Philip Hans)

    2006-01-01

    textabstractEconomic variables like GDP growth, employment, interest rates and consumption show signs of cyclical behavior. Many variables display multiple cycles, with lengths ranging in between 5 to even up to 100 years. We argue that multiple cycles can be associated with long-run stability of

  15. Economics analysis of fuel cycle cost of fusion–fission hybrid reactors based on different fuel cycle strategies

    Energy Technology Data Exchange (ETDEWEB)

    Zu, Tiejun, E-mail: tiejun@mail.xjtu.edu.cn; Wu, Hongchun; Zheng, Youqi; Cao, Liangzhi

    2015-01-15

    Highlights: • Economics analysis of fuel cycle cost of FFHRs is carried out. • The mass flows of different fuel cycle strategies are established based on the equilibrium fuel cycle model. • The levelized fuel cycle costs of different fuel cycle strategies are calculated, and compared with current once-through fuel cycle. - Abstract: The economics analysis of fuel cycle cost of fusion–fission hybrid reactors has been performed to compare four fuel cycle strategies: light water cooled blanket burning natural uranium (Strategy A) or spent nuclear fuel (Strategy B), sodium cooled blanket burning transuranics (Strategy C) or minor actinides (Strategy D). The levelized fuel cycle costs (LFCC) which does not include the capital cost, operation and maintenance cost have been calculated based on the equilibrium mass flows. The current once-through (OT) cycle strategy has also been analyzed to serve as the reference fuel cycle for comparisons. It is found that Strategy A and Strategy B have lower LFCCs than OT cycle; although the LFCC of Strategy C is higher than that of OT cycle when the uranium price is at its nominal value, it would become comparable to that of OT cycle when the uranium price reaches its historical peak value level; Strategy D shows the highest LFCC, because it needs to reprocess huge mass of spent nuclear fuel; LFCC is sensitive to the discharge burnup of the nuclear fuel.

  16. HTGR fuel and fuel cycle technology

    International Nuclear Information System (INIS)

    Lotts, A.L.; Coobs, J.H.

    1976-08-01

    The status of fuel and fuel cycle technology for high-temperature gas-cooled reactors (HTGRs) is reviewed. The all-ceramic core of the HTGRs permits high temperatures compared with other reactors. Core outlet temperatures of 740 0 C are now available for the steam cycle. For advanced HTGRs such as are required for direct-cycle power generation and for high-temperature process heat, coolant temperatures as high as 1000 0 C may be expected. The paper discusses the variations of HTGR fuel designs that meet the performance requirements and the requirements of the isotopes to be used in the fuel cycle. Also discussed are the fuel cycle possibilities, which include the low-enrichment cycle, the Th- 233 U cycle, and plutonium utilization in either cycle. The status of fuel and fuel cycle development is summarized

  17. Cell cycle phases in the unequal mother/daughter cell cycles of Saccharomyces cerevisiae.

    Science.gov (United States)

    Brewer, B J; Chlebowicz-Sledziewska, E; Fangman, W L

    1984-11-01

    During cell division in the yeast Saccharomyces cerevisiae mother cells produce buds (daughter cells) which are smaller and have longer cell cycles. We performed experiments to compare the lengths of cell cycle phases in mothers and daughters. As anticipated from earlier indirect observations, the longer cell cycle time of daughter cells is accounted for by a longer G1 interval. The S-phase and the G2-phase are of the same duration in mother and daughter cells. An analysis of five isogenic strains shows that cell cycle phase lengths are independent of cell ploidy and mating type.

  18. Glutamatergic and GABAergic TCA cycle and neurotransmitter cycling fluxes in different regions of mouse brain.

    Science.gov (United States)

    Tiwari, Vivek; Ambadipudi, Susmitha; Patel, Anant B

    2013-10-01

    The (13)C nuclear magnetic resonance (NMR) studies together with the infusion of (13)C-labeled substrates in rats and humans have provided important insight into brain energy metabolism. In the present study, we have extended a three-compartment metabolic model in mouse to investigate glutamatergic and GABAergic tricarboxylic acid (TCA) cycle and neurotransmitter cycle fluxes across different regions of the brain. The (13)C turnover of amino acids from [1,6-(13)C2]glucose was monitored ex vivo using (1)H-[(13)C]-NMR spectroscopy. The astroglial glutamate pool size, one of the important parameters of the model, was estimated by a short infusion of [2-(13)C]acetate. The ratio Vcyc/VTCA was calculated from the steady-state acetate experiment. The (13)C turnover curves of [4-(13)C]/[3-(13)C]glutamate, [4-(13)C]glutamine, [2-(13)C]/[3-(13)C]GABA, and [3-(13)C]aspartate from [1,6-(13)C2]glucose were analyzed using a three-compartment metabolic model to estimate the rates of the TCA cycle and neurotransmitter cycle associated with glutamatergic and GABAergic neurons. The glutamatergic TCA cycle rate was found to be highest in the cerebral cortex (0.91 ± 0.05 μmol/g per minute) and least in the hippocampal region (0.64 ± 0.07 μmol/g per minute) of the mouse brain. In contrast, the GABAergic TCA cycle flux was found to be highest in the thalamus-hypothalamus (0.28 ± 0.01 μmol/g per minute) and least in the cerebral cortex (0.24 ± 0.02 μmol/g per minute). These findings indicate that the energetics of excitatory and inhibitory function is distinct across the mouse brain.

  19. Digital calculations of engine cycles

    CERN Document Server

    Starkman, E S; Taylor, C Fayette

    1964-01-01

    Digital Calculations of Engine Cycles is a collection of seven papers which were presented before technical meetings of the Society of Automotive Engineers during 1962 and 1963. The papers cover the spectrum of the subject of engine cycle events, ranging from an examination of composition and properties of the working fluid to simulation of the pressure-time events in the combustion chamber. The volume has been organized to present the material in a logical sequence. The first two chapters are concerned with the equilibrium states of the working fluid. These include the concentrations of var

  20. A comparison study on radioactive waste management effectiveness in various nuclear fuel cycles

    International Nuclear Information System (INIS)

    Ko, Won Il; Kim, Ho Dong

    2001-07-01

    This study examines whether the DUPIC (Direct Use of Spent PWR Fuel In CANDU) fuel cycle make radioactive waste management more effective, by comparing it with other fuel cycles such as the PWR (Pressurized Water Reactor) once-through cycle, the HWR (Pressurized Heavy Water Reactor) once-through cycle and the thermal recycling option to use an existing PWR with MOX (Mixed Oxide) fuel. This study first focuses on the radioactive waste volume generated in all fuel cycle steps, which could be one of the measures of effectiveness of the waste management. Then the total radioactive waste disposition cost is estimated based on two units measuring; m3/GWe-yr and US$/GWe-yr. We find from the radioactive waste volume estimation that the DUPIC fuel cycle could have lower volumes for milling tailings, low level waste and spent fuel than those of other fuel cycle options. From the results of the disposition cost analysis, we find that the DUPIC waste disposition cost is the lowest among fuel cycle options. If the total waste disposition cost is used as a proxy for quantifying the easiness or difficulty in managing wastes, then the DUPIC option actually make waste management easier

  1. Development of an improved two-cycle process for recovering uranium from wet-process phosphoric acid

    International Nuclear Information System (INIS)

    Chen, H.M.; Chen, H.J.; Tsai, Y.M.; Lee, T.W.; Ting, G.

    1987-01-01

    An improved two-cycle separation process for the recovery of uranium from wet-process phosphoric acid by extraction with bis(2-ethylhexyl)phosphoric acid (D2EHPA) plus dibutyl butylphosphonate (DBBP) in kerosene has been developed and demonstrated successfully in bench-scale, continuous mixer-settler tests. The sulfuric acid and water scrubbing steps for the recycled extraction in the second cycle solve the problems of the contamination and dilution of the phosphoric acid by the ammonium ion and water and also avoid the formation of undesirable phosphatic precipitates during the subsequent extraction of uranium by recycled organic extractant

  2. Cell growth and division cycle

    International Nuclear Information System (INIS)

    Darzynkiewicz, Z.

    1986-01-01

    The concept of the cell cycle in its present form was introduced more than three decades ago. Studying incorporation of DNA precursors by autoradiography, these authors observed that DNA synthesis in individual cells was discontinuous and occupied a discrete portion of the cell life (S phase). Mitotic division was seen to occur after a certain period of time following DNA replication. A distinct time interval between mitosis and DNA replication was also apparent. Thus, the cell cycle was subdivided into four consecutive phases, G/sub 1/, S, G/sub 2/, and M. The G/sub 1/ and G/sub 2/ phases represented the ''gaps'' between mitosis and the start of DNA replication, and between the end of DNA replication and the onset of mitosis, respectively. The cell cycle was defined as the interval between the midpoint of mitosis and the midpoint of the subsequent mitosis of the daughter cell(s). The authors' present knowledge on the cell cycle benefited mostly from the development of four different techniques: autoradiography, time-lapse cinematography, cell synchronization and flow cytometry. Of these, autoradiography has been the most extensively used, especially during the past two decades. By providing a means to analyse incorporation of precursors of DNA, RNA or proteins by individual cells and, in combination with various techniques of cell synchronization, autoradiography yielded most of the data fundamental to the current understanding of the cell cycle-related phenomena. Kinetics of cell progression through the cell cycle could be analysed in great detail after development of such sophisticated autoradiographic approaches as measurements of the fraction of labeled mitoses (''FLM curves'') or multiple sequential cell labelling with /sup 3/H- and /sup 14/C-TdR

  3. An integrated life cycle inventory for demolition processes in the context of life cycle sustainability assessment

    DEFF Research Database (Denmark)

    Bozhilova-Kisheva, Kossara Petrova; Hu, Mingming; van Roekel, Eric

    2012-01-01

    According to the Life Cycle Assessment in Building and Construction: State-of-the-Art Report (2003), the dismantling and demolition stage of the building life cycle is only sometimes included in the Life Cycle Inventory (LCI) when doing Life Cycle Assessments (LCA). The reason that it is less...... inventoried in a traditional LCA maybe because this stage is expected to have a negligible environmental impact comparing to other stages in the life cycle of the buildings. When doing a life cycle sustainability assessment considering not only environmental but also economic and social impacts, the impacts...

  4. A framework for social life cycle impact assessment

    DEFF Research Database (Denmark)

    Dreyer, Louise Camilla; Hauschild, Michael Zwicky; Schierbeck, Jens

    2006-01-01

    Goal, Scope and Background. To enhance the use of life cycle assessment (LCA) as a tool in business decision-making, a methodology for Social life cycle impact assessment (LCIA) is being developed. Social LCA aims at facilitating companies to conduct business in a socially responsible manner...... by providing information about the potential social impacts on people caused by the activities in the life cycle of their product. The development of the methodology has been guided by a business perspective accepting that companies, on the one hand, have responsibility for the people affected...... in the life cycle rather than to the individual industrial processes, as is the case in Environmental LCA. Inventory analysis is therefore focused on the conduct of the companies engaged in the life cycle. A consequence of this view is that a key must be determined for relating the social profiles...

  5. Fatigue during maximal sprint cycling: unique role of cumulative contraction cycles.

    Science.gov (United States)

    Tomas, Aleksandar; Ross, Emma Z; Martin, James C

    2010-07-01

    Maximal cycling power has been reported to decrease more rapidly when performed with increased pedaling rates. Increasing pedaling rate imposes two constraints on the neuromuscular system: 1) decreased time for muscle excitation and relaxation and 2) increased muscle shortening velocity. Using two crank lengths allows the effects of time and shortening velocity to be evaluated separately. We conducted this investigation to determine whether the time available for excitation and relaxation or the muscle shortening velocity was mainly responsible for the increased rate of fatigue previously observed with increased pedaling rates and to evaluate the influence of other possible fatiguing constraints. Seven trained cyclists performed 30-s maximal isokinetic cycling trials using two crank lengths: 120 and 220 mm. Pedaling rate was optimized for maximum power for each crank length: 135 rpm for the 120-mm cranks (1.7 m x s(-1) pedal speed) and 109 rpm for the 220-mm cranks (2.5 m x s(-1) pedal speed). Power was recorded with an SRM power meter. Crank length did not affect peak power: 999 +/- 276 W for the 120-mm crank versus 1001 +/- 289 W for the 220-mm crank. Fatigue index was greater (58.6% +/- 3.7% vs 52.4% +/- 4.8%, P < 0.01), and total work was less (20.0 +/- 1.8 vs 21.4 +/- 2.0 kJ, P < 0.01) with the higher pedaling rate-shorter crank condition. Regression analyses indicated that the power for the two conditions was most highly related to cumulative work (r2 = 0.94) and to cumulative cycles (r2 = 0.99). These results support previous findings and confirm that pedaling rate, rather than pedal speed, was the main factor influencing fatigue. Our novel result was that power decreased by a similar increment with each crank revolution for the two conditions, indicating that each maximal muscular contraction induced a similar amount of fatigue.

  6. A comparison of advanced heat recovery power cycles in a combined cycle for large ships

    DEFF Research Database (Denmark)

    Larsen, Ulrik; Sigthorsson, Oskar; Haglind, Fredrik

    2014-01-01

    Strong motivation exists within the marine sector to reduce fuel expenses and to comply with ever stricter emission regulations. Heat recovery can address both of these issues. The ORC (organic Rankine cycle), the Kalina cycle and the steam Rankine cycle have received the majority of the focus...... fluids possess high global warming potentials and hazard levels. It is concluded that the ORC has the greatest potential for increasing the fuel efficiency, and the combined cycle offers very high thermal efficiency. While being less efficient, the steam cycle has the advantages of being well proven...

  7. Natural cycle in vitro fertilisation (IVF) for subfertile couples.

    Science.gov (United States)

    Allersma, Thomas; Farquhar, Cindy; Cantineau, Astrid E P

    2013-08-30

    Subfertility affects 15% to 20% of couples trying to conceive. In vitro fertilisation (IVF) is one of the assisted reproduction techniques developed to improve chances of achieving pregnancy. In the standard IVF method with controlled ovarian hyperstimulation (COH), growth and development of multiple follicles are stimulated by using gonadotrophins, often combined with a gonadotrophin-releasing hormone (GnRH) agonist or antagonist. Although it is an established method of conception for subfertile couples, the treatment is expensive and has a high risk of adverse effects. Studies have shown that IVF in a natural cycle (NC) or a modified natural cycle (MNC) might be a promising low risk and low cost alternative to the standard stimulated IVF treatment since the available dominant follicle of each cycle is used. In this review, we included available randomised controlled studies comparing natural cycle IVF (NC and MNC) with standard IVF. To compare the efficacy and safety of natural cycle IVF (including both NC-IVF and MNC-IVF) with controlled ovarian hyperstimulation IVF (COH-IVF) in subfertile couples. An extended search including of the Menstrual Disorders and Subfertility Group (MDSG) Specialised Register, Cochrane Central Register of Controlled Trials (CENTRAL), MEDLINE, EMBASE, ClinicalTrials.gov, conference abstracts in the Web of Knowledge, the World Health Organization International Trials Registry Platform search portal, LILACS database, PubMed and the OpenSIGLE database was conducted according to Cochrane guidelines. The last search was on 31st July 2013. All randomised controlled trials (RCTs) comparing either natural cycle IVF or modified natural cycle IVF versus standard IVF in subfertile couples were included. Data selection and extraction and risk of bias assessment were carried out independently by two authors (TA and AC). The primary outcome measures were live birth rate and ovarian hyperstimulation syndrome (OHSS) rate per randomised woman. We

  8. Progesterone and women's anxiety across the menstrual cycle.

    Science.gov (United States)

    Reynolds, Tania A; Makhanova, Anastasia; Marcinkowska, Urszula M; Jasienska, Grazyna; McNulty, James K; Eckel, Lisa A; Nikonova, Larissa; Maner, Jon K

    2018-04-24

    Animal models and a few human investigations suggest progesterone may be associated with anxiety. Progesterone naturally fluctuates across the menstrual cycle, offering an opportunity to understand how within-person increases in progesterone and average progesterone levels across the cycle correspond to women's anxiety. Across two longitudinal studies, we simultaneously modeled the between- and within-person associations between progesterone and anxiety using multilevel modeling. In Study 1, 100 Polish women provided saliva samples and reported their anxiety at three phases of the menstrual cycle: follicular, peri-ovulatory, and luteal. A significant between-person effect emerged, revealing that women with higher average progesterone levels across their cycles reported higher levels of anxiety than women with lower progesterone cycles. This effect held controlling for estradiol. In Study 2, 61 American women provided saliva samples and reported their attachment anxiety during laboratory sessions during the same three cycle phases. A significant between-person and within-person association emerged: women with higher average progesterone levels reported higher levels of attachment anxiety, and as women's progesterone levels increased across their cycles, so too did their attachment anxiety. These effects held controlling for cortisol. In sum, both studies provide support for a link between menstrual cycle progesterone levels and subjective anxiety. Copyright © 2018. Published by Elsevier Inc.

  9. Wi-Fi Coexistence with Duty Cycled LTE-U

    Directory of Open Access Journals (Sweden)

    Yimin Pang

    2017-01-01

    Full Text Available Coexistence of Wi-Fi and LTE-Unlicensed (LTE-U technologies has drawn significant concern in industry. In this paper, we investigate the Wi-Fi performance in the presence of duty cycle based LTE-U transmission on the same channel. More specifically, one LTE-U cell and one Wi-Fi basic service set (BSS coexist by allowing LTE-U devices to transmit their signals only in predetermined duty cycles. Wi-Fi stations, on the other hand, simply contend the shared channel using the distributed coordination function (DCF protocol without cooperation with the LTE-U system or prior knowledge about the duty cycle period or duty cycle of LTE-U transmission. We define the fairness of the above scheme as the difference between Wi-Fi performance loss ratio (considering a defined reference performance and the LTE-U duty cycle (or function of LTE-U duty cycle. Depending on the interference to noise ratio (INR being above or below −62 dbm, we classify the LTE-U interference as strong or weak and establish mathematical models accordingly. The average throughput and average service time of Wi-Fi are both formulated as functions of Wi-Fi and LTE-U system parameters using probability theory. Lastly, we use the Monte Carlo analysis to demonstrate the fairness of Wi-Fi and LTE-U air time sharing.

  10. Effect of war on the menstrual cycle.

    Science.gov (United States)

    Hannoun, Antoine B; Nassar, Anwar H; Usta, Ihab M; Zreik, Tony G; Abu Musa, Antoine A

    2007-04-01

    To study the effect of a short period of war on the menstrual cycles of exposed women. Six months after a 16-day war, women in exposed villages aged 15-45 years were asked to complete a questionnaire relating to their menstrual history at the beginning, 3 months after, and 6 months after the war. A control group, not exposed to war, was also interviewed. The data collected were analyzed to estimate the effect of war on three groups of women: those who stayed in the war zone for 3-16 days (Group A), those who were displaced within 2 days to safer areas (Group B), and women not exposed to war or displacement (Group C-control). More than 35% of women in Group A and 10.5% in Group B had menstrual aberrations 3 months after the cessation of the war. These percentages were significantly different from each other and from that in Group C (2.6%). Six months after the war most women regained their regular menstrual cycles with the exception of 18.6% in Group A. We found a short period of war, acting like an acute stressful condition, resulted in menstrual abnormalities in 10-35% of women and is probably related to the duration of exposure to war. This might last beyond the war time and for more than one or two cycles. In most women the irregular cycles reversed without any medical intervention. II.

  11. Changes in oscillatory dynamics in the cell cycle of early Xenopus laevis embryos.

    Directory of Open Access Journals (Sweden)

    Tony Y-C Tsai

    2014-02-01

    Full Text Available During the early development of Xenopus laevis embryos, the first mitotic cell cycle is long (∼85 min and the subsequent 11 cycles are short (∼30 min and clock-like. Here we address the question of how the Cdk1 cell cycle oscillator changes between these two modes of operation. We found that the change can be attributed to an alteration in the balance between Wee1/Myt1 and Cdc25. The change in balance converts a circuit that acts like a positive-plus-negative feedback oscillator, with spikes of Cdk1 activation, to one that acts like a negative-feedback-only oscillator, with a shorter period and smoothly varying Cdk1 activity. Shortening the first cycle, by treating embryos with the Wee1A/Myt1 inhibitor PD0166285, resulted in a dramatic reduction in embryo viability, and restoring the length of the first cycle in inhibitor-treated embryos with low doses of cycloheximide partially rescued viability. Computations with an experimentally parameterized mathematical model show that modest changes in the Wee1/Cdc25 ratio can account for the observed qualitative changes in the cell cycle. The high ratio in the first cycle allows the period to be long and tunable, and decreasing the ratio in the subsequent cycles allows the oscillator to run at a maximal speed. Thus, the embryo rewires its feedback regulation to meet two different developmental requirements during early development.

  12. Entrainment of Spontaneously Hypertensive Rat Fibroblasts by Temperature Cycles

    Science.gov (United States)

    Sládek, Martin; Sumová, Alena

    2013-01-01

    The functional state of the circadian system of spontaneously hypertensive rats (SHR) differs in several characteristics from the functional state of normotensive Wistar rats. Some of these changes might be due to the compromised ability of the central pacemaker to entrain the peripheral clocks. Daily body temperature cycles represent one of the important cues responsible for the integrity of the circadian system, because these cycles are driven by the central pacemaker and are able to entrain the peripheral clocks. This study tested the hypothesis that the aberrant peripheral clock entrainment of SHR results from a compromised peripheral clock sensitivity to the daily temperature cycle resetting. Using cultured Wistar rat and SHR fibroblasts transfected with the circadian luminescence reporter Bmal1-dLuc, we demonstrated that two consecutive square-wave temperature cycles with amplitudes of 2.5°C are necessary and sufficient to restart the dampened oscillations and entrain the circadian clocks in both Wistar rat and SHR fibroblasts. We also generated a phase response curve to temperature cycles for fibroblasts of both rat strains. Although some of the data suggested a slight resistance of SHR fibroblasts to temperature entrainment, we concluded that the overall effect it too weak to be responsible for the differences between the SHR and Wistar in vivo circadian phenotype. PMID:24116198

  13. The influence of diffusion absorption refrigeration cycle configuration on the performance

    International Nuclear Information System (INIS)

    Zohar, A.; Jelinek, M.; Levy, A.; Borde, I.

    2007-01-01

    Based on a full thermodynamic model for ammonia-water diffusion absorption refrigeration (DAR) cycle with hydrogen as the auxiliary inert gas, the performance of two fundamental configurations of a DAR cycle, with and without condensate sub-cooling prior to the evaporator entrance, were studied and compared. The performances of the two cycles were examined parametrically by computer simulations. Mass and energy conservation equations were developed for each component of the cycles and solved numerically. It was found that the DAR cycle without condensate sub-cooling shows higher COP of 14-20% in compare with the DAR cycle with the condensate sub-cooling, but it occurs at higher evaporator temperature of about 15 deg. C

  14. Verifiable Fuel Cycle Simulation Model (VISION): A Tool for Analyzing Nuclear Fuel Cycle Futures

    International Nuclear Information System (INIS)

    Jacobson, Jacob J.; Piet, Steven J.; Matthern, Gretchen E.; Shropshire, David E.; Jeffers, Robert F.; Yacout, A.M.; Schweitzer, Tyler

    2010-01-01

    The nuclear fuel cycle consists of a set of complex components that are intended to work together. To support the nuclear renaissance, it is necessary to understand the impacts of changes and timing of events in any part of the fuel cycle system such as how the system would respond to each technological change, a series of which moves the fuel cycle from where it is to a postulated future state. The system analysis working group of the United States research program on advanced fuel cycles (formerly called the Advanced Fuel Cycle Initiative) is developing a dynamic simulation model, VISION, to capture the relationships, timing, and changes in and among the fuel cycle components to help develop an understanding of how the overall fuel cycle works. This paper is an overview of the philosophy and development strategy behind VISION. The paper includes some descriptions of the model components and some examples of how to use VISION. For example, VISION users can now change yearly the selection of separation or reactor technologies, the performance characteristics of those technologies, and/or the routing of material among separation and reactor types - with the model still operating on a PC in <5 min.

  15. Part 5. Fuel cycle options

    International Nuclear Information System (INIS)

    Lineberry, M.J.; McFarlane, H.F.; Amundson, P.I.; Goin, R.W.; Webster, D.S.

    1980-01-01

    The results of the FBR fuel cycle study that supported US contributions to the INFCE are presented. Fuel cycle technology is reviewed from both generic and historical standpoints. Technology requirements are developed within the framework of three deployment scenarios: the reference international, the secured area, and the integral cycle. Reprocessing, fabrication, waste handling, transportation, and safeguards are discussed for each deployment scenario. Fuel cycle modifications designed to increase proliferation defenses are described and assessed for effectiveness and technology feasibility. The present status of fuel cycle technology is reviewed and key issues that require resolution are identified

  16. Cell-cycle synchronisation of bloodstream forms of Trypanosoma brucei using Vybrant DyeCycle Violet-based sorting.

    Science.gov (United States)

    Kabani, Sarah; Waterfall, Martin; Matthews, Keith R

    2010-01-01

    Studies on the cell-cycle of Trypanosoma brucei have revealed several unusual characteristics that differ from the model eukaryotic organisms. However, the inability to isolate homogenous populations of parasites in distinct cell-cycle stages has limited the analysis of trypanosome cell division and complicated the understanding of mutant phenotypes with possible impact on cell-cycle related events. Although hydroxyurea-induced cell-cycle arrest in procyclic and bloodstream forms has been applied recently with success, such block-release protocols can complicate the analysis of cell-cycle regulated events and have the potential to disrupt important cell-cycle checkpoints. An alternative approach based on flow cytometry of parasites stained with Vybrant DyeCycle Orange circumvents this problem, but is restricted to procyclic form parasites. Here, we apply Vybrant Dyecycle Violet staining coupled with flow cytometry to effectively select different cell-cycle stages of bloodstream form trypanosomes. Moreover, the sorted parasites remain viable, although synchrony is rapidly lost. This method enables cell-cycle enrichment of populations of trypanosomes in their mammal infective stage, particularly at the G1 phase.

  17. Predicting product life cycle using fuzzy neural network

    Directory of Open Access Journals (Sweden)

    Ali Mohammadi

    2014-09-01

    Full Text Available One of the most important tasks of science in different fields is to find the relationships among various phenomena in order to predict future. Production and service organizations are not exceptions and they should predict future to survive. Predicting the life cycle of the organization's products is one of the most important prediction cases in an organization. Predicting the product life cycle provides an opportunity to identify the product position and help to get a better insight about competitors. This paper deals with the predictability of the product life cycle with Adaptive Network-Based Fuzzy Inference System (ANFIS. The Population of this study was Pegah Fars products and the sample was this company's cheese products. In this regard, this paper attempts to model and predict the product life cycle of cheese products in Pegah Fars Company. In this due, a designed questionnaire was distributed among some experts, distributors and retailers and seven independent variables were selected. In this survey, ANFIS sales forecasting technique was employed and MATLAB software was used for data analysis. The results confirmed ANFIS as a good method to predict the product life cycle.

  18. Nonautonomous linear system of the terrestrial carbon cycle

    Science.gov (United States)

    Luo, Y.

    2012-12-01

    Carbon cycle has been studied by uses of observation through various networks, field and laboratory experiments, and simulation models. Much less has been done on theoretical thinking and analysis to understand fundament properties of carbon cycle and then guide observatory, experimental, and modeling research. This presentation is to explore what would be the theoretical properties of terrestrial carbon cycle and how those properties can be used to make observatory, experimental, and modeling research more effective. Thousands of published data sets from litter decomposition and soil incubation studies almost all indicate that decay processes of litter and soil organic carbon can be well described by first order differential equations with one or more pools. Carbon pool dynamics in plants and soil after disturbances (e.g., wildfire, clear-cut of forests, and plows of soil for cropping) and during natural recovery or ecosystem restoration also exhibit characteristics of first-order linear systems. Thus, numerous lines of empirical evidence indicate that the terrestrial carbon cycle can be adequately described as a nonautonomous linear system. The linearity reflects the nature of the carbon cycle that carbon, once fixed by photosynthesis, is linearly transferred among pools within an ecosystem. The linear carbon transfer, however, is modified by nonlinear functions of external forcing variables. In addition, photosynthetic carbon influx is also nonlinearly influenced by external variables. This nonautonomous linear system can be mathematically expressed by a first-order linear ordinary matrix equation. We have recently used this theoretical property of terrestrial carbon cycle to develop a semi-analytic solution of spinup. The new methods have been applied to five global land models, including NCAR's CLM and CABLE models and can computationally accelerate spinup by two orders of magnitude. We also use this theoretical property to develop an analytic framework to

  19. GLOBALIZATION VERSUS SEGREGATION - BUSINESS CYCLES SYNCHRONIZATION IN EUROPE

    Directory of Open Access Journals (Sweden)

    Sebastian Florian Enea

    2012-12-01

    Full Text Available Globalization and business cycles are equally elusive economic phenomena; hence they represent a continuous research possibility and a source of possible inquiries due to their complex nature. The aim of the paper is to explain the synchronization of business cycles using the relationship between the growth rate of the GDP and FDI, considered as percentage of the GDP. The results show that there is no unique European business cycle, but two cores between which countries migrate and stress out the importance of the FDI channel in business cycle transmission. The future research directions will employ fuzzy cluster techniques, used on a larger sample.

  20. Economic Analysis of Symbiotic Light Water Reactor/Fast Burner Reactor Fuel Cycles Proposed as Part of the U.S. Advanced Fuel Cycle Initiative (AFCI)

    International Nuclear Information System (INIS)

    Williams, Kent Alan; Shropshire, David E.

    2009-01-01

    A spreadsheet-based 'static equilibrium' economic analysis was performed for three nuclear fuel cycle scenarios, each designed for 100 GWe-years of electrical generation annually: (1) a 'once-through' fuel cycle based on 100% LWRs fueled by standard UO2 fuel assemblies with all used fuel destined for geologic repository emplacement, (2) a 'single-tier recycle' scenario involving multiple fast burner reactors (37% of generation) accepting actinides (Pu,Np,Am,Cm) from the reprocessing of used fuel from the uranium-fueled LWR fleet (63% of generation), and (3) a 'two-tier' 'thermal+fast' recycle scenario where co-extracted U,Pu from the reprocessing of used fuel from the uranium-fueled part of the LWR fleet (66% of generation) is recycled once as full-core LWR MOX fuel (8% of generation), with the LWR MOX used fuel being reprocessed and all actinide products from both UO2 and MOX used fuel reprocessing being introduced into the closed fast burner reactor (26% of generation) fuel cycle. The latter two 'closed' fuel cycles, which involve symbiotic use of both thermal and fast reactors, have the advantages of lower natural uranium requirements per kilowatt-hour generated and less geologic repository space per kilowatt-hour as compared to the 'once-through' cycle. The overall fuel cycle cost in terms of $ per megawatt-hr of generation, however, for the closed cycles is 15% (single tier) to 29% (two-tier) higher than for the once-through cycle, based on 'expected values' from an uncertainty analysis using triangular distributions for the unit costs for each required step of the fuel cycle. (The fuel cycle cost does not include the levelized reactor life cycle costs.) Since fuel cycle costs are a relatively small percentage (10 to 20%) of the overall busbar cost (LUEC or 'levelized unit electricity cost') of nuclear power generation, this fuel cycle cost increase should not have a highly deleterious effect on the competitiveness of nuclear power. If the reactor life cycle

  1. Sun in the Epoch ``LOWERED'' Solar Activity: the Comparative Analysis of the Current 24 Solar Cycle and Past Authentic Low Cycles

    Science.gov (United States)

    Vitaly, Ishkov

    A reliable series of the relative numbers of sunspots (14 solar cycles ‒ 165 years) it leads to the only scenario of solar activity cycles - to the alternation of epochs of “increased” (18 ‒ 22 cycles of solar activity) and “lowered” (12 ‒ 16 and 24 ‒ ...) solar activity with the periods of solar magnetic field reconstruction in solar zone of the sunspots formation (11, 12, 23) from one epoch to another. The regime of the produce of magnetic field significantly changes in these periods, providing to the subsequent 5 cycles the stable conditions of solar activity. Space solar research made it possible to sufficiently fully investigate characteristics and parameters of the solar cycles for the epoch of “increased” (20 ‒ 22 cycles) solar activity and period of the reconstruction (22 ‒ 23 cycles) to the epoch of “lowered” solar activity (24 ‒ ... cycles). In this scenario 24 solar cycle is the first solar cycle of the second epoch of “lowered” solar activity. Therefore his development and characteristics roughly must be described in the context of the low solar cycles development (12, 14, and 16). In the current solar cycle the sunspot-forming activity is lowered, the average areas of the sunspot groups correspond to values for epoch of “lowered “solar activity, average magnetic field in the umbra of sunspots was reduced approximately to 700 gauss, and for this time was observed only 4 very large sunspot groups (≥1500 mvh). Flare activity substantially was lowered: for the time of the current solar cycle development it was occurrence of M-class flares M - 368, class X - 32, from which only 2 solar flares of class X> 5. Solar proton events are observed predominantly small intensity; but only 5 from them were the intensity of ≥100 pfu (S2) and 4 - ≥1000 pfu (S3). The first five years of the 24 cycle evolution confirm this assumption and the possibility to give the qualitative forecast of his evolution and development of the

  2. An analysis of fuel performance cycle 20 of BWR unit 2

    International Nuclear Information System (INIS)

    Hemantha Rao, G.V.S.; Prasad, P.N.; Jayaraj, R.N.

    2008-01-01

    Nuclear Fuel Complex (NFC), an industrial unit of the Department of Atomic Energy (DAE), Government of India manufactures and supplies fuel assemblies to the two Boiling Water Reactors (BWR) at Tarapur Atomic Power Station (TAPS 1 and 2) in India which were commissioned on turnkey collaboration with GE, USA. Each fuel assembly has 36 fuel elements arranged in 6x6 square configuration. Each fuel assembly contains UO 2 pellets of different enrichments. Several improvements have been carried out over the years in the manufacture of fuel assemblies. These changes have helped in improving the fuel performance considerably. During cycle 20, the unit 2 was operating at 506/153 MWth/MWe (95.47% of rated thermal power of 530MWth) prior to shut down for refueling outage. In core sipping was completed within two days. Five leakers were identified during in core sipping. The average leaky assembly's exposure was 16,098.4 MWD/T. The minimum value of a leaky assembly's exposure was 8,591 MWD/T. Out of five assemblies, four assemblies had seen two cycles of exposure and were due for discharge. One assembly had seen single cycle. Trend of chemistry parameters for the last four cycles were within tech spec limits. Similarly trend of physics parameters for the fuel assemblies for the last cycles were also within design/tech spec limits. There were no fuel failures in the previous cycles 18 and 19. The manufacturing and QA details of the five assemblies show no deviations from the procedures and the trends are normal and within specified limits. This paper discusses the analysis of fuel failures in detail

  3. Auditory and visual cueing modulate cycling speed of older adults and persons with Parkinson's disease in a Virtual Cycling (V-Cycle) system.

    Science.gov (United States)

    Gallagher, Rosemary; Damodaran, Harish; Werner, William G; Powell, Wendy; Deutsch, Judith E

    2016-08-19

    Evidence based virtual environments (VEs) that incorporate compensatory strategies such as cueing may change motor behavior and increase exercise intensity while also being engaging and motivating. The purpose of this study was to determine if persons with Parkinson's disease and aged matched healthy adults responded to auditory and visual cueing embedded in a bicycling VE as a method to increase exercise intensity. We tested two groups of participants, persons with Parkinson's disease (PD) (n = 15) and age-matched healthy adults (n = 13) as they cycled on a stationary bicycle while interacting with a VE. Participants cycled under two conditions: auditory cueing (provided by a metronome) and visual cueing (represented as central road markers in the VE). The auditory condition had four trials in which auditory cues or the VE were presented alone or in combination. The visual condition had five trials in which the VE and visual cue rate presentation was manipulated. Data were analyzed by condition using factorial RMANOVAs with planned t-tests corrected for multiple comparisons. There were no differences in pedaling rates between groups for both the auditory and visual cueing conditions. Persons with PD increased their pedaling rate in the auditory (F 4.78, p = 0.029) and visual cueing (F 26.48, p auditory (F = 24.72, p visual cueing (F = 40.69, p visual condition in age-matched healthy adults showed a step-wise increase in pedaling rate (p = 0.003 to p visual cues (p visual cues in order to obtain an increase in cycling intensity. The combination of the VE and auditory cues was neither additive nor interfering. These data serve as preliminary evidence that embedding auditory and visual cues to alter cycling speed in a VE as method to increase exercise intensity that may promote fitness.

  4. Fast breeder fuel cycle

    International Nuclear Information System (INIS)

    1978-09-01

    Basic elements of the ex-reactor part of the fuel cycle (reprocessing, fabrication, waste handling and transportation) are described. Possible technical and proliferation measures are evaluated, including current methods of accountability, surveillance and protection. The reference oxide based cycle and advanced cycles based on carbide and metallic fuels are considered utilizing conventional processes; advanced nonaqueous reprocessing is also considered. This contribution provides a comprehensive data base for evaluation of proliferation risks

  5. Forecast of the key parameters of the 24-th solar cycle

    International Nuclear Information System (INIS)

    Chumak, Oleg Vasilievich; Matveychuk, Tatiana Viktorovna

    2010-01-01

    To predict the key parameters of the solar cycle, a new method is proposed based on the empirical law describing the correlation between the maximum height of the preceding solar cycle and the entropy of the forthcoming one. The entropy of the forthcoming cycle may be estimated using this empirical law, if the maximum height of the current cycle is known. The cycle entropy is shown to correlate well with the cycle's maximum height and, as a consequence, the height of the forthcoming maximum can be estimated. In turn, the correlation found between the height of the maximum and the duration of the ascending branch (the Waldmeier rule) allows the epoch of the maximum, Tmax, to be estimated, if the date of the minimum is known. Moreover, using the law discovered, one can find out the analogous cycles which are similar to the cycle being forecasted, and hence, obtain the synoptic forecast of all main features of the forthcoming cycle. The estimates have shown the accuracy level of this technique to be 86%. The new regularities discovered are also interesting because they are fundamental in the theory of solar cycles and may provide new empirical data. The main parameters of the future solar cycle 24 are as follows: the height of the maximum is Wmax = 95 ± 20, the duration of the ascending branch is Ta = 4.5 ± 0.5yr, the total cycle duration according to the synoptic forecast is 11.3 yr. (research papers)

  6. Solar thermal organic rankine cycle for micro-generation

    Science.gov (United States)

    Alkahli, N. A.; Abdullah, H.; Darus, A. N.; Jalaludin, A. F.

    2012-06-01

    The conceptual design of an Organic Rankine Cycle (ORC) driven by solar thermal energy is developed for the decentralized production of electricity of up to 50 kW. Conventional Rankine Cycle uses water as the working fluid whereas ORC uses organic compound as the working fluid and it is particularly suitable for low temperature applications. The ORC and the solar collector will be sized according to the solar flux distribution in the Republic of Yemen for the required power output of 50 kW. This will be a micro power generation system that consists of two cycles, the solar thermal cycle that harness solar energy and the power cycle, which is the ORC that generates electricity. As for the solar thermal cycle, heat transfer fluid (HTF) circulates the cycle while absorbing thermal energy from the sun through a parabolic trough collector and then storing it in a thermal storage to increase system efficiency and maintains system operation during low radiation. The heat is then transferred to the organic fluid in the ORC via a heat exchanger. The organic fluids to be used and analyzed in the ORC are hydrocarbons R600a and R290.

  7. Carbonate-silicate cycle models of the long-term carbon cycle, carbonate accumulation in the oceans, and climate

    International Nuclear Information System (INIS)

    Caldeira, K.G.

    1991-01-01

    Several models of the long-term carbon cycle, incorporating models of the carbonate-silicate cycle, were developed and utilized to investigate issues relating to global climate and the causes and consequences of changes in calcium carbonate accumulation in the oceans. Model results indicate that the marked mid-Cretaceous (120 Ma) global warming could be explained by increased rates of release of carbon dioxide from subduction-zone metamorphism and mid-ocean-ridges, in conjunction with paleogeographic factors. Since the mid-Cretaceous, the primary setting for calcium carbonate accumulation in the oceans has shifted from shallow-water to deep-water environments. Model results suggest that this shift could have major consequences for the carbonate-silicate cycle and climate, and lead to significant increases in the flux of metamorphic carbon dioxide to the atmosphere. Increases in pelagic carbonate productivity, and decreases in tropical shallow-water area available for neritic carbonate accumulation, have both been proposed as the primary cause of this shift. Two lines of evidence developed here (one involving a statistical analysis of Tertiary carbonate-accumulation and oxygen-isotope data, and another based on modeling the carbonate-silicate cycle and ocean chemistry) suggest that a decrease in tropical shallow-water area was more important than increased pelagic productivity in explaining this shift. Model investigations of changes in ocean chemistry at the Cretaceous/Tertiary (K/T) boundary (66 Ma) indicate that variations in deep-water carbonate productivity may affect shallow-water carbonate accumulation rates through a mechanism involving surface-water carbonate-ion concentration. In the aftermath of the K/T boundary event, deep-water carbonate production and accumulation were significantly reduced as a result of the extinction of calcareous plankton

  8. Neuropsychiatric manifestations in late-onset urea cycle disorder patients

    OpenAIRE

    Serrano Mercedes L.; Martins Cecilia E.; Pérez-Dueñas Belén; Gómez-López Lilian; Murgui Empar; Fons Carmen; García-Cazorla Ángels; Artuch Rafael M D; Jara Fernando; Arranz José Antonio; Häberle Johannes; Briones Paz; Campistol Jaume M D; Pineda Mercè; Vilaseca María Antònia Antonia

    2010-01-01

    Inherited urea cycle disorders represent one of the most common groups of inborn errors of metabolism. Late onset urea cycle disorders caused by partial enzyme deficiencies may present with unexpected clinical phenotypes. We report 9 patients followed up in our hospital presenting late onset urea cycle disorders who initially manifested neuropsychiatric/neurodevelopmental symptoms (the most prevalent neuropsychiatric/neurodevelopmental diagnoses were mental retardation attention deficit hyper...

  9. Prediction of solar cycle 24 using fourier series analysis

    International Nuclear Information System (INIS)

    Khalid, M.; Sultana, M.; Zaidi, F.

    2014-01-01

    Predicting the behavior of solar activity has become very significant. It is due to its influence on Earth and the surrounding environment. Apt predictions of the amplitude and timing of the next solar cycle will aid in the estimation of the several results of Space Weather. In the past, many prediction procedures have been used and have been successful to various degrees in the field of solar activity forecast. In this study, Solar cycle 24 is forecasted by the Fourier series method. Comparative analysis has been made by auto regressive integrated moving averages method. From sources, January 2008 was the minimum preceding solar cycle 24, the amplitude and shape of solar cycle 24 is approximate on monthly number of sunspots. This forecast framework approximates a mean solar cycle 24, with the maximum appearing during May 2014 (+- 8 months), with most sunspot of 98 +- 10. Solar cycle 24 will be ending in June 2020 (+- 7 months). The difference between two consecutive peak values of solar cycles (i.e. solar cycle 23 and 24 ) is 165 months(+- 6 months). (author)

  10. Glassy carbon supercapacitor: 100,000 cycles demonstrated

    Energy Technology Data Exchange (ETDEWEB)

    Baertsch, M; Braun, A; Schnyder, B; Koetz, R [Paul Scherrer Inst. (PSI), Villigen (Switzerland)

    1999-08-01

    A 5 V glassy carbon capacitor stack was built consisting of four bipolar and two end-plate electrodes. More than 100,000 charging/discharging cycles were applied to test the stability of the double-layer capacitor. Low and high frequency resistances were measured as a function of the number of cycles. (author) 2 figs., 1 ref.

  11. Analysis of thermal cycles and working fluids for power generation in space

    International Nuclear Information System (INIS)

    Tarlecki, Jason; Lior, Noam; Zhang Na

    2007-01-01

    Production of power in space for terrestrial use is of great interest in view of the rapidly rising power demand and its environmental impacts. Space also offers a very low temperature, making it a perfect heat sink for power plants, thus offering much higher efficiencies. This paper focuses on the evaluation and analysis of thermal Brayton, Ericsson and Rankine power cycles operating at space conditions on several appropriate working fluids. Under the examined conditions, the thermal efficiency of Brayton cycles reaches 63%, Ericsson 74%, and Rankine 85%. These efficiencies are significantly higher than those for the computed or real terrestrial cycles: by up to 45% for the Brayton, and 17% for the Ericsson; remarkably 44% for the Rankine cycle even when compared with the best terrestrial combined cycles. From the considered working fluids, the diatomic gases (N 2 and H 2 ) produce somewhat better efficiencies than the monatomic ones in the Brayton and Rankine cycles. The Rankine cycles require radiator areas that are larger by up to two orders of magnitude than those required for the Brayton and Ericsson cycles. The results of the analysis of the sensitivity of the cycle performance parameters to major parameters such as turbine inlet temperature and pressure ratio are presented, equations or examining the effects of fluid properties on the radiator area and pressure drop were developed, and the effects of the working fluid properties on cycle efficiency and on the power production per unit radiator area were explored to allow decisions on the optimal choice of working fluids

  12. Performance assessment of simple and modified cycle turboshaft gas turbines

    Directory of Open Access Journals (Sweden)

    Barinyima Nkoi

    2013-06-01

    Full Text Available This paper focuses on investigations encompassing comparative assessment of gas turbine cycle options. More specifically, investigation was carried out of technical performance of turboshaft engine cycles based on existing simple cycle (SC and its projected modified cycles for civil helicopter application. Technically, thermal efficiency, specific fuel consumption, and power output are of paramount importance to the overall performance of gas turbine engines. In course of carrying out this research, turbomatch software established at Cranfield University based on gas turbine theory was applied to conduct simulation of a simple cycle (baseline two-spool helicopter turboshaft engine model with free power turbine. Similarly, some modified gas turbine cycle configurations incorporating unconventional components, such as engine cycle with low pressure compressor (LPC zero-staged, recuperated engine cycle, and intercooled/recuperated (ICR engine cycle, were also simulated. In doing so, design point (DP and off-design point (OD performances of the engine models were established. The percentage changes in performance parameters of the modified cycle engines over the simple cycle were evaluated and it was found that to a large extent, the modified engine cycles with unconventional components exhibit better performances in terms of thermal efficiency and specific fuel consumption than the traditional simple cycle engine. This research made use of public domain open source references.

  13. Recurrent epidemic cycles driven by intervention in a population of two susceptibility types

    International Nuclear Information System (INIS)

    Juanico, Drandreb Earl O

    2014-01-01

    Epidemics have been known to persist in the form of recurrence cycles. Despite intervention efforts through vaccination and targeted social distancing, infectious diseases like influenza continue to appear intermittently over time. I have undertaken an analysis of a stochastic epidemic model to explore the hypothesis that intervention efforts actually drive epidemic cycles. Time series from simulations of the model reveal oscillations exhibiting a similar temporal signature as influenza epidemics. The power-spectral density indicates a resonant frequency, which approximately corresponds to the apparent annual seasonality of influenza in temperate zones. Asymptotic solution to the backward Kolmogorov equation of the dynamics corresponds to an exponentially-decaying mean-exit time as a function of the intervention rate. Intervention must be implemented at a sufficiently high rate to extinguish the infection. The results demonstrate that intervention efforts can induce epidemic cycles, and that the temporal signature of cycles can provide early warning of imminent outbreaks

  14. Cell Cycle Control by PTEN.

    Science.gov (United States)

    Brandmaier, Andrew; Hou, Sheng-Qi; Shen, Wen H

    2017-07-21

    Continuous and error-free chromosome inheritance through the cell cycle is essential for genomic stability and tumor suppression. However, accumulation of aberrant genetic materials often causes the cell cycle to go awry, leading to malignant transformation. In response to genotoxic stress, cells employ diverse adaptive mechanisms to halt or exit the cell cycle temporarily or permanently. The intrinsic machinery of cycling, resting, and exiting shapes the cellular response to extrinsic stimuli, whereas prevalent disruption of the cell cycle machinery in tumor cells often confers resistance to anticancer therapy. Phosphatase and tensin homolog (PTEN) is a tumor suppressor and a guardian of the genome that is frequently mutated or deleted in human cancer. Moreover, it is increasingly evident that PTEN deficiency disrupts the fundamental processes of genetic transmission. Cells lacking PTEN exhibit cell cycle deregulation and cell fate reprogramming. Here, we review the role of PTEN in regulating the key processes in and out of cell cycle to optimize genomic integrity. Copyright © 2017 Elsevier Ltd. All rights reserved.

  15. National Policy on Nuclear Fuel Cycle

    International Nuclear Information System (INIS)

    Soedyartomo, S.

    1996-01-01

    National policy on nuclear fuel cycle is aimed at attaining the expected condition, i.e. being able to support optimality the national energy policy and other related Government policies taking into account current domestic nuclear fuel cycle condition and the trend of international nuclear fuel cycle development, the national strength, weakness, thread and opportunity in the field of energy. This policy has to be followed by the strategy to accomplish covering the optimization of domestic efforts, cooperation with other countries, and or purchasing licences. These policy and strategy have to be broken down into various nuclear fuel cycle programmes covering basically assesment of the whole cycle, performing research and development of the whole cycle without enrichment and reprocessing being able for weapon, as well as programmes for industrialization of the fuel cycle stepwisery commencing with the middle part of the cycle and ending with the edge of the back-end of the cycle

  16. Features of the Phosphatidylinositol Cycle and its Role in Signal Transduction.

    Science.gov (United States)

    Epand, Richard M

    2017-08-01

    The phosphatidylinositol cycle (PI-cycle) has a central role in cell signaling. It is the major pathway for the synthesis of phosphatidylinositol and its phosphorylated forms. In addition, some lipid intermediates of the PI-cycle, including diacylglycerol and phosphatidic acid, are also important lipid signaling agents. The PI-cycle has some features that are important for the understanding of its role in the cell. As a cycle, the intermediates will be regenerated. The PI-cycle requires a large amount of metabolic energy. There are different steps of the cycle that occur in two different membranes, the plasma membrane and the endoplasmic reticulum. In order to complete the PI-cycle lipid must be transferred between the two membranes. The role of the Nir proteins in the process has recently been elucidated. The lipid intermediates of the PI-cycle are normally highly enriched with 1-stearoyl-2-arachidonoyl molecular species in mammals. This enrichment will be retained as long as the intermediates are segregated from other lipids of the cell. However, there is a significant fraction (>15 %) of lipids in the PI-cycle of normal cells that have other acyl chains. Phosphatidylinositol largely devoid of arachidonoyl chains are found in cancer cells. Phosphatidylinositol species with less unsaturation will not be as readily converted to phosphatidylinositol-3,4,5-trisphosphate, the lipid required for the activation of Akt with resulting effects on cell proliferation. Thus, the cyclical nature of the PI-cycle, its dependence on acyl chain composition and its requirement for lipid transfer between two membranes, explain many of the biological properties of this cycle.

  17. Cell Cycle Deregulation in Ewing's Sarcoma Pathogenesis

    Science.gov (United States)

    Kowalewski, Ashley A.; Randall, R. Lor; Lessnick, Stephen L.

    2011-01-01

    Ewing's sarcoma is a highly aggressive pediatric tumor of bone that usually contains the characteristic chromosomal translocation t(11;22)(q24;q12). This translocation encodes the oncogenic fusion protein EWS/FLI, which acts as an aberrant transcription factor to deregulate target genes necessary for oncogenesis. One key feature of oncogenic transformation is dysregulation of cell cycle control. It is therefore likely that EWS/FLI and other cooperating mutations in Ewing's sarcoma modulate the cell cycle to facilitate tumorigenesis. This paper will summarize current published data associated with deregulation of the cell cycle in Ewing's sarcoma and highlight important questions that remain to be answered. PMID:21052502

  18. Cell Cycle Deregulation in Ewing's Sarcoma Pathogenesis

    Directory of Open Access Journals (Sweden)

    Ashley A. Kowalewski

    2011-01-01

    Full Text Available Ewing's sarcoma is a highly aggressive pediatric tumor of bone that usually contains the characteristic chromosomal translocation t(11;22(q24;q12. This translocation encodes the oncogenic fusion protein EWS/FLI, which acts as an aberrant transcription factor to deregulate target genes necessary for oncogenesis. One key feature of oncogenic transformation is dysregulation of cell cycle control. It is therefore likely that EWS/FLI and other cooperating mutations in Ewing's sarcoma modulate the cell cycle to facilitate tumorigenesis. This paper will summarize current published data associated with deregulation of the cell cycle in Ewing's sarcoma and highlight important questions that remain to be answered.

  19. Electric field cycling behavior of ferroelectric hafnium oxide.

    Science.gov (United States)

    Schenk, Tony; Schroeder, Uwe; Pešić, Milan; Popovici, Mihaela; Pershin, Yuriy V; Mikolajick, Thomas

    2014-11-26

    HfO2 based ferroelectrics are lead-free, simple binary oxides with nonperovskite structure and low permittivity. They just recently started attracting attention of theoretical groups in the fields of ferroelectric memories and electrostatic supercapacitors. A modified approach of harmonic analysis is introduced for temperature-dependent studies of the field cycling behavior and the underlying defect mechanisms. Activation energies for wake-up and fatigue are extracted. Notably, all values are about 100 meV, which is 1 order of magnitude lower than for conventional ferroelectrics like lead zirconate titanate (PZT). This difference is mainly atttributed to the one to two orders of magnitude higher electric fields used for cycling and to the different surface to volume ratios between the 10 nm thin films in this study and the bulk samples of former measurements or simulations. Moreover, a new, analog-like split-up effect of switching peaks by field cycling is discovered and is explained by a network model based on memcapacitive behavior as a result of defect redistribution.

  20. Rock Cycle Roulette.

    Science.gov (United States)

    Schmidt, Stan M.; Palmer, Courtney

    2000-01-01

    Introduces an activity on the rock cycle. Sets 11 stages representing the transitions of an earth material in the rock cycle. Builds six-sided die for each station, and students move to the stations depending on the rolling side of the die. Evaluates students by discussing several questions in the classroom. Provides instructional information for…

  1. Lightweight two-stroke cycle aircraft diesel engine technology enablement program, volume 2

    Science.gov (United States)

    Freen, P. D.; Berenyi, S. G.; Brouwers, A. P.; Moynihan, M. E.

    1985-01-01

    An experimental Single Cylinder Test Engine Program is conducted to confirm the analytically projected performance of a two-stroke cycle diesel engine for aircraft applications. Testing confirms the ability of a proposed 4-cylinder version of such an engine to reach the target power at altitude in a highly turbocharged configuration. The experimental program defines all necessary parameters to permit a design of a multicylinder engine for eventual flight applications.

  2. [Effects and mechanism of freeze-thawing cycles on key processes of nitrogen cycle in terrestrial ecosystem].

    Science.gov (United States)

    Wang, Li-qin; Qi, Yu-chun; Dong, Yun-she; Peng, Qin; Guo, Shu-fang; He, Yun-long; Yan, Zhong-qing

    2015-11-01

    As a widespread natural phenomenon in the soil of middle and high latitude as well as high altitude, freeze-thawing cycles have a great influence on the nitrogen cycle of terrestrial ecosystem in non-growing season. Freeze-thawing cycles can alter the physicochemical and biological properties of the soil, which thereby affect the migration and transformation of soil nitrogen. The impacts of freeze-thawing cycles on key processes of nitrogen cycle in terrestrial ecosystem found in available studies remain inconsistent, the mechanism is still not clear, and the research methods also need to be further explored and innovated. So it is necessary to sum up and analyze the existing achievements in order to better understand the processes of soil nitrogen cycle subjected to freeze-thawing cycles. This paper reviewed the research progress in China and abroad about the effects and mechanisms of freeze-thawing cycles on key processes of nitrogen cycle in terrestrial ecosystem, including mineralization, immobilization, nitrification and denitrification, N leakage and gaseous loss, and analyzed the deficiencies of extant research. The possible key research topics that should be urgently paid more attention to in the future were also discussed.

  3. Associations between Recreational and Commuter Cycling, Changes in Cycling, and Type 2 Diabetes Risk

    DEFF Research Database (Denmark)

    Rasmussen, Martin G; Grøntved, Anders; Blond, Kim

    2016-01-01

    BACKGROUND: Cycling is a recreational activity and mode of commuting with substantial potential to improve public health in many countries around the world. The aim of this study was to examine prospective associations between recreational and commuter cycling, changes in cycling habits, and risk.......83 (0.69, 1.00), and 0.70 (0.57, 0.85) (p for trend = 150 min/wk to work, respectively. The main limitation of the current study is the use of self-reported physical activity. CONCLUSIONS: Commuter and recreational cycling was consistently associated with lower...

  4. Changes in International Business Cycle Affiliations

    OpenAIRE

    Erdenebat Bataa; Denise R. Osborn; Marianne Sensier; Dick van Dijk

    2009-01-01

    We investigate changes in international business cycle affiliations using an iterative procedure for detecting system-wide structural breaks. We analyze GDP growth rates in two systems, one with the US, Euro-area, UK and Canada and the other for the Euro-area countries of France, Germany and Italy. We discover that international dynamic interactions change in both the mid-1980s and early 1990s, with such changes being particularly important for studying influences on the aggregate Euro-area. ...

  5. Transportation life cycle assessment (LCA) synthesis : life cycle assessment learning module series.

    Science.gov (United States)

    2015-03-12

    The Life Cycle Assessment Learning Module Series is a set of narrated, self-advancing slideshows on : various topics related to environmental life cycle assessment (LCA). This research project produced the first 27 of such modules, which : are freely...

  6. Efficient cycles for carbon capture CLC power plants based on thermally balanced redox reactors

    KAUST Repository

    Iloeje, Chukwunwike

    2015-10-01

    © 2015 Elsevier Ltd. The rotary reactor differs from most alternative chemical looping combustion (CLC) reactor designs because it maintains near-thermal equilibrium between the two stages of the redox process by thermally coupling channels undergoing oxidation and reduction. An earlier study showed that this thermal coupling between the oxidation and reduction reactors increases the efficiency by up to 2% points when implemented in a regenerative Brayton cycle. The present study extends this analysis to alternative CLC cycles with the objective of identifying optimal configurations and design tradeoffs. Results show that the increased efficiency from reactor thermal coupling applies only to cycles that are capable of exploiting the increased availability in the reduction reactor exhaust. Thus, in addition to the regenerative cycle, the combined CLC cycle and the combined-regenerative CLC cycle are suitable for integration with the rotary reactor. Parametric studies are used to compare the sensitivity of the different cycle efficiencies to parameters like pressure ratio, turbine inlet temperature, carrier-gas fraction and purge steam generation. One of the key conclusions from this analysis is that while the optimal efficiency for regenerative CLC cycle was the highest of the three (56% at 3. bars, 1200. °C), the combined-regenerative cycle offers a trade-off that combines a reasonably high efficiency (about 54% at 12. bars, 1200. °C) with much lower gas volumetric flow rate and consequently, smaller reactor size. Unlike the other two cycles, the optimal compressor pressure ratio for the regenerative cycle is weakly dependent on the design turbine inlet temperature. For the regenerative and combined regenerative cycles, steam production in the regenerator below 2× fuel flow rate improves exhaust recovery and consequently, the overall system efficiency. Also, given that the fuel side regenerator flow is unbalanced, it is more efficient to generate steam from the

  7. Real-world experience of women using extended-cycle vs monthly-cycle combined oral contraception in the United States: the National Health and Wellness Survey.

    Science.gov (United States)

    Nappi, Rossella E; Lete, Iñaki; Lee, Lulu K; Flores, Natalia M; Micheletti, Marie-Christine; Tang, Boxiong

    2018-01-18

    The real-world experience of women receiving extended-cycle combined oral contraception (COC) versus monthly-cycle COC has not been reported. Data were from the United States 2013 National Health and Wellness Survey. Eligible women (18-50 years old, premenopausal, without hysterectomy) currently using extended-cycle COC (3 months between periods) were compared with women using monthly-cycle COC. Treatment satisfaction (1 "extremely dissatisfied" to 7 "extremely satisfied"), adherence (8-item Morisky Medication Adherence Scale © ), menstrual cycle-related symptoms, health-related quality of life (HRQOL) and health state utilities (Medical Outcomes Short Form Survey-36v2®), depression (9-item Patient Health Questionnaire), sleep difficulties, Work Productivity and Activity Impairment-General Health, and healthcare resource use were assessed using one-way analyses of variance, chi-square tests, and generalized linear models (adjusted for covariates). Participants included 260 (6.7%) women using extended-cycle and 3616 (93.3%) using monthly-cycle COC. Women using extended-cycle COC reported significantly higher treatment satisfaction (P = 0.001) and adherence (P = 0.04) and reduced heavy menstrual bleeding (P = 0.029). A non-significant tendency toward reduced menstrual pain (39.5% versus 47.3%) and menstrual cycle-related symptoms (40.0% versus 48.7%) was found in women using extended-cycle versus monthly-cycle COC. Significantly more women using extended-cycle COC reported health-related diagnoses, indicating preferential prescription for extended-cycle COC among women reporting more health problems. Consistent with this poorer health, more women using extended-cycle COC reported fatigue, headache, and activity impairment (P values cycle COC as a valuable treatment option with high satisfaction, high adherence, and reduced heavy menstrual bleeding.

  8. DETERMINANTS OF ENTERPRISES LIFE CYCLE IN MODERN CONDITIONS OF DEVELOPMENT

    Directory of Open Access Journals (Sweden)

    Alla Polianska

    2016-03-01

    Full Text Available In the article the theoretical basis of organization life cycle research as well as the particularly of the organization life cycle concept implementation for solving of modern targets of enterprises and organizations development are highlighted. The determinants of one life cycle stage transformation to the other at the enterprises, that allows to better understand the conditions of its functioning and to identify factors that affect the viability of the company and its duration, are considered. Management technologies at different stages of organizations life cycle are proposed. Keywords: enterprise, development, organizations life cycle, determinants, Oil and Gas company JEL: M 20

  9. Economic comparison of fusion fuel cycles

    International Nuclear Information System (INIS)

    Brereton, S.J.; Kazimi, M.S.

    1987-01-01

    The economics of the DT, DD, and DHe fusion fuel cycles are evaluated by comparison on a consistent basis. The designs for the comparison employ HT-9 structure and helium coolant; liquid lithium is used as the tritium breeding material for the DT fuel cycle. The reactors are pulsed, superconducting tokamaks, producing 1200 MW of electric power. The DT and DD designs scan a range of values of plasma beta, assuming first stability scaling laws. The results indicate that on a purely economic basis, the DT fuel cycle is superior to both of the advanced fuel cycles. Geometric factors, materials limitations, and plasma beta were seen to have an impact on the Cost of Electricity (COE). The economics for the DD fuel cycle are more strongly affected by these parameters than is the DT fuel cycle. Fuel costs are a major factor in determining the COE for the DHe fuel cycle. Based on costs directly attributable to the fuel cycle, the DT fuel cycle appears most attractive. Technological advances, improved understanding of physics, or strides in advanced energy conversion schemes may result in altering the economic ranking of the fuel cycles indicated here. 7 refs., 6 figs., 2 tabs

  10. VVER-440 fuel cycles possibilities using modified FA design

    International Nuclear Information System (INIS)

    Mikolas, P.; Svarny, J.; Razym, V.; Dostal, M.; Jenik, J.; Krupar, P.

    2009-01-01

    A nearly equilibrium five-year cycle has been achieved at Dukovany NPP over the last years. This means that working fuel assemblies (WFA) with an average enrichment of 4.25 w% (control assemblies (CA) with an average enrichment of 3.82 w%) are normally loaded and reloaded for five years. Operation at uprated thermal power (105% of the original one, increase from 1375 MW t to 1444 MW t ) is being prepared by use of WFA with an average enrichment of 4.38 w% (CA with an average enrichment of 4.25 w%). With the aim of fuel cycle economy improvement, the fuel residence time in the core has to be prolonged up to six years with one cycle duration time up to 18 months and preserving loadings with very low leakage. In order to achieve this goal, at least neutron-physical characteristics of FA must be improved and such changes should be evaluated from other viewpoints. Some particular changes have already been analyzed earlier. Designs of new fuel assemblies with higher (and in the central part of a FA the highest possible, i.e. 4.95 w%) enrichment with preserving low pin power non-uniformity are described in the presented paper. An FA with an average enrichment of 4.66 w% (lower than originally evaluated) containing six fuel pins with 3.35 w% Gd 2 O 3 content was selected in the end. Fuel pins have bigger pellet diameter, bigger pin pitch and thinner FA shroud. A newly designed FA was evaluated from the viewpoint of physics (pin power non-uniformity, criticality of fuel at transport and storage and determination of basic quantities for spent fuel storage purposes by ORIGEN code), thermo-hydraulics (comparison of subchannel output temperatures and the departure from nucleate boiling ratio - DNBR) and mechanical properties. The purpose of this study was to simulate an FA subject to the loads during its six- year lifetime whereas normal working conditions were taken into account. There are presented two models with different shroud thickness undergoing these analyses. Both

  11. Cycle layout studies of S-CO2 cycle for the next generation nuclear system application

    International Nuclear Information System (INIS)

    Ahn, Yoonhan; Bae, Seong Jun; Kim, Minseok; Cho, Seong Kuk; Baik, Seungjoon; Lee, Jeong Ik; Cha, Jae Eun

    2014-01-01

    According to the second law of thermodynamics, the next generation nuclear reactor system efficiency can potentially be increased with higher operating temperature. Fig.1 shows several power conversion system efficiencies and heat sources with respect to the system top operating temperature. As shown in Fig.1, the steam Rankine and gas Brayton cycles have been considered as the major power conversion systems more than several decades. In the next generation reactor operating temperature region (450 - 900 .deg. C), the steam Rankine and gas Brayton cycles have limits due to material problems and low efficiency, respectively. Among the future power conversion systems, S-CO 2 cycle is receiving interests due to several benefits including high efficiency under the mild turbine inlet temperature range (450-650 .deg. C), compact turbomachinery and simple layout compared to the steam Rankine cycle. S-CO 2 cycle can show relatively high efficiency under the mild turbine inlet temperature range (450-600 .deg. C) compared to other power conversion systems. The recompression cycle shows the best efficiency among other layouts and it is suitable for the application to advanced nuclear reactor systems. As S-CO 2 cycle performance can vary depending on the layout configuration, further studies on the layouts are required to design a better performing cycle

  12. An experimental and theoretical study on an injection-assisted air-conditioner using R32 in the refrigeration cycle

    International Nuclear Information System (INIS)

    Qv, Dehu; Dong, Bingbing; Cao, Lin; Ni, Long; Wang, Jijin; Shang, Runxin; Yao, Yang

    2017-01-01

    Highlights: • An advanced injection-assisted air-conditioner (IAC) using R32 was proposed. • In the whole day-night cycle, cooling capacity and energy efficiency ratio of the IAC were enhanced dramatically. • The injection duration of 8 s maximized the IAC cooling potential. • Two-phase injection attained the highest exergetic efficiency approximating 50% or more. • The economic and environmental benefits of the IAC were demonstrated. - Abstract: An air-conditioner (AC) that uses refrigerant R32 assisted with one-phase vapor injection shows high energy efficiency and low discharge temperature in the heat-pump cycle, but the performance is not satisfactory in the refrigeration cycle. In this study, an improved injection cycle consisting of one-phase vapor injection mode and two-phase injection mode is proposed and integrated into an AC using R32, which is now referred to as an advanced injection-assisted air-conditioner (IAC). Through an experimental and theoretical study, an optimal injection duration of 8 s is attained for maximizing the refrigeration potential of the IAC. Furthermore, in an entire day–night cycle, both the cooling capacity and energy efficiency ratio (EER) of the IAC within the two-phase injection cycle are enhanced by 25% and 32%, respectively, compared with those of a noninjection-assisted AC. Moreover, two-phase injection offers the highest exergetic efficiency, approximately 50% or more in the refrigeration cycle, exhibiting remarkable thermodynamic performance of the IAC. In addition, compared to the conventional AC using R410A, the IAC using R32 within a two-phase injection cycle demonstrates reasonable payback performance and substantial reduction in carbon dioxide and sulfur dioxide emissions in the refrigeration cycle.

  13. Integrated fuel-cycle models for fast breeder reactors

    International Nuclear Information System (INIS)

    Ott, K.O.; Maudlin, P.J.

    1981-01-01

    Breeder-reactor fuel-cycle analysis can be divided into four different areas or categories. The first category concerns questions about the spatial variation of the fuel composition for single loading intervals. Questions of the variations in the fuel composition over several cycles represent a second category. Third, there is a need for a determination of the breeding capability of the reactor. The fourth category concerns the investigation of breeding and long-term fuel logistics. Two fuel-cycle models used to answer questions in the third and fourth area are presented. The space- and time-dependent actinide balance, coupled with criticality and fuel-management constraints, is the basis for both the Discontinuous Integrated Fuel-Cycle Model and the Continuous Integrated Fuel-Cycle Model. The results of the continuous model are compared with results obtained from detailed two-dimensional space and multigroup depletion calculations. The continuous model yields nearly the same results as the detailed calculation, and this is with a comparatively insignificant fraction of the computational effort needed for the detailed calculation. Thus, the integrated model presented is an accurate tool for answering questions concerning reactor breeding capability and long-term fuel logistics. (author)

  14. The incidence of urea cycle disorders

    OpenAIRE

    Summar, Marshall L.; Koelker, Stefan; Freedenberg, Debra; Le Mons, Cynthia; Haberle, Johannes; Lee, Hye-Seung; Kirmse, Brian

    2013-01-01

    A key question for urea cycle disorders is their incidence. In the United States two UCDs argininosuccinic synthetase and lyase deficiency are currently detected by newborn screening. We used newborn screening data on over 6. million births and data from the large US and European longitudinal registries to determine how common these conditions are. The incidence for the United States is predicted to be 1 urea cycle disorder patient for every 35000 births presenting about 113 new patients per ...

  15. Gas fired combined cycle plant in Singapore: energy use, GWP and cost-a life cycle approach

    International Nuclear Information System (INIS)

    Kannan, R.; Leong, K.C.; Osman, Ramli; Ho, H.K.; Tso, C.P.

    2005-01-01

    A life cycle assessment was performed to quantify the non-renewable (fossil) energy use and global warming potential (GWP) in electricity generation from a typical gas fired combined cycle power plant in Singapore. The cost of electricity generation was estimated using a life cycle cost analysis (LCCA) tool. The life cycle assessment (LCA) of a 367.5 MW gas fired combined cycle power plant operating in Singapore revealed that hidden processes consume about 8% additional energy in addition to the fuel embedded energy, and the hidden GWP is about 18%. The natural gas consumed during the operational phase accounted for 82% of the life cycle cost of electricity generation. An empirical relation between plant efficiency and life cycle energy use and GWP in addition to a scenario for electricity cost with varying gas prices and plant efficiency have been established

  16. In anticipation of cycle 24

    Science.gov (United States)

    Kunches, Joseph; van der Linden, Ronald; Lundstedt, Henrik

    Anxious eyes are watching for the beginnings of new solar cycle 24. The watchers are many; scientists, engineers, academics, forecasters, end users. Their needs however vary, from the attraction of a better understanding of our nearest star, to how its increase in luminosity will affect particular aspects such as satellite orbits or the strength of the episodic storms that are most likely to occur during the height of the cycle. The first sign, however fleeting, occurred in January, 2008, when an ephemeral new cycle spot was numbered by NOAA as 10981. It was gone quickly but did mark the possible beginning of the new cycle. There has been great debate among solar physicists on how strong cycle 24 will be; and when it will start, reach maximum, and decline. This talk will give the status of the efforts to predict cycle 24, and the most recent projections.

  17. The economics of thorium fuel cycles

    International Nuclear Information System (INIS)

    James, R.A.

    1978-01-01

    The individual cost components and the total fuel cycle costs for natural uranium and thorium fuel cycles are discussed. The thorium cycles are initiated by using either enriched uranium or plutonium. Subsequent thorium cycles utilize recycled uranium-233 and, where necessary, either uranium-235 or plutonium as topping. A calculation is performed to establish the economic conditions under which thorium cycles are economically attractive. (auth)

  18. LIFE CYCLE DESIGN OF AMORPHOUS SILICON PHOTOVOLTAIC MODULES

    Science.gov (United States)

    The life cycle design framework was applied to photovoltaic module design. The primary objective of this project was to develop and evaluate design metrics for assessing and guiding the Improvement of PV product systems. Two metrics were used to assess life cycle energy perform...

  19. Dual-objective optimization of organic Rankine cycle (ORC) systems using genetic algorithm: a comparison between basic and recuperative cycles

    Science.gov (United States)

    Hayat, Nasir; Ameen, Muhammad Tahir; Tariq, Muhammad Kashif; Shah, Syed Nadeem Abbas; Naveed, Ahmad

    2017-08-01

    Exploitation of low potential waste thermal energy for useful net power output can be done by manipulating organic Rankine cycle systems. In the current article dual-objectives (η_{th} and SIC) optimization of ORC systems [basic organic Rankine cycle (BORC) and recuperative organic Rankine cycle (RORC)] has been done using non-dominated sorting genetic algorithm (II). Seven organic compounds (R-123, R-1234ze, R-152a, R-21, R-236ea, R-245ca and R-601) have been employed in basic cycle and four dry compounds (R-123, R-236ea, R-245ca and R-601) have been employed in recuperative cycle to investigate the behaviour of two systems and compare their performance. Sensitivity analyses show that recuperation boosts the thermodynamic behaviour of systems but it also raises specific investment cost significantly. R-21, R-245ca and R-601 show attractive performance in BORC whereas R-601 and R-236ea in RORC. RORC, due to higher total investment cost and operation & maintenance costs, has longer payback periods as compared to BORC.

  20. The nuclear fuel cycle versus the carbon cycle

    International Nuclear Information System (INIS)

    Ewing, R.C.

    2005-01-01

    Nuclear power provides approximately 17% of the world's electricity, which is equivalent to a reduction in carbon emissions of ∼0.5 gigatonnes (Gt) of C/yr. This is a modest reduction as compared with global emissions of carbon, ∼7 Gt C/yr. Most analyses suggest that in order to have a significant and timely impact on carbon emissions, carbon-free sources, such as nuclear power, would have to expand total production of energy by factors of three to ten by 2050. A three-fold increase in nuclear power capacity would result in a projected reduction in carbon emissions of 1 to 2 Gt C/yr, depending on the type of carbon-based energy source that is displaced. This three-fold increase utilizing present nuclear technologies would result in 25,000 metric tonnes (t) of spent nuclear fuel (SNF) per year, containing over 200 t of plutonium. This is compared to a present global inventory of approximately 280,000 t of SNF and >1,700 t of Pu. A nuclear weapon can be fashioned from as little as 5 kg of 239 Pu. However, there is considerable technological flexibility in the nuclear fuel cycle. There are three types of nuclear fuel cycles that might be utilized for the increased production of energy: open, closed, or a symbiotic combination of different types of reactor (such as, thermal and fast neutron reactors). The neutron energy spectrum has a significant effect on the fission product yield, and the consumption of long-lived actinides, by fission, is best achieved by fast neutrons. Within each cycle, the volume and composition of the high-level nuclear waste and fissile material depend on the type of nuclear fuel, the amount of burn-up, the extent of radionuclide separation during reprocessing, and the types of materials used to immobilize different radionuclides. As an example, a 232 Th-based fuel cycle can be used to breed fissile 233 U with minimum production of Pu. In this paper, I will contrast the production of excess carbon in the form of CO 2 from fossil fuels with

  1. INTERACTION BETWEEN MODELS OF THE LIFE CYCLE OF INDUSTRIAL ENTERPRISE AND CYCLE OF ITS REORGANIZATION

    Directory of Open Access Journals (Sweden)

    Chulkov Vitaliy Olegovich

    2012-10-01

    Full Text Available The objective of this scientific research is to develop a theoretical model of organizational and technology-related processes of reorganization of industrial enterprises, as well as their interaction. Multipoint logic notions of growth and interaction phases are used as research methods. The author describes the basic stages of reorganization, the life cycle of industrial enterprises and the cycle of their transformation. The processes are presented as an infographical image that represents a concentric model of interaction. This concentric model represents interaction between two or more phases. The process is entitled infografical modeling on the polyfunctional level. The concentric model moves both clockwise and anti-clockwise. Basic organizational and technological processes of reorganization of industrial enterprises that include decision making in terms of expediency of reorganization, design, construction, and performance of industrial enterprises at full capacity, and further operation of the industrial enterprise are described in the paper. Attainment of this objective, namely, reorganization of an industrial enterprise, involves a huge amount of resources, including labour resources that need interaction with all parties of reorganization; therefore, the concentric model of interaction describing the basic cycle of reorganization, the life cycle of an industrial enterprise and the cycle of its conversion is a trustworthy representation of this process. The proposed concentric model of interaction should be used in the design of organizational and technology-related processes for integrated consideration of reorganization of enterprises required to understand and improve the efficiency of reorganizations and to control the reorganization of industrial facilities.

  2. Two-rate periodic protocol with dynamics driven through many cycles

    Science.gov (United States)

    Kar, Satyaki

    2017-02-01

    We study the long time dynamics in closed quantum systems periodically driven via time dependent parameters with two frequencies ω1 and ω2=r ω1 . Tuning of the ratio r there can unleash plenty of dynamical phenomena to occur. Our study includes integrable models like Ising and X Y models in d =1 and the Kitaev model in d =1 and 2 and can also be extended to Dirac fermions in graphene. We witness the wave-function overlap or dynamic freezing that occurs within some small/ intermediate frequency regimes in the (ω1,r ) plane (with r ≠0 ) when the ground state is evolved through a single cycle of driving. However, evolved states soon become steady with long driving, and the freezing scenario gets rarer. We extend the formalism of adiabatic-impulse approximation for many cycle driving within our two-rate protocol and show the near-exact comparisons at small frequencies. An extension of the rotating wave approximation is also developed to gather an analytical framework of the dynamics at high frequencies. Finally we compute the entanglement entropy in the stroboscopically evolved states within the gapped phases of the system and observe how it gets tuned with the ratio r in our protocol. The minimally entangled states are found to fall within the regime of dynamical freezing. In general, the results indicate that the entanglement entropy in our driven short-ranged integrable systems follow a genuine nonarea law of scaling and show a convergence (with a r dependent pace) towards volume scaling behavior as the driving is continued for a long time.

  3. Measuring Business Cycle Time.

    OpenAIRE

    Stock, James H

    1987-01-01

    The business cycle analysis of Arthur F. Burns and Wesley C. Mitchell and the National Bureau of Economic Research presumed that aggregate economic variables evolve on a time scale defined by business cycle turning points rather than by months or quarters. Do macroeconomic variables appear to evolve on an economic rather than a calendar time scale? Evidence presented here suggests that they do. However, the estimated economic time scales are only weakly related to business cycle time scales, ...

  4. US activities on fuel cycle transition scenarios

    International Nuclear Information System (INIS)

    McCarthy, Kathryn A.

    2010-01-01

    Countries with active nuclear programmes typically have as a goal transition to a closed fuel cycle. A closed fuel cycle enables long-term sustainability, provides waste management benefits, and as a system, can reduce overall proliferation risk. This transition will take many decades, thus the study of the actual transition is an important topic. The United States systems analysis activities as part of the Advanced Fuel Cycle Initiative (AFCI) provide the integrating analyses for the fuel cycle programme, and recent activities are focusing on transition options, and specifically, the dynamics of the transition. The United States is still studying both one-tier (recycling in fast reactors only) and two-tier (recycling in both thermal and fast reactors) systems, and the systems analysis activities provide insight into the trade-offs associated with the systems, and variations of each. Most recently, a series of sensitivity studies have been completed which provide insight into the behaviour of a transition system. These studies evaluate the impact of changing various parameters in the fuel cycle system, and provide insight into how the system will change as parameters change. Because these deployment analyses look at the development of nuclear energy systems over a long period of time, it is very unlikely that we will accurately predict the system's characteristics over time (for example, growth in electricity demand, how quickly nuclear reactors will be deployed, how many fast rectors versus thermal reactors, the conversion ratio of the fast reactors, etc.). How the system will develop will depend on a variety of factors, ranging from political to technical, rational to irrational. Because we cannot accurately predict the future, we need to understand how things could change, and what impact those changes have. Analyses of future fuel cycle systems require a number of assumptions. These include growth rates for nuclear energy, general architecture of fuel cycle

  5. Power generation from a 7700C heat source by means of a main steam cycle, a topping closed gas cycle and a ammonia bottoming cycle

    International Nuclear Information System (INIS)

    Tilliette, Z.P.

    1981-03-01

    For power generation, steam cycles make an efficient use of medium temperature heat sources. They can be adapted to dry cooling, higher power ratings and output increase in winter by addition of an ammonia bottoming cycle. Active development is carried out in this field by 'Electricite de France'. As far as heat sources at higher temperatures are concerned, particularly related to coal-fired or nuclear power plants, a more efficient way of converting energy is at first to expand a hot working fluid through a gas turbine. It is shown in this paper that a satisfactory result, for heat sources of about 770 0 C, is obtained with a topping closed gas cycle of moderate power rating, rejecting its waste heat into the main steam cycle. Attention has to be paid to this gas cycle waste heat recovery and to the coupling of the gas and steam cycles. This concept drastically reduces the importance of new technology components. The use and the significance of an ammonia bottoming cycle in this case are investigated

  6. Auditing hierarchical cycles to locate other inconsistencies in the UMLS.

    Science.gov (United States)

    Halper, Michael; Morrey, C Paul; Chen, Yan; Elhanan, Gai; Hripcsak, George; Perl, Yehoshua

    2011-01-01

    A cycle in the parent relationship hierarchy of the UMLS is a configuration that effectively makes some concept(s) an ancestor of itself. Such a structural inconsistency can easily be found automatically. A previous strategy for disconnecting cycles is to break them with the deletion of one or more parent relationships-irrespective of the correctness of the deleted relationships. A methodology is introduced for auditing of cycles that seeks to discover and delete erroneous relationships only. Cycles involving three concepts are the primary consideration. Hypotheses about the high probability of locating an erroneous parent relationship in a cycle are proposed and confirmed with statistical confidence and lend credence to the auditing approach. A cycle may serve as an indicator of other non-structural inconsistencies that are otherwise difficult to detect automatically. An extensive auditing example shows how a cycle can indicate further inconsistencies.

  7. Entrepreneurship and the Business Cycle

    NARCIS (Netherlands)

    Ph.D. Koellinger (Philipp); A.R. Thurik (Roy)

    2011-01-01

    textabstractWe find new empirical regularities in the business cycle in a cross-country panel of 22 OECD countries for the period 1972-2007; entrepreneurship Granger-causes the cycles of the world economy. Furthermore, the entrepreneurial cycle is positively affected by the national unemployment

  8. Lightweight two-stroke cycle aircraft diesel engine technology enablement program, volume 1

    Science.gov (United States)

    Freen, P. D.; Berenyi, S. G.; Brouwers, A. P.; Moynihan, M. E.

    1985-01-01

    An experimental Single Cylinder Test Engine Program is conducted to confirm the analytically projected performance of a two-stroke cycle diesel engine for aircraft applications. The test engine delivered 78kW indicated power from 1007cc displacement, operating at 3500 RPM on Schnuerle loop scavenged two-stroke cycle. Testing confirms the ability of a proposed 4-cylinder version of such an engine to reach the target power at altitude, in a highly turbocharged configuration. The experimental program defines all necessary parameters to permit design of a multicylinder engine for eventual flight applications; including injection system requirement, turbocharging, heat rejection, breathing, scavenging, and structural requirements. The multicylinder engine concept is configured to operate with an augmented turbocharger, but with no primary scavenge blower. The test program is oriented to provide a balanced turbocharger compressor to turbine power balance without an auxiliary scavenging system. Engine cylinder heat rejection to the ambient air has been significantly reduced and the minimum overall turbocharger efficiency required is within the range of commercially available turbochargers. Analytical studies and finite element modeling is made of insulated configurations of the engines - including both ceramic and metallic versions. A second generation test engine is designed based on current test results.

  9. Associations of cycling with urban sprawl and the gasoline price.

    Science.gov (United States)

    Rashad, Inas

    2009-01-01

    Determine the relationships between cycling and urban sprawl and between cycling and the gasoline price. Cross-sectional multivariate regression analyses using pooled data from two individual-level national surveys to analyze the effects of variations in levels of urban sprawl and the gasoline price on cycling as a form of physical activity. Metropolitan areas representative of the U.S. population, 1990 to 2001. Behavioral Risk Factor Surveillance System: 146,730 individuals at least 18-years-old in the United States; Nationwide Personal Transportation Survey: 73,903 individuals at least 18-years-old in the United States. Self-reported information on bicycling served as the dependent variable. Urban sprawl and the gasoline price served as key independent variables. Living in a metropolitan area with a lower degree of urban sprawl increased the probability of cycling in the past month by 3.4 to 4.4 percentage points and 1.6 to 2.1 percentage points from the means for men and women, respectively. Increasing the gasoline price by one dollar increased the probability of cycling by 4.3 to 4.7 percentage points and 2.9 to 3.5 percentage points for men and women, respectively. Results indicate that the prevalence of cycling is higher in less sprawling areas and areas with higher gasoline prices. More research is needed to refine results on how individuals respond to incentives and the roles that monetary and time costs play in improving public health.

  10. The Contemporary Carbon Cycle

    Science.gov (United States)

    Houghton, R. A.

    2003-12-01

    The global carbon cycle refers to the exchanges of carbon within and between four major reservoirs: the atmosphere, the oceans, land, and fossil fuels. Carbon may be transferred from one reservoir to another in seconds (e.g., the fixation of atmospheric CO2 into sugar through photosynthesis) or over millennia (e.g., the accumulation of fossil carbon (coal, oil, gas) through deposition and diagenesis of organic matter). This chapter emphasizes the exchanges that are important over years to decades and includes those occurring over the scale of months to a few centuries. The focus will be on the years 1980-2000 but our considerations will broadly include the years ˜1850-2100. Chapter 8.09, deals with longer-term processes that involve rates of carbon exchange that are small on an annual timescale (weathering, vulcanism, sedimentation, and diagenesis).The carbon cycle is important for at least three reasons. First, carbon forms the structure of all life on the planet, making up ˜50% of the dry weight of living things. Second, the cycling of carbon approximates the flows of energy around the Earth, the metabolism of natural, human, and industrial systems. Plants transform radiant energy into chemical energy in the form of sugars, starches, and other forms of organic matter; this energy, whether in living organisms or dead organic matter, supports food chains in natural ecosystems as well as human ecosystems, not the least of which are industrial societies habituated (addicted?) to fossil forms of energy for heating, transportation, and generation of electricity. The increased use of fossil fuels has led to a third reason for interest in the carbon cycle. Carbon, in the form of carbon dioxide (CO2) and methane (CH4), forms two of the most important greenhouse gases. These gases contribute to a natural greenhouse effect that has kept the planet warm enough to evolve and support life (without the greenhouse effect the Earth's average temperature would be -33

  11. Historicising the Hydrosocial Cycle

    Directory of Open Access Journals (Sweden)

    Jeremy J. Schmidt

    2014-02-01

    Full Text Available This paper examines the historical claims made in support of the hydrosocial cycle. In particular, it considers how arguments advancing the hydrosocial cycle make historical claims regarding modernist conceptions of what water is (i.e. H2O and its fit with society. The paper gives special emphasis to the society/nature dualism and to the notion of agency as key sites of contest in arguments regarding the hydrosocial cycle. It finds that, while several versions of the hydrosocial cycle seek to advance a political ecology more sensitive to non-human actions, these same accounts often do not address the robust account of non-human agency in the historical record. Evidence is presented regarding water’s agency amongst late 19th and early 20th century architects of key water management norms in the United States. This evidence troubles accounts of the hydrosocial cycle that critique the US experience and suggests new directions for rethinking the role of historical and institutional norms in water policy.

  12. Comparison of two thorium fuel cycles for use in light water prebreeder/breeder reactor systems (AWBA Development Program)

    International Nuclear Information System (INIS)

    Merriman, F.C.; McCoy, D.F.; Boyd, W.A.; Dwyer, J.R.

    1983-05-01

    Light water prebreeder/breeder conceptual reactor systems have been developed which have the potential to significantly improve the fuel utilization of present generation light water reactors. The purpose of this study is to describe and compare two possible types of thorium fuel cycles for use in these light water prebreeder and breeder concepts. The two types of thorium fuel cycles basically differ in the fuel rod design used in the prebreeder cores and the uranium isotopic concentration of fuel supplied to the breeder cores

  13. Life cycle assessment (LCA)

    DEFF Research Database (Denmark)

    Thrane, Mikkel; Schmidt, Jannick Andresen

    2004-01-01

    The chapter introduces Life Cycle Assessment (LCA) and its application according to the ISO 1404043 standards.......The chapter introduces Life Cycle Assessment (LCA) and its application according to the ISO 1404043 standards....

  14. Cycling biomechanics: a literature review.

    Science.gov (United States)

    Wozniak Timmer, C A

    1991-01-01

    Submitted in partial fulfillment for a Master of Science degree at the University of Pittsburgh, School of Health Related Professions, Pittsburgh, PA 1.5213 This review of current literature on cycling biomechanics emphasizes lower extremity muscle actions and joint excursions, seat height, pedal position, pedaling rate, force application, and pedaling symmetry. Guidelines are discussed for optimal seat height, pedal position, and pedaling rate. Force application in the power and recovery phases of cycling and the relationship of force application to pedaling symmetry are discussed. The need for a biomechanical approach to cycling exists since a great deal of the literature is primarily physiologic in nature. The purpose of this review is to make cyclists and their advisors aware of the biomechanics of cycling and guidelines to follow. This approach is also important because cycling is a very common form of exercise prescribed by physical therapists for clinic or home programs. Biomechanical aspects of cycling should be considered by cyclists at any level of participation and by physical therapists in order for goal-oriented, efficient cycling to occur. J Orthop Sports Phys Ther 1991;14(3):106-113.

  15. Weekly Cycles in Daily Report Data: An Overlooked Issue.

    Science.gov (United States)

    Liu, Yu; West, Stephen G

    2016-10-01

    Daily diaries and other everyday experience methods are increasingly used to study relationships between two time-varying variables X and Y. Although daily data potentially often have weekly cyclical patterns (e.g., stress may be higher on weekdays and lower on weekends), the majority of daily diary studies have ignored this possibility. In this study, we investigated the effect of ignoring existing weekly cycles. We reanalyzed an empirical dataset (stress and alcohol consumption) and performed Monte Carlo simulations to investigate the impact of omitting weekly cycles. In the empirical dataset, ignoring cycles led to the inference of a significant within-person X-Y relation whereas modeling cycles suggested that this relationship did not exist. Simulation results indicated that ignoring cycles that existed in both X and Y led to bias in the estimated within-person X-Y relationship. The amount and direction of bias depended on the magnitude of the cycles, magnitude of the true within-person X-Y relation, and synchronization of the cycles. We encourage researchers conducting daily diary studies to address potential weekly cycles in their data. We provide guidelines for detecting and modeling cycles to remove their influence and discuss challenges of causal inference in daily experience studies. © 2015 Wiley Periodicals, Inc.

  16. An exergoeconomic assessment of waste heat recovery from a Gas Turbine-Modular Helium Reactor using two transcritical CO_2 cycles

    International Nuclear Information System (INIS)

    Wang, Xurong; Dai, Yiping

    2016-01-01

    Highlights: • A Gas Turbine-Modular Helium Reactor is coupled with two transcritical CO_2 cycles. • Exergoeconomic analysis and optimization of the combined cycle was performed. • The energy efficiency of the cogeneration system was enhanced by 7.92% at 850 °C. • The overall exergoeconomic factor of the system could up to 55.2%. - Abstract: A comprehensive study is performed on an energy conversion system which combines a gas turbine-modular helium reactor (GT-MHR) and two transcritical CO_2 cycles (tCO_2). The aim of this study is to assess the energy, exergy and economic behavior of the proposed system, considering five indicators: the energy efficiency, the exergy efficiency, the total exergy destruction cost rate, the overall exergoeconomic factor and the total cost rate. A parametric study is also conducted to evaluate the influence of key decision variables on the GT-MHR/tCO_2 performance. Finally, the combined cycle is optimized to minimize the total cost rate. The results show that the energy efficiency of GT-MHR/tCO_2 cycle is 7.92% higher than that of the simple GT-MHR cycle at 850 °C. The largest exergy destruction rate takes place in the reactor, and after that in the helium turbine and the recuperator. The components in tCO_2 cycles have less exergy destruction. When the optimization is conducted based on the exergoeconomics, the overall exergoeconomic factor, the total cost rate and the total exergy destruction cost rate are 55.2%, 20,752 $/h and 9292 $/h, respectively.

  17. A model for hormonal control of the menstrual cycle: structural consistency but sensitivity with regard to data.

    Science.gov (United States)

    Selgrade, J F; Harris, L A; Pasteur, R D

    2009-10-21

    This study presents a 13-dimensional system of delayed differential equations which predicts serum concentrations of five hormones important for regulation of the menstrual cycle. Parameters for the system are fit to two different data sets for normally cycling women. For these best fit parameter sets, model simulations agree well with the two different data sets but one model also has an abnormal stable periodic solution, which may represent polycystic ovarian syndrome. This abnormal cycle occurs for the model in which the normal cycle has estradiol levels at the high end of the normal range. Differences in model behavior are explained by studying hysteresis curves in bifurcation diagrams with respect to sensitive model parameters. For instance, one sensitive parameter is indicative of the estradiol concentration that promotes pituitary synthesis of a large amount of luteinizing hormone, which is required for ovulation. Also, it is observed that models with greater early follicular growth rates may have a greater risk of cycling abnormally.

  18. Optimizing the allocation of resources for genomic selection in one breeding cycle.

    Science.gov (United States)

    Riedelsheimer, Christian; Melchinger, Albrecht E

    2013-11-01

    We developed a universally applicable planning tool for optimizing the allocation of resources for one cycle of genomic selection in a biparental population. The framework combines selection theory with constraint numerical optimization and considers genotype  ×  environment interactions. Genomic selection (GS) is increasingly implemented in plant breeding programs to increase selection gain but little is known how to optimally allocate the resources under a given budget. We investigated this problem with model calculations by combining quantitative genetic selection theory with constraint numerical optimization. We assumed one selection cycle where both the training and prediction sets comprised double haploid (DH) lines from the same biparental population. Grain yield for testcrosses of maize DH lines was used as a model trait but all parameters can be adjusted in a freely available software implementation. An extension of the expected selection accuracy given by Daetwyler et al. (2008) was developed to correctly balance between the number of environments for phenotyping the training set and its population size in the presence of genotype × environment interactions. Under small budget, genotyping costs mainly determine whether GS is superior over phenotypic selection. With increasing budget, flexibility in resource allocation increases greatly but selection gain leveled off quickly requiring balancing the number of populations with the budget spent for each population. The use of an index combining phenotypic and GS predicted values in the training set was especially beneficial under limited resources and large genotype × environment interactions. Once a sufficiently high selection accuracy is achieved in the prediction set, further selection gain can be achieved most efficiently by massively expanding its size. Thus, with increasing budget, reducing the costs for producing a DH line becomes increasingly crucial for successfully exploiting the

  19. Two Chimeric Regulators of G-protein Signaling (RGS) Proteins Differentially Modulate Soybean Heterotrimeric G-protein Cycle*

    Science.gov (United States)

    Roy Choudhury, Swarup; Westfall, Corey S.; Laborde, John P.; Bisht, Naveen C.; Jez, Joseph M.; Pandey, Sona

    2012-01-01

    Heterotrimeric G-proteins and the regulator of G-protein signaling (RGS) proteins, which accelerate the inherent GTPase activity of Gα proteins, are common in animals and encoded by large gene families; however, in plants G-protein signaling is thought to be more limited in scope. For example, Arabidopsis thaliana contains one Gα, one Gβ, three Gγ, and one RGS protein. Recent examination of the Glycine max (soybean) genome reveals a larger set of G-protein-related genes and raises the possibility of more intricate G-protein networks than previously observed in plants. Stopped-flow analysis of GTP-binding and GDP/GTP exchange for the four soybean Gα proteins (GmGα1–4) reveals differences in their kinetic properties. The soybean genome encodes two chimeric RGS proteins with an N-terminal seven transmembrane domain and a C-terminal RGS box. Both GmRGS interact with each of the four GmGα and regulate their GTPase activity. The GTPase-accelerating activities of GmRGS1 and -2 differ for each GmGα, suggesting more than one possible rate of the G-protein cycle initiated by each of the Gα proteins. The differential effects of GmRGS1 and GmRGS2 on GmGα1–4 result from a single valine versus alanine difference. The emerging picture suggests complex regulation of the G-protein cycle in soybean and in other plants with expanded G-protein networks. PMID:22474294

  20. Thorium fuel cycle analysis

    Energy Technology Data Exchange (ETDEWEB)

    Yamaji, K [Central Research Inst. of Electric Power Industry, Tokyo (Japan)

    1980-07-01

    Systems analysis of the thorium cycle, a nuclear fuel cycle accomplished by using thorium, is reported in this paper. Following a brief review on the history of the thorium cycle development, analysis is made on the three functions of the thorium cycle; (1) auxiliary system of U-Pu cycle to save uranium consumption, (2) thermal breeder system to exert full capacity of the thorium resource, (3) symbiotic system to utilize special features of /sup 233/U and neutron sources. The effects of the thorium loading in LWR (Light Water Reactor), HWR (Heavy Water Reactor) and HTGR (High Temperature Gas-cooled Reactor) are considered for the function of auxiliary system of U-Pu cycle. Analysis is made to find how much uranium is saved by /sup 233/U recycling and how the decrease in Pu production influences the introduction of FBR (Fast Breeder Reactor). Study on thermal breeder system is carried out in the case of MSBR (Molten Salt Breeder Reactor). Under a certain amount of fissile material supply, the potential system expansion rate of MSBR, which is determined by fissile material balance, is superior to that of FBR because of the smaller specific fissile inventory of MSBR. For symbiotic system, three cases are treated; i) nuclear heat supply system using HTGR, ii) denatured fuel supply system for nonproliferation purpose, and iii) hybrid system utilizing neutron sources other than fission reactor.

  1. Modeling Business Cycle with Financial Shocks Basing on Kaldor-Kalecki Model

    Directory of Open Access Journals (Sweden)

    Zhenghui Li

    2017-04-01

    Full Text Available The effects of financial factors on real business cycle is rising to one of the most popular discussions in the field of macro business cycle theory. The objective of this paper is to discuss the features of business cycle under financial shocks by quantitative technology. More precisely, we introduce financial shocks into the classical Kaldor-Kalecki business cycle model and study dynamics of the model. The shocks include external shock and internal shock, both of which are expressed as noises. The dynamics of the model can help us understand the effects of financial shocks on business cycle and improve our knowledge about financial business cycle. In the case of external shock, if the intensity of shock is less than some threshold value, the economic system behaves randomly periodically. If the intensity of shock is beyond the threshold value, the economic system will converge to a normalcy. In the case of internal shock, if the intensity of shock is less than some threshold value, the economic system behaves periodically as the case without shock. If the intensity of shock exceeds the threshold value, the economic system either behaves periodically or converges to a normalcy. It is uncertain. The case with both two kinds of shocks is more complicated. We find conditions of the intensities of shocks under which the economic system behaves randomly periodically or disorderly, or converges to normalcy. Discussions about the effects of financial shocks on the business cycle are presented.

  2. Development of FR fuel cycle in japan (1) development scope of fuel cycle technology

    International Nuclear Information System (INIS)

    Nakamura, H.; Funasaka, H.; Namekawa, T.

    2008-01-01

    A fast reactor (FR) cycle has a potential to realize a sustainable energy supply system that is harmonized with environment by fully recycling both uranium (U) and transuranium (TRU) elements. In Japan, a Feasibility Study on Commercialized FR Cycle Systems (FS) was launched in July 1999, and through two different study phases, a final report was presented in 2006. As a result of FS, a combined system of sodium-cooled FR with mixed-oxide (MOX) fuel, advanced aqueous reprocessing and simplified pelletizing fuel fabrication was considered to be most promising for commercialization. The advanced aqueous reprocessing system, which is called the New Extraction system for TRU recovery (NEXT), consists of a U crystallization process for the bulk of U recovery, a simplified solvent extraction process for residual U, plutonium (Pu) and neptunium (Np) without Pu partitioning and purification, and a process for recovering americium (Am) and curium (Cm) from the raffinate. The ratio of Pu/U concentration in the mother solution after crystallization is adequate for MOX fuel fabrication, and thus complicated powder mixing processes for adjusting Pu content in MOX fuel can be eliminated in the subsequent simplified fuel fabrication system. In this system, lubricant-mixing process can also be eliminated by adopting the advanced technology in which lubricant is coated on the inner surface of a die before fuel powder supply. Such a simplification could help us overcoming the difficulty to treat MA bearing fuel powders in a hot cell. Ministry of Education, Culture, Sports, Science and Technology (MEXT) reviewed these results of FS in 2006 and identified the most promising FR cycle concept proposed in the FS phase II study as a mainline choice for commercialization. According to such a governmental assessment, R and D activities of FR cycle systems were decided to be concentrated mainly to the innovative technology development for the mainline concept. The stage of R and D project was

  3. The onset of the solar active cycle 22

    International Nuclear Information System (INIS)

    Ahluwalia, H.S.

    1989-01-01

    There is a great deal of interest in being able to predict the main characteristics of a solar activity cycle (SAC). One would like to know, for instance, how large the amplitude (R sub m) of a cycle is likely to be, i.e., the annual mean of the sunspot numbers at the maximum of SAC. Also, how long a cycle is likely to last, i.e., its period. It would also be interesting to be able to predict the details, like how steep the ascending phase of a cycle is likely to be. Questions like these are of practical importance to NASA in planning the launch schedule for the low altitude, expensive spacecrafts like the Hubble Space Telescope, the Space Station, etc. Also, one has to choose a proper orbit, so that once launched the threat of an atmospheric drag on the spacecraft is properly taken into account. Cosmic ray data seem to indicate that solar activity cycle 22 will surpass SAC 21 in activity. The value of R sub m for SAC 22 may approach that of SAC 19. It would be interesting to see whether this prediction is borne out. Researchers are greatly encouraged to proceed with the development of a comprehensive prediction model which includes information provided by cosmic ray data

  4. The onset of the solar active cycle 22

    Science.gov (United States)

    Ahluwalia, H. S.

    1989-01-01

    There is a great deal of interest in being able to predict the main characteristics of a solar activity cycle (SAC). One would like to know, for instance, how large the amplitude (R sub m) of a cycle is likely to be, i.e., the annual mean of the sunspot numbers at the maximum of SAC. Also, how long a cycle is likely to last, i.e., its period. It would also be interesting to be able to predict the details, like how steep the ascending phase of a cycle is likely to be. Questions like these are of practical importance to NASA in planning the launch schedule for the low altitude, expensive spacecrafts like the Hubble Space Telescope, the Space Station, etc. Also, one has to choose a proper orbit, so that once launched the threat of an atmospheric drag on the spacecraft is properly taken into account. Cosmic ray data seem to indicate that solar activity cycle 22 will surpass SAC 21 in activity. The value of R sub m for SAC 22 may approach that of SAC 19. It would be interesting to see whether this prediction is borne out. Researchers are greatly encouraged to proceed with the development of a comprehensive prediction model which includes information provided by cosmic ray data.

  5. Ecology and Life Cycle Patterns of Echinococcus Species.

    Science.gov (United States)

    Romig, T; Deplazes, P; Jenkins, D; Giraudoux, P; Massolo, A; Craig, P S; Wassermann, M; Takahashi, K; de la Rue, M

    2017-01-01

    The genus Echinococcus is composed of eight generally recognized species and one genotypic cluster (Echinococcus canadensis cluster) that may in future be resolved into one to three species. For each species, we review existing information on transmission routes and life cycles in different geographical contexts and - where available - include basic biological information of parasites and hosts (e.g., susceptibility of host species). While some Echinococcus spp. are transmitted in life cycles that involve predominantly domestic animals (e.g., dog - livestock cycles), others are wildlife parasites that do or do not interact with domestic transmission. In many cases, life cycle patterns of the same parasite species differ according to geography. Simple life cycles contrast with transmission patterns that are highly complex, involving multihost systems that may include both domestic and wild mammals. Wildlife transmission may be primary or secondary, i.e., resulting from spillovers from domestic animals. For most of the species and regions, existing information does not yet permit a conclusive description of transmission systems. Such data, however, would be highly relevant, e.g., for anticipation of geographical changes of the presence and frequency of these parasites in a warming world, or for initiating evidence-based control strategies. Copyright © 2017 Elsevier Ltd. All rights reserved.

  6. [Clinical outcomes and economic analysis of two ovulation induction protocols in patients undergoing repeated IVF/ICSI cycles].

    Science.gov (United States)

    Chen, Xiao; Geng, Ling; Li, Hong

    2014-04-01

    To compare the clinical outcomes and cost-effectiveness of luteal phase down-regulation with gonadotrophin-releasing hormone (GnRH) agonist protocol and GnRH antagonist protocol in patients undergoing repeated in vitro fertilization and intracytoplasmic sperm injection (IVF-ICSI) cycles. A retrospective analysis of clinical outcomes and costs was conducted among 198 patients undergoing repeated IVF-ICSI cycles, including 109 receiving luteal phase down-regulation with GnRH agonist protocol (group A) and 89 receiving GnRH antagonist protocol (group B). The numbers of oocytes retrieved and good embryos, clinical pregnancy rate, abortion rate, the live birth rate, mean total cost, and the cost-effective ratio were compared between the two groups. In patients undergoing repeated IVF-ICSI cycles, the two protocols produced no significant differences in the number of good embryos, clinical pregnancy rate, abortion rate, or twin pregnancy rate. Compared with group B, group A had better clinical outcomes though this difference was not statistically significant. The number of retrieved oocytes was significantly greater and live birth rate significantly higher in group A than in group B (9.13=4.98 vs 7.11=4.74, and 20.2% vs 9.0%, respectively). Compared with group B, group A had higher mean total cost per cycle but lower costs for each oocyte retrieved (2729.11 vs 3038.60 RMB yuan), each good embryo (8867.19 vs 9644.85 RMB yuan), each clinical pregnancy (77598.06 vs 96139.85 RMB yuan). For patients undergoing repeated IVF/ICSI cycle, luteal phase down-regulation with GnRH agonist protocol produces good clinical outcomes with also good cost-effectiveness in spite an unsatisfactory ovarian reserve.

  7. MUICYCL and MUIFAP: models tracking minor uranium isotopes in the nuclear fuel cycle

    International Nuclear Information System (INIS)

    Blum, S.R.; McLaren, R.A.

    1979-10-01

    Two computer programs have been written to provide information on the buildup of minor uranium isotopes in the nuclear fuel cycle. The Minor Uranium Isotope Cycle Program, MUICYCL, tracks fuel through a multiyear campaign cycle of enrichment, reactor burnup, reprocessing, enrichment, etc. MUICYCL facilities include preproduction stockpiles, U 235 escalation, and calculation of losses. The Minor Uranium Isotope Flowsheet Analyzer Program, MUIFAP, analyzes one minor isotope in one year of an enrichment operation. The formulation of the enrichment cascade, reactors, and reprocessing facility is presented. Input and output descriptions and sample cases are presented. The programs themselves are documented by short descriptions of each routine, flowcharts, definitions of common blocks and variables, and internal documentation. The programs are written in FORTRAN for use in batch mode

  8. HTR-Based Power Plants’ Performance Analysis Applied on Conventional Combined Cycles

    Directory of Open Access Journals (Sweden)

    José Carbia Carril

    2015-01-01

    Full Text Available In high temperature reactors including gas cooled fast reactors and gas turbine modular helium reactors (GT-MHR specifically designed to operate as power plant heat sources, efficiency enhancement at effective cost under safe conditions can be achieved. Mentioned improvements concern the implementation of two cycle structures: (a, a stand alone Brayton operating with helium and a stand alone Rankine cycle (RC with regeneration, operating with carbon dioxide at ultrasupercritical pressure as working fluid (WF, where condensation is carried out at quasicritical conditions, and (b, a combined cycle (CC, in which the topping closed Brayton cycle (CBC operates with helium as WF, while the bottoming RC is operated with one of the following WFs: carbon dioxide, xenon, ethane, ammonia, or water. In both cases, an intermediate heat exchanger (IHE is proposed to provide thermal energy to the closed Brayton or to the Rankine cycles. The results of the case study show that the thermal efficiency, through the use of a CC, is slightly improved (from 45.79% for BC and from 50.17% for RC to 53.63 for the proposed CC with He-H2O operating under safety standards.

  9. On the maximum number of cycles in a planar graph

    DEFF Research Database (Denmark)

    Aldred, R.E.L.; Thomassen, Carsten

    2008-01-01

    Let G be a graph on p vertices with q edges and let r = q - p + 1. We show that G has at most 15/162(r) cycles. We also show that if G is planar, then G has at most 2(r-1) + o(2(r-1)) cycles. The planar result is best possible in the sense that any prism, that is, the Cartesian product of a cycle...... and a path with one edge, has more than 2(r-1) cycles....

  10. Optimal Life Cycle Portfolio Choice with Housing Market Cycles

    DEFF Research Database (Denmark)

    Fischer, Marcel; Stamos, Michael Z.

    2013-01-01

    income, and pre-existing housing wealth but also the state of the housing market significantly affect household decisions. Consistently with the data, the model predicts that in good states of housing market cycles (1) homeownership rates increase, (2) households buying homes invest a larger share......In recent decades U.S. households have experienced residential house prices moving persistently, that is, returns being positively serially correlated. We set up a realistically calibrated life cycle model with slow-moving time variation in expected housing returns, showing that not only age, labor...

  11. The environmental impact of organic Rankine cycle for waste heat recovery through life-cycle assessment

    International Nuclear Information System (INIS)

    Liu, Chao; He, Chao; Gao, Hong; Xie, Hui; Li, Yourong; Wu, Shuangying; Xu, Jinliang

    2013-01-01

    The LCA (life-cycle assessment) was applied to evaluate EI (the environmental impact) of ORCPW (organic Rankine cycle power-plant for waste-heat-recovery) in this paper. The model of LCA on the ORCPW was established. The life-cycle of ORCPW was divided into construction, operation and decommissioning phases. The inventory of environmental emissions was listed for the ORCPW with 7 different working fluids. The GWP (global warming potential), AP (acidification potential), EP (eutrophication potential), HTP (human toxicity potential), SWP (solid waste potential) and SAP (soot and dust potential) were investigated. Some EIs of ORCPW were compared with the EIs of other power generation modes. The results show that the construction phase of ORCPW contributes mostly to the GWP and EP. GWP is the most serious EI followed by HTP among all the environmental impacts. The average pay back times of greenhouse gas discharged from ORCPW is calculated on the basis of five other power generation modes. For 7 different working fluids, it is 3–5 years for CO 2 , about one year for CH 4 and 3–6 years for NO x . But CO cannot be paid back during the life-cycle of ORCPW according to the average pay back time. - Highlights: • LCA was proposed to evaluate the environmental performance of ORC. • The ORC life cycle environmental emissions inventory was established. • GWP is the most serious environmental impact, followed by HTP. • The ORC with R113 exhibits the lowest environment impact load, followed by Pentane. • The total GWP of ORC could be paid back in 5 years

  12. Tourist Demand Reactions: Symmetric or Asymmetric across the Business Cycle?

    Science.gov (United States)

    Bronner, Fred; de Hoog, Robert

    2017-09-01

    Economizing and spending priorities on different types of vacations are investigated during two periods: an economic downturn and returning prosperity. Two nation-wide samples of vacationers are used: one during a downturn, the other one at the start of the recovery period. Through comparing the results, conclusions can be drawn about symmetric or asymmetric tourist demand across the business cycle. The main summer holiday has an asymmetric profile: being fairly crisis-resistant during a recession and showing considerable growth during an expansion. This does not apply to short vacations and day trips, each having a symmetric profile: during a recession they experience substantial reductions and during expansion comparable growth. So when talking about tourist demand in general , one cannot say that it is symmetric or asymmetric across the business cycle: it depends on the type of vacation. Differences in tourist demand are best explained by the role of Quality-of-Life for vacationers.

  13. WWER-440 fuel cycles possibilities using improved fuel assemblies design

    International Nuclear Information System (INIS)

    Mikolas, P.; Svarny, J.

    2008-01-01

    Practically five years cycle has been achieved in the last years at NPP Dukovany. There are two principal means how it could be achieved. First, it is necessary to use fuel assemblies with higher fuel enrichment and second, to use fuel loading with very low leakage. Both these conditions are fulfilled at NPP Dukovany at this time. It is known, that the fuel cycle economy can be improved by increasing the fuel residence time in the core up to six years. There are at least two ways how this goal could be achieved. The simplest way is to increase enrichment in fuel. There exists a limit, which is 5.0 w % of 235 U. Taking into account some uncertainty, the calculation maximum is 4.95 w % of 235 U. The second way is to change fuel assembly design. There are several possibilities, which seem to be suitable from the neutron - physical point of view. The first one is higher mass content of uranium in a fuel assembly. The next possibility is to enlarge pin pitch. The last possibility is to 'omit' FA shroud. This is practically unrealistic; anyway, some other structural parts must be introduced. The basic neutron physical characteristics of these cycles for up-rated power are presented showing that the possibilities of fuel assemblies with this improved design in enlargement of fuel cycles are very promising. In the end, on the basis of neutron physical characteristics and necessary economical input parameters, a preliminary evaluation of economic contribution of proposals of advanced fuel assemblies on fuel cycle economy is presented (Authors)

  14. Using the Boston Matrix at Identification of the Corporate Life Cycle Stage

    Directory of Open Access Journals (Sweden)

    Zdeněk Konečný

    2015-01-01

    Full Text Available The main aim of this article is to develop a new model supporting the identification of the particular corporate life stage within the corporate life cycle. This model will be derived from the Boston matrix. The main reason for using this approach as the base for making new model of the corporate life cycle is the fact, that every quadrant of the Boston matrix can be assigned to one phase of the product life cycle and there is supposed, that the phase, in which are most products, determines the phase of the corporate life cycle. For application the Boston matrix by identification phases of the corporate life cycle is necessary to define low and high values of both its variables using some quantities from the model of corporate- and market life cycle by Reiners (2004. So the interval of low and high sales growth is determined by comparing sales of the company and sales of the market and furthermore, there is considered the rate of inflation to eliminate the impact of price changes. And for determination low and high market shares, there are compared the shares of sales and shares of total assets. After that, there will be possible to identify all the quadrants and thus all the individual phases unequivocally, which is the basic advantage compared to most existing models of the corporate life cycle. The following aim of this article is to compare the occurrence of individual phases, identified by this modified model, depending on the sector sensitivity to the economic cycle, measured by the coefficient of correlation between sales on the market and GDP. There are selected two sectors of the Czech economy, namely one cyclical and one neutral sector. Subsequently there is selected a sample of companies from both these sectors. The data are collected from financial statements of companies and from analytical materials by the Czech Ministry of Industry and Trade and by the Czech Statistical Office. On the basis of this research, there were recorded

  15. Fuel cycle optimization in PWR'S

    International Nuclear Information System (INIS)

    Castro Lobo, P.D. de; Amorim, E.S. do.

    1979-08-01

    Neutronics aspects of a reactor core throughout its cycle were investigated in a search for increasing in-core utilization of the residual fissile isotopes content in the cycle discharged disposal. The effects due to design modifications introduced at burnup levels near the end-of-cycle, in an equilibrium cycle condition, have indicated the possibility of a better in-core utilization of the residual fissile isotopes existing in the cycle discharged disposal. The potential benefits are significant to warranty an examination of the mechanical and thermal hydraulic involved. At convenient burnup levels, change in H 2 O/UO 2 volume ratio were introduced allowing an intense depletion of the residual fissile isotopes existing in assemblies with high exposures levels. (Author) [pt

  16. Lessons Learned From Dynamic Simulations of Advanced Fuel Cycles

    International Nuclear Information System (INIS)

    Piet, Steven J.; Dixon, Brent W.; Jacobson, Jacob J.; Matthern, Gretchen E.; Shropshire, David E.

    2009-01-01

    Years of performing dynamic simulations of advanced nuclear fuel cycle options provide insights into how they could work and how one might transition from the current once-through fuel cycle. This paper summarizes those insights from the context of the 2005 objectives and goals of the Advanced Fuel Cycle Initiative (AFCI). Our intent is not to compare options, assess options versus those objectives and goals, nor recommend changes to those objectives and goals. Rather, we organize what we have learned from dynamic simulations in the context of the AFCI objectives for waste management, proliferation resistance, uranium utilization, and economics. Thus, we do not merely describe 'lessons learned' from dynamic simulations but attempt to answer the 'so what' question by using this context. The analyses have been performed using the Verifiable Fuel Cycle Simulation of Nuclear Fuel Cycle Dynamics (VISION). We observe that the 2005 objectives and goals do not address many of the inherently dynamic discriminators among advanced fuel cycle options and transitions thereof

  17. Stirling cycle engine

    Science.gov (United States)

    Lundholm, Gunnar

    1983-01-01

    In a Stirling cycle engine having a plurality of working gas charges separated by pistons reciprocating in cylinders, the total gas content is minimized and the mean pressure equalization among the serial cylinders is improved by using two piston rings axially spaced at least as much as the piston stroke and by providing a duct in the cylinder wall opening in the space between the two piston rings and leading to a source of minimum or maximum working gas pressure.

  18. The biennial cycle of respiratory syncytial virus outbreaks in Croatia

    Directory of Open Access Journals (Sweden)

    Drazenovic Vladimir

    2008-01-01

    Full Text Available Abstract The paper analyses the epidemic pattern of respiratory syncytial virus (RSV outbreaks in children in Croatia. Over a period of 11 consecutive winter seasons (1994–2005 3,435 inpatients from Zagreb County aged from infancy to 10 years who were hospitalised with acute respiratory tract infections were tested for RSV-infection. RSV was identified in nasopharyngeal secretions of patients by virus isolation in cell culture and by detection of viral antigen with monoclonal antibodies. In the Zagreb area, RSV outbreaks were proven to vary in a two-year cycle, which was repeated every 23–25 months. This biennial cycle comprised one larger and one smaller season. Climate factors correlated significantly with the number of RSV cases identified only in the large seasons, which suggests that the biennial cycle is likely to continue regardless of meteorological conditions. Knowledge of this biennial pattern should be useful in predicting the onset of RSV outbreaks in Croatia, and would facilitate planning for the prevention and control of RSV infections in the region.

  19. Hydrogen production at <550 C using a low temperature thermochemical cycle

    International Nuclear Information System (INIS)

    Lewis, M.A.; Serban, M.; Basco, J.K.

    2004-01-01

    A Department of Energy goal is to identify new technologies for producing hydrogen cost effectively without greenhouse gas emissions. Thermochemical cycles are one of the potential options under investigation. Thermochemical cycles consist of a series of reactions in which water is thermally decomposed and all other chemicals are recycled. Only heat and water are consumed. However, most thermochemical cycles require process heat at temperatures of 850-900 deg C. Argonne National Laboratory is developing low temperature cycles designed for lower temperature heat, 500-550 deg C, which is more readily available. For this temperature region, copper-chlorine (Cu-Cl) cycles are the most promising cycle. Several Cu-Cl cycles have been examined in the laboratory and the most promising cycle has been identified. Proof-of-principle experiments are nearly complete. A preliminary assessment of cycle efficiency is promising. Details of the experiments and efficiency calculations are discussed. (author)

  20. Estimating Externalities of Natural Gas Fuel Cycles, Report 4

    Energy Technology Data Exchange (ETDEWEB)

    Barnthouse, L.W.; Cada, G.F.; Cheng, M.-D.; Easterly, C.E.; Kroodsma, R.L.; Lee, R.; Shriner, D.S.; Tolbert, V.R.; Turner, R.S.

    1998-01-01

    This report describes methods for estimating the external costs (and possibly benefits) to human health and the environment that result from natural gas fuel cycles. Although the concept of externalities is far from simple or precise, it generally refers to effects on individuals' well being, that result from a production or market activity in which the individuals do not participate, or are not fully compensated. In the past two years, the methodological approach that this report describes has quickly become a worldwide standard for estimating externalities of fuel cycles. The approach is generally applicable to any fuel cycle in which a resource, such as coal, hydro, or biomass, is used to generate electric power. This particular report focuses on the production activities, pollution, and impacts when natural gas is used to generate electric power. In the 1990s, natural gas technologies have become, in many countries, the least expensive to build and operate. The scope of this report is on how to estimate the value of externalities--where value is defined as individuals' willingness to pay for beneficial effects, or to avoid undesirable ones. This report is about the methodologies to estimate these externalities, not about how to internalize them through regulations or other public policies. Notwithstanding this limit in scope, consideration of externalities can not be done without considering regulatory, insurance, and other considerations because these institutional factors affect whether costs (and benefits) are in fact external, or whether they are already somehow internalized within the electric power market. Although this report considers such factors to some extent, much analysis yet remains to assess the extent to which estimated costs are indeed external. This report is one of a series of reports on estimating the externalities of fuel cycles. The other reports are on the coal, oil, biomass, hydro, and nuclear fuel cycles, and on general