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Sample records for advanced quantra fticr

  1. SIEMENS ADVANCED QUANTRA FTICR MASS SPECTROMETER FOR ULTRA HIGH RESOLUTION AT LOW MASS

    Energy Technology Data Exchange (ETDEWEB)

    Spencer, W; Laura Tovo, L

    2008-07-08

    The Siemens Advanced Quantra Fourier Transform Ion Cyclotron Resonance (FTICR) mass spectrometer was evaluated as an alternative instrument to large double focusing mass spectrometers for gas analysis. High resolution mass spectrometers capable of resolving the common mass isomers of the hydrogen isotopes are used to provide data for accurate loading of reservoirs and to monitor separation of tritium, deuterium, and helium. Conventional double focusing magnetic sector instruments have a resolution that is limited to about 5000. The Siemens FTICR instrument achieves resolution beyond 400,000 and could possibly resolve the tritium ion from the helium-3 ion, which differ by the weight of an electron, 0.00549 amu. Working with Y-12 and LANL, SRNL requested Siemens to modify their commercial Quantra system for low mass analysis. To achieve the required performance, Siemens had to increase the available waveform operating frequency from 5 MHz to 40 MHz and completely redesign the control electronics and software. However, they were able to use the previous ion trap, magnet, passive pump, and piezo-electric pulsed inlet valve design. NNSA invested $1M in this project and acquired four systems, two for Y-12 and one each for SRNL and LANL. Siemens claimed a $10M investment in the Quantra systems. The new Siemens Advanced Quantra demonstrated phenomenal resolution in the low mass range. Resolution greater than 400,000 was achieved for mass 2. The new spectrometer had a useful working mass range to 500 Daltons. However, experiments found that a continuous single scan from low mass to high was not possible. Two useful working ranges were established covering masses 1 to 6 and masses 12 to 500 for our studies. A compromise performance condition enabled masses 1 to 45 to be surveyed. The instrument was found to have a dynamic range of about three orders of magnitude and quantitative analysis is expected to be limited to around 5 percent without using complex fitting algorithms

  2. Tracking the Magnetron Motion in FT-ICR Mass Spectrometry

    Science.gov (United States)

    Jertz, Roland; Friedrich, Jochen; Kriete, Claudia; Nikolaev, Evgeny N.; Baykut, Gökhan

    2015-08-01

    In Fourier transform ion cyclotron resonance spectrometry (FT-ICR MS) the ion magnetron motion is not usually directly measured, yet its contribution to the performance of the FT-ICR cell is important. Its presence is manifested primarily by the appearance of even-numbered harmonics in the spectra. In this work, the relationship between the ion magnetron motion in the ICR cell and the intensities of the second harmonic signal and its sideband peak in the FT-ICR spectrum is studied. Ion motion simulations show that during a cyclotron motion excitation of ions which are offset to the cell axis, a position-dependent radial drift of the cyclotron center takes place. This radial drift can be directed outwards if the ion is initially offset towards one of the detection electrodes, or it can be directed inwards if the ion is initially offset towards one of the excitation electrodes. Consequently, a magnetron orbit diameter can increase or decrease during a resonant cyclotron excitation. A method has been developed to study this behavior of the magnetron motion by acquiring a series of FT-ICR spectra using varied post-capture delay (PCD) time intervals. PCD is the delay time after the capture of the ions in the cell before the cyclotron excitation of the ion is started. Plotting the relative intensity of the second harmonic sideband peak versus the PCD in each mass spectrum leads to an oscillating "PCD curve". The position and height of minima and maxima of this curve can be used to interpret the size and the position of the magnetron orbit. Ion motion simulations show that an off-axis magnetron orbit generates even-numbered harmonic peaks with sidebands at a distance of one magnetron frequency and multiples of it. This magnetron offset is due to a radial offset of the electric field axis versus the geometric cell axis. In this work, we also show how this offset of the radial electric field center can be corrected by applying appropriate DC correction voltages to the

  3. Vacuum Ultraviolet Photodissociation and Fourier Transform–Ion Cyclotron Resonance (FT-ICR) Mass Spectrometry: Revisited

    Energy Technology Data Exchange (ETDEWEB)

    Shaw, Jared B.; Robinson, Errol W.; Pasa-Tolic, Ljiljana

    2016-02-16

    We revisited the implementation of UVPD within the ICR cell of a FT-ICR mass spectrometer. UVPD performance characteristics were examined in the context of recent developments in the understanding of UVPD and in-cell tandem mass spectrometry. Efficient UVPD and photo-ECD of a model peptide and small protein within the ICR cell of a FT-ICR mass spectrometer are accomplished through appropriate modulation of laser pulse timing relative to ion magnetron motion and the potential applied to an ion optical element that photons impinge on. It is shown that UVPD yields efficient and extensive fragmentation resulting in excellent sequence coverage for model peptide and protein cations.

  4. Extracting biomolecule collision cross sections from the high-resolution FT-ICR mass spectral linewidths.

    Science.gov (United States)

    Jiang, Ting; Chen, Yu; Mao, Lu; Marshall, Alan G; Xu, Wei

    2016-01-14

    It is known that the ion collision cross section (CCS) may be calculated from the linewidth of a Fourier transform ion cyclotron resonance (FT-ICR) mass spectral peak at elevated pressure (e.g., ∼10(-6) Torr). However, the high mass resolution of FT-ICR is sacrificed in those experiments due to high buffer gas pressure. In this study, we describe a linewidth correction method to eliminate the windowing-induced peak broadening effect. Together with the energetic ion-neutral collision model previously developed by our group, this method enables the extraction of CCSs of biomolecules from high-resolution FT-ICR mass spectral linewidths, obtained at a typical operating buffer gas pressure of modern FT-ICR instruments (∼10(-10) Torr). CCS values of peptides including MRFA, angiotensin I, and bradykinin measured by the proposed method agree well with ion mobility measurements, and the unfolding of protein ions (ubiquitin) at higher charge states is also observed. PMID:26314765

  5. ICR studies of some anionic gas phase reactions and FTICR software design

    International Nuclear Information System (INIS)

    This thesis consists of two parts. Part one (Chs. 1-5) reports experimental results from mostly drift-cell ICR studies of negative ion-molecule reactions; part two (Chs. 6-11) concerns the design of software for an FTICR instrument. The author discusses successively: 1. ion cyclotron resonance spectrometry; 2. the gas phase allyl anion; 3. the (M-H) and (M-H2) anions from acetone; 4. negative ion-molecule reactions of aliphatic nitrites studied by cyclotron resonance; 5. homoconjugation versus charge-dipole interaction effects in the stabilization of carbanions in the gas phase; 6. the Fourier Transform ICR method; 7. the FTICR-software; 8. an efficient adaptive matcher filter for fast transient signals; 9. reduction of spectral peak height errors by time-domain weighing; 10. Chirp excitation; 11. Compact data storage. The book concludes with a Dutch and English summary (G.J.P.)

  6. Application of Printed Circuit Board Technology to FT-ICR MS Analyzer Cell Construction and Prototyping

    Science.gov (United States)

    Leach, Franklin E.; Norheim, Randolph; Anderson, Gordon; Pasa-Tolic, Ljiljana

    2014-12-01

    Although Fourier transform ion cyclotron resonance mass spectrometry (FT-ICR MS) remains the mass spectrometry platform that provides the highest levels of performance for mass accuracy and resolving power, there is room for improvement in analyzer cell design as the ideal quadrupolar trapping potential has yet to be generated for a broadband MS experiment. To this end, analyzer cell designs have improved since the field's inception, yet few research groups participate in this area because of the high cost of instrumentation efforts. As a step towards reducing this barrier to participation and allowing for more designs to be physically tested, we introduce a method of FT-ICR analyzer cell prototyping utilizing printed circuit boards at modest vacuum conditions. This method allows for inexpensive devices to be readily fabricated and tested over short intervals and should open the field to laboratories lacking or unable to access high performance machine shop facilities because of the required financial investment.

  7. The Chemical Exhaust Hazards of Dichlorosilane Deposits Determined with FT-ICR Mass Spectrometry

    Energy Technology Data Exchange (ETDEWEB)

    JAREK, RUSSELL L.; THORNBERG, STEVEN M.

    1999-10-01

    Flammable deposits have been analyzed from the exhaust systems of tools employing dichlorosilane (DCS) as a processing gas. Exact mass determinations with a high-resolution Fourier-transform ion-cyclotron resonance (FT-ICR) mass spectrometer allowed the identification of various polysiloxane species present in such an exhaust flow. Ion-molecule reactions indicate the preferred reaction pathway of siloxane formation is through HCl loss, leading to the highly reactive polysiloxane that was detected in the flammable deposits.

  8. Typing Pseudomonas aeruginosa Isolates with Ultrahigh Resolution MALDI-FTICR Mass Spectrometry.

    Science.gov (United States)

    Fleurbaaij, Frank; Kraakman, Margriet E M; Claas, Eric C J; Knetsch, Cornelis W; van Leeuwen, Hans C; van der Burgt, Yuri E M; Veldkamp, Karin Ellen; Vos, Margreet C; Goessens, Wil; Mertens, Bart J; Kuijper, Ed J; Hensbergen, Paul J; Nicolardi, Simone

    2016-06-01

    The introduction of standardized matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) platforms in the medical microbiological practice has revolutionized the way microbial species identification is performed on a daily basis. To a large extent, this is due to the ease of operation. Acquired spectra are compared to profiles obtained from cultured colonies present in a reference spectra database. It is fast and reliable, and costs are low compared to previous diagnostic approaches. However, the low resolution and dynamic range of the MALDI-TOF profiles have shown limited applicability for the discrimination of different bacterial strains, as achieved with typing based on genetic markers. This is pivotal in cases where certain strains are associated with, e.g., virulence or antibiotic resistance. Ultrahigh resolution MALDI-FTICR MS allows the measurement of small proteins at isotopic resolution and can be used to analyze complex mixtures with increased dynamic range and higher precision than MALDI-TOF MS, while still generating results in a similar time frame. Here, we propose to use ultrahigh resolution 15T MALDI-Fourier transform ion cyclotron resonance (FTICR) MS to discriminate clinically relevant bacterial strains after species identification performed by MALDI-TOF MS. We used a collection of well characterized Pseudomonas aeruginosa strains, featuring distinct antibiotic resistance profiles, and isolates obtained during hospital outbreaks. Following cluster analysis based on amplification fragment length polymorphism (AFLP), these strains were grouped into three different clusters. The same clusters were obtained using protein profiles generated by MALDI-FTICR MS. Subsequent intact protein analysis by electrospray ionization (ESI)-collision-induced dissociation (CID)-FTICR MS was applied to identify protein isoforms that contribute to the separation of the different clusters, illustrating the additional advantage of this

  9. FT-ICR studies of anionic reactions for the chemistry of planetary ionospheres

    Czech Academy of Sciences Publication Activity Database

    Romanzin, C.; Louarn, E.; Lemaire, J.; Žabka, Ján; Polášek, Miroslav; Guillemin, J.-C.; Alcaraz, Ch.

    2015-01-01

    Roč. 635, - (2015), 032112. ISSN 1742-6588. [XXIX International Conference on Photonic, Electronic, and Atomic Collisions (ICPEAC2015). 22.07.2015-28.07.2015, Toledo] R&D Projects: GA ČR GAP208/11/0446 Grant ostatní: COST(XE) CM0805 Institutional support: RVO:61388955 Keywords : FT-ICR studies * ionisphere * Titan Subject RIV: CF - Physical ; Theoretical Chemistry

  10. Electrospray ionization FT-ICR mass spectrometry of ARN naphthenic acids in crudes : preconcentration and quantification

    Energy Technology Data Exchange (ETDEWEB)

    Mapolelo, M.M.; Rodgers, R.P.; Marshall, A.G. [Florida State Univ., Tallahassee, FL (United States). Dept. of Chemistry and Biochemistry; Florida State Univ., Tallahassee, FL (United States). Cyclotron Resonance Program, National High Magnetic Field Laboratory

    2008-07-01

    The deposition of naphthenate solids and formation of sodium soaps in oil production equipment are known to create flow assurance problems for oilfield operators. Calcium naphthenate formation depends largely on tetraprotic naphthenic acids known as ARN acids in crude oil, whereas sodium naphthenates originate from less substituted lower molecular weight naphthenic acids. This study attempted to preconcentrate and quantify ARN-type acids in whole crude oils. Fourier transform ion cyclotron resonance (FT-ICR) mass spectroscopy (MS) provided detailed acidic speciation for all crudes and deposits analyzed. The preconcentration step involved bubbling ammonia into toluene-diluted crudes known to have ARN-type acids. ARN acids from the crystals increased from undetectable in the parent crude, to the most abundant acid species in the extract mass spectrum. A pure ARN acid standard was prepared for quantitation from successive cleaning and acid digestion of a naphthenate deposit. Analysis of the standard by negative-ion electrospray ionization (ESI) FT-ICR MS showed only ARN acid species. The paper described how API gravity, solvent systems and the paraffinic versus aromatic composition in the crude oil can influence crystal formation. Correlation of FT-ICR MS data of the respective crudes known to contain ARN acids naturally and crudes spiked with ARN acid standard were discussed and the significance of the preconcentration step was highlighted as a method to enhance the detection of ARN acids in crudes.

  11. ESI FTICR-MS Analysis of Larvae from the Marine Sponge Luffariella variabilis

    Directory of Open Access Journals (Sweden)

    Dianne M. Tapiolas

    2010-01-01

    Full Text Available The viviparous Great Barrier Reef sponge Luffariella variabilis (Poléjaeff 1884 contains a range of secondary metabolites, including manoalide (1 and manoalide monoacetate (3. ESI (+ FTICR-MS accurate mass determination has, for the first time, been used to detected the presence of 3 only in an organic extract of a single L. variabilis larva showing that the parentally produced 3 is sequestered in the larva. As 3 has previously been shown to have antibacterial and quorum sensing inhibition activity, and readily converts to 1, which also exhibits similar activity, it may provide a chemical defence against predation and microbial attack.

  12. Broad-band detection and mass comparison between lithium ions by FT-ICR MS

    Energy Technology Data Exchange (ETDEWEB)

    Golzke, Hendrik [Max-Planck-Institut fuer Kernphysik, Heidelberg (Germany); Institut fuer Experimentelle Kernphysik, Karlsruher Institut fuer Technologie, Karlsruhe (Germany); Blaum, Klaus; Heck, Michael; Ubieto-Diaz, Marta [Max-Planck-Institut fuer Kernphysik, Heidelberg (Germany); Cakirli, R. Burcu [Max-Planck-Institut fuer Kernphysik, Heidelberg (Germany); Department of Physics, University of Istanbul, Istanbul (Turkey); Rodriguez, Daniel [Departamento de Fisica Atomica Molecular y Nuclear, Universidad de Granada, Granada (Spain); Schweikhard, Lutz [Institute of Physics, Ernst-Moritz-Arndt-University Greifswald, Greifswald (Germany); Stahl, Stefan [Stahl Electronics, Kellerweg 23, 67528 Mettenheim (Germany)

    2012-07-01

    Penning traps are widely used as storage devices for charged particles. With such a trap a mass-spectrometry system for the KArlsruhe TRItium Neutrino (KATRIN) experiment has been developed and characterized at the Max-Planck-Institute for Nuclear Physics in Heidelberg. A broad-band non-destructive Fourier Transform Ion Cyclotron Resonance (FT-ICR) method which is able to record simultaneously the eigenfrequencies of different stored particles over a wide range is used. In this talk the dipolar and quadrupolar detection technique and a recent mass comparison between {sup 6}Li{sup +} and {sup 7}Li{sup +} are presented.

  13. Advanced Mass Calibration and Visualization for FT-ICR Mass Spectrometry Imaging

    CERN Document Server

    Smith, Donald F; Konijnenburg, Marco; Klinkert, Ivo; Pasa-Tolic, Ljiljana; Heeren, Ron M A

    2013-01-01

    Mass spectrometry imaging by Fourier transform ion cyclotron resonance yields hundreds of unique peaks, many of which cannot be resolved by lower performance mass spectrometers. The high mass accuracy and high mass resolving power allow confident identification of small molecules and lipids directly from biological tissue sections. Here, calibration strategies for Fourier transform ion cyclotron resonance mass spectrometry imaging were investigated. Sub parts-per-million mass accuracy is demonstrated over an entire tissue section. Ion abundance fluctuations are corrected for by addition of total and relative ion abundances for a root-mean-square error of 0.158 ppm on 16,764 peaks. A new approach for visualization of Fourier transform ion cyclotron resonance mass spectrometry imaging data at high resolution is presented. The Mosaic Data-cube provides a flexible means to visualize the entire mass range at a mass spectral bin width of 0.001 Dalton. The high resolution Mosaic Data-cube resolves spectral features ...

  14. Advanced Mass Calibration and Visualization for FT-ICR Mass Spectrometry Imaging

    OpenAIRE

    Smith, Donald F.; Kharchenko, Andriy; Konijnenburg, Marco; Klinkert, Ivo; Pasa-Tolic, Ljiljana; Ron M A Heeren

    2013-01-01

    Mass spectrometry imaging by Fourier transform ion cyclotron resonance yields hundreds of unique peaks, many of which cannot be resolved by lower performance mass spectrometers. The high mass accuracy and high mass resolving power allow confident identification of small molecules and lipids directly from biological tissue sections. Here, calibration strategies for Fourier transform ion cyclotron resonance mass spectrometry imaging were investigated. Sub parts-per-million mass accuracy is demo...

  15. Dipolar and quadrupolar detection using an FT-ICR MS setup at the MPIK Heidelberg

    Energy Technology Data Exchange (ETDEWEB)

    Heck, Michael, E-mail: michael.heck@mpi-hd.mpg.de; Blaum, Klaus; Cakirli, R. Burcu [Max-Planck-Insitute for Nuclear Physics (Germany); Rodriguez, Daniel [Universidad de Granada (Spain); Schweikhard, Lutz [Ernst-Moritz-Arndt University Greifswald, Institute of Physics (Germany); Stahl, Stefan [Stahl-Electronics (Germany); Ubieto-Diaz, Marta [Max-Planck-Insitute for Nuclear Physics (Germany)

    2011-07-15

    Dipolar and single-phase two-electrode quadrupolar detection schemes have been investigated at a Fourier transform ion cyclotron resonance mass spectrometry (FT-ICR MS) setup built for the KATRIN experiment at the Max-Planck-Institute for Nuclear Physics (MPIK) in Heidelberg. We present first experimental results of {sup 7}Li{sup + } signals from a cylindrical Penning trap configuration for both detection schemes. While the prominent signal of the conventional dipolar detection scheme marks the reduced cyclotron frequency, the main signal for the quadrupolar detection appears at the sum of the reduced cyclotron frequency and the magnetron frequency. For ideal trapping fields, this sum frequency equals the ion cyclotron frequency {nu}{sub c} = qB/(2{pi}m). Sidebands due to the combined motions of the cyclotron mode and magnetron mode are observed by quadrupolar detection which allows the determination of the respective combinations of eigenfrequencies.

  16. Top-Down Mass Spectrometry Imaging of Intact Proteins by LAESI FT-ICR MS

    CERN Document Server

    Kiss, András; Reschke, Brent R; Powell, Matthew J; Heeren, Ron M A

    2013-01-01

    Laser Ablation Electrospray Ionization is a recent development in mass spectrometry imaging. It has been shown that lipids and small metabolites can be imaged in various samples such as plant material, tissue sections or bacterial colonies without anysample pre-treatment. Further, laser ablation electrospray ionization has been shown to produce multiply charged protein ions from liquids or solid surfaces. This presents a means to address one of the biggest challenges in mass spectrometry imaging; the identification of proteins directly from biological tissue surfaces. Such identification is hindered by the lack of multiply charged proteins in common MALDI ion sources and the difficulty of performing tandem MS on such large, singly charged ions. We present here top-down identification of intact proteins from tissue with a LAESI ion source combined with a hybrid ion-trap FT-ICR mass spectrometer. The performance of the system was first tested with a standard protein with ECD and IRMPD fragmentation to prove the...

  17. An investigation of emulsion interfacial material by ultrahigh resolution FT-ICR mass spectrometry

    Energy Technology Data Exchange (ETDEWEB)

    Ehrmann, B.M. [Florida State Univ., Tallahassee, FL (United States). Dept. of Chemistry and Biochemistry; Juyal, P. [Florida State Univ., Tallahassee, FL (United States). National High Magnetic Field Laboratory; Rodgers, R.P.; Marshall, A.G. [Florida State Univ., Tallahassee, FL (United States). Dept. of Chemistry and Biochemistry; Florida State Univ., Tallahassee, FL (United States). National High Magnetic Field Laboratory

    2008-07-01

    The formation of water-oil emulsions in crude oil poses a large problem for the petroleum industry because of the production losses and cost associated with chemicals used to break the emulsions. The species responsible for emulsion formation must therefore be identified and characterized. It has been suggested that asphaltenes absorb and accumulate at the emulsion water-oil interface and contribute to emulsion stability. However, studies have also shown that co-precipitated material may contribute to the stability of the water-oil emulsions. Fourier transform ion cyclotron resonance (FT-ICR) mass spectroscopy (MS) analysis of the acidic portion of interfacial material has revealed that it is also enriched in specific Ox and SOx species relative to the parent crude. The similarity between the co-precipitate and isolated interfacial material suggests that naphthenic acids strongly interact with the asphaltenes. As a result, they co-precipitate with them even though naphthenic acids alone are soluble in n-heptane. This study characterized the interfacial material and a crude oil known to cause emulsions in the field. The basic, acidic, and aromatic species in the isolated interfacial material and parent crude were highlighted by positive/negative electrospray ionization and atmospheric pressure photoionization (APPI) high resolution Fourier transform ion cyclotron resonance (FT-ICR) mass spectrometry. The composition of the interfacial material was also investigated. An attempt was made to regenerate the emulsion after isolation, in the absence of the parent crude. Once the emulsion was formed, the isolated interfacial material was analyzed to determine the minimum components required to form a stable emulsion. This provided a direct comparison between the species identified in the interfacial material and those that interact with the asphaltene fraction of the crude oil.

  18. High Mass Accuracy and High Mass Resolving Power FT-ICR Secondary Ion Mass Spectrometry for Biological Tissue Imaging

    CERN Document Server

    Smith, Donald F; Leach, Franklin E; Robinson, Errol W; Paša-Tolić, Ljiljana; Heeren, Ron M A

    2013-01-01

    Biological tissue imaging by secondary ion mass spectrometry has seen rapid development with the commercial availability of polyatomic primary ion sources. Endogenous lipids and other small bio-molecules can now be routinely mapped on the sub-micrometer scale. Such experiments are typically performed on time-of-flight mass spectrometers for high sensitivity and high repetition rate imaging. However, such mass analyzers lack the mass resolving power to ensure separation of isobaric ions and the mass accuracy for elemental formula assignment based on exact mass measurement. We have recently reported a secondary ion mass spectrometer with the combination of a C60 primary ion gun with a Fourier transform ion cyclotron resonance mass spectrometer (FT-ICR MS) for high mass resolving power, high mass measurement accuracy and tandem mass spectrometry capabilities. In this work, high specificity and high sensitivity secondary ion FT-ICR MS was applied to chemical imaging of biological tissue. An entire rat brain tissu...

  19. TG/DTG, FT-ICR Mass Spectrometry, and NMR Spectroscopy Study of Heavy Fuel Oil

    KAUST Repository

    Elbaz, Ayman M.

    2015-11-12

    There is an increasing interest in the comprehensive study of heavy fuel oil (HFO) due to its growing use in furnaces, boilers, marines, and recently in gas turbines. In this work, the thermal combustion characteristics and chemical composition of HFO were investigated using a range of techniques. Thermogravimetric analysis (TGA) was conducted to study the nonisothermal HFO combustion behavior. Chemical characterization of HFO was accomplished using various standard methods in addition to direct infusion atmospheric pressure chemical ionization Fourier transform ion cyclotron resonance mass spectrometry (APCI-FTICR MS), high resolution 1H nuclear magnetic resonance (NMR), 13C NMR, and two-dimensional heteronuclear multiple bond correlation (HMBC) spectroscopy. By analyzing thermogravimetry and differential thermogravimetry (TG/DTG) results, three different reaction regions were identified in the combustion of HFO with air, specifically, low temperature oxidation region (LTO), fuel deposition (FD), and high temperature oxidation (HTO) region. At the high end of the LTO region, a mass transfer resistance (skin effect) was evident. Kinetic analysis in LTO and HTO regions was conducted using two different kinetic models to calculate the apparent activation energy. In both models, HTO activation energies are higher than those for LTO. The FT-ICR MS technique resolved thousands of aromatic and sulfur containing compounds in the HFO sample and provided compositional details for individual molecules of three major class species. The major classes of compounds included species with one sulfur atom (S1), with two sulfur atoms (S2), and purely hydrocarbons (HC). The DBE (double bond equivalent) abundance plots established for S1 and HC provided additional information on their distributions in the HFO sample. The 1H NMR and 13C NMR results revealed that nearly 59% of the 1H nuclei were distributed as paraffinic CH2 and 5% were in aromatic groups. Nearly 21% of 13C nuclei were

  20. Compositional analysis of heavy crude oil fractions by ultrahigh resolution FT-ICR mass spectrometry

    Energy Technology Data Exchange (ETDEWEB)

    Rodgers, R.; Marshall, A.G. [Florida State Univ., Tallahassee, FL (United States). Dept. of Chemistry; Florida State Univ., Tallahassee, FL (United States). National High Magnetic Field Lab; McKenna, A.M. [Florida State Univ., Tallahassee, FL (United States). Dept. of Chemistry

    2009-07-01

    The need to characterize heavy, high sulphur crudes is essential as the global oil supply of light, sweet crudes is depleted. Due to the high sulphur content in bitumen and heavy crudes, detailed compositional characterization is needed to help develop recovery strategies in the refinery. This study characterized the middle distillate fractions of Athabasca bitumen to define the structural evolution of polycyclic aromatics that may also contain nitrogen, oxygen or sulphur atoms as a function of boiling point. The higher distillate fractions were then analyzed along with vacuum resids to prove that the structural distribution in petroleum is continuous. The basic differences in solution-phase behaviour between asphaltene and maltene fractions were discussed. An argument was presented for the structural evolution of polyaromatic hydrocarbons, and the compositional boundary between asphaltene and maltene was defined. The study suggested that asphaltenes and maltenes share the same carbon number. The characterization was extended to vanadyl porphyrins by electrospray and atmospheric pressure photoionization Fourier transform ion cyclotron resonance mass spectrometry (FT-ICR MS). tabs., figs.

  1. High field FT-ICR mass spectrometry for molecular characterization of snow board from Moscow regions.

    Science.gov (United States)

    Mazur, Dmitry M; Harir, Mourad; Schmitt-Kopplin, Philippe; Polyakova, Olga V; Lebedev, Albert T

    2016-07-01

    High field Fourier transform ion cyclotron resonance (FT-ICR) mass spectrometry analysis of eight snow samples from Moscow city allowed us to identify more than 2000 various elemental compositions corresponding to regional air pollutants. The hierarchical cluster analysis (HCA) of the data showed good concordance of three main groups of samples with the main wind directions. The North-West group (A1) is represented by several homologous CHOS series of aliphatic organic aerosols. They may form as a result of enhanced photochemical reactions including oxidation of hydrocarbons with sulfonations due to higher amount of SO2 emissions in the atmosphere in this region. Group A2, corresponding to the South-East part of Moscow, contains large amount of oxidized hydrocarbons of different sources that may form during oxidation in atmosphere. These hydrocarbons appear correlated to emissions from traffic, neighboring oil refinery, and power plants. Another family of compounds specific for this region involves CHNO substances formed during oxidation processes including NOx and NO3 radical since emissions of NOx are higher in this part of the city. Group A3 is rich in CHO type of compounds with high H/C and low O/C ratios, which is characteristic of oxidized hydrocarbon-like organic aerosol. CHNO types of compounds in A3 group are probably nitro derivatives of condensed hydrocarbons such as PAH. This non-targeted profiling revealed site specific distribution of pollutants and gives a chance to develop new strategies in air quality control and further studies of Moscow environment. PMID:26994789

  2. Nano-LC FTICR tandem mass spectrometry for top-down proteomics: routine baseline unit mass resolution of whole cell lysate proteins up to 72 kDa.

    Science.gov (United States)

    Tipton, Jeremiah D; Tran, John C; Catherman, Adam D; Ahlf, Dorothy R; Durbin, Kenneth R; Lee, Ji Eun; Kellie, John F; Kelleher, Neil L; Hendrickson, Christopher L; Marshall, Alan G

    2012-03-01

    Current high-throughput top-down proteomic platforms provide routine identification of proteins less than 25 kDa with 4-D separations. This short communication reports the application of technological developments over the past few years that improve protein identification and characterization for masses greater than 25 kDa. Advances in separation science have allowed increased numbers of proteins to be identified, especially by nanoliquid chromatography (nLC) prior to mass spectrometry (MS) analysis. Further, a goal of high-throughput top-down proteomics is to extend the mass range for routine nLC MS analysis up to 80 kDa because gene sequence analysis predicts that ~70% of the human proteome is transcribed to be less than 80 kDa. Normally, large proteins greater than 50 kDa are identified and characterized by top-down proteomics through fraction collection and direct infusion at relatively low throughput. Further, other MS-based techniques provide top-down protein characterization, however at low resolution for intact mass measurement. Here, we present analysis of standard (up to 78 kDa) and whole cell lysate proteins by Fourier transform ion cyclotron resonance mass spectrometry (nLC electrospray ionization (ESI) FTICR MS). The separation platform reduced the complexity of the protein matrix so that, at 14.5 T, proteins from whole cell lysate up to 72 kDa are baseline mass resolved on a nano-LC chromatographic time scale. Further, the results document routine identification of proteins at improved throughput based on accurate mass measurement (less than 10 ppm mass error) of precursor and fragment ions for proteins up to 50 kDa. PMID:22356091

  3. MALDI-FTICR MS Imaging as a Powerful Tool to Identify Paenibacillus Antibiotics Involved in the Inhibition of Plant Pathogens

    Science.gov (United States)

    Debois, Delphine; Ongena, Marc; Cawoy, Hélène; De Pauw, Edwin

    2013-08-01

    Nowadays, microorganisms are more and more often used as biocontrol agents for crop protection against diseases. Among them, bacteria of Bacillus and Paenibacillus genders are already used as commercial biocontrol agents. Their mode of action is supposed to be related to their production of antibiotics, such as cyclic lipopeptides, which exhibit great antimicrobial activities. We chose to work with a Paenibacillus polymyxa strain (Pp56) very resistant to various microorganisms. The bacteria were grown simultaneously with Fusarium oxysporum and we applied matrix-assisted laser desorption/ionization-Fourier transform ion cyclotron resonance (MALDI-FTICR) mass spectrometry to identify the antibiotics compounds present in the fungus growth inhibition area. We, therefore, identified fusaricidins A, B, and C and numerous members of the LI-F antibiotics family. MALDI-FTICR mass spectrometry imaging was then used to follow the diffusion of lipopeptides involved in the inhibitory activity over time. We analyzed the molecular content of the inhibitory area at different Pp56 and Fusarium incubation durations and concluded that some lipopeptides such as fusaricidin B and a mixture of LI-F05b/06b/08a were mainly involved in the defense mechanism of Pp56. Our study confirms that MALDI imaging may be a powerful tool to quickly determine which molecular species is involved in an antagonism with another microorganism, avoiding time-consuming steps of extraction, purification, and activity tests, which are still commonly used in microbiology.

  4. Gas Chromatography Coupled to Atmospheric Pressure Chemical Ionization FT-ICR Mass Spectrometry for Improvement of Data Reliability.

    Science.gov (United States)

    Schwemer, Theo; Rüger, Christopher P; Sklorz, Martin; Zimmermann, Ralf

    2015-12-15

    Atmospheric pressure chemical ionization (APCI) offers the advantage of molecular ion information with low fragmentation. Hyphenating APCI to gas chromatography (GC) and ultrahigh resolution mass spectrometry (FT-ICR MS) enables an improved characterization of complex mixtures. Data amounts acquired by this system are very huge, and existing peak picking algorithms are usually extremely time-consuming, if both gas chromatographic and ultrahigh resolution mass spectrometric data are concerned. Therefore, automatic routines are developed that are capable of handling these data sets and further allow the identification and removal of known ionization artifacts (e.g., water- and oxygen-adducts, demethylation, dehydrogenation, and decarboxylation). Furthermore, the data quality is enhanced by the prediction of an estimated retention index, which is calculated simply from exact mass data combined with a double bond equivalent correction. This retention index is used to identify mismatched elemental compositions. The approach was successfully tested for analysis of semivolatile components in heavy fuel oil and diesel fuel as well as primary combustion particles emitted by a ship diesel research engine. As a result, 10-28% of the detected compounds, mainly low abundant species, classically assigned by using only the mass spectrometric information, were identified as not valid and removed. Although GC separation is limited by the slow acquisition rate of the FT-ICR MS (<1 Hz), a database driven retention time comparison, as commonly used for low resolution GC/MS, can be applied for revealing isomeric information. PMID:26560682

  5. Spatial Segmentation of MALDI FT-ICR MSI Data: A Powerful Tool to Explore the Head and Neck Tumor In Situ Lipidome

    Czech Academy of Sciences Publication Activity Database

    Krásný, Lukáš; Hoffmann, F.; Ernst, G.; Trede, D.; Alexandrov, T.; Havlíček, Vladimír; Guntinas-Lichius, O.; von Eggeling, F.; Crecelius, A.C.

    2015-01-01

    Roč. 26, č. 1 (2015), s. 36-43. ISSN 1044-0305 R&D Projects: GA MŠk(CZ) LD13038 Institutional support: RVO:61388971 Keywords : MALDI * MSI * FT-ICR Subject RIV: CE - Biochemistry Impact factor: 2.945, year: 2014

  6. Characterization of dissolved organic nitrogen in wet deposition from Lake Erhai basin by using ultrahigh resolution FT-ICR mass spectrometry.

    Science.gov (United States)

    Feng, Shuang; Zhang, Li; Wang, Shengrui; Nadykto, Alexey B; Xu, Yisheng; Shi, Quan; Jiang, Bin; Qian, Weibin

    2016-08-01

    Dissolved Organic Nitrogen (DON) of wet deposition in Erhai basin (EWD) was characterized at the molecular level by using electrospray ionization Fourier transform ion cyclotron resonance mass spectrometry (ESI FT-ICR MS). The structure and composition of DON were investigated by the combined ESI FT-ICR MS, UV-Vis absorbance and fluorescence techniques. The FT-ICR MS measurements indicate that a large (∼790) number of organic species present in the wet deposition, in which DON account for 18.3%, with most of DON containing a single nitrogen atom. The typical relative molecular mass of the DON species was found to be in the range of 200-400 Da. Approximately 57.2% of DON species are highly unsaturated (DBE (Double Bond Equivalent) > 5) with the nitrogen- and sulfur-containing species, which are probably represented mainly by active nitrooxy organosulfates, accounting for ∼ 19.3% of the total DON. The low average SUVA254 and A253/A203 values (0.02 and 0.06, respectively), indicates that the aromaticity of the EWD samples is particularly weak. The average values of E2/E3 and E4/E6 in the EWD samples were 6.84 and 1.84, respectively. This is a clear indication of the low degree of humification of EWD samples, in agreement with ESI FT-ICR MS measurements. Our study demonstrates that multiple experimental techniques combined with FT-ICR MS, UV-Vis absorbance and fluorescence can be efficiently used for in-depth studying the DON at the molecular level. Thus it allows us to achieve a deep and insightful understanding of the DON structure and composition. PMID:27192481

  7. On-Line Electrochemical Reduction of Disulfide Bonds: Improved FTICR-CID and -ETD Coverage of Oxytocin and Hepcidin

    Science.gov (United States)

    Nicolardi, Simone; Giera, Martin; Kooijman, Pieter; Kraj, Agnieszka; Chervet, Jean-Pierre; Deelder, André M.; van der Burgt, Yuri E. M.

    2013-12-01

    Particularly in the field of middle- and top-down peptide and protein analysis, disulfide bridges can severely hinder fragmentation and thus impede sequence analysis (coverage). Here we present an on-line/electrochemistry/ESI-FTICR-MS approach, which was applied to the analysis of the primary structure of oxytocin, containing one disulfide bridge, and of hepcidin, containing four disulfide bridges. The presented workflow provided up to 80 % (on-line) conversion of disulfide bonds in both peptides. With minimal sample preparation, such reduction resulted in a higher number of peptide backbone cleavages upon CID or ETD fragmentation, and thus yielded improved sequence coverage. The cycle times, including electrode recovery, were rapid and, therefore, might very well be coupled with liquid chromatography for protein or peptide separation, which has great potential for high-throughput analysis.

  8. Rapid and automated processing of MALDI-FTICR/MS data for 15N-metabolic labeling in a shotgun proteomics analysis

    Science.gov (United States)

    Jing, Li; Amster, I. Jonathan

    2009-10-01

    Offline high performance liquid chromatography combined with matrix assisted laser desorption and Fourier transform ion cyclotron resonance mass spectrometry (HPLC-MALDI-FTICR/MS) provides the means to rapidly analyze complex mixtures of peptides, such as those produced by proteolytic digestion of a proteome. This method is particularly useful for making quantitative measurements of changes in protein expression by using 15N-metabolic labeling. Proteolytic digestion of combined labeled and unlabeled proteomes produces complex mixtures with many mass overlaps when analyzed by HPLC-MALDI-FTICR/MS. A significant challenge to data analysis is the matching of pairs of peaks which represent an unlabeled peptide and its labeled counterpart. We have developed an algorithm and incorporated it into a computer program which significantly accelerates the interpretation of 15N-metabolic labeling data by automating the process of identifying unlabeled/labeled peak pairs. The algorithm takes advantage of the high resolution and mass accuracy of FTICR mass spectrometry. The algorithm is shown to be able to successfully identify the 15N/14N peptide pairs and calculate peptide relative abundance ratios in highly complex mixtures from the proteolytic digest of a whole organism protein extract.

  9. Utilizing a Robotic Sprayer for High Lateral and Mass Resolution MALDI FT-ICR MSI of Microbial Cultures

    Science.gov (United States)

    Anderton, Christopher R.; Chu, Rosalie K.; Tolić, Nikola; Creissen, Alain; Paša-Tolić, Ljiljana

    2016-03-01

    The ability to visualize biochemical interactions between microbial communities using MALDI MSI has provided tremendous insights into a variety of biological fields. Matrix application using a sieve proved to be incredibly useful, but it has many limitations that include uneven matrix coverage and limitation in the types of matrices that could be employed in studies. Recently, there has been a concerted effort to improve matrix application for studying agar plated microbial cultures, many of which utilized automated matrix sprayers. Here, we describe the usefulness of using a robotic sprayer for matrix application. The robotic sprayer has two-dimensional control over where matrix is applied, and a heated capillary that allows for rapid drying of the applied matrix. This method provided a significant increase in MALDI sensitivity over the sieve method, as demonstrated by FT-ICR MS analysis, facilitating the ability to gain higher lateral resolution MS images of Bacillus subtilis than previously reported. This method also allowed for the use of different matrices to be applied to the culture surfaces.

  10. Utilizing a Robotic Sprayer for High Lateral and Mass Resolution MALDI FT-ICR MSI of Microbial Cultures

    Energy Technology Data Exchange (ETDEWEB)

    Anderton, Christopher R.; Chu, Rosalie K.; Tolic, Nikola; Creissen, Alain V.; Pasa-Tolic, Ljiljana

    2016-01-07

    The ability to visualize biochemical interactions between microbial communities using MALDI MSI has provided tremendous insights into a variety of biological fields. Matrix application using a sieve proved to be incredibly useful, but it had many limitations that include uneven matrix coverage and limitation in the types of matrices one could employ in their studies. Recently, there has been a concerted effort to improve matrix application for studying agar plated microbial cultures, many of which utilized automated matrix sprayers. Here, we describe the usefulness of using a robotic sprayer for matrix application. The robotic sprayer has two-dimensional control over where matrix is applied and a heated capillary that allows for rapid drying of the applied matrix. This method provided a significant increase in MALDI sensitivity over the sieve method, as demonstrated by FT-ICR MS analysis, facilitating the ability to gain higher lateral resolution MS images of Bacillus Subtilis than previously reported. This method also allowed for the use of different matrices to be applied to the culture surfaces.

  11. High molecular weight SOA formation during limonene ozonolysis: insights from ultrahigh-resolution FT-ICR mass spectrometry characterization

    Science.gov (United States)

    Kundu, S.; Fisseha, R.; Putman, A. L.; Rahn, T. A.; Mazzoleni, L. R.

    2012-06-01

    The detailed molecular composition of laboratory generated limonene ozonolysis secondary organic aerosol (SOA) was studied using ultrahigh-resolution Fourier transform ion cyclotron resonance (FT-ICR) mass spectrometry. Approximately 1200 molecular formulas were identified in the SOA over the mass range of 140 to 850 Da. Four characteristic groups of high relative abundance species were observed; they indicate an array of accretion products that retain a large fraction of the limonene skeleton. The identified molecular formulas of each of the groups are related to one another by CH2, O and CH2O homologous series. The CH2 and O homologous series of the low molecular weight (MW) SOA (m/z 300) were found to constitute a significant number fraction of the identified SOA components. The formation of high MW compounds was evaluated by molecular formula trends, fragmentation analysis of select high MW compounds and a comprehensive reaction matrix including the identified low MW SOA, hydroperoxides and Criegee radicals as building blocks. Although the formation of high MW SOA may occur via a variety of radical and non-radical reaction channels, the combined approach indicates a greater importance of the non-condensation reactions over aldol and ester condensation reaction channels. Among these hemi-acetal reactions appear to be most dominant followed by hydroperoxide and Criegee reaction channels.

  12. Atmospheric organic matter in clouds: exact masses and molecular formula identification using ultrahigh resolution FT-ICR mass spectrometry

    Science.gov (United States)

    Zhao, Y.; Hallar, A. G.; Mazzoleni, L. R.

    2013-08-01

    cyclotron resonance (FT-ICR) mass spectrometry provides an unambiguous identification of the cloud water organic composition in the Rocky Mountain area which could help to improve the understanding of aqueous phase processes.

  13. Exploring Biosignatures Associated with Thenardite by Geomatrix-Assisted Laser Desorption/Ionization Fourier Transform Ion Cyclotron Resonance Mass Spectrometry (GALDI-FTICR-MS)

    Energy Technology Data Exchange (ETDEWEB)

    C. Doc Richardson; Nancy W. Hinman; Timothy R. McJunkin; J. Michelle Kotler; Jill R. Scott

    2008-10-01

    Geomatrix-assisted laser desorption/ionization (GALDI) in conjunction with a Fourier transform ion cyclotron resonance mass spectrometer (FTICR-MS) has been employed to determine how effectively bio/organic molecules associated with the mineral thenardite (Na2SO4) can be detected. GALDI is based on the ability of the mineral host to assist desorption and ionization of bio/organic molecules without additional sample preparation. When glycine was mixed with thenardite, glycine was deprotonated to produce C2H4NO-2 at m/z 74.025. The combination of stearic acid with thenardite produced a complex cluster ion at m/z 390.258 in the negative mode, which was assigned a composition ofC18H39O7Na-. Anatural sample of thenardite from Searles Lake in California also produced a peak at m/z 390.260. The bio/organic signatures in both the laboratory-based and natural samples were heterogeneously dispersed as revealed by chemical imaging. The detection limits for the stearic acid and thenardite combination were estimated to be 3 parts per trillion or~7 zeptomoles (10-21) per laser spot. Attempts to improve the signal-to-noise ratio by co-adding FTICR-MS data predetermined to contain the biosignatures of interest revealed problems due to a lack of phase coherence between data sets.

  14. Detection of phosphorylated subunits by combined LA-ICP-MS and MALDI-FTICR-MS analysis in yeast mitochondrial membrane complexes separated by blue native/SDS-PAGE

    Science.gov (United States)

    Krause-Buchholz, Udo; Becker, J. Susanne; Zoriy, Miroslav; Pickhardt, Carola; Przybylski, Michael; Rödel, Gerhard; Becker, J. Sabine

    2006-01-01

    We report on the identification of phosphorylated subunits of yeast mitochondrial ATPase using a novel screening technique in combination with BN/SDS-PAGE. Protein complexes present in yeast mitochondrial membranes were separated in their native state in the first dimension and their subunit composition was resolved by SDS-PAGE in the second dimension. Laser ablation inductively coupled plasma mass spectrometry (LA-ICP-MS) was used to rapidly screen for the presence of phosphorus in the subunits. The detection limits of elements investigated in selected protein spots are in the low [mu]g g-1 concentration range. Sulfur was used as the internal standard element for quantification. Phosphorus was detected in two of the proteins, that were identified by matrix-assisted laser desorption/ionization Fourier transform ion cyclotron resonance mass spectrometry (MALDI-FTICR-MS) as subunits Atp1p and Atp2p of the ATPase. These results were confirmed by Western blot analysis using antibodies directed against phosphorylated amino acids. The combination of LA-ICP-MS and MALDI-FTICR-MS with BN/SDS-PAGE provides a fast and sensitive tool for structure analysis of phosphorus and metal-containing subunits of membrane protein complexes.

  15. High molecular weight SOA formation during limonene ozonolysis: insights from ultrahigh-resolution FT-ICR mass spectrometry characterization

    Directory of Open Access Journals (Sweden)

    S. Kundu

    2012-01-01

    Full Text Available The detailed molecular composition of secondary organic aerosols (SOA from limonene ozonolysis was studied using ultrahigh-resolution Fourier transform ion cyclotron resonance (FT-ICR mass spectrometry. High molecular weight (MW compounds (m/z > 300 were found to constitute a significant number fraction of the identified SOA components. Double bond equivalents (DBE = the number of rings plus the number of double bonds increased with MW. The O:C ratios and relative abundances of compounds decreased with increasing MW. The mass spectra of limonene contain 4 distinct clusters of negative ions: Group I (140 < m/z < 300, Group II (300 < m/z < 500, Group III (500 < m/z < 700 and Group IV (700 < m/z < 850. A number of CH2 and O homologous series of low MW SOA (Group 1 with carbon number 7–15 and oxygen number 3–9 were observed. Their occurrence can be explained with isomerization and elimination reactions of Criegee radicals, reactions between alkyl peroxy radicals, and scission of alkoxy radicals resulting from the Criegee radicals. Additionally, fragmentation analysis and observations of formaldehyde homologous series provide evidence for aerosol growth by the reactive uptake of generated gas-phase carbonyls in limonene ozonolysis. The decreasing O:C ratios between group of compounds indicated the importance of condensation (aldol and esterification reaction pathways for high MW compound formation. However, the prominent DBE changes of 2 between the groups of compounds and selected fragmentation (MS/MS analysis of Group II and Group III ions indicated a predominance of non-condensation (hydroperoxide, Criegee and hemi-acetal reaction pathways. A reaction matrix created with the combination of low MW SOA, hydroperoxides, and Criegee radicals indicated higher frequencies for the hemi-acetal and condensation reaction pathways. Overall, the combined approach confirms the importance of non

  16. High molecular weight SOA formation during limonene ozonolysis: insights from ultrahigh-resolution FT-ICR mass spectrometry characterization

    Directory of Open Access Journals (Sweden)

    S. Kundu

    2012-06-01

    Full Text Available The detailed molecular composition of laboratory generated limonene ozonolysis secondary organic aerosol (SOA was studied using ultrahigh-resolution Fourier transform ion cyclotron resonance (FT-ICR mass spectrometry. Approximately 1200 molecular formulas were identified in the SOA over the mass range of 140 to 850 Da. Four characteristic groups of high relative abundance species were observed; they indicate an array of accretion products that retain a large fraction of the limonene skeleton. The identified molecular formulas of each of the groups are related to one another by CH2, O and CH2O homologous series. The CH2 and O homologous series of the low molecular weight (MW SOA (m/z < 300 are explained with a combination of functionalization and fragmentation of radical intermediates and reactive uptake of gas-phase carbonyls. They include isomerization and elimination reactions of Criegee radicals, reactions between alkyl peroxy radicals, and scission of alkoxy radicals resulting from the Criegee radicals. The presence of compounds with 10–15 carbon atoms in the first group (e.g. C11H18O6 provides evidence for SOA formation by the reactive uptake of gas-phase carbonyls during limonene ozonolysis. The high MW compounds (m/z > 300 were found to constitute a significant number fraction of the identified SOA components. The formation of high MW compounds was evaluated by molecular formula trends, fragmentation analysis of select high MW compounds and a comprehensive reaction matrix including the identified low MW SOA, hydroperoxides and Criegee radicals as building blocks. Although the formation of high MW SOA may occur via a variety of radical and non-radical reaction channels, the combined approach indicates a greater importance of the non-condensation reactions over aldol and ester condensation reaction channels. Among these hemi-acetal reactions appear to be most

  17. Atmospheric organic matter in clouds: exact masses and molecular formula identification using ultrahigh-resolution FT-ICR mass spectrometry

    Science.gov (United States)

    Zhao, Y.; Hallar, A. G.; Mazzoleni, L. R.

    2013-12-01

    cyclotron resonance (FT-ICR) mass spectrometry provides an unambiguous identification of the cloud water organic anion composition in the Rocky Mountain area that could help to improve the understanding of aqueous-phase processes.

  18. Use of ESI-FTICR-MS to Characterize Dissolved Organic Matter in Headwater Streams Draining Forest-Dominated and Pasture-Dominated Watersheds.

    Directory of Open Access Journals (Sweden)

    YueHan Lu

    Full Text Available Electrospray ionization Fourier transform ion cyclotron resonance mass spectrometry (ESI-FTICR-MS has proven to be a powerful technique revealing complexity and diversity of natural DOM molecules, but its application to DOM analysis in grazing-impacted agricultural systems remains scarce. In the present study, we presented a case study of using ESI-FTICR-MS in analyzing DOM from four headwater streams draining forest- or pasture-dominated watersheds in Virginia, USA. In all samples, most formulas were CHO compounds (71.8-87.9%, with other molecular series (CHOS, CHON, CHONS, and CHOP (N, S accounting for only minor fractions. All samples were dominated by molecules falling in the lignin-like region (H/C = 0.7-1.5, O/C = 0.1-0.67, suggesting the predominance of allochthonous, terrestrial plant-derived DOM. Relative to the two pasture streams, DOM formulas in the two forest streams were more similar, based on Jaccard similarity coefficients and nonmetric multidimensional scaling calculated from Bray-Curtis distance. Formulas from the pasture streams were characterized by lower proportions of aromatic formulas and lower unsaturation, suggesting that the allochthonous versus autochthonous contributions of organic matter to streams were modified by pasture land use. The number of condensed aromatic structures (CAS was higher for the forest streams, which is possibly due to the controlled burning in the forest-dominated watersheds and suggests that black carbon was mobilized from soils to streams. During 15-day biodegradation experiments, DOM from the two pasture streams was altered to a greater extent than DOM from the forest streams, with formulas with H/C and O/C ranges similar to protein (H/C = 1.5-2.2, O/C = 0.3-0.67, lipid (H/C = 1.5-2.0, O/C = 0-0.3, and unsaturated hydrocarbon (H/C = 0.7-1.5, O/C = 0-0.1 being the most bioreactive groups. Aromatic compound formulas including CAS were preferentially removed during combined light

  19. Functional Groups and Structural Insights of Water-Soluble Organic Carbon using Ultrahigh Resolution FT-ICR Tandem Mass Spectrometry

    Science.gov (United States)

    Mazzoleni, L. R.; Habib, D.; Zhao, Y.; Dalbec, M.; Samburova, V.; Hallar, G.; Zielinska, B.; Lowenthal, D.

    2013-12-01

    Water-soluble organic carbon (WSOC) is a complex mixture of thousands of organic compounds which may have significant influence on the climate-relevant properties of atmospheric aerosols. An improved understanding of the molecular composition of WSOC is needed to evaluate the effect of aerosol composition upon aerosol physical properties. Products of gas phase, aqueous phase and particle phase reactions contribute to pre-existing aerosol organic mass or nucleate new aerosol particles. Thus, ambient aerosols carry a complex array of WSOC components with variable chemical signatures depending upon its origin and aerosol life-cycle processes. In this work, ultrahigh resolution Fourier transform ion cyclotron resonance mass spectrometry (FT-ICR MS) was used to characterize aerosol WSOC collected during the summer of 2010 at the Storm Peak Laboratory (3210 m a.s.l.) near Steamboat Springs, CO. Approximately 4000 molecular formulas were assigned in the mass range of m/z 100-800 after negative-ion electrospray ionization. The observed trends indicate significant non-oxidative accretion reaction pathways for the formation of high molecular weight WSOC components closely associated with terpene ozonolysis secondary organic aerosol (SOA). The aerosol WSOC was further characterized using ultrahigh resolution tandem MS analysis with infrared multiphoton dissociation to determine the functional groups and structural properties of 1700 WSOC species up to m/z 600. Due to the complex nature of the WSOC, multiple precursor ions were simultaneously fragmented. The exact mass measurements of the precursor and product ions facilitated molecular formula assignments and matching of neutral losses. The most important neutral losses are CO2, H2O, CH3OH, HNO3, CH3NO3, SO3 and SO4. The presence and frequency of these losses indicate the type of functional groups contained in the precursor structures. Consistent with the acidic nature of WSOC compounds, the most frequently observed losses

  20. Epitope mapping of 7S cashew antigen in complex with antibody by solution-phase H/D exchange monitored by FT-ICR mass spectrometry.

    Science.gov (United States)

    Guan, Xiaoyan; Noble, Kyle A; Tao, Yeqing; Roux, Kenneth H; Sathe, Shridhar K; Young, Nicolas L; Marshall, Alan G

    2015-06-01

    The potential epitope of a recombinant food allergen protein, cashew Ana o 1, reactive to monoclonal antibody, mAb 2G4, has been mapped by solution-phase amide backbone H/D exchange (HDX) monitored by Fourier transform ion cyclotron resonance mass spectrometry (FT-ICR MS). Purified mAb 2G4 was incubated with recombinant Ana o 1 (rAna o 1) to form antigen:monoclonal antibody (Ag:mAb) complexes. Complexed and uncomplexed (free) rAna o 1 were then subjected to HDX-MS analysis. Five regions protected from H/D exchange upon mAb binding are identified as potential conformational epitope-contributing segments. PMID:26169135

  1. Rapid Screening for Potential Epitopes Reactive with a Polycolonal Antibody by Solution-Phase H/D Exchange Monitored by FT-ICR Mass Spectrometry

    Science.gov (United States)

    Zhang, Qian; Noble, Kyle A.; Mao, Yuan; Young, Nicolas L.; Sathe, Shridhar K.; Roux, Kenneth H.; Marshall, Alan G.

    2013-07-01

    The potential epitopes of a recombinant food allergen protein, cashew Ana o 2, reactive to polyclonal antibodies, were mapped by solution-phase amide backbone H/D exchange (HDX) coupled with Fourier transform ion cyclotron resonance mass spectrometry (FT-ICR MS). Ana o 2 polyclonal antibodies were purified in the serum from a goat immunized with cashew nut extract. Antibodies were incubated with recombinant Ana o 2 (rAna o 2) to form antigen:polyclonal antibody (Ag:pAb) complexes. Complexed and uncomplexed (free) rAna o 2 were then subjected to HDX-MS analysis. Four regions protected from H/D exchange upon pAb binding are identified as potential epitopes and mapped onto a homologous model.

  2. High-Throughput Proteomics Using High Efficiency Multiple-Capillary Liquid Chromatography With On-Line High-Performance ESI FTICR Mass Spectrometry

    Energy Technology Data Exchange (ETDEWEB)

    Shen, Yufeng (BATTELLE (PACIFIC NW LAB)); Tolic, Nikola (BATTELLE (PACIFIC NW LAB)); Zhao, Rui (ASSOC WESTERN UNIVERSITY); Pasa Tolic, Ljiljana (BATTELLE (PACIFIC NW LAB)); Li, Lingjun (Illinois Univ Of-Urbana/Champa); Berger, Scott J.(ASSOC WESTERN UNIVERSITY); Harkewicz, Richard (BATTELLE (PACIFIC NW LAB)); Anderson, Gordon A.(BATTELLE (PACIFIC NW LAB)); Belov, Mikhail E.(BATTELLE (PACIFIC NW LAB)); Smith, Richard D.(BATTELLE (PACIFIC NW LAB))

    2000-12-01

    We report on the design and application of a high-efficiency multiple-capillary liquid chromatography (LC) system for high-throughput proteome analysis. The multiple-capillary LC system was operated at the pressure of 10,000 psi using commercial LC pumps to deliver the mobile phase and newly developed passive feedback valves to switch the mobile phase flow and introduce samples. The multiple-capillary LC system was composed of several serially connected dual-capillary column devices. The dual-capillary column approach was designed to eliminate the time delay for regeneration (or equilibrium) of the capillary column after its use under the mobile phase gradient condition (i.e. one capillary column was used in separation and the other was washed using mobile phase A). The serially connected dual-capillary columns and ESI sources were operated independently, and could be used for either''backup'' operation or with other mass spectrometer(s). This high-efficiency multiple-capillary LC system uses switching valves for all operations and is highly amenable to automation. The separations efficiency of dual-capillary column device, optimal capillary dimensions (column length and packed particle size), suitable mobile phases for electrospray, and the capillary re-generation were investigated. A high magnetic field (11.5 tesla) Fourier transform ion cyclotron resonance (FTICR) mass spectrometer was coupled on-line with this high-efficiency multiple-capillary LC system through an electrospray ionization source. The capillary LC provided a peak capacity of {approx}600, and the 2-D capillary LC-FTICR provided a combined resolving power of > 6 x 10 7 polypeptide isotopic distributions. For yeast cellular tryptic digests, > 100,000 polypeptides were typically detected, and {approx}1,000 proteins can be characterized in a single run.

  3. The comparison of naturally weathered oil and artificially photo-degraded oil at the molecular level by a combination of SARA fractionation and FT-ICR MS

    International Nuclear Information System (INIS)

    Highlights: • Weathered oils from the Hebei Spirit oil spill and photo degraded oils are compared. • We investigate changes of polar species at the molecular level by 15T FT-ICR MS. • Significant reduction of sulfur class compounds in saturates fraction is observed. • The relative abundance of protonated compounds (presumably basic nitrogen compounds) increase after degradation. • Changes of polar compounds occurred by natural and photo degradation are similar. -- Abstract: Two sets of oil samples, one obtained from different weathering stages of the M/V Hebei Spirit oil spill site and the other prepared by an in vitro photo-degradation experiment, were analyzed and compared at the molecular level by atmospheric pressure photo-ionization coupled with Fourier transform ion cyclotron resonance mass spectrometry (FT-ICR MS). For a more detailed comparison at the molecular level, the oil samples were separated into saturate, aromatic, resin, and asphaltene (SARA) fractions before MS analysis. Gravimetric analysis of the SARA fractions revealed a decreased weight percentage of the aromatic fraction and an increased resin fraction in both sets of samples. Molecular-level investigations of the SARA fractions showed a significant reduction in the S1 class in the saturate fraction and increase of S1O1 class compounds with high DBE values in resin fraction. Levels of N1 and N1O1 class compounds resulting in protonated ions (presumably basic nitrogen compounds) increased after degradation compared to compounds generating molecular ions (presumably non-basic nitrogen compounds). This study revealed changes occurring in heteroatom polar species of crude oils such as sulfur and nitrogen containing compounds that have not been easily detected with conventional GC based techniques

  4. Mass measurements on neutron-deficient nuclides at SHIPTRAP and commissioning of a cryogenic narrow-band FT-ICR mass spectrometer

    Energy Technology Data Exchange (ETDEWEB)

    Ferrer Garcia, R.

    2007-07-01

    The dissertation presented here deals with high-precision Penning trap mass spectrometry on short-lived radionuclides. Owed to the ability of revealing all nucleonic interactions, mass measurements far off the line of {beta}-stability are expected to bring new insight to the current knowledge of nuclear properties and serve to test the predictive power of mass models and formulas. In nuclear astrophysics, atomic masses are fundamental parameters for the understanding of the synthesis of nuclei in the stellar environments. This thesis presents ten mass values of radionuclides around A=90 interspersed in the predicted rp-process pathway. Six of them have been experimentally determined for the first time. The measurements have been carried out at the Penning-trap mass spectrometer SHIPTRAP using the destructive time-of-flight ion-cyclotron-resonance (TOF-ICR) detection technique. Given the limited performance of the TOF-ICR detection when trying to investigate heavy/superheavy species with small production cross sections ({sigma} <1 {mu}b), a new detection system is found to be necessary. Thus, the second part of this thesis deals with the commissioning of a cryogenic double-Penning trap system for the application of a highly-sensitive, narrow-band Fourier-transform ion-cyclotron-resonance (FT-ICR) detection technique. With the non-destructive FT-ICR detection method a single singly-charged trapped ion will provide the required information to determine its mass. First off-line tests of a new detector system based on a channeltron with an attached conversion dynode, of a cryogenic pumping barrier, to guarantee ultra-high vacuum conditions during mass determination, and of the detection electronics for the required single-ion sensitivity are reported. (orig.)

  5. Mass measurements on neutron-deficient nuclides at SHIPTRAP and commissioning of a cryogenic narrow-band FT-ICR mass spectrometer

    International Nuclear Information System (INIS)

    The dissertation presented here deals with high-precision Penning trap mass spectrometry on short-lived radionuclides. Owed to the ability of revealing all nucleonic interactions, mass measurements far off the line of β-stability are expected to bring new insight to the current knowledge of nuclear properties and serve to test the predictive power of mass models and formulas. In nuclear astrophysics, atomic masses are fundamental parameters for the understanding of the synthesis of nuclei in the stellar environments. This thesis presents ten mass values of radionuclides around A=90 interspersed in the predicted rp-process pathway. Six of them have been experimentally determined for the first time. The measurements have been carried out at the Penning-trap mass spectrometer SHIPTRAP using the destructive time-of-flight ion-cyclotron-resonance (TOF-ICR) detection technique. Given the limited performance of the TOF-ICR detection when trying to investigate heavy/superheavy species with small production cross sections (σ <1 μb), a new detection system is found to be necessary. Thus, the second part of this thesis deals with the commissioning of a cryogenic double-Penning trap system for the application of a highly-sensitive, narrow-band Fourier-transform ion-cyclotron-resonance (FT-ICR) detection technique. With the non-destructive FT-ICR detection method a single singly-charged trapped ion will provide the required information to determine its mass. First off-line tests of a new detector system based on a channeltron with an attached conversion dynode, of a cryogenic pumping barrier, to guarantee ultra-high vacuum conditions during mass determination, and of the detection electronics for the required single-ion sensitivity are reported. (orig.)

  6. Recent advances in fullerene science (Invited)

    Energy Technology Data Exchange (ETDEWEB)

    Dunk, P. W.; Marshall, A. G. [Department of Chemistry and Biochemistry, 95 Chieftain Way, Florida State University, Tallahassee, Florida 32306, USA and Ion Cyclotron Resonance Program, National High Magnetic Field Laboratory, Florida State University, 1800 East Paul Dirac Drive (United States); Mulet-Gas, M.; Rodriguez-Fortea, A.; Poblet, J. M. [Departament de Química Físicai Inorgànica, Universitat Rovirai Virgili c/Marcellí Domingo s/n, 43007 Tarragona (Spain); Kroto, H. W. [Department of Chemistry and Biochemistry, 95 Chieftain Way, Florida State University, Tallahassee, Florida 32306 (United States)

    2014-12-09

    The development of very high resolution FT-ICR mass spectrometers (Marshall et al, 1998) has made a wide range of new measurements possible and by combining this new technology with laser vaporization supersonic beam methods of producing carbon species (chains, rings and fullerenes), new advances in understanding of the fullerene creation mechanisms and their reactivity have been possible. In this overview, new understanding has been developed with regard to: a) closed-network growth of fullerenes (Dunk et al, 2012a); b) small endohedral species such as MαC{sub 28} (Dunk et al., 2012b); c) metallofullerene and fullerene formation under conditions in stellar outflows with relevance to stardust (Dunk et al., 2013a) and d) The formation of heterofullerenes by direct exposure of C{sub 60} toboron vapor (Dunk et al., 2013b)

  7. High-field NMR spectroscopy and FTICR mass spectrometry: powerful discovery tools for the molecular level characterization of marine dissolved organic matter

    Directory of Open Access Journals (Sweden)

    N. Hertkorn

    2013-03-01

    exceptional resolution and depicted resolved molecular signatures in excess of a certain minimum abundance. Classical methyl groups terminating aliphatic chains represented ~15% of total methyl in all samples investigated. A noticeable fraction of methyl (~2% was bound to olefinic carbon. Methyl ethers were abundant in surface marine SPE-DOM, and the chemical diversity of carbohydrates was larger than that of freshwater and soil DOM. In all samples, we identified sp2-hybridized carbon chemical environments with discrimination of isolated and conjugated olefins and α,β-unsaturated double bonds. Olefinic proton and carbon atoms were more abundant than aromatic ones; olefinic unsaturation in marine SPE-DOM will be more directly traceable to ultimate biogenic precursors than aromatic unsaturation. The abundance of furan, pyrrol and thiophene derivatives was marginal, whereas benzene derivatives, phenols and six-membered nitrogen heterocycles were prominent; a yet unassigned set of six-membered N-heterocycles with likely more than one single nitrogen occurred in all samples. Various key polycyclic aromatic hydrocarbon substructures suggested the presence of thermogenic organic matter at all water depths. Progressive NMR cross-peak attenuation from surface to deep marine SPE-DOM was particularly strong in COSY NMR spectra and indicated a continual disappearance of biosignatures as well as entropy gain from an ever increased molecular diversity. Nevertheless, a specific near-seafloor SPE-DOM signature of unsaturated molecules recognized in both NMR and Fourier transform ion cyclotron mass spectrometry (FTICR/MS possibly originated from sediment leaching. The conformity of key NMR and FTICR/MS signatures suggested the presence of a large set of identical molecules throughout the entire ocean column even though the investigated water masses belonged to different oceanic regimes and currents. FTICR/MS showed abundant CHO, CHNO, CHOS and CHNOS molecular series with slightly increasing

  8. Analysis of impact of temperature and saltwater on Nannochloropsis salina bio-oil production by ultra high resolution APCI FT-ICR MS

    KAUST Repository

    Sanguineti, Michael Mario

    2015-05-01

    Concentrated Nannochloropsis salina paste was reconstituted in distilled water and synthetic saltwater and processed at 250°C and 300°C via hydrothermal liquefaction. The resulting bio-oils yielded a diverse distribution of product classes, as analyzed by ultra high resolution APCI FT-ICR MS. The organic fractions were analyzed and both higher temperatures and distilled water significantly increase the number of total compounds present and the number of product classes. Major bio-oil products consisted of N1O1, hydrocarbon, and O2 classes, while O1, O4, S1, N1O2, and N2O2 classes represented the more significant minor classes. Both chlorine and sulfur containing compounds were detected in both distilled and saltwater reactions, while fewer numbers of chlorine and sulfur containing products were present in the organic fraction of the saltwater reactions. Further refinement to remove the chlorine and sulfur contents appears necessary with marine microalgal bio-oils produced via hydrothermal liquefaction. The higher heating value (MJ/kg) as calculated by the Boie equation of classes of interest in the bio-oil reveals a significant potential of algal hydrothermal liquefaction products as a sustainable and renewable fuel feedstock. © 2015.

  9. Analysis and Characterization of Dissolved Organic Matter in Ice Cores as Indicators of Past Environmental Conditions Using High Resolution FTICR-MS

    Science.gov (United States)

    Boschi, V.; Grannas, A. M.; Willoughby, A. S.; Catanzano, V.; Hatcher, P.

    2015-12-01

    With rapid changes in global temperatures, research aimed at better understanding past climatic events in order to predict future trends is an area of growing importance. Carbonaceous gases stored in ice cores are known to correlate with temperature change and provide evidence of such events. However, more complex forms of carbon preserved in ice cores such as dissolved organic matter (DOM) can provide additional information relating to changes in environmental conditions over time. The examination of ice core samples presents unique challenges including detection of ultra-low concentrations of organic material and extremely limited sample amounts. In this study, solid phase extraction techniques combined with ultra-high resolution electrospray ionization Fourier transform ion cyclotron resonance mass spectrometry (ESI FTICR-MS) were utilized to successfully extract, concentrate and analyze the low concentrations of DOM in only 100 mL of ice core samples originating from various regions of Antarctica and Greenland. We characterize the DOM composition in each sample by evaluating elemental ratios, molecular formula distribution (CHO, CHON, CHOS and CHNOS) and compound class composition (lignin, tannin, lipid, condensed aromatic, protein and unsaturated hydrocarbon content). Upon characterization, we identified molecular trends in ice core DOM chemistry that correlated with past climatic events in addition to observing possible photochemical and microbial influences affecting DOM chemistry. Considering these samples range in age from 350-1175 years old, thus being formed during the Medieval Warm Period and Little Ice Age, we observed that DOM properties reflected anticipated changes in composition as influenced by warming and cooling events occurring during that time period.

  10. Changes of Petroleum Acid Distribution Characterized by FT-ICR MS in Heavy Acidic Crude Oil after True Boiling Point Distillation

    Institute of Scientific and Technical Information of China (English)

    Liu Yingrong; Zhang Qundan; Wang Wei; Liu Zelong; Zhu Xinyi; Tian Songbai

    2014-01-01

    The molecular transformations of carboxylic acids in heavy acidic SL crude before and after true boiling point distillation were examined by ultra-high resolution negative-ion electrospray ionization (ESI) Fourier transform ion cyclo-tron resonance mass spectrometry (FT-ICR MS). The acid class (heteroatom number), type (z numbers) and carbon number distributions were positively characterized. It was found out that the total acid number (TAN) of SL crude decreased after true boiling point distillation, and the abundance of O2 class in mass spectra was also found to be reduced from 67.6%to 34.5%in SL TBP mixed crude as measured by MS spectra, indicating to a potential carboxylic acid decomposition. However, it was interesting that the carboxylic acids type distribution in both oils was almost the same although their relative abundance in SL TBP mixed crude turned to be much lower, suggesting that various petroleum carboxylic acid types have the similar thermal decomposition reaction behavior. Furthermore, for each O2 type of acids in SL TBP mixed crude, the abundance of carboxylic acids with carbon number higher than 35 was reduced greatly, especially for those with carbon number higher than 60, the mass peaks of which were nearly totally removed, indicating that the large carboxylic acid molecules in heavy fractions decomposed more signiifcantly because of longer heating time during the true boiling point distillation process. As a result, the reduction of TAN may be caused by the thermal decomposition of carboxylic acids especially those with high carbon number, suggesting that quick distillation or much lower pressure is required to avoid the thermal decomposition.

  11. High field NMR spectroscopy and FTICR mass spectrometry: powerful discovery tools for the molecular level characterization of marine dissolved organic matter from the South Atlantic Ocean

    Science.gov (United States)

    Hertkorn, N.; Harir, M.; Koch, B. P.; Michalke, B.; Grill, P.; Schmitt-Kopplin, P.

    2012-01-01

    methyl (CH3) in marine DOM were nicely discriminated in DEPT HSQC NMR spectra. Classical methyl groups terminating aliphatic chains represented only ~15% of total methyl in all marine DOM investigated. Chemical shift anisotropy from carbonyl derivatives (i.e. most likely carboxylic acids) displaced aliphatic methyl 1H NMR resonances up to δH ~1.6 ppm, indicative of alicyclic geometry which furnishes more numerous short range connectivities for any given atom pairs. A noticeable fraction of methyl (~2%) was bound to olefinic carbon. The comparatively large abundance of methyl ethers in surface marine DOM contrasted with DOM of freshwater and soil origin. The chemical diversity of carbohydrates as indicated by H2CO-groups (δC ~ 62 ± 2 ppm) and anomerics (δC ~ 102 ± 7 ppm) exceeded that of freshwater and soil DOM considerably. HSQC NMR spectra were best suited to identify chemical environments of methin carbon (CH) and enabled discrimination of olefinic and aromatic cross peaks (δC > 110 ppm) and those of doubly oxygenated carbon (δC 8 ppm). Specifically, a rather confined HSQC cross peak at δH/δC = 8.2/164 ppm indicated a limited set of nitrogen heterocycles with several nitrogen atoms in analogy to RNA derivatives present in all four marine DOM. Appreciable amounts of extended HSQC and TOCSY cross peaks derived from various key polycyclic aromatic hydrocarbon substructures suggested the presence of previously proposed but NMR invisible thermogenic organic matter (TMOC) in marine DOM at all water depths. Eventually, olefinic unsaturation in marine DOM will be more directly traceable to ultimate biogenic precursors than aromatic unsaturation of which a substantial fraction originates from an aged material which from the beginning was subjected to complex and less specific biogeochemical reactions like thermal decomposition. The variance in molecular mass as indicated from Fourier transform ion cyclotron resonance (FTICR) mass spectra was limited and could not

  12. 焦化蜡油中碱性氮化合物的ESI FT-ICR MS表征及其催化裂化反应特性%CHARACTERIZATION OF BASIC NITROGEN COMPOUNDS IN COKER GAS OIL BY ESI FT-ICR MS AND THEIR CATALYTIC CRACKING PERFORMANCE

    Institute of Scientific and Technical Information of China (English)

    陈小博; 沈本贤; 孙金鹏; 山红红

    2013-01-01

    利用盐酸-乙醇溶液对焦化蜡油(CGO)中的碱性氮化合物进行了萃取分离,采用电喷雾-傅里叶变换离子回旋共振质谱仪(ESI FT-ICR MS)对CGO及其盐酸抽提物中的碱性氮化合物进行了表征,并在小型提升管催化裂化实验装置上,考察了碱性氮化合物的催化裂化反应特性.结果表明:CGO中的碱性氮化合物以N1类化合物为主,主要是带烷基或环烷基侧链的喹啉类和苯并喹啉类衍生物;在催化裂化条件下,萃取出的碱性氮化合物仍具有一定的催化裂化性能,但转化率较低,主要发生烷基侧链、环烷基侧链以及联苯桥键的断裂反应,较高含量的碱性氮化合物和多环芳烃是导致其转化率低、产物分布差的关键因素.%The basic nitrogen compounds were extracted by hydrochloric acid and alcohol from CGO.Then the types and structures of basic nitrogen species in CGO and its hydrochloric extract were characterized by Electrospray Ionization (ESI) Fourier Transform Ion Cyclotron Resonance Mass Spectrometry (FT-ICR MS),and the catalytic cracking performance of the basic nitrogen compounds was studied.The data indicate that N1 type basic nitrogen compounds are dominant in CGO and these species are mainly derivatives of quinoline and benzoquinoline with alkyl and cycloalkyl chains.Under the conditions of FCC,the basic nitrogen compounds extracted from CGO still have certain catalytic cracking ability;however,the conversion is relatively low.The bond-breakages of alkyl side-chains,cycloalkyl side-chains and biphenyl bridge are the main reaction.High content of basic nitrogen compounds and polycyclic aromatic hydrocarbons are the key factors that lead to lower conversion and poorer products distribution.

  13. High field NMR spectroscopy and FTICR mass spectrometry: powerful discovery tools for the molecular level characterization of marine dissolved organic matter from the South Atlantic Ocean

    Directory of Open Access Journals (Sweden)

    N. Hertkorn

    2012-01-01

    thiophene derivatives even if very unlikely from given elemental C/N and C/S ratios and upfield proton NMR chemical shift (δH < 6.5 ppm could not yet been ruled out entirely. In addition to classical aromatic DOM, like benzene derivatives and phenols, six-membered nitrogen heterocycles were found prominent contributors to the downfield region of proton chemical shift (δH > 8 ppm. Specifically, a rather confined HSQC cross peak at δHC = 8.2/164 ppm indicated a limited set of nitrogen heterocycles with several nitrogen atoms in analogy to RNA derivatives present in all four marine DOM. Appreciable amounts of extended HSQC and TOCSY cross peaks derived from various key polycyclic aromatic hydrocarbon substructures suggested the presence of previously proposed but NMR invisible thermogenic organic matter (TMOC in marine DOM at all water depths. Eventually, olefinic unsaturation in marine DOM will be more directly traceable to ultimate biogenic precursors than aromatic unsaturation of which a substantial fraction originates from an aged material which from the beginning was subjected to complex and less specific biogeochemical reactions like thermal decomposition.

    The variance in molecular mass as indicated from Fourier transform ion cyclotron resonance (FTICR mass spectra was limited and could not satisfactorily explain the observed disparity in NMR transverse relaxation of the four marine DOM samples. Likewise, the presence of metal ions in isolated marine DOM remained near constant or declined from surface to depth for important paramagnetic ions like Mn, Cr, Fe, Co, Ni and Cu. Iron in particular, a strong complexing paramagnetic ion, was found most abundant by a considerable margin in surface (FISH marine DOM for which well resolved COSY cross peaks were observed. Hence, facile relationships between metal content of isolated DOM (which does not reflect authentic marine DOM metal content and transverse NMR relaxation

  14. A software application for comparing large numbers of high resolution MALDI-FTICR MS spectra demonstrated by searching candidate biomarkers for glioma blood vessel formation

    Directory of Open Access Journals (Sweden)

    Smitt Peter

    2008-03-01

    Full Text Available Abstract Background A Java™ application is presented, which compares large numbers (n > 100 of raw FTICR mass spectra from patients and controls. Two peptide profile matrices can be produced simultaneously, one with occurrences of peptide masses in samples and another with the intensity of common peak masses in all the measured samples, using the peak- and background intensities of the raw data. In latter way, more significantly differentially expressed peptides are found between groups than just using the presence or absence in samples of common peak masses. The software application is tested by searching angiogenesis related proteins in glioma by comparing laser capture micro dissected- and enzymatic by trypsin digested tissue sections. Results By hierarchical clustering of the presence-absence matrix, it appears that proteins, such as hemoglobin alpha and delta subunit, fibrinogen beta and gamma chain precursor, tubulin specific chaperone A, epidermal fatty acid binding protein, neutrophil gelatinase-associated lipocalin precursor, peptidyl tRNA hydrolase 2 mitochondrial precursor, placenta specific growth hormone, and zinc finger CCHC domain containing protein 13 are significantly different expressed in glioma vessels. The up-regulated proteins in the glioma vessels with respect to the normal vessels determined by the Wilcoxon-Mann-Whitney test on the intensity matrix are vimentin, glial fibrillary acidic protein, serum albumin precursor, annexin A5, alpha cardiac and beta actin, type I cytoskeletal 10 keratin, calcium binding protein p22, and desmin. Peptide masses of calcium binding protein p22, Cdc42 effector protein 3, fibronectin precursor, and myosin-9 are exclusively present in glioma vessels. Some peptide fragments of non-muscular myosin-9 at the C-terminus are strongly up-regulated in the glioma vessels with respect to the normal vessels. Conclusion The less rigorous than in general used commercial propriety software de

  15. Advanced Ceramics

    International Nuclear Information System (INIS)

    The First Florida-Brazil Seminar on Materials and the Second State Meeting about new materials in Rio de Janeiro State show the specific technical contribution in advanced ceramic sector. The others main topics discussed for the development of the country are the advanced ceramic programs the market, the national technic-scientific capacitation, the advanced ceramic patents, etc. (C.G.C.)

  16. ADVANCE PAYMENTS

    CERN Multimedia

    Human Resources Division

    2002-01-01

    Administrative Circular Nº 8 makes provision for the granting of advance payments, repayable in several monthly instalments, by the Organization to the members of its personnel. Members of the personnel are reminded that these advances are only authorized in exceptional circumstances and at the discretion of the Director-General. In view of the current financial situation of the Organization, and in particular the loans it will have to incur, the Directorate has decided to restrict the granting of such advances to exceptional or unforeseen circumstances entailing heavy expenditure and more specifically those pertaining to social issues. Human Resources Division Tel. 73962

  17. Advance payments

    CERN Multimedia

    Human Resources Division

    2003-01-01

    Administrative Circular N 8 makes provision for the granting of advance payments, repayable in several monthly instalments, by the Organization to the members of its personnel. Members of the personnel are reminded that these advances are only authorized in exceptional circumstances and at the discretion of the Director-General. In view of the current financial situation of the Organization, and in particular the loans it will have to incur, the Directorate has decided to restrict the granting of such advances to exceptional or unforeseen circumstances entailing heavy expenditure and more specifically those pertaining to social issues. Human Resources Division Tel. 73962

  18. Advanced Microsensors

    Science.gov (United States)

    1991-01-01

    This video looks at a spinoff application of the technology from advanced microsensors -- those that monitor and determine conditions of spacecraft like the Space Shuttle. The application featured is concerned with the monitoring of the health of premature babies.

  19. Absorption Mode FTICR Mass Spectrometry Imaging

    NARCIS (Netherlands)

    Smith, D.F.; Kilgour, D.P.A.; Konijnenburg, M.; O'Connor, P.B.; Heeren, R.M.A.

    2013-01-01

    Fourier transform ion cyclotron resonance mass spectrometry offers the highest mass resolving power for molecular imaging experiments. This high mass resolving power ensures that closely spaced peaks at the same nominal mass are resolved for proper image generation. Typically higher magnetic fields

  20. Advanced nanoelectronics

    CERN Document Server

    Ismail, Razali

    2012-01-01

    While theories based on classical physics have been very successful in helping experimentalists design microelectronic devices, new approaches based on quantum mechanics are required to accurately model nanoscale transistors and to predict their characteristics even before they are fabricated. Advanced Nanoelectronics provides research information on advanced nanoelectronics concepts, with a focus on modeling and simulation. Featuring contributions by researchers actively engaged in nanoelectronics research, it develops and applies analytical formulations to investigate nanoscale devices. The

  1. AdvancED Flex 4

    CERN Document Server

    Tiwari, Shashank; Schulze, Charlie

    2010-01-01

    AdvancED Flex 4 makes advanced Flex 4 concepts and techniques easy. Ajax, RIA, Web 2.0, mashups, mobile applications, the most sophisticated web tools, and the coolest interactive web applications are all covered with practical, visually oriented recipes. * Completely updated for the new tools in Flex 4* Demonstrates how to use Flex 4 to create robust and scalable enterprise-grade Rich Internet Applications.* Teaches you to build high-performance web applications with interactivity that really engages your users.* What you'll learn Practiced beginners and intermediate users of Flex, especially

  2. Advanced calculus

    CERN Document Server

    Nickerson, HK; Steenrod, NE

    2011-01-01

    ""This book is a radical departure from all previous concepts of advanced calculus,"" declared the Bulletin of the American Mathematics Society, ""and the nature of this departure merits serious study of the book by everyone interested in undergraduate education in mathematics."" Classroom-tested in a Princeton University honors course, it offers students a unified introduction to advanced calculus. Starting with an abstract treatment of vector spaces and linear transforms, the authors introduce a single basic derivative in an invariant form. All other derivatives - gradient, divergent, curl,

  3. Advanced ferroelectricity

    CERN Document Server

    Blinc, R

    2011-01-01

    Advances in the field of ferroelectricity have implications both for basic physics and for technological applications such as memory devices, spintronic applications and electro-optic devices, as well as in acoustics, robotics, telecommunications and medicine. This book provides an account of recent developments in the field.

  4. Advanced Virgo

    CERN Multimedia

    Virgo, a first-generation interferometric gravitational wave (GW) detector, located in the European Gravitational Observatory, EGO, Cascina (Pisa-Italy) and constructed by the collaboration of French and Italian institutes (CNRS and INFN) has successfully completed its long-duration data taking runs. It is now undergoing a fundamental upgrade that exploits available cutting edges technology to open an exciting new window on the universe, with the first detection of a gravitational wave signal. Advanced Virgo (AdV) is the project to upgrade the Virgo detector to a second-generation instrument. AdV will be able to scan a volume of the Universe 1000 times larger than initial Virgo. AdV will be hosted in the same infrastructures as Virgo. The Advanced VIRGO project is funded and at present carried on by a larger collaboration of institutes belonging to CNRS- France , RMKI - Hungary, INFN- Italy, Nikhef - The Netherlands Polish Academy of Science - Poland.

  5. Advanced Nanoemulsions

    Science.gov (United States)

    Fryd, Michael M.; Mason, Thomas G.

    2012-05-01

    Recent advances in the growing field of nanoemulsions are opening up new applications in many areas such as pharmaceuticals, foods, and cosmetics. Moreover, highly controlled nanoemulsions can also serve as excellent model systems for investigating basic scientific questions about soft matter. Here, we highlight some of the most recent developments in nanoemulsions, focusing on methods of formation, surface modification, material properties, and characterization. These developments provide insight into the substantial advantages that nanoemulsions can offer over their microscale emulsion counterparts.

  6. Advanced LIGO

    OpenAIRE

    Aasi, J.; Abbott, B.; Abbott, R.; Abbott, T.; Abernathy, M; Ackley, K.; Adams, C.; Adams, T.; Addesso, P.; Adhikari, R.; Adya, V.; Affeldt, C.; Aggarwal, N.; Aguiar, O.; Ain, A.

    2014-01-01

    The Advanced LIGO gravitational wave detectors are second-generation instruments designed and built for the two LIGO observatories in Hanford, WA and Livingston, LA, USA. The two instruments are identical in design, and are specialized versions of a Michelson interferometer with 4 km long arms. As in Initial LIGO, Fabry–Perot cavities are used in the arms to increase the interaction time with a gravitational wave, and power recycling is used to increase the effective laser power. Signal recyc...

  7. Advanced Combustion

    Energy Technology Data Exchange (ETDEWEB)

    Holcomb, Gordon R. [NETL

    2013-03-11

    The activity reported in this presentation is to provide the mechanical and physical property information needed to allow rational design, development and/or choice of alloys, manufacturing approaches, and environmental exposure and component life models to enable oxy-fuel combustion boilers to operate at Ultra-Supercritical (up to 650{degrees}C & between 22-30 MPa) and/or Advanced Ultra-Supercritical conditions (760{degrees}C & 35 MPa).

  8. Advanced DVI+

    Energy Technology Data Exchange (ETDEWEB)

    Kwon, Tae Soon; Lee, S. T.; Euh, D. J.; Chu, I. C.; Youn, Y. J. [Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of)

    2012-10-15

    A new advanced safety feature of DVI+ (Direct Vessel Injection Plus) for the APR+ (Advanced Power Reactor Plus), to mitigate the ECC (Emergency Core Cooling) bypass fraction and to prevent switching an ECC outlet to a break flow inlet during a DVI line break, is presented for an advanced DVI system. In the current DVI system, the ECC water injected into the downcomer is easily shifted to the broken cold leg by a high steam cross flow which comes from the intact cold legs during the late reflood phase of a LBLOCA (Large Break Loss Of Coolant Accident). For the new DVI+ system, an ECBD (Emergency Core Barrel Duct) is installed on the outside of a core barrel cylinder. The ECBD has a gap (From the core barrel wall to the ECBD inner wall to the radial direction) of 3/25-7/25 of the downcomer annulus gap. The DVI nozzle and the ECBD are only connected by the ECC water jet, which is called a hydrodynamic water bridge, during the ECC injection period. Otherwise these two components are disconnected from each other without any pipes inside the downcomer. The ECBD is an ECC downward isolation flow sub-channel which protects the ECC water from the high speed steam crossflow in the downcomer annulus during a LOCA event. The injected ECC water flows downward into the lower downcomer through the ECBD without a strong entrainment to a steam cross flow. The outer downcomer annulus of the ECBD is the major steam flow zone coming from the intact cold leg during a LBLOCA. During a DVI line break, the separated DVI nozzle and ECBD have the effect of preventing the level of the cooling water from being lowered in the downcomer due to an inlet-outlet reverse phenomenon at the lowest position of the outlet of the ECBD.

  9. Advanced mathematics

    CERN Document Server

    Gupta, CB; Kumar, V

    2009-01-01

    About the Book: This book `Advanced Mathematics` is primarily designed for B.Tech., IV Semester (EE and EC branch) students of Rajasthan Technical University. The subject matter is discussed in a lucid manner. The discussion is covered in five units: Unit I: deals with Numerical Analysis, Unit-II: gives different aspects of Numerical Analysis, Unit-III: Special Function, Unit-IV:Statistics and Probability, Calculus of Variation and Transforms are discussed in Unit V. All the theoretical concepts are explained through solved examples. Besides, a large number of unsolved problems on each top

  10. Advanced calculus

    CERN Document Server

    Friedman, Avner

    2007-01-01

    This rigorous two-part treatment advances from functions of one variable to those of several variables. Intended for students who have already completed a one-year course in elementary calculus, it defers the introduction of functions of several variables for as long as possible, and adds clarity and simplicity by avoiding a mixture of heuristic and rigorous arguments.The first part explores functions of one variable, including numbers and sequences, continuous functions, differentiable functions, integration, and sequences and series of functions. The second part examines functions of several

  11. Advanced LIGO

    CERN Document Server

    ,

    2014-01-01

    The Advanced LIGO gravitational wave detectors are second generation instruments designed and built for the two LIGO observatories in Hanford, WA and Livingston, LA. The two instruments are identical in design, and are specialized versions of a Michelson interferometer with 4 km long arms. As in initial LIGO, Fabry-Perot cavities are used in the arms to increase the interaction time with a gravitational wave, and power recycling is used to increase the effective laser power. Signal recycling has been added in Advanced LIGO to improve the frequency response. In the most sensitive frequency region around 100 Hz, the design strain sensitivity is a factor of 10 better than initial LIGO. In addition, the low frequency end of the sensitivity band is moved from 40 Hz down to 10 Hz. All interferometer components have been replaced with improved technologies to achieve this sensitivity gain. Much better seismic isolation and test mass suspensions are responsible for the gains at lower frequencies. Higher laser power, ...

  12. Future advances.

    Science.gov (United States)

    Celesia, Gastone G; Hickok, Gregory

    2015-01-01

    Future advances in the auditory systems are difficult to predict, and only educated guesses are possible. It is expected that innovative technologies in the field of neuroscience will be applied to the auditory system. Optogenetics, Brainbow, and CLARITY will improve our knowledge of the working of neural auditory networks and the relationship between sound and language, providing a dynamic picture of the brain in action. CLARITY makes brain tissue transparent and offers a three-dimensional view of neural networks, which, combined with genetically labeling neurons with multiple, distinct colors (Optogenetics), will provide detailed information of the complex brain system. Molecular functional magnetic resonance imaging (MRI) will allow the study of neurotransmitters detectable by MRI and their function in the auditory pathways. The Human Connectome project will study the patterns of distributed brain activity that underlie virtually all aspects of cognition and behavior and determine if abnormalities in the distributed patterns of activity may result in hearing and behavior disorders. Similarly, the programs of Big Brain and ENIGMA will improve our understanding of auditory disorders. New stem-cell therapy and gene therapies therapy may bring about a partial restoration of hearing for impaired patients by inducing regeneration of cochlear hair cells. PMID:25726297

  13. Advances in chemical physics

    CERN Document Server

    Prigogine, Ilya

    2009-01-01

    The Advances in Chemical Physics series provides the chemical physics and physical chemistry fields with a forum for critical, authoritative evaluations of advances in every area of the discipline. Filled with cutting-edge research reported in a cohesive manner not found elsewhere in the literature, each volume of the Advances in Chemical Physics series serves as the perfect supplement to any advanced graduate class devoted to the study of chemical physics.

  14. ACR-700 advanced technologies

    International Nuclear Information System (INIS)

    A successful advanced reactor plant will have optimized economics including reduced operating and maintenance costs, improved performance, and enhanced safety. Incorporating improvements based on advanced technologies ensures cost, safety and operational competitiveness of the ACR-700. These advanced technologies include modern configuration management; construction technologies; operational technology for the control centre and information systems for plant monitoring and analysis. This paper summarizes the advanced technologies used to achieve construction and operational improvements to enhance plant economic competitiveness, advances in the operational technology used for reactor control, and presents the development of the Smart CANDU suite of tools and its application to existing operating reactors and to the ACR-700. (author)

  15. Advances in chemical physics

    CERN Document Server

    Rice, Stuart A

    2012-01-01

    The Advances in Chemical Physics series-the cutting edge of research in chemical physics The Advances in Chemical Physics series provides the chemical physics field with a forum for critical, authoritative evaluations of advances in every area of the discipline. Filled with cutting-edge research reported in a cohesive manner not found elsewhere in the literature, each volume of the Advances in Chemical Physics series serves as the perfect supplement to any advanced graduate class devoted to the study of chemical physics. This volume explores: Quantum Dynamical Resonances in Ch

  16. Advances in chemical physics

    CERN Document Server

    Rice, Stuart A

    2012-01-01

    The Advances in Chemical Physics series-the cutting edge of research in chemical physics The Advances in Chemical Physics series provides the chemical physics and physical chemistry fields with a forum for critical, authoritative evaluations of advances in every area of the discipline. Filled with cutting-edge research reported in a cohesive manner not found elsewhere in the literature, each volume of the Advances in Chemical Physics series presents contributions from internationally renowned chemists and serves as the perfect supplement to any advanced graduate class devoted to the study o

  17. Advanced information society (12)

    Science.gov (United States)

    Komatsuzaki, Seisuke

    In this paper, the original Japanese idea of "advanced information society" was reviewed at the first step. Thus, advancement of information/communication technology, advancement of information/communication needs and tendency of industrialization of information" were examined. Next, by comparing studies on advanced information society in various countries, the Japanese characteristics of consensus building was reviewed. Finally, in pursuit of prospect and tasks for the society, advancement of innovation and convergence information/communication technology, information/communication needs, institutional environment for utilization of information/communication and countermeasures against information pollution. Matching of information/communication technology and needs, besides with countermeasures against information pollution were discussed.

  18. Advances in chemical physics

    CERN Document Server

    Rice, Stuart A

    2011-01-01

    The Advances in Chemical Physics series-the cutting edge of research in chemical physics The Advances in Chemical Physics series provides the chemical physics and physical chemistry fields with a forum for critical, authoritative evaluations of advances in every area of the discipline. Filled with cutting-edge research reported in a cohesive manner not found elsewhere in the literature, each volume of the Advances in Chemical Physics series offers contributions from internationally renowned chemists and serves as the perfect supplement to any advanced graduate class devoted to the study of che

  19. Advances in chemical Physics

    CERN Document Server

    Rice, Stuart A

    2011-01-01

    The Advances in Chemical Physics series-the cutting edge of research in chemical physics The Advances in Chemical Physics series provides the chemical physics and physical chemistry fields with a forum for critical, authoritative evaluations of advances in every area of the discipline. Filled with cutting-edge research reported in a cohesive manner not found elsewhere in the literature, each volume of the Advances in Chemical Physics series offers contributions from internationally renowned chemists and serves as the perfect supplement to any advanced graduate class devoted to the study of che

  20. Advances in Applied Mechanics

    OpenAIRE

    2014-01-01

    Advances in Applied Mechanics draws together recent significant advances in various topics in applied mechanics. Published since 1948, Advances in Applied Mechanics aims to provide authoritative review articles on topics in the mechanical sciences, primarily of interest to scientists and engineers working in the various branches of mechanics, but also of interest to the many who use the results of investigations in mechanics in various application areas, such as aerospace, chemical, civil, en...

  1. Editorial: Advanced learning technologies

    OpenAIRE

    Yu-Ju Lan; Gang-Shan Fu; Stephen J.H. Yang; Jeff J.S. Huang

    2012-01-01

    Recent rapid development of advanced information technology brings high expectations of its potential to improvement and innovations in learning. This special issue is devoted to using some of the emerging technologies issues related to the topic of education and knowledge sharing, involving several cutting edge research outcomes from recent advancement of learning technologies. Advanced learning technologies are the composition of various related technologies and concepts such as mobile tech...

  2. Structural level characterization of base oils using advanced analytical techniques

    KAUST Repository

    Hourani, Nadim

    2015-05-21

    Base oils, blended for finished lubricant formulations, are classified by the American Petroleum Institute into five groups, viz., groups I-V. Groups I-III consist of petroleum based hydrocarbons whereas groups IV and V are made of synthetic polymers. In the present study, five base oil samples belonging to groups I and III were extensively characterized using high performance liquid chromatography (HPLC), comprehensive two-dimensional gas chromatography (GC×GC), and Fourier transform ion cyclotron resonance mass spectrometry (FT-ICR MS) equipped with atmospheric pressure chemical ionization (APCI) and atmospheric pressure photoionization (APPI) sources. First, the capabilities and limitations of each analytical technique were evaluated, and then the availed information was combined to reveal compositional details on the base oil samples studied. HPLC showed the overwhelming presence of saturated over aromatic compounds in all five base oils. A similar trend was further corroborated using GC×GC, which yielded semiquantitative information on the compound classes present in the samples and provided further details on the carbon number distributions within these classes. In addition to chromatography methods, FT-ICR MS supplemented the compositional information on the base oil samples by resolving the aromatics compounds into alkyl- and naphtheno-subtituted families. APCI proved more effective for the ionization of the highly saturated base oil components compared to APPI. Furthermore, for the detailed information on hydrocarbon molecules FT-ICR MS revealed the presence of saturated and aromatic sulfur species in all base oil samples. The results presented herein offer a unique perspective into the detailed molecular structure of base oils typically used to formulate lubricants. © 2015 American Chemical Society.

  3. Advances in PHWR design

    International Nuclear Information System (INIS)

    Recent advances by AECL in improved performance, cost reduction and safety improvement of CANDU reactors are described. Topics include: computer-aided design tools, up-front licensing, site utilization, plant life management, construction techniques, plant control, safety-critical software, advanced fuels, human-machine interface, heat sinks, radiation protection, feedback to design, emergency core cooling and probabilistic safety assessment

  4. Advances in chemical physics

    CERN Document Server

    Rice, Stuart A

    2008-01-01

    This series provides the chemical physics field with a forum for critical, authoritative evaluations of advances in every area of the discipline. This stand-alone special topics volume reports recent advances in electron-transfer research with significant, up-to-date chapters by internationally recognized researchers.

  5. Advanced Manufacturing Technologies

    Science.gov (United States)

    Fikes, John

    2016-01-01

    Advanced Manufacturing Technologies (AMT) is developing and maturing innovative and advanced manufacturing technologies that will enable more capable and lower-cost spacecraft, launch vehicles and infrastructure to enable exploration missions. The technologies will utilize cutting edge materials and emerging capabilities including metallic processes, additive manufacturing, composites, and digital manufacturing. The AMT project supports the National Manufacturing Initiative involving collaboration with other government agencies.

  6. Advanced uranium enrichment technologies

    International Nuclear Information System (INIS)

    The Advanced Gas Centrifuge and Atomic Vapor Laser Isotope Separation methods are described. The status and potential of the technologies are summarized, the programs outlined, and the economic incentives are noted. How the advanced technologies, once demonstrated, might be deployed so that SWV costs in the 1990s can be significantly reduced is described

  7. Advanced Aircraft Material

    Directory of Open Access Journals (Sweden)

    Vivek Kumar Prince

    2013-06-01

    Full Text Available There has been long debate on “advanced aircraft material” from past decades & researchers too came out with lots of new advanced material like composites and different aluminum alloys. Now days a new advancement that is in great talk is third generation Aluminum-lithium alloy. Newest Aluminum-lithium alloys are found out to have low density, higher elastic modulus, greater stiffness, greater cryogenic toughness, high resistance to fatigue cracking and improved corrosion resistance properties over the earlier used aircraft material as mentioned in Table 3 [1-5]. Comparison had been made with nowadays used composite material and is found out to be more superior then that

  8. Advanced materials-2007

    International Nuclear Information System (INIS)

    The 10th International Symposium on Advanced Materials (ISAM) was held from 3-7 September, 2007. From this symposium, material scientists and engineers can keep abreast with recent technologies involving advanced structural and functional materials. The proceeding of ISAM includes 94 papers which have been divided into six different sections: i) Development in material processing ii) Surface Engineering iii) phase transformation iv) advances in magnetic materials v) Nanotechnology and vi) reliability and life assessment. ISAM provides the opportunity to exchange technical know-how amongst Scientists, Engineers and researchers. (A.B.)

  9. Editorial: Advanced learning technologies

    Directory of Open Access Journals (Sweden)

    Yu-Ju Lan

    2012-03-01

    Full Text Available Recent rapid development of advanced information technology brings high expectations of its potential to improvement and innovations in learning. This special issue is devoted to using some of the emerging technologies issues related to the topic of education and knowledge sharing, involving several cutting edge research outcomes from recent advancement of learning technologies. Advanced learning technologies are the composition of various related technologies and concepts such as mobile technologies and social media towards learner centered learning. This editorial note provides an overview of relevant issues discussed in this special issue.

  10. Advanced healthcare materials

    CERN Document Server

    Tiwari, Ashutosh

    2014-01-01

    Advanced materials are attracting strong interest in the fundamental as well as applied sciences and are being extensively explored for their potential usage in a range of healthcare technological and biological applications. Advanced Healthcare Nanomaterials summarises the current status of knowledge in the fields of advanced materials for functional therapeutics, point-of-care diagnostics, translational materials, up and coming bio-engineering devices. The book highlights the key features which enable engineers to design stimuli-responsive smart nanoparticles, novel biomaterials, nan

  11. Managing Advanced Parkinson Disease

    Science.gov (United States)

    ... well.” 11 Managing Advanced Parkinson Disease DENTAL CARE Oral hygiene should remain an important part of the daily routine in order to prevent serious dental problems and the development of other illnesses. The ...

  12. [Advanced resuscitation of adults

    DEFF Research Database (Denmark)

    Lippert, F.K.; Lauritsen, T.L.; Torp-Pedersen, C.

    2008-01-01

    International and European Resuscitation Council (ERC) Guidelines for Resuscitation 2005 implicate major changes in resuscitation, including new universal treatment algorithms. This brief summary of Guidelines 2005 for advanced resuscitation of adult cardiac arrest victims is based upon the ERC...

  13. Advance Care Planning

    Science.gov (United States)

    ... put on a breathing machine. Organ and tissue donation allows organs or body parts from a generally healthy person ... to your driver’s license. Some people also include organ donation in their advance care planning documents. At the ...

  14. Advanced functional materials

    CERN Document Server

    2011-01-01

    This book reviews the results of recent research on new materials arising from progress in polymer, ceramic, sensor, and fuel cell technology, including advanced inorganic-organic-hybrid polymeric materials, high functional sensor, and microbial fuel cells.

  15. Advanced Lab Consortium ``Conspiracy''

    Science.gov (United States)

    Reichert, Jonathan F.

    2006-03-01

    Advanced Laboratory instruction is a time-honored and essential element of an undergraduate physics education. But, from my vantage point, it has been neglected by the two major professional societies, APS and AAPT. At some schools, it has been replaced by ``research experiences,'' but I contend that very few of these experiences in the research lab, particularly in the junior year, deliver what they promise. It is time to focus the attention of APS, AAPT, and the NSF on the advanced lab. We need to create an Advanced Lab Consortium (ALC) of faculty and staff to share experiments, suppliers, materials, pedagogy, ideas, in short to build a professional network for those committed to advanced lab instruction. The AAPT is currently in serious discussions on this topic and my company stands ready with both financial and personnel resources to support the effort. This talk is a plea for co-conspirators.

  16. Advance Payment ACO Model

    Data.gov (United States)

    U.S. Department of Health & Human Services — The Advance Payment Model is designed for physician-based and rural providers who have come together voluntarily to give coordinated high quality care to the...

  17. Advanced Missile Signature Center

    Data.gov (United States)

    Federal Laboratory Consortium — The Advanced Missile Signature Center (AMSC) is a national facility supporting the Missile Defense Agency (MDA) and other DoD programs and customers with analysis,...

  18. Advanced Topics in Aerodynamics

    DEFF Research Database (Denmark)

    Filippone, Antonino

    1999-01-01

    "Advanced Topics in Aerodynamics" is a comprehensive electronic guide to aerodynamics,computational fluid dynamics, aeronautics, aerospace propulsion systems, design and relatedtechnology. We report data, tables, graphics, sketches,examples, results, photos, technical andscientific literature, for...

  19. Advances in Numerical Methods

    CERN Document Server

    Mastorakis, Nikos E

    2009-01-01

    Features contributions that are focused on significant aspects of current numerical methods and computational mathematics. This book carries chapters that advanced methods and various variations on known techniques that can solve difficult scientific problems efficiently.

  20. Advanced Welding Concepts

    Science.gov (United States)

    Ding, Robert J.

    2010-01-01

    Four advanced welding techniques and their use in NASA are briefly reviewed in this poster presentation. The welding techniques reviewed are: Solid State Welding, Friction Stir Welding (FSW), Thermal Stir Welding (TSW) and Ultrasonic Stir Welding.

  1. The Advanced Energy Initiative

    Science.gov (United States)

    Milliken, JoAnn; Joseck, Fred; Wang, Michael; Yuzugullu, Elvin

    The President's Advanced Energy Initiative (AEI), launched in 2006, addresses the challenges of energy supply and demand facing our Nation by supporting research and development of advanced technologies for transportation and stationary power generation. The AEI portfolio includes clean coal, nuclear and renewable energy technologies (solar and wind) for stationary power generation and advanced battery technologies, cellulosic ethanol as a fuel and hydrogen fuel cells for transportation. These research and development programs are underpinned by comprehensive life-cycle analysis efforts using models such as Hydrogen Analysis (H2A) and Greenhouse Gases, Regulated Emissions and Energy Use in Transportation (GREET) to enable a better understanding of the characteristics and trade-offs associated with advanced energy options and to help decision makers choose viable pathways for clean, reliable and affordable energy.

  2. Advances in Higher Education

    OpenAIRE

    Doménech i De Soria, Josep; LLORET ALOS, JAIME; Vincent Vela, Maria Cinta; ZURIAGA AGUSTÍ, ELENA; Poza Plaza, Elena de la

    2016-01-01

    Higher education institutions play an important role as leaders in knowledge creation and dissemination by setting the grounds for society to advance and to improve welfare. Despite the long-standing tradition of some higher education systems, Higher Education continuously evolves to adapt to the challenges that current societies open up to. The objective of this book is to capture some recent advances made in Higher Education by addressing these challenges. To do so, some specific topics...

  3. Materials for advanced packaging

    CERN Document Server

    Lu, Daniel

    2010-01-01

    Significant progress has been made in advanced packaging in recent years. Several new packaging techniques have been developed and new packaging materials have been introduced. This book provides a comprehensive overview of the recent developments in this industry, particularly in the areas of microelectronics, optoelectronics, digital health, and bio-medical applications. The book discusses established techniques, as well as emerging technologies, in order to provide readers with the most up-to-date developments in advanced packaging.

  4. Joining of advanced materials

    CERN Document Server

    Messler, Robert W

    1993-01-01

    Provides an unusually complete and readable compilation of the primary and secondary options for joining conventional materials in non-conventional ways. Provides unique coverage of adhesive bonding using both organic and inorganic adhesives, cements and mortars. Focuses on materials issues without ignoring issues related to joint design, production processing, quality assurance, process economics, and joining performance in service.Joining of advanced materials is a unique treatment of joining of both conventional and advanced metals andalloys, intermetallics, ceramics, glasses, polymers, a

  5. Advances in Plastic Surgery

    OpenAIRE

    McDonald, Harold D.; Luis O. Vasconez

    1982-01-01

    Recent progress in plastic surgery has been rapid and many new techniques have been developed. Reconstructive procedures have been advanced by a better understanding of the anatomy of the blood supply to skin and muscle, with the subsequent development of the use of axial flaps, musculocutaneous flaps and neurosensory flaps. Burn treatment has advanced greatly, making it possible to successfully treat larger and more complicated burns. The development of microsurgery has made possible free-fl...

  6. Materials for advanced packaging

    CERN Document Server

    Wong, CP

    2008-01-01

    Significant progress has been made in advanced packaging in recent years. Several new packaging techniques have been developed and new packaging materials have been introduced. This book provides a comprehensive overview of the recent developments in this industry, particularly in the areas of microelectronics, optoelectronics, digital health, and bio-medical applications. The book discusses established techniques, as well as emerging technologies, in order to provide readers with the most up-to-date developments in advanced packaging.

  7. Advances in atomic spectroscopy

    CERN Document Server

    Sneddon, J

    1997-01-01

    This series describes selected advances in the area of atomic spectroscopy. It is primarily intended for the reader who has a background in atmoic spectroscopy; suitable to the novice and expert. Although a widely used and accepted method for metal and non-metal analysis in a variety of complex samples, Advances in Atomic Spectroscopy covers a wide range of materials. Each Chapter will completely cover an area of atomic spectroscopy where rapid development has occurred.

  8. Advanced Welding Applications

    Science.gov (United States)

    Ding, Robert J.

    2010-01-01

    Some of the applications of advanced welding techniques are shown in this poster presentation. Included are brief explanations of the use on the Ares I and Ares V launch vehicle and on the Space Shuttle Launch vehicle. Also included are microstructural views from four advanced welding techniques: Variable Polarity Plasma Arc (VPPA) weld (fusion), self-reacting friction stir welding (SR-FSW), conventional FSW, and Tube Socket Weld (TSW) on aluminum.

  9. Advances in bistatic radar

    CERN Document Server

    Willis, Nick

    2007-01-01

    Advances in Bistatic Radar updates and extends bistatic and multistatic radar developments since publication of Willis' Bistatic Radar in 1991. New and recently declassified military applications are documented. Civil applications are detailed including commercial and scientific systems. Leading radar engineers provide expertise to each of these applications. Advances in Bistatic Radar consists of two major sections: Bistatic/Multistatic Radar Systems and Bistatic Clutter and Signal Processing. Starting with a history update, the first section documents the early and now declassified military

  10. Advanced Situation Awareness Technologies Project

    Data.gov (United States)

    National Aeronautics and Space Administration — Advanced Situation Awareness Technologies (ASAT) will facilitate exploration of the moon surface, and other planetary bodies. ASAT will create an Advanced Situation...

  11. Recruit and ADVANCE

    Science.gov (United States)

    Rosser, Sue V.

    2007-04-01

    Beginning in 2001, the National Science Foundation launched the ADVANCE Initiative, which has now awarded more than 70 million to some thirty institutions for transformations to advance women. Results of studies on how to attract and retain women students and faculty underpinned our ADVANCE Institutional Transformation grant funded by the NSF for 3.7 million for five years, beginning in 2001. As co-principal investigator on this grant, I insured that this research informed the five major threads of the grant: 1) Four termed ADVANCE professors to mentor junior women faculty in each college; 2) Collection of MIT-Report-like data indicators to assess whether advancement of women really occurs during and after the institutional transformation undertaken through ADVANCE; 3) Family-friendly policies and practices to stop the tenure clock and provide active service, modified duties, lactation stations and day care; 4) Mini-retreats to facilitate access for tenure-track women faculty to male decision-makers and administrators for informal conversations and discussion on topics important to women faculty; 5) Removal of subtle gender, racial, and other biases in promotion and tenure. The dynamic changes resulting from the grant in quality of mentoring, new understanding of promotion and tenure, numbers of women retained and given endowed chairs, and emergence of new family friendly policies gave me hope for genuine diversification of leadership in science and technology. As the grant funding ends, the absence of NSF prestige and monitoring, coupled with a change in academic leadership at the top, provide new challenges for institutionalization, recruitment, and advancement of women into leadership positions in science and engineering.

  12. Advanced reactor licensing issues

    International Nuclear Information System (INIS)

    In July 1986 the US Nuclear Regulatory Commission issued a Policy Statement on the Regulation of Advanced Nuclear Power Plants. As part of this policy advanced reactor designers were encouraged to interact with NRC early in the design process to obtain feedback regarding licensing requirements for advanced reactors. Accordingly, the staff has been interacting with the Department of Energy (DOE) and its contractors on the review of three advanced reactor conceptual designs: one modular High Temperature Gas-Cooled Reactor (MHTGR) and two Liquid Metal Reactors (LMRs). As a result of these interactions certain safety issues associated with these advanced reactor designs have been identified as key to the licensability of the designs as proposed by DOE. The major issues in this regard are: (1) selection and treatment of accident scenarios; (2) selection of siting source term; (3) performance and reliability of reactor shutdown and decay heat removal systems; (4) need for conventional containment; (5) need for conventional emergency evacuation; (6) role of the operator; (7) treatment of balance of plant; and (8) modular approach. This paper provides a status of the NRC review effort, describes the above issues in more detail and provides the current status and approach to the development of licensing guidance on each

  13. Advancement & Promotion Review: 2003

    CERN Multimedia

    2003-01-01

    Advancement, exceptional advancement and promotion decisions were made at the end of June, following the procedures published in Weekly Bulletin No. 13/2003. These decisions were included, where applicable, in the salaries for the month of July 2003. The award of the periodic step was communicated to staff by the salary shown on the July salary slip. All other decisions are communicated by separate notification. The names of staff receiving exceptional advancements or promotions are now published on the HR Division website and are accessible for consultation only at the following address: http://cern.ch/hr-div/internal/personnel/advlist_2003.asp It is recalled that change of career path proposals submitted to the Technical Engineers and Administrative Careers Committee (TEACC) or to Human Resources Division are being examined with a view to preparing the latters' recommendations by the end of September 2003. Final decisions will be applied retroactively to 1 July 2003. Human Resources Division Tel:...

  14. ADVANCEMENT & PROMOTION REVIEW: 2002

    CERN Multimedia

    2002-01-01

    Advancement, exceptional advancement and promotion decisions were made at the beginning of July, under the new career structure scheme and following the procedures published in Weekly Bulletin No. 11/2002. These decisions were included, where applicable, in the salaries for the month of July 2002. The award of the periodic step was communicated to staff by the salary shown on the July salary slip. All other decisions are communicated by separate notification. The names of staff receiving exceptional advancements or promotions will be published this year on the HR Division website and are accessible for consultation only at the following address : http://cern.ch/hr-div/internal/personnel/advlist.asp It is recalled that change of career path proposals submitted to the Technical Engineers and Administrative Careers Committee (TEACC) or to Human Resources Division are being examined with a view to preparing the latters' recommendations by the end of September 2002. Final decisions will be applied retroactivel...

  15. Advanced flip chip packaging

    CERN Document Server

    Lai, Yi-Shao; Wong, CP

    2013-01-01

    Advanced Flip Chip Packaging presents past, present and future advances and trends in areas such as substrate technology, material development, and assembly processes. Flip chip packaging is now in widespread use in computing, communications, consumer and automotive electronics, and the demand for flip chip technology is continuing to grow in order to meet the need for products that offer better performance, are smaller, and are environmentally sustainable. This book also: Offers broad-ranging chapters with a focus on IC-package-system integration Provides viewpoints from leading industry executives and experts Details state-of-the-art achievements in process technologies and scientific research Presents a clear development history and touches on trends in the industry while also discussing up-to-date technology information Advanced Flip Chip Packaging is an ideal book for engineers, researchers, and graduate students interested in the field of flip chip packaging.

  16. Advances in business ICT

    CERN Document Server

    Pełech-Pilichowski, Tomasz

    2014-01-01

    Futurists and scientists alike profess the coming of a new era in the history – the knowledge era. The notion of knowledge is as old as humans’ self-consciousness, but new challenges appear. The meaning of the word “knowledge” is changing from cognitive notion to a technical term denoting a structured economic resource to be actively managed. This contributed volume is a result of vivid and extremely valuable discussions held at 3rd International Workshop on Advances in Business ICT (ABICT) in Wrocław, Poland, September 9-12, 2012. The workshop focused on Advances in Business ICT approached from a multidisciplinary perspective. It provided an international forum for scientists/experts from academia and industry to discuss and exchange current results, applications, new ideas of ongoing research and experience on all aspects of Business Intelligence. ABICT has also been an opportunity to demonstrate different ideas and tools for developing and supporting organizational creativity, as well as advances ...

  17. Advanced Worker Protection System

    International Nuclear Information System (INIS)

    The Advanced Worker Protection System (AWPS) is a liquid-air-based, self-contained breathing and cooling system with a duration of 2 hrs. AWPS employs a patented system developed by Oceaneering Space Systems (OSS), and was demonstrated at their facility in Houston, TX as well as at Kansas State University, Manhattan. The heart of the system is the life-support backpack that uses liquid air to provide cooling as well as breathing gas to the worker. The backpack is combined with advanced protective garments, an advanced liquid cooling garment (LCG), a respirator, and communications and support equipment. The prototype unit development and testing under Phase 1 has demonstrated that AWPS has the ability to meet performance criteria. These criteria were developed with an understanding of both the AWPS capabilities and the DOE decontamination and decommissioning (D and D) activities protection needs

  18. Advanced instrumentation for reprocessing.

    Energy Technology Data Exchange (ETDEWEB)

    Cipiti, Benjamin B.

    2005-10-01

    Recent interest in reprocessing nuclear fuel in the U.S. has led to advanced separations processes that employ continuous processing and multiple extraction steps. These advanced plants will need to be designed with state-of-the-art instrumentation for materials accountancy and control. This research examines the current and upcoming instrumentation for nuclear materials accountancy for those most suited to the reprocessing environment. Though this topic has received attention time and again in the past, new technologies and changing world conditions require a renewed look and this subject. The needs for the advanced UREX+ separations concept are first identified, and then a literature review of current and upcoming measuring techniques is presented. The report concludes with a preliminary list of recommended instruments and measurement locations.

  19. Advanced materials-2005

    International Nuclear Information System (INIS)

    The 9. International Symposium on Advanced Materials (ISAM) was held from 19-22 September, 2005. This popular biennial event is one of the prime international forums in South Asia where material scientists and engineers can keep abreast with recent technologies involving advanced structural and functional materials. The technical committee of ISAM received 213 papers, 49 from abroad 164 from within the country. These papers were submitted in response to five important topics; i) Processing, Production and Developments, ii) Surface Engineering, iii) Phase Transformation and Characterization, iv) Advances in Magnetic Materials and v) Reliability and Life Assessment. The proceedings of the 9. ISAM consists of 108 reviewed papers. This symposium provided an ideal opportunity for exchange of information amongst scientists, engineers, and researchers. (A.B.)

  20. Advanced Hydrogen Turbine Development

    Energy Technology Data Exchange (ETDEWEB)

    Marra, John [Siemens Energy, Inc., Orlando, FL (United States)

    2015-09-30

    Under the sponsorship of the U.S. Department of Energy (DOE) National Energy Technology Laboratories, Siemens has completed the Advanced Hydrogen Turbine Development Program to develop an advanced gas turbine for incorporation into future coal-based Integrated Gasification Combined Cycle (IGCC) plants. All the scheduled DOE Milestones were completed and significant technical progress was made in the development of new technologies and concepts. Advanced computer simulations and modeling, as well as subscale, full scale laboratory, rig and engine testing were utilized to evaluate and select concepts for further development. Program Requirements of: A 3 to 5 percentage point improvement in overall plant combined cycle efficiency when compared to the reference baseline plant; 20 to 30 percent reduction in overall plant capital cost when compared to the reference baseline plant; and NOx emissions of 2 PPM out of the stack. were all met. The program was completed on schedule and within the allotted budget

  1. The Advanced LIGO Detectors

    Science.gov (United States)

    Fritschel, Peter

    2016-03-01

    After decades of development, the Advanced LIGO gravitational wave detectors are now operating, and they completed their first observational run in early 2016. Advanced LIGO consists of two 4-km scale interferometric detectors located at separate sites in the US. The first year of detector commissioning that led to the first observation run produced instruments that have several times better sensitivity to gravitational-wave strain than previous instruments. At their final design sensitivity, the detectors will be another factor of 2-3x more sensitive than current performance. This talk will cover the design of Advanced LIGO, explain how the sensitivity improvements have been achieved, and lay out the path to reaching final design sensitivity.

  2. Advanced Magnetic Nanostructures

    CERN Document Server

    Sellmyer, David

    2006-01-01

    Advanced Magnetic Nanostructures is devoted to the fabrication, characterization, experimental investigation, theoretical understanding, and utilization of advanced magnetic nanostructures. Focus is on various types of 'bottom-up' and 'top-down' artificial nanostructures, as contrasted to naturally occurring magnetic nanostructures, such as iron-oxide inclusions in magnetic rocks, and to structures such as perfect thin films. Chapter 1 is an introduction into some basic concepts, such as the definitions of basic magnetic quantities. Chapters 2-4 are devoted to the theory of magnetic nanostructures, Chapter 5 deals with the characterization of the structures, and Chapters 6-10 are devoted to specific systems. Applications of advanced magnetic nanostructures are discussed in Chapters11-15 and, finally, the appendix lists and briefly discusses magnetic properties of typical starting materials. Industrial and academic researchers in magnetism and related areas such as nanotechnology, materials science, and theore...

  3. Advanced fuel chemistry for advanced engines.

    Energy Technology Data Exchange (ETDEWEB)

    Taatjes, Craig A.; Jusinski, Leonard E.; Zador, Judit; Fernandes, Ravi X.; Miller, James A.

    2009-09-01

    Autoignition chemistry is central to predictive modeling of many advanced engine designs that combine high efficiency and low inherent pollutant emissions. This chemistry, and especially its pressure dependence, is poorly known for fuels derived from heavy petroleum and for biofuels, both of which are becoming increasingly prominent in the nation's fuel stream. We have investigated the pressure dependence of key ignition reactions for a series of molecules representative of non-traditional and alternative fuels. These investigations combined experimental characterization of hydroxyl radical production in well-controlled photolytically initiated oxidation and a hybrid modeling strategy that linked detailed quantum chemistry and computational kinetics of critical reactions with rate-equation models of the global chemical system. Comprehensive mechanisms for autoignition generally ignore the pressure dependence of branching fractions in the important alkyl + O{sub 2} reaction systems; however we have demonstrated that pressure-dependent 'formally direct' pathways persist at in-cylinder pressures.

  4. Advances in quantum chemistry

    CERN Document Server

    Sabin, John R

    2013-01-01

    Advances in Quantum Chemistry presents surveys of current topics in this rapidly developing field that has emerged at the cross section of the historically established areas of mathematics, physics, chemistry, and biology. It features detailed reviews written by leading international researchers. This volume focuses on the theory of heavy ion physics in medicine.Advances in Quantum Chemistry presents surveys of current topics in this rapidly developing field that has emerged at the cross section of the historically established areas of mathematics, physics, chemistry, and biology. It features

  5. Advanced linear algebra

    CERN Document Server

    Cooperstein, Bruce

    2015-01-01

    Advanced Linear Algebra, Second Edition takes a gentle approach that starts with familiar concepts and then gradually builds to deeper results. Each section begins with an outline of previously introduced concepts and results necessary for mastering the new material. By reviewing what students need to know before moving forward, the text builds a solid foundation upon which to progress. The new edition of this successful text focuses on vector spaces and the maps between them that preserve their structure (linear transformations). Designed for advanced undergraduate and beginning graduate stud

  6. Whither Advanced Placement?

    Directory of Open Access Journals (Sweden)

    William Lichten

    2000-06-01

    Full Text Available This is a review of the Advanced Placement (AP Program. In disagreement with claims of the College Board, there is firm evidence that the average test performance level has dropped. The College Board's scale and claims for AP qualification disagree seriously with college standards. A majority of tests taken do not qualify. It appears that "advanced placement" is coming closer to "placement." This article recommends that the College Board's policy of concentrating on numbers of participants should be changed to an emphasis on student performance and program quality.

  7. Advanced number theory

    CERN Document Server

    Cohn, Harvey

    1980-01-01

    ""A very stimulating book ... in a class by itself."" - American Mathematical MonthlyAdvanced students, mathematicians and number theorists will welcome this stimulating treatment of advanced number theory, which approaches the complex topic of algebraic number theory from a historical standpoint, taking pains to show the reader how concepts, definitions and theories have evolved during the last two centuries. Moreover, the book abounds with numerical examples and more concrete, specific theorems than are found in most contemporary treatments of the subject.The book is divided into three parts

  8. MR Neurography: Advances

    Directory of Open Access Journals (Sweden)

    Avneesh Chhabra

    2013-01-01

    Full Text Available High resolution and high field magnetic resonance neurography (MR neurography, MRN is shown to have excellent anatomic capability. There have been considerable advances in the technology in the last few years leading to various feasibility studies using different structural and functional imaging approaches in both clinical and research settings. This paper is intended to be a useful seminar for readers who want to gain knowledge of the advancements in the MRN pulse sequences currently used in clinical practice as well as learn about the other techniques on the horizon aimed at better depiction of nerve anatomy, pathology, and potential noninvasive evaluation of nerve degeneration or regeneration.

  9. Advances in catalysis

    CERN Document Server

    Gates, Bruce C

    2012-01-01

    Advances in Catalysis fills the gap between the journal papers and the textbooks across the diverse areas of catalysis research. For more than 60 years Advances in Catalysis has been dedicated to recording progress in the field of catalysis and providing the scientific community with comprehensive and authoritative reviews. This series in invaluable to chemical engineers, physical chemists, biochemists, researchers and industrial chemists working in the fields of catalysis and materials chemistry. * In-depth, critical, state-of-the-art reviews * Comprehensive, covers of all as

  10. Advances in catalysis

    CERN Document Server

    Jentoft, Friederike C

    2014-01-01

    Advances in Catalysis fills the gap between the journal papers and the textbooks across the diverse areas of catalysis research. For more than 60 years Advances in Catalysis has been dedicated to recording progress in the field of catalysis and providing the scientific community with comprehensive and authoritative reviews. This series is invaluable to chemical engineers and chemists working in the field of catalysis in academia or industry. Authoritative reviews written by experts in the field. Topics selected to reflect progress of the field. Insightful and critical articles, fully edite

  11. Advanced router architectures

    CERN Document Server

    Kloth, Axel K

    2005-01-01

    Routers, switches, and transmission equipment form the backbone of the Internet, yet many users and service technicians do not understand how these nodes really work.Advanced Router Architectures addresses how components of advanced routers work together and how they are integrated with each other. This book provides the background behind why these building blocks perform certain functions, and how the function is implemented in general use. It offers an introduction to the subject matter that is intended to trigger deeper interest from the reader. The book explains, for example, why traffic m

  12. Advancing cardiovascular tissue engineering

    Science.gov (United States)

    Truskey, George A.

    2016-01-01

    Cardiovascular tissue engineering offers the promise of biologically based repair of injured and damaged blood vessels, valves, and cardiac tissue. Major advances in cardiovascular tissue engineering over the past few years involve improved methods to promote the establishment and differentiation of induced pluripotent stem cells (iPSCs), scaffolds from decellularized tissue that may produce more highly differentiated tissues and advance clinical translation, improved methods to promote vascularization, and novel in vitro microphysiological systems to model normal and diseased tissue function. iPSC technology holds great promise, but robust methods are needed to further promote differentiation. Differentiation can be further enhanced with chemical, electrical, or mechanical stimuli. PMID:27303643

  13. Advanced Surface Technology

    DEFF Research Database (Denmark)

    Møller, Per; Nielsen, Lars Pleht

    This new significant book on advanced modern surface technology in all its variations, is aimed at both teaching at engineering schools and practical application in industry. The work covers all the significant aspects of modern surface technology and also describes how new advanced techniques make...... the components. It covers everything from biocompatible surfaces of IR absorbent or reflective surfaces to surfaces with specific properties within low friction, hardness, corrosion, colors, etc. The book includes more than 400 pages detailing virtually all analysis methods for examining at surfaces....

  14. Advances in chemical physics

    CERN Document Server

    Rice, Stuart A

    2014-01-01

    Advances in Chemical Physics is the only series of volumes available that explores the cutting edge of research in chemical physics. This is the only series of volumes available that presents the cutting edge of research in chemical physics.Includes contributions from experts in this field of research.Contains a representative cross-section of research that questions established thinking on chemical solutions.Structured with an editorial framework that makes the book an excellent supplement to an advanced graduate class in physical chemistry or chemical physics.

  15. Advances in microwaves 3

    CERN Document Server

    Young, Leo

    2013-01-01

    Advances in Microwaves, Volume 3 covers the advances and applications of microwave signal transmission and Gunn devices. This volume contains six chapters and begins with descriptions of ground-station antennas for space communications. The succeeding chapters deal with beam waveguides, which offer interesting possibilities for transmitting microwave energy, as well as with parallel or tubular beams from antenna apertures. A chapter discusses the electron transfer mechanism and the velocity-field characteristics, with a particular emphasis on the microwave properties of Gunn oscillators. The l

  16. Advanced Containment System

    Science.gov (United States)

    Kostelnik, Kevin M.; Kawamura, Hideki; Richardson, John G.; Noda, Masaru

    2005-02-08

    An advanced containment system for containing buried waste and associated leachate. The advanced containment system comprises a plurality of casing sections with each casing section interlocked to an adjacent casing section. Each casing section includes a complementary interlocking structure that interlocks with the complementary interlocking structure on an adjacent casing section. A barrier filler substantially fills the casing sections and may substantially fill the spaces of the complementary interlocking structure to form a substantially impermeable barrier. Some of the casing sections may include sensors so that the casing sections and the zone of interest may be remotely monitored after the casing sections are emplaced in the ground.

  17. Advanced Analysis Environments - Summary

    International Nuclear Information System (INIS)

    This is a summary of the panel discussion on Advanced Analysis Environments. Rene Brun, Tony Johnson, and Lassi Tuura shared their insights about the trends and challenges in analysis environments. This paper contains the initial questions, a summary of the speakers' presentation, and the questions asked by the audience

  18. Advances in satellite oceanography

    Science.gov (United States)

    Brown, O. B.; Cheney, R. E.

    1983-01-01

    Technical advances and recent applications of active and passive satellite remote sensing techniques to the study of oceanic processes are summarized. The general themes include infrared and visible radiometry, active and passive microwave sensors, and buoy location systems. The surface parameters of sea surface temperature, windstream, sea state, altimetry, color, and ice are treated as applicable under each of the general methods.

  19. Advanced Distribution Management System

    Science.gov (United States)

    Avazov, Artur R.; Sobinova, Liubov A.

    2016-02-01

    This article describes the advisability of using advanced distribution management systems in the electricity distribution networks area and considers premises of implementing ADMS within the Smart Grid era. Also, it gives the big picture of ADMS and discusses the ADMS advantages and functionalities.

  20. Advanced Biosignal Processing

    CERN Document Server

    Nait-Ali, Amine

    2009-01-01

    Presents the principle of many advanced biosignal processing techniques. This title introduces the main biosignal properties and the acquisition techniques. It concerns one of the most intensively used biosignals in the clinical routine, namely the Electrocardiogram, the Elektroenzephalogram, the Electromyogram and the Evoked Potential

  1. Advances in satellite communications

    CERN Document Server

    Minoli, Daniel

    2015-01-01

    Discussing advances in modulation techniques and HTS spotbeam technologiesSurveying emerging high speed aeronautical mobility services and maritime and other terrestrial mobility servicesAssessing M2M (machine-to-machine) applications, emerging Ultra HD video technologies and new space technology

  2. Advances in Environmental Psychology

    OpenAIRE

    Nasar, Jack L.

    2015-01-01

    When Plenum stopped publishing its edited series—Human Behavior and Environment and Advances in Environment, Behavior and Design—the field of environmental psychology suffered a loss. Scholars could go to one of the edited Plenum books to find state-of-the-art reviews on existing and emerging areas of research. [...

  3. Advanced nuclear propulsion concepts

    Energy Technology Data Exchange (ETDEWEB)

    Howe, S.D. [Los Alamos National Lab., NM (United States)

    1994-12-31

    A preliminary analysis has been carried out for two potential advanced nuclear propulsion systems: a contained pulsed nuclear propulsion engine and an antiproton initiated ICF system. The results of these studies indicate that both concepts have a high potential to help enable manned planetary exploration but require substantial development.

  4. Technological advances transforming rheumatology

    OpenAIRE

    Robinson, William H.; Mao, Rong

    2015-01-01

    Technological advances over the past decade have revolutionized many areas of rheumatology, ranging from diagnosis, prognosis and therapeutic development to the mechanistic understanding of rheumatic diseases. This overview highlights key technological innovations and discusses the major impact that these developments are having on research and clinical practice.

  5. Advanced Control Engineering

    DEFF Research Database (Denmark)

    Zhou, Jianjun

    1999-01-01

    This book is developed as a textbook for the course Advanced Control Engineering. The book is intended for students in mechanical engineering and its aim is to provide an understanding of modern control theory as well as methodologies and applications for state space modeling and design. For this...

  6. Methodological Advances in Dea

    NARCIS (Netherlands)

    L. Cherchye (Laurens); G.T. Post (Thierry)

    2001-01-01

    textabstractWe survey the methodological advances in DEA over the last 25 years and discuss the necessary conditions for a sound empirical application. We hope this survey will contribute to the further dissemination of DEA, the knowledge of its relative strengths and weaknesses, and the tools curre

  7. Advanced Plant Habitat (APH)

    Science.gov (United States)

    Richards, Stephanie E. (Compiler); Levine, Howard G.; Reed, David W.

    2016-01-01

    The Advanced Plant Habitat (APH) hardware will be a large growth volume plant habitat, capable of hosting multigenerational studies, in which environmental variables (e.g., temperature, relative humidity, carbon dioxide level light intensity and spectral quality) can be tracked and controlled in support of whole plant physiological testing and Bio-regenerative Life Support System investigations.

  8. THE ADVANCED STELLAR COMPASS

    DEFF Research Database (Denmark)

    Jørgensen, John Leif; Liebe, Carl Christian

    1997-01-01

    demand the Advanced Stellar Compass (ASC), a fully autonomous miniature star tracker, was developed. This ASC is capable of both solving the "lost in space" problem and determine the attitude with arcseconds precision. The development, principles of operation and instrument autonomy of the ASC is...

  9. Advanced instrumentation and teleoperation

    International Nuclear Information System (INIS)

    SCK-CEN's advanced instrumentation and teleoperation project aims at evaluating the potential of a telerobotic approach in a nuclear environment and, in particular, the use of remote-perception systems. Main achievements in 1997 in the areas of R and D on radiation tolerance for remote sensing, optical fibres and optical-fibre sensors, and computer-aided teleoperation are reported

  10. Advanced Chemical Propulsion

    Science.gov (United States)

    Alexander, L.

    2004-11-01

    Improving the performance and reliability characteristics of chemical propulsion systems requires research and testing of higher-performance propellants, higher efficiency thrusters, cryogenics technology, lightweight components and advancements in propulsion system design and assessment. Propellants are being investigated to identify practical combinations with higher efficiencies and better thermal properties to reduce thermal control requirements. This includes combinations with modest increases, such as LOX-hydrazine, as well as a new evaluation of major improvements available from fluorine-bearing oxidizers. Practical ways of implementing cryogenic propulsion to further increase efficiency are also being studied. Some potential advances include small pump-fed engines, and improvements in cryocooler technology and tank pressure control. Gelled propellants will be tested to determine the practicality of letting propellants freeze at low environmental temperatures and thawing them only when required for use. The propellant tank is typically the single highest non-expendable mass in a chemical propulsion system. Lightweight tank designs, materials and methods of fabrication are being investigated. These are projected to offer a 45-50 percent decrease in tank mass, representing the potential inert system mass savings. Mission and systems analyses are being conducted to guide the technology research and set priorities for technology investment, based on estimated gains in payload and mission capabilities. This includes development of advanced assessment tools and analyses of specific missions selected from Science Missions' Directorate. The goal is to mature a suite of reliable advanced propulsion technologies that will promote more cost efficient missions through the reduction of interplanetary trip time, increased scientific payload mass fraction and longer on-station operations. This talk will review the Advanced Chemical technology development roadmap, current

  11. Advanced CCD camera developments

    Energy Technology Data Exchange (ETDEWEB)

    Condor, A. [Lawrence Livermore National Lab., CA (United States)

    1994-11-15

    Two charge coupled device (CCD) camera systems are introduced and discussed, describing briefly the hardware involved, and the data obtained in their various applications. The Advanced Development Group Defense Sciences Engineering Division has been actively designing, manufacturing, fielding state-of-the-art CCD camera systems for over a decade. These systems were originally developed for the nuclear test program to record data from underground nuclear tests. Today, new and interesting application for these systems have surfaced and development is continuing in the area of advanced CCD camera systems, with the new CCD camera that will allow experimenters to replace film for x-ray imaging at the JANUS, USP, and NOVA laser facilities.

  12. Advances in atomic spectroscopy

    CERN Document Server

    Sneddon, J

    1998-01-01

    This volume continues the series'' cutting-edge reviews on developments in this field. Since its invention in the 1920s, electrostatic precipitation has been extensively used in industrial hygiene to remove dust and particulate matter from gases before entering the atmosphere. This combination of electrostatic precipitation is reported upon in the first chapter. Following this, chapter two reviews recent advances in the area of chemical modification in electrothermal atomization. Chapter three consists of a review which deal with advances and uses of electrothermal atomization atomic absorption spectrometry. Flow injection atomic spectroscopy has developed rapidly in recent years and after a general introduction, various aspects of this technique are looked at in chapter four. Finally, in chapter five the use of various spectrometric techniques for the determination of mercury are described.

  13. Advances in soil dynamics

    DEFF Research Database (Denmark)

    Advances in Soil Dynamics, Volume 3, represents the culmination of the work undertaken by the Advances in Soil Dynamics Monograph Committee, PM-45-01, about 15 years ago to summarize important developments in this field over the last 35 years. When this project was initiated, the main goal was to...... abridge major strides made in the general area of soil dynamics during the sixties, seventies, and eighties. However, by about the mid-nineties soil dynamics research in the US and much of the developed world had come to a virtual standstill. Although significant progress was made prior to the mid......-nineties, we still do not have a sound fundamental knowledge of soil-machine and soil-plant interactions. It is the hope of the editors that these three volumes will provide a ready reference for much needed future research in this area....

  14. Advanced information processing system

    Science.gov (United States)

    Lala, J. H.

    1984-01-01

    Design and performance details of the advanced information processing system (AIPS) for fault and damage tolerant data processing on aircraft and spacecraft are presented. AIPS comprises several computers distributed throughout the vehicle and linked by a damage tolerant data bus. Most I/O functions are available to all the computers, which run in a TDMA mode. Each computer performs separate specific tasks in normal operation and assumes other tasks in degraded modes. Redundant software assures that all fault monitoring, logging and reporting are automated, together with control functions. Redundant duplex links and damage-spread limitation provide the fault tolerance. Details of an advanced design of a laboratory-scale proof-of-concept system are described, including functional operations.

  15. CANDU advanced fuel cycles

    International Nuclear Information System (INIS)

    This report is based on informal lectures and presentations made on CANDU Advanced Fuel Cycles over the past year or so, and discusses the future role of CANDU in the changing environment for the Canadian and international nuclear power industry. The changing perspectives of the past decade lead to the conclusion that a significant future market for a CANDU advanced thermal reactor will exist for many decades. Such a reactor could operate in a stand-alone strategy or integrate with a mixed CANDU-LWR or CANDU-FBR strategy. The consistent design focus of CANDU on enhanced efficiency of resource utilization combined with a simple technology to achieve economic targets, will provide sufficient flexibility to maintain CANDU as a viable power producer for both the medium- and long-term future

  16. Advances in capillary electrophoresis

    International Nuclear Information System (INIS)

    In the 1980s, capillary electrophoresis (CE) developed rapidly into a first-class analytical separation technique. Its advances in instru-mentation and method development will not only enhance or complement existing mature separation techniques such as liquid chromatography and conventional slab gel electrophoresis, but will also severely challenge these separation methods. A brief overview of most striking achievement of CE in the 1980s is given, which illustrates the challenge to liquid chromatography and conventional slab gel electrophoresis, and some detailed discussions are presented to highlight the advantages of CE. New developments in CE that can be expected for the 1990s include especially column technology, separation chemistry and instrumentation, which will serve further to diversify and improve the applicability of this technique in areas which are poorly addressed by other separation methods. This paper considers and speculates on the technological advancements that can be expected to emerge for CE in the 1990s. (author). 95 refs.; 14 figs

  17. Advanced far infrared detectors

    International Nuclear Information System (INIS)

    Recent advances in photoconductive and bolometric semiconductor detectors for wavelength 1 mm > λ > 50 μm are reviewed. Progress in detector performance in this photon energy range has been stimulated by new and stringent requirements for ground based, high altitude and space-borne telescopes for astronomical and astrophysical observations. The paper consists of chapters dealing with the various types of detectors: Be and Ga doped Ge photoconductors, stressed Ge:Ga devices and neutron transmutation doped Ge thermistors. Advances in the understanding of basic detector physics and the introduction of modern semiconductor device technology have led to predictable and reliable fabrication techniques. Integration of detectors into functional arrays has become feasible and is vigorously pursued by groups worldwide

  18. Advanced Agriculture system

    Directory of Open Access Journals (Sweden)

    Shrinivas R. Zanwar

    2012-05-01

    Full Text Available This article addresses the advanced system which improves agriculture processes like cultivation on ploughed land, based on robotic platform. We have developed a robotic vehicle having four wheels and steered by DC motor. The advanced autonomous system architecture gives us the opportunity to develop a complete new range of agricultural equipment based on small smart machines. The machine will cultivate the farm by considering particular rows and specific column at fixed distance depending on crop. The obstacle detection problem will also be considered, sensed by infrared sensor. The whole algorithm, calculation, processing, monitoring are designed with motors & sensor interfaced with microcontroller. The result obtained through example activation unit is also presented. The dc motor simulation with feedforward and feedback technique shows precise output. With the help of two examples, a DC motor and a magnetic levitation system, the use of MATLAB and Simulink for modeling, analysis and control is designed.

  19. Advanced intelligent systems

    CERN Document Server

    Ryoo, Young; Jang, Moon-soo; Bae, Young-Chul

    2014-01-01

    Intelligent systems have been initiated with the attempt to imitate the human brain. People wish to let machines perform intelligent works. Many techniques of intelligent systems are based on artificial intelligence. According to changing and novel requirements, the advanced intelligent systems cover a wide spectrum: big data processing, intelligent control, advanced robotics, artificial intelligence and machine learning. This book focuses on coordinating intelligent systems with highly integrated and foundationally functional components. The book consists of 19 contributions that features social network-based recommender systems, application of fuzzy enforcement, energy visualization, ultrasonic muscular thickness measurement, regional analysis and predictive modeling, analysis of 3D polygon data, blood pressure estimation system, fuzzy human model, fuzzy ultrasonic imaging method, ultrasonic mobile smart technology, pseudo-normal image synthesis, subspace classifier, mobile object tracking, standing-up moti...

  20. Advances in Alcoholism Treatment

    OpenAIRE

    Huebner, Robert B.; Kantor, Lori Wolfgang

    2011-01-01

    Researchers are working on numerous and varied approaches to improving the accessibility, quality, effectiveness, and cost-effectiveness of treatment for alcohol use disorders (AUDs). This overview article summarizes the approaches reviewed in this issue, including potential future developments for alcoholism treatment, such as medications development, behavioral therapy, advances in technology that are being used to improve treatment, integrated care of patients with AUDs and co-occurring di...

  1. Credentialing advanced level practice

    OpenAIRE

    Costa, M. H.; Shulman, R; Bates, I

    2012-01-01

    Aim: To evaluate the impact of a prototype credentialing process, for pharmacists in advanced levels of practice, by assessing the practitioner candidates' feedback on the overall experience and the impact it had on their professional roles and career perspectives. Design: The UKCPA Critical Care Group have produced and piloted a credentialing process which has been run for three years. Opinions and perceptions from the candidates involved in the assessment days will be useful for future a...

  2. Recent Advances in Voltammetry

    OpenAIRE

    Batchelor-McAuley, Christopher; Kätelhön, Enno; Barnes, Edward O; Compton, Richard G.; Laborda, Eduardo; Molina, Angela

    2015-01-01

    Recent progress in the theory and practice of voltammetry is surveyed and evaluated. The transformation over the last decade of the level of modelling and simulation of experiments has realised major advances such that electrochemical techniques can be fully developed and applied to real chemical problems of distinct complexity. This review focuses on the topic areas of: multistep electrochemical processes, voltammetry in ionic liquids, the development and interpretation of theories of electr...

  3. Advances in electroanalytical chemistry

    OpenAIRE

    Wang, Yijun; Compton, Richard

    2012-01-01

    This thesis concerns several advances in electroanalytical chemistry which are separated into four parts: the electrochemical investigation of diffusional behaviour, the mechanistic and kinetic study of electrochemistry with room temperature ionic liquids (RTILs), the study of weakly-supported electrochemistry and a comparison of the Butler-Volmer and Marcus-Hush kinetic theories of electron transfer. A study of the diffusional behaviour of electroactive species is essential for further s...

  4. Advances in microwaves 7

    CERN Document Server

    Young, Leo

    2013-01-01

    Advances in Microwaves, Volume 7 covers the developments in the study of microwaves. The book discusses the effect of surface roughness on the propagation of the TEM mode, as well as the voltage breakdown of microwave antennas. The text also describes the theory and design considerations of single slotted-waveguide linear arrays and the techniques and theories that led to the achievement of wide bandwidths and ultralow noise temperatures for communication applications. The book will prove invaluable to microwave engineers.

  5. Advanced Small Rechargeable Batteries

    Science.gov (United States)

    Halpert, Gerald

    1989-01-01

    Lithium-based units offer highest performance. Paper reviews status of advanced, small rechargeable batteries. Covers aqueous systems including lead/lead dioxide, cadmium/nickel oxide, hydrogen/nickel oxide, and zinc/nickel oxide, as well as nonaqueous systems. All based on lithium anodes, nonaqueous systems include solid-cathode cells (lithium/molybdenum disulfide, lithium/titanium disulfide, and lithium/vanadium oxide); liquid-cathode cells (lithium/sulfur dioxide cells); and new category, lithium/polymer cells.

  6. Advanced superconducting materials

    International Nuclear Information System (INIS)

    The superconducting properties of various materials are reviewed in view of their use in high field magnets. The critical current densities above 12 T of conductors based on NbN or PbMo6S8 are compared to those of the most advanced practical conductors based on alloyed by Nb3Sn. Different aspects of the mechanical reinforcement of high field conductors, rendered necessary by the strong Lorentz forces (e.g. in fusion magnets), are discussed. (orig.)

  7. Advanced worker protection system

    International Nuclear Information System (INIS)

    The Department of Energy (DOE) is in the process of defining the magnitude and diversity of Decontamination and Decommissioning (D ampersand D) obligations at its numerous sites. The DOE believes that existing technologies are inadequate to solve many challenging problems such as how to decontaminate structures and equipment cost effectively, what to do with materials and wastes generated, and how to adequately protect workers and the environment. Preliminary estimates show a tremendous need for effective use of resources over a relatively long period (over 30 years). Several technologies are being investigated which can potentially reduce D ampersand D costs while providing appropriate protection to DOE workers. The DOE recognizes that traditional methods used by the EPA in hazardous waste site clean up activities are insufficient to provide the needed protection and worker productivity demanded by DOE D ampersand D programs. As a consequence, new clothing and equipment which can adequately protect workers while providing increases in worker productivity are being sought for implementation at DOE sites. This project will result in the development of an Advanced Worker Protection System (AWPS). The AWPS will be built around a life support backpack that uses liquid air to provide cooling as well as breathing gas to the worker. The backpack will be combined with advanced protective garments, advanced liquid cooling garment, respirator, communications, and support equipment to provide improved worker protection, simplified system maintenance, and dramatically improve worker productivity through longer duration work cycles. Phase I of the project has resulted in a full scale prototype Advanced Worker Protection Ensemble (AWPE, everything the worker will wear), with sub-scale support equipment, suitable for integrated testing and preliminary evaluation. Phase II will culminate in a full scale, certified, pre-production AWPS and a site demonstration

  8. 6 Sigma project advance

    International Nuclear Information System (INIS)

    This book deals with 6 sigma project advance which introduces 6 sigma project in Changwon special steel, how is failure accepted? CTQ selection which is starting line, definition of performance standard, measurement system check on reliability of measurement data, check of process capacity for current level, establishment of target, optimal design and performance of application, practice of management system for maintain of improved result, CTQ selection, check of measurement system and practice of management system.

  9. Advances in geophysics

    CERN Document Server

    Sato, Haruo

    2013-01-01

    The critically acclaimed serialized review journal for over 50 years, Advances in Geophysics is a highly respected publication in the field of geophysics. Since 1952, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. Now in its 54th volume, it contains much material still relevant today--truly an essential publication for researchers in all fields of geophysics.Key features: * Contributions from leading authorities * Informs and updates on all the latest developments in the field

  10. Silicene: Recent theoretical advances

    KAUST Repository

    Lew Yan Voon, L. C.

    2016-04-14

    Silicene is a two-dimensional allotrope of silicon with a puckered hexagonal structure closely related to the structure of graphene and that has been predicted to be stable. To date, it has been successfully grown in solution (functionalized) and on substrates. The goal of this review is to provide a summary of recent theoretical advances in the properties of both free-standing silicene as well as in interaction with molecules and substrates, and of proposed device applications.

  11. Advances in bioethanol

    CERN Document Server

    Bajpai, Pratima

    2013-01-01

    The book provides an updated and detailed overview on advances in bioethanol. It looks at the historical perspectives, chemistry, sources and production of ethanol and discusses biotechnology breakthroughs and promising developments. The book also provides the details regarding the uses, advantages, problems, environmental effects and characteristics of bioethanol as a fuel. In addition, it presents information about ethanol in different parts of the world and also highlights the challenges and future of ethanol.

  12. Advances in Male Contraception

    OpenAIRE

    Page, Stephanie T; Amory, John K.; Bremner, William J.

    2008-01-01

    Despite significant advances in contraceptive options for women over the last 50 yr, world population continues to grow rapidly. Scientists and activists alike point to the devastating environmental impacts that population pressures have caused, including global warming from the developed world and hunger and disease in less developed areas. Moreover, almost half of all pregnancies are still unwanted or unplanned. Clearly, there is a need for expanded, reversible, contraceptive options. Multi...

  13. Advanced Environmental Monitoring Technologies

    Science.gov (United States)

    Jan, Darrell

    2004-01-01

    Viewgraphs on Advanced Environmental Monitoring Technologies are presented. The topics include: 1) Monitoring & Controlling the Environment; 2) Illustrative Example: Canary 3) Ground-based Commercial Technology; 4) High Capability & Low Mass/Power + Autonomy = Key to Future SpaceFlight; 5) Current Practice: in Flight; 6) Current Practice: Post Flight; 7) Miniature Mass Spectrometer for Planetary Exploration and Long Duration Human Flight; 8) Hardware and Data Acquisition System; 9) 16S rDNA Phylogenetic Tree; and 10) Preview of Porter.

  14. Nanoplasmonics advanced device applications

    CERN Document Server

    Chon, James W M

    2013-01-01

    Focusing on control and manipulation of plasmons at nanometer dimensions, nanoplasmonics combines the strength of electronics and photonics, and is predicted to replace existing integrated circuits and photonic devices. It is one of the fastest growing fields of science, with applications in telecommunication, consumer electronics, data storage, medical diagnostics, and energy.Nanoplasmonics: Advanced Device Applications provides a scientific and technological background of a particular nanoplasmonic application and outlines the progress and challenges of the application. It reviews the latest

  15. Advanced Intranet Search Engine

    OpenAIRE

    Narayan, Nitesh

    2009-01-01

    Information retrieval has been a prevasive part of human society since its existence.With the advent of internet and World wide Web it became an extensive area of researchand major foucs, which lead to development of various search engines to locate the de-sired information, mostly for globally connected computer networks viz. internet.Butthere is another major part of computer network viz. intranet, which has not seen muchof advancement in information retrieval approaches, in spite of being ...

  16. Advances in Laryngoscopy

    OpenAIRE

    Michael Aziz

    2015-01-01

    Recent technological advances have made airway management safer. Because difficult intubation remains challenging to predict, having tools readily available that can be used to manage a difficult airway in any setting is critical. Fortunately, video technology has resulted in improvements for intubation performance while using laryngoscopy by various means. These technologies have been applied to rigid optical stylets, flexible intubation scopes, and, most notably, rigid laryngoscopes. These ...

  17. Advances in photovoltaic technology

    Science.gov (United States)

    Landis, G. A.; Bailey, S. G.

    1992-01-01

    The advances in solar cell efficiency, radiation tolerance, and cost in the last 10 years are presented. The potential performance of thin-film solar cells in space is examined, and the cost and the historical trends in production capability of the photovoltaics industry are considered with respect to the needs of satellite solar power systems. Attention is given to single-crystal cells, concentrator and cascade cells, and thin-film solar cells.

  18. Advances in Crash Response

    Centers for Disease Control (CDC) Podcasts

    2009-06-29

    In this podcast, Dr. Richard C. Hunt, Director of CDC's Division of Injury Response, provides an overview on the benefits of using an Advanced Automatic Collision Notification system, or AACN, to help with emergency triage of people injured in vehicle crashes.  Created: 6/29/2009 by National Center for Injury Prevention and Control (NCIPC), Division of Injury Response (DIR).   Date Released: 6/29/2009.

  19. Advanced coated particle fuels

    International Nuclear Information System (INIS)

    The coated particle fuel (cpf) has been developed for use in high-temperature gas-cooled reactors, but it may find applications in other types of reactors. In JAERI, besides the development of cpf for High Temperature Engineering Test Reactor, conceptual studies of the cpf applications in actinide burner reactors and space reactors have been made. The conceptual design studies as well as the research and development of advanced coatings, ZrC and TiN, are reviewed. (author)

  20. Advances in burn treatment

    OpenAIRE

    Lahoda, LU; Vogt, PM

    2006-01-01

    The German-speaking burn specialist, organized in the DAV (Deutsche Arbeitsgemeinschaft für Verbrennungsmedizin) held their yearly meeting in 2004 in Rottach-Egern, Bavaria. Participants from Switzerland, Germany and Austria found a high standing, very well organized and thorough program summoned by the host, Dr. Guido Graf Henckel von Donnersmarck, Munich. The topics consisted of reconstructive surgery, skin substitutes and replacement, advances in burn medicine over the last 10 years and bu...

  1. Advances in geophysics

    CERN Document Server

    Sato, Haruo

    2012-01-01

    The critically acclaimed serialized review journal for over 50 years, Advances in Geophysics is a highly respected publication in the field of geophysics. Since 1952, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. Now in its 52nd volume, it contains much material still relevant today--truly an essential publication for researchers in all fields of geophysics.Key features: * Contributions from leading authorities * Informs and updates on all the latest developments in the field

  2. Machinability of advanced materials

    CERN Document Server

    Davim, J Paulo

    2014-01-01

    Machinability of Advanced Materials addresses the level of difficulty involved in machining a material, or multiple materials, with the appropriate tooling and cutting parameters.  A variety of factors determine a material's machinability, including tool life rate, cutting forces and power consumption, surface integrity, limiting rate of metal removal, and chip shape. These topics, among others, and multiple examples comprise this research resource for engineering students, academics, and practitioners.

  3. Advances in microwaves 8

    CERN Document Server

    Young, Leo

    2013-01-01

    Advances in Microwaves, Volume 8 covers the developments in the study of microwaves. The book discusses the circuit forms for microwave integrated circuits; the analysis of microstrip transmission lines; and the use of lumped elements in microwave integrated circuits. The text also describes the microwave properties of ferrimagnetic materials, as well as their interaction with electromagnetic waves propagating in bounded waveguiding structures. The integration techniques useful at high frequencies; material technology for microwave integrated circuits; specific requirements on technology for d

  4. Advanced Accelerator Concepts

    International Nuclear Information System (INIS)

    This conference proceedings represent the results of theThird Advanced Accelerator Concepts Workshop held in PortJefferson, New York. The workshop was sponsored by the U.S.Department of Energy, the Office of Navel Research and BrookhavenNational Laboratory. The purpose was to assess new techniques forproduction of ultra-high gradient acceleration and to addressengineering issues in achieving this goal. There are eighty-onepapers collected in the proceedings and all have been abstractedfor the database

  5. Advanced Microturbine Systems

    Energy Technology Data Exchange (ETDEWEB)

    Lindberg, Laura [Honeywell International Inc., Phoenix, AZ (United States)

    2005-04-29

    Dept. of Energy (DOE) Cooperative Agreement DE-FC02-00-CH11061 was originally awarded to Honeywell International, Inc. Honeywell Power Systems Inc. (HPSI) division located in Albuquerque, NM in October 2000 to conduct a program titled Advanced Microturbine Systems (AMS). The DOE Advanced Microturbines Systems Program was originally proposed as a five-year program to design and develop a high efficiency, low emissions, durable microturbine system. The period of performance was to be October 2000 through September 2005. Program efforts were underway, when one year into the program Honeywell sold the intellectual property of Honeywell Power Systems Inc. and HPSI ceased business operations. Honeywell made an internal decision to restructure the existing program due to the HPSI shutdown and submitted a formal request to DOE on September 24, 2001 to transfer the Cooperative Agreement to Honeywell Engines, Systems and Services (HES&S) in Phoenix, AZ in order to continue to offer support for DOE's Advanced Microturbine Program. Work continued on the descoped program under Cooperative Agreement No. DE-FC26-00-CH11061 and has been completed.

  6. Advanced SLARette delivery machine

    International Nuclear Information System (INIS)

    SLARette 1 equipment, comprising of a SLARette Delivery Machine, SLAR Tools, SLAR power supplies and SLAR Inspection Systems was designed, developed and manufactured to service fuel channels of CANDU 6 stations during the regular yearly station outages. The Mark 2 SLARette Delivery Machine uses a Push Tube system to provide the axial and rotary movements of the SLAR Tool. The Push Tubes are operated remotely but must be attached and removed manually. Since this operation is performed at the Reactor face, there is radiation dose involved for the workers. An Advanced SLARette Delivery Machine which incorporates a computer controlled telescoping Ram in the place of the Push Tubes has been recently designed and manufactured. Utilization of the Advanced SLARette Delivery Machine significantly reduces the amount of radiation dose picked up by the workers because the need to have workers at the face of the Reactor during the SLARette operation is greatly reduced. This paper describes the design, development and manufacturing process utilized to produce the Advanced SLARette Delivery Machine and the experience gained during the Gentilly-2 NGS Spring outage. (author)

  7. Advanced CANDU control centre

    International Nuclear Information System (INIS)

    The CANDU 9 design is based upon the 900 MWe class Darlington station in Canada, which is among the world leading nuclear power stations for capacity factor with low operation, maintenance and administration costs. The CANDU 9 design provides an advanced control centre with enhanced operations features. The advanced AECL control centre design includes the proven functionality of existing CANDU control centres, those implementable characteristics identified by systematic design combined with a human factors analysis of operations requirements and features needed to improve station operability which are made possible by the application of current technology. The design strategy is to preserve the general main control room operations staff work area as unchanged as possible to facilitate the inclusion of past features and operational experience while incorporating operability improvements. The author will present those features of the advanced CANDU control centre which facilitates improved operability capabilities. As well, aspects of the design process utilized, application of simulation technology and conclusions regarding this design approach will be reviewed

  8. Fusion advanced studies Torus

    International Nuclear Information System (INIS)

    The successful development of ITER and DEMO scenarios requires preparatory activities on devices that are smaller than ITER, sufficiently flexible and capable of investigating the peculiar physics of burning plasma conditions. The aim of the Fusion Advanced Studies Torus (FAST) proposal [2.1] (formerly FT3 [2.2]) is to show that the preparation of ITER scenarios and the development of new expertise for the DEMO design and RD can be effectively implemented on a new facility. FAST will a) operate with deuterium plasmas, thereby avoiding problems associated with tritium, and allow investigation of nonlinear dynamics (which are important for understanding alpha particle behaviour in burning plasmas) by using fast ions accelerated by heating and current drive systems; b) work in a dimensionless parameter range close to that of ITER; c) test technical innovative solutions, such as full-tungsten plasma-facing components and an advanced liquid metal divertor target for the first wall/divertor, directly relevant for ITER and DEMO; d) exploit advanced regimes with a much longer pulse duration than the current diffusion time; e) provide a test bed for ITER and DEMO diagnostics; f) provide an ideal framework for model and numerical code benchmarks, their verification and validation in ITER/ DEMO-relevant plasma conditions

  9. Advanced scale conditioning agents

    International Nuclear Information System (INIS)

    A technical description of Advanced Scale Conditioning Agents (ASCA) technology was published in the May-June 2003 edition of the Nuclear Plant Journal. That article described the development of programs of advanced scale conditioning agents and specific types to maintain the secondary side of steam generators within a pressurized water reactor free of deposited corrosion products and corrosion-inducing contaminants to ensure their long-term operation. This article describes the first two plant applications of advanced scale conditioning agents implemented at Southern Nuclear Operating Company's Vogtle Units 1 and 2 during their 2002 scheduled outages to minimize tube degradation and maintain full power operation using the most effective techniques while minimizing outage costs. The goal was to remove three to four fuel cycles of deposits from each steam generator so that after future chemical cleaning activities, ASCAs could be used to maintain the cleanliness of the steam generators without the need for additional chemical cleaning efforts. The goal was achieved as well as several other benefits that resulted in cost savings to the plant

  10. Broadband Advanced Spectral System Project

    Data.gov (United States)

    National Aeronautics and Space Administration — NovaSol proposes to develop an advanced hyperspectral imaging system for earth science missions named BRASS (Broadband Advanced Spectral System). BRASS combines...

  11. Accelerating advanced-materials commercialization

    Science.gov (United States)

    Maine, Elicia; Seegopaul, Purnesh

    2016-05-01

    Long commercialization times, high capital costs and sustained uncertainty deter investment in innovation for advanced materials. With appropriate strategies, technology and market uncertainties can be reduced, and the commercialization of advanced materials accelerated.

  12. Planning Ahead: Advanced Heart Failure

    Science.gov (United States)

    ... Pressure High Blood Pressure Tools & Resources Stroke More Planning Ahead: Advanced Heart Failure Updated:Jul 7,2016 ... making your preferences known is called advance care planning. It allows you to speak for yourself, even ...

  13. Recent Advances in IOL Surgery

    Institute of Scientific and Technical Information of China (English)

    P.Ranga; Reddy; Venkateshwara; Rao; Puligala

    1993-01-01

    Tremendous progress is made in recent time in the field of Ophthalmology especially after advent of IOL implantation surgery. Recent advance in anaesthesia/lOL, designs/IOL, quotings/cantering, techniques/advances in operating microscope and advances in suture materials/needles etc. will be discussed.

  14. ADVANCED SULFUR CONTROL CONCEPTS

    Energy Technology Data Exchange (ETDEWEB)

    Apostolos A. Nikolopoulos; Santosh K. Gangwal; William J. McMichael; Jeffrey W. Portzer

    2003-01-01

    Conventional sulfur removal in integrated gasification combined cycle (IGCC) power plants involves numerous steps: COS (carbonyl sulfide) hydrolysis, amine scrubbing/regeneration, Claus process, and tail-gas treatment. Advanced sulfur removal in IGCC systems involves typically the use of zinc oxide-based sorbents. The sulfides sorbent is regenerated using dilute air to produce a dilute SO{sub 2} (sulfur dioxide) tail gas. Under previous contracts the highly effective first generation Direct Sulfur Recovery Process (DSRP) for catalytic reduction of this SO{sub 2} tail gas to elemental sulfur was developed. This process is currently undergoing field-testing. In this project, advanced concepts were evaluated to reduce the number of unit operations in sulfur removal and recovery. Substantial effort was directed towards developing sorbents that could be directly regenerated to elemental sulfur in an Advanced Hot Gas Process (AHGP). Development of this process has been described in detail in Appendices A-F. RTI began the development of the Single-step Sulfur Recovery Process (SSRP) to eliminate the use of sorbents and multiple reactors in sulfur removal and recovery. This process showed promising preliminary results and thus further process development of AHGP was abandoned in favor of SSRP. The SSRP is a direct Claus process that consists of injecting SO{sub 2} directly into the quenched coal gas from a coal gasifier, and reacting the H{sub 2}S-SO{sub 2} mixture over a selective catalyst to both remove and recover sulfur in a single step. The process is conducted at gasifier pressure and 125 to 160 C. The proposed commercial embodiment of the SSRP involves a liquid phase of molten sulfur with dispersed catalyst in a slurry bubble-column reactor (SBCR).

  15. Advances in modern cosmology

    CERN Document Server

    2011-01-01

    The twentieth century elevated our understanding of the Universe from its early stages to what it is today and what is to become of it. Cosmology is the weapon that utilizes all the scientific tools that we have created to feel less lost in the immensity of our Universe. The standard model is the theory that explains the best what we observe. Even with all the successes that this theory had, two main questions are still to be answered: What is the nature of dark matter and dark energy? This book attempts to understand these questions while giving some of the most promising advances in modern cosmology.

  16. Advances in biomedical engineering

    CERN Document Server

    Brown, J H U

    1976-01-01

    Advances in Biomedical Engineering, Volume 5, is a collection of papers that deals with application of the principles and practices of engineering to basic and applied biomedical research, development, and the delivery of health care. The papers also describe breakthroughs in health improvements, as well as basic research that have been accomplished through clinical applications. One paper examines engineering principles and practices that can be applied in developing therapeutic systems by a controlled delivery system in drug dosage. Another paper examines the physiological and materials vari

  17. Advances in microwaves

    CERN Document Server

    Young, Leo

    1967-01-01

    Advances in Microwaves, Volume 2 focuses on the developments in microwave solid-state devices and circuits. This volume contains six chapters that also describe the design and applications of diplexers and multiplexers. The first chapter deals with the parameters of the tunnel diode, oscillators, amplifiers and frequency converter, followed by a simple physical description and the basic operating principles of the solid state devices currently capable of generating coherent microwave power, including transistors, harmonic generators, and tunnel, avalanche transit time, and diodes. The next ch

  18. Electrical installation calculations advanced

    CERN Document Server

    Kitcher, Christopher

    2013-01-01

    All the essential calculations required for advanced electrical installation workThe Electrical Installation Calculations series has proved an invaluable reference for over forty years, for both apprentices and professional electrical installation engineers alike. The book provides a step-by-step guide to the successful application of electrical installation calculations required in day-to-day electrical engineering practiceA step-by-step guide to everyday calculations used on the job An essential aid to the City & Guilds certificates at Levels 2 and 3For apprentices and electrical installatio

  19. Advances in dental materials.

    Science.gov (United States)

    Vaderhobli, Ram M

    2011-07-01

    The use of materials to rehabilitate tooth structures is constantly changing. Over the past decade, newer material processing techniques and technologies have significantly improved the dependability and predictability of dental material for clinicians. The greatest obstacle, however, is in choosing the right combination for continued success. Finding predictable approaches for successful restorative procedures has been the goal of clinical and material scientists. This article provides a broad perspective on the advances made in various classes of dental restorative materials in terms of their functionality with respect to pit and fissure sealants, glass ionomers, and dental composites. PMID:21726695

  20. Advanced backend optimization

    CERN Document Server

    Touati, Sid

    2014-01-01

    This book is a summary of more than a decade of research in the area of backend optimization. It contains the latest fundamental research results in this field. While existing books are often more oriented toward Masters students, this book is aimed more towards professors and researchers as it contains more advanced subjects.It is unique in the sense that it contains information that has not previously been covered by other books in the field, with chapters on phase ordering in optimizing compilation; register saturation in instruction level parallelism; code size reduction for software pipe

  1. Advanced Polymer Processing Facility

    Energy Technology Data Exchange (ETDEWEB)

    Muenchausen, Ross E. [Los Alamos National Laboratory

    2012-07-25

    Some conclusions of this presentation are: (1) Radiation-assisted nanotechnology applications will continue to grow; (2) The APPF will provide a unique focus for radiolytic processing of nanomaterials in support of DOE-DP, other DOE and advanced manufacturing initiatives; (3) {gamma}, X-ray, e-beam and ion beam processing will increasingly be applied for 'green' manufacturing of nanomaterials and nanocomposites; and (4) Biomedical science and engineering may ultimately be the biggest application area for radiation-assisted nanotechnology development.

  2. Advances in diabetic retinopathy

    Directory of Open Access Journals (Sweden)

    Prakashchand Agarwal

    2014-01-01

    Full Text Available Diabetic retinopathy (DR is a complication of long-term diabetes mellitus (DM. Over the last 2 decades lot of work has been on early diagnosis of DR and screening programs have been designed to help the masses. Large numbers of clinical studies have been done for patients of diabetes and DR wherein the role of blood sugar control, metabolic control, role of oral medicines for DR, role of imaging, fluorescein angiography, and retinal photocoagulation has been studied. Newer treatment modalities are being devised and studied for better patient care. We discuss these issues in our review highlight and newer advances over the last few years.

  3. Advances in biomedical engineering

    CERN Document Server

    Brown, J H U

    1976-01-01

    Advances in Biomedical Engineering, Volume 6, is a collection of papers that discusses the role of integrated electronics in medical systems and the usage of biological mathematical models in biological systems. Other papers deal with the health care systems, the problems and methods of approach toward rehabilitation, as well as the future of biomedical engineering. One paper discusses the use of system identification as it applies to biological systems to estimate the values of a number of parameters (for example, resistance, diffusion coefficients) by indirect means. More particularly, the i

  4. Advances in biomedical engineering

    CERN Document Server

    Brown, J H U

    1973-01-01

    Advances in Biomedical Engineering, Volume 3, is a collection of papers that discusses circulatory system models, linguistics in computer usage, and clinical applications on patient monitoring. One paper describes the use of comparative models of overall circulatory mechanics that include models of the cardiac pump, of the vascular systems, and of the overall systems behavior. Another paper describes a model in processing medical language data that employs an explicit semantic structure, becoming the basis for the computer-based, artificial intelligence of the system. One paper cites studies b

  5. Advanced topics in biometrics

    CERN Document Server

    Li, Haizhou; Toh, Kar-Ann

    2011-01-01

    Biometrics is the study of methods for uniquely recognizing humans based on one or more intrinsic physical or behavioral traits. After decades of research activities, biometrics, as a recognized scientific discipline, has advanced considerably both in practical technology and theoretical discovery to meet the increasing need of biometric deployments. In this book, the editors provide both a concise and accessible introduction to the field as well as a detailed coverage on the unique research problems with their solutions in a wide spectrum of biometrics research ranging from voice, face, finge

  6. Advanced energy materials

    CERN Document Server

    Tiwari, Ashutosh

    2014-01-01

    An essential resource for scientists designing new energy materials for the vast landscape of solar energy conversion as well as materials processing and characterization Based on the new and fundamental research on novel energy materials with tailor-made photonic properties, the role of materials engineering has been to provide much needed support in the development of photovoltaic devices. Advanced Energy Materials offers a unique, state-of-the-art look at the new world of novel energy materials science, shedding light on the subject's vast multi-disciplinary approach The book focuses p

  7. Fractional dynamics recent advances

    CERN Document Server

    Klafter, Joseph; Metzler, Ralf

    2011-01-01

    This volume provides the latest developments in the field of fractional dynamics, which covers fractional (anomalous) transport phenomena, fractional statistical mechanics, fractional quantum mechanics and fractional quantum field theory. The contributors are selected based on their active and important contributions to their respective topics. This volume is the first of its kind that covers such a comprehensive range of topics in fractional dynamics. It will point out to advanced undergraduate and graduate students, and young researchers the possible directions of research in this subject. I

  8. Advanced uranium enrichment processes

    International Nuclear Information System (INIS)

    Three advanced Uranium enrichment processes are dealt with in the report: AVLIS (Atomic Vapour LASER Isotope Separation), MLIS (Molecular LASER Isotope Separation) and PSP (Plasma Separation Process). The description of the physical and technical features of the processes constitutes a major part of the report. If further presents comparisons with existing industrially used enrichment technologies, gives information on actual development programmes and budgets and ends with a chapter on perspectives and conclusions. An extensive bibliography of the relevant open literature is added to the different subjects discussed. The report was drawn up by the nuclear research Centre (CEA) Saclay on behalf of the Commission of the European Communities

  9. Advances in electronic materials

    CERN Document Server

    Kasper, Erich; Grimmeiss, Hermann G

    2008-01-01

    This special-topic volume, Advances in Electronic Materials, covers various fields of materials research such as silicon, silicon-germanium hetero-structures, high-k materials, III-V semiconductor alloys and organic materials, as well as nano-structures for spintronics and photovoltaics. It begins with a brief summary of the formative years of microelectronics; now the keystone of information technology. The latter remains one of the most important global technologies, and is an extremely complex subject-area. Although electronic materials are primarily associated with computers, the internet

  10. Advanced materials-2003

    International Nuclear Information System (INIS)

    The 8th International Symposium on Advanced Materials (ISAM) was held from 8-11 September, 2003. The proceeding of ISAM includes 87 papers which have been divided in to ten different sections. These include production and processing, coating and thin films, characterization, superconductors and semiconductors mechanical modeling, mechanical testing and life prediction composites, corrosion and oxidation, single crystals and related papers. Ten eminent researchers and scholars of international fame presented their keynote/invited lectures of 40 minutes each. This symposium provided an ideal opportunity for exchange of information amongst scientists, engineers, and researchers from all over Pakistan and 30 other countries of the world. (A.B.)

  11. Advances in Computers

    CERN Document Server

    Zelkowitz, Marvin

    2010-01-01

    This is volume 79 of Advances in Computers. This series, which began publication in 1960, is the oldest continuously published anthology that chronicles the ever- changing information technology field. In these volumes we publish from 5 to 7 chapters, three times per year, that cover the latest changes to the design, development, use and implications of computer technology on society today. Covers the full breadth of innovations in hardware, software, theory, design, and applications.Many of the in-depth reviews have become standard references that co

  12. Advances in Solidification Processing

    Directory of Open Access Journals (Sweden)

    Hugo F. Lopez

    2015-08-01

    Full Text Available Melt solidification is the shortest and most viable route to obtain components, starting from the design to the finished products. Hence, a sound knowledge of the solidification of metallic materials is essential for the development of advanced structural metallic components that drive modern technological societies. As a result, there have been innumerable efforts and full conferences dedicated to this important subject [1–6]. In addition, there are various scientific journals fully devoted to investigating the various aspects which give rise to various solidification microstructures [7–9]. [...

  13. Advanced air distribution

    DEFF Research Database (Denmark)

    Melikov, Arsen Krikor

    2011-01-01

    The aim of total volume air distribution (TVAD) involves achieving uniform temperature and velocity in the occupied zone and environment designed for an average occupant. The supply of large amounts of clean and cool air are needed to maintain temperature and pollution concentration at acceptable....... Ventilation in hospitals is essential to decrease the risk of airborne cross-infection. At present, mixing air distribution at a minimum of 12 ach is used in infection wards. Advanced air distribution has the potential to aid in achieving healthy, comfortable and productive indoor environments at levels...... higher than what can be achieved today with the commonly used total volume air distribution principles....

  14. Advances in quantum electronics

    CERN Document Server

    Goodwin, D W

    1974-01-01

    Advances in Quantum Electronics, Volume 2 deals with the effects of quantum mechanics on the behavior of electrons in matter. This book is divided into three chapters. Chapter 1 reviews the statistical properties of optical fields and spectral processing techniques, including the use of photon correlation techniques to measure scattering effects in a number of different media. The use of optical E.P.R. and excitation spectroscopic techniques and techniques for establishing the location of impurity ions in the chalcogenides are describe in Chapter 2. The last chapter surveys the field of mode l

  15. Advances in Modal Logic

    DEFF Research Database (Denmark)

    Modal logic is a subject with ancient roots in the western logical tradition. Up until the last few generations, it was pursued mainly as a branch of philosophy. But in recent years, the subject has taken new directions with connections to topics in computer science and mathematics. This volume is...... the proceedings of the conference of record in its fi eld, Advances in Modal Logic. Its contributions are state-of-the-art papers. The topics include decidability and complexity results for specifi c modal logics, proof theory of modal logic, logics for reasoning about time and space, provability...

  16. Advanced formal verification

    CERN Document Server

    Drechsler, Rolf

    2007-01-01

    Preface. Contributing Authors. Introduction; R. Drechsler. 1. Formal Verification. 2. Challenges. 3. Contributions to this Book. 1: What SAT-Solvers Can and Cannot Do; E. Goldberg. 1. Introduction. 2. Hard Equivalence Checking CNF Formulas. 3. Stable Sets of Points. 2: Advancements in Mixed BDD and SAT Techniques; G. Cabodi, S. Quer. 1. Introduction. 2. Background. 3. Comparing SAT and BDD Approaches: Are they Different? 4. Decision Diagrams as a Slave Engine in General SAT: Clause Compression by Means of ZBDDs. 5. Decision Diagram Preprocessing and Circuit-Based SAT. 6. Using SAT in Symbolic

  17. Advances in computers

    CERN Document Server

    Memon, Atif

    2012-01-01

    Since its first volume in 1960, Advances in Computers has presented detailed coverage of innovations in computer hardware, software, theory, design, and applications. It has also provided contributors with a medium in which they can explore their subjects in greater depth and breadth than journal articles usually allow. As a result, many articles have become standard references that continue to be of sugnificant, lasting value in this rapidly expanding field. In-depth surveys and tutorials on new computer technologyWell-known authors and researchers in the fieldExtensive bibliographies with m

  18. Advances in biomedical engineering

    CERN Document Server

    Brown, J H U

    1973-01-01

    Advances in Biomedical Engineering, Volume 2, is a collection of papers that discusses the basic sciences, the applied sciences of engineering, the medical sciences, and the delivery of health services. One paper discusses the models of adrenal cortical control, including the secretion and metabolism of cortisol (the controlled process), as well as the initiation and modulation of secretion of ACTH (the controller). Another paper discusses hospital computer systems-application problems, objective evaluation of technology, and multiple pathways for future hospital computer applications. The pos

  19. Advanced calculus problem solver

    CERN Document Server

    REA, Editors of

    2012-01-01

    Each Problem Solver is an insightful and essential study and solution guide chock-full of clear, concise problem-solving gems. All your questions can be found in one convenient source from one of the most trusted names in reference solution guides. More useful, more practical, and more informative, these study aids are the best review books and textbook companions available. Nothing remotely as comprehensive or as helpful exists in their subject anywhere. Perfect for undergraduate and graduate studies.Here in this highly useful reference is the finest overview of advanced calculus currently av

  20. THE ADVANCED STELLAR COMPASS

    DEFF Research Database (Denmark)

    Jørgensen, John Leif; Liebe, Carl Christian

    The science objective of the Danish Geomagnetic Research Satellite "Ørsted" is to map the magnetic field of the Earth, with a vector precision of a fraction of a nanotesla. This necessitates an attitude reference instrument with a precision of a few arcseconds onboard the satellite. To meet this...... demand the Advanced Stellar Compass (ASC), a fully autonomous miniature star tracker, was developed. This ASC is capable of both solving the "lost in space" problem and determine the attitude with arcseconds precision. The development, principles of operation and instrument autonomy of the ASC is...

  1. Advanced thermal management materials

    CERN Document Server

    Jiang, Guosheng; Kuang, Ken

    2012-01-01

    ""Advanced Thermal Management Materials"" provides a comprehensive and hands-on treatise on the importance of thermal packaging in high performance systems. These systems, ranging from active electronically-scanned radar arrays to web servers, require components that can dissipate heat efficiently. This requires materials capable of dissipating heat and maintaining compatibility with the packaging and dye. Its coverage includes all aspects of thermal management materials, both traditional and non-traditional, with an emphasis on metal based materials. An in-depth discussion of properties and m

  2. Advanced structural wind engineering

    CERN Document Server

    Kareem, Ahsan

    2013-01-01

    This book serves as a textbook for advanced courses as it introduces state-of-the-art information and the latest research results on diverse problems in the structural wind engineering field. The topics include wind climates, design wind speed estimation, bluff body aerodynamics and applications, wind-induced building responses, wind, gust factor approach, wind loads on components and cladding, debris impacts, wind loading codes and standards, computational tools and computational fluid dynamics techniques, habitability to building vibrations, damping in buildings, and suppression of wind-induced vibrations. Graduate students and expert engineers will find the book especially interesting and relevant to their research and work.

  3. Advances in biomedical engineering

    CERN Document Server

    Brown, J H U

    1974-01-01

    Advances in Biomedical Engineering, Volume 4, is a collection of papers that deals with gas chromatography, mass spectroscopy and the analysis of minute samples, as well as the role of the government in regulating the production, usage, safety, and efficacy of medical devices. One paper reviews the use of mass spectrometry and computer technology in relation to gas-phase analytical methods based on gas chromatograph-mass spectrometer instruments and gas chromatograph-mass spectrometer-computer analytical systems. Many health practitioners, government and private health agencies, the legal prof

  4. Advances in microwaves 4

    CERN Document Server

    Young, Leo

    2013-01-01

    Advances in Microwaves, Volume 4 covers some innovations in the devices and applications of microwaves. This volume contains three chapters and begins with a discussion of the application of microwave phasers and time delay elements as beam steering elements in array radars. The next chapter provides first an overview of the technical aspects and different types of millimeter waveguides, followed by a survey of their application to railroads. The last chapter examines the general mode of conversion properties of nonuniform waveguides, such as waveguide tapers, using converted Maxwell's equatio

  5. Advanced Remediation Technologies

    International Nuclear Information System (INIS)

    The United States Department of Energy (DOE), Office of Environmental Management (EM) is responsible for the cleanup of nation's nuclear weapons program legacy wastes, along with waste associated with nuclear energy programs and research. The EM cleanup efforts continue to progress, however the cleanup continues to be technologically complex, heavily regulated, long-term; and the effort also has a high life cycle cost estimate (LCCE) effort. Over the past few years, the EM program has undergone several changes to accelerate its cleanup efforts with varying degrees of success. This article will provide some insight into the Advanced Remediation Technologies (ART) projects that may enhance cleanup efforts and reduce life cycle costs. (authors)

  6. Advanced Control Engineering

    DEFF Research Database (Denmark)

    Zhou, Jianjun

    1999-01-01

    This book is developed as a textbook for the course Advanced Control Engineering. The book is intended for students in mechanical engineering and its aim is to provide an understanding of modern control theory as well as methodologies and applications for state space modeling and design. For this...... reason, the book puts emphasis on the state-space approach. The main contents of the book includes state-space representation of dynamic systems, analysis of linear control systems, feedback control and observer design. Both continuous-time and discrete-time systems have been addressed in this book....

  7. Advanced Virgo phase cameras

    Science.gov (United States)

    van der Schaaf, L.; Agatsuma, K.; van Beuzekom, M.; Gebyehu, M.; van den Brand, J.

    2016-05-01

    A century after the prediction of gravitational waves, detectors have reached the sensitivity needed to proof their existence. One of them, the Virgo interferometer in Pisa, is presently being upgraded to Advanced Virgo (AdV) and will come into operation in 2016. The power stored in the interferometer arms raises from 20 to 700 kW. This increase is expected to introduce higher order modes in the beam, which could reduce the circulating power in the interferometer, limiting the sensitivity of the instrument. To suppress these higher-order modes, the core optics of Advanced Virgo is equipped with a thermal compensation system. Phase cameras, monitoring the real-time status of the beam constitute a critical component of this compensation system. These cameras measure the phases and amplitudes of the laser-light fields at the frequencies selected to control the interferometer. The measurement combines heterodyne detection with a scan of the wave front over a photodetector with pin-hole aperture. Three cameras observe the phase front of these laser sidebands. Two of them monitor the in-and output of the interferometer arms and the third one is used in the control of the aberrations introduced by the power recycling cavity. In this paper the working principle of the phase cameras is explained and some characteristic parameters are described.

  8. Microbiological Advances in Biohydrometallurgy

    Directory of Open Access Journals (Sweden)

    Helen Watling

    2016-05-01

    Full Text Available The most exciting advances in biohydrometallurgy are occurring in the field of microbiology. The two main technologies employed in biohydrometallurgy, agitated tanks for the processing of refractory concentrates and heaps and dumps for the processing of low-grade ores, are technologically sound and widely practised at commercial scale, but their development began at a time when very little was known of the microorganisms that assisted metals extraction from sulfide ores. During and subsequent to those developments it has been shown that microbial communities in metals extraction are more diverse than originally thought, and extremely robust and adaptable to different and variable environments. Recent advances in genomics and proteomics, exploiting hugely increased computing power and speed, have made it possible to describe not only which microorganisms are present in bioleaching systems, but also what physiological functions are being exercised. The body of knowledge being acquired through the application of molecular biology methods will be used increasingly to monitor microbial behaviour, optimise conditions for more appropriate microbiological activity and/or infer the “microbiological health” of bioreactors (tanks and heaps.

  9. Recent advances in radiopharmaceuticals

    International Nuclear Information System (INIS)

    Full text: Radiopharmaceuticals in Nuclear Medicine may be divided into diagnostic and therapeutic agents. The diagnostic area is perceived to be mature, while the therapeutic side of nuclear medicine is still evolving. There are over 100 diagnostic radiopharmaceutical products available, the greatest number applied in cardiology followed by oncology and neurology. The greatest success in therapeutic nuclear medicine has been achieved in thyroid cancer, hyperthyroidism and bone pain palliation. Those in the field believe the future of nuclear medicine resides in the growth potential of the emerging therapeutic market, hence much of the recent research has been focussed in the development of therapeutic agents for targeting cancers. Radiopharmaceuticals under development or in clinical trials involve the use of radionuclides such as Y-90, Pd-103, Ir-192, Re-188, I-131, Sm-153, Sn-114, Sr-90, Cu-64 and In-111. Advances in cyclotron and camera technology as well as automation has enhanced and widened the potential use of positron emitting radiopharmaceuticals such as F-18 Fluorodeoxyglucose (FDG). However the relationship between FDG uptake and glucose consumption in normal and diseased tissue is still to be defined. Many challenges remain for the nuclear medicine community to apply new knowledge of human biochemistry in the development of new radiopharmaceuticals. A better understanding of effects of radiation and its role in the design of therapeutic agents is undoubtedly pivotal for advancing therapeutic Nuclear Medicine into the future

  10. Advanced Liquid Feed Experiment

    Science.gov (United States)

    Distefano, E.; Noll, C.

    1993-06-01

    The Advanced Liquid Feed Experiment (ALFE) is a Hitchhiker experiment flown on board the Shuttle of STS-39 as part of the Space Test Payload-1 (STP-1). The purpose of ALFE is to evaluate new propellant management components and operations under the low gravity flight environment of the Space Shuttle for eventual use in an advanced spacecraft feed system. These components and operations include an electronic pressure regulator, an ultrasonic flowmeter, an ultrasonic point sensor gage, and on-orbit refill of an auxiliary propellant tank. The tests are performed with two transparent tanks with dyed Freon 113, observed by a camera and controlled by ground commands and an on-board computer. Results show that the electronic pressure regulator provides smooth pressure ramp-up, sustained pressure control, and the flexibility to change pressure settings in flight. The ultrasonic flowmeter accurately measures flow and detects gas ingestion. The ultrasonic point sensors function well in space, but not as a gage during sustained low-gravity conditions, as they, like other point gages, are subject to the uncertainties of propellant geometry in a given tank. Propellant transfer operations can be performed with liquid-free ullage equalization at a 20 percent fill level, gas-free liquid transfer from 20-65 percent fill level, minimal slosh, and can be automated.

  11. Advances in speech processing

    Science.gov (United States)

    Ince, A. Nejat

    1992-10-01

    The field of speech processing is undergoing a rapid growth in terms of both performance and applications and this is fueled by the advances being made in the areas of microelectronics, computation, and algorithm design. The use of voice for civil and military communications is discussed considering advantages and disadvantages including the effects of environmental factors such as acoustic and electrical noise and interference and propagation. The structure of the existing NATO communications network and the evolving Integrated Services Digital Network (ISDN) concept are briefly reviewed to show how they meet the present and future requirements. The paper then deals with the fundamental subject of speech coding and compression. Recent advances in techniques and algorithms for speech coding now permit high quality voice reproduction at remarkably low bit rates. The subject of speech synthesis is next treated where the principle objective is to produce natural quality synthetic speech from unrestricted text input. Speech recognition where the ultimate objective is to produce a machine which would understand conversational speech with unrestricted vocabulary, from essentially any talker, is discussed. Algorithms for speech recognition can be characterized broadly as pattern recognition approaches and acoustic phonetic approaches. To date, the greatest degree of success in speech recognition has been obtained using pattern recognition paradigms. It is for this reason that the paper is concerned primarily with this technique.

  12. ADVANCED TURBINE SYSTEMS PROGRAM

    Energy Technology Data Exchange (ETDEWEB)

    Gregory Gaul

    2004-04-21

    Natural gas combustion turbines are rapidly becoming the primary technology of choice for generating electricity. At least half of the new generating capacity added in the US over the next twenty years will be combustion turbine systems. The Department of Energy has cosponsored with Siemens Westinghouse, a program to maintain the technology lead in gas turbine systems. The very ambitious eight year program was designed to demonstrate a highly efficient and commercially acceptable power plant, with the ability to fire a wide range of fuels. The main goal of the Advanced Turbine Systems (ATS) Program was to develop ultra-high efficiency, environmentally superior and cost effective competitive gas turbine systems for base load application in utility, independent power producer and industrial markets. Performance targets were focused on natural gas as a fuel and included: System efficiency that exceeds 60% (lower heating value basis); Less than 10 ppmv NO{sub x} emissions without the use of post combustion controls; Busbar electricity that are less than 10% of state of the art systems; Reliability-Availability-Maintainability (RAM) equivalent to current systems; Water consumption minimized to levels consistent with cost and efficiency goals; and Commercial systems by the year 2000. In a parallel effort, the program was to focus on adapting the ATS engine to coal-derived or biomass fuels. In Phase 1 of the ATS Program, preliminary investigators on different gas turbine cycles demonstrated that net plant LHV based efficiency greater than 60% was achievable. In Phase 2 the more promising cycles were evaluated in greater detail and the closed-loop steam-cooled combined cycle was selected for development because it offered the best solution with least risk for achieving the ATS Program goals for plant efficiency, emissions, cost of electricity and RAM. Phase 2 also involved conceptual ATS engine and plant design and technology developments in aerodynamics, sealing

  13. Advances in solar sailing

    CERN Document Server

    Third International Symposium on Solar Sailing

    2014-01-01

    Hosted by the Advanced Space Concepts Laboratory within the department of Mechanical and Aerospace Engineering of the University of Strathclyde, the third International Symposium on Solar Sailing was held in McCance Building at 16 Richmond Street, Glasgow, between 11 and 13 June 2013. The symposium attracted over 90 delegates from19 different counties, bringing together international experts from across the globe to discuss funded solar sail flight programs alongside on-going technology development and testing programs. The symposium also provided a forum for the discussion of enabling technologies, new application concepts, materials and structural concepts, space environmental effects, dynamics, navigation, control, and much more. This volume contains the unabridged symposium proceedings, in the gathered experts own words. As symposium chair, I thank our partners at Scottish Enterprise and L’Garde, Inc., the symposium’s gold sponsor, for their support in realising this symposium.

  14. Advances in autism.

    Science.gov (United States)

    Geschwind, Daniel H

    2009-01-01

    Autism is a common childhood neurodevelopmental disorder with strong genetic liability. It is not a unitary entity but a clinical syndrome, with variable deficits in social behavior and language, restrictive interests, and repetitive behaviors. Recent advances in the genetics of autism emphasize its etiological heterogeneity, with each genetic susceptibility locus accounting for only a small fraction of cases or having a small effect. Therefore, it is not surprising that no unifying structural or neuropathological features have been conclusively identified. Given the heterogeneity of autism spectrum disorder (ASD), approaches based on studying heritable components of the disorder, or endophenotypes, such as language or social cognition, provide promising avenues for genetic and neurobiological investigations. Early intensive behavioral and cognitive interventions are efficacious in many cases, but autism does not remit in the majority of children. Therefore, development of targeted therapies based on pathophysiologically and etiologically defined subtypes of ASD remains an important and achievable goal of current research. PMID:19630577

  15. Biotechnological advances in Lilium.

    Science.gov (United States)

    Bakhshaie, Mehdi; Khosravi, Solmaz; Azadi, Pejman; Bagheri, Hedayat; van Tuyl, Jaap M

    2016-09-01

    Modern powerful techniques in plant biotechnology have been developed in lilies (Lilium spp., Liliaceae) to propagate, improve and make new phenotypes. Reliable in vitro culture methods are available to multiply lilies rapidly and shorten breeding programs. Lilium is also an ideal model plant to study in vitro pollination and embryo rescue methods. Although lilies are recalcitrant to genetic manipulation, superior genotypes are developed with improved flower colour and form, disease resistance and year round forcing ability. Different DNA molecular markers have been developed for rapid indirect selection, genetic diversity evaluation, mutation detection and construction of Lilium linkage map. Some disease resistance-QTLs are already mapped on the Lilium linkage map. This review presents latest information on in vitro propagation, genetic engineering and molecular advances made in lily. PMID:27318470

  16. Buildings for advanced technology

    CERN Document Server

    Teague, E; Murday, James

    2015-01-01

    This book deals with the design and construction of buildings for nanoscale science and engineering research. The information provided in this book is useful for designing and constructing buildings for such advanced technologies as nanotechnology, nanoelectronics and biotechnology. The book outlines the technology challenges unique to each of the building environmental challenges outlined below and provides best practices and examples of engineering approaches to address them: • Establishing and maintaining critical environments: temperature, humidity, and pressure • Structural vibration isolation • Airborne vibration isolation (acoustic noise) • Isolation of mechanical equipment-generated vibration/acoustic noise • Cost-effective power conditioning • Grounding facilities for low electrical interference • Electromagnetic interference (EMI)/Radio frequency interference (RFI) isolation • Airborne particulate contamination • Airborne organic and chemical contamination • Environment, safety a...

  17. Advances in PV Inverters

    DEFF Research Database (Denmark)

    Anthon, Alexander

    operation mode is thoroughly described identifying its limitations for high efficiency operation. With these results, the first approach utilizes low loss switching devices and their influence on the semiconductor loss behavior is analyzed. The results show that, for near unity power factor operation...... and new approaches are necessary. Therefore, research areas typically focus on both new topologies and utilizing more advanced semiconductor devices. To this end, semiconductor devices made of Silicon Carbide have been gaining increasing interest in the last two decades after the successful...... commercialization of high voltage power diodes. By now, the performance potential of switching devices made of Silicon Carbide is commonly accepted, though they have not found commonplace usage within commercial converter systems for several reasons, among others reliability, availability/cost and gate driver...

  18. Advances in analytical chemistry

    Science.gov (United States)

    Arendale, W. F.; Congo, Richard T.; Nielsen, Bruce J.

    1991-01-01

    Implementation of computer programs based on multivariate statistical algorithms makes possible obtaining reliable information from long data vectors that contain large amounts of extraneous information, for example, noise and/or analytes that we do not wish to control. Three examples are described. Each of these applications requires the use of techniques characteristic of modern analytical chemistry. The first example, using a quantitative or analytical model, describes the determination of the acid dissociation constant for 2,2'-pyridyl thiophene using archived data. The second example describes an investigation to determine the active biocidal species of iodine in aqueous solutions. The third example is taken from a research program directed toward advanced fiber-optic chemical sensors. The second and third examples require heuristic or empirical models.

  19. The advanced photon source

    International Nuclear Information System (INIS)

    The Advanced Photon Source (APS) is a 7-GeV third-generation synchrotron radiation storage ring and full-energy positron injector. Construction project funding began in 1989, and ground breaking took place on 5 May 1990. Construction of all accelerator facilities was completed in January 1995 and storage ring commissioning is underway. First observation of x-rays from a bending magnet source took place on 26 March 1995. Nearly all performance specifications of the injector have been reached, and first observations indicate that the reliability, dynamic aperture, emittance, and orbit stability in the storage ring are satisfactory. Observation of radiation from the first of 20 insertion device beamlines is scheduled for October 1995. Start of regular operations is expected to take place well before the APS Project target date of December 1996

  20. Advanced drilling systems study.

    Energy Technology Data Exchange (ETDEWEB)

    Pierce, Kenneth G.; Livesay, Billy Joe; Finger, John Travis (Livesay Consultants, Encintas, CA)

    1996-05-01

    This report documents the results of a study of advanced drilling concepts conducted jointly for the Natural Gas Technology Branch and the Geothermal Division of the U.S. Department of Energy. A number of alternative rock cutting concepts and drilling systems are examined. The systems cover the range from current technology, through ongoing efforts in drilling research, to highly speculative concepts. Cutting mechanisms that induce stress mechanically, hydraulically, and thermally are included. All functions necessary to drill and case a well are considered. Capital and operating costs are estimated and performance requirements, based on comparisons of the costs for alternative systems to conventional drilling technology, are developed. A number of problems common to several alternatives and to current technology are identified and discussed.

  1. Advanced powder processing

    Energy Technology Data Exchange (ETDEWEB)

    Janney, M.A. [Oak Ridge National Lab., TN (United States)

    1997-04-01

    Gelcasting is an advanced powder forming process. It is most commonly used to form ceramic or metal powders into complex, near-net shapes. Turbine rotors, gears, nozzles, and crucibles have been successfully gelcast in silicon nitride, alumina, nickel-based superalloy, and several steels. Gelcasting can also be used to make blanks that can be green machined to near-net shape and then high fired. Green machining has been successfully applied to both ceramic and metal gelcast blanks. Recently, the authors have used gelcasting to make tooling for metal casting applications. Most of the work has centered on H13 tool steel. They have demonstrated an ability to gelcast and sinter H13 to near net shape for metal casting tooling. Also, blanks of H13 have been cast, green machined into complex shape, and fired. Issues associated with forming, binder burnout, and sintering are addressed.

  2. Advances in DUV spectroscopy

    DEFF Research Database (Denmark)

    Buchhave, Preben; Tidemand-Lichtenberg, Peter; Mogensen, Claus Tilsted

    The would-be advantages of deep UV (DUV) spectroscopy are well known, but the potential applications have so far not been fully realized due to technological limitations and, perhaps, lack of bright ideas. However, new components and new knowledge about DUV spectra and spectroscopic methods...... combined with increasing needs for solutions to practical problems in environmental protection, medicine and pollution monitoring promise a new era in DUV spectroscopy. Here we shall review the basis for DUV spectroscopy, both DUV fluorescence and DUV Raman spectroscopy, and describe recent advances in...... technology and principles that could be applied to new and improved applications of this promising technique. As an example we describe a recent cooperation between Grundfos, DTU and Intarsia Optics to measure live bacterial cells in drinking water....

  3. Advances in integrated optics

    CERN Document Server

    Chester, A; Bertolotti, M

    1994-01-01

    This volwne contains the Proceedings of a two-week summer conference titled "Advances in Integrated Optics" held June 1-9, 1993, in Erice, Sicily. This was the 18th annual course organized by the International School of Quantum Electronics, under the auspices of the "Ettore Majorana" Centre for Scientific Culture. The term Integrated Optics signifies guided-wave optical circuits consisting of two or more devices on a single substrate. Since its inception in the late 1960's, Integrated Optics has evolved from a specialized research topic into a broad field of work, ranging from basic research through commercial applications. Today many devices are available on market while a big effort is devolved to research on integrated nonlinear optical devices. This conference was organized to provide a comprehensive survey of the frontiers of this technology, including fundamental concepts, nonlinear optical materials, devices both in the linear and nonlinear regimes, and selected applications. These Proceedings update a...

  4. Advances in Nanoimprint Lithography.

    Science.gov (United States)

    Traub, Matthew C; Longsine, Whitney; Truskett, Van N

    2016-06-01

    Nanoimprint lithography (NIL), a molding process, can replicate features fundamental principles underlying the two most commonly used types of NIL, thermal and UV, and contrast them with conventional photolithography methods used in the semiconductor industry. We then describe current advances toward full commercial industrialization of UV-curable NIL (UV-NIL) technology for integrated circuit production. We conclude with brief overviews of some emerging areas of research, from photonics to biotechnology, in which the ability of NIL to fabricate structures of arbitrary geometry is providing new paths for development. As with previous innovations, the increasing availability of tools and techniques from the semiconductor industry is poised to provide a path to bring these innovations from the lab to everyday life. PMID:27070763

  5. Advances in atomic spectroscopy

    CERN Document Server

    Sneddon, J

    2000-01-01

    This fifth volume of the successful series Advances in Atomic Spectroscopy continues to discuss and investigate the area of atomic spectroscopy.It begins with a description of the use of various atomic spectroscopic methods and applications of speciation studies in atomic spectroscopy. The emphasis is on combining atomic spectroscopy with gas and liquid chromatography. In chapter two the authors describe new developments in tunable lasers and the impact they will have on atomic spectroscopy. The traditional methods of detection, such as photography and the photomultiplier, and how they are being replaced by new detectors is discussed in chapter three. The very active area of glow discharge atomic spectrometry is presented in chapter four where, after a brief introduction and historical review, the use of glow discharge lamps for atomic spectroscopy and mass spectrometry are discussed. Included in this discussion is geometry and radiofrequency power. The future of this source in atomic spectroscopy is also dis...

  6. Advanced differential quadrature methods

    CERN Document Server

    Zong, Zhi

    2009-01-01

    Modern Tools to Perform Numerical DifferentiationThe original direct differential quadrature (DQ) method has been known to fail for problems with strong nonlinearity and material discontinuity as well as for problems involving singularity, irregularity, and multiple scales. But now researchers in applied mathematics, computational mechanics, and engineering have developed a range of innovative DQ-based methods to overcome these shortcomings. Advanced Differential Quadrature Methods explores new DQ methods and uses these methods to solve problems beyond the capabilities of the direct DQ method.After a basic introduction to the direct DQ method, the book presents a number of DQ methods, including complex DQ, triangular DQ, multi-scale DQ, variable order DQ, multi-domain DQ, and localized DQ. It also provides a mathematical compendium that summarizes Gauss elimination, the Runge-Kutta method, complex analysis, and more. The final chapter contains three codes written in the FORTRAN language, enabling readers to q...

  7. Recent advances in VECSELs

    Science.gov (United States)

    Rahimi-Iman, Arash

    2016-09-01

    Within the last two decades, vertical-external-cavity surface-emitting lasers (VECSELs) have attracted rising interest from both industry and science. They have proven to be versatile lasers which can be specifically designed for research and applications that require a particular regime of operation. Various emission schemes ranging from narrow-linewidth emission, pulsed light or multimode emission to a frequency-converted output are feasible owing to remarkable device features. Being composed of a semiconductor gain mirror and an external cavity, not only is a unique access to high-brightness output and a high-beam quality is provided, but also wavelength flexibility. Moreover, the exploitation of intra-cavity frequency conversion further extends the accessible spectral range from the ultraviolet (UV) to the terahertz (THz). In this work, recent advances in the field of VECSELs are highlighted.

  8. Dietary advanced glycation endproducts

    DEFF Research Database (Denmark)

    Poulsen, Malene Wibe

    High heat cooking induces flavor, aroma, and color of food, but leads to formation of advanced glycation endproducts (AGEs) by the Maillard reaction. In addition to the formation in food, AGEs are also formed in vivo, and increased endogenous formation of AGEs has been linked to diabetic...... postprandial subjective appetite sensations, appetite hormones, and markers of inflammation of two cooking methods that respectively induce or limit AGE formation were investigated in healthy overweight individuals. It was concluded that the meals affected subjective appetite sensations similarly, but the high...... sensitivity of cooking methods that induce or limit AGE formation were investigated in healthy overweight women. It was concluded that insulin sensitivity was improved with use of low heat cooking methods, compared with high heat cooking methods. In a rat study, effects on expression of AGE receptors, insulin...

  9. Advanced Visual Quantum Mechanics

    CERN Document Server

    Thaller, Bernd

    2005-01-01

    Advanced Visual Quantum Mechanics is a systematic effort to investigate and to teach quantum mechanics with the aid of computer-generated animations. It is a self-contained textbook that combines selected topics from atomic physics (spherical symmetry, the hydrogen atom, and particles with spin) with an introduction to quantum information theory (qubits, EPR paradox, teleportation, quantum computers). It explores relativistic quantum mechanics and the strange behavior of Dirac equation solutions. A series of appendices covers important topics from perturbation and scattering theory. The book places an emphasis on ideas and concepts, with a fair to moderate amount of mathematical rigor. Though this book stands alone, it can also be paired with Thaller Visual Quantum Mechanics to form a comprehensive course in quantum mechanics. The software for the first book earned the European Academic Software Award 2000 for outstanding innovation in its field.

  10. Advanced finite element technologies

    CERN Document Server

    Wriggers, Peter

    2016-01-01

    The book presents an overview of the state of research of advanced finite element technologies. Besides the mathematical analysis, the finite element development and their engineering applications are shown to the reader. The authors give a survey of the methods and technologies concerning efficiency, robustness and performance aspects. The book covers the topics of mathematical foundations for variational approaches and the mathematical understanding of the analytical requirements of modern finite element methods. Special attention is paid to finite deformations, adaptive strategies, incompressible, isotropic or anisotropic material behavior and the mathematical and numerical treatment of the well-known locking phenomenon. Beyond that new results for the introduced approaches are presented especially for challenging nonlinear problems.

  11. The Advanced Light Source

    International Nuclear Information System (INIS)

    The Advanced Light Source (ALS), a national user facility currently under construction at the Lawrence Berkeley Laboratory (LBL), is a third-generation synchrotron light source designed to produce extremely bright beams of synchrotron radiation in the energy range from a few eV to 10 keV. The design is based on a 1--1.9-GeV electron storage ring (optimized at 1.5 GeV), and utilizes special magnets, known as undulators and wigglers (collectively referred to as insertion devices), to generate the radiation. The facility is scheduled to begin operating in April 1993. In this paper we describe the progress in the design, construction, and commissioning of the accelerator systems, insertion devices, and beamlines. Companion presentations at this conference give more detail of specific components in the ALS, and describe the activities towards establishing an exciting user program. 3 figs., 2 tabs

  12. USMC UGS technology advancements

    Science.gov (United States)

    Hartup, David C.; Barr, Michael E.; Hirz, Philip M.; Kipp, Jason; Fishburn, Thomas A.; Waller, Ezra S.; Marks, Brian A.

    2008-04-01

    Technology advancements for the USMC UGS system are described. Integration of the ARL Blue Radio/CSR into the System Controller and Radio Repeater permit the TRSS system to operate seamlessly within the Family of UGS concept. In addition to the Blue Radio/CSR, the TRSS system provides VHF and SATCOM radio links. The TRSS system is compatible with a wide range of imagers, including those with both analog and digital interfaces. The TRSS System Controller permits simultaneous monitoring of 2 camera inputs. To complement enhanced compatibility and improved processing, the mechanical housing of the TRSS System Controller has been updated. The SDR-II, a system monitoring device, also incorporates four Blue Radio/CSRs along with other communication capabilities, making it an ideal choice for a monitoring station within the Family of UGS. Field testing of L-3 Nova's UGS system at YPG has shown flawless performance, capturing all 126 targets.

  13. Advanced biomaterials and biodevices

    CERN Document Server

    Tiwari, Ashutosh

    2014-01-01

    Biomaterials are the fastest-growing emerging field of  biodevices. Design and development of biomaterials play a significant role in the diagnosis, treatment, and prevention of diseases. Recently, a variety of scaffolds/carriers have been evaluated for tissue regeneration, drug delivery, sensing and imaging.  Liposomes and microspheres have been developed for sustained delivery. Several anti-cancer drugs have been successfully formulated using biomaterial. The targeting of drugs to certain physiological sites has emerged as a promising tool in the treatment with improved drug bioavailability and reduction of dosing frequency. Biodevices-based targeting of drugs may improve the therapeutic success by limiting the adverse drug effects and resulting in more patient compliance and attaining a higher adherence level. Advanced biodevices hold merit as a drug carrier with high carrier capacity, feasibility of incorporation of both hydrophilic and hydrophobic substances, high stability, as well as the feasibility...

  14. [Advanced pulmonary alveolar microlithiasis].

    Science.gov (United States)

    Triebel, H J; von Hülst, M; Schofer, M

    1987-09-01

    A severe course of microlithiasis alveolaris pulmonum in a 28-year old patient is described. The disease, which had progressed to a very advanced stage at the time of examination, produced in the plain radiograph of the thorax an extensive, homogeneous, ground-glass like shadow of practically all organs of the thorax. The typical miliary (spot-like) shadow ("sandstorm lung") is visible only in the lateral and apical parts of the lung. CT revealed massive calcareous deposits which increased in craniocaudal and ventrodorsal direction. Bullous metaplasia of the lung was particularly striking in the apical region. No effective therapy is known so far. A combined heart and lung transplantation might be the only therapy that could prolong the patient's life. PMID:3659783

  15. Advanced microlithiasis alveolaris pulmonum

    Energy Technology Data Exchange (ETDEWEB)

    Triebel, H.J.; Schofer, M.; Huelst, M. v.

    1987-09-01

    A severe course of microlithiasis alveolaris pulmonum in a 28-year old patient is described. The disease, which had progressed to a very advanced stage at the time of examination, produced in the plain radiograph of the thorax an extensive, homogeneous, ground-glass like shadow of practically all organs of the thorax. The typical miliary (spotlike) shadow ('sandstorm lung') is visible only in the lateral and apical parts of the lung. CT revealed massive calcareous deposits which increased in craniocaudal and ventrodorsal direction. Bullous metaplasia of the lung was particularly striking in the apical region. No effective therapy is known so far. A combined heart and lung transplantation might be the only therapy that could prolong the patient's life.

  16. Polarons in advanced materials

    CERN Document Server

    Alexandrov, Alexandre Sergeevich

    2008-01-01

    Polarons in Advanced Materials will lead the reader from single-polaron problems to multi-polaron systems and finally to a description of many interesting phenomena in high-temperature superconductors, ferromagnetic oxides, conducting polymers and molecular nanowires. The book divides naturally into four parts. Part I introduces a single polaron and describes recent achievements in analytical and numerical studies of polaron properties in different electron-phonon models. Part II and Part III describe multi-polaron physics, and Part IV describes many key physical properties of high-temperature superconductors, colossal magnetoresistance oxides, conducting polymers and molecular nanowires, which were understood with polarons and bipolarons. The book is written in the form of self-consistent reviews authored by well-established researchers actively working in the field and will benefit scientists and postgraduate students with a background in condensed matter physics and materials sciences.

  17. Advanced adhesives in electronics

    CERN Document Server

    Bailey, C

    2011-01-01

    Adhesives are widely used in the manufacture of electronic devices to act as passive and active components. Recently there has been considerable interest in the use of conductive adhesives. This book reviews key types of conductive adhesives, processing methods, properties and the way they can be modelled as well as potential applications.$bAdhesives for electronic applications serve important functional and structural purposes in electronic components and packaging, and have developed significantly over the last few decades. Advanced adhesives in electronics reviews recent developments in adhesive joining technology, processing and properties. The book opens with an introduction to adhesive joining technology for electronics. Part one goes on to cover different types of adhesive used in electronic systems, including thermally conductive adhesives, isotropic and anisotropic conductive adhesives and underfill adhesives for flip-chip applications. Part two focuses on the properties and processing of electronic ...

  18. Advanced engineering mathematics

    CERN Document Server

    Jeffrey, Alan

    2001-01-01

    Advanced Engineering Mathematics provides comprehensive and contemporary coverage of key mathematical ideas, techniques, and their widespread applications, for students majoring in engineering, computer science, mathematics and physics. Using a wide range of examples throughout the book, Jeffrey illustrates how to construct simple mathematical models, how to apply mathematical reasoning to select a particular solution from a range of possible alternatives, and how to determine which solution has physical significance. Jeffrey includes material that is not found in works of a similar nature, such as the use of the matrix exponential when solving systems of ordinary differential equations. The text provides many detailed, worked examples following the introduction of each new idea, and large problem sets provide both routine practice, and, in many cases, greater challenge and insight for students. Most chapters end with a set of computer projects that require the use of any CAS (such as Maple or Mathematica) th...

  19. Advanced medical accelerator design

    International Nuclear Information System (INIS)

    This report describes the design of an advanced medical facility dedicated to charged particle radiotherapy and other biomedical applications of relativistic heavy ions. Project status is reviewed and some technical aspects discussed. Clinical standards of reliability are regarded as essential features of this facility. Particular emphasis is therefore placed on the control system and on the use of technology which will maximize operational efficiency. The accelerator will produce a variety of heavy ion beams from helium to argon with intensities sufficient to provide delivered dose rates of several hundred rad/minute over large, uniform fields. The technical components consist of a linac injector with multiple PIG ion sources, a synchrotron and a versatile beam delivery system. An overview is given of both design philosophy and selected accelerator subsystems. Finally, a plan of the facility is described

  20. Advanced glaucoma: Management pearls

    Directory of Open Access Journals (Sweden)

    Girum W Gessesse

    2013-01-01

    Full Text Available A significant proportion of glaucoma patients present late, particularly in the developing world, and unfortunately, in an advanced stage of the disease. They are at imminent danger of losing remaining vision, and may also be afflicted with various socioeconomic and health challenges. The encounter with such a patient is typically characterized by anxiety/fear and sometimes hopelessness from the patient′s perspective. The physician may also feel that they are in a difficult position managing the patient′s disease. When dealing with such cases, we suggest a holistic, individualized approach taking into account the ′biopsychosociospiritual′ (BPSS profile of each patient. The BPSS model takes into account relevant ocular as well as systemic biology (factors such as the mechanism of glaucoma, level of intraocular pressure [IOP], rate of progression, life expectancy, general health, psychological considerations (e.g., fear, depression, socio-economic factors and spiritual/cultural values and beliefs before being able to decide with the patient and their care partner(s what treatment goals should be and how they can best be approached. Treatment for advanced glaucoma can be highly effective, and patients and their care partners should be informed that aggressive IOP lowering to the low teens or even single digits offers the best chance of protecting remaining vision. This can be achieved safely and effectively in most cases with trabeculectomy (including an antimetabolite, and in some cases with medical and/or laser therapy. Vision rehabilitation and psychosocial support should also be considered in order to optimize remaining vision, replace fear with hope as appropriate, and thus improve the overall quality of life.

  1. Advanced materials processing

    International Nuclear Information System (INIS)

    Advanced materials will require improved processing methods due to high melting points, low toughness or ductility values, high reactivity with air or ceramics and typically complex crystal structures with significant anisotropy in flow and/or fracture stress. Materials for structural applications at elevated temperature in critical systems will require processing with a high degree of control. This requires an improved understanding of the relationship between process variables and microstructure to enable control systems to achieve consistently high quality. One avenue to the required level of understanding is computer simulation. Past attempts to do process modeling have been hampered by incomplete data regarding thermophysical or mechanical material behavior. Some of the required data can be calculated. Due to the advances in software and hardware, accuracy and costs are in the realm of acquiring experimental data. Such calculations can, for example, be done at an atomic level to compute lattice energy, fault energies, density of states and charge densities. These can lead to fundamental information about the competition between slip and fracture, anisotropy of bond strength (and therefore cleavage strength), cohesive strength, adhesive strength, elastic modulus, thermal expansion and possibly other quantities which are difficult (and therefore expensive to measure). Some of these quantities can be fed into a process model. It is probable that temperature dependencies can be derived numerically as well. Examples are given of the beginnings of such an approach for Ni3Al and MoSi2. Solidification problems are examples of the state-of-the-art process modeling and adequately demonstrate the need for extensive input data. Such processes can be monitored in terms of interfacial position vs. time, cooling rate and thermal gradient

  2. Advanced isotope separation

    International Nuclear Information System (INIS)

    The Study Group briefly reviewed the technical status of the three Advanced Isotope Separation (AIS) processes. It also reviewed the evaluation work that has been carried out by DOE's Process Evaluation Board (PEB) and the Union Carbide Corporation-Nuclear Division (UCCND). The Study Group briefly reviewed a recent draft assessment made for DOE staff of the nonproliferation implications of the AIS technologies. The staff also very briefly summarized the status of GCEP and Advanced Centrifuge development. The Study Group concluded that: (1) there has not been sufficient progress to provide a firm scientific, technical or economic basis on which to select one of the three competing AIS processes for full-scale engineering development at this time; and (2) however, should budgetary restraints or other factors force such a selection, we believe that the evaluation process that is being carried out by the PEB provides the best basis available for making a decision. The Study Group recommended that: (1) any decisions on AIS processes should include a comparison with gas centrifuge processes, and should not be made independently from the plutonium isotope program; (2) in evaluating the various enrichment processes, all applicable costs (including R and D and sales overhead) and an appropriate discounting approach should be included in order to make comparisons on a private industry basis; (3) if the three AIS programs continue with limited resources, the work should be reoriented to focus only on the most pressing technical problems; and (4) if a decision is made to develop the Atomic Vapor Laser Isotope Separation process, the solid collector option should be pursued in parallel to alleviate the potential program impact of liquid collector thermal control problems

  3. Handbook of Advanced Magnetic Materials

    CERN Document Server

    Liu, Yi; Shindo, Daisuke

    2006-01-01

    From high-capacity, inexpensive hard drives to mag-lev trains, recent achievements in magnetic materials research have made the dreams of a few decades ago reality. The objective of Handbook of Advanced Magnetic Materials is to provide a timely, comprehensive review of recent progress in magnetic materials research. This broad yet detailed reference consists of four volumes: 1.) Nanostructured advanced magnetic materials, 2.) Characterization and simulation of advanced magnetic materials, 3.) Processing of advanced magnetic materials, and 4.) Properties and applications of advanced magnetic materials The first volume documents and explains recent development of nanostructured magnetic materials, emphasizing size effects. The second volume provides a comprehensive review of both experimental methods and simulation techniques for the characterization of magnetic materials. The third volume comprehensively reviews recent developments in the processing and manufacturing of advanced magnetic materials. With the co...

  4. Digital Fourier analysis advanced techniques

    CERN Document Server

    Kido, Ken'iti

    2015-01-01

    This textbook is a thorough, accessible introduction to advanced digital Fourier analysis for advanced undergraduate and graduate students. Assuming knowledge of the Fast Fourier Transform, this book covers advanced topics including the Hilbert transform, cepstrum analysis, and the two-dimensional Fourier transform. Saturated with clear, coherent illustrations, "Digital Fourier Analysis - Advanced Techniques" includes practice problems and thorough Appendices. As a central feature, the book includes interactive applets (available online) that mirror the illustrations. These user-friendly applets animate concepts interactively, allowing the user to experiment with the underlying mathematics. The applet source code in Visual Basic is provided online, enabling advanced students to tweak and change the programs for more sophisticated results. A complete, intuitive guide, "Digital Fourier Analysis - Advanced Techniques" is an essential reference for students in science and engineering.

  5. Advanced action in classical electrodynamics

    OpenAIRE

    Boozer, A. D.

    2008-01-01

    The time evolution of a charged point particle is governed by a second-order integro-differential equation that exhibits advanced effects, in which the particle responds to an external force before the force is applied. In this paper we give a simple physical argument that clarifies the origin and physical meaning of these advanced effects, and we compare ordinary electrodynamics with a toy model of electrodynamics in which advanced effects do not occur.

  6. Advanced Situation Awareness Technologies Project

    Data.gov (United States)

    National Aeronautics and Space Administration — Advanced Situation Awareness Technologies (ASAT) will facilitate exploration of the moon surface, and other planetary bodies. This powerful technology will also...

  7. Advanced intelligence and mechanism approach

    Institute of Scientific and Technical Information of China (English)

    ZHONG Yixin

    2007-01-01

    Advanced intelligence will feature the intelligence research in next 50 years.An understanding of the concept of advanced intelligence as well as its importance will be provided first,and detailed analysis on an approach,the mechanism approach.suitable to the advanced intelligence research will then be flolowed.And the mutual relationship among mechanism approach,traditional approaches existed in artificial intelligence research,and the cognitive informatics will be discussed.It is interesting to discover that mechanism approach is a good one to the Advanced Intelligence research and a tmified form of the existed approaches to artificial intelligence.

  8. Advanced reactor experimental facilities

    International Nuclear Information System (INIS)

    For many years, the NEA has been examining advanced reactor issues and disseminating information of use to regulators, designers and researchers on safety issues and research needed. Following the recommendation of participants at an NEA workshop, a Task Group on Advanced Reactor Experimental Facilities (TAREF) was initiated with the aim of providing an overview of facilities suitable for carrying out the safety research considered necessary for gas-cooled reactors (GCRs) and sodium fast reactors (SFRs), with other reactor systems possibly being considered in a subsequent phase. The TAREF was thus created in 2008 with the following participating countries: Canada, the Czech Republic, Finland, France, Germany, Hungary, Italy, Japan, Korea and the United States. In a second stage, India provided valuable information on its experimental facilities related to SFR safety research. The study method adopted entailed first identifying high-priority safety issues that require research and then categorizing the available facilities in terms of their ability to address the safety issues. For each of the technical areas, the task members agreed on a set of safety issues requiring research and established a ranking with regard to safety relevance (high, medium, low) and the status of knowledge based on the following scale relative to full knowledge: high (100%-75%), medium (75 - 25%) and low (25-0%). Only the issues identified as being of high safety relevance and for which the state of knowledge is low or medium were included in the discussion, as these issues would likely warrant further study. For each of the safety issues, the TAREF members identified appropriate facilities, providing relevant information such as operating conditions (in- or out-of reactor), operating range, description of the test section, type of testing, instrumentation, current status and availability, and uniqueness. Based on the information collected, the task members assessed prospects and priorities

  9. Advanced Concepts. Chapter 21

    Science.gov (United States)

    Johnson, Les; Mulqueen, Jack

    2013-01-01

    Before there is a funded space mission, there must be a present need for the mission. Space science and exploration are expensive, and without a well-defined and justifiable need, no one is going to commit significant funding for any space endeavor. However, as discussed in Chapter 1, applications of space technology and many and broad, hence there are many ways to determine and establish a mission need. Robotic science missions are justified by their science return. To be selected for flight, questions like these must be addressed: What is the science question that needs answering, and will the proposed mission be the most cost-effective way to answer it? Why does answering the question require an expensive space flight, instead of some ground-based alternative? If the question can only be answered by flying in space, then why is this approach better than other potential approaches? How much will it cost? And is the technology required to answer the question in hand and ready to use? If not, then how much will it cost and how long will it take to mature the technology to a usable level? There are also many ways to justify human exploration missions, including science return, technology advancement, as well as intangible reasons, such as national pride. Nonetheless, many of the questions that need answering, are similar to those for robotic science missions: Where are the people going, why, and will the proposed mission be the most cost-effective way to get there? What is the safest method to achieve the goal? How much will it cost? And is the technology required to get there and keep the crew alive in hand and ready to use? If not, then how much will it cost and how long will it take to mature the technology to a usable level? Another reason for some groups sending spacecraft into space is for profit. Telecommunications, geospatial imaging, and tourism are examples of proven, market-driven space missions and applications. For this specific set of users, the

  10. ADVANCED CUTTINGS TRANSPORT STUDY

    Energy Technology Data Exchange (ETDEWEB)

    Troy Reed; Stefan Miska; Nicholas Takach; Kaveh Ashenayi; Mark Pickell; Len Volk; Mike Volk; Evren Ozbayoglu; Lei Zhou

    2002-04-30

    This is the third quarterly progress report for Year 3 of the ACTS Project. It includes a review of progress made in: (1) Flow Loop construction and development and (2) research tasks during the period of time between Jan. 1, 2002 and Mar. 31, 2002. This report presents a review of progress on the following specific tasks: (a) Design and development of an Advanced Cuttings Transport Facility (Task 3: Addition of a Cuttings Injection/Separation System), (b) Research project (Task 6): ''Study of Cuttings Transport with Foam Under LPAT Conditions (Joint Project with TUDRP)'', (c) Research project (Task 9b): ''Study of Foam Flow Behavior Under EPET Conditions'', (d) Research project (Task 10): ''Study of Cuttings Transport with Aerated Mud Under Elevated Pressure and Temperature Conditions'', (e) Research on three instrumentation tasks to measure: Cuttings concentration and distribution in a flowing slurry (Task 11), Foam texture while transporting cuttings. (Task 12), and Viscosity of Foam under EPET (Task 9b); (f) Development of a Safety program for the ACTS Flow Loop, progress on a comprehensive safety review of all flow-loop components and operational procedures. (Task 1S); and (g) Activities towards technology transfer and developing contacts with Petroleum and service company members, and increasing the number of JIP members.

  11. Advanced Hydrogen Turbine Development

    Energy Technology Data Exchange (ETDEWEB)

    Joesph Fadok

    2008-01-01

    advanced hydrogen turbine that meets the aggressive targets set forth for the advanced hydrogen turbine, including increased rotor inlet temperature (RIT), lower total cooling and leakage air (TCLA) flow, higher pressure ratio, and higher mass flow through the turbine compared to the baseline. Maintaining efficiency with high mass flow Syngas combustion is achieved using a large high AN2 blade 4, which has been identified as a significant advancement beyond the current state-of-the-art. Preliminary results showed feasibility of a rotor system capable of increased power output and operating conditions above the baseline. In addition, several concepts were developed for casing components to address higher operating conditions. Rare earth modified bond coat for the purpose of reducing oxidation and TBC spallation demonstrated an increase in TBC spallation life of almost 40%. The results from Phase 1 identified two TBC compositions which satisfy the thermal conductivity requirements and have demonstrated phase stability up to temperatures of 1850 C. The potential to join alloys using a bonding process has been demonstrated and initial HVOF spray deposition trials were promising. The qualitative ranking of alloys and coatings in environmental conditions was also performed using isothermal tests where significant variations in alloy degradation were observed as a function of gas composition. Initial basic system configuration schematics and working system descriptions have been produced to define key boundary data and support estimation of costs. Review of existing materials in use for hydrogen transportation show benefits or tradeoffs for materials that could be used in this type of applications. Hydrogen safety will become a larger risk than when using natural gas fuel as the work done to date in other areas has shown direct implications for this type of use. Studies were conducted which showed reduced CO{sub 2} and NOx emissions with increased plant efficiency. An approach to

  12. Advanced microwave processing concepts

    Energy Technology Data Exchange (ETDEWEB)

    Lauf, R.J.; McMillan, A.D.; Paulauskas, F.L. [Oak Ridge National Laboratory, TN (United States)

    1995-05-01

    The purpose of this work is to explore the feasibility of several advanced microwave processing concepts to develop new energy-efficient materials and processes. The project includes two tasks: (1) commercialization of the variable-frequency microwave furnace; and (2) microwave curing of polymer composites. The variable frequency microwave furnace, whose initial conception and design was funded by the AIC Materials Program, will allow us, for the first time, to conduct microwave processing studies over a wide frequency range. This novel design uses a high-power traveling wave tube (TWT) originally developed for electronic warfare. By using this microwave source, one can not only select individual microwave frequencies for particular experiments, but also achieve uniform power densities over a large area by the superposition of many different frequencies. Microwave curing of thermoset resins will be studied because it hold the potential of in-situ curing of continuous-fiber composites for strong, lightweight components. Microwave heating can shorten curing times, provided issues of scaleup, uniformity, and thermal management can be adequately addressed.

  13. ADVANCED HYBRID PARTICULATE COLLECTOR

    Energy Technology Data Exchange (ETDEWEB)

    Stanley J. Miller; Grant L. Schelkoph; Grant E. Dunham

    2000-12-01

    A new concept in particulate control, called an advanced hybrid particulate collector (AHPC), is being developed under funding from the US Department of Energy. The AHPC combines the best features of electrostatic precipitators (ESPs) and baghouses in an entirely novel manner. The AHPC concept combines fabric filtration and electrostatic precipitation in the same housing, providing major synergism between the two methods, both in the particulate collection step and in transfer of dust to the hopper. The AHPC provides ultrahigh collection efficiency, overcoming the problem of excessive fine-particle emissions with conventional ESPs, and solves the problem of reentrainment and recollection of dust in conventional baghouses. Phase I of the development effort consisted of design, construction, and testing of a 5.7-m{sup 3}/min (200-acfm) working AHPC model. Results from both 8-hour parametric tests and 100-hour proof-of-concept tests with two different coals demonstrated excellent operability and greater than 99.99% fine-particle collection efficiency.

  14. Advanced manufacturing: Technology diffusion

    Energy Technology Data Exchange (ETDEWEB)

    Tesar, A.

    1995-12-01

    In this paper we examine how manufacturing technology diffuses rom the developers of technology across national borders to those who do not have the capability or resources to develop advanced technology on their own. None of the wide variety of technology diffusion mechanisms discussed in this paper are new, yet the opportunities to apply these mechanisms are growing. A dramatic increase in technology diffusion occurred over the last decade. The two major trends which probably drive this increase are a worldwide inclination towards ``freer`` markets and diminishing isolation. Technology is most rapidly diffusing from the US In fact, the US is supplying technology for the rest of the world. The value of the technology supplied by the US more than doubled from 1985 to 1992 (see the Introduction for details). History shows us that technology diffusion is inevitable. It is the rates at which technologies diffuse to other countries which can vary considerably. Manufacturers in these countries are increasingly able to absorb technology. Their manufacturing efficiency is expected to progress as technology becomes increasingly available and utilized.

  15. Advanced Power Electronics Components

    Science.gov (United States)

    Schwarze, Gene E.

    2004-01-01

    This paper will give a description and status of the Advanced Power Electronics Materials and Components Technology program being conducted by the NASA Glenn Research Center for future aerospace power applications. The focus of this research program is on the following: 1) New and/or significantly improved dielectric materials for the development of power capacitors with increased volumetric efficiency, energy density, and operating temperature. Materials being investigated include nanocrystalline and composite ceramic dielectrics and diamond-like carbon films; 2) New and/or significantly improved high frequency, high temperature, low loss soft magnetic materials for the development of transformers/inductors with increased power/energy density, electrical efficiency, and operating temperature. Materials being investigated include nanocrystalline and nanocomposite soft magnetic materials; 3) Packaged high temperature, high power density, high voltage, and low loss SiC diodes and switches. Development of high quality 4H- and 6H- SiC atomically smooth substrates to significantly improve device performance is a major emphasis of the SiC materials program; 4) Demonstration of high temperature (> 200 C) circuits using the components developed above.

  16. Advances in proof theory

    CERN Document Server

    Strahm, Thomas; Studer, Thomas

    2016-01-01

    The aim of this volume is to collect original contributions by the best specialists from the area of proof theory, constructivity, and computation and discuss recent trends and results in these areas. Some emphasis will be put on ordinal analysis, reductive proof theory, explicit mathematics and type-theoretic formalisms, and abstract computations. The volume is dedicated to the 60th birthday of Professor Gerhard Jäger, who has been instrumental in shaping and promoting logic in Switzerland for the last 25 years. It comprises contributions from the symposium “Advances in Proof Theory”, which was held in Bern in December 2013. Proof theory came into being in the twenties of the last century, when it was inaugurated by David Hilbert in order to secure the foundations of mathematics. It was substantially influenced by Gödel's famous incompleteness theorems of 1930 and Gentzen's new consistency proof for the axiom system of first order number theory in 1936. Today, proof theory is a well-established branch ...

  17. Advanced robot locomotion.

    Energy Technology Data Exchange (ETDEWEB)

    Neely, Jason C.; Sturgis, Beverly Rainwater; Byrne, Raymond Harry; Feddema, John Todd; Spletzer, Barry Louis; Rose, Scott E.; Novick, David Keith; Wilson, David Gerald; Buerger, Stephen P.

    2007-01-01

    This report contains the results of a research effort on advanced robot locomotion. The majority of this work focuses on walking robots. Walking robot applications include delivery of special payloads to unique locations that require human locomotion to exo-skeleton human assistance applications. A walking robot could step over obstacles and move through narrow openings that a wheeled or tracked vehicle could not overcome. It could pick up and manipulate objects in ways that a standard robot gripper could not. Most importantly, a walking robot would be able to rapidly perform these tasks through an intuitive user interface that mimics natural human motion. The largest obstacle arises in emulating stability and balance control naturally present in humans but needed for bipedal locomotion in a robot. A tracked robot is bulky and limited, but a wide wheel base assures passive stability. Human bipedal motion is so common that it is taken for granted, but bipedal motion requires active balance and stability control for which the analysis is non-trivial. This report contains an extensive literature study on the state-of-the-art of legged robotics, and it additionally provides the analysis, simulation, and hardware verification of two variants of a proto-type leg design.

  18. Discussion on advanced manufacturing

    Institute of Scientific and Technical Information of China (English)

    WANG Xiankui

    2007-01-01

    Advanced manufacturing consists of continuity of manufacturing,its broad sense,and the core of the manufacturing process.The technology of continuous manufacturing is discussed according to both historical and modern perspectives.The relationship between human development and manufacturing technology is also discussed.Manufacturing is a continuously evolving topic.It is not only the foundation and means of imagination,conception,the science,and the technology of material change,but also the expression of national economy,national defense,and the support industries.The broad sense of manufacturing theory,which extends the concept of manufacturing,is an important development in the 20th century.The sense is analyzed in connection with design,material forming theory,synthesis of manufacturing technology,manufacturing modes,life cycle of product,hardware and sottware,and support environment,etc.At the same time,the core action and the development of the theory and technology of process is also discussed.At the end of this paper,the development directions of mechanical manufacturing science and technology are mentioned.

  19. Recent advances of nanodosimetry.

    Science.gov (United States)

    Grosswendt, B

    2004-01-01

    The early damage to genes and cells due to ionizing radiation is initiated by the overlay of the track structure of charged particles and of the structure of radiosensitive sub-cellular volumes. As a result of this overlay, a specified number of ionizations (the ionization cluster size) is formed per primary particle. Therefore, one of the aims of nanodosimetry is to determine ionization cluster-size distributions in nanometric volumes of liquid water, as a substitute to sub-cellular structures. After a short description of the main aspects of cluster-size formation by charged particles, an overview of the advanced measuring techniques that use millimetric target volumes filled with a low-pressure gas to simulate nanometric target volumes at unit density is given. Afterwards, physical principles are discussed which are applicable to convert ionization cluster-size distributions measured in gases into those for liquid water. Finally, a tentative possibility is proposed of how to relate parameters derived from cluster-size distributions in liquid water to parameters derived from radiation-induced radiobiological experiments. PMID:15353748

  20. Recent advances of nanodosimetry

    International Nuclear Information System (INIS)

    The early damage to genes and cells due to ionizing radiation is initiated by the overlay of the track structure of charged particles and of the structure of radiosensitive sub-cellular volumes. As a result of this overlay, a specified number of ionizations (the ionization cluster size) is formed per primary particle. Therefore, one of the aims of nanodosimetry is to determine ionization cluster-size distributions in nano-metric volumes of liquid water, as a substitute to sub-cellular structures. After a short description of the main aspects of cluster-size formation by charged particles, an overview of the advanced measuring techniques that use millimetric target volumes filled with a low-pressure gas to simulate nano-metric target volumes at unit density is given. Afterwards, physical principles are discussed which are applicable to convert ionization cluster-size distributions measured in gases into those for liquid water. Finally, a tentative possibility is proposed of how to relate parameters derived from cluster-size distributions in liquid water to parameters derived from radiation-induced radiobiological experiments. (authors)

  1. Advanced superconducting optical detectors

    International Nuclear Information System (INIS)

    We have investigated advanced superconducting optical and infrared detectors for their integration with superconductive active circuits. The detectors are based on ultra-thin NbN striplines. NbN is the material of choice for single photon optical and infrared detectors, as already demonstrated in the literature. The detectors so far proposed are based on conceptually simple, although difficult to realize, sub-micrometric meander type structures. Most applications of such detectors require some treatment of the signal generated, either as pulse shaping or signal amplification, to fully exploit the detection capabilities, such as sub-ns response time and proportional response. We have developed a room temperature process that, while preserving reasonable superconducting properties of NbN, allows a simple integration of the detectors in Nb-based circuits. Moreover we have developed a passivation technique, by using a protective AlN layer on top of the NbN one. The developed technology allows complex detector configurations, such as integrated RSFQ circuits or SQUID readout, to be relatively easily realized. The response of our NbN strip to photon irradiation will be presented

  2. [Advances in Molecular Cloning].

    Science.gov (United States)

    Ashwini, M; Murugan, S B; Balamurugan, S; Sathishkumar, R

    2016-01-01

    "Molecular cloning" meaning creation of recombinant DNA molecules has impelled advancement throughout life sciences. DNA manipulation has become easy due to powerful tools showing exponential growth in applications and sophistication of recombinant DNA technology. Cloning genes has become simple what led to an explosion in the understanding of gene function by seamlessly stitching together multiple DNA fragments or by the use of swappable gene cassettes, maximizing swiftness and litheness. A novel archetype might materialize in the near future with synthetic biology techniques that will facilitate quicker assembly and iteration of DNA clones, accelerating the progress of gene therapy vectors, recombinant protein production processes and new vaccines by in vitro chemical synthesis of any in silico-specified DNA construct. The advent of innovative cloning techniques has opened the door to more refined applications such as identification and mapping of epigenetic modifications and high-throughput assembly of combinatorial libraries. In this review, we will examine the major breakthroughs in cloning techniques and their applications in various areas of biological research that have evolved mainly due to easy construction of novel expression systems. PMID:27028806

  3. Recent advances in sarcoidosis.

    Science.gov (United States)

    Morgenthau, Adam S; Iannuzzi, Michael C

    2011-01-01

    Sarcoidosis, a systemic granulomatous disease of undetermined etiology, is characterized by a variable clinical presentation and course. During the past decade, advances have been made in the study of sarcoidosis. The multicenter ACCESS (A Case Control Etiologic Study of Sarcoidosis) trial recruited > 700 subjects with newly diagnosed sarcoidosis and matched control subjects. Investigators were unable to identify a single cause of sarcoidosis, but ACCESS paved the way for subsequent etiologic studies. The Mycobacterium tuberculosis catalase-peroxidase protein has been identified as a potential sarcoidosis antigen. Genetic aspects of the disease have been elucidated further. Genome-wide scans have identified candidate genes. Gene expression analyses have defined cytokine dysregulation in sarcoidosis more clearly. Although the criteria for diagnosis have not changed, sarcoidosis remains a diagnosis of exclusion best supported by a tissue biopsy specimen that demonstrates noncaseating granulomas in a patient with compatible clinical and radiologic features of the disease. Endobronchial ultrasound-guided transbronchial needle aspiration of mediastinal lymph nodes has facilitated diagnosis, often eliminating the need for more invasive procedures, such as mediastinoscopy. PET scanning has proven valuable in locating occult sites of active disease. Currently, no reliable prognostic biomarkers have been identified. The tumor necrosis factor inhibitors, a relatively new class of agents, have been used in patients with refractory disease. It is unclear whether phosphodiesterase-5 inhibitors, prostaglandin analogs, or endothelin antagonists should be used for the treatment of sarcoidosis-associated pulmonary hypertension. PMID:21208877

  4. Advanced worker protection system

    International Nuclear Information System (INIS)

    The Department of Energy (DOE) is in the process of defining the magnitude and diversity of Decontamination and Decommissioning (D ampersand D) obligations at its numerous sites. The DOE believes that existing technologies are inadequate to solve many challenging problems such as how to decontaminate structures and equipment cost effectively, what to do with materials and wastes generated, and how to adequately protect workers and the environment. Preliminary estimates show a tremendous need for effective use of resources over a relatively long period (over 30 years). Several technologies are being investigated which can potentially reduce D ampersand D costs while providing appropriate protection to DOE workers. The DOE recognizes that traditional methods used by the EPA in hazardous waste site clean up activities are insufficient to provide the needed protection and worker productivity demanded by DOE D ampersand D programs. As a consequence, new clothing and equipment which can adequately protect workers while providing increases in worker productivity are being sought for implementation at DOE sites. This project describes the development of an Advanced Worker Protection System (AWPS) which will include a life-support backpack with liquid air for cooling and as a supply of breathing gas, protective clothing, respirators, communications, and support equipment

  5. Advanced worker protection system

    Energy Technology Data Exchange (ETDEWEB)

    Caldwell, B.; Duncan, P.; Myers, J. [Oceaneering Space Systems, Houston, TX (United States)

    1995-10-01

    The Department of Energy (DOE) is in the process of defining the magnitude and diversity of Decontamination and Decommissioning (D&D) obligations at its numerous sites. The DOE believes that existing technologies are inadequate to solve many challenging problems such as how to decontaminate structures and equipment cost effectively, what to do with materials and wastes generated, and how to adequately protect workers and the environment. Preliminary estimates show a tremendous need for effective use of resources over a relatively long period (over 30 years). Several technologies are being investigated which can potentially reduce D&D costs while providing appropriate protection to DOE workers. The DOE recognizes that traditional methods used by the EPA in hazardous waste site clean up activities are insufficient to provide the needed protection and worker productivity demanded by DOE D&D programs. As a consequence, new clothing and equipment which can adequately protect workers while providing increases in worker productivity are being sought for implementation at DOE sites. This project describes the development of an Advanced Worker Protection System (AWPS) which will include a life-support backpack with liquid air for cooling and as a supply of breathing gas, protective clothing, respirators, communications, and support equipment.

  6. Advanced microwave processing concepts

    Energy Technology Data Exchange (ETDEWEB)

    Lauf, R.J.; McMillan, A.D.; Paulauskas, F.L. [Oak Ridge National Lab., TN (United States)

    1997-04-01

    The purpose of this work is to explore the feasibility of several advanced microwave processing concepts to develop new energy-efficient materials and processes. The project includes two tasks: (1) commercialization of the variable-frequency microwave furnace; and (2) microwave curing of polymeric materials. The variable frequency microwave furnace, whose initial conception and design was funded by the AIM Materials Program, allows the authors, for the first time, to conduct microwave processing studies over a wide frequency range. This novel design uses a high-power traveling wave tube (TWT) originally developed for electronic warfare. By using this microwave source, one can not only select individual microwave frequencies for particular experiments, but also achieve uniform power densities over a large area by the superposition of many different frequencies. Microwave curing of various thermoset resins will be studied because it holds the potential of in-situ curing of continuous-fiber composites for strong, lightweight components or in-situ curing of adhesives, including metal-to-metal. Microwave heating can shorten curing times, provided issues of scaleup, uniformity, and thermal management can be adequately addressed.

  7. ADVANCED CUTTINGS TRANSPORT STUDY

    Energy Technology Data Exchange (ETDEWEB)

    Troy Reed; Stefan Miska; Nicholas Takach; Kaveh Ashenayi; Gerald Kane; Mark Pickell; Len Volk; Mike Volk; Affonso Lourenco; Evren Ozbayoglu; Lei Zhou

    2002-01-30

    This is the second quarterly progress report for Year 3 of the ACTS project. It includes a review of progress made in: (1) Flow Loop development and (2) research tasks during the period of time between Oct 1, 2001 and Dec. 31, 2001. This report presents a review of progress on the following specific tasks: (a) Design and development of an Advanced Cuttings Transport Facility (Task 3: Addition of a Cuttings Injection/Collection System), (b) Research project (Task 6): ''Study of Cuttings Transport with Foam Under LPAT Conditions (Joint Project with TUDRP)'', (c) Research project (Task 9): ''Study of Foam Flow Behavior Under EPET Conditions'', (d) Research project (Task 10): ''Study of Cuttings Transport with Aerated Mud Under Elevated Pressure and Temperature Conditions'', (e) Research on instrumentation tasks to measure: Cuttings concentration and distribution in a flowing slurry (Task 11), and Foam properties while transporting cuttings. (Task 12), (f) Development of a Safety program for the ACTS Flow Loop. Progress on a comprehensive safety review of all flow-loop components and operational procedures. (Task 1S). (g) Activities towards technology transfer and developing contacts with Petroleum and service company members, and increasing the number of JIP members.

  8. Advanced verification topics

    CERN Document Server

    Bhattacharya, Bishnupriya; Hall, Gary; Heaton, Nick; Kashai, Yaron; Khan Neyaz; Kirshenbaum, Zeev; Shneydor, Efrat

    2011-01-01

    The Accellera Universal Verification Methodology (UVM) standard is architected to scale, but verification is growing and in more than just the digital design dimension. It is growing in the SoC dimension to include low-power and mixed-signal and the system integration dimension to include multi-language support and acceleration. These items and others all contribute to the quality of the SOC so the Metric-Driven Verification (MDV) methodology is needed to unify it all into a coherent verification plan. This book is for verification engineers and managers familiar with the UVM and the benefits it brings to digital verification but who also need to tackle specialized tasks. It is also written for the SoC project manager that is tasked with building an efficient worldwide team. While the task continues to become more complex, Advanced Verification Topics describes methodologies outside of the Accellera UVM standard, but that build on it, to provide a way for SoC teams to stay productive and profitable.

  9. MICROENCAPSULATION: ADVANCEMENTS IN APPLICATIONS

    Directory of Open Access Journals (Sweden)

    Arsh Chanana

    2013-02-01

    Full Text Available Microcapsule is a tiny sphere including core material/internal phase or fill, coated with/surrounded by wall know as shell, coating or membrane. The usual size range of the microcapsule lies between 1 to 1000 μm. The technique is usually applied for targeted drug delivery, protection of the molecule and stability if the core material. Microencapsulation system offers potential advantages over conventional drug delivery systems and also established as unique carrier systems for many pharmaceuticals. This article contains the traditional and the recent pharmaceutical applications of microecapsules. The microcapsules are widely applied in pharmaceutical for Novel drug Delivery System (NDDS, latest formulations, Delivery of DNA Vaccines, Pro Drug Approach, Biodegradable and biocompatible material. Other then pharmaceutical microcapsules are widely used in delivery of probiotic, pesticide industry, food technology, beverages and cell immobilization etc. Although significant advances have been made in the field of microencapsulation, still many challenges need to be rectified during the appropriate selection of core materials, coating materials and process techniques.

  10. Advances in neutron scattering research

    International Nuclear Information System (INIS)

    This issue of the Supplement to Journal of the Physical Society of Japan collects invited and contributed papers from the first International Symposium on Advanced Science Research (ASR-2000) 'Advances in Neutron Scattering Research'. The 182 of the presented papers are indexed individually. (J.P.N.)

  11. Advanced Infrared Technology and Applications

    OpenAIRE

    Ovidio Salvetti; Laura Abbozzo Ronchi; Carlo Corsi; Antoni Rogalski; Marija Strojnik

    2013-01-01

    Nowadays, advanced infrared techniques are a key ingredient in disparate applications, ranging from medical diagnostics and treatment to industrial inspection and environmental monitoring. We believe that the success of such infrared applications highly depends on a continuous exchange between scientific advances and technological progresses.

  12. Research advances in geriatric depression

    OpenAIRE

    Alexopoulos, George S.; KELLY JR., ROBERT E.

    2009-01-01

    Technical advances have facilitated the exploration of factors related to geriatric depression and have helped generate novel biological and psychosocial treatment approaches. This review summarizes the main advancements in epidemiology, clinical presentation and course, genetics, and other areas of biological research. Treatment interventions outlined in this paper include electroconvulsive therapy, repetitive transcranial magnetic stimulation, magnetic seizure therapy, vagus nerve stimulati...

  13. Index of competences Advanced Materials

    International Nuclear Information System (INIS)

    This index gathers the main french competences in advanced materials field (university laboratories, research and development organisms, technical centers, experts...). The concerned advanced materials are plastics and technical polymers, metals and alloys, composite materials, technical ceramics, glasses, paper, wood and textile. A PC computer version is also available. (A.B.)

  14. Laser machining of advanced materials

    CERN Document Server

    Dahotre, Narendra B

    2011-01-01

    Advanced materialsIntroductionApplicationsStructural ceramicsBiomaterials CompositesIntermetallicsMachining of advanced materials IntroductionFabrication techniquesMechanical machiningChemical Machining (CM)Electrical machiningRadiation machining Hybrid machiningLaser machiningIntroductionAbsorption of laser energy and multiple reflectionsThermal effectsLaser machining of structural ceramicsIntrodu

  15. Advanced LBB methodology and considerations

    Energy Technology Data Exchange (ETDEWEB)

    Olson, R.; Rahman, S.; Scott, P. [Battelle, Columbus, OH (United States)] [and others

    1997-04-01

    LBB applications have existed in many industries and more recently have been applied in the nuclear industry under limited circumstances. Research over the past 10 years has evolved the technology so that more advanced consideration of LBB can now be given. Some of the advanced considerations for nuclear plants subjected to seismic loading evaluations are summarized in this paper.

  16. Advanced Analysis of Nontraditional Machining

    CERN Document Server

    Tsai, Hung-Yin

    2013-01-01

    Nontraditional machining utilizes thermal, chemical, electrical, mechanical and optical sources of energy to form and cut materials. Advanced Analysis of Nontraditional Machining explains in-depth how each of these advanced machining processes work, their machining system components, and process variables and industrial applications, thereby offering advanced knowledge and scientific insight. This book also documents the latest and frequently cited research results of a few key nonconventional machining processes for the most concerned topics in industrial applications, such as laser machining, electrical discharge machining, electropolishing of die and mold, and wafer processing for integrated circuit manufacturing. This book also: Fills the gap of the advanced knowledge of nonconventional machining between industry and research Documents latest and frequently cited research of key nonconventional machining processes for the most sought after topics in industrial applications Demonstrates advanced multidisci...

  17. Advanced teleoperation in nuclear applications

    International Nuclear Information System (INIS)

    A new generation of integrated remote maintenance systems is being developed to meet the needs of future nuclear fuel reprocessing at the Oak Ridge National Laboratory. Development activities cover all aspects of an advanced teleoperated maintenance system with particular emphasis on a new force-reflecting servomanipulator concept. The new manipulator, called the advanced servomanipulator, is microprocessor controlled and is designed to achieve force-reflection performance near that of mechanical master/slave manipulators. The advanced servomanipulator uses a gear-drive transmission which permits modularization for remote maintainability (by other advanced servomanipulators) and increases reliability. Human factors analysis has been used to develop an improved man/machine interface concept based upon colorgraphic displays and menu-driven tough screens. Initial test and evaluation of two advanced servomanipulator slave arms and several other development components have begun. 9 references, 5 figures

  18. Predicting epileptic seizures in advance.

    Directory of Open Access Journals (Sweden)

    Negin Moghim

    Full Text Available Epilepsy is the second most common neurological disorder, affecting 0.6-0.8% of the world's population. In this neurological disorder, abnormal activity of the brain causes seizures, the nature of which tend to be sudden. Antiepileptic Drugs (AEDs are used as long-term therapeutic solutions that control the condition. Of those treated with AEDs, 35% become resistant to medication. The unpredictable nature of seizures poses risks for the individual with epilepsy. It is clearly desirable to find more effective ways of preventing seizures for such patients. The automatic detection of oncoming seizures, before their actual onset, can facilitate timely intervention and hence minimize these risks. In addition, advance prediction of seizures can enrich our understanding of the epileptic brain. In this study, drawing on the body of work behind automatic seizure detection and prediction from digitised Invasive Electroencephalography (EEG data, a prediction algorithm, ASPPR (Advance Seizure Prediction via Pre-ictal Relabeling, is described. ASPPR facilitates the learning of predictive models targeted at recognizing patterns in EEG activity that are in a specific time window in advance of a seizure. It then exploits advanced machine learning coupled with the design and selection of appropriate features from EEG signals. Results, from evaluating ASPPR independently on 21 different patients, suggest that seizures for many patients can be predicted up to 20 minutes in advance of their onset. Compared to benchmark performance represented by a mean S1-Score (harmonic mean of Sensitivity and Specificity of 90.6% for predicting seizure onset between 0 and 5 minutes in advance, ASPPR achieves mean S1-Scores of: 96.30% for prediction between 1 and 6 minutes in advance, 96.13% for prediction between 8 and 13 minutes in advance, 94.5% for prediction between 14 and 19 minutes in advance, and 94.2% for prediction between 20 and 25 minutes in advance.

  19. ADVANCED CUTTINGS TRANSPORT STUDY

    Energy Technology Data Exchange (ETDEWEB)

    Troy Reed; Stefan Miska; Nicholas Takach; Kaveh Ashenayi; Gerald Kane; Mark Pickell; Len Volk; Mike Volk; Barkim Demirdal; Affonso Lourenco; Evren Ozbayoglu; Paco Vieira; Lei Zhou

    2000-01-30

    This is the second quarterly progress report for Year 2 of the ACTS project. It includes a review of progress made in Flow Loop development and research during the period of time between Oct 1, 2000 and December 31, 2000. This report presents a review of progress on the following specific tasks: (a) Design and development of an Advanced Cuttings Transport Facility (Task 2: Addition of a foam generation and breaker system), (b) Research project (Task 6): ''Study of Cuttings Transport with Foam Under LPAT Conditions (Joint Project with TUDRP)'', (c) Research project (Task 7): ''Study of Cuttings Transport with Aerated Muds Under LPAT Conditions (Joint Project with TUDRP)'', (d) Research project (Task 8): ''Study of Flow of Synthetic Drilling Fluids Under Elevated Pressure and Temperature Conditions'', (e) Research project (Task 9): ''Study of Foam Flow Behavior Under EPET Conditions'', (f) Research project (Task 10): ''Study of Cuttings Transport with Aerated Mud Under Elevated Pressure and Temperature Conditions'', (g) Research on instrumentation tasks to measure: Cuttings concentration and distribution in a flowing slurry (Task 11), and Foam properties while transporting cuttings. (Task 12), (h) Development of a Safety program for the ACTS Flow Loop. Progress on a comprehensive safety review of all flow-loop components and operational procedures. (Task 1S). (i) Activities towards technology transfer and developing contacts with Petroleum and service company members, and increasing the number of JIP members. The tasks Completed During This Quarter are Task 7 and Task 8.

  20. ADVANCED CUTTINGS TRANSPORT STUDY

    Energy Technology Data Exchange (ETDEWEB)

    Troy Reed; Stefan Miska; Nicholas Takach; Kaveh Ashenayi; Gerald Kane; Mark Pickell; Len Volk; Mike Volk; Barkim Demirdal; Affonso Lourenco; Evren Ozbayoglu; Paco Vieira

    2000-10-30

    This is the first quarterly progress report for Year 2 of the ACTS project. It includes a review of progress made in Flow Loop development and research during the period of time between July 14, 2000 and September 30, 2000. This report presents information on the following specific tasks: (a) Progress in Advanced Cuttings Transport Facility design and development (Task 2), (b) Progress on research project (Task 8): ''Study of Flow of Synthetic Drilling Fluids Under Elevated Pressure and Temperature Conditions'', (c) Progress on research project (Task 6): ''Study of Cuttings Transport with Foam Under LPAT Conditions (Joint Project with TUDRP)'', (d) Progress on research project (Task 7): ''Study of Cuttings Transport with Aerated Muds Under LPAT Conditions (Joint Project with TUDRP)'', (e) Progress on research project (Task 9): ''Study of Foam Flow Behavior Under EPET Conditions'', (f) Initiate research on project (Task 10): ''Study of Cuttings Transport with Aerated Mud Under Elevated Pressure and Temperature Conditions'', (g) Progress on instrumentation tasks to measure: Cuttings concentration and distribution (Tasks 11), and Foam properties (Task 12), (h) Initiate a comprehensive safety review of all flow-loop components and operational procedures. Since the previous Task 1 has been completed, we will now designate this new task as: (Task 1S). (i) Activities towards technology transfer and developing contacts with Petroleum and service company members, and increasing the number of JIP members.

  1. State Technologies Advancement Collaborative

    Energy Technology Data Exchange (ETDEWEB)

    David S. Terry

    2012-01-30

    The U. S. Department of Energy (DOE), National Association of State Energy Officials (NASEO), and Association of State Energy Research and Technology Transfer Institutions (ASERTTI) signed an intergovernmental agreement on November 14, 2002, that allowed states and territories and the Federal Government to better collaborate on energy research, development, demonstration and deployment (RDD&D) projects. The agreement established the State Technologies Advancement Collaborative (STAC) which allowed the states and DOE to move RDD&D forward using an innovative competitive project selection and funding process. A cooperative agreement between DOE and NASEO served as the contracting instrument for this innovative federal-state partnership obligating funds from DOE's Office of Energy Efficiency and Renewable Energy and Office of Fossil Energy to plan, fund, and implement RDD&D projects that were consistent with the common priorities of the states and DOE. DOE's Golden Field Office provided Federal oversight and guidance for the STAC cooperative agreement. The STAC program was built on the foundation of prior Federal-State efforts to collaborate on and engage in joint planning for RDD&D. Although STAC builds on existing, successful programs, it is important to note that it was not intended to replace other successful joint DOE/State initiatives such as the State Energy Program or EERE Special Projects. Overall the STAC process was used to fund, through three competitive solicitations, 35 successful multi-state research, development, deployment, and demonstration projects with an overall average non-federal cost share of 43%. Twenty-two states were awarded at least one prime contract, and organizations in all 50 states and some territories were involved as subcontractors in at least one STAC project. Projects were funded in seven program areas: (1) Building Technologies, (2) Industrial Technologies, (3) Transportation Technologies, (4) Distributed Energy

  2. Advancements in CIAU methodology

    International Nuclear Information System (INIS)

    Best-Estimate calculation results from complex thermal-hydraulic system codes (like Relap5, Cathare, Athlet, Trace, etc.) are affected by unavoidable approximations that are unpredictable without the use of computational tools that account for the various sources of uncertainty. Therefore the use of best-estimate codes within the reactor technology, either for design or safety purposes, implies understanding and accepting the limitations and the deficiencies of those codes. Uncertainties may have different origins ranging from the approximation of the models, to the approximation of the numerical solution, and to the lack of precision of the values adopted for boundary and initial conditions. The amount of uncertainty that affects a calculation may strongly depend upon the codes and the modeling techniques (i.e. the code's users). A consistent and robust uncertainty methodology must be developed taking into consideration all the above aspects. The CIAU (Code with the capability of Internal Assessment of Uncertainty) and the UMAE (Uncertainty Methodology based on Accuracy Evaluation) methods have been developed by University of Pisa in the framework of a long lasting research activities started since 80's and involving several researchers. CIAU is extensively discussed in the available technical literature, Refs. [1, 2, 3, 4, 5, 6, 7], and tens of additional relevant papers, that provide comprehensive details about the method, can be found in the bibliography lists of the above references. Therefore, the present paper supplies only 'spot-information' about CIAU and focuses mostly on the advancements of the methodology, that constitute the original contributions of the present work. In particular, the extension of the uncertainty database and the development of a procedure for the 'internal' qualification of the method are discussed. Both aspects result in a more accurate CIAU uncertainty evaluation as they contribute respectively to improve the statistic (in fact

  3. Towards advanced code simulators

    International Nuclear Information System (INIS)

    The Central Electricity Generating Board (CEGB) uses advanced thermohydraulic codes extensively to support PWR safety analyses. A system has been developed to allow fully interactive execution of any code with graphical simulation of the operator desk and mimic display. The system operates in a virtual machine environment, with the thermohydraulic code executing in one virtual machine, communicating via interrupts with any number of other virtual machines each running other programs and graphics drivers. The driver code itself does not have to be modified from its normal batch form. Shortly following the release of RELAP5 MOD1 in IBM compatible form in 1983, this code was used as the driver for this system. When RELAP5 MOD2 became available, it was adopted with no changes needed in the basic system. Overall the system has been used for some 5 years for the analysis of LOBI tests, full scale plant studies and for simple what-if studies. For gaining rapid understanding of system dependencies it has proved invaluable. The graphical mimic system, being independent of the driver code, has also been used with other codes to study core rewetting, to replay results obtained from batch jobs on a CRAY2 computer system and to display suitably processed experimental results from the LOBI facility to aid interpretation. For the above work real-time execution was not necessary. Current work now centers on implementing the RELAP 5 code on a true parallel architecture machine. Marconi Simulation have been contracted to investigate the feasibility of using upwards of 100 processors, each capable of a peak of 30 MIPS to run a highly detailed RELAP5 model in real time, complete with specially written 3D core neutronics and balance of plant models. This paper describes the experience of using RELAP5 as an analyzer/simulator, and outlines the proposed methods and problems associated with parallel execution of RELAP5

  4. Advanced Magnetoimpedance Sensors

    KAUST Repository

    Li, Bodong

    2015-02-01

    This thesis is concerned with the advanced topics of thin film magnetoimpedance (MI) sensors. The author proposes and develops novel MI sensors that target on the challenges arising from emerging applications such as flexible electronics, passive wireless sensing, etc. In the study of flexible MI sensor, the investigated sensors of NiFe/Cu/NiFe tri-layersare fabricated on three flexible substrates having different surface roughness: Kapton, standard and premiumphotopaper. Sensitivity versus substrate roughness analysis is carried out for the selection of optimal substrate material. The high magnetic sensing performance is achieved by using Kapton substrate. Stress simulation, incorporated with the theory of magnetostriction effect, reveals the material composition of Ni/Fe being as a key factor of the stress dependent MI effect for the flexible MI sensors. In the development of MI-SAW device for passive wireless magnetic field sensing, NiFe/Cu/NiFe tri-layersand interdigital transducers(IDT) are designed and fabricated on a single piece of LiNbO3substrate, providing a high degree of integration and the advantage of standard microfabrication. The double-electrodeIDT has been utilized and proven to have an optimal sensing performance in comparison to the bi-directional IDT design. The optimized high frequency performance of the thin film MI sensor results in a MI-SAW passive wireless magnetic sensor with high magnetic sensitivity comparing to the MI microwire approach. Benefiting from the high degree of integration of the MI thin film element, in the following study, two additional sensing elements are integrated to the SAW device to have a multifunctional passive wireless sensor with extended temperature and humidity sensing capabilities. Analytical models havebeen developed to eliminate the crossovers of different sensing signals through additional reference IDTs, resulting in a multifunctional passive wireless sensor with the capability of detecting all three

  5. ADVANCED TURBINE SYSTEMS PROGRAM

    Energy Technology Data Exchange (ETDEWEB)

    Sy Ali

    2002-03-01

    The market for power generation equipment is undergoing a tremendous transformation. The traditional electric utility industry is restructuring, promising new opportunities and challenges for all facilities to meet their demands for electric and thermal energy. Now more than ever, facilities have a host of options to choose from, including new distributed generation (DG) technologies that are entering the market as well as existing DG options that are improving in cost and performance. The market is beginning to recognize that some of these users have needs beyond traditional grid-based power. Together, these changes are motivating commercial and industrial facilities to re-evaluate their current mix of energy services. One of the emerging generating options is a new breed of advanced fuel cells. While there are a variety of fuel cell technologies being developed, the solid oxide fuel cells (SOFC) and molten carbonate fuel cells (MCFC) are especially promising, with their electric efficiency expected around 50-60 percent and their ability to generate either hot water or high quality steam. In addition, they both have the attractive characteristics of all fuel cells--relatively small siting footprint, rapid response to changing loads, very low emissions, quiet operation, and an inherently modular design lending itself to capacity expansion at predictable unit cost with reasonably short lead times. The objectives of this project are to:(1) Estimate the market potential for high efficiency fuel cell hybrids in the U.S.;(2) Segment market size by commercial, industrial, and other key markets;(3) Identify and evaluate potential early adopters; and(4) Develop results that will help prioritize and target future R&D investments. The study focuses on high efficiency MCFC- and SOFC-based hybrids and competing systems such as gas turbines, reciprocating engines, fuel cells and traditional grid service. Specific regions in the country have been identified where these

  6. Advanced Geothermal Turbodrill

    Energy Technology Data Exchange (ETDEWEB)

    W. C. Maurer

    2000-05-01

    Approximately 50% of the cost of a new geothermal power plant is in the wells that must be drilled. Compared to the majority of oil and gas wells, geothermal wells are more difficult and costly to drill for several reasons. First, most U.S. geothermal resources consist of hot, hard crystalline rock formations which drill much slower than the relatively soft sedimentary formations associated with most oil and gas production. Second, high downhole temperatures can greatly shorten equipment life or preclude the use of some technologies altogether. Third, producing viable levels of electricity from geothermal fields requires the use of large diameter bores and a high degree of fluid communication, both of which increase drilling and completion costs. Optimizing fluid communication often requires creation of a directional well to intersect the best and largest number of fracture capable of producing hot geothermal fluids. Moineau motor stators made with elastomers cannot operate at geothermal temperatures, so they are limited to the upper portion of the hole. To overcome these limitations, Maurer Engineering Inc. (MEI) has developed a turbodrill that does not use elastomers and therefore can operate at geothermal temperatures. This new turbodrill uses a special gear assembly to reduce the output speed, thus allowing a larger range of bit types, especially tri-cone roller bits, which are the bits of choice for drilling hard crystalline formations. The Advanced Geothermal Turbodrill (AGT) represents a significant improvement for drilling geothermal wells and has the potential to significantly reduce drilling costs while increasing production, thereby making geothermal energy less expensive and better able to compete with fossil fuels. The final field test of the AGT will prepare the tool for successful commercialization.

  7. LTE advanced 3GPP solution for IMT-advanced

    CERN Document Server

    Holma, Harri

    2012-01-01

    From the editors of the highly successful LTE for UMTS: Evolution to LTE-Advanced, this new book examines the main technical enhancements brought by LTE-Advanced, thoroughly covering 3GPP Release 10 specifications and the main items in Release 11. Using illustrations, graphs and real-life scenarios, the authors systematically lead readers through this cutting-edge topic to provide an outlook on existing technologies as well as possible future developments. The book is structured to follow the main technical areas that will be enhanced by the LTE-Advanced specifications. The mai

  8. NATO Advanced Study Institute on Advances in Chemical Reaction Dynamics

    CERN Document Server

    Capellos, Christos

    1986-01-01

    This book contains the formal lectures and contributed papers presented at the NATO Advanced Study Institute on. the Advances in Chemical Reaction Dynamics. The meeting convened at the city of Iraklion, Crete, Greece on 25 August 1985 and continued to 7 September 1985. The material presented describes the fundamental and recent advances in experimental and theoretical aspects of, reaction dynamics. A large section is devoted to electronically excited states, ionic species, and free radicals, relevant to chemical sys­ tems. In addition recent advances in gas phase polymerization, formation of clusters, and energy release processes in energetic materials were presented. Selected papers deal with topics such as the dynamics of electric field effects in low polar solutions, high electric field perturbations and relaxation of dipole equilibria, correlation in picosecond/laser pulse scattering, and applications to fast reaction dynamics. Picosecond transient Raman spectroscopy which has been used for the elucidati...

  9. Advanced Space Power Systems (ASPS): Advanced Energy Storage Systems Project

    Data.gov (United States)

    National Aeronautics and Space Administration — The development of high specific energy devices will enable NASA’s future robotic and human-exploration missions.  The need for advances in energy...

  10. Advanced Wavefront Control Techniques

    Energy Technology Data Exchange (ETDEWEB)

    Olivier, S S; Brase, J M; Avicola, K; Thompson, C A; Kartz, M W; Winters, S; Hartley, R; Wihelmsen, J; Dowla, F V; Carrano, C J; Bauman, B J; Pennington, D M; Lande, D; Sawvel, R M; Silva, D A; Cooke, J B; Brown, C G

    2001-02-21

    this project, work was performed in four areas (1) advanced modeling tools for deformable mirrors (2) low-order wavefront correctors with Alvarez lenses, (3) a direct phase measuring heterdyne wavefront sensor, and (4) high-spatial-frequency wavefront control using spatial light modulators.

  11. Advanced Aerogel Technology

    Science.gov (United States)

    Jones, Steven

    2013-01-01

    The JPL Aerogel Laboratory has made aerogels for NASA flight missions, e.g., Stardust, 2003 Mars Exploration Rovers and the 2011 Mars Science Laboratory, as well as NASA research projects for the past 14 years. During that time it has produced aerogels of a range of shapes, sizes, densities and compositions. Research is ongoing in the development of aerogels for future sample capture and return missions and for thermal insulation for both spacecraft and scientific instruments. For the past several years, the JPL Aerogel Laboratory has been developing, producing and testing a new composite material for use as the high temperature thermal insulation in the Advanced Sterling Radioisotope Generator (ASRG) being developed by Lockheed Martin and NASA. The composite is made up of a glass fiber felt, silica aerogel, Titania powder, and silica powder. The oxide powders are included to reduce irradiative heat transport at elevated temperatures. These materials have thermal conductivity values that are the same as the best commercially produced high temperature insulation materials, and yet are 40% lighter. By greatly reducing the amount of oxide powder in the composite, the density, and therefore for the value of the thermal conductivity, would be reduced. The JPL Aerogel Laboratory has experimented with using glass fiber felt, expanded glass fiber felt and loose fibers to add structural integrity to silica aerogels. However, this work has been directed toward high temperature applications. By conducting a brief investigation of the optimal combination of fiber reinforcement and aerogel density, a durable, extremely efficient thermal insulation material for ambient temperature applications would be produced. If a transparent thermal insulation is desired, then aerogel is an excellent candidate material. At typical ambient temperatures, silica aerogel prevents the transport of heat via convection and conduction due to its highly porous nature. To prevent irradiative thermal

  12. 28 CFR 104.22 - Advance Benefits.

    Science.gov (United States)

    2010-07-01

    ... 28 Judicial Administration 2 2010-07-01 2010-07-01 false Advance Benefits. 104.22 Section 104.22... Filing for Compensation; Application for Advance Benefits § 104.22 Advance Benefits. (a) Advance Benefits. Eligible Claimants may apply for immediate “Advance Benefits” in a fixed amount as follows: (1) $50,000...

  13. Advanced fuel technology and performance

    International Nuclear Information System (INIS)

    The purpose of the Advisory Group Meeting on Advanced Fuel Technology and Performance was to review the experience of advanced fuel fabrication technology, its performance, peculiarities of the back-end of the nuclear fuel cycle with regard to all types of reactors and to outline the future trends. As a result of the meeting recommendations were made for the future conduct of work on advanced fuel technology and performance. A separate abstract was prepared for each of the 20 papers in this issue

  14. Advanced Green Micropropulsion System Project

    Data.gov (United States)

    National Aeronautics and Space Administration — Systima in collaboration with the University of Washington will develop a high performance, advanced green monopropellant microthruster (0.1 – 1.0 N) for...

  15. Recent advances in radiation Oncology

    International Nuclear Information System (INIS)

    Recent technical advances, including megavoltage radiation therapy machines, computerized treatment planning systems, and computed tomography scans, have affected veterinary radiation oncology. his equipment permits far better tumor definition and dose delivery than was possible in the past. In addition, newer anesthetic agents, more dedicated equipment, and willingness of owners to spend more money for treatment have permitted fractionation schedules that can better exploit advances in radiobiology. The challenge now is to use radiobiologic and tumor biology information to make the most effective use of radiation therapy. More collaboration among surgical, medical, and radiation oncologists should result in more effective use of combined-modality treatment for tumors. This article focuses on the recent technical advances and on application of these advances to specific tumor types

  16. Advanced Carbothermal Electric Reactor Project

    Data.gov (United States)

    National Aeronautics and Space Administration — The overall objective of the Phase 1 effort was to demonstrate the technical feasibility of the Advanced Carbothermal Electric (ACE) Reactor concept. Unlike...

  17. Advanced Mechatronics and MEMS Devices

    CERN Document Server

    2013-01-01

    Advanced Mechatronics and MEMS Devicesdescribes state-of-the-art MEMS devices and introduces the latest technology in electrical and mechanical microsystems. The evolution of design in microfabrication, as well as emerging issues in nanomaterials, micromachining, micromanufacturing and microassembly are all discussed at length in this volume. Advanced Mechatronics also provides a reader with knowledge of MEMS sensors array, MEMS multidimensional accelerometer, artificial skin with imbedded tactile components, as well as other topics in MEMS sensors and transducers. The book also presents a number of topics in advanced robotics and an abundance of applications of MEMS in robotics, like reconfigurable modular snake robots, magnetic MEMS robots for drug delivery and flying robots with adjustable wings, to name a few. This book also: Covers the fundamentals of advanced mechatronics and MEMS devices while also presenting new state-of-the-art methodology and technology used in the application of these devices Prese...

  18. Advanced Superconducting Test Accelerator (ASTA)

    Data.gov (United States)

    Federal Laboratory Consortium — The Advanced Superconducting Test Accelerator (ASTA) facility will be based on upgrades to the existing NML pulsed SRF facility. ASTA is envisioned to contain 3 to...

  19. Advanced Active Acoustics Lab (AAAL)

    Data.gov (United States)

    Federal Laboratory Consortium — The Advanced Active Acoustics Lab (AAAL) is a state-of-the-art Undersea Warfare (USW) acoustic data analysis facility capable of both active and passive underwater...

  20. Advanced Carbothermal Electric Reactor Project

    Data.gov (United States)

    National Aeronautics and Space Administration — ORBITEC proposes to develop the Advanced Carbothermal Electric (ACE) reactor to efficiently extract oxygen from lunar regolith. Unlike state-of-the-art carbothermal...

  1. Ohio Advanced Energy Manufacturing Center

    Energy Technology Data Exchange (ETDEWEB)

    Kimberly Gibson; Mark Norfolk

    2012-07-30

    The program goal of the Ohio Advanced Energy Manufacturing Center (OAEMC) is to support advanced energy manufacturing and to create responsive manufacturing clusters that will support the production of advanced energy and energy-efficient products to help ensure the nation's energy and environmental security. This goal cuts across a number of existing industry segments critical to the nation's future. Many of the advanced energy businesses are starting to make the transition from technology development to commercial production. Historically, this transition from laboratory prototypes through initial production for early adopters to full production for mass markets has taken several years. Developing and implementing manufacturing technology to enable production at a price point the market will accept is a key step. Since these start-up operations are configured to advance the technology readiness of the core energy technology, they have neither the expertise nor the resources to address manufacturing readiness issues they encounter as the technology advances toward market entry. Given the economic realities of today's business environment, finding ways to accelerate this transition can make the difference between success and failure for a new product or business. The advanced energy industry touches a wide range of industry segments that are not accustomed to working together in complex supply chains to serve large markets such as automotive and construction. During its first three years, the Center has catalyzed the communication between companies and industry groups that serve the wide range of advanced energy markets. The Center has also found areas of common concern, and worked to help companies address these concerns on a segment or industry basis rather than having each company work to solve common problems individually. EWI worked with three industries through public-private partnerships to sew together disparate segments helping to promote

  2. Parkinson's Disease: The Newest Advances

    Science.gov (United States)

    Skip Navigation Bar Home Current Issue Past Issues Parkinson's Disease: The Newest Advances Past Issues / Summer 2006 ... Landis What are the risk factors for developing Parkinson's? The clearest risk factor is age. In addition, ...

  3. Parkinson's Disease: The Newest Advances

    Science.gov (United States)

    Skip Navigation Bar Home Current Issue Past Issues Parkinson's Disease: The Newest Advances Past Issues / Summer 2006 Table ... number of genes that cause or contribute to Parkinson's disease (PD), as well as potential environmental risk factors. ...

  4. SERI advanced wind turbine blades

    Science.gov (United States)

    Tangler, J.; Smith, B.; Jager, D.

    1992-02-01

    The primary goal of the Solar Energy Research Institute's (SERI) advanced wind turbine blades is to convert the kinetic energy in the wind into mechanical energy in an inexpensive and efficient manner. To accomplish this goal, advanced wind turbine blades have been developed by SERI that utilize unique airfoil technology. Performance characteristics of the advanced blades were verified through atmospheric testing on fixed-pitch, stall-regulated horizontal-axis wind turbines (HAWTs). Of the various wind turbine configurations, the stall-regulated HAWT dominates the market because of its simplicity and low cost. Results of the atmospheric tests show that the SERI advanced blades produce 10 percent to 30 percent more energy than conventional blades.

  5. Center to Advance Palliative Care

    Science.gov (United States)

    ... Discussion Forum The IPAL Project Palliative Care Leadership Centers (PCLC) Member Resources National Seminar Quick Links Certification ... a Job Manage Job Posts About About The Center to Advance Palliative Care (CAPC) is a national ...

  6. Advanced Green Micropropulsion System Project

    Data.gov (United States)

    National Aeronautics and Space Administration — Systima in collaboration with University of Washington is developing a high performance injection system for advanced green monopropellant AF-M315E micropropulsion...

  7. Advanced Cathode Electrolyzer (ACE) Project

    Data.gov (United States)

    National Aeronautics and Space Administration — The proposed innovation is a static, cathode-fed, 2000 psi, balanced-pressure Advanced Cathode Electrolyzer (ACE) based on PEM electrolysis technology. It...

  8. Advances in biomedical dosimetry

    International Nuclear Information System (INIS)

    Full text: Radiation dosimetry, the accurate determination of the absorbed dose within an irradiated body or a piece of material, is a prerequisite for all applications of ionizing radiation. This has been known since the very first radiation applications in medicine and biology, and increasing efforts are being made by radiation researchers to develop more reliable, effective and safe instruments, and to further improve dosimetric accuracy for all types of radiation used. Development of new techniques and instrumentation was particularly fast in the field of both medical diagnostic and therapeutic radiology. Thus, in Paris in October the IAEA held the latest symposium in its continuing series on dosimetry in medicine and biology. The last one was held in Vienna in 1975. High-quality dosimetry is obviously of great importance for human health, whether the objectives lie in the prevention and control of risks associated with the nuclear industry, in medical uses of radioactive substances or X-ray beams for diagnostic purposes, or in the application of photon, electron or neutron beams in radiotherapy. The symposium dealt with the following subjects: General aspects of dosimetry; Special physical and biomedical aspects; Determination of absorbed dose; Standardization and calibration of dosimetric systems; and Development of dosimetric systems. The forty or so papers presented and the discussions that followed them brought out a certain number of dominant themes, among which three deserve particular mention. - The recent generalization of the International System of Units having prompted a fundamental reassessment of the dosimetric quantities to be considered in calibrating measuring instruments, various proposals were advanced by the representatives of national metrology laboratories to replace the quantity 'exposure' (SI unit = coulomb/kg) by 'Kerma' or 'absorbed dose' (unit joule/kg, the special name of which is 'gray'), this latter being closer to the practical

  9. ADVANCED HYBRID PARTICULATE COLLECTOR

    Energy Technology Data Exchange (ETDEWEB)

    Ye Zhuang; Stanley J. Miller; Michelle R. Olderbak; Rich Gebert

    2001-12-01

    A new concept in particulate control, called an advanced hybrid particulate collector (AHPC), is being developed under funding from the U.S. Department of Energy. The AHPC combines the best features of electrostatic precipitators (ESPs) and baghouses in an entirely novel manner. The AHPC concept combines fabric filtration and electrostatic precipitation in the same housing, providing major synergism between the two methods, both in the particulate collection step and in transfer of dust to the hopper. The AHPC provides ultrahigh collection efficiency, overcoming the problem of excessive fine-particle emissions with conventional ESPs, and solves the problem of reentrainment and re-collection of dust in conventional baghouses. Phase I of the development effort consisted of design, construction, and testing of a 5.7-m{sup 3}/min (200-acfm) working AHPC model. Results from both 8-hr parametric tests and 100-hr proof-of-concept tests with two different coals demonstrated excellent operability and greater than 99.99% fine-particle collection efficiency. Since all of the developmental goals of Phase I were met, the approach was scaled up in Phase II to a size of 255 m{sup 3}/min (9000 acfm) (equivalent in size to 2.5 MW) and was installed on a slipstream at the Big Stone Power Plant. For Phase II, the AHPC at Big Stone Power Plant was operated continuously from late July 1999 until mid-December 1999. The Phase II results were highly successful in that ultrahigh particle collection efficiency was achieved, pressure drop was well controlled, and system operability was excellent. For Phase III, the AHPC was modified into a more compact configuration, and components were installed that were closer to what would be used in a full-scale commercial design. The modified AHPC was operated from April to July 2000. While operational results were acceptable during this time, inspection of bags in the summer of 2000 revealed some membrane damage to the fabric that appeared to be

  10. Advanced Microturbine Systems

    Energy Technology Data Exchange (ETDEWEB)

    Rosfjord, T; Tredway, W; Chen, A; Mulugeta, J; Bhatia, T

    2008-12-31

    In July 2000, the United Technologies Research Center (UTRC) was one of five recipients of a US Department of Energy contract under the Advanced Microturbine System (AMS) program managed by the Office of Distributed Energy (DE). The AMS program resulted from several government-industry workshops that recognized that microturbine systems could play an important role in improving customer choice and value for electrical power. That is, the group believed that electrical power could be delivered to customers more efficiently and reliably than the grid if an effective distributed energy strategy was followed. Further, the production of this distributed power would be accomplished with less undesirable pollutants of nitric oxides (NOx) unburned hydrocarbons (UHC), and carbon monoxide (CO). In 2000, the electrical grid delivered energy to US customers at a national average of approximately 32% efficiency. This value reflects a wide range of powerplants, but is dominated by older, coal burning stations that provide approximately 50% of US electrical power. The grid efficiency is also affected by transmission and distribution (T&D) line losses that can be significant during peak power usage. In some locations this loss is estimated to be 15%. Load pockets can also be so constrained that sufficient power cannot be transmitted without requiring the installation of new wires. New T&D can be very expensive and challenging as it is often required in populated regions that do not want above ground wires. While historically grid reliability has satisfied most customers, increasing electronic transactions and the computer-controlled processes of the 'digital economy' demand higher reliability. For them, power outages can be very costly because of transaction, work-in-progress, or perishable commodity losses. Powerplants that produce the grid electrical power emit significant levels of undesirable NOx, UHC, and CO pollutants. The level of emission is quoted as either a

  11. ADVANCED WORKER PROTECTION SYSTEM

    International Nuclear Information System (INIS)

    From 1993 to 2000, OSS worked under a cost share contract from the Department of Energy (DOE) to develop an Advanced Worker Protection System (AWPS). The AWPS is a protective ensemble that provides the user with both breathing air and cooling for a NIOSH-rated duration of two hours. The ensemble consists of a liquid air based backpack, a Liquid Cooling Garment (LCG), and an outer protective garment. The AWPS project was divided into two phases. During Phase 1, OSS developed and tested a full-scale prototype AWPS. The testing showed that workers using the AWPS could work twice as long as workers using a standard SCBA. The testing also provided performance data on the AWPS in different environments that was used during Phase 2 to optimize the design. During Phase 1, OSS also performed a life-cycle cost analysis on a representative clean up effort. The analysis indicated that the AWPS could save the DOE millions of dollars on D and D activities and improve the health and safety of their workers. During Phase 2, OSS worked to optimize the AWPS design to increase system reliability, to improve system performance and comfort, and to reduce the backpack weight and manufacturing costs. To support this design effort, OSS developed and tested several different generations of prototype units. Two separate successful evaluations of the ensemble were performed by the International Union of Operation Engineers (IUOE). The results of these evaluations were used to drive the design. During Phase 2, OSS also pursued certifying the AWPS with the applicable government agencies. The initial intent during Phase 2 was to finalize the design and then to certify the system. OSS and Scott Health and Safety Products teamed to optimize the AWPS design and then certify the system with the National Institute of Occupational Health and Safety (NIOSH). Unfortunately, technical and programmatic difficulties prevented us from obtaining NIOSH certification. Despite the inability of NIOSH to certify

  12. ADVANCED CUTTINGS TRANSPORT STUDY

    Energy Technology Data Exchange (ETDEWEB)

    Stefan Miska; Troy Reed; Ergun Kuru

    2004-09-30

    The Advanced Cuttings Transport Study (ACTS) was a 5-year JIP project undertaken at the University of Tulsa (TU). The project was sponsored by the U.S. Department of Energy (DOE) and JIP member companies. The objectives of the project were: (1) to develop and construct a new research facility that would allow three-phase (gas, liquid and cuttings) flow experiments under ambient and EPET (elevated pressure and temperature) conditions, and at different angle of inclinations and drill pipe rotation speeds; (2) to conduct experiments and develop a data base for the industry and academia; and (3) to develop mechanistic models for optimization of drilling hydraulics and cuttings transport. This project consisted of research studies, flow loop construction and instrumentation development. Following a one-year period for basic flow loop construction, a proposal was submitted by TU to the DOE for a five-year project that was organized in such a manner as to provide a logical progression of research experiments as well as additions to the basic flow loop. The flow loop additions and improvements included: (1) elevated temperature capability; (2) two-phase (gas and liquid, foam etc.) capability; (3) cuttings injection and removal system; (4) drill pipe rotation system; and (5) drilling section elevation system. In parallel with the flow loop construction, hydraulics and cuttings transport studies were preformed using drilling foams and aerated muds. In addition, hydraulics and rheology of synthetic drilling fluids were investigated. The studies were performed under ambient and EPET conditions. The effects of temperature and pressure on the hydraulics and cuttings transport were investigated. Mechanistic models were developed to predict frictional pressure loss and cuttings transport in horizontal and near-horizontal configurations. Model predictions were compared with the measured data. Predominantly, model predictions show satisfactory agreements with the measured data. As a

  13. ADVANCED WORKER PROTECTION SYSTEM

    Energy Technology Data Exchange (ETDEWEB)

    Judson Hedgehock

    2001-03-16

    From 1993 to 2000, OSS worked under a cost share contract from the Department of Energy (DOE) to develop an Advanced Worker Protection System (AWPS). The AWPS is a protective ensemble that provides the user with both breathing air and cooling for a NIOSH-rated duration of two hours. The ensemble consists of a liquid air based backpack, a Liquid Cooling Garment (LCG), and an outer protective garment. The AWPS project was divided into two phases. During Phase 1, OSS developed and tested a full-scale prototype AWPS. The testing showed that workers using the AWPS could work twice as long as workers using a standard SCBA. The testing also provided performance data on the AWPS in different environments that was used during Phase 2 to optimize the design. During Phase 1, OSS also performed a life-cycle cost analysis on a representative clean up effort. The analysis indicated that the AWPS could save the DOE millions of dollars on D and D activities and improve the health and safety of their workers. During Phase 2, OSS worked to optimize the AWPS design to increase system reliability, to improve system performance and comfort, and to reduce the backpack weight and manufacturing costs. To support this design effort, OSS developed and tested several different generations of prototype units. Two separate successful evaluations of the ensemble were performed by the International Union of Operation Engineers (IUOE). The results of these evaluations were used to drive the design. During Phase 2, OSS also pursued certifying the AWPS with the applicable government agencies. The initial intent during Phase 2 was to finalize the design and then to certify the system. OSS and Scott Health and Safety Products teamed to optimize the AWPS design and then certify the system with the National Institute of Occupational Health and Safety (NIOSH). Unfortunately, technical and programmatic difficulties prevented us from obtaining NIOSH certification. Despite the inability of NIOSH to certify

  14. Advanced Algal Systems Fact Sheet

    Energy Technology Data Exchange (ETDEWEB)

    None

    2016-06-01

    Research and development (R&D) on advanced algal biofuels and bioproducts presents an opportunity to sustainably expand biomass resource potential in the United States. The Bioenergy Technologies Office’s (BETO’s) Advanced Algal Systems Program is carrying out a long-term, applied R&D strategy to lower the costs of algal biofuel production by working with partners to develop revolutionary technologies and conduct crosscutting analyses to better understand the potential

  15. Advances in FIV vaccine technology

    OpenAIRE

    Uhl, Elizabeth W.; Martin, Marcus; Coleman, James K.; Yamamoto, Janet K

    2008-01-01

    Advances in vaccine technology are occurring in the molecular techniques used to develop vaccines and in the assessment of vaccine efficacy, allowing more complete characterization of vaccine-induced immunity correlating to protection. FIV vaccine development has closely mirrored and occasionally surpassed the development of HIV-1 vaccine, leading to first licensed technology. This review will discuss technological advances in vaccine designs, challenge infection assessment, and characterizat...

  16. Recent advances in pediatric uroradiology

    OpenAIRE

    Reddy, Pramod P.

    2007-01-01

    Pediatric Urology is a surgical subspecialty that is very dependent upon radiographic imaging as the majority of the genitourinary (GU) tract is internally located. Technological advances in various imaging modalities (e.g. ultrasonography, nuclear medicine, CT and MRI) have aided in our ability to visualize and evaluate the functionality of the GU tract, enabling the diagnosis of various disease processes that affect the genitourinary system. Collectively the advances in uro-radiology have i...

  17. SENIOR STAFF ADVANCEMENT COMMITTEE (SSAC)

    CERN Multimedia

    2000-01-01

    Composition and mandateThe Senior Staff Advancement Committee is composed of members nominated ad persona by the Director-General.The Committee examines proposals from Divisions concerning promotions to grade 13 in Career Path IX, changes of career path to Career Path IX and advancements to the exceptional grade in Career path VIII.The Director-General may consult the Committee on any matter related to senior staff careers.The Committee makes its recommendations to the Director-General.

  18. Advanced border monitoring sensor system

    Science.gov (United States)

    Knobler, Ronald A.; Winston, Mark A.

    2008-04-01

    McQ has developed an advanced sensor system tailored for border monitoring that has been delivered as part of the SBInet program for the Department of Homeland Security (DHS). Technology developments that enhance a broad range of features are presented in this paper, which address the overall goal of the system to improving unattended ground sensor system capabilities for border monitoring applications. Specifically, this paper addresses a system definition, communications architecture, advanced signal processing to classify targets, and distributed sensor fusion processing.

  19. Energy Storage (II): Developing Advanced Technologies

    Science.gov (United States)

    Robinson, Arthur L

    1974-01-01

    Energy storage, considered by some scientists to be the best technological and economic advancement after advanced nuclear power, still rates only modest funding for research concerning the development of advanced technologies. (PEB)

  20. Advanced Manufacture of Reflectors

    Energy Technology Data Exchange (ETDEWEB)

    Angel, Roger [University of Arizona

    2014-12-17

    The main project objective has been to develop an advanced gravity sag method for molding large glass solar reflectors with either line or point focus, and with long or short focal length. The method involves taking standard sized squares of glass, 1.65 m x 1.65 m, and shaping them by gravity sag into precision steel molds. The method is designed for high volume manufacture when incorporated into a production line with separate pre-heating and cooling. The performance objectives for the self-supporting glass mirrors made by this project include mirror optical accuracy of 2 mrad root mean square (RMS), requiring surface slope errors <1 mrad rms, a target not met by current production of solar reflectors. Our objective also included development of new methods for rapidly shaping glass mirrors and coating them for higher reflectivity and soil resistance. Reflectivity of 95% for a glass mirror with anti-soil coating was targeted, compared to the present ~94% with no anti-soil coating. Our mirror cost objective is ~$20/m2 in 2020, a significant reduction compared to the present ~$35/m2 for solar trough mirrors produced for trough solar plants. During the first year a custom batch furnace was built to develop the method with high power radiative heating to simulate transfer of glass into a hot slumping zone in a production line. To preserve the original high polish of the float glass on both front and back surfaces, as required for a second surface mirror, the mold surface is machined to the required shape as grooves which intersect the glass at cusps, reducing the mold contact area to significantly less than 1%. The mold surface is gold-plated to reflect thermal radiation. Optical metrology of glass replicas made with the system has been carried out with a novel, custom-built test system. This test provides collimated, vertically-oriented parallel beams from a linear array of co-aligned lasers translated in a perpendicular direction across the reflector. Deviations of

  1. NATO Advanced Study Institute on Advanced Physical Oceanographic Numerical Modelling

    CERN Document Server

    1986-01-01

    This book is a direct result of the NATO Advanced Study Institute held in Banyuls-sur-mer, France, June 1985. The Institute had the same title as this book. It was held at Laboratoire Arago. Eighty lecturers and students from almost all NATO countries attended. The purpose was to review the state of the art of physical oceanographic numerical modelling including the parameterization of physical processes. This book represents a cross-section of the lectures presented at the ASI. It covers elementary mathematical aspects through large scale practical aspects of ocean circulation calculations. It does not encompass every facet of the science of oceanographic modelling. We have, however, captured most of the essence of mesoscale and large-scale ocean modelling for blue water and shallow seas. There have been considerable advances in modelling coastal circulation which are not included. The methods section does not include important material on phase and group velocity errors, selection of grid structures, advanc...

  2. Oncology Advanced Practitioners Bring Advanced Community Oncology Care.

    Science.gov (United States)

    Vogel, Wendy H

    2016-01-01

    Oncology care is becoming increasingly complex. The interprofessional team concept of care is necessary to meet projected oncology professional shortages, as well as to provide superior oncology care. The oncology advanced practitioner (AP) is a licensed health care professional who has completed advanced training in nursing or pharmacy or has completed training as a physician assistant. Oncology APs increase practice productivity and efficiency. Proven to be cost effective, APs may perform varied roles in an oncology practice. Integrating an AP into an oncology practice requires forethought given to the type of collaborative model desired, role expectations, scheduling, training, and mentoring. PMID:27249776

  3. Advances in heavy water reactors

    International Nuclear Information System (INIS)

    The current IAEA programme in advanced nuclear power technology promotes technical information exchange between Member States with major development programmes. The Technical Committee Meeting (TCM) on Advances in Heavy Water Reactors was organized by the IAEA in the framework of the activities of the International Working Group on Advanced Technologies for Water Cooled Reactors (IWGATWR) and hosted by the Atomic Energy of Canada Limited. Sixty-five participants from nine countries (Canada, Czech Republic, India, German, Japan, Republic of Korea, Pakistan, Romania and USA) and the IAEA attended the TCM. Thirty-four papers were presented and discussed in five sessions. A separate abstract was prepared for each of these papers. All recommendations which were addressed by the participants of the Technical Committee meeting to the IWGATWR have been submitted to the 5th IWGATWR meeting in September 1993. They were reviewed and used as input for the preparation of the IAEA programme in the area of advanced water cooled reactors. This TCM was mainly oriented towards advances in HWRs and on projects which are now in the design process and under discussion. Refs, figs and tabs

  4. Nanotechnological Basis for Advanced Sensors

    CERN Document Server

    Reithmaier, Johann Peter; Kulisch, Wilhelm; Popov, Cyril; Petkov, Plamen

    2011-01-01

    Bringing together experts from 15 countries, this book is based on the lectures and contributions of the NATO Advanced Study Institute on “Nanotechnological Basis for Advanced Sensors” held in Sozopol, Bulgaria, 30 May - 11 June, 2010. It gives a broad overview on this topic, and includes articles on: techniques for preparation and characterization of sensor materials; different types of nanoscaled materials for sensor applications, addressing both their structure (nanoparticles, nanocomposites, nanostructured films, etc.) and chemical nature (carbon-based, oxides, glasses, etc.); and on advanced sensors that exploit nanoscience and nanotechnology. In addition, the volume represents an interdisciplinary approach with authors coming from diverse fields such as physics, chemistry, engineering, materials science and biology. A particular strength of the book is its combination of longer papers, introducing the basic knowledge on a certain topic, and brief contributions highlighting special types of sensors a...

  5. Advanced Control of Turbofan Engines

    CERN Document Server

    Richter, Hanz

    2012-01-01

    Advanced Control of Turbofan Engines describes the operational performance requirements of turbofan (commercial)engines from a controls systems perspective, covering industry-standard methods and research-edge advances. This book allows the reader to design controllers and produce realistic simulations using public-domain software like CMAPSS: Commercial Modular Aero-Propulsion System Simulation, whose versions are released to the public by NASA. The scope of the book is centered on the design of thrust controllers for both steady flight and transient maneuvers. Classical control theory is not dwelled on, but instead an introduction to general undergraduate control techniques is provided. This book also: Develops a thorough understanding of the challenges associated with engine operability from a control systems perspective, describing performance demands and operational constraints into the framework and language of modern control theory Presents solid theoretical support for classical and advanced engine co...

  6. Optical properties of advanced materials

    CERN Document Server

    Kajikawa, Kotaro

    2013-01-01

    In the last decade, optically functionalized materials have developed rapidly, from bulk matters to structured forms. Now we have a rich variety of attractive advanced materials. They are applied to optical and electrical devices that support the information communication technology in the mid 21-th century. Accordingly, it is quite important to have a broad knowledge of the optical properties of advanced materials for students, scientists and engineers working in optics and related fields. This book is designed to teach fundamental optical properties of such advanced materials effectively. These materials have their own peculiarities which are very interesting in modern optical physics and also for applications because the concepts of optical properties are quite different from those in conventional optical materials. Hence each chapter starts to review the basic concepts of the materials briefly and proceeds to the practical use. The important topics covered in this book include:  quantum structures of sem...

  7. The Advanced LIGO Photon Calibrators

    CERN Document Server

    Karki, S; Kandhasamy, S; Abbott, B P; Abbott, T D; Anders, E H; Berliner, J; Betzwieser, J; Daveloza, H P; Cahillane, C; Canete, L; Conley, C; Gleason, J R; Goetz, E; Kissel, J S; Izumi, K; Mendell, G; Quetschke, V; Rodruck, M; Sachdev, S; Sadecki, T; Schwinberg, P B; Sottile, A; Wade, M; Weinstein, A J; West, M; Savage, R L

    2016-01-01

    The two interferometers of the Laser Interferometry Gravitaional-wave Observatory (LIGO) recently detected gravitational waves from the mergers of binary black hole systems. Accurate calibration of the output of these detectors was crucial for the observation of these events, and the extraction of parameters of the sources. The principal tools used to calibrate the responses of the second-generation (Advanced) LIGO detectors to gravitational waves are systems based on radiation pressure and referred to as Photon Calibrators. These systems, which were completely redesigned for Advanced LIGO, include several significant upgrades that enable them to meet the calibration requirements of second-generation gravitational wave detectors in the new era of gravitational-wave astronomy. We report on the design, implementation, and operation of these Advanced LIGO Photon Calibrators that are currently providing fiducial displacements on the order of $10^{-18}$ m/$\\sqrt{\\textrm{Hz}}$ with accuracy and precision of better ...

  8. Advances in Home Photo Printing

    Institute of Scientific and Technical Information of China (English)

    Qian Lin; Brian Atkins; Huitao Luo

    2004-01-01

    With digital camera adoptions going main stream, consumers capture a record number of photos.Currently, the majority of the digital photos are printed at home. One of the key enablers of this transformation is the advancement of home photo printing technologies. In the past few years, inkjet printing technologies have continued to deliver smaller drop size, larger number of inks, and longer-lasting prints. In the mean time, advanced image processing automatically enhances captured digital photos while being printed. The combination of the above two forces has closed the gap between the home photo prints and AgX prints. It will give an overview of the home photo printing market and technology trends, and discuss major advancements in automatic image processing.

  9. Translational research on advanced therapies

    Directory of Open Access Journals (Sweden)

    Filippo Belardelli

    2011-01-01

    Full Text Available Fostering translational research of advanced therapies has become a major priority of both scientific community and national governments. Advanced therapy medicinal products (ATMP are a new medicinal product category comprising gene therapy and cell-based medicinal products as well as tissue engineered medicinal products. ATMP development opens novel avenues for therapeutic approaches in numerous diseases, including cancer and neurodegenerative and cardiovascular diseases. However, there are important bottlenecks for their development due to the complexity of the regulatory framework, the high costs and the needs for good manufacturing practice (GMP facilities and new end-points for clinical experimentation. Thus, a strategic cooperation between different stakeholders (academia, industry and experts in regulatory issues is strongly needed. Recently, a great importance has been given to research infrastructures dedicated to foster translational medicine of advanced therapies. Some ongoing European initiatives in this field are presented and their potential impact is discussed.

  10. Dementia, death and advance directives.

    Science.gov (United States)

    Wolff, Jonathan

    2012-10-01

    This article considers the ethics of advance directives, especially in relation to conditions such as dementia. For some choices, such as over whether one's life should end at home or in a hospice, advance directives can be very enlightened and helpful. For others, such as those to end the life of an autonomous subject, against their will, have no moral appeal and would rightly be ignored. In a wide range of intermediate cases, given our typical lack of insight into how changes in our health condition will affect us in other ways, we should be very cautious indeed in promoting the use of advance directives in end-of-life decisions, at least where a reasonable quality of life remains. There may be some reasons for giving priority to the earlier autonomous self over a later, contented but non-autonomous self, but these reasons seem far from compelling. PMID:23079306

  11. All Students Need Advanced Mathematics. Math Works

    Science.gov (United States)

    Achieve, Inc., 2013

    2013-01-01

    This fact sheet explains that to thrive in today's world, all students will need to graduate with very strong math skills. That can only mean one thing: advanced math courses are now essential math courses. Highlights of this paper include: (1) Advanced math equals college success; (2) Advanced math equals career opportunity; and (3) Advanced math…

  12. Principles of modern radar advanced techniques

    CERN Document Server

    Melvin, William

    2012-01-01

    Principles of Modern Radar: Advanced Techniques is a professional reference for practicing engineers that provides a stepping stone to advanced practice with in-depth discussions of the most commonly used advanced techniques for radar design. It will also serve advanced radar academic and training courses with a complete set of problems for students as well as solutions for instructors.

  13. Advances in automotive control 2001

    Energy Technology Data Exchange (ETDEWEB)

    Kiencke, U.; Gissinger, G.L. (eds.)

    2001-07-01

    The aim of the 3rd IFAC Workshop 'Advances in Automotive Control', held in Karlsruhe, Germany on 28-30 March 2001, was to discuss the latest advances in relation to motor vehicles. The increase in road traffic in the 20th century was a major problem, and one of the challenges of the 21st century will be to improve driving safety and comfort. The proceedings covers: driveline control; driveline modelling; vehicle dynamics; electronic architecture; intelligent components; engine control; diagnostics; subsystems; engine modelling; and modelling of combustion and turbo-charging. 28 of the papers are abstracted here.

  14. Recent advances in nuclear cardiology

    DEFF Research Database (Denmark)

    Gutte, H.; Petersen, C. Leth; Kjaer, A.;

    2008-01-01

    Nuclear cardiology is an essential part of functional, non-invasive, cardiac imaging. Significant advances have been made in nuclear cardiology since planar (201)thallium ((201)TI) scintigraphy was introduced for the evaluation of left ventricular (LV) perfusion nearly 40 years ago. The use......-coronary cardiac diseases. The advances in nuclear cardiology are discussed under the four headlines of: 1) myocardial perfusion, 2) cardiac performance including LV and right ventricular (RV) function, 3) myocardial metabolism, and 4) experimental nuclear cardiology Udgivelsesdato: 2008/6...

  15. Advanced solar thermal receiver technology

    Science.gov (United States)

    Kudirka, A. A.; Leibowitz, L. P.

    1980-01-01

    Development of advanced receiver technology for solar thermal receivers designed for electric power generation or for industrial applications, such as fuels and chemical production or industrial process heat, is described. The development of this technology is focused on receivers that operate from 1000 F to 3000 F and above. Development strategy is mapped in terms of application requirements, and the related system and technical requirements. Receiver performance requirements and current development efforts are covered for five classes of receiver applications: high temperature, advanced Brayton, Stirling, and Rankine cycle engines, and fuels and chemicals.

  16. Overview of advanced fuel fusion

    International Nuclear Information System (INIS)

    The status and issues related to the development of advanced fuel fusion are discussed. D-3He is a key advanced fuel since it has the potential of igniting in a variety of confinement concepts. However, to obtain a plentiful source of 3He, either lunar mining or breeding becomes necessary. Highly non-Maxwellian plasmas, such as might occur in beam-beam fusion concepts, are necessary to address fuels like p-11B which have the added advantages of a more aneutronic character and plentiful fuel supply. Such plasmas appear very difficult to achieve but several possible approaches such as electrostatic confinement are noted. 52 refs., 13 figs, 5 tabs

  17. Advances in high temperature chemistry

    CERN Document Server

    Eyring, Leroy

    1969-01-01

    Advances in High Temperature Chemistry, Volume 2 covers the advances in the knowledge of the high temperature behavior of materials and the complex and unfamiliar characteristics of matter at high temperature. The book discusses the dissociation energies and free energy functions of gaseous monoxides; the matrix-isolation technique applied to high temperature molecules; and the main features, the techniques for the production, detection, and diagnosis, and the applications of molecular beams in high temperatures. The text also describes the chemical research in streaming thermal plasmas, as w

  18. Advanced defect and metrology solutions

    Science.gov (United States)

    Novak, Erik

    2014-05-01

    Cost, weight, performance, and lifetime requirements for precision components used throughout the aerospace and defense industries are driving innovative mechanical designs, manufacturing processes and use of new materials. In turn, these advanced components typically require tighter dimensional and surface tolerances to function as designed. Scratch testers, microscope-based systems, and other traditional metrology systems are inadequate for roughness, small-scale geometry, and defect determination on many of these parts. This talk will examine the advantages and disadvantages of some of the new technologies developed to provide more robust, versatile, and sensitive measurements of precision components for advanced manufacturing environments.

  19. Dementia, death and advance directives.

    OpenAIRE

    Wolff, J.

    2012-01-01

    This article considers the ethics of advance directives, especially in relation to conditions such as dementia. For some choices, such as over whether one's life should end at home or in a hospice, advance directives can be very enlightened and helpful. For others, such as those to end the life of an autonomous subject, against their will, have no moral appeal and would rightly be ignored. In a wide range of intermediate cases, given our typical lack of insight into how changes in our health ...

  20. Palliative care in advanced dementia.

    Science.gov (United States)

    Merel, Susan E; Merel, Susan; DeMers, Shaune; Vig, Elizabeth

    2014-08-01

    Because neurodegenerative dementias are progressive and ultimately fatal, a palliative approach focusing on comfort, quality of life, and family support can have benefits for patients, families, and the health system. Elements of a palliative approach include discussion of prognosis and goals of care, completion of advance directives, and a thoughtful approach to common complications of advanced dementia. Physicians caring for patients with dementia should formulate a plan for end-of-life care in partnership with patients, families, and caregivers, and be prepared to manage common symptoms at the end of life in dementia, including pain and delirium. PMID:25037291

  1. Image restoration fundamentals and advances

    CERN Document Server

    Gunturk, Bahadir Kursat

    2012-01-01

    Image Restoration: Fundamentals and Advances responds to the need to update most existing references on the subject, many of which were published decades ago. Providing a broad overview of image restoration, this book explores breakthroughs in related algorithm development and their role in supporting real-world applications associated with various scientific and engineering fields. These include astronomical imaging, photo editing, and medical imaging, to name just a few. The book examines how such advances can also lead to novel insights into the fundamental properties of image sources. Addr

  2. Advanced Maya texturing and lighting

    CERN Document Server

    Lanier, Lee

    2015-01-01

    Level up your skills with powerful texturing and lighting techniques Advanced Maya Texturing and Lighting, Third Edition leads you through the latest advanced techniques for adding realistic detail to your models. This new edition is up-to-date with the latest Maya texturing, lighting, and rendering features, including an exploration of the Node Editor, new Maya utility nodes and expanded coverage of mental ray shaders, and render settings. The proven tutorials are culled from real-world experience and refined to give you the ultimate in practical skills. You'll learn workflow t

  3. Seismic isolation for Advanced LIGO

    CERN Document Server

    Abbott, R; Allen, G; Cowley, S; Daw, E; Debra, D; Giaime, J; Hammond, G; Hammond, M; Hardham, C; How, J; Hua, W; Johnson, W; Lantz, B; Mason, K; Mittleman, R; Nichol, J; Richman, S; Rollins, J; Shoemaker, D; Stapfer, G; Stebbins, R

    2002-01-01

    The baseline design concept for a seismic isolation component of the proposed 'Advanced LIGO' detector upgrade has been developed with proof-of-principle experiments and computer models. It consists of a two-stage in-vacuum active isolation platform that is supported by an external hydraulic actuation stage. Construction is underway for prototype testing of a full-scale preliminary design.

  4. Recent Advances in Microflow Photochemistry

    Directory of Open Access Journals (Sweden)

    Oksana Shvydkiv

    2011-09-01

    Full Text Available This review summarizes recent advances in microflow photochemical technologies and transformations. The portfolio of reactions comprises homogeneous and heterogeneous types, among them photoadditions, photorearrangements, photoreductions, photodecarboxylations, photooxygenations and photochlorinations. While microflow photochemistry is most commonly employed as a micro-scale synthesis tool, scale-up and technical production processes have already been developed.

  5. ADVANCED GAS TURBINE SYSTEMS RESEARCH

    Energy Technology Data Exchange (ETDEWEB)

    Unknown

    2002-04-01

    The activities of the Advanced Gas Turbine Systems Research (AGTSR) program for this reporting period are described in this quarterly report. The report is divided into discussions of Membership, Administration, Technology Transfer (Workshop/Education), Research and Miscellaneous Related Activity. Items worthy of note are presented in extended bullet format following the appropriate heading.

  6. ADVANCED GAS TURBINE SYSTEMS RESEARCH

    Energy Technology Data Exchange (ETDEWEB)

    Unknown

    2002-02-01

    The activities of the Advanced Gas Turbine Systems Research (AGTSR) program for this reporting period are described in this quarterly report. The report is divided into discussions of Membership, Administration, Technology Transfer (Workshop/Education), Research and Miscellaneous Related Activity. Items worthy of note are presented in extended bullet format following the appropriate heading.

  7. Seismic isolation for Advanced LIGO

    International Nuclear Information System (INIS)

    The baseline design concept for a seismic isolation component of the proposed 'Advanced LIGO' detector upgrade has been developed with proof-of-principle experiments and computer models. It consists of a two-stage in-vacuum active isolation platform that is supported by an external hydraulic actuation stage. Construction is underway for prototype testing of a full-scale preliminary design

  8. Sorafenib in advanced hepatocellular carcinoma

    DEFF Research Database (Denmark)

    Køstner, Anne Helene; Sørensen, M; Olesen, René Krøjgaard;

    2013-01-01

    Advanced HCC is a clinical challenge with limited treatment options. The multikinase inhibitor sorafenib is the first and only agent showing a survival benefit in these patients. In this study we evaluate the efficacy and tolerability of sorafenib in an unselected patient population. Furthermore we...

  9. Trends in advanced wastewater treatment

    DEFF Research Database (Denmark)

    Henze, M.

    1997-01-01

    The paper examines the present trends within wastewater handling and treatment. The trend is towards the extremes, either local low-tech treatment or centralized advanced treatment plants. The composition of the wastewater will change and it will be regarded as a resource. There will be more...

  10. Advanced Fuels Campaign 2012 Accomplishments

    Energy Technology Data Exchange (ETDEWEB)

    Not Listed

    2012-11-01

    The Advanced Fuels Campaign (AFC) under the Fuel Cycle Research and Development (FCRD) program is responsible for developing fuels technologies to support the various fuel cycle options defined in the DOE Nuclear Energy Research and Development Roadmap, Report to Congress, April 2010. The fiscal year 2012 (FY 2012) accomplishments are highlighted below. Kemal Pasamehmetoglu is the National Technical Director for AFC.

  11. Advances in transport phenomena 2011

    CERN Document Server

    2014-01-01

    This new volume of the annual review “Advances in Transport Phenomena” series contains three in-depth review articles on the microfluidic fabrication of vesicles, the dielectrophoresis field-flow fractionation for continuous-flow separation of particles and cells in microfluidic devices, and the thermodynamic analysis and optimization of heat exchangers, respectively.

  12. Advanced fusion concepts project summaries

    International Nuclear Information System (INIS)

    The activities of all the projects supported by the Advanced Fusion Concepts Branch of the Office of Fusion Energy, DOE, are described. These descriptions are project summaries of each of the individual projects, and contain title, persons responsible, funding, purpose, approach, recent progress, future plans, planned milestones, graduate students and other staff, and recent publications

  13. Advances in Mobile Data Communications

    Institute of Scientific and Technical Information of China (English)

    Sean Cai; Li Mo

    2011-01-01

    This special issue of ZTE Communications focuses on recent advances in mobile data communications for the ICT and telecommunications industries. The ever-increasing amount of mobile data traffic has beenthe subject of many studies. This research area is widely applicable to contemporary technology and network optimization techniques.

  14. Advancing Diversity in Higher Education

    Science.gov (United States)

    Turner, Caroline S.

    2013-01-01

    This special section of the "Journal of Diversity in Higher Education" ("JDHE") on "Advancing Diversity in Higher Education" emerged from the 2012 Association for the Study of Higher Education Council on Ethnic Participation (ASHE-CEP) Pre-Conference Forum. CEP, a standing committee of ASHE, partnered with the…

  15. Handbook of Advanced Multilevel Analysis

    CERN Document Server

    Hox, Joop

    2010-01-01

    This new handbook is the definitive resource on advanced topics related to multilevel analysis. The editors have assembled the top minds in the field to address the latest applications of multilevel modeling as well as the specific difficulties and methodological problems that are becoming more common as more complicated models are developed.

  16. Advances in PCB decontamination technologies

    International Nuclear Information System (INIS)

    Since 1985 several million kilograms of PCB equipment and millions of litres of PCB contaminated oil have been processed in Canada for reduction of PCB concentrations below government guidelines. Advances in extraction and metal recovery from electrical equipment, chemical dechlorination and distillation of PCB-contaminated oils were the significant technological options utilized. For example, using the Decontaksolv technology owners of PCB equipment in Canada have decontaminated three million kilograms of electrical equipment, which resulted in the reintegration of 2.7 million kilograms of useful metals (steel, copper, aluminium) into the economic circuit. The equipment decontaminated included transformers, electromagnets, relays, radiators, circuit breakers, tanks, pipes, valves, and drums. The most recent advances in this technology include improvements that makes the economical processing of capacitors, possible. Chemical dechlorination has virtually eliminated PCB-contaminated oils which are normally present in large transformers, to the point where some service companies have curtailed or discontinued their oil decontamination activities in Canada. Recent advances in this technology center around techniques for the decontamination of waste hydrocarbons, and to a lesser extent, dielectric fluids. Two example projects to illustrate recent advances have been briefly described

  17. Modern Advances in Ablative TPS

    Science.gov (United States)

    Venkatapathy, Ethiraj

    2013-01-01

    Topics covered include: Physics of Hypersonic Flow and TPS Considerations. Destinations, Missions and Requirements. State of the Art Thermal Protection Systems Capabilities. Modern Advances in Ablative TPS. Entry Systems Concepts. Flexible TPS for Hypersonic Inflatable Aerodynamic Decelerators. Conformal TPS for Rigid Aeroshell. 3-D Woven TPS for Extreme Entry Environment. Multi-functional Carbon Fabric for Mechanically Deployable.

  18. FTIR characterization of advanced materials

    Science.gov (United States)

    Young, P. R.; Chang, A. C.

    1986-01-01

    This paper surveys the application of Fourier transform infrared spectroscopy to the characterization of advanced materials. FTIR sampling techniques including internal and external reflectance and photoacoustic spectroscopy are discussed. Representative examples from the literature of the analysis of resins, fibers, prepregs and composites are reviewed. A discussion of several promising specialized FTIR techniques is also presented.

  19. Advances in alimentary tract imaging

    OpenAIRE

    Maglinte, Dean DT; Sandrasegaran, Kumaresan; Tann, Mark

    2006-01-01

    Advances in imaging techniques are changing the way radiologists undertake imaging of the gastrointestinal tract and their ability to answer questions posed by surgeons. In this paper we discuss the technological improvements of imaging studies that have occurred in the last few years and how these help to better diagnosing alimentary tract disease.

  20. Advances in luminescence instrument systems

    DEFF Research Database (Denmark)

    Bøtter-Jensen, L.; Bulur, E.; Duller, G.A.T.;

    2000-01-01

    We report on recent advances in the development of luminescence measurement systems and techniques at Riso. These include: (1) optical stimulation units based on new-generation powerful blue light (470 nm) emitting diodes providing up to 28 mW/cm(2) for OSL measurements; (2) an infrared (830 nm...

  1. Recent advances in steroid radioimmunoassay

    International Nuclear Information System (INIS)

    The advances since 1974 in the techniques of measuring steroid molecules by radioimmunoassay are reviewed in this paper. They are considered under the following headings: preparation and use of antisera; preparation and use of tracers; preparation of biological samples before assay; dispensing of the reagents in the assay; separation of free and bound radioactivity; counting and data processing; quality control and standardization. (orig.)

  2. Advanced Technology for Engineering Education

    Science.gov (United States)

    Noor, Ahmed K. (Compiler); Malone, John B. (Compiler)

    1998-01-01

    This document contains the proceedings of the Workshop on Advanced Technology for Engineering Education, held at the Peninsula Graduate Engineering Center, Hampton, Virginia, February 24-25, 1998. The workshop was jointly sponsored by the University of Virginia's Center for Advanced Computational Technology and NASA. Workshop attendees came from NASA, other government agencies, industry and universities. The objectives of the workshop were to assess the status of advanced technologies for engineering education and to explore the possibility of forming a consortium of interested individuals/universities for curriculum reform and development using advanced technologies. The presentations covered novel delivery systems and several implementations of new technologies for engineering education. Certain materials and products are identified in this publication in order to specify adequately the materials and products that were investigated in the research effort. In no case does such identification imply recommendation or endorsement of products by NASA, nor does it imply that the materials and products are the only ones or the best ones available for this purpose. In many cases equivalent materials and products are available and would probably produce equivalent results.

  3. Advanced batteries materials science aspects

    CERN Document Server

    Huggins, Robert A

    2008-01-01

    Storage and conversion are critical components of important energy-related technologies. This title employs materials science concepts and tools to describe the features that control the behavior of advanced electrochemical storage systems. It focuses on the basic phenomena that determine the properties of the components.

  4. REVIEW: Advances in Electronic Marketing

    OpenAIRE

    YILMAZ, Reviewed By Dr. Ayhan

    2005-01-01

    There are many challenges facing organizations today as they incorporate electronic marketing methods into their strategy. Advances in Electronic Marketing examines these challenges within three major themes: the global environment, the strategic/technological realm, and the buyer behavior of online consumers.

  5. Advances in time series forecasting

    CERN Document Server

    Cagdas, Hakan Aladag

    2012-01-01

    Readers will learn how these methods work and how these approaches can be used to forecast real life time series. The hybrid forecasting model is also explained. Data presented in this e-book is problem based and is taken from real life situations. It is a valuable resource for students, statisticians and working professionals interested in advanced time series analysis.

  6. Recent advances in silage microbiology

    Science.gov (United States)

    Recent advances in our understanding of silage microbiology are reviewed. The ability to extract microbial DNA from silages, amplify portions of DNA, and use the amplified regions to identify strains of microorganisms is at the core of the changes occurring recently in silage microbiology. These dev...

  7. OPTIMIZATION OF ADVANCED FILTER SYSTEMS

    Energy Technology Data Exchange (ETDEWEB)

    R.A. Newby; G.J. Bruck; M.A. Alvin; T.E. Lippert

    1998-04-30

    Reliable, maintainable and cost effective hot gas particulate filter technology is critical to the successful commercialization of advanced, coal-fired power generation technologies, such as IGCC and PFBC. In pilot plant testing, the operating reliability of hot gas particulate filters have been periodically compromised by process issues, such as process upsets and difficult ash cake behavior (ash bridging and sintering), and by design issues, such as cantilevered filter elements damaged by ash bridging, or excessively close packing of filtering surfaces resulting in unacceptable pressure drop or filtering surface plugging. This test experience has focused the issues and has helped to define advanced hot gas filter design concepts that offer higher reliability. Westinghouse has identified two advanced ceramic barrier filter concepts that are configured to minimize the possibility of ash bridge formation and to be robust against ash bridges should they occur. The ''inverted candle filter system'' uses arrays of thin-walled, ceramic candle-type filter elements with inside-surface filtering, and contains the filter elements in metal enclosures for complete separation from ash bridges. The ''sheet filter system'' uses ceramic, flat plate filter elements supported from vertical pipe-header arrays that provide geometry that avoids the buildup of ash bridges and allows free fall of the back-pulse released filter cake. The Optimization of Advanced Filter Systems program is being conducted to evaluate these two advanced designs and to ultimately demonstrate one of the concepts in pilot scale. In the Base Contract program, the subject of this report, Westinghouse has developed conceptual designs of the two advanced ceramic barrier filter systems to assess their performance, availability and cost potential, and to identify technical issues that may hinder the commercialization of the technologies. A plan for the Option I, bench

  8. Advanced scenarios for ITER operation

    International Nuclear Information System (INIS)

    In thermonuclear fusion research using magnetic confinement, the tokamak is the leading candidate for achieving conditions required for a reactor. An international experiment, ITER is proposed as the next essential and critical step on the path to demonstrating the scientific and technological feasibility of fusion energy. ITER is to produce and study plasmas dominated by self heating. This would give unique opportunities to explore, in reactor relevant conditions, the physics of α-particle heating, plasma turbulence and turbulent transport, stability limits to the plasma pressure and exhaust of power and particles. Important new results obtained in experiments, theory and modelling, enable an improved understanding of the physical processes occurring in tokamak plasmas and give enhanced confidence in ITER achieving its goals. In particular, progress has been made in research to raise the performance of tokamaks, aimed to extend the discharge pulse length towards steady-state operation (advanced scenarios). Standard tokamak discharges have a current density increasing monotonically towards the centre of the plasma. Advanced scenarios on the other hand use a modified current density profile. Different advanced scenarios range from (i) plasmas that sustain a central region with a flat current density profile (zero magnetic shear), capable of operating stationary at high plasma pressure, to (ii) discharges with an off axis maximum of the current density profile (reversed magnetic shear in the core), able to form internal transport barriers, to increase the confinement of the plasma. The physics of advanced tokamak discharges is described, together with an overview of recent results from different tokamak experiments. International collaboration between experiments aims to provide a better understanding, control and optimisation of these plasmas. The ability to explore advanced scenarios in ITER is very desirable, in order to verify the result obtained in experiments

  9. NATO Advanced Research Workshop on Molecular Engineering for Advanced Materials

    CERN Document Server

    Schaumburg, Kjeld

    1995-01-01

    An important aspect of molecular engineering is the `property directed' synthesis of large molecules and molecular assemblies. Synthetic expertise has advanced to a state which allows the assembly of supramolecules containing thousands of atoms using a `construction kit' of molecular building blocks. Expansion in the field is driven by the appearance of new building blocks and by an improved understanding of the rules for joining them in the design of nanometer-sized devices. Another aspect is the transition from supramolecules to materials. At present no single molecule (however large) has been demonstrated to function as a device, but this appears to be only a matter of time. In all of this research, which has a strongly multidisciplinary character, both existing and yet to be developed analytical techniques are and will remain indispensable. All this and more is discussed in Molecular Engineering for Advanced Materials, which provides a masterly and up to date summary of one of the most challenging researc...

  10. Advances in Nuclear Monitoring Technologies

    Science.gov (United States)

    Park, Brent

    2006-03-01

    Homeland security requires low-cost, large-area detectors for locating and identifying weapons-usable nuclear materials and monitors for radiological isotopes that are more robust than current systems. Recent advances in electronics materials and nanotechnology, specifically organic semiconductors and inorganic quantum dots, offer potential improvements. We provide an overview of the physical processes involved in radiation detection using these new materials in the design of new device structures. Examples include recent efforts on quantum dots, as well as more traditional radiation-detecting materials such as CdZnTe and high-pressure xenon. Detector improvements demand not only new materials but also enhanced data-analysis tools that reduce false alarms and thus increase the quality of decisions. Additional computing power on hand-held platforms should enable the application of advanced algorithms to radiation-detection problems in the field, reducing the need to transmit data and thus delay analysis.

  11. Advances in water resources technology

    Science.gov (United States)

    The presentation of technological advances in the field of water resources will be the focus of Advances in Water Resources Technology, a conference to be held in Athens, Greece, March 20-23, 1991. Organized by the European Committee for Water Resources Management, in cooperation with the National Technical University of Athens, the conference will feature state-of-the art papers, contributed original research papers, and poster papers. Session subjects will include surface water, groundwater, water resources conservation, water quality and reuse, computer modeling and simulation, real-time control of water resources systems, and institutions and methods for technology.The official language of the conference will be English. Special meetings and discussions will be held for investigating methods of effective technology transfer among European countries. For this purpose, a wide representation of research institutions, universities and companies involved in water resources technology will be attempted.

  12. Management of Advanced Laryngeal Cancer

    Directory of Open Access Journals (Sweden)

    Patrick Sheahan

    2014-04-01

    Full Text Available Squamous cell carcinoma of the larynx continues to be the commonest head and neck cancer in many Western countries. The larynx plays a key role for many essential functions, including breathing, voice production, airway protection, and swallowing. The goals of laryngeal cancer treatment are thus to provide best possible oncologic control, while optimizing functional outcomes. In recent decades, the treatment paradigm for advanced laryngeal cancer has shifted from one of primary surgery (total laryngectomy as gold standard, toward non-surgical organ-preserving treatment using radiotherapy or chemoradiotherapy. However, concerns have emerged regarding functional outcomes after chemoradiotherapy, as well as possible decreased overall survival in patients with laryngeal cancer. The purpose of the present review is to review surgical and non-surgical options for treatment of advanced laryngeal cancer, as well as the evidence supporting each of these.

  13. SP-100 advanced technology program

    International Nuclear Information System (INIS)

    The goal of the triagency SP-100 Program is to develop long-lived, compact, lightweight, survivable nuclear reactor space power systems for application to the power range 50 kWe to 1 MWe. The successful development of these systems should enable or significantly enhance many of the future NASA civil and commercial missions. The NASA SP-100 Advanced Technology Program strongly augments the parallel SP-100 Ground Engineering System Development program and enhances the chances for success of the overall SP-100 program. The purpose of this paper is to discuss the key technical elements of the Advanced Technology Program and the progress made in the initial year and a half of the project

  14. Soft computing in advanced robotics

    CERN Document Server

    Kobayashi, Ichiro; Kim, Euntai

    2014-01-01

    Intelligent system and robotics are inevitably bound up; intelligent robots makes embodiment of system integration by using the intelligent systems. We can figure out that intelligent systems are to cell units, while intelligent robots are to body components. The two technologies have been synchronized in progress. Making leverage of the robotics and intelligent systems, applications cover boundlessly the range from our daily life to space station; manufacturing, healthcare, environment, energy, education, personal assistance, logistics. This book aims at presenting the research results in relevance with intelligent robotics technology. We propose to researchers and practitioners some methods to advance the intelligent systems and apply them to advanced robotics technology. This book consists of 10 contributions that feature mobile robots, robot emotion, electric power steering, multi-agent, fuzzy visual navigation, adaptive network-based fuzzy inference system, swarm EKF localization and inspection robot. Th...

  15. Switzerland advances payments to CERN

    CERN Multimedia

    2002-01-01

    In the picture, Charles Kleiber (third from left) visits the TI8 tunnel with (left to right) Jean-Luc Baldy, Head of the LHC civil engineering group, Luciano Maiani, CERN Director-General, Jean-Pierre Ruder, Swiss Delegate to CERN Council, Guy Hentsch, Personal adviser to the Director-General, Michel Buchs and Frédéric Chavan, representatives of the firm Prader Losinger. The State Secretary for Science and Research in Switzerland, Charles Kleiber, signed an agreement with CERN last week for an advancement of contributions from his country. The Confédération Helvétique will make an advanced payment of 90 million CHF. There will be no interest involved in this payment and the amount of money will be deducted from Switzerland's ordinary contributions to CERN in later years.

  16. AGATA - Advanced Gamma Tracking Array

    CERN Document Server

    Akkoyun, S; Alikhani, B; Ameil, F; de Angelis, G; Arnold, L; Astier, A; Ataç, A; Aubert, Y; Aufranc, C; Austin, A; Aydin, S; Azaiez, F; Badoer, S; Balabanski, D L; Barrientos, D; Baulieu, G; Baumann, R; Bazzacco, D; Beck, F A; Beck, T; Bednarczyk, P; Bellato, M; Bentley, M A; Benzoni, G; Berthier, R; Berti, L; Beunard, R; Bianco, G Lo; Birkenbach, B; Bizzeti, P G; Bizzeti-Sona, A M; Blanc, F Le; Blasco, J M; Blasi, N; Bloor, D; Boiano, C; Borsato, M; Bortolato, D; Boston, A J; Boston, H C; Bourgault, P; Boutachkov, P; Bouty, A; Bracco, A; Brambilla, S; Brawn, I P; Brondi, A; Broussard, S; Bruyneel, B; Bucurescu, D; Burrows, I; Bürger, A; Cabaret, S; Cahan, B; Calore, E; Camera, F; Capsoni, A; Carrió, F; Casati, G; Castoldi, M; Cederwall, B; Cercus, J -L; Chambert, V; Chambit, M El; Chapman, R; Charles, L; Chavas, J; Clément, E; Cocconi, P; Coelli, S; Coleman-Smith, P J; Colombo, A; Colosimo, S; Commeaux, C; Conventi, D; Cooper, R J; Corsi, A; Cortesi, A; Costa, L; Crespi, F C L; Cresswell, J R; Cullen, D M; Curien, D; Czermak, A; Delbourg, D; Depalo, R; Descombes, T; Désesquelles, P; Detistov, P; Diarra, C; Didierjean, F; Dimmock, M R; Doan, Q T; Domingo-Pardo, C; Doncel, M; Dorangeville, F; Dosme, N; Drouen, Y; Duchêne, G; Dulny, B; Eberth, J; Edelbruck, P; Egea, J; Engert, T; Erduran, M N; Ertürk, S; Fanin, C; Fantinel, S; Farnea, E; Faul, T; Filliger, M; Filmer, F; Finck, Ch; de France, G; Gadea, A; Gast, W; Geraci, A; Gerl, J; Gernhäuser, R; Giannatiempo, A; Giaz, A; Gibelin, L; Givechev, A; Goel, N; González, V; Gottardo, A; Grave, X; Grȩbosz, J; Griffiths, R; Grint, A N; Gros, P; Guevara, L; Gulmini, M; Görgen, A; Ha, H T M; Habermann, T; Harkness, L J; Harroch, H; Hauschild, K; He, C; Hernández-Prieto, A; Hervieu, B; Hess, H; Hüyük, T; Ince, E; Isocrate, R; Jaworski, G; Johnson, A; Jolie, J; Jones, P; Jonson, B; Joshi, P; Judson, D S; Jungclaus, A; Kaci, M; Karkour, N; Karolak, M; Kaşkaş, A; Kebbiri, M; Kempley, R S; Khaplanov, A; Klupp, S; Kogimtzis, M; Kojouharov, I; Korichi, A; Korten, W; Kröll, Th; Krücken, R; Kurz, N; Ky, B Y; Labiche, M; Lafay, X; Lavergne, L; Lazarus, I H; Leboutelier, S; Lefebvre, F; Legay, E; Legeard, L; Lelli, F; Lenzi, S M; Leoni, S; Lermitage, A; Lersch, D; Leske, J; Letts, S C; Lhenoret, S; Lieder, R M; Linget, D; Ljungvall, J; Lopez-Martens, A; Lotodé, A; Lunardi, S; Maj, A; van der Marel, J; Mariette, Y; Marginean, N; Marginean, R; Maron, G; Mather, A R; Mȩczyński, W; Mendéz, V; Medina, P; Melon, B; Menegazzo, R; Mengoni, D; Merchan, E; Mihailescu, L; Michelagnoli, C; Mierzejewski, J; Milechina, L; Million, B; Mitev, K; Molini, P; Montanari, D; Moon, S; Morbiducci, F; Moro, R; Morrall, P S; Möller, O; Nannini, A; Napoli, D R; Nelson, L; Nespolo, M; Ngo, V L; Nicoletto, M; Nicolini, R; Noa, Y Le; Nolan, P J; Norman, M; Nyberg, J; Obertelli, A; Olariu, A; Orlandi, R; Oxley, D C; Özben, C; Ozille, M; Oziol, C; Pachoud, E; Palacz, M; Palin, J; Pancin, J; Parisel, C; Pariset, P; Pascovici, G; Peghin, R; Pellegri, L; Perego, A; Perrier, S; Petcu, M; Petkov, P; Petrache, C; Pierre, E; Pietralla, N; Pietri, S; Pignanelli, M; Piqueras, I; Podolyak, Z; Pouhalec, P Le; Pouthas, J; Pugnére, D; Pucknell, V F E; Pullia, A; Quintana, B; Raine, R; Rainovski, G; Ramina, L; Rampazzo, G; La Rana, G; Rebeschini, M; Recchia, F; Redon, N; Reese, M; Reiter, P; Regan, P H; Riboldi, S; Richer, M; Rigato, M; Rigby, S; Ripamonti, G; Robinson, A P; Robin, J; Roccaz, J; Ropert, J -A; Rossé, B; Alvarez, C Rossi; Rosso, D; Rubio, B; Rudolph, D; Saillant, F; Şahin, E; Salomon, F; Salsac, M -D; Salt, J; Salvato, G; Sampson, J; Sanchis, E; Santos, C; Schaffner, H; Schlarb, M; Scraggs, D P; Seddon, D; Şenyiğit, M; Sigward, M -H; Simpson, G; Simpson, J; Slee, M; Smith, J F; Sona, P; Sowicki, B; Spolaore, P; Stahl, C; Stanios, T; Stefanova, E; Stézowski, O; Strachan, J; Suliman, G; Söderström, P -A; Tain, J L; Tanguy, S; Tashenov, S; Theisen, Ch; Thornhill, J; Tomasi, F; Toniolo, N; Touzery, R; Travers, B; Triossi, A; Tripon, M; Tun-Lanoë, K M M; Turcato, M; Unsworth, C; Ur, C A; Valiente-Dobon, J J; Vandone, V; Vardaci, E; Venturelli, R; Veronese, F; Veyssiere, Ch; Viscione, E; Wadsworth, R; Walker, P M; Warr, N; Weber, C; Weisshaar, D; Wells, D; Wieland, O; Wiens, A; Wittwer, G; Wollersheim, H J; Zocca, F; Zamfir, N V; Ziȩbliński, M; Zucchiatti, A

    2011-01-01

    The Advanced GAmma Tracking Array (AGATA) is a European project to develop and operate the next generation gamma-ray spectrometer. AGATA is based on the technique of gamma-ray energy tracking in electrically segmented high-purity germanium crystals. This technique requires the accurate determination of the energy, time and position of every interaction as a gamma ray deposits its energy within the detector volume. Reconstruction of the full interaction path results in a detector with very high efficiency and excellent spectral response. The realization of gamma-ray tracking and AGATA is a result of many technical advances. These include the development of encapsulated highly-segmented germanium detectors assembled in a triple cluster detector cryostat, an electronics system with fast digital sampling and a data acquisition system to process the data at a high rate. The full characterization of the crystals was measured and compared with detector-response simulations. This enabled pulse-shape analysis algorith...

  17. Quantum mechanics II advanced topics

    CERN Document Server

    Rajasekar, S

    2015-01-01

    Quantum Mechanics II: Advanced Topics uses more than a decade of research and the authors’ own teaching experience to expound on some of the more advanced topics and current research in quantum mechanics. A follow-up to the authors introductory book Quantum Mechanics I: The Fundamentals, this book begins with a chapter on quantum field theory, and goes on to present basic principles, key features, and applications. It outlines recent quantum technologies and phenomena, and introduces growing topics of interest in quantum mechanics. The authors describe promising applications that include ghost imaging, detection of weak amplitude objects, entangled two-photon microscopy, detection of small displacements, lithography, metrology, and teleportation of optical images. They also present worked-out examples and provide numerous problems at the end of each chapter.

  18. Advanced Vehicle Testing and Evaluation

    Energy Technology Data Exchange (ETDEWEB)

    Garetson, Thomas [The Clarity Group, Incorporated, Chicago, IL (United States)

    2013-03-31

    The objective of the United States (U.S.) Department of Energy's (DOEs) Advanced Vehicle Testing and Evaluation (AVTE) project was to provide test and evaluation services for advanced technology vehicles, to establish a performance baseline, to determine vehicle reliability, and to evaluate vehicle operating costs in fleet operations.Vehicles tested include light and medium-duty vehicles in conventional, hybrid, and all-electric configurations using conventional and alternative fuels, including hydrogen in internal combustion engines. Vehicles were tested on closed tracks and chassis dynamometers, as well as operated on public roads, in fleet operations, and over prescribed routes. All testing was controlled by procedures developed specifically to support such testing.

  19. Advancing Autonomous Structural Health Monitoring

    OpenAIRE

    Grisso, Benjamin Luke

    2007-01-01

    The focus of this dissertation is aimed at advancing autonomous structural health monitoring. All the research is based on developing the impedance method for monitoring structural health. The impedance technique utilizes piezoelectric patches to interrogate structures of interested with high frequency excitations. These patches are bonded directly to the structure, so information about the health of the structure can be seen in the electrical impedance of the piezoelectric patch. However, tr...

  20. Advancing the technologies of CANDU

    International Nuclear Information System (INIS)

    CANDU standard product design will continue to evolve, building upon the success of current operating units. Progressive improvements and enhancements will continue to be made to the CANDU system with heavy water moderated, pressure tube reactor technology of high neutron efficiency, based on the results of advanced technology R and D and operational experience from operating CANDU stations. The directions of development will respond to customer's requirements for economical, reliable and safe generating stations

  1. Global sourcing of advanced services

    OpenAIRE

    Ørberg Jensen, Peter D.; Petersen, Bent

    2011-01-01

    In this exploratory study we take a strategic management approach to global sourcing of advanced services. We discuss in which ways conventional sourcing differs from strategic sourcing and what impels firms to aim for the latter (or, prevent them from doing so). Potentially, strategic global sourcing of services has high returns, but is also associated with high risks and needs for organizational changes. Strategic global sourcing may therefore be outside firms’ “comfort zone”...

  2. Advances in magnetic resonance 2

    CERN Document Server

    Waugh, John S

    2013-01-01

    Advances in Magnetic Resonance, Volume 2, features a mixture of experimental and theoretical contributions. The book contains four chapters and begins with an ambitious and general treatment of the problem of signal-to-noise ratio in magnetic resonance. This is followed by separate chapters on the interpretation of nuclear relaxation in fluids, with special reference to hydrogen; and various aspects of molecular theory of importance in NMR.

  3. Computational photography: advances and challenges

    OpenAIRE

    Lam, EYM

    2011-01-01

    In the mid-1990s when digital photography began to enter the consumer market, Professor Joseph Goodman and I set out to explore how computation would impact the imaging system design. The field of study has since grown to be known as computational photography. In this paper I'll describe some of its recent advances and challenges, and discuss what the future holds. © 2011 Copyright Society of Photo-Optical Instrumentation Engineers (SPIE).

  4. Advances in magnetic resonance 10

    CERN Document Server

    Waugh, John S

    2013-01-01

    Advances in Magnetic Resonance, Volume 10, presents a variety of contributions to the theory and practice of magnetic resonance. The book contains three chapters that examine superoperators in magnetic resonance; ultrasonically modulated paramagnetic resonance; and the utility of electron paramagnetic resonance (EPR) and electron-nuclear double-resonance (ENDOR) techniques for studying low-frequency modes of atomic fluctuations and their significance for understanding the mechanism of structural phase transitions in solids.

  5. Imprecise reliabilities: experiences and advances

    International Nuclear Information System (INIS)

    Imprecise probability theories are considered useful in reliability and risk assessments, but some of them were found to be unsatisfactory. This paper summarizes the authors' experience in dealing with the Dempster-Shafer theory of evidence and demonstrates the authors' advances in the application of the theory of coherent imprecise probabilities for reliability assessments. The obtained lower and upper reliabilities of series, parallel and general systems have very specific useful properties that cannot be obtained in the framework of standard probability theory

  6. Recent Advances in Petroleum Microbiology

    OpenAIRE

    Van Hamme, Jonathan D.; Singh, Ajay; Ward, Owen P.

    2003-01-01

    Recent advances in molecular biology have extended our understanding of the metabolic processes related to microbial transformation of petroleum hydrocarbons. The physiological responses of microorganisms to the presence of hydrocarbons, including cell surface alterations and adaptive mechanisms for uptake and efflux of these substrates, have been characterized. New molecular techniques have enhanced our ability to investigate the dynamics of microbial communities in petroleum-impacted ecosys...

  7. Advanced Model of Electromagnetic Launcher

    Directory of Open Access Journals (Sweden)

    Karel Leubner

    2015-01-01

    Full Text Available An advanced 2D model of electromagnetic launcher is presented respecting the influence of eddy currents induced in the accelerated ferromagnetic body. The time evolution of electromagnetic field in the system, corresponding forces acting on the projectile and time evolutions of its velocity and current in the field circuit are solved numerically using own application Agros2d. The results are then processed and evaluated in Wolfram Mathematica. The methodology is illustrated with an example whose results are discussed.

  8. Advanced computations in plasma physics

    International Nuclear Information System (INIS)

    Scientific simulation in tandem with theory and experiment is an essential tool for understanding complex plasma behavior. In this paper we review recent progress and future directions for advanced simulations in magnetically confined plasmas with illustrative examples chosen from magnetic confinement research areas such as microturbulence, magnetohydrodynamics, magnetic reconnection, and others. Significant recent progress has been made in both particle and fluid simulations of fine-scale turbulence and large-scale dynamics, giving increasingly good agreement between experimental observations and computational modeling. This was made possible by innovative advances in analytic and computational methods for developing reduced descriptions of physics phenomena spanning widely disparate temporal and spatial scales together with access to powerful new computational resources. In particular, the fusion energy science community has made excellent progress in developing advanced codes for which computer run-time and problem size scale well with the number of processors on massively parallel machines (MPP's). A good example is the effective usage of the full power of multi-teraflop (multi-trillion floating point computations per second) MPP's to produce three-dimensional, general geometry, nonlinear particle simulations which have accelerated progress in understanding the nature of turbulence self-regulation by zonal flows. It should be emphasized that these calculations, which typically utilized billions of particles for thousands of time-steps, would not have been possible without access to powerful present generation MPP computers and the associated diagnostic and visualization capabilities. In general, results from advanced simulations provide great encouragement for being able to include increasingly realistic dynamics to enable deeper physics insights into plasmas in both natural and laboratory environments. The associated scientific excitement should serve to

  9. Therapeutic advances in muscular dystrophy

    OpenAIRE

    Leung, Doris G.; Wagner, Kathryn R.

    2013-01-01

    The muscular dystrophies comprise a heterogeneous group of genetic disorders that produce progressive skeletal muscle weakness and wasting. There has been rapid growth and change in our understanding of these disorders in recent years, and advances in basic science are being translated into increasing numbers of clinical trials. This review will discuss therapeutic developments in 3 of the most common forms of muscular dystrophy: Duchenne muscular dystrophy, facioscapulohumeral muscular dystr...

  10. Recent advances in Chinese palaeontology

    OpenAIRE

    Xu, Xing; Luo, Zhe-Xi; Rong, Jia-Yu

    2009-01-01

    Discoveries are a driving force for progress in palaeontology. Palaeontology as a discipline of scientific inquiry has gained many fresh insights into the history of life, from the discoveries of many new fossils in China in the last 20 years, and from the new ideas derived from these fossils. This special issue of Proceedings of Royal Society B entitled Recent Advances in Chinese Palaeontology selects some of the very latest studies aimed at resolving the current problems of palaeontology an...

  11. Advances in information storage systems

    CERN Document Server

    Bhushan, Bharat

    1995-01-01

    The series Advances in Information Storage Systems covers a wide range of interdisciplinary technical areas, related to magnetic or optical storage systems. The following nonexhaustive list is indicative of the scope of the topics: Friction, Adhesion, Wear and Lubrications, Coatings, Solid Mechanics, Air Flow, Contamination, Instrumentation, Dynamics, Shock and Vibration, Controls, Head and Suspension Design, Actuators, Spindle and Actuator Motors and Bearings, Structure of Thin Films, Corrosion, Long-Term Reliability, Materials and Processing, Manufacturing and Automation, Economics.This volu

  12. Animal cloning: advances and prospects

    OpenAIRE

    Chuaire Lilian; Sánchez Magda Carolina; Franco María Liliana

    2004-01-01

    Few recent advances have revolutionized the developmental biology as the animal cloning has. Since the birth of Dolly, the sheep, in 1996, which was the first derived clone of a mature animal, a new scientific era began. It has been characterized by growing demystification that differentiated cells are unalterable entities in its nuclear organization and chromatin structure, and by a better understanding of the mechanisms that regulate the development. Throughout this paper, we will review ...

  13. Recent advances in pulse oximetry

    OpenAIRE

    Cannesson, Maxime; Talke, Pekka

    2009-01-01

    Conventional pulse oximetry uses two wavelengths of light (red and infrared) transmitted through a finger and a photodetector to analyze arterial hemoglobin oxygen saturation and pulse rate. Recent advances in pulse oximetry include: extended analysis of the photo plethysmographic waveform; use of multiple wavelengths of light to quantify methemoglobin, carboxyhemoglobin and total hemoglobin content in blood; and use of electronic processes to improve pulse oximeter signal processing during c...

  14. Selected advances in materials research

    International Nuclear Information System (INIS)

    Several findings emanating from materials research that should have a beneficial impact on technological advancement in the future are described. The report deals with the GRAPHNOL, a new class of high-temperature brazing alloy for joining refractory components, gel-sphere-pac process for manufacture of nuclear fuel, and noble-metal fuel cladding for service in radioisotope thermoelectric generators designed to provide auxiliary power aboard spacecraft for planetary exploration

  15. Recent Advances in Complex Networks

    Institute of Scientific and Technical Information of China (English)

    2002-01-01

    Dramatic advances in the field of complex networks have been witnessed in the past few years. This paper reviews some important results in this direction of rapidly evolving research, with emphasis on the relationship between the dynamics and the topology of complex networks. Basic quantities and typical examples of various complex networks are described. Robustness of connectivity and epidemic dynamics in complex networks are evaluated.

  16. Advances in Management of Retinoblastoma

    Institute of Scientific and Technical Information of China (English)

    Kensei; Minoda

    1992-01-01

    Retinobiastoma is a highly malignant intraocular tumor of children that requires accurate diagnosis to prompt treatment. This article reviewed clinical, pathological and follow-up data on 1 147 cases of retinobiastoma registered in Japan from 1975 to 1982. It is obvious that the prognosis of children with retinobiastoma has improved remarkably in recent years. The current advances in the management of the retinobiastoma were discussed.

  17. Large floating structures technological advances

    CERN Document Server

    Wang, BT

    2015-01-01

    This book surveys key projects that have seen the construction of large floating structures or have attained detailed conceptual designs. This compilation of key floating structures in a single volume captures the innovative features that mark the technological advances made in this field of engineering, and will provide a useful reference for ideas, analysis, design, and construction of these unique and emerging urban projects to offshore and marine engineers, urban planners, architects and students.

  18. Advanced Thermally Stable Jet Fuels

    Energy Technology Data Exchange (ETDEWEB)

    A. Boehman; C. Song; H. H. Schobert; M. M. Coleman; P. G. Hatcher; S. Eser

    1998-01-01

    The Penn State program in advanced thermally stable jet fuels has five components: 1) development of mechanisms of degradation and solids formation; 2) quantitative measurement of growth of sub-micrometer and micrometer-sized particles during thermal stressing; 3) characterization of carbonaceous deposits by various instrumental and microscopic methods; 4) elucidation of the role of additives in retarding the formation of carbonaceous solids; and 5) assessment of the potential of producing high yields of cycloalkanes and hydroaromatics from coal.

  19. Advances in percutaneous stone surgery

    Directory of Open Access Journals (Sweden)

    Christopher Hartman

    2015-01-01

    Full Text Available Treatment of large renal stones has changed considerably in recent years. The increasing prevalence of nephrolithiasis has mandated that urologists perform more surgeries for large renal calculi than before, and this has been met with improvements in percutaneous stone surgery. In this review paper, we examine recent developments in percutaneous stone surgery, including advances in diagnosis and preoperative planning, renal access, patient position, tract dilation, nephroscopes, lithotripsy, exit strategies, and post-operative antibiotic prophylaxis.

  20. Advanced Fuel Bundles for PHWRS

    International Nuclear Information System (INIS)

    The fuel used by NPCIL presently is natural uranium dioxide in the form of 19- element fuel bundles for 220 MWe PHWRs and 37-element fuel bundles for the TAPP-3&4 540 MWe units. The new 700 MWe PHWRs also use 37-element fuel bundles. These bundles are of short 0.5 m length of circular geometry. The cladding is of collapsible type made of Zircaloy-4 material. PHWRs containing a string of short length fuel bundles and the on-power refueling permit flexibility in using different advanced fuel designs and in core fuel management schemes. Using this flexibility, alternative fuel concepts are tried in Indian PHWRs. The advances in PHWR fuel designs are governed by the desire to use resources other than uranium, improve fuel economics by increasing fuel burnup and reduce overall spent nuclear fuel waste and improve reactor safety. The rising uranium prices are leading to a relook into the Thorium based fuel designs and reprocessed Uranium based and Plutonium based MOX designs and are expected to play a major role in future. The requirement of synergism between different type of reactors also plays a role. Increase in fuel burnup beyond 15 000 MW∙d/TeU in PHWRs, using higher fissile content materials like slightly enriched uranium, Mixed Oxide and Thorium Oxide in place of natural uranium in fuel elements, was studied many PHWR operating countries. The work includes reactor physics studies and test irradiation in research reactors and power reactors. Due to higher fissile content these bundles will be capable of delivering higher burnup than the natural uranium bundles. In India the fuel cycle flexibility of PHWRs is demonstrated by converting this type of technical flexibility to the real economy by irradiating these different types of advanced fuel materials namely Thorium, MOX, SEU, etc. The paper gives a review of the different advanced fuel design concepts studied for Indian PHWRs. (author)

  1. Advanced Performance Hydraulic Wind Energy

    Science.gov (United States)

    Jones, Jack A.; Bruce, Allan; Lam, Adrienne S.

    2013-01-01

    The Jet Propulsion Laboratory, California Institute of Technology, has developed a novel advanced hydraulic wind energy design, which has up to 23% performance improvement over conventional wind turbine and conventional hydraulic wind energy systems with 5 m/sec winds. It also has significant cost advantages with levelized costs equal to coal (after carbon tax rebate). The design is equally applicable to tidal energy systems and has passed preliminary laboratory proof-of-performance tests, as funded by the Department of Energy.

  2. GT Advanced Technologies Inc. Bankruptcy

    OpenAIRE

    Souply-Pierard, Fernand

    2014-01-01

    GT Advanced Technologies (GTAT), une société américaine de haute technologie produisant du saphir synthétique (fournisseur d’Apple), a fait faillite ce lundi 6 octobre 2014 et s’est placée sous la protection du chapitre 11 de la loi américaine sur la faillite. Cette faillite était-elle prévisible ?

  3. PHARMACOTHERAPY IN ADVANCED THYROID CANCER

    OpenAIRE

    Voichiţa Mogoş

    2008-01-01

    Thyroid cancers are the most common carcinomas of the endocrine system. Their behavior depends of histology, extension of the disease and patients-related factors. Differentiated thyroid cancers arising from follicular epithelium may be cured with combined surgery and radioiodine therapy. In 10-15 % of cases patients may develop metastases which are cause of death. In advanced differentiated thyroid cancers of follicular origin combined therapy with radioiodine and TSH suppression may result ...

  4. Recent advances of protein microarrays

    OpenAIRE

    Hultschig, Claus; Kreutzberger, Jürgen; Seitz, Harald; Konthur, Zoltán; Büssow, Konrad; Lehrach, Hans

    2006-01-01

    Technological innovations and novel applications have greatly advanced the field of protein microarrays. Over the past two years, different types of protein microarrays have been used for serum profiling, protein abundance determinations, and identification of proteins that bind DNA or small compounds. However, considerable development is still required to ensure common quality standards and to establish large content repertoires. Here, we summarize applications available to date and discuss ...

  5. Advanced tufted carpet patterning technology

    Institute of Scientific and Technical Information of China (English)

    2006-01-01

    After a review of the tufting industry's development, and a brief introduction to available systems for producing patterned tufted carpets, the principle of ICN (Individually Controlled Needle) and the related advanced tufting technology Colortec are presented. Finally, Colortec machine, Axminster weaving machine, and Wilton loom are compared. It is believed that the Cobble Colortec machine is a significant jump forward in the tufted carpets industry as it now allows access to all major carpet markets in a competitive fashion.

  6. Advances in Procedural Techniques - Antegrade

    OpenAIRE

    Wilson, William; Spratt, James C.

    2014-01-01

    There have been many technological advances in antegrade CTO PCI, but perhaps most importantly has been the evolution of the “hybrid’ approach where ideally there exists a seamless interplay of antegrade wiring, antegrade dissection re-entry and retrograde approaches as dictated by procedural factors. Antegrade wire escalation with intimal tracking remains the preferred initial strategy in short CTOs without proximal cap ambiguity. More complex CTOs, however, usually require either a retrogra...

  7. Advances in magnetic resonance 4

    CERN Document Server

    Waugh, John S

    2013-01-01

    Advances in Magnetic Resonance, Volume 4 deals with the relaxation, irradiation, and other dynamical effects that is specific to systems having resolved structure in their magnetic resonance spectra. This book discusses the anisotropic rotation of molecules in liquids by NMR quadrupolar relaxation; rotational diffusion constants; alternating linewidth effect; and theoretical formulations of the problem. The line shapes in high-resolution NMR; matrix representations of the equations of motion; matrix representations of the equations of motion; and intramolecular hydrogen bonds are also delibera

  8. Theory Advances in BSM Physics

    CERN Document Server

    McCullough, Matthew

    2016-01-01

    Rather than attempting to summarise the full spectrum of recent advances in Beyond the Standard Model (BSM) theory, which are many, in this talk I will instead take the opportunity to focus on two frameworks related to the hierarchy problem currently receiving significant attention. They are the `Twin Higgs' and the `Relaxion'. I will summarise the basic underlying structure of these theories at a non-expert level and highlight some interesting phenomenological signatures or outstanding problems.

  9. Advanced energy conversion and application

    International Nuclear Information System (INIS)

    This VDI-report 1029 contains the manuscripts of 45 lectures which have been held on the expert meeting ''Advanced energy conversion and application''. The following 3 main subjects have been dealt with: I electric power stations and heating and power stations, II industrial energy technology, III energy supply of buildings. For each of the 45 manuscripts, a separated assessment with regard to the content has been elaborated. (HW)

  10. Advances in magnetic resonance 11

    CERN Document Server

    Waugh, John S

    2013-01-01

    Advances in Magnetic Resonance, Volume 11, presents a variety of contributions to the theory and practice of magnetic resonance. The book contains three chapters and begins with a discussion of the principles and applications of dynamic nuclear polarization, with emphasis on molecular motions and collisions, intermolecular couplings, and chemical interactions. Subsequent chapters focus on the assessment of a proposed broadband decoupling method and studies of time-domain (or Fourier transform) multiple-quantum nuclear magnetic resonance.

  11. New Advances in Cytometric Instrumentation

    OpenAIRE

    Lopez, Peter

    2013-01-01

    The growing field of flow cytometry industry continues to produce exciting and innovative developments. Although the CyTOF mass spectrometry flow cytometer is one of the most revolutionary new developments (to be presented in another session), other advances have built upon the original FACS technology. The trends in cytometric instrumentation include smaller, easier to use analyzers and cell sorters, instrumentation capable of detecting multiple fluorescent colors even if their spectra overl...

  12. Recent advances on tea polyphenols

    OpenAIRE

    Kanwar, Jyoti; Taskeen, Mujtaba; Mohammad, Imthiyaz; HUO, CONGDE; CHAN, TAK HANG; Dou, Qing Ping

    2012-01-01

    Over the past decade many scientific and medical studies have focused on green tea for its long-purported health benefits. There is convincing evidence that tea is a cup of life. It has multiple preventive and therapeutic effects. This review thus focuses on the recent advances of tea polyphenols and their applications in the prevention and treatment of human cancers. Of the various polyphenols in tea, (−)-Epigallocatechin-3-gallate (EGCG) is the most abundant, and active compound studied in ...

  13. Challenges and Advances in Nanotoxicology

    OpenAIRE

    Tanguay, Robert L.

    2014-01-01

    This Special Issue of Nanomaterials examines the potential for engineered nanomaterials to negatively impact biological systems and highlights some advances in evaluating key areas of their hazard potential. Nanomaterial science is evolving rapidly with the generation of more complex nanostructures with exciting potential applications. Keeping modern toxicology abreast of this innovation to the point that it guides a safer nanotechnology presents an equally exciting and eminently worthwhile c...

  14. Challenges and Advances in Nanotoxicology

    Directory of Open Access Journals (Sweden)

    Robert L. Tanguay

    2014-08-01

    Full Text Available This Special Issue of Nanomaterials examines the potential for engineered nanomaterials to negatively impact biological systems and highlights some advances in evaluating key areas of their hazard potential. Nanomaterial science is evolving rapidly with the generation of more complex nanostructures with exciting potential applications. Keeping modern toxicology abreast of this innovation to the point that it guides a safer nanotechnology presents an equally exciting and eminently worthwhile challenge. [...

  15. Advanced Architectures for Astrophysical Supercomputing

    OpenAIRE

    Barsdell, Benjamin R.; Barnes, David G.; Fluke, Christopher J.

    2010-01-01

    Astronomers have come to rely on the increasing performance of computers to reduce, analyze, simulate and visualize their data. In this environment, faster computation can mean more science outcomes or the opening up of new parameter spaces for investigation. If we are to avoid major issues when implementing codes on advanced architectures, it is important that we have a solid understanding of our algorithms. A recent addition to the high-performance computing scene that highlights this point...

  16. Preface: Advances in solar physics

    Science.gov (United States)

    Georgoulis, Manolis K.; Nakariakov, Valery M.

    2015-12-01

    The idea for this special issue of Advances in Space Research (ASR) was formulated during the 14th European Solar Physics Meeting (ESPM-14) that took place in Dublin, Ireland in September 2014. Since ASR does not publish conference proceedings, it was decided to extend a general call to the international solar-physics community for manuscripts pertinent to the following thematic areas: New and upcoming heliospheric observational and data assimilation facilities.

  17. Fiscal Limits in Advanced Economies

    OpenAIRE

    Eric M. Leeper; Walker, Todd B

    2011-01-01

    Aging populations in advanced economies are placing ever-increasing demands on government spending in the form of old-age benefits. Economies that have promised substantially more benefits than they have made provision to finance are heading into a prolonged era of fiscal stress. Unresolved fiscal stress raises the possibility that the economies will hit their fiscal limits where taxes and spending no longer adjust to stabilize debt. In such economies, monetary policy may lose its ability to ...

  18. Advance Care Planning i sykehjem

    OpenAIRE

    Hydal, Anne-Marthe Bering

    2015-01-01

    Bakgrunn: Advance care planning (ACP) er en kommunikativ prosess, som utforsker pasienters preferanser for fremtidig medisinsk behandling og pleie ved livets slutt. Flere land har tatt i bruk ACP, men i Norge finnes få føringer for nedtegnelse av pasientpreferanser. Hensikt: Undersøke hvilke ACP programmer som er implementert i sykehjem utenfor Norge, og hva de ulike programmene inneholder. Videre å undersøke hvilke implementeringsstrategier som er tatt i bruk, og hvilke erfaringer som beskri...

  19. Review of advanced imaging techniques

    Directory of Open Access Journals (Sweden)

    Yu Chen

    2012-01-01

    Full Text Available Pathology informatics encompasses digital imaging and related applications. Several specialized microscopy techniques have emerged which permit the acquisition of digital images ("optical biopsies" at high resolution. Coupled with fiber-optic and micro-optic components, some of these imaging techniques (e.g., optical coherence tomography are now integrated with a wide range of imaging devices such as endoscopes, laparoscopes, catheters, and needles that enable imaging inside the body. These advanced imaging modalities have exciting diagnostic potential and introduce new opportunities in pathology. Therefore, it is important that pathology informaticists understand these advanced imaging techniques and the impact they have on pathology. This paper reviews several recently developed microscopic techniques, including diffraction-limited methods (e.g., confocal microscopy, 2-photon microscopy, 4Pi microscopy, and spatially modulated illumination microscopy and subdiffraction techniques (e.g., photoactivated localization microscopy, stochastic optical reconstruction microscopy, and stimulated emission depletion microscopy. This article serves as a primer for pathology informaticists, highlighting the fundamentals and applications of advanced optical imaging techniques.

  20. ADVANCED FUELS CAMPAIGN 2013 ACCOMPLISHMENTS

    Energy Technology Data Exchange (ETDEWEB)

    Not Listed

    2013-10-01

    The mission of the Advanced Fuels Campaign (AFC) is to perform Research, Development, and Demonstration (RD&D) activities for advanced fuel forms (including cladding) to enhance the performance and safety of the nation’s current and future reactors; enhance proliferation resistance of nuclear fuel; effectively utilize nuclear energy resources; and address the longer-term waste management challenges. This includes development of a state-of-the art Research and Development (R&D) infrastructure to support the use of “goal-oriented science-based approach.” In support of the Fuel Cycle Research and Development (FCRD) program, AFC is responsible for developing advanced fuels technologies to support the various fuel cycle options defined in the Department of Energy (DOE) Nuclear Energy Research and Development Roadmap, Report to Congress, April 2010. Accomplishments made during fiscal year (FY) 2013 are highlighted in this report, which focuses on completed work and results. The process details leading up to the results are not included; however, the technical contact is provided for each section.

  1. GE's advanced nuclear reactor designs

    International Nuclear Information System (INIS)

    The excess of US electrical generating capacity which has existed for the past 15 years is coming to an end as we enter the 1990s. Environmental and energy security issues associated with fossil fuels are kindling renewed interest in the nuclear option. The importance of these issues are underscored by the National Energy Strategy (NES) which calls for actions which open-quotes are designed to ensure that the nuclear power option is available to utilities.close quotes Utilities, utility associations, and nuclear suppliers, under the leadership of the Nuclear Power Oversight Committee (NPOC), have jointly developed a 14-point strategic plan aimed at establishing a predictable regulatory environment, standardized and pre-licensed Advanced Light Water Reactor (ALWR) nuclear plants, resolving the long-term waste management issue, and other open-quotes enabling conditions.close quotes GE is participating in this national effort and GE's family of advanced nuclear power plants feature two reactor designs, developed on a common technology base, aimed at providing a new generation of nuclear plants to provide safe, clean, economical electricity to the world's utilities in the 1990s and beyond. Together, the large-size (1300 MWe) Advanced Boiling Water Reactor (ABWR) and the small-size (600 MWe) Simplified Boiling Water Reactor (SBWR) are innovative, near-term candidates for expanding electrical generating capacity in the US and worldwide. Both possess the features necessary to do so safety, reliably, and economically

  2. Advanced materials for energy storage.

    Science.gov (United States)

    Liu, Chang; Li, Feng; Ma, Lai-Peng; Cheng, Hui-Ming

    2010-02-23

    Popularization of portable electronics and electric vehicles worldwide stimulates the development of energy storage devices, such as batteries and supercapacitors, toward higher power density and energy density, which significantly depends upon the advancement of new materials used in these devices. Moreover, energy storage materials play a key role in efficient, clean, and versatile use of energy, and are crucial for the exploitation of renewable energy. Therefore, energy storage materials cover a wide range of materials and have been receiving intensive attention from research and development to industrialization. In this Review, firstly a general introduction is given to several typical energy storage systems, including thermal, mechanical, electromagnetic, hydrogen, and electrochemical energy storage. Then the current status of high-performance hydrogen storage materials for on-board applications and electrochemical energy storage materials for lithium-ion batteries and supercapacitors is introduced in detail. The strategies for developing these advanced energy storage materials, including nanostructuring, nano-/microcombination, hybridization, pore-structure control, configuration design, surface modification, and composition optimization, are discussed. Finally, the future trends and prospects in the development of advanced energy storage materials are highlighted. PMID:20217798

  3. Advancing Concentrating Solar Power Research (Fact Sheet)

    Energy Technology Data Exchange (ETDEWEB)

    2014-02-01

    Researchers at the National Renewable Energy Laboratory (NREL) provide scientific, engineering, and analytical expertise to help advance innovation in concentrating solar power (CSP). This fact sheet summarizes how NREL is advancing CSP research.

  4. Intermediate/Advanced Research Design and Statistics

    Science.gov (United States)

    Ploutz-Snyder, Robert

    2009-01-01

    The purpose of this module is To provide Institutional Researchers (IRs) with an understanding of the principles of advanced research design and the intermediate/advanced statistical procedures consistent with such designs

  5. III Advanced Ceramics and Applications Conference

    CERN Document Server

    Gadow, Rainer; Mitic, Vojislav; Obradovic, Nina

    2016-01-01

    This is the Proceedings of III Advanced Ceramics and Applications conference, held in Belgrade, Serbia in 2014. It contains 25 papers on various subjects regarding preparation, characterization and application of advanced ceramic materials.

  6. Notes: Several Problems with Advance Ruling (Japanese)

    OpenAIRE

    KOHYAMA Hiroyuki

    2010-01-01

    In Japan, most tax scholars and practitioners have believed that the introduction of "advance-ruling" would dispel the uncertainty about tax consequences and facilitate transactions. However, Givati (2009) shows that in the U.S. advance rulings (Private Letter Ruling and Advance Pricing Agreements) are not frequently used. Givati (2009) argues that some taxpayers avoid applying for advance ruling not because of the "direct cost" of the application, but because of strategic disadvantages. For ...

  7. ICONE-4: Proceedings. Volume 2: Advanced reactors

    International Nuclear Information System (INIS)

    The proceedings for this conference are contained in 5 volumes. This volume is divided into the following areas: advanced reactor requirements; advanced reactor design and analysis; arrangement and construction; specific reactor designs; demonstration testing; safety systems and analysis; component demonstration testing; advanced reactor containment design; licensing topics and updates; accelerator applications and spallation sources; and advanced reactor development. Separate abstracts were prepared for most papers in this volume

  8. Containment flooding: Operating and advanced BWRs

    International Nuclear Information System (INIS)

    Currently, the emergency procedures, or even the strategies for operating advanced BWRs, have not been drafted and factored into the design of the advanced plants. This paper examines one particular strategy, containment flooding, that may be implemented in advanced BWRs. This paper then provides some of the lessons learned from currently operating plants regarding the effectiveness of this strategy

  9. Flipped Classrooms for Advanced Science Courses

    Science.gov (United States)

    Tomory, Annette; Watson, Sunnie Lee

    2015-01-01

    This article explains how issues regarding dual credit and Advanced Placement high school science courses could be mitigated via a flipped classroom instructional model. The need for advanced high school courses will be examined initially, followed by an analysis of advanced science courses and the reform they are experiencing. Finally, it will…

  10. Advanced Placement: More than a Test.

    Science.gov (United States)

    Colwell, Richard

    1990-01-01

    Encourages music teachers to work with students interested in advanced placement (AP) music courses. Discusses the logistics and advantages of placing students in these courses. Describes the Advanced Placement Listening and Literature and the Advanced Placement Theory courses and examinations. Outlines the examination scoring method and looks at…

  11. 40 CFR 35.2101 - Advanced treatment.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 1 2010-07-01 2010-07-01 false Advanced treatment. 35.2101 Section 35... STATE AND LOCAL ASSISTANCE Grants for Construction of Treatment Works § 35.2101 Advanced treatment. Projects proposing advanced treatment shall be awarded grant assistance only after the project has...

  12. Advanced nuclear systems. Review study

    International Nuclear Information System (INIS)

    The task of this review study is to from provide an overview of the developments in the field of the various advanced nuclear systems, and to create the basis for more comprehensive studies of technology assessment. In an overview the concepts for advanced nuclear systems pursued worldwide are subdivided into eight subgroups. A coarse examination raster (set pattern) is developed to enable a detailed examination of the selected systems. In addition to a focus on enhanced safety features, further aspects are also taken into consideration, like the lowering of the proliferation risk, the enhancement of the economic competitiveness of the facilities and new usage possibilities (for instance concerning the relaxation of the waste disposal problem or the usage of alternative fuels to uranium). The question about the expected time span for realization and the discussion about the obstacles on the way to a commercially usable reactor also play a substantial role as well as disposal requirements as far as they can be presently recognized. In the central chapter of this study, the documentation of the representatively selected concepts is evaluated as well as existing technology assessment studies and expert opinions. In a few cases where this appears to be necessary, according technical literature, further policy advisory reports, expert statements as well as other relevant sources are taken into account. Contradictions, different assessments and dissents in the literature as well as a few unsettled questions are thus indicated. The potential of advanced nuclear systems with respect to economical and societal as well as environmental objectives cannot exclusively be measured by the corresponding intrinsic or in comparison remarkable technical improvements. The acceptability of novel or improved systems in nuclear technology will have to be judged by their convincing solutions for the crucial questions of safety, nuclear waste and risk of proliferation of nuclear weapons

  13. Center for Advanced Separation Technology

    Energy Technology Data Exchange (ETDEWEB)

    Honaker, Rick

    2013-09-30

    The U.S. is the largest producer of mining products in the world. In 2011, U.S. mining operations contributed a total of $232 billion to the nation’s GDP plus $138 billion in labor income. Of this the coal mining industry contributed a total of $97.5 billion to GDP plus $53 billion in labor income. Despite these contributions, the industry has not been well supported with research and development funds as compared to mining industries in other countries. To overcome this problem, the Center for Advanced Separation Technologies (CAST) was established to develop technologies that can be used by the U.S. mining industry to create new products, reduce production costs, and meet environmental regulations. Originally set up by Virginia Tech and West Virginia University, CAST is now a five-university consortium – Virginia Tech, West Virginia University, University of Kentucky, University of Utah and Montana Tech, - that is supported through U.S. DOE Cooperative Agreement No. DE-FE0000699, Center for Advanced Separation Technology. Much of the research to be conducted with Cooperative Agreement funds will be longer term, high-risk, basic research and will be carried out in two broad areas: Advanced Pre-Combustion Clean Coal Technologies and Gas-Gas Separations. Distribution of funds is handled via competitive solicitation of research proposals through Site Coordinators at the five member universities. These were reviewed and the selected proposals were forwarded these to the DOE/NETL Project Officer for final review and approval. The successful projects are listed below by category, along with abstracts from their final reports.

  14. Advanced wastewater treatment system (SEADS)

    International Nuclear Information System (INIS)

    'Full text:' This presentation will describe the nature, scope, and findings of a third-party evaluation of a wastewater treatment technology identified as the Advanced Wastewater Treatment System Inc.'s Superior Extended Aerobic Digester System (SEADS). SEADS is an advanced miniaturized wastewater treatment plant that can meet advanced wastewater treatment standards for effluent public reuse. SEADS goes beyond primary and secondary treatment operations to reduce nutrients such as nitrogen and phosphorus, which are typically found in excessive quantities in traditional wastewater treatment effluent. The objective of this evaluation will be to verify the performance and reliability of the SEADS to treat wastewater from a variety of sources, including domestic wastewater and commercial industrial wastewater. SEADS utilizes remote telemetry equipment to achieve added reliability and reduces monitoring costs as compared to many package wastewater treatment plants. The evaluation process will be overseen and coordinated by the Environmental Technology Evaluation Center (EvTEC), a program of the Civil Engineering Research Foundation (CERF), the research and technology transfer arm of the American Society of Civil Engineers (ASCE). EvTEC is a pilot program evaluating innovative environmental technologies under the US Environmental Protection Agency's (USEPA) Environmental Technology Verification (ETV) Program. Among other performance issues, the SEADS technology evaluation will address its ability to treat low flows-from remote individual and clustered housing applications, and individual commercial applications in lieu of a main station conventional wastewater treatment plant. The unneeded reliance on particular soil types for percolation and the improved effluent water quality over septic systems alone look to make these types of package treatment plants a viable option for rural communities, small farms, and other low-flow remote settings. Added benefits to be examined

  15. A course in advanced calculus

    CERN Document Server

    Borden, Robert S

    1997-01-01

    This remarkable undergraduate-level text offers a study in calculus that simultaneously unifies the concepts of integration in Euclidean space while at the same time giving students an overview of other areas intimately related to mathematical analysis. The author achieves this ambitious undertaking by shifting easily from one related subject to another. Thus, discussions of topology, linear algebra, and inequalities yield to examinations of innerproduct spaces, Fourier series, and the secret of Pythagoras. Beginning with a look at sets and structures, the text advances to such topics as lim

  16. Advanced Communications Technology Satellite (ACTS)

    Science.gov (United States)

    Gedney, Richard T.; Schertler, Ronald J.

    1989-06-01

    The NASA Advanced Communications Technology Satellite (ACTS) was conceived to help maintain U.S. leadership in the world's communications-satellite market. This experimental satellite is expected to be launched by NASA in 1992 and to furnish the technology necessary for establishing very small aperture terminal digital networks which provide on-demand full-mesh connectivity, and 1.544-MBPS services with only a single hop. Utilizing on-board switching and processing, each individual voice or data circuit can be separately routed to any location in the network. This paper provides an overview of the ACTS and discusses the value of the technology for future communications systems.

  17. Advances in astronomy and astrophysics

    CERN Document Server

    Kopal, Zdenek

    1963-01-01

    Advances in Astronomy and Astrophysics, Volume 2 brings together numerous research works on different aspects of astronomy and astrophysics. This volume is composed of six chapters and begins with a summary of observational record on twilight extensions of the Venus cusps. The next chapter deals with the common and related properties of binary stars, with emphasis on the evaluation of their cataclysmic variables. Cataclysmic variables refer to an object in one of three classes: dwarf nova, nova, or supernova. These topics are followed by discussions on the eclipse phenomena and the eclipses i

  18. Advanced Neutron Source operating philosophy

    International Nuclear Information System (INIS)

    An operating philosophy and operations cost estimate were prepared to support the Conceptual Design Report for the Advanced Neutron Source (ANS), a new research reactor planned for the Oak Ridge National Laboratory (ORNL). The operating philosophy was part of the initial effort of the ANS Human Factors Program, was integrated into the conceptual design, and addressed operational issues such as remote vs local operation; control room layout and responsibility issues; role of the operator; simulation and training; staffing levels; and plant computer systems. This paper will report on the overall plans and purpose for the operations work, the results of the work done for conceptual design, and plans for future effort

  19. Advances in bacterial specific imaging

    Energy Technology Data Exchange (ETDEWEB)

    Wareham, David; Das, Satya [St Bartholomew' s Hospital, London (United Kingdom). Dept. of Medical Microbiology; London Univ. (United Kingdom). Queen Mary' s School of Medicine and Dentistry. Inst. of Cell and Molecular Science

    2005-10-15

    Nuclear medicine is a powerful diagnostic technique able to detect inflammatory foci in human disease. A wide range of agents have been evaluated for their ability to distinguish lesions due to microbial infection from those due to sterile inflammation. Advances continue to be made on the use of radiolabelled antibiotics which as well as being highly specific in the diagnosis of infection may be useful in monitoring the treatment and course of disease. Here we provide an update on in-vitro and clinical studies with a number of established and novel radiopharmaceuticals. (author)

  20. Advanced Material Rendering in Blender

    Czech Academy of Sciences Publication Activity Database

    Hatka, Martin; Haindl, Michal

    2012-01-01

    Roč. 11, č. 2 (2012), s. 15-23. ISSN 1081-1451 R&D Projects: GA ČR GAP103/11/0335; GA ČR GA102/08/0593 Grant ostatní: CESNET(CZ) 387/2010; CESNET(CZ) 409/2011 Institutional support: RVO:67985556 Keywords : realistic material rendering * bidirectional texture function * Blender Subject RIV: BD - Theory of Information http://library.utia.cas.cz/separaty/2013/RO/haindl-advanced material rendering in blender.pdf

  1. Advanced light source master oscillator

    International Nuclear Information System (INIS)

    The Master Oscillator of the Advanced Light Source operates at a frequency of 499.654 MHz which is the 328th harmonic of the storage ring. The oscillator is capable of providing up to a maximum of ± 500 KHz frequency deviation for various experimental purposes. Provisions for external signal injection as well as using an external signal source have been designed into the unit. A power distribution system has also been included to provide signals for various parts of the ALS machine and user requirements. The Master Oscillator is made up with modules housed in a Euro chassis. 4 refs., 7 figs

  2. Advanced SOA tools and applications

    CERN Document Server

    Brzezinski, Jerzy; Cellary, Wojciech; Grzech, Adam; Zielinski, Krzysztof

    2014-01-01

    This book presents advanced software development tools for construction, deployment and governance of Service Oriented Architecture (SOA) applications. Novel technical concepts and paradigms, formulated during the research stage and during development of such tools are presented and illustrated by practical usage examples. Hence this book will be of interest not only to theoreticians but also to engineers who cope with real-life problems. Additionally, each chapter contains an overview of related work, enabling comparison of the proposed concepts with exiting solutions in various areas of the SOA development process. This makes the book interesting also for students and scientists who investigate similar issues.

  3. Nanocarbons for advanced energy storage

    CERN Document Server

    Feng, Xinliang

    2015-01-01

    This first volume in the series on nanocarbons for advanced applications presents the latest achievements in the design, synthesis, characterization, and applications of these materials for electrochemical energy storage. The highly renowned series and volume editor, Xinliang Feng, has put together an internationally acclaimed expert team who covers nanocarbons such as carbon nanotubes, fullerenes, graphenes, and porous carbons. The first two parts focus on nanocarbon-based anode and cathode materials for lithium ion batteries, while the third part deals with carbon material-based supercapacit

  4. Recent advances in methane activation

    Energy Technology Data Exchange (ETDEWEB)

    Huuska, M.; Kataja, K. [VTT Chemical Technology, Espoo (Finland)

    1996-12-31

    Considerable work has been done in the research and development of methane conversion technologies. Although some promising conversion processes have been demonstrated, further advances in engineering and also in the chemistry are needed before these technologies become commercial. High-temperature processes, e.g. the oxidative coupling of methane, studied thoroughly during the last 15 years, suffer from severe theoretical yield limits and poor economics. In the long term, the most promising approaches seem to be the organometallic and, especially, the biomimetic activation of methane. (author) (22 refs.)

  5. Advanced express web application development

    CERN Document Server

    Keig, Andrew

    2013-01-01

    A practical book, guiding the reader through the development of a single page application using a feature-driven approach.If you are an experienced JavaScript developer who wants to build highly scalable, real-world applications using Express, this book is ideal for you. This book is an advanced title and assumes that the reader has some experience with node, Javascript MVC web development frameworks, and has heard of Express before, or is familiar with it. You should also have a basic understanding of Redis and MongoDB. This book is not a tutorial on Node, but aims to explore some of the more

  6. A bridge to advanced mathematics

    CERN Document Server

    Sentilles, Dennis

    2011-01-01

    This helpful workbook-style ""bridge"" book introduces students to the foundations of advanced mathematics, spanning the gap between a practically oriented calculus sequence and subsequent courses in algebra and analysis with a more theoretical slant. Part 1 focuses on logic and number systems, providing the most basic tools, examples, and motivation for the manner, method, and concerns of higher mathematics. Part 2 covers sets, relations, functions, infinite sets, and mathematical proofs and reasoning. Author Dennis Sentilles also discusses the history and development of mathematics as well a

  7. Advances in bacterial specific imaging

    International Nuclear Information System (INIS)

    Nuclear medicine is a powerful diagnostic technique able to detect inflammatory foci in human disease. A wide range of agents have been evaluated for their ability to distinguish lesions due to microbial infection from those due to sterile inflammation. Advances continue to be made on the use of radiolabelled antibiotics which as well as being highly specific in the diagnosis of infection may be useful in monitoring the treatment and course of disease. Here we provide an update on in-vitro and clinical studies with a number of established and novel radiopharmaceuticals. (author)

  8. Advanced concepts in quantum mechanics

    CERN Document Server

    Esposito, Giampiero; Miele, Gennaro; Sudarshan, George

    2015-01-01

    Introducing a geometric view of fundamental physics, starting from quantum mechanics and its experimental foundations, this book is ideal for advanced undergraduate and graduate students in quantum mechanics and mathematical physics. Focusing on structural issues and geometric ideas, this book guides readers from the concepts of classical mechanics to those of quantum mechanics. The book features an original presentation of classical mechanics, with the choice of topics motivated by the subsequent development of quantum mechanics, especially wave equations, Poisson brackets and harmonic oscillators. It also presents new treatments of waves and particles and the symmetries in quantum mechanics, as well as extensive coverage of the experimental foundations.

  9. Advanced materials for clean energy

    CERN Document Server

    Xu (Kyo Jo), Qiang

    2015-01-01

    Arylamine-Based Photosensitizing Metal Complexes for Dye-Sensitized Solar CellsCheuk-Lam Ho and Wai-Yeung Wongp-Type Small Electron-Donating Molecules for Organic Heterojunction Solar CellsZhijun Ning and He TianInorganic Materials for Solar Cell ApplicationsYasutake ToyoshimaDevelopment of Thermoelectric Technology from Materials to GeneratorsRyoji Funahashi, Chunlei Wan, Feng Dang, Hiroaki Anno, Ryosuke O. Suzuki, Takeyuki Fujisaka, and Kunihito KoumotoPiezoelectric Materials for Energy HarvestingDeepam Maurya, Yongke Yan, and Shashank PriyaAdvanced Electrode Materials for Electrochemical Ca

  10. Advances in magnetic resonance 5

    CERN Document Server

    Waugh, John S

    2013-01-01

    Advances in Magnetic Resonance, Volume 5 deals with the interpretation of ESR spectra and provides descriptions of experimental apparatus. This book discusses the halogen hyperfine interactions; organic radicals in single crystals; pulsed-Fourier-transform nuclear magnetic resonance spectrometer; and inhomogenizer and decoupler. The spectrometers for multiple-pulse NMR; weak collision theory of relaxation in the rotating frame; and spin Hamiltonian for the electron spin resonance of irradiated organic single crystals are also deliberated. This text likewise covers the NMR in helium three and m

  11. Advances in magnetic resonance 12

    CERN Document Server

    Waugh, John S

    2013-01-01

    Advances in Magnetic Resonance, Volume 12, presents a variety of contributions to the theory and practice of magnetic resonance. The book contains six chapters and begins with a discussion of diffusion and self-diffusion measurements by nuclear magnetic resonance. This is followed by separate chapters on spin-lattice relaxation time in hydrogen isotope mixtures; the principles of optical detection of nuclear spin alignment and nuclear quadropole resonance; and the spin-1 behavior, including the relaxation of the quasi-invariants of the motion of a system of pairs of dipolar coupled spin-1/2 nu

  12. Advanced Artificial Intelligence Technology Testbed

    Science.gov (United States)

    Anken, Craig S.

    1993-01-01

    The Advanced Artificial Intelligence Technology Testbed (AAITT) is a laboratory testbed for the design, analysis, integration, evaluation, and exercising of large-scale, complex, software systems, composed of both knowledge-based and conventional components. The AAITT assists its users in the following ways: configuring various problem-solving application suites; observing and measuring the behavior of these applications and the interactions between their constituent modules; gathering and analyzing statistics about the occurrence of key events; and flexibly and quickly altering the interaction of modules within the applications for further study.

  13. Advanced calculus of several variables

    CERN Document Server

    Kumar, Devendra

    2014-01-01

    ADVANCED CALCULUS OF SEVERAL VARIABLES covers important topics of Transformations and topology on Euclidean in n-space Rn Functions of several variables, Differentiation in Rn, Multiple integrals and Integration in Rn. The topics have been presented in a simple clear and coherent style with a number of examples and exercises. Proofs have been made direct and simple. Unsolved problems just after relevant articles in the form of exercises and typical problems followed by suggestions have been given. This book will help the reader work on the problems of Numerical Analysis, Operations Research, Differential Equations and Engineering applications.

  14. Alarm system advances and innovations

    International Nuclear Information System (INIS)

    Alarm: 'a signal (as a loud noise or flashing light) that warns or alerts; also: a device that signals... '. This statement, this definition as simple as it is sums up every alarm system for every control system that has ever existed, but what it's missing from it is the complexity and uniqueness required by a Nuclear Power Plant. With advances in computerized control and engineering technologies within these plants, the need for more comprehensive alarm control and monitoring systems is as critical as the operation itself. (authors)

  15. Advanced fusion concepts: project summaries

    International Nuclear Information System (INIS)

    This report contains descriptions of the activities of all the projects supported by the Advanced Fusion Concepts Branch of the Office of Fusion Energy, US Department of Energy. These descriptions are project summaries of each of the individual projects, and contain the following: title, principle investigators, funding levels, purpose, approach, progress, plans, milestones, graduate students, graduates, other professional staff, and recent publications. Information is given for each of the following programs: (1) reverse-field pinch, (2) compact toroid, (3) alternate fuel/multipoles, (4) stellarator/torsatron, (5) linear magnetic fusion, (6) liners, and (7) Tormac

  16. Advanced C and C++ compiling

    CERN Document Server

    Stevanovic, Milan

    2014-01-01

    Learning how to write C/C++ code is only the first step. To be a serious programmer, you need to understand the structure and purpose of the binary files produced by the compiler: object files, static libraries, shared libraries, and, of course, executables.Advanced C and C++ Compiling explains the build process in detail and shows how to integrate code from other developers in the form of deployed libraries as well as how to resolve issues and potential mismatches between your own and external code trees.With the proliferation of open source, understanding these issues is increasingly the res

  17. Advanced Fission Reactor Program objectives

    International Nuclear Information System (INIS)

    The objective of an advanced fission reactor program should be to develop an economically attractive, safe, proliferation-resistant fission reactor. To achieve this objective, an aggressive and broad-based research and development program is needed. Preliminary work at Brookhaven National Laboratory shows that a reasonable goal for a research program would be a reactor combining as many as possible of the following features: (1) initial loading of uranium enriched to less than 15% uranium 235, (2) no handling of fuel for the full 30-year nominal core life, (3) inherent safety ensured by core physics, and (4) utilization of natural uranium at least 5 times as efficiently as light water reactors

  18. Advances in astronomy and astrophysics

    CERN Document Server

    Kopal, Zdenek

    1968-01-01

    Advances in Astronomy and Astrophysics, Volume 6 brings together numerous research works on different aspects of astronomy and astrophysics. This volume is composed of five chapters, and starts with the description of improved methods for analyzing and classifying families of periodic orbits in a conservative dynamical system with two degrees of freedom. The next chapter describes the variation of fractional luminosity of distorted components of close binary systems in the course of their revolution, or the accompanying changes in radial velocity. This topic is followed by discussions on vari

  19. Advances of Contraception in China

    Institute of Scientific and Technical Information of China (English)

    肖碧莲

    1994-01-01

    Family planning is an important component of reproductive health. Reduction in total fertility rate is closely related to the decrease of maternal and infant mortality rate and the advances in maternal and child health care. In the last two decades the reduction of total fertility rate from 5.6% in the 70s to 2. 5% in average at present occurs along with the decrease in maternal and infant mortality. This achievement should be attributed partly to the success in the development of contraceptive

  20. Advances in lung cancer surgery

    Directory of Open Access Journals (Sweden)

    Mark W Hennon

    2012-01-01

    Full Text Available The last few years have witnessed an explosion of the use of minimally invasive techniques for the detection, diagnosis, and treatment of all stages of lung cancer. The use of these techniques has improved the risk-benefit ratio of surgery and has made it more acceptable to patients considering lung surgery. They have also facilitated the delivery of multi-modality therapy to patients with advanced lung cancer. This review article summarizes current surgical techniques that represent the "cutting edge" of thoracic surgery for lung cancer.

  1. Advances in electron transfer chemistry

    CERN Document Server

    Mariano, Patrick S

    1993-01-01

    Advances in Electron Transfer Chemistry, Volume 3 presents studies that discuss findings in the various aspects of electron chemistry. The book is comprised of four chapters; each chapter reviews a work that tackles an issue in electron transfer chemistry. Chapter 1 discusses the photoinduced electron transfer in flexible biaryl donor-acceptor molecules. Chapter 2 tackles light-induced electron transfer in inorganic systems in homogeneous and heterogeneous phases. The book also covers internal geometry relaxation effects on electron transfer rates of amino-centered systems. The sequential elec

  2. Advances in magnetic resonance 6

    CERN Document Server

    Waugh, John S

    2013-01-01

    Advances in Magnetic Resonance, Volume 6 focuses on the theoretical and practical aspects of applying magnetic resonance methods to various problems in physical chemistry, emphasizing the different aspects of the exegesis of these problems. This book discusses the gas phase magnetic resonance of electronically excited molecules; techniques for observing excited electronic states; NMR studies in liquids at high pressure; and effect of pressure on self-diffusion in liquids. The nuclear magnetic resonance investigations of organic free radicals; measurement of proton coupling constants by NMR; an

  3. Advances in electron transfer chemistry

    CERN Document Server

    Mariano, Patrick S

    1995-01-01

    Advances in Electron Transfer Chemistry, Volume 4 presents the reaction mechanisms involving the movement of single electrons. This book discusses the electron transfer reactions in organic, biochemical, organometallic, and excited state systems. Organized into four chapters, this volume begins with an overview of the photochemical behavior of two classes of sulfonium salt derivatives. This text then examines the parameters that control the efficiencies for radical ion pair formation. Other chapters consider the progress in the development of parameters that control the dynamics and reaction p

  4. Advanced Spectroscopy Technique for Biomedicine

    Science.gov (United States)

    Zhao, Jianhua; Zeng, Haishan

    This chapter presents an overview of the applications of optical spectroscopy in biomedicine. We focus on the optical design aspects of advanced biomedical spectroscopy systems, Raman spectroscopy system in particular. Detailed components and system integration are provided. As examples, two real-time in vivo Raman spectroscopy systems, one for skin cancer detection and the other for endoscopic lung cancer detection, and an in vivo confocal Raman spectroscopy system for skin assessment are presented. The applications of Raman spectroscopy in cancer diagnosis of the skin, lung, colon, oral cavity, gastrointestinal tract, breast, and cervix are summarized.

  5. Advances in photovoltaics pt.3

    CERN Document Server

    Willeke, Gerhard P

    2014-01-01

    This volume is the third of a set of seven on the topic of photovoltaics. Solar cell-related technologies covered here include: ribbon silicon; heterojunction crystalline silicon; wafer equivalent crystalline silicon; and other advanced silicon solar cell structures and processes. Semiconductors and Semimetals has distinguished itself through the careful selection of well-known authors, editors, and contributors. Originally widely known as the ""Willardson and Beer"" Series, it has succeeded in publishing numerous landmark volumes and chapters. The series publishes timely, highly relevant v

  6. GPU Pro advanced rendering techniques

    CERN Document Server

    Engel, Wolfgang

    2010-01-01

    This book covers essential tools and techniques for programming the graphics processing unit. Brought to you by Wolfgang Engel and the same team of editors who made the ShaderX series a success, this volume covers advanced rendering techniques, engine design, GPGPU techniques, related mathematical techniques, and game postmortems. A special emphasis is placed on handheld programming to account for the increased importance of graphics on mobile devices, especially the iPhone and iPod touch.Example programs and source code can be downloaded from the book's CRC Press web page. 

  7. Latest Advances in Robot Kinematics

    CERN Document Server

    Husty, Manfred

    2012-01-01

    This book is  of interest to researchers inquiring about modern topics and methods in the kinematics, control and design of robotic manipulators. It considers the full range of robotic systems, including serial, parallel and cable driven manipulators, both planar and spatial. The systems range from being less than fully mobile to kinematically redundant to overconstrained. In addition to recognized areas, this book also presents recent advances in emerging areas such as the design and control of humanoids and humanoid subsystems, and the analysis, modeling and simulation of human body motions, as well as the mobility analysis of protein molecules and the development of machines which incorporate man.

  8. Advances in embedded computer vision

    CERN Document Server

    Kisacanin, Branislav

    2014-01-01

    This illuminating collection offers a fresh look at the very latest advances in the field of embedded computer vision. Emerging areas covered by this comprehensive text/reference include the embedded realization of 3D vision technologies for a variety of applications, such as stereo cameras on mobile devices. Recent trends towards the development of small unmanned aerial vehicles (UAVs) with embedded image and video processing algorithms are also examined. The authoritative insights range from historical perspectives to future developments, reviewing embedded implementation, tools, technolog

  9. Advanced Control of Electrochromic Windows

    OpenAIRE

    Scartezzini, Jean-Louis; Zarkadis, Nikos; Morel, Nicolas

    2013-01-01

    In our research we use the technology of electrochromic (EC) glazing to maximize the use of daylight and minimize the energy consumption in buildings while preserving visual and thermal comfort of the users. We propose an advanced automatic control of EC windows coupled with an anidolic daylighting system (ADS), blinds and dimmable fluorescent lights. EC windows with a visible transmittance range (Tv) of 0.15 – 0.50 were installed on the southern façade of an office room of the LESO experimen...

  10. Advanced light water reactor plant

    International Nuclear Information System (INIS)

    For nuclear power to be competitive with the other methods of electrical power generation the economic performance should be significantly improved by increasing the time spent on line generating electricity relative to time spent off-line conducting maintenance and refueling. Maintenance includes planned actions (surveillances) and unplanned actions (corrective maintenance) to respond to component degradation or failure. A methodology is described which is used to resolve maintenance related operating cycle length barriers. Advanced light water nuclear power plant is designed with the purpose to maximize online generating time by increasing operating cycle length. (author)

  11. Elementary algorithms from advanced mechanics

    CERN Document Server

    Chin, Siu A

    2016-01-01

    Most elementary numerical schemes found useful for solving classical trajectory problems are {\\it canonical transformations}. This fact should be make more widely known among teachers of computational physics and Hamiltonian mechanics. It is very surprising that in order to solve a simple second-order differential equation, one has to invoke the deepest part, the Poissonian formulation, of classical mechanics. From the perspective of advanced mechanics, there are no bewildering number of seemingly arbitrary elementary schemes based on Taylor's expansion. There are only {\\it two} canonical second-order algorithms, on the basis of which one can build numerical schemes of any order.

  12. Channel guiding for advanced accelerators

    Energy Technology Data Exchange (ETDEWEB)

    Milchberg, H.M. [Institute for Physical Science and Technology (United States); Durfee, C.G. III [Institute for Physical Science and Technology (United States); Antonsen, T.M. [Institute for Plasma Research, University of Maryland, College Park, Maryland, (United States) 20742; Mora, P. [Centre de Physique Theorique, Ecole Polytechnique, 91128 Palaiseau (France)

    1996-02-01

    The recent demonstration of optical guiding of high intensity laser pulses in plasma waveguides [C. G. Durfee III and H. M. Milchberg, Phys. Rev. Lett 71, 2409 (1993)] has opened the way to new advances in the development of compact laser-driven electron particle accelerators. We review plasma waveguide properties relevant to intense pulse guiding and electron acceleration and show that the shock driven channels described here are well suited for stabilization of a large class of laser-plasma instabilities deleterious to high intensity guiding over long distances. {copyright} {ital 1996 American Institute of Physics.}

  13. Advances in quantum electronics 3

    CERN Document Server

    Goodwin, D W

    2013-01-01

    Advances in Quantum Electronics, Volume 3 covers articles on the theoretical and experimental work undertaken in the field of optical pumping and on gaseous ion lasers. The book presents an overview of the optical-pumping field and a review of the use and properties of the density matrix as applied to the statistical behavior of assemblages of atoms or ions. The text discusses the application of the density matrix approach to the theory of optical-pumping r.f. spectroscopy and spin-exchange optical pumping. Optical-pumping experiments are also considered. The book further provides a comprehens

  14. Advances in magnetic resonance 3

    CERN Document Server

    Waugh, John S

    2013-01-01

    Advances in Magnetic Resonance, Volume 3, describes a number of important developments which are finding increasing application by chemists. The book contains five chapters and begins with a discussion of how the properties of random molecular rotations reflect themselves in NMR and how they show up, often differently, in other kinds of experiments. This is followed by separate chapters on the Kubo method, showing its equivalence to the Redfield approach in the cases of most general interest; the current state of dynamic nuclear polarization measurements in solutions and what they tell us abou

  15. Advances in magnetic resonance 1

    CERN Document Server

    Waugh, John S

    2013-01-01

    Advances in Magnetic Resonance, Volume 1, discusses developments in various areas of magnetic resonance. The subject matter ranges from original theoretical contributions through syntheses of points of view toward series of phenomena to critical and painstaking tabulations of experimental data. The book contains six chapters and begins with a discussion of the theory of relaxation processes. This is followed by separate chapters on the development of magnetic resonance techniques for studying rate processes in chemistry and the application of these techniques to various problems; the geometri

  16. Advanced diffusion processes and phenomena

    CERN Document Server

    Öchsner, Andreas; Belova, Irina

    2014-01-01

    This topical volume on Advanced Diffusion Processes and Phenomena addresses diffusion in a wider sense of not only mass diffusion but also heat diffusion in fluids and solids. Both diffusion phenomena play an important role in the characterization of engineering materials and corresponding structures. Understanding these different transport phenomena at many levels, from atomistic to macro, has therefore long attracted the attention of many researchers in materials science and engineering and related disciplines. The present topical volume captures a representative cross-section of some of the

  17. Recent advances on thermoelectric materials

    Institute of Scientific and Technical Information of China (English)

    Jin-cheng ZHENG

    2008-01-01

    By converting waste heat into electricity through the thermoelectric power of solids without producing greenhouse gas emissions,thermoelectric generators could be an important part of the solution to today's energy challenge.There has been a resurgence in the search for new materials for advanced thermoelectric energy conversion applications. In this paper,we will review recent efforts on improving thermoelectric efficiency. Particularly,several novel proof-of-principle approaches such as phonon disorder in phonon-glasselectron crystals,low dimensionality in nanostructured materials and charge-spin-orbital degeneracy in strongly correlated systems on thermoelectric performance will be discussed.

  18. Advanced fusion concepts: project summaries

    Energy Technology Data Exchange (ETDEWEB)

    None

    1980-12-01

    This report contains descriptions of the activities of all the projects supported by the Advanced Fusion Concepts Branch of the Office of Fusion Energy, US Department of Energy. These descriptions are project summaries of each of the individual projects, and contain the following: title, principle investigators, funding levels, purpose, approach, progress, plans, milestones, graduate students, graduates, other professional staff, and recent publications. Information is given for each of the following programs: (1) reverse-field pinch, (2) compact toroid, (3) alternate fuel/multipoles, (4) stellarator/torsatron, (5) linear magnetic fusion, (6) liners, and (7) Tormac. (MOW)

  19. Advances in magnetic resonance 9

    CERN Document Server

    Waugh, John S

    2013-01-01

    Advances in Magnetic Resonance, Volume 9 describes the magnetic resonance in split constants and dipolar relaxation. This book discusses the temperature-dependent splitting constants in the ESR spectra of organic free radicals; temperature-dependent splittings in ion pairs; and magnetic resonance induced by electrons. The electron impact excitation of atoms and molecules; intramolecular dipolar relaxation in multi-spin systems; and dipolar cross-correlation problem are also elaborated. This text likewise covers the NMR studies of molecules oriented in thermotropic liquid crystals and diffusion

  20. Advanced Transport Operating Systems Program

    Science.gov (United States)

    White, John J.

    1990-01-01

    NASA-Langley's Advanced Transport Operating Systems Program employs a heavily instrumented, B 737-100 as its Transport Systems Research Vehicle (TRSV). The TRSV has been used during the demonstration trials of the Time Reference Scanning Beam Microwave Landing System (TRSB MLS), the '4D flight-management' concept, ATC data links, and airborne windshear sensors. The credibility obtainable from successful flight test experiments is often a critical factor in the granting of substantial commitments for commercial implementation by the FAA and industry. In the case of the TRSB MLS, flight test demonstrations were decisive to its selection as the standard landing system by the ICAO.