WorldWideScience

Sample records for advanced generation inter-cross

  1. A Multiparent Advanced Generation Inter-Cross to fine-map quantitative traits in Arabidopsis thaliana.

    Directory of Open Access Journals (Sweden)

    Paula X Kover

    2009-07-01

    Full Text Available Identifying natural allelic variation that underlies quantitative trait variation remains a fundamental problem in genetics. Most studies have employed either simple synthetic populations with restricted allelic variation or performed association mapping on a sample of naturally occurring haplotypes. Both of these approaches have some limitations, therefore alternative resources for the genetic dissection of complex traits continue to be sought. Here we describe one such alternative, the Multiparent Advanced Generation Inter-Cross (MAGIC. This approach is expected to improve the precision with which QTL can be mapped, improving the outlook for QTL cloning. Here, we present the first panel of MAGIC lines developed: a set of 527 recombinant inbred lines (RILs descended from a heterogeneous stock of 19 intermated accessions of the plant Arabidopsis thaliana. These lines and the 19 founders were genotyped with 1,260 single nucleotide polymorphisms and phenotyped for development-related traits. Analytical methods were developed to fine-map quantitative trait loci (QTL in the MAGIC lines by reconstructing the genome of each line as a mosaic of the founders. We show by simulation that QTL explaining 10% of the phenotypic variance will be detected in most situations with an average mapping error of about 300 kb, and that if the number of lines were doubled the mapping error would be under 200 kb. We also show how the power to detect a QTL and the mapping accuracy vary, depending on QTL location. We demonstrate the utility of this new mapping population by mapping several known QTL with high precision and by finding novel QTL for germination data and bolting time. Our results provide strong support for similar ongoing efforts to produce MAGIC lines in other organisms.

  2. Development of next-generation mapping populations: Multi-parent Advanced Generation Inter-Cross (MAGIC) and Marker-Assisted Recurrent Selection (MARS) populations in peanut

    Science.gov (United States)

    Generation Inter-Cross (MAGIC) and Marker-Assisted Recurrent Selection (MARS) have been proposed and used in many crops to dissect complex traits or QTL. MAGIC allows for dissecting genomic structure, and for improving breeding populations by integrating multiple alleles from different parents. MAR...

  3. A multi-parent advanced generation inter-cross (MAGIC) population for genetic analysis and improvement of cowpea (Vigna unguiculata L. Walp.).

    Science.gov (United States)

    Huynh, Bao-Lam; Ehlers, Jeffrey D; Huang, Bevan Emma; Muñoz-Amatriaín, María; Lonardi, Stefano; Santos, Jansen R P; Ndeve, Arsenio; Batieno, Benoit J; Boukar, Ousmane; Cisse, Ndiaga; Drabo, Issa; Fatokun, Christian; Kusi, Francis; Agyare, Richard Y; Guo, Yi-Ning; Herniter, Ira; Lo, Sassoum; Wanamaker, Steve I; Xu, Shizhong; Close, Timothy J; Roberts, Philip A

    2018-03-01

    Multi-parent advanced generation inter-cross (MAGIC) populations are an emerging type of resource for dissecting the genetic structure of traits and improving breeding populations. We developed a MAGIC population for cowpea (Vigna unguiculata L. Walp.) from eight founder parents. These founders were genetically diverse and carried many abiotic and biotic stress resistance, seed quality and agronomic traits relevant to cowpea improvement in the United States and sub-Saharan Africa, where cowpea is vitally important in the human diet and local economies. The eight parents were inter-crossed using structured matings to ensure that the population would have balanced representation from each parent, followed by single-seed descent, resulting in 305 F 8 recombinant inbred lines each carrying a mosaic of genome blocks contributed by all founders. This was confirmed by single nucleotide polymorphism genotyping with the Illumina Cowpea Consortium Array. These lines were on average 99.74% homozygous but also diverse in agronomic traits across environments. Quantitative trait loci (QTLs) were identified for several parental traits. Loci with major effects on photoperiod sensitivity and seed size were also verified by biparental genetic mapping. The recombination events were concentrated in telomeric regions. Due to its broad genetic base, this cowpea MAGIC population promises breakthroughs in genetic gain, QTL and gene discovery, enhancement of breeding populations and, for some lines, direct releases as new varieties. © 2018 The Authors. The Plant Journal published by John Wiley & Sons Ltd and Society for Experimental Biology.

  4. Advanced technologies on steam generators

    Energy Technology Data Exchange (ETDEWEB)

    Sakata, Kaoru; Nakamura, Yuuki [Mitsubishi Heavy Industry Co., Takasago (Japan); Nakamori, Nobuo; Mizutani, Toshiyuki; Uwagawa, Seiichi; Saito, Itaru [Mitsubishi Heavy Industry Co., Kobe (Japan); Matsuoka, Tsuyoshi [Mitsubishi Heavy Industry Co., Yokohama (Japan)

    1997-12-31

    The thermal-hydraulic tests for a horizontal steam generator of a next-generation PWR (New PWR-21) were performed. The purpose of these tests is to understand the thermal-hydraulic behavior in the secondary side of horizontal steam generator during the plant normal operation. A test was carried out with cross section slice model simulated the straight tube region. In this paper, the results of the test is reported, and the effect of the horizontal steam generator internals on the thermalhydraulic behavior of the secondary side and the circulation characteristics of the secondary side are discussed. (orig.). 3 refs.

  5. Advanced energy utilization MHD power generation

    International Nuclear Information System (INIS)

    2008-01-01

    The 'Technical Committee on Advanced Energy Utilization MHD Power Generation' was started to establish advanced energy utilization technologies in Japan, and has been working for three years from June 2004 to May 2007. This committee investigated closed cycle MHD, open cycle MHD, and liquid metal MHD power generation as high-efficiency power generation systems on the earth. Then, aero-space application and deep space exploration technologies were investigated as applications of MHD technology. The spin-off from research and development on MHD power generation such as acceleration and deceleration of supersonic flows was expected to solve unstart phenomena in scramjet engine and also to solve abnormal heating of aircrafts by shock wave. In addition, this committee investigated researches on fuel cells, on secondary batteries, on connection of wind power system to power grid, and on direct energy conversion system from nuclear fusion reactor for future. The present technical report described results of investigations by the committee. (author)

  6. Development of advanced PWR steam generator

    International Nuclear Information System (INIS)

    Saito, Itaru; Nakamura, Tomomichi

    1999-01-01

    In response to the increased power of the advanced PWR, it is necessary to develop a steam generator (SG) which has a large capacity with high performance and high reliability as well as being economical to produce. In this paper, the development of the design of a new SG for the advanced PWRs is described and compared with the design of a conventional SG. Moreover, an outline of a seismic verification test for the U-bend tube bundle which includes advanced anti-vibration bars (AVB) which are very important is described. As a result, it was verified that the bundle has sufficient strength and a relatively high attenuation to seismic loads. These results will be reflected in the detailed design of advanced AVBs. (author)

  7. Advanced Thermoelectric Materials for Radioisotope Thermoelectric Generators

    Science.gov (United States)

    Caillat, Thierry; Hunag, C.-K.; Cheng, S.; Chi, S. C.; Gogna, P.; Paik, J.; Ravi, V.; Firdosy, S.; Ewell, R.

    2008-01-01

    This slide presentation reviews the progress and processes involved in creating new and advanced thermoelectric materials to be used in the design of new radioiootope thermoelectric generators (RTGs). In a program with Department of Energy, NASA is working to develop the next generation of RTGs, that will provide significant benefits for deep space missions that NASA will perform. These RTG's are planned to be capable of delivering up to 17% system efficiency and over 12 W/kg specific power. The thermoelectric materials being developed are an important step in this process.

  8. Next generation advanced nuclear reactor designs

    International Nuclear Information System (INIS)

    Turgut, M. H.

    2009-01-01

    Growing energy demand by technological developments and the increase of the world population and gradually diminishing energy resources made nuclear power an indispensable option. The renewable energy sources like solar, wind and geothermal may be suited to meet some local needs. Environment friendly nuclear energy which is a suitable solution to large scale demands tends to develop highly economical, advanced next generation reactors by incorporating technological developments and years of operating experience. The enhancement of safety and reliability, facilitation of maintainability, impeccable compatibility with the environment are the goals of the new generation reactors. The protection of the investment and property is considered as well as the protection of the environment and mankind. They became economically attractive compared to fossil-fired units by the use of standard designs, replacing some active systems by passive, reducing construction time and increasing the operation lifetime. The evolutionary designs were introduced at first by ameliorating the conventional plants, than revolutionary systems which are denoted as generation IV were verged to meet future needs. The investigations on the advanced, proliferation resistant fuel cycle technologies were initiated to minimize the radioactive waste burden by using new generation fast reactors and ADS transmuters.

  9. An overview of advanced power generation technologies

    International Nuclear Information System (INIS)

    Gardner, D.; Shaw, P.

    1993-01-01

    This paper is intended as a brief review of the technologies currently applied in Australian electricity generation and the technologies which are likely to be employed in the future. The paper opens with a review of the primary energy resources available for the generation of electricity in Australia, and the technologies currently employed. The development of advanced generation technologies around the world is reviewed, and the most likely technologies to be employed in Australia are described. There are a number of renewable and alternative technologies, such as generation from sewage digester, landfill or mine gases. Their impact would, however, be disproportionate because of the strong climate forcing effect of methane. Of the wide range of other emerging renewable technologies examined, solar thermal offers the best prospect of maturing into a financially-competitive technology for large scale generation in the next 20 years. However, will remain unable to compete with non-renewable technologies in normal financial terms, at least until 2005 and probably well beyond that date. Generation using the fission of nuclear fuels is a mature, proven technology. Based on the most likely fuel and other assumptions made in this study, the costs of nuclear generation are only moderately higher than conventional coal-fired options. Nuclear generation is thus a relatively low cost route to reductions in carbon dioxide emission for new plant, at $19/tonne CO 2 saved, in comparison with conventional black coal technology, and $13/tonne CO 2 compared with conventional brown coal firing. While major considerations of societal acceptance clearly exist, nuclear generation has the necessary technical and financial qualifications for serious consideration as an element in any greenhouse strategy. 5 tab., 2 figs

  10. Advanced Stirling Radioisotope Generator Life Certification Plan

    Science.gov (United States)

    Rusick, Jeffrey J.; Zampino, Edward J.

    2013-01-01

    An Advanced Stirling Radioisotope Generator (ASRG) power supply is being developed by the Department of Energy (DOE) in partnership with NASA for potential future deep space science missions. Unlike previous radioisotope power supplies for space exploration, such as the passive MMRTG used recently on the Mars Curiosity rover, the ASRG is an active dynamic power supply with moving Stirling engine mechanical components. Due to the long life requirement of 17 years and the dynamic nature of the Stirling engine, the ASRG project faced some unique challenges trying to establish full confidence that the power supply will function reliably over the mission life. These unique challenges resulted in the development of an overall life certification plan that emphasizes long-term Stirling engine test and inspection when analysis is not practical. The ASRG life certification plan developed is described.

  11. The average inter-crossing number of equilateral random walks and polygons

    International Nuclear Information System (INIS)

    Diao, Y; Dobay, A; Stasiak, A

    2005-01-01

    In this paper, we study the average inter-crossing number between two random walks and two random polygons in the three-dimensional space. The random walks and polygons in this paper are the so-called equilateral random walks and polygons in which each segment of the walk or polygon is of unit length. We show that the mean average inter-crossing number ICN between two equilateral random walks of the same length n is approximately linear in terms of n and we were able to determine the prefactor of the linear term, which is a = 3ln2/8 ∼ 0.2599. In the case of two random polygons of length n, the mean average inter-crossing number ICN is also linear, but the prefactor of the linear term is different from that of the random walks. These approximations apply when the starting points of the random walks and polygons are of a distance ρ apart and ρ is small compared to n. We propose a fitting model that would capture the theoretical asymptotic behaviour of the mean average ICN for large values of ρ. Our simulation result shows that the model in fact works very well for the entire range of ρ. We also study the mean ICN between two equilateral random walks and polygons of different lengths. An interesting result is that even if one random walk (polygon) has a fixed length, the mean average ICN between the two random walks (polygons) would still approach infinity if the length of the other random walk (polygon) approached infinity. The data provided by our simulations match our theoretical predictions very well

  12. Recent advances in RF power generation

    International Nuclear Information System (INIS)

    Tallerico, P.J.

    1990-01-01

    This paper is a review of the progress and methods used in RF generation for particle accelerators. The frequencies of interest are from a few megahertz to 100 GHz, and the powers are for super linear collider applications, but in this case the pulses are short, generally below 1 μs. The very high-power, short-pulse generators are only lightly reviewed here, and for more details the reader should follow the specialized references. Different RF generators excel over various parts of the frequency spectrum. Below 100 MHz solid-state devices and gridded tubes prevail, while the region between 400 MHz and 3 GHz, the cyclotron-resonant devices predominate, and above 250 GHz, Free-Electron Lasers and ubitrons are the most powerful generators. The emphasis for this review is on microwave generation at frequencies below 20 GHz, so the cyclotron-resonant devices are only partially reviewed, while the progress on free-electron laser and ubitrons is not reviewed in this paper. 39 refs., 4 figs

  13. Advanced On Board Inert Gas Generation System (OBBIGS), Phase II

    Data.gov (United States)

    National Aeronautics and Space Administration — Valcor Engineering Corporation proposes to develop an advanced On Board Inert Gas Generation System, OBIGGS, for aircraft fuel tank inerting to prevent hazardous...

  14. Thermal Model Predictions of Advanced Stirling Radioisotope Generator Performance

    Science.gov (United States)

    Wang, Xiao-Yen J.; Fabanich, William Anthony; Schmitz, Paul C.

    2014-01-01

    This presentation describes the capabilities of three-dimensional thermal power model of advanced stirling radioisotope generator (ASRG). The performance of the ASRG is presented for different scenario, such as Venus flyby with or without the auxiliary cooling system.

  15. Advanced On Board Inert Gas Generation System (OBBIGS), Phase I

    Data.gov (United States)

    National Aeronautics and Space Administration — Valcor Engineering Corporation proposes to develop an advanced On Board Inert Gas Generation System, OBIGGS, for aircraft fuel tank inerting to prevent hazardous...

  16. Carpet Specifiers Guide. Ultron, Advanced Generation Nylon Carpet Fiber.

    Science.gov (United States)

    Monsanto Textiles Co., Atlanta, GA.

    The purpose of this guide is to assist specifiers in properly specifying carpet made of Monsanto Ultron advanced generation nylon fiber. The guide describes a variety of conditions that should be considered in arriving at the proper selection and provides reference information and data, ranging from varying regulatory requirements, performance and…

  17. Advanced LIGO: the next generation of gravitational wave detectors

    International Nuclear Information System (INIS)

    Harry, Gregory M

    2010-01-01

    The Advanced LIGO gravitational wave detectors are next generation instruments which will replace the existing initial LIGO detectors. They are currently being constructed and installed. Advanced LIGO strain sensitivity is designed to be about a factor 10 better than initial LIGO over a broad band and usable to 10 Hz, in contrast to 40 Hz for initial LIGO. This is expected to allow for detections and significant astrophysics in most categories of gravitational waves. To achieve this sensitivity, all hardware subsystems are being replaced with improvements. Designs and expected performance are presented for the seismic isolation, suspensions, optics and laser subsystems. Possible enhancements to Advanced LIGO, either to resolve problems that may arise and/or to allow for improved performance, are now being researched. Some of these enhancements are discussed along with some potential technology being considered for detectors beyond Advanced LIGO.

  18. Advanced methodology for generation expansion planning including interconnected systems

    Energy Technology Data Exchange (ETDEWEB)

    Zhao, M.; Yokoyama, R.; Yasuda, K. [Tokyo Metropolitan Univ. (Japan); Sasaki, H. [Hiroshima Univ. (Japan); Ogimoto, K. [Electric Power Development Co. Ltd., Tokyo (Japan)

    1994-12-31

    This paper reviews advanced methodology for generation expansion planning including interconnected systems developed in Japan, putting focus on flexibility and efficiency in a practical application. First, criteria for evaluating flexibility of generation planning considering uncertainties are introduced. Secondly, the flexible generation mix problem is formulated as a multi-objective optimization with more than two objective functions. The multi-objective optimization problem is then transformed into a single objective problem by using the weighting method, to obtain the Pareto optimal solution, and solved by a dynamics programming technique. Thirdly, a new approach for electric generation expansion planning of interconnected systems is presented, based on the Benders Decomposition technique. That is, large scale generation problem constituted by the general economic load dispatch problem, and several sub problems which are composed of smaller scale isolated system generation expansion plans. Finally, the generation expansion plan solved by an artificial neural network is presented. In conclusion, the advantages and disadvantages of this method from the viewpoint of flexibility and applicability to practical generation expansion planning are presented. (author) 29 refs., 10 figs., 4 tabs.

  19. Special issue on advancing grid-connected renewable generation systems

    DEFF Research Database (Denmark)

    Blaabjerg, Frede; Yang, Yongheng

    2017-01-01

    Renewables are heavily involved in power generation, as an essential component for today’s energy paradigm. Energy structure—both national and international—has been undergoing significant changes over the past few decades. For instance, in Denmark, power generation is shifting from fossil......-fuel-based to renewable-based in terms of energy sources, from centralized to decentralized in terms of architectures, and from sole to miscellaneous in terms of energy varieties [1]. In this energy evolution, the power electronic technology plays an enabling role in the integration and advancements of renewables...

  20. Advanced Stirling Radioisotope Generator Engineering Unit 2 Anomaly Investigation

    Science.gov (United States)

    Lewandowski, Edward J.; Dobbs, Michael W.; Oriti, Salvatore M.

    2018-01-01

    The Advanced Stirling Radioisotope Generator (ASRG) Engineering Unit 2 (EU2) is the highest fidelity electrically heated Stirling radioisotope generator built to date. NASA Glenn Research Center completed the assembly of the ASRG EU2 in September 2014 using hardware from the now cancelled ASRG flight development project. The ASRG EU2 integrated the first pair of Sunpower's Advanced Stirling Convertors (ASC-E3 #1 and #2) in an aluminum generator housing with Lockheed Martin's (LM's) Engineering Development Unit (EDU) 4 controller. After just 179 hr of EU2 generator operation, the first power fluctuation occurred on ASC-E3 #1. The first power fluctuation occurred 175 hr later on ASC-E3 #2. Over time, the power fluctuations became more frequent on both convertors and larger in magnitude. Eventually the EU2 was shut down in January 2015. An anomaly investigation was chartered to determine root cause of the power fluctuations and other anomalous observations. A team with members from Glenn, Sunpower, and LM conducted a thorough investigation of the EU2 anomalies. Findings from the EU2 disassembly identified proximate causes of the anomalous observations. Discussion of the team's assessment of the primary possible failure theories, root cause, and conclusions is provided. Recommendations are made for future Stirling generator development to address the findings from the anomaly investigation. Additional findings from the investigation are also discussed.

  1. MHD generator performance analysis for the Advanced Power Train study

    Science.gov (United States)

    Pian, C. C. P.; Hals, F. A.

    1984-01-01

    Comparative analyses of different MHD power train designs for early commercial MHD power plants were performed for plant sizes of 200, 500, and 1000 MWe. The work was conducted as part of the first phase of a planned three-phase program to formulate an MHD Advanced Power Train development program. This paper presents the results of the MHD generator design and part-load analyses. All of the MHD generator designs were based on burning of coal with oxygen-enriched air preheated to 1200 F. Sensitivities of the MHD generator design performance to variations in power plant size, coal type, oxygen enrichment level, combustor heat loss, channel length, and Mach number were investigated. Basd on these sensitivity analyses, together with the overall plant performance and cost-of-electricity analyses, as well as reliability and maintenance considerations, a recommended MHD generator design was selected for each of the three power plants. The generators for the 200 MWe and 500 MWe power plant sizes are supersonic designs. A subsonic generator design was selected for the 1000 MWe plant. Off-design analyses of part-load operation of the supersonic channel selected for the 200 MWe power plant were also conductd. The results showed that a relatively high overall net plant efficiency can be maintained during part-laod operation with a supersonic generator design.

  2. Characterization of the Advanced Stirling Radioisotope Generator Engineering Unit 2

    Science.gov (United States)

    Lewandowski, Edward J.; Oriti, Salvatore M.; Schifer, Niholas A.

    2016-01-01

    Significant progress was made developing the Advanced Stirling Radioisotope Generator (ASRG) 140-W radioisotope power system. While the ASRG flight development project has ended, the hardware that was designed and built under the project is continuing to be tested to support future Stirling-based power system development. NASA Glenn Research Center recently completed the assembly of the ASRG Engineering Unit 2 (EU2). The ASRG EU2 consists of the first pair of Sunpower's Advanced Stirling Convertor E3 (ASC-E3) Stirling convertors mounted in an aluminum housing, and Lockheed Martin's Engineering Development Unit (EDU) 4 controller (a fourth-generation controller). The ASC-E3 convertors and Generator Housing Assembly (GHA) closely match the intended ASRG Qualification Unit flight design. A series of tests were conducted to characterize the EU2, its controller, and the convertors in the flight-like GHA. The GHA contained an argon cover gas for these tests. The tests included measurement of convertor, controller, and generator performance and efficiency; quantification of control authority of the controller; disturbance force measurement with varying piston phase and piston amplitude; and measurement of the effect of spacecraft direct current (DC) bus voltage on EU2 performance. The results of these tests are discussed and summarized, providing a basic understanding of EU2 characteristics and the performance and capability of the EDU 4 controller.

  3. BIOMASS GASIFICATION AND POWER GENERATION USING ADVANCED GAS TURBINE SYSTEMS

    Energy Technology Data Exchange (ETDEWEB)

    David Liscinsky

    2002-10-20

    A multidisciplined team led by the United Technologies Research Center (UTRC) and consisting of Pratt & Whitney Power Systems (PWPS), the University of North Dakota Energy & Environmental Research Center (EERC), KraftWork Systems, Inc. (kWS), and the Connecticut Resource Recovery Authority (CRRA) has evaluated a variety of gasified biomass fuels, integrated into advanced gas turbine-based power systems. The team has concluded that a biomass integrated gasification combined-cycle (BIGCC) plant with an overall integrated system efficiency of 45% (HHV) at emission levels of less than half of New Source Performance Standards (NSPS) is technically and economically feasible. The higher process efficiency in itself reduces consumption of premium fuels currently used for power generation including those from foreign sources. In addition, the advanced gasification process can be used to generate fuels and chemicals, such as low-cost hydrogen and syngas for chemical synthesis, as well as baseload power. The conceptual design of the plant consists of an air-blown circulating fluidized-bed Advanced Transport Gasifier and a PWPS FT8 TwinPac{trademark} aeroderivative gas turbine operated in combined cycle to produce {approx}80 MWe. This system uses advanced technology commercial products in combination with components in advanced development or demonstration stages, thereby maximizing the opportunity for early implementation. The biofueled power system was found to have a levelized cost of electricity competitive with other new power system alternatives including larger scale natural gas combined cycles. The key elements are: (1) An Advanced Transport Gasifier (ATG) circulating fluid-bed gasifier having wide fuel flexibility and high gasification efficiency; (2) An FT8 TwinPac{trademark}-based combined cycle of approximately 80 MWe; (3) Sustainable biomass primary fuel source at low cost and potentially widespread availability-refuse-derived fuel (RDF); (4) An overall integrated

  4. Advanced Material Strategies for Next-Generation Additive Manufacturing

    Science.gov (United States)

    Chang, Jinke; He, Jiankang; Zhou, Wenxing; Lei, Qi; Li, Xiao; Li, Dichen

    2018-01-01

    Additive manufacturing (AM) has drawn tremendous attention in various fields. In recent years, great efforts have been made to develop novel additive manufacturing processes such as micro-/nano-scale 3D printing, bioprinting, and 4D printing for the fabrication of complex 3D structures with high resolution, living components, and multimaterials. The development of advanced functional materials is important for the implementation of these novel additive manufacturing processes. Here, a state-of-the-art review on advanced material strategies for novel additive manufacturing processes is provided, mainly including conductive materials, biomaterials, and smart materials. The advantages, limitations, and future perspectives of these materials for additive manufacturing are discussed. It is believed that the innovations of material strategies in parallel with the evolution of additive manufacturing processes will provide numerous possibilities for the fabrication of complex smart constructs with multiple functions, which will significantly widen the application fields of next-generation additive manufacturing. PMID:29361754

  5. Advanced Material Strategies for Next-Generation Additive Manufacturing.

    Science.gov (United States)

    Chang, Jinke; He, Jiankang; Mao, Mao; Zhou, Wenxing; Lei, Qi; Li, Xiao; Li, Dichen; Chua, Chee-Kai; Zhao, Xin

    2018-01-22

    Additive manufacturing (AM) has drawn tremendous attention in various fields. In recent years, great efforts have been made to develop novel additive manufacturing processes such as micro-/nano-scale 3D printing, bioprinting, and 4D printing for the fabrication of complex 3D structures with high resolution, living components, and multimaterials. The development of advanced functional materials is important for the implementation of these novel additive manufacturing processes. Here, a state-of-the-art review on advanced material strategies for novel additive manufacturing processes is provided, mainly including conductive materials, biomaterials, and smart materials. The advantages, limitations, and future perspectives of these materials for additive manufacturing are discussed. It is believed that the innovations of material strategies in parallel with the evolution of additive manufacturing processes will provide numerous possibilities for the fabrication of complex smart constructs with multiple functions, which will significantly widen the application fields of next-generation additive manufacturing.

  6. Advanced Material Strategies for Next-Generation Additive Manufacturing

    Directory of Open Access Journals (Sweden)

    Jinke Chang

    2018-01-01

    Full Text Available Additive manufacturing (AM has drawn tremendous attention in various fields. In recent years, great efforts have been made to develop novel additive manufacturing processes such as micro-/nano-scale 3D printing, bioprinting, and 4D printing for the fabrication of complex 3D structures with high resolution, living components, and multimaterials. The development of advanced functional materials is important for the implementation of these novel additive manufacturing processes. Here, a state-of-the-art review on advanced material strategies for novel additive manufacturing processes is provided, mainly including conductive materials, biomaterials, and smart materials. The advantages, limitations, and future perspectives of these materials for additive manufacturing are discussed. It is believed that the innovations of material strategies in parallel with the evolution of additive manufacturing processes will provide numerous possibilities for the fabrication of complex smart constructs with multiple functions, which will significantly widen the application fields of next-generation additive manufacturing.

  7. Advanced Stirling Radioisotope Generator EU2 Anomaly Investigation

    Science.gov (United States)

    Lewandowski, Edward J.; Dobbs, Michael W.; Oriti, Salvatore M.

    2016-01-01

    The Advanced Stirling Radioisotope Generator (ASRG) Engineering Unit 2 (EU2) is the highest fidelity electrically-heated Stirling radioisotope generator built to date. NASA Glenn Research Center (GRC) completed the assembly of the ASRG EU2 in September, 2014 using hardware from the now cancelled ASRG flight development project. The ASRG EU2 integrated the first pair of Sunpower's ASC-E3 Stirling convertors (ASC-E3 #1 and #2) in an aluminum generator housing with Lockheed Martin's Engineering Development Unit (EDU) 4 controller. After just 179 hours of EU2 generator operation, the first power fluctuation occurred on ASC-E3 #1. The first power fluctuation occurred 175 hours later on ASC-E3 #2. Over time, the power fluctuations became more frequent on both convertors and larger in magnitude. Eventually the EU2 was shut down in January, 2015. An anomaly investigation was chartered to determine root cause of the power fluctuations and other anomalous observations. A team with members from GRC, Sunpower, and Lockheed Martin conducted a thorough investigation of the EU2 anomalies. Findings from the EU2 disassembly identified proximate causes of the anomalous observations. Discussion of the team's assessment of the primary possible failure theories, root cause, and conclusions is provided. Recommendations are made for future Stirling generator development to address the findings from the anomaly investigation. Additional findings from the investigation are also discussed.

  8. Characterization of the Advanced Stirling Radioisotope Generator EU2

    Science.gov (United States)

    Lewandowski, Edward J.; Oriti, Salvatore M.; Schifer, Nicholas A.

    2015-01-01

    Significant progress was made developing the Advanced Stirling Radioisotope Generator (ASRG), a 140-watt radioisotope power system. While the ASRG flight development project has ended, the hardware that was designed and built under the project is continuing to be tested to support future Stirling-based power system development. NASA GRC recently completed the assembly of the ASRG Engineering Unit 2 (EU2). The ASRG EU2 consists of the first pair of Sunpower's ASC-E3 Stirling convertors mounted in an aluminum housing, and Lockheed Martin's Engineering Development Unit (EDU) 4 controller (a fourth generation controller). The ASC-E3 convertors and Generator Housing Assembly (GHA) closely match the intended ASRG Qualification Unit flight design. A series of tests were conducted to characterize the EU2, its controller, and the convertors in the flight-like GHA. The GHA contained an argon cover gas for these tests. The tests included: measurement of convertor, controller, and generator performance and efficiency, quantification of control authority of the controller, disturbance force measurement with varying piston phase and piston amplitude, and measurement of the effect of spacecraft DC bus voltage on EU2 performance. The results of these tests are discussed and summarized, providing a basic understanding of EU2 characteristics and the performance and capability of the EDU 4 controller.

  9. ASTRID, Generation IV advanced sodium technological reactor for industrial demonstration

    International Nuclear Information System (INIS)

    Gauche, F.

    2013-01-01

    ASTRID (Advanced Sodium Technological Reactor for Industrial Demonstration) is an integrated technology demonstrator designed to demonstrate the operability of the innovative choices enabling fast neutron reactor technology to meet the Generation IV criteria. ASTRID is a sodium-cooled fast reactor with an electricity generating power of 600 MWe. In order to meet the generation IV goals, ASTRID will incorporate the following decisive innovations: -) an improved core with a very low, even negative void coefficient; -) the possible installation of additional safety devices in the core. For example, passive anti-reactivity insertion devices are explored; -) more core instrumentation; -) an energy conversion system with modular steam generators, to limit the effects of a possible sodium-water reaction, or sodium-nitrogen exchangers; -) considerable thermal inertia combined with natural convection to deal with decay heat; -)elimination of major sodium fires by bunkerization and/or inert atmosphere in the premises; -) to take into account off-site hazards (earthquake, airplane crash,...) right from the design stage; -) a complete rethink of the reactor architecture in order to limit the risk of proliferation. ASTRID will also include systems for reducing the length of refueling outages and increasing the burn-up and the duration of the cycle. In-service inspection, maintenance and repair are also taken into account right from the start of the project. The ASTRID prototype should be operational by about 2023. (A.C.)

  10. Status of advanced containment systems for next generation water reactors

    International Nuclear Information System (INIS)

    1994-06-01

    The present IAEA status report is intended to provide information on the current status and development of containment systems of the next generation reactors for electricity production and, particularly, to highlight features which may be considered advanced, i.e. which present improved performance with evolutionary or innovative design solutions or new design approaches. The objectives of the present status report are: To present, on a concise and consistent basis, selected containment designs currently being developed in the world; to review and compare new approaches to the design bases for the containments, in order to identify common trends, that may eventually lead to greater worldwide consensus, to identify, list and compare existing design objectives for advanced containments, related to safety, availability, maintainability, plant life, decommissioning, economics, etc.; to describe the general approaches adopted in different advanced containments to cope with various identified challenges, both those included in the current design bases and those related to new events considered in the design; to briefly identify recent achievements and future needs for new or improved computer codes, standards, experimental research, prototype testing, etc. related to containment systems; to describe the outstanding features of some containments or specific solutions proposed by different parties and which are generally interesting to the international scientific community. 36 refs, 27 figs, 1 tab

  11. Leakage Currents and Gas Generation in Advanced Wet Tantalum Capacitors

    Science.gov (United States)

    Teverovsky, Alexander

    2015-01-01

    Currently, military grade, established reliability wet tantalum capacitors are among the most reliable parts used for space applications. This has been achieved over the years by extensive testing and improvements in design and materials. However, a rapid insertion of new types of advanced, high volumetric efficiency capacitors in space systems without proper testing and analysis of degradation mechanisms might increase risks of failures. The specifics of leakage currents in wet electrolytic capacitors is that the conduction process is associated with electrolysis of electrolyte and gas generation resulting in building up of internal gas pressure in the parts. The risk associated with excessive leakage currents and increased pressure is greater for high value advanced wet tantalum capacitors, but it has not been properly evaluated yet. In this work, in Part I, leakages currents in various types of tantalum capacitors have been analyzed in a wide range of voltages, temperatures, and time under bias. Gas generation and the level of internal pressure have been calculated in Part II for different case sizes and different hermeticity leak rates to assess maximal allowable leakage currents. Effects related to electrolyte penetration to the glass seal area have been studied and the possibility of failures analyzed in Part III. Recommendations for screening and qualification to reduce risks of failures have been suggested.

  12. Design features of Advanced Power Reactor (APR) 1400 steam generator

    International Nuclear Information System (INIS)

    Park, Tae-Jung; Park, Jun-Soo; Kim, Moo-Yong

    2004-01-01

    Advanced Power Reactor 1400 (APR 1400) which is to achieve the improvement of the safety and economical efficiency has been developed by Korea Hydro and Nuclear Power Co., Ltd. (KHNP) with the support from industries and research institutes. The steam generator for APR 1400 is an evolutionary type from System 80 + , which is the recirculating U-tube heat exchanger with integral economizer. Compared to the System 80 + steam generator, it is focused on the improved design features, operating and design conditions of APR 1400 steam generator. Especially, from the operation experience of Korean Standard Nuclear Power Plant (KSNP) steam generator, the lessons-learned measures are incorporated to prevent the tube wear caused by flow-induced vibration (FIV). The concepts for the preventive design features against FIV are categorized to two fields; flow distribution and dynamic response characteristics. From the standpoint of flow distribution characteristics, the egg-crate flow distribution plate (EFDP) is installed to prevent the local excessive flow loaded on the most susceptible tube to wear. The parametric study is performed to select the optimum design with the efficient mitigation of local excessive flow. ATHOS3 Mod-01 is used and partly modified to analyze the flow field of the APR 1400 steam generator. In addition, the upper tube bundle support is designed to eliminate the presence of tube with a low natural frequency. Based on the improved upper tube bundle support, the modal analysis is performed and compared with that of System 80 + . Using the results of flow distribution and modal analysis, the two mechanisms of flow-induced vibration are investigated; fluid-elastic instability (FEI) and random turbulence excitation (RTE). (authors)

  13. Advanced numerical methods in mesh generation and mesh adaptation

    Energy Technology Data Exchange (ETDEWEB)

    Lipnikov, Konstantine [Los Alamos National Laboratory; Danilov, A [MOSCOW, RUSSIA; Vassilevski, Y [MOSCOW, RUSSIA; Agonzal, A [UNIV OF LYON

    2010-01-01

    Numerical solution of partial differential equations requires appropriate meshes, efficient solvers and robust and reliable error estimates. Generation of high-quality meshes for complex engineering models is a non-trivial task. This task is made more difficult when the mesh has to be adapted to a problem solution. This article is focused on a synergistic approach to the mesh generation and mesh adaptation, where best properties of various mesh generation methods are combined to build efficiently simplicial meshes. First, the advancing front technique (AFT) is combined with the incremental Delaunay triangulation (DT) to build an initial mesh. Second, the metric-based mesh adaptation (MBA) method is employed to improve quality of the generated mesh and/or to adapt it to a problem solution. We demonstrate with numerical experiments that combination of all three methods is required for robust meshing of complex engineering models. The key to successful mesh generation is the high-quality of the triangles in the initial front. We use a black-box technique to improve surface meshes exported from an unattainable CAD system. The initial surface mesh is refined into a shape-regular triangulation which approximates the boundary with the same accuracy as the CAD mesh. The DT method adds robustness to the AFT. The resulting mesh is topologically correct but may contain a few slivers. The MBA uses seven local operations to modify the mesh topology. It improves significantly the mesh quality. The MBA method is also used to adapt the mesh to a problem solution to minimize computational resources required for solving the problem. The MBA has a solid theoretical background. In the first two experiments, we consider the convection-diffusion and elasticity problems. We demonstrate the optimal reduction rate of the discretization error on a sequence of adaptive strongly anisotropic meshes. The key element of the MBA method is construction of a tensor metric from hierarchical edge

  14. Sensor-Based Trajectory Generation for Advanced Driver Assistance System

    Directory of Open Access Journals (Sweden)

    Christopher James Shackleton

    2013-03-01

    Full Text Available This paper investigates the trajectory generation problem for an advanced driver assistance system that could sense the driving state of the vehicle, so that a collision free trajectory can be generated safely. Specifically, the problem of trajectory generation is solved for the safety assessment of the driving state and to manipulate the vehicle in order to avoid any possible collisions. The vehicle senses the environment so as to obtain information about other vehicles and static obstacles ahead. Vehicles may share the perception of the environment via an inter-vehicle communication system. The planning algorithm is based on a visibility graph. A lateral repulsive potential is applied to adaptively maintain a trade-off between the trajectory length and vehicle clearance, which is the greatest problem associated with visibility graphs. As opposed to adaptive roadmap approaches, the algorithm exploits the structured nature of the environment for construction of the roadmap. Furthermore, the mostly organized nature of traffic systems is exploited to obtain orientation invariance, which is another limitation of both visibility graphs and adaptive roadmaps. Simulation results show that the algorithm can successfully solve the problem for a variety of commonly found scenarios.

  15. Bim Automation: Advanced Modeling Generative Process for Complex Structures

    Science.gov (United States)

    Banfi, F.; Fai, S.; Brumana, R.

    2017-08-01

    The new paradigm of the complexity of modern and historic structures, which are characterised by complex forms, morphological and typological variables, is one of the greatest challenges for building information modelling (BIM). Generation of complex parametric models needs new scientific knowledge concerning new digital technologies. These elements are helpful to store a vast quantity of information during the life cycle of buildings (LCB). The latest developments of parametric applications do not provide advanced tools, resulting in time-consuming work for the generation of models. This paper presents a method capable of processing and creating complex parametric Building Information Models (BIM) with Non-Uniform to NURBS) with multiple levels of details (Mixed and ReverseLoD) based on accurate 3D photogrammetric and laser scanning surveys. Complex 3D elements are converted into parametric BIM software and finite element applications (BIM to FEA) using specific exchange formats and new modelling tools. The proposed approach has been applied to different case studies: the BIM of modern structure for the courtyard of West Block on Parliament Hill in Ottawa (Ontario) and the BIM of Masegra Castel in Sondrio (Italy), encouraging the dissemination and interaction of scientific results without losing information during the generative process.

  16. Reliability Demonstration Approach for Advanced Stirling Radioisotope Generator

    Science.gov (United States)

    Ha, CHuong; Zampino, Edward; Penswick, Barry; Spronz, Michael

    2010-01-01

    Developed for future space missions as a high-efficiency power system, the Advanced Stirling Radioisotope Generator (ASRG) has a design life requirement of 14 yr in space following a potential storage of 3 yr after fueling. In general, the demonstration of long-life dynamic systems remains difficult in part due to the perception that the wearout of moving parts cannot be minimized, and associated failures are unpredictable. This paper shows a combination of systematic analytical methods, extensive experience gained from technology development, and well-planned tests can be used to ensure a high level reliability of ASRG. With this approach, all potential risks from each life phase of the system are evaluated and the mitigation adequately addressed. This paper also provides a summary of important test results obtained to date for ASRG and the planned effort for system-level extended operation.

  17. Clonal forestry, heterosis and advanced-generation breeding

    Energy Technology Data Exchange (ETDEWEB)

    Tuskan, G.A.

    1997-08-01

    This report discusses the clonal planting stock offers many advantages to the forest products industry. Advanced-generation breeding strategies should be designed to maximize within-family variance and at the same time allow the capture of heterosis. Certainly there may be a conflict in the choice of breeding strategy based on the trait of interest. It may be that the majority of the traits express heterosis due to overdominance. Alternatively, disease resistance is expressed as the lack of a specific metabolite or infection court then the homozygous recessive genotype may be the most desirable. Nonetheless, as the forest products industry begins to utilize the economic advantages of clonal forestry, breeding strategies will have to be optimized for these commercial plant materials. Here, molecular markers can be used to characterize the nature of heterosis and therefore define the appropriate breeding strategy.

  18. Distributed generation: remote power systems with advanced storage technologies

    International Nuclear Information System (INIS)

    Clark, Woodrow; Isherwood, William

    2004-01-01

    The paper discusses derived from an earlier hypothetical study of remote villiages. It considers the policy implications for communities who have their own local power resources rather than those distributed through transmission from distant sources such as dams, coal power plants or even renewables generation from wind farms, solar thermal or other resources. The issues today, post 911 and the energy crises in California, Northeast North America and Europe, signal the need for a new and different approach to energy supply(s), reliability and dissemination. Distributed generation (DG) as explored in the earlier paper appears to be one such approach that allows for local communities to become energy self-sufficient. Along with energy conservation, efficiency, and on-site generation, local power sources provide concrete definitions and understandings for heretofore ill defined concepts such as sustainability and eco-systems. The end result for any region and nation-state are 'agile energy systems' which use flexible DG, on-site generation and conservation systems meeting the needs of local communities. Now the challenge is to demonstrate and provide economic and policy structures for implementing new advanced technologies for local communities. For institutionalizing economically viable and sound environmental technologies then new finance mechanisms must be established that better reflect the true costs of clean energy distributed in local communities. For example, the aggregation of procurement contracts for on-site solar systems is far more cost effective than for each business owner, public building or household to purchase its own separate units. Thus mass purchasing contracts that are link technologies as hybrids can dramatically reduce costs. In short public-private partnerships can implement the once costly clean energy technologies into local DG systems

  19. Advanced Datapresence From A New Generation Of Research Vessels

    Science.gov (United States)

    Romsos, C. G.; Nahorniak, J.; Watkins-Brandt, K.; Bailey, D.; Reimers, C.

    2016-02-01

    The design of the next generation Regional Class Research Vessels (RCRV) for the U.S. academic research fleet includes the development of advanced datapresence systems and capabilities. Datapresence is defined here as the real-time transfer of scientific and operational data between vessel and shore, to facilitate shore-based participation in oceanographic expeditions. Datapresent technologies on the RCRVs build upon the demonstrated success of telepresence activities on satellite-connected ships. Specifically, the RCRV datapresence design integrates a broad suite of ocean and meteorological sensors on the vessel into a networked environment with satellite communication access. In addition to enabling operational decisions from shore, these capabilities will bring ocean research to the classroom and local communities, advancing ocean and atmospheric literacy, via dynamic data products that support hands-on exercises and demonstrations of oceanographic and atmospheric processes. The operational requirements of data integration, management, visualization, and user-interaction are being developed and tested now and will be refined over the next 5-6 years during the RCRV construction and transition to operations phases. This presentation will illustrate the RCRV datapresence design and how datapresent technologies will transform these National Science Foundation-owned coastal ships into continuous sampling and data streaming platforms that leverage onshore resources for making efficient scientific and operational decisions.

  20. Thermal Model Predictions of Advanced Stirling Radioisotope Generator Performance

    Science.gov (United States)

    Wang, Xiao-Yen J.; Fabanich, William Anthony; Schmitz, Paul C.

    2014-01-01

    This paper presents recent thermal model results of the Advanced Stirling Radioisotope Generator (ASRG). The three-dimensional (3D) ASRG thermal power model was built using the Thermal Desktop(trademark) thermal analyzer. The model was correlated with ASRG engineering unit test data and ASRG flight unit predictions from Lockheed Martin's (LM's) I-deas(trademark) TMG thermal model. The auxiliary cooling system (ACS) of the ASRG is also included in the ASRG thermal model. The ACS is designed to remove waste heat from the ASRG so that it can be used to heat spacecraft components. The performance of the ACS is reported under nominal conditions and during a Venus flyby scenario. The results for the nominal case are validated with data from Lockheed Martin. Transient thermal analysis results of ASRG for a Venus flyby with a representative trajectory are also presented. In addition, model results of an ASRG mounted on a Cassini-like spacecraft with a sunshade are presented to show a way to mitigate the high temperatures of a Venus flyby. It was predicted that the sunshade can lower the temperature of the ASRG alternator by 20 C for the representative Venus flyby trajectory. The 3D model also was modified to predict generator performance after a single Advanced Stirling Convertor failure. The geometry of the Microtherm HT insulation block on the outboard side was modified to match deformation and shrinkage observed during testing of a prototypic ASRG test fixture by LM. Test conditions and test data were used to correlate the model by adjusting the thermal conductivity of the deformed insulation to match the post-heat-dump steady state temperatures. Results for these conditions showed that the performance of the still-functioning inboard ACS was unaffected.

  1. The Mercury Laser Advances Laser Technology for Power Generation

    Energy Technology Data Exchange (ETDEWEB)

    Ebbers, C A; Caird, J; Moses, E

    2009-01-21

    The National Ignition Facility (NIF) at Lawrence Livermore Laboratory is on target to demonstrate 'breakeven' - creating as much fusion-energy output as laser-energy input. NIF will compress a tiny sphere of hydrogen isotopes with 1.8 MJ of laser light in a 20-ns pulse, packing the isotopes so tightly that they fuse together, producing helium nuclei and releasing energy in the form of energetic particles. The achievement of breakeven will culminate an enormous effort by thousands of scientists and engineers, not only at Livermore but around the world, during the past several decades. But what about the day after NIF achieves breakeven? NIF is a world-class engineering research facility, but if laser fusion is ever to generate power for civilian consumption, the laser will have to deliver pulses nearly 100,000 times faster than NIF - a rate of perhaps 10 shots per second as opposed to NIF's several shots a day. The Mercury laser (named after the Roman messenger god) is intended to lead the way to a 10-shots-per-second, electrically-efficient, driver laser for commercial laser fusion. While the Mercury laser will generate only a small fraction of the peak power of NIF (1/30,000), Mercury operates at higher average power. The design of Mercury takes full advantage of the technology advances manifest in its behemoth cousin (Table 1). One significant difference is that, unlike the flashlamp-pumped NIF, Mercury is pumped by highly efficient laser diodes. Mercury is a prototype laser capable of scaling in aperture and energy to a NIF-like beamline, with greater electrical efficiency, while still running at a repetition rate 100,000 times greater.

  2. Advanced Combustion Systems for Next Generation Gas Turbines

    Energy Technology Data Exchange (ETDEWEB)

    Joel Haynes; Jonathan Janssen; Craig Russell; Marcus Huffman

    2006-01-01

    Next generation turbine power plants will require high efficiency gas turbines with higher pressure ratios and turbine inlet temperatures than currently available. These increases in gas turbine cycle conditions will tend to increase NOx emissions. As the desire for higher efficiency drives pressure ratios and turbine inlet temperatures ever higher, gas turbines equipped with both lean premixed combustors and selective catalytic reduction after treatment eventually will be unable to meet the new emission goals of sub-3 ppm NOx. New gas turbine combustors are needed with lower emissions than the current state-of-the-art lean premixed combustors. In this program an advanced combustion system for the next generation of gas turbines is being developed with the goal of reducing combustor NOx emissions by 50% below the state-of-the-art. Dry Low NOx (DLN) technology is the current leader in NOx emission technology, guaranteeing 9 ppm NOx emissions for heavy duty F class gas turbines. This development program is directed at exploring advanced concepts which hold promise for meeting the low emissions targets. The trapped vortex combustor is an advanced concept in combustor design. It has been studied widely for aircraft engine applications because it has demonstrated the ability to maintain a stable flame over a wide range of fuel flow rates. Additionally, it has shown significantly lower NOx emission than a typical aircraft engine combustor and with low CO at the same time. The rapid CO burnout and low NOx production of this combustor made it a strong candidate for investigation. Incremental improvements to the DLN technology have not brought the dramatic improvements that are targeted in this program. A revolutionary combustor design is being explored because it captures many of the critical features needed to significantly reduce emissions. Experimental measurements of the combustor performance at atmospheric conditions were completed in the first phase of the program

  3. Advanced Ceramic Materials For Next-Generation Nuclear Applications

    International Nuclear Information System (INIS)

    Marra, J.

    2010-01-01

    Rising global energy demands coupled with increased environmental concerns point to one solution; they must reduce their dependence on fossil fuels that emit greenhouse gases. As the global community faces the challenge of maintaining sovereign nation security, reducing greenhouse gases, and addressing climate change nuclear power will play a significant and likely growing role. In the US, nuclear energy already provides approximately one-fifth of the electricity used to power factories, offices, homes, and schools with 104 operating nuclear power plants, located at 65 sites in 31 states. Additionally, 19 utilities have applied to the US Nuclear Regulatory Commission (NRC) for construction and operating licenses for 26 new reactors at 17 sites. This planned growth of nuclear power is occurring worldwide and has been termed the 'nuclear renaissance.' As major industrial nations craft their energy future, there are several important factors that must be considered about nuclear energy: (1) it has been proven over the last 40 years to be safe, reliable and affordable (good for Economic Security); (2) its technology and fuel can be domestically produced or obtained from allied nations (good for Energy Security); and (3) it is nearly free of greenhouse gas emissions (good for Environmental Security). Already an important part of worldwide energy security via electricity generation, nuclear energy can also potentially play an important role in industrial processes and supporting the nation's transportation sector. Coal-to-liquid processes, the generation of hydrogen and supporting the growing potential for a greatly increased electric transportation system (i.e. cars and trains) mean that nuclear energy could see dramatic growth in the near future as we seek to meet our growing demand for energy in cleaner, more secure ways. In order to address some of the prominent issues associated with nuclear power generation (i.e., high capital costs, waste management, and

  4. Second Generation Advanced Reburning for High Efficiency NOx Control

    Energy Technology Data Exchange (ETDEWEB)

    Vladimir M. Zamansky; Peter M. Maly; Vitali V. Lissianski; Mark S. Sheldon; David Moyeda; Roy Payne

    2001-06-30

    This project develops a family of novel Second Generation Advanced Reburning (SGAR) NO{sub x} control technologies, which can achieve 95% NO{sub x} control in coal fired boilers at a significantly lower cost than Selective Catalytic Reduction (SCR). The conventional Advanced Reburning (AR) process integrates basic reburning and N-agent injection. The SGAR systems include six AR variants: (1) AR-Lean--injection of the N-agent and promoter along with overfire air; (2) AR-Rich--injection of N-agent and promoter into the reburning zone; (3) Multiple Injection Advanced Reburning (MIAR)--injection of N-agents and promoters both into the reburning zone and with overfire air; (4) AR-Lean + Promoted SNCR--injection of N-agents and promoters with overfire air and into the temperature zone at which Selective Non-Catalytic Reduction (SNCR) is effective; (5) AR-Rich + Promoted SNCR--injection of N-agents and promoters into the reburning zone and into the SNCR zone; and (6) Promoted Reburning + Promoted SNCR--basic or promoted reburning followed by basic or promoted SNCR process. The project was conducted in two phases over a five-year period. The work included a combination of analytical and experimental studies to confirm the process mechanisms, identify optimum process configurations, and develop a design methodology for full-scale applications. Phase I was conducted from October, 1995 to September, 1997 and included both analytical studies and tests in bench and pilot-scale test rigs. Phase I moved AR technology to Maturity Level III-Major Subsystems. Phase II is conducted over a 45 month period (October, 1997-June, 2001). Phase II included evaluation of alternative promoters, development of alternative reburning fuel and N-Agent jet mixing systems, and scale up. The goal of Phase II was to move the technology to Maturity Level I-Subscale Integrated System. Tests in combustion facility ranging in firing rate from 0.1 x 10{sup 6} to 10 x 10{sup 6} Btu/hr demonstrated the

  5. Second Generation Advanced Reburning for High Efficiency NOx Control

    International Nuclear Information System (INIS)

    Zamansky, Vladimir M.; Maly, Peter M.; Sheldon, Mark; Seeker, W. Randall; Folsom, Blair A.

    1997-01-01

    Energy and Environmental Research Corporation is developing a family of high efficiency and low cost NO x control technologies for coal fired utility boilers based on Advanced Reburning (AR), a synergistic integration of basic reburning with injection of an N-agent. In conventional AR, injection of the reburn fuel is followed by simultaneous N-agent and overfire air injection. The second generation AR systems incorporate several components which can be used in different combinations. These components include: (1) Reburning Injection of the reburn fuel and overfire air. (2) N-agent Injection The N-agent (ammonia or urea) can be injected at different locations: into the reburning zone, along with the overfire air, and downstream of the overfire air injection. (3) N-agent Promotion Several sodium compounds can considerably enhance the NO x control from N-agent injection. These ''promoters'' can be added to aqueous N-agents. (4) Two Stages of N-agent Injection and Promotion Two N-agents with or without promoters can be injected at different locations for deeper NO x control. AR systems are intended for post-RACT applications in ozone non-attainment areas where NO x control in excess of 80% is required. AR will provide flexible installations that allow NO x levels to be lowered when regulations become more stringent. The total cost of NO x control for AR systems is approximately half of that for SCR. Experimental and kinetic modeling results for development of these novel AR systems are presented. Tests have been conducted in a 1.0 MMBtu/hr Boiler Simulator Facility with coal as the main fuel and natural gas as the reburning fuel. The results show that high efficiency NO x control, in the range 84-95%, can be achieved with various elements of AR. A comparative byproduct emission study was performed to compare the emissions from different variants of AR with commercial technologies (reburning and SNCR). For each technology sampling included: CO, SO 2 , N 2 O, total

  6. Advanced Virgo: a second-generation interferometric gravitational wave detector

    NARCIS (Netherlands)

    Acernese, F.; Bulten, H.J.; Rabeling, D.S.; van den Brand, J.F.J.

    2015-01-01

    Advanced Virgo is the project to upgrade the Virgo interferometric detector of gravitational waves, with the aim of increasing the number of observable galaxies (and thus the detection rate) by three orders of magnitude. The project is now in an advanced construction phase and the assembly and

  7. Advanced Virgo: a second-generation interferometric gravitational wave detector

    International Nuclear Information System (INIS)

    Acernese, F; Barone, F; Agathos, M; Agatsuma, K; Bauer, Th S; Beker, M G; Aisa, D; Allemandou, N; Allocca, A; Amarni, J; Baronick, J-P; Barsuglia, M; Astone, P; Basti, F; Balestri, G; Ballardin, G; Bavigadda, V; Basti, A; Bejger, M; Belczynski, C

    2015-01-01

    Advanced Virgo is the project to upgrade the Virgo interferometric detector of gravitational waves, with the aim of increasing the number of observable galaxies (and thus the detection rate) by three orders of magnitude. The project is now in an advanced construction phase and the assembly and integration will be completed by the end of 2015. Advanced Virgo will be part of a network, alongside the two Advanced LIGO detectors in the US and GEO HF in Germany, with the goal of contributing to the early detection of gravitational waves and to opening a new window of observation on the universe. In this paper we describe the main features of the Advanced Virgo detector and outline the status of the construction. (paper)

  8. Grid Monitoring and Advanced Control of Distributed Power Generation Systems

    DEFF Research Database (Denmark)

    Timbus, Adrian Vasile

    and adding more features to the control of distributed power generation systems (DPGS) arises. As a consequence, this thesis focuses on grid monitoring methods and possible approaches in control in order to obtain a more reliable and  exible power generation system during normal and faulty grid conditions......The movement towards a clean technology for energy production and the constraints in reducing the CO2 emissions are some factors facilitating the growth of distributed power generation systems based on renewable energy resources. Consequently, large penetration of distributed generators has been...... reported in some countries creating concerns about power system stability. This leads to a continuous evolution of grid interconnection requirements towards a better controllability of generated power and an enhanced contribution of distributed power generation systems to power system stability...

  9. Grid Monitoring and Advanced Control of Distributed Power Generation Systems

    OpenAIRE

    Timbus, Adrian Vasile

    2007-01-01

    The movement towards a clean technology for energy production and the constraints in reducing the CO2 emissions are some factors facilitating the growth of distributed power generation systems based on renewable energy resources. Consequently, large penetration of distributed generators has been reported in some countries creating concerns about power system stability. This leads to a continuous evolution of grid interconnection requirements towards a better controllability of generated power...

  10. Advanced feed water distributing system for WWER 440 steam generators

    International Nuclear Information System (INIS)

    Matal, O.; Klinga, J.; Grazl, K.; Tischler, J.; Mihalik, M.

    1995-01-01

    The original designed feed water distributing system was replaced by an advanced one. The characteristics of both feed water distributing systems have been measured and evaluated. The paper deals with the problems of measurement and evaluation of both feed water distributing system characteristics and comparison of statistical data obtained. (orig.)

  11. Advanced feed water distributing system for WWER 440 steam generators

    Energy Technology Data Exchange (ETDEWEB)

    Matal, O.; Klinga, J. [Energovyzkum Ltd, Brno (Switzerland); Grazl, K. [Vitkovice s.c., Ostrava (Switzerland); Tischler, J.; Mihalik, M. [SEP Atomove Elektrarne Bohunice (Slovakia)

    1995-12-31

    The original designed feed water distributing system was replaced by an advanced one. The characteristics of both feed water distributing systems have been measured and evaluated. The paper deals with the problems of measurement and evaluation of both feed water distributing system characteristics and comparison of statistical data obtained. (orig.). 3 refs.

  12. Advanced satellite concepts for future generation VSAT networks

    Science.gov (United States)

    Naderi, F. Michael; Wu, William W.

    1988-01-01

    Advanced communication networks that use very-small-aperture terminals (VSATs) are considered. The techniques and technologies suitable for powerful satellites and system architectures for future VSAT networks are discussed. These include high effective isotropic radiated power, multiple-beam satellite antennas, and various access techniques. Examples of systems planned by the government and private industry are described.

  13. Electric power systems advanced forecasting techniques and optimal generation scheduling

    CERN Document Server

    Catalão, João P S

    2012-01-01

    Overview of Electric Power Generation SystemsCláudio MonteiroUncertainty and Risk in Generation SchedulingRabih A. JabrShort-Term Load ForecastingAlexandre P. Alves da Silva and Vitor H. FerreiraShort-Term Electricity Price ForecastingNima AmjadyShort-Term Wind Power ForecastingGregor Giebel and Michael DenhardPrice-Based Scheduling for GencosGovinda B. Shrestha and Songbo QiaoOptimal Self-Schedule of a Hydro Producer under UncertaintyF. Javier Díaz and Javie

  14. Advancing Next-Generation Energy in Indian Country (Fact Sheet)

    Energy Technology Data Exchange (ETDEWEB)

    2012-08-01

    This fact sheet provides information on the Alaska Native governments selected to receive assistance from the Strategic Technical Assistance Response Team (START) Program, a U.S. Department of Energy Office of Indian Energy Policy and Programs (DOE-IE) initiative to provide technical expertise to support the development of next-generation energy projects in Indian Country.

  15. Primary electric power generation systems for advanced-technology engines

    Science.gov (United States)

    Cronin, M. J.

    1983-01-01

    The advantages of the all electric airplane are discussed. In the all electric airplane the generator is the sole source of electric power; it powers the primary and secondary flight controls, the environmentals, and the landing gear. Five candidates for all electric power systems are discussed and compared. Cost benefits of the all electric airplane are discussed.

  16. Recent advances in hydrogen generation, distribution and control at Westinghouse

    International Nuclear Information System (INIS)

    Tsai, S.S.; Liparulo, N.J.; Srinivas, V.; Monty, B.S.

    1989-01-01

    This paper reports that since the TMI-2 accident, Westinghouse has been actively involved in an industry-wide effort to address the hydrogen issue. Westinghouse has developed and licensed the CLASIX and CLASIX-3 codes to utilities which own the PWR ice condenser plants and BWR Mark III plants. These utilities have used these codes to perform analyses to support a hydrogen mitigation system required by the NRC hydrogen control rule, 20CFR50.44. Lately, Westinghouse has made significant advances in the hydrogen control analysis method. The hydrogen control analysis methods newly developed by Westinghouse include: a fog inerting model; a detailed equipment survivability analysis model and criteria for survivability assessment; flame temperature criteria for air/steam/hydrogen mixtures; COMPACT: an advanced computer program for analysis of hydrogen behavior in containment and containment vent system. A methodology based on these analysis methods has been developed by Westinghouse to address all the hydrogen issues, including containment integrity during and after hydrogen burns, hydrogen detonation, potential for fog inerting, and equipment survivability

  17. Advanced pulse generator and preamplifier for the HELEN laser

    Science.gov (United States)

    Norman, Michael J.; Harvey, E. J.; Hopps, N. W.; Nolan, J. R.; Smith, W. F. E.

    1997-12-01

    A replacement for the HELEN laser has been proposed that would involve a considerable increase in performance up to 100 TW from 32 beams. The design for the new laser is to be based on the technology being developed for the US National Ignition Facility. The pulse generation and preamplification stages employ novel technologies and represent a significant departure from previous designs. As part of the laser replacement development program a pulse generator and preamplifier have been built and installed on the HELEN laser at AWE, based on those employed on the Beamlet laser physics demonstration facility at Lawrence Livermore National Laboratory. As well as providing experience of the technologies involved, this system represents a significant enhancement of the performance of HELEN. Initial pulses are generated by a diode-pumped Q-switched Neodymium-doped Yttrium Lithium Fluoride ring oscillator. These are then launched into optical fiber and transported to a series of two integrated optics amplitude modulators for pulse shaping. The resulting pulses are then transported by optical fibers to a ring regenerative preamplifier for amplification to a level suitable for input to the HELEN laser. We describe this system, its performance and the enhanced capabilities of the HELEN laser resulting from its installation.

  18. Recent Advances in Second Generation Ethanol Production by Thermophilic Bacteria

    Directory of Open Access Journals (Sweden)

    Sean Michael Scully

    2014-12-01

    Full Text Available There is an increased interest in using thermophilic bacteria for the production of bioethanol from complex lignocellulosic biomass due to their higher operating temperatures and broad substrate range. This review focuses upon the main genera of thermophilic anaerobes known to produce ethanol, their physiology, and the relevance of various environmental factors on ethanol yields including the partial pressure of hydrogen, ethanol tolerance, pH and substrate inhibition. Additionally, recent development in evolutionary adaptation and genetic engineering of thermophilic bacteria is highlighted. Recent developments in advanced process techniques used for ethanol production are reviewed with an emphasis on the advantages of using thermophilic bacteria in process strategies including separate saccharification and fermentation, simultaneous saccharification and fermentation (SSF, and consolidated bioprocessing (CBP.

  19. Next Generation Risk Assessment: Incorporation of Recent Advances in Molecular, Computational, and Systems Biology (Final Report)

    Science.gov (United States)

    EPA announced the release of the final report, Next Generation Risk Assessment: Incorporation of Recent Advances in Molecular, Computational, and Systems Biology. This report describes new approaches that are faster, less resource intensive, and more robust that can help ...

  20. Advanced evolutionary phase of a first-generation star

    International Nuclear Information System (INIS)

    Eryurt-Ezer, D.

    1981-01-01

    The theoretical evolution of a first-generation star of 3Msub(sun) after the core helium-exhaustion phase has been investigated. The star displays the character of a double shell burning model. Shell hydrogen-burning produces energy mostly by the p-p chain reaction. CN-cycle reaction is only operating in the inner edge regions where sufficient amount of carbon is formed by the 3α-reactions. Hence, the shell burning time of the star is longer than that of normal stars, thus lengthening the total evolutionary lifetime of the first-generation stars. Prior to carbon-burning phase, the mass of the complete hydrogen-exhausted region is 1.14Msub(sun) and that of complete helium-exhausted region is 0.83Msub(sun). A carbon-oxygen core of about 0.87Msub(sun) has developed within the star in which the ratio of carbon to oxygen is about 0.85, but decreases down to a value of 0.50 near the boundary of the core. (orig.)

  1. Neurogenetics: advancing the "next-generation" of brain research.

    Science.gov (United States)

    Zoghbi, Huda Y; Warren, Stephen T

    2010-10-21

    There can be little doubt that genetics has transformed our understanding of mechanisms mediating brain disorders. The last two decades have brought tremendous progress in terms of accurate molecular diagnoses and knowledge of the genes and pathways that are involved in a large number of neurological and psychiatric disorders. Likewise, new methods and analytical approaches, including genome array studies and "next-generation" sequencing technologies, are bringing us deeper insights into the subtle complexities of the genetic architecture that determines our risks for these disorders. As we now seek to translate these discoveries back to clinical applications, a major challenge for the field will be in bridging the gap between genes and biology. In this Overview of Neuron's special review issue on neurogenetics, we reflect on progress made over the last two decades and highlight the challenges as well as the exciting opportunities for the future. Copyright © 2010 Elsevier Inc. All rights reserved.

  2. U.S. Advanced Materials Development Program for steam generators

    International Nuclear Information System (INIS)

    Patriarca, P.; Harkness, S.D.; Duke, J.M.

    1975-01-01

    The selection of construction materials for LMFBR steam generators is reviewed, presenting the advantages and limitations of 2 1 / 2 Cr-1 Mo steel selected for the Clinch River Breeder Reactor Plant. These limitations indicate that further development of high-strength ferritic steels containing 9 to 12 percent Cr and the high-nickel Alloy 800 could lead to superior materials, and programs to develop these materials have been started. Combustion Engineering has surveyed the experience with the high-strength ferritic steels and prepared ingots of 26 selected compositions. Charpy V-notch tests and metallography have been used to characterize these alloys, and optimum welding rod compositions for these alloys are under development. Westinghouse-Tampa is undertaking a program to gain code acceptance of Alloy 800. A program has been set up to provide the information required for design, justification, and fabrication of reliable components. Progress has been made on characterization, the role of tertiary creep in failure, and the development of welding processes. (U.S.)

  3. Advanced chemical oxygen iodine lasers for novel beam generation

    Science.gov (United States)

    Wu, Kenan; Zhao, Tianliang; Huai, Ying; Jin, Yuqi

    2018-03-01

    Chemical oxygen iodine laser, or COIL, is an impressive type of chemical laser that emits high power beam with good atmospheric transmissivity. Chemical oxygen iodine lasers with continuous-wave plane wave output are well-developed and are widely adopted in directed energy systems in the past several decades. Approaches of generating novel output beam based on chemical oxygen iodine lasers are explored in the current study. Since sophisticated physical processes including supersonic flowing of gaseous active media, chemical reacting of various species, optical power amplification, as well as thermal deformation and vibration of mirrors take place in the operation of COIL, a multi-disciplinary model is developed for tracing the interacting mechanisms and evaluating the performance of the proposed laser architectures. Pulsed output mode with repetition rate as high as hundreds of kHz, pulsed output mode with low repetition rate and high pulse energy, as well as novel beam with vector or vortex feature can be obtained. The results suggest potential approaches for expanding the applicability of chemical oxygen iodine lasers.

  4. Advanced Stirling Radioisotope Generator (ASRG) Thermal Power Model in MATLAB

    Science.gov (United States)

    Wang, Xiao-Yen, J.

    2012-01-01

    This paper presents a one-dimensional steady-state mathematical thermal power model of the ASRG. It aims to provide a guideline of understanding how the ASRG works and what can change its performance. The thermal dynamics and energy balance of the generator is explained using the thermal circuit of the ASRG. The Stirling convertor performance map is used to represent the convertor. How the convertor performance map is coupled in the thermal circuit is explained. The ASRG performance characteristics under i) different sink temperatures and ii) over the years of mission (YOM) are predicted using the one-dimensional model. Two Stirling converter control strategies, i) fixing the hot-end of temperature of the convertor by adjusting piston amplitude and ii) fixing the piston amplitude, were tested in the model. Numerical results show that the first control strategy can result in a higher system efficiency than the second control strategy when the ambient gets warmer or the general-purpose heat source (GPHS) fuel load decays over the YOM. The ASRG performance data presented in this paper doesn't pertain to the ASRG flight unit. Some data of the ASRG engineering unit (EU) and flight unit that are available in public domain are used in this paper for the purpose of numerical studies.

  5. Ford ETX-II - a second generation advanced AC propulsion system

    Energy Technology Data Exchange (ETDEWEB)

    Bates, B.; Stokes, G.P.; Ciccarelli, M.F.

    1989-02-01

    Improvements in the range and performance, and reductions in the cost, will help accelerate market acceptance of electric vehicles. Advancing the technology of the electric propulsion system is the key to improving these important electric vehicle characteristics. The Ford Motor Company is well along on a research and development program, supported by the US Department of Energy's Electric and Hybrid Vehicles Program, to develop a second generation advanced electric vehicle propulsion system suitable for use in a small commercial van.

  6. Development of Kinetic Mechanisms for Next-Generation Fuels and CFD Simulation of Advanced Combustion Engines

    Energy Technology Data Exchange (ETDEWEB)

    Pitz, William J. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); McNenly, Matt J. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Whitesides, Russell [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Mehl, Marco [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Killingsworth, Nick J. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Westbrook, Charles K. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)

    2015-12-17

    Predictive chemical kinetic models are needed to represent next-generation fuel components and their mixtures with conventional gasoline and diesel fuels. These kinetic models will allow the prediction of the effect of alternative fuel blends in CFD simulations of advanced spark-ignition and compression-ignition engines. Enabled by kinetic models, CFD simulations can be used to optimize fuel formulations for advanced combustion engines so that maximum engine efficiency, fossil fuel displacement goals, and low pollutant emission goals can be achieved.

  7. Advances in Parallelization for Large Scale Oct-Tree Mesh Generation

    Science.gov (United States)

    O'Connell, Matthew; Karman, Steve L.

    2015-01-01

    Despite great advancements in the parallelization of numerical simulation codes over the last 20 years, it is still common to perform grid generation in serial. Generating large scale grids in serial often requires using special "grid generation" compute machines that can have more than ten times the memory of average machines. While some parallel mesh generation techniques have been proposed, generating very large meshes for LES or aeroacoustic simulations is still a challenging problem. An automated method for the parallel generation of very large scale off-body hierarchical meshes is presented here. This work enables large scale parallel generation of off-body meshes by using a novel combination of parallel grid generation techniques and a hybrid "top down" and "bottom up" oct-tree method. Meshes are generated using hardware commonly found in parallel compute clusters. The capability to generate very large meshes is demonstrated by the generation of off-body meshes surrounding complex aerospace geometries. Results are shown including a one billion cell mesh generated around a Predator Unmanned Aerial Vehicle geometry, which was generated on 64 processors in under 45 minutes.

  8. Advanced Direct-Drive Generator for Improved Availability of Oscillating Wave Surge Converter Power Generation Systems Final Technical Report

    Energy Technology Data Exchange (ETDEWEB)

    Englebretson, Steven [ABB Inc., Cary, NC (United States); Ouyang, Wen [ABB Inc., Cary, NC (United States); Tschida, Colin [ABB Inc., Cary, NC (United States); Carr, Joseph [ABB Inc., Cary, NC (United States); Ramanan, V.R. [ABB Inc., Cary, NC (United States); Johnson, Matthew [Texas A& M Univ., College Station, TX (United States); Gardner, Matthew [Texas A& M Univ., College Station, TX (United States); Toliyat, Hamid [Texas A& M Univ., College Station, TX (United States); Staby, Bill [Resolute Marine Energy, Inc., Boston, MA (United States); Chertok, Allan [Resolute Marine Energy, Inc., Boston, MA (United States); Hazra, Samir [ABB Inc., Cary, NC (United States); Bhattacharya, Subhashish [ABB Inc., Cary, NC (United States)

    2017-05-13

    This report summarizes the activities conducted under the DOE-EERE funded project DE-EE0006400, where ABB Inc. (ABB), in collaboration with Texas A&M’s Advanced Electric Machines & Power Electronics (EMPE) Lab and Resolute Marine Energy (RME) designed, derisked, developed, and demonstrated a novel magnetically geared electrical generator for direct-drive, low-speed, high torque MHK applications The project objective was to investigate a novel and compact direct-drive electric generator and its system aspects that would enable elimination of hydraulic components in the Power Take-Off (PTO) of a Marine and Hydrokinetic (MHK) system with an oscillating wave surge converter (OWSC), thereby improving the availability of the MHK system. The scope of this project was limited to the development and dry lab demonstration of a low speed generator to enable future direct drive MHK systems.

  9. Advanced structures for grid Synchronization of power converters in distributed generation applications

    DEFF Research Database (Denmark)

    Luna, A.; Rocabert, J.; Candela, I.

    2012-01-01

    The Transmission System Operators are specially concerned about the Low Voltage Ride Through requirements of distributed generation power plants. Solutions based on the installation of STATCOMs and DVRs, as well as on advanced control functionalities for the existing power converters have contrib...

  10. 2D automatic body-fitted structured mesh generation using advancing extraction method

    Science.gov (United States)

    This paper presents an automatic mesh generation algorithm for body-fitted structured meshes in Computational Fluids Dynamics (CFD) analysis using the Advancing Extraction Method (AEM). The method is applicable to two-dimensional domains with complex geometries, which have the hierarchical tree-like...

  11. Toward a new generation of low-loss mirrors for the advanced gravitational waves interferometers.

    Science.gov (United States)

    Pinard, L; Sassolas, B; Flaminio, R; Forest, D; Lacoudre, A; Michel, C; Montorio, J L; Morgado, N

    2011-04-15

    The new generation of advanced interferometer needs fused silica mirrors having better optical and mechanical properties. This Letter describes the way to reduce the ion beam sputtering coating absorption at 1064 nm and to improve the layer thickness uniformity in order to coat two large mirrors (diameter 35 cm) at the same time.

  12. The design of Advanced Generation of event-base Emergency Operating Procedures

    International Nuclear Information System (INIS)

    Niwa, Yuji; Hollnagel, E.

    2000-01-01

    The system that can convert from the knowledge model (called semantic model) of operators in nuclear power plants to the intermediate database for the computerised presentation for emergency operating procedure is designed. This system is called Advanced Generation of Emergency Operating Procedure (AGEOP). The primary AGEOP system has been installed. In principle, once users specify a goal to be attained, then the system searches all paths of tasks to the specified goal. It converts the syntactical model automatically. Furthermore, considering the maintenance of emergency operating procedures that is the main purpose of developing of the system, the principle design of the Integrated Computerised Procedure Presentation (ICPP) system has been also implemented that consists of five utilities and the kernel; it means the KERNEL function of advanced generation of emergency operating procedure. The ICPP system works of highly advanced EOP maintenance. (author)

  13. The Importance of Intergenerational Communication in Advance Care Planning: Generational Relationships among Perceptions and Beliefs.

    Science.gov (United States)

    Freytag, Jennifer; Rauscher, Emily A

    2017-06-01

    This study explores triadic intergenerational perceptions of family members' beliefs and behaviors that often impact an individual's willingness to engage in advance care planning. Using data from 189 triads of young adults, their parents, and their grandparents, we examined generational relationships among individuals' openness about death, death anxiety, knowledge of surrogate decision-making, and advance care planning self-efficacy. Results of this study found significant relationships between grandparents and parents, as well as between parents and children for all variables except self-efficacy. Additionally, results of this study found indirect relationships between grandparents and their grandchildren for three variables. These findings underscore the need to treat advance care planning as a family communication issue. Implications for how advance care planning should be approached in conversations with healthcare providers and within the family are discussed.

  14. Estimation, comparison, and evaluation of advanced fission power reactor generation costs

    International Nuclear Information System (INIS)

    Waddell, J.D.

    1977-01-01

    The study compares the high-temperature gas-cooled reactor (HTGR), the gas-cooled fast reactor (GCFR), the molten-salt breeder reactor (MSBR), the light water breeder reactor (LWBR), and the heavy water reactor (HWR) with proposed light water reactors (LWR) and liquid-metal fast breeder reactors (LMFBR). The relative electrical generation costs, including the effects of the introduction of advanced reactor fuel cycles into the U.S. nuclear power economy, were projected through the year 2030. The study utilized the NEEDS computer code which is a simulation of the U.S. nuclear power economy. The future potential electrical generation costs and cumulative consumption of uranium ore were developed using characterizations of the advanced systems. The reactor-fuel cycle characterizations were developed from literature reviews and personal discussions with the proponents of the various systems. The study developed a ranking of the concepts based on generation costs and uranium consumption

  15. Multiple Access Techniques for Next Generation Wireless: Recent Advances and Future Perspectives

    Directory of Open Access Journals (Sweden)

    Shree Krishna Sharma

    2016-01-01

    Full Text Available The advances in multiple access techniques has been one of the key drivers in moving from one cellular generation to another. Starting from the first generation, several multiple access techniques have been explored in different generations and various emerging multiplexing/multiple access techniques are being investigated for the next generation of cellular networks. In this context, this paper first provides a detailed review on the existing Space Division Multiple Access (SDMA related works. Subsequently, it highlights the main features and the drawbacks of various existing and emerging multiplexing/multiple access techniques. Finally, we propose a novel concept of clustered orthogonal signature division multiple access for the next generation of cellular networks. The proposed concept envisions to employ joint antenna coding in order to enhance the orthogonality of SDMA beams with the objective of enhancing the spectral efficiency of future cellular networks.

  16. Alternative Green Technology for Power Generation Using Waste-Heat Energy And Advanced Thermoelectric Materials, Phase II

    Data.gov (United States)

    National Aeronautics and Space Administration — NASA is interested in advancing green technology research for achieving sustainable and environmentally friendly energy sources. Thermo-electric power generation...

  17. Potential use of dry cooling in support of advanced energy generation systems

    Energy Technology Data Exchange (ETDEWEB)

    Mayer, D.W.; Arnold, E.M.; Allemann, R.T.

    1979-09-01

    Advanced energy technologies were investigated for filling the energy supply and demand gap, including fuel cells, thermionic converters, and fusion. Technologies that have the potential for supplying energy in the future are solar, geothermal, coal gasification and liquefaction, clean solid fuel from coal, and oil shale. Results are presented of an analysis of the advanced energy generation systems, the potential for using dry cooling, and the waste heat generation characteristics of the advanced technologies. The magnitude of the waste heat expected to be generated indicates the following percentages of total cooling requirements would be needed by advanced energy technologies: (a) 1% to 2% in 1985, (b) 17% to 40% in 2000, and (c) 24% to 76% in 2025. Dry cooling could be required for flashed steam and dry steam geothermal plants if balancing withdrawal and reinjection of the geothermal fluid becomes a requirement. Binary cycle geothermal plants and plants using the hot dry rocks geothermmal resource are even more likely to require dry cooling since these plants will need an outside source of water. Solar central tower plants have a high potential for the use of dry cooling since they are likely to be located in the Southwest where water availability problems are already apparent. The high water consumption associated with the projected synthetic fuel production levels indicates that dry cooling will be desirable, perhaps even mandatory, to achieve a high level of synthetic fuel production. In the year 2000, between 2.5 and 13 GW of electrical energy produced by advanced power generation systems may require dry cooling. In the year 2025, this requirement may increase to between 4.5 and 81 GW/sub e/.

  18. Advanced Electron Beam Ion Sources (EBIS) for 2-nd generation carbon radiotherapy facilities

    CERN Document Server

    Shornikov, A.

    2016-01-01

    In this work we analyze how advanced Electron Beam Ion Sources (EBIS) can facilitate the progress of carbon therapy facilities. We will demonstrate that advanced ion sources enable operation of 2-nd generation ion beam therapy (IBT) accelerators. These new accelerator concepts with designs dedicated to IBT provide beams better suited for therapy and, are more cost efficient than contemporary IBT facilities. We will give a sort overview of the existing new IBT concepts and focus on those where ion source technology is the limiting factor. We will analyse whether this limitation can be overcome in the near future thanks to ongoing EBIS development.

  19. 2D automatic body-fitted structured mesh generation using advancing extraction method

    Science.gov (United States)

    Zhang, Yaoxin; Jia, Yafei

    2018-01-01

    This paper presents an automatic mesh generation algorithm for body-fitted structured meshes in Computational Fluids Dynamics (CFD) analysis using the Advancing Extraction Method (AEM). The method is applicable to two-dimensional domains with complex geometries, which have the hierarchical tree-like topography with extrusion-like structures (i.e., branches or tributaries) and intrusion-like structures (i.e., peninsula or dikes). With the AEM, the hierarchical levels of sub-domains can be identified, and the block boundary of each sub-domain in convex polygon shape in each level can be extracted in an advancing scheme. In this paper, several examples were used to illustrate the effectiveness and applicability of the proposed algorithm for automatic structured mesh generation, and the implementation of the method.

  20. The importance of collaboration in the advancement of current and next generation reactors

    International Nuclear Information System (INIS)

    Jackson, Kate; Goossen, John; Anness, Mike; Meston, Tom

    2010-01-01

    The sections of the contribution are as follows: Tradition of innovation. Growing demand for nuclear power; Collaboration drivers; Responses. Knowledge transfer and management is critical. What kind of focus? Equipment reliability. Advanced repair, replacement and construction approaches. Materials. Plant safety margins. Spent fuel management. Examples of European collaboration. Zorita materials examination. Collaboration in the development of next generation reactors; Westinghouse R and D priorities; A look to the future. (P.A.)

  1. The role of advanced technology in the future of the power generation industry

    Energy Technology Data Exchange (ETDEWEB)

    Bechtel, T.F.

    1994-10-01

    This presentation reviews the directions that technology has given the power generation industry in the past and how advanced technology will be the key for the future of the industry. The topics of the presentation include how the industry`s history has defined its culture, how today`s economic and regulatory climate has constrained its strategy, and how certain technology options might give some of the players an unfair advantage.

  2. Advanced glycation end products enhance reactive oxygen and nitrogen species generation in neutrophils in vitro.

    Science.gov (United States)

    Bansal, Savita; Siddarth, Manushi; Chawla, Diwesh; Banerjee, Basu D; Madhu, S V; Tripathi, Ashok K

    2012-02-01

    Increased oxidative stress (OS) in diabetes mellitus is one of the major factors leading to diabetic pathology. However, the mediators and mechanism that provoke OS in diabetes is not fully understood, and it is possible that accumulation of advanced glycation end products (AGEs) formed secondary to hyperglycemic conditions may incite circulating polymorphonuclear neutrophils (PMN) to generate reactive oxygen species (ROS). In this report, we aim to investigate the effect of AGE on reactive oxygen and nitrogen species generation and subsequent OS in PMN. AGE-HSA exert dose- and time-dependent enhancement of ROS and reactive nitrogen intermediates (RNI) generation by PMN. Increased ROS and RNI generation were found to be mediated through the upregulation of NADPH oxidase and inducible nitric oxide synthase (iNOS), respectively, as evident from the fact that AGE-treated neutrophils failed to generate ROS and RNI in presence of diphenyleneiodonium, a flavoprotein inhibitor for both enzymes. Further increased generation of ROS and RNI ceased when the cells were incubated with anti-RAGE antibody suggesting the involvement of AGE-RAGE interaction. Also increased malondialdehyde (MDA) and protein carbonyl formation in AGE-exposed PMN suggest induction of OS by AGE. This study provides evidence that AGEs may play a key role in the induction of oxidative stress through the augmentation of PMN-mediated ROS and RNI generation and this may be in part responsible for development of AGE-induced diabetic pathology.

  3. Design of a Facility to Test the Advanced Stirling Radioisotope Generator Engineering Unit

    Science.gov (United States)

    Lewandowski, Edward J.; Schreiber, Jeffrey G.; Oriti, Salvatore M.; Meer, David W.; Brace, Michael H.; Dugala, Gina

    2009-01-01

    The Advanced Stirling Radioisotope Generator (ASRG) is being considered to power deep space missions. An engineering unit, the ASRG-EU, was designed and fabricated by Lockheed Martin under contract to the Department of Energy. This unit is currently on an extended operation test at NASA Glenn Research Center to generate performance data and validate the life and reliability predictions for the generator and the Stirling convertors. A special test facility was designed and built for testing the ASRG-EU. Details of the test facility design are discussed. The facility can operate the convertors under AC bus control or with the ASRG-EU controller. It can regulate input thermal power in either a fixed temperature or fixed power mode. An enclosure circulates cooled air around the ASRG-EU to remove heat rejected from the ASRG-EU by convection. A custom monitoring and data acquisition system supports the test. Various safety features, which allow 2417 unattended operation, are discussed.

  4. Advanced All-Gas Chemical Generation of Atomic Iodine for a COIL, and Testing the COIL Operation Including This Method of Atomic Iodine Generation

    National Research Council Canada - National Science Library

    Kodymova, Jarmila; Spalek, Otomar; Jirasek, Vit; Censky, Miroslav

    2004-01-01

    This report results from a contract tasking Academy of Sciences as follows: The Grantee will investigate advanced methods for chemical generation of atomic iodine for a Chemical Oxygen-Iodine Laser (COIL...

  5. Advanced exergoenvironmental assessment of a natural gas-fired electricity generating facility

    International Nuclear Information System (INIS)

    Açıkkalp, Emin; Aras, Haydar; Hepbasli, Arif

    2014-01-01

    Highlights: • Advanced exergoenvironmental analysis was conducted for an electricity generating facility. • Exergy destructions and environmental effects were divided into parts. • Environmental relations between the components were determined. • Environmental improvement strategies of the system were determined. - Abstract: This paper presents conventional and advanced exergoenvironmental analyses of an electricity generation facility located in the Eskisehir Industry Estate Zone, Turkey. This facility consists of gas turbine and steam cycles, which generate electrical power of approximately 37 MW and 18 MW, respectively. Exergy efficiency of the system is 0.402 and exergy destruction rate of the system is 78.242 MW. Unit exergy cost of electrical power generated by the system is 25.66 $/GJ and total exergoeconomic factor of the system is 0.279. Conventional exergy analysis method was applied to the system first. Next, exergy environmental impacts of exergy destruction rate within the facility’s components were divided into four parts generally, as endogenous, exogenous, avoidable and unavoidable environmental impact of exergy destruction rate. Through this analysis, improvement potential of the environmental impacts of the components and the overall system and the environmental relations between the components were then determined. Finally, exergoenvironmental factor was determined as 0.277 and environmental impact of the electricity was 8.472 (Pts/h). The system has 33% development potential for environmental impacts while its components have weak relations because of big endogenous parts of environmental impacts (80%). It may be concluded that advanced exergoenvironmental analysis indicated that priority should be given to the GT and CC, while defining the improvement strategies

  6. Development of a Power Electronics Controller for the Advanced Stirling Radioisotope Generator

    Science.gov (United States)

    Leland, Douglas K.; Priest, Joel F.; Keiter, Douglas E.; Schreiber, Jeffrey G.

    2008-01-01

    Under a U.S. Department of Energy program for radioisotope power systems, Lockheed Martin is developing an Engineering Unit of the Advanced Stirling Radioisotope Generator (ASRG). This is an advanced version of the previously reported SRG110 generator. The ASRG uses Advanced Stirling Convertors (ASCs) developed by Sunpower Incorporated under a NASA Research Announcement contract. The ASRG makes use of a Stirling controller based on power electronics that eliminates the tuning capacitors. The power electronics controller synchronizes dual-opposed convertors and maintains a fixed frequency operating point. The controller is single-fault tolerant and uses high-frequency pulse width modulation to create the sinusoidal currents that are nearly in phase with the piston velocity, eliminating the need for large series tuning capacitors. Sunpower supports this effort through an extension of their controller development intended for other applications. Glenn Research Center (GRC) supports this effort through system dynamic modeling, analysis and test support. The ASRG design arrived at a new baseline based on a system-level trade study and extensive feedback from mission planners on the necessity of single-fault tolerance. This paper presents the baseline design with an emphasis on the power electronics controller detailed design concept that will meet space mission requirements including single fault tolerance.

  7. A pilot study using next-generation sequencing in advanced cancers: feasibility and challenges.

    Science.gov (United States)

    Weiss, Glen J; Liang, Winnie S; Demeure, Michael J; Kiefer, Jeff A; Hostetter, Galen; Izatt, Tyler; Sinari, Shripad; Christoforides, Alexis; Aldrich, Jessica; Kurdoglu, Ahmet; Phillips, Lori; Benson, Hollie; Reiman, Rebecca; Baker, Angela; Marsh, Vickie; Von Hoff, Daniel D; Carpten, John D; Craig, David W

    2013-01-01

    New anticancer agents that target a single cell surface receptor, up-regulated or amplified gene product, or mutated gene, have met with some success in treating advanced cancers. However, patients' tumors still eventually progress on these therapies. If it were possible to identify a larger number of targetable vulnerabilities in an individual's tumor, multiple targets could be exploited with the use of specific therapeutic agents, thus possibly giving the patient viable therapeutic alternatives. In this exploratory study, we used next-generation sequencing technologies (NGS) including whole genome sequencing (WGS), and where feasible, whole transcriptome sequencing (WTS) to identify genomic events and associated expression changes in advanced cancer patients. WGS on paired tumor and normal samples from nine advanced cancer patients and WTS on six of these patients' tumors was completed. One patient's treatment was based on targets and pathways identified by NGS and the patient had a short-lived PET/CT response with a significant reduction in his tumor-related pain. To design treatment plans based on information garnered from NGS, several challenges were encountered: NGS reporting delays, communication of results to out-of-state participants and their treating oncologists, and chain of custody handling for fresh biopsy samples for Clinical Laboratory Improvement Amendments (CLIA) target validation. While the initial effort was a slower process than anticipated due to a variety of issues, we demonstrate the feasibility of using NGS in advanced cancer patients so that treatments for patients with progressing tumors may be improved.

  8. Advancing Pain Education in Canadian Physiotherapy Programmes: Results of a Consensus-Generating Workshop.

    Science.gov (United States)

    Wideman, Timothy H; Miller, Jordan; Bostick, Geoff; Thomas, Aliki; Bussières, André

    2018-01-01

    Purpose: This article reports on a national stakeholder workshop that focused on advancing pain education in physiotherapy programmes across Canada. Methods: Workshop participants included national leaders from the following stakeholder groups: people living with pain; physiotherapy students and recent graduates; pain educators; physiotherapy programme administrators; and representatives from the Canadian Alliance of Physiotherapy Regulators, Physiotherapy Education Accreditation Canada, Canadian Physiotherapy Association, and Physiotherapy Practice Profile project. During the workshop, barriers to, facilitators of, and strategies for advancing pain education were discussed, and a stakeholder-endorsed consensus statement was generated. The workshop was recorded, and data were thematically analyzed. Results: Participants identified important barriers and facilitators associated with the field of pain, standards and regulatory processes, physiotherapy programmes, and physiotherapy students and people living with pain. Strategies for advancing pain education included integrating pain competencies into standards and regulatory policy, encouraging the development of best teaching practices, partnering with people living with pain, building awareness, and setting goals and assessing clear outcomes. The consensus statement highlighted the central importance of pain education for physiotherapists and the need for a reference standard to guide its implementation in the Canadian context. Conclusion: This was the first initiative to specifically explore national stakeholders' perceptions of pain education. The workshop outcomes provide a strong mandate and direction for advancing pain education across Canadian physiotherapy programmes.

  9. External Magnetic Field Reduction Techniques for the Advanced Stirling Radioisotope Generator

    Science.gov (United States)

    Niedra, Janis M.; Geng, Steven M.

    2013-01-01

    Linear alternators coupled to high efficiency Stirling engines are strong candidates for thermal-to-electric power conversion in space. However, the magnetic field emissions, both AC and DC, of these permanent magnet excited alternators can interfere with sensitive instrumentation onboard a spacecraft. Effective methods to mitigate the AC and DC electromagnetic interference (EMI) from solenoidal type linear alternators (like that used in the Advanced Stirling Convertor) have been developed for potential use in the Advanced Stirling Radioisotope Generator. The methods developed avoid the complexity and extra mass inherent in data extraction from multiple sensors or the use of shielding. This paper discusses these methods, and also provides experimental data obtained during breadboard testing of both AC and DC external magnetic field devices.

  10. Challenges and solutions for adoption of advanced cycles for power generation in today's business climate

    International Nuclear Information System (INIS)

    Brockway, D.

    2002-01-01

    plant in Victoria and South Australia. In order to minimise the impact of new coal fired power generation on the environment, advanced cycle power generation systems must be developed and demonstrated to be commercially viable in the current business climate. The potential greenhouse gas abatement expected from advanced cycles for power generation is illustrated in Figure 1 for high moisture brown coal. While there remains a considerable amount of R and D to be completed on the development of advanced cycles, the principal challenge for the implementation of these technologies in the future is a consequence of the manner in which the power generation industry has developed worldwide over the last decade or so. That is, the technical knowledge for the implementation of these technologies is available or will be in the next few years. The principal challenge is not research and development of the technologies but rather creation of a business climate where the risk and cost hurdles to their introduction can be overcome

  11. Study of high-performance non-equilibrium MHD generator for compact fusion advanced Rankine cycle

    Energy Technology Data Exchange (ETDEWEB)

    Inui, Yoshitaka; Miki, Nobufumi; Ishikawa, Motoo; Umoto, Juro (Dept. of Electrical Engineering, Kyoto Univ. (Japan)); Yoshikawa, Kiyoshi (Inst. of Atomic Energy, Kyoto Univ. (Japan))

    1991-12-01

    The conceptual design of high-performance non-equilibrium disk magnetohydrodynamic (MHD) generator for compact fusion advanced Rankine (CFAR) cycle has already been performed by the authors. In the design, however, the inlet stagnation pressure may be too high (12.8 atm), making it difficult to design the other components of the cycle. The present study, therefore, performs conceptual design of high performance MHD generator with low stagnation pressure (4 atm) for CFAR cycle. For this purpose, the distribution of magnetic flux density is dealt as unknown variable and is calculated from given inlet conditions, generator configuration and electron temperature. The calculations are performed by using quasi-one-dimensional steady-state simulation code. All conditions except the load current and seed fraction are, at first, determined by preliminary study of design conditions. Then, calculations are performed for various load currents and seed fractions to find out the generator with highest enthalpy extraction ratio. The enthalpy extraction ratio of conceptually designed generator reaches 54.5%. (orig.).

  12. The Advanced Light Source: A third-generation Synchrotron Radiation Source

    Energy Technology Data Exchange (ETDEWEB)

    Robinson, Arthur L.

    2002-08-14

    The Advanced Light Source (ALS) at the E.O. Lawrence Berkeley National Laboratory (Berkeley Lab) of the University of California is a ''third-generation'' synchrotron radiation source optimized for highest brightness at ultraviolet and soft x-ray photon energies. It also provides world-class performance at hard x-ray photon energies. Berkeley Lab operates the ALS for the United States Department of Energy as a national user facility that is available 24 hours/day around the year for research by scientists from industrial, academic, and government laboratories primarily from the United States but also from abroad.

  13. Advanced glycation end products delay corneal epithelial wound healing through reactive oxygen species generation.

    Science.gov (United States)

    Shi, Long; Chen, Hongmei; Yu, Xiaoming; Wu, Xinyi

    2013-11-01

    Delayed healing of corneal epithelial wounds is a serious complication in diabetes. Advanced glycation end products (AGEs) are intimately associated with the diabetic complications and are deleterious to the wound healing process. However, the effect of AGEs on corneal epithelial wound healing has not yet been evaluated. In the present study, we investigated the effect of AGE-modified bovine serum albumin (BSA) on corneal epithelial wound healing and its underlying mechanisms. Our data showed that AGE-BSA significantly increased the generation of intracellular ROS in telomerase-immortalized human corneal epithelial cells. However, the generation of intracellular ROS was completely inhibited by antioxidant N-acetylcysteine (NAC), anti-receptor of AGEs (RAGE) antibodies, or the inhibitor of NADPH oxidase. Moreover, AGE-BSA increased NADPH oxidase activity and protein expression of NADPH oxidase subunits, p22phox and Nox4, but anti-RAGE antibodies eliminated these effects. Furthermore, prevention of intracellular ROS generation using NAC or anti-RAGE antibodies rescued AGE-BSA-delayed epithelial wound healing in porcine corneal organ culture. In conclusion, our results demonstrated that AGE-BSA impaired corneal epithelial wound healing ex vivo. AGE-BSA increased intracellular ROS generation through NADPH oxidase activation, which accounted for the delayed corneal epithelial wound healing. These results may provide better insights for understanding the mechanism of delayed healing of corneal epithelial wounds in diabetes.

  14. Advanced fuels with reduced actinide generation. Proceedings of a technical committee meeting

    International Nuclear Information System (INIS)

    1996-11-01

    Nuclear energy can play an important future role in supplying the world population with energy. However, this form of energy will be successful only under certain conditions: it must meet very strict safety requirements, it must be economically competitive, and it must be acceptable to the public. Nuclear power produces radioactive wastes and in several countries the public raises concern about safety. Much development work on advanced nuclear power systems is going on in several countries, with participation of both governmental and private industries to meet these conditions. In the framework of this IAEA activity the Technical Committee Meeting on Advanced Fuels with Reduced Actinide Generation was organized. The aim of the meeting was to highlight current research activities and to identify new research areas and fields of possible co-operation. The scope of the meeting included advanced fuels for all types of nuclear reactors: light water reactors, heavy water reactors, high temperature reactors, fast reactors, molten salt reactors and for accelerator driven systems. Other topics covered a wide range of investigations made, or to be made in the Member States. Refs, figs, tabs

  15. The Next Generation Nuclear Plant/Advanced Gas Reactor Fuel Irradiation Experiments in the Advanced Test Reactor

    International Nuclear Information System (INIS)

    Grover, S. Blaine

    2009-01-01

    The United States Department of Energy's Next Generation Nuclear Plant (NGNP) Program will be irradiating eight separate low enriched uranium (LEU) tri-isotopic (TRISO) particle fuel (in compact form) experiments in the Advanced Test Reactor (ATR) located at the Idaho National Laboratory (INL). The ATR has a long history of irradiation testing in support of reactor development and the INL has been designated as the new United States Department of Energy's lead laboratory for nuclear energy development. The ATR is one of the world's premiere test reactors for performing long term, high flux, and/or large volume irradiation test programs. These irradiations and fuel development are being accomplished to support development of the next generation reactors in the United States, and will be irradiated over the next ten years to demonstrate and qualify new particle fuel for use in high temperature gas reactors. The goals of the irradiation experiments are to provide irradiation performance data to support fuel process development, to qualify fuel for normal operating conditions, to support development and validation of fuel performance and fission product transport models and codes, and to provide irradiated fuel and materials for post irradiation examination (PIE) and safety testing. The experiments, which will each consist of at least six separate capsules, will be irradiated in an inert sweep gas atmosphere with individual on-line temperature monitoring and control of each capsule. The sweep gas will also have on-line fission product monitoring on its effluent to track performance of the fuel in each individual capsule during irradiation. The first experiment (designated AGR-1) started irradiation in December 2006, and the second experiment (AGR-2) is currently in the design phase. The design of test trains, as well as the support systems and fission product monitoring system that will monitor and control the experiment during irradiation will be discussed. In

  16. Advanced control of direct-driven PMSG generator in wind turbine system

    Directory of Open Access Journals (Sweden)

    Gajewski Piotr

    2016-12-01

    Full Text Available The paper presents the advanced control system of the wind energy conversion with a variable speed wind turbine. The considered system consists of a wind turbine with the permanent magnet synchronous generator (PMSG, machine side converter (MSC, grid side converter (GSC and control circuits. The mathematical models of a wind turbine system, the PMSG generator and converters have been described. The control algorithms of the converter systems based on the methods of vector control have been applied. In the advanced control system of the machine side converter the optimal MPPT control method has been used. Additionally the pitch control scheme is included in order to achieve the limitation of maximum power and to prevent mechanical damage of the wind turbine. In the control system of the grid side converter the control of active and reactive power has been applied with the application of Voltage Oriented Control (VOC. The performance of the considered wind energy system has been studied by digital simulation. The results of simulation studies confirmed the good effectiveness of the considered wind turbine system and very good performance of the proposed methods of vector control and control systems.

  17. Review article: next-generation transformative advances in the pathogenesis and management of autoimmune hepatitis.

    Science.gov (United States)

    Czaja, A J

    2017-11-01

    Advances in autoimmune hepatitis that transform current concepts of pathogenesis and management can be anticipated as products of ongoing investigations driven by unmet clinical needs and an evolving biotechnology. To describe the advances that are likely to become transformative in autoimmune hepatitis, based on the direction of current investigations. Pertinent abstracts were identified in PubMed by multiple search terms. Full-length articles were selected for review, and a secondary bibliography was developed. The discovery process was repeated, and a tertiary bibliography was identified. The number of abstracts reviewed was 2830, and the number of full-length articles reviewed exceeded 150. Risk-laden allelic variants outside the major histocompatibility complex (rs3184504, r36000782) are being identified by genome-wide association studies, and their gene products are potential therapeutic targets. Epigenetic changes associated with environmental cues can enhance the transcriptional activity of genes, and chromatin re-structuring and antagonists of noncoding molecules of ribonucleic acid are feasible interventions. The intestinal microbiome is a discovery field for microbial products and activated immune cells that may translocate to the periphery and respond to manipulation. Epidemiological studies and controlled interview-based surveys may implicate environmental and xenobiotic factors that warrant evidence-based changes in lifestyle, and site-directed molecular and cellular interventions promise to change the paradigm of treatment from one of blanket immunosuppression. Advances in genetics, epigenetics, pathophysiology, epidemiology, and site-directed molecular and cellular interventions constitute the next generation of transformative advances in autoimmune hepatitis. © 2017 John Wiley & Sons Ltd.

  18. A pilot study using next-generation sequencing in advanced cancers: feasibility and challenges.

    Directory of Open Access Journals (Sweden)

    Glen J Weiss

    Full Text Available New anticancer agents that target a single cell surface receptor, up-regulated or amplified gene product, or mutated gene, have met with some success in treating advanced cancers. However, patients' tumors still eventually progress on these therapies. If it were possible to identify a larger number of targetable vulnerabilities in an individual's tumor, multiple targets could be exploited with the use of specific therapeutic agents, thus possibly giving the patient viable therapeutic alternatives.In this exploratory study, we used next-generation sequencing technologies (NGS including whole genome sequencing (WGS, and where feasible, whole transcriptome sequencing (WTS to identify genomic events and associated expression changes in advanced cancer patients.WGS on paired tumor and normal samples from nine advanced cancer patients and WTS on six of these patients' tumors was completed. One patient's treatment was based on targets and pathways identified by NGS and the patient had a short-lived PET/CT response with a significant reduction in his tumor-related pain. To design treatment plans based on information garnered from NGS, several challenges were encountered: NGS reporting delays, communication of results to out-of-state participants and their treating oncologists, and chain of custody handling for fresh biopsy samples for Clinical Laboratory Improvement Amendments (CLIA target validation.While the initial effort was a slower process than anticipated due to a variety of issues, we demonstrate the feasibility of using NGS in advanced cancer patients so that treatments for patients with progressing tumors may be improved.

  19. Advanced Soldier Thermoelectric Power System for Power Generation from Battlefield Heat Sources

    Energy Technology Data Exchange (ETDEWEB)

    Hendricks, Terry J.; Hogan, Tim; Case, Eldon D.; Cauchy, Charles J.

    2010-09-01

    The U.S. military uses large amounts of fuel during deployments and battlefield operations. This project sought to develop a lightweight, small form-factor, soldier-portable advanced thermoelectric (TE) system prototype to recover and convert waste heat from various deployed military equipment (i.e., diesel generators/engines, incinerators, vehicles, and potentially mobile kitchens), with the ultimate purpose of producing power for soldier battery charging, advanced capacitor charging, and other battlefield power applications. The technical approach employed microchannel technology, a unique “power panel” approach to heat exchange/TE system integration, and newly-characterized LAST (lead-antimony-silver-telluride) and LASTT (lead-antimony-silver-tin-telluride) TE materials segmented with bismuth telluride TE materials in designing a segmented-element TE power module and system. This project researched never-before-addressed system integration challenges (thermal expansion, thermal diffusion, electrical interconnection, thermal and electrical interfaces) of designing thin “power panels” consisting of alternating layers of thin, microchannel heat exchangers (hot and cold) sandwiching thin, segmented-element TE power generators. The TE properties, structurally properties, and thermal fatigue behavior of LAST and LASTT materials were developed and characterized such that the first segmented-element TE modules using LAST / LASTT materials were fabricated and tested at hot-side temperatures = 400 °C and cold-side temperatures = 40 °C. LAST / LASTT materials were successfully segmented with bismuth telluride and electrically interconnected with diffusion barrier materials and copper strapping within the module electrical circuit. A TE system design was developed to produce 1.5-1.6 kW of electrical energy using these new TE modules from the exhaust waste heat of 60-kW Tactical Quiet Generators as demonstration vehicles.

  20. Recent advances on developing 3rd generation enzyme electrode for biosensor applications.

    Science.gov (United States)

    Das, Priyanki; Das, Madhuri; Chinnadayyala, Somasekhar R; Singha, Irom Manoj; Goswami, Pranab

    2016-05-15

    The electrochemical biosensor with enzyme as biorecognition element is traditionally pursued as an attractive research topic owing to their high commercial perspective in healthcare and environmental sectors. The research interest on the subject is sharply increased since the beginning of 21st century primarily, due to the concomitant increase in knowledge in the field of material science. The remarkable effects of many advance materials such as, conductive polymers and nanomaterials, were acknowledged in the developing efficient 3rd generation enzyme bioelectrodes which offer superior selectivity, sensitivity, reagent less detection, and label free fabrication of biosensors. The present review article compiles the major knowledge surfaced on the subject since its inception incorporating the key review and experimental papers published during the last decade which extensively cover the development on the redox enzyme based 3rd generation electrochemical biosensors. The tenet involved in the function of these direct electrochemistry based enzyme electrodes, their characterizations and various strategies reported so far for their development such as, nanofabrication, polymer based and reconstitution approaches are elucidated. In addition, the possible challenges and the future prospects in the development of efficient biosensors following this direct electrochemistry based principle are discussed. A comparative account on the design strategies and critical performance factors involved in the 3rd generation biosensors among some selected prominent works published on the subject during last decade have also been included in a tabular form for ready reference to the readers. Copyright © 2015 Elsevier B.V. All rights reserved.

  1. Advanced Stirling Radioisotope Generator Engineering Unit 2 (ASRG EU2) Final Assembly

    Science.gov (United States)

    Oriti, Salvatore M.

    2015-01-01

    NASA Glenn Research Center (GRC) has recently completed the assembly of a unique Stirling generator test article for laboratory experimentation. Under the Advanced Stirling Radioisotope Generator (ASRG) flight development contract, NASA GRC initiated a task to design and fabricate a flight-like generator for in-house testing. This test article was given the name ASRG Engineering Unit 2 (EU2) as it was effectively the second engineering unit to be built within the ASRG project. The intent of the test article was to duplicate Lockheed Martin's qualification unit ASRG design as much as possible to enable system-level tests not previously possible at GRC. After the cancellation of the ASRG flight development project, the decision was made to continue the EU2 build, and make use of a portion of the hardware from the flight development project. GRC and Lockheed Martin engineers collaborated to develop assembly procedures, leveraging the valuable knowledge gathered by Lockheed Martin during the ASRG development contract. The ASRG EU2 was then assembled per these procedures at GRC with Lockheed Martin engineers on site. The assembly was completed in August 2014. This paper details the components that were used for the assembly, and the assembly process itself.

  2. Study of heat transfer through a cavity receiver for a solar powered advanced Stirling engine generator

    International Nuclear Information System (INIS)

    Hussain, T.; Islam, M.D.; Kubo, I.; Watanabe, T.

    2016-01-01

    Stirling engine operated by concentrated solar energy can be a great mean to generate power. Highly concentrated solar radiations with minimum heat loss from cavity receiver are required to operate the Stirling engine. Therefore, heat transfer study of the cavity receiver is required for the maximum utilization of solar energy with minimum heat losses for the efficient Stirling engine generator. In this study, experiments were performed to find the most suitable cavity receiver configuration for maximum solar radiation utilizations by an Advanced Stirling Engine Generator (ADSEG). Dimensionless parameter: aperture ration (AR = d/D) and aperture position (AP = H/D) were used to characterize the different configurations of cylindrical cavity receiver. Experimental heat loss analysis (Convection, radiation and total heat loss) as well as air film temperature profiles along the wall height (H) of the receiver for different configurations of the cavity receiver was performed in this experiment for its selection. Based on experimental results, among the four different configurations of cylindrical cavity receiver, Type IV (AR = 0.5 AP = 0.53) was found to be the most suitable receiver for the ADSEG system.

  3. Segregation Behaviour of Third Generation Advanced High-Strength Mn-Al Steels

    Directory of Open Access Journals (Sweden)

    A. Grajcar

    2012-04-01

    Full Text Available The paper addresses the macro- and microsegregation of alloying elements in the new-developed Mn-Al TRIP steels, which belong to the third generation of advanced high-strength steels (AHSS used in the automotive industry. The segregation behaviour both in the as-cast state and after hot forging was assessed in the macro scale by OES and by EDS measurements in different structural constituents. The structural investigations were carried out using light and scanning electron microscopy. A special attention was paid to the effect of Nb microaddition on the structure and the segregation of alloying elements. The tendency of Mn and Al to macrosegregation was found. It is difficult to remove in Nb-free steels. Microsegregation of Mn and Al between austenite and ferritic structural constituents can be removed.

  4. Advanced Stirling Radioisotope Generator Thermal Power Model in Thermal Desktop SINDA/FLUINT Analyzer

    Science.gov (United States)

    Wang, Xiao-Yen; Fabanich, William A.; Schmitz, Paul C.

    2012-01-01

    This paper presents a three-dimensional Advanced Stirling Radioisotope Generator (ASRG) thermal power model that was built using the Thermal Desktop SINDA/FLUINT thermal analyzer. The model was correlated with ASRG engineering unit (EU) test data and ASRG flight unit predictions from Lockheed Martin's Ideas TMG thermal model. ASRG performance under (1) ASC hot-end temperatures, (2) ambient temperatures, and (3) years of mission for the general purpose heat source fuel decay was predicted using this model for the flight unit. The results were compared with those reported by Lockheed Martin and showed good agreement. In addition, the model was used to study the performance of the ASRG flight unit for operations on the ground and on the surface of Titan, and the concept of using gold film to reduce thermal loss through insulation was investigated.

  5. Battery-free Wireless Sensor Network For Advanced Fossil-Fuel Based Power Generation

    Energy Technology Data Exchange (ETDEWEB)

    Yi Jia

    2011-02-28

    This report summarizes technical progress achieved during the project supported by the Department of Energy under Award Number DE-FG26-07NT4306. The aim of the project was to conduct basic research into battery-free wireless sensing mechanism in order to develop novel wireless sensors and sensor network for physical and chemical parameter monitoring in a harsh environment. Passive wireless sensing platform and five wireless sensors including temperature sensor, pressure sensor, humidity sensor, crack sensor and networked sensors developed and demonstrated in our laboratory setup have achieved the objective for the monitoring of various physical and chemical parameters in a harsh environment through remote power and wireless sensor communication, which is critical to intelligent control of advanced power generation system. This report is organized by the sensors developed as detailed in each progress report.

  6. Stochastic Modeling of Rainfall Series in Kelantan Using an Advanced Weather Generator

    Directory of Open Access Journals (Sweden)

    A. H. Syafrina

    2018-02-01

    Full Text Available Weather generator is a numerical tool that uses existing meteorological records to generate series of synthetic weather data. The AWE-GEN (Advanced Weather Generator model has been successful in producing a broad range of temporal scale weather variables, ranging from the high-frequency hourly values to the low-frequency inter-annual variability. In Malaysia, AWE-GEN has produced reliable projections of extreme rainfall events for some parts of Peninsular Malaysia. This study focuses on the use of AWE-GEN model to assess rainfall distribution in Kelantan. Kelantan is situated on the north east of the Peninsular, a region which is highly susceptible to flood. Embedded within the AWE-GEN model is the Neyman Scott process which employs parameters to represent physical rainfall characteristics. The use of correct probability distributions to represent the parameters is imperative to allow reliable results to be produced. This study compares the performance of two probability distributions, Weibull and Gamma to represent rainfall intensity and the better distribution found was used subsequently to simulate hourly scaled rainfall series. Thirty years of hourly scaled meteorological data from two stations in Kelantan were used in model construction. Results indicate that both probability distributions are capable of replicating the rainfall series at both stations very well, however numerical evaluations suggested that Gamma performs better. Despite Gamma not being a heavy tailed distribution, it is able to replicate the key characteristics of rainfall series and particularly extreme values. The overall simulation results showed that the AWE-GEN model is capable of generating tropical rainfall series which could be beneficial in flood preparedness studies in areas vulnerable to flood.

  7. On the Way towards Fourth-Generation Mobile: 3GPP LTE and LTE-Advanced

    Directory of Open Access Journals (Sweden)

    Martín-Sacristán David

    2009-01-01

    Full Text Available Abstract Long-Term Evolution (LTE is the new standard recently specified by the 3GPP on the way towards fourth-generation mobile. This paper presents the main technical features of this standard as well as its performance in terms of peak bit rate and average cell throughput, among others. LTE entails a big technological improvement as compared with the previous 3G standard. However, this paper also demonstrates that LTE performance does not fulfil the technical requirements established by ITU-R to classify one radio access technology as a member of the IMT-Advanced family of standards. Thus, this paper describes the procedure followed by the 3GPP to address these challenging requirements. Through the design and optimization of new radio access techniques and a further evolution of the system, the 3GPP is laying down the foundations of the future LTE-Advanced standard, the 3GPP candidate for 4G. This paper offers a brief insight into these technological trends.

  8. On the Way towards Fourth-Generation Mobile: 3GPP LTE and LTE-Advanced

    Directory of Open Access Journals (Sweden)

    David Martín-Sacristán

    2009-01-01

    Full Text Available Long-Term Evolution (LTE is the new standard recently specified by the 3GPP on the way towards fourth-generation mobile. This paper presents the main technical features of this standard as well as its performance in terms of peak bit rate and average cell throughput, among others. LTE entails a big technological improvement as compared with the previous 3G standard. However, this paper also demonstrates that LTE performance does not fulfil the technical requirements established by ITU-R to classify one radio access technology as a member of the IMT-Advanced family of standards. Thus, this paper describes the procedure followed by the 3GPP to address these challenging requirements. Through the design and optimization of new radio access techniques and a further evolution of the system, the 3GPP is laying down the foundations of the future LTE-Advanced standard, the 3GPP candidate for 4G. This paper offers a brief insight into these technological trends.

  9. New generation of cryogen free advanced superconducting magnets for neutron scattering experiments

    International Nuclear Information System (INIS)

    Kirichek, O; Adroja, D T; Manuel, P; Bewley, R I; Brown, J; Kouzmenko, G; Wotherspoon, R

    2012-01-01

    Recent advances in superconducting technology and cryocooler refrigeration have resulted in a new generation of advanced superconducting magnets for neutron beam applications. These magnets have outstanding parameters such as high homogeneity and stability at highest magnetic fields possible, a reasonably small stray field, low neutron scattering background and larger exposure to neutron detectors. At the same time the pulse tube refrigeration technology provides a complete re-condensing regime which allows to minimise the requirements for cryogens without introducing additional noise and mechanical vibrations. The magnets can be used with dilution refrigerator insert which expands the temperature range from 20mK to 300K. Here we are going to present design, test results and the operational data of the 14T magnet for neutron diffraction and the 9T wide angle chopper magnet for neutron spectroscopy developed by Oxford Instruments in collaboration with ISIS neutron source. First scientific results obtained from the neutron scattering experiments with these magnets are also going to be discussed.

  10. NASA Glenn Research Center Support of the Advanced Stirling Radioisotope Generator Project

    Science.gov (United States)

    Wilson, Scott D.; Wong, Wayne A.

    2015-01-01

    A high-efficiency radioisotope power system was being developed for long-duration NASA space science missions. The U.S. Department of Energy (DOE) managed a flight contract with Lockheed Martin Space Systems Company to build Advanced Stirling Radioisotope Generators (ASRGs), with support from NASA Glenn Research Center. DOE initiated termination of that contract in late 2013, primarily due to budget constraints. Sunpower, Inc., held two parallel contracts to produce Advanced Stirling Convertors (ASCs), one with Lockheed Martin to produce ASC-F flight units, and one with Glenn for the production of ASC-E3 engineering unit "pathfinders" that are built to the flight design. In support of those contracts, Glenn provided testing, materials expertise, Government-furnished equipment, inspection capabilities, and related data products to Lockheed Martin and Sunpower. The technical support included material evaluations, component tests, convertor characterization, and technology transfer. Material evaluations and component tests were performed on various ASC components in order to assess potential life-limiting mechanisms and provide data for reliability models. Convertor level tests were conducted to characterize performance under operating conditions that are representative of various mission conditions. Despite termination of the ASRG flight development contract, NASA continues to recognize the importance of high-efficiency ASC power conversion for Radioisotope Power Systems (RPS) and continues investment in the technology, including the continuation of the ASC-E3 contract. This paper describes key Government support for the ASRG project and future tests to be used to provide data for ongoing reliability assessments.

  11. Bioenhanced advanced third generation solid dispersion of tadalafil: Repurposing with improved therapy in pyelonephritis

    Directory of Open Access Journals (Sweden)

    Prashant P. Mande

    2017-11-01

    Full Text Available Tadalafil (TDL a BCS-II drug is recently reported for repurposing nephroprotective effect in Pyelonephritis (PN. However, poor water solubility and dissolution rate limited oral bioavailability pose serious challenges in its therapeutic applications. We present an advanced third generation Solid Dispersion (SD of TDL comprising a polymer in combination with a Self Micro-emulsifying Composition (SMEC to achieve high drug loading, improved stability and rapid dissolution of TDL for enhancing bioavailability and efficacy in PN. TDL-SMEC-SD was coated onto rapidly disintegrating inert tablet cores which disintegrated rapidly in water to release SD as a film. TDL-SMEC-SD was evaluated for in-vivo oral bioavailability and in-vivo efficacy in lipopolysaccharide-induced PN in rats. TDL exhibited high solubility (45.6 mg/ml in the SMEC. TDL-SMEC-SD exhibited remarkably high TDL loading (45%w/w, exceptionally low contact angle (9°, rapid in-vitro release (t50 7.3 min, microemulsion formation (globule size ~100 nm in aqueous dispersion, and stability as per ICH guidelines. SEM, DSC, and XRD confirmed high physical stability. A relative bioavailability of 350% and 150% compared to TDL and TDL-SD without SMEC respectively, established the superiority of TDL-SMEC-SD. A significant reduction in serum creatinine, blood urea nitrogen and nitric oxide levels in the lipopolysaccharide-induced PN confirmed the benefit of the TDL-SMEC-SD. The advanced third generation SMEC SDs presents the possibility of platform technology for bioenhancement of poorly water soluble drugs.

  12. An Advanced Bayesian Method for Short-Term Probabilistic Forecasting of the Generation of Wind Power

    Directory of Open Access Journals (Sweden)

    Antonio Bracale

    2015-09-01

    Full Text Available Currently, among renewable distributed generation systems, wind generators are receiving a great deal of interest due to the great economic, technological, and environmental incentives they involve. However, the uncertainties due to the intermittent nature of wind energy make it difficult to operate electrical power systems optimally and make decisions that satisfy the needs of all the stakeholders of the electricity energy market. Thus, there is increasing interest determining how to forecast wind power production accurately. Most the methods that have been published in the relevant literature provided deterministic forecasts even though great interest has been focused recently on probabilistic forecast methods. In this paper, an advanced probabilistic method is proposed for short-term forecasting of wind power production. A mixture of two Weibull distributions was used as a probability function to model the uncertainties associated with wind speed. Then, a Bayesian inference approach with a particularly-effective, autoregressive, integrated, moving-average model was used to determine the parameters of the mixture Weibull distribution. Numerical applications also are presented to provide evidence of the forecasting performance of the Bayesian-based approach.

  13. Advanced marine reactor MRX and its application for electricity and heat co-generation

    International Nuclear Information System (INIS)

    Ishida, T.; Ochiai, M.; Hoshi, T.

    2000-01-01

    The basic concept of an innovative advanced marine reactor MRX has been established by design study toward the goals of light-weightiness, compactness, and safety and reliability improvement with adoption of several new technologies. The MRX is the integral-type PWR aimed for use of ship propulsion. Adoption of a water-filled containment makes the reactor light-weighted and compact greatly. The total weight and volume of the reactor are 1600 tons and 1210 m 3 , which are equivalent to halves of the Mutsu, although the reactor power of MRX is three times greater. An engineered safety system of the MRX is a simplified passive system, function of which is confirmed by the safety analysis to be able to keep the reactor integrity even in a case of accident. Reliability of the system is evaluated by the PSA and revealed to have two orders smaller core damage occurrence frequency than existing PWRs. The MRX can be applied to an energy supply system of electricity and heat co-generation. Concept of the nuclear energy supply system is designed to generate electricity, heat and fresh water. The nuclear barge is shown to be a possible nuclear energy supply system with advantage of being easily moveable. (author)

  14. The Development of the Advanced Light Water Reactor in Korea - The Korean Next Generation Reactor -

    Energy Technology Data Exchange (ETDEWEB)

    Kim, H.G.; Park, Y.S.; Kim, B.S.; Cho, S.J. [Korea Electric Power Research Institute, Taejon (Korea)

    1999-07-01

    Korean next generation reactor (KNGR), which is to be designed as a standard evolutionary advanced light water reactor (ALWR) in Korea, has been developed from 1992 as one of long-term government projects. The major characteristics of the KNGR are as follows; KNGR is 2-loop PWR and its design lift time is 60 years. The CDF and the CFF will be much lower than 10{sup -5}/RY and 10{sup -6}/RY, respectively. For the design improvement, KNGR adopted inconel-690 as a steam generator tube material, four train ECCS, refueling water storage tank inside containment, and double cylindrical concrete containment. For more reliable and easier control, compact workstations have been adopted in the design of main control complex and digital I and C technology is used for protection, control, and monitoring. In addition, KNGR has some passive design features such as fluidic device in safety injection tank, passive secondary condensing system, and passive auto-catalytic hydrogen recombiner to enhance safety. (author). 4 refs., 4 figs.

  15. A hybrid approach for generating ultra-short bunches for advanced accelerator applications

    Energy Technology Data Exchange (ETDEWEB)

    Stratakis, Diktys [Brookhaven National Lab. (BNL), Upton, NY (United States)

    2015-09-01

    Generation of electron beams with high phase-space density, short bunch length and high peak current is an essential requirement for future linear colliders and bright electron beam sources. Unfortunately, such bunches cannot be produced directly from the source since forces from the mutual repulsion of electrons would destroy the brilliance of the beam within a short distance. Here, we detail a beam dynamics study of an innovative two-stage compression scheme that can generate ultra-short bunches without degrading the beam quality. In the first stage, the beam is compressed with an advanced velocity bunching technique in which the longitudinal phase space is rotated so that electrons on the bunch tail become faster than electrons in the bunch head. In the second stage, the beam is further compressed with a conventional magnetic chicane. With the aid of numerical simulations we show that our two-staged scheme is capable to increase the current of a 50 pC bunch to a notable factor of 100 while the emittance growth can be suppressed to 1% with appropriate tailoring of the initial beam distribution.

  16. Next Generation Climate Change Experiments Needed to Advance Knowledge and for Assessment of CMIP6

    Energy Technology Data Exchange (ETDEWEB)

    Katzenberger, John [Aspen Global Change Inst., Basalt, CO (United States); Arnott, James [Aspen Global Change Inst., Basalt, CO (United States); Wright, Alyson [Aspen Global Change Inst., Basalt, CO (United States)

    2014-10-30

    The Aspen Global Change Institute hosted a technical science workshop entitled, “Next generation climate change experiments needed to advance knowledge and for assessment of CMIP6,” on August 4-9, 2013 in Aspen, CO. Jerry Meehl (NCAR), Richard Moss (PNNL), and Karl Taylor (LLNL) served as co-chairs for the workshop which included the participation of 32 scientists representing most of the major climate modeling centers for a total of 160 participant days. In August 2013, AGCI gathered a high level meeting of representatives from major climate modeling centers around the world to assess achievements and lessons learned from the most recent generation of coordinated modeling experiments known as the Coupled Model Intercomparison Project – 5 (CMIP5) as well as to scope out the science questions and coordination structure desired for the next anticipated phase of modeling experiments called CMIP6. The workshop allowed for reflection on the coordination of the CMIP5 process as well as intercomparison of model results, such as were assessed in the most recent IPCC 5th Assessment Report, Working Group 1. For example, this slide from Masahiro Watanabe examines performance on a range of models capturing Atlantic Meridional Overturning Circulation (AMOC).

  17. Advanced airborne 3D computer image generation systems technologies for the year 2000

    Science.gov (United States)

    Bridges, Alan L.

    1992-07-01

    An airborne 3-D computer image generation system (CIGS) is a modular avionics box that receives commands from and sends status information to other avionics units. The CIGS maintains a large amount of data in secondary storage systems and simultaneously drives several display units. Emerging requirements for CIGS include: advanced avionics system architecture requirements and BIT/fault tolerance; real-time operating systems and graphic interface languages in Ada; and geometric/pixel processing functions, rendering system, and frame buffers/display controllers for pictorial displays. In addition, podded sensors (FLIR, LLTV, radar, etc.) will require multiplexing of high-resolution sensor video with graphics overlays. A combination of head-down AMLCD flat panels, helmet-mounted display (HMD), and Head-Up Display (HUD) will require highly parallel graphics generation technology. Generation of high-resolution, real-time 2-D/3-D displays with anti-aliasing, transparency, shading, and motion, however, emphasizes compute-intensive processing. High-performance graphics engines, powerful floating point processors, and parallel architectures are needed to increase the rendering speed, functionality and reliability, while reducing power, space requirements, and cost. The CIGS of the future will feature special high speed busses geared toward real-time graphics processing. The CIG system will be multi-channel, will have a high addressable resolution to drive HUD, 3-D displays in 4-pi-steradian virtual space, and 3-D panoramic displays; and will include fiber optics video distribution between CIG and display units. The head-down display (HDD) is by far the most complex display in that both background and overlay display elements are required. The background is usually generated from terrain/cultural features data. Terrain data is used to generate 2-D map backgrounds or 3-D perspective views duplicating or substituting for the pilot's out-the-window view. Performance of 150

  18. Advanced in-vessel retention design for next generation risk management

    Energy Technology Data Exchange (ETDEWEB)

    Suh, Kune Y.; Hwang, Il Soon [Seoul National University, Seoul (Korea, Republic of)

    1997-12-31

    In the TMI-2 accident, approximately twenty (20) tons of molten core material drained into the lower plenum. Early advanced light water reactor (LWR) designs assumed a lower head failure and incorporated various measures for ex-vessel accident mitigation. However,one of the major findings from the TMI-2 Vessel Investigation Project was that one part of the reactor lower head wall estimated to have attained a temperature of 1100 deg C for about 30 minutes has seemingly experienced a comparatively rapid cooldown with no major threat to the vessel integrity. In this regard, recent empirical and analytical studies have shifted interests to such in-vessel retention designs or strategies as reactor cavity flooding, in-vessel flooding and engineered gap cooling of the vessel. Accurate thermohydrodynamic and creep deformation modeling and rupture prediction are the key to the success in developing practically useful in-vessel accident/risk management strategies. As an advanced in-vessel design concept, this work presents the COrium Attack Syndrome Immunization Structures (COASIS) that are being developed as prospective in-vessel retention devices for a next-generation LWR in concert with existing ex-vessel management measures. Both the engineered gap structures in-vessel (COASISI) and ex-vessel (COASISO) are demonstrated to maintain effective heat transfer geometry during molten core debris attack when applied to the Korean Standard Nuclear Power Plant (KSNPP) reactor. The likelihood of lower head creep rupture during a severe accident is found to be significantly suppressed by the COASIS options. 15 refs., 5 figs., 1 tab. (Author)

  19. Advanced cell culture technology for generation of in vivo-like tissue models

    Directory of Open Access Journals (Sweden)

    Stefan Przyborski

    2017-06-01

    Full Text Available Human tissues are mostly composed of different cell types, that are often highly organised in relation to each other. Often cells are arranged in distinct layers that enable signalling and cell-to-cell interactions. Here we describe the application of scaffold-based technology, that can be used to create advanced organotypic 3D models of various tissue types that more closely resemble in vivo-like conditions (Knight et al., 2011. The scaffold comprises a highly porous polystyrene material, engineered into a 200 micron thick membrane that is presented in various ways including multi-welled plates and well inserts, for use with conventional culture plasticware and medium perfusion systems. This technology has been applied to generate numerous unique types of co-culture model. For example: 1 a full thickness human skin construct comprising dermal fibroblasts and keratinocytes, raised to the air-liquid interface to induce cornification of the upper layers (Fig.1 (Hill et al., 2015; 2 a neuron-glial co-culture to enable the study of neurite outgrowth interacting with astroglial cells to model and investigate the glial scar found in spinal cord injury (Clarke et al., 2016; 3 formation of a sub-mucosa consisting of a polarised simple epithelium, layer of ECM proteins simulating the basement membrane, and underlying stromal tissues (e.g. intestinal mucosa. These organotypic models demonstrate the versatility of scaffold membranes and the creation of advanced in vivo-like tissue models. Creating a layered arrangement more closely simulates the true anatomy and organisation of cells within many tissue types. The addition of different cell types in a temporal and spatial fashion can be used to study inter-cellular relationships and create more physiologically relevant in vivo-like cell-based assays. Methods that are relatively straightforward to use and that recreate the organised structure of real tissues will become valuable research tools for use in

  20. BWR 90 and BWR 90+: Two advanced BWR design generations from ABB

    International Nuclear Information System (INIS)

    Haukeland, S.; Ivung, B.; Pedersen, T.

    1999-01-01

    ABB has two evolutionary advanced light water reactors available today - the BWR 90 boiling water reactor and the System 80+ pressurised water reactor. The BWR 90 is based on the design, construction, commissioning and operation of the BWR 75 plants. The operation experience of the six plants of this advanced design has been very good. The average annual energy availability is above 90%, and total power generation costs have been low. When developing the BWR 90 specific changes were introduced to a reference design, to adapt to technological progress, new safety requirements and to achieve cost savings. The thermal power rating of BWR 90 is 3800 MWth (providing a nominal 1374 MWe net), slightly higher than that of the reference plant ABB Atom has taken advantage of margins gained using a new generation of its SVEA fuel to attain this power rating without major design modifications. The BWR 90 design was completed and offered to the TVO utility in Finland in 1991, as one of the contenders for the fifth Finnish nuclear power plant project. Hence, the design is available today for deployment in new plant projects. Utility views were incorporated through co-operation with the Finnish utility TVO, owner and operator of the two Olkiluoto plants of BWR 75 design. A review against the European Utility Requirement (EUR) set of requirements has been performed, since the design, in 1997, was selected by the EUR Steering Committee to be the first BWR to be evaluated against the EUR documents. The review work was completed in 1998. It will be the subject of an 'EUR Volume 3 Subset for BWR 90' document. ABB is continuing its BWR development work with an 'evolutionary' design called BWR 90+, which aims at developing the BWR as a competitive option for the anticipated revival of the market for new nuclear plants beyond the turn of the century, as well as feeding ideas and inputs to the continuous modernisation efforts at operating plants. The development is performed by ABB Atom

  1. The role of advanced nuclear plants in reducing the environmental and economic impact of greenhouse emissions on electrical generation

    International Nuclear Information System (INIS)

    Redding, J.; Veitch, C.

    1995-01-01

    The paper discusses the potential impact of imposing economic penalties (externalities) in an effort to reduce emission levels and environmental effect of existing and newly constructed electric facilities, on the selection of generation technology and fuel type, and how the nuclear industry's efforts to develop the next generation of nuclear power facilities will provide an economic, low emission generating option to meet the expanding global electrical needs. The efforts of the US nuclear industry to improve the performance and economics of the existing and next generation facilities are presented, focusing on General Electric's Advanced Boiling Water Reactor and Simplified Boiling Water Reactor. 5 refs., 4 figs., 2 tabs

  2. An advanced tube wear and fatigue workstation to predict flow induced vibrations of steam generator tubes

    International Nuclear Information System (INIS)

    Gay, N.; Baratte, C.; Flesch, B.

    1997-01-01

    Flow induced tube vibration damage is a major concern for designers and operators of nuclear power plant steam generators (SG). The operating flow-induced vibrational behaviour has to be estimated accurately to allow a precise evaluation of the new safety margins in order to optimize the maintenance policy. For this purpose, an industrial 'Tube Wear and Fatigue Workstation', called 'GEVIBUS Workstation' and based on an advanced methodology for predictive analysis of flow-induced vibration of tube bundles subject to cross-flow has been developed at Electricite de France. The GEVIBUS Workstation is an interactive processor linking modules as: thermalhydraulic computation, parametric finite element builder, interface between finite element model, thermalhydraulic code and vibratory response computations, refining modelling of fluid-elastic and random forces, linear and non-linear dynamic response and the coupled fluid-structure system, evaluation of tube damage due to fatigue and wear, graphical outputs. Two practical applications are also presented in the paper; the first simulation refers to an experimental set-up consisting of a straight tube bundle subject to water cross-flow, while the second one deals with an industrial configuration which has been observed in some operating steam generators i.e., top tube support plate degradation. In the first case the GEVIBUS predictions in terms of tube displacement time histories and phase planes have been found in very good agreement with experiment. In the second application the GEVIBUS computation showed that a tube with localized degradation is much more stable than a tube located in an extended degradation zone. Important conclusions are also drawn concerning maintenance. (author)

  3. Future projections of extreme precipitation using Advanced Weather Generator (AWE-GEN over Peninsular Malaysia

    Directory of Open Access Journals (Sweden)

    A. H. Syafrina

    2014-09-01

    Full Text Available A stochastic downscaling methodology known as the Advanced Weather Generator, AWE-GEN, has been tested at four stations in Peninsular Malaysia using observations available from 1975 to 2005. The methodology involves a stochastic downscaling procedure based on a Bayesian approach. Climate statistics from a multi-model ensemble of General Circulation Model (GCM outputs were calculated and factors of change were derived to produce the probability distribution functions (PDF. New parameters were obtained to project future climate time series. A multi-model ensemble was used in this study. The projections of extreme precipitation were based on the RCP 6.0 scenario (2081–2100. The model was able to simulate both hourly and 24-h extreme precipitation, as well as wet spell durations quite well for almost all regions. However, the performance of GCM models varies significantly in all regions showing high variability of monthly precipitation for both observed and future periods. The extreme precipitation for both hourly and 24-h seems to increase in future, while extreme of wet spells remain unchanged, up to the return periods of 10–40 years.

  4. Future projections of extreme precipitation using Advanced Weather Generator (AWE-GEN) over Peninsular Malaysia

    Science.gov (United States)

    Syafrina, A. H.; Zalina, M. D.; Juneng, L.

    2014-09-01

    A stochastic downscaling methodology known as the Advanced Weather Generator, AWE-GEN, has been tested at four stations in Peninsular Malaysia using observations available from 1975 to 2005. The methodology involves a stochastic downscaling procedure based on a Bayesian approach. Climate statistics from a multi-model ensemble of General Circulation Model (GCM) outputs were calculated and factors of change were derived to produce the probability distribution functions (PDF). New parameters were obtained to project future climate time series. A multi-model ensemble was used in this study. The projections of extreme precipitation were based on the RCP 6.0 scenario (2081-2100). The model was able to simulate both hourly and 24-h extreme precipitation, as well as wet spell durations quite well for almost all regions. However, the performance of GCM models varies significantly in all regions showing high variability of monthly precipitation for both observed and future periods. The extreme precipitation for both hourly and 24-h seems to increase in future, while extreme of wet spells remain unchanged, up to the return periods of 10-40 years.

  5. System-Level Testing of the Advanced Stirling Radioisotope Generator Engineering Hardware

    Science.gov (United States)

    Chan, Jack; Wiser, Jack; Brown, Greg; Florin, Dominic; Oriti, Salvatore M.

    2014-01-01

    To support future NASA deep space missions, a radioisotope power system utilizing Stirling power conversion technology was under development. This development effort was performed under the joint sponsorship of the Department of Energy and NASA, until its termination at the end of 2013 due to budget constraints. The higher conversion efficiency of the Stirling cycle compared with that of the Radioisotope Thermoelectric Generators (RTGs) used in previous missions (Viking, Pioneer, Voyager, Galileo, Ulysses, Cassini, Pluto New Horizons and Mars Science Laboratory) offers the advantage of a four-fold reduction in Pu-238 fuel, thereby extending its limited domestic supply. As part of closeout activities, system-level testing of flight-like Advanced Stirling Convertors (ASCs) with a flight-like ASC Controller Unit (ACU) was performed in February 2014. This hardware is the most representative of the flight design tested to date. The test fully demonstrates the following ACU and system functionality: system startup; ASC control and operation at nominal and worst-case operating conditions; power rectification; DC output power management throughout nominal and out-of-range host voltage levels; ACU fault management, and system command / telemetry via MIL-STD 1553 bus. This testing shows the viability of such a system for future deep space missions and bolsters confidence in the maturity of the flight design.

  6. A Random-Model Approach to QTL Mapping in Multiparent Advanced Generation Intercross (MAGIC) Populations.

    Science.gov (United States)

    Wei, Julong; Xu, Shizhong

    2016-02-01

    Most standard QTL mapping procedures apply to populations derived from the cross of two parents. QTL detected from such biparental populations are rarely relevant to breeding programs because of the narrow genetic basis: only two alleles are involved per locus. To improve the generality and applicability of mapping results, QTL should be detected using populations initiated from multiple parents, such as the multiparent advanced generation intercross (MAGIC) populations. The greatest challenges of QTL mapping in MAGIC populations come from multiple founder alleles and control of the genetic background information. We developed a random-model methodology by treating the founder effects of each locus as random effects following a normal distribution with a locus-specific variance. We also fit a polygenic effect to the model to control the genetic background. To improve the statistical power for a scanned marker, we release the marker effect absorbed by the polygene back to the model. In contrast to the fixed-model approach, we estimate and test the variance of each locus and scan the entire genome one locus at a time using likelihood-ratio test statistics. Simulation studies showed that this method can increase statistical power and reduce type I error compared with composite interval mapping (CIM) and multiparent whole-genome average interval mapping (MPWGAIM). We demonstrated the method using a public Arabidopsis thaliana MAGIC population and a mouse MAGIC population. Copyright © 2016 by the Genetics Society of America.

  7. Advanced Computational Materials Science: Application to Fusion and Generation IV Fission Reactors (Workshop Report)

    Energy Technology Data Exchange (ETDEWEB)

    Stoller, RE

    2004-07-15

    The ''Workshop on Advanced Computational Materials Science: Application to Fusion and Generation IV Fission Reactors'' was convened to determine the degree to which an increased effort in modeling and simulation could help bridge the gap between the data that is needed to support the implementation of these advanced nuclear technologies and the data that can be obtained in available experimental facilities. The need to develop materials capable of performing in the severe operating environments expected in fusion and fission (Generation IV) reactors represents a significant challenge in materials science. There is a range of potential Gen-IV fission reactor design concepts and each concept has its own unique demands. Improved economic performance is a major goal of the Gen-IV designs. As a result, most designs call for significantly higher operating temperatures than the current generation of LWRs to obtain higher thermal efficiency. In many cases, the desired operating temperatures rule out the use of the structural alloys employed today. The very high operating temperature (up to 1000 C) associated with the NGNP is a prime example of an attractive new system that will require the development of new structural materials. Fusion power plants represent an even greater challenge to structural materials development and application. The operating temperatures, neutron exposure levels and thermo-mechanical stresses are comparable to or greater than those for proposed Gen-IV fission reactors. In addition, the transmutation products created in the structural materials by the high energy neutrons produced in the DT plasma can profoundly influence the microstructural evolution and mechanical behavior of these materials. Although the workshop addressed issues relevant to both Gen-IV and fusion reactor materials, much of the discussion focused on fusion; the same focus is reflected in this report. Most of the physical models and computational methods

  8. Latest developments in advanced network management and cross-sharing of next-generation flux stations

    Science.gov (United States)

    Burba, George; Johnson, Dave; Velgersdyk, Michael; Begashaw, Israel; Allyn, Douglas

    2016-04-01

    In recent years, spatial and temporal flux data coverage improved significantly and on multiple scales, from a single station to continental networks, due to standardization, automation, and management of the data collection, and better handling of the extensive amounts of generated data. However, operating budgets for flux research items, such as labor, travel, and hardware, are becoming more difficult to acquire and sustain. With more stations and networks, larger data flows from each station, and smaller operating budgets, modern tools are required to effectively and efficiently handle the entire process, including sharing data among collaborative groups. On one hand, such tools can maximize time dedicated to publications answering research questions, and minimize time and expenses spent on data acquisition, processing, quality control and overall station management. On the other hand, cross-sharing the stations with external collaborators may help leverage available funding, and promote data analyses and publications. A new low-cost, advanced system, FluxSuite, utilizes a combination of hardware, software and web-services to address these specific demands. It automates key stages of flux workflow, minimizes day-to-day site management, and modernizes the handling of data flows: (i) The system can be easily incorporated into a new flux station, or as un upgrade to many presently operating flux stations, via weatherized remotely-accessible microcomputer, SmartFlux 2, with fully digital inputs (ii) Each next-generation station will measure all parameters needed for flux computations in a digital and PTP time-synchronized mode, accepting digital signals from a number of anemometers and data loggers (iii) The field microcomputer will calculate final fully-processed flux rates in real time, including computation-intensive Fourier transforms, spectra, co-spectra, multiple rotations, stationarity, footprint, etc. (iv) Final fluxes, radiation, weather and soil data will

  9. Next Generation Life Support Project: Development of Advanced Technologies for Human Exploration Missions

    Science.gov (United States)

    Barta, Daniel J.

    2012-01-01

    Next Generation Life Support (NGLS) is one of several technology development projects sponsored by the National Aeronautics and Space Administration s Game Changing Development Program. NGLS is developing life support technologies (including water recovery, and space suit life support technologies) needed for humans to live and work productively in space. NGLS has three project tasks: Variable Oxygen Regulator (VOR), Rapid Cycle Amine (RCA) swing bed, and Alternative Water Processing. The selected technologies within each of these areas are focused on increasing affordability, reliability, and vehicle self sufficiency while decreasing mass and enabling long duration exploration. The RCA and VOR tasks are directed at key technology needs for the Portable Life Support System (PLSS) for an Exploration Extravehicular Mobility Unit (EMU), with focus on prototyping and integrated testing. The focus of the Rapid Cycle Amine (RCA) swing-bed ventilation task is to provide integrated carbon dioxide removal and humidity control that can be regenerated in real time during an EVA. The Variable Oxygen Regulator technology will significantly increase the number of pressure settings available to the space suit. Current spacesuit pressure regulators are limited to only two settings while the adjustability of the advanced regulator will be nearly continuous. The Alternative Water Processor efforts will result in the development of a system capable of recycling wastewater from sources expected in future exploration missions, including hygiene and laundry water, based on natural biological processes and membrane-based post treatment. The technologies will support a capability-driven architecture for extending human presence beyond low Earth orbit to potential destinations such as the Moon, near Earth asteroids and Mars.

  10. Development of high strength high toughness third generation advanced high strength steels

    Science.gov (United States)

    Martis, Codrick John

    Third generation advanced high strength steels (AHSS's) are emerging as very important engineering materials for structural applications. These steels have high specific strength and thus will contribute significantly to weight reduction in automotive and other structural component. In this investigation two such low carbon low alloy steels (LCLA) with high silicon content (1.6-2wt %) has been developed. These two steel alloys were subjected to single step and two step austempering in the temperature range of 260-399°C to obtain desired microstructures and mechanical properties. Austempering heat treatment was carried out for 2 hours in a molten salt bath. The microstructures were characterized by X-ray diffraction, scanning electron microscopy, transmission electron microscopy and optical metallography. Quantitative analysis was carried out by image analysis technique. The effect of austempering temperature on the mechanical properties of these two alloys was examined. The influence of microstructures on the mechanical properties of alloys was also studied. Austempering heat treatment resulted in fine carbide free bainitic ferrite and high carbon austenite microstructure in the samples austempered above Ms temperature, whereas tempered martensite and austenite microstructure was obtained in samples austempered below Ms temperature. Yield strength, tensile strength and fracture toughness were found to increase as the austempering temperature decreases, whereas ductility increases as the austempering temperature increases. Tensile strength in the range of 1276MPa -1658 MPa and the fracture toughness in the range of 80-141MPa√m were obtained in these two steels. Volume fractions of different phases present and their lath sizes are related to the mechanical properties. Austempered samples consisting of mixed microstructure of bainitic ferrite and tempered martensite phases resulted in the exceptional combination of strength and toughness.

  11. The development and use of radionuclide generators in nuclear medicine - recent advances and future perspectives

    International Nuclear Information System (INIS)

    Knapp, F.F. Jr.

    1998-03-01

    Although the trend in radionuclide generator research has declined, radionuclide generator systems continue to play an important role in nuclear medicine. Technetium-99m obtained from the molybdenum-99/technetium-99m generator system is used in over 80% of all diagnostic clinical studies and there is increasing interest and use of therapeutic radioisotopes obtained from generator systems. This paper focuses on a discussion of the major current areas of radionuclide generator research, and the expected areas of future research and applications

  12. Advanced Electrode Materials for High Energy Next Generation Li ion Batteries

    Science.gov (United States)

    Hayner, Cary Michael

    Lithium ion batteries are becoming an increasingly ubiquitous part of modern society. Since their commercial introduction by Sony in 1991, lithium-ion batteries have grown to be the most popular form of electrical energy storage for portable applications. Today, lithium-ion batteries power everything from cellphones and electric vehicles to e-cigarettes, satellites, and electric aircraft. Despite the commercialization of lithium-ion batteries over twenty years ago, it remains the most active field of energy storage research for its potential improvement over current technology. In order to capitalize on these opportunities, new materials with higher energy density and storage capacities must be developed. Unfortunately, most next-generation materials suffer from rapid capacity degradation or severe loss of capacity when rapidly discharged. In this dissertation, the development of novel anode and cathode materials for advanced high-energy and high-power lithium-ion batteries is reported. In particular, the application of graphene-based materials to stabilize active material is emphasized. Graphene, a unique two-dimensional material composed of atomically thin carbon sheets, has shown potential to address unsatisfactory rate capability, limited cycling performance and abrupt failure of these next-generation materials. This dissertation covers four major subjects: development of silicon-graphene composites, impact of carbon vacancies on graphene high-rate performance, iron fluoride-graphene composites, and ternary iron-manganese fluoride synthesis. Silicon is considered the most likely material to replace graphite as the anode active material for lithium-ion batteries due to its ability to alloy with large amounts of lithium, leading to significantly higher specific capacities than the graphite standard. However, Si also expands in size over 300% upon lithiation, leading to particle fracture and isolation from conductive support, resulting in cell failure within a few

  13. Hematopoietic specification from human pluripotent stem cells: current advances and challenges toward de novo generation of hematopoietic stem cells.

    Science.gov (United States)

    Slukvin, Igor I

    2013-12-12

    Significant advances in cellular reprogramming technologies and hematopoietic differentiation from human pluripotent stem cells (hPSCs) have already enabled the routine production of multiple lineages of blood cells in vitro and opened novel opportunities to study hematopoietic development, model genetic blood diseases, and manufacture immunologically matched cells for transfusion and cancer immunotherapy. However, the generation of hematopoietic cells with robust and sustained multilineage engraftment has not been achieved. Here, we highlight the recent advances in understanding the molecular and cellular pathways leading to blood development from hPSCs and discuss potential approaches that can be taken to facilitate the development of technologies for de novo production of hematopoietic stem cells.

  14. Investigation of Advanced Counterrotation Blade Configuration Concepts for High Speed Turboprop Systems. Task 3: Advanced Fan Section Grid Generator Final Report and Computer Program User's Manual

    Science.gov (United States)

    Crook, Andrew J.; Delaney, Robert A.

    1991-01-01

    A procedure is studied for generating three-dimensional grids for advanced turbofan engine fan section geometries. The procedure constructs a discrete mesh about engine sections containing the fan stage, an arbitrary number of axisymmetric radial flow splitters, a booster stage, and a bifurcated core/bypass flow duct with guide vanes. The mesh is an h-type grid system, the points being distributed with a transfinite interpolation scheme with axial and radial spacing being user specified. Elliptic smoothing of the grid in the meridional plane is a post-process option. The grid generation scheme is consistent with aerodynamic analyses utilizing the average-passage equation system developed by Dr. John Adamczyk of NASA Lewis. This flow solution scheme requires a series of blade specific grids each having a common axisymmetric mesh, but varying in the circumferential direction according to the geometry of the specific blade row.

  15. Nondestructive testing of welds in steam generators for advanced gas cooled reactors at Heyshamm II and Torness

    International Nuclear Information System (INIS)

    Parkin, K.; Bainbridge, A.; Carver, K.; Hammell, R.; Lack, B.J.

    1985-01-01

    The paper concerns non-destructive testing (NDT) of welds in advanced gas cooled steam generators for Heysham II and Torness nuclear power stations. A description is given of the steam generator. The selection of NDT techniques is also outlined, including the factors considered to ascertain the viability of a technique. Examples are given of applied NDT methods which match particular fabrication processes; these include: microfocus radiography, ultrasonic testing of austenitic tube butt welds, gamma-ray isotope projection system, surface crack detection, and automated radiography. Finally, future trends in this field of NDT are highlighted. (UK)

  16. A computer program for estimating the power-density spectrum of advanced continuous simulation language generated time histories

    Science.gov (United States)

    Dunn, H. J.

    1981-01-01

    A computer program for performing frequency analysis of time history data is presented. The program uses circular convolution and the fast Fourier transform to calculate power density spectrum (PDS) of time history data. The program interfaces with the advanced continuous simulation language (ACSL) so that a frequency analysis may be performed on ACSL generated simulation variables. An example of the calculation of the PDS of a Van de Pol oscillator is presented.

  17. PROBABILISTIC PROGRAMMING FOR ADVANCED MACHINE LEARNING (PPAML) DISCRIMINATIVE LEARNING FOR GENERATIVE TASKS (DILIGENT)

    Science.gov (United States)

    2017-11-29

    the corresponding statistical quantities is formulated according to its definition , which involves the corresponding Fredholm integral equation. This...generative and discriminative areas: • Generative models: a novel framework for most accurate computation of key statistical elements of model...and data-driven ones: • Generative models: a novel framework for most accurate computation of key statistical elements of model-driven problems (such

  18. Thermal hydraulic characteristics of a double-walled tube advanced nuclear steam generator

    International Nuclear Information System (INIS)

    Cho, S.M.; Seltzer, A.H.

    1989-01-01

    In this paper the thermal hydraulic characteristics of double-walled tube steam generator designed for sodium-cooled nuclear reactors are presented. The double-walled tube construction, along with double-barrier welds for tube-to-tubesheet joints, virtually eliminates the probability of heat transfer tube failure. Considerations are given to the use of the internal core tube, helical vane swirl generator, external protector tube, and variably perforated flow baffles to improve thermal and hydraulic performance of the steam generator. These thermal hydraulic design features with a particular reference to a 432 MW PRISM steam generator are discussed

  19. Advanced Energy Design Guide K-12: Next Generation of School Design and Operation

    Energy Technology Data Exchange (ETDEWEB)

    Torcellini, Paul A [National Renewable Energy Laboratory (NREL), Golden, CO (United States); Pless, Shanti [National Renewable Energy Laboratory (NREL), Golden, CO (United States)

    2018-01-01

    Driven by energy efficiency advances and renewable energy cost reductions, zero energy buildings are popping up all around the country. Although zero energy represents a bold paradigm shift - from buildings that consume energy to buildings that produce enough energy to meet their energy needs on an annual basis - it isn't a sudden shift. Zero energy buildings are the result of steady, incremental progress by researchers and building professionals working together to improve building energy performance. ASHRAE is taking the lead by publishing - in partnership with the American Institute of Architects (AIA), the Illuminating Engineering Society (IES), the U.S. Green Building Council (USGBC), and the U.S. Department of Energy (DOE) - a new series of advanced energy design guides (AEDGs) focused on zero energy buildings. The recently completed Advanced Energy Design Guide for K-12 School Buildings: Achieving Zero Energy (K-12 ZE AEDG) is the first in this series.

  20. Advanced life-cycle management for an increased steam generator performance

    International Nuclear Information System (INIS)

    Beck, J.; Schwarz, T.; Bouecke, R.; Schneider, V.

    2006-01-01

    High steam generators performance is a prerequisite for high plant availability and possible life time extension. During operation, the performance is reduced by fouling of the heating tubes and by corrosion, resulting on a reduction of the heat-exchange area. Such steam generator degradation problems arise from mechanical degradation and a continuous ingress of non-volatile contaminants, i.e. corrosion products and salt impurities accumulated in the steam generators. In addition, the tube scales in general affect the steam generator thermal performance, which ultimately cause a reduction of power output. AREVA applied an integrated service for utilities to evaluate all operational parameters influencing the steam generator performance. The evaluation is assisted by a systematic approach to evaluate the major steam generator operational data. The different data are structured and indexed in a Cleanling-Matrix. The result of this matrix is a quantified, dimensionless figure, given as the Fouling Index. The Fouling Index allows to monitor the condition of steam generators, compare it to other plants and, in combination with a life-time management applied at several German utilities, it allows verified statements on the past operation. Based on these data, an extrapolation of the potential additional life-time of the component is possible. As such, the Fouling Index is a valuable tool concerning life-time extension considerations. The application of the cleanliness criteria in combination with operational data with respect to life-time monitoring and improvements of steam generator performance are presented. (author)

  1. Generation Vexed: Age-Related Culture Clashes in the Advancement Office and How to Avoid Them

    Science.gov (United States)

    DiConsiglio, John

    2009-01-01

    Welcome to the Generational Wars--a workplace skirmish over everything from ties and pantyhose to flex time and Facebook. For the first time in American history, three generations are now working desk-to-desk. And each brings wildly varying views on work and life into the office. The battle lines have been drawn. On one side are the Baby Boomers,…

  2. DESIGN, FABRICATION, AND TESTING OF AN ADVANCED, NON-POLLUTING TURBINE DRIVE GAS GENERATOR

    International Nuclear Information System (INIS)

    Unknown

    2002-01-01

    The objectives of this report period were to complete the development of the Gas Generator design, which was done; fabricate and test of the non-polluting unique power turbine drive gas Gas Generator, which has been postponed. Focus during this report period has been to complete the brazing and bonding necessary to fabricate the Gas Generator hardware, continue making preparations for fabricating and testing the Gas Generator, and continuing the fabrication of the Gas Generator hardware and ancillary hardware in preparation for the test program. Fabrication is more than 95% complete and is expected to conclude in early May 2002. the test schedule was affected by relocation of the testing to another test supplier. The target test date for hot fire testing is now not earlier than June 15, 2002

  3. Aspects of rationalization when introducing nuclear reactors of an advanced generation into the market

    International Nuclear Information System (INIS)

    Marnet, C.

    1980-01-01

    This lecture deals with the possibilities and necessities of promoting the introduction of advanced reactors, especially high temperature reactors, into the market. The statements of this and another lecture are specified and continued in a discussion which was recorded subsequently. (UA) [de

  4. How Syntactic Reasoners Can Develop Understanding, Evaluate Conjectures, and Generate Counterexamples in Advanced Mathematics

    Science.gov (United States)

    Weber, Keith

    2009-01-01

    This paper presents a case study of a highly successful student whose exploration of an advanced mathematical concept relies predominantly on syntactic reasoning, such as developing formal representations of mathematical ideas and making logical deductions. This student is observed as he learns a new mathematical concept and then completes…

  5. Optical Far-IR Wave Generation - State-of-the-Art and Advanced Device Structures

    DEFF Research Database (Denmark)

    Krozer, Viktor; Leone, B.; Roskos, H.

    2004-01-01

    and experimental results selected for medium to short term development. These technologies include advanced p-i-n photomixer with superlattice structures and, THz quantum cascade lasers. Recent results achieved in these fields will be put into the potential perspective for the respective technology in the future....

  6. Commercializing the next generation: the AP600 advanced simplified nuclear power plant

    International Nuclear Information System (INIS)

    Bruschi, H.J.

    1994-01-01

    Today, government and industry are working together on advanced nuclear power plant designs that take advantage of valuable lessons learned from the experience to date and promise to reconcile the demands of economic expansion with the laws of environmental protection. In the U.S., the Department of Energy (DOE) and the Electric Power Research Institute (EPRI) initiated a design certification program in 1989 to develop and commercialize advanced light water reactors (ALWRs) for the next round of power plant construction. Advanced, simplified technology is one approach under development to end the industry's search for a simpler, more forgiving, and less costly reactor. As part of this program, Westinghouse is developing the AP600, a new standard 600 MWe advanced, simplified plant. The design strikes a balance between the use of proven technology and new approaches. The result is a greatly streamlined plant that can meet safety regulations and reliability requirements, be economically competitive, and promote broader public confidence in nuclear energy. 1 fig

  7. Performance of the Harmony™ behind-the-ear processor with the first generation of Advanced Bionics™ implant systems.

    Science.gov (United States)

    Brendel, Martina; Rottmann, Tobias; Lenarz, Thomas; Buechner, Andreas

    2013-01-01

    When new cochlear implant (CI) sound processors are being introduced by the manufacturers, usually the newest generation implants benefit first from the new technology in order to release the full potential of the new hardware. Subsequently, for the Advanced Bionics system the Harmony behind-the-ear processor was only compatible to the newer generation implants, i.e. the CII and HiRes90K, at the time of market release. After further development of a new Digital Signal Processing code the Harmony could also support the first implant generation, the 'C1' (Clarion 1.0 and 1.2). This study reports on a field trial with a new sound processor designed to be used with older generation CIs from Advanced Bionics, focussing on ergonomic and performance benefits. Speech perception tests (Freiburger monosyllables, HSM sentence tests) were performed at a baseline appointment with the subject's clinical processor, followed by the fitting of the Harmony. After a 1 month take-home period the tests were repeated with the Harmony. Additionally, subjective evaluation through questionnaires and a structured interview were administered after upgrading to the sound processor 'C1 Harmony'. Adult users of Advanced Bionics C1 series CIs (n = 29) participated in this study. The new processor provided superior performance in many, though not all, of the speech recognition measurements. Subjective reports indicated certain practical benefits from the new processor, particularly for previous users of body-worn processors. Overall, 80% of the subjects preferred the new processor. The positive outcomes from this trial have resulted in the decision to make the new C1 Harmony processor available to all existing users of the early C1 devices.

  8. Next generation grinding spindle for cost-effective manufacture of advanced ceramic components

    Energy Technology Data Exchange (ETDEWEB)

    Kovach, J.A.; Laurich, M.A.

    2000-01-01

    Finish grinding of advanced structural ceramics has generally been considered an extremely slow and costly process. Recently, however, results from the High-Speed, Low-Damage (HSLD) program have clearly demonstrated that numerous finish-process performance benefits can be realized by grinding silicon nitride at high wheel speeds. A new, single-step, roughing-process capable of producing high-quality silicon nitride parts at high material removal rates while dramatically reducing finishing costs has been developed.

  9. Implementation of an advanced digital feedwater control system at the Prairie Island nuclear generating station

    International Nuclear Information System (INIS)

    Paris, R.E.; Gaydos, K.A.; Hill, J.O.; Whitson, S.G.; Wirkkala, R.

    1990-05-01

    EPRI Project RP2126-4 was a cooperative effort between TVA, EPRI, and Westinghouse which resulted in the demonstration of a prototype of a full range, fully automatic feedwater control system, using fault tolerant digital technology, at the TVA Sequoyah simulator site. That prototype system also included advanced signal validation algorithms and an advanced man-machine interface that used CRT-based soft-control technology. The Westinghouse Advanced Digital Feedwater Control System (ADFCS) upgrade, which contains elements that were part of that prototype system, has since been installed at Northern States Power's Prairie Island Unit 2. This upgrade was very successful due to the use of an advanced control system design and the execution of a well coordinated joint effort between the utility and the supplier. The project experience is documented in this report to help utilities evaluate the technical implications of such a project. The design basis of the Prairie Island ADFCS signal validation for input signal failure fault tolerance is outlined first. Features of the industry-proven system control algorithms are then described. Pre-shipment hardware-in-loop and factory acceptance testing of the Prairie Island system are summarized. Post-shipment site testing, including preoperational and plant startup testing, is also summarized. Plant data from the initial system startup is included. The installation of the Prairie Island ADFCS is described, including both the feedwater control instrumentation and the control board interface. Modification of the plant simulator and operator and I ampersand C personnel training are also discussed. 6 refs., 14 figs., 3 tabs

  10. Multiscale Modeling of the Deformation of Advanced Ferritic Steels for Generation IV Nuclear Energy

    Energy Technology Data Exchange (ETDEWEB)

    Nasr M. Ghoniem; Nick Kioussis

    2009-04-18

    The objective of this project is to use the multi-scale modeling of materials (MMM) approach to develop an improved understanding of the effects of neutron irradiation on the mechanical properties of high-temperature structural materials that are being developed or proposed for Gen IV applications. In particular, the research focuses on advanced ferritic/ martensitic steels to enable operation up to 650-700°C, compared to the current 550°C limit on high-temperature steels.

  11. Advanced Corrosion-Resistant Zr Alloys for High Burnup and Generation IV Applications

    International Nuclear Information System (INIS)

    Arthur Motta; Yong Hwan Jeong; R.J. Comstock; G.S. Was; Y.S. Kim

    2006-01-01

    The objective of this collaboration between four institutions in the US and Korea is to demonstrate a technical basis for the improvement of the corrosion resistance of zirconium-based alloys in more extreme operating environments (such as those present in severe fuel duty, cycles high burnup, boiling, aggressive chemistry) and to investigate the feasibility (from the point of view of corrosion rate) of using advanced zirconium-based alloys in a supercritical water environment

  12. A study of some recent advances in the concept and design of MHD generators

    International Nuclear Information System (INIS)

    Vakilian, M.

    1976-02-01

    Direct conversion of energy and high temperature working fluid making Magnetohydrodynamics (MHD) power plants potentially much more efficient than steam power stations. The study indicates an overall efficiency of 50% to 60%. This compares with most modern fossil-fuel plants at 40% efficiency. Advances in design and construction of experimental and commercial MHD plants developed in various countries are presented. Environmental effects and advantages of the MHD power plants over the more conventional fossil and nuclear plants are discussed

  13. Development of Advanced Fourth Generation Light Sources for the Accelerator Science Laboratory

    OpenAIRE

    Chanwattana, Thakonwat; Bartolini, Riccardo; Seryi, Andrei; Tsesmelis, Emmanuel

    2015-01-01

    The John Adams Institute for Accelerator Science (JAI) has proposed the realisation of the Accelerator Science Laboratory (ASL) at the University of Oxford as a facility for the development of advanced compact light sources enabling accelerator science research and applications. The installation of a compact light source in the ASL is planned with two options for the accelerating technologies. Firstly, a conventional RF based accelerator is considered to be a driver for a short pulse THz cohe...

  14. Analysis of Advanced Fuel Assemblies and Core Designs for the Current and Next Generations of LWRs

    International Nuclear Information System (INIS)

    Ragusa, Jean; Vierow, Karen

    2011-01-01

    The objective of the project is to design and analyze advanced fuel assemblies for use in current and future light water reactors and to assess their ability to reduce the inventory of transuranic elements, while preserving operational safety. The reprocessing of spent nuclear fuel can delay or avoid the need for a second geological repository in the US. Current light water reactor fuel assembly designs under investigation could reduce the plutonium inventory of reprocessed fuel. Nevertheless, these designs are not effective in stabilizing or reducing the inventory of minor actinides. In the course of this project, we developed and analyzed advanced fuel assembly designs with improved thermal transmutation capability regarding transuranic elements and especially minor actinides. These designs will be intended for use in thermal spectrum (e.g., current and future fleet of light water reactors in the US). We investigated various fuel types, namely high burn-up advanced mixed oxides and inert matrix fuels, in various geometrical designs that are compliant with the core internals of current and future light water reactors. Neutronic/thermal hydraulic effects were included. Transmutation efficiency and safety parameters were used to rank and down-select the various designs.

  15. Analysis of Advanced Fuel Assemblies and Core Designs for the Current and Next Generations of LWRs

    Energy Technology Data Exchange (ETDEWEB)

    Ragusa, Jean; Vierow, Karen

    2011-09-01

    The objective of the project is to design and analyze advanced fuel assemblies for use in current and future light water reactors and to assess their ability to reduce the inventory of transuranic elements, while preserving operational safety. The reprocessing of spent nuclear fuel can delay or avoid the need for a second geological repository in the US. Current light water reactor fuel assembly designs under investigation could reduce the plutonium inventory of reprocessed fuel. Nevertheless, these designs are not effective in stabilizing or reducing the inventory of minor actinides. In the course of this project, we developed and analyzed advanced fuel assembly designs with improved thermal transmutation capability regarding transuranic elements and especially minor actinides. These designs will be intended for use in thermal spectrum (e.g., current and future fleet of light water reactors in the US). We investigated various fuel types, namely high burn-up advanced mixed oxides and inert matrix fuels, in various geometrical designs that are compliant with the core internals of current and future light water reactors. Neutronic/thermal hydraulic effects were included. Transmutation efficiency and safety parameters were used to rank and down-select the various designs.

  16. Microbial electricity generation in rice paddy fields: recent advances and perspectives in rhizosphere microbial fuel cells.

    Science.gov (United States)

    Kouzuma, Atsushi; Kaku, Nobuo; Watanabe, Kazuya

    2014-12-01

    Microbial fuel cells (MFCs) are devices that use living microbes for the conversion of organic matter into electricity. MFC systems can be applied to the generation of electricity at water/sediment interfaces in the environment, such as bay areas, wetlands, and rice paddy fields. Using these systems, electricity generation in paddy fields as high as ∼80 mW m(-2) (based on the projected anode area) has been demonstrated, and evidence suggests that rhizosphere microbes preferentially utilize organic exudates from rice roots for generating electricity. Phylogenetic and metagenomic analyses have been conducted to identify the microbial species and catabolic pathways that are involved in the conversion of root exudates into electricity, suggesting the importance of syntrophic interactions. In parallel, pot cultures of rice and other aquatic plants have been used for rhizosphere MFC experiments under controlled laboratory conditions. The findings from these studies have demonstrated the potential of electricity generation for mitigating methane emission from the rhizosphere. Notably, however, the presence of large amounts of organics in the rhizosphere drastically reduces the effect of electricity generation on methane production. Further studies are necessary to evaluate the potential of these systems for mitigating methane emission from rice paddy fields. We suggest that paddy-field MFCs represent a promising approach for harvesting latent energy of the natural world.

  17. Next Generation Respiratory Viral Vaccine System: Advanced and Emerging Bioengineered Human Lung Epithelia Model (HLEM) Organoid Technology

    Science.gov (United States)

    Goodwin, Thomas J.; Schneider, Sandra L.; MacIntosh, Victor; Gibbons, Thomas F.

    2010-01-01

    Acute respiratory infections, including pneumonia and influenza, are the S t" leading cause of United States and worldwide deaths. Newly emerging pathogens signaled the need for an advanced generation of vaccine technology.. Human bronchial-tracheal epithelial tissue was bioengineered to detect, identify, host and study the pathogenesis of acute respiratory viral disease. The 3-dimensional (3D) human lung epithelio-mesechymal tissue-like assemblies (HLEM TLAs) share characteristics with human respiratory epithelium: tight junctions, desmosomes, microvilli, functional markers villin, keratins and production of tissue mucin. Respiratory Syntial Virus (RSV) studies demonstrate viral growth kinetics and membrane bound glycoproteins up to day 20 post infection in the human lung-orgainoid infected cell system. Peak replication of RSV occurred on day 10 at 7 log10 particles forming units per ml/day. HLEM is an advanced virus vaccine model and biosentinel system for emergent viral infectious diseases to support DoD global surveillance and military readiness.

  18. Advanced Machine Learning for Classification, Regression, and Generation in Jet Physics

    CERN Multimedia

    CERN. Geneva

    2017-01-01

    There is a deep connection between machine learning and jet physics - after all, jets are defined by unsupervised learning algorithms. Jet physics has been a driving force for studying modern machine learning in high energy physics. Domain specific challenges require new techniques to make full use of the algorithms. A key focus is on understanding how and what the algorithms learn. Modern machine learning techniques for jet physics are demonstrated for classification, regression, and generation. In addition to providing powerful baseline performance, we show how to train complex models directly on data and to generate sparse stacked images with non-uniform granularity.

  19. The effect of advanced technology on the second-generation SST

    Science.gov (United States)

    Coen, P. G.

    1986-01-01

    Technological developments that promise to substantially increase the efficiency of next-generation subsonic commercial aircraft, together with additional developments in supersonic aircraft aerodynamics, structures and propulsion systems, are presently evaluated in order to project the extent of performance and economic improvement obtainable for a future SST by comparison to the Concorde SST. It is demonstrated that the second-generation SST projected will double passenger-carrying capacity from 100 for the Concorde to 200, despite reducing takeoff gross weight from 400,000 to 321,000 lbs and extending range by some 2000 nm.

  20. Advanced Wind Turbine Program Next Generation Turbine Development Project: June 17, 1997--April 30, 2005

    Energy Technology Data Exchange (ETDEWEB)

    GE Wind Energy, LLC

    2006-05-01

    This document reports the technical results of the Next Generation Turbine Development Project conducted by GE Wind Energy LLC. This project is jointly funded by GE and the U.S. Department of Energy's National Renewable Energy Laboratory.The goal of this project is for DOE to assist the U.S. wind industry in exploring new concepts and applications of cutting-edge technology in pursuit of the specific objective of developing a wind turbine that can generate electricity at a levelized cost of energy of $0.025/kWh at sites with an average wind speed of 15 mph (at 10 m height).

  1. The Lightweight Integrated Solar Array and Transceiver (LISA-T): Second Generation Advancements and the Future of SmallSat Power Generation

    Science.gov (United States)

    Carr, John A.; Boyd, Darren; Martinez, Armando; SanSoucie, Michael; Johnson, Les; Laue, Greg; Farmer, Brandon; Smith, Joseph C.; Robertson, Barrett; Johnson, Mark

    2016-01-01

    This paper describes the second generation advancements of the Lightweight Integrated Solar Array and Transceiver (LISA-T) currently being developed at NASA's Marshall Space Flight Center. LISA-T is a launch stowed, orbit deployed array on which thin-film photovoltaic and antenna elements are embedded. Inherently, small satellites are limited in surface area, volume, and mass allocation; driving competition between power, communications, and GN&C (guidance navigation and control) subsystems. This restricts payload capability and limits the value of these low-cost satellites. LISA-T is addressing this issue, deploying large-area arrays from a reduced volume and mass envelope - greatly enhancing power generation and communications capabilities of small spacecraft. A matrix of options are in development, including planar (pointed) and omnidirectional (non-pointed) arrays. The former is seeking the highest performance possible while the latter is seeking GN&C simplicity. In both cases, power generation ranges from tens of watts to several hundred with an expected specific power >250W/kg and a stowed power density >200kW/m(sub 3). Options for leveraging both high performance, 'typical cost' triple junction thin-film solar cells as well as moderate performance, low cost cells are being developed. Alongside, both UHF (ultra high frequency) and S-band antennas are being integrated into the array to move their space claim away from the spacecraft and open the door for omnidirectional communications and electronically steered phase arrays.

  2. Integrity evaluation for steam generator tube of system integrated modular advanced reactor

    International Nuclear Information System (INIS)

    Kim, J. S.; Jin, T. E.; Jeong, M. J.; Choi, Y. H.; Jeo, J. C.

    2003-01-01

    In this study, the structural integrity for SG tube of system integrated modular advanced reactor, which is subjected to dominant external pressure as well as helical type, is evaluated using the commercial finite element package ABAQUS and the American petrochemical industry code API 579 Appendix B. First of all, the crack behavior under the assumption of local heating is assessed using ABAQUS. And, the buckling behavior of tube with 40% wall thinning is assessed using API 579 Appendix B. As a result, it is found that the crack closure phenomenon occurs under external pressure and the buckling doesn't occur even if 40% wall thinning exists in tube

  3. ASGARD - Advanced fuelS for Generation IV reActors: Reprocessing and Dissolution

    International Nuclear Information System (INIS)

    Ekberg, C.; Retegan, T.; De Visser-Tynova, E.; Wallenius, J.; Sarsfield, M.

    2013-01-01

    Conclusion: Thanks to its interdiciplinary nature ASGARD has created a common platform for many aspects of novel nuclear fuel cycles, 25% into the project everything is running according to plan with significant advances in most domains. The training and education scheme used in ASGARD has already been successfully implemented allowing young scientists in the field to present their results internationally and also visit other ASGARD labs. The future collaboration with e.g. SACESS and CINCH II will enable the creation of significant added value to the communities involved. More will come. We have only begun.....

  4. Data Generation in the Discovery Sciences--Learning from the Practices in an Advanced Research Laboratory

    Science.gov (United States)

    Roth, Wolff-Michael

    2013-01-01

    General scientific literacy includes understanding the grounds on which scientific claims are based. The measurements scientists make and the data that they produce from them generally constitute these grounds. However, the nature of data generation has received relatively little attention from those interested in teaching science through inquiry.…

  5. Development and field validation of advanced array probes for steam generator inspection

    International Nuclear Information System (INIS)

    Dodd, C.V.; Pate, J.R.

    1995-01-01

    The aging of the steam generators at the nation's nuclear power plants has led to the appearance of new forms of degradation in steam generator tubes and an increase in the frequency of forced outages due to major tube leak events. The eddy-current techniques currently being used for the inspection of steam generator tubing are no longer adequate to ensure that flaws will be detected before they lead to a shutdown of the plant. To meet the need for a fast and reliable method of inspection, ORNL has designed a 16-coil eddy-current array probe which combines an inspection speed similar to that of the bobbin coil with a sensitivity to cracks of any orientation similar to the rotating pancake coil. In addition, neural network and least square methods have been developed for the automatic analysis of the data acquired with the new probes. The probes and analysis software have been tested at two working steam generators where we have found an increase in the signal-to-noise ratio of a factor of five an increase in the inspection speed of a factor of 75 over the rotating pancake coil which maintaining similar detection and characterization capabilities

  6. Cascaded interactions between Raman induced solitons and dispersive waves in photonic crystal fibers at the advanced stage of supercontinuum generation.

    Science.gov (United States)

    Driben, Rodislav; Mitschke, Fedor; Zhavoronkov, Nickolai

    2010-12-06

    The complex mechanism of multiple interactions between solitary and dispersive waves at the advanced stage of supercontinuum generation in photonic crystal fiber is studied in experiment and numerical simulations. Injection of high power negatively chirped pulses near zero dispersion frequency results in an effective soliton fission process with multiple interactions between red shifted Raman solitons and dispersive waves. These interactions may result in relative acceleration of solitons with further collisions between them of quasi-elastic or quasi-plastic kinds. In the spectral domain these processes result in enhancement of certain wavelength regions within the spectrum or development of a new significant band at the long wavelength side of the spectrum.

  7. Accelerated development of Zr-containing new generation ferritic steels for advanced nuclear reactors

    Energy Technology Data Exchange (ETDEWEB)

    Tan, Lizhen [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Yang, Ying [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Sridharan, K. [Univ. of Wisconsin, Madison, WI (United States)

    2015-12-01

    The mission of the Nuclear Energy Enabling Technologies (NEET) program is to develop crosscutting technologies for nuclear energy applications. Advanced structural materials with superior performance at elevated temperatures are always desired for nuclear reactors, which can improve reactor economics, safety margins, and design flexibility. They benefit not only new reactors, including advanced light water reactors (LWRs) and fast reactors such as the sodium-cooled fast reactor (SFR) that is primarily designed for management of high-level wastes, but also life extension of the existing fleet when component exchange is needed. Developing and utilizing the modern materials science tools (experimental, theoretical, and computational tools) is an important path to more efficient alloy development and process optimization. The ultimate goal of this project is, with the aid of computational modeling tools, to accelerate the development of Zr-bearing ferritic alloys that can be fabricated using conventional steelmaking methods. The new alloys are expected to have superior high-temperature creep performance and excellent radiation resistance as compared to Grade 91. The designed alloys were fabricated using arc-melting and drop-casting, followed by hot rolling and conventional heat treatments. Comprehensive experimental studies have been conducted on the developed alloys to evaluate their hardness, tensile properties, creep resistance, Charpy impact toughness, and aging resistance, as well as resistance to proton and heavy ion (Fe2+) irradiation.

  8. Advances in clinical next-generation sequencing: target enrichment and sequencing technologies.

    Science.gov (United States)

    Ballester, Leomar Y; Luthra, Rajyalakshmi; Kanagal-Shamanna, Rashmi; Singh, Rajesh R

    2016-01-01

    The huge parallel sequencing capabilities of next generation sequencing technologies have made them the tools of choice to characterize genomic aberrations for research and diagnostic purposes. For clinical applications, screening the whole genome or exome is challenging owing to the large genomic area to be sequenced, associated costs, complexity of data, and lack of known clinical significance of all genes. Consequently, routine screening involves limited markers with established clinical relevance. This process, referred to as targeted genome sequencing, requires selective enrichment of the genomic areas comprising these markers via one of several primer or probe-based enrichment strategies, followed by sequencing of the enriched genomic areas. Here, the authors review current target enrichment approaches and next generation sequencing platforms, focusing on the underlying principles, capabilities, and limitations of each technology along with validation and implementation for clinical testing.

  9. Emerging applications of advanced fuels for energy generation and transmutation. Overview of IAEA activities

    International Nuclear Information System (INIS)

    Pong Eil Juhn; Arkhipov, V.

    1996-01-01

    Nuclear power generation is an established part of the world's electricity mix. However, the highly radioactive waste generated during power production is of great concern of public perception of nuclear energy. In order for nuclear power to realize its full potential as a major energy source for the entire world, there must be a safe and effective way to deal with this waste. Therefore, science must come to the rescue in the form of new, more effective technology aimed at reducing the amount of long-lived radioactive waste and eliminating nuclear weapons' grade material through transmutation of these isotopes in fission reactors or accelerators. In the framework of IAEA activities on the use of this new technologies the Agency has periodically review and assess the current status of the new fuel cycles, its applications worldwide, its economic benefits, and its perceived advantages vis-a-vis other nuclear fuel cycles. (author)

  10. Simulation of Electric Faults in Doubly-Fed Induction Generators Employing Advanced Mathematical Modelling

    DEFF Research Database (Denmark)

    Martens, Sebastian; Mijatovic, Nenad; Holbøll, Joachim

    2015-01-01

    Efficient fault detection in generators often require prior knowledge of fault behavior, which can be obtained from theoretical analysis, often carried out by using discrete models of a given generator. Mathematical models are commonly represented in the DQ0 reference frame, which is convenient...... in many areas of electrical machine analysis. However, for fault investigations, the phase-coordinate representation has been found more suitable. This paper presents a mathematical model in phase coordinates of the DFIG with two parallel windings per rotor phase. The model has been implemented in Matlab...... and its properties in context of fault simulations and investigations has been investigated. Some of the most common faults have been simulated, namely broken rotor bars or windings, dynamic eccentricities and stator phase winding short circuits. These fault conditions propagate to the stator current...

  11. Organic materials for second-harmonic generation: advances in relating structure to function.

    Science.gov (United States)

    Cole, Jacqueline M

    2003-12-15

    The relationships between molecular structure and the nonlinear optical phenomenon second-harmonic generation (SHG) are discussed. New-found relationships built up from basic structural axioms that were deduced in the 1970s and 1980s are the particular focus of this article, using structural results from X-ray and neutron-diffraction studies. The molecular and supramolecular manifestations of the SHG effect are borne out, although ways to optimize the effect on the molecular scale feature predominantly, since control of SHG on the supramolecular scale remains difficult given present limitations. The use of a variety of templates to generate head-to-tail oriented host-guest species thereby bypassing such limitations is described. The paper concludes with a look ahead at next generation 'octupolar' SHG-active compounds, the prediction of new series of SHG-active compounds via data-mining computational procedures, and developments in diffraction technology that may enable structural movies of a molecule to be captured during the SHG process. A practical assessment of the viability of organic SHG materials for industrial application is reviewed with a positive outcome, thus indicating a promising future for organic SHG materials.

  12. Diagnostic of corrosion defects in steam generator tubes using advanced signal processing from Eddy current testing

    International Nuclear Information System (INIS)

    Formigoni, Andre L.; Lopez, Luiz A.N.M.; Ting, Daniel K.S.

    2009-01-01

    Recently, the Brazilian Angra I PWR nuclear power plant went into a programmed shutdown for substitution of its Steam Generator (SG) which life was shortened due to stress corrosion in its tubes. The total cost of investment were around R$724 million. The signals generated during an Eddy-current Testing (ECT) inspection in SG tubes of nuclear plant allows for the localization and dimensioning of defects in the tubes. The defects related with corrosion generate complex signals that are difficult to analyze and are the most common cause in SG replacement in nuclear power plants around the world. The objective of this paper is the development of a methodology that allows for the characterization of corrosion signals by ECT inspections applied in the heat exchangers tubes of SG of a nuclear power plant. In this present work, the aim is to investigate distributed type defects by inducing controlled corrosion in sample tubes of different materials The ECT signals obtained from these samples tubes with corrosion implanted, will be analyzed using Zetec ECT equipment, the MIZ-17ET and its probes. The data acquisition will use a NI PC A/D CARD 700 card and the LabVIEW program. Subsequently, we will apply mathematical tools for signal processing like time windowed Fast Fourier transforms and Wavelets transforms, in MATLAB platform, which will allow effectiveness to remove the noises and to extract representative characteristics for the defect being analyzed. Previously obtained results as well as the proposal for the future work will be presented. (author)

  13. Current advances in the generation of human iPS cells: implications in cell-based regenerative medicine.

    Science.gov (United States)

    Revilla, Ana; González, Clara; Iriondo, Amaia; Fernández, Bárbara; Prieto, Cristina; Marín, Carlos; Liste, Isabel

    2016-11-01

    Over the last few years, the generation of induced pluripotent stem cells (iPSCs) from human somatic cells has proved to be one of the most potentially useful discoveries in regenerative medicine. iPSCs are becoming an invaluable tool to study the pathology of different diseases and for drug screening. However, several limitations still affect the possibility of applying iPS cell-based technology in therapeutic prospects. Most strategies for iPSCs generation are based on gene delivery via retroviral or lentiviral vectors, which integrate into the host's cell genome, causing a remarkable risk of insertional mutagenesis and oncogenic transformation. To avoid such risks, significant advances have been made with non-integrative reprogramming strategies. On the other hand, although many different kinds of somatic cells have been employed to generate iPSCs, there is still no consensus about the ideal type of cell to be reprogrammed. In this review we present the recent advances in the generation of human iPSCs, discussing their advantages and limitations in terms of safety and efficiency. We also present a selection of somatic cell sources, considering their capability to be reprogrammed and tissue accessibility. From a translational medicine perspective, these two topics will provide evidence to elucidate the most suitable combination of reprogramming strategy and cell source to be applied in each human iPSC-based therapy. The wide variety of diseases this technology could treat opens a hopeful future for regenerative medicine. Copyright © 2015 John Wiley & Sons, Ltd. Copyright © 2015 John Wiley & Sons, Ltd.

  14. Measurements of nonlinear harmonic generation at the Advanced Photon Source's SASE FEL

    CERN Document Server

    Biedron, S G; Borland, M; Dejus, Roger J; Den Hartog, P K; Erdmann, M; Fawley, W M; Freund, H P; Gluskin, E; Huang, Z; Kim, K J; Lewellen, J W; Li, Y; Lumpkin, Alex H; Milton, S V; Moog, E; Nassiri, A; Sajaev, Vadim; Wiemerslage, G; Yang, B X

    2002-01-01

    SASE saturation was recently achieved at the Advanced Photon Source's SASE FEL in the low-energy undulator test line at 530 nm and 385 nm. The electron beam microbunching becomes more and more prominent until saturation is achieved. This bunching causes nonlinear harmonic emission that extends the usefulness of a SASE system in achieving shorter FEL wavelengths for the same electron beam energy. We have investigated the intensity of the fundamental and second harmonic undulator radiation as a function of distance along the undulator line and present the experimental results and compare them to numerical simulations. In addition, we have measured the single-shot second harmonic spectra as well as the simultaneous fundamental and second harmonic spectra and present the experimental results.

  15. Advanced controls for stability assessment of solar dynamics space power generation

    Science.gov (United States)

    Momoh, James A.; Anwah, Nnamdi A.

    1995-01-01

    In support of the power requirements for the Space Station Alpha (SSA), a joint program by the U.S. and Russia for a permanently manned space station to be launched into orbit by 1998, a robust control scheme is needed to assure the stability of the rotating machines that will be integrated into the power subsystem. A framework design and systems studies for modeling and analysis is presented. It employs classical d-q axes machine model with voltage/frequency dependent loads. To guarantee that design requirements and necessary trade studies are done, a functional analysis tool CORE is used for the study. This provides us with different control options for stability assessment. Initial studies and recommendations using advanced simulation tools are also presented. The benefits of the stability/control scheme for evaluating future designs and power management are discussed.

  16. Research and development of novel advanced materials for next-generation collimators

    CERN Document Server

    Bertarelli, A; Carra, F; Dallocchio, A; Gil Costa, M; Mariani, N

    2011-01-01

    The study of innovative collimators is essential to handle the high energy particle beams required to explore unknown territory in basic research. This calls for the development of novel advanced materials, as no existing metal-based or carbon-based material possesses the combination of physical, thermal, electrical and mechanical properties, imposed by collimator extreme working conditions. A new family of materials, with promising features, has been identified: metal-diamond composites. These materials are to combine the outstanding thermal and physical properties of diamond with the electrical and mechanical properties of metals. The best candidates are Copper-Diamond (Cu-CD) and Molybdenum-Diamond (Mo-CD). In particular, Mo-CD may provide interesting properties as to mechanical strength, melting temperature, thermal shock resistance and, thanks to its balanced material density, energy absorption. The research program carried out on these materials at CERN and collaborating partners is presented, mainly fo...

  17. Career Advancement: Meeting the Challenges Confronting the Next Generation of Endocrinologists and Endocrine Researchers.

    Science.gov (United States)

    Santen, Richard J; Joham, Anju; Fishbein, Lauren; Vella, Kristen R; Ebeling, Peter R; Gibson-Helm, Melanie; Teede, Helena

    2016-12-01

    Challenges and opportunities face the next generation (Next-Gen) of endocrine researchers and clinicians, the lifeblood of the field of endocrinology for the future. A symposium jointly sponsored by The Endocrine Society and the Endocrine Society of Australia was convened to discuss approaches to addressing the present and future Next-Gen needs. Data collection by literature review, assessment of previously completed questionnaires, commissioning of a new questionnaire, and summarization of symposium discussions were studied. Next-Gen endocrine researchers face diminishing grant funding in inflation-adjusted terms. The average age of individuals being awarded their first independent investigator funding has increased to age 45 years. For clinicians, a workforce gap exists between endocrinologists needed and those currently trained. Clinicians in practice are increasingly becoming employees of integrated hospital systems, resulting in greater time spent on nonclinical issues. Workforce data and published reviews identify challenges specifically related to early career women in endocrinology. Strategies to Address Issues: Recommendations encompassed the areas of grant support for research, mentoring, education, templates for career development, specific programs for Next-Gen members by senior colleagues as outlined in the text, networking, team science, and life/work integration. Endocrine societies focusing on Next-Gen members provide a powerful mechanism to support these critical areas. A concerted effort to empower, train, and support the next generation of clinical endocrinologists and endocrine researchers is necessary to ensure the viability and vibrancy of our discipline and to optimize our contributions to improving health outcomes. Collaborative engagement of endocrine societies globally will be necessary to support our next generation moving forward.

  18. Advanced modelling of doubly fed induction generator wind turbine under network disturbance

    DEFF Research Database (Denmark)

    Seman, S.; Iov, Florin; Niiranen, J.

    This paper presents a variable speed wind turbine simulator. The simulator is used for a 2 MW wind turbine transient behavior study during a short-term symmetrical network disturbance. The mechanical part of wind turbine model consists of the rotor aerodynamic model, the wind turbine control...... and the drive train model. The Doubly Fed Induction Generator (DFIG) is represented by an analytical two-axis model with constant lumped parameters and by Finite Element Method (FEM) based model. The model of the DFIG is coupled with the model of the passive crowbar protected and DTC controlled frequency...

  19. Advances in high-order harmonic generation sources for time-resolved investigations

    Energy Technology Data Exchange (ETDEWEB)

    Reduzzi, Maurizio [Dipartimento di Fisica, Politecnico di Milano, Piazza Leonardo da Vinci 32, 20133 Milano (Italy); Institute of Photonics and Nanotechnologies, CNR-IFN, Piazza Leonardo da Vinci 32, 20133 Milano (Italy); Carpeggiani, Paolo [Dipartimento di Fisica, Politecnico di Milano, Piazza Leonardo da Vinci 32, 20133 Milano (Italy); Kühn, Sergei [ELI-ALPS, ELI-Hu Kft., Dugonics ter 13, H-6720 Szeged (Hungary); Calegari, Francesca [Institute of Photonics and Nanotechnologies, CNR-IFN, Piazza Leonardo da Vinci 32, 20133 Milano (Italy); Nisoli, Mauro; Stagira, Salvatore [Dipartimento di Fisica, Politecnico di Milano, Piazza Leonardo da Vinci 32, 20133 Milano (Italy); Institute of Photonics and Nanotechnologies, CNR-IFN, Piazza Leonardo da Vinci 32, 20133 Milano (Italy); Vozzi, Caterina [Institute of Photonics and Nanotechnologies, CNR-IFN, Piazza Leonardo da Vinci 32, 20133 Milano (Italy); Dombi, Peter [ELI-ALPS, ELI-Hu Kft., Dugonics ter 13, H-6720 Szeged (Hungary); Wigner Research Center for Physics, 1121 Budapest (Hungary); Kahaly, Subhendu [ELI-ALPS, ELI-Hu Kft., Dugonics ter 13, H-6720 Szeged (Hungary); Tzallas, Paris; Charalambidis, Dimitris [ELI-ALPS, ELI-Hu Kft., Dugonics ter 13, H-6720 Szeged (Hungary); Foundation for Research and Technology – Hellas, Institute of Electronic Structure and Lasers, P.O. Box 1527, GR-711 10 Heraklion, Crete (Greece); Varju, Katalin [ELI-ALPS, ELI-Hu Kft., Dugonics ter 13, H-6720 Szeged (Hungary); Department of Optics and Quantum Electronics, University of Szeged, Dóm tér 9, 6720 Szeged (Hungary); Osvay, Karoly [ELI-ALPS, ELI-Hu Kft., Dugonics ter 13, H-6720 Szeged (Hungary); and others

    2015-10-15

    We review the main research directions ongoing in the development of extreme ultraviolet sources based on high-harmonic generation for the synthesization and application of trains and isolated attosecond pulses to time-resolved spectroscopy. A few experimental and theoretical works will be discussed in connection to well-established attosecond techniques. In this context, we present the unique possibilities offered for time-resolved investigations on the attosecond timescale by the new Extreme Light Infrastructure Attosecond Light Pulse Source, which is currently under construction.

  20. Advances in high-order harmonic generation sources for time-resolved investigations

    International Nuclear Information System (INIS)

    Reduzzi, Maurizio; Carpeggiani, Paolo; Kühn, Sergei; Calegari, Francesca; Nisoli, Mauro; Stagira, Salvatore; Vozzi, Caterina; Dombi, Peter; Kahaly, Subhendu; Tzallas, Paris; Charalambidis, Dimitris; Varju, Katalin; Osvay, Karoly

    2015-01-01

    We review the main research directions ongoing in the development of extreme ultraviolet sources based on high-harmonic generation for the synthesization and application of trains and isolated attosecond pulses to time-resolved spectroscopy. A few experimental and theoretical works will be discussed in connection to well-established attosecond techniques. In this context, we present the unique possibilities offered for time-resolved investigations on the attosecond timescale by the new Extreme Light Infrastructure Attosecond Light Pulse Source, which is currently under construction.

  1. Ammonia generators for GD-KAT (advanced SCR) systems; Ammoniakgeneratoren fuer GD-KAT-Systeme

    Energy Technology Data Exchange (ETDEWEB)

    Jacob, E. [MAN Nutzfahrzeuge AG, Nuernberg (Germany)

    2004-07-01

    Catalyzed thermal decomposition of aqueous solution of urea (AdBlue) or solid urea is the preferred way to generate the reducing agent ammonia, NH{sub 3}, for selective catalytic reduction (SCR) of NO{sub x} in the diesel engine exhaust gas. Various types of decomposition reactors, called ammonia generators, are possible which differ in their effectiveness to produce ammonia from urea. For reasons of simplicity, the decomposition is usually performed by atomizing AdBlue directly into the hot exhaust. However, this technique suffers from high space velocities (SV), leading to incomplete vaporization of water and only slight decomposition into NH{sub 3} and HNCO and causing a significant performance loss of the SCR catalyst. The catalyzed thermohydrolysis out of the main exhaust stream allows much decreased SV for the urea decomposition. A catalytic reactor utilizing a partial or an auxilliary (for solid urea only) stream of the exhaust gas seems particularly promising, leading to NH{sub 3} practically free from HNCO. (orig.)

  2. Advancements and challenges in generating accurate animal models of gestational diabetes mellitus

    Science.gov (United States)

    Pasek, Raymond C.

    2013-01-01

    The maintenance of glucose homeostasis during pregnancy is critical to the health and well-being of both the mother and the developing fetus. Strikingly, approximately 7% of human pregnancies are characterized by insufficient insulin production or signaling, resulting in gestational diabetes mellitus (GDM). In addition to the acute health concerns of hyperglycemia, women diagnosed with GDM during pregnancy have an increased incidence of complications during pregnancy as well as an increased risk of developing type 2 diabetes (T2D) later in life. Furthermore, children born to mothers diagnosed with GDM have increased incidence of perinatal complications, including hypoglycemia, respiratory distress syndrome, and macrosomia, as well as an increased risk of being obese or developing T2D as adults. No single environmental or genetic factor is solely responsible for the disease; instead, a variety of risk factors, including weight, ethnicity, genetics, and family history, contribute to the likelihood of developing GDM, making the generation of animal models that fully recapitulate the disease difficult. Here, we discuss and critique the various animal models that have been generated to better understand the etiology of diabetes during pregnancy and its physiological impacts on both the mother and the fetus. Strategies utilized are diverse in nature and include the use of surgical manipulation, pharmacological treatment, nutritional manipulation, and genetic approaches in a variety of animal models. Continued development of animal models of GDM is essential for understanding the consequences of this disease as well as providing insights into potential treatments and preventative measures. PMID:24085033

  3. Fitness Consequences of Advanced Ancestral Age over Three Generations in Humans.

    Directory of Open Access Journals (Sweden)

    Adam D Hayward

    Full Text Available A rapid rise in age at parenthood in contemporary societies has increased interest in reports of higher prevalence of de novo mutations and health problems in individuals with older fathers, but the fitness consequences of such age effects over several generations remain untested. Here, we use extensive pedigree data on seven pre-industrial Finnish populations to show how the ages of ancestors for up to three generations are associated with fitness traits. Individuals whose fathers, grandfathers and great-grandfathers fathered their lineage on average under age 30 were ~13% more likely to survive to adulthood than those whose ancestors fathered their lineage at over 40 years. In addition, females had a lower probability of marriage if their male ancestors were older. These findings are consistent with an increase of the number of accumulated de novo mutations with male age, suggesting that deleterious mutations acquired from recent ancestors may be a substantial burden to fitness in humans. However, possible non-mutational explanations for the observed associations are also discussed.

  4. A human factors evaluation of advanced control facilities in Korea Next Generation Reactor

    International Nuclear Information System (INIS)

    Byun, Seong Nam; Lee, Dong Hoon; Chung, Sung Hak; Kim, Dong Nam; Hwang, Sang Ho

    2001-07-01

    The objectives of this study are as follows: to evaluate the impacts of advanced MMIs on operator performance; to identify new types of human errors; to present Human Factors Engineering (HFE) issues to support the safety reviews performed by the Korea Institute for Nuclear Safety. General trends in the performance measures of cognitive task demand, mental workload, and situation awareness were analyzed. The results showed that the conventional plant was superior to KNGR on the operator performance. The results of the questionnaire revealed that WDS was the most frequently used MMI resource, followed by CPS, LDP, SC, and AS. The evaluation of operator's satisfaction showed that WDS was the most satisfactory resource, followed by LDP, SC, CPS', and AS, AS was rated as the most worst resource due to inappropriate functional organization and lack of operator's visibility. Stepwise regression analyses showed that human errors of SRO and RO were mainly dominated by the cognitive behavior of 'interpretation' with WDS, while the cognitive behavior of TO was mainly dominated by 'observation' with WDS and AS. The ten HFE issues for the KNGR MCR were presented to address important design deficiencies identified in this study. The issues should be resolved to improve safety of KNGR at least up to the level of the conventional NPPs. Verification and validation activities after implementing those resolutions should be also performed to reach optimal plant safety and other operational goals

  5. A human factors evaluation of advanced control facilities in Korea Next Generation Reactor

    Energy Technology Data Exchange (ETDEWEB)

    Byun, Seong Nam; Lee, Dong Hoon; Chung, Sung Hak; Kim, Dong Nam; Hwang, Sang Ho [Kyunghee Univ., Seoul (Korea, Republic of)

    2001-07-15

    The objectives of this study are as follows: to evaluate the impacts of advanced MMIs on operator performance; to identify new types of human errors; to present Human Factors Engineering (HFE) issues to support the safety reviews performed by the Korea Institute for Nuclear Safety. General trends in the performance measures of cognitive task demand, mental workload, and situation awareness were analyzed. The results showed that the conventional plant was superior to KNGR on the operator performance. The results of the questionnaire revealed that WDS was the most frequently used MMI resource, followed by CPS, LDP, SC, and AS. The evaluation of operator's satisfaction showed that WDS was the most satisfactory resource, followed by LDP, SC, CPS', and AS, AS was rated as the most worst resource due to inappropriate functional organization and lack of operator's visibility. Stepwise regression analyses showed that human errors of SRO and RO were mainly dominated by the cognitive behavior of 'interpretation' with WDS, while the cognitive behavior of TO was mainly dominated by 'observation' with WDS and AS. The ten HFE issues for the KNGR MCR were presented to address important design deficiencies identified in this study. The issues should be resolved to improve safety of KNGR at least up to the level of the conventional NPPs. Verification and validation activities after implementing those resolutions should be also performed to reach optimal plant safety and other operational goals.

  6. Advanced Environmentally Resistant Lithium Fluoride Mirror Coatings for the Next Generation of Broadband Space Observatories

    Science.gov (United States)

    Fleming, Brian; Quijada, Manuel A.; Hennessy, John; Egan, Arika; Del Hoyo, Javier G.

    2017-01-01

    Recent advances in the physical vapor deposition (PVD) of protective fluoride films have raised the far-ultraviolet (FUV: 912-1600 A) reflectivity of aluminum-based mirrors closer to the theoretical limit. The greatest gains, at more than 20%, have come for lithium fluoride-protected aluminum, which has the shortest wavelength cutoff of any conventional overcoat. Despite the success of the NASA FUSE mission, the use of lithium fluoride (LiF)-based optics is rare, as LiF is hygroscopic and requires handling procedures that can drive risk. With NASA now studying two large mission concepts for astronomy, Large UV-Optical-IR Surveyor (LUVOIR) and the Habitable Exoplanet Imaging Mission (HabEx), which mandate throughput down to 1000 , the development of LiF-based coatings becomes crucial. This paper discusses steps that are being taken to qualify these new enhanced LiF-protected aluminum (eLiF) mirror coatings for flight. In addition to quantifying the hygroscopic degradation, we have developed a new method of protecting eLiF with an ultrathin (10-20 A) capping layer of a nonhygroscopic material to increase durability. We report on the performance of eLiF-based optics and assess the steps that need to be taken to qualify such coatings for LUVOIR, HabEx, and other FUV-sensitive space missions.

  7. Climate Generation: Advancing Climate Action through Education, Public Engagement and Youth Leadership

    Science.gov (United States)

    Poppleton, K. L. I.

    2017-12-01

    Climate Generation: A Will Steger Legacy empowers youth, educators, decision-makers and the public to foster climate literacy and action with the goal of building a more equitable and resilient future. We have over eleven years of experience delivering high-quality K-12 education, public engagement and youth leadership programming, reaching over 75,000 people, 35,000 students and 17,000 educators since 2006. By engaging educators, youth, and the public, we believe that communities can be better positioned to build a resilient and equitable future. For this reason we strive to engage with all these sectors through innovative programming and policy initiatives. Communities are resilient when individuals are connected to each other, resources, and decision-makers. Sharing personal narratives, and highlighting locally relevant solutions are all tools that Climate Generation employs to engage the public. We do this through community wide convenings, as well as sector specific events including at breweries, art fairs, and businesses. Education is also an integral piece for sustained action on climate change. We support educators with a science-based, interdisciplinary model of climate change education that engages all learners, and fosters climate literacy and action. We develop curriculum and offer professional development, encouraging teachers to develop today's students into action-competent citizens. Finally, Climate Generation recognizes the importance of empowering high school youth as a key strategy in transitioning to a just and sustainable future for all. We believe in the inherent genius of youth and know from experience that mentorship fosters powerful youth leadership at the community level, inspiring peers, family members, and local decision-makers to take critical action on climate change solutions. In order to accelerate and implement action on climate change we must take a multi-faceted approach: we are building public will for strong climate action at

  8. Reduction of construction period by development and applying of advanced turbine generator foundation as composite structure

    International Nuclear Information System (INIS)

    Sekimoto, Hisashi; Fuyama, Hiroyuki; Kameda, Ichiro; Fukunaga, Yuuji; Umetada, Isao; Magoshi, Ryutaro

    1999-01-01

    Mitsubishi Heavy Industries developed a composite steel-concrete beam for constructing elevated horizontal beams for turbine-generator foundations. This system was used at the company's Verification Test Plant at the Takasago Machinery Works. Composite steel-concrete beams are made from U-shaped steel casings that acts as a temporarily formwork and are permanently used as major concrete beam reinforcement. Prefabricated U-shaped steel casings must be placed on top of vertical concrete columns. After steel casings are positioned and secured, concrete is filled. This technique cuts one month from construction time and simplifies required temporary work such as falsework and formwork. This paper details the results of practical research on design and construction as they relate to required strength and vibration. (author)

  9. Advanced E-O test capability for Army Next-Generation Automated Test System (NGATS)

    Science.gov (United States)

    Errea, S.; Grigor, J.; King, D. F.; Matis, G.; McHugh, S.; McKechnie, J.; Nehring, B.

    2015-05-01

    The Future E-O (FEO) program was established to develop a flexible, modular, automated test capability as part of the Next Generation Automatic Test System (NGATS) program to support the test and diagnostic needs of currently fielded U.S. Army electro-optical (E-O) devices, as well as being expandable to address the requirements of future Navy, Marine Corps and Air Force E-O systems. Santa Barbara infrared (SBIR) has designed, fabricated, and delivered three (3) prototype FEO for engineering and logistics evaluation prior to anticipated full-scale production beginning in 2016. In addition to presenting a detailed overview of the FEO system hardware design, features and testing capabilities, the integration of SBIR's EO-IR sensor and laser test software package, IRWindows 4™, into FEO to automate the test execution, data collection and analysis, archiving and reporting of results is also described.

  10. NATO Advanced Study Institute on Materials Issues for Generation IV Systems : Status, Open Questions and Challenges

    CERN Document Server

    Gorse, Dominique; Mazière, Dominique; Pontikis, Vassilis

    2008-01-01

    Global warming, shortage of low-cost oil resources and the increasing demand for energy are currently controlling the world's economic expansion while often opposing desires for sustainable and peaceful development. In this context, atomic energy satisfactorily fulfills the criteria of low carbon gas production and high overall yield. However, in the absence of industrial fast-breeders the use of nuclear fuel is not optimal, and the production of high activity waste materials is at a maximum. These are the principal reasons for the development of a new, fourth generation of nuclear reactors, minimizing the undesirable side-effects of current nuclear energy production technology while increasing yields by increasing operation temperatures and opening the way for the industrial production of hydrogen through the decomposition of water. The construction and use of such reactors is hindered by several factors, including performance limitations of known structural materials, particularly if the life of the project...

  11. A rule-based expert system for generating control displays at the Advanced Photon Source

    International Nuclear Information System (INIS)

    Coulter, K.J.

    1993-01-01

    The integration of a rule-based expert system for generating screen displays for controlling and monitoring instrumentation under the Experimental Physics and Industrial Control System (EPICS) is presented. The expert system is implemented using CLIPS, an expert system shell from the Software Technology Branch at Lyndon B. Johnson Space Center. The user selects the hardware input and output to be displayed and the expert system constructs a graphical control screen appropriate for the data. Such a system provides a method for implementing a common look and feel for displays created by several different users and reduces the amount of time required to create displays for new hardware configurations. Users are able to modify the displays as needed using the EPICS display editor tool

  12. Advanced Backstepping controller for induction generator using multi-scalar machine model for wind power purposes

    Energy Technology Data Exchange (ETDEWEB)

    Nemmour, A.L.; Khezzar, A.; Hacil, M.; Louze, L. [Laboratoire d' Electrotechnique LEC, Universite Mentouri, Constantine (Algeria); Mehazzem, F. [Groupe ESIEE, Paris Est University (France); Abdessemed, R. [Laboratoire d' Electrotechnique LEB, Universite El Hadj Lakhdar, Batna (Algeria)

    2010-10-15

    This paper presents a new non-linear control Algorithm based on the Backstepping approach for an isolated induction generator (IG) driven by a wind turbine. For this purpose and in order to reduce the complexity of the real induction machine mathematical model, the multi-scalar machine model is exploited. The machine delivers an active power to the load via a converter connected to a single capacitor on the dc-side. So, during the voltage build-up process, the necessary stator currents references to be injected by the converter are calculated from the desired active power to be sent to the load and the rotor flux magnitude. Simulation results show that the proposed control provides perfect tracking performances of the DC-bus voltage and the rotor flux magnitude to their reference trajectories. (author)

  13. Concise Review: Advances in Generating Hepatocytes from Pluripotent Stem Cells for Translational Medicine.

    Science.gov (United States)

    Szkolnicka, Dagmara; Hay, David C

    2016-06-01

    The liver is one of the major organs in the human body. Severe or prolonged exposure of the liver to different factors may cause life-threatening disease, which necessitates donor organ transplantation. While orthotopic liver transplantation can be used to effectively treat liver failure, it is an invasive procedure, which is severely limited by organ donation. Therefore, alternative sources of liver support have been proposed and studied. This includes the use of pluripotent stem cell-derived hepatocytes as a renewable source of cells for therapy. In addition to cell-based therapies, in vitro engineered liver tissue provides powerful models for human drug discovery and disease modeling. This review focuses on the generation of hepatocyte-like cells from pluripotent stem cells and their application in translational medicine. Stem Cells 2016;34:1421-1426. © 2016 The Authors Stem Cells published by Wiley Periodicals, Inc. on behalf of AlphaMed Press 2016.

  14. Recent Advances in Osmotic Energy Generation via Pressure-Retarded Osmosis (PRO: A Review

    Directory of Open Access Journals (Sweden)

    Jihye Kim

    2015-10-01

    Full Text Available Global energy consumption has been highly dependent on fossil fuels which cause severe climate change and, therefore, the exploration of new technologies to produce effective renewable energy plays an important role in the world. Pressure-retarded osmosis (PRO is one of the promising candidates to reduce the reliance on fossil fuels by harnessing energy from the salinity gradient between seawater and fresh water. In PRO, water is transported though a semi-permeable membrane from a low-concentrated feed solution to a high-concentrated draw solution. The increased volumetric water flow then runs a hydro-turbine to generate power. PRO technology has rapidly improved in recent years; however, the commercial-scale PRO plant is yet to be developed. In this context, recent developments on the PRO process are reviewed in terms of mathematical models, membrane modules, process designs, numerical works, and fouling and cleaning. In addition, the research requirements to accelerate PRO commercialization are discussed. It is expected that this article can help comprehensively understand the PRO process and thereby provide essential information to activate further research and development.

  15. Application of Neutron Measurements to Advance Semiconductor Manufacturing: Next-Generation Lithography and Nanoporous Thin Films

    Science.gov (United States)

    Lin, Eric

    2010-03-01

    As feature sizes in microelectronic devices continue to decrease to sub-32 nm dimensions, new measurement methods are needed to understand the physical phenomena used in state-of-the-art lithography methods that may limit their fabrication and probe the structure and properties of new electronics materials. Neutron (and x-ray) beams have emerged as powerful probes of new manufactured structures with characteristic length scales ranging from (1 to 100) nm in thin films and in the bulk. In particular, X-ray reflectivity (XR), neutron reflectivity (NR), small angle neutron scattering (SANS), and small angle X-ray scattering (SAXS) can be applied in novel ways to address fundamental issues important to the microelectronics industry. This talk with highlight the application of neutron and x-ray measurement methods to investigate important problems in the development of photoresist materials used in lithography and of nanoporous low-dielectric-constant materials needed for next generation integrated circuits. Specific topics include: 1) the direct measurement of the reaction-diffusion front with nanometer resolution from ideal line-edges to probe image blur and roughness from photoacid diffusion 2) identification and measurement of a ``residual swelling fraction'' during the development and 3) measurements of the pore structure of low-dielectric constant thin films. Insights from these studies can provide guidelines and opportunities for the further extension of photoresist technology into the future and the integration of new materials into integrated circuits.

  16. Parametric Analysis of a Hover Test Vehicle using Advanced Test Generation and Data Analysis

    Science.gov (United States)

    Gundy-Burlet, Karen; Schumann, Johann; Menzies, Tim; Barrett, Tony

    2009-01-01

    Large complex aerospace systems are generally validated in regions local to anticipated operating points rather than through characterization of the entire feasible operational envelope of the system. This is due to the large parameter space, and complex, highly coupled nonlinear nature of the different systems that contribute to the performance of the aerospace system. We have addressed the factors deterring such an analysis by applying a combination of technologies to the area of flight envelop assessment. We utilize n-factor (2,3) combinatorial parameter variations to limit the number of cases, but still explore important interactions in the parameter space in a systematic fashion. The data generated is automatically analyzed through a combination of unsupervised learning using a Bayesian multivariate clustering technique (AutoBayes) and supervised learning of critical parameter ranges using the machine-learning tool TAR3, a treatment learner. Covariance analysis with scatter plots and likelihood contours are used to visualize correlations between simulation parameters and simulation results, a task that requires tool support, especially for large and complex models. We present results of simulation experiments for a cold-gas-powered hover test vehicle.

  17. Carbon dioxide capture and separation techniques for advanced power generation point sources

    Energy Technology Data Exchange (ETDEWEB)

    Pennline, H.W.; Luebke, D.R.; Morsi, B.I.; Heintz, Y.J.; Jones, K.L.; Ilconich, J.B.

    2006-09-01

    The capture/separation step for carbon dioxide (CO2) from large-point sources is a critical one with respect to the technical feasibility and cost of the overall carbon sequestration scenario. For large-point sources, such as those found in power generation, the carbon dioxide capture techniques being investigated by the in-house research area of the National Energy Technology Laboratory possess the potential for improved efficiency and costs as compared to more conventional technologies. The investigated techniques can have wide applications, but the research has focused on capture/separation of carbon dioxide from flue gas (postcombustion from fossil fuel-fired combustors) and from fuel gas (precombustion, such as integrated gasification combined cycle – IGCC). With respect to fuel gas applications, novel concepts are being developed in wet scrubbing with physical absorption; chemical absorption with solid sorbents; and separation by membranes. In one concept, a wet scrubbing technique is being investigated that uses a physical solvent process to remove CO2 from fuel gas of an IGCC system at elevated temperature and pressure. The need to define an ideal solvent has led to the study of the solubility and mass transfer properties of various solvents. Fabrication techniques and mechanistic studies for hybrid membranes separating CO2 from the fuel gas produced by coal gasification are also being performed. Membranes that consist of CO2-philic silanes incorporated into an alumina support or ionic liquids encapsulated into a polymeric substrate have been investigated for permeability and selectivity. An overview of two novel techniques is presented along with a research progress status of each technology.

  18. Improvements of defects sizing reliability in steam generators tubes through advanced NDT methods

    International Nuclear Information System (INIS)

    Benoist, B.; Gondard, C.

    1994-01-01

    As the population of nuclear power plants ages, new defects are appearing in steam generator tubes (stress corrosion cracking, corrosion pitting and intergranular corrosion). Utilities are requiring additional data to characterise defects after their detection, i.e. their depth, length and orientation, in order to optimise any tube plugging decision. Eddy current (E.C.) inspection is the reference Non Destructive Testing (NDT) method for SG's tubes inspection, due the long experience gained in the field and its rapidity. But in some cases, such as circumferential crack or multi-directional crack areas, its capabilities are limited (depth evaluation). Therefore, the application of ultrasonic (U.T) inspection as a complementary method can be helpful. We present in this paper new developments in the field of rotating probes testing and data processing which improve defect detection and sizing. Present on-site E.C inspections use axial bobbin coils running along all the length of the tubes. It allows a first and fast inspection for volumetric defects (deposits, wears, bumps,..). For the areas such as tube sheets and tube support plates, rotating probes have been developed in order to improve the circumferential resolution (detection of transversal defects). To emphasize our experience, inspection on the retired SG in DAMPIERRE has been undertaken with the rotating probe. Real E.C signals of primary wall stress corrosion cracking (PWSCC) will be presented. The detection procedure is based on visual examination of E.C. images (2D surface mappings or Lissajours figures). Image processing is used for automatic detection of defect signals. A first approach consists to use image enhancement techniques such as median filter. Sobel gradient, thresholding, binary morphology, to obtain a binary image leading to the defect areas. Results will be shown on artificial defects and on the DAMPIERRE signals. (Author) 10 refs

  19. Development of ITM oxygen technology for integration in IGCC and other advanced power generation

    Energy Technology Data Exchange (ETDEWEB)

    Armstrong, Phillip A. [Air Products And Chemicals, Inc., Allentown, PA (United States)

    2015-03-31

    Ion Transport Membrane (ITM) technology is based on the oxygen-ion-conducting properties of certain mixed-metal oxide ceramic materials that can separate oxygen from an oxygen-containing gas, such as air, under a suitable driving force. The “ITM Oxygen” air separation system that results from the use of such ceramic membranes produces a hot, pure oxygen stream and a hot, pressurized, oxygen-depleted stream from which significant amounts of energy can be extracted. Accordingly, the technology integrates well with other high-temperature processes, including power generation. Air Products and Chemicals, Inc., the Recipient, in conjunction with a dozen subcontractors, developed ITM Oxygen technology under this five-phase Cooperative Agreement from the laboratory bench scale to implementation in a pilot plant capable of producing power and 100 tons per day (TPD) of purified oxygen. A commercial-scale membrane module manufacturing facility (the “CerFab”), sized to support a conceptual 2000 TPD ITM Oxygen Development Facility (ODF), was also established and operated under this Agreement. In the course of this work, the team developed prototype ceramic production processes and a robust planar ceramic membrane architecture based on a novel ceramic compound capable of high oxygen fluxes. The concept and feasibility of the technology was thoroughly established through laboratory pilot-scale operations testing commercial-scale membrane modules run under industrial operating conditions with compelling lifetime and reliability performance that supported further scale-up. Auxiliary systems, including contaminant mitigation, process controls, heat exchange, turbo-machinery, combustion, and membrane pressure vessels were extensively investigated and developed. The Recipient and subcontractors developed efficient process cycles that co-produce oxygen and power based on compact, low-cost ITMs. Process economics assessments show significant benefits relative to state

  20. Investigation of advanced nanostructured multijunction photoanodes for enhanced solar hydrogen generation via water splitting

    Science.gov (United States)

    Ishihara, Hidetaka

    As the worldwide demand for fossil-based fuel increases every day and the fossil reserve continues to be depleted, the need for alternative/renewable energy sources has gained momentum. Electric, hybrid, and hydrogen cars have been at the center of discussion lately among consumers, automobile manufacturers, and politicians, alike. The development of a fuel-cell based engine using hydrogen has been an ambitious research area over the last few decades-ever since Fujishima showed that hydrogen can be generated via the solar-energy driven photo-electrolytic splitting of water. Such solar cells are known as Photo-Electro-Chemical (PEC) solar cells. In order to commercialize this technology, various challenges associated with photo-conversion efficiency, chemical corrosion resistance, and longevity need to be overcome. In general, metal oxide semiconductors such as titanium dioxide (TiO 2, titania) are excellent candidates for PEC solar cells. Titania nanotubes have several advantages, including biocompatibility and higher chemical stability. Nevertheless, they can absorb only 5-7% of the solar spectrum which makes it difficult to achieve the higher photo-conversion efficiency required for successful commercial applications. A two-prong approach was employed to enhance photo-conversion efficiency: 1) surface modification of titania nanotubes using plasma treatment and 2) nano-capping of the titania nanotubes using titanium disilicide. The plasma surface treatment with N2 was found to improve the photo-current efficiency of titania nanotubes by 55%. Similarly, a facile, novel approach of nano-capping titania nanotubes to enhance their photocurrent response was also investigated. Electrochemically anodized titania nanotubes were capped by coating a 25 nm layer of titanium disilicide using RF magnetron sputtering technique. The optical properties of titania nanotubes were not found to change due to the capping; however, a considerable increase (40%) in the photocurrent

  1. Accelerated rogue waves generated by soliton fusion at the advanced stage of supercontinuum formation in photonic-crystal fibers.

    Science.gov (United States)

    Driben, Rodislav; Babushkin, Ihar

    2012-12-15

    Soliton fusion is a fascinating and delicate phenomenon that manifests itself in optical fibers in case of interaction between copropagating solitons with small temporal and wavelength separation. We show that the mechanism of acceleration of a trailing soliton by dispersive waves radiated from the preceding one provides necessary conditions for soliton fusion at the advanced stage of supercontinuum generation in photonic-crystal fibers. As a result of fusion, large-intensity robust light structures arise and propagate over significant distances. In the presence of small random noise the delicate condition for the effective fusion between solitons can easily be broken, making the fusion-induced giant waves a rare statistical event. Thus oblong-shaped giant accelerated waves become excellent candidates for optical rogue waves.

  2. Advancing the Oxygen Generation Assembly Design to Increase Reliability and Reduce Costs for a Future Long Duration Mission

    Science.gov (United States)

    Takada, Kevin C.; Ghariani, Ahmed E.; Van Keuren,

    2015-01-01

    The state-of-the-art Oxygen Generation Assembly (OGA) has been reliably producing breathing oxygen for the crew aboard the International Space Station (ISS) for over eight years. Lessons learned from operating the ISS OGA have led to proposing incremental improvements to advance the baseline design for use in a future long duration mission. These improvements are intended to reduce system weight, crew maintenance time and resupply mass from Earth while increasing reliability. The proposed improvements include replacing the cell stack membrane material, deleting the nitrogen purge equipment, replacing the hydrogen sensors, deleting the wastewater interface, replacing the hydrogen dome and redesigning the cell stack power supply. The development work to date will be discussed and forward work will be outlined. Additionally, a redesigned system architecture will be proposed.

  3. Selection criteria for the improvement of seed yield and its components in advances generations of lentil (lens culinaris medik)

    International Nuclear Information System (INIS)

    Ashraf, S.; Hanif, M.; Sadiq, S.; Abbas, G.; Asghar, M.J.

    2008-01-01

    Present study was conducted at Nuclear Institute for Agriculture and Biology (NIAB), Faisalabad during the years 2006 and 2007 with the objectives; to study the inheritance of seed yield and related traits in both hybridized (F6) and mutated (M6) populations of lentil and to determine the best selection criterion for the improvement of seed yield. Different genetic parameters (variances, heritabilities, genetic gains and correlations) were computed to study the inheritance pattern and interrelationships of different traits. High heritability was observed for days to flower (97.40%), plant height (90.80%), pods per plant (86.20%), hundred seed weight (83.50%) and seed yield per plant (91.80%) in F6 and for days to flower (96.9%), days to mature (91.8%), hundred seed weight (89.0%) and seed yield per plant (94.0%) in M6 generation. High heritability coupled with moderate to high genetic advance was noted for plant height (90.8%, 16.29) pods per plant (86.20%, 25.53) hundred seed weight (83.50%, 35.67) and seed yield per plant (91.80%, 35.84) in F6 generation and for days to flower (96.9%, 25.08), hundred seed weight (89.0%, 25.56) and seed yield per plant (94.0%, 37.01) in M6 generation. The traits mentioned were found to be under the control of additive genes. Seed yield had positive and significant correlation with pods per plant in M6 and with seed weight in both generations. It was concluded that seed weight and pods per plant may be used as selection criterion in both hybridized and mutated populations for the improvement of seed yield. (author)

  4. COMETS2: An advanced MATLAB toolbox for the numerical analysis of electric fields generated by transcranial direct current stimulation.

    Science.gov (United States)

    Lee, Chany; Jung, Young-Jin; Lee, Sang Jun; Im, Chang-Hwan

    2017-02-01

    Since there is no way to measure electric current generated by transcranial direct current stimulation (tDCS) inside the human head through in vivo experiments, numerical analysis based on the finite element method has been widely used to estimate the electric field inside the head. In 2013, we released a MATLAB toolbox named COMETS, which has been used by a number of groups and has helped researchers to gain insight into the electric field distribution during stimulation. The aim of this study was to develop an advanced MATLAB toolbox, named COMETS2, for the numerical analysis of the electric field generated by tDCS. COMETS2 can generate any sizes of rectangular pad electrodes on any positions on the scalp surface. To reduce the large computational burden when repeatedly testing multiple electrode locations and sizes, a new technique to decompose the global stiffness matrix was proposed. As examples of potential applications, we observed the effects of sizes and displacements of electrodes on the results of electric field analysis. The proposed mesh decomposition method significantly enhanced the overall computational efficiency. We implemented an automatic electrode modeler for the first time, and proposed a new technique to enhance the computational efficiency. In this paper, an efficient toolbox for tDCS analysis is introduced (freely available at http://www.cometstool.com). It is expected that COMETS2 will be a useful toolbox for researchers who want to benefit from the numerical analysis of electric fields generated by tDCS. Copyright © 2016. Published by Elsevier B.V.

  5. The importance of thorium in the context of the generation in advanced reactors and the IPEN's experience

    International Nuclear Information System (INIS)

    Lainetti, Paulo E.O.; Mindrisz, Ana C.; Freitas, Antonio A.

    2011-01-01

    Globally, the 80's and 90's years were characterized by a significant reduction in the rate of growth of nuclear energy. However, from the 2000's, there has been a significant change in the international arena, with the 'renaissance' of interest in nuclear energy, even in countries that had abandoned nuclear power. To answer questions like security, reducing the generation of radioactive waste, control of proliferation risks and long-term sustainability, some initiatives have been adopted by some countries. In 2000, the Department of Energy - DOE - United States created the GIF - Generation IV International Forum for Nuclear Reactors. Six reactor concepts were selected based on criteria such as: reduction of radioactive wastes, safety and cost effective to meet the increasing energy demand on a sustainable basis, being resistant to diversion of materials for nuclear weapons proliferation and safer against terrorist attacks. In this context, it becomes important to use thorium as nuclear fuel for the Generation IV Advanced Reactors, with startup scheduled for 2030. Although the thorium does not present significant commercial value nowadays, in a not too distant future it will probably be an important commodity. Unfortunately, contrarily to what is happening in most developed countries in recent years, Brazil is paying little attention to the thorium, even less than in the past, despite its large reserves. Thorium is three to four times more abundant than uranium in the Earth's crust and, although not fissile, all thorium can be used to produce 233 U, by absorption of neutrons and subsequent radioactive decay. This uranium isotope is an excellent fuel for use in almost all types of nuclear reactors. It is possible that the thorium constitutes the largest Brazilian energy reserve, supplanting much oil (despite the findings of the pre-salt) and uranium. Brazil has a long tradition in the thorium technology, from mining of monazite until the obtainment of high purity

  6. Ranger© - An Affordable, Advanced, Next-Generation, Dual-Pol, X-Band Weather Radar

    Science.gov (United States)

    Stedronsky, Richard

    2014-05-01

    The Enterprise Electronics Corporation (EEC) Ranger© system is a new generation, X-band (3 cm), Adaptive Polarization Doppler Weather Surveillance Radar that fills the gap between high-cost, high-power traditional radar systems and the passive ground station weather sensors. Developed in partnership with the University of Oklahoma Advanced Radar Research Center (ARRC), the system uses relatively low power solid-state transmitters and pulse compression technology to attain nearly the same performance capabilities of much more expensive traditional radar systems. The Ranger© also employs Adaptive Dual Polarization (ADP) techniques to allow Alternating or Simultaneous Dual Polarization capability with total control over the transmission polarization state using dual independent coherent transmitters. Ranger© has been designed using the very latest technology available in the industry and the technical and manufacturing experience gained through over four decades of successful radar system design and production at EEC. The entire Ranger© design concept emphasizes precision, stability, reliability, and value using proven solid state technology combined with the most advanced motion control system ever conceived for weather radar. Key applications include meteorology, hydrology, aviation, offshore oil/gas drilling, wind energy, and outdoor event situational awareness.

  7. Monolithic solid oxide fuel cell technology advancement for coal-based power generation. Final report, September 1989--March 1994

    Energy Technology Data Exchange (ETDEWEB)

    1994-05-01

    This project has successfully advanced the technology for MSOFCs for coal-based power generation. Major advances include: tape-calendering processing technology, leading to 3X improved performance at 1000 C; stack materials formulations and designs with sufficiently close thermal expansion match for no stack damage after repeated thermal cycling in air; electrically conducting bonding with excellent structural robustness; and sealants that form good mechanical seals for forming manifold structures. A stack testing facility was built for high-spower MSOFC stacks. Comprehensive models were developed for fuel cell performance and for analyzing structural stresses in multicell stacks and electrical resistance of various stack configurations. Mechanical and chemical compatibility properties of fuel cell components were measured; they show that the baseline Ca-, Co-doped interconnect expands and weakens in hydrogen fuel. This and the failure to develop adequate sealants were the reason for performance shortfalls in large stacks. Small (1-in. footprint) two-cell stacks were fabricated which achieved good performance (average area-specific-resistance 1.0 ohm-cm{sup 2} per cell); however, larger stacks had stress-induced structural defects causing poor performance.

  8. A next generation advanced traveler information precursor system (ATIS 2.0 precursor system) use cases report.

    Science.gov (United States)

    2017-05-01

    Advanced Traveler Information Systems (ATIS) have experienced significant growth since their initial inception in the 1990s. Technologies have continued to evolve at a rapid pace, enabling the integration of advanced solutions for traveler informatio...

  9. Discussing dying in the diaspora: attitudes towards advance care planning among first generation Dutch and Italian migrants in rural Australia.

    Science.gov (United States)

    Sinclair, Craig; Smith, Jessica; Toussaint, Yann; Auret, Kirsten

    2014-01-01

    Western cultural practices and values have largely shaped advance care planning (ACP) policies across the world. Low uptake of ACP among ethnic minority groups in Western countries has been interpreted with reference to cultural differences. This paper adopts a life-history approach to explore attitudes towards ACP among older, first-generation Dutch-Australian and Italian-Australian migrants. Thirty people participated in extended ethnographic interviews (N = 17) and group discussions (N = 13) during 2012. Transcripts were thematically analyzed and interpreted using a Foucauldian perspective on knowledge and power. Migration experiences, ongoing contact with the native country and participation in migrant community support networks influenced attitudes towards ACP. Dutch participants framed ACP discussions with reference to euthanasia, and adopted a more individualist approach to medical decision-making. Italian participants often spoke of familial roles and emphasized a family-based decision making style. The importance of migrant identity has been neglected in previous discussions of cultural factors influencing ACP uptake among ethnic minority groups. The unique migration experience should be considered alongside culturally appropriate approaches to decision-making, in order to ensure equitable access to ACP among migrant groups. Copyright © 2013 Elsevier Ltd. All rights reserved.

  10. Beliefs in advance care planning among Chinese Americans: Similarities and differences between the younger and older generations

    Directory of Open Access Journals (Sweden)

    Mei Ching Lee

    2017-10-01

    Full Text Available The purpose of this research is to explore behavioral, normative, and control beliefs in the discussion of advance care planning (ACP among older and younger Chinese Americans. Ethnic minority groups have been identified as less engaged in ACP and this represents an ethnic and cultural gap. Older Chinese American adults often have different beliefs and values compared to the younger generation who are more acculturated to American mainstream culture. These differences may hinder the discussion of ACP with Chinese older adults. A qualitative design was used. The Theory of Planned Behavior guided the development of the interview guide. We recruited 60 Chinese Americans. Prior experience was identified as a theme that influenced attitudes about ACP. We found that older and younger Chinese participants had different beliefs in the norm and control related to ACP discussions, but not in the belief of attitudes about ACP discussions. Both younger and older Chinese American participants believed that ACP was important and necessary. Participants in both clusters expressed that they were ready and willing to engage in ACP discussions with their family members but hesitant to initiate these discussions. The reluctance in discussing ACP with Chinese older adults may be related to the expectations and obligations of Xiao (filial piety in Chinese culture. This study describes the similarities and differences of beliefs in ACP between older and younger Chinese Americans. We identified barriers and facilitators in behavioral, normative, and control beliefs that can be used to promote ACP for Chinese Americans.

  11. Design of the Next Generation Nuclear Plant Graphite Creep Experiments for Irradiation in the Advanced Test Reactor

    International Nuclear Information System (INIS)

    Grover, S. Blaine

    2009-01-01

    The United States Department of Energy's Next Generation Nuclear Plant (NGNP) Program will be irradiating six gas reactor graphite creep experiments in the Advanced Test Reactor (ATR) located at the Idaho National Laboratory (INL). The ATR has a long history of irradiation testing in support of reactor development and the INL has been designated as the new United States Department of Energy's lead laboratory for nuclear energy development. The ATR is one of the world's premiere test reactors for performing long term, high flux, and/or large volume irradiation test programs. These graphite irradiations are being accomplished to support development of the next generation reactors in the United States. The graphite experiments will be irradiated over the next six to eight years to support development of a graphite irradiation performance data base on the new nuclear grade graphites now available for use in high temperature gas reactors. The goals of the irradiation experiments are to obtain irradiation performance data at different temperatures and loading conditions to support design of the Next Generation Nuclear Plant Very High Temperature Gas Reactor, as well as other future gas reactors. The experiments will each consist of a single capsule that will contain seven separate stacks of graphite specimens. Six of the specimen stacks will have half of their graphite specimens under a compressive load, while the other half of the specimens will not be subjected to a compressive load during irradiation. The six stacks will be organized into pairs with a different compressive load being applied to the top half of each pair of specimen stacks. The seventh stack will not have a compressive load on the graphite specimens during irradiation. The specimens will be irradiated in an inert sweep gas atmosphere with on-line temperature and compressive load monitoring and control. There will also be the capability of sampling the sweep gas effluent to determine if any oxidation or

  12. Effectiveness of third-generation chemotherapy on the survival of patients with advanced non-small cell lung cancer in Norway

    DEFF Research Database (Denmark)

    von Plessen, C; Strand, T-E; Wentzel-Larsen, T

    2008-01-01

    BACKGROUND: To investigate whether the introduction of modern third-generation chemotherapy was associated with survival benefits in a national population of patients with advanced non-small cell lung cancer (ANSCLC) and to explore geographical and temporary variations in the utilisation of chemo...

  13. Inland treatment of the brine generated from reverse osmosis advanced membrane wastewater treatment plant using epuvalisation system.

    Science.gov (United States)

    Qurie, Mohannad; Abbadi, Jehad; Scrano, Laura; Mecca, Gennaro; Bufo, Sabino A; Khamis, Mustafa; Karaman, Rafik

    2013-07-03

    The reverse osmosis (RO) brine generated from the Al-Quds University wastewater treatment plant was treated using an epuvalisation system. The advanced integrated wastewater treatment plant included an activated sludge unit, two consecutive ultrafiltration (UF) membrane filters (20 kD and 100 kD cutoffs) followed by an activated carbon filter and a reverse osmosis membrane. The epuvalisation system consisted of salt tolerant plants grown in hydroponic channels under continuous water flowing in a closed loop system, and placed in a greenhouse at Al-Quds University. Sweet basil (Ocimum basilicum) plants were selected, and underwent two consecutive hydroponic flowing stages using different brine-concentrations: an adaptation stage, in which a 1:1 mixture of brine and fresh water was used; followed by a functioning stage, with 100% brine. A control treatment using fresh water was included as well. The experiment started in April and ended in June (2012). At the end of the experiment, analysis of the effluent brine showed a remarkable decrease of electroconductivity (EC), PO43-, chemical oxygen demand (COD) and K+ with a reduction of 60%, 74%, 70%, and 60%, respectively, as compared to the influent. The effluent of the control treatment showed 50%, 63%, 46%, and 90% reduction for the same parameters as compared to the influent. Plant growth parameters (plant height, fresh and dry weight) showed no significant difference between fresh water and brine treatments. Obtained results suggest that the epuvalisation system is a promising technique for inland brine treatment with added benefits. The increasing of channel number or closed loop time is estimated for enhancing the treatment process and increasing the nutrient uptake. Nevertheless, the epuvalisation technique is considered to be simple, efficient and low cost for inland RO brine treatment.

  14. Inland Treatment of the Brine Generated from Reverse Osmosis Advanced Membrane Wastewater Treatment Plant Using Epuvalisation System

    Directory of Open Access Journals (Sweden)

    Mohannad Qurie

    2013-07-01

    Full Text Available The reverse osmosis (RO brine generated from the Al-Quds University wastewater treatment plant was treated using an epuvalisation system. The advanced integrated wastewater treatment plant included an activated sludge unit, two consecutive ultrafiltration (UF membrane filters (20 kD and 100 kD cutoffs followed by an activated carbon filter and a reverse osmosis membrane. The epuvalisation system consisted of salt tolerant plants grown in hydroponic channels under continuous water flowing in a closed loop system, and placed in a greenhouse at Al-Quds University. Sweet basil (Ocimum basilicum plants were selected, and underwent two consecutive hydroponic flowing stages using different brine-concentrations: an adaptation stage, in which a 1:1 mixture of brine and fresh water was used; followed by a functioning stage, with 100% brine. A control treatment using fresh water was included as well. The experiment started in April and ended in June (2012. At the end of the experiment, analysis of the effluent brine showed a remarkable decrease of electroconductivity (EC, PO43−, chemical oxygen demand (COD and K+ with a reduction of 60%, 74%, 70%, and 60%, respectively, as compared to the influent. The effluent of the control treatment showed 50%, 63%, 46%, and 90% reduction for the same parameters as compared to the influent. Plant growth parameters (plant height, fresh and dry weight showed no significant difference between fresh water and brine treatments. Obtained results suggest that the epuvalisation system is a promising technique for inland brine treatment with added benefits. The increasing of channel number or closed loop time is estimated for enhancing the treatment process and increasing the nutrient uptake. Nevertheless, the epuvalisation technique is considered to be simple, efficient and low cost for inland RO brine treatment.

  15. Inland Treatment of the Brine Generated from Reverse Osmosis Advanced Membrane Wastewater Treatment Plant Using Epuvalisation System

    Science.gov (United States)

    Qurie, Mohannad; Abbadi, Jehad; Scrano, Laura; Mecca, Gennaro; Bufo, Sabino A.; Khamis, Mustafa; Karaman, Rafik

    2013-01-01

    The reverse osmosis (RO) brine generated from the Al-Quds University wastewater treatment plant was treated using an epuvalisation system. The advanced integrated wastewater treatment plant included an activated sludge unit, two consecutive ultrafiltration (UF) membrane filters (20 kD and 100 kD cutoffs) followed by an activated carbon filter and a reverse osmosis membrane. The epuvalisation system consisted of salt tolerant plants grown in hydroponic channels under continuous water flowing in a closed loop system, and placed in a greenhouse at Al-Quds University. Sweet basil (Ocimum basilicum) plants were selected, and underwent two consecutive hydroponic flowing stages using different brine-concentrations: an adaptation stage, in which a 1:1 mixture of brine and fresh water was used; followed by a functioning stage, with 100% brine. A control treatment using fresh water was included as well. The experiment started in April and ended in June (2012). At the end of the experiment, analysis of the effluent brine showed a remarkable decrease of electroconductivity (EC), PO43−, chemical oxygen demand (COD) and K+ with a reduction of 60%, 74%, 70%, and 60%, respectively, as compared to the influent. The effluent of the control treatment showed 50%, 63%, 46%, and 90% reduction for the same parameters as compared to the influent. Plant growth parameters (plant height, fresh and dry weight) showed no significant difference between fresh water and brine treatments. Obtained results suggest that the epuvalisation system is a promising technique for inland brine treatment with added benefits. The increasing of channel number or closed loop time is estimated for enhancing the treatment process and increasing the nutrient uptake. Nevertheless, the epuvalisation technique is considered to be simple, efficient and low cost for inland RO brine treatment. PMID:23823802

  16. Alternative Green Technology for Power Generation Using Waste-Heat Energy And Advanced Thermoelectric Materials, Phase I

    Data.gov (United States)

    National Aeronautics and Space Administration — NASA is interested in advancing green technology research for achieving sustainable and environmentally friendly energy sources for both terrestrial and space...

  17. Advanced FeCrAl ODS steels for high-temperature structural applications in energy generation systems

    Directory of Open Access Journals (Sweden)

    Pimentel, G.

    2012-08-01

    Full Text Available Technologies and means for developing biomass plant with higher energy conversion efficiencies are essential in order to implement the commitment to renewable biomass energy generation. Advanced, indirect Combined Cycle Gas Turbine (CCGT systems offer overall biomass energy conversion efficiencies of 45 % and above, compared with the 35 % efficiency of conventional biomass steam plant. However to attain this efficiency in CCGT operation it will be necessary to develop a heat exchanger capable of gas operating temperatures and pressures of around 1100 °C and 15-30 bar, respectively, for entry heating the gas turbine working fluid. ODS ferritic steels is the kind of advance material to deal with this challenge, however work to optimize the coarse grain microstructure to improve creep hoop strength needs to be done. In this sense, this paper reports the recrystallisation behaviour of PM 2000 oxide dispersion strengthened ferritic alloy which was cold deformed after hot-rolling and extrusion. The results can be interpreted if it is assumed that anything which makes the microstructure heterogeneous, stimulates recrystallisation. In this sense, larger strain gradients lead to more refined and more isotropic grain structures. The combination of these results with finite element modeling are used to interpret the role of residual shear stresses on the development of recrystallized grain structure.

    Las tecnologías y medios para desarrollar plantas de biomasa con alta eficiencia en la conversión de energía son esenciales para asentar la biomasa como una fuente de energía renovable. Los sistemas de turbinas de gas de ciclo combinado (CCGT permiten elevar la eficiencia de las plantas de biomasa del 35 % actual al 45 %. Sin embargo, para conseguir estos niveles de eficiencia en la conversión de energía, el intercambiador de calor de la caldera debe trabajar en condiciones extremas de temperatura (por encima de 1100 °C y presión (en torno a 15

  18. Next Generation Advanced Binder Chemistries for High Performance, Environmentally DurableThermal Control Material Systems, Phase II

    Data.gov (United States)

    National Aeronautics and Space Administration — This innovative SBIR Phase II proposal will develop next generation products for Thermal Control Material Systems (TCMS) an adhesives based on the next generation...

  19. Microstructural Evolution and Creep-Rupture Behavior of Fusion Welds Involving Alloys for Advanced Ultrasupercritical Power Generation

    Science.gov (United States)

    Bechetti, Daniel H., Jr.

    Projections for large increases in the global demand for electric power produced by the burning of fossil fuels, in combination with growing environmental concerns surrounding these fuel sources, have sparked initiatives in the United States, Europe, and Asia aimed at developing a new generation of coal fired power plant, termed Advanced Ultrasupercritical (A-USC). These plants are slated to operate at higher steam temperatures and pressures than current generation plants, and in so doing will offer increased process cycle efficiency and reduced greenhouse gas emissions. Several gamma' precipitation strengthened Ni-based superalloys have been identified as candidates for the hottest sections of these plants, but the microstructural instability and poor creep behavior (compared to wrought products) of fusion welds involving these alloys present significant hurdles to their implementation and a gap in knowledge that must be addressed. In this work, creep testing and in-depth microstructural characterization have been used to provide insight into the long-term performance of these alloys. First, an investigation of the weld metal microstructural evolution as it relates to creep strength reductions in A-USC alloys INCONELRTM 740, NIMONICRTM 263 (INCONEL and NIMONIC are registered trademarks of Special Metals Corporation), and HaynesRTM 282RTM (Haynes and 282 are registered trademarks of Haynes International) was performed. gamma'-precipitate free zones were identified in two of these three alloys, and their development was linked to the evolution of phases that precipitate at the expense of gamma'. Alloy 282 was shown to avoid precipitate free zone formation because the precipitates that form during long term aging in this alloy are poor in the gamma'-forming elements. Next, the microstructural evolution of INCONELRTM 740H (a compositional variant of alloy 740) during creep was investigated. Gleeble-based interrupted creep and creep-rupture testing was used to

  20. Temperature measurements in steam generator tube plates of the advanced PWR (FDR) on the NS OTTO HAHN

    International Nuclear Information System (INIS)

    Klaeke, R.D.

    1980-01-01

    During inspection for surface cracks at the steam generator tube sheets on the feed water inlet sides in several scaling welds small cracks were found. Thermotensions are in view for their origination. To clear up the temperature conditions on the feed water inlets in the areas of the tube sheets a temperature measuring program was performed. The results showed that over a large power range during the steam generation on the feed water inlet side of the steam generator permanently temperature fluctuations took place. (orig.) [de

  1. The DOE Next-Generation Drivetrain for Wind Turbine Applications: Gearbox, Generator, and Advanced Si/SiC Hybrid Inverter System: Preprint

    Energy Technology Data Exchange (ETDEWEB)

    Erdman, William; Keller, Jonathan

    2016-08-01

    This paper reports on the design and testing results from the U.S. Department of Energy Next-Generation Wind Turbine Drivetrain Project. The drivetrain design reduces the cost of energy by increasing energy capture through drivetrain efficiency improvements; by reducing operation and maintenance costs through reducing gearbox failures; and by lowering capital costs through weight reduction and a series of mechanical and electronic innovations. The paper provides an overview of the drivetrain gearbox and generator and provides a deeper look into the power converter system. The power converter has a number of innovations including the use of hybrid silicon (Si)/silicon carbide (SiC) isolated baseplate switching modules. Switching energies are compared between SiC and Si PIN diodes. The efficiency improvement by use of the SiC diode in a three-level converter is also described. Finally, a brief discussion covering utility interconnect requirements for turbines is provided with a particular focus on utility events that lead to high transient torque loads on drivetrain mechanical elements.

  2. Development of Next Generation Energy Audit Protocols for the Rapid and Advanced Analysis of Building Energy Use

    Science.gov (United States)

    Hartley, Christopher Ahlvin

    Current building energy auditing techniques are outdated and lack targeted, actionable information. These analyses only use one year's worth of monthly electricity and gas bills to define energy conservation and efficiency measures. These limited data sets cannot provide robust, directed energy reduction recommendations. The need is apparent for an overhaul of existing energy audit protocols to utilize all data that is available from the building's utility provider, installed energy management system (EMS), and sub-metering devices. This thesis analyzed the current state-of-the-art in energy audits, generated a next generation energy audit protocol, and conducted both audits types on four case study buildings to find out what additional information can be obtained from additional data sources and increased data gathering resolutions. Energy data from each case study building were collected using a variety of means including utility meters, whole building energy meters, EMS systems, and sub-metering devices. In addition to conducting an energy analysis for each case study building using the current and next generation energy audit protocols, two building energy models were created using the programs eQuest and EnergyPlus. The current and next generation energy audit protocol results were compared to one another upon completion. The results show that using the current audit protocols, only variations in season are apparent. Results from the developed next generation energy audit protocols show that in addition to seasonal variations, building heating, ventilation and air conditioning (HVAC) schedules, occupancy schedules, baseline and peak energy demand levels, and malfunctioning equipment can be found. This new protocol may also be used to quickly generate accurate building models because of the increased resolution that yields scheduling information. The developed next generation energy auditing protocol is scalable and can work for many building types across the

  3. Final Technical Report for GO15056 Millennium Cell: Development of an Advanced Chemical Hydrogen Storage and Generation System

    Energy Technology Data Exchange (ETDEWEB)

    Moreno, Oscar [Millennium Cell Inc., Eatontown, NJ (United States)

    2017-02-22

    The objectives of this project are to increase system storage capacity by improving hydrogen generation from concentrated sodium borohydride, with emphasis on reactor and system engineering; to complete a conceptual system design based on sodium borohydride that will include key technology improvements to enable a hydrogen fuel system that will meet the systembased storage capacity of 1.2 kWh/L (36 g H2/L) and 1.5 kWh/kg (45 g H2/kg), by the end of FY 2007; and to utilize engineering expertise to guide Center research in both off-board chemical hydride regeneration and on-board hydrogen generation systems.

  4. Modelling of advanced three-ion ICRF heating and fast ion generation scheme for tokamaks and stellarators

    Science.gov (United States)

    Faustin, J. M.; Graves, J. P.; Cooper, W. A.; Lanthaler, S.; Villard, L.; Pfefferlé, D.; Geiger, J.; Kazakov, Ye O.; Van Eester, D.

    2017-08-01

    Absorption of ion-cyclotron range of frequencies waves at the fundamental resonance is an efficient source of plasma heating and fast ion generation in tokamaks and stellarators. This heating method is planned to be exploited as a fast ion source in the Wendelstein 7-X stellarator. The work presented here assesses the possibility of using the newly developed three-ion species scheme (Kazakov et al (2015) Nucl. Fusion 55 032001) in tokamak and stellarator plasmas, which could offer the capability of generating more energetic ions than the traditional minority heating scheme with moderate input power. Using the SCENIC code, it is found that fast ions in the MeV range of energy can be produced in JET-like plasmas. The RF-induced particle pinch is seen to strongly impact the fast ion pressure profile in particular. Our results show that in typical high-density W7-X plasmas, the three-ion species scheme generates more energetic ions than the more traditional minority heating scheme, which makes three-ion scenario promising for fast-ion confinement studies in W7-X.

  5. Advanced power generation systems for the 21st Century: Market survey and recommendations for a design philosophy

    Energy Technology Data Exchange (ETDEWEB)

    Andriulli, J.B.; Gates, A.E.; Haynes, H.D.; Klett, L.B.; Matthews, S.N.; Nawrocki, E.A.; Otaduy, P.J.; Scudiere, M.B.; Theiss, T.J.; Thomas, J.F.; Tolbert, L.M.; Yauss, M.L.; Voltz, C.A.

    1999-11-01

    The purpose of this report is to document the results of a study designed to enhance the performance of future military generator sets (gen-sets) in the medium power range. The study includes a market survey of the state of the art in several key component areas and recommendations comprising a design philosophy for future military gen-sets. The market survey revealed that the commercial market is in a state of flux, but it is currently or will soon be capable of providing the technologies recommended here in a cost-effective manner. The recommendations, if implemented, should result in future power generation systems that are much more functional than today's gen-sets. The number of differing units necessary (both family sizes and frequency modes) to cover the medium power range would be decreased significantly, while the weight and volume of each unit would decrease, improving the transportability of the power source. Improved fuel economy and overall performance would result from more effective utilization of the prime mover in the generator. The units would allow for more flexibility and control, improved reliability, and more effective power management in the field.

  6. Superconducting Multi-Cell Deflecting Cavity for Short-Pulse X-Ray Generation at the Advanced Photon Source

    Energy Technology Data Exchange (ETDEWEB)

    G.J. Waldschmidt, L.H. Morrison, R. Nassiri, R.A. Rimmer, K. Tian, H. Wang

    2009-05-01

    A superconducting multi-cell cavity for the production of short x-ray pulses at the Advanced Photon Source (APS) has been explored as an alternative to a single-cell cavity design in order to improve the packing factor and potentially reduce the number of high-power RF systems and low-level RF controls required. The cavity will operate at 2815 MHz in the APS storage ring and will require heavy damping of parasitic modes to maintain stable beam operation. Novel on-cell dampers, attached directly to the cavity body, have been utilized by taking advantage of the magnetic field null on the equatorial plane in order to enhance damping. Design issues and simulation results will be discussed.

  7. Ion acceleration and D-D nuclear fusion in laser-generated plasma from advanced deuterated polyethylene.

    Science.gov (United States)

    Torrisi, Lorenzo

    2014-10-23

    Deuterated polyethylene targets have been irradiated by means of a 1016 W/cm2 laser using 600 J pulse energy, 1315 nm wavelength, 300 ps pulse duration and 70 micron spot diameter. The plasma parameters were measured using on-line diagnostics based on ion collectors, SiC detectors and plastic scintillators, all employed in time-of-flight configuration. In addition, a Thomson parabola spectrometer, an X-ray streak camera, and calibrated neutron dosimeter bubble detectors were employed. Characteristic protons and neutrons at maximum energies of 3.0 MeV and 2.45 MeV, respectively, were detected, confirming that energy spectra of reaction products coming from deuterium-deuterium nuclear fusion occur. In thick advanced targets a fusion rate of the order of 2 × 108 fusions per laser shot was calculated.

  8. Ion Acceleration and D-D Nuclear Fusion in Laser-Generated Plasma from Advanced Deuterated Polyethylene

    Directory of Open Access Journals (Sweden)

    Lorenzo Torrisi

    2014-10-01

    Full Text Available Deuterated polyethylene targets have been irradiated by means of a 1016 W/cm2 laser using 600 J pulse energy, 1315 nm wavelength, 300 ps pulse duration and 70 micron spot diameter. The plasma parameters were measured using on-line diagnostics based on ion collectors, SiC detectors and plastic scintillators, all employed in time-of-flight configuration. In addition, a Thomson parabola spectrometer, an X-ray streak camera, and calibrated neutron dosimeter bubble detectors were employed. Characteristic protons and neutrons at maximum energies of 3.0 MeV and 2.45 MeV, respectively, were detected, confirming that energy spectra of reaction products coming from deuterium-deuterium nuclear fusion occur. In thick advanced targets a fusion rate of the order of 2 × 108 fusions per laser shot was calculated.

  9. Advanced glycation end products induce human corneal epithelial cells apoptosis through generation of reactive oxygen species and activation of JNK and p38 MAPK pathways.

    Directory of Open Access Journals (Sweden)

    Long Shi

    Full Text Available Advanced Glycation End Products (AGEs has been implicated in the progression of diabetic keratopathy. However, details regarding their function are not well understood. In the present study, we investigated the effects of intracellular reactive oxygen species (ROS and JNK, p38 MAPK on AGE-modified bovine serum albumin (BSA induced Human telomerase-immortalized corneal epithelial cells (HUCLs apoptosis. We found that AGE-BSA induced HUCLs apoptosis and increased Bax protein expression, decreased Bcl-2 protein expression. AGE-BSA also induced the expression of receptor for advanced glycation end product (RAGE. AGE-BSA-RAGE interaction induced intracellular ROS generation through activated NADPH oxidase and increased the phosphorylation of p47phox. AGE-BSA induced HUCLs apoptosis was inhibited by pretreatment with NADPH oxidase inhibitors, ROS quencher N-acetylcysteine (NAC or neutralizing anti-RAGE antibodies. We also found that AGE-BSA induced JNK and p38 MAPK phosphorylation. JNK and p38 MAPK inhibitor effectively blocked AGE-BSA-induced HUCLs apoptosis. In addition, NAC completely blocked phosphorylation of JNK and p38 MAPK induced by AGE-BSA. Our results indicate that AGE-BSA induced HUCLs apoptosis through generation of intracellular ROS and activation of JNK and p38 MAPK pathways.

  10. Next generation bioelectronics: Advances in fabrication coupled with clever chemistries enable the effective integration of biomaterials and organic conductors

    Directory of Open Access Journals (Sweden)

    Paul J. Molino

    2015-01-01

    Full Text Available Organic bioelectronics is making an enormous impact in the field of tissue engineering, providing not just biocompatible, but biofunctional conducting material platforms. For their true potential to be reached, it is critical to integrate organic conductors with other biopolymers in a targeted manner, allowing the development of devices and scaffold architectures capable of delivering a number of physical, chemical, and electrical stimuli. Herein, we provide an overview of the methods currently being employed to tailor organic conductors for bioapplications, with a focus on the development of fabrication techniques vital to the development of the next generation of intelligent bionic devices.

  11. The use of advanced scale conditioning agents for maintenance of the secondary side of nuclear plant steam generators

    International Nuclear Information System (INIS)

    Battaglia, P.J.; Rogosky, D.L.

    2006-01-01

    Maintaining the secondary side of steam generators within a pressurized water reactor (PWR) free of deposited corrosion products and corrosion-inducing contaminants is key to ensuring their long-term operation. New cleaning processes have become available to aid nuclear plant personnel in optimizing secondary side maintenance strategies. These strategies include both maintaining nuclear steam generators corrosion free while maintaining full power operation. The conference presentation will discuss ASCA use and the major field experience acquired in the last several years in the United States and in Japan. Hokkaido Electric, Dominion Engineering, Inc. and Westinghouse cosponsored the development of ASCAs for use in the Nuclear Utility industry, and all three are active in field use programs. Westinghouse owns the worldwide rights for ASCA implementation except in Japan where MHI and NEL have been granted licenses to apply ASCAs. Dominion Engineering Inc., owns the ASCA patents and performs the laboratory qualification testing associated with the ASCA programs, and Hokkaido Electric are joint patent holders for ASCAs and have been implementing their use at the Tomari plants for cleaning and thermal hydraulic performance enhancements. The specific experience discussed in the presentation will include: 1. Full Bundle Maintenance ASCAs at Vogtle Units 2 and 2 and Wolf Creek (USA). 2. Top of the Tubesheet ASCAs with high pressure sludge lancing at Wolf Creek and UEC at Vogtle Units 1 and 2 (USA). 3. Thermal Hydraulic Recovery and Maintenance ASCAs at the Hokkaido Electric Tomari Units 1 and 2 (Japan). (author)

  12. Advanced Propulsion Power Distribution System for Next Generation Electric/Hybrid Vehicle. Phase 1; Preliminary System Studies

    Science.gov (United States)

    Bose, Bimal K.; Kim, Min-Huei

    1995-01-01

    The report essentially summarizes the work performed in order to satisfy the above project objective. In the beginning, different energy storage devices, such as battery, flywheel and ultra capacitor are reviewed and compared, establishing the superiority of the battery. Then, the possible power sources, such as IC engine, diesel engine, gas turbine and fuel cell are reviewed and compared, and the superiority of IC engine has been established. Different types of machines for drive motor/engine generator, such as induction machine, PM synchronous machine and switched reluctance machine are compared, and the induction machine is established as the superior candidate. Similar discussion was made for power converters and devices. The Insulated Gate Bipolar Transistor (IGBT) appears to be the most superior device although Mercury Cadmium Telluride (MCT) shows future promise. Different types of candidate distribution systems with the possible combinations of power and energy sources have been discussed and the most viable system consisting of battery, IC engine and induction machine has been identified. Then, HFAC system has been compared with the DC system establishing the superiority of the former. The detailed component sizing calculations of HFAC and DC systems reinforce the superiority of the former. A preliminary control strategy has been developed for the candidate HFAC system. Finally, modeling and simulation study have been made to validate the system performance. The study in the report demonstrates the superiority of HFAC distribution system for next generation electric/hybrid vehicle.

  13. Inducing pluripotency in vitro: recent advances and highlights in induced pluripotent stem cells generation and pluripotency reprogramming.

    Science.gov (United States)

    Rony, I K; Baten, A; Bloomfield, J A; Islam, M E; Billah, M M; Islam, K D

    2015-04-01

    Induced pluripotent stem cells (iPSCs) are considered patient-specific counterparts of embryonic stem cells as they originate from somatic cells after forced expression of pluripotency reprogramming factors Oct4, Sox2, Klf4 and c-Myc. iPSCs offer unprecedented opportunity for personalized cell therapies in regenerative medicine. In recent years, iPSC technology has undergone substantial improvement to overcome slow and inefficient reprogramming protocols, and to ensure clinical-grade iPSCs and their functional derivatives. Recent developments in iPSC technology include better reprogramming methods employing novel delivery systems such as non-integrating viral and non-viral vectors, and characterization of alternative reprogramming factors. Concurrently, small chemical molecules (inhibitors of specific signalling or epigenetic regulators) have become crucial to iPSC reprogramming; they have the ability to replace putative reprogramming factors and boost reprogramming processes. Moreover, common dietary supplements, such as vitamin C and antioxidants, when introduced into reprogramming media, have been found to improve genomic and epigenomic profiles of iPSCs. In this article, we review the most recent advances in the iPSC field and potent application of iPSCs, in terms of cell therapy and tissue engineering. © 2015 John Wiley & Sons Ltd.

  14. Fruit cuticle lipid composition and fruit post-harvest water loss in an advanced backcross generation of pepper (Capsicum sp.)

    KAUST Repository

    Parsons, Eugene P.

    2012-03-05

    To understand the role of fruit cuticle lipid composition in fruit water loss, an advanced backcross population, the BC2F2, was created between the Capsicum annuum (PI1154) and the Capsicum chinense (USDA162), which have high and low post-harvest water loss rates, respectively. Besides dramatic differences in fruit water loss, preliminary studies also revealed that these parents exhibited significant differences in both the amount and composition of their fruit cuticle. Cuticle analysis of the BC2F2 fruit revealed that although water loss rate was not strongly associated with the total surface wax amount, there were significant correlations between water loss rate and cuticle composition. We found a positive correlation between water loss rate and the amount of total triterpenoid plus sterol compounds, and negative correlations between water loss and the alkane to triterpenoid plus sterol ratio. We also report negative correlations between water loss rate and the proportion of both alkanes and aliphatics to total surface wax amount. For the first time, we report significant correlations between water loss and cutin monomer composition. We found positive associations of water loss rate with the total cutin, total C16 monomers and 16-dihydroxy hexadecanoic acid. Our results support the hypothesis that simple straight-chain aliphatic cuticle constituents form more impermeable cuticular barriers than more complex isoprenoid-based compounds. These results shed new light on the biochemical basis for cuticle involvement in fruit water loss. © 2012 Physiologia Plantarum.

  15. SEMICONDUCTOR INTEGRATED CIRCUITS: An advanced monolithic digitalized random carrier frequency spread-spectrum clock generator for EMI suppression

    Science.gov (United States)

    Haiyan, Guo; Zao, Chen; Bo, Zhang; Zhaoji, Li

    2010-06-01

    A novel monolithic digitalized random carrier frequency modulation spread-spectrum clock generator (RCF-SSCG) is proposed. In this design, the output frequency of the proposed RCF-SSCG changes with the intensity of the capacitive charge and discharge current. Its analytical model is induced and the effect of the modulation parameters on the spread spectrum is numerically simulated and discussed. Compared with other works, this design has the advantages of small size, low power consumption and good robustness. The circuit has been fabricated in a 0.5 μm CMOS process and applied to a class D amplifier in which the proposed RCF-SSCG occupies an area of 0.112 mm2 and consumes 9 mW. The experimental results confirm the theoretical analyses.

  16. Nano-design of quantum dot-based photocatalysts for hydrogen generation using advanced surface molecular chemistry

    KAUST Repository

    Yu, Weili

    2015-01-01

    Efficient photocatalytic hydrogen generation in a suspension system requires a sophisticated nano-device that combines a photon absorber with effective redox catalysts. This study demonstrates an innovative molecular linking strategy for fabricating photocatalytic materials that allow effective charge separation of excited carriers, followed by efficient hydrogen evolution. The method for the sequential replacement of ligands with appropriate molecules developed in this study tethers both quantum dots (QDs), as photosensitizers, and metal nanoparticles, as hydrogen evolution catalysts, to TiO2 surfaces in a controlled manner at the nano-level. Combining hydrophobic and hydrophilic interactions on the surface, CdSe-ZnS core-shell QDs and an Au-Pt alloy were attached to TiO2 without overlapping during the synthesis. The resultant nano-photocatalysts achieved substantially high-performance visible-light-driven photocatalysis for hydrogen evolution. All syntheses were conducted at room temperature and in ambient air, providing a promising route for fabricating visible-light-responsive photocatalysts.

  17. Commissioning and early experience with a new-generation low-energy linear accelerator with advanced delivery and imaging functionalities

    Directory of Open Access Journals (Sweden)

    Fogliata Antonella

    2011-09-01

    Full Text Available Abstract Background A new-generation low-energy linear accelerator (UNIQUE was introduced in the clinical arena during 2009 by Varian Medical Systems. The world's first UNIQUE was installed at Oncology Institute of Southern Switzerland and put into clinical operation in June 2010. The aim of the present contribution was to report experience about its commissioning and first year results from clinical operation. Methods Commissioning data, beam characteristics and the modeling into the treatment planning system were summarized. Imaging system of UNIQUE included a 2D-2D matching capability and tests were performed to identify system repositioning capability. Finally, since the system is capable of delivering volumetric modulated arc therapy with RapidArc, a summary of the tests performed for such modality to assess its performance in preclinical settings and during clinical usage was included. Results Isocenter virtual diameter was measured as less than 0.2 mm. Observed accuracy of isocenter determination and repositioning for 2D-2D matching procedures in image guidance was Conclusions The results of the commissioning tests and of the first period of clinical operation, resulted meeting specifications and having good margins respect to tolerances. UNIQUE was put into operation for all delivery techniques; in particular, as shown by the pre-treatment quality assurance results, it enabled accurate and safe delivery of RapidArc plans.

  18. Advances in the analysis of complex food matrices: Species identification in surimi-based products using Next Generation Sequencing technologies

    Science.gov (United States)

    Sotelo, Carmen G.

    2017-01-01

    The Next Generation Sequencing (NGS) technologies represent a turning point in the food inspection field, particularly for species identification in matrices composed of a blend of two or more species. In this study NGS technologies were applied by testing the usefulness of the Ion Torrent Personal Genome Machine (PGM) in seafood traceability. Sixteen commercial surimi samples produced both in EU and non-EU countries were analysed. Libraries were prepared using a universal primer pair able to amplify a short 16SrRNA fragment from a wide range of fish and cephalopod species. The mislabelling rate of the samples was also evaluated. Overall, DNA from 13 families, 19 genera and 16 species of fish, and from 3 families, 3 genera and 3 species of cephalopods was found with the analysis. Samples produced in non-EU countries exhibited a higher variability in their composition. 37.5% of the surimi products were found to be mislabelled. Among them, 25% voluntary declared a species different from those identified and 25% (all produced in non-EU countries) did not report the presence of molluscs on the label, posing a potential health threat for allergic consumers. The use of vulnerable species was also proved. Although the protocol should be further optimized, PGM platform proved to be a useful tool for the analysis of complex, highly processed products. PMID:28968423

  19. Role of a computer-generated three-dimensional laryngeal model in anatomy teaching for advanced learners.

    Science.gov (United States)

    Tan, S; Hu, A; Wilson, T; Ladak, H; Haase, P; Fung, K

    2012-04-01

    (1) To investigate the efficacy of a computer-generated three-dimensional laryngeal model for laryngeal anatomy teaching; (2) to explore the relationship between students' spatial ability and acquisition of anatomical knowledge; and (3) to assess participants' opinion of the computerised model. Forty junior doctors were randomised to undertake laryngeal anatomy study supplemented by either a three-dimensional computer model or two-dimensional images. Outcome measurements comprised a laryngeal anatomy test, the modified Vandenberg and Kuse mental rotation test, and an opinion survey. Mean scores ± standard deviations for the anatomy test were 15.7 ± 2.0 for the 'three dimensions' group and 15.5 ± 2.3 for the 'standard' group (p = 0.7222). Pearson's correlation between the rotation test scores and the scores for the spatial ability questions in the anatomy test was 0.4791 (p = 0.086, n = 29). Opinion survey answers revealed significant differences in respondents' perceptions of the clarity and 'user friendliness' of, and their preferences for, the three-dimensional model as regards anatomical study. The three-dimensional computer model was equivalent to standard two-dimensional images, for the purpose of laryngeal anatomy teaching. There was no association between students' spatial ability and functional anatomy learning. However, students preferred to use the three-dimensional model.

  20. Molecular heterogeneity assessment by next-generation sequencing and response to gefitinib of EGFR mutant advanced lung adenocarcinoma.

    Science.gov (United States)

    Bria, Emilio; Pilotto, Sara; Amato, Eliana; Fassan, Matteo; Novello, Silvia; Peretti, Umberto; Vavalà, Tiziana; Kinspergher, Stefania; Righi, Luisella; Santo, Antonio; Brunelli, Matteo; Corbo, Vincenzo; Giglioli, Eliana; Sperduti, Isabella; Milella, Michele; Chilosi, Marco; Scarpa, Aldo; Tortora, Giampaolo

    2015-05-20

    Cancer molecular heterogeneity might explain the variable response of EGFR mutant lung adenocarcinomas to tyrosine kinase inhibitors (TKIs). We assessed the mutational status of 22 cancer genes by next-generation sequencing (NGS) in poor, intermediate or good responders to first-line gefitinib. Clinical outcome was correlated with Additional Coexisting Mutations (ACMs) and the EGFR Proportion of Mutated Alleles (PMA). Thirteen ACMs were found in 10/17 patients: TP53 (n=6), KRAS (n=2), CTNNB1 (n=2), PIK3CA, SMAD4 and MET (n=1 each). TP53 mutations were exclusive of poor/intermediate responders (66.7% versus 0, p=0.009). Presence of ACMs significantly affected both PFS (median 3.0 versus 12.3 months, p=0.03) and survival (3.6 months versus not reached, p=0.03). TP53 mutation was the strongest negative modifier (median PFS 4.0 versus 14.0 months). Higher EGFR PMA was present in good versus poor/intermediate responders. Median PFS and survival were longer in patients with EGFR PMA ≥0.36 (12.0 versus 4.0 months, p=0.31; not reached versus 18.0 months, p=0.59). Patients with an EGFR PMA ≥0.36 and no ACMs fared significantly better (p=0.03), with a trend towards increased survival (p=0.06). Our exploratory data suggest that a quantitative (PMA) and qualitative (ACMs) molecular heterogeneity assessment using NGS might be useful for a better selection of patients.

  1. Reduced Volume Prototype Spacesuit Water Membrane Evaporator; A Next-Generation Evaporative Cooling System for the Advanced Extravehicular Mobility Unit Portable Life Support System

    Science.gov (United States)

    Makinen, Janice V.; Anchondo, Ian; Bue, Grant C.; Campbell, Colin; Colunga, Aaron

    2013-01-01

    Development of the Advanced Extravehicular Mobility Unit (AEMU) portable life support subsystem (PLSS) is currently under way at NASA Johnson Space Center. The AEMU PLSS features a new evaporative cooling system, the reduced volume prototype (RVP) spacesuit water membrane evaporator (SWME). The RVP SWME is the third generation of hollow fiber SWME hardware. Like its predecessors, RVP SWME provides nominal crew member and electronics cooling by flowing water through porous hollow fibers. Water vapor escapes through the hollow fiber pores, thereby cooling the liquid water that remains inside of the fibers. This cooled water is then recirculated to remove heat from the crew member and PLSS electronics. Major design improvements, including a 36% reduction in volume, reduced weight, and a more flight-like backpressure valve, facilitate the packaging of RVP SWME in the AEMU PLSS envelope. The development of these evaporative cooling systems will contribute to a more robust and comprehensive AEMU PLSS.

  2. Mating Design and Genetic Structure of a Multi-Parent Advanced Generation Intercross (MAGIC Population of Sorghum (Sorghum bicolor (L. Moench

    Directory of Open Access Journals (Sweden)

    Patrick O. Ongom

    2018-01-01

    Full Text Available Multi-parent advanced generation intercross (MAGIC populations are powerful next-generation mapping resources. We describe here the mating design and structure of the first MAGIC population in sorghum, and test its utility for mapping. The population was developed by intercrossing 19 diverse founder lines through a series of paired crosses with a genetic male sterile (MS source, followed by 10 generations of random mating. At the final stage of random mating, 1000 random fertile plants in the population were identified and subjected to six generations of selfing to produce 1000 immortal MAGIC inbred lines. The development of this sorghum MAGIC population took over 15 yr. Genotyping-by-sequencing (GBS of a subset of 200 MAGIC lines identified 79,728 SNPs, spanning high gene-rich regions. Proportion of SNPs per chromosome ranged from 6 to 15%. Structure analyses produced no evidence of population stratification, portraying the desirability of this population for genome-wide association studies (GWAS. The 19 founders formed three clusters, each with considerable genetic diversity. Further analysis showed that 73% of founder alleles segregated in the MAGIC population. Linkage disequilibrium (LD patterns depicted the MAGIC population to be highly recombined, with LD decaying to r2 ≤ 0.2 at 40 kb and down to r2 ≤ 0.1 at 220 kb. GWAS detected two known plant height genes, DWARF1 (chromosome 9 and DWARF3 (chromosome 7, and a potentially new plant height quantitative trait locus (QTL (QTL-6 on chromosome 6. The MAGIC population was found to be rich in allelic content with high fragmentation of its genome, making it fit for both gene mapping and effective marker-assisted breeding.

  3. Mating Design and Genetic Structure of a Multi-Parent Advanced Generation Intercross (MAGIC) Population of Sorghum (Sorghum bicolor(L.) Moench).

    Science.gov (United States)

    Ongom, Patrick O; Ejeta, Gebisa

    2018-01-04

    Multi-parent advanced generation intercross (MAGIC) populations are powerful next-generation mapping resources. We describe here the mating design and structure of the first MAGIC population in sorghum, and test its utility for mapping. The population was developed by intercrossing 19 diverse founder lines through a series of paired crosses with a genetic male sterile (MS) source, followed by 10 generations of random mating. At the final stage of random mating, 1000 random fertile plants in the population were identified and subjected to six generations of selfing to produce 1000 immortal MAGIC inbred lines. The development of this sorghum MAGIC population took over 15 yr. Genotyping-by-sequencing (GBS) of a subset of 200 MAGIC lines identified 79,728 SNPs, spanning high gene-rich regions. Proportion of SNPs per chromosome ranged from 6 to 15%. Structure analyses produced no evidence of population stratification, portraying the desirability of this population for genome-wide association studies (GWAS). The 19 founders formed three clusters, each with considerable genetic diversity. Further analysis showed that 73% of founder alleles segregated in the MAGIC population. Linkage disequilibrium (LD) patterns depicted the MAGIC population to be highly recombined, with LD decaying to r 2 [Formula: see text] 0.2 at 40 kb and down to r 2 [Formula: see text] 0.1 at 220 kb. GWAS detected two known plant height genes, DWARF1 (chromosome 9) and DWARF3 (chromosome 7), and a potentially new plant height quantitative trait locus (QTL) ( QTL-6 ) on chromosome 6. The MAGIC population was found to be rich in allelic content with high fragmentation of its genome, making it fit for both gene mapping and effective marker-assisted breeding. Copyright © 2018 Ongom, Ejeta.

  4. Greenhouse gas emissions from first generation ethanol derived from wheat and sugar beet in Germany – Analysis and comparison of advanced by-product utilization pathways

    International Nuclear Information System (INIS)

    Weinberg, Jana; Kaltschmitt, Martin

    2013-01-01

    Highlights: ► Ethanol production from sugar beet and wheat is investigated. ► Instead of feed production from residues by-products are used for energy production. ► Ethanol from sugar beet with biogas co-production shows lowest GHG emissions. ► For wheat pathways bran and gluten separation generates lowest GHG emissions. ► An allocation method is recommended involving co-produced fertilizer. -- Abstract: In state of the art ethanol production, by-products like vinasse from sugar beet or distiller’s dried grains with solubles (DDGSs) from wheat grains are usually used as animal feed. The drying process consumes a significant amount of energy that could be reduced by producing other valuable materials or energy carriers from these by-products. Besides resulting higher overall conversion rates and improved process efficiencies, by-products, which can be extracted or are automatically created during the various conversion steps, should be used to reduce environmental impacts as well. In this analysis, advanced pathways for the recovery and use of by-products from bio-chemical ethanol production like gluten separation from wheat starch, biogas production from stillage or vinasse and combustion of bran for electricity generation are analyzed with regard to their contribution to the greenhouse effect. Therefore, different methodological approaches are applied and compared. The analysis shows among others that ethanol from sugar beet generates less greenhouse gases (GHGs) compared to the ethanol production from wheat. The biogas production from residues and especially the use of bran for heat and electricity generation shows significant GHG reduction compared to the state of the art application. However, the methodological approach for the treatment of by-products highly influences the results. For the reproducibility of the results an energy equivalent allocation method involving the specific application of the respective co-product is recommended.

  5. NASA/DARPA advanced communications technology satellite project for evaluation of telemedicine outreach using next-generation communications satellite technology: Mayo Foundation participation.

    Science.gov (United States)

    Gilbert, B K; Mitchell, M P; Bengali, A R; Khandheria, B K

    1999-08-01

    To describe the development of telemedicine capabilities-application of remote consultation and diagnostic techniques-and to evaluate the feasibility and practicality of such clinical outreach to rural and underserved communities with limited telecommunications infrastructures. In 1992, Mayo Foundation (Rochester, Minn, Jacksonville, Fla, and Scottsdale, Ariz), the National Aeronautics and Space Administration, and the Defense Advanced Research Projects Agency collaborated to create a complex network of fiberoptic landlines, video recording systems, satellite terminals, and specially developed data translators linking Mayo sites with other locations in the continental United States on an on-demand basis. The purpose was to transmit data via the asynchronous transfer mode (ATM) digital communications protocol over the Advanced Communications Technology Satellite. The links were intended to provide a conduit for transmission of data for patient-specific consultations between physicians, evaluation of medical imagery, and medical education for clinical staffs at remote sites. Low-data-rate (LDR) experiments went live late in 1993. Mayo Clinic Rochester successfully provided medical consultation and services to 2 small regional medical facilities. High-data-rate (HDR) experiments included studies of remote digital echocardiography, store-and-forward telemedicine, cardiac catheterization, and teleconsultation for congenital heart disease. These studies combined landline data transmission with use of the satellite. The complexity of the routing paths and network components, immaturity of available software, and inexperience with existing telecommunications caused significant study delays. These experiments demonstrated that next-generation satellite technology can provide batch and real-time imagery for telemedicine. The first-generation of the ATM and satellite network technology used in these experiments created several technical problems and inconveniences that should

  6. Advancing Space Sciences through Undergraduate Research Experiences at UC Berkeley's Space Sciences Laboratory - a novel approach to undergraduate internships for first generation community college students

    Science.gov (United States)

    Raftery, C. L.; Davis, H. B.; Peticolas, L. M.; Paglierani, R.

    2015-12-01

    The Space Sciences Laboratory at UC Berkeley launched an NSF-funded Research Experience for Undergraduates (REU) program in the summer of 2015. The "Advancing Space Sciences through Undergraduate Research Experiences" (ASSURE) program recruited heavily from local community colleges and universities, and provided a multi-tiered mentorship program for students in the fields of space science and engineering. The program was focussed on providing a supportive environment for 2nd and 3rd year undergraduates, many of whom were first generation and underrepresented students. This model provides three levels of mentorship support for the participating interns: 1) the primary research advisor provides academic and professional support. 2) The program coordinator, who meets with the interns multiple times per week, provides personal support and helps the interns to assimilate into the highly competitive environment of the research laboratory. 3) Returning undergraduate interns provided peer support and guidance to the new cohort of students. The impacts of this program on the first generation students and the research mentors, as well as the lessons learned will be discussed.

  7. Final report for %22High performance computing for advanced national electric power grid modeling and integration of solar generation resources%22, LDRD Project No. 149016.

    Energy Technology Data Exchange (ETDEWEB)

    Reno, Matthew J.; Riehm, Andrew Charles; Hoekstra, Robert John; Munoz-Ramirez, Karina; Stamp, Jason Edwin; Phillips, Laurence R.; Adams, Brian M.; Russo, Thomas V.; Oldfield, Ron A.; McLendon, William Clarence, III; Nelson, Jeffrey Scott; Hansen, Clifford W.; Richardson, Bryan T.; Stein, Joshua S.; Schoenwald, David Alan; Wolfenbarger, Paul R.

    2011-02-01

    Design and operation of the electric power grid (EPG) relies heavily on computational models. High-fidelity, full-order models are used to study transient phenomena on only a small part of the network. Reduced-order dynamic and power flow models are used when analysis involving thousands of nodes are required due to the computational demands when simulating large numbers of nodes. The level of complexity of the future EPG will dramatically increase due to large-scale deployment of variable renewable generation, active load and distributed generation resources, adaptive protection and control systems, and price-responsive demand. High-fidelity modeling of this future grid will require significant advances in coupled, multi-scale tools and their use on high performance computing (HPC) platforms. This LDRD report demonstrates SNL's capability to apply HPC resources to these 3 tasks: (1) High-fidelity, large-scale modeling of power system dynamics; (2) Statistical assessment of grid security via Monte-Carlo simulations of cyber attacks; and (3) Development of models to predict variability of solar resources at locations where little or no ground-based measurements are available.

  8. Generation of advanced fire blight-resistant apple (Malus × domestica) selections of the fifth generation within 7 years of applying the early flowering approach.

    Science.gov (United States)

    Schlathölter, Ina; Jänsch, Melanie; Flachowsky, Henryk; Broggini, Giovanni Antonio Lodovico; Hanke, Magda-Viola; Patocchi, Andrea

    2018-03-14

    The approach presented here can be applied to reduce the time needed to introduce traits from wild apples into null segregant advanced selections by one-fourth. Interesting traits like resistances to pathogens are often found within the wild apple gene pool. However, the long juvenile phase of apple seedlings hampers the rapid introduction of these traits into new cultivars. The rapid crop cycle breeding approach used in this paper is based on the overexpression of the birch (Betula pendula) MADS4 transcription factor in apple. Using the early flowering line T1190 and 'Evereste' as source of the fire blight resistance (Fb_E locus), we successfully established 18 advanced selections of the fifth generation in the greenhouse within 7 years. Fifteen individuals showed the habitus expected of a regular apple seedling, while three showed very short internodes. The null segregants possessing a regular habitus maintained the high level of fire blight resistance typical for 'Evereste'. Using SSR markers, we estimated the percentage of genetic drag from 'Evereste' still associated with Fb_E on linkage group 12 (LG12). Eight out of the 18 selections had only 4% of 'Evereste' genome left. Since genotypes carrying the apple scab resistance gene Rvi6 and the fire blight resistance QTL Fb_F7 were used as parents in the course of the experiments, these resistances were also identified in some of the null segregants. One seedling is particularly interesting as, beside Fb_E, it also carries Fb_F7 heterozygously and Rvi6 homozygously. If null segregants obtained using this method will be considered as not genetically modified in Europe, as is already the case in the USA, this genotype could be a very promising parent for breeding new fire blight and scab-resistant apple cultivars in European apple breeding programs.

  9. Using SpaceClaimTD Direct for Modeling Components with Complex Geometries for the Thermal Desktop-Based Advanced Stirling Radioisotope Generator Model

    Science.gov (United States)

    Fabanich, William A., Jr.

    2014-01-01

    SpaceClaim/TD Direct has been used extensively in the development of the Advanced Stirling Radioisotope Generator (ASRG) thermal model. This paper outlines the workflow for that aspect of the task and includes proposed best practices and lessons learned. The ASRG thermal model was developed to predict component temperatures and power output and to provide insight into the prime contractor's thermal modeling efforts. The insulation blocks, heat collectors, and cold side adapter flanges (CSAFs) were modeled with this approach. The model was constructed using mostly TD finite difference (FD) surfaces/solids. However, some complex geometry could not be reproduced with TD primitives while maintaining the desired degree of geometric fidelity. Using SpaceClaim permitted the import of original CAD files and enabled the defeaturing/repair of those geometries. TD Direct (a SpaceClaim add-on from CRTech) adds features that allowed the "mark-up" of that geometry. These so-called "mark-ups" control how finite element (FE) meshes are to be generated through the "tagging" of features (e.g. edges, solids, surfaces). These tags represent parameters that include: submodels, material properties, material orienters, optical properties, and radiation analysis groups. TD aliases were used for most tags to allow analysis to be performed with a variety of parameter values. "Domain-tags" were also attached to individual and groups of surfaces and solids to allow them to be used later within TD to populate objects like, for example, heaters and contactors. These tools allow the user to make changes to the geometry in SpaceClaim and then easily synchronize the mesh in TD without having to redefine the objects each time as one would if using TDMesher. The use of SpaceClaim/TD Direct helps simplify the process for importing existing geometries and in the creation of high fidelity FE meshes to represent complex parts. It also saves time and effort in the subsequent analysis.

  10. Using SpaceClaim/TD Direct for Modeling Components with Complex Geometries for the Thermal Desktop-Based Advanced Stirling Radioisotope Generator Model

    Science.gov (United States)

    Fabanich, William

    2014-01-01

    SpaceClaim/TD Direct has been used extensively in the development of the Advanced Stirling Radioisotope Generator (ASRG) thermal model. This paper outlines the workflow for that aspect of the task and includes proposed best practices and lessons learned. The ASRG thermal model was developed to predict component temperatures and power output and to provide insight into the prime contractors thermal modeling efforts. The insulation blocks, heat collectors, and cold side adapter flanges (CSAFs) were modeled with this approach. The model was constructed using mostly TD finite difference (FD) surfaces solids. However, some complex geometry could not be reproduced with TD primitives while maintaining the desired degree of geometric fidelity. Using SpaceClaim permitted the import of original CAD files and enabled the defeaturing repair of those geometries. TD Direct (a SpaceClaim add-on from CRTech) adds features that allowed the mark-up of that geometry. These so-called mark-ups control how finite element (FE) meshes were generated and allowed the tagging of features (e.g. edges, solids, surfaces). These tags represent parameters that include: submodels, material properties, material orienters, optical properties, and radiation analysis groups. TD aliases were used for most tags to allow analysis to be performed with a variety of parameter values. Domain-tags were also attached to individual and groups of surfaces and solids to allow them to be used later within TD to populate objects like, for example, heaters and contactors. These tools allow the user to make changes to the geometry in SpaceClaim and then easily synchronize the mesh in TD without having to redefine these objects each time as one would if using TD Mesher.The use of SpaceClaim/TD Direct has helped simplify the process for importing existing geometries and in the creation of high fidelity FE meshes to represent complex parts. It has also saved time and effort in the subsequent analysis.

  11. Third-generation dual-source 70-kVp chest CT angiography with advanced iterative reconstruction in young children: image quality and radiation dose reduction.

    Science.gov (United States)

    Rompel, Oliver; Glöckler, Martin; Janka, Rolf; Dittrich, Sven; Cesnjevar, Robert; Lell, Michael M; Uder, Michael; Hammon, Matthias

    2016-04-01

    Many technical updates have been made in multi-detector CT. To evaluate image quality and radiation dose of high-pitch second- and third-generation dual-source chest CT angiography and to assess the effects of different levels of advanced modeled iterative reconstruction (ADMIRE) in newborns and children. Chest CT angiography (70 kVp) was performed in 42 children (age 158 ± 267 days, range 1-1,194 days). We evaluated subjective and objective image quality, and radiation dose with filtered back projection (FBP) and different strength levels of ADMIRE. For comparison were 42 matched controls examined with a second-generation 128-slice dual-source CT-scanner (80 kVp). ADMIRE demonstrated improved objective and subjective image quality (P quality were 11.9, 10.0 and 1.9, respectively, for the 80 kVp mode and 11.2, 10.0 and 1.9 for the 70 kVp mode. With ADMIRE, the corresponding values for the 70 kVp mode were 13.7, 12.1 and 1.4 at strength level 2 and 17.6, 15.6 and 1.2 at strength level 4. Mean CTDIvol, DLP and effective dose were significantly lower with the 70-kVp mode (0.31 mGy, 5.33 mGy*cm, 0.36 mSv) compared to the 80-kVp mode (0.46 mGy, 9.17 mGy*cm, 0.62 mSv; P source CT at 70 kVp provided good objective and subjective image quality at lower radiation exposure. ADMIRE improved objective and subjective image quality.

  12. Advanced Manufacturing Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — The Advanced Manufacturing Laboratory at the University of Maryland provides the state of the art facilities for realizing next generation products and educating the...

  13. Bias-corrected targeted next-generation sequencing for rapid, multiplexed detection of actionable alterations in cell-free DNA from advanced lung cancer patients

    Science.gov (United States)

    Paweletz, Cloud P.; Sacher, Adrian G.; Raymond, Chris K.; Alden, Ryan S.; O'Connell, Allison; Mach, Stacy L.; Kuang, Yanan; Gandhi, Leena; Kirschmeier, Paul; English, Jessie M.; Lim, Lee P.; Jänne, Pasi A.; Oxnard, Geoffrey R.

    2015-01-01

    Purpose Tumor genotyping is a powerful tool for guiding non-small cell lung cancer (NSCLC) care, however comprehensive tumor genotyping can be logistically cumbersome. To facilitate genotyping, we developed a next-generation sequencing (NGS) assay using a desktop sequencer to detect actionable mutations and rearrangements in cell-free plasma DNA (cfDNA). Experimental Design An NGS panel was developed targeting 11 driver oncogenes found in NSCLC. Targeted NGS was performed using a novel methodology that maximizes on-target reads, and minimizes artifact, and was validated on DNA dilutions derived from cell lines. Plasma NGS was then blindly performed on 48 patients with advanced, progressive NSCLC and a known tumor genotype, and explored in two patients with incomplete tumor genotyping. Results NGS could identify mutations present in DNA dilutions at ≥0.4% allelic frequency with 100% sensitivity/specificity. Plasma NGS detected a broad range of driver and resistance mutations, including ALK, ROS1, and RET rearrangements, HER2 insertions, and MET amplification, with 100% specificity. Sensitivity was 77% across 62 known driver and resistance mutations from the 48 cases; in 29 cases with common EGFR and KRAS mutations, sensitivity was similar to droplet digital PCR. In two cases with incomplete tumor genotyping, plasma NGS rapidly identified a novel EGFR exon 19 deletion and a missed case of MET amplification. Conclusion Blinded to tumor genotype, this plasma NGS approach detected a broad range of targetable genomic alterations in NSCLC with no false positives including complex mutations like rearrangements and unexpected resistance mutations such as EGFR C797S. Through use of widely available vacutainers and a desktop sequencing platform, this assay has the potential to be implemented broadly for patient care and translational research. PMID:26459174

  14. Enhancing Lifestyle Change in Cardiac Patients Through the Do CHANGE System ("Do Cardiac Health: Advanced New Generation Ecosystem"): Randomized Controlled Trial Protocol.

    Science.gov (United States)

    Habibović, Mirela; Broers, Eva; Piera-Jimenez, Jordi; Wetzels, Mart; Ayoola, Idowu; Denollet, Johan; Widdershoven, Jos

    2018-02-08

    Promoting a healthy lifestyle (eg, physical activity, healthy diet) is crucial for the primary and secondary prevention of cardiac disease in order to decrease disease burden and mortality. The current trial aims to evaluate the effectiveness of the Do Cardiac Health: Advanced New Generation Ecosystem (Do CHANGE) service, which is developed to assist cardiac patients in adopting a healthy lifestyle and improving their quality of life. Cardiac patients (ie, people who have been diagnosed with heart failure, coronary artery disease, and/or hypertension) will be recruited at three pilot sites (Badalona Serveis Assistencials, Badalona, Spain [N=75]; Buddhist Tzu Chi Dalin General Hospital, Dalin, Taiwan [N=100] and Elisabeth-TweeSteden Hospital, Tilburg, The Netherlands [N=75]). Patients will be assisted by the Do Something Different (DSD) program to change their unhealthy habits and/or lifestyle. DSD has been developed to increase behavioral flexibility and subsequently adopt new (healthier) habits. In addition, patients' progress will be monitored with a number of (newly developed) devices (eg, Fitbit, Beddit, COOKiT, FLUiT), which will be integrated in one application. The Do CHANGE trial will provide us with new insights regarding the effectiveness of the proposed intervention in different cultural settings. In addition, it will give insight into what works for whom and why. The Do CHANGE service integrates new technologies into a behavior change intervention in order to change the unhealthy lifestyles of cardiac patients. The program is expected to facilitate long-term, sustainable behavioral change. Clinicaltrials.gov NCT03178305; https://clinicaltrials.gov/ct2/show/NCT03178305 (Archived by WebCite at http://www.webcitation.org/6wfWHvuyU). ©Mirela Habibović, Eva Broers, Jordi Piera-Jimenez, Mart Wetzels, Idowu Ayoola, Johan Denollet, Jos Widdershoven. Originally published in JMIR Research Protocols (http://www.researchprotocols.org), 08.02.2018.

  15. Advanced Virgo

    CERN Multimedia

    Virgo, a first-generation interferometric gravitational wave (GW) detector, located in the European Gravitational Observatory, EGO, Cascina (Pisa-Italy) and constructed by the collaboration of French and Italian institutes (CNRS and INFN) has successfully completed its long-duration data taking runs. It is now undergoing a fundamental upgrade that exploits available cutting edges technology to open an exciting new window on the universe, with the first detection of a gravitational wave signal. Advanced Virgo (AdV) is the project to upgrade the Virgo detector to a second-generation instrument. AdV will be able to scan a volume of the Universe 1000 times larger than initial Virgo. AdV will be hosted in the same infrastructures as Virgo. The Advanced VIRGO project is funded and at present carried on by a larger collaboration of institutes belonging to CNRS- France , RMKI - Hungary, INFN- Italy, Nikhef - The Netherlands Polish Academy of Science - Poland.

  16. Smashing the Stovepipe: Leveraging the GMSEC Open Architecture and Advanced IT Automation to Rapidly Prototype, Develop and Deploy Next-Generation Multi-Mission Ground Systems

    Science.gov (United States)

    Swenson, Paul

    2017-01-01

    Satellite/Payload Ground Systems - Typically highly-customized to a specific mission's use cases - Utilize hundreds (or thousands!) of specialized point-to-point interfaces for data flows / file transfers Documentation and tracking of these complex interfaces requires extensive time to develop and extremely high staffing costs Implementation and testing of these interfaces are even more cost-prohibitive, and documentation often lags behind implementation resulting in inconsistencies down the road With expanding threat vectors, IT Security, Information Assurance and Operational Security have become key Ground System architecture drivers New Federal security-related directives are generated on a daily basis, imposing new requirements on current / existing ground systems - These mandated activities and data calls typically carry little or no additional funding for implementation As a result, Ground System Sustaining Engineering groups and Information Technology staff continually struggle to keep up with the rolling tide of security Advancing security concerns and shrinking budgets are pushing these large stove-piped ground systems to begin sharing resources - I.e. Operational / SysAdmin staff, IT security baselines, architecture decisions or even networks / hosting infrastructure Refactoring these existing ground systems into multi-mission assets proves extremely challenging due to what is typically very tight coupling between legacy components As a result, many "Multi-Mission" ops. environments end up simply sharing compute resources and networks due to the difficulty of refactoring into true multi-mission systems Utilizing continuous integration / rapid system deployment technologies in conjunction with an open architecture messaging approach allows System Engineers and Architects to worry less about the low-level details of interfaces between components and configuration of systems GMSEC messaging is inherently designed to support multi-mission requirements, and

  17. Advanced Diffusion-weighted Imaging Modeling for Prostate Cancer Characterization: Correlation with Quantitative Histopathologic Tumor Tissue Composition-A Hypothesis-generating Study.

    Science.gov (United States)

    Hectors, Stefanie J; Semaan, Sahar; Song, Christopher; Lewis, Sara; Haines, George K; Tewari, Ashutosh; Rastinehad, Ardeshir R; Taouli, Bachir

    2018-03-01

    Purpose To correlate quantitative diffusion-weighted imaging (DWI) parameters derived from conventional monoexponential DWI, stretched exponential DWI, diffusion kurtosis imaging (DKI), and diffusion-tensor imaging (DTI) with quantitative histopathologic tumor tissue composition in prostate cancer in a preliminary hypothesis-generating study. Materials and Methods This retrospective institutional review board-approved study included 24 patients with prostate cancer (mean age, 63 years) who underwent magnetic resonance (MR) imaging, including high-b-value DWI and DTI at 3.0 T, before prostatectomy. The following parameters were calculated in index tumors and nontumoral peripheral zone (PZ): apparent diffusion coefficient (ADC) obtained with monoexponential fit (ADC ME ), ADC obtained with stretched exponential modeling (ADC SE ), anomalous exponent (α) obtained at stretched exponential DWI, ADC obtained with DKI modeling (ADC DKI ), kurtosis with DKI, ADC obtained with DTI (ADC DTI ), and fractional anisotropy (FA) at DTI. Parameters in prostate cancer and PZ were compared by using paired Student t tests. Pearson correlations between tumor DWI and quantitative histologic parameters (nuclear, cytoplasmic, cellular, stromal, luminal fractions) were determined. Results All DWI parameters were significantly different between prostate cancer and PZ (P < .012). ADC ME , ADC SE , and ADC DKI all showed significant negative correlation with cytoplasmic and cellular fractions (r = -0.546 to -0.435; P < .034) and positive correlation with stromal fractions (r = 0.619-0.669; P < .001). ADC DTI and FA showed correlation only with stromal fraction (r = 0.512 and -0.413, respectively; P < .045). α did not correlate with histologic parameters, whereas kurtosis showed significant correlations with histopathologic parameters (r = 0.487, 0.485, -0.422 for cytoplasmic, cellular, and stromal fractions, respectively; P < .040). Conclusion Advanced DWI methods showed significant

  18. Integration of Advanced Concepts and Vehicles Into the Next Generation Air Transportation System. Volume 1; Introduction, Key Messages, and Vehicle Attributes

    Science.gov (United States)

    Zellweger, Andres; Resnick, Herbert; Stevens, Edward; Arkind, Kenneth; Cotton William B.

    2010-01-01

    Raytheon, in partnership with NASA, is leading the way in ensuring that the future air transportation continues to be a key driver of economic growth and stability and that this system provides an environmentally friendly, safe, and effective means of moving people and goods. A Raytheon-led team of industry and academic experts, under NASA contract NNA08BA47C, looked at the potential issues and impact of introducing four new classes of advanced aircraft into the next generation air transportation system -- known as NextGen. The study will help determine where NASA should further invest in research to support the safe introduction of these new air vehicles. Small uncrewed or unmanned aerial systems (SUAS), super heavy transports (SHT) including hybrid wing body versions (HWB), very light jets (VLJ), and supersonic business jets (SSBJ) are the four classes of aircraft that we studied. Understanding each vehicle's business purpose and strategy is critical to assessing the feasibility of new aircraft operations and their impact on NextGen's architecture. The Raytheon team used scenarios created by aviation experts that depict vehicles in year 2025 operations along with scripts or use cases to understand the issues presented by these new types of vehicles. The information was then mapped into the Joint Planning and Development Office's (JPDO s) Enterprise Architecture to show how the vehicles will fit into NextGen's Concept of Operations. The team also identified significant changes to the JPDO's Integrated Work Plan (IWP) to optimize the NextGen vision for these vehicles. Using a proven enterprise architecture approach and the JPDO s Joint Planning Environment (JPE) web site helped make the leap from architecture to planning efficient, manageable and achievable. Very Light Jets flying into busy hub airports -- Supersonic Business Jets needing to climb and descend rapidly to achieve the necessary altitude Super-heavy cargo planes requiring the shortest common flight

  19. Recent advances using FcRn overexpression in transgenic animals to overcome impediments of standard antibody technologies to improve the generation of specific antibodies

    Science.gov (United States)

    Cervenak, Judit; Erdei, Anna; Goldsby, Richard A; Butler, John E

    2011-01-01

    This review illustrates the salutary effects of neonatal Fc receptor (FcRn) overexpression in significantly improving humoral immune responses in the generation of antibodies for immunotherapy and diagnostics. These include: (1) improved IgG protection; (2) augmented antigen-specific humoral immune response with larger numbers of antigen specific B cells, thus offering a wider spectrum of clones; (3) generation of antibodies against weakly immunogenic antigens; (4) significant improvements in the number and substantial developments in the diversity of hybridomas. FcRn transgenesis thus confers a number of practical benefits, including faster antibody production, higher antibody yields and improved generation of hybridomas for monoclonal antibody production. Notably, these efficiencies in polyclonal antibody production were also demonstrated in FcRn transgenic rabbits. Overall, FcRn transgenic animals yield more antibodies and provide a route to the generation of antibodies against antigens of low immunogenicity that are difficult to obtain using currently available methods. PMID:22048692

  20. Effect of automated tube voltage selection, integrated circuit detector and advanced iterative reconstruction on radiation dose and image quality of 3rd generation dual-source aortic CT angiography: An intra-individual comparison.

    Science.gov (United States)

    Mangold, Stefanie; De Cecco, Carlo N; Wichmann, Julian L; Canstein, Christian; Varga-Szemes, Akos; Caruso, Damiano; Fuller, Stephen R; Bamberg, Fabian; Nikolaou, Konstantin; Schoepf, U Joseph

    2016-05-01

    To compare, on an intra-individual basis, the effect of automated tube voltage selection (ATVS), integrated circuit detector and advanced iterative reconstruction on radiation dose and image quality of aortic CTA studies using 2nd and 3rd generation dual-source CT (DSCT). We retrospectively evaluated 32 patients who had undergone CTA of the entire aorta with both 2nd generation DSCT at 120kV using filtered back projection (FBP) (protocol 1) and 3rd generation DSCT using ATVS, an integrated circuit detector and advanced iterative reconstruction (protocol 2). Contrast-to-noise ratio (CNR) was calculated. Image quality was subjectively evaluated using a five-point scale. Radiation dose parameters were recorded. All studies were considered of diagnostic image quality. CNR was significantly higher with protocol 2 (15.0±5.2 vs 11.0±4.2; pquality analysis revealed no significant differences for evaluation of attenuation (p=0.08501) but image noise was rated significantly lower with protocol 2 (p=0.0005). Mean tube voltage and effective dose were 94.7±14.1kV and 6.7±3.9mSv with protocol 2; 120±0kV and 11.5±5.2mSv with protocol 1 (pquality in comparison to 120kV imaging with FBP. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

  1. Advanced technology for treating wastewater generated in small communities; Tecnologia avanzada en depuracion de aguas residuales demosticas en pequenos nucleos de poblacion

    Energy Technology Data Exchange (ETDEWEB)

    Bao Iglesias, M.; Bobe Vazquez, J.; Simal Campos, P.; Otero Lopez, M.; Alfonsin Solino, G.

    2009-07-01

    public bodies of water management, along with private developers and companies, are faced with a wide range of possibilities for treating wastewater generated in small communities. The economic and demographic environments in small populations determine the choice between different technical solutions in the market. This document introduce a study on characteristics of the wastewater generated in small rural communities in Galicia, and its impact on the installed wastewater treatment systems, as well as possibilities of obtaining a reusable water that can be used in these populations, thereby facilitating water and economical savings. (Author) 6 refs.

  2. Second-generation non-invasive high-throughput DNA sequencing technology in the screening of Down's syndrome in advanced maternal age women

    OpenAIRE

    ZHANG, JIAO; ZHANG, BIN

    2016-01-01

    The aim of the present study was to evaluate the efficacy of using non-invasive DNA testing technology in screening Down's syndrome among women of advanced maternal age (AMA) and to provide evidence for prenatal screening of Down's syndrome. With a double-blind design, 8 ml of peripheral venous blood samples were collected from 87 women aged ≥35 years after 12 weeks of pregnancy. All cases were recorded with unique identification cards with clinical details and followed up until delivery. All...

  3. Advanced Light Source (ALS)

    Data.gov (United States)

    Federal Laboratory Consortium — The Advanced Light Source (ALS), a world leader in soft x-ray science, generates light in the wavelengths needed for examining the atomic and electronic structure of...

  4. Comparison of advanced DSP techniques for spectrally efficient Nyquist-WDM signal generation using digital FIR filters at transmitters based on higher-order modulation formats

    Science.gov (United States)

    Weng, Yi; Wang, Junyi; Pan, Zhongqi

    2016-02-01

    To support the ever-increasing demand for high-speed optical communications, Nyquist spectral shaping serves as a promising technique to improve spectral efficiency (SE) by generating near-rectangular spectra with negligible crosstalk and inter-symbol interference in wavelength-division-multiplexed (WDM) systems. Compared with specially-designed optical methods, DSP-based electrical filters are more flexible as they can generate different filter shapes and modulation formats. However, such transmitter-side pre-filtering approach is sensitive to the limited taps of finite-impulse-response (FIR) filter, for the complexity of the required DSP and digital-to-analog converter (DAC) is limited by the cost and power consumption of optical transponder. In this paper, we investigate the performance and complexity of transmitter-side FIR-based DSP with polarization-division-multiplexing (PDM) high-order quadrature-amplitude-modulation (QAM) formats. Our results show that Nyquist 64-QAM, 16-QAM and QPSK WDM signals can be sufficiently generated by digital FIR filters with 57, 37, and 17 taps respectively. Then we explore the effects of the required spectral pre-emphasis, bandwidth and resolution on the performance of Nyquist-WDM systems. To obtain negligible OSNR penalty with a roll-off factor of 0.1, two-channel-interleaved DAC requires a Gaussian electrical filter with the bandwidth of 0.4-0.6 times of the symbol rate for PDM-64QAM, 0.35-0.65 times for PDM-16QAM, and 0.3-0.8 times for PDM-QPSK, with required DAC resolutions as 8, 7, 6 bits correspondingly. As a tradeoff, PDM-64QAM can be a promising candidate for SE improvement in next-generation optical metro networks.

  5. Alliance for NanoHealth (ANH) Training Program for the development of future generations of interdisciplinary scientists and collaborative research focused upon the advancement of nanomedicine

    Energy Technology Data Exchange (ETDEWEB)

    Gorenstein, David [Univ. of Texas Health Science Center, Houston, TX (United States)

    2013-12-23

    The objectives of this program are to promote the mission of the Department of Energy (DOE) Science, Technology, Engineering, Math (STEM) Program by recruiting students to science and engineering disciplines with the intent of mentoring and supporting the next generation of scientists; to foster interdisciplinary and collaborative research under the sponsorship of ANH for the discovery and design of nano-based materials and devices with novel structures, functions, and properties; and to prepare a diverse work force of scientists, engineers, and clinicians by utilizing the unique intellectual and physical resources to develop novel nanotechnology paradigms for clinical application.

  6. Advances in light-curing units: four generations of LED lights and clinical implications for optimizing their use: Part 2. From present to future.

    Science.gov (United States)

    Shortall, Adrian C; Palin, Will M; Jacquot, Bruno; Pelissier, Bruno

    2012-01-01

    The first part of this series of two described the history of light curing in dentistry and developments in LED lights since their introduction over 20 years ago. Current second- and third-generation LED light units have progressively replaced their halogen lamp predecessors because of their inherent advantages. The background to this, together with the clinical issues relating to light curing and the possible solutions, are outlined in the second part of this article. Finally, the innovative features of what may be seen as the first of a new fourth-generation of LED lights are described and guidance is given for the practitioner on what factors to consider when seeking to purchase a new LED light activation unit. Adequate curing in depth is fundamental to clinical success with any light-activated restoration. To achieve this goal predictably, an appropriate light source needs to be combined with materials knowledge, requisite clinical skills and attention to detail throughout the entire restoration process. As dentists increasingly use light-cured direct composites to restore large posterior restorations they need to appreciate the issues central to effective and efficient light curing and to know what to look for when seeking to purchase a new light-curing unit.

  7. Advanced oxidation of biorefractory organics in aqueous solution together with bioelectricity generation by microbial fuel cells with composite FO/GPEs

    Science.gov (United States)

    Fu, Bao-rong; Shen, Chao; Ren, Jing; Chen, Jia-yi; Zhao, Lin

    2018-03-01

    In this study, ferric oxide loading graphite particle electrodes (FO/GPEs) were prepared as cathode of a three-dimensional electrode MFC-Fenton system. The properties of the composite cathode were examined with higher surface area and more mesopores. FO/GPEs could work as both cathode and Fenton iron reagents, contributing to high oxidation activity and better performance of electricity generation. The application of FO/GPEs MFC-Fenton system on degrading p-nitrophenol presented high catalytic efficiency in a wide range of pH value. The removal of p-nitrophenol and TOC attained to about 85 % within 8 and 64 h at neutral pH, respectively. A neutral FO/GPEs MFC-Fenton oxidation mechanism was also proposed. Specifically, both the surface iron sites and dissolved iron ions catalyzed the decomposition of H2O2. As results, the generated hydroxyl radicals were used for p-nitrophenol degradation and the iron oxide was recycled.

  8. Second-generation non-invasive high-throughput DNA sequencing technology in the screening of Down's syndrome in advanced maternal age women

    Science.gov (United States)

    ZHANG, JIAO; ZHANG, BIN

    2016-01-01

    The aim of the present study was to evaluate the efficacy of using non-invasive DNA testing technology in screening Down's syndrome among women of advanced maternal age (AMA) and to provide evidence for prenatal screening of Down's syndrome. With a double-blind design, 8 ml of peripheral venous blood samples were collected from 87 women aged ≥35 years after 12 weeks of pregnancy. All cases were recorded with unique identification cards with clinical details and followed up until delivery. All the non-invasive prenatal testing results were confirmed by amniotic fluid fetal karyotyping (the gold standard of aneuploidy test), follow-up examination by neonatologists or neonatal blood karyotyping. The sensitivity, specificity and other indicators of non-invasive DNA testing technology were calculated based on the data of 87 women of AMA. Among the 87 women of AMA, 5 were cases with abnormal numbers of chromosomes (3 cases of trisomy 21, 1 case of trisomy 18 and 1 case of 47, XXX). The sensitivity and specificity reached 100% for trisomy 21, trisomy 18 and 47, XXX. The present study supports that non-invasive DNA testing is a useful method of AMA screening of Down's syndrome with 100% accuracy. Therefore, it can be used as an important alternative screening method for Down's syndrome in women of AMA. PMID:27313855

  9. Second-generation non-invasive high-throughput DNA sequencing technology in the screening of Down's syndrome in advanced maternal age women.

    Science.gov (United States)

    Zhang, Jiao; Zhang, Bin

    2016-06-01

    The aim of the present study was to evaluate the efficacy of using non-invasive DNA testing technology in screening Down's syndrome among women of advanced maternal age (AMA) and to provide evidence for prenatal screening of Down's syndrome. With a double-blind design, 8 ml of peripheral venous blood samples were collected from 87 women aged ≥35 years after 12 weeks of pregnancy. All cases were recorded with unique identification cards with clinical details and followed up until delivery. All the non-invasive prenatal testing results were confirmed by amniotic fluid fetal karyotyping (the gold standard of aneuploidy test), follow-up examination by neonatologists or neonatal blood karyotyping. The sensitivity, specificity and other indicators of non-invasive DNA testing technology were calculated based on the data of 87 women of AMA. Among the 87 women of AMA, 5 were cases with abnormal numbers of chromosomes (3 cases of trisomy 21, 1 case of trisomy 18 and 1 case of 47, XXX). The sensitivity and specificity reached 100% for trisomy 21, trisomy 18 and 47, XXX. The present study supports that non-invasive DNA testing is a useful method of AMA screening of Down's syndrome with 100% accuracy. Therefore, it can be used as an important alternative screening method for Down's syndrome in women of AMA.

  10. Recent advances in the production of value added chemicals and lipids utilizing biodiesel industry generated crude glycerol as a substrate - Metabolic aspects, challenges and possibilities: An overview.

    Science.gov (United States)

    Vivek, Narisetty; Sindhu, Raveendran; Madhavan, Aravind; Anju, Alphonsa Jose; Castro, Eulogio; Faraco, Vincenza; Pandey, Ashok; Binod, Parameswaran

    2017-09-01

    One of the major ecological concerns associated with biodiesel production is the generation of waste/crude glycerol during the trans-esterification process. Purification of this crude glycerol is not economically viable. In this context, the development of an efficient and economically viable strategy would be biotransformation reactions converting the biodiesel derived crude glycerol into value added chemicals. Hence the process ensures the sustainability and waste management in biodiesel industry, paving a path to integrated biorefineries. This review addresses a waste to wealth approach for utilization of crude glycerol in the production of value added chemicals, current trends, challenges, future perspectives, metabolic approaches and the genetic tools developed for the improved synthesis over wild type microorganisms were described. Copyright © 2017 Elsevier Ltd. All rights reserved.

  11. Operating parameters of a reactor for early demonstration of electric power generation and the expansion by realization of advanced tokamak plasma

    International Nuclear Information System (INIS)

    Okano, Kunihiko; Asaoka, Yoshiyuki; Hiwatari, Ryoji

    2004-01-01

    Beam driven stable equilibria for a conceptual reactor, Demo-CREST, which was designed for early demonstration of electric power generation, has been investigated. Considering current profiles driven by neutral beams, the attainable normalized beta β N with a stabilization wall is about 3.4 with a normal shear (NS). With reversed shear (RS), a higher β N is attainable. The stable equilibria up to 4.0 can be sustained by a couple of On- and Off-axis beams. In the range of 1.9 N N = 1.9 which is the base design point of Demo-CREST. In the case of RS operation with β N 4.0, the density ratio to the Greenwald limit can be maintain at about unity if high temperature operation with T e > 20 kV is allowable. (author)

  12. Exploring new potentials and generating hypothesis for management of locally advanced head neck cancer: Analysis of pooled data from two phase II trials

    Directory of Open Access Journals (Sweden)

    Chufal Kundan

    2010-01-01

    Full Text Available Background: To study the long term results of two phase II concurrent chemoradiotherapy protocols and conduct pooled data analysis with special emphasis on nodal density. Materials and Methods: In the period from April 2001 to May 2003, phase II Mitomycin C (MMC and late chemo-intensification (LCI protocols were started in the same institute, enrolling 69 and 74 patients respectively. Long term results for these individual trials are reported along with pooled data analysis. Results: Median follow-up time for whole group, MMC protocol and LCI protocol was 43.8 months (SD619.8, 55 months (SD 618.5 and 47.5 months (SD 620.9 respectively. LRFS, DFS and OS at five years for whole group was 59.4, 43.5 and 47.1% respectively, for MMC protocol was 59.9, 45.5 and 49.5% respectively and for LCI, protocol was 53.6%, 41.5% and 44.4% respectively. Subgroup analysis revealed that MMC protocol was more effective than LCI protocol in terms of DFS and OS in patients with hypo dense nodes while opposite was true for Isodense nodes. Multivariate analysis revealed nodal density as an independent variable that had an impact on treatment outcome. Risk of death in patients with hypo dense nodes was 2.91 times that of Isodense nodes. Conclusions: Innovative and pragmatic approach is required to address locally advanced head neck cancer. Long term results for MMC and LCI protocols are encouraging. Integrating the basic concepts of these protocols may help develop new protocols, which will facilitate the search for the optimal solution.

  13. Fine mapping of complex traits in non-model species: using next generation sequencing and advanced intercross lines in Japanese quail

    Science.gov (United States)

    2012-01-01

    Background As for other non-model species, genetic analyses in quail will benefit greatly from a higher marker density, now attainable thanks to the evolution of sequencing and genotyping technologies. Our objective was to obtain the first genome wide panel of Japanese quail SNP (Single Nucleotide Polymorphism) and to use it for the fine mapping of a QTL for a fear-related behaviour, namely tonic immobility, previously localized on Coturnix japonica chromosome 1. To this aim, two reduced representations of the genome were analysed through high-throughput 454 sequencing: AFLP (Amplified Fragment Length Polymorphism) fragments as representatives of genomic DNA, and EST (Expressed Sequence Tag) as representatives of the transcriptome. Results The sequencing runs produced 399,189 and 1,106,762 sequence reads from cDNA and genomic fragments, respectively. They covered over 434 Mb of sequence in total and allowed us to detect 17,433 putative SNP. Among them, 384 were used to genotype two Advanced Intercross Lines (AIL) obtained from three quail lines differing for duration of tonic immobility. Despite the absence of genotyping for founder individuals in the analysis, the previously identified candidate region on chromosome 1 was refined and led to the identification of a candidate gene. Conclusions These data confirm the efficiency of transcript and AFLP-sequencing for SNP discovery in a non-model species, and its application to the fine mapping of a complex trait. Our results reveal a significant association of duration of tonic immobility with a genomic region comprising the DMD (dystrophin) gene. Further characterization of this candidate gene is needed to decipher its putative role in tonic immobility in Coturnix. PMID:23066875

  14. Fine mapping of complex traits in non-model species: using next generation sequencing and advanced intercross lines in Japanese quail

    Directory of Open Access Journals (Sweden)

    Frésard Laure

    2012-10-01

    Full Text Available Abstract Background As for other non-model species, genetic analyses in quail will benefit greatly from a higher marker density, now attainable thanks to the evolution of sequencing and genotyping technologies. Our objective was to obtain the first genome wide panel of Japanese quail SNP (Single Nucleotide Polymorphism and to use it for the fine mapping of a QTL for a fear-related behaviour, namely tonic immobility, previously localized on Coturnix japonica chromosome 1. To this aim, two reduced representations of the genome were analysed through high-throughput 454 sequencing: AFLP (Amplified Fragment Length Polymorphism fragments as representatives of genomic DNA, and EST (Expressed Sequence Tag as representatives of the transcriptome. Results The sequencing runs produced 399,189 and 1,106,762 sequence reads from cDNA and genomic fragments, respectively. They covered over 434 Mb of sequence in total and allowed us to detect 17,433 putative SNP. Among them, 384 were used to genotype two Advanced Intercross Lines (AIL obtained from three quail lines differing for duration of tonic immobility. Despite the absence of genotyping for founder individuals in the analysis, the previously identified candidate region on chromosome 1 was refined and led to the identification of a candidate gene. Conclusions These data confirm the efficiency of transcript and AFLP-sequencing for SNP discovery in a non-model species, and its application to the fine mapping of a complex trait. Our results reveal a significant association of duration of tonic immobility with a genomic region comprising the DMD (dystrophin gene. Further characterization of this candidate gene is needed to decipher its putative role in tonic immobility in Coturnix.

  15. Glucagon-like peptide-1 receptor agonist inhibits asymmetric dimethylarginine generation in the kidney of streptozotocin-induced diabetic rats by blocking advanced glycation end product-induced protein arginine methyltranferase-1 expression.

    Science.gov (United States)

    Ojima, Ayako; Ishibashi, Yuji; Matsui, Takanori; Maeda, Sayaka; Nishino, Yuri; Takeuchi, Masayoshi; Fukami, Kei; Yamagishi, Sho-ichi

    2013-01-01

    Advanced glycation end products (AGEs) and their receptor (RAGE) play a role in diabetic nephropathy. Asymmetric dimethylarginine (ADMA), an endogenous inhibitor of nitric oxide synthase, contributes to diabetic nephropathy. We have found that glucagon-like peptide-1 (GLP-1) inhibits the AGE-induced inflammatory reactions in endothelial cells. However, effects of GLP-1 on the AGE-RAGE-ADMA axis are unknown. This study examined the effects of GLP-1 on reactive oxygen species (ROS) generation, gene expression of protein arginine methyltransfetase-1 (PRMT-1), an enzyme that mainly generates ADMA, and ADMA levels in human proximal tubular cells. Streptozotocin-induced diabetic rats received continuous i.p. infusion of 0.3 μg of vehicle or 1.5 μg of the GLP-1 analog exendin-4 per kilogram of body weight for 2 weeks. We further investigated whether and how exendin-4 treatment reduced ADMA levels and renal damage in streptozotocin-induced diabetic rats. GLP-1 inhibited the AGE-induced RAGE and PRMT-1 gene expression, ROS, and ADMA generation in tubular cells, which were blocked by small-interfering RNAs raised against GLP-1 receptor. Exendin-4 treatment decreased gene expression of Rage, Prmt-1, Icam-1, and Mcp-1 and ADMA level; reduced urinary excretions of 8-hydroxy-2'-deoxyguanosine and albumin; and improved histopathologic changes of the kidney in diabetic rats. Our present study suggests that GLP-1 receptor agonist may inhibit the AGE-RAGE-mediated ADMA generation by suppressing PRMT-1 expression via inhibition of ROS generation, thereby protecting against the development and progression of diabetic nephropathy. Copyright © 2013 American Society for Investigative Pathology. Published by Elsevier Inc. All rights reserved.

  16. Selective Oxidation of a 0.1C-6Mn-2Si Third Generation Advanced High-Strength Steel During Dew-Point Controlled Annealing

    Science.gov (United States)

    Pourmajidian, Maedeh; McDermid, Joseph R.

    2018-03-01

    The present study investigates the selective oxidation of a 0.1C-6Mn-2Si medium-Mn advanced high-strength steel during austenization annealing heat treatments as a function of process atmosphere oxygen partial pressure and annealing time. It was determined that the surface oxide growth kinetics followed a parabolic rate law with the minimum rate belonging to the lowest oxygen partial pressure atmosphere at a dew point of 223 K (- 50 °C). The chemistry of the surface and subsurface oxides was studied using STEM + EELS on the sample cross sections, and it was found that the surface oxides formed under the 223 K (- 50 °C) dew-point atmosphere consisted of a layered configuration of SiO2, MnSiO3, and MnO, while in the case of the higher pO2 process atmospheres, only MnO was detected at the surface. Consistent with the Wagner calculations, it was shown that the transition to internal oxidation for Mn occurred under the 243 K (- 30 °C) and 278 K (+ 5 °C) dew-point atmospheres. However, the predictions of the external to internal oxidation for Si using the Wagner model did not correlate well with the experimental findings nor did the predictions of the Mataigne et al. model for multi-element alloys. Investigations of the internal oxide network at the grain boundaries revealed a multilayer oxide structure composed of amorphous SiO2 and crystalline MnSiO3, respectively, at the oxide core and outer shell. A mechanism for the formation of the oxide morphologies observed, based on kinetic and thermodynamic factors, was proposed. It is expected that only the fine and nodule-like MnO oxides formed on the surface of the samples annealed under the 278 K (+ 5 °C) dew-point process atmosphere for 60 and 120 seconds are sufficiently thin and of the desired dispersed morphology to promote reactive wetting by the molten galvanizing bath.

  17. Component Test Facility (Comtest) Phase 1 Engineering For 760°C (1400°F) Advanced Ultrasupercritical (A-USC) Steam Generator Development

    Energy Technology Data Exchange (ETDEWEB)

    Weitzel, Paul [Babcock & Wilcox Power Generation Group, Inc., Barberton, OH (United States)

    2016-05-13

    The Babcock & Wilcox Company (B&W) performed a Pre-Front End Engineering Design (Pre-FEED) of an A-USC steam superheater for a proposed component test program achieving 760°C (1400°F) steam temperature. This would lead to follow-on work in a Phase 2 and Phase 3 that would involve detail design, manufacturing, construction and operation of the ComTest. Phase 1 results have provided the engineering data necessary for proceeding to the next phase of ComTest. The steam generator superheater would subsequently supply the steam to an A-USC prototype intermediate pressure steam turbine. The ComTest program is important in that it will place functioning A-USC components in operation and in coordinated boiler and turbine service. It is also important to introduce the power plant operation and maintenance personnel to the level of skills required and provide the first background experience with hands-on training. The project will provide a means to exercise the complete supply chain events required in order to practice and perfect the process for A-USC power plant design, supply, manufacture, construction, commissioning, operation and maintenance. Representative participants will then be able to transfer knowledge and recommendations to the industry. ComTest is conceived in the manner of using a separate standalone plant facility that will not jeopardize the host facility or suffer from conflicting requirements in the host plant’s mission that could sacrifice the nickel alloy components and not achieve the testing goals. ComTest will utilize smaller quantities of the expensive materials and reduce the risk in the first operational practice for A-USC technology in the United States. Components at suitable scale in ComTest provide more assurance before putting them into practice in the full size A-USC demonstration plant.

  18. Third-generation dual-source CT of the neck using automated tube voltage adaptation in combination with advanced modeled iterative reconstruction: evaluation of image quality and radiation dose

    International Nuclear Information System (INIS)

    Scholtz, Jan-Erik; Wichmann, Julian L.; Huesers, Kristina; Albrecht, Moritz H.; Beeres, Martin; Bauer, Ralf W.; Vogl, Thomas J.; Bodelle, Boris

    2016-01-01

    To evaluate image quality and radiation dose in third-generation dual-source computed tomography (DSCT) of the neck using automated tube voltage adaptation (TVA) with advanced modelled iterative reconstruction (ADMIRE) algorithm. One hundred and sixteen patients were retrospectively evaluated. Group A (n = 59) was examined on second-generation DSCT with automated TVA and filtered back projection. Group B (n = 57) was examined on a third-generation DSCT with automated TVA and ADMIRE. Age, body diameter, attenuation of several anatomic structures, noise, signal-to-noise ratio (SNR), contrast-to-noise ratio (CNR), radiation dose (CTDI vol ) and size-specific dose estimates (SSDE) were assessed. Diagnostic acceptability was rated by three readers. Age (p = 0.87) and body diameter (p = 0.075) did not differ significantly. Tube voltage in Group A was set automatically to 100 kV for all patients (n = 59), and to 70 kV (n = 2), 80 kV (n = 5), and 90 kV (n = 50) in Group B. Noise was reduced and CNR was increased significantly (p < 0.001). Diagnostic acceptability was rated high in both groups, with better ratings in Group B (p < 0.001). SSDE was reduced by 34 % in Group B (20.38 ± 1.63 mGy vs. 13.04 ± 1.50 mGy, p < 0.001). Combination of automated TVA and ADMIRE in neck CT using third-generation DSCT results in a substantial radiation dose reduction with low noise and increased CNR. (orig.)

  19. Advanced Ceramics

    International Nuclear Information System (INIS)

    1989-01-01

    The First Florida-Brazil Seminar on Materials and the Second State Meeting about new materials in Rio de Janeiro State show the specific technical contribution in advanced ceramic sector. The others main topics discussed for the development of the country are the advanced ceramic programs the market, the national technic-scientific capacitation, the advanced ceramic patents, etc. (C.G.C.) [pt

  20. Genotype by environment interaction of advanced generation ...

    African Journals Online (AJOL)

    Cette étude était conduite dans le but de déterminer l'adaptation des nouvelles lignées de générations avancées du soja pour identifier des lignées stables à haut rendement, l'environnement le plus idéal pour ce test et, déterminer la présence des méga environnement dans le pays. Vingt et une lignées de générations ...

  1. Diagnostic Performance of an Advanced Modeled Iterative Reconstruction Algorithm for Low-Contrast Detectability with a Third-Generation Dual-Source Multidetector CT Scanner: Potential for Radiation Dose Reduction in a Multireader Study.

    Science.gov (United States)

    Solomon, Justin; Mileto, Achille; Ramirez-Giraldo, Juan Carlos; Samei, Ehsan

    2015-06-01

    To assess the effect of radiation dose reduction on low-contrast detectability by using an advanced modeled iterative reconstruction (ADMIRE; Siemens Healthcare, Forchheim, Germany) algorithm in a contrast-detail phantom with a third-generation dual-source multidetector computed tomography (CT) scanner. A proprietary phantom with a range of low-contrast cylindrical objects, representing five contrast levels (range, 5-20 HU) and three sizes (range, 2-6 mm) was fabricated with a three-dimensional printer and imaged with a third-generation dual-source CT scanner at various radiation dose index levels (range, 0.74-5.8 mGy). Image data sets were reconstructed by using different section thicknesses (range, 0.6-5.0 mm) and reconstruction algorithms (filtered back projection [FBP] and ADMIRE with a strength range of three to five). Eleven independent readers blinded to technique and reconstruction method assessed all data sets in two reading sessions by measuring detection accuracy with a two-alternative forced choice approach (first session) and by scoring the total number of visible object groups (second session). Dose reduction potentials based on both reading sessions were estimated. Results between FBP and ADMIRE were compared by using both paired t tests and analysis of variance tests at the 95% significance level. During the first session, detection accuracy increased with increasing contrast, size, and dose index (diagnostic accuracy range, 50%-87%; interobserver variability, ±7%). When compared with FBP, ADMIRE improved detection accuracy by 5.2% on average across the investigated variables (P material is available for this article. RSNA, 2015

  2. Advance Directives

    Science.gov (United States)

    ... Types Bladder Cancer Breast Cancer Colorectal Cancer Kidney (Renal Cell) Cancer Leukemia Liver Cancer Lung Cancer Lymphoma ... about advance directives. Two well-known ones are: Aging With Dignity Aging with Dignity is a national ...

  3. AdvancED Flex 4

    CERN Document Server

    Tiwari, Shashank; Schulze, Charlie

    2010-01-01

    AdvancED Flex 4 makes advanced Flex 4 concepts and techniques easy. Ajax, RIA, Web 2.0, mashups, mobile applications, the most sophisticated web tools, and the coolest interactive web applications are all covered with practical, visually oriented recipes. * Completely updated for the new tools in Flex 4* Demonstrates how to use Flex 4 to create robust and scalable enterprise-grade Rich Internet Applications.* Teaches you to build high-performance web applications with interactivity that really engages your users.* What you'll learn Practiced beginners and intermediate users of Flex, especially

  4. Advances in microwaves

    CERN Document Server

    Young, Leo

    1967-01-01

    Advances in Microwaves, Volume 2 focuses on the developments in microwave solid-state devices and circuits. This volume contains six chapters that also describe the design and applications of diplexers and multiplexers. The first chapter deals with the parameters of the tunnel diode, oscillators, amplifiers and frequency converter, followed by a simple physical description and the basic operating principles of the solid state devices currently capable of generating coherent microwave power, including transistors, harmonic generators, and tunnel, avalanche transit time, and diodes. The next ch

  5. Generating Units

    Data.gov (United States)

    Department of Homeland Security — Generating Units are any combination of physically connected generators, reactors, boilers, combustion turbines, and other prime movers operated together to produce...

  6. Advance of accelerator technology

    Energy Technology Data Exchange (ETDEWEB)

    Kamitubo, Hiromichi

    1987-08-01

    At first, accelerators were developed for the research on atomic nuclei, but as the research on the components of natural world advanced, they were made larger so as to reach higher energy, and developed so that diverse particles can be accelerated. The energy attainable with accelerators has increased to ten times in six years. To the advance of accelerators, the development of acceleration principle due to new idea or the development of the technology related to accelerators accompanied without exception. In particular, as accelerators became large scale, and their construction requires large amount of money, attention is paid to the technical development required for the construction of new accelerators as the extending effect which brings forth the technical innovation in the society. In this paper, the technical advance which is common to accelerators is outlined. As the components indispensable to accelerators, there are charged particle generators, accelerating electric field generators, vaccumizing facilities, control system, diagnostic system and so on. As to new accelerating principles, the materialization of collision type rings and beam cooling is worthy of special mention. The research on computer-aided accelerators and the techniques of accelerating electric field generation, vaccumizing, electromagnets, ion sources and others are reported. (Kako, I.).

  7. Advanced calculus

    CERN Document Server

    Nickerson, HK; Steenrod, NE

    2011-01-01

    ""This book is a radical departure from all previous concepts of advanced calculus,"" declared the Bulletin of the American Mathematics Society, ""and the nature of this departure merits serious study of the book by everyone interested in undergraduate education in mathematics."" Classroom-tested in a Princeton University honors course, it offers students a unified introduction to advanced calculus. Starting with an abstract treatment of vector spaces and linear transforms, the authors introduce a single basic derivative in an invariant form. All other derivatives - gradient, divergent, curl,

  8. Advancing Leadership

    OpenAIRE

    Penny L. Tenuto

    2014-01-01

    Preparing students to become active citizens and contributors to a democratic society is premised on teaching democratic principles and modeling standards of democratic practice at all levels of education. The purpose of this integrative literature review is to establish a conceptual framework grounded in literature and a model for cultivating democratic professional practice in education (DPPE) to advance leadership f...

  9. Technological Advancements

    Science.gov (United States)

    Kennedy, Mike

    2010-01-01

    The influx of technology has brought significant improvements to school facilities. Many of those advancements can be found in classrooms, but when students head down the hall to use the washrooms, they are likely to find a host of technological innovations that have improved conditions in that part of the building. This article describes modern…

  10. Generational diversity.

    Science.gov (United States)

    Kramer, Linda W

    2010-01-01

    Generational diversity has proven challenges for nurse leaders, and generational values may influence ideas about work and career planning. This article discusses generational gaps, influencing factors and support, and the various generational groups present in today's workplace as well as the consequences of need addressing these issues. The article ends with a discussion of possible solutions.

  11. Steam generator life management

    International Nuclear Information System (INIS)

    Tapping, R.L.; Nickerson, J.; Spekkens, P.; Maruska, C.

    1998-01-01

    Steam generators are a critical component of a nuclear power reactor, and can contribute significantly to station unavailability, as has been amply demonstrated in Pressurized Water Reactors (PWRs). CANDU steam generators are not immune to steam generator degradation, and the variety of CANDU steam generator designs and tube materials has led to some unexpected challenges. However, aggressive remedial actions, and careful proactive maintenance activities, have led to a decrease in steam generator-related station unavailability of Canadian CANDUs. AECL and the CANDU utilities have defined programs that will enable existing or new steam generators to operate effectively for 40 years. Research and development work covers corrosion and mechanical degradation of tube bundles and internals, chemistry, thermal hydraulics, fouling, inspection and cleaning, as well as provision for specially tool development for specific problem solving. A major driving force is development of CANDU-specific fitness-for-service guidelines, including appropriate inspection and monitoring technology to measure steam generator condition. Longer-range work focuses on development of intelligent on-line monitoring for the feedwater system and steam generator. New designs have reduced risk of corrosion and fouling, are more easily inspected and cleaned, and are less susceptible to mechanical damage. The Canadian CANDU utilities have developed programs for remedial actions to combat degradation of performance (Gentilly-2, Point Lepreau, Bruce A/B, Pickering A/B), and have developed strategic plans to ensure that good future operation is ensured. This report shows how recent advances in cleaning technology are integrated into a life management strategy, discusses downcomer flow measurement as a means of monitoring steam generator condition, and describes recent advances in hideout return as a life management tool. The research and development program, as well as operating experience, has identified

  12. Method of an integrated and advanced evaluation of vulnerability. Conceptional-methodical fundamentals and examplary implementation for the water household, power generation and energetic utilisation of wood under climatic change; Methode einer integrierten und erweiterten Vulnerabilitaetsbewertung. Konzeptionell-methodische Grundlagen und exemplarische Umsetzung fuer Wasserhaushalt, Stromerzeugung und energetische Nutzung von Holz unter Klimawandel

    Energy Technology Data Exchange (ETDEWEB)

    Weisz, Helga; Koch, Hagen; Lasch, Petra [Potsdam-Institut fuer Klimafolgenforschung e.V. (Germany)] [and others

    2013-07-15

    Actually, in Germany there are more than hundred investigations on the consequences of the climatic change. It is difficult to evaluate the vulnerability of Germany against the climatic change. Under this aspect, the authors of the contributions report on a method of an integrated and advanced evaluation of vulnerability: Conceptional-methodical fundamentals and exemplary implementation for water household, power generation and energetic utilization of wood under climatic change.

  13. Generation by Generation Correlation and Path Analysis for Yield ...

    African Journals Online (AJOL)

    Six advanced generations (F7 - F12) of tomato hybrids were evaluated in the Department of Crop Science Research Farm, University of Nigeria, Nsukka from 2004 to 2008 to estimate the magnitude of character association of yield and yield related attributes in each filial generation. Traits under focus were days to flowering, ...

  14. Advanced Combustion

    Energy Technology Data Exchange (ETDEWEB)

    Holcomb, Gordon R. [NETL

    2013-03-11

    The activity reported in this presentation is to provide the mechanical and physical property information needed to allow rational design, development and/or choice of alloys, manufacturing approaches, and environmental exposure and component life models to enable oxy-fuel combustion boilers to operate at Ultra-Supercritical (up to 650{degrees}C & between 22-30 MPa) and/or Advanced Ultra-Supercritical conditions (760{degrees}C & 35 MPa).

  15. Instant Generation

    Science.gov (United States)

    Loveland, Elaina

    2017-01-01

    Generation Z students (born between 1995-2010) have replaced millennials on college campuses. Generation Z students are entrepreneurial, desire practical skills with their education, and are concerned about the cost of college. This article presents what need to be known about this new generation of students.

  16. Isotope generator

    International Nuclear Information System (INIS)

    1979-01-01

    The patent describes an isotope generator incorporating the possibility of stopping elution before the elution vessel is completely full. Sterile ventilation of the whole system can then occur, including of both generator reservoir and elution vessel. A sterile, and therefore pharmaceutically acceptable, elution fluid is thus obtained and the interior of the generator is not polluted with non-sterile air. (T.P.)

  17. Accelerating development of advanced inverters :

    Energy Technology Data Exchange (ETDEWEB)

    Neely, Jason C.; Gonzalez, Sigifredo; Ropp, Michael; Schutz, Dustin

    2013-11-01

    The high penetration of utility interconnected photovoltaic (PV) systems is causing heightened concern over the effect that variable renewable generation will have on the electrical power system (EPS). These concerns have initiated the need to amend the utility interconnection standard to allow advanced inverter control functionalities that provide: (1) reactive power control for voltage support, (2) real power control for frequency support and (3) better tolerance of grid disturbances. These capabilities are aimed at minimizing the negative impact distributed PV systems may have on EPS voltage and frequency. Unfortunately, these advanced control functions may interfere with island detection schemes, and further development of advanced inverter functions requires a study of the effect of advanced functions on the efficacy of antiislanding schemes employed in industry. This report summarizes the analytical, simulation and experimental work to study interactions between advanced inverter functions and anti-islanding schemes being employed in distributed PV systems.

  18. Advanced teleoperation in nuclear applications

    International Nuclear Information System (INIS)

    Hamel, W.R.; Feldman, M.J.; Martin, H.L.

    1984-01-01

    A new generation of integrated remote maintenance systems is being developed to meet the needs of future nuclear fuel reprocessing at the Oak Ridge National Laboratory. Development activities cover all aspects of an advanced teleoperated maintenance system with particular emphasis on a new force-reflecting servomanipulator concept. The new manipulator, called the advanced servomanipulator, is microprocessor controlled and is designed to achieve force-reflection performance near that of mechanical master/slave manipulators. The advanced servomanipulator uses a gear-drive transmission which permits modularization for remote maintainability (by other advanced servomanipulators) and increases reliability. Human factors analysis has been used to develop an improved man/machine interface concept based upon colorgraphic displays and menu-driven tough screens. Initial test and evaluation of two advanced servomanipulator slave arms and several other development components have begun. 9 references, 5 figures

  19. Modular Stirling Radioisotope Generator

    Science.gov (United States)

    Schmitz, Paul C.; Mason, Lee S.; Schifer, Nicholas A.

    2016-01-01

    High-efficiency radioisotope power generators will play an important role in future NASA space exploration missions. Stirling Radioisotope Generators (SRGs) have been identified as a candidate generator technology capable of providing mission designers with an efficient, high-specific-power electrical generator. SRGs high conversion efficiency has the potential to extend the limited Pu-238 supply when compared with current Radioisotope Thermoelectric Generators (RTGs). Due to budgetary constraints, the Advanced Stirling Radioisotope Generator (ASRG) was canceled in the fall of 2013. Over the past year a joint study by NASA and the Department of Energy (DOE) called the Nuclear Power Assessment Study (NPAS) recommended that Stirling technologies continue to be explored. During the mission studies of the NPAS, spare SRGs were sometimes required to meet mission power system reliability requirements. This led to an additional mass penalty and increased isotope consumption levied on certain SRG-based missions. In an attempt to remove the spare power system, a new generator architecture is considered, which could increase the reliability of a Stirling generator and provide a more fault-tolerant power system. This new generator called the Modular Stirling Radioisotope Generator (MSRG) employs multiple parallel Stirling convertor/controller strings, all of which share the heat from the General Purpose Heat Source (GPHS) modules. For this design, generators utilizing one to eight GPHS modules were analyzed, which provided about 50 to 450 W of direct current (DC) to the spacecraft, respectively. Four Stirling convertors are arranged around each GPHS module resulting in from 4 to 32 Stirling/controller strings. The convertors are balanced either individually or in pairs, and are radiatively coupled to the GPHS modules. Heat is rejected through the housing/radiator, which is similar in construction to the ASRG. Mass and power analysis for these systems indicate that specific

  20. Generation of Soluble Advanced Glycation End Products Receptor (sRAGE)-Binding Ligands during Extensive Heat Treatment of Whey Protein/Lactose Mixtures Is Dependent on Glycation and Aggregation

    NARCIS (Netherlands)

    Liu, Fahui; Teodorowicz, Gosia; Wichers, Harry J.; Boekel, van Tiny; Hettinga, Kasper A.

    2016-01-01

    Heating of protein- and sugar-containing materials is considered the primary factor affecting the formation of advanced glycation end products (AGEs). This study aimed to investigate the influence of heating conditions, digestion, and aggregation on the binding capacity of AGEs to the soluble AGE

  1. Advanced calculus

    CERN Document Server

    Fitzpatrick, Patrick M

    2009-01-01

    Advanced Calculus is intended as a text for courses that furnish the backbone of the student's undergraduate education in mathematical analysis. The goal is to rigorously present the fundamental concepts within the context of illuminating examples and stimulating exercises. This book is self-contained and starts with the creation of basic tools using the completeness axiom. The continuity, differentiability, integrability, and power series representation properties of functions of a single variable are established. The next few chapters describe the topological and metric properties of Euclide

  2. Advanced calculus

    CERN Document Server

    Friedman, Avner

    2007-01-01

    This rigorous two-part treatment advances from functions of one variable to those of several variables. Intended for students who have already completed a one-year course in elementary calculus, it defers the introduction of functions of several variables for as long as possible, and adds clarity and simplicity by avoiding a mixture of heuristic and rigorous arguments.The first part explores functions of one variable, including numbers and sequences, continuous functions, differentiable functions, integration, and sequences and series of functions. The second part examines functions of several

  3. Advanced calculus

    CERN Document Server

    Widder, David V

    2012-01-01

    This classic text by a distinguished mathematician and former Professor of Mathematics at Harvard University, leads students familiar with elementary calculus into confronting and solving more theoretical problems of advanced calculus. In his preface to the first edition, Professor Widder also recommends various ways the book may be used as a text in both applied mathematics and engineering.Believing that clarity of exposition depends largely on precision of statement, the author has taken pains to state exactly what is to be proved in every case. Each section consists of definitions, theorem

  4. Advanced LIGO status

    International Nuclear Information System (INIS)

    Dwyer, S

    2015-01-01

    Advanced LIGO is currently in the final stages of installation and early commissioning. In the design of Advanced LIGO a key goal was the ability to detect gravitational waves from compact object binary inspirals, as these are thought to be the most likely candidates for early detections with ground based interferometers. Special emphasis has been placed on improving the low frequency sensitivity relative to the first generations of LIGO, in addition to improving the high frequency sensitivity by increasing the laser power. The interferometer in Livingston Louisiana has been locked (continuously held within the linear operating range) and noise investigations have begun, and the major installation activities for the interferometer at Hanford, Washington are completed. (paper)

  5. Steam generator management program

    International Nuclear Information System (INIS)

    Cho, Nam Cheoul; Kim, Moo Soo; Lee, Kwang Woo

    2003-01-01

    Recently, the common concern of nuclear power industry in the development of technology mitigating and preventing the aging of steam generator tubes prevails, because the trends of steam generator flaws at Uljin unit no. 1,2 and KSNP impose a burden on the operation of nuclear power plant. While the regulatory agency is demanding the establishment of the advanced general performance maintenance system, the steam generator management program adapting advanced technology is being developed which may comply with EPRI PWR SG guidelines based on NEI 97-06. General guidelines including all the maintenance aspects consist of the tube integrity assessment criteria, repair limit, allowable leakage level, water chemistry will be composed in order to obtain the approval of regulatory agency and be applied to nuclear power plant early 2005. This presentation is to introduce maintenance state including SG tube degradation and main contents of advanced SG management program being developed, and furthermore update present and future plan, and estimate the alternation after the completion

  6. Advances in Modal Logic

    DEFF Research Database (Denmark)

    Modal logic is a subject with ancient roots in the western logical tradition. Up until the last few generations, it was pursued mainly as a branch of philosophy. But in recent years, the subject has taken new directions with connections to topics in computer science and mathematics. This volume...... is the proceedings of the conference of record in its fi eld, Advances in Modal Logic. Its contributions are state-of-the-art papers. The topics include decidability and complexity results for specifi c modal logics, proof theory of modal logic, logics for reasoning about time and space, provability logic, dynamic...... epistemic logic, and the logic of evidence....

  7. Advanced Pacemaker

    Science.gov (United States)

    1990-01-01

    Synchrony, developed by St. Jude Medical's Cardiac Rhythm Management Division (formerly known as Pacesetter Systems, Inc.) is an advanced state-of-the-art implantable pacemaker that closely matches the natural rhythm of the heart. The companion element of the Synchrony Pacemaker System is the Programmer Analyzer APS-II which allows a doctor to reprogram and fine tune the pacemaker to each user's special requirements without surgery. The two-way communications capability that allows the physician to instruct and query the pacemaker is accomplished by bidirectional telemetry. APS-II features 28 pacing functions and thousands of programming combinations to accommodate diverse lifestyles. Microprocessor unit also records and stores pertinent patient data up to a year.

  8. Generative Semantics.

    Science.gov (United States)

    King, Margaret

    The first section of this paper deals with the attempts within the framework of transformational grammar to make semantics a systematic part of linguistic description, and outlines the characteristics of the generative semantics position. The second section takes a critical look at generative semantics in its later manifestations, and makes a case…

  9. Generative collectives

    NARCIS (Netherlands)

    van Osch, W.; Avital, M.; Sabherwal, R.; Sumner, M.

    2010-01-01

    Analyzing generative group activities against the backdrop of an increasingly connected world, this theory development paper introduces the concept of "generative collectives" as a new framework for classifying internet-based collectives and a novel theoretical lens for explaining why some

  10. Generational Phenomenology

    African Journals Online (AJOL)

    denise

    by Xers, and how Millennials not only accept but expect diversity (320 ff.). However, nothing is actually said to the effect that generational relations might be affected by the different styles of thinking, speaking, and values of women. Moreover, it seems likely that generations and their relations are different for people of color,.

  11. Sound generator

    NARCIS (Netherlands)

    Berkhoff, Arthur P.

    2008-01-01

    A sound generator, particularly a loudspeaker, configured to emit sound, comprising a rigid element (2) enclosing a plurality of air compartments (3), wherein the rigid element (2) has a back side (B) comprising apertures (4), and a front side (F) that is closed, wherein the generator is provided

  12. Sound generator

    NARCIS (Netherlands)

    Berkhoff, Arthur P.

    2010-01-01

    A sound generator, particularly a loudspeaker, configured to emit sound, comprising a rigid element (2) enclosing a plurality of air compartments (3), wherein the rigid element (2) has a back side (B) comprising apertures (4), and a front side (F) that is closed, wherein the generator is provided

  13. Pulse Generator

    Science.gov (United States)

    Greer, Lawrence (Inventor)

    2017-01-01

    An apparatus and a computer-implemented method for generating pulses synchronized to a rising edge of a tachometer signal from rotating machinery are disclosed. For example, in one embodiment, a pulse state machine may be configured to generate a plurality of pulses, and a period state machine may be configured to determine a period for each of the plurality of pulses.

  14. Sound generator

    NARCIS (Netherlands)

    Berkhoff, Arthur P.

    2007-01-01

    A sound generator, particularly a loudspeaker, configured to emit sound, comprising a rigid element (2) enclosing a plurality of air compartments (3), wherein the rigid element (2) has a back side (B) comprising apertures (4), and a front side (F) that is closed, wherein the generator is provided

  15. Generative Semantics

    Science.gov (United States)

    Bagha, Karim Nazari

    2011-01-01

    Generative semantics is (or perhaps was) a research program within linguistics, initiated by the work of George Lakoff, John R. Ross, Paul Postal and later McCawley. The approach developed out of transformational generative grammar in the mid 1960s, but stood largely in opposition to work by Noam Chomsky and his students. The nature and genesis of…

  16. Advances in luminescence instrument systems

    DEFF Research Database (Denmark)

    Bøtter-Jensen, L.; Bulur, E.; Duller, G.A.T.

    2000-01-01

    We report on recent advances in the development of luminescence measurement systems and techniques at Riso. These include: (1) optical stimulation units based on new-generation powerful blue light (470 nm) emitting diodes providing up to 28 mW/cm(2) for OSL measurements; (2) an infrared (830 nm...

  17. The Advanced LIGO photon calibrators.

    Science.gov (United States)

    Karki, S; Tuyenbayev, D; Kandhasamy, S; Abbott, B P; Abbott, T D; Anders, E H; Berliner, J; Betzwieser, J; Cahillane, C; Canete, L; Conley, C; Daveloza, H P; De Lillo, N; Gleason, J R; Goetz, E; Izumi, K; Kissel, J S; Mendell, G; Quetschke, V; Rodruck, M; Sachdev, S; Sadecki, T; Schwinberg, P B; Sottile, A; Wade, M; Weinstein, A J; West, M; Savage, R L

    2016-11-01

    The two interferometers of the Laser Interferometry Gravitational-wave Observatory (LIGO) recently detected gravitational waves from the mergers of binary black hole systems. Accurate calibration of the output of these detectors was crucial for the observation of these events and the extraction of parameters of the sources. The principal tools used to calibrate the responses of the second-generation (Advanced) LIGO detectors to gravitational waves are systems based on radiation pressure and referred to as photon calibrators. These systems, which were completely redesigned for Advanced LIGO, include several significant upgrades that enable them to meet the calibration requirements of second-generation gravitational wave detectors in the new era of gravitational-wave astronomy. We report on the design, implementation, and operation of these Advanced LIGO photon calibrators that are currently providing fiducial displacements on the order of 10 -18 m/Hz with accuracy and precision of better than 1%.

  18. The Advanced LIGO photon calibrators

    Science.gov (United States)

    Karki, S.; Tuyenbayev, D.; Kandhasamy, S.; Abbott, B. P.; Abbott, T. D.; Anders, E. H.; Berliner, J.; Betzwieser, J.; Cahillane, C.; Canete, L.; Conley, C.; Daveloza, H. P.; De Lillo, N.; Gleason, J. R.; Goetz, E.; Izumi, K.; Kissel, J. S.; Mendell, G.; Quetschke, V.; Rodruck, M.; Sachdev, S.; Sadecki, T.; Schwinberg, P. B.; Sottile, A.; Wade, M.; Weinstein, A. J.; West, M.; Savage, R. L.

    2016-11-01

    The two interferometers of the Laser Interferometry Gravitational-wave Observatory (LIGO) recently detected gravitational waves from the mergers of binary black hole systems. Accurate calibration of the output of these detectors was crucial for the observation of these events and the extraction of parameters of the sources. The principal tools used to calibrate the responses of the second-generation (Advanced) LIGO detectors to gravitational waves are systems based on radiation pressure and referred to as photon calibrators. These systems, which were completely redesigned for Advanced LIGO, include several significant upgrades that enable them to meet the calibration requirements of second-generation gravitational wave detectors in the new era of gravitational-wave astronomy. We report on the design, implementation, and operation of these Advanced LIGO photon calibrators that are currently providing fiducial displacements on the order of 1 0-18m /√{Hz } with accuracy and precision of better than 1%.

  19. Advanced Solid State Lighting for AES Deep Space Hab

    Data.gov (United States)

    National Aeronautics and Space Administration — The advanced Solid State Lighting (SSL) assemblies augmented 2nd generation modules under development for the Advanced Exploration Systems Deep Space Habitat in...

  20. Advanced light water reactor plant

    International Nuclear Information System (INIS)

    Giedraityte, Zivile

    2008-01-01

    For nuclear power to be competitive with the other methods of electrical power generation the economic performance should be significantly improved by increasing the time spent on line generating electricity relative to time spent off-line conducting maintenance and refueling. Maintenance includes planned actions (surveillances) and unplanned actions (corrective maintenance) to respond to component degradation or failure. A methodology is described which is used to resolve maintenance related operating cycle length barriers. Advanced light water nuclear power plant is designed with the purpose to maximize online generating time by increasing operating cycle length. (author)

  1. Flywheel Generator

    OpenAIRE

    Yuniarsih, Pratitis; Bachtiyar, Fahmi; Rosyidin, Mufti; Prabawanto, Trisakti

    2014-01-01

    Lately, the needs of energy is increasing but its availability is very limited. Therefore,it is important to do more research on energy reform. Generator is one of the alternative energy which commonly used by the public, but it has a minus value such as the voltage instability and low efficiency of the generator . Based on those issues,so we made an application flywheel in electrical generator, which aims to produce a concept of power efficiency increase, stabilize the output voltage of the ...

  2. Treatment-free interval as a metric of patient experience and a health outcome of value for advanced multiple myeloma: the case for the histone deacetylase inhibitor panobinostat, a next-generation novel agent.

    Science.gov (United States)

    Richardson, Paul; Roy, Anuja; Acharyya, Suddhasatta; Panneerselvam, Ashok; Mendelson, Estella; Günther, Andreas; Lonial, Sagar; Einsele, Hermann

    2017-10-01

    Patients with relapsed or relapsed/refractory multiple myeloma (RRMM) face poor treatment options by the time third-line therapy is required, despite advances in overall survival in recent years. Treatment free interval (TFI) and opportunities to maintain quality of life (QoL) have been cited as additional measures of efficacy that can be utilized in personalized treatment decisions. The clinical health outcomes data from PANORAMA-1, the pivotal phase-3 trial comparing panobinostat-bortezomib-dexamethasone (PAN-BTZ-DEX) with placebo (PBO)-BTZ-DEX in RRMM patients treated with 1 to 3 prior regimens, retrospectively assessed TFI as a health outcome measure and metric of patient treatment experience relevant to the RRMM population. PAN-BTZ-DEX shows promise for prolonged TFI (mean TFI, 7.49 months; 95% CI, 6.02 to 8.71) compared to PBO-BTZ-DEX (mean TFI, 3.86 months; 95% CI, 3.08 to 4.60) for heavily pre-treated advanced RRMM patients), due to the short duration of therapy and extended progression free-survival. Further, QoL during the TFI was similar to baseline. PAN-BTZ-DEX provides a treatment regimen with prolonged TFI benefits previously not available for RRMM patients. TFI has not been traditionally measured in clinical trials, but should be assessed in prospective data collection given its value to payers, providers, and patients.

  3. Advanced worker protection system

    International Nuclear Information System (INIS)

    Caldwell, B.; Duncan, P.; Myers, J.

    1995-01-01

    The Department of Energy (DOE) is in the process of defining the magnitude and diversity of Decontamination and Decommissioning (D ampersand D) obligations at its numerous sites. The DOE believes that existing technologies are inadequate to solve many challenging problems such as how to decontaminate structures and equipment cost effectively, what to do with materials and wastes generated, and how to adequately protect workers and the environment. Preliminary estimates show a tremendous need for effective use of resources over a relatively long period (over 30 years). Several technologies are being investigated which can potentially reduce D ampersand D costs while providing appropriate protection to DOE workers. The DOE recognizes that traditional methods used by the EPA in hazardous waste site clean up activities are insufficient to provide the needed protection and worker productivity demanded by DOE D ampersand D programs. As a consequence, new clothing and equipment which can adequately protect workers while providing increases in worker productivity are being sought for implementation at DOE sites. This project will result in the development of an Advanced Worker Protection System (AWPS). The AWPS will be built around a life support backpack that uses liquid air to provide cooling as well as breathing gas to the worker. The backpack will be combined with advanced protective garments, advanced liquid cooling garment, respirator, communications, and support equipment to provide improved worker protection, simplified system maintenance, and dramatically improve worker productivity through longer duration work cycles. Phase I of the project has resulted in a full scale prototype Advanced Worker Protection Ensemble (AWPE, everything the worker will wear), with sub-scale support equipment, suitable for integrated testing and preliminary evaluation. Phase II will culminate in a full scale, certified, pre-production AWPS and a site demonstration

  4. Technical Advances for the Clinical Genomic Evaluation of Sudden Cardiac Death: Verification of Next-Generation Sequencing Panels for Hereditary Cardiovascular Conditions Using Formalin-Fixed Paraffin-Embedded Tissues and Dried Blood Spots.

    Science.gov (United States)

    Baudhuin, Linnea M; Leduc, Charles; Train, Laura J; Avula, Rajeswari; Kluge, Michelle L; Kotzer, Katrina E; Lin, Peter T; Ackerman, Michael J; Maleszewski, Joseph J

    2017-12-01

    Postmortem genetic testing for heritable cardiovascular (CV) disorders is often lacking because ideal specimens (ie, whole blood) are not retained routinely at autopsy. Formalin-fixed paraffin-embedded tissue (FFPET) is ubiquitously collected at autopsy, but DNA quality hampers its use with traditional sequencing methods. Targeted next-generation sequencing may offer the ability to circumvent such limitations, but a method has not been previously described. The primary aim of this study was to develop and evaluate the use of FFPET for heritable CV disorders via next-generation sequencing. Nineteen FFPET (heart) and blood (whole blood or dried blood spot) specimens underwent targeted next-generation sequencing using a custom panel of 101 CV-associated genes. Nucleic acid yield and quality metrics were evaluated in relation to FFPET specimen age (6 months to 15 years; n=14) and specimen type (FFPET versus whole blood and dried blood spot; n=12). Four FFPET cases with a clinical phenotype of heritable CV disorder were analyzed. Accuracy and precision were 100% concordant between all sample types, with read depths >100× for most regions tested. Lower read depth, as low as 40×, was occasionally observed with FFPET and dried blood spot. High-quality DNA was obtained from FFPET samples as old as 15 years. Genomic analysis of FFPET from the 4 phenotype-positive/genotype unknown cases all revealed putative disease-causing variants. Similar performance characteristics were observed for next-generation sequencing of FFPET, whole blood, and dried blood spot in the evaluation of inherited CV disorders. Although blood is preferable for genetic analyses, this study offers an alternative when only FFPET is available. © 2017 American Heart Association, Inc.

  5. 30 years of squeezed light generation

    DEFF Research Database (Denmark)

    Andersen, Ulrik Lund; Gehring, Tobias; Marquardt, Christoph

    2016-01-01

    Squeezed light generation has come of age. Significant advances on squeezed light generation have been made over the last 30 years—from the initial, conceptual experiment in 1985 till today’s top-tuned, application-oriented setups. Here we review the main experimental platforms for generating...... quadrature squeezed light that have been investigated in the last 30 years....

  6. Advanced Production Planning Models

    Energy Technology Data Exchange (ETDEWEB)

    JONES,DEAN A.; LAWTON,CRAIG R.; KJELDGAARD,EDWIN A.; WRIGHT,STEPHEN TROY; TURNQUIST,MARK A.; NOZICK,LINDA K.; LIST,GEORGE F.

    2000-12-01

    >This report describes the innovative modeling approach developed as a result of a 3-year Laboratory Directed Research and Development project. The overall goal of this project was to provide an effective suite of solvers for advanced production planning at facilities in the nuclear weapons complex (NWC). We focused our development activities on problems related to operations at the DOE's Pantex Plant. These types of scheduling problems appear in many contexts other than Pantex--both within the NWC (e.g., Neutron Generators) and in other commercial manufacturing settings. We successfully developed an innovative and effective solution strategy for these types of problems. We have tested this approach on actual data from Pantex, and from Org. 14000 (Neutron Generator production). This report focuses on the mathematical representation of the modeling approach and presents three representative studies using Pantex data. Results associated with the Neutron Generator facility will be published in a subsequent SAND report. The approach to task-based scheduling described here represents a significant addition to the literature for large-scale, realistic scheduling problems in a variety of production settings.

  7. PULSE GENERATOR

    Science.gov (United States)

    Roeschke, C.W.

    1957-09-24

    An improvement in pulse generators is described by which there are produced pulses of a duration from about 1 to 10 microseconds with a truly flat top and extremely rapid rise and fall. The pulses are produced by triggering from a separate input or by modifying the current to operate as a free-running pulse generator. In its broad aspect, the disclosed pulse generator comprises a first tube with an anode capacitor and grid circuit which controls the firing; a second tube series connected in the cathode circuit of the first tube such that discharge of the first tube places a voltage across it as the leading edge of the desired pulse; and an integrator circuit from the plate across the grid of the second tube to control the discharge time of the second tube, determining the pulse length.

  8. Advanced LIGO: sources and astrophysics

    International Nuclear Information System (INIS)

    Creighton, Teviet

    2003-01-01

    Second-generation detectors in LIGO will take us from the discovery phase of gravitational-wave observations to the phase of true gravitational-wave astrophysics, with hundreds or thousands of potential sources. This paper surveys the most likely and interesting potential sources for Advanced LIGO, and the astrophysical processes that each one will probe. I conclude that binary inspiral signals are expected, while continuous signals from pulsars are plausible but not guaranteed. Other sources, such as core-collapse bursts, cosmic strings and primordial stochastic backgrounds, are speculative sources for Advanced LIGO, but also potentially the most interesting, since they push the limits of our theoretical knowledge

  9. Fiscal 1993 achievement report on next-generation industrial structure technology (Advanced materials for extreme environments - Development of methane fueled aeroengine); 1993 nendo chotaikankyosei senshin zairyo no kenkyu kaihatsu seika hokokusho. Methane nenryo kokukiyo engine no kaihatsu

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1994-03-01

    Efforts were exerted to develop advanced materials for use under extreme environments, which were intermetallic compounds and fiber reinforced intermetallic compound composite materials excellent in heat resistance, specific strength, oxidation resistance, or the like. For the development of intermetallic compounds, efforts were made to develop Ti-Al-X (X=metal) high specific strength intermetallic compounds and Nb-Al-X (X=metal) high melting point intermetallic compounds. Ternary phase diagrams were prepared and the effect of added elements on basic characteristics was investigated. Basics of element technologies (texture control, melting, casting, and isothermal rolling) for manufacturing panel materials were studied and, in the case of Ti-Al-X systems, Ti-Al thin panels were fabricated. In the case of Nb-Al-X systems, items were experimentally fabricated by casting in an effort to study precision casting technology optimization. For the development of composite materials, efforts were made to develop SiC based and SiMC (M=metal) based fibers, and studies were carried out to complex them with Ti-Al based matrices. (NEDO)

  10. [Emigrate or not? How would the next Spanish generation of physicians decide? A study on emigration-related reasons and motivations of advanced medical students in 11 Universities in Spain].

    Science.gov (United States)

    Bernardini-Zambrini, Diego; Barengo, Noel; Bardach, Ariel; Hanna, Mina; Núñez, Juan Macias

    2011-05-01

    To explore intentions, motivations and country preferences related with professional emigration in a sample of advanced medical students. Cross sectional and descriptive study. 11 Universities in Spain. A total of 740 students in their two final courses. The survey used a self administered questionnaire asking about plans to emigrate, preferred destination countries and reasons for wishing to work abroad. A total of 740 valid questionnaires were collected, 711 (96%) from Spanish students and 26 (4%) from foreigner students. A preference to move abroad was indicated by 375 (51%) students, the most popular destinations being United Kingdom, USA, Canada and Portugal. The answers were classified using categories from "very important" to "not important". As a "very important" reason, "To work in a better health care system" was chosen by 276 students, "To continue with my medical education and training" by 160, "To work in an environment that allows me to progress" by 269, and "To earn a better salary" by 243 students. The study illustrates various motivational factors which of why medical students wish to move abroad in search of better professional conditions. The use of appropriate interventions could modify these attitudes. This study could be a starting point for exploring and analyzing the conditions of undergraduate medical students in Spain as a key to address the problem of medical emigration. Copyright © 2009 Elsevier España, S.L. All rights reserved.

  11. Generation Next

    Science.gov (United States)

    Hawkins, B. Denise

    2010-01-01

    There is a shortage of accounting professors with Ph.D.s who can prepare the next generation. To help reverse the faculty deficit, the American Institute of Certified Public Accountants (CPAs) has created the new Accounting Doctoral Scholars program by pooling more than $17 million and soliciting commitments from more than 70 of the nation's…

  12. Generative Contexts

    Science.gov (United States)

    Lyles, Dan Allen

    Educational research has identified how science, technology, engineering, and mathematics (STEM) practice and education have underperforming metrics in racial and gender diversity, despite decades of intervention. These disparities are part of the construction of a culture of science that is alienating to these populations. Recent studies in a social science framework described as "Generative Justice" have suggested that the context of social and scientific practice might be modified to bring about more just and equitable relations among the disenfranchised by circulating the value they and their non-human allies create back to them in unalienated forms. What is not known are the underlying principles of social and material space that makes a system more or less generative. I employ an autoethnographic method at four sites: a high school science class; a farm committed to "Black and Brown liberation"; a summer program geared towards youth environmental mapping; and a summer workshop for Harlem middle school students. My findings suggest that by identifying instances where material affinity, participatory voice, and creative solidarity are mutually reinforcing, it is possible to create educational contexts that generate unalienated value, and circulate it back to the producers themselves. This cycle of generation may help explain how to create systems of justice that strengthen and grow themselves through successive iterations. The problem of lack of diversity in STEM may be addressed not merely by recruiting the best and the brightest from underrepresented populations, but by changing the context of STEM education to provide tools for its own systematic restructuring.

  13. Buildings for advanced technology

    CERN Document Server

    Teague, E; Murday, James

    2015-01-01

    This book deals with the design and construction of buildings for nanoscale science and engineering research. The information provided in this book is useful for designing and constructing buildings for such advanced technologies as nanotechnology, nanoelectronics and biotechnology. The book outlines the technology challenges unique to each of the building environmental challenges outlined below and provides best practices and examples of engineering approaches to address them: • Establishing and maintaining critical environments: temperature, humidity, and pressure • Structural vibration isolation • Airborne vibration isolation (acoustic noise) • Isolation of mechanical equipment-generated vibration/acoustic noise • Cost-effective power conditioning • Grounding facilities for low electrical interference • Electromagnetic interference (EMI)/Radio frequency interference (RFI) isolation • Airborne particulate contamination • Airborne organic and chemical contamination • Environment, safety a...

  14. Advances in lung ultrasound

    International Nuclear Information System (INIS)

    Francisco Neto, Miguel Jose; Rahal Junior, Antonio; Vieira, Fabio Augusto Cardillo; Silva, Paulo Savoia Dias da; Funari, Marcelo Buarque de Gusmao

    2016-01-01

    Ultrasound examination of the chest has advanced in recent decades. This imaging modality is currently used to diagnose several pathological conditions and provides qualitative and quantitative information. Acoustic barriers represented by the aerated lungs and the bony framework of the chest generate well-described sonographic artifacts that can be used as diagnostic aids. The normal pleural line and A, B, C, E and Z lines (also known as false B lines) are artifacts with specific characteristics. Lung consolidation and pneumothorax sonographic patterns are also well established. Some scanning protocols have been used in patient management. The Blue, FALLS and C.A.U.S.E. protocols are examples of algorithms using artifact combinations to achieve accurate diagnoses. Combined chest ultrasonography and radiography are often sufficient to diagnose and manage lung and chest wall conditions. Chest ultrasonography is a highly valuable diagnostic tool for radiologists, emergency and intensive care physicians. (author)

  15. The advanced photon source

    International Nuclear Information System (INIS)

    Galayda, J.N.

    1995-01-01

    The Advanced Photon Source (APS) is a 7-GeV third-generation synchrotron radiation storage ring and full-energy positron injector. Construction project funding began in 1989, and ground breaking took place on 5 May 1990. Construction of all accelerator facilities was completed in January 1995 and storage ring commissioning is underway. First observation of x-rays from a bending magnet source took place on 26 March 1995. Nearly all performance specifications of the injector have been reached, and first observations indicate that the reliability, dynamic aperture, emittance, and orbit stability in the storage ring are satisfactory. Observation of radiation from the first of 20 insertion device beamlines is scheduled for October 1995. Start of regular operations is expected to take place well before the APS Project target date of December 1996

  16. ADVANCED TURBINE SYSTEMS PROGRAM

    Energy Technology Data Exchange (ETDEWEB)

    Sy Ali

    2002-03-01

    The market for power generation equipment is undergoing a tremendous transformation. The traditional electric utility industry is restructuring, promising new opportunities and challenges for all facilities to meet their demands for electric and thermal energy. Now more than ever, facilities have a host of options to choose from, including new distributed generation (DG) technologies that are entering the market as well as existing DG options that are improving in cost and performance. The market is beginning to recognize that some of these users have needs beyond traditional grid-based power. Together, these changes are motivating commercial and industrial facilities to re-evaluate their current mix of energy services. One of the emerging generating options is a new breed of advanced fuel cells. While there are a variety of fuel cell technologies being developed, the solid oxide fuel cells (SOFC) and molten carbonate fuel cells (MCFC) are especially promising, with their electric efficiency expected around 50-60 percent and their ability to generate either hot water or high quality steam. In addition, they both have the attractive characteristics of all fuel cells--relatively small siting footprint, rapid response to changing loads, very low emissions, quiet operation, and an inherently modular design lending itself to capacity expansion at predictable unit cost with reasonably short lead times. The objectives of this project are to:(1) Estimate the market potential for high efficiency fuel cell hybrids in the U.S.;(2) Segment market size by commercial, industrial, and other key markets;(3) Identify and evaluate potential early adopters; and(4) Develop results that will help prioritize and target future R&D investments. The study focuses on high efficiency MCFC- and SOFC-based hybrids and competing systems such as gas turbines, reciprocating engines, fuel cells and traditional grid service. Specific regions in the country have been identified where these

  17. Inflow Turbulence Generation Methods

    Science.gov (United States)

    Wu, Xiaohua

    2017-01-01

    Research activities on inflow turbulence generation methods have been vigorous over the past quarter century, accompanying advances in eddy-resolving computations of spatially developing turbulent flows with direct numerical simulation, large-eddy simulation (LES), and hybrid Reynolds-averaged Navier-Stokes-LES. The weak recycling method, rooted in scaling arguments on the canonical incompressible boundary layer, has been applied to supersonic boundary layer, rough surface boundary layer, and microscale urban canopy LES coupled with mesoscale numerical weather forecasting. Synthetic methods, originating from analytical approximation to homogeneous isotropic turbulence, have branched out into several robust methods, including the synthetic random Fourier method, synthetic digital filtering method, synthetic coherent eddy method, and synthetic volume forcing method. This article reviews major progress in inflow turbulence generation methods with an emphasis on fundamental ideas, key milestones, representative applications, and critical issues. Directions for future research in the field are also highlighted.

  18. ADVANCED SULFUR CONTROL CONCEPTS

    Energy Technology Data Exchange (ETDEWEB)

    Apostolos A. Nikolopoulos; Santosh K. Gangwal; William J. McMichael; Jeffrey W. Portzer

    2003-01-01

    Conventional sulfur removal in integrated gasification combined cycle (IGCC) power plants involves numerous steps: COS (carbonyl sulfide) hydrolysis, amine scrubbing/regeneration, Claus process, and tail-gas treatment. Advanced sulfur removal in IGCC systems involves typically the use of zinc oxide-based sorbents. The sulfides sorbent is regenerated using dilute air to produce a dilute SO{sub 2} (sulfur dioxide) tail gas. Under previous contracts the highly effective first generation Direct Sulfur Recovery Process (DSRP) for catalytic reduction of this SO{sub 2} tail gas to elemental sulfur was developed. This process is currently undergoing field-testing. In this project, advanced concepts were evaluated to reduce the number of unit operations in sulfur removal and recovery. Substantial effort was directed towards developing sorbents that could be directly regenerated to elemental sulfur in an Advanced Hot Gas Process (AHGP). Development of this process has been described in detail in Appendices A-F. RTI began the development of the Single-step Sulfur Recovery Process (SSRP) to eliminate the use of sorbents and multiple reactors in sulfur removal and recovery. This process showed promising preliminary results and thus further process development of AHGP was abandoned in favor of SSRP. The SSRP is a direct Claus process that consists of injecting SO{sub 2} directly into the quenched coal gas from a coal gasifier, and reacting the H{sub 2}S-SO{sub 2} mixture over a selective catalyst to both remove and recover sulfur in a single step. The process is conducted at gasifier pressure and 125 to 160 C. The proposed commercial embodiment of the SSRP involves a liquid phase of molten sulfur with dispersed catalyst in a slurry bubble-column reactor (SBCR).

  19. Cluster generator

    Science.gov (United States)

    Donchev, Todor I [Urbana, IL; Petrov, Ivan G [Champaign, IL

    2011-05-31

    Described herein is an apparatus and a method for producing atom clusters based on a gas discharge within a hollow cathode. The hollow cathode includes one or more walls. The one or more walls define a sputtering chamber within the hollow cathode and include a material to be sputtered. A hollow anode is positioned at an end of the sputtering chamber, and atom clusters are formed when a gas discharge is generated between the hollow anode and the hollow cathode.

  20. Life Support Systems: Oxygen Generation and Recovery

    Data.gov (United States)

    National Aeronautics and Space Administration — The Advanced Exploration Systems (AES) Life Support Systems project Oxygen Generation and Recovery technology development area encompasses several sub-tasks in an...

  1. On-Site Renewable Energy Generation

    Science.gov (United States)

    This guide describes a variety of approaches that local governments can use to advance climate and energy goals by meeting some or all of their electricity needs through on-site renewable energy generation.

  2. ADVANCED TURBINE SYSTEMS PROGRAM

    Energy Technology Data Exchange (ETDEWEB)

    Gregory Gaul

    2004-04-21

    Natural gas combustion turbines are rapidly becoming the primary technology of choice for generating electricity. At least half of the new generating capacity added in the US over the next twenty years will be combustion turbine systems. The Department of Energy has cosponsored with Siemens Westinghouse, a program to maintain the technology lead in gas turbine systems. The very ambitious eight year program was designed to demonstrate a highly efficient and commercially acceptable power plant, with the ability to fire a wide range of fuels. The main goal of the Advanced Turbine Systems (ATS) Program was to develop ultra-high efficiency, environmentally superior and cost effective competitive gas turbine systems for base load application in utility, independent power producer and industrial markets. Performance targets were focused on natural gas as a fuel and included: System efficiency that exceeds 60% (lower heating value basis); Less than 10 ppmv NO{sub x} emissions without the use of post combustion controls; Busbar electricity that are less than 10% of state of the art systems; Reliability-Availability-Maintainability (RAM) equivalent to current systems; Water consumption minimized to levels consistent with cost and efficiency goals; and Commercial systems by the year 2000. In a parallel effort, the program was to focus on adapting the ATS engine to coal-derived or biomass fuels. In Phase 1 of the ATS Program, preliminary investigators on different gas turbine cycles demonstrated that net plant LHV based efficiency greater than 60% was achievable. In Phase 2 the more promising cycles were evaluated in greater detail and the closed-loop steam-cooled combined cycle was selected for development because it offered the best solution with least risk for achieving the ATS Program goals for plant efficiency, emissions, cost of electricity and RAM. Phase 2 also involved conceptual ATS engine and plant design and technology developments in aerodynamics, sealing

  3. Achievement report for fiscal 1996 on the research and development of micromachine technology. Development of advanced-function maintenance technology for power generation facilities; 1996 nendo micromachine gijutsu no kenkyu kaihatsu seika hokokusho. Hatsuden shisetsuyo kokino maintenance gijutsu kaihatsu

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-03-01

    Technologies for integrating functions are studied for a self-propelled surroundings recognition system that travels in a small-diameter tube at power generation facilities. Parameters are analyzed, and piezoelectric locomotion devices are reduced in size. A disk shape microantenna is experimentally built and evaluated, which is for realizing energy supply and communication by means of microwaves. Studies are conducted to improve the performance of optical energy transmission devices and to realize their systematization. Basic specifications are established for the embodiment of CCD (charge coupled device) microcameras to be installed. A high-efficiency, high-reliability micromachine system is constructed, in which multiple machines coordinate with each other for the exterior inspection of groups of small-diameter tubes. Devices which are capable of driving, deceleration, and propulsion prove to be feasible. Basic specifications are established for microconnectors to connect, separate, and combine multiple machines as occasion calls. Also discussed is the development of a micromachine for tube interior check and repair which operates making use of the inspection hole enabling tube interior check and repair without the need of disassembling the equipment to be repaired.

  4. Magnet Free Generators - 3rd Generation Wind Turbine Generators

    DEFF Research Database (Denmark)

    Jensen, Bogi Bech; Mijatovic, Nenad; Henriksen, Matthew Lee

    2013-01-01

    This paper presents an introduction to superconducting wind turbine generators, which are often referred to as 3rd generation wind turbine generators. Advantages and challenges of superconducting generators are presented with particular focus on possible weight and efficiency improvements. A comp....... A comparison of the rare earth usage in different topologies of permanent magnet generators and superconducting generators is also presented....

  5. Renewable energies for power generation

    International Nuclear Information System (INIS)

    Freris, L.; Infield, D.

    2009-01-01

    Power generation from renewable energy sources is different from power generation from classical energies (nuclear, thermal..). Therefore, the integration into the grid of the electricity supplied by renewable sources requires a deep thinking. The reason is that these power sources are controlled by variable elements, like wind, water and sun, which condition production. This book deals with the following aspects in detail: characteristics of classical and intermittent generators; grid balancing between supply and demand; conversion methods of renewable energies into electricity; power systems; privatizing of power generation and birth of new markets, in particular the 'green' power market; development of renewable energies thanks to technical advances. It gives a comprehensive overview of the present day available renewable energy sources for power generation. (J.S.)

  6. Power generation

    International Nuclear Information System (INIS)

    Nunez, Anibal D.

    2001-01-01

    In the second half of twentieth century, nuclear power became an industrial reality. Now the operating 433 power plants, the 37 plants under construction, near 9000 years/reactor with only one serious accident with emission of radioactive material to the environment (Chernobyl) show the maturity of this technology. Today nuclear power contribute a 17% to the global generation and an increase of 75 % of the demand of electricity is estimated for 2020 while this demand is expected to triplicate by 2050. How this requirement can be satisfied? All the indicators seems to demonstrate that nuclear power will be the solution because of the shortage of other sources, the increase of the prices of the non renewable fuels and the scarce contribution of the renewable ones. In addition, the climatic changes produced by the greenhouse effect make even more attractive nuclear power. The situation of Argentina is analyzed and compared with other countries. The convenience of an increase of nuclear power contribution to the total national generation seems clear and the conclusion of the construction of the Atucha II nuclear power plant is recommended

  7. Ohio Advanced Energy Manufacturing Center

    Energy Technology Data Exchange (ETDEWEB)

    Kimberly Gibson; Mark Norfolk

    2012-07-30

    overall industry health. To aid the overall advanced energy industry, EWI developed and launched an Ohio chapter of the non-profit Advanced Energy Economy. In this venture, Ohio joins with six other states including Colorado, Connecticut, Illinois, Maine, Massachusetts, New Hampshire, Rhode Island and Vermont to help promote technologies that deliver energy that is affordable, abundant and secure. In a more specific arena, EWI's advanced energy group collaborated with the EWI-run Nuclear Fabrication Consortium to promote the nuclear supply chain. Through this project EWI has helped bring the supply chain up to date for the upcoming period of construction, and assisted them in understanding the demands for the next generation of facilities now being designed. In a more targeted manner, EWI worked with 115 individual advanced energy companies that are attempting to bring new technology to market. First, these interactions helped EWI develop an awareness of issues common to companies in different advanced energy sectors. By identifying and addressing common issues, EWI helps companies bring technology to market sooner and at a lower cost. These visits also helped EWI develop a picture of industry capability. This helped EWI provide companies with contacts that can supply commercial solutions to their new product development challenges. By providing assistance in developing supply chain partnerships, EWI helped companies bring their technology to market faster and at a lower cost than they might have been able to do by themselves. Finally, at the most granular level EWI performed dedicated research and development on new manufacturing processes for advanced energy. During discussions with companies participating in advanced energy markets, several technology issues that cut across market segments were identified. To address some of these issues, three crosscutting technology development projects were initiated and completed with Center support. This included reversible

  8. Alternative energy and distributed generation: thinking generations ahead

    International Nuclear Information System (INIS)

    Hunt, P.D.

    2001-01-01

    Alternative Energy will be discussed in the context of Distributed Generation, which is defined as a delivery platform for micro-power generation, close to the end-users, that can also supplement regional electricity grids. Many references in the paper pertain to Alberta. This is for two reasons: First, familiarity by the author, and more importantly, Alberta is the first region in Canada that has de-regulated it's electricity sector. De-regulation allows independent and smaller power generators to enter the market. Focussing on Alberta, with some references to other Canadian provinces and USA, electricity consumption trends will be reviewed and the pressures to decentralize electricity generation discussed. Re-structuring of the electricity sector, convergence of power generation and natural gas industries, advances in technologies, and environmental concerns are collectively contributing to the creation of a new business called 'Distributed Generation'. Efficiency benefits of combined heat and power associated with the more prominent emerging distributed generation technologies like micro-turbines and fuel cells, will be highlighted. Areas of research, development and demonstration that will enable the successful deployment of Distributed Generation will be suggested with respect to Generation Technologies, Systems Controls, Supporting Infrastructure, and Socio-Political Barriers. Estimates of investments in the various alternative energy technologies will be presented. Using current trends and emerging technologies the Paper will conclude with some predictions of future scenarios. (author)

  9. Idea generation

    DEFF Research Database (Denmark)

    Tollestrup, Christian H. T.; Laursen, Linda Nhu

    2015-01-01

    . Using a straight proposal creation process is expected to create proposals that operate within the present sociocultural meaning. Whereas an approach seeking ambiguity and discrepancy in the initial ideation sparks a deeper sense-making process, which in return creates proposals that can be interpreted...... as having new sociocultural meaning in line with Vergantis definition of radical innovation. This paper discusses the results of an experiment with 32 students on idea generation and product concept development. The experiment was setup as and A-B comparison between two set of students with the same...... objective: designing a new coffee machine for a specific brand, but one group was asked to seek ambiguity and dissonance before creating proposals. Results indicate a very clear difference in the outcome in terms of radical changes in relation to. Group A produced 12 out of 16 proposals in the Styling...

  10. Next generation DNA led technologies

    CERN Document Server

    Jyothsna, G; Kashyap, Amita

    2016-01-01

    This brief highlights advances in DNA technologies and their wider applications. DNA is the source of life and has been studied since a generation, but very little is known as yet. Several sophisticated technologies of the current era have laid their foundations on the principle of DNA based mechanisms. DNA based technologies are bringing a new revolution of Advanced Science and Technology. Forensic Investigation, Medical Diagnosis, Paternity Disputes, Individual Identity, Health insurance, Motor Insurance have incorporated the DNA testing and profiling technologies for settling the issues.

  11. Nuclear Thermal Propulsion for Advanced Space Exploration

    Science.gov (United States)

    Houts, M. G.; Borowski, S. K.; George, J. A.; Kim, T.; Emrich, W. J.; Hickman, R. R.; Broadway, J. W.; Gerrish, H. P.; Adams, R. B.

    2012-01-01

    The fundamental capability of Nuclear Thermal Propulsion (NTP) is game changing for space exploration. A first generation Nuclear Cryogenic Propulsion Stage (NCPS) based on NTP could provide high thrust at a specific impulse above 900 s, roughly double that of state of the art chemical engines. Characteristics of fission and NTP indicate that useful first generation systems will provide a foundation for future systems with extremely high performance. The role of the NCPS in the development of advanced nuclear propulsion systems could be analogous to the role of the DC-3 in the development of advanced aviation. Progress made under the NCPS project could help enable both advanced NTP and advanced Nuclear Electric Propulsion (NEP).

  12. Make Learning Matter for the Multitasking Generation

    Science.gov (United States)

    Adams, Jill

    2012-01-01

    Technological advances have created amazing opportunities for people throughout the world to access and share information. These opportunities have helped to create a generation of young adolescents who want to make the most of each minute of the day, seizing opportunities to seek information and communicate at the same time. This generation is…

  13. Plasma generator

    International Nuclear Information System (INIS)

    Omichi, Takeo; Yamanaka, Toshiyuki.

    1976-01-01

    Object: To recycle a coolant in a sealed hollow portion formed interiorly of a plasma limiter itself to thereby to cause direct contact between the coolant and the plasma limiter and increase of contact area therebetween to cool the plasma limiter. Structure: The heat resulting from plasma generated during operation and applied to the body of the plasma limiter is transmitted to the coolant, which recycles through an inlet and outlet pipe, an inlet and outlet nozzle and a hollow portion to hold the plasma limiter at a level less than a predetermined temperature. On the other hand, the heater wire is, at the time of emergency operation, energized to heat the plasma limiter, but this heat is transmitted to the limiter body to increase the temperature thereof. However, the coolant recycling the hollow portion comes into direct contact with the limiter body, and since the plasma limiter surround the hollow portion, the heat amount transmitted from the limiter body to the coolant increases to sufficiently cool the plasma limiter. (Yoshihara, H.)

  14. Advanced Radio Resource Management for IMT

    DEFF Research Database (Denmark)

    Monserrat, Jose M.; Sroka, Pawel; Auer, Gunther

    generation mobile, 4G. This paper presents the first set of innovative concepts for advanced Radio Resource Management that has been identified by the Innovation Group of WINNER+ for potential inclusion in IMT-Advanced. These concepts consist of promising innovative techniques that are ready to be included...... in current OFDMAbased cellular systems to enhance system performance. A brief description of each technique together with the relevant state of the art is provided....

  15. Nanoscale Advances in Catalysis and Energy Applications

    Energy Technology Data Exchange (ETDEWEB)

    Li, Yimin; Somorjai, Gabor A.

    2010-05-12

    In this perspective, we present an overview of nanoscience applications in catalysis, energy conversion, and energy conservation technologies. We discuss how novel physical and chemical properties of nanomaterials can be applied and engineered to meet the advanced material requirements in the new generation of chemical and energy conversion devices. We highlight some of the latest advances in these nanotechnologies and provide an outlook at the major challenges for further developments.

  16. Advances in laser solenoid fusion reactor design

    International Nuclear Information System (INIS)

    Steinhauer, L.C.; Quimby, D.C.

    1978-01-01

    The laser solenoid is an alternate fusion concept based on a laser-heated magnetically-confined plasma column. The reactor concept has evolved in several systems studies over the last five years. We describe recent advances in the plasma physics and technology of laser-plasma coupling. The technology advances include progress on first walls, inner magnet design, confinement module design, and reactor maintenance. We also describe a new generation of laser solenoid fusion and fusion-fission reactor designs

  17. Improved trip generation data for Texas using workplace and special generator surveys : workshop materials.

    Science.gov (United States)

    2014-08-01

    Workshop Objectives: : Present Texas Trip Generation Manual : How developed : How it can be used, built upon : Provide examples and discuss : Present Generic WP Attraction Rates : Review Trip Attractions and Advanced Models

  18. Next generation breeding.

    Science.gov (United States)

    Barabaschi, Delfina; Tondelli, Alessandro; Desiderio, Francesca; Volante, Andrea; Vaccino, Patrizia; Valè, Giampiero; Cattivelli, Luigi

    2016-01-01

    The genomic revolution of the past decade has greatly improved our understanding of the genetic make-up of living organisms. The sequencing of crop genomes has completely changed our vision and interpretation of genome organization and evolution. Re-sequencing allows the identification of an unlimited number of markers as well as the analysis of germplasm allelic diversity based on allele mining approaches. High throughput marker technologies coupled with advanced phenotyping platforms provide new opportunities for discovering marker-trait associations which can sustain genomic-assisted breeding. The availability of genome sequencing information is enabling genome editing (site-specific mutagenesis), to obtain gene sequences desired by breeders. This review illustrates how next generation sequencing-derived information can be used to tailor genomic tools for different breeders' needs to revolutionize crop improvement. Copyright © 2015 Elsevier Ireland Ltd. All rights reserved.

  19. Advance Directives - Multiple Languages

    Science.gov (United States)

    ... Expand Section Advance Directives - 简体中文 (Chinese, Simplified (Mandarin dialect)) Bilingual PDF Health Information Translations Chinese, Traditional (Cantonese dialect) (繁體中文) Expand Section Advance ...

  20. Advances in light water reactor technologies

    CERN Document Server

    Saito, Takehiko; Ishiwatari, Yuki; Oka, Yoshiaki

    2010-01-01

    ""Advances in Light Water Reactor Technologies"" focuses on the design and analysis of advanced nuclear power reactors. This volume provides readers with thorough descriptions of the general characteristics of various advanced light water reactors currently being developed worldwide. Safety, design, development and maintenance of these reactors is the main focus, with key technologies like full MOX core design, next-generation digital I&C systems and seismic design and evaluation described at length. This book is ideal for researchers and engineers working in nuclear power that are interested

  1. Power generation, operation, and control

    CERN Document Server

    Wood, Allen J

    2012-01-01

    A comprehensive text on the operation and control of power generation and transmission systems In the ten years since Allen J. Wood and Bruce F. Wollenberg presented their comprehensive introduction to the engineering and economic factors involved in operating and controlling power generation systems in electric utilities, the electric power industry has undergone unprecedented change. Deregulation, open access to transmission systems, and the birth of independent power producers have altered the structure of the industry, while technological advances have created a host of new opportunities

  2. Advanced worker protection system

    International Nuclear Information System (INIS)

    Caldwell, B.; Duncan, P.; Myers, J.

    1995-01-01

    The Department of Energy (DOE) is in the process of defining the magnitude and diversity of Decontamination and Decommissioning (D ampersand D) obligations at its numerous sites. The DOE believes that existing technologies are inadequate to solve many challenging problems such as how to decontaminate structures and equipment cost effectively, what to do with materials and wastes generated, and how to adequately protect workers and the environment. Preliminary estimates show a tremendous need for effective use of resources over a relatively long period (over 30 years). Several technologies are being investigated which can potentially reduce D ampersand D costs while providing appropriate protection to DOE workers. The DOE recognizes that traditional methods used by the EPA in hazardous waste site clean up activities are insufficient to provide the needed protection and worker productivity demanded by DOE D ampersand D programs. As a consequence, new clothing and equipment which can adequately protect workers while providing increases in worker productivity are being sought for implementation at DOE sites. This project describes the development of an Advanced Worker Protection System (AWPS) which will include a life-support backpack with liquid air for cooling and as a supply of breathing gas, protective clothing, respirators, communications, and support equipment

  3. Steam generators of PWRs and plan of replacing steam generators

    International Nuclear Information System (INIS)

    Dodo, Takashi; Matsushita, Kiyohiko.

    1995-01-01

    Also in Japan, the plan of replacing steam generators which are one of most important equipments of PWRs is being advanced. In this report, the whole circumstances of the plan of replacing steam generators, such as the background that necessitated the replacement, the concrete plan of the replacement, the results of the replacement in foreign countries and others, are described in general. The function of steam generators is to form a part of the pressure boundary for confining reactor primary coolant, and to generate steam by the heat exchange between primary and secondary coolants. The basic structure is a shell and tube type heat exchanger having vertically installed, inverse U shape tubes, in which primary coolant flows. In Japan as of December, 1994, 22 PWR plants of 18,186 million kW output were in operation. The management of steam generators and the background of their replacement due to the fear of public about heating tube leak, the enormous cost of the inspection and repair, the restriction of power system operation and others are explained. As for the steam generators of Takahama No. 2, Oi No. 1 and Genkai No. 1 plants, the application for the replacement was made, and the breakdown of a tube occurred in Mihama No. 2 plant. The replacement of steam generators in Japan and foreign countries is reported. (K.I.)

  4. Knowing Generation Y: a new generation of nurses in practice.

    Science.gov (United States)

    Chung, Stephanie M

    Generation Y is commonly defined as those people born between 1980 and 2000, now aged in their 20s and 30s. Their grandparents experienced post-World War II reconstruction, their parents the economic boom of the 1980s. There are currently 81 million individuals in the Generation Y cohort in the USA, making it the second-largest, and possibly most influential, cohort since World War II (Manion, 2009). Members of Generation Y are diverse, technologically advanced and vocal about their opinions. They tend to resist traditional hierarchy, want recognition/reward for achievements and distrust institutions. Knowing these characteristics is useful for nurse managers, preceptors and team members working with members of Generation Y. Studies have proven that Generation Y is challenging the nursing workforce through rapid turnover (Cogin, 2012). This article explores a theoretical model that predicts retention and/or turnover of nurses in light of Generation Y behaviours and motivators-for example, moving from agency to agency rather than devoting many years to a single practice. Further research is needed to find out whether these behaviours and motivators are unique to Generation Y alone.

  5. Recent Advances in Second Generation Ethanol Production by Thermophilic Bacteria

    OpenAIRE

    Sean Michael Scully; Johann Orlygsson

    2014-01-01

    There is an increased interest in using thermophilic bacteria for the production of bioethanol from complex lignocellulosic biomass due to their higher operating temperatures and broad substrate range. This review focuses upon the main genera of thermophilic anaerobes known to produce ethanol, their physiology, and the relevance of various environmental factors on ethanol yields including the partial pressure of hydrogen, ethanol tolerance, pH and substrate inhibition. Additionally, recent de...

  6. EXT-II: a second generation advanced ac propulsion system

    Energy Technology Data Exchange (ETDEWEB)

    Bates, B.; Patil, P.B.; Ciccarelli, M.F.

    1986-01-01

    This paper discusses the characteristics of the concept and includes discussion of the system constraints, including traction battery constraints, and brief descriptions of the major subsystems being developed. The components discussed include: the system controller, dc to ac inverter, an internal permanent magnet ac motor and a two-speed automatic transmission with an integral final drive and differential. The motor and transmission are on a common axis and are integrated into one compact unit that is integral with the rear axle of the vehicle.

  7. Advances in the generation of a new emulsified fuel

    Energy Technology Data Exchange (ETDEWEB)

    Chavez, A. [Technical Consultancy, Energy Plus UC, Huitzilac, Morelos (Mexico); Ramirez, M. [Instituto Mexicano del Petroleo, Programa de Aseguramiento de Hidrocarburos, Mexico, D.F. (Mexico); Medina, E. [Universidad Nacional Autonoma de Mexico, Departamento de Termofluidos, Facultad de Ingenieria, Mexico, D.F. (Mexico); Bolado, R.; Mora, J. [Instituto Mexicano del Petroleo, Laboratorio de Combustion, Veracruz (Mexico)

    2011-08-15

    The development of a new emulsified fuel is described, from the conceptual idea to the semi-industrial tests of the final product. The starting point was the necessity to lower the particulate matter (PM) emissions produced by the combustion of more than 200 MBD of heavy fuel oil (HFO) used for electric power conversion. The major component of HFO is a vacuum residue of the oil refining process mixed with light cycle oils to make it pumpable. An alternative to handle and burn the high viscosity residue (solid at room temperature) is by converting it in an oil-in-water emulsion. The best emulsions resulted of 70% residue in 30% water, Sauter Mean Diameter of 10-20 {mu}m and a stability of more than 90 days. Spray burning tests of the emulsion against HFO in a semi-industrial 500 kW furnace showed a reduction in PM emissions of 24-36%. (orig.)

  8. Electrospun nanofibers: New generation materials for advanced applications

    International Nuclear Information System (INIS)

    Thenmozhi, S.; Dharmaraj, N.; Kadirvelu, K.; Kim, Hak Yong

    2017-01-01

    Highlights: • A review covering important aspects of electrospinning technique is presented. • Applications of nanofibers in various fields are reviewed. • Possibility to up-scale electrospinning technique to industry also included. - Abstract: Electrospinning (E-spin) is a unique technique to fabricate polymeric as well as metal oxide nanofibers. Research on electrospun nanofibers is a very active field in material science owing to their novel applications in diverse domains. The main focus of this review is to provide an insight into E-spin technique by understanding the working principle, influencing parameters and applications of nanofibers in different walks of life. Several hundreds of papers are published on the preparation, modification and applications of nanofibers produced by E-spin technique in the areas like sensor development, decontamination, energy storage, biomedical and catalysis etc. Details on the industrial scale development of E-spin technique, current scenario and future developments are also covered in this review.

  9. From first generation biofuels to advanced solar biofuels.

    Science.gov (United States)

    Aro, Eva-Mari

    2016-01-01

    Roadmaps towards sustainable bioeconomy, including the production of biofuels, in many EU countries mostly rely on biomass use. However, although biomass is renewable, the efficiency of biomass production is too low to be able to fully replace the fossil fuels. The use of land for fuel production also introduces ethical problems in increasing the food price. Harvesting solar energy by the photosynthetic machinery of plants and autotrophic microorganisms is the basis for all biomass production. This paper describes current challenges and possibilities to sustainably increase the biomass production and highlights future technologies to further enhance biofuel production directly from sunlight. The biggest scientific breakthroughs are expected to rely on a new technology called "synthetic biology", which makes engineering of biological systems possible. It will enable direct conversion of solar energy to a fuel from inexhaustible raw materials: sun light, water and CO2. In the future, such solar biofuels are expected to be produced in engineered photosynthetic microorganisms or in completely synthetic living factories.

  10. Computer Image Generation: Advanced Visual/Sensor Simulation.

    Science.gov (United States)

    1981-10-01

    levels of suboivision. 3. The cubic surface may not be appropriate for all surfaces. Flat surfaces may be rendered with slight undulations oue to aujacent...aimensions. The alternative is to present cultural objects at a subpixel level, w nicn is simpler but not as cepenoaole because suopixei-size objects wiii...34 Doctoral dissertation, University of Utah, December 1978. Carpenter, L.G., "Computer Rendering of Fractal Curves and Surfaces," Siggraph 󈨔, Special

  11. Smart mobile in-vehicle systems next generation advancements

    CERN Document Server

    Abut, Huseyin; Takeda, Kazuya; Hansen, John

    2014-01-01

    This is an edited collection by world-class experts, from diverse fields, focusing on integrating smart in-vehicle systems with human factors to enhance safety in automobiles. The book presents developments on road safety, in-vehicle technologies and state-of-the art systems. Includes coverage of DSP technologies in adaptive automobiles, algorithms and evaluation of in-car communication systems, driver-status monitoring and stress detection, in-vehicle dialogue systems and human-machine interfaces, challenges in video and audio processing for in-vehicle products, multi-sensor fusion for driver identification and vehicle to infrastructure wireless technologies.

  12. Advanced Low Temperature Thermoelectric Materials for Cryogenic Power Generation

    Data.gov (United States)

    National Aeronautics and Space Administration — The current state of the art thermoelectric materials for low temperatures for the past 50 years have been alloys based upon Bi2Te3 with ZT of 1.2 at 300 K.  These...

  13. Advanced Material Intelligent Processing Center: Next Generation Scalable Lean Manufacturing

    Science.gov (United States)

    2012-09-04

    Additional Modules: UV cure, spray on bagging Figure 35: Various process modules that slide into the AMP chassis . Figure 36: Robotic reach and...tape. The ultrasonic transducer is mounted on a z-axis linear guide to allow the knife to retract while material is fed to the surface. The entire...is shown in Figure 41. All feedback and control data is fed to and from a PC workstation through a National Instruments PXI chassis . This chassis

  14. Advanced relay technologies in next generation wireless communications

    CERN Document Server

    Krikidis, Ioannis

    2016-01-01

    This book details the use of the cooperative networks/relaying approach in new and emerging telecommunications technologies such as full-duplex radio, massive multiple-input multiple-output (MIMO), network coding and spatial modulation, and new application areas including visible light communications (VLC), wireless power transfer, and 5G.

  15. Electrospun nanofibers: New generation materials for advanced applications

    Energy Technology Data Exchange (ETDEWEB)

    Thenmozhi, S. [Inorganic & Nanomaterials Research Laboratory, Department of Chemistry, Bharathiar University, Coimbatore 641 046 (India); DRDO-BU CLS, Bharathiar University Campus, Coimbatore 641 046 (India); Dharmaraj, N., E-mail: dharmaraj@buc.edu.in [Inorganic & Nanomaterials Research Laboratory, Department of Chemistry, Bharathiar University, Coimbatore 641 046 (India); Kadirvelu, K. [DRDO-BU CLS, Bharathiar University Campus, Coimbatore 641 046 (India); Kim, Hak Yong [Department of Textile Engineering, Chonbuk National University, Chonju 561-756 (Korea, Republic of)

    2017-03-15

    Highlights: • A review covering important aspects of electrospinning technique is presented. • Applications of nanofibers in various fields are reviewed. • Possibility to up-scale electrospinning technique to industry also included. - Abstract: Electrospinning (E-spin) is a unique technique to fabricate polymeric as well as metal oxide nanofibers. Research on electrospun nanofibers is a very active field in material science owing to their novel applications in diverse domains. The main focus of this review is to provide an insight into E-spin technique by understanding the working principle, influencing parameters and applications of nanofibers in different walks of life. Several hundreds of papers are published on the preparation, modification and applications of nanofibers produced by E-spin technique in the areas like sensor development, decontamination, energy storage, biomedical and catalysis etc. Details on the industrial scale development of E-spin technique, current scenario and future developments are also covered in this review.

  16. Advanced Computer Image Generation Techniques Exploiting Perceptual Characteristics

    Science.gov (United States)

    1981-08-01

    to least: red, yellow , white, blue. If refractive correction is made to allow for sharp focusing with blue illumi- nation, highest acuities are found...because blue fields are found to behave differently than red or yellow fields. CIG Implications: Relevant data for the development of dynamic range...end. To provide more visual structure, lengths of floral wallpaper were hung on portions of the walls and ceiling. Two light- bulbs illuminated the

  17. Advances in fluidized bed technologies

    International Nuclear Information System (INIS)

    Mutanen, K.

    1992-01-01

    Atmospheric fluidized bed combustion (AFBC) has advanced into industrial cogeneration and utility-scale electric generation. During the 1980's AFBC became the dominant technology in the United States for power generation systems fired with solid fuels. Development of pressurized fluidized bed combustion/gasification (PFB/G) has grown rapidly from small bench-scale rigs to large pilot and demonstration plants. AFBC as large as 160 MWe in capacity are now in operation, while pressurized combustion systems generating 80 MWe have started up two years ago. The major driving forces behind development of fluidized bed technologies are all the time strictening emission control regulations, need for fuel flexibility, repowering of older power plants and need for higher efficiency in electricity generation. Independent power producers (IPP) and cogenerators were the first ones in the United States who accepted AFBC for wide commercial use. Their role will be dominant in the markets of the 1990's also. Developers of AFBC systems are working on designs that reduce investment costs, decrease emissions and offer even higher reliability and availability in utility-scale applications while developers of PFBC/G work on designs that increase plant efficiencies, allow modular construction, decrease emissions further and reduce the cost of generating power. This paper presents technological background, commercial status, boiler performance, emissions and future developments for both AFBC and PFBC/G systems

  18. Advances in chemical physics

    CERN Document Server

    Rice, Stuart A

    2011-01-01

    The Advances in Chemical Physics series-the cutting edge of research in chemical physics The Advances in Chemical Physics series provides the chemical physics and physical chemistry fields with a forum for critical, authoritative evaluations of advances in every area of the discipline. Filled with cutting-edge research reported in a cohesive manner not found elsewhere in the literature, each volume of the Advances in Chemical Physics series offers contributions from internationally renowned chemists and serves as the perfect supplement to any advanced graduate class devoted to the study of che

  19. Advances in chemical Physics

    CERN Document Server

    Rice, Stuart A

    2011-01-01

    The Advances in Chemical Physics series-the cutting edge of research in chemical physics The Advances in Chemical Physics series provides the chemical physics and physical chemistry fields with a forum for critical, authoritative evaluations of advances in every area of the discipline. Filled with cutting-edge research reported in a cohesive manner not found elsewhere in the literature, each volume of the Advances in Chemical Physics series offers contributions from internationally renowned chemists and serves as the perfect supplement to any advanced graduate class devoted to the study of che

  20. ACR-700 advanced technologies

    International Nuclear Information System (INIS)

    Tapping, R.L.; Turner, C.W.; Yu, S.K.W.; Olmstead, R.; Speranzini, R.A.

    2004-01-01

    A successful advanced reactor plant will have optimized economics including reduced operating and maintenance costs, improved performance, and enhanced safety. Incorporating improvements based on advanced technologies ensures cost, safety and operational competitiveness of the ACR-700. These advanced technologies include modern configuration management; construction technologies; operational technology for the control centre and information systems for plant monitoring and analysis. This paper summarizes the advanced technologies used to achieve construction and operational improvements to enhance plant economic competitiveness, advances in the operational technology used for reactor control, and presents the development of the Smart CANDU suite of tools and its application to existing operating reactors and to the ACR-700. (author)

  1. Advances in chemical physics

    CERN Document Server

    Rice, Stuart A

    2012-01-01

    The Advances in Chemical Physics series-the cutting edge of research in chemical physics The Advances in Chemical Physics series provides the chemical physics field with a forum for critical, authoritative evaluations of advances in every area of the discipline. Filled with cutting-edge research reported in a cohesive manner not found elsewhere in the literature, each volume of the Advances in Chemical Physics series serves as the perfect supplement to any advanced graduate class devoted to the study of chemical physics. This volume explores: Quantum Dynamical Resonances in Ch

  2. Trip generation characteristics of special generators

    Science.gov (United States)

    2010-03-01

    Special generators are introduced in the sequential four-step modeling procedure to represent certain types of facilities whose trip generation characteristics are not fully captured by the standard trip generation module. They are also used in the t...

  3. Next generation CANDU plants

    International Nuclear Information System (INIS)

    Hedges, K.R.; Yu, S.K.W.

    1998-01-01

    Future CANDU designs will continue to meet the emerging design and performance requirements expected by the operating utilities. The next generation CANDU products will integrate new technologies into both the product features as well as into the engineering and construction work processes associated with delivering the products. The timely incorporation of advanced design features is the approach adopted for the development of the next generation of CANDU. AECL's current products consist of 700MW Class CANDU 6 and 900 MW Class CANDU 9. Evolutionary improvements are continuing with our CANDU products to enhance their adaptability to meet customers ever increasing need for higher output. Our key product drivers are for improved safety, environmental protection and improved cost effectiveness. Towards these goals we have made excellent progress in Research and Development and our investments are continuing in areas such as fuel channels and passive safety. Our long term focus is utilizing the fuel cycle flexibility of CANDU reactors as part of the long term energy mix

  4. Future nuclear power generation

    International Nuclear Information System (INIS)

    Mosbah, D.S.; Nasreddine, M.

    2006-01-01

    The book includes an introduction then it speaks about the options to secure sources of energy, nuclear power option, nuclear plants to generate energy including light-water reactors (LWR), heavy-water reactors (HWR), advanced gas-cooled reactors (AGR), fast breeder reactors (FBR), development in the manufacture of reactors, fuel, uranium in the world, current status of nuclear power generation, economics of nuclear power, nuclear power and the environment and nuclear power in the Arab world. A conclusion at the end of the book suggests the increasing demand for energy in the industrialized countries and in a number of countries that enjoy special and economic growth such as China and India pushes the world to search for different energy sources to insure the urgent need for current and anticipated demand in the near and long-term future in light of pessimistic and optimistic outlook for energy in the future. This means that states do a scientific and objective analysis of the currently available data for the springboard to future plans to secure the energy required to support economy and welfare insurance.

  5. Advanced materials for clean energy

    CERN Document Server

    Xu (Kyo Jo), Qiang

    2015-01-01

    Arylamine-Based Photosensitizing Metal Complexes for Dye-Sensitized Solar CellsCheuk-Lam Ho and Wai-Yeung Wongp-Type Small Electron-Donating Molecules for Organic Heterojunction Solar CellsZhijun Ning and He TianInorganic Materials for Solar Cell ApplicationsYasutake ToyoshimaDevelopment of Thermoelectric Technology from Materials to GeneratorsRyoji Funahashi, Chunlei Wan, Feng Dang, Hiroaki Anno, Ryosuke O. Suzuki, Takeyuki Fujisaka, and Kunihito KoumotoPiezoelectric Materials for Energy HarvestingDeepam Maurya, Yongke Yan, and Shashank PriyaAdvanced Electrode Materials for Electrochemical Ca

  6. Survey of Advanced Acceleration Techniques

    CERN Document Server

    Joshi, C J

    2004-01-01

    In this talk I will review the recent progress on the production, manipulation, transport, acceleration and focusing of relativistic electron beams using advanced techniques. In particular, I will report recent progress on cathode-less electron injectors, IFEL bunchers and accelerators, plasma accelerating and transport structures, and electron and positron beam focusing using plasmas. The plasma structures for acceleration can be excited either by laser beams or charged-particle beams. The acceleration gradients in either case can be enormous. For unmatched beams the betatron radiation loss, as the beam oscillates transversely in the high gradient accelerating structure, can generate a high brightness x-ray beam. These x-rays can, in turn, be used to generate positrons. Work done by different groups around the world will be reviewed.

  7. Self generation, small generation, and embedded generation issues

    International Nuclear Information System (INIS)

    2001-01-01

    The New Brunswick Market Design Committee for electric power restructuring has been directed to examine issues regarding cogeneration and small-scale, on-site generation and how they will fit within the framework of the bilateral contract market. The Committee will also have to deal with issues of generation embedded in a distribution system. The Committee has defined cogeneration as the simultaneous production of electricity and useful thermal energy. Self-generation has been defined as small-scale power generation by an end-user, while embedded generation has been defined as a generation facility that is located within a distribution utility but is not directly connected to the transmission system. The Committee has postponed its decision on whether embedded generation will be eligible to participate under the bilateral contract market for electricity. This report discusses general issues such as the physical support of generation, market support of generation, transition issues and policy issues. It also discusses generation support issues such as operating reserves, transmission tariff issues, and distribution tariffs. Market support issues such as transmission access for generation sales were also considered, along with market access for generation sales, and net metering for behind the meter generation. 7 refs., 1 tab

  8. The next generation CANDU 6

    International Nuclear Information System (INIS)

    Hopwood, J.M.

    1999-01-01

    AECL's product line of CANDU 6 and CANDU 9 nuclear power plants are adapted to respond to changing market conditions, experience feedback and technological development by a continuous improvement process of design evolution. The CANDU 6 Nuclear Power Plant design is a successful family of nuclear units, with the first four units entering service in 1983, and the most recent entering service this year. A further four CANDU 6 units are under construction. Starting in 1996, a focused forward-looking development program is under way at AECL to incorporate a series of individual improvements and integrate them into the CANDU 6, leading to the evolutionary development of the next-generation enhanced CANDU 6. The CANDU 6 improvements program includes all aspects of an NPP project, including engineering tools improvements, design for improved constructability, scheduling for faster, more streamlined commissioning, and improved operating performance. This enhanced CANDU 6 product will combine the benefits of design provenness (drawing on the more than 70 reactor-years experience of the seven operating CANDU 6 units), with the advantages of an evolutionary next-generation design. Features of the enhanced CANDU 6 design include: Advanced Human Machine Interface - built around the Advanced CANDU Control Centre; Advanced fuel design - using the newly demonstrated CANFLEX fuel bundle; Improved Efficiency based on improved utilization of waste heat; Streamlined System Design - including simplifications to improve performance and safety system reliability; Advanced Engineering Tools, -- featuring linked electronic databases from 3D CADDS, equipment specification and material management; Advanced Construction Techniques - based on open top equipment installation and the use of small skid mounted modules; Options defined for Passive Heat Sink capability and low-enrichment core optimization. (author)

  9. Research and development project in fiscal 1990 for large industrial technologies. Achievement report on research and development of ultra-advanced processing systems (Development of high-level processing devices for electric power generation facility members); 1990 nendo chosentan kako system no kenkyu kaihatsu seika hokokusho. Hatsuden shisetsuyo buzai kodo kako sochi kaihatsu

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1991-03-01

    Research and development has been performed with an objective to establish the processing technology using excitation beam required for the advanced technology industries, and the ultra-precision machining technology to realize the nano-technology. This paper summarizes the achievements in fiscal 1990. In the research on the large output and long life technology for excimer laser, an average output of 500 W or more was demonstrated achieving the intermediate target by developing and improving the technologies for low electric power gas circulation, high efficiency discharge and excitation, and large output oscillation control. In the research on intensity resistant optical element technology, a prototype device was fabricated to create and process axially symmetrical aspherical shapes, whereas SiC aspherical shape creation and processing were demonstrated at the shape accuracy of three microns or better, and surface roughness of 20 nanometers or less, having achieved the intermediate target. Regarding the large current ion beam, a demonstration device was completed based on improvements and test results on the sheet plasma generator. In the research and development of the high-level processing technology, low-temperature forming technology was developed for oxide ceramic thin films by using the excimer laser abrasion method. (NEDO)

  10. Rapid medical advances challenge the tooling industry.

    Science.gov (United States)

    Conley, B

    2008-01-01

    The requirement for greater performance in smaller spaces has increased demands for product and process innovation in tubing and other medical products. In turn, these developments have placed greater demands on the producers of the advanced tooling for these products. Tooling manufacturers must now continuously design equipment with much tighter tolerances for more sophisticated coextrusions and for newer generations of multilumen and multilayer tubing.

  11. Reliability of the Advanced REACH Tool (ART)

    NARCIS (Netherlands)

    Schinkel, J.; Fransman, W.; McDonnell, P.E.; Entink, R.K.; Tielemans, E.; Kromhout, H.

    2014-01-01

    Objectives: The aim of this study was to assess the reliability of the Advanced REACH Tool (ART) by (i) studying interassessor agreement of the resulting exposure estimates generated by the ART mechanistic model, (ii) studying interassessor agreement per model parameters of the ART mechanistic

  12. Gestures and Insight in Advanced Mathematical Thinking

    Science.gov (United States)

    Yoon, Caroline; Thomas, Michael O. J.; Dreyfus, Tommy

    2011-01-01

    What role do gestures play in advanced mathematical thinking? We argue that the role of gestures goes beyond merely communicating thought and supporting understanding--in some cases, gestures can help generate new mathematical insights. Gestures feature prominently in a case study of two participants working on a sequence of calculus activities.…

  13. Synthetic biology advances for pharmaceutical production

    Science.gov (United States)

    Breitling, Rainer; Takano, Eriko

    2015-01-01

    Synthetic biology enables a new generation of microbial engineering for the biotechnological production of pharmaceuticals and other high-value chemicals. This review presents an overview of recent advances in the field, describing new computational and experimental tools for the discovery, optimization and production of bioactive molecules, and outlining progress towards the application of these tools to pharmaceutical production systems. PMID:25744872

  14. Advances in rapid prototyping

    Energy Technology Data Exchange (ETDEWEB)

    Atwood, C.L.; McCarty, G.D.; Pardo, B.T.; Bryce, E.A.

    1993-12-31

    Recent advances in stereolithography and selective laser sintering have had a significant impact on the overall quality of parts produced using these rapid prototyping processes. The development and implementation of 3D System`s QuickCast{trademark} resin and software for building investment casting patterns have proven to be major steps toward fabricating highly accurate patterns with very good surface finishes. Sandia uses patterns generated from rapid prototyping processes to reduce the cycle time and cost of fabricating prototype parts in support of a Sandia National Laboratories managed program called FASTCAST. As participants in the Beta test program for QuickCast{trademark} resin and software, they experienced a steep learning curve and were able to build accurate parts in a short period of time. It is now possible, using this technology, to produce highly accurate prototype parts as well as acceptable firs article and small lots size production parts. They use the Selective Laser Sintering (SLS) process to fabricate prototype wax patterns for investment casting. DTM Corporation recently introduced the use of their polycarbonate material for fabricating investment casting patterns. The polycarbonate material is processed significantly faster, with improved strength, dimensional stability, and without a support structure during the build process. Sandia is currently changing from investment casting wax to polycarbonate for the fabrication of investment casting patterns using the SLS process. This presentation will focus on the successes with these new materials from the standpoints of application, accuracy, surface finish, and post processing. Also presented will be examples of parts manufactured by these processes.

  15. Towards advanced code simulators

    International Nuclear Information System (INIS)

    Scriven, A.H.

    1990-01-01

    The Central Electricity Generating Board (CEGB) uses advanced thermohydraulic codes extensively to support PWR safety analyses. A system has been developed to allow fully interactive execution of any code with graphical simulation of the operator desk and mimic display. The system operates in a virtual machine environment, with the thermohydraulic code executing in one virtual machine, communicating via interrupts with any number of other virtual machines each running other programs and graphics drivers. The driver code itself does not have to be modified from its normal batch form. Shortly following the release of RELAP5 MOD1 in IBM compatible form in 1983, this code was used as the driver for this system. When RELAP5 MOD2 became available, it was adopted with no changes needed in the basic system. Overall the system has been used for some 5 years for the analysis of LOBI tests, full scale plant studies and for simple what-if studies. For gaining rapid understanding of system dependencies it has proved invaluable. The graphical mimic system, being independent of the driver code, has also been used with other codes to study core rewetting, to replay results obtained from batch jobs on a CRAY2 computer system and to display suitably processed experimental results from the LOBI facility to aid interpretation. For the above work real-time execution was not necessary. Current work now centers on implementing the RELAP 5 code on a true parallel architecture machine. Marconi Simulation have been contracted to investigate the feasibility of using upwards of 100 processors, each capable of a peak of 30 MIPS to run a highly detailed RELAP5 model in real time, complete with specially written 3D core neutronics and balance of plant models. This paper describes the experience of using RELAP5 as an analyzer/simulator, and outlines the proposed methods and problems associated with parallel execution of RELAP5

  16. Advanced Control of Wheeled Inverted Pendulum Systems

    CERN Document Server

    Li, Zhijun; Fan, Liping

    2013-01-01

    Advanced Control of Wheeled Inverted Pendulum Systems is an orderly presentation of recent ideas for overcoming the complications inherent in the control of wheeled inverted pendulum (WIP) systems, in the presence of uncertain dynamics, nonholonomic kinematic constraints as well as underactuated configurations. The text leads the reader in a theoretical exploration of problems in kinematics,dynamics modeling, advanced control design techniques,and trajectory generation for WIPs. An important concern is how to deal with various uncertainties associated with the nominal model, WIPs being characterized by unstable balance and unmodelled dynamics and being subject to time-varying external disturbances for which accurate models are hard to come by.   The book is self-contained, supplying the reader with everything from mathematical preliminaries and the basic Lagrange-Euler-based derivation of dynamics equations to various advanced motion control and force control approaches as well as trajectory generation met...

  17. Advances in Applied Mechanics

    OpenAIRE

    2013-01-01

    Advances in Applied Mechanics draws together recent significant advances in various topics in applied mechanics. Published since 1948, Advances in Applied Mechanics aims to provide authoritative review articles on topics in the mechanical sciences, primarily of interest to scientists and engineers working in the various branches of mechanics, but also of interest to the many who use the results of investigations in mechanics in various application areas, such as aerospace, chemical, civil, en...

  18. Steps to Advanced CANDU 600

    International Nuclear Information System (INIS)

    Oh, Yongshick; Brooks, G. L.

    1988-01-01

    The CANDU nuclear power system was developed from merging of AECL heavy water reactor technology with Ontario Hydro electrical power station expertise. The original four units of Ontario Hydro's Pickering Generating Station are the first full-scale commercial application of the CANDU system. AECL and Ontario Hydro then moved to the next evolutionary step, a more advanced larger scale design for four units at the Bruce Generating Station. CANDU 600 followed as a single unit nuclear electric power station design derived from an amalgam of features of the multiple unit Pickering and Bruce designs. The design of the CANDU 600 nuclear steam supply system is based on the Pickering design with improvements derived from the Bruce design. For example, most CANDU 600 auxiliary systems are based on Bruce systems, whereas the fuel handling system is based on the Pickering system. Four CANDU 600 units are in operation, and five are under construction in Romania. For the additional four units at Pickering Generating Station 'B', Ontario Hydro selected a replica of the Pickering 'A' design with limited design changes to maintain a high level of standardization across all eight units. Ontario Hydro applied a similar policy for the additional four units at Bruce Generating Station 'B'. For the four unit Darlington station, Ontario Hydro selected a design based on Bruce with improvements derived from operating experience, the CANDU 600 design and development programs

  19. Advanced Photon Source (APS)

    Data.gov (United States)

    Federal Laboratory Consortium — The Advanced Photon Source (APS) at the U.S. Department of Energy's Argonne National Laboratoryprovides this nation's (in fact, this hemisphere's) brightest storage...

  20. Advanced Simulation Center

    Data.gov (United States)

    Federal Laboratory Consortium — The Advanced Simulation Center consists of 10 individual facilities which provide missile and submunition hardware-in-the-loop simulation capabilities. The following...

  1. Next Generation Wind Turbine

    Energy Technology Data Exchange (ETDEWEB)

    Cheraghi, S. Hossein [Western New England Univ., Springfield, MA (United States); Madden, Frank [FloDesign Wind Turbine Corp., Waltham, MA (United States)

    2012-09-01

    The goal of this collaborative effort between Western New England University's College of Engineering and FloDesign Wind Turbine (FDWT) Corporation to wok on a novel areodynamic concept that could potentially lead to the next generation of wind turbines. Analytical studies and early scale model tests of FDWT's Mixer/Ejector Wind Turbine (MEWT) concept, which exploits jet-age advanced fluid dynamics, indicate that the concept has the potential to significantly reduce the cost of electricity over conventional Horizontal Axis Wind Turbines while reducing land usage. This project involved the design, fabrication, and wind tunnel testing of components of MEWT to provide the research and engineering data necessary to validate the design iterations and optimize system performance. Based on these tests, a scale model prototype called Briza was designed, fabricated, installed and tested on a portable tower to investigate and improve the design system in real world conditions. The results of these scale prototype efforts were very promising and have contributed significantly to FDWT's ongoing development of a product scale wind turbine for deployment in multiple locations around the U.S. This research was mutually beneficial to Western New England University, FDWT, and the DOE by utilizing over 30 student interns and a number of faculty in all efforts. It brought real-world wind turbine experience into the classroom to further enhance the Green Engineering Program at WNEU. It also provided on-the-job training to many students, improving their future employment opportunities, while also providing valuable information to further advance FDWT's mixer-ejector wind turbine technology, creating opportunities for future project innovation and job creation.

  2. Integrated Multi-Team Decision Making Processes and Effectiveness and the Connecticut Center for Advanced Technology

    National Research Council Canada - National Science Library

    Mathieu, John

    2004-01-01

    .... This program established a three part implementation path: First, the Advanced Technology Center will focus on key issues in propulsion and advanced power systems as well as take a leadership role in Next Generation Manufacturing technology...

  3. Reliability assurance for regulation of advanced reactors

    International Nuclear Information System (INIS)

    Fullwood, R.; Lofaro, R.; Samanta, P.

    1992-01-01

    The advanced nuclear power plants must achieve higher levels of safety than the first generation of plants. Showing that this is indeed true provides new challenges to reliability and risk assessment methods in the analysis of the designs employing passive and semi-passive protection. Reliability assurance of the advanced reactor systems is important for determining the safety of the design and for determining the plant operability. Safety is the primary concern, but operability is considered indicative of good and safe operation. this paper discusses several concerns for reliability assurance of the advanced design encompassing reliability determination, level of detail required in advanced reactor submittals, data for reliability assurance, systems interactions and common cause effects, passive component reliability, PRA-based configuration control system, and inspection, training, maintenance and test requirements. Suggested approaches are provided for addressing each of these topics

  4. Advanced Sensors for Safety and Security

    CERN Document Server

    Khudaverdyan, Surik

    2013-01-01

    This book results from a NATO Advanced Research Workshop titled “Technological Innovations in CBRNE Sensing and Detection for Safety, Security, and Sustainability” held in Yerevan, Armenia in 2012. The objective was to discuss and exchange views as to how fusion of advanced technologies can lead to improved sensors/detectors in support of defense, security, and situational awareness. The chapters range from policy and implementation, advanced sensor platforms using stand-off (THz and optical) and point-contact methods for detection of chemical, nuclear, biological, nuclear and explosive agents and contaminants in water, to synthesis methods for several materials used for sensors.  In view of asymmetric, kinetic, and distributed nature of threat vectors, an emphasis is placed to examine new generation of sensors/detectors that utilize an ecosystems of innovation and advanced sciences convergence in support of effective counter-measures against  CBRNE threats. The book will be of considerable interest and...

  5. Reliability assurance for regulation of advanced reactors

    International Nuclear Information System (INIS)

    Fullwood, R.; Lofaro, R.; Samanta, P.

    1991-01-01

    The advanced nuclear power plants must achieve higher levels of safety than the first generation of plants. Showing that this is indeed true provides new challenges to reliability and risk assessment methods in the analysis of the designs employing passive and semi-passive protection. Reliability assurance of the advanced reactor systems is important for determining the safety of the design and for determining the plant operability. Safety is the primary concern, but operability is considered indicative of good and safe operation. This paper discusses several concerns for reliability assurance of the advanced design encompassing reliability determination, level of detail required in advanced reactor submittals, data for reliability assurance, systems interactions and common cause effects, passive component reliability, PRA-based configuration control system, and inspection, training, maintenance and test requirements. Suggested approaches are provided for addressing each of these topics

  6. Leading Generation Y

    National Research Council Canada - National Science Library

    Newman, Jill M

    2008-01-01

    .... Whether referred to as the Millennial Generation, Generation Y or the Next Generation, the Army needs to consider the gap between Boomers, Generation X and the Soldiers that fill our junior ranks...

  7. Holistic High-Fidelity Modeling Strategy for Advanced Composites

    Data.gov (United States)

    National Aeronautics and Space Administration — Engineering demands of current and next generation aerospace vehicles dictate the use of state-of-the-art materials. Advanced Fiber-Reinforced Polymer Composites...

  8. Advancing Sustainable Materials Management: Facts and Figures Report

    Science.gov (United States)

    Each year EPA releases the Advancing Sustainable Materials Management: Facts and Figures report, formerly called Municipal Solid Waste in the United States: Facts and Figures. It includes information on Municipal Solid Waste generation, recycling, an

  9. Advanced Pumped Storage Hydropower and Ancillary Services Provision

    Energy Technology Data Exchange (ETDEWEB)

    Muljadi, Eduard; Gevorgian, Vahan; Mohanpurkar, Manish; Luo, Yusheng; Hovsapian, Rob; Koritarov, Vladimir

    2017-07-12

    This paper presents a high-level overview of the capability of advanced pumped storage hydropower to provide ancillary services including frequency regulation and oscillation damping. Type 3 and Type 4 generators are discussed. The examples given are for a small power system that uses a diesel generator as the main generator and a very large system that uses a gas turbine as the main generator.

  10. Advances in dental materials.

    Science.gov (United States)

    Fleming, Garry J P

    2014-05-01

    The dental market is replete with new resorative materials marketed on the basis of novel technological advances in materials chemistry, bonding capability or reduced operator time and/or technique sensitivity. This paper aims to consider advances in current materials, with an emphasis on their role in supporting contemporary clinical practice.

  11. Advanced research technology transfer

    International Nuclear Information System (INIS)

    Naraghi, Masud

    1977-01-01

    The importance of advanced research in the less developed countries of the world is described. Advanced research is a way of building from the top; it helps industrial development; it provides ''know-how'' economically; it enhances international understanding; it prevents the brain drain to developed countries and is of mutual benefit. The problems concerned with this type of research are pointed out

  12. How valid are future generations' arguments for preserving wilderness?

    Science.gov (United States)

    Thomas A. More; James R. Averill; Thomas H. Stevens

    2000-01-01

    We are often urged to preserve wilderness for the sake of future generations. Future generations consist of potential persons who are mute stakeholders in the decisions of today. Many claims about the rights of future generations or our present obligations to them have been vigorously advanced and just as vigorously denied. Recent theorists, however, have argued for a...

  13. User Multiplexing in Relay Enhanced LTE-Advanced Networks

    DEFF Research Database (Denmark)

    Teyeb, Oumer Mohammed; Frederiksen, Frank; Redana, Simone

    2010-01-01

    The 3rd Generation Partnership Project has recently started the standardization process for LTE-Advanced, as a major evolution step of UTRAN LTE Release 8. One of the key enhancing technologies being studied that may help to fulfill the challenging performance targets of LTE-Advanced networks is ...

  14. Quality and safety education for advanced nursing practice.

    Science.gov (United States)

    Cronenwett, Linda; Sherwood, Gwen; Pohl, Joanne; Barnsteiner, Jane; Moore, Shirley; Sullivan, Dori Taylor; Ward, Deborah; Warren, Judith

    2009-01-01

    The Quality and Safety Education for Nurses (QSEN) project is a national initiative to transform nursing education to integrate quality and safety competencies. This article describes a two-year process to generate educational objectives related to quality and safety competency development in graduate programs that prepare advanced practice nurses in clinical roles. Knowledge, skills, and attitudes for each of 6 competencies are proposed to stimulate development of teaching strategies in programs preparing the next generation of advanced practice nurses.

  15. Next Generation Energy. A study; Next Generation Energy. Studie

    Energy Technology Data Exchange (ETDEWEB)

    Reichert, Frank; Kitvarametha, Saman; Lehmann, Jochen; Ruhoff, Tim

    2010-07-01

    Under the short title 'Next Generation Energy', this publication discusses the complex problem of energy supply for the future. The authors attempt to identify the key issues that must be tackled, the business opportunities arising out of these issues, their practical feasibility and social impact. One of the findings of the study is the fact that consumers today are ready to buy electric-powered cars but there are not enough commercially available electric vehicles. The study is an attempt to tackle and advance this important and logistically complex issue. (orig.)

  16. Keystream Generator Based On Simulated Annealing

    Directory of Open Access Journals (Sweden)

    Ayad A. Abdulsalam

    2011-01-01

    Full Text Available Advances in the design of keystream generator using heuristic techniques are reported. A simulated annealing algorithm for generating random keystream with large complexity is presented. Simulated annealing technique is adapted to locate these requirements. The definitions for some cryptographic properties are generalized, providing a measure suitable for use as an objective function in a simulated annealing algorithm, seeking randomness that satisfy both correlation immunity and the large linear complexity. Results are presented demonstrating the effectiveness of the method.

  17. Geospatial Standards and the Knowledge Generation Lifescycle

    Science.gov (United States)

    Khalsa, Siri Jodha S.; Ramachandran, Rahul

    2014-01-01

    Standards play an essential role at each stage in the sequence of processes by which knowledge is generated from geoscience observations, simulations and analysis. This paper provides an introduction to the field of informatics and the knowledge generation lifecycle in the context of the geosciences. In addition we discuss how the newly formed Earth Science Informatics Technical Committee is helping to advance the application of standards and best practices to make data and data systems more usable and interoperable.

  18. Introducing advanced nuclear fuel cycles in Canada

    International Nuclear Information System (INIS)

    Duret, M.F.

    1978-05-01

    The ability of several different advanced fuel cycles to provide energy for a range of energy growth scenarios has been examined for a few special situations of interest in Canada. Plutonium generated from the CANDU-PHW operating on natural uranium is used to initiate advanced fuel cycles in the year 2000. The four fuel cycles compared are: 1) natural uranium in the CANDU-PHW; 2) high burnup thorium cycle in the CANDU-PHW; 3) self-sufficient thorium cycle in the CANDU-PHW; 4) plutonium-uranium cycle in a fast breeder reactor. The general features of the results are quite clear. While any plutonium generated prior to the introduction of the advanced fuel cycle remains, system requirements for natural uranium for each of the advanced fuel cycles are the same and are governed by the rate at which plants operating on natural uranium can be retired. When the accumulated plutonium inventory has been entirely used, natural uranium is again required to provide inventory for the advanced fuel cycle reactors. The time interval during which no uranium is required varies only from about 25 to 40 years for both thorium cycles, depending primarily on the energy growth rate. The breeder does not require the entire plutonium inventory produced and so would call for less processing of fuel from the PHW reactors. (author)

  19. Extended evaluation of a phase 1/2 trial on dosing, safety, immunogenicity, and overall survival after immunizations with an advanced-generation Ad5 [E1-, E2b-]-CEA(6D) vaccine in late-stage colorectal cancer.

    Science.gov (United States)

    Balint, Joseph P; Gabitzsch, Elizabeth S; Rice, Adrian; Latchman, Yvette; Xu, Younong; Messerschmidt, Gerald L; Chaudhry, Arvind; Morse, Michael A; Jones, Frank R

    2015-08-01

    A phase 1/2 clinical trial evaluating dosing, safety, immunogenicity, and overall survival on metastatic colorectal cancer (mCRC) patients after immunotherapy with an advanced-generation Ad5 [E1-, E2b-]-CEA(6D) vaccine was performed. We report our extended observations on long-term overall survival and further immune analyses on a subset of treated patients including assessment of cytolytic T cell responses, T regulatory (Treg) to T effector (Teff) cell ratios, flow cytometry on peripheral blood mononuclear cells (PBMCs), and determination of HLA-A2 status. An overall survival of 20 % (median survival 11 months) was observed during long-term follow-up, and no long-term adverse effects were reported. Cytolytic T cell responses increased after immunizations, and cell-mediated immune (CMI) responses were induced whether or not patients were HLA-A2 positive or Ad5 immune. PBMC samples from a small subset of patients were available for follow-up immune analyses. It was observed that the levels of carcinoembryonic antigen (CEA)-specific CMI activity decreased from their peak values during follow-up in five patients analyzed. Preliminary results revealed that activated CD4+ and CD8+ T cells were detected in a post-immunization sample exhibiting high CMI activity. Treg to Teff cell ratios were assessed, and samples from three of five patients exhibited a decrease in Treg to Teff cell ratio during the treatment protocol. Based upon the favorable safety and immunogenicity data obtained, we plan to perform an extensive immunologic and survival analysis on mCRC patients to be enrolled in a randomized/controlled clinical trial that investigates Ad5 [E1-, E2b-]-CEA(6D) as a single agent with booster immunizations.

  20. NEXT GENERATION TURBINE SYSTEM STUDY

    Energy Technology Data Exchange (ETDEWEB)

    Frank Macri

    2002-02-28

    Rolls-Royce has completed a preliminary design and marketing study under a Department of Energy (DOE) cost shared contract (DE-AC26-00NT40852) to analyze the feasibility of developing a clean, high efficiency, and flexible Next Generation Turbine (NGT) system to meet the power generation market needs of the year 2007 and beyond. Rolls-Royce evaluated the full range of its most advanced commercial aerospace and aeroderivative engines alongside the special technologies necessary to achieve the aggressive efficiency, performance, emissions, economic, and flexibility targets desired by the DOE. Heavy emphasis was placed on evaluating the technical risks and the economic viability of various concept and technology options available. This was necessary to ensure the resulting advanced NGT system would provide extensive public benefits and significant customer benefits without introducing unacceptable levels of technical and operational risk that would impair the market acceptance of the resulting product. Two advanced cycle configurations were identified as offering significant advantages over current combined cycle products available in the market. In addition, balance of plant (BOP) technologies, as well as capabilities to improve the reliability, availability, and maintainability (RAM) of industrial gas turbine engines, have been identified. A customer focused survey and economic analysis of a proposed Rolls-Royce NGT product configuration was also accomplished as a part of this research study. The proposed Rolls-Royce NGT solution could offer customers clean, flexible power generation systems with very high efficiencies, similar to combined cycle plants, but at a much lower specific cost, similar to those of simple cycle plants.

  1. Advances in lung ultrasound.

    Science.gov (United States)

    Francisco, Miguel José; Rahal, Antonio; Vieira, Fabio Augusto Cardillo; Silva, Paulo Savoia Dias da; Funari, Marcelo Buarque de Gusmão

    2016-01-01

    Ultrasound examination of the chest has advanced in recent decades. This imaging modality is currently used to diagnose several pathological conditions and provides qualitative and quantitative information. Acoustic barriers represented by the aerated lungs and the bony framework of the chest generate well-described sonographic artifacts that can be used as diagnostic aids. The normal pleural line and A, B, C, E and Z lines (also known as false B lines) are artifacts with specific characteristics. Lung consolidation and pneumothorax sonographic patterns are also well established. Some scanning protocols have been used in patient management. The Blue, FALLS and C.A.U.S.E. protocols are examples of algorithms using artifact combinations to achieve accurate diagnoses. Combined chest ultrasonography and radiography are often sufficient to diagnose and manage lung and chest wall conditions. Chest ultrasonography is a highly valuable diagnostic tool for radiologists, emergency and intensive care physicians. RESUMO O exame ultrassonográfico do tórax avançou nas últimas décadas, sendo utilizado para o diagnóstico de inúmeras condições patológicas, e fornecendo informações qualitativas e quantitativas. Os pulmões aerados e o arcabouço ósseo do tórax representam barreira sonora para o estudo ultrassonográfico, gerando artefatos que, bem conhecidos, são utilizados como ferramentas diagnósticas. Eco pleural normal, linhas A, linhas B, linhas C, linhas E e Z (conhecidas como falsas linhas B) são artefatos com características peculiares. Os padrões de consolidação e de pneumotórax também são bem estabelecidos. Alguns protocolos têm sido utilizados no manuseio dos pacientes: Blue Protocol, Protocolo FALLS e Protocolo C.A.U.S.E são exemplos de três propostas que, por meio da associação entre os artefatos, permitem sugerir diagnósticos precisos. A ultrassonografia de tórax, aliada à radiografia de tórax, muitas vezes é suficiente para o diagn

  2. Electrical power generating system. [for windpowered generation

    Science.gov (United States)

    Nola, F. J. (Inventor)

    1981-01-01

    An alternating current power generation system adopted to inject power in an already powered power line is discussed. The power generating system solves to adjustably coup an induction motor, as a generator, to an ac power line wherein the motor and power line are connected through a triac. The triac is regulated to normally turn on at a relatively late point in each half cycle of its operation, whereby at less than operating speed, and thus when the induction motor functions as a motor rather than as a generator, power consumption from the line is substantially reduced. The principal application will be for windmill powered generation.

  3. Advanced information society(7)

    Science.gov (United States)

    Chiba, Toshihiro

    Various threats are hiding in advanced informationalized society. As we see car accident problems in motorization society light aspects necessarily accompy shady ones. Under the changing circumstances of advanced informationalization added values of information has become much higher. It causes computer crime, hacker, computer virus to come to the surface. In addition it can be said that infringement of intellectual property and privacy are threats brought by advanced information. Against these threats legal, institutional and insurance measures have been progressed, and newly security industry has been established. However, they are not adequate individually or totally. The future vision should be clarified, and countermeasures according to the visions have to be considered.

  4. Random number generators and causality

    International Nuclear Information System (INIS)

    Larrondo, H.A.; Martin, M.T.; Gonzalez, C.M.; Plastino, A.; Rosso, O.A.

    2006-01-01

    We advance a prescription to randomize physical or algorithmic Random Number Generators (RNG's) that do not pass Marsaglia's DIEHARD test suite and discuss a special physical quantifier, based on an intensive statistical complexity measure, that is able to adequately assess the improvements produced thereby. Eight RNG's are evaluated and the associated results are compared to those obtained by recourse to Marsaglia's DIEHARD test suite. Our quantifier, which is evaluated using causality arguments, can forecast whether a given RNG will pass the above mentioned test

  5. Distributed generation induction and permanent magnet generators

    CERN Document Server

    Lai, L

    2007-01-01

    Distributed power generation is a technology that could help to enable efficient, renewable energy production both in the developed and developing world. It includes all use of small electric power generators, whether located on the utility system, at the site of a utility customer, or at an isolated site not connected to the power grid. Induction generators (IGs) are the cheapest and most commonly used technology, compatible with renewable energy resources. Permanent magnet (PM) generators have traditionally been avoided due to high fabrication costs; however, compared with IGs they are more reliable and productive. Distributed Generation thoroughly examines the principles, possibilities and limitations of creating energy with both IGs and PM generators. It takes an electrical engineering approach in the analysis and testing of these generators, and includes diagrams and extensive case study examples o better demonstrate how the integration of energy sources can be accomplished. The book also provides the ...

  6. Lithium batteries advanced technologies and applications

    CERN Document Server

    Scrosati, Bruno; Schalkwijk, Walter A van; Hassoun, Jusef

    2013-01-01

    Explains the current state of the science and points the way to technological advances First developed in the late 1980s, lithium-ion batteries now power everything from tablet computers to power tools to electric cars. Despite tremendous progress in the last two decades in the engineering and manufacturing of lithium-ion batteries, they are currently unable to meet the energy and power demands of many new and emerging devices. This book sets the stage for the development of a new generation of higher-energy density, rechargeable lithium-ion batteries by advancing battery chemistry and ident

  7. Advances in software science and technology

    CERN Document Server

    Ohno, Yoshio; Kamimura, Tsutomu

    1991-01-01

    Advances in Software Science and Technology, Volume 2 provides information pertinent to the advancement of the science and technology of computer software. This book discusses the various applications for computer systems.Organized into four parts encompassing 12 chapters, this volume begins with an overview of categorical frameworks that are widely used to represent data types in computer science. This text then provides an algorithm for generating vertices of a smoothed polygonal line from the vertices of a digital curve or polygonal curve whose position contains a certain amount of error. O

  8. Emergent web intelligence advanced information retrieval

    CERN Document Server

    Badr, Youakim; Abraham, Ajith; Hassanien, Aboul-Ella

    2010-01-01

    Web Intelligence explores the impact of artificial intelligence and advanced information technologies representing the next generation of Web-based systems, services, and environments, and designing hybrid web systems that serve wired and wireless users more efficiently. Multimedia and XML-based data are produced regularly and in increasing way in our daily digital activities, and their retrieval must be explored and studied in this emergent web-based era. 'Emergent Web Intelligence: Advanced information retrieval, provides reviews of the related cutting-edge technologies and insights. It is v

  9. Advanced Stirling Convertor Testing at GRC

    Science.gov (United States)

    Schifer, Nick; Oriti, Salvatore M.

    2013-01-01

    NASA Glenn Research Center (GRC) has been supporting development of the Advanced Stirling Radioisotope Generator (ASRG) since 2006. A key element of the ASRG project is providing life, reliability, and performance testing of the Advanced Stirling Convertor (ASC). The latest version of the ASC, deemed ASC-E3, is of a design identical to the forthcoming flight convertors. The first pair of ASC-E3 units was delivered in December 2012. GRC has begun the process of adding these units to the catalog of ongoing Stirling convertor operation. This process includes performance verification, which examines the data from various tests to validate the convertors performance to the product specification.

  10. Advanced smartgrids for distribution system operators

    CERN Document Server

    Boillot, Marc

    2014-01-01

    The dynamic of the Energy Transition is engaged in many region of the World. This is a real challenge for electric systems and a paradigm shift for existing distribution networks. With the help of "advanced" smart technologies, the Distribution System Operators will have a central role to integrate massively renewable generation, electric vehicle and demand response programs. Many projects are on-going to develop and assess advanced smart grids solutions, with already some lessons learnt. In the end, the Smart Grid is a mean for Distribution System Operators to ensure the quality and the secu

  11. Advanced Demonstration and Test Reactor Options Study

    Energy Technology Data Exchange (ETDEWEB)

    Petti, David Andrew [Idaho National Lab. (INL), Idaho Falls, ID (United States); Hill, R. [Argonne National Lab. (ANL), Argonne, IL (United States); Gehin, J. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Gougar, Hans David [Idaho National Lab. (INL), Idaho Falls, ID (United States); Strydom, Gerhard [Idaho National Lab. (INL), Idaho Falls, ID (United States); Heidet, F. [Argonne National Lab. (ANL), Argonne, IL (United States); Kinsey, J. [Idaho National Lab. (INL), Idaho Falls, ID (United States); Grandy, Christopher [Argonne National Lab. (ANL), Argonne, IL (United States); Qualls, A. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Brown, Nicholas [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Powers, J. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Hoffman, E. [Argonne National Lab. (ANL), Argonne, IL (United States); Croson, D. [Idaho National Lab. (INL), Idaho Falls, ID (United States)

    2017-01-01

    Global efforts to address climate change will require large-scale decarbonization of energy production in the United States and elsewhere. Nuclear power already provides 20% of electricity production in the United States (U.S.) and is increasing in countries undergoing rapid growth around the world. Because reliable, grid-stabilizing, low emission electricity generation, energy security, and energy resource diversity will be increasingly valued, nuclear power’s share of electricity production has a potential to grow. In addition, there are non electricity applications (e.g., process heat, desalination, hydrogen production) that could be better served by advanced nuclear systems. Thus, the timely development, demonstration, and commercialization of advanced nuclear reactors could diversify the nuclear technologies available and offer attractive technology options to expand the impact of nuclear energy for electricity generation and non-electricity missions. The purpose of this planning study is to provide transparent and defensible technology options for a test and/or demonstration reactor(s) to be built to support public policy, innovation and long term commercialization within the context of the Department of Energy’s (DOE’s) broader commitment to pursuing an “all of the above” clean energy strategy and associated time lines. This planning study includes identification of the key features and timing needed for advanced test or demonstration reactors to support research, development, and technology demonstration leading to the commercialization of power plants built upon these advanced reactor platforms. This planning study is consistent with the Congressional language contained within the fiscal year 2015 appropriation that directed the DOE to conduct a planning study to evaluate “advanced reactor technology options, capabilities, and requirements within the context of national needs and public policy to support innovation in nuclear energy

  12. Random pulse generator

    International Nuclear Information System (INIS)

    Guo Ya'nan; Jin Dapeng; Zhao Dixin; Liu Zhen'an; Qiao Qiao; Chinese Academy of Sciences, Beijing

    2007-01-01

    Due to the randomness of radioactive decay and nuclear reaction, the signals from detectors are random in time. But normal pulse generator generates periodical pulses. To measure the performances of nuclear electronic devices under random inputs, a random generator is necessary. Types of random pulse generator are reviewed, 2 digital random pulse generators are introduced. (authors)

  13. Advanced Transportation Institute 2009.

    Science.gov (United States)

    2009-09-01

    The eighth version of the Advanced Transportation Institute (ATI-09) was conducted in 2009 to encourage high school students to pursue careers in the field of transportation engineering. The University Transportation Center for Alabama partnered with...

  14. Descendants and advance directives.

    Science.gov (United States)

    Buford, Christopher

    2014-01-01

    Some of the concerns that have been raised in connection to the use of advance directives are of the epistemic variety. Such concerns highlight the possibility that adhering to an advance directive may conflict with what the author of the directive actually wants (or would want) at the time of treatment. However, at least one objection to the employment of advance directives is metaphysical in nature. The objection to be discussed here, first formulated by Rebecca Dresser and labeled by Allen Buchanan as the slavery argument and David DeGrazia the someone else problem, aims to undermine the legitimacy of certain uses of advance directives by concluding that such uses rest upon an incorrect assumption about the identity over time of those ostensibly governed by the directives. There have been numerous attempts to respond to this objection. This paper aims to assess two strategies that have been pursued to cope with the problem.

  15. Advanced Welding Concepts

    Science.gov (United States)

    Ding, Robert J.

    2010-01-01

    Four advanced welding techniques and their use in NASA are briefly reviewed in this poster presentation. The welding techniques reviewed are: Solid State Welding, Friction Stir Welding (FSW), Thermal Stir Welding (TSW) and Ultrasonic Stir Welding.

  16. Advanced walling systems

    CSIR Research Space (South Africa)

    De Villiers, A

    2010-01-01

    Full Text Available The question addressed by this chapter is: How should advanced walling systems be planned, designed, built, refurbished, and end their useful lives, to classify as smart, sustainable, green or eco-building environments?...

  17. [Advanced resuscitation of adults

    DEFF Research Database (Denmark)

    Lippert, F.K.; Lauritsen, T.L.; Torp-Pedersen, C.

    2008-01-01

    International and European Resuscitation Council (ERC) Guidelines for Resuscitation 2005 implicate major changes in resuscitation, including new universal treatment algorithms. This brief summary of Guidelines 2005 for advanced resuscitation of adult cardiac arrest victims is based upon the ERC...

  18. Advanced control room evaluation

    International Nuclear Information System (INIS)

    O'Hara, J.M.; Wachtel, J.

    1991-01-01

    Advanced control rooms (ACRs) for future nuclear power plants (NPPs) are being designed utilizing computer-based technologies. The U.S. Nuclear Regulatory Commission reviews the human engineering aspects of such control rooms to ensure that they are designed to good human factors engineering principles and that operator performance and reliability are appropriately supported in order to protect public health and safety. This paper describes the rationale and general approach to the development of a human factors review environment, the types of advanced technologies being addressed, the human factors issues associated with advanced technology, and the current state-of-the-art of human factors guidelines for advanced human-system interfaces (HSIs). The proposed approach to ACR review would track the design and implementation process through the application of review guidelines reflecting four review modules: planning, design process analysis, human factors engineering review, and dynamic performance evaluation

  19. Advanced Missile Signature Center

    Data.gov (United States)

    Federal Laboratory Consortium — The Advanced Missile Signature Center (AMSC) is a national facility supporting the Missile Defense Agency (MDA) and other DoD programs and customers with analysis,...

  20. Advanced care directives

    Science.gov (United States)

    ... to have and what treatment you want no matter how ill you are. Writing an advance care ... ADAM Health Solutions. About MedlinePlus Site Map FAQs Customer Support Get email updates Subscribe to RSS Follow ...

  1. Advance Payment ACO Model

    Data.gov (United States)

    U.S. Department of Health & Human Services — The Advance Payment Model is designed for physician-based and rural providers who have come together voluntarily to give coordinated high quality care to the...

  2. Advanced Chemistry Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — Description/History: Chemistry laboratoryThe Advanced Chemistry Laboratory (ACL) is a unique facility designed for working with the most super toxic compounds known...

  3. Dyspnea during Advanced Cancer

    Science.gov (United States)

    ... when the information is about children. Dyspnea During Advanced Cancer Key Points Many conditions can cause dyspnea. ... Echocardiography : A procedure in which high-energy sound waves ( ultrasound ) are bounced off internal tissues or organs ...

  4. Ferumoxtran-10 advanced magnetics.

    NARCIS (Netherlands)

    Leenders, W.P.J.

    2003-01-01

    Ferumoxtran-10 (Combidex) is an ultra-small superparamagnetic iron oxide molecular resonance imaging contrast agent under development by Advanced Magnetics Ltd and Guerbet for the principal indication of lymph node imaging.

  5. Advanced Microanalysis Facility

    Data.gov (United States)

    Federal Laboratory Consortium — The Advanced Microanalysis Facility fully integrates capabilities for chemical and structural analysis of electronic materials and devices for the U.S. Army and DoD....

  6. Advanced Welding Applications

    Science.gov (United States)

    Ding, Robert J.

    2010-01-01

    Some of the applications of advanced welding techniques are shown in this poster presentation. Included are brief explanations of the use on the Ares I and Ares V launch vehicle and on the Space Shuttle Launch vehicle. Also included are microstructural views from four advanced welding techniques: Variable Polarity Plasma Arc (VPPA) weld (fusion), self-reacting friction stir welding (SR-FSW), conventional FSW, and Tube Socket Weld (TSW) on aluminum.

  7. Joining of advanced materials

    CERN Document Server

    Messler, Robert W

    1993-01-01

    Provides an unusually complete and readable compilation of the primary and secondary options for joining conventional materials in non-conventional ways. Provides unique coverage of adhesive bonding using both organic and inorganic adhesives, cements and mortars. Focuses on materials issues without ignoring issues related to joint design, production processing, quality assurance, process economics, and joining performance in service.Joining of advanced materials is a unique treatment of joining of both conventional and advanced metals andalloys, intermetallics, ceramics, glasses, polymers, a

  8. Advances in bistatic radar

    CERN Document Server

    Willis, Nick

    2007-01-01

    Advances in Bistatic Radar updates and extends bistatic and multistatic radar developments since publication of Willis' Bistatic Radar in 1991. New and recently declassified military applications are documented. Civil applications are detailed including commercial and scientific systems. Leading radar engineers provide expertise to each of these applications. Advances in Bistatic Radar consists of two major sections: Bistatic/Multistatic Radar Systems and Bistatic Clutter and Signal Processing. Starting with a history update, the first section documents the early and now declassified military

  9. Advanced Propulsor Design Studies

    Science.gov (United States)

    1985-06-01

    Report No. CG-D-1-86 ADVANCED PROPULSOR DESIGN STUDIES BY WALTER S. GEARHART 00 DTIC ;00 ELECTE MAR 4 S86 B II This document is available to the U;S...Organization Code Advanced Propulsor Design Studies _.__________ 0. Performing Orgoni ation Report No.7. A’jthoart g) Walter S. Gearhart 9. Performing...USCG Hulls Considered in the Preliminary Design Studies . . . . . . * 2 Preliminary Design Investigation . . . . . . . . .. . . . . . . . .. 3

  10. Advanced Stellar Compass

    DEFF Research Database (Denmark)

    Madsen, Peter Buch; Jørgensen, John Leif; Thuesen, Gøsta

    1997-01-01

    This document describes all interface properties for the Advanced Stellar Compass, developed for the German Research Satellite "CHAMP". Basic operations, modes, software protocol, calibration methods and closed loop test strategies are described.......This document describes all interface properties for the Advanced Stellar Compass, developed for the German Research Satellite "CHAMP". Basic operations, modes, software protocol, calibration methods and closed loop test strategies are described....

  11. Advances in atomic spectroscopy

    CERN Document Server

    Sneddon, J

    1997-01-01

    This series describes selected advances in the area of atomic spectroscopy. It is primarily intended for the reader who has a background in atmoic spectroscopy; suitable to the novice and expert. Although a widely used and accepted method for metal and non-metal analysis in a variety of complex samples, Advances in Atomic Spectroscopy covers a wide range of materials. Each Chapter will completely cover an area of atomic spectroscopy where rapid development has occurred.

  12. IPv6: The Next Generation Internet Protocol

    Indian Academy of Sciences (India)

    GENERAL I ARTICLE. IPv6: The Next Generation Internet Protocol. 1. IPv4 and its Shortcomings. Harsha Srinath is currently pursuing his MS degree in Computer. Science at the Center for. Advanced Computer. Studies (CACS) in. University of Louisiana at. Lafayette, USA. His research interests include networking with an.

  13. Educating College Students of the Net Generation

    Science.gov (United States)

    Worley, Karen

    2011-01-01

    Faculty and administrators of higher education today face a challenge with their student populations, many of whom are part of what is known as the net generation. As students become more technologically advanced, faculty must be technologically ready to meet the needs of students. Many college faculty and administrators are from earlier…

  14. Amharic Character Generator | Gessesse | Zede Journal

    African Journals Online (AJOL)

    Zede Journal. Journal Home · ABOUT THIS JOURNAL · Advanced Search · Current Issue · Archives · Journal Home > Vol 7 (1986) >. Log in or Register to get access to full text downloads. Username, Password, Remember me, or Register. Amharic Character Generator. GA Gessesse. Abstract. No Abstract. Full Text:.

  15. Entropy Generation in a Chemical Reaction

    Science.gov (United States)

    Miranda, E. N.

    2010-01-01

    Entropy generation in a chemical reaction is analysed without using the general formalism of non-equilibrium thermodynamics at a level adequate for advanced undergraduates. In a first approach to the problem, the phenomenological kinetic equation of an elementary first-order reaction is used to show that entropy production is always positive. A…

  16. Advanced TCA Backplane Tester

    CERN Document Server

    Oltean, Alexandra Dana

    2004-01-01

    At the beginning of 2003, the PICMG group adopted the AdvancedTCA (Advanced Telecom Computing Architecture) standard. The 10Gb/s backplane of the AdvancedTCA chassis is well specified in the standard but it remains however a high end product, which can be itself subject to printed circuit board manufacturing control problems that could greatly affect its quality control. In order to study the practical aspects of high speed Ethernet switching at 10Gb/s and to validate the signal integrity of the AdvancedTCA backplane, we developed a Backplane Tester. The tester system is able of running monitored PRBS traffic at 3.125Gb/s over every link on the AdvancedTCA backplane simultaneously and to monitor any possible connectivity failure immediately in terms of link and slot position inside the chassis. The present report presents the architectural hardware design, the control structure and software aspects of the AdvancedTCA Backplane Tester design.

  17. United States advanced technologies

    International Nuclear Information System (INIS)

    Longenecker, J.R.

    1985-01-01

    In the United States, the advanced technologies have been applied to uranium enrichment as a means by which it can be assured that nuclear fuel cost will remain competitive in the future. The United States is strongly committed to the development of advanced enrichment technology, and has brought both advanced gas centrifuge (AGC) and atomic vapor laser isotope separation (AVLIS) programs to a point of significant technical refinement. The ability to deploy advanced technologies is the basis for the confidence in competitive future price. Unfortunately, the development of advanced technologies is capital intensive. The year 1985 is the key year for advanced technology development in the United States, since the decision on the primary enrichment technology for the future, AGC or AVLIS, will be made shortly. The background on the technology selection process, the highlights of AGC and AVLIS programs and the way to proceed after the process selection are described. The key objective is to maximize the sales volume and minimize the operating cost. This will help the utilities in other countries supply low cost energy on a reliable, long term basis. (Kako, I.)

  18. Hazardous Waste Generators

    Data.gov (United States)

    Vermont Center for Geographic Information — The HazWaste database contains generator (companies and/or individuals) site and mailing address information, waste generation, the amount of waste generated etc. of...

  19. MHD Power Generation

    Science.gov (United States)

    Kantrowitz, Arthur; Rosa, Richard J.

    1975-01-01

    Explains the operation of the Magnetohydrodynamic (MHD) generator and advantages of the system over coal, oil or nuclear powered generators. Details the development of MHD generators in the United States and Soviet Union. (CP)

  20. Recent advances in epilepsy genetics.

    Science.gov (United States)

    Orsini, Alessandro; Zara, Federico; Striano, Pasquale

    2018-02-22

    In last few years there has been rapid increase in the knowledge of epilepsy genetics. Nowadays, it is estimated that genetic epilepsies include over than 30% of all epilepsy syndromes. Several genetic tests are now available for diagnostic purposes in clinical practice. In particular, next-generation sequencing has proven to be effective in revealing gene mutations causing epilepsies in up to a third of the patients. This has lead also to functional studies that have given insight into disease pathophysiology and consequently to the identification of potential therapeutic targets opening the way of precision medicine for epilepsy patients. This minireview is focused on the most recent advances in genetics of epilepsies. We will also overview the modern genomic technologies and illustrate the diagnostic pathways in patients with genetic epilepsies. Finally, the potential implications for a personalized treatment (precision medicine) are also discussed. Copyright © 2017 Elsevier B.V. All rights reserved.

  1. Advance and permanent public information

    International Nuclear Information System (INIS)

    d'Oleon, C.

    1990-01-01

    The accident at CHERNOBYL highlighted one of the major problems facing the nuclear industry at present and during the years to come: the need to provide information. There are two aspects to this requirement: information at a time of crisis issued when an accident such as that at CHERNOBYL takes place, but which has to be based on a procedure set up before the crisis, and advance and permanent information which prepares the ground for information at a time of crisis. The requirement for information is of particular importance in France, given the preponderance of nuclear energy in the electricity generating industry. The procedure covers the principles which were forcefully asserted by the French public authorities during the CHERNOBYL crisis, the resources strengthened or established at that time, and finally, the introduction of a policy of wider-ranging communication which is based on the idea that one can never compromise with safety

  2. Advanced PWR fuel design concepts

    International Nuclear Information System (INIS)

    Andersor, C.K.; Harris, R.P.; Crump, M.W.; Fuhrman, N.

    1987-01-01

    For nearly 15 years, Combustion Engineering has provided pressurized water reactor fuel with the features most suppliers are now introducing in their advanced fuel designs. Zircaloy grids, removable upper end fittings, large fission gas plenum, high burnup, integral burnable poisons and sophisticated analytical methods are all features of C-E standard fuel which have been well proven by reactor performance. C-E's next generation fuel for pressurized water reactors features 24-month operating cycles, optimal lattice burnable poisons, increased resistance to common industry fuel rod failure mechanisms, and hardware and methodology for operating margin improvements. Application of these various improvements offer continued improvement in fuel cycle economics, plant operation and maintenance. (author)

  3. Recent advances in computational aerodynamics

    Science.gov (United States)

    Agarwal, Ramesh K.; Desse, Jerry E.

    1991-04-01

    The current state of the art in computational aerodynamics is described. Recent advances in the discretization of surface geometry, grid generation, and flow simulation algorithms have led to flowfield predictions for increasingly complex and realistic configurations. As a result, computational aerodynamics is emerging as a crucial enabling technology for the development and design of flight vehicles. Examples illustrating the current capability for the prediction of aircraft, launch vehicle and helicopter flowfields are presented. Unfortunately, accurate modeling of turbulence remains a major difficulty in the analysis of viscosity-dominated flows. In the future inverse design methods, multidisciplinary design optimization methods, artificial intelligence technology and massively parallel computer technology will be incorporated into computational aerodynamics, opening up greater opportunities for improved product design at substantially reduced costs.

  4. Power Generation for River and Tidal Generators

    Energy Technology Data Exchange (ETDEWEB)

    Muljadi, Eduard [National Renewable Energy Lab. (NREL), Golden, CO (United States); Wright, Alan [National Renewable Energy Lab. (NREL), Golden, CO (United States); Gevorgian, Vahan [National Renewable Energy Lab. (NREL), Golden, CO (United States); Donegan, James [Ocean Renewable Power Company (ORPC), Portland, ME (United States); Marnagh, Cian [Ocean Renewable Power Company (ORPC), Portland, ME (United States); McEntee, Jarlath [Ocean Renewable Power Company (ORPC), Portland, ME (United States)

    2016-06-01

    Renewable energy sources are the second largest contributor to global electricity production, after fossil fuels. The integration of renewable energy continued to grow in 2014 against a backdrop of increasing global energy consumption and a dramatic decline in oil prices during the second half of the year. As renewable generation has become less expensive during recent decades, and it becomes more accepted by the global population, the focus on renewable generation has expanded from primarily wind and solar to include new types with promising future applications, such as hydropower generation, including river and tidal generation. Today, hydropower is considered one of the most important renewable energy sources. In river and tidal generation, the input resource flow is slower but also steadier than it is in wind or solar generation, yet the level of water turbulent flow may vary from one place to another. This report focuses on hydrokinetic power conversion.

  5. Archetyping: A software generation and management methodology

    Science.gov (United States)

    Rothman, Hugh B.; Przybylinski, Stanley M.

    1988-01-01

    Many knowledge based software generation methods have been proposed to improve software quality and programmer productivity. Several government and industry initiatives have focused on software reusability as one solution to these problems. DARTS (trademark), a General Dynamics proprietary symbolic processing technology, provides a unique solution to the reuse problem: archtyping. Archtyping is the embedding of high order language statements in text files. An advanced macroprocessor uses the text files to generate new versions of complex software systems. A DARTS program, the Software Generation and Configuration Management (SGCM) System automates the archtyping process and maintenance cycle. The DARTS technology is briefly discussed, archtyping is described, and the SGCM system is presented in detail.

  6. AGATA - Advanced GAmma Tracking Array

    Energy Technology Data Exchange (ETDEWEB)

    Akkoyun, S. [Department of Physics, Faculty of Science, Ankara University, 06100 Tandogan, Ankara (Turkey); Algora, A. [IFIC, CSIC-Universitat de Valencia, E-46980 Paterna (Spain); Alikhani, B. [IKP, TU Darmstadt, Schlossgartenstrasse 9, D-64289 Darmstadt (Germany); Ameil, F. [GSI Helmholtzzentrum fuer Schwerionenforschung GmbH, D-64291 Darmstadt (Germany); Angelis, G. de [INFN Laboratori Nazionali di Legnaro, IT-35020 Padova (Italy); Arnold, L. [Universite de Strasbourg, IPHC, 23 rue du Loess, 67037 Strasbourg (France); CNRS, UMR 7178, 67037 Strasbourg (France); Astier, A. [CSNSM, CNRS, IN2P3, Universite Paris-Sud, F-91405 Orsay (France); Atac, A. [Department of Physics, Faculty of Science, Ankara University, 06100 Tandogan, Ankara (Turkey); Department of Physics and Astronomy, Uppsala University, Uppsala (Sweden); Royal Institute of Technology, SE-10691 Stockholm (Sweden); Aubert, Y. [IPNO, CNRS/IN2P3, Universite Paris-Sud, F-91406 Orsay (France); Aufranc, C. [Universite de Lyon, Universite Lyon 1, CNRS-IN2P3, Institut de Physique Nucleaire de Lyon, F-69622 Villeurbanne (France); Austin, A. [STFC Daresbury Laboratory, Daresbury, Warrington WA4 4AD (United Kingdom); Aydin, S. [INFN Sezione di Padova, IT-35131 Padova (Italy); Azaiez, F. [IPNO, CNRS/IN2P3, Universite Paris-Sud, F-91406 Orsay (France); Badoer, S. [INFN Laboratori Nazionali di Legnaro, IT-35020 Padova (Italy); Balabanski, D.L. [Institute for Nuclear Research and Nuclear Energy, Bulgarian Academy of Sciences, Sofia (Bulgaria); Barrientos, D. [IFIC, CSIC-Universitat de Valencia, E-46980 Paterna (Spain); and others

    2012-03-11

    The Advanced GAmma Tracking Array (AGATA) is a European project to develop and operate the next generation {gamma}-ray spectrometer. AGATA is based on the technique of {gamma}-ray energy tracking in electrically segmented high-purity germanium crystals. This technique requires the accurate determination of the energy, time and position of every interaction as a {gamma} ray deposits its energy within the detector volume. Reconstruction of the full interaction path results in a detector with very high efficiency and excellent spectral response. The realisation of {gamma}-ray tracking and AGATA is a result of many technical advances. These include the development of encapsulated highly segmented germanium detectors assembled in a triple cluster detector cryostat, an electronics system with fast digital sampling and a data acquisition system to process the data at a high rate. The full characterisation of the crystals was measured and compared with detector-response simulations. This enabled pulse-shape analysis algorithms, to extract energy, time and position, to be employed. In addition, tracking algorithms for event reconstruction were developed. The first phase of AGATA is now complete and operational in its first physics campaign. In the future AGATA will be moved between laboratories in Europe and operated in a series of campaigns to take advantage of the different beams and facilities available to maximise its science output. The paper reviews all the achievements made in the AGATA project including all the necessary infrastructure to operate and support the spectrometer.

  7. Advanced Collaborative Emissions Study (ACES)

    Energy Technology Data Exchange (ETDEWEB)

    Greenbaum, Daniel; Costantini, Maria; Van Erp, Annemoon; Shaikh, Rashid; Bailey, Brent; Tennant, Chris; Khalek, Imad; Mauderly, Joe; McDonald, Jacob; Zielinska, Barbara; Bemis, Jeffrey; Storey, John; Hallberg, Lance; Clark, Nigel

    2013-12-31

    The objective of the Advanced Collaborative Emissions Study (ACES) was to determine before widespread commercial deployment whether or not the new, energy-efficient, heavy duty diesel engines (2007 and 2010 EPA Emissions Standards Compliant) may generate anticipated toxic emissions that could adversely affect the environment and human health. ACES was planned to take place in three phases. In Phase 1, extensive emissions characterization of four production-intent prototype engine and control systems designed to meet 2007 standards for nitrogen oxides (NOx) and particulate matter (PM) was conducted at an existing emissions characterization facility: Southwest Research Institute (SwRI). One of the tested engines was selected (at random, after careful comparison of results) for health testing in Phase 3. In Phase 2, extensive emission characterization of three production-intent prototype engine and control systems meeting the 2010 standards (including more advanced NOx controls to meet the more stringent 2010 NOx standards) was conducted at the same test facility. In Phase 3, one engine/aftertreatment system selected from Phase 1 was further characterized during health effects studies (at an existing inhalation toxicology laboratory: Lovelace Respiratory Research Institute, [LRRI]) to form the basis of the ACES safety assessment. The Department of Energy (DOE) award provided funding for emissions characterization in Phases 1 and 2 as well as exposure characterization in Phase 3. The main health analyses in Phase 3 were funded separately and are not reported here.

  8. Delayed coker fractionator advanced control

    Energy Technology Data Exchange (ETDEWEB)

    Jaisinghani, R.; Minter, B. (ABB SIMCON Inc., Houston, TX (United States)); Tica, A.; Puglesi, A.; Ojeda, R. (Yacimentos Petroliferos Fiscales, Mendoza (Argentina))

    1993-08-01

    In a delayed coking process, as coke drum switches are made, rapid changes occur in both the fractionator feed rate and composition. With conventional control, it is not unusual to see long transient behavior of large swings in both quality and flowrates of coker gas oils. This can extract a heavy economic toll, not only in coker operation, but in the operation of downstream units as the upset is propagated. An advanced process control application (APC) was recently implemented on the coker fractionator at the Yacimentos Petroliferos Fiscales (YPF), Lujan de Cuyo Refinery, in Mendoza, Argentina. This coker fractionator control design was unique as it handled two different operating objectives: control of product qualities via tower temperature profile during normal operation and control of gas oil product flow ratio during drum switch. This combination of control objectives in one multivariable predictive control program was achieved by including special logic to decouple the individual tuning requirements. Also, additional logic was included to unambiguously detect and identify drum switch and drum steam out as discrete events within 30 seconds of their actual occurrence. These discrete events were then used as disturbance variables to minimize fractionator transient behavior. As a performance measure, the overhead temperature was controlled within 2 C to 2.5 C of its target, gas oil flows were stabilized during drum switches and steam generation via pump around was maximized. Overall, implementing advanced control for the delayed coker fractionator resulted in substantial benefits from product quality control, product flow control and minimized energy consumption.

  9. Physics of Compact Advanced Stellarators

    International Nuclear Information System (INIS)

    Zarnstorff, M.C.; Berry, L.A.; Brooks, A.; Fredrickson, E.; Fu, G.-Y.; Hirshman, S.; Hudson, S.; Ku, L.-P.; Lazarus, E.; Mikkelsen, D.; Monticello, D.; Neilson, G.H.; Pomphrey, N.; Reiman, A.; Spong, D.; Strickler, D.; Boozer, A.; Cooper, W.A.; Goldston, R.; Hatcher, R.; Isaev, M.; Kessel, C.; Lewandowski, J.; Lyon, J.; Merkel, P.; Mynick, H.; Nelson, B.E.; Nuehrenberg, C.; Redi, M.; Reiersen, W.; Rutherford, P.; Sanchez, R.; Schmidt, J.; White, R.B.

    2001-01-01

    Compact optimized stellarators offer novel solutions for confining high-beta plasmas and developing magnetic confinement fusion. The 3-D plasma shape can be designed to enhance the MHD stability without feedback or nearby conducting structures and provide drift-orbit confinement similar to tokamaks. These configurations offer the possibility of combining the steady-state low-recirculating power, external control, and disruption resilience of previous stellarators with the low-aspect ratio, high beta-limit, and good confinement of advanced tokamaks. Quasi-axisymmetric equilibria have been developed for the proposed National Compact Stellarator Experiment (NCSX) with average aspect ratio 4-4.4 and average elongation of approximately 1.8. Even with bootstrap-current consistent profiles, they are passively stable to the ballooning, kink, vertical, Mercier, and neoclassical-tearing modes for beta > 4%, without the need for external feedback or conducting walls. The bootstrap current generates only 1/4 of the magnetic rotational transform at beta = 4% (the rest is from the coils), thus the equilibrium is much less nonlinear and is more controllable than similar advanced tokamaks. The enhanced stability is a result of ''reversed'' global shear, the spatial distribution of local shear, and the large fraction of externally generated transform. Transport simulations show adequate fast-ion confinement and thermal neoclassical transport similar to equivalent tokamaks. Modular coils have been designed which reproduce the physics properties, provide good flux surfaces, and allow flexible variation of the plasma shape to control the predicted MHD stability and transport properties

  10. Next Generation Modeling Technology for High Speed Rotorcraft Project

    Data.gov (United States)

    National Aeronautics and Space Administration — Development of a new generation of high speed rotorcraft has been hampered by both an absence of strong predictive methods for rotors operating at very high advance...

  11. The ABWR in future power generation planning

    International Nuclear Information System (INIS)

    Redding, J.

    1998-01-01

    Advanced nuclear technology has reached the point of commercialization. Two advanced nuclear plants (ANPs) have been constructed in Japan and are reliably generating large amounts of low cost electricity. Taiwan is now in the process of licensing and constructing two more ANPs. Other countries have similar strategies to deploy advanced nuclear plants and the successful deployment of ANPs in Japan, Taiwan, China, and South Korea, coupled with international agreements to limit C02 emissions, will only reinforce these plans. Because they have a proven track record, ANPs will play an important role in meeting the conflicting needs of developing economies for more massive amounts of electricity and the need worldwide to limit C02 emissions. Use of advanced nuclear technology, in other words, provide these economies with a proven means to promote sustainable development. (author)

  12. Monte Carlo simulation models of breeding-population advancement.

    Science.gov (United States)

    J.N. King; G.R. Johnson

    1993-01-01

    Five generations of population improvement were modeled using Monte Carlo simulations. The model was designed to address questions that are important to the development of an advanced generation breeding population. Specifically we addressed the effects on both gain and effective population size of different mating schemes when creating a recombinant population for...

  13. NEXT GENERATION TURBINE PROGRAM

    Energy Technology Data Exchange (ETDEWEB)

    William H. Day

    2002-05-03

    The Next Generation Turbine (NGT) Program's technological development focused on a study of the feasibility of turbine systems greater than 30 MW that offer improvement over the 1999 state-of-the-art systems. This program targeted goals of 50 percent turndown ratios, 15 percent reduction in generation cost/kW hour, improved service life, reduced emissions, 400 starts/year with 10 minutes to full load, and multiple fuel usage. Improvement in reliability, availability, and maintainability (RAM), while reducing operations, maintenance, and capital costs by 15 percent, was pursued. This program builds on the extensive low emissions stationary gas turbine work being carried out by Pratt & Whitney (P&W) for P&W Power Systems (PWPS), which is a company under the auspices of the United Technologies Corporation (UTC). This study was part of the overall Department of Energy (DOE) NGT Program that extends out to the year 2008. A follow-on plan for further full-scale component hardware testing is conceptualized for years 2002 through 2008 to insure a smooth and efficient transition to the marketplace for advanced turbine design and cycle technology. This program teamed the National Energy Technology Laboratory (NETL), P&W, United Technologies Research Center (UTRC), kraftWork Systems Inc., a subcontractor on-site at UTRC, and Multiphase Power and Processing Technologies (MPPT), an off-site subcontractor. Under the auspices of the NGT Program, a series of analyses were performed to identify the NGT engine system's ability to serve multiple uses. The majority were in conjunction with a coal-fired plant, or used coal as the system fuel. Identified also was the ability of the NGT system to serve as the basis of an advanced performance cycle: the humid air turbine (HAT) cycle. The HAT cycle is also used with coal gasification in an integrated cycle HAT (IGHAT). The NGT systems identified were: (1) Feedwater heating retrofit to an existing coal-fired steam plant, which

  14. Advanced analysis methods in particle physics

    Energy Technology Data Exchange (ETDEWEB)

    Bhat, Pushpalatha C.; /Fermilab

    2010-10-01

    Each generation of high energy physics experiments is grander in scale than the previous - more powerful, more complex and more demanding in terms of data handling and analysis. The spectacular performance of the Tevatron and the beginning of operations of the Large Hadron Collider, have placed us at the threshold of a new era in particle physics. The discovery of the Higgs boson or another agent of electroweak symmetry breaking and evidence of new physics may be just around the corner. The greatest challenge in these pursuits is to extract the extremely rare signals, if any, from huge backgrounds arising from known physics processes. The use of advanced analysis techniques is crucial in achieving this goal. In this review, I discuss the concepts of optimal analysis, some important advanced analysis methods and a few examples. The judicious use of these advanced methods should enable new discoveries and produce results with better precision, robustness and clarity.

  15. Stabilized lasers for advanced gravitational wave detectors

    International Nuclear Information System (INIS)

    Willke, B; Danzmann, K; Kwee, P; Seifert, F; Frede, M; Kracht, D; Puncken, O; Schulz, B; Veltkamp, C; Wagner, S; Wessels, P; Winkelmann, L; King, P; Savage, R L Jr

    2008-01-01

    Second generation gravitational wave detectors require high power lasers with more than 100 W of output power and with very low temporal and spatial fluctuations. To achieve the demanding stability levels required, low noise techniques and adequate control actuators have to be part of the high power laser design. In addition feedback control and passive noise filtering is used to reduce the fluctuations in the so-called prestabilized laser system (PSL). In this paper, we discuss the design of a 200 W PSL which is under development for the Advanced LIGO gravitational wave detector and will present the first results. The PSL noise requirements for advanced gravitational wave detectors will be discussed in general and the stabilization scheme proposed for the Advanced LIGO PSL will be described

  16. Advanced hardware design for error correcting codes

    CERN Document Server

    Coussy, Philippe

    2015-01-01

    This book provides thorough coverage of error correcting techniques. It includes essential basic concepts and the latest advances on key topics in design, implementation, and optimization of hardware/software systems for error correction. The book’s chapters are written by internationally recognized experts in this field. Topics include evolution of error correction techniques, industrial user needs, architectures, and design approaches for the most advanced error correcting codes (Polar Codes, Non-Binary LDPC, Product Codes, etc). This book provides access to recent results, and is suitable for graduate students and researchers of mathematics, computer science, and engineering. • Examines how to optimize the architecture of hardware design for error correcting codes; • Presents error correction codes from theory to optimized architecture for the current and the next generation standards; • Provides coverage of industrial user needs advanced error correcting techniques.

  17. Secondary electric power generation with minimum engine bleed

    Science.gov (United States)

    Tagge, G. E.

    1983-01-01

    Secondary electric power generation with minimum engine bleed is discussed. Present and future jet engine systems are compared. The role of auxiliary power units is evaluated. Details of secondary electric power generation systems with and without auxiliary power units are given. Advanced bleed systems are compared with minimum bleed systems. A cost model of ownership is given. The difference in the cost of ownership between a minimum bleed system and an advanced bleed system is given.

  18. Advanced pyrochemical technologies for minimizing nuclear waste

    International Nuclear Information System (INIS)

    Bronson, M.C.; Dodson, K.E.; Riley, D.C.

    1994-01-01

    The Department of Energy (DOE) is seeking to reduce the size of the current nuclear weapons complex and consequently minimize operating costs. To meet this DOE objective, the national laboratories have been asked to develop advanced technologies that take uranium and plutonium, from retired weapons and prepare it for new weapons, long-term storage, and/or final disposition. Current pyrochemical processes generate residue salts and ceramic wastes that require aqueous processing to remove and recover the actinides. However, the aqueous treatment of these residues generates an estimated 100 liters of acidic transuranic (TRU) waste per kilogram of plutonium in the residue. Lawrence Livermore National Laboratory (LLNL) is developing pyrochemical techniques to eliminate, minimize, or more efficiently treat these residue streams. This paper will present technologies being developed at LLNL on advanced materials for actinide containment, reactors that minimize residues, and pyrochemical processes that remove actinides from waste salts

  19. Advances in Retinal Stem Cell Biology

    Directory of Open Access Journals (Sweden)

    Andrea S Viczian

    2013-01-01

    Full Text Available Tremendous progress has been made in recent years to generate retinal cells from pluripotent cell sources. These advances provide hope for those suffering from blindness due to lost retinal cells. Understanding the intrinsic genetic network in model organisms, like fly and frog, has led to a better understanding of the extrinsic signaling pathways necessary for retinal progenitor cell formation in mouse and human cell cultures. This review focuses on the culture methods used by different groups, which has culminated in the generation of laminated retinal tissue from both embryonic and induced pluripotent cells. The review also briefly describes advances made in transplantation studies using donor retinal progenitor and cultured retinal cells.

  20. Advanced TCA BAckplane Tester

    CERN Document Server

    Oltean, Alexandra Dana; PGNet2005

    2005-01-01

    The “Advanced Telecom Computing Architecture” (AdvancedTCA) is a modular standard chassis based system designed to support the needs of carrier class telecommunication applications. It is defined by a set of industry standards under the direction of the PICMG group. One early deployment of the standard technology has been a 10 Gigabit Ethernet switch developed in the framework of the EU funded ESTA project. In order to study the practical aspects of high speed Ethernet switching at 10 Gigabit and above and to validate the signal integrity of the AdvancedTCA backplane, we developed a Backplane Tester. This system is able to run pseudo-random bit sequence (PRBS) traffic at 3.125 Gbps over every link on the AdvancedTCA backplane simultaneously, and to monitor any possible connectivity failure immediately in terms of the link and slot positions inside the chassis. In this paper, we describe the design and the practical architectural hardware and software aspects of the AdvancedTCA Backplane Tester. We also pr...

  1. Advanced fuel chemistry for advanced engines.

    Energy Technology Data Exchange (ETDEWEB)

    Taatjes, Craig A.; Jusinski, Leonard E.; Zador, Judit; Fernandes, Ravi X.; Miller, James A.

    2009-09-01

    Autoignition chemistry is central to predictive modeling of many advanced engine designs that combine high efficiency and low inherent pollutant emissions. This chemistry, and especially its pressure dependence, is poorly known for fuels derived from heavy petroleum and for biofuels, both of which are becoming increasingly prominent in the nation's fuel stream. We have investigated the pressure dependence of key ignition reactions for a series of molecules representative of non-traditional and alternative fuels. These investigations combined experimental characterization of hydroxyl radical production in well-controlled photolytically initiated oxidation and a hybrid modeling strategy that linked detailed quantum chemistry and computational kinetics of critical reactions with rate-equation models of the global chemical system. Comprehensive mechanisms for autoignition generally ignore the pressure dependence of branching fractions in the important alkyl + O{sub 2} reaction systems; however we have demonstrated that pressure-dependent 'formally direct' pathways persist at in-cylinder pressures.

  2. Forest biotechnology advances to support global bioeconomy

    OpenAIRE

    Antoine Harfouche; Sacha Khoury; Francesco Fabbrini; Giuseppe Scarascia Mugnozza

    2015-01-01

    The world is shifting to an innovation economy and forest biotechnology can play a major role in the bio-economy by providing farmers, producers, and consumers with tools that can better advance this transition. First-generation or conventional biofuels are primarily produced from food crops and are therefore limited in their ability to meet challenges for petroleum-product substitution and climate change mitigation, and to overcome the food-versus-fuel dilemma. In the longer term, forest lig...

  3. Advanced Fingerprint Analysis Project Fingerprint Constituents; TOPICAL

    International Nuclear Information System (INIS)

    GM Mong; CE Petersen; TRW Clauss

    1999-01-01

    The work described in this report was focused on generating fundamental data on fingerprint components which will be used to develop advanced forensic techniques to enhance fluorescent detection, and visualization of latent fingerprints. Chemical components of sweat gland secretions are well documented in the medical literature and many chemical techniques are available to develop latent prints, but there have been no systematic forensic studies of fingerprint sweat components or of the chemical and physical changes these substances undergo over time

  4. Recent advances in plant-herbivore interactions

    OpenAIRE

    Burkepile, Deron E.; Parker, John D.

    2017-01-01

    Plant-herbivore interactions shape community dynamics across marine, freshwater, and terrestrial habitats. From amphipods to elephants and from algae to trees, plant-herbivore relationships are the crucial link generating animal biomass (and human societies) from mere sunlight. These interactions are, thus, pivotal to understanding the ecology and evolution of virtually any ecosystem. Here, we briefly highlight recent advances in four areas of plant-herbivore interactions: (1) plant defense t...

  5. Advanced Fingerprint Analysis Project Fingerprint Constituents

    Energy Technology Data Exchange (ETDEWEB)

    GM Mong; CE Petersen; TRW Clauss

    1999-10-29

    The work described in this report was focused on generating fundamental data on fingerprint components which will be used to develop advanced forensic techniques to enhance fluorescent detection, and visualization of latent fingerprints. Chemical components of sweat gland secretions are well documented in the medical literature and many chemical techniques are available to develop latent prints, but there have been no systematic forensic studies of fingerprint sweat components or of the chemical and physical changes these substances undergo over time.

  6. Magnetohydrodynamic (MHD) power generation

    International Nuclear Information System (INIS)

    Chandra, Avinash

    1980-01-01

    The concept of MHD power generation, principles of operation of the MHD generator, its design, types, MHD generator cycles, technological problems to be overcome, the current state of the art in USA and USSR are described. Progress of India's experimental 5 Mw water-gas fired open cycle MHD power generator project is reported in brief. (M.G.B.)

  7. Minding the Generation Gap

    Science.gov (United States)

    Field, John

    2011-01-01

    Generational conflict is back. After years of relative silence, and mutual ignorance, the young and old are once more at war. With youth unemployment high on the political agenda, the fortunes of the "jobless generation" are being contrasted with those of the "golden generation" of baby boomers, but is one generation really…

  8. Work Values across Generations

    Science.gov (United States)

    Hansen, Jo-Ida C.; Leuty, Melanie E.

    2012-01-01

    Mainstream publication discussions of differences in generational cohorts in the workplace suggest that individuals of more recent generations, such as Generation X and Y, have different work values than do individuals of the Silent and Baby Boom generations. Although extant research suggests that age may influence work values, few of the…

  9. Talkin' 'bout My Generation

    Science.gov (United States)

    Rickes, Persis C.

    2010-01-01

    The monikers are many: (1) "Generation Y"; (2) "Echo Boomers"; (3) "GenMe"; (4) the "Net Generation"; (5) "RenGen"; and (6) "Generation Next". One name that appears to be gaining currency is "Millennials," perhaps as a way to better differentiate the current generation from its…

  10. ADVANCED CUTTINGS TRANSPORT STUDY

    Energy Technology Data Exchange (ETDEWEB)

    Stefan Miska; Troy Reed; Ergun Kuru

    2004-09-30

    The Advanced Cuttings Transport Study (ACTS) was a 5-year JIP project undertaken at the University of Tulsa (TU). The project was sponsored by the U.S. Department of Energy (DOE) and JIP member companies. The objectives of the project were: (1) to develop and construct a new research facility that would allow three-phase (gas, liquid and cuttings) flow experiments under ambient and EPET (elevated pressure and temperature) conditions, and at different angle of inclinations and drill pipe rotation speeds; (2) to conduct experiments and develop a data base for the industry and academia; and (3) to develop mechanistic models for optimization of drilling hydraulics and cuttings transport. This project consisted of research studies, flow loop construction and instrumentation development. Following a one-year period for basic flow loop construction, a proposal was submitted by TU to the DOE for a five-year project that was organized in such a manner as to provide a logical progression of research experiments as well as additions to the basic flow loop. The flow loop additions and improvements included: (1) elevated temperature capability; (2) two-phase (gas and liquid, foam etc.) capability; (3) cuttings injection and removal system; (4) drill pipe rotation system; and (5) drilling section elevation system. In parallel with the flow loop construction, hydraulics and cuttings transport studies were preformed using drilling foams and aerated muds. In addition, hydraulics and rheology of synthetic drilling fluids were investigated. The studies were performed under ambient and EPET conditions. The effects of temperature and pressure on the hydraulics and cuttings transport were investigated. Mechanistic models were developed to predict frictional pressure loss and cuttings transport in horizontal and near-horizontal configurations. Model predictions were compared with the measured data. Predominantly, model predictions show satisfactory agreements with the measured data. As a

  11. ADVANCED WORKER PROTECTION SYSTEM

    International Nuclear Information System (INIS)

    Judson Hedgehock

    2001-01-01

    From 1993 to 2000, OSS worked under a cost share contract from the Department of Energy (DOE) to develop an Advanced Worker Protection System (AWPS). The AWPS is a protective ensemble that provides the user with both breathing air and cooling for a NIOSH-rated duration of two hours. The ensemble consists of a liquid air based backpack, a Liquid Cooling Garment (LCG), and an outer protective garment. The AWPS project was divided into two phases. During Phase 1, OSS developed and tested a full-scale prototype AWPS. The testing showed that workers using the AWPS could work twice as long as workers using a standard SCBA. The testing also provided performance data on the AWPS in different environments that was used during Phase 2 to optimize the design. During Phase 1, OSS also performed a life-cycle cost analysis on a representative clean up effort. The analysis indicated that the AWPS could save the DOE millions of dollars on D and D activities and improve the health and safety of their workers. During Phase 2, OSS worked to optimize the AWPS design to increase system reliability, to improve system performance and comfort, and to reduce the backpack weight and manufacturing costs. To support this design effort, OSS developed and tested several different generations of prototype units. Two separate successful evaluations of the ensemble were performed by the International Union of Operation Engineers (IUOE). The results of these evaluations were used to drive the design. During Phase 2, OSS also pursued certifying the AWPS with the applicable government agencies. The initial intent during Phase 2 was to finalize the design and then to certify the system. OSS and Scott Health and Safety Products teamed to optimize the AWPS design and then certify the system with the National Institute of Occupational Health and Safety (NIOSH). Unfortunately, technical and programmatic difficulties prevented us from obtaining NIOSH certification. Despite the inability of NIOSH to certify

  12. ADVANCED WORKER PROTECTION SYSTEM

    Energy Technology Data Exchange (ETDEWEB)

    Judson Hedgehock

    2001-03-16

    From 1993 to 2000, OSS worked under a cost share contract from the Department of Energy (DOE) to develop an Advanced Worker Protection System (AWPS). The AWPS is a protective ensemble that provides the user with both breathing air and cooling for a NIOSH-rated duration of two hours. The ensemble consists of a liquid air based backpack, a Liquid Cooling Garment (LCG), and an outer protective garment. The AWPS project was divided into two phases. During Phase 1, OSS developed and tested a full-scale prototype AWPS. The testing showed that workers using the AWPS could work twice as long as workers using a standard SCBA. The testing also provided performance data on the AWPS in different environments that was used during Phase 2 to optimize the design. During Phase 1, OSS also performed a life-cycle cost analysis on a representative clean up effort. The analysis indicated that the AWPS could save the DOE millions of dollars on D and D activities and improve the health and safety of their workers. During Phase 2, OSS worked to optimize the AWPS design to increase system reliability, to improve system performance and comfort, and to reduce the backpack weight and manufacturing costs. To support this design effort, OSS developed and tested several different generations of prototype units. Two separate successful evaluations of the ensemble were performed by the International Union of Operation Engineers (IUOE). The results of these evaluations were used to drive the design. During Phase 2, OSS also pursued certifying the AWPS with the applicable government agencies. The initial intent during Phase 2 was to finalize the design and then to certify the system. OSS and Scott Health and Safety Products teamed to optimize the AWPS design and then certify the system with the National Institute of Occupational Health and Safety (NIOSH). Unfortunately, technical and programmatic difficulties prevented us from obtaining NIOSH certification. Despite the inability of NIOSH to certify

  13. Advanced flip chip packaging

    CERN Document Server

    Lai, Yi-Shao; Wong, CP

    2013-01-01

    Advanced Flip Chip Packaging presents past, present and future advances and trends in areas such as substrate technology, material development, and assembly processes. Flip chip packaging is now in widespread use in computing, communications, consumer and automotive electronics, and the demand for flip chip technology is continuing to grow in order to meet the need for products that offer better performance, are smaller, and are environmentally sustainable. This book also: Offers broad-ranging chapters with a focus on IC-package-system integration Provides viewpoints from leading industry executives and experts Details state-of-the-art achievements in process technologies and scientific research Presents a clear development history and touches on trends in the industry while also discussing up-to-date technology information Advanced Flip Chip Packaging is an ideal book for engineers, researchers, and graduate students interested in the field of flip chip packaging.

  14. Advanced Magnetic Nanostructures

    CERN Document Server

    Sellmyer, David

    2006-01-01

    Advanced Magnetic Nanostructures is devoted to the fabrication, characterization, experimental investigation, theoretical understanding, and utilization of advanced magnetic nanostructures. Focus is on various types of 'bottom-up' and 'top-down' artificial nanostructures, as contrasted to naturally occurring magnetic nanostructures, such as iron-oxide inclusions in magnetic rocks, and to structures such as perfect thin films. Chapter 1 is an introduction into some basic concepts, such as the definitions of basic magnetic quantities. Chapters 2-4 are devoted to the theory of magnetic nanostructures, Chapter 5 deals with the characterization of the structures, and Chapters 6-10 are devoted to specific systems. Applications of advanced magnetic nanostructures are discussed in Chapters11-15 and, finally, the appendix lists and briefly discusses magnetic properties of typical starting materials. Industrial and academic researchers in magnetism and related areas such as nanotechnology, materials science, and theore...

  15. Advanced materials-2005

    International Nuclear Information System (INIS)

    Farooque, M.; Rizvi, S.A.; Mirza, J.A.

    2005-01-01

    The 9. International Symposium on Advanced Materials (ISAM) was held from 19-22 September, 2005. This popular biennial event is one of the prime international forums in South Asia where material scientists and engineers can keep abreast with recent technologies involving advanced structural and functional materials. The technical committee of ISAM received 213 papers, 49 from abroad 164 from within the country. These papers were submitted in response to five important topics; i) Processing, Production and Developments, ii) Surface Engineering, iii) Phase Transformation and Characterization, iv) Advances in Magnetic Materials and v) Reliability and Life Assessment. The proceedings of the 9. ISAM consists of 108 reviewed papers. This symposium provided an ideal opportunity for exchange of information amongst scientists, engineers, and researchers. (A.B.)

  16. Advances in business ICT

    CERN Document Server

    Pełech-Pilichowski, Tomasz

    2014-01-01

    Futurists and scientists alike profess the coming of a new era in the history – the knowledge era. The notion of knowledge is as old as humans’ self-consciousness, but new challenges appear. The meaning of the word “knowledge” is changing from cognitive notion to a technical term denoting a structured economic resource to be actively managed. This contributed volume is a result of vivid and extremely valuable discussions held at 3rd International Workshop on Advances in Business ICT (ABICT) in Wrocław, Poland, September 9-12, 2012. The workshop focused on Advances in Business ICT approached from a multidisciplinary perspective. It provided an international forum for scientists/experts from academia and industry to discuss and exchange current results, applications, new ideas of ongoing research and experience on all aspects of Business Intelligence. ABICT has also been an opportunity to demonstrate different ideas and tools for developing and supporting organizational creativity, as well as advances ...

  17. Advanced Hydrogen Turbine Development

    Energy Technology Data Exchange (ETDEWEB)

    Marra, John [Siemens Energy, Inc., Orlando, FL (United States)

    2015-09-30

    Under the sponsorship of the U.S. Department of Energy (DOE) National Energy Technology Laboratories, Siemens has completed the Advanced Hydrogen Turbine Development Program to develop an advanced gas turbine for incorporation into future coal-based Integrated Gasification Combined Cycle (IGCC) plants. All the scheduled DOE Milestones were completed and significant technical progress was made in the development of new technologies and concepts. Advanced computer simulations and modeling, as well as subscale, full scale laboratory, rig and engine testing were utilized to evaluate and select concepts for further development. Program Requirements of: A 3 to 5 percentage point improvement in overall plant combined cycle efficiency when compared to the reference baseline plant; 20 to 30 percent reduction in overall plant capital cost when compared to the reference baseline plant; and NOx emissions of 2 PPM out of the stack. were all met. The program was completed on schedule and within the allotted budget

  18. Advancement & Promotion Review: 2003

    CERN Multimedia

    2003-01-01

    Advancement, exceptional advancement and promotion decisions were made at the end of June, following the procedures published in Weekly Bulletin No. 13/2003. These decisions were included, where applicable, in the salaries for the month of July 2003. The award of the periodic step was communicated to staff by the salary shown on the July salary slip. All other decisions are communicated by separate notification. The names of staff receiving exceptional advancements or promotions are now published on the HR Division website and are accessible for consultation only at the following address: http://cern.ch/hr-div/internal/personnel/advlist_2003.asp It is recalled that change of career path proposals submitted to the Technical Engineers and Administrative Careers Committee (TEACC) or to Human Resources Division are being examined with a view to preparing the latters' recommendations by the end of September 2003. Final decisions will be applied retroactively to 1 July 2003. Human Resources Division Tel:...

  19. ADVANCEMENT & PROMOTION REVIEW: 2002

    CERN Multimedia

    2002-01-01

    Advancement, exceptional advancement and promotion decisions were made at the beginning of July, under the new career structure scheme and following the procedures published in Weekly Bulletin No. 11/2002. These decisions were included, where applicable, in the salaries for the month of July 2002. The award of the periodic step was communicated to staff by the salary shown on the July salary slip. All other decisions are communicated by separate notification. The names of staff receiving exceptional advancements or promotions will be published this year on the HR Division website and are accessible for consultation only at the following address : http://cern.ch/hr-div/internal/personnel/advlist.asp It is recalled that change of career path proposals submitted to the Technical Engineers and Administrative Careers Committee (TEACC) or to Human Resources Division are being examined with a view to preparing the latters' recommendations by the end of September 2002. Final decisions will be applied retroactivel...

  20. Advances in the Ignitor program

    International Nuclear Information System (INIS)

    Coppi, B.; Airoldi, A.; Alladio, F.; Bombarda, F.; Capriccioli, A.; Cenacchi, G.; Coletti, A.; Coletti, R.; Cucchiaro, A.; Detragiache, P.; Frattolillo, A.; Frosi, P.; Galbiati, L.; Lucchini, F.; Maddaluno, G.; Migliori, S.; Pierattini, S.; Pizzuto, A.; Ramogida, G.; Roccella, M.; Romanelli, M.; Santinelli, M.; Sassi, M.; Bianchi, A.; Parodi, B.; Maggiora, R.; Sestero, A.; Subba, F.; Zanino, R.

    2005-01-01

    The most significant recent advances that have been made within the Ignitor program are described. For physics, these involve the analysis of the confinement properties of plasmas produced in recent experiments with peaked density profiles relevant to Ignitor, the characterization of the regimes with double X-point configurations that Ignitor can generate, and the study of oscillatory states for the plasma pressure near ignition that can be obtained by both external and internal forms of control. On the engineering side, the second generation prototypes of the toroidal magnet plates that have been constructed are described. The completion of the design of the plasma chamber that withstands the estimated disruption forces, of the first wall system, including Mo tiles and associated supporting plates, and of the remote handling system is reported. Other relevant R and D activities (i.e. construction of a fast pellet injector) are being carried out. The design of all elements of the poloidal field system has been re-optimized. The analysis of the connection of Ignitor to a node of the European grid has been completed with positive results and official authorization. The set of currents in the machine coils, for a plasma current pulse of 11 MA, that minimizes the requirements of the machine electrical power supply system has been identified. (author)