WorldWideScience

Sample records for aec-nim

  1. Standard NIM instrumentation system

    International Nuclear Information System (INIS)

    1990-05-01

    NIM is a standard modular instrumentation system that is in wide use throughout the world. As the NIM system developed and accommodations were made to a dynamic instrumentation field and a rapidly advancing technology, additions, revisions and clarifications were made. These were incorporated into the standard in the form of addenda and errata. This standard is a revision of the NIM document, AEC Report TID-20893 (Rev. 4) dated July 1974. It includes all the addenda and errata items that were previously issued as well as numerous additional items to make the standard current with modern technology and manufacturing practice

  2. 76 FR 3648 - NIMS Training Plan

    Science.gov (United States)

    2011-01-20

    ...] NIMS Training Plan AGENCY: Federal Emergency Management Agency, DHS. ACTION: Notice of availability... comments on the NIMS Training Plan. This plan defines National Incident Management System (NIMS) national... sustaining NIMS training. In addition to delineating responsibilities and actions, the NIMS Training Plan...

  3. The AEC and developing countries

    International Nuclear Information System (INIS)

    Ouvrieu, J.B.

    1983-01-01

    A historical background shows how AEC's activities have changed and consequently, the development of the AEC's relations with developing countries. Some examples serve to illustrate the different types of AEC cooperation with developing countries [fr

  4. NIMS Observation of Hotspots on Io

    Science.gov (United States)

    1996-01-01

    Io has been imaged by the Near Infrared Mapping Spectrometer (NIMS) on Galileo. The image on the right shows for the first time the distribution of volcanic hotspots on the surface of Io, as seen by NIMS. Three of these hotspots are new discoveries, only detectable with the NIMS instrument. This image was taken during the G1 encounter on June 29 1996. The image on the left shows the same view of Io as seen by the Voyager spacecraft in 1979. At least one dozen hotspots have been identified from this NIMS image. Most of the hotspot locations can be matched with volcanic features on the surface of Io, including the vent area of the active Prometheus plume.The Jet Propulsion Laboratory, Pasadena, CA manages the mission for NASA's Office of Space Science, Washington, DC.This image and other images and data received from Galileo are posted on the World Wide Web, on the Galileo mission home page at URL http://galileo.jpl.nasa.gov.

  5. AEC to Referee, Not Promote, Industry.

    Science.gov (United States)

    1971-10-29

    A major turnabout in the attitude of the Atomic Energy Commission toward the nuclear power industry was signaled last week by the ntew AEC chairman James R. Schlesinger. With patrician froideur, Schlesinger informed a mass gathering of the nuclear power industry at Bal Harbour, Florida, that from henceforth the AEC woLuld act as the referee of nuclear power, not its promoter. Saying he would dispense with the "anecdotes and clumsy jests" customary on such occasions, Schlesinger served notice on the nuclear banqueters that their cozy relationship with the AEC was at an end. The industry should not expect the AEC to fight its battles: it should take its own case to the public-as the Sierra Club does. Nor did the AEC intend to bend the rules in industry's favor. "We have had a fair amount of advice on how to evade the clear mandate of the federal courts. It is advice we did not think proper to accept," Schlesinger said. Even on matters of engineering quality, the diners were told they knew full well they had "reason to blush." Roused out of any postprandial euphoria by this glacial disdain, the industry representatives heard the new chairman announce the following radical upheavals in official AEC philosophy.

  6. NIMS: hotspots on Io during G2

    Science.gov (United States)

    1996-01-01

    The Near Infrared Mapping Spectrometer (NIMS) on the Galileo spacecraft imaged Io at high spectral resolution at a range of 439,000 km (275,000 miles) during the G2 encounter on 7 September 1996. This image shows (on the right) Io as seen in the infrared by NIMS. The image on the left shows the same view from Voyager in 1979. This NIMS image can be compared to the NIMS images from the G1 orbit (June 1996) to monitor changes on Io. The NIMS image is at 4.9 microns, showing thermal emissions from the hotspots. The brightness of the pixels is a function of size and temperature.At least 10 hotspots have been identified and can be matched with surface features. An accurate determination of the position of the hotspot in the vicinity of Shamash Patera is pending. Hotspots are seen in the vicinity of Prometheus, Volund and Marduk, all sites of volcanic plume activity during the Galileo encounters, and also of active plumes in 1979. Temperatures and areas have been calculated for the hotspots shown. Temperatures range from 828 K (1031 F) to 210 K (- 81.4 F). The lowest temperature is significantly higher than the Io background (non-hotspot) surface temperature of about 100 K (-279 F). Hotspot areas range from 6.5 square km (2.5 sq miles) to 40,000 sq km (15,400 sq miles). The hottest hotspots have smallest areas, and the cooler hotspots have the largest areas. NIMS is continuing to observe Io to monitor volcanic activity throughout the Galileo mission.The Galileo mission is managed by the Jet Propulsion Laboratory for NASA's Office of Space Science, Washington, D.C.This image and other images and data received from Galileo are posted on the Galileo mission home page on the World Wide Web at http://galileo.jpl.nasa.gov.

  7. The general solution of a Nim-heap game

    Institute of Scientific and Technical Information of China (English)

    宋林森; 卢澎涛

    2010-01-01

    As a combinatorial one,the game Nim turns out to be extremely useful in certain types of combinatorial game analysis.It has given the general solution of the game a Nim-heap game and the result has proved true.

  8. National Incident Management System (NIMS) Standards Review Panel Workshop Summary Report

    Energy Technology Data Exchange (ETDEWEB)

    Stenner, Robert D.; Kirk, Jennifer L.; Stanton, James R.; Shebell, Peter; Schwartz, Deborah S.; Judd, Kathleen S.; Gelston, Gariann M.

    2006-02-07

    The importance and need for full compliant implementation of NIMS nationwide was clearly demonstrated during the Hurricane Katrina event, which was clearly expressed in Secretary Chertoff's October 4, 2005 letter addressed to the State's governors. It states, ''Hurricane Katrina was a stark reminder of how critical it is for our nation to approach incident management in a coordinated, consistent, and efficient manner. We must be able to come together, at all levels of government, to prevent, prepare for, respond to, and recover from any emergency or disaster. Our operations must be seamless and based on common incident management doctrine, because the challenges we face as a nation are far greater than capabilities of any one jurisdiction.'' The NIMS is a system/architecture for organizing response on a ''national'' level. It incorporations ICS as a main component of that structure (i.e., it institutionalizes ICS in NIMS). In a paper published on the NIMS Website, the following statements were made: ''NIMS represents a core set of doctrine, principles, terminology, and organizational processes to enable effective, efficient and collaborative incident management at all levels. To provide the framework for interoperability and compatibility, the NIMS is based on a balance between flexibility and standardization.'' Thus the NIC is challenged with the need to adopt quality SDO generated standards to support NIMS compliance, but in doing so maintain the flexibility necessary so that response operations can be tailored for the specific jurisdictional and geographical needs across the nation. In support of this large and complex challenge facing the NIC, the Pacific Northwest National Laboratory (PNNL) was asked to provide technical support to the NIC, through their DHS Science and Technology ? Standards Portfolio Contract, to help identify, review, and develop key standards for NIMS compliance. Upon

  9. High-resolution structure of the antibiotic resistance protein NimA from Deinococcus radiodurans

    International Nuclear Information System (INIS)

    Leiros, Hanna-Kirsti S.; Tedesco, Consiglia; McSweeney, Seán M.

    2008-01-01

    In this paper, the 1.2 Å atomic resolution crystal structure of the 5-nitroimidazole antibiotic resistance protein NimA from Deinococcus radiodurans (DrNimA) is presented. Many anaerobic human pathogenic bacteria are treated using 5-nitroimidazole-based (5-Ni) antibiotics, a class of inactive prodrugs that contain a nitro group. The nitro group must be activated in an anaerobic one-electron reduction and is therefore dependent on the redox system in the target cells. Antibiotic resistance towards 5-Ni drugs is found to be related to the nim genes (nimA, nimB, nimC, nimD, nimE and nimF), which are proposed to encode a reductase that is responsible for converting the nitro group of the antibiotic into a nonbactericidal amine. A mechanism for the Nim enzyme has been proposed in which two-electron reduction of the nitro group leads to the generation of nontoxic derivatives and confers resistance against these antibiotics. The cofactor was found to be important in the mechanism and was found to be covalently linked to the reactive His71. In this paper, the 1.2 Å atomic resolution crystal structure of the 5-nitroimidazole antibiotic resistance protein NimA from Deinococcus radiodurans (DrNimA) is presented. A planar cofactor is clearly visible and well defined in the electron-density map adjacent to His71, the identification of the cofactor and its properties are discussed

  10. NIM gas controlled sodium heat pipe

    Science.gov (United States)

    Yan, X.; Zhang, J. T.; Merlone, A.; Duan, Y.; Wang, W.

    2013-09-01

    Gas controlled heat pipes (GCHPs) provide a uniform, stable and reproducible temperature zone to calibrate thermometers and thermocouples, and to realize defining fixed points using a calorimetric method. Therefore, to perform such investigations, a GCHP furnace using sodium as its working fluid was constructed at the National Institute of Metrology (NIM), China. Also, investigations into the thermal characteristics of the NIM gas controlled sodium heat pipe were carried out. The temperature stability over 5 hours was better than ±0.25 mK while controlling the pressure at 111250 Pa. The temperature uniformity within 14 cm from the bottom of the thermometer well was within 0.3 mK. While keeping the pressure stable at the same value, 17 temperature determinations were performed over 14 days, obtaining a temperature reproducibility of 1.27 mK. Additionally, the NIM gas controlled sodium heat pipe was compared with the sodium heat pipe produced by INRiM. The temperature in the INRiM sodium heat pipe operating at 111250 Pa was determined, obtaining a difference of 21 mK with respect to the NIM GCHP. This difference was attributed to sodium impurities, pressure controller capabilities and reproducibility, and instabilities of high temperature standard platinum resistance thermometers (HTSPRTs). Further investigations will be carried out on extending the pressure/temperature range and connecting both GCHPs to the same pressure line.

  11. Explaining implementation behaviour of the National Incident Management System (NIMS).

    Science.gov (United States)

    Jensen, Jessica; Youngs, George

    2015-04-01

    This paper explains the perceived implementation behaviour of counties in the United States with respect to the National Incident Management System (NIMS). The system represents a massive and historic policy mandate designed to restructure, standardise and thereby unify the efforts of a wide variety of emergency management entities. Specifically, this study examined variables identified in the NIMS and policy literature that might influence the behavioural intentions and actual behaviour of counties. It found that three key factors limit or promote how counties intend to implement NIMS and how they actually implement the system: policy characteristics related to NIMS, implementer views and a measure of local capacity. One additional variable-inter-organisational characteristics-was found to influence only actual behaviour. This study's findings suggest that the purpose underlying NIMS may not be fulfilled and confirm what disaster research has long suggested: the potential for standardisation in emergency management is limited. © 2015 The Author(s). Disasters © Overseas Development Institute, 2015.

  12. AEC determines uranium enrichment policy

    International Nuclear Information System (INIS)

    Anon.

    1992-01-01

    The Advisory Committee on Uranium Enrichment of the Atomic Energy Commission (AEC) has submitted a report to AEC chairman concerning the promotion of the introduction of advanced material, high performance centrifuges to replace conventional metallic drum centrifuges, and the development of next generation advanced centrifuges. The report also called for the postponement until around 1997 of the decision whether the development should be continued or not on atomic vapor laser isotope separation (AVLIS) and molecular laser isotope separation (MLIS) processes, as well as the virtual freezing of the construction of a chemical process demonstration plant. The report was approved by the AEC chairman in August. The uranium enrichment service market in the world will continue to be characterized by oversupply. The domestic situation of uranium enrichment supply-demand trend, progress of the expansion of Rokkasho enrichment plant, the trend in the development of gas centrifuge process and the basic philosophy of commercializing domestic uranium enrichment are reported. (K.I.)

  13. A standard digital data busing system for use with nim modules

    International Nuclear Information System (INIS)

    Kirsten, F.A.

    1984-01-01

    A NIM Committee working group has recently completed a specification that defines a standard digital bus for use with NIM modules. The standard bus is based on the General Purpose Instrumentation Bus of IEEE Standard 488. It incorporates a subset of the codes and conventions for the GPIB given in IEEE Standard 728. The standard bus definition also includes specifications for additional features and provisions that are special to the NIM application. The most prominent of these is the set of mnemonics defined for information transfer

  14. Immunoregulation by airway epithelial cells (AECs against respiratory virus infection

    Directory of Open Access Journals (Sweden)

    Yan YAN

    2017-11-01

    Full Text Available The respiratory tract is primary contact site of the body and environment, and it is ventilated by 10-20 thousand liters of air per day. Inevitably, the respiratory system comes into contact with airborne microbes, which contain the disease-causing pathogens. Airway epithelial cells (AECs are known to have innate sensor functions, which are similar to the "professional" immune cells, such as alveolar macrophage and sub- or intra-epithelial dendritic cells (DCs. Thus AECs are able to detect invading microbial danger including different types of respiratory viruses, and mount a potent host response, for example, activating type Ⅰ interferon signaling pathway genes. To avoid chronic inflammation and maintain the immunological homeostasis, the pulmonary system has developed intrinsic mechanisms to control local immune responses. Most recently, the role of AECs in control of local immunity has gained much attention, as 1 AECs express the pattern recognition receptors (PRRs, such as Toll-like receptors, retinoic acid inducible gene Ⅰ (RIG-I-like receptor, and so on, thus AECs are equipped to participate in innate detection of microbial encounter; 2 To keep immunological homeostasis in the respiratory tract, AECs behave not only as innate immune sensors but also as immune modulators in parallel, through modulating the sensitivity of innate immune sensing of both AECs per se and sub- or intra-epithelial immune cells; 3 Loss of modularity capacity of AECs might be involved in the development of chronic airway diseases. In present review, how the AECs act will be intensively discussed in response to respiratory viruses and modulate the local immunity through cis- and trans-factors (direct and indirect factors, as well as the consequence of impairment of this control of local immunity, in the development and exacerbation of airway diseases, such as acute and chronic rhinosinusitis. DOI: 10.11855/j.issn.0577-7402.2017.10.02

  15. NIMS structural materials databases and cross search engine - MatNavi

    Energy Technology Data Exchange (ETDEWEB)

    Yamazaki, M.; Xu, Y.; Murata, M.; Tanaka, H.; Kamihira, K.; Kimura, K. [National Institute for Materials Science, Tokyo (Japan)

    2007-06-15

    Materials Database Station (MDBS) of National Institute for Materials Science (NIMS) owns the world's largest Internet materials database for academic and industry purpose, which is composed of twelve databases: five concerning structural materials, five concerning basic physical properties, one for superconducting materials and one for polymers. All of theses databases are opened to Internet access at the website of http://mits.nims.go.jp/en. Online tools for predicting properties of polymers and composite materials are also available. The NIMS structural materials databases are composed of structural materials data sheet online version (creep, fatigue, corrosion and space use materials strength), microstructure for crept material database, Pressure vessel materials database and CCT diagram for welding. (orig.)

  16. A new electronic circuit for NIM rack power supply

    International Nuclear Information System (INIS)

    Toledo, Fabio de; Domienikan, Claudio; Zahn, Guilherme S.

    2013-01-01

    A new and useful electronic circuit designed to substitute the old power supply of IPEN model PM 1212 Nuclear Instrument Modules (NIM) racks is presented. Originally, these NIM racks were projected by IPEN workshop at 1974 to be used in nuclear research laboratories. The PM1212 provided mounting space and power sources for up to 12 standard nuclear electronic modules and power supply regulated DC voltages of ±24V (2A), ±12V (4A) and unregulated AC 117V (0.5A). Currently, several of these NIM racks are not in use because the electronic components of the original design have become obsolete and are no longer manufactured. The new electronic circuit provides the same original voltages adjusted in the single circuit and, additionally, ±6V. The new power supply was designed and constructed at IPEN-CNEN/SP by employing modern national components and expertise. (author)

  17. A new electronic circuit for NIM rack power supply

    Energy Technology Data Exchange (ETDEWEB)

    Toledo, Fabio de; Domienikan, Claudio; Zahn, Guilherme S., E-mail: fatoledo@ipen.br, E-mail: clanikan@ipen.br, E-mail: gzahn@ipen.br [Intituto de Pesquisas Energeticas e Nucleares (IPEN-CNEN/SP), Sao Paulo, SP (Brazil)

    2013-07-01

    A new and useful electronic circuit designed to substitute the old power supply of IPEN model PM 1212 Nuclear Instrument Modules (NIM) racks is presented. Originally, these NIM racks were projected by IPEN workshop at 1974 to be used in nuclear research laboratories. The PM1212 provided mounting space and power sources for up to 12 standard nuclear electronic modules and power supply regulated DC voltages of ±24V (2A), ±12V (4A) and unregulated AC 117V (0.5A). Currently, several of these NIM racks are not in use because the electronic components of the original design have become obsolete and are no longer manufactured. The new electronic circuit provides the same original voltages adjusted in the single circuit and, additionally, ±6V. The new power supply was designed and constructed at IPEN-CNEN/SP by employing modern national components and expertise. (author)

  18. South Africa and the RERTR programme. Current status. An AEC perspective

    International Nuclear Information System (INIS)

    Ball, G.

    1999-01-01

    The Atomic Energy Corporation (AEC) of South Africa fully endorses the principles of the RERTR programme. To this end in 1994 the AEC, together with Argonne National Laboratory (ANL), undertook a study into the feasibility of converting the SAFARI-1 reactor to LEU silicide fuel. More details are given. Due to the commercial pressures on the AEC at that time, the AEC decided not to convert SAFARI-1 to LEU silicide fuel. The AEC did, however, undertake to reevaluate the situation periodically. Five years have passed since the detailed study of 1994 and the changing conditions now warrant another detailed study taking into account the current situation. A brief historical background is given on the RERTR activities in South Africa since 1993 followed by a summary of the current situation

  19. NIMS EXPERIMENT DATA RECORDS: GASPRA/IDA ENCOUNTERS

    Data.gov (United States)

    National Aeronautics and Space Administration — NIMS Experiment Data Record (EDR) files contain raw data from the Galileo Orbiter Near-Infrared Mapping Spectrometer (CARLSONETAL1992). This raw data requires...

  20. Thermal stability, swelling behavior and CO 2 absorption properties of Nanoscale Ionic Materials (NIMs)

    KAUST Repository

    Andrew Lin, Kun-Yi

    2014-11-11

    © The Royal Society of Chemistry 2015. Nanoscale Ionic Materials (NIMs) consist of a nanoscale core, a corona of charged brushes tethered on the surface of the core, and a canopy of the oppositely charged species linked to the corona. Unlike conventional polymeric nanocomposites, NIMs can display liquid-like behavior in the absence of solvents, have a negligible vapor pressure and exhibit unique solvation properties. These features enable NIMs to be a promising CO2 capture material. To optimize NIMs for CO2 capture, their structure-property relationships were examined by investigating the roles of the canopy and the core in their thermal stability, and thermally- and CO2-induced swelling behaviors. NIMs with different canopy sizes and core fractions were synthesized and their thermal stability as well as thermally- and CO2-induced swelling behaviors were determined using thermogravimetry, and ATR FT-IR and Raman spectroscopies. It was found that the ionic bonds between the canopy and the corona, as well as covalent bonds between the corona and the core significantly improved the thermal stability compared to pure polymer and polymer/nanofiller mixtures. A smaller canopy size and a larger core fraction led to a greater enhancement in thermal stability. This thermal stability enhancement was responsible for the long-term thermal stability of NIMs over 100 temperature swing cycles. Owing to their ordered structure, NIMs swelled less when heated or when they adsorbed CO2 compared to their corresponding polymers. This journal is

  1. Thermal stability, swelling behavior and CO 2 absorption properties of Nanoscale Ionic Materials (NIMs)

    KAUST Repository

    Andrew Lin, Kun-Yi; Park, Youngjune; Petit, Camille; Park, Ah-Hyung Alissa

    2014-01-01

    © The Royal Society of Chemistry 2015. Nanoscale Ionic Materials (NIMs) consist of a nanoscale core, a corona of charged brushes tethered on the surface of the core, and a canopy of the oppositely charged species linked to the corona. Unlike conventional polymeric nanocomposites, NIMs can display liquid-like behavior in the absence of solvents, have a negligible vapor pressure and exhibit unique solvation properties. These features enable NIMs to be a promising CO2 capture material. To optimize NIMs for CO2 capture, their structure-property relationships were examined by investigating the roles of the canopy and the core in their thermal stability, and thermally- and CO2-induced swelling behaviors. NIMs with different canopy sizes and core fractions were synthesized and their thermal stability as well as thermally- and CO2-induced swelling behaviors were determined using thermogravimetry, and ATR FT-IR and Raman spectroscopies. It was found that the ionic bonds between the canopy and the corona, as well as covalent bonds between the corona and the core significantly improved the thermal stability compared to pure polymer and polymer/nanofiller mixtures. A smaller canopy size and a larger core fraction led to a greater enhancement in thermal stability. This thermal stability enhancement was responsible for the long-term thermal stability of NIMs over 100 temperature swing cycles. Owing to their ordered structure, NIMs swelled less when heated or when they adsorbed CO2 compared to their corresponding polymers. This journal is

  2. NIMS: hotspots on Io during G2 (continued)

    Science.gov (United States)

    1997-01-01

    This is another Near Infrared Mapping Spectrometer (NIMS) image of Io, taken during the G2 encounter in September 1996. This is a dayside image of Io (on the right) against the clouds of Jupiter (the blue background). On the left is a Voyager mosaic of Io with the same viewing geometry for comparison purposes. This NIMS data set has been processed to highlight the positions of hot spots on the surface of Io. At least 11 can be seen. Two of the hotspots are newly discovered by the NIMS instrument. Others correspond to sites of plume eruptions and volcanic calderas and volcanic flows. This image can be compared with the SSI image P-47971 released on October 23, 1996, which was taken almost exactly the same position.The Jet Propulsion Laboratory, Pasadena, CA manages the mission for NASA's Office of Space Science, Washington, DC.The Jet Propulsion Laboratory, Pasadena, CA manages the mission for NASA's Office of Space Science, Washington, DC.This image and other images and data received from Galileo are posted on the World Wide Web, on the Galileo mission home page at URL http://galileo.jpl.nasa.gov.

  3. STRENGTHENING COUNSELORS SPIRITUALITY IN FACING ASEAN ECONOMIC COMMUNITY (AEC

    Directory of Open Access Journals (Sweden)

    Muhamad Rozikan

    2017-05-01

    Full Text Available There is an anxiety to face ASEAN Economic Community (AEC. This is natural reaction when we see our readiness to face competition compared with other ASEAN countries. Such manner already exists since the inception of ASEAN in 1967. The anxiety would be a reasonable thing to the enactment of MEA, considering not all the people know what the MEA is. The survey results indicate that the stakeholder both the central government, local government, academia, and society in this country is still relatively have low understanding and knowledge about the ASEAN Economic community (AEC. It is ironic, other ASEAN countries has been intensely preparing steps needed to face AEC, while the majority of the Indonesian people do not know what it is. Modern life along with science, technology and economic progress experienced by Western nations turned out to have caused various situations of life that does not give happiness and a growing sense of inner emptiness. The counselor existence in the counseling today, should be able to develop its human resources, so it is able to answer the problem to encounter global competition of ASEAN Economic Community (AEC. Spiritual counseling and guidance counselors as an alternative solution to deal with the AEC which fully loaded with interest and ability/professionalism in various occupations faced.

  4. Nuclear criticality safety. Chapter 0530 of AEC manual

    International Nuclear Information System (INIS)

    2006-01-01

    The programme objectives of this chapter of the U.S. Atomic Energy Commission manual on nuclear criticality safety are to protect the health and safety of the public and of the government and contractor personnel working in plants that handle fissionable material and to protect public and private property from the consequences of a criticality accident occurring in AEC-owned plants and other AEC-contracted activities involving fissionable materials

  5. A new multi-purpose NIM module

    International Nuclear Information System (INIS)

    Dong Binjiang; Wang Congrong; Du Chunxiang.

    1992-01-01

    The authors briefly state the function, character and main technique performance of a new multi-purpose NIM interposition (NI01) developed recently. This interposition uses 8031 single-chip microprocessors as the kernel and is multi-purpose, reliable and convenient. Especially, it is suitable for training teaching and scientific researching

  6. The NIM alanine-EPR dosimetry system: its application in NDAS programme and others

    International Nuclear Information System (INIS)

    Gao Jun-Cheng

    1999-01-01

    In 1983, National Institute of Metrology (NIM) began to study alanine-EPR dosimetry system. From 1988 on, the system has been used as a transfer standard to launch into the National Dose Assurance Service (NDAS) programme for cobalt-60 facilities in China. In this paper, the eleven years implementation of NDAS programme are presented by statistics. In 1991, under an IAEA coordinated research programme, NIM had studied to extend the range of the system to therapy level. In recent years, the NIM in cooperation with other institutes has been developing film-alanine dosimeter for electron beam dosimetry. (author)

  7. AEC testing in a CR environment

    International Nuclear Information System (INIS)

    McLeod, R.

    2004-01-01

    Full text: Testing of x-ray machine automatic exposure control (AEC) functionality for varying kVp and patient thickness is a fundamental health physics check. Current test protocols tend to be based on testing in a film environment using film optical density as the measure of conformance. With the move into the digital x-ray image age with the use of computed radiography (CR) and digital radiography (DR) equipment and its associated image storage and retrieval system (PACS) a new AEC testing protocol is required. All CR systems provide a dose assessment tool (called Exposure Index or EI by Kodak) that could be used as a surrogate for optical density. However this work aims to derive an efficient means of assessing the functioning of the AEC of x-ray machines in a CR environment using dose measurement alone. This would eliminate the need to process the many image plates normally required for AEC testing in order to obtain and analyse the exposure measure from the CR system. The EI, and other brand's equivalents, is calibrated for a given condition (for Kodak 80kVp 0.5mmCu + 1mmAl). In order to use dose measurement alone the relationship between EI and dose must be known for varying kVp and patient thicknesses (represented by a perspex phantom). This will depend on the response of the CR plate to varying beam energies. This was assessed using a series of paired exposures at various kVp and perspex thicknesses. In the first exposure of each pair a Kodak CR plate was used, processed in the normal way, and the EI noted. In a second identical exposure an Innovision 35050A pancake ionization chamber was placed in the bucky tray within a specially modified film cassette and the dose measured. Over the 50-125kVp range of clinical use the kV response of the Kodak PSP's shown below is essentially flat for a set dose to the image plate and filtered using the standard Kodak method of 0.5mmCu + 1mmAl. Similar data will be presented showing this relationship using a perspex

  8. AEC review 1988

    International Nuclear Information System (INIS)

    1988-10-01

    Activities of the Atomic Energy Corporation of South Africa Limited (AEC) are reviewed. The activities of each of the six Management Units, namely Uranium Processing, Uranium Enrichment, Research and Development, Engineering, Human Resources and Finance and Commercial Affairs, are discussed. The Uranium Processing Unit includes the two major production programmes, viz. UF6 production and fuel-element fabrication. The objective of the Uranium Enrichment Management Unit is the supply of enriched uranium. The unit operates two uranium enrichment plants, the semicommercial Z Plant and the pilot plant. The Research and Developement Unit is structured into 7 programmes which are related mainly to the fuel cycle. It concentrates on facets of the nuclear fuel cycle, by-products of the nuclear industry and research services, as well as transfer of specialized technology to private industry. The Engineering Unit includes Engineering Services, Technical Services, Nuclear Waste Technology which involves the handling and disposal of all radioactive waste in South Africa, Central Quality Services, and Safety. The Human Resources Management Unit is divided in four functional units, viz. Manpower Services, Labour Relations, Training and Development and Manpower Specialized Services. The Unit Finance and Commercial Affairs consists of Financial and Accounting Services, Management Services, Corporate Information and Marketing and Commercial Services. A list of products and services delivered by the AEC is included as well as a list of publications by staff members

  9. List of unrestricted NIM publications issued from 1966 to 1980

    International Nuclear Information System (INIS)

    Glen, H.W.

    1980-01-01

    This publication lists the 742 unrestricted reports, 337 papers, 26 patents, and 4 other technical publications that were issued as publications of the National Institute for Metallurgy (NIM) from 1966 (the year of its inception) to 1st April 1980. For ease of reference these publications are also classified under research topics. Also included are details of the 2 periodicals issued by NIM and a list of the current miscellaneous publications of the Institute, which include the annual report, and brochures and leaflets of various kinds [af

  10. Small-for-Size Liver Transplantation Increases Pulmonary Injury in Rats: Prevention by NIM811

    Directory of Open Access Journals (Sweden)

    Qinlong Liu

    2012-01-01

    Full Text Available Pulmonary complications after liver transplantation (LT often cause mortality. This study investigated whether small-for-size LT increases acute pulmonary injury and whether NIM811 which improves small-for-size liver graft survival attenuates LT-associated lung injury. Rat livers were reduced to 50% of original size, stored in UW-solution with and without NIM811 (5 μM for 6 h, and implanted into recipients of the same or about twice the donor weight, resulting in half-size (HSG and quarter-size grafts (QSG, respectively. Liver injury increased and regeneration was suppressed after QSG transplantation as expected. NIM811 blunted these alterations >75%. Pulmonary histological alterations were minimal at 5–18 h after LT. At 38 h, neutrophils and monocytes/macrophage infiltration, alveolar space exudation, alveolar septal thickening, oxidative/nitrosative protein adduct formation, and alveolar epithelial cell/capillary endothelial apoptosis became overt in the lungs of QSG recipients, but these alterations were mild in full-size and HSG recipients. Liver pretreatment with NIM811 markedly decreased pulmonary injury in QSG recipients. Hepatic TNFα and IL-1β mRNAs and pulmonary ICAM-1 expression were markedly higher after QSG transplantation, which were all decreased by NIM811. Together, dysfunctional small-for-size grafts produce toxic cytokines, leading to lung inflammation and injury. NIM811 decreased toxic cytokine formation, thus attenuating pulmonary injury after small-for-size LT.

  11. Volcanism on Io: The Galileo NIMS Io Thermal Emission Database (NITED)

    Science.gov (United States)

    Davies, A. G.; Veeder, G. J.; Matson, D. L.; Johnson, T. V.

    2011-12-01

    In order to determine the magnitude of thermal emission from Io's volcanoes and variability with time at local, regional and global scales, we have calculated the 4.7 or 5 μm radiant flux for every hot spot in every Galileo Near Infrared Mapping Spectrometer (NIMS) observation obtained during the Galileo mission between June 1996 and October 2001. The resulting database contains over 1000 measurements of radiant flux, corrected for emission angle, range to target, and, where necessary, incident sunlight. Io's volcanoes produce the most voluminous and most powerful eruptions in the Solar System [1] and NIMS was the ideal instrument for measuring thermal emission from these volcanoes (see [1, 2]). NIMS covered the infrared from 0.7 to 5.2 μm, so measurement of hot spot thermal emission at ~5 μm was possible even in daytime observations. As part of a campaign to quantify magnitude and variability of volcanic thermal emission [1, 3-5] we examined the entire NIMS dataset (196 observations). The resulting NIMS Io Thermal Emission Database (NITED) allows the charting of 5-μm thermal emission at individual volcanoes, identifying individual eruption episodes, and enabling the comparison of activity at different hot spots [e.g., 6] and different regions of Io. Some ionian hot spots were detected only once or twice by NIMS (e.g., Ah Peku Patera, seen during I32), but most were detected many times (e.g., Culann, Tupan and Zamama, [6]). For example, the database contains over 40 observations of Loki Patera (some at high emission angle, and two partial observations). There are 55 observations of Pele. The 27 nighttime observations of Pele show a remarkably steady 5-μm radiant flux of 35 ± 12 GW/μm. There are 34 observations of Pillan, which erupted violently in 1997. Although in many observations low spatial resolution makes it difficult to separate hot spot pairs such as Susanoo Patera and Mulungu Patera; Tawhaki Patera and Hi'iaka Patera; and Janus Patera and Kanehekili

  12. Exploring the Client–AEC Interface in Building Lifecycle Integration

    Directory of Open Access Journals (Sweden)

    John M. Kamara

    2013-07-01

    Full Text Available The creation and management of buildings over their lifecycle involves the cooperation of many organizations, which broadly fall into a client domain and AEC (architecture, engineering, construction domain. While this mix of expertise is essential, the ineffective management of the boundaries between these organizations can undermine building lifecycle performance. This paper explores client–AEC interactions at the project development and handover stages, with a view to discovering insights into client–AEC interface management for effective building lifecycle integration (BLI. The concept of boundary objects provided the theoretical framework to discuss findings from two case studies on the project development phase of a private finance initiative project, and the asset development process in a repeat client organization. The findings suggest that there are different emphases in boundary crossing activities at different stages, with boundary roles that relate to decision-making and authority to commit resources being more relevant at the project development stage, whereas the need to explain meanings appear to be more relevant at the handover stage. AEC professionals in client organizations play a crucial role in bridging knowledge boundaries about buildings, but this professional/functional strand to BLI needs to be effectively managed alongside the organizational boundaries, since the authority to resource BLI efforts resides within organizations.

  13. BIM Investment, Returns, and Risks in China’s AEC Industries

    OpenAIRE

    Jin, R; Hancock, CM; Tang, L; Wanatowski, D

    2017-01-01

    Building information modeling (BIM), the emerging digital technology, is undergoing increasing application in developing countries including China. Both the governmental policy and industry motivation have indicated that BIM is becoming the mainstream innovation in China’s construction industry. Nevertheless, one major concern lies in the uncertainty of BIM investment for architecture, engineering, and construction (AEC) firms. Specifically, AEC firms should have the knowledge of areas BIM in...

  14. The Adaptive Ecosystem Climatology (AEC): Design and Development

    Science.gov (United States)

    deRada, S.; Penta, B.; McCarthy, S.; Gould, R. W., Jr.

    2016-02-01

    The concept of ecosystem-based management (EBM), recently introduced to rectify the shortcomings of single-species management policies, has been widely accepted as a basis for the conservation and management of natural resources. In line with NOAA's Integrated Ecosystem Assessment (IEA) Program, EBM is an integrated approach that considers the entire ecosystem and the interactions among species rather than focusing on individual components. This integrative approach relies on heterogeneous data, physical as well as biogeochemical data, among many others. Relative to physical data, however, marine biogeochemical records, also critical in IEA and EBM, are still lacking, both in terms of mature models and in terms of observational data availability. TheAdaptive Ecosystem Climatology (AEC) was conceived as a novel approach to address these limitations, mitigating the shortcomings of the individual components and combining their strengths to enhance decision-making activities. AEC is designed on the concept that a high-frequency climatology can be used as a baseline into which available observational data can be ingested to produce a higher accuracy product. In the absence of observations, the climatology acts as a best estimate. AEC was developed using a long-term simulation of a coupled biophysical numerical model configured for the Gulf of Mexico. Using the model results, we constructed a three-dimensional, dynamically balanced, gridded, static climatology for each calendar day. Using this `static' climatology as a background `first guess', observations from a particular date are ingested via optimal interpolation to `nudge' the climatology toward current conditions, thus providing representative fields for that date (adaptive climatology). With this adaptive approach, AEC can support a variety of EBM objectives, from fisheries, to resource management, to coastal resilience.

  15. NIMS EXPERIMENT DATA RECORDS: SL-9 COMET IMPACT WITH JUPITER

    Data.gov (United States)

    National Aeronautics and Space Administration — NIMS Experiment Data Record (EDR) files contain raw data from the Galileo Orbiter Near-Infrared Mapping Spectrometer (CARLSONETAL1992). This raw data requires...

  16. A comparison of irradiance responsivity and thermodynamic temperature measurement between PTB and NIM

    International Nuclear Information System (INIS)

    Lu, X.; Yuan, Z.; Anhalt, K.; Taubert, R. D.

    2013-01-01

    This paper describes a comparison between PTB and NIM in the field of absolute spectral-band radiometry and thermodynamic temperature measurement. For the comparison a NIM made interference filter radiometer with a centre wavelength of 633 nm was taken to PTB. The filter radiometer was calibrated at NIM and PTB with respect to spectral irradiance responsivity. For the integral value in the band-pass range an agreement of 0.1% was observed in both calibrations. In a next step, the 633 nm filter radiometer was used to measure the temperature of a high-temperature blackbody in comparison to an 800 nm filter radiometer of PTB in the temperature range between 1400 K and 2750 K. The thermodynamic temperature measured by the two filter radiometers agreed to within 0.2 K to 0.5 K with an estimated measurement uncertainty ranging between 0.1 K and 0.4 K (k=1)

  17. Design and realization of an AEC&AGC system for the CCD aerial camera

    Science.gov (United States)

    Liu, Hai ying; Feng, Bing; Wang, Peng; Li, Yan; Wei, Hao yun

    2015-08-01

    An AEC and AGC(Automatic Exposure Control and Automatic Gain Control) system was designed for a CCD aerial camera with fixed aperture and electronic shutter. The normal AEC and AGE algorithm is not suitable to the aerial camera since the camera always takes high-resolution photographs in high-speed moving. The AEC and AGE system adjusts electronic shutter and camera gain automatically according to the target brightness and the moving speed of the aircraft. An automatic Gamma correction is used before the image is output so that the image is better for watching and analyzing by human eyes. The AEC and AGC system could avoid underexposure, overexposure, or image blurring caused by fast moving or environment vibration. A series of tests proved that the system meet the requirements of the camera system with its fast adjusting speed, high adaptability, high reliability in severe complex environment.

  18. NIMS and Empa announce STAM collaboration

    Science.gov (United States)

    Yoshida, Toyonobu; Krug, Harald F.

    2014-02-01

    In January 2014, the Swiss Federal Laboratories for Materials Science and Technology (Empa) joined the National Institute for Materials Science (NIMS) in collaborative activities on Science and Technology of Advanced Materials (STAM). STAM was founded in 2000. In 2005 NIMS took over the management of its peer review and financial systems, resulting in a continuous rise of the impact of the journal. Empa will provide further support for the editorial management of STAM. In particular, it will establish a European office in Switzerland and reinforce the Editorial Board. From this point of view, I am pleased and excited to have new colleagues from Empa on our Editorial Board, and I believe that this collaboration will bring us a remarkable improvement in the international visibility of STAM and increase the number of paper submissions from Europe. It will expand the topics covered in the journal from traditional fields of materials science with a focus on energy and environmental issues to medical and bioengineering applications, where Empa has a significant expertise. I firmly believe that Empa's participation in publishing STAM will reinforce its position as an open-access journal with a global audience. Together with my colleagues, Yoshio Sakka (NIMS) and Shu Yamaguchi (University of Tokyo), I welcome Harald F Krug as the new Co-Editor-in-Chief of STAM. I am also pleased to learn that the year 2014 not only marks the 15th anniversary of STAM, but also the 150th anniversary of the establishment of diplomatic relations between Japan and Switzerland. Toyonobu Yoshida Advances in materials science are key for the sustainable development of our society. That is why, starting from January 2014, Empa, the Swiss Federal Laboratories for Materials Science and Technology, have engaged in an entirely new field of activity: scientific publishing. As mentioned above, Empa joined NIMS in the publishing of STAM. We have a clear-cut goal in mind: we want to support our sister

  19. Rendimento e Características Físicas dos Óleos de Nim (Azadirachta indica e Mamona (Ricinus communis

    Directory of Open Access Journals (Sweden)

    Juarez Benigno Paes

    Full Text Available A pesquisa objetivou avaliar o rendimento e a viscosidade de óleos de nim (Azadirachta indica e mamona (Ricinus communis. Os frutos de nim foram coletados no Núcleo de Pesquisa do Semiárido, em Patos, Paraíba, e os de mamona, às margens do Rio Espinharas, Patos e em Igaracy, Paraíba. Os frutos foram beneficiados no Laboratório de Tecnologia de Produtos Florestais, em Patos. Foram retiradas amostras de sementes para a determinação do teor de umidade e do rendimento em óleos. Os óleos foram extraídos com álcool etílico absoluto e empregados no preparo de soluções com os óleos de nim e mamona. Determinaram-se a densidade e a viscosidade das soluções. A mamona teve menor teor de umidade e rendimento em óleo que o nim. A densidade e a viscosidade do óleo de nim foram menores que o da mamona. Uma maior quantidade de óleos de mamona proporcionou aumento na densidade e na viscosidade das soluções preparadas.

  20. MODELAGEM SISTÊMICA DE PROJETOS DE AEC EM UML

    Directory of Open Access Journals (Sweden)

    Rita Cristina Ferreira

    2007-11-01

    Full Text Available O uso intensivo de Sistemas de Informação é uma possível solução para a integração das atividades de projeto em AEC, permitindo que decisões sejam tomadas ainda na fase de projeto e, conseqüentemente, evitando-se retrabalhos em obra. Neste sentido, esforços têm sido realizados para padronizar conceitos e terminologias de AEC, permitindo a troca e armazenagem de informações, como a norma ISO 12006-2 e os padrões estabelecidos pelo IFC. Ambas são baseadas na linguagem EXPRESS, assim como é o padrão industrial STEP. Entretanto, as representações de informação usadas na indústria de produtos não são as mais adequadas para a Engenharia de Software, responsável pelo desenvolvimento de Sistemas de Informação, onde as representações semânticas envolvem não somente a representação estrutural da informação, mas também a representação comportamental. Este artigo contribui com uma visão de implementação em UML da informação de um projeto de AEC e tornam explícitas, sob a ótica do desenvolvimento de software, as relações semânticas existentes. Os resultados desta pesquisa foram obtidos através da realização de um estudo de caso de projeto de produção em CAD 3D dos subsistemas alvenaria e revestimento para um edifício residencial. A partir das observações do estudo de caso foi feita a modelagem em UML dos objetos pertinentes. O principal resultado obtido foi a representação explícita das interfaces entre objetos AEC.

  1. Development of a NIM module for time-to-digital conversion

    International Nuclear Information System (INIS)

    Lin Yanchang; Wang Xiaobin; Chen Shaomin; Gao Yuanning; Jiang Chunhua; Qian Wenbin

    2008-01-01

    A developed single slot wide NIM module for time-to-digital conversion (TDC) is presented in this paper. This TDC module consists of a CPLD based double edge trigger counter with logic function circuit, a high speed comparator based NIM-to-TTL logic level converter, a processor ARM based data access and communication control unit, and voltage regulators for power supply. There are two input groups available, separately for accepting start and stop signal between two input ports or just from the same input port in sequence. With a 50 MHz reference clock, the available input ranges from 0 to 81.91 μs, and the resolution can reach 10 ns level. This module was tested in a muon lifetime measurement experiment, showing good linearity, simple configuration, low power consumption, good reliability, low cost, and easy upgrade as well. (authors)

  2. Examination of CT-AEC when the positioning changes after planning of CT scanning

    International Nuclear Information System (INIS)

    Esaki, Tooru; Yamazaki, Shoichi

    2009-01-01

    CT-automatic exposure control (AEC) controls tube current collecting information of the subject from positioning shooting. Because of this, we consider that CT-AEC does not get to operate properly if the body position of the test subject changes after the positioning shooting. However, we often experience in body positions of test subjects after the positioning shooting. In cases like this, we measured by using a phantom again to see how they affect the tube current value and standard deviation (SD) value comparing them to the normal scan where a body position does not change. As a result of the measurement, there was an impact on CT-AEC that optimization of tube current becomes insufficient if the body position of a test subject changes. As the image quality is deteriorated and radiation exposure increases because of this, taking positioning shooting again is required on the part of users and it's desirable on the part of manufacturers to develop CT-AEC that can be controlled with high accuracy. (author)

  3. Bilateral Comparison Between NIM and NMC Over the Temperature Range from 83.8058 K to 692.677 K

    Science.gov (United States)

    Sun, Jianping; Ye, Shaochun; Kho, Haoyuan; Zhang, Jintao; Wang, Li

    2015-08-01

    A bilateral comparison of local realization of the International Temperature Scale of 1990 between the National Institute of Metrology (NIM) and National Metrology Centre (NMC) was carried out over the temperature range from 83.8058 K to 692.677 K. It involved six fixed points including the argon triple point, the mercury triple point, the triple point of water, the melting point of gallium, the freezing point of tin, and the freezing point of zinc. In 2009, NMC asked NIM to participate in a bilateral comparison to link the NMC results to the Consultative Committee for Thermometry Key Comparison 3 (CCT-K3) and facilitate the NMC's calibration and measurement capabilities submission. This comparison was agreed by NIM and Asia Pacific Metrology Programme in 2009, and registered in the Key Comparison Database in 2010 as CCT-K3.2. NMC supplied two fused silica sheath standard platinum resistance thermometers (SPRTs) as traveling standards. One of them was used at the Ga, Sn, and Zn fixed points, while the other one was used at the Ar and Hg fixed points. NMC measured them before and after NIM measured them. During the comparison, a criterion for the SPRT was set as the stability at the triple point of water to be less than 0.3 mK. The results for both laboratories are summarized. A proposal for linking the NMC's comparison results to CCT-K3 is presented. The difference between NMC and NIM and the difference between NMC and the CCT-K3 average reference value using NIM as a link are reported with expanded uncertainties at each measured fixed point.

  4. Computerized CAMAC and NIM module library

    International Nuclear Information System (INIS)

    Pope, G.F.; McDonald, R.J.

    1990-08-01

    The Lawrence Berkeley Laboratory owns a large number of CAMAC and NIM modules which can be connected together to form data acquisition systems used in experiments. Many of these modules are contained in ''pools'' for common usage. This paper describes a system of storage and inventory control that allows easy check-out and check-in of the modules utilizing networked Macintosh computers, FoxBase+/Mac software, and bar-code technology. It also provides search capability for the user and tracking capability for the pool administrator. This inventory system has applications to any pool of items that are routinely loaned. 8 figs

  5. Crescimento, esporulação e viabilidade de fungos entomopatogênicos em meios contendo diferentes concentrações do óleo de nim (Azadirachta indica

    Directory of Open Access Journals (Sweden)

    Marques Renata Paro

    2004-01-01

    Full Text Available A associação de extratos de origem vegetal com fungos entomopatogênicos pode aumentar a eficiência do controle biológico de pragas, reduzir custos e impactos ambientais. No presente trabalho, avaliou-se, através da concentração inibitória mínima, o efeito do óleo de nim (NIM-I-GO sobre o crescimento, esporulação e viabilidade de Metarhizium anisopliae, Beauveria bassiana e Paecilomyces farinosus. Utilizou-se o meio BDA, contendo diferentes concentrações de óleo de nim (C1: 5% de óleo de nim, e sucessivamente concentrações iguais a fraction one-half da concentração anterior, até C11: 0,0048% de óleo de nim. O óleo de nim reduziu o crescimento de colônias de B. bassiana e P. farinosus, que não diferiram significativamente do controle apenas na concentração C11, mas para M. anisopliae o mesmo efeito foi observado com 0,039% de óleo de nim (C8. A esporulação também foi significativamente reduzida pelo óleo de nim, exceto na concentração C11 para B. bassiana; contudo, não se verificou efeito do óleo na viabilidade de esporos dos fungos.

  6. Report on NIM-NMC bilateral comparison: SPRT calibration comparison from -190°C to 420°C

    Science.gov (United States)

    Sun, Jianping; Ye, Shaochun; Wang, Li; Zhang, Jintao; Kho, Haoyuan

    2016-01-01

    A bilateral comparison of local realization of the International temperature scale of 1990 (ITS-90) between National Institute of Metrology (NIM) and National Metrology Centre (NMC) was carried out over the temperature range from -190°C to 420°C. It involved six fixed points including the argon triple point, the mercury triple point, the triple point of water, the melting point of gallium, the freezing point of tin and the freezing point of zinc. In 2009, NMC asked NIM to participate in a bilateral comparison to link the NMC results to the Consultative Committee for Thermometry Key comparison 3 (CCT-K3) and facilitate the NMC's Calibration and measurement capabilities (CMCs) submission. This comparison was agreed by NIM and Asia Pacific Metrology Programme (APMP) in 2009, and registered in the Key Comparison Database (KCDB) in 2010 as CCT-K3.2. NMC supplied two 25 Ω fused silica sheath standard platinum resistance thermometers (SPRTs) as traveling standards. One of them was used at the Ga, Sn and Zn fixed points, while the other one was used at the Ar and Hg fixed point. NMC measured them before and after NIM measurement. During the comparison, a criterion for the SPRT was set as the stability at the triple point of water to be less than 0.3 mK. The results for both laboratories are summarized. A proposal for linking the NMC's comparison results to CCT-K3 is presented. The difference between NMC and NIM and the difference between NMC and the CCT-K3 Average Reference Value (ARV) using NIM as a link are reported with expanded uncertainties at each measured fixed point. Main text To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by the CCT, according to the provisions of the CIPM Mutual Recognition Arrangement (CIPM MRA).

  7. Basic data report for Drillhole AEC 7 (Waste Isolation Pilot Plant - WIPP)

    International Nuclear Information System (INIS)

    1983-01-01

    AEC 7 is a borehole drilled in western Lea County, New Mexico, in section 31, T.21S.,R.32E. AEC 7 was drilled to 3918 feet in 1974 by Oak Ridge National Laboratory; Sandia deepened the hole to 4732 ft in 1979. The borehole provided stratigraphic and lithologic information in the initial and final drilling. The borehole was used extensively for tests of borehole plugs and plugging operations. AEC 7 penetrated, in descending order, Holocene sands and Mescalero caliche (8 ft), Santa Rosa Sandstone (109 ft), Dewey Lake Red Beds (542 ft), Rustler Formation (325 ft), Salado Formation (2014 ft), Castile Formation (1521 ft), and the upper Bell Canyon Formation (197 ft). Cores were obtained from much of the borehole. An extensive suite of geophysical logs provides information on stratigraphy, lithology, and structure. Beds were in normal stratigraphic sequence and without structural deformation except in the lower Castile. Anhydrite II and Halite II appear to be repeated in the borehole. This section was penetrated during deepening by Sandia; the structural complication is consistent with deformation found nearby in ERDA 6. The potential site on which AEC 7 is located was abandoned in 1976 after ERDA 6 was drilled. The WIPP is a demonstration facility for the disposal of transuranic (TRU) waste from defense programs. The WIPP will also provide a research facility to investigate the interactions between bedded salt and high level wastes

  8. Vitality Of Village Umkm In The Arena Of Asean Economic Community (Aec

    Directory of Open Access Journals (Sweden)

    Dhanny Septimawan Sutopo

    2016-12-01

    Full Text Available A horizon of expectation seems to be much brighter when the regional cooperation among the Southeast Asian countries intensify due to their meeting commitment of integration. The culmination of the regional cooperation commitment in Southeast Asia is an agreement to become a solid community within the framework of the Asean Community. One aim of the Asean Community is to form a joint economic community among the countries in Southeast Asia, commonly known as the Asean Economic Community (AEC. AEC opens space for the flow of goods and services from ASEAN member countries freely, including items that have been developed by Usaha Mikro Kecil dan Menengah (UMKM – Micro Small and Medium Enterprises. In Indonesia, especially in Malang, UMKM provide the foundation of the regional economic development. The implementation of AEC will slowly and surely give implications to UMKM and regional economy, more specifically the areas with less attention preparing for UMKM to face the Southeast Asian regional free market. It is an early gate to determine whether the position of this proved-to-be-resilient economic actors (read: UMKM will be involved or will be squashed to be a spectator when the other countries of the region make Indonesia as a new trading arena. This research will conduct a preliminary assessment towards the local government’s innovation in facing the implementation of AEC, primarily that relates to organizing UMKM at the local/village level. The purpose of this study is to gain an understanding in greater detail in accordance with the local government's response and strategies in Malang Raya to prepare village UMKM in dealing with the implementation of AEC. The study also attempts to find the initial design of strengthening the village UMKM that is adaptive to current regional and global trade liberalization. Field research will be conducted in Malang Regencies, Malang City, and Batu City, where all these areas have village UMKM that are

  9. Conference Report: International Research Symposium on Ankyloblepharon-Ectodermal Defects-Cleft Lip and/or Palate (AEC) Syndrome

    Science.gov (United States)

    Fete, Mary; vanBokhoven, Hans; Clements, Suzanne; McKeon, Frank; Roop, Dennis R.; Koster, Maranke I.; Missero, Caterina; Attardi, Laura D.; Lombillo, Vivian A.; Ratovitski, Edward; Julapalli, Meena; Ruths, Derek; Sybert, Virginia P.; Siegfried, Elaine C.; Bree, Alanna F.

    2009-01-01

    Ankyloblepharon-Ectodermal Defects-Cleft Lip/Palate (AEC) Syndrome (Hay-Wells syndrome, MIM #106220) is a rare autosomal dominant ectodermal dysplasia syndrome. It is due to mutations in the p63 gene, known to be a regulatory gene with many downstream gene targets. TP63 is important in the differentiation and proliferation of the epidermis, as well as many other processes including limb and facial development. It is also known that mutations in p63 lead to skin erosions. These erosions, especially on the scalp, are defining features of AEC syndrome and cause significant morbidity and mortality in these patients. It was this fact that led to the 2003 AEC Skin Erosion Workshop. That conference laid the groundwork for the International Research Symposium for AEC Syndrome held at Texas Children's Hospital in 2006. The conference brought together the largest cohort of individuals with AEC syndrome, along with a multitude of physicians and scientists. The overarching goals were to define the clinical and pathologic findings for improved diagnostic criteria, to obtain tissue samples for further study and to define future research directions. The symposium was successful in accomplishing these aims as detailed in this conference report. Following our report, we also present eleven manuscripts within this special section that outline the collective clinical, pathologic and mutational data from eighteen individuals enrolled in the concurrent Baylor College of Medicine IRB-approved protocol: Characterization of AEC syndrome. These collaborative findings will hopefully provide a stepping stone to future translational projects of p63 and p63-related syndromes. PMID:19353643

  10. Purposive Teaching Styles for Transdisciplinary AEC Education: A Diagnostic Learning Styles Questionnaire

    Directory of Open Access Journals (Sweden)

    Sharifah Mazlina Syed Khuzzan

    2015-07-01

    Full Text Available With the progressive globalisation trend within the Architecture, Engineering, and Construction (AEC industry, transdisciplinary education and training is widely acknowledged as being one of the key factors for leveraging AEC organisational success. Conventional education and training delivery approaches within AEC therefore need a paradigm shift in order to be able to address the emerging challenges of global practices. This study focuses on the use of Personalised Learning Environments (PLEs to specifically address learners’ needs and preferences (learning styles within managed Virtual Learning Environments (VLEs. This research posits that learners can learn better (and be more readily engaged in managed learning environments with a bespoke PLE, in which the deployment of teaching and learning material is augmented towards their individual needs. In this respect, there is an exigent need for the Higher Educational Institutions (HEIs to envelop these new approaches into their organisational learning strategy. However, part of this process requires decision-makers to fully understand the core nuances and interdependencies of functions and processes within the organisation, along with Critical Success Factors (CSFs and barriers. This paper presents findings from the development of a holistic conceptual Diagnostic Learning Styles Questionnaire (DLSQ Framework, comprised of six interrelated dependencies (i.e. Business Strategy, Pedagogy, Process, Resources, Systems Development, and Evaluation. These dependencies influence pedagogical effectiveness. These finding contribute additional understanding to the intrinsic nature of pedagogy in leveraging transdisciplinary AEC training within organisations (to improve learner effectiveness. This framework can help organisations augment and align their strategic priorities to learner-specific traits.

  11. Electronic equipment. New functional units in NIM standard

    International Nuclear Information System (INIS)

    Cheminaud, J.; Grasso, G.; Lacroix, C.; Le Baud, P.; Pichot, G.; Poirot, L.

    During the year 1974 some new modules have been developed: i) a tele-control for delay-time which utilizes a multiplexer-demultiplexer; ii) a fast pulse generator for light-emitting diodes which allows the test of devices using photomultipliers; iii) a plug-in-unit of variable shaper for fast pulses, with reset and zero dead time; iv) an amplifier with a 50MHz band-pass and an adjusting amplification from 0 to 10; v) a pocket generator delivering NIM pulses [fr

  12. [Analysis of Koch phenomenon of Mycobacterium tuberculosis-infected guinea pigs vaccinated with recombinant tuberculosis vaccine AEC/BC02].

    Science.gov (United States)

    Lu, J B; Cheng, B W; Deng, H Q; Su, C; Shen, X B; Du, W X; Yang, L; Wang, G Z; Xu, M

    2016-07-01

    To observe the Koch phenomenon of Mycobacterium tuberculosis(MTB)-infected guinea pigs after vaccinated with killed H37Ra bacteria or tuberculosis vaccine candidate AEC/BC02. Eighteen guinea pigs were challenged subcutaneously with 5.0×10(3) CFU MTB and after 40 days were divided into 3 groups (6 per group): NS group, AEC/BC02 group and H37Ra group, which were injected intramuscularly 3 times at 1 day interval with normal saline, AEC/BC02 vaccine and killed H37Ra bacteria respectively. Three weeks after the first vaccination, all guinea pigs were sacrificed to evaluate gross pathological scores for liver, spleen and lung, bacterial loads in lung and spleen, and lung inflammation. The gross pathological score in H37Ra group (48±26) was lower than that in NS group(62±15), but the difference was not significant (t=1.093, P=0.300). The AEC/BC02 group had a significantly lower gross pathological score (36±15) than NS group (t=2.980, P=0.014). No significant difference between H37Ra group and AEC/BC02 group was observed (t=1.009, P=0.337). The spleen bacterial load [(5.31±0.80) log10 CFU]in H37Ra group was slightly lower than that in NS group[(5.57±0.75) log10 CFU] but the difference was not significant (t=1.581, P=0.574). In AEC/BC02 group bacterial load in the spleen was (4.64±0.64) log10 CFU and significantly lower than NS group (t=2.306, P=0.044) and no significant difference between H37Ra group and AEC/BC02 group was observed (t=1.602, P=0.140). Meanwhile, the lung bacterial load in AEC/BC02 group was (3.71±1.01) log10 CFU and in H37Ra group was (3.82±1.25) log10 CFU. Compared to (4.15±0.69) log10 CFU in the NS group, no significant differences were found (t=0.881, P=0.399; t=0.566, P=0.584, respectively). For the lung inflammation, the inflamed areas in H37Ra group were significantly larger [(33.0±4.4%)] than those in both NS group [(14.8±8.4) %, t=4.719, P=0.001] and AEC/BC02 group [(14.8±8.4) %, t=3.616, P=0.005], and no significant differences were

  13. Private Islamic Higher Education in Asean Economic Community (AEC Era

    Directory of Open Access Journals (Sweden)

    Mulyawan Safwandy Nugraha

    2016-12-01

    Full Text Available This article explores the challenge faced by Indonesia in ASEAN Economic Community (AEC era. It is also revealed the Private Islamic Religion Institution (PTKIS strategic to play its role and function in generating human resource. The method used is qualitative in the form of literature study. The result shows that PTKIS are required to adapt and see the AEC as an opportunity to change. A private status should be used as an institutional capital to create and innovate freely, by maximally utilizing the available resources. The management of a reputable institution is seen to be a significant factor for reinforcement. Aspects of visionary leadership, qualified lecturers, a curriculum that is responsive to a change, and an adequate infrastructure become a strengthening point toward the management accountability of universities in creating graduates who are competitive, skillful and qualified.

  14. Research on the effect of the external magnetic field in the joule balance at NIM

    Science.gov (United States)

    Xu, Jinxin; You, Qiang; Li, Zhengkun; Bai, Yang; Lu, Yunfeng; Zhang, Zhonghua; He, Qing

    2018-06-01

    The first determination of the Planck constant with the second generation of the joule balance, NIM-2, was completed in 2017 with an uncertainty of 2.4  ×  10‑7. Due to the movement of the magnet during the measurement process, the effect of the external field is a critical problem in NIM-2. At present, the electromagnet system is used in NIM-2. By taking the average of the results with positive and negative exciting currents, the uncertainty from the external field is reduced to 1.7  ×  10‑7, which is still the largest source in the uncertainty budget as all the other items are less than 1  ×  10‑7. In the near future, a permanent magnet system will be applied in NIM-2 and the main field cannot be reversed. Although the coupling of the external magnetic field in the permanent magnet system is about 40 times less than that in the electromagnet system, further reduction of this effect is still required in the permanent magnet system. In this paper, the effect of the external field is analyzed in both an electromagnet system and a permanent magnet system based on simulations and experiments. Then, the methods of magnetic shielding and compensation coils are proposed and simulated in the permanent magnet system. The results show that it may be possible to reduce the uncertainty of the external field to less than 2  ×  10‑8 in the permanent magnet system by employing the two methods.

  15. Variations of thermospheric composition according to AE-C data and CTIP modelling

    Directory of Open Access Journals (Sweden)

    H. Rishbeth

    2004-01-01

    Full Text Available Data from the Atmospheric Explorer C satellite, taken at middle and low latitudes in 1975-1978, are used to study latitudinal and month-by-month variations of thermospheric composition. The parameter used is the "compositional Ρ-parameter", related to the neutral atomic oxygen/molecular nitrogen concentration ratio. The midlatitude data show strong winter maxima of the atomic/molecular ratio, which account for the "seasonal anomaly" of the ionospheric F2-layer. When the AE-C data are compared with the empirical MSIS model and the computational CTIP ionosphere-thermosphere model, broadly similar features are found, but the AE-C data give a more molecular thermosphere than do the models, especially CTIP. In particular, CTIP badly overestimates the winter/summer change of composition, more so in the south than in the north. The semiannual variations at the equator and in southern latitudes, shown by CTIP and MSIS, appear more weakly in the AE-C data. Magnetic activity produces a more molecular thermosphere at high latitudes, and at mid-latitudes in summer. Key words. Atmospheric composition and structure (thermosphere – composition and chemistry

  16. Variations of thermospheric composition according to AE-C data and CTIP modelling

    Directory of Open Access Journals (Sweden)

    H. Rishbeth

    2004-01-01

    Full Text Available Data from the Atmospheric Explorer C satellite, taken at middle and low latitudes in 1975-1978, are used to study latitudinal and month-by-month variations of thermospheric composition. The parameter used is the "compositional Ρ-parameter", related to the neutral atomic oxygen/molecular nitrogen concentration ratio. The midlatitude data show strong winter maxima of the atomic/molecular ratio, which account for the "seasonal anomaly" of the ionospheric F2-layer. When the AE-C data are compared with the empirical MSIS model and the computational CTIP ionosphere-thermosphere model, broadly similar features are found, but the AE-C data give a more molecular thermosphere than do the models, especially CTIP. In particular, CTIP badly overestimates the winter/summer change of composition, more so in the south than in the north. The semiannual variations at the equator and in southern latitudes, shown by CTIP and MSIS, appear more weakly in the AE-C data. Magnetic activity produces a more molecular thermosphere at high latitudes, and at mid-latitudes in summer.

    Key words. Atmospheric composition and structure (thermosphere – composition and chemistry

  17. Novel variant in the TP63 gene associated to ankyloblepharon-ectodermal dysplasia-cleft lip/palate (AEC) syndrome.

    Science.gov (United States)

    Gonzalez, Francisco; Loidi, Lourdes; Abalo-Lojo, Jose M

    2017-01-01

    Ankyloblepharon-ectodermal dysplasia-cleft lip/palate (AEC) syndrome is a disorder resulting from anomalous embryonic development of ectodermal tissues. There is evidence that AEC syndrome is caused by mutations in the TP63 gene, which encodes the p63 protein. This is an important regulatory protein involved in epidermal proliferation and differentiation. Genome sequencing was performed in DNA from peripheral blood leukocytes of a newborn with AEC syndrome and her parents. Variants were searched in all coding exons and intron-exon boundaries of the TP63 gene. A heterozygous missense variant (NM_003722.4:c.1063G>C (p.Asp355His) was found in the newborn patient. No variants were found in either of the parents. We identified a previously unreported variant in TP63 gene which seems to be involved in the somatic malformations found in the AEC syndrome. The absence of this variant in both parents suggests that the variant appeared de novo.

  18. First report of metronidazole resistant, nimD-positive, Bacteroides stercoris isolated from an abdominal abscess in a 70-year-old woman

    DEFF Research Database (Denmark)

    Otte, Erik; Nielsen, Hans Linde; Hasman, Henrik

    2017-01-01

    We here present the first case of a metronidazole resistant nimD positive Bacteroides stercoris. The isolate originated from a polymicrobial intra-abdominal abscess in a 70-year-old woman. The nimD gene was detected by use of whole-genome shotgun sequencing and the subsequent use of the ResFinder 2...

  19. NIM Realization of the Gallium Triple Point

    Science.gov (United States)

    Xiaoke, Yan; Ping, Qiu; Yuning, Duan; Yongmei, Qu

    2003-09-01

    In the last three years (1999 to 2001), the gallium triple-point cell has been successfully developed, and much corresponding research has been carried out at the National Institute of Metrology (NIM), Beijing, China. This paper presents the cell design, apparatus and procedure for realizing the gallium triple point, and presents studies on the different freezing methods. The reproducibility is 0.03 mK, and the expanded uncertainty of realization of the gallium triple point is evaluated to be 0.17 mK (p=0.99, k=2.9). Also, the reproducibility of the gallium triple point was compared with that of the triple point of water.

  20. The impact of the AEC mode of tube current on the dose at CT scans

    Energy Technology Data Exchange (ETDEWEB)

    Moon, Il Bong; Dong, Kyung Rae [Dept. of Radiological Technology, Gwangju Health University, Gwangju (Korea, Republic of); Kim, Kwang Cheol [Dept. of of Nuclear Engineering, Chosun University,Gwangju (Korea, Republic of)

    2016-11-15

    In this study, the automatic exposure control (AEC) modes of tube current (SIEMENSCare Dose 4D and GE AEC mode) that CT manufacturers are using was applied to neck, chest and abdomen in order to determine the difference in the respective dose parameters (CTDIvol, DLP and mSv) resulting from the dose reduction. Equipment in use at C university adopted Care Dose 4D of Siemens and AEC mode of General Electric (GE), and the x-ray exposure conditions were adjusted to be as identical as possible between the experiments. For the assessment of the dose reduction, the differences between the doses with and without the use of the tube current AEC mode by the respective manufacturer were measured for each body part including neck, chest and abdomen of a human phantom, Rando Phantom (Art-200x, Fluke Biomedical, USA). First, the assessment of SIEMENS-Care Dose 4D yielded the following results. At the neck, the automatic exposure control resulted in a 3.3% reduction in CTDIvol and DLP, and a 3% reduction in the effective dose, mSv, compared to manual exposure control. The automatic exposure control at the chest displayed the reduction in CTDIvol and DLP by 25.5%, and in the effective dose, mSv, by 25.4% compared to the manual exposure control. In case of abdomen, CTDIvol and DLP were shown to be reduced by 16%, and the effective dose (mSv) by 16.3% under the automatic exposure control compared to the manual exposure. Second, the assessment results of GE AEC mode are as follows. The automatic exposure control at the neck resulted in a 45.1% reduction in CTDIvol and DLP, and a 44.7% reduction in the effective dose (mSv) in comparison to the manual exposure control. At the chest, the automatic exposure control displayed a 47.6% reduction in CTDIvol and DLP, and a 47.5% reduction in the effective dose, mSv, compared to the manual exposure control. At the abdomen, it was shown that CTDIvol and DLP were reduced by 26.9%, and the effective dose (mSv) by 26.8% under the automatic

  1. The impact of the AEC mode of tube current on the dose at CT scans

    International Nuclear Information System (INIS)

    Moon, Il Bong; Dong, Kyung Rae; Kim, Kwang Cheol

    2016-01-01

    In this study, the automatic exposure control (AEC) modes of tube current (SIEMENSCare Dose 4D and GE AEC mode) that CT manufacturers are using was applied to neck, chest and abdomen in order to determine the difference in the respective dose parameters (CTDIvol, DLP and mSv) resulting from the dose reduction. Equipment in use at C university adopted Care Dose 4D of Siemens and AEC mode of General Electric (GE), and the x-ray exposure conditions were adjusted to be as identical as possible between the experiments. For the assessment of the dose reduction, the differences between the doses with and without the use of the tube current AEC mode by the respective manufacturer were measured for each body part including neck, chest and abdomen of a human phantom, Rando Phantom (Art-200x, Fluke Biomedical, USA). First, the assessment of SIEMENS-Care Dose 4D yielded the following results. At the neck, the automatic exposure control resulted in a 3.3% reduction in CTDIvol and DLP, and a 3% reduction in the effective dose, mSv, compared to manual exposure control. The automatic exposure control at the chest displayed the reduction in CTDIvol and DLP by 25.5%, and in the effective dose, mSv, by 25.4% compared to the manual exposure control. In case of abdomen, CTDIvol and DLP were shown to be reduced by 16%, and the effective dose (mSv) by 16.3% under the automatic exposure control compared to the manual exposure. Second, the assessment results of GE AEC mode are as follows. The automatic exposure control at the neck resulted in a 45.1% reduction in CTDIvol and DLP, and a 44.7% reduction in the effective dose (mSv) in comparison to the manual exposure control. At the chest, the automatic exposure control displayed a 47.6% reduction in CTDIvol and DLP, and a 47.5% reduction in the effective dose, mSv, compared to the manual exposure control. At the abdomen, it was shown that CTDIvol and DLP were reduced by 26.9%, and the effective dose (mSv) by 26.8% under the automatic

  2. Index to the AEC/ERDA/DOE Air Cleaning Conferences

    International Nuclear Information System (INIS)

    Burchsted, C.A.

    1980-01-01

    A comprehensive index to the papers in the second through sixteenth AEC/ERDA/DOE Nuclear Air Cleaning Conference is discussed. The index will be published in early 1981 and will be designated as Volume 3 of the proceeding of the sixteenth conference. The index has three parts, a straight numeric tabulation, an author index, and a key word in context (KWIC) index

  3. IMPROVING THE HARD SKILLS AND SOFT SKILLS OF MADRASAH TEACHERS FOR DEALING ASEAN ECONOMIC COMMUNITY (AEC)

    OpenAIRE

    Laely Mahmudah

    2016-01-01

    ASEAN Economic Community (AEC) has been started rolling. Market competition, industry, and skilled workers, especially in the field of education are becoming increasingly stringent. Madrasah teachers as the front liners in the education process should improve the quality of human resources. Hard skills and soft skills of madrasah teachers must be improved to deal with the Asean Economic Community (AEC). Hard skills are academic skills that include pedagogic competence and professional compete...

  4. Improving The Hard Skills And Soft Skills Of Madrasah Teachers For Dealing ASEAN Economic Community (Aec)

    OpenAIRE

    Mahmudah, Laely

    2016-01-01

    ASEAN Economic Community (AEC) has been started rolling. Market competition, industry, and skilled workers, especially in the field of education are becoming increasingly stringent. Madrasah teachers as the front liners in the education process should improve the quality of human resources. Hard skills and soft skills of madrasah teachers must be improved to deal with the Asean Economic Community (AEC). Hard skills are academic skills that include pedagogic competence and professional compete...

  5. An Early Danish Computer Game: The case of Nim, Piet Hein, and Regnecentralen

    DEFF Research Database (Denmark)

    Jørgensen, Anker Helms

    2009-01-01

    This paper reports on the development of Nimbi, which is an early computer game implemented at the Danish Computer Company Regnecentralen in 1962-63. Nimbi is a variant of the ancient game Nim. The paper traces the primary origins of the development of Nimbi. These include a mathematical analysis...

  6. Galileo's Last Fly-Bys of Io: NIMS Observations of Loki, Tupan, and Emakong Calderas

    Science.gov (United States)

    Lopes, Rosaly M. C.; Kamp, L. W.; Davies, A. G.; Smythe, W. D.; Carlson, R. W.; Doute, S.; McEwen, A.; Turtle, E. P.; Leader, F.; Mehlman, R.

    2002-01-01

    NIMS results from the 2001 Galileo fly-bys of Io will be presented, focusing on three calderas that may contain lava lakes. Preliminary results from the January 2002 Io fly-by will be presented. Additional information is contained in the original extended abstract.

  7. THE READINESS OF SMES IN BULUNGAN TO FACE ASEAN ECONOMIC COMMUNITY (AEC

    Directory of Open Access Journals (Sweden)

    Nurus Soimah

    2017-11-01

    Full Text Available ASEAN Economic Community (AEC is formed on the basis of an agreement in order to create a relationship of closer cooperation among ASEAN countries. The agreement covers four strategic, namely: (1 the achievement of a single market and a unified production base, (2 a competitive economic region, (3 equitable economic growth, and (4 integrated with the global economy. This research aimed to identify the readiness of SMEs Facing the ASEAN Economic Community (AEC, which will begin to be realized in December 2015. This research is a qualitative descriptive research. The researcher took a case study on SMEs in Bulungan Regency by selecting informants by using Purposive Sampling. 36 SMEs domiciled in Bulungan Regency were taken as the research subject. The data used in this research was a combination of primary data obtained in the field through interviews and secondary data adapted from various sources as a reference for research writing. Data analysis techniques used was data reduction and validity techniques using triangulation. The result of the research shows that the problem of SMEs in Bulungan Regency is the problem of the production process, capital, marketing, and permit. Further research results indicate that Bulungan Regency Government has been trying to encourage the development of the SMEs, but the implementation of government policy is not maximized. Based on the conditions and problems faced by SMEs in Bulungan Regency, it is not ready to face the AEC.

  8. Formerly utilized MED/AEC sites remedial action program. Radiological survey of the Harshaw Chemical Company, Cleveland, Ohio

    International Nuclear Information System (INIS)

    Wynveen, R.A.; Smith, W.H.; Sholeen, C.M.; Justus, A.L.; Flynn, K.F.

    1984-04-01

    During the MED/AEC era, the Harshaw Chemical Company processed large quantities of normal uranium to produce both oxide and fluoride compounds. This work was done under contract to MED and its successor, AEC. Records indicated that at the time the AEC contract was terminated, the facility was decontaminated by Harshaw and released from AEC control in 1960. However, a search of AEC records indicated that documentation was insufficient to determine whether the decontamination work was adequate by current guidelines. Hence, a radiological assessment of the site ws initiated in 1976. The entire grounds and all buildings were surveyed using surface survey instruments to detect surface contamination and radiation detectors to determine general radiation levels. Extensive surface contamination was found throughout the site. While the major contamination was found in Plant C, significant levels of contamination also were found in 16 other buildings and at 32 exterior locations. The contaminating material seemed to be normal uranium exclusively. Air samples were taken at numerous indoor locations throughout the site, but no elevated levels of radon were detected. This was as expected since normal uranium has been separated from radium and hence radon levels are very low. Several soil samples were taken from around the site. Analyses of these samples indicated extensive soil contamination, as well as suspected contamination of the river bed in the vicinity of the plant outfall. Scheduled subsurface investigation of the site, as well as of the river bed and sewer system, have not been conducted. Levels of contamination at this site are significantly above guidelines for release of the site for unrestricted use. 57 figures, 7 tables

  9. Primjena podvodne masaže zračnim mjehurićima kod oboljelih od multiple skleroze – opservacijska pilot-studija

    OpenAIRE

    RENDULIĆ SLIVAR, Senka; KRAML, Oto

    2010-01-01

    Podvodna masaža zračnim mjehurićima – biserna kupka, jedan je od oblika hidroterapije. Podatci iz nekih studija pokazuju da biserna kupka može dovesti do subjektivnog poboljšanja u aktivnostima svakodnevnog života. U radu je provedena usporedba primjene biserne kupke u bolesnika s multiplom sklerozom u specijalnoj bolnici za medicinsku rehabilitaciju i u kućnim uvjetima. U istraživanje je uključeno 15 ispitanika obaju spolova. Oni su prema uputama specijalista fizijatra tri tjedna svaki drugi...

  10. The Network Information Management System (NIMS) in the Deep Space Network

    Science.gov (United States)

    Wales, K. J.

    1983-01-01

    In an effort to better manage enormous amounts of administrative, engineering, and management data that is distributed worldwide, a study was conducted which identified the need for a network support system. The Network Information Management System (NIMS) will provide the Deep Space Network with the tools to provide an easily accessible source of valid information to support management activities and provide a more cost-effective method of acquiring, maintaining, and retrieval data.

  11. Development of calibration facility for radon and its progenies at NIM (China)

    International Nuclear Information System (INIS)

    Liang, J.C.; Liu, H.R.; Zhang, M.; Zheng, P.H.; Guo, Q.J.; Yang, Z.J.; Li, Z.S.; Zhang, L.

    2015-01-01

    Accurate measurement of radon and its progenies is the basis to control the radon dose and reduce the risk of lung cancer caused. The precise calibration of measuring instrument is an important part of the quality control of measurements of the concentration of radon and radon progenies. To establish Chinese national standards and realise reliable calibrations of measuring instrument for radon and its progenies, a radon chamber with regulation capability of environmental parameters, aerosol and radon concentrations was designed and constructed at National Institute of Metrology (NIM). The chamber has a total volume of ∼20 m 3 including an exposure volume of 12.44 m 3 . The radon concentration can be controlled from 12 Bq m -3 to the maximum of 232 kBq m -3 . The regulation range of temperature, relative humidity and aerosol are 0.66-44.39 deg. C, 16.4-95 %RH and 10 2 -10 6 cm -3 , respectively. The main advantages of the NIM radon chamber with respect to maintaining a stable concentration and equilibrium factor of radon progenies in a wide range through automatic regulation and control of radon and aerosol are described. (authors)

  12. Composition of rock core from hole AEC-8, New Mexico

    International Nuclear Information System (INIS)

    Rhoderick, J.E.; Buck, A.D.

    1981-12-01

    AEC-8 is a borehole about 5000 ft deep located within the Waste Isolation Pilot Plant (WIPP) site in southeastern New Mexico. About 28 ft of rock core from seven depth intervals in this hole was characterized by petrographic examination. This included logging, examination of the rock with a stereomicroscope, examination of thin sections with a polarizing microscope, and examination of each sample by x-ray diffraction

  13. List of unrestricted NIM publications issued from 1966 to 1979

    International Nuclear Information System (INIS)

    Glen, H.W.

    1979-01-01

    This publication lists the 714 unrestricted reports, 294 papers, 19 patents, and 5 other technical publications that were issued as publications of the National Institute for Metallurgy from 1966 (the year of its inception) to 1st April, 1979. For ease of reference, these publications are also classified under the research programmes that gave rise to them. Also included are details of the 2 periodicals issued by NIM and a list of the current miscellaneous publications of the Institute, which include the annual report, and brochures and leaflets of various kinds [af

  14. List of unrestricted NIM publications issued from 1966 to 1978

    International Nuclear Information System (INIS)

    Glen, H.W.

    1977-01-01

    This publication lists the 679 unrestricted reports, 263 papers, 19 patents, and 4 other technical publications that were issued as publications of the National Institute for Metallurgy from 1966 (the year of its inception) to 1st April, 1978. For ease of reference, these publications are also classified under the research programmes that gave rise to them. Also included are details of the 2 periodicals issued by NIM and a list of the current miscellaneous publications of the Institute, which include the annual report, and brochures and leaflets of various kinds [af

  15. LAW REFORM OF SMALL AND MEDIUM ENTREPRISES (SMEs AND EQUITABLE COOPERATIVE FOR COMPETITIVENESS IMPROVEMENT IN AEC ERA

    Directory of Open Access Journals (Sweden)

    Koesrianti Koesrianti

    2017-02-01

    Full Text Available Small Medium Entreprises (SMEs and Cooperative have not received a proper law protection in facing trade liberation of ASEAN Economic Community (AEC and economic globalized world. In 2015 AEC has been established that would bring a huge change in Southeast Asia regionS and definitely will have a wide impact to business people in Indonesia. SMEs and Cooperative contribute to more than 90 percent of total Indonesian national economy. However, they are weak on investment and information technology and management skill as well as competition law among ASEAN Member States. Economic policies do not give a sufficient protection to SMEs and Cooperative. This article tries to seek solutions for SMEs problems especially their legal structure in order to enhance their competitiveness. This article argues that the government can provide legal protection by reforming SMEs economic sectors similar to the AEC’s priority sectors by which the Indonesian’ SMEs would become world class corporate.  Keywords: Cooperative, AEC, legal reform, SMEs

  16. AEC Advisory Committee report emphasizes personnel exchanges

    International Nuclear Information System (INIS)

    Anon.

    1984-01-01

    The Advisory Committee on Cooperation with Developing Countries set up in August 1983 in the AEC has studied for about one year the actual situations of nuclear energy development and utilization in developing countries and their expections toward Japan and also problems in Japan in this connection. The Advisory Committee's report is summarized: significance of nuclear energy cooperation; status of nuclear energy energy utilizations in developing countries; status and problems in Japan's cooperation (technical cooperation through IAEA and technical cooperation by JAERI, JAIF, etc.); future prospects (areas of cooperation including the uses of radioisotopes and radiation and research reactors, nuclear power generation, etc. and tasks of the Government and the private sector in expanding the cooperation). (Mori, K.)

  17. Engineering evaluation of a formerly utilized MED/AEC site. Site A and Plot M, Palos Forest Preserve, Palos Park, Illinois

    International Nuclear Information System (INIS)

    1979-09-01

    This engineering evaluation report (EER) addresses one of these MED/AEC sites known as Site A/Plot M, located in Palos Park, Illinois. The EER describes in technical detail a number of options for remedial action that could be taken with respect to the contamination at Site A/Plot M and presents estimates of the costs associated with these options. A companion document, Environmental Analysis Report on a Formerly Utilized MED/AEC Site, Site A and Plot M, Palos Forest Preserve, Palos Park, Illinois (ANL/ES-79), has also been prepared. It describes in detail the existing site environment and evaluates the environmental impacts of the various remedial options discussed in this report. This EER contributes to a better understanding of the mitigation or resolution of environmental problems posed by the subject MED/AEC site and serves as a basis for determining whether or not remedial actions are warranted. The knowledge derived from the evaluation of a number of remedial options should be helpful in the final disposition of other MED/AEC sites located elsewhere

  18. PENGARUH RASIO CAR, NPL, LDR, BOPO, DAN NIM TERHADAP KINERJA BANK UMUM DI INDONESIA

    Directory of Open Access Journals (Sweden)

    Dwi Priyanto Agung Raharjo

    2015-10-01

    Full Text Available This research is performed on order to test the influence of the variable Capital Adequacy Ratio (CAR, Non Performing Loan (NPL, Loan to Deposit Ratio (LDR, BOPO (Operating Expenses / Operating Income, and Net Interest Margin (NIM, to return on Asset (ROA. The sample used in the study were 120 bank in Indonesia in 2010 and 2011. The data analysis technique used is multiple linear regression, t-statistic and F-statistics test with a significance level of 5%. During research period show as variable and data research was normal distributed. Based on test, multicolinearity, heterosscedasticity and autocorrelation classic assumption deviation has no founded, this indicate that the available data has fulfill the condition to use multi linear regression model. This result of research show that variable CAR, NIM, and LDR positive significant influence toward ROA. Variable NPL and BOPO negative significant influence toward ROA. Prediction capability from these seven variable toward ROA is 78,7 % where the balance 21,3% is affected to other factor which was not to be entered to research model.

  19. Assessment of patient dose reduction when using AEC technique in toshiba 64 MDCT

    International Nuclear Information System (INIS)

    Khojali, Wadah Mohamed Ali.

    2016-03-01

    The aim of research is to evaluate the efficiency of AEC (SUREDOSE) used in Toshiba CT scanner in reducing patient radiation dose. 107 patients were studied from four CT scanners. Scan factors and radiation dose received during abdominal CT scan was registered between the contract phases of abdominal CT scan, where the arterial contrast phases was done with Routine Manual Protocol i.e. fixed mA and kVp regardless patient age, weight and reason of scan, while the vinous phase done using AEC. The mA values were considerably less in vinous phase than in the arterial phase for all hospitals with exceptional to hospital 4 where the mA values had increased. There were no variations between the two phases in the other scan factors (kVp. pitch, slice thickness, scan length), which indicates that the software was mainly changing the mA values. The mA also showed wide variations during venous phase as a result of the varying mA applied by the AEC for the different patient ages and weights. The data collection has showed that, the application of SURDOSE decreases that average mA by 56.6%, 61%6 and 56.6 for hospitals 1, 2, and 3 respectively. The reduction of the average of the CTD1_vol were 54.2%. 64.1% in hospital 1.2. and 3 respectively. The average DLPs were also less by 57.1%. 62.8%. 57.5% in hospital, 2, and 3 respectively between the phases. In hospital 4 one raw of the CT detector was not functioning this has disturbed the SURDOSE software. Leading to increase of the mA values and hence the patient radiation dose mA, CTD1_vol and DLP in this hospital increased by 47.7%, 54.3% and 42.8% respectively. This highlighted the risk of not applying the AEC correctly. The non application of this software was only due to lake of knowledge how to use it and the benefits of dose reduction associated with it. Application of this software is very useful and operator should be trained to use it in all CT exams. (Author)

  20. Extrato aquoso de sementes de nim no controle de Liriomyza sativae (Diptera: Agromyzidae em meloeiro

    Directory of Open Access Journals (Sweden)

    Ewerton Marinho Costa

    2016-06-01

    Full Text Available RESUMO O controle da mosca minadora é imprescindível nas áreas de produção de melão dos estados do Rio Grande do Norte e Ceará. Portanto, o objetivo do trabalho foi avaliar o efeito de diferentes concentrações do extrato aquoso de sementes de nim (Azadirachta indica sobre a mosca minadora (Liriomyza sativae. O experimento foi conduzido em delineamento inteiramente casualizado, constituído por sete tratamentos: Testemunha absoluta (água destilada, testemunha positiva (inseticida Vertimec® 18 CE - Abamectina e cinco concentrações do extrato aquoso de sementes de nim (1; 5; 10; 15 e 20 g 100 mL-1 de água destilada, com 10 repetições (plantas de meloeiro. Os tratamentos foram aplicados via pulverização, com auxílio de um pulverizador manual. As avaliações foram divididas em duas etapas, na primeira, registrou-se a mortalidade larval e, na segunda, a mortalidade pupal, em cada um dos tratamentos. Foi verificado que houve aumento da mortalidade larval e pupal de L. sativaecom o aumento da concentração do extrato aquoso de sementes de nim. As concentrações de 15 e 20 g 100 mL-1 do extrato ocasionaram mortalidade larval de 91 e 91,8% com eficiência de controle de 89,7 e 90,6%, respectivamente. Todas as concentrações avaliadas ocasionaram significativa mortalidade pupal das larvas que sobreviveram, destacando-se as concentrações de 5; 10; 15 e 20 g 100 mL-1 com 99,4; 100; 100 e 100% de mortalidade, respectivamente.

  1. IMPROVING THE HARD SKILLS AND SOFT SKILLS OF MADRASAH TEACHERS FOR DEALING ASEAN ECONOMIC COMMUNITY (AEC

    Directory of Open Access Journals (Sweden)

    Laely Mahmudah

    2016-11-01

    Full Text Available ASEAN Economic Community (AEC has been started rolling. Market competition, industry, and skilled workers, especially in the field of education are becoming increasingly stringent. Madrasah teachers as the front liners in the education process should improve the quality of human resources. Hard skills and soft skills of madrasah teachers must be improved to deal with the Asean Economic Community (AEC. Hard skills are academic skills that include pedagogic competence and professional competence. How to improve the hard skills is to meet the pedagogic competence (ability to manage learning students and professional competence (the ability to master the learning material is broad and deep. Soft skills is the ability to organize themselves (intrapersonal skills, such as creativity, motivation, and self-contained and the ability to interact with others (interpersonal skills, such as communication, team building and adaptation to maximize performance. Soft skills include personal competence and social competence. Madrasah teachers should be able to change the mindset of a passenger became good driver. Professional madrasah teachers are teachers who have the balanced hard skills and soft skills, which can compete healthily in AEC era.

  2. Knowledge Management Practice in Two Australian Architecture-Engineering-Construction (AEC Companies

    Directory of Open Access Journals (Sweden)

    Patrick Zou

    2012-11-01

    Full Text Available Knowledge management (KM could be described as a management system that supports the creation, sharing and retrieving of valued information, expertise and insight within and across communities of people and related organizations using information and communication technologies and hence it is a combination of the effective application of information technlogy and management of human resources. KM is becoming a core competitive factor in construction operations. This paper presents the results of two case studies of KM practices in large AEC (architecture, engineering and construction companies through desk-top study and semi-structured interviews. The results indicate that implementing KM in AEC companies leads to competitive advantages and improved decision-making, problem solving and business performance. The results also indicateed that while technology plays an important role, top management commitment, total employee involvement, performance assessment and the culture of knowledge-learning and sharing must be considered when implementing KM. Therefore it is suggested that the implementation of KM should incorporate the company's vision, work processes, technology and culture, to improve the ability of knowledge creating, capturing, sharing, retrieving and ultimately, to improve the company's competitive advantage, decision making, problem solving and innovation.

  3. Dynamic Isotope Power System (DIPS) Applications Study. Volume II. Nuclear Integrated Multimission Spacecraft (NIMS) design definition. Final report

    International Nuclear Information System (INIS)

    1979-11-01

    The design requirements for the Nuclear Integrated Multimission Spacecraft. (NIMS) are discussed in detail. The requirements are a function of mission specifications, payload, control system requirements, electric system specifications, and cost limitations

  4. Design logistics performance measurement model of automotive component industry for srengthening competitiveness of dealing AEC 2015

    Science.gov (United States)

    Amran, T. G.; Janitra Yose, Mindy

    2018-03-01

    As the free trade Asean Economic Community (AEC) causes the tougher competition, it is important that Indonesia’s automotive industry have high competitiveness as well. A model of logistics performance measurement was designed as an evaluation tool for automotive component companies to improve their logistics performance in order to compete in AEC. The design of logistics performance measurement model was based on the Logistics Scorecard perspectives, divided into two stages: identifying the logistics business strategy to get the KPI and arranging the model. 23 KPI was obtained. The measurement result can be taken into consideration of determining policies to improve the performance logistics competitiveness.

  5. From Mars to Minerva: The origins of scientific computing in the AEC labs

    Energy Technology Data Exchange (ETDEWEB)

    Seidel, R.W. [ERA Land Grant Professor of the History of Technology]|[Charles Babbage Institute, University of Minnesota, Minneapolis, Minnesota (United States)

    1996-10-01

    Although the AEC laboratories are renowned for the development of nuclear weapons, their largess in promoting scientific computing also had a profound effect on scientific and technological development in the second half of the 20th century. {copyright} {ital 1996 American Institute of Physics.}

  6. Nuclear Instrumentation Module (NIM) standard logic processor as a portal signal analyzer

    International Nuclear Information System (INIS)

    Minges, G.P.

    1978-01-01

    A general purpose electronic logic processor has been designed into a 2 wide NIM (Nuclear Instrumentation Module) bin module. The unit utilizes a microprocessor to achieve necessary versatility. The processor's first use is as a new generation signal analyzer for use in radiometric personnel and vehicle portal monitors. Significant improvements have been obtained in sensitivity and stability over existing analog discriminators. The new analyzer is presently being used to update personnel and vehicle portal monitoring systems

  7. Composition and structure of fresh ammonia clouds on Jupiter based on quantitative analysis of Galileo/NIMS and New Horizons/LEISA spectra

    Science.gov (United States)

    Sromovsky, L. A.; Fry, P. M.

    2018-06-01

    Ammonia gas has long been assumed to be the main source of condensables for the upper cloud layer on Jupiter, but distinctive spectral features associated with ammonia have been seen only rarely. Since both ammonia and NH4SH absorb in the 3 μm region, and widespread absorption in the 3 μm region was present (Sromovsky and Fry, 2010), identification of the 2 μm absorption feature of NH3 provided an opportunity to clearly establish its presence in Jovian clouds. Baines et al. (2002) succeeded in finding in Near Infrared Mapping Spectrometer (NIMS) observations one feature that had both 2 μm and 3 μm absorption, and many which were known to have absorption at 2.73 μm. They named these Spectrally Identifiable Ammonia Clouds (SIACs). They also argued that these were fresh ammonia clouds that would eventually succumb to some process that would obscure their absorption features. Detection of many more of the 2 μm features was later achieved by New Horizon's Linear Etalon Imaging Spectral Array (LEISA) instrument, which provided both the spatial and spectral resolution needed to identify these features. Here we report on the first quantitative modeling that uses NIMS spectra over a broad (1-5.2 μm) spectral range and LEISA spectra over a much narrower (1.25-2.5 μm) spectral range to constrain the cloud structure and composition of these rare cloud features and compare them to background clouds. We find that the absorption signature at 2 μm, which is well characterized in LEISA spectra, is relatively subtle and easily matched by model clouds containing spherical particles of ammonia ice with radii of 2-4 μm. The NIMS spectra, which cover both reflected sunlight as well as thermal emission regions are more difficult to model with cloud materials plausibly present in Jupiter's atmosphere. The best signal/noise spectra obtained from NIMS provide a relatively sparse sampling of the spectrum, which does not establish the detailed shape of the 3 μm absorption region

  8. Jaume Gil, orguener valencià del temps del Magnànim.

    OpenAIRE

    Cortés Escrivà, Josepa

    1985-01-01

    Peripècia vital i professional de Jaume Gil (+València 1444), constructor d’orgues, que treballà en diverses ocasions per al rei Alfons el Magnànim fabricant alguns orgues destinats a la capella reial. S’inclou, així mateix, edició de l’inventari post mortem dels seus béns, entre ells alguns instruments musicals i vuit llibres de gramàtica, i les eines del seu ofici. Vital and professional vicissitudes of Jaume Gil (+Valencia 1444), organs builder, which worked on several occasions to King...

  9. 10 kVp rule – An anthropomorphic pelvis phantom imaging study using a CR system: Impact on image quality and effective dose using AEC and manual mode

    International Nuclear Information System (INIS)

    Lança, Luís; Franco, Loris; Ahmed, Abdulfatah; Harderwijk, Marloes; Marti, Chloe; Nasir, Sadeeda; Ndlovu, Junior; Oliveira, Miguel; Santiago, Ana Rita; Hogg, Peter

    2014-01-01

    Purpose: This study aims to investigate the influence of tube potential (kVp) variation in relation to perceptual image quality and effective dose (E) for pelvis using automatic exposure control (AEC) and non-AEC in a Computed Radiography (CR) system. Methods and materials: To determine the effects of using AEC and non-AEC by applying the 10 kVp rule in two experiments using an anthropomorphic pelvis phantom. Images were acquired using 10 kVp increments (60–120 kVp) for both experiments. The first experiment, based on seven AEC combinations, produced 49 images. The mean mAs from each kVp increment were used as a baseline for the second experiment producing 35 images. A total of 84 images were produced and a panel of 5 experienced observers participated for the image scoring using the two alternative forced choice (2AFC) visual grading software. PCXMC software was used to estimate E. Results: A decrease in perceptual image quality as the kVp increases was observed both in non-AEC and AEC experiments, however no significant statistical differences (p > 0.05) were found. Image quality scores from all observers at 10 kVp increments for all mAs values using non-AEC mode demonstrates a better score up to 90 kVp. E results show a statistically significant decrease (p = 0.000) on the 75th quartile from 0.37 mSv at 60 kVp to 0.13 mSv at 120 kVp when applying the 10 kVp rule in non-AEC mode. Conclusion: Using the 10 kVp rule, no significant reduction in perceptual image quality is observed when increasing kVp whilst a marked and significant E reduction is observed

  10. Image quality and dose analysis for a PA chest X-ray: Comparison between AEC mode acquisition and manual mode using the 10 kVp ‘rule’

    International Nuclear Information System (INIS)

    Reis, Cláudia; Gonçalves, João; Klompmaker, Corrie; Bárbara, Ana Rita; Bloor, Chloe; Hegarty, Ryan; Lagrange, Tania; Temming, Noëlle; Sønnesyn, Mathilde; Røkeness, Henriette; Yamasathien, Amandine; Hogg, Peter

    2014-01-01

    Purpose: To compare the image quality and effective dose applying the 10 kVp rule with manual mode acquisition and AEC mode in PA chest X-ray. Method: 68 images (with and without lesions) were acquired using an anthropomorphic chest phantom using a Wolverson Arcoma X-ray unit. These images were compared against a reference image using the 2 alternative forced choice (2AFC) method. The effective dose (E) was calculated using PCXMC software using the exposure parameters and the DAP. The exposure index (lgM provided by Agfa systems) was recorded. Results: Exposure time decreases more when applying the 10 kVp rule with manual mode (50%–28%) when compared with automatic mode (36%–23%). Statistical differences for E between several ionization chambers' combinations for AEC mode were found (p = 0.002). E is lower when using only the right AEC ionization chamber. Considering the image quality there are no statistical differences (p = 0.348) between the different ionization chambers' combinations for AEC mode for images with no lesions. Considering lgM values, it was demonstrated that they were higher when the AEC mode was used compared to the manual mode. It was also observed that lgM values obtained with AEC mode increased as kVp value went up. The image quality scores did not demonstrate statistical significant differences (p = 0.343) for the images with lesions comparing manual with AEC mode. Conclusion: In general the E is lower when manual mode is used. By using the right AEC ionising chamber under the lung the E will be the lowest in comparison to other ionising chambers. The use of the 10 kVp rule did not affect the visibility of the lesions or image quality

  11. The role of high speed photography in plasma instability research on the AEC tokamak

    International Nuclear Information System (INIS)

    Fletcher, J.D.; Coster, D.P.; De Villiers, J.A.M.; Kotze, P.B.; Nothnagel, G.; O'Mahony, J.R.; Roberts, D.E.; Sherwell, D.

    1986-01-01

    High speed cine photography is a useful diagnostic aid for studying plasma behaviour and plasma surface interactions in fusion research devices like tokamaks. Such a system has been installed on the AEC tokamak. This paper reports some preliminary results obtained during typical plasma discharges

  12. Características dendrométricas de um povoamento de nim indiano (Azadirachta indica A. Juss no semiárido paraibano

    Directory of Open Access Journals (Sweden)

    Francisco Tibério de Alencar Moreira

    2012-11-01

    Full Text Available O Nim (Azadirachia indica A. Juss é uma espécie de múltiplo uso que pertence a família Meliaceae. Por possuir múltiplos usos, o nim tem despertado a atenção e seus produtos têm sido cada vez mais utilizados na área de agricultura. No entanto, aspectos dendrométricos relacionados ao crescimento da espécie ainda são escassos. O presente trabalho teve como objetivo avaliar o crescimento da espécie nim plantada em região semiárida do Nordeste brasileiro em dois diferentes espaçamentos. A coleta de dados foi realizada em duas áreas localizadas na Fazenda Laranjeiras, localizada no município de São José de Espinharas, Estado da Paraíba. No plantio-1 o espaçamento usado foi de 5 m x 5 m semeado no ano de 1996, em uma área de 2100 m2 e no plantio-2 o espaçamento usado foi de 4 m x 4 m em 1998, em uma área de 1600 m2. As variáveis medidas foram: DNB-Diâmetro a 0,30 cm do nível do solo (cm, HF-Altura do fuste comercial (m, HT-Altura total (m e DC-Diâmetro de copa (m. A partir destes dados foram calculados o volume cilíndrico (m3/ha, volume real (m3/ha, volume empilhado (st/ha e a área basal (m2/ha. O crescimento do nim indiano na região semiárida paraibana apresentou comportamento semelhante ao de outras áreas experimentais estudadas. Quando se pretende produzir madeira com finalidade energética o espaçamento mais indicado, entre os dois avaliados, é o de menor espaçamento.

  13. SU-E-I-34: Evaluating Use of AEC to Lower Dose for Lung Cancer Screening CT Protocols

    International Nuclear Information System (INIS)

    Arbique, G; Anderson, J; Guild, J; Duan, X; Malguria, N; Omar, H; Brewington, C; Zhang, D

    2015-01-01

    Purpose: The National Lung Screening Trial mandated manual low dose CT technique factors, where up to a doubling of radiation output could be used over a regular to large patient size range. Recent guidance from the AAPM and ACR for lung cancer CT screening recommends radiation output adjustment for patient size either through AEC or a manual technique chart. This study evaluated the use of AEC for output control and dose reduction. Methods: The study was performed on a multidetector helical CT scanner (Aquillion ONE, Toshiba Medical) equipped with iterative reconstruction (ADIR-3D), AEC was adjusted with a standard deviation (SD) image quality noise index. The protocol SD parameter was incrementally increased to reduce patient population dose while image quality was evaluated by radiologist readers scoring the clinical utility of images on a Likert scale. Results: Plots of effective dose vs. body size (water cylinder diameter reported by the scanner) demonstrate monotonic increase in patient dose with increasing patient size. At the initial SD setting of 19 the average CTDIvol for a standard size patient was ∼ 2.0 mGy (1.2 mSv effective dose). This was reduced to ∼1.0 mGy (0.5 mSv) at an SD of 25 with no noticeable reduction in clinical utility of images as demonstrated by Likert scoring. Plots of effective patient diameter and BMI vs body size indicate that these metrics could also be used for manual technique charts. Conclusion: AEC offered consistent and reliable control of radiation output in this study. Dose for a standard size patient was reduced to one-third of the 3 mGy CTDIvol limit required for ACR accreditation of lung cancer CT screening. Gary Arbique: Research Grant, Toshiba America Medical Systems; Cecelia Brewington: Research Grant, Toshiba America Medical Systems; Di Zhang: Employee, Toshiba America Medical Systems

  14. Sexual dimorphic function of IL-17 in salivary gland dysfunction of the C57BL/6.NOD-Aec1Aec2 model of Sjögren's syndrome.

    Science.gov (United States)

    Voigt, Alexandria; Esfandiary, Lida; Wanchoo, Arun; Glenton, Patricia; Donate, Amy; Craft, William F; Craft, Serena L M; Nguyen, Cuong Q

    2016-12-13

    Interleukin (IL)-17 is one of the critical inflammatory cytokines that plays a direct role in development of Sjögren's syndrome (SjS), a systemic autoimmune disease characterized by a progressive chronic attack against the exocrine glands. The expression levels of IL-17 are correlated with a number of essential clinical parameters such as focus score and disease duration in human patients. Significantly immunological differences of Th17 cells were detected at the onset of clinical disease in female SjS mice compared to males. To further define the role of IL-17 in SjS and elucidate its involvement in the sexual dimorphism, we examined the systemic effect of IL-17 by genetically ablating Il-17 in the C57BL/6.NOD-Aec1Aec2, spontaneous SjS murine model. The results indicate that IL-17 is a potent inflammatory molecule in the induction of chemoattractants, cytokines, and glandular apoptosis in males and females. Elimination of IL-17 reduced sialadenitis more drastically in females than males. IL-17 is highly involved in modulating Th2 cytokines and altering autoantibody profiles which has a greater impact on changing plasma cells and germinal center B cell populations in females than males. The result supports a much more important role for IL-17 and demonstrates the sexual dimorphic function of IL-17 in SjS.

  15. Duhovnost kao resurs snage i otpornosti obitelji u rizičnim okolnostima

    OpenAIRE

    Leutar, Ivan; Leutar, Zdravka

    2017-01-01

    Duhovnost se može shvatiti kao ljudsku potrebu za pronalaženjem krajnjeg smisla i svrhe u životu te želju da se živi integriranim životom. Istraživanja su pokazala da religiozne obitelji, u odnosu na one koje to nisu, za vrijeme trajanja nesigurnosti, neizvjesnosti i stresa imaju veću razinu vjere i nade u dobar ishod, njihovi članovi rjeđe izražavaju određene sociopatološke pojave. Cilj je rada dobiti uvid kako sudionici doživljavaju duhovnost u suočavanju s rizičnim okolnostima u obitelji, ...

  16. Basic Data Report for Monitor Well AEC-7 (C-2742) Reconfiguration Activities

    International Nuclear Information System (INIS)

    2005-01-01

    The New Mexico Office of the State Engineer (OSE) permitted well AEC-7 as C-2742. This well has been part of the far-field monitoring network since 1974. The well was used to obtain water level elevations and hydraulic parameters from both the Bell Canyon Formation and the Culebra Member of the Rustler Formation. This basic data report provides a historical account of the well from the original installation to the current configuration.

  17. Electron and ion temperatures: a comparison of ground-based incoherent scatter and AE-C satellite measurements

    International Nuclear Information System (INIS)

    Benson, R.F.; Bauer, P.; Brace, L.H.; Carlson, H.C.; Hagen, J.; Hanson, W.B.; Hoegy, W.R.; Torr, M.R.; Wickwar, V.B.

    1977-01-01

    The Atmosphere Exploere-C satellite (AE-C) is uniquely suited for correlative studies with ground-based stations because its on-board propulsion system enables a desired ground station overflight condition to be maintained for a period of several weeks. It also provides the first low-altitude (below 260 km) comparison of satellite and incoherent scatter electron and ion temperatures. More than 40 comparisons of remote and in situ measurements were made by using data from AE-C and four incoherent scatter stations (Arecibo, Chatanika, Millstone Hill, and St. Santin). The results indicate very good agreement between satellite and ground measurements of the ion temperature, the average satellite retarding potential analyzer temperatures differing from the average incoherent scatter temperatures by -2% at St. Santin, +3% at Millstone Hill, and +2% at Arecibo. The electron temperatures also agree well, the average satellite temperatures exceeding the average incoherent scatter temperatures by 3% at St. Santin, 2% at Arecibo, and 11% at Millstone Hill. Several temperature comparisons were made between AE-C and Chatanika. In spite of the highly variable ionosphere often encountered at this high-latitude location, good agreement was obtained between the in situ and remote measurements of electron and ion temperatures. Longitudinal variations are found to be very important in the comparisons of electron temperature in some locations. The agreement between the electron temperatures is considerably better than that found in some earlier comparisons involving satellities at higher altitudes

  18. Family Ownership and the Entrenchment Effect on Intellectual Capital Utilization: A Study of High-Technology Companies in Indonesia Dealing with the ASEAN Economic Community (AEC

    Directory of Open Access Journals (Sweden)

    Bima Cinintya Pratama

    2017-08-01

    Full Text Available At the end of 2015, the Association of Southeast Asian Nations (ASEAN brought into being the ASEAN Economic Community (AEC. Due to the AEC, the firms in ASEAN should utilize their resources more effectively and efficiently, so that the firms can survive and grow despite strong competition in the AEC. Indonesia, as the country with the largest economy in the region, needs to address this issue so that companies in Indonesia can face the challenges resulting from the AEC. This study aimed to examine the positive relationship between the intellectual capital (IC and the financial performance of high-technology (high-tech companies that are listed on the Indonesia Stock Exchange, and also to examine whether the entrenchment effect of family ownership exists. This study was conducted from 2008 to 2014. The final sample used in this study consisted of 31 companies with a total of 144 observations. This study used a panel data regression model analysis. The results showed that, for a company, IC has a positive impact on financial performance. This result indicated that the efficient and effective use of their IC will help the firms to achieve higher financial performance, and will be useful for dealing with the AEC. There was no evidence that the entrenchment effect exists in the family ownership of high-tech companies in Indonesia and hampers the utilization of IC.

  19. Family Ownership and the Entrenchment Effect on Intellectual Capital Utilization: A Study of High-Technology Companies in Indonesia Dealing with the ASEAN Economic Community (AEC

    Directory of Open Access Journals (Sweden)

    Bima Cinintya Pratama

    2017-07-01

    Full Text Available At the end of 2015, the Association of Southeast Asian Nations (ASEAN brought into being the ASEAN Economic Community (AEC. Due to the AEC, the firms in ASEAN should utilize their resources more effectively and efficiently, so that the firms can survive and grow despite strong competition in the AEC. Indonesia, as the country with the largest economy in the region, needs to address this issue so that companies in Indonesia can face the challenges resulting from the AEC. This study aimed to examine the positive relationship between the intellectual capital (IC and the financial performance of high-technology (high-tech companies that are listed on the Indonesia Stock Exchange, and also to examine whether the entrenchment effect of family ownership exists. This study was conducted from 2008 to 2014. The final sample used in this study consisted of 31 companies with a total of 144 observations. This study used a panel data regression model analysis. The results showed that, for a company, IC has a positive impact on financial performance. This result indicated that the efficient and effective use of their IC will help the firms to achieve higher financial performance, and will be useful for dealing with the AEC. There was no evidence that the entrenchment effect exists in the family ownership of high-tech companies in Indonesia and hampers the utilization of IC.

  20. Efeito de produtos a base de óleo de nim em diferentes formulações no controle de Plutella xylostella (L.,1758) (Lepidoptera: Plutellidae), em couve

    OpenAIRE

    Mondego, Janaina Marques [UNESP

    2011-01-01

    Este trabalho teve por objetivo avaliar a eficiência de diferentes doses e formulações de óleo de nim, seu poder residual e a decomposição no armazenamento, visando o controle de Plutella xylostella (L.), em couve. Os experimentos foram conduzidos em laboratório, sob condições controlada de temperatura (25 ± 2°C) umidade relativa (70 ± 10%) e fotofase (12 horas). Foram utilizadas diferentes doses e formulações do produto a base de nim. As doses utilizadas para larvas de primeiro instar foram:...

  1. Annual report: AEC Institute for Life Sciences, 1986

    International Nuclear Information System (INIS)

    1987-08-01

    The AEC-Institute for life sciences research programme can be divided into four divisions: experimental nuclear medicine, radiobiology, radiopharmacy and hormone receptor studies. The experimental nuclear medicine division investigates and undertakes new developments in nuclear diagnostics with a view to clinical application, especially developments in dataprocessing techniques and radiopharmaceuticals. Physiological, biochemical and pharmacological problems are also investigated by using tracers and nuclear diagnostic techniques. The radiobiology division is concerned with the development of biochemical techniques for determining radiosensitivity amongst radiation workers as well as clinical-biochemical, diagnostic procedures for identifying exposure to ionizing types of radiation (X- or gamma radiation). The hormone receptor division is concerned with the study of the role of steroid hormone receptors, steroids and carcinogenes in the etiology of breast cancer. Research projects as well as completed and ongoing research are listed in this report

  2. New Style of Volcanic Eruption Activity Identified in Galileo NIMS data at Marduk Fluctus, Io

    Science.gov (United States)

    Davies, A. G.; Davies, R. L.; Veeder, G. J.; de Kleer, K.; De Pater, I.; Matson, D.

    2017-12-01

    Analysis of observations of Marduk Fluctus, Io, by the Galileo Near Infrared Mapping Spectrometer (NIMS) reveals a style of volcanic activity not previously seen on Io - a very short-duration, highly-changeable, powerful thermal event, similar to what might be expected from a strombolian-like explosion. Marduk Fluctus is a persistent active volcano characterised by ≈3600 km2 of silicate flows [1]. Between 1996 and 2001, NIMS obtained 44 observations of Marduk Fluctus at a wide variety of spatial and spectral resolutions. Six observations were obtained during Galileo orbit E4, with five nighttime observations obtained on 1996 Dec 19 in the space of less than three hours. Three of these observations were each separated by one minute. Compared to the previous observation obtained a few hours earlier, the first two of these three observations show an order of magnitude increase in spectral radiance (corrected for emission angle). Spectral radiance then dropped back to the background level one minute later. The emission angles for these five E4 observations are large (>70°), but even without the emission angle radiance correction the spike in activity is still a factor of five larger than the pre- and post-spike radiances. The NIMS spectrum of the central observation shows a shift in peak of thermal emission to short wavelengths characteristic of the exposure of a large area of incandescent lava. The rapid increase and decrease in activity suggests an equally rapid physical process, the most likely being a large strombolian explosion that generated small clasts that cooled rapidly. The presence of such events provide an additional volcanic process that can be imaged with the intent of determining lava composition from eruption temperature, an important constraint on internal composition and state. For this particular eruption type, eruption temperature can be constrained if non-saturated, multiple-wavelength IR observations are obtained simultaneously and with very

  3. SU-E-I-48: The Behavior of AEC in Scan Regions Outside the Localizer Radiograph FOV: An In Phantom Study of CT Systems From Four Vendors

    Energy Technology Data Exchange (ETDEWEB)

    Supanich, M [Rush University Medical Center, Chicago, IL (United States); Bevins, N [Henry Ford Health System, Detroit, MI (United States)

    2014-06-01

    Purpose: This review of scanners from 4 major manufacturers examines the clinical impact of performing CT scans that extend into areas of the body that were not acquired in the CT localizer radiograph. Methods: Anthropomorphic chest and abdomen phantoms were positioned together on the tables of CT scanners from 4 different vendors. All of the scanners offered an Automatic Exposure Control (AEC) option with both lateral and axial tube current modulation. A localizer radiograph was taken covering the entire extent of both phantoms and then the scanner's Chest-Abdomen-Pelvis (CAP) study was performed with the clinical AEC settings employed and the scan and reconstruction range extending from the superior portion of the chest phantom through the inferior portion of the abdomen phantom. A new study was then initiated with a localizer radiograph extending the length of the chest phantom (not covering the abdomen phantom). The same CAP protocol and AEC settings were then used to scan and reconstruct the entire length of both phantoms. Scan parameters at specific locations in the abdomen phantom from both studies were investigated using the information contained in the DICOM metadata of the reconstructed images. Results: The AEC systems on all scanners utilized different tube current settings in the abdomen phantom for the scan completed without the full localizer radiograph. The AEC system behavior was also scanner dependent with the default manual tube current, the maximum tube current and the tube current at the last known position observed as outcomes. Conclusion: The behavior of the AEC systems of CT scanners in regions not covered by the localizer radiograph is vendor dependent. To ensure optimal image quality and radiation exposure it is important to include the entire planned scan region in the localizer radiograph.

  4. SU-E-I-48: The Behavior of AEC in Scan Regions Outside the Localizer Radiograph FOV: An In Phantom Study of CT Systems From Four Vendors

    International Nuclear Information System (INIS)

    Supanich, M; Bevins, N

    2014-01-01

    Purpose: This review of scanners from 4 major manufacturers examines the clinical impact of performing CT scans that extend into areas of the body that were not acquired in the CT localizer radiograph. Methods: Anthropomorphic chest and abdomen phantoms were positioned together on the tables of CT scanners from 4 different vendors. All of the scanners offered an Automatic Exposure Control (AEC) option with both lateral and axial tube current modulation. A localizer radiograph was taken covering the entire extent of both phantoms and then the scanner's Chest-Abdomen-Pelvis (CAP) study was performed with the clinical AEC settings employed and the scan and reconstruction range extending from the superior portion of the chest phantom through the inferior portion of the abdomen phantom. A new study was then initiated with a localizer radiograph extending the length of the chest phantom (not covering the abdomen phantom). The same CAP protocol and AEC settings were then used to scan and reconstruct the entire length of both phantoms. Scan parameters at specific locations in the abdomen phantom from both studies were investigated using the information contained in the DICOM metadata of the reconstructed images. Results: The AEC systems on all scanners utilized different tube current settings in the abdomen phantom for the scan completed without the full localizer radiograph. The AEC system behavior was also scanner dependent with the default manual tube current, the maximum tube current and the tube current at the last known position observed as outcomes. Conclusion: The behavior of the AEC systems of CT scanners in regions not covered by the localizer radiograph is vendor dependent. To ensure optimal image quality and radiation exposure it is important to include the entire planned scan region in the localizer radiograph

  5. Implementation of the National Incident Management System (NIMS)/Incident Command System (ICS) in the Federal Radiological Monitoring and Assessment Center(FRMAC) - Emergency Phase

    International Nuclear Information System (INIS)

    NSTec Environmental Restoration

    2007-01-01

    Homeland Security Presidential Directive HSPD-5 requires all federal departments and agencies to adopt a National Incident Management System (NIMS)/Incident Command System (ICS) and use it in their individual domestic incident management and emergency prevention, preparedness, response, recovery, and mitigation programs and activities, as well as in support of those actions taken to assist state and local entities. This system provides a consistent nationwide template to enable federal, state, local, and tribal governments, private-sector, and nongovernmental organizations to work together effectively and efficiently to prepare for, prevent, respond to, and recover from domestic incidents, regardless of cause, size, or complexity, including acts of catastrophic terrorism. This document identifies the operational concepts of the Federal Radiological Monitoring and Assessment Center's (FRMAC) implementation of the NIMS/ICS response structure under the National Response Plan (NRP). The construct identified here defines the basic response template to be tailored to the incident-specific response requirements. FRMAC's mission to facilitate interagency environmental data management, monitoring, sampling, analysis, and assessment and link this information to the planning and decision staff clearly places the FRMAC in the Planning Section. FRMAC is not a mitigating resource for radiological contamination but is present to conduct radiological impact assessment for public dose avoidance. Field monitoring is a fact-finding mission to support this effort directly. Decisions based on the assessed data will drive public protection and operational requirements. This organizational structure under NIMS is focused by the mission responsibilities and interface requirements following the premise to provide emergency responders with a flexible yet standardized structure for incident response activities. The coordination responsibilities outlined in the NRP are based on the NIMS

  6. Designing a power supply for Nim-bin formatted equipment; Diseno de una fuente de alimentacion para equipos con formato Nim-bin

    Energy Technology Data Exchange (ETDEWEB)

    Banuelos G, L. E.; Hernandez D, V. M.; Vega C, H. R., E-mail: lebluis2012@hotmail.com [Universidad Autonoma de Zacatecas, Unidad Academica de Estudios Nucleares, Cipres No. 10, Fracc. La Penuela, 98060 Zacatecas, Zac. (Mexico)

    2016-09-15

    From an old Nuclear Chicago power supply that was practically in the trash, was able to recover the 19 inches casing, rear connectors and the housing where the circuits were. From here all mechanical parts were cleaned and the electronic design was started to replace the original voltage and current functions of this equipment. The cards for the ±6, ±12 and ±24 voltages were designed, simulated and tested with circuitry that does not rely on specialized components or that is sold only by the equipment manufacturer. In the handling of the current by each voltage to operate, was possible to tie with the specifications of the manufacturers like Ortec or Canberra where a model of power supply gives a power of 160 Watts. Basic tests were performed to show that the behavior is very similar to commercial equipment; such as the full load regulation index and the noise level in the supply voltages. So our Nim-bin voltage source is viable for use in our institution laboratories. (Author)

  7. The Role of English Debating Tournament in the Face of the ASEAN Economy Community (AEC)

    Science.gov (United States)

    Husnawadi; Syamsudarni

    2016-01-01

    Since its establishment in the late 2015, the ASEAN Economic Community (AEC) with English as the official language has forced its participating countries to improve the quality of English language teaching, in the hope to prepare their people to be globally competitive, as the lack of English proficiency remains the main challenge across the…

  8. A/E/C Graphics Standard: Release 2.0 (formerly titled CAD Drafting Standard)

    Science.gov (United States)

    2015-08-01

    acronyms: • A/E/C – Architecture , Engineering, and Construction • BIM – Building Information Modeling • CAD – Computer-Aided Design • CIM – Civil...title GENERAL NOTES. General notes applicable to sheets for a particular discipline (e.g., architectural , electrical, mechanical) shall be located on...Filled fonts are used primarily for titles and on cover sheets. • Symbol font: This font should be used in cases where Greek symbols are

  9. Toxicity of neem oil to Bemisia tabaci biotype B nymphs reared on dry bean Toxicidade de óleo de nim para ninfas de Bemisia tabaci biótipo B criadas em feijoeiro

    Directory of Open Access Journals (Sweden)

    Patricia Valle Pinheiro

    2009-04-01

    Full Text Available The objective of this work was to determine the most susceptible nymphal stage of Bemisia tabaci biotype B to neem (Azadirachta indica A. Juss. oil applied to dry bean (Phaseolus vulgaris L. in a screenhouse. A solution of commercial oil (Dalneem extracted from neem seeds was sprayed directly on each nymphal instar at 0, 0.1, 0.25, 0.5, 1 and 2% concentrations for lethal concentration (LC determination, and at 0, 0.5 and 1% concentrations for lethal time (LT determination. The number of living and dead nymphs was recorded five days after spraying for LC determination, and daily during six days for LT determination. The LC50 estimated for fourth instar nymphs occurred at 0.56% concentration. For all instars, LC50 and LC95 were estimated at 0.32 and 2.78% concentrations, respectively. The estimated values of LT50 at 1% concentration were 2.46, 4.45, 3.02 and 6.98 days for the first to fourth instars, respectively. The LT50 occurred at five days for 0.5% and at four days for 1% concentration in all instars. A mortality rate of over 80% was observed on the 6th day for the first to third instars at 1% concentration. The first three nymphal stages were more susceptible to neem oil when compared to the fourth nymphal stage.O objetivo deste trabalho foi determinar o estágio ninfal de Bemisia tabaci biótipo B mais suscetível ao óleo de nim (Azadirachta indica A. Juss. aplicado em feijoeiro (Phaseolus vulgaris L., em casa telada. Foram avaliados o tempo letal (TL e concentração letal (CL do óleo comercial de sementes de nim Dalneem. Para CL, concentrações de 0, 0,1, 0,25, 0,5, 1 e 2% do produto foram pulverizadas diretamente sobre as ninfas em cada ínstar. Para TL, o produto foi avaliado a 0, 0,5 e 1% de óleo de nim em cada ínstar. Ninfas vivas e mortas foram contadas cinco dias após a pulverização para CL e diariamente para TL durante seis dias. Para o quarto ínstar, a CL50 foi de 0,56% de óleo de nim. Considerando todos os ínstares, CL

  10. AEC sets basic policy line on treatment and disposal of radioactive waste

    International Nuclear Information System (INIS)

    Anon.

    1976-01-01

    The AEC's new policy line for the treatment and disposal of radioactive wastes is explained with three tables added. The first table was prepared by MITI's Nuclear Fuel Advisory Committee regarding the projections on the amounts of radioactive wastes to be discharged from nuclear power plants, fuel fabrication plants and reprocessing plants, and the other two tables were made by the AEC committee on technical development of radioactive waste management, the one proposed the developmental steps necessary for establishing waste management technologies, and the other showed the related research and development items with target time schedule. The proper treatment and disposal of radioactive waste S are the problems that have to be resolved prior to the full development and utilization of nuclear energy. The Atomic Energy Commission set up a committee on July 29, 1975, to discuss the technologies on the management of radioactive wastes. The principle essential to the radioactive waste management was set, and it is desirable that this principle is put into practice with the cooperation and understanding of the people and all parties concerned. The countermeasures proposed will be subject to review yet as the technology makes further progress and they are as follows: on the high level radioactive waste management and the low-and intermediate-level radioactive waste management, the basic idea, targets and measures are given, and the methods for promoting experimental ocean dumping of low level radioactive wastes are proposed. (Iwakiri, K.)

  11. Designing a power supply for Nim-bin formatted equipment

    International Nuclear Information System (INIS)

    Banuelos G, L. E.; Hernandez D, V. M.; Vega C, H. R.

    2016-09-01

    From an old Nuclear Chicago power supply that was practically in the trash, was able to recover the 19 inches casing, rear connectors and the housing where the circuits were. From here all mechanical parts were cleaned and the electronic design was started to replace the original voltage and current functions of this equipment. The cards for the ±6, ±12 and ±24 voltages were designed, simulated and tested with circuitry that does not rely on specialized components or that is sold only by the equipment manufacturer. In the handling of the current by each voltage to operate, was possible to tie with the specifications of the manufacturers like Ortec or Canberra where a model of power supply gives a power of 160 Watts. Basic tests were performed to show that the behavior is very similar to commercial equipment; such as the full load regulation index and the noise level in the supply voltages. So our Nim-bin voltage source is viable for use in our institution laboratories. (Author)

  12. Feasibility study on an integrated AEC-grid device for the optimization of image quality and exposure dose in mammography

    Science.gov (United States)

    Kim, Kyo-Tae; Yun, Ryang-Young; Han, Moo-Jae; Heo, Ye-Ji; Song, Yong-Keun; Heo, Sung-Wook; Oh, Kyeong-Min; Park, Sung-Kwang

    2017-10-01

    Currently, in the radiation diagnosis field, mammography is used for the early detection of breast cancer. In addition, studies are being conducted on a grid to produce high-quality images. Although the grid ratio of the grid, which affects the scattering removal rate, must be increased to improve image quality, it increases the total exposure dose. While the use of automatic exposure control is recommended to minimize this problem, existing mammography equipment, unlike general radiography equipment, is mounted on the back of a detector. Therefore, the device is greatly affected by the detector and supporting device, and it is difficult to control the exposure dose. Accordingly, in this research, an integrated AEC-grid device that simultaneously performs AEC and grid functions was used to minimize the unnecessary exposure dose while removing scattering, thereby realizing superior image quality.

  13. Agribusiness entrepreneurship development strategy in East Java for welcoming ASEAN Economic Community (AEC era

    Directory of Open Access Journals (Sweden)

    Dewie Tri Wijayati

    2016-07-01

    Full Text Available Facing the implementation of ASEAN Economic Community (AEC at the end of 2015 requires strategic measures to make Indonesia ready to compete with other nations in ASEAN. East Java Province has great potentials and contributions in the national agribusiness. Establishing agribusiness in East Java towards increased competitiveness is the right step to welcome AEC 2015. This research attempts to study the appropriate model of agribusiness development strategy for East Java. The selection of strategy model is expected to prepare a strong and competitive economy in East Java. Through three principles of data analysis model of Miles and Huberman with the emphasis on data collection, data display, and verification, this study also used a variety of data collection techniques and verifications such as Focus Group Discussion (FGD, observation, and others. This research was conducted in four regions as the focus of the study area: Probolinggo District, Sidoarjo District, Pasuruan District and the City of Batu. The results provide the following conclusions: (a the agribusiness development strategy in East Java should be done with the target approach. This means that the introduction to the target is the most important factors to determine the strategy to be implemented; (b the role of the government is highly important and strategic in developing agribusiness in East Java. These can be implemented through a variety of program models that are tailored to the target.

  14. A report of the overall working group of the AEC Committee on Development of Advanced Power Reactors

    International Nuclear Information System (INIS)

    1979-01-01

    The AEC Committee on Development of Advanced Power Reactors was set up in April, 1978, following on the previous AEC Special Committee on Development of Advanced Power Reactors, in order to study on the complementary power reactors between current LWRs and future FBRs. The subjects of study by the overall working group are the status of advanced power reactors in views of the nuclear fuel cycle, the impacts on industries, the selection of reactor types under present international circumstances, and the evaluation of advanced power reactors in their technology and economy. The following matters are described: evaluations in view of the nuclear fuel cycle, i.e. the features of the ATR of Japan and CANDU reactors of Canada; international problems concerning nuclear nonproliferation and securing of uranium; problems in the diversification of power reactor types concerning the expenditure and technology; problems of technology in the ATR of Japan, CANDU reactors of Canada and Pu utilization for LWRs; and the economy of D 2 O power reactors, i.e. the ATR of Japan and CANDU reactors of Canada. (J.P.N.)

  15. Bioatividade de nanoformulações de nim sobre a traça-do-tomateiro Bioactivity of neem nanoformulations on tomato pinworm

    Directory of Open Access Journals (Sweden)

    Fátima Teresinha Rampelotti Ferreira

    2012-08-01

    Full Text Available O uso de plantas inseticidas é uma importante ferramenta para o manejo de insetos-praga. Visando ao controle de Tuta absoluta (Meyrick (Lepidoptera: Gelechiidae, nanoformulações de nim foram avaliadas. Após a estimativa de uma CL50 para uma formulação de óleo comercial de nim, bioensaios de seleção foram realizados com 22 nanoformulações. Para isso, lagartas neonatas foram alimentadas sobre folíolos tratados com soluções das nanoformulações durante 10 dias. Com as duas nanoformulações mais promissoras, NC40 aquoso e NC40 pó (NC 40=nanocápsulas de Poli- β-hidroxibutirato, foi avaliado o efeito sobre o desenvolvimento e a longevidade do inseto. A CL50 para o óleo de nim foi estimada em 0,20% ou 1,31mgL-1 de azadiractina. As nanoformulações NC40 aquoso e NC40 pó afetaram o desenvolvimento do inseto.The use of insecticide plants is an important tool in the management of insect pests. Aiming to control Tuta absoluta (Meyrick (Lepidoptera: Gelechiidae, neem nanoformulations were evaluated. After estimating the LC50 for a commercial neem oil formulation, selection bioassays were performed with 22 nanoformulations. In order to do that, newly emerged caterpillars were fed on leaflets treated with nanoformulation solutions for 10 days. The effect on the development and longevity of the insect was evaluated with the two most promising nanoformulations, aqueous NC40 and powdered NC40 (NC 40 = Poly-β-hydroxibutirate nanocapsules. The LC50 for neem oil was estimated in 0.20% or 1.31mgL-1 of azadiractin. The nanoformulations aqueous NC40 and powdered NC40 affected the insect development.

  16. A Tale of Two Hot Spots: Charting Thermal Output Variations at Prometheus and Amirani from Galileo NIMS Data

    Science.gov (United States)

    Davies, A. G.

    2002-12-01

    Galileo Near Infrared Mapping Spectrometer (NIMS) data show that the active ionian volcanoes Prometheus and Amirani have significant thermal emission in excess of non-volcanic background emission in every geometrically appropriate NIMS observation. The 5 μm brightness of these volcanoes shows considerable variation from orbit to orbit. Like the flank eruptions on Kilauea, Hawai'i, which began in 1983, these ionian volcanoes exhibit periods of elevated activity. A study of the 5 μm thermal emission in all low-spatial resolution NIMS observations (both night and day-time) from June 1996 (Orbit G1) to May 2001 (Orbit C30) shows that the Prometheus thermal output (uncorrected for emission angle, e) ranges from 4 to 21 GW/μm, and Amirani shows greater variations, from 4 to 31 GW/μm. Correcting all thermal outputs for observations where estandard deviation of 7.3 GW/μm) and a larger average Amirani thermal output of 44 GW/μm (standard deviation of 26 GW/μm). Prometheus showed its greatest e-corrected thermal emission during November 1997 (33 GW/μm), more than four times that seen in June 1996 (orbit G1; see Davies et al., 2000, Icarus, 148, 212-225) and Amirani showed its greatest thermal emission during May 1997 (orbit G8), nearly 100 GW/μm, nearly five times that seen during orbit G1. Prometheus and Amirani spectra obtained at night show that the overall spectral shape of the thermal emission from 2 to 5 μm does not greatly change. The style of eruption is not resulting in disproportionately large areas at very high temperatures in relation to cooler crustal areas, such as seen at Pillan in 1997 and at Pele, indicating that the style of eruption is not changing, just the areal extent of activity. Scaling magma eruption rates derived from G1 NIMS data yields maximum and average volumetric eruption rates of 337 and 154 m3 s-1 for Amirani, and 128 and 52 m3 s-1 for Prometheus. The style and behavior of eruptions at Prometheus and Amirani are apparently very like

  17. Prepare SME in Facing AEC 2015 through English Training Program to Obtain the Export Market

    Directory of Open Access Journals (Sweden)

    Rianto Nurcahyo

    2015-09-01

    or the effect of two nominal variables and to measure the relation strength of each variable with other nominal variable (C as the coefficient of contingency. From the chi square method, difference from the SME before and after the Export English course training is expected to be found. The training will use classroom method. The title of this study is prepare SME in Facing AEC 2015 through English training program to obtain the export market.

  18. Balneoterapija/hidroterapija u bolesnika s reumatoidnim artritisom, ankilozantnim spondilitisom i psorijatičnim artritisom – deskriptivni pregled

    OpenAIRE

    GRAZIO, Simeon; DOKO, Ines

    2014-01-01

    Balneoterapija/hidroterapija neizostavni je dio rehabilitacije bolesnika s upalnim reumatskim bolestima. Kako se njena učinkovitost često dovodi u pitanje, cilj ovog rada je bio pretražiti literaturu koja govori o učinkovitosti balneoterapije/hidroterapije kod reumatoidnog artritisa, ankilozantnog spondilitisa i psorijatičnog artritisa. Računalnim putem pretražene su najpoznatije baze stručnih časopisa iz područja biomedicine (PubMed, Scopus, Ovid) u razdoblju od 1993. do 2013. s ključnim rij...

  19. Feasibility study of the correlation of lifetime health and mortality experience of AEC and AEC Contractor employees with occupational radiation exposure. Progress report No. 3, June 1, 1966-May 31, 1967

    Energy Technology Data Exchange (ETDEWEB)

    Mancuso, T.F.; Sanders, B.S.; Brodsky, A.

    1967-01-01

    The objective of this 5-year project is to assess the feasibility of using personnel, employment, medical, and radiation records in establishing the relationships between mortality patterns and levels of radiation exposure. The following AEC Contractor facilities were selected for the test runs: the three Oak Ridge facilities, Hanford, and several small feed materials plants. During this project year, the recording of personal data on Oak Ridge employees and feed materials centers will be intensified, other phases of the project will be continued, and the searching for deaths through the Social Security Administration will begin. (PCS)

  20. NIM: A Node Influence Based Method for Cancer Classification

    Directory of Open Access Journals (Sweden)

    Yiwen Wang

    2014-01-01

    Full Text Available The classification of different cancer types owns great significance in the medical field. However, the great majority of existing cancer classification methods are clinical-based and have relatively weak diagnostic ability. With the rapid development of gene expression technology, it is able to classify different kinds of cancers using DNA microarray. Our main idea is to confront the problem of cancer classification using gene expression data from a graph-based view. Based on a new node influence model we proposed, this paper presents a novel high accuracy method for cancer classification, which is composed of four parts: the first is to calculate the similarity matrix of all samples, the second is to compute the node influence of training samples, the third is to obtain the similarity between every test sample and each class using weighted sum of node influence and similarity matrix, and the last is to classify each test sample based on its similarity between every class. The data sets used in our experiments are breast cancer, central nervous system, colon tumor, prostate cancer, acute lymphoblastic leukemia, and lung cancer. experimental results showed that our node influence based method (NIM is more efficient and robust than the support vector machine, K-nearest neighbor, C4.5, naive Bayes, and CART.

  1. AEC sets five year nuclear safety research program

    International Nuclear Information System (INIS)

    Anon.

    1976-01-01

    The research by the government for the establishment of means of judging the adequacy of safety measures incorporated in nuclear facilities, including setting safety standards and collecting documents of general criteria, and the research by the industry on safety measures and the promotion of safety-related technique are stated in the five year program for 1976-80 reported by subcommittees, Atomic Energy Commission (AEC). Four considerations on the research items incorporated in the program are 1) technical programs relating to the safety of nuclear facilities and the necessary criteria, 2) priority of the relevant items decided according to their impact on circumstances, urgency, the defence-indepth concept and so on, 3) consideration of all relevant data and documents collected, and research subjects necessary to quantify safety measurement, and 4) consideration of technological actualization, the capability of each research body, the budget and the time schedule. In addition, seven major themes decided on the basis of these points are 1) reactivity-initiated accident, 2) LOCA, 3) fuel behavior, 4) structural safety, 5) radioactive release, 6) statistical method of safety evaluation, and 7) seismic characteristics. The committee has deliberated the appropriate division of researches between the government and the industry. A set of tables showing the nuclear safety research plan for 1976-80 are attached. (Iwakiri, K.)

  2. Formerly utilized MED/AEC sites remedial action program. Radiological survey of The George Herbert Jones Chemical Laboratory, The University of Chicago, Chicago, Illinois, June 13-17, 1977

    International Nuclear Information System (INIS)

    Wynveen, R.A.; Smith, W.H.; Mayes, C.B.; Justus, A.L.

    1982-05-01

    A comprehensive radiological survey was conducted at George Herbert Jones Chemical Laboratory at the University of Chicago, Chicago, Illinois. Radiochemistry for the MED/AEC project was performed in this building in the 1940s. The building is now used as laboratories, offices, and classrooms. The survey was undertaken to determine the location and quantities of any radioactive materials remaining from the MED/AEC operations. Forty-three spots of contamination possibly resulting from MED/AEC occupancy in 17 rooms exceeded the allowable limits as given in the ANSI Standard N13.12. Under current use conditions, the potential for radiation exposure to occupants of this building from these sources of contamination is remote. Concentrations of radon daughters in the air of the building, as measured with grab-sampling techniques, were below the limit of 0.01 WL above background as given in the Surgeon General's Guidelines. No long-lived radionuclides were detected in any air sample. Concentrations of radionuclides in soil samples from near the laboratory generally indicated background levels. In order to reduce the potential for radiation exposure, remedial measures such as stabilization of the contamination in place would be applicable as a short-term measure. In order to reduce the risk in the event that building modifications take place in the future, health physics procedures and coverage are recommended. The long-term solution would involve decontamination by removal of the radioactive residues from the 17 rooms or areas where contamination possibly resulting from MED/AEC activities was detected

  3. Atividade de extrato aquoso de folhas de nim (Azadirachta indica sobre Spodoptera frugiperda Activity of neem tree (Azadirachta indica leaves aqueous extract on Spodoptera frugiperda

    Directory of Open Access Journals (Sweden)

    Hélio Teixeira Prates

    2003-03-01

    Full Text Available A lagarta-do-cartucho do milho (Spodoptera frugiperda (J. E. Smith tem sido controlada com inseticidas sintéticos. Uma das caracteristicas do nim (Azadirachta indica A. Juss é sua atividade inseticida contra pragas, como sucedâneo aos sintéticos. O objetivo deste trabalho foi avaliar a atividade inseticida do extrato aquoso das folhas do nim sobre a lagarta-do-cartucho do milho, em laboratório. Bioensaios com diferentes concentrações de extrato em dieta artificial, tendo o inseticida chlorpyrifos como testemunha, revelaram, 15 dias após infestação com larvas, eficiência equivalente entre as concen- trações 3,60 a 10,00 mg mL-1. A análise de Probit mostrou CL50 = 2,67 mg mL-1; o extrato aquoso das folhas de nim apresenta, portanto, efeito inseticida sobre a lagarta-do-cartucho do milho.The fall armyworm (Spodoptera frugiperda (J. E. Smith has been controlled with synthetic insecticides bringing risk to the environment. Neem (Azadirachta indica A. Juss is reported to be a natural alternative to synthetic insecticides against many insect species. The objective of this work was to evaluate the activity of neem leaves aqueous extract on fall armyworm, in laboratory. Bioassays carried out using artificial feed with various extract concentrations, and chlorpyrifos as control, indicated, 15 days after larvae infestation, similar efficiency in concentrations from 3.60 to 10.00 mg mL-1. Probit analysis showed LC50 = 2.67 mg mL-1. Hence, aqueous extract from neem leaves are active against fall armyworm.

  4. Use of nanostructure initiator mass spectrometry (NIMS to deduce selectivity of reaction in glycoside hydrolases

    Directory of Open Access Journals (Sweden)

    Kai eDeng

    2015-10-01

    Full Text Available Chemically synthesized nanostructure-initiator mass spectrometry (NIMS probes derivatized with tetrasaccharides were used to study the reactivity of representative Clostridium thermocellum β-glucosidase, endoglucanases and cellobiohydrolase. Diagnostic patterns for reactions of these different classes of enzymes were observed. Results show sequential removal of glucose by the β-glucosidase and a progressive increase in specificity of reaction from endoglucanases to cellobiohydrolase. Time-dependent reactions of these polysaccharide-selective enzymes were modeled by numerical integration, which provides a quantitative basis to make functional distinctions among a continuum of naturally evolved catalytic properties. Consequently, our method, which combines automated protein translation with high-sensitivity and time-dependent detection of multiple products, provides a new approach to annotate glycoside hydrolase phylogenetic trees with functional measurements.

  5. Low power CAMAC and NIM modular systems for spaceflight use on Shuttle and Spacelab missions

    Energy Technology Data Exchange (ETDEWEB)

    Trainor, J.H.; Kaminski, T.J.; Ehrmann, C.H.

    1977-02-01

    The advent of the Shuttle launch vehicle and Spacelab have resulted in adequate weight and volume such that experiment electronics can be implemented at relatively low cost using spaceflight versions of CAMAC and NIM modules. Studies of 10 modules by manufacturers have shown that power reduction overall by a factor of approximately 3 can be accomplished. This is adequate both from the point of view of consumption and temperature rise in vacuum. Our studies have shown that a stock of approximately 45 module types is required and a listing is given. The changes required in these modules in order to produce spaceflight versions are described. And finally, the further studies, prototyping and testing leading to eventual flight qualification are described.

  6. Pengaruh Capital Adequacy Ratio (CAR, Beban Operasional Pendapatan Operasional (BOPO, Return on Asset (ROA dan Net Interest Margin (NIM terhadap Financing Deposit Ratio (FRD di PT. BPRS Bhakti Sumekar Sumenep (Periode 2011-2015

    Directory of Open Access Journals (Sweden)

    Cholida Noerainon

    2016-06-01

    Full Text Available The Bank is an industry whose business activities relying on public confidence so that the health of banks is done by maintaining the quality so that the bank can meet its obligations and maintain its performance. The purpose bank will be realized if the bank is able to significantly improve their performance optimal. To be able to function properly, the banks should have enough capital, maintaining its asset quality with a good, well-managed and operated by the precautionary principle thus generate enough profit to maintain the continuity of its business and maintain its liquidity so that it can meet its obligations at any time. the purpose of this study is the first: To determine the effect of the Capital Adequacy Ratio (CAR, Operating Expenses Towards Operating Income (OEOI, Return on Assets (ROA and Net Interest Margin (NIM simultaneously to the Financial to Deposit Ratio (FDR PT. BPRS Bhakti Sumekar Sumenep. Second: To determine the effect of the Capital Adequacy Ratio (CAR, Operating Expenses Towards Operating Income  (OEOI, Return on Assets (ROA and Net Interest Margin (NIM partially on Financial to Deposit Ratio (FDR PT. BPRS Bhakti Sumekar Sumenep. Third: To determine which variables are the most dominant influencing on Financial to Deposit Ratio (FDR at PT. BPRS Bhakti Sumekar Sumenep. In this research uses quantitative methods with the technique of multiple linear regression analysis with the help of SPSS analysis tools, while proving the hypothesis using a calculation T test and F test. The data used is secondary data namely quarterly publication report documentation results. The research results shows that the variables CAR, OEOI, ROA and NIM simultaneously no effect  towards FDR PT. BPRS Bhakti Sumekar Sumenep because Sig. > 0.05 and the value of Fcount

  7. On a Clear Day, You Can See ICS: The Dying Art of Incident Command and the Normal Accident of NIMS - A Policy Analysis

    Science.gov (United States)

    2013-03-01

    Commander ICS Incident Command System IMT Incident Management Team MACC Multi-Agency Coordination System MACS Multi-Agency Coordination System NIMS...as a nation to respond to the big (and little) ones. I do not propose that these three policy options are all-inclusive, as there are many more...Giuliani rose to the occasion and became known as “America’s Mayor” for his leadership during the events ( Economist , 2005). The city of New York

  8. Toxicidade de extratos de nim (Azadirachta indica ao ácaro-vermelho-do-cafeeiro Oligonychus ilicis Toxicity of neem extracts (Azadirachta indica to the coffee red mite Oligonychus ilicis

    Directory of Open Access Journals (Sweden)

    Sheila Abreu Mourão

    2004-08-01

    Full Text Available O objetivo deste trabalho foi estudar a toxicidade aguda e crônica de extratos de óleo de torta, de sementes e de folhas de Azadirachta indica A. Juss (nim a fêmeas do ácaro-vermelho-do-cafeeiro Oligonychus ilicis (McGregor (Acari: Tetranychidae. A mortalidade e a taxa instantânea de crescimento populacional de fêmeas adultas desse ácaro foram avaliadas em discos de folhas de cafeeiro com 3,5 cm de diâmetro, impregnados com resíduo seco dos extratos de nim e flutuando em água. As concentrações dos extratos de óleo de torta, sementes e folhas de nim que mataram 50% e 99% dos indivíduos de O. ilicis, após 72 horas de exposição, foram de 0,02, 15,9 e 121,4 mg/mL e de 10,9, 520,9 e 277,4 mg/mL, respectivamente. A taxa instantânea de crescimento populacional de O. ilicis diminuiu, linearmente, com o aumento da concentração dos extratos de óleo de torta, sementes e folhas de nim até 0,075, 15 e 144 mg/mL, respectivamente, a partir das quais as populações desse ácaro foram extintas.The objective of this work was to study the toxicity of extracts of oil cake, seeds and leaves of Azadirachta indica A. Juss (neem to the coffee red mite Oligonychus ilicis (McGregor (Acari: Tetranychidae. Concentration-mortality and instantaneous rate of populational growth were determined for adult females of the red mite on disks of coffee with 3.5 cm diameter, floating on water and impregnated with dry residues of the neem extracts. Concentrations of these extracts which caused 50% mortality of the individuals of O. ilicis were 0.02, 15.9 and 121.4 mg/mL; while 99% mortality of this mite was reached with 10.9, 520.9 and 277.4 mg/mL for oil cake, seeds and leaves extracts, respectively. The instantaneous rate of populational growth of O. ilicis dropped as the extract doses increased up to 0.075, 15 and 144 mg/mL for oil cake, seeds and leaves extracts, respectively.

  9. Efeito inseticida sistêmico de nanoformulações à base de nim sobre Bemisia tabaci (Hemiptera: Aleyrodidae biótipo B em tomateiro

    Directory of Open Access Journals (Sweden)

    Sheila Salles de Carvalho

    2015-01-01

    Full Text Available Este estudo avaliou a ação inseticida sistêmica e o efeito residual de nanoformulações à base de derivados de nim (Azadirachta indica A. Juss, Meliaceae sobre ninfas de Bemisia tabaci biótipo B (Hemiptera: Aleyrodidae, espécie-praga de diversas culturas de importância econômica. Suspensões coloidais contendo nanocápsulas carregadas com produtos derivados de A. indica foram preparadas utilizando polímeros biodegradáveis como poli-ε-caprolactona (PCL e poli-β-hidroxibutirato (PHB. A matriz encapsulada era composta por uma formulação comercial contendo uma quantidade enriquecida e conhecida dos limonoides azadiractina e 3-tigloilazadiractol (Azamax® 1,2 CE. Inicialmente foi estimada a CL50, para ninfas de B. tabaci, de soluções contendo óleo de nim, que foram aplicadas via água de irrigação (solo em tomateiro. Posteriormente, dois lotes de nanoformulações, com variação no tipo e quantidade dos polímeros e na quantidade do óleo comercial, foram testados quanto à ação sistêmica. As nanoformulações NC L5-2 (com nanocápsulas de PCL e NC L6-1 (com nanocápsulas de PHB, as mais eficazes entre as testadas, foram avaliadas quanto ao efeito residual. A CL50 estimada foi de 180,67 mg L–1 de azadiractina. Constatou-se também que a ação sistêmica de óleos e nanoformulações contendo compostos de nim dependem das condições ambientais em que são aplicados. O Azamax® não apresenta efeito deterrente sobre a oviposição, nem age sobre o desenvolvimento embrionário da mosca-branca quando aplicado via água de irrigação no solo no momento da infestação. As nanoformulações selecionadas são bioativas mesmo cerca de 30 dias após a aplicação, não diferindo do produto comercial.

  10. A noise thermometry investigation of the melting point of gallium at the NIM

    Science.gov (United States)

    Zhang, J. T.; Xue, S.

    2006-06-01

    This paper describes a study of the melting point of gallium with the new NIM Johnson noise thermometer (JNT). The new thermometer adopts the structure of switching correlator and commutator with the reference resistor maintained at the triple point of water. The electronic system of the new thermometer is basically the same as the current JNT, but the preamplifiers have been improved slightly. This study demonstrates that examining the characteristics of the noise signals in the frequency domain is of critical importance in constructing an improved new thermometer, where a power spectral analysis is found to be critical in establishing appropriate grounding for the new thermometer. The new JNT is tested on measurements of the thermodynamic temperature of the melting point of gallium, which give the thermodynamic temperature of 302.9160 K, with an overall integration time of 190 h and a combined standard uncertainty of 9.4 mK. The uncertainty analysis indicates that a standard combined uncertainty of 3 mK could be achieved with the new thermometer over an integration period of 1750 h.

  11. Case report: unusual dental morphology in a child with ankyloblepharon-ectodermal defects-cleft lip/palate (AEC) syndrome.

    LENUS (Irish Health Repository)

    Fitzgerald, K

    2012-02-01

    BACKGROUND: Anomalies of dental anatomy are common in the ectodermal dysplasia syndromes. These anomalies, when found in combination with dental caries, can pose a restorative challenge for the paediatric dentist. Modification of traditional techniques and approaches may help the practitioner provide a successful treatment outcome. CASE REPORT: A 3 years and 11 months old girl with a diagnosis of ankyloblepharon-ectodermal dysplasiacleft lip\\/palate (AEC) syndrome was referred for treatment to a specialist paediatric dental service. Her abnormal dental anatomy, hypodontia and dental caries formed a triad of challenges for the team. Under general anaesthesia, her dentition was restored using a combination of restorative approaches and techniques, including the placement of both composite resin and preformed metal crown restorations. FOLLOW-UP: At 18-month followup, the family had successfully implemented good home care and dietary practices, and the local dental service had instituted a preventive programme consisting of regular examination, advice and fluoride varnish placement. The restorations remained intact and no further caries was detected. At 24-month follow-up, the first permanent molars were partially erupted, and displayed unusually deep fissures. There was also a degree of ectopic eruption of the first permanent molars, and possibly of one of the maxillary permanent incisors. CONCLUSION: Dental care for children with AEC syndrome is optimised by early intervention, good home care and regular professional review. Dental care providers should be aware of the possibility of complex dental anatomy, and bear this in mind should it become necessary to formulate a restorative treatment plan.

  12. Galileo PPR at Io: High Resolution Scans Taken in Conjunction with SSA and NIMS Data

    Science.gov (United States)

    Rathbun, J. A.; Spencer, J. R.; Tamppari, L. K.; Martin, T. Z.; Barnard, L.; Travis, L. D.

    2003-01-01

    The Galileo Photopolarimeter-Radiometer (PPR), when used in the radiometry mode which is most often used at Io, is a long-wavelength infrared single-aperture photometer. It is sensitive to temperatures from about 60 to several hundred K, and is thus useful for studying the volcanoes and background temperatures on Io. PPR can take raster scan images when it is the primary instrument being used (these data were discussed last year, see Rathbun et al., 2002). It can also take data in ride-along mode in conjunction with another remote sensing instrument (either SSI or NIMS) producing one-dimensional temperature scans. The best data of this type were taken during the close approach flybys during orbits I24, I25, I27, I31, I32, and I33 and include measurements of the volcanoes Pele, Prometheus, Pillan, Zamama, Tvashtar, Daedalus, Amarani, Gish Bar, Isum, Emakong, Tupan, and Tohil.

  13. Formerly utilized MED/AEC sites remedial action program. Radiological survey of the West Stands, New Chemistry Lab and Annex, and Ricketts Laboratory, the University of Chicago, Chicago, Illinois, August 31-September 2, 1977

    International Nuclear Information System (INIS)

    Wynveen, R.A.; Smith, W.H.; Mayes, C.B.; Justus, A.L.

    1982-05-01

    A radiological survey was conducted at the former locations of the West Stands, the New Chemistry Lab and Annex, and Ricketts Laboratory at the University of Chicago, Chicago, Illinois. General radiochemistry and/or physics research for the MED/AEC program was performed at these sites during the 1940s. The buildings have since been razed. The survey was undertaken to determine the presence of any radionuclides remaining from the MED/AEC operations that could have been spilled or released from the former structures. Environmental soil samples (corings) were collected from the areas where the West Stands, New Chemistry Lab and Annex, and Ricketts Laboratory once stood. The soil corings were taken at what appeared to be undisturbed locations near the sites of the three former facilities. Analyses of the soil corings included determination of the concentrations of 137 Cs, the 232 Th decay chain, the 226 Ra decay chain, and uranium in the soil. The levels of uranium and the 226 Ra decay chain found in the samples indicated that no concentrations above natural background levels were present. Slightly elevated levels of 60 Co were found in soil taken from the top 5 cm of the ground at two sampling sites, but this activity was presumed to have been traceable to induced activity from contaminated stainless steel that had been stored in the area during operations not related to MED/AEC activities. No increased radiation dose attributable to exposure to residual radioactivity from MED/AEC activities is expected

  14. Eficácia de extratos de nim para o controle do oídio do feijoeiro Effectiveness of neem extracts in controlling the powdery mildew of bean plant

    Directory of Open Access Journals (Sweden)

    Solange Monteiro de Toledo Piza Gomes Carneiro

    2007-03-01

    Full Text Available O nim, Azadirachta indica, vem sendo estudado nos últimos anos para o controle de fitopatógenos. O objetivo deste trabalho foi avaliar o efeito do óleo, do extrato de sementes e do extrato de folhas de nim no controle do oídio do feijoeiro, em casa de vegetação. Uma formulação comercial de óleo emulsionável de nim foi testada em concentrações entre 0,25 e 2,0%, em aplicações antes ou após o surgimento dos sintomas da doença. O extrato de sementes foi produzido em laboratório por meio da trituração das sementes em água destilada, sendo pulverizado 48 horas antes ou 24 horas após a inoculação do patógeno. Avaliou-se, após o surgimento dos sintomas, a eficiência de uma formulação comercial de extrato de folhas, nas concentrações de 0,25 e 0,5%. Verificou-se que o óleo de nim foi eficiente para o controle da doença quando aplicado antes ou depois do surgimento dos sintomas. O extrato de sementes controlou a doença nas três concentrações testadas. Por outro lado, o extrato de folhas não foi eficiente no controle do oídio do feijoeiro.The neem, Azadirachta indica, has been studied in the last years for the use in controlling plant pathogens. The objective of this work was to evaluate the effect of the neem oil, seed kernel extract and leaf extract on the control of the powdery mildew of the bean plant under green house conditions. The emulsified neem oil was tested for concentrations between 0.25 and 2.0% and sprayed before or after the appearance of the symptoms of the disease. The seed kernel extract was produced under laboratory conditions by grinding the kernels in distilled water, which was sprayed 48 hours before or 24 hours after the inoculation of the pathogen. It was also evaluated the efficiency of a commercial leaf extract at the concentrations of 0.25 and 0.5% which was sprayed after the appearance of the symptoms. The results of this work showed that the neem oil was efficient in the control of the

  15. Med humanističnim in poklicnim izobraževanjem ali kaj terja od nas prihodnost

    Directory of Open Access Journals (Sweden)

    Dušana Findeisen

    1996-12-01

    Full Text Available Dušana Findeisen piše o razmerju med humanističnim in poklicnim izobraževanjem v prihodnosti. Ker kvalifikacij, ki bodo potrebne na trgu dela čez petnajst let, ni mogoče z gotovostjo predvideti, lahko razmišljamo predvsem o tem, kakšne ljudi bomo potrebovali: katere bodo bistvene zmožnosti, ki jih bo treba zajeti med cilje izobraževalnih programov mladih in odraslih. Med bistvenimi usposobljenostmi navaja obvladovanje miselnih procesov, zmožnost spo­razumevanja, usposobljenost za dejavno življenje v skupnosti , razmerje do okolja itd. Opozarja tudi na potrebo po drugačnih didaktičnih postopkih in drugačnem vrednotenju, da bi zagotovili uravnoteženost izobraževanja. Humanistično izobraževanje bo moralo prodreti tudi v ozko usposabljanje odraslih, saj podjetja ne potrebujejo samo dobrih strokovnjakov, temveč ljudi, ki so se zmožni prilagajati in se razvijati.

  16. Efficacy evaluation of a commercial neem cake for control of Haematobia irritans on Nelore cattle Avaliação da eficácia de uma torta comercial de nim para o controle de Haematobia irritans em bovinos Nelore

    Directory of Open Access Journals (Sweden)

    Ana Carolina de Souza Chagas

    2010-12-01

    Full Text Available Much attention has been given to the development of botanical insecticides to provide effective natural control of cattle ectoparasites without harming animals, consumers, and environment. This study evaluated the efficacy of a commercial neem cake in controlling Haematobia irritans infestation on cattle. The study was conducted at the Embrapa Southeast Cattle Research Center (CPPSE, in São Carlos, SP, Brazil, from April to July 2008. The neem cake mixed in mineral salt in a 2% concentration was provided to 20 Nelore cows during nine weeks and had its efficacy evaluated by comparison of the infestation level against a control group. Fly infestations were recorded weekly by digital photographs of each animal from both groups and the number of flies was later counted in a computer-assisted image analyzer. Quantification of neem cake components by high-performance liquid chromatography revealed the presence of azadirachtin (421 mg.kg-1 and 3-tigloyl-azadirachtol (151 mg.kg-1 in the tested neem cake. Addition of the 2% neem cake reduced mineral salt intake in about 22%. The 2% neem cake treatment failed to reduce horn fly infestations on cattle during the 9-week study period.Muita atenção tem sido dada ao desenvolvimento de inseticidas vegetais buscando-se um efetivo controle de ectoparasitas de bovinos, sem prejudicar animais, consumidores e meio ambiente. Este estudo, realizado de abril a julho de 2008, na Embrapa Pecuária Sudeste, em São Carlos, SP, Brasil, avaliou a eficácia de uma torta comercial de nim (Azadirachta indica no controle da mosca-dos-chifres (Haematobia irritans em bovinos. A torta de nim, misturada ao sal mineral na concentração de 2%, foi fornecida a 20 vacas Nelore, durante nove semanas, e sua eficácia foi monitorada através de contagens semanais nos grupos tratado e controle. Infestações individuais foram registradas por meio de fotos digitais em todos os animais de ambos os grupos, e o número de moscas foi

  17. Toward a regional power plant siting method: AEC-Maryland regional siting factors study, FY 1974 progress report

    International Nuclear Information System (INIS)

    Yaffee, S.L.; Miller, C.A.

    1974-11-01

    The ''AEC-Maryland Regional Siting Factors Study'' examines the process of siting in a regional context. It is developing an analysis method to delineate candidate areas for siting of several power plant technology packages, including both fossil-fueled and nuclear options. Tools that are being used include simulation modeling, economic and demographic forecasting, spatial analysis, and computer graphics and numerical manipulation. The approach will describe the trade-offs incurred if a power plant is located in one candidate area rather than in another. In FY 1974, a suitability analysis method was developed which uses engineering and environmental parameters to define a level of environmental cost incurred if a segment of land is used to site a specific technology package. (U.S.)

  18. Cyclosporine A, FK506, and NIM811 ameliorate prolonged CBF reduction and impaired neurovascular coupling after cortical spreading depression

    DEFF Research Database (Denmark)

    Hansen, Henning Piilgaard; Witgen, Brent Marvin; Rasmussen, Peter

    2011-01-01

    Cortical spreading depression (CSD) is associated with mitochondrial depolarization, increasing intracellular Ca(2+), and the release of free fatty acids, which favor opening of the mitochondrial permeability transition pore (mPTP) and activation of calcineurin (CaN). Here, we test the hypothesis...... and the specific CaN blocker FK506. Cortical spreading depression was induced in rat frontal cortex. Electrocortical activity was recorded by glass microelectrodes, CBF by laser Doppler flowmetry, and tissue oxygen tension with polarographic microelectrodes. Electrocortical activity, basal CBF, CMRO(2......), and neurovascular and neurometabolic coupling were unaffected by all three drugs under control conditions. NIM811 augmented the rise in CBF observed during CSD. Cyclosporine A and FK506 ameliorated the persistent decrease in CBF after CSD. All three drugs prevented disruption of neurovascular coupling after CSD...

  19. An Evaluation of Indonesian Capital Market Co-integration with ASEAN 4 to Enter the ASEAN Capital Market Integration in Accordance to ASEAN Economic Community (AEC 2020 Scheme: Should Indonesia Enter or Postpone?

    Directory of Open Access Journals (Sweden)

    Barli Suryanta

    2014-08-01

    Full Text Available Association of South East Asian Nations (ASEAN Economic Community (AEC 2020 has already been declared on 7 October 2003 by ASEAN Concord II in Bali, Indonesia. In general, AEC was designed to prepare ASEAN countries for ASEAN economic integration within the next 10-15 year. ASEAN Free Trade  Area (AFTA  had  actually  been  launched since 1992 though was not comprehensive enough and kept ASEAN only partially integrated. To overcome it, ASEAN proposed  inancial  integration  through  capital market  integration based on AEC commitment in order to reach comprehensive ASEAN economic integration. Indonesia is one of the  ASEAN  members  that  is  linked  by AEC  2020.  The  purpose  of  this paper is to evaluate Indonesian capital market co-integration in entering the ASEAN capital market integration compared to those of ASEAN 4. To examine the notion of the Indonesian capital  market  integration  within ASEAN  region, cointegration model  is  utilised  to  igure out co-integration between Indonesian stock market indices and ASEAN 4, i.e., Singapore, Malaysia, Philippines and Thailand. In addition, Vector Auto-regression (VAR model is also utilised to examine Indonesian market returns co-movement and dynamic link with ASEAN 4.  The  conclusions  of  this  research,  i.e.  co-integration  between  Indonesian  capital  market with  Singaporean,  Malaysian,  Philippines,  and  Thailand  does  not  exist;  there  is  neither co-movement  nor  strong  dynamic  link  between  Indonesian  capital  market  with  those  of Singaporean, Malaysian, Philippines, and Thailand. This paper also recommends Indonesia to postpone the integration of its capital market into the integrated ASEAN capital market. ";} // -->activate javascript

  20. Macro-IML manual for DEC PDP 11 computer with controller DEC CA 11-A/BORER type 1,533 A

    International Nuclear Information System (INIS)

    Kubitz, M.; Kind, R.

    1975-03-01

    The IML-implementations follow the Macro-Syntax as given in Appendix A of the document 'CAMAC. The Definitior of IML (A Language For Use in CAMAC Systems)'. This document has been adopted as a description by ESONE and AEC NIM in August/September 74 and has been published in October 74. They have been designed for the DEC PDP 11 computer with the branch controller DEC CA 11-A and the Single Crate Controller BORER Type 1,533 A. For both DEC operating systems, DOS V08/09 and RSX-11D/M a full set of macros has been implemented except the block transfer on special LAM, X-error control statements and the subscript mode. Transfer modes not implemented by the hardware of the CA 11-A are simulated by software. (orig.) [de

  1. Basic data report for drillhole AEC 8 (Waste Isolation Pilot Plant - WIPP)

    International Nuclear Information System (INIS)

    1983-01-01

    AEC 8 was originally drilled in 1974 to a depth of 3028 ft by Oak Ridge National Laboratory as part of the initial investigations of a site for radioactive waste disposal. In 1976, Sandia National Laboratories deepened the borehole from the top of the Castile Formation into the Bell Canyon Formation to test the hydraulic properties of the Bell Canyon. The borehole encountered in descending order Holocene sands (20 ft), Mescalero caliche (6 ft), Santa Rosa Sandstone (143 ft), Dewey Lake Redbeds (491 ft), Rustler Formation (322 ft), Salado Formation (1990 ft), Castile Formation (1335 ft), and the upper Bell Canyon Formation (603 ft). The borehole stratigraphy is in normal order and there is no significant deformation. An extensive suite of geophysical logs provides information on the lithology and stratigraphy. The potentiometric surfaces of Bell Canyon fluid-bearing zones are 550 ft (for the zone at 4821 ft to 4827 ft) and 565 ft below land surface (for the zone at 4844 to 4860 ft). The WIPP is a demonstration facility for the disposal of transuranic (TRU) waste from defense programs. The WIPP will also provide a research facility to investigate the interactions between bedded salt and high level wastes

  2. AEC authorizing legislation, fiscal year 1975. Part 3. Hearings before the Joint Committee on Atomic Energy, Congress of the United States, Ninety-Third Congress, Second Session on Physical Research and Regulatory, February 28, 1974

    International Nuclear Information System (INIS)

    1974-01-01

    This volume contains testimony on the proposed budget for the physical research program presented at public hearings of the Joint Committee on Atomic Energy on the proposed AEC authorizing legislation for fiscal year 1975. Atomic Energy Commission witnesses were Commissioner William O. Doub; Director of Regulation L. Manning Muntzing; Dr. Wolfgang K. H. Panofsky, Director, SLAC; Dr. John M. Teem, Assistant General Manager for Physical Research and Laboratory Coordination; and Dr. Robert R. Wilson, Director, NAL. Other witnesses included B. James Porter, Donald C. Gilbert, Hon. Sterling Cole, and Wyatt M. Rogers, Jr. Prepared statements, questions and answers, a letter from AEC Chairman Ray, and the report of the ad hoc panel on heavy-ion facilities are included. (U.S.)

  3. Some aspects of the distribution and dynamics of the benthic macroinvertebrate groups from Nimăieşti valley river

    Directory of Open Access Journals (Sweden)

    CUPŞA Diana

    2005-09-01

    Full Text Available In the Nimăieşti Valley river we found in a number of four sample sites a community of benthic macroinvertebrates represented by Oligochaeta, Ephemeroptera larva, Trichoptera larva, Chironomida larva and Hidracarina species. The communities structure vary depending on season and the sampling site acording to the water quality and trophic condition of the substrate. The greatest diversity was recorded during the summer months (may-august and comparing the sample sites, we found that the first three sampling sites are very similar from the point of view of the macroinvertebrate community, but the fourth sampling site the community is different because the river pases through the town of Beiuş and as a consequence the water quality is lower that at the other three sample sites.

  4. ANALISIS SEBARAN RADIONUKLIDA PADA KONDISI NORMAL UNTUK REAKTOR AEC 1000 MW

    Directory of Open Access Journals (Sweden)

    Sri Kuntjoro

    2015-03-01

    Full Text Available Telah dilakukan analisis sebaran radionuklida pada reaktor daya Atomic Energy Agency (AEC 3568 MWTh, setara dengan 1000 Mwe untuk kondisi operasi normal. Analisis dilakukan untuk dua reaktor yang terpisah sejauh 500 m dan sudut 90o satu dengan yang lain. Langkah awal dalam melakukan analisis adalah menentukan suku sumber reaktor menggunakan program komputer ORIGEN2 dan EMERALD NORMAL. ORIGEN2 digunakan untuk menentukan inventori radionuklida yang terdapat di reaktor. Selanjutnya dengan dengan menggunakan program EMERALD NORMAL dihitung suku sumber yang sampai ke cerobong reaktor. Untuk menganalisis dosis yang diterima penduduk dilakukan dengan menggunakan program PC-CREAM. Perhitungan dilakukan untuk satu dan dua PLTN di calon tapak PLTN. Hasil yang diperoleh adalah sebaran radionuklida terbesar untuk satu PLTN pada jarak 1 km dan kearah zona 9 (191,25o dan untuk dua PLTN pada jarak 1 km dan kearah zona 10 (213,75o. Radionuklida yang sampai ke penduduk melalui dua alur yaitu alur makanan dan hirupan. Untuk alur makanan berasal dari radionuklida I-131, dan terbesar melalui alur produk susu sebesar 53,40 % untuk satu maupun dua PLTN . Untuk alur hirupan ranionuklida pemberi kontribusi paparan terbesar berasal dari Kr-85m sebesar 53,80 %. Dosis total terbesar yang diterima penduduk terdapat pada jarak 1 Km untuk bayi yaitu sebesar 4,10 μSi dan 11,26 μSi untuk satu dan dua PLTN. Hasil ini sangat kecil dibandingkan dengan batas dosis yang diijinkan oleh badan pengawas (BAPETEN untuk penduduk yaitu sebesar 1 mSi. Kata Kunci : Reaktor daya, komputer code, radionuklida, alur makanan, hirupan   Analysis for radionuclide dispersion for the Atomic Energy Agency (AEC 3568 MWth Power Reactor, equal to the 1000 MWe at normal condition has been done. Analysis was done for two piles that is separated by 500 m distance and angle of 90o one to other. Initial pace in doing the analysis is to determine reactors source term using ORIGEN2 and EMERALD NORMAL

  5. Radiocesium concentrations of snakes from contaminated and non-contaminated habitats of the AEC Savannah River Plant

    International Nuclear Information System (INIS)

    Brisbin, I.L. Jr.; Staton, M.A.; Pinder, J.E. III.; Geiger, R.A.

    1974-01-01

    Concentration levels of 134 Cs and 137 Cs were determined for 117 snakes of 19 species collected on the AEC Savannah River Plant near Aiken, South Carolina. Snakes collected from the vicinity of a reactor effluent stream averaged 131.5 pCi radiocesium/g live weight, with a maximum of 1032.6 pCi/g, and represented the highest level of radiocesium concentration reported in the literature for any naturally-occurring wild population of vertebrate predators. These snakes had significantly higher concentrations of radiocesium than those collected in the vicinity of a reactor cooling reservoir which averaged 27.7 pCi/g live weight, with a maximum of 139.3 pCi/g. The radiocesium contents of snakes collected from uncontaminated habitats averaged 2.6 and 2.4 pCi/g live weight, respectively, and did not differ significantly from background radiation levels. Radiocesium concentrations approximated a log-normal frequency distribution, and no significant differences in frequency-distribution patterns could be demonstrated between collection areas. (U.S.)

  6. Description of radiological problems at inactive uranium mill sites and formerly utilized MED/AEC sites

    International Nuclear Information System (INIS)

    Jacobs, D.G.; Dickson, H.W.

    1979-02-01

    During the early years of development of the nuclear program in the United States, more than a hundred sites were used by the Manhattan Engineer District (MED), and the U.S. Atomic Energy Commission (AEC), and/or its uranium suppliers. Many of these sites are no longer used for such activities, but in many cases, the real estate remains contaminated with radioactivity and can be a potential source of exposure to members of the general public. In addition, 22 inactive uranium mill tailings sites exist in the western part of the United States. Radioactive contamination conditions range from slight contamination on the surfaces of buildings and equipment to extensive contamination of the subsoil. The Department of Energy is conducting a program to assure that adequate precautions are taken in the management of these properties to provide the cost-effective protection of public health while permitting further use of land and other resources. Several issues which should be considered in the development of an effective policy for long-term management of such properties are identified

  7. Description of radiological problems at inactive uranium mill sites and formerly utilized MED/AEC sites

    Energy Technology Data Exchange (ETDEWEB)

    Jacobs, D.G.; Dickson, H.W.

    1979-02-01

    During the early years of development of the nuclear program in the United States, more than a hundred sites were used by the Manhattan Engineer District (MED), and the U.S. Atomic Energy Commission (AEC), and/or its uranium suppliers. Many of these sites are no longer used for such activities, but in many cases, the real estate remains contaminated with radioactivity and can be a potential source of exposure to members of the general public. In addition, 22 inactive uranium mill tailings sites exist in the western part of the United States. Radioactive contamination conditions range from slight contamination on the surfaces of buildings and equipment to extensive contamination of the subsoil. The Department of Energy is conducting a program to assure that adequate precautions are taken in the management of these properties to provide the cost-effective protection of public health while permitting further use of land and other resources. Several issues which should be considered in the development of an effective policy for long-term management of such properties are identified.

  8. Proceedings of the 5th workshop of 'quantum complex phenomena, -superconductivity, magnetism and phonon-' under the NIMS-RIKEN-JAEA cooperative research program on quantum beam science and technology

    International Nuclear Information System (INIS)

    Shamoto, Shin-ichi; Kodama, Katsuaki

    2012-08-01

    The 5th workshop of the NIMS-RIKEN-JAEA Cooperative Research Program 'Quantum Complex Phenomena, -Superconductivity, Magnetism and Phonon-' was held on January 23-24, 2012 at KKR Hakone Miyanoshita. This workshop is aimed to reveal the mechanism of quantum complex phenomena for the developments of next generation functional materials on the basis of 'Joint Research Agreement for the Pioneering R and D with Quantum Beam Technology' concluded by NIMS, RIKEN and JAEA on December 20, 2006. The neutron facilities in Tokai, i.e., the research reactor JRR-3 and the proton accelerator J-PARC (Japan Proton Accelerator Research Complex), were damaged by the Tohoku-Kanto earthquake on March 11, 2011. J-PARC members' devoted efforts for the recovery made it possible to successfully produce neutron beam in the midnight of January 24, just after this workshop. Also at JRR-3 all the repair works of the reactor facilities and buildings have been completed by the end of the fiscal year 2011. Yet, the safety analysis report is to be submitted and after its positive review by the national regulatory authority, the JRR-3 can undergo the regular periodic inspection to resume its operation. Under this circumstance, characteristic technologies, instruments, and distinguished researches of each institute about 'Superconductivity, Magnetism and Phonon' are introduced and discussed in addition to research outcomes of this Joint Research Agreement including a future prospect of this research area. This report includes abstracts and materials of the presentations in the workshop. (author)

  9. Human Research Program Advanced Exercise Concepts (AEC) Overview

    Science.gov (United States)

    Perusek, Gail; Lewandowski, Beth; Nall, Marsha; Norsk, Peter; Linnehan, Rick; Baumann, David

    2015-01-01

    Exercise countermeasures provide benefits that are crucial for successful human spaceflight, to mitigate the spaceflight physiological deconditioning which occurs during exposure to microgravity. The NASA Human Research Program (HRP) within the Human Exploration and Operations Mission Directorate (HEOMD) is managing next generation Advanced Exercise Concepts (AEC) requirements development and candidate technology maturation to Technology Readiness Level (TRL) 7 (ground prototyping and flight demonstration) for all exploration mission profiles from Multi Purpose Crew Vehicle (MPCV) Exploration Missions (up to 21 day duration) to Mars Transit (up to 1000 day duration) missions. These validated and optimized exercise countermeasures systems will be provided to the ISS Program and MPCV Program for subsequent flight development and operations. The International Space Station (ISS) currently has three major pieces of operational exercise countermeasures hardware: the Advanced Resistive Exercise Device (ARED), the second-generation (T2) treadmill, and the cycle ergometer with vibration isolation system (CEVIS). This suite of exercise countermeasures hardware serves as a benchmark and is a vast improvement over previous generations of countermeasures hardware, providing both aerobic and resistive exercise for the crew. However, vehicle and resource constraints for future exploration missions beyond low Earth orbit will require that the exercise countermeasures hardware mass, volume, and power be minimized, while preserving the current ISS capabilities or even enhancing these exercise capabilities directed at mission specific physiological functional performance and medical standards requirements. Further, mission-specific considerations such as preservation of sensorimotor function, autonomous and adaptable operation, integration with medical data systems, rehabilitation, and in-flight monitoring and feedback are being developed for integration with the exercise

  10. Formerly utilized MED/AEC sites remedial action program: radiological survey of the Museum of Science and Industry, 57th Street and Lake Shore Drive, Chicago, Illinois. Final report

    International Nuclear Information System (INIS)

    1979-02-01

    From August 15, 1946 until July 15, 1953, ANL occupied part of the Museum of Science and Industry in Chicago; some handling of radioactive materials took place. In a radiation survey taken of the areas in 1977, instrument and smear surveys were made, and air and soil samples were counted. Results indicate there is no identifiable residual radioactivity remaining from MED/AEC operations during the period 1946 through 1953

  11. Second Annual AEC Scientific Computer Information Exhange Meeting. Proceedings of the technical program theme: computer graphics

    Energy Technology Data Exchange (ETDEWEB)

    Peskin,A.M.; Shimamoto, Y.

    1974-01-01

    The topic of computer graphics serves well to illustrate that AEC affiliated scientific computing installations are well represented in the forefront of computing science activities. The participant response to the technical program was overwhelming--both in number of contributions and quality of the work described. Session I, entitled Advanced Systems, contains presentations describing systems that contain features not generally found in graphics facilities. These features can be roughly classified as extensions of standard two-dimensional monochromatic imaging to higher dimensions including color and time as well as multidimensional metrics. Session II presents seven diverse applications ranging from high energy physics to medicine. Session III describes a number of important developments in establishing facilities, techniques and enhancements in the computer graphics area. Although an attempt was made to schedule as many of these worthwhile presentations as possible, it appeared impossible to do so given the scheduling constraints of the meeting. A number of prospective presenters 'came to the rescue' by graciously withdrawing from the sessions. Some of their abstracts have been included in the Proceedings.

  12. [Study of CT Automatic Exposure Control System (CT-AEC) Optimization in CT Angiography of Lower Extremity Artery by Considering Contrast-to-Noise Ratio].

    Science.gov (United States)

    Inada, Satoshi; Masuda, Takanori; Maruyama, Naoya; Yamashita, Yukari; Sato, Tomoyasu; Imada, Naoyuki

    2016-01-01

    To evaluate the image quality and effect of radiation dose reduction by setting for computed tomography automatic exposure control system (CT-AEC) in computed tomographic angiography (CTA) of lower extremity artery. Two methods of setting were compared for CT-AEC [conventional and contrast-to-noise ratio (CNR) methods]. Conventional method was set noise index (NI): 14and tube current threshold: 10-750 mA. CNR method was set NI: 18, minimum tube current: (X+Y)/2 mA (X, Y: maximum X (Y)-axis tube current value of leg in NI: 14), and maximum tube current: 750 mA. The image quality was evaluated by CNR, and radiation dose reduction was evaluated by dose-length-product (DLP). In conventional method, mean CNRs for pelvis, femur, and leg were 19.9±4.8, 20.4±5.4, and 16.2±4.3, respectively. There was a significant difference between the CNRs of pelvis and leg (P<0.001), and between femur and leg (P<0.001). In CNR method, mean CNRs for pelvis, femur, and leg were 15.2±3.3, 15.3±3.2, and 15.3±3.1, respectively; no significant difference between pelvis, femur, and leg (P=0.973) in CNR method was observed. Mean DLPs were 1457±434 mGy⋅cm in conventional method, and 1049±434 mGy·cm in CNR method. There was a significant difference in the DLPs of conventional method and CNR method (P<0.001). CNR method gave equal CNRs for pelvis, femur, and leg, and was beneficial for radiation dose reduction in CTA of lower extremity artery.

  13. SU-E-I-91: Reproducibility in Prescribed Dose in AEC CT Scans Due to Table Height, Patient Size, and Localizer Acquisition Order

    International Nuclear Information System (INIS)

    Winslow, J; Hurwitz, L; Christianson, O; Samei, E

    2014-01-01

    Purpose: In CT scanners, the automatic exposure control (AEC) tube current prescription depends on the acquired prescan localizer image(s). The purpose of this study was to quantify the effect that table height, patient size, and localizer acquisition order may have on the reproducibility in prescribed dose. Methods: Three phantoms were used for this study: the Mercury Phantom (comprises three tapered and four uniform regions of polyethylene 16, 23, 30, and 37 cm in diameter), acrylic sheets, and an adult anthropomorphic phantom. Phantoms were positioned per clinical protocol by our chief CT technologist or broader symmetry. Using a GE Discovery CT750HD scanner, a lateral (LAT) and posterior-anterior (PA) localizer was acquired for each phantom at different table heights. AEC scan acquisitions were prescribed for each combination of phantom, localizer orientation, and table height; the displayed volume CTDI was recorded for each. Results were analyzed versus table height. Results: For the two largest Mercury Phantom section scans based on the PA localizer, the percent change in volume CTDI from ideal were at least 20% lower and 35% greater for table heights 4 cm above and 4 cm below proper centering, respectively. For scans based on the LAT localizer, the percent change in volume CTDI from ideal were no greater than 12% different for 4 cm differences in table height. The properly centered PA and LAT localizer-based volume CTDI values were within 13% of each other. Conclusion: Since uncertainty in vertical patient positioning is inherently greater than lateral positioning and because the variability in dose exceeds any dose penalties incurred, the LAT localizer should be used to precisely and reproducibly deliver the intended amount of radiation prescribed by CT protocols. CT protocols can be adjusted to minimize the expected change in average patient dose

  14. Utjecaj jestivog filma od želatine, obogaćenog eteričnim uljem lovora, na kakvoću fileta kalifornijske pastrve (Onchorynchus mykiss) tijekom skladištenja u hladnjaku

    OpenAIRE

    Alparslan, Yunus; Baygar, Tuba; Baygar, Taçnur; Hasanhocaoglu, Hatice; Metin, Cansu

    2014-01-01

    U ovom je radu ispitan utjecaj filma od želatine, obogaćenog eteričnim uljem lovorovog lista, na kakvoću fileta kalifornijske pastrve (Onchorynchus mykiss) skladištene na (4±1) °C tijekom 26 dana. Fileti su ribe omotani u filmove od 8 %-tne želatine, koji su sadržavali 0; 0,1 ili 1 % (volumena po masi želatine) eteričnog ulja lovora, te pakirani u vakuumu. Tijekom skladištenja određivani su: senzorske značajke sirove i kuhane ribe, mikrobiološki parametri (ukupan broj živih stanica, te bro...

  15. Historical nuclear materials balance report for the former AEC-owned Weldon Spring Chemical Plant, Weldon Spring, Missouri

    International Nuclear Information System (INIS)

    Harris, R.A.

    1986-07-01

    From June 1957 through December 1966, four types of nuclear material were processed in the AEC-owned Weldon Spring Chemical Plant. These materials were: (1) natural uranium, (2) depleted uranium, (3) slightly enriched uranium, and (4) natural thorium. The summary material balances for each material are shown in Table 1. In processing these materials, discards occurred to (a) the atmosphere through stacks, (b) area waterways through sewers, and (c) to raffinate pits still in existence at the site. These discards are summarized in Table 2. Natural uranium processing accounted for more than 97% of the nuclear materials throughput (Table 1). Total material balance closures for natural uranium, depleted uranium, slightly enriched uranium, and natural thorium were 99.94%, 100%, 99.27%, and 98.52%, respectively. Of the discards, summarized in Table 2, approximately 75% went to and remain in the existing raffinate pits. Discharges to stacks and sewers account for the remaining discards. As far as can be determined, it appears all plant processes operated efficiently and all materials were well accounted for with only minimal variances

  16. A NIM (Nuclear Instrumentation Module) system conjugated with optional input for pHEMT amplifier for beta and gamma spectroscopy; Um sistema de modulos NIM conjugados com entrada opcional por amplificador pHEMT para espectroscopia beta e gama

    Energy Technology Data Exchange (ETDEWEB)

    Konrad, Barbara; Lüdke, Everton, E-mail: barbarakonradmev@gmail.com, E-mail: eludke@smail.ufsm.br [Universidade Federal de Santa Maria (LAE/UFSM), RS (Brazil). Lab. de Astrofisica e Eletronica

    2014-07-01

    This work presents a high speed NIM module (Nuclear Instrumentation Module) to detect radiation, gamma and muons, as part of a system for natural radiation monitoring and of extraterrestrial origin. The subsystem developed consists of a preamplifier and an integrated SCA (Single Channel Analyzer), including power supplies of ± 12 and ± 24V with derivations of +3.6 and ± 5V. The single channel analyzer board, consisting of discrete logic components, operating in window modes, normal and integral. The pulse shaping block is made up of two voltage comparators working at 120 MHz with a response time > 60 ns and a logic anticoincidence system. The preamplifier promotes a noise reduction and introduces the impedance matching between the output of anode / diode photomultiplier tubes (PMTs) and subsequent equipment, providing an input impedance of 1MΩ and output impedance of 40 to 140Ω. The shaper amplifier is non-inverting and has variable input capacitance of 1000 pF. The upper and lower thresholds of the SCA are adjustable from 0 to ± 10V, and the equipment is compatible with various types of detectors, like PMTs coupled to sodium iodide crystals. For use with liquid scintillators and photodiodes with crystals (CsI: Tl) is proposed to include a preamplifier circuit pHEMT (pseudomorphic High Electron Mobility Transistor) integrated. Yet, the system presents the possibility of applications for various purposes of gamma spectroscopy and automatic detection of events producing of beta particles.

  17. Analysis of radionuclide dispersion at normal condition for AEC 1000 MW reactor power

    International Nuclear Information System (INIS)

    Sri Kuntjoro

    2010-01-01

    Analysis for radionuclide dispersion for the Atomic Energy Agency (AEC) 3,568 MWth Power Reactor, equal to the 1,000 MWe at normal condition has been done. Analysis was done for two piles that is separated by 500 m distance and angle of 90° one to other. Initial pace in doing the analysis is to determine reactors source term using ORIGEN2 and EMERALD NORMAL. computer code program. ORIGEN2 applied to determine radionuclide inventory emerged in the reactor. Hereinafter, by using Emerald Normal Computer code is calculated source term reaching the reactor stack. To analyze dose received by population is done by using PC-CREAM computer code. Calculation done for one and two PLTN attached in site candidate of plants. The result showed is that the highest radionuclide release for one PLTN is at 1 km distance and to 9 th zone toward ( 19.25° ) and for two PLTN is at 1 km distance and to 10 th zone toward (21.75° ). Radionuclide which up to population through two pathways that are foodstuff and inhalation. To foodstuff comes from radionuclide I 131 , and the biggest passed from milk product with 53.40 % for one and also two PLTN For inhalation pathway the highest radionuclide contribution come from Kr 85m is about 53.80 %. The highest total dose received by population is at 1 Km distance received by baby that is 4.10 µSi and 11.26 µSi for one and two PLTN respectively. Those result are very small compared to the maximum permission dose to population issued by regulatory body that is equal to 1 mSi. (author)

  18. Efficiency of neem oil nanoformulations to Bemisia tabaci (GENN. Biotype B (Hemiptera: AleyrodidaeEficiência de nanoformulações a base de óleo de nim sobre Bemisia tabaci (GENN. Biótipo B (Hemiptera: Aleyrodidae

    Directory of Open Access Journals (Sweden)

    Sheila Salles Carvalho

    2012-04-01

    Full Text Available The nanotechnology, through encapsulation of active ingredients, has showed an important way to avoid problems with quickly degradation of the pesticide molecules. Thus, neem (Azadirachta indica oil nanoformulations containing ?-ciclodextrin and poli-?-caprolactone (PCL were tested as to their control efficiency against eggs and nymphs of Bemisia tabaci (Genn. biotype B reared in soybean. The Lethal Concentration (LC50 was estimated using a commercial neem oil (Organic Neem® on first-instar nymphs to establish the adequate volume of the nanoformulations per treatment. After that, they were sprayed on eggs and first-instar nymphs in laboratory and greenhouse and on third-instar nymphs in greenhouse. The commercial neem oil and distilled water were used as controls. Egg viability was not affected by any treatment. Among six nanoformulations, only one was efficient against the first-instar nymphs in laboratory conditions. However, its effective period was not increased as expected. In greenhouse, first-instar nymphs were more affected by two nanoformulations which were significantly different of the commercial neem oil - the most effective one. No mortality differences among the formulations in the third-instar test were observed. The nanoformulations were less efficient to control the B. tabaci biotype B nymphs than the commercial neem oil. A nanotecnologia, através do encapsulamento de ingredientes ativos, tem-se revelado uma importante estratégia para evitar problemas com a rápida degradação de moléculas inseticidas. Assim, nanoformulações à base de óleo de nim (Azadirachta indica utilizando os polímeros ?-ciclodextrina e poli-?-caprolactona (PCL foram testadas quanto a sua eficiência de controle de ovos e ninfas de Bemisia tabaci (Genn. biótipo B mantidas em soja. Foi estimada a CL50 utilizando uma formulação comecial de óleo de nim (Organic Neem® sobre ninfas em 1º ínstar da qual se estipulou o volume das nanoformula

  19. Organisation of biological research carried out in the United States by the A.E.C. or under her contract (1960)

    International Nuclear Information System (INIS)

    Pellerin, J.

    1960-01-01

    This report is based on information gathered in the course of a trip to the United States, in November and December 1958 which consisted chiefly of visits to the main biological and medical research laboratories and discussions with the heads of these establishments. A description is given of the general organisation of the Atomic Energy Commission's Division of Biology and Medicine, and of the distribution of responsibility for radiation protection work and for biological, medical and agricultural research amongst the various Services attached to it; this is followed by a more detailed account of the activities carried on in this field at the great national laboratories. Finally, the systems of collaboration set up with external research organisations in the form of research contracts are examined, together with the substantial help provided by the A.E.C. for biological, medical and agricultural research in general, owing to a systematic policy of subsidising the distribution of radioisotopes for this purpose. (author) [fr

  20. Formerly utilized MED/AEC sites remedial action program. Radiological survey of Eckhart Hall, the University of Chicago, Chicago, Illinois, September 14, 1976-March 22, 1977

    International Nuclear Information System (INIS)

    Wynveen, R.A.; Smith, W.H.; Boggs Mayes, C.; Justus, A.L.

    1982-05-01

    A comprehensive radiological survey was conducted at the Eckhart Hall at the University of Chicago, Chicago, Illinois. General radiochemistry and/or physics research was performed at this facility during the MED/AEC era in the 1940s. The building is now used as laboratories, offices, and classrooms. Survey measurements included alpha and beta-gamma contamination determinations, both fixed and removable; beta-gamma exposure readings at contact and at 1 m (3 ft); estimates of radon-daughter concentrations in the air; and determination of concentrations of 137 Cs, the 232 Th decay chain, the 226 Ra decay chain, and uranium in the soil on the site. Thirteen spots of contamination were found to be fixed to or under existing surfaces and not readily available for transfer to other locations. Under current use conditions, the potential for radiation exposure to occupants of this building from these sources of contamination is remote. Concentrations of radon daughters in the air of the building were less than the limit of 0.01 Working Level (WL) above background. No long-lived radionuclides were detected in any air sample. Concentrations of radionuclides in soil samples collected around the facility indicated background levels. The presumed maximum potential internal radiation 50-year dose commitments from inhalation/ingestion of contamination remaining from MED/AEC activities were calculated to be less than 25% of the appropriate annual standards for an individual in an uncontrolled area. Remedial measures such as stabilization of the contamination in place would be applicable as a short-term measure. In order to reduce the risk in the event that building modifications take place in the future, health physics procedures and coverage are recommended. The long-term solution would involve decontamination by removal of the radioactive residues

  1. Time Evolution of Io’s volcanoes Pele and Pillan from 1996 - 2015, as derived from Galileo NIMS, Keck, Gemini, IRTF, and LBTI observations

    Science.gov (United States)

    de Pater, Imke

    2015-11-01

    We present highlights of our observations of Pele and Pillan on Io, and a multi-decade timeline of thermal emission intensities in both regions. Io was regularly observed by Galileo NIMS during 1996-2001. Since 2001 the satellite has been imaged semi-regularly with NIRC2, coupled to an adaptive optics system, on the 10-m Keck telescope. In 1997, Galileo NIMS observed a large and highly-variable eruption close to Pillan Mons; this eruption lasted several months [1]. Since that time no eruptions had been seen (but time coverage was scarce), until our Keck images on 14 August 2007 revealed an active and highly-energetic eruption at a location close to that of the 1997 eruptions. A one-temperature blackbody fit to the data revealed a (blackbody) temperature of 840 ± 40 K over an area of 17 km2, with a total power output of ~500 GW. Using Davies’ (1996) Io Flow Model [2] we find that the oldest lava present is less than 1-2 hours old, having cooled down from the eruption temperature of >1400 K to ~710 K. This young, hot lava suggests that an episode of lava fountaining was underway. Since 2007, several eruptions have been seen in the Pillan region. The 18 February 2015 eruption was discovered during a mutual occultation event with the NASA IRTF. This event was (serendipitously) subsequently imaged with the Large Binocular Telescope Interferometer (LBTI) on 8 March 2015 during a mutual event occultation, and again with the IRTF on 15 March. The site was imaged with the Keck and Gemini-N telescopes between 27 March and May 5, during which time the intensity gradually decreased. Interestingly, the precise location of the eruption had shifted to the north-west from Pillan Patera, where the initial (18 Feb) eruption had taken place. In contrast to the episodicity of Pillan, Pele has been remarkably consistent in its thermal emission during the Galileo era [1] through February 2002, when a blackbody temperature of 940 ± 40 K and an area of 6.5 km2 was measured. Since that

  2. Formerly utilized MED/AEC sites remedial action program. Radiological survey of Universal Cyclopes, Inc., Titusville, Plant (formerly Vulcan Crucible Steel Company, Aliquippa, Pennsylvania, May 2-8, 1978)

    International Nuclear Information System (INIS)

    Wynveen, R.A.; Smith, W.H.; Mundis, R.L.; Mayes, C.B.

    1982-05-01

    A radiological survey was conducted at the Universal Cyclops, Inc. Titusville Plant (formerly Vulcan Crucible Steel Company), in Aliquippa, Pennsylvania, to determine the location and quantities of any radioactive materials remaining on the site as a result of MED/AEC activities in the late 1940s. This facility was used for rolling uranium billets during the MED/AEC era. The survey included measurements of alpha and beta-gamma contamination, both fixed and removable; beta-gamma exposure readings at contact and at 1 m (3 ft) above the floor or ground level; and measurements of the concentrations of radon daughters in air and concentrations of 137 Cs, the 232 Th decay chain, the 226 Ra decay chain, and uranium in the soil on the site. Fourteen spots of contamination exceeded the allowable limits for natural uranium. Under current use conditions, the potential for radiation exposure of occupants of the building from these sources of contamination is remote. Concentrations of radon daughters were below the 0.01 WL limit. Calculated radon concentrations based on the radon-daughter determinations ranged from 0.11 to 0.27 pCi/l. The concentration guide for 222 Rn in uncontrolled areas is 3 pCi/l. Analysis of soil samples from the site indicated elevated concentrations of uranium (15.1 +- 0.7 to 109.0 +- 5.5 pCi/g) at one sampling location near the building. There currently are no regulatory limits for uranium concentration in soil, but, a proposed guide value is pCi/g. After evaluation of results of the survey, it was concluded that although some areas of the Universal Cyclops facility are contaminated, these areas do not pose a significant risk to the present occupants of the building. Nonetheless, in a few cases the contamination does exceed accepted guidelines. Remedial measures are indicated to bring the contaminated areas within the guidelines

  3. EFEITO FUNGITÓXICO DO ÓLEO DE NIM SOBRE Metarhizium anisopliae var. acridum e Metarhizium anisopliae var. anisopliae

    Directory of Open Access Journals (Sweden)

    Álison Bruno da Silva Santos

    2009-01-01

    Full Text Available Plague control is based almost exclusively on application of chemical substances, however these products are toxic to men and animals and cause odd effects on environment quality. In Plague Integrated Management (PIM, the use of selected insecticides and entomopathogenic fungi should be considered as one viable strategy for plague control in agriculture. This work aimed to evaluate, in laboratory, the compatibility of the entomopathogenic fungi Metarhizium anisopliae var. acridum and Metarhizium anisopliae var. anisopliae with the oil of Nim. The addition of the product was made to the potato-dextrose-agar medium still liquid (±45°C, in a way that the final concentration obeyed 50% of the producer's recommendation. After fungi inoculation, the dishes were incubated in a cimatized room at 28°C, photophase of 12 hours and relative humidity of 75±5% for 12 day period. The number of conidia per colonie was counted with a Neubauer chamber. Statistic delineament was entirely in random, with two treatments (PDA with insecticide, and a control group (PDA without insecticide, and 9 repetitions for each treatment. The results showed that the insecticide inhibited conidial production in Metarhizium anisopliae var. anisopliae strains when compared to the control group. The diameter of Metarhizium anisopliae var. acridum colonies suffered significative reduction in its size, compared to control. The tested insecticide, in the concentration and formulation used, presented compatibility with the tested strains.

  4. One-step self-assembled nanomicelles for improving the oral bioavailability of nimodipine.

    Science.gov (United States)

    Luo, Jing-Wen; Zhang, Zhi-Rong; Gong, Tao; Fu, Yao

    2016-01-01

    Our study aimed to develop a self-assembled nanomicelle for oral administration of nimodipine (NIM) with poor water solubility. Using Solutol(®) HS15, the NIM-loaded self-assembled nanomicelles displayed a near-spherical morphology with a narrow size distribution of 12.57 ± 0.21 nm (polydispersity index =0.071 ± 0.011). Compared with Nimotop(®) (NIM tablets), the intestinal absorption of NIM from NIM nanomicelle in rats was improved by 3.13- and 2.25-fold in duodenum and jejunum at 1 hour after oral administration. The cellular transport of NIM nanomicelle in Caco-2 cell monolayers was significantly enhanced compared to that of Nimotop(®). Regarding the transport pathways, clathrin, lipid raft/caveolae, and macropinocytosis mediated the cell uptake of NIM nanomicelles, while P-glycoprotein and endoplasmic reticulum/Golgi complex (ER/Golgi) pathways were involved in exocytosis. Pharmacokinetic studies in our research laboratory have showed that the area under the plasma concentration-time curve (AUC0-∞) of NIM nanomicelles was 3.72-fold that of Nimotop(®) via oral administration in rats. Moreover, the NIM concentration in the brain from NIM nanomicelles was dramatically improved. Therefore, Solutol(®) HS15-based self-assembled nanomicelles represent a promising delivery system to enhance the oral bioavailability of NIM.

  5. Atividade da torta de nim sobre adultos do cascudinho dos aviários em condições de laboratório Activity of neem cake on adults of the lesser mealworm in laboratory

    Directory of Open Access Journals (Sweden)

    Victor Michelon Alves

    2012-05-01

    Full Text Available O cascudinho dos aviários é considerado um importante problema mundial no sistema de produção avícola, por infestar os aviários e ser potencial vetor de patógenos às aves e ao ser humano. O objetivo do trabalho foi avaliar em laboratório a atividade da torta de nim, Azadirachta indica A. Juss (Meliaceae como forma alternativa de controle de Alphitobius diaperinus Panzer (Coleoptera: Tenebrionidae. A torta foi aplicada diretamente no substrato (ração para aves ou cama de aviário na quantidade de 100g m-2 do produto. Foram verificados os efeitos letais e subletais da torta contra adultos do cascudinho dos aviários, sendo eles: ação inseticida, efeito na oviposição, repelência e efeito na alimentação. A utilização de torta de nim pareceu não afetar a sobrevivência dos insetos, porém, a avaliação do efeito repelente, atividade alimentar e oviposição foram influenciados, sendo observada redução de 23% na oviposição e 21% na atividade alimentar.The lesser mealworm is one the most important problem to avian production system, being a potential vector of avian and other animal pathogens. The objective of this study was to evaluate the neem cake (Azadirachta indica A. Juss (Meliaceae as an alternative to control the Alphitobius diaperinus Panzer (Coleoptera: Tenebrionidae. The neem cake was directly applied to substrates at 100g m-2 and were evaluated the lethal and sublethal effects to A. diaperinus adults, as mortality, oviposition, repellent effect and feeding. There was no effect on adult mortality, but were observed reduction of the oviposition (23%, repellent effect, and reduction of insect feeding (21%.

  6. Charting thermal emission variability at Pele, Janus Patera and Kanehekili Fluctus with the Galileo NIMS Io Thermal Emission Database (NITED)

    Science.gov (United States)

    Davies, Ashley Gerard; Veeder, Glenn J.; Matson, Dennis L.; Johnson, Torrence V.

    2012-09-01

    Using the NIMS Io Thermal Emission Database (NITED), a collection of over 1000 measurements of radiant flux from Io’s volcanoes (Davies, A.G. et al. [2012]. Geophys. Res. Lett. 39, L01201. doi:10.1029/2011GL049999), we have examined the variability of thermal emission from three of Io’s volcanoes: Pele, Janus Patera and Kanehekili Fluctus. At Pele, the 5-μm thermal emission as derived from 28 night time observations is remarkably steady at 37 ± 10 GW μm-1, re-affirming previous analyses that suggested that Pele an active, rapidly overturning silicate lava lake. Janus Patera also exhibits relatively steady 5-μm thermal emission (≈20 ± 3 GW μm-1) in the four observations where Janus is resolved from nearby Kanehekili Fluctus. Janus Patera might contain a Pele-like lava lake with an effusion rate (QF) of ≈40-70 m3 s-1. It should be a prime target for a future mission to Io in order to obtain data to determine lava eruption temperature. Kanehekili Fluctus has a thermal emission spectrum that is indicative of the emplacement of lava flows with insulated crusts. Effusion rate at Kanehekili Fluctus dropped by an order of magnitude from ≈95 m3 s-1 in mid-1997 to ≈4 m3 s-1 in late 2001.

  7. Diagramas de equilibrio para la extracción con solvente de aceite e insecticida de semilla molida de nim

    Directory of Open Access Journals (Sweden)

    R. Espinosa

    2006-01-01

    Full Text Available En este trabajo se construyeron diagramas de equilibrio para la extracción con hexano de aceite de la semilla molida de nim (GNSK y de la extracción posterior con etanol de insecticida de la GNSK sin aceite. Los datos experimentales fueron obtenidos a diferentes temperaturas, poniendo en contacto sólido y solvente en diferentes proporciones en frascos Erlenmeyer. Se suministró agitación y se mantuvo la temperatura controlada hasta alcanzar el equilibrio. La composición del extracto y del refinado se determinó separando los solventes por evaporación. Se propone ecuaciones para la curva de refinado y la curva de distribución. En ambas extracciones, la fracción de solución retenida dentro de la estructura celular del sólido molido aumenta con la temperatura. La concentración del extracto tiene más influencia en la cantidad de solución retenida para la extracción de insecticida que para la extracción de aceite. Para extractos diluidos, la concentración de soluto tiende a ser mayor en el extracto que en la solución retenida. Esta tendencia es más pronunciada cuando la temperatura aumenta. A temperaturas cercanas al punto de ebullición, hay mayor tendencia a la retención de solvente por el sólido, a cualquier concentración.

  8. A NIM (Nuclear Instrumentation Module) system conjugated with optional input for pHEMT amplifier for beta and gamma spectroscopy

    International Nuclear Information System (INIS)

    Konrad, Barbara; Lüdke, Everton

    2014-01-01

    This work presents a high speed NIM module (Nuclear Instrumentation Module) to detect radiation, gamma and muons, as part of a system for natural radiation monitoring and of extraterrestrial origin. The subsystem developed consists of a preamplifier and an integrated SCA (Single Channel Analyzer), including power supplies of ± 12 and ± 24V with derivations of +3.6 and ± 5V. The single channel analyzer board, consisting of discrete logic components, operating in window modes, normal and integral. The pulse shaping block is made up of two voltage comparators working at 120 MHz with a response time > 60 ns and a logic anticoincidence system. The preamplifier promotes a noise reduction and introduces the impedance matching between the output of anode / diode photomultiplier tubes (PMTs) and subsequent equipment, providing an input impedance of 1MΩ and output impedance of 40 to 140Ω. The shaper amplifier is non-inverting and has variable input capacitance of 1000 pF. The upper and lower thresholds of the SCA are adjustable from 0 to ± 10V, and the equipment is compatible with various types of detectors, like PMTs coupled to sodium iodide crystals. For use with liquid scintillators and photodiodes with crystals (CsI: Tl) is proposed to include a preamplifier circuit pHEMT (pseudomorphic High Electron Mobility Transistor) integrated. Yet, the system presents the possibility of applications for various purposes of gamma spectroscopy and automatic detection of events producing of beta particles

  9. Index to the 1st through 16th AEC/ERDA/DOE nuclear air cleaning conferences

    International Nuclear Information System (INIS)

    Burchsted, C.A.

    1981-02-01

    The Proceedings of the sixteen conferences comprise a vertible encyclopedia on the technology of nuclear air and gas treatment and the control of airborne nuclear waste. These Proceedings cover the history of the technology; describe most of the research and developments in the field, worldwide, since the early 1950's; describe the problems that have been encountered and the solutions found to those problems; and summarize experience with equipment and systems developed for the control of airborne radioactive wastes in laboratory, radiochemical, and reactor operations, both government and commercial. The problem with this encyclopedia is that there has been no index to it; there has been no easy way for searching it to find what was available. This index fills the gap. The first conference was an informal meeting of a number of interested parties from among the then AEC contractors. Consequently, there were no proceedings for that meeting. The subsequent conferences, with their years, locations, and Proceedings numbers, are listed. This index consists of three parts: a tabulation of papers and their authors by paper number (Part I); a tabulation of papers and their paper numbers by author (Part II); and a key-word-in context (KWIC) index of papers. The paper number is a two-part designation consisting of the number of the conference (2, 3...16) followed by the page number of the paper in the corresponding Proceedings. The author index lists each author who has participated in the air cleaning conferences over the years, and the paper index lists all authors of the respective papers. The KWIC index is, in effect, a comprehensive subject cross index; each paper is listed as many times, by keyword, as there are major terms (i.e., keywords) in its title. Although this multiple listing results in a lengthy list, it provides a very deep cross-indexing of the papers

  10. One-step self-assembled nanomicelles for improving the oral bioavailability of nimodipine

    Directory of Open Access Journals (Sweden)

    Luo JW

    2016-03-01

    Full Text Available Jing-Wen Luo, Zhi-Rong Zhang, Tao Gong, Yao Fu Key Laboratory of Drug Targeting and Drug Delivery Systems, Ministry of Education, West China School of Pharmacy, Sichuan University, Chengdu, Sichuan, People’s Republic of China Abstract: Our study aimed to develop a self-assembled nanomicelle for oral administration of nimodipine (NIM with poor water solubility. Using Solutol® HS15, the NIM-loaded self-assembled nanomicelles displayed a near-spherical morphology with a narrow size distribution of 12.57±0.21 nm (polydispersity index =0.071±0.011. Compared with Nimotop® (NIM tablets, the intestinal absorption of NIM from NIM nanomicelle in rats was improved by 3.13- and 2.25-fold in duodenum and jejunum at 1 hour after oral administration. The cellular transport of NIM nanomicelle in Caco-2 cell monolayers was significantly enhanced compared to that of Nimotop®. Regarding the transport pathways, clathrin, lipid raft/caveolae, and macropinocytosis mediated the cell uptake of NIM nanomicelles, while P-glycoprotein and endoplasmic reticulum/Golgi complex (ER/Golgi pathways were involved in exocytosis. Pharmacokinetic studies in our research laboratory have showed that the area under the plasma concentration–time curve (AUC0–∞ of NIM nanomicelles was 3.72-fold that of Nimotop® via oral administration in rats. Moreover, the NIM concentration in the brain from NIM nanomicelles was dramatically improved. Therefore, Solutol® HS15-based self-assembled nanomicelles represent a promising delivery system to enhance the oral bioavailability of NIM. Keywords: nanomicelles, stability, nimodipine, oral bioavailability, transport mechanism 

  11. Efeitos do nim sobre tetranychus urticae Koch (Acari: Tetranychidae e os predadores Phytoseiulus macropilis (Banks e Neoseiulus californicus (Mcgregor (Acari: Phytoseiidae

    Directory of Open Access Journals (Sweden)

    Daniele Cristine Hoffmann Schlesener

    2013-03-01

    Full Text Available O objetivo deste trabalho foi avaliar a eficiência de controle e os efeitos adversos de dois produtos à base de nim Azamax® (Azadiractina A/B 12g/L e Neemseto® (Azadiractina A/B, Nimbina e Salanina 2,389 g/L sobre o ácaro-rajado Tetranychus urticae e os predadores Phytoseiulus macropilis e Neoseiulus californicus em laboratório. Para o ácaro-rajado, foram consideradas as variáveis mortalidade, fecundidade, efeito ovicida e persistência biológica, enquanto para os fitoseídeos consideraram-se mortalidade e fecundidade. A mortalidade máxima observada para o ácaro-rajado foi de 89,7% e 91,5% para Azamax® e Neemseto®, respectivamente, na concentração de 0,5% após a reaplicação do produto no sétimo dia. Também foram observados efeitos adversos sobre a fecundidade e a viabilidade dos ovos quando tratados com os produtos comerciais (p.c.. A persistência biológica dos produtos foi de aproximadamente três dias após a pulverização. As formulações apresentaram seletividade em relação aos fitoseídeos, porém causaram redução da fecundidade dos mesmos.

  12. Developing institutional repository at National Institute for Materials Science : Researchers directory service “SAMURAI” and Research Collection Library

    Science.gov (United States)

    Takaku, Masao; Tanifuji, Mikiko

    National Institute for Materials Science (NIMS) has developed an institutional repository “NIMS eSciDoc” since 2008. eSciDoc is an open source repository software made in Germany, and provides E-Science infrastructures through its flexible data model and rich Web APIs. NIMS eScidoc makes use of eSciDoc functions to benefit for NIMS situations. This article also focuses on researchers directory service “SAMURAI” in addition to NIMS eSciDoc. Successfully launched in October 2010, SAMURAI provides approximately 500 researchers' profile and publication information.

  13. Synthesis and evaluation of mesoporous carbon/lipid bilayer nanocomposites for improved oral delivery of the poorly water-soluble drug, nimodipine.

    Science.gov (United States)

    Zhang, Yanzhuo; Zhao, Qinfu; Zhu, Wufu; Zhang, Lihua; Han, Jin; Lin, Qisi; Ai, Fengwei

    2015-07-01

    A novel mesoporous carbon/lipid bilayer nanocomposite (MCLN) with a core-shell structure was synthesized and characterized as an oral drug delivery system for poorly water-soluble drugs. The objective of this study was to investigate the potential of MCLN-based formulation to modulate the in vitro release and in vivo absorption of a model drug, nimodipine (NIM). NIM-loaded MCLN was prepared by a procedure involving a combination of thin-film hydration and lyophilization. Scanning electron microscopy (SEM), transmission electron microscopy (TEM), specific surface area analysis, differential scanning calorimetry (DSC) and X-ray diffraction (XRD) were employed to characterize the NIM-loaded MCLN formulation. The effect of MCLN on cell viability was assessed using the MTT assay. In addition, the oral bioavailability of NIM-loaded MCLN in beagle dogs was compared with that of the immediate-release formulation, Nimotop®. Our results demonstrate that the NIM-loaded MCLN formulation exhibited a typical sustained release pattern. The NIM-loaded MCLN formulation achieved a greater degree of absorption and longer lasting plasma drug levels compared with the commercial formulation. The relative bioavailability of NIM for NIM-loaded MCLN was 214%. MCLN exhibited negligible toxicity. The data reported herein suggest that the MCLN matrix is a promising carrier for controlling the drug release rate and improving the oral absorption of poorly water-soluble drugs.

  14. Muusikamaailm : "Let the Peoples Sing 1999". Bruckneri päevad Viinis. Festival Huddersfieldis. Kolmelt pianistide konkursilt / Priit Kuusk

    Index Scriptorium Estoniae

    Kuusk, Priit, 1938-

    1999-01-01

    Rahvusvahelise raadiokonkursi "Let the Peoples Sing" võitjatest. A. Bruckneri 175. sünniaastapäeva puhul toimunud Bruckneri päevadest Viinis. Kaasaegse muusika festivalist Huddersfieldist. Pianistide konkurssidest - Dino Ciani nim. konkursist Milanos, 7. Schuberti-nim. konkursist Dortmundis ja Ferruccio Busoni nim. konkursist Itaalias Bolzanos

  15. Maakondade rahvakultuuri aastapreemiad 2001

    Index Scriptorium Estoniae

    2002-01-01

    Fr. R. Kreutzwaldi nim mälestusmedali ja Kreutzwaldi-stipendiumi statuudid, lk. 89-00. Hendrik Lindepuu sai Jõgevamaa kirjanduspreemia; Mari Vallisoo sai Juhan Liivi nim. luuleauhinna, Elle-Eha Are sai Viljandimaa kultuuripreemia ja Contra B. Kangro nim. kirjanduspreemia. F. R. Kreutzwaldi mälestusmedali sai Aarand Roos

  16. Toxicidade aguda do sulfato de cobre e do extrato aquoso de folhas secas de nim para o caramujo (Pomacea canaliculata = Acute toxicity of copper sulfate and aqueous extract of dried neem leaves on snails (Pomacea canaliculata

    Directory of Open Access Journals (Sweden)

    Francine Perri Venturini

    2008-04-01

    Full Text Available Os caramujos podem se tornar um problema ambiental e econômico, podendo causar muitos prejuízos. O trabalho teve como objetivo estimar a toxicidade aguda do sulfato de cobre pentaidratado (CuSO4.5H2O e do extrato aquoso de folhas secas de nim para o P. canaliculata, em condição de laboratório. Para determinação da CL (I(50;96h, o caramujo foi exposto a seis concentrações crescentes de sulfato de cobre (0,0; 0,01; 0,03; 0,05; 0,07 e 0,1 mg L-1 e a seis concentrações crescentes de extrato aquoso de folhas secas denim (0,0; 100; 125; 150; 175 e 200 mL de extrato aquoso de folhas secas de nim L-1 de água, equivalente a 0,0; 1,18; 1,47; 1,77; 2,06; e 2,36 mg de azadiractina L-1, com três repetições e um tratamento-controle em um experimento no delineamento inteiramente casualizado(DIC. A CL (I(50;96h estimada para o caramujo foi de 0,07 mg de sulfato de cobre L-1, com limite inferior de 0,05 mg L-1 e limite superior de 0,1 mg L-1. A concentração letal 50% (CL (I50;96h estimada do extrato aquoso de folhas secas de nim (EAFSN para o caramujo foi de 142,75 mL L-1, equivalente a 1,68 mg L-1 de azadiractina, com limite inferior de 130,89 mL L-1 (1,54, mg L-1 e limite superior de 155,69 mL L-1 (1,83 mg L-1.Snails can become an environmental and economic problem, causing substantial losses. The objective of this work was to estimatethe acute toxicity of copper sulfate pentahydrate (CuSO4.5H2O and the aqueous extract of dried neem leaves on snails (P. canaliculata under laboratory conditions. In order to estimate the lethal concentration 50% (LC (I50;96h, snails were exposed to six increasing copper sulfate concentrations (0.0; 0.01; 0.03; 0.05; 0.07 and 0.1 mg L-1 and six increasing concentrations of aqueous extract of dried neem leaves 0.0; 100; 125; 150; 175 and 200 mL aqueous extract of dried neem leaves L-1 water, equivalent to (0.0; 1.18; 1.47; 1.77; 2.06; and 2.36 mg azadirachtin L-1, in triplicate and one control treatment in an

  17. The Synergy Effect of Ni-M (M = Mo, Fe, Co, Mn or Cr Bicomponent Catalysts on Partial Methanation Coupling with Water Gas Shift under Low H2/CO Conditions

    Directory of Open Access Journals (Sweden)

    Xinxin Dong

    2017-02-01

    Full Text Available Ni-M (M = Mo, Fe, Co, Mn or Cr bicomponent catalysts were prepared through the co-impregnation method for upgrading low H2/CO ratio biomass gas into urban gas through partial methanation coupling with water gas shift (WGS. The catalysts were characterized by N2 isothermal adsorption, X-ray diffraction (XRD, H2 temperature programmed reduction (H2-TPR, H2 temperature programmed desorption (H2-TPD, scanning electron microscopy (SEM and thermogravimetry (TG. The catalytic performances demonstrated that Mn and Cr were superior to the other three elements due to the increased fraction of reducible NiO particles, promoted dispersion of Ni nanoparticles and enhanced H2 chemisorption ability. The comparative study on Mn and Cr showed that Mn was more suitable due to its smaller carbon deposition rate and wider adaptability to various H2/CO and H2O/CO conditions, indicating its better synergy effect with Ni. A nearly 100 h, the lifetime test and start/stop cycle test further implied that 15Ni-3Mn was stable for industrial application.

  18. Ressenya a Delle Donne, Fulvio & Torró, Jaume (eds. L’immagine di Alfonso il Magnanimo tra letteratura e storia, tra Corona d’Aragona e Italia - La imatge d’Algons el Magnànim en la literatura i la Historiografia entre la Corona d’Aragó i Itàlia, Florència, SISMEL -Edizioni del Galluzzo , 2016, XII + 300 p. ISBN: 978-88-8450-691-7

    Directory of Open Access Journals (Sweden)

    Marta Marfany Simó

    2016-12-01

    Full Text Available Review to Delle Donne, Fulvio & Torró, Jaume (eds. L’immagine di Alfonso il Magnanimo tra letteratura e storia, tra Corona d’Aragona e Italia - La imatge d’Algons el Magnànim en la literatura i la Historiografia entre la Corona d’Aragó i Itàlia, Firenze, SISMEL -Edizioni del Galluzzo , 2016, XII + 300 p. ISBN: 978-88-8450-691-7

  19. Toxicidade aguda do sulfato de cobre e do extrato aquoso de folhas secas de nim para o caramujo (Pomacea canaliculata - DOI: 10.4025/actascibiolsci.v30i2.3615 Acute toxicity of copper sulfate and aqueous extract of dried neem leaves on snails (Pomacea canaliculata - DOI: 10.4025/actascibiolsci.v30i3.3615

    Directory of Open Access Journals (Sweden)

    Robinson Antonio Pitelli

    2008-05-01

    Full Text Available Os caramujos podem se tornar um problema ambiental e econômico, podendo causar muitos prejuízos. O trabalho teve como objetivo estimar a toxicidade aguda do sulfato de cobre pentaidratado (CuSO4.5H2O e do extrato aquoso de folhas secas de nim para o P. canaliculata, em condição de laboratório. Para determinação da CL (I(50;96h, o caramujo foi exposto a seis concentrações crescentes de sulfato de cobre (0,0; 0,01; 0,03; 0,05; 0,07 e 0,1 mg L-1 e a seis concentrações crescentes de extrato aquoso de folhas secas de nim (0,0; 100; 125; 150; 175 e 200 mL de extrato aquoso de folhas secas de nim L-1 de água, equivalente a 0,0; 1,18; 1,47; 1,77; 2,06; e 2,36 mg de azadiractina L-1, com três repetições e um tratamento-controle em um experimento no delineamento inteiramente casualizado (DIC. A CL (I(50;96h estimada para o caramujo foi de 0,07 mg de sulfato de cobre L-1, com limite inferior de 0,05 mg L-1 e limite superior de 0,1 mg L-1. A concentração letal 50% (CL (I50;96h estimada do extrato aquoso de folhas secas de nim (EAFSN para o caramujo foi de 142,75 mL L-1, equivalente a 1,68 mg L-1 de azadiractina, com limite inferior de 130,89 mL L-1 (1,54, mg L-1 e limite superior de 155,69 mL L-1 (1,83 mg L-1.Snails can become an environmental and economic problem, causing substantial losses. The objective of this work was to estimate the acute toxicity of copper sulfate pentahydrate (CuSO4.5H2O and the aqueous extract of dried neem leaves on snails (P. canaliculata under laboratory conditions. In order to estimate the lethal concentration 50% (LC (I50;96h, snails were exposed to six increasing copper sulfate concentrations (0.0; 0.01; 0.03; 0.05; 0.07 and 0.1 mg L-1 and six increasing concentrations of aqueous extract of dried neem leaves 0.0; 100; 125; 150; 175 and 200 mL aqueous extract of dried neem leaves L-1 water, equivalent to (0.0; 1.18; 1.47; 1.77; 2.06; and 2.36 mg azadirachtin L-1, in triplicate and one control treatment in an

  20. The Relationship between a New Biomarker of Vagal Neuroimmunomodulation and Survival in Two Fatal Cancers

    Directory of Open Access Journals (Sweden)

    Y. Gidron

    2018-01-01

    Full Text Available Background. The vagus nerve may slow tumor progression because it inhibits inflammation. This study examined the relationship between a new vagal neuroimmunomodulation (NIM index and survival in fatal cancers. Method. We retroactively derived markers of vagal nerve activity indexed by heart rate variability (HRV, specifically the root mean square of successive differences (RMSSD, from patients’ electrocardiograms near diagnosis. The NIM index was the ratio of RMSSD to C-reactive protein levels (RMSSD/CRP. Sample 1 included 202 Belgian patients with advanced pancreatic cancer (PC, while sample 2 included 71 Belgian patients with non-small cell lung cancer (NSCLC. In both samples, we examined the overall survival, while in sample 2, we additionally examined the survival time in deceased patients. Results. In PC patients, in a multivariate Cox regression controlling for confounders, the NIM index had a protective relative risk (RR of 0.68 and 95% confidence interval (95% CI of 0.51–0.92. In NSCLC patients, the NIM index also had a protective RR of 0.53 and 95% CI of 0.32–0.88. Finally, in NSCLC, patients with a higher NIM index survived more days (475.2 than those with lower NIM (285.1 (p<0.05. Conclusions. The NIM index, reflecting vagal modulation of inflammation, may be a new independent prognostic biomarker in fatal cancers.

  1. Bulk and Thin film Properties of Nanoparticle-based Ionic Materials

    Science.gov (United States)

    Fang, Jason

    2008-03-01

    Nanoparticle-based ionic materials (NIMS) offer exciting opportunities for research at the forefront of science and engineering. NIMS are hybrid particles comprised of a charged oligomeric corona attached to hard, inorganic nanoparticle cores. Because of their hybrid nature, physical properties --rheological, optical, electrical, thermal - of NIMS can be tailored over an unusually wide range by varying geometric and chemical characteristics of the core and canopy and thermodynamic variables such as temperature and volume fraction. On one end of the spectrum are materials with a high core content, which display properties similar to crystalline solids, stiff waxes, and gels. At the opposite extreme are systems that spontaneously form particle-based fluids characterized by transport properties remarkably similar to simple liquids. In this poster I will present our efforts to synthesize NIMS and discuss their bulk and surface properties. In particular I will discuss our work on preparing smart surfaces using NIMS.

  2. Canopy Dynamics in Nanoscale Ionic Materials Probed by NMR

    Science.gov (United States)

    Mirau, Peter

    2013-03-01

    Nanoscale ionic materials (NIMs) are hybrids prepared from ionically functionalized nanoparticles (NP) neutralized by oligomeric polymer counter-ions. NIMs are designed to behave as liquids under ambient conditions in the absence of solvent and have no volatile organic content, making them useful for a number of applications. We have used NMR relaxation and pulse-field gradient NMR to probe local and collective canopy dynamics in NIMs based on silica nanoparticles (NP), fullerols and proteins in order to understand the relationship between the core and canopy structure and the bulk properties. The NMR studies show that the canopy dynamics depend on the degree of neutralization, the canopy radius of gyration and molecular crowding at the ionically modified NP surface. The viscosity in NIMs can be directly controlled with the addition of ions that enhance the exchange rate for polymers at the NP surface. These results show that NIMs for many applications can be prepared by controlling the dynamics of the NP interface.

  3. Nuclear Magnetic Resonance Study of Nanoscale Ionic Materials

    KAUST Repository

    Oommen, Joanna Mary

    2010-08-13

    Nanoscale ionic materials (NIMs) are a new class of nanomaterials that exhibit interesting properties including negligible vapor pressures and tunable physical states, among others. In this study, we analyzed the temperature-wise performance of NIMs using nuclear magnetic resonance (NMR) spectroscopy. NIMs are relatively stable over a temperature range from 300 to 383 K, rendering them usable in high temperature applications. We confirmed the presence of covalent bonds between the SiO2 core and the sulfonate group and determined relative concentrations of aromatic and aliphatic hydrocarbons. These findings serve as first hand proof-of-concept for the usefulness of NMR analyses in further studies on the diffusive properties of NIMs. © 2010 The Electrochemical Society.

  4. Canopy Dynamics in Nanoscale Ionic Materials

    KAUST Repository

    Jespersen, Michael L.

    2010-07-27

    Nanoscale ionic materials (NIMS) are organic - inorganic hybrids in which a core nanostructure is functionalized with a covalently attached corona and an ionically tethered organic canopy. NIMS are engineered to be liquids under ambient conditions in the absence of solvent and are of interest for a variety of applications. We have used nuclear magnetic resonance (NMR) relaxation and pulse-field gradient (PFG) diffusion experiments to measure the canopy dynamics of NIMS prepared from 18-nm silica cores modified by an alkylsilane monolayer possessing terminal sulfonic acid functionality, paired with an amine-terminated ethylene oxide/propylene oxide block copolymer canopy. Carbon NMR studies show that the block copolymer canopy is mobile both in the bulk and in the NIMS and that the fast (ns) dynamics are insensitive to the presence of the silica nanoparticles. Canopy diffusion in the NIMS is slowed relative to the neat canopy, but not to the degree predicted from the diffusion of hard-sphere particles. Canopy diffusion is not restricted to the surface of the nanoparticles and shows unexpected behavior upon addition of excess canopy. Taken together, these data indicate that the liquid-like behavior in NIMS is due to rapid exchange of the block copolymer canopy between the ionically modified nanoparticles. © 2010 American Chemical Society.

  5. Canopy Dynamics in Nanoscale Ionic Materials

    KAUST Repository

    Jespersen, Michael L.; Mirau, Peter A.; Meerwall, Ernst von; Vaia, Richard A.; Rodriguez, Robert; Giannelis, Emmanuel P.

    2010-01-01

    Nanoscale ionic materials (NIMS) are organic - inorganic hybrids in which a core nanostructure is functionalized with a covalently attached corona and an ionically tethered organic canopy. NIMS are engineered to be liquids under ambient conditions in the absence of solvent and are of interest for a variety of applications. We have used nuclear magnetic resonance (NMR) relaxation and pulse-field gradient (PFG) diffusion experiments to measure the canopy dynamics of NIMS prepared from 18-nm silica cores modified by an alkylsilane monolayer possessing terminal sulfonic acid functionality, paired with an amine-terminated ethylene oxide/propylene oxide block copolymer canopy. Carbon NMR studies show that the block copolymer canopy is mobile both in the bulk and in the NIMS and that the fast (ns) dynamics are insensitive to the presence of the silica nanoparticles. Canopy diffusion in the NIMS is slowed relative to the neat canopy, but not to the degree predicted from the diffusion of hard-sphere particles. Canopy diffusion is not restricted to the surface of the nanoparticles and shows unexpected behavior upon addition of excess canopy. Taken together, these data indicate that the liquid-like behavior in NIMS is due to rapid exchange of the block copolymer canopy between the ionically modified nanoparticles. © 2010 American Chemical Society.

  6. Estudio de las escenas: Jesús es condedado a muerte y Jesús ante Poncio Pilato, del conjunto pictórico de la iglesia del Santísimo Cristo de Benigànim. Estado de conservación, propuesta de intervención y presupuesto económico de restauración.

    OpenAIRE

    LLOPIS SERRANO, PAULA

    2015-01-01

    Este trabajo final de grado expone el estudio técnico, del estado de conservación, la propuesta de intervención, y el presupuesto de restauración de les dos escenas pertenecientes al conjunto pictórico de la Iglesia del Santísimo Cristo de Benigpànim. El estudio prevé un enfoque, tanto documental como analítico, determinando la técnica pictórica, el estado de conservación en el que se encuentra, y las posibles intervenciones anteriores. This final course work explains the technical work...

  7. Computational methods and modeling. 3. Adaptive Mesh Refinement for the Nodal Integral Method and Application to the Convection-Diffusion Equation

    International Nuclear Information System (INIS)

    Torej, Allen J.; Rizwan-Uddin

    2001-01-01

    The nodal integral method (NIM) has been developed for several problems, including the Navier-Stokes equations, the convection-diffusion equation, and the multigroup neutron diffusion equations. The coarse-mesh efficiency of the NIM is not fully realized in problems characterized by a wide range of spatial scales. However, the combination of adaptive mesh refinement (AMR) capability with the NIM can recover the coarse mesh efficiency by allowing high degrees of resolution in specific localized areas where it is needed and by using a lower resolution everywhere else. Furthermore, certain features of the NIM can be fruitfully exploited in the application of the AMR process. In this paper, we outline a general approach to couple nodal schemes with AMR and then apply it to the convection-diffusion (energy) equation. The development of the NIM with AMR capability (NIMAMR) is based on the well-known Berger-Oliger method for structured AMR. In general, the main components of all AMR schemes are 1. the solver; 2. the level-grid hierarchy; 3. the selection algorithm; 4. the communication procedures; 5. the governing algorithm. The first component, the solver, consists of the numerical scheme for the governing partial differential equations and the algorithm used to solve the resulting system of discrete algebraic equations. In the case of the NIM-AMR, the solver is the iterative approach to the solution of the set of discrete equations obtained by applying the NIM. Furthermore, in the NIM-AMR, the level-grid hierarchy (the second component) is based on the Hierarchical Adaptive Mesh Refinement (HAMR) system,6 and hence, the details of the hierarchy are omitted here. In the selection algorithm, regions of the domain that require mesh refinement are identified. The criterion to select regions for mesh refinement can be based on the magnitude of the gradient or on the Richardson truncation error estimate. Although an excellent choice for the selection criterion, the Richardson

  8. Options for radiation dose optimisation in pelvic digital radiography: A phantom study

    International Nuclear Information System (INIS)

    Manning-Stanley, Anthony S.; Ward, Anthony J.; England, Andrew

    2012-01-01

    Purpose: To investigate the effects of phantom orientation and AEC chamber selection on radiation dose and image quality (IQ) for digital radiography (DR) examinations of the pelvis. Methods: A phantom study was conducted using a DR detector, utilising all AEC chamber combinations. Current recommended orientation (Cr-AEC) was with the outer AEC chambers cranially orientated. mAs (given), source-to-skin distance and kV p data facilitated entrance surface dose and effective dose calculations. Six anatomical areas were blindly graded by two observers (3-point scale) for IQ. Statistical differences in radiation dose were determined using the paired Student’s t-test. IQ data was analysed for inter-observer variability (ICC) and statistical differences (Wilcoxon test). Results: Switching phantom orientation (caudally orientated outer AEC chambers: Ca-AEC) reduced mean radiation dose by 36.8%, (p < 0.001). A minor reduction in median IQ (15.5 vs. 15) was seen (p < 0.001). One Ca-AEC orientated image (1.6%) had all anatomical areas graded ‘inadequate’ by at least one observer; all other images were considered ‘adequate’ for all areas. In the Ca-AEC orientation, at least a 44% dose reduction was achievable (p < 0.001) when only the outer AEC chambers were used. In the Cr-AEC orientation, at least 11% dose reduction was achieved (p < 0.001); here the central chamber was used alone, or in combination. IQ scores fell, but remained ‘adequate’. Conclusion: Switching pelvic orientation relative to AEC chamber position can optimise radiation dose during pelvic radiography. AEC chamber position should be clearly marked on equipment to facilitate this. AEC selection should be an active process.

  9. Physical protection of plutonium in USA

    International Nuclear Information System (INIS)

    Kaseda, Noboru

    1974-01-01

    The present situation of nuclear substance protection in USA is introduced for reference sake. The protection regulation has been revised since 1973 as follows: the protection plan once approved by AEC shall not be modified without the prior approval by AEC; AEC shall inspect the execution of the approved protection plan by measuring and testing nuclear substances and related equipments, and by checking the records of retention, use and transportation of nuclear substances; in the event of finding some imperfection, those concerned with the facilities shall improve the imperfection, and shall report the results to AEC: in the event of danger of theft or obstruction, report shall be made to AEC, and AEC shall contact with FBI, custom bureau, coast guard or CIA according to the matter. The requisites of AEC are briefly described. For atomic power plants, AEC has not prescribed requirements, but regulates by tentative system. In transportation, the protection requirements of AEC are applied to the cases of 2 kg or more Pu and 5 kg or more U-235 in 20% or more enriched U, and the regulations for road, rail, sea and air transport are prescribed separately. AEC has published a regulation guide concerning ten fields, e.g. power reactor, research reactor, fuel processing facility and environment. Although AEC has strengthened the protection system, several documents have been published and aroused argument, which forced AEC to examine them. Two documents are introduced. One is ''Profiles - the curve of binding energy'' published in the ''New Yorker'' in 1973, and the other is ''Nuclear theft: risks and safeguards'', published in 1974. AEC staff evaluation report, GESMO report and others are outlined. (Iwakiri, K.)

  10. Detection of B. fragilis group and diversity of bft enterotoxin and antibiotic resistance markers cepA, cfiA and nim among intestinal Bacteroides fragilis strains in patients with inflammatory bowel disease.

    Science.gov (United States)

    Rashidan, Marjan; Azimirad, Masoumeh; Alebouyeh, Masoud; Ghobakhlou, Mehdi; Asadzadeh Aghdaei, Hamid; Zali, Mohammad Reza

    2018-04-01

    We compared frequency of the members of B. fragilis group in 100 and 20 colon biopsy specimens of inflammatory bowel disease (IBD) and non-IBD patients. Agar dilution and PCR were orderly used to detect minimal inhibitory concentration of ampicillin, imipenem, and metronidazole, and carriage of related resistance genes cepA, cfi, and nim. B. fragilis group was detected in 38% of IBD (UC: 36/89; CD:1/11) and 25% (5/20) of non-IBD patients. While B. vulgatus (UC: 20/36, CD: 1/2, control: 1/6); B. fragilis (UC: 18/36, CD: 1/2, control: 5/6); B. ovatus (UC: 2/36); B. caccae (UC: 1/36); and B. eggerthii (UC: 1/36) were characterized, colonization of B. thetaiotamicron, B. merdae, B. distasonis, B. stercoris and B. dorei species was not detected in these specimens. Co-existence of B. fragilis + B. vulgatus (5 patients) and B. vulgatus + B. caccae (1 patient) was detected just in UC patients. bft was detected among 31.5% (6/19) of B. fragilis strains in the IBD and 40% (2/5) in the non-IBD groups. Nearly, 73.6% of the strains from the patient group and 80% in control group harbored cepA; 31.5% and 20% in the patients and control groups harbored cfiA, and none of them harbored nim determinant. Co-occurrence of the cepA and cfiA was orderly detected in 10.5% (2/19) and 20% (1/5) of the strains in these groups. The resistance rates were detected as 95.8% (23/24 (to ampicillin (MIC range of ≤0.5-≥16 μg/ml), 0% to metronidazole and 29.1% to imipenem (7/24, MIC range ≤4-32 μg/ml). Nearly 25% (6/24) of the strains were resistant to ampicillin and imipenem, simultaneously. No statistically significant difference was detected between the IBD and control groups for drug resistance phenotypes. Statistical analysis showed significant associations between resistance to ampicillin or imipenem and carriage of cepA or cfiA, respectively (p value = 0.0007). PCR results on the extracted plasmids confirmed their roles in carriage of cfiA and cepA. These

  11. Positive effects of bFGF modified rat amniotic epithelial cells transplantation on transected rat optic nerve.

    Directory of Open Access Journals (Sweden)

    Jia-Xin Xie

    Full Text Available Effective therapy for visual loss caused by optic nerve injury or diseases has not been achieved even though the optic nerve has the regeneration potential after injury. This study was designed to modify amniotic epithelial cells (AECs with basic fibroblast growth factor (bFGF gene, preliminarily investigating its effect on transected optic nerve.A human bFGF gene segment was delivered into rat AECs (AECs/hbFGF by lentiviral vector, and the gene expression was examined by RT-PCR and ELISA. The AECs/hbFGF and untransfected rat AECs were transplanted into the transected site of the rat optic nerve. At 28 days post transplantation, the survival and migration of the transplanted cells was observed by tracking labeled cells; meanwhile retinal ganglion cells (RGCs were observed and counted by employing biotin dextran amine (BDA and Nissl staining. Furthermore, the expression of growth associated protein 43 (GAP-43 within the injury site was examined with immunohistochemical staining.The AECs/hbFGF was proven to express bFGF gene and secrete bFGF peptide. Both AECs/hbFGF and AECs could survive and migrate after transplantation. RGCs counting implicated that RGCs numbers of the cell transplantation groups were significantly higher than that of the control group, and the AECs/hbFGF group was significantly higher than that of the AECs group. Moreover GAP-43 integral optical density value in the control group was significantly lower than that of the cell transplantation groups, and the value in the AECs/hbFGF group was significantly higher than that of the AECs group.AECs modified with bFGF could reduce RGCs loss and promote expression of GAP-43 in the rat optic nerve transected model, facilitating the process of neural restoration following injury.

  12. Hydrogen embrittlement property of a 1700-MPa-class ultrahigh-strength tempered martensitic steel

    Energy Technology Data Exchange (ETDEWEB)

    Li Songjie; Zhang Boping [School of Materials Science and Engineering, University of Science and Technology Beijing, No. 30 Xueyuan Road, Hidian Zone, Beijing 100083 (China); Akiyama, Eiji; Yuuji, Kimura; Tsuzaki, Kaneaki [Structural Metals Center, National Institute for Materials Science, 1-2-1 Sengen, Tsukuba, Ibaraki 305-0047 (Japan); Uno, Nobuyoshi, E-mail: AKIYAMA.Eiji@nims.go.j [Nippon Steel and Sumikin Metal Products Co, Ltd, SA Bldg., 17-12 Kiba 2-chome, Koto-ku, Tokyo (Japan)

    2010-04-15

    The hydrogen embrittlement property of a prototype 1700-MPa-class ultrahigh-strength steel (NIMS17) containing hydrogen traps was evaluated using a slow strain rate test (SSRT) after cathodic hydrogen precharging, cyclic corrosion test (CCT) and atmospheric exposure. The hydrogen content in a fractured specimen was measured after SSRT by thermal desorption spectroscopy (TDS). The relationship between fracture stress and hydrogen content for the hydrogen-precharged specimens showed that the fracture stress of NIMS17 steel was higher, at a given hydrogen content, than that of conventional AISI 4135 steels with tensile strengths of 1300 and 1500 MPa. This suggests better resistance of NIMS17 steel to hydrogen embrittlement. However, hydrogen uptake to NIMS17 steel under CCT and atmospheric exposure decreased the fracture stress. This is because of the stronger hydrogen uptake to the steel containing hydrogen traps than to the AISI 4135 steels. Although NIMS17 steel has a higher strength level than AISI 4135 steel with a tensile strength of 1500 MPa, the decrease in fracture stress is similar between these steels.

  13. Hydrogen embrittlement property of a 1700-MPa-class ultrahigh-strength tempered martensitic steel

    Directory of Open Access Journals (Sweden)

    Songjie Li, Eiji Akiyama, Kimura Yuuji, Kaneaki Tsuzaki, Nobuyoshi Uno and Boping Zhang

    2010-01-01

    Full Text Available The hydrogen embrittlement property of a prototype 1700-MPa-class ultrahigh-strength steel (NIMS17 containing hydrogen traps was evaluated using a slow strain rate test (SSRT after cathodic hydrogen precharging, cyclic corrosion test (CCT and atmospheric exposure. The hydrogen content in a fractured specimen was measured after SSRT by thermal desorption spectroscopy (TDS. The relationship between fracture stress and hydrogen content for the hydrogen-precharged specimens showed that the fracture stress of NIMS17 steel was higher, at a given hydrogen content, than that of conventional AISI 4135 steels with tensile strengths of 1300 and 1500 MPa. This suggests better resistance of NIMS17 steel to hydrogen embrittlement. However, hydrogen uptake to NIMS17 steel under CCT and atmospheric exposure decreased the fracture stress. This is because of the stronger hydrogen uptake to the steel containing hydrogen traps than to the AISI 4135 steels. Although NIMS17 steel has a higher strength level than AISI 4135 steel with a tensile strength of 1500 MPa, the decrease in fracture stress is similar between these steels.

  14. Hydrogen embrittlement property of a 1700-MPa-class ultrahigh-strength tempered martensitic steel

    International Nuclear Information System (INIS)

    Li Songjie; Zhang Boping; Akiyama, Eiji; Yuuji, Kimura; Tsuzaki, Kaneaki; Uno, Nobuyoshi

    2010-01-01

    The hydrogen embrittlement property of a prototype 1700-MPa-class ultrahigh-strength steel (NIMS17) containing hydrogen traps was evaluated using a slow strain rate test (SSRT) after cathodic hydrogen precharging, cyclic corrosion test (CCT) and atmospheric exposure. The hydrogen content in a fractured specimen was measured after SSRT by thermal desorption spectroscopy (TDS). The relationship between fracture stress and hydrogen content for the hydrogen-precharged specimens showed that the fracture stress of NIMS17 steel was higher, at a given hydrogen content, than that of conventional AISI 4135 steels with tensile strengths of 1300 and 1500 MPa. This suggests better resistance of NIMS17 steel to hydrogen embrittlement. However, hydrogen uptake to NIMS17 steel under CCT and atmospheric exposure decreased the fracture stress. This is because of the stronger hydrogen uptake to the steel containing hydrogen traps than to the AISI 4135 steels. Although NIMS17 steel has a higher strength level than AISI 4135 steel with a tensile strength of 1500 MPa, the decrease in fracture stress is similar between these steels.

  15. The Milieu of Damaged Alveolar Epithelial Type 2 Cells Stimulates Alveolar Wound Repair by Endogenous and Exogenous Progenitors

    Science.gov (United States)

    Buckley, Susan; Shi, Wei; Carraro, Gianni; Sedrakyan, Sargis; Da Sacco, Stefano; Driscoll, Barbara A.; Perin, Laura; De Filippo, Roger E.

    2011-01-01

    Alveolar epithelial integrity is dependent upon the alveolar milieu, yet the milieu of the damaged alveolar epithelial cell type 2 (AEC2) has been little studied. Characterization of its components may offer the potential for ex vivo manipulation of stem cells to optimize their therapeutic potential. We examined the cytokine profile of AEC2 damage milieu, hypothesizing that it would promote endogenous epithelial repair while recruiting cells from other locations and instructing their engraftment and differentiation. Bronchoalveolar lavage and lung extract from hyperoxic rats represented AEC2 in vivo damage milieu, and medium from a scratch-damaged AEC2 monolayer represented in vitro damage. CINC-2 and ICAM, the major cytokines detected by proteomic cytokine array in AEC2 damage milieu, were chemoattractive to normoxic AECs and expedited in vitro wound healing, which was blocked by their respective neutralizing antibodies. The AEC2 damage milieu was also chemotactic for exogenous uncommitted human amniotic fluid stem cells (hAFSCs), increasing migration greater than 20-fold. hAFSCs attached within an in vitro AEC2 wound and expedited wound repair by contributing cytokines migration inhibitory factor and plasminogen activator inhibitor 1 to the AEC2 damage milieu, which promoted wound healing. The AEC2 damage milieu also promoted differentiation of a subpopulation of hAFSCs to express SPC, TTF-1, and ABCA3, phenotypic markers of distal alveolar epithelium. Thus, the microenvironment created by AEC2 damage not only promotes autocrine repair but also can attract uncommitted stem cells, which further augment healing through cytokine secretion and differentiation. PMID:21700959

  16. Phytochemical screening and analgesic profile of the lyophilized aqueous extract obtained from Chrysobalanus icaco leaves in experimental protocols.

    Science.gov (United States)

    Araújo-Filho, Heitor G; Dias, Jessica Deise Santos; Quintans-Júnior, Lucindo J; Santos, Márcio R V; White, Pollyanna A S; Barreto, Rosana S S; Barreto, André S; Estevam, Charles S; Araujo, Silvan S; Almeida, Jackson R G S; Menezes, Irwin R A; Coutinho, Henrique D M; Quintans, Jullyana S S

    2016-12-01

    Chrysobalanus icaco L. (Chrysobalanaceae) has been used for the treatment of abdominal pain and cramps. Assess the chemical and pharmacological profile of the lyophilized aqueous extract from C. icaco leaves (AEC). Chromatographic methods were used to assess compounds from AEC. Mice were treated with vehicle (control group) or AEC (100, 200 or 400 mg/kg, p.o.) (group with 7-8 mice) and the analgesic profile was assessed employing the acetic acid-induced writhing, formalin, hot plate tests and hyperalgesia induced by carrageenan (CG) or tumour necrosis factor-alpha. The animal motor performance was assessed using rota-rod and grip strength tests. The chromatographic profile of AEC demonstrated the presence of terpenoid compounds. The acute pretreatment with AEC, at all doses, produced a significant (p acetic acid-induced writhing test. In the formalin test, AEC were effective in the second phase (p analgesic and anti-inflammatory properties. So, these results corroborate the experiments using the AEC in inflammatory pain protocols. Our results suggest that AEC act against inflammatory pain.

  17. Aktjorski duet dvuhh rezhissjorov / Ksenia Repson

    Index Scriptorium Estoniae

    Repson, Ksenia

    2006-01-01

    Raikini-nim. Vene Riiklik Teater "Satirikon" ja Pushkini-nim. teater toovad Tallinna ühisprojekti - Belgia näitekirjaniku A. Nothombi "Vaenlase kosmeetika", kus peaosa mängib Konstantin Raikin, lavastab Roman Kozak. Lisatud ka arvustusi vene ajakirjandusest

  18. 3D automatic exposure control for 64-detector row CT: Radiation dose reduction in chest phantom study

    Energy Technology Data Exchange (ETDEWEB)

    Matsumoto, Keiko, E-mail: palm_kei@yahoo.co.jp [Department of Radiology, Kobe University Graduate School of Medicine, Kobe, Hyogo (Japan); Department of Radiology, Yamanashi University, Shimokato, Yamanashi (Japan); Ohno, Yoshiharu; Koyama, Hisanobu; Kono, Atsushi [Department of Radiology, Kobe University Graduate School of Medicine, Kobe, Hyogo (Japan); Inokawa, Hiroyasu [Toshiba Medical Systems, Ohtawara, Tochigi (Japan); Onishi, Yumiko [Department of Radiology, Kobe University Graduate School of Medicine, Kobe, Hyogo (Japan); Nogami, Munenobu [Department of Radiology, Kobe University Graduate School of Medicine, Kobe, Hyogo (Japan); Division of Image-Based Medicine, Institute of Biomedical Research and Innovation, Kobe, Hyogo (Japan); Takenaka, Daisuke [Department of Radiology, Kobe University Graduate School of Medicine, Kobe, Hyogo (Japan); Araki, Tsutomu [Department of Radiology, Yamanashi University, Shimokato, Yamanashi (Japan); Sugimura, Kazuro [Department of Radiology, Kobe University Graduate School of Medicine, Kobe, Hyogo (Japan)

    2011-03-15

    Purpose: The purpose of this study was to determine the utility of three-dimensional (3D) automatic exposure control (AEC) for low-dose CT examination in a chest phantom study. Materials and methods: A chest CT phantom including simulated focal ground-glass opacities (GGOs) and nodules was scanned with a 64-detector row CT with and without AEC. Performance of 3D AEC included changing targeted standard deviations (SDs) of image noise from scout view. To determine the appropriate targeted SD number for identification, the capability of overall identification with the CT protocol adapted to each of the targeted SDs was compared with that obtained with CT without AEC by means of receiver operating characteristic analysis. Results: When targeted SD values equal to or higher than 250 were used, areas under the curve (Azs) of nodule identification with CT protocol using AEC were significantly smaller than that for CT protocol without AEC (p < 0.05). When targeted SD numbers at equal to or more than 180 were adapted, Azs of CT protocol with AEC had significantly smaller than that without AEC (p < 0.05). Conclusion: This phantom study shows 3D AEC is useful for low-dose lung CT examination, and can reduce the radiation dose while maintaining good identification capability and good image quality.

  19. Intermittent Intraoperative Neural Monitoring Technology in Minimally Invasive Video-Assisted Thyroidectomy: A Preliminary Study.

    Science.gov (United States)

    Hei, Hu; Zhai, Yifei; Qin, Jianwu; Song, Yongping

    2016-01-01

    Intraoperative neural monitoring (IONM) technology was applied in minimally invasive video-assisted thyroidectomy (MIVAT) to explore its safety and effectiveness. Data were collected retrospectively from October 2009 to August 2011. Inclusion criteria included the following: (1) benign thyroid nodule with maximum diameter less than 4.0 cm by preoperative ultrasound evaluation; (2) no previous thyroid surgeries; (3) no cervical radiation history; (4) normal function of recurrent laryngeal nerve (RLN) examined by preoperative laryngoscopy; (5) patients who did not accept to take a "wait and see" follow-up strategy. Enrolled patients were randomly allocated into NIM group and control group. 46 patients were enrolled in NIM group, and 51 patients were enrolled in control group. All surgeries in NIM group were performed successfully, and majority of tracheal intubations were placed with one attempt. 47 RLNs in NIM group and 60 RLNs in control group were exposed. The time of RLN locating was 6.06 ± 1.48 min in NIM group and 6.92 ± 1.34 min in control group (p = .02). The time of RLN tracing and exposing was 28.96 ± 4.75 min in NIM group and 32.17 ± 5.56 min in control group (p = .02). 1 case of temporary RLN paralysis was observed in both groups, and no permanent RLN paralysis was reported. The application of intermittent IONM in MIVAT is feasible. Intermittent IONM can help reduce the time of RLN locating and the time of RLN tracing and exposing.

  20. The synthesis and properties of nanoscale ionic materials

    KAUST Repository

    Rodriguez, Robert Salgado; Herrer, Rafael; Bourlinos, Athanasios B.; Li, Ruipeng; Amassian, Aram; Archer, Lynden A.; Giannelis, Emmanuel P.

    2010-01-01

    In this article we discuss the effect of constituents on structure, flow, and thermal properties of nanoscale ionic materials (NIMs). NIMs are a new class of nanohybrids consisting of a nanometer-sized core, a charged corona covalently attached

  1. Low dielectric and low surface free energy flexible linear aliphatic alkoxy core bridged bisphenol cyanate ester based POSS nanocomposites

    Directory of Open Access Journals (Sweden)

    Muthukaruppan eAlagar

    2013-10-01

    Full Text Available The aim of the present work is to develop a new type of flexible linear aliphatic alkoxy core bridged bisphenol cyanate ester (AECE based POSS nanocomposites for low k applications. The POSS-AECE nanocomposites were developed by incorporating varying weight percentages (0, 5 and 10 wt % of octakis (dimethylsiloxypropylglycidylether silsesquioxane (OG-POSS into cyanate esters. Data from thermal and dielectric studies imply that the POSS reinforced nanocomposite exhibits higher thermal stability and low dielectric value of k=2.4 (10 wt% POSS-AECE4 compared than those of neat AECE. From the contact angle measurement, it is inferred that, the increase in the percentage incorporation of POSS in to AECE, the values of water contact angle was enhanced. Further, the value of surface free energy was lower when compared to that of neat AECE. The molecular level dispersion of POSS into AECE was ascertained from SEM and TEM analyses.

  2. Establishment and evaluation of a stable cattle type II alveolar epithelial cell line.

    Directory of Open Access Journals (Sweden)

    Feng Su

    Full Text Available Macrophages and dendritic cells are recognized as key players in the defense against mycobacterial infection. Recent research has confirmed that alveolar epithelial cells (AECs also play important roles against mycobacterium infections. Thus, establishing a stable cattle AEC line for future endogenous immune research on bacterial invasion is necessary. In the present study, we first purified and immortalized type II AECs (AEC II cells by transfecting them with a plasmid containing the human telomerase reverse trancriptase gene. We then tested whether or not the immortalized cells retained the basic physiological properties of primary AECs by reverse-transcription polymerase chain reaction and Western blot. Finally, we tested the secretion capacity of immortalized AEC II cells upon stimulation by bacterial invasion. The cattle type II alveolar epithelial cell line (HTERT-AEC II that we established retained lung epithelial cell characteristics: the cells were positive for surfactants A and B, and they secreted tumor necrosis factor-α and interleukin-6 in response to bacterial invasion. Thus, the cell line we established is a potential tool for research on the relationship between AECs and Mycobacterium tuberculosis.

  3. [The toxic and hygienic characteristics of the new synthetic organic flocculants AES-5, AES-7 and AES-10].

    Science.gov (United States)

    Prokopov, V A; Nekrasova, L S; Mudryĭ, I V

    2000-03-01

    A toxicological and hygienic characterization is submitted of novel synthetic organic flocculant AEC-5, AEC-7, AEC-10 which are low-toxicity substances and are classified under the fourth class of hazards. They have no skin-resorptive, locally irritative action and are endowed with a weak cumulative activity of functional character. The AEC-5 flocculant exerts a moderately manifest sensitizing effect in the dermal route of entry.

  4. Direct contact between dendritic cells and bronchial epithelial cells inhibits T cell recall responses towards mite and pollen allergen extracts in vitro

    DEFF Research Database (Denmark)

    Papazian, Dick; Wagtmann, Valery R; Hansen, Soren

    2015-01-01

    (DCs), we have investigated recall T cell responses in allergic patients sensitized to house dust mite, grass, and birch pollen. Conclusions: Using allergen extract-loaded DCs to stimulate autologous allergen-specific T cell lines, we show that AEC-imprinted DCs inhibit T cell proliferation...... production of both Th1 and Th2 cytokines upon re-challenge. The inhibitory effects of AECs' contact with DCs were absent when allergen extract-loaded DCs had only been exposed to AECs supernatants, but present after direct contact with AECs. We conclude that direct contact between DCs and AECs inhibits T...

  5. The synthesis and properties of nanoscale ionic materials

    KAUST Repository

    Rodriguez, Robert Salgado

    2010-02-17

    In this article we discuss the effect of constituents on structure, flow, and thermal properties of nanoscale ionic materials (NIMs). NIMs are a new class of nanohybrids consisting of a nanometer-sized core, a charged corona covalently attached to the core, and an oppositely charged canopy. The hybrid nature of NIMs allows for their properties to be engineered by selectively varying their components. The unique properties associated with these systems can help overcome some of the issues facing the implementation of nanohybrids to various commercial applications, including carbon dioxide capture,water desalinization and as lubricants. Copyright © 2010 John Wiley & Sons, Ltd.

  6. Intra-connected three-dimensionally isotropic bulk negative index photonic metamaterial

    International Nuclear Information System (INIS)

    Guney, Durdu; Koschny, Thomas; Soukoulis, Costas

    2010-01-01

    Isotropic negative index metamaterials (NIMs) are highly desired, particularly for the realization of ultra-high resolution lenses. However, existing isotropic NIMs function only two-dimensionally and cannot be miniaturized beyond microwaves. Direct laser writing processes can be a paradigm shift toward the fabrication of three-dimensionally (3D) isotropic bulk optical metamaterials, but only at the expense of an additional design constraint, namely connectivity. Here, we demonstrate with a proof-of-principle design that the requirement connectivity does not preclude fully isotropic left-handed behavior. This is an important step towards the realization of bulk 3D isotropic NIMs at optical wavelengths.

  7. A Model for Translating Ethnography and Theory into Culturally Constructed Clinical Practices

    Science.gov (United States)

    Schensul, Jean J.; Schensul, Stephen L.; Mekki-Berrada, Abelwahed; Pelto, Pertti J.; Maitra, Shubhada; Verma, Ravi; Saggurti, Niranjan

    2015-01-01

    This article describes the development of a dynamic culturally constructed clinical practice model for HIV/STI prevention, the Narrative Intervention Model (NIM), and illustrates its application in practice, within the context of a 6-year transdisciplinary research program in Mumbai, India. Theory and research from anthropology, psychology, and public health, and mixed-method ethnographic research with practitioners, patients, and community members, contributed to the articulation of the NIM for HIV/STI risk reduction and prevention among married men living in low-income communities. The NIM involves a process of negotiation of patient narratives regarding their sexual health problems and related risk factors to facilitate risk reduction. The goal of the NIM is to facilitate cognitive-behavioral change through a three-stage process of co-construction (eliciting patient narrative), deconstruction (articulating discrepancies between current and desired narrative), and reconstruction (proposing alternative narratives that facilitate risk reduction). The NIM process extends the traditional clinical approach through the integration of biological, psychological, interpersonal, and cultural factors as depicted in the patient narrative. Our work demonstrates the use of a recursive integration of research and practice to address limitations of current evidence-based intervention approaches that fail to address the diversity of cultural constructions across populations and contexts. PMID:25292448

  8. A single-layer wide-angle negative-index metamaterial at visible frequencies.

    Science.gov (United States)

    Burgos, Stanley P; de Waele, Rene; Polman, Albert; Atwater, Harry A

    2010-05-01

    Metamaterials are materials with artificial electromagnetic properties defined by their sub-wavelength structure rather than their chemical composition. Negative-index materials (NIMs) are a special class of metamaterials characterized by an effective negative index that gives rise to such unusual wave behaviour as backwards phase propagation and negative refraction. These extraordinary properties lead to many interesting functions such as sub-diffraction imaging and invisibility cloaking. So far, NIMs have been realized through layering of resonant structures, such as split-ring resonators, and have been demonstrated at microwave to infrared frequencies over a narrow range of angles-of-incidence and polarization. However, resonant-element NIM designs suffer from the limitations of not being scalable to operate at visible frequencies because of intrinsic fabrication limitations, require multiple functional layers to achieve strong scattering and have refractive indices that are highly dependent on angle of incidence and polarization. Here we report a metamaterial composed of a single layer of coupled plasmonic coaxial waveguides that exhibits an effective refractive index of -2 in the blue spectral region with a figure-of-merit larger than 8. The resulting NIM refractive index is insensitive to both polarization and angle-of-incidence over a +/-50 degree angular range, yielding a wide-angle NIM at visible frequencies.

  9. A model for translating ethnography and theory into culturally constructed clinical practices.

    Science.gov (United States)

    Nastasi, Bonnie Kaul; Schensul, Jean J; Schensul, Stephen L; Mekki-Berrada, Abelwahed; Pelto, Pertti J; Maitra, Shubhada; Verma, Ravi; Saggurti, Niranjan

    2015-03-01

    This article describes the development of a dynamic culturally constructed clinical practice model for HIV/STI prevention, the Narrative Intervention Model (NIM), and illustrates its application in practice, within the context of a 6-year transdisciplinary research program in Mumbai, India. Theory and research from anthropology, psychology, and public health, and mixed-method ethnographic research with practitioners, patients, and community members, contributed to the articulation of the NIM for HIV/STI risk reduction and prevention among married men living in low-income communities. The NIM involves a process of negotiation of patient narratives regarding their sexual health problems and related risk factors to facilitate risk reduction. The goal of the NIM is to facilitate cognitive-behavioral change through a three-stage process of co-construction (eliciting patient narrative), deconstruction (articulating discrepancies between current and desired narrative), and reconstruction (proposing alternative narratives that facilitate risk reduction). The NIM process extends the traditional clinical approach through the integration of biological, psychological, interpersonal, and cultural factors as depicted in the patient narrative. Our work demonstrates the use of a recursive integration of research and practice to address limitations of current evidence-based intervention approaches that fail to address the diversity of cultural constructions across populations and contexts.

  10. Sexual dimorphism in an animal model of Sjögren's syndrome: a potential role for Th17 cells

    Directory of Open Access Journals (Sweden)

    Alexandria Voigt

    2015-11-01

    Full Text Available Sjögren's syndrome is a complex autoimmune disease with an array of diverse immunological, genetic and environmental etiologies, making identification of the precise autoimmune mechanism difficult to define. One of the most distinctive aspects of Sjögren's syndrome is the high sexual dimorphism with women affected 10-20 times more than men. It is nearly impossible to study the sexual dimorphic development of Sjögren's syndrome in human patients; therefore it is pertinent to develop an appropriate animal model which resembles human disease. The data indicated that female C57BL/6.NOD-Aec1Aec2 mice developed an earlier onset of sialadenitis with a higher composition of CD3+ T cells and a 10-fold increase in glandular infiltration of Th17 cells at the onset of clinical disease compared to male mice. Inflammatory Th17 cells of female mice exhibited a stronger proliferation in response to disease-specific antigen than their male counterpart. At the clinical disease stage, altered autoantibody patterns can be detected in females whereas they are seldom observed in male C57BL/6.NOD-Aec1Aec2 mice. Interestingly, male C57BL/6.NOD-Aec1Aec2 mice developed an earlier loss of secretory function, despite the fact that female C57BL/6.NOD-Aec1Aec2 mice exhibited a more rapid secretory loss. This data indicates the strong sexual dimorphism in the SjS-susceptible C57BL/6.NOD-Aec1Aec2 animal model, making it an appropriate animal model to examine human disease.

  11. Macroscopic barotrauma caused by stiff and soft-tipped airway exchange catheters: an in vitro case series.

    Science.gov (United States)

    Axe, Robert; Middleditch, Alex; Kelly, Fiona E; Batchelor, Tim J; Cook, Tim M

    2015-02-01

    Many airway management guidelines include the use of airway exchange catheters (AECs). There are reports, however, of harm from their use, from both malpositioning and in particular from the administration of oxygen via an AEC leading to barotrauma. We used an in vitro pig lung model to investigate the safety of administering oxygen at 4 different flow rates from a high-pressure source via 2 different AECs: a standard catheter and a soft-tipped catheter. Experiments were performed with the catheters positioned either above the carina or below it at the first point of resistance to advancement (hold-up). The experiments were then repeated to produce a series of 32 cases. With an AEC positioned above the carina, we did not observe macroscopic lung damage after the administration of oxygen. The administration of oxygen through an AEC positioned below the carina resulted in macroscopic barotrauma regardless of the rate of oxygen delivery. Increasing speed of oxygen flow led to faster and more extensive damage. Use of an "injector" at 2.5 or 4 bar led to instantaneous macroscopic lung damage and advancement of the AEC through the lung tissue. Our observations were the same when both types of AECs were used. Our results are consistent with reports of harm during the use of AECs and demonstrate the risk of administering oxygen through these devices when they are positioned below the carina. An indicator, ideally made on an AEC at the time of manufacture and designed to lie at the same level as the teeth, may be useful in preventing the insertion of that AEC beyond the level of the carina and improve the safety of using such devices.

  12. Enhanced rifampicin delivery to alveolar macrophages by solid lipid nanoparticles

    Energy Technology Data Exchange (ETDEWEB)

    Chuan Junlan [West China School of Pharmacy, Sichuan University, Key Laboratory of Drug Targeting and Drug Delivery System, Ministry of Education (China); Li Yanzhen [Tianjin Institute of Pharmaceutical Research, State Key Laboratory of Drug Delivery Technology and Pharmacokinetics (China); Yang Likai; Sun Xun [West China School of Pharmacy, Sichuan University, Key Laboratory of Drug Targeting and Drug Delivery System, Ministry of Education (China); Zhang Qiang [Peking University, State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences (China); Gong Tao, E-mail: gongtaoy@126.com; Zhang Zhirong, E-mail: zrzzl@vip.sina.com [West China School of Pharmacy, Sichuan University, Key Laboratory of Drug Targeting and Drug Delivery System, Ministry of Education (China)

    2013-05-15

    The present study aimed at developing a drug delivery system targeting the densest site of tuberculosis infection, the alveolar macrophages (AMs). Rifampicin (RFP)-loaded solid lipid nanoparticles (RFP-SLNs) with an average size of 829.6 {+-} 16.1 nm were prepared by a modified lipid film hydration method. The cytotoxicity of RFP-SLNs to AMs and alveolar epithelial type II cells (AECs) was examined using MTT assays. The viability of AMs and AECs was above 80 % after treatment with RFP-SLNs, which showed low toxicity to both AMs and AECs. Confocal Laser Scanning Microscopy was employed to observe the interaction between RFP-SLNs and both AMs and AECs. After incubating the cells with RFP-SLNs for 2 h, the fluorescent intensity in AMs was more and remained longer (from 0.5 to 12 h) when compared with that in AECs (from 0.5 to 8 h). In vitro uptake characteristics of RFP-SLNs in AMs and AECs were also investigated by detection of intracellular RFP by High performance liquid chromatography. Results showed that RFP-SLNs delivered markedly higher RFP into AMs (691.7 ng/mg in cultured AMs, 662.6 ng/mg in primary AMs) than that into AECs (319.2 ng/mg in cultured AECs, 287.2 ng/mg in primary AECs). Subsequently, in vivo delivery efficiency and the selectivity of RFP-SLNs were further verified in Sprague-Dawley rats. Under pulmonary administration of RFP-SLNs, the amount of RFP in AMs was significantly higher than that in AECs at each time point. Our results demonstrated that solid lipid nanoparticles are a promising strategy for the delivery of rifampicin to alveolar macrophages selectively.

  13. Eesti Teatriliidu aastapreemiad 1996

    Index Scriptorium Estoniae

    1997-01-01

    Aleksander Kurtna nim. preemia sai Anne Lange (T. S. Elioti, J. B. Priestley, W. Shakespeare'i, A. Milleri, E. J. Dunsany ja T. Kushneri näidendite tõlkimise eest); Priit Põldroosi nim. preemia sai Lilian Tamm (Vellerand) raamatu 'Linda Rummo. Elust ja lavaelust' koostamise eest

  14. Solution of Fractional Partial Differential Equations in Fluid Mechanics by Extension of Some Iterative Method

    Directory of Open Access Journals (Sweden)

    A. A. Hemeda

    2013-01-01

    Full Text Available An extension of the so-called new iterative method (NIM has been used to handle linear and nonlinear fractional partial differential equations. The main property of the method lies in its flexibility and ability to solve nonlinear equations accurately and conveniently. Therefore, a general framework of the NIM is presented for analytical treatment of fractional partial differential equations in fluid mechanics. The fractional derivatives are described in the Caputo sense. Numerical illustrations that include the fractional wave equation, fractional Burgers equation, fractional KdV equation, fractional Klein-Gordon equation, and fractional Boussinesq-like equation are investigated to show the pertinent features of the technique. Comparison of the results obtained by the NIM with those obtained by both Adomian decomposition method (ADM and the variational iteration method (VIM reveals that the NIM is very effective and convenient. The basic idea described in this paper is expected to be further employed to solve other similar linear and nonlinear problems in fractional calculus.

  15. Expression pattern of salt tolerance-related genes in Aegilops cylindrica.

    Science.gov (United States)

    Arabbeigi, Mahbube; Arzani, Ahmad; Majidi, Mohammad Mahdi; Sayed-Tabatabaei, Badraldin Ebrahim; Saha, Prasenjit

    2018-02-01

    Aegilops cylindrica , a salt-tolerant gene pool of wheat, is a useful plant model for understanding mechanism of salt tolerance. A salt-tolerant USL26 and a salt-sensitive K44 genotypes of A. cylindrica , originating from Uremia Salt Lake shores in Northwest Iran and a non-saline Kurdestan province in West Iran, respectively, were identified based on screening evaluation and used for this work. The objective of the current study was to investigate the expression patterns of four genes related to ion homeostasis in this species. Under treatment of 400 mM NaCl, USL26 showed significantly higher root and shoot dry matter levels and K + concentrations, together with lower Na + concentrations than K44 genotype. A. cylindrica HKT1;5 ( AecHKT1;5 ), SOS1 ( AecSOS1 ), NHX1 ( AecNHX1 ) and VP1 ( AecVP1 ) were partially sequenced to design each gene specific primer. Quantitative real-time PCR showed a differential expression pattern of these genes between the two genotypes and between the root and shoot tissues. Expressions of AecHKT1;5 and AecSOS1 was greater in the roots than in the shoots of USL26 while AecNHX1 and AecVP1 were equally expressed in both tissues of USL26 and K44. The higher transcripts of AecHKT1;5 in the roots versus the shoots could explain both the lower Na + in the shoots and the much lower Na + and higher K + concentrations in the roots/shoots of USL26 compared to K44. Therefore, the involvement of AecHKT1;5 in shoot-to-root handover of Na + in possible combination with the exclusion of excessive Na + from the root in the salt-tolerant genotype are suggested.

  16. Is Weight-Based Adjustment of Automatic Exposure Control Necessary for the Reduction of Chest CT Radiation Dose?

    Energy Technology Data Exchange (ETDEWEB)

    Prakash, Priyanka; Kalra, Mannudeep K.; Gilman, Matthew D.; Shepard, Jo Anne O.; Digumarthy, Subba R. [Massachusetts General Hospital and Harvard Medical School, Boston (United States)

    2010-02-15

    To assess the effects of radiation dose reduction in the chest CT using a weight-based adjustment of the automatic exposure control (AEC) technique. With Institutional Review Board Approval, 60 patients (mean age, 59.1 years; M:F = 35:25) and 57 weight-matched patients (mean age, 52.3 years, M:F = 25:32) were scanned using a weight-adjusted AEC and nonweight- adjusted AEC, respectively on a 64-slice multidetector CT with a 0.984:1 pitch, 0.5 second rotation time, 40 mm table feed/rotation, and 2.5 mm section thickness. Patients were categorized into 3 weight categories; < 60 kg (n = 17), 60-90 kg (n = 52), and > 90 kg (n = 48). Patient weights, scanning parameters, CT dose index volumes (CTDIvol) and dose length product (DLP) were recorded, while effective dose (ED) was estimated. Image noise was measured in the descending thoracic aorta. Data were analyzed using a standard statistical package (SAS/STAT) (Version 9.1, SAS institute Inc, Cary, NC). Compared to the non-weight-adjusted AEC, the weight-adjusted AEC technique resulted in an average decrease of 29% in CTDIvol and a 27% effective dose reduction (p < 0.0001). With weight-adjusted AEC, the CTDIvol decreased to 15.8, 15.9, and 27.3 mGy for the < 60, 60-90 and > 91 kg weight groups, respectively, compared to 20.3, 27.9 and 32.8 mGy, with non-weight adjusted AEC. No significant difference was observed for objective image noise between the chest CT acquired with the non-weight-adjusted (15.0 {+-} 3.1) and weight-adjusted (16.1 {+-} 5.6) AEC techniques (p > 0.05). The results of this study suggest that AEC should be tailored according to patient weight. Without weight-based adjustment of AEC, patients are exposed to a 17 - 43% higher radiation-dose from a chest CT.

  17. Factors Impacting Bank Net Interest Margin and the Role of Monetary Policy: Evidence from Turkey

    Directory of Open Access Journals (Sweden)

    Muhammed Hasan Yılmaz

    2017-10-01

    Full Text Available In this study, we investigate factors affecting net interest margin (NIM of commercial banks in Turkey. Especially, our results highlight the relation between unconventional monetary policy shocks and bank margins. To this end, first, we conduct an identification analysis about which parameters of asymmetric interest corridor framework are important in explaining variations in NIM. Using industry-level data, we show that there exists a pass through from BIST interbank overnight repo/reverse repo market rate and weighted average cost of funding (WACF to bank loan and deposit rates. As a result of reduced-form Vector Autoregression (VAR analysis we find the existence of a transmission mechanism from BIST rate and WACF to commercial loan rate, consumer loan rate and deposit rate. Same pass through to loan and deposit rates is also shown in individual bank level with the Panel Vector Autoregression (Panel VAR analysis in the case of 16 commercial banks in Turkey during the period 2011Q1-2016Q1. After the identification analysis, we examine the relationship between NIM and policy rates through System Generalized Method of Moments (GMM techniques by controlling bank specific, industry related and macroeconomic factors. We find that a change in the monetary policy rate has significant and positive impact on NIM. Among bank-specific factors, equity ratio and operating expenses are found to be significantly affecting NIM during the sample period. Our empirical findings also stress the significance of lag values of NIM. Estimations conducted with standardized variables indicate that economic significance of lag values and bank specific variables are larger than that of policy.

  18. Intermediate phases in the hydrogen disproportionated state of NdFeB-type powders

    International Nuclear Information System (INIS)

    Yi, G.; Chapman, J. N.; Brown, D. N.; Harris, I. R.

    2001-01-01

    Transmission electron microscopy studies have been carried out on partially disproportionated NdFeB-type alloys. A new intermediate magnetic (NIM) phase has been identified. Moreover, the lamella structure which subsequently develops from the tetragonal NIM phase comprises a tetragonal NdFe-containing (IL) phase and α-Fe. The experimental data show strong evidence of a well-defined crystallographic relation between both the NIM and lamella phases and between the IL phase and α-Fe. These observations give insight into how crystallographic texture, and hence anisotropy, can be developed in NdFeB-type powders processed by the hydrogenation, disproportionation, desorption, and recombination route. copyright 2001 American Institute of Physics

  19. EP&R Standards Project Report: Technical Review of National Incident Management Standards

    Energy Technology Data Exchange (ETDEWEB)

    Stenner, Robert D.

    2007-04-24

    The importance and necessity for a fully developed and implemented National Incident Management System (NIMS) has been demonstrated in recent years by the impact of national events such as Hurricane Katrina in 2005. Throughout the history of emergency response to major disasters, especially when multiple response organizations are involved, there have been systemic problems in the consistency and uniformity of response operations. Identifying national standards that support the development and implementation of NIMS is key to helping solve these systemic problems. The NIMS seeks to provide uniformity and consistency for incident management by using common terminology and protocols that will enable responders to coordinate their efforts to ensure an efficient response.

  20. Methods for implementing Building Information Modeling and Building Performance Simulation approaches

    DEFF Research Database (Denmark)

    Mondrup, Thomas Fænø

    methodologies. Thesis studies showed that BIM approaches have the potential to improve AEC/FM communication and collaboration. BIM is by its nature multidisciplinary, bringing AEC/FM project participants together and creating constant communication. However, BIM adoption can lead to technical challenges......, Engineering, Construction, and Facility Management (AEC/ FM) communication, and (b) BPS as a platform for early-stage building performance prediction. The second is to develop (a) relevant AEC/FM communication support instruments, and (b) standardized BIM and BPS execution guidelines and information exchange......, for example, getting BIM-compatible tools to communicate properly. Furthermore, BIM adoption requires organizational change, that is changes in AEC/FM work practices and interpersonal dynamics. Consequently, to ensure that the adoption of BIM is successful, it is recommended that common IT regulations...

  1. Reduced-dose chest CT with 3D automatic exposure control vs. standard chest CT: Quantitative assessment of emphysematous changes in smokers’ lung parenchyma

    International Nuclear Information System (INIS)

    Koyama, Hisanobu; Ohno, Yoshiharu; Yamazaki, Youichi; Matsumoto, Keiko; Onishi, Yumiko; Takenaka, Daisuke; Yoshikawa, Takeshi; Nishio, Mizuho; Matsumoto, Sumiaki; Murase, Kenya; Nishimura, Yoshihiro

    2012-01-01

    Objectives: To determine the capability of reduced-dose chest CT with three-dimensional (3D) automatic exposure control (AEC) on quantitative assessment of emphysematous change in smoker’ lung parenchyma, compared to standard chest CT. Methods: Twenty consecutive smoker patients (mean age 62.8 years) underwent CT examinations using a standard protocol (150 mAs) and a protocol with 3D-AEC. In this study, the targeted standard deviations number was set to 160. For quantitative assessment of emphysematous change in lung parenchyma in each subject using the standard protocol, a percentage of voxels less than −950 HU in the lung (%LAA −950 ) was calculated. The 3D-AEC protocol's %LAA was computed from of voxel percentages under selected threshold CT value. The differences of radiation doses between these two protocols were evaluated, and %LAAs −950 was compared with the 3D-AEC protocol %LAAs. Results: Mean dose length products were 780.2 ± 145.5 mGy cm (standard protocol), and 192.0 ± 95.9 (3D-AEC protocol). There was significant difference between them (paired Student's t test, p −950 and 3D-AEC protocol %LAAs. In adopting the feasible threshold CT values of the 3D-AEC protocol, the 3D-AEC protocol %LAAs were significantly correlated with %LAAs −950 (r = 0.98, p < 0.001) and limits of agreement from Bland–Altman analysis was 0.52 ± 4.3%. Conclusions: Changing threshold CT values demonstrated that reduced-dose chest CT with 3D-AEC can substitute for the standard protocol in assessments of emphysematous change in smoker’ lung parenchyma.

  2. Formerly utilized MED/AEC sites remedial action program. Radiological survey of the former Watertown arsenal property, Site 34 and Site 41, Watertown, Massachusetts

    International Nuclear Information System (INIS)

    Wynveen, R.A.; Smith, W.H.; Sholeen, C.M.; Justus, A.L.; Flynn, K.F.

    1983-10-01

    During the MED/AEC era, work involving radioactive materials was conducted at various sites within the arsenal complex. Building 34 housed a uranium machine shop, and a portion of Building 41 contained a foundry that was used for uranium work. Information provided by site personnel indicated that only depleted uranium was used in these buildings. Results of radiological analyses of contaminated material found at these sites indicated depleted uranium with uranium-236. Both buildings have been razed. The remnants still in place consist of the concrete floor slabs, access drives, and underground utility service trenches. This area is currently under the control of the Watertown Redevelopment Authority of Watertown, Massachusetts. During the period from June 25 through July 1, 1981, the Argonne National Laboratory (ANL), Occupational Health and Safety Division (OHS) Radiological Survey Group (RSG), conducted a radiological survey of Building Sites 34 and 41 at the direction of the US Department of Energy. Significant levels of contamination were found at 33 locations on the pad of Site 34 and in 5 out of 15 soild corings from the perimeter of the pad. No contamination was found on the pad of Site 41; however, two-thirds of this pad was covered with soil up to 4 ft thick. One of the 14 soil corings taken adjacent to the pad of Site 41 had elevated levels of uranium. Levels of contamination in excess of criteria, as identified in ANSI 13.12 and NRC Guidelines, were found at this site. The analyses of the samples from the sewer access points also revealed uranium and radium-226 anomalies. Therefore, according to NRC guidelines dated July 1982, it must be concluded that they are contaminated

  3. Should the automatic exposure control system of CT be disabled when scanning patients with endoaortic stents or mechanical heart valves? A phantom study.

    Science.gov (United States)

    Di Leo, Giovanni; Spadavecchia, Chiara; Zanardo, Moreno; Secchi, Francesco; Veronese, Ivan; Cantone, Marie Claire; Sardanelli, Francesco

    2017-07-01

    To estimate the impact of endoaortic stents/mechanical heart valves on the output of an automatic exposure control (AEC) system and CT radiation dose. In this phantom study, seven stents and two valves were scanned with varying tube voltage (80/100/120 kVp), AEC activation (enabled/disabled) and prosthesis (present/absent), for a total of 540 scans. For each prosthesis, the dose-length product (DLP) was compared between scans with the AEC enabled and disabled. Percentage confidence levels for differences due to the prosthesis were calculated. Differences between results with the AEC enabled and disabled were not statistically significant (p ≥ 0.059). In the comparison with and without the prosthesis, DLP was unchanged at 80 kVp and 100 kVp, while a slight increase was observed at 120 kVp. The radiation dose varied from 1.8 mGy to 2.4 mGy without the prosthesis and from 1.8 mGy to 2.5 mGy with the prosthesis (confidence level 37-100%). The effect of the prosthesis on the AEC system was negligible and not clinically relevant. Therefore, disabling the AEC system when scanning these patients is not likely to provide a benefit. • CT-AEC system is not impaired in patients with endoaortic prostheses/heart valves. • Negligible differences may be observed only at 120 kVp. • Disabling the AEC system in these patients is not recommended.

  4. Nuclear incident monitor criticality alarm instrument for the Savannah River Site: Technical manual

    International Nuclear Information System (INIS)

    Jenkins, J.B.

    1996-01-01

    The Savannah River Site is a Department of Energy facility. The facility stores, processes, and works with fissionable material at a number of locations. Technical standards and US Department of Energy orders, require these locations to be monitored by criticality alarm systems under certain circumstances. The Savannah River Site calls such instruments Nuclear Incident Monitors or NIMs. The Sole purpose of the Nuclear Incident Monitor is to provide an immediate evacuation signal in the case of an accidental criticality in order to minimize personnel exposure to radiation. The new unit is the third generation Nuclear Incident Monitor at the Savannah River Site. The second generation unit was developed in 1979. It was designed to eliminate vacuum-tube circuits, and was the first solid state NIM at SRS. The major design objectives of the second generation NIM were to improve reliability and reduce maintenance costs. Ten prototype units have been built and tested. This report describes the design of the new NIM and the testing that took place to verify its acceptability

  5. Intraoperative monitoring of marginal mandibular nerve during neck dissection.

    Science.gov (United States)

    Tirelli, Giancarlo; Bergamini, Pier Riccardo; Scardoni, Alessandro; Gatto, Annalisa; Boscolo Nata, Francesca; Marcuzzo, Alberto Vito

    2018-05-01

    The purpose of this study was to assess the efficacy of intraoperative nerve integrity monitoring (NIM) to prevent marginal mandibular nerve injuries during neck dissection. This prospective study compared 36 patients undergoing NIM-assisted neck dissection from July 2014 to March 2015 to a cohort of 35 patients subjected to neck dissection over an identical period of time before the technique was introduced. We also assessed possible correlations between marginal mandibular nerve injuries and other factors, such as anthropometric measurements, presence of clinical neck metastases, type of neck dissection, and site of primary tumor. The incidence of marginal mandibular nerve paralyses was significantly lower among the group of patients undergoing NIM-assisted neck dissection (P = .021). There was no significant difference in the duration of the procedure, and the technique resulted in a limited increase of cost. No other factor seemed to influence the onset of marginal mandibular nerve palsy. In our opinion, NIM is a valuable aid for preventing marginal mandibular nerve injuries during neck dissection. © 2018 Wiley Periodicals, Inc.

  6. Assessing the port to port risk of vessel movements vectoring non-indigenous marine species within and across domestic Australian borders.

    Science.gov (United States)

    Campbell, Marnie L; Hewitt, Chad L

    2011-07-01

    Biofouling of vessels is implicated as a high risk transfer mechanism of non-indigenous marine species (NIMS). Biofouling on international vessels is managed through stringent border control policies, however, domestic biofouling transfers are managed under different policies and legislative arrangements as they cross internal borders. As comprehensive guidelines are developed and increased compliance of international vessels with 'clean hull' expectations increase, vessel movements from port to port will become the focus of biosecurity management. A semi-quantitative port to port biofouling risk assessment is presented that evaluates the presence of known NIMS in the source port and determines the likelihood of transfer based on the NIMS association with biofouling and environmental match between source and receiving ports. This risk assessment method was used to assess the risk profile of a single dredge vessel during three anticipated voyages within Australia, resulting in negligible to low risk outcomes. This finding is contrasted with expectations in the literature, specifically those that suggest slow moving vessels pose a high to extreme risk of transferring NIMS species.

  7. A Knotworking Guideline for Building Projects

    DEFF Research Database (Denmark)

    Rasmussen, Mai; Gade, Anne Nørkjær; Jensen, Rasmus Lund

    2017-01-01

    to collaborate occurs. The Finnish method, Knotworking AEC, emphasizes both collaboration and structure of building projects, which accommodates the lack of collaboration in the practices of the AEC sector. However, the recent development of Knotworking AEC implies a lack of written articles on Knotworking AEC...... experiments were analysed by practice theoretical methods. The result of this research is a Knotworking Guideline for Building Projects indicating both the phases, the participants and the tasks of each phase. The contribution of the resultlies in the conduction of a Knotworking session from both a practical...

  8. Is Weight-Based Adjustment of Automatic Exposure Control Necessary for the Reduction of Chest CT Radiation Dose?

    Science.gov (United States)

    Prakash, Priyanka; Gilman, Matthew D.; Shepard, Jo-Anne O.; Digumarthy, Subba R.

    2010-01-01

    Objective To assess the effects of radiation dose reduction in the chest CT using a weight-based adjustment of the automatic exposure control (AEC) technique. Materials and Methods With Institutional Review Board Approval, 60 patients (mean age, 59.1 years; M:F = 35:25) and 57 weight-matched patients (mean age, 52.3 years, M:F = 25:32) were scanned using a weight-adjusted AEC and non-weight-adjusted AEC, respectively on a 64-slice multidetector CT with a 0.984:1 pitch, 0.5 second rotation time, 40 mm table feed/rotation, and 2.5 mm section thickness. Patients were categorized into 3 weight categories; 90 kg (n = 48). Patient weights, scanning parameters, CT dose index volumes (CTDIvol) and dose length product (DLP) were recorded, while effective dose (ED) was estimated. Image noise was measured in the descending thoracic aorta. Data were analyzed using a standard statistical package (SAS/STAT) (Version 9.1, SAS institute Inc, Cary, NC). Results Compared to the non-weight-adjusted AEC, the weight-adjusted AEC technique resulted in an average decrease of 29% in CTDIvol and a 27% effective dose reduction (p 91 kg weight groups, respectively, compared to 20.3, 27.9 and 32.8 mGy, with non-weight-adjusted AEC. No significant difference was observed for objective image noise between the chest CT acquired with the non-weight-adjusted (15.0 ± 3.1) and weight-adjusted (16.1 ± 5.6) AEC techniques (p > 0.05). Conclusion The results of this study suggest that AEC should be tailored according to patient weight. Without weight-based adjustment of AEC, patients are exposed to a 17 - 43% higher radiation-dose from a chest CT. PMID:20046494

  9. Eleventh annual report of radiation exposures for DOE and DOE contractor employees

    International Nuclear Information System (INIS)

    1978-01-01

    In 1968, the US Atomic Energy Commission (AEC) established a program for reporting certain occupationa radiation exposure information to a central radiation records repository maintained at the Union Carbide Computing Technology Center, Oak Ridge, Tennessee. Annual summaries (WASH-1350-R1 through WASH-1350-R6) were reported for the years 1968-1973 and included data on AEC contracter employees as well as employees of companies in the private sector licensed by the AEC. In January 1975, the operational functions of the AEC, including the maintenance of records on the occupational radiation exposure on contractor employees, were transferred to the Energy Research and Development Administration (ERDA) and the AEC's regulatory functions, including the reporting of information on the occupational radiation exposure of licenses, were transferred to the Nuclear Regulatory Commission (NRC). Previous AEC licenses then reported to NRC while the contractors reported to ERDA. On October 1, 1977, the Department of Energy (DOE) was formed and assumed the responsibilities of ERDA. This report contains the 1978 radiation exposure data for DOE and DOE contractors

  10. DISSEMINATION OF SALMONELLA ENTERICA SEQUENCE TYPES AMONG ASEAN ECONOMIC COMMUNITY COUNTRIES.

    Science.gov (United States)

    Patchanee, Prapas; Boonkhot, Phacharaporn; Kittiwan, Nattinee; Tadee, Pakpoom; Chotinun, Suwit

    2015-07-01

    Food-borne illness caused by Salmonella enterica remains a public health problem and results in economic loss worldwide. With the up-coming establish- ment of the ASEAN Economic Community (AEC) allowing unrestricted move- ment of labor and goods, there is a higher risk of pathogen transmission among the AEC countries. This study characterized and investigated the spatial and temporal associations of S. enterica strains isolated in AEC countries during 1940- 2012 compared with those isolated in northern-Thailand during 2011-2013. Of the 173 S. enterica strains examined, 68 sequence types (STs) and 32 clonal complexes (CCs) were identified by multi loci sequence typing. Twenty-one strains belonged to four sequence types new to AEC countries, and they constituted only two CCs. A number of strains originated from various countries with multiple hosts, were highlighted. There was evidence of strains circulating in the AEC region well over a decade. Such information will be important in formulating biosecurity measures, as well as in educating regarding the risk of disease transmission in AEC.

  11. Wnt-inducible protein (WISP-1 is a key regulator of alveolar epithelial cell hyperplasia in pulmonary fibrosis

    Directory of Open Access Journals (Sweden)

    Melanie Königshoff

    2006-12-01

    Full Text Available Fibrotic lung disease is characterized by distorted lung architecture and severe loss of respiratory function secondary to alveolar epithelial cell (AEC hyperplasia, enhanced extracellular matrix (ECM deposition and fibroblast proliferation. Repetitive epithelial injuries with impaired alveolar wound healing and altered AEC gene expression represent a trigger mechanism for development of fibrosis. To reveal gene regulatory networks in lung fibrosis, we compared gene expression profiles of freshly isolated AEC obtained from mice 14 days after saline or bleomycin (BM instillation using whole genome microarray analysis. Several genes of the Wnt signaling pathway, in particular WISP-1, a member of the CCN family, were highly regulated. WISP-1 protein expression was demonstrated in proliferating AEC in BM-treated lungs by immunofluorescence. When analyzing all six CCN family members, WISP-1 was upregulated the most 14 days after BM challenge, as analyzed by qRT-PCR. To elucidate WISP-1 function, cultured primary mouse AEC were stimulated with WISP-1 and demonstrated a 230% increase in proliferation, analyzed by 3H-thymidine incorporation. This was mediated through enhanced phosphorylation, but not expression of protein kinase B (PKB/Akt, as detected by immunoblot. Finally, increased expression of WISP-1 was detected in lung homogenates and isolated AEC from IPF patients, using qRT-PCR. Immunohistochemical analysis of WISP-1 and Ki67 verified the existence of hyperplastic and proliferative AEC expressing WISP-1 in vivo. Our study thus identifies WISP-1 as a novel regulator of AEC injury and repair, and suggests that WISP-1 is a key mediator in pulmonary fibrosis.

  12. The clinical course of asymptomatic esophageal candidiasis incidentally diagnosed in general health inspection.

    Science.gov (United States)

    Lee, Sang Pyo; Sung, In-Kyung; Kim, Jeong Hwan; Lee, Sun-Young; Park, Hyung Seok; Shim, Chan Sup

    2015-01-01

    Esophageal candidiasis mostly occurs in the immunocompromised host. However, it may also affect healthy people and is frequently asymptomatic. The clinical significance of asymptomatic esophageal candidiasis (AEC) is still unclear. The aims of the study were to investigate the prevalence of AEC during health inspection and to identify its predisposing factors and clinical significance. A total of 49,497 subjects who underwent a health inspection that included upper endoscopy were enrolled. We retrospectively reviewed the subject's self-reporting questionnaires, medical records and endoscopic findings. We considered "long-term" follow-up to be >6 months with at least one more follow-up endoscopy. One hundred and seventy (0.4%) subjects were endoscopically diagnosed as esophageal candidiasis and 141 subjects were AEC. Multivariate analysis revealed that old age (≥60 years) was an independent risk factor for AEC (OR, 1.862, p = 0.005). The number of subjects with long-term follow-up was 79 (195.3 person-years). Among these, AEC of 64 subjects (81.0%) had disappeared on the follow-up endoscopy and was not recurrent. The other 15 subjects had AEC diagnosed more than once on the follow-up endoscopy, and 5 of them were spontaneously healed during the follow-up period. The remaining 10 subjects whose candidiasis was sustained up to the last endoscopy did not complain of symptoms during the follow-up period, and their endoscopic findings did not worsen. AEC is rare and old age is the only risk factor. AEC does not require medical care because it is a self-limited disease.

  13. The adenylate energy charge as a new and useful indicator of capture stress in chondrichthyans.

    Science.gov (United States)

    Guida, Leonardo; Walker, Terence I; Reina, Richard D

    2016-02-01

    Quantifying the physiological stress response of chondrichthyans to capture has assisted the development of fishing practices conducive to their survival. However, currently used indicators of stress show significant interspecific and intraspecific variation in species' physiological responses and tolerances to capture. To improve our understanding of chondrichthyan stress physiology and potentially reduce variation when quantifying the stress response, we investigated the use of the adenylate energy charge (AEC); a measure of available metabolic energy. To determine tissues sensitive to metabolic stress, we extracted samples of the brain, heart, liver, white muscle and blood from gummy sharks (Mustelus antarcticus) immediately following gillnet capture and after 3 h recovery under laboratory conditions. Capture caused significant declines in liver, white muscle and blood AEC, whereas no decline was detected in the heart and brain AEC. Following 3 h of recovery from capture, the AEC of the liver and blood returned to "unstressed" levels (control values) whereas white muscle AEC was not significantly different to that immediately after capture. Our results show that the liver is most sensitive to metabolic stress and white muscle offers a practical method to sample animals non-lethally for determination of the AEC. The AEC is a highly informative indicator of stress and unlike current indicators, it can directly measure the change in available energy and thus the metabolic stress experienced by a given tissue. Cellular metabolism is highly conserved across organisms and, therefore, we think the AEC can also provide a standardised form of measuring capture stress in many chondrichthyan species.

  14. CT dose modulation using automatic exposure control in whole-body PET/CT: effects of scout imaging direction and arm positioning.

    Science.gov (United States)

    Inoue, Yusuke; Nagahara, Kazunori; Kudo, Hiroko; Itoh, Hiroyasu

    2018-01-01

    Automatic exposure control (AEC) modulates tube current and consequently X-ray exposure in CT. We investigated the behavior of AEC systems in whole-body PET/CT. CT images of a whole-body phantom were acquired using AEC on two scanners from different manufactures. The effects of scout imaging direction and arm positioning on dose modulation were evaluated. Image noise was assessed in the chest and upper abdomen. On one scanner, AEC using two scout images in the posteroanterior (PA) and lateral (Lat) directions provided relatively constant image noise along the z-axis with the arms at the sides. Raising the arms increased tube current in the head and neck and decreased it in the body trunk. Image noise increased in the upper abdomen, suggesting excessive reduction in radiation exposure. AEC using the PA scout alone strikingly increased tube current and reduced image noise in the shoulder. Raising the arms did not substantially influence dose modulation and decreased noise in the abdomen. On the other scanner, AEC using the PA scout alone or Lat scout alone resulted in similar dose modulation. Raising the arms increased tube current in the head and neck and decreased it in the trunk. Image noise was higher in the upper abdomen than in the middle and lower chest, and was not influenced by arm positioning. CT dose modulation using AEC may vary greatly depending on scout direction. Raising the arms tended to decrease radiation exposure; however, the effect depends on scout direction and the AEC system.

  15. Editorial to NIM-B

    Science.gov (United States)

    McDaniel, Floyd Del; Doyle, Barney L.; Glass, Gary; Wang, Yongqiang; Antolak, Arlyn

    2018-01-01

    This special issue of Nuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms contains 7 selected papers that were presented at the 24th International Conference on the Application of Accelerators in Research and Industry (CAARI 2016). This conference was held in Fort Worth, Texas, USA, October 30 - November 4, 2016 and the Worthington Renaissance Hotel. CAARI 2016 had 5 plenary sessions, 79 oral sessions, 2 poster sessions, 401 presentations (10 plenary talks, 165 invited talks, 154 contributed talks, and 72 poster presentations), and 434 attendees (76 of which were students and 14 were accompanying persons) from 32 countries.

  16. The in vitro protection of human decay accelerating factor and hDAF/heme oxygenase-1 transgenes in porcine aortic endothelial cells against sera of Formosan macaques.

    Science.gov (United States)

    Tu, C-F; Tai, H-C; Wu, C-P; Ho, L-L; Lin, Y-J; Hwang, C-S; Yang, T-S; Lee, J-M; Tseng, Y-L; Huang, C-C; Weng, C-N; Lee, P-H

    2010-01-01

    To mitigate hyperacute rejection, pigs have been generated with alpha-Gal transferase gene knockout and transgenic expression of human decay accelerating factor (hDAF), MCP, and CD59. Additionally, heme-oxygenase-1 (HO-1) has been suggested to defend endothelial cells. Sera (MS) (0%, 1%, 5%, 10%, and 15%) from Formosan macaques (Macaca cyclopis, MC), an Old World monkey wildly populated in Taiwan, was used to test the protective in vitro, effects of hDAF or hDAF/hHO-1 on porcine aortic endothelial cells (pAEC) derived from hDAF(+), hDAF(+)/hHO-1(+), and hDAF(+)/hHO-1(-) and 1 nontransgenic pAEC. Ten percent human serum (HS) served as a positive control. When MS addition increased to 10% or 15%, all transgenic pAEC exhibited a greater survival than nontransgenic pAEC. Noticeably, 15% MS reduced survived to 40% in nontransgenic and transgenic pAEC, respectively. These results revealed that hDAF exerted protective effects against MC complement activation. However, comparing with 10% MS and HS in pAEC of nontransgenic pigs, the survivability was higher in HS, suggesting that complement activation by MS was more toxic than that by HS. Furthermore, hDAF(+)/hHO-1(+) showed no further protection against effects of MS on transgenic pAEC. Copyright 2010 Elsevier Inc. All rights reserved.

  17. Automatic exposure control in pediatric and adult multidetector CT examinations: A phantom study on dose reduction and image quality

    Energy Technology Data Exchange (ETDEWEB)

    Papadakis, Antonios E.; Perisinakis, Kostas; Damilakis, John [Department of Medical Physics, Faculty of Medicine, University of Crete, P.O. Box 1352, Iraklion 71110, Crete (Greece)

    2008-10-15

    The aim of this study was to assess the potential of a modern x,y,z modulation-based automatic exposure control system (AEC) for dose reduction in pediatric and adult multidetector CT (MDCT) imaging and evaluate the quality of the images obtained. Five physical anthropomorphic phantoms that simulate the average individual as neonate, 1-, 5-, 10-year old child, and adult were scanned with a MDCT scanner, equipped with a modern AEC system. Dose reduction (%DR) was calculated as the percentage difference of the mean modulated and the preset tube current-time product that is prescribed for standard head and body scan protocols. The effect of the tube potential and the orientation of the topogram acquisition on dose reduction were assessed. Image quality was evaluated on the basis of image noise and signal to noise ratio (SNR). The dose reduction values achieved in pediatric phantoms were remarkably lower than those achieved for the adult. The efficiency of the AEC is decreased at 80 kVp compared to higher tube potentials and for helical scans following an anterior posterior (AP-AEC) compared to a lateral (LAT-AEC) topogram acquisition. In AP-AEC scans, the dose reduction ranged between 4.7 and 34.7% for neonate, 15.4 and 30.9% for 1 year old, 3.1 and 26.7% for 5 years old, 1.2 and 58.7% for 10 years old, and 15.5 and 57.4% for adult. In LAT-AEC scans, the corresponding dose reduction ranged between 11.0 and 36.5%, 27.2 and 35.7%, 11.3 and 35.6%, 0.3 and 67.0%, and 15.0 and 61.7%, respectively. AP-AEC scans resulted in a 17.1% and 19.7% dose increase in the thorax of neonate and the pelvis of the 10-year old phantom, respectively. The variation in the measured noise among images obtained along the scanning z axis was lower in AEC activated compared to fixed milliamperes scans. However, image noise was significantly increased (P<.001) and SNR significantly decreased (P<.001) in most AEC activated compared to fixed milliamperes scans. In conclusion, AEC resulted in a (i

  18. Fifty per cent reduction in solution gas flaring : a report to the Saddle Hills Awareness Committee

    International Nuclear Information System (INIS)

    1999-01-01

    Information by the Alberta Energy Company to the Saddle Hills Awareness Committee (SHAC) regarding company operations in the West Peace River Arch of the western Canadian Sedimentary Basin in northwest Alberta is presented, the purpose being to bring the Committee up-to-date, and respond to concerns about the health effects of sour gas emissions. The SHAC represents citizens who are concerned about issues relating to sour gas emissions. AEC West, a business unit of Alberta Energy Company, operates two sour gas processing plants, one sweet gas plant and three sour oil batteries in the Grande Prairie area. AEC's gas plants are connected by pipelines and process petroleum and natural gas products from approximately 200 oil and gas wells. The H 2 S content of the natural gas being processed by AEC's various plants ranges from trace amounts to 11 per cent. Activities at AEC's Hythe plant and at the Sexsmith plant, and the company's gas storage project are briefly reviewed. An analysis is included of the role that flaring plays in the petroleum and natural gas industry, emphasizing AEC West's efforts during 1997 to reduce solution gas flaring volumes from single well oil batteries by 50 per cent. Other AEC West environmental protection initiatives include the preliminary regional airshed study sponsored by the company which resulted in part from SHAC feedback and in part from the innovative approach of AEC employees. AEC West established the industry's first Ombudsman to provide a problem resolution focus on landowner complaints and introduced a policy of making available solution gas that would eventually be flared to industrial colleagues, free of charge

  19. Eficiência e efeitos subletais de nim sobre Bonagota salubricola (Meyrick (Lepidoptera: Tortricidae Efficiency and sublethal effects of neem on Bonagota salubricola (Meyrick (Lepidoptera: Tortricidae

    Directory of Open Access Journals (Sweden)

    Daniel Bernardi

    2011-06-01

    Full Text Available O objetivo deste trabalho foi avaliar a eficiência e os efeitos subletais de um inseticida à base de nim (10 g.L-1 de azadiractina A sobre a lagarta-enroladeira Bonagota salubricola em laboratório. Nos bioensaios, foi utilizado o produto à base de azadiractina NeemAzal-T/S® nas concentrações de 0,06%; 0,09%; 0,12%; 0,16%; 0,18% e 0,20% do produto comercial (p.c e uma testemunha (água destilada. A dieta artificial foi cortada em cubos e imersa nas caldas das respectivas concentrações do produto, e, em seguida, lagartas recém-eclodidas foram transferidas para tubos de vidro, contendo os cubos de dieta tratados. Quando a dieta artificial foi tratada com concentração de 0,20% do produto comercial, houve 100% da mortalidade aos 6 dias após a inoculação. Por outro lado, as concentrações de 0,16 e 0,18% prolongaram a fase larval, reduziram a viabilidade de pupas e afetaram negativamente a fecundidade do inseto.The objective of this study was to evaluate the efficiency of control and sublethal effects of neem insecticide (10 g.L-1 of azadirachtin A to the leafroller Bonagota salubricola at laboratory condition. In the bioassays, it was used an azadirachtin based product (NeemAzal-T/S® at concentrations of 0.06%, 0.09%, 0.12%, 0.16%, 0.18% and 0.20% of the commercial product (c.p. and a control (distilled water. The artificial diet was cut in cubes and immersed in the syrups of the respective product concentrations, soon afterwards recently-emerged caterpillars were transferred to glass tubes, containing the diet cubes treated. When the artificial diet was treated with a concentration of 0.20% of the commercial product, the mortality was 100% at the 6th day after inoculation. Additionally, concentrations of 0.16% and 0.18% extended the larval stages, reduced pupae viability and negatively affected the fecundity of the insect.

  20. Markers of Pluripotency in Human Amniotic Epithelial Cells and Their Differentiation to Progenitor of Cortical Neurons

    Science.gov (United States)

    García-Castro, Irma Lydia; García-López, Guadalupe; Ávila-González, Daniela; Flores-Herrera, Héctor; Molina-Hernández, Anayansi; Portillo, Wendy; Ramón-Gallegos, Eva; Díaz, Néstor Fabián

    2015-01-01

    Human pluripotent stem cells (hPSC) have promise for regenerative medicine due to their auto-renovation and differentiation capacities. Nevertheless, there are several ethical and methodological issues about these cells that have not been resolved. Human amniotic epithelial cells (hAEC) have been proposed as source of pluripotent stem cells. Several groups have studied hAEC but have reported inconsistencies about their pluripotency properties. The aim of the present study was the in vitro characterization of hAEC collected from a Mexican population in order to identify transcription factors involved in the pluripotency circuitry and to determine their epigenetic state. Finally, we evaluated if these cells differentiate to cortical progenitors. We analyzed qualitatively and quantitatively the expression of the transcription factors of pluripotency (OCT4, SOX2, NANOG, KLF4 and REX1) by RT-PCR and RT-qPCR in hAEC. Also, we determined the presence of OCT4, SOX2, NANOG, SSEA3, SSEA4, TRA-1-60, E-cadherin, KLF4, TFE3 as well as the proliferation and epigenetic state by immunocytochemistry of the cells. Finally, hAEC were differentiated towards cortical progenitors using a protocol of two stages. Here we show that hAEC, obtained from a Mexican population and cultured in vitro (P0-P3), maintained the expression of several markers strongly involved in pluripotency maintenance (OCT4, SOX2, NANOG, TFE3, KLF4, SSEA3, SSEA4, TRA-1-60 and E-cadherin). Finally, when hAEC were treated with growth factors and small molecules, they expressed markers characteristic of cortical progenitors (TBR2, OTX2, NeuN and β-III-tubulin). Our results demonstrated that hAEC express naïve pluripotent markers (KLF4, REX1 and TFE3) as well as the cortical neuron phenotype after differentiation. This highlights the need for further investigation of hAEC as a possible source of hPSC. PMID:26720151

  1. Mobile Networked Sensors for Environmental Observatories

    Science.gov (United States)

    Kaiser, W. J.

    2005-12-01

    The development of the first embedded networked sensing (ENS) systems has been rapidly followed by their successful deployment for investigations in environments ranging from forest ecosystems, to rivers and lakes, and to subsurface soil observations. As ENS systems have been deployed, many technology challenges have been successfully addressed. For example, the requirements for local and remote data access and long operating life have been encountered and solved with a novel hierarchical network architecture and unique, low power platforms. This presentation will describe this progress and also the development and applications of a new ENS system addressing the most current challenges: A robotic ENS platform providing precise, reliable, and sustained observation capability with diverse sensing capabilities that may adapt to environmental dynamics. In the development of methods for autonomous observation by networked sensors, many applications have emerged requiring spatially and temporally intensive data sampling. Examples include the mapping of forest understory solar radiation, autonomous acquisition of imaging for plant phenology, and mapping of contaminant concentration in aquatic systems. Common to these applications is the need to actively and continuously configure the location and orientation of sensors for high fidelity mapping of the spatial distribution of phenomena. To address this primary environmental observation need, a new sensing platform, Networked Infomechanical Systems (NIMS) has been developed. NIMS relies on deployed aerial infrastructure (for example, cable suspension systems) in the natural environment to permit robotic devices to precisely and reliably move or remain stationary as required at elevations that may lie directly in or above the forest canopy or within a river or stream. NIMS systems are suspended to allow devices to translate a sensor node horizontally, and also to raise and lower devices. Examples of sensors that are now

  2. Human amniotic epithelial cell feeder layers maintain mouse embryonic stem cell pluripotency via epigenetic regulation of the c-Myc promoter.

    Science.gov (United States)

    Liu, Te; Cheng, Weiwei; Liu, Tianjin; Guo, Lihe; Huang, Qin; Jiang, Lizhen; Du, Xiling; Xu, Fuhui; Liu, Zhixue; Lai, Dongmei

    2010-02-01

    Mouse embryonic stem cells (ESCs) are typically cultured on a feeder layer of mouse embryonic fibroblasts (MEFs), with leukemia inhibitory factor (LIF) added to maintain them in an undifferentiated state. We have previously shown that human amniotic epithelial cells (hAECs) can be used as feeder cells to maintain mouse ESC pluripotency, but the mechanism for this is unknown. In the present study, we found that CpG islands 5' of the c-Myc gene remain hypomethylated in mouse ESCs cultured on hAECs. In addition, levels of acetylation of histone H3 and trimethylation of histone H3K4 in the c-Myc gene promoter were higher in ES cells cultured on hAECs than those in ES cells cultured on MEFs. These data suggested that hAECs can alter mouse ESC gene expression via epigenetic modification of c-Myc, providing a possible mechanism for the hAEC-induced maintenance of ESCs in an undifferentiated state.

  3. OPPORTUNITIES AND CHALLENGES FOR MICRO-SMALL AND MEDIUM BUSINESS IN INDONESIA FACING ASEAN ECONOMIC COMMUNITY

    Directory of Open Access Journals (Sweden)

    Raden Aswin Rahadi

    2016-03-01

    Full Text Available This research is a part of a continuous study to analyze the opportunities and challenges for micro-small and medium business in Indonesia when facing ASEAN Economic Community (AEC in 2016. It has its own uniqueness, as it will combine the point of view between current business owners and current literature study synthesis on business perception towards AEC. Ten business owners have been interviewed. The results suggested AEC provides challenges for the business owners, particularly in terms of capital; competitiveness; sales system; innovation; finance, bureaucracy; and government preparedness. AEC also provides opportunities, in terms of market potential; creativity; export opportunities; business owners’ resistances and sustainability; and knowledge of local market. From all of the keywords mentioned by the respondents, there are four main attributes considered as important: human resources; creativities; market share; and capital. Finally, most of the respondents suggested that AEC will bring more positive influences for the development of micro-small and medium business in Indonesia.

  4. Evaluation of the anterior and posterior ethmoidal canal by computed tomography

    International Nuclear Information System (INIS)

    Cankal, F.; Apaydin, N.; Acar, H.I.; Elhan, A.; Tekdemir, I.; Yurdakul, M.; Kaya, M.; Esmer, A.F.

    2004-01-01

    AIM: To examine the anatomy, length and angulation of the anterior and posterior ethmoidal canals (AECs and PECs) using computed tomography (CT), and to determine the anatomical landmarks in which the canals are expected to be seen in transverse and coronal planes. MATERIALS AND METHODS: CT images of 150 patients were analysed. One, 2, and 3 mm thick sections were obtained separately in axial and coronal images. The frequency of visualization of the AECs and PECs, and if present, a third canal, was noted. The course and the angulation of the AEC and the PEC in transverse and coronal planes were recorded. On axial sections the distance between the AEC and PEC and the previously defined landmarks were measured. On coronal images, the distances were calculated from the thickness of the cross-section and the number of sections between the various structures. RESULTS: The AEC was identified as a separate canal in 84% of patients, and was embedded in the ethmoid roof in 16%. The PEC was seen as a separate canal in 8% and was present in the ethmoid roof in 92%. On the 1 mm thick coronal and transverse sections, a third canal was identified at the junction of the middle and posterior third of the AEC-PEC distance in both of the images. The average lengths of these canals were 4-12 mm (mean 8.2 mm) for the AEC, and 2-13 mm (mean 7.6 mm) for the PEC. CONCLUSIONS: To avoid the complications that can develop during endoscopic sinus surgery; the course, length and the angulations of the anterior and posterior ethmoidal arteries and their canals can be identified by CT in standard positions if a sufficiently thin section thickness is used. The present study has shown the exact CT localization of the AECs and PECS, which are frequently overlooked when evaluating para-nasal sinuses

  5. Automatic exposure control in computed tomography - an evaluation of systems from different manufacturers

    Energy Technology Data Exchange (ETDEWEB)

    Soederberg, Marcus; Gunnarsson, Mikael (Dept. of Medical Radiation Physics, Skaane Univ. Hospital, Malmoe (Sweden)), e-mail: marcus.soderberg@med.lu.se

    2010-07-15

    Background: Today, practically all computed tomography (CT) systems are delivered with automatic exposure control (AEC) systems operating with tube current modulation in three dimensions. Each of these systems has different specifications and operates somewhat differently. Purpose: To evaluate AEC systems from four different CT scanner manufacturers: General Electric (GE), Philips, Siemens, and Toshiba, considering their potential for reducing radiation exposure to the patient while maintaining adequate image quality. Material and Methods: The dynamics (adaptation along the longitudinal axis) of tube current modulation of each AEC system were investigated by scanning an anthropomorphic chest phantom using both 16- and 64-slice CT scanners from each manufacturer with the AEC systems activated and inactivated. The radiation dose was estimated using the parameters in the DICOM image information and image quality was evaluated based on image noise (standard deviation of CT numbers) calculated in 0.5 cm2 circular regions of interest situated throughout the spine region of the chest phantom. Results: We found that tube current modulation dynamics were similar among the different AEC systems, especially between GE and Toshiba systems and between Philips and Siemens systems. Furthermore, the magnitude of the reduction in the exposure dose was considerable, in the range of 35-60%. However, in general the image noise increased when the AEC systems were used, especially in regions where the tube current was greatly decreased, such as the lung region. However, the variation in image noise among images obtained along the scanning direction was lower when using the AEC systems compared with fixed mAs. Conclusion: The AEC systems available in modern CT scanners can contribute to a significant reduction in radiation exposure to the patient and the image noise becomes more uniform within any given scan.

  6. Retorika, javno razpravljanje in spor o racionalnosti

    OpenAIRE

    Škerlep, Andrej

    2015-01-01

    V članku obravnavamo razmerje med retoriko in javnim razpravljanjem prek prikaza Habermasove nesposobnosti, da bi integriral retoriko v svojo teorijo racionalne argumentacije. V sporu med filozofijo in retoriko najprej izpostavljamo polemiko med modernisitčnim racionalizmom in postmodernističnim antiracionalizmom, nato pa v drugem delu članka ta spor obravnavamo še v okviru Platonovega in Aristotelovega pojmovanja retorike. Zastopamo tezo, da je Habermasova nesposobnost integracije retorike š...

  7. Should the automatic exposure control system of CT be disabled when scanning patients with endoaortic stents or mechanical heart valves? A phantom study

    Energy Technology Data Exchange (ETDEWEB)

    Di Leo, Giovanni; Zanardo, Moreno; Secchi, Francesco [IRCCS Policlinico San Donato, Radiology Unit, San Donato Milanese (Italy); Spadavecchia, Chiara [Universita degli Studi di Milano, Dipartimento di Fisica, Milano (Italy); Veronese, Ivan [Universita degli Studi di Milano, Dipartimento di Fisica, Milano (Italy); Istituto Nazionale di Fisica Nucleare, Sezione di Milano (Italy); Cantone, Marie Claire [Istituto Nazionale di Fisica Nucleare, Sezione di Milano (Italy); Universita degli Studi di Milano, Dipartimento di Scienze Biomediche, Chirurgiche ed Odontoiatriche, Milano (Italy); Sardanelli, Francesco [IRCCS Policlinico San Donato, Radiology Unit, San Donato Milanese (Italy); Universita degli Studi di Milano, Department of Biomedical Science for Health, San Donato Milanese (Italy)

    2017-07-15

    To estimate the impact of endoaortic stents/mechanical heart valves on the output of an automatic exposure control (AEC) system and CT radiation dose. In this phantom study, seven stents and two valves were scanned with varying tube voltage (80/100/120 kVp), AEC activation (enabled/disabled) and prosthesis (present/absent), for a total of 540 scans. For each prosthesis, the dose-length product (DLP) was compared between scans with the AEC enabled and disabled. Percentage confidence levels for differences due to the prosthesis were calculated. Differences between results with the AEC enabled and disabled were not statistically significant (p ≥ 0.059). In the comparison with and without the prosthesis, DLP was unchanged at 80 kVp and 100 kVp, while a slight increase was observed at 120 kVp. The radiation dose varied from 1.8 mGy to 2.4 mGy without the prosthesis and from 1.8 mGy to 2.5 mGy with the prosthesis (confidence level 37-100%). The effect of the prosthesis on the AEC system was negligible and not clinically relevant. Therefore, disabling the AEC system when scanning these patients is not likely to provide a benefit. (orig.)

  8. Should the automatic exposure control system of CT be disabled when scanning patients with endoaortic stents or mechanical heart valves? A phantom study

    International Nuclear Information System (INIS)

    Di Leo, Giovanni; Zanardo, Moreno; Secchi, Francesco; Spadavecchia, Chiara; Veronese, Ivan; Cantone, Marie Claire; Sardanelli, Francesco

    2017-01-01

    To estimate the impact of endoaortic stents/mechanical heart valves on the output of an automatic exposure control (AEC) system and CT radiation dose. In this phantom study, seven stents and two valves were scanned with varying tube voltage (80/100/120 kVp), AEC activation (enabled/disabled) and prosthesis (present/absent), for a total of 540 scans. For each prosthesis, the dose-length product (DLP) was compared between scans with the AEC enabled and disabled. Percentage confidence levels for differences due to the prosthesis were calculated. Differences between results with the AEC enabled and disabled were not statistically significant (p ≥ 0.059). In the comparison with and without the prosthesis, DLP was unchanged at 80 kVp and 100 kVp, while a slight increase was observed at 120 kVp. The radiation dose varied from 1.8 mGy to 2.4 mGy without the prosthesis and from 1.8 mGy to 2.5 mGy with the prosthesis (confidence level 37-100%). The effect of the prosthesis on the AEC system was negligible and not clinically relevant. Therefore, disabling the AEC system when scanning these patients is not likely to provide a benefit. (orig.)

  9. The Effects of the ASEAN Economic Community 2015 on Industries in Kitakyushu and Shimonoseki

    OpenAIRE

    エリック D., ラムステッター; Archanun, Kohpaiboon; Eric D., Ramstetter; Kohpaiboon, Archanun

    2015-01-01

    This paper asks how the formation of the Association of Southeast Asian Nations'(ASEAN's) Economic Community (AEC) in 2015 (AEC2015) will affect industries in Kitakyushu and Shimonoseki. First, ASEAN's rapid economic during the past five decades has made ASEAN a large market for Japanese goods, services, and firms. ASEAN has supported this growth by facilitating important economic and political dialogue in Southeast Asia and AEC2015 will likely reinforce this important role. Second, although ...

  10. Formerly utilized MED/AEC sites Remedial Action Program. Report of the decontamination of Jones Chemical Laboratory, Ryerson Physical Laboratory, and Eckhart Hall, the University of Chicago, Chicago, Illinois

    Energy Technology Data Exchange (ETDEWEB)

    Wynuveen, R.A.; Smith, W.H.; Sholeen, C.M.; Flynn, K.F.

    1984-08-01

    The US Department of Energy (DOE) has implemented a program to decontaminate radioactively contaminated sites that were formerly utilized by the Manhattan Engineer District (MED) and/or the Atomic Energy Commission (AEC) for activities that included handling of radioactive material. This program is referred to as the ''Formerly Utilized Sites Remedial Action Program'' (FUSRAP). Among these sites are Jones Chemical Laboratory, Ryerson Physical Laboratory, Kent Chemical Laboratory, and Eckhart Hall of The University of Chicago, Chicago, Illinois. Since 1977, the University of Chicago decontaminated Kent Chemical Laboratory as part of a facilities renovation program. All areas of Eckhart Hall, Ryerson Physical Laboratory, and Jones Chemical Laboratory that had been identified as contaminated in excess of current guidelines in the 1976-1977 surveys were decontaminated to levels where no contamination could be detected relative to natural backgrounds. All areas that required defacing to achieve this goal were restored to their original condition. The radiological evaluation of the sewer system, based primarily on the radiochemical analyses of sludge and water samples, indicated that the entire sewer system is potentially contaminated. While this evaluation was defined as part of this project, the decontamination of the sewer system was not included in the purview of this effort. The documentation included in this report substantiates the judgment that all contaminated areas identified in the earlier reports in the three structures included in the decontamination effort (Eckhart Hall, Ryerson Physical Laboratory, and Jones Chemical Laboratory) were cleaned to levels commensurate with release for unrestricted use.

  11. Formerly utilized MED/AEC sites Remedial Action Program. Report of the decontamination of Jones Chemical Laboratory, Ryerson Physical Laboratory, and Eckhart Hall, the University of Chicago, Chicago, Illinois

    International Nuclear Information System (INIS)

    Wynuveen, R.A.; Smith, W.H.; Sholeen, C.M.; Flynn, K.F.

    1984-08-01

    The US Department of Energy (DOE) has implemented a program to decontaminate radioactively contaminated sites that were formerly utilized by the Manhattan Engineer District (MED) and/or the Atomic Energy Commission (AEC) for activities that included handling of radioactive material. This program is referred to as the ''Formerly Utilized Sites Remedial Action Program'' (FUSRAP). Among these sites are Jones Chemical Laboratory, Ryerson Physical Laboratory, Kent Chemical Laboratory, and Eckhart Hall of The University of Chicago, Chicago, Illinois. Since 1977, the University of Chicago decontaminated Kent Chemical Laboratory as part of a facilities renovation program. All areas of Eckhart Hall, Ryerson Physical Laboratory, and Jones Chemical Laboratory that had been identified as contaminated in excess of current guidelines in the 1976-1977 surveys were decontaminated to levels where no contamination could be detected relative to natural backgrounds. All areas that required defacing to achieve this goal were restored to their original condition. The radiological evaluation of the sewer system, based primarily on the radiochemical analyses of sludge and water samples, indicated that the entire sewer system is potentially contaminated. While this evaluation was defined as part of this project, the decontamination of the sewer system was not included in the purview of this effort. The documentation included in this report substantiates the judgment that all contaminated areas identified in the earlier reports in the three structures included in the decontamination effort (Eckhart Hall, Ryerson Physical Laboratory, and Jones Chemical Laboratory) were cleaned to levels commensurate with release for unrestricted use

  12. Personality assessment inventory profile and predictors of elevations among dissociative disorder patients.

    Science.gov (United States)

    Stadnik, Ryan D; Brand, Bethany; Savoca, Angela

    2013-01-01

    Assessing patients with dissociative disorders (DD) using personality tests is difficult. On the Minnesota Multiphasic Personality Inventory-2 ( J. N. Butcher, W. G. Dahlstrom, J. R. Graham, A. Tellegen, & B. Kaemmer, 1989 ), DD patients often obtain elevations on multiple clinical scales as well as on validity scales that were thought to indicate exaggeration yet have been shown to be elevated among traumatized individuals, including those with DD. No research has been conducted to determine how DD patients score on the Personality Assessment Inventory (PAI; L. C. Morey, 1991 ), which includes the symptom exaggeration scale Negative Impression (NIM) and the malingering scales Malingering Index (MAL) and Rogers Discriminant Function (RDF). The goals of this study were to document the PAI profile of dissociative identity disorder (DID) and dissociative disorder not otherwise specified (DDNOS) patients and to determine how the validity and Schizophrenia scales are related to other PAI scales as well as dissociation. A total of 42 inpatients with DID or DDNOS were assessed on the PAI as well as the Dissociative Experiences Scale-II. The DID/DDNOS patients were elevated on many PAI scales, including NIM and, to a lesser extent, MAL, but not RDF. Dissociation scores significantly and uniquely predicted NIM scores above and beyond Depression and Borderline Features. In addition, after we controlled for MAL and RDF, dissociation was positively associated with NIM. In contrast, after we controlled for the other 2 scales, dissociation was not related to MAL and was negatively related to RDF, indicating that RDF and, to a lesser extent, MAL are better correlates of feigning in DD patients than NIM.

  13. Hotspots on Io During the Ganymede 2 Encounter

    Science.gov (United States)

    1996-01-01

    The Near Infrared Mapping Spectrometer (NIMS) on the Galileo spacecraft imaged Io at high spectral resolution at a range of 439,000 km (275,000 miles) during the G2 encounter on 6 September 1996. This image shows, on the right, Io as seen by NIMS, centered on 150 W longitude. The image on the left shows the same view point from Voyager data (from the encounters in 1979 and 1980). The NIMS image can be compared to the NIMS hotspot image from the G1 orbit (June 1996) to monitor changes on Io. The most dramatic feature of the G2 image is the hotspot at Malik Patera. Preliminary analysis of the data yields a temperature of at least 1000 K (727 C) for this hotspot, an increase of more than 300 K from the G1 encounter. In the overlap area of the G1 and G2 images all the hotspots seen during the G1 encounter are also seen in the G2 image. Other hotspots were seen, including one at the Pele plume origin site. This image is at the 4 micron band to best view the Malik hotspot. Most of the other hotspots are best seen at longer wavelengths. NIMS is continuing to observe Io to monitor volcanic activity throughout the Galileo mission.The Jet Propulsion Laboratory, Pasadena, CA manages the mission for NASA's Office of Space Science, Washington, DC.This image and other images and data received from Galileo are posted on the World Wide Web, on the Galileo mission home page at URL http://galileo.jpl.nasa.gov.

  14. Enhanced nonlinearity interval mapping scheme for high-performance simulation-optimization of watershed-scale BMP placement

    Science.gov (United States)

    Zou, Rui; Riverson, John; Liu, Yong; Murphy, Ryan; Sim, Youn

    2015-03-01

    Integrated continuous simulation-optimization models can be effective predictors of a process-based responses for cost-benefit optimization of best management practices (BMPs) selection and placement. However, practical application of simulation-optimization model is computationally prohibitive for large-scale systems. This study proposes an enhanced Nonlinearity Interval Mapping Scheme (NIMS) to solve large-scale watershed simulation-optimization problems several orders of magnitude faster than other commonly used algorithms. An efficient interval response coefficient (IRC) derivation method was incorporated into the NIMS framework to overcome a computational bottleneck. The proposed algorithm was evaluated using a case study watershed in the Los Angeles County Flood Control District. Using a continuous simulation watershed/stream-transport model, Loading Simulation Program in C++ (LSPC), three nested in-stream compliance points (CP)—each with multiple Total Maximum Daily Loads (TMDL) targets—were selected to derive optimal treatment levels for each of the 28 subwatersheds, so that the TMDL targets at all the CP were met with the lowest possible BMP implementation cost. Genetic Algorithm (GA) and NIMS were both applied and compared. The results showed that the NIMS took 11 iterations (about 11 min) to complete with the resulting optimal solution having a total cost of 67.2 million, while each of the multiple GA executions took 21-38 days to reach near optimal solutions. The best solution obtained among all the GA executions compared had a minimized cost of 67.7 million—marginally higher, but approximately equal to that of the NIMS solution. The results highlight the utility for decision making in large-scale watershed simulation-optimization formulations.

  15. Opportunities in independent gas storage

    International Nuclear Information System (INIS)

    Daniel, R.

    1999-01-01

    The range of business opportunities currently available for the midstream oil and gas business were discussed with particular focus on storage opportunities. Alberta Energy Co. (AEC) Ltd.'s two midstream business units include AEC Pipelines and Gas Processing, and AEC Storage and Hub Services. These two businesses provide the company with good investment returns, stable cash flow, and some significant strategic synergies with their exploration and production businesses. In 1988, the AECO C Hub in southeastern Alberta was created as an outgrowth of AEC's gas production operations on the Suffield block, where they had depleted gas reservoirs with high rock quality suitable for high deliverability storage. With the AECO C Hub, AEC was able to offer firm storage contracts of from 1 to 20 years, and to introduce short term interruptible parking and lending services, title exchange, a spot price index for greater price discovery, and an electronic nomination system. AEC is currently completing construction of their second commercial storage facility, the Wild Goose project, in northern California. D ebottlenecking' the Western Canada supply basin should provide additional opportunities for further expansion not only for AEC but also for other midstream service providers. Opportunities are especially available in the areas of new storage facilities to serve location-specific needs, replacement of declining storage capacity, replacement of retiring facilities, technological optimization of existing facilities, more flexible, higher deliverability facilities and commercial optimization of existing facilities. A map of the hubs and market centres of North America are included. 5 figs

  16. Experiment of amnion epithelial cell suspension liquid used for acute rabbit corneal alkali burn

    Directory of Open Access Journals (Sweden)

    Yan-Yan Zhang

    2017-10-01

    Full Text Available AIM: To investigate the effects of amnion epithelial cell(AECsuspension liquid on the biological behavior of the rabbit's corneal epithelium, combined with the in vitro and in vivo experiments. METHODS: The rabbit's corneal epithelium were cultured in the lower chamber of transwell, and AEC suspension liquid was dropwised in the upper chamber. There was only culture medium in the upper chamber of the control group. The proliferation of rabbit's corneal epithelium was observed with CCK-8 automated colorimetry and the expression of PCNA was detected by immunocytochemistry. We used the scratch wound assay to detect the migration of corneal epithelial cell(CEC. The in vivo models were established by placing a 10mm diameter corneal trephine in the center of the cornea, within 1mol/L NaOH for 1min. We divided those into three groups: treatment group of AEC suspension liquid eye drop, AEC suspension liquid subconjunctival injection and the control group without any treatment. Using the slit-lamp biomicroscope and fluorescence staining to observe the cornea per week. After 28d we took the eyeballs with the HE staining. The expression of VEGF was detected by immunohistochemistry. RESULTS: The activity of CEC with AEC treatment was much higher than the control group(PPIn vivo, the inflammation of the corneal and the CNV of the AEC group were all significantly reduced compared with the control group(PPCONCLUSION: AEC suspension liquid can promote the proliferation and migration of the rabbit's corneal epithelium. The potential of AEC suspension liquid as a therapy for acute corneal alkali burn.

  17. Adsorptive stripping voltammetric determination of nitroimidazole derivative on multiwalled carbon nanotube modified electrodes: influence of size and functionalization of nanotubes

    Energy Technology Data Exchange (ETDEWEB)

    Jara-Ulloa, Paola; Canete-Rosales, Paulina; Nunez-Vergara, Luis J; Squella, Juan A., E-mail: asquella@ciq.uchile.c [University of Chile, Santiago (Chile). Chemical and Pharmaceutical Sciences Faculty. Bioelectrochemistry Lab.

    2011-07-01

    1-Methyl-4-nitro-2-bromine methylimidazole (4-NimMeBr), was electrochemically reduced on mercury, glassy carbon and multiwalled carbon nanotubes (MWCNT) modified electrodes. 4-NimMeBr was adsorbed on the MWCNT modified electrode thus permitting the implementation of an adsorptive stripping voltammetric (ASV) method. We have used 4-NimMeBr as a prototype electroactive nitro compound to study the effect of both the size of the nanotubes and its functionalization by oxidation. The oxidized MWCNT forms better dispersions than the non-oxidized, producing electrode surface with higher density of MWCNT as was determined by electrochemical mapping using scanning electrochemical microscopy (SECM). Under the optimized conditions, the peak current was proportional to the concentration of 4-NimMeBr in the range of 10{sup -6} mol L{sup -1} to 10{sup -4} mol L{sup -1} with detection and quantification limits of 4.41 x 10{sup -6} mol L{sup -1} and 6.21 x 10{sup -6} mol L{sup -1}, respectively. The sensibility of bare electrode was 0.01 {mu}A per mmol L{sup -1}, which was lower than the value of 5.34 and 6.97 mA per mmol L{sup -1} obtained using short and large oxidized MWCNT, respectively. (author)

  18. Recent financial crisis and business perspective of Greek bank subsidiaries in Serbia

    Directory of Open Access Journals (Sweden)

    Ljumović Isidora

    2016-01-01

    Full Text Available Greece was one of the Eurozone countries that was hit the hardest by the crisis and there is a real threat that the risk overflow from the Greece home markets could have negative consequences on the activities of their subsidiaries in Serbia since they account for 14% of total assets of the banking sector in Serbia. The initial reasons for entering the Serbian market were versatile, the most important ones being the high interest margins, untapped debt potential of the corporate and retail sectors and a search for new clients. The data about the performance of Greek bank subsidiaries are mixed. The ROAA and ROAE data show that they are below average, but had a positive trend before the crisis. On the other hand, the data on the net interest margin (NIM show that before crisis the Greek subsidiaries had NIM above the industry average. After the crisis, the NIM decreased, but most of the banks are still above the average. Negative profitability figures mean that a bank is unable to generate income (net interest income or other operating income to the level necessary to cover the expenses, even though the NIM of Greek bank subsidiaries is above the banking sector average.

  19. Structural basis for the Nanos-mediated recruitment of the CCR4-NOT complex and translational repression.

    Science.gov (United States)

    Bhandari, Dipankar; Raisch, Tobias; Weichenrieder, Oliver; Jonas, Stefanie; Izaurralde, Elisa

    2014-04-15

    The RNA-binding proteins of the Nanos family play an essential role in germ cell development and survival in a wide range of metazoan species. They function by suppressing the expression of target mRNAs through the recruitment of effector complexes, which include the CCR4-NOT deadenylase complex. Here, we show that the three human Nanos paralogs (Nanos1-3) interact with the CNOT1 C-terminal domain and determine the structural basis for the specific molecular recognition. Nanos1-3 bind CNOT1 through a short CNOT1-interacting motif (NIM) that is conserved in all vertebrates and some invertebrate species. The crystal structure of the human Nanos1 NIM peptide bound to CNOT1 reveals that the peptide opens a conserved hydrophobic pocket on the CNOT1 surface by inserting conserved aromatic residues. The substitutions of these aromatic residues in the Nanos1-3 NIMs abolish binding to CNOT1 and abrogate the ability of the proteins to repress translation. Our findings provide the structural basis for the recruitment of the CCR4-NOT complex by vertebrate Nanos, indicate that the NIMs are the major determinants of the translational repression mediated by Nanos, and identify the CCR4-NOT complex as the main effector complex for Nanos function.

  20. Mitochondrial catalase overexpressed transgenic mice are protected against lung fibrosis in part via preventing alveolar epithelial cell mitochondrial DNA damage.

    Science.gov (United States)

    Kim, Seok-Jo; Cheresh, Paul; Jablonski, Renea P; Morales-Nebreda, Luisa; Cheng, Yuan; Hogan, Erin; Yeldandi, Anjana; Chi, Monica; Piseaux, Raul; Ridge, Karen; Michael Hart, C; Chandel, Navdeep; Scott Budinger, G R; Kamp, David W

    2016-12-01

    Alveolar epithelial cell (AEC) injury and mitochondrial dysfunction are important in the development of lung fibrosis. Our group has shown that in the asbestos exposed lung, the generation of mitochondrial reactive oxygen species (ROS) in AEC mediate mitochondrial DNA (mtDNA) damage and apoptosis which are necessary for lung fibrosis. These data suggest that mitochondrial-targeted antioxidants should ameliorate asbestos-induced lung. To determine whether transgenic mice that express mitochondrial-targeted catalase (MCAT) have reduced lung fibrosis following exposure to asbestos or bleomycin and, if so, whether this occurs in association with reduced AEC mtDNA damage and apoptosis. Crocidolite asbestos (100µg/50µL), TiO 2 (negative control), bleomycin (0.025 units/50µL), or PBS was instilled intratracheally in 8-10 week-old wild-type (WT - C57Bl/6J) or MCAT mice. The lungs were harvested at 21d. Lung fibrosis was quantified by collagen levels (Sircol) and lung fibrosis scores. AEC apoptosis was assessed by cleaved caspase-3 (CC-3)/Surfactant protein C (SFTPC) immunohistochemistry (IHC) and semi-quantitative analysis. AEC (primary AT2 cells from WT and MCAT mice and MLE-12 cells) mtDNA damage was assessed by a quantitative PCR-based assay, apoptosis was assessed by DNA fragmentation, and ROS production was assessed by a Mito-Sox assay. Compared to WT, crocidolite-exposed MCAT mice exhibit reduced pulmonary fibrosis as measured by lung collagen levels and lung fibrosis score. The protective effects in MCAT mice were accompanied by reduced AEC mtDNA damage and apoptosis. Similar findings were noted following bleomycin exposure. Euk-134, a mitochondrial SOD/catalase mimetic, attenuated MLE-12 cell DNA damage and apoptosis. Finally, compared to WT, asbestos-induced MCAT AT2 cell ROS production was reduced. Our finding that MCAT mice have reduced pulmonary fibrosis, AEC mtDNA damage and apoptosis following exposure to asbestos or bleomycin suggests an important role

  1. OPPORTUNITIES AND CHALLENGES FOR MICRO-SMALL AND MEDIUM BUSINESS IN INDONESIA FACING ASEAN ECONOMIC COMMUNITY

    OpenAIRE

    Raden Aswin Rahadi

    2016-01-01

    This research is a part of a continuous study to analyze the opportunities and challenges for micro-small and medium business in Indonesia when facing ASEAN Economic Community (AEC) in 2016. It has its own uniqueness, as it will combine the point of view between current business owners and current literature study synthesis on business perception towards AEC. Ten business owners have been interviewed. The results suggested AEC provides challenges for the business owners, particularly in terms...

  2. AEC controlled area safety program

    Energy Technology Data Exchange (ETDEWEB)

    Hendricks, D W [Nevada Operations Office, Atomic Energy Commission, Las Vegas, NV (United States)

    1969-07-01

    The detonation of underground nuclear explosives and the subsequent data recovery efforts require a comprehensive pre- and post-detonation safety program for workers within the controlled area. The general personnel monitoring and environmental surveillance program at the Nevada Test Site are presented. Some of the more unusual health-physics aspects involved in the operation of this program are also discussed. The application of experience gained at the Nevada Test Site is illustrated by description of the on-site operational and safety programs established for Project Gasbuggy. (author)

  3. AEC controlled area safety program

    International Nuclear Information System (INIS)

    Hendricks, D.W.

    1969-01-01

    The detonation of underground nuclear explosives and the subsequent data recovery efforts require a comprehensive pre- and post-detonation safety program for workers within the controlled area. The general personnel monitoring and environmental surveillance program at the Nevada Test Site are presented. Some of the more unusual health-physics aspects involved in the operation of this program are also discussed. The application of experience gained at the Nevada Test Site is illustrated by description of the on-site operational and safety programs established for Project Gasbuggy. (author)

  4. Index to AEC Information Booklets

    Energy Technology Data Exchange (ETDEWEB)

    None

    1978-01-01

    The U. S. Atomic Energy Commission publishes a series of information booklets for the general public. These booklets explain many aspects of nuclear science. Because these booklets cover such a variety of scientific fields, this index was prepared to help the reader find quickly those booklets that contain the information he needs.

  5. Summary history of domestic uranium procurement under US Atomic Energy Commission contracts. Final report

    International Nuclear Information System (INIS)

    Albrethsen, H. Jr.; McGinley, F.E.

    1982-09-01

    During the period 1947 through 1970, the Atomic Energy Commission (AEC) fostered the rapid development and expansion of the domestic uranium mining and milling industry by providing a market for uranium. Some thirty-two mills were constructed during that period to produce U 3 O 8 concentrates for sale to the AEC. In addition, there were various pilot plants, concentrators, upgraders, heap leach, and solution mining facilities that operated during the period. The purpose of this report is to compile a short narrative history of the AEC's uranium concentrate procurement program and to describe briefly each of the operations that produced uranium for sale to the AEC. Contractual arrangements are described and data are given on quantities of U 3 O 8 purchased and prices paid. Similar data are included for V 2 O 5 , where applicable. Mill and other plant operating data were also compiled from old AEC records. These latter data were provided by the companies, as a contractual requirement, during the period of operation under AEC contracts. Additionally, an effort was made to determine the present status of each facility by reference to other recently published reports. No sites were visited nor were the individual reports reviewed by the companies, many of which no longer exist. The authors relied almost entirely on published information for descriptions of facilities and milling processes utilized

  6. Immunological compatibility status of placenta-derived stem cells is mediated by scaffold 3D structure.

    Science.gov (United States)

    Azizian, Sara; Khatami, Fatemeh; Modaresifar, Khashayar; Mosaffa, Nariman; Peirovi, Habibollah; Tayebi, Lobat; Bahrami, Soheyl; Redl, Heinz; Niknejad, Hassan

    2018-02-23

    Placenta-derived amniotic epithelial cells (AECs), a great cell source for tissue engineering and stem cell therapy, are immunologically inert in their native state; however, immunological changes in these cells after culture and differentiation have challenged their applications. The aim of this study was to investigate the effect of 2D and 3D scaffolds on human lymphocyte antigens (HLA) expression by AECs. The effect of different preparation parameters including pre-freezing time and temperature was evaluated on 3D chitosan-gelatine scaffolds properties. Evaluation of MHC class I, HLA-DR and HLA-G expression in AECs after 7 d culture on 2D bed and 3D scaffold of chitosan-gelatine showed that culture of AECs on the 2D substrate up-regulated MHC class I and HLA-DR protein markers on AECs surface and down-regulated HLA-G protein. In contrast, 3D scaffold did not increase protein expression of MHC class I and HLA-DR. Moreover, HLA-G protein expression remained unchanged in 3D culture. These results confirm that 3D scaffold can remain AECs in their native immunological state and modification of physical properties of the scaffold is a key regulator of immunological markers at the gene and protein expression levels; a strategy which circumvents rejection challenge of amniotic stem cells to be translated into the clinic.

  7. Hypoglycemic and anti-lipemic effects of the aqueous extract from Cissus sicyoides

    Science.gov (United States)

    Viana, Glauce SB; Medeiros, Ana Carolina C; Lacerda, Ana Michelle R; Leal, L Kalyne AM; Vale, Tiago G; Matos, F José de Abreu

    2004-01-01

    Background Cissus sicyoides (Vitaceae) is a medicinal plant popularly known in Brazil as "cipó-pucá, anil-trepador, cortina, and insulina". The plant is used in several diseases, including rheumatism, epilepsy, stroke and also in the treatment of diabetes. In the present work, we studied the hypoglycemic and anti-lipemic effects of the aqueous extract prepared from fresh leaves of the plant (AECS), in the model of alloxan-induced diabetes in rats. In addition, hepatic enzyme levels were also determined. Results Results showed that the daily treatment of diabetic rats with AECS for 7 days (100 and 200 mg/kg, p.o.) significantly decreased blood glucose levels in 25 and 22% respectively, as compared to the same groups before AECS treatment. No significant changes were seen in control diabetic rats before (48 h after alloxan administration) and after distilled water treatment. While no changes were seen in total cholesterol levels, a significant decrease was observed in plasma triglyceride levels, in the alloxan-induced diabetic rats after AECS treatment with both doses, as compared to the same groups before treatment. Significant decreases in blood glucose (25%) and triglyceride levels (48%) were also observed in the alloxan-induced diabetic rats after 4 days treatment with AECS (200 mg/kg, p.o.). Aspartate (AST) and alanine (ALT) aminotransferases levels, in diabetic controls and AECS-treated rats, were in the range of reference values presented by normal rats. Conclusions The results justify the popular use of C. sicyoides, pointing out to the potential benefit of the plant aqueous extract (AECS) in alternative medicine, in the treatment of type 2 diabetes mellitus. PMID:15182373

  8. Quantitative Analysis of Proteome Modulations in Alveolar Epithelial Type II Cells in Response to Pulmonary Aspergillus fumigatus Infection.

    Science.gov (United States)

    Seddigh, Pegah; Bracht, Thilo; Molinier-Frenkel, Válerie; Castellano, Flavia; Kniemeyer, Olaf; Schuster, Marc; Weski, Juliane; Hasenberg, Anja; Kraus, Andreas; Poschet, Gernot; Hager, Thomas; Theegarten, Dirk; Opitz, Christiane A; Brakhage, Axel A; Sitek, Barbara; Hasenberg, Mike; Gunzer, Matthias

    2017-12-01

    The ubiquitous mold Aspergillus fumigatus threatens immunosuppressed patients as inducer of lethal invasive aspergillosis. A. fumigatus conidia are airborne and reach the alveoli, where they encounter alveolar epithelial cells (AEC). Previous studies reported the importance of the surfactant-producing AEC II during A. fumigatus infection via in vitro experiments using cell lines. We established a negative isolation protocol yielding untouched primary murine AEC II with a purity >90%, allowing ex vivo analyses of the cells, which encountered the mold in vivo By label-free proteome analysis of AEC II isolated from mice 24h after A. fumigatus or mock infection we quantified 2256 proteins and found 154 proteins to be significantly differentially abundant between both groups (ANOVA p value ≤ 0.01, ratio of means ≥1.5 or ≤0.67, quantified with ≥2 peptides). Most of these proteins were higher abundant in the infected condition and reflected a comprehensive activation of AEC II on interaction with A. fumigatus This was especially represented by proteins related to oxidative phosphorylation, hence energy production. However, the most strongly induced protein was the l-amino acid oxidase (LAAO) Interleukin 4 induced 1 (IL4I1) with a 42.9 fold higher abundance (ANOVA p value 2.91 -10 ). IL4I1 has previously been found in B cells, macrophages, dendritic cells and rare neurons. Increased IL4I1 abundance in AEC II was confirmed by qPCR, Western blot and immunohistology. Furthermore, A. fumigatus infected lungs showed high levels of IL4I1 metabolic products. Importantly, higher IL4I1 abundance was also confirmed in lung tissue from human aspergilloma. Because LAAO are key enzymes for bactericidal product generation, AEC II might actively participate in pathogen defense. We provide insights into proteome changes of primary AEC II thereby opening new avenues to analyze the molecular changes of this central lung cell on infectious threats. Data are available via Proteome

  9. Comparison of Measured and Estimated CT Organ Doses for Modulated and Fixed Tube Current:: A Human Cadaver Study.

    Science.gov (United States)

    Padole, Atul; Deedar Ali Khawaja, Ranish; Otrakji, Alexi; Zhang, Da; Liu, Bob; Xu, X George; Kalra, Mannudeep K

    2016-05-01

    The aim of this study was to compare the directly measured and the estimated computed tomography (CT) organ doses obtained from commercial radiation dose-tracking (RDT) software for CT performed with modulated tube current or automatic exposure control (AEC) technique and fixed tube current (mAs). With the institutional review board (IRB) approval, the ionization chambers were surgically implanted in a human cadaver (88 years old, male, 68 kg) in six locations such as liver, stomach, colon, left kidney, small intestine, and urinary bladder. The cadaver was scanned with routine abdomen pelvis protocol on a 128-slice, dual-source multidetector computed tomography (MDCT) scanner using both AEC and fixed mAs. The effective and quality reference mAs of 100, 200, and 300 were used for AEC and fixed mAs, respectively. Scanning was repeated three times for each setting, and measured and estimated organ doses (from RDT software) were recorded (N = 3*3*2 = 18). Mean CTDIvol for AEC and fixed mAs were 4, 8, 13 mGy and 7, 14, 21 mGy, respectively. The most estimated organ doses were significantly greater (P < 0.01) than the measured organ doses for both AEC and fixed mAs. At AEC, the mean estimated organ doses (for six organs) were 14.7 mGy compared to mean measured organ doses of 12.3 mGy. Similarly, at fixed mAs, the mean estimated organ doses (for six organs) were 24 mGy compared to measured organ doses of 22.3 mGy. The differences among the measured and estimated organ doses were higher for AEC technique compared to the fixed mAs for most organs (P < 0.01). The most CT organ doses estimated from RDT software are greater compared to directly measured organ doses, particularly when AEC technique is used for CT scanning. Copyright © 2016 The Association of University Radiologists. Published by Elsevier Inc. All rights reserved.

  10. Low-dose computed tomography scans with automatic exposure control for patients of different ages undergoing cardiac PET/CT and SPECT/CT.

    Science.gov (United States)

    Yang, Ching-Ching; Yang, Bang-Hung; Tu, Chun-Yuan; Wu, Tung-Hsin; Liu, Shu-Hsin

    2017-06-01

    This study aimed to evaluate the efficacy of automatic exposure control (AEC) in order to optimize low-dose computed tomography (CT) protocols for patients of different ages undergoing cardiac PET/CT and single-photon emission computed tomography/computed tomography (SPECT/CT). One PET/CT and one SPECT/CT were used to acquire CT images for four anthropomorphic phantoms representative of 1-year-old, 5-year-old and 10-year-old children and an adult. For the hybrid systems investigated in this study, the radiation dose and image quality of cardiac CT scans performed with AEC activated depend mainly on the selection of a predefined image quality index. Multiple linear regression methods were used to analyse image data from anthropomorphic phantom studies to investigate the effects of body size and predefined image quality index on CT radiation dose in cardiac PET/CT and SPECT/CT scans. The regression relationships have a coefficient of determination larger than 0.9, indicating a good fit to the data. According to the regression models, low-dose protocols using the AEC technique were optimized for patients of different ages. In comparison with the standard protocol with AEC activated for adult cardiac examinations used in our clinical routine practice, the optimized paediatric protocols in PET/CT allow 32.2, 63.7 and 79.2% CT dose reductions for anthropomorphic phantoms simulating 10-year-old, 5-year-old and 1-year-old children, respectively. The corresponding results for cardiac SPECT/CT are 8.4, 51.5 and 72.7%. AEC is a practical way to reduce CT radiation dose in cardiac PET/CT and SPECT/CT, but the AEC settings should be determined properly for optimal effect. Our results show that AEC does not eliminate the need for paediatric protocols and CT examinations using the AEC technique should be optimized for paediatric patients to reduce the radiation dose as low as reasonably achievable.

  11. Autonomy in euthyroid goitre: Precursor of non-immunogenic hyperthyroidism in an area of iodine deficiency

    International Nuclear Information System (INIS)

    Emrich, D.; Schicha, H.

    1984-01-01

    There is evidence that in an area of iodine deficiency NIM-HY exists to a considerable percentage, probably originating from euthyroid goitre with autonomy, especially if iodine intake is suddenly increased. Separation of IM-HY and NIM-HY is possible with a probability of 90% by clinical criteria and available laboratory investigations. This might be important not only from a pathophysiological point of view but also for diagnosis and selection of the kind of therapy. (orig.)

  12. Analisis Faktor-Faktor Yang Mempengaruhi Profitabilitas Perbankan

    Directory of Open Access Journals (Sweden)

    Wawan Prasetyo

    2015-03-01

    Full Text Available This research result shows that ratio of NPL, BOPO, and NIM influenced the profitability partially. But simultaneously, ratio of CAR, NPL, BOPO, LDR, and NIM influenced to the profitability. Based the research result, it is obtained the conclusion that if NIM in interest income over productive asset has an improvement, then BOPO in the operational cost that spent by related bank will be more efficient. And if LDR in serving and distributing the fund for people can be fulfilled, then NPL in repreship can be controlled and will improve capital adequacy to the CAR, thus it can improve bank profitability. Based on this research, it can be suggested to Bank BUMN Persero that it expected to be able to keep bank stability in order to make bank intermediate function can be running well, thus profitability as orientation of bank established can be fulfilled as expected target.

  13. Inhalation carcinogenicity study with nickel metal powder in Wistar rats

    International Nuclear Information System (INIS)

    Oller, Adriana R.; Kirkpatrick, Daniel T.; Radovsky, Ann; Bates, Hudson K.

    2008-01-01

    Epidemiological studies of nickel refinery workers have demonstrated an association between increased respiratory cancer risk and exposure to certain nickel compounds (later confirmed in animal studies). However, the lack of an association found in epidemiological analyses for nickel metal remained unconfirmed for lack of robust animal inhalation studies. In the present study, Wistar rats were exposed by whole-body inhalation to 0, 0.1, 0.4, and 1.0 mg Ni/m 3 nickel metal powder (MMAD = 1.8 μm, GSD = 2.4 μm) for 6 h/day, 5 days/week for up to 24 months. A subsequent six-month period without exposures preceded the final euthanasia. High mortality among rats exposed to 1.0 mg Ni/m 3 nickel metal resulted in the earlier termination of exposures in this group. The exposure level of 0.4 mg Ni/m 3 was established as the MTD for the study. Lung alterations associated with nickel metal exposure included alveolar proteinosis, alveolar histiocytosis, chronic inflammation, and bronchiolar-alveolar hyperplasia. No increased incidence of neoplasm of the respiratory tract was observed. Adrenal gland pheochromocytomas (benign and malignant) in males and combined cortical adenomas/carcinomas in females were induced in a dose-dependent manner by the nickel metal exposure. The incidence of pheochromocytomas was statistically increased in the 0.4 mg Ni/m 3 male group. Pheochromocytomas appear to be secondary to the lung toxicity associated with the exposure rather than being related to a direct nickel effect on the adrenal glands. The incidence of cortical tumors among 0.4 mg Ni/m 3 females, although statistically higher compared to the concurrent controls, falls within the historical control range; therefore, in the present study, this tumor is of uncertain relationship to nickel metal exposure. The lack of respiratory tumors in the present animal study is consistent with the findings of the epidemiological studies

  14. Non-indigenous macroinvertebrate species in Lithuanian fresh waters, Part 2: Macroinvertebrate assemblage deviation from naturalness in lotic systems and the consequent potential impacts on ecological quality assessment

    Directory of Open Access Journals (Sweden)

    Arbačiauskas K.

    2011-12-01

    Full Text Available The biological pressure represented by non-indigenous macroinvertebrate species (NIMS should be addressed in the implementation of EU Water Framework Directive as this can have a direct impact on the ’naturalness’ of the invaded macroinvertebrate assemblage. The biocontamination concept allows assessment of this deviation from naturalness, by evaluation of abundance and disparity contamination of an assemblage. This study aimed to assess the biocontamination of macroinvertebrate assemblages in Lithuanian rivers, thereby revealing the most high-impact non-indigenous species, and to explore the relationship between biocontamination and conventional metrics of ecological quality. Most of the studied rivers appeared to be impacted by NIMS. The amphipods Pontogammarus robustoides, Chelicorophium curvispinum and snail Litoglyphus naticoides were revealed as high-impact NIMS for Lithuanian lotic systems. Metrics of ecological quality which largely depend upon the richness of indicator taxa, such as the biological monitoring working party (BMWP score and Ephemeroptera/Plecoptera/Trichoptera (EPT taxa number, were negatively correlated with biocontamination, implying they could provide unreliable ecological quality estimates when NIMS are present. Routine macroinvertebrate water quality monitoring data are sufficient for generation of the biocontamination assessment and thus can provide supplementary information, with minimal extra expense or effort. We therefore recommend that biocontamination assessment is included alongside established methods for gauging biological and chemical water quality.

  15. Hierarchical Canopy Dynamics of Electrolyte-Doped Nanoscale Ionic Materials

    KAUST Repository

    Jespersen, Michael L.

    2013-12-23

    Nanoscale ionic materials (NIMs) are organic-inorganic hybrids prepared from ionically functionalized nanoparticles (NP) neutralized by oligomeric polymer counterions. NIMs are designed to behave as liquids under ambient conditions in the absence of solvent and have no volatile organic content, making them useful for a number of applications. We have used nuclear magnetic resonance relaxation and pulsed-field gradient NMR to probe local and collective canopy dynamics in NIMs based on 18-nm silica NPs with a covalently bound anionic corona, neutralized by amine-terminated ethylene oxide/propylene oxide block copolymers. The NMR relaxation studies show that the nanosecond-scale canopy dynamics depend on the degree of neutralization, the canopy radius of gyration, and crowding at the ionically modified NP surface. Two canopy populations are observed in the diffusion experiments, demonstrating that one fraction of the canopy is bound to the NP surface on the time scale (milliseconds) of the diffusion experiment and is surrounded by a more mobile layer of canopy that is unable to access the surface due to molecular crowding. The introduction of electrolyte ions (Na+ or Mg2+) screens the canopy-corona electrostatic interactions, resulting in a reduced bulk viscosity and faster canopy exchange. The magnitude of the screening effect depends upon ion concentration and valence, providing a simple route for tuning the macroscopic properties of NIMs. © 2013 American Chemical Society.

  16. Hierarchical Canopy Dynamics of Electrolyte-Doped Nanoscale Ionic Materials

    KAUST Repository

    Jespersen, Michael L.; Mirau, Peter A.; von Meerwall, Ernst D.; Koerner, Hilmar; Vaia, Richard A.; Fernandes, Nikhil J.; Giannelis, Emmanuel P.

    2013-01-01

    Nanoscale ionic materials (NIMs) are organic-inorganic hybrids prepared from ionically functionalized nanoparticles (NP) neutralized by oligomeric polymer counterions. NIMs are designed to behave as liquids under ambient conditions in the absence of solvent and have no volatile organic content, making them useful for a number of applications. We have used nuclear magnetic resonance relaxation and pulsed-field gradient NMR to probe local and collective canopy dynamics in NIMs based on 18-nm silica NPs with a covalently bound anionic corona, neutralized by amine-terminated ethylene oxide/propylene oxide block copolymers. The NMR relaxation studies show that the nanosecond-scale canopy dynamics depend on the degree of neutralization, the canopy radius of gyration, and crowding at the ionically modified NP surface. Two canopy populations are observed in the diffusion experiments, demonstrating that one fraction of the canopy is bound to the NP surface on the time scale (milliseconds) of the diffusion experiment and is surrounded by a more mobile layer of canopy that is unable to access the surface due to molecular crowding. The introduction of electrolyte ions (Na+ or Mg2+) screens the canopy-corona electrostatic interactions, resulting in a reduced bulk viscosity and faster canopy exchange. The magnitude of the screening effect depends upon ion concentration and valence, providing a simple route for tuning the macroscopic properties of NIMs. © 2013 American Chemical Society.

  17. Structural basis for the Nanos-mediated recruitment of the CCR4–NOT complex and translational repression

    Science.gov (United States)

    Bhandari, Dipankar; Raisch, Tobias; Weichenrieder, Oliver; Jonas, Stefanie; Izaurralde, Elisa

    2014-01-01

    The RNA-binding proteins of the Nanos family play an essential role in germ cell development and survival in a wide range of metazoan species. They function by suppressing the expression of target mRNAs through the recruitment of effector complexes, which include the CCR4–NOT deadenylase complex. Here, we show that the three human Nanos paralogs (Nanos1–3) interact with the CNOT1 C-terminal domain and determine the structural basis for the specific molecular recognition. Nanos1–3 bind CNOT1 through a short CNOT1-interacting motif (NIM) that is conserved in all vertebrates and some invertebrate species. The crystal structure of the human Nanos1 NIM peptide bound to CNOT1 reveals that the peptide opens a conserved hydrophobic pocket on the CNOT1 surface by inserting conserved aromatic residues. The substitutions of these aromatic residues in the Nanos1–3 NIMs abolish binding to CNOT1 and abrogate the ability of the proteins to repress translation. Our findings provide the structural basis for the recruitment of the CCR4–NOT complex by vertebrate Nanos, indicate that the NIMs are the major determinants of the translational repression mediated by Nanos, and identify the CCR4–NOT complex as the main effector complex for Nanos function. PMID:24736845

  18. Detection and Sizing of Fatigue Cracks in Steel Welds with Advanced Eddy Current Techniques

    Science.gov (United States)

    Todorov, E. I.; Mohr, W. C.; Lozev, M. G.

    2008-02-01

    Butt-welded specimens were fatigued to produce cracks in the weld heat-affected zone. Advanced eddy current (AEC) techniques were used to detect and size the cracks through a coating. AEC results were compared with magnetic particle and phased-array ultrasonic techniques. Validation through destructive crack measurements was also conducted. Factors such as geometry, surface treatment, and crack tightness interfered with depth sizing. AEC inspection techniques have the potential of providing more accurate and complete sizing flaw data for manufacturing and in-service inspections.

  19. Spinocerebellar ataxias Ataxias espinocerebelares

    Directory of Open Access Journals (Sweden)

    Hélio A.G. Teive

    2009-12-01

    Full Text Available Spinocerebellar ataxias (SCAs constitute a heterogeneous group of neurodegenerative diseases characterized by progressive cerebellar ataxia in association with some or all of the following conditions: ophthalmoplegia, pyramidal signs, movement disorders, pigmentary retinopathy, peripheral neuropathy, cognitive dysfunction and dementia. OBJECTIVE: To carry out a clinical and genetic review of the main types of SCA. METHOD: The review was based on a search of the PUBMED and OMIM databases. RESULTS: Thirty types of SCAs are currently known, and 16 genes associated with the disease have been identified. The most common types are SCA type 3, or Machado-Joseph disease, SCA type 10 and SCA types 7, 2, 1 and 6. SCAs are genotypically and phenotypically very heterogeneous. A clinical algorithm can be used to distinguish between the different types of SCAs. CONCLUSIONS: Detailed clinical neurological examination of SCA patients can be of great help when assessing them, and the information thus gained can be used in an algorithm to screen patients before molecular tests to investigate the correct etiology of the disease are requested.As ataxias espinocerebelares (AECs compreendem um grupo heterogeneo de enfermidades neurodegenerativas, que se caracterizam pela presença de ataxia cerebelar progressiva, associada de forma variada com oftalmoplegia, sinais piramidais, distúrbios do movimento, retinopatia pigmentar, neuropatia periférica, disfunção cognitiva e demência. OBJETIVO: Realizar uma revisão clínico-genética dos principais tipos de AECs. MÉTODO: A revisão foi realizada através da pesquisa pelo sistema do PUBMED e do OMIM. RESULTADOS: Na atualidade existem cerca de 30 tipos de AECs, com a descoberta de 16 genes. Os tipos mais comuns são a AEC tipo 3, ou doença de Machado-Joseph, a AEC tipo 10, e as AECs tipo 7, 2 1, e 6. As AECs apresentam grande heterogeneidade genotípica e fenotípica. Pode-se utilizar um algoritmo clínico para a

  20. Material d'estudi de psicofarmacologia

    OpenAIRE

    Moya Albiol, Luis

    2012-01-01

    Material d'estudi de psicofarmacologia: Delimitació conceptual i desenvolupament històric de la psicofarmacologia. Neurobiologia dels trastorns mentals. Conceptes bàsics en psicofarmacologia. Metodologia i tècniques d’investigació en psicofarmacologia. Bases biològiques dels trastorns de l’estat d’ànim. Antidepressius i estabilitzadors de l’estat d’ànim. Bases biològiques de l’ansietat. Ansiolítics i hipnòtics. Tractaments farmacològics per el trastorn obsessivo-compu...

  1. Gate-keeper module for TANSY-KM5

    International Nuclear Information System (INIS)

    Rydz, R.; Norberg, L.; Urholm, L.; Grosshoeg, G.

    1991-01-01

    The purpose of the Gate-keeper is the control of the RDCs, the ADCs, and the constant fraction discriminator. The Gate-keeper synchronizes the units and ensures that the data taking is clean and not intermixed with other events. There are six Gate-Keepers in the system, one for each proton detector. All input circuits are designed to accept TTL as well as negative NIM signals. The output is 50 ohm TTL or negative NIM as defined by internal jumpers

  2. CT dose reduction using Automatic Exposure Control and iterative reconstruction: A chest paediatric phantoms study.

    Science.gov (United States)

    Greffier, Joël; Pereira, Fabricio; Macri, Francesco; Beregi, Jean-Paul; Larbi, Ahmed

    2016-04-01

    To evaluate the impact of Automatic Exposure Control (AEC) on radiation dose and image quality in paediatric chest scans (MDCT), with or without iterative reconstruction (IR). Three anthropomorphic phantoms representing children aged one, five and 10-year-old were explored using AEC system (CARE Dose 4D) with five modulation strength options. For each phantom, six acquisitions were carried out: one with fixed mAs (without AEC) and five each with different modulation strength. Raw data were reconstructed with Filtered Back Projection (FBP) and with two distinct levels of IR using soft and strong kernels. Dose reduction and image quality indices (Noise, SNR, CNR) were measured in lung and soft tissues. Noise Power Spectrum (NPS) was evaluated with a Catphan 600 phantom. The use of AEC produced a significant dose reduction (p<0.01) for all anthropomorphic sizes employed. According to the modulation strength applied, dose delivered was reduced from 43% to 91%. This pattern led to significantly increased noise (p<0.01) and reduced SNR and CNR (p<0.01). However, IR was able to improve these indices. The use of AEC/IR preserved image quality indices with a lower dose delivered. Doses were reduced from 39% to 58% for the one-year-old phantom, from 46% to 63% for the five-year-old phantom, and from 58% to 74% for the 10-year-old phantom. In addition, AEC/IR changed the patterns of NPS curves in amplitude and in spatial frequency. In chest paediatric MDCT, the use of AEC with IR allows one to obtain a significant dose reduction while maintaining constant image quality indices. Copyright © 2016 Associazione Italiana di Fisica Medica. Published by Elsevier Ltd. All rights reserved.

  3. Modeling AEC—New Approaches to Study Rare Genetic Disorders

    Science.gov (United States)

    Koch, Peter J.; Dinella, Jason; Fete, Mary; Siegfried, Elaine C.; Koster, Maranke I.

    2015-01-01

    Ankyloblepharon-ectodermal defects-cleft lip/palate (AEC) syndrome is a rare monogenetic disorder that is characterized by severe abnormalities in ectoderm-derived tissues, such as skin and its appendages. A major cause of morbidity among affected infants is severe and chronic skin erosions. Currently, supportive care is the only available treatment option for AEC patients. Mutations in TP63, a gene that encodes key regulators of epidermal development, are the genetic cause of AEC. However, it is currently not clear how mutations in TP63 lead to the various defects seen in the patients’ skin. In this review, we will discuss current knowledge of the AEC disease mechanism obtained by studying patient tissue and genetically engineered mouse models designed to mimic aspects of the disorder. We will then focus on new approaches to model AEC, including the use of patient cells and stem cell technology to replicate the disease in a human tissue culture model. The latter approach will advance our understanding of the disease and will allow for the development of new in vitro systems to identify drugs for the treatment of skin erosions in AEC patients. Further, the use of stem cell technology, in particular induced pluripotent stem cells (iPSC), will enable researchers to develop new therapeutic approaches to treat the disease using the patient’s own cells (autologous keratinocyte transplantation) after correction of the disease-causing mutations. PMID:24665072

  4. Design of a Low-Power, Small-Area AEC-Q100-Compliant SENT Transmitter in Signal Conditioning IC for Automotive Pressure and Temperature Complex Sensors in 180 Nm CMOS Technology

    Science.gov (United States)

    Rikhan, Behnam Samadpoor; Kim, Dong-Gyu; Lee, Dong-Soo; Rehman, Muhammad Riaz Ur; Abbasizadeh, Hamed; Asif, Muhammad; Lee, Minjae; Yang, Youngoo; Lee, Kang-Yoon

    2018-01-01

    In this paper, a low-power and small-area Single Edge Nibble Transmission (SENT) transmitter design is proposed for automotive pressure and temperature complex sensor applications. To reduce the cost and size of the hardware, the pressure and temperature information is processed with a single integrated circuit (IC) and transmitted at the same time to the electronic control unit (ECU) through SENT. Due to its digital nature, it is immune to noise, has reduced sensitivity to electromagnetic interference (EMI), and generates low EMI. It requires only one PAD for its connectivity with ECU, and thus reduces the pin requirements, simplifies the connectivity, and minimizes the printed circuit board (PCB) complexity. The design is fully synthesizable, and independent of technology. The finite state machine-based approach is employed for area efficient implementation, and to translate the proposed architecture into hardware. The IC is fabricated in 1P6M 180 nm CMOS process with an area of (116 μm × 116 μm) and 4.314 K gates. The current consumption is 50 μA from a 1.8 V supply with a total 90 μW power. For compliance with AEC-Q100 for automotive reliability, a reverse and over voltage protection circuit is also implemented with human body model (HBM) electro-static discharge (ESD) of +6 kV, reverse voltage of −16 V to 0 V, over voltage of 8.2 V to 16 V, and fabricated area of 330 μm × 680 μm. The extensive testing, measurement, and simulation results prove that the design is fully compliant with SAE J2716 standard. PMID:29757996

  5. Impartial Triangular Chocolate Bar Games

    OpenAIRE

    Miyadera, Ryohei; Nakamura, Shunsuke; Fukui, Masanori

    2017-01-01

    Chocolate bar games are variants of the game of Nim in which the goal is to leave your opponent with the single bitter part of the chocolate bar. The rectangular chocolate bar game is a thinly disguised form of classical multi-heap Nim. In this work, we investigate the mathematical structure of triangular chocolate bar games in which the triangular chocolate bar can be cut in three directions. In the triangular chocolate bar game, a position is a $\\mathcal{P}$-position if and only if $x \\oplu...

  6. LH2 three-phase pump control circuit description

    International Nuclear Information System (INIS)

    Pierce, W.

    1977-05-01

    A brief description and circuit drawings are given for a pump control system. The pump is used to circulate liquid hydrogen through the cell and heat exchanger of an LH 2 target. The pump is powered by three-phase 60 cycle power, and the control unit is powered from a positive and negative 24 V dc supply available in the NIM Bin. The control unit is packaged in a double-width NIM module. Drawings are given for the pump speed indicator, function generator, and power supply

  7. Activity of neem tree (Azadirachta indica) leaves aqueous extract on Spodoptera frugiperda

    OpenAIRE

    Prates, Hélio Teixeira; Viana, Paulo Afonso; Waquil, José Magid

    2003-01-01

    A lagarta-do-cartucho do milho (Spodoptera frugiperda (J. E. Smith)) tem sido controlada com inseticidas sintéticos. Uma das caracteristicas do nim (Azadirachta indica A. Juss) é sua atividade inseticida contra pragas, como sucedâneo aos sintéticos. O objetivo deste trabalho foi avaliar a atividade inseticida do extrato aquoso das folhas do nim sobre a lagarta-do-cartucho do milho, em laboratório. Bioensaios com diferentes concentrações de extrato em dieta artificial, tendo o inseticida chlor...

  8. Unrestricted Mintek publications 1966 to 1984

    International Nuclear Information System (INIS)

    Glen, H.W.

    1984-01-01

    This publication lists the 895 unrestricted reports, 508 papers, 45 patents, 5 special publications, and 2 technical bulletins that were issued as publications of the National Institute for Metallurgy (NIM) and the Council for Mineral Technology (Mintek) from 1966 (the year of NIM's inception) to 31st March 1984. For ease of reference, these publications are also classified under research topics. Also included are details of the periodicals issued by Mintek and a list of its current miscellaneous publications, which include brochures and leaflets of various kinds

  9. Commercial Nuclear Steam-Electric Power Plants, Part II

    Science.gov (United States)

    Shore, Ferdinand J.

    1974-01-01

    Presents the pros and cons of nuclear power systems. Includes a discussion of the institutional status of the AEC, AEC regulatory record, routine low-level radiation hazards, transport of radioactive materials, storage of wastes, and uranium resources and economics of supply. (GS)

  10. SMES COMPETITIVENESS IN AN INTEGRATED ECONOMY: A PRELIMINARY STUDY FROM INDONESIA

    Directory of Open Access Journals (Sweden)

    Eko Suseno Hr Matrutty

    2018-03-01

    Full Text Available ASEAN Economic Community (AEC offers both opportunities and challenges to Indonesian Small Medium Enterprises (SMEs. Highly competitive SMEs are likely to exploit opportunities from AEC by expanding their markets and securing raw materials at lower costs. On the contrary, the increasingly intense competition is likely to marginalize less competitive SMEs in their own domestic market. This study aims to analyze the SMEs competitiveness in anticipating AEC. Using 64 SMEs that already export their products or have potentials to export as the sample; this research shows that Indonesian SMEs exhibit a high competitiveness level from the perspective of the production factor, the availability of related and supporting industries factor (especially in relation to the availability of raw and supporting materials, and the demand factor. However, SME owners acknowledge that AEC intensify competition and the government has not provided adequate facilities to improve the SME competitiveness.

  11. Performance of automatic exposure control of digital imaging systems in three big hospitals

    International Nuclear Information System (INIS)

    Avramova-Cholakova, S.; Dyakov, I.

    2012-01-01

    The digital imaging systems are quite new in Bulgaria and there is still no clear evidence between all the servicing companies how to set the automatic exposure control (AEC) of the systems. The aim of this work is to study the AEC settings of the digital imaging systems in three big hospitals, serviced by different engineering companies. This study included seven systems, one with digital radiography (DR) and the others with computed radiography (CR) detectors. The AEC settings were tested in terms of mean pixel value (MPV), air kerma at phantom exit and detector dose indicator (DDI) dependence from AEC chamber selection, tube voltage and phantom thickness. Relatively small variations in MPV up to 8 % were observed for 4 of the CR systems, usually with small variations in DDI as well (except for one system, for which up to 40 % difference in DDI consistency between chambers was found). Air kerma at phantom exit for these systems had bigger variations up to 29 %. The other CR systems had big variations in MPV up to 57 % with DDI variations up to 30 % while air kerma changes were not small - from 8 to 38 %. The DR system showed smaller variation in air kerma at phantom exit up to 8 % and bigger variations in MPV and DDI up to 20 % and 15 % respectively. There is no systematic approach in the AEC settings used in the 3 hospitals. Further investigation and collaboration with the servicing companies is needed aiming to establish the optimized selection of AEC calibration parameters in each case. (authors)

  12. Computed tomography automatic exposure control techniques in 18F-FDG oncology PET-CT scanning.

    Science.gov (United States)

    Iball, Gareth R; Tout, Deborah

    2014-04-01

    Computed tomography (CT) automatic exposure control (AEC) systems are now used in all modern PET-CT scanners. A collaborative study was undertaken to compare AEC techniques of the three major PET-CT manufacturers for fluorine-18 fluorodeoxyglucose half-body oncology imaging. An audit of 70 patients was performed for half-body CT scans taken on a GE Discovery 690, Philips Gemini TF and Siemens Biograph mCT (all 64-slice CT). Patient demographic and dose information was recorded and image noise was calculated as the SD of Hounsfield units in the liver. A direct comparison of the AEC systems was made by scanning a Rando phantom on all three systems for a range of AEC settings. The variation in dose and image quality with patient weight was significantly different for all three systems, with the GE system showing the largest variation in dose with weight and Philips the least. Image noise varied with patient weight in Philips and Siemens systems but was constant for all weights in GE. The z-axis mA profiles from the Rando phantom demonstrate that these differences are caused by the nature of the tube current modulation techniques applied. The mA profiles varied considerably according to the AEC settings used. CT AEC techniques from the three manufacturers yield significantly different tube current modulation patterns and hence deliver different doses and levels of image quality across a range of patient weights. Users should be aware of how their system works and of steps that could be taken to optimize imaging protocols.

  13. Tailoring automatic exposure control toward constant detectability in digital mammography

    Energy Technology Data Exchange (ETDEWEB)

    Salvagnini, Elena, E-mail: elena.salvagnini@uzleuven.be [Department of Imaging and Pathology, Medical Physics and Quality Assessment, KUL, Herestraat 49, Leuven B-3000, Belgium and SCK-CEN, Boeretang 200, Mol 2400 (Belgium); Bosmans, Hilde [Department of Imaging and Pathology, Medical Physics and Quality Assessment, KUL, Herestraat 49, Leuven B-3000, Belgium and Department of Radiology, UZ Gasthuisberg, Herestraat 49, Leuven B-3000 (Belgium); Struelens, Lara [SCK-CEN, Boeretang 200, Mol 2400 (Belgium); Marshall, Nicholas W. [Department of Radiology, UZ Gasthuisberg, Herestraat 49, Leuven B-3000 (Belgium)

    2015-07-15

    Purpose: The automatic exposure control (AEC) modes of most full field digital mammography (FFDM) systems are set up to hold pixel value (PV) constant as breast thickness changes. This paper proposes an alternative AEC mode, set up to maintain some minimum detectability level, with the ultimate goal of improving object detectability at larger breast thicknesses. Methods: The default “OPDOSE” AEC mode of a Siemens MAMMOMAT Inspiration FFDM system was assessed using poly(methyl methacrylate) (PMMA) of thickness 20, 30, 40, 50, 60, and 70 mm to find the tube voltage and anode/filter combination programmed for each thickness; these beam quality settings were used for the modified AEC mode. Detectability index (d′), in terms of a non-prewhitened model observer with eye filter, was then calculated as a function of tube current-time product (mAs) for each thickness. A modified AEC could then be designed in which detectability never fell below some minimum setting for any thickness in the operating range. In this study, the value was chosen such that the system met the achievable threshold gold thickness (T{sub t}) in the European guidelines for the 0.1 mm diameter disc (i.e., T{sub t} ≤ 1.10 μm gold). The default and modified AEC modes were compared in terms of contrast-detail performance (T{sub t}), calculated detectability (d′), signal-difference-to-noise ratio (SDNR), and mean glandular dose (MGD). The influence of a structured background on object detectability for both AEC modes was examined using a CIRS BR3D phantom. Computer-based CDMAM reading was used for the homogeneous case, while the images with the BR3D background were scored by human observers. Results: The default OPDOSE AEC mode maintained PV constant as PMMA thickness increased, leading to a reduction in SDNR for the homogeneous background 39% and d′ 37% in going from 20 to 70 mm; introduction of the structured BR3D plate changed these figures to 22% (SDNR) and 6% (d′), respectively

  14. Tailoring automatic exposure control toward constant detectability in digital mammography.

    Science.gov (United States)

    Salvagnini, Elena; Bosmans, Hilde; Struelens, Lara; Marshall, Nicholas W

    2015-07-01

    The automatic exposure control (AEC) modes of most full field digital mammography (FFDM) systems are set up to hold pixel value (PV) constant as breast thickness changes. This paper proposes an alternative AEC mode, set up to maintain some minimum detectability level, with the ultimate goal of improving object detectability at larger breast thicknesses. The default "opdose" AEC mode of a Siemens MAMMOMAT Inspiration FFDM system was assessed using poly(methyl methacrylate) (PMMA) of thickness 20, 30, 40, 50, 60, and 70 mm to find the tube voltage and anode/filter combination programmed for each thickness; these beam quality settings were used for the modified AEC mode. Detectability index (d'), in terms of a non-prewhitened model observer with eye filter, was then calculated as a function of tube current-time product (mAs) for each thickness. A modified AEC could then be designed in which detectability never fell below some minimum setting for any thickness in the operating range. In this study, the value was chosen such that the system met the achievable threshold gold thickness (Tt) in the European guidelines for the 0.1 mm diameter disc (i.e., Tt ≤ 1.10 μm gold). The default and modified AEC modes were compared in terms of contrast-detail performance (Tt), calculated detectability (d'), signal-difference-to-noise ratio (SDNR), and mean glandular dose (MGD). The influence of a structured background on object detectability for both AEC modes was examined using a CIRS BR3D phantom. Computer-based CDMAM reading was used for the homogeneous case, while the images with the BR3D background were scored by human observers. The default opdose AEC mode maintained PV constant as PMMA thickness increased, leading to a reduction in SDNR for the homogeneous background 39% and d' 37% in going from 20 to 70 mm; introduction of the structured BR3D plate changed these figures to 22% (SDNR) and 6% (d'), respectively. Threshold gold thickness (0.1 mm diameter disc) for the default

  15. AEC Scorecard Phase IV: Furthering the Implementation of the AEC Blueprint Measures The Singapore Country Report

    OpenAIRE

    Hank LIM; Bernard AW; LOKE Hoe Yeong

    2015-01-01

    Singapore is an open economy that is critically dependent on leveraging external resources to achieve its economic growth. To achieve that objective, the government is strongly committed to maintaining a free and competitive economy. In the case of service liberalisation, however, there are a number of restrictions on foreign labour in the service sectors under review that may have an adverse impact on the service sectors. Nonetheless, Singapore is ready to integrate fully into the Associatio...

  16. Overview, practical tips and potential pitfalls of using automatic exposure control in CT: Siemens care dose 4D

    International Nuclear Information System (INIS)

    Soederberg, Marcus

    2016-01-01

    Today, computed tomography (CT) systems routinely use automatic exposure control (AEC), which modulates the tube current. However, for optimal use, there are several aspects of an AEC system that need to be considered. The purpose of this study was to provide an overview of the Siemens CARE Dose 4D AEC system, discuss practical tips and demonstrate potential pitfalls. Two adult anthropomorphic phantoms were examined using two different Siemens CT systems. When optimising the CT radiation dose and image quality, the projection angle of the localiser, patient centring, protocol selection, scanning direction and the use of protective devices requires special attention. (authors)

  17. The Role of Mitochondrial DNA in Mediating Alveolar Epithelial Cell Apoptosis and Pulmonary Fibrosis

    Science.gov (United States)

    Kim, Seok-Jo; Cheresh, Paul; Jablonski, Renea P.; Williams, David B.; Kamp, David W.

    2015-01-01

    Convincing evidence has emerged demonstrating that impairment of mitochondrial function is critically important in regulating alveolar epithelial cell (AEC) programmed cell death (apoptosis) that may contribute to aging-related lung diseases, such as idiopathic pulmonary fibrosis (IPF) and asbestosis (pulmonary fibrosis following asbestos exposure). The mammalian mitochondrial DNA (mtDNA) encodes for 13 proteins, including several essential for oxidative phosphorylation. We review the evidence implicating that oxidative stress-induced mtDNA damage promotes AEC apoptosis and pulmonary fibrosis. We focus on the emerging role for AEC mtDNA damage repair by 8-oxoguanine DNA glycosylase (OGG1) and mitochondrial aconitase (ACO-2) in maintaining mtDNA integrity which is important in preventing AEC apoptosis and asbestos-induced pulmonary fibrosis in a murine model. We then review recent studies linking the sirtuin (SIRT) family members, especially SIRT3, to mitochondrial integrity and mtDNA damage repair and aging. We present a conceptual model of how SIRTs modulate reactive oxygen species (ROS)-driven mitochondrial metabolism that may be important for their tumor suppressor function. The emerging insights into the pathobiology underlying AEC mtDNA damage and apoptosis is suggesting novel therapeutic targets that may prove useful for the management of age-related diseases, including pulmonary fibrosis and lung cancer. PMID:26370974

  18. Evaluation of the individual tube current setting in electrocardiogram-gated cardiac computed tomography estimated from plain chest computed tomography using computed tomography automatic exposure control

    International Nuclear Information System (INIS)

    Kishimoto, Junichi; Sakou, Toshio; Ohta, Yasutoshi

    2013-01-01

    The aim of this study was to estimate the tube current on a cardiac computed tomography (CT) from a plain chest CT using CT-automatic exposure control (CT-AEC), to obtain consistent image noise, and to optimize the scan tube current by individualizing the tube current. Sixty-five patients (Group A) underwent cardiac CT at fixed tube current. The mAs value for plain chest CT using CT-AEC (AEC value) and cardiac CT image noise were measured. The tube current needed to obtain the intended level of image noise in the cardiac CT was determined from their correlation. Another 65 patients (Group B) underwent cardiac CT with tube currents individually determined from the AEC value. Image noise was compared among Group A and B. Image noise of cardiac CT in Group B was 24.4±3.1 Hounsfield unit (HU) and was more uniform than in Group A (21.2±6.1 HU). The error with the desired image noise of 25 HU was lower in Group B (2.4%) than in Group A (15.2%). Individualized tube current selection based on AEC value thus provided consistent image noise and a scan tube current optimized for cardiac CT. (author)

  19. "Русские!" Русские?.. И Казимир Малевич / Этэри Кекелидзе

    Index Scriptorium Estoniae

    Кекелидзе, Этэри, 1944-

    2014-01-01

    Ülevaade XXIII Peterburi teatrifestivalist "Balti kodu" 2013. a. Pikemalt Ivo van Hove lavastusest Tšehhovi näidendite järgi "De Russen!" (Toneelgroep Amsterdam (Holland)), Alvis Hermanise lavastusest "Oblomov" (Riia Uus Teater), Luk Percevali lavastusest "Vennad Karamazovid" (Theater Thalia (Saksamaa)), Bram Janseni lavastusest Strindbergi "Preili Julie" järgi "Kijken naar Julie" (Bram Jansen Company (Holland)), Juri Butussovi lavastusest "Macbeth-Kino" (Peterburi Lensoveti-nim. Teater), Grigori Kozlovi lavastusest "Vaikne Don" (Мастерская (Peterburi)) ning Rimas Tuminase lavastusest "Jevgeni Onegin" (Vahtangovi-nim. Teater (Moskva))

  20. The G2/M DNA damage checkpoint inhibits mitosis through Tyr15 phosphorylation of p34cdc2 in Aspergillus nidulans.

    Science.gov (United States)

    Ye, X S; Fincher, R R; Tang, A; Osmani, S A

    1997-01-02

    It is possible to cause G2 arrest in Aspergillus nidulans by inactivating either p34cdc2 or NIMA. We therefore investigated the negative control of these two mitosis-promoting kinases after DNA damage. DNA damage caused rapid Tyr15 phosphorylation of p34cdc2 and transient cell cycle arrest but had little effect on the activity of NIMA. Dividing cells deficient in Tyr15 phosphorylation of p34cdc2 were sensitive to both MMS and UV irradiation and entered lethal premature mitosis with damaged DNA. However, non-dividing quiescent conidiospores of the Tyr15 mutant strain were not sensitive to DNA damage. The UV and MMS sensitivity of cells unable to tyrosine phosphorylate p34cdc2 is therefore caused by defects in DNA damage checkpoint regulation over mitosis. Both the nimA5 and nimT23 temperature-sensitive mutations cause an arrest in G2 at 42 degrees C. Addition of MMS to nimT23 G2-arrested cells caused a marked delay in their entry into mitosis upon downshift to 32 degrees C and this delay was correlated with a long delay in the dephosphorylation and activation of p34cdc2. Addition of MMS to nimA5 G2-arrested cells caused inactivation of the H1 kinase activity of p34cdc2 due to an increase in its Tyr15 phosphorylation level and delayed entry into mitosis upon return to 32 degrees C. However, if Tyr15 phosphorylation of p34cdc2 was prevented then its H1 kinase activity was not inactivated upon MMS addition to nimA5 G2-arrested cells and they rapidly progressed into a lethal mitosis upon release to 32 degrees C. Thus, Tyr15 phosphorylation of p34cdc2 in G2 arrests initiation of mitosis after DNA damage in A. nidulans.

  1. Regulation of nuclear power: the case of the light water reactor

    International Nuclear Information System (INIS)

    Rolph, E.

    1977-06-01

    This report is one of a series of documents that trace the history of the development and commercialization of the light water reactor in the expectation that a better appreciation of the development and commercialization process of this complex technology could be instructive in understanding the regulatory and economic obstacles currently slowing diffusion of that technology and the problems that may be encountered in similar large-scale, high-technology development projects. This regulatory history of the Atomic Energy Commission chronicles the significant events between 1954, when the AEC was given responsibility for regulating nuclear power plants, and 1974, when the AEC was absorbed by the Energy Research and Development Administration and the Nuclear Regulatory Commission. It identifies the origins of regulatory problems that have arisen during the period and describes how the AEC dealt with them. The history is based, for the most part, on primary source documents: hearings, news reports, and AEC documents

  2. Noncondensable hydrogen sulfide incineration with brine scrubbing air emissions control system

    International Nuclear Information System (INIS)

    Goddard, W.B.; Goddard, C.B.; McClain, D.W.

    1990-01-01

    This paper reports on the technical and institutional feasibility of incinerating hydrogen sulfide (H2S) contained in geothermal noncondensable gases, and the use of geothermal brine for sulfur dioxide scrubbing and absorption as an Air Emissions Control System (AECS), for geothermal power plant, that have been documented through engineering analysis in the Phase I grant study funded through the California Department of Health Services (DOHS), Hazardous Materials Reduction Grant Program and hosted by California Energy Company (CECI). Grant funding for Phase II now has been approved to proceed with the project through the pilot plant design phase. This innovative AECS does not necessitate the use of hazardous materials or produce hazardous wastes. Cost savings were documented compared to injection pump operation or conventional AECS without the use of hazardous materials. The phase II project is to design, improve, research and develop a source reduction demonstration pilot plant geothermal noncondensable H2S incineration AECS

  3. Expression and prognostic value of putative cancer stem cell markers CD117 and CD15 in choroidal and ciliary body melanoma.

    Science.gov (United States)

    Lukenda, Adrian; Dotlic, Snjezana; Vukojevic, Nenad; Saric, Borna; Vranic, Semir; Zarkovic, Kamelija

    2016-03-01

    The aim of the present study was to immunohistochemically investigate the expression and prognostic significance of putative cancer stem cell markers CD117 (c-kit), CD34, CD20 and CD15 in a cohort of patients with primary choroidal and ciliary body melanoma. The immunohistochemical expression of these markers was evaluated using 3,3'-diaminobenzidine tetrahydrochloride (DAB) and 3-amino-9-ethylcarbazole (AEC) chromogens on paraffin-embedded tissue samples from 40 patients who underwent enucleation in the period from 1985 through 2000. Thirty-one patients had adequate tissue specimens for the analysis. CD117 overexpression was observed in 12 of the 31 samples (39%) when AEC chromogen was used and in 14 of 26 (54%) samples when DAB was used. CD15 positivity was seen in three out of 30 (10%) samples with AEC and in six out of 26 (23%) samples with DAB. CD20 and CD34 exhibited no positivity in the tested samples. During the average follow-up time of 8.7 years (range 0.5-22 years), 17 patients (55%) died due to metastatic disease. The Kaplan-Meier plots showed a significantly shorter overall and disease-free survival in CD117-positive patients when the AEC chromogen was used. CD15 expression was not associated with patients' survival. In multivariate analysis, patients expressing the CD117 AEC had 4.13 times higher risk of lethal outcome in comparison with CD117 AEC negative patients. Our retrospective cohort study has for the first time demonstrated a small proportion of CD15-positive uveal melanomas. CD117 AEC overexpression was associated with a worse outcome in patients with choroidal and ciliary body melanoma. Further studies should confirm the validity of these observations and their potential for targeted treatment modalities. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/

  4. Mesenchymal Stem Cell Conditioned Medium Promotes Proliferation and Migration of Alveolar Epithelial Cells under Septic Conditions In Vitro via the JNK-P38 Signaling Pathway

    Directory of Open Access Journals (Sweden)

    Jie Chen

    2015-11-01

    Full Text Available Background/Aims: Mesenchymal stem cell (MSC based therapies may be useful for treating acute respiratory distress syndrome (ARDS, but the underlying mechanisms are incompletely understood. We investigated the impact of human umbilical cord Wharton's jelly-derived MSC (hUC-MSC secreted factors on alveolar epithelial cells under septic conditions and determined the relevant intracellular signaling pathways. Methods: Human alveolar epithelial cells (AEC and primary human small airway epithelial cells (SAEC were subjected to lipopolysaccharide (LPS with or without the presence of hUC-MSC-conditioned medium (CM. Proliferation and migration of AEC and SAEC were determined via an MTT assay, a wound healing assay and a transwell migration assay (only for AEC. Protein phosphorylation was determined by western blot and the experiments were repeated in presence of small-molecule inhibitors. The hMSC-secretory proteins were identified by LC-MS/MS mass spectrometry. Results: MSC-CM enhanced proliferation and migration. Activation of JNK and P38, but not ERK, was required for the proliferation and migration of AEC and SAEC. Pretreatment of AEC or SAEC with SP600125, an inhibitor of JNK1 or SB200358, an inhibitor of P38, significantly reduced cell proliferation and migration. An array of proteins including TGF-beta receptor type-1, TGF-beta receptor type-2, Ras-related C3 botulinum toxin substrate 1 and Ras-related C3 botulinum toxin substrate 2 which influencing the proliferation and migration of AEC and SAEC were detected in MSC-CM. Conclusion: Our data suggest MSC promote epithelial cell repair through releasing a repertoire of paracrine factors via activation of JNK and P38 MAPK.

  5. Literary awards 2003 / Piret Viires

    Index Scriptorium Estoniae

    Viires, Piret, 1963-

    2004-01-01

    Riigi kultuuripreemia - Vello Salo (elutööpreemia) ; Eesti Kultuurkapitali aastapreemia - Toomas Liiv ("Luuletused 1968-2002") ; Kultuurkapitali kirjanduse aastapreemiad: proosa - Nikolai Baturin ("Kentaur"), luule - Asko Künnap ("Ja sisalikud vastasid (kolmes kirjas)"), esseistika - Toomas Raudam ("Teie"), näitekirjandus - Mati Unt ("Vend Antigone, ema Oidipus", "Stiil, ehk, Mis on maailma nimi", "Kärbeste saar"), lastekirjandus - Katrin Reimus ("Haldjatants"), tõlge eesti keelde - Jaak Rähesoo (J. Joyce'i "Kunstniku noorpõlve portree" ja "Pagulaste" tõlked), tõlge eesti keelest - Eric Dickens (J. Krossi "Paigallennu" tõlge), artiklipreemia - Arne Merilai (järelsõna antoloogiale "Eesti ballaad"), venekeelsete autorite kirjandusauhind - Marina Tervonen (luulekogu "Ületamine") ; B. Alveri kirjandusauhind - Erkki Luuk ("Ornitoloogi pealehakkamine") ; F. Tuglase novelliauhind - Lauri Pilter ("Teisik"), Ilmar Jaks (novell "Armer Adolf" ja novellikogu "Pimedus") ; A. H. Tammsaare nim. kirjanduspreemia - Rein Veidemann ("Lastekodu") ; E. Vilde nim. kirjandusauhind - Eeva Park ("Lõks lõpmatuses") ; Nukitsa auhind - Janno Põldma ja Heiki Ernits ("Lepatriinude jõulud") ; K. E. Söödi nim. lasteluulepreemia - Jaanus Vaiksoo (luulekogu "Kellassepaproua") ; Eesti Raudtee ja Sirbi kirjandusauhind - Andres Vanapa ("Päti vile") ja Kristiina Ehin ("Simunapäev")

  6. Near-Infrared Mapping Spectrometer for investigation of Jupiter and its satellites

    International Nuclear Information System (INIS)

    Aptaker, I.M.

    1988-01-01

    The Near-Infrared-Mapping Spectrometer (NIMS) is one of the science instruments in the Galileo mission, which will explore Jupiter and its satellites in the mid-1990's. The NIMS experiment will map geological units on the surfaces of the Jovian satellites and characterize their mineral content; and, for the atmosphere of Jupiter, investigate cloud properties and the spatial and temporal variability of molecular abundances. The optics are gold-coated reflective and consist of a telescope and a grating spectrometer. The balance of the instrument includes a 17-detector (silicon and indium antimonide) focal plane array, a tuning fork chopper, microprocessor-controlled electronics, and a passive radiative cooler. A wobbling secondary mirror in the telescope provides 20 pixels in one dimension of spatial scanning in a pushbroom mode with 0.5 mr x 0.5 mr instantaneous field of view. The spectral range is 0.7-5.2 microns; resolution is 0.025 micron. NIMS is the first infrared experiment to combine both spatial and spectral mapping capability in one instrument

  7. Ação de Inseticidas Botânicos sobre a Preferência Alimentar e sobre Posturas de Spodoptera frugiperda (J.E. Smith (Lepidoptera: Noctuidae em Milho

    Directory of Open Access Journals (Sweden)

    Fábio Mazzonetto

    2013-04-01

    Full Text Available O presente trabalho objetivou comparar o efeito de diferentes extratos de origem vegetal na preferência alimentar e na postura da lagarta do cartucho Spodoptera frugiperda (J.E. Smith em folhas de milho. Extratos aquosos a 10% p/v de Chenopodium ambrosioides (Linnaeus (Erva de Santa Maria, Corymbia citriodora (Hill & Johnson (Eucalipto Cheiroso, Chrysanthemum leucanthemum (Linnaeus (Crisântemo e Azadirachta indica (A. Juss (Nim foram aplicados em discos de folhas de milho e oferecidos às lagartas em testes com e sem chance de escolha. A atratividade das lagartas pelos discos com os extratos não diferiu da testemunha no teste com chance de escolha, porém os extratos de Nim e Crisântemo apresentaram efeito fagodeterrente a S. frugiperda. Nos testes sem chance de escolha, o tratamento que mais repeliu as lagartas foi utilizando extrato de Nim, representando possível alternativa para o controle das lagartas desta espécie. Nenhum dos extratos aquosos das espécies vegetais testadas apresentou efeito ovicida.

  8. Late pest control in determinate tomato cultivars Controle de pragas tardias em cultivares de tomateiro de crescimento determinado

    Directory of Open Access Journals (Sweden)

    Arlindo Leal Boiça Júnior

    2007-12-01

    Full Text Available The usage of insecticidal plants and others insect resistant varieties can be strong allies to the Integrated Pest Management (IPM, being able to reduce the number of insecticides applications and to minimize its effect to the man and the environment.The following control techniques were compared in field conditions, investigating the late pest control of two determinate tomato cultivars: a Conventional - sprayings of metamidophos, buprofezin, acephate, cipermetrin, abamectin, permetrin, teflubenzuron and lufenuron, applied every three to six days; b IPM - action threshold of each pest to the spraying of imidacloprid, triflumuron, lufenuron and abamectin; c IPM - Azadirachta indica (neem - Action threshold of each pest to the spraying of the nim oil (1.2% of azadirachtin at a concentration of 0.5%. The IPM and IPM - Neem control techniques were efficient controlling the late pest of the tomato cultivar, not differing from the conventional treatment that presented the lowest levels of infestation. The conventional control technique, IPM and IPM-neem promoted bigger tomato production with increasements of up to 74%. The number of sprayings was reduced up to 77% with the IPM and IPM - neem techniques, when compared to the conventional method. The neem product may be a promising alternative to the late pest control in the tomato field that adjusts to the IPM.O uso de plantas inseticidas e de variedades pode ser forte aliado ao Manejo Integrado de Pragas (MIP, podendo reduzir o número de aplicações de inseticidas e minimizar seus efeitos ao homem e ao meio ambiente. Em condições de campo, visando o controle de pragas tardias do tomateiro em duas cultivares de crescimento determinado, compararam-se as seguintes táticas de controle: a Convencional - pulverizações com os produtos metamidofós, buprofezin, acefato, cipermetrina, abamectina, permetrina, teflubenzuron e lufenuron, aplicados em intervalos de três a seis dias; b MIP - nível de a

  9. Human-like Compliance for Dexterous Robot Hands

    Science.gov (United States)

    Jau, Bruno M.

    1995-01-01

    This paper describes the Active Electromechanical Compliance (AEC) system that was developed for the Jau-JPL anthropomorphic robot. The AEC system imitates the functionality of the human muscle's secondary function, which is to control the joint's stiffness: AEC is implemented through servo controlling the joint drive train's stiffness. The control strategy, controlling compliant joints in teleoperation, is described. It enables automatic hybrid position and force control through utilizing sensory feedback from joint and compliance sensors. This compliant control strategy is adaptable for autonomous robot control as well. Active compliance enables dual arm manipulations, human-like soft grasping by the robot hand, and opens the way to many new robotics applications.

  10. Efficient multichannel acoustic echo cancellation using constrained tap selection schemes in the subband domain

    Science.gov (United States)

    Desiraju, Naveen Kumar; Doclo, Simon; Wolff, Tobias

    2017-12-01

    Acoustic echo cancellation (AEC) is a key speech enhancement technology in speech communication and voice-enabled devices. AEC systems employ adaptive filters to estimate the acoustic echo paths between the loudspeakers and the microphone(s). In applications involving surround sound, the computational complexity of an AEC system may become demanding due to the multiple loudspeaker channels and the necessity of using long filters in reverberant environments. In order to reduce the computational complexity, the approach of partially updating the AEC filters is considered in this paper. In particular, we investigate tap selection schemes which exploit the sparsity present in the loudspeaker channels for partially updating subband AEC filters. The potential for exploiting signal sparsity across three dimensions, namely time, frequency, and channels, is analyzed. A thorough analysis of different state-of-the-art tap selection schemes is performed and insights about their limitations are gained. A novel tap selection scheme is proposed which overcomes these limitations by exploiting signal sparsity while not ignoring any filters for update in the different subbands and channels. Extensive simulation results using both artificial as well as real-world multichannel signals show that the proposed tap selection scheme outperforms state-of-the-art tap selection schemes in terms of echo cancellation performance. In addition, it yields almost identical echo cancellation performance as compared to updating all filter taps at a significantly reduced computational cost.

  11. An aqueous extract of Curcuma longa (turmeric) rhizomes stimulates insulin release and mimics insulin action on tissues involved in glucose homeostasis in vitro.

    Science.gov (United States)

    Mohankumar, Sureshkumar; McFarlane, James R

    2011-03-01

    Curcuma longa (turmeric) has been used widely as a spice, particularly in Asian countries. It is also used in the Ayurvedic system of medicine as an antiinflammatory and antimicrobial agent and for numerous other curative properties. The aim of this study was to investigate the effects of an aqueous extract of Curcuma longa (AEC) on tissues involved in glucose homeostasis. The extract was prepared by soaking 100 g of ground turmeric in 1 L of water, which was filtered and stored at -20°C prior to use. Pancreas and muscle tissues of adult mice were cultured in DMEM with 5 or 12 mmol/L glucose and varying doses of extract. The AEC stimulated insulin secretion from mouse pancreatic tissues under both basal and hyperglycaemic conditions, although the maximum effect was only 68% of that of tolbutamide. The AEC induced stepwise stimulation of glucose uptake from abdominal muscle tissues in the presence and absence of insulin, and the combination of AEC and insulin significantly potentiated the glucose uptake into abdominal muscle tissue. However, this effect was attenuated by wortmannin, suggesting that AEC possibly acts via the insulin-mediated glucose uptake pathway. In summary, water soluble compounds of turmeric exhibit insulin releasing and mimicking actions within in vitro tissue culture conditions. Copyright © 2010 John Wiley & Sons, Ltd.

  12. Effective Regulatory Control of Radioactive Sources in Taiwan

    International Nuclear Information System (INIS)

    Liu, W.; Yuan, C.; Fan, S.; Su, S.

    2004-01-01

    Since the incident of radioactively contaminated buildings first surfaced in Taiwan in 1992, efforts have been made by AEC (Atomic Energy Council) of Taiwan to prevent recurrence of similar incidents involving radioactive materials and to achieve effective regulatory control over radioactive sources. The most important milestone is when AEC began to enforce IRPA he Ionizing Radiation Protection Act with the promulgation of 18 relevant regulations on Feb. 1, 2003. In order to enhance accountability of radioactive material and equipment capable of producing ionizing radiation, AEC develops and begins implementing a RPCS Radiation Protection Control System which is a powerful tool in controlling radiation safety and security. In addition, AEC develops a monthly registration program via internet, an o n-line reporting system f or owners/operators of radioactive sources, to improve monitoring of sealed sources (in-use and not-in-use). The registration requirement applies to 469 licensees possessing about 3,000 sealed sources in Taiwan. Because of the threat of orphan sources, AEC has made great efforts in preventing their contamination of construction steel material by establishing and enforcing the RPMMPIRCB Regulation for Preventive Measures and Management Plans for Incident of Radioactively Contaminated Buildings. To comply with this regulation, all 19 of Taiwan's steel factories with melting furnace have installed portal-type radiation detection system to monitor incoming scrap metal. (Author)

  13. In vivo click reaction between Tc-99m-labeled azadibenzocyclooctyne-MAMA and 2-nitroimidazole-azide for tumor hypoxia targeting.

    Science.gov (United States)

    Sun, Wenjing; Chu, Taiwei

    2015-10-15

    The bioactivity of nitroimidazole in Tc-99m-labeled 2-nitroimidazole, a traditional solid tumor hypoxia-imaging agent for single photon emission computed tomography (SPECT), is reduced by the presence of large ligand and metallic radionuclide, exhibiting lower tumor-to-nontumor ratios. In an effort to solve this general problem, a pretargeting strategy based on click chemistry (strain-promoted cyclooctyne-azide cycloaddition) was applied. The functional click synthons were synthesized as pretargeting components: an azide group linked to 2-nitroimidazole (2NIM-Az) serves for tumor hypoxia-targeting and azadibenzocyclooctyne conjugated with monoamine monoamide dithiol ligand (AM) functions as radiolabeling and binding group to azides in vivo. 2NIM-triazole-MAMA was obtained from in vitro click reaction with a reaction rate constant of 0.98M(-1)s(-1). AM and 2NIM-triazole-MAMA were radiolabeled with Tc-99m. The hypoxia-pretargeting biodistribution was studied in Kunming mice bearing S180 tumor; (99m)Tc-AM and (99m)Tc-triazole-2NIM were used as blank control and conventional control. Compared to the control groups, the pretargeting experiment exhibits the best radio-uptake and retention in tumor, with higher tumor-to-muscle and tumor-to-blood ratios (up to 8.55 and 1.44 at 8h post-(99m)Tc-complex-injection, respectively). To some extent, the pretargeting strategy protects the bioactivity of nitroimidazole and therefore provides an innovative approach for the development of tumor hypoxia-SPECT imaging agents. Copyright © 2015 Elsevier Ltd. All rights reserved.

  14. 24-channel dual microcontroller-based voltage controller for ion optics remote control

    Science.gov (United States)

    Bengtsson, L.

    2018-05-01

    The design of a 24-channel voltage control instrument for Wenzel Elektronik N1130 NIM modules is described. This instrument is remote controlled from a LabVIEW GUI on a host Windows computer and is intended for ion optics control in electron affinity measurements on negative ions at the CERN-ISOLDE facility. Each channel has a resolution of 12 bits and has a normally distributed noise with a standard deviation of <1 mV. The instrument is designed as a standard 2-unit NIM module where the electronic hardware consists of a printed circuit board with two asynchronously operating microcontrollers.

  15. Improved covariance matrix estimation in spectrally inhomogeneous sea clutter with application to adaptive small boat detection.

    CSIR Research Space (South Africa)

    Herselman, PL

    2008-09-01

    Full Text Available and that is necessary to set the threshold χt as a function of the steering vector Doppler fd. Improvements to the estimation technique are suggested and evaluated where a more localised M is estimated using either frequency agility or the immediate time history... of frequency, calculated as NIM2(fd) = E{z(fd)2}/E2{z(fd)} , (3) where z(fd) is the power spectral density at fd. This is often used to quantify the Rayleigh-likeness of the envelope 0 5 10 15 −500 −250 0 250 500 Doppler frequency [Hz ] NIM2Time [s...

  16. Non-antibiotic selection systems for soybean somatic embryos: the lysine analog aminoethyl-cysteine as a selection agent

    Directory of Open Access Journals (Sweden)

    Kwanyuen Prachuab

    2009-11-01

    Full Text Available Abstract Background In soybean somatic embryo transformation, the standard selection agent currently used is hygromycin. It may be preferable to avoid use of antibiotic resistance genes in foods. The objective of these experiments was to develop a selection system for producing transgenic soybean somatic embryos without the use of antibiotics such as hygromycin. Results When tested against different alternate selection agents our studies show that 0.16 μg/mL glufosinate, 40 mg/L isopropylamine-glyphosate, 0.5 mg/mL (S-(2 aminoethyl-L-cysteine (AEC and the acetolactate synthase (ALS inhibitors Exceed® and Synchrony® both at 150 μg/mL inhibited soybean somatic embryo growth. Even at the concentration of 2 mg/mL, lysine+threonine (LT were poor selection agents. The use of AEC may be preferable since it is a natural compound. Unlike the plant enzyme, dihydrodipicolinate synthase (DHPS from E. coli is not feed-back inhibited by physiological concentrations of lysine. The dapA gene which codes for E. coli DHPS was expressed in soybean somatic embryos under the control of the CaMV 35S promoter. Following introduction of the construct into embryogenic tissue of soybean, transgenic events were recovered by incubating the tissue in liquid medium containing AEC at a concentration of 5 mM. Only transgenic soybeans were able to grow at this concentration of AEC; no escapes were observed. Conclusion Genetically engineered soybeans expressing a lysine insensitive DHPS gene can be selected with the non-antibiotic selection agent AEC. We also report here the inhibitory effects of glufosinate, (isopropylamine-glyphosate (Roundup®, AEC and the ALS inhibitors Exceed® and Synchrony® against different tissues of soybean

  17. Evaluation of automatic exposure control systems in computed tomography

    International Nuclear Information System (INIS)

    Reina, Thamiris Rosado

    2014-01-01

    The development of the computed tomography (CT) technology has brought wider possibilities on diagnostic medicine. It is a non-invasive method to see the human body in details. As the CT application increases, it raises the concern about patient dose, because the higher dose levels imparted compared to other diagnostic imaging modalities. The radiology community (radiologists, medical physicists and manufacturer) are working together to find the lowest dose level possible, without compromising the diagnostic image quality. The greatest and relatively new advance to lower the patient dose is the automatic exposure control (AEC) systems in CT. These systems are designed to ponder the dose distribution along the patient scanning and between patients taking into account their sizes and irradiated tissue densities. Based on the CT scanning geometry, the AEC-systems are very complex and their functioning is yet not fully understood. This work aims to evaluate the clinical performance of AEC-systems and their susceptibilities to assist on possible patient dose optimizations. The approach to evaluate the AEC-systems of three of the leading CT manufacturers in Brazil, General Electric, Philips and Toshiba, was the extraction of tube current modulation data from the DICOM standard image sequences, measurement and analysis of the image noise of those image sequences and measurement of the dose distribution along the scan length on the surface and inside of two different phantoms configurations. The tube current modulation of each CT scanner associated to the resulted image quality provides the performance of the AECsystem. The dose distribution measurements provide the dose profile due to the tube current modulation. Dose measurements with the AEC-system ON and OFF were made to quantify the impact of these systems regarding patient dose. The results attained give rise to optimizations on the AEC-systems applications and, by consequence, decreases the patient dose without

  18. Evaluation of automatic exposure control systems in computed tomography

    Energy Technology Data Exchange (ETDEWEB)

    Reina, Thamiris Rosado

    2014-07-01

    The development of the computed tomography (CT) technology has brought wider possibilities on diagnostic medicine. It is a non-invasive method to see the human body in details. As the CT application increases, it raises the concern about patient dose, because the higher dose levels imparted compared to other diagnostic imaging modalities. The radiology community (radiologists, medical physicists and manufacturer) are working together to find the lowest dose level possible, without compromising the diagnostic image quality. The greatest and relatively new advance to lower the patient dose is the automatic exposure control (AEC) systems in CT. These systems are designed to ponder the dose distribution along the patient scanning and between patients taking into account their sizes and irradiated tissue densities. Based on the CT scanning geometry, the AEC-systems are very complex and their functioning is yet not fully understood. This work aims to evaluate the clinical performance of AEC-systems and their susceptibilities to assist on possible patient dose optimizations. The approach to evaluate the AEC-systems of three of the leading CT manufacturers in Brazil, General Electric, Philips and Toshiba, was the extraction of tube current modulation data from the DICOM standard image sequences, measurement and analysis of the image noise of those image sequences and measurement of the dose distribution along the scan length on the surface and inside of two different phantoms configurations. The tube current modulation of each CT scanner associated to the resulted image quality provides the performance of the AECsystem. The dose distribution measurements provide the dose profile due to the tube current modulation. Dose measurements with the AEC-system ON and OFF were made to quantify the impact of these systems regarding patient dose. The results attained give rise to optimizations on the AEC-systems applications and, by consequence, decreases the patient dose without

  19. Human radiation studies: Remembering the early years. Oral history of Merril Eisenbud, January 26, 1995

    International Nuclear Information System (INIS)

    1995-05-01

    Merril Eisenbud was interviewed on January 26, 1995 by representatives of the US DOE Office of Human Radiation Experiments. Following a brief biographical sketch, Mr. Eisenbud relates his remembrances as the AEC's first industrial hygienist, the setting up of AEC's Health and Safety Laboratory, monitoring radioactive fallout, and use or exposure of humans to radiation

  20. Worker radiation doses in the United States at the dawn of the atomic era (1940--1960)

    International Nuclear Information System (INIS)

    Strom, D.J.; Smith, M.H.; Swinth, K.L.; Pettengill, H.J.

    1994-06-01

    Radiation doses to workers at the Manhattan Engineer District (MED) and US Atomic Energy Commission (AEC) sites due to external irradiation during 1940--1960 are reviewed. Categorized radiation dose data were available from AEC annual reports for some years. Annual individual radiation dose data for ten MED/AEC sites for all years were available from the US Department of Energy's (DOE) Comprehensive Epidemiologic Data Resource (CEDR). These data are combined to produce an estimate of external collective dose equivalent to 172,000 person-rems (1720 person-Sv) for 1940--1960. During this period there were 41 overexposures, 19 criticality incidents, and 3 deaths due to acute radiation syndrome among several hundred thousand workers

  1. [Advances in research on automatic exposure control of mammography system].

    Science.gov (United States)

    Wang, Guoyi; Ye, Chengfu; Wu, Haiming; Wang, Tainfu; Zhang, Hong

    2014-12-01

    Mammography imaging is one of the most demanding imaging modalities from the point of view of the bal- ance between image quality (the visibility of small size and/or low contrast structures) and dose (screening of many asymptomatic people). Therefore, since the introduction of the first dedicated mammographic units, many efforts have been directed to seek the best possible image quality while minimizing patient dose. The performance of auto- matic exposure control (AEC) is the manifestation of this demand. The theory of AEC includes exposure detection and optimization and also involves some accomplished methodology. This review presents the development and present situa- tion of spectrum optimization, detector evolution, and the way how to accomplish and evaluate AEC methods.

  2. Human amniotic epithelial cell feeder layers maintain human iPS cell pluripotency via inhibited endogenous microRNA-145 and increased Sox2 expression

    International Nuclear Information System (INIS)

    Liu, Te; Cheng, Weiwei; Huang, Yongyi; Huang, Qin; Jiang, Lizhen; Guo, Lihe

    2012-01-01

    Currently, human induced pluripotent stem (iPS) cells were generated from patient or disease-specific sources and share the same key properties as embryonic stem cells. This makes them attractive for personalized medicine, drug screens or cellular therapy. Long-term cultivation and maintenance of normal iPS cells in an undifferentiated self-renewing state are a major challenge. Our previous studies have shown that human amniotic epithelial cells (HuAECs) could provide a good source of feeder cells for mouse and human embryonic stem cells, or spermatogonial stem cells, but the mechanism for this is unknown. Here, we examined the effect of endogenous microRNA-145 regulation on Sox2 expression in human iPS cells by HuAECs feeder cells regulation, and in turn on human iPS cells pluripotency. We found that human IPS cells transfected with a microRNA-145 mutant expressed Sox2 at high levels, allowing iPS to maintain a high level of AP activity in long-term culture and form teratomas in SCID mice. Expression of stem cell markers was increased in iPS transfected with the microRNA-145 mutant, compared with iPS was transfected with microRNA-145. Besides, the expression of Drosha proteins of the microRNA-processor complex, required for the generation of precursor pre-miRNA, was significantly increased in human iPS cells cultured on MEF but not on HuAECs. Taken together, these results suggest that endogenous Sox2 expression may be regulated by microRNA-145 in human iPS cells with HuAECs feeder cells, and Sox2 is a crucial component required for maintenance of them in an undifferentiated, proliferative state capable of self-renewal. Highlights: ► microRNA-145 inhibits Sox2 expression in human iPS cells. ► microRNA-145 suppresses the self-renewal and pluripotency of human iPS cells. ► HuAECs regulate expression of microRNA-145 and Sox2 in human iPS cells. ► HuAECs feeder layers maintain human iPS cells pluripotency. ► HuAECs negatively regulates the synthesis of

  3. Human amniotic epithelial cell feeder layers maintain human iPS cell pluripotency via inhibited endogenous microRNA-145 and increased Sox2 expression

    Energy Technology Data Exchange (ETDEWEB)

    Liu, Te, E-mail: liute79@yahoo.com [School of Environmental Science and Engineering, Donghua University, Shanghai 201620 (China); Shanghai Geriatric Institute of Chinese Medicine, Shanghai 200031 (China); Cheng, Weiwei [International Peace Maternity and Child Health Hospital, Shanghai Jiaotong University, Shanghai 200030 (China); Huang, Yongyi [Laboratoire PROTEE, Batiment R, Universite du Sud Toulon-Var, 83957 LA GARDE Cedex (France); Huang, Qin; Jiang, Lizhen [Institute of Biochemistry and Cell Biology, Shanghai Institute for Biological Sciences, Chinese Academy of Sciences, Shanghai 200031 (China); Guo, Lihe, E-mail: liute79@yahoo.com [Institute of Biochemistry and Cell Biology, Shanghai Institute for Biological Sciences, Chinese Academy of Sciences, Shanghai 200031 (China)

    2012-02-15

    Currently, human induced pluripotent stem (iPS) cells were generated from patient or disease-specific sources and share the same key properties as embryonic stem cells. This makes them attractive for personalized medicine, drug screens or cellular therapy. Long-term cultivation and maintenance of normal iPS cells in an undifferentiated self-renewing state are a major challenge. Our previous studies have shown that human amniotic epithelial cells (HuAECs) could provide a good source of feeder cells for mouse and human embryonic stem cells, or spermatogonial stem cells, but the mechanism for this is unknown. Here, we examined the effect of endogenous microRNA-145 regulation on Sox2 expression in human iPS cells by HuAECs feeder cells regulation, and in turn on human iPS cells pluripotency. We found that human IPS cells transfected with a microRNA-145 mutant expressed Sox2 at high levels, allowing iPS to maintain a high level of AP activity in long-term culture and form teratomas in SCID mice. Expression of stem cell markers was increased in iPS transfected with the microRNA-145 mutant, compared with iPS was transfected with microRNA-145. Besides, the expression of Drosha proteins of the microRNA-processor complex, required for the generation of precursor pre-miRNA, was significantly increased in human iPS cells cultured on MEF but not on HuAECs. Taken together, these results suggest that endogenous Sox2 expression may be regulated by microRNA-145 in human iPS cells with HuAECs feeder cells, and Sox2 is a crucial component required for maintenance of them in an undifferentiated, proliferative state capable of self-renewal. Highlights: Black-Right-Pointing-Pointer microRNA-145 inhibits Sox2 expression in human iPS cells. Black-Right-Pointing-Pointer microRNA-145 suppresses the self-renewal and pluripotency of human iPS cells. Black-Right-Pointing-Pointer HuAECs regulate expression of microRNA-145 and Sox2 in human iPS cells. Black-Right-Pointing-Pointer HuAECs feeder

  4. Methods for CT automatic exposure control protocol translation between scanner platforms.

    Science.gov (United States)

    McKenney, Sarah E; Seibert, J Anthony; Lamba, Ramit; Boone, John M

    2014-03-01

    An imaging facility with a diverse fleet of CT scanners faces considerable challenges when propagating CT protocols with consistent image quality and patient dose across scanner makes and models. Although some protocol parameters can comfortably remain constant among scanners (eg, tube voltage, gantry rotation time), the automatic exposure control (AEC) parameter, which selects the overall mA level during tube current modulation, is difficult to match among scanners, especially from different CT manufacturers. Objective methods for converting tube current modulation protocols among CT scanners were developed. Three CT scanners were investigated, a GE LightSpeed 16 scanner, a GE VCT scanner, and a Siemens Definition AS+ scanner. Translation of the AEC parameters such as noise index and quality reference mAs across CT scanners was specifically investigated. A variable-diameter poly(methyl methacrylate) phantom was imaged on the 3 scanners using a range of AEC parameters for each scanner. The phantom consisted of 5 cylindrical sections with diameters of 13, 16, 20, 25, and 32 cm. The protocol translation scheme was based on matching either the volumetric CT dose index or image noise (in Hounsfield units) between two different CT scanners. A series of analytic fit functions, corresponding to different patient sizes (phantom diameters), were developed from the measured CT data. These functions relate the AEC metric of the reference scanner, the GE LightSpeed 16 in this case, to the AEC metric of a secondary scanner. When translating protocols between different models of CT scanners (from the GE LightSpeed 16 reference scanner to the GE VCT system), the translation functions were linear. However, a power-law function was necessary to convert the AEC functions of the GE LightSpeed 16 reference scanner to the Siemens Definition AS+ secondary scanner, because of differences in the AEC functionality designed by these two companies. Protocol translation on the basis of

  5. The ICRP 66 Internal Radiation Exposure Control and Dose Evaluation of The Institute of Nuclear Energy Research

    Energy Technology Data Exchange (ETDEWEB)

    Pang, H. F.; Hwang, W. S.; Chiu, J. H.

    2004-07-01

    The Atomic Energy Council (AEC) is the regulatory body of ionization radiation protection in Taiwan. To effectively control the safety in ionization radiation, AEC brought into force the Ionization Radiation Protection Act on 1 February, 2003 with clear statements of the penalty for violating the Law. The Article 5 of the Act provides: In order to limit the radiation exposure from radiation sources or practices, the Competent Authority shall refer to the latest standards of the International Commission on Radiological Protection to lay down the Safety Standards for Protection against Ionizing Radiation. Thus, AEC is going to draft new safety standards of ionization radiation protection of Taiwan according to ICRP Publication 60. The Institute of Nuclear Energy Research (INER), the governmental institute working on ionization radiation research in Taiwan, took the responsibility of assisting AEC in establishing guidelines on the control of internal radiation exposure and responding to the regulations in the new standards as soon as possible. So, according to the recommendations of ICRP Publications 60, 66,67,68,69,71,78,88, and IAEA Safety Standard Series No. RS-G- 1.1 and 1.2, INER undertook researches on the internal radiation exposure control and dose evaluations for INER's radiation workers as well as dose evaluations for the general public. The research accomplishments not only can be the reference of AEC when making new standards, but also can be followed by other radiation protection businesses. (Author) 23 refs.

  6. Bone morphogenetic protein-7 promotes chondrogenesis in human amniotic epithelial cells.

    Science.gov (United States)

    Zhou, Junjie; Yu, Guangrong; Cao, Chengfu; Pang, Jinhui; Chen, Xianqi

    2011-06-01

    Bone morphogenetic proteins (BMPs) play important roles at multiple stages of chondrogenesis. This study was undertaken to investigate the potential role of bone morphogenetic protein-7 (BMP-7) in the differentiation of chondrocytes using tissue engineering techniques. The impact of BMP-7 on human amniotic epithelial cells (hAECs) was tested. The hAECs were treated either with recombinant human BMP-7 cDNA or with transforming growth factor beta 1 (TGF-β1) as a positive control for three weeks in vitro. Cartilaginous differentiation and proliferation were assayed by quantitative RT-PCR, histology, and in situ hybridization. Our results were such that hAECs treated with either BMP-7 or TGF-β1 expressed cartilage markers (aggrecan, Sox9, CEP-68, and type II and X collagens) within three weeks. Compared with a control vector, BMP-7 induced a decrease in type I collagen expression, while the transcription of the cartilage-specific type II collagen remained stable. In induction experiments, BMP-7 transgenic hAECs exhibited the largest amount of matrix synthesis. In conclusion, these data indicate that BMP-7 plays an important role in inducing the production of cartilage by hAECs in vitro. Cartilage differentiation and matrix maturation can be promoted by BMPs in a cartilage engineering paradigm. These properties make BMPs promising tools in the engineering of cartilaginous joint bio-prostheses and as candidate biological agents or genes for cartilage stabilisation.

  7. Female gonadal shielding with automatic exposure control increases radiation risks

    Energy Technology Data Exchange (ETDEWEB)

    Kaplan, Summer L.; Zhu, Xiaowei [Children' s Hospital of Philadelphia, Department of Radiology, Philadelphia, PA (United States); University of Pennsylvania, Perelman School of Medicine, Philadelphia, PA (United States); Magill, Dennise; Felice, Marc A. [University of Pennsylvania, Environmental Health and Radiation Safety, Philadelphia, PA (United States); Xiao, Rui [University of Pennsylvania, Department of Biostatistics and Epidemiology, Philadelphia, PA (United States); Ali, Sayed [Temple University Hospital, Department of Radiology, Philadelphia, PA (United States)

    2018-02-15

    Gonadal shielding remains common, but current estimates of gonadal radiation risk are lower than estimated risks to colon and stomach. A female gonadal shield may attenuate active automatic exposure control (AEC) sensors, resulting in increased dose to colon and stomach as well as to ovaries outside the shielded area. We assess changes in dose-area product (DAP) and absorbed organ dose when female gonadal shielding is used with AEC for pelvis radiography. We imaged adult and 5-year-old equivalent dosimetry phantoms using pelvis radiograph technique with AEC in the presence and absence of a female gonadal shield. We recorded DAP and mAs and measured organ absorbed dose at six internal sites using film dosimetry. Female gonadal shielding with AEC increased DAP 63% for the 5-year-old phantom and 147% for the adult phantom. Absorbed organ dose at unshielded locations of colon, stomach and ovaries increased 21-51% in the 5-year-old phantom and 17-100% in the adult phantom. Absorbed organ dose sampled under the shield decreased 67% in the 5-year-old phantom and 16% in the adult phantom. Female gonadal shielding combined with AEC during pelvic radiography increases absorbed dose to organs with greater radiation sensitivity and to unshielded ovaries. Difficulty in proper use of gonadal shields has been well described, and use of female gonadal shielding may be inadvisable given the risks of increasing radiation. (orig.)

  8. Female gonadal shielding with automatic exposure control increases radiation risks

    International Nuclear Information System (INIS)

    Kaplan, Summer L.; Zhu, Xiaowei; Magill, Dennise; Felice, Marc A.; Xiao, Rui; Ali, Sayed

    2018-01-01

    Gonadal shielding remains common, but current estimates of gonadal radiation risk are lower than estimated risks to colon and stomach. A female gonadal shield may attenuate active automatic exposure control (AEC) sensors, resulting in increased dose to colon and stomach as well as to ovaries outside the shielded area. We assess changes in dose-area product (DAP) and absorbed organ dose when female gonadal shielding is used with AEC for pelvis radiography. We imaged adult and 5-year-old equivalent dosimetry phantoms using pelvis radiograph technique with AEC in the presence and absence of a female gonadal shield. We recorded DAP and mAs and measured organ absorbed dose at six internal sites using film dosimetry. Female gonadal shielding with AEC increased DAP 63% for the 5-year-old phantom and 147% for the adult phantom. Absorbed organ dose at unshielded locations of colon, stomach and ovaries increased 21-51% in the 5-year-old phantom and 17-100% in the adult phantom. Absorbed organ dose sampled under the shield decreased 67% in the 5-year-old phantom and 16% in the adult phantom. Female gonadal shielding combined with AEC during pelvic radiography increases absorbed dose to organs with greater radiation sensitivity and to unshielded ovaries. Difficulty in proper use of gonadal shields has been well described, and use of female gonadal shielding may be inadvisable given the risks of increasing radiation. (orig.)

  9. The ICRP 66 Internal Radiation Exposure Control and Dose Evaluation of The Institute of Nuclear Energy Research

    International Nuclear Information System (INIS)

    Pang, H. F.; Hwang, W. S.; Chiu, J. H.

    2004-01-01

    The Atomic Energy Council (AEC) is the regulatory body of ionization radiation protection in Taiwan. To effectively control the safety in ionization radiation, AEC brought into force the Ionization Radiation Protection Act on 1 February, 2003 with clear statements of the penalty for violating the Law. The Article 5 of the Act provides: In order to limit the radiation exposure from radiation sources or practices, the Competent Authority shall refer to the latest standards of the International Commission on Radiological Protection to lay down the Safety Standards for Protection against Ionizing Radiation. Thus, AEC is going to draft new safety standards of ionization radiation protection of Taiwan according to ICRP Publication 60. The Institute of Nuclear Energy Research (INER), the governmental institute working on ionization radiation research in Taiwan, took the responsibility of assisting AEC in establishing guidelines on the control of internal radiation exposure and responding to the regulations in the new standards as soon as possible. So, according to the recommendations of ICRP Publications 60, 66,67,68,69,71,78,88, and IAEA Safety Standard Series No. RS-G- 1.1 and 1.2, INER undertook researches on the internal radiation exposure control and dose evaluations for INER's radiation workers as well as dose evaluations for the general public. The research accomplishments not only can be the reference of AEC when making new standards, but also can be followed by other radiation protection businesses. (Author) 23 refs

  10. Female gonadal shielding with automatic exposure control increases radiation risks.

    Science.gov (United States)

    Kaplan, Summer L; Magill, Dennise; Felice, Marc A; Xiao, Rui; Ali, Sayed; Zhu, Xiaowei

    2018-02-01

    Gonadal shielding remains common, but current estimates of gonadal radiation risk are lower than estimated risks to colon and stomach. A female gonadal shield may attenuate active automatic exposure control (AEC) sensors, resulting in increased dose to colon and stomach as well as to ovaries outside the shielded area. We assess changes in dose-area product (DAP) and absorbed organ dose when female gonadal shielding is used with AEC for pelvis radiography. We imaged adult and 5-year-old equivalent dosimetry phantoms using pelvis radiograph technique with AEC in the presence and absence of a female gonadal shield. We recorded DAP and mAs and measured organ absorbed dose at six internal sites using film dosimetry. Female gonadal shielding with AEC increased DAP 63% for the 5-year-old phantom and 147% for the adult phantom. Absorbed organ dose at unshielded locations of colon, stomach and ovaries increased 21-51% in the 5-year-old phantom and 17-100% in the adult phantom. Absorbed organ dose sampled under the shield decreased 67% in the 5-year-old phantom and 16% in the adult phantom. Female gonadal shielding combined with AEC during pelvic radiography increases absorbed dose to organs with greater radiation sensitivity and to unshielded ovaries. Difficulty in proper use of gonadal shields has been well described, and use of female gonadal shielding may be inadvisable given the risks of increasing radiation.

  11. Oxidative generation of guanine radicals by carbonate radicals and their reactions with nitrogen dioxide to form site specific 5-guanidino-4-nitroimidazole lesions in oligodeoxynucleotides.

    Science.gov (United States)

    Joffe, Avrum; Mock, Steven; Yun, Byeong Hwa; Kolbanovskiy, Alexander; Geacintov, Nicholas E; Shafirovich, Vladimir

    2003-08-01

    A simple photochemical approach is described for synthesizing site specific, stable 5-guanidino-4-nitroimidazole (NIm) adducts in single- and double-stranded oligodeoxynucleotides containing single and multiple guanine residues. The DNA sequences employed, 5'-d(ACC CG(1)C G(2)TC CG(3)C G(4)CC) and 5'-d(ACC CG(1)C G(2)TC C), were a portion of exon 5 of the p53 tumor suppressor gene, including the codons 157 (G(2)) and 158 (G(3)) mutation hot spots in the former sequence with four Gs and the codon 157 (G(2)) mutation hot spot in the latter sequence with two Gs. The nitration of oligodeoxynucleotides was initiated by the selective photodissociation of persulfate anions to sulfate radicals induced by UV laser pulses (308 nm). In aqueous solutions, of bicarbonate and nitrite anions, the sulfate radicals generate carbonate anion radicals and nitrogen dioxide radicals by one electron oxidation of the respective anions. The guanine residue in the oligodeoxynucleotide is oxidized by the carbonate anion radical to form the neutral guanine radical. While the nitrogen dioxide radicals do not react with any of the intact DNA bases, they readily combine with the guanine radicals at either the C8 or the C5 positions. The C8 addition generates the well-known 8-nitroguanine (8-nitro-G) lesions, whereas the C5 attack produces unstable adducts, which rapidly decompose to NIm lesions. The maximum yields of the nitro products (NIm + 8-nitro-G) were typically in the range of 20-40%, depending on the number of guanine residues in the sequence. The ratio of the NIm to 8-nitro-G lesions gradually decreases from 3.4 in the model compound, 2',3',5'-tri-O-acetylguanosine, to 2.1-2.6 in the single-stranded oligodeoxynucleotides and to 0.8-1.1 in the duplexes. The adduct of the 5'-d(ACC CG(1)C G(2)TC C) oligodeoxynucleotide containing the NIm lesion in codon 157 (G(2)) was isolated in HPLC-pure form. The integrity of this adduct was established by a detailed analysis of exonuclease digestion

  12. Antidotal Efficacy of a New Combination in Treatment of Subacute T-2 Toxin Poisoning in Rats

    International Nuclear Information System (INIS)

    Jacevic, V. M.; Bocarov-Stancic, A. S.; Resanovic, R. D.; Djordjevic, S. B.; Bokonjic, D. R.

    2007-01-01

    Trichothecene mycotoxin, T-2 toxin is a natural metabolite of Fusarium fungi. T-2 toxin possesses several properties (significant persistence in the environment, cheap manufacture, difficult detection and absence of a specific antidote) that make it a very dangerous potential chemical warfare agent. In our previous experiments, nonsteroidal anti-inflammatory drug (NSAID) nimesulide (NIM), as a selective COX-2 inhibitor, and zeolite absorbent (Min-a-zel Plus, MINplus) administered separately showed a good protective effects against general toxicity induced by T-2 toxin (T2). The aim of this study was to evaluate the antidotal potential of the combination of these two antidotes. T2 was given in a dose of 0.15 mg/kg sc (0.1 LD50), 5 times per week, 4 weeks to adult Wistar rats. Protected animals were given NIM (20 mg/kg im) or/and MINplus (40 mg/kg po) each time immediately after T2. Mortality, general condition, body weight gain, food and water consumption and gut alterations of the animals were registered on a daily basis during 4 weeks. Treatment with NIM or/and MINplus significantly reduced mortality of the rats treated only with T2. Body weight gain, food and water consumption were significantly decreased in T2-treated animals compared to control ones (p < 0.001), what was not the case in the protected rats. In the groups treated with NIM and MINplus gut alterations were significantly less severe than those observed in animals receiving T2 alone (p less than 0.001). These results imply that combined treatment with nimesulide and zeolite absorbent affords a significant protection against subacute T-2 toxin poisoning in rats.(author)

  13. Improving yield and water use efficiency of apple trees through intercrop-mulch of crown vetch (Coronilla varia L.) combined with different fertilizer treatments in the Loess Plateau

    Energy Technology Data Exchange (ETDEWEB)

    Zheng, W.; Li, Y.; Gong, Q.; Zhang, H.; Zhao, Z.; Zheng, Z.; Zhai, B.; Wang, Z.

    2016-07-01

    Improving water use efficiency (WUE) and soil fertility is relevant for apple production in drylands. The effects of intercrop-mulch (IM) of crown vetch (Coronilla varia L.) combined with different fertilizer treatments on WUE of apple trees and soil fertility of apple orchards were assessed over three years (2011, 2013 and 2014). A split-plot design was adopted, in which the main treatments were IM and no intercrop-mulch (NIM). Five sub-treatments were established: no fertilization (CK); nitrogen and phosphorus fertilizer (NP); manure (M); N, P and potassium fertilizer (NPK); and NPK fertilizer combined with manure (NPKM). Due to mowing and mulching each month during July–September, the evapotranspiration for IM was 17.3% lower than that of NIM in the dry year of 2013. Additionally, the soil water storage of NPKM treatment was higher than that of CK during the experimental period. Thus, single fruit weight and fruit number per tree increased with IM and NPKM application. Moreover, applying NPKM with IM resulted in the highest yield (on average of three years), which was 73.25% and 130.51% greater than that of CK in IM and NIM, respectively. The WUE of NPKM combined with IM was also the highest in 2013 and 2014 (47.69 and 56.95% greater than applying IM alone). In addition, due to application of IM combined with NPKM, soil organic matter was increased by 25.8% compared with that of CK (in NIM). Additionally, application of IM combined with NPKM obtained more economic net return, compared to other combinations. Therefore, applying NPKM with IM is recommended for improving apple production in this rain-fed agricultural area.

  14. Controle da infestação por Ornithonyssus sylviarum (Canestrini e Fanzago, 1877 (Acari: Macronyssidae em poedeiras comerciais utilizando extrato de Azadirachta indica Control of Ornithonyssus sylviarum (Canestrini and Fanzago, 1877 (Acari: Macronyssidae infestation in commercial laying hens by using Azadirachta indica extract

    Directory of Open Access Journals (Sweden)

    Nilce M. Soares

    2008-12-01

    Full Text Available O presente trabalho teve por objetivo avaliar a eficácia de um produto à base de extrato de nim, no controle da infestação por O. sylviarum em poedeiras comerciais. O experimento foi realizado observando-se a eficácia do extrato de nim a 2% após duas, três e quatro aplicações com intervalo de sete dias. Os resultados obtidos permitem concluir que o extrato de nim a 2% é efetivo no controle da infestação por O. sylviarum, sendo necessárias pelo menos três pulverizações semanais do produto para que haja o controle efetivo do parasito.This study evaluated the effectiveness of a neem extract-based product to control O. sylviarum infestations in commercial laying hens. The birds were divided in 3 groups, which received 2, 3, or 4 applications of the product at 7 day intervals. The results obtained allow the conclusion that the neem extract at 2"% is effective to control infestations by O. sylviarum, and at least 3 sprays of the product are required weekly for an effective control of the parasite.

  15. [Efficacy of extracts of plants in engorged females of Boophilus microplus from the mesoregion West of Maranhão, Brazil.].

    Science.gov (United States)

    Costa, Francisco B; Vasconcelos, Pádua Suely Da S; Silva, Ana Maria M; Brandão, Vivian M; Da Silva, Iran A; Teixeira, Whaubtyfran C; Guerra, Rita De Maria S N; Dos Santos, Ana Clara G

    2008-09-01

    The objective was to evaluate the efficacy of hydro-alcoholic extracts of nim and citronela at 20% and eucalipto at 10% in Boophilus microplus engorged females collected in cattle naturally infected from the mesoregion West of Maranhão. At the laboratory the females were separated, weighted and distributed in six groups of 10, in duplicate. Each group was immersed in 10mL of the solution of the extracts, for two minutes. In the nim and citronela extracts there was 32% e 17%, respectively, while larval emergence the eucalipto extracts demonstrated 96% of efficacy. In the groups treated by Cipermetrina + Clorpirifós + Citronetal and Deltametrina (positive controls) the mortality occurred after 48h of treatment, while the groups immersed in distilled water (negative control) showed 100% of eggs mass and larval emergence. According to the results, it can be concluded that the extract of eucalipto could be used as acaricide in the control of B. microplus females since it was efficient in vitro, however to nim and citronela showed not efficacy. B. microplus females were not resistant to the chemical compounds used in this experiment.

  16. Twisted boundary states and representation of generalized fusion algebra

    International Nuclear Information System (INIS)

    Ishikawa, Hiroshi; Tani, Taro

    2006-01-01

    The mutual consistency of boundary conditions twisted by an automorphism group G of the chiral algebra is studied for general modular invariants of rational conformal field theories. We show that a consistent set of twisted boundary states associated with any modular invariant realizes a non-negative integer matrix representation (NIM-rep) of the generalized fusion algebra, an extension of the fusion algebra by representations of the twisted chiral algebra associated with the automorphism group G. We check this result for several concrete cases. In particular, we find that two NIM-reps of the fusion algebra for su(3) k (k=3,5) are organized into a NIM-rep of the generalized fusion algebra for the charge-conjugation automorphism of su(3) k . We point out that the generalized fusion algebra is non-commutative if G is non-Abelian and provide some examples for G-bar S 3 . Finally, we give an argument that the graph fusion algebra associated with simple current extensions coincides with the generalized fusion algebra for the extended chiral algebra, and thereby explain that the graph fusion algebra contains the fusion algebra of the extended theory as a subalgebra

  17. Eight-Channel Digital Signal Processor and Universal Trigger Module

    Science.gov (United States)

    Skulski, Wojtek; Wolfs, Frank

    2003-04-01

    A 10-bit, 8-channel, 40 megasamples per second digital signal processor and waveform digitizer DDC-8 (nicknamed Universal Trigger Module) is presented. The digitizer features 8 analog inputs, 1 analog output for a reconstructed analog waveform, 16 NIM logic inputs, 8 NIM logic outputs, and a pool of 16 TTL logic lines which can be individually configured as either inputs or outputs. The first application of this device is to enhance the present trigger electronics for PHOBOS at RHIC. The status of the development and the first results are presented. Possible applications of the new device are discussed. Supported by the NSF grant PHY-0072204.

  18. Digital instrumentation and management of dead time: first results on a NaI well-type detector setup.

    Science.gov (United States)

    Censier, B; Bobin, C; Bouchard, J; Aubineau-Lanièce, I

    2010-01-01

    The LNE-LNHB is engaged in a development program on digital instrumentation, the first step being the instrumentation of a NaI well-type detector set-up. The prototype acquisition card and its technical specifications are presented together with the first comparison with the classical NIM-based acquisition chain, for counting rates up to 100 kcps. The digital instrumentation is shown to be counting-loss free in this range. This validates the main option adopted in this project, namely the implementation of an extending dead time with live-time measurement already successfully used in the MTR2 NIM module developed at LNE-LNHB. Copyright 2010. Published by Elsevier Ltd.

  19. Ventilation design for new plutonium recovery facility

    International Nuclear Information System (INIS)

    Oliver, A.J.; Amos, C.L.

    1975-01-01

    In 1972 the Atomic Energy Commission (AEC) issued revised guidelines on ''Minimum Design Criteria for New Plutonium Facilities.'' With these criteria as guidelines, a new Plutonium Recovery Facility is being designed and constructed at the AEC Rocky Flats Plant. The methods by which the confinement of contamination and air treatment are being handled in this facility are described. (U.S.)

  20. Estimation of effectiveness of automatic exposure control in computed tomograph scanner

    International Nuclear Information System (INIS)

    Akhilesh, Philomina; Sharma, S.D.; Datta, D.; Kulkarni, Arti

    2018-01-01

    With the advent of multiple detector array technology, the use of Computed Tomography (CT) scanning has increase tremendously. Computed Tomography examinations deliver relatively high radiation dose to patients in comparison with conventional radiography. It is therefore required to reduce the dose delivered in CT scans without compromising the image quality. Several parameters like applied potential, tube current, scan length, pitch etc. influence the dose delivered in CT scans. For optimization of patient dose and image quality, all modern CT scanners are enabled with Automatic Exposure Control (AEC) systems. The aim of this work is to compare the dose delivered during CT scans performed with and without AEC in order to estimate the effectiveness of AEC techniques used in CT scanners of various manufacturer

  1. Operational accidents and radiation exposure experience within the United States Atomic Energy Commission, 1943--1975

    International Nuclear Information System (INIS)

    1975-01-01

    The occupational injury and fatality experience during 32 years of the development of the atomic energy industry under the direction of the Atomic Energy Commission (AEC) and its predecessor, the Manhattan Engineering District, is reviewed. Data are included on the cause of all accidents, including fires and transportation accidents, and the cost of AEC property damage. Fatalities of AEC and contractor personnel from all causes during the 32-year period totaled 321, of which 184 occurred in construction; 121 in AEC operations such as production, research, and services; and 16 in Government functions. There were 19,225 lost-time injuries attributable to all accidental causes, or a 32-year frequency rate of 2.75 based on the number of injuries per million man-hours. There were six deaths attributable to nuclear causes, thee of which were due to blast and flying missiles and three caused by whole-body radiation exposure. Forty-one workers were involved in lost-time radiation accidents, of whom 26 showed clinical manifestations attributable to radiation, resulting in permanent partial-disability of three workers and the loss of a digit by four workers, while the others did not develop evidence of radiation injury

  2. PENGEMBANGAN PROGRAM PENDIDIKAN DI SD ISLAM INTERNASIONAL AL-ABIDIN SURAKARTA DALAM MENGHADAPI MEA

    Directory of Open Access Journals (Sweden)

    Tsabita Fiki Amalia

    2016-12-01

    Full Text Available ASEAN Economic Community (AEC ia an integratied system of the countries in Southeast Asia that enable and facilitate the free trade system. Since 2015 the AEC has been officially started, and many foreign companies has been opened in Indonesia. However, the quality of Human Resources (HR in Indonesia is lacking to confront AEC’s system. It can be seen from the number of unemployed people in Indonesia and Indonesian citizen education level is still low. This shows a lack of quality in education. Departing from this problem, the authors conducted research at the international elementary school, SDII Al Abidin Surakarta. This school has excellent programs that can be developed and replicated in order to improve the quality of Human Resources (HR since elementary school. This research aims to study programs that are run in order to deal with AEC. This research was conducted with a qualitative descriptive method by collecting data through interviews, observation, and documentation. The results showed some excellent programs that are owned by SDII Al Abidin Surakarta which can be used as a weapon to face the ASEAN Economic Community (AEC. The programs are international curriculum, three varians grade programs, and extracurricular.

  3. Amniotic epithelial stem cell biocompatibility for electrospun poly(lactide-co-glycolide), poly(ε-caprolactone), poly(lactic acid) scaffolds

    Energy Technology Data Exchange (ETDEWEB)

    Russo, Valentina [Faculty of Veterinary Medicine, University of Teramo, Campus Universitario Coste S. Agostino Via R. Balzarini 1, 64100 Teramo (Italy); StemTeCh Group (Italy); Tammaro, Loredana [Department of Industrial Engineering, University of Salerno, Via Giovanni Paolo II 132, 84084 Fisciano, SA (Italy); Di Marcantonio, Lisa, E-mail: ldimarcantonio@unite.it [Faculty of Veterinary Medicine, University of Teramo, Campus Universitario Coste S. Agostino Via R. Balzarini 1, 64100 Teramo (Italy); Sorrentino, Andrea [Institute for Polymers, Composite and Biomaterials (IPCB), CNR, P.le Enrico Fermi 1, I-80055 Portici, Napoli (Italy); Ancora, Massimo [Istituto Zooprofilattico Sperimentale dell' Abruzzo e del Molise ‘G. Caporale’, Teramo (Italy); Valbonetti, Luca [Faculty of Veterinary Medicine, University of Teramo, Campus Universitario Coste S. Agostino Via R. Balzarini 1, 64100 Teramo (Italy); StemTeCh Group (Italy); Turriani, Maura; Martelli, Alessandra [Faculty of Veterinary Medicine, University of Teramo, Campus Universitario Coste S. Agostino Via R. Balzarini 1, 64100 Teramo (Italy); Cammà, Cesare [Istituto Zooprofilattico Sperimentale dell' Abruzzo e del Molise ‘G. Caporale’, Teramo (Italy); Barboni, Barbara [Faculty of Veterinary Medicine, University of Teramo, Campus Universitario Coste S. Agostino Via R. Balzarini 1, 64100 Teramo (Italy); StemTeCh Group (Italy)

    2016-12-01

    Three biodegradable thermoplastic polymers, poly(ε-caprolactone) (PCL), poly(L-lactide-co-D,L-lactide) (PLA) and poly(L-lactide-co-glycolide) (PLGA), have been used to produce nonwovens scaffolds with uniform micrometer fibres. Scaffolds' physical and morphological characterization was performed by X-ray diffraction, Scanning Electron Microscopy and Contact-Angle test. Morphological investigations revealed that all produced fibres were randomly orientated with interconnected pores ranging between 5 and 12 μm in diameter. An average fibre diameter of 1.5, 0.75 and 1.2 μm was found for PCL, PLA and PLGA, respectively. Moreover, experiments were designed to verify whether the fabricated electrospun substrates were biocompatible for ovine amniotic epithelial stem cells (oAECs) under in vitro conditions. Cell adhesion, survival, spatial organization on fibres, proliferation index, and DNA quantification after 48 h culture, showed an enhanced adhesion and proliferation, especially for PLGA scaffolds. The favourable interaction between oAECs and the fibrous scaffolds was attributed to the greatly improved porosity and pore size distribution of the electrospun scaffolds. In addition, AECs can be considered ideal for tissue engineering especially when using biocompatible and opportunely produced scaffolds. - Highlights: • Scaffolds have random oriented, beadless fibres and similar wettability. • Porosity and pore size distribution are determinant on boosting cell activity. • oAECs activities are influenced by scaffold chemical and physical structure. • In PLGA oAECs showed higher spatial distribution efficiency. • PLGA seeded cells present a rise in cell proliferation activity and in DNA amount.

  4. The effect of magnetic substorms on near-ground atmospheric current

    Directory of Open Access Journals (Sweden)

    E. Belova

    2000-12-01

    Full Text Available Ionosphere-magnetosphere disturbances at high latitudes, e.g. magnetic substorms, are accompanied by energetic particle precipitation and strong variations of the ionospheric electric fields and currents. These might reasonably be expected to modify the local atmospheric electric circuit. We have analysed air-earth vertical currents (AECs measured by a long wire antenna at Esrange, northern Sweden during 35 geomagnetic substorms. Using superposed epoch analysis we compare the air-earth current variations during the 3 h before and after the time of the magnetic X-component minimum with those for corresponding local times on 35 days without substorms. After elimination of the average daily variation we can conclude that the effect of substorms on AEC is small but distinguishable. It is speculated that the AEC increases observed during about 2 h prior to the geomagnetic X-component minimum, are due to enhancement of the ionospheric electric field. During the subsequent 2 h of the substorm recovery phase, the difference between "substorm" and "quiet" atmospheric currents decreases. The amplitude of this "substorm" variation of AEC is estimated to be less than 50% of the amplitude of the diurnal variation in AEC during the same time interval. The statistical significance of this result was confirmed using the Van der Waerden X-test. This method was further used to show that the average air-earth current and its fluctuations increase during late expansion and early recovery phases of substorms.Key words: Ionosphere (electric fields and currents · Magnetospheric physics (storms and substorms · Meteorology and atmospheric dynamics (atmospheric electricity

  5. Safety and security of radioactive sources in Taiwan

    International Nuclear Information System (INIS)

    Tsay Yeousong; Guan Channan; Cheng Yungfu

    2008-01-01

    In Taiwan, the safety and security of radioactive sources is a high priority issue. Ionizing Radiation Protection Act (IRPA) and correlating regulations had been in place for effective control of the safety and security of radioactive sources since 2003. For increased control of sealed radioactive sources, Atomic Energy Council (AEC) established in March 2004 an online reporting system through the Internet, assisting source owners in reporting their sources every month. To conform to the Code of Conduct on the Safety and Security of Radioactive Sources and the Categorization of radioactive sources, published by the International Atomic Energy Agency (IAEA), AEC has taken the following actions: 1. Established an inventory of Categories 1 and 2 radioactive sources, and implemented the Import/Export Provisions of the Code. 2. Required that each licensee shall control access to Categories 1 and 2 radioactive sources, and AEC will conduct project inspection on Categories 1 and 2 radioactive sources. 3. Using a new radiation warning symbol by ISO for Categories 1 and 2 radioactive sources. The reinforcement of orphaned source control was implemented as early as 1995. All steel mills have installed radiation detectors to scan incoming metal scrap to prevent accidental smelting of radioactive sources. The results of this effort will be discussed in the paper. The above measures are examples for demonstrating AEC's commitment to reinforced control of radioactive sources. AEC will continue to protect public safety and security, ensuring that Taiwan's regulatory system in radiation protection conforms to international standards. (author)

  6. Automatic exposure control systems designed to maintain constant image noise: effects on computed tomography dose and noise relative to clinically accepted technique charts.

    Science.gov (United States)

    Favazza, Christopher P; Yu, Lifeng; Leng, Shuai; Kofler, James M; McCollough, Cynthia H

    2015-01-01

    To compare computed tomography dose and noise arising from use of an automatic exposure control (AEC) system designed to maintain constant image noise as patient size varies with clinically accepted technique charts and AEC systems designed to vary image noise. A model was developed to describe tube current modulation as a function of patient thickness. Relative dose and noise values were calculated as patient width varied for AEC settings designed to yield constant or variable noise levels and were compared to empirically derived values used by our clinical practice. Phantom experiments were performed in which tube current was measured as a function of thickness using a constant-noise-based AEC system and the results were compared with clinical technique charts. For 12-, 20-, 28-, 44-, and 50-cm patient widths, the requirement of constant noise across patient size yielded relative doses of 5%, 14%, 38%, 260%, and 549% and relative noises of 435%, 267%, 163%, 61%, and 42%, respectively, as compared with our clinically used technique chart settings at each respective width. Experimental measurements showed that a constant noise-based AEC system yielded 175% relative noise for a 30-cm phantom and 206% relative dose for a 40-cm phantom compared with our clinical technique chart. Automatic exposure control systems that prescribe constant noise as patient size varies can yield excessive noise in small patients and excessive dose in obese patients compared with clinically accepted technique charts. Use of noise-level technique charts and tube current limits can mitigate these effects.

  7. CCR2 and CXCR3 agonistic chemokines are differently expressed and regulated in human alveolar epithelial cells type II

    Directory of Open Access Journals (Sweden)

    Prasse Antje

    2005-07-01

    Full Text Available Abstract The attraction of leukocytes from circulation to inflamed lungs depends on the activation of both the leukocytes and the resident cells within the lung. In this study we determined gene expression and secretion patterns for monocyte chemoattractant protein-1 (MCP-1/CCL2 and T-cell specific CXCR3 agonistic chemokines (Mig/CXCL9, IP-10/CXCL10, and I-TAC/CXCL11 in TNF-α-, IFN-γ-, and IL-1β-stimulated human alveolar epithelial cells type II (AEC-II. AEC-II constitutively expressed high level of CCL2 mRNA in vitro and in situ , and released CCL2 protein in vitro . Treatment of AEC-II with proinflammatory cytokines up-regulated both CCL2 mRNA expression and release of immunoreactive CCL2, whereas IFN-γ had no effect on CCL2 release. In contrast, CXCR3 agonistic chemokines were not detected in freshly isolated AEC-II or in non-stimulated epithelial like cell line A549. IFN-γ, alone or in combination with IL-1β and TNF-α resulted in an increase in CXCL10, CXCL11, and CXCL9 mRNA expression and generation of CXCL10 protein by AEC-II or A549 cells. CXCL10 gene expression and secretion were induced in dose-dependent manner after cytokine-stimulation of AEC-II with an order of potency IFN-γ>>IL-1β ≥ TNF-α. Additionally, we localized the CCL2 and CXCL10 mRNAs in human lung tissue explants by in situ hybridization, and demonstrated the selective effects of cytokines and dexamethasone on CCL2 and CXCL10 expression. These data suggest that the regulation of the CCL2 and CXCL10 expression exhibit significant differences in their mechanisms, and also demonstrate that the alveolar epithelium contributes to the cytokine milieu of the lung, with the ability to respond to locally generated cytokines and to produce potent mediators of the local inflammatory response.

  8. The effect of epoch length on estimated EEG functional connectivity and brain network organisation

    Science.gov (United States)

    Fraschini, Matteo; Demuru, Matteo; Crobe, Alessandra; Marrosu, Francesco; Stam, Cornelis J.; Hillebrand, Arjan

    2016-06-01

    Objective. Graph theory and network science tools have revealed fundamental mechanisms of functional brain organization in resting-state M/EEG analysis. Nevertheless, it is still not clearly understood how several methodological aspects may bias the topology of the reconstructed functional networks. In this context, the literature shows inconsistency in the chosen length of the selected epochs, impeding a meaningful comparison between results from different studies. Approach. The aim of this study was to provide a network approach insensitive to the effects that epoch length has on functional connectivity and network reconstruction. Two different measures, the phase lag index (PLI) and the amplitude envelope correlation (AEC) were applied to EEG resting-state recordings for a group of 18 healthy volunteers using non-overlapping epochs with variable length (1, 2, 4, 6, 8, 10, 12, 14 and 16 s). Weighted clustering coefficient (CCw), weighted characteristic path length (L w) and minimum spanning tree (MST) parameters were computed to evaluate the network topology. The analysis was performed on both scalp and source-space data. Main results. Results from scalp analysis show a decrease in both mean PLI and AEC values with an increase in epoch length, with a tendency to stabilize at a length of 12 s for PLI and 6 s for AEC. Moreover, CCw and L w show very similar behaviour, with metrics based on AEC more reliable in terms of stability. In general, MST parameters stabilize at short epoch lengths, particularly for MSTs based on PLI (1-6 s versus 4-8 s for AEC). At the source-level the results were even more reliable, with stability already at 1 s duration for PLI-based MSTs. Significance. The present work suggests that both PLI and AEC depend on epoch length and that this has an impact on the reconstructed network topology, particularly at the scalp-level. Source-level MST topology is less sensitive to differences in epoch length, therefore enabling the comparison of brain

  9. Stress test of the nuclear power plants performed in Taiwan

    International Nuclear Information System (INIS)

    Wu, C.H.; Teng, W.C.; Chang, S.; Chen, Y.B.

    2014-01-01

    In the wake of Japan's Fukushima Daiichi Nuclear Power Plants event, the Atomic Energy Council (AEC) has asked Taiwan's Nuclear Power Plant operator (TPC) to re-examine and re-evaluate the vulnerabilities of its nuclear units, and furthermore, take possible countermeasures against extreme natural disasters, including earthquake, tsunami and rock-and-mud slide. The evaluation process should be based on both within and beyond Design Basis Accidents, by reference to the actions recommended by the world nuclear authorities and groups, namely, IAEA, USNRC, NEI, ENSREG and WANO. Taiwan is a very densely populated region of the world. Furthermore, like Japan, due to its geophysical position, Taiwan is prone to large scale earthquakes, and although historically rare, Taiwan also faces the potential risk of tsunamis. AEC also asked TPC to perform the stress test following the specification given by WENRA (later ENSREG) and conducted in all the EU's nuclear reactors. After completion of the stress test for all the nuclear power plants, AEC was trying to have the reports peer reviewed by international organizations, as EU did. The OECD/NEA accepted AEC's request and formed a review team specific to the review of Taiwan's National Report for the Stress Test. There were 18 follow-up items after the NEA's review. Based on these items, AEC developed five orders to require TPC further enhancing their capabilities to cope with extreme natural hazards. The ENSREG also formed a nine-expert review team for Taiwan's Stress Test in response to AEC's request almost at the same time as the OECD/NEA. The ENSREG review team began their works in June 2013 by desktop review, and ended in early October 2013 by country visit to Taiwan. While the assessment of post-Fukushima evaluation reveals neither immediate nuclear safety concerns nor threats to the public health and safety, AEC requested that TPC focus on strengthening its re-evaluation on design

  10. Stress test of the nuclear power plants performed in Taiwan

    Energy Technology Data Exchange (ETDEWEB)

    Wu, C.H.; Teng, W.C.; Chang, S.; Chen, Y.B. [Atomic Energy Council, Taipei, Taiwan (China)

    2014-07-01

    In the wake of Japan's Fukushima Daiichi Nuclear Power Plants event, the Atomic Energy Council (AEC) has asked Taiwan's Nuclear Power Plant operator (TPC) to re-examine and re-evaluate the vulnerabilities of its nuclear units, and furthermore, take possible countermeasures against extreme natural disasters, including earthquake, tsunami and rock-and-mud slide. The evaluation process should be based on both within and beyond Design Basis Accidents, by reference to the actions recommended by the world nuclear authorities and groups, namely, IAEA, USNRC, NEI, ENSREG and WANO. Taiwan is a very densely populated region of the world. Furthermore, like Japan, due to its geophysical position, Taiwan is prone to large scale earthquakes, and although historically rare, Taiwan also faces the potential risk of tsunamis. AEC also asked TPC to perform the stress test following the specification given by WENRA (later ENSREG) and conducted in all the EU's nuclear reactors. After completion of the stress test for all the nuclear power plants, AEC was trying to have the reports peer reviewed by international organizations, as EU did. The OECD/NEA accepted AEC's request and formed a review team specific to the review of Taiwan's National Report for the Stress Test. There were 18 follow-up items after the NEA's review. Based on these items, AEC developed five orders to require TPC further enhancing their capabilities to cope with extreme natural hazards. The ENSREG also formed a nine-expert review team for Taiwan's Stress Test in response to AEC's request almost at the same time as the OECD/NEA. The ENSREG review team began their works in June 2013 by desktop review, and ended in early October 2013 by country visit to Taiwan. While the assessment of post-Fukushima evaluation reveals neither immediate nuclear safety concerns nor threats to the public health and safety, AEC requested that TPC focus on strengthening its re-evaluation on design

  11. Transcriptomic profiling of primary alveolar epithelial cell differentiation in human and rat

    Directory of Open Access Journals (Sweden)

    Crystal N. Marconett

    2014-12-01

    Full Text Available Cell-type specific gene regulation is a key to gaining a full understanding of how the distinct phenotypes of differentiated cells are achieved and maintained. Here we examined how changes in transcriptional activation during alveolar epithelial cell (AEC differentiation determine phenotype. We performed transcriptomic profiling using in vitro differentiation of human and rat primary AEC. This model recapitulates in vitro an in vivo process in which AEC transition from alveolar type 2 (AT2 cells to alveolar type 1 (AT1 cells during normal maintenance and regeneration following lung injury. Here we describe in detail the quality control, preprocessing, and normalization of microarray data presented within the associated study (Marconett et al., 2013. We also include R code for reproducibility of the referenced data and easily accessible processed data tables.

  12. 1974 annual report to Congress. Part one: operating and developmental functions. Part two: regulatory functions

    International Nuclear Information System (INIS)

    1974-01-01

    This report is of a nontechnical nature, with numerous photographs. The first part contains chapters on the reorganization of the AEC to ERDA and NRC, the history of the AEC: 1946--1975, energy research and development, breeder reactors, public health and safety, fusion research, environmental research, biomedical research, physical research, nuclear materials, national security, and management of radioactive waste. The part on regulatory functions contains chapters on nuclear regulation in 1974, 1974 nuclear power licensing, fuels and materials licensing, nuclear materials and plant protection, regulatory operations, nuclear standards development, public participation in regulation, and state and international liaison. Appendixes give membership of various boards and committees, changes in rules and regulations, a list of AEC regulatory guides, and a table of nuclear electric generating units in operation, under construction, or planned. (U.S.)

  13. Experimental verification of the inverse Doppler effect in negative-index material

    Science.gov (United States)

    Feng, Lie; Chen, Jiabi; Wang, Yan; Geng, Tao; Zhuang, Songlin

    2010-10-01

    μResearch of negative-index material (NIM) is a very hot developing research field in recent years. NIM is also called left-handed material (LHM), in which the electric field [see manuscript], the magnetic field [see manuscript] and the wave vector [see manuscript] are not composed of a set of right-handed coordinates but a set of left-handed coordinates. Thus the action of electromagnetic waves in both left-handed material and right-handed material is just the opposite, for instance, the negative refraction phenomenon, the inverse Doppler effect and so on. Here we report the explicit result of the inverse Doppler effect through a photonic crystal (PC) prism at 10.6m wavelength for the first time, and the result we get from the experiment is much similar to the theoretical analysis we have deduced before. During the experiment, the CO2 laser is used as a light source, and the PC prism is used as a sample, which can move a tiny distance (1mm) uniformly with a translating stage. Based on the method of optical heterodyne, we let the emergent light from the output surface of PC prism and the reference light from light source interfere at the surface of the detector. When the translating stage moves towards the detector, the optical paths in the PC prism will be changed, and then the Doppler frequency shift will be generated. Though several different samples have been tested repeatedly, the results we get are extraordinarily similar. So we can be sure that the inverse Doppler effect really exists in the NIM at optical frequencies. To our best knowledge, this is the only experimental verification of the inverse Doppler effect in the NIM at optical frequencies at home and aboard.

  14. Improving the Effectiveness of Penicillin Allergy De-labeling.

    Science.gov (United States)

    Bourke, Jack; Pavlos, Rebecca; James, Ian; Phillips, Elizabeth

    2015-01-01

    Approximately 10-20% of hospitalized patients are labeled as penicillin allergic, and this is associated with significant health and economic costs. We looked at the effectiveness of penicillin allergy de-labeling in clinical practice with the aim of deriving risk stratification models to guide testing strategies. Consecutive patients aged 15 years or more, referred to a Western Australian public hospital drug allergy service between 2008 and 2013 for beta-lactam allergy, were included. Follow-up surveys were conducted. Results of skin prick testing and intradermal testing (SPT/IDT) and oral challenge (OC), and follow-up of post testing antibiotic usage were the main outcomes. SPT/IDT was performed in 401 consecutive patients with immediate (IMM) (≤ 1 hour) (n = 151) and nonimmediate (NIM) (>1 hour) (n = 250) reactions. Of 341 patients, 42 (12.3%) were SPT/IDT+ to ≥ 1 penicillin reagents, including 35/114 (30.4%) in the IMM group and 7/227 (3.1%) in the NIM group (P penicillin VK (SPT/IDT negative predictive value [NPV] 99.2%). Selective or unrestricted beta-lactam was recommended in almost 90% overall, including 238/250 (95.2%) in the NIM group and 126/151 (83.4%) in the IMM group (P = .0001). Of 182 patients, 137 (75.3%) were following the allergy label modifications (ALM) at the time of follow-up. Penicillin SPT/IDT/OC safely de-labels penicillin-allergic patients and identifies selective beta-lactam allergies; however, incomplete adherence to ALM recommendations impairs effectiveness. Infrequent SPT/IDT+ and absent OC reactions in patients with NIM reactions suggest OC alone to be a safe and cost-effective de-labeling strategy that could improve the coverage of penicillin allergy de-labeling in lower risk populations. Copyright © 2015 American Academy of Allergy, Asthma & Immunology. Published by Elsevier Inc. All rights reserved.

  15. A high resolution portable spectroscopy system

    International Nuclear Information System (INIS)

    Kulkarni, C.P.; Vaidya, P.P.; Paulson, M.; Bhatnagar, P.V.; Pande, S.S.; Padmini, S.

    2003-01-01

    Full text: This paper describes the system details of a High Resolution Portable Spectroscopy System (HRPSS) developed at Electronics Division, BARC. The system can be used for laboratory class, high-resolution nuclear spectroscopy applications. The HRPSS consists of a specially designed compact NIM bin, with built-in power supplies, accommodating a low power, high resolution MCA, and on-board embedded computer for spectrum building and communication. A NIM based spectroscopy amplifier and a HV module for detector bias are integrated (plug-in) in the bin. The system communicates with a host PC via a serial link. Along-with a laptop PC, and a portable HP-Ge detector, the HRPSS offers a laboratory class performance for portable applications

  16. Role of the Atomic Energy Commission

    Energy Technology Data Exchange (ETDEWEB)

    Oakley, W L [U.S. Atomic Energy Commission, Germantown, MD (United States)

    1969-07-01

    Public health aspects of nuclear explosions fall into two categories: (1) operational safety during the conduct of the explosion; and (2) the regulation of by-product material resulting from the explosion. By statute, the AEC has the responsibility for both assuring operational safety and regulating by-product material. Current AEC safety and regulatory practices are described; future problems or needs discussed; and relationship to federal, state and local governments outlined. (author)

  17. Role of the Atomic Energy Commission

    International Nuclear Information System (INIS)

    Oakley, W.L.

    1969-01-01

    Public health aspects of nuclear explosions fall into two categories: (1) operational safety during the conduct of the explosion; and (2) the regulation of by-product material resulting from the explosion. By statute, the AEC has the responsibility for both assuring operational safety and regulating by-product material. Current AEC safety and regulatory practices are described; future problems or needs discussed; and relationship to federal, state and local governments outlined. (author)

  18. Tartu noored akordionistid tegid Prantsusmaal ilma / Endel Jukk

    Index Scriptorium Estoniae

    Jukk, Endel

    2004-01-01

    36. noorte akordionistide konkursil Pariisi eeslinnas Argenteuil'is saavutas karika Tambet Anja Elleri nim. Tartu Muusikakoolist (õpetaja Uno Arro) ja kuldmedali Liis Jõgar Luunjast (õpetaja Lehte Anja)

  19. Театральная радуга в городе белых ночей / Борис Тух

    Index Scriptorium Estoniae

    Тух, Борис, 1946-

    2015-01-01

    16. teatrifestival Vikerkaar toimus Peterburis mais-juunis 2015, korraldas Aleksandr Brjantsevi nimeline Noorsooteater. Pikemalt Brjantsevi nim. Noorsooteatri lavastusest Ray Bradbury romaani "Võilillevein" ainetel (lavastaja Adolf Šapiro)

  20. List of unrestricted NIM reports and papers published during the first decade of NIM'S existence (1966 to 1975)

    International Nuclear Information System (INIS)

    Paynter, J.C.; Glen, H.W.

    1976-01-01

    This publication lists the 554 unrestricted reports and 200 papers published by the National Institute for Metallurgy during the first ten years of its existence. For ease of reference, these publications are also classified under the research programmes that gave rise to them [af

  1. A review of the AEC in Pakistan

    International Nuclear Information System (INIS)

    Faruqui, A.M.

    1972-01-01

    In September this year the Pakistan Atomic Energy Commission completed six years of working with nuclear energy. Its expansion in all fields, both in research and practical application, has shown remarkable progress. This outline has been specially written by Mr. Akhtar Mahmud Faruqui, Director, Scientific Information and Public Relations, PAEC. (author)

  2. Command and Control for Homeland Security

    National Research Council Canada - National Science Library

    Greene, Marjorie

    2007-01-01

    ... Security June 2006, NIMS Revision Version 2 March 2007, NWDC Domestic Disaster Relief Operations Planning, 15 May 2006, AFRL-Supported Studies on Large- Scale Coordination, A Sociotechnical Systems...

  3. Mozhet kontshitsja, no ne "Vishnjovõi sad" / Jelena Skulskaja

    Index Scriptorium Estoniae

    Skulskaja, Jelena, 1950-

    2008-01-01

    Vene teatrifestivali "Kuldne mask Eestis" viimasest etendusest, Anton Tshehhovi "Kirsiaiast" Eimuntas Nekroshiuse lavastuses. Lavastus sündis K. Stanislavski nim. Rahvusvahelise Fondi ja teatri Meno Fortas ühisprojektina

  4. Lastekirjanduse uurimisest laias maailmas / Mare Müürsepp

    Index Scriptorium Estoniae

    Müürsepp, Mare

    1995-01-01

    Organisatsiooni International Research Society for Children's Literature (IRSCL, asutatud 1969. a.) tegevusest ja muljeid 1993. a. kongressist Austraalias. Sisaldab ka IRSCL-i väljaannete loetelu (8 nim.)

  5. Department of Energy (DOE) system for the transportation of strategic quantities of special nuclear material (SQ SNM)

    International Nuclear Information System (INIS)

    Dickason, D.P.

    1978-01-01

    Since 1947 DOE and its predecessor agencies, AEC and ERDA, have moved nuclear materials by a variety of commercial and government transportation modes. In the late 1960's world-wide terrorism and other dissident activities prompted the then-AEC to review its procedures for safeguarding SNM. These reviews resulted in immediate and long-range programs for improvement of overall safeguards. Domestic transportation of completed nuclear weapons and SNM used in the weapons program was selected for special consideration. In the early 1970's AEC started the development of a Safe Secure Trailer (SST) to transport nuclear weapons and nuclear components and the development and installation of a high frequency (HF) communications system to assure continuous radio contact between selected highway and rail shipments and Headquarters, Albuquerque Operations (ALO). Late 1974 AEC directed ALO to develop a transportation system to extend weapons-level protection to all AEC SQ SNM shipments and to consolidate, manage, and operate this system. As of September 1976 all SQ SNM was being transported in the Safe Secure DOE (then ERDA) transportation safeguards system, composed of the following principal elements: (1) Transport equipment consisting of Safe Secure Trailers and specially modified towing tractors; Safe Secure Railcars and specially modified escort coaches; and specially designed highway escort vehicles. (2) An automated high-frequency digital radio system that enables continuous communications between the transporting equipment and central control. (3) A courier force that operates all transport equipment (except aircraft and rail power units) and mobile communications equipment; provides armed protection for shipments; and assures proper safety en route. (4) A central Headquarters staff that plans, executes, and controls shipments and directs, manages, and operates the system

  6. Neutrophil Extracellular DNA Traps Induce Autoantigen Production by Airway Epithelial Cells

    Directory of Open Access Journals (Sweden)

    Youngwoo Choi

    2017-01-01

    Full Text Available The hypothesis of autoimmune involvement in asthma has received much recent interest. Autoantibodies, such as anti-cytokeratin (CK 18, anti-CK19, and anti-α-enolase antibodies, react with self-antigens and are found at high levels in the sera of patients with severe asthma (SA. However, the mechanisms underlying autoantibody production in SA have not been fully determined. The present study was conducted to demonstrate that neutrophil extracellular DNA traps (NETs, cytotoxic molecules released from neutrophils, are a key player in the stimulation of airway epithelial cells (AECs to produce autoantigens. This study showed that NETs significantly increased the intracellular expression of tissue transglutaminase (tTG but did not affect that of CK18 in AECs. NETs induced the extracellular release of both tTG and CK18 in a concentration-dependent manner. Moreover, NETs directly degraded intracellular α-enolase into small fragments. However, antibodies against neutrophil elastase (NE or myeloperoxidase (MPO attenuated the effects of NETs on AECs. Furthermore, each NET isolated from healthy controls (HC, nonsevere asthma (NSA, and SA had different characteristics. Taken together, these findings suggest that AECs exposed to NETs may exhibit higher autoantigen production, especially in SA. Therefore, targeting of NETs may represent a new therapy for neutrophilic asthma with a high level of autoantigens.

  7. Small and Local until it hurts? -Architects and Engineers development in a Professional knowledge industry

    DEFF Research Database (Denmark)

    Koch, Christian; Buser, Martine

    2009-01-01

    professional knowledge service AEC-companies in the region of Central Denmark. The aim of the paper is to analyse how SMEs is managed, is innovating, using ICT and their response to the financial crisis.   Drawing on management studies, professional knowledge service is viewed as something precariously...... constructed through interacting with customers. An extensive desk study and two interviews are used to investigate the local AEC-companies, focusing on two micro firms. There is considerable growth among knowledge service companies in the region. The analysis shows that microfirms are indeed distinct......, innovation for example occurs in a complex interplay with limited internal efforts and external networking. And still as a relatively local phenomenon. Even if the financial crisis has considerably impact of the AEC-sector in 2008-9, the microfirms investigated still haven't been impacted and the pain...

  8. Computed tomography of head: impact of the use of automatic exposure control

    International Nuclear Information System (INIS)

    Souza, Giordana Salvi de Souza; Froner, Ana Paula Pastre; Silva, Ana Maria Marques da

    2017-01-01

    The use of dose reduction systems in computed tomography is particularly important for pediatric patients, who have a high radiosensitivity, since they are in the growing phase. The aim of this study was to evaluate the impact of Siemens AEC Care Dose system use on dose estimation in head computed tomography scans in pediatric patients. A retrospective study was conducted with 199 computed tomography head scans of pediatric patients, divided in different age groups, on a 16-channel Siemens Emotion scanner. It was possible to observe, for all age groups, that the use of AEC Care Dose system, not only reduced CTDI vol , but also the interquartile range, reducing the total dose in the investigated population. Concluding, AEC Care Dose system models the tube current according to the patient's dimensions, reducing individual and collective dose without affecting the diagnostic quality . (author)

  9. Zdorovje - eto zhizn võssokogo katshestva / Jekaterina Sokolovskaja

    Index Scriptorium Estoniae

    Sokolovskaja, Jekaterina

    2004-01-01

    Venemaa meditsiiniteaduste akadeemia inimeseökoloogia ja keskkonnahügieeni A. N. Sõssina nim. teadusliku uurimise instituudi andmetel on viimase kümne aasta jooksul keskkonna seisund Venemaal paranenud

  10. Plasmon-Enhanced Photonic Crystal Negative Index Materials for Superlensing Applications, Phase I

    Data.gov (United States)

    National Aeronautics and Space Administration — Negative index materials (NIMs) offer tremendous potential for the formation of highly compact as well as large-area deployable thin-film optical components. Omega...

  11. "Thais" muusika on fenomenaalne / Veronika Džiojeva ; intervjueerinud Silja Joon

    Index Scriptorium Estoniae

    Džiojeva, Veronika

    2009-01-01

    Küsimustele vastab 22. mail Pärnu Endla teatris esietenduva Jules Massenet' ooperi "Thais" nimiosatäitja, 2007. aastal toimunud Klaudia Taevi nim. rahvusvahelise ooperilauljate konkursi laureaat Veronika Džiojeva

  12. "Hair" - laul ja tants, mitte kultusmuusikal / Andris Feldmanis

    Index Scriptorium Estoniae

    Feldmanis, Andris, 1982-

    2006-01-01

    Kultusmuusikal "Hair" Rock Cafés Georg Otsa nim. Tallinna Muusikakooli õpilaste esituses, lavastaja Ivo Eensalu, muusikajuhid Mare Väljataga, Meelis Punder, tantsujuht Ulrike Ustav, kunstnikud Kristel Viks, Liisi Suuroja

  13. German, Pikovaja dama i jejo alter ego / Ksenia Repson

    Index Scriptorium Estoniae

    Repson, Ksenia

    2007-01-01

    Moskva Vahtangovi nim. Teatri näitlejad Ludmilla Maksakova, Jevgeni Knjazev ja Julia Rutberg räägivad Pjotr Fomenko "Padaemanda" lavastusest, mis etendub Tallinnas festivali "Kuldne mask Eestis" raames

  14. Different therapeutic effects of cells derived from human amniotic membrane on premature ovarian aging depend on distinct cellular biological characteristics.

    Science.gov (United States)

    Ding, Chenyue; Li, Hong; Wang, Yun; Wang, Fuxin; Wu, Huihua; Chen, Rulei; Lv, Jinghuan; Wang, Wei; Huang, Boxian

    2017-07-27

    Many reports have shown that various kinds of stem cells have the ability to recover premature ovarian aging (POA) function. Transplantation of human amniotic epithelial cells (hAECs) improves ovarian function damaged by chemotherapy in a mice model. Understanding of how to evaluate the distinct effects of adult stem cells in curing POA and how to choose stem cells in clinical application is lacking. To build a different degrees of POA model, mice were administered different doses of cyclophosphamide: light dose (70 mg/kg, 2 weeks), medium dose (70 mg/kg, 1 week; 120 mg/kg, 1 week), and high dose (120 mg/kg, 2 weeks). Enzyme-linked immunosorbent assay detected serum levels of sex hormones, and hematoxylin and eosin staining allowed follicle counting and showed the ovarian tissue structure. DiIC 18 (5)-DS was employed to label human amniotic mesenchymal stem cells (hAMSCs) and hAECs for detecting the cellular retention time in ovaries by a live imaging system. Proliferation of human ovarian granule cells (ki67, AMH, FSHR, FOXL2, and CYP19A1) and immunological rejection of human peripheral blood mononuclear cells (CD4, CD11b, CD19, and CD56) were measured by flow cytometry (fluorescence-activated cell sorting (FACS)). Distinction of cellular biological characteristics between hAECs and hAMSCs was evaluated, such as collagen secretory level (collagen I, II, III, IV, and VI), telomerase activity, pluripotent markers tested by western blot, expression level of immune molecules (HLA-ABC and HLA-DR) analyzed by FACS, and cytokines (growth factors, chemotactic factors, apoptosis factors, and inflammatory factors) measured by a protein antibody array methodology. After hAMSCs and hAECs were transplanted into a different degrees of POA model, hAMSCs exerted better therapeutic activity on mouse ovarian function in the high-dose administration group, promoting the proliferation rate of ovarian granular cells from premature ovarian failure patients, but also provoking immune

  15. High rate read-out of LaBr(Ce) scintillator with a fast digitizer

    International Nuclear Information System (INIS)

    Stevanato, L.; Cester, D.; Nebbia, G.; Viesti, G.; Neri, F.; Petrucci, S.; Selmi, S.; Tintori, C

    2012-01-01

    The energy resolution of a LaBr(Ce) detector has been studied as a function of the count rate up to 340 kHz by using a 12 bit 250 MS/s V1720 digitizer. The time resolution achieved by processing off line the digitized signals has been also determined. It appears that the energy resolution obtained with the digitizer is better than that achievable using standard NIM electronics. The time resolution yielded by the digitizer with a software CFTD is about δt=0.8 ns (FWHM), slightly worse with respect to δt=0.65 ns (FWHM) obtained from standard NIM. However, this time resolution lies well within the requirements for applications in Non-Destructive Analysis of large objects with tagged neutron beams.

  16. Human amniotic epithelial cells inhibit CD4+ T cell activation in acute kidney injury patients by influencing the miR-101-c-Rel-IL-2 pathway.

    Science.gov (United States)

    Liu, Junfeng; Hua, Rong; Gong, Zhangbin; Shang, Bin; Huang, Yongyi; Guo, Lihe; Liu, Te; Xue, Jun

    2017-01-01

    In the pathogenesis of acute kidney injury (AKI), the release of multiple interleukins can lead to increased kidney damage. Human amniotic epithelial cells (HuAECs) can inhibit immune cell activation in vivo and in vitro. We hypothesized that HuAECs could weaken patient-derived peripheral blood CD4+ T-cell activation and decreasing the ability of these cells to express and release IL-2. -Cell proliferation assay revealed that under the same culture conditions, activated AKI patient-derived CD4+ T cells had a significantly reduced proliferation rate when were co-cultured with HuAECs. And the level of IL-2 released was also significantly reduced. Western blot and qRT-PCR assays showed that the expression of c-Rel in the CD4+ T cells was also significantly reduced. However, the expression level of endogenous miR-101 in the CD4+ T cells co-cultured with HuAECs was significantly increased. Luciferase reporter assay results suggested that miR-101 could bind to a specific site in the c-Rel 3' UTR and induce the post-transcriptional silencing of c-Rel. Subsequently, we over-expressed miR-101 in AKI patient-derived CD4+ T cells. The qRT-PCR and western blot assay results revealed that the expression of endogenous c-Rel was significantly reduced, while the ELISA results indicated that the level of IL-2 released was also significantly decreased. Finally, ChIP-PCR assay results showed that the miR-101-overexpressing CD4+ T-cell group and the HuAEC co-culture CD4+ T-cell group exhibited significantly decreased binding capacities between the 'c-Rel-NFκB' complex and the IL-2 gene promoter, and the transcriptional activity of IL-2 was also significantly decreased. Therefore, we confirmed that HuAECs can stimulate miR-101 expression in AKI patient-derived peripheral blood CD4+ T cells, thus inhibiting the expression of the miR-101 target gene c-Rel and leading to a reduction in IL-2 expression and release. Copyright © 2016 Elsevier Ltd. All rights reserved.

  17. Muusikamaailm : Hooaja algus "La Scalas". Verdi mälestusaastast mujalgi. Uusooper Ateenasse olümpia-aastaks. Soome ooperi "hullu aasta" lõpp / Priit Kuusk

    Index Scriptorium Estoniae

    Kuusk, Priit, 1938-

    2000-01-01

    Milano La Scala hooaja avaetendustest. G. Verdi ooperite lavastustest New Yorgi, Barcelona, Viini ja Helsingi ooperiteatrites. D. Mitropoulose nim. rahvusvahelisest heliloojate konkursist. K. Tikka uusooperi "Luther" maailmaesiettekandest 12. dets. Helsingi Koopakirikus

  18. Mathematical games, abstract games

    CERN Document Server

    Neto, Joao Pedro

    2013-01-01

    User-friendly, visually appealing collection offers both new and classic strategic board games. Includes abstract games for two and three players and mathematical games such as Nim and games on graphs.

  19. Baletnaja poezija erotiki / Boris Eifman ; interv. Aljona Strizhenova

    Index Scriptorium Estoniae

    Eifman, Boris, 1946-

    2007-01-01

    Lev Tolstoi romaani "Anna Karenina" järgi Boris Eifmani loodud koreograafiaga balletilavastus Pjotr Tšaikovski muusikale. B. Eifmani nim. St-Peterburgi Riikliku Akadeemilise Balletiteatri külalisetendused Tallinnas, 16. juunil

  20. GALILEO NIMS SPECTRAL IMAGE CUBES: JUPITER OPERATIONS

    Data.gov (United States)

    National Aeronautics and Space Administration — The natural form of imaging spectrometer data is the spectral image cube. It is normally in band sequential format, but has a dual nature. It is a series of 'images'...

  1. GALILEO NIMS SPECTRAL IMAGE TUBES: JUPITER OPERATIONS

    Data.gov (United States)

    National Aeronautics and Space Administration — The natural form of imaging spectrometer data is the spectral image cube. It is normally in band sequential format, but has a dual nature. It is a series of 'images'...

  2. BDML Metadata: 189 [SSBD[Archive

    Lifescience Database Archive (English)

    Full Text Available NC-SA 0.180 ed496a82-2baf-4cc3-8fc5-56db2bab7aec 0.105 x 0.105 x 0.5 (micrometer), 40 (second) http://ssbd.q...P002.pdpml0.06.xml http://ssbd.qbic.riken.jp/search/ed496a82-2baf-4cc3-8fc5-56db2bab7aec/ http://ssbd.qbic.riken.jp/omero/webclient/?show=dataset-95 ...

  3. Policy on the decommissioning of nuclear facilities

    International Nuclear Information System (INIS)

    1988-08-01

    This Regulatory Policy Statement describes the policy of the Atomic Energy Control Board (AECB) on the decommissioning of those facilities defined as nuclear facilities in the Atomic Energy Control (AEC) Regulations. It is intended as a formal statement, primarily for the information of licensees, or potential licensees, of the regulatory process and requirements generally applicable to the decommissioning of nuclear facilities licensed and regulated by the AECB pursuant to the authority of the AEC Act and Regulations

  4. Candidate chromosome 1 disease susceptibility genes for Sjogren’s syndrome xerostomia are narrowed by novel NOD.B10 congenic mice

    Science.gov (United States)

    Mongini, Patricia K. A.; Kramer, Jill M.; Ishikawa, Tomo-o; Herschman, Harvey; Esposito, Donna

    2014-01-01

    Sjogren’s syndrome (SS) is characterized by salivary gland leukocytic infiltrates and impaired salivation (xerostomia). Cox-2 (Ptgs2) is located on chromosome 1 within the span of the Aec2 region. In an attempt to demonstrate that COX-2 drives antibody-dependent hyposalivation, NOD.B10 congenic mice bearing a Cox-2flox gene were generated. A congenic line with non-NOD alleles in Cox-2-flanking genes failed manifest xerostomia. Further backcrossing yielded disease-susceptible NOD.B10 Cox-2flox lines; fine genetic mapping determined that critical Aec2 genes lie within a 1.56 to 2.17 Mb span of DNA downstream of Cox-2. Bioinformatics analysis revealed that susceptible and non-susceptible lines exhibit non-synonymous coding SNPs in 8 protein-encoding genes of this region, thereby better delineating candidate Aec2 alleles needed for SS xerostomia. PMID:24685748

  5. Computed tomography of head: impact of the use of automatic exposure control; Doses em tomografia computadorizada de crânio: impacto do uso do controle automático de exposição

    Energy Technology Data Exchange (ETDEWEB)

    Souza, Giordana Salvi de Souza; Froner, Ana Paula Pastre; Silva, Ana Maria Marques da, E-mail: giordana.souza@acad.pucrs.br [Pontificia Universidade catolica do Rio Grande do Sul (PUC-RS), Porto Alegre, RS (Brazil). Núcleo de Pesquisa em Imagens Médicas

    2017-07-01

    The use of dose reduction systems in computed tomography is particularly important for pediatric patients, who have a high radiosensitivity, since they are in the growing phase. The aim of this study was to evaluate the impact of Siemens AEC Care Dose system use on dose estimation in head computed tomography scans in pediatric patients. A retrospective study was conducted with 199 computed tomography head scans of pediatric patients, divided in different age groups, on a 16-channel Siemens Emotion scanner. It was possible to observe, for all age groups, that the use of AEC Care Dose system, not only reduced CTDI{sub vol}, but also the interquartile range, reducing the total dose in the investigated population. Concluding, AEC Care Dose system models the tube current according to the patient's dimensions, reducing individual and collective dose without affecting the diagnostic quality . (author)

  6. Safety analysis and review system: a Department of Energy safety assurance tool

    International Nuclear Information System (INIS)

    Rosenthal, H.B.

    1981-01-01

    The concept of the Safety Analysis and Review System is not new. It has been used within the Department and its predecessor agencies, Atomic Energy Commission (AEC) and Energy Research and Development Administration (ERDA), for over 20 years. To minimize the risks from nuclear reactor and power plants, the AEC developed a process to support management authorization of each operation through identification and analysis of potential hazards and the measures taken to control them. As the agency evolved from AEC through ERDA to the Department of Energy, its responsibilities were broadened to cover a diversity of technologies, including those associated with the development of fossil, solar, and geothermal energy. Because the safety analysis process had proved effective in a technology of high potential hazard, the Department investigated the applicability of the process to the other technologies. This paper describes the system and discusses how it is implemented within the Department

  7. La influencia social de los medios de comunicación en Twitter

    Directory of Open Access Journals (Sweden)

    Karines Rodríguez Díaz

    2017-06-01

    Full Text Available En este artículo se expone cómo se desarrolla la influencia social de los medios de comunicación sobre los usuarios en Twitter, durante la celebración de la VII Cumbre de la Asociación de Estados del Caribe (AEC. La investigación parte del análisis de un corpus de 1500 tuits con las etiquetas temáticas #CubaCaribe, #VIICumbreAEC, #CumbreAEC. Utilizando el análisis del discurso mediado por computador, los resultados muestran la habilidad de influencia de los medios de comunicación a través de patrones de repetición-reacción y en la construcción del consenso sobre la valoración del acontecimiento. El reporte de caso explica cómo los parlamentos mediáticos repercuten en la comunidad de usuarios en el contexto microblogging.

  8. [Investigation of radiation dose for lower tube voltage CT using automatic exposure control].

    Science.gov (United States)

    Takata, Mitsuo; Matsubara, Kousuke; Koshida, Kichirou; Tarohda, Tohru

    2015-04-01

    The purpose of our study was to investigate radiation dose for lower tube voltage CT using automatic exposure control (AEC). An acrylic body phantom was used, and volume CT dose indices (CTDIvol) for tube voltages of 80, 100, 120, and 135 kV were investigated with combination of AEC. Average absorbed dose in the abdomen for 100 and 120 kV were also measured using thermoluminescence dosimeters. In addition, we examined noise characteristics under the same absorbed doses. As a result, the exposure dose was not decreased even when the tube voltage was lowered, and the organ absorbed dose value became approximately 30% high. And the noise was increased under the radiographic condition to be an equal absorbed dose. Therefore, radiation dose increases when AEC is used for lower tube voltage CT under the same standard deviation (SD) setting with 120 kV, and the optimization of SD setting is crucial.

  9. A Method for the Automatic Exposure Control in Pediatric Abdominal CT: Application to the Standard Deviation Value and Tube Current Methods by Using Patient's Age and Body Size.

    Science.gov (United States)

    Furuya, Ken; Akiyama, Shinji; Nambu, Atushi; Suzuki, Yutaka; Hasebe, Yuusuke

    2017-01-01

    We aimed to apply the pediatric abdominal CT protocol of Donnelly et al. in the United States to the pediatric abdominal CT-AEC. Examining CT images of 100 children, we found that the sectional area of the hepatic portal region (y) was strongly correlated with the body weight (x) as follows: y=7.14x + 84.39 (correlation coefficient=0.9574). We scanned an elliptical cone phantom that simulates the human body using a pediatric abdominal CT scanning method of Donnelly et al. in, and measured SD values. We further scanned the same phantom under the settings for adult CT-AEC scan and obtained the relationship between the sectional areas (y) and the SD values. Using these results, we obtained the following preset noise factors for CT-AEC at each body weight range: 6.90 at 4.5-8.9 kg, 8.40 at 9.0-17.9 kg, 8.68 at 18.0-26.9 kg, 9.89 at 27.0-35.9 kg, 12.22 at 36.0-45.0 kg, 13.52 at 45.1-70.0 kg, 15.29 at more than 70 kg. From the relation between age, weight and the distance of liver and tuber ischiadicum of 500 children, we obtained the CTDI vol values and DLP values under the scanning protocol of Donnelly et al. Almost all of DRL from these values turned out to be smaller than the DRL data of IAEA and various countries. Thus, by setting the maximum current values of CT-AEC to be the Donnelly et al.'s age-wise current values, and using our weight-wise noise factors, we think we can perform pediatric abdominal CT-AEC scans that are consistent with the same radiation safety and the image quality as those proposed by Donnelly et al.

  10. SU-E-I-68: Practical Considerations On Implementation of the Image Gently Pediatric CT Protocols

    International Nuclear Information System (INIS)

    Zhang, J; Adams, C; Lumby, C; Dillon, J; Woods, E; Richer, E

    2014-01-01

    Purpose: One limitation associated with the Image Gently pediatric CT protocols is practical implementation of the recommended manual techniques. Inconsistency as a result of different practice is a possibility among technologist. An additional concern is the added risk of data error that would result in over or underexposure. The Automatic Exposure Control (AEC) features automatically reduce radiation for children. However, they do not work efficiently for the patients of very small size and relative large size. This study aims to implement the Image Gently pediatric CT protocols in the practical setting while maintaining the use of AEC features for pediatric patients of varying size. Methods: Anthropomorphological abdomen phantoms were scanned in a CT scanner using the Image Gently pediatric protocols, the AEC technique with a fixed adult baseline, and automatic protocols with various baselines. The baselines were adjusted corresponding to patient age, weight and posterioranterior thickness to match the Image Gently pediatric CT manual techniques. CTDIvol was recorded for each examination. Image noise was measured and recorded for image quality comparison. Clinical images were evaluated by pediatric radiologists. Results: By adjusting vendor default baselines used in the automatic techniques, radiation dose and image quality can match those of the Image Gently manual techniques. In practice, this can be achieved by dividing pediatric patients into three major groups for technologist reference: infant, small child, and large child. Further division can be done but will increase the number of CT protocols. For each group, AEC can efficiently adjust acquisition techniques for children. This implementation significantly overcomes the limitation of the Image Gently manual techniques. Conclusion: Considering the effectiveness in clinical practice, Image Gently Pediatric CT protocols can be implemented in accordance with AEC techniques, with adjusted baselines, to

  11. Prognostics of damage accural in SSL luminaires and drivers subjected to HTSL accelerated aging

    Energy Technology Data Exchange (ETDEWEB)

    Lall, Pradeep [Auburn Univ., AL (United States); Sakalaukus, Peter [Auburn Univ., AL (United States); Davis, Lynn [RTI International, Research Triangle Park, NC (United States)

    2013-07-16

    This paper will show an investigation of off-the-shelf luminaires with the focus on the LED electronic drivers, specifically the aluminum electrolytic capacitors (AECs), that have been aged using high temperature shelf life (HTSL) testing of 135°C in order to prognosticate the remaining useful life of the luminaires. Luminaires have the potential of seeing excessive temperatures when being transported across country or being stored in non-climate controlled warehouses. They are also being used in outdoor applications in desert environments that see little or no humidity but will experience extremely high temperatures during the day. This makes it important to increase our understanding of what effects being stored at high temperatures for a prolonged period of time will have on the usability and survivability of these devices. The U.S. Department of Energy has made a long term commitment to advance the efficiency, understanding and development of solid-state lighting (SSL) and is making a strong push for the acceptance and use of SSL products. In this work, the four AECs of three different types inside each LED electronic driver were studied. The change in capacitance and the change in equivalent series resistance (ESR) of the AECs were measured and considered to be a leading indication of failure of the LED system. These indicators were used to make remaining useful life predictions to develop an algorithm to predict the end of life of the AECs. The luminous flux of a pristine downlight module was also monitored using each LED electronic driver that was subjected to HTSL through the progression of the testing to determine a correlation between the light output of the lamp and the failing components of the LED electronic driver. Prognostic and Health Management (PHM) is a useful tool for assessment of the remaining life of electrical components and is demonstrated for AECs in this work.

  12. IMPLEMENTASI HKI PADA PRODUK UNGGULAN IKM SEKTOR MAKANAN DI KOTA MADIUN UNTUK BERSAING DALAM MASYARAKAT EKONOMI ASEAN

    Directory of Open Access Journals (Sweden)

    Farida Styaningrum

    2017-11-01

    Full Text Available Intellectual Property Rights (IPRs on excellent product of Small and Medium Industry (SMI food sector in Madiun can encourage business development and provide a competitive advantage when entering in ASEAN or AEC free trade. This research aims to determine the implementation of IPRs by Industry Sector, Department of Manpower of Madiun on excellent product of SMI food sector, perception of SMI food sector perpetrator to IPRs, and obstacles faced in the implementation of IPRs on excellent product of food sector in Madiun to compete in AEC. The approach method used is qualitative descriptive. The results showed that the Industry Sector, Manpower Office of Madiun in implementing IPRs on excellent product of SMI food sector in Madiun to compete in AEC less effectively. SMI in the food sector in Madiun assume that IPRs is not so important to compete in the MEA. The obstacles faced in the implementation of IPRs on excellent product of SMI food sector in Madiun to compete in AEC: SMI data of incomplete food sector, limited number of SMI food sector in registration of IPRs, socialization of IPRs less effective, lack of understanding of perpetrator SMI on IPRs, and the lack of appreciation of SME actors against IPRs, lack of understanding of SMI actors concerning IPR, and lack of appreciation of SME actors against IPR

  13. Trends and Opportunities of BIM-GIS Integration in the Architecture, Engineering and Construction Industry: A Review from a Spatio-Temporal Statistical Perspective

    Directory of Open Access Journals (Sweden)

    Yongze Song

    2017-12-01

    Full Text Available The integration of building information modelling (BIM and geographic information system (GIS in construction management is a new and fast developing trend in recent years, from research to industrial practice. BIM has advantages on rich geometric and semantic information through the building life cycle, while GIS is a broad field covering geovisualization-based decision making and geospatial modelling. However, most current studies of BIM-GIS integration focus on the integration techniques but lack theories and methods for further data analysis and mathematic modelling. This paper reviews the applications and discusses future trends of BIM-GIS integration in the architecture, engineering and construction (AEC industry based on the studies of 96 high-quality research articles from a spatio-temporal statistical perspective. The analysis of these applications helps reveal the evolution progress of BIM-GIS integration. Results show that the utilization of BIM-GIS integration in the AEC industry requires systematic theories beyond integration technologies and deep applications of mathematical modeling methods, including spatio-temporal statistical modeling in GIS and 4D/nD BIM simulation and management. Opportunities of BIM-GIS integration are outlined as three hypotheses in the AEC industry for future research on the in-depth integration of BIM and GIS. BIM-GIS integration hypotheses enable more comprehensive applications through the life cycle of AEC projects.

  14. Excess of Radiation Burden for Young Testicular Cancer Patients using Automatic Exposure Control and Contrast Agent on Whole-body Computed Tomography Imaging.

    Science.gov (United States)

    Niiniviita, Hannele; Kulmala, Jarmo; Pölönen, Tuukka; Määttänen, Heli; Järvinen, Hannu; Salminen, Eeva

    2017-06-01

    The aim of the study was to assess patient dose from whole-body computed tomography (CT) in association with patient size, automatic exposure control (AEC) and intravenous (IV) contrast agent. Sixty-five testicular cancer patients (mean age 28 years) underwent altogether 279 whole-body CT scans from April 2000 to April 2011. The mean number of repeated examinations was 4.3. The GE LightSpeed 16 equipped with AEC and the Siemens Plus 4 CT scanners were used for imaging. Whole-body scans were performed with (216) and without (63) IV contrast. The ImPACT software was used to determine the effective and organ doses. Patient doses were independent (p < 0.41) of patient size when the Plus 4 device (mean 7.4 mSv, SD 1.7 mSv) was used, but with the LightSpeed 16 AEC device, the dose (mean 14 mSv, SD 4.6 mSv) increased significantly (p < 0.001) with waist cirfumference. Imaging with the IV contrast agent caused significantly higher (13% Plus 4, 35% LightSpeed 16) exposure than non-contrast imaging (p < 0.001). Great caution on the use of IV contrast agent and careful set-up of the AEC modulation parameters is recommended to avoid excessive radiation exposure on the whole-body CT imaging of young patients.

  15. Literary awards 2002 / Piret Viires

    Index Scriptorium Estoniae

    Viires, Piret, 1963-

    2003-01-01

    Riigi kultuuripreemia - Hando Runnel (elutööpreemia) ; Balti Assamblee kirjandusauhind - Jaan Tätte ("Sild" ja "Palju õnne argipäevaks") ; A. H. Tammsaare nim. romaaniauhind - Andrus Kivirähk ("Rehepapp") ; Eesti Kultuurkapitali aastapreemia - Aleksander Suuman ("Tondihobu tõugud vetikatega") ; Kultuurkapitali kirjanduse aastapreemiad: proosa - Jüri Ehlvest ("Hobune eikusagilt"), luule - Karl Martin Sinijärv ("Artutart & 39"), esseistika - Peeter Mudist ("Ratsukäik"), näitekirjandus - Vaino Vahing ("Mängud ja kõnelused"), lastekirjandus - Heino Kiik ("Kuresaapad"), tõlge eesti keelde - Mati Sirkel (Franz Kafka "Hiina müüri ehitamisel" tõlge), tõlge eesti keelest - Antoine Chalvin (Jaan Kaplinski "Le désir de la pousicre" tõlge), artiklipreemia - Tõnu Õnnepalu ("Kui... Küpsemine. Aleksander Suumani kaks luuletust ja üks raamat ("Meil siin Hüperboreas")", ilmus Loomingus, nr. 5-6), venekeelsete autorite kirjandusauhind - Mihhail Veller (viimase 10 aasta proosaloomingu eest) ; B. Alveri kirjandusauhind - Leo Kunnas ("Sõdurjumala teener") ja Ülar Ploom ("Üks ja kogu"); 2002. a. romaanivõistluse võitja - Nikolai Baturin ("Kentaur") ; A. H. Tammsaare nim. kirjanduspreemia - Elem Treier ("Tammsaare elu härra Hansenina") ; E. Vilde nim. kirjandusauhind - Doris Kareva ("Mandragora") ; F. Tuglase novelliauhind - Jüri Ehlvest ("Hobune eikusagilt", Looming, 2002, nr. 1) ja Jaan Undusk ("Armastus raamatu vastu", ilmus kogumikus "Puudutus"); Juhan Liivi luuleauhind - Andres Ehin (luuletus "sügaval maa all elavad...", Looming, 2002, nr. 4)

  16. Development and validation of a novel RP-HPLC method for simultaneous determination of paracetamol, phenylephrine hydrochloride, caffeine, cetirizine and nimesulide in tablet formulation

    Directory of Open Access Journals (Sweden)

    A.P. Dewani

    2015-07-01

    Full Text Available The present work describes development and validation of a high-performance liquid chromatography–diode array detection (HPLC–DAD procedure for the analysis of phenylephrine hydrochloride (PHE, paracetamol (PAR, caffeine anhydrous (CAF, cetirizine Dihydrochloride (CET, nimesulide (NIM in pharmaceutical mixture. Effective chromatographic separation of PHE, PAR, CAF, CET and NIM was achieved using a Kinetex-C18 (4.6 mm, 150 mm, 5 mm column with gradient elution of the mobile phase composed of 10 mM phosphate buffer (pH 3.3 and acetonitrile. The elution was a three step gradient elution program step-1 started initially with 2% (by volume acetonitrile and 98% phosphate buffer (pH 3.3 for first 2 min. In step-2 acetonitrile concentration changed linearly to 20% up to 12 min the analysis was concluded by step-3 changing acetonitrile to 2% up to 20 min. The proposed HPLC method was statistically validated with respect to linearity, ranges, precision, accuracy, selectivity and robustness. Calibration curves were linear in the ranges of 5–100, 100–1000 and 10–200 mg/mL for PHE, PAR, CAF, CET and NIM respectively, with correlation coefficients >0.9996. The HPLC method was applied to tablet dosage form in which the analytes were successfully quantified with good recovery values with no interfering peaks from the excipients.

  17. V prostranstve mezhdu soboi i personazhem / Stella Saltõkova

    Index Scriptorium Estoniae

    Saltõkova, Stella

    2006-01-01

    16. juunil. andis Tallinnas Vene Kultuurikeskuses külalisetendusi Georgi Tovstonogovi nim. Suur Draamateater. Mängiti Ronald Harwoodi "Kvartetti", osalesid vene näitlejad Alissa Freindlihh, Kirill Lavrov, Oleg Basilashvili ja Zinaida Sharko

  18. Tallinn ja Peterburi : kultuurikontaktid / Ester Shank

    Index Scriptorium Estoniae

    Šank, Ester, 1956-

    2007-01-01

    Tallinna volikogu esinduse kohtumisest Peterburi kolleegidega, ka kontserdist Georg Otsa mälestuseks 8. nov. Peterburi endise Väikese Ooperi- ja Balletiteatri, nüüd Mihhailovski-nim. teatri saalis (õhtujuhiks Arne Mikk)

  19. Картошку на премию покупать не собираюсь / Андрус Кивиряхк ; интервьюировал Ивар Сильд

    Index Scriptorium Estoniae

    Кивиряхк, Андрус, 1970-

    2003-01-01

    A. Kivirähk pälvis A. H. Tammsaare nim. romaaniauhinna "Rehepapi" eest. Intervjuu on ilmunud SL Õhtulehes pealk. "Sherlock Holmes tegi ka vahepeal keemiakatseid". Tõlkija on intervjuud lühendanud

  20. Location of radiosensitive organs, measurement of absorbed dose to radiosensitive organs and use of bismuth shields in paediatric anthropomorphic phantoms

    International Nuclear Information System (INIS)

    Inkoom, S.

    2014-08-01

    The aim of this study was to investigate: firstly, (i) location of radiosensitive organs in the interior of four (4) paediatric anthropomorphic phantoms, and, secondly, (ii) effectiveness of single and double bismuth thyroid shields, distance between shield and phantom surface, during paediatric multi-detector computed tomography (MDCT) using fixed tube current (FTC) and automatic exposure control (AEC) on dose reduction and image quality. Four (4) paediatric anthropomorphic phantoms representing the equivalent of a newborn, 1-, 5-, and 10-y-old child underwent head, thorax and abdomen computed tomography (CT) scans. CT and magnetic resonance imaging scans of all children aged 0-16 y-old performed during a 5-y-period at the University Hospital of Heraklion, Crete, Greece were reviewed, and five hundred and three (503) were found to be eligible for normal anatomy. Anterior-posterior and lateral dimensions of twelve (12) of the above children closely matched that of the phantoms' thoracic and abdominal region in each four (4) phantoms. The mid-sagittal plane (MSP) and mid-coronal plane (MCP) were drawn on selected matching axial images of patients and phantoms. Multiple points outlining large radiosensitive organs and centres of small organs in patient images were identified at each slice level and their orthogonal distances from the MSP and MCP were measured. The outlines and centres of all radiosensitive organs were reproduced using the coordinates of each organ on the corresponding phantom's transverse images. The four (4) phantoms were also subjected to routine head and neck, neck and thorax CT scans on a 16-slice CT system. Each phantom was first scanned with both FTC and AEC for with and without bismuth shields. Each scan was repeated ten (10) times to increase thermoluminescent dosimeters (TLDs) signal and reduce measurement statistical error. For neck CT, the effect of using single and double thickness of bismuth shields and 1-3 cm cotton spacers

  1. Kiviõlis kõlavad "West Side Story" laulud / Inna Grünfeldt

    Index Scriptorium Estoniae

    Grünfeldt, Inna, 1961-

    2004-01-01

    Tallinna Georg Otsa nim. Muusikakooli viiepäevasest treeninglaagrist Kiviõli Keemiatööstuse hoones ja kontserdist muusikali "West Side Story" lauludega 27. aug. (ettevalmistus 4. sept. Tallinnas esietenduvale muusikalile, projektijuht Eerika Kurm)

  2. Muusikamaailm : Wien Modern 2000. Muusikateater Huddersfieldis. Sibeliuse konkurss Helsingis. Penderecki uus teos Tokyos / Priit Kuusk

    Index Scriptorium Estoniae

    Kuusk, Priit, 1938-

    2000-01-01

    Nüüdismuusikafestivalist "Wien Modern" 28. okt.-26. nov. Muusikalavastustest Huddersfieldi kaasaegse muusika festivalil. VIII Sibeliuse nim. rahvusvahelisest viiuldajate konkursist. 30. nov. toimus Tokyos K. Penderecki teose "Concerto grosso per tre violoncelli ed orchestra"

  3. Parts lubas uut muusikakooli

    Index Scriptorium Estoniae

    2005-01-01

    Peaminister Juhan Parts vastas Tallinna Muusikakeskkooli õpilase Judith Partsi kirjale Tallinna Muusikakeskkooli olukorrast lubadusega hoida silma peal Tallinna Muusikakeskkoolile, Tallinna Balletikoolile ja Georg Otsa nim. Muusikakoolile ühise hoone võimaldamisest kokkuehituseks Eesti Muusikaakadeemiaga

  4. Monte Carlo Simulation of Callisto's Exosphere

    Science.gov (United States)

    Vorburger, Audrey; Wurz, Peter; Galli, André; Mousis, Olivier; Barabash, Stas; Lammer, Helmut

    2014-05-01

    Whereas Callisto's surface has been mapped as early as in 1980 by the two Voyager missions, Callisto's tenuous atmosphere, also called an exosphere, was not directly observed until the Galileo mission in 1999. The Galileo Near-Infrared Mapping Spectrometer detected a CO2 signal up to 100 km above the surface [Carlson, Science, 1999]. Radio occultation measurements, also conducted by Galileo, led to the detection of an ionosphere with inferred densities much higher than can be explained by the measured CO2 exosphere, though [Kliore et al., J. Geophys. Res, 2002]. Insight about Callisto's exosphere is expected to be boosted by the Neutral Ion Mass Spectrometer (NIM) of the Particle Environment Package (PEP) on board the planned JUpiter ICy moons Explorer (JUICE) mission, which will conduct the first-ever direct sampling of the exospheres of Europa, Ganymede, and Callisto. To ensure that NIM's mass resolution and mass range will be sufficient for NIM to detect most expected species in Callisto's exosphere, we model said exosphere ab initio. Since Callisto is thought to consist to about equal parts of both icy and rocky components [Showman and Malhotra, Science, 1999], we model particle release from an icy as well as from a mineral surface separately. For the ice component, we investigate two different compositions, for reducing and oxidising conditions, which find analogy in the initial gas phase conditions in the solar nebula [Mousis et al., Planet. Space Sci., submitted]. For the non-ice material, the mineral surface, we investigate surfaces with compositions similar to CI chondrites and L/LL type chondrites, both of which have been suggested to represent Callisto's non-ice material best [Kuskov and Kronrod, Icarus, 2005 and Moore et al., Cambridge University Press, 2004]. For all mentioned materials, we compute density profiles for particles released by either surface sublimation or ion induced sputtering up to an altitude of 100'000 km. Our results show that close

  5. Surgical management of acute cholecystitis. Results of a nation-wide survey among Spanish surgeons.

    Science.gov (United States)

    Badia, Josep M; Nve, Esther; Jimeno, Jaime; Guirao, Xavier; Figueras, Joan; Arias-Díaz, Javier

    2014-10-01

    There is a wide variability in the management of acute cholecystitis. A survey among the members of the Spanish Association of Surgeons (AEC) analyzed the preferences of Spanish surgeons for its surgical management. The majority of the 771 responders didn't declare any subspecialty (41.6%), 21% were HPB surgeons, followed by colorectal and upper-GI specialities. Early cholecystectomy during the first admission is the preferred method of management of 92.3% of surgeons, but only 42.7% succeed in adopting this practice. The most frequent reasons for changing their preferred practice were: Patients not fit for surgery (43.6%) and lack of availability of emergency operating room (35.2%). A total of 88.9% perform surgery laparoscopically. The majority of AEC surgeons advise index admission cholecystectomy for acute cholecystitis, although only half of them succeed in its actual implementation. There is room for improvement in the management of acute cholecystitis in Spanish hospitals. Copyright © 2013 AEC. Published by Elsevier Espana. All rights reserved.

  6. Ultrahigh-rate supercapacitors based on eletrochemically reduced graphene oxide for ac line-filtering

    Science.gov (United States)

    Sheng, Kaixuan; Sun, Yiqing; Li, Chun; Yuan, Wenjing; Shi, Gaoquan

    2012-02-01

    The recent boom in multifunction portable electronic equipments requires the development of compact and miniaturized electronic circuits with high efficiencies, low costs and long lasting time. For the operation of most line-powered electronics, alternating current (ac) line-filters are used to attenuate the leftover ac ripples on direct current (dc) voltage busses. Today, aluminum electrolytic capacitors (AECs) are widely applied for this purpose. However, they are usually the largest components in electronic circuits. Replacing AECs by more compact capacitors will have an immense impact on future electronic devices. Here, we report a double-layer capacitor based on three-dimensional (3D) interpenetrating graphene electrodes fabricated by electrochemical reduction of graphene oxide (ErGO-DLC). At 120-hertz, the ErGO-DLC exhibited a phase angle of -84 degrees, a specific capacitance of 283 microfaradays per centimeter square and a resistor-capacitor (RC) time constant of 1.35 milliseconds, making it capable of replacing AECs for the application of 120-hertz filtering.

  7. Rulison Site groundwater monitoring report fourth quarter, 1996. Revision 4

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-04-01

    Project Rulison, a joint US Atomic Energy Commission (AEC) and Austral Oil Company (Austral) experiment, was conducted under the AEC`s Plowshare Program to evaluate the feasibility of using a nuclear device to stimulate natural gas production in low-permeability, gas-producing geologic formations. The experiment was conducted on September 10, 1969, and consisted of detonating a 40-kiloton nuclear device at a depth of 2,568 m below ground surface. This report summarizes the results of the fourth quarter 1996 groundwater sampling event for the Rulison Site, which is located approximately 65 kilometers (km) (40 miles [mi]) northeast of Grand Junction, Colorado. The sampling was performed as part of a quarterly groundwater monitoring program implemented by the US Department of Energy (DOE) to monitor the effectiveness of remediation of a drilling effluent pond located at the site. The effluent pond was used for the storage of drilling mud during drilling of the emplacement hole for a 1969 gas stimulation test.

  8. Atoms for peace and war, 1953-1961

    International Nuclear Information System (INIS)

    Hewlett, R.G.; Holl, J.M.

    1989-01-01

    This is the third book in a series by the author dealing with the Atomic Energy Commission (AEC). The material ranges from debates over how to use nuclear power to generate electricity to the development of the deadliest weapons in human history. Also included are a concise account of the Oppenheimer affair, a clear history of Eisenhower's Atoms for Peace initiative, and a balanced report of the partisan battle over the development of nuclear power, with Democrats insisting on a major role for government while the Republicans championed a free enterprise approach. The nearly 600 pages of text are organized around three central themes: (1) the close connection between the two seemingly different concerns of the AEC - atoms for peace and atoms for war; (2) the conflict of interest the AEC faced over the issue of nuclear testing; and (3) the central role played by Dwight D. Eisenhower in shaping American nuclear policy in the 1950s

  9. Endogenous Murine BST-2/Tetherin Is Not a Major Restriction Factor of Influenza A Virus Infection.

    Directory of Open Access Journals (Sweden)

    Sarah L Londrigan

    Full Text Available BST-2 (tetherin, CD317, HM1.24 restricts virus growth by tethering enveloped viruses to the cell surface. The role of BST-2 during influenza A virus infection (IAV is controversial. Here, we assessed the capacity of endogenous BST-2 to restrict IAV in primary murine cells. IAV infection increased BST-2 surface expression by primary macrophages, but not alveolar epithelial cells (AEC. BST-2-deficient AEC and macrophages displayed no difference in susceptibility to IAV infection relative to wild type cells. Furthermore, BST-2 played little role in infectious IAV release from either AEC or macrophages. To examine BST-2 during IAV infection in vivo, we infected BST-2-deficient mice. No difference in weight loss or in viral loads in the lungs and/or nasal tissues were detected between BST-2-deficient and wild type animals. This study rules out a major role for endogenous BST-2 in modulating IAV in the mouse model of infection.

  10. Real-time adaptive concepts in acoustics blind signal separation and multichannel echo cancellation

    CERN Document Server

    Schobben, Daniel W E

    2001-01-01

    Blind Signal Separation (BSS) deals with recovering (filtered versions of) source signals from an observed mixture thereof. The term `blind' relates to the fact that there are no reference signals for the source signals and also that the mixing system is unknown. This book presents a new method for blind signal separation, which is developed to work on microphone signals. Acoustic Echo Cancellation (AEC) is a well-known technique to suppress the echo that a microphone picks up from a loudspeaker in the same room. Such acoustic feedback occurs for example in hands-free telephony and can lead to a perceived loud tone. For an application such as a voice-controlled television, a stereo AEC is required to suppress the contribution of the stereo loudspeaker setup. A generalized AEC is presented that is suited for multi-channel operation. New algorithms for Blind Signal Separation and multi-channel Acoustic Echo Cancellation are presented. A background is given in array signal processing methods, adaptive filter the...

  11. Report on Greece. Establishment of an atomic centre

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1959-07-15

    An IAEA mission was informed of the present and planned activities of the Greek AEC at the Democritus Nuclear Centre and outside this Centre, in particular at the Alexandra Hospital in Athens. Created in 1954, the Greek AEC deals with all atomic energy matters in the country, including research, education, safety, isotope applications and prospecting. The main project of the Commission is the establishment of the Democritus Nuclear Centre, which will have a research reactor and a number of supplementary laboratories. Following an agreement with the US Government, a site has been chosen for the Centre on the outskirts of Athens. The reactor will be of the swimming pool type, with a maximum thermal output of 1 mw. The construction of the reactor building is being carried out under the responsibility of the Greek AEC. The laboratories at the Nuclear Centre will consist of buildings for physics, chemistry, technology, biology, a hot laboratory and a decontamination unit. At the time of the mission's visit, the reactor building and a temporary laboratory were under construction. A certain amount of atomic energy research is also carried out at the Physics Institute of the University of Athens. Since 1956, a radioisotope laboratory has been in operation at the Department of Clinical Therapeutics of Athens University; the laboratory is located at the Alexandra Hospital. The members of the IAEA mission discussed the country's needs of technical assistance with the members of the Greek AEC and with its scientific staff. The AEC wishes to ensure the effective execution of their projects for the setting up of a nuclear research centre and for the development of a sound and balanced research programme, as well as for the establishment of adequate health and safety measures in work with ionizing radiations throughout the country. It is also intended to promote the use of radioisotopes in medicine, which is already being done at the Alexandra Hospital. The Greek AEC requested

  12. Report on Greece. Establishment of an atomic centre

    International Nuclear Information System (INIS)

    1959-01-01

    An IAEA mission was informed of the present and planned activities of the Greek AEC at the Democritus Nuclear Centre and outside this Centre, in particular at the Alexandra Hospital in Athens. Created in 1954, the Greek AEC deals with all atomic energy matters in the country, including research, education, safety, isotope applications and prospecting. The main project of the Commission is the establishment of the Democritus Nuclear Centre, which will have a research reactor and a number of supplementary laboratories. Following an agreement with the US Government, a site has been chosen for the Centre on the outskirts of Athens. The reactor will be of the swimming pool type, with a maximum thermal output of 1 mw. The construction of the reactor building is being carried out under the responsibility of the Greek AEC. The laboratories at the Nuclear Centre will consist of buildings for physics, chemistry, technology, biology, a hot laboratory and a decontamination unit. At the time of the mission's visit, the reactor building and a temporary laboratory were under construction. A certain amount of atomic energy research is also carried out at the Physics Institute of the University of Athens. Since 1956, a radioisotope laboratory has been in operation at the Department of Clinical Therapeutics of Athens University; the laboratory is located at the Alexandra Hospital. The members of the IAEA mission discussed the country's needs of technical assistance with the members of the Greek AEC and with its scientific staff. The AEC wishes to ensure the effective execution of their projects for the setting up of a nuclear research centre and for the development of a sound and balanced research programme, as well as for the establishment of adequate health and safety measures in work with ionizing radiations throughout the country. It is also intended to promote the use of radioisotopes in medicine, which is already being done at the Alexandra Hospital. The Greek AEC requested

  13. Annual changes in abundance of non-indigenous marine benthos on a very large spatial scale

    DEFF Research Database (Denmark)

    Thomsen, Mads S.; Wernberg, Thomas; Stæhr, Peter Anton

    2008-01-01

    to quantify annual nation-wide changes in abundance of non-indigenous soft-bottom invertebrates (from grab samples) and hard-bottom macroalgae (from diver based percent cover values) in Denmark. Based on criteria of being either abundant (constituting >1% of the entire Danish assemblages) or increasing...... in abundance, NIMS of particular interest were found to be Mya arenaria and Bonemaissonia hamifera (abundant), Crepidula fornicata, Ensis americanus, Neanthes succinea (a cryptogenic species), Marenzelleria spp. (increasing), and Sargassum muticum (abundant and increasing). In addition, new and/or warm......-water eurohaline NIMS such as Gracilaria vermiculophylla and Crassostrea gigas, should be given attention as these species are expected to increase in the future. Finally, species not included in existing monitoring programs (hard-bottom estuarine invertebrates, fish, parasites, highly mobile species) should also...

  14. PENGARUH MANAJEMEN ASET, MANAJEMEN LIABILITI, MANAJEMEN ASET LIABILITI TERHADAP ECONOMIC VALUE ADDED (EVA PADA PERBANKAN KONVENSIONAL YANG TERDAFTAR DI BURSA EFEK INDONESIA

    Directory of Open Access Journals (Sweden)

    H Hamidah

    2013-08-01

    Full Text Available Generally, company wants to optimize its profit. Properly manage the asset management, liability management and asset liability management can provide value added profits for the company. A sample of research consists of 18 banking companies listed at Indonesia Stock Exchange (IDX during the 2005-2009. This research investigate the relationship net loans/total earning assets (NLA, non performing loan (NPL, liabilities/total assets (LA, equity/total assets (EA, net interest margin (NIM, loan to deposite ratio (LDR on economic value added (EVA. The research use regression of panel data. The result show that net loans/total earning assets (NLA, liabilities/total assets (LA, equity/total assets (EA, net interest margin (NIM, loan to deposite ratio (LDR are have significant effect on economic value added (EVA but non performing loan (NPL.

  15. PENGARUH KARAKTERISTIK DEWAN DIREKSI TERHADAP PENGUKURAN KINERJA BANK DI INDONESIA

    Directory of Open Access Journals (Sweden)

    Susy Muchtar

    2009-09-01

    Full Text Available The purpose of this research is to analyse the effect of Characteristics of The Board of towar Directors s Bank Performance. This research was used are 19 banking firm which listed in Indonesian Stock Exchange during 2005-2008. Independent variables from this research are board size and Outside Director. Dependent variables are bank performance which include Net Interest Margin (NIM, Return On Asset (ROA, Return On Equity(ROE and Efficiency Ratio. Control Variables are Size, Risk and Capital Ratio. The analysis method was used are multiple regression analysis. The result from this research shows that Board Size did not has related to bank performance. Outsiders has related to bank performance. Keywords: Board Size, Outside Director, Net Interest Margin (NIM, Return On Asset (ROA, Return On Equity(ROE and Efficiency Ratio

  16. Creating double negative index materials using the Babinet principle with one metasurface

    Science.gov (United States)

    Zhang, Lei; Koschny, Thomas; Soukoulis, C. M.

    2013-01-01

    Metamaterials are patterned metallic structures which permit access to a novel electromagnetic response, negative index of refraction, impossible to achieve with naturally occurring materials. Using the Babinet principle, the complementary split ring resonator (SRR) is etched in a metallic plate to provide negative ɛ, with perpendicular direction. Here we propose a new design, etched in a metallic plate to provide negative magnetic permeability μ, with perpendicular direction. The combined electromagnetic response of this planar metamaterial, where the negative μ comes from the aperture and the negative ɛ from the remainder of the continuous metallic plate, allows achievement of a double negative index metamaterial (NIM) with only one metasurface and strong transmission. These designs can be used to fabricate NIMs at microwave and optical wavelengths and three-dimensional metamaterials.

  17. Ruzhjo dolzhno võstrelit / Boris Tuch

    Index Scriptorium Estoniae

    Tuch, Boris, 1946-

    2005-01-01

    Mängufilm "Libahundi needus" : stsenaristid Margus Kasterpalu, Ilmar Raag ja Rainer Sarnet : režissöör Rainer Sarnet : Shop of Dreams - Eesti Televisioon 2005. Ka "teatrineedusest" Moskva Pushkini nim. teatri näitel

  18. Uudised : Ernesaksa auhind ning stipendiumid. Arvo Pärdi uus teos Roomas. Paavo Järvi Euroopas / Ilmar Moss

    Index Scriptorium Estoniae

    Moss, Ilmar

    2000-01-01

    4. dets. toimus Kuusalus G.Ernesaksa mälestuskontsert, kus anti üle stipendiumid ja Ernesaksa nim. auhind. 19. nov. toimus Roomas A.Pärdi teose "Cecilia, vergine romana" esiettekanne. P.Järvi kontsertidest detsembris Euroopas

  19. Otvedaite "Ljubovnõi napitok"

    Index Scriptorium Estoniae

    1999-01-01

    Majakovski nim. Akadeemilise Teatri külalisetendused Tallinnas 16. ja 17. mail Vene Draamateatris.Etendatakase Tatjana Ahramkova lavastuses "Armujooki" Peter Shafferi näidendi "Lettice and Lovage" järgi. Peaosas näitleja Natalja Gundareva

  20. Tšehhov - ilma ainsagi sõnata / Boris Tuch

    Index Scriptorium Estoniae

    Tuch, Boris, 1946-

    2004-01-01

    Festivali külalisest Valgevene Janka Kupala nim. Valgevene Akad. Rahvusteatrist ja P. Adamtshikovi fantaasiast "S.V." A. Tšehhovi "Kirsiaia" ainetel. Lisatud E. Kekelidze mulje etendusest, mida ta nägi ülevenemaalisel festivalil Peterburis

  1. Odnoi krovi s Dostojevskim / Ksenia Repson

    Index Scriptorium Estoniae

    Repson, Ksenia

    2006-01-01

    5.-7. juulini toimuvad Estonia teatris Moskva Mossoveti-nim. Teatri külalisetendused. Mängitakse Juri Jerjomini lavastusi "Mees, naine ja armuke" (F. Dostojevski ja I. Turgenevi teoste põhjal) ja Tennessee Williamsi "Tramm nimega iha"

  2. Rulison Site corrective action report

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-09-01

    Project Rulison was a joint US Atomic Energy Commission (AEC) and Austral Oil Company (Austral) experiment, conducted under the AEC`s Plowshare Program, to evaluate the feasibility of using a nuclear device to stimulate natural gas production in low-permeability gas-producing geologic formations. The experiment was conducted on September 10, 1969, and consisted of detonating a 40-kiloton nuclear device at a depth of 2,568 m below ground surface (BGS). This Corrective Action Report describes the cleanup of petroleum hydrocarbon- and heavy-metal-contaminated sediments from an old drilling effluent pond and characterization of the mud pits used during drilling of the R-EX well at the Rulison Site. The Rulison Site is located approximately 65 kilometers (40 miles) northeast of Grand Junction, Colorado. The effluent pond was used for the storage of drilling mud during drilling of the emplacement hole for the 1969 gas stimulation test conducted by the AEC. This report also describes the activities performed to determine whether contamination is present in mud pits used during the drilling of well R-EX, the gas production well drilled at the site to evaluate the effectiveness of the detonation in stimulating gas production. The investigation activities described in this report were conducted during the autumn of 1995, concurrent with the cleanup of the drilling effluent pond. This report describes the activities performed during the soil investigation and provides the analytical results for the samples collected during that investigation.

  3. Courses and syllabus: the situation in Greece

    International Nuclear Information System (INIS)

    Hadjiantoniou, A.

    1989-01-01

    The existing legislation and the Euratom Basic Safety Standards which are now part of it, provide for the information and training of workers in radiation protection. The Greek AEC being the competent authority for providing information and training in radiation protection has made a considerable effort to train the workers employed at the Demokritos NRCPS as well as those persons working in the medical, industrial, research, educational and other applications of ionizing radiation. At the Demokritos Center the on the job training of the radiation workers was considered appropriate. The occasionally exposed workers e.g. the repair and maintenance personnel, the plumbers, the unskilled workers, the security personnel the janitors e.c.t. have attended an one day seminar in radiation protection, focused on practical matters concerning safety. The Greek AEC has also provided training for the exposed or occasionally exposed workers employed elsewhere. This training was mainly for those working in the medical applications of ionizing radiation and to a lesser extent to persons working in other applications. The radiation workers and the occasionally exposed workers were trained together. There is a need for training of certain groups of persons who may be concerned by activities which involve ionizing radiation. These groups are, policemen, firemen, labor union officials e.t.c. So far the Greek AEC has not provided such a training. The Greek AEC should make an effort for a more systematic, program for information and training of workers in radiation protection

  4. Potential Conflict Among ASEAN Member States in The Implementation of The ASEAN Economic Community

    Directory of Open Access Journals (Sweden)

    Sugiarto Pramono

    2017-08-01

    Full Text Available The findings in this article defy the common assumption that the free market, including the formation of the ASEAN Economic Community (AEC in Southeast Asia, is correlated with the creation of a spillover and complex interdependency, reducing conflicts between countries in the region. This finding could well contribute as a theory in the academic sphere and as policies in the practical world. The author uses a theoretical framework of structural realism to explain the potential conflict between countries of the Southeast Asian region. There are four potential conflict situations among countries in the implementation of AEC: firstly, the structure of economic disparity. This situation would construct an identity of in-group – out-group or “us” versus “them” in the context of who gains and loses in the AEC. Secondly, similarity of natural resources. This fact led the Southeast Asian countries to compete and create standardization wherein each party is in hostile competition to claim valid findings and arguments associated with efforts to reduce or stop the flow of imports into their respective countries. Thirdly, competition among businesses, in which AEC constructed free market could potentially provoke the emergence of regional trading cartel. Fourthly, the structure of military power. Historical records show that any economic growth occurring in a country will be accompanied by the growth of its military budget.

  5. Uudised : Marko Martini konkursiedu Kanadas. "Con brio" lõppkontserdile 6 esinejat. Tublid noored trompetistid / Joosep Sang

    Index Scriptorium Estoniae

    Sang, Joosep

    2000-01-01

    M. Martin pälvis II koha III Esther Honensi nim. pianistide konkursil Kanadas. Konkursi "Con brio" lõppvooru pääsejatest. N. ja J.Ots olid edukad I rahvusvahelisel noorte trompetistide konkursil Jekabpilsis Lätis

  6. Encapsulated Curcumin for Transdermal Administration

    African Journals Online (AJOL)

    Erah

    Faculty of Pharmacy, University of Benin, ... Institute of Pharmacy, NIMS University, Jaipur, 303121, Rajasthan, Global Institute of .... securely attached on one side. ..... Clinic.Biochem. 2002: 17(12): 33-43. 13. Garg SK. Effect of Curcuma longa ...

  7. The ASEAN Economic Community Project

    DEFF Research Database (Denmark)

    Juego, Bonn

    2014-01-01

    In this paper, I attempt to unpack the ASEAN Economic Community (AEC) Blueprint to reveal the project’s neoliberal capitalist strategy of ‘accumulation by dispossession’ whereby the drive for the acquisition of more wealth and power by the economically wealthy and politically powerful necessitated...... the deprivation of the peoples’ collective rights and access to the economic, political, social, and ecological commons. I therefore offer a critical reading of the AEC project in the analysis, specifically its agenda for the establishment of a competitive single market, and conclude with some notes...

  8. An examination of the relationship between CSR disclosure and financial performance: The case of Polish banks

    Directory of Open Access Journals (Sweden)

    Łukasz Matuszak

    2017-12-01

    Full Text Available The purpose of this study is twofold. First, this study investigates the trends of corporate social responsibility (CSR reporting and financial performance (FP in commercial banks in Poland. Second, this study examines the impact of the CSR disclosure of the banks on their financial performance (ROA, ROE, NIM. Sample consists of 18 banks. The data from annual reports for the period of 8 years (2008 – 2015 were both hand collected and obtained from Notoria Servis Database. A content analysis is used to measure the level of CSR disclosures and a panel data analysis is employed to examine the CSR-FP relationship. Software: GRETL. Two key findings: (1 Positive relationship between banks’ CSR disclosures and their profitability measured by ROA and ROE. However, the relationship between banks’ CSR disclosures and NIM is negative. Statistical analysis did not report any significant effect of CSR activities on ROA, ROE and NIM ratios. (2 Banks’ CSR activities are not dominant predictor of their profitability as compared with control variables. To our best knowledge this research is the first quantitative analysis regarding banking sector in Poland. Further, this study was conducted in emerging market with different socio-economic context and regulations compared to developed market. The findings contribute to and increase the understanding of the relationship between CSR disclosures and FP. Finally, this study has important implications for policy makers, managers, investors, and others.

  9. Development and Validation of a Versatile UPLC-PDA Method for Simultaneous Determination of Paracetamol, Tizanidine, Aceclofenac, and Nimesulide in Their New Combinations

    Directory of Open Access Journals (Sweden)

    Sami Bawazeer

    2018-01-01

    Full Text Available A simple, rapid, and validated UPLC method was developed for the simultaneous quantitation of paracetamol (PAR, tizanidine (TIZ, aceclofenac (ACF, and nimesulide (NIM either in pure forms or in their different tablet dosage forms. Chromatographic separation was attained on an ACQUITY UPLC™ BEH C18 column (100 mm × 2.1 mm, 1.7 μm with a mobile phase consisting of 20 mM phosphate buffer (pH 7.0 : acetonitrile in the proportion (60 : 40 v/v isocratically pumped at a flow rate of 1.25 mL·min−1, and detection was monitored at 305 nm. All analytes were separated simultaneously at a retention time (tr of 1.42, 2.31, 3.63, and 5.62 min for PAR, TIZ, ACF, and NIM, respectively, with a total run time less than 6.0 min. The proposed method was validated according to ICH guidelines with respect to accuracy, precision, linearity, limit of detection, limit of quantitation, and robustness. Linearity was obtained over a concentration range of 81.25–487.5, 0.5–3.5, 25–150, and 25–150 µg·mL−1 for PAR, TIZ, ACF, and NIM, respectively. The development method can be successfully employed in QC laboratories for the routine analysis of the investigated drugs in their new combination.

  10. Evaluating the clinical utility of the Validity-10 for detecting amplified symptom reporting for patients with mild traumatic brain injury and comorbid psychological health conditions.

    Science.gov (United States)

    Dretsch, Michael N; Williams, Kathy; Staver, Tara; Grammer, Geoffrey; Bleiberg, Joseph; DeGraba, Thomas; Lange, Rael T

    2017-01-01

    The objective of this study was to compare the Validity-10 scale with the PAI Negative Impression Management Scale (PAI-NIM) for detecting exaggerated symptom reporting in active-duty military service members (SMs) admitted with unremitting mild TBI symptoms and comorbid psychological health conditions (mTBI/PH). Data were analyzed from 254 SMs who completed the Neurobehavioral Symptom Inventory (NSI) and Personality Assessment Inventory (PAI) as a part of a larger battery of self-report symptom scales upon admission to the intensive-outpatient TBI treatment program at a military medical center. Symptom exaggeration was operationalized using the PAI Negative Impression Management Scale (PAI-NIM). A PAI-NIM score of ≥73 was categorized as positive for symptom exaggeration (SVTpos), while a lower score was categorized as negative for symptom exaggeration (SVTneg). SMs in the SVTpos group (n = 34) had significantly higher scores (p ≤ .004) on the PAI clinical scales as well as on the NSI total score (range: d = 0.59-1.91) compared to those who were SVTneg (n = 220). The optimal cut-score for the NSI Val-10 scale to identify possible symptom exaggeration was ≥26 (sensitivity = .29, specificity = .95, PPP = .74, NPP = .71). In patients suffering from mTBI/PH, the Validity-10 requires a higher cut-score than previously reported to be useful as a metric of exaggerated symptom reporting.

  11. Uudised : Hortus Musicus Moskvas. TPÜ naiskoor koorikonkursil. RAM samal laval Mark Knopfleriga. "Tuuleveskid. Kerkokell" / Joosep Sang

    Index Scriptorium Estoniae

    Sang, Joosep

    2000-01-01

    Hortus Musicus esines 23. ja 24. nov. Moskvas. TPÜnaiskoor võitis II preemia XVII rahvusvahelisel F.Schuberti nim. koorikonkursil Austrias. RAM esineb 8. dets. Helsingis Hartwall Areenas heategevuskontserdil. RAM esineb 6. dets. Estonia kontserdisaalis kavaga "Tuuleveskid. Kerkokell"

  12. Linnapea autasustas tublisid arvutajaid / Liisi Seil

    Index Scriptorium Estoniae

    Seil, Liisi, 1971-

    2009-01-01

    Viljandi linnapea Kalle Jents võttis vastu August Maramaa nimelise matemaatikaülesannete lahendamise võistluse võitjad, nende õpetajad ja võistluse korraldajad. Eriauhinna pälvis Carl Robert Jakobsoni nim. Gümnaasiumi õpilane Siim-Ilmar Nopri

  13. Muusikamaailm : New Yorki tuleb Maazel. Kiri ei lahku veel lavalt. Kennedy Centeri autasud. Opera Internationali ankeet / Priit Kuusk

    Index Scriptorium Estoniae

    Kuusk, Priit, 1938-

    2001-01-01

    L.Maazel valiti NY Filharmoonikute uueks peadirigendiks alates 2002.a., dirigendi praegustest tegemistest. K.Te Kanawa jätkab lauljategevust. Washingtoni Kennedy nim. kunstikeskuse aasta autasudest. Muusikaajakiri Opera Internationali lugejad valisid 20. saj. suurimad ooperilauljad, dirigendid ja lavastajad

  14. Nuclear Research and Development in the AEC Era

    International Nuclear Information System (INIS)

    Mongkolnavin, R.

    2014-01-01

    In 2015, South East Asian Countris are entering into the social, economic and security partnership. Nuclear Research and Development undoubtedly has important roles in all three pillars. Nuclear applications that are being realised in the region ranges from energy, mrdical to agricultural application.In this new era of cooperation, we are seeking for technologies that lead to solution to improve our ways of living. As all other research and development nuclear research has been carried out in all countries in the region. However, it does have its critiques on safety issues based on people capability in the region. In order to make progress in research and development, human resource development is the key fundamental to its sucess. An experience of regional collaboration in developing pulsed neutron souurce is presented as an example. The research had been revived though collaoration of different research laboratories within ASEAN countries with support of Asian African Assosiation for Plasma Training (AAAPT). The 'low cost research theme' has fundamentally set up a platform for more future advanced research for fusion and for local industrial applications. It also increases experimental and theoretical research awareness among new generations that could be carried out in local laboratories. A device such as UNU-ICPT Plasma Focus has been explored, and it has been built, studied; both theoretical and experimental; and used for many different kind of applications.

  15. Expert System Techniques and Applications in AEC-Design

    DEFF Research Database (Denmark)

    Andersen, Tom

    This part of a book presents expert system techniques applicable to building design and construction, and it reports and evaluates on systems developed in thar domain.......This part of a book presents expert system techniques applicable to building design and construction, and it reports and evaluates on systems developed in thar domain....

  16. A/E/C CAD Standard, Release 5.0

    Science.gov (United States)

    2012-12-01

    DMPR Dampers 0 0.35 22 22 X X Graphic Defaults Model File Types CO2 Sprinkler System Aqueous Film Forming Foam System Means of Egress Lighting...45 X E-POWR- GENR Generators and auxiliary equipment 0 0.50 4 7 X E-POWR-JBOX Junction boxes, pull boxes, manholes, handholes, pedestals, splices 0

  17. A/E/C CAD Standard, Release 4.0

    Science.gov (United States)

    2009-07-01

    Bath .....................D8-23 BATHEM – Emergency Bath .............D8-23 BATHFT – Foot Bath..........................D8-23 BATHHA – Hydrotherapy ...Arm Bath .D8-23 BATHHH – Hydrotherapy Hubbard Bath................................D8-23 BATHHL – Hydrotherapy Leg Bath...D8-23 BATHIF – Infant

  18. The French A.E.C. nuclear robotic program

    International Nuclear Information System (INIS)

    Foult, T.

    1991-01-01

    The new French nuclear robotic program launched by the CEA was started at the beginning of 1988 for the duration of two years and with the total subsidy of about 130 million French franc. This program includes the following four steps: the definition of model missions dedicated to inspection and intervention in nuclear environment, the system analysis to define the systems, functions and specifications required to perform these model missions, the technological development required to achieve these systems, and the design of demonstration models with the partial integration of the above developments. The whole program including these four steps is called SYROCO (modular SYstem for RObots COoperating in radioactive environment). The repair of leak in a pipe in a reprocessing cell, the model mission in a PWR nuclear power plant, autonomous load bearing mobile robots, squirrel concept light modular carrier concept, radiation hardening, mechanic, perception of environment, communication, control and simulation and the demonstration models are described. SHERPA project, perception management, force controlled manipulator, squirrel project, light modular carrier, processes and NAB model mission simulation are particularly mentioned

  19. Present and future status of distributed database for nuclear materials (Data-Free-Way)

    International Nuclear Information System (INIS)

    Fujita, Mitsutane; Xu, Yibin; Kaji, Yoshiyuki; Tsukada, Takashi

    2004-01-01

    Data-Free-Way (DFW) is a distributed database for nuclear materials. DFW has been developed by three organizations such as National Institute for Materials Science (NIMS), Japan Atomic Energy Research Institute (JAERI) and Japan Nuclear Cycle Development Institute (JNC) since 1990. Each organization constructs each materials database in the strongest field and the member of three organizations can use these databases by internet. Construction of DFW, stored data, outline of knowledge data system, data manufacturing of knowledge note, activities of three organizations are described. On NIMS, nuclear reaction database for materials are explained. On JAERI, data analysis using IASCC data in JMPD is contained. Main database of JNC is experimental database of coexistence of engineering ceramics in liquid sodium at high temperature' and 'Tensile test database of irradiated 304 stainless steel' and 'Technical information database'. (S.Y.)

  20. A histogram memory plug-in board for IBM-PC based nuclear pulse height analysis applications

    International Nuclear Information System (INIS)

    Behere, Anita; Ghodgaonkar, M.D.

    1989-01-01

    The histogram memory PC plug-in board has 8K x 24 dual ported memory with access from PC as well as from on board data acquisition logic. The arbitration control logic monitors the memory access requests from both the sources and honours them on first come first served basis. The data acquisition logic takes only 840 ns. to perform Read-Modify-Write memory operation. The data acquisition logic incorporates ADC interface logic for connecting to a NIM ADC which is normally housed in a NIM system along with other required front-end processing modules. Two interval timers are provided on the board. One of them provides Live Time/Clock Time counting and the other generates a 200 ms interrupt which is used for live spectrum display. The board is fully supported with system and data processing software developed in Turbo Pascal. (author)

  1. SU-G-IeP3-02: Characteristics of In-Vivo MOSFET Dosimeters for Diagnostic X-Ray Low-Dose Measurements

    Energy Technology Data Exchange (ETDEWEB)

    Li, S; Ali, S; Harper, K; Liang, Q; Serratore, D [Temple University Hospital, Philadelphia, PA (United States)

    2016-06-15

    Purpose: To correct in-vivo metal-oxide-semiconductor field-effect transistor (MOSFET) dosimeters dependence on X-ray energy, dose and dose rate, and temperature in order to measure doses or exposures on several anatomic points of interest undergoing some routine radiographs. Methods: A mobile MOSFET system (BEST Medical) was carefully calibrated with X-ray at kVp of 70, 80, 100, 120, and 138 kVp, phantom temperatures at 0, 21, and 43 oC, and exposure range from 0.01 to 10 R confirmed with Raysafe and RadCal dosimeters. The MOSFETS were placed on the midline bladder or uterus, left pelvic iliac artery, left abdominal above iliac crest, abdominal midline anterior at inferior margin of stomach, and left pectoral of a large and a small body-size cadavers undergoing AP/PA chest and lumber spine radiographs using manual and automatic exposure control (AEC) with and without lead shielding. MOSTFETs and TLD chips were also placed on the stomach, sigmoid, pubic symphysis, left and right pelvic walls of another cadaver for AP pelvic manual or AEC radiography prior to and after a left hip metal implant. Results: Individual MOSFET detectors had various low-dose limits in ranged from 0.03 to 0.08 R, nonlinear response to X-ray energy, and significant temperature effect of 15%. By accumulating 10 manual exposures and 20 AEC exposures, we achieved dose measured accuracy of 6%. There were up to 8 fold increases for AEC exposure of spine and chest X-ray procedure from no shielding to with shielding. For pelvic radiography, exposure to public symphysis was the highest even higher than that of the skin. After hip implant, AEC pelvic radiograph increase exposure by 30 to 200% consistent with results of TLDs. Conclusion: Dependence of energy, temperature and dose limit were accurately corrected. We have found significant exposure for those clinical pr°ocedures and the study provided evidences for developing new clinical procedures.

  2. Tuning of automatic exposure control strength in lumbar spine CT.

    Science.gov (United States)

    D'Hondt, A; Cornil, A; Bohy, P; De Maertelaer, V; Gevenois, P A; Tack, D

    2014-05-01

    To investigate the impact of tuning the automatic exposure control (AEC) strength curve (specific to Care Dose 4D®; Siemens Healthcare, Forchheim, Germany) from "average" to "strong" on image quality, radiation dose and operator dependency during lumbar spine CT examinations. Two hospitals (H1, H2), both using the same scanners, were considered for two time periods (P1 and P2). During P1, the AEC curve was "average" and radiographers had to select one of two protocols according to the body mass index (BMI): "standard" if BMI 30.0 kg m(-2) (140 kV-280 mAs). During P2, the AEC curve was changed to "strong", and all acquisitions were obtained with one protocol (120 kV and 270 mAs). Image quality was scored and patients' diameters calculated for both periods. 497 examinations were analysed. There was no significant difference in mean diameters according to hospitals and periods (p > 0.801) and in quality scores between periods (p > 0.172). There was a significant difference between hospitals regarding how often the "large" protocol was assigned [13 (10%)/132 patients in H1 vs 37 (28%)/133 in H2] (p < 0.001). During P1, volume CT dose index (CTDIvol) was higher in H2 (+13%; p = 0.050). In both hospitals, CTDIvol was reduced between periods (-19.2% in H1 and -29.4% in H2; p < 0.001). An operator dependency in protocol selection, unexplained by patient diameters or highlighted by image quality scores, has been observed. Tuning the AEC curve from average to strong enables suppression of the operator dependency in protocol selection and related dose increase, while preserving image quality. CT acquisition protocols based on weight are responsible for biases in protocol selection. Using an appropriate AEC strength curve reduces the number of protocols to one. Operator dependency of protocol selection is thereby eliminated.

  3. Impact of compressed breast thickness and dose on lesion detectability in digital mammography: FROC study with simulated lesions in real mammograms

    Energy Technology Data Exchange (ETDEWEB)

    Salvagnini, Elena, E-mail: elena.salvagnini@gmail.com [Department of Imaging and Pathology, Radiology, KUL, Herestraat 49, Leuven B-3000 (Belgium); SCK-CEN, Boeretang 200, Mol 2400 (Belgium); Bosmans, Hilde; Marshall, Nicholas W. [Department of Imaging and Pathology, Radiology, KUL, Herestraat 49, Leuven B-3000 (Belgium); Department of Radiology, Radiology, UZ Gasthuisberg, Herestraat 49, Leuven B-3000 (Belgium); Van Ongeval, Chantal; Van Steen, Andreas; Cockmartin, Lesley [Department of Radiology, Radiology, UZ Gasthuisberg, Herestraat 49, Leuven B-3000 (Belgium); Michielsen, Koen [Department of Imaging and Pathology, Nuclear Medicine and Molecular Imaging, KUL, Herestraat 49, Leuven B-3000 (Belgium); Struelens, Lara [SCK-CEN, Boeretang 200, Mol 2400 (Belgium)

    2016-09-15

    Purpose: The aim of this work was twofold: (1) to examine whether, with standard automatic exposure control (AEC) settings that maintain pixel values in the detector constant, lesion detectability in clinical images decreases as a function of breast thickness and (2) to verify whether a new AEC setup can increase lesion detectability at larger breast thicknesses. Methods: Screening patient images, acquired on two identical digital mammography systems, were collected over a period of 2 yr. Mammograms were acquired under standard AEC conditions (part 1) and subsequently with a new AEC setup (part 2), programmed to use the standard AEC settings for compressed breast thicknesses ≤49 mm, while a relative dose increase was applied above this thickness. The images were divided into four thickness groups: T1 ≤ 29 mm, T2 = 30–49 mm, T3 = 50–69 mm, and T4 ≥ 70 mm, with each thickness group containing 130 randomly selected craniocaudal lesion-free images. Two measures of density were obtained for every image: a BI-RADS score and a map of volumetric breast density created with a software application (VolparaDensity, Matakina, NZ). This information was used to select subsets of four images, containing one image from each thickness group, matched to a (global) BI-RADS score and containing a region with the same (local) VOLPARA volumetric density value. One selected lesion (a microcalcification cluster or a mass) was simulated into each of the four images. This process was repeated so that, for a given thickness group, half the images contained a single lesion and half were lesion-free. The lesion templates created and inserted in groups T3 and T4 for the first part of the study were then inserted into the images of thickness groups T3 and T4 acquired with higher dose settings. Finally, all images were visualized using the ViewDEX software and scored by four radiologists performing a free search study. A statistical jackknife-alternative free-response receiver operating

  4. Vsemirnaja teatralnaja Olimpiada : Rossiiski razmahh / Eteri Kekelidze

    Index Scriptorium Estoniae

    Kekelidze, Eteri, 1944-

    2001-01-01

    21. apr. kuni 29. juunini toimub Moskvas Ülemaailmne Teatriolümpiaad ja A. Tšehhovi nim. IV rahvusvaheline teatrifestival, millest võtab osa 150 teatritruppi 50 maalt. Festivalil esines ka Priit Pedajas lavastusega "Lõikuskuu tantsud" Pjotr Fomenko teatris

  5. Õpetajad olid enam-vähem ühed-samad, kuigi koolis käinud olen kolmel ajal / Moja Konno ; üles kirjutanud Ülo Alo Võsar

    Index Scriptorium Estoniae

    Konno, Moja

    2008-01-01

    Ülo Alo Võsari poolt üles kirjutatud lugu Moja Konno õpingutest alguses Viljandi Eesti Haridusseltsi Tütarlastegümnaasiumis, mis riigikorra muutudes pärast 1940. aastat oli sunnitud vahetama nime Carl Robert Jakobsoni nim. Viljandi 1. Keskkooliks

  6. Nuclear Magnetic Resonance Study of Nanoscale Ionic Materials

    KAUST Repository

    Oommen, Joanna Mary; Hussain, Muhammad Mustafa; Emwas, Abdul-Hamid M.; Agarwal, Praveen; Archer, Lynden A.

    2010-01-01

    using nuclear magnetic resonance (NMR) spectroscopy. NIMs are relatively stable over a temperature range from 300 to 383 K, rendering them usable in high temperature applications. We confirmed the presence of covalent bonds between the SiO2 core

  7. National Infrastructure Maintenance Strategy and its implementation

    CSIR Research Space (South Africa)

    Wall, K

    2008-10-01

    Full Text Available The National Infrastructure Maintenance Strategy (NIMS) was approved by Cabinet in 2006. This Strategy sets overarching policy for sector-based initiatives and describes the framework for a coordinated programme of actions. It is an essential part...

  8. Марина Голуб: У меня расчетверение творческой личности! / интервьюировал Николай Хрусталев

    Index Scriptorium Estoniae

    Голуб, Марина, 1957-

    2011-01-01

    Vene näitlejanna Marina Golub räägib endast, oma tööst ja rollidest. Näitleja viibis Tallinnas seoses Moskva Tšehhovi nim. Kunstiteatri külalisetendusega "Vassa Zeleznova", milles ta mängib peaosa

  9. Sequence Classification: 227637 [

    Lifescience Database Archive (English)

    Full Text Available biotics resistance protein, NimA-family || http://www.ncbi.nlm.nih.gov/protein/15895740 ... ...Non-TMB Non-TMH Non-TMB Non-TMB Non-TMB Non-TMB >gi|15895740|ref|NP_349089.1| Possible 5-Nitroimidazole anti

  10. [Lutsuvad kivid : helisalvestis : kirjanikud muusikas / koostanud Aapo Ilves] / Veiko märka

    Index Scriptorium Estoniae

    Märka, Veiko, 1964-

    2013-01-01

    CD “Lutsuvad kivid. Kirjanikud muusikas” on valminud Tartu Oskar Lutsu nim. Linnaraamatukogu ja Tartu kirjandusfestivali Prima Vista ühisel ettevõtmisel, et tähistada kaht sünnipäeva – Lutsu raamatukogu 100 ja Prima Vista 10

  11. A compact four channel scaler with display

    International Nuclear Information System (INIS)

    Ingelman, S.; Wannberg, G.

    1977-03-01

    This note describes the construction of a simple-to-make and inexpensive four channel, four decade scaler with display. The unit is intended for use with standard NIM modules in nuclear counting experiments where counting rates are fairly moderate. (Auth.)

  12. Nastojashtshije spektakli dlja nastojashtshego zritelja / Ella Agranovskaja

    Index Scriptorium Estoniae

    Agranovskaja, Ella, 1950-

    2006-01-01

    5.-7. juulini toimuvad Estonia teatris Moskva Mossoveti-nim. Teatri külalisetendused. Juri Jerjomini lavastus "Mees, naine ja armuke" F. Dostojevski ja I. Turgenevi teoste põhjal, peaosas Valentin Gaft ning lavastus Tennessee Williamsi järgi "Tramm nimega Iha"

  13. Eesti retrospektiivse rahvusbibliograafia kolm köidet ilmunud / Anne Ainz

    Index Scriptorium Estoniae

    Ainz, Anne

    1995-01-01

    Bibl. 3 nim. Kokkuv. inglise k. lk. 151. Rets. rmt.: Eestikeelne raamat 1901-1917. A-P, II R-Y / Toim. Endel Annus. - Tln.: Eesti TA; Eestis ilmunud saksa-, vene- ja muukeelne perioodika 1675-1940 / Toim. E. Annus. Tln. : Eesti TA, 1993

  14. Kas Euroopa saab Euroopaks? / Timothy Garton Ash ; tõlk. Aet Varik

    Index Scriptorium Estoniae

    Garton Ash, Timothy, 1955-

    2002-01-01

    3. aprillil 1996 peetud Sanford S. Elbergi nim. loeng California Ülikooli (Berkeley) Rahvusvaheliste Uuringute Instituudis. Euroopa määratlus enne 1945. aastat, 1945-1989, külma sõja järgsel perioodil ja tänapäeval

  15. Effect of processing variables and in-vitro study of microparticulate system of nimesulide Efeito de variáveis do processo e estudo in vitro de sistema microparticulado de nimesulida

    Directory of Open Access Journals (Sweden)

    Kamlesh Dashora

    2007-12-01

    Full Text Available Microparticulate systems of nimesulide (NIM were prepared by modified solvent evaporation method using different variables such as polymer: drug (NIM ratios (cellulose acetate, CA: nimesulide, NIM (1:9, 1:6 and 1:3, agitation speeds (500-1500 rpm and stirring time (15-30 min. The effects of processing variables were evaluated by microparticle size and entrapment efficiency. The average microparticle size increases from 66.8±1.45 to 87.3±1.06 µm with increase in the polymer concentration while reduces with increase in agitation speed and stirring time; but at the too higher speed gives irregular shape of particles. The highest entrapment efficiency (77.83±0.51%, size uniformity, free flowability, i.e., angle of repose (23.5±0.4º and compressibility index (14.2±0.6%, of microparticles were found with 1:6 (polymer: drug ratio, at 1000 rpm and 20 min stirring time among all prepared microparticles (P Prepararam-se sistemas microparticulados de nimesulida (NIM pelo método modificado de evaporação do solvente usando diferentes variáveis, tais como proporções polímero fármaco(NIM (acetato de celulose, CA: nimesulida, NIM (1:9, 1:6 e 1:3, velocidades de agitação (500-1500 rpm e tempo de agitação (15-30 min. Os efeitos das variáveis do processo foram avaliados pelo tamanho da partícula e pela eficiência no encapsulamento. O tamanho médio das micropartículas aumenta de 66,8±1,45 a 87,3±1,06 µm com o aumento na concentração de polímero, enquanto reduz com o aumento da velocidade e do tempo de agitação, mas velocidades mais altas resultam em partículas de formas irregulares. A eficácia de encapsulamento mais alta (77,83±0,51%, uniformidade de tamanho, fluxo livre, isto é, ângulo de repouso (23,5±0,4º, e índice de compressibilidade (14,2±0,6%, das micropartículas foram encontrados com a proporção de 1:6 (polímero:fármaco, a 1000 rpm e 20 min de tempo de agitação entre todas as micropartículas preparadas (P < 0

  16. Establishing capabilities for combating illicit trafficking: the Syrian experience

    International Nuclear Information System (INIS)

    Othman, I.; Suman, H.

    2008-01-01

    Since the late 80's, Syria has been taking steps towards combating illicit trafficking or inadvertent movement involving radioactive or nuclear material within the country or across its border. By applying the proper combination of technical and procedural measures, an acceptable level of performance has been achieved. The measures undertaken by AECS include anticipative measures, which aim at identifying potential loss of control over radioactive sources and potential illicit trafficking within the country, as well as defensive measures which aim at detection of and response to events of illicit trafficking. In addition, a tight follow up of radiation source along their entire lifetime in the Syrian territory, supported by proper data analysis is one of the most efficient tools for identifying potential loss of control over sources. AECS has established Border Monitoring Centers (BMC) in almost all border crossings. They work in close cooperation with the customs and other relevant authorities at the Syrian borders. AECS has been also providing the necessary training for the frontline officers. (author)

  17. Establishing capabilities for combating illicit trafficking: the Syrian experience

    International Nuclear Information System (INIS)

    Othman, I.; Suman, H.

    2008-01-01

    Since the late 80 's, Syria has been taking steps towards combating illicit trafficking or inadvertent movement involving radioactive or nuclear material within the country or across its border. By applying the proper combination of technical and procedural measures, an acceptable level of performance has been achieved. The measures undertaken by AECS include anticipative measures, which aim at identifying potential loss of control over radioactive sources and potential illicit trafficking within the country, as well as defensive measures which aim at detection of and response to events of illicit trafficking. In addition, a tight follow up of radiation source along their entire lifetime in the Syrian territory, supported by proper data analysis is one of the most efficient tools for identifying potential loss of control over sources. AECS has established Border Monitoring Centers (BMC) in almost all border crossings. They work in close cooperation with the customs and other relevant authorities at the Syrian borders. AECS has been also providing the necessary training for the front-line officers. (author)

  18. OBTENCIÓN DE FRACCIONES ENRIQUECIDAS DURANTE LA EXTRACCIÓN DE ACEITES ESENCIALES CRUDOS

    Directory of Open Access Journals (Sweden)

    María S. Guala

    2012-01-01

    Full Text Available La destilación por arrastre con vapor es uno de los métodos más utilizados para la obtención de aceite esencial crudo (AEC. Muchas aplicaciones requieren fracciones de AEC, enriquecidas en un componente o grupo de ellos, para lo cual se utiliza destilación al vacío. En este trabajo se propone realizar un fraccionamiento del aceite esencial crudo (AEC durante el proceso de extracción por destilación con arrastre de vapor, para lo cual se colectaron distintos cortes, en lugar de una única mezcla final que es la metodología tradicionalmente utilizada. Las experiencias se llevaron a cabo utilizando frutos, hojas y tallos de aguaribay (Schinus molle L.. La composición de las distintas muestras obtenidas se determinó por cromatografía gaseosa acoplada a espectroscopía de masas. Los resultados muestran diferentes componentes (y concentraciones para los diferentes cortes, lo que indica que se puede lograr una apreciable separación utilizando esta metodología.

  19. Controlling the atom. The beginnings of nuclear regulation 1946--1962

    Energy Technology Data Exchange (ETDEWEB)

    Mazuzan, G.T.; Walker, J.S.

    1997-08-01

    This book traces the early history of nuclear power regulation in the US. It focuses on the Atomic Energy Commission (AEC), the federal agency that until 1975 was primarily responsible for planning and carrying out programs to protect public health and safety from the hazards of the civilian use of nuclear energy. It also describes the role of other groups that figured significantly in the development of regulatory policies, including the congressional Joint Committee on Atomic Energy, federal agencies other than the AEC, state governments, the nuclear industry, and scientific organizations. And it considers changes in public perceptions of and attitudes toward atomic energy and the dangers of radiation exposure. The context in which regulatory programs evolved is a rich and complex mixture of political, legislative, legal, technological, scientific, and administrative history. The basic purpose of this book is to provide the Nuclear Regulatory Commission (NRC), which inherited responsibility for nuclear safety after Congress disbanded the AEC, and the general public with information on the historical antecedents and background of regulatory issues.

  20. The United States experience in the transfer of nuclear tecnology

    International Nuclear Information System (INIS)

    Thorne, R.D.

    1977-01-01

    The paper surveys U.S. public policies and program for nuclear energy development. In the U.S., nuclear technology has been applied for public benefit. Today it is being relied on to meet electrical power requirements. Radioisotope technology is being applied in industry, agriculture and medicine. In 1947 when AEC was established, nuclear technologies moved from research and development phase to useful products and processes. After energy shortages in 1974, a new agency (ERDA) was created, which brought together research and development programs in solar, geothermal and fossil, as well as energy systems. The Atomic Energy Act was amended in 1954 to permit cooperation with foreign countries. Domestically, the AEC engaged in a series of Power Reactor Demonstration with U.S. industry that in a decade led to the demonstration of proven and economic light-water reactors. In 1957 IAEA was established, and then the whole series of AEC policy changed by a strong information dissemination program. ERDA unified the Government's effort to provide a variety of energy choices in nuclear and non-nuclear areas

  1. Atividade inseticida in vitro do óleo de sementes de nim sobre Lutzomyia longipalpis (Diptera: Psychodidae In vitro insecticidal activity of seed neem oil on Lutzomyia longipalpis (Diptera: Psychodidae

    Directory of Open Access Journals (Sweden)

    Michelline V. Maciel

    2010-03-01

    Full Text Available Lutzomyia longipalpis é o principal vetor da Leishmaniose visceral no Brasil. O objetivo deste trabalho foi avaliar o efeito do óleo de sementes de nim (Azadirachta indica sobre ovos, larvas e adultos do vetor. Os insetos foram capturados no campo e mantidos no laboratório a ± 27 °C e 80% de umidade relativa. Cinco tratamentos com diferentes concentrações foram realizados, usando-se dois controles negativos, um com água destilada e outro com Tween 80 (3% e um controle positivo com cipermetrina. Os ovos foram borrifados com o óleo em diferentes concentrações e avaliou-se o número de larvas eclodidas por 10 dias consecutivos. A mortalidade das larvas foi observada até a pupação, e a mortalidade dos adultos foi observada após 24, 48, e 72 horas. A análise estatística foi feita pelo teste de Tukey a 5% de probabilidade. No teste com ovos, a maior concentração obteve 65,16 ± 3,24% de eficácia. O teste com larvas apresentou 67,75 ± 2,21% de eficácia na concentração de 100 mg.mL-1. Com adultos, a eficácia na concentração de 100 mg.mL-1 foi de 96,64 ± 4,11%, após 24 horas. A análise fitoquímica revelou a presença de triterpenos. Esses resultados demonstram o potencial uso desse óleo no controle deste vetor.Lutzomyia longipalpis is the main vector of visceral leishmaniasis in Brazil. The objective was to evaluate the effect of oil from (Azadirachta indica neem seeds on eggs, larvae and adults of the vector. The insects were captured in the field and kept in the laboratory at ± 27 °C and 80% relative humidity. Five treatments with different concentrations were performed using two negative controls (distilled water and Tween 80 and a positive control. The eggs were sprayed with the oil at different concentrations and the number of hatched larvae evaluated for 10 days. Mortality of larvae was observed to pupation and adult mortality was observed after 24, 48, and 72 hours. Statistical analysis was performed by Tukey test

  2. Modeling pulmonary fibrosis by abnormal expression of telomerase/apoptosis/collagen V in experimental usual interstitial pneumonia

    International Nuclear Information System (INIS)

    Parra, E.R.; Pincelli, M.S.; Teodoro, W.R.; Velosa, A.P.P.; Martins, V.; Rangel, M.P.; Barbas-Filho, J.V.; Capelozzi, V.L.

    2014-01-01

    Limitations on tissue proliferation capacity determined by telomerase/apoptosis balance have been implicated in pathogenesis of idiopathic pulmonary fibrosis. In addition, collagen V shows promise as an inductor of apoptosis. We evaluated the quantitative relationship between the telomerase/apoptosis index, collagen V synthesis, and epithelial/fibroblast replication in mice exposed to butylated hydroxytoluene (BHT) at high oxygen concentration. Two groups of mice were analyzed: 20 mice received BHT, and 10 control mice received corn oil. Telomerase expression, apoptosis, collagen I, III, and V fibers, and hydroxyproline were evaluated by immunohistochemistry, in situ detection of apoptosis, electron microscopy, immunofluorescence, and histomorphometry. Electron microscopy confirmed the presence of increased alveolar epithelial cells type 1 (AEC1) in apoptosis. Immunostaining showed increased nuclear expression of telomerase in AEC type 2 (AEC2) between normal and chronic scarring areas of usual interstitial pneumonia (UIP). Control lungs and normal areas from UIP lungs showed weak green birefringence of type I and III collagens in the alveolar wall and type V collagen in the basement membrane of alveolar capillaries. The increase in collagen V was greater than collagens I and III in scarring areas of UIP. A significant direct association was found between collagen V and AEC2 apoptosis. We concluded that telomerase, collagen V fiber density, and apoptosis evaluation in experimental UIP offers the potential to control reepithelization of alveolar septa and fibroblast proliferation. Strategies aimed at preventing high rates of collagen V synthesis, or local responses to high rates of cell apoptosis, may have a significant impact in pulmonary fibrosis

  3. Management of roads with abnormal radiation

    International Nuclear Information System (INIS)

    Chen Wenfang; Huang Jehnying; Chin, Chingjer; Chen Yibin

    2002-01-01

    Several asphalt concrete (AC) roads in Taoyuan County of Taiwan were found radioactively abnormal in 1994. Atomic Energy Council (AEC), the regulatory agency, was asked to take the samples, to perform the radiochemical analysis and dose evaluation as well as to investigate the source of contamination. The cause of high radiation was due to high uranium and thorium concentration slag used in the AC. The dose rate was approximately 1 μSv/hr at the road surface. The maximum annual dose received by pedestrians was estimated at 0.13 mSv (2.5% of annual dose limit of 5 mSv for the public), or approximately 1/15 of the value of annual natural background radiation in the Taiwan area. Consequently, the AEC suggested that there was no need to implement engineering remedy measures to remove the AC surface of the roads. However, upon consideration of socioeconomic condition and public opinion, the local government still decided to remove the contaminated surface of these roads. The AEC helped to formulate the operational procedures for removal and disposal of the AC including the radiation protection program and the disposal site. To date, all the contaminated AC surface of the roads was removed and properly disposed. The contaminated AC roads are a typical example of improper disposal of wastes containing Technologically Enhanced Naturally Occurring Radioactive Materials (TENORM). A new regulation was promulgated by AEC recently to limit the use of slag, coal ash or any other industrial wastes unless its radiation or activity level is below the limit. (author)

  4. Modeling pulmonary fibrosis by abnormal expression of telomerase/apoptosis/collagen V in experimental usual interstitial pneumonia

    Energy Technology Data Exchange (ETDEWEB)

    Parra, E.R.; Pincelli, M.S. [Departamento de Patologia, Faculdade de Medicina, Universidade de São Paulo, São Paulo, SP (Brazil); Teodoro, W.R.; Velosa, A.P.P. [Disciplina de Reumatologia, Faculdade de Medicina, Universidade de São Paulo, São Paulo, SP (Brazil); Martins, V.; Rangel, M.P.; Barbas-Filho, J.V.; Capelozzi, V.L. [Departamento de Patologia, Faculdade de Medicina, Universidade de São Paulo, São Paulo, SP (Brazil)

    2014-06-04

    Limitations on tissue proliferation capacity determined by telomerase/apoptosis balance have been implicated in pathogenesis of idiopathic pulmonary fibrosis. In addition, collagen V shows promise as an inductor of apoptosis. We evaluated the quantitative relationship between the telomerase/apoptosis index, collagen V synthesis, and epithelial/fibroblast replication in mice exposed to butylated hydroxytoluene (BHT) at high oxygen concentration. Two groups of mice were analyzed: 20 mice received BHT, and 10 control mice received corn oil. Telomerase expression, apoptosis, collagen I, III, and V fibers, and hydroxyproline were evaluated by immunohistochemistry, in situ detection of apoptosis, electron microscopy, immunofluorescence, and histomorphometry. Electron microscopy confirmed the presence of increased alveolar epithelial cells type 1 (AEC1) in apoptosis. Immunostaining showed increased nuclear expression of telomerase in AEC type 2 (AEC2) between normal and chronic scarring areas of usual interstitial pneumonia (UIP). Control lungs and normal areas from UIP lungs showed weak green birefringence of type I and III collagens in the alveolar wall and type V collagen in the basement membrane of alveolar capillaries. The increase in collagen V was greater than collagens I and III in scarring areas of UIP. A significant direct association was found between collagen V and AEC2 apoptosis. We concluded that telomerase, collagen V fiber density, and apoptosis evaluation in experimental UIP offers the potential to control reepithelization of alveolar septa and fibroblast proliferation. Strategies aimed at preventing high rates of collagen V synthesis, or local responses to high rates of cell apoptosis, may have a significant impact in pulmonary fibrosis.

  5. Reduction of FR900525 using an S-(2-aminoethyl) l-cysteine-resistant mutant.

    Science.gov (United States)

    Shimizu, Shiho; Futase, Ayako; Yokoyama, Tatsuya; Ueda, Satoshi; Honda, Hiroyuki

    2017-06-01

    FK506 (tacrolimus), a macrolide compound with immunosuppressant activity, has been proven to have clinical importance and has been manufactured industrially since 1993 by using mutants with high FK506-production ability; these mutants have been developed from the wild strain Streptomyces tsukubaensis No. 9993. FR900525 is one of the by-products of FK506 production. However, there was no effective industrial method to separate FR900525 from FK506 due to the structural similarity between the two compounds. Therefore, reducing the level of FR900525 was a serious problem in the industrial strain A. In this study, we aimed to reduce the FR900525 production. We first determined that pipecolic acid level was a critical parameter for controlling FR900525 production in strain A. S-(2-Aminoethyl) l-cysteine (AEC)-resistant mutants has been reported to increase lysine productivity successfully in a variety of lysine-producing microorganisms. Therefore, next, we applied a selection of AEC-resistant mutants to enhance pipecolic acid biosynthesis. Finally, four AEC-resistant mutants were obtained from strain A using ultraviolet irradiation, and three of them showed less FR900525 productivity compared to the parental strain A. Our findings indicated that AEC resistance was effective phenotype marker for increasing pipecolic acid productivity and for reducing FR900525 production in S. tsukubaensis. Thus, our study provides an efficient method for reducing FR90025 level during FK506 biosynthesis. Copyright © 2017 The Society for Biotechnology, Japan. Published by Elsevier B.V. All rights reserved.

  6. Size exclusion and anion exchange high performance liquid chromatography for characterizing metals bound to marine dissolved organic matter

    International Nuclear Information System (INIS)

    García-Otero, Natalia; Bermejo-Barrera, Pilar; Moreda-Piñeiro, Antonio

    2013-01-01

    Highlights: ► Fractionation methods for assessing metals bound to marine DOM were developed. ► SEC and AEC with UV detection and hyphenated with inductively coupled plasma-mass spectrometry were used. ► SEC-UV showed marine DOM of molecular weights from 16 to 1 kDa. ► Cobalt, manganese, strontium and zinc are bound to marine DOM. - Abstract: Size exclusion chromatography (SEC) followed by anion exchange chromatography (AEC) hyphenated with inductively coupled plasma-mass spectrometry (ICP-MS) was applied for fractionating metals bound to marine dissolved organic matter (DOM). Surface seawater samples (100 L) were subjected to tangential flow ultrafiltration (10,000 Da cut off) for isolating and pre-concentrating dissolved large molecules. The isolated fraction (retentate) consisted of 1 L, which was further freeze-dried and re-dissolved to 250 mL with ultrapure water. After HI Trap desalting of the re-dissolved retentate, SEC with UV detection showed marine DOM ranging from 6.5 kDa (lower than the permeable volume of the SEC column) to 16 kDa. A further characterization of this fraction by AEC with UV detection revealed the existence of four groups of macromolecules exhibiting retention times of 2.3, 2.8, 4.5 and 14.0 min. AEC hyphenated with ICP-MS showed the presence of strontium and zinc in the first AE fraction isolated from the SEC fraction; while manganese was found to be bound to the second AE fraction. Cobalt was found to be bound to molecules comprising the third AE fraction.

  7. Indonesian Comparative Advantage Entering the ASEAN Economic Community

    Directory of Open Access Journals (Sweden)

    Riandi .

    2017-03-01

    Full Text Available The purpose of this study is to examine the comparative advantage of Indonesian commodities in order to enter the ASEAN Economic Community (AEC. This study uses the export data during the period of 2003-2013 among five ASEAN countries participating in the AEC, including Indonesia, Malaysia, The Philippines, Singapore, and Thailand. All data obtained from the UN Comtrade database following the Harmonized System (HS at the two-digit classification level. This study applies dynamic revealed comparative advantage (DRCA index developed by Edwards and Schoer (2001 which is the development of revealed comparative advantage (RCA index by Balassa (1965. The results show that Indonesia is ready to enter the AEC. From this research, there are several Indonesian main commodities which have comparative advantage in ASEAN, including fish, crustaceans, molluscs, aquatic invertebrates ones (HS-03, edible fruit, nuts, peel of citrus fruit, melons (HS-08, oil seed, oleagic fruits, grain, seed, fruit, etc, nes (HS-12, lac, gums, resins, vegetable saps and extracts nes (HS-13, rubber and articles thereof (HS-40, paper & paperboard, articles of pulp, paper and board (HS-48, special woven or tufted fabric, lace, tapestry etc (HS-58, articles apparel, accessories, not knit or crochet (HS-62, and vehicles other than railway, tramway (HS-87. Those commodities are in line with Indonesian government export's strategy direction which mainly focuses on several sectors, including fishery, vegetable products, rubber, wood and wood products, textiles, and transportation. Therefore, Indonesian government should focus to improve those commodities in AEC. Keywords: Indonesian Comparative Advantage, Main Export Commodities, Export Strategy Direction, ASEAN Economic Community

  8. A brief history of the air cleaning conferences

    Energy Technology Data Exchange (ETDEWEB)

    First, M.W.

    1995-02-01

    I have been asked to prepare a history of the air cleaning conferences. Undertaking such a task is, of course, a wonderful opportunity for reminiscences and a chance to retell old war stories. I must admit that it has taken much longer than I anticipated because I found myself so completely engrossed rereading the old records that time seemed to stop, although the hours passed. But a history of the nuclear air cleaning conferences means more than a stroll down memory lane. The 23 recorded air cleaning conference proceedings reflect an important aspect of the history of major nuclear developments, both military and civilian, because engineered safety features designed to prevent dispersion of radioactive products to the environment have always been a necessity for progress in this field. For this reason, I hope the history of the nuclear air cleaning conferences will not only be enjoyable, but also have meaning for young people entering this field. The air cleaning conferences were an outgrowth of the operations of the U.S. Atomic Energy Commission`s (AEC) Stack Gas Working Group established in 1948 to review air cleaning operations at AEC installations. AEC`s Division of Engineering sponsored and funded air cleaning research and development at Harvard University`s School of Public Health, beginning about the same time. In addition to research and development, the Harvard contract called for consulting and educational services. The latter provided the opportunity for meetings devoted to information on air cleaning that could be applied to ongoing and anticipated nuclear operations.

  9. SU-E-I-24: Method for CT Automatic Exposure Control Verification

    Energy Technology Data Exchange (ETDEWEB)

    Gracia, M; Olasolo, J; Martin, M; Bragado, L; Gallardo, N; Miquelez, S; Maneru, F; Lozares, S; Pellejero, S; Rubio, A [Complejo Hospitalario de Navarra, Pamplona, Navarra (Spain)

    2015-06-15

    Purpose: Design of a phantom and a simple method for the automatic exposure control (AEC) verification in CT. This verification is included in the computed tomography (CT) Spanish Quality Assurance Protocol. Methods: The phantom design is made from the head and the body phantom used for the CTDI measurement and PMMA plates (35×35 cm2) of 10 cm thickness. Thereby, three different thicknesses along the longitudinal axis are obtained which permit to evaluate the longitudinal AEC performance. Otherwise, the existent asymmetry in the PMMA layers helps to assess angular and 3D AEC operation.Recent acquisition in our hospital (August 2014) of Nomex electrometer (PTW), together with the 10 cm pencil ionization chamber, led to register dose rate as a function of time. Measurements with this chamber fixed at 0° and 90° on the gantry where made on five multidetector-CTs from principal manufacturers. Results: Individual analysis of measurements shows dose rate variation as a function of phantom thickness. The comparative analysis shows that dose rate is kept constant in the head and neck phantom while the PMMA phantom exhibits an abrupt variation between both results, being greater results at 90° as the thickness of the phantom is 3.5 times larger than in the perpendicular direction. Conclusion: Proposed method is simple, quick and reproducible. Results obtained let a qualitative evaluation of the AEC and they are consistent with the expected behavior. A line of future development is to quantitatively study the intensity modulation and parameters of image quality, and a possible comparative study between different manufacturers.

  10. Effect of contrast material on image noise and radiation dose in adult chest computed tomography using automatic exposure control: A comparative study between 16-, 64- and 128-slice CT

    Energy Technology Data Exchange (ETDEWEB)

    Paul, Jijo, E-mail: jijopaul1980@gmail.com [Clinic of the Goethe University, Department of Diagnostic and Interventional Radiology, Haus 23C UG, Theodor-Stern-Kai 7, 60590 Frankfurt am Main (Germany); Goethe University, Department of Biophysics, Max von Laue-Strasse 1, 60438 Frankfurt am Main (Germany); Schell, Boris, E-mail: boris.schell@googlemail.com [Clinic of the Goethe University, Department of Diagnostic and Interventional Radiology, Haus 23C UG, Theodor-Stern-Kai 7, 60590 Frankfurt am Main (Germany); Kerl, J. Matthias, E-mail: matthias.kerl@gmai.com [Clinic of the Goethe University, Department of Diagnostic and Interventional Radiology, Haus 23C UG, Theodor-Stern-Kai 7, 60590 Frankfurt am Main (Germany); Maentele, Werner, E-mail: maentele@biophysik.uni-frankfurt.de [Goethe University, Department of Biophysics, Max von Laue-Strasse 1, 60438 Frankfurt am Main (Germany); Vogl, Thomas J., E-mail: t.vogl@em.uni-frankfurt.de [Clinic of the Goethe University, Department of Diagnostic and Interventional Radiology, Haus 23C UG, Theodor-Stern-Kai 7, 60590 Frankfurt am Main (Germany); Bauer, Ralf W., E-mail: ralfwbauer@aol.com [Clinic of the Goethe University, Department of Diagnostic and Interventional Radiology, Haus 23C UG, Theodor-Stern-Kai 7, 60590 Frankfurt am Main (Germany)

    2011-08-15

    Purpose: To determine the difference in radiation dose between non-enhanced (NECT) and contrast-enhanced (CECT) chest CT examinations contributed by contrast material with different scanner generations with automatic exposure control (AEC). Methods and materials: Each 42 adult patients received a NECT and CECT of the chest in one session on a 16-, 64- or 128-slice CT scanner with the same scan protocol settings. However, AEC technology (Care Dose 4D, Siemens) underwent upgrades in each of the three scanner generations. DLP, CTDIvol and image noise were compared. Results: Although absolute differences in image noise were very small and ranged between 10 and 13 HU for NECT and CECT in median, the differences in image noise and dose (DLP: 16-slice:+2.8%; 64-slice:+3.9%; 128-slice:+5.6%) between NECT and CECT were statistically significant in all groups. Image noise and dose parameters were significantly lower in the most recent 128-slice CT generation for both NECT and CECT (DLP: 16-slice:+35.5-39.2%; 64-slice:+6.8-8.5%). Conclusion: The presence of contrast material lead to an increase in dose for chest examinations in three CT generations with AEC. Although image noise values were significantly higher for CECT, the absolute differences were in a range of 3 HU. This can be regarded as negligible, thus indicating that AEC is able to fulfill its purpose of maintaining image quality. However, technological developments lead to a significant reduction of dose and image noise with the latest CT generation.

  11. Nasal airway epithelial cell IL-6 and FKBP51 gene expression and steroid sensitivity in asthmatic children.

    Directory of Open Access Journals (Sweden)

    Michael Fayon

    Full Text Available Many asthmatic patients exhibit uncontrolled asthma despite high-dose inhaled corticosteroids (ICS. Airway epithelial cells (AEC have distinct activation profiles that can influence ICS response.A pilot study to identify gene expression markers of AEC dysfunction and markers of corticosteroid sensitivity in asthmatic and non-asthmatic control children, for comparison with published reports in adults.AEC were obtained by nasal brushings and primary submerged cultures, and incubated in control conditions or in the presence of 10 ng/ml TNFalpha, 10-8M dexamethasone, or both. RT-PCR-based expression of FKBP51 (a steroid hormone receptor signalling regulator, NF-kB, IL-6, LIF (an IL-6 family neurotrophic cytokine, serpinB2 (which inhibits plasminogen activation and promotes fibrin deposition and porin (a marker of mitochondrial mass were determined.6 patients without asthma (median age 11yr; min-max: 7-13, 8 with controlled asthma (11yr, 7-13; median daily fluticasone dose = 100 μg, and 4 with uncontrolled asthma (12yr, 7-14; 1000 μg fluticasone daily were included. Baseline expression of LIF mRNA was significantly increased in uncontrolled vs controlled asthmatic children. TNFalpha significantly increased LIF expression in uncontrolled asthma. A similar trend was observed regarding IL-6. Dexamethasone significantly upregulated FKBP51 expression in all groups but the response was blunted in asthmatic children. No significant upregulation was identified regarding NF-kB, serpinB2 and porin.LIF and FKBP51 expression in epithelial cells were the most interesting markers of AEC dysfunction/response to corticosteroid treatment.

  12. ONEČIŠĆENJE MORA PLASTIČNIM OTPADOM

    OpenAIRE

    Kovač, Nikolina; Serdarušić, Ana

    2017-01-01

    Onečišćenje okoliša jedan je od najvećih problema s kojim se susreće današnje društvo. Iako se počelo sve više govoriti o zagađenju okoliša i koliko ono utječe kako na ljude, tako i na biljni i životinjski svijet, još nema dovoljne osviještenosti čovjeka o tom izuzetno bitnom problemu za našu budućnost. Iako postoje razna onečišćenja okoliša, mi ćemo se osvrnuti na onečišćenje mora. Do onečišćenja mora može doći na razne načine kao npr. otpadnim vodama, balastnim vodama, pogonskim uljima, naf...

  13. Copper(II) complexes of alloferon 1 with point mutations (H1A) and (H9A) stability structure and biological activity.

    Science.gov (United States)

    Matusiak, Agnieszka; Kuczer, Mariola; Czarniewska, Elżbieta; Rosiński, Grzegorz; Kowalik-Jankowska, Teresa

    2014-09-01

    Mono- and polynuclear copper(II) complexes of the alloferon 1 with point mutations (H1A) A(1)GVSGH(6)GQH(9)GVH(12)G (Allo1A) and (H9A) H(1)GVSGH(6)GQA(9)GVH(12)G (Allo9A) have been studied by potentiometric, UV-visible, CD, EPR spectroscopic and mass spectrometry (MS) methods. To obtain a complete complex speciation different metal-to-ligand molar ratios ranging from 1:1 to 4:1 for Allo1A and to 3:1 for Allo9A were studied. The presence of the His residue in first position of the peptide chain changes the coordination abilities of the Allo9A peptide in comparison to that of the Allo1A. Imidazole-N3 atom of N-terminal His residue of the Allo9A peptide forms stable 6-membered chelate with the terminal amino group. Furthermore, the presence of two additional histidine residues in the Allo9A peptide (H(6),H(12)) leads to the formation of the CuL complex with 4N {NH2,NIm-H(1),NIm-H(6),NIm-H(12)} binding site in wide pH range (5-8). For the Cu(II)-Allo1A system, the results demonstrated that at physiological pH7.4 the predominant complex the CuH-1L consists of the 3N {NH2,N(-),CO,NIm} coordination mode. The inductions of phenoloxidase activity and apoptosis in vivo in Tenebrio molitor cells by the ligands and their copper(II) complexes at pH7.4 were studied. The Allo1A, Allo1K peptides and their copper(II) complexes displayed the lowest hemocytotoxic activity while the most active was the Cu(II)-Allo9A complex formed at pH7.4. The results may suggest that the N-terminal-His(1) and His(6) residues may be more important for their proapoptotic properties in insects than those at positions 9 and 12 in the peptide chain. Copyright © 2014 Elsevier Inc. All rights reserved.

  14. Sotsiaalne kapital, poliitiliste institutsioonide mõjutamisvõimaluste tunnetamine ja usaldus võimuinstitutsioonide vastu / Tõnis Saarts

    Index Scriptorium Estoniae

    Saarts, Tõnis

    2002-01-01

    Autor vaatleb kuivõrd mõjutab sotsiaalne kapital ja poliitiliste institutsioonide töö mõjutamise võimaluse tunnetamine mitte-eestlaste ja eestlaste usaldust nende poliitiliste institutsioonide vastu nii kohalikul kui ka keskvõimu tasandil. Tabelid. Bibliogr. 8 nim. Kokkuvõte ingl. k.

  15. Kas õpilaste stress on viimase kümmekonna aastaga suurenenud? / Marit Tarkin, Enda Trubok, Kersti Rohtmets, Leena Arras, Kaie Lõhmus

    Index Scriptorium Estoniae

    2010-01-01

    Küsimusele vastavad Kuressaare gümnaasiumi õpetaja Marit Tarkin, Albu põhikooli õpetaja Enda Trubok, Audru keskkooli direktor Kersti Rohtmets, Tallinna Pääsküla gümnaasiumi direktor Leena Arras, C. R. Jakobsoni nim gümnaasiumi õppealajuhataja Kaie Lõhmus

  16. IAEA-HypoX. A randomized multicenter study of the hypoxic radiosensitizer nimorazole concomitant with accelerated radiotherapy in head and neck squamous cell carcinoma

    DEFF Research Database (Denmark)

    Metwally, Mohamed Ahmed Hassan; Ali, Rubina; Kuddu, Maire

    2015-01-01

    PURPOSE: To test the hypothesis that radiotherapy (RT) of head and neck squamous cell carcinoma (HNSCC) can be improved by hypoxic modification using nimorazole (NIM) in association with accelerated fractionation. MATERIALS AND METHODS: The protocol was activated in March 2012 as an international...

  17. Modeling recognition memory using the similarity structure of natural input

    NARCIS (Netherlands)

    Lacroix, J.P.W.; Murre, J.M.J.; Postma, E.O.; van den Herik, H.J.

    2006-01-01

    The natural input memory (NIM) model is a new model for recognition memory that operates on natural visual input. A biologically informed perceptual preprocessing method takes local samples (eye fixations) from a natural image and translates these into a feature-vector representation. During

  18. A TRIGA refueling exercise

    Energy Technology Data Exchange (ETDEWEB)

    McEwen, Michael J [Kansas State University (United States)

    1974-07-01

    In June 1973 the U.S. Atomic Energy Commission offered to assist the Department of Nuclear Engineering staff in refueling the KSU TRIGA Mkll - Nuclear Reactor. The replacement fuel was made available free of charge and a contract was negotiated between the Department of Nuclear Engineering and the A.E.C. to provide for costs incurred during the refueling operation. In addition, the A.E.C. aided in the fuel transfers by providing the names of contacts at the different laboratories and agencies concerned with fuel transfers. Data and numbers relevant to the entire reloading will be available in the short summary. (author)

  19. WINCO's experience with environmental compliance at 1950's vintage DOE nuclear facilities

    International Nuclear Information System (INIS)

    Porter, C.L.

    1992-01-01

    During the 1950's numerous nuclear facilities were built under the auspices of the Atomic Energy Commission (AEC). One such facility, a nuclear fuels reprocessing facility located in Idaho has operated over the past 40 years. In the late 1980's federal facilities became subject to the same environmental regulations as commercial facilities. Since the Department of Energy's mission called for continued reprocessing at the Idaho facility, compliance with current environmental standards became necessary. Certified compliance was achieved with a minimum of modifications by capitalizing upon existing building features that resulted from original AEC design criteria

  20. Solid oxide electrolysis cells - Performance and durability

    Energy Technology Data Exchange (ETDEWEB)

    Hauch, A.

    2007-10-15

    In this work H2 electrode supported solid oxide cells (SOC) produced at Risoe National Laboratory, DTU, have been used for steam electrolysis. Electrolysis tests have been performed at temperatures from 650AeC to 950AeC, p(H2O)/p(H2) from 0.99/0.01 to 0.30/0.70 and current densities from -0.25 A/cm2 to -2 A/cm2. The solid oxide electrolysis cells (SOEC) have been characterised by iV curves and electrochemical impedance spectroscopy (EIS) at start and end of tests and by EIS under current load during electrolysis testing. The tested SOCs have shown the best initial electrolysis performance reported in literature to date. Area specific resistances of 0.26 Oecm2 at 850AeC and 0.17 Oecm2 at 950AeC were obtained from electrolysis iV curves. The general trend for the SOEC tests was: 1) a short-term passivation in first few hundred hours, 2) then an activation and 3) a subsequent and underlying long-term degradation. The transient phenomenon (passivation/activation) was shown to be a set-up dependent artefact caused by the albite glass sealing with a p(Si(OH)4) of 1.10-7 atm, leading to silica contamination of the triple-phase boundaries (TPBs) of the electrode. The long-term degradation for the SOECs was more pronounced than for fuel cell testing of similar cells. Long-term degradation of 2%/1000 h was obtained at 850AeC, p(H2O)/p(H2) = 0.5/0.5 and -0.5 A/cm2, whereas the degradation rate increased to 6%/1000h at 950AeC, p(H2O)/p(H2) = 0.9/0.1 and -1.0 A/cm2. Both the short-term passivation and the long-term degradation appear mainly to be related to processes in the H2 electrode. Scanning electron microscopy micrographs show that only limited changes occur in the Ni particle size distribution and these are not the main degradation mechanism for the SOECs. Micro and nano analysis using energy dispersive spectroscopy in combination with transmission electron microscopy (TEM) and scanning TEM reveals that glassy phase impurities have accumulated at the TPBs as a result of

  1. Instrumentation for Nuclear Applications

    International Nuclear Information System (INIS)

    1998-01-01

    The objective of this project was to develop and coordinate nuclear instrumentation standards with resulting economies for the nuclear and radiation fields. There was particular emphasis on coordination and management of the Nuclear Instrument Module (NIM) System, U.S. activity involving the CAMAC international standard dataway system, the FASTBUS modular high-speed data acquisition and control system and processing and management of national nuclear instrumentation and detector standards, as well as a modest amount of assistance and consultation services to the Pollutant Characterization and Safety Research Division of the Office of Health and Environmental Research. The principal accomplishments were the development and maintenance of the NIM instrumentation system that is the predominant instrumentation system in the nuclear and radiation fields worldwide, the CAMAC digital interface system in coordination with the ESONE Committee of European Laboratories, the FASTBUS high-speed system and numerous national and international nuclear instrumentation standards

  2. Nanoscale Ionic Materials

    KAUST Repository

    Rodriguez, Robert; Herrera, Rafael; Archer, Lynden A.; Giannelis, Emmanuel P.

    2008-01-01

    Polymer nanocomposites (nanoparticles dispersed in a polymer matrix) have been the subject of intense research for almost two decades in both academic and industrial settings. This interest has been fueled by the ability of nanocomposites to not only improve the performance of polymers, but also by their ability to introduce new properties. Yet, there are still challenges that polymer nanocomposites must overcome to reach their full potential. In this Research News article we discuss a new class of hybrids termed nanoparticle ionic materials (NIMS). NIMS are organic-inorganic hybrid materials comprising a nanoparticle core functionalized with a covalently tethered ionic corona. They are facilely engineered to display flow properties that span the range from glassy solids to free flowing liquids. These new systems have unique properties that can overcome some of the challenges facing nanocomosite materials. © 2008 WILEY-VCH Verlag GmbH & Co. KGaA.

  3. A 75 ps rms time resolution BiCMOS time to digital converter optimized for high rate imaging detectors

    CERN Document Server

    Hervé, C

    2002-01-01

    This paper presents an integrated time to digital converter (TDC) with a bin size adjustable in the range of 125 to 175 ps and a differential nonlinearity of +-0.3%. The TDC has four channels. Its architecture has been optimized for the readout of imaging detectors in use at Synchrotron Radiation facilities. In particular, a built-in logic flags piled-up events. Multi-hit patterns are also supported for other applications. Time measurements are extracted off chip at the maximum throughput of 40 MHz. The dynamic range is 14 bits. It has been fabricated in 0.8 mu m BiCMOS technology. Time critical inputs are PECL compatible whereas other signals are CMOS compatible. A second application specific integrated circuit (ASIC) has been developed which translates NIM electrical levels to PECL ones. Both circuits are used to assemble board level TDCs complying with industry standards like VME, NIM and PCI.

  4. Nuclear timer/counter

    International Nuclear Information System (INIS)

    Wuthayavanich, S.

    1978-01-01

    This thesis represents the development of a Timer/COUNTER compatible to the standard Nuclear Instrument Module Specifications. The unit exhibits high accuracy, light weight and ease of maintenance. The unit also has a built-in precision discriminator to discriminate unwanted signals that may cause interference in counting. With line frequency time base the timer can be preset in steps from 0.1 sec. to 9 x 10 5 min. The counter with six digits miniature display and an overflow output has a maximum counting rate of 10 MHz. The accumulated counting data can be transferred to a teletype or printer for hard copy printout with the aid of ORTEC 777 Line Printer or 432 A Print-out Control or any print out interface with input compatible to the print output of the Timer/Counter. Owing to its NIM compatibility the unit is directly powered by the NIM power supply

  5. Quench tests of Nb3Al small racetrack magnets

    International Nuclear Information System (INIS)

    Yamada, R.; Kikuchi, A.; Tartaglia, Michael Albert; Ambrosio, G.; Andreev, N.; Barzi, E.; Carcagno, R.; Feher, S.; Kashikhin, V.V.; Kotelnikov, S.; Lamm, Michael J.; Fermilab; NIMC, Tsukuba; KEK, Tsukuba

    2007-01-01

    Two Cu stabilized Nb3Al strands, F1 (Nb matrixed) and F3 (Ta matrixed), have been made at NIMS and their Rutherford cables were made at Fermilab in collaboration with NIMS. A Small Race-track magnet using F1 Rutherford cable, the first Nb3Al dipole magnet in the world, was constructed and tested to full current at Fermilab. This magnet was tested extensively to full short sample data and its quench characteristics were studied and reported. The 3-D magnetic field calculation was done with ANSYS to find the peak field. The quench characteristics of the magnet are explained with the characteristics of the Nb3Al strand and Rutherford cable. The other Small Race-track magnet using Ta matrixed F3 strand was constructed and will be tested in the near future. The advantages and disadvantages of these Nb3Al cables are discussed

  6. Quench tests of Nb3Al small racetrack magnets

    Energy Technology Data Exchange (ETDEWEB)

    Yamada, R.; Kikuchi, A.; Tartaglia, Michael Albert; Ambrosio, G.; Andreev, N.; Barzi, E.; Carcagno, R.; Feher, S.; Kashikhin, V.V.; Kotelnikov, S.; Lamm, Michael J.; /Fermilab /NIMC, Tsukuba /KEK, Tsukuba

    2007-08-01

    Two Cu stabilized Nb3Al strands, F1 (Nb matrixed) and F3 (Ta matrixed), have been made at NIMS and their Rutherford cables were made at Fermilab in collaboration with NIMS. A Small Race-track magnet using F1 Rutherford cable, the first Nb3Al dipole magnet in the world, was constructed and tested to full current at Fermilab. This magnet was tested extensively to full short sample data and its quench characteristics were studied and reported. The 3-D magnetic field calculation was done with ANSYS to find the peak field. The quench characteristics of the magnet are explained with the characteristics of the Nb3Al strand and Rutherford cable. The other Small Race-track magnet using Ta matrixed F3 strand was constructed and will be tested in the near future. The advantages and disadvantages of these Nb3Al cables are discussed.

  7. Experience of monitoring the recurrent laryngeal nerve in thyroid surgery with endotracheal intubation

    Directory of Open Access Journals (Sweden)

    Liang Feng

    2017-01-01

    Full Text Available Purpose:To analysis clinical experience of applying recurrent laryngeal monitoring endotracheal tube (NIM EMG Endotracheal Tube in the surgery of thyroid. Method: A retrospective analysis of 84 patients who underwent endotracheal intubation laryngeal nerve monitoring by thyroid surgery in the Chinese-Japanese Friendship Hospital of Jilin University from March to December in 2015. To summarize the experience of intubation with NIM EMG Endotracheal Tube. Result 77 (91.7%had initial intubation achievement in the 84 patients.FROM the 77 cases we had gotten s atisfactory nerve monitoring signal.Whereas there are 7 cases (8.3% appear abnormal EMG or signal missing, in the 7 cases there is one which being intubated too deep, 3 cases which being intubated too shallow and 3 cases with malrotation intubation.Conclusion: We got the satisfactory signals after adjust1ing the tube by using the visual laryngoscope.

  8. PDAC-100 operations manual

    International Nuclear Information System (INIS)

    Slice, R.

    1985-05-01

    The Programmable Data Acquisition and Control (PDAC-100) system was designed to provide data acquisition and control functions for dedicated in-plant nuclear safeguards systems. The PDAC-100, along with a detector, peripherals, and input/output devices, functions as a programmable multichannel analyzer, controls devices, acquires data, analyzes the results, and displays computed values. The PDAC-100 is packaged as a six-wide nuclear instrumentation module (NIM). The NIM standard allows the flexibility to use the optimum signal conditioning, analog-to-digital conversion, and stabilization electronics required for the specific application. The PDAC-100 uses a Motorola MC6802 microprocessor that executes a program stored in read-only memory. The program can be written in Motorola 6800 assembly, FORTRAN IV, or BASIC language. As an analyzer, the PDAC-100 uses an external analog-to-digital converter and an XYZ oscilloscope to acquire and display spectra of 1024 channels

  9. Nanoscale Ionic Materials

    KAUST Repository

    Rodriguez, Robert

    2008-11-18

    Polymer nanocomposites (nanoparticles dispersed in a polymer matrix) have been the subject of intense research for almost two decades in both academic and industrial settings. This interest has been fueled by the ability of nanocomposites to not only improve the performance of polymers, but also by their ability to introduce new properties. Yet, there are still challenges that polymer nanocomposites must overcome to reach their full potential. In this Research News article we discuss a new class of hybrids termed nanoparticle ionic materials (NIMS). NIMS are organic-inorganic hybrid materials comprising a nanoparticle core functionalized with a covalently tethered ionic corona. They are facilely engineered to display flow properties that span the range from glassy solids to free flowing liquids. These new systems have unique properties that can overcome some of the challenges facing nanocomosite materials. © 2008 WILEY-VCH Verlag GmbH & Co. KGaA.

  10. Antimicrobial resistance and prevalence of resistance genes of obligate anaerobes isolated from periodontal abscesses.

    Science.gov (United States)

    Xie, Yi; Chen, Jiazhen; He, Junlin; Miao, Xinyu; Xu, Meng; Wu, Xingwen; Xu, Beiyun; Yu, Liying; Zhang, Wenhong

    2014-02-01

    This study attempts to determine the antimicrobial resistance profiles of obligate anaerobic bacteria that were isolated from a periodontal abscess and to evaluate the prevalence of resistance genes in these bacteria. Forty-one periodontal abscess samples were cultivated on selective and non-selective culture media to isolate the oral anaerobes. Their antibiotic susceptibilities to clindamycin, doxycycline, amoxicillin, imipenem, cefradine, cefixime, roxithromycin, and metronidazole were determined using the agar dilution method, and polymerase chain reaction assays were performed to detect the presence of the ermF, tetQ, nim, and cfxA drug resistance genes. A total of 60 different bacterial colonies was isolated and identified. All of the isolates were sensitive to imipenem. Of the strains, 6.7%, 13.3%, 16.7%, and 25% were resistant to doxycycline, metronidazole, cefixime, and amoxicillin, respectively. The resistance rate for both clindamycin and roxithromycin was 31.7%. Approximately 60.7% of the strains had the ermF gene, and 53.3% of the amoxicillin-resistant strains were found to have the cfxA gene. Two nim genes that were found in eight metronidazole-resistant strains were identified as nimB. In the present study, the Prevotella species are the most frequently isolated obligate anaerobes from periodontal abscesses. The current results show their alarmingly high resistance rate against clindamycin and roxithromycin; thus, the use of these antibiotics is unacceptable for the empirical therapy of periodontal abscesses. A brief prevalence of four resistance genes in the anaerobic bacteria that were isolated was also demonstrated.

  11. Very-short range forecasting system for 2018 Pyeonchang Winter Olympic and Paralympic games

    Science.gov (United States)

    Nam, Ji-Eun; Park, Kyungjeen; Kim, Minyou; Kim, Changhwan; Joo, Sangwon

    2016-04-01

    The 23rd Olympic Winter and the 13th Paralympic Winter Games will be held in Pyeongchang, Republic of Korea respectively from 9 to 25 February 2018 and from 9 to 18 February 2018. The Korea Meteorological Administration (KMA) and the National Institute for Meteorological Science (NIMS) have the responsibility to provide weather information for the management of the Games and the safety of the public. NIMS will carry out a Forecast Demonstration Project (FDP) and a Research and Development Project (RDP) which will be called ICE-POP 2018. These projects will focus on intensive observation campaigns to understand severe winter weathers over the Pyeongchang region, and the research results from the RDP will be used to improve the accuracy of nowcasting and very short-range forecast systems during the Games. To support these projects, NIMS developed Very-short range Data Assimilation and Prediction System (VDAPS), which is run in real time with 1 hour cycling interval and up to 12 hour forecasts. The domain is covering Korean Peninsular and surrounding seas with 1.5km horizontal resolution. AWS, windprofiler, buoy, sonde, aircraft, scatwinds, and radar radial winds are assimilated by 3DVAR on 3km resolution inner domain. The rain rate is converted into latent heat and initialized via nudging. The visibility data are also assimilated with the addition of aerosol control variable. The experiments results show the improvement in rainfall over south sea of Korean peninsula. In order to reduce excessive rainfalls during first 2 hours due to the reduced cycling interval, the data assimilation algorithm is optimized.

  12. 76 FR 72431 - Criteria for Preparation and Evaluation of Radiological Emergency Response Plans and Preparedness...

    Science.gov (United States)

    2011-11-23

    ... national preparedness terms and concepts found in the National Incident Management System (NIMS)/ Incident... many of the REP Program's operative guidance and policy documents into one location, and [[Page 72432... for alert and notification systems. In addition, Supplement 4 revises and adds evaluation criteria and...

  13. The optimization of low-dose scanning protocols of 64-slice spiral CT in the adult chest: a multicenter study

    International Nuclear Information System (INIS)

    Tang Wei; Huang Yao; Wu Ning

    2011-01-01

    Objective: To compare the image quality of chest low dose CT (LDCT) using automatic exposure control (AEC) and constant current. control (CCC) and explore a more reasonable scanning protocol. Methods: Two hundred and eighty participants were examined with 64 CT scanner at 7 centers in China. All were divided into 4 groups. Two groups underwent LDCT using AEC with standard deviation set at 25 (Al) and 30 (A2) respectively and the tube current ranged from 10 mA to 80 mA. The other two groups underwent LDCT using CCC with tube current set at 40 mA (Cl) and 50 mA (C2) respectively. The axial and MPR images were evaluated by two radiologists who were blinded to the scanning protocols. The radiation dose, noise and the image quality of the 4 groups were compared and analyzed statistically. Differences of radiation dose and noise among groups were determined with variance analysis and t test, image quality with Mann- Whitney test and the consistency of diagnosis with Kappa test. Results: There was a significant lower DLP in AEC group than in CCC group [(82.62±40.31) vs (110.81±18.21) mGy · cm (F=56.88, P 0.05]. The noisy of AEC group was higher than that of CCC group both on lung window (41.50±9.58 vs 40.86±7.03) and mediastinum window (41.19±7.83 vs 40.92±9.89), but there was no significant difference (F lung =0.835, P=0.476, F wediastinum =1.910, P=0.128). The quality score of axial image in AEC group was higher than that in CCC group (superior margin of the brachiocephalic vein level: 4.49± 0.56 vs 4.38±0.64, superior margin of the aortic arch: 4.86±0.23 vs 4.81±0.32, the right superior lobar bronchus Level: 4.87±0.27 vs 4.84±0.22, the right middle lobar bronchus Level: 4.90±0.25 vs 4.88±0.21) except on the right inferior pulmonary vein level (4.92±0.25 vs 4.93±0.17) and superior margin of the left diaphragmatic dome level (4.91±0.27 vs 4.93±0.22) on lung window, but no significant differences (F=0.076-1.748, P>0.05) were observed. A significant

  14. Regulatory System of Radiation Protection in Taiwan

    International Nuclear Information System (INIS)

    Tang, F. T.; Huang, C. C.

    2004-01-01

    After the radioactive contaminated buildings incident occurred in Taiwan in 1993, the competent authority for radiation protection the Atomic Energy Council (AEC) started to review the structured problem of radiation protection regulatory system. Through several years' investigation and study, the AEC has improved two important tools in radiation protection regulatory system, i.e., control regulations and actual practice, and made them more rigorous and efficient. This paper will make a brief introduction of the efforts that Taiwan has made in this respect. Taiwan's radiation protection control was based on the Atomic Energy Law promulgated in 1968, but the control idea and authorization scope were not sufficient to appropriately respond to the highly developed economy and democracy in Taiwan. After several years' legislative process, the Ionizing Radiation Protection Law (IRP Law) was promulgated and entered into force on February 1, 2003. This IRP Law specifically emphasizes categorized risk management of radiation sources, establishment of personnel licenses and training system, enhancement of public safety control, and implementation of quality assurance program for medical exposure. The Legislative Yuan (Congress) fully authorized the competent authority to establish various technological control regulations according to control necessity without prior review by the Legislative Yuan in advance. As to the penalties of the violations of the IRP Law, the AEC adopts high-rated administrative fines and applies the Criminal Law to those who seriously contaminate the environment. In actual practice, the AEC has constructed a Radiation Protection Control Information System compatible with the IRP Law that fully combines the functions of computers and Internet. The information of facility operators who own radiation sources, radiation protection specialists, and operating personnel are entered into this system, starting from the submission of application of the

  15. Effect of automatic exposure control marker with chest radiography in radiation reduction

    International Nuclear Information System (INIS)

    Jung, Ji Sang; Choi, Byoung Wook; Shim, Ji Na; Ahn, Ho Sik; Jin, Duk Eun; Liml, Jae Sik; Kang, Sung Ho; Kim, Sung Ho; Kim, Young Mo

    2014-01-01

    This study focused on effects of patient exposure dose reduction with AEC (Auto Exposure Control) marker that is designed for showing location of AEC in X-ray Chest radiography. It included 880 adults who have to use Chest X-ray Digital Radiography system (DRS, LISTEM, Korea). AEC (Ion chambers are posited in top of both sides) are used to every adult and set X-ray system as Field size 17 x 17 inch, 120 kVp, FFD 180 cm. 440 people of control group are posited on detector to include both sides of lung field and the other 440 people of experimental group are set to contact their lung directly to Ion chamber (making marker to shows location). Then, measured every DAP and, estimated patient effective dose by using PCXMC 2.0. The average age of control group (M:F=245:195) is 53.9 and the average BMI is 23.4. BMI ranges from under weight: 35, normal range: 279, over weight: 106 to obese: 20 and average DAP is 223.56 mGycm2, Mean effective dose is 0.045 mSv. The average age of experimental group (M:F=197:243) is 53.7 and the average BMI is 22.7. BMI ranges from under weight: 34, normal range: 315, over weight: 85 to obese: 6 and average DAP is 207.36 mGycm2, Mean effective dose is 0.041 mSv. Experimental group shows less Mean effective dose as 0.004mSv (9.7%) than control group. Also, patient numbers who got over exposure more than 0.056 mSv (limit point to know efficiency of AEC marker) is 65 in control group(14.7%), 19 in experimental group (4.3%) and take statistics with t-Test. The statistical difference between two groups is 0.006. In order to use proper amount of X-ray in auto exposure controlled chest X-ray system, matching location between ion chamber and body part is needed, and using AEC marker (designed for showing location of ion chamber) is a way to reduce unnecessary patient exposure dose

  16. Effect of automatic exposure control marker with chest radiography in radiation reduction

    Energy Technology Data Exchange (ETDEWEB)

    Jung, Ji Sang; Choi, Byoung Wook; Shim, Ji Na; Ahn, Ho Sik; Jin, Duk Eun; Liml, Jae Sik; Kang, Sung Ho [Severance Hospital, Yonsei University College of Medicine, Seoul (Korea, Republic of); Kim, Sung Ho [LISTEM, Woonju (Korea, Republic of); Kim, Young Mo [Dept. of Biomedical Engineering, Konyang University, Nonsan (Korea, Republic of)

    2014-09-15

    This study focused on effects of patient exposure dose reduction with AEC (Auto Exposure Control) marker that is designed for showing location of AEC in X-ray Chest radiography. It included 880 adults who have to use Chest X-ray Digital Radiography system (DRS, LISTEM, Korea). AEC (Ion chambers are posited in top of both sides) are used to every adult and set X-ray system as Field size 17 x 17 inch, 120 kVp, FFD 180 cm. 440 people of control group are posited on detector to include both sides of lung field and the other 440 people of experimental group are set to contact their lung directly to Ion chamber (making marker to shows location). Then, measured every DAP and, estimated patient effective dose by using PCXMC 2.0. The average age of control group (M:F=245:195) is 53.9 and the average BMI is 23.4. BMI ranges from under weight: 35, normal range: 279, over weight: 106 to obese: 20 and average DAP is 223.56 mGycm2, Mean effective dose is 0.045 mSv. The average age of experimental group (M:F=197:243) is 53.7 and the average BMI is 22.7. BMI ranges from under weight: 34, normal range: 315, over weight: 85 to obese: 6 and average DAP is 207.36 mGycm2, Mean effective dose is 0.041 mSv. Experimental group shows less Mean effective dose as 0.004mSv (9.7%) than control group. Also, patient numbers who got over exposure more than 0.056 mSv (limit point to know efficiency of AEC marker) is 65 in control group(14.7%), 19 in experimental group (4.3%) and take statistics with t-Test. The statistical difference between two groups is 0.006. In order to use proper amount of X-ray in auto exposure controlled chest X-ray system, matching location between ion chamber and body part is needed, and using AEC marker (designed for showing location of ion chamber) is a way to reduce unnecessary patient exposure dose.

  17. Lung fibroblasts accelerate wound closure in human alveolar epithelial cells through hepatocyte growth factor/c-Met signaling.

    Science.gov (United States)

    Ito, Yoko; Correll, Kelly; Schiel, John A; Finigan, Jay H; Prekeris, Rytis; Mason, Robert J

    2014-07-01

    There are 190,600 cases of acute lung injury/acute respiratory distress syndrome (ALI/ARDS) each year in the United States, and the incidence and mortality of ALI/ARDS increase dramatically with age. Patients with ALI/ARDS have alveolar epithelial injury, which may be worsened by high-pressure mechanical ventilation. Alveolar type II (ATII) cells are the progenitor cells for the alveolar epithelium and are required to reestablish the alveolar epithelium during the recovery process from ALI/ARDS. Lung fibroblasts (FBs) migrate and proliferate early after lung injury and likely are an important source of growth factors for epithelial repair. However, how lung FBs affect epithelial wound healing in the human adult lung has not been investigated in detail. Hepatocyte growth factor (HGF) is known to be released mainly from FBs and to stimulate both migration and proliferation of primary rat ATII cells. HGF is also increased in lung tissue, bronchoalveolar lavage fluid, and serum in patients with ALI/ARDS. Therefore, we hypothesized that HGF secreted by FBs would enhance wound closure in alveolar epithelial cells (AECs). Wound closure was measured using a scratch wound-healing assay in primary human AEC monolayers and in a coculture system with FBs. We found that wound closure was accelerated by FBs mainly through HGF/c-Met signaling. HGF also restored impaired wound healing in AECs from the elderly subjects and after exposure to cyclic stretch. We conclude that HGF is the critical factor released from FBs to close wounds in human AEC monolayers and suggest that HGF is a potential strategy for hastening alveolar repair in patients with ALI/ARDS. Copyright © 2014 the American Physiological Society.

  18. MUSYARAKAH FINANCE PROSPECT IN ISLAMIC BANK IN THE FACE OF ASEAN ECONOMIC COMMUNITY (MEA

    Directory of Open Access Journals (Sweden)

    Ahmad Supriyadi

    2016-11-01

    Full Text Available In the era of Dutch colonial, the majority of entrepreneurs in Central Java and Yogyakarta come from the students. But after Indonesian independence, the students did not show up in the business world because of political policy. Nowadays the entrepreneur students bounced back with Islamic banks that one of its products is a Musharakah finance. Musharakah finance deal with the birth of the free market, namely the ASEAN Economic Community so that the question arises how the prospect Musharakah finance in Indonesian Islamic banks of facing the ASEAN Economic Community (AEC. This paper aims to describe the prospect of Musharakah finance to face AEC. The results showed that the Musharakah finance has a lot of prospects such as financing products that can be performed well and have a competitive value because it has a solid legal basis. From the network side, Islamic banks have been supported by a network offices that much better at home and abroad with excellent quality customer service. In addition, the presence Bank Indonesia blueprint of the Islamic banking institution can strengthen the Musharakah finance products so that can be applied in the ASEAN Economic Community (AEC.

  19. Nerve signaling regulates basal keratinocyte proliferation in the blastema apical epithelial cap in the axolotl (Ambystoma mexicanum).

    Science.gov (United States)

    Satoh, Akira; Bryant, Susan V; Gardiner, David M

    2012-06-15

    The ability of adult vertebrates to repair tissue damage is widespread and impressive; however, the ability to regenerate structurally complex organs such as the limb is limited largely to the salamanders. The fact that most of the tissues of the limb can regenerate has led investigators to question and identify the barriers to organ regeneration. From studies in the salamander, it is known that one of the earliest steps required for successful regeneration involves signaling between nerves and the wound epithelium/apical epithelial cap (AEC). In this study we confirm an earlier report that the keratinocytes of the AEC acquire their function coincident with exiting the cell cycle. We have discovered that this unique, coordinated behavior is regulated by nerve signaling and is associated with the presence of gap junctions between the basal keratinocytes of the AEC. Disruption of nerve signaling results in a loss of gap junction protein, the reentry of the cells into the cell cycle, and regenerative failure. Finally, coordinated exit from the cell cycle appears to be a conserved behavior of populations of cells that function as signaling centers during both development and regeneration. Copyright © 2012 Elsevier Inc. All rights reserved.

  20. Final report of the decontamination and decommissioning of the exterior land areas at the Grand Junction Projects Office facility

    Energy Technology Data Exchange (ETDEWEB)

    Widdop, M.R.

    1995-09-01

    The US Department of Energy (DOE) Grand Junction Projects Office (GJPO) facility occupies approximately 56.4 acres (22.8 hectares) along the Gunnison River near Grand Junction, Colorado. The site was contaminated with uranium ore and mill tailings during uranium-refining activities conducted by the Manhattan Engineer District and during pilot-milling experiments conducted for the US Atomic Energy Commission`s (AEC`s) domestic uranium procurement program. The GJPO facility was the collection and assay point for AEC uranium and vanadium oxide purchases until the early 1970s. The DOE Decontamination and Decommissioning Program sponsored the Grand Junction Projects Office Remedial Action Project (GJPORAP) to remediate the facility lands, site improvements, and the underlying aquifer. The site contractor, Rust Geotech, was the Remedial Action Contractor for GJPORAP. The exterior land areas of the facility assessed as contaminated have been remediated in accordance with identified standards and can be released for unrestricted use. Restoration of the aquifer will be accomplished through the natural flushing action of the aquifer during the next 50 to 80 years. The remediation of the DOE-GJPO facility buildings is ongoing and will be described in a separate report.