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Sample records for advanced study institute

  1. NATO Advanced Study Institute on Advanced Physical Oceanographic Numerical Modelling

    CERN Document Server

    1986-01-01

    This book is a direct result of the NATO Advanced Study Institute held in Banyuls-sur-mer, France, June 1985. The Institute had the same title as this book. It was held at Laboratoire Arago. Eighty lecturers and students from almost all NATO countries attended. The purpose was to review the state of the art of physical oceanographic numerical modelling including the parameterization of physical processes. This book represents a cross-section of the lectures presented at the ASI. It covers elementary mathematical aspects through large scale practical aspects of ocean circulation calculations. It does not encompass every facet of the science of oceanographic modelling. We have, however, captured most of the essence of mesoscale and large-scale ocean modelling for blue water and shallow seas. There have been considerable advances in modelling coastal circulation which are not included. The methods section does not include important material on phase and group velocity errors, selection of grid structures, advanc...

  2. NATO Advanced Study Institute on Advances in Chemical Reaction Dynamics

    CERN Document Server

    Capellos, Christos

    1986-01-01

    This book contains the formal lectures and contributed papers presented at the NATO Advanced Study Institute on. the Advances in Chemical Reaction Dynamics. The meeting convened at the city of Iraklion, Crete, Greece on 25 August 1985 and continued to 7 September 1985. The material presented describes the fundamental and recent advances in experimental and theoretical aspects of, reaction dynamics. A large section is devoted to electronically excited states, ionic species, and free radicals, relevant to chemical sys­ tems. In addition recent advances in gas phase polymerization, formation of clusters, and energy release processes in energetic materials were presented. Selected papers deal with topics such as the dynamics of electric field effects in low polar solutions, high electric field perturbations and relaxation of dipole equilibria, correlation in picosecond/laser pulse scattering, and applications to fast reaction dynamics. Picosecond transient Raman spectroscopy which has been used for the elucidati...

  3. NATO Advanced Study Institute on Superconducting Electronics

    CERN Document Server

    Nisenhoff, Martin; Superconducting Electronics

    1989-01-01

    The genesis of the NATO Advanced Study Institute (ASI) upon which this volume is based, occurred during the summer of 1986 when we came to the realization that there had been significant progress during the early 1980's in the field of superconducting electronics and in applications of this technology. Despite this progress, there was a perception among many engineers and scientists that, with the possible exception of a limited number of esoteric fundamental studies and applications (e.g., the Josephson voltage standard or the SQUID magnetometer), there was no significant future for electronic systems incorporating superconducting elements. One of the major reasons for this perception was the aversion to handling liquid helium or including a closed-cycle helium liquefier. In addition, many critics felt that IBM's cancellation of its superconducting computer project in 1983 was "proof" that superconductors could not possibly compete with semiconductors in high-speed signal processing. From our persp...

  4. NATO Advanced Study Institute on Metal Hydrides

    CERN Document Server

    1981-01-01

    In the last five years, the study of metal hydrides has ex­ panded enormously due to the potential technological importance of this class of materials in hydrogen based energy conversion schemes. The scope of this activity has been worldwide among the industrially advanced nations. There has been a consensus among researchers in both fundamental and applied areas that a more basic understanding of the properties of metal/hydrogen syster;,s is required in order to provide a rational basis for the selection of materials for specific applications. The current worldwide need for and interest in research in metal hydrides indicated the timeliness of an Advanced Study Insti­ tute to provide an in-depth view of the field for those active in its various aspects. The inclusion of speakers from non-NATO coun­ tries provided the opportunity for cross-fertilization of ideas for future research. While the emphasis of the Institute was on basic properties, there was a conscious effort to stimulate interest in the applic...

  5. NATO Advanced Study Institute on Nanotechnological Basis for Advanced Sensors

    CERN Document Server

    Reithmaier, Johann Peter; Kulisch, Wilhelm; Popov, Cyril; Petkov, Plamen

    2011-01-01

    Bringing together experts from 15 countries, this book is based on the lectures and contributions of the NATO Advanced Study Institute on “Nanotechnological Basis for Advanced Sensors” held in Sozopol, Bulgaria, 30 May - 11 June, 2010. It gives a broad overview on this topic, and includes articles on: techniques for preparation and characterization of sensor materials; different types of nanoscaled materials for sensor applications, addressing both their structure (nanoparticles, nanocomposites, nanostructured films, etc.) and chemical nature (carbon-based, oxides, glasses, etc.); and on advanced sensors that exploit nanoscience and nanotechnology. In addition, the volume represents an interdisciplinary approach with authors coming from diverse fields such as physics, chemistry, engineering, materials science and biology. A particular strength of the book is its combination of longer papers, introducing the basic knowledge on a certain topic, and brief contributions highlighting special types of sensors a...

  6. NATO Advanced Study Institute on Advances in Microlocal Analysis

    CERN Document Server

    1986-01-01

    The 1985 Castel vecchio-Pas coli NATO Advanced Study Institute is aimed to complete the trilogy with the two former institutes I organized : "Boundary Value Problem for Evolution Partial Differential Operators", Liege, 1976 and "Singularities in Boundary Value Problems", Maratea, 1980. It was indeed necessary to record the considerable progress realized in the field of the propagation of singularities of Schwartz Distri­ butions which led recently to the birth of a new branch of Mathema­ tical Analysis called Microlocal Analysis. Most of this theory was mainly built to be applied to distribution solutions of linear partial differential problems. A large part of this institute still went in this direction. But, on the other hand, it was also time to explore the new trend to use microlocal analysis In non linear differential problems. I hope that the Castelvecchio NATO ASI reached its purposes with the help of the more famous authorities in the field. The meeting was held in Tuscany (Italy) at Castelvecchio-P...

  7. NATO Advanced Study Institute on Quantum Magnetism

    CERN Document Server

    Barbara, Bernard; Sawatzky, G; Stamp, P. C. E

    2008-01-01

    This book is based on some of the lectures during the Pacific Institute of Theoretical Physics (PITP) summer school on "Quantum Magnetism", held during June 2006 in Les Houches, in the French Alps. The school was funded jointly by NATO, the CNRS, and PITP, and entirely organized by PITP. Magnetism is a somewhat peculiar research field. It clearly has a quantum-mechanical basis – the microsopic exchange interactions arise entirely from the exclusion principle, in conjunction with respulsive interactions between electrons. And yet until recently the vast majority of magnetism researchers and users of magnetic phenomena around the world paid no attention to these quantum-mechanical roots. Thus, eg., the huge ($400 billion per annum) industry which manufactures hard discs, and other components in the information technology sector, depends entirely on room-temperature properties of magnets - yet at the macroscopic or mesoscopic scales of interest to this industry, room-temperature magnets behave entirely classic...

  8. NATO Advanced Study Institute on Electron Crystallography

    CERN Document Server

    Weirich, Thomas E; Zou, Xiaodong

    2006-01-01

    During the last decade we have been witness to several exciting achievements in electron crystallography. This includes structural and charge density studies on organic molecules complicated inorganic and metallic materials in the amorphous, nano-, meso- and quasi-crystalline state and also development of new software, tailor-made for the special needs of electron crystallography. Moreover, these developments have been accompanied by a now available new generation of computer controlled electron microscopes equipped with high-coherent field-emission sources, cryo-specimen holders, ultra-fast CCD cameras, imaging plates, energy filters and even correctors for electron optical distortions. Thus, a fast and semi-automatic data acquisition from small sample areas, similar to what we today know from imaging plates diffraction systems in X-ray crystallography, can be envisioned for the very near future. This progress clearly shows that the contribution of electron crystallography is quite unique, as it enables to r...

  9. NATO Advanced Study Institute on Methods in Computational Molecular Physics

    CERN Document Server

    Diercksen, Geerd

    1992-01-01

    This volume records the lectures given at a NATO Advanced Study Institute on Methods in Computational Molecular Physics held in Bad Windsheim, Germany, from 22nd July until 2nd. August, 1991. This NATO Advanced Study Institute sought to bridge the quite considerable gap which exist between the presentation of molecular electronic structure theory found in contemporary monographs such as, for example, McWeeny's Methods 0/ Molecular Quantum Mechanics (Academic Press, London, 1989) or Wilson's Electron correlation in moleeules (Clarendon Press, Oxford, 1984) and the realization of the sophisticated computational algorithms required for their practical application. It sought to underline the relation between the electronic structure problem and the study of nuc1ear motion. Software for performing molecular electronic structure calculations is now being applied in an increasingly wide range of fields in both the academic and the commercial sectors. Numerous applications are reported in areas as diverse as catalysi...

  10. From "fixing women" to "institutional transformation": An ADVANCE case study

    Science.gov (United States)

    Yennello, Sherry; Kaunas, Christine

    2015-12-01

    The United States' position in the global economy requires an influx of women into science, technology, engineering, and mathematics (STEM) fields in order to remain competitive. Despite this, the representation of women in STEM continues to be low. The National Science Foundation's ADVANCE Program addresses this issue by funding projects that aim to increase the representation of women in academic STEM fields through transformation of institutional structures that impede women's progress in academic STEM fields. This paper includes a case study of the Texas A&M University ADVANCE Program.

  11. NATO Advanced Study Institute on Physics of New Laser Sources

    CERN Document Server

    Arecchi, F; Mooradian, Aram; Sona, Alberto

    1985-01-01

    This volume contains the lectures and seminars presented at the NATO Advanced Study Institute on "Physics of New Laser Sources", the twelfth course of the Europhysics School of Quantum Electronics, held under the supervision of the Quantum Electronics Division of the European Physical Society. The Institute was held at Centro "I Cappuccini" San Miniato, Tuscany, July 11-21, 1984. The Europhysics School of Quantum Electronics was started in 1970 with the aim of providing instruction for young researchers and advanced students already engaged in the area of quantum electronics or for those wishing to switch into this area after working previously in other areas. From the outset, the School has been under the direction of Prof. F. T. Arecchi, then at the University of Pavia, now at the University of Florence, and Dr. D. Roess of Heraeus, Hanau. In 1981, Prof. H. Walther, University of Munich and Max-Planck Institut fur Quantenoptik joined as co-director. Each year the Directors choose a subj~ct of particular int...

  12. NATO Advanced Study Institute on Nonequilibrium Phonon Dynamics

    CERN Document Server

    1985-01-01

    Phonons are always present in the solid state even at an absolute temperature of 0 K where zero point vibrations still abound. Moreover, phonons interact with all other excitations of the solid state and, thereby, influence most of its properties. Historically experimental information on phonon transport came from measurements of thermal conductivity. Over the past two decades much more, and much more detailed, information on phonon transport and on many of the inherent phonon interaction processes have come to light from experiments which use nonequilibrium phonons to study their dynamics. The resultant research field has most recently blossomed with the development of ever more sophisticated experimental and theoretical methods which can be applied to it. In fact, the field is moving so rapidly that new members of the research community have difficulties in keeping up to date. This NATO Advanced Study Institute (ASI) was organized with the objective of overcoming the information barrier between those expert...

  13. NATO Advanced Study Institute on Hamiltonian Dynamical Systems and Applications

    CERN Document Server

    2008-01-01

    Physical laws are for the most part expressed in terms of differential equations, and natural classes of these are in the form of conservation laws or of problems of the calculus of variations for an action functional. These problems can generally be posed as Hamiltonian systems, whether dynamical systems on finite dimensional phase space as in classical mechanics, or partial differential equations (PDE) which are naturally of infinitely many degrees of freedom. This volume is the collected and extended notes from the lectures on Hamiltonian dynamical systems and their applications that were given at the NATO Advanced Study Institute in Montreal in 2007. Many aspects of the modern theory of the subject were covered at this event, including low dimensional problems as well as the theory of Hamiltonian systems in infinite dimensional phase space; these are described in depth in this volume. Applications are also presented to several important areas of research, including problems in classical mechanics, continu...

  14. NATO Advanced Study Institute on Atoms in Strong Fields

    CERN Document Server

    Clark, Charles; Nayfeh, Munir

    1990-01-01

    This book collects the lectures given at the NATO Advanced Study Institute on "Atoms in Strong Fields", which took place on the island of Kos, Greece, during the two weeks of October 9-21,1988. The designation "strong field" applies here to an external electromagnetic field that is sufficiently strong to cause highly nonlinear alterations in atomic or molecular struc­ ture and dynamics. The specific topics treated in this volume fall into two general cater­ gories, which are those for which strong field effects can be studied in detail in terrestrial laboratories: the dynamics of excited states in static or quasi-static electric and magnetic fields; and the interaction of atoms and molecules with intense laser radiation. In both areas there exist promising opportunities for research of a fundamental nature. An electric field of even a few volts per centimeter can be very strong on the atom­ ic scale, if it acts upon a weakly bound state. The study of Rydberg states with high reso­ lution laser spectroscop...

  15. NATO Advanced Study Institute on Chemical Transport in Melasomatic Processes

    CERN Document Server

    1987-01-01

    As indicated on the title page, this book is an outgrowth of the NATO Advanced Study Institute (ASI) on Chemical Transport in Metasomatic Processes, which was held in Greece, June 3-16, 1985. The ASI consisted of five days of invited lectures, poster sessions, and discussion at the Club Poseidon near Loutraki, Corinthia, followed by a two-day field trip in Corinthia and Attica. The second week of the ASI consisted of an excursion aboard M/S Zeus, M/Y Dimitrios II, and the M/S Irini to four of the Cycladic Islands to visit, study, and sample outstanding exposures of metasomatic activity on Syros, Siphnos, Seriphos, and Naxos. Nine­ teen invited lectures and 10 session chairmen/discussion leaders participated in the ASI, which was attended by a total of 92 professional scientists and graduate stu­ dents from 15 countries. Seventeen of the invited lectures and the Field Excursion Guide are included in this volume, together with 10 papers and six abstracts representing contributed poster sessions. Although more...

  16. NATO Advanced Study Institute on Turbulence, Weak and Strong

    CERN Document Server

    Cardoso, O

    1994-01-01

    The present volume comprises the contributions of some of the participants of the NATO Advance Studies Institute "Turbulence, Weak and Strong", held in Cargese, in August 1994. More than 70 scientists, from seniors to young students, have joined to­ gether to discuss and review new (and not so new) ideas and developments in the study of turbulence. One of the objectives of the School was to incorporate, in the same meeting, two aspects of turbulence, which are obviously linked, and which are often treated sep­ arately: fully developed turbulence (in two and three dimensions) and weak turbulence (essentially one and two-dimensional systems). The idea of preparing a dictionary rather than ordinary proceedings started from the feeling that the terminology of turbulence includes many long, technical, poorly evocative words, which are usually not understood by people exterior to the field, and which might be worth explaining. Students who start working in the field of turbulence face a sort of curious situation:...

  17. NATO Advanced Study Institute on Insurance and Risk Theory

    CERN Document Server

    Vylder, F; Haezendonck, J

    1986-01-01

    Canadian financial institutions have been in rapid change in the past five years. In response to these changes, the Department of Finance issued a discussion paper: The Regulation of Canadian Financial Institutions, in April 1985, and the government intends to introduce legislation in the fall. This paper studi.es the combinantion of financial institutions from the viewpoint of ruin probability. In risk theory developed to describe insurance companies [1,2,3,4,5J, the ruin probability of a company with initial reserve (capital) u is 6 1 -:;-7;;f3 u 1jJ(u) = H6 e H6 (1) Here,we assume that claims arrive as a Poisson process, and the claim amount is distributed as exponential distribution with expectation liS. 6 is the loading, i.e., premium charged is (1+6) times expected claims. Financial institutions are treated as "insurance companies": the difference between interest charged and interest paid is regarded as premiums, loan defaults are treated as claims.

  18. NATO Advanced Study Institute on Low Temperature Molecular Spectroscopy

    CERN Document Server

    1996-01-01

    Molecular spectroscopy has achieved rapid and significant progress in recent years, the low temperature techniques in particular having proved very useful for the study of reactive species, phase transitions, molecular clusters and crystals, superconductors and semiconductors, biochemical systems, astrophysical problems, etc. The widening range of applications has been accompanied by significant improvements in experimental methods, and low temperature molecular spectroscopy has been revealed as the best technique, in many cases, to establish the connection between experiment and theoretical calculations. This, in turn, has led to a rapidly increasing ability to predict molecular spectroscopic properties. The combination of an advanced tutorial standpoint with an emphasis on recent advances and new perspectives in both experimental and theoretical molecular spectroscopy contained in this book offers the reader insight into a wide range of techniques, particular emphasis being given to supersonic jet and matri...

  19. NATO Advanced Study Institute on Recent Advances in the Modeling of Hydrologic Systems

    CERN Document Server

    O’Connell, P

    1991-01-01

    Modeling of the rainfall-runoff process is of both scientific and practical significance. Many of the currently used mathematical models of hydrologic systems were developed a genera­ tion ago. Much of the effort since then has focused on refining these models rather than on developing new models based on improved scientific understanding. In the past few years, however, a renewed effort has been made to improve both our fundamental understanding of hydrologic processes and to exploit technological advances in computing and remote sensing. It is against this background that the NATO Advanced Study Institute on Recent Advances in the Modeling of Hydrologic Systems was organized. The idea for holding a NATO ASI on this topic grew out of an informal discussion between one of the co-directors and Professor Francisco Nunes-Correia at a previous NATO ASI held at Tucson, Arizona in 1985. The Special Program Panel on Global Transport Mechanisms in the Geo-Sciences of the NATO Scientific Affairs Division agreed to sp...

  20. NATO Advanced Study Institute on Buoyant Convection in Geophysical Flows

    CERN Document Server

    Fedorovich, E; Viegas, D; Wyngaard, J

    1998-01-01

    Studies of convection in geophysical flows constitute an advanced and rapidly developing area of research that is relevant to problems of the natural environment. During the last decade, significant progress has been achieved in the field as a result of both experimental studies and numerical modelling. This led to the principal revision of the widely held view on buoyancy-driven turbulent flows comprising an organised mean component with superimposed chaotic turbulence. An intermediate type of motion, represented by coherent structures, has been found to play a key role in geophysical boundary layers and in larger scale atmospheric and hydrospheric circulations driven by buoyant forcing. New aspects of the interaction between convective motions and rotation have recently been discovered and investigated. Extensive experimental data have also been collected on the role of convection in cloud dynamics and microphysics. New theoretical concepts and approaches have been outlined regarding scaling and parameteriz...

  1. Advanced Transportation Institute 2008.

    Science.gov (United States)

    2009-02-01

    The seventh version of the Advanced Transportation Institute (ATI-08) was conducted in 2008 to encourage high school students to pursue careers in the field of transportation engineering. The University Transportation Center for Alabama partnered wit...

  2. Advanced Transportation Institute 2009.

    Science.gov (United States)

    2009-09-01

    The eighth version of the Advanced Transportation Institute (ATI-09) was conducted in 2009 to encourage high school students to pursue careers in the field of transportation engineering. The University Transportation Center for Alabama partnered with...

  3. NATO Advanced Study Institute on Frontiers of Optical Spectroscopy

    CERN Document Server

    Bartolo, Baldassare

    2005-01-01

    Advanced spectroscopic techniques allow the probing of very small systems and very fast phenomena, conditions that can be considered "extreme" at the present status of our experimentation and knowledge. Quantum dots, nanocrystals and single molecules are examples of the former and events on the femtosecond scale examples of the latter. The purpose of this book is to examine the realm of phenomena of such extreme type and the techniques that permit their investigations. Each author has developed a coherent section of the program starting at a somewhat fundamental level and ultimately reaching the frontier of knowledge in the field in a systematic and didactic fashion. The formal lectures are complemented by additional seminars.

  4. Theoretical Advanced Study Institute in Elementary Particle Physics

    CERN Document Server

    2017-01-01

    The program will consist of a pedagogical series of lectures and seminars. Lectures will be given over a four-week period, three or four lectures per day, Monday through Friday. The audience will be composed primarily of advanced theoretical graduate students. Experimentalists with a strong background in theory are also encouraged to apply. Some post-doctoral fellows will be admitted, but preference will be given to applicants who will not have received their Ph.D. before 2017. The minimum background needed to get full benefit of TASI is a knowledge of quantum field theory (including RGEs) and familiarity with the Standard Model. Some familiarity with SUSY would be helpful. We hope to provide some subsidy, but students will need partial support from other sources. Rooms, meals, and access to all facilities will be provided at reasonable rates in beautifully located dormitories at the University of Colorado.

  5. NATO Advanced Study Institute on Magnetic Resonance : Introduction, Advanced Topics and Applications to Fossil Energy

    CERN Document Server

    Fraissard, Jacques

    1984-01-01

    This volume contains the lectures presented at an Advanced Study Institute on "Magnetic Resonance Techniques in Fossil Energy Problems," which was held at the village of Maleme, Crete, in July of 1983. As of this writing, a different popular attitude prevails from that when the ASI was proposed as far as how critical the world energy picture is. In the popular press, a panglossian attitude (the "petroleum glut" of the 80's) has replaced the jeremiads of the 70's ( a catastrophic "energy crisis"). Yet, there are certain important constants: (a) for the foreseeable future, fossil energy sources (petroleum, coal, oil shale, etc. ) will continue to be of paramount importance; and (b) science and technology of the highest order are needed to extend the fossil ener~y resource base and to utilize it in a cost-effective manner that is also environmentally acceptable. It is precisely this second item that this volume addresses. The volume introduces the phenomenology of magnetic resonance ~n a unified and detailed man...

  6. NATO Advanced Study Institute on High-Pressure Crystallography

    CERN Document Server

    Boldyreva, Elena; High-Pressure Crystallography

    2010-01-01

    This book is devoted to the theme of crystallographic studies at high pressure, with emphasis on the phenomena characteristic to the compressed state of matter, as well as experimental and theoretical techniques used to study these phenomena. As a thermodynamic parameter, pressure is remarkable in many ways. In the visible universe its value spans over sixty orders of magnitude, from the non-equilibrium pressure of hydrogen in intergalactic space, to the kind of pressure encountered within neutron stars. In the laboratory, it provides the unique possibility to control the structure and properties of materials, to dramatically alter electronic properties, and to break existing, or form new chemical bonds. This agenda naturally encompasses elements of physics (properties, structure and transformations), chemistry (reactions, transport), materials science (new materials) and engineering (mechanical properties); in addition it has direct applications and implications for geology (minerals in deep Earth environmen...

  7. NATO Advanced Study Institute on Sonochemistry and Sonoluminescence

    CERN Document Server

    Mason, Timothy; Reisse, Jacques; Suslick, Kenneth

    1999-01-01

    Sonochemistry is studied primarily by chemists and sonoluminescence mainly by physicists, but a single physical phenomenon - acoustic cavitation - unites the two areas. The physics of cavitation bubble collapse, is relatively well understood by acoustical physicists but remains practically unknown to the chemists. By contrast, the chemistry that gives rise to electromagnetic emissions and the acceleration of chemical reactions is familiar to chemists, but practically unknown to acoustical physicists. It is just this knowledge gap that the present volume addresses. The first section of the book addresses the fundamentals of cavitation, leading to a more extensive discussion of the fundamentals of cavitation bubble dynamics in section two. A section on single bubble sonoluminescence follows. The two following sections address the new scientific discipline of sonochemistry, and the volume concludes with a section giving detailed descriptions of the applications of sonochemistry. The mixture of tutorial lectures ...

  8. NATO Advanced Study Institute on Bio-Photonics

    CERN Document Server

    Bartolo, Baldassare Di

    2011-01-01

    This volume describes an impressive array of the current photonic-related technologies being used in the investigation of biological systems. The topics include various types of microscopy (fluorescence correlation microscopy, two-photon microscopy), sensitive detection of biological molecules, nano-surgery techniques, fluorescence resonance energy transfer, nano-plasmonics, terahertz spectroscopy, and photosynthetic energy conversion. The emphasis is on the physical principles behind each technique, and on examining the advantages and limitations of each.The book begins with an overview by Paras Prasad, a leader in the field of biophotonics, of several important optical techniques currently used for studying biological systems. In the subsequent chapters these techniques are discussed in depth, providing the reader with a detailed understanding of the basic physical principles at work. An excellent treatment of terahertz spectroscopy demonstrates how photonics is being extended beyond the visible region. Rec...

  9. NATO Advanced Study Institute on Molecular Physics and Hypersonic Flows

    CERN Document Server

    1996-01-01

    Molecular Physics and Hypersonic Flows bridges the gap between the fluid dynamics and molecular physics communities, emphasizing the role played by elementary processes in hypersonic flows. In particular, the work is primarily dedicated to filling the gap between microscopic and macroscopic treatments of the source terms to be inserted in the fluid dynamics codes. The first part of the book describes the molecular dynamics of elementary processes both in the gas phase and in the interaction with surfaces by using quantum mechanical and phenomenological approaches. A second group of contributions describes thermodynamics and transport properties of air components, with special attention to the transport of internal energy. A series of papers is devoted to the experimental and theoretical study of the flow of partially ionized gases. Subsequent contributions treat modern computational techniques for 3-D hypersonic flow. Non-equilibrium vibrational kinetics are then described, together with the coupling of vibra...

  10. NATO Advanced Study Institute on Optics in Astrophysics

    CERN Document Server

    Foy, Renaud

    2005-01-01

    Astrophysics is facing challenging aims such as deep cosmology at redshift higher than 10 to constrain cosmology models, or the detection of exoplanets, and possibly terrestrial exoplanets, and several others. It requires unprecedented ambitious R&D programs, which have definitely to rely on a tight cooperation between astrophysics and optics communities. The book addresses most of the most critical interdisciplinary domains where they interact, or where they will do. A first need is to collect more light, i.e. telescopes still larger than the current 8-10 meter class ones. Decametric, and even hectometric, optical (from UV to IR wavelengths) telescopes are being studied. Whereas up to now the light collecting surface of new telescopes was approximately 4 times that of the previous generation, now this factor is growing to 10 to 100. This quantum leap urges to implement new methods or technologies developed in the optics community, both in academic labs and in the industry. Given the astrophysical goals a...

  11. NATO Advanced Study Institute on Preparation and Properties of Stereoregular Polymers

    CERN Document Server

    Ciardelli, Francesco

    1980-01-01

    This book contains the texts of the main lectures presented at the NATO Advanced Studies Institute on "Advances in Preparation and Properties of Stereoregular Polymers" held at Tirrenia near Pisa, Italy, from October 3 to 14, 1978. A few contributed papers have also been included because they were concerned with topics not included in the main lectures. The primary objective of the Institute was to assist in the further development of stereoregular polymers because of the ever-increasing demand for new products with exceptional chemical and physical properties. This need has reawakened interest in the field. Indeed there is now a rapidly increasing activity in the study of stereoregular polymerization and the preparation of structurally-ordered polymers with the aim of achieving apprecia­ ble improvements in existing polymeric materials through new developments in synthesis and properties as well as in discovering new polymeric structures. In order to achieve these objectives, a broad interdiscipli­ nary co...

  12. NATO Advanced Study Institute and International School of Materials Science and Technology

    CERN Document Server

    Balkanski, Minko; 15th Course on Solid State Microbatteries

    1990-01-01

    This Advanced Study Institute on the topic of SOLID STATE MICROBATTERIES is the third and final institute on the general theme of a field of study now termed "SOLID STATE IONICS". The institute was held in Erice, Sicily, Italy, 3 - 15 July 1988. The objective was to assemble in one location individuals from industry and academia expert in the fields of microelectronics and solid state ionics to determine the feasibility of merging a solid state microbattery with microelectronic memory. Solid electrolytes are in principle amenable to vapor deposition, RF or DC sputtering, and other techniques used to fabricate microelectronic components. A solid state microbattery 1 1 mated on the same chip carrier as the chip can provide on board memory backup power. A solid state microbattery assembled from properly selected anode/solid electrolyte/cathode materials could have environmental endurance properties equal or superior to semiconductor memory chips. Lectures covering microelectronics, present state-of-art solid sta...

  13. Antwerp Advanced Study Institute on Electronic Structure, Dynamics and Quantum Structural Properties of Condensed Matter

    CERN Document Server

    Camp, Piet

    1985-01-01

    The 1984 Advanced Study Institute on "Electronic Structure, Dynamics and Quantum Structural Properties of Condensed Matter" took place at the Corsendonk Conference Center, close to the City of Antwerpen, from July 16 till 27, 1984. This NATO Advanced Study Institute was motivated by the research in my Institute, where, in 1971, a project was started on "ab-initio" phonon calculations in Silicon. I~ is my pleasure to thank several instances and people who made this ASI possible. First of all, the sponsor of the Institute, the NATO Scientific Committee. Next, the co-sponsors: Agfa-Gevaert, Bell Telephone Mfg. Co. N.V., C & A, Esso Belgium·, CDC Belgium, Janssens Pharmaceutica, Kredietbank and the Scientific Office of the U.S. Army. Special thanks are due to Dr. P. Van Camp and Drs. H. Nachtegaele, who, over several months, prepared the practical aspects of the ASI with the secretarial help of Mrs. R.-M. Vandekerkhof. I also like to. thank Mrs. M. Cuyvers who prepared and organized the subject and material ...

  14. NATO Advanced Study Institute on Advanced Nanotechnologies for Detection and Defence

    CERN Document Server

    Tsiulyanu, Dumitru; Popov, Cyril; Kulisch, Wilhelm; Advanced nanotechnologies for detection and defence against CBRN agents

    2018-01-01

    This volume gives a broad overview of advanced technologies for detection and defence against chemical, biological, radiological and nuclear (CBRN) agents. It provides chapters addressing the preparation and characterization of different nanoscale materials (metals, oxides, glasses, polymers, carbon-based, etc.) and their applications in fields related to security and safety. In addition, it presents an interdisciplinary approach as the contributors come from different areas of research, such as physics, chemistry, engineering, materials science and biology. A major feature of the book is the combination of longer chapters introducing the basic knowledge on a certain topic, and shorter contributions highlighting specific applications in different security areas.

  15. NATO Advanced Study Institute International Advanced Course on The Liquid State and Its Electrical Properties

    CERN Document Server

    Christophorou, L; Luessen, L

    1988-01-01

    As the various disciplines of science advance, they proliferate and tend to become more esoteric. Barriers of specialized terminologies form, which cause scientists to lose contact with their colleagues, and differences in points-of-view emerge which hinder the unification of knowledge among the various disciplines, and even within a given discipline. As a result, the scientist, and especially the student, is in many instances offered fragmented glimpses of subjects that are funda­ mentally synthetic and that should be treated in their own right. Such seems to be the case of the liquid state. Unlike the other states of matter -- gases, solids, and plasmas -- the liquid state has not yet received unified treatment, probably because it has been the least explored and remains the least understood state of matter. Occasionally, events occur which help remove some of the barriers that separate scientists and disciplines alike. Such an event was the ASI on The Liquid State held this past July at the lovely Hotel T...

  16. NATO Advanced Study Institute on Nondestructive Evaluation of Semiconductor Materials and Devices

    CERN Document Server

    1979-01-01

    From September 19-29, a NATO Advanced Study Institute on Non­ destructive Evaluation of Semiconductor Materials and Devices was held at the Villa Tuscolano in Frascati, Italy. A total of 80 attendees and lecturers participated in the program which covered many of the important topics in this field. The subject matter was divided to emphasize the following different types of problems: electrical measurements; acoustic measurements; scanning techniques; optical methods; backscatter methods; x-ray observations; accele­ rated life tests. It would be difficult to give a full discussion of such an Institute without going through the major points of each speaker. Clearly this is the proper task of the eventual readers of these Proceedings. Instead, it would be preferable to stress some general issues. What came through very clearly is that the measurements of the basic scientists in materials and device phenomena are of sub­ stantial immediate concern to the device technologies and end users.

  17. NATO Advanced Study Institute on Electronic Structure of Polymers and Molecular Crystals

    CERN Document Server

    Ladik, János

    1975-01-01

    The NATO Advanced Study Institute on "Electronic Structure of Polymers and Molecular Crystals" was held at the Facultes Universi­ taires de Namur (F.U.N.) from September 1st till September 14th, 1974. We wish to express our appreciation to the NATO Scientific Affairs Division whose generous support made this Institute possible and to the Facultes Universitaires de Namur and the Societe Chimique de Belgique which provided fellowships and travel grants to a number of students. This volume contains the main lectures about the basic principles of the field and about different recent developments of the theory of the electronic structure of polymers and molecular crystals. The school started with the presentation of the basic SCF-LCAO theory of the electronic structure of periodic polymers and molecular crystals (contributions by Ladik, Andre & Delhalle) showing how a combination of quantum chemical and solid state physical methods can provide band structures for these systems. The numerical aspects of these ...

  18. NATO Advanced Study Institute on Nano-Optics : Principles Enabling Basic Research and Applications

    CERN Document Server

    Collins, John; Silvestri, Luciano

    2017-01-01

    This book provides a comprehensive overview of nano-optics, including basic theory, experiment and applications, particularly in nanofabrication and optical characterization. The contributions clearly demonstrate how advances in nano-optics and photonics have stimulated progress in nanoscience and -fabrication, and vice versa. Their expert authors address topics such as three-dimensional optical lithography and microscopy beyond the Abbe diffraction limit, optical diagnostics and sensing, optical data- and telecommunications, energy-efficient lighting, and efficient solar energy conversion. Nano-optics emerges as a key enabling technology of the 21st century. This work will appeal to a wide readership, from physics through chemistry, to biology and engineering. The contributions that appear in this volume were presented at a NATO Advanced Study Institute held in Erice, 4-19 July, 2015.

  19. NATO Advanced Study Institute on Laser Control & Monitoring in New Materials, Biomedicine, Environment, Security & Defense

    CERN Document Server

    Hall, Trevor J; Paredes, Sofia A; Extreme Photonics & Applications

    2010-01-01

    "Extreme Photonics & Applications" arises from the 2008 NATO Advanced Study Institute in Laser Control & Monitoring in New Materials, Biomedicine, Environment, Security and Defense. Leading experts in the manipulation of light offered by recent advances in laser physics and nanoscience were invited to give lectures in their fields of expertise and participate in discussions on current research, applications and new directions. The sum of their contributions to this book is a primer for the state of scientific knowledge and the issues within the subject of photonics taken to the extreme frontiers: molding light at the ultra-finest scales, which represents the beginning of the end to limitations in optical science for the benefit of 21st Century technological societies. Laser light is an exquisite tool for physical and chemical research. Physicists have recently developed pulsed lasers with such short durations that one laser shot takes the time of one molecular vibration or one electron rotation in an ...

  20. The NATO Advanced Study Institute on New Vistas in Electro-Nuclear Physics

    CERN Document Server

    Caplan, H S; Dressler, E T; The NATO Advanced Study Institute on New Vistas in Electro-Nuclear Physics

    1986-01-01

    The NATO Advanced Study Institute "New Vistas in Electro-Nuclear Physics" was held in Banff, Alberta, Canada from August 22 to September 4, 1985. This volume con­ tains the lecture notes from that Institute. The idea to organize this Institute coincided with the award of funding for a pulse stretcher ring at the University of Saskatchewan's Linear Accelerator Laboratory. This together with the high level of interest in electron accelerators worldwide convinced us that it was an appropriate time to discuss the physics to be learned with such machines. In particular that physics which requires high energy and/or high duty cycle accelerators for its extraction was intended to be the focus of the Institute. Thus the scope of the lec­ tures was wide, with topics ranging from the structure of the trinucleons to quark models of nucleons, QCD, and QHD. The theme however was that we are just trying to under­ stand the nucleus and that the electromagnetic probe can serve as a powerful tool in such a quest.

  1. NATO Advanced Study Institute on Relativistic and Electron Correlation Effects in Molecules and Solids

    CERN Document Server

    1994-01-01

    The NATO Advanced Study Institute (ASI) on "R@lativistic and Electron Correlation Effects in Molecules and Solids", co-sponsored by Simon Fraser University (SFU) and the Natural Sciences and Engineering Research Council of Canada (NSERC) was held Aug 10- 21, 1992 at the University of British Columbia (UBC), Vancouver, Canada. A total of 90 lecturers and students with backgrounds in Chemistry, Physics, Mathematics and various interdisciplinary subjects attended the ASI. In my proposal submitted to NATO for financial support for this ASI, I pointed out that a NATO ASI on the effects of relativity in many-electron systems was held ten years ago, [See G.L. Malli, (ed) Relativistic Effects in Atoms, Molecules and Solids, Plenum Press, Vol B87, New York, 1983]. Moreover, at a NATO Advanced Research Workshop (ARW) on advanced methods for molecular electronic structure "an assessment of state-of­ the-art of Electron Correlation ... " was carried out [see C.E. Dykstra, (ed), Advanced Theories and Computational Approa...

  2. NATO Advanced Study Institute on Microscopic Simulations of Complex Hydrodynamic Phenomena

    CERN Document Server

    Holian, Brad

    1992-01-01

    This volume contains the proceedings of a NATO Advanced Study Institute which was held in Alghero, Sardinia, in July 1991. The development of computers in the recent years has lead to the emergence of unconventional ideas aiming at solving old problems. Among these, the possibility of computing directly fluid flows from the trajectories of constituent particles has been much exploited in the last few years: lattice gases cellular automata and more generally Molecular Dynamics have been used to reproduce and study complex flows. Whether or not these methods may someday compete with more traditional approaches is a question which cannot be answered at the present time: it will depend on the new computer architectures as well as on the possibility to develop very simple models to reproduce the most complex phenomena taking place in the approach of fully developed turbulence or plastic flows. In any event, these molecular methods are already used, and sometimes in an applied engineering context, to study strong s...

  3. NATO Advanced Study Institute on Synthetic Membranes : Science, Engineering and Applications

    CERN Document Server

    Lonsdale, H; Pinho, M

    1986-01-01

    The chapters in this book are based upon lectures given at the NATO Advanced Study Institute on Synthetic Membranes (June 26-July 8, 1983, Alcabideche, Portugal), which provided an integrated presentation of syn­ thetic membrane science and technology in three broad areas. Currently available membrane formation mechanisms are reviewed, as well as the manner in which synthesis conditions can be controlled to achieve desired membrane structures. Membrane performance in a specific separa­ tionprocess involves complex phenomena, the understanding of which re­ quires a multidisciplinary approach encompassing polymer chemistry, phys­ ical chemistry, and chemical engineering. Progress toward a global understanding of membrane phenomena is described in chapters on the principles of membrane transport. The chapters on membrane processes and applications highlight both established and emerging membrane processes, and elucidate their myriad applications. It is our hope that this book will be an enduring, comprehensi...

  4. NATO Advanced Study Institute on Pollutants from Combustion Formation and Impact on Atmospheric Chemistry

    CERN Document Server

    2000-01-01

    This volume is based on the lectures presented at the NATO Advanced Study Institute: (ASI) «Pollutants Formation from Combustion. Formation Mechanisms and Impact on th th Atmospheric Chemistry» held in Maratea, Italy, from 13 to 26 september 1998. Preservation of the environment is of increasing concern in individual countries but also at continental or world scales. The structure of a NATO ASI which involve lecturers and participants of different nationalities was thought as especially well suited to address environmental issues. As combustion is known to substantially contribute to the damaging of the atmosphere, it was natural to concentrate the ASI program on reviewing the currently available knowledge of the formation mechanisms of the main pollutants liberated by combustion systems. In most situations, pollutants are present as trace components and their formation and removal is strongly conditioned by the chemical reactions initiated by fuel consumption. Therefore specific lectures were aimed at defi...

  5. NATO Advanced Study Institute on Statistical Treatments for Estimation of Mineral and Energy Resources

    CERN Document Server

    Fabbri, A; Sinding-Larsen, R

    1988-01-01

    This volume contains the edited papers prepared by lecturers and participants of the NATO Advanced Study Institute on "Statistical Treatments for Estimation of Mineral and Energy Resources" held at II Ciocco (Lucca), Italy, June 22 - July 4, 1986. During the past twenty years, tremendous efforts have been made to acquire quantitative geoscience information from ore deposits, geochemical, geophys ical and remotely-sensed measurements. In October 1981, a two-day symposium on "Quantitative Resource Evaluation" and a three-day workshop on "Interactive Systems for Multivariate Analysis and Image Processing for Resource Evaluation" were held in Ottawa, jointly sponsored by the Geological Survey of Canada, the International Association for Mathematical Geology, and the International Geological Correlation Programme. Thirty scientists from different countries in Europe and North America were invited to form a forum for the discussion of quantitative methods for mineral and energy resource assessment. Since then, not ...

  6. NATO Advanced Study Institute on Photophysical and Photochemical Tools in Polymer Science : Conformation, Dynamics, Morphology

    CERN Document Server

    1986-01-01

    In 1980 the New York Academy of Sciences sponsored a three-day conference on luminescence in biological and synthetic macromolecules. After that meeting, Professor Frans DeSchryver and I began to discuss the possibility of organizing a different kind of meeting, with time for both informal and in-depth discussions, to examine certain aspects of the application of fluorescence and phosphorescence spectroscopy to polymers. Our ideas developed through discussions with many others, particularly Professor Lucien Monnerie. By 1983, when we submitted our proposal to NATO for an Advanced Study Institute, the area had grown enormous ly. It is interesting in retrospect to look back on the points which emerged from these discussions as the basis around which the scientific program would be organized and the speakers chosen. We decided early on to focus on applications of these methods to provide information about polymer molecules and polymer systems: The topics would all relate to the conformation and dynamics of macro...

  7. NATO Advanced Study Institute on Lower-Dimensional Systems and Molecular Electronics

    CERN Document Server

    Day, Peter; Papavassiliou, George

    1990-01-01

    This volume represents the written account of the NATO Advanced Study Institute "Lower-Dimensional Systems and Molecular Electronics" held at Hotel Spetses, Spetses Island, Greece from 12 June to 23 June 1989. The goal of the Institute was to demonstrate the breadth of chemical and physical knowledge that has been acquired in the last 20 years in inorganic and organic crystals, polymers, and thin films, which exhibit phenomena of reduced dimensionality. The interest in these systems started in the late 1960's with lower-dimensional inorganic conductors, in the early 1970's with quasi-one-dimensional crystalline organic conductors. which by 1979 led to the first organic superconductors, and, in 1977, to the fITSt conducting polymers. The study of monolayer films (Langmuir-Blodgett films) had progressed since the 1930's, but reached a great upsurge in . the early 1980's. The pursuit of non-linear optical phenomena became increasingly popular in the early 1980's, as the attention turned from inorganic crystals t...

  8. NATO Advanced Study Institute on Ring-opening Metathesis Polymerization of Olefins and Polymerization of Alkynes

    CERN Document Server

    1998-01-01

    The first NATO Advanced Study Institute on Olefin Metathesis and Polymerization Catalysts was held on September 10-22, 1989 in Akcay, Turkey. Based on the fundamental research of RRSchrock, RGrubbs and K.B.Wagener in the field of ring opening metathesis polymerization (ROMP), acyclic diene metathesis (ADMET) and alkyne polymerization, these areas gained growing interest within the last years. Therefore the second NATO-ASI held on metathesis reactions was on Ring Opening Metathesis Po­ lymerization of Olefins and Polymerization of Alkynes on September 3-16, 1995 in Akcay, Turkey. The course joined inorganic, organic and polymer chemists to exchange their knowledge in this field. This volume contains the main and short lectures held in Akcay. To include ADMET reactions better into the title of this volume we changed it into: Metathesis Polymerization of Olefins and Alkyne Polymerization. This volume is addressed to research scientists, but also to those who start to work in the area of olefin metathesis and al...

  9. NATO Advanced Study Institute on Instabilities and Chaos in Quantum Optics

    CERN Document Server

    Arecchi, F; Lugiato, L; Instabilities and Chaos in Quantum Optics II

    1988-01-01

    This volume contains tutorial papers from the lectures and seminars presented at the NATO Advanced Study Institute on "Instabilities and Chaos in Quantum Optics", held at the "Il Ciocco" Conference Center, Castelvecchio Pascoli, Lucca, Italy, June 28-July 7, 1987. The title of the volume is designated Instabilities and Chaos in Quantum Optics II, because of the nearly coincident publication of a collection of articles on research in this field edited by F.T. Arecchi and R.G. Harrison [Instabilities and Chaos in Quantum Optics, (Springer, Berlin, 1987) 1. That volume provides more detailed information about some of these topics. Together they will serve as a comprehensive and tutorial pair of companion volumes. This school was directed by Prof. Massimo Inguscio, of the Department of Physics, University of Naples, Naples, Italy to whom we express our gratitude on behalf of all lecturers and students. The Scientific Advisory Committee consisted of N.B. Abraham of Bryn Mawr College; F.T. Arecchi of the National I...

  10. NATO Advanced Study Institute on Laser Interactions with Atoms, Solids,and Plasmas

    CERN Document Server

    1994-01-01

    The aim of this NATO Advanced Study Institute was to bring together scientists and students working in the field of laser matter interactions in order to review and stimulate developmentoffundamental science with ultra-short pulse lasers. New techniques of pulse compression and colliding-pulse mode-locking have made possible the construction of lasers with pulse lengths in the femtosecond range. Such lasers are now in operation at several research laboratories in Europe and the United States. These laser facilities present a new and exciting research direction with both pure and applied science components. In this ASI the emphasis is on fundamental processes occurring in the interaction of short laser pulses with atoms, molecules, solids, and plasmas. In the case of laser-atom (molecule) interactions, high power lasers provide the first access to extreme high-intensity conditions above 10'8 Watts/em', a new frontier for nonlinear interaction of photons with atoms and molecules. New phenomena observed include ...

  11. Smithsonian Institution. Opportunities for Research and Advanced Study 1970-1971.

    Science.gov (United States)

    Smithsonian Institution, Washington, DC. Office of Academic Programs.

    This book describes study and research programs and facilities at the Smithsonian Institution in 9 academic areas: 1) History of Science and Technology; 2) American Studies; 3) Cultural Studies; 4) Museum Studies; 5) Anthropology; 6) Evolutionary and Systematic Biology; 7) Environmental Biology; 8) Evolutionary and Behavioral Biology, Tropical…

  12. Human-machine communication for educational systems design : NATO Advanced Study Institute proceedings, Eindhoven August 16-26, 1993

    NARCIS (Netherlands)

    Janse, M.D.; Harrington, T.L.

    1994-01-01

    This book contains the papers presented at the NATO Advanced Study Institute (ASI) on the Basics of Man-Machine Communication for the Design of Educational Systems, held August 16-26, 1993 in Eindhoven, The Netherlands. The ASI addressed the state of the art in the design of educational systems with

  13. Strategic Institutional Change to Support Advancement of Women Scientists in the Academy: Lessons from a Study of ADVANCE-IT Projects

    Science.gov (United States)

    Laursen, S. L.; Austin, A. E.; Soto, M.; Martinez, D.

    2011-12-01

    While women's representation among undergraduate and graduate degree-earners has grown steadily in most science fields, progress at the faculty level has been slow to realize, especially in upper academic ranks and in higher status institutions. This is only partly explained by the slow turnover of faculty positions. While some efforts to address this issue have aimed to support individual women and foster their career success, the National Science Foundation's ADVANCE program has taken a different approach, calling for institutions to take a systemic and organizational approach to enhance women's representation in the academy. Since 2001, some 50 institutions have received ADVANCE Institutional Transformation (IT) awards to develop such systemic approaches. Most ADVANCE-IT projects have attended to structures (e.g. committee and departmental leadership roles), processes (e.g. hiring), policy (e.g. family leave), attitudes and awareness (e.g. training for chairs), and workplace climate, as well as interventions that focus on faculty members as valuable human resources. Our research team is studying ADVANCE institutions' approaches to organizational change, by identifying and categorizing individual change interventions, examining how they combine to build an overall change portfolio, and considering how change interventions are selected or adapted to fit a specific institutional context. Because universities are complex organizations composed of multiple, loosely coupled, interconnected sub-systems, an overall change strategy cannot depend on a single type of intervention. Yet any particular intervention might be deployed on behalf of multiple goals and in a variety of forms that may depend on the context, or institutional system, in which it is introduced. We will discuss some common types of strategic intervention used in ADVANCE-IT projects, categorized by Bolman and Deal's (1991) four main perspectives or "lenses" for understanding organizational issues. The

  14. NATO Advanced Study Institute on Magnetic Nanostructures for Micro-Electromechanical Systems and Spintronic Applications

    CERN Document Server

    Azzerboni, Bruno; Pareti, Luigi; Ghidini, Massimo

    2007-01-01

    Proposes a synergic junction between the characteristic expertise of the engineering and the knowledge of the basic scienceThe main effect should be a cross-cultural fertilization favoring an interdisciplinary enrichment for the readers and their research perspectivesCovers the most advanced fields of modern magnetic nano-technologiesA unique source of up to date information for the young physicist, chemist or engineer as well as a crucial reference for the expert scientist and the teacher of advanced university coursesDeals with the most important topics in the field of modern magnetism in fu

  15. NATO Advanced Study Institute on Optical Waveguide Sensing and Imaging in Medicine, Environment, Security and Defence

    CERN Document Server

    Bock, Wojtek J; Tanev, Stoyan

    2008-01-01

    The book explores various aspects of existing and emerging fiber and waveguide optics sensing and imaging technologies including recent advances in nanobiophotonics. The focus is both on fundamental and applied research as well as on applications in civil engineering, biomedical sciences, environment, security and defence. The main goal of the multi-disciplinarry team of Editors was to provide an useful reference of state-of-the-art overviews covering a variety of complementary topics on the interface of engineering and biomedical sciences.

  16. Phase II study of chemoradiotherapy for advanced squamous cell carcinoma of the thoracic esophagus. Nine Japanese institutions trial

    Energy Technology Data Exchange (ETDEWEB)

    Ishida, Kaoru [Iwate Medical Univ., Morioka (Japan). School of Medicine; Iizuka, Toshifumi; Ando, Nobutoshi; Ide, Hiroko

    1996-10-01

    A phase II study of chemoradiotherapy for advanced squamous cell carcinoma of the thoracic esophagus was carried out cooperatively by nine Japanese institutions. Forty-five patients with thoracic advanced squamous cell carcinoma, who had T4 tumor or distant lymph node metastasis (M1{sub (LYM)}), were enrolled in the study for treatment with cisplatin (70 mg/m{sup 2}) on days 1 and 36, and 5-fluorouracil infusion (700 mg/m{sup 2}) on days 1-4 and 36-39 sandwiched around external beam irradiation (60 Gy over 6 weeks). Of the 45 evaluable patients, 37 (84.1%) completed the treatment. The overall response rate was 64.4%, and the complete response rate 8.9%. The median duration of response was 125.0 days for patients who achieved complete and partial response. The 50% median survival time was 215 days. There was one toxicity-related death due to radiation pneumonitis. The major form of toxicity exceeding grade 2 was myelosuppression and anorexia, but grade 4 toxicity was also observed (2 pulmonary, 1 severe hypoxemia, 1 severe cardiac failure and 1 mental disturbance). The results showed that this form of chemoradiotherapy had a satisfactory effect and might be useful for treatment of inoperable advanced esophageal cancer. (author)

  17. NATO Advanced Study Institute on Topics in Atomic and Nuclear Collisions

    CERN Document Server

    Rémaud, B; Zoran, V

    1994-01-01

    The ASI 'Topics in Atomic and Nuclear Collisions' was organized in Predeal from August 31 to September 11. It brought together people with a broad interest in Atomic and Nuclear Physics from several research institutes and universities in Ro­ mania and 16 other countries. The school continues a tradition that started on a small scale back in 1968, fo­ cussing mainly on current problems in nuclear physics. Though the organizing of this edition started very late and in very uncertain economic and financial conditions, it turned out to be the largest meeting of this type ever organized in Romania, both in topics and participation. There were many applicants for participation and grants, considerably more than could be handled. The selection made by the local organizing committee was based on the following criteria: a proper balance of atomic and nuclear physicists, a broad representation of people from Research Institutes and Universities, a balanced par­ ticipat!on with respect to age, sex, nationali...

  18. NATO Advanced Study Institute on Improved Methods for Examining the Submicron World

    CERN Document Server

    McGowan, J; Shinozaki, Douglas

    1986-01-01

    An Institute like ours cannot help but lend credence to the notion of the late Derek J. de Solla Price of Yale University that "the scientific revolution was largely the improvement, invention and use of a series of instruments . . . . that expanded the reach of science in innumerable directions". Most of science today and in years gone by depends on the experimental observation of struc­ ture on the small scale with microscopes, and on the large scale with telescopes. The first instruments to expand the observational range of the human eye were simple optical systems, designed in the case of microscopes and telescopes to magnify the image. The big breakthrough in the 17th century was not when Galileo first turned his telescope to the heavens, but when improvements in lens-grinding techniques allowed eyeglass makers to make the first telescope. Early microscopy revealed new and previously unsuspected microstruc­ tures in biological and non-biological materials and thus helped to enlarge on the understanding...

  19. Multidisciplinary Service Utilization Pattern by Advanced Head and Neck Cancer Patients: A Single Institution Study

    Directory of Open Access Journals (Sweden)

    Jacqueline C. Junn

    2012-01-01

    Full Text Available Purpose. To analyze the patterns and associations of adjunctive service visits by head and neck cancer patients receiving primary, concurrent chemoradiation therapy. Methods. Retrospective chart review of patients receiving adjunctive support during a uniform chemoradiation regimen for stages III-IV head and neck squamous cell carcinoma. Univariate and multivariate models for each outcome were obtained from simple and multivariate linear regression analyses. Results. Fifty-two consecutive patients were assessed. Female gender, single marital status, and nonprivate insurance were factors associated with an increased number of social work visits. In a multivariate analysis, female gender and marital status were related to increased social work services. Female gender and stage IV disease were significant for increased nursing visits. In a multivariate analysis for nursing visits, living greater than 20 miles between home and hospital was a negative predictive factor. Conclusion. Treatment of advanced stage head and neck cancer with concurrent chemoradiation warrants a multidisciplinary approach. Female gender, single marital status, and stage IV disease were correlated with increased utilization of social work and nursing services. Distance over 20 miles from the center was a negative factor. This information may help guide the treatment team to allocate resources for the comprehensive care of patients.

  20. NATO Advanced Study Institute on Chemical Crystallography with Pulsed Neutrons and Synchrotron X-Rays

    CERN Document Server

    Jeffrey, George

    1988-01-01

    X-ray and neutron crystallography have played an increasingly impor­ tant role in the chemical and biochemical sciences over the past fifty years. The principal obstacles in this methodology, the phase problem and com­ puting, have been overcome. The former by the methods developed in the 1960's and just recognised by the 1985 Chemistry Nobel Prize award to Karle and Hauptman, the latter by the dramatic advances that have taken place in computer technology in the past twenty years. Within the last decade, two new radiation sources have been added to the crystallographer's tools. One is synchrotron X-rays and the other is spallation neutrons. Both have much more powerful fluxes than the pre­ vious sources and they are pulsed rather than continuos. New techniques are necessary to fully exploit the intense continuos radiation spectrum and its pulsed property. Both radiations are only available from particular National Laboratories on a guest-user basis for scientists outside these Na­ tional Laboratories. Hi...

  1. NATO Advanced Study Institute on Nano-Optics for Enhancing Light-Matter Interactions on a Molecular Scale

    CERN Document Server

    Collins, John

    2013-01-01

    This volume presents a considerable number of interrelated contributions dealing with the new scientific ability to shape and control matter and electromagnetic fields on a sub-wavelength scale. The topics range from the fundamental ones, such as photonic metamateriials, plasmonics and sub-wavelength resolution to the more applicative, such as detection of single molecules, tomography on a micro-chip, fluorescence spectroscopy of biological systems, coherent control of biomolecules, biosensing of single proteins, terahertz spectroscopy of nanoparticles, rare earth ion-doped nanoparticles, random lasing, and nanocoax array architecture. The various subjects bridge over the disciplines of physics, biology and chemistry, making this volume of interest to people working in these fields. The emphasis is on the principles behind each technique and on examining the full potential of each technique. The contributions that appear in this volume were presented at a NATO Advanced Study Institute that was held in Erice, ...

  2. NATO Advanced Study Institute on Electron and Magnetization Densities in Molecules and Crystals

    CERN Document Server

    1980-01-01

    The interest of describing the ground state properties of a system in terms of one electron density (or its two spin components) is obvious, in particular due to the simple physical significance of this function. Recent experimental progress in diffraction made the measurement of charge and magnetization densities in crystalline solids possible, with an accuracy at least as good as theoretical accuracy. Theoretical developments of the many-body problem have proved the extreme importance of the one electron density function and presently, accurate methods of band structure determination become available. Parallel to the diffraction techniques, other domains of research (inelastic scattering, resonance, molecular spectroscopy) deal with quantities directly related to the one particle density. But the two types of studies do not interfere enough and one should obviously gain more information by interpreting all experiments that are related to the density together. It became necessary to have an International Sch...

  3. NATO Advanced Study Institute on Giant Resonances in Atoms, Molecules, and Solids

    CERN Document Server

    Esteva, J; Karnatak, R

    1987-01-01

    Often, a new area of science grows at the confines between recognised subject divisions, drawing upon techniques and intellectual perspectives from a diversity of fields. Such growth can remain unnoticed at first, until a characteristic fami ly of effects, described by appropriate key words, has developed, at which point a distinct subject is born. Such is very much the case with atomic 'giant resonances'. For a start, their name itself was borrowed from the field of nuclear collective resonances. The energy range in which they occur, at the juncture of the extreme UV and the soft X-rays, remains to this day a meeting point of two different experimental techniques: the grating and the crystal spectrometer. The impetus of synchrotron spectroscopy also played a large part in developing novel methods, described by many acronyms, which are used to study 'giant resonances' today. Finally, although we have described them as 'atomic' to differentiate them from their counterparts in Nuclear Physics, their occurrence ...

  4. NATO Advanced Study Institute on Structural Theory of Automata, Semigroups and Universal Algebra

    CERN Document Server

    Rosenberg, Ivo; Goldstein, Martin

    2005-01-01

    Several of the contributions to this volume bring forward many mutually beneficial interactions and connections between the three domains of the title. Developing them was the main purpose of the NATO ASI summerschool held in Montreal in 2003. Although some connections, for example between semigroups and automata, were known for a long time, developing them and surveying them in one volume is novel and hopefully stimulating for the future. Another aspect is the emphasis on the structural theory of automata that studies ways to contstruct big automata from small ones. The volume also has contributions on top current research or surveys in the three domains. One contribution even links clones of universal algebra with the computational complexity of computer science. Three contributions introduce the reader to research in the former East block.

  5. NATO Advanced Study Institute on Fundamental and Technological Aspects of Organo-f-Element Chemistry

    CERN Document Server

    Fragalà, Ignazio

    1985-01-01

    The past decade has seen a dramatic acceleration of activity and interest in phenomena surrounding lanthanide and actinide organo­ metallic compounds. Around the world, active research in organo-f­ element synthesis, chemistry, catalysis, crystallography, and quantum chemistry is in progress. This activity has spanned a remarkably wide range of disciplines, from synthetic/mechanistic inorganic and organic chemistry to radiochemistry, catalytic chemistry, spectroscopy (vibra­ tional, optical, magnetic resonance, photoelectron, Mossbauer), X-ray and neutron diffraction structural analysis, as well as to crystal field and molecular orbital theoretical studies at the interface of chemistry and physics. These investigations have been motivated both by fundamental and applied goals. The evidence that f-element organo­ metallic compounds have unique chemical and physical properties which cannot be duplicated by organometallic compounds of d-block elements has suggested many new areas of endeavor and application....

  6. NATO Advanced Study Institute on Systematics and the Properties of the Lanthanides

    CERN Document Server

    1983-01-01

    Science is not a mere collection of facts. It is the correlation of facts, the interpretative synthesis of the available knowledge and its application that excite the imagination of a scientist. Even in these days of modern technology, the need for quick and accurate dissemination of new information and current concepts still exists. Conferences and Symposia offer one direct method of communication. The Summer Schools are another approach. The success of a Summer School is mainly due to that human factor and under­ standing that goes with it and allows for extensive and often time-unrestricted discussions. During the course of the past 20 years, one of the most in­ tensively studied groups of elements in the Periodic Table is the Lanthanides. In this period, we have increased our knowledge on these once exotic elements, which were once considered to be a part of a lean and hungry industry, many-fold due to the involve­ ment of scientists from various disciplines. The purpose of our Summer School was to bri...

  7. Annual report 90. Institute for advanced materials

    International Nuclear Information System (INIS)

    1991-01-01

    The Annual Report 1990 of the Institute for Advanced Materials of the JRC highlights the Scientific Technical Achievements and presents in the Annex the Institute's Competence and Facilities available to industry for services and research under contract. The Institute executed in 1990 the R and D programme on advanced materials of the JRC and contributed to the programmes: reactor safety, radio-active waste management, fusion technology and safety, nuclear fuel and actinide research. The supplementary programme: Operation of the High Flux Reactor is presented in condensed form. A full report is published separately

  8. Chemo-radiotherapy plus hyperthermia in locally advanced cervical cancer: preliminary results of an institutional phase II study

    International Nuclear Information System (INIS)

    Gabbani, M.; Marciai, N.; Maluta, S.; Griso, C.; Merlin, F.; Cassandrini, P.; Giudici, S.; Franchi, M.; Zanini, L.

    2005-01-01

    Full text: Radiotherapy given concurrently with a cisplatin-based regimen has shown a benefit in patients with locally advanced cervical cancer so becoming the new standard treatment according to EBM criteria. Addition of hyperthermia to radiotherapy has also been proved to yield an advantage in survival and local control in pts affected by recurrent and local advanced cervical cancer in the Dutch Phase III trial so that the Consensus Forum of Kadota (Osaha June 2004) included cervical cancer among tumors treatable with hyperthermia. In our institutional multidisciplinary team a pilot study has been designed in order to evaluate feasibility, outcome and toxicity of tri-modality treatment in pts with locally advanced cervical cancer in our daily practice. Since January 2003 to now eight patients affected by cervical cancer with stage IB2 through IVA N0-N+ pelvic or paraaortic were entered the study. Six patients were treated at initial diagnosis and two patients after chemotherapy which had achieved stable disease. Treatment regimen consisted in 5 courses of weekly chemotherapy (cisplatin 40 mg/mq) with concurrent external radiotherapy to a total dose of 64-66 Gy on CTV1 and 45 Gy on para-aortic nodes plus boost in pts with enlarged nodes identified by imaging. Five weekly sessions of hyperthermia were performed by using BSD 2000 system and sigma 60 applicator. No significant toxicity occurred and all of the patients completed tri-modality treatment in accordance with the study protocol. Seven pts experienced a complete clinical remission and one patient a partial remission as defined by clinical and imaging examinations. After four months from the end of the treatment a patient with Stage IIB bulky tumor plus one pelvic positive node who was in complete remission (Clinical examination, MRI and TAC-PET three months from the end of the treatment were negative for evidence of disease) developed a bleeding recto-vaginal fistula plus central pelvic necrosis for which an

  9. Advocacy for Benchmarking in the Nigerian Institute of Advanced ...

    African Journals Online (AJOL)

    FIRST LADY

    The second school of thought while maintaining the comparative feature presents benchmarking as a .... A perusal of the history of the Nigerian Institute of Advanced Legal Studies .... Conduction of user survey/market research to determine.

  10. Annual report 1991. Institute for Advanced Materials

    International Nuclear Information System (INIS)

    1992-01-01

    The Institute executed in 1991 the R and D programme on advanced materials of the Joint Research Centre and contributed to the programmes: reactor safety, radio-active waste management, fusion technology and safety, nuclear fuel and actinide research. The supplementary programme: Operation of the High Flux Reactor is presented in condensed form. A full report is published separately. (Author). refs., figs., tabs

  11. Critical decisions for older people with advanced dementia: a prospective study in long-term institutions and district home care

    NARCIS (Netherlands)

    Toscani, F.; Steen, J.T. van der; Finetti, S.; Giunco, F.; Pettenati, F.; Villani, D.; Monti, M.; Gentile, S.; Charrier, L.; Giulio, P. Di

    2015-01-01

    OBJECTIVE: To describe and compare the decisions critical for survival or quality of life [critical decisions (CDs)] made for patients with advanced dementia in nursing homes (NHs) and home care (HC) services. DESIGN: Prospective cohort study with a follow-up of 6 months. SETTING: Lombardy Region

  12. 2nd Hong Kong University of Science and Technology Jockey Club Institute for Advanced Study Program on High Energy Physics Conference

    CERN Document Server

    Prokofiev, Kirill; HKUST 2016; HKUST IAS Program on High Energy Physics Conference; Future of high energy physics : some aspects

    2017-01-01

    This book comprises 26 carefully edited articles with well-referenced and up-to-date material written by many of the leading experts. These articles originated from presentations and dialogues at the second HKUST Institute for Advanced Study Program on High Energy Physics are organized into three aspects, Theory, Accelerator, and Experiment, focusing on in-depth analyses and technical aspects that are essential for the developments and expectations for the future high energy physics.

  13. [The survival prediction model of advanced gallbladder cancer based on Bayesian network: a multi-institutional study].

    Science.gov (United States)

    Tang, Z H; Geng, Z M; Chen, C; Si, S B; Cai, Z Q; Song, T Q; Gong, P; Jiang, L; Qiu, Y H; He, Y; Zhai, W L; Li, S P; Zhang, Y C; Yang, Y

    2018-05-01

    Objective: To investigate the clinical value of Bayesian network in predicting survival of patients with advanced gallbladder cancer(GBC)who underwent curative intent surgery. Methods: The clinical data of patients with advanced GBC who underwent curative intent surgery in 9 institutions from January 2010 to December 2015 were analyzed retrospectively.A median survival time model based on a tree augmented naïve Bayes algorithm was established by Bayesia Lab software.The survival time, number of metastatic lymph nodes(NMLN), T stage, pathological grade, margin, jaundice, liver invasion, age, sex and tumor morphology were included in this model.Confusion matrix, the receiver operating characteristic curve and area under the curve were used to evaluate the accuracy of the model.A priori statistical analysis of these 10 variables and a posterior analysis(survival time as the target variable, the remaining factors as the attribute variables)was performed.The importance rankings of each variable was calculated with the polymorphic Birnbaum importance calculation based on the posterior analysis results.The survival probability forecast table was constructed based on the top 4 prognosis factors. The survival curve was drawn by the Kaplan-Meier method, and differences in survival curves were compared using the Log-rank test. Results: A total of 316 patients were enrolled, including 109 males and 207 females.The ratio of male to female was 1.0∶1.9, the age was (62.0±10.8)years.There was 298 cases(94.3%) R0 resection and 18 cases(5.7%) R1 resection.T staging: 287 cases(90.8%) T3 and 29 cases(9.2%) T4.The median survival time(MST) was 23.77 months, and the 1, 3, 5-year survival rates were 67.4%, 40.8%, 32.0%, respectively.For the Bayesian model, the number of correctly predicted cases was 121(≤23.77 months) and 115(>23.77 months) respectively, leading to a 74.86% accuracy of this model.The prior probability of survival time was 0.503 2(≤23.77 months) and 0.496 8

  14. The outcome and predictive factors of sunitinib therapy in advanced gastrointestinal stromal tumors (GIST) after imatinib failure - one institution study

    International Nuclear Information System (INIS)

    Rutkowski, Piotr; Osuch, Czesław; Mierzejewska, Ewa; Wasielewski, Kacper; Woźniak, Agnieszka; Grzesiakowska, Urszula; Nowecki, Zbigniew I; Siedlecki, Janusz A; Limon, Janusz; Bylina, Elżbieta; Klimczak, Anna; Świtaj, Tomasz; Falkowski, Sławomir; Kroc, Jacek; Ługowska, Iwona; Brzeskwiniewicz, Magdalena; Melerowicz, Wojciech

    2012-01-01

    Gastrointestinal stromal tumors (GIST) mutational status is recognized factor related to the results of tyrosine kinase inhibitors therapy such as imatinib (IM) or sunitinib (SU). Arterial hypertension (AH) is common adverse event related to SU, reported as predictive factor in renal cell carcinoma. The aim of the study was to analyze the outcomes and factors predicting results of SU therapy in inoperable/metastatic CD117(+) GIST patients after IM failure. We identified 137 consecutive patients with advanced inoperable/metastatic GIST treated in one center with SU (2 nd line treatment). Median follow-up time was 23 months. Additionally, in 39 patients there were analyzed selected constitutive single nucleotide polymorphisms (SNPs) of VEGFA and VEGFR2 genes. One year progression-free survival (PFS; calculated from the start of SU) rate was 42% and median PFS was 43 weeks. The estimated overall survival (OS, calculated both from start of SU or IM) was 74 weeks and 51 months, respectively. One-year PFS was 65% (median 74 weeks) in 55 patients with AH vs. 22% (median 17 weeks) in patients without AH. Patients with primary tumors carrying mutations in KIT exon 9 or wild-type had substantially better 1-year PFS (68% and 57%; median 65.5 and 50.5 weeks, respectively) than patients having tumors with KIT exon 11 or PDGFRA mutations (34% and 15%; median 36.8 and 9 weeks, respectively). We identified two independent factors with significant impact on PFS and OS in univariate and multivariate analysis: primary tumor genotype and presence of AH. The most common adverse events during therapy were: fatigue, AH, hypothyroidism, hand and foot syndrome, mucositis, skin reactions, dyspepsia, and diarrhea. Two deaths were assessed as related to tumor rupture caused by reaction to SU therapy. The presence of C-allele in rs833061 and the T-allele in rs3025039 polymorphism of VEGFA were associated with significantly higher risk of hypothyroidism (OR: 10.0 p = 0.041 and OR: 10.5; p = 0

  15. The outcome and predictive factors of sunitinib therapy in advanced gastrointestinal stromal tumors (GIST after imatinib failure - one institution study

    Directory of Open Access Journals (Sweden)

    Rutkowski Piotr

    2012-03-01

    Full Text Available Abstract Background Gastrointestinal stromal tumors (GIST mutational status is recognized factor related to the results of tyrosine kinase inhibitors therapy such as imatinib (IM or sunitinib (SU. Arterial hypertension (AH is common adverse event related to SU, reported as predictive factor in renal cell carcinoma. The aim of the study was to analyze the outcomes and factors predicting results of SU therapy in inoperable/metastatic CD117(+ GIST patients after IM failure. Methods We identified 137 consecutive patients with advanced inoperable/metastatic GIST treated in one center with SU (2nd line treatment. Median follow-up time was 23 months. Additionally, in 39 patients there were analyzed selected constitutive single nucleotide polymorphisms (SNPs of VEGFA and VEGFR2 genes. Results One year progression-free survival (PFS; calculated from the start of SU rate was 42% and median PFS was 43 weeks. The estimated overall survival (OS, calculated both from start of SU or IM was 74 weeks and 51 months, respectively. One-year PFS was 65% (median 74 weeks in 55 patients with AH vs. 22% (median 17 weeks in patients without AH. Patients with primary tumors carrying mutations in KIT exon 9 or wild-type had substantially better 1-year PFS (68% and 57%; median 65.5 and 50.5 weeks, respectively than patients having tumors with KIT exon 11 or PDGFRA mutations (34% and 15%; median 36.8 and 9 weeks, respectively. We identified two independent factors with significant impact on PFS and OS in univariate and multivariate analysis: primary tumor genotype and presence of AH. The most common adverse events during therapy were: fatigue, AH, hypothyroidism, hand and foot syndrome, mucositis, skin reactions, dyspepsia, and diarrhea. Two deaths were assessed as related to tumor rupture caused by reaction to SU therapy. The presence of C-allele in rs833061 and the T-allele in rs3025039 polymorphism of VEGFA were associated with significantly higher risk of hypothyroidism

  16. NATO Advanced Study Institute on Mixed-Valence Compounds : Theory and Applications in Chemistry, Physics, Geology, and Biology

    CERN Document Server

    1980-01-01

    It has been a decade since two seminal reviews demonstrated that mixed-valence compounds share many unique and fascinating features. The insight pro­ vided by those early works has promoted a great deal of both experimental and theoretical study. As a result of extensive efforts, our understanding of the bonding and properties of mixed-valence compounds has advanced substantially. There has been no compre­ hensive treatment of mixed-valence compounds since 1967, and the meeting convened at Oxford in September, 1979, provided a unique opportunity to examine the subject and its many ramifications. Mixed-valence compounds play an important role in many fields. Although the major impact of the subject has been in chemistry, its importance has become increasingly clear in solid state physics, geology, and biology. Extensive interest and effort in the field of molecular metals has demonstrated that mixed-valency is a prerequisite for high elec­ trical conductivity. The intense colors of many minerals have been s...

  17. Correlation between vitiligo occurrence and clinical benefit in advanced melanoma patients treated with nivolumab: A multi-institutional retrospective study.

    Science.gov (United States)

    Nakamura, Yasuhiro; Tanaka, Ryota; Asami, Yuri; Teramoto, Yukiko; Imamura, Taichi; Sato, Sayuri; Maruyama, Hiroshi; Fujisawa, Yasuhiro; Matsuya, Taisuke; Fujimoto, Manabu; Yamamoto, Akifumi

    2017-02-01

    Vitiligo is occasionally seen in melanoma patients. Although several studies indicate a correlation between vitiligo occurrence and clinical response in melanoma patients receiving immunotherapy, most studies have included heterogeneous patient and treatment settings. The aim of this study is to investigate the correlation between the occurrence of vitiligo and clinical benefit of nivolumab treatment in advanced melanoma patients. We retrospectively reviewed unresectable stage III or IV melanoma patients treated with nivolumab. Of 35 melanoma patients treated with nivolumab, 25.7% (9/35) developed vitiligo during treatment. The time from the start of nivolumab treatment to occurrence of vitiligo ranged 2-9 months (mean, 5.2). Of nine patients who developed vitiligo, two (22.2%) had a complete response to nivolumab and two (22.2%) had a partial response. The objective response rate was significantly higher in patients with vitiligo than in patients without vitiligo (4/9 [44.4%] vs 2/26 [7.7%]; P = 0.027). The mean time to vitiligo occurrence in patients achieving an objective response was significantly less than that in patients who showed no response (3.1 vs 6.8 months, P = 0.004). Vitiligo occurrence was significantly associated with prolonged progression-free and overall survival (hazard ratio, 0.24 and 0.16; 95% confidence interval, 0.11-0.55 and 0.03-0.79; P = 0.005, and 0.047, respectively). At the 20-week landmark analysis, however, vitiligo was not associated with a statistically significant overall survival benefit (P = 0.28). The occurrence of vitiligo during nivolumab treatment may be correlated with favorable clinical outcome. © 2016 Japanese Dermatological Association.

  18. Research Institute for Advanced Computer Science

    Science.gov (United States)

    Gross, Anthony R. (Technical Monitor); Leiner, Barry M.

    2000-01-01

    The Research Institute for Advanced Computer Science (RIACS) carries out basic research and technology development in computer science, in support of the National Aeronautics and Space Administration's missions. RIACS is located at the NASA Ames Research Center. It currently operates under a multiple year grant/cooperative agreement that began on October 1, 1997 and is up for renewal in the year 2002. Ames has been designated NASA's Center of Excellence in Information Technology. In this capacity, Ames is charged with the responsibility to build an Information Technology Research Program that is preeminent within NASA. RIACS serves as a bridge between NASA Ames and the academic community, and RIACS scientists and visitors work in close collaboration with NASA scientists. RIACS has the additional goal of broadening the base of researchers in these areas of importance to the nation's space and aeronautics enterprises. RIACS research focuses on the three cornerstones of information technology research necessary to meet the future challenges of NASA missions: (1) Automated Reasoning for Autonomous Systems. Techniques are being developed enabling spacecraft that will be self-guiding and self-correcting to the extent that they will require little or no human intervention. Such craft will be equipped to independently solve problems as they arise, and fulfill their missions with minimum direction from Earth; (2) Human-Centered Computing. Many NASA missions require synergy between humans and computers, with sophisticated computational aids amplifying human cognitive and perceptual abilities; (3) High Performance Computing and Networking. Advances in the performance of computing and networking continue to have major impact on a variety of NASA endeavors, ranging from modeling and simulation to data analysis of large datasets to collaborative engineering, planning and execution. In addition, RIACS collaborates with NASA scientists to apply information technology research to a

  19. Institute for Advanced Learning and Research names new executive director

    OpenAIRE

    Virginia Tech News

    2008-01-01

    Virginia Tech's Institute for Advanced Learning and Research has named Liam E. Leightley as executive director, effective Oct. 6, 2008, according to Mike Henderson, chair of the institute's board of trustees.

  20. Radiation Protection in Medical Physics : Proceedings of the NATO Advanced Study Institute on Radiation Protection in Medical Physics Activities

    CERN Document Server

    Lemoigne, Yves

    2011-01-01

    This book introduces the fundamental aspects of Radiation Protection in Medical Physics and covers three main themes: General Radiation Protection Principles; Radiobiology Principles; Radiation Protection in Hospital Medical Physics. Each of these topics is developed by analysing the underlying physics principles and their implementation, quality and safety aspects, clinical performance and recent advances in the field. Some issues specific to the individual techniques are also treated, e.g. calculation of patient dose as well as that of workers in hospital, optimisation of equipment used, shielding design of radiation facilities, radiation in oncology such as use of brachytherapy in gynecology or interventional procedures. All topics are presented with didactical language and style, making this book an appropriate reference for students and professionals seeking a comprehensive introduction to the field as well as a reliable overview of the most recent developments.

  1. Institutional transformation: An analysis of change initiatives at NSF ADVANCE institutions

    Science.gov (United States)

    Plummer, Ellen W.

    The purpose of this study was to examine how institutional culture promoted or impeded the implementation of round one and two NSF ADVANCE initiatives designed to improve academic climates for women in science and engineering. This study was conducted in two phases. In phase one, 35 participants from 18 institutions were interviewed to answer three research questions. Participants identified a policy, process, or program designed to improve academic cultures for women in science and engineering fields. Participants also identified strategies that promoted the implementation of these efforts, and discussed factors that impeded these efforts. In phase two, site visits were conducted at two institutions to answer a fourth research question. How did institutional culture shape the design and implementation of faculty search processes? Policies, processes, and programs were implemented by participants at the institutional, departmental, and individual levels and included family friendly and dual career policies at the institutional level, improved departmental faculty search and climate improvement processes, and mentoring programs and training for department heads at the individual level. Communication and leadership strategies were key to the successful implementation of policies, processes, and programs designed to achieve institutional transformation. Communication strategies involved shaping change messages to reach varied audiences often with the argument that change efforts would improve the climate for everyone not just women faculty members. Administrative and faculty leaders from multiple levels proved important to change efforts. Institutional Transformation Institutional culture shaped initiatives to improve faculty search processes. Faculty leaders in both settings used data to persuade faculty members of the need for change. At one site, data that included national availability information was critical to advancing the change agenda. At the other site

  2. NATO Advanced Study Institute and Séminaire de mathématiques supérieures on Fractal Geometry and Analysis

    CERN Document Server

    Dubuc, Serge

    1991-01-01

    This ASI- which was also the 28th session of the Seminaire de mathematiques superieures of the Universite de Montreal - was devoted to Fractal Geometry and Analysis. The present volume is the fruit of the work of this Advanced Study Institute. We were fortunate to have with us Prof. Benoit Mandelbrot - the creator of numerous concepts in Fractal Geometry - who gave a series of lectures on multifractals, iteration of analytic functions, and various kinds of fractal stochastic processes. Different foundational contributions for Fractal Geometry like measure theory, dy­ namical systems, iteration theory, branching processes are recognized. The geometry of fractal sets and the analytical tools used to investigate them provide a unifying theme of this book. The main topics that are covered are then as follows. Dimension Theory. Many definitions of fractional dimension have been proposed, all of which coincide on "regular" objects, but often take different values for a given fractal set. There is ample discussion ...

  3. NATO Advanced Study Institute on Engineering of Crystalline Materials Properties : State of the Art in Modeling Design and Applications. New Materials for better Defence and Security

    CERN Document Server

    Braga, Dario; Addadi, Lia

    2008-01-01

    This volume collects the lecture notes (ordered alphabetically according to the first author surname) of the talks delivered by the main speakers at the Erice 2007 International School of Crystallography, generously selected by NATO as an Advanced Study Institute (# 982582). The aim of the school was to discuss the state-of-the-art in molecular materials design, that is, the rational analysis and fabrication of crystalline solids showing a predefined structural organization of their component molecules and ions, which results in the manifestation of a specific collective property of technological interest. The School was held on June 7–17, 2007, in Erice (an old town, over 3000 years, located on the top of a Sicilian hill that oversees the sea near Trapani). The school developed following two parallel lines. First we established “where we are” in terms of modelling, design, synthesis and applications of crystalline solids with predefined properties. Second, we attempted to define current and possible fu...

  4. Irradiation Facilities of the Takasaki Advanced Radiation Research Institute

    Directory of Open Access Journals (Sweden)

    Satoshi Kurashima

    2017-03-01

    Full Text Available The ion beam facility at the Takasaki Advanced Radiation Research Institute, the National Institutes for Quantum and Radiological Science and Technology, consists of a cyclotron and three electrostatic accelerators, and they are dedicated to studies of materials science and bio-technology. The paper reviews this unique accelerator complex in detail from the viewpoint of its configuration, accelerator specification, typical accelerator, or irradiation technologies and ion beam applications. The institute has also irradiation facilities for electron beams and 60Co gamma-rays and has been leading research and development of radiation chemistry for industrial applications in Japan with the facilities since its establishment. The configuration and utilization of those facilities are outlined as well.

  5. Concomitant pelvic irradiation and chemotherapy in locally advanced cervical carcinoma. A retrospective study of 92 patients treated at the Curie Institute

    International Nuclear Information System (INIS)

    Nguyen, D.; Rochefordiere, A. de la; Chauveinc, L.; Cosset, J.M.; Clough, K.B.; Mouret-Fourme, E.; Guyonnet, M.

    2002-01-01

    The prognosis of locally advanced cervix cancers is poor with metastatic and local recurrence risks. Recent publications reported that concurrent chemotherapy and pelvic radiation increased local control compared to radiotherapy alone. Chemotherapy could also decrease metastatic recurrences. We report 92 cases of patients with locally advanced cervix cancer treated between 1986 and 1998 at the Institut Curie. Patients and methods. - Concurrent chemo-radiation was exclusive in 51 cases and added to surgery in 41 cases. Chemotherapy with 5FU -Cisplatin-Mitomycin C-Vindesin (protocol A) was performed for 43% of patients and 57% of them received 5FU-Cisplatin alone (protocol B). Results. -Median follow-up was 64 months (6-149 months). Five-year disease-free survival rate was 47% and local control rate was 70%. Disease-free survival was correlated with therapeutic response. After exclusive chemo-radiation, the good responsive patients had a better DFS (54% vs 26%, p=0.018). In the surgery group, those patients with sterilized lymph nodes and tumours had also a higher DFS (76% vs 47%, p=0.036). Toxicity was higher with protocol A. Conclusion. - From our study, it appears that local control of advanced cervix cancers is better with combined chemoradiotherapy but disease-free survival stays low according to the metastatic evolution. Metastasis without local recurrence remained frequent in our study. 5FU-CDDP chemotherapy has a lower toxicity and is as effective as 5FU-CDDP-Mitomycin C-Vindesin protocol, in association with radiotherapy. (author)

  6. NATO Advanced Study Institute on Low-dimensional Cooperative Phenomena : the Possibility of High-Temperature Superconductivity

    CERN Document Server

    1975-01-01

    Theoretical and experimental work on solids with low-dimensional cooperative phenomena has been rather explosively expanded in the last few years, and it seems to be quite fashionable to con­ tribute to this field, especially to the problem of one-dimensional metals. On the whole, one could divide the huge amount of recent investigations into two parts although there is much overlap bet­ ween these regimes, namely investigations on magnetic exchange interactions constrained to mainly one or two dimensions and, secondly, work done on Id metallic solids or linear chain compounds with Id delocalized electrons. There is, of course, overlap from one extreme case to the other with these solids and in some rare cases both phenomena are studied on one and the same crystal. In fact, however, most of the scientific groups in this area could be associated roughly with one of these categories and,in addition, a separation between theoreticians and experimentalists in each of these groups leads to a further splitting of...

  7. Institute for the advancement of Calvinism

    Directory of Open Access Journals (Sweden)

    J. J. Snyman

    1977-03-01

    Full Text Available This publication presents all the papers read at a conference held at the Potchefstroom University for Christian Higher Education during September 1975. The theme of the conference (initiated by Prof. HJJ . Bingle, at the time rector of the PU for CHE was formulated as “ Reformed Institutions for Higher Education as a Bulwark for the Kingdom of God — present and future”. The idea of such institutions as a “bulwark for the Kingdom of God" is toned down in the title of this book. The difference in tone may be explained as the result of the difference between a stage of planning and a stage of looking back on what was carried out of that planning. Such a re­ view of this enterprise cannot be unaccompanied by the feelings of being “sadder but wiser” . Something of this is reflected in the prefatory notes of Prof. Bingle to this book. Experiences of the conference came to be com­ mitted to paper in this publication and Prof. Bingle remarks very aptly amongst other things that this collection of conference papers reveals a probable “identification of important differences of opinion on Christian Higher Education.” But if this insight meant a revision of the idea of in­ stitutions for Christian higher education as “bulwarks for the Kingdom of God”, this publication also serves to put on record another experience of the conference: “that there are encouraging signs -of a will to find one another in our common pursuit of an honest appraisal of the Christian principle in higher education”. These proceedings may be viewed (in the words of Prof. Bingle as a valuable expression and documentation of an “attem pt at ecumenicity within the context of Christian Higher Educa tion” .

  8. A Brief Examination of Institutional Advancement Activities at Hispanic Serving Institutions.

    Science.gov (United States)

    Mulnix, Michael William; Bowden, Randall G.; Lopez, Esther Elena

    2002-01-01

    Examined what level of importance university presidents of Hispanic serving institutions place on institutional advancement. Found that they believe strongly in the importance of such activities but most believe their efforts in areas such as fund raising, marketing, and public relations are not very satisfactory. Also found that many do not…

  9. Studying institutional work in organizations

    DEFF Research Database (Denmark)

    Bjerregaard, Toke

    2011-01-01

    Purpose – In order to provide new and other directions to institutional studies in organization theory, Lawrence and Suddaby forward the notion of institutional work of actors aimed at maintaining, changing and disrupting institutions. The purpose of this paper is to further theory and method...... in studying the institutional work of people in organizations. Design/methodology/approach – Methodological insights from the ways in which theories of human agency in institutional contexts have co-evolved with field study methodologies are analyzed in related fields of research, particularly in sociology...... and anthropology. Findings – The ways have been analyzed in which social theories of human agency in institutional contexts and field methodology have co-evolved in an inter-disciplinary perspective. The analysis shows how field methodologies may provide inspirations to theory and method in studying institutional...

  10. Institutional quality and income inequality in the advanced countries

    Directory of Open Access Journals (Sweden)

    Josifidis Kosta

    2017-01-01

    Full Text Available The purpose of this paper is to shed more light on the effects of changes in quality of economic, legal and political institutions on income inequality in the advanced countries over the last two decades. Using the robust panel model on a sample of 21 OECD countries, it is found that the impact of elitization of society is more pronounced than the impact of unionization on income redistribution, but both effects are less expressed in comparison to the influence of institutional changes on redistribution. In a globalized economy, insufficient redistribution and high inequality might be interpreted as the consequence of institutional inertia to disruptive technological and business changes.

  11. The Advanced Technology Environmental Education Center Summer Fellows Institute.

    Science.gov (United States)

    Depken, Diane E.; Zeman, Catherine L.; Lensch, Ellen Kabat; Brown, Edward J.

    2002-01-01

    Describes the background, activities, and outcomes of the Advanced Technology Environmental Education Center (ATEEC) and its Summer Fellows Institutes as a model for disciplinary and cross-disciplinary infusion of environmental science and technology content, curriculum, and methods into the classroom. Presents experiences, themes, and activities…

  12. NATO Advanced Research Institute on the Efficiency of Manufacturing Systems

    CERN Document Server

    Berg, C; French, D

    1983-01-01

    The Advanced Research Institute (A.R. 1.) on "the efficiency of Manufacturing Systems" was held under the auspices of the NATO Special Programm~ Panel on Systems Science as a part of the NATO Science Committee's continuous effort to promote the advancement of science through international co-operation. Advanced Research Institutes are organised for the purpose of bringing together experts in a particular field of interest to identify and make known the present state of knowledge in that area and, through informed debate, to make recommendations for directions for future research that would benefit the community at large. To this end two kinds of contribution were obtained by invitation. There were those papers which were about the current state of work in the area of manufacturing systems and its organisation; in addition three theme papers were presented to provide a stimulus to the discussion in terms of ways of thinking, both about the area and about the kind of research needed.

  13. Advancing methods for research on household water insecurity: Studying entitlements and capabilities, socio-cultural dynamics, and political processes, institutions and governance.

    Science.gov (United States)

    Wutich, Amber; Budds, Jessica; Eichelberger, Laura; Geere, Jo; Harris, Leila; Horney, Jennifer; Jepson, Wendy; Norman, Emma; O'Reilly, Kathleen; Pearson, Amber; Shah, Sameer; Shinn, Jamie; Simpson, Karen; Staddon, Chad; Stoler, Justin; Teodoro, Manuel P; Young, Sera

    2017-11-01

    Household water insecurity has serious implications for the health, livelihoods and wellbeing of people around the world. Existing methods to assess the state of household water insecurity focus largely on water quality, quantity or adequacy, source or reliability, and affordability. These methods have significant advantages in terms of their simplicity and comparability, but are widely recognized to oversimplify and underestimate the global burden of household water insecurity. In contrast, a broader definition of household water insecurity should include entitlements and human capabilities, sociocultural dynamics, and political institutions and processes. This paper proposes a mix of qualitative and quantitative methods that can be widely adopted across cultural, geographic, and demographic contexts to assess hard-to-measure dimensions of household water insecurity. In doing so, it critically evaluates existing methods for assessing household water insecurity and suggests ways in which methodological innovations advance a broader definition of household water insecurity.

  14. Advanced Chemical Propulsion Study

    Science.gov (United States)

    Woodcock, Gordon; Byers, Dave; Alexander, Leslie A.; Krebsbach, Al

    2004-01-01

    A study was performed of advanced chemical propulsion technology application to space science (Code S) missions. The purpose was to begin the process of selecting chemical propulsion technology advancement activities that would provide greatest benefits to Code S missions. Several missions were selected from Code S planning data, and a range of advanced chemical propulsion options was analyzed to assess capabilities and benefits re these missions. Selected beneficial applications were found for higher-performing bipropellants, gelled propellants, and cryogenic propellants. Technology advancement recommendations included cryocoolers and small turbopump engines for cryogenic propellants; space storable propellants such as LOX-hydrazine; and advanced monopropellants. It was noted that fluorine-bearing oxidizers offer performance gains over more benign oxidizers. Potential benefits were observed for gelled propellants that could be allowed to freeze, then thawed for use.

  15. Institute for fusion studies

    International Nuclear Information System (INIS)

    1982-01-01

    Theoretical discussions were presented for each of the following topics: (1) review of linear microinstabilities; (2) nonlinear drift wave in a sheared magnetic field; (3) electrostatic fluctuation measurements in tokamaks and other toroidal experiments; (4) microinstability, entropy production, and plasma confinement; (5) measurements of tokamak edge fluctuations and transport; (6) nonlinear gyrokinetic equations for low-frequency electromagnetic waves in general plasma equilibria; (7) nonlinear electron response to drift wave fluctuations in toroidal geometry; (8) universal mode with diffusive electrons; (9) low-frequency magnetic instabilities and diffusion; (10) nonlinear study of drift wave turbulence; (11) turbulent spectra from the interaction of three drift waves; (12) lower hybrid drift instability; (13) lower-hybrid-drift turbulence and anomalous transport; (14) simulation of drift-cone turbulence in a neutral-beam driven mirror machine; (15) drift wave solitons and turbulence; (16) nonlinear behavior of unstable toroidally induced drift modes in tokamak geometry; (17) microturbulence in PLT; (18) collisional drift instability; (19) two-point correlation for trapped electrons and the frequency spectrum of drift wave turbulence in tokamaks; (20) density fluctuations in PDX and Oleator C; (21) kinetic theory of ballooning mode; (22) electromagnetic kinetic toroidal eigenmodes for general MHD equilibria; (23) particle simulation of the drift wave including the electromagnetic effect; and (24) anomalous ion thermal conductivity

  16. Advanced Propulsion Study

    National Research Council Canada - National Science Library

    Davis, Eric

    2004-01-01

    ... that show promise of leading to a major advance in Earth-to-orbit (ETO) propulsion. The study also reviewed and evaluated a select number of credible far-term breakthrough propulsion physics concepts pertaining...

  17. National Advanced Drilling and Excavation Technologies Institute. Status report, March 1997

    Energy Technology Data Exchange (ETDEWEB)

    Peterson, C.

    1997-12-31

    The National Advanced Drilling and Excavation Technologies (NADET) program is intended to pool support, talent, and technologies of the industries dependent upon drilling and excavation technologies to initiate, coordinate, and sustain programs capable of developing substantial technological advances. The NADET Institute has been funded by the DOE Office of Geothermal Technologies and is now supporting seven projects aimed at advanced geothermal drilling technologies. The Institute seeks to broaden its base of funding and technological support from both government and industry sources. Encouraging progress has been made with the support of dues-paying industrial members and industrial sponsorship of a substantial drilling research study.

  18. Earth Institute at Columbia University ADVANCE Program: Addressing Needs for Women in Earth and Environmental Sciences

    Science.gov (United States)

    Bell, R. E.; Cane, M.; Mutter, J.; Miller, R.; Pfirman, S.; Laird, J.

    2004-12-01

    The Earth Institute has received a major NSF ADVANCE grant targeted at increasing the participation and advancement of women scientists and engineers in the Academy through institutional transformation. The Earth Institute at Columbia University includes 9 research institutes including Lamont-Doherty Earth Observatory, Center for Environmental Research and Conservation (CERC), Center for International Earth Science Information Network (CIESIN), International Research Institute (IRI) for Climate Prediction, Earth Engineering Center, NASA-Goddard Institute for Space Studies, Center for Risks and Hazards, Center for Globalization and Sustainable Development, and Center for Global Health and Economic Development and six academic departments including Ecology, Evolution and Environmental Biology (E3B, School of Arts and Sciences), Earth and Environmental Engineering (DEEE, School of Engineering and Applied Sciences), Department of Environmental Health (School of Public Health), Department of Earth and Environmental Sciences (DEES, School of Arts and Sciences), Department of International and Public Affairs (School of International and Policy Affairs), and Barnard College Department of Environmental Science. The Earth Institute at Columbia University's ADVANCE program is based both on a study of the status of women at Columbia and research on the progression of women in science elsewhere. The five major targets of the Columbia ADVANCE program are to (1) change the demographics of the faculty through intelligent hiring practices, (2) provide support to women scientists through difficult life transitions including elder care and adoption or birth of a child, (3) enhance mentoring and networking opportunities, (4) implement transparent promotion procedures and policies, and (5) conduct an institutional self study. The Earth Institute ADVANCE program is unique in that it addresses issues that tend to manifest themselves in the earth and environmental fields, such as extended

  19. NATO Advanced Research Institute on Health Services Systems

    CERN Document Server

    Werff, Albert; Hirsch, Gary; Barnard, Keith

    1984-01-01

    The Advanced Research Institute on "Health Services Systems" was held under the auspices of the NATO Special Programme Panel on Systems Science as a part of the NATO Science Committee's continuous effort to promote the advancement of science through international cooperation. A special word is said in this respect supra by Pro­ fessor Checkland, Chairman of the Systems Science Panel. The Advanced Research Institute (ARI) was organized for the purpose of bringing together senior scientists to seek a consensus on the assessment of the present state of knowledge on the specific topic of "health services systems" and to present views and recom­ mendations for future health services research directions, which should be of value to both the scientific community and the people in charge of reorienting health services. The conference was structured so as to permit the assembly of a variety of complementary viewpoints through intensive group discussions to be the basis of this final report. Invitees were selected fr...

  20. TTI Phase 2 Institutional Support: Indian Institute of Dalit Studies ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    This funding will enhance the Indian Institute of Dalit Studies' (IIDS) role as a credible public policy institution in India by strengthening its ability to provide high-quality, influential, and policy-relevant research. About the Indian Institute of Dalit Studies IIDS is a social sciences research centre with a focus on development ...

  1. Institutional Repositories in Indian Universities and Research Institutes: A Study

    Science.gov (United States)

    Krishnamurthy, M.; Kemparaju, T. D.

    2011-01-01

    Purpose: The purpose of this paper is to report on a study of the institutional repositories (IRs) in use in Indian universities and research institutes. Design/methodology/approach: Repositories in various institutions in India were accessed and described in a standardised way. Findings: The 20 repositories studied covered collections of diverse…

  2. Advancing the Payments for Ecosystem Service Discourse through Institutional Theory

    DEFF Research Database (Denmark)

    Jespersen, Kristjan

    by drawing insights from the institutional theory literature. Comprised of a meta-analysis literature review, two case studies and a contextual theory-driven paper, the findings are applicable for both PES scholars and practitioners. By engaging in this new perspective, PES scholars and practitioners......My research interest centers on payments for ecosystem services (PES), a prominent strategy to address economic externalities of resource extraction and commodity processing, improving both social and ecological outcomes. Given the novelty of these kinds of institutions, my research uses them...... as a set of compelling cases for studying institutional creation, and my driving research question is “How are institutions in support of PES created?” Importantly, my research spans environmental economics and business studies to study how PES schemes might more fully incorporate the private sector...

  3. NATO Advanced Research Institute on Search Theory and Applications

    CERN Document Server

    Stone, Lawrence

    1980-01-01

    The NATO Advanced Research Institute on Search Theory and Appli­ cations was held at the Hotel Algarve in Praia Da Rocha, Portugal, from March 26 through March 30, 1979, and was sponsored by the NATO Special Programme Panel on Systems Science. There were forty-one participants representing a wide range of backgrounds and interests. The purpose of the institute was to bring together people working in search theory and applications with potential users of search techniques to stimulate the increased application of recent­ ly developed search technology to civilian problems such as search and rescue, mineral exploration, surveillance, and fishing. Con­ versely, it was felt that by exposing search analysts to potential applications and new problems, they would be stimulated to develop new techniques for these applications and problems. The exchange of ideas and problems necessary to accomplish these goals was provided in the meeting workshops. There were three workshops, Search and Rescue, Exploration, and Sur...

  4. NDEA Institute for Advanced Study in Industrial Arts. (Detroit, June 24-August 2, 1968). Final Report. Integration of Fluid Power Instruction into Energy and Propulsion Systems.

    Science.gov (United States)

    Cochran, Leslie H.; Wolansky, William D.

    The institute was designed to provide industrial arts teachers with updating experiences in fluid power education. It had four educational phases: technical instruction, directed field experiences, teaching strategies, and professional development. The latter involved meeting with participants in two other institutes. Twenty-one participants were…

  5. The Community College President: Working with and through the Media to Advance the Institution

    Science.gov (United States)

    Carringer, Paul T.

    2013-01-01

    The purpose of this study was to examine how community college presidents successfully work with and through the media to advance their institutions. Four successful cases were studied. These success stories came from the list of Paragon Award winners selected annually by the National Council of Marketing and Public Relations (NCMPR) and be cross…

  6. Employee Perceptions on Recognition and Opportunity for Advancement: The Case of a Financial Institution in Ghana

    OpenAIRE

    Veronica Adu-Brobbey

    2014-01-01

    Recognition and opportunity for advancement are facets of motivation that affect employee satisfaction at the workplace. For management to adequately attend to these, there is the need to know how the employees themselves feel about such issues. This study was conducted to assess the perceptions of employees of a financial institution in Ghana regarding recognition and opportunity for advancement. Survey with questionnaire and interview were used to collect data from 61 employees. Descriptive...

  7. Institutional total energy case studies

    Energy Technology Data Exchange (ETDEWEB)

    Wulfinghoff, D.

    1979-07-01

    Profiles of three total energy systems in institutional settings are provided in this report. The plants are those of Franciscan Hospital, a 384-bed facility in Rock Island, Illinois; Franklin Foundation Hospital, a 100-bed hospital in Franklin, Louisiana; and the North American Air Defense Command Cheyenne Mountain Complex, a military installation near Colorado Springs, Colorado. The case studies include descriptions of plant components and configurations, operation and maintenance procedures, reliability, relationships to public utilities, staffing, economic efficiency, and factors contributing to success.

  8. Advanced Collaborative Emissions Study (ACES)

    Energy Technology Data Exchange (ETDEWEB)

    Greenbaum, Daniel; Costantini, Maria; Van Erp, Annemoon; Shaikh, Rashid; Bailey, Brent; Tennant, Chris; Khalek, Imad; Mauderly, Joe; McDonald, Jacob; Zielinska, Barbara; Bemis, Jeffrey; Storey, John; Hallberg, Lance; Clark, Nigel

    2013-12-31

    The objective of the Advanced Collaborative Emissions Study (ACES) was to determine before widespread commercial deployment whether or not the new, energy-efficient, heavy duty diesel engines (2007 and 2010 EPA Emissions Standards Compliant) may generate anticipated toxic emissions that could adversely affect the environment and human health. ACES was planned to take place in three phases. In Phase 1, extensive emissions characterization of four production-intent prototype engine and control systems designed to meet 2007 standards for nitrogen oxides (NOx) and particulate matter (PM) was conducted at an existing emissions characterization facility: Southwest Research Institute (SwRI). One of the tested engines was selected (at random, after careful comparison of results) for health testing in Phase 3. In Phase 2, extensive emission characterization of three production-intent prototype engine and control systems meeting the 2010 standards (including more advanced NOx controls to meet the more stringent 2010 NOx standards) was conducted at the same test facility. In Phase 3, one engine/aftertreatment system selected from Phase 1 was further characterized during health effects studies (at an existing inhalation toxicology laboratory: Lovelace Respiratory Research Institute, [LRRI]) to form the basis of the ACES safety assessment. The Department of Energy (DOE) award provided funding for emissions characterization in Phases 1 and 2 as well as exposure characterization in Phase 3. The main health analyses in Phase 3 were funded separately and are not reported here.

  9. Fusion advanced studies Torus

    International Nuclear Information System (INIS)

    2007-01-01

    The successful development of ITER and DEMO scenarios requires preparatory activities on devices that are smaller than ITER, sufficiently flexible and capable of investigating the peculiar physics of burning plasma conditions. The aim of the Fusion Advanced Studies Torus (FAST) proposal [2.1] (formerly FT3 [2.2]) is to show that the preparation of ITER scenarios and the development of new expertise for the DEMO design and RD can be effectively implemented on a new facility. FAST will a) operate with deuterium plasmas, thereby avoiding problems associated with tritium, and allow investigation of nonlinear dynamics (which are important for understanding alpha particle behaviour in burning plasmas) by using fast ions accelerated by heating and current drive systems; b) work in a dimensionless parameter range close to that of ITER; c) test technical innovative solutions, such as full-tungsten plasma-facing components and an advanced liquid metal divertor target for the first wall/divertor, directly relevant for ITER and DEMO; d) exploit advanced regimes with a much longer pulse duration than the current diffusion time; e) provide a test bed for ITER and DEMO diagnostics; f) provide an ideal framework for model and numerical code benchmarks, their verification and validation in ITER/ DEMO-relevant plasma conditions

  10. Weekly Low-Dose Docetaxel-Based Chemoradiotherapy for Locally Advanced Oropharyngeal or Hypopharyngeal Carcinoma: A Retrospective, Single-Institution Study

    International Nuclear Information System (INIS)

    Fukada, Junichi; Shigematsu, Naoyuki; Takeda, Atsuya; Ohashi, Toshio; Tomita, Toshiki; Shiotani, Akihiro; Kunieda, Etsuo; Kawaguchi, Osamu; Fujii, Masato; Kubo, Atsushi

    2010-01-01

    Purpose: To retrospectively assess the efficacy, toxicity, and prognostic factors of weekly low-dose docetaxel-based chemoradiotherapy for Stage III/IV oropharyngeal or hypopharyngeal carcinoma. Methods and Materials: Between 2001 and 2005, 72 consecutive patients with locally advanced oropharyngeal or hypopharyngeal carcinoma were treated with concurrent chemoradiotherapy (CCR; radiation at 60 Gy plus weekly docetaxel [10 mg/m 2 ]). Thirty of these patients also received neoadjuvant chemotherapy (NAC; docetaxel, cisplatin, and 5-fluorouracil) before concurrent chemoradiotherapy. Survival was calculated according to the Kaplan-Meier method. The prognostic factors were evaluated by univariate and multivariate analyses. Results: The median follow-up was 33 months, with overall survival, disease-free survival, and locoregional control rates at 3 years of 59%, 45%, and 52%, respectively. Thirty-six patients (50%) experienced more than one Grade 3 to 4 acute toxicity. Grade 3 mucositis occurred in 32 patients (44%), Grade 4 laryngeal edema in 1 (1%). Grade ≥3 severe hematologic toxicity was observed in only 2 patients (3%). Grade 3 dysphagia occurred as a late complication in 2 patients (3%). Multivariate analyses identified age, T stage, hemoglobin level, and completion of weekly docetaxel, but not NAC, as significant factors determining disease-free survival. Conclusions: Docetaxel is an active agent used in both concurrent and sequential chemoradiotherapy regimens. Mucositis was the major acute toxicity, but this was well tolerated in most subjects. Anemia was the most significant prognostic factor determining survival. Further studies are warranted to investigate the optimal protocol for integrating docetaxel into first-line chemoradiotherapy regimens, as well as the potential additive impact of NAC.

  11. Exploring the Composite Trace of Research Outputs of Humanities and Social Sciences Scholars: A Case Study of the Institute for Advanced Studies in Humanities and Social Sciences at National Taiwan University

    Directory of Open Access Journals (Sweden)

    Kuang-Hua Chen

    2014-12-01

    Full Text Available In this study, we used the citation data from four databases (THCI, ACI, WOS and Scopus and one social media, Mendeley, to examine the composite traces of humanities and social sciences scholars’ research outputs. Using the researchers of the Institute for Advanced Studies in Humanities and Social Sciences in National Taiwan University as subjects, this study compared how the scholars’ publications were cited in Taiwan’s and international academic journals as well as used in the social Web. It found that most of the subjects’ publications were in Chinese, and the impact of the publications was domestic rather than international. Taiwan’s citation databases, unsurprisingly, saw more citations to their research outputs. However, when only the English publications were observed, it was found that the citation performances in international databases and Mendeley were highly correlated. This suggests that Mendeley is a valid altmetric citation source for observing the international impact of Taiwan’s scholars. [Article content in Chinese

  12. NATO-Advances Study Institute, Diamond and Diamond-Like Films and Coatings, Held in Il Ciocco, Castelvecchio Pascoli, Italy on July 22-August 3, 1990

    Science.gov (United States)

    1990-08-03

    39-690021279 FAX: 39-690021243 Dr. Alessandro Bellone Olivetti Office Via Jervis 20 10015 Ivres (Turin), Italy Phone: FAX: 39-125528116 Mr. Antonio...delle Volta , 94 1-25129 Bresua, Italy Phone: 39-30-347491 FAX: 39-30-342906 Prof. Masao Murakawa Nippon Institute of Technology 4-1 Gakuendai Miyashiro

  13. Activities of the Research Institute for Advanced Computer Science

    Science.gov (United States)

    Oliger, Joseph

    1994-01-01

    The Research Institute for Advanced Computer Science (RIACS) was established by the Universities Space Research Association (USRA) at the NASA Ames Research Center (ARC) on June 6, 1983. RIACS is privately operated by USRA, a consortium of universities with research programs in the aerospace sciences, under contract with NASA. The primary mission of RIACS is to provide research and expertise in computer science and scientific computing to support the scientific missions of NASA ARC. The research carried out at RIACS must change its emphasis from year to year in response to NASA ARC's changing needs and technological opportunities. Research at RIACS is currently being done in the following areas: (1) parallel computing; (2) advanced methods for scientific computing; (3) high performance networks; and (4) learning systems. RIACS technical reports are usually preprints of manuscripts that have been submitted to research journals or conference proceedings. A list of these reports for the period January 1, 1994 through December 31, 1994 is in the Reports and Abstracts section of this report.

  14. [Activities of Research Institute for Advanced Computer Science

    Science.gov (United States)

    Gross, Anthony R. (Technical Monitor); Leiner, Barry M.

    2001-01-01

    The Research Institute for Advanced Computer Science (RIACS) carries out basic research and technology development in computer science, in support of the National Aeronautics and Space Administrations missions. RIACS is located at the NASA Ames Research Center, Moffett Field, California. RIACS research focuses on the three cornerstones of IT research necessary to meet the future challenges of NASA missions: 1. Automated Reasoning for Autonomous Systems Techniques are being developed enabling spacecraft that will be self-guiding and self-correcting to the extent that they will require little or no human intervention. Such craft will be equipped to independently solve problems as they arise, and fulfill their missions with minimum direction from Earth. 2. Human-Centered Computing Many NASA missions require synergy between humans and computers, with sophisticated computational aids amplifying human cognitive and perceptual abilities. 3. High Performance Computing and Networking Advances in the performance of computing and networking continue to have major impact on a variety of NASA endeavors, ranging from modeling and simulation to analysis of large scientific datasets to collaborative engineering, planning and execution. In addition, RIACS collaborates with NASA scientists to apply IT research to a variety of NASA application domains. RIACS also engages in other activities, such as workshops, seminars, visiting scientist programs and student summer programs, designed to encourage and facilitate collaboration between the university and NASA IT research communities.

  15. Long-term Follow-up Results of a Multi-institutional Phase 2 Study of Concurrent Chemoradiation Therapy for Locally Advanced Cervical Cancer in East and Southeast Asia

    Energy Technology Data Exchange (ETDEWEB)

    Kato, Shingo, E-mail: s_kato@saitama-med.ac.jp [Department of Radiation Oncology, International Medical Center, Saitama Medical University, Saitama (Japan); National Institute of Radiological Sciences of Japan, Chiba (Japan); Ohno, Tatsuya [Gunma University Heavy Ion Medical Center, Gunma University, Gunma (Japan); Thephamongkhol, Kullathorn; Chansilpa, Yaowalak [Division of Radiation Oncology, Department of Radiology, Siriraj Hospital, Faculty of Medicine, Mahidol University, Bangkok (Thailand); Cao, Jianping [School of Radiation Medicine and Public Health, Soochow University, Soochow (China); Xu, Xiaoting [Department of Radiation Oncology, The First Affiliated Hospital of Soochow University, Soochow (China); Devi, C. R. Beena; Swee, Tang Tieng [Department of Radiotherapy and Oncology, Hospital Umum Sarawak, Kuching (Malaysia); Calaguas, Miriam J.C. [Department of Radiation Oncology, St. Luke' s Medical Center, Quezon City, the Philippines (Philippines); Reyes, Rey H. de los [Department of Obstetrics and Gynecology, Dr Jose R. Reyes Memorial Medical Center, Manila, the Philippines (Philippines); Cho, Chul-Koo [Department of Radiation Oncology, Korea Cancer Center Hospital, Seoul (Korea, Republic of); Dung, To Anh [Department of Breast and Gynecology Radiotherapy, National Cancer Institute, Hanoi (Viet Nam); Supriana, Nana [Department of Radiation Therapy, Faculty of Medicine, University of Indonesia, Dr Cipto Mangunkusumo General Hospital, Jakarta (Indonesia); Erawati, Dyah [Division of Radiotherapy, Dr Soetomo General Hospital, Surabaya (Indonesia); Mizuno, Hideyuki [National Institute of Radiological Sciences of Japan, Chiba (Japan); Nakano, Takashi [Department of Radiation Oncology, Gunma University Graduate School of Medicine, Gunma (Japan); Tsujii, Hirohiko [National Institute of Radiological Sciences of Japan, Chiba (Japan)

    2013-09-01

    Purpose: To report the long-term survival and toxicity of a multi-institutional phase 2 study of concurrent chemoradiation therapy (CCRT) for locally advanced cervical cancer in east and southeast Asia. Methods and Materials: Ten institutions from 8 Asian countries participated in the study. Between April 2003 and March 2006, 120 patients (60 with bulky stage IIB and 60 with stage IIIB) were treated with CCRT. Radiation therapy consisted of pelvic external beam radiation therapy and either high-dose-rate or low-dose-rate intracavitary brachytherapy. Five cycles of weekly cisplatin (40 mg/m{sup 2}) were administered during the course of radiation therapy. Treatment results were evaluated by the rates of local control, overall survival, and late toxicities. Results: Median follow-up was 63.7 months, and the follow-up rate at 5 years was 98%. The 5-year local control and overall survival rates for all patients were 76.8% and 55.1%, respectively. The 5-year rates of major late toxicities of the rectum and bladder were 7.9% and 0%, respectively. Conclusions: The long-term results have suggested that CCRT is safe and effective for patients with locally advanced cervical cancer in east and southeast Asia. However, further efforts are needed to improve overall survival.

  16. Molecular Imaging : Computer Reconstruction and Practice - Proceedings of the NATO Advanced Study Institute on Molecular Imaging from Physical Principles to Computer Reconstruction and Practice

    CERN Document Server

    Lemoigne, Yves

    2008-01-01

    This volume collects the lectures presented at the ninth ESI School held at Archamps (FR) in November 2006 and is dedicated to nuclear physics applications in molecular imaging. The lectures focus on the multiple facets of image reconstruction processing and management and illustrate the role of digital imaging in clinical practice. Medical computing and image reconstruction are introduced by analysing the underlying physics principles and their implementation, relevant quality aspects, clinical performance and recent advancements in the field. Several stages of the imaging process are specifically addressed, e.g. optimisation of data acquisition and storage, distributed computing, physiology and detector modelling, computer algorithms for image reconstruction and measurement in tomography applications, for both clinical and biomedical research applications. All topics are presented with didactical language and style, making this book an appropriate reference for students and professionals seeking a comprehen...

  17. ADVANCED CUTTINGS TRANSPORT STUDY

    Energy Technology Data Exchange (ETDEWEB)

    Ergun Kuru; Stefan Miska; Nicholas Takach; Kaveh Ashenayi; Gerald Kane; Len Volk; Mark Pickell; Evren Ozbayoglu; Barkim Demirdal; Paco Vieira; Affonso Lourenco

    1999-10-15

    This report includes a review of the progress made in ACTF Flow Loop development and research during 90 days pre-award period (May 15-July 14, 1999) and the following three months after the project approval date (July15-October 15, 1999) The report presents information on the following specific subjects; (a) Progress in Advanced Cuttings Transport Facility design and development, (b) Progress report on the research project ''Study of Flow of Synthetic Drilling Fluids Under Elevated Pressure and Temperature Conditions'', (c) Progress report on the research project ''Study of Cuttings Transport with Foam Under LPAT Conditions (Joint Project with TUDRP)'', (d) Progress report on the research project ''Study of Cuttings Transport with Aerated Muds Under LPAT Conditions (Joint Project with TUDRP)'', (e) Progress report on the research project ''Study of Foam Flow Behavior Under EPET Conditions'', (f) Progress report on the instrumentation tasks (Tasks 11 and 12) (g) Activities towards technology transfer and developing contacts with oil and service company members.

  18. Advanced commercial tokamak study

    International Nuclear Information System (INIS)

    Thomson, S.L.; Dabiri, A.E.; Keeton, D.C.; Brown, T.G.; Bussell, G.T.

    1985-12-01

    Advanced commercial tokamak studies were performed by the Fusion Engineering Design Center (FEDC) as a participant in the Tokamak Power Systems Studies (TPSS) project coordinated by the Office of Fusion Energy. The FEDC studies addressed the issues of tokamak reactor cost, size, and complexity. A scoping study model was developed to determine the effect of beta on tokamak economics, and it was found that a competitive cost of electricity could be achieved at a beta of 10 to 15%. The implications of operating at a beta of up to 25% were also addressed. It was found that the economics of fusion, like those of fission, improve as unit size increases. However, small units were found to be competitive as elements of a multiplex plant, provided that unit cost and maintenance time reductions are realized for the small units. The modular tokamak configuration combined several new approaches to develop a less complex and lower cost reactor. The modular design combines the toroidal field coil with the reactor structure, locates the primary vacuum boundary at the reactor cell wall, and uses a vertical assembly and maintenance approach. 12 refs., 19 figs

  19. Imitation Modeling and Institutional Studies

    Directory of Open Access Journals (Sweden)

    Maksim Y. Barbashin

    2017-09-01

    Full Text Available This article discusses the use of imitation modeling in the conduct of institutional research. The institutional approach is based on the observation of social behavior. To understand a social process means to determine the key rules that individuals use, undertaking social actions associated with this process or phenomenon. This does not mean that institutions determine behavioral reactions, although there are a number of social situations where the majority of individuals follow the dominant rules. If the main laws of development of the institutional patterns are known, one can describe most of the social processes accurately. The author believes that the main difficulty with the analysis of institutional processes is their recursive nature: from the standards of behavior one may find the proposed actions of social agents who follow, obey or violate institutions, but the possibility of reconstructive analysis is not obvious. The author demonstrates how the institutional approach is applied to the analysis of social behavior. The article describes the basic principles and methodology of imitation modeling. Imitation modeling reveals the importance of institutions in structuring social transactions. The article concludes that in the long term institutional processes are not determined by initial conditions.

  20. ADVANCED CUTTINGS TRANSPORT STUDY

    Energy Technology Data Exchange (ETDEWEB)

    Troy Reed; Stefan Miska; Nicholas Takach; Kaveh Ashenayi; Gerald Kane; Mark Pickell; Len Volk; Mike Volk; Barkim Demirdal; Affonso Lourenco; Evren Ozbayoglu; Paco Vieira; Lei Zhou

    2000-01-30

    This is the second quarterly progress report for Year 2 of the ACTS project. It includes a review of progress made in Flow Loop development and research during the period of time between Oct 1, 2000 and December 31, 2000. This report presents a review of progress on the following specific tasks: (a) Design and development of an Advanced Cuttings Transport Facility (Task 2: Addition of a foam generation and breaker system), (b) Research project (Task 6): ''Study of Cuttings Transport with Foam Under LPAT Conditions (Joint Project with TUDRP)'', (c) Research project (Task 7): ''Study of Cuttings Transport with Aerated Muds Under LPAT Conditions (Joint Project with TUDRP)'', (d) Research project (Task 8): ''Study of Flow of Synthetic Drilling Fluids Under Elevated Pressure and Temperature Conditions'', (e) Research project (Task 9): ''Study of Foam Flow Behavior Under EPET Conditions'', (f) Research project (Task 10): ''Study of Cuttings Transport with Aerated Mud Under Elevated Pressure and Temperature Conditions'', (g) Research on instrumentation tasks to measure: Cuttings concentration and distribution in a flowing slurry (Task 11), and Foam properties while transporting cuttings. (Task 12), (h) Development of a Safety program for the ACTS Flow Loop. Progress on a comprehensive safety review of all flow-loop components and operational procedures. (Task 1S). (i) Activities towards technology transfer and developing contacts with Petroleum and service company members, and increasing the number of JIP members. The tasks Completed During This Quarter are Task 7 and Task 8.

  1. Establishment of an Institute for Fusion Studies

    International Nuclear Information System (INIS)

    Hazeltine, R.D.

    1992-07-01

    The Institute for Fusion Studies is a national center for theoretical fusion plasma physics research. Its purposes are: (1) to conduct research on theoretical questions concerning the achievement of controlled fusion energy by means of magnetic confinement--including both fundamental problems of long-range significance, as well as shorter-term issues; (2) to serve as a center for information exchange, nationally and internationally, by hosting exchange visits, conferences, and workshops; (3) and to train students and postdoctoral research personnel for the fusion energy program and plasma physics research areas. The theoretical research results that are obtained by the Institute contribute mainly to the progress of national and international efforts in nuclear fusion research, whose goal is the development of fusion power.as a basic energy source. In addition to its primary focus on fusion physics, the Institute is also involved with research in related fields, such as advanced computing techniques, nonlinear dynamics, plasma astrophysics, and accelerator physics. The work of EFS scientists continued to receive national and international recognition. Numerous invited papers were given during the past year at workshops, conferences, and scientific meetings. Last year IFS scientists published 95 scientific articles in technical journals and monographs

  2. Advancing institutional anomie theory: a microlevel examination connecting culture, institutions, and deviance.

    Science.gov (United States)

    Muftić, Lisa R

    2006-12-01

    Institutional anomie theory (IAT) contends that crime can be explained by an examination of American society, particularly the exaggerated emphasis on economic success inherent in American culture, which has created a "cheating orientation" that permeates structural institutions, including academia. Consistent with its macrosocial perspective, previous tests of IAT have examined IAT variables at the structural level only. The current study tests the robustness of IAT by operationalizing IAT variables at the individual level and looking at a minor form of deviance, student cheating. The author also examines the role statistical modeling has in testing the theory at the microlevel. Undergraduates, 122 American born and 48 international, were surveyed about their cheating behaviors and adherence to economic goal orientations. Results related to the hypothesis that American students, relative to foreign-born students, will have an increased adherence to economic goal orientations that increase cheating behaviors are presented, as are suggestions for future studies.

  3. How institutional change and individual researchers helped advance clinical guidelines in American health care.

    Science.gov (United States)

    Nigam, Amit

    2013-06-01

    Clinical guidelines are important tools for managing health care quality. Research on the origins of guidelines primarily focuses on the institutional causes of their emergence and growth. Individual medical researchers, however, have played important roles. This paper develops knowledge of the role of individual medical researchers in advancing guidelines, and of how researchers' efforts were enabled or constrained by broader institutional changes. Drawing on an analytical case study focused on the role of Kerr White, John Wennberg, and Robert Brook, it shows that guidelines were a product of the interplay between institutional change in the medical field and actions by individual researchers, acting as institutional entrepreneurs. Increased government involvement in the health care field triggered the involvement of a range of new actors in health care. These new organizations created a context that allowed individual researchers to advance guidelines by creating job opportunities, providing research funding, and creating opportunities for researchers to engage with the policy process. Individual researchers availed of this context to both advance their ideas, and to draw new actors into the field. Copyright © 2013. Published by Elsevier Ltd.

  4. Praxeologies and Institutional Interactions in the Advanced Science Teacher Education

    DEFF Research Database (Denmark)

    Rasmussen, Klaus

    disciplines in conjunction. In particular the inquiry process of Study and Research Paths (SRP) is experimented as a promising design to bring about disciplinary interaction. SRP is internationally a very recent design, entirely new to Danish teacher education, and the thesis add to the knowledge of its......The present thesis consists of six papers that address three important aspects in mathematics and science teacher education: ‘Integrating two or more teaching disciplines’, ‘learning from practice’ and ‘interaction between institutions’. These aspects are studied in combination as they have...... unfolded in the context of developing and implementing a Danish education programme called the Advanced Science Teacher Education (ASTE), that aim to educate lower secondary school teachers, who among other things are to excel at interdisciplinarity. The essence of integrated teaching is elusive...

  5. ADVANCED CUTTINGS TRANSPORT STUDY

    Energy Technology Data Exchange (ETDEWEB)

    Stefan Miska; Troy Reed; Ergun Kuru

    2004-09-30

    The Advanced Cuttings Transport Study (ACTS) was a 5-year JIP project undertaken at the University of Tulsa (TU). The project was sponsored by the U.S. Department of Energy (DOE) and JIP member companies. The objectives of the project were: (1) to develop and construct a new research facility that would allow three-phase (gas, liquid and cuttings) flow experiments under ambient and EPET (elevated pressure and temperature) conditions, and at different angle of inclinations and drill pipe rotation speeds; (2) to conduct experiments and develop a data base for the industry and academia; and (3) to develop mechanistic models for optimization of drilling hydraulics and cuttings transport. This project consisted of research studies, flow loop construction and instrumentation development. Following a one-year period for basic flow loop construction, a proposal was submitted by TU to the DOE for a five-year project that was organized in such a manner as to provide a logical progression of research experiments as well as additions to the basic flow loop. The flow loop additions and improvements included: (1) elevated temperature capability; (2) two-phase (gas and liquid, foam etc.) capability; (3) cuttings injection and removal system; (4) drill pipe rotation system; and (5) drilling section elevation system. In parallel with the flow loop construction, hydraulics and cuttings transport studies were preformed using drilling foams and aerated muds. In addition, hydraulics and rheology of synthetic drilling fluids were investigated. The studies were performed under ambient and EPET conditions. The effects of temperature and pressure on the hydraulics and cuttings transport were investigated. Mechanistic models were developed to predict frictional pressure loss and cuttings transport in horizontal and near-horizontal configurations. Model predictions were compared with the measured data. Predominantly, model predictions show satisfactory agreements with the measured data. As a

  6. HKUST Jockey Club Institute for Advanced Study

    CERN Document Server

    2015-01-01

    After the discovery of the Higgs boson, the main objectives of the future high-energy physics are the precise measurement of Higgs properties and searches for new physics. These objectives strongly motivate the construction of an e+e- Higgs factory and a new pp collider with energy significantly higher than the LHC. The Higgs boson plays a crucial role in explaining spontaneous electroweak symmetry breaking and the mass generation of the known fundamental particles. It is thus important to measure precisely the Higgs-gauge couplings, the Higgs-Yukawa couplings and the Higgs self-couplings. A future Higgs factory would achieve such a goal significantly better than the LHC does. Such precision measurements can also unveil new physics that alter the Higgs properties. There are good reasons to expect that new physics should emerge at the TeV scale or above. A higher energy pp collider will be crucial for exploring new physics and the spectroscopy of any to-be-discovered particle at the LHC which may not be able...

  7. Latina Social Studies Teachers Negotiating Public Institutions

    Science.gov (United States)

    Rivas, Elizabeth D.

    2017-01-01

    This mixed methods study explores the institutionalized master narrative of public institutions and how the mandated policies enacted by public institutions impact Latina social studies teachers when delivering instruction to their students. A socio-transformative constructivist framework guides this study to affirm that knowledge is socially…

  8. Perspectives on Performance Indicators: GCE Advanced Level and Differences Between Institution Types in Cost Effectiveness.

    Science.gov (United States)

    Fielding, A.

    1998-01-01

    Applies multilevel models of cost-effectiveness to numerous types of (British) institutions providing courses of instruction in the General Certificate of Education at Advanced Level. Different impressions may be gained about an institution's relative effectiveness when cost considerations are combined with outcome measures. Data evaluation needs…

  9. A Survey of AASCU Institutions: Compliance with Selected NCATE Standards at the Advanced Level.

    Science.gov (United States)

    Sparapani, Ervin; Nelson, David

    This report presents the results of a survey of advanced programs in teacher education at member institutions of the American Association of State Colleges and Universities (AASCU). It is the opinion of researchers that several of the NCATE criteria apply more appropriately to basic programs than to advanced, especially in the categories related…

  10. Quality Assurance Issues in Conducting Multi-Institutional Advanced Technology Clinical Trials

    International Nuclear Information System (INIS)

    Purdy, James A.

    2008-01-01

    The National Cancer Institute-sponsored Advanced Technology Quality Assurance (QA) Consortium, which consisted of the Image-Guided Therapy QA Center, Radiation Therapy Oncology Group, Radiological Physics Center, Quality Assurance Review Center, and Resource Center for Emerging Technologies, has pioneered the development of an infrastructure and QA method for advanced technology clinical trials that requires volumetric digital data submission of a protocol patient's treatment plan and verification data. In particular, the Image-Guided Therapy QA Center has nearly 15 years experience in facilitating QA review for Radiation Therapy Oncology Group advanced technology clinical trials. This QA process includes (1) a data integrity review for completeness of protocol required elements, the format of data, and possible data corruption, and recalculation of dose-volume histograms; (2) a review of compliance with target volume and organ-at-risk contours by study chairs; and (3) a review of dose prescription and dose heterogeneity compliance by the Radiation Therapy Oncology Group Headquarters Dosimetry Group or the Radiological Physics Center dosimetrists (for brachytherapy protocols). This report reviews the lessons learned and the QA challenges presented by the use of advanced treatment modalities in clinical trials requiring volumetric digital data submission

  11. Project for the Institution of an Advanced Course in Physics

    Science.gov (United States)

    Teodorani, M.; Nobili, G.

    2006-06-01

    A project for an advanced course in physics at the master level, is presented in great detail. The goal of this project is to create a specific and rigorous training for those who want to carry out experimental and theoretical research on "anomalies" in physical science, especially from the point of view of atmospheric physics, plasma physics, photonic physics, biophysics, astronomy and astrophysics. A specific training in powering mental skills is planned as well. The planned teaching program is presented as a two-year course where the following subjects are intended to be taught: cognitive techniques (I and II), radiation physics (I and II), biophysics (I and II), bioastronomy (I and II), history of physics (I and II), didactics of physics, physics of atmospheric plasmas, physics of non-stationary photonic events, physics of non-linear processes, complements of quantum mechanics, quantum informatics, research methodology in physics and astronomy, computer science methods in physics and astronomy, optoelectronics, radioelectronics. Detailed teaching programs, didactics methods, and performance evaluation, are presented for each subject. The technical content of this project is preceded by an ample introduction that shows all the reasons of this kind of physics course, particularly aimed at innovation in physical science.

  12. Local Institutional Development and Organizational Change for Advancing Sustainable Urban Water Futures

    Science.gov (United States)

    Brown, Rebekah R.

    2008-02-01

    This paper presents the local institutional and organizational development insights from a five-year ongoing interdisciplinary research project focused on advancing the implementation of sustainable urban water management. While it is broadly acknowledged that the inertia associated with administrative systems is possibly the most significant obstacle to advancing sustainable urban water management, contemporary research still largely prioritizes investigations at the technological level. This research is explicitly concerned with critically informing the design of methodologies for mobilizing and overcoming the administrative inertia of traditional urban water management practice. The results of fourteen in-depth case studies of local government organizations across Metropolitan Sydney primarily reveal that (i) the political institutionalization of environmental concern and (ii) the commitment to local leadership and organizational learning are key corporate attributes for enabling sustainable management. A typology of five organizational development phases has been proposed as both a heuristic and capacity benchmarking tool for urban water strategists, policy makers, and decision makers that are focused on improving the level of local implementation of sustainable urban water management activity. While this investigation has focused on local government, these findings do provide guideposts for assessing the development needs of future capacity building programs across a range of different institutional contexts.

  13. Fifteen years' review of advanced childhood neuroblastoma from a single institution in Hong Kong.

    Science.gov (United States)

    Leung, C K

    1998-05-01

    To assess the progress in the treatment of advanced childhood neuroblastoma. From 1981 to 1996, there were 32 children with neuroblastoma (NB) diagnosed, staged and treated in our institution. There were 4 patients with stage II NB (12%), 5 stage III (16%), 21 stage IV (66%) and 2 stage IV s (6%). The NBs were excised if CT scan indicated that the tumors were operable. For advanced NB, stages III and IV, multiple drug chemotherapy was started first and operability was assessed with serial CT scan examinations. Once the X-ray imaging indicated the tumors were operable, surgical interventions were done. The medical records of the advanced NB were reviewed. In the initial period of the study, 9 patients were treated using the VAC protocol [vincristine (vcr), adriamycin (adria) and cyclophosphamide (cyc)]. No patient was convertible to operable and all died with a mean survival of 10 months. OPEC [vcr, cyc, VM26, cisplatin (cis)], Rapid COJEC (carboplatin, VP16, vcr, cis and cyc) and more recently N6 protocol (cyc, adria, vcr, VP16, cis) was used for 17 patients. 80% of them were converted to operable. In 4 patients, surgical specimens showed only necrotic tissue without viable tumor tissue and 6 (35%) tumors were converted to ganglioneuroma or ganglioneuroblastoma. Although 2 (12%) patients died of fungal septicemia and 1 (6%) developed Fanconi's syndrome after chemotherapy, the mean survival period increased to 27 months. In the 10 survivors (60%), 4 had megatherapy with melphalan followed by autologous peripheral blood stem cell (PBSC) transplantation and 2 were waiting for transplantation. There is a high percentage of advanced NB on presentation in Hong Kong. With more potent multiple drug chemotherapy for advanced stage NB there are (1) improvement in the survival of these patients, (2) opportunities for more operations for tumor excision and (3) opportunities for autologous PBSC transplantation for better tumor eradication.

  14. MARS: Mirror Advanced Reactor Study

    International Nuclear Information System (INIS)

    Logan, B.G.

    1984-01-01

    A recently completed two-year study of a commercial tandem mirror reactor design [Mirror Advanced Reactor Study (MARS)] is briefly reviewed. The end plugs are designed for trapped particle stability, MHD ballooning, balanced geodesic curvature, and small radial electric fields in the central cell. New technologies such as lithium-lead blankets, 24T hybrid coils, gridless direct converters and plasma halo vacuum pumps are highlighted

  15. Center for Advanced Energy Studies Program Plan

    Energy Technology Data Exchange (ETDEWEB)

    Kevin Kostelnik

    2005-09-01

    The world is facing critical energy-related challenges regarding world and national energy demands, advanced science and energy technology delivery, nuclear engineering educational shortfalls, and adequately trained technical staff. Resolution of these issues is important for the United States to ensure a secure and affordable energy supply, which is essential for maintaining U.S. national security, continued economic prosperity, and future sustainable development. One way that the U.S. Department of Energy (DOE) is addressing these challenges is by tasking the Battelle Energy Alliance, LLC (BEA) with developing the Center for Advanced Energy Studies (CAES) at the Idaho National Laboratory (INL). By 2015, CAES will be a self-sustaining, world-class, academic and research institution where the INL; DOE; Idaho, regional, and other national universities; and the international community will cooperate to conduct critical energy-related research, classroom instruction, technical training, policy conceptualization, public dialogue, and other events.

  16. First 3 years of operation of RIACS (Research Institute for Advanced Computer Science) (1983-1985)

    Science.gov (United States)

    Denning, P. J.

    1986-01-01

    The focus of the Research Institute for Advanced Computer Science (RIACS) is to explore matches between advanced computing architectures and the processes of scientific research. An architecture evaluation of the MIT static dataflow machine, specification of a graphical language for expressing distributed computations, and specification of an expert system for aiding in grid generation for two-dimensional flow problems was initiated. Research projects for 1984 and 1985 are summarized.

  17. Mirror Advanced Reactor Study (MARS)

    International Nuclear Information System (INIS)

    Logan, B.G.

    1983-01-01

    Progress in a two year study of a 1200 MWe commercial tandem mirror reactor (MARS - Mirror Advanced Reactor Study) has reached the point where major reactor system technologies are identified. New design features of the magnets, blankets, plug heating systems and direct converter are described. With the innovation of radial drift pumping to maintain low plug density, reactor recirculating power fraction is reduced to 20%. Dominance of radial ion and impurity losses into the halo permits gridless, circular direct converters to be dramatically reduced in size. Comparisons of MARS with the Starfire tokamak design are made

  18. Advanced nuclear systems. Review study

    International Nuclear Information System (INIS)

    Liebert, Wolfgang; Glaser, Alexander; Pistner, Christoph; Baehr, Roland; Hahn, Lothar

    1999-04-01

    The task of this review study is to from provide an overview of the developments in the field of the various advanced nuclear systems, and to create the basis for more comprehensive studies of technology assessment. In an overview the concepts for advanced nuclear systems pursued worldwide are subdivided into eight subgroups. A coarse examination raster (set pattern) is developed to enable a detailed examination of the selected systems. In addition to a focus on enhanced safety features, further aspects are also taken into consideration, like the lowering of the proliferation risk, the enhancement of the economic competitiveness of the facilities and new usage possibilities (for instance concerning the relaxation of the waste disposal problem or the usage of alternative fuels to uranium). The question about the expected time span for realization and the discussion about the obstacles on the way to a commercially usable reactor also play a substantial role as well as disposal requirements as far as they can be presently recognized. In the central chapter of this study, the documentation of the representatively selected concepts is evaluated as well as existing technology assessment studies and expert opinions. In a few cases where this appears to be necessary, according technical literature, further policy advisory reports, expert statements as well as other relevant sources are taken into account. Contradictions, different assessments and dissents in the literature as well as a few unsettled questions are thus indicated. The potential of advanced nuclear systems with respect to economical and societal as well as environmental objectives cannot exclusively be measured by the corresponding intrinsic or in comparison remarkable technical improvements. The acceptability of novel or improved systems in nuclear technology will have to be judged by their convincing solutions for the crucial questions of safety, nuclear waste and risk of proliferation of nuclear weapons

  19. Institutional Advancement: A Marketing Perspective. Part II: A Status Report, 1978-79.

    Science.gov (United States)

    Moriarty, Daniel F.

    This follow-up report examines the status of the recruitment and retention strategies implemented by Triton College in 1978 as part of an effort to utilize the marketing concept in identifying and meeting changing educational needs. The report first provides operational definitions for "institutional advancement,""marketing concept,""promotion,"…

  20. NATO Advanced Research Institute on the Application of Systems Science to Energy Policy Planning

    CERN Document Server

    Cherniavsky, E; Laughton, M; Ruff, L

    1981-01-01

    The Advanced Research Institute (ARI) on "The Application of Systems Science to Energy Policy Planning" was held under the auspices of the NATO Special Programme Panel on Systems Science in collaboration with the National Center for Analysis of Energy Sys­ tems, Brookhaven National Laboratory, USA, as a part of the NATO Science Committee's continuous effort to promote the advancement of science through international cooperation. Advanced Research Institutes are sponsored by the NATO Science Committee for the purposes of bringing together senior scientists to seek consensus on an assessment of the present state of knowl­ edge on a specific topic and to make recommendations for future research directions. Meetings are structured to encourage inten­ sive group discussion. Invitees are carefully selected so that the group as a whole will contain the experience and expertise neces­ sary to make the conclusions valid and significant. A final report is published presenting the various viewpoints and conclusions....

  1. Advanced Neutron Source enrichment study

    International Nuclear Information System (INIS)

    Bari, R.A.; Ludewig, H.; Weeks, J.R.

    1996-01-01

    A study has been performed of the impact on performance of using low-enriched uranium (20% 235 U) or medium-enriched uranium (35% 235 U) as an alternative fuel for the Advanced Neutron Source, which was initially designed to use uranium enriched to 93% 235 U. Higher fuel densities and larger volume cores were evaluated at the lower enrichments in terms of impact on neutron flux, safety, safeguards, technical feasibility, and cost. The feasibility of fabricating uranium silicide fuel at increasing material density was specifically addressed by a panel of international experts on research reactor fuels. The most viable alternative designs for the reactor at lower enrichments were identified and discussed. Several sensitivity analyses were performed to gain an understanding of the performance of the reactor at parametric values of power, fuel density, core volume, and enrichment that were interpolations between the boundary values imposed on the study or extrapolations from known technology

  2. Advances in outcomes measurement in rehabilitation medicine: current initiatives from the National Institutes of Health and the National Institute on Disability and Rehabilitation Research.

    Science.gov (United States)

    Tulsky, David S; Carlozzi, Noelle E; Cella, David

    2011-10-01

    The articles in this supplement present recent advances in the measurement of patient-reported health-related quality-of-life (HRQOL) outcomes. Specifically, these articles highlight the combined efforts of the National Institutes of Health, National Institute for Neurological Disorders and Stroke, National Center on Medical Rehabilitation Research, National Institute on Disability and Rehabilitation Research, and Department of Veterans Affairs Rehabilitation Research and Development Service to improve HRQOL measurement. In addition, this supplement is intended to provide rehabilitation professionals with information about these efforts and the implications that these advances in outcomes measurement have for rehabilitation medicine and clinical practice. These new measurement scales use state-of-the-art method techniques, including item response theory and computerized adaptive testing. In addition, scale development involves both qualitative and quantitative methods, as well as the administration of items to hundreds or even thousands of research participants. The scales deliberately have been built with overlap of items between scales so that linkages and equivalency scores can be computed. Ultimately, these scales should facilitate direct comparison of outcomes instruments across studies and will serve as standard data elements across research trials without compromising the specificity of disease- or condition-targeted measures. This supplement includes the initial publications for many of these new measurement initiatives, each of which provides researchers and clinicians with better tools for evaluation of the efficacy of their interventions. Copyright © 2011 American Congress of Rehabilitation Medicine. Published by Elsevier Inc. All rights reserved.

  3. Studying at the UCL Institute of Archaeology

    Directory of Open Access Journals (Sweden)

    Bill Sillar

    2013-10-01

    Full Text Available Ranked 1st in 'The Guardian' (2013 league table for studying archaeology Ranked 2nd in 'The Times' (2013 ‘Good University Guide’ 100% of Institute undergraduate finalists expressed satisfaction with our teaching and support in the UK National Student Surveys 2010 and 2011 Students at the UCL Institute of Archaeology discover the rich diversity of the human past, exploring societies from two million years ago to the present day, and asking questions of relevance to our shared global future. To address these questions students integrate the humanities and the sciences; using a wide range of approaches to collect, evaluate and interpret relevant evidence. At UCL and during survey and excavation projects students make life-long friends while developing teamwork, management and leadership skills. Studying archaeology demands energy and enthusiasm, it challenges expectations while developing the problem-solving and transferable skills which all employers are looking for. Graduates from the Institute go on to make wide-ranging contributions to society, including business, academia and archaeology.

  4. Multi-institutional phase I study of low-dose ultra-fractionated radiotherapy as a chemosensitizer for gemcitabine and erlotinib in patients with locally advanced or limited metastatic pancreatic cancer

    International Nuclear Information System (INIS)

    Konski, Andre; Meyer, Joshua E.; Joiner, Michael; Hall, Michael J.; Philip, Philip; Shields, Anthony; McSpadden, Erin; Choi, Minsig; Adaire, Beth; Duncan, Gail; Meropol, Neal J.; Cescon, Terrence P.; Cohen, Steven J.

    2014-01-01

    Purpose: Gemcitabine (G) has been shown to sensitize pancreatic cancer to radiotherapy but requires lower doses of G and thus delays aggressive systemic treatment, potentially leading to distant failure. We initiated a phase I trial combining ultra-fractionated low-dose radiotherapy with full dose G and erlotinib in the treatment of patients with advanced pancreatic cancer. Methods: Patients with locally advanced or metastatic pancreatic cancer confined to the abdomen and an ECOG performance status (PS) of 0–1 who had received 0–1 prior regimens (without G or E) and no prior radiotherapy were eligible. Patients were treated in 21 day cycles with G IV days 1 and 8, E once PO QD, and twice daily RT fractions separated by at least 4 h on days 1, 2, 8, and 9. Whole abdominal RT fields were used. Primary endpoint was to define dose limiting toxicity (DLT) and the maximum tolerated dose (MTD). Results: 27 patients (median age 64 years and 15 male) were enrolled between 11/24/08 and 4/12/12. 1 patient withdrew consent prior to receiving any protocol therapy. 17 patients had a PS of 1. The majority of patients were stage IV. One DLT was noted out of 7 patients at dose level (DL) 1. Subsequently no DLTs were noted in 3 patients each enrolled at DL2-4 or 11 patients in the expansion cohort. The majority of grade 3 toxicities were hematologic with 1 grade 5 bowel perforation in dose level 1 in cycle 4. Best response in 24 evaluable patients: PR (8), stable (15), PD 1. Median survival for the entire group was 9.1 months. Conclusion: This phase I study combining low-dose ultra-fractionated RT as a sensitizer to full dose G plus E was well tolerated with encouraging efficacy. This represents a novel strategy worthy of further investigation in advanced pancreatic cancer patients

  5. 2001 Industry Studies: Advanced Manufacturing

    Science.gov (United States)

    2001-05-28

    oriented, 19 and manufacturers are employing the Internet and associated information technologies to better integrate supply chains and form extended...ways to compete in world markets . As part of this ongoing transformation, the broad implementation of advanced manufacturing technologies , processes...competitive advantages and better performance in world markets . Importantly, advanced manufacturing involves the innovative integration of new technology

  6. [Establishing and hosting an Institute for Fusion Studies

    International Nuclear Information System (INIS)

    Baldwin, D.E.

    1989-07-01

    Significant progress was made during the past year in carrying out theoretical investigations pursuant to the scientific mission of the Institute. These achievements may be approximately classified in terms of the following categories (often with considerable overlap): sawteeth and MHD studies, turbulence theory and plasma transport, computational plasma physics, stability theory, mathematical physics, advanced ideas, and space plasma physics-related problems. An overview of this work is contained in this report. Detailed summaries of IFS Reports written during FY 89 are given in abstract form

  7. Long-Term Follow-Up of Preoperative Pelvic Radiation Therapy and Concomitant Boost Irradiation in Locally Advanced Rectal Cancer Patients: A Multi-Institutional Phase II Study (KROG 04-01)

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Jong Hoon [Department of Radiation Oncology, Seoul St. Mary' s Hospital, College of Medicine, Catholic University of Korea, Seoul (Korea, Republic of); Department of Radiation Oncology, St. Vincent' s Hospital, Catholic University of Korea, Suwon (Korea, Republic of); Kim, Dae Yong [Center for Colorectal Cancer, Research Institute and Hospital, National Cancer Center, Go-Yang (Korea, Republic of); Nam, Taek-Keun [Department of Radiation Oncology, Chonnam National University Hospital, Hwa-Sun (Korea, Republic of); Yoon, Sei-Chul [Department of Radiation Oncology, Seoul St. Mary' s Hospital, College of Medicine, Catholic University of Korea, Seoul (Korea, Republic of); Lee, Doo Seok [Department of Colorectal Surgery, Daehang Hospital, Seoul (Korea, Republic of); Park, Ji Won; Oh, Jae Hwan; Chang, Hee Jin [Center for Colorectal Cancer, Research Institute and Hospital, National Cancer Center, Go-Yang (Korea, Republic of); Yoon, Mee Sun; Jeong, Jae-Uk [Department of Radiation Oncology, Chonnam National University Hospital, Hwa-Sun (Korea, Republic of); Jang, Hong Seok, E-mail: hsjang11@catholic.ac.kr [Department of Radiation Oncology, Seoul St. Mary' s Hospital, College of Medicine, Catholic University of Korea, Seoul (Korea, Republic of)

    2012-11-15

    Purpose: To perform a prospective phase II study to investigate the efficacy and safety of preoperative pelvic radiation therapy and concomitant small-field boost irradiation with 5-fluorouracil and leucovorin for 5 weeks in locally advanced rectal cancer patients. Methods and Materials: Sixty-nine patients with locally advanced, nonmetastatic, mid-to-lower rectal cancer were prospectively enrolled. They had received preoperative chemoradiation therapy and total mesorectal excision. Pelvic radiation therapy of 43.2 Gy in 24 fractions plus concomitant boost radiation therapy of 7.2 Gy in 12 fractions was delivered to the pelvis and tumor bed for 5 weeks. Two cycles of 5-fluorouracil and leucovorin were administered for 3 days in the first and fifth week of radiation therapy. The pathologic response, survival outcome, and treatment toxicity were evaluated for the study endpoints. Results: Of 69 patients, 8 (11.6%) had a pathologically complete response. Downstaging rates were 40.5% for T classification and 68.1% for N classification. At the median follow-up of 69 months, 36 patients have been followed up for more than 5 years. The 5-year disease-free survival (DFS) and overall survival rates were 66.0% and 75.3%, respectively. Higher pathologic T (P = .045) and N (P = .032) classification were significant adverse prognostic factors for DFS, and high-grade histology was an adverse prognostic factor for both DFS (P = .025) and overall survival (P = .031) on the multivariate analysis. Fifteen patients (21.7%) experienced grade 3 or 4 acute toxicity, and 7 patients (10.1%) had long-term toxicity. Conclusion: Preoperative pelvic radiation therapy with concomitant boost irradiation with 5-fluorouracil and leucovorin for 5 weeks showed acceptable acute and long-term toxicities. However, the benefit of concomitant small-field boost irradiation for 5 weeks in rectal cancer patients was not demonstrated beyond conventional irradiation for 6 weeks in terms of tumor response and

  8. Advanced Chemical Propulsion System Study

    Science.gov (United States)

    Portz, Ron; Alexander, Leslie; Chapman, Jack; England, Chris; Henderson, Scott; Krismer, David; Lu, Frank; Wilson, Kim; Miller, Scott

    2007-01-01

    A detailed; mission-level systems study has been performed to show the benefit resulting from engine performance gains that will result from NASA's In-Space Propulsion ROSS Cycle 3A NRA, Advanced Chemical Technology sub-topic. The technology development roadmap to accomplish the NRA goals are also detailed in this paper. NASA-Marshall and NASA-JPL have conducted mission-level studies to define engine requirements, operating conditions, and interfaces. Five reference missions have been chosen for this analysis based on scientific interest, current launch vehicle capability and trends in space craft size: a) GTO to GEO, 4800 kg, delta-V for GEO insertion only approx.1830 m/s; b) Titan Orbiter with aerocapture, 6620 kg, total delta V approx.210 m/s, mostly for periapsis raise after aerocapture; c) Enceladus Orbiter (Titan aerocapture) 6620 kg, delta V approx.2400 m/s; d) Europa Orbiter, 2170 kg, total delta V approx.2600 m/s; and e) Mars Orbiter, 2250 kg, total delta V approx.1860 m/s. The figures of merit used to define the benefit of increased propulsion efficiency at the spacecraft level include propulsion subsystem wet mass, volume and overall cost. The objective of the NRA is to increase the specific impulse of pressure-fed earth storable bipropellant rocket engines to greater than 330 seconds with nitrogen tetroxide and monomothylhydrazine propellants and greater than 335 , seconds with nitrogen tetroxide and hydrazine. Achievement of the NRA goals will significantly benefit NASA interplanetary missions and other government and commercial opportunities by enabling reduced launch weight and/or increased payload. The study also constitutes a crucial stepping stone to future development, such as pump-fed storable engines.

  9. The Use of Central Pathology Review With Digital Slide Scanning in Advanced-stage Mycosis Fungoides and Sézary Syndrome: A Multi-institutional and International Pathology Study.

    Science.gov (United States)

    Gru, Alejandro A; Kim, Jinah; Pulitzer, Melissa; Guitart, Joan; Battistella, Maxime; Wood, Gary S; Cerroni, Lorenzo; Kempf, Werner; Willemze, Rein; Pawade, Joya; Querfeld, Christiane; Schaffer, Andras; Pincus, Laura; Tetzlaff, Michael; Duvic, Madeleine; Scarisbrick, Julia; Porcu, Pierluigi; Mangold, Aaron R; DiCaudo, David J; Shinohara, Michi; Hong, Eric K; Horton, Bethany; Kim, Youn H

    2018-06-01

    This pathology PILOT study aims to define the role and feasibility of centralized pathology review in a cohort of 75 patients from different centers in the United States and Europe using digital slide scanning. The pathologic material from 75 patients who had been diagnosed with mycosis fungoides/Sézary syndrome and were clinically staged as IIb or above was retrieved from 11 participating centers. Each pathology reviewer was provided with the pathologic diagnosis (by the referring pathologist), and the following list of histopathologic criteria (presence or absence) from the initial report: epidermotropism, folliculotropism (FT), large cell transformation, syringotropism, and granulomas. Patients with advance stage were selected for this study as this is a population where there is significant variability in the diagnosis of pathologic prognostic and predictive biomarkers. The slides were digitally scanned with an Aperio scanner and consensus review of cases occurred when major or minor discrepancies between the referral diagnosis and central pathology review occurred. Among the 75 cases, 70 (93.3%) had a final consensus diagnosis between the 3 central review pathologists. The overall agreement between the consensus review and the referring pathologist was 60%. The overall agreement was also higher between the reviewers and consensus review, compared with the referring pathologist and consensus. 65.3% of cases had some type of discrepancy (major or minor) between the outside and consensus review. Major discrepancies were seen in 34 of 73 cases (46.6%; 73 cases indicated a yes or no response). Minor discrepancies were seen in 32 of 75 (42.7%) of cases. Most of the major discrepancies were accounted by a difference in interpretation in the presence or absence of large cell transformation or FT. Most minor discrepancies were explained by a different interpretation in the expression of CD30. We found digital slide scanning to be a beneficial, reliable, and practical

  10. STRATEGIES FOR ADVANCE IN DEVELOPMENT OF A HEALTH CARE INSTITUTION FOR SPECIALIZED PRE-HOSPITAL MEDICAL AID

    Directory of Open Access Journals (Sweden)

    Desislava Todorova

    2017-12-01

    Full Text Available which brings about a competitive environment for an increase of the quality of services offered. The aim of the study is making evident the recommendatory strategies of a health care institution for specialized pre-hospital medical aid in Sofia City for activity performed in the period from the year 2016 to 2018. The task assigned is an analysis of the opportunities for the widening of the activity, products, and markets of "DCC XXIVth-Sofia" EOOD. The chosen healthcare institution is active in a competitive environment in Sofia City, and in the district that it serves. Data from the health care institution, data from the institutions of National Statistics, and scientific literature on the topic were used in connection with the analysis. Some essential approaches of management were applied - analysis of the market share, and SWOT analysis, for determination of strategy. The conclusions of the analysis performed showed four possible strategies of advance in development and opportunities for activity in each of them. The administration of "DCC XXIVth-Sofia" EOOD had opportunities to all practical purposes for minimization of the negative effects, induced by the weaknesses and threats, and to successfully develop the activity - during the period from the year 2016 to 2018. Both the activity of the healthcare institution and the public health services of the population in the corresponding village/town/city depend on the choice of the administration and on its execution by the personnel.

  11. Re-challenge with pemetrexed in advanced mesothelioma: a multi-institutional experience

    Directory of Open Access Journals (Sweden)

    Bearz Alessandra

    2012-09-01

    Full Text Available Abstract Background Although first-line therapy for patients affected by advanced mesothelioma is well established, there is a lack of data regarding the impact of second-line treatment. Methods We retrospectively collected data of patients affected by advanced mesothelioma, already treated with first-line therapy based on pemetrexed and platin, with a response (partial response or stable disease lasting at least 6 months, and re-treated with a pemetrexed-based therapy at progression. The primary objective was to describe time to progression and overall survival after re-treatment. Results Overall across several Italian oncological Institutions we found 30 patients affected by advanced mesothelioma, in progression after a 6-month lasting clinical benefit following a first-line treatment with cisplatin and pemetrexed, and re-challenged with a pemetrexed-based therapy. In these patients we found a disease control rate of 66%, with reduction of pain in 43% of patients. Overall time to progression and survival were promising for a second-line setting of patients with advanced mesothelioma, being 5.1 and 13.6 months, respectively. Conclusions In our opinion, when a patient has a long-lasting benefit from previous treatment with pemetrexed combined with a platin compound, the same treatment should be offered at progression.

  12. Cosmos, an international center for advanced studies

    Science.gov (United States)

    Ryzhov, Iurii; Alifanov, Oleg; Sadin, Stanley; Coleman, Paul

    1990-01-01

    The concept of Cosmos, a Soviet operating center for aerospace activities, is presented. The main Cosmos participants are the Institute for Aerospace Education, the Institute for Research and Commercial Development, and the Department of Space Policy and Socio-Economic Studies. Cosmos sponsors a number of educational programs, basic research, and studies of the social impact of space-related technologies.

  13. A multi-institutional Stellarator Configuration Study

    Science.gov (United States)

    Gates, David

    2017-10-01

    A multi-institutional study aimed at mapping the space of quasi-axisymmetric stellarators has begun. The goal is to gain improved understanding of the dependence of important physics and engineering parameters (e.g. bootstrap current, stability, coil complexity, etc.) on plasma shape (average elongation, aspect ratio, number of periods). In addition, the stellarator optimization code STELLOPT will be upgraded with new capabilities such as improved coil design algorithms such as COILOPT + + and REGCOIL, divertor optimization options, equilibria with islands using the SPEC code, and improved bootstrap current calculations with the SFINCS code. An effort is underway to develop metrics for divertor optimization. STELLOPT has also had numerous improvements to numerical algorithms and parallelization capabilities. Simultaneously, we also are pursuing the optimization of turbulent transport according to the method of proxy functions. Progress made to date includes an elongation scan on quasi-axisymmetric equilibria and an initial comparison between the SFINCS code and the BOOTSJ calculation of bootstrap current currently available in STELLOPT. Further progress on shape scans and subsequent physics analysis will be reported. The status of the STELLOPT upgrades will be described. The eventual goal of this exercise is to identify attractive configurations for future US experimental facilities.. This work is supported by US DoE Contract Number DE-AC02-09CH11466.

  14. National Institutes of Health Pathways to Prevention Workshop: Advancing Research to Prevent Youth Suicide.

    Science.gov (United States)

    Little, Todd D; Roche, Kathleen M; Chow, Sy-Miin; Schenck, Anna P; Byam, Leslie-Ann

    2016-12-06

    The National Institutes of Health (NIH) Pathways to Prevention Workshop "Advancing Research to Prevent Youth Suicide" was cosponsored by the NIH Office of Disease Prevention, National Institute of Mental Health, National Institute on Drug Abuse, and National Center for Complementary and Integrative Health. A multidisciplinary working group developed the agenda, and an evidence-based practice center prepared an evidence report that addressed data systems relevant to suicide prevention efforts through a contract with the Agency for Healthcare Research and Quality. During the workshop, experts discussed the evidence and participants commented during open forums. After considering the data from the evidence report, expert presentations, and public comments, an independent panel prepared a draft report that was posted on the NIH Office of Disease Prevention Web site for 5 weeks for public comment. This abridged version of the final report provides a road map for optimizing youth suicide prevention efforts by highlighting strategies for guiding the next decade of research in this area. These strategies include recommendations for improving data systems, enhancing data collection and analysis methods, and strengthening the research and practice community.

  15. Advanced satellite servicing facility studies

    Science.gov (United States)

    Qualls, Garry D.; Ferebee, Melvin J., Jr.

    1988-01-01

    A NASA-sponsored systems analysis designed to identify and recommend advanced subsystems and technologies specifically for a manned Sun-synchronous platform for satellite management is discussed. An overview of system design, manned and unmanned servicing facilities, and representative mission scenarios are given. Mission areas discussed include facility based satellite assembly, checkout, deployment, refueling, repair, and systems upgrade. The ferrying of materials and consumables to and from manufacturing platforms, deorbit, removal, repositioning, or salvage of satellites and debris, and crew rescue of any other manned vehicles are also examined. Impacted subsytems discussed include guidance navigation and control, propulsion, data management, power, thermal control, structures, life support, and radiation management. In addition, technology issues which would have significant impacts on the system design are discussed.

  16. A case study of a Cuban government institution

    International Nuclear Information System (INIS)

    Nunez, A.L.; Vazquez, A.; Cruz Cabrera, L.

    2004-01-01

    The aim of this contribution is to present a case study on the partial implementation of a knowledge management system in an institution. In this case the knowledge management has been directed toward the best performance of the organization. The tool used in case study can be implemented at any institution, including institutions of nuclear or radiological profiles. (author)

  17. Conformal Radiotherapy in the Treatment of Advanced Juvenile Nasopharyngeal Angiofibroma With Intracranial Extension: An Institutional Experience

    International Nuclear Information System (INIS)

    Chakraborty, Santam; Ghoshal, Sushmita; Patil, Vijay Maruti; Oinam, Arun Singh; Sharma, Suresh C.

    2011-01-01

    Purpose: To describe the results of conformal radiotherapy in advanced juvenile nasopharyngeal angiofibroma in a tertiary care institution. Methods and Materials: Retrospective chart review was conducted for 8 patients treated with conformal radiotherapy between 2006 and 2009. The median follow-up was 17 months. All patients had Stage IIIB disease with intracranial extension. Radiotherapy was considered as treatment because patients were deemed inoperable owing to extensive intracranial/intraorbital extension or proximity to optic nerve. All but 1 patient were treated with intensity-modulated radiotherapy using seven coplanar fields. Median (range) dose prescribed was 39.6 (30-46) Gy. Actuarial analysis of local control and descriptive analysis of toxicity profile was conducted. Results: Despite the large and complex target volume (median planning target volume, 292 cm 3 ), intensity-modulated radiotherapy achieved conformal dose distributions (median van't Reit index, 0.66). Significant sparing of the surrounding organs at risk was obtained. No significant Grade 3/4 toxicities were experienced during or after treatment. Actual local control at 2 years was 87.5%. One patient died 1 month after radiotherapy secondary to massive epistaxis. The remaining 7 patients had progressive resolution of disease and were symptom-free at last follow-up. Persistent rhinitis was the only significant toxicity, seen in 1 patient. Conclusions: Conformal radiotherapy results in good local control with minimal acute and late side effects in juvenile nasopharyngeal angiofibromas, even in the presence of advanced disease.

  18. A Study of Translation Institutional Ethics

    Institute of Scientific and Technical Information of China (English)

    LuoXianfeng; ZhouJin

    2017-01-01

    Traditional translation ethics characterized by translators' ethics cannot provide a strong moral support to the translation practice,or guarantee the moral requirement towards translation activities in the social transformation caused by the market economy,because it does not have the power of punishment.Translation institutional ethics,however,a new form of translation ethics,integrates the translation ethic norm,translation regulations and relative laws together.As an inevitable outcome in the new era,it can escort the orderly and healthy translation activities.Its purpose is to strengthen the translators' moral consciousness,to sublimate their moral notions and to transfer from heteronomy to autonomy.

  19. Advanced Texas Studies: Curriculum Guide.

    Science.gov (United States)

    Harlandale Independent School District, San Antonio, TX. Career Education Center.

    The guide is arranged in vertical columns relating curriculum concepts in Texas studies to curriculum performance objectives, career concepts and career performance objectives, suggested teaching methods, and audio-visual and resource materials. Career information is included on 24 related occupations. Space is provided for teachers' notes which…

  20. The Advanced Study of Gymnastics.

    Science.gov (United States)

    Salmela, John H., Ed.

    The sport of artistic gymnastics is viewed from a multidisciplinary point of view. The training, performance, and judgment of the sport undergo specialized study of interest to sport scientists, teachers, coaches, and athletes. Organized into five major sections, the book presents such themes as the psychological, physiological, biomechanical,…

  1. Identifying the Local Impacts of National ATE Centers on Their Host Institutions: An Exploratory Study

    Science.gov (United States)

    Henderson, Charles; Fynewever, Herb; Petcovic, Heather; Bierema, Andrea

    2012-01-01

    The purpose of this study is to identify the local impacts of national advanced technological education (ATE) centers on their host institutions. A sample of three mature, national ATE centers are chosen, with each center serving as a case for a mixed-methods, collective case study research design. Results, drawn from interviews and surveys,…

  2. Advanced commercial Tokamak optimization studies

    International Nuclear Information System (INIS)

    Whitley, R.H.; Berwald, D.H.; Gordon, J.D.

    1985-01-01

    Our recent studies have concentrated on developing optimal high beta (bean-shaped plasma) commercial tokamak configurations using TRW's Tokamak Reactor Systems Code (TRSC) with special emphasis on lower net electric power reactors that are more easily deployable. A wide range of issues were investigated in the search for the most economic configuration: fusion power, reactor size, wall load, magnet type, inboard blanket and shield thickness, plasma aspect ratio, and operational β value. The costs and configurations of both steady-state and pulsed reactors were also investigated. Optimal small and large reactor concepts were developed and compared by studying the cost of electricity from single units and from multiplexed units. Multiplexed units appear to have advantages because they share some plant equipment and have lower initial capital investment as compared to larger single units

  3. Analyzing the Relationship of Geographic Mobility and Institutional Prestige to Career Advancement of Women in Academic Medicine Pursuing Midcareer-, Senior-, or Executive-Level Administrative Positions: Implications for Career Advancement Strategies

    Science.gov (United States)

    McLean, Marsha Renee

    2010-01-01

    The purpose of this study was to explore the relationship of geographic mobility and institutional prestige to career advancement defined as administrative promotions of women seeking midcareer-, senior-, or executive-level positions at academic health centers (AHCs) and their medical schools or in non-AHC related medical schools in the United…

  4. NRC review of Electric Power Research Institute's Advanced Light Reactor Utility Requirements Document - Program summary, Project No. 669

    International Nuclear Information System (INIS)

    1992-08-01

    The staff of the US Nuclear Regulatory Commission has prepared Volume 1 of a safety evaluation report (SER), ''NRC Review of Electric Power Research Institute's Advanced Light Water Reactor Utility Requirements Document -- Program Summary,'' to document the results of its review of the Electric Power Research Institute's ''Advanced Light Water Reactor Utility Requirements Document.'' This SER provides a discussion of the overall purpose and scope of the Requirements Document, the background of the staff's review, the review approach used by the staff, and a summary of the policy and technical issues raised by the staff during its review

  5. Research Institute for Advanced Computer Science: Annual Report October 1998 through September 1999

    Science.gov (United States)

    Leiner, Barry M.; Gross, Anthony R. (Technical Monitor)

    1999-01-01

    The Research Institute for Advanced Computer Science (RIACS) carries out basic research and technology development in computer science, in support of the National Aeronautics and Space Administration's missions. RIACS is located at the NASA Ames Research Center (ARC). It currently operates under a multiple year grant/cooperative agreement that began on October 1, 1997 and is up for renewal in the year 2002. ARC has been designated NASA's Center of Excellence in Information Technology. In this capacity, ARC is charged with the responsibility to build an Information Technology Research Program that is preeminent within NASA. RIACS serves as a bridge between NASA ARC and the academic community, and RIACS scientists and visitors work in close collaboration with NASA scientists. RIACS has the additional goal of broadening the base of researchers in these areas of importance to the nation's space and aeronautics enterprises. RIACS research focuses on the three cornerstones of information technology research necessary to meet the future challenges of NASA missions: (1) Automated Reasoning for Autonomous Systems. Techniques are being developed enabling spacecraft that will be self-guiding and self-correcting to the extent that they will require little or no human intervention. Such craft will be equipped to independently solve problems as they arise, and fulfill their missions with minimum direction from Earth. (2) Human-Centered Computing. Many NASA missions require synergy between humans and computers, with sophisticated computational aids amplifying human cognitive and perceptual abilities; (3) High Performance Computing and Networking Advances in the performance of computing and networking continue to have major impact on a variety of NASA endeavors, ranging from modeling and simulation to data analysis of large datasets to collaborative engineering, planning and execution. In addition, RIACS collaborates with NASA scientists to apply information technology research to

  6. Locally advanced cervix cancer: chemotherapy prior to definitive surgery or radiotherapy. A single institutional experience

    International Nuclear Information System (INIS)

    MacLeod, C.; O'Donnell, A.; Tattersall, M.H.N.; Dalrymple, C.; Firth, I.

    2001-01-01

    Primary or neoadjuvant chemotherapy prior to definitive local therapy has potential advantages for locally advanced cervix cancer. It can down stage a cancer and allow definitive local therapy to be technically possible (surgery), or potentially more effective (radiotherapy). It can also eradicate subclinical systemic metastases. This report reviews a single institution's experience of neoadjuvant chemotherapy prior to definitive local therapy for cervix cancer over a 13-year period. One hundred and six patients were treated with this intent. The patients were analysed for their response to chemotherapy, treatment received, survival, relapse and toxicity. The chemotherapy was feasible and the majority of patients had a complete or partial response (58.5%). Eight patients did not proceed to local treatment. Forty-six patients had definitive surgery and 52 had definitive radiotherapy. The 5-year overall survival was 27% and the majority of patients died with disease. The first site of relapse was usually in the pelvis (46.2%). Late complications that required ongoing medical therapy (n = 6) or surgical intervention (n = 2) were recorded in eight patients (7.5%). On univariate analysis stage (P= 0.04), tumour size (P = 0.01), lymph node status (P=0.003), response to chemotherapy (P = 0.045) and treatment (P = 0.003) were all significant predictors of survival. On multivariate analysis, tumour size (P < 0.0001) and nodal status (P = 0.02) were significant predictors of survival. Despite the impressive responses to chemotherapy of advanced cervix cancer, there is evidence from randomized trials that it does not improve or compromise survival prior to radiotherapy. As its role prior to surgery remains unclear, it should not be used in this setting outside a prospective randomized trial. Copyright (2001) Blackwell Science Pty Ltd

  7. Advanced Demonstration and Test Reactor Options Study

    Energy Technology Data Exchange (ETDEWEB)

    Petti, David Andrew [Idaho National Lab. (INL), Idaho Falls, ID (United States); Hill, R. [Argonne National Lab. (ANL), Argonne, IL (United States); Gehin, J. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Gougar, Hans David [Idaho National Lab. (INL), Idaho Falls, ID (United States); Strydom, Gerhard [Idaho National Lab. (INL), Idaho Falls, ID (United States); Heidet, F. [Argonne National Lab. (ANL), Argonne, IL (United States); Kinsey, J. [Idaho National Lab. (INL), Idaho Falls, ID (United States); Grandy, Christopher [Argonne National Lab. (ANL), Argonne, IL (United States); Qualls, A. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Brown, Nicholas [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Powers, J. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Hoffman, E. [Argonne National Lab. (ANL), Argonne, IL (United States); Croson, D. [Idaho National Lab. (INL), Idaho Falls, ID (United States)

    2017-01-01

    Global efforts to address climate change will require large-scale decarbonization of energy production in the United States and elsewhere. Nuclear power already provides 20% of electricity production in the United States (U.S.) and is increasing in countries undergoing rapid growth around the world. Because reliable, grid-stabilizing, low emission electricity generation, energy security, and energy resource diversity will be increasingly valued, nuclear power’s share of electricity production has a potential to grow. In addition, there are non electricity applications (e.g., process heat, desalination, hydrogen production) that could be better served by advanced nuclear systems. Thus, the timely development, demonstration, and commercialization of advanced nuclear reactors could diversify the nuclear technologies available and offer attractive technology options to expand the impact of nuclear energy for electricity generation and non-electricity missions. The purpose of this planning study is to provide transparent and defensible technology options for a test and/or demonstration reactor(s) to be built to support public policy, innovation and long term commercialization within the context of the Department of Energy’s (DOE’s) broader commitment to pursuing an “all of the above” clean energy strategy and associated time lines. This planning study includes identification of the key features and timing needed for advanced test or demonstration reactors to support research, development, and technology demonstration leading to the commercialization of power plants built upon these advanced reactor platforms. This planning study is consistent with the Congressional language contained within the fiscal year 2015 appropriation that directed the DOE to conduct a planning study to evaluate “advanced reactor technology options, capabilities, and requirements within the context of national needs and public policy to support innovation in nuclear energy

  8. Advanced Demonstration and Test Reactor Options Study

    International Nuclear Information System (INIS)

    Petti, David Andrew; Hill, R.; Gehin, J.; Gougar, Hans David; Strydom, Gerhard; Heidet, F.; Kinsey, J.; Grandy, Christopher; Qualls, A.; Brown, Nicholas; Powers, J.; Hoffman, E.; Croson, D.

    2017-01-01

    Global efforts to address climate change will require large-scale decarbonization of energy production in the United States and elsewhere. Nuclear power already provides 20% of electricity production in the United States (U.S.) and is increasing in countries undergoing rapid growth around the world. Because reliable, grid-stabilizing, low emission electricity generation, energy security, and energy resource diversity will be increasingly valued, nuclear power's share of electricity production has a potential to grow. In addition, there are non electricity applications (e.g., process heat, desalination, hydrogen production) that could be better served by advanced nuclear systems. Thus, the timely development, demonstration, and commercialization of advanced nuclear reactors could diversify the nuclear technologies available and offer attractive technology options to expand the impact of nuclear energy for electricity generation and non-electricity missions. The purpose of this planning study is to provide transparent and defensible technology options for a test and/or demonstration reactor(s) to be built to support public policy, innovation and long term commercialization within the context of the Department of Energy's (DOE's) broader commitment to pursuing an 'all of the above' clean energy strategy and associated time lines. This planning study includes identification of the key features and timing needed for advanced test or demonstration reactors to support research, development, and technology demonstration leading to the commercialization of power plants built upon these advanced reactor platforms. This planning study is consistent with the Congressional language contained within the fiscal year 2015 appropriation that directed the DOE to conduct a planning study to evaluate 'advanced reactor technology options, capabilities, and requirements within the context of national needs and public policy to support innovation in nuclear energy'. Advanced reactors are

  9. Research Review of the Institute of African Studies

    African Journals Online (AJOL)

    Please note: As of 2013 the Research Review of the Institute of African Studies is now publishing under the title Contemporary Journal of African Studies. You can view the CJAS pages on AJOL here: http://www.ajol.info/index.php/contjas/index. The Research Review of the Institute of African Studies at the University of ...

  10. Journal of Development and Communication Studies: Advanced ...

    African Journals Online (AJOL)

    PROMOTING ACCESS TO AFRICAN RESEARCH ... Journal of Development and Communication Studies: Advanced Search ... of characters; e.g., soci* morality would match documents containing "sociological" or "societal" .... Journal of Business and Administrative Studies, Journal of Business Research, Journal of Child ...

  11. Literacy Skills Development for Tertiary Institutions: A Case Study of ...

    African Journals Online (AJOL)

    Literacy Skills Development for Tertiary Institutions: A Case Study of the University of Calabar. ... These were drawn from five faculties, namely Education, Social Sciences, Law, Arts and Agriculture. The study observed that there is a ... more literacy skills. Key Words: Literacy skills, university, Nigeria, tertiary institution ...

  12. NATO Advanced Study Institute on Atoms in Unusual Situations

    CERN Document Server

    1986-01-01

    Atomic Physics is certainly the oldest field in which Quantum Mechanics has been used and has provided the most significant proofs of this new theory. Most of the basic concepts, except those more recently developed in field quantization, have been understood for quite a time. Atomic Physics began to serve as a basis for other fields such as molecu­ lar, solid state or nuclear physics. A renewal of interest in Atomic Physics began in the sixties, after the discovery of Quantum Electro­ dynamics, and later when it provided some basic tests of fundamental questions like parity violation, time reversal or Dirac theory. More recently the development of new technologies led to the ex­ ploration of very extreme cases in which the most secrete aspects of atoms have been observed. - Rydberg states where the atoms are so big that they can be described by classical theories; - Heavy or super-heavy ions or exotic atoms where unknown QED or relativistic effects can be observed (very heavy hydrogenlike or heliu...

  13. NATO Advanced Study Institute on Disorder and Fracture

    CERN Document Server

    Roux, S; Guyon, E

    1990-01-01

    Fracture, and particularly brittle fracture, is a good example of an instability. For a homogeneous solid, subjected to a uniform stress field, a crack may appear anywhere in the structure once the threshold stress is reached. However, once a crack has been nucleated in some place, further damage in the solid will in most cases propagate from the initial crack, and not somewhere else in the solid. In this sense fracture is an unstable process. This property makes the process extremely sensitive to any heterogeneity present in the medium, which selects the location of the first crack nucleated. In particular, fracture appears to be very sensitive to disorder, which can favor or impede local cracks. Therefore, in most realistic cases, a good description of fracture mechanics should include the effect of disorder. Recently this need has motivated work in this direction starting from the usual description of fracture mechanics. Parallel with this first trend, statistical physics underwent a very important develop...

  14. Virtual Nonlinear Multibody Systems, NATO Advanced Study Institute. Volume 2

    National Research Council Canada - National Science Library

    Schiehlen, W. O

    2002-01-01

    .... The virtual prototyping and dynamic modeling of such systems are, from an economical point of view, perspective fields of scientific investigations having in mind the huge expenses for their design...

  15. NATO Advanced Study Institute on Chaotic Dynamics : Theory and Practice

    CERN Document Server

    1992-01-01

    Many conferences, meetings, workshops, summer schools and symposia on nonlinear dynamical systems are being organized these days, dealing with a great variety of topics and themes -classical and quantum, theoretical and experimental. Some focus on integrability, or discuss the mathematical foundations of chaos. Others explore the beauty of fractals, or examine endless possibilities of applications to problems of physics, chemistry, biology and other sciences. A new scientific discipline has thus emerged, with its own distinct philosophical viewpoint and an impressive arsenal of new methods and techniques, which may be called Chaotic Dynamics. Perhaps its most outstanding achievement so far has been to shed new light on many long­ standing issues involving complicated, irregular or "chaotic" nonlinear phenomena. The concepts of randomness, complexity and unpredictability have been critically re-examined and the fundamental importance of scaling, self-similarity and sensitive dependence on parameters a...

  16. Research Review of the Institute of African Studies: Advanced Search

    African Journals Online (AJOL)

    Search tips: Search terms are case-insensitive; Common words are ignored; By default only articles containing all terms in the query are returned (i.e., AND is implied); Combine multiple words with OR to find articles containing either term; e.g., education OR research; Use parentheses to create more complex queries; e.g., ...

  17. NATO Advanced Study Institute on New Aspects of Nuclear Dynamics

    CERN Document Server

    Huberts, P

    1989-01-01

    The 1988 Summer School on New Aspects of Nuclear Dynamics took place in the style that by now has become a tradition: a series of lectures by well known scientists on modem topics of nuclear physics, where special emphasis is placed on the didactic aspects of the lectures. In the past few years, we have witnessed a rapid evolution of the field of nuclear physics towards novel directions of research. This development is accompanied by the construction of some of the largest experimental facilities ever built for nuclear research. The subjects covered by the Summer School focussed on two main issues currently under active investigation and which will be pursued with the new facilities: the transition from nucleonic to quark degrees of freedom in the decription of nuclear reactions, and the behavior of nuclear matter as one approaches extreme densities and temperatures. These topics in many respects go beyond traditional nuclear physics and the speakers therefore also included high energy physicists. From the re...

  18. NATO Advanced Study Institute on Physics of Submicron Semiconductor Devices

    CERN Document Server

    Ferry, David; Jacoboni, C

    1988-01-01

    The papers contained in the volume represent lectures delivered as a 1983 NATO ASI, held at Urbino, Italy. The lecture series was designed to identify the key submicron and ultrasubmicron device physics, transport, materials and contact issues. Nonequilibrium transport, quantum transport, interfacial and size constraints issues were also highlighted. The ASI was supported by NATO and the European Research Office. H. L. Grubin D. K. Ferry C. Jacoboni v CONTENTS MODELLING OF SUB-MICRON DEVICES.................. .......... 1 E. Constant BOLTZMANN TRANSPORT EQUATION... ... ...... .................... 33 K. Hess TRANSPORT AND MATERIAL CONSIDERATIONS FOR SUBMICRON DEVICES. . .. . . . . .. . . . .. . .. . .... ... .. . . . .. . . . .. . . . . . . . . . . 45 H. L. Grubin EPITAXIAL GROWTH FOR SUB MICRON STRUCTURES.................. 179 C. E. C. Wood INSULATOR/SEMICONDUCTOR INTERFACES.......................... 195 C. W. Wilms en THEORY OF THE ELECTRONIC STRUCTURE OF SEMICONDUCTOR SURFACES AND INTERFACES...................

  19. NATO Advanced Study Institute on From molecules to medicines

    CERN Document Server

    Sussman, Joel L; From Molecules to Medicines

    2009-01-01

    The synergism played by crystallography and drug discovery is the central focus of this volume which comprises papers presented at the 40th Erice Course held from 28 May to 8 June 2008. A key theme throughout the book is the dependence of modern structural science on multiple experimental and computational techniques, and it is the development of these techniques and their integration that will take us forward in the future.

  20. NATO Advanced Study Institute on Evolving Methods for Macromolecular Gystallography

    CERN Document Server

    Read, Randy J

    2007-01-01

    X-ray crystallography is the pre-eminent technique for visualizing the structures of macromolecules at atomic resolution. These structures are central to understanding the detailed mechanisms of biological processes, and to discovering novel therapeutics using a structure-based approach. As yet, structures are known for only a small fraction of the proteins encoded by human and pathogenic genomes. To counter the myriad modern threats of disease, there is an urgent need to determine the structures of the thousands of proteins whose structure and function remain unknown. This volume draws on the expertise of leaders in the field of macromolecular crystallography to illuminate the dramatic developments that are accelerating progress in structural biology. Their contributions span the range of techniques from crystallization through data collection, structure solution and analysis, and show how modern high-throughput methods are contributing to a deeper understanding of medical problems.

  1. Ford Partnership for Advanced Studies (Ford PAS)

    Science.gov (United States)

    Carrier, Cheryl

    2006-01-01

    This article features the Ford Partnership for Advanced Studies (Ford PAS) program that helps students gain knowledge about real-life business issues. Ford PAS is an educational program that combines college-prep academics with the critical 21st century skills students will need to succeed in college and in the workplace. The Ford PAS program uses…

  2. Institutional Support : African Technology Policy Studies - Tanzania ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    African Technology Policy Studies - Tanzania (ATPS-Tanzania) was registered as a national nongovernmental organization in 2001. ... While resource flows to ATPS-Tanzania from ATPS headquarters in Nairobi were reliable, the organization produced a larger volume of research outputs than most other ATPS national ...

  3. Neo-Institutional Approach to the Study of Electronic Government

    Directory of Open Access Journals (Sweden)

    Yan I. Vaslavskiy

    2016-01-01

    Full Text Available The article is devoted to the neo-institutional approach as a methodological basis in the study of electronic government. In this article substantiates the choice of neo-institutional approach to the study of the processes of implementation of information and communication technologies in the activity of state institutions, analyzes the differences of neoinstitutionalism from traditional institutional approach, considers the features of the different directions of neo-institutionalism, namely sociological, historical and rational choice theory. Attention is paid to the reasons for the renewed interest in political institutions in political science. The article emphasizes the importance of considering the electronic government as an institution, and the conditions for its implementation in the Russian political system as the institutional environment. The authors pay special attention to the variety of sociological neo-institutionalism, used, in addition to political science in sociology of organizations. The article substantiates the value of using sociological institutionalism to explore the electronic government based on a comparative analysis of e-government projects in Russia and abroad and explores its heuristic capabilities. It examines the impact of the system of norms and values of the institutional environment on the processes of formation and development of electronic government in Russia. The research capacity of this theory is due to the fact that it allows us to trace the reasons for copying and replication of inefficient practices and organizational and management schemes, to identify the factors impeding innovation use by the state of electronic interaction technologies. It is emphasized that the use of the theory of institutional isomorphism is useful in the sphere of implementation of electronic technologies, in which a key role play pluralism, horizontal managerial communication, inter-agency coordination.

  4. IMMUNOPHENOTYPING IN ACUTE LEUKAEMIA- AN INSTITUTIONAL STUDY

    Directory of Open Access Journals (Sweden)

    Aparajita Das

    2018-02-01

    Full Text Available BACKGROUND Leukaemias are biologically a diverse group of disorders with differences in their morphology, antigen expression, chromosomal and molecular abnormalities, response to treatment, and prognosis. The main objective of the study was to compare morphological and flowcytometric diagnosis in patients diagnosed with acute leukaemia. MATERIALS AND METHODS The prospective study was carried out at S.C.B. Medical College and hospital, Cuttack, in department of Pathology and Clinical haematology, for the period of November 2015- November 2017. The findings were based on 100 patients who underwent both flow cytometry and peripheral smear/bone marrow morphology tests for diagnosis of acute leukaemia. RESULTS Using the peripheral smear/bone marrow morphology, 27% patients had ALL-L1, 38% had ALL-L2, 05% had AML-M1, 21% had AML-M2, 06% had AML-M3, 02% had AML-M4, and 01% had AML-M5. Immunophenotyping by flow cytometry confirms 50% patients to be B-ALL, 07% to be T-ALL, 32% AML, 08% APML/AML-M3, and 03% to be MPAL. There was a concordance between the morphological and flowcytometry of 88% in ALL, 91% in AML, 75% in APML, but, no concordance at all for MPAL. CONCLUSION Hence, flowcytometry is mandatory in all cases of acute leukemia, to confirm a definite diagnosis, as treatment nowadays is target oriented.

  5. Arguments for the Study of Institutionalism and Institutional Reform in Romania

    Directory of Open Access Journals (Sweden)

    Ion Pohoata

    2006-07-01

    Full Text Available The study and comprehension of institutions – viewed as written and unwritten constraints (rules initiated by people to create and improve human interaction – represents the key to understand the success (and failure of contemporary economies and societies. The framework inspired by institutions to which people dedicated maximum energy and talent also explains the different levels of efficiency in modern times. The founders of institutionalism – in its old and new versions – explain, for example, that human endeavour for social improvement led to the appearance of Law, private ownership, contract and market. For Romania, such explanations are inspirational and of utmost necessity in presenting the real context and in finding the necessary measures and directions towards desired progress.

  6. Arguments for the Study of Institutionalism and Institutional Reform in Romania

    Directory of Open Access Journals (Sweden)

    Ion Pohoata

    2006-09-01

    Full Text Available The study and comprehension of institutions – viewed as written and unwritten constraints (rules initiated by people to create and improve human interaction – represents the key to understand the success (and failure of contemporary economies and societies. The framework inspired by institutions to which people dedicated maximum energy and talent also explains the different levels of efficiency in modern times. The founders of institutionalism – in its old and new versions – explain, for example, that human endeavour for social improvement led to the appearance of Law, private ownership, contract and market. For Romania, such explanations are inspirational and of utmost necessity in presenting the real context and in finding the necessary measures and directions towards desired progress.

  7. Research Advances at the Institute for Nutritional Sciences at Shanghai, China12

    Science.gov (United States)

    Chen, Yan; Lin, Xu; Liu, Yong; Xie, Dong; Fang, Jing; Le, Yingying; Ke, Zunji; Zhai, Qiwei; Wang, Hui; Guo, Feifan; Wang, Fudi; Liu, Yi

    2011-01-01

    Nutrition-related health issues have emerged as a major threat to public health since the rebirth of the economy in China starting in the 1980s. To meet this challenge, the Chinese Academy of Sciences established the Institute for Nutritional Sciences (INS) at Shanghai, China ∼8 y ago. The mission of the INS is to apply modern technologies and concepts in nutritional research to understand the molecular mechanism and provide means of intervention in the combat against nutrition-related diseases, including type 2 diabetes, metabolic syndrome, obesity, cardiovascular diseases, and many types of cancers. Through diligent and orchestrated efforts by INS scientists, graduate students, and research staff in the past few years, the INS has become the leading institution in China in the areas of basic nutritional research and metabolic regulation. Scientists at the INS have made important progress in many areas, including the characterization of genetic and nutritional properties of the Chinese population, metabolic control associated with nutrient sensing, molecular mechanisms underlying glucose and lipid metabolism, regulation of metabolism by adipokines and inflammatory pathways, disease intervention using functional foods or extracts of Chinese herbs, and many biological studies related to carcinogenesis. The INS will continue its efforts in understanding the optimal nutritional needs for Chinese people and the molecular causes associated with metabolic diseases, thus paving the way for effective and individualized intervention in the future. This review highlights the major research endeavors undertaken by INS scientists in recent years. PMID:22332084

  8. Advanced Cell Development and Degradation Studies

    International Nuclear Information System (INIS)

    O'Brien, J.E.; Stoots, C.M.; Herring, J.S.; O'Brien, R.C.; Condie, K.G.; Sohal, M.; Housley, G.K.; Hartvigsen, J.J.; Larsen, D.; Tao, G.; Yildiz, B.; Sharma, V.; Singh, P.; Petigny, N.; Cable, T.L.

    2010-01-01

    The Idaho National Laboratory (INL) has been researching the application of solid-oxide electrolysis cells for large-scale hydrogen production from steam over a temperature range of 800 to 900 C. From 2003-2009, this work was sponsored by the DOE Nuclear Hydrogen Initiative (NHI). Starting in 2010, the HTE research program has been sponsored by the Next Generation Nuclear Plant (NGNP) program. HTSE research priorities in FY10 are centered on understanding and reducing cell and stack performance degradation to an acceptable level to advance the technology readiness level of HTSE and to justify further large-scale demonstration activities. This report provides a summary of our FY10 experimental program, which has been focused on advanced cell and stack development and degradation studies. Advanced cell and stack development activities are under way at five technology partners: MSRI, Versa Power, Ceramatec, NASA Glenn, and St. Gobain. Performance evaluation of the advanced technology cells and stacks has been performed by the technology partners, by MIT and the University of Connecticut and at the INL HTE Laboratory. Summaries of these development activities and test results are presented.

  9. Advanced Cell Development and Degradation Studies

    Energy Technology Data Exchange (ETDEWEB)

    J. E. O' Brien; C. M. Stoots; J. S. Herring; R. C. O' Brien; K. G. Condie; M. Sohal; G. K. Housley; J. J. Hartvigsen; D. Larsen; G. Tao; B. Yildiz; V. Sharma; P. Singh; N. Petigny; T. L. Cable

    2010-09-01

    The Idaho National Laboratory (INL) has been researching the application of solid-oxide electrolysis cells for large-scale hydrogen production from steam over a temperature range of 800 to 900ºC. From 2003 – 2009, this work was sponsored by the DOE Nuclear Hydrogen Initiative (NHI). Starting in 2010, the HTE research program has been sponsored by the Next Generation Nuclear Plant (NGNP) program. HTSE research priorities in FY10 are centered on understanding and reducing cell and stack performance degradation to an acceptable level to advance the technology readiness level of HTSE and to justify further large-scale demonstration activities. This report provides a summary of our FY10 experimental program, which has been focused on advanced cell and stack development and degradation studies. Advanced cell and stack development activities are under way at five technology partners: MSRI, Versa Power, Ceramatec, NASA Glenn, and St. Gobain. Performance evaluation of the advanced technology cells and stacks has been performed by the technology partners, by MIT and the University of Connecticut and at the INL HTE Laboratory. Summaries of these development activities and test results are presented.

  10. Achieving and sustaining profound institutional change in healthcare: case study using neo-institutional theory.

    Science.gov (United States)

    Macfarlane, Fraser; Barton-Sweeney, Cathy; Woodard, Fran; Greenhalgh, Trisha

    2013-03-01

    Change efforts in healthcare sometimes have an ambitious, whole-system remit and seek to achieve fundamental changes in norms and organisational culture rather than (or as well as) restructuring the service. Long-term evaluation of such initiatives is rarely undertaken. We report a secondary analysis of data from an evaluation of a profound institutional change effort in London, England, using a mixed-method longitudinal case study design. The service had received £15 million modernisation funding in 2004, covering multiple organisations and sectors and overseen by a bespoke management and governance infrastructure that was dismantled in 2008. In 2010-11, we gathered data (activity statistics, documents, interviews, questionnaires, site visits) and compared these with data from 2003 to 2008. Data analysis was informed by neo-institutional theory, which considers organisational change as resulting from the material-resource environment and three 'institutional pillars' (regulative, normative and cultural-cognitive), enacted and reproduced via the identities, values and activities of human actors. Explaining the long-term fortunes of the different components of the original programme and their continuing adaptation to a changing context required attention to all three of Scott's pillars and to the interplay between macro institutional structures and embedded human agency. The paper illustrates how neo-institutional theory (which is typically used by academics to theorise macro-level changes in institutional structures over time) can also be applied at a more meso level to inform an empirical analysis of how healthcare organisations achieve change and what helps or hinders efforts to sustain those changes. Copyright © 2013 Elsevier Ltd. All rights reserved.

  11. USAF Institute for National Security Studies 1998 Research Results Conference

    National Research Council Canada - National Science Library

    1998-01-01

    The USAF Institute for National Security Studies (INSS), in cooperation with HQ USAF Nuclear and Counterproliferation Directorate, sponsored its 6th annual Research Results Conference on 19 - 20 November 1998...

  12. Pressure Safety: Advanced Self-Study 30120

    Energy Technology Data Exchange (ETDEWEB)

    Glass, George [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2016-02-29

    Pressure Safety Advance Self-Study (Course 30120) consists of an introduction, five modules, and a quiz. To receive credit in UTrain for completing this course, you must score 80% or better on the 15-question quiz (check UTrain). Directions for initiating the quiz are appended to the end of this training manual. This course contains several links to LANL websites. UTrain might not support active links, so please copy links into the address line in your browser.

  13. 75 FR 76617 - Use of Community Development Loans by Community Financial Institutions To Secure Advances...

    Science.gov (United States)

    2010-12-09

    ...; Transfer of Advances and New Business Activity Regulations AGENCY: Federal Housing Finance Board, Federal... advances and new business activities rules from parts 950 and 980 of the Federal Housing Finance Board... business activity regulation, respectively, from parts 950 and 980 of the Finance Board regulations to...

  14. Developing a clinical trial unit to advance research in an academic institution.

    Science.gov (United States)

    Croghan, Ivana T; Viker, Steven D; Limper, Andrew H; Evans, Tamara K; Cornell, Alissa R; Ebbert, Jon O; Gertz, Morie A

    2015-11-01

    Research, clinical care, and education are the three cornerstones of academic health centers in the United States. The research climate has always been riddled with ebbs and flows, depending on funding availability. During a time of reduced funding, the number and scope of research studies have been reduced, and in some instances, a field of study has been eliminated. Recent reductions in the research funding landscape have led institutions to explore new ways to continue supporting research. Mayo Clinic in Rochester, MN has developed a clinical trial unit within the Department of Medicine, which provides shared resources for many researchers and serves as a solution for training and mentoring new investigators and study teams. By building on existing infrastructure and providing supplemental resources to existing research, the Department of Medicine clinical trial unit has evolved into an effective mechanism for conducting research. This article discusses the creation of a central unit to provide research support in clinical trials and presents the advantages, disadvantages, and required building blocks for such a unit. Copyright © 2015 Mayo Clinic. Published by Elsevier Inc. All rights reserved.

  15. Sunitinib treatment in patients with advanced renal cell cancer: the Brazilian National Cancer Institute (INCA) experience.

    Science.gov (United States)

    Coelho, Rafael Corrêa; Reinert, Tomás; Campos, Franz; Peixoto, Fábio Affonso; de Andrade, Carlos Augusto; Castro, Thalita; Herchenhorn, Daniel

    2016-01-01

    The aim of this study was to assess the impact of sunitinib treatment in a non-screened group of patients with metastatic renal cell cancer (mRCC) treated by the Brazilian Unified Health System (SUS) at a single reference institution. Retrospective cohort study, which evaluated patients with mRCC who received sunitinib between May 2010 and December 2013. Fifty-eight patients were eligible. Most patients were male 41 (71%), with a median age of 58 years. Nephrectomy was performed in 41 (71%) patients with a median interval of 16 months between the surgery and initiation of sunitinib. The most prevalent histological subtype was clear cell carcinoma, present in 52 (91.2%) patients. In 50 patients (86%), sunitinib was the first line of systemic treatment. The main adverse effects were fatigue (57%), hypothyroidism (43%), mucositis (33%) and diarrhea (29%). Grade 3 and 4 adverse effects were infrequent: fatigue (12%), hypertension (12%), thrombocytopenia (7%), neutropenia (5%) and hand-foot syndrome (5%). Forty percent of patients achieved a partial response and 35% stable disease, with a disease control rate of 75%. Median progression free survival was 7.6 months and median overall survival was 14.1 months. Sunitinib treatment was active in the majority of patients, especially those with low and intermediate risk by MSKCC score, with manageable toxicity. Survival rates were inferior in this non-screened population with mRCC treated in the SUS. Copyright© by the International Brazilian Journal of Urology.

  16. Sunitinib treatment in patients with advanced renal cell cancer: the Brazilian National Cancer Institute (INCA experience

    Directory of Open Access Journals (Sweden)

    Rafael Corrêa Coelho

    Full Text Available ABSTRACT Purpose: The aim of this study was to assess the impact of sunitinib treatment in a non-screened group of patients with metastatic renal cell cancer (mRCC treated by the Brazilian Unified Health System (SUS at a single reference institution. Material and Methods: Retrospective cohort study, which evaluated patients with mRCC who received sunitinib between May 2010 and December 2013. Results: Fifty-eight patients were eligible. Most patients were male 41 (71%, with a median age of 58 years. Nephrectomy was performed in 41 (71% patients with a median interval of 16 months between the surgery and initiation of sunitinib. The most prevalent histological subtype was clear cell carcinoma, present in 52 (91.2% patients. In 50 patients (86%, sunitinib was the first line of systemic treatment. The main adverse effects were fatigue (57%, hypothyroidism (43%, mucositis (33% and diarrhea (29%. Grade 3 and 4 adverse effects were infrequent: fatigue (12%, hypertension (12%, thrombocytopenia (7%, neutropenia (5% and hand-foot syndrome (5%. Forty percent of patients achieved a partial response and 35% stable disease, with a disease control rate of 75%. Median progression free survival was 7.6 months and median overall survival was 14.1 months. Conclusion: Sunitinib treatment was active in the majority of patients, especially those with low and intermediate risk by MSKCC score, with manageable toxicity. Survival rates were inferior in this non-screened population with mRCC treated in the SUS.

  17. Academic and Career Advancement for Black Male Athletes at NCAA Division I Institutions

    Science.gov (United States)

    Baker, Ashley R.; Hawkins, Billy J.

    2016-01-01

    This chapter examines the structural arrangements and challenges many Black male athletes encounter as a result of their use of sport for upward social mobility. Recommendations to enhance their preparation and advancement are provided.

  18. Palliative care in advanced gynecological cancers: Institute of palliative medicine experience

    Directory of Open Access Journals (Sweden)

    Sushmita Pathy

    2008-01-01

    Full Text Available Aim: To study the epidemiological profile, clinical symptoms and referral patterns of patients with gynecological malignancy. To evaluate pain symptoms, response to treatment and factors affecting management in patients with advanced gynecological malignancies. Methods: A retrospective analysis was performed of the gynecological malignancy cases registered at the Pain and Palliative Care Clinic, Calicut, over a 12-month period between January 2006 and December 2006.Patient characteristics, symptoms and response to treatment were evaluated in detail. Results: A total of 1813 patients registered, of which 64 had gynecological malignancies. Most of the cases were referred from the Oncology Department of the Calicut Medical College. Fifty-five percent of the patients were unaware of their diagnosis. Psychosocial issues and anxiety were observed in 48%. Insomnia was seen in 52% of the cases. Pain was the most common and most distressing symptom. Adequate pain relief was achieved in only 32% of the patients. Conclusions: The number of gynecological malignancy cases attending the Pain and Palliative Care Clinic is small. Pain is the most common and distressing symptom, with only 32% of the patients achieving adequate pain relief. Poor drug compliance, incomplete assessment of pain and the lack of awareness of morphine therapy were identified as the most common causes for poor pain control.

  19. A comparative study of various advanced fusions

    International Nuclear Information System (INIS)

    Momota, H.; Tomita, Y.; Nomura, Y.

    1983-01-01

    For the purpose of comparing the merits and demerits of various advanced fuel cycles, parametric studies of operation conditions are examined. The effects of nuclear elastic collisions and synchrotron radiation are taken into account. It is found that the high-#betta# Catalyzed DD fuel cycle with the transmutation of fusion-produced tritium into helium-3 is most feasible from the point of view of neutron production and tritium handling. The D-D fuel cycles seem to be less attractive compared to the Catalyzed DD. The p- 11 B and p- 6 Li fusion plasmas hardly attain the plasma Q value relevant to reactors. (author)

  20. Technological advances for studying human behavior

    Science.gov (United States)

    Roske-Hofstrand, Renate J.

    1990-01-01

    Technological advances for studying human behavior are noted in viewgraph form. It is asserted that performance-aiding systems are proliferating without a fundamental understanding of how they would interact with the humans who must control them. Two views of automation research, the hardware view and the human-centered view, are listed. Other viewgraphs give information on vital elements for human-centered research, a continuum of the research process, available technologies, new technologies for persistent problems, a sample research infrastructure, the need for metrics, and examples of data-link technology.

  1. Advanced supersonic propulsion study, phase 4

    Science.gov (United States)

    Howlett, R. A.

    1977-01-01

    Installation characteristics for a Variable Stream Control Engine (VSCE) were studied for three advanced supersonic airplane designs. Sensitivity of the VSCE concept to change in technology projections was evaluated in terms of impact on overall installed performance. Based on these sensitivity results, critical technology requirements were reviewed, resulting in the reaffirmation of the following requirements: low-noise nozzle system; a high performance, low emissions duct burner and main burner; hot section technology; variable geometry components; and propulsion integration features, including an integrated electronic control system.

  2. Twin cities institutional issues study cogenerated hot water district heating

    Energy Technology Data Exchange (ETDEWEB)

    Sundberg, R. E.; Leas, R.; Kolb, J. O.

    1979-01-01

    Community district heating, utilizing hot water produced through electrical/thermal cogeneration, is seen as an integral part of Minnesota's Energy Policy and Conservation Plan. Several studies have been conducted which consider the technical and institutional issues affecting implementation of cogenerated district heating in the Minneapolis and St. Paul Metropolitan Area. The state of the technical art of cogenerated hot water district heating is assumed to be transferable from European experience. Institutional questions relating to such factors as the form of ownership, financing, operation, regulation, and product marketability cannot be transferred from the European experience, and have been the subject of an extensive investigation. The form and function of the Institutional Issues Study, and some of the preliminary conclusions and recommendations resulting from the study are discussed.

  3. Mirror Advanced Reactor Study interim design report

    Energy Technology Data Exchange (ETDEWEB)

    1983-04-01

    The status of the design of a tenth-of-a-kind commercial tandem-mirror fusion reactor is described at the midpoint of a two-year study. When completed, the design is to serve as a strategic goal for the mirror fusion program. The main objectives of the Mirror Advanced Reactor Study (MARS) are: (1) to design an attractive tandem-mirror fusion reactor producing electricity and synfuels (in alternate versions), (2) to identify key development and technology needs, and (3) to exploit the potential of fusion for safety, low activation, and simple disposal of radioactive waste. In the first year we have emphasized physics and engineering of the central cell and physics of the end cell. Design optimization and trade studies are continuing, and we expect additional modifications in the end cells to further improve the performance of the final design.

  4. Mirror Advanced Reactor Study interim design report

    International Nuclear Information System (INIS)

    1983-04-01

    The status of the design of a tenth-of-a-kind commercial tandem-mirror fusion reactor is described at the midpoint of a two-year study. When completed, the design is to serve as a strategic goal for the mirror fusion program. The main objectives of the Mirror Advanced Reactor Study (MARS) are: (1) to design an attractive tandem-mirror fusion reactor producing electricity and synfuels (in alternate versions), (2) to identify key development and technology needs, and (3) to exploit the potential of fusion for safety, low activation, and simple disposal of radioactive waste. In the first year we have emphasized physics and engineering of the central cell and physics of the end cell. Design optimization and trade studies are continuing, and we expect additional modifications in the end cells to further improve the performance of the final design

  5. Institutional solid waste management practices in developing countries. A case study of three academic institutions in Tanzania

    Energy Technology Data Exchange (ETDEWEB)

    Mbuligwe, Stephen E. [Faculty of Lands and Environmental Engineering, Department of Environmental Engineering, University College of Lands and Architectural Studies UCLAS, PO Box 35176, Dar es Salaam (Tanzania, United Republic of)

    2002-05-01

    This paper reports on institutional solid waste management in three Tanzanian institutions. It is noted that there are indeed advantages in managing solid waste at institutional level because of the institutions' unique characteristics that also influence their waste management needs. The paper outlines findings from a yearlong study on institutional solid waste management at three institutions: University of Dar es Salaam (UDSM), University College of Lands and Architectural Studies (UCLAS) and Water Resources Institute (WRI). Surveys and field investigations, including on-site waste measurements and questionnaire surveys were done at UDSM, UCLAS and WRI. The study has revealed, among other things, that per capita waste generation rates, W{sub G} vary between staff and students within each institution as well as among the three institutions. The composition of the waste was found to be predominantly organic in nature, suggesting a strong resource recovery potential in terms of animal feed or production of biogas through anaerobic digestion. Additionally, the W{sub G} was found to vary in line with changes in institutional activities like normal studies, examinations and holidays. The study has shown that resource recovery could greatly enhance solid waste management at the case study institutions.

  6. Development Strategy of Microtakaful Institutions: Case Study Working Group Indonesia

    Directory of Open Access Journals (Sweden)

    Aam Slamet Rusydiana

    2017-07-01

    Full Text Available Indonesia is becoming one of potential countries in microtakaful institutions development. One of the expert in microtakaful is Takmin Working Group. TWG is a group of initiators who have commitment to develop micro takaful in Indonesia. Its members consist ofexperts in Islamic insurance, micro finance and accounting. The research objectives of this study are to identify and analyze the problems faced by TWG in developing of microtakaful institutions and identify the solutions to solve those kinds of problems, by using AnalticHierarchy Process (AHP method. The finding of this study shows the most priority solutions that can be undertake by Takmin Working Group to solve these both internal and external problem is information system development, and then followed by innovative product development. Communication & visitation to Islamic micro finance institutions and socialization about micro takaful product to society are being less priority on this matter.DOI: 10.15408/etk.v16i2.5267

  7. PREFACE: Joint IPPP Durham/Cockcroft Institute/ICFA Workshop on Advanced QED methods for Future Accelerators

    Science.gov (United States)

    Bailey, I. R.; Barber, D. P.; Chattopadhyay, S.; Hartin, A.; Heinzl, T.; Hesselbach, S.; Moortgat-Pick, G. A.

    2009-11-01

    present in intense lasers - were also presented. Within the Furry picture the lowest order physics processes are represented by one vertex Feynman diagrams. Additionally, higher order processes in the Furry picture are thought to be important and are still not fully studied. The Advanced QED methods workshop also benefited greatly from reports on ongoing and planned experimental work on quantum processes in intense external fields. Some of the experiments reviewed were the NA43 and NA63 experiments using the inter atomic fields in aligned crystals at CERN. In the past, evidence has been obtained from successful experiments using an intense laser at the SLAC experiment E144. The possibility now exists for new experiments with intense laser light with the planned XFEL at DESY and the European Extreme Light Infrastructure. For upcoming accelerator projects, computer simulations of the first order processes in the Furry Picture during the bunch-bunch collision are being performed using the programs CAIN and Guinea-Pig++. The implementation of spin dynamics in these simulation programs was reported on at the workshop. This relatively small workshop generated a very productive intermix of theoretical, experimental and computational developments covering this important field of physics. Fruitful discussions took place covering improvements to the models, estimations of the remaining theoretical uncertainties and future updates to the existing simulations. It was felt that ongoing workshops in the same field would be of benefit to all those involved. The organisers would like to express their sincere thanks to all of the attendees for their contributions, to the staff of the Cockcroft Institute for hosting the workshop, to the IPPP at Durham for providing substantial funding and administrative support, and to ICFA for their sponsorship. We would also like to thank IOP Publishing for their assistance in publishing our proceedings in the Journal of Physics: Conference Series.

  8. The greening of higher education: A case study in three institutions in Medellin, Colombia

    International Nuclear Information System (INIS)

    Gomez, Catherine; Botero, Camilo M

    2012-01-01

    Incorporation of environmental variable (greening) in the daily routine of universities has taken force from the ends of the 20th century and nowadays its implementation in Colombia is a fact. This research project evaluated the grade of incorporation of such a variable in mission purposes of three higher education institutions in Medellin (Colombia). It included two different education levels (professional and technical) and used qualitative techniques (interviews to two teachers in each institution, one hour visits to two courses in each institution, and checklists for every visit as well as for the institutional analysis). In all the three study cases the environment is part of the institutional commitments, including their education, research, management processes, as well as activities with the society. This was reflected in the integration of greening in the curricula, the promotion of the research in environmental topics, the interdisciplinary cooperation and the adoption of internal policies. This work identifies some elements to develop the environmental education as a tool to comprehend the society and its environment as a whole; it constitutes a base for discussions, shows the advance of the three studied institutions, and discovers that shortcomings, that should be addressed, still exist.

  9. Transformational leadership in merging higher education institutions: A case study

    Directory of Open Access Journals (Sweden)

    Crispen Chipunza

    2010-06-01

    Research purpose: The objectives of this study were to establish an understanding of ‘transformational leadership’ and to determine the extent to which it was employed by leaders in an institution of higher education which had incorporated another institution. Motivations for the study: The study provides a starting point, not only for the successful implementation of higher education changes in the future but also the building of leadership commitment and alignment to the proposed changes in the sector as well as the development of institutional leadership teams to take responsibility for any other transformation processes. Research design, approach and method: The population of the study consisted of 350 full-time employees of the institution who had experienced the incorporation process. Two samples – one consisting of six executive management leaders and the other consisting of 153 employees – were used. Both qualitative and quantitative research approaches were employed using the case study method. Main findings: Results showed that transformational principles of idealised influence, intellectual stimulation, and inspirational motivation principles were used more than others and that employees were generally not satisfied with how the incorporation process had taken place. Practical/managerial implications: The results of the study affected the attitude and satisfaction of the employees in this study. Contribution/value-add: The study reveals that leaders in the institution played key roles such as shared vision, team work and the creation of an enabling environment. An important point that has emanated from this study is the evidence that during transformation, a lack of strategic direction and empowering of followers and capacitating them leads to dissatisfaction with the whole process, despite the transformation process being declared a success.

  10. Advancing the climate agenda: Exploiting material and institutional linkages to develop a menu of policy options

    NARCIS (Netherlands)

    van Asselt, H.D.; Gupta, J.; Biermann, F.

    2005-01-01

    The utilization of interlinkages of existing material and the strengthening and promotion of new institutional interlinkages can widen the climate change agenda through new and innovative policy and legal measures. Material linkages are inherent structural connections between policy domains that are

  11. 75 FR 7990 - Use of Community Development Loans by Community Financial Institutions To Secure Advances...

    Science.gov (United States)

    2010-02-23

    ... Fin. Brd. Res. No. 95-13 (Aug. 9, 1995). The purpose of the resolution was to prevent Banks from using..., because of amendments to the Bank Act, the specific issue which motivated the original resolution is no... Secure Advances; Secured Lending by Federal Home Loan Banks to Members and Their Affiliates; Transfer of...

  12. Influence of Institutional Experience and Technological Advances on Outcome of Stereotactic Body Radiation Therapy for Oligometastatic Lung Disease.

    Science.gov (United States)

    Rieber, Juliane; Abbassi-Senger, Nasrin; Adebahr, Sonja; Andratschke, Nicolaus; Blanck, Oliver; Duma, Marciana; Eble, Michael J; Ernst, Iris; Flentje, Michael; Gerum, Sabine; Hass, Peter; Henkenberens, Christoph; Hildebrandt, Guido; Imhoff, Detlef; Kahl, Henning; Klass, Nathalie Desirée; Krempien, Robert; Lohaus, Fabian; Lohr, Frank; Petersen, Cordula; Schrade, Elsge; Streblow, Jan; Uhlmann, Lorenz; Wittig, Andrea; Sterzing, Florian; Guckenberger, Matthias

    2017-07-01

    Many technological and methodical advances have made stereotactic body radiotherapy (SBRT) more accurate and more efficient during the last years. This study aims to investigate whether experience in SBRT and technological innovations also translated into improved local control (LC) and overall survival (OS). A database of 700 patients treated with SBRT for lung metastases in 20 German centers between 1997 and 2014 was used for analysis. It was the aim of this study to investigate the impact of fluorodeoxyglucose positron-emission tomography (FDG-PET) staging, biopsy confirmation, image guidance, immobilization, and dose calculation algorithm, as well as the influence of SBRT experience, on LC and OS. Median follow-up time was 14.3 months (range, 0-131.9 months), with 2-year LC and OS of 81.2% (95% confidence interval [CI] 75.8%-85.7%) and 54.4% (95% CI 50.2%-59.0%), respectively. In multivariate analysis, all treatment technologies except FDG-PET staging did not significantly influence outcome. Patients who received pre-SBRT FDG-PET staging showed superior 1- and 2-year OS of 82.7% (95% CI 77.4%-88.6%) and 64.8% (95% CI 57.5%-73.3%), compared with patients without FDG-PET staging resulting in 1- and 2-year OS rates of 72.8% (95% CI 67.4%-78.8%) and 52.6% (95% CI 46.0%-60.4%), respectively (P=.012). Experience with SBRT was identified as the main prognostic factor for LC: institutions with higher SBRT experience (patients treated with SBRT within the last 2 years of the inclusion period) showed superior LC compared with less-experienced centers (P≤.001). Experience with SBRT within the last 2 years was independent from known prognostic factors for LC. Investigated technological and methodical advancements other than FDG-PET staging before SBRT did not significantly improve outcome in SBRT for pulmonary metastases. In contrast, LC was superior with increasing SBRT experience of the individual center. Copyright © 2016 Elsevier Inc. All rights reserved.

  13. A study of institutional environment and household food security at ...

    African Journals Online (AJOL)

    The study looked into the current scenario of food security in Rwanda. After analysing the national level institutional and food security scenarios by using available secondary data, the researchers used primary data that have been collected from a random sample of 200 households spreading over six sectors of the Huye ...

  14. Which Is More Consequential: Fields of Study or Institutional Selectivity?

    Science.gov (United States)

    Ma, Yingyi; Savas, Gokhan

    2014-01-01

    The persisting gender pay gap favoring men among college graduates is a puzzle given women's remarkable success in postsecondary education. This article examines income disparities among recent college graduates by intersecting gender and social class and evaluating the relative importance of fields of study and institutional selectivity.…

  15. Leadership, Organizational, and Institutional Studies: Reconciling and Teaching Competing Perspectives

    Science.gov (United States)

    Shoup, John R.

    2016-01-01

    Leadership, organizational, and institutional theories provide competing explanations on the nature of leadership and role of leaders. Part of the problem is that each theory is often studied in isolation, leading to incomplete perspectives on the essence of leadership in value driven contexts. A holistic paradigm that blends the three dominant…

  16. Research Review of the Institute of African Studies: Contact

    African Journals Online (AJOL)

    Principal Contact. Prof. M.E. Kropp Dakubu Editor-in-Chief University of Ghana. Research Review. Institute of African Studies. P.O.Box LG73 Legon, Ghana. Phone: 211-24-4764006. Fax: 233-21-500512. Email: medakubu@ug.edu.gh. Support Contact. Dr Stephen Acheampong Phone: 211-24-4979233

  17. Indian Institutional Repositories: A Study of User's Perspective

    Science.gov (United States)

    Sawant, Sarika

    2012-01-01

    Purpose: The present study aims to investigate the experience, contribution and opinions of users of respective institutional repositories (IRs) developed in India. Design/methodology/approach: The survey method was used. The data collection tool was a web questionnaire, which was created with the help of software provided by surveymonkey.com…

  18. School of Ice: An Advanced Professional Development Program for Geoscience Faculty at Minority-Serving Institutions

    Science.gov (United States)

    Huffman, L. T.

    2017-12-01

    The School of Ice (SOI) program from the US Ice Drilling Program Office (IDPO) is designed for college faculty who teach at minority-serving institutions or historically black colleges and universities, but lessons learned transfer easily to any science course based on current research. The institute builds participants' background knowledge about ice core science and climate change while also providing experiences with activities and labs for transferring information to their students. After three years of highly successful workshops, our model has provided valuable lessons for creating powerful experiences for participants. This presentation will identify some of the key ideas including pairing researchers and educators as presenters; creating leadership teams capitalizing on partner strengths; building a science community willing to participate in education and outreach; and building participants' science content background knowledge and confidence while providing them with teaching models for transferring the knowledge to their students. Another important element is to demand teacher buy-in to ensure replication and dissemination. Also, IDPO's drilling technologies make it an ideal platform for intertwining engineering concepts and practices with science research to meet new science standards. In this session, we will share results of the institute evaluations including the impact on the educators as well as longitudinal analysis of data from interviews with past participants concerning continued impacts on their teaching, their courses and their students. Faculty who have attended this institute in the last three years have reported increases in their understanding of the content and how to teach it. They also report increased confidence in their ability to teach ice core science and climate change concepts. Elements of these successful workshops can inform both the development of college professional development and student courses, as well as the creation of

  19. Determining School Administrators’ Perceptions on Institutional Culture: A Qualitative Study

    Directory of Open Access Journals (Sweden)

    Secil Eda Kartal

    2016-03-01

    Full Text Available Schools, the where educational activities are carried out, are among the major institutions society considers as important. Schools undertake strategic responsibilities in maintaining cultural values and conveying them to future generations. The primary responsibility in achieving these missions is assigned to the school administrators. The purpose of this study is to determine the perceptions of school administrators on institutional culture. This is a qualitative study conducted on school administrators who were selected based on the volunteering principle. Perceptions of school administrators concerning their institutions’ culture and the differences between their institutional culture and other institution’s cultures were determined and analyzed. Findings of this study suggest that school administrators have both positive and negative opinions regarding their institutional culture and cultural difference. While love-respect, collaboration-solidarity and common history were prominent positive opinions; lack of communication, lack of shared values and low expectation were prominent negative opinions. In addition, participants stated the environment as a crucial factor when defining culture.

  20. Results of a comparison study of advanced reactors

    International Nuclear Information System (INIS)

    Bueno de Mesquita, K.G.; Gout, W.; Heil, J.A.; Tanke, R.H.J.; Geevers, F.

    1991-06-01

    The PINK programme is a 4-year programme of five parties involved in nuclear energy in the Netherlands: GKN (operator of the Dodewaard plant), KEMA (Research institute of the Netherlands Utilities), ECN (Netherlands Energy Research Foundation), NUCON (Engineering and Contracting Company) and IRI Interfaculty Reactor Institute of the Delft University of Technology), to coordinate their efforts to intensify the nuclear competence of the industry, the utilities and the research and engineering companies. This programme is sponsored by the Ministry of Economic Affairs. The PINK programme consists of five parts. This report pertains to part 1 of the programme: comparison study of advanced reactors concerning the four so-called second-stage designs SBWR, AP600, SIR and CANDU, which, compared to the first-stage reactor designs, features increased use of passive safety systems and simplification. The objective of the current study is to compare these advanced reactor designs in order to provide comprehensive information for the PINK steering committee that is useful in the selection process of a design for further study and development work. In ch. 2 the main features of the four reactors are highlighted. In ch. 3 the most important safety features and the behaviour of the four reactors under accident situations are compared. Passive safety systems are identified and forgivingness is described and compared. Results of the preliminary probabilistic safety analysis are presented. Ch. 4 deals with the proven technology of the four concepts, ch. 5 with the Netherlands requirements, ch. 6 with commercial aspects, and ch. 7 with the fuel cycle and radioactive waste produced. In ch. 8 the costs are compared and finally in ch. 9 conclusions are drawn and recommendations are made. (author). 13 figs

  1. Contributions of the National Institute of Nuclear Research to the advance of Science and Technology in Mexico. Commemorative edition 2010

    International Nuclear Information System (INIS)

    Duque M, G.; Jimenez R, M.; Monroy G, F.; Romero H, S.; Serment G, J.

    2010-01-01

    From the second decade of the X X century the applications of the nuclear energy have been important part of the scientific and technological patrimony in Mexico. Records exist with regard to the use of the radioisotopes and the radiations in our country in that time, and in a formal way until the year of 1950, in a process that culminates with the creation of the Comision Nacional de Energia Nuclear (CNEN. January 1, 1956). In January 12, 1972 were published the Organic Law that created to the Instituto Nacional de Energia Nuclear, being responsible for the works that the CNEN developed. The current Instituto Nacional de Investigaciones Nucleares (ININ) was constituted starting from the Regulation Law of the constitutional Article 27 in nuclear matter of January 26, 1979, abrogated and substituted by the Law in force of February 4, 1985. In this lapse they were undertaken multitude of projects with results and diverse achievements. From their creation, the mission of the ININ and the previous institutions has been to realize research in science and nuclear technology, to promote their peaceful uses and to diffuse the achieved advances, always searching for to link them to the economic, social, scientific and technological development of the country. In this occasion with the purpose of participating in the commemoration of the bicentennial of the independence and centennial of the Mexican revolution in our country, the ININ decided to publish this work, directed to a wide public, with the intention of providing a vision the most complete and appropriate possible of the activities in research and technology that it is carries out at the moment. This work also seeks to be a diffusion instrument of the tasks that they are carried out in the institute, in diverse subjects as: the basic research, the nuclear applications in the health, the agriculture and the industry, the studies on the contamination and the environment; the dosimetry; the radiological protection; as

  2. Advanced hybrid vehicle propulsion system study

    Science.gov (United States)

    Schwarz, R.

    1982-01-01

    Results are presented of a study of an advanced heat engine/electric automotive hybrid propulsion system. The system uses a rotary stratified charge engine and ac motor/controller in a parallel hybrid configuration. The three tasks of the study were (1) parametric studies involving five different vehicle types, (2) design trade-off studies to determine the influence of various vehicle and propulsion system paramaters on system performance fuel economy and cost, and (3) a conceptual design establishing feasibility at the selected approach. Energy consumption for the selected system was .034 1/km (61.3 mpg) for the heat engine and .221 kWh/km (.356 kWh/mi) for the electric power system over a modified J227 a schedule D driving cycle. Life cycle costs were 7.13 cents/km (11.5 cents/mi) at $2/gal gasoline and 7 cents/kWh electricity for 160,000 km (100,000 mi) life.

  3. Advances in soil-structure interaction studies

    International Nuclear Information System (INIS)

    Maheshwari, B.K.

    2011-01-01

    It is utmost important that lifeline infrastructures (such as bridges, hospitals, power plants, dams etc.) are safe and functional during earthquakes as damage or collapse of these structures may have far reaching implications. A lifeline's failure may hamper relief and rescue operations required just after an earthquake and secondly its indirect economical losses may be very severe. Therefore, safety of these structures during earthquakes is vital. Further, damage to nuclear facilities during earthquake may lead to disaster. These structures should be designed adequately taking into account all the important issues. Soil-Structure Interaction (SSI) is one of the design issues, which is often overlooked and even in some cases ignored. The effects of dynamic SSI are well understood and practiced in the nuclear power industry (for large foundations of the nuclear containment structures) since sixties. However, in last decade, there are many advances in techniques of SSI and those need to be incorporated in practice. Failures of many structures occurred during the 1989 Loma Prieta and 1994 Northridge, California earthquakes and the 1995 Kobe, Japan earthquake due to SSI or a related issue. Many jetties had failed in Andaman and Nicobar islands due to Sumatra earthquake and ensuing tsunamis. It is because of this recent experience that the importance of SSI on dynamic response of structures during earthquakes has been fully realized. General belief that the SSI effects are always beneficial for the structure is not correct. Some cases have been presented where it is shown that SSI effects are detrimental for the stability of the structure. This paper addresses the effects of dynamic SSI on the response of the structures and explains its importance. Further advances in SSI studies have been discussed

  4. Comparative inter-institutional study of stress among dentists.

    Science.gov (United States)

    Pozos-Radillo, Blanca E; Galván-Ramírez, Ma Luz; Pando, Manuel; Carrión, Ma De los Angeles; González, Guillermo J

    2010-01-01

    Dentistry is considered to be a stressful profession due to different factors caused by work, representing a threat to dentists'health. The objectives of this work were to identify and compare chronic stress in dentists among the different health institutions and the association of stress with risk factors. The study in question is observational, transversal and comparative; 256 dentists were included, distributed among five public health institutions in the city of Guadalajara, Jalisco, Mexico, namely: the Mexican Institute of Social Security (IMSS), the Ministry of Health (SS), the Integral Development of the Family (DIF), the Social Security Services Institute for the Workers (ISSSTE) and the University of Guadalajara (U. de G) Data were obtained by means of the census technique. Stress was identified using the Stress Symptoms Inventory and the statistical analysis was performed using the Odds Ratio (O.R.) and the chi-square statistic. From the total population studied, 219 subjects presented high levels of chronic stress and 37, low levels. In the results of comparative analysis, significant differences were found between IMSS and U. de G and likewise between IMSS and SS. However, in the analysis of association, only U. de G was found to be associated with the high level of chronic stress.

  5. Conceptual study of advanced PWR core design

    International Nuclear Information System (INIS)

    Kim, Young Jin; Chang, Moon Hee; Kim, Keung Ku; Joo, Hyung Kuk; Kim, Young Il; Noh, Jae Man; Hwang, Dae Hyun; Kim, Taek Kyum; Yoo, Yon Jong.

    1997-09-01

    The purpose of this project is for developing and verifying the core design concepts with enhanced safety and economy, and associated methodologies for core analyses. From the study of the sate-of-art of foreign advanced reactor cores, we developed core concepts such as soluble boron free, high convertible and enhanced safety core loaded semi-tight lattice hexagonal fuel assemblies. To analyze this hexagonal core, we have developed and verified some neutronic and T/H analysis methodologies. HELIOS code was adopted as the assembly code and HEXFEM code was developed for hexagonal core analysis. Based on experimental data in hexagonal lattices and the COBRA-IV-I code, we developed a thermal-hydraulic analysis code for hexagonal lattices. Using the core analysis code systems developed in this project, we designed a 600 MWe core and studied the feasibility of the core concepts. Two additional scopes were performed in this project : study on the operational strategies of soluble boron free core and conceptual design of large scale passive core. By using the axial BP zoning concept and suitable design of control rods, this project showed that it was possible to design a soluble boron free core in 600 MWe PWR. The results of large scale core design showed that passive concepts and daily load follow operation could be practiced. (author). 15 refs., 52 tabs., 101 figs

  6. Conceptual study of advanced PWR core design

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Young Jin; Chang, Moon Hee; Kim, Keung Ku; Joo, Hyung Kuk; Kim, Young Il; Noh, Jae Man; Hwang, Dae Hyun; Kim, Taek Kyum; Yoo, Yon Jong

    1997-09-01

    The purpose of this project is for developing and verifying the core design concepts with enhanced safety and economy, and associated methodologies for core analyses. From the study of the sate-of-art of foreign advanced reactor cores, we developed core concepts such as soluble boron free, high convertible and enhanced safety core loaded semi-tight lattice hexagonal fuel assemblies. To analyze this hexagonal core, we have developed and verified some neutronic and T/H analysis methodologies. HELIOS code was adopted as the assembly code and HEXFEM code was developed for hexagonal core analysis. Based on experimental data in hexagonal lattices and the COBRA-IV-I code, we developed a thermal-hydraulic analysis code for hexagonal lattices. Using the core analysis code systems developed in this project, we designed a 600 MWe core and studied the feasibility of the core concepts. Two additional scopes were performed in this project : study on the operational strategies of soluble boron free core and conceptual design of large scale passive core. By using the axial BP zoning concept and suitable design of control rods, this project showed that it was possible to design a soluble boron free core in 600 MWe PWR. The results of large scale core design showed that passive concepts and daily load follow operation could be practiced. (author). 15 refs., 52 tabs., 101 figs.

  7. The Critical Path Institute's approach to precompetitive sharing and advancing regulatory science.

    Science.gov (United States)

    Woosley, R L; Myers, R T; Goodsaid, F

    2010-05-01

    Many successful large industries, such as computer-chip manufacturers, the cable television industry, and high-definition television developers,(1) have established successful precompetitive collaborations focusing on standards, applied science, and technology that advance the field for all stakeholders and benefit the public.(2) The pharmaceutical industry, however, has a well-earned reputation for fierce competition and did not demonstrate willingness to share data or knowledge until the US Food and Drug Administration (FDA) launched the Critical Path Initiative in 2004 (ref. 3).

  8. Sorafenib-Regorafenib Sequential Therapy in Advanced Hepatocellular Carcinoma: A Single-Institute Experience.

    Science.gov (United States)

    Ueshima, Kazuomi; Nishida, Naoshi; Kudo, Masatoshi

    2017-01-01

    Previously, no therapeutic agent has been known to improve the overall survival compared with placebo in patients with hepatocellular carcinoma (HCC), who have progressed after sorafenib. In this patient population, regorafenib was first demonstrated to confer a survival benefit in the RESORCE trial, and subsequently it was approved as a second-line treatment for patients with advanced HCC. An open-label expanded access program (EAP) of regorafenib was implemented for compassionate use. We investigated the efficacy and safety of regorafenib based on our experience of the RESORCE trial and the EAP. Data from 5 patients from the RESORCE trial and 6 from the EAP were analyzed retrospectively. All patients had tolerated prior sorafenib and were progressing during sorafenib treatment. The median progression-free survival was 9.2 months (95% CI 2.3-16.1). One patient achieved a partial response and 7 achieved stable disease. The objective response rate was 9.1%, and the disease control rate was 72.7%. No treatment-associated mortalities were observed. Grade 3 hypophosphatemia was observed in 2 patients, grade 2 anorexia was observed in 5 patients, and grade 3 neutropenia was observed in 2 patients. Grade 2 and grade 3 thrombocytopenia were observed in 2 and 3 patients, respectively. All treatment-related adverse events were improved by reduction or interruption of regorafenib. Five patients showed decreased serum albumin levels. Sorafenib and regorafenib sequential therapy presents a safe and effective treatment option for patients with advanced HCC. © 2017 S. Karger AG, Basel.

  9. Advanced supersonic propulsion study, phase 3

    Science.gov (United States)

    Howlett, R. A.; Johnson, J.; Sabatella, J.; Sewall, T.

    1976-01-01

    The variable stream control engine is determined to be the most promising propulsion system concept for advanced supersonic cruise aircraft. This concept uses variable geometry components and a unique throttle schedule for independent control of two flow streams to provide low jet noise at takeoff and high performance at both subsonic and supersonic cruise. The advanced technology offers a 25% improvement in airplane range and an 8 decibel reduction in takeoff noise, relative to first generation supersonic turbojet engines.

  10. Conceptual study on advanced PWR system

    Energy Technology Data Exchange (ETDEWEB)

    Bae, Yoon Young; Chang, M H; Yu, K J; Lee, D J; Cho, B H; Kim, H Y; Yoon, J H; Lee, Y J; Kim, J P; Park, C T; Seo, J K; Kang, H S; Kim, J I; Kim, Y W; Kim, Y H

    1997-07-01

    In this study, the adoptable essential technologies and reference design concept of the advanced reactor were developed and related basic experiments were performed. (1) Once-through Helical Steam Generator: a performance analysis computer code for heli-coiled steam generator was developed for thermal sizing of steam generator and determination of thermal-hydraulic parameters. (2) Self-pressurizing pressurizer : a performance analysis computer code for cold pressurizer was developed. (3) Control rod drive mechanism for fine control : type and function were surveyed. (4) CHF in passive PWR condition : development of the prediction model bundle CHF by introducing the correction factor from the data base. (5) Passive cooling concepts for concrete containment systems: development of the PCCS heat transfer coefficient. (6) Steam injector concepts: analysis and experiment were conducted. (7) Fluidic diode concepts : analysis and experiment were conducted. (8) Wet thermal insulator : tests for thin steel layers and assessment of materials. (9) Passive residual heat removal system : a performance analysis computer code for PRHRS was developed and the conformance to EPRI requirement was checked. (author). 18 refs., 55 tabs., 137 figs.

  11. [Advances in the study of the nucleolus].

    Science.gov (United States)

    Feng, Jin-Mei; Sun, Jun; Wen, Jian-Fan

    2012-12-01

    As the most prominent sub-nuclear compartment in the interphase nucleus and the site of ribosome biogenesis, the nucleolus synthesizes and processes rRNA and also assembles ribosomal subunits. Though several lines of research in recent years have indicated that the nucleolus might have additional functions-such as the assembling of signal recognition particles, the processing of mRNA, tRNA and telomerase activities, and regulating the cell cycle-proteomic analyses of the nucleolus in three representative eukaryotic species has shown that a plethora of proteins either have no association with ribosome biogenesis or are of presently unknown function. This phenomenon further indicates that the composition and function of the nucleolus is far more complicated than previously thought. Meanwhile, the available nucleolar proteome databases has provided new approaches and led to remarkable progress in understanding the nucleolus. Here, we have summarized recent advances in the study of the nucleolus, including new discoveries of its structure, function, genomics/proteomics as well as its origin and evolution. Moreover, we highlight several of the important unresolved issues in this field.

  12. Conceptual study on advanced PWR system

    International Nuclear Information System (INIS)

    Bae, Yoon Young; Chang, M. H.; Yu, K. J.; Lee, D. J.; Cho, B. H.; Kim, H. Y.; Yoon, J. H.; Lee, Y. J.; Kim, J. P.; Park, C. T.; Seo, J. K.; Kang, H. S.; Kim, J. I.; Kim, Y. W.; Kim, Y. H.

    1997-07-01

    In this study, the adoptable essential technologies and reference design concept of the advanced reactor were developed and related basic experiments were performed. 1) Once-through Helical Steam Generator: a performance analysis computer code for heli-coiled steam generator was developed for thermal sizing of steam generator and determination of thermal-hydraulic parameters. 2) Self-pressurizing pressurizer : a performance analysis computer code for cold pressurizer was developed. 3) Control rod drive mechanism for fine control : type and function were surveyed. 4) CHF in passive PWR condition : development of the prediction model bundle CHF by introducing the correction factor from the data base. 5) Passive cooling concepts for concrete containment systems: development of the PCCS heat transfer coefficient. 6) Steam injector concepts: analysis and experiment were conducted. 7) Fluidic diode concepts : analysis and experiment were conducted. 8) Wet thermal insulator : tests for thin steel layers and assessment of materials. 9) Passive residual heat removal system : a performance analysis computer code for PRHRS was developed and the conformance to EPRI requirement was checked. (author). 18 refs., 55 tabs., 137 figs

  13. Impact Evaluation Study for Institution Strengthening of Social Food Distribution

    Directory of Open Access Journals (Sweden)

    Budiman Notoatmojo

    2016-03-01

    Full Text Available The general objectives of this study were to evaluate whether the implementation of activities for strengthening LDPM could achieve the expected goals, to evaluate whether the LDPM strengthening activities had a positive impact. The study analysis used was descriptive, comparison, and financial analysis. The results of this study have shown that LDPM farmers’ income have increased significantly, and the Gapoktan as LPDM farmers’ institution has been significantly developing as a Bulog function in procuring grain paddy from farmers during peak harvest and distributing rice to stabilize the price of rice during the limited rice in the market.

  14. Engineering Institute

    Science.gov (United States)

    Projects Past Projects Publications NSEC » Engineering Institute Engineering Institute Multidisciplinary engineering research that integrates advanced modeling and simulations, novel sensing systems and new home of Engineering Institute Contact Institute Director Charles Farrar (505) 665-0860 Email UCSD EI

  15. NATO Advanced Study Institute on Advances in the Computer Simulations of Liquid Crystals

    CERN Document Server

    Zannoni, Claudio

    2000-01-01

    Computer simulations provide an essential set of tools for understanding the macroscopic properties of liquid crystals and of their phase transitions in terms of molecular models. While simulations of liquid crystals are based on the same general Monte Carlo and molecular dynamics techniques as are used for other fluids, they present a number of specific problems and peculiarities connected to the intrinsic properties of these mesophases. The field of computer simulations of anisotropic fluids is interdisciplinary and is evolving very rapidly. The present volume covers a variety of techniques and model systems, from lattices to hard particle and Gay-Berne to atomistic, for thermotropics, lyotropics, and some biologically interesting liquid crystals. Contributions are written by an excellent panel of international lecturers and provides a timely account of the techniques and problems in the field.

  16. Predicting introductory programming performance: A multi-institutional multivariate study

    Science.gov (United States)

    Bergin, Susan; Reilly, Ronan

    2006-12-01

    A model for predicting student performance on introductory programming modules is presented. The model uses attributes identified in a study carried out at four third-level institutions in the Republic of Ireland. Four instruments were used to collect the data and over 25 attributes were examined. A data reduction technique was applied and a logistic regression model using 10-fold stratified cross validation was developed. The model used three attributes: Leaving Certificate Mathematics result (final mathematics examination at second level), number of hours playing computer games while taking the module and programming self-esteem. Prediction success was significant with 80% of students correctly classified. The model also works well on a per-institution level. A discussion on the implications of the model is provided and future work is outlined.

  17. 40 Anniversary of Institute of International Studies: From a Problem Laboratory to The Institute of International Studies

    Directory of Open Access Journals (Sweden)

    Alexander Leonidovich Chechevishnikov

    2016-01-01

    Full Text Available Applied foreign policy analysis is the hallmark of MGIMO-University. 2016 marks 40 anniversary of introduction of this element to the identity of our university in a form of Problem Research Laboratory. MGIMO development as a leading think tank took place in cooperation with the Ministry of Foreign Affairs and in close cooperation with other key institutions that shape foreign policy and are responsible for ensuring the national interests of Russia in the world. Today MGIMO's priority is the development of political policy expertise and analytical development-oriented scientific and practical support of the activities of state bodies. Such studies are the main but not the only focus of the Institute of International Studies.

  18. 40th Anniversary of Institute of International Studies: From a Problem Laboratory to The Institute of International Studies

    Directory of Open Access Journals (Sweden)

    Alexander Leonidovich Chechevishnikov

    2016-01-01

    Full Text Available Applied foreign policy analysis is the hallmark of MGIMO-University. 2016 marks 40th anniversary of introduction of this element to the identity of our university in a form of Problem Research Laboratory. MGIMO development as a leading think tank took place in cooperation with the Ministry of Foreign Affairs and in close cooperation with other key institutions that shape foreign policy and are responsible for ensuring the national interests of Russia in the world. Today MGIMO's priority is the development of political policy expertise and analytical development-oriented scientific and practical support of the activities of state bodies. Such studies are the main but not the only focus of the Institute of International Studies.

  19. Developing Institutional Capacity for Reproductive Health in Humanitarian Settings: A Descriptive Study.

    Directory of Open Access Journals (Sweden)

    Nguyen-Toan Tran

    Full Text Available Institutions play a central role in advancing the field of reproductive health in humanitarian settings (RHHS, yet little is known about organizational capacity to deliver RHHS and how this has developed over the past decade. This study aimed to document the current institutional experiences and capacities related to RHHS.Descriptive study using an online questionnaire tool.Respondents represented 82 institutions from 48 countries, of which two-thirds originated from low-and middle-income countries. RHHS work was found not to be restricted to humanitarian agencies (25%, but was also embraced by development organizations (25% and institutions with dual humanitarian and development mandates (50%. Agencies reported working with refugees (81%, internally-displaced (87% and stateless persons (20%, in camp-based settings (78%, and in urban (83% and rural settings (78%. Sixty-eight percent of represented institutions indicated having an RHHS-related policy, 79% an accountability mechanism including humanitarian work, and 90% formal partnerships with other institutions. Seventy-three percent reported routinely appointing RH focal points to ensure coordination of RHHS implementation. There was reported progress in RHHS-related disaster risk reduction (DRR, emergency management and coordination, delivery of the Minimum Initial Services Package (MISP for RH, comprehensive RH services in post-crisis/recovery situations, gender mainstreaming, and community-based programming. Other reported institutional areas of work included capacity development, program delivery, advocacy/policy work, followed by research and donor activities. Except for abortion-related services, respondents cited improved efforts in advocacy, capacity development and technical support in their institutions for RHHS to address clinical services, including maternal and newborn health, sexual violence prevention and response, HIV prevention, management of sexually-transmitted infections

  20. An exploratory study on awareness towards institutional social responsibility in Indian higher education institutions

    Directory of Open Access Journals (Sweden)

    Richa Mishra

    2016-06-01

    Full Text Available Institutional Social responsibility (ISR in context to a Higher Educational Institution has been defined as the ethical practice in transference of knowledge, and the active participation in betterment of quality of life in the society. It is an offshoot of the concept of Corporate Social responsibility (CSR, but unlike CSR, it is neither mandatory nor actively monitored or researched in Indian context. However, awareness towards aspects of ISR has been increasing, especially in Indian Universities. Indian Universities adopt practices related to Adoption of Villages, Awareness Drives, Environmental Care and rural Education initiatives. Critics often see ISR as an unnecessary burden; review of literature from around the world suggests that ISR practices contribute to increased accountability towards exploitation of resources by Educational Institutes as well as better reputation of Educational Institutes in the society. The purpose of this paper is to examine the perception towards the concept of ISR in Educational Institutes in India. The paper opted for a questionnaire-based exploratory survey of 50 faculty members, across Private Universities in Rajasthan. The findings suggest lacking awareness but a significant acceptance of need of ISR practices. The paper includes implications for the Universities to include ISR practices in their strategy to address its obligations to the society and simultaneously gain a competitive advantage.

  1. National Science and Technology Institute for Translational Medicine (INCT-TM): advancing the field of translational medicine and mental health.

    Science.gov (United States)

    Hallak, Jaime E C; Crippa, José Alexandre S; Quevedo, João; Roesler, Rafael; Schröder, Nadja; Nardi, Antonio Egidio; Kapczinski, Flávio

    2010-03-01

    Translational medicine has been described as the integrated application of innovative pharmacology tools, biomarkers, clinical methods, clinical technologies and study designs to improve the understanding of medical disorders. In medicine, translational research offers an opportunity for applying the findings obtained from basic research to every-day clinical applications. The National Science and Technology Institute for Translational Medicine is comprised of six member institutions (Universidade Federal do Rio Grande do Sul, Universidade de São Paulo-Ribeirão Preto, Universidade Federal do Rio de Janeiro, Pontifícia Universidade Católica do Rio Grande do Sul, Universidade Estadual de Santa Catarina and a core facility that serves all centers). The objectives of the project are divided into four areas: Institutional, Research, Human Resources and Technology for the Community and Productive Sector. In this manuscript, we describe some of the approaches used to attain the main objectives of the National Science and Technology Institute for Translational Medicine, which include the development of 1) animal models for bipolar disorder; 2) strategies to investigate neurobehavioral function and cognitive dysfunction associated with brain disorders; 3) experimental models of brain function and behavior, neuropsychiatric disorders, cell proliferation, and cancer; 4) Simulated Public Speaking and 5) Virtual reality simulation for inducing panic disorder and agoraphobia. The main focus of the National Science and Technology Institute for Translational Medicine is the development of more useful methods that allow for a better application of basic research-based knowledge to the medical field.

  2. Efficacy of doxorubicin after progression on carboplatin and paclitaxel in advanced or recurrent endometrial cancer: a retrospective analysis of patients treated at the Brazilian National Cancer Institute (INCA).

    Science.gov (United States)

    Moreira, Emeline; Paulino, Eduardo; Ingles Garces, Álvaro Henrique; Fontes Dias, Mariane S; Saramago, Marcos; de Moraes Lino da Silva, Flora; Thuler, Luiz Claudio Santos; de Melo, Andréia Cristina

    2018-01-31

    The treatment of endometrial cancer (EC) is challenging. There is no standard of care for patients who progressed after carboplatin and paclitaxel (CT) and all available drugs show a small response and poor long-term survival in this scenario. The objective of this study was to evaluate the efficacy and toxicity profile of palliative doxorubicin after progression to CT therapy in advanced or recurrent EC. A retrospective review of the Brazilian National Cancer Institute database between 2009 and 2013 was performed, and all patients with recurrent and advanced EC treated with palliative doxorubicin after progression on CT were included. Progression-free survival (PFS), overall survival (OS), objective response rates as well as toxicity were evaluated. A total of 33 patients were enrolled, with a median age of 65.7 years. Objective responses were documented in 12.1% (3.0% of complete responses and 9.1% of partial responses). The median PFS was 4.4 months, and the median OS was 8.1 months for patients exposed to doxorubicin. The most common adverse event was anemia observed in 60.6% of patients. This retrospective study suggests that doxorubicin has a modest activity in patients with advanced or recurrent EC after treatment with CT.

  3. Can the Institute of Medicine trump the dominant logic of nursing? Leading change in advanced practice education.

    Science.gov (United States)

    Dreher, Melanie C; Clinton, Patricia; Sperhac, Arlene

    2014-01-01

    The Institute of Medicine (IOM; 2010) has called for a transformation of the nursing profession to lead the redesign of health care in the United States. It acknowledges the need for profound change in nursing education, particularly advanced practice education, to produce the next generation of leaders in sufficient quantity to expand access, improve quality, and reduce cost. Although the IOM provides welcome validation of nursing's significant role, most of the recommendations are not new and have been advocated by nurse educators for decades. What has prevented us from creating the nimble and responsive educational programs that would ensure a sufficient corpus of advanced practice nurses with the relevant knowledge and skill to transform our ailing health system? Conceptualizing nursing as a complex, adaptive system (J.W. Begun and K. White, 1997), this article explores three examples of the dominant logic, grounded in a historical legacy that has kept the nursing profession from realizing its promise as a potent force: (a) the continuing preference for experience over education, (b) the belief that only nurses can teach nurses, and (c) the hegemony of the research doctorate. © 2014.

  4. Higher complication risk of totally implantable venous access port systems in patients with advanced cancer - a single institution retrospective analysis.

    Science.gov (United States)

    Chang, Yi-Fang; Lo, An-Chi; Tsai, Chung-Hsin; Lee, Pei-Yi; Sun, Shen; Chang, Te-Hsin; Chen, Chien-Chuan; Chang, Yuan-Shin; Chen, Jen-Ruei

    2013-02-01

    Totally implantable port systems are generally recommended for prolonged central venous access in diverse settings, but their risk of complications remains unclear for patients with advanced cancer. The aim of this study was to assess the risk of port system failure in patients with advanced cancer. We conducted a retrospective cohort study in a comprehensive cancer centre. A detailed chart review was conducted among 566 patients with 573 ports inserted during January-June, 2009 (average 345.3 catheter-days). Cox regression analysis was applied to evaluate factors during insertion and early maintenance that could lead to premature removal of the port systems due to infection or occlusion. Port system-related infection was significantly associated with receiving palliative care immediately after implantation (hazard ratio, HR = 7.3, 95% confidence interval, 95% CI = 1.2-46.0), after adjusting for probable confounders. Primary cancer site also impacted the occurrence of device-related infection. Receiving oncologic/palliative care (HR = 3.0, P = 0.064), advanced cancer stage (HR = 6.5, P = 0.077) and body surface area above 1.71 m(2) (HR = 3.4, P = 0.029) increased the risk of port system occlusion. Our study indicates that totally implantable port systems yield a higher risk of complications in terminally ill patients. Further investigation should be carefully conducted to compare outcomes of various central venous access devices in patients with advanced cancer and to develop preventive strategies against catheter failure.

  5. Improving Quality: How Leaders Advance Student Engagement at Private, Tuition-Driven Institutions

    Science.gov (United States)

    Sluis, Kimberly A.

    2017-01-01

    Students and families, lawmakers, and the general public have become increasingly concerned about the quality of U.S. higher education. Given the competitive higher education landscape, private, tuition-driven colleges and universities are particularly vulnerable to concerns about quality. This study investigates how faculty and administrative…

  6. TTI Phase 2 Institutional Support: Institute of Policy Studies of Sri ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    For IPS, this project will help enhance its research quality, organizational performance, and policy engagement. Enhancing research ... -consolidate the institutional transformations made to achieve improved performance ... -influence policies based on its work to place Sri Lanka on a smarter growth path -have an impact on ...

  7. Advanced nuclear systems. Review study; Fortgeschrittene Nuklearsysteme. Review Study

    Energy Technology Data Exchange (ETDEWEB)

    Liebert, Wolfgang; Glaser, Alexander; Pistner, Christoph [Interdisziplinaere Arbeitsgruppe Naturwissenschaft, Technik und Sicherheit (IANUS), Darmstadt University of Technology, Hochschulstrasse 10, D-64289 Darmstadt (Germany); Baehr, Roland; Hahn, Lothar [Institute for applied ecology (Oeko-Institut), Elisabethenstrasse 55-57, D-64283 Darmstadt (Germany)

    1999-04-01

    The task of this review study is to from provide an overview of the developments in the field of the various advanced nuclear systems, and to create the basis for more comprehensive studies of technology assessment. In an overview the concepts for advanced nuclear systems pursued worldwide are subdivided into eight subgroups. A coarse examination raster (set pattern) is developed to enable a detailed examination of the selected systems. In addition to a focus on enhanced safety features, further aspects are also taken into consideration, like the lowering of the proliferation risk, the enhancement of the economic competitiveness of the facilities and new usage possibilities (for instance concerning the relaxation of the waste disposal problem or the usage of alternative fuels to uranium). The question about the expected time span for realization and the discussion about the obstacles on the way to a commercially usable reactor also play a substantial role as well as disposal requirements as far as they can be presently recognized. In the central chapter of this study, the documentation of the representatively selected concepts is evaluated as well as existing technology assessment studies and expert opinions. In a few cases where this appears to be necessary, according technical literature, further policy advisory reports, expert statements as well as other relevant sources are taken into account. Contradictions, different assessments and dissents in the literature as well as a few unsettled questions are thus indicated. The potential of advanced nuclear systems with respect to economical and societal as well as environmental objectives cannot exclusively be measured by the corresponding intrinsic or in comparison remarkable technical improvements. The acceptability of novel or improved systems in nuclear technology will have to be judged by their convincing solutions for the crucial questions of safety, nuclear waste and risk of proliferation of nuclear weapons

  8. Regional hyperthermia combined with radiotherapy for locally advanced non-small cell lung cancers. A multi-institutional prospective randomized trial of the International Atomic Energy Agency

    International Nuclear Information System (INIS)

    Mitsumori, Michihide; Hiraoka, Masahiro; Zeng Zhifan; Oliynychenko, P.; Park, Jeong-Ho; Choi, Ihl-Bohng; Tatsuzaki, Hideo; Tanaka, Yoshiaki

    2007-01-01

    An International Atomic Energy Agency (IAEA)-sponsored, multi-institutional prospective randomized trial was conducted to clarify whether the combination of hyperthermia and radiotherapy improves the local response rate of locally advanced non-small cell lung cancer (NSCLC) compared with that obtained by radiotherapy alone. Between October 1998 and April 2002, 80 patients with locally advanced NSCLC were randomized to receive either standard radiation therapy alone (RT) or radiation therapy combined with hyperthermia (RT+HT). The primary endpoint was the local response rate. The secondary endpoints were local progression-free survival and overall survival. The median follow-up period was 204 days for all patients and 450 days for surviving patients. There were no significant differences between the two arms with regard to local response rate (P=0.49) or overall survival rate (P=0.868). However, local progression-free survival was significantly better in the RT+HT arm (P=0.036). Toxicity was generally mild and no grade 3 late toxicity was observed in either arm. Although improvement of local progression-free survival was observed in the RT+HT arm, this prospective randomized study failed to show any substantial benefit from the addition of hyperthermia to radiotherapy in the treatment of locally advanced NSCLC. (author)

  9. Impurity studies in the advanced toroidal facility

    International Nuclear Information System (INIS)

    Isler, R.C.; Horton, L.D.; Crume, E.C.; Howe, H.C.; Voronov, G.S.

    1989-01-01

    Impurities have played an important role in the initial stages of operation of the Advanced Toroidal Facility. Cleanup practices have been adequate enough that plasmas heated by ECH only can be operated in a quasi-steady state; however, neutral beam injected plasmas always collapse to a low temperature. It is not clear whether impurity radiation is actually responsible for initiating the collapse, but at the time the stored energy reaches a maximum, there are indications of poloidal asymmetries in radiation from low ionization stages, such as observed in marfes, which could play a dominant role in the plasma evolution. 3 refs., 5 figs

  10. Yoga as palliation in women with advanced cancer: a pilot study.

    Science.gov (United States)

    Carr, Tracey; Quinlan, Elizabeth; Robertson, Susan; Duggleby, Wendy; Thomas, Roanne; Holtslander, Lorraine

    2016-03-01

    The purpose of this pilot study was to investigate the palliative potential of home-based yoga sessions provided to women with advanced cancer. Personalised 45-minute yoga sessions were offered to three women with advanced cancer by an experienced yoga teacher. Each woman took part in a one-to-one interview after the completion of the yoga programme and was asked to describe her experiences of the programme's impact. The personalised nature of the yoga sessions resulted in similar positive physical and psychosocial effects comparable to those demonstrated in other studies with cancer patients. Participants described physical, mental, and emotional benefits as well as the alleviation of illness impacts. The enhancement of mind-body and body-spirit connections were also noted. Personalised home-based yoga programmes for people with advanced cancer may produce similar benefits, including palliation, as those institutionally-based programmes for people with non-advanced cancer.

  11. NATO Advanced Summer Institute on the Physics of Ion-Ion and Electron-Ion Collisions

    CERN Document Server

    McGowan, J

    1983-01-01

    Some of the earliest civilizations regarded the universe as organized around four principles, the four "elements" earth. water, air, and fire. Fire, which was the source of light and as such possessed an immaterial quality related to the spiritual world. was clearly the most impressive of these elements, although its quanti­ tative importance could not have been properly discerned. M- ern science has changed the names, but macroscopic matter is still divided into four states. The solid, liquid, and gaseous states are ordinary states, but the fourth state of matter, the plasma state, has retained a somewhat extraordinary character. It is now recognized that most of the matter of the universe is in the ionized state. but on the earth. the plasma state is still the exception. Hence the importance and also the difficulty of investigations dealing with ionized matter, which have been greatly furthered by the development of thermonuclear fusion research. The study of matter in the ionized state comprises a large d...

  12. Does gender affect career satisfaction and advancement in gastroenterology? Results of an AGA institute-sponsored survey.

    Science.gov (United States)

    Gerson, Lauren B; Twomey, Kay; Hecht, Gail; Lee, Linda; McQuaid, Ken; Pizarro, Theresa T; Street, Sarah; Yoshida, Cynthia; Early, Dayna

    2007-04-01

    Women comprise 19% of the American Gastroenterological Association (AGA) membership. We performed a prospective study to determine whether female gastroenterologists were less likely to achieve career advancement and satisfaction. We administered an online survey to AGA members from 2004-2006. The survey contained questions regarding effects of gender on career advancement, satisfaction with career, promotional policies, and integration of family and career. A total of 457 individuals (response rate 9% after 2 major invitations) completed the survey, including 262 (57%) women (20% in private practice, 53% in academic careers, and 27% trainees) and 195 men (23% in private practice, 58% in academic careers, and 19% trainees). The male gastroenterologists were significantly older (P careers for significantly more years (P = .002). There were no significant differences with respect to marital status, number of children, or number of hours worked between the genders. Men were more likely to achieve the rank of full professor (P = .035), and significantly more women reported that gender affected their career advancement (47% vs 9%; P careers reported less satisfaction with their careers (P = .01) and perceived more difficulty in achieving promotion and tenure. Women were more likely to choose private practice careers because of part-time options (P = .025). Equal numbers of men and women in practice reported difficulty balancing work and family life. Significantly more female than male gastroenterologists perceive that gender has affected their career advancement. Female academic gastroenterologists reported less overall career satisfaction and promotion than male academic gastroenterologists.

  13. Skills Required for Nursing Career Advancement: A Qualitative Study

    OpenAIRE

    Sheikhi, Mohammad Reza; Fallahi-Khoshnab, Masoud; Mohammadi, Farahnaz; Oskouie, Fatemeh

    2016-01-01

    Background Nurses require certain skills for progression in their field. Identifying these skills can provide the context for nursing career advancement. Objectives This study aimed to identify the skills needed for nurses’ career advancement. Materials and Methods A qualitative approach using content analysis was adopted to study a purposive sample of eighteen nurses working in te...

  14. A Meta-Analysis of Advance-Organizer Studies.

    Science.gov (United States)

    Stone, Carol Leth

    Long term studies of advance organizers (AO) were analyzed with Glass's meta-analysis technique. AO's were defined as bridges from reader's previous knowledge to what is to be learned. The results were compared with predictions from Ausubel's model of assimilative learning. The results of the study indicated that advance organizers were associated…

  15. A case study of a Cuban government institution

    International Nuclear Information System (INIS)

    Nunez, A.L.

    2004-01-01

    The aim of this contribution is to present a case study on the partial implementation of a knowledge management system in an institution. In this case the knowledge management has been directed toward the best performance of the organization. This organization is a non- profit one and its functions are the promotion, support and supervision of issues related to science, technology and environment for the economic development of a region. This case study can be implemented at any institution, including institutions of nuclear or radiological profiles. Many nuclear and radiological facilities have as a purpose the promotion, support and supervision of the nuclear applications for the biggest economic development. And this should be oriented to the implementation of best practices. The main author designed the methodology employed. The attention was centered in the objectives to be achieved for an efficient organization and the competence that should be possessed, were also identified. This study was developed with an expert group. Directive personnel, the total of advisory of institution and some selected workers formed it. 12 members integrated the overall group. They pondered the incidence of each one of the competencies in the functional objectives of the organization. The approach of the beneficiaries to this issue was also considered. In a second place a study was carried out about the competencies possessed by all the workers of the organization, and according to this the convergence-divergence matrix was created. The utility indexes for the necessary competence and for the possessed competence were calculated, as well as the satisfaction ratio between them. This ratio identifies how were the necessary competencies satisfied by the possessed competencies. It was determined in the study that the key competencies of the organization are No. 1, 2, 35, 37, 38, 39, 40, 41, 42, 43, 44, 45, 48, 50, 52, 53, 54, 55, 56 and 58. In general there are no difficulties for a

  16. Multifractionation in radiotherapy. A study of 49 patients treated at the Institut Gustave-Roussy

    International Nuclear Information System (INIS)

    Eschwege, F.; Cosset, J.M.; Dutreix, J.; Wibault, P.

    1981-01-01

    At the Institute Gustave Roussy were started, in 1978, two pilot studies using five daily fractions. The first protocol included 26 patients with advanced head and neck squamous cell carcinomas. The tolerance of the skin was excellent; for the mucosa, the tolerance can be considered very satisfactory. A total regression of the tumor was observed in 6 cases. For 11 additional cases, the regression was scored at 80%. Unfortunately, most of the patients relapsed: the survival is 71% at 9 months, and 23% at 18 months. A second pilot protocol included 23 patients presenting with very advanced thoracic or abdominal tumors. The aim was to study the tolerance and the feasability of a multifractionated scheme for the treatment of very large volumes. The skin tolerance was excellent, the good digestive tolerance was a constant feature. The tumor regression has to be analyzed with great care, because of the heterogeneity of the histologies. From 19 ''evaluable'' cases, we observed 7 total regressions. Due to the selection of very advanced tumours in this serie, the results in regard of survival are disappointing. In conclusion, these two feasability studies brought interesting results concerning the tolerance of the skin and of the small bowel. The results in term of tumor regression and survival are a little disappointing, and it seems to us possible to obtain a better efficiency increasing either the daily or the total dose [fr

  17. Florida State University's Institute for Family Violence Studies.

    Science.gov (United States)

    Oehme, Karen

    2018-01-01

    This article outlines the role of the Institute for Family Violence Studies (IFVS) within the Florida State University College of Social Work in navigating issues intersecting social work and the law ( http://familyvio.csw.fsu.edu/ ). By developing comprehensive state and national trainings for unique populations and conducting interdisciplinary research, the IFVS promotes public policy that benefits healthy families and decreases family and intimate partner violence. The crucial role of staff and students, the IFVS's collaborative alliances, and funding sources are highlighted. Projects such as the Clearinghouse on Supervised Visitation, the National Prevention Toolkit on Officer-Involved Domestic Violence, Successful Co-Parenting After Divorce, and the LGBTQ Family Life Project are described. Plans for future projects, as well as other new avenues for research, are summarized.

  18. Advances in radiobiological studies using a microbeam

    International Nuclear Information System (INIS)

    Hei, Tom K.; Brenner, David J.; Geard, Charles R.; Ballas, Leslie K.

    2009-01-01

    Recent developments in microbeam technology have made drastic improvements in particle delivery, focusing, image processing and precision to allow for rapid advances in our knowledge in radiation biology. The unequivocal demonstration that targeted cytoplasmic irradiation results in mutations in the nuclei of hit cells and the presence of non-targeted effects, all made possible using a charged particle microbeam, results in a paradigm shift in our basic understanding of the target theory and other radiation-induced low dose effects. The demonstration of a bystander effect in 3D human tissue and whole organisms have shown the potential relevance of the non-targeted response in human health. The demonstration of delayed mutations in the progeny of bystander cells suggest that genomic instability induced following ionizing radiation exposure is not dependent on direct damage to cell nucleus. The identification of specific signaling pathways provides mechanistic insight on the nature of the bystander process. (author)

  19. NRC review of Electric Power Research Institute's Advanced Light Water Reactor Utility Requirements Document - Evolutionary plant designs, Chapter 1, Project No. 669

    International Nuclear Information System (INIS)

    1992-08-01

    The staff of the US Nuclear Regulatory Commission has prepared Volume 2 (Parts 1 and 2) of a safety evaluation report (SER), ''NRC Review of Electric Power Research Institute's Advanced Light Water Reactor Utility Requirements Document -- Evolutionary Plant Designs,'' to document the results of its review of the Electric Power Research Institute's ''Advanced Light Water Reactor Utility Requirements Document.'' This SER gives the results of the staff's review of Volume II of the Requirements Document for evolutionary plant designs, which consists of 13 chapters and contains utility design requirements for an evolutionary nuclear power plant (approximately 1300 megawatts-electric)

  20. NRC review of Electric Power Research Institute's Advanced Light Water Reactor Utility Requirements Document - Evolutionary plant designs, Chapters 2--13, Project No. 669

    International Nuclear Information System (INIS)

    1992-08-01

    The staff of the US Nuclear Regulatory Commission has prepared Volume 2 (Parts 1 and 2) of a safety evaluation report (SER), ''NRC Review of Electric Power Research Institute's Advanced Light Water Reactor Utility Requirements Document -- Evolutionary Plant Designs,'' to document the results of its review of the Electric Power Research Institute's ''Advanced Light Water Reactor Utility Requirements Document.'' This SER gives the results of the staff's review of Volume II of the Requirements Document for evolutionary plant designs, which consists of 13 chapters and contains utility design requirements for an evolutionary nuclear power plant (approximately 1300 megawatts-electric)

  1. Scholarly productivity and professional advancement of junior researchers receiving KL2, K23, or K08 awards at a large public research institution.

    Science.gov (United States)

    Amory, John K; Louden, Diana K N; McKinney, Christy; Rich, Joanne; Long-Genovese, Stacy; Disis, Mary L

    2017-04-01

    How the productivity and careers of KL2 scholars compare with scholars receiving individual K-awards is unknown. The productivity of KL2 scholars (n=21) at our institution was compared with that of K08 (n=34) and K23 (n=26) scholars. KL2 and K23 scholars had greater productivity than K08 scholars ( p =0.01). Professional advancement was similar among groups. At our institution, scholarly productivity and professional advancement did not differ by type of K-award.

  2. Legal and institutional tools to mitigate plastic pollution affecting marine species: Argentina as a case study

    International Nuclear Information System (INIS)

    González Carman, Victoria; Machain, Natalia; Campagna, Claudio

    2015-01-01

    Highlights: • Plastic pollution in Argentina harms vulnerable marine species of turtles and mammals. • One tool to advance their conservation is policy. • The legal and institutional framework pertinent to plastic pollution is explored. • Laws and agencies are in place, yet implementation and enforcement is deficient. • Interventions to mitigate plastic pollution and protect marine species are advanced. - Abstract: Plastics are the most common form of debris found along the Argentine coastline. The Río de la Plata estuarine area is a relevant case study to describe a situation where ample policy exists against a backdrop of plastics disposed by populated coastal areas, industries, and vessels; with resultant high impacts of plastic pollution on marine turtles and mammals. Policy and institutions are in place but the impact remains due to ineffective waste management, limited public education and awareness, and weaknesses in enforcement of regulations. This context is frequently repeated all over the world. We list possible interventions to increase the effectiveness of policy that require integrating efforts among governments, the private sector, non-governmental organizations and the inhabitants of coastal cities to reduce the amount of plastics reaching the Río de la Plata and protect threatened marine species. What has been identified for Argentina applies to the region and globally

  3. Establishment of an Institute for Fusion Studies. Technical progress report, November 1, 1994--October 31, 1995

    International Nuclear Information System (INIS)

    1995-07-01

    The Institute for Fusion Studies is a national center for theoretical fusion plasma physics research. Its purposes are to (1) conduct research on theoretical questions concerning the achievement of controlled fusion energy by means of magnetic confinement--including both fundamental problems of long-range significance, as well as shorter-term issues; (2) serve as a national and international center for information exchange by hosting exchange visits, conferences, and workshops; and (3) train students and postdoctoral research personnel for the fusion energy program and plasma physics research areas. During FY 1995, a number of significant scientific advances were achieved at the IFS, both in long-range fundamental problems as well as in near-term strategic issues, consistent with the Institute's mandate. Examples of these achievements include, for example, tokamak edge physics, analytical and computational studies of ion-temperature-gradient-driven turbulent transport, alpha-particle-excited toroidal Alfven eigenmode nonlinear behavior, sophisticated simulations for the Numerical Tokamak Project, and a variety of non-tokamak and non-fusion basic plasma physics applications. Many of these projects were done in collaboration with scientists from other institutions. Research discoveries are briefly described in this report

  4. Skills Required for Nursing Career Advancement: A Qualitative Study.

    Science.gov (United States)

    Sheikhi, Mohammad Reza; Fallahi-Khoshnab, Masoud; Mohammadi, Farahnaz; Oskouie, Fatemeh

    2016-06-01

    Nurses require certain skills for progression in their field. Identifying these skills can provide the context for nursing career advancement. This study aimed to identify the skills needed for nurses' career advancement. A qualitative approach using content analysis was adopted to study a purposive sample of eighteen nurses working in teaching hospitals affiliated with the Qazvin, Shahid Beheshti, and Iran Universities of Medical Sciences. The data were collected through semi-structured interviews, and analyzed using conventional content analysis. The three themes extracted from the data included interpersonal capabilities, competency for career success, and personal capacities. The results showed that acquiring a variety of skills is essential for career advancement. The findings showed that personal, interpersonal, and functional skills can facilitate nurses' career advancement. The effects of these skills on career advancement depend on a variety of conditions that require further studies.

  5. Skills Required for Nursing Career Advancement: A Qualitative Study

    Science.gov (United States)

    Sheikhi, Mohammad Reza; Fallahi-Khoshnab, Masoud; Mohammadi, Farahnaz; Oskouie, Fatemeh

    2016-01-01

    Background Nurses require certain skills for progression in their field. Identifying these skills can provide the context for nursing career advancement. Objectives This study aimed to identify the skills needed for nurses’ career advancement. Materials and Methods A qualitative approach using content analysis was adopted to study a purposive sample of eighteen nurses working in teaching hospitals affiliated with the Qazvin, Shahid Beheshti, and Iran Universities of Medical Sciences. The data were collected through semi-structured interviews, and analyzed using conventional content analysis. Results The three themes extracted from the data included interpersonal capabilities, competency for career success, and personal capacities. The results showed that acquiring a variety of skills is essential for career advancement. Conclusions The findings showed that personal, interpersonal, and functional skills can facilitate nurses’ career advancement. The effects of these skills on career advancement depend on a variety of conditions that require further studies. PMID:27556054

  6. Reactivity studies on the advanced neutron source

    International Nuclear Information System (INIS)

    Ryskamp, J.M.; Redmond, E.L. II; Fletcher, C.D.

    1990-01-01

    An Advanced Neutron Source (ANS) with a peak thermal neutron flux of about 8.5 x 10 19 m -2 s -1 is being designed for condensed matter physics, materials science, isotope production, and fundamental physics research. The ANS is a new reactor-based research facility being planned by Oak Ridge National Laboratory (ORNL) to meet the need for an intense steady-state source of neutrons. The design effort is currently in the conceptual phase. A reference reactor design has been selected in order to examine the safety, performance, and costs associated with this one design. The ANS Project has an established, documented safety philosophy, and safety-related design criteria are currently being established. The purpose of this paper is to present analyses of safety aspects of the reference reactor design that are related to core reactivity events. These analyses include control rod worth, shutdown rod worth, heavy water voiding, neutron beam tube flooding, light water ingress, and single fuel element criticality. Understanding these safety aspects will allow us to make design modifications that improve the reactor safety and achieve the safety related design criteria. 8 refs., 3 tabs

  7. Current Practices in Global/International Advanced Pharmacy Practice Experiences: Home/Host Country or Site/Institution Considerations.

    Science.gov (United States)

    Alsharif, Naser Z; Dakkuri, Adnan; Abrons, Jeanine P; Williams, Dennis; Ombengi, David N; Zheng, HaiAn; Al-Dahir, Sara; Tofade, Toyin; Gim, Suzanna; O'Connell, Mary Beth; Ratka, Anna; Dornblaser, Emily

    2016-04-25

    International outreach by schools and colleges of pharmacy is increasing. In this paper, we provide current practice guidelines to establish and maintain successful global/international advanced pharmacy practice experiences (G/I APPEs) with specific recommendations for home/host country and host site/institution. The paper is based on a literature review (2000-2014) in databases and Internet searches with specific keywords or terms. Educational documents such as syllabi and memoranda of understanding (MoUs) from pharmacy programs were also examined. In addition, a preliminary draft was developed and the findings and recommendations were reviewed in a 90-minute roundtable discussion at the 2014 American Association of Colleges of Pharmacy Annual Meeting. Recommendations for the host country include travel considerations (eg, passport, visa, air travel), safety, housing, transportation, travel alerts and warnings, health issues, and financial considerations. For the home country, considerations for establishment of G/I APPE site (eg, vetting process, MoU, site expectations) are described. The paper is a resource for development of new G/I APPEs and provides guidance for continuous quality improvement of partnerships focusing on G/I pharmacy education.

  8. INTERSTITIAL BRACHYTHERAPY USING TEMPLATE FOR LOCALLY ADVANCED GYNAECOLOGICAL MALIGNANCIES- REVISITING THE FORGOTTEN CLASSICAL ART- A SINGLE INSTITUTE EXPERIENCE

    Directory of Open Access Journals (Sweden)

    Chatharaju Swarna Kumari

    2017-10-01

    Full Text Available BACKGROUND Brachytherapy is an important therapeutic strategy for the treatment of locally advanced gynaecologic (GYN cancers despite evolution of different newer radiotherapy techniques like high-dose-rate and image-guided BT. Despite being used in the management of advanced gynaecological cancer, currently there is a scarcity of studies and data on interstitial BT in Indian context. This is a retrospective analysis on 71 patients with locally advanced gynaecological malignancies treated in the period of 2010 to 2016 to assess the local tumour control, survival, and complications with the template (Syed-Neblett guided interstitial technique. MATERIALS AND METHODS The patients with a median age of 51 years treated from July 2010 to May 2016 were retrospectively reviewed. This study included previously unirradiated 71 patients with advance stage of gynaecological malignancies, not suitable for intracavitary brachytherapy due to distorted anatomy or extensive disease stage. Histologically all patients had squamous cell carcinoma (cervix= 56, vault= 9, vagina= 6 and treated by whole pelvis external beam radiation therapy (EBRT up to a total dose of 50 Gy in 25 fractions. These patients were further treated by high-dose-rate interstitial brachytherapy using SyedNeblett dedicated vaginal plastic template. During treatment all these patients were re-optimised and a dose of 15-21 Gy was delivered in 3 fractions with a minimum gap of 6 hours between fractions using Varisource iX HDR unit. RESULTS Out of 71 patients 5 were lost to followup during study period and they were excluded from the final analysis. The average followup duration ranged between 6-71 months and median followup was 20 months. This study included parameters like local disease control, acute/late complications and distant metastasis. Out of 66 patients, local disease control was seen in 54 (81.81% patients, whereas local recurrence was observed in 12 patients (18.18%. Distant

  9. Outcomes in a Multi-institutional Cohort of Patients Treated With Intraoperative Radiation Therapy for Advanced or Recurrent Renal Cell Carcinoma

    Energy Technology Data Exchange (ETDEWEB)

    Paly, Jonathan J. [Department of Radiation Oncology, Massachusetts General Hospital, Boston, Massachusetts (United States); Hallemeier, Christopher L. [Department of Radiation Oncology, Mayo Clinic, Rochester, Minnesota (United States); Biggs, Peter J.; Niemierko, Andrzej [Department of Radiation Oncology, Massachusetts General Hospital, Boston, Massachusetts (United States); Roeder, Falk [Department of Radiation Oncology, University of Heidelberg, Heidelberg (Germany); Martínez-Monge, Rafael [Radiation Oncology Division, University of Navarre, Pamplona (Spain); Whitson, Jared [Department of Urology, University of California San Francisco, San Francisco, California (United States); Calvo, Felipe A. [Departamento de Oncología, Hospital General Universitario Gregorio Marañón, Madrid (Spain); Fastner, Gerd; Sedlmayer, Felix [Department of Radiotherapy and Radio-Oncology, Paracelsus Medical University Clinics, Salzburg (Austria); Wong, William W. [Department of Radiation Oncology, Mayo Clinic, Scottsdale, Arizona (United States); Ellis, Rodney J. [Department of Radiation Oncology, Seidman Cancer Center University Hospitals Case Medical Center, Cleveland, Ohio (United States); Haddock, Michael G.; Choo, Richard [Department of Radiation Oncology, Mayo Clinic, Rochester, Minnesota (United States); Shipley, William U.; Zietman, Anthony L. [Department of Radiation Oncology, Massachusetts General Hospital, Boston, Massachusetts (United States); Efstathiou, Jason A., E-mail: jefstathiou@partners.org [Department of Radiation Oncology, Massachusetts General Hospital, Boston, Massachusetts (United States)

    2014-03-01

    Purpose/Objective(s): This study aimed to analyze outcomes in a multi-institutional cohort of patients with advanced or recurrent renal cell carcinoma (RCC) who were treated with intraoperative radiation therapy (IORT). Methods and Materials: Between 1985 and 2010, 98 patients received IORT for advanced or locally recurrent RCC at 9 institutions. The median follow-up time for surviving patients was 3.5 years. Overall survival (OS), disease-specific survival (DSS), and disease-free survival (DFS) were estimated with the Kaplan-Meier method. Chained imputation accounted for missing data, and multivariate Cox hazards regression tested significance. Results: IORT was delivered during nephrectomy for advanced disease (28%) or during resection of locally recurrent RCC in the renal fossa (72%). Sixty-nine percent of the patients were male, and the median age was 58 years. At the time of primary resection, the T stages were as follows: 17% T1, 12% T2, 55% T3, and 16% T4. Eighty-seven percent of the patients had a visibly complete resection of tumor. Preoperative or postoperative external beam radiation therapy was administered to 27% and 35% of patients, respectively. The 5-year OS was 37% for advanced disease and 55% for locally recurrent disease. The respective 5-year DSS was 41% and 60%. The respective 5-year DFS was 39% and 52%. Initial nodal involvement (hazard ratio [HR] 2.9-3.6, P<.01), presence of sarcomatoid features (HR 3.7-6.9, P<.05), and higher IORT dose (HR 1.3, P<.001) were statistically significantly associated with decreased survival. Adjuvant systemic therapy was associated with decreased DSS (HR 2.4, P=.03). For locally recurrent tumors, positive margin status (HR 2.6, P=.01) was associated with decreased OS. Conclusions: We report the largest known cohort of patients with RCC managed by IORT and have identified several factors associated with survival. The outcomes for patients receiving IORT in the setting of local recurrence compare favorably to

  10. The Hazard of Graduation: Analysis of Three Multivariate Statistics Used to Study Multi-Institutional Attendance

    Science.gov (United States)

    Muehlberg, Jessica Marie

    2013-01-01

    Adelman (2006) observed that a large quantity of research on retention is "institution-specific or use institutional characteristics as independent variables" (p. 81). However, he observed that over 60% of the students he studied attended multiple institutions making the calculation of institutional effects highly problematic. He argued…

  11. Benchmarking Investments in Advancement: Results of the Inaugural CASE Advancement Investment Metrics Study (AIMS). CASE White Paper

    Science.gov (United States)

    Kroll, Juidith A.

    2012-01-01

    The inaugural Advancement Investment Metrics Study, or AIMS, benchmarked investments and staffing in each of the advancement disciplines (advancement services, alumni relations, communications and marketing, fundraising and advancement management) as well as the return on the investment in fundraising specifically. This white paper reports on the…

  12. CULTURAL STUDIES: INSTITUTIONAL CRISIS OR THE TIME OF STRATEGIC DECISIONS

    Directory of Open Access Journals (Sweden)

    Irina Ya. Murzina

    2015-01-01

    Full Text Available The aim of this investigation is to signify of the problems of cultural studies as a science and educational practice in a situation of modernization of education. The publication continues the discussion started at the alignment meeting of Heads of Cultural Studies Departments in Russia – «The science of culture and cultural education: time for strategic decisions». Methods. The author has applied the following methods: analysis of existing points of view; reflection of the essence of the cultural knowledge and perspectives of cultural development of cultural studies science in Russia. Results. The research outcomes show that cultural studies in modern Russia are experiencing institutional crisis: insufficient definiteness and awareness by experts and publicity due to places and roles of culturological disciplines in educational process, but also the methodological bases of activity of culturologists. Aspects of culturological formation are considered and prospects of its development are specified. It was proposed to continue the discussion started at the alignment meeting of Herzen State Pedagogical University of Russia, and it will give an option to discuss the solution ways of current recessionary situation more fundamentally and subjectively on territory-regional level. Scientific novelty. The approaches to understanding the culture as areas of scientific knowledge are methodized; the areas of cultural education in the conditions of modernization are summarized. Practical significance. The research implementations can be used while improving the theoretical-methodological component of cultural education, and extending the horizons for topical current research works in the field of cultural studies

  13. Treatment of Advanced Glaucoma Study: a multicentre randomised controlled trial comparing primary medical treatment with primary trabeculectomy for people with newly diagnosed advanced glaucoma-study protocol.

    Science.gov (United States)

    King, Anthony J; Fernie, Gordon; Azuara-Blanco, Augusto; Burr, Jennifer M; Garway-Heath, Ted; Sparrow, John M; Vale, Luke; Hudson, Jemma; MacLennan, Graeme; McDonald, Alison; Barton, Keith; Norrie, John

    2017-10-26

    Presentation with advanced glaucoma is the major risk factor for lifetime blindness. Effective intervention at diagnosis is expected to minimise risk of further visual loss in this group of patients. To compare clinical and cost-effectiveness of primary medical management compared with primary surgery for people presenting with advanced open-angle glaucoma (OAG). Design : A prospective, pragmatic multicentre randomised controlled trial (RCT). Twenty-seven UK hospital eye services. Four hundred and forty patients presenting with advanced OAG, according to the Hodapp-Parish-Anderson classification of visual field loss. Participants will be randomised to medical treatment or augmented trabeculectomy (1:1 allocation minimised by centre and presence of advanced disease in both eyes). The primary outcome is vision-related quality of life measured by the National Eye Institute-Visual Function Questionnaire-25 at 24 months. Secondary outcomes include generic EQ-5D-5L, Health Utility Index-3 and glaucoma-related health status (Glaucoma Utility Index), patient experience, visual field measured by mean deviation value, logarithm of the mean angle of resolution visual acuity, intraocular pressure, adverse events, standards for driving and eligibility for blind certification. Incremental cost per quality-adjusted life-year (QALY) based on EQ-5D-5L and glaucoma profile instrument will be estimated. The study will report the comparative effectiveness and cost-effectiveness of medical treatment against augmented trabeculectomy in patients presenting with advanced glaucoma in terms of patient-reported health and visual function, clinical outcomes and incremental cost per QALY at 2 years. Treatment of Advanced Glaucoma Study will be the first RCT reporting outcomes from the perspective of those with advanced glaucoma. ISRCTN56878850, Pre-results. © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2017. All rights reserved. No commercial

  14. What are the implications of the Institute of Medicine report "The future of nursing: leading change, advancing health" for school nursing practice?

    Science.gov (United States)

    Sheetz, Anne H

    2012-11-01

    In 2010, the Robert Wood Johnson Foundation Initiative at the Institute of Medicine issued a comprehensive report entitled, "The future of nursing: leading change, advancing health." The following is a synopsis of the report, including excerpts, recommendations, and a discussion of school nursing implications.

  15. Technological capabilities, institutions and firm productivity: a multilevel study

    Czech Academy of Sciences Publication Activity Database

    Goedhuys, M.; Srholec, Martin

    2015-01-01

    Roč. 27, č. 1 (2015), s. 122-139 ISSN 0957-8811 Institutional support: PRVOUK-P23 Keywords : productivity * innovation * technological capability Subject RIV: AH - Economics Impact factor: 0.720, year: 2015

  16. Understanding institutional stakeholders’ perspectives on multidrug-resistant bacterial organism at the end of life: a qualitative study

    Science.gov (United States)

    Heckel, Maria; Herbst, Franziska A; Adelhardt, Thomas; Tiedtke, Johanna M; Sturm, Alexander; Stiel, Stephanie; Ostgathe, Christoph

    2017-01-01

    Background Information lacks about institutional stakeholders’ perspectives on management approaches of multidrug-resistant bacterial organism in end-of-life situations. The term “institutional stakeholder” includes persons in leading positions with responsibility in hospitals’ multidrug-resistant bacterial organism management. They have great influence on how strategies on multidrug-resistant bacterial organism management approaches in institutions of the public health system are designed. This study targeted institutional stakeholders’ individual perspectives on multidrug-resistant bacterial organism colonization or infection and isolation measures at the end of life. Methods Between March and December 2014, institutional stakeholders of two study centers, a German palliative care unit and a geriatric ward, were queried in semistructured interviews. Interviews were audiotaped, transcribed verbatim, and analyzed qualitatively with the aid of the software MAXQDA for qualitative data analysis using principles of Grounded Theory. In addition, two external stakeholders were interviewed to enrich data. Results Key issues addressed by institutional stakeholders (N=18) were the relevance of multidrug-resistant bacterial organism in palliative and geriatric care, contradictions between hygiene principles and patients’ and family caregivers’ needs and divergence from standards, frame conditions, and reflections on standardization of multidrug-resistant bacterial organism end-of-life care procedures. Results show that institutional stakeholders face a dilemma between their responsibility in protecting third persons and ensuring patients’ quality of life. Until further empirical evidence establishes a clear multidrug-resistant bacterial organism management approach in end-of-life care, stakeholders suggest a case-based approach. Conclusion The institutional stakeholders’ perspectives and their suggestion of a case-based approach advance the development

  17. Understanding institutional stakeholders' perspectives on multidrug-resistant bacterial organism at the end of life: a qualitative study.

    Science.gov (United States)

    Heckel, Maria; Herbst, Franziska A; Adelhardt, Thomas; Tiedtke, Johanna M; Sturm, Alexander; Stiel, Stephanie; Ostgathe, Christoph

    2017-01-01

    Information lacks about institutional stakeholders' perspectives on management approaches of multidrug-resistant bacterial organism in end-of-life situations. The term "institutional stakeholder" includes persons in leading positions with responsibility in hospitals' multidrug-resistant bacterial organism management. They have great influence on how strategies on multidrug-resistant bacterial organism management approaches in institutions of the public health system are designed. This study targeted institutional stakeholders' individual perspectives on multidrug-resistant bacterial organism colonization or infection and isolation measures at the end of life. Between March and December 2014, institutional stakeholders of two study centers, a German palliative care unit and a geriatric ward, were queried in semistructured interviews. Interviews were audiotaped, transcribed verbatim, and analyzed qualitatively with the aid of the software MAXQDA for qualitative data analysis using principles of Grounded Theory. In addition, two external stakeholders were interviewed to enrich data. Key issues addressed by institutional stakeholders (N=18) were the relevance of multidrug-resistant bacterial organism in palliative and geriatric care, contradictions between hygiene principles and patients' and family caregivers' needs and divergence from standards, frame conditions, and reflections on standardization of multidrug-resistant bacterial organism end-of-life care procedures. Results show that institutional stakeholders face a dilemma between their responsibility in protecting third persons and ensuring patients' quality of life. Until further empirical evidence establishes a clear multidrug-resistant bacterial organism management approach in end-of-life care, stakeholders suggest a case-based approach. The institutional stakeholders' perspectives and their suggestion of a case-based approach advance the development process of a patient-, family-, staff-, and institutional

  18. Study on advanced structural design for commercialized fast breeder reactors

    International Nuclear Information System (INIS)

    Morishita, Masaki; Aoto, Kazumi; Kasahara, Naoto; Asayama, Tai

    2003-05-01

    Japan Nuclear Cycle Development Institute (JNC) and Japan Atomic Power Company (JAPC) launched joint research programs on structural design and three-dimensional seismic isolation technologies, as part of the supporting R and D activities for the feasibility studies on commercialized fast breeder reactor cycle systems. A research project by JAPC under the auspices of the Ministry of Economy, Trade, and Industry (METI) with technical support by JNC is included in this joint study. This report contains the results of the research on the structural design technology. The research scope was identified as (1) FDS (FBR Design Standard), (2) Standardization of new material, and (3) System Based Code for Integrity, and the results of this year's studies are summarized as follows. (1) FDS (FBR Design Standard). R and D policy of Phase II study considering to the newest needs demanded for structural design were clarified, and R and D items were settled concretely. As for failure criteria, preliminary ratcheting-fatigue tests were conducted with rational methods, and Negligible Creep curves that settle creep designing region rationally were expanded their applying condition. R and D policy and items of guideline for inelastic analysis were clarified, and analyzing methodologies were studied. Summering up exemplification of thermal load prediction methodologies were progressed. To predict thermal striping loads, advanced frequency response function of thermal stress, and fatigue evaluation methodology were studied. (2) Standardization of new material. As for candidate 12-chromium stainless steel (added tungsten, non-added tungsten), that is expected to improve strength of components of commercialized FR, short and medium-term material tests, and creep-fatigue tests at small strain range were conducted. As for above candidate steel, TIG (Tungsten Inert Gas) welding method was recommended. Requirements to standardize new materials and index to select new materials were studied

  19. Advanced MRI increases the diagnostic accuracy of recurrent glioblastoma: Single institution thresholds and validation of MR spectroscopy and diffusion weighted MR imaging

    Directory of Open Access Journals (Sweden)

    Tomas Kazda

    2016-01-01

    Full Text Available The accurate identification of glioblastoma progression remains an unmet clinical need. The aim of this prospective single-institutional study is to determine and validate thresholds for the main metabolite concentrations obtained by MR spectroscopy (MRS and the values of the apparent diffusion coefficient (ADC to enable distinguishing tumor recurrence from pseudoprogression. Thirty-nine patients after the standard treatment of a glioblastoma underwent advanced imaging by MRS and ADC at the time of suspected recurrence — median time to progression was 6.7 months. The highest significant sensitivity and specificity to call the glioblastoma recurrence was observed for the total choline (tCho to total N-acetylaspartate (tNAA concentration ratio with the threshold ≥1.3 (sensitivity 100.0% and specificity 94.7%. The ADCmean value higher than 1313 × 10−6 mm2/s was associated with the pseudoprogression (sensitivity 98.3%, specificity 100.0%. The combination of MRS focused on the tCho/tNAA concentration ratio and the ADCmean value represents imaging methods applicable to early non-invasive differentiation between a glioblastoma recurrence and a pseudoprogression. However, the institutional definition and validation of thresholds for differential diagnostics is needed for the elimination of setup errors before implementation of these multimodal imaging techniques into clinical practice, as well as into clinical trials.

  20. Demographic pattern of male breast cancer: an institutional based study

    International Nuclear Information System (INIS)

    Tanseem, S.; Khan, M.M.; Khan, M.M.K.

    2011-01-01

    Background: Male breast cancer incidence rises with age with peak in the sixth and seventh decade. It is one of the rare diseases and accounts for less than 1% of all malignancies worldwide. It is usually diagnosed in the late stage with poor prognosis. Objective: The purpose of this study was to know the demographic pattern and tumour characteristic of breast cancer in men reported at Institute of Radiotherapy and Nuclear Medicine (IRNUM), Peshawar. Methods: Retrospective data was collected from the (IRNUM), Peshawar for a period of three years (2006-2008). The evaluation was done from the histopathological reports of mastectomy and biopsy specimens. All male patients in the age group 26 -86 year with breast cancer were included in the study. The age of the patients and tumour characteristics recorded were size, grade, type, skin involvement and stage. Results: Total number of male patients with breast cancer were 31 (2.1%) out of the total patients with breast malignancy during the study period with the mean age of 58.3 years. Tumour size ranged from 2 to 12 Cm. with average of 3.6 Cm. Invasive ductal carcinoma was found in 87% , papillary carcinoma in 6.5%, each of malignant fibrous histocytoma and sarcoma in 3.2% cases. Maximum number of patients was of grade II (41%). Patients in whom stage of the disease was know n were 22 cases with 45.5% had stage III disease and 32% had stage IV disease. Skin involvement was found positive in 8 (25.8%). Conclusion: Due to poor health care system breast cancer is diagnosed in a late stage of the disease and prognosis is poor. (author)

  1. Social Support for Wives in Advanced Studies

    Directory of Open Access Journals (Sweden)

    Icha Kusumadewi

    2017-08-01

    Full Text Available This study aimed to analyze social support on the wife who studies the master. The approach employed in this study was qualitative phenomenological. Samples in this study as many as two respondents, female students master, career woman, and married. In addition, there were secondary informants that comes from the husband, classmates, and coworkers subject. There are 6 secondary informants this research. Data were collected used interviews and observation. Forms interviews used in this study are free guided interviews and using participant observation. The validity of the data in this study using triangulation of sources and methods. The study found that two subjects in the lead role as a wife, staff, and students were able to run third that role with the help of others. But despite the help of others, this study provides new findings that the success of subjects affected their spiritual support that makes the subject able to survive to make the subject is able to do their job

  2. A single institution study of radiation dose received from CT imaging: A comparison to Malaysian NDRL

    Science.gov (United States)

    Osman, N. D.; Shamsuri, S. B. M.; Tan, Y. W.; Razali, M. A. S. M.; Isa, S. M.

    2017-05-01

    Advancement of CT technology has led to an increase in CT scanning as it improves the diagnosis. However, it is important to assess health risk of patients associated with ionising radiation received from CT. This study evaluated current dose distributions at Advanced Medical and Dental Institute (AMDI), Malaysia and was used to establish Local Diagnostic Reference Level (LDRL). Dose indicators such as CT Dose Index (CTDIvol and CTDIw) and Dose-Length Product (DLP) were gathered for all routine CT examinations performed at the Imaging Unit, AMDI from January 2015 to June 2016. The first and third quartile values for each dose indicator were determined. A total of 364 CT studies were performed during that period with the highest number of cases being Thorax-Abdomen-Pelvis (TAP) study (57% of total study). The CTDIw ranged between 2.0 mGy to 23.4 mGy per procedure. DLP values were ranged between 94 mGy.cm to 1687 mGy.cm. The local dose data was compared with the national DRL to monitor the current CT practice at AMDI and LDRL will be established from the calculated third quartile values of dose distribution. From the results, some of the local dose values exceeded the Malaysian and further evaluation is important to ensure the dose optimisation for patients.

  3. A single institution study of radiation dose received from CT imaging: A comparison to Malaysian NDRL

    International Nuclear Information System (INIS)

    Osman, N D; Shamsuri, S B M; Razali, M A S M; Isa, S M; Tan, Y W

    2017-01-01

    Advancement of CT technology has led to an increase in CT scanning as it improves the diagnosis. However, it is important to assess health risk of patients associated with ionising radiation received from CT. This study evaluated current dose distributions at Advanced Medical and Dental Institute (AMDI), Malaysia and was used to establish Local Diagnostic Reference Level (LDRL). Dose indicators such as CT Dose Index (CTDI vol and CTDI w ) and Dose-Length Product (DLP) were gathered for all routine CT examinations performed at the Imaging Unit, AMDI from January 2015 to June 2016. The first and third quartile values for each dose indicator were determined. A total of 364 CT studies were performed during that period with the highest number of cases being Thorax-Abdomen-Pelvis (TAP) study (57% of total study). The CTDI w ranged between 2.0 mGy to 23.4 mGy per procedure. DLP values were ranged between 94 mGy.cm to 1687 mGy.cm. The local dose data was compared with the national DRL to monitor the current CT practice at AMDI and LDRL will be established from the calculated third quartile values of dose distribution. From the results, some of the local dose values exceeded the Malaysian and further evaluation is important to ensure the dose optimisation for patients. (paper)

  4. Collaborative Genomics Study Advances Precision Oncology

    Science.gov (United States)

    A collaborative study conducted by two Office of Cancer Genomics (OCG) initiatives highlights the importance of integrating structural and functional genomics programs to improve cancer therapies, and more specifically, contribute to precision oncology treatments for children.

  5. Advances in clinical study of curcumin.

    Science.gov (United States)

    Yang, Chunfen; Su, Xun; Liu, Anchang; Zhang, Lin; Yu, Aihua; Xi, Yanwei; Zhai, Guangxi

    2013-01-01

    Curcumin has been estimated as a potential agent for many diseases and attracted great attention owing to its various pharmacological activities, including anti-cancer, and anti-inflammatory. Now curcumin is being applied to a number of patients with breast cancer, rheumatoid arthritis, Alzheimer's disease, colorectal cancer, psoriatic, etc. Several clinical trials have stated that curcumin is safe enough and effective. The objective of this article was to summarize the clinical studies of curcumin, and give a reference for future studies.

  6. From institutional merger integration to institutional strategic transformation: A case study of the strategic management paradigm at Shanghai Library

    Institute of Scientific and Technical Information of China (English)

    CHEN Chao

    2010-01-01

    This article attempts to apply the strategic management theory to the subsequent shaping up of a readjusted strategic development policy for Shanghai Library after its merger with the Institute of Scientific and Technological Information of Shanghai (ISTIS) in 1995.It also tries to analyze and explicate such an empirical implementation of institutional reintegration process through strategic management at Shanghai Metropolitan Library.By doing so,it aims to present an objective case study of activities based on the strategic management paradigm at a major Chinese metropolitan public library.

  7. From institutional merger integration to institutional strategic transformation:A case study of the strategic management paradigm at Shanghai Library

    Institute of Scientific and Technical Information of China (English)

    CHEN; Chao

    2010-01-01

    This article attempts to apply the strategic management theory to the subsequent shaping up of a readjusted strategic development policy for Shanghai Library after its merger with the Institute of Scientific and Technological Information of Shanghai(ISTIS)in 1995.It also tries to analyze and explicate such an empirical implementation of institutional reintegration process through strategic management at Shanghai Metropolitan Library.By doing so,it aims to present an objective case study of activities based on the strategic management paradigm at a major Chinese metropolitan public library.

  8. People don't talk in institutional statements: A methodological case study of the Institutional Analysis and Development Framework

    Science.gov (United States)

    Cristy Watkins; Lynne M. Westphal

    2015-01-01

    In this paper, we describe our application of Ostrom et al.'s ADICO syntax, a grammatical tool based in the Institutional Analysis and Development framework, to a study of ecological restoration decision making in the Chicago Wilderness region. As this method has only been used to look at written policy and/or extractive natural resource management systems, our...

  9. Advanced Exploration Systems (AES) Logistics Reduction and Repurposing Project: Advanced Clothing Ground Study Final Report

    Science.gov (United States)

    Byrne, Vicky; Orndoff, Evelyne; Poritz, Darwin; Schlesinger, Thilini

    2013-01-01

    All human space missions require significant logistical mass and volume that will become an excessive burden for long duration missions beyond low Earth orbit. The goal of the Advanced Exploration Systems (AES) Logistics Reduction & Repurposing (LRR) project is to bring new ideas and technologies that will enable human presence in farther regions of space. The LRR project has five tasks: 1) Advanced Clothing System (ACS) to reduce clothing mass and volume, 2) Logistics to Living (L2L) to repurpose existing cargo, 3) Heat Melt Compactor (HMC) to reprocess materials in space, 4) Trash to Gas (TTG) to extract useful gases from trash, and 5) Systems Engineering and Integration (SE&I) to integrate these logistical components. The current International Space Station (ISS) crew wardrobe has already evolved not only to reduce some of the logistical burden but also to address crew preference. The ACS task is to find ways to further reduce this logistical burden while examining human response to different types of clothes. The ACS task has been broken into a series of studies on length of wear of various garments: 1) three small studies conducted through other NASA projects (MMSEV, DSH, HI-SEAS) focusing on length of wear of garments treated with an antimicrobial finish; 2) a ground study, which is the subject of this report, addressing both length of wear and subject perception of various types of garments worn during aerobic exercise; and 3) an ISS study replicating the ground study, and including every day clothing to collect information on perception in reduced gravity in which humans experience physiological changes. The goal of the ground study is first to measure how long people can wear the same exercise garment, depending on the type of fabric and the presence of antimicrobial treatment, and second to learn why. Human factors considerations included in the study consist of the Institutional Review Board approval, test protocol and participants' training, and a web

  10. Increased risk of peripartum perinatal mortality in unplanned births outside an institution: a retrospective population-based study.

    Science.gov (United States)

    Engjom, Hilde M; Morken, Nils-Halvdan; Høydahl, Even; Norheim, Ole F; Klungsøyr, Kari

    2017-08-01

    Births in midwife-led institutions may reduce the frequency of medical interventions and provide cost-effective care, while larger institutions offer medically and technically advanced obstetric care. Unplanned births outside an institution and intrapartum stillbirths have frequently been excluded in previous studies on adverse outcomes by place of birth. The objective of the study was to assess peripartum mortality by place of birth and travel time to obstetric institutions, with the hypothesis that centralization reduces institution availability but improves mortality. This was a national population-based retrospective cohort study of all births in Norway from 1999 to 2009 (n = 648,555) using data from the Medical Birth Registry of Norway and Statistics Norway and including births from 22 gestational weeks or birthweight ≥500 g. Main exposures were travel time to the nearest obstetric institution and place of birth. The main clinical outcome was peripartum mortality, defined as death during birth or within 24 hours. Intrauterine fetal deaths prior to start of labor were excluded from the primary outcome. A total of 1586 peripartum deaths were identified (2.5 per 1000 births). Unplanned birth outside an institution had a 3 times higher mortality (8.4 per 1000) than institutional births (2.4 per 1000), relative risk, 3.5 (95% confidence interval, 2.5-4.9) and contributed 2% (95% confidence interval, 1.2-3.0%) of the peripartum mortality at the population level. The risk of unplanned birth outside an institution increased from 0.5% to 3.3% and 4.5% with travel time 2 hours, respectively. In obstetric institutions the mortality rate at term ranged from 0.7 per 1000 to 0.9 per 1000. Comparable mortality rates in different obstetric institutions indicated well-functioning routines for referral. Unplanned birth outside an institution was associated with increased peripartum mortality and with long travel time to obstetric institutions. Structural determinants have

  11. Advances in Epidemiological Studies of Herpes Zoster

    Directory of Open Access Journals (Sweden)

    Gu Xiaoming

    2015-12-01

    Full Text Available Mycoplasma genitalium (Mg commonly causes nongonococcal urethritis and cervicitis. Mg is a fastidious bacterium that poses difficulty in time-consuming isolation and culture. Lack of specificity for serological tests also hampers clinical research of Mg. With development of molecular biology, polymerase chain reaction tests, which exhibit high sensitivities and specificities, became primary tools for foundational and clinical studies of Mg.

  12. Advances in Epidemiological Studies of Herpes Zoster

    OpenAIRE

    Gu Xiaoming

    2015-01-01

    Mycoplasma genitalium (Mg) commonly causes nongonococcal urethritis and cervicitis. Mg is a fastidious bacterium that poses difficulty in time-consuming isolation and culture. Lack of specificity for serological tests also hampers clinical research of Mg. With development of molecular biology, polymerase chain reaction tests, which exhibit high sensitivities and specificities, became primary tools for foundational and clinical studies of Mg.

  13. Advanced supplier partnership practices: a case study.

    Science.gov (United States)

    Williams, B R

    2000-05-01

    This article describes how a supplier partnership was set up to avoid the typical purchasing relationship--price being inversely proportional to quantity and having the purchaser take all the risk of product obsolescence. The case study also describes how rate-based replenishment replaced time-based delivery, and how all these advantages were achieved at reduced administrative costs.

  14. Institute for Fusion Studies progress report, November 1, 1989--October 31, 1990

    International Nuclear Information System (INIS)

    Baldwin, D.E.

    1990-04-01

    During the past year significant progress was made in carrying out theoretical investigations pursuant to the scientific mission of the Institute. These achievements may be approximately classified in terms of the following research categories (often with considerable overlap); tokamak MHD studies, turbulence theory and plasma transport, computational plasma physics, stability theory, mathematical physics, advanced ideas, and space plasma physics-related problems. An overview of this work is contained in this report. This paper contains a list of the numerous scientific papers published in technical journals by IFS scientists during the past year. Also, detailed summaries of IFS Reports written during FY 90 are given in abstract form in Appendix A of this report. It is worth noting that, in addition to the many research publications, two lengthy review articles were written during the past year at the IFS: one on nonlinear drift waves and transport in magnetized plasmas, and the other an introduction to bifurcation theory

  15. System identification advances and case studies

    CERN Document Server

    Mehra, Raman K

    1976-01-01

    In this book, we study theoretical and practical aspects of computing methods for mathematical modelling of nonlinear systems. A number of computing techniques are considered, such as methods of operator approximation with any given accuracy; operator interpolation techniques including a non-Lagrange interpolation; methods of system representation subject to constraints associated with concepts of causality, memory and stationarity; methods of system representation with an accuracy that is the best within a given class of models; methods of covariance matrix estimation;methods for low-rank mat

  16. [Advances in studies on bear bile powder].

    Science.gov (United States)

    Zhou, Chao-fan; Gao, Guo-jian; Liu, Ying

    2015-04-01

    In this paper, a detailed analysis was made on relevant literatures about bear bile powder in terms of chemical component, pharmacological effect and clinical efficacy, indicating bear bile powder's significant pharmacological effects and clinical application in treating various diseases. Due to the complex composition, bear bile powder is relatively toxic. Therefore, efforts shall be made to study bear bile powder's pharmacological effects, clinical application, chemical composition and toxic side-effects, with the aim to provide a scientific basis for widespread reasonable clinical application of bear bile powder.

  17. Recent Advances in the Studies on Luotonins

    Directory of Open Access Journals (Sweden)

    Yurngdong Jahng

    2011-06-01

    Full Text Available Luotonins are alkaloids from the aerial parts of Peganum nigellastrum Bunge. that display three major skeleton types. Luotonins A, B, and E are pyrroloquinazolino-quinoline alkaloids, luotonins C and D are canthin-6-one alkaloids, and luotonin F is a 4(3H-quinazolinone alkaloid. All six luotonins have shown promising cytotoxicities towards selected human cancer cell lines, especially against leukemia P-388 cells. Luotonin A is the most active one, with its activity stemming from topoisomerase I-dependent DNA-cleavage. Such intriguing biological activities and unique structures have led not only to the development of synthetic methods for the efficient synthesis of these compounds, but also to interest in structural modifications for improving the biological properties. Recent progress in the study of luotonins is covered.

  18. Advanced Hydraulic Studies on Enhancing Particle Removal

    DEFF Research Database (Denmark)

    He, Cheng

    clarifier. The inlet zone of an existing rectangular storm water clarifier was redesigned to improve the fluid flow conditions and reduce the hydraulic head loss in order to remove the lamellar plates and adapt the clarifier to the needs of high-rate clarification of storm water with flocculant addition...... excessive local head losses and helped to select structural changes to reduce such losses. The analysis of the facility showed that with respect to hydraulic operation, the facility is a complex, highly non-linear hydraulic system. Within the existing constraints, a few structural changes examined......The removal of suspended solids and attached pollutants is one of the main treatment processes in wastewater treatment. This thesis presents studies on the hydraulic conditions of various particle removal facilities for possible ways to increase their treatment capacity and performance by utilizing...

  19. METHODS ADVANCEMENT FOR MILK ANALYSIS: THE MAMA STUDY

    Science.gov (United States)

    The Methods Advancement for Milk Analysis (MAMA) study was designed by US EPA and CDC investigators to provide data to support the technological and study design needs of the proposed National Children=s Study (NCS). The NCS is a multi-Agency-sponsored study, authorized under the...

  20. Chinese TEFL Academics' Perceptions about Research: An Institutional Case Study

    Science.gov (United States)

    Bai, Li; Millwater, Jan

    2011-01-01

    Research capacity building has become a prominent theme in higher education institutions in China, as across the world. However, Chinese TEFL (Teaching English as a Foreign Language) academics' research capacity has been quite limited. In order to build their research capacity, it is necessary to understand their perceptions about research. This…

  1. Nuclear structure studies at Saha Institute of Nuclear Physics using ...

    Indian Academy of Sciences (India)

    In-beam gamma-ray spectroscopy, carried out at the Saha Institute of Nuclear Physics in the recent past, using heavy-ion projectiles from the pelletron accelerator centres in the country and multi-detector arrays have yielded significant data on the structure of a large number of nuclei spanning different mass regions.

  2. Technological capabilities, institutions and firm productivity: a multilevel study

    Czech Academy of Sciences Publication Activity Database

    Goedhuys, M.; Srholec, Martin

    2015-01-01

    Roč. 27, č. 1 (2015), s. 122-139 ISSN 0957-8811 R&D Projects: GA ČR(CZ) GAP402/10/2310 Institutional support: RVO:67985998 Keywords : productivity * innovation * technological capability Subject RIV: AH - Economics Impact factor: 0.720, year: 2015

  3. ATF [Advanced Toroidal Facility]-2 studies

    International Nuclear Information System (INIS)

    Lyon, J.F.; Carreras, B.A.; Dominguez, N.

    1989-10-01

    Design studies for a low-aspect-ratio, large next-generation stellarator, ATF-II, with high-current-density, high-field, stable NbTi/Cu helical windings are described. The design parameters are an average plasma radius of 0.52 m, a major radius of 2 m, and a field on axis of 4-5 T, with 10 to 15 MW of heating power. Such a device would be comparable in scope to other next-generation stellarators but would have roughly the same aspect ratio as the tokamaks without, however, the need for current drive to sustain steady-state operation. A number of low-aspect-ratio physics issues need to be addressed in the design of ATF-II, primarily compromises between high-beta capability and good confinement properties. A six-field-period Compact Torsatron is chosen as a reference design for ATF-II, and its main features and performance predictions are discussed. An integrated (beta capability and confinement) optimization approach and optimization of superconducting windings are also discussed. 36 refs., 13 figs., 2 tabs

  4. Advanced studies in chemistry control with morpholine

    International Nuclear Information System (INIS)

    Riddle, J.M.

    1992-07-01

    Prior studies at Beaver Valley Unit 1 and at Prairie Island found that the substitution of morpholine for ammonia reduced corrosion and iron transport in the feedtrain of pressurized water reactors. The benefits of using morpholine encouraged other utilities to consider morpholine water chemistry. Calvert Cliffs Unit 1 was the first domestic PWR with deep-bed condensate polishers to use morpholine water chemistry. Typically a bed is operated in the hydrogen cycle for eight to ten days, followed by an additional 25 days in the morpholine cycle. Morpholine reduced feedwater iron levels by 28 percent. With morpholine treatment at Calvert Cliffs Unit 1, corrosion product transport in feedwater was reduced by a factor of 1.3 -- 1.4. Morpholine treatment at higher levels at Prairie Island Unit 2 provided a factor of 2.3 reduction in feedwater iron transport, in agreement with data from Electricity de France. EdF data show that the factor increases as the pH for ammonia chemistry is reduced from 9.5. When possible, the factors were compared at a pH of 9.2 for morpholine at room temperature. Aqueous solutions of morpholine thermally decompose at increasing rates with temperature above about 288 degree C (550 degree F). Oxygen and several metal oxides appear to increase the rate of decomposition to a small extent. Acetate, formate, and various amines, including ammonia, are the principal decomposition products

  5. Pediatric advance care planning from the perspective of health care professionals: a qualitative interview study.

    Science.gov (United States)

    Lotz, Julia D; Jox, Ralf J; Borasio, Gian Domenico; Führer, Monika

    2015-03-01

    Pediatric advance care planning differs from the adult setting in several aspects, including patients' diagnoses, minor age, and questionable capacity to consent. So far, research has largely neglected the professionals' perspective. We aimed to investigate the attitudes and needs of health care professionals with regard to pediatric advance care planning. This is a qualitative interview study with experts in pediatric end-of-life care. A qualitative content analysis was performed. We conducted 17 semi-structured interviews with health care professionals caring for severely ill children/adolescents, from different professions, care settings, and institutions. Perceived problems with pediatric advance care planning relate to professionals' discomfort and uncertainty regarding end-of-life decisions and advance directives. Conflicts may arise between physicians and non-medical care providers because both avoid taking responsibility for treatment limitations according to a minor's advance directive. Nevertheless, pediatric advance care planning is perceived as helpful by providing an action plan for everyone and ensuring that patient/parent wishes are respected. Important requirements for pediatric advance care planning were identified as follows: repeated discussions and shared decision-making with the family, a qualified facilitator who ensures continuity throughout the whole process, multi-professional conferences, as well as professional education on advance care planning. Despite a perceived need for pediatric advance care planning, several barriers to its implementation were identified. The results remain to be verified in a larger cohort of health care professionals. Future research should focus on developing and testing strategies for overcoming the existing barriers. © The Author(s) 2014.

  6. A Study on Performance Requirements for Advanced Alarm System

    International Nuclear Information System (INIS)

    Seong, Duk Hyun; Jeong, Jae Hoon; Sim, Young Rok; Ko, Jong Hyun; Kim, Jung Seon; Jang, Gwi Sook; Park, Geun Ok

    2005-01-01

    A design goals of advanced alarm system is providing advanced alarm information to operator in main control room. To achive this, we applied computer based system to Alarm System. Because, It should apply data management and advanced alarm processing(ie. Data Base Mangegment System and S/W module for alarm processing). These are not impossible in analog based alarm system. And, preexitance research examples are made on digital computer. We have digital systems for test of advanced alarm system table and have tested and studied using by test equipment in the view point of the system performance, stability and security. In this paper, we discribed about general software architecture of preexitance research examples. Also, CPU performance and requirements of system software that served to accommodate it, stability and security

  7. Reliability of diffusion-weighted imaging in acute ischemic stroke. A multi-institutional multivendor validation study

    International Nuclear Information System (INIS)

    Sasaki, Makoto; Yamada, Kei; Watanabe, Yoshiyuki; Matsui, Mieko; Ida, Masahiro

    2006-01-01

    Diffusion-weighted imaging (DWI) is widely applied for evaluating patients with acute ischemic stroke. However, its display conditions are different among institutions, and reliability of the apparent diffusion coefficient (ADC) has not been validated enough. Recently, we proposed an easy-to-use technique to standardize display conditions, in which window width and level are normalized by the signal intensity of brain tissue on b0 images. We carried out a multi-institutional multivendor study, and revealed that the technique successfully minimized difference in the display condition among institutions and vendors. On the other hand, we found that the ADC value is significantly different among vendors and static magnetic fields, suggesting that the ADC should be evaluated semiquantitatively. Standardization and technical advancement are considered to be necessary to improve reliability of DWI in acute stroke managements. (author)

  8. A STUDY ON INDIAN HIGHER EDUCATIONAL INSTITUTE BASED BUSINESS INCUBATORS

    OpenAIRE

    RANA BASU; DHRUBES BISWAS

    2013-01-01

    The purpose of this paper is to identify and explore the various range of business incubation services being provided to the nascent entrepreneurs which is based on comprehensive compilation and subsequent analysis of literature followed by case based approach in context to Indian higher educational institute (HEI) based business incubation centres. The objective behind this research is to critically assess the assistance services and to prioritize the service dimensions provided by the busin...

  9. Institutions and service employment: a panel study for OECD countries

    OpenAIRE

    Messina, Julián

    2004-01-01

    We live in a service economy, but the extent of development of service employment differs across developed countries. This paper assesses the role of structural factors and institutions in explaining the common patterns and main di?erences in the recent expansion of service employment in OECD countries. It finds that GDP per capita, the size of the government sector and the extent of urbanization are positively associated with the service employment share. However, the evidence suggests that ...

  10. Can internationalisation really lead to institutional competitive advantage? : a study of 16 Dutch public higher education institutions

    NARCIS (Netherlands)

    dr. Haijing de Haan

    2014-01-01

    Public higher education institutions (PHEIs) have widely acknowledged a positive relationship between internationalization and their institutional competitive advantage enhancement. Although some concerns have been raised by practitioners and researchers about whether institutional competitive

  11. Institutional initiatives in professional scientific ethics: three case studies

    Science.gov (United States)

    Nickless, Edmund; Bilham, Nic

    2015-04-01

    Learned and professional scientific bodies can play a vital role in promoting ethical behaviours, giving practical substance to theoretical consideration of geoethical principles and complementing the efforts of individual scientists and practitioners to behave in a professional and ethical manner. Institutions may do this through mandatory professional codes of conduct, by developing guidelines and initiatives to codify and stimulate the uptake of best practice, and through wider initiatives to engender a culture conducive to such behaviours. This presentation will outline three current institutional initiatives which directly or indirectly address scientific ethics: i. The UK Science Council's Declaration on Diversity, Equality and Inclusion. ii. Development and promulgation of the American Geosciences Institute's (AGI) Guidelines for Ethical Professional Conduct. iii. The American Geophysical Union's (AGU) Scientific Code of Conduct and Professional Ethics. The focus of the Science Council and its member bodies (including the Geological Society of London) on diversity is of central importance when considering ethical behaviours in science. First, improving equality and diversity in the science workforce is at the heart of ethical practice, as well as being essential to meeting current and future skills needs. Second, in addition to demographic diversity (whether in terms of gender, race, economic status, sexuality or gender identity, etc), an important dimension of diversity in science is to allow space for a plurality of scientific views, and to nurture dissenting voices - essential both to the development of scientific knowledge and to its effective communication to non-technical audiences.

  12. A STUDY OF LOCALLY ADVANCED CARCINOMA OF BREAST

    Directory of Open Access Journals (Sweden)

    Prabhakar Jenna

    2017-08-01

    Full Text Available BACKGROUND Worldwide, breast cancer is the most frequent cancer in women and represents the second leading cause of cancer death among women. Locally advanced breast cancer constitutes more than 50-70% of the patients presenting for treatment has two common problems in treatment. Achieving local control and prolonging survival by preventing or delaying distant metastasis. Today, treatment of LABC requires a combination of systemic and local/regional therapies. The aim of the study is to study the clinicopathological presentation, age distribution and various modes of management of locally advanced breast carcinoma. Worldwide breast cancer is the most frequent cancer in women and represents the second leading cause of cancer death among women. Locally advanced breast cancer constitutes more than 50-70% of the patients presenting treatment. MATERIALS AND METHODS The present study includes 50 patients who attended Department of General Surgery for a period of three years. RESULTS The patients were regularly followed up and at the end of the study 35 (70% of the patients were doing well. 4(8% of the patients developed distant metastasis and 3 (6% of the patients developing local recurrence. 8 (16% of the patients were lost follow up. CONCLUSION About half of the cases presenting with breast cancer are in locally advanced stages. Multimodality therapy is the effective treatment of locally advanced carcinoma of breast. Breast cancer management is a challenge and improvement in therapies are needed for disease-free interval and overall survival period.

  13. Faculty Study: New Mexico Higher Education Institutions Compared with Regional Peers. Gap Analysis

    Science.gov (United States)

    McClure, Beverlee J.

    2006-01-01

    This study addresses concerns regarding compensation disparities between New Mexico institutions and their peers. A recommended adjustment schedule with fiscal requirements is included, but not specific recommendations for faculty at individual institutions. The average salaries for New Mexico institutions were compared with regional peers to…

  14. Annual report of the Institute for Nuclear Study, University of Tokyo, 1981

    International Nuclear Information System (INIS)

    1982-01-01

    In this annual report, the research activities and technical developments carried out in the Institute for Nuclear Study during the period from January to December, 1981, are reviewed. Four research divisions are active at present, namely Low Energy Physics, High Energy Physics, Theoretical Physics and the Study Group of High Energy, Heavy Ion Project. The research facilities in the INS are open to all researchers in Japan. In the Low Energy Physics Division, the studies on nuclear structures and nuclear reactions were continued with the SF cyclotron. In the High Energy Physics Division, the studies on photo-reaction were continued with the 1.3 GeV electron synchrotron. The Theoretical Physics Division sponsored various workshops, developed computer programs and promoted collaboration among physicists as a research center of theoretical nuclear and particle physics besides its own activities. The Study Group of High Energy, Heavy Ion Project redesigned the whole accelerator complex, and the studies on heavy ion beam accumulation were advanced, using the accumulator ring ''TARN''. The studies on high energy, heavy ion collision were continued at the Bevalac facility. (Kako, I.)

  15. Advanced stratified charge rotary aircraft engine design study

    Science.gov (United States)

    Badgley, P.; Berkowitz, M.; Jones, C.; Myers, D.; Norwood, E.; Pratt, W. B.; Ellis, D. R.; Huggins, G.; Mueller, A.; Hembrey, J. H.

    1982-01-01

    A technology base of new developments which offered potential benefits to a general aviation engine was compiled and ranked. Using design approaches selected from the ranked list, conceptual design studies were performed of an advanced and a highly advanced engine sized to provide 186/250 shaft Kw/HP under cruise conditions at 7620/25,000 m/ft altitude. These are turbocharged, direct-injected stratified charge engines intended for commercial introduction in the early 1990's. The engine descriptive data includes tables, curves, and drawings depicting configuration, performance, weights and sizes, heat rejection, ignition and fuel injection system descriptions, maintenance requirements, and scaling data for varying power. An engine-airframe integration study of the resulting engines in advanced airframes was performed on a comparative basis with current production type engines. The results show airplane performance, costs, noise & installation factors. The rotary-engined airplanes display substantial improvements over the baseline, including 30 to 35% lower fuel usage.

  16. Development of a conceptual policy framework for advanced practice nursing: an ethnographic study.

    Science.gov (United States)

    Schober, Madrean M; Gerrish, Kate; McDonnell, Ann

    2016-06-01

    To report on a study examining policy development for advanced practice nursing from intent of policy to realization in practice. Inclusion of advanced practice nursing roles in the healthcare workforce is a worldwide trend. Optimal advanced nursing practice requires supportive policies. Little is known about how policy is developed and implemented. Ethnography using an instrumental case study approach was selected to give an in-depth understanding of the experiences of one country (Singapore) to contribute to insight into development elsewhere. The four-phase study was conducted from 2008-2012 and included document analysis (n = 47), interviews with key policy decision makers (n = 12), interviews with nursing managers and medical directors (n = 11), interviews and participant observation with advanced practice nurses (n = 15). Key policymakers in positions of authority were able to promote policy development. However, this was characterized by lack of strategic planning for implementation. A vague understanding by nursing managers and medical directors of policies, the role and its position in the healthcare workforce led to indecision and uncertainty in execution. Advanced practice nurses developed their role based on theory acquired in their academic programme but were unsure what role to assume in practice. Lack of clear guidelines led to unanticipated difficulties for institutions and healthcare systems. Strategic planning could facilitate integration of advanced practice nurses into the healthcare workforce. A Conceptual Policy Framework is proposed as a guide for a coordinated approach to policy development and implementation for advanced practice nursing. © 2016 John Wiley & Sons Ltd.

  17. Energy Efficient Engine program advanced turbofan nacelle definition study

    Science.gov (United States)

    Howe, David C.; Wynosky, T. A.

    1985-01-01

    Advanced, low drag, nacelle configurations were defined for some of the more promising propulsion systems identified in the earlier Benefit/Cost Study, to assess the benefits associated with these advanced technology nacelles and formulate programs for developing these nacelles and low volume thrust reversers/spoilers to a state of technology readiness in the early 1990's. The study results established the design feasibility of advanced technology, slim line nacelles applicable to advanced technology, high bypass ratio turbofan engines. Design feasibility was also established for two low volume thrust reverse/spoiler concepts that meet or exceed the required effectiveness for these engines. These nacelle and thrust reverse/spoiler designs were shown to be applicable in engines with takeoff thrust sizes ranging from 24,000 to 60,000 pounds. The reduced weight, drag, and cost of the advanced technology nacelle installations relative to current technology nacelles offer a mission fuel burn savings ranging from 3.0 to 4.5 percent and direct operating cost plus interest improvements from 1.6 to 2.2 percent.

  18. The life cycles of six multi-center adaptive clinical trials focused on neurological emergencies developed for the Advancing Regulatory Science initiative of the National Institutes of Health and US Food and Drug Administration: Case studies from the Adaptive Designs Accelerating Promising Treatments Into Trials Project.

    Science.gov (United States)

    Guetterman, Timothy C; Fetters, Michael D; Mawocha, Samkeliso; Legocki, Laurie J; Barsan, William G; Lewis, Roger J; Berry, Donald A; Meurer, William J

    2017-01-01

    Clinical trials are complicated, expensive, time-consuming, and frequently do not lead to discoveries that improve the health of patients with disease. Adaptive clinical trials have emerged as a methodology to provide more flexibility in design elements to better answer scientific questions regarding whether new treatments are efficacious. Limited observational data exist that describe the complex process of designing adaptive clinical trials. To address these issues, the Adaptive Designs Accelerating Promising Treatments Into Trials project developed six, tailored, flexible, adaptive, phase-III clinical trials for neurological emergencies, and investigators prospectively monitored and observed the processes. The objective of this work is to describe the adaptive design development process, the final design, and the current status of the adaptive trial designs that were developed. To observe and reflect upon the trial development process, we employed a rich, mixed methods evaluation that combined quantitative data from visual analog scale to assess attitudes about adaptive trials, along with in-depth qualitative data about the development process gathered from observations. The Adaptive Designs Accelerating Promising Treatments Into Trials team developed six adaptive clinical trial designs. Across the six designs, 53 attitude surveys were completed at baseline and after the trial planning process completed. Compared to baseline, the participants believed significantly more strongly that the adaptive designs would be accepted by National Institutes of Health review panels and non-researcher clinicians. In addition, after the trial planning process, the participants more strongly believed that the adaptive design would meet the scientific and medical goals of the studies. Introducing the adaptive design at early conceptualization proved critical to successful adoption and implementation of that trial. Involving key stakeholders from several scientific domains early

  19. Methods for studying fuel management in advanced gas cooled reactors

    International Nuclear Information System (INIS)

    Buckler, A.N.; Griggs, C.F.; Tyror, J.G.

    1971-07-01

    The methods used for studying fuel and absorber management problems in AGRs are described. The basis of the method is the use of ARGOSY lattice data in reactor calculations performed at successive time steps. These reactor calculations may be quite crude but for advanced design calculations a detailed channel-by-channel representation of the whole core is required. The main emphasis of the paper is in describing such an advanced approach - the ODYSSEUS-6 code. This code evaluates reactor power distributions as a function of time and uses the information to select refuelling moves and determine controller positions. (author)

  20. Approaches to developing the capacity of health policy analysis institutes: a comparative case study

    Directory of Open Access Journals (Sweden)

    Bennett Sara

    2012-03-01

    Full Text Available Abstract Objectives To review and assess (i the factors that facilitate the development of sustainable health policy analysis institutes in low and middle income countries and (ii the nature of external support for capacity development provided to such institutes. Methods Comparative case studies of six health policy analysis institutes (3 from Asia and 3 from Africa were conducted. In each region an NGO institute, an institute linked to government and a university based institute were included. Data collection comprised document review, semi-structured interviews with stakeholders and discussion of preliminary findings with institute staff. Findings The findings are organized around four key themes: (i Financial resources: three of the institutes had received substantial external grants at start-up, however two of these institutes subsequently collapsed. At all but one institute, reliance upon short term, donor funding, created high administrative costs and unpredictability. (ii Human resources: the retention of skilled human resources was perceived to be key to institute success but was problematic at all but one institute. In particular staff often moved to better paid positions elsewhere once having acquired necessary skills and experience, leaving remaining senior staff with heavy workloads. (iii Governance and management: board structures and roles varied according to the nature of institute ownership. Boards made important contributions to organizational capacity through promoting continuity, independence and fund raising. Routine management systems were typically perceived to be strong. (iv Networks: linkages to policy makers helped promote policy influences. External networks with other research organizations, particularly where these were longer term institutional collaborations helped promote capacity. Conclusions The development of strong in-country analytical and research capacity to guide health policy development is critical, yet

  1. [Current status of bacteriological studies at prefectural and municipal public health institutes in Japan].

    Science.gov (United States)

    Shinomiya, Hiroto; Seto, Kazuko; Kawase, Jun; Arikawa, Kentaro; Funatogawa, Keiji; Suzuki, Masahiro; Kubota, Hiroaki; Shirabe, Komei

    2015-01-01

    Prefectural and municipal public health institutes are located in prefectures and ordinance-designated cities in Japan, and play a vital role in the regional surveillance of infectious diseases and foodborne illnesses. These institutes, in close cooperation with national institutes such as the National Institute of Infectious Diseases and the National Institute of Health Sciences, construct the national surveillance network for infectious diseases and their causative agents. Bacteriological examinations and studies on a variety of infectious diseases and foodborne illnesses are core activities of prefectural and municipal public health institutes, through which novel and important bacteriological findings have been acquired. In this article, we report the latest findings regarding bacteriological examinations/studies and interesting cases at these institutes, especially concerning foodborne illnesses, tuberculosis, and antimicrobial resistances.

  2. Conversation analysis and the study of social institutions: methodological, socio-cultural and epistemic considerations

    OpenAIRE

    Roca-Cuberes, Carles

    2014-01-01

    The objective of this study is to show how conversation analysis, a sociological discipline, approaches the study of social institutions. Social institutions are conceived as the crystallization of members’ communicative, interactional practices. Two institutional domains—psychiatric interviews and broadcast news interviews —and a specific interactional practice—‘formulations’—are examined in this study. The results show that (1) in psychiatric interviews the psychiatrist uses formulations to...

  3. Factors Affecting Women Enrolment In Technical Institutions In Tanzania A Case Study Of Arusha Technical College

    OpenAIRE

    Glory B. Kaaya; Dr. Esther Waiganjo

    2015-01-01

    Abstract The purpose of this study was to investigate the factors affecting women enrolment in Technical Institutions in Tanzania by focusing on the women. The study examined in detail the factors affecting women enrolment in Technical institutions and Arusha Technical College in particular as well as exploring sexual dynamics within Technical Institutions. Moreover a number of theoretical frameworks were concerned basing on the objectives a case study design was employed involving both qua...

  4. Champion comparison of prestigious nuclear research institutes by thirty-year research papers written in nuclear advanced countries

    International Nuclear Information System (INIS)

    Yanagisawa, Kazuaki

    2010-08-01

    A champion of research paper at JAERI and those of foreign prestigious nuclear research institutes (5 from the U.S., 3 from the France and 2 from the Germany) was studied taking the timeframe as long as 30 years (1978-2007) Tools for this bibliometric study were INIS, ECD, WOS and SCOPUS. The former two were general database collected all papers related to nuclear, while the latter two were specified database collected research papers submitted to journals for natural, social sciences and human learning. (1) INIS for the world-wide general tool focused on nuclear judged that JAERI (32,859 papers) was the champion and ORNL (32,395 papers) was the second position. (2) ECD for the US-oriented energy database judged that the ranking was of the order of ORNL(36,608 papers), ANL(26,530) and SNL(24,687). (3) The trend observed in the WOS for the US-oriented database roughly coincided with that of ECD, where ORNL(34,331 papers) was the champion, where JAERI was the 7th position. (4) SCOPUS, basically originated from the Europe judged that that ORNL (32,728 papers) was the champion, where JAERI (16,860) was the 7th position. (5) Different characteristics exhibited by individual databases can sometimes generate conflicting bibliometric results. This was true among INIS, ECD, WOS and SCOPUS when looking at trends between 5-year periods. It implies that results from analytical tools used in bibliometric studies should be viewed with careful consideration to learn of any influencing factors. (6) Use of INIS has predominance in Japan, and use of ECD has predominance in the U.S. Users from developed and developing countries assigned as the Member State of IAEA would be better served using INIS and ECD as the intellectual data source. As the recent trend, WOS and SCOPUS are used as the evaluation tools. (author)

  5. Pathological study on preoperative concurrent chemoradiation for advanced hypopharyngeal cancer

    International Nuclear Information System (INIS)

    Inoue, Toshiya; Nagata, Motoki; Yukawa, Hisaya

    2008-01-01

    Chemoradiotherapy is frequently applied as the first-line therapy for advanced hypopharyngeal cancer. However, organ-preserving therapy does not allow true pathological assessment of the effectiveness of the therapy. We therefore determined the following treatment modality for advanced hypopharyngeal cancer based on local findings upon the completion of radiotherapy at 40 Gy. Pathological assessments of 33 cases of advanced hypopharyngeal cancer who had undergone extended operation after chemoradiotherapy were performed. The pathological effects were 12 cases of Grade 1, 13 cases of Grade 2 and 8 cases of Grade 3. However, the rate of tumor-free cases was only 60% of the extended operation. In those cases, the local controlled lesions were well, however, distant metastases influenced the outcome; to control distant metastasis is a future issue. Additional studies to select a surgical approach will be needed. (author)

  6. Advanced language modeling approaches, case study: Expert search

    NARCIS (Netherlands)

    Hiemstra, Djoerd

    2008-01-01

    This tutorial gives a clear and detailed overview of advanced language modeling approaches and tools, including the use of document priors, translation models, relevance models, parsimonious models and expectation maximization training. Expert search will be used as a case study to explain the

  7. Ganglion Plexus Ablation in Advanced Atrial Fibrillation: The AFACT Study

    NARCIS (Netherlands)

    Driessen, Antoine H. G.; Berger, Wouter R.; Krul, Sébastien P. J.; van den Berg, Nicoline W. E.; Neefs, Jolien; Piersma, Femke R.; Chan Pin Yin, Dean R. P. P.; de Jong, Jonas S. S. G.; van Boven, WimJan P.; de Groot, Joris R.

    2016-01-01

    Patients with long duration of atrial fibrillation (AF), enlarged atria, or failed catheter ablation have advanced AF and may require more extensive treatment than pulmonary vein isolation. The aim of this study was to investigate the efficacy and safety of additional ganglion plexus (GP) ablation

  8. A Meta-Analysis of Advanced Organizer Studies.

    Science.gov (United States)

    Stone, Carol Leth

    1983-01-01

    Twenty-nine reports yielding 112 studies were analyzed with Glass's meta-analysis technique, and results were compared with predictions from Ausubel's model of assimilative learning. Overall, advance organizers were shown to be associated with increased learning and retention of material to be learned. (Author)

  9. A Longitudinal Study on Learner Career Advancement in MOOCs

    Science.gov (United States)

    Wang, Yuan; Paquette, Luc; Baker, Ryan

    2014-01-01

    In this paper, we present progress towards a longitudinal study of the post-course career advancement of MOOC learners. We present initial results and analysis plans for how to link this to in-course behaviour, towards better understanding the goals of all MOOC learners.

  10. Race/Ethnicity and Success in Academic Medicine: Findings From a Longitudinal Multi-Institutional Study.

    Science.gov (United States)

    Kaplan, Samantha E; Raj, Anita; Carr, Phyllis L; Terrin, Norma; Breeze, Janis L; Freund, Karen M

    2017-10-24

    To understand differences in productivity, advancement, retention, satisfaction, and compensation comparing underrepresented medical (URM) faculty with other faculty at multiple institutions. A 17-year follow-up was conducted of the National Faculty Survey, a random sample from 24 U.S. medical schools, oversampled for URM faculty. The authors examined academic productivity, advancement, retention, satisfaction, and compensation, comparing white, URM, and non-URM faculty. Retention, productivity, and advancement data were obtained from public sources for nonrespondents. Covariates included gender, specialty, time distribution, and years in academia. Negative binomial regression was used for count data, logistic regression for binary outcomes, and linear regression for continuous outcomes. In productivity analyses, advancement, and retention, 1,270 participants were included; 604 participants responded to the compensation and satisfaction survey. Response rates were lower for African American (26%) and Hispanic faculty (39%) than white faculty (52%, P career satisfaction, or compensation between URM and white faculty. URM and white faculty had similar career satisfaction, grant support, leadership, and compensation; URM faculty had fewer publications and were less likely to be promoted and retained in academic careers. Successful retention of URM faculty requires comprehensive institutional commitment to changing the academic climate and deliberative programming to support productivity and advancement.

  11. THE ACCOUNTING SYSTEM AND BUDGETARY FUNDING OF PUBLIC INSTITUTIONS. CASE STUDY: INSTITUTIONS FINANCED BY THE LOCAL COUNCIL OF GALATI

    Directory of Open Access Journals (Sweden)

    Radu Riana Iren

    2013-12-01

    Full Text Available Full of reforms, accounting science always tried to approach the concerned user requirements as return on capital employed and the complete picture of the operations that occurred during the financial year. For public sector entities, international financial reporting practices are referring to International Accounting Standards for the Public Sector (IPSAS. In this paper we intend to present a parallel between International Financial Reporting Standards (IFRS and IPSAS conjunction with the main aspects of budgetary lending highlighted through a case study aimed at the budget-funded institutions Galati Local Council in 2011-2013.

  12. Advanced turbine systems study system scoping and feasibility study

    Energy Technology Data Exchange (ETDEWEB)

    1993-04-01

    United Technologies Research Center, Pratt Whitney Commercial Engine Business, And Pratt Whitney Government Engine and Space Propulsion has performed a preliminary analysis of an Advanced Turbine System (ATS) under Contract DE-AC21-92MC29247 with the Morgantown Energy Technology Center. The natural gas-fired reference system identified by the UTC team is the Humid Air Turbine (HAT) Cycle in which the gas turbine exhaust heat and heat rejected from the intercooler is used in a saturator to humidify the high pressure compressor discharge air. This results in a significant increase in flow through the turbine at no increase in compressor power. Using technology based on the PW FT4000, the industrial engine derivative of the PW4000, currently under development by PW, the system would have an output of approximately 209 MW and an efficiency of 55.3%. Through use of advanced cooling and materials technologies similar to those currently in the newest generation military aircraft engines, a growth version of this engine could attain approximately 295 MW output at an efficiency of 61.5%. There is the potential for even higher performance in the future as technology from aerospace R D programs is adapted to aero-derivative industrial engines.

  13. Predictors of sexual risk behaviour among adolescents from welfare institutions in Malaysia: a cross sectional study

    OpenAIRE

    Farid, Nik Daliana Nik; Rus, Sulaiman Che'; Dahlui, Maznah; Al-Sadat, Nabilla; Aziz, Norlaili Abdul

    2014-01-01

    Background In welfare institutions, it is essential to address the health-related needs of adolescent populations who often engage in sexual activities. This study examines the association between individual and interpersonal factors concerning sexual risk behaviour (SRB) among adolescents in welfare institutions in Malaysia. Methods Data were derived from a cross-sectional study of 1082 adolescents in 22 welfare institutions located across Peninsular Malaysia in 2009. Using supervised self-a...

  14. Member Perceptions of Informal Science Institution Graduate Certificate Program: Case Study of a Community of Practice

    Science.gov (United States)

    Ball, Lois A.

    This research attempted to understand the experiences of a cohort of informal and formal science educators and informal science institution (ISI) community representatives during and after completion of a pilot graduate certificate program. Informal science educators (ISEs) find limited opportunities for professional development and support which influence their contributions to America's science literacy and school science education. This emergent design nested case study described how an innovative program provided professional development and enabled growth in participants' abilities to contribute to science literacy. Data were collected through interviews, participant observations, and class artifacts. The program by design and constituency was the overarching entity that accounted for members' experiences. Three principal aspects of the ISI certificate program and cohort which influenced perceptions and reported positive outcomes were (1) the cohort's composition and their collaborative activities which established a vigorous community of practice and fostered community building, mentoring, and networking, (2) long term program design and implementation which promoted experiential learning in a generative classroom, and (3) ability of some members who were able to be independent or autonomous learners to embrace science education reform strategies for greater self-efficacy and career advancement. This research extends the limited literature base for professional development of informal science educators and may benefit informal science institutions, informal and formal science educators, science education reform efforts, and public education and science-technology-society understanding. The study may raise awareness of the need to establish more professional development opportunities for ISEs and to fund professional development. Further, recognizing and appreciating informal science educators as a diverse committed community of professionals who positively

  15. Study of advanced fuel system concepts for commercial aircraft

    Science.gov (United States)

    Coffinberry, G. A.

    1985-01-01

    An analytical study was performed in order to assess relative performance and economic factors involved with alternative advanced fuel systems for future commercial aircraft operating with broadened property fuels. The DC-10-30 wide-body tri-jet aircraft and the CF6-8OX engine were used as a baseline design for the study. Three advanced systems were considered and were specifically aimed at addressing freezing point, thermal stability and lubricity fuel properties. Actual DC-10-30 routes and flight profiles were simulated by computer modeling and resulted in prediction of aircraft and engine fuel system temperatures during a nominal flight and during statistical one-day-per-year cold and hot flights. Emergency conditions were also evaluated. Fuel consumption and weight and power extraction results were obtained. An economic analysis was performed for new aircraft and systems. Advanced system means for fuel tank heating included fuel recirculation loops using engine lube heat and generator heat. Environmental control system bleed air heat was used for tank heating in a water recirculation loop. The results showed that fundamentally all of the three advanced systems are feasible but vary in their degree of compatibility with broadened-property fuel.

  16. Advanced supersonic propulsion study. [with emphasis on noise level reduction

    Science.gov (United States)

    Sabatella, J. A. (Editor)

    1974-01-01

    A study was conducted to determine the promising propulsion systems for advanced supersonic transport application, and to identify the critical propulsion technology requirements. It is shown that noise constraints have a major effect on the selection of the various engine types and cycle parameters. Several promising advanced propulsion systems were identified which show the potential of achieving lower levels of sideline jet noise than the first generation supersonic transport systems. The non-afterburning turbojet engine, utilizing a very high level of jet suppression, shows the potential to achieve FAR 36 noise level. The duct-heating turbofan with a low level of jet suppression is the most attractive engine for noise levels from FAR 36 to FAR 36 minus 5 EPNdb, and some series/parallel variable cycle engines show the potential of achieving noise levels down to FAR 36 minus 10 EPNdb with moderate additional penalty. The study also shows that an advanced supersonic commercial transport would benefit appreciably from advanced propulsion technology. The critical propulsion technology needed for a viable supersonic propulsion system, and the required specific propulsion technology programs are outlined.

  17. Can Internationalisation Really Lead to Institutional Competitive Advantage?--A Study of 16 Dutch Public Higher Education Institutions

    Science.gov (United States)

    De Haan, Haijing

    2014-01-01

    Public higher education institutions (PHEIs) have widely acknowledged a positive relationship between internationalization and their institutional competitive advantage enhancement. Although some concerns have been raised by practitioners and researchers about whether institutional competitive advantage can be enhanced given the current ways of…

  18. A longitudinal and experimental study of the impact of knowledge on the bases of institutional trust.

    Science.gov (United States)

    PytlikZillig, Lisa M; Kimbrough, Christopher D; Shockley, Ellie; Neal, Tess M S; Herian, Mitchel N; Hamm, Joseph A; Bornstein, Brian H; Tomkins, Alan J

    2017-01-01

    This study examined a knowledge-centered theory of institutional trust development. In the context of trust in water regulatory institutions, the moderating impact of knowledge was tested to determine if there were longitudinal changes in the bases of institutional trust as a function of increases in knowledge about a target institution. We hypothesized that as people learn about an institution with which they were previously unfamiliar, they begin to form more nuanced perceptions, distinguishing the new institution from other institutions and relying less upon their generalized trust to estimate their trust in that institution. Prior to having specific, differential information about a new institution, we expected institutional trust to be a function of generalized trust variables such as dispositional trust and trust in government. The longitudinal experiment involved 185 college students randomly assigned to one of three information conditions. Every 3 months for 15 months, participants read information about water regulatory institutions or a control institution. At each time point, participants reported their trust in and perceptions of the trust- and distrust-worthiness of the water regulatory institutions. Participants also completed measures of knowledge of water regulatory institutions, dispositional trust, and governmental trust. Our manipulation check indicated that, as expected, those in the experimental group increased in subjective knowledge of water regulatory institutions to a greater extent than those in the control condition. Consistent with our hypotheses, there was some evidence that, compared to the control group, the experimental group relied less on their general trust in government as a basis for their trust in water regulatory institutions. However, contrary to our hypotheses, there was no evidence the experimental group relied less on dispositional trust as a basis for institutional trust. There also was some evidence the experimental

  19. A longitudinal and experimental study of the impact of knowledge on the bases of institutional trust.

    Directory of Open Access Journals (Sweden)

    Lisa M PytlikZillig

    Full Text Available This study examined a knowledge-centered theory of institutional trust development. In the context of trust in water regulatory institutions, the moderating impact of knowledge was tested to determine if there were longitudinal changes in the bases of institutional trust as a function of increases in knowledge about a target institution. We hypothesized that as people learn about an institution with which they were previously unfamiliar, they begin to form more nuanced perceptions, distinguishing the new institution from other institutions and relying less upon their generalized trust to estimate their trust in that institution. Prior to having specific, differential information about a new institution, we expected institutional trust to be a function of generalized trust variables such as dispositional trust and trust in government. The longitudinal experiment involved 185 college students randomly assigned to one of three information conditions. Every 3 months for 15 months, participants read information about water regulatory institutions or a control institution. At each time point, participants reported their trust in and perceptions of the trust- and distrust-worthiness of the water regulatory institutions. Participants also completed measures of knowledge of water regulatory institutions, dispositional trust, and governmental trust. Our manipulation check indicated that, as expected, those in the experimental group increased in subjective knowledge of water regulatory institutions to a greater extent than those in the control condition. Consistent with our hypotheses, there was some evidence that, compared to the control group, the experimental group relied less on their general trust in government as a basis for their trust in water regulatory institutions. However, contrary to our hypotheses, there was no evidence the experimental group relied less on dispositional trust as a basis for institutional trust. There also was some evidence

  20. Academe's Glass Ceiling: Societal, Professional-Organizational, and Institutional Barriers to the Career Advancement of Academic Women.

    Science.gov (United States)

    Bain, Olga; Cummings, William

    2000-01-01

    A survey of 10 national systems of higher education found that less than 10 percent of professors were women, and the proportion of female professors was negatively related to institutional prestige. This academic "glass ceiling" was related to women's shorter careers, tenure issues during hard times, and women's lower level of academic…

  1. Seeing It through: Advanced Strategies "for" Influencing Education Policy. Education Grantmakers Institute (Cambridge, Massachusetts, May 19-21, 2009)

    Science.gov (United States)

    Mackinnon, Anne

    2009-01-01

    "No education grantmaker can afford to ignore public policy. Local, state and federal policies shape the context in which we work by establishing education standards, allocating resources and setting priorities for people working in education." So begins the report on Grantmakers for Educations' 2005 Grantmakers Institute, Foundation…

  2. The Hispanic Association of Colleges and Universities and Hispanic-Serving Institutions: Partners in the Advancement of Hispanic Higher Education

    Science.gov (United States)

    Calderon Galdeano, Emily; Flores, Antonio R.; Moder, John

    2012-01-01

    The relationship between the Hispanic Association of Colleges and Universities (HACU) and the recognition of Hispanic-Serving Institutions (HSIs) occurs at the federal level. HACU's origins and the legislative history of the HSI designation in federal law are explored. The demographic growth and corresponding importance of Hispanics in the…

  3. Participation without Parity in U.S. Higher Education: Gender, Fields of Study, and Institutional Selectivity

    Science.gov (United States)

    Mullen, Ann L.; Baker, Jayne

    2015-01-01

    While women now earn more bachelor's degrees than men in many parts of the world, large gender gaps persist in fields of study, and women remain underrepresented in the most prestigious institutions. This study updates and extends the literature on gender disparities in higher education by comparing the selectivity of the institutions where men…

  4. Comparative Analysis of Institutional Policy Definitions of Plagiarism: A Pan-Canadian University Study

    Science.gov (United States)

    Eaton, Sarah Elaine

    2017-01-01

    This article shares the findings of a study investigating institutional policy definitions of plagiarism at twenty English-speaking Canadian universities. The types of primary sources consulted for this study included: (1) university academic calendars for 2016-2017, (2) institutional policies on academic misconduct, and (3) student academic codes…

  5. Soviet scientists in chinese institutes: A historical study of cooperation between the two academies of sciences in 1950s.

    Science.gov (United States)

    Zhang, Jiuchen; Yu, Feklova T

    2018-03-01

    In the 1950s, the Chinese Academy of Sciences (CAS) engaged in close cooperation with the Soviet Academy of Sciences. The CAS sent scientists to the Soviet Academy to work as interns, study for advanced degrees, or engage in academic cooperation, and a large number of Soviet scientists were invited by the various institutes of the CAS to come to China to give lectures, direct research, help make scientific plans, and collaborate. The comprehensive cooperation between the two academies was launched at a time when the CAS institutes were in their embryonic stage, which suggests that the better-established Soviet scientists had the opportunity to play a dominate role. But the reality is not so straightforward. The case studies in this paper suggest that besides the influence of compatible political movements in China and the Soviet Union and bilateral ties between these two nations' scientific institutes, disharmony in actual working relationships prevented Soviet scientists from playing the role they might have envisioned within the CAS institutes. The rapid development of the cooperative relationship in a short span of time, combined with lack of experience on both sides, made for a disharmonious collaboration. Copyright © 2018 Elsevier Ltd. All rights reserved.

  6. Planning a multi-institutional information for development study centre

    CSIR Research Space (South Africa)

    Moreno, A

    2010-05-01

    Full Text Available . The I4D Study Centre tasks are to increase both the research expertise pool available for Meraka and the partner university, and the joint development of study programs with universities that will prepare students for a researcher career with an ICT4D...

  7. The Advanced Gamma-ray Imaging System (AGIS): Simulation Studies

    Science.gov (United States)

    Fegan, Stephen; Buckley, J. H.; Bugaev, S.; Funk, S.; Konopelko, A.; Maier, G.; Vassiliev, V. V.; Simulation Studies Working Group; AGIS Collaboration

    2008-03-01

    The Advanced Gamma-ray Imaging System (AGIS) is a concept for the next generation instrument in ground-based very high energy gamma-ray astronomy. It has the goal of achieving significant improvement in sensitivity over current experiments. We present the results of simulation studies of various possible designs for AGIS. The primary characteristics of the array performance, collecting area, angular resolution, background rejection, and sensitivity are discussed.

  8. The Advanced Gamma-ray Imaging System (AGIS): Simulation Studies

    OpenAIRE

    Maier, G.; Collaboration, for the AGIS

    2009-01-01

    The Advanced Gamma-ray Imaging System (AGIS) is a next-generation ground-based gamma-ray observatory being planned in the U.S. The anticipated sensitivity of AGIS is about one order of magnitude better than the sensitivity of current observatories, allowing it to measure gammaray emmission from a large number of Galactic and extra-galactic sources. We present here results of simulation studies of various possible designs for AGIS. The primary characteristics of the array performance - collect...

  9. Advances in thermal-hydraulic studies of a transmutation advanced device for sustainable energy applications

    International Nuclear Information System (INIS)

    Fajardo, Laura Garcia; Castells, Facundo Alberto Escriva; Lira, Carlos Brayner de Olivera

    2013-01-01

    The Transmutation Advanced Device for Sustainable Energy Applications (TADSEA) is a pebble-bed Accelerator Driven System (ADS) with a graphite-gas configuration, designed for nuclear waste trans- mutation and for obtaining heat at very high temperatures to produce hydrogen. In previous work, the TADSEA's nuclear core was considered as a porous medium performed with a CFD code and thermal-hydraulic studies of the nuclear core were presented. In this paper, the heat transfer from the fuel to the coolant was analyzed for three core states during normal operation. The heat transfer inside the spherical fuel elements was also studied. Three critical fuel elements groups were defined regarding their position inside the core. Results were compared with a realistic CFD model of the critical fuel elements groups. During the steady state, no critical elements reached the limit temperature of this type of fuel. (author)

  10. Digital preservation and institutional repositories: case study of ...

    African Journals Online (AJOL)

    Irene Nyachiro

    The study investigated the strategies used by ... data. Lord et al. argue that much needs to be done to enable this data to remain available and valid to ... cycle perspective facilitates continuity of .... The major modes of scholarly preservation.

  11. NATO Advanced Study Institute on recording or otherwise, without written permission from the Publisher, with the exception a computer system, for exclusive use by the purchaser of the work. and Elastic Active Media Morphogenesis Through the Interplay of Nonlinear Chemical Instabilities

    CERN Document Server

    Borckmans, P; Khokhlov, A. R; Métens, S; Chemomechanical Instabilities in Responsive Materials

    2009-01-01

    This volume contains a selection of the papers presented by renowned specialists of each field. It is the first book in which the communities of nonlinear chemists and gel specialist communicate and show how interactions between the two fields can actually produce working devices based on the transduction of chemical to mechanical energy and vice-versa. Beside subtle ways of using the slaving of responsive materials devices to oscillatory reactions, emphasis is brought on emerging properties that are possessed by neither of the separated constituents. Several contributions on these aspects are included, in relation to their potential relevance to biological, medical and technological applications. The whole constitutes a specific multidisciplinary "new" field. Both advanced and basic aspects of the two fields can be found the this collection of lectures. The book will not only benefit to doctoral students or young post-docs to learn the ropes of both subjects, but also to active researchers from one field, to...

  12. Conceptual design study on advanced aqueous reprocessing system for fast reactor fuel cycle

    International Nuclear Information System (INIS)

    Takata, Takeshi; Koma, Yoshikazu; Sato, Koji; Kamiya, Masayoshi; Shibata, Atsuhiro; Nomura, Kazunori; Ogino, Hideki; Koyama, Tomozo; Aose, Shin-ichi

    2003-01-01

    As a feasibility study on commercialized fast reactor cycle system, a conceptual design study is being progressed for the aqueous and pyrochemical processes from the viewpoint of economical competitiveness, efficient utilization of resources, decreasing environmental impact and proliferation resistance in Japan Nuclear Cycle Development Institute (JNC). In order to meet above-mentioned requirements, the survey on a range of reprocessing technologies and the evaluation of conceptual plant designs against targets for the future fast reactor cycle system have been implemented as the fist phase of the feasibility study. For an aqueous reprocessing process, modification of the conventional PUREX process (a solvent extraction process with purification of U/Pu, with nor recovery of minor actinides (MA)) and investigation of alternatives for the PUREX process has been carried out and design study of advanced aqueous reprocessing system and its alternatives has been conducted. The conceptual design of the advanced aqueous reprocessing system has been updated and evaluated by the latest R and D results of the key technologies such as crystallization, single-cycle extraction, centrifugal contactors, recovery of Am/Cm and waste processing. In this paper, the outline of the design study and the current status of development for advanced aqueous reprocessing system, NEXT process, are mentioned. (author)

  13. Employee Retention Factors For South African Higher Education Institutions: A Case Study

    Directory of Open Access Journals (Sweden)

    F. G. Netswera

    2005-11-01

    Full Text Available The success of the most competitive companies throughout the world, including higher education institutions, lies in their highly skilled employees on which these institutions spend millions to retain. Literature reveals the cost of losing best employees to be enormous – beyond monetary quantification. Also worth noting is that the loss of one competent employee to a competitor institution strengthens the competitor’s advantage. This case study analysed human resources turnover data, and interviewed academic managers and employees in order to examine the possible employee retention factors for a higher education institution in South Africa. The findings reveal different institutional interests between institutional managers and employees. The former are concerned more about profits, business sustenance and justification for spending, while the latter are driven by introverted interests such as development, monetary rewards and personal fulfilment.

  14. Imaging characteristics of supratentorial ependymomas: Study on a large single institutional cohort with histopathological correlation.

    Science.gov (United States)

    Mangalore, Sandhya; Aryan, Saritha; Prasad, Chandrajit; Santosh, Vani

    2015-01-01

    Supratentorial ependymoma (STE) is a tumor whose unique clinical and imaging characteristics have not been studied. Histopathologically, they resemble ependymoma elsewhere. We retrospectively reviewed the imaging findings with clinicopathological correlation in a large number of patients with STE to identify these characteristics. Computed tomography (CT) magnetic resonance images (MRI), pathology reports, and clinical information from 41 patients with pathology-confirmed STE from a single institution were retrospectively reviewed. CT and MRI findings including location, size, signal intensity, hemorrhage, and enhancement pattern were tabulated and described separately in intraventricular and intraparenchymal forms. STE was more common in pediatric age group and intraparenchymal was more common than intraventricular form. The most common presentation was features of raised intracranial tension. There were equal numbers of Grade II and Grade III tumors. The imaging characteristics in adult and pediatric age group were similar. The tumor was large and had both solid and cystic components. Advanced imaging such as diffusion, perfusion, and spectroscopy were suggestive of high-grade tumor. Only differentiating factor between Grade II and Grade III was the presence of calcification. 1234 rule and periwinkle sign which we have described in this article may help characterize this tumor on imaging. This series expands the clinical and imaging spectrum of STE and identifies characteristics that should suggest consideration of this uncommon diagnosis.

  15. Institution Based Prospective Cross-Sectional Study on Patterns of ...

    African Journals Online (AJOL)

    BACKGROUND: Every year, millions of babies are born and a large proportion of them are being admitted to hospital for various indications. This study was conducted to identify the general characteristics, disease spectrum and common causes of Neonatal morbidity and mortality at Gondar University Hospital, Neonatal ...

  16. Instituting Cultural Change at a Major Organization: A Case Study

    Science.gov (United States)

    Dulek, Ronald E.

    2015-01-01

    This article examines the development and implementation of a strategic cultural change program from a case study perspective. Initially, the article describes how the program was developed, including an explanation as to how a communication component was integrated into the program from inception. This integration helped reduce the anxiety that…

  17. Factors associated with institutional delivery in Dangila district, North West Ethiopia: a cross-sectional study.

    Science.gov (United States)

    Demilew, Yeshalem Mulugeta; Gebregergs, Gebremedhin Berhe; Negusie, Azezu Asres

    2016-03-01

    Childbirth in a health institution has been shown to be associated with lower rates of maternal and neonatal mortality. However, about 85% of mothers in Ethiopia deliver at home. To assess factors associated with institutional delivery service utilization among women who gave birth within one year prior to the study in Dangila district. A cross-sectional study was conducted from February 01-28, 2015. A total of 763 mothers were interviewed using structured questionnaire. SPSS version 20 was used for analysis. Crude and adjusted Odds ratios were computed for selected variables. A P-value less than 0.05 was considered statistical significant. Only 18.3% of mothers gave birth at health facilities. Knowledge on danger signs [AOR=2.0, 95% CI: (1.1, 3.4)], plan to give birth at health institution [AOR=5.4, 95% CI: (3.0, 9.6)], having ANC follow up during pregnancy [AOR=12.9, 95% CI: (5.0, 33.3)] and time taken to get to a nearby health institution [AOR=5.1, 95% CI: (2.9, 9.1)] were associated with institutional delivery service utilization. Institutional delivery was very low. Knowledge about danger signs, having ANC visits, and time were factors associated with institutional delivery service utilization. Thus, the findings recommend repeated re-enforcement of institutional delivery service utilization through professionals. And also, the findings recommend promotion of institutional delivery service utilization through mass media.

  18. The path dependency theory: analytical framework to study institutional integration. The case of France.

    Science.gov (United States)

    Trouvé, Hélène; Couturier, Yves; Etheridge, Francis; Saint-Jean, Olivier; Somme, Dominique

    2010-06-30

    The literature on integration indicates the need for an enhanced theorization of institutional integration. This article proposes path dependence as an analytical framework to study the systems in which integration takes place. PRISMA proposes a model for integrating health and social care services for older adults. This model was initially tested in Quebec. The PRISMA France study gave us an opportunity to analyze institutional integration in France. A qualitative approach was used. Analyses were based on semi-structured interviews with actors of all levels of decision-making, observations of advisory board meetings, and administrative documents. Our analyses revealed the complexity and fragmentation of institutional integration. The path dependency theory, which analyzes the change capacity of institutions by taking into account their historic structures, allows analysis of this situation. The path dependency to the Bismarckian system and the incomplete reforms of gerontological policies generate the coexistence and juxtaposition of institutional systems. In such a context, no institution has sufficient ability to determine gerontology policy and build institutional integration by itself. Using path dependence as an analytical framework helps to understand the reasons why institutional integration is critical to organizational and clinical integration, and the complex construction of institutional integration in France.

  19. Motivation to study dental professions in one London Dental Institute.

    Science.gov (United States)

    Belsi, A; Asimakopoulou, K; Donaldson, N; Gallagher, J

    2014-02-01

    While past research has explored dental students' motivation to study, there is limited understanding in the reasons behind career choice for hygienists/therapists and dental nurses. The aim of this study was to investigate simultaneously the views of students of dentistry, hygiene/therapy and dental nursing in King's College London and explore similarities or differences in career choice. All first-year students were invited to the questionnaire survey, exploring motivation to study using a 23-item instrument. Data were analysed using SPSS v18; statistical analysis included one-way analyses of variance and factor analysis. The overall response rate to the study was 75% (n = 209). Ten out of 23 factors were considered important by more than 80% of respondents, with 'job security' (93.8%), 'desire to work with people' (88%) and 'degree leading to recognised job' (87.5%) being top three. Analysis suggested that 52% of the total variation in motivating influences was explained by four factors: 'features of the job' (26%), 'education/skills' (11%), 'public service' (8%) and 'careers-advising' (7%); at group level 'features of the job' were significantly more important for the direct entrants to dentistry (P = 0.001). The findings suggest that across groups students were motivated to study by common influences reflecting altruistic, but also pragmatic and realistic motives, while 'features of the job' were more important for the direct entrants to dentistry. © 2013 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  20. Concurrent chemoradiotherapy for advanced cervical cancer. A pilot study

    International Nuclear Information System (INIS)

    Kodama, Junichi; Hashimoto, Ichiro; Seki, Noriko; Hongo, Atsushi; Mizutani, Yasushi; Miyagi, Yasunari; Yoshinouchi, Mitsuo; Kudo, Takafumi

    2001-01-01

    Recently, attempts have made to use radiotherapy in combination with chemotherapy in various solid tumors including cervical cancer. Twenty-four patients with locally advanced cervical cancer were treated with concurrent Carboplatin (16-24 mg/m 2 /day) or Nedaplatin (20 mg/m 2 /week) and conventional radiotherapy. Of 13 evaluable patients, there were nine complete responders and four partial responders. There was no renal damage or grade 4 hematological toxicity. Gastrointestinal adverse reactions were mild. One patient had grade 3 dermatologic toxicity after delayed radiation therapy. This pilot study suggests that daily Carboplatin or weekly Nedaplatin administered with standard radiation therapy is safe, well-tolerated, and thus may be useful as a radiation sensitizer in the treatment of locally advanced cervical cancer. (author)

  1. Advanced Exploration Systems Water Architecture Study Interim Results

    Science.gov (United States)

    Sargusingh, Miriam J.

    2013-01-01

    The mission of the Advanced Exploration System (AES) Water Recovery Project (WRP) is to develop advanced water recovery systems that enable NASA human exploration missions beyond low Earth orbit (LEO). The primary objective of the AES WRP is to develop water recovery technologies critical to near-term missions beyond LEO. The secondary objective is to continue to advance mid-readiness-level technologies to support future NASA missions. An effort is being undertaken to establish the architecture for the AES Water Recovery System (WRS) that meets both near- and long-term objectives. The resultant architecture will be used to guide future technical planning, establish a baseline development roadmap for technology infusion, and establish baseline assumptions for integrated ground and on-orbit Environmental Control and Life Support Systems definition. This study is being performed in three phases. Phase I established the scope of the study through definition of the mission requirements and constraints, as well as identifying all possible WRS configurations that meet the mission requirements. Phase II focused on the near-term space exploration objectives by establishing an International Space Station-derived reference schematic for long-duration (>180 day) in-space habitation. Phase III will focus on the long-term space exploration objectives, trading the viable WRS configurations identified in Phase I to identify the ideal exploration WRS. The results of Phases I and II are discussed in this paper.

  2. Study of advanced rotary combustion engines for commuter aircraft

    Science.gov (United States)

    Berkowitz, M.; Jones, C.; Myers, D.

    1983-01-01

    Performance, weight, size, and maintenance data for advanced rotary aircraft engines suitable for comparative commuter aircraft system evaluation studies of alternate engine candidates are provided. These are turbocharged, turbocompounded, direct injected, stratified charge rotary engines. Hypothetical engines were defined (an RC4-74 at 895 kW and an RC6-87 at 1490 kW) based on the technologies and design approaches used in the highly advanced engine of a study of advanced general aviation rotary engines. The data covers the size range of shaft power from 597 kW (800 hp) to 1865 kW (2500 hp) and is in the form of drawings, tables, curves and written text. These include data on internal geometry and configuration, installation information, turbocharging and turbocompounding arrangements, design features and technologies, engine cooling, fuels, scaling for weight size BSFC and heat rejection for varying horsepower, engine operating and performance data, and TBO and maintenance requirements. The basic combustion system was developed and demonstrated; however the projected power densities and performance efficiencies require increases in engine internal pressures, thermal loading, and rotative speed.

  3. Recent case studies and advancements in probabilistic risk assessment

    International Nuclear Information System (INIS)

    Garrick, B.J.

    1985-01-01

    During the period from 1977 to 1984, Pickard, Lowe and Garrick, Inc., had the lead in preparing several full scope probabilistic risk assessments for electric utilities. Five of those studies are discussed from the point of view of advancements and lessons learned. The objective and trend of these studies is toward utilization of the risk models by the plant owners as risk management tools. Advancements that have been made are in presentation ad documentation of the PRAs, generation of more understandable plant level information, and improvements in methodology to facilitate technology transfer. Specific areas of advancement are in the treatment of such issues as dependent failures, human interaction, and the uncertainty in the source term. Lessons learned cover a wide spectrum and include the importance of plant specific models for meaningful risk management, the role of external events in risk, the sensitivity of contributors to choice of risk index, and the very important finding that the public risk is extremely small. The future direction of PRA is to establish less dependence on experts for in-plant application. Computerizing the PRAs such that they can be accessed on line and interactively is the key

  4. INCIDENCE OF OVARIAN CYST IN HYPOTHYROIDISM: AN INSTITUTIONAL STUDY

    Directory of Open Access Journals (Sweden)

    Ramesan C

    2016-09-01

    Full Text Available BACKGROUND Primary hypothyroidism is the decrease in production and secretion of thyroid hormones by the thyroid gland. This is characterised by slackening of metabolism and leading to multiple system impairment. The important aetiological factors for primary hypothyroidism are congenital, iodine deficiency, autoimmune thyroiditis and iatrogenic.[1] Ovarian cysts are a common cause for gynaecological surgeries. The aetiology[2] of ovarian cysts can vary greatly including benign or malignant tumours, endometriosis and inflammation, etc. However, some cysts are direct result of endocrine disorders and do not require surgery. Hypothyroidism may cause reproductive and endocrinological disorders as well. The aetiopathogenesis is complex. In 1960 Van Wyk and Grumbach first described the relation between ovarian cyst and hypothyroidism. They proposed that there was a hormonal overlap in the pituitary feedback mechanism. It is due to the fact that TSH, GH, FSH and LH are all glycoproteins with a common alpha chain and may thus cross react. High TSH could produce FSH and LH like activity leading to luteinised ovarian cyst. The TRH may also act on pituitary cells to stimulate gonadotropin release and hence FSH and LH. Other postulated mechanisms are increased ovarian sensitivity to gonadotropins, altered metabolism of oestrogen, hypothalamopituitary dysfunction and altered prolactin metabolism. AIMS To study the percentage of ovarian cyst among the diagnosed cases of primary hypothyroidism and then to find out the association between hypothyroidism and ovarian cyst. To study the relation between level of TSH and size of ovarian cyst. To study the percentage of ovarian cyst among patients with TSH 100 mIU/L separately. SETTINGS Study Design: Descriptive: Cross-sectional study. Duration: One year. Period: March 2013 to February 2014. Sample Size: 100. Study Area: Government Medical College, Calicut. INCLUSION CRITERIA Female patients of age more than 12

  5. Introducing nerve-sparing approach during minimally invasive radical hysterectomy for locally-advanced cervical cancer: A multi-institutional experience.

    Science.gov (United States)

    Raspagliesi, Francesco; Bogani, Giorgio; Spinillo, Arsenio; Ditto, Antonino; Bogliolo, Stefano; Casarin, Jvan; Leone Roberti Maggiore, Umberto; Martinelli, Fabio; Signorelli, Mauro; Gardella, Barbara; Chiappa, Valentina; Scaffa, Cono; Ferrero, Simone; Cromi, Antonella; Lorusso, Domenica; Ghezzi, Fabio

    2017-11-01

    To evaluate the impact of nerve-sparing (NS) approach on outcomes of patients undergoing minimally invasive radical hysterectomy (MRH) for locally advanced stage cervical cancer (LACC). Data of consecutive patients undergoing minimally invasive surgery for LACC were retrospectively retrieved in a multi-institutional setting from 2009 to 2016. All patients included had minimally invasive class III radical hysterectomy (MRH or NS-MRH). Propensity matching algorithm was used to decrease possible allocation bias when comparing outcomes between groups. Overall, 83 patients were included. The prevalence of patients undergoing NS approach increased aver the study period (from 7% in the year 2009-2010 to 97% in the year 2015-2016; p-for-trend < 0.001). NS-MRH and MRH were performed in 47 (57%) and 36 (43%) patients, respectively. After the application the propensity-matching algorithm, we compared 35 patients' pair (total 70 patients). Postoperative complications rate was similar between groups. Patients undergoing NS-LRH experienced shorter hospital stay than patients undergoing LRH (3.6 vs. 5.0 days). 60-day pelvic floor dysfunction rates, including voiding, fecal and sexual alterations, were lower in the NS group in comparison to control group (p = 0.02). Five-year disease-free (p = 0.77) and overall (p = 0.36) survivals were similar comparing NS-MRH with MRH. The implementation of NS approach in the setting of LACC improves patients' outcomes, minimizing pelvic dysfunction rates. NS approach has not detrimental effects on survival outcomes. Copyright © 2017 Elsevier Ltd, BASO ~ The Association for Cancer Surgery, and the European Society of Surgical Oncology. All rights reserved.

  6. An Empirical Study on Green Innovation Efficiency in the Green Institutional Environment

    OpenAIRE

    Yang Gao; Sang-Bing Tsai; Xingqun Xue; Tingzhen Ren; Xiaomin Du; Quan Chen; Jiangtao Wang

    2018-01-01

    Previous studies have found that reverse technology spillover effects can promote industrial technology modernization in developing countries. However, it is still unknown whether reverse technology spillover effects can improve green innovation efficiency in developing countries. In particular, institutional uncertainties characteristic of transition economies have a significant impact on industrial modernization. Therefore, researching the impact of the institutional environment on the rela...

  7. Availability and Accessibility in an Open Access Institutional Repository: A Case Study

    Science.gov (United States)

    Lee, Jongwook; Burnett, Gary; Vandegrift, Micah; Baeg, Jung Hoon; Morris, Richard

    2015-01-01

    Introduction: This study explores the extent to which an institutional repository makes papers available and accessible on the open Web by using 170 journal articles housed in DigiNole Commons, the institutional repository at Florida State University. Method: To analyse the repository's impact on availability and accessibility, we conducted…

  8. Emerging Economies, Institutional Voids, and Innovation Drivers : A Study in India

    NARCIS (Netherlands)

    Voeten, Jaap; Saiyed, Abrar Ali; Dutta, Dev K.

    Research has highlighted the importance of the institutional context on innovation and entrepreneurship. The focus of this qualitative research was to study small and medium enterprises (SMEs) in the manufacturing sector in India with the purpose of understanding how institutional voids affect the

  9. Case Study of a Post-Secondary Institution and Its Response to Student Homelessness

    NARCIS (Netherlands)

    K. Kovacs Burns (Kathy); M.S. Richter (Magdalena); Y. Mao (Yuping); S. Mogale (Shirley); M. Danko (Margaret)

    2016-01-01

    textabstractFrom the moment students are accepted into post-secondary institutions, the focus is on their studies and successful completion. Far less is known about what institutions understand about students’ personal stresses and issues with their finances, housing and especially student

  10. Circulation Policies for External Users: A Comparative Study of Public Urban Research Institutions

    Science.gov (United States)

    Weare, William H., Jr.; Stevenson, Matthew

    2012-01-01

    This article is a study of the policies that govern the use of the university library by external users at Indiana University-Purdue University Indianapolis (IUPUI) and 12 peer institutions used by IUPUI for comparative purposes. A search of each institution's Web site was conducted as well as interviews with circulation librarians and managers.…

  11. Conceptual design study advanced concepts test (ACT) facility

    Energy Technology Data Exchange (ETDEWEB)

    Zaloudek, F.R.

    1978-09-01

    The Advanced Concepts Test (ACT) Project is part of program for developing improved power plant dry cooling systems in which ammonia is used as a heat transfer fluid between the power plant and the heat rejection tower. The test facility will be designed to condense 60,000 lb/hr of exhaust steam from the No. 1 turbine in the Kern Power Plant at Bakersfield, CA, transport the heat of condensation from the condenser to the cooling tower by an ammonia phase-change heat transport system, and dissipate this heat to the environs by a dry/wet deluge tower. The design and construction of the test facility will be the responsibility of the Electric Power Research Institute. The DOE, UCC/Linde, and the Pacific Northwest Laboratories will be involved in other phases of the project. The planned test facilities, its structures, mechanical and electrical equipment, control systems, codes and standards, decommissioning requirements, safety and environmental aspects, and energy impact are described. Six appendices of related information are included. (LCL)

  12. Low Vision Research at the Schepens Eye Research Institute

    National Research Council Canada - National Science Library

    D'Amore, Patricia

    2003-01-01

    This research proposal, Low Vision at the Schepens Eye Research Institute, is a collaborative effort on the part of four Investigators at the Institute whose goal is to advance the studies on low vision...

  13. Cyclophosphamide-hydroxycamptothecin as second-line chemotherapy for advanced Ewing's sarcoma: experience of a single institution.

    Science.gov (United States)

    Han, Kun; Sun, Yuanjue; Zhang, Jianjun; He, Aina; Zheng, Shui'er; Shen, Zan; Yao, Yang

    2014-06-01

    To investigate the feasibility and efficacy of cyclophosphamide (CTX)-hydroxycamptothecin (HCPT) as second-line chemotherapy on advanced Ewing's sarcoma. From April 2009 to November 2010, 27 patients with advanced Ewing's sarcoma who had progressive disease after the first-line chemotherapy regimen of vincristine, dactinomycin and cyclophosphamide and ifosfamide and etoposide were retrospectively reviewed in this analysis. CTX was given (0.6 g/m(2), i.v. push day 1) and HCPT (6 mg/m(2), i.v. drip days 1-5) as second-line chemotherapy every 3 weeks. The primary end-point was overall response rate, the secondary end-point included progression-free, overall survival, disease control rate and toxicities. A total of 134 cycles were given, median four cycles per patient (range 2-6). Overall response rate was 30% and disease control rate was 82%, with two complete response (8%), six partial remission (22%) and 14 stable disease (52%). The median time to progression and overall survival time were 7 months (95% CI 3-10) and 11 months (95% CI 5-18), respectively. Major severe toxicities (grade 3 and 4) were: nausea/vomiting (17%), alopecia (17%); leukopenia (27%) in total cycles. Mild toxicities (grade 1 or 2) were leukopenia (73%), nausea/vomiting (83%), hepatic lesion (14%) and anemia (44%). A CTX-HCPT regimen can control disease progression effectively and the side effects can be tolerable for Chinese advanced Ewing's sarcoma patients. Further assessment is necessary to confirm the safety and efficacy of this treatment. © 2012 Wiley Publishing Asia Pty Ltd.

  14. Proceedings of the International Symposium on Advances in Nuclear Physics. Fifty Years of Institutional Physics Research in Romania

    International Nuclear Information System (INIS)

    Poenaru, Dorin; Stoica, Sabin

    2000-01-01

    This Symposium was devoted to the cerebration of 50 years of Institutional Physics Research in Romania. The inaugural talk was given by professor W. Greiner on development in fission, fusion, cluster radioactivity and the extension of the periodic system of elements. Seven divisions followed on the items: super heavy nuclei (4 talks); new fission modes (4 talks); astrophysics and cosmic rays (5 talks); particle and high energy physics (6 talks); hadronic matter (6 talks); nuclear structure and reactions (13 talks); atomic physics (4 talks); applications and history. Many of these talks highlighted the substantial Romanian contributions to the scientific achievements in these fields

  15. Drug induced xerostomia in elderly individuals: An institutional study

    Directory of Open Access Journals (Sweden)

    Shishir Ram Shetty

    2012-01-01

    Full Text Available Introduction : With better health care facilities and nutritional levels the average life expectancy of Indian population has been on the rise over the years. Most of the geriatric population is under long-term medication. Aim : The aim of this study was to evaluate the synergistic effect of multiple xerostomia drugs. Materials and Methods : Unstimulated saliva was measured in 60 geriatric patients, and xerostomia questionnaire and quality-of-life scale were also administered. Results : There was a very highly significant reduction in the salivary flow rates of patients under multiple xerostomia-inducing drugs. Conclusion : The synergistic effect of the xerostomia inducing medication could be the possible factor responsible for reduced salivary flow in elderly individuals using such drugs

  16. Cluster Policy in the Light of Institutional Context—A Comparative Study of Transition Countries

    Directory of Open Access Journals (Sweden)

    Tine Lehmann

    2015-10-01

    Full Text Available The business environment in transition countries is often extraordinarily challenging for companies. The transition process these countries find themselves in leads to constant changes in the institutional environment. Hence, institutional voids prevail. These institutional voids cause competitive disadvantages for small and medium enterprises. Cluster policy can address these competitive disadvantages. As cluster policy generally aims at supporting companies’ competitive advantage by spurring innovation and productivity, it can help to bridge institutional voids. This article’s research question aims at analyzing and comparing cluster policies in the institutional context of two transition countries (Serbia and Tunisia and analyzes to what extent cluster policies in these two countries are adapted to institutional voids prevailing there. The case studies offer insights into apparent difficulties of clusters in bridging formal institutional voids, as well as, notably, into the informal void of skill mismatches in the labor market. Still, for some specific voids, clusters do at least implicitly assume a bridging role. While the cluster policies examined do not explicitly target the institutional voids identified, cluster management can—in the course of time—align its service offering more closely with these voids. Bottom-up designed cluster policies can play an especially important role in such an evolution towards bridging institutional voids.

  17. Further assessment studies of the Advanced Cold Process Canister

    International Nuclear Information System (INIS)

    Henshaw, J.; Hoch, A.; Sharland, S.M.

    1990-08-01

    A preliminary assessment of the performance of the Advanced Cold Process Canister (ACPC) was carried out recently by Marsh. The aim of the study presented in this report is to re-examine the validity of some of the assumptions made, and re-evaluate the canister performance as appropriate. Two areas were highlighted in the preliminary study as requiring more detailed quantitative evaluation. 1) Assessment of the risk of internal stress-corrosion cracking induced by irradiation of moist air inside the canister if, under fault conditions, significant water was carried into the canister before sealing. 2) Evaluation of the corrosion behaviour subsequent to first breach of outer container. (author)

  18. Advances in molecular genetic studies of primary dystonia

    Directory of Open Access Journals (Sweden)

    MA Ling-yan

    2013-07-01

    Full Text Available Dystonias are heterogeneous hyperkinetic movement disorders characterized by involuntary muscle contractions which result in twisting, repetitive movements and abnormal postures. In recent years, there was a great advance in molecular genetic studies of primary dystonia. This paper will review the clinical characteristics and molecular genetic studies of primary dystonia, including early-onset generalized torsion dystonia (DYT1, whispering dysphonia (DYT4, dopa-responsive dystonia (DYT5, mixed-type dystonia (DYT6, paroxysmal kinesigenic dyskinesia (DYT10, myoclonus-dystonia syndrome (DYT11, rapid-onset dystonia parkinsonism (DYT12, adult-onset cervical dystonia (DYT23, craniocervical dystonia (DYT24 and primary torsion dystonia (DYT25.

  19. The advanced neutron source facility: Safety philosophy and studies

    International Nuclear Information System (INIS)

    Greene, S.R.; Harrington, R.M.

    1988-01-01

    The Advanced Neutron Source (ANS) is currently the only new civilian nuclear reactor facility proposed for construction in the United States. Even though the thermal power of this research-oriented reactor is a relatively low 300 MW, the design will undoubtedly receive intense scrutiny before construction is allowed to proceed. Safety studies are already under way to ensure that the maximum degree of safety in incorporated into the design and that the design is acceptable to the Department of Energy (DOE) and can meet the Nuclear Regulatory Commission regulations. This document discusses these safety studies

  20. System studies for quasi-steady-state advanced physics tokamak

    International Nuclear Information System (INIS)

    Reid, R.L.; Peng, Y.K.M.

    1983-11-01

    Parametric studies were conducted using the Fusion Engineering Design Center (FEDC) Tokamak Systems Code to investigate the impact of veriation in physics parameters and technology limits on the performance and cost of a low q/sub psi/, high beta, quasi-steady-state tokamak for the purpose of fusion engineering experimentation. The features and characteristics chosen from each study were embodied into a single Advanced Physics Tokamak design for which a self-consistent set of parameters was generated and a value of capital cost was estimated

  1. Is it feasible to discuss an advance directive with a Chinese patient with advanced malignancy? A prospective cohort study.

    Science.gov (United States)

    Wong, S Y; Lo, S H; Chan, C H; Chui, H S; Sze, W K; Tung, Y

    2012-06-01

    Advance directives have been implemented for years in western countries, but the concept is new to Asian cultures. According to traditional Chinese culture, family members usually play a decisive role in a patient's treatment plan. Thus it may be hard to implement an advance directive despite its importance to the treatment of patients. The objectives of this study were to assess the feasibility of advance directive engagement and to explore significant contributing factors to achieving such a goal. Prospective cohort study. Palliative Care Unit of Clinical Oncology, Tuen Mun Hospital, Hong Kong. The subjects of the investigation were adult patients diagnosed to have advanced malignancy and newly referred to the hospice service from 24 April 2009 to 30 July 2009. Data were collected from nursing assessment forms, locally designed advance directive forms, a checklist completed by oncologists, and details available in the electronic hospital record. Of the 191 eligible patients, 120 (63%) had the advance directive, whereas 71 (37%) did not. In the Cox regression model, the patient having insight of a poor prognosis was the most significant factor facilitating advance directive engagement (P=0.001). Any family objection in the discussion of advance directives was also an important factor, though it did not reach statistical significance (P=0.082). Other factors like age, gender, education, religion, financial status, living environment, understanding the diagnosis, bereavement experience, type of cancer, nature of illness, courses of chemotherapy or radiotherapy received, main caregiver, in-house supporter, nurse-led clinic attendance, clinical psychologist consultation, and in-patient hospice nurse coordinator interview were all statistically insignificant. Our study demonstrated that it was feasible to discuss an advance directive with Chinese patients with advanced malignancy. When patients have insight about their poor prognosis and family members have no

  2. Understanding institutional stakeholders’ perspectives on multidrug-resistant bacterial organism at the end of life: a qualitative study

    Directory of Open Access Journals (Sweden)

    Heckel M

    2017-10-01

    Full Text Available Maria Heckel,1 Franziska A Herbst,2 Thomas Adelhardt,3 Johanna M Tiedtke,4 Alexander Sturm,5 Stephanie Stiel,2 Christoph Ostgathe1 1Department of Palliative Medicine, Comprehensive Cancer Center Erlangen-EMN, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU, Universitätsklinikum Erlangen, Bavaria, Germany; 2Institute for General Practice, Hannover Medical School, Hannover, Germany; 3Division of Health Management, School of Business and Economics, Institute of Management (IFM, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU, Bavaria, Germany; 4Institute of Psychogerontology, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU, Bavaria, Germany; 5Department of General Internal and Geriatric Medicine, Institute for Biomedicine of Aging, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU, Hospital of the Order of St John of God Regensburg, Bavaria, Germany Background: Information lacks about institutional stakeholders’ perspectives on management approaches of multidrug-resistant bacterial organism in end-of-life situations. The term “institutional stakeholder” includes persons in leading positions with responsibility in hospitals’ multidrug-resistant bacterial organism management. They have great influence on how strategies on multidrug-resistant bacterial organism management approaches in institutions of the public health system are designed. This study targeted institutional stakeholders’ individual perspectives on multidrug-resistant bacterial organism colonization or infection and isolation measures at the end of life. Methods: Between March and December 2014, institutional stakeholders of two study centers, a German palliative care unit and a geriatric ward, were queried in semistructured interviews. Interviews were audiotaped, transcribed verbatim, and analyzed qualitatively with the aid of the software MAXQDA for qualitative data analysis using principles of Grounded Theory. In addition, two external

  3. Socio-Demographic, Reproductive and Clinical Profile of Women Diagnosed with Advanced Cervical Cancer in a Tertiary Care Institute of Delhi.

    Science.gov (United States)

    Dahiya, Neha; Bachani, Damodar; Acharya, Anita S; Sharma, D N; Gupta, Subhash; Haresh, K P

    2017-02-01

    Cervical cancer is one of the leading cancers among Indian women with estimated 123,000 new cases and 67,477 deaths in 2012. Cervical cancer is a multi-etiological disease. Factors such as low socioeconomic status, tobacco use, sexual and reproductive factors, HIV and other sexually transmitted diseases and long-term oral contraceptive use have been suggested as determinants. Assessment of socio-demographic profile and reproductive history gives a better picture of the determinants of cervical carcinoma in low-resource settings. This hospital-based cross-sectional study was undertaken at a tertiary healthcare institute at New Delhi, India. Sixty-seven newly diagnosed women with advanced cervical cancer (stage 2B-4B), who were undertaking radio- and/or chemotherapy, were included to assess their socio-demographic, reproductive and clinical profile. The mean age of women at the time of detection of cervical cancer was 52.28 ± 11.29 years (range 30-75 years). More than 60 % of patients were illiterate and belonged to middle socioeconomic status. Thirty-nine percentage of the study subjects had their first sexual experience before 15 years of age. Nearly 54 % women had 5 or more pregnancies. Nearly 73 % of women had all deliveries at home. Majority (69 %) of women had symptoms suggestive of reproductive tract infection. Among them, unusual discharge from vagina (73.13 %) followed by bleeding after menopause (55.10 %) and pain in abdomen (44.77 %) were the most common presenting complaints. Pallor was present in nearly two-third (63.93 %) study subjects. More than half (56.72 %) study subjects had moderate anemia, and 7.46 % had severe anemia before treatment. Mean hemoglobin level of the study subjects was 10.35 ± 1.72 gm% before treatment and 9.69 ± 1.29 gm% after treatment. This difference was statistically significant. Around 97 % of the study subjects had squamous cell carcinoma of the cervix. Majority (53.73 %) of the study subjects were in

  4. Is an institute for the study of high-level radioactive waste disposal needed in southern Nevada?

    International Nuclear Information System (INIS)

    Blanchard, M.B.; Robison, A.C.; Baepler, D.H.

    1993-01-01

    This paper examines key questions about the need for a formal institute that would study storage and disposal concepts for high-level radioactive waste (HLRW) in the United States and throughout the world. The questions that have been analyzed so far include: Why is an institute needed? What could this institute do to achieve the goal? How could an institute of this nature work? When could an institute form and begin functioning to meet the goals? Where could an institute be located?

  5. Neoadjuvant chemotherapy in locally advanced cervical cancer: two randomised studies

    International Nuclear Information System (INIS)

    Kumar, L.; Grover, R.; Pokharel, Y.H.; Chander, S.; Kumar, S.; Singh, R.; Rath, G.K.; Kochupillai, V.

    1998-01-01

    The results of two studies looking at the place of neo-adjuvant chemotherapy in the treatment of locally advanced cervical cancer being treated with radiotherapy are presented. Between August 1990 and January 1992, 184 patients with squamous cell carcinoma of the cervix, FIGO stage II B IVA were randomised (study 1) to receive either two cycles of bleomycin, ifosfamide-mesna and cisplatin (BIP) chemotherapy (CT) followed by radiotherapy (RT). Three patients died of CT toxicity - two in study 1 and one in study 2. Cystitis, proctitis and local skin reaction after RT occurred equally in the two groups in both the studies. The neo-adjuvant chemotherapy prior to radiotherapy demonstrated a high response rate, but this did not translate into improved overall survival compared to those patients receiving radiotherapy alone

  6. University-to-industry advanced technology transfer. A case study

    Energy Technology Data Exchange (ETDEWEB)

    Goldhor, R S; Lung, R T

    1983-06-01

    This case study examines the events in the transfer of an advanced technology (a text-to-speech reading machine) from the university group that developed the technology to an industrial firm seeking to exploit the innovation. After a brief history of the six-year project, the paper discusses the roles of the participants, markets, and time and cost considerations. A model of technology transfer is presented and policy implications derived from the case are discussed. Emphasis is placed on the need for matching technical competence between donor and recipient, and on the function of a transfer agent in facilitating the social process of technology transfer. 42 references, 6 figures, 4 tables.

  7. Creating Educational Technology Curricula for Advanced Studies in Learning Technology

    Directory of Open Access Journals (Sweden)

    Minoru Nakayama

    2016-08-01

    Full Text Available Curriculum design and content are key factors in the area of human resource development. To examine the possibility of using a collaboration of Human Computer Interaction (HCI and Educational Technology (ET to develop innovative improvements to the education system, the curricula of these two areas of study were lexically analyzed and compared. As a further example, the curriculum of a joint course in HCI and ET was also lexically analyzed and the contents were examined. These analyses can be used as references in the development of human resources for use in advanced learning environments.

  8. Mirror Advanced Reactor Study (MARS) final report summary

    International Nuclear Information System (INIS)

    Henning, C.D.; Logan, B.G.; Carlson, G.A.

    1983-01-01

    The Mirror Advanced Reactor Study (MARS) has resulted in an overview of a first-generation tandem mirror reactor. The central cell fusion plasma is self-sustained by alpha heating (ignition), while electron-cyclotron resonance heating and negative ion beams maintain the electrostatic confining potentials in the end plugs. Plug injection power is reduced by the use of high-field choke coils and thermal barriers, concepts to be tested in the Tandem Mirror Experiment-Upgrade (TMX-U) and Mirror Fusion Test Facility (MFTF-B) at Lawrence Livermore National Laboratory

  9. Study on the Application of the Prudence Principle in Accounting of Credit Institutions

    Directory of Open Access Journals (Sweden)

    Riana Iren RADU

    2014-08-01

    Full Text Available With effect from 1 January 2012, according to The NATIONAL BANK of ROMANIA No. 27/2010, International Financial reporting standards (IFRS have become the basis of the accounting system used by credit institutions in Romania. In this context, the regulatory framework relating to the adjustments for impairment of financial assets other than loans and securities is given by IAS39 and IAS 37. In this paper I propose to develop a study on the application of the prudence principle in accounting of credit institutions, a study, which will be the main issues of taxation and accounting implementation of prudent credit institutions.

  10. Determinants of organizational citizenship behavior: A case study of higher education institutes in Pakistan

    Directory of Open Access Journals (Sweden)

    Nazia Bashir

    2012-01-01

    Full Text Available This study empirically examines the relationship between altruism, conscientiousness, and civic virtue, three of the antecedents of organizational citizenship behavior, in higher education institutes in the Khyber Pakhtonkhuwa Province (KPK of Pakistan. The study is based on primary data collected from ninety-five employees of various institutes in Pakistan. The data is analyzed using the techniques of rank correlation coefficient and multiple regression analysis. All the findings are tested at 0.01 and 0.05 levels of significance. The result concludes that altruism, conscientiousness, and civic virtue have strong positive impacts on the organizational citizenship behavior in the context of higher education institutes in Pakistan.

  11. Institutional advantage

    NARCIS (Netherlands)

    Martin, Xavier

    Is there such a thing as institutional advantage—and what does it mean for the study of corporate competitive advantage? In this article, I develop the concept of institutional competitive advantage, as distinct from plain competitive advantage and from comparative institutional advantage. I first

  12. GPs' views on managing advanced chronic kidney disease in primary care: a qualitative study.

    Science.gov (United States)

    Tonkin-Crine, Sarah; Santer, Miriam; Leydon, Geraldine M; Murtagh, Fliss E M; Farrington, Ken; Caskey, Fergus; Rayner, Hugh; Roderick, Paul

    2015-07-01

    Chronic kidney disease (CKD) has become a significant part of the GP's workload since the introduction of the National Institute for Health and Care Excellence guidelines in 2008. Patients with advanced CKD (stages G4 and G5) often have comorbidities, varied disease progression, and are likely to be older. GPs may experience difficulties with management decisions for patients with advanced CKD, including when to refer to nephrology. To explore GPs' views of managing patients with advanced CKD and referral to secondary care. Qualitative study with GPs in four areas of England: London, Bristol, Birmingham, and Stevenage. Semi-structured interviews with 19 GPs. Transcribed interviews were thematically analysed. GPs had little experience of managing patients with advanced CKD, including those on dialysis or having conservative care (treatment without dialysis or a transplant), and welcomed guidance. Some GPs referred patients based on renal function alone and some used wider criteria including age and multimorbidity. GPs reported a tension between national guidance and local advice, and some had learnt from experience that patients were discharged back to primary care. GPs with more experience of managing CKD referred patients later, or sometimes not at all, if there were no additional problems and if dialysis was seen as not in the patient's interests. GPs want guidance on managing older patients with advanced CKD and comorbidities, which better incorporates agreement between local and national recommendations to clarify referral criteria. GPs are not generally aware of conservative care programmes provided by renal units, however, they appear happy to contribute to such care or alternatively, lead conservative management with input from renal teams. © British Journal of General Practice 2015.

  13. Recommendations to reduce inequalities for LGBT people facing advanced illness: ACCESSCare national qualitative interview study.

    Science.gov (United States)

    Bristowe, Katherine; Hodson, Matthew; Wee, Bee; Almack, Kathryn; Johnson, Katherine; Daveson, Barbara A; Koffman, Jonathan; McEnhill, Linda; Harding, Richard

    2018-01-01

    Lesbian, gay, bisexual and/or trans (LGBT) people have higher risk of certain life-limiting illnesses and unmet needs in advanced illness and bereavement. ACCESSCare is the first national study to examine in depth the experiences of LGBT people facing advanced illness. To explore health-care experiences of LGBT people facing advanced illness to elicit views regarding sharing identity (sexual orientation/gender history), accessing services, discrimination/exclusion and best-practice examples. Semi-structured in-depth qualitative interviews analysed using thematic analysis. In total, 40 LGBT people from across the United Kingdom facing advanced illness: cancer ( n = 21), non-cancer ( n = 16) and both a cancer and a non-cancer conditions ( n = 3). In total, five main themes emerged: (1) person-centred care needs that may require additional/different consideration for LGBT people (including different social support structures and additional legal concerns), (2) service level or interactional (created in the consultation) barriers/stressors (including heteronormative assumptions and homophobic/transphobic behaviours), (3) invisible barriers/stressors (including the historical context of pathology/criminalisation, fears and experiences of discrimination) and (4) service level or interactional facilitators (including acknowledging and including partners in critical discussions). These all shape (5) individuals' preferences for disclosing identity. Prior experiences of discrimination or violence, in response to disclosure, were carried into future care interactions and heightened with the frailty of advanced illness. Despite recent legislative change, experiences of discrimination and exclusion in health care persist for LGBT people. Ten recommendations, for health-care professionals and services/institutions, are made from the data. These are simple, low cost and offer potential gains in access to, and outcomes of, care for LGBT people.

  14. Recommendations to reduce inequalities for LGBT people facing advanced illness: ACCESSCare national qualitative interview study

    Science.gov (United States)

    Bristowe, Katherine; Hodson, Matthew; Wee, Bee; Almack, Kathryn; Johnson, Katherine; Daveson, Barbara A; Koffman, Jonathan; McEnhill, Linda; Harding, Richard

    2017-01-01

    Background: Lesbian, gay, bisexual and/or trans (LGBT) people have higher risk of certain life-limiting illnesses and unmet needs in advanced illness and bereavement. ACCESSCare is the first national study to examine in depth the experiences of LGBT people facing advanced illness. Aim: To explore health-care experiences of LGBT people facing advanced illness to elicit views regarding sharing identity (sexual orientation/gender history), accessing services, discrimination/exclusion and best-practice examples. Design: Semi-structured in-depth qualitative interviews analysed using thematic analysis. Setting/participants: In total, 40 LGBT people from across the United Kingdom facing advanced illness: cancer (n = 21), non-cancer (n = 16) and both a cancer and a non-cancer conditions (n = 3). Results: In total, five main themes emerged: (1) person-centred care needs that may require additional/different consideration for LGBT people (including different social support structures and additional legal concerns), (2) service level or interactional (created in the consultation) barriers/stressors (including heteronormative assumptions and homophobic/transphobic behaviours), (3) invisible barriers/stressors (including the historical context of pathology/criminalisation, fears and experiences of discrimination) and (4) service level or interactional facilitators (including acknowledging and including partners in critical discussions). These all shape (5) individuals’ preferences for disclosing identity. Prior experiences of discrimination or violence, in response to disclosure, were carried into future care interactions and heightened with the frailty of advanced illness. Conclusion: Despite recent legislative change, experiences of discrimination and exclusion in health care persist for LGBT people. Ten recommendations, for health-care professionals and services/institutions, are made from the data. These are simple, low cost and offer potential gains in access

  15. Advanced Fusion Power Plant Studies. Annual Report for 1999

    International Nuclear Information System (INIS)

    Chan, V.S.; Chu, M.S.; Greenfield, C.M.; Kinsey, J.E.

    2000-01-01

    Significant progress in physics understanding of the reversed shear advanced tokamak regime has been made since the last ARIES-RS study was completed in 1996. The 1999 study aimed at updating the physics design of ARIES-RS, which has been renamed ARIES-AT, using the improved understanding achieved in the last few years. The new study focused on: Improvement of beta-limit stability calculations to include important non-ideal effects such as resistive wall modes and neo-classical tearing modes; Use of physics based transport model for internal transport barrier (ITB) formation and sustainment; Comparison of current drive and rotational flow drive using fast wave, electron cyclotron wave and neutral particle beam; Improvement in heat and particle control; Integrated modeling of the optimized scenario with self-consistent current and transport profiles to study the robustness of the bootstrap alignment, ITB sustainment, and stable path to high beta and high bootstrap fraction operation

  16. Marketing within higher education institutions - A case study of two private Thai universities

    OpenAIRE

    Starck, Kristian; Zadeh, Shahriyar Hossein

    2013-01-01

    Date of final seminar: 2013-05-29. Academic level: Master Thesis in Business Administration, 15 ECTS. University: Mälardalen University, Västerås, Sweden. Institution: The School of Business, Science and Engineering. Authors: Kristian Starck and Shahriyar Hossein Zadeh. Title: Marketing within higher education institutions - A case study of two private Thai universities. Supervisor: Peter Ekman. Examiner: Eva Manninen Olsson. Purpose: The purpose of this study is to describe and analyze what ...

  17. The Premenopausal Breast Cancer Collaboration: A pooling project of studies participating in the National Cancer Institute Cohort Consortium

    Science.gov (United States)

    Nichols, Hazel B.; Schoemaker, Minouk J.; Wright, Lauren B.; McGowan, Craig; Brook, Mark N.; McClain, Kathleen M.; Jones, Michael E.; Adami, Hans-Olov; Agnoli, Claudia; Baglietto, Laura; Bernstein, Leslie; Bertrand, Kimberly A.; Blot, William J.; Boutron-Ruault, Marie-Christine; Butler, Lesley; Chen, Yu; Doody, Michele M.; Dossus, Laure; Eliassen, A. Heather; Giles, Graham G.; Gram, Inger T.; Hankinson, Susan E.; Hoffman-Bolton, Judy; Kaaks, Rudolf; Key, Timothy J.; Kirsh, Victoria A.; Kitahara, Cari M.; Koh, Woon-Puay; Larsson, Susanna C.; Lund, Eiliv; Ma, Huiyan; Merritt, Melissa A.; Milne, Roger L.; Navarro, Carmen; Overvad, Kim; Ozasa, Kotaro; Palmer, Julie R.; Peeters, Petra H.; Riboli, Elio; Rohan, Thomas E.; Sadakane, Atsuko; Sund, Malin; Tamimi, Rulla M.; Trichopoulou, Antonia; Vatten, Lars; Visvanathan, Kala; Weiderpass, Elisabete; Willett, Walter C.; Wolk, Alicja; Zeleniuch-Jacquotte, Anne; Zheng, Wei; Sandler, Dale P.; Swerdlow, Anthony J.

    2017-01-01

    Breast cancer is a leading cancer diagnosis among premenopausal women around the world. Unlike rates in postmenopausal women, incidence rates of advanced breast cancer have increased in recent decades for premenopausal women. Progress in identifying contributors to breast cancer risk among premenopausal women has been constrained by the limited numbers of premenopausal breast cancer cases in individual studies and resulting low statistical power to subcategorize exposures or to study specific subtypes. The Premenopausal Breast Cancer Collaborative Group was established to facilitate cohort-based analyses of risk factors for premenopausal breast cancer by pooling individual-level data from studies participating in the United States National Cancer Institute Cohort Consortium. This paper describes the Group, including the rationale for its initial aims related to pregnancy, obesity, and physical activity. We also describe the 20 cohort studies with data submitted to the Group by June 2016. The infrastructure developed for this work can be leveraged to support additional investigations. PMID:28600297

  18. Feasibility study of advanced operation scenario in KSTAR using CRONOS

    International Nuclear Information System (INIS)

    Kim, H.-S.; Na, Y.-S.; Bae, Y.S.; Jeon, Y.M.; Kim, S.H.; Artaud, J.-F.

    2014-01-01

    We report the results of predictive modelling of advanced operation scenarios in KSTAR. Firstly, the operation windows are produced to explore the KSTAR advanced scenarios in the condition of upgrading H/CD mix. Using METIS code, the rough ranges of operation condition of I_P and B_T to utilize for the development of advanced operation scenario scenario are determined. Secondly, the advanced inductive and the advanced tokamak operation scenario of KSTAR are developing with the scaling based and the physics based transport model by using CRONOS to make a suggestion to on-going KSTAR experiment. Thirdly, the dependency of the time of L-H transition on q_0 an q_m_i_n is investigated for the advanced inductive operation scenario. These reliable results can become the useful database for exploring the advanced regime of KSTAR discharges in the future. (author)

  19. Orthognathic Consequences of Sphincter Pharyngoplasty in Cleft Patients: A 2-Institutional Study

    Science.gov (United States)

    Yoshikane, Frances; Lai, Li Han; Hui, Brian K.; Martins, Deborah B.; Farias-Eisner, Gina; Mandelbaum, Rachel S.; Hoang, Han; Bradley, James P.; Wilson, Libby

    2016-01-01

    Background: Understanding long-term sequelae of cleft treatment is paramount in the refinement of treatment algorithms to accomplish optimized immediate and long-term outcomes. In this study, we reviewed sphincter pharyngoplasties as a method of velopharyngeal insufficiency (VPI) treatment in relationship to orthognathic surgery. Methods: Cleft lip/palate and cleft palate patients, 15 years of age and older, were reviewed for demographics, VPI surgery, revisions, and subsequent orthognathic surgery at 2 institutions. Chi-square test, Student’s t test, and logistic regression analyses were performed. Results: In 214 patients reviewed (mean age, 19.5 years), 61.7% were male, 18.2% had isolated cleft palate, 61.2% had unilateral cleft lip and palate, and 20.6% had bilateral cleft lip and palate. A total of 33.6% were diagnosed with VPI and received a sphincter pharyngoplasty (mean age, 11.9 years). When subsequent orthognathic surgery was examined, sphincter pharyngoplasty was not associated with maxillary advancement (P = 0.59) but did correlate with an increase in mandibular surgery from 2.8% to 11.1% (P = 0.02). The indications for mandibular surgery in the pharyngoplasty population were related to congenital micrognathia. When cephalometric analyses were evaluated, sphincter pharyngoplasty resulted in a decreased sella-to-nasion-to-B point angle (mean, 79.0–76.3 degrees, P = 0.02) and a higher incidence of normal to class II maxillomandibular relationships as defined by A point-to-nasion-to-B point angles >0.5 (P = 0.02). Conclusions: Sphincter pharyngoplasty decreases anterior mandibular growth and the discrepancy between maxillomandibular skeletal relationships because of the frequent predisposition of cleft patients to maxillary hypoplasia. In patients with congenital mandibular micrognathia, a small increase in mandibular surgeries may occur. PMID:27200238

  20. Establishment of an Institute for Fusion Studies. Technical progress report, 1 November 1993--31 October 1994

    International Nuclear Information System (INIS)

    Hazeltine, R.D.

    1994-07-01

    The Institute for Fusion Studies is a national center for theoretical fusion plasma physics research. Its purposes are: (1) to conduct research on theoretical questions concerning the achievement of controlled fusion energy by means of magnetic confinement--including both fundamental problems of long-range significance, as well as shorter-term issues; (2) to serve as a national and international center for information exchange by hosting exchange visits, conferences, and workshops; (3) and to train students and postdoctoral research personnel for the fusion energy program and plasma physics research areas. The theoretical research results obtained by the Institute contribute to the progress of nuclear fusion research, whose goal is the development of fusion power as a basic energy source. Close collaborative relationships have been developed with other university and national laboratory fusion groups, both in the US and abroad. In addition to its primary focus on mainstream fusion physics, the Institute is also involved with research in fusion-sidestream fields, such as advanced computing techniques, nonlinear dynamics, space plasmas and astrophysics, statistical mechanics, fluid dynamics, and accelerator physics. Important research discoveries are briefly described

  1. Design study on advanced nuclear fuel recycling system by pyrometallurgical reprocessing technology

    Energy Technology Data Exchange (ETDEWEB)

    Kasai, Yoshimitsu; Kakehi, Isao; Moro, Satoshi; Tobe, Kenji; Kawamura, Fumio; Higashi, Tatsuhiro; Yonezawa, Shigeaki [Japan Nuclear Cycle Development Inst., Oarai, Ibaraki (Japan). Oarai Engineering Center; Yoshiuji, Takahiro

    1998-12-01

    The Japan Nuclear Fuel Cycle Development Institute is conducting research and development on the nuclear fuel recycling system, which will improve the economy, safety, and environmental impact of the nuclear fuel recycling system in the age of the FBR. The System Engineering Division in the O-arai Engineering Center has conducted a design study on an advanced nuclear fuel recycling system for FBRs by using pyrometallurgical reprocessing technology. The system is an economical and compact module-type system, and can be used for reprocessing oxide fuel and also new types of fuel (metal fuel and nitride fuel). This report describes the concept of this system and results of the design study. (author)

  2. Design study on advanced nuclear fuel recycling system by pyrometallurgical reprocessing technology

    International Nuclear Information System (INIS)

    Kasai, Yoshimitsu; Kakehi, Isao; Moro, Satoshi; Tobe, Kenji; Kawamura, Fumio; Higashi, Tatsuhiro; Yonezawa, Shigeaki; Yoshiuji, Takahiro

    1998-01-01

    The Japan Nuclear Fuel Cycle Development Institute is conducting research and development on the nuclear fuel recycling system, which will improve the economy, safety, and environmental impact of the nuclear fuel recycling system in the age of the FBR. The System Engineering Division in the O-arai Engineering Center has conducted a design study on an advanced nuclear fuel recycling system for FBRs by using pyrometallurgical reprocessing technology. The system is an economical and compact module-type system, and can be used for reprocessing oxide fuel and also new types of fuel (metal fuel and nitride fuel). This report describes the concept of this system and results of the design study. (author)

  3. Evolutionary institutionalism.

    Science.gov (United States)

    Fürstenberg, Dr Kai

    Institutions are hard to define and hard to study. Long prominent in political science have been two theories: Rational Choice Institutionalism (RCI) and Historical Institutionalism (HI). Arising from the life sciences is now a third: Evolutionary Institutionalism (EI). Comparative strengths and weaknesses of these three theories warrant review, and the value-to-be-added by expanding the third beyond Darwinian evolutionary theory deserves consideration. Should evolutionary institutionalism expand to accommodate new understanding in ecology, such as might apply to the emergence of stability, and in genetics, such as might apply to political behavior? Core arguments are reviewed for each theory with more detailed exposition of the third, EI. Particular attention is paid to EI's gene-institution analogy; to variation, selection, and retention of institutional traits; to endogeneity and exogeneity; to agency and structure; and to ecosystem effects, institutional stability, and empirical limitations in behavioral genetics. RCI, HI, and EI are distinct but complementary. Institutional change, while amenable to rational-choice analysis and, retrospectively, to criticaljuncture and path-dependency analysis, is also, and importantly, ecological. Stability, like change, is an emergent property of institutions, which tend to stabilize after change in a manner analogous to allopatric speciation. EI is more than metaphorically biological in that institutional behaviors are driven by human behaviors whose evolution long preceded the appearance of institutions themselves.

  4. NRC review of Electric Power Research Institute's advanced light water reactor utility requirements document. Passive plant designs, chapter 1, project number 669

    International Nuclear Information System (INIS)

    1994-08-01

    The Electric Power Research Institute (EPRI) is preparing a compendium of technical requirements, referred to as the open-quotes Advanced Light Water Reactor [ALWR] Utility Requirements Documentclose quotes, that is acceptable to the design of an ALWR power plant. When completed, this document is intended to be a comprehensive statement of utility requirements for the design, construction, and performance of an ALWR power plant for the 1990s and beyond. The Requirements Document consists of three volumes. Volume 1, open-quotes ALWR Policy and Summary of Top-Tier Requirementsclose quotes, is a management-level synopsis of the Requirements Document, including the design objectives and philosophy, the overall physical configuration and features of a future nuclear plant design, and the steps necessary to take the proposed ALWR design criteria beyond the conceptual design state to a completed, functioning power plant. Volume II consists of 13 chapters and contains utility design requirements for an evolutionary nuclear power plant [approximately 1350 megawatts-electric (MWe)]. Volume III contains utility design requirements for nuclear plants for which passive features will be used in their designs (approximately 600 MWe). In April 1992, the staff of the Office of Nuclear Reactor Regulation, U.S. Nuclear Regulatory Commission, issued Volume 1 and Volume 2 (Parts 1 and 2) of its safety evaluation report (SER) to document the results of its review of Volumes 1 and 2 of the Requirements Document. Volume 1, open-quotes NRC Review of Electric Power Research Institute's Advanced Light Water Reactor Utility Requirements Document - Program Summaryclose quotes, provided a discussion of the overall purpose and scope of the Requirements Document, the background of the staff's review, the review approach used by the staff, and a summary of the policy and technical issues raised by the staff during its review

  5. NRC review of Electric Power Research Institute's advanced light water reactor utility requirements document. Passive plant designs, chapters 2-13, project number 669

    International Nuclear Information System (INIS)

    1994-08-01

    The Electric Power Research Institute (EPRI) is preparing a compendium of technical requirements, referred to as the open-quotes Advanced Light Water Reactor [ALWR] Utility Requirements Documentclose quotes, that is acceptable to the design of an ALWR power plant. When completed, this document is intended to be a comprehensive statement of utility requirements for the design, construction, and performance of an ALWR power plant for the 1990s and beyond. The Requirements Document consists of three volumes. Volume I, open-quotes ALWR Policy and Summary of Top-Tier Requirementsclose quotes, is a management-level synopsis of the Requirements Document, including the design objectives and philosophy, the overall physical configuration and features of a future nuclear plant design, and the steps necessary to take the proposed ALWR design criteria beyond the conceptual design state to a completed, functioning power plant. Volume II consists of 13 chapters and contains utility design requirements for an evolutionary nuclear power plant [approximately 1350 megawatts-electric (MWe)]. Volume III contains utility design requirements for nuclear plants for which passive features will be used in their designs (approximately 600 MWe). In April 1992, the staff of the Office of Nuclear Reactor Regulation, U.S. Nuclear Regulatory Commission, issued Volume 1 and Volume 2 (Parts 1 and 2) of its safety evaluation report (SER) to document the results of its review of Volumes 1 and 2 of the Requirements Document. Volume 1, open-quotes NRC Review of Electric Power Research Institute's Advanced Light Water Reactor Utility Requirements Document - Program Summaryclose quotes, provided a discussion of the overall purpose and scope of the Requirements Document, the background of the staff's review, the review approach used by the staff, and a summary of the policy and technical issues raised by the staff during its review

  6. Institutional arrangements in the emerging biodiesel industry: Case studies from Minas Gerais—Brazil

    International Nuclear Information System (INIS)

    Watanabe, Kassia; Bijman, Jos; Slingerland, Maja

    2012-01-01

    Connecting (small) family farmers to the emerging biodiesel industry requires careful design of the institutional arrangements between the producers of oil crops and the processing companies. According to institutional economics theory, the design of effective and efficient arrangements depends on production and transaction characteristics, the institutional environment, and the organizational environment supporting the transaction between producers and the industry. This paper presents a comparative study on two cases in the feedstock-for-biodiesel industry in the state of Minas Gerais, Brazil. The two case studies represent the production and transaction system of soybeans (Glycine max L. Merrill) and castor beans (Ricinus communis L.). Important elements of effective and efficient institutional arrangements are farmer collective action, availability of technical and financial support, and farmer experience with particular crops. - Highlights: ► We study institutional arrangements for feedstock transactions between family farmers and the biodiesel industry. ► We focussed on soybean and castor bean production and transaction systems. ► Institutional arrangements are affected by product and production characteristics. ► They are also affected by collective actions organizations such as cooperatives. ► Soybean involves lower transaction costs and therefore more simple arrangement than castor bean.

  7. A case study on business model innovations using Blockchain: focusing on financial institutions

    Directory of Open Access Journals (Sweden)

    JaeShup Oh

    2017-12-01

    Full Text Available Purpose - Blockchain is a distributed ledger, in which the blocks containing transaction details are connected chronologically to form a series of chains, thus raising the possibility of improving the process and innovating business model for the financial institutions. The purpose of this paper is to study the actual cases of Blockchain applied in Korea in 2017, so that a vision of business model innovation of financial institutions can be drawn. Design/methodology/approach - The financial institutions in Korea are in the technology verification stage to introduce Blockchain technology. Since there is an insufficient amount of actual measurement data, case study method was adopted. The authors interviewed ICT officers of major banks in Korea. The purpose of the interview was to understand the relationship between Blockchain and business models of financial institutions, and the effects and challenges that Blockchain has on the business model of financial institutions. Findings - From the perspective of financial institutions, the emergence of Blockchain does not just have technical significance – emergence of highly efficient database system – but has the possibility that if the business model of existing financial intermediaries disappears or get reduced, the financial services relying on them can disappear altogether, or some of them can be replaced, and financial transaction patterns of consumers can be changed. As a case studies researched for this paper, it was discovered that the distributed characteristic of Blockchain cannot be applied when actually developing financial services.

  8. An Empirical Study on Green Innovation Efficiency in the Green Institutional Environment

    Directory of Open Access Journals (Sweden)

    Yang Gao

    2018-03-01

    Full Text Available Previous studies have found that reverse technology spillover effects can promote industrial technology modernization in developing countries. However, it is still unknown whether reverse technology spillover effects can improve green innovation efficiency in developing countries. In particular, institutional uncertainties characteristic of transition economies have a significant impact on industrial modernization. Therefore, researching the impact of the institutional environment on the relationship between reverse technology spillover effects and green innovation efficiency is of great significance. In this paper, we use data from G20 countries as well as China’s foreign direct investment (FDI data to measure the effects of reverse technology spillovers and adopt the threshold effect model to explore the relationship between reverse technology spillover effects and green innovation efficiency as well as the influence of the institutional environment on this relationship, based on China’s provincial panel data from 2003 to 2015. The empirical results show that the reverse technology spillover effects can effectively improve green innovation efficiency. There is a threshold for the influence of the institutional environment on the relationship between reverse technology spillover effects and green innovation efficiency. When the institutional development level surpasses the threshold value, an acceleration effect is generated. In addition, we find that the legal system is the key bottleneck in terms of improving green innovation efficiency. How to improve and perfect the path of institutional construction in China and how to enable institutions to gain threshold speed-up effects have become the major problems the Chinese government faces in institutional construction. The research results of this paper offer a reference to developing countries in regard to improving their institutions and enhancing their green innovation efficiency.

  9. Studies of a modular advanced stellarator reactor ASRA6C

    International Nuclear Information System (INIS)

    Boehme, G.; Jentzsch, K.; Komarek, P.; Maurer, W.; El-Guebaly, L.A.; Emmert, G.A.; Kulcinski, G.L.; Larsen, E.M.; Sanatarius, J.F.; Schawan, M.E.; Scharer, J.E.; Sviatoslavski, I.N.; Vogelsang, W.F.; Walstrom, P.L.; Wittenberg, L.J.; Grieger, G.; Harmeyer, E.; Herrnegger, F.; Kisslinger, J.; Rau, F.; Wobig, H.

    1987-05-01

    This study is directed towards the clarification of critical issues of advanced modular stellerator reactors exploiting the inherent potential of steady state operation, and is not a point design study of a reactor. Critical technology issues arise from the three-dimensional magnetic field structure. The first wall, blanket and shield are more complex than those of axi-symmetric systems, but this is eased at moderate to large aspect ratio typical of stellerators. Several blanket options have been studied and a thin blanket (21 cm) was the first choice for the design. Superconducting modular coils were investigated with respect to the conductor and mechanical supports. From the analysis of forces and stresses caused by the electromagnetic loads the coils are considered to be feasible, although shear stresses might pose a critical issue. Demountable intermagnetic support elements were designed for use at separation areas between the cryostat modules. A scheme for remote reactor maintenance was also developed. The plasma physics issues of different configurations were studied using extrapolations of transort behaviour and equilibrium from theory and present experiments. These studies indicate that the confinement and equilibrium behaviour is adequate for ignited operation at an average value of 5% beta. Impurities may pose a critical issue. Several impurity control operations were investigated; a pumped limiter configuration utilizing the 'ergodic layer' at the plasma edge was chosen for edge plasma and impurity control. A general conclusion of the study is that the modular stellerator configuration offers interesting prospects regarding the development towards steady-state reactors. (orig.)

  10. Studies of a modular advanced stellarator reactor ASRA6C

    International Nuclear Information System (INIS)

    Boehme, G.; El-Guebaly, L.A.; Emmert, G.A.; Grieger, G.; Harmeyer, E.; Herrnegger, F.; Huebener, J.; Jentzsch, K.; Kisslinger, J.; Komarek, P.; Kulcinski, G.L.; Larsen, E.M.; Maurer, W.; Rau, F.; Santarius, J.F.; Sawan, M.E.; Scharer, J.E.; Sviatoslavsky, I.N.; Vogelsang, W.F.; Walstrom, P.L.; Wittenberg, L.J.; Wobig, H.

    1987-06-01

    This study is directed towards the clarification of critical issues of advanced modular stellerator reactors exploiting the inherent potential of steady state operation, and is not a point design study of a reactor. Critical technology issues arise from the three-dimensional magnetic field structure. The first wall, blanket and shield are more complex than those of axi-symmetric systems, but this is eased at moderate to large aspect ratio typical of stellarators. Several blanket options have been studied and a thin blanket (21 cm) was the first choice for the design. Superconducting modular coils were investigated with respect to the conductor and mechanical supports. From the analysis of forces and stresses caused by the electromagnetic loads the coils are considered to be feasible, although shear stresses might pose a critical issue. Demountable intermagnetic support elements were designed for use at separation areas between the cryostat modules. A scheme for remote reactor maintenance was also developed. The plasma physics issues of different configurations were studied using extrapolations of transport behaviour and equilibrium from theory and present experiments. These studies indicate that the confinement and equilibrium behaviour is adequate for ignited operation at an average value of 5% beta. Impurities may pose a critical issue. Several impurity control operations were investigated; a pumped limiter configuration utilizing the 'ergodic layer' at the plasma edge was chosen for edge plasma and impurity control. A general conclusion of the study is that the modular stellerator configuration offers interesting prospects regarding the development towards steady-state reactors. (orig.) [de

  11. Experimental study on reflooding in advanced tight lattice PWR

    International Nuclear Information System (INIS)

    Hori, K.; Kodama, J.; Teramae, T.

    2000-01-01

    This paper is related to the experimental study on the feasibility of core cooling by re-flooding in a large break loss of coolant accident (LOCA) for the advanced tight lattice pressurized water reactor (PWR). The tight lattice core design should be adopted to improve the conversion ratio. Major one of the key questions of such tight lattice core is the cooling capability under the re-flood condition in a large break LOCA. Forced feed bottom re-flooding experiments have been performed by use of a 4x4 triangular array rod bundle. The rod gap is 0.5 mm, 1.0 mm, or 1.5 mm. The measured peak temperature is below around 1273 K even in case of 1.0/0.5 mm rod gap. And, the evaluation based on the experimental results of rod temperatures and core pressure drop also shows that the core cooling under re-flooding condition is feasible. (author)

  12. Study of nanoscale structural biology using advanced particle beam microscopy

    Science.gov (United States)

    Boseman, Adam J.

    This work investigates developmental and structural biology at the nanoscale using current advancements in particle beam microscopy. Typically the examination of micro- and nanoscale features is performed using scanning electron microscopy (SEM), but in order to decrease surface charging, and increase resolution, an obscuring conductive layer is applied to the sample surface. As magnification increases, this layer begins to limit the ability to identify nanoscale surface structures. A new technology, Helium Ion Microscopy (HIM), is used to examine uncoated surface structures on the cuticle of wild type and mutant fruit flies. Corneal nanostructures observed with HIM are further investigated by FIB/SEM to provide detailed three dimensional information about internal events occurring during early structural development. These techniques are also used to reconstruct a mosquito germarium in order to characterize unknown events in early oogenesis. Findings from these studies, and many more like them, will soon unravel many of the mysteries surrounding the world of developmental biology.

  13. Treatment of Advanced Malignant Uterine Perivascular Epithelioid Cell Tumor with mTOR Inhibitors: Single-institution Experience and Review of the Literature.

    Science.gov (United States)

    Starbuck, Kristen D; Drake, Richard D; Budd, G Thomas; Rose, Peter G

    2016-11-01

    Uterine perivascular epithelioid cell tumors (PEComas) are rare mesenchymal tumors. Many have malignant behavior, and no successful treatment strategy has been established. Identification of mutations in the tuberous sclerosis 1 (TSC1) and TSC2 genes producing constitutive activation of the mammalian target of rapamycin (mTOR) pathway presents an opportunity for targeted therapy. Patients with advanced malignant uterine PEComa treated with mTOR inhibitors were identified and records were retrospectively reviewed for treatment response based on radiographic assessment. Three patients with advanced uterine PEComas underwent debulking surgery followed by mTOR inhibitor therapy; two had a complete response to therapy and disease in one patient progressed. Given the absence of effective therapies for malignant uterine PEComas, targeting the mTOR pathway is a logical strategy to pursue given the known pathobiology involving the Tuberous Sclerosis complex. Treatment of malignant uterine PEComas with mTOR inhibitors was effective in two out of three patients after surgical resection, with durable response. Copyright© 2016 International Institute of Anticancer Research (Dr. John G. Delinassios), All rights reserved.

  14. a History of Funding for WOMEN’S Programs at the National Science Foundation: from Individual Powre Approaches to the Advance of Institutional Approaches

    Science.gov (United States)

    Rosser, Sue V.; Lane, Eliesh O'neil

    The biennial reports on women, minorities, and persons with disabilities produced by the National Science Foundation (NSF) because of congressional mandate laid the statistical foundation for NSF initiatives to redress the underrepresentation of these groups. Programs established in the 1980s such as Research Opportunities for Women, Visiting Professorships for Women, Graduate Fellowships for Women, and Career Advancement Awards provided support to individual women for their research. In the 1990s, the NSF also began to focus on systemic initiatives, creating the Program for Women and Girls, although it continued to address the problem through support of individual researchers in the newly created Professional Opportunities for Women in Research and Education (POWRE) initiative. The responses from more than 400 awardees during the 4 years of POWRE provide insights into the current issues these women perceive surrounding their grants, funding, and interactions with NSF bureaucracy and staff members. The results of the POWRE survey support the institutional, systemic thrust of the NSF’s new ADVANCE initiative to attempt to solve problems such as balancing career and family that cannot be addressed solely by supporting research projects of individual female scientists and engineers.

  15. Accelerating Scientific Advancement for Pediatric Rare Lung Disease Research. Report from a National Institutes of Health-NHLBI Workshop, September 3 and 4, 2015.

    Science.gov (United States)

    Young, Lisa R; Trapnell, Bruce C; Mandl, Kenneth D; Swarr, Daniel T; Wambach, Jennifer A; Blaisdell, Carol J

    2016-12-01

    Pediatric rare lung disease (PRLD) is a term that refers to a heterogeneous group of rare disorders in children. In recent years, this field has experienced significant progress marked by scientific discoveries, multicenter and interdisciplinary collaborations, and efforts of patient advocates. Although genetic mechanisms underlie many PRLDs, pathogenesis remains uncertain for many of these disorders. Furthermore, epidemiology and natural history are insufficiently defined, and therapies are limited. To develop strategies to accelerate scientific advancement for PRLD research, the NHLBI of the National Institutes of Health convened a strategic planning workshop on September 3 and 4, 2015. The workshop brought together a group of scientific experts, intramural and extramural investigators, and advocacy groups with the following objectives: (1) to discuss the current state of PRLD research; (2) to identify scientific gaps and barriers to increasing research and improving outcomes for PRLDs; (3) to identify technologies, tools, and reagents that could be leveraged to accelerate advancement of research in this field; and (4) to develop priorities for research aimed at improving patient outcomes and quality of life. This report summarizes the workshop discussion and provides specific recommendations to guide future research in PRLD.

  16. Study on Measurement of Advanced Manufacturing: Case by China

    Directory of Open Access Journals (Sweden)

    She Jinghuai

    2017-01-01

    Full Text Available This article has built a system of China's Advanced Manufacturing measurement indicators. By applying the datum from 2004 to 2013, we estimate the level of development and current status of China’s Advanced Manufacturing (AM, and evaluate the measurement results by establishing Hierarchical Linear Model (HLM. We confirmed that China's Advanced Manufacturing is in the rapid development trend. And due to the difference of initial conditions in Advanced Manufacturing development there is a greater imbalance. In contrast, a region with poor initial condition of has a relatively fast development speed.

  17. Ethnic, Women's, and African American Studies Majors in U.S. Institutions of Higher Education

    Science.gov (United States)

    Olzak, Susan; Kangas, Nicole

    2008-01-01

    African American Studies, Ethnic Studies, and Women's Studies programs in higher education have received wide support from faculty members and students, yet few programs offer a major or have tenure-line faculty positions. Our analysis used sociological theories to generate testable implications about the chances that an institution will offer…

  18. Advanced methods for the study of PWR cores

    International Nuclear Information System (INIS)

    Lambert, M.; Salvatores, St.; Ferrier, A.; Pelet, J.; Nicaise, N.; Pouliquen, J.Y.; Foret, F.; Chauliac, C.; Johner, J.; Cohen, Ch.

    2003-01-01

    This document gathers the transparencies presented at the 6. technical session of the French nuclear energy society (SFEN) in October 2003. The transparencies of the annual meeting are presented in the introductive part: 1 - status of the French nuclear park: nuclear energy results, management of an exceptional climatic situation: the heat wave of summer 2003 and the power generation (J.C. Barral); 2 - status of the research on controlled thermonuclear fusion (J. Johner). Then follows the technical session about the advanced methods for the study of PWR reactor cores: 1 - the evolution approach of study methodologies (M. Lambert, J. Pelet); 2 - the point of view of the nuclear safety authority (D. Brenot); 3 - the improved decoupled methodology for the steam pipe rupture (S. Salvatores, J.Y. Pouliquen); 4 - the MIR method for the pellet-clad interaction (renovated IPG methodology) (E. Baud, C. Royere); 5 - the improved fuel management (IFM) studies for Koeberg (C. Cohen); 6 - principle of the methods of accident study implemented for the European pressurized reactor (EPR) (F. Foret, A. Ferrier); 7 - accident studies with the EPR, steam pipe rupture (N. Nicaise, S. Salvatores); 8 - the co-development platform, a new generation of software tools for the new methodologies (C. Chauliac). (J.S.)

  19. NATO Advanced Study Institute on the Physics of Structurally Disordered Solids

    CERN Document Server

    1976-01-01

    Structurally disordered solids are characterized by their lack of spatial order that is evidenced by the great variety of ordered solids. The former class of materials is commonly termed amorphous or glassy, the latter crystalline. However, both classes share, many of the other physical properties of solids, e. g. , me­ chanical stability, resistance to shear stress, etc. The traditional macroscopic distinction between the crystalline and the glassy states is that while the former has a fixed melting point, the latter does not. However, with the availability and production of a large number of materials in both crystalline and amorphous states, and their easy inter-convertability, simple de­ finitions are not possible or at best imprecise. For the present purpose, it is sufficient to say that in contrast to the crystalline state, in which the posi­ tions of atoms are fixed into adefinite structure, ex­ cept for small thermal vibrations, the amorphous state of the same material displays varying degrees of ...

  20. Scientific Affairs Division of NATO Advanced Study Institute: abstracts for nonequilibrium superconductivity, phonons and Kapitza boundaries

    International Nuclear Information System (INIS)

    1980-05-01

    Abstracts of papers presented at the meeting are given. Topics covered include: Kapitza resistance; superconducting tunneling; energy gap enhancement in superconductors; instabilities in nonequilibrium superconducting states; exchange of charge between superconducting pairs and quasiparticles; motion of magnetic flux (flux flow); and other new phenomena

  1. Radiotherapy and Brachytherapy : Proceedings of the NATO Advanced Study Institute on Physics of Modern Radiotherapy & Brachytherapy

    CERN Document Server

    Lemoigne, Yves

    2009-01-01

    This volume collects a series of lectures presented at the tenth ESI School held at Archamps (FR) in November 2007 and dedicated to radiotherapy and brachytherapy. The lectures focus on the multiple facets of radiotherapy in general, including external radiotherapy (often called teletherapy) as well as internal radiotherapy (called brachytherapy). Radiotherapy strategy and dose management as well as the decisive role of digital imaging in the associated clinical practice are developed in several articles. Grouped under the discipline of Conformal Radiotherapy (CRT), numerous modern techniques, from Multi-Leaf Collimators (MLC) to Intensity Modulated RadioTherapy (IMRT), are explained in detail. The importance of treatment planning based upon patient data from digital imaging (Computed Tomography) is also underlined. Finally, despite the quasi- totality of patients being presently treated with gamma and X-rays, novel powerful tools are emerging using proton and light ions (like carbon ions) beams, bound to bec...

  2. New nuclear data libraries available from the Aerospace Technical Center - Institute for Advanced Studies

    International Nuclear Information System (INIS)

    Moraes Cunha, M. de; Corcuera, R.P.

    1993-03-01

    The new nuclear data libraries available at IEAv are described. Information about contents, length, format and bibliographic references of the nuclear data compiled in these libraries are given. (author)

  3. NATO Advanced Study Institute on Materials Issues for Generation IV Systems : Status, Open Questions and Challenges

    CERN Document Server

    Gorse, Dominique; Mazière, Dominique; Pontikis, Vassilis

    2008-01-01

    Global warming, shortage of low-cost oil resources and the increasing demand for energy are currently controlling the world's economic expansion while often opposing desires for sustainable and peaceful development. In this context, atomic energy satisfactorily fulfills the criteria of low carbon gas production and high overall yield. However, in the absence of industrial fast-breeders the use of nuclear fuel is not optimal, and the production of high activity waste materials is at a maximum. These are the principal reasons for the development of a new, fourth generation of nuclear reactors, minimizing the undesirable side-effects of current nuclear energy production technology while increasing yields by increasing operation temperatures and opening the way for the industrial production of hydrogen through the decomposition of water. The construction and use of such reactors is hindered by several factors, including performance limitations of known structural materials, particularly if the life of the project...

  4. NATO Advanced Study Institute entitled Physics of Plasma-Wall Interactions in Controlled Fusion

    CERN Document Server

    Behrisch, R; Physics of plasma-wall interactions in controlled fusion

    1986-01-01

    Controlled thermonuclear fusion is one of the possible candidates for long term energy sources which will be indispensable for our highly technological society. However, the physics and technology of controlled fusion are extremely complex and still require a great deal of research and development before fusion can be a practical energy source. For producing energy via controlled fusion a deuterium-tritium gas has to be heated to temperatures of a few 100 Million °c corres­ ponding to about 10 keV. For net energy gain, this hot plasma has to be confined at a certain density for a certain time One pro­ mising scheme to confine such a plasma is the use of i~tense mag­ netic fields. However, the plasma diffuses out of the confining magnetic surfaces and impinges on the surrounding vessel walls which isolate the plasma from the surrounding air. Because of this plasma wall interaction, particles from the plasma are lost to the walls by implantation and are partially reemitted into the plasma. In addition, wall...

  5. NATO Advanced Study Institute on Hydrogen in Disordered and Amorphous Solids

    CERN Document Server

    Bowman, Robert

    1986-01-01

    This is the second volume in the NATO ASI series dealing with the topic of hydrogen in solids. The first (V. B76, Metal Hydrides) appeared five years ago and focussed primarily on crystalline phases of hydrided metallic systems. In the intervening period, the amorphous solid state has become an area of intense research activity, encompassing both metallic and non-metallic, e.g. semiconducting, systems. At the same time the problem of storage of hydrogen, which motivated the first ASI, continues to be important. In the case of metallic systems, there were early indications that metallic glasses and disordered alloys may be more corrosion resistant, less susceptible to embrittlement by hydrogen and have a higher hydrogen mobility than ordered metals or intermetallics. All of these properties are desirable for hydrogen storage. Subsequent research has shown that thermodynamic instability is a severe problem in many amorphous metal hydrides. The present ASI has provided an appropriate forum to focus on these issu...

  6. NATO Advanced Study Institute on Sprites, Elves and Intense Lightning Discharges

    CERN Document Server

    Füllekrug, Martin; Rycroft, Michael J

    2006-01-01

    Particularly intense lightning discharges can produce transient luminous events above thunderclouds, termed sprites, elves and jets. These short lived optical emissions in the mesosphere can reach from the tops of thunderclouds up to the ionosphere; they provide direct evidence of coupling from the lower atmosphere to the upper atmosphere. Sprites are arguably the most dramatic recent discovery in solar-terrestrial physics. Shortly after the first ground based video recordings of sprites, observations on board the Space Shuttle detected sprites and elves occurring all around the world. These reports led to detailed sprite observations in North America, South America, Australia, Japan, and Europe. Subsequently, sprites were detected from other space platforms such as the International Space Station and the ROCSAT satellite. During the past 15 years, more than 200 contributions on sprites have been published in the scientific literature to document this rapidly evolving new research area.

  7. NATO Advanced Study Institute: Marie Curie Training Course: Applications of Random Matrices in Physics

    CERN Document Server

    Kazakov, Vladimir; Serban, Didina; Wiegmann, Paul; Zabrodin, Anton

    2006-01-01

    Random matrices are widely and successfully used in physics for almost 60-70 years, beginning with the works of Dyson and Wigner. Although it is an old subject, it is constantly developing into new areas of physics and mathematics. It constitutes now a part of the general culture of a theoretical physicist. Mathematical methods inspired by random matrix theory become more powerful, sophisticated and enjoy rapidly growing applications in physics. Recent examples include the calculation of universal correlations in the mesoscopic system, new applications in disordered and quantum chaotic systems, in combinatorial and growth models, as well as the recent breakthrough, due to the matrix models, in two dimensional gravity and string theory and the non-abelian gauge theories. The book consists of the lectures of the leading specialists and covers rather systematically many of these topics. It can be useful to the specialists in various subjects using random matrices, from PhD students to confirmed scientists.

  8. NATO Advanced Study Institute on Evolution from Cellular to Social Scales

    CERN Document Server

    Skjeltorp, Arne T

    2008-01-01

    Evolution is a critical challenge for many areas of science, technology and development of society. The book reviews general evolutionary facts such as origin of life and evolution of the genome and clues to evolution through simple systems. Emerging areas of science such as "systems biology" and "bio-complexity" are founded on the idea that phenomena need to be understood in the context of highly interactive processes operating at different levels and on different scales. This is where physics meets complexity in nature, and where we must begin to learn about complexity if we are to understand it. Similarly, there is an increasingly urgent need to understand and predict the evolutionary behavior of highly interacting man-made systems, in areas such as communications and transport, which permeate the modern world. The same applies to the evolution of human networks such as social, political and financial systems, where technology has tended to vastly increase both the complexity and speed of interaction, whic...

  9. NATO Advanced Study Institute on Scanning Probe Microscopy : Characterization, Nanofabrication and Device Application of Functional Materials

    CERN Document Server

    Vilarinho, Paula Maria; Kingon, Angus; Scanning Probe Microscopy : Characterization, Nanofabrication and Device Application of Functional Materials

    2005-01-01

    As the characteristic dimensions of electronic devices continue to shrink, the ability to characterize their electronic properties at the nanometer scale has come to be of outstanding importance. In this sense, Scanning Probe Microscopy (SPM) is becoming an indispensable tool, playing a key role in nanoscience and nanotechnology. SPM is opening new opportunities to measure semiconductor electronic properties with unprecedented spatial resolution. SPM is being successfully applied for nanoscale characterization of ferroelectric thin films. In the area of functional molecular materials it is being used as a probe to contact molecular structures in order to characterize their electrical properties, as a manipulator to assemble nanoparticles and nanotubes into simple devices, and as a tool to pattern molecular nanostructures. This book provides in-depth information on new and emerging applications of SPM to the field of materials science, namely in the areas of characterisation, device application and nanofabrica...

  10. NATO Advanced Study Institute on Biophysics and Structure to Counter Threats and Challenges

    CERN Document Server

    Margaris, Manolia

    2013-01-01

    This ASI brought together a diverse group of experts who span virology, biology, biophysics, chemistry, physics and engineering.  Prominent lecturers representing world renowned scientists from nine (9) different countries, and students from around the world representing eighteen (18) countries, participated in the ASI organized by Professors Joseph Puglisi (Stanford University, USA) and Alexander Arseniev (Moscow, RU).   The central hypothesis underlying this ASI was that interdisciplinary research, merging principles of physics, chemistry and biology, can drive new discovery in detecting and fighting chemical and bioterrorism agents, lead to cleaner environments and improved energy sources, and help propel development in NATO partner countries.  At the end of the ASI students had an appreciation of how to apply each technique to their own particular research problem and to demonstrate that multifaceted approaches and new technologies are needed to solve the biological challenges of our time.  The course...

  11. NATO Advanced Study Institute on Remote Sensing Applications in Marine Science and Technology

    CERN Document Server

    1983-01-01

    This summer school was a sequel to the summer school on Remote Sensing in Meteorology, Oceanography and Hydrology which was held in Dundee in 1980 and the proceedings of which were published by Ellis Horwood Ltd., Chichester, England. At the present summer scnool we concentrated on only part of the subject area that was covered in 1980. Although there was some repetit­ ion of material that was presented in 1980, because by and large we had a new set of participants, most subjects were treated in considerably greater detail than had been possible previously. The major topics covered in the present summer school were (i) the general principles of remote sensing with particular reference to marine applications, (ii) applications to physical oceanography, (iii) marine resources applications and (iv) coastal monitoring and protection. The material contained in this volume represents the written texts of most of the lectures presented at the summer school. One important set of lecture notes was not available; this...

  12. Feasibility study on the development of advanced LWR fuel technology

    International Nuclear Information System (INIS)

    Jung, Youn Ho; Sohn, D. S.; Jeong, Y. H.; Song, K. W.; Song, K. N.; Chun, T. H.; Bang, J. G.; Bae, K. K.; Kim, D. H. and others.

    1997-07-01

    Worldwide R and D trends related to core technology of LWR fuels and status of patents have been surveyed for the feasibility study. In addition, various fuel cycle schemes have been studied to establish the target performance parameters. For the development of cladding material, establishment of long-term research plan for alloy development and optimization of melting process and manufacturing technology were conducted. A work which could characterize the effect of sintering additives on the microstructure of UO 2 pellet has been experimentally undertaken, and major sintering variables and their ranges have been found in the sintering process of UO 2 -Gd 2 O 3 burnable absorber pellet. The analysis of state of the art technology related to flow mixing device for spacer grid and debris filtering device for bottom nozzle and the investigation of the physical phenomena related to CHF enhancement and the establishment of the data base for thermal-hydraulic performance tests has been done in this study. In addition, survey on the documents of the up-to-date PWR fuel assemblies developed by foreign vendors have been carried out to understand their R and D trends and establish the direction of R and D for these structural components. And, to set the performance target of the new fuel, to be developed, fuel burnup and economy under the extended fuel cycle length scheme were estimated. A preliminary study on the failure mechanism of CANDU fuel, key technology and advanced coating has been performed. (author). 190 refs., 31 tabs., 129 figs

  13. A study of reset mode in advanced alarm system simulator

    International Nuclear Information System (INIS)

    Yenn, T. C.; Hwang, S. L.; Huang, F. H.; Yu, A. C.; Hsu, C. C.; Huang, H. W.

    2006-01-01

    An automation function has been widely applied in main control room of nuclear power plants. That leads to a new issue of human-automation interaction, which considers human operational performance in automated systems. In this research is the automation alarm reset in the advanced alarm system (AAS) of Advanced Nuclear Power Plant in Taiwan. Since alarms are very crucial for the understanding of the status of the plant as well as the reset function of alarm system will be changed from fully manual to fully automatic, it is very important to test and evaluate the performance and the effect of reset modes in AAS. The purpose of this paper is to evaluate the impact of the auto-reset alarm system on the plant performance and on operators' preference and task load. To develop a dynamic simulator as an AAS was conducted to compare manual and automatic reset function of alarm system on task performance and subjective ratings of task workload, comprehension, and preference. The simulation includes PCTRAN model and alarm software processing. The final results revealed that, using the auto-reset mode, participants had lower task load index (TLX) on effort in the first test trial and was more satisfied in multiple tasks condition. In contrast, using manual reset mode, participants were more satisfied on alarm handling, monitoring, and decision making. In other words, either reset mode in the study has unique features to assist operator, but is insufficient. The reset function in AAS therefore should be very flexible. Additionally, the experimental results also pointed out that the user interfaces need to be improved. Those experiences will be helpful for human factors verification and validation in the near future. (authors)

  14. Medical student storytelling on an institutional blog: a case study analysis.

    Science.gov (United States)

    Becker, Katherine A; Freberg, Karen

    2014-05-01

    Despite the proclivity and proliferation of blogs on the Internet, the use of blogs at medical institutions is not well documented. In examining the structured stories that medical students share with the digital community, we may better understand how students use institutional blogs to discuss their medical school experiences while maintaining their role as a medical student ambassador for the program. We conducted a case study to analyze the stories within 309 medical student blogs from one medical institution in the United States. In an attempt to communicate their experiences to different benefactors, student bloggers engaged in structured and personal storytelling. Structured stories offered medical school advice to prospective students, while personal stories embodied features of a personal diary where students recounted significant milestones, talked about personal relationships and engaged in emotional reflection and disclosure. Institutional blogs may provide social marketing for medical institutions, as students strategically framed their experiences to reflect a positive attitude about the medical institution and focused on providing advice to prospective students. Although these structured stories limit complete disclosure, students may still achieve benefits by engaging in emotional disclosure and personal reflection.

  15. Advanced control of a water supply system : A case study

    NARCIS (Netherlands)

    Bakker, M.; Rajewicz, T.; Kien, H.; Vreeburg, J.H.G.; Rietveld, L.C.

    2013-01-01

    WTP Gruszczyn supplies drinking water to a part of the city of Pozna?, in the Midwest of Poland. The conventional production flow control and pressure control of the facility was replaced by the advanced control software called OPIR. To assess the differences between conventional and advanced

  16. A Case Study of an Internationalization Process of a Private Higher Education Institution in Malaysia

    Directory of Open Access Journals (Sweden)

    Abu Bakar Abdul Rahim

    2013-12-01

    Full Text Available The increasing competition and commercialization of higher education has led to the internationalization of Higher Education Institutions (HEIs around the world. While internationalization appears to be inevitable, differences are apparent in its definitions, depth, scope and mode. The main aim of this paper is to assess the internationalization efforts of Malaysian HEIs through a case study on the internationalization process of one private HEI. The case highlights various weaknesses of the internationalization effort in the institution. The symptoms and the causes of the problems in the institution corroborate similar findings in other studies involving the internationalization of HEIs. Suggestions and recommendations are presented to enable other organizations that wish to undertake similar internationalization efforts to learn from the case study institution’s experience.

  17. Advance study of fiber-reinforced self-compacting concrete

    Science.gov (United States)

    Mironova, M.; Ivanova, M.; Naidenov, V.; Georgiev, I.; Stary, J.

    2015-10-01

    Incorporation in concrete composition of steel macro- and micro - fiber reinforcement with structural function increases the degree of ductility of typically brittle cement-containing composites, which in some cases can replace completely or partially conventional steel reinforcement in the form of rods and meshes. Thus, that can reduce manufacturing, detailing and placement of conventional reinforcement, which enhances productivity and economic efficiency of the building process. In this paper, six fiber-reinforced with different amounts of steel fiber cement-containing self-compacting compositions are investigated. The results of some of their main strength-deformation characteristics are presented. Advance approach for the study of structural and material properties of these type composites is proposed by using the methods of industrial computed tomography. The obtained original tomography results about the microstructure and characteristics of individual structural components make it possible to analyze the effective macro-characteristics of the studied composites. The resulting analytical data are relevant for the purposes of multi-dimensional modeling of these systems. Multifactor structure-mechanical analysis of the obtained with different methods original scientific results is proposed. It is presented a conclusion of the capabilities and effectiveness of complex analysis in the studies to characterize the properties of self-compacting fiber-reinforced concrete.

  18. Advance study of fiber-reinforced self-compacting concrete

    International Nuclear Information System (INIS)

    Mironova, M.; Ivanova, M.; Naidenov, V.; Georgiev, I.; Stary, J.

    2015-01-01

    Incorporation in concrete composition of steel macro- and micro – fiber reinforcement with structural function increases the degree of ductility of typically brittle cement-containing composites, which in some cases can replace completely or partially conventional steel reinforcement in the form of rods and meshes. Thus, that can reduce manufacturing, detailing and placement of conventional reinforcement, which enhances productivity and economic efficiency of the building process. In this paper, six fiber-reinforced with different amounts of steel fiber cement-containing self-compacting compositions are investigated. The results of some of their main strength-deformation characteristics are presented. Advance approach for the study of structural and material properties of these type composites is proposed by using the methods of industrial computed tomography. The obtained original tomography results about the microstructure and characteristics of individual structural components make it possible to analyze the effective macro-characteristics of the studied composites. The resulting analytical data are relevant for the purposes of multi-dimensional modeling of these systems. Multifactor structure-mechanical analysis of the obtained with different methods original scientific results is proposed. It is presented a conclusion of the capabilities and effectiveness of complex analysis in the studies to characterize the properties of self-compacting fiber-reinforced concrete

  19. Advance study of fiber-reinforced self-compacting concrete

    Energy Technology Data Exchange (ETDEWEB)

    Mironova, M., E-mail: mirona@imbm.bas.bg; Ivanova, M., E-mail: magdalena.ivanova@imbm.bas.bg; Naidenov, V., E-mail: valna53@mail.bg [Institute of Mechanics, Bulgarian Academy of Sciences, Acad. G. Bonchev str., bl. 4, Sofia 1113 (Bulgaria); Georgiev, I., E-mail: ivan.georgiev@parallel.bas.bg [Institute of Information and Communication Technologies & Institute of Mathematics and Informatics, Bulgarian Academy of Sciences, Acad. G. Bonchev str., Sofia 1113 (Bulgaria); Stary, J., E-mail: stary@ugn.cas.cz [Institute of Geonics Czech Academy of Sciences, Studentska str., Ostrava 1768 (Czech Republic)

    2015-10-28

    Incorporation in concrete composition of steel macro- and micro – fiber reinforcement with structural function increases the degree of ductility of typically brittle cement-containing composites, which in some cases can replace completely or partially conventional steel reinforcement in the form of rods and meshes. Thus, that can reduce manufacturing, detailing and placement of conventional reinforcement, which enhances productivity and economic efficiency of the building process. In this paper, six fiber-reinforced with different amounts of steel fiber cement-containing self-compacting compositions are investigated. The results of some of their main strength-deformation characteristics are presented. Advance approach for the study of structural and material properties of these type composites is proposed by using the methods of industrial computed tomography. The obtained original tomography results about the microstructure and characteristics of individual structural components make it possible to analyze the effective macro-characteristics of the studied composites. The resulting analytical data are relevant for the purposes of multi-dimensional modeling of these systems. Multifactor structure-mechanical analysis of the obtained with different methods original scientific results is proposed. It is presented a conclusion of the capabilities and effectiveness of complex analysis in the studies to characterize the properties of self-compacting fiber-reinforced concrete.

  20. Advanced Orofacial Rhabdomyosarcoma: A Retrospective Study of 31 Cases

    Directory of Open Access Journals (Sweden)

    Otmani, Naima

    2016-02-01

    Full Text Available Introduction Rhabdomyosarcoma (RMS is the most common soft tissue sarcoma encountered in childhood and adolescence. Early diagnosis of pediatric cases is critical to improving outcomes, especially when socioeconomic status and geographical access to specialist services can reduce opportunities for early cancer detection and treatment. Objective The objective of this study is to determine factors that can delay referral and treatment in specialist pediatric oncology center upon our population specificities. Methods This retrospective study involved 31 children between 2003 and 2013. Children affected by histologically confirmed RMS occurring as a primary lesion in the orofacial area were included. Results The median age was 8 ± 4.22 years (range: 3 months – 15 years. The male to female ratio was 1.8:1. Most of the patients had advanced stage disease at presentation (81.7% group had 3–4 pretreatment staging with parameningeal involvement in 80.6% of the cases. The 2-year event-free survival rate was 17.7 ± 7.8% for all the patients. Delay of admission to our unit and abandonment of treatment seem to be important factors for the dismal prognosis. Conclusion Patient's location, socioeconomic status and health care coverage have had an impact on longer delays in seeking care and on follow-up. More studies are needed for implementation of a better management practices and a better supportive care upon specificities of our population.

  1. Advanced Orofacial Rhabdomyosarcoma: A Retrospective Study of 31 Cases.

    Science.gov (United States)

    Otmani, Naima; Khattab, Mohamed

    2016-07-01

    Rhabdomyosarcoma (RMS) is the most common soft tissue sarcoma encountered in childhood and adolescence. Early diagnosis of pediatric cases is critical to improving outcomes, especially when socioeconomic status and geographical access to specialist services can reduce opportunities for early cancer detection and treatment. The objective of this study is to determine factors that can delay referral and treatment in specialist pediatric oncology center upon our population specificities. This retrospective study involved 31 children between 2003 and 2013. Children affected by histologically confirmed RMS occurring as a primary lesion in the orofacial area were included. The median age was 8 ± 4.22 years (range: 3 months - 15 years). The male to female ratio was 1.8:1. Most of the patients had advanced stage disease at presentation (81.7% group had 3-4 pretreatment staging) with parameningeal involvement in 80.6% of the cases. The 2-year event-free survival rate was 17.7 ± 7.8% for all the patients. Delay of admission to our unit and abandonment of treatment seem to be important factors for the dismal prognosis. Patient's location, socioeconomic status and health care coverage have had an impact on longer delays in seeking care and on follow-up. More studies are needed for implementation of a better management practices and a better supportive care upon specificities of our population.

  2. Advanced Propulsion System Studies for General Aviation Aircraft

    Science.gov (United States)

    Eisenberg, Joseph D. (Technical Monitor); German, Jon

    2003-01-01

    This final report addresses the following topics: Market Impact Analysis (1) assessment of general aviation, including commuter/regional, aircraft market impact due to incorporation of advanced technology propulsion system on acquisition and operating costs, job creation and/or manpower demand, and future fleet size; (2) selecting an aircraft and engine for the study by focusing on the next generation 19-passenger commuter and the Williams International FJ44 turbofan engine growth. Propulsion System Analysis Conducted mission analysis studies and engine cycle analysis to define a new commuter mission and required engine performance, define acquisition and operating costs and, select engine configuration and initiated preliminary design for hardware modifications required. Propulsion System Benefits (1) assessed and defined engine emissions improvements, (2) assessed and defined noise reduction potential and, (3) conducted a cost analysis impact study. Review of Relevant NASA Programs Conducted literature searches using NERAC and NASA RECON services for related technology in the emissions and acoustics area. Preliminary Technology Development Plans Defined plan to incorporate technology improvements for an FJ44-2 growth engine in performance, emissions, and noise suppression.

  3. Enteral Feeding During Chemoradiotherapy for Advanced Head-and-Neck Cancer: A Single-Institution Experience Using a Reactive Approach

    International Nuclear Information System (INIS)

    Clavel, Sebastien; Fortin, Bernard; Despres, Philippe; Donath, David; Soulieres, Denis; Khaouam, Nader; Charpentier, Danielle; Belair, Manon; Guertin, Louis; Nguyen-Tan, Phuc Felix

    2011-01-01

    Purpose: The optimal method for providing enteral nutrition to patients with head-and-neck cancer is unclear. The purpose of the present study was to evaluate the safety and efficacy of our reactive policy, which consists of the installation of a nasogastric (NG) feeding tube only when required by the patient's nutritional status. Methods and Materials: The records of all patients with Stage III and IV head-and-neck cancer treated with concomitant chemotherapy and radiotherapy between January 2003 and December 2006 were reviewed. The overall and disease-free survival rates were estimated using the Kaplan-Meier method and compared with the log-rank test. Results: The present study included 253 patients, and the median follow-up was 33 months. At 3 years, the estimated overall survival and disease-free survival rate was 82.8% and 77.8%, respectively, for the whole population. No survival difference was observed when the patients were compared according to the presence and absence of a NG tube or stratified by weight loss quartile. The mean weight loss during treatment for all patients was 10.4%. The proportion of patients requiring a NG tube was 49.8%, and the NG tube remained in place for a median duration of 40 days. No major complications were associated with NG tube installation. Only 3% of the patients were still dependent on enteral feeding at 6 months. Conclusion: These results suggest that the use of a reactive NG tube with an interdisciplinary team approach is a safe and effective method to manage malnutrition in patients treated with concomitant chemotherapy and radiotherapy for head-and-neck cancer.

  4. A Case Study of Organizational Collaboration in an Institution of Higher Education

    Science.gov (United States)

    Schmaltz, Sarah Katherine Abrams

    2010-01-01

    The study, A Case Study of Organizational Collaboration in an Institution of Higher Education, is a look into what is working and what is not working inside a collaborative initiative at the University of Virginia called the Partners for Leadership in Education. The Partners for Leadership in Education is one of the longest lasting collaborations…

  5. The University of California Institute of Environmental Stress Marathon Field Studies

    Science.gov (United States)

    Maron, Michael B.

    2014-01-01

    In 1973, the Institute of Environmental Stress of the University of California-Santa Barbara, under the direction of Steven M. Horvath, began a series of field and laboratory studies of marathon runners during competition. As one of Horvath's graduate students, many of these studies became part of my doctoral dissertation. The rationale for…

  6. Phenomenological Study of Business Models Used to Scale Online Enrollment at Institutions of Higher Education

    Science.gov (United States)

    Williams, Dana E.

    2012-01-01

    The purpose of this qualitative phenomenological study was to explore factors for selecting a business model for scaling online enrollment by institutions of higher education. The goal was to explore the lived experiences of academic industry experts involved in the selection process. The research question for this study was: What were the lived…

  7. International Study in the Global South: Linking Institutional, Staff, Student and Knowledge Mobilities

    Science.gov (United States)

    Gunter, Ashley; Raghuram, Parvati

    2018-01-01

    The international mobility of institutions, staff, students and knowledge resources such as books and study materials has usually been studied separately. This paper, for the first time, brings these different forms of knowledge mobilities together. Through a historical analysis of South African higher education alongside results from a…

  8. 77 FR 27776 - Safety and Occupational Health Study Section (SOHSS), National Institute for Occupational Safety...

    Science.gov (United States)

    2012-05-11

    ... Occupational Health Study Section (SOHSS), National Institute for Occupational Safety and Health (NIOSH) In... Services Office, CDC, pursuant to Public Law 92-463. Purpose: The Safety and Occupational Health Study... standard grants review and funding cycles pertaining to research issues in occupational safety and health...

  9. 76 FR 18220 - Safety and Occupational Health Study Section (SOHSS), National Institute for Occupational Safety...

    Science.gov (United States)

    2011-04-01

    ... Occupational Health Study Section (SOHSS), National Institute for Occupational Safety and Health (NIOSH) In... Services Office, CDC, pursuant to Public Law 92-463. Purpose: The Safety and Occupational Health Study... standard grants review and funding cycles pertaining to research issues in occupational safety and health...

  10. 75 FR 26266 - Safety and Occupational Health Study Section (SOHSS), National Institute for Occupational Safety...

    Science.gov (United States)

    2010-05-11

    ... Occupational Health Study Section (SOHSS), National Institute for Occupational Safety and Health (NIOSH) In...) Public Law 92-463. Purpose: The Safety and Occupational Health Study Section will review, discuss, and... cycles pertaining to research issues in occupational safety and health, and allied areas. It is the...

  11. A Feasibility Study of Neoadjuvant XELOX Without Radiotherapy for Locally Advanced Lower Rectal Cancer.

    Science.gov (United States)

    Ueki, Takashi; Manabe, Tatsuya; Inoue, Shigetaka; Ienaga, Jun; Yamanaka, Naoki; Egami, Takuya; Ishikawa, Mikimasa; Konomi, Hiroyuki; Ikubo, Akashi; Nagayoshi, Kinuko; Nakamura, Masafumi; Tanaka, Masao

    2016-02-01

    This study was planned to evaluate the efficacy and safety of preoperative capecitabine and oxaliplatin (XELOX) without radiation in patients with locally advanced lower rectal cancer. Patients with clinical stage II/III lower rectal cancer underwent three cycles of XELOX followed by radical surgery. The primary end-point was the R0 resection rate. Thirty-one patients were recruited between February 2012 and August 2014. The completion rate of neoadjuvant chemotherapy was 96.5% among the 29 patients who received it; the remaining two refused chemotherapy and underwent immediate surgery. Grade 3-4 adverse events occurred in nine patients (31%). All 29 patients who received chemotherapy underwent radical resection. The R0 resection rate was 96.5% among these 29 patients. Pathological complete responses were achieved in three patients (10.3%) and downstaging occurred in 13 (44.8%). This pilot study found that neoadjuvant XELOX for locally advanced lower rectal cancer is feasible and safe. This neoadjuvant treatment improved resection margin status. Copyright© 2016 International Institute of Anticancer Research (Dr. John G. Delinassios), All rights reserved.

  12. The study of multi-institutional collaborations in high-energy physics

    International Nuclear Information System (INIS)

    1991-01-01

    Since World War II, the organizational framework for scientific research is increasingly the multi-institutional collaboration, especially in high-energy physics. A broad preliminary survey, into the functioning of research collaborations involving three or more institutions is described. The study is designed to identify patterns of collaborations, define the scope of the documentation problems, field-test possible solutions, recommend future actions, and build an archives of oral history interviews and other resources for scholarly use. Once the study is completed, its findings will be used to promote systems to document significant collaborative research

  13. The study of multi-institutional collaborations in high-energy physics

    Energy Technology Data Exchange (ETDEWEB)

    Warnow-Blewett, Joan

    1991-01-01

    Since World War II, the organizational framework for scientific research is increasingly the multi-institutional collaboration, especially in high-energy physics. A broad preliminary survey, into the functioning of research collaborations involving three or more institutions is described. The study is designed to identify patterns of collaborations, define the scope of the documentation problems, field-test possible solutions, recommend future actions, and build an archives of oral history interviews and other resources for scholarly use. Once the study is completed, its findings will be used to promote systems to document significant collaborative research.

  14. Advanced maternal age and risk perception: A qualitative study

    Science.gov (United States)

    2012-01-01

    Background Advanced maternal age (AMA) is associated with several adverse pregnancy outcomes, hence these pregnancies are considered to be “high risk.” A review of the empirical literature suggests that it is not clear how women of AMA evaluate their pregnancy risk. This study aimed to address this gap by exploring the risk perception of pregnant women of AMA. Methods A qualitative descriptive study was undertaken to obtain a rich and detailed source of explanatory data regarding perceived pregnancy risk of 15 women of AMA. The sample was recruited from a variety of settings in Winnipeg, Canada. In-depth interviews were conducted with nulliparous women aged 35 years or older, in their third trimester, and with singleton pregnancies. Interviews were recorded and transcribed verbatim, and content analysis was used to identify themes and categories. Results Four main themes emerged: definition of pregnancy risk, factors influencing risk perception, risk alleviation strategies, and risk communication with health professionals. Conclusions Several factors may influence women's perception of pregnancy risk including medical risk, psychological elements, characteristics of the risk, stage of pregnancy, and health care provider’s opinion. Understanding these influential factors may help health professionals who care for pregnant women of AMA to gain insight into their perspectives on pregnancy risk and improve the effectiveness of risk communication strategies with this group. PMID:22988825

  15. Recent advances in study of uranium surface chemistry in China

    Energy Technology Data Exchange (ETDEWEB)

    Luo, Lizhu; Lai, Xinchun [Science and Technology on Surface Physics and Chemistry Laboratory, Sichuan (China); Wang, Xiaolin [China Academy of Engineering Physics, Sichuan (China)

    2014-04-01

    Uranium is very important in nuclear energy industry; however, uranium and its alloys corrode seriously in various atmospheres because of their chemical reactivities. In China, continuous investigations focused on surface chemistry have been carried out for a thorough understanding of uranium in order to provide technical support for its engineering applications. Oxidation kinetics of uranium and its alloys in oxidizing atmospheres are in good agreement with those in the literature. In addition to the traditional techniques, non-traditional methods have been applied for oxidation kinetics of uranium, and it has been verified that spectroscopic ellipsometry and X-ray diffraction are effective and nondestructive tools for in situ kinetic studies. The inhibition efficiency of oxidizing gas impurities on uranium hydrogenation is found to follow the order CO{sub 2} > CO > O{sub 2}, and the broadening of XPS shoulders with temperature in depth profile of hydrogenated uranium surface is discussed, which is not mentioned in the literature. Significant progress on surface chemistry of alloyed uranium (U-Nb and U-Ti) in hydrogen atmosphere is reported, and it is revealed that the hydrating nucleation and subsequent growth of alloyed uranium are closely connected with the surface states, underlying metal matrix, and it is microstructure-dependent. In this review, the recent advances in uranium surface chemistry in China, published so far mostly in Chinese language, are briefly summarized. Suggestions for further study are made. (orig.)

  16. Recent advances in study of uranium surface chemistry in China

    International Nuclear Information System (INIS)

    Luo, Lizhu; Lai, Xinchun; Wang, Xiaolin

    2014-01-01

    Uranium is very important in nuclear energy industry; however, uranium and its alloys corrode seriously in various atmospheres because of their chemical reactivities. In China, continuous investigations focused on surface chemistry have been carried out for a thorough understanding of uranium in order to provide technical support for its engineering applications. Oxidation kinetics of uranium and its alloys in oxidizing atmospheres are in good agreement with those in the literature. In addition to the traditional techniques, non-traditional methods have been applied for oxidation kinetics of uranium, and it has been verified that spectroscopic ellipsometry and X-ray diffraction are effective and nondestructive tools for in situ kinetic studies. The inhibition efficiency of oxidizing gas impurities on uranium hydrogenation is found to follow the order CO 2 > CO > O 2 , and the broadening of XPS shoulders with temperature in depth profile of hydrogenated uranium surface is discussed, which is not mentioned in the literature. Significant progress on surface chemistry of alloyed uranium (U-Nb and U-Ti) in hydrogen atmosphere is reported, and it is revealed that the hydrating nucleation and subsequent growth of alloyed uranium are closely connected with the surface states, underlying metal matrix, and it is microstructure-dependent. In this review, the recent advances in uranium surface chemistry in China, published so far mostly in Chinese language, are briefly summarized. Suggestions for further study are made. (orig.)

  17. A pilot study of bendamustine in advanced bile duct cancer.

    Science.gov (United States)

    Schoppmeyer, Konrad; Kreth, Florian; Wiedmann, Marcus; Mössner, Joachim; Preiss, Rainer; Caca, Karel

    2007-07-01

    We performed a pilot study to evaluate the safety and tolerability of bendamustine in patients with advanced hilar bile duct cancer and impaired liver function. Six patients with histologically proven, unresectable adenocarcinoma of the hilar bile duct were treated with bendamustine 140 mg/m intravenously on day 1 of the first cycle and with bendamustine 100 mg/m on days 1 and 2 of the second to fourth cycle. Treatment cycles were repeated every 21 days. Primary endpoint was the safety and tolerability of the treatment; secondary endpoints were response rate, time to progression and overall survival. Transient lymphopenia grade 3 occurred in all six patients. No other grade 3 or 4 toxicities were present. The most common nonhematologic toxicity was mouth dryness grade 2 in six patients. Three patients had stable disease. No partial or complete responses were observed. Median time to progression was 3.3 months; median overall survival was 6 months. Our study demonstrates that bendamustine can be safely administered in patients with hilar bile duct cancer and impaired liver function. A potential role of bendamustine in combination therapies for bile duct cancer will be a subject of further trials.

  18. Foresight Study on Advanced Conversion Technologies of Fossil Fuels

    International Nuclear Information System (INIS)

    Claver, A.; Cabrera, J. A.

    2000-01-01

    The Observatorio de Prospectiva Tecnologica Industrial (OPTI) is a Foundation supported by the Ministry of Industry and Energy, (MINER) and has as main objective to provide a basic information and knowledge on technology evolution. This information will be accessible to the Administration and to the Companies and can be taking into account in planning and decision making of technology policies. Ciemat is member of OPTI and is the organism in charge of the actions in the Energy sector. CIEMAT has the responsibility on the realisation of the sector studies to get in three years (1998 to 2001) a foresight vision of the critical technology topics. The OPTI integrated strategic plan undertake the analysis of other seven technology sectors, with the same criteria on methodological aspects. Delphi method was used for the realization of the studies. It consisted of a survey conducted in two rounds using a questionnaire to check the experts opinion. The time frame of the studies was defined from 1999 to 2015. The study presented in this document has been performed by CIEMAT in the second stage of the OPTI activities. The main goal behind this study is to identify the advanced clean and efficient technologies for the conversion of fossil fuels to promote in our country. The questionnaire was addressed to 250 experts and the response rate was about the 37%, ratifying the final results. The spanish position and the barriers for the development of each technology has been determined and also the recommended measures to facilitate their performance in the future. This basic information is consider of main interest, taking in account the actual energetic situation with a foreseeable demand increase and fossil fuels dependence. (Author) 17 refs

  19. A Longitudinal Study of Academic Progress Rate as a Result of Team and Institutional Variables at NCAA Division I Schools

    Science.gov (United States)

    Hale, Jimmie Edwin

    2014-01-01

    This study explained Academic Progress Rate (APR) levels and differences in APR (DAPR) with team and institutional variables. Team variables included team gender, sport profile, and squad size. Institutional variables included individual variables aggregated to the institutional level. The data analyzed in this study was derived from the National…

  20. An evaluation study of research efficiency of the Guangzhou institute of respiratory diseases based on malmquist index.

    Science.gov (United States)

    Liao, Jian-Feng; Wang, Juan; Liang, Liang; Wu, Yong-Ding; Huang, Mei-Juan; Liu, Tian-Qiang; Zhou, Lin; Wang, Xin-Wang

    2016-10-01

    This study aimed to analyze the dynamic changes of the scientific research innovation efficiency of Guangzhou Institute of Respiratory Diseases (GIRD) during the year 2009-2013 to explore the reason for these changes and give some suggestions on how to improve the overall efficiency of the Institute. The panel data used in this study were taken from 19 research teams of GIRD during 2009 to 2013. Data envelopment analysis (DEA) based on Malmquist index (MI) was used to analyze the performance of each research team in terms of productivity changes over time. Data were analyzed using DEAP 2.1 software. The annual average increase rate of total factor productivity (TFP), technological progress, technical efficiency, pure technical efficiency, and scale efficiency was 30.4%, 22.5%, 6.4%, 0.9%, and 5.4%, respectively from 2009 to 2013. The scientific research innovation efficiency of the GIRD was generally high and kept on growing. The increase of TFP was mainly caused by the progress of tech, the descending of TFP in some teams should be mainly attributable to the declining pure technical efficiency, and scale efficiency on the whole, maintaining a stable growth at a low speed. To achieve higher scientific research innovation, GIRD not only needs to further improve the management level and introduce advanced management mode, but also needs to focus on optimization of resource allocation, as well as to strengthen the talent introduction, and continue to maintain the absorption of new technologies and innovation.

  1. Radionuclide Emission Estimation for the Center for Advanced Energy Studies (CAES)

    International Nuclear Information System (INIS)

    Schrader, Bradley J.

    2010-01-01

    An Radiological Safety Analysis Computer Program (RSAC)-7 model dose assessment was performed to evaluate maximum Center for Advanced Energy Studies (CAES) boundary effective dose equivalent (EDE, in mrem/yr) for potential individual releases of radionuclides from the facility. The CAES is a public/private partnership between the State of Idaho and its academic research institutions, the federal government through the U.S. Department of Energy (DOE), and the Idaho National Laboratory (INL) managed by the Battelle Energy Alliance (BEA). CAES serves to advance energy security for our nation by expanding educational opportunities at Idaho universities in energy-related areas, creating new capabilities within its member institutions, and delivering technological innovations leading to technology-based economic development for the intermountain region. CAES has developed a strategic plan (INL/EXT-07-12950) based on the balanced scorecard approach. At the present time it is unknown exactly what processes will be used in the facility in support of this strategic plan. What is known is that the Idaho State University (ISU) Radioactive Materials License (Nuclear Regulatory Commission (NRC) license 11-27380-01) is the basis for handling radioactive material in the facility. The material in this license is shared between the ISU campus and the CAES facility. There currently are no agreements in place to limit the amount of radioactive material at the CAES facility or what is done to the material in the facility. The scope of this analysis is a summary look at the basis dose for each radionuclide included under the license at a distance of 100, 500, and 1,000 m. Inhalation, ingestion and ground surface dose was evaluated using the NRC design basis guidelines. The results can be used to determine a sum of the fractions approach to facility safety. This sum of the fractions allows a facility threshold value (TV) to be established and potential activities to be evaluated against

  2. Geographic mobility advances careers: study of the Executive Leadership in Academic Medicine (ELAM) program for women.

    Science.gov (United States)

    McLean, Marsha R; Morahan, Page S; Dannels, Sharon A; McDade, Sharon A

    2013-11-01

    To explore whether geographic mobility is associated with career advancement of women in U.S. medical schools who are entering mid- to executive-level positions. Using an existing dataset of 351 participants in academic medicine who attended the Executive Leadership in Academic Medicine (ELAM) Program for Women (1996-2005) (adjusted to 345 participants in some analyses because data on initial faculty rank were missing), the authors conducted a quantitative study in 2009 to determine whether geographic mobility was associated with administrative promotion for those who relocated geographically (from employer while attending ELAM to employer at last job of record). Twenty-four percent of women (83/345) relocated geographically (movers) after attending ELAM. Moving had a positive association with career advancement (P = .001); odds for promotion were 168% higher for movers than for stayers [odds ratio Exp(β) = 2.684]. Movers attained higher administrative positions (P = .003), and more movers (60%) were promoted at the most recent job compared with stayers (40%) (P = .0001). Few movers changed city size; 70% already resided in large or urban cities where most medical schools are located. Age was not a barrier to mobility. Career advancement was not related to research reputation (National Institutes of Health grant award ranking) of participants' schools (either at time of attending ELAM or post-ELAM). Similar to findings outside academic medicine, 24% of women classified as geographic "movers" among midcareer faculty in medical schools attained career advantages. Psychosocial and socioeconomic factors underlying women's relocation decisions require additional study.

  3. Feasibility study on the development of advanced LWR fuel technology

    Energy Technology Data Exchange (ETDEWEB)

    Jung, Youn Ho; Sohn, D. S.; Jeong, Y. H.; Song, K. W.; Song, K. N.; Chun, T. H.; Bang, J. G.; Bae, K. K.; Kim, D. H. and others

    1997-07-01

    Worldwide R and D trends related to core technology of LWR fuels and status of patents have been surveyed for the feasibility study. In addition, various fuel cycle schemes have been studied to establish the target performance parameters. For the development of cladding material, establishment of long-term research plan for alloy development and optimization of melting process and manufacturing technology were conducted. A work which could characterize the effect of sintering additives on the microstructure of UO{sub 2} pellet has been experimentally undertaken, and major sintering variables and their ranges have been found in the sintering process of UO{sub 2}-Gd{sub 2}O{sub 3} burnable absorber pellet. The analysis of state of the art technology related to flow mixing device for spacer grid and debris filtering device for bottom nozzle and the investigation of the physical phenomena related to CHF enhancement and the establishment of the data base for thermal-hydraulic performance tests has been done in this study. In addition, survey on the documents of the up-to-date PWR fuel assemblies developed by foreign vendors have been carried out to understand their R and D trends and establish the direction of R and D for these structural components. And, to set the performance target of the new fuel, to be developed, fuel burnup and economy under the extended fuel cycle length scheme were estimated. A preliminary study on the failure mechanism of CANDU fuel, key technology and advanced coating has been performed. (author). 190 refs., 31 tabs., 129 figs.

  4. An Exploratory Study of Accounting on Ijarah as Practiced by Malaysian Financial Institutions

    OpenAIRE

    Shariff, Ros Aniza Mohd; Abdul Rahman, Abdul Rahim

    2005-01-01

    Prior studies on Ijarah were mainly focusing on the economics, legal and financial aspects, there was, however, so far no in- depth study on accounting for Ijarah. The main objective of this study is to explore the nature of accounting practices as practiced by Malaysian financial institutions. First, the study makes comparison between the Intemational Accounting Standard on leasing (IAS 17); the accounting standard for Ijarah (FAS 8) as developed by the Accounting and Auditing Organization for...

  5. A Study on Course Management System Implementation in Indonesian Higher Education Institutions

    Science.gov (United States)

    Saputra, Y. A.; Singgih, M. L.; Latiffianti, E.; Suryani, E.; Mudjahidin

    2018-04-01

    Information technology development nowadays has brought new colors in the higher education learning process. In Indonesia, the current trend showed a higher use of CMS to support the existing conventional learning method in the classrooms. This paper attempts to understand the characteristics of CMS implementation based on a survey at several higher education institutions in Indonesia. There were 9 selected higher education institutions observed in this study. The objectives were to find out the CMS implementation in terms of: 1) the management of CMS implementation, 2) the evaluation, 3) originality of materials, platform, and feature; and 4) participation level. The result showed that the use of CMS in these institutions, in general, was to support the classroom conventional learning method by providing a repository of lecture notes and communication forum/media outside the classroom. The management task mostly was taken care by a specific unit. A Moodle (freeware) was found as a typical platform in use, and none of the institutions chose to use paid platform i.e. Blackboard. The accessibility of CMS used was kept closed for limited group of people due to high cost of material originality assurance. Observation also found that there was not much attempts in evaluating the success of CMS implementation in each institution, whereas the success measurement was limited to the users’ satisfaction level. The majority of institutions claimed a good internal participation level (with lecturers and students as the main users), but in general we found that lecturer participation in most institutions were low or even very low.

  6. Determinants of institutional delivery among childbearing age women in Western Ethiopia, 2013: unmatched case control study.

    Directory of Open Access Journals (Sweden)

    Tesfaye Regassa Feyissa

    Full Text Available BACKGROUND: Place of delivery is a crucial factor which affects the health and wellbeing of the mother and newborn. Institutional delivery helps the women to access skilled assistance, drugs, equipment, and referral transport. Even though 34% of pregnant women received at least one antenatal care from a skilled provider in Ethiopia by 2013, institutional delivery was 10%. The main objective of the study was to assess determinants of institutional delivery in Western Ethiopia. METHODS: Retrospective unmatched case control study design was used to assess determinants of institutional delivery in Western Ethiopia from September to October 2013. A total of 320 respondents from six districts of East Wollega zone, West Ethiopia were included. Data were collected using pretested and structured questionnaires. Data were entered and cleaned by Epi-info then exported and analyzed using SPSS software. Statistical significance was determined through a 95% confidence level. RESULTS: Education [Adjusted Odds Ratio (AOR (95% Confidence Interval (CI = 2.754(1.510-8.911], family size [AOR (95% CI = .454(.209-.984], residence [AOR (95% CI = 3.822 (1.766-8.272] were important predictors of place of delivery. Four or more antenatal care [(ANC (AOR (95% CI = 2.914(1.105-7.682], birth order [(AOR (95% CI = .136(.054-.344, age at last delivery [(AOR (95% CI = 9.995(2.101-47.556], birth preparedness [AOR (95% CI = 6.957(2.422-19.987], duration of labour [AOR (95% CI = 3.541(1.732-7.239] were significantly associated with institutional delivery. Moreover service related factors such as distance from health institutions [AOR (95% CI = .665(.173-.954], respondents' awareness of skill of health care professionals [AOR (95% CI = 2.454 (1.663-6.255], mode of transportations [AOR (95% CI = .258(.122-.549] were significantly associated with institutional delivery. CONCLUSIONS AND RECOMMENDATIONS: Policy makers, health service

  7. Determinants of institutional delivery among childbearing age women in Western Ethiopia, 2013: unmatched case control study.

    Science.gov (United States)

    Feyissa, Tesfaye Regassa; Genemo, Gebi Agero

    2014-01-01

    Place of delivery is a crucial factor which affects the health and wellbeing of the mother and newborn. Institutional delivery helps the women to access skilled assistance, drugs, equipment, and referral transport. Even though 34% of pregnant women received at least one antenatal care from a skilled provider in Ethiopia by 2013, institutional delivery was 10%. The main objective of the study was to assess determinants of institutional delivery in Western Ethiopia. Retrospective unmatched case control study design was used to assess determinants of institutional delivery in Western Ethiopia from September to October 2013. A total of 320 respondents from six districts of East Wollega zone, West Ethiopia were included. Data were collected using pretested and structured questionnaires. Data were entered and cleaned by Epi-info then exported and analyzed using SPSS software. Statistical significance was determined through a 95% confidence level. Education [Adjusted Odds Ratio (AOR) (95% Confidence Interval (CI)) = 2.754(1.510-8.911)], family size [AOR (95% CI) = .454(.209-.984)], residence [AOR (95% CI) = 3.822 (1.766-8.272)] were important predictors of place of delivery. Four or more antenatal care [(ANC) (AOR (95% CI) = 2.914(1.105-7.682)], birth order [(AOR (95% CI) = .136(.054-.344), age at last delivery [(AOR (95% CI) = 9.995(2.101-47.556)], birth preparedness [AOR (95% CI) = 6.957(2.422-19.987)], duration of labour [AOR (95% CI) = 3.541(1.732-7.239)] were significantly associated with institutional delivery. Moreover service related factors such as distance from health institutions [AOR (95% CI) = .665(.173-.954)], respondents' awareness of skill of health care professionals [AOR (95% CI) = 2.454 (1.663-6.255)], mode of transportations [AOR (95% CI) = .258(.122-.549)] were significantly associated with institutional delivery. Policy makers, health service organizations, community leaders and other concerned bodies have

  8. Phase 2 Study of Bevacizumab Plus Erlotinib in Patients With Advanced Hepatocellular Cancer

    Science.gov (United States)

    Philip, Philip A.; Mahoney, Michelle R.; Holen, Kyle D.; Northfelt, Donald W.; Pitot, Henry C.; Picus, Joel; Flynn, Patrick J.; Erlichman, Charles

    2013-01-01

    BACKGROUND Epidermal growth factor receptor (EGFR) and vascular endothelial growth factor (VEGF) are rational targets for therapy in hepatocellular cancer (HCC). METHODS Patients with histologically proven HCC and not amenable to curative or liver directed therapy were included in this 2-stage phase 2 trial. Eligibility included an Eastern Cooperative Oncology Group (ECOG) performance status (PS) of 0 or 1 and Child’s Pugh score of A or B, and 1 prior systemic therapy. Patients received erlotinib 150 mg daily and bevacizumab 10 mg/kg on days 1 and 15 every 28 days. Objective tumor response was the primary end point. RESULTS Twenty-seven patients with advanced HCC (median age, 60 years) were enrolled in this multi-institutional study. The proportion of patients with Child’s A classification was 74%. One patient had a confirmed partial response and 11 (48%) achieved stable disease. Median time to disease progression was 3.0 months (95% confidence interval [CI], 1.8-7.1). Median survival time was 9.5 months (95% CI, 7.1-17.1). Grade 3 toxicities included rash, hypertension, fatigue, and diarrhea. CONCLUSIONS In this trial, erlotinib combined with bevacizumab had minimal activity in patients with advanced HCC based on objective response and progression-free survival. The role of targeting EGFR and VEGF in HCC needs further evaluation in molecularly selected patients. PMID:21953248

  9. Pulpal changes associated with advanced periodontal disease: A histopathological study.

    Science.gov (United States)

    Gautam, Siddharth; Galgali, Sushama R; Sheethal, H S; Priya, N S

    2017-01-01

    Over the past century, the dental literature has consistently reflected a controversy related to the effect of periodontal disease on the dental pulp. Nonetheless, practitioners are of the opinion that teeth having deep periodontal pockets show variable pulpal response, which may necessitate root canal treatment. Thus, this study aimed to evaluate the changes in pulp due to advanced periodontal disease. Forty caries-free teeth affected with severe periodontitis were collected from patients aged between 18 and 55 years. The collected teeth were stored in formalin for 24 h and were then decalcified and examined histologically after staining with hematoxylin and eosin to note the changes that occurred in pulp. Pulpal calcification (52.62%) and partial necrosis of pulp (52.62%) were found to be the most common findings. Inflammation, which was found in 47.38% of the cases, ranged from mild to severe in most sections and was always chronic. Pulp with complete necrosis was seen in 26.32% of cases. Fibrosis and pulpal edema were seen in 36.84% of cases. In the presence of moderate to severe chronic periodontitis, degenerative changes such as inflammation, fibrosis, edema, calcification and necrosis were observed to variable degree.

  10. Study of an advanced General Aviation Turbine Engine (GATE)

    Science.gov (United States)

    Gill, J. C.; Short, F. R.; Staton, D. V.; Zolezzi, B. A.; Curry, C. E.; Orelup, M. J.; Vaught, J. M.; Humphrey, J. M.

    1979-01-01

    The best technology program for a small, economically viable gas turbine engine applicable to the general aviation helicopter and aircraft market for 1985-1990 was studied. Turboshaft and turboprop engines in the 112 to 746 kW (150 to 1000 hp) range and turbofan engines up to 6672 N (1500 lbf) thrust were considered. A good market for new turbine engines was predicted for 1988 providing aircraft are designed to capitalize on the advantages of the turbine engine. Parametric engine families were defined in terms of design and off-design performance, mass, and cost. These were evaluated in aircraft design missions selected to represent important market segments for fixed and rotary-wing applications. Payoff parameters influenced by engine cycle and configuration changes were aircraft gross mass, acquisition cost, total cost of ownership, and cash flow. Significant advantage over a current technology, small gas turbine engines was found especially in cost of ownership and fuel economy for airframes incorporating an air-cooled high-pressure ratio engine. A power class of 373 kW (500 hp) was recommended as the next frontier for technology advance where large improvements in fuel economy and engine mass appear possible through component research and development.

  11. Nonhuman Primate Studies to Advance Vision Science and Prevent Blindness.

    Science.gov (United States)

    Mustari, Michael J

    2017-12-01

    Most primate behavior is dependent on high acuity vision. Optimal visual performance in primates depends heavily upon frontally placed eyes, retinal specializations, and binocular vision. To see an object clearly its image must be placed on or near the fovea of each eye. The oculomotor system is responsible for maintaining precise eye alignment during fixation and generating eye movements to track moving targets. The visual system of nonhuman primates has a similar anatomical organization and functional capability to that of humans. This allows results obtained in nonhuman primates to be applied to humans. The visual and oculomotor systems of primates are immature at birth and sensitive to the quality of binocular visual and eye movement experience during the first months of life. Disruption of postnatal experience can lead to problems in eye alignment (strabismus), amblyopia, unsteady gaze (nystagmus), and defective eye movements. Recent studies in nonhuman primates have begun to discover the neural mechanisms associated with these conditions. In addition, genetic defects that target the retina can lead to blindness. A variety of approaches including gene therapy, stem cell treatment, neuroprosthetics, and optogenetics are currently being used to restore function associated with retinal diseases. Nonhuman primates often provide the best animal model for advancing fundamental knowledge and developing new treatments and cures for blinding diseases. © The Author(s) 2017. Published by Oxford University Press on behalf of the National Academy of Sciences. All rights reserved. For permissions, please email: journals.permissions@oup.com.

  12. Legal and Institutional Issues of Transportable Nuclear Power Plants: A Preliminary Study

    International Nuclear Information System (INIS)

    2013-01-01

    jointly the international and national actions required for ensuring the sustainability of nuclear energy through innovations in technology and/or institutional arrangements. A transportable nuclear power plant (TNPP) is a factory manufactured, transportable and relocatable nuclear power plant which, when fuelled, is capable of producing final energy products such as electricity and heat. Introducing a TNPP may require fewer financial and human resources from the host State. However, the deployment of such reactors will face new legal issues in the international context which need to be resolved to enable the deployment of such reactors in countries other than the country of origin. The objective of this report is to study the legal and institutional issues for the deployment of TNPPs, to reveal challenges that might be faced in their deployment, and to outline pathways for resolution of the identified issues and challenges in the short and long terms. It is addressed to senior legal, regulatory and technical officers in Member States planning to embark on a nuclear power programme or to expand an existing one by considering the introduction of a TNPP

  13. Implementation of Advanced Warehouses in a Hospital Environment - Case study

    Science.gov (United States)

    Costa, J.; Sameiro Carvalho, M.; Nobre, A.

    2015-05-01

    In Portugal, there is an increase of costs in the healthcare sector due to several factors such as the aging of the population, the increased demand for health care services and the increasing investment in new technologies. Thus, there is a need to reduce costs, by presenting the effective and efficient management of logistics supply systems with enormous potential to achieve savings in health care organizations without compromising the quality of the provided service, which is a critical factor, in this type of sector. In this research project the implementation of Advanced Warehouses has been studied, in the Hospital de Braga patient care units, based in a mix of replenishment systems approaches: the par level system, the two bin system and the consignment model. The logistics supply process is supported by information technology (IT), allowing a proactive replacement of products, based on the hospital services consumption records. The case study was developed in two patient care units, in order to study the impact of the operation of the three replenishment systems. Results showed that an important inventory holding costs reduction can be achieved in the patient care unit warehouses while increasing the service level and increasing control of incoming and stored materials with less human resources. The main conclusion of this work illustrates the possibility of operating multiple replenishment models, according to the types of materials that healthcare organizations deal with, so that they are able to provide quality health care services at a reduced cost and economically sustainable. The adoption of adequate IT has been shown critical for the success of the project.

  14. Management of information security risks in a federal public institution: a case study

    Directory of Open Access Journals (Sweden)

    Jackson Gomes Soares Souza

    2016-11-01

    Full Text Available Public institutions bound to the Brazilian federal public sector must apply security measures, policies, procedures and guidelines as information assets protection measures. This case study sought to determine whether the management of information security risks is applied in a federal public institution according to Information Technology (I.T. managers perceptions and the results expose the importance of the roles played by people, responsibilities, policies, standards, procedures and their implementation aiming greater control of information security risks and opportunities related to information technology security.

  15. Institutional analysis of incentive schemes for ecosystem service provision - a comparative study across four European countries

    DEFF Research Database (Denmark)

    Prokofieva, Irina; Górriz, Elena; Boon, Tove Enggrob

    2014-01-01

    Incentive schemes and payments for ecosystem services attract increasing attention as a means for aligning the interests of landowners and society by remunerating forest owners for the goods and services their forests produce. As incentive schemes expand around the world, questions related...... and Italy. The analysed schemes are predominantly aimed at enhancing biodiversity and improving recreation. One of the schemes is also related to preserving a variety of forest ecosystem services from forest fires. The incentive schemes are studied following a framework for the institutional analysis of PES...... developed by Prokofieva and Gorriz (Prokofieva, I. and Gorriz, E. 2013: Institutional analysis of incentives for the provision of forest goods and services: an assessment of incentive schemes in Catalonia (North-East Spain), Forest Policy and Economics, 37, 104-114.). We focus on actor and institutional...

  16. The Metropolitan Studies Institute at USC Upstate: Translational Research that Drives Community Decision-Making

    Science.gov (United States)

    Brady, Kathleen

    2012-01-01

    The Metropolitan Studies Institute (MSI) at the University of South Carolina Upstate (USC Upstate) demonstrates a robust and unique record of community impact through community indicators research and other translational research. The MSI's work drives programmatic priorities and funding decisions, generates revenue, and increases the community's…

  17. Variations in Student Perceptions of Service Quality of Higher Education Institutions in Brazil: A Longitudinal Study

    Science.gov (United States)

    Campos, Domingos Fernandes; dos Santos, Guido Salvi; Castro, Felipe Nalon

    2017-01-01

    Purpose: The purpose of this paper is to examine, through a longitudinal study, undergraduate student perceptions of service expectations, priorities and quality of the higher education institution that they attend, using an importance-performance rating matrix. Design/methodology/approach: This research was carried out with students exposed to a…

  18. The Emerging Internet. Annual Review of the Institute for Information Studies.

    Science.gov (United States)

    Institute for Information Studies, Falls Church, VA.

    This document contains papers commissioned by the Institute for Information Studies to provide a variety of perspectives on a particular topic relating to the impact of communications and information technology. Among the subjects covered are the impact of the Internet on community, education, electronic commerce, international development, and…

  19. Institute for Fusion Studies, Final Technical Report, December 1, 1995 - February 29, 2004

    International Nuclear Information System (INIS)

    Dr. James Van Dam

    2005-01-01

    During the 2001-2003 grant period, Institute for Fusion Studies (IFS) scientist made notable progress in a number of research areas. This report summarizes the work that has been accomplished in the following areas: (1) Magnetohydrodynamics; (2) Burning plasma and energetic particle physics; (3) Turbulent transport; (4) Computational physics; (5) Fundamental Theory; (6) Innovative confinement concepts; and (7) Plasma applications

  20. The Impact of Institutional Differences on Derivatives Usage : A Comparative Study of US and Dutch Firms

    NARCIS (Netherlands)

    Bodnar, G.M.; de Jong, A.; Macrae, V.

    2001-01-01

    This paper tests the influence of institutional differences on risk management practices.Several survey studies have investigated derivatives usage for risk management purposes in the US (see, among others, Bodnar, Hayt, Marston and Smithson, 1995 and Bodnar, Hayt and Marston, 1996, 1998).In this

  1. Exploring the Relationship between Institutional and Professional Autonomy: A Comparative Study between Portugal and Finland

    Science.gov (United States)

    Carvalho, Teresa; Diogo, Sara

    2018-01-01

    By comparing two distinct settings--Portugal and Finland--and based on previous studies revealing similar trends in both countries, this article analyses the relationship between institutional and academic autonomy in the higher education sector. Based on crosschecking of the literature review and 47 interviews with key actors in both the…

  2. Building the Innovative and Entrepreneurial University: An Institutional Case Study of Administrative Academic Capitalism

    Science.gov (United States)

    McClure, Kevin R.

    2016-01-01

    Although researchers have explored dimensions of academic capitalism among students and faculty members, knowledge of the roles of administrators at all levels is underdeveloped in the literature. This institutional case study of a public research-extensive university examines the roles of executive and managerial administrators in bringing a…

  3. Institute for Fusion Studies, Final Technical Report, December 1, 1995 - February 29, 2004

    Energy Technology Data Exchange (ETDEWEB)

    Dr. James Van Dam

    2005-02-14

    During the 2001-2003 grant period, Institute for Fusion Studies (IFS) scientist made notable progress in a number of research areas. This report summarizes the work that has been accomplished in the following areas: (1) Magnetohydrodynamics; (2) Burning plasma and energetic particle physics; (3) Turbulent transport; (4) Computational physics; (5) Fundamental Theory; (6) Innovative confinement concepts; and (7) Plasma applications.

  4. Fulfilling an Institutional and Public Good Mission: A Case Study of Access

    Science.gov (United States)

    Batman, Renee F.

    2013-01-01

    Access to higher education has been and remains a critical issue, yet research typically focuses on students and programs which may overlook the role of the faculty. Through an in-depth case study, the perspectives of tenured and tenure-track faculty at a predominately White, Midwestern land-grant, research institution are described as they relate…

  5. Exploring Curricular Transformation to Promote Innovation and Entrepreneurship: An Institutional Case Study

    Science.gov (United States)

    McClure, Kevin R.

    2015-01-01

    Colleges and universities in the United States have developed and implemented a wide array of opportunities for undergraduate students to learn about innovation and entrepreneurship. Drawing upon an institutional case study, this article examines why one public research university initiated and supported curricular and co-curricular offerings in…

  6. A Study of Pacific Islander Scholarship Football Players and Their Institutional Experience in Higher Education

    Science.gov (United States)

    Morita, Monica K.

    2013-01-01

    This study applies the theories of social and cultural capital and introduces athletic capital in order to gain an understanding of Polynesian scholarship football players and their experiences at an institution of higher education. Additionally, theories of student identity development and student-athlete development are also utilized to gain a…

  7. Research training for teaching staff as a catalyst for professional and institutional development : a case study

    NARCIS (Netherlands)

    Crispin, Darla; Stolte, Tine; Bisschop Boele, Evert

    2015-01-01

    When an institution wishes to develop a Masters programme that combines relevance to the profession with preparation for possible 3rd cycle study, there are many things to consider: curriculum design and content, facilities, stakeholder opinion, assessment, likely student intake, etc. But at least

  8. "Burnout in Medical Oncology Fellows: a Prospective Multicenter Cohort Study in Brazilian Institutions".

    Science.gov (United States)

    Cubero, Daniel I G; Fumis, Renata Rego Lins; de Sá, Thiago Hérick; Dettino, Aldo; Costa, Felipe Osório; Van Eyll, Brigitte M R H Adam; Beato, Carlos; Peria, Fernanda Maris; Mota, Augusto; Altino, José; Azevedo, Sérgio Jobim; da Rocha Filho, Duílio Reis; Moura, Melba; Lessa, Álvaro Edson Ramos; Del Giglio, Auro

    2016-09-01

    Burnout syndrome is a common occurrence among oncologists. Doctors enrolled in residency programs in clinical oncology are exposed to similar risk factors; however, few data are available in this population. This study assessed the occurrence of burnout and associated factors among first-year residents at Brazilian institutions. The present prospective, multicenter, cohort study was conducted with doctors enrolled in residency programs in clinical oncology at Brazilian institutions affiliated with the public health system. The participants answered a sociodemographic questionnaire, the Maslach Burnout Inventory (MBI), Lipp's Stress Inventory, and the Beck Depression Inventory (BDI), upon admission to the program and 6 and 12 months later. Of 37 eligible residency programs in 2009, 11 (30.6 %) agreed to participate in the study. Fifty-four residents, representing 100 % of new admissions to the participating institutions, were included. Most of the participants met the criteria for severe burnout upon admission to the residency programs (emotional exhaustion in 49.0 % and depersonalization in 64.7 %). The scores on MBI domains emotional exhaustion and depersonalization increased significantly (p burnout increased to 88 % at the end of that first year. The present study found a high prevalence of burnout among doctors enrolled in residency programs in clinical oncology at Brazilian institutions. A large fraction of the participants met the criteria for burnout syndrome upon admission to the program, which suggests that the problem began during the course of the previous residency program in internal medicine.

  9. Education for Public Policy and Management: Views from the Institute of Social Studies, The Hague

    NARCIS (Netherlands)

    D.R. Gasper (Des); J.W. Björkman (James Warner); V. Moharir (Vasant); M.E. Wuyts (Marc)

    2000-01-01

    markdownabstractIntroduction When the Institute of Social Studies, ISS, was founded in 1952 in The Hague as a postgraduate centre for teaching and research on social and economic development, it established the first Masters programme in public administration and the first professorial chair in

  10. Advertising Online by Educational Institutions and Students' Reaction: A Study of Malaysian Universities

    Science.gov (United States)

    Jan, Muhammad Tahir; Ammari, Djihane

    2016-01-01

    This paper mainly aims to identify the impact of online advertising on students' decision-making and their choice of higher education institutions. Data for this study were collected from 350 students from various Malaysian universities using self-administered questionnaires. The acquired data went through an exhaustive process to ensure that it…

  11. 78 FR 64504 - Safety and Occupational Health Study Section (SOHSS), National Institute for Occupational Safety...

    Science.gov (United States)

    2013-10-29

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention Safety and Occupational Health Study Section (SOHSS), National Institute for Occupational Safety and Health (NIOSH or..., Number 177, Pages 56235-56236. Contact Person for More Information: Price Connor, Ph.D., NIOSH Health...

  12. Environmental Literacy Components and Their Promotion by Institutions of Higher Education: An Israeli Case Study

    Science.gov (United States)

    Arnon, Sara; Orion, Nir; Carmi, Nurit

    2015-01-01

    The recognition of the key role and moral responsibility of higher education institutions (HEIs) in cultivating the environmental literacy (EL) of their students is growing globally. The current research examined the contribution of HEIs to their students' EL by focusing on an Israeli college as a case-study. A survey was conducted among a…

  13. Homeless Students' Lived Experiences in Postsecondary Institutions and Academie: A Hermeneutic-Phenomenological Study

    Science.gov (United States)

    Bongoy, Batombo M.

    2016-01-01

    This was a hermeneutic-phenomenological study on homeless students' life-world in urban, postsecondary public educational institutions. The sample population comprised 10 male and female Hispanic, Black, and Caucasian homeless student participants enrolled in professional and academic programs in postsecondary public vocational institutions…

  14. Horizontal Stratification in Access to Danish University Programs by Institution and Field of Study

    DEFF Research Database (Denmark)

    Munk, Martin D.; Thomsen, Jens Peter

    2012-01-01

    In this paper we use register data to investigate social stratification within fields of study and university institutions in Denmark. We argue firstly, that it is important to utilize a relatively detailed classification of parents’ occupation, in order to single out how students are endowed wit...

  15. Leadership Development Institute: A California Community College Multi-College District Case Study

    Science.gov (United States)

    Leon, Bianca R.

    2016-01-01

    The purpose of this study is to examine a community college district Grow Your Own (GYO) leadership program in the Western United States, the Multi College Leadership Development Institute (MCLDI). The MCLDI was developed in-house for a multi-campus community college district and offered to interested employees at all position levels with the…

  16. A Case Study of Undergraduate Women in a Leadership Development Program at a Coeducational Institution

    Science.gov (United States)

    Haight, Lori P.

    2010-01-01

    The purpose of this interpretive case study was to explore the collegiate experiences of undergraduate women participating in a cohort women's-only leadership development program at a coeducational institution. Using a framework based on Kurt Lewin's psycho-social model of behavior being the function of a person interacting with the environment…

  17. Assessment Leaders' Perspectives of Institutional Cultures of Assessment: A Delphi Study

    Science.gov (United States)

    Fuller, Matthew; Henderson, Susan; Bustamante, Rebecca

    2015-01-01

    Institutional cultures of assessment are praised as beneficial to student learning. Yet, extant studies have not explored the theoretical foundations and pragmatic approaches to shaping cultures of assessment. The researchers used the Delphi method to explore 10 higher education assessment leaders' attitudes and theoretical perspectives regarding…

  18. Occupational Stress in UK Higher Education Institutions: A Comparative Study of All Staff Categories

    Science.gov (United States)

    Tytherleigh, M. Y.; Webb, C.; Cooper, C. L.; Ricketts, C.

    2005-01-01

    The higher education sector in the UK continues to experience significant change. This includes restructuring, use of short-term contracts, external scrutiny and accountability, and major reductions in funding. In line with this, reports of stress at work in higher education institutions have also increased. The study reported here was carried out…

  19. Colonial Institutions

    DEFF Research Database (Denmark)

    McAtackney, Laura; Palmer, Russell

    2016-01-01

    and the USA which reveal that the study of colonial institutions should not be limited to the functional life of these institutions—or solely those that take the form of monumental architecture—but should include the long shadow of “imperial debris” (Stoler 2008) and immaterial institutions....

  20. Study on advancement of in vivo counting using mathematical simulation

    Energy Technology Data Exchange (ETDEWEB)

    Kinase, Sakae [Japan Atomic Energy Research Inst., Tokai, Ibaraki (Japan). Tokai Research Establishment

    2003-05-01

    To obtain an assessment of the committed effective dose, individual monitoring for the estimation of intakes of radionuclides is required. For individual monitoring of exposure to intakes of radionuclides, direct measurement of radionuclides in the body - in vivo counting- is very useful. To advance in a precision in vivo counting which fulfills the requirements of ICRP 1990 recommendations, some problems, such as the investigation of uncertainties in estimates of body burdens by in vivo counting, and the selection of the way to improve the precision, have been studied. In the present study, a calibration technique for in vivo counting application using Monte Carlo simulation was developed. The advantage of the technique is that counting efficiency can be obtained for various shapes and sizes that are very difficult to change for phantoms. To validate the calibration technique, the response functions and counting efficiencies of a whole-body counter installed in JAERI were evaluated using the simulation and measurements. Consequently, the calculations are in good agreement with the measurements. The method for the determination of counting efficiency curves as a function of energy was developed using the present technique and a physiques correction equation was derived from the relationship between parameters of correction factor and counting efficiencies of the JAERI whole-body counter. The uncertainties in body burdens of {sup 137}Cs estimated with the JAERI whole-body counter were also investigated using the Monte Carlo simulation and measurements. It was found that the uncertainties of body burdens estimated with the whole-body counter are strongly dependent on various sources of uncertainty such as radioactivity distribution within the body and counting statistics. Furthermore, the evaluation method of the peak efficiencies of a Ge semi-conductor detector was developed by Monte Carlo simulation for optimum arrangement of Ge semi-conductor detectors for