WorldWideScience

Sample records for advance stringent control

  1. Stringent control of FLP recombinase in Escherichia coli.

    Science.gov (United States)

    Bowden, Steven D; Palani, Nagendra P; Libourel, Igor G L

    2017-02-01

    Site specific recombinases are invaluable tools in molecular biology, and are emerging as powerful recorders of cellular events in synthetic biology. We have developed a stringently controlled FLP recombinase system in Escherichia coli using an arabinose inducible promoter combined with a weak ribosome binding site.

  2. Electricity versus hydrogen for passenger cars under stringent climate change control

    NARCIS (Netherlands)

    Rösler, H.; van der Zwaan, B.; Keppo, I.; Bruggink, J.

    2014-01-01

    In this article we analyze how passenger car transportation in Europe may change this century under permanent high oil prices and stringent climate control policy. We focus on electricity and hydrogen as principal candidate energy carriers, because these two options are increasingly believed to

  3. Electricity versus hydrogen for passenger cars under stringent climate change control

    NARCIS (Netherlands)

    Rösler, H.; van der Zwaan, B.; Keppo, I.; Bruggink, J.

    2014-01-01

    In this article we analyze how passenger car transportation in Europe may change this century under permanent high oil prices and stringent climate control policy. We focus on electricity and hydrogen as principal candidate energy carriers, because these two options are increasingly believed to beco

  4. Bacterial Abscess Formation Is Controlled by the Stringent Stress Response and Can Be Targeted Therapeutically.

    Science.gov (United States)

    Mansour, Sarah C; Pletzer, Daniel; de la Fuente-Núñez, César; Kim, Paul; Cheung, Gordon Y C; Joo, Hwang-Soo; Otto, Michael; Hancock, Robert E W

    2016-10-01

    Cutaneous abscess infections are difficult to treat with current therapies and alternatives to conventional antibiotics are needed. Understanding the regulatory mechanisms that govern abscess pathology should reveal therapeutic interventions for these recalcitrant infections. Here we demonstrated that the stringent stress response employed by bacteria to cope and adapt to environmental stressors was essential for the formation of lesions, but not bacterial growth, in a methicillin resistant Staphylococcus aureus (MRSA) cutaneous abscess mouse model. To pharmacologically confirm the role of the stringent response in abscess formation, a cationic peptide that causes rapid degradation of the stringent response mediator, guanosine tetraphosphate (ppGpp), was employed. The therapeutic application of this peptide strongly inhibited lesion formation in mice infected with Gram-positive MRSA and Gram-negative Pseudomonas aeruginosa. Overall, we provide insights into the mechanisms governing abscess formation and a paradigm for treating multidrug resistant cutaneous abscesses.

  5. City-specific vehicle emission control strategies to achieve stringent emission reduction targets in China's Yangtze River Delta region.

    Science.gov (United States)

    Zhang, Shaojun; Wu, Ye; Zhao, Bin; Wu, Xiaomeng; Shu, Jiawei; Hao, Jiming

    2017-01-01

    The Yangtze River Delta (YRD) region is one of the most prosperous and densely populated regions in China and is facing tremendous pressure to mitigate vehicle emissions and improve air quality. Our assessment has revealed that mitigating vehicle emissions of NOx would be more difficult than reducing the emissions of other major vehicular pollutants (e.g., CO, HC and PM2.5) in the YRD region. Even in Shanghai, where the emission control implemented are more stringent than in Jiangsu and Zhejiang, we observed little to no reduction in NOx emissions from 2000 to 2010. Emission-reduction targets for HC, NOx and PM2.5 are determined using a response surface modeling tool for better air quality. We design city-specific emission control strategies for three vehicle-populated cities in the YRD region: Shanghai and Nanjing and Wuxi in Jiangsu. Our results indicate that even if stringent emission control consisting of the Euro 6/VI standards, the limitation of vehicle population and usage, and the scrappage of older vehicles is applied, Nanjing and Wuxi will not be able to meet the NOx emissions target by 2020. Therefore, additional control measures are proposed for Nanjing and Wuxi to further mitigate NOx emissions from heavy-duty diesel vehicles.

  6. Stringent Expression Control of Pathogenic R-body Production in Legume Symbiont Azorhizobium caulinodans.

    Science.gov (United States)

    Matsuoka, Jun-Ichi; Ishizuna, Fumiko; Kurumisawa, Keigo; Morohashi, Kengo; Ogawa, Tetsuhiro; Hidaka, Makoto; Saito, Katsuharu; Ezawa, Tatsuhiro; Aono, Toshihiro

    2017-07-25

    R bodies are insoluble large polymers consisting of small proteins encoded by reb genes and are coiled into cylindrical structures in bacterial cells. They were first discovered in Caedibacter species, which are obligate endosymbionts of paramecia. Caedibacter confers a killer trait on the host paramecia. R-body-producing symbionts are released from their host paramecia and kill symbiont-free paramecia after ingestion. The roles of R bodies have not been explained in bacteria other than CaedibacterAzorhizobium caulinodans ORS571, a microsymbiont of the legume Sesbania rostrata, carries a reb operon containing four reb genes that are regulated by the repressor PraR. Herein, deletion of the praR gene resulted in R-body formation and death of host plant cells. The rebR gene in the reb operon encodes an activator. Three PraR binding sites and a RebR binding site are present in the promoter region of the reb operon. Expression analyses using strains with mutations within the PraR binding site and/or the RebR binding site revealed that PraR and RebR directly control the expression of the reb operon and that PraR dominantly represses reb expression. Furthermore, we found that the reb operon is highly expressed at low temperatures and that 2-oxoglutarate induces the expression of the reb operon by inhibiting PraR binding to the reb promoter. We conclude that R bodies are toxic not only in paramecium symbiosis but also in relationships between other bacteria and eukaryotic cells and that R-body formation is controlled by environmental factors.IMPORTANCECaedibacter species, which are obligate endosymbiotic bacteria of paramecia, produce R bodies, and R-body-producing endosymbionts that are released from their hosts are pathogenic to symbiont-free paramecia. Besides Caedibacter species, R bodies have also been observed in a few free-living bacteria, but the significance of R-body production in these bacteria is still unknown. Recent advances in genome sequencing technologies

  7. Synthetic dual-input mammalian genetic circuits enable tunable and stringent transcription control by chemical and light.

    Science.gov (United States)

    Chen, Xianjun; Li, Ting; Wang, Xue; Du, Zengmin; Liu, Renmei; Yang, Yi

    2016-04-01

    Programmable transcription factors can enable precise control of gene expression triggered by a chemical inducer or light. To obtain versatile transgene system with combined benefits of a chemical inducer and light inducer, we created various chimeric promoters through the assembly of different copies of the tet operator and Gal4 operator module, which simultaneously responded to a tetracycline-responsive transcription factor and a light-switchable transactivator. The activities of these chimeric promoters can be regulated by tetracycline and blue light synergistically or antagonistically. Further studies of the antagonistic genetic circuit exhibited high spatiotemporal resolution and extremely low leaky expression, which therefore could be used to spatially and stringently control the expression of highly toxic protein Diphtheria toxin A for light regulated gene therapy. When transferring plasmids engineered for the gene switch-driven expression of a firefly luciferase (Fluc) into mice, the Fluc expression levels of the treated animals directly correlated with the tetracycline and light input program. We suggest that dual-input genetic circuits using TET and light that serve as triggers to achieve expression profiles may enable the design of robust therapeutic gene circuits for gene- and cell-based therapies.

  8. Stringent control of cytoplasmic Ca2+ in guard cells of intact plants compared to their counterparts in epidermal strips or guard cell protoplasts.

    Science.gov (United States)

    Levchenko, V; Guinot, D R; Klein, M; Roelfsema, M R G; Hedrich, R; Dietrich, P

    2008-01-01

    Cytoplasmic calcium elevations, transients, and oscillations are thought to encode information that triggers a variety of physiological responses in plant cells. Yet Ca(2+) signals induced by a single stimulus vary, depending on the physiological state of the cell and experimental conditions. We compared Ca(2+) homeostasis and stimulus-induced Ca(2+) signals in guard cells of intact plants, epidermal strips, and isolated protoplasts. Single-cell ratiometric imaging with the Ca(2+)-sensitive dye Fura 2 was applied in combination with electrophysiological recordings. Guard cell protoplasts were loaded with Fura 2 via a patch pipette, revealing a cytoplasmic free Ca(2+) concentration of around 80 nM at -47 mV. Upon hyperpolarization of the plasma membrane to -107 mV, the Ca(2+) concentration increased to levels exceeding 400 nM. Intact guard cells were able to maintain much lower cytoplasmic free Ca(2+) concentrations at hyperpolarized potentials, the average concentration at -100 mV was 183 and 90 nM in epidermal strips and intact plants, respectively. Further hyperpolarization of the plasma membrane to -160 mV induced a sustained rise of the guard cell cytoplasmic Ca(2+) concentration, which slowly returned to the prestimulus level in intact plants but not in epidermal strips. Our results show that cytoplasmic Ca(2+) concentrations are stringently controlled in guard cells of intact plants but become increasingly more sensitive to changes in the plasma membrane potential in epidermal strips and isolated protoplasts.

  9. Advanced Control Engineering

    DEFF Research Database (Denmark)

    Zhou, Jianjun

    1999-01-01

    This book is developed as a textbook for the course Advanced Control Engineering. The book is intended for students in mechanical engineering and its aim is to provide an understanding of modern control theory as well as methodologies and applications for state space modeling and design....... For this reason, the book puts emphasis on the state-space approach. The main contents of the book includes state-space representation of dynamic systems, analysis of linear control systems, feedback control and observer design. Both continuous-time and discrete-time systems have been addressed in this book....

  10. Advanced Wavefront Control Techniques

    Energy Technology Data Exchange (ETDEWEB)

    Olivier, S S; Brase, J M; Avicola, K; Thompson, C A; Kartz, M W; Winters, S; Hartley, R; Wihelmsen, J; Dowla, F V; Carrano, C J; Bauman, B J; Pennington, D M; Lande, D; Sawvel, R M; Silva, D A; Cooke, J B; Brown, C G

    2001-02-21

    this project, work was performed in four areas (1) advanced modeling tools for deformable mirrors (2) low-order wavefront correctors with Alvarez lenses, (3) a direct phase measuring heterdyne wavefront sensor, and (4) high-spatial-frequency wavefront control using spatial light modulators.

  11. Advances in Adaptive Control Methods

    Science.gov (United States)

    Nguyen, Nhan

    2009-01-01

    This poster presentation describes recent advances in adaptive control technology developed by NASA. Optimal Control Modification is a novel adaptive law that can improve performance and robustness of adaptive control systems. A new technique has been developed to provide an analytical method for computing time delay stability margin for adaptive control systems.

  12. Advanced Control of Turbofan Engines

    CERN Document Server

    Richter, Hanz

    2012-01-01

    Advanced Control of Turbofan Engines describes the operational performance requirements of turbofan (commercial)engines from a controls systems perspective, covering industry-standard methods and research-edge advances. This book allows the reader to design controllers and produce realistic simulations using public-domain software like CMAPSS: Commercial Modular Aero-Propulsion System Simulation, whose versions are released to the public by NASA. The scope of the book is centered on the design of thrust controllers for both steady flight and transient maneuvers. Classical control theory is not dwelled on, but instead an introduction to general undergraduate control techniques is provided. This book also: Develops a thorough understanding of the challenges associated with engine operability from a control systems perspective, describing performance demands and operational constraints into the framework and language of modern control theory Presents solid theoretical support for classical and advanced engine co...

  13. Advanced AC Motor Control

    Energy Technology Data Exchange (ETDEWEB)

    Kazmierkowski, M.P. [Institute of Control and Industrial Electronics, Warsaw University of Technology, Warszawa (Poland)

    1997-12-31

    In this paper a review of control methods for high performance PWM inverter-fed induction motor drives is presented. Starting from the description of an induction motor by the help of the space vectors, three basic control strategic are discussed. As first, the most popular Field Oriented Control (FOC) is described. Secondly, the Direct Torque and Flux vector Control (DTFC) method, which - in contrast to FOC - depart from idea of coordinate transformation and analogy with DC motor, is briefly characterized. The last group is based on Feedback Linearization Control (FLC) and can be easy combined with sliding mode control. The simulation and experimental oscillograms that illustrate the performance of the discussed control strategies are shown. (orig.) 35 refs.

  14. ADVANCED SULFUR CONTROL CONCEPTS

    Energy Technology Data Exchange (ETDEWEB)

    Apostolos A. Nikolopoulos; Santosh K. Gangwal; William J. McMichael; Jeffrey W. Portzer

    2003-01-01

    Conventional sulfur removal in integrated gasification combined cycle (IGCC) power plants involves numerous steps: COS (carbonyl sulfide) hydrolysis, amine scrubbing/regeneration, Claus process, and tail-gas treatment. Advanced sulfur removal in IGCC systems involves typically the use of zinc oxide-based sorbents. The sulfides sorbent is regenerated using dilute air to produce a dilute SO{sub 2} (sulfur dioxide) tail gas. Under previous contracts the highly effective first generation Direct Sulfur Recovery Process (DSRP) for catalytic reduction of this SO{sub 2} tail gas to elemental sulfur was developed. This process is currently undergoing field-testing. In this project, advanced concepts were evaluated to reduce the number of unit operations in sulfur removal and recovery. Substantial effort was directed towards developing sorbents that could be directly regenerated to elemental sulfur in an Advanced Hot Gas Process (AHGP). Development of this process has been described in detail in Appendices A-F. RTI began the development of the Single-step Sulfur Recovery Process (SSRP) to eliminate the use of sorbents and multiple reactors in sulfur removal and recovery. This process showed promising preliminary results and thus further process development of AHGP was abandoned in favor of SSRP. The SSRP is a direct Claus process that consists of injecting SO{sub 2} directly into the quenched coal gas from a coal gasifier, and reacting the H{sub 2}S-SO{sub 2} mixture over a selective catalyst to both remove and recover sulfur in a single step. The process is conducted at gasifier pressure and 125 to 160 C. The proposed commercial embodiment of the SSRP involves a liquid phase of molten sulfur with dispersed catalyst in a slurry bubble-column reactor (SBCR).

  15. Advances in robust fractional control

    CERN Document Server

    Padula, Fabrizio

    2015-01-01

    This monograph presents design methodologies for (robust) fractional control systems. It shows the reader how to take advantage of the superior flexibility of fractional control systems compared with integer-order systems in achieving more challenging control requirements. There is a high degree of current interest in fractional systems and fractional control arising from both academia and industry and readers from both milieux are catered to in the text. Different design approaches having in common a trade-off between robustness and performance of the control system are considered explicitly. The text generalizes methodologies, techniques and theoretical results that have been successfully applied in classical (integer) control to the fractional case. The first part of Advances in Robust Fractional Control is the more industrially-oriented. It focuses on the design of fractional controllers for integer processes. In particular, it considers fractional-order proportional-integral-derivative controllers, becau...

  16. A stringent dual control system overseeing transcription and activity of the Cre recombinase for the liver-specific conditional gene knock-out mouse model

    Institute of Scientific and Technical Information of China (English)

    Yu Wu; Yinghua He; Hongyu Zhang; Xinlan Dai; Xiaoyu Zhou; Jun Gu; Guan Wang; Jingde Zhu

    2008-01-01

    Liver cancer is one of the most threatening diseases in Chinese population. Just like in other tissues, tumor initiation and development in liver involve multiple steps of genetic and epigenetic alterations with several unknown details. However, unlike in other tissues, a tis- sue specific inducible Cre recombinase system that allows temporal and spatial deletion of a target DNA fragment is still not available for in vivo functional gene annotation in hepatocytes. In our pursuit to establish such a mouse model, we designed a dual inducible Cre transgene system and tested it in cultured cells. By combining a CCAAT/enhancer binding protein β (C/EBP β) promoter derived Tet-off expression system and the estrogen receptor (ER) mediated functional control, we show a desirable profile of both hepatocyte-specificity and regulability of the Cre expression in a series of critical assessments in the cell culture system, which provides confidence in continua- tion of our ongoing pursuit in mouse.

  17. Advanced Thermal Control Flight Experiment.

    Science.gov (United States)

    Kirkpatrick, J. P.; Brennan, P. J.

    1973-01-01

    The advanced Thermal Control Flight Experiment on the Applications Technology Satellite (ATS-F) will evaluate, for the first time in a space environment, the performance of a feedback-controlled variable conductance heat pipe and a heat pipe thermal diode. In addition, the temperature control aspects of a phase-change material (PCM) will be demonstrated. The methanol/stainless steel feedback-controlled heat pipe uses helium control gas that is stored in a wicked reservoir. This reservoir is electrically heated through a solid state controller that senses the temperature of the heat source directly. The ammonia/stainless steel diode heat pipe uses excess liquid to block heat transfer in the reverse direction. The PCM is octadecane. Design tradeoffs, fabrication problems, and performance during qualification and flight acceptance tests are discussed.

  18. Advanced gray rod control assembly

    Energy Technology Data Exchange (ETDEWEB)

    Drudy, Keith J; Carlson, William R; Conner, Michael E; Goldenfield, Mark; Hone, Michael J; Long, Jr., Carroll J; Parkinson, Jerod; Pomirleanu, Radu O

    2013-09-17

    An advanced gray rod control assembly (GRCA) for a nuclear reactor. The GRCA provides controlled insertion of gray rod assemblies into the reactor, thereby controlling the rate of power produced by the reactor and providing reactivity control at full power. Each gray rod assembly includes an elongated tubular member, a primary neutron-absorber disposed within the tubular member said neutron-absorber comprising an absorber material, preferably tungsten, having a 2200 m/s neutron absorption microscopic capture cross-section of from 10 to 30 barns. An internal support tube can be positioned between the primary absorber and the tubular member as a secondary absorber to enhance neutron absorption, absorber depletion, assembly weight, and assembly heat transfer characteristics.

  19. Advanced controls for light sources

    Science.gov (United States)

    Biedron, S. G.; Edelen, A. L.; Milton, S. V.

    2016-09-01

    We present a summary of our team's recent efforts in developing adaptive, artificial intelligence-inspired techniques specifically to address several control challenges that arise in machines/systems including those in particle accelerator systems. These techniques can readily be adapted to other systems such as lasers, beamline optics, etc… We are not at all suggesting that we create an autonomous system, but create a system with an intelligent control system, that can continually use operational data to improve itself and combines both traditional and advanced techniques. We believe that the system performance and reliability can be increased based on our findings. Another related point is that the controls sub-system of an overall system is usually not the heart of the system architecture or design process. More bluntly, often times all of the peripheral systems are considered as secondary to the main system components in the architecture design process because it is assumed that the controls system will be able to "fix" challenges found later with the sub-systems for overall system operation. We will show that this is not always the case and that it took an intelligent control application to overcome a sub-system's challenges. We will provide a recent example of such a "fix" with a standard controller and with an artificial intelligence-inspired controller. A final related point to be covered is that of system adaptation for requirements not original to a system's original design.

  20. Advanced Emissions Control Development Program

    Energy Technology Data Exchange (ETDEWEB)

    A.P.Evans; K.E. Redinger; M.J. Holmes

    1998-04-01

    The objective of the Advanced Emissions Control Development Program (AECDP) is to develop practical, cost-effective strategies for reducing the emissions of air toxics from coal-fired boilers. Ideally, the project aim is to effectively control air toxic emissions through the use of conventional flue gas cleanup equipment such as electrostatic precipitators (ESPS), fabric filters (baghouse), and wet flue gas desulfurization. Development work to date has concentrated on the capture of mercury, other trace metals, fine particulate and hydrogen chloride. Following the construction and evaluation of a representative air toxics test facility in Phase I, Phase II focused on the evaluation of mercury and several other air toxics emissions. The AECDP is jointly funded by the United States Department of Energy's Federal Energy Technology Center (DOE), the Ohio Coal Development Office within the Ohio Department of Development (oCDO), and Babcock& Wilcox-a McDermott company (B&W).

  1. Advanced Light Source control system

    Energy Technology Data Exchange (ETDEWEB)

    Magyary, S.; Chin, M.; Cork, C.; Fahmie, M.; Lancaster, H.; Molinari, P.; Ritchie, A.; Robb, A.; Timossi, C.

    1989-03-01

    The Advanced Light Source (ALS) is a third generation 1--2 GeV synchrotron radiation source designed to provide ports for 60 beamlines. It uses a 50 MeV electron linac and 1.5 GeV, 1 Hz, booster synchrotron for injection into a 1--2 GeV storage ring. Interesting control problems are created because of the need for dynamic closed beam orbit control to eliminate interaction between the ring tuning requirements and to minimize orbit shifts due to ground vibrations. The extremely signal sensitive nature of the experiments requires special attention to the sources of electrical noise. These requirements have led to a control system design which emphasizes connectivity at the accelerator equipment end and a large I/O bandwidth for closed loop system response. Not overlooked are user friendliness, operator response time, modeling, and expert system provisions. Portable consoles are used for local operation of machine equipment. Our solution is a massively parallel system with >120 Mbits/sec I/O bandwidth and >1500 Mips computing power. At the equipment level connections are made using over 600 powerful Intelligent Local Controllers (ILC-s) mounted in 3U size Eurocard slots using fiber-optic cables between rack locations. In the control room, personal computers control and display all machine variables at a 10 Hz rate including the scope signals which are collected though the control system. Commercially available software and industry standards are used extensively. Particular attention is paid to reliability, maintainability and upgradeability. 10 refs., 11 figs.

  2. Evaluation of robotically controlled advanced endoscopic instruments

    NARCIS (Netherlands)

    Reilink, Rob; Kappers, Astrid M.L.; Stramigioli, Stefano; Misra, Sarthak

    Background Advanced flexible endoscopes and instruments with multiple degrees of freedom enable physicians to perform challenging procedures such as the removal of large sections of mucosal tissue. However, these advanced endoscopes are difficult to control and require several physicians to

  3. The Sinorhizobium meliloti stringent response affects multiple aspects of symbiosis.

    Science.gov (United States)

    Wells, Derek H; Long, Sharon R

    2002-03-01

    Sinorhizobium meliloti and host legumes enter into a nitrogen-fixing, symbiotic relationship triggered by an exchange of signals between bacteria and plant. S. meliloti produces Nod factor, which elicits the formation of nodules on plant roots, and succinoglycan, an exopolysaccharide that allows for bacterial invasion and colonization of the host. The biosynthesis of these molecules is well defined, but the specific regulation of these compounds is not completely understood. Bacteria control complex regulatory networks by the production of ppGpp, the effector molecule of the stringent response, which induces physiological change in response to adverse growth conditions and can also control bacterial development and virulence. Through detailed analysis of an S. meliloti mutant incapable of producing ppGpp, we show that the stringent response is required for nodule formation and regulates the production of succinoglycan. Although it remains unknown whether these phenotypes are connected, we have isolated suppressor strains that restore both defects and potentially identify key downstream regulatory genes. These results indicate that the S. meliloti stringent response has roles in both succinoglycan production and nodule formation and, more importantly, that control of bacterial physiology in response to the plant and surrounding environment is critical to the establishment of a successful symbiosis.

  4. Satisfying Stringent Requirements for Fine Attitude Control of Hypersonic Cruise Vehicle (HCV)%高超声速巡航飞行器振动建模及精细姿态控制

    Institute of Scientific and Technical Information of China (English)

    孟中杰; 黄攀峰; 闫杰

    2011-01-01

    Aim. The introduction of the full paper reviews a number of papers in the open literature and then out-lines the research in this paper, which is explained in sections 1, 2 and 3. Taking the longitudinal channel of a HCV for example, section 1 analyzes the impact of elastic vibration on its flight control system. Section 2 establishes the elastic aerodynamic model of the HCV by giving eqs. (9) and ( 11 ). The core of section 3 consists of:(t) we reduce the fine attitude control of HCV to the fine control of the inlet local angle of attack (AOA) of a scramjet; (2) considering that body/engine coupling and aerodynamic heating cause the large-scale perturbation of the aerodynamic parameters and model parameters, we design the fine attitude control system by using the H ∞ control theory, which is shown by the block diagram in Fig. 2; (3) we construct the generalized controlled object and solve the Riccati equation, thus obtaining the controller of the HCV; (4) we simulate the controller; the simulation results show preliminarily that: (a) with measurement noise, nonlinear actuator and large-scale perturbation of model parameters, the controller tracks the rigid AOA of HCV precisely and inhibits its flexible AOA well; (b) the ± 0. 6 degree control precision of inlet local angle of attack is guaranteed, thus meeting the stringent requirements for fine attitude control of HCV.%为保证超燃冲压发动机的良好进气环境,需要对高超声速巡航飞行器进行精细姿态控制,但弹性振动大大提高了精细姿态控制的设计难度.以高超声速巡航飞行器的纵向通道为例,文章分析弹性振动对飞行控制系统的影响,建立高超声速巡航飞行器的弹性模型,将精细姿态控制问题简化为超燃冲压发动机进气口当地攻角的精细控制问题,考虑机体/发动机耦合和气动热造成了气动参数和模态参数大范围摄动问题,基于H∞理论设计鲁棒控制系统.仿真表明,在考虑测量

  5. Evaluation of robotically controlled advanced endoscopic instruments

    NARCIS (Netherlands)

    Reilink, Rob; Kappers, Astrid M.L.; Stramigioli, Stefano; Misra, Sarthak

    2013-01-01

    Background Advanced flexible endoscopes and instruments with multiple degrees of freedom enable physicians to perform challenging procedures such as the removal of large sections of mucosal tissue. However, these advanced endoscopes are difficult to control and require several physicians to cooperat

  6. Advanced Coordinating Control System for Power Plant

    Institute of Scientific and Technical Information of China (English)

    WU Peng; WEI Shuangying

    2006-01-01

    The coordinating control system is popular used in power plant. This paper describes the advanced coordinating control by control methods and optimal operation, introduces their principals and features by using the examples of power plant operation. It is wealthy for automation application in optimal power plant operation.

  7. Advanced motor-controller development

    Science.gov (United States)

    Lesster, L. E.; Zeitlin, D. B.; Hall, W. B.

    1983-06-01

    The purpose of this development program was to investigate a promising alternative technique for control of a squirrel cage induction motor for subsea propulsion or hydraulic power applications. The technique uses microprocessor based generation of the pulse width modulation waveforms, which in turn permits use of a true integral volt-second pulse width control for the generation of low harmonic content sine waves from a 3 phase Graetz transistor power bridge.

  8. Advanced thermal control for spacecraft applications

    Science.gov (United States)

    Hardesty, Robert; Parker, Kelsey

    2015-09-01

    In optical systems just like any other space borne system, thermal control plays an important role. In fact, most advanced designs are plagued with volume constraints that further complicate the thermal control challenges for even the most experienced systems engineers. Peregrine will present advances in satellite thermal control based upon passive heat transfer technologies to dissipate large thermal loads. This will address the use of 700 W/m K and higher conducting products that are five times better than aluminum on a specific basis providing enabling thermal control while maintaining structural support.

  9. The complex logic of stringent response regulation in Caulobacter crescentus: starvation signalling in an oligotrophic environment.

    Science.gov (United States)

    Boutte, Cara C; Crosson, Sean

    2011-05-01

    Bacteria rapidly adapt to nutritional changes via the stringent response, which entails starvation-induced synthesis of the small molecule, ppGpp, by RelA/SpoT homologue (Rsh) enzymes. Binding of ppGpp to RNA polymerase modulates the transcription of hundreds of genes and remodels the physiology of the cell. Studies of the stringent response have primarily focused on copiotrophic bacteria such as Escherichia coli; little is known about how stringent signalling is regulated in species that live in consistently nutrient-limited (i.e. oligotrophic) environments. Here we define the input logic and transcriptional output of the stringent response in the oligotroph, Caulobacter crescentus. The sole Rsh protein, SpoT(CC), binds to and is regulated by the ribosome, and exhibits AND-type control logic in which amino acid starvation is a necessary but insufficient signal for activation of ppGpp synthesis. While both glucose and ammonium starvation upregulate the synthesis of ppGpp, SpoT(CC) detects these starvation signals by two independent mechanisms. Although the logic of stringent response control in C. crescentus differs from E. coli, the global transcriptional effects of elevated ppGpp are similar, with the exception of 16S rRNA transcription, which is controlled independently of spoT(CC). This study highlights how the regulatory logic controlling the stringent response may be adapted to the nutritional niche of a bacterial species.

  10. Advances and applications in nonlinear control systems

    CERN Document Server

    Volos, Christos

    2016-01-01

    The book reports on the latest advances and applications of nonlinear control systems. It consists of 30 contributed chapters by subject experts who are specialized in the various topics addressed in this book. The special chapters have been brought out in the broad areas of nonlinear control systems such as robotics, nonlinear circuits, power systems, memristors, underwater vehicles, chemical processes, observer design, output regulation, backstepping control, sliding mode control, time-delayed control, variables structure control, robust adaptive control, fuzzy logic control, chaos, hyperchaos, jerk systems, hyperjerk systems, chaos control, chaos synchronization, etc. Special importance was given to chapters offering practical solutions, modeling and novel control methods for the recent research problems in nonlinear control systems. This book will serve as a reference book for graduate students and researchers with a basic knowledge of electrical and control systems engineering. The resulting design proce...

  11. Advanced nonlinear engine speed control systems

    DEFF Research Database (Denmark)

    Vesterholm, Thomas; Hendricks, Elbert

    1994-01-01

    : accurately tracking of a desired engine speed in the presence of model uncertainties and severe load disturbances. This is accomplished by using advanced nonlinear control techniques such as input/output-linearization and sliding mode control. These techniques take advantage of a nonlinear model......Several subsidiary control problems have turned out to be important for improving driveability and fuel consumption in modern spark ignition (SI) engine cars. Among these are idle speed control and cruise control. In this paper the idle speed and cruise control problems will be treated as one...

  12. Advances in chaos theory and intelligent control

    CERN Document Server

    Vaidyanathan, Sundarapandian

    2016-01-01

    The book reports on the latest advances in and applications of chaos theory and intelligent control. Written by eminent scientists and active researchers and using a clear, matter-of-fact style, it covers advanced theories, methods, and applications in a variety of research areas, and explains key concepts in modeling, analysis, and control of chaotic and hyperchaotic systems. Topics include fractional chaotic systems, chaos control, chaos synchronization, memristors, jerk circuits, chaotic systems with hidden attractors, mechanical and biological chaos, and circuit realization of chaotic systems. The book further covers fuzzy logic controllers, evolutionary algorithms, swarm intelligence, and petri nets among other topics. Not only does it provide the readers with chaos fundamentals and intelligent control-based algorithms; it also discusses key applications of chaos as well as multidisciplinary solutions developed via intelligent control. The book is a timely and comprehensive reference guide for graduate s...

  13. Advanced technologies for Mission Control Centers

    Science.gov (United States)

    Dalton, John T.; Hughes, Peter M.

    1991-01-01

    Advance technologies for Mission Control Centers are presented in the form of the viewgraphs. The following subject areas are covered: technology needs; current technology efforts at GSFC (human-machine interface development, object oriented software development, expert systems, knowledge-based software engineering environments, and high performance VLSI telemetry systems); and test beds.

  14. Advanced control architecture for autonomous vehicles

    Science.gov (United States)

    Maurer, Markus; Dickmanns, Ernst D.

    1997-06-01

    An advanced control architecture for autonomous vehicles is presented. The hierarchical architecture consists of four levels: a vehicle level, a control level, a rule-based level and a knowledge-based level. A special focus is on forms of internal representation, which have to be chosen adequately for each level. The control scheme is applied to VaMP, a Mercedes passenger car which autonomously performs missions on German freeways. VaMP perceives the environment with its sense of vision and conventional sensors. It controls its actuators for locomotion and attention focusing. Modules for perception, cognition and action are discussed.

  15. Advanced Control Techniques with Fuzzy Logic

    Science.gov (United States)

    2014-06-01

    AFRL-RQ-WP-TR-2014-0175 ADVANCED CONTROL TECHNIQUES WITH FUZZY LOGIC James E. Combs Structural Validation Branch Aerospace Vehicles...TECHNIQUES WITH FUZZY LOGIC 5a. CONTRACT NUMBER In-house 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 62201F 6. AUTHOR(S) James E. Combs...unlimited. 13. SUPPLEMENTARY NOTES PA Case Number: 88ABW-2014-3281; Clearance Date: 09 Jul 2014. 14. ABSTRACT Research on the Fuzzy Logic control

  16. MERCURY CONTROL WITH ADVANCED HYBRID PARTICULATE COLLECTOR

    Energy Technology Data Exchange (ETDEWEB)

    Ye Zhuang; Stanley J. Miller

    2005-05-01

    This project was awarded under U.S. Department of Energy (DOE) National Energy Technology Laboratory (NETL) Program Solicitation DE-PS26-00NT40769 and specifically addressed Technical Topical Area 4-Testing Novel and Less Mature Control Technologies on Actual Flue Gas at the Pilot Scale. The project team included the Energy & Environmental Research Center (EERC) as the main contractor; W.L. Gore & Associates, Inc., as a technical and financial partner; and the Big Stone Power Plant operated by Otter Tail Power Company, host for the field-testing portion of the research. Since 1995, DOE has supported development of a new concept in particulate control called the advanced hybrid particulate collector (AHPC). The AHPC has been licensed to W.L. Gore & Associates, Inc., and has been marketed as the Advanced Hybrid{trademark} filter by Gore. The Advanced Hybrid{trademark} filter combines the best features of electrostatic precipitators (ESPs) and baghouses in a unique configuration, providing major synergism between the two collection methods, both in the particulate collection step and in the transfer of dust to the hopper. The Advanced Hybrid{trademark} filter provides ultrahigh collection efficiency, overcoming the problem of excessive fine-particle emissions with conventional ESPs, and it solves the problem of reentrainment and re-collection of dust in conventional baghouses. The Advanced Hybrid{trademark} filter also appears to have unique advantages for mercury control over baghouses or ESPs as an excellent gas--solid contactor. The objective of the project was to demonstrate 90% total mercury control in the Advanced Hybrid{trademark} filter at a lower cost than current mercury control estimates. The approach included bench-scale batch tests, larger-scale pilot testing with real flue gas on a coal-fired combustion system, and field demonstration at the 2.5-MW (9000-acfm) scale at a utility power plant to prove scale-up and demonstrate longer-term mercury control

  17. Flight Hardware Packaging Design for Stringent EMC Radiated Emission Requirements

    Science.gov (United States)

    Lortz, Charlene L.; Huang, Chi-Chien N.; Ravich, Joshua A.; Steiner, Carl N.

    2013-01-01

    This packaging design approach can help heritage hardware meet a flight project's stringent EMC radiated emissions requirement. The approach requires only minor modifications to a hardware's chassis and mainly concentrates on its connector interfaces. The solution is to raise the surface area where the connector is mounted by a few millimeters using a pedestal, and then wrapping with conductive tape from the cable backshell down to the surface-mounted connector. This design approach has been applied to JPL flight project subsystems. The EMC radiated emissions requirements for flight projects can vary from benign to mission critical. If the project's EMC requirements are stringent, the best approach to meet EMC requirements would be to design an EMC control program for the project early on and implement EMC design techniques starting with the circuit board layout. This is the ideal scenario for hardware that is built from scratch. Implementation of EMC radiated emissions mitigation techniques can mature as the design progresses, with minimal impact to the design cycle. The real challenge exists for hardware that is planned to be flown following a built-to-print approach, in which heritage hardware from a past project with a different set of requirements is expected to perform satisfactorily for a new project. With acceptance of heritage, the design would already be established (circuit board layout and components have already been pre-determined), and hence any radiated emissions mitigation techniques would only be applicable at the packaging level. The key is to take a heritage design with its known radiated emissions spectrum and repackage, or modify its chassis design so that it would have a better chance of meeting the new project s radiated emissions requirements.

  18. Controlling air toxics through advanced coal preparation

    Energy Technology Data Exchange (ETDEWEB)

    Straszheim, W.E.; Buttermore, W.H.; Pollard, J.L. [Iowa State Univ., Ames, IA (United States)

    1995-11-01

    This project involves the assessment of advanced coal preparation methods for removing trace elements from coal to reduce the potential for air toxic emissions upon combustion. Scanning electron microscopy-based automated image analysis (SEM-AIA) and advanced washability analyses are being applied with state-of-the-art analytical procedures to predict the removal of elements of concern by advanced column flotation and to confirm the effectiveness of preparation on the quality of quantity of clean coal produced. Specific objectives are to maintain an acceptable recovery of combustible product, while improving the rejection of mineral-associated trace elements. Current work has focused on determining conditions for controlling column flotation system across its operating range and on selection and analysis of samples for determining trace element cleanability.

  19. Advances in neuroprosthetic learning and control.

    Directory of Open Access Journals (Sweden)

    Jose M Carmena

    Full Text Available Significant progress has occurred in the field of brain-machine interfaces (BMI since the first demonstrations with rodents, monkeys, and humans controlling different prosthetic devices directly with neural activity. This technology holds great potential to aid large numbers of people with neurological disorders. However, despite this initial enthusiasm and the plethora of available robotic technologies, existing neural interfaces cannot as yet master the control of prosthetic, paralyzed, or otherwise disabled limbs. Here I briefly discuss recent advances from our laboratory into the neural basis of BMIs that should lead to better prosthetic control and clinically viable solutions, as well as new insights into the neurobiology of action.

  20. INTEGRATED PLASMA CONTROL FOR ADVANCED TOKAMAKS

    Energy Technology Data Exchange (ETDEWEB)

    HUMPHREYS,D.A; FERRON,J.R; JOHNSON,R.D; LEUER,J.A; PENAFLOR,B.G; WALKER,M.L; WELANDER,A.S; KHAYRUTDINOV,R.R; DOKOUKA,V; EDGELL,D.H; FRANSSON,C.M

    2003-10-01

    OAK-B135 Advanced tokamaks (AT) are distinguished from conventional tokamaks by their high degree of shaping, achievement of profiles optimized for high confinement and stability characteristics, and active stabilization of MHD instabilities to attain high values of normalized beta and confinement. These high performance fusion devices thus require accurate regulation of the plasma boundary, internal profiles, pumping, fueling, and heating, as well as simultaneous and well-coordinated MHD control action to stabilize such instabilities as tearing modes and resistive wall modes. Satisfying the simultaneous demands on control accuracy, reliability, and performance for all of these subsystems requires a high degree of integration in both design and operation of the plasma control system in an advanced tokamak. The present work describes the approach, benefits, and progress made in integrated plasma control with application examples drawn from the DIII-D tokamak. The approach includes construction of plasma and system response models, validation of models against operating experiments, design of integrated controllers which operate in concert with one another as well as with supervisory modules, simulation of control action against off-line and actual machine control platforms, and iteration of the design-test loop to optimize performance.

  1. Industrial applications of advanced control techniques

    Institute of Scientific and Technical Information of China (English)

    刘国平

    2003-01-01

    This paper discusses two industrial control applications using advanced control techniques. They are theoptimal-tuning nonlinear PID control of hydraulic systems and the neural predictive control of combustor acoustic ofgas turbines. For hydraulic control systems, an optimal PID controller with inverse of dead zone is introduced toovercome the dead zone and is designed to satisfy desired time-domain performance requirements. Using the adaptivemodel, an optimal-tuning PID control scheme is proposed to provide optimal PID parameters even in the case wherethe system dynamics is time variant. For combustor acoustic control of gas turbines, a neural predictive controlstrategy is presented, which consists of three parts: an output model, output predictor and feedback controller. Theoutput model of the combustor acoustic is established using neural networks to predict the output and overcome thetime delay of the system, which is often very large, compared with the sampling period. The output-feedback con-troller is introduced which uses the output of the predictor to suppress instability in the combustion process. The a-bove control strategies are implemented in the SIMULINK/dSPACE controller development environment. Theirperformance is evaluated on the industrial hydraulic test rig and the industrial combustor test rig.

  2. Recent Advances in Iterative Learning Control

    Institute of Scientific and Technical Information of China (English)

    Jian-Xin XU

    2005-01-01

    In this paper we review the recent advances in three sub-areas of iterative learning control (ILC): 1) linear ILC for linear processes, 2) linear ILC for nonlinear processes which are global Lipschitz continuous (GLC), and 3) nonlinear ILC for general nonlinear processes. For linear processes, we focus on several basic configurations of linear ILC. For nonlinear processes with linear ILC, we concentrate on the design and transient analysis which were overlooked and missing for a long period. For general classes of nonlinear processes, we demonstrate nonlinear ILC methods based on Lyapunov theory, which is evolving into a new control paradigm.

  3. An autonomous control framework for advanced reactors

    Directory of Open Access Journals (Sweden)

    Richard T. Wood

    2017-08-01

    Full Text Available Several Generation IV nuclear reactor concepts have goals for optimizing investment recovery through phased introduction of multiple units on a common site with shared facilities and/or reconfigurable energy conversion systems. Additionally, small modular reactors are suitable for remote deployment to support highly localized microgrids in isolated, underdeveloped regions. The long-term economic viability of these advanced reactor plants depends on significant reductions in plant operations and maintenance costs. To accomplish these goals, intelligent control and diagnostic capabilities are needed to provide nearly autonomous operations with anticipatory maintenance. A nearly autonomous control system should enable automatic operation of a nuclear power plant while adapting to equipment faults and other upsets. It needs to have many intelligent capabilities, such as diagnosis, simulation, analysis, planning, reconfigurability, self-validation, and decision. These capabilities have been the subject of research for many years, but an autonomous control system for nuclear power generation remains as-yet an unrealized goal. This article describes a functional framework for intelligent, autonomous control that can facilitate the integration of control, diagnostic, and decision-making capabilities to satisfy the operational and performance goals of power plants based on multimodular advanced reactors.

  4. Rapid Curtailing of the Stringent Response by Toxin-Antitoxin Encoded mRNases

    DEFF Research Database (Denmark)

    Tian, Chengzhe; Roghanian, Mohammad; Jørgensen, Mikkel Girke

    2016-01-01

    Escherichia coli regulates its metabolism to adapt to changes in the environment, in particular to stressful downshifts in nutrient quality. Such shifts elicit the so-called stringent response coordinated by the alarmone guanosine tetra- and pentaphosphate [(p)ppGpp]. At sudden amino-acid (aa...... %. IMPORTANCE: The early stringent response elicited by amino-acid starvation is controlled by a sharp increase of the cellular (p)ppGpp level. Toxin-antitoxin encoded mRNases are activated by (p)ppGpp through enhanced degradation of antitoxins. The present work shows that this activation happens at a very...

  5. ADVANCED PROCESS CONTROL DEVELOPMENT IN RESIDUA CATALYTIC CRACKER CONTROL

    Institute of Scientific and Technical Information of China (English)

    2000-01-01

    Process calculations and rigorous dynamic model with detailed coke combustion kine-tics for two-stage regeneration FCC process were developed and integrated into the advanced process control(APC) context. The package was implemented in 6 SINOPEC commercial RFCCUs.Typical 0.5%~0.8% improvement of target product yields was achieved. Significant energy consumption was saved with tighter control over coke burning.

  6. JPL Advanced Thermal Control Technology Roadmap - 2008

    Science.gov (United States)

    Birur, Gaj

    2008-01-01

    This slide presentation reviews the status of thermal control technology at JPL and NASA.It shows the active spacecraft that are in vairous positions in the solar syatem, and beyond the solar system and the future missions that are under development. It then describes the challenges that the past missions posed with the thermal control systems. The various solutions that were implemented duirng the decades prior to 1990 are outlined. A review of hte thermal challenges of the future misions is also included. The exploration plan for Mars is then reviewed. The thermal challenges of the Mars Rovers are then outlined. Also the challenges of systems that would be able to be used in to explore Venus, and Titan are described. The future space telescope missions will also need thermal control technological advances. Included is a review of the thermal requirements for manned missions to the Moon. Both Active and passive technologies that have been used and will be used are reviewed. Those that are described are Mechanically Pumped Fluid Loops (MPFL), Loop Heat Pipes, an M3 Passive Cooler, Heat Siwtch for Space and Mars surface applications, phase change material (PCM) technology, a Gas Gap Actuateor using ZrNiH(x), the Planck Sorption Cooler (PCS), vapor compression -- Hybrid two phase loops, advanced pumps for two phase cooling loops, and heat pumps that are lightweight and energy efficient.

  7. Advances in dynamical systems and control

    CERN Document Server

    Zgurovsky, Mikhail

    2016-01-01

    Focused on recent advances, this book covers theoretical foundations as well as various applications. It presents modern mathematical modeling approaches to the qualitative and numerical analysis of solutions for complex engineering problems in physics, mechanics, biochemistry, geophysics, biology and climatology. Contributions by an international team of respected authors bridge the gap between abstract mathematical approaches, such as applied methods of modern analysis, algebra, fundamental and computational mechanics, nonautonomous and stochastic dynamical systems on the one hand, and practical applications in nonlinear mechanics, optimization, decision making theory and control theory on the other. As such, the book will be of interest to mathematicians and engineers working at the interface of these fields. .

  8. Prototyping Advanced Control Systems on FPGA

    Directory of Open Access Journals (Sweden)

    Simard Stéphane

    2009-01-01

    Full Text Available In advanced digital control and mechatronics, FPGA-based systems on a chip (SoCs promise to supplant older technologies, such as microcontrollers and DSPs. However, the tackling of FPGA technology by control specialists is complicated by the need for skilled hardware/software partitioning and design in order to match the performance requirements of more and more complex algorithms while minimizing cost. Currently, without adequate software support to provide a straightforward design flow, the amount of time and efforts required is prohibitive. In this paper, we discuss our choice, adaptation, and use of a rapid prototyping platform and design flow suitable for the design of on-chip motion controllers and other SoCs with a need for analog interfacing. The platform consists of a customized FPGA design for the Amirix AP1000 PCI FPGA board coupled with a multichannel analog I/O daughter card. The design flow uses Xilinx System Generator in Matlab/Simulink for system design and test, and Xilinx Platform Studio for SoC integration. This approach has been applied to the analysis, design, and hardware implementation of a vector controller for 3-phase AC induction motors. It also has contributed to the development of CMC's MEMS prototyping platform, now used by several Canadian laboratories.

  9. The stringent response and cell cycle arrest in Escherichia coli.

    Directory of Open Access Journals (Sweden)

    Daniel J Ferullo

    2008-12-01

    Full Text Available The bacterial stringent response, triggered by nutritional deprivation, causes an accumulation of the signaling nucleotides pppGpp and ppGpp. We characterize the replication arrest that occurs during the stringent response in Escherichia coli. Wild type cells undergo a RelA-dependent arrest after treatment with serine hydroxamate to contain an integer number of chromosomes and a replication origin-to-terminus ratio of 1. The growth rate prior to starvation determines the number of chromosomes upon arrest. Nucleoids of these cells are decondensed; in the absence of the ability to synthesize ppGpp, nucleoids become highly condensed, similar to that seen after treatment with the translational inhibitor chloramphenicol. After induction of the stringent response, while regions corresponding to the origins of replication segregate, the termini remain colocalized in wild-type cells. In contrast, cells arrested by rifampicin and cephalexin do not show colocalized termini, suggesting that the stringent response arrests chromosome segregation at a specific point. Release from starvation causes rapid nucleoid reorganization, chromosome segregation, and resumption of replication. Arrest of replication and inhibition of colony formation by ppGpp accumulation is relieved in seqA and dam mutants, although other aspects of the stringent response appear to be intact. We propose that DNA methylation and SeqA binding to non-origin loci is necessary to enforce a full stringent arrest, affecting both initiation of replication and chromosome segregation. This is the first indication that bacterial chromosome segregation, whose mechanism is not understood, is a step that may be regulated in response to environmental conditions.

  10. The Advanced Controls Program at Oak Ridge National Laboratory

    Energy Technology Data Exchange (ETDEWEB)

    Knee, H.E.; White, J.D.

    1990-01-01

    The Oak Ridge National Laboratory (ORNL), under sponsorship of the US Department of Energy (DOE), is conducting research that will lead to advanced, automated control of new liquid-metal-reactor (LMR) nuclear power plants. Although this program of research (entitled the Advanced Controls Program'') is focused on LMR technology, it will be capable of providing control design, test, and qualification capability for other advanced reactor designs (e.g., the advanced light water reactor (ALWR) and high temperature gas-cooled reactor (HTGR) designs), while also benefiting existing nuclear plants. The Program will also have applicability to complex, non-nuclear process control environments (e.g., petrochemical, aerospace, etc.). The Advanced Controls Program will support capabilities throughout the entire plant design life cycle, i.e., from the initial interactive first-principle dynamic model development for the process, systems, components, and instruments through advanced control room qualification. The current program involves five principal areas of research activities: (1) demonstrations of advanced control system designs, (2) development of an advanced controls design environment, (3) development of advanced control strategies, (4) research and development (R D) in human-system integration for advanced control system designs, and (5) testing and validation of advanced control system designs. Discussion of the research in these five areas forms the basis of this paper. Also included is a description of the research directions of the program. 8 refs.

  11. Advanced Emissions Control Development Program: Phase III

    Energy Technology Data Exchange (ETDEWEB)

    G.T. Amrhein; R.T. Bailey; W. Downs; M.J. Holmes; G.A. Kudlac; D.A. Madden

    1999-07-01

    The primary objective of the Advanced Emissions Control Development Program (AECDP) is to develop practical, cost-effective strategies for reducing the emissions of air toxics from coal-fired boilers. The project goal is to effectively control air toxic emissions through the use of conventional flue gas clean-up equipment such as electrostatic precipitators (ESPs), fabric filters (baghouses - BH), and wet flue gas desulfurization systems (WFGD). Development work concentrated on the capture of trace metals, fine particulate, hydrogen chloride and hydrogen fluoride, with an emphasis on the control of mercury. The AECDP project is jointly funded by the US Department of Energy's Federal Energy Technology Center (DOE), the Ohio Coal Development Office within the Ohio Department of Development (OCDO), and Babcock and Wilcox, a McDermott company (B and W). This report discusses results of all three phases of the AECDP project with an emphasis on Phase III activities. Following the construction and evaluation of a representative air toxics test facility in Phase I, Phase II focused on characterization of the emissions of mercury and other air toxics and the control of these emissions for typical operating conditions of conventional flue gas clean-up equipment. Some general comments that can be made about the control of air toxics while burning a high-sulfur bituminous coal are as follows: (1) particulate control devices such as ESP's and baghouses do a good job of removing non-volatile trace metals, (2) particulate control devices (ESPs and baghouses) effectively remove the particulate-phase mercury, but the particulate-phase mercury was only a small fraction of the total for the coals tested, (3) wet scrubbing can effectively remove hydrogen chloride and hydrogen fluoride, and (4) wet scrubbers show good potential for the removal of mercury when operated under certain conditions, however, for certain applications, system enhancements can be required to achieve

  12. The stringent response in Streptomyces coelicolor A3(2)

    NARCIS (Netherlands)

    Strauch, E.; Takano, E.; Baylis, H.A.; Bibb, M.J.

    1991-01-01

    The stringent response was elicited in the antibiotic producer Streptomyces coelicolor A3(2) either by amino acid depletion (nutritional shiftdown) or by the addition of serine hydroxamate; both led to increased levels of ppGpp and to a reduction in transcription from the four promoters of the rrnD

  13. Circuitry linking the Csr and stringent response global regulatory systems.

    Science.gov (United States)

    Edwards, Adrianne N; Patterson-Fortin, Laura M; Vakulskas, Christopher A; Mercante, Jeffrey W; Potrykus, Katarzyna; Vinella, Daniel; Camacho, Martha I; Fields, Joshua A; Thompson, Stuart A; Georgellis, Dimitris; Cashel, Michael; Babitzke, Paul; Romeo, Tony

    2011-06-01

    CsrA protein regulates important cellular processes by binding to target mRNAs and altering their translation and/or stability. In Escherichia coli, CsrA binds to sRNAs, CsrB and CsrC, which sequester CsrA and antagonize its activity. Here, mRNAs for relA, spoT and dksA of the stringent response system were found among 721 different transcripts that copurified with CsrA. Many of the transcripts that copurified with CsrA were previously determined to respond to ppGpp and/or DksA. We examined multiple regulatory interactions between the Csr and stringent response systems. Most importantly, DksA and ppGpp robustly activated csrB/C transcription (10-fold), while they modestly activated csrA expression. We propose that CsrA-mediated regulation is relieved during the stringent response. Gel shift assays confirmed high affinity binding of CsrA to relA mRNA leader and weaker interactions with dksA and spoT. Reporter fusions, qRT-PCR and immunoblotting showed that CsrA repressed relA expression, and (p)ppGpp accumulation during stringent response was enhanced in a csrA mutant. CsrA had modest to negligible effects on dksA and spoT expression. Transcription of dksA was negatively autoregulated via a feedback loop that tended to mask CsrA effects. We propose that the Csr system fine-tunes the stringent response and discuss biological implications of the composite circuitry.

  14. Ervaringen met Advanced Cruise Control (ACC) in een korte praktijkproef.

    NARCIS (Netherlands)

    Oei, H.-l.

    2003-01-01

    Experiences with Advanced Cruise Control in traffic; a limited experiment. Advanced Cruise Control (ACC) is an ordinary cruise control in which the desired speed is installed manually, but in which the headway time to the vehicle in front is also taken into account. If the headway time becomes less

  15. Advanced and controlled drug delivery systems in clinical disease management

    NARCIS (Netherlands)

    Brouwers, JRBJ

    1996-01-01

    Advanced and controlled drug delivery systems are important for clinical disease management. In this review the most important new systems which have reached clinical application are highlighted. Microbiologically controlled drug delivery is important for gastrointestinal diseases like ulcerative co

  16. Advanced control of a water supply system: a case study

    NARCIS (Netherlands)

    Bakker, M.; Rajewicz, T.; Kien, H.; Vreeburg, J.H.G.; Rietveld, L.C.

    2014-01-01

    Conventional automatic production flow control and pump pressure control of water supply systems are robust and simple: production flow is controlled based on the level in the clear water reservoir and pump pressure is controlled on a static set-point. Recently, more advanced computer-based control

  17. Generic Model Predictive Control Framework for Advanced Driver Assistance Systems

    NARCIS (Netherlands)

    Wang, M.

    2014-01-01

    This thesis deals with a model predictive control framework for control design of Advanced Driver Assistance Systems, where car-following tasks are under control. The framework is applied to design several autonomous and cooperative controllers and to examine the controller properties at the microsc

  18. Generic Model Predictive Control Framework for Advanced Driver Assistance Systems

    NARCIS (Netherlands)

    Wang, M.

    2014-01-01

    This thesis deals with a model predictive control framework for control design of Advanced Driver Assistance Systems, where car-following tasks are under control. The framework is applied to design several autonomous and cooperative controllers and to examine the controller properties at the microsc

  19. Advanced Control Law Tuning and Performance Assessment

    Science.gov (United States)

    2006-12-01

    range. The Fig. 21 shows the response of the NGMV controller and of two of the PID controllers obtained. The dynamic response of the NGMV controller...is very close to the original one, despite the significant increase in the time delay. It was not possible to obtain, for the PID controllers , both

  20. Overview of advanced process control in welding within ERDA

    Energy Technology Data Exchange (ETDEWEB)

    Armstrong, R.E.

    1977-02-11

    The special kinds of demands placed on ERDA weapons and reactors require them to have very reliable welds. Process control is critical in achieving this reliability. ERDA has a number of advanced process control projects underway with much of the emphasis being on electron beam welding. These include projects on voltage measurement, beam-current control, beam focusing, beam spot tracking, spike suppression, and computer control. A general discussion of process control in welding is followed by specific examples of some of the advanced joining process control projects in ERDA.

  1. Recent Technology Advances in Distributed Engine Control

    Science.gov (United States)

    Culley, Dennis

    2017-01-01

    This presentation provides an overview of the work performed at NASA Glenn Research Center in distributed engine control technology. This is control system hardware technology that overcomes engine system constraints by modularizing control hardware and integrating the components over communication networks.

  2. Advanced Stellar Compass, SAC-C, Interface Control Document

    DEFF Research Database (Denmark)

    Madsen, Peter Buch; Betto, Maurizio; Riis, Troels;

    Interface Control Document for the Advanced Stellar Compass for the SAC-C satellite. The SAC-C is Argentine, Danish and NASA satellite. On the SAC-C satellite there are a simplified version of the Ørsted instrumentation platform. The Advanced Stellar Compass is a improved version of the Ørsted Star...... Imager. This document descibes the interface between the Advanced Stellar Compass and OBDH, the size of the DPU and the Camera etc....

  3. Comparison of advanced distillation control methods. First annual report

    Energy Technology Data Exchange (ETDEWEB)

    Riggs, J.B.

    1996-11-01

    A detailed dynamic simulator of a propylene/propane (C{sub 3}) splitter, which was bench-marked against industrial data, has been used to compare dual composition control performance for a diagonal PI controller and several advanced controllers. The advanced controllers considered are dynamic matrix control (DMC), nonlinear process model based control, and artificial neutral networks. Each controller was tuned based upon setpoint changes in the overhead product composition using 50% changes in the impurity levels. Overall, there was not a great deal of difference in controller performance based upon the setpoint and disturbance tests. Periodic step changes in feed composition were also used to compare controller performance. In this case, oscillatory variations of the product composition were observed and the variabilities of the DC and nonlinear process model based controllers were substantially smaller than that of the PI controller. The sensitivity of each controller to the frequency of the periodic step changes in feed composition was also investigated.

  4. Mechanics and model-based control of advanced engineering systems

    CERN Document Server

    Irschik, Hans; Krommer, Michael

    2014-01-01

    Mechanics and Model-Based Control of Advanced Engineering Systems collects 32 contributions presented at the International Workshop on Advanced Dynamics and Model Based Control of Structures and Machines, which took place in St. Petersburg, Russia in July 2012. The workshop continued a series of international workshops, which started with a Japan-Austria Joint Workshop on Mechanics and Model Based Control of Smart Materials and Structures and a Russia-Austria Joint Workshop on Advanced Dynamics and Model Based Control of Structures and Machines. In the present volume, 10 full-length papers based on presentations from Russia, 9 from Austria, 8 from Japan, 3 from Italy, one from Germany and one from Taiwan are included, which represent the state of the art in the field of mechanics and model based control, with particular emphasis on the application of advanced structures and machines.

  5. Advanced Combustion and Emission Control Technical Team Roadmap

    Energy Technology Data Exchange (ETDEWEB)

    None

    2013-06-01

    The Advanced Combustion and Emission Control (ACEC) Technical Team is focused on removing technical barriers to the commercialization of advanced, high-efficiency, emission-compliant internal combustion (IC) engines for light-duty vehicle powertrains (i.e., passenger car, minivan, SUV, and pickup trucks).

  6. Model-free adaptive control of advanced power plants

    Energy Technology Data Exchange (ETDEWEB)

    Cheng, George Shu-Xing; Mulkey, Steven L.; Wang, Qiang

    2015-08-18

    A novel 3-Input-3-Output (3.times.3) Model-Free Adaptive (MFA) controller with a set of artificial neural networks as part of the controller is introduced. A 3.times.3 MFA control system using the inventive 3.times.3 MFA controller is described to control key process variables including Power, Steam Throttle Pressure, and Steam Temperature of boiler-turbine-generator (BTG) units in conventional and advanced power plants. Those advanced power plants may comprise Once-Through Supercritical (OTSC) Boilers, Circulating Fluidized-Bed (CFB) Boilers, and Once-Through Supercritical Circulating Fluidized-Bed (OTSC CFB) Boilers.

  7. Model-free adaptive control of advanced power plants

    Science.gov (United States)

    Cheng, George Shu-Xing; Mulkey, Steven L.; Wang, Qiang

    2015-08-18

    A novel 3-Input-3-Output (3.times.3) Model-Free Adaptive (MFA) controller with a set of artificial neural networks as part of the controller is introduced. A 3.times.3 MFA control system using the inventive 3.times.3 MFA controller is described to control key process variables including Power, Steam Throttle Pressure, and Steam Temperature of boiler-turbine-generator (BTG) units in conventional and advanced power plants. Those advanced power plants may comprise Once-Through Supercritical (OTSC) Boilers, Circulating Fluidized-Bed (CFB) Boilers, and Once-Through Supercritical Circulating Fluidized-Bed (OTSC CFB) Boilers.

  8. ADVANCED CONTROL OF A COMPLEX CHEMICAL PROCESS

    Directory of Open Access Journals (Sweden)

    Roxana Both

    Full Text Available Abstract Three phase catalytic hydrogenation reactors are important reactors with complex behavior due to the interaction among gas, solid and liquid phases with the kinetic, mass and heat transfer mechanisms. A nonlinear distributed parameter model was developed based on mass and energy conservation principles. It consists of balance equations for the gas and liquid phases, so that a system of partial differential equations is generated. Because detailed nonlinear mathematical models are not suitable for use in controller design, a simple linear mathematical model of the process, which describes its most important properties, was determined. Both developed mathematical models were validated using plant data. The control strategies proposed in this paper are a multivariable Smith Predictor PID controller and multivariable Smith Predictor structure in which the primary controllers are derived based on Internal Model Control. Set-point tracking and disturbance rejection tests are presented for both methods based on scenarios implemented in Matlab/SIMULINK.

  9. ADVANCED CONTROL FOR A ETHYLENE REACTOR

    Directory of Open Access Journals (Sweden)

    Dumitru POPESCU

    2017-06-01

    Full Text Available The main objective of this work is the design and implementation of control solutions for petrochemical processes, namely the control and optimization of a pyrolysis reactor, the key-installation in the petrochemical industry. We present the technological characteristics of this petrochemical process and some aspects about the proposed control system solution for the ethylene plant. Finally, an optimal operating point for the reactor is found, considering that the process has a nonlinear multi-variable structure. The results have been implemented on an assembly of pyrolysis reactors on a petrochemical platform from Romania.

  10. Safety Cases for Advanced Control Software: Safety Case Patterns

    Science.gov (United States)

    2007-10-15

    Classification Argument (from [14]) The classification of software failure modes can be useful for adaptive systems. Kurd in [15] shows how HAZOPS ...Safety Cases for Advanced Control Software : Safety Case Patterns Robert Alexander, Tim Kelly, Zeshan Kurd, John...5a. CONTRACT NUMBER FA8655-07-1-3025 5b. GRANT NUMBER 4. TITLE AND SUBTITLE Safety Cases for Advanced Control Software 5c. PROGRAM ELEMENT

  11. Azimuthal anisotropies as stringent test for nuclear transport models

    Science.gov (United States)

    Crochet, P.; Rami, F.; Donà, R.; Coffin, J. P.; Fintz, P.; Guillaume, G.; Jundt, F.; Kuhn, C.; Roy, C.; de Schauenburg, B.; Tizniti, L.; Wagner, P.; Alard, J. P.; Andronic, A.; Basrak, Z.; Bastid, N.; Belyaev, I.; Bendarag, A.; Berek, G.; Best, D.; Biegansky, J.; Buta, A.; Čaplar, R.; Cindro, N.; Dupieux, P.; Dželalija, M.; Fan, Z. G.; Fodor, Z.; Fraysse, L.; Freifelder, R. P.; Gobbi, A.; Herrmann, N.; Hildenbrand, K. D.; Hong, B.; Jeong, S. C.; Kecskemeti, J.; Kirejczyk, M.; Koncz, P.; Korolija, M.; Kotte, R.; Lebedev, A.; Leifels, Y.; Manko, V.; Moisa, D.; Mösner, J.; Neubert, W.; Pelte, D.; Petrovici, M.; Pinkenburg, C.; Reisdorf, W.; Ritman, J. L.; Sadchikov, A. G.; Schüll, D.; Seres, Z.; Sikora, B.; Simion, V.; Siwek-Wilczyńska, K.; Sodan, U.; Teh, K. M.; Trzaska, M.; Wang, G. S.; Wessels, J. P.; Wienold, T.; Wisniewski, K.; Wohlfarth, D.; Zhilin, A.; Hartnack, C.; FOPI Collaboration

    1997-02-01

    Azimuthal distributions of charged particles and intermediate mass fragments emitted in Au+Au collisions at 600 A MeV have been measured using the FOPI facility at GSI-Darmstadt. Data show a strong increase of the in-plane azimuthal anisotropy ratio with the charge of the detected fragment. Intermediate mass fragments are found to exhibit a strong momentum-space alignment with respect of the reaction plane. The experimental results are presented as a function of the polar centre-of-mass angle and over a broad range of impact parameters. They are compared to the predictions of the Isospin Quantum Molecular Dynamics model using three different parametrisations of the equation of state. We show that such highly accurate data provide stringent test for microscopic transport models and can potentially constrain separately the stiffness of the nuclear equation of state and the momentum dependence of the nuclear interaction.

  12. Relacin, a novel antibacterial agent targeting the Stringent Response.

    Directory of Open Access Journals (Sweden)

    Ezequiel Wexselblatt

    2012-09-01

    Full Text Available Finding bacterial cellular targets for developing novel antibiotics has become a major challenge in fighting resistant pathogenic bacteria. We present a novel compound, Relacin, designed to inhibit (pppGpp production by the ubiquitous bacterial enzyme RelA that triggers the Stringent Response. Relacin inhibits RelA in vitro and reduces (pppGpp production in vivo. Moreover, Relacin affects entry into stationary phase in Gram positive bacteria, leading to a dramatic reduction in cell viability. When Relacin is added to sporulating Bacillus subtilis cells, it strongly perturbs spore formation regardless of the time of addition. Spore formation is also impeded in the pathogenic bacterium Bacillus anthracis that causes the acute anthrax disease. Finally, the formation of multicellular biofilms is markedly disrupted by Relacin. Thus, we establish that Relacin, a novel ppGpp analogue, interferes with bacterial long term survival strategies, placing it as an attractive new antibacterial agent.

  13. Attitude Control Subsystem for the Advanced Communications Technology Satellite

    Science.gov (United States)

    Hewston, Alan W.; Mitchell, Kent A.; Sawicki, Jerzy T.

    1996-01-01

    This paper provides an overview of the on-orbit operation of the Attitude Control Subsystem (ACS) for the Advanced Communications Technology Satellite (ACTS). The three ACTS control axes are defined, including the means for sensing attitude and determining the pointing errors. The desired pointing requirements for various modes of control as well as the disturbance torques that oppose the control are identified. Finally, the hardware actuators and control loops utilized to reduce the attitude error are described.

  14. Cooperative research for human factors review of advanced control rooms

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Jung Woon; Park, Jae Chang; Lee, Yong Hee; Oh, In Seok; Lee, Hyun Chul

    2000-12-01

    This project has been performed as cooperative research between KAERI and USNRC. Human factors issues related to soft controls, which is one of key features of advanced HSI, are identified in this project. The issues are analyzed for the evaluation approaches in either experimental or analytical ways. Also, issues requiring additional researches for the evaluation of advanced HSI are identified in the areas of advanced information systems design, computer-based procedure systems, soft controls, human systems interface and plant modernization process, and maintainability of digital systems. The issues are analyzed to discriminate the urgency of researches on it to high, medium, and low levels in consideration of advanced HSI development status in Korea, and some of the issues that can be handled by experimental researches are identified. Additionally, an experimental study is performed to compare operator's performance on human error detection in advanced control rooms vs. in conventional control rooms. It is found that advanced control rooms have several design characteristics hindering operator's error detection performance compared to conventional control rooms.

  15. Automated Deployment of Advanced Controls and Analytics in Buildings

    Science.gov (United States)

    Pritoni, Marco

    Buildings use 40% of primary energy in the US. Recent studies show that developing energy analytics and enhancing control strategies can significantly improve their energy performance. However, the deployment of advanced control software applications has been mostly limited to academic studies. Larger-scale implementations are prevented by the significant engineering time and customization required, due to significant differences among buildings. This study demonstrates how physics-inspired data-driven models can be used to develop portable analytics and control applications for buildings. Specifically, I demonstrate application of these models in all phases of the deployment of advanced controls and analytics in buildings: in the first phase, "Site Preparation and Interface with Legacy Systems" I used models to discover or map relationships among building components, automatically gathering metadata (information about data points) necessary to run the applications. During the second phase: "Application Deployment and Commissioning", models automatically learn system parameters, used for advanced controls and analytics. In the third phase: "Continuous Monitoring and Verification" I utilized models to automatically measure the energy performance of a building that has implemented advanced control strategies. In the conclusions, I discuss future challenges and suggest potential strategies for these innovative control systems to be widely deployed in the market. This dissertation provides useful new tools in terms of procedures, algorithms, and models to facilitate the automation of deployment of advanced controls and analytics and accelerate their wide adoption in buildings.

  16. Control of Smart Building Using Advanced SCADA

    Science.gov (United States)

    Samuel, Vivin Thomas

    For complete control of the building, a proper SCADA implementation and the optimization strategy has to be build. For better communication and efficiency a proper channel between the Communication protocol and SCADA has to be designed. This paper concentrate mainly between the communication protocol, and the SCADA implementation, for a better optimization and energy savings is derived to large scale industrial buildings. The communication channel used in order to completely control the building remotely from a distant place. For an efficient result we consider the temperature values and the power ratings of the equipment so that while controlling the equipment, we are setting a threshold values for FDD technique implementation. Building management system became a vital source for any building to maintain it and for safety purpose. Smart buildings, refers to various distinct features, where the complete automation system, office building controls, data center controls. ELC's are used to communicate the load values of the building to the remote server from a far location with the help of an Ethernet communication channel. Based on the demand fluctuation and the peak voltage, the loads operate differently increasing the consumption rate thus results in the increase in the annual consumption bill. In modern days, saving energy and reducing the consumption bill is most essential for any building for a better and long operation. The equipment - monitored regularly and optimization strategy is implemented for cost reduction automation system. Thus results in the reduction of annual cost reduction and load lifetime increase.

  17. Advanced mobile networking, sensing, and controls.

    Energy Technology Data Exchange (ETDEWEB)

    Feddema, John Todd; Kilman, Dominique Marie; Byrne, Raymond Harry; Young, Joseph G.; Lewis, Christopher L.; Van Leeuwen, Brian P.; Robinett, Rush D. III; Harrington, John J.

    2005-03-01

    This report describes an integrated approach for designing communication, sensing, and control systems for mobile distributed systems. Graph theoretic methods are used to analyze the input/output reachability and structural controllability and observability of a decentralized system. Embedded in each network node, this analysis will automatically reconfigure an ad hoc communication network for the sensing and control task at hand. The graph analysis can also be used to create the optimal communication flow control based upon the spatial distribution of the network nodes. Edge coloring algorithms tell us that the minimum number of time slots in a planar network is equal to either the maximum number of adjacent nodes (or degree) of the undirected graph plus some small number. Therefore, the more spread out that the nodes are, the fewer number of time slots are needed for communication, and the smaller the latency between nodes. In a coupled system, this results in a more responsive sensor network and control system. Network protocols are developed to propagate this information, and distributed algorithms are developed to automatically adjust the number of time slots available for communication. These protocols and algorithms must be extremely efficient and only updated as network nodes move. In addition, queuing theory is used to analyze the delay characteristics of Carrier Sense Multiple Access (CSMA) networks. This report documents the analysis, simulation, and implementation of these algorithms performed under this Laboratory Directed Research and Development (LDRD) effort.

  18. Human factors survey of advanced instrumentation and controls

    Energy Technology Data Exchange (ETDEWEB)

    Carter, R.J.

    1989-01-01

    A survey oriented towards identifying the human factors issues in regard to the use of advanced instrumentation and controls (I C) in the nuclear industry was conducted. A number of United States (US) and Canadian nuclear vendors and utilities were participants in the survey. Human factors items, subsumed under the categories of computer-generated displays (CGD), controls, organizational support, training, and related topics, were discussed. The survey found the industry to be concerned about the human factors issues related to the implementation of advanced I C. Fifteen potential human factors problems were identified. They include: the need for an advanced I C guideline equivalent to NUREG-0700; a role change in the control room from operator to supervisor; information overload; adequacy of existing training technology for advanced I C; and operator acceptance and trust. 11 refs., 1 tab.

  19. Advanced Control Techniques for WEC Wave Dragon

    DEFF Research Database (Denmark)

    Tedd, James; Kofoed, Jens Peter; Jasinski, M.;

    2007-01-01

    This paper presents the ongoing work on control of the Wave Dragon wave energy converter. Research is being conducted in and between several centers across Europe. This is building upon the knowledge gained in the prototype project, and will enable much better performance of the future deployment...

  20. Advanced Attitude Control af Pico Sized Satellites

    DEFF Research Database (Denmark)

    Larsen, Jesper A.; Amini, Rouzbeh; Izadi-Zamanabadi, Roozbeh

    2005-01-01

    accuracy of better than 5 degrees. Cost, size, weight and power requirements, on the other hand, impose selecting relative simple sensors and actuators which leads to an attitude control requirement of less than 1 degree. This precision is obtained by a combination of magnetorquers and momentum wheels...

  1. Advanced Stellar Compass, CHAMP, Interface Control Document

    DEFF Research Database (Denmark)

    Madsen, Peter Buch; Jørgensen, John Leif; Betto, Maurizio;

    1999-01-01

    The German government research establishment "GeoForschungsZentrum" developed under a contract to the German government a microsatellite named "Champ". The Space Instrumentation Group has made a Interface Control Document for the CHAMP, witch describes the Star Imager, the electrical interface, t...

  2. Optimal Inventory Control with Advance Supply Information

    Directory of Open Access Journals (Sweden)

    Marko Jaksic

    2016-09-01

    Full Text Available It has been shown in numerous situations that sharing information between the companies leads to improved performance of the supply chain. We study a positive lead time periodic-review inventory system of a retailer facing stochastic demand from his customer and stochastic limited supply capacity of the manufacturer supplying the products to him. The consequence of stochastic supply capacity is that the orders might not be delivered in full, and the exact size of the replenishment might not be known to the retailer. The manufacturer is willing to share the so-called advance supply information (ASI about the actual replenishment of the retailer's pipeline order with the retailer. ASI is provided at a certain time after the orders have been placed and the retailer can now use this information to decrease the uncertainty of the supply, and thus improve its inventory policy. For this model, we develop a dynamic programming formulation, and characterize the optimal ordering policy as a state-dependent base-stock policy. In addition, we show some properties of the base-stock level. While the optimal policy is highly complex, we obtain some additional insights by comparing it to the state-dependent myopic inventory policy. We conduct the numerical analysis to estimate the in uence of the system parameters on the value of ASI. While we show that the interaction between the parameters is relatively complex, the general insight is that due to increasing marginal returns, the majority of the benets are gained only in the case of full, or close to full, ASI visibility.

  3. Advances in Computer, Communication, Control and Automation

    CERN Document Server

    011 International Conference on Computer, Communication, Control and Automation

    2012-01-01

    The volume includes a set of selected papers extended and revised from the 2011 International Conference on Computer, Communication, Control and Automation (3CA 2011). 2011 International Conference on Computer, Communication, Control and Automation (3CA 2011) has been held in Zhuhai, China, November 19-20, 2011. This volume  topics covered include signal and Image processing, speech and audio Processing, video processing and analysis, artificial intelligence, computing and intelligent systems, machine learning, sensor and neural networks, knowledge discovery and data mining, fuzzy mathematics and Applications, knowledge-based systems, hybrid systems modeling and design, risk analysis and management, system modeling and simulation. We hope that researchers, graduate students and other interested readers benefit scientifically from the proceedings and also find it stimulating in the process.

  4. Advanced CIDI Emission Control System Development

    Energy Technology Data Exchange (ETDEWEB)

    Lambert, Christine

    2006-05-31

    Ford Motor Company, with ExxonMobil and FEV, participated in the Department of Energy's (DOE) Ultra-Clean Transportation Fuels Program with the goal to develop an innovative emission control system for light-duty diesel vehicles. The focus on diesel engine emissions was a direct result of the improved volumetric fuel economy (up to 50%) and lower CO2 emissions (up to 25%) over comparable gasoline engines shown in Europe. Selective Catalytic Reduction (SCR) with aqueous urea as the NOx reductant and a Catalyzed Diesel Particulate Filter (CDPF) were chosen as the primary emission control system components. The program expected to demonstrate more than 90% durable reduction in particulate matter (PM) and NOx emissions on a light-duty truck application, based on the FTP-75 drive cycle. Very low sulfur diesel fuel (<15 ppm-wt) enabled lower PM emissions, reduced fuel economy penalty due to the emission control system and improved long-term system durability. Significant progress was made toward a durable system to meet Tier 2 Bin 5 emission standards on a 6000 lbs light-duty truck. A 40% reduction in engine-out NOx emissions was achieved with a mid-size prototype diesel engine through engine recalibration and increased exhaust gas recirculation. Use of a rapid warm-up strategy and urea SCR provided over 90% further NOx reduction while the CDPF reduced tailpipe PM to gasoline vehicle levels. Development work was conducted to separately improve urea SCR and CDPF system durability, as well as improved oxidation catalyst function. Exhaust gas NOx and ammonia sensors were also developed further. While the final emission control system did not meet Tier 2 Bin 5 NOx after 120k mi of aging on the dynamometer, it did meet the standards for HC, NMOG, and PM, and an improved SCR catalyst was shown to have potential to meet the NOx standard, assuming the DOC durability could be improved further. Models of DOC and SCR function were developed to guide the study of several key

  5. Advances in Future Computer and Control Systems v.2

    CERN Document Server

    Lin, Sally; 2012 International Conference on Future Computer and Control Systems(FCCS2012)

    2012-01-01

    FCCS2012 is an integrated conference concentrating its focus on Future Computer and Control Systems. “Advances in Future Computer and Control Systems” presents the proceedings of the 2012 International Conference on Future Computer and Control Systems(FCCS2012) held April 21-22,2012, in Changsha, China including recent research results on Future Computer and Control Systems of researchers from all around the world.

  6. Advances in Future Computer and Control Systems v.1

    CERN Document Server

    Lin, Sally; 2012 International Conference on Future Computer and Control Systems(FCCS2012)

    2012-01-01

    FCCS2012 is an integrated conference concentrating its focus on Future Computer and Control Systems. “Advances in Future Computer and Control Systems” presents the proceedings of the 2012 International Conference on Future Computer and Control Systems(FCCS2012) held April 21-22,2012, in Changsha, China including recent research results on Future Computer and Control Systems of researchers from all around the world.

  7. Advanced Integrated Power and Attitude Control System (IPACS) study

    Science.gov (United States)

    Oglevie, R. E.; Eisenhaure, D. B.

    1985-01-01

    Integrated Power and Attitude Control System (IPACS) studies performed over a decade ago established the feasibility of simultaneously satisfying the demands of energy storage and attitude control through the use of rotating flywheels. It was demonstrated that, for a wide spectrum of applications, such a system possessed many advantages over contemporary energy storage and attitude control approaches. More recent technology advances in composite material rotors, magnetic suspension systems, and power control electronics have triggered new optimism regarding the applicability and merits of this concept. This study is undertaken to define an advanced IPACS and to evaluate its merits for a space station application. System and component designs are developed to establish the performance of this concept and system trade studies conducted to examine the viability of this approach relative to conventional candidate systems. It is clearly demonstrated that an advanced IPACS concept is not only feasible, but also offers substantial savings in mass and life-cycle cost for the space station mission.

  8. Development of the NSTX-U Advanced Divertor Control

    Science.gov (United States)

    Vail, Patrick; Kolemen, Egemen

    2016-10-01

    Advanced magnetic divertor configurations such as the snowflake (SF) divertor are being investigated at NSTX-U for reducing the peak heat flux onto plasma-facing components. Initial efforts include development of plasma scenarios incorporating SF configurations using an upgraded set of divertor coils as well as implementation of a feedback control system for real-time detection and manipulation of two closely-spaced magnetic null points. Closed-loop plasma simulations are performed to demonstrate precise control of various SF configurations. The simulations are then used to demonstrate that the controller can be enhanced to regulate additional parameters such as strike point location and divertor flux expansion. The advanced divertor control will be used in the coming years to enable experiments investigating the physics of advanced divertors at NSTX-U. Supported by the US DOE under DE-AC02-09CH11466.

  9. Advanced control room evaluation: General approach and rationale

    Energy Technology Data Exchange (ETDEWEB)

    O' Hara, J.M. (Brookhaven National Lab., Upton, NY (USA)); Wachtel, J. (Nuclear Regulatory Commission, Washington, DC (USA))

    1991-01-01

    Advanced control rooms (ACRs) for future nuclear power plants (NPPs) are being designed utilizing computer-based technologies. The US Nuclear Regulatory Commission reviews the human engineering aspects of such control rooms to ensure that they are designed to good human factors engineering principles and that operator performance and reliability are appropriately supported in order to protect public health and safety. This paper describes the rationale and general approach to the development of a human factors review guideline for ACRs. The factors influencing the guideline development are discussed, including the review environment, the types of advanced technologies being addressed, the human factors issues associated with advanced technology, and the current state-of-the-art of human factors guidelines for advanced human-system interfaces (HSIs). The proposed approach to ACR review would track the design and implementation process through the application of review guidelines reflecting four review modules: planning, design process analysis, human factors engineering review, and dynamic performance evaluation. 21 refs.

  10. Advanced Controller for the Free-Piston Stirling Convertor

    Science.gov (United States)

    Gerber, Scott S.; Jamison, Mike; Roth, Mary Ellen; Regan, Timothy F.

    2004-01-01

    The free-piston Stirling power convertor is being considered as an advanced power conversion technology to be used for future NASA deep space missions requiring long life radioisotope power systems. This technology has a conversion efficiency of over 25%, which is significantly higher than the efficiency of the Radioisotope Thermal-electric Generators (RTG) now in use. The NASA Glenn Research Center has long been recognized as a leader in Stirling technology and is responsible for the development of advanced technologies that are intended to significantly improve key characteristics of the Stirling convertor. The advanced technologies identified for development also consider the requirements of potential future missions and the new capabilities that have become available in the associated technical areas. One of the key areas identified for technology development is the engine controller. To support this activity, an advanced controller is being developed for the Stirling power convertor. This controller utilizes active power factor correction electronics and microcontroller-based controls. The object of this paper is to present an overview of the advanced controller concept with modeling, simulation and hardware test data.

  11. Controlling adsorbate interactions for advanced chemical patterning

    Science.gov (United States)

    Saavedra Garcia, Hector M.

    Molecules designed to have specific interactions were used to influence the structural, physical, and chemical properties of self-assembled monolayers. In the case of 1-adamantanethiolate monolayers, the molecular structure influences lability, enabling alkanethiol molecules in solution to displace the 1-adamantanethiolate monolayers, ultimately leading to complete molecular exchange. The similar Au-S bond environments measured for both n-alkanethiolate and 1-adamantanethiolate monolayers indicate that displacement is not a result of weakened Au-S bonds. Instead, it was hypothesized that the density differences in the two monolayers provide a substantial enthalpic driver, aided by differences in van der Waals forces, ultimately leading to complete displacement of the 1-adamantenthiol molecules. Additionally, it was discovered that displacement occurs via fast insertion of n-dodecanethiolate at the defects in the original 1-adamantanethiolate monolayer, which nucleates an island growth phase and is followed by slow ordering of the n-dodecanethiolate domains into a denser and more crystalline form. Langmuir-based kinetics, which describe alkanethiolate adsorption on bare Au{111}, fail to model this displacement reaction. Instead, a model of perimeter-dependent island growth yields good agreement with kinetic data over a 100-fold variation in n-dodecanethiol concentration. Rescaling the growth rate at each concentration collapses all the data onto a single universal curve, suggesting that displacement is a scale-free process. Exploiting the knowledge gained by studying 1-adamantethiolate monolayer displacement, a reversible molecular resist was developed, in which displacement is controlled via external stimuli. This methodology for the fabrication of controllably displaceable monolayers relies on carboxyl-functionalized self-assembled monolayers and in-situ Fischer esterification. Using an 11-mercaptoundecanoic acid monolayer as a model system, it was shown that in

  12. Advances in Multi-Pollutant Control

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2013-11-01

    Pollutants, such as nitrogen oxides (nitrogen dioxide (NO2) and nitric oxide (NO)), sulphur dioxide (SO2), sulphur trioxide (SO3), carbon dioxide (CO2), mercury (Hg) and particulate matter (PM), are formed when coal is combusted in a power plant boiler. With the concern over the environmental and health consequences of these pollutants, legislation and regulations have been implemented limiting the amounts that can be emitted to the atmosphere. Emission control systems on conventional coal-fired power plants typically employ technologies designed to remove one specific pollutant.These are then combined, in series, to remove several pollutants in order to meet the emission regulations. This report discusses multi-pollutant systems which remove two or more of the principal regulated pollutants (SO2, NOx, mercury, particulate matter and CO2) in a single reactor or a single system designed for the purpose. The emphasis is on commercial or near commercial processes, and those that are under active development. Ways to improve the co-benefit removal of oxidised mercury in conventional limestone wet scrubbers, spray dry scrubbers and circulating dry scrubbers are also included. Multi-pollutant systems can have lower capital and operating costs than a series of traditional systems to remove the s ame number of pollutants. Nevertheless, many of the multi-pollutant technologies rely on by-product sales to be economically competitive. Their footprint is often smaller than conventional single pollutant counterparts treating a similar volume of flue gas, making them easier to install in retrofit applications. Some of the systems use modular designs that ensures easy scalability for larger boilers.

  13. Recent Advances in Explicit Multiparametric Nonlinear Model Predictive Control

    KAUST Repository

    Domínguez, Luis F.

    2011-01-19

    In this paper we present recent advances in multiparametric nonlinear programming (mp-NLP) algorithms for explicit nonlinear model predictive control (mp-NMPC). Three mp-NLP algorithms for NMPC are discussed, based on which novel mp-NMPC controllers are derived. The performance of the explicit controllers are then tested and compared in a simulation example involving the operation of a continuous stirred-tank reactor (CSTR). © 2010 American Chemical Society.

  14. ADVANCED COMPRESSOR ENGINE CONTROLS TO ENHANCE OPERATION, RELIABILITY AND INTEGRITY

    Energy Technology Data Exchange (ETDEWEB)

    Gary D. Bourn; Jess W. Gingrich; Jack A. Smith

    2004-03-01

    This document is the final report for the ''Advanced Compressor Engine Controls to Enhance Operation, Reliability, and Integrity'' project. SwRI conducted this project for DOE in conjunction with Cooper Compression, under DOE contract number DE-FC26-03NT41859. This report addresses an investigation of engine controls for integral compressor engines and the development of control strategies that implement closed-loop NOX emissions feedback.

  15. A formal structure for advanced automatic flight-control systems

    Science.gov (United States)

    Meyer, G.; Cicolani, L. S.

    1975-01-01

    Techniques were developed for the unified design of multimode, variable authority automatic flight-control systems for powered-lift STOL and VTOL aircraft. A structure for such systems is developed to deal with the strong nonlinearities inherent in this class of aircraft, to admit automatic coupling with advanced air traffic control, and to admit a variety of active control tasks. The aircraft being considered is the augmentor wing jet STOL research aircraft.

  16. Advanced control of piezoelectric micro-nano-positioning systems

    CERN Document Server

    Xu, Qingsong

    2016-01-01

    This book explores emerging methods and algorithms that enable precise control of micro-/nano-positioning systems. The text describes three control strategies: hysteresis-model-based feedforward control and hysteresis-model-free feedback control based on and free from state observation. Each paradigm receives dedicated attention within a particular part of the text. Readers are shown how to design, validate and apply a variety of new control approaches in micromanipulation: hysteresis modelling, discrete-time sliding-mode control and model-reference adaptive control. Experimental results are provided throughout and build up to a detailed treatment of practical applications in the fourth part of the book. The applications focus on control of piezoelectric grippers. Advanced Control of Piezoelectric Micro-/Nano-Positioning Systems will assist academic researchers and practising control and mechatronics engineers interested in suppressing sources of nonlinearity such as hysteresis and drift when combining positi...

  17. Practical Implementations of Advanced Process Control for Linear Systems

    DEFF Research Database (Denmark)

    Knudsen, Jørgen K . H.; Huusom, Jakob Kjøbsted; Jørgensen, John Bagterp

    2013-01-01

    Most advanced process control systems are based on Model Predictive Control (MPC). In this paper we discuss three critical issues for the practical implementation of linear MPC for process control applications. The rst issue is related to oset free control and disturbance models; the second issue...... implications for process control. If the control and evaluation intervals are chosen too short, the predicted behaviour of the controllers may have unstable characteristics. Depending of the degrees of freedom, oset-free control of a number of the controlled variables can be achieved by introduction of noise...... models and integration of the innovation errors. If the disturbances increases, oset-free control cannot be achieved without violation of process constraints. A target calculation function is used to calculate the optimal achievable target for the process. The use of soft constraints for process output...

  18. AC electric motors control advanced design techniques and applications

    CERN Document Server

    Giri, Fouad

    2013-01-01

    The complexity of AC motor control lies in the multivariable and nonlinear nature of AC machine dynamics. Recent advancements in control theory now make it possible to deal with long-standing problems in AC motors control. This text expertly draws on these developments to apply a wide range of model-based control designmethods to a variety of AC motors. Contributions from over thirty top researchers explain how modern control design methods can be used to achieve tight speed regulation, optimal energetic efficiency, and operation reliability and safety, by considering online state var

  19. Contributions of CCLM to advances in quality control.

    Science.gov (United States)

    Kazmierczak, Steven C

    2013-01-01

    Abstract The discipline of laboratory medicine is relatively young when considered in the context of the history of medicine itself. The history of quality control, within the context of laboratory medicine, also enjoys a relatively brief, but rich history. Laboratory quality control continues to evolve along with advances in automation, measurement techniques and information technology. Clinical Chemistry and Laboratory Medicine (CCLM) has played a key role in helping disseminate information about the proper use and utility of quality control. Publication of important advances in quality control techniques and dissemination of guidelines concerned with laboratory quality control has undoubtedly helped readers of this journal keep up to date on the most recent developments in this field.

  20. Advanced and intelligent control in power electronics and drives

    CERN Document Server

    Blaabjerg, Frede; Rodríguez, José

    2014-01-01

    Power electronics and variable frequency drives are continuously developing multidisciplinary fields in electrical engineering, and it is practically not possible to write a book covering the entire area by one individual specialist. Especially by taking account the recent fast development in the neighboring fields like control theory, computational intelligence and signal processing, which all strongly influence new solutions in control of power electronics and drives. Therefore, this book is written by individual key specialist working on the area of modern advanced control methods which penetrates current implementation of power converters and drives. Although some of the presented methods are still not adopted by industry, they create new solutions with high further research and application potential. The material of the book is presented in the following three parts: Part I: Advanced Power Electronic Control in Renewable Energy Sources (Chapters 1-4), Part II: Predictive Control of Power Converters and D...

  1. A survey on control schemes for distributed solar collector fields. Part II: Advanced control approaches

    Energy Technology Data Exchange (ETDEWEB)

    Camacho, E.F.; Rubio, F.R. [Universidad de Sevilla, Escuela Superior de Ingenieros, Departamento de Ingenieria de Sistemas y Automatica, Camino de Los Descubrimientos s/n, E-41092 Sevilla (Spain); Berenguel, M. [Universidad de Almeria, Departamento de Lenguajes y Computacion, Area de Ingenieria de Sistemas y Automatica, Carretera Sacramento s/n, E-04120 La Canada, Almeria (Spain); Valenzuela, L. [Plataforma Solar de Almeria - CIEMAT, Carretera Senes s/n, P.O. Box 22, E-04200 Tabernas (Almeria) (Spain)

    2007-10-15

    This article presents a survey of the different advanced automatic control techniques that have been applied to control the outlet temperature of solar plants with distributed collectors during the last 25 years. A classification of the modeling and control approaches described in the first part of this survey is used to explain the main features of each strategy. The treated strategies range from classical advanced control strategies to those with few industrial applications. (author)

  2. Vision Based Autonomous Robotic Control for Advanced Inspection and Repair

    Science.gov (United States)

    Wehner, Walter S.

    2014-01-01

    The advanced inspection system is an autonomous control and analysis system that improves the inspection and remediation operations for ground and surface systems. It uses optical imaging technology with intelligent computer vision algorithms to analyze physical features of the real-world environment to make decisions and learn from experience. The advanced inspection system plans to control a robotic manipulator arm, an unmanned ground vehicle and cameras remotely, automatically and autonomously. There are many computer vision, image processing and machine learning techniques available as open source for using vision as a sensory feedback in decision-making and autonomous robotic movement. My responsibilities for the advanced inspection system are to create a software architecture that integrates and provides a framework for all the different subsystem components; identify open-source algorithms and techniques; and integrate robot hardware.

  3. Improving Advanced Inverter Control Convergence in Distribution Power Flow

    Energy Technology Data Exchange (ETDEWEB)

    Nagarajan, Adarsh; Palmintier, Bryan; Ding, Fei; Mather, Barry; Baggu, Murali

    2016-11-21

    Simulation of modern distribution system powerflow increasingly requires capturing the impact of advanced PV inverter voltage regulation on powerflow. With Volt/var control, the inverter adjusts its reactive power flow as a function of the point of common coupling (PCC) voltage. Similarly, Volt/watt control curtails active power production as a function of PCC voltage. However, with larger systems and higher penetrations of PV, this active/reactive power flow itself can cause significant changes to the PCC voltage potentially introducing oscillations that slow the convergence of system simulations. Improper treatment of these advanced inverter functions could potentially lead to incorrect results. This paper explores a simple approach to speed such convergence by blending in the previous iteration's reactive power estimate to dampen these oscillations. Results with a single large (5MW) PV system and with multiple 500kW advanced inverters show dramatic improvements using this approach.

  4. Comparison of Advanced Distillation Control Methods, Final Technical Report

    Energy Technology Data Exchange (ETDEWEB)

    Dr. James B. Riggs

    2000-11-30

    Detailed dynamic simulations of three industrial distillation columns (a propylene/propane splitter, a xylene/toluene column, and a depropanizer) have been used to evaluate configuration selections for single-ended and dual-composition control, as well as to compare conventional and advanced control approaches. In addition, a simulator of a main fractionator was used to compare the control performance of conventional and advanced control. For each case considered, the controllers were tuned by using setpoint changes and tested using feed composition upsets. Proportional Integral (PI) control performance was used to evaluate the configuration selection problem. For single ended control, the energy balance configuration was found to yield the best performance. For dual composition control, nine configurations were considered. It was determined that the use of dynamic simulations is required in order to identify the optimum configuration from among the nine possible choices. The optimum configurations were used to evaluate the relative control performance of conventional PI controllers, MPC (Model Predictive Control), PMBC (Process Model-Based Control), and ANN (Artificial Neural Networks) control. It was determined that MPC works best when one product is much more important than the other, while PI was superior when both products were equally important. PMBC and ANN were not found to offer significant advantages over PI and MPC. MPC was found to outperform conventional PI control for the main fractionator. MPC was applied to three industrial columns: one at Phillips Petroleum and two at Union Carbide. In each case, MPC was found to significantly outperform PI controls. The major advantage of the MPC controller is its ability to effectively handle a complex set of constraints and control objectives.

  5. The advanced main control console for next japanese PWR plants

    Energy Technology Data Exchange (ETDEWEB)

    Tsuchiya, A. [Hokkaido Electric Power Co., Inc., Sapporo (Japan); Ito, K. [Mitsubishi Heavy Industries, Ltd., Nuclear Energy Systems Engineering Center, Yokohama (Japan); Yokoyama, M. [Mitsubishi Electric Corporation, Energy and Industrial Systems Center, Kobe (Japan)

    2001-07-01

    The purpose of the improvement of main control room designing in a nuclear power plant is to reduce operators' workload and potential human errors by offering a better working environment where operators can maximize their abilities. In order to satisfy such requirements, the design of main control board applied to Japanese Pressurized Water Reactor (PWR) type nuclear power plant has been continuously modified and improved. the Japanese Pressurized Water Reactor (PWR) Utilities (Electric Power Companies) and Mitsubishi Group have developed an advanced main control board (console) reflecting on the study of human factors, as well as using a state of the art electronics technology. In this report, we would like to introduce the configuration and features of the Advanced Main Control Console for the practical application to the next generation PWR type nuclear power plants including TOMARI No.3 Unit of Hokkaido Electric Power Co., Inc. (author)

  6. Advances in developing alternative treatments for postharvest pest control

    Science.gov (United States)

    USDA-ARS made two significant advances in the last 10 years in the development of alternative treatments for postharvest pest control: oxygenated phosphine fumigation and nitric oxide fumigation. Oxygenated phosphine is phosphine fumigation in an oxygen enriched atmosphere. It is significantly more...

  7. Controlling death: the false promise of advance directives.

    Science.gov (United States)

    Perkins, Henry S

    2007-07-03

    Advance directives promise patients a say in their future care but actually have had little effect. Many experts blame problems with completion and implementation, but the advance directive concept itself may be fundamentally flawed. Advance directives simply presuppose more control over future care than is realistic. Medical crises cannot be predicted in detail, making most prior instructions difficult to adapt, irrelevant, or even misleading. Furthermore, many proxies either do not know patients' wishes or do not pursue those wishes effectively. Thus, unexpected problems arise often to defeat advance directives, as the case in this paper illustrates. Because advance directives offer only limited benefit, advance care planning should emphasize not the completion of directives but the emotional preparation of patients and families for future crises. The existentialist Albert Camus might suggest that physicians should warn patients and families that momentous, unforeseeable decisions lie ahead. Then, when the crisis hits, physicians should provide guidance; should help make decisions despite the inevitable uncertainties; should share responsibility for those decisions; and, above all, should courageously see patients and families through the fearsome experience of dying.

  8. Application of infinite model predictive control methodology to other advanced controllers.

    Science.gov (United States)

    Abu-Ayyad, M; Dubay, R; Hernandez, J M

    2009-01-01

    This paper presents an application of most recent developed predictive control algorithm an infinite model predictive control (IMPC) to other advanced control schemes. The IMPC strategy was derived for systems with different degrees of nonlinearity on the process gain and time constant. Also, it was shown that IMPC structure uses nonlinear open-loop modeling which is conducted while closed-loop control is executed every sampling instant. The main objective of this work is to demonstrate that the methodology of IMPC can be applied to other advanced control strategies making the methodology generic. The IMPC strategy was implemented on several advanced controllers such as PI controller using Smith-Predictor, Dahlin controller, simplified predictive control (SPC), dynamic matrix control (DMC), and shifted dynamic matrix (m-DMC). Experimental work using these approaches combined with IMPC was conducted on both single-input-single-output (SISO) and multi-input-multi-output (MIMO) systems and compared with the original forms of these advanced controllers. Computer simulations were performed on nonlinear plants demonstrating that the IMPC strategy can be readily implemented on other advanced control schemes providing improved control performance. Practical work included real-time control applications on a DC motor, plastic injection molding machine and a MIMO three zone thermal system.

  9. Supervisory Control System Architecture for Advanced Small Modular Reactors

    Energy Technology Data Exchange (ETDEWEB)

    Cetiner, Sacit M [ORNL; Cole, Daniel L [University of Pittsburgh; Fugate, David L [ORNL; Kisner, Roger A [ORNL; Melin, Alexander M [ORNL; Muhlheim, Michael David [ORNL; Rao, Nageswara S [ORNL; Wood, Richard Thomas [ORNL

    2013-08-01

    This technical report was generated as a product of the Supervisory Control for Multi-Modular SMR Plants project within the Instrumentation, Control and Human-Machine Interface technology area under the Advanced Small Modular Reactor (SMR) Research and Development Program of the U.S. Department of Energy. The report documents the definition of strategies, functional elements, and the structural architecture of a supervisory control system for multi-modular advanced SMR (AdvSMR) plants. This research activity advances the state-of-the art by incorporating decision making into the supervisory control system architectural layers through the introduction of a tiered-plant system approach. The report provides a brief history of hierarchical functional architectures and the current state-of-the-art, describes a reference AdvSMR to show the dependencies between systems, presents a hierarchical structure for supervisory control, indicates the importance of understanding trip setpoints, applies a new theoretic approach for comparing architectures, identifies cyber security controls that should be addressed early in system design, and describes ongoing work to develop system requirements and hardware/software configurations.

  10. Stringent theoretical and experimental bounds on graviton mass

    CERN Document Server

    Ali, Ahmed Farag

    2016-01-01

    We show from theoretical considerations, that if the graviton is massive, its mass is constrained to be about $10^{-32}~eV/c^2$. This estimate is consistent with those obtained from experiments, including the recent gravitational wave detection in advanced LIGO.

  11. The DPC-2000 advanced control system for the Dynamitron accelerator

    Science.gov (United States)

    Kestler, Bernard A.; Lisanti, Thomas F.

    1993-07-01

    The DPC-2000 is an advanced control system utilizing the latest technology in computer control circuitry and components. Its overall design is modular and technologically advanced to keep up with customer and engineering demands. The full control system is presented as four units. They are the Remote I/O (Input / Output), Local Analog and Digital I/O, Operator Interface and the Main Computer. The central processing unit, the heart of the system, executes a high level language program that communicates to the different sub-assemblies through advanced serial and parallel communication lines. All operational parameters of the accelerator are monitored, controlled and corrected at close to 20 times per second. The operator is provided with a selection of many informative screen displays. The control program handles all graphic screen displays and the updating of these screens directly; it does not have to communicate to a display terminal. This adds to the quick response and excellent operator feedback received while operating the machine. The CPU also has the ability to store and record all process variable setpoints for each product that will be treated. This allows the operator to set up the process parameters by selecting the product identification code from a menu presented on the display screen. All process parameters are printed to report at regular intervals during a process run for later analysis and record keeping.

  12. Material Protection, Accounting, and Control Technologies (MPACT) Advanced Integration Roadmap

    Energy Technology Data Exchange (ETDEWEB)

    Miller, Mike [Idaho National Lab. (INL), Idaho Falls, ID (United States); Cipiti, Ben [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Demuth, Scott Francis [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Durkee, Jr., Joe W. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Fallgren, Andrew James [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Jarman, Ken [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Li, Shelly [Idaho National Lab. (INL), Idaho Falls, ID (United States); Meier, Dave [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Osburn, Laura Ann [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Pereira, Candido [Argonne National Lab. (ANL), Argonne, IL (United States); Dasari, Venkateswara Rao [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Ticknor, Lawrence O. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Yoo, Tae-Sic [Idaho National Lab. (INL), Idaho Falls, ID (United States)

    2017-01-30

    The development of sustainable advanced nuclear fuel cycles is a long-term goal of the Office of Nuclear Energy’s (DOE-NE) Fuel Cycle Technologies program. The Material Protection, Accounting, and Control Technologies (MPACT) campaign is supporting research and development (R&D) of advanced instrumentation, analysis tools, and integration methodologies to meet this goal (Miller, 2015). This advanced R&D is intended to facilitate safeguards and security by design of fuel cycle facilities. The lab-scale demonstration of a virtual facility, distributed test bed, that connects the individual tools being developed at National Laboratories and university research establishments, is a key program milestone for 2020. These tools will consist of instrumentation and devices as well as computer software for modeling, simulation and integration.

  13. Material Protection, Accounting, and Control Technologies (MPACT) Advanced Integration Roadmap

    Energy Technology Data Exchange (ETDEWEB)

    Durkee, Joe W. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Cipiti, Ben [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Demuth, Scott Francis [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Fallgren, Andrew James [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Jarman, Ken [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Li, Shelly [Argonne National Lab. (ANL), Argonne, IL (United States); Meier, Dave [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Miller, Mike [Argonne National Lab. (ANL), Argonne, IL (United States); Osburn, Laura Ann [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Pereira, Candido [Argonne National Lab. (ANL), Argonne, IL (United States); Dasari, Venkateswara Rao [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Ticknor, Lawrence O. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Yoo, Tae-Sic [Argonne National Lab. (ANL), Argonne, IL (United States)

    2016-09-30

    The development of sustainable advanced nuclear fuel cycles is a long-term goal of the Office of Nuclear Energy’s (DOE-NE) Fuel Cycle Technologies program. The Material Protection, Accounting, and Control Technologies (MPACT) campaign is supporting research and development (R&D) of advanced instrumentation, analysis tools, and integration methodologies to meet this goal (Miller, 2015). This advanced R&D is intended to facilitate safeguards and security by design of fuel cycle facilities. The lab-scale demonstration of a virtual facility, distributed test bed, that connects the individual tools being developed at National Laboratories and university research establishments, is a key program milestone for 2020. These tools will consist of instrumentation and devices as well as computer software for modeling, simulation and integration.

  14. Distributed Information Fusion through Advanced Multi-Agent Control

    Science.gov (United States)

    2016-09-09

    AFRL-AFOSR-JP-TR-2016-0080 Distributed Information Fusion through Advanced Multi-Agent Control Adrian Bishop NATIONAL ICT AUSTRALIA LIMITED Final...a currently valid OMB control number. PLEASE DO NOT RETURN YOUR FORM TO THE ABOVE ORGANIZATION. 1. REPORT DATE (DD-MM-YYYY)      17-10-2016 2. REPORT... Control 5a.  CONTRACT NUMBER 5b.  GRANT NUMBER FA2386-14-1-4042 5c.  PROGRAM ELEMENT NUMBER 61102F 6. AUTHOR(S) Adrian Bishop 5d.  PROJECT NUMBER 5e

  15. Microeconomics of advanced process window control for 50-nm gates

    Science.gov (United States)

    Monahan, Kevin M.; Chen, Xuemei; Falessi, Georges; Garvin, Craig; Hankinson, Matt; Lev, Amir; Levy, Ady; Slessor, Michael D.

    2002-07-01

    Fundamentally, advanced process control enables accelerated design-rule reduction, but simple microeconomic models that directly link the effects of advanced process control to profitability are rare or non-existent. In this work, we derive these links using a simplified model for the rate of profit generated by the semiconductor manufacturing process. We use it to explain why and how microprocessor manufacturers strive to avoid commoditization by producing only the number of dies required to satisfy the time-varying demand in each performance segment. This strategy is realized using the tactic known as speed binning, the deliberate creation of an unnatural distribution of microprocessor performance that varies according to market demand. We show that the ability of APC to achieve these economic objectives may be limited by variability in the larger manufacturing context, including measurement delays and process window variation.

  16. Practical Implementations of Advanced Process Control for Linear Systems

    DEFF Research Database (Denmark)

    Knudsen, Jørgen K . H.; Huusom, Jakob Kjøbsted; Jørgensen, John Bagterp

    This paper describes some practical problems encountered, when implementing Advanced Process Control, APC, schemes on linear processes. The implemented APC controllers discussed will be LQR, Riccati MPC and Condensed MPC controllers illustrated by simulation of the Four Tank Process...... cannot be achieved without violation of process constraints. A target calculation function can be used to calculate the optimal achievable target for the process. The use of hard and soft constraints for process input constraints in the MPC controllers, ensures feasible solutions. The computational load...... as function of controllers type, Model dimension and constraint type will be discussed. Finally the special requirements set by processes including a pure integration dynamics will be illustrated by a linearised CSTR process. The simulated results presented, will later on be implemented on and demonstrated...

  17. Recent advances in opinion modeling: control and social influence

    CERN Document Server

    Albi, Giacomo; Toscani, Giuseppe; Zanella, Mattia

    2016-01-01

    We survey some recent developments on the mathematical modeling of opinion dynamics. After an introduction on opinion modeling through interacting multi-agent systems described by partial differential equations of kinetic type, we focus our attention on two major advancements: optimal control of opinion formation and influence of additional social aspects, like conviction and number of connections in social networks, which modify the agents' role in the opinion exchange process.

  18. Control Systems with Saturating Inputs Analysis Tools and Advanced Design

    CERN Document Server

    Corradini, Maria Letizia; Giannoni, Fabio; Orlando, Giuseppe

    2012-01-01

    This series aims to report new developments in the fields of control and information sciences - quickly, informally and at a high level. The type of material considered for publication includes: 1. Preliminary drafts of monographs and advanced textbooks 2. Lectures on a new field, or presenting a new angle on a classical field 3. Research reports 4. Reports of meetings, provided they are a) of exceptional interest and b) devoted to a specific topic. The timeliness of subject material is very important.

  19. Advanced Control Design for Wind Turbines; Part I: Control Design, Implementation, and Initial Tests

    Energy Technology Data Exchange (ETDEWEB)

    Wright, A. D.; Fingersh, L. J.

    2008-03-01

    The purpose of this report is to give wind turbine engineers information and examples of the design, testing through simulation, field implementation, and field testing of advanced wind turbine controls.

  20. Advanced Rooftop Control (ARC) Retrofit: Field-Test Results

    Energy Technology Data Exchange (ETDEWEB)

    Wang, Weimin; Katipamula, Srinivas; Ngo, Hung; Underhill, Ronald M.; Taasevigen, Danny J.; Lutes, Robert G.

    2013-07-31

    The multi-year research study was initiated to find solutions to improve packaged equipment operating efficiency in the field. Pacific Northwest National Laboratory (PNNL), with funding from the U.S. Department of Energy’s (DOE’s) Building Technologies Office (BTO) and Bonneville Power Administration (BPA) conducted this research, development and demonstration (RD&D) study. Packaged equipment with constant speed supply fans is designed to provide ventilation at the design rate at all times when the fan is operating as required by building code. Although there are a number of hours during the day when a building may not be fully occupied or the need for ventilation is lower than designed, the ventilation rate cannot be adjusted easily with a constant speed fan. Therefore, modulating the supply fan in conjunction with demand controlled ventilation (DCV) will not only reduce the coil energy but also reduce the fan energy. The objective of this multi-year research, development and demonstration project was to determine the magnitude of energy savings achievable by retrofitting existing packaged rooftop air conditioners with advanced control strategies not ordinarily used for packaged units. First, through detailed simulation analysis, it was shown that significant energy (between 24% and 35%) and cost savings (38%) from fan, cooling and heating energy consumption could be realized when packaged air conditioning units with gas furnaces are retrofitted with advanced control packages (combining multi-speed fan control, integrated economizer controls and DCV). The simulation analysis also showed significant savings for heat pumps (between 20% and 60%). The simulation analysis was followed by an extensive field test of a retrofittable advanced rooftop unit (RTU) controller.

  1. Application of advanced polymeric materials for controlled release pesticides

    Science.gov (United States)

    Rahim, M.; Hakim, M. R.; Haris, H. M.

    2016-08-01

    The objective of this work was to study the capability of advanced polymeric material constituted by chitosan and natural rubber matrices for controlled release of pesticides (1-hydroxynaphthalene and 2-hydroxynaphthalene) in aqueous solution. The released amount of pesticides was measured spectrophotometrically from the absorbance spectra applying a standardized curve. The release of the pesticides was studied into refreshing and non-refreshing neutral aqueous media. Interestingly, formulation successfully indicated a consistent, controlled and prolonged release of pesticides over a period of 35 days.

  2. Coal surface control for advanced physical fine coal cleaning technologies

    Energy Technology Data Exchange (ETDEWEB)

    Morsi, B.I.; Chiang, S.H.; Sharkey, A.; Blachere, J.; Klinzing, G.; Araujo, G.; Cheng, Y.S.; Gray, R.; Streeter, R.; Bi, H.; Campbell, P.; Chiarlli, P.; Ciocco, M.; Hittle, L.; Kim, S.; Kim, Y.; Perez, L.; Venkatadri, R.

    1992-01-01

    This final report presents the research work carried out on the Coal Surface Control for Advanced Physical Fine Coal Cleaning Technologies project, sponsored by the US Department of Energy, Pittsburgh Energy Technology Center (DOE/PETC). The project was to support the engineering development of the selective agglomeration technology in order to reduce the sulfur content of US coals for controlling SO[sub 2] emissions (i.e., acid rain precursors). The overall effort was a part of the DOE/PETCs Acid Rain Control Initiative (ARCI). The overall objective of the project is to develop techniques for coal surface control prior to the advanced physical fine coal cleaning process of selective agglomeration in order to achieve 85% pyrite sulfur rejection at an energy recovery greater than 85% based on run-of-mine coal. The surface control is meant to encompass surface modification during grinding and laboratory beneficiation testing. The project includes the following tasks: Project planning; methods for analysis of samples; development of standard beneficiation test; grinding studies; modification of particle surface; and exploratory R D and support. The coal samples used in this project include three base coals, Upper Freeport - Indiana County, PA, Pittsburgh NO. 8 - Belmont County, OH, and Illinois No. 6 - Randolph County, IL, and three additional coals, Upper Freeport - Grant County- WV, Kentucky No. 9 Hopkins County, KY, and Wyodak - Campbell County, WY. A total of 149 drums of coal were received.

  3. Recent Advances in the Control of Piezoelectric Actuators

    Directory of Open Access Journals (Sweden)

    Ziqiang Chi

    2014-11-01

    Full Text Available The micro/nano positioning field has made great progress towards enabling the advance of micro/nano technology. Micro/nano positioning stages actuated by piezoelectric actuators are the key devices in micro/nano manipulation. The control of piezoelectric actuators has emerged as a hot topic in recent years. Piezoelectric materials have inherent hysteresis and creep nonlinearity, which can reduce the accuracy of the manipulation, even causing the instability of the whole system. Remarkable efforts have been made to compensate for the nonlinearity of piezoelectric actuation through the mathematical modelling and control approaches. This paper provides a review of recent advances on the control of piezoelectric actuators. After a brief introduction of basic components of typical piezoelectric micro/nano positioning platforms, the working principle and modelling of piezoelectric actuators are outlined in this paper. This is followed with the major control method and recent progress is presented in detail. Finally, some open issues and future work on the control of piezoelectric actuators are extensively discussed.

  4. Recent Advances in the Control of Piezoelectric Actuators

    Directory of Open Access Journals (Sweden)

    Ziqiang Chi

    2014-11-01

    Full Text Available The micro/nano positioning field has made great progress towards enabling the advance of micro/nano technology. Micro/nano positioning stages actuated by piezoelectric actuators are the key devices in micro/nano manipulation. The control of piezoelectric actuators has emerged as a hot topic in recent years. Piezoelectric materials have inherent hysteresis and creep nonlinearity, which can reduce the accuracy of the manipulation, even causing the instability of the whole system. Remarkable efforts have been made to compensate for the nonlinearity of piezoelectric actuation through the mathematical modelling and control approaches. This paper provides a review of recent advances on the control of piezoelectric actuators. After a brief introduction of basic components of typical piezoelectric micro/nano positioning platforms, the working principle and modelling of piezoelectric actuators are outlined in this paper. This is followed with the major control method and recent progress is presented in detail. Finally, some open issues and future work on the control of piezoelectric actuators are extensively discussed.

  5. Evaluation of information display at advanced main control room

    Energy Technology Data Exchange (ETDEWEB)

    Min, Dae Hwan; Yu, Seon Jae; Choi, Eui Sun [Korea Univ., Seoul (Korea, Republic of)

    2000-03-15

    This year we plan to survey information in order to have basic understanding of digital information display and control at the advanced MCR. At first we collect different ways of presenting information at the advanced MCR. Secondly, we conduct literature survey on studies that have investigated information representation techniques and their effects. Then, we need compare differences between conventional NPPs and advanced NPPs. Thirdly, we need to check HMI styles and evaluation techniques that are used currently at foreign NPPs. Indeed, HMI at the advanced MCR is quite different from that at a conventional MCR. It is not desirable to apply the same evaluation technique that has veen used at the conventional MCR. We need to develop an evaluation technique that is valid in theory and applicable in practice. Finally, we identify the requirements for a support system for an HMI evaluator, since it is not easy to carry out an evaluation task even though one has firm background on cognitive engineering theories and practical experiences.

  6. Control Design for an Advanced Geared Turbofan Engine

    Science.gov (United States)

    Chapman, Jeffryes W.; Litt, Jonathan

    2017-01-01

    This paper describes the design process for the control system of an advanced geared turbofan engine. This process is applied to a simulation that is representative of a 30,000 lbf thrust class concept engine with two main spools, ultra-high bypass ratio, and a variable area fan nozzle. Control system requirements constrain the non-linear engine model as it operates throughout its flight envelope of sea level to 40,000 ft and from 0 to 0.8 Mach. The control architecture selected for this project was developed from literature and reflects a configuration that utilizes a proportional integral controller integrated with sets of limiters that enable the engine to operate safely throughout its flight envelope. Simulation results show the overall system meets performance requirements without exceeding system operational limits.

  7. The Advanced Photon Source Injector Test Stand Control System

    CERN Document Server

    MacLean, J F

    2001-01-01

    The Advanced Photon Source (APS) primary and backup injectors consist of two thermionic-cathode rf guns. These guns are being upgraded to provide improved performance, to improve ease of maintenance, and to reduce downtime required for repair or replacement of a failed injector. As part of the process, an injector test stand is being prepared. This stand is effectively independent of the APS linac and will allow for complete characterization and validation of an injector prior to its installation into the APS linac. A modular control system for the test stand has been developed using standard APS control solutions with EPICS to deliver a flexible and comprehensive control system. The modularity of the system will allow both the future expansion of test stand functionality and the evaluation of new control techniques and solutions.

  8. Integrated metrology: an enabler for advanced process control (APC)

    Science.gov (United States)

    Schneider, Claus; Pfitzner, Lothar; Ryssel, Heiner

    2001-04-01

    Advanced process control (APC) techniques become more and more important as short innovation cycles in microelectronics and a highly competitive market requires cost-effective solutions in semiconductor manufacturing. APC marks a paradigm shift from statistically based techniques (SPC) using monitor wafers for sampling measurement data towards product wafer control. The APC functionalities including run-to-run control, fault detection, and fault analysis allow to detect process drifts and excursions at an early stage and to minimize the number of misprocessed wafers. APC is being established as part of factory control systems through the definition of an APC framework. A precondition for APC is the availability of sensors and measurement methods providing the necessary wafer data. This paper discusses integrated metrology as an enabler for APC and demonstrates practical implementations in semiconductor manufacturing.

  9. Advances in Intelligent Control Systems and Computer Science

    CERN Document Server

    2013-01-01

    The conception of real-time control networks taking into account, as an integrating approach, both the specific aspects of information and knowledge processing and the dynamic and energetic particularities of physical processes and of communication networks is representing one of the newest scientific and technological challenges. The new paradigm of Cyber-Physical Systems (CPS) reflects this tendency and will certainly change the evolution of the technology, with major social and economic impact. This book presents significant results in the field of process control and advanced information and knowledge processing, with applications in the fields of robotics, biotechnology, environment, energy, transportation, et al.. It introduces intelligent control concepts and strategies as well as real-time implementation aspects for complex control approaches. One of the sections is dedicated to the complex problem of designing software systems for distributed information processing networks. Problems as complexity an...

  10. Refinements and Tests of an Advanced Controller to Mitigate Fatigue Loads in the Controls Advanced Research Turbine: Preprint

    Energy Technology Data Exchange (ETDEWEB)

    Wright, A.; Fleming, P.

    2010-12-01

    Wind turbines are complex, nonlinear, dynamic systems forced by aerodynamic, gravitational, centrifugal, and gyroscopic loads. The aerodynamics of wind turbines are nonlinear, unsteady, and complex. Turbine rotors are subjected to a complicated 3-D turbulent wind inflow field, with imbedded coherent vortices that drive fatigue loads and reduce lifetime. Design of control algorithms for wind turbines must account for multiple control objectives. Future large multi-megawatt turbines must be designed with lighter weight structures, using active controls to mitigate fatigue loads, while maximizing energy capture. Active damping should be added to these dynamic structures to maintain stability for operation in a complex environment. At the National Renewable Energy Laboratory (NREL), we have designed, implemented, and tested advanced controls to maximize energy extraction and reduce structural dynamic loads. These control designs are based on linear models of the turbine that are generated by specialized modeling software. In this paper, we present field test results of an advanced control algorithm to mitigate blade, tower, and drivetrain loads in Region 3.

  11. Advances Towards the Measurement and Control of LHC Tune and Chromaticity

    CERN Document Server

    Cameron, P; Degen, C; Della Penna, A; Hoff, L T; Mead, J; Sikora, R

    2005-01-01

    Requirements for tune and chromaticity control in most superconducting hadron machines, and in particular the LHC, are stringent. In order to reach nominal operation, the LHC will almost certainly require feedback on both tune and chromaticity. Experience at RHIC has also shown that coupling control is crucial to successful tune feedback. A prototype baseband PLL tune measurement system, intended for the LHC, has recently been brought into operation at RHIC. We report on the performance of that system and compare it with the extensive accumulation of data from the RHIC 245MHz PLL. In addition the implementation of coupling and chromaticity feedback using PLL systems will be discussed.

  12. Advanced Controller Developed for the Free-Piston Stirling Convertor

    Science.gov (United States)

    Gerber, Scott S.

    2005-01-01

    A free-piston Stirling power convertor is being considered as an advanced power-conversion technology for future NASA deep-space missions requiring long-life radioisotope power systems. The NASA Glenn Research Center has identified key areas where advanced technologies can enhance the capability of Stirling energy-conversion systems. One of these is power electronic controls. Current power-conversion technology for Glenn-tested Stirling systems consists of an engine-driven linear alternator generating an alternating-current voltage controlled by a tuning-capacitor-based alternating-current peak voltage load controller. The tuning capacitor keeps the internal alternator electromotive force (EMF) in phase with its respective current (i.e., passive power factor correction). The alternator EMF is related to the piston velocity, which must be kept in phase with the alternator current in order to achieve stable operation. This tuning capacitor, which adds volume and mass to the overall Stirling convertor, can be eliminated if the controller can actively drive the magnitude and phase of the alternator current.

  13. Advanced discrete-time control designs and applications

    CERN Document Server

    Abidi, Khalid

    2015-01-01

    This book covers a wide spectrum of systems such as linear and nonlinear multivariable systems as well as control problems such as disturbance, uncertainty and time-delays. The purpose of this book is to provide researchers and practitioners a manual for the design and application of advanced discrete-time controllers.  The book presents six different control approaches depending on the type of system and control problem. The first and second approaches are based on Sliding Mode control (SMC) theory and are intended for linear systems with exogenous disturbances. The third and fourth approaches are based on adaptive control theory and are aimed at linear/nonlinear systems with periodically varying parametric uncertainty or systems with input delay. The fifth approach is based on Iterative learning control (ILC) theory and is aimed at uncertain linear/nonlinear systems with repeatable tasks and the final approach is based on fuzzy logic control (FLC) and is intended for highly uncertain systems with heuristi...

  14. Artificial Intelligent Control for a Novel Advanced Microwave Biodiesel Reactor

    Energy Technology Data Exchange (ETDEWEB)

    Wali, W A; Hassan, K H; Cullen, J D; Al-Shamma' a, A I; Shaw, A; Wylie, S R, E-mail: w.wali@2009.ljmu.ac.uk [Built Environment and Sustainable Technologies Institute (BEST), School of the Built Environment, Faculty of Technology and Environment Liverpool John Moores University, Byrom Street, Liverpool L3 3AF (United Kingdom)

    2011-08-17

    Biodiesel, an alternative diesel fuel made from a renewable source, is produced by the transesterification of vegetable oil or fat with methanol or ethanol. In order to control and monitor the progress of this chemical reaction with complex and highly nonlinear dynamics, the controller must be able to overcome the challenges due to the difficulty in obtaining a mathematical model, as there are many uncertain factors and disturbances during the actual operation of biodiesel reactors. Classical controllers show significant difficulties when trying to control the system automatically. In this paper we propose a comparison of artificial intelligent controllers, Fuzzy logic and Adaptive Neuro-Fuzzy Inference System(ANFIS) for real time control of a novel advanced biodiesel microwave reactor for biodiesel production from waste cooking oil. Fuzzy logic can incorporate expert human judgment to define the system variables and their relationships which cannot be defined by mathematical relationships. The Neuro-fuzzy system consists of components of a fuzzy system except that computations at each stage are performed by a layer of hidden neurons and the neural network's learning capability is provided to enhance the system knowledge. The controllers are used to automatically and continuously adjust the applied power supplied to the microwave reactor under different perturbations. A Labview based software tool will be presented that is used for measurement and control of the full system, with real time monitoring.

  15. Artificial Intelligent Control for a Novel Advanced Microwave Biodiesel Reactor

    Science.gov (United States)

    Wali, W. A.; Hassan, K. H.; Cullen, J. D.; Al-Shamma'a, A. I.; Shaw, A.; Wylie, S. R.

    2011-08-01

    Biodiesel, an alternative diesel fuel made from a renewable source, is produced by the transesterification of vegetable oil or fat with methanol or ethanol. In order to control and monitor the progress of this chemical reaction with complex and highly nonlinear dynamics, the controller must be able to overcome the challenges due to the difficulty in obtaining a mathematical model, as there are many uncertain factors and disturbances during the actual operation of biodiesel reactors. Classical controllers show significant difficulties when trying to control the system automatically. In this paper we propose a comparison of artificial intelligent controllers, Fuzzy logic and Adaptive Neuro-Fuzzy Inference System(ANFIS) for real time control of a novel advanced biodiesel microwave reactor for biodiesel production from waste cooking oil. Fuzzy logic can incorporate expert human judgment to define the system variables and their relationships which cannot be defined by mathematical relationships. The Neuro-fuzzy system consists of components of a fuzzy system except that computations at each stage are performed by a layer of hidden neurons and the neural network's learning capability is provided to enhance the system knowledge. The controllers are used to automatically and continuously adjust the applied power supplied to the microwave reactor under different perturbations. A Labview based software tool will be presented that is used for measurement and control of the full system, with real time monitoring.

  16. DSP applications in advanced, intelligent motion control: the future

    Energy Technology Data Exchange (ETDEWEB)

    Beierke, S. [Texas Instruments Deutschland GmBh, Freising (Germany); Vas, P. [Univ. of Aberdeen, Dept. of Engineering (United Kingdom)

    2000-08-01

    Recently there has been a rapid increase in the number of DSPs for various motion control applications. However, in the future, further significant increase is expected due to wider applications in existing and new areas (e.g. household appliances, automotive auxiliaries, micro-electromechanical systems, military applications, etc.). The present paper discusses the state-of-art Texas Instruments fixed point and floating point DSPs used in motion control applications and will also focus on future activities. Currently new chip technologies are being developed which involve copper interconnects, silicon-on-insulator wafers, insulators with- low dielectric constants, etc. It is expected that future single-chip DSPs for advanced intelligent motion control will have higher performance, reduced costs, simpler designs, will incorporate various sensors, different modules for optimised PWM generation, efficiency control, vector and direct torque control (sensorless and quasisensorless solutions as well), condition monitoring, selfcommissioning, artificial-intelligence-based control, etc. A manufacturer's task of implementing sensorless and/or quasisensorless torque control schemes for induction, synchronous and switched reluctance motor drives will be significantly reduced by the application of the newly developed DSPs. The paper will discuss these issues and will also show some implementation results in various sensorless (classical DTC; DTC with torque-ripple reduction schemes; vector) and quasisensorless ac drives (e.g. a vector controlled induction motor drive). (orig.)

  17. Integration of advanced teleoperation technologies for control of space robots

    Science.gov (United States)

    Stagnaro, Michael J.

    1993-01-01

    Teleoperated robots require one or more humans to control actuators, mechanisms, and other robot equipment given feedback from onboard sensors. To accomplish this task, the human or humans require some form of control station. Desirable features of such a control station include operation by a single human, comfort, and natural human interfaces (visual, audio, motion, tactile, etc.). These interfaces should work to maximize performance of the human/robot system by streamlining the link between human brain and robot equipment. This paper describes development of a control station testbed with the characteristics described above. Initially, this testbed will be used to control two teleoperated robots. Features of the robots include anthropomorphic mechanisms, slaving to the testbed, and delivery of sensory feedback to the testbed. The testbed will make use of technologies such as helmet mounted displays, voice recognition, and exoskeleton masters. It will allow tor integration and testing of emerging telepresence technologies along with techniques for coping with control link time delays. Systems developed from this testbed could be applied to ground control of space based robots. During man-tended operations, the Space Station Freedom may benefit from ground control of IVA or EVA robots with science or maintenance tasks. Planetary exploration may also find advanced teleoperation systems to be very useful.

  18. Advances and applications in sliding mode control systems

    CERN Document Server

    Zhu, Quanmin

    2015-01-01

    This book describes the advances and applications in Sliding mode control (SMC) which is widely used as a powerful method to tackle uncertain nonlinear systems. The book is organized into 21 chapters which have been organised by the editors to reflect the various themes of sliding mode control. The book provides the reader with a broad range of material from first principles up to the current state of the art in the area of SMC and observation presented in a clear, matter-of-fact style. As such it is appropriate for graduate students with a basic knowledge of classical control theory and some knowledge of state-space methods and nonlinear systems. The resulting design procedures are emphasized using Matlab/Simulink software.    

  19. Advanced Control of Photovoltaic and Wind Turbines Power Systems

    DEFF Research Database (Denmark)

    Yang, Yongheng; Chen, Wenjie; Blaabjerg, Frede

    2014-01-01

    Much more efforts have been made on the integration of renewable energies into the grid in order to meet the imperative demand of a clean and reliable electricity generation. In this case, the grid stability and robustness may be violated due to the intermittency and interaction of the solar...... and wind renewables. Thus, in this chapter, advanced control strategies, which can enable the power conversion efficiently and reliably, for both photovoltaic (PV) and wind turbines power systems are addressed in order to enhance the integration of those technologies. Related grid demands have been...... power injection for both single-phase and three-phase systems. Other control strategies like constant power generation control for PV systems to further increase the penetration level, and the improvements of LVRT performance for a doubly fed induction generator based wind turbine system by means...

  20. Benchmarking of Advanced Control Strategies for a Simulated Hydroelectric System

    Science.gov (United States)

    Finotti, S.; Simani, S.; Alvisi, S.; Venturini, M.

    2017-01-01

    This paper analyses and develops the design of advanced control strategies for a typical hydroelectric plant during unsteady conditions, performed in the Matlab and Simulink environments. The hydraulic system consists of a high water head and a long penstock with upstream and downstream surge tanks, and is equipped with a Francis turbine. The nonlinear characteristics of hydraulic turbine and the inelastic water hammer effects were considered to calculate and simulate the hydraulic transients. With reference to the control solutions addressed in this work, the proposed methodologies rely on data-driven and model-based approaches applied to the system under monitoring. Extensive simulations and comparisons serve to determine the best solution for the development of the most effective, robust and reliable control tool when applied to the considered hydraulic system.

  1. Advanced Fuzzy Logic Based Admission Control for UMTS System

    Directory of Open Access Journals (Sweden)

    P. Kejik

    2010-12-01

    Full Text Available The capacity of CDMA (Code Division Multiple Access systems is interference limited. Therefore radio resources management (RRM functions are used. They are responsible for supplying optimum coverage, ensuring efficient use of physical resources, and providing the maximum planned capacity. This paper deals with admission control techniques for UMTS (Universal Mobile Telecommunication System. A UMTS system model and four fuzzy logic based admission control algorithms are presented in this paper. Two new versions of fuzzy logic based admission control algorithms are presented there. All algorithms are mutually compared via simulations. Simulations show that the novel advanced fuzzy algorithm outperforms the other simulated algorithms (in terms of blocking probability, dropping probability and the number of active UEs in cell.

  2. Advanced Energy Harvesting Control Schemes for Marine Renewable Energy Devices

    Energy Technology Data Exchange (ETDEWEB)

    McEntee, Jarlath [Ocean Renewable Power Company, Portland, ME (United States); Polagye, Brian [Ocean Renewable Power Company, Portland, ME (United States); Fabien, Brian [Ocean Renewable Power Company, Portland, ME (United States); Thomson, Jim [Ocean Renewable Power Company, Portland, ME (United States); Kilcher, Levi [Ocean Renewable Power Company, Portland, ME (United States); Marnagh, Cian [Ocean Renewable Power Company, Portland, ME (United States); Donegan, James [Ocean Renewable Power Company, Portland, ME (United States)

    2016-03-31

    The Advanced Energy Harvesting Control Schemes for Marine Renewable Energy Devices (Project) investigated, analyzed and modeled advanced turbine control schemes with the objective of increasing the energy harvested by hydrokinetic turbines in turbulent flow. Ocean Renewable Power Company (ORPC) implemented and validated a feedforward controller to increase power capture; and applied and tested the controls on ORPC’s RivGen® Power Systems in Igiugig, Alaska. Assessments of performance improvements were made for the RivGen® in the Igiugig environment and for ORPC’s TidGen® Power System in a reference tidal environment. Annualized Energy Production (AEP) and Levelized Cost of Energy (LCOE) improvements associated with implementation of the recommended control methodology were made for the TidGen® Power System in the DOE reference tidal environment. System Performance Advancement (SPA) goals were selected for the project. SPA targets were to improve Power to Weight Ratio (PWR) and system Availability, with the intention of reducing Levelized Cost of Electricity (LCOE). This project focused primarily reducing in PWR. Reductions in PWR of 25.5% were achieved. Reductions of 20.3% in LCOE were achieved. This project evaluated four types of controllers which were tested in simulation, emulation, a laboratory flume, and the field. The adaptive Kω2 controller performs similarly to the non-adaptive version of the same controller and may be useful in tidal channels where the mean velocity is continually evolving. Trends in simulation were largely verified through experiments, which also provided the opportunity to test assumptions about turbine responsiveness and control resilience to varying scales of turbulence. Laboratory experiments provided an essential stepping stone between simulation and implementation on a field-scale turbine. Experiments also demonstrated that using “energy loss” as a metric to differentiate between well-designed controllers operating at

  3. Advanced Controls for the Multi-pod Centipod WEC device

    Energy Technology Data Exchange (ETDEWEB)

    McCall, Alan [Dehlsen Associates, LLC, Santa Barabara, CA (United States); Fleming, Alex [Dehlsen Associates, LLC, Santa Barabara, CA (United States)

    2016-02-15

    Dehlsen Associates, LLC (DA) has developed a Wave Energy Converter (WEC), Centipod, which is a multiple point absorber, extracting wave energy primarily in the heave direction through a plurality of point absorber floats sharing a common stable reference structure. The objective of this project was to develop advanced control algorithms that will be used to reduce Levelized Cost of Energy (LCOE). This project investigated the use of Model Predictive Control (MPC) to improve the power capture of the WEC. The MPC controller developed in this work is a state-space, “look ahead” controller approach using knowledge of past and current states to predict future states to take action with the PTO to maximize power capture while still respecting system constraints. In order to maximize power, which is the product of force and velocity, the controller must aim to create phase alignment between excitation force and velocity. This project showed a 161% improvement in the Annual Energy Production (AEP) for the Centipod WEC when utilizing MPC, compared to a baseline, fixed passive damping control strategy. This improvement in AEP was shown to provide a substantial benefit to the WEC’s overall Cost of Energy, reducing LCOE by 50% from baseline. The results of this work proved great potential for the adoption of Model Predictive Controls in Wave Energy Converters.

  4. PREFACE: European Workshop on Advanced Control and Diagnosis

    Science.gov (United States)

    Schulte, Horst; Georg, Sören

    2014-12-01

    The European Workshop on Advanced Control and Diagnosis is an annual event that has been organised since 2003 by Control Engineering departments of several European universities in Germany, France, the UK, Poland, Italy, Hungary and Denmark. The overall planning of the workshops is conducted by the Intelligent Control and Diagnosis (ICD) steering committee. This year's ACD workshop took place at HTW Berlin (University of Applied Sciences) and was organised by the Control Engineering group of School of Engineering I of HTW Berlin. 38 papers were presented at ACD 2014, with contributions spanning a variety of fields in modern control science: Discrete control, nonlinear control, model predictive control, system identification, fault diagnosis and fault-tolerant control, control applications, applications of fuzzy logic, as well as modelling and simulation, the latter two forming a basis for all tasks in modern control. Three interesting and high-quality plenary lectures were delivered. The first plenary speaker was Wolfgang Weber from Pepperl+Fuchs, a German manufacturer of state-of-the-art industrial sensors and process interfaces. The second and third plenary speakers were two internationally high-ranked researchers in their respective fields, Prof. Didier Theilliol from Université de Lorraine and Prof. Carsten Scherer from Universität Stuttgart. Taken together, the three plenary lectures sought to contribute to closing the gap between theory and applications. On behalf of the whole ACD 2014 organising committee, we would like to thank all those who submitted papers and participated in the workshop. We hope it was a fruitful and memorable event for all. Together we are looking forward to the next ACD workshop in 2015 in Pilsen, Czech Republic. Horst Schulte (General Chair), Sören Georg (Programme Chair)

  5. Controlled Human Malaria Infection: Applications, Advances and Challenges.

    Science.gov (United States)

    Stanisic, Danielle I; McCarthy, James S; Good, Michael F

    2017-09-18

    Controlled Human Malaria Infection (CHMI) entails deliberate infection with malaria parasites either by mosquito bite or direct injection of sporozoites or parasitised erythrocytes. When required, the resulting blood-stage infection is curtailed by the administration of anti-malarial drugs. Inducing a malaria infection via inoculation with infected blood was first used as a treatment (malariotherapy) for neurosyphilis in Europe and the United States in the early 1900s. More recently, CHMI has been applied to the fields of malaria vaccine and drug development where it is used to evaluate products in well-controlled early phase proof-of-concept clinical studies thus facilitating progression of only the most promising candidates for further evaluation in malaria-endemic areas. Controlled infections have also been used to immunise against malaria infection. Historically, CHMI studies have been restricted by the need for access to insectaries housing infected mosquitoes or suitable malaria-infected individuals. Evaluation of vaccine and drug candidates has been constrained in these studies by the availability of a limited number of P. falciparum isolates. Recent advances have included cryopreservation of sporozoites, the manufacture of well characterised and genetically distinct cultured malaria cell banks for blood-stage infection, and P. vivax-specific reagents. These advances will help to accelerate malaria vaccine and drug development by making the reagents for CHMI more widely accessible and also enabling a more rigorous evaluation with multiple parasite strains and species. Here we discuss the different applications of CHMI, recent advances in the use of CHMI and ongoing challenges for consideration. Copyright © 2017 American Society for Microbiology.

  6. Coal surface control for advanced fine coal flotation

    Energy Technology Data Exchange (ETDEWEB)

    Fuerstenau, D.W.; Hanson, J.S.; Diao, J.; Harris, G.H.; De, A.; Sotillo, F. (California Univ., Berkeley, CA (United States)); Somasundaran, P.; Harris, C.C.; Vasudevan, T.; Liu, D.; Li, C. (Columbia Univ., New York, NY (United States)); Hu, W.; Zou, Y.; Chen, W. (Utah Univ., Salt Lake City, UT (United States)); Choudhry, V.; Shea, S.; Ghosh, A.; Sehgal, R. (Praxis Engineers, Inc., Milpitas, CA (United States))

    1992-03-01

    The initial goal of the research project was to develop methods of coal surface control in advanced froth flotation to achieve 90% pyritic sulfur rejection, while operating at Btu recoveries above 90% based on run-of-mine quality coal. Moreover, the technology is to concomitantly reduce the ash content significantly (to six percent or less) to provide a high-quality fuel to the boiler (ash removal also increases Btu content, which in turn decreases a coal's emission potential in terms of lbs SO{sub 2}/million Btu). (VC)

  7. Design of an AdvancedTCA board management controller (IPMC)

    Science.gov (United States)

    Mendez, J.; Bobillier, V.; Haas, S.; Joos, M.; Mico, S.; Vasey, F.

    2017-03-01

    The AdvancedTCA (ATCA) standard has been selected as the hardware platform for the upgrade of the back-end electronics of the CMS and ATLAS experiments of the Large Hadron Collider (LHC) . In this context, the electronic systems for experiments group at CERN is running a project to evaluate, specify, design and support xTCA equipment. As part of this project, an Intelligent Platform Management Controller (IPMC) for ATCA blades, based on a commercial solution, has been designed to be used on existing and future ATCA blades. This paper reports on the status of this project presenting the hardware and software developments.

  8. Advanced Transport Operating System (ATOPS) control display unit software description

    Science.gov (United States)

    Slominski, Christopher J.; Parks, Mark A.; Debure, Kelly R.; Heaphy, William J.

    1992-01-01

    The software created for the Control Display Units (CDUs), used for the Advanced Transport Operating Systems (ATOPS) project, on the Transport Systems Research Vehicle (TSRV) is described. Module descriptions are presented in a standardized format which contains module purpose, calling sequence, a detailed description, and global references. The global reference section includes subroutines, functions, and common variables referenced by a particular module. The CDUs, one for the pilot and one for the copilot, are used for flight management purposes. Operations performed with the CDU affects the aircraft's guidance, navigation, and display software.

  9. Advances in control of ectoparasites in large animals.

    Science.gov (United States)

    Hiepe, T

    1988-11-01

    In continuation of a publication on "Large-scale management systems and parasite populations: ectoparasites" in Vet. Parasitol. 11 (1982): 61-68, advances and present state of the control of ectoparasites in herds of cattle, sheep and camels are discussed. An intensified animal production necessitates permanent veterinary control of the status of ectoparasites. Strategically, control is basically directed towards achieving three aims: eradication, reduction of losses by means of dilution of ectoparasites regulations, and therapeutic measures. In the last few years, important progress has been made in effective ectoparasites control, mainly resulting from the discovery of new insecticides and acaricides, the improvement of the application techniques and the recent results in the biological control of arthropods; finally, an immunological approach will open new alternative ways of control. The control of mange and demodicosis in cattle; sarcoptic mange and sucking lice infestations in pigs; mange, biting lice infestations and nasal bots in sheep; ectoparasite infestations in camels and tick infestations are the main topics of the paper. The discovery of Ivermectin, a derivate of Streptomyces avermitilis which is now already fully integrated in to the spectrum of antiparasitic drugs, created a new generation of broad spectrum insecticides/acaricides. Current problems of the chemical control of arthropods, like the risk of residues in meat, milk and their products, the insecticide resistance and the possible environment pollution are critically outlined. But on the other hand, it can be predicted hypothetically that the amount of pest control measures in farm animals will increase in the near future to eliminate arthropods as causes of skin diseases and of damages to hides entailing negative effects on leather processing and as vectors of important infection agents. Finally, the proposal is submitted to elaborate international control programmes against ectoparasite

  10. Advanced Off-Gas Control System Design For Radioactive And Mixed Waste Treatment

    Energy Technology Data Exchange (ETDEWEB)

    Nick Soelberg

    2005-09-01

    Treatment of radioactive and mixed wastes is often required to destroy or immobilize hazardous constituents, reduce waste volume, and convert the waste to a form suitable for final disposal. These kinds of treatments usually evolve off-gas. Air emission regulations have become increasingly stringent in recent years. Mixed waste thermal treatment in the United States is now generally regulated under the Hazardous Waste Combustor (HWC) Maximum Achievable Control Technology (MACT) standards. These standards impose unprecedented requirements for operation, monitoring and control, and emissions control. Off-gas control technologies and system designs that were satisfactorily proven in mixed waste operation prior to the implementation of new regulatory standards are in some cases no longer suitable in new mixed waste treatment system designs. Some mixed waste treatment facilities have been shut down rather than have excessively restrictive feed rate limits or facility upgrades to comply with the new standards. New mixed waste treatment facilities in the U. S. are being designed to operate in compliance with the HWC MACT standards. Activities have been underway for the past 10 years at the INL and elsewhere to identify, develop, demonstrate, and design technologies for enabling HWC MACT compliance for mixed waste treatment facilities. Some specific off-gas control technologies and system designs have been identified and tested to show that even the stringent HWC MACT standards can be met, while minimizing treatment facility size and cost.

  11. A Stringent Authorization using Principles and Policy for Grid Computing

    Directory of Open Access Journals (Sweden)

    A. R. Jayasudha

    2011-01-01

    Full Text Available Problem statement: The current information security mechanisms are insufficient to address authorization issues. The access control models today are mostly static and they are not wellsuited for the service-oriented environments where information access is dynamic in nature. Traditional authorization security techniques do not directly address these concerns as they primarily use access control lists for authorization, where the user whose name appears in the list is authorized to access the grid with some privileges associated with the names, which requires the resource provider to maintain authorization decisions for every user, which is very time consuming and non-scalable solution. Approach: Organizations pass user roles instead of name and date of birth but it used Public Key Infrastructure user certificate for authorization which is inflexible when it comes to open distributed systems (Grid as it assumes a pre-agreed trust between Service Provider and the Service consumer. Usage of Java authentication and authorization services is performed in a pluggable fashion. It permits the application to remain independent from underlying authentication technology. Results: Our implementation provides service providers with full control over authentication and authorization of accounts that access services. Implementation of the proposed technique has proved to be less time consuming and more secured for authentication and authorization as compared to the traditional way of authenticating the users. The Policy Decision Service is envisioned to be used by many Web services protected by their PEPs. Conclusion: The model brings out many advantages over traditional identity. It is more flexible and more powerful and is suited for dynamic environments for Web services.

  12. Advanced Thermo-Adsorptive Battery: Advanced Thermo-Adsorptive Battery Climate Control System

    Energy Technology Data Exchange (ETDEWEB)

    None

    2011-12-31

    HEATS Project: MIT is developing a low-cost, compact, high-capacity, advanced thermoadsorptive battery (ATB) for effective climate control of EVs. The ATB provides both heating and cooling by taking advantage of the materials’ ability to adsorb a significant amount of water. This efficient battery system design could offer up as much as a 30% increase in driving range compared to current EV climate control technology. The ATB provides high-capacity thermal storage with little-to-no electrical power consumption. The ATB is also looking to explore the possibility of shifting peak electricity loads for cooling and heating in a variety of other applications, including commercial and residential buildings, data centers, and telecom facilities.

  13. Mercury Control With The Advanced Hybrid Paticulate Collector

    Energy Technology Data Exchange (ETDEWEB)

    Stanley J. Miller; Ye Zhuang; Jay Almlie

    2004-09-30

    This project was awarded under U.S. Department of Energy (DOE) National Energy Technology Laboratory (NETL) Program Solicitation DE-PS26-00NT40769 and specifically addresses Technical Topical Area 4 - Testing Novel and Less Mature Control Technologies on Actual Flue Gas at the Pilot Scale. The project team included the Energy & Environmental Research Center (EERC) as the main contractor; W.L. Gore & Associates, Inc., as a technical and financial partner; and the Big Stone Plant operated by Otter Tail Power Company, host for the field-testing portion of the research. Since 1995, DOE has supported development of a new concept in particulate control called the advanced hybrid particulate collector (AHPC). The AHPC has been licensed to W.L. Gore and Associates, Inc., and is marketed as the Advanced Hybrid{trademark} filter by Gore. The AHPC combines the best features of electrostatic precipitators (ESPs) and baghouses in a unique configuration, providing major synergism between the two collection methods, both in the particulate collection step and in the transfer of dust to the hopper. The AHPC provides ultrahigh collection efficiency, overcoming the problem of excessive fine-particle emissions with conventional ESPs, and it solves the problem of reentrainment and re-collection of dust in conventional baghouses. The AHPC also appears to have unique advantages for mercury control over baghouses or ESPs as an excellent gas-solid contactor. The objective of the original 5-task project was to demonstrate 90% total mercury control in the AHPC at a lower cost than current mercury control estimates. The approach included bench-scale batch tests, larger-scale pilot testing with real flue gas on a coal-fired combustion system, and field demonstration at the 2.5-MW scale at a utility power plant to prove scale-up and demonstrate longer-term mercury control. The scope of work was modified to include an additional sixth task, initiated in April 2003. The objective of this task

  14. Second Generation Advanced Reburning for High Efficiency NOx Control

    Energy Technology Data Exchange (ETDEWEB)

    Vladimir M. Zamansky; Pete M. Maly; Vitali V. Lissianski

    2000-12-31

    This project is designed to develop a family of novel NO{sub x} control technologies, called Second Generation Advanced Reburning (SGAR) which has the potential to achieve 90+% NO{sub x} control in coal-fired boilers at a significantly lower cost than SCR. The thirteenth reporting period in Phase II (October 1-December 31, 2000) included SGAR tests in which coal was used as the reburning fuel. All test work was conducted at GE-EER's 1.0 MMBtu/hr Boiler Simulator Facility. Three test series were performed including AR-Lean, AR-Rich, and reburning + SNCR. Tests demonstrated that over 90% NO{sub x} reduction could be achieved with utilization of coal as a reburning fuel in SGAR. The most effective SGAR variant is reburning + SNCR followed by AR-Lean and AR-Rich.

  15. MERCURY CONTROL WITH THE ADVANCED HYBRID PARTICULATE COLLECTOR

    Energy Technology Data Exchange (ETDEWEB)

    Ye Zhuang; Stanley J. Miller; Steven A. Benson; Michelle R. Olderbak

    2003-08-01

    This project was awarded under U.S. Department of Energy (DOE) National Energy Technology Laboratory (NETL) Program Solicitation DE-PS26-00NT40769 and specifically addresses Technical Topical Area 4-Testing Novel and Less Mature Control Technologies on Actual Flue Gas at the Pilot Scale. The project team includes the Energy & Environmental Research Center (EERC) as the main contractor; W.L. Gore & Associates, Inc., as a technical and financial partner; and the Big Stone Plant operated by Otter Tail Power Company, host for the field-testing portion of the research. Since 1995, DOE has supported development of a new concept in particulate control called the advanced hybrid particulate collector (AHPC). The AHPC has been licensed to W.L. Gore & Associates, Inc., and is now marketed as the ''Advanced Hybrid''{trademark} filter by Gore. The AHPC combines the best features of electrostatic precipitators (ESPs) and baghouses in a unique configuration, providing major synergism between the two collection methods, both in the particulate collection step and in the transfer of dust to the hopper. The AHPC provides ultra-high collection efficiency, overcoming the problem of excessive fine-particle emissions with conventional ESPs, and it solves the problem of reentrainment and re-collection of dust in conventional baghouses. The AHPC appears to have unique advantages for mercury control over baghouses or ESPs as an excellent gas-solid contactor. The objective of the three-task project is to demonstrate 90% total mercury control in the AHPC at a lower cost than current mercury control estimates. The approach includes bench-scale batch testing that ties the new work to previous results and links results with larger-scale pilot testing with real flue gas on a coal-fired combustion system, pilot-scale testing on a coal-fired combustion system with both a pulse-jet baghouse and an AHPC to prove or disprove the research hypotheses, and field demonstration pilot

  16. Advances in the control of mechatronic suspension systems

    Institute of Scientific and Technical Information of China (English)

    Wajdi SABOUD; Sallehuddin Mohamed HARIS; Yuzita YAACOB

    2014-01-01

    The suspension system is a key element in motor vehicles. Advancements in electronics and micropro-cessor technology have led to the realization of mechatronic suspensions. Since its introduction in some production motorcars in the 1980s, it has remained an area which sees active research and development, and this will likely continue for many years to come. With the aim of identifying current trends and future focus areas, this paper presents a review on the state-of-the-art of mechatronic suspensions. First, some commonly used classifications of mechatronic suspensions are presented. This is followed by a discussion on some of the actuating mechanisms used to provide control action. A survey is then reported on the many types of control approaches, including look-ahead preview, predictive, fuzzy logic, proportional-integral-derivative (PID), optimal, robust, adaptive, robust adaptive, and switching control. In conclusion, hydraulic actuators are most commonly used, but they impose high power requirements, limiting practical realizations of active suspensions. Electromagnetic actuators are seen to hold the promise of lower power requirements, and rigorous research and development should be conducted to make them commercially usable. Current focus on control methods that are robust to suspension parameter variations also seems to produce limited performance improvements, and future control approaches should be adaptive to the changeable driving conditions.

  17. Auxotrophy-based High Throughput Screening assay for the identification of Bacillus subtilis stringent response inhibitors

    Science.gov (United States)

    Andresen, Liis; Varik, Vallo; Tozawa, Yuzuru; Jimmy, Steffi; Lindberg, Stina; Tenson, Tanel; Hauryliuk, Vasili

    2016-01-01

    The stringent response is a central adaptation mechanism that allows bacteria to adjust their growth and metabolism according to environmental conditions. The functionality of the stringent response is crucial for bacterial virulence, survival during host invasion as well as antibiotic resistance and tolerance. Therefore, specific inhibitors of the stringent response hold great promise as molecular tools for disarming and pacifying bacterial pathogens. By taking advantage of the valine amino acid auxotrophy of the Bacillus subtilis stringent response-deficient strain, we have set up a High Throughput Screening assay for the identification of stringent response inhibitors. By screening 17,500 compounds, we have identified a novel class of antibacterials based on the 4-(6-(phenoxy)alkyl)-3,5-dimethyl-1H-pyrazole core. Detailed characterization of the hit compounds as well as two previously identified promising stringent response inhibitors – a ppGpp-mimic nucleotide Relacin and cationic peptide 1018 – showed that neither of the compounds is sufficiently specific, thus motivating future application of our screening assay to larger and more diverse molecular libraries. PMID:27775002

  18. AMBA Based Advanced DMA Controller for SoC

    Directory of Open Access Journals (Sweden)

    Abdullah Aljumah

    2016-03-01

    Full Text Available this paper describes the implementation of an AMBA Based Advanced DMA Controller for SoC. It uses AMBA Specifications, where two buses AHB and APB are defined and works for processor as system bus and peripheral bus respectively. The DMA controller functions between these two buses as a bridge and allow them to work concurrently. Depending on the speed of peripherals it uses buffering mechanism. Therefore an asynchronous FIFO is used for synchronizing the speed of peripherals. The proposed DMA controller can works in SoC along with processor and achieve fast data rate. The method introduced significant volume of data transfer with very low timing characteristics. Thus it is a better choice in respect of timing and volume of data. These two issues have been resolved under this research study. The results are compared with the AMD processors, like Geode GX 466, GX 500 and GX 533, and the presence and absence of DMA controller with processor is discussed and compared. The DMAC stands to be better alternative in SoC design.

  19. Advanced Energy Harvesting Control Schemes for Marine Renewable Energy Devices

    Energy Technology Data Exchange (ETDEWEB)

    McEntee, Jarlath [Ocean Renewable Power Company, Portland, ME (United States); Polagye, Brian [Ocean Renewable Power Company, Portland, ME (United States); Fabien, Brian [Ocean Renewable Power Company, Portland, ME (United States); Thomson, Jim [Ocean Renewable Power Company, Portland, ME (United States); Kilcher, Levi [Ocean Renewable Power Company, Portland, ME (United States); Marnagh, Cian [Ocean Renewable Power Company, Portland, ME (United States); Donegan, James [Ocean Renewable Power Company, Portland, ME (United States)

    2016-03-31

    The Advanced Energy Harvesting Control Schemes for Marine Renewable Energy Devices (Project) investigated, analyzed and modeled advanced turbine control schemes with the objective of increasing the energy harvested by hydrokinetic turbines in turbulent flow. Ocean Renewable Power Company (ORPC) implemented and validated a feedforward controller to increase power capture; and applied and tested the controls on ORPC’s RivGen® Power Systems in Igiugig, Alaska. Assessments of performance improvements were made for the RivGen® in the Igiugig environment and for ORPC’s TidGen® Power System in a reference tidal environment. Annualized Energy Production (AEP) and Levelized Cost of Energy (LCOE) improvements associated with implementation of the recommended control methodology were made for the TidGen® Power System in the DOE reference tidal environment. System Performance Advancement (SPA) goals were selected for the project. SPA targets were to improve Power to Weight Ratio (PWR) and system Availability, with the intention of reducing Levelized Cost of Electricity (LCOE). This project focused primarily reducing in PWR. Reductions in PWR of 25.5% were achieved. Reductions of 20.3% in LCOE were achieved. This project evaluated four types of controllers which were tested in simulation, emulation, a laboratory flume, and the field. The adaptive Kω2 controller performs similarly to the non-adaptive version of the same controller and may be useful in tidal channels where the mean velocity is continually evolving. Trends in simulation were largely verified through experiments, which also provided the opportunity to test assumptions about turbine responsiveness and control resilience to varying scales of turbulence. Laboratory experiments provided an essential stepping stone between simulation and implementation on a field-scale turbine. Experiments also demonstrated that using “energy loss” as a metric to differentiate between well-designed controllers operating at

  20. HFE safety reviews of advanced nuclear power plant control rooms

    Science.gov (United States)

    Ohara, John

    1994-01-01

    Advanced control rooms (ACR's) will utilize human-system interface (HSI) technologies that may have significant implications for plant safety in that they will affect the operator's overall role and means of interacting with the system. The Nuclear Regulatory Commission (NRC) reviews the human factors engineering (HFE) aspects of HSI's to ensure that they are designed to good HFE principles and support performance and reliability in order to protect public health and safety. However, the only available NRC guidance was developed more than ten years ago, and does not adequately address the human performance issues and technology changes associated with ACR's. Accordingly, a new approach to ACR safety reviews was developed based upon the concept of 'convergent validity'. This approach to ACR safety reviews is described.

  1. Advanced methods of microscope control using μManager software

    Directory of Open Access Journals (Sweden)

    Arthur D Edelstein

    2014-07-01

    Full Text Available µManager is an open-source, cross-platform desktop application, to control a wide variety of motorized microscopes, scientific cameras, stages, illuminators, and other microscope accessories. Since its inception in 2005, µManager has grown to support a wide range of microscopy hardware and is now used by thousands of researchers around the world. The application provides a mature graphical user interface and offers open programming interfaces to facilitate plugins and scripts. Here, we present a guide to using some of the recently added advanced µManager features, including hardware synchronization, simultaneous use of multiple cameras, projection of patterned light onto a specimen, live slide mapping, imaging with multi-well plates, particle localization and tracking, and high-speed imaging.

  2. Advanced methods of microscope control using μManager software.

    Science.gov (United States)

    Edelstein, Arthur D; Tsuchida, Mark A; Amodaj, Nenad; Pinkard, Henry; Vale, Ronald D; Stuurman, Nico

    μManager is an open-source, cross-platform desktop application, to control a wide variety of motorized microscopes, scientific cameras, stages, illuminators, and other microscope accessories. Since its inception in 2005, μManager has grown to support a wide range of microscopy hardware and is now used by thousands of researchers around the world. The application provides a mature graphical user interface and offers open programming interfaces to facilitate plugins and scripts. Here, we present a guide to using some of the recently added advanced μManager features, including hardware synchronization, simultaneous use of multiple cameras, projection of patterned light onto a specimen, live slide mapping, imaging with multi-well plates, particle localization and tracking, and high-speed imaging.

  3. Thermal Design to Meet Stringent Temperature Gradient/Stability Requirements of SWIFT BAT Detectors

    Science.gov (United States)

    Choi, Michael K.

    2000-01-01

    The Burst Alert Telescope (BAT) is an instrument on the National Aeronautics and Space Administration (NASA) SWIFT spacecraft. It is designed to detect gamma ray burst over a broad region of the sky and quickly align the telescopes on the spacecraft to the gamma ray source. The thermal requirements for the BAT detector arrays are very stringent. The maximum allowable temperature gradient of the 256 cadmium zinc telluride (CZT) detectors is PC. Also, the maximum allowable rate of temperature change of the ASICs of the 256 Detector Modules (DMs) is PC on any time scale. The total power dissipation of the DMs and Block Command & Data Handling (BCDH) is 180 W. This paper presents a thermal design that uses constant conductance heat pipes (CCHPs) to minimize the temperature gradient of the DMs, and loop heat pipes (LHPs) to transport the waste heat to the radiator. The LHPs vary the effective thermal conductance from the DMs to the radiator to minimize heater power to meet the heater power budget, and to improve the temperature stability. The DMs are cold biased, and active heater control is used to meet the temperature gradient and stability requirements.

  4. GPS based Advanced Vehicle Tracking and Vehicle Control System

    Directory of Open Access Journals (Sweden)

    Mashood Mukhtar

    2015-02-01

    Full Text Available Security systems and navigators have always been a necessity of human‟s life. The developments of advanced electronics have brought revolutionary changes in these fields. In this paper, we will present a vehicle tracking system that employs a GPS module and a GSM modem to find the location of a vehicle and offers a range of control features. To complete the design successfully, a GPS unit, two relays, a GSM Modem and two MCU units are used. There are five features introduced in the project. The aim of this project is to remotely track a vehicle‟s location, remotely switch ON and OFF the vehicle‟s ignition system and remotely lock and unlock the doors of the vehicle. An SMS message is sent to the tracking system and the system responds to the users request by performing appropriate actions. Short text messages are assigned to each of these features. A webpage is specifically designed to view the vehicle‟s location on Google maps. By using relay based control concept introduced in this paper, number of control features such as turning heater on/off, radio on/off etc. can be implemented in the same fashion.

  5. International conference on Advances in Intelligent Control and Innovative Computing

    CERN Document Server

    Castillo, Oscar; Huang, Xu; Intelligent Control and Innovative Computing

    2012-01-01

    In the lightning-fast world of intelligent control and cutting-edge computing, it is vitally important to stay abreast of developments that seem to follow each other without pause. This publication features the very latest and some of the very best current research in the field, with 32 revised and extended research articles written by prominent researchers in the field. Culled from contributions to the key 2011 conference Advances in Intelligent Control and Innovative Computing, held in Hong Kong, the articles deal with a wealth of relevant topics, from the most recent work in artificial intelligence and decision-supporting systems, to automated planning, modelling and simulation, signal processing, and industrial applications. Not only does this work communicate the current state of the art in intelligent control and innovative computing, it is also an illuminating guide to up-to-date topics for researchers and graduate students in the field. The quality of the contents is absolutely assured by the high pro...

  6. Staying competitive with advanced technologies for closed loop supervisory control

    Energy Technology Data Exchange (ETDEWEB)

    Radl, B.J.; Roland, W.B. [Pegasus Technologies Corp., Painesville, OH (United States); Kish, B. [Penn Power, New Castle, PA (United States)

    1996-05-01

    The following paper discusses the experience gained from installing a neural network-based supervisory control system for selected combustion parameters at Penn Power`s New Castle station. The primary goal of the program was to reduce NO{sub x} emissions, while maintaining or improving unit heat rate. The advanced technologies used to implement supervisory control include: Neural Networks, Genetic Algorithms, Pattern Recognition and Data Visualization. The program was jointly funded by Ohio Edison, U.S. Department of Energy (DOE), Environmental Protection Agency (EPA) and Pegasus Technologies Corporation, under a National Industrial Competitiveness through Energy, Environment and Economics (NICE) grant program. The system is installed on a 1950s vintage Babcock & Wilcox front-fired (four levels) drum unit with a gross generation capacity of 146 MW The program linked a Unix workstation, where the supervisory control system resides, with a Network 90 Digital Control System (DCS). The system uses a neural network-based nonlinear model of the combustion process to interactively adjust setpoints and bias settings in the DCS. The system performs many {open_quotes}what if{close_quotes} simulations to optimize setpoints for the current operating conditions. The neural network model is updated periodically, learning from the most recent data. New setpoints are generated accordingly and downloaded into the DCS. Setpoint and bias adjustments are constrained within the original control system limits. Conditioning algorithms were developed to handle the inherently {open_quote}noisy{close_quote} input data and to provide stable output recommendations. Test results and parameters used for combustion optimization are summarized in this paper.

  7. Developments and advances in emission control technology. SP-1120

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-12-31

    Automotive emission control is an increasingly complex subject that continues to be of vital importance. Tighter emission standards as well as requirements for increased emission system performance and durability have resulted in ongoing development and continuing advances in emission control technology. A great deal of attention continues to be focused on technologies for emission control during cold-start. Detailed analyses are required to determine fundamental mechanisms which govern emission control under a wide variety of operating conditions. Effects of possible catalyst poisons as well as the mechanical durability of aftertreatment systems are being evaluated. Engine, vehicle, and aftertreatment sensors are being utilized to monitor and ensure emission control performance. Improved analytical techniques are being used to help understand emissions problems and to suggest avenues to solutions. Papers assembled in this volume touch on all of these areas. Catalyst durability papers address issues related to hot vibration testing and catalyst durability based on substrate surface area. A variety of papers related to the chemical composition of fuels address issues such as fuel hydrocarbon and NO conversion in three-way catalysts, fuel composition effects on emissions in urban traffic, and fuel sulfur effects on catalysts and on-board diagnostics (OBD-II) systems. Information useful for understanding the performance of cold-start technologies is described in papers on a numerical method for predicting warm-up characteristics of catalysts systems, axial characterization of warmup and underfloor catalytic converters, and EHC impact on extended soak times. Other approaches for reducing cold-start emissions are addressed in papers on in-cylinder catalysts and the use of intake air oxygen enrichment technology. All papers have been processed separately for inclusion on the database.

  8. Phosphotransferase protein EIIANtr interacts with SpoT, a key enzyme of the stringent response, in Ralstonia eutropha H16.

    Science.gov (United States)

    Karstens, Katja; Zschiedrich, Christopher P; Bowien, Botho; Stülke, Jörg; Görke, Boris

    2014-04-01

    EIIA(Ntr) is a member of a truncated phosphotransferase (PTS) system that serves regulatory functions and exists in many Proteobacteria in addition to the sugar transport PTS. In Escherichia coli, EIIA(Ntr) regulates K(+) homeostasis through interaction with the K(+) transporter TrkA and sensor kinase KdpD. In the β-Proteobacterium Ralstonia eutropha H16, EIIA(Ntr) influences formation of the industrially important bioplastic poly(3-hydroxybutyrate) (PHB). PHB accumulation is controlled by the stringent response and induced under conditions of nitrogen deprivation. Knockout of EIIA(Ntr) increases the PHB content. In contrast, absence of enzyme I or HPr, which deliver phosphoryl groups to EIIA(Ntr), has the opposite effect. To clarify the role of EIIA(Ntr) in PHB formation, we screened for interacting proteins that co-purify with Strep-tagged EIIA(Ntr) from R. eutropha cells. This approach identified the bifunctional ppGpp synthase/hydrolase SpoT1, a key enzyme of the stringent response. Two-hybrid and far-Western analyses confirmed the interaction and indicated that only non-phosphorylated EIIA(Ntr) interacts with SpoT1. Interestingly, this interaction does not occur between the corresponding proteins of E. coli. Vice versa, interaction of EIIA(Ntr) with KdpD appears to be absent in R. eutropha, although R. eutropha EIIA(Ntr) can perfectly substitute its homologue in E. coli in regulation of KdpD activity. Thus, interaction with KdpD might be an evolutionary 'ancient' task of EIIA(Ntr) that was subsequently replaced by interaction with SpoT1 in R. eutropha. In conclusion, EIIA(Ntr) might integrate information about nutritional status, as reflected by its phosphorylation state, into the stringent response, thereby controlling cellular PHB content in R. eutropha.

  9. Second Generation Advanced Reburning for High Efficiency N0x Control

    Energy Technology Data Exchange (ETDEWEB)

    Zamansky, Vladimir M.; Maly, Peter, M.; Sheldon, Mark; Seeker, W. Randall; Folsom, Blair A.

    1997-12-31

    Energy and Environmental Research Corporation is developing a family of high efficiency and low cost NO{sub x} control technologies for coal fired utility boilers based on Advanced Reburning (AR), a synergistic integration of basic reburning with injection of an N-agent. In conventional AR, injection of the reburn fuel is followed by simultaneous N-agent and overfire air injection. The second generation AR systems incorporate several components which can be used in different combinations. These components include: (1) Reburning Injection of the reburn fuel and overfire air. (2) N-agent Injection The N-agent (ammonia or urea) can be injected at different locations: into the reburning zone, along with the overfire air, and downstream of the overfire air injection. (3) N-agent Promotion Several sodium compounds can considerably enhance the NO{sub x} control from N-agent injection. These ''promoters'' can be added to aqueous N-agents. (4) Two Stages of N-agent Injection and Promotion Two N-agents with or without promoters can be injected at different locations for deeper NO{sub x} control. AR systems are intended for post-RACT applications in ozone non-attainment areas where NO{sub x} control in excess of 80% is required. AR will provide flexible installations that allow NO{sub x} levels to be lowered when regulations become more stringent. The total cost of NO{sub x} control for AR systems is approximately half of that for SCR. Experimental and kinetic modeling results for development of these novel AR systems are presented. Tests have been conducted in a 1.0 MMBtu/hr Boiler Simulator Facility with coal as the main fuel and natural gas as the reburning fuel. The results show that high efficiency NO{sub x} control, in the range 84-95%, can be achieved with various elements of AR. A comparative byproduct emission study was performed to compare the emissions from different variants of AR with commercial technologies (reburning and SNCR). For each

  10. Second Generation Advanced Reburning for High Efficiency NOx Control

    Energy Technology Data Exchange (ETDEWEB)

    Vladimir M. Zamansky; Peter M. Maly; Vitali V. Lissianski; Mark S. Sheldon; David Moyeda; Roy Payne

    2001-06-30

    This project develops a family of novel Second Generation Advanced Reburning (SGAR) NO{sub x} control technologies, which can achieve 95% NO{sub x} control in coal fired boilers at a significantly lower cost than Selective Catalytic Reduction (SCR). The conventional Advanced Reburning (AR) process integrates basic reburning and N-agent injection. The SGAR systems include six AR variants: (1) AR-Lean--injection of the N-agent and promoter along with overfire air; (2) AR-Rich--injection of N-agent and promoter into the reburning zone; (3) Multiple Injection Advanced Reburning (MIAR)--injection of N-agents and promoters both into the reburning zone and with overfire air; (4) AR-Lean + Promoted SNCR--injection of N-agents and promoters with overfire air and into the temperature zone at which Selective Non-Catalytic Reduction (SNCR) is effective; (5) AR-Rich + Promoted SNCR--injection of N-agents and promoters into the reburning zone and into the SNCR zone; and (6) Promoted Reburning + Promoted SNCR--basic or promoted reburning followed by basic or promoted SNCR process. The project was conducted in two phases over a five-year period. The work included a combination of analytical and experimental studies to confirm the process mechanisms, identify optimum process configurations, and develop a design methodology for full-scale applications. Phase I was conducted from October, 1995 to September, 1997 and included both analytical studies and tests in bench and pilot-scale test rigs. Phase I moved AR technology to Maturity Level III-Major Subsystems. Phase II is conducted over a 45 month period (October, 1997-June, 2001). Phase II included evaluation of alternative promoters, development of alternative reburning fuel and N-Agent jet mixing systems, and scale up. The goal of Phase II was to move the technology to Maturity Level I-Subscale Integrated System. Tests in combustion facility ranging in firing rate from 0.1 x 10{sup 6} to 10 x 10{sup 6} Btu/hr demonstrated the

  11. MERCURY CONTROL WITH THE ADVANCED HYBRID PARTICULATE COLLECTOR

    Energy Technology Data Exchange (ETDEWEB)

    Steven A. Benson; Stanley J. Miller; Charlene R. Crocker; Kevin C. Galbreath; Jason D. Laumb; Jill M. Zola; Ye Zhuang; Michelle R. Olderbak

    2004-08-01

    This project was awarded under U.S. Department of Energy (DOE) National Energy Technology Laboratory (NETL) Program Solicitation DE-PS26-00NT40769 and specifically addresses Technical Topical Area 4-Testing Novel and Less Mature Control Technologies on Actual Flue Gas at the Pilot Scale. The project team includes the Energy & Environmental Research Center (EERC) as the main contractor; W.L. Gore & Associates, Inc., as a technical and financial partner; and the Big Stone Plant operated by Otter Tail Power Company, host for the field-testing portion of the research. Since 1995, DOE has supported development of a new concept in particulate control called the advanced hybrid particulate collector (AHPC). The AHPC has been licensed to W.L. Gore & Associates, Inc., and is now marketed as the Advanced Hybrid{trademark} filter by Gore. The AHPC combines the best features of electrostatic precipitators (ESPs) and baghouses in a unique configuration, providing major synergism between the two collection methods, both in the particulate collection step and in the transfer of dust to the hopper. The AHPC provides ultrahigh collection efficiency, overcoming the problem of excessive fine-particle emissions with conventional ESPs, and it solves the problem of reentrainment and re-collection of dust in conventional baghouses. The AHPC appears to have unique advantages for mercury control over baghouses or ESPs as an excellent gas-solid contactor. The objective of the original 5-task project is to demonstrate 90% total mercury control in the AHPC at a lower cost than current mercury control estimates. The approach includes bench-scale batch testing that ties the new work to previous results and links results with larger-scale pilot testing with real flue gas on a coal-fired combustion system, pilot-scale testing on a coal-fired combustion system with both a pulse-jet baghouse and an AHPC to prove or disprove the research hypotheses, and field demonstration pilot-scale testing at a

  12. Mercury Control With The Advanced Hybrid Particulate Collector

    Energy Technology Data Exchange (ETDEWEB)

    Steven A. Benson; Stanley J. Miller; Charlene R. Crocker; Kevin C. Galbreath; Jason D. Laumb; Jill M. Zola; Ye Zhuang; Michelle R. Olderbak

    2004-03-31

    This project was awarded under U.S. Department of Energy (DOE) National Energy Technology Laboratory (NETL) Program Solicitation DE-PS26-00NT40769 and specifically addresses Technical Topical Area 4 - Testing Novel and Less Mature Control Technologies on Actual Flue Gas at the Pilot Scale. The project team includes the Energy & Environmental Research Center (EERC) as the main contractor; W.L. Gore & Associates, Inc., as a technical and financial partner; and the Big Stone Plant operated by Otter Tail Power Company, host for the field-testing portion of the research. Since 1995, DOE has supported development of a new concept in particulate control called the advanced hybrid particulate collector (AHPC). The AHPC has been licensed to W.L. Gore and Associates, Inc., and is now marketed as the Advanced Hybrid{trademark} filter by Gore. The AHPC combines the best features of electrostatic precipitators (ESPs) and baghouses in a unique configuration, providing major synergism between the two collection methods, both in the particulate collection step and in the transfer of dust to the hopper. The AHPC provides ultrahigh collection efficiency, overcoming the problem of excessive fine-particle emissions with conventional ESPs, and it solves the problem of reentrainment and re-collection of dust in conventional baghouses. The AHPC appears to have unique advantages for mercury control over baghouses or ESPs as an excellent gas-solid contactor. The objective of the original 5-task project is to demonstrate 90% total mercury control in the AHPC at a lower cost than current mercury control estimates. The approach includes benchscale batch testing that ties the new work to previous results and links results with larger-scale pilot testing with real flue gas on a coal-fired combustion system, pilot-scale testing on a coal fired combustion system with both a pulse-jet baghouse and an AHPC to prove or disprove the research hypotheses, and field demonstration pilot-scale testing at

  13. MERCURY CONTROL WITH THE ADVANCED HYBRID PARTICULATE COLLECTOR

    Energy Technology Data Exchange (ETDEWEB)

    Charlene R. Crocker; Steven A. Benson; Stanley J. Miller

    2003-11-01

    This project was awarded under U.S. Department of Energy (DOE) National Energy Technology Laboratory (NETL) Program Solicitation DE-PS26-00NT40769 and specifically addresses Technical Topical Area 4--Testing Novel and Less Mature Control Technologies on Actual Flue Gas at the Pilot Scale. The project team includes the Energy & Environmental Research Center (EERC) as the main contractor; W.L. Gore & Associates, Inc., as a technical and financial partner; and the Big Stone Plant operated by Otter Tail Power Company, host for the field-testing portion of the research. Since 1995, DOE has supported development of a new concept in particulate control called the advanced hybrid particulate collector (AHPC). The AHPC has been licensed to W.L. Gore & Associates, Inc., and is now marketed as the Advanced Hybrid{trademark} filter by Gore. The AHPC combines the best features of electrostatic precipitators (ESPs) and baghouses in a unique configuration, providing major synergism between the two collection methods, both in the particulate collection step and in the transfer of dust to the hopper. The AHPC provides ultra-high collection efficiency, overcoming the problem of excessive fine-particle emissions with conventional ESPs, and it solves the problem of reentrainment and re-collection of dust in conventional baghouses. The AHPC appears to have unique advantages for mercury control over baghouses or ESPs as an excellent gas-solid contactor. The objective of the original 5-task project is to demonstrate 90% total mercury control in the AHPC at a lower cost than current mercury control estimates. The approach includes bench-scale batch testing that ties the new work to previous results and links results with larger-scale pilot testing with real flue gas on a coal-fired combustion system, pilot-scale testing on a coal-fired combustion system with both a pulse-jet baghouse and an AHPC to prove or disprove the research hypotheses, and field demonstration pilot-scale testing at a

  14. Mercury Control With The Advanced Hybrid Particulate Collector

    Energy Technology Data Exchange (ETDEWEB)

    Steven A. Benson; Stanley J. Miller; Charlene R. Crocker; Kevin C. Galbreath; Jason D. Laumb; Jill M. Zola; Ye Zhuang; Michelle R. Olderbak

    2003-12-31

    This project was awarded under U.S. Department of Energy (DOE) National Energy Technology Laboratory (NETL) Program Solicitation DE-PS26-00NT40769 and specifically addresses Technical Topical Area 4 - Testing Novel and Less Mature Control Technologies on Actual Flue Gas at the Pilot Scale. The project team includes the Energy & Environmental Research Center (EERC) as the main contractor; W.L. Gore & Associates, Inc., as a technical and financial partner; and the Big Stone Plant operated by Otter Tail Power Company, host for the field-testing portion of the research. Since 1995, DOE has supported development of a new concept in particulate control called the advanced hybrid particulate collector (AHPC). The AHPC has been licensed to W.L. Gore and Associates, Inc., and is now marketed as the Advanced Hybrid{trademark} filter by Gore. The AHPC combines the best features of electrostatic precipitators (ESPs) and baghouses in a unique configuration, providing major synergism between the two collection methods, both in the particulate collection step and in the transfer of dust to the hopper. The AHPC provides ultrahigh collection efficiency, overcoming the problem of excessive fine-particle emissions with conventional ESPs, and it solves the problem of reentrainment and re-collection of dust in conventional baghouses. The AHPC appears to have unique advantages for mercury control over baghouses or ESPs as an excellent gas-solid contactor. The objective of the original 5-task project is to demonstrate 90% total mercury control in the AHPC at a lower cost than current mercury control estimates. The approach includes benchscale batch testing that ties the new work to previous results and links results with larger-scale pilot testing with real flue gas on a coal-fired combustion system, pilot-scale testing on a coal fired combustion system with both a pulse-jet baghouse and an AHPC to prove or disprove the research hypotheses, and field demonstration pilot-scale testing at

  15. Advanced illumination control algorithm for medical endoscopy applications

    Science.gov (United States)

    Sousa, Ricardo M.; Wäny, Martin; Santos, Pedro; Morgado-Dias, F.

    2015-05-01

    CMOS image sensor manufacturer, AWAIBA, is providing the world's smallest digital camera modules to the world market for minimally invasive surgery and one time use endoscopic equipment. Based on the world's smallest digital camera head and the evaluation board provided to it, the aim of this paper is to demonstrate an advanced fast response dynamic control algorithm of the illumination LED source coupled to the camera head, over the LED drivers embedded on the evaluation board. Cost efficient and small size endoscopic camera modules nowadays embed minimal size image sensors capable of not only adjusting gain and exposure time but also LED illumination with adjustable illumination power. The LED illumination power has to be dynamically adjusted while navigating the endoscope over changing illumination conditions of several orders of magnitude within fractions of the second to guarantee a smooth viewing experience. The algorithm is centered on the pixel analysis of selected ROIs enabling it to dynamically adjust the illumination intensity based on the measured pixel saturation level. The control core was developed in VHDL and tested in a laboratory environment over changing light conditions. The obtained results show that it is capable of achieving correction speeds under 1 s while maintaining a static error below 3% relative to the total number of pixels on the image. The result of this work will allow the integration of millimeter sized high brightness LED sources on minimal form factor cameras enabling its use in endoscopic surgical robotic or micro invasive surgery.

  16. Advanced Branching Control and Characterization of Inorganic Semiconducting Nanocrystals

    Energy Technology Data Exchange (ETDEWEB)

    Hughes, Steven Michael [Univ. of California, Berkeley, CA (United States)

    2007-01-01

    The ability to finely tune the size and shape of inorganic semiconducting nanocrystals is an area of great interest, as the more control one has, the more applications will be possible for their use. The first two basic shapes develped in nanocrystals were the sphere and the anistropic nanorod. the II_VI materials being used such as Cadmium Selenide (CdSe) and Cadmium Telluride (CdTe), exhibit polytypism, which allows them to form in either the hexagonally packed wurtzite or cubically packed zinc blende crystalline phase. The nanorods are wurtzite with the length of the rod growing along the c-axis. As this grows, stacking faults may form, which are layers of zinc blende in the otherwise wurtzite crystal. Using this polytypism, though, the first generation of branched crystals were developed in the form of the CdTe tetrapod. This is a nanocrystal that nucleates in the zincblend form, creating a tetrahedral core, on which four wurtzite arms are grown. This structure opened up the possibility of even more complex shapes and applications. This disseration investigates the advancement of branching control and further understanding the materials polytypism in the form of the stacking faults in nanorods.

  17. Low-level predation by lytic phage phiIPLA-RODI promotes biofilm formation and triggers the stringent response in Staphylococcus aureus

    Science.gov (United States)

    Fernández, Lucía; González, Silvia; Campelo, Ana Belén; Martínez, Beatriz; Rodríguez, Ana; García, Pilar

    2017-01-01

    An important lesson from the war on pathogenic bacteria has been the need to understand the physiological responses and evolution of natural microbial communities. Bacterial populations in the environment are generally forming biofilms subject to some level of phage predation. These multicellular communities are notoriously resistant to antimicrobials and, consequently, very difficult to eradicate. This has sparked the search for new therapeutic alternatives, including phage therapy. This study demonstrates that S. aureus biofilms formed in the presence of a non-lethal dose of phage phiIPLA-RODI exhibit a unique physiological state that could potentially benefit both the host and the predator. Thus, biofilms formed under phage pressure are thicker and have a greater DNA content. Also, the virus-infected biofilm displayed major transcriptional differences compared to an untreated control. Significantly, RNA-seq data revealed activation of the stringent response, which could slow down the advance of the bacteriophage within the biofilm. The end result would be an equilibrium that would help bacterial cells to withstand environmental challenges, while maintaining a reservoir of sensitive bacterial cells available to the phage upon reactivation of the dormant carrier population. PMID:28102347

  18. Advanced modelling, monitoring, and process control of bioconversion systems

    Science.gov (United States)

    Schmitt, Elliott C.

    Production of fuels and chemicals from lignocellulosic biomass is an increasingly important area of research and industrialization throughout the world. In order to be competitive with fossil-based fuels and chemicals, maintaining cost-effectiveness is critical. Advanced process control (APC) and optimization methods could significantly reduce operating costs in the biorefining industry. Two reasons APC has previously proven challenging to implement for bioprocesses include: lack of suitable online sensor technology of key system components, and strongly nonlinear first principal models required to predict bioconversion behavior. To overcome these challenges batch fermentations with the acetogen Moorella thermoacetica were monitored with Raman spectroscopy for the conversion of real lignocellulosic hydrolysates and a kinetic model for the conversion of synthetic sugars was developed. Raman spectroscopy was shown to be effective in monitoring the fermentation of sugarcane bagasse and sugarcane straw hydrolysate, where univariate models predicted acetate concentrations with a root mean square error of prediction (RMSEP) of 1.9 and 1.0 g L-1 for bagasse and straw, respectively. Multivariate partial least squares (PLS) models were employed to predict acetate, xylose, glucose, and total sugar concentrations for both hydrolysate fermentations. The PLS models were more robust than univariate models, and yielded a percent error of approximately 5% for both sugarcane bagasse and sugarcane straw. In addition, a screening technique was discussed for improving Raman spectra of hydrolysate samples prior to collecting fermentation data. Furthermore, a mechanistic model was developed to predict batch fermentation of synthetic glucose, xylose, and a mixture of the two sugars to acetate. The models accurately described the bioconversion process with an RMSEP of approximately 1 g L-1 for each model and provided insights into how kinetic parameters changed during dual substrate

  19. Advanced h∞ control towards nonsmooth theory and applications

    CERN Document Server

    Orlov, Yury V

    2014-01-01

    This compact monograph is focused on disturbance attenuation in nonsmooth dynamic systems, developing an H∞ approach in the nonsmooth setting. Similar to the standard nonlinear H∞ approach, the proposed nonsmooth design guarantees both the internal asymptotic stability of a nominal closed-loop system and the dissipativity inequality, which states that the size of an error signal is uniformly bounded with respect to the worst-case size of an external disturbance signal. This guarantee is achieved by constructing an energy or storage function that satisfies the dissipativity inequality and is then utilized as a Lyapunov function to ensure the internal stability requirements.    Advanced H∞ Control is unique in the literature for its treatment of disturbance attenuation in nonsmooth systems. It synthesizes various tools, including Hamilton–Jacobi–Isaacs partial differential inequalities as well as Linear Matrix Inequalities. Along with the finite-dimensional treatment, the synthesis is exten...

  20. Coal surface control for advanced fine coal flotation

    Energy Technology Data Exchange (ETDEWEB)

    Fuerstenau, D.W.; Sastry, K.V.S.; Hanson, J.S.; Harris, G.; Sotillo, F.; Diao, J. (California Univ., Berkeley, CA (USA)); Somasundaran, P.; Harris, C.C.; Vasudevan, T.; Liu, D.; Li, C. (Columbia Univ., New York, NY (USA)); Hu, Weibai; Zou, Y.; Chen, W. (Utah Univ., Salt Lake City, UT (USA)); Choudhry, V.; Sehgal, R.; Ghosh, A. (Praxis Engineers, Inc., Milpitas, CA (USA))

    1990-08-15

    The primary objective of this research project is to develop advanced flotation methods for coal cleaning in order to achieve near total pyritic-sulfur removal at 90% Btu recovery, using coal samples procured from six major US coal seams. Concomitantly, the ash content of these coals is to be reduced to 6% or less. Work this quarter concentrated on the following: washability studies, which included particle size distribution of the washability samples, and chemical analysis of washability test samples; characterization studies of induction time measurements, correlation between yield, combustible-material recovery (CMR), and heating-value recovery (HVR), and QA/QC for standard flotation tests and coal analyses; surface modification and control including testing of surface-modifying reagents, restoration of hydrophobicity to lab-oxidized coals, pH effects on coal flotation, and depression of pyritic sulfur in which pyrite depression with calcium cyanide and pyrite depression with xanthated reagents was investigated; flotation optimization and circuitry included staged reagent addition, cleaning and scavenging, and scavenging and middling recycling. Weathering studies are also discussed. 19 figs., 28 tabs.

  1. Advanced Catalytic Converter in Gasoline Enginer Emission Control: A Review

    Directory of Open Access Journals (Sweden)

    Leman A.M.

    2017-01-01

    Full Text Available Exhaust emission from automobile source has become a major contributor to the air pollution and environmental problem. Catalytic converter is found to be one of the most effective tools to reduce the overwhelming exhaust pollutants in our environment. The development of sustainable catalytic converter still remains a critical issue due to the stringent exhaust emission regulations. Another issue such as price and availability of the precious metal were also forced the automotive industry to investigate the alternatives for producing a better replacement for the material used in catalytic converter. This paper aims at reviewing the present development and improvement on the catalytic converter used on the reduction of exhaust emission in order to meet the regulations and market demand. The use of new catalyst such as to replace the noble metal material of Platinum (Pt, Palladium (Pd and Rhodium (Rh has been reviewed. Material such as zeolite, nickel oxide and metal oxide has been found to effectively reduce the emission than the commercial converter. The preparation method of the catalyst has also evolved through the years as it is to ensure a good characteristic of a good monolith catalyst. Ultrasonic treatment with combination of electroplating technique, citrate method and Plasma Electrolytic Oxidation (PEO has been found as the latest novel preparation method on producing an effective catalyst in reducing the exhaust emission.

  2. 3. IFAC workshop: advances in automotive control. Vol. 1. Preprints

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2001-07-01

    As the subject indicates, the aim of this workshop will be to discuss the latest advances related to motor vehicles, but also, and more generally, to exchange ideas between academic partners, car-manufacturers and subcontractors. The programme shows that a special effort has been made in this respect. No doubt plenary lectures are of great importance and the thematic sessions in the different sectors are the essence of such workshops; however, the discussions between experts in the different fields, the meetings between people from industry, universities and public or private laboratories, as well as the resulting exchange of ideas, are at least as important. Research is often criticized for providing merely theoretical results and for the insufficient number of its applications. But the motor vehicle offers a wide field of applications in which we can validate all techniques, tools and methods. This allows us to be involved in all the areas of fundamental research, in all the different possible approaches from fundamental research to technology transfer, and to observe the actual effects of our results. The increase in road traffic was a major problem of the past XXth century. It is clear that one the challenges of the XXIst century will be improve driving safety and comfort. The different work sessions concerning more control, driveline modelling, vehicle dynamics, electronic architecture, intelligent components, engine control, engine modelling, the modelling of combustion and turbocharging, diagnostics and subsystems. The quality of the papers and the diversity of their origins clearly shows the interest that we all take in this key sector of our research and industry. (orig.)

  3. Advanced Stellar Compass - Adeos II - Interface Control Document

    DEFF Research Database (Denmark)

    Betto, Maurizio; Jørgensen, John Leif; Kilsgaard, Søren;

    This document describes the Advanced Stellar Compass (ASC) and defines the interfaces between the instrument and the ADEOS II satellite. The ASC is a highly advanced and autonomous Stellar Reference Unit designed, developed and produced by the Space Instrumentation Group of the Department...

  4. Emission reductions and urban ozone responses under more stringent US standards

    Science.gov (United States)

    Downey, Nicole; Emery, Chris; Jung, Jaegun; Sakulyanontvittaya, Tanarit; Hebert, Laura; Blewitt, Doug; Yarwood, Greg

    2015-01-01

    We use a photochemical grid model instrumented with the high-order Decoupled Direct Method (HDDM) to evaluate the response of ozone (O3) to reductions in US-wide anthropogenic emissions, and to estimate emission reductions necessary to meet more stringent National Ambient Air Quality Standards (NAAQS) for O3. We simulate hourly O3 response to nationwide reductions in nitrogen oxides (NOx) and volatile organic compound (VOC) emissions throughout 2006 and compare O3 responses in 4 US cities: Los Angeles, Sacramento, St. Louis, and Philadelphia. We compare O3 responses between NOx-rich, O3-inhibited urban core sites and NOx-sensitive, higher O3 suburban sites and analyze projected O3 frequency distributions, which can be used to drive health effect models. We find that 2006 anthropogenic NOx and VOC emissions must be reduced by 60-70% to reach annual 4th highest (H4) maximum daily 8-h (MDA8) O3 of 75 ppb (the current US standard) in Sacramento, St. Louis, and Philadelphia, and by 80-85% to reach an H4 MDA8 of 60 ppb. Los Angeles requires larger emissions reductions and achieves an H4 MDA8 of 75 ppb with 92% reductions and 60 ppb with 97% reductions. As emissions are reduced, hourly and MDA8 frequency distributions tend toward mid-level background distributions. Mid-level O3 exposure is an important driver of O3 health impacts calculated by epidemiological models. A significant fraction (at least 48%) of summertime integrated MDA8 O3 at all sites remains after complete elimination of US anthropogenic NOx and VOC emissions, implying that mid-level O3 exposure due to background will become more important as domestic precursor emissions are controlled.

  5. The rapidly evolving centromere-specific histone has stringent functional requirements in Arabidopsis thaliana.

    Science.gov (United States)

    Ravi, Maruthachalam; Kwong, Pak N; Menorca, Ron M G; Valencia, Joel T; Ramahi, Joseph S; Stewart, Jodi L; Tran, Robert K; Sundaresan, Venkatesan; Comai, Luca; Chan, Simon W-L

    2010-10-01

    Centromeres control chromosome inheritance in eukaryotes, yet their DNA structure and primary sequence are hypervariable. Most animals and plants have megabases of tandem repeats at their centromeres, unlike yeast with unique centromere sequences. Centromere function requires the centromere-specific histone CENH3 (CENP-A in human), which replaces histone H3 in centromeric nucleosomes. CENH3 evolves rapidly, particularly in its N-terminal tail domain. A portion of the CENH3 histone-fold domain, the CENP-A targeting domain (CATD), has been previously shown to confer kinetochore localization and centromere function when swapped into human H3. Furthermore, CENP-A in human cells can be functionally replaced by CENH3 from distantly related organisms including Saccharomyces cerevisiae. We have used cenh3-1 (a null mutant in Arabidopsis thaliana) to replace endogenous CENH3 with GFP-tagged variants. A H3.3 tail domain-CENH3 histone-fold domain chimera rescued viability of cenh3-1, but CENH3's lacking a tail domain were nonfunctional. In contrast to human results, H3 containing the A. thaliana CATD cannot complement cenh3-1. GFP-CENH3 from the sister species A. arenosa functionally replaces A. thaliana CENH3. GFP-CENH3 from the close relative Brassica rapa was targeted to centromeres, but did not complement cenh3-1, indicating that kinetochore localization and centromere function can be uncoupled. We conclude that CENH3 function in A. thaliana, an organism with large tandem repeat centromeres, has stringent requirements for functional complementation in mitosis.

  6. Advance Noise Control Fan II: Test Rig Fan Risk Management Study

    Science.gov (United States)

    Lucero, John

    2013-01-01

    Since 1995 the Advanced Noise Control Fan (ANCF) has significantly contributed to the advancement of the understanding of the physics of fan tonal noise generation. The 9'x15' WT has successfully tested multiple high speed fan designs over the last several decades. This advanced several tone noise reduction concepts to higher TRL and the validation of fan tone noise prediction codes.

  7. Direct binding targets of the stringent response alarmone (p)ppGpp.

    Science.gov (United States)

    Kanjee, Usheer; Ogata, Koji; Houry, Walid A

    2012-09-01

    The Escherichia coli stringent response, mediated by the alarmone ppGpp, is responsible for the reorganization of cellular transcription upon nutritional starvation and other stresses. These transcriptional changes occur mainly as a result of the direct effects of ppGpp and its partner transcription factor DksA on RNA polymerase. An often overlooked feature of the stringent response is the direct targeting of other proteins by ppGpp. Here we review the literature on proteins that are known to bind ppGpp and, based on sequence homology, X-ray crystal structures and in silico docking, we propose new potential protein binding targets for ppGpp. These proteins were found to fall into five main categories: (i) cellular GTPases, (ii) proteins involved in nucleotide metabolism, (iii) proteins involved in lipid metabolism, (iv) general metabolic proteins and (v) PLP-dependent basic aliphatic amino acid decarboxylases. Bioinformatic rationale is provided for expanding the role of ppGpp in regulating the activities of the cellular GTPases. Proteins involved in nucleotide and lipid metabolism and general metabolic proteins provide an interesting set of structurally varied stringent response targets. While the inhibition of some PLP-dependent decarboxylases by ppGpp suggests the existence of cross-talk between the acid stress and stringent response systems.

  8. Power Control Technique for Efficient Call Admission Control in Advanced Wirless Networks

    Directory of Open Access Journals (Sweden)

    Ch. Sreenivasa Rao

    2012-06-01

    Full Text Available In 4G networks, call admission control techniques have been proposed to provide Quality of Service (QoS in a network by restricting the access to network resources. Power control is essential in call admission control in order to provide fair access to all users, improve battery lifetime and system performance. But the existing call admission control algorithms rarely consider the power controlling techniques in the handoff process for different traffic classes. In this paper, we propose to develop a power controlled call admission control scheme for handoff in the advanced wireless networks. The incoming call measures the initial interference on it and then the base station starts transmitting the packets to the new call. The new call is rejected when the interference reaches a threshold value.Whenever an existing call meets the power constraint, the transmit power is decremented based on thetraffic class and incoming call obtains this information by monitoring the interference received on it. Theconvergence of the power control algorithm is checked and the power levels of all incoming calls areadjusted. From our simulation results we prove that this power control technique provides efficienthandoff in the 4G networks by increasing the throughput and reducing the delay of the existing users.

  9. Advanced Sensors and Controls for Building Applications: Market Assessment and Potential R&D Pathways

    Energy Technology Data Exchange (ETDEWEB)

    Brambley, M. R. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Haves, P. [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); McDonald, S. C. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Torcellini, P. [National Renewable Energy Lab. (NREL), Golden, CO (United States); Hansen, D. [U.S. Dept. of Energy, Washington, D.C. (United States); Holmberg, D. R. [National Institute of Science and Technology, Gaithersburg, MD (United States); Roth, K. W. [TIAX, LLC, Cambridge, MA (United States)

    2005-04-01

    This document provides a market assessment of existing building sensors and controls and presents a range of technology pathways (R&D options) for pursuing advanced sensors and building control strategies.

  10. PERFORMANCE STUDIES OF INTEGRATED FUZZY LOGIC CONTROLLER FOR BRUSHLESS DC MOTOR DRIVES USING ADVANCED SIMULATION MODEL

    National Research Council Canada - National Science Library

    C, Subba Rami Reddy; M, Surya Kalavathi

    2011-01-01

    This paper introduces an Integrated fuzzy logic controller (IFLC) for brushless dc (BLDC) motor drives using advanced simulation model and presents a comparative study of performances of PID controller and IFLC...

  11. Dynamic Event Tree advancements and control logic improvements

    Energy Technology Data Exchange (ETDEWEB)

    Alfonsi, Andrea [Idaho National Lab. (INL), Idaho Falls, ID (United States); Rabiti, Cristian [Idaho National Lab. (INL), Idaho Falls, ID (United States); Mandelli, Diego [Idaho National Lab. (INL), Idaho Falls, ID (United States); Sen, Ramazan Sonat [Idaho National Lab. (INL), Idaho Falls, ID (United States); Cogliati, Joshua Joseph [Idaho National Lab. (INL), Idaho Falls, ID (United States)

    2015-09-01

    The RAVEN code has been under development at the Idaho National Laboratory since 2012. Its main goal is to create a multi-purpose platform for the deploying of all the capabilities needed for Probabilistic Risk Assessment, uncertainty quantification, data mining analysis and optimization studies. RAVEN is currently equipped with three different sampling categories: Forward samplers (Monte Carlo, Latin Hyper Cube, Stratified, Grid Sampler, Factorials, etc.), Adaptive Samplers (Limit Surface search, Adaptive Polynomial Chaos, etc.) and Dynamic Event Tree (DET) samplers (Deterministic and Adaptive Dynamic Event Trees). The main subject of this document is to report the activities that have been done in order to: start the migration of the RAVEN/RELAP-7 control logic system into MOOSE, and develop advanced dynamic sampling capabilities based on the Dynamic Event Tree approach. In order to provide to all MOOSE-based applications a control logic capability, in this Fiscal Year an initial migration activity has been initiated, moving the control logic system, designed for RELAP-7 by the RAVEN team, into the MOOSE framework. In this document, a brief explanation of what has been done is going to be reported. The second and most important subject of this report is about the development of a Dynamic Event Tree (DET) sampler named “Hybrid Dynamic Event Tree” (HDET) and its Adaptive variant “Adaptive Hybrid Dynamic Event Tree” (AHDET). As other authors have already reported, among the different types of uncertainties, it is possible to discern two principle types: aleatory and epistemic uncertainties. The classical Dynamic Event Tree is in charge of treating the first class (aleatory) uncertainties; the dependence of the probabilistic risk assessment and analysis on the epistemic uncertainties are treated by an initial Monte Carlo sampling (MCDET). From each Monte Carlo sample, a DET analysis is run (in total, N trees). The Monte Carlo employs a pre-sampling of the

  12. COMPARATIVEANALYSIS OF ADVANCED CONTROLLERS IN A HEAT EXCHANGER

    OpenAIRE

    P. Sivakumar

    2013-01-01

    Temperature control of the shell and tube heat exchanger is characteristics of nonlinear, time varying and time lag. Since the temperature control with conventional PID controller cannot meet a wide range of precision temperature control requirement, we design temperature control system of the shell and tube heat exchanger by combining fuzzy and PID control methods in this paper. The simulation and experiments are carried out; making a comparison with conventional PID control showing that fuz...

  13. Designing and Testing Contols to Mitigate Dynamic Loads in the Controls Advanced Research Turbine: Preprint

    Energy Technology Data Exchange (ETDEWEB)

    Wright, A.D.; Stol, K.A.

    2008-01-01

    The National Renewable Energy Laboratory is designing, implementing, and testing advanced controls to maximize energy extraction and reduce structural dynamic loads of wind turbines. These control designs are based on a linear model of the turbine that is generated by specialized modeling software. In this paper, we show the design and simulation testing of a control algorithm to mitigate blade, tower, and drivetrain loads using advanced state-space control design methods.

  14. High Temperature Supersonic Jet Noise - Fundamental Studies and Control using Advanced Actuation Methods

    Science.gov (United States)

    2016-08-24

    decades, however methods of measurably controlling -reducing jet noise in an efficient and robust manner remain evasive. Previous research has shown...2016 1-May-2013 30-Apr-2016 High Temperature Supersonic Jet Noise - Fundamental Studies and Control using Advanced Actuation Methods The views...and Control using Advanced Actuation Methods Report Title Understanding and controlling jet noise has been the focus of analytical, computational and

  15. NASA's advanced control law program for the F-8 digital fly-by-wire aircraft

    Science.gov (United States)

    Elliott, J. R.

    1977-01-01

    This paper briefly describes the NASA F-8 Digital Fly-By-Wire (DFBW) and Langley Research Center's role in investigating and promoting advanced control laws for possible flight experimentation and also provides a brief description of the Phase II DFBW F-8 aircraft and its control system. Some of the advanced control law study objectives and guidelines are discussed, and some mathematical models which are useful in the control analysis problem are provided.

  16. Physical control oriented model of large scale refrigerators to synthesize advanced control schemes. Design, validation, and first control results

    Science.gov (United States)

    Bonne, François; Alamir, Mazen; Bonnay, Patrick

    2014-01-01

    In this paper, a physical method to obtain control-oriented dynamical models of large scale cryogenic refrigerators is proposed, in order to synthesize model-based advanced control schemes. These schemes aim to replace classical user experience designed approaches usually based on many independent PI controllers. This is particularly useful in the case where cryoplants are submitted to large pulsed thermal loads, expected to take place in the cryogenic cooling systems of future fusion reactors such as the International Thermonuclear Experimental Reactor (ITER) or the Japan Torus-60 Super Advanced Fusion Experiment (JT-60SA). Advanced control schemes lead to a better perturbation immunity and rejection, to offer a safer utilization of cryoplants. The paper gives details on how basic components used in the field of large scale helium refrigeration (especially those present on the 400W @1.8K helium test facility at CEA-Grenoble) are modeled and assembled to obtain the complete dynamic description of controllable subsystems of the refrigerator (controllable subsystems are namely the Joule-Thompson Cycle, the Brayton Cycle, the Liquid Nitrogen Precooling Unit and the Warm Compression Station). The complete 400W @1.8K (in the 400W @4.4K configuration) helium test facility model is then validated against experimental data and the optimal control of both the Joule-Thompson valve and the turbine valve is proposed, to stabilize the plant under highly variable thermals loads. This work is partially supported through the European Fusion Development Agreement (EFDA) Goal Oriented Training Program, task agreement WP10-GOT-GIRO.

  17. MultiController: the PLC-SCADA object for advanced regulation

    CERN Document Server

    Ortola, J

    2007-01-01

    Nowadays, industrial solutions with PLCs (Programmable Logic Controllers) have basic control loop features. The SCADA (Supervisory Control And Data Acquisition) system is a key point of the process control system due to an efficient HMI (Human Machine Interfaces) that provides an open method of tuning and leading possibilities. As a consequence, advanced control algorithms have to be developed and implemented for those PLC-SCADA solutions in order to provide perspectives in solving complex and critical regulation problems. The MultiController is an object integrated for a large scale project at CERN (the European Organization for Nuclear Research) named LHC-GCS (Large Hadron Collider - Gas Control System). It is developed for a Framework called CERN-UNICOS based on PLC-SCADA facilities. The MultiController object offers various advanced control loop strategies. It gives to the user advanced control algorithms like PID, Smith Predictor, PFC, GPC and RST. It is implemented as a monolithic entity (in PLC and SCA...

  18. Advanced Colloids Experiment (Temperature Controlled) - ACE-T6

    Science.gov (United States)

    Meyer, William V.; Sicker, Ronald J.; Bailey, Kelly; Eustace, John; Lynch, Matthew

    2017-01-01

    Increment 53 - 54 Science Symposium presentation of Advanced Colloids Experiment (ACE-T6) to RPO. The purpose of this event is for Principal Investigators to present their science objectives, testing approach, and measurement methods to agency scientists, managers, and other investigators.

  19. Advanced Colloids Experiment (Temperature Controlled) - ACE-T9

    Science.gov (United States)

    Marr, David W. M.; Meyer, William V.; Sicker, Ronald; Bailey, Kelly; Eustace, John G.

    2017-01-01

    Increment 53 - 54 Science Symposium presentation of Advanced Colloids Experiment (ACE-T9) to RPO. The purpose of this event is for Principal Investigators to present their science objectives, testing approach, and measurement methods to agency scientists, managers, and other investigators.

  20. Field Testing LIDAR Based Feed-Forward Controls on the NREL Controls Advanced Research Turbine: Preprint

    Energy Technology Data Exchange (ETDEWEB)

    Scholbrock, A. K.; Fleming, P. A.; Fingersh, L. J.; Wright, A. D.; Schlipf, D.; Haizmann, F.; Belen, F.

    2013-01-01

    Wind turbines are complex, nonlinear, dynamic systems driven by aerodynamic, gravitational, centrifugal, and gyroscopic forces. The aerodynamics of wind turbines are nonlinear, unsteady, and complex. Turbine rotors are subjected to a chaotic three-dimensional (3-D) turbulent wind inflow field with imbedded coherent vortices that drive fatigue loads and reduce lifetime. In order to reduce cost of energy, future large multimegawatt turbines must be designed with lighter weight structures, using active controls to mitigate fatigue loads, maximize energy capture, and add active damping to maintain stability for these dynamically active structures operating in a complex environment. Researchers at the National Renewable Energy Laboratory (NREL) and University of Stuttgart are designing, implementing, and testing advanced feed-back and feed-forward controls in order to reduce the cost of energy for wind turbines.

  1. Constitutive Stringent Response Restores Viability of Bacillus subtilis Lacking Structural Maintenance of Chromosome Protein.

    Directory of Open Access Journals (Sweden)

    Camille Benoist

    Full Text Available Bacillus subtilis mutants lacking the SMC-ScpAB complex are severely impaired for chromosome condensation and partitioning, DNA repair, and cells are not viable under standard laboratory conditions. We isolated suppressor mutations that restored the capacity of a smc deletion mutant (Δsmc to grow under standard conditions. These suppressor mutations reduced chromosome segregation defects and abrogated hypersensitivity to gyrase inhibitors of Δsmc. Three suppressor mutations were mapped in genes involved in tRNA aminoacylation and maturation pathways. A transcriptomic survey of isolated suppressor mutations pointed to a potential link between suppression of Δsmc and induction of the stringent response. This link was confirmed by (pppGpp quantification which indicated a constitutive induction of the stringent response in multiple suppressor strains. Furthermore, sublethal concentrations of arginine hydroxamate (RHX, a potent inducer of stringent response, restored growth of Δsmc under non permissive conditions. We showed that production of (pppGpp alone was sufficient to suppress the thermosensitivity exhibited by the Δsmc mutant. Our findings shed new light on the coordination between chromosome dynamics mediated by SMC-ScpAB and other cellular processes during rapid bacterial growth.

  2. Multicontroller: an object programming approach to introduce advanced control algorithms for the GCS large scale project

    CERN Document Server

    Cabaret, S; Coppier, H; Rachid, A; Barillère, R; CERN. Geneva. IT Department

    2007-01-01

    The GCS (Gas Control System) project team at CERN uses a Model Driven Approach with a Framework - UNICOS (UNified Industrial COntrol System) - based on PLC (Programming Language Controller) and SCADA (Supervisory Control And Data Acquisition) technologies. The first' UNICOS versions were able to provide a PID (Proportional Integrative Derivative) controller whereas the Gas Systems required more advanced control strategies. The MultiController is a new UNICOS object which provides the following advanced control algorithms: Smith Predictor, PFC (Predictive Function Control), RST* and GPC (Global Predictive Control). Its design is based on a monolithic entity with a global structure definition which is able to capture the desired set of parameters of any specific control algorithm supported by the object. The SCADA system -- PVSS - supervises the MultiController operation. The PVSS interface provides users with supervision faceplate, in particular it links any MultiController with recipes: the GCS experts are ab...

  3. Human factors design review guidelines for advanced nuclear control room technologies

    Energy Technology Data Exchange (ETDEWEB)

    O' Hara, J.; Brown, W. (Brookhaven National Lab., Upton, NY (United States)); Granda, T.; Baker, C. (Carlow Associates, Inc., Fairfax, VA (United States))

    1991-01-01

    Advanced control rooms (ACRs) for future nuclear power plants are being designed utilizing computer-based technologies. The US Nuclear Regulatory Commission reviews the human engineering aspects of such control rooms to ensure that they are designed to good human factors engineering principles and that operator performance and reliability are appropriately supported in order to protect public health and safety. This paper describes the rationale, general approach, and initial development of an NRC Advanced Control Room Design Review Guideline. 20 refs., 1 fig.

  4. Advances in microbial insect control in horticultural ecosystems

    Science.gov (United States)

    The use of microbial organisms as biological control agents has progressed significantly since Metschnikoff launched the first attempt at microbial insect control with Metarhizium anisopliae in 1879. Following the lead of Metschnikoff, entomopathogenic nematodes, fungi, bacteria and viruses have b...

  5. Modeling and Advanced Control for Sustainable Process Systems

    Science.gov (United States)

    This book chapter introduces a novel process systems engineering framework that integrates process control with sustainability assessment tools for the simultaneous evaluation and optimization of process operations. The implemented control strategy consists of a biologically-insp...

  6. Recent Advances in Bidirectional Modeling and Structural Control

    Directory of Open Access Journals (Sweden)

    Satyam Paul

    2016-01-01

    estimation of velocity and position from acceleration signals, and optimal placement of the sensors and control devices. The importance of control devices and its applications to minimize bidirectional vibrations has been illustrated. Finally, the applications of structural control systems in real buildings and their performance have been reviewed.

  7. Algorithm Design and Validation for Adaptive Nonlinear Control Enhancement (ADVANCE) Technology Development for Resilient Flight Control Project

    Data.gov (United States)

    National Aeronautics and Space Administration — SSCI proposes to develop and test a framework referred to as the ADVANCE (Algorithm Design and Validation for Adaptive Nonlinear Control Enhancement), within which...

  8. Recent advances in electrical engineering and control applications

    CERN Document Server

    Bououden, Sofiane; Zelinka, Ivan

    2017-01-01

    This book of proceedings includes papers presenting the state of art in electrical engineering and control theory as well as their applications. The topics focus on classical as well as modern methods for modeling, control, identification and simulation of complex systems with applications in science and engineering. The papers were selected from the hottest topic areas, such as control and systems engineering, renewable energy, faults diagnosis—faults tolerant control, large-scale systems, fractional order systems, unconventional algorithms in control engineering, signals and communications. The control and design of complex systems dynamics, analysis and modeling of its behavior and structure is vitally important in engineering, economics and in science generally science today. Examples of such systems can be seen in the world around us and are a part of our everyday life. Application of modern methods for control, electronics, signal processing and more can be found in our mobile phones, car engines, hom...

  9. Applications of advanced control methods in spacecrafts:progress, challenges, and future prospects

    Institute of Scientific and Technical Information of China (English)

    Yong-chun XIE; Huang HUANG; Yong HU; Guo-qi ZHANG

    2016-01-01

    We aim at examining the current status of advanced control methods in spacecrafts from an engineer’s perspective. Instead of reviewing all the fancy theoretical results in advanced control for aerospace vehicles, the focus is on the advanced control methods that have been practically applied to spacecrafts during flight tests, or have been tested in real time on ground facilities and general testbeds/simulators built with actual flight data. The aim is to provide engineers with all the possible control laws that are readily available rather than those that are tested only in the laboratory at the moment. It turns out that despite the blooming developments of modern control theories, most of them have various limitations, which stop them from being practically applied to spacecrafts. There are a limited number of spacecrafts that are controlled by advanced control methods, among which H2/H∞ robust control is the most popular method to deal with flexible structures, adaptive control is commonly used to deal with model/parameter uncertainty, and the linear quadratic regulator (LQR) is the most frequently used method in case of optimal control. It is hoped that this review paper will enlighten aerospace engineers who hold an open mind about advanced control methods, as well as scholars who are enthusiastic about engineering-oriented problems.

  10. Global gene expression during stringent response in Corynebacterium glutamicum in presence and absence of the rel gene encoding (pppGpp synthase

    Directory of Open Access Journals (Sweden)

    Kalinowski Jörn

    2006-09-01

    Full Text Available Background The stringent response is the initial reaction of microorganisms to nutritional stress. During stringent response the small nucleotides (pppGpp act as global regulators and reprogram bacterial transcription. In this work, the genetic network controlled by the stringent response was characterized in the amino acid-producing Corynebacterium glutamicum. Results The transcriptome of a C. glutamicum rel gene deletion mutant, unable to synthesize (pppGpp and to induce the stringent response, was compared with that of its rel-proficient parent strain by microarray analysis. A total of 357 genes were found to be transcribed differentially in the rel-deficient mutant strain. In a second experiment, the stringent response was induced by addition of DL-serine hydroxamate (SHX in early exponential growth phase. The time point of the maximal effect on transcription was determined by real-time RT-PCR using the histidine and serine biosynthetic genes. Transcription of all of these genes reached a maximum at 10 minutes after SHX addition. Microarray experiments were performed comparing the transcriptomes of SHX-induced cultures of the rel-proficient strain and the rel mutant. The differentially expressed genes were grouped into three classes. Class A comprises genes which are differentially regulated only in the presence of an intact rel gene. This class includes the non-essential sigma factor gene sigB which was upregulated and a large number of genes involved in nitrogen metabolism which were downregulated. Class B comprises genes which were differentially regulated in response to SHX in both strains, independent of the rel gene. A large number of genes encoding ribosomal proteins fall into this class, all being downregulated. Class C comprises genes which were differentially regulated in response to SHX only in the rel mutant. This class includes genes encoding putative stress proteins and global transcriptional regulators that might be

  11. Advances in the control of markov jump linear systems with no mode observation

    CERN Document Server

    Vargas, Alessandro N; do Val, João B R

    2016-01-01

    This brief broadens readers’ understanding of stochastic control by highlighting recent advances in the design of optimal control for Markov jump linear systems (MJLS). It also presents an algorithm that attempts to solve this open stochastic control problem, and provides a real-time application for controlling the speed of direct current motors, illustrating the practical usefulness of MJLS. Particularly, it offers novel insights into the control of systems when the controller does not have access to the Markovian mode.

  12. Advances in analysis and control of timedelayed dynamical systems

    CERN Document Server

    Sun, Jianqiao

    2013-01-01

    Analysis and control of timedelayed systems have been applied in a wide range of applications, ranging from mechanical, control, economic, to biological systems. Over the years, there has been a steady stream of interest in timedelayed dynamic systems, this book takes a snap shot of recent research from the world leading experts in analysis and control of dynamic systems with time delay to provide a bird's eye view of its development. The topics covered in this book include solution methods, stability analysis and control of periodic dynamic systems with time delay, bifurcations, stochastic dy

  13. Advanced Polymer Composite Molding Through Intelligent Process Analysis and Control

    Science.gov (United States)

    2004-11-30

    In this project. process analysis of Resin Transfer Molding (RTM) was carried out and adaptive process control models were developed. In addition, a...aforementioned work in three separate sections: (1) process analysis and adaptive control modeling, (2) manufacturing of non-invasive sensor, end (3) list of publications resulting from this project.

  14. Benchmarking Advanced Control Algorithms for a Laser Scanner System

    DEFF Research Database (Denmark)

    Stoustrup, Jakob; Ordys, A.W.; Smillie, I.

    1996-01-01

    The paper describes tests performed on the laser scanner system toassess feasibility of modern control techniques in achieving a requiredperformance in the trajectory following problem. The two methods tested areQTR H-infinity and Predictive Control. The results are ilustated ona simulation example....

  15. Research advances in control methods of wearable walking assist robots

    Directory of Open Access Journals (Sweden)

    Xia ZHANG

    2016-04-01

    Full Text Available As the proportion of the elderly in China increases, the need for robotic assist walking is growing. The assisted-as-needed (AAN property of a wearable walking assist robot matches a user’s biological need and improves the flexibility, appetency and friendliness of a mechanical system. To realize AAN walking and aiming at realizing master/slave flexible assist, a new hybrid control method consisting of hip joint control based on central pattern generators and knee joint impedance structured control is proposed. The adaptation of a robot's master/slave motion mode to a user's physical function, the continuous switching method for knee joint impedance structured control and its stability, and the AAN effect of the Hybrid control theory are studied, which provides a new thought for the development of wearable walking assist robots.

  16. Guest Editorial Advanced Distributed Control of Energy Conversion Devices and Systems

    DEFF Research Database (Denmark)

    Davoudi, Ali; Guerrero, Josep M.; Lewis, Frank;

    2014-01-01

    The papers in this special issue on advanced distributed control of energy conversion devices and systems are loosely grouped into three categories: 1) ac energy conversion systems; 2) dc energy conversion systems; and 3) optimization and standards....

  17. Realization of Low Power High-Speed Channel Filters with Stringent Adjacent Channel Attenuation Specifications for Wireless Communication Receivers

    Science.gov (United States)

    Mathew, Jimson; Mahesh, R.; Vinod, A. P.; Lai, Edmund M.-K.

    Finite impulse response (FIR) filtering is the most computationally intensive operation in the channelizer of a wireless communication receiver. Higher order FIR channel filters are needed in the channelizer to meet the stringent adjacent channel attenuation specifications of wireless communications standards. The computational cost of FIR filters is dominated by the complexity of the coefficient multipliers. Even though many methods for reducing the complexity of filter multipliers have been proposed in literature, these works focused on lower order filters. This paper presents a coefficient-partitioning-based binary subexpression elimination method for realizing low power FIR filters. We show that the FIR filters implemented using proposed method consume less power and achieve speed improvement compared to existing filter implementations. Design examples of the channel filters employed in the Digital Advanced Mobile Phone System (D-AMPS) and Personal Digital Cellular (PDC) receivers show that the proposed method achieved 23% average reductions of full adder and power consumption and 23.3% reduction of delay over the best existing method. Synthesis results show that the proposed method offers average area reduction of 8% and power reduction of 22% over the best known method in literature.

  18. Microgrid Controller and Advanced Distribution Management System Survey Report

    Energy Technology Data Exchange (ETDEWEB)

    Liu, Guodong [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Starke, Michael R. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Herron, Andrew N. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States)

    2016-07-01

    A microgrid controller, which serves as the heart of a microgrid, is responsible for optimally managing the distributed energy resources, energy storage systems, and responsive demand and for ensuring the microgrid is being operated in an efficient, reliable, and resilient way. As the market for microgrids has blossomed in recently years, many vendors have released their own microgrid controllers to meet the various needs of different microgrid clients. However, due to the absence of a recognized standard for such controllers, vendor-supported microgrid controllers have a range of functionalities that are significantly different from each other in many respects. As a result the current state of the industry has been difficult to assess. To remedy this situation the authors conducted a survey of the functions of microgrid controllers developed by vendors and national laboratories. This report presents a clear indication of the state of the microgrid-controller industry based on analysis of the survey results. The results demonstrate that US Department of Energy funded research in microgrid controllers is unique and not competing with that of industry.

  19. Advances in automation and control research in China

    Institute of Scientific and Technical Information of China (English)

    CHENG DaiZhan

    2009-01-01

    Automation is the utilization of control techniques together with other Information technology to control industrial processes,reducing the need for human intervention.It plays a highly important role in social and economy as well as In daily life.Control theory is the theory of automation,and is an interdisciplinary branch of engineering and mathematics,examining the behavior of dynamical systems.China has a long history of manufacturing automatic devices.In recent years,some rapid progresses in control theory have been made in China.Many new theories and new methodologies have been developed to meet the increasing demands in industry,agriculture,defense,and other social sectors.Contemporary sciences such as complexity,systems biology,quantum technologies,have also found their close links to control theories and technologies.On the other hand,control theory itself has many unsolved fundamental problems requiring further studies and investigation.This paper is to review the development and progress that have been made in all these aspects in China.Some remarks on the future development of control theory are also presented.

  20. Neural networks for advanced control of robot manipulators.

    Science.gov (United States)

    Patino, H D; Carelli, R; Kuchen, B R

    2002-01-01

    Presents an approach and a systematic design methodology to adaptive motion control based on neural networks (NNs) for high-performance robot manipulators, for which stability conditions and performance evaluation are given. The neurocontroller includes a linear combination of a set of off-line trained NNs, and an update law of the linear combination coefficients to adjust robot dynamics and payload uncertain parameters. A procedure is presented to select the learning conditions for each NN in the bank. The proposed scheme, based on fixed NNs, is computationally more efficient than the case of using the learning capabilities of the neural network to be adapted, as that used in feedback architectures that need to propagate back control errors through the model to adjust the neurocontroller. A practical stability result for the neurocontrol system is given. That is, we prove that the control error converges asymptotically to a neighborhood of zero, whose size is evaluated and depends on the approximation error of the NN bank and the design parameters of the controller. In addition, a robust adaptive controller to NN learning errors is proposed, using a sign or saturation switching function in the control law, which leads to global asymptotic stability and zero convergence of control errors. Simulation results showing the practical feasibility and performance of the proposed approach to robotics are given.

  1. An Advanced Rapid Cycling CO2 and H2O Control System for PLSS Project

    Data.gov (United States)

    National Aeronautics and Space Administration — NASA's planned future missions set stringent demands on the design of the Portable Life Support Systems (PLSS), requiring dramatic reductions in weight, decreased...

  2. An Advanced Rapid Cycling CO2 and H2O Control System for PLSS Project

    Data.gov (United States)

    National Aeronautics and Space Administration — NASA's planned future missions set stringent demands on the design of the Portable Life Support Systems (PLSS) used to cool the astronaut and provide them with air....

  3. Advanced Electric Distribution, Switching, and Conversion Technology for Power Control

    Science.gov (United States)

    Soltis, James V.

    1998-01-01

    The Electrical Power Control Unit currently under development by Sundstrand Aerospace for use on the Fluids Combustion Facility of the International Space Station is the precursor of modular power distribution and conversion concepts for future spacecraft and aircraft applications. This unit combines modular current-limiting flexible remote power controllers and paralleled power converters into one package. Each unit includes three 1-kW, current-limiting power converter modules designed for a variable-ratio load sharing capability. The flexible remote power controllers can be used in parallel to match load requirements and can be programmed for an initial ON or OFF state on powerup. The unit contains an integral cold plate. The modularity and hybridization of the Electrical Power Control Unit sets the course for future spacecraft electrical power systems, both large and small. In such systems, the basic hybridized converter and flexible remote power controller building blocks could be configured to match power distribution and conversion capabilities to load requirements. In addition, the flexible remote power controllers could be configured in assemblies to feed multiple individual loads and could be used in parallel to meet the specific current requirements of each of those loads. Ultimately, the Electrical Power Control Unit design concept could evolve to a common switch module hybrid, or family of hybrids, for both converter and switchgear applications. By assembling hybrids of a common current rating and voltage class in parallel, researchers could readily adapt these units for multiple applications. The Electrical Power Control Unit concept has the potential to be scaled to larger and smaller ratings for both small and large spacecraft and for aircraft where high-power density, remote power controllers or power converters are required and a common replacement part is desired for multiples of a base current rating.

  4. Advances in control system technology for aerospace applications

    CERN Document Server

    2016-01-01

    This book is devoted to Control System Technology applied to aerospace and covers the four disciplines Cognitive Engineering, Computer Science, Operations Research, and Servo-Mechanisms. This edited book follows a workshop held at the Georgia Institute of Technology in June 2012, where the today's most important aerospace challenges, including aerospace autonomy, safety-critical embedded software engineering, and modern air transportation were discussed over the course of two days of intense interactions among leading aerospace engineers and scientists. Its content provide a snapshot of today's aerospace control research and its future, including Autonomy in space applications, Control in space applications, Autonomy in aeronautical applications, Air transportation, and Safety-critical software engineering.

  5. Advanced WEC Dynamics & Controls FY16 Testing Report

    Energy Technology Data Exchange (ETDEWEB)

    Coe, Ryan Geoffrey [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Bacelli, Giorgio [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Wilson, David G. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Patterson, David Charles [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

    2016-10-01

    A model-scale wave tank test was conducted in the interest of improving control systems design of wave energy converters (WECs). The success of most control strategies is based directly upon the availability of a reduced-order model with the ability to capture the dynamics of the system with sufficient accuracy. For this reason, the test described in this report, which is the first in a series of planned tests on WEC controls, focused on system identification (system ID) and model validation.

  6. 77 FR 53199 - California State Motor Vehicle Pollution Control Standards; Advanced Clean Car Program; Request...

    Science.gov (United States)

    2012-08-31

    ... AGENCY California State Motor Vehicle Pollution Control Standards; Advanced Clean Car Program; Request... control of emissions from new motor vehicles or new motor vehicle engines subject to this part. No state... crankcase emission standards) for the control of emissions from new motor vehicles or new motor vehicle...

  7. Application of CyboCon Advanced Adjustment and Control Software Package in Delayed Coking Unit

    Institute of Scientific and Technical Information of China (English)

    Guo Hua

    2002-01-01

    This article refers to application of the CyboCon software package based upon the model-free adaptive control (MFA) in the 800-kt/a delayed coking unit to realize an advanced adjustment and control strategy for the temperature control of the heater. Operation tests have revealed the convenience in operating system and simplicity in maintenance, leading to good economic benefits.

  8. A stringent test of μ − e universality in $K\\to l\

    CERN Document Server

    Winhart, Andreas

    2009-01-01

    New interest has arisen in measuring the ratio $R_K$ = $K_{e}2/K_{/mu}2$, as recent high-intensity kaon experiments arc able to largely improve the precision. With ~150000 collected Ke2 decays, the NA62 experiment has increased the world $K_{e}2$ sample by an order of magnitude, allowing a stringent test of $\\mu - e$ lepton universality. Here, we describe the experiment and summarize the status of the analysis based on ~40 % of the total data sample taken in 2007.

  9. A mini-IRES sequence for stringent selection of high producers

    Indian Academy of Sciences (India)

    Jun Yan; Hailin Yang; Guohua Yue; Wenda Gao

    2013-06-01

    Internal Ribosome Entry Site (IRES) sequences have been widely used to link the expression of two independent proteins on the same mRNA transcript. Genes encoding fluorescent proteins or drug-resistance enzymes are usually placed downstream of IRES, serving as expression indicators or selection markers. In biological applications where the upstream gene-of-interest is to be expressed at extremely high levels, it is often desirable to purposely reduce IRES downstream gene expression to economize the cellular resources and/or to generate more stringent selection pressure. Here we describe a miniature IRES mutant sequence (IRESmut3) with dramatically diminished co-translational efficiency to fulfill these purposes.

  10. A Novel Percutaneous Electrode Implant for Improving Robustness in Advanced Myoelectric Control

    OpenAIRE

    2016-01-01

    Despite several decades of research, electrically powered hand and arm prostheses are still controlled with very simple algorithms that process the surface electromyogram (EMG) of remnant muscles to achieve control of one prosthetic function at a time. More advanced machine learning methods have shown promising results under laboratory conditions. However, limited robustness has largely prevented the transfer of these laboratory advances to clinical applications. In this paper, we introduce a...

  11. Economic Benefits of Advanced Control Strategies in Biological Nutrient Removal Systems

    DEFF Research Database (Denmark)

    Carstensen, J.; Nielsen, M.K.; Harremoës, Poul

    1994-01-01

    Advances in on-line monitoring of nutrient salt concentrations and computer technology has created a large potential for the implementation of advanced and complex control strategies in biological nutrient removal systems. The majority of wastewater treatment plants today are operated with very......, and that the complexity in reactor design of biological nutrient removal systems will be substituted by complexity in control in the future....

  12. Advanced Control System Design for Hypersonic Vehicles Project

    Data.gov (United States)

    National Aeronautics and Space Administration — Guidance and control system design for hypersonic vehicles is more challenging than their subsonic and supersonic counterparts. Some of these challenges are (i)...

  13. Advanced Stellar Compass, Electrical Interface Control Document for Grace

    DEFF Research Database (Denmark)

    Madsen, Peter Buch; Jørgensen, Finn E; Jørgensen, John Leif;

    1999-01-01

    The Space Instrumentation Group has made an Electrical Interface Control Document for the GRACE (Gravity Recovery and Climate Experiment Mission) satellite, witch describes the electrical interface between the Star Imager and the Computer (IPU) on the GRACE Satellite....

  14. Advances in sliding mode control concept, theory and implementation

    CERN Document Server

    Janardhanan, S; Spurgeon, Sarah

    2013-01-01

    The sliding mode control paradigm has become a mature technique for the design of robust controllers for a wide class of systems including nonlinear, uncertain and time-delayed systems. This book is a collection of plenary and invited talks delivered at the 12th IEEE International Workshop on Variable Structure System held at the Indian Institute of Technology, Mumbai, India in January 2012. After the workshop, these researchers were invited to develop book chapters for this edited collection in order to reflect the latest results and open research questions in the area. The contributed chapters have been organized by the editors to reflect the various themes of sliding mode control which are the current areas of theoretical research and applications focus; namely articulation of the fundamental underpinning theory of the sliding mode design paradigm, sliding modes for decentralized system representations, control of time-delay systems, the higher order sliding mode concept, results applicable to nonlinear an...

  15. Advanced nonlinear control of three phase series active power filter

    Directory of Open Access Journals (Sweden)

    Abouelmahjoub Y.

    2014-01-01

    Full Text Available The problem of controlling three-phase series active power filter (TPSAPF is addressed in this paper in presence of the perturbations in the voltages of the electrical supply network. The control objective of the TPSAPF is twofold: (i compensation of all voltage perturbations (voltage harmonics, voltage unbalance and voltage sags, (ii regulation of the DC bus voltage of the inverter. A controller formed by two nonlinear regulators is designed, using the Backstepping technique, to provide the above compensation. The regulation of the DC bus voltage of the inverter is ensured by the use of a diode bridge rectifier which its output is in parallel with the DC bus capacitor. The Analysis of controller performances is illustrated by numerical simulation in Matlab/Simulink environment.

  16. Morphing Flight Control Surface for Advanced Flight Performance Project

    Data.gov (United States)

    National Aeronautics and Space Administration — In this SBIR project, a new Morphing Flight Control Surface (MFCS) will be developed. The distinction of the research effort is that the SenAnTech team will employ...

  17. Advanced Instrumentation, Information, and Control Systems Technologies Technical Program Plan

    Energy Technology Data Exchange (ETDEWEB)

    Bruce Hallbert

    2012-09-01

    Reliable instrumentation, information, and control (II&C) systems technologies are essential to ensuring safe and efficient operation of the U.S. light water reactor (LWR) fleet. These technologies affect every aspect of nuclear power plant (NPP) and balance-of-plant operations. In 1997, the National Research Council conducted a study concerning the challenges involved in modernization of digital instrumentation and control systems in NPPs. Their findings identified the need for new II&C technology integration.

  18. SCHEME (Soft Control Human error Evaluation MEthod) for advanced MCR HRA

    Energy Technology Data Exchange (ETDEWEB)

    Jang, Inseok; Jung, Wondea [KAERI, Daejeon (Korea, Republic of); Seong, Poong Hyun [KAIST, Daejeon (Korea, Republic of)

    2015-05-15

    The Technique for Human Error Rate Prediction (THERP), Korean Human Reliability Analysis (K-HRA), Human Error Assessment and Reduction Technique (HEART), A Technique for Human Event Analysis (ATHEANA), Cognitive Reliability and Error Analysis Method (CREAM), and Simplified Plant Analysis Risk Human Reliability Assessment (SPAR-H) in relation to NPP maintenance and operation. Most of these methods were developed considering the conventional type of Main Control Rooms (MCRs). They are still used for HRA in advanced MCRs even though the operating environment of advanced MCRs in NPPs has been considerably changed by the adoption of new human-system interfaces such as computer-based soft controls. Among the many features in advanced MCRs, soft controls are an important feature because the operation action in NPP advanced MCRs is performed by soft controls. Consequently, those conventional methods may not sufficiently consider the features of soft control execution human errors. To this end, a new framework of a HRA method for evaluating soft control execution human error is suggested by performing the soft control task analysis and the literature reviews regarding widely accepted human error taxonomies. In this study, the framework of a HRA method for evaluating soft control execution human error in advanced MCRs is developed. First, the factors which HRA method in advanced MCRs should encompass are derived based on the literature review, and soft control task analysis. Based on the derived factors, execution HRA framework in advanced MCRs is developed mainly focusing on the features of soft control. Moreover, since most current HRA database deal with operation in conventional type of MCRs and are not explicitly designed to deal with digital HSI, HRA database are developed under lab scale simulation.

  19. Antimicrobial Materials for Advanced Microbial Control in Spacecraft Water Systems

    Science.gov (United States)

    Birmele, Michele; Caro, Janicce; Newsham, Gerard; Roberts, Michael; Morford, Megan; Wheeler, Ray

    2012-01-01

    Microbial detection, identification, and control are essential for the maintenance and preservation of spacecraft water systems. Requirements set by NASA put limitations on the energy, mass, materials, noise, cost, and crew time that can be devoted to microbial control. Efforts are being made to attain real-time detection and identification of microbial contamination in microgravity environments. Research for evaluating technologies for capability enhancement on-orbit is currently focused on the use of adenosine triphosphate (ATP) analysis for detection purposes and polymerase chain reaction (peR) for microbial identification. Additional research is being conducted on how to control for microbial contamination on a continual basis. Existing microbial control methods in spacecraft utilize iodine or ionic silver biocides, physical disinfection, and point-of-use sterilization filters. Although these methods are effective, they require re-dosing due to loss of efficacy, have low human toxicity thresholds, produce poor taste, and consume valuable mass and crew time. Thus, alternative methods for microbial control are needed. This project also explores ultraviolet light-emitting diodes (UV-LEDs), surface passivation methods for maintaining residual biocide levels, and several antimicrobial materials aimed at improving current microbial control techniques, as well as addressing other materials presently under analysis and future directions to be pursued.

  20. Advanced dc motor controller for battery-powered electric vehicles

    Science.gov (United States)

    Belsterling, C. A.

    1981-01-01

    A motor generation set is connected to run from the dc source and generate a voltage in the traction motor armature circuit that normally opposes the source voltage. The functional feasibility of the concept is demonstrated with tests on a Proof of Principle System. An analog computer simulation is developed, validated with the results of the tests, applied to predict the performance of a full scale Functional Model dc Controller. The results indicate high efficiencies over wide operating ranges and exceptional recovery of regenerated energy. The new machine integrates both motor and generator on a single two bearing shaft. The control strategy produces a controlled bidirectional plus or minus 48 volts dc output from the generator permitting full control of a 96 volt dc traction motor from a 48 volt battery, was designed to control a 20 hp traction motor. The controller weighs 63.5 kg (140 lb.) and has a peak efficiency of 90% in random driving modes and 96% during the SAE J 227a/D driving cycle.

  1. Whole-Genome Microarray and Gene Deletion Studies Reveal Regulation of the Polyhydroxyalkanoate Production Cycle by the Stringent Response in Ralstonia eutropha H16

    Energy Technology Data Exchange (ETDEWEB)

    Brigham, CJ; Speth, DR; Rha, C; Sinskey, AJ

    2012-10-22

    Poly(3-hydroxybutyrate) (PHB) production and mobilization in Ralstonia eutropha are well studied, but in only a few instances has PHB production been explored in relation to other cellular processes. We examined the global gene expression of wild-type R. eutropha throughout the PHB cycle: growth on fructose, PHB production using fructose following ammonium depletion, and PHB utilization in the absence of exogenous carbon after ammonium was resupplied. Our results confirm or lend support to previously reported results regarding the expression of PHB-related genes and enzymes. Additionally, genes for many different cellular processes, such as DNA replication, cell division, and translation, are selectively repressed during PHB production. In contrast, the expression levels of genes under the control of the alternative sigma factor sigma(54) increase sharply during PHB production and are repressed again during PHB utilization. Global gene regulation during PHB production is strongly reminiscent of the gene expression pattern observed during the stringent response in other species. Furthermore, a ppGpp synthase deletion mutant did not show an accumulation of PHB, and the chemical induction of the stringent response with DL-norvaline caused an increased accumulation of PHB in the presence of ammonium. These results indicate that the stringent response is required for PHB accumulation in R. eutropha, helping to elucidate a thus-far-unknown physiological basis for this process.

  2. Development of an implantable myoelectric sensor for advanced prosthesis control.

    Science.gov (United States)

    Merrill, Daniel R; Lockhart, Joseph; Troyk, Phil R; Weir, Richard F; Hankin, David L

    2011-03-01

    Modern hand and wrist prostheses afford a high level of mechanical sophistication, but the ability to control them in an intuitive and repeatable manner lags. Commercially available systems using surface electromyographic (EMG) or myoelectric control can supply at best two degrees of freedom (DOF), most often sequentially controlled. This limitation is partially due to the nature of surface-recorded EMG, for which the signal contains components from multiple muscle sources. We report here on the development of an implantable myoelectric sensor using EMG sensors that can be chronically implanted into an amputee's residual muscles. Because sensing occurs at the source of muscle contraction, a single principal component of EMG is detected by each sensor, corresponding to intent to move a particular effector. This system can potentially provide independent signal sources for control of individual effectors within a limb prosthesis. The use of implanted devices supports inter-day signal repeatability. We report on efforts in preparation for human clinical trials, including animal testing, and a first-in-human proof of principle demonstration where the subject was able to intuitively and simultaneously control two DOF in a hand and wrist prosthesis.

  3. Advances in soft computing, intelligent robotics and control

    CERN Document Server

    Fullér, Robert

    2014-01-01

    Soft computing, intelligent robotics and control are in the core interest of contemporary engineering. Essential characteristics of soft computing methods are the ability to handle vague information, to apply human-like reasoning, their learning capability, and ease of application. Soft computing techniques are widely applied in the control of dynamic systems, including mobile robots. The present volume is a collection of 20 chapters written by respectable experts of the fields, addressing various theoretical and practical aspects in soft computing, intelligent robotics and control. The first part of the book concerns with issues of intelligent robotics, including robust xed point transformation design, experimental verification of the input-output feedback linearization of differentially driven mobile robot and applying kinematic synthesis to micro electro-mechanical systems design. The second part of the book is devoted to fundamental aspects of soft computing. This includes practical aspects of fuzzy rule ...

  4. Advances in Inertial Measurement Technology for Marine Motion Control

    Directory of Open Access Journals (Sweden)

    Mathias Håndlykken

    1996-01-01

    Full Text Available This paper describes the function of an inertial "strap down" attitude sensor based on solid state Coriolis force rate gyros, accelerometers and magnetic sensor. Performance is analyzed taking into account the typical excitations in attitude and linear motion seen in marine applications. The use is for control of fast crafts, ROV and AUV heading, roll, pitch and heave control. The influence on performance given by utilization of external information from velocity log and more accurate heading devices is also analyzed. Typical performance of this low cost type of technology is shown.

  5. Advanced and intelligent computations in diagnosis and control

    CERN Document Server

    2016-01-01

    This book is devoted to the demands of research and industrial centers for diagnostics, monitoring and decision making systems that result from the increasing complexity of automation and systems, the need to ensure the highest level of reliability and safety, and continuing research and the development of innovative approaches to fault diagnosis. The contributions combine domains of engineering knowledge for diagnosis, including detection, isolation, localization, identification, reconfiguration and fault-tolerant control. The book is divided into six parts:  (I) Fault Detection and Isolation; (II) Estimation and Identification; (III) Robust and Fault Tolerant Control; (IV) Industrial and Medical Diagnostics; (V) Artificial Intelligence; (VI) Expert and Computer Systems.

  6. Advanced Control Architectures for Intelligent Microgrids—Part II

    DEFF Research Database (Denmark)

    Guerrero, Josep M.; Chiang Loh, Poh; Lee, Tzung-Lin;

    2013-01-01

    This paper summarizes the main problems and solutions of power quality in microgrids, distributed-energy-storage systems, and ac/dc hybrid microgrids. First, the power quality enhancement of grid-interactive microgrids is presented. Then, the cooperative control for enhance voltage harmonics...... and unbalances in microgrids is reviewed. Afterward, the use of static synchronous compensator (STATCOM) in grid-connected microgrids is introduced in order to improve voltage sags/swells and unbalances. Finally, the coordinated control of distributed storage systems and ac/dc hybrid microgrids is explained....

  7. Sleeper cells: the stringent response and persistence in the Borreliella (Borrelia) burgdorferi enzootic cycle.

    Science.gov (United States)

    Cabello, Felipe C; Godfrey, Henry P; Bugrysheva, Julia V; Newman, Stuart A

    2017-08-24

    Infections with tick-transmitted Borreliella (Borrelia) burgdorferi, the cause of Lyme disease, represent an increasingly large public health problem in North America and Europe. The ability of these spirochetes to maintain themselves for extended periods of time in their tick vectors and vertebrate reservoirs is crucial for continuance of the enzootic cycle as well as for the increasing exposure of humans to them. The stringent response mediated by the alarmone (p)ppGpp has been determined to be a master regulator in B. burgdorferi. It modulates the expression of identified and unidentified open reading frames needed to deal with and overcome the many nutritional stresses and other challenges faced by the spirochete in ticks and animal reservoirs. The metabolic and morphologic changes resulting from activation of the stringent response in B. burgdorferi may also be involved in the recently described non-genetic phenotypic phenomenon of tolerance to otherwise lethal doses of antimicrobials and to other antimicrobial activities. It may thus constitute a linchpin in multiple aspects of infections with Lyme disease borrelia, providing a link between the micro-ecological challenges of its enzootic life-cycle and long-term residence in the tissues of its animal reservoirs, with the evolutionary side effect of potential persistence in incidental human hosts. © 2017 Society for Applied Microbiology and John Wiley & Sons Ltd.

  8. Prospects for advancing tuberculosis control efforts through novel therapies

    NARCIS (Netherlands)

    J.A. Salomon; J.O. Lloyd-Smith; W.M. Getz; S. Resch; M.S. Sanchez; T.C. Porco; M.W. Borgdorff

    2006-01-01

    Background Development of new, effective, and affordable tuberculosis ( TB) therapies has been identified as a critical priority for global TB control. As new candidates emerge from the global TB drug pipeline, the potential impacts of novel, shorter regimens on TB incidence and mortality have not y

  9. Advanced, Integrated Control for Building Operations to Achieve 40% Energy Saving

    Energy Technology Data Exchange (ETDEWEB)

    Lu, Yan; Song, Zhen; Loftness, Vivian; Ji, Kun; Zheng, Sam; Lasternas, Bertrand; Marion, Flore; Yuebin, Yu

    2012-10-15

    We developed and demonstrated a software based integrated advanced building control platform called Smart Energy Box (SEB), which can coordinate building subsystem controls, integrate variety of energy optimization algorithms and provide proactive and collaborative energy management and control for building operations using weather and occupancy information. The integrated control system is a low cost solution and also features: Scalable component based architecture allows to build a solution for different building control system configurations with needed components; Open Architecture with a central data repository for data exchange among runtime components; Extendible to accommodate variety of communication protocols. Optimal building control for central loads, distributed loads and onsite energy resource; uses web server as a loosely coupled way to engage both building operators and building occupants in collaboration for energy conservation. Based on the open platform of SEB, we have investigated and evaluated a variety of operation and energy saving control strategies on Carnegie Mellon University Intelligent Work place which is equipped with alternative cooling/heating/ventilation/lighting methods, including radiant mullions, radiant cooling/heating ceiling panels, cool waves, dedicated ventilation unit, motorized window and blinds, and external louvers. Based on the validation results of these control strategies, they were integrated in SEB in a collaborative and dynamic way. This advanced control system was programmed and computer tested with a model of the Intelligent Workplace's northern section (IWn). The advanced control program was then installed in the IWn control system; the performance was measured and compared with that of the state of the art control system to verify the overall energy savings great than 40%. In addition advanced human machine interfaces (HMI's) were developed to communicate both with building

  10. Advanced Control and Protection system Design Methods for Modular HTGRs

    Energy Technology Data Exchange (ETDEWEB)

    Ball, Sydney J [ORNL; Wilson Jr, Thomas L [ORNL; Wood, Richard Thomas [ORNL

    2012-06-01

    The project supported the Nuclear Regulatory Commission (NRC) in identifying and evaluating the regulatory implications concerning the control and protection systems proposed for use in the Department of Energy's (DOE) Next-Generation Nuclear Plant (NGNP). The NGNP, using modular high-temperature gas-cooled reactor (HTGR) technology, is to provide commercial industries with electricity and high-temperature process heat for industrial processes such as hydrogen production. Process heat temperatures range from 700 to 950 C, and for the upper range of these operation temperatures, the modular HTGR is sometimes referred to as the Very High Temperature Reactor or VHTR. Initial NGNP designs are for operation in the lower temperature range. The defining safety characteristic of the modular HTGR is that its primary defense against serious accidents is to be achieved through its inherent properties of the fuel and core. Because of its strong negative temperature coefficient of reactivity and the capability of the fuel to withstand high temperatures, fast-acting active safety systems or prompt operator actions should not be required to prevent significant fuel failure and fission product release. The plant is designed such that its inherent features should provide adequate protection despite operational errors or equipment failure. Figure 1 shows an example modular HTGR layout (prismatic core version), where its inlet coolant enters the reactor vessel at the bottom, traversing up the sides to the top plenum, down-flow through an annular core, and exiting from the lower plenum (hot duct). This research provided NRC staff with (a) insights and knowledge about the control and protection systems for the NGNP and VHTR, (b) information on the technologies/approaches under consideration for use in the reactor and process heat applications, (c) guidelines for the design of highly integrated control rooms, (d) consideration for modeling of control and protection system designs

  11. Evaluation of information display at advanced main control room

    Energy Technology Data Exchange (ETDEWEB)

    Min, Dai Hwan; Jo, Heon Jin; Jeon, Byung Ho [Korea Univ., Seoul (Korea, Republic of)

    2001-03-15

    The purpose of this research is first to establish an evaluation method for CBPs(Computer-Based Procedures) at the advanced MCR as a part of regulation technology for the safety of KNGR. The second purpose is to design a prototype of a support system for the evaluation. We have selected the guideline method for the evaluation, since currently there is not any better alternative. Several guidelines have been published for the design of CBPs. The guidelines include both guidance for CBP design process review and guidance for CBP design product review. Although CBPs have many advantages over PBPs(Pater-Based Procedures), they have some drawbacks since CBPs show the information on display screens instead of papers, and generate some new issues that have not been raised with PBPs. For the new issues, we need to be cautious because it is hard to generalize the effects of CBPs and there is no conclusive answer yet. A support system is necessary for the evaluation of CBPs, since it is not easy to carry out an evaluation task even though an evaluator has firm background on cognitive engineering theories and practical experiences. The support system is going to have web-style interface and databases of evaluation items, guidelines for each evaluation item, and technical bases from which a guideline is derived. Evaluation items include those for desirable feature of CBPs and those for a subjective evaluation by the operating crew. The support system will facilitate the task of evaluators by linking evaluation items with technical basis and by providing features for recording and tracing the evaluation result and efforts for resolving the issues identified.

  12. ADVANCES IN ESTIMATION AND CONTROL FOR FLOTATION COLUMNS

    OpenAIRE

    2010-01-01

    Flotation is multivariable process exhibiting uncertain and nonlinear dynamics as well as being perturbed by unmeasured disturbances. Optimization of this process is therefore a complex undertaking. Although real-time optimization (RTO) techniques for maximizing an objective function are aailable, steady-state assumptions in processes being frequently acted upon by unmeasured distrubances, strongly limit the optimization frequency, hierachical control systems allow to efficiently dealing with...

  13. An Advanced Control System for Fine Coal Floatation

    Energy Technology Data Exchange (ETDEWEB)

    Luttrell, G H; Adel, G T

    1998-06-01

    A model-based flotation control scheme is being implemented to achieve optimal performance in the handling and treatment of fine coal. The control scheme monitors flotation performance through on-line analysis of ash content. Then, based on the economic and metallurgical performance of the circuit, variables such as collector dosage, frother dosage, and pulp level are adjusted using model-based control algorithms to compensate for feed variations and other process disturbances. Recent developments in sensor technology are being applied for on-line determination of slurry ash content. During the eighth quarter of this project, the analysis of data collected during Task 2 (Sampling and Data Analysis) was completed, and significant progress was made on Task 3 (Model Building and Computer Simulation). Previously, a plant sampling campaign had been conducted at Pittston's Moss No. 3 preparation plant to provide data for the development of a mathematical process model and a model-based control system. During this campaign, a one-half factorial design experiment, blocked into low and high feed rates, was conducted to investigate the effects of collector, frother, and pulp level on model parameters. In addition, samples were collected during the transient period following each change in the manipulated variables to provide data for confirmation of the dynamic process simulator. A residence time distribution (RTD) test was also conducted to estimate the mean residence time. This is a critical piece of information since no feed flowrate measurement is available, and the mean residence time can be used to estimate the feed flowrate. Feed samples were taken at timed intervals and floated in a laboratory flotation cell to investigate the magnitude of feed property disturbances and their duration.

  14. Recent advances in sliding modes from control to intelligent mechatronics

    CERN Document Server

    Efe, Mehmet

    2015-01-01

    This volume is dedicated to Professor Okyay Kaynak to commemorate his life time impactful research and scholarly achievements and outstanding services to profession. The 21 invited chapters have been written by leading researchers who, in the past, have had association with Professor Kaynak as either his students and associates or colleagues and collaborators. The focal theme of the volume is the Sliding Modes covering a broad scope of topics from theoretical investigations to their significant applications from Control to Intelligent Mechatronics.  

  15. System design and control integration for advanced manufacturing

    CERN Document Server

    Li, Han-Xiong

    2014-01-01

    Most existing robust design books address design for static systems, or achieve robust design from experimental data via the Taguchi method. Little work considers model information for robust design particularly for the dynamic system. This book covers robust design for both static and dynamic systems using the nominal model information or the hybrid model/data information, and also integrates design with control under a large operating region. This design can handle strong nonlinearity and more uncertainties from model and parameters.

  16. Grid Monitoring and Advanced Control of Distributed Power Generation Systems

    OpenAIRE

    Timbus, Adrian Vasile

    2007-01-01

    The movement towards a clean technology for energy production and the constraints in reducing the CO2 emissions are some factors facilitating the growth of distributed power generation systems based on renewable energy resources. Consequently, large penetration of distributed generators has been reported in some countries creating concerns about power system stability. This leads to a continuous evolution of grid interconnection requirements towards a better controllability of generated power...

  17. ADVANCED SULFUR CONTROL CONCEPTS FOR HOT GAS DESULFURIZATION TECHNOLOGY

    Energy Technology Data Exchange (ETDEWEB)

    Unknown

    1999-04-01

    The objective of this project is to develop a hot-gas desulfurization process scheme for control of H{sub 2}S in HTHP coal gas that can be more simply and economically integrated with known regenerable sorbents in DOE/METC-sponsored work than current leading hot-gas desulfurization technologies. In addition to being more economical, the process scheme to be developed must yield an elemental sulfur byproduct.

  18. ADVANCED SULFUR CONTROL CONCEPTS FOR HOT GAS DESULFURIZATION TECHNOLOGY

    Energy Technology Data Exchange (ETDEWEB)

    None

    1998-12-31

    The objective of this project is to develop a hot-gas desulfurization process scheme for control of H{sub 2}S in HTHP coal gas that can be more simply and economically integrated with known regenerable sorbents in DOE/METC-sponsored work than current leading hot-gas desulfurization technologies. In addition to being more economical, the process scheme to be developed must yield an elemental sulfur byproduct.

  19. Advancement in modern approaches to mineral production quality control

    Science.gov (United States)

    Freidina, EV; Botvinnik, AA; Dvornikova, AN

    2017-02-01

    The natural resource potential of mineral deposits is represented by three categories: upside, attainable and investment. A modern methodology is proposed in this paper for production quality control, and its tools aimed at ensuring agreement between the product quality and the market requirements are described. The definitions of the costs of the product quality compliance and incompliance with the consumer requirements are introduced; the latter is suggested to use in evaluating resource potential of mineral deposits at a certain degree of probability.

  20. Strategy for Advanced Sensing and Control of Combustion.

    Science.gov (United States)

    1986-02-06

    leads to a stable closed-loop system A satisfactory stability criterion might be the off-axis circle criterion [Hedrick and Paynter. 1980]. This...shown in Figure 2 to the system shown in Figure 3. Figure 3 represents a system with simple proportional control. The off-axis circle criterion requires...Application of the off-axis circle criterion to the Nyquist curves in Figure 4 suggests that the gain, k , that can be tolerated by the system of Figure

  1. Advanced Controls for Residential Whole-House Ventilation Systems

    Energy Technology Data Exchange (ETDEWEB)

    Turner, William [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Walker, Iain [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Sherman, Max [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States)

    2014-08-01

    Whole-house ventilation systems are becoming commonplace in new construction, remodeling/renovation, and weatherization projects, driven by combinations of specific requirements for indoor air quality (IAQ), health and compliance with standards, such as ASHRAE 62.2. Ventilation systems incur an energy penalty on the home via fan power used to drive the airflow, and the additional space-conditioning load associated with heating or cooling the ventilation air. Finding a balance between IAQ and energy use is important if homes are to be adequately ventilated while not increasing the energy burden. This study used computer simulations to examine RIVEC the Residential Integrated Ventilation Controller - a prototype ventilation controller that aims to deliver whole-house ventilation rates that comply with ventilation standards, for the minimum use of energy. Four different whole-house ventilation systems were simulated, both with and without RIVEC, so that the energy and IAQ results could be compared. Simulations were conducted for 13 US climate zones, three house designs, and three envelope leakage values. The results showed that the RIVEC controller could typically return ventilation energy savings greater than 40percent without compromising long-term chronic or short-term acute exposures to relevant indoor contaminants. Critical and average peak power loads were also reduced as a consequence of using RIVEC.

  2. Advanced transport operating system software upgrade: Flight management/flight controls software description

    Science.gov (United States)

    Clinedinst, Winston C.; Debure, Kelly R.; Dickson, Richard W.; Heaphy, William J.; Parks, Mark A.; Slominski, Christopher J.; Wolverton, David A.

    1988-01-01

    The Flight Management/Flight Controls (FM/FC) software for the Norden 2 (PDP-11/70M) computer installed on the NASA 737 aircraft is described. The software computes the navigation position estimates, guidance commands, those commands to be issued to the control surfaces to direct the aircraft in flight based on the modes selected on the Advanced Guidance Control System (AGSC) mode panel, and the flight path selected via the Navigation Control/Display Unit (NCDU).

  3. Design and Advanced Control of Switched Reluctance Motors

    DEFF Research Database (Denmark)

    Rasmussen, Peter Omand

    with SR technology is the reputation of the high acoustic noise emission compared to other electrical machines. Therefore, extra focus to analyze this specific subject is done. The major origin to the high level of acoustic noise is due to highly concentrated normal forces with a high harmonic content...... with the control strategy and the output is the sound pressure at the top of the stator yoke. This is presented as both a technical A-weighted value and as a subjective value in form of the sound from the PC having the SRDaS program installed. The developed acoustic models are also verified in practice on several...

  4. Towards energy efficient operation of Heating, Ventilation and Air Conditioning systems via advanced supervisory control design

    Science.gov (United States)

    Oswiecinska, A.; Hibbs, J.; Zajic, I.; Burnham, K. J.

    2015-11-01

    This paper presents conceptual control solution for reliable and energy efficient operation of heating, ventilation and air conditioning (HVAC) systems used in large volume building applications, e.g. warehouse facilities or exhibition centres. Advanced two-level scalable control solution, designed to extend capabilities of the existing low-level control strategies via remote internet connection, is presented. The high-level, supervisory controller is based on Model Predictive Control (MPC) architecture, which is the state-of-the-art for indoor climate control systems. The innovative approach benefits from using passive heating and cooling control strategies for reducing the HVAC system operational costs, while ensuring that required environmental conditions are met.

  5. Advanced induction motor drive control with single current sensor

    Directory of Open Access Journals (Sweden)

    Adžić Evgenije M.

    2016-01-01

    Full Text Available This paper proposes induction motor drive control method which uses minimal number of sensors, providing only DC-link current as a feedback signal. Improved DC-link current sampling scheme and modified asymmetrical switching pattern cancels characteristic waveform errors which exist in all three reconstructed motor line-currents. Motor linecurrent harmonic content is reduced to an acceptable level, eliminating torque and speed oscillations which were inherent for conventional single sensor drives. Consequently, use of single current sensor and line-current reconstruction technique is no longer acceptable only for low and medium performance drives, but also for drives where priority is obtaining a highly accurate, stable and fast response. Proposed control algorithm is validated using induction motor drive hardware prototype based on TMS320F2812 digital signal processor. [Projekat Ministarstva nauke Republike Srbije, br. III 042004 and by the Provincial Secretariat for Science and Technological Development of AP Vojvodina under contract No. 114-451-3508/2013-04

  6. Advanced Communication and Control Solutions of Distributed Energy Resources (DER)

    Energy Technology Data Exchange (ETDEWEB)

    Asgeirsson, Haukur; Seguin, Richard; Sherding, Cameron; de Bruet, Andre, G.; Broadwater, Robert; Dilek, Murat

    2007-01-10

    This report covers work performed in Phase II of a two phase project whose objective was to demonstrate the aggregation of multiple Distributed Energy Resources (DERs) and to offer them into the energy market. The Phase I work (DE-FC36-03CH11161) created an integrated, but distributed, system and procedures to monitor and control multiple DERs from numerous manufacturers connected to the electric distribution system. Procedures were created which protect the distribution network and personnel that may be working on the network. Using the web as the communication medium for control and monitoring of the DERs, the integration of information and security was accomplished through the use of industry standard protocols such as secure SSL,VPN and ICCP. The primary objective of Phase II was to develop the procedures for marketing the power of the Phase I aggregated DERs in the energy market, increase the number of DER units, and implement the marketing procedures (interface with ISOs) for the DER generated power. The team partnered with the Midwest Independent System Operator (MISO), the local ISO, to address the energy market and demonstrate the economic dispatch of DERs in response to market signals. The selection of standards-based communication technologies offers the ability of the system to be deployed and integrated with other utilities’ resources. With the use of a data historian technology to facilitate the aggregation, the developed algorithms and procedures can be verified, audited, and modified. The team has demonstrated monitoring and control of multiple DERs as outlined in phase I report including procedures to perform these operations in a secure and safe manner. In Phase II, additional DER units were added. We also expanded on our phase I work to enhance communication security and to develop the market model of having DERs, both customer and utility owned, participate in the energy market. We are proposing a two-part DER energy market model--a utility

  7. CFD evaluation of an advanced thrust vector control concept

    Science.gov (United States)

    Tiarn, Weihnurng; Cavalleri, Robert

    1990-01-01

    A potential concept that can offer an alternate method for thrust vector control of the Space Shuttle Solid Rocket Booster is the use of a cylindrical probe that is inserted (on demand) through the wall of the rocket nozzle. This Probe Thrust Vector Control (PTVC) concept is an alternate to that of a gimbaled nozzle or a Liquid Injection Thrust Vector (LITVC) system. The viability of the PTVC concept can be assessed either experimentally and/or with the use of CFD. A purely experimental assessment can be time consuming and expensive, whereas a CFD assessment can be very time- and cost-effective. Two key requirements of the proposed concept are PTVC vectoring performance and the active cooling requirements for the probe to maintain its thermal and structural integrity. An active thermal cooling method is the injection of coolant around the pheriphery of the probe. How much coolant is required and how this coolant distributes itself in the flow field is of major concern. The objective of the work reported here is the use of CFD to answer these question and in the design of test hardware to substantiate the results of the CFD predictions.

  8. Control and dynamic systems v.42 advances in theory and applications

    CERN Document Server

    Leonides, CT

    1991-01-01

    Control and Dynamic Systems: Advances in Theory and Applications, Volume 42: Analysis and Control System Techniques for Electric Power Systems, Part 2 of 4 covers the research studies on the significant advances in areas including economic operation of power systems and voltage and power control techniques.This book is composed of eight chapters and begins with a survey of the application of parallel processing to power system analysis as motivated by the requirement for faster computation. The next chapters deal with the issues of power system protection from a system point of view, t

  9. International Workshop on Advanced Dynamics and Model Based Control of Structures and Machines

    CERN Document Server

    Belyaev, Alexander; Krommer, Michael

    2017-01-01

    The papers in this volume present and discuss the frontiers in the mechanics of controlled machines and structures. They are based on papers presented at the International Workshop on Advanced Dynamics and Model Based Control of Structures and Machines held in Vienna in September 2015. The workshop continues a series of international workshops held in Linz (2008) and St. Petersburg (2010).

  10. Advanced Dynamics and Model-Based Control of Structures and Machines

    CERN Document Server

    Krommer, Michael; Belyaev, Alexander

    2012-01-01

    The book contains 26 scientific contributions by leading experts from Russia, Austria, Italy, Japan and Taiwan. It presents an overview on recent developments in Advanced Dynamics and Model Based Control of Structures and Machines. Main topics are nonlinear control of structures and systems, sensing and actuation, active and passive damping, nano- and micromechanics, vibrations and waves.

  11. Advanced underground Vehicle Power and Control: The locomotive Research Platform

    Energy Technology Data Exchange (ETDEWEB)

    Vehicle Projects LLC

    2003-01-28

    Develop a fuelcell mine locomotive with metal-hydride hydrogen storage. Test the locomotive for fundamental limitations preventing successful commercialization of hydride fuelcells in underground mining. During Phase 1 of the DOE-EERE sponsored project, FPI and its partner SNL, completed work on the development of a 14.4 kW fuelcell power plant and metal-hydride energy storage. An existing battery-electric locomotive with similar power requirements, minus the battery module, was used as the base vehicle. In March 2001, Atlas Copco Wagner of Portland, OR, installed the fuelcell power plant into the base vehicle and initiated integration of the system into the vehicle. The entire vehicle returned to Sandia in May 2001 for further development and integration. Initial system power-up took place in December 2001. A revision to the original contract, Phase 2, at the request of DOE Golden Field Office, established Vehicle Projects LLC as the new prime contractor,. Phase 2 allowed industry partners to conduct surface tests, incorporate enhancements to the original design by SNL, perform an extensive risk and safety analysis, and test the fuelcell locomotive underground under representative production mine conditions. During the surface tests one of the fuelcell stacks exhibited reduced power output resulting in having to replace both fuelcell stacks. The new stacks were manufactured with new and improved technology resulting in an increase of the gross power output from 14.4 kW to 17 kW. Further work by CANMET and Hatch Associates, an engineering consulting firm specializing in safety analysis for the mining industry, both under subcontract to Vehicle Projects LLC, established minimum requirements for underground testing. CANMET upgraded the Programmable Logic Control (PLC) software used to monitor and control the fuelcell power plant, taking into account locomotive operator's needs. Battery Electric, a South Africa manufacturer, designed and manufactured (at no cost

  12. Advanced Control of Active Bearings - Modelling, Design and Experiments

    DEFF Research Database (Denmark)

    Theisen, Lukas Roy Svane

    In all rotating machines relative movements between the stationary parts and the rotating parts imply energy loss and, in many critical cases, vibration problems. This energy loss leads to higher overall energy consumption of the system. Research activities towards the reduction of friction......, the enhancement of damping, the extension of operating range and the minimisation of critical vibrations in machine elements are of fundamental importance. The main component to tackle the energy-loss-related problems is the bearing. The area of design of active bearings, while very promising, is still in its...... the critical speeds. The feedback control law is preferably designed from a simple model, which captures the dominant dynamics of the machine in the frequency range of interest. This thesis offers two main original contributions in the field of active bearings. First, an experimental technique is proposed...

  13. OLED Luminaire with Panel Integrated Drivers and Advanced Controls

    Energy Technology Data Exchange (ETDEWEB)

    Lu, Michael [Acuity Brands Lighting, Inc., Atlanta, GA (United States); Spindler, Jeff [OLEDWorks, Rochester, NY (United States)

    2017-01-31

    For this DOE award, Acuity Brands Lighting developed a novel OLED luminaire system featuring panel-integrated drivers at each individual OLED panel. The luminaire has a base station that receives user commands and performs AC/DC conversion. A power line communication (PLC) protocol is used to provide both power and digital control to each panel. A 66-panel CanvisTM luminaire using state-of-art OLED panels based on this system was successfully constructed. This is a first demonstration of such a luminaire architecture. It is also the first known implementation of this number of independently addressable nodes with a PLC protocol. This luminaire system architecture has added benefits in the flexibility of using multiple panel vendors for a given product, forward compatibility with future panels, and reduced luminaire wiring complexity and assembly time.

  14. Demonstrating Compliance with Stringent Nitrogen Limits Using a Biological Nutrient Removal Process in California's Central Valley.

    Science.gov (United States)

    Merlo, Rion; Witzgall, Bob; Yu, William; Ohlinger, Kurt; Ramberg, Steve; De Las Casas, Carla; Henneman, Seppi; Parker, Denny

    2015-12-01

    The Sacramento Regional County Sanitation District (District) must be compliant with stringent nitrogen limits by 2021 that the existing treatment facilities cannot meet. An 11-month pilot study was conducted to confirm that these limits could be met with an air activated sludge biological nutrient removal (BNR) process. The pilot BNR treated an average flow of 946 m(3)/d and demonstrated that it could reliably meet the ammonia limit, but that external carbon addition may be necessary to satisfy the nitrate limit. The BNR process performed well throughout the 11 months of operation with good settleability, minimal nocardioform content, and high quality secondary effluent. The BNR process was operated at a minimum pH of 6.4 with no noticeable impact to nitrification rates. Increased secondary sludge production was observed during rainfall events and is attributed to a change in wastewater influent characteristics.

  15. Microbial pathogen control in the beef chain: recent research advances.

    Science.gov (United States)

    Buncic, Sava; Nychas, George-John; Lee, Michael R F; Koutsoumanis, Kostas; Hébraud, Michel; Desvaux, Mickaël; Chorianopoulos, Nikos; Bolton, Declan; Blagojevic, Bojan; Antic, Dragan

    2014-07-01

    Within a recent EU research project ("ProSafeBeef"), research on foodborne pathogens in the beef chain was conducted by using a longitudinally integrated (fork-to-farm) approach. There is not any "single intervention-single chain point" combination by which the pathogens would be reliably and entirely eliminated from the chain resulting in total prevention of pathogens in beef and products thereof at the consumption time. Rather, a range of control interventions have to be applied at multiple points of the chain, so to achieve an acceptable, ultimate risk reduction. Various novel interventions were developed and evaluated during the project, and are briefly summarized in this paper. They include on-farm measures, risk categorisation of cattle presented for slaughter, hygiene-based measures and antimicrobial treatments applied on hides and/or carcasses during cattle slaughter, those applied during beef processing-storage-distribution, use of Time Temperature Integrator-based indicators of safety, and effective sanitation of surfaces. Copyright © 2013 Elsevier Ltd. All rights reserved.

  16. Advances in understanding and utilising ELM control in JET

    Science.gov (United States)

    Chapman, I. T.; de la Luna, E.; Lang, P. T.; Liang, Y.; Alper, B.; Denner, P.; Frigione, D.; Garzotti, L.; Ham, C. J.; Huijsmans, G. T. A.; Jachmich, S.; Kocsis, G.; Lennholm, M.; Lupelli, I.; Rimini, F. G.; Sips, A. C. C.; Contributors, JET

    2016-01-01

    Edge localised mode (ELM) control may be essential to develop ITER scenarios with a reasonable lifetime of divertor components, whilst ELM pacing may be essential to develop stationary ITER scenarios with a tungsten divertor. Resonant magnetic perturbations (RMPs) have mitigated ELMs in high collisionality plasmas in JET. The efficacy of RMPs in mitigating the ELMs is found to depend on plasma shaping, with the change in magnetic boundary achieved when non-axisymmetric fields are applied facilitating access to small ELM regimes. The understanding of ELM pacing by vertical kicks or pellets has also been improved in a range of pedestal conditions in JET ({{T}\\text{ped}}=0.7 -1.3 keV) encompassing the ITER-expected domain ({β\\text{N}}=1.4 -2.4, H 98(y, 2)  =  0.8-1.2, {{f}\\text{GW}}˜ 0.7 ). ELM triggering is reliable provided the perturbation is above a threshold which depends on pedestal parameters. ELM triggering is achieved even in the first 10% of the natural ELM cycle suggesting no inherent maximum frequency. At high normalised pressure, the peeling-ballooning modes are stabilised as predicted by ELITE, necessitating a larger perturbation from either kicks or pellets in order to trigger ELMs. Both kicks and pellets have been used to pace ELMs for tungsten flushing. This has allowed stationary plasma conditions with low gas injection in plasmas where the natural ELM frequency is such that it would normally preclude stationary conditions.

  17. Prospects for advancing tuberculosis control efforts through novel therapies.

    Directory of Open Access Journals (Sweden)

    Joshua A Salomon

    2006-08-01

    Full Text Available BACKGROUND: Development of new, effective, and affordable tuberculosis (TB therapies has been identified as a critical priority for global TB control. As new candidates emerge from the global TB drug pipeline, the potential impacts of novel, shorter regimens on TB incidence and mortality have not yet been examined. METHODS AND FINDINGS: We used a mathematical model of TB to evaluate the expected benefits of shortening the duration of effective chemotherapy for active pulmonary TB. First, we considered general relationships between treatment duration and TB dynamics. Next, as a specific example, we calibrated the model to reflect the current situation in the South-East Asia region. We found that even with continued and rapid progress in scaling up the World Health Organization's DOTS strategy of directly observed, short-course chemotherapy, the benefits of reducing treatment duration would be substantial. Compared to a baseline of continuing DOTS coverage at current levels, and with currently available tools, a 2-mo regimen introduced by 2012 could prevent around 20% (range 13%-28% of new cases and 25% (range 19%-29% of TB deaths in South-East Asia between 2012 and 2030. If effective treatment with existing drugs expands rapidly, overall incremental benefits of shorter regimens would be lower, but would remain considerable (13% [range 8%-19%] and 19% [range 15%-23%] reductions in incidence and mortality, respectively, between 2012 and 2030. A ten-year delay in the introduction of new drugs would erase nearly three-fourths of the total expected benefits in this region through 2030. CONCLUSIONS: The introduction of new, shorter treatment regimens could dramatically accelerate the reductions in TB incidence and mortality that are expected under current regimens-with up to 2- or 3-fold increases in rates of decline if shorter regimens are accompanied by enhanced case detection. Continued progress in reducing the global TB burden will require a

  18. Advanced topics in control and estimation of state-multiplicative noisy systems

    CERN Document Server

    Gershon, Eli

    2013-01-01

    Advanced Topics in Control and Estimation of State-Multiplicative Noisy Systems begins with an introduction and extensive literature survey. The text proceeds to cover solutions of measurement-feedback control and state problems and the formulation of the Bounded Real Lemma for both continuous- and discrete-time systems. The continuous-time reduced-order and stochastic-tracking control problems for delayed systems are then treated. Ideas of nonlinear stability are introduced for infinite-horizon systems, again, in both the continuous- and discrete-time cases. The reader is introduced to six practical examples of noisy state-multiplicative control and filtering associated with various fields of control engineering. The book is rounded out by a three-part appendix containing stochastic tools necessary for a proper appreciation of the text: a basic introduction to nonlinear stochastic differential equations and aspects of switched systems and peak to peak  optimal control and filtering. Advanced Topics in Contr...

  19. Guest Editorial Special Issue on Recent Advances and New Directions in Switched Control Systems

    Institute of Scientific and Technical Information of China (English)

    2006-01-01

    @@ As guest editors, it is our great honor to bring this special issue of the Journal of Control Theory and Applications devoted to Recent Advances and New Directions in Switched Control Systems. Recently, switched control systems have attracted much attention in the control systems community. Problems in this area are not only academically challenging for the inherent mathematical complexity, but also are derived or motivated from advanced applications in natural sciences, engineering, and social sciences. For survival, natural biological systems switch their survival strategies in accordance with environmental changes. For improved performance, switching has been extensively utilized/exploited in engineering systems such as automotive drive train control, electronic devices, control of power systems, etc.

  20. Contribution to the study and design of advanced controllers : application to smelting furnaces

    OpenAIRE

    Ojeda Sarmiento, Juan Manuel

    2013-01-01

    In this doctoral thesis, contributions to the study and design of advanced controllers and their application to metallurgical smelting furnaces are discussed. For this purpose, this kind of plants has been described in detail. The case of study is an Isasmelt plant in south Peru, which yearly processes 1.200.000 tons of copper concentrate. The current control system is implemented on a distributed control system. The main structure includes a cascade strategy to regulate the molten bath tempe...

  1. Advanced Control Scenario of High-Performance Steady-State Operation for JT-60 Superconducting Tokamak

    Institute of Scientific and Technical Information of China (English)

    H. Tamai; Y. Kamada; A. Sakasai; S. Ishida; G. Kurita; M. Matsukawa; K. Urata; S. Sakurai; K. Tsuchiya; A. Morioka; Y. M. Miura; K. Kizu

    2004-01-01

    Plasma control on high-βN steady-state operation for JT-60 superconducting modification is discussed. Accessibility to high-βN exceeding the free-boundary limit is investigated with the stabilising wall of reduced-activated ferritic steel and the active feedback control of the in-vessel non-axisymmetric field coils. Taking the merit of superconducting magnet, advanced plasma control for steady-state high performance operation could be expected.

  2. Gas-phase advanced oxidation for effective, efficient in situ control of pollution

    DEFF Research Database (Denmark)

    Johnson, Matthew Stanley; Nilsson, Elna Johanna Kristina; Svensson, Erik Anders

    2014-01-01

    In this article, gas-phase advanced oxidation, a new method for pollution control building on the photo-oxidation and particle formation chemistry occurring in the atmosphere, is introduced and characterized. The process uses ozone and UV-C light to produce in situ radicals to oxidize pollution....... The laboratory prototype was built of standard ventilation duct and could treat up to 850 m3/h. A portable continuous-flow prototype built in an aluminum flight case was able to treat 46 m3/h. Removal efficiencies of >95% were observed for propane, cyclohexane, benzene, isoprene, aerosol particle mass, and ozone...... on these results, in situ gas-phase advanced oxidation is a viable control strategy for most volatile organic compounds, specifically those with a OH* reaction rate higher than ca. 5 × 10-13 cm3/s. Gas-phase advanced oxidation is able to remove compounds that react with OH and to control ozone and total...

  3. Theoretical and algorithmic advances in multi-parametric programming and control

    KAUST Repository

    Pistikopoulos, Efstratios N.

    2012-04-21

    This paper presents an overview of recent theoretical and algorithmic advances, and applications in the areas of multi-parametric programming and explicit/multi-parametric model predictive control (mp-MPC). In multi-parametric programming, advances include areas such as nonlinear multi-parametric programming (mp-NLP), bi-level programming, dynamic programming and global optimization for multi-parametric mixed-integer linear programming problems (mp-MILPs). In multi-parametric/explicit MPC (mp-MPC), advances include areas such as robust multi-parametric control, multi-parametric nonlinear MPC (mp-NMPC) and model reduction in mp-MPC. A comprehensive framework for multi-parametric programming and control is also presented. Recent applications include a hydrogen storage device, a fuel cell power generation system, an unmanned autonomous vehicle (UAV) and a hybrid pressure swing adsorption (PSA) system. © 2012 Springer-Verlag.

  4. Advanced Gasification Mercury/Trace Metal Control with Monolith Traps

    Energy Technology Data Exchange (ETDEWEB)

    Musich, Mark; Swanson, Michael; Dunham, Grant; Stanislowski, Joshua

    2010-10-05

    Two Corning monoliths and a non-carbon-based material have been identified as potential additives for mercury capture in syngas at temperatures above 400°F and pressure of 600 psig. A new Corning monolith formulation, GR-F1-2189, described as an active sample appeared to be the best monolith tested to date. The Corning SR Liquid monolith concept continues to be a strong candidate for mercury capture. Both monolith types allowed mercury reduction to below 5-μg/m{sup 3} (~5 ppb), a current U.S. Department of Energy (DOE) goal for trace metal control. Preparation methods for formulating the SR Liquid monolith impacted the ability of the monolith to capture mercury. The Energy & Environmental Research Center (EERC)-prepared Noncarbon Sorbents 1 and 2 appeared to offer potential for sustained and significant reduction of mercury concentration in the simulated fuel gas. The Noncarbon Sorbent 1 allowed sustained mercury reduction to below 5-μg/m{sup 3} (~5 ppb). The non-carbon-based sorbent appeared to offer the potential for regeneration, that is, desorption of mercury by temperature swing (using nitrogen and steam at temperatures above where adsorption takes place). A Corning cordierite monolith treated with a Group IB metal offered limited potential as a mercury sorbent. However, a Corning carbon-based monolith containing prereduced metallic species similar to those found on the noncarbon sorbents did not exhibit significant or sustained mercury reduction. EERC sorbents prepared with Group IB and IIB selenide appeared to have some promise for mercury capture. Unfortunately, these sorbents also released Se, as was evidenced by the measurement of H2Se in the effluent gas. All sorbents tested with arsine or hydrogen selenide, including Corning monoliths and the Group IB and IIB metal-based materials, showed an ability to capture arsine or hydrogen selenide at 400°F and 600 psig. Based on current testing, the noncarbon metal-based sorbents appear to be the most

  5. ADVANCED GASIFICATION MERCURY/TRACE METAL CONTROL WITH MONOLITH TRAPS

    Energy Technology Data Exchange (ETDEWEB)

    Mark A. Musich; Michael L. Swanson; Grant E. Dunham; Joshua J. Stanislowski

    2010-07-31

    Two Corning monoliths and a non-carbon-based material have been identified as potential additives for mercury capture in syngas at temperatures above 400°F and pressure of 600 psig. A new Corning monolith formulation, GR-F1-2189, described as an active sample appeared to be the best monolith tested to date. The Corning SR Liquid monolith concept continues to be a strong candidate for mercury capture. Both monolith types allowed mercury reduction to below 5-μg/m3 (~5 ppb), a current U.S. Department of Energy (DOE) goal for trace metal control. Preparation methods for formulating the SR Liquid monolith impacted the ability of the monolith to capture mercury. The Energy & Environmental Research Center (EERC)-prepared Noncarbon Sorbents 1 and 2 appeared to offer potential for sustained and significant reduction of mercury concentration in the simulated fuel gas. The Noncarbon Sorbent 1 allowed sustained mercury reduction to below 5-μg/m3 (~5 ppb). The non-carbon-based sorbent appeared to offer the potential for regeneration, that is, desorption of mercury by temperature swing (using nitrogen and steam at temperatures above where adsorption takes place). A Corning cordierite monolith treated with a Group IB metal offered limited potential as a mercury sorbent. However, a Corning carbon-based monolith containing prereduced metallic species similar to those found on the noncarbon sorbents did not exhibit significant or sustained mercury reduction. EERC sorbents prepared with Group IB and IIB selenide appeared to have some promise for mercury capture. Unfortunately, these sorbents also released Se, as was evidenced by the measurement of H2Se in the effluent gas. All sorbents tested with arsine or hydrogen selenide, including Corning monoliths and the Group IB and IIB metal-based materials, showed an ability to capture arsine or hydrogen selenide at 400°F and 600 psig. Based on current testing, the noncarbon metal-based sorbents appear to be the most effective arsine

  6. Interior noise control ground test studies for advanced turboprop aircraft applications

    Science.gov (United States)

    Simpson, Myles A.; Cannon, Mark R.; Burge, Paul L.; Boyd, Robert P.

    1989-01-01

    The measurement and analysis procedures are documented, and the results of interior noise control ground tests conducted on a DC-9 aircraft test section are summarized. The objectives of these tests were to study the fuselage response characteristics of treated and untreated aircraft with aft-mount advanced turboprop engines and to analyze the effectiveness of selected noise control treatments in reducing passenger cabin noise on these aircraft. The results of fuselage structural mode surveys, cabin cavity surveys and sound intensity surveys are presented. The performance of various structural and cabin sidewall treatments is assessed, based on measurements of the resulting interior noise levels under simulated advanced turboprop excitation.

  7. Advanced Control Strategy of DFIG Wind Turbines for Power System Fault Ride Through

    DEFF Research Database (Denmark)

    Yang, Lihui; Xu, Zhao; Ostergaard, Jacob;

    2012-01-01

    This paper presents an advanced control strategy for the rotor and grid side converters of the doubly fed induction generator (DFIG) based wind turbine (WT) to enhance the low-voltage ride-through (LVRT) capability according to the grid connection requirement. Within the new control strategy...... the oscillations in the stator and rotor currents and the DC bus voltage. The effectiveness of the proposed control strategy has been demonstrated through various simulation cases. Compared with conventional crowbar protection, the proposed control method can not only improve the LVRT capability of the DFIG WT......, but also help maintaining continuous active and reactive power control of the DFIG during the grid faults....

  8. Review of advanced control rooms: Methodological considerations for the use of HFE guidelines

    Energy Technology Data Exchange (ETDEWEB)

    O`Hara, J.M.

    1994-03-01

    Control rooms for advanced nuclear power plants use advanced human-system interface (HSI) technologies that may have significant implications for plant safety in that they will affect the operator`s overall role in the system and the ways in which operators interact with the system. The US Nuclear Regulatory Commission (NRC) reviews HSIs to ensure that they are designed to accepted human factors engineering (HFE) principles. The principal review guidance, however, is more than ten-years old (US NRC, 1981). Accordingly, an Advanced HSI Design Review Guideline (DRG) was developed to provide criteria for these reviews. The DRG contains seven major sections: Information Display, User-System Interaction, Process Control and Input Devices, Alarms, Analysis and Decision Aids, Inter-Personnel Communication, and Workplace Design (see O`Hara & Brown, 1993). The purpose of this paper is to describe the methodology for DRG use.

  9. PREFACE: 12th European Workshop on Advanced Control and Diagnosis (ACD 2015)

    Science.gov (United States)

    Straka, Ondřej; Punčochář, Ivo; Duník, Jindřich

    2015-11-01

    The 12th European Workshop on Advanced Control and Diagnosis (ACD 2015) took place at the Research Centre NTIS - New Technologies for the Information Society, Faculty of Applied Sciences, University of West Bohemia, Pilsen, Czech Republic, on November 19 - 20, 2015. The annual European Workshop on Advanced Control and Diagnosis has been organized since 2003 by Control Engineering departments of several European universities in Germany, France, the UK, Poland, Italy, Hungary, and Denmark to bring together senior and junior academics and engineers from diverse fields of automatic control, fault detection, and signal processing. The workshop provides an opportunity for researchers and developers to present their recent theoretical developments, practical applications, or even open problems. It also offers a great opportunity for industrial partners to express their needs and priorities and to review the current activities in the fields. A total of 74 papers have been submitted for ACD 2015. Based on the peer reviews 48 papers were accepted for the oral presentation and 10 papers for the poster presentation. The accepted papers covered areas of control theory and applications, identification, estimation, signal processing, and fault detection. In addition, four excellent plenary lectures were delivered by Prof. Fredrik Gustafsson (Automotive Sensor Mining for Tire Pressure Monitoring), Prof. Vladimír Havlena (Advanced Process Control for Energy Efficiency), Prof. Silvio Simani (Advanced Issues on Wind Turbine Modelling and Control), and Prof. Robert Babuška (Learning Control in Robotics). The ACD 2015 was for the first time in the workshop history co-sponsored by the International Federation of Automatic Control (IFAC). On behalf of the ACD 2015 organising committee, we would like to thank all those who prepared and submitted papers, participated in the peer review process, supported, and attended the workshop.

  10. Field evaluation of advanced controls for the retrofit of packaged air conditioners and heat pumps

    Energy Technology Data Exchange (ETDEWEB)

    Wang, Weimin; Katipamula, Srinivas; Ngo, Hung; Underhill, Ronald M.; Taasevigen, Danny J.; Lutes, Robert G.

    2015-09-01

    This paper documents the magnitude of energy savings achievable in the field by retrofitting existing packaged rooftop units (RTUs) with advanced control strategies not ordinarily used for RTUs. A total of 66 RTUs on 8 different buildings were retrofitted with a commercially available advanced controller for improving RTU operational efficiency. The controller features enhanced air-side economizer control, multi-speed fan control, and demand controlled ventilation. Of the 66 RTUs, 18 are packaged heat pumps and the rest are packaged air conditioners with gas heat. The eight buildings cover four building types and four climate conditions. Based on the data collected for about a whole year, the advanced controller reduced the normalized annual RTU energy consumption between 22% and 90%, with an average of 57% for all RTUs. The average fractional savings uncertainty was 12% at 95% confidence level. Normalized annual electricity savings were in the range between 0.47 kWh/h (kWh per hour of RTU operation) and 7.21 kWh/h, with an average of 2.39 kWh/h. RTUs greater than 53 kW and runtime greater than 14 hours per day had payback periods less than 3 years even at $0.05/kWh.

  11. Development of Computational Approaches for Simulation and Advanced Controls for Hybrid Combustion-Gasification Chemical Looping

    Energy Technology Data Exchange (ETDEWEB)

    Joshi, Abhinaya; Lou, Xinsheng; Neuschaefer, Carl; Chaudry, Majid; Quinn, Joseph

    2012-07-31

    This document provides the results of the project through September 2009. The Phase I project has recently been extended from September 2009 to March 2011. The project extension will begin work on Chemical Looping (CL) Prototype modeling and advanced control design exploration in preparation for a scale-up phase. The results to date include: successful development of dual loop chemical looping process models and dynamic simulation software tools, development and test of several advanced control concepts and applications for Chemical Looping transport control and investigation of several sensor concepts and establishment of two feasible sensor candidates recommended for further prototype development and controls integration. There are three sections in this summary and conclusions. Section 1 presents the project scope and objectives. Section 2 highlights the detailed accomplishments by project task area. Section 3 provides conclusions to date and recommendations for future work.

  12. On the Controllability of a Differential Equation with Delayed and Advanced Arguments

    Directory of Open Access Journals (Sweden)

    Raúl Manzanilla

    2010-01-01

    Full Text Available A semigroup theory for a differential equation with delayed and advanced arguments is developed, with a detailed description of the infinitesimal generator. This in turn allows to study the exact controllability of the equation, by rewriting it as a classical Cauchy problem.

  13. Innovations in building regulation and control for advancing sustainability in buildings (I)

    NARCIS (Netherlands)

    Meacham, B.; Visscher, H.J.; Meijer, F.M.; Chan, C.; Chan, E.; Laubscher, J.; Neng Kwei Sung, J.; Dodds, B.; Serra, J.; Tenorio, J.A.; Echeverria, J.B.; Sanches-Ostiz, A.

    2014-01-01

    This session brings together policy-makers, government officials, researchers and others to present perspectives on how innovation in building regulation and control, such as performancebased approaches, are currently being used to advance sustainability concepts in buildings, and where and how we m

  14. Drug-resistant tuberculosis control in South Africa: scientific advances and health system strengthening are complementary.

    Science.gov (United States)

    Padayatchi, Nesri; Loveday, Marian; Naidu, Naressa

    2014-10-01

    We examine some aspects of the South African health system that have contributed to the current multi- and extensively drug-resistant tuberculosis (M(X)DR-TB) epidemic and identify opportunities for change and improvement. Implementation of several recent major scientific advances have the potential to accelerate the control of M(X)DR-TB, but health systems strengthening will be essential.

  15. Recent Advances in Substrate-Controlled Asymmetric Cyclization for Natural Product Synthesis

    Directory of Open Access Journals (Sweden)

    Jeyun Jo

    2017-06-01

    Full Text Available Asymmetric synthesis of naturally occurring diverse ring systems is an ongoing and challenging research topic. A large variety of remarkable reactions utilizing chiral substrates, auxiliaries, reagents, and catalysts have been intensively investigated. This review specifically describes recent advances in successful asymmetric cyclization reactions to generate cyclic architectures of various natural products in a substrate-controlled manner.

  16. Fieldcrest Cannon, Inc. Advanced Technical Preparation. Statistical Process Control (SPC). PRE-SPC I. Instructor Book.

    Science.gov (United States)

    Averitt, Sallie D.

    This instructor guide, which was developed for use in a manufacturing firm's advanced technical preparation program, contains the materials required to present a learning module that is designed to prepare trainees for the program's statistical process control module by improving their basic math skills and instructing them in basic calculator…

  17. Application of Advanced Process Control techniques to a pusher type reheating furnace

    Science.gov (United States)

    Zanoli, S. M.; Pepe, C.; Barboni, L.

    2015-11-01

    In this paper an Advanced Process Control system aimed at controlling and optimizing a pusher type reheating furnace located in an Italian steel plant is proposed. The designed controller replaced the previous control system, based on PID controllers manually conducted by process operators. A two-layer Model Predictive Control architecture has been adopted that, exploiting a chemical, physical and economic modelling of the process, overcomes the limitations of plant operators’ mental model and knowledge. In addition, an ad hoc decoupling strategy has been implemented, allowing the selection of the manipulated variables to be used for the control of each single process variable. Finally, in order to improve the system flexibility and resilience, the controller has been equipped with a supervision module. A profitable trade-off between conflicting specifications, e.g. safety, quality and production constraints, energy saving and pollution impact, has been guaranteed. Simulation tests and real plant results demonstrated the soundness and the reliability of the proposed system.

  18. Advanced numerical study of the three-axis magnetic attitude control and determination with uncertainties

    Science.gov (United States)

    Ivanov, D. S.; Ovchinnikov, M. Yu.; Penkov, V. I.; Roldugin, D. S.; Doronin, D. M.; Ovchinnikov, A. V.

    2017-03-01

    Attitude motion of a satellite equipped with magnetic control system is considered. System comprises of three magnetorquers and one three-axis magnetometer. Satellite is stabilized in orbital reference frame using PD controller and extended Kalman filter. Three-axis attitude is analyzed numerically with advanced assumptions: inertia tensor uncertainty, disturbances of unknown nature, magnetometer errors are taken into account. Stabilization and determination accuracy dependence on orbit inclination is studied.

  19. Energy Savings and Economics of Advanced Control Strategies for Packaged Heat Pumps

    Energy Technology Data Exchange (ETDEWEB)

    Wang, Weimin; Huang, Yunzhi; Katipamula, Srinivas

    2012-10-31

    Pacific Northwest National Laboratory (PNNL), with funding from the U.S. Department of Energy’s (DOE’s) Building Technologies Program (BTP), evaluated a number of control strategies for packaged cooling equipment that can be implemented in an advanced controller, which can be retrofit into existing packaged heat pump units to improve their operational efficiency. This report documents the results of that analysis.

  20. Flexible System Integration and Advanced Hierarchical Control Architectures in the Microgrid Research Laboratory of Aalborg University

    DEFF Research Database (Denmark)

    Meng, Lexuan; Hernández, Adriana Carolina Luna; Diaz, Enrique Rodriguez

    2016-01-01

    This paper presents the system integration and hierarchical control implementation in an inverter-based microgrid research laboratory (MGRL) in Aalborg University, Denmark. MGRL aims to provide a flexible experimental platform for comprehensive studies of microgrids. The structure of the laboratory...... system supervision, advanced secondary and tertiary management are realized in a microgrid central controller. The software and hardware schemes are described. Several example case studies are introduced and performed in order to achieve power quality regulation, energy management and flywheel energy...

  1. Advanced Design and Implementation of a Control Architecture for Long Range Autonomous Planetary Rovers

    Science.gov (United States)

    Martin-Alvarez, A.; Hayati, S.; Volpe, R.; Petras, R.

    1999-01-01

    An advanced design and implementation of a Control Architecture for Long Range Autonomous Planetary Rovers is presented using a hierarchical top-down task decomposition, and the common structure of each design is presented based on feedback control theory. Graphical programming is presented as a common intuitive language for the design when a large design team is composed of managers, architecture designers, engineers, programmers, and maintenance personnel. The whole design of the control architecture consists in the classic control concepts of cyclic data processing and event-driven reaction to achieve all the reasoning and behaviors needed. For this purpose, a commercial graphical tool is presented that includes the mentioned control capabilities. Messages queues are used for inter-communication among control functions, allowing Artificial Intelligence (AI) reasoning techniques based on queue manipulation. Experimental results show a highly autonomous control system running in real time on top the JPL micro-rover Rocky 7 controlling simultaneously several robotic devices. This paper validates the sinergy between Artificial Intelligence and classic control concepts in having in advanced Control Architecture for Long Range Autonomous Planetary Rovers.

  2. Test Platform for Advanced Digital Control of Brushless DC Motors (MSFC Center Director's Discretionary Fund)

    Science.gov (United States)

    Gwaltney, D. A.

    2002-01-01

    A FY 2001 Center Director's Discretionary Fund task to develop a test platform for the development, implementation. and evaluation of adaptive and other advanced control techniques for brushless DC (BLDC) motor-driven mechanisms is described. Important applications for BLDC motor-driven mechanisms are the translation of specimens in microgravity experiments and electromechanical actuation of nozzle and fuel valves in propulsion systems. Motor-driven aerocontrol surfaces are also being utilized in developmental X vehicles. The experimental test platform employs a linear translation stage that is mounted vertically and driven by a BLDC motor. Control approaches are implemented on a digital signal processor-based controller for real-time, closed-loop control of the stage carriage position. The goal of the effort is to explore the application of advanced control approaches that can enhance the performance of a motor-driven actuator over the performance obtained using linear control approaches with fixed gains. Adaptive controllers utilizing an exact model knowledge controller and a self-tuning controller are implemented and the control system performance is illustrated through the presentation of experimental results.

  3. Selective and sensitive colorimetric detection of stringent alarmone ppGpp with Fenton-like reagent.

    Science.gov (United States)

    Zheng, Lin Ling; Huang, Cheng Zhi

    2014-12-01

    Stringent alarmone, namely, guanosine 3'-diphosphate-5'-diphosphate (ppGpp), is a global regulator that plays a critical role in the survival, growth, metabolism, and many other vital processes of microorganisms. Because of its structural similarity to normal nucleotides, it is also a challenge for the selective and sensitive detection of ppGpp nowadays. Herein, we developed a colorimetric method for the selective detection of ppGpp by inhibiting the redox reaction between Fenton-like reagent (composed of Fe(3+) and H2O2) with 2,2'-azino-bis(3-ethylbenzthiazoline-6-sulfonic acid) (ABTS). Owing to the strong coordination affinity between ppGpp and Fe(3+), the chromogenic reaction between ABTS and Fenton-like reagent, occurred in aqueous medium at 37 °C and resulted in a bluish-green solution, which was inhibited with the addition of ppGpp. This phenomenon forms the basis for the colorimetric detection of ppGpp, with a detection limit of 0.19 μM and good selectivity for ppGpp over other nucleotides and anions. Furthermore, the results could be visualized by the naked eye, and the sensitivity of the naked-eye observation could even be further improved with the aid of the introduction of a background color.

  4. Ribosome•RelA structures reveal the mechanism of stringent response activation

    Science.gov (United States)

    Loveland, Anna B; Bah, Eugene; Madireddy, Rohini; Zhang, Ying; Brilot, Axel F; Grigorieff, Nikolaus; Korostelev, Andrei A

    2016-01-01

    Stringent response is a conserved bacterial stress response underlying virulence and antibiotic resistance. RelA/SpoT-homolog proteins synthesize transcriptional modulators (p)ppGpp, allowing bacteria to adapt to stress. RelA is activated during amino-acid starvation, when cognate deacyl-tRNA binds to the ribosomal A (aminoacyl-tRNA) site. We report four cryo-EM structures of E. coli RelA bound to the 70S ribosome, in the absence and presence of deacyl-tRNA accommodating in the 30S A site. The boomerang-shaped RelA with a wingspan of more than 100 Å wraps around the A/R (30S A-site/RelA-bound) tRNA. The CCA end of the A/R tRNA pins the central TGS domain against the 30S subunit, presenting the (p)ppGpp-synthetase domain near the 30S spur. The ribosome and A/R tRNA are captured in three conformations, revealing hitherto elusive states of tRNA engagement with the ribosomal decoding center. Decoding-center rearrangements are coupled with the step-wise 30S-subunit 'closure', providing insights into the dynamics of high-fidelity tRNA decoding. DOI: http://dx.doi.org/10.7554/eLife.17029.001 PMID:27434674

  5. Advancing Control for Shield Tunneling Machine by Backstepping Design with LuGre Friction Model

    Directory of Open Access Journals (Sweden)

    Haibo Xie

    2014-01-01

    Full Text Available Shield tunneling machine is widely applied for underground tunnel construction. The shield machine is a complex machine with large momentum and ultralow advancing speed. The working condition underground is rather complicated and unpredictable, and brings big trouble in controlling the advancing speed. This paper focused on the advancing motion control on desired tunnel axis. A three-state dynamic model was established with considering unknown front face earth pressure force and unknown friction force. LuGre friction model was introduced to describe the friction force. Backstepping design was then proposed to make tracking error converge to zero. To have a comparison study, controller without LuGre model was designed. Tracking simulations of speed regulations and simulations when front face earth pressure changed were carried out to show the transient performances of the proposed controller. The results indicated that the controller had good tracking performance even under changing geological conditions. Experiments of speed regulations were carried out to have validations of the controllers.

  6. The stringent response of Staphylococcus aureus and its impact on survival after phagocytosis through the induction of intracellular PSMs expression.

    Directory of Open Access Journals (Sweden)

    Tobias Geiger

    Full Text Available The stringent response is initiated by rapid (pppGpp synthesis, which leads to a profound reprogramming of gene expression in most bacteria. The stringent phenotype seems to be species specific and may be mediated by fundamentally different molecular mechanisms. In Staphylococcus aureus, (pppGpp synthesis upon amino acid deprivation is achieved through the synthase domain of the bifunctional enzyme RSH (RelA/SpoT homolog. In several firmicutes, a direct link between stringent response and the CodY regulon was proposed. Wild-type strain HG001, rsh(Syn, codY and rsh(Syn, codY double mutants were analyzed by transcriptome analysis to delineate different consequences of RSH-dependent (pppGpp synthesis after induction of the stringent response by amino-acid deprivation. Under these conditions genes coding for major components of the protein synthesis machinery and nucleotide metabolism were down-regulated only in rsh positive strains. Genes which became activated upon (pppGpp induction are mostly regulated indirectly via de-repression of the GTP-responsive repressor CodY. Only seven genes, including those coding for the cytotoxic phenol-soluble modulins (PSMs, were found to be up-regulated via RSH independently of CodY. qtRT-PCR analyses of hallmark genes of the stringent response indicate that an RSH activating stringent condition is induced after uptake of S. aureus in human polymorphonuclear neutrophils (PMNs. The RSH activity in turn is crucial for intracellular expression of psms. Accordingly, rsh(Syn and rsh(Syn, codY mutants were less able to survive after phagocytosis similar to psm mutants. Intraphagosomal induction of psmα1-4 and/or psmβ1,2 could complement the survival of the rsh(Syn mutant. Thus, an active RSH synthase is required for intracellular psm expression which contributes to survival after phagocytosis.

  7. SpaceWire- Based Control System Architecture for the Lightweight Advanced Robotic Arm Demonstrator [LARAD

    Science.gov (United States)

    Rucinski, Marek; Coates, Adam; Montano, Giuseppe; Allouis, Elie; Jameux, David

    2015-09-01

    The Lightweight Advanced Robotic Arm Demonstrator (LARAD) is a state-of-the-art, two-meter long robotic arm for planetary surface exploration currently being developed by a UK consortium led by Airbus Defence and Space Ltd under contract to the UK Space Agency (CREST-2 programme). LARAD has a modular design, which allows for experimentation with different electronics and control software. The control system architecture includes the on-board computer, control software and firmware, and the communication infrastructure (e.g. data links, switches) connecting on-board computer(s), sensors, actuators and the end-effector. The purpose of the control system is to operate the arm according to pre-defined performance requirements, monitoring its behaviour in real-time and performing safing/recovery actions in case of faults. This paper reports on the results of a recent study about the feasibility of the development and integration of a novel control system architecture for LARAD fully based on the SpaceWire protocol. The current control system architecture is based on the combination of two communication protocols, Ethernet and CAN. The new SpaceWire-based control system will allow for improved monitoring and telecommanding performance thanks to higher communication data rate, allowing for the adoption of advanced control schemes, potentially based on multiple vision sensors, and for the handling of sophisticated end-effectors that require fine control, such as science payloads or robotic hands.

  8. PERFORMANCE STUDIES OF INTEGRATED FUZZY LOGIC CONTROLLER FOR BRUSHLESS DC MOTOR DRIVES USING ADVANCED SIMULATION MODEL

    Directory of Open Access Journals (Sweden)

    C. Subba Rami Reddy

    2011-07-01

    Full Text Available This paper introduces an Integrated fuzzy logic controller (IFLC for brushless dc (BLDC motor drives using advanced simulation model and presents a comparative study of performances of PID controller and IFLC. The dynamic characteristics of speed and torque are effectively monitored and analyzed using the proposed model. The aim of IFLC is to obtain improved performance in terms of disturbance rejection or parameter variation than obtained using PID controller. The IFLC is constructed by using Fuzzy logic controller (FLC and PID controller. A performance comparison of the controllers is also given based on the integral of the absolute value of the error (IAE, the integral of the squared error (ISE, the integral of the time-weighted absolute error (ITAE and the integral of the time-weighted squared error (ITSE. The results show the effectiveness of the proposed controller.

  9. Neural network setpoint control of an advanced test reactor experiment loop simulation

    Energy Technology Data Exchange (ETDEWEB)

    Cordes, G.A.; Bryan, S.R.; Powell, R.H.; Chick, D.R.

    1990-09-01

    This report describes the design, implementation, and application of artificial neural networks to achieve temperature and flow rate control for a simulation of a typical experiment loop in the Advanced Test Reactor (ATR) located at the Idaho National Engineering Laboratory (INEL). The goal of the project was to research multivariate, nonlinear control using neural networks. A loop simulation code was adapted for the project and used to create a training set and test the neural network controller for comparison with the existing loop controllers. The results for three neural network designs are documented and compared with existing loop controller action. The neural network was shown to be as accurate at loop control as the classical controllers in the operating region represented by the training set. 9 refs., 28 figs., 2 tabs.

  10. Nonlinear Output Feedback Control of Underwater Vehicle Propellers using Advance Speed Feedback

    DEFF Research Database (Denmark)

    Fossen, T.I.; Blanke, M.

    1999-01-01

    More accurate propeller shaft speed controllers can be designed by using nonlinear control theory. In this paper, an output feedback controller reconstructing the advance speed (speed of water going into the propeller) from vehicle speed measurements is derived. For this purpose a three-state model...... of propeller shaft speed, forward (surge) speed of the vehicle and axial inlet flow of the propeller is applied. A nonlinear observer in combination with an output feedback integral controller are derived by applying Lyapunov stability theory and exponential stability is proven. The output feedback controller...... minimizes thruster losses due to variations in propeller axial inlet flow which is a major problem when applying conventional vehicle-propeller control systems. The proposed controller is simulated for an underwater vehicle equipped with a single propeller. From the simulations it can be concluded...

  11. The effects of speech controls on performance in advanced helicopters in a double stimulation paradigm

    Science.gov (United States)

    Bortolussi, Michael R.; Vidulich, Michael A.

    1991-01-01

    The potential benefit of speech as a control modality has been investigated with mixed results. Earlier studies suggests that speech controls can reduce the potential of manual control overloads and improve time-sharing performance. However, these benefits were not without costs. Pilots reported higher workload levels associated with the use of speech controls. To further investigate these previous findings, an experiment was conducted in a simulation of an advanced single-pilot, scout/attack helicopter at NASA-Ames' ICAB (interchangeable cab) facility. Objective performance data suggested that speech control modality was effective in reducing interference of discrete, time-shared responses during continuous flight control activity. Subjective ratings, however, indicated that the speech control modality increased workload. Post-flight debriefing indicated that these results were mainly due to the increased effort to speak precisely to a less than perfect voice recognition system.

  12. Dynamics and Control of Orbiting Space Structures NASA Advanced Design Program (ADP)

    Science.gov (United States)

    Cruse, T. A.

    1996-01-01

    The report summarizes the advanced design program in the mechanical engineering department at Vanderbilt University for the academic years 1994-1995 and 1995-1996. Approximately 100 students participated in the two years of the subject grant funding. The NASA-oriented design projects that were selected included lightweight hydrogen propellant tank for the reusable launch vehicle, a thermal barrier coating test facility, a piezoelectric motor for space antenna control, and a lightweight satellite for automated materials processing. The NASA supported advanced design program (ADP) has been a success and a number of graduates are working in aerospace and are doing design.

  13. Quality Control Review of BDO USA, LLP FY 2013 Single Audit of Advanced Technology International

    Science.gov (United States)

    2014-11-03

    foundation for uniform audit requirements of non-Federal entities administering Federal awards. Entities that expend $500,000 or more in a year are subject...Report No. DODIG-2015-027 N o v e m b e r 3 , 2 0 1 4 Quality Control Review of BDO USA, LLP FY 2013 Single Audit of Advanced Technology...Single Audit of Advanced Technology International 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) 5d. PROJECT NUMBER 5e

  14. Development of a Power Electronics Controller for the Advanced Stirling Radioisotope Generator

    Science.gov (United States)

    Leland, Douglas K.; Priest, Joel F.; Keiter, Douglas E.; Schreiber, Jeffrey G.

    2008-01-01

    Under a U.S. Department of Energy program for radioisotope power systems, Lockheed Martin is developing an Engineering Unit of the Advanced Stirling Radioisotope Generator (ASRG). This is an advanced version of the previously reported SRG110 generator. The ASRG uses Advanced Stirling Convertors (ASCs) developed by Sunpower Incorporated under a NASA Research Announcement contract. The ASRG makes use of a Stirling controller based on power electronics that eliminates the tuning capacitors. The power electronics controller synchronizes dual-opposed convertors and maintains a fixed frequency operating point. The controller is single-fault tolerant and uses high-frequency pulse width modulation to create the sinusoidal currents that are nearly in phase with the piston velocity, eliminating the need for large series tuning capacitors. Sunpower supports this effort through an extension of their controller development intended for other applications. Glenn Research Center (GRC) supports this effort through system dynamic modeling, analysis and test support. The ASRG design arrived at a new baseline based on a system-level trade study and extensive feedback from mission planners on the necessity of single-fault tolerance. This paper presents the baseline design with an emphasis on the power electronics controller detailed design concept that will meet space mission requirements including single fault tolerance.

  15. Advanced Controls and Communications for Demand Response andEnergy Efficiency in Commercial Buildings

    Energy Technology Data Exchange (ETDEWEB)

    Kiliccote, Sila; Piette, Mary Ann; Hansen, David

    2006-01-17

    Commercial buildings account for a large portion of summer peak demand. Research results show that there is significant potential to reduce peak demand in commercial buildings through advanced control technologies and strategies. However, a better understanding of commercial building's contribution to peak demand and the use of energy management and control systems is required to develop this demand response resource to its full potential. This paper discusses recent research results and new opportunities for advanced building control systems to provide demand response (DR) to improve electricity markets and reduce electric grid problems. The main focus of this paper is the role of new and existing control systems for HVAC and lighting in commercial buildings. A demand-side management framework from building operations perspective with three main features: daily energy efficiency, daily peak load management and event driven, dynamic demand response is presented. A general description of DR, its benefits, and nationwide potential in commercial buildings is outlined. Case studies involving energy management and control systems and DR savings opportunities are presented. The paper also describes results from three years of research in California to automate DR in buildings. Case study results and research on advanced buildings systems in New York are also presented.

  16. A framework for advanced methods of control of human-induced vibrations

    Science.gov (United States)

    Reynolds, Paul

    2012-04-01

    The vibration serviceability of civil engineering structures under human dynamic excitation is becoming ever more critical with the design and redevelopment of structures with reduced mass, stiffness and damping. A large number of problems have been reported in floors, footbridges, sports stadia, staircases and other structures. Unfortunately, the range of options available to fix such problems are very limited and are primarily limited to structural modification or the implementation of passive vibration control measures, such as tuned mass dampers. This paper presents the initial development of a new framework for advanced methods of control of humaninduced vibrations in civil engineering structures. This framework includes both existing passive methods of vibration control and more advanced active, semi-active and hybrid control techniques, which may be further developed as practical solutions for these problems. Through the use of this framework, rational decisions as to the most appropriate technologies for particular human vibration problems may be made and pursued further. This framework is also intended to be used in the design of new civil engineering structures, where advanced control technologies may be used both to increase the achievable slenderness and to reduce the amount of construction materials used and hence their embodied energy. This will be an ever more important consideration with the current drive for structures with reduced environmental impact.

  17. Advanced Adaptive Particle Swarm Optimization based SVC Controller for Power System Stability

    Directory of Open Access Journals (Sweden)

    Poonam Singhal

    2014-12-01

    Full Text Available The interconnected systems is continually increasing in size and extending over whole geographical regions, it is becoming increasingly more difficult to maintain synchronism between various parts of the power system. This paper work presents an advanced adaptive Particle swarm optimization technique to optimize the SVC controller parameters for enhancement of the steady state stability & overcoming the premature convergence & stagnation problems as in basic PSO algorithm & Particle swarm optimization with shrinkage factor & inertia weight approach (PSO-SFIWA. In this paper SMIB system along with PID damped SVC controller is considered for study. The generator speed deviation is used as an auxiliary signal to SVC, to generate the desired damping. This controller improves the dynamic performance of power system by reducing the steady-state error. The controller parameters are optimized using basic PSO, PSO-SFIWA & Advanced Adaptive PSO. Computational results show that Advanced Adaptive based SVC controller is able to find better quality solution as compare to conventional PSO & PSO-SFIWA Techniques.

  18. Advanced Control of Wind Electric Pumping System for Isolated Areas Application

    Directory of Open Access Journals (Sweden)

    Mohamed Barara

    2014-12-01

    Full Text Available The supply water in remote areas of windy region is one of most attractive application of wind energy conversion .This paper proposes an advanced controller suitable for wind-electric pump in isolated applications in order to have a desired debit from variation of reference speed of the pump also the control scheme of DC voltage of SIEG for feed the pump are presented under step change in wind speed. The simulation results showed a good performance of the global proposed control system.

  19. Advanced electric drives analysis, control, and modeling using MATLAB/Simulink

    CERN Document Server

    Mohan, Ned

    2014-01-01

    Advanced Electric Drives utilizes a physics-based approach to explain the fundamental concepts of modern electric drive control and its operation under dynamic conditions. Gives readers a "physical" picture of electric machines and drives without resorting to mathematical transformations for easy visualization Confirms the physics-based analysis of electric drives mathematically Provides readers with an analysis of electric machines in a way that can be easily interfaced to common power electronic converters and controlled using any control scheme Makes the MATLAB/Simulink files used in exampl

  20. Structural basis for the function of stringent starvation protein a as a transcription factor.

    Science.gov (United States)

    Hansen, Anne-Marie; Gu, Yijun; Li, Mi; Andrykovitch, Michelle; Waugh, David S; Jin, Ding Jun; Ji, Xinhua

    2005-04-29

    Stringent starvation protein A (SspA) of Escherichia coli is an RNA polymerase-associated transcriptional activator for the lytic development of phage P1 and is essential for stationary phase-induced acid tolerance of E. coli. We report the crystal structure of Yersinia pestis SspA, which is 83% identical to E. coli SspA in amino acid sequence and is functionally complementary in supporting the lytic growth of phage P1 and acid resistance of an E. coli sspA mutant. The structure reveals that SspA assumes the characteristic fold of glutathione S-transferase (GST). However, SspA lacks GST activity and does not bind glutathione. Three regions of SspA are flexible, the N and C termini and the alpha2-helix. The structure also reveals a conserved surface-exposed pocket composed of residues from a loop between helices alpha3 and alpha4. The functional roles of these structural features were investigated by assessing the ability of deletion and site-directed mutants to confer acid resistance of E. coli and to activate transcription from a phage P1 late promoter, thereby supporting the lytic growth of phage P1. The results indicate that the flexible regions are not critical for SspA function, whereas the surface pocket is important for both transcriptional activation of the phage P1 late promoter and acid resistance of E. coli. The size, shape, and property of the pocket suggest that it mediates protein-protein interactions. SspA orthologs from Y. pestis, Vibrio cholerae, and Pseudomonas aeruginosa are all functional in acid resistance of E. coli, whereas only Y. pestis SspA supports phage P1 growth.

  1. Protein:Ligand binding free energies: A stringent test for computational protein design.

    Science.gov (United States)

    Druart, Karen; Palmai, Zoltan; Omarjee, Eyaz; Simonson, Thomas

    2016-02-01

    A computational protein design method is extended to allow Monte Carlo simulations where two ligands are titrated into a protein binding pocket, yielding binding free energy differences. These provide a stringent test of the physical model, including the energy surface and sidechain rotamer definition. As a test, we consider tyrosyl-tRNA synthetase (TyrRS), which has been extensively redesigned experimentally. We consider its specificity for its substrate l-tyrosine (l-Tyr), compared to the analogs d-Tyr, p-acetyl-, and p-azido-phenylalanine (ac-Phe, az-Phe). We simulate l- and d-Tyr binding to TyrRS and six mutants, and compare the structures and binding free energies to a more rigorous "MD/GBSA" procedure: molecular dynamics with explicit solvent for structures and a Generalized Born + Surface Area model for binding free energies. Next, we consider l-Tyr, ac- and az-Phe binding to six other TyrRS variants. The titration results are sensitive to the precise rotamer definition, which involves a short energy minimization for each sidechain pair to help relax bad contacts induced by the discrete rotamer set. However, when designed mutant structures are rescored with a standard GBSA energy model, results agree well with the more rigorous MD/GBSA. As a third test, we redesign three amino acid positions in the substrate coordination sphere, with either l-Tyr or d-Tyr as the ligand. For two, we obtain good agreement with experiment, recovering the wildtype residue when l-Tyr is the ligand and a d-Tyr specific mutant when d-Tyr is the ligand. For the third, we recover His with either ligand, instead of wildtype Gln.

  2. On the connections and differences among three mean-field approximations: a stringent test.

    Science.gov (United States)

    Yi, Shasha; Pan, Cong; Hu, Liming; Hu, Zhonghan

    2017-07-19

    This letter attempts to clarify the meaning of three closely related mean-field approximations: random phase approximation (RPA), local molecular field (LMF) approximation, and symmetry-preserving mean-field (SPMF) approximation, and their use of reliability and validity in the field of theory and simulation of liquids when the long-ranged component of the intermolecular interaction plays an important role in determining density fluctuations and correlations. The RPA in the framework of classical density functional theory (DFT) neglects the higher order correlations in the bulk and directly applies the long-ranged part of the potential to correct the pair direct correlation function of the short-ranged system while the LMF approach introduces a nonuniform mimic system under a reconstructed static external potential that accounts for the average effect arising from the long-ranged component of the interaction. Furthermore, the SPMF approximation takes the viewpoint of LMF but instead instantaneously averages the long-ranged component of the potential over the degrees of freedom in the direction with preserved symmetry. The formal connections and the particular differences of the viewpoint among the three approximations are explained and their performances in producing structural properties of liquids are stringently tested using an exactly solvable model. We demonstrate that the RPA treatment often yields uncontrolled poor results for pair distribution functions of the bulk system. On the other hand, the LMF theory produces quite reasonably structural correlations when the pair distribution in the bulk is converted to the singlet particle distribution in the nonuniform system. It turns out that the SPMF approach outperforms the other two at all densities and under extreme conditions where the long-ranged component significantly contributes to the structural correlations.

  3. Adaptation to fluctuating temperatures in an RNA virus is driven by the most stringent selective pressure.

    Directory of Open Access Journals (Sweden)

    María Arribas

    Full Text Available The frequency of change in the selective pressures is one of the main factors driving evolution. It is generally accepted that constant environments select specialist organisms whereas changing environments favour generalists. The particular outcome achieved in either case also depends on the relative strength of the selective pressures and on the fitness costs of mutations across environments. RNA viruses are characterized by their high genetic diversity, which provides fast adaptation to environmental changes and helps them evade most antiviral treatments. Therefore, the study of the adaptive possibilities of RNA viruses is highly relevant for both basic and applied research. In this study we have evolved an RNA virus, the bacteriophage Qβ, under three different temperatures that either were kept constant or alternated periodically. The populations obtained were analyzed at the phenotypic and the genotypic level to characterize the evolutionary process followed by the virus in each case and the amount of convergent genetic changes attained. Finally, we also investigated the influence of the pre-existent genetic diversity on adaptation to high temperature. The main conclusions that arise from our results are: i under periodically changing temperature conditions, evolution of bacteriophage Qβ is driven by the most stringent selective pressure, ii there is a high degree of evolutionary convergence between replicated populations and also among populations evolved at different temperatures, iii there are mutations specific of a particular condition, and iv adaptation to high temperatures in populations differing in their pre-existent genetic diversity takes place through the selection of a common set of mutations.

  4. Pro Telerik ASPNET and Silverlight Controls Master Telerik Controls for Advanced ASPNET and Silverlight Projects

    CERN Document Server

    Paz, J Guay

    2010-01-01

    This book provides a complete guide to implementing Telerik's range of ASP.NET and Silverlight controls. Telerik controls are invaluable for ASP.NET and Silverlight developers because they provide a vast array of rich controls targeted for the presentation layer of web applications. Telerik offers you solutions for the reports, grids, charts, and text-editing controls that you need but don't want to build from scratch yourself - the options are endless for increasing the functionality of any of your web solutions. What you'll learn * Understand how to integrate the standard Telerik controls in

  5. Advanced Interval Type-2 Fuzzy Sliding Mode Control for Robot Manipulator.

    Science.gov (United States)

    Hwang, Ji-Hwan; Kang, Young-Chang; Park, Jong-Wook; Kim, Dong W

    2017-01-01

    In this paper, advanced interval type-2 fuzzy sliding mode control (AIT2FSMC) for robot manipulator is proposed. The proposed AIT2FSMC is a combination of interval type-2 fuzzy system and sliding mode control. For resembling a feedback linearization (FL) control law, interval type-2 fuzzy system is designed. For compensating the approximation error between the FL control law and interval type-2 fuzzy system, sliding mode controller is designed, respectively. The tuning algorithms are derived in the sense of Lyapunov stability theorem. Two-link rigid robot manipulator with nonlinearity is used to test and the simulation results are presented to show the effectiveness of the proposed method that can control unknown system well.

  6. Experiments in advanced control concepts for space robotics - An overview of the Stanford Aerospace Robotics Laboratory

    Science.gov (United States)

    Hollars, M. G.; Cannon, R. H., Jr.; Alexander, H. L.; Morse, D. F.

    1987-01-01

    The Stanford University Aerospace Robotics Laboratory is actively developing and experimentally testing advanced robot control strategies for space robotic applications. Early experiments focused on control of very lightweight one-link manipulators and other flexible structures. The results are being extended to position and force control of mini-manipulators attached to flexible manipulators and multilink manipulators with flexible drive trains. Experimental results show that end-point sensing and careful dynamic modeling or adaptive control are key to the success of these control strategies. Free-flying space robot simulators that operate on an air cushion table have been built to test control strategies in which the dynamics of the base of the robot and the payload are important.

  7. Advanced Interval Type-2 Fuzzy Sliding Mode Control for Robot Manipulator

    Science.gov (United States)

    Hwang, Ji-Hwan; Kang, Young-Chang

    2017-01-01

    In this paper, advanced interval type-2 fuzzy sliding mode control (AIT2FSMC) for robot manipulator is proposed. The proposed AIT2FSMC is a combination of interval type-2 fuzzy system and sliding mode control. For resembling a feedback linearization (FL) control law, interval type-2 fuzzy system is designed. For compensating the approximation error between the FL control law and interval type-2 fuzzy system, sliding mode controller is designed, respectively. The tuning algorithms are derived in the sense of Lyapunov stability theorem. Two-link rigid robot manipulator with nonlinearity is used to test and the simulation results are presented to show the effectiveness of the proposed method that can control unknown system well.

  8. Status of the advanced photon source and its accelerator control system

    Science.gov (United States)

    McDowell, W.; Knott, M.; Kraimer, M.

    1994-12-01

    This paper presents the current status of the Advanced Photon Source (APS), its control system and the Experimental Physics and Industrial Control System (EPICS) tools being used to implement this control system. The status of the physical plant and each of the accelerators as well as detailed descriptions of the software tools used to build the accelerator control system are presented. The control system uses high-performance graphic workstations and the X-Windows graphical user interface (GUI) at the operator interface level. It connects to VME/VXI-based microprocessors at the field level, using TCP/IP protocols over high-performance networks. This strategy assures the flexibility and expansibility of the control system. A defined interface between the system components will allow the system to evolve with the direct addition of future, improved equipment and new capabilities.

  9. Identification of stringent response-related and potential serological proteins released from Bacillus anthracis overexpressing the RelA/SpoT homolog, Rsh Bant.

    Science.gov (United States)

    Kim, Se Kye; Park, Moon Kyoo; Kim, Sang Hoon; Oh, Kwang Gun; Jung, Kyoung Hwa; Hong, Chong-Hae; Yoon, Jang W; Chai, Young Gyu

    2014-10-01

    RelA and SpoT synthesize ppGpp, a key effector molecule that facilitates the adaptation of bacteria to nutrient starvation and other stresses, known as the stringent response. To investigate the role of Rsh Bant , a putative RelA/SpoT homolog (encoded by BAS4302) in Bacillus anthracis, we examined the alteration of the secretome profiles after the overexpression of a functional His-Rsh Bant protein in the B. anthracis strain Sterne at the stationary growth phase. In the ppGpp-deficient E. coli mutant strain CF1693, overexpression of Rsh Bant restored a ppGpp-dependent growth defect on minimal glucose media. The secretome profiles obtained using a two-dimensional electrophoresis (2-DE) analysis were altered by overexpression of Rsh Bant in B. anthracis. Among the 66 protein spots differentially expressed >1.5-fold, the 29 proteins were abundant for further identification using matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS). Functional categorization of those proteins implicated their involvement in various biological activities. Taken together, our results imply that overexpression of a functional His-Rsh Bant can lead to the increased levels of intracellular ppGpp in B. anthracis, resulting in the significant changes in its secretome profiling. The stringent response-controlled proteins identified are likely useful as potential targets for serodiagnostic applications.

  10. Operational Strategy of CBPs for load balancing of Operators in Advanced Main Control Room

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Seunghwan; Kim, Yochan; Jung, Wondea [Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of)

    2014-05-15

    With the using of a computer-based control room in an APR1400 (Advanced Pressurized Reactor-1400), the operators' behaviors in the main control room had changed. However, though the working environment of operators has been changed a great deal, digitalized interfaces can also change the cognitive tasks or activities of operators. First, a shift supervisor (SS) can confirm/check the conduction of the procedures and the execution of actions of board operators (BOs) while confirming directly the operation variables without relying on the BOs. Second, all operators added to their work the use of a new CBP and Soft Controls, increasing their procedural workload. New operational control strategies of CBPs are necessary for load balancing of operator's task load in APR1400. In this paper, we compared the workloads of operators in an APR1400 who work with two different usages of the CBP. They are SS oriented usage and SS-BO collaborative usage. In this research, we evaluated the workloads of operators in an advanced main control room by the COCOA method. Two types of CBP usages were defined and the effects of these usages on the workloads were investigated. The obtained results showed that the workloads between operators in a control room can be balanced according to the CBP usages by assigning control authority to the operators.

  11. Modeling Human Error Mechanism for Soft Control in Advanced Control Rooms (ACRs)

    Energy Technology Data Exchange (ETDEWEB)

    Aljneibi, Hanan Salah Ali [Khalifa Univ., Abu Dhabi (United Arab Emirates); Ha, Jun Su; Kang, Seongkeun; Seong, Poong Hyun [KAIST, Daejeon (Korea, Republic of)

    2015-10-15

    To achieve the switch from conventional analog-based design to digital design in ACRs, a large number of manual operating controls and switches have to be replaced by a few common multi-function devices which is called soft control system. The soft controls in APR-1400 ACRs are classified into safety-grade and non-safety-grade soft controls; each was designed using different and independent input devices in ACRs. The operations using soft controls require operators to perform new tasks which were not necessary in conventional controls such as navigating computerized displays to monitor plant information and control devices. These kinds of computerized displays and soft controls may make operations more convenient but they might cause new types of human error. In this study the human error mechanism during the soft controls is studied and modeled to be used for analysis and enhancement of human performance (or human errors) during NPP operation. The developed model would contribute to a lot of applications to improve human performance (or reduce human errors), HMI designs, and operators' training program in ACRs. The developed model of human error mechanism for the soft control is based on assumptions that a human operator has certain amount of capacity in cognitive resources and if resources required by operating tasks are greater than resources invested by the operator, human error (or poor human performance) is likely to occur (especially in 'slip'); good HMI (Human-machine Interface) design decreases the required resources; operator's skillfulness decreases the required resources; and high vigilance increases the invested resources. In this study the human error mechanism during the soft controls is studied and modeled to be used for analysis and enhancement of human performance (or reduction of human errors) during NPP operation.

  12. Cholera toxin production during anaerobic trimethylamine N-oxide respiration is mediated by stringent response in Vibrio cholerae.

    Science.gov (United States)

    Oh, Young Taek; Park, Yongjin; Yoon, Mi Young; Bari, Wasimul; Go, Junhyeok; Min, Kyung Bae; Raskin, David M; Lee, Kang-Mu; Yoon, Sang Sun

    2014-05-09

    As a facultative anaerobe, Vibrio cholerae can grow by anaerobic respiration. Production of cholera toxin (CT), a major virulence factor of V. cholerae, is highly promoted during anaerobic growth using trimethylamine N-oxide (TMAO) as an alternative electron acceptor. Here, we investigated the molecular mechanisms of TMAO-stimulated CT production and uncovered the crucial involvement of stringent response in this process. V. cholerae 7th pandemic strain N16961 produced a significantly elevated level of ppGpp, the bacterial stringent response alarmone, during anaerobic TMAO respiration. Bacterial viability was impaired, and DNA replication was also affected under the same growth condition, further suggesting that stringent response is induced. A ΔrelA ΔspoT ppGpp overproducer strain produced an enhanced level of CT, whereas anaerobic growth via TMAO respiration was severely inhibited. In contrast, a ppGpp-null strain (ΔrelA ΔspoT ΔrelV) grew substantially better, but produced no CT, suggesting that CT production and bacterial growth are inversely regulated in response to ppGpp accumulation. Bacterial capability to produce CT was completely lost when the dksA gene, which encodes a protein that works cooperatively with ppGpp, was deleted. In the ΔdksA mutant, stringent response growth inhibition was alleviated, further supporting the inverse regulation of CT production and anaerobic growth. In vivo virulence of ΔrelA ΔspoT ΔrelV or ΔdksA mutants was significantly attenuated. The ΔrelA ΔspoT mutant maintained virulence when infected with exogenous TMAO despite its defective growth. Together, our results reveal that stringent response is activated under TMAO-stimulated anaerobic growth, and it regulates CT production in a growth-dependent manner in V. cholerae.

  13. Dynamics and Control of Switched Electronic Systems Advanced Perspectives for Modeling, Simulation and Control of Power Converters

    CERN Document Server

    Iannelli, Luigi

    2012-01-01

    The increased efficiency and quality constraints imposed on electrical energy systems have inspired a renewed research interest in the study of formal approaches to the analysis and control of power electronics converters. Switched systems represent a useful framework for modeling these converters and the peculiarities of their operating conditions and control goals justify the specific classification of “switched electronic systems”. Indeed, idealized switched models of power converters introduce problems not commonly encountered when analyzing generic switched models or non-switched electrical networks. In that sense the analysis of switched electronic systems represents a source for new ideas and benchmarks for switched and hybrid systems generally. Dynamics and Control of Switched Electronic Systems draws on the expertise of an international group of expert contributors to give an overview of recent advances in the modeling, simulation and control of switched electronic systems. The reader is provided...

  14. Profile control of advanced tokamak plasmas in view of continuous operation

    Science.gov (United States)

    Mazon, D.

    2015-07-01

    The concept of the tokamak is a very good candidate to lead to a fusion reactor. In fact, certain regimes of functioning allow today the tokamaks to attain performances close to those requested by a reactor. Among the various scenarios of functioning nowadays considered for the reactor option, certain named 'advanced scenarios' are characterized by an improvement of the stability and confinement in the plasma core, as well as by a modification of the current profile, notably thank to an auto-generated 'bootstrap' current. The general frame of this paper treats the perspective of a real-time control of advanced regimes. Concrete examples will underline the impact of diagnostics on the identification of plasma models, from which the control algorithms are constructed. Several preliminary attempts will be described.

  15. Proposing a new advanced control technique for micro hydro power plants

    Energy Technology Data Exchange (ETDEWEB)

    Hanmandlu, M.; Goyal, Himani [Department of Electrical Engineering, Indian Institute of Technology, Hauz Khas, New Delhi 110016 (India)

    2008-05-15

    Micro hydropower plants are emerging as a major renewable energy resource today as they do not encounter the problems of population displacement and environmental problems associated with the large hydro power plants. However, they require control systems to limit the huge variation in input flows expected in rivulets over which these are established to produce a constant power supply. This paper proposes an electric servomotor as a governor for a micro hydro power plant especially those plants that are operated in isolated mode. An advanced controller is developed combining four control schemes for the control of the governor following the concept that the control action can be split up into linear and non-linear parts. The linear part of this controller contains an adaptive fast transversal filter (FTF) algorithm and normalized LMS (nLMS) algorithm. The non-linear part of the controller incorporates Fuzzy PI and a neural network. The concept behind splitting the control action is reasoned out and the conditions for stability of the controller are proved. The new controller has a superior performance compared to other control schemes. (author)

  16. DYNAMIC MODELLING AND ADVANCED PREDICTIVE CONTROL OF A CONTINUOUS PROCESS OF ENZYME PURIFICATION

    Directory of Open Access Journals (Sweden)

    Dechechi E.C.

    1997-01-01

    Full Text Available A dynamic mathematical model, simulation and computer control of a Continuous Affinity Recycle Extraction (CARE process, a protein purification technique based on protein adsorption on solid-phase adsorbents is described in this work. This process, consisting of three reactors, is a multivariable process with considerable time delay in the on-line analyses of the controlled variable. An advanced predictive control configuration, specifically the Dynamic Matrix Control (DMC, was applied. The DMC algorithm was applied in process schemes where the aim was to maintain constant the enzyme concentration in the outlet of the third reactor. The performance of the DMC controller was analyzed in the feed-flow disturbances and the results are presented.

  17. Advanced flow measurement and active flow control of aircraft with MEMS

    Institute of Scientific and Technical Information of China (English)

    Jiang Chengyu; Deng Jinjun; Ma Binghe; Yuan Weizheng

    2012-01-01

    Advanced flow measurement and active flow control need the development of new type devices and systems. Micro-electro-mechanical systems (MEMS) technologies become the important and feasible approach for micro transducers fabrication. This paper introduces research works of MEMS/NEMS Lab in flow measurement sensors and active flow control actuators. Micro sensors include the flexible thermal sensor array, capacitive shear stress sensor and high sensitivity pressure sensor. Micro actuators are the balloon actuator and synthetic jet actuator respectively. Through wind tunnel test, these micro transducers achieve the goals of shear stress and pressure distribution measurement, boundary layer separation control, lift enhancement, etc. And unmanned aerial vehicle (UAV) flight test verifies the ability of maneuver control of micro actuator. In the future work, micro sensor and actuator can be combined into a closed-loop control system to construct aerodynamic smart skin system for aircraft.

  18. Advanced Sensors and Controls for Building Applications: Market Assessment and Potential R&D Pathways

    Energy Technology Data Exchange (ETDEWEB)

    Brambley, Michael R.; Haves, Philip; McDonald, Sean C.; Torcellini, Paul; Hansen, David G.; Holmberg, David; Roth, Kurt

    2005-04-13

    Significant energy savings can be achieved in commercial building operation, along with increased comfort and control for occupants, through the implementation of advanced technologies. This document provides a market assessment of existing building sensors and controls and presents a range of technology pathways (R&D options) for pursuing advanced sensors and building control strategies. This paper is actually a synthesis of five other white papers: the first describes the market assessment including estimates of market potential and energy savings for sensors and control strategies currently on the market as well as a discussion of market barriers to these technologies. The other four cover technology pathways: (1) current applications and strategies for new applications, (2) sensors and controls, (3) networking, security, and protocols and standards, and (4) automated diagnostics, performance monitoring, commissioning, optimal control and tools. Each technology pathway chapter gives an overview of the technology or application. This is followed by a discussion of needs and the current status of the technology. Finally, a series of research topics is proposed.

  19. Glycated albumin is the preferred marker for assessing glycaemic control in advanced chronic kidney disease.

    Science.gov (United States)

    Vos, Frederiek E; Schollum, John B; Walker, Robert J

    2011-12-01

    Diabetic nephropathy is the most common aetiology of end-stage kidney disease (ESKD). Strict glycaemic control reduces the development and progression of diabetes-related complications, and there is evidence that improved metabolic control improves outcomes in diabetic subjects with advanced chronic kidney disease (CKD). Glycaemic control in people with kidney disease is complex. Changes in glucose and insulin homeostasis may occur as a consequence of loss of kidney function and dialysis. The reliability of measures of long-term glycaemic control is affected by CKD and the accuracy of glycated haemoglobin (HbA1c) in the setting of CKD and ESKD is questioned. Despite the altered character of diabetes in CKD, current guidelines for diabetes management are not specifically adjusted to this patient group. The validity of indicators of longer term glycaemic control has been the focus of increased recent research. This review discusses the current understanding of commonly used indicators of metabolic control (HbA1c, fructosamine, glycated albumin) in the setting of advanced CKD (Stages 4 and 5, glomerular filtration rate <30 mL/min/1.73m(2)).

  20. Analisis Kinerja Metode Power Control untuk Manajemen Interferensi Sistem Komunikasi Uplink LTE-Advanced dengan Femtocell

    OpenAIRE

    Safirina Febryanti; Gamantyo Hendrantoro; Devy Kuswidiastuti

    2013-01-01

    Teknologi LTE-Advanced menghadirkan fitur baru bernama femtocell atau disebut juga Home Enhanced NodeB (HeNB) yang dapat meningkatkan area cakupan indoor. Di lain sisi HeNB menimbulkan interferensi baik uplink maupun downlink. Interferensi uplink terjadi antara user HeNB (HUE) dan user eNB (MUE) maupun sesama HUE. Interferensi ini mendegradasi kinerja sistem terutama dari sisi Signal to Interference plus Noise Ratio (SINR). Penelitian ini memberi penjelasan mengenai penerapan power control se...

  1. Recent Advances in Biological Control of Pest Insects by Using Viruses in China

    Institute of Scientific and Technical Information of China (English)

    Xiu-lian SUN; Hui-yin PENG

    2007-01-01

    Insect viruses are attractive as biological control agents and could be a feasible alternative to chemical insecticides in the management of insect infestations. This review describes recent advances in the development of wild-type and genetically modified viruses as insecticides. A new strategy of application of insect viruses in China is reviewed. Also, the assessment of biosafety of genetically modified Helicoverpa armigera Nucleopolyhedovirus (HearNPV) is emphasized as a case-study.

  2. Development of advanced NO sub x control concepts for coal-fired utility boilers

    Energy Technology Data Exchange (ETDEWEB)

    Newhall, J.; England, G.; Seeker, W.R.

    1991-12-23

    Energy and Environmental Research Corporation (EER) is currently conducting a test program to develop an advanced NO{sub x} control method utilizing reburning, promoted selective noncatalytic agent injection. The study will consist of fundamental and process testing over a large enough range of operating parameters to significantly reduce the risk of a full scale demonstration project. The test plan for the fundamental testing phase of the program is presented here.

  3. Development of Fuzzy Logic and Neural Network Control and Advanced Emissions Modeling for Parallel Hybrid Vehicles

    Energy Technology Data Exchange (ETDEWEB)

    Rajagopalan, A.; Washington, G.; Rizzoni, G.; Guezennec, Y.

    2003-12-01

    This report describes the development of new control strategies and models for Hybrid Electric Vehicles (HEV) by the Ohio State University. The report indicates results from models created in NREL's ADvanced VehIcle SimulatOR (ADVISOR 3.2), and results of a scalable IC Engine model, called in Willan's Line technique, implemented in ADVISOR 3.2.

  4. Advanced combustion, emission control, health impacts, and fuels merit review and peer evaluation

    Energy Technology Data Exchange (ETDEWEB)

    None, None

    2006-10-01

    This report is a summary and analysis of comments from the Advisory Panel at the FY 2006 DOE National Laboratory Advanced Combustion, Emission Control, Health Impacts, and Fuels Merit Review and Peer Evaluation, held May 15-18, 2006 at Argonne National Laboratory. The work evaluated in this document supports the FreedomCAR and Vehicle Technologies Program. The results of this merit review and peer evaluation are major inputs used by DOE in making its funding decisions for the upcoming fiscal year.

  5. Stringent comparative sequence analysis reveals SOX10 as a putative inhibitor of glial cell differentiation.

    Science.gov (United States)

    Gopinath, Chetna; Law, William D; Rodríguez-Molina, José F; Prasad, Arjun B; Song, Lingyun; Crawford, Gregory E; Mullikin, James C; Svaren, John; Antonellis, Anthony

    2016-11-07

    The transcription factor SOX10 is essential for all stages of Schwann cell development including myelination. SOX10 cooperates with other transcription factors to activate the expression of key myelin genes in Schwann cells and is therefore a context-dependent, pro-myelination transcription factor. As such, the identification of genes regulated by SOX10 will provide insight into Schwann cell biology and related diseases. While genome-wide studies have successfully revealed SOX10 target genes, these efforts mainly focused on myelinating stages of Schwann cell development. We propose that less-biased approaches will reveal novel functions of SOX10 outside of myelination. We developed a stringent, computational-based screen for genome-wide identification of SOX10 response elements. Experimental validation of a pilot set of predicted binding sites in multiple systems revealed that SOX10 directly regulates a previously unreported alternative promoter at SOX6, which encodes a transcription factor that inhibits glial cell differentiation. We further explored the utility of our computational approach by combining it with DNase-seq analysis in cultured Schwann cells and previously published SOX10 ChIP-seq data from rat sciatic nerve. Remarkably, this analysis enriched for genomic segments that map to loci involved in the negative regulation of gliogenesis including SOX5, SOX6, NOTCH1, HMGA2, HES1, MYCN, ID4, and ID2. Functional studies in Schwann cells revealed that: (1) all eight loci are expressed prior to myelination and down-regulated subsequent to myelination; (2) seven of the eight loci harbor validated SOX10 binding sites; and (3) seven of the eight loci are down-regulated upon repressing SOX10 function. Our computational strategy revealed a putative novel function for SOX10 in Schwann cells, which suggests a model where SOX10 activates the expression of genes that inhibit myelination during non-myelinating stages of Schwann cell development. Importantly, the

  6. Implementation and benefits of advanced process control for lithography CD and overlay

    Science.gov (United States)

    Zavyalova, Lena; Fu, Chong-Cheng; Seligman, Gary S.; Tapp, Perry A.; Pol, Victor

    2003-05-01

    Due to the rapidly reduced imaging process windows and increasingly stingent device overlay requirements, sub-130 nm lithography processes are more severely impacted than ever by systamic fault. Limits on critical dimensions (CD) and overlay capability further challenge the operational effectiveness of a mix-and-match environment using multiple lithography tools, as such mode additionally consumes the available error budgets. Therefore, a focus on advanced process control (APC) methodologies is key to gaining control in the lithographic modules for critical device levels, which in turn translates to accelerated yield learning, achieving time-to-market lead, and ultimately a higher return on investment. This paper describes the implementation and unique challenges of a closed-loop CD and overlay control solution in high voume manufacturing of leading edge devices. A particular emphasis has been placed on developing a flexible APC application capable of managing a wide range of control aspects such as process and tool drifts, single and multiple lot excursions, referential overlay control, 'special lot' handling, advanced model hierarchy, and automatic model seeding. Specific integration cases, including the multiple-reticle complementary phase shift lithography process, are discussed. A continuous improvement in the overlay and CD Cpk performance as well as the rework rate has been observed through the implementation of this system, and the results are studied.

  7. A Novel Percutaneous Electrode Implant for Improving Robustness in Advanced Myoelectric Control.

    Science.gov (United States)

    Hahne, Janne M; Farina, Dario; Jiang, Ning; Liebetanz, David

    2016-01-01

    Despite several decades of research, electrically powered hand and arm prostheses are still controlled with very simple algorithms that process the surface electromyogram (EMG) of remnant muscles to achieve control of one prosthetic function at a time. More advanced machine learning methods have shown promising results under laboratory conditions. However, limited robustness has largely prevented the transfer of these laboratory advances to clinical applications. In this paper, we introduce a novel percutaneous EMG electrode to be implanted chronically with the aim of improving the reliability of EMG detection in myoelectric control. The proposed electrode requires a minimally invasive procedure for its implantation, similar to a cosmetic micro-dermal implant. Moreover, being percutaneous, it does not require power and data telemetry modules. Four of these electrodes were chronically implanted in the forearm of an able-bodied human volunteer for testing their characteristics. The implants showed significantly lower impedance and greater robustness against mechanical interference than traditional surface EMG electrodes used for myoelectric control. Moreover, the EMG signals detected by the proposed systems allowed more stable control performance across sessions in different days than that achieved with classic EMG electrodes. In conclusion, the proposed implants may be a promising interface for clinically available prostheses.

  8. A Novel Percutaneous Electrode Implant for Improving Robustness in Advanced Myoelectric Control

    Directory of Open Access Journals (Sweden)

    Janne M. Hahne

    2016-03-01

    Full Text Available Despite several decades of research, electrically powered hand and arm prostheses are still controlled with very simple algorithms that process the surface electromyogram (EMG of remnant muscles to achieve control of one prosthetic function at a time. More advanced machine learning methods have shown promising results under laboratory conditions. However, limited robustness has largely prevented the transfer of these laboratory advances to clinical applications. In this paper, we introduce a novel percutaneous EMG electrode to be implanted chronically with the aim of improving the reliability of EMG detection in myoelectric control. The proposed electrode requires a minimally invasive procedure for its implantation, similar to a cosmetic micro-dermal implant. Moreover, being percutaneous, it does not require power and data telemetry modules. Four of these electrodes were chronically implanted in the forearm of an able-bodied human volunteer for testing their characteristics. The implants showed significantly lower impedance and greater robustness against mechanical interference than traditional surface EMG electrodes used for myoelectric control. Moreover, the EMG signals detected by the proposed systems allowed more stable control performance across sessions in different days than that achieved with classic EMG electrodes. In conclusion, the proposed implants may be a promising interface for clinically available prostheses.

  9. Advanced overlay: sampling and modeling for optimized run-to-run control

    Science.gov (United States)

    Subramany, Lokesh; Chung, WoongJae; Samudrala, Pavan; Gao, Haiyong; Aung, Nyan; Gomez, Juan Manuel; Gutjahr, Karsten; Park, DongSuk; Snow, Patrick; Garcia-Medina, Miguel; Yap, Lipkong; Demirer, Onur Nihat; Pierson, Bill; Robinson, John C.

    2016-03-01

    In recent years overlay (OVL) control schemes have become more complicated in order to meet the ever shrinking margins of advanced technology nodes. As a result, this brings up new challenges to be addressed for effective run-to- run OVL control. This work addresses two of these challenges by new advanced analysis techniques: (1) sampling optimization for run-to-run control and (2) bias-variance tradeoff in modeling. The first challenge in a high order OVL control strategy is to optimize the number of measurements and the locations on the wafer, so that the "sample plan" of measurements provides high quality information about the OVL signature on the wafer with acceptable metrology throughput. We solve this tradeoff between accuracy and throughput by using a smart sampling scheme which utilizes various design-based and data-based metrics to increase model accuracy and reduce model uncertainty while avoiding wafer to wafer and within wafer measurement noise caused by metrology, scanner or process. This sort of sampling scheme, combined with an advanced field by field extrapolated modeling algorithm helps to maximize model stability and minimize on product overlay (OPO). Second, the use of higher order overlay models means more degrees of freedom, which enables increased capability to correct for complicated overlay signatures, but also increases sensitivity to process or metrology induced noise. This is also known as the bias-variance trade-off. A high order model that minimizes the bias between the modeled and raw overlay signature on a single wafer will also have a higher variation from wafer to wafer or lot to lot, that is unless an advanced modeling approach is used. In this paper, we characterize the bias-variance trade off to find the optimal scheme. The sampling and modeling solutions proposed in this study are validated by advanced process control (APC) simulations to estimate run-to-run performance, lot-to-lot and wafer-to- wafer model term monitoring to

  10. Advances in quality control for dioxins monitoring and evaluation of measurement uncertainty from quality control data.

    Science.gov (United States)

    Eppe, Gauthier; De Pauw, Edwin

    2009-08-01

    This paper describes an application of multivariate and multilevel quality control charts with the aim of improving the internal quality control (IQC) procedures for the monitoring of dioxins and dioxin-like PCBs analysis in food. Dioxin analysts have to use the toxic equivalent concept (TEQ) to assess the toxicity potential of a mixture of dioxin-like compounds. The TEQ approach requires quantifying individually 29 dioxin-like compounds. Monitoring the congeners separately on univariate QC charts is misleading owing to the increase of false alarm rate. We propose to subdivide the TEQ value into 3 sub-groups and to control simultaneously the 3 variables in a T(2) chart. When a T(2) exceeds the upper control limit, it acts as a warning to trigger additional investigations on individual congeners. We discuss the minimum number of runs required to reliably estimate the QC chart parameters and we suggest using data from multilevel QC charts to properly characterize the standard deviations and the correlation coefficients. Moreover, the univariate QC chart can be sensitised to detect systematic errors by using exponentially weighted moving average (EWMA) technique. The EWMA chart provides an additional guidance on setting appropriate criteria to control the method bias and to support trend analysis. Finally, we present an estimate of measurement uncertainty by computing the accuracy profile in a retrospective way with the QC data generated and we discuss assessment of compliance with regulatory maximum levels.

  11. Improvement of environmental aspects of thermal power plant operation by advanced control concepts

    Directory of Open Access Journals (Sweden)

    Mikulandrić Robert

    2012-01-01

    Full Text Available The necessity of the reduction of greenhouse gas emissions, as formulated in the Kyoto Protocol, imposes the need for improving environmental aspects of existing thermal power plants operation. Improvements can be reached either by efficiency increment or by implementation of emission reduction measures. Investments in refurbishment of existing plant components or in plant upgrading by flue gas desulphurization, by primary and secondary measures of nitrogen oxides reduction, or by biomass co-firing, are usually accompanied by modernisation of thermal power plant instrumentation and control system including sensors, equipment diagnostics and advanced controls. Impact of advanced control solutions implementation depends on technical characteristics and status of existing instrumentation and control systems as well as on design characteristics and actual conditions of installed plant components. Evaluation of adequacy of implementation of advanced control concepts is especially important in Western Balkan region where thermal power plants portfolio is rather diversified in terms of size, type and commissioning year and where generally poor maintenance and lack of investments in power generation sector resulted in high greenhouse gases emissions and low efficiency of plants in operation. This paper is intended to present possibilities of implementation of advanced control concepts, and particularly those based on artificial intelligence, in selected thermal power plants in order to increase plant efficiency and to lower pollutants emissions and to comply with environmental quality standards prescribed in large combustion plant directive. [Acknowledgements. This paper has been created within WBalkICT - Supporting Common RTD actions in WBCs for developing Low Cost and Low Risk ICT based solutions for TPPs Energy Efficiency increasing, SEE-ERA.NET plus project in cooperation among partners from IPA SA - Romania, University of Zagreb - Croatia and Vinca

  12. DEMONSTRATION OF AN ADVANCED INTEGRATED CONTROL SYSTEM FOR SIMULTANEOUS EMISSIONS REDUCTION

    Energy Technology Data Exchange (ETDEWEB)

    Suzanne Shea; Randhir Sehgal; Ilga Celmins; Andrew Maxson

    2002-02-01

    The primary objective of the project titled ''Demonstration of an Advanced Integrated Control System for Simultaneous Emissions Reduction'' was to demonstrate at proof-of-concept scale the use of an online software package, the ''Plant Environmental and Cost Optimization System'' (PECOS), to optimize the operation of coal-fired power plants by economically controlling all emissions simultaneously. It combines physical models, neural networks, and fuzzy logic control to provide both optimal least-cost boiler setpoints to the boiler operators in the control room, as well as optimal coal blending recommendations designed to reduce fuel costs and fuel-related derates. The goal of the project was to demonstrate that use of PECOS would enable coal-fired power plants to make more economic use of U.S. coals while reducing emissions.

  13. Introduction to the special issue on Advances in intelligent nonlinear control for robotic systems

    Institute of Scientific and Technical Information of China (English)

    Chee Khiang PANG; Huajin TANG; Qing Wei JIA

    2010-01-01

    @@ In the last two decades, robotic systems have achieved wide applications in every aspect of human society, including industrial manufacturing, automotive production, medical devices, and social lives. With the diversity of application do-mains, control techniques have pervaded from industrial robot manipulators, wheeled or legged mobile robots, unmanned autonomous aerial, ground, and underwater vehicles, to humanoid robots, and haptic devices, etc. The growing number of applications of robotics and increasing requirements for system stability, reliability, and safety, are posing new and challenging theoretical and technological problems for modeling and control of these highly nonlinear systems. Control of these complex systems is highly challenging due to the inherent nonlinear response and strong heterogeneity in dif-ferent parts as computers, sensors, hardware objects, etc. As such, novel nonlinear control strategies are essential to the advancement of robotic systems and corresponding technologies.

  14. Analysis and synthesis of networked control systems: A survey of recent advances and challenges.

    Science.gov (United States)

    Zhang, Dan; Shi, Peng; Wang, Qing-Guo; Yu, Li

    2017-01-01

    A networked control system (NCS) is a control system which involves a communication network. In NCSs, the continuous-time measurement is usually sampled and quantized before transmission. Then, the measurement is transmitted to the remote controller via the communication channel, during which the signal may be delayed, lost or even sometimes not allowed for transmission due to the communication or energy constraints. In recent years, the modeling, analysis and synthesis of networked control systems (NCSs) have received great attention, which leads to a large number of publications. This paper attempts to present an overview of recent advances and unify them in a framework of network-induced issues such as signal sampling, data quantization, communication delay, packet dropouts, medium access constraints, channel fading and power constraint, and present respective solution approaches to each of these issues. We draw some conclusions and highlight future research directions in end.

  15. Advanced nitrogen removal by pulsed sequencing batch reactors (SBR) with real-time control

    Institute of Scientific and Technical Information of China (English)

    YANG Qing; PENG Yongzhen; YANG Anming; GUO Jianhua; LI Jianfeng

    2007-01-01

    The feasibility of pH and oxidation reduction potential (ORP) as on-line control parameters to advance nitrogen removal in pulsed sequencing batch reactors (SBR)was evaluated.The pulsed SBR,a novel operational mode of SBR,was utilized to treat real municipal wastewater accompanied with adding ethanol as external carbon source.It was observed that the bending-point (apex and knee) of pH and ORP profiles can be used to control denitrification process at a low influent C/N ratio while dpH/dt can be used to control the nitrification and denitrification process at a high influent C/N ratio.The experimental results demonstrated that the effluent total nitrogen can be reduced to lower than 2 mg/L,and the average total nitrogen (TN) removal efficiency was higher than 98% by using real-time controll strategy.

  16. Advanced control techniques for post-buckled precompressed (PBP) flight control actuators

    NARCIS (Netherlands)

    Groen, M.; Van Schravendijk, M.; Barrett, R.; Vos, R.

    2009-01-01

    The dynamic response of a new class of flight control actuators that rely on post-buckled recompressed (PBP) piezoelectric elements is investigated. While past research has proven that PBP actuators are capable of generating deflections three times higher than conventional bimorph actuators, this pa

  17. Getting ready to use control: Advances in the measurement of young children's use of proactive control.

    Science.gov (United States)

    Doebel, Sabine; Barker, Jane E; Chevalier, Nicolas; Michaelson, Laura E; Fisher, Anna V; Munakata, Yuko

    2017-01-01

    A key developmental transition in executive function is in the temporal dynamics of its engagement: children shift from reactively calling to mind task-relevant information as needed, to being able to proactively maintain information across time in anticipation of upcoming demands. This transition is important for understanding individual differences and developmental changes in executive function; however, methods targeting its assessment are limited. We tested the possibility that Track-It, a paradigm developed to measure selective sustained attention, also indexes proactive control. In this task children must track a target shape as it moves unpredictably among moving distractors, and identify where it disappears, which may require proactively maintaining information about the target or goal. In two experiments (5-6 year-olds, Ns = 33, 64), children's performance on Track-It predicted proactive control across two established paradigms. These findings suggest Track-It measures proactive control in children. Theoretical possibilities regarding how proactive control and selective sustained attention may be related are also discussed.

  18. Advanced concept for damage control : A framework to simulate fire propagation and damage control effects

    NARCIS (Netherlands)

    Gillis, M.P.W.; Keijer, W.; Smit, C.S.

    2003-01-01

    Current damage control procedures are developed on the basis of a long-standing experience. However there are reasons to believe that these procedures do not account for major weapon-induced calamities. Fire fighting after substantial blast and fragmentation damage, due to a weaponhit, is quite beyo

  19. Advanced concept for damage control : A framework to simulate fire propagation and damage control effects

    NARCIS (Netherlands)

    Gillis, M.P.W.; Keijer, W.; Smit, C.S.

    2003-01-01

    Current damage control procedures are developed on the basis of a long-standing experience. However there are reasons to believe that these procedures do not account for major weapon-induced calamities. Fire fighting after substantial blast and fragmentation damage, due to a weaponhit, is quite

  20. Simplified and advanced modelling of traction control systems of heavy-haul locomotives

    Science.gov (United States)

    Spiryagin, Maksym; Wolfs, Peter; Szanto, Frank; Cole, Colin

    2015-05-01

    Improving tractive effort is a very complex task in locomotive design. It requires the development of not only mechanical systems but also power systems, traction machines and traction algorithms. At the initial design stage, traction algorithms can be verified by means of a simulation approach. A simple single wheelset simulation approach is not sufficient because all locomotive dynamics are not fully taken into consideration. Given that many traction control strategies exist, the best solution is to use more advanced approaches for such studies. This paper describes the modelling of a locomotive with a bogie traction control strategy based on a co-simulation approach in order to deliver more accurate results. The simplified and advanced modelling approaches of a locomotive electric power system are compared in this paper in order to answer a fundamental question. What level of modelling complexity is necessary for the investigation of the dynamic behaviours of a heavy-haul locomotive running under traction? The simulation results obtained provide some recommendations on simulation processes and the further implementation of advanced and simplified modelling approaches.

  1. Technology Roadmap Instrumentation, Control, and Human-Machine Interface to Support DOE Advanced Nuclear Energy Programs

    Energy Technology Data Exchange (ETDEWEB)

    Donald D Dudenhoeffer; Burce P Hallbert

    2007-03-01

    Instrumentation, Controls, and Human-Machine Interface (ICHMI) technologies are essential to ensuring delivery and effective operation of optimized advanced Generation IV (Gen IV) nuclear energy systems. In 1996, the Watts Bar I nuclear power plant in Tennessee was the last U.S. nuclear power plant to go on line. It was, in fact, built based on pre-1990 technology. Since this last U.S. nuclear power plant was designed, there have been major advances in the field of ICHMI systems. Computer technology employed in other industries has advanced dramatically, and computing systems are now replaced every few years as they become functionally obsolete. Functional obsolescence occurs when newer, more functional technology replaces or supersedes an existing technology, even though an existing technology may well be in working order.Although ICHMI architectures are comprised of much of the same technology, they have not been updated nearly as often in the nuclear power industry. For example, some newer Personal Digital Assistants (PDAs) or handheld computers may, in fact, have more functionality than the 1996 computer control system at the Watts Bar I plant. This illustrates the need to transition and upgrade current nuclear power plant ICHMI technologies.

  2. Advanced nonlinear control: Robustness and stability with applications to aircraft flight control systems

    Science.gov (United States)

    Frye, Michael Takaichi

    This dissertation examines the problem of global decentralized control by output feedback for large-scale uncertain nonlinear systems whose subsystems are interconnected not only by their outputs but also by their unmeasurable states. Several innovative techniques will be developed to create decentralized output feedback controllers rendering the closed-loop systems globally asymptotically stable. This is accomplished by extending an output feedback domination design that requires only limited information about the nonlinear system. We will apply our design to lower, upper, and non-triangular nonlinear systems. A time-varying output feedback controller is also constructed for use with large-scale systems that have unknown parameters. Furthermore, a mixed large-scale system consisting of both lower and upper triangular systems is shown to be stabilizable by employing a combined high and low gain domination technique. The significance of our results is that we do not need to have prior information about the nonlinearities of the system. In addition, a new design technique was developed using homogeneous system theory, which allows for the design of nonsmooth controllers and observers to stabilize a class of feedforward system with uncontrollable and unobservable linearization. An example of a large-scale system is a group of autonomous airships performing the function of a temporary mobile cell phone network. An airship mobile cell phone network is a novel solution to the problem of maintaining communication during the advent of extensive damage to the communication infrastructure; be it from a flood, earthquake, hurricane, or terrorist attack. A first principle force-based dynamic model for the Tri-Turbofan Airship was developed and will be discussed in detail. The mathematical model was based on actual flight test data that has been collected at the Gait Analysis and Innovative Technologies Laboratory. This model was developed to research autonomous airship

  3. Recent advances of rearing cabinet instrumentation and control system for insect stock culture

    Science.gov (United States)

    Hermawan, Wawan; Kasmara, Hikmat; Melanie, Panatarani, Camellia; Joni, I. Made

    2017-01-01

    Helicoverpa armigera (Hubner) is one of a serious pest of horticulture in Indonesia. Helicoverpa armigera Nuclear Polyhedrovirus (HaNPV) has attracted interest for many researchers as a pest control for larvae of this species. Currently, we investigating the agrochemical formulations of HaNPV by introducing nanotechnology. Thus it is required an acceptable efficiency of insect stock cultures equipped with advance instruments to resolve the difficulties on insect stock seasons dependency. In addition, it is important to improve the insect survival with the aid of artificial natural environment and gain high insect production. This paper reports the rearing cabinet used as preparation of stock culture includes air-conditioning system, lighting, i.e. day and night control, and the main principles on recent technical and procedural advances apparatus of the system. The rearing system was moveable, designed and build by allowing air-conditioned cabinet for rearing insects, air motion and distribution as well as temperature and humidity being precisely controlled. The air was heated, humidified, and dehumidified respectively using a heater and ultrasonic nebulizer as actuators. Temperature and humidity can be controlled at any desired levels from room temperature (20°C) to 40 ± 1°C and from 0 to 80% RH with an accuracy of ±3% R.H. It is concluded that the recent design has acceptable performance based on the defined requirement for insect rearing and storage.

  4. Software control of the Advanced Technology Solar Telescope enclosure PLC hardware using COTS software

    Science.gov (United States)

    Borrowman, Alastair J.; de Bilbao, Lander; Ariño, Javier; Murga, Gaizka; Goodrich, Bret; Hubbard, John R.; Greer, Alan; Mayer, Chris; Taylor, Philip

    2012-09-01

    As PLCs evolve from simple logic controllers into more capable Programmable Automation Controllers (PACs), observatories are increasingly using such devices to control complex mechanisms1, 2. This paper describes use of COTS software to control such hardware using the Advanced Technology Solar Telescope (ATST) Common Services Framework (CSF). We present the Enclosure Control System (ECS) under development in Spain and the UK. The paper details selection of the commercial PLC communication library PLCIO. Implemented in C and delivered with source code, the library separates the programmer from communication details through a simple API. Capable of communicating with many types of PLCs (including Allen-Bradley and Siemens) the API remains the same irrespective of PLC in use. The ECS is implemented in Java using the observatory's framework that provides common services for software components. We present a design following a connection-based approach where all components access the PLC through a single connection class. The link between Java and PLCIO C library is provided by a thin Java Native Interface (JNI) layer. Also presented is a software simulator of the PLC based upon the PLCIO Virtual PLC. This creates a simulator operating below the library's API and thus requires no change to ECS software. It also provides enhanced software testing capabilities prior to hardware becoming available. Results are presented in the form of communication timing test data, showing that the use of CSF, JNI and PLCIO provide a control system capable of controlling enclosure tracking mechanisms, that would be equally valid for telescope mount control.

  5. Interim results of the study of control room crew staffing for advanced passive reactor plants

    Energy Technology Data Exchange (ETDEWEB)

    Hallbert, B.P.; Sebok, A.; Haugset, K. [OECD Halden Reactor Project (Norway)

    1996-03-01

    Differences in the ways in which vendors expect the operations staff to interact with advanced passive plants by vendors have led to a need for reconsideration of the minimum shift staffing requirements of licensed Reactor Operators and Senior Reactor Operators contained in current federal regulations (i.e., 10 CFR 50.54(m)). A research project is being carried out to evaluate the impact(s) of advanced passive plant design and staffing of control room crews on operator and team performance. The purpose of the project is to contribute to the understanding of potential safety issues and provide data to support the development of design review guidance. Two factors are being evaluated across a range of plant operating conditions: control room crew staffing; and characteristics of the operating facility itself, whether it employs conventional or advanced, passive features. This paper presents the results of the first phase of the study conducted at the Loviisa nuclear power station earlier this year. Loviisa served as the conventional plant in this study. Data collection from four crews were collected from a series of design basis scenarios, each crew serving in either a normal or minimum staffing configuration. Results of data analyses show that crews participating in the minimum shift staffing configuration experienced significantly higher workload, had lower situation awareness, demonstrated significantly less effective team performance, and performed more poorly as a crew than the crews participating in the normal shift staffing configuration. The baseline data on crew configurations from the conventional plant setting will be compared with similar data to be collected from the advanced plant setting, and a report prepared providing the results of the entire study.

  6. Induction of a stringent metabolic response in intracellular stages of Leishmania mexicana leads to increased dependence on mitochondrial metabolism.

    Directory of Open Access Journals (Sweden)

    Eleanor C Saunders

    2014-01-01

    Full Text Available Leishmania parasites alternate between extracellular promastigote stages in the insect vector and an obligate intracellular amastigote stage that proliferates within the phagolysosomal compartment of macrophages in the mammalian host. Most enzymes involved in Leishmania central carbon metabolism are constitutively expressed and stage-specific changes in energy metabolism remain poorly defined. Using (13C-stable isotope resolved metabolomics and (2H2O labelling, we show that amastigote differentiation is associated with reduction in growth rate and induction of a distinct stringent metabolic state. This state is characterized by a global decrease in the uptake and utilization of glucose and amino acids, a reduced secretion of organic acids and increased fatty acid β-oxidation. Isotopomer analysis showed that catabolism of hexose and fatty acids provide C4 dicarboxylic acids (succinate/malate and acetyl-CoA for the synthesis of glutamate via a compartmentalized mitochondrial tricarboxylic acid (TCA cycle. In vitro cultivated and intracellular amastigotes are acutely sensitive to inhibitors of mitochondrial aconitase and glutamine synthetase, indicating that these anabolic pathways are essential for intracellular growth and virulence. Lesion-derived amastigotes exhibit a similar metabolism to in vitro differentiated amastigotes, indicating that this stringent response is coupled to differentiation signals rather than exogenous nutrient levels. Induction of a stringent metabolic response may facilitate amastigote survival in a nutrient-poor intracellular niche and underlie the increased dependence of this stage on hexose and mitochondrial metabolism.

  7. Induction of a Stringent Metabolic Response in Intracellular Stages of Leishmania mexicana Leads to Increased Dependence on Mitochondrial Metabolism

    Science.gov (United States)

    Saunders, Eleanor C.; Ng, William W.; Kloehn, Joachim; Chambers, Jennifer M.; Ng, Milica; McConville, Malcolm J.

    2014-01-01

    Leishmania parasites alternate between extracellular promastigote stages in the insect vector and an obligate intracellular amastigote stage that proliferates within the phagolysosomal compartment of macrophages in the mammalian host. Most enzymes involved in Leishmania central carbon metabolism are constitutively expressed and stage-specific changes in energy metabolism remain poorly defined. Using 13C-stable isotope resolved metabolomics and 2H2O labelling, we show that amastigote differentiation is associated with reduction in growth rate and induction of a distinct stringent metabolic state. This state is characterized by a global decrease in the uptake and utilization of glucose and amino acids, a reduced secretion of organic acids and increased fatty acid β-oxidation. Isotopomer analysis showed that catabolism of hexose and fatty acids provide C4 dicarboxylic acids (succinate/malate) and acetyl-CoA for the synthesis of glutamate via a compartmentalized mitochondrial tricarboxylic acid (TCA) cycle. In vitro cultivated and intracellular amastigotes are acutely sensitive to inhibitors of mitochondrial aconitase and glutamine synthetase, indicating that these anabolic pathways are essential for intracellular growth and virulence. Lesion-derived amastigotes exhibit a similar metabolism to in vitro differentiated amastigotes, indicating that this stringent response is coupled to differentiation signals rather than exogenous nutrient levels. Induction of a stringent metabolic response may facilitate amastigote survival in a nutrient-poor intracellular niche and underlie the increased dependence of this stage on hexose and mitochondrial metabolism. PMID:24465208

  8. Advances in quantum control of three-level superconducting circuit architectures

    Energy Technology Data Exchange (ETDEWEB)

    Falci, G.; Paladino, E. [Dipartimento di Fisica e Astronomia, Universita di Catania (Italy); CNR-IMM UOS Universita (MATIS), Consiglio Nazionale delle Ricerche, Catania (Italy); INFN, Sezione di Catania (Italy); Di Stefano, P.G. [Dipartimento di Fisica e Astronomia, Universita di Catania (Italy); Centre for Theoretical Atomic, Molecular and Optical Physics, School of Mathematics and Physics, Queen' s University Belfast(United Kingdom); Ridolfo, A.; D' Arrigo, A. [Dipartimento di Fisica e Astronomia, Universita di Catania (Italy); Paraoanu, G.S. [Low Temperature Laboratory, Department of Applied Physics, Aalto University School of Science (Finland)

    2017-06-15

    Advanced control in Lambda (Λ) scheme of a solid state architecture of artificial atoms and quantized modes would allow the translation to the solid-state realm of a whole class of phenomena from quantum optics, thus exploiting new physics emerging in larger integrated quantum networks and for stronger couplings. However control solid-state devices has constraints coming from selection rules, due to symmetries which on the other hand yield protection from decoherence, and from design issues, for instance that coupling to microwave cavities is not directly switchable. We present two new schemes for the Λ-STIRAP control problem with the constraint of one or two classical driving fields being always-on. We show how these protocols are converted to apply to circuit-QED architectures. We finally illustrate an application to coherent spectroscopy of the so called ultrastrong atom-cavity coupling regime. (copyright 2016 WILEY-VCH Verlag GmbH and Co. KGaA, Weinheim)

  9. The Application of Advancements in Computer Technology to the Control and Safety System of CANDU Reactors

    Energy Technology Data Exchange (ETDEWEB)

    Chan, P. S. W. [AECL CANDU/Sheridan Park Research Community, Ontario (Canada)

    1992-04-15

    The present spatial control algorithm in CANDU reactors is based on flux synthesis from a set of parti-coloured harmonic flux modes. The design of the Rop system is also based on parti-coloured flux shapes, including both normal and abnormal reactor operating conditions. The dependency of the control and safety systems on parti-coloured data was necessitated by the slow CPU and by the scarcity of Ram which were available to the computer systems in the early seventies. Recent advancements in high speed microprocessors and high capacity Ram chips enable the development of the Pmfp computer code, which calculates reactor power distribution on-line, using diffusion theory and in-core self-powered flux detector readings as internal boundary conditions. The Pmfp based control and safety systems do not depend on parti-coloured flux shapes or preconceived reactor operating conditions.

  10. Advanced Transport Operating System (ATOPS) Flight Management/Flight Controls (FM/FC) software description

    Science.gov (United States)

    Wolverton, David A.; Dickson, Richard W.; Clinedinst, Winston C.; Slominski, Christopher J.

    1993-01-01

    The flight software developed for the Flight Management/Flight Controls (FM/FC) MicroVAX computer used on the Transport Systems Research Vehicle for Advanced Transport Operating Systems (ATOPS) research is described. The FM/FC software computes navigation position estimates, guidance commands, and those commands issued to the control surfaces to direct the aircraft in flight. Various modes of flight are provided for, ranging from computer assisted manual modes to fully automatic modes including automatic landing. A high-level system overview as well as a description of each software module comprising the system is provided. Digital systems diagrams are included for each major flight control component and selected flight management functions.

  11. Advanced Emergency Braking Controller Design for Pedestrian Protection Oriented Automotive Collision Avoidance System

    Directory of Open Access Journals (Sweden)

    Guo Lie

    2014-01-01

    Full Text Available Automotive collision avoidance system, which aims to enhance the active safety of the vehicle, has become a hot research topic in recent years. However, most of the current systems ignore the active protection of pedestrian and other vulnerable groups in the transportation system. An advanced emergency braking control system is studied by taking into account the pedestrians and the vehicles. Three typical braking scenarios are defined and the safety situations are assessed by comparing the current distance between the host vehicle and the obstacle with the critical braking distance. To reflect the nonlinear time-varying characteristics and control effect of the longitudinal dynamics, the vehicle longitudinal dynamics model is established in CarSim. Then the braking controller with the structure of upper and lower layers is designed based on sliding mode control and the single neuron PID control when confronting deceleration or emergency braking conditions. Cosimulations utilizing CarSim and Simulink are finally carried out on a CarSim intelligent vehicle model to explore the effectiveness of the proposed controller. Results display that the designed controller has a good response in preventing colliding with the front vehicle or pedestrian.

  12. A variable structure unified power flow controller for advanced industrial application

    Energy Technology Data Exchange (ETDEWEB)

    Ma, T.-T.

    2004-07-01

    This paper presents a new application example of flexible ac transmission systems (FACTS) devices in the advanced industrial power control schemes. An integrated multi-functional power quality controller and energy saving system based on the unified power flow controller (UPFC) is proposed. The proposed integrated system can compensate the reactive power, harmonic current and the unbalanced power of the controlled distribution system with a capacity-limitation manner by its shunt branch. It also can regulate multiple load voltages simultaneously based on the prescribed P-V characteristics of distinct loads for the purpose of energy saving via its series branch. The detailed design procedure of the controllers providing flexible hardware configuration and multiple control functions is presented. A 15 KVA test-system with the variable structure UPFC configuration performing active power filter functions and simultaneously regulating an 7HP induction motor for energy saving is numerically investigated with EMTP programs. The feasibility and effectiveness of the proposed system and the related control techniques are confirmed through some simulation results. (author)

  13. Euler Technology Assessment - SPLITFLOW Code Applications for Stability and Control Analysis on an Advanced Fighter Model Employing Innovative Control Concepts

    Science.gov (United States)

    Jordan, Keith J.

    1998-01-01

    This report documents results from the NASA-Langley sponsored Euler Technology Assessment Study conducted by Lockheed-Martin Tactical Aircraft Systems (LMTAS). The purpose of the study was to evaluate the ability of the SPLITFLOW code using viscous and inviscid flow models to predict aerodynamic stability and control of an advanced fighter model. The inviscid flow model was found to perform well at incidence angles below approximately 15 deg, but not as well at higher angles of attack. The results using a turbulent, viscous flow model matched the trends of the wind tunnel data, but did not show significant improvement over the Euler solutions. Overall, the predictions were found to be useful for stability and control design purposes.

  14. Quality Control Methodologies for Advanced EMI Sensor Data Acquisition and Anomaly Classification - Former Southwestern Proving Ground, Arkansas

    Science.gov (United States)

    2015-07-01

    DEMONSTRATION REPORT Quality Control Methodologies for Advanced EMI Sensor Data Acquisition and Anomaly Classification – Former Southwestern...concentrations. A total of 11.23 acres of dynamic surveys were conducted using MetalMapper advanced electromagnetic induction ( EMI ) sensor. A total of...Order Navigation Points ................................................................................13 5.2.3 Initial EMI Survey

  15. Plasma Shape and Current Density Profile Control in Advanced Tokamak Operating Scenarios

    Science.gov (United States)

    Shi, Wenyu

    The need for new sources of energy is expected to become a critical problem within the next few decades. Nuclear fusion has sufficient energy density to potentially supply the world population with its increasing energy demands. The tokamak is a magnetic confinement device used to achieve controlled fusion reactions. Experimental fusion technology has now reached a level where tokamaks are able to produce about as much energy as is expended in heating the fusion fuel. The next step towards the realization of a nuclear fusion tokamak power plant is ITER, which will be capable of exploring advanced tokamak (AT) modes, characterized by a high fusion gain and plasma stability. The extreme requirements of the advanced modes motivates researchers to improve the modeling of the plasma response as well as the design of feedback controllers. This dissertation focuses on several magnetic and kinetic control problems, including the plasma current, position and shape control, and data-driven and first-principles-driven modeling and control of plasma current density profile and the normalized plasma pressure ratio betaN. The plasma is confined within the vacuum vessel by an external electromagnetic field, produced primarily by toroidal and poloidal field coils. The outermost closed plasma surface or plasma boundary is referred to as the shape of the plasma. A central characteristic of AT plasma regimes is an extreme elongated shape. The equilibrium among the electromagnetic forces acting on an elongated plasma is unstable. Moreover, the tokamak performance is improved if the plasma is located in close proximity to the torus wall, which guarantees an efficient use of available volume. As a consequence, feedback control of the plasma position and shape is necessary. In this dissertation, an Hinfinity-based, multi-input-multi-output (MIMO) controller for the National Spherical Torus Experiment (NSTX) is developed, which is used to control the plasma position, shape, and X

  16. Effect of pravastatin on survival in patients with advanced hepatocellular carcinoma. A randomized controlled trial.

    Science.gov (United States)

    Kawata, S; Yamasaki, E; Nagase, T; Inui, Y; Ito, N; Matsuda, Y; Inada, M; Tamura, S; Noda, S; Imai, Y; Matsuzawa, Y

    2001-04-06

    Chemotherapy is not effective for hepatocellular carcinoma (HCC). HMG-CoA redutase inhibitors have cytostatic activity for cancer cells, but their clinical usefulness is unknown. To investigate whether pravastatin, a potent HMG-CoA reductase inhibitor, prolongs survival in patients with advanced HCC, this randomized controlled trial was conducted between February 1990 and February 1998 at Osaka University Hospital. 91 consecutive patients <71 years old (mean age 62) with unresectable HCC were enroled in this study. 8 patients were withdrawn because of progressive liver dysfunction; 83 patients were randomized to standard treatment with or without pravastatin. All patients underwent transcatheter arterial embolization (TAE) followed by oral 5-FU 200 mg(-1)d for 2 months. Patients were then randomly assigned to control (n = 42) and pravastatin (n = 41) groups. Pravastatin was administered at a daily dose of 40 mg. The effect of pravastatin on tumour growth was assessed by ultrasonography. Primary endpoint was death due to progression of HCC. The duration of pravastatin administration was 16.5 +/- 9.8 months (mean +/- SD). No patients in either group were lost to follow-up. Median survival was 18 months in the pravastatin group versus 9 months in controls (P = 0.006). The Cox proportional hazards model showed that pravastatin was a significant factor contributing to survival. Pravastatin prolonged the survival of patients with advanced HCC, suggesting its value for adjuvant treatment.

  17. Expanding Robust HCCI Operation with Advanced Valve and Fuel Control Technologies

    Energy Technology Data Exchange (ETDEWEB)

    Szybist, J. P. [Oak Ridge National Lab., Oak Ridge, TN (United States); Confer, K. [Delphi Automotive Systems (United States)

    2012-09-11

    Delphi Automotive Systems and ORNL established this CRADA to advance the commercialization potential of the homogeneous charge compression ignition (HCCI) advanced combustion strategy for gasoline engine platforms. HCCI combustion has been shown by others to produce high diesel-like efficiency on a gasoline engine platform while simultaneously producing low NOX and particulate matter emissions. However, the commercialization barriers that face HCCI combustion are significant, with requirements for a more active engine control system, likely with next-cycle closed-loop feedback control, and with advanced valve train technologies to enable negative valve overlap conditions. In the partnership between Delphi and ORNL, each organization brought a unique and complementary set of skills to the project. Delphi has made a number of breakthroughs with production-intent valve train technologies and controls in recent years to make a part time production-intent HCCI engine plausible. ORNL has extensive knowledge and expertise with HCCI combustion, and also has a versatile research engine with hydraulic valve actuation (HVA) that is useful for guiding production of a cam-based HCCI system. Partnering these knowledge bases and capabilities was essential towards making progress to better understand HCCI combustion and the commercialization barriers that it faces. ORNL and Delphi maintained strong collaboration throughout the project. Meetings were held regularly, with additional reports, presentations, and meetings as necessary to maintain progress. Delphi provided guidance to ORNL regarding operational strategies to investigate on their single-cylinder research engine with HVA and data from their experimental multi-cylinder engine for modeling. ORNL provided single-cylinder engine data and modeling results.

  18. Advanced Guidance and Control Methods for Reusable Launch Vehicles: Test Results

    Science.gov (United States)

    Hanson, John M.; Jones, Robert E.; Krupp, Don R.; Fogle, Frank R. (Technical Monitor)

    2002-01-01

    There are a number of approaches to advanced guidance and control (AG&C) that have the potential for achieving the goals of significantly increasing reusable launch vehicle (RLV) safety/reliability and reducing the cost. In this paper, we examine some of these methods and compare the results. We briefly introduce the various methods under test, list the test cases used to demonstrate that the desired results are achieved, show an automated test scoring method that greatly reduces the evaluation effort required, and display results of the tests. Results are shown for the algorithms that have entered testing so far.

  19. Coal surface control for advanced fine coal flotation. Final report, October 1, 1988--March 31, 1992

    Energy Technology Data Exchange (ETDEWEB)

    Fuerstenau, D.W.; Hanson, J.S.; Diao, J.; Harris, G.H.; De, A.; Sotillo, F. [California Univ., Berkeley, CA (United States); Somasundaran, P.; Harris, C.C.; Vasudevan, T.; Liu, D.; Li, C. [Columbia Univ., New York, NY (United States); Hu, W.; Zou, Y.; Chen, W. [Utah Univ., Salt Lake City, UT (United States); Choudhry, V.; Shea, S.; Ghosh, A.; Sehgal, R. [Praxis Engineers, Inc., Milpitas, CA (United States)

    1992-03-01

    The initial goal of the research project was to develop methods of coal surface control in advanced froth flotation to achieve 90% pyritic sulfur rejection, while operating at Btu recoveries above 90% based on run-of-mine quality coal. Moreover, the technology is to concomitantly reduce the ash content significantly (to six percent or less) to provide a high-quality fuel to the boiler (ash removal also increases Btu content, which in turn decreases a coal`s emission potential in terms of lbs SO{sub 2}/million Btu). (VC)

  20. System and method to control h2o2 level in advanced oxidation processes

    DEFF Research Database (Denmark)

    2016-01-01

    The present invention relates to a bio-electrochemical system (BES) and a method of in-situ production and removal of H2O2 using such a bio-electrochemical system (BES). Further, the invention relates to a method for in-situ control of H2O2 content in an aqueous system of advanced oxidation...... processes (AOPs) involving in-situ generation of hydroxyl radical (OH) by using such a bio-electrochemical system (BES) and to a method for treatment of wastewater and water disinfection. The bio-electrochemical system (BES) according to the invention comprises: - an aqueous cathode compartment comprising...

  1. RECENT ADVANCES IN THE PREPARATION OF MOLECULARLY IMPRINTED POLYMERS VIA CONTROLLED RADICAL POLYMERIZATION TECHNIQUES

    Institute of Scientific and Technical Information of China (English)

    2008-01-01

    Molecular imprinting technique is a simple and efficient method for the preparation of polymer materials (i.e., molecularly imprinted polymers, MIPs) with tailor-made recognition sites for certain target molecules. The resulting MIPs have proven to be versatile synthetic receptors due to their high specific recognition ability, favorable mechanical, thermal and chemical stability, and ease of preparation. Recent years have witnessed significant progress in the synthesis and applications of MIPs. This review focus on the recent developments and advances in the preparation of MIPs via various controlled radical polymerization techniques.

  2. RECENT ADVANCES IN THE PREPARATION OF MOLECULARLY IMPRINTED POLYMERS VIA CONTROLLED RADICAL POLYMERIZATION TECHNIQUES

    Institute of Scientific and Technical Information of China (English)

    ZHANG Ying; ZHANG Huiqi

    2008-01-01

    Molecular imprinting technique is a simple and efficient method for the preparation of polymer materials (i.e., molecularly imprinted polymers, MIPs) with tailor-made recognition sites for certain target molecules.The resulting MIPs have proven to be versatile synthetic receptors due to their high specific recognition ability, favorable mechanical, thermal and chemical stability, and ease of preparation.Recent years have witnessed signifwant progress in the synthesis and applications of MIPs.This review focus on the recent developments and advances in the preparation of MIPs via various controlled radical polymerization techniques.

  3. Recombinant factor VIIa for variceal bleeding in patients with advanced cirrhosis: A randomized, controlled trial

    DEFF Research Database (Denmark)

    Bosch, Jaime; Thabut, Dominique; Albillos, Agustín;

    2008-01-01

    A beneficial effect of recombinant activated factor VII (rFVIIa) in Child-Pugh class B and C patients with cirrhosis who have variceal bleeding has been suggested. This randomized controlled trial assessed the efficacy and safety of rFVIIa in patients with advanced cirrhosis and active variceal...... events, were comparable between groups. CONCLUSION: Treatment with rFVIIa had no significant effect on the primary composite endpoint compared with placebo. Therefore, decision on the use of this hemostatic agent in acute variceal bleeding should be carefully considered, because results of this study do...

  4. Stringent homology-based prediction of H. sapiens-M. tuberculosis H37Rv protein-protein interactions.

    Science.gov (United States)

    Zhou, Hufeng; Gao, Shangzhi; Nguyen, Nam Ninh; Fan, Mengyuan; Jin, Jingjing; Liu, Bing; Zhao, Liang; Xiong, Geng; Tan, Min; Li, Shijun; Wong, Limsoon

    2014-04-08

    H. sapiens-M. tuberculosis H37Rv protein-protein interaction (PPI) data are essential for understanding the infection mechanism of the formidable pathogen M. tuberculosis H37Rv. Computational prediction is an important strategy to fill the gap in experimental H. sapiens-M. tuberculosis H37Rv PPI data. Homology-based prediction is frequently used in predicting both intra-species and inter-species PPIs. However, some limitations are not properly resolved in several published works that predict eukaryote-prokaryote inter-species PPIs using intra-species template PPIs. We develop a stringent homology-based prediction approach by taking into account (i) differences between eukaryotic and prokaryotic proteins and (ii) differences between inter-species and intra-species PPI interfaces. We compare our stringent homology-based approach to a conventional homology-based approach for predicting host-pathogen PPIs, based on cellular compartment distribution analysis, disease gene list enrichment analysis, pathway enrichment analysis and functional category enrichment analysis. These analyses support the validity of our prediction result, and clearly show that our approach has better performance in predicting H. sapiens-M. tuberculosis H37Rv PPIs. Using our stringent homology-based approach, we have predicted a set of highly plausible H. sapiens-M. tuberculosis H37Rv PPIs which might be useful for many of related studies. Based on our analysis of the H. sapiens-M. tuberculosis H37Rv PPI network predicted by our stringent homology-based approach, we have discovered several interesting properties which are reported here for the first time. We find that both host proteins and pathogen proteins involved in the host-pathogen PPIs tend to be hubs in their own intra-species PPI network. Also, both host and pathogen proteins involved in host-pathogen PPIs tend to have longer primary sequence, tend to have more domains, tend to be more hydrophilic, etc. And the protein domains from both

  5. Advanced in-duct sorbent injection for SO{sub 2} control. Final technical report

    Energy Technology Data Exchange (ETDEWEB)

    Stouffer, M.R.; Withium, J.A.; Rosenhoover, W.A.; Maskew, J.T.

    1994-12-01

    The objective of this research project was to develop a second generation duct sorbent injection technology as a cost-effective compliance option for the 1990 Clean Air Act Amendments. Research and development work was focused on the Advanced Coolside process, which showed the potential for exceeding the original performance targets of 90% SO{sub 2} removal and 60% sorbent utilization. Process development was conducted in a 1000 acfm pilot plant. The pilot plant testing showed that the Advanced Coolside process can achieve 90% SO{sub 2} removal at sorbent utilizations up to 75%. The testing also showed that the process has the potential to achieve very high removal efficiency (90 to >99%). By conducting conceptual process design and economic evaluations periodically during the project, development work was focused on process design improvements which substantially lowered process capital and operating costs, A final process economic study projects capital costs less than one half of those for limestone forced oxidation wet FGD. Projected total SO{sub 2} control cost is about 25% lower than wet FGD for a 260 MWe plant burning a 2.5% sulfur coal. A waste management study showed the acceptability of landfill disposal; it also identified a potential avenue for by-product utilization which should be further investigated. Based on the pilot plant performance and on the above economic projections, future work to scale up the Advanced Coolside process is recommended.

  6. Pilot randomized controlled trial of individual meaning-centered psychotherapy for patients with advanced cancer.

    Science.gov (United States)

    Breitbart, William; Poppito, Shannon; Rosenfeld, Barry; Vickers, Andrew J; Li, Yuelin; Abbey, Jennifer; Olden, Megan; Pessin, Hayley; Lichtenthal, Wendy; Sjoberg, Daniel; Cassileth, Barrie R

    2012-04-20

    Spiritual well-being and sense of meaning are important concerns for clinicians who care for patients with cancer. We developed Individual Meaning-Centered Psychotherapy (IMCP) to address the need for brief interventions targeting spiritual well-being and meaning for patients with advanced cancer. Patients with stage III or IV cancer (N = 120) were randomly assigned to seven sessions of either IMCP or therapeutic massage (TM). Patients were assessed before and after completing the intervention and 2 months postintervention. Primary outcome measures assessed spiritual well-being and quality of life; secondary outcomes included anxiety, depression, hopelessness, symptom burden, and symptom-related distress. Of the 120 participants randomly assigned, 78 (65%) completed the post-treatment assessment and 67 (56%) completed the 2-month follow-up. At the post-treatment assessment, IMCP participants demonstrated significantly greater improvement than the control condition for the primary outcomes of spiritual well-being (b = 0.39; P IMCP patients were also observed for the secondary outcomes of symptom burden (b = -6.56; P IMCP group were no longer significantly greater than those observed for the TM group. IMCP has clear short-term benefits for spiritual suffering and quality of life in patients with advanced cancer. Clinicians working with patients who have advanced cancer should consider IMCP as an approach to enhance quality of life and spiritual well-being.

  7. An advanced plasma control system for the DIII-D tokamak

    Energy Technology Data Exchange (ETDEWEB)

    Ferron, J.R.; Kellman, A.; McKee, E.; Osborne, T.; Petrach, P.; Taylor, T.S.; Wight, J. [General Atomics, San Diego, CA (United States); Lazarus, E. [Oak Ridge National Lab., TN (United States)

    1991-11-01

    An advanced plasma control system is being implemented for the DIII-D tokamak utilizing digital technology. This system will regulate the position and shape of tokamak discharges that range from elongated limiter to single-null divertor and double-null divertor with elongation as high as 2.6. Development of this system is expected to lead to control system technology appropriate for use on future tokamaks such as ITER and BPX. The digital system will allow for increased precision in shape control through real time adjustment of the control algorithm to changes in the shape and discharge parameters such as {beta}{sub p}, {ell}{sub i} and scrape-off layer current. The system will be used for research on real time optimization of discharge performance for disruption avoidance, current and pressure profile control, optimization of rf antenna loading, or feedback on heat deposition patterns through divertor strike point position control, for example. Shape control with this system is based on linearization near a target shape of the controlled parameters as a function of the magnetic diagnostic signals. This digital system is unique in that it is designed to have the speed necessary to control the unstable vertical motion of highly elongated tokamak discharges such as those produced in DIII-D and planned for BPX and ITER. a 40 MHz Intel i860 processor is interfaced to up to 112 channels of analog input signals. The commands to the poloidal field coils can be updated at 80 {mu}s intervals for the control of vertical position with a delay between sampling of the analog signal and update of the command of less than 80 {mu}s.

  8. Standards and the design of the Advanced Photon Source control system

    Science.gov (United States)

    McDowell, W. P.; Knott, M. J.; Lenkszus, F. R.; Kraimer, M. R.; Daly, R. T.; Arnold, N. D.; Anderson, M. D.; Anderson, J. B.; Zieman, R. C.; Cha, Ben-Chin K.

    The Advanced Photon Source (APS), now under construction at Argonne National Laboratory is a 7 GeV positron storage ring dedicated to research facilities using synchrotron radiation. This ring, along with its injection accelerators is to be controlled and monitored with a single, flexible, and expandable control system. In the conceptual stage the control system design group faced the challenges that face all control system designers: to force the machine designers to quantify and codify the system requirements, to protect the investment in hardware and software from rapid obsolescence, and to find methods of quickly incorporating new generations of equipment and replace of obsolete equipment without disrupting the exiting system. To solve these and related problems, the APS control system group made an early resolution to use standards in the design of the system. This paper will cover the present status of the APS control system as well as discuss the design decisions which led us to use industrial standards and collaborations with other laboratories whenever possible to develop a control system. It will explain the APS control system and illustrate how the use of standards has allowed APS to design a control system whose implementation addresses these issues. The system will use high performance graphic workstations using an X-Windows Graphical User Interface at the operator interface level. It connects to VME-based microprocessors at the field level using TCP/IP protocols over high performance networks. This strategy assures the flexibility and expansibility of the control system. A defined interface between the system components will allow the system to evolve with the direct addition of future, improved equipment and new capabilities.

  9. Advanced Collaborative Emissions Study (ACES)

    Energy Technology Data Exchange (ETDEWEB)

    Greenbaum, Daniel; Costantini, Maria; Van Erp, Annemoon; Shaikh, Rashid; Bailey, Brent; Tennant, Chris; Khalek, Imad; Mauderly, Joe; McDonald, Jacob; Zielinska, Barbara; Bemis, Jeffrey; Storey, John; Hallberg, Lance; Clark, Nigel

    2013-12-31

    The objective of the Advanced Collaborative Emissions Study (ACES) was to determine before widespread commercial deployment whether or not the new, energy-efficient, heavy duty diesel engines (2007 and 2010 EPA Emissions Standards Compliant) may generate anticipated toxic emissions that could adversely affect the environment and human health. ACES was planned to take place in three phases. In Phase 1, extensive emissions characterization of four production-intent prototype engine and control systems designed to meet 2007 standards for nitrogen oxides (NOx) and particulate matter (PM) was conducted at an existing emissions characterization facility: Southwest Research Institute (SwRI). One of the tested engines was selected (at random, after careful comparison of results) for health testing in Phase 3. In Phase 2, extensive emission characterization of three production-intent prototype engine and control systems meeting the 2010 standards (including more advanced NOx controls to meet the more stringent 2010 NOx standards) was conducted at the same test facility. In Phase 3, one engine/aftertreatment system selected from Phase 1 was further characterized during health effects studies (at an existing inhalation toxicology laboratory: Lovelace Respiratory Research Institute, [LRRI]) to form the basis of the ACES safety assessment. The Department of Energy (DOE) award provided funding for emissions characterization in Phases 1 and 2 as well as exposure characterization in Phase 3. The main health analyses in Phase 3 were funded separately and are not reported here.

  10. Advanced Control of Permanent Magnet Synchronous Generators for Variable Speed Wind Energy Conversion Systems

    Science.gov (United States)

    Hostettler, Jacob

    Various environmental and economic factors have lead to increased global investment in alternative energy technologies such as solar and wind power. Although methodologies for synchronous generator control are well researched, wind turbines present control systems challenges not presented by traditional generation. The varying nature of wind makes achieving synchronism with the existing electrical power grid a greater challenge. Departing from early use of induction machines, permanent magnet synchronous generators have become the focus of power systems and control systems research into wind energy systems. This is due to their self excited nature, along with their high power density. The problem of grid synchronism is alleviated through the use of high performance power electronic converters. In achievement of the optimal levels of efficiency, advanced control systems techniques oer promise over more traditional approaches. Research into sliding mode control, and linear matrix inequalities with nite time boundedness and Hinfinity performance criteria, when applied to the dynamical models of the system, demonstrate the potential of these control methodologies as future avenues for achieving higher levels of performance and eciency in wind energy.

  11. Association between obesity and local control of advanced rectal cancer after combined surgery and radiotherapy

    Energy Technology Data Exchange (ETDEWEB)

    Choi, Yun Seon; Park, Sung Kwang; Cho, Heung Lae; Ahn, Ki Jung [Dept. of Radiation Oncology, (Korea, Republic of); Lee, Yun Han [Dept. of Molecular Medicine, Keimyung University School of Medicine, Daegu (Korea, Republic of)

    2016-06-15

    The association between metabolism and cancer has been recently emphasized. This study aimed to find the prognostic significance of obesity in advanced stage rectal cancer patients treated with surgery and radiotherapy (RT). We retrospectively reviewed the medical records of 111 patients who were treated with combined surgery and RT for clinical stage 2–3 (T3 or N+) rectal cancer between 2008 and 2014. The prognostic significance of obesity (body mass index [BMI] ≥25 kg/m{sup 2}) in local control was evaluated. The median follow-up was 31.2 months (range, 4.1 to 85.7 months). Twenty-five patients (22.5%) were classified as obese. Treatment failure occurred in 33 patients (29.7%), including local failures in 13 patients (11.7%), regional lymph node failures in 5, and distant metastases in 24. The 3-year local control, recurrence-free survival, and overall survival rates were 88.7%, 73.6%, and 87.7%, respectively. Obesity (n = 25) significantly reduced the local control rate (p = 0.045; 3-year local control, 76.2%), especially in women (n = 37, p = 0.021). Segregation of local control was best achieved by BMI of 25.6 kg/m{sup 2} as a cutoff value. Obese rectal cancer patients showed poor local control after combined surgery and RT. More effective local treatment strategies for obese patients are warranted.

  12. Advanced gate CDU control in sub-28nm node using poly slot process by scatterometry metrology

    Science.gov (United States)

    Tzai, Wei-Jhe; Chen, Howard; Lin, Jun-Jin; Huang, Yu-Hao; Yu, Chun-Chi; Lin, Ching-Hung Bert; Yoo, Sungchul; Huang, Chien-Jen Eros; Mihardja, Lanny

    2013-04-01

    Scatterometry-based metrology is a well proven method to measure and monitor the critical dimensions of interest in advanced sub-28nm process development and high volume manufacturing [1][3][4][6][7]. In this paper, a proposed solution to control and achieve the optimal gate critical dimension uniformity (CDU) was explored. The proposed solution is named a novel scatterometry slot gate CDU control flow. High performance measurement and control during the slot gate step is critical as it directly controls the poly line cut profile to the active area which then directly impacts the final device performance. The proposed flow incorporates scatterometry-based CD (SCD) measurement feedback and feed forward to the Automation Process Control (APC) system, further process recipe fine tuning utilizing the data feedback and forward, and two dimensional (2D) and three dimensional (3D) scatterometry-based CD (SCD) measurement of gate after developer inspection (ADI) and after etch inspection (AEI) [1]. The methodologies and experiment results presented in this study started from the process development through the SCD model optimization of the DOE wafers, to the final implementation of the process control flow and measurement loop into the production line to evaluate its capability for long term in-line monitoring in high volume manufacturing environment. The result showed significant improvement in the gate CD uniformity that met the sub-28nm process manufacturing requirement.

  13. Advanced Emergency Braking Control Based on a Nonlinear Model Predictive Algorithm for Intelligent Vehicles

    Directory of Open Access Journals (Sweden)

    Ronghui Zhang

    2017-05-01

    Full Text Available Focusing on safety, comfort and with an overall aim of the comprehensive improvement of a vision-based intelligent vehicle, a novel Advanced Emergency Braking System (AEBS is proposed based on Nonlinear Model Predictive Algorithm. Considering the nonlinearities of vehicle dynamics, a vision-based longitudinal vehicle dynamics model is established. On account of the nonlinear coupling characteristics of the driver, surroundings, and vehicle itself, a hierarchical control structure is proposed to decouple and coordinate the system. To avoid or reduce the collision risk between the intelligent vehicle and collision objects, a coordinated cost function of tracking safety, comfort, and fuel economy is formulated. Based on the terminal constraints of stable tracking, a multi-objective optimization controller is proposed using the theory of non-linear model predictive control. To quickly and precisely track control target in a finite time, an electronic brake controller for AEBS is designed based on the Nonsingular Fast Terminal Sliding Mode (NFTSM control theory. To validate the performance and advantages of the proposed algorithm, simulations are implemented. According to the simulation results, the proposed algorithm has better integrated performance in reducing the collision risk and improving the driving comfort and fuel economy of the smart car compared with the existing single AEBS.

  14. Effects of a stepwise multidisciplinary intervention for challenging behavior in advanced dementia: a cluster randomized controlled trial.

    NARCIS (Netherlands)

    Pieper, M.J.C.; Francke, A.L.; Steen, J.T. van der; Scherder, E.J.A.; Twisk, J.W.R.; Kovach, C.R.; Achterberg, W.P.

    2016-01-01

    Objectives: To assess whether implementation of a stepwise multicomponent intervention (STA OP!) is effective in reducing challenging behavior and depression in nursing home residents with advanced dementia. Design: Cluster randomized controlled trial. Setting: Twenty-one clusters (single

  15. Effects of a Stepwise Multidisciplinary Intervention for Challenging Behavior in Advanced Dementia: A Cluster Randomized Controlled Trial

    NARCIS (Netherlands)

    Pieper, M.J.; Francke, A.L.; Steen, J.T. van der; Scherder, E.J.; Twisk, J.W.; Kovach, C.R.; Achterberg, W.P.

    2016-01-01

    OBJECTIVES: To assess whether implementation of a stepwise multicomponent intervention (STA OP!) is effective in reducing challenging behavior and depression in nursing home residents with advanced dementia. DESIGN: Cluster randomized controlled trial. SETTING: Twenty-one clusters (single

  16. Randomized Controlled Trial of Slow Versus Rapid Enteral Feeding Advancements on the Clinical Outcomes in Very Low Birth Weight Neonates.

    Science.gov (United States)

    Ahmed, F; Mannan, M A; Dey, A C; Nahar, N; Hasan, Z; Jahan, I; Dey, S K; Shahidullah, M

    2017-04-01

    Starting and advancement of feeding in very low birth weight (VLBW) infants are big challenges for the neonatal practitioners. Wide variations in volume of feed advancement have observed in earlier trials both in slow and rapid advancement groups. Volume advancement in slow advancement groups have ranged from 10ml/kg/day to 23ml/kg/day and in rapid advancement groups have ranged from 15ml/kg/day to 45ml/kg/day in earlier different studies. This randomized controlled trial was conducted in neonatal intensive care unit (NICU) of Bangabandhu Sheikh Mujib Medical University (BSMMU) from April 2013 to July 2014 to evaluate the effects of slow versus rapid rates of feeding advancements on the clinical outcomes in very low birth weight infants. A total 95 infants were enrolled into two strata according to their birth weight. Infants of each stratum were randomly allocated to either slow or rapid advancement group during initiation of feeding. After gut priming over five days, feeding was advanced daily 10ml/kg in slow and 15ml/kg in rapid advancement group for 1000 - rapid advancement group. The primary outcome variable was time taken to achieve full enteral feed. Total 82 infants completed the trial. Demographically both groups were same. Infants in the rapid feeding advancement group achieved full enteral feedings before the slow advancement group, had significantly fewer days of parenteral nutrition and regained birth weight earlier. There were no statistical differences in episodes of feed interruption, number of infants with apnea, feed intolerance or diagnosis of sepsis. Rapid enteral feeding advancements were well tolerated by very low birth weight infants.

  17. Aeroelastic Modelling and Comparison of Advanced Active Flap Control Concepts for Load Reduction on the Upwind 5MW Wind Turbine

    NARCIS (Netherlands)

    Barlas, A.; Van Kuik, G.A.M.

    2009-01-01

    A newly developed comprehensive aeroelastic model is used to investigate active flap concepts on the Upwind 5MW reference wind turbine. The model is specially designed to facilitate distributed control concepts and advanced controller design. Different concepts of centralized and distributed control

  18. Aeroelastic modelling and comparison of advanced active flap control concepts for load reduction on the Upwind 5MW wind turbine

    NARCIS (Netherlands)

    Barlas, A.; van Kuik, G.A.M.

    2009-01-01

    A newly developed comprehensive aeroelastic model is used to investigate active flap concepts on the Upwind 5MW reference wind turbine. The model is specially designed to facilitate distributed control concepts and advanced controller design. Different concepts of centralized and distributed control

  19. Implementation of advanced feedback control algorithms for controlled resonant magnetic perturbation physics studies on EXTRAP T2R

    Science.gov (United States)

    Frassinetti, L.; Olofsson, K. E. J.; Brunsell, P. R.; Drake, J. R.

    2011-06-01

    The EXTRAP T2R feedback system (active coils, sensor coils and controller) is used to study and develop new tools for advanced control of the MHD instabilities in fusion plasmas. New feedback algorithms developed in EXTRAP T2R reversed-field pinch allow flexible and independent control of each magnetic harmonic. Methods developed in control theory and applied to EXTRAP T2R allow a closed-loop identification of the machine plant and of the resistive wall modes growth rates. The plant identification is the starting point for the development of output-tracking algorithms which enable the generation of external magnetic perturbations. These algorithms will then be used to study the effect of a resonant magnetic perturbation (RMP) on the tearing mode (TM) dynamics. It will be shown that the stationary RMP can induce oscillations in the amplitude and jumps in the phase of the rotating TM. It will be shown that the RMP strongly affects the magnetic island position.

  20. Initial Provincial Water Rights Dynamic Projection Pursuit Allocation Based on the Most Stringent Water Resources Management: A Case Study of Taihu Basin, China

    Directory of Open Access Journals (Sweden)

    Min Ge

    2017-01-01

    Full Text Available Clarification of initial water rights is the basis and prerequisite for a water rights trade-off market and also an effective solution to the problem of water scarcity and water conflicts. According to the new requirements for the most stringent water resources management in China, an initial provincial water rights allocation model is proposed. Firstly, based on analysis of multiple principles for initial provincial water rights allocation including total water use, water use efficiency, water quality of water function zones, regional coordination and sharing, an index system of initial provincial water rights allocation is designed. Secondly, according to dynamic projection pursuit technique, an initial provincial water rights allocation model with the total water use control is set up. Moreover, the self-adaptive chaotic optimization algorithm is applied to tackle the model. Finally, a case study of Taihu Basin is adopted. Considering the multiple scenarios of three different water frequencies (50%, 75% and 90% and planning year 2030, the empirical results show Jiangsu Province always obtains the most initial water rights. When the developing situation of provinces are given more consideration, Shanghai should acquire more initial water rights than Zhejiang Province; but when the dynamic increment evolving trend of provinces is taken more into account, Shanghai should obtain less initial water rights than Zhejiang Province. The case about Taihu Lake further verifies the feasibility and effectiveness of the proposed model and provides a multiple-scenarios decision making support for entitling the initial water rights with the most stringent water resources management constrains in Taihu Basin.

  1. A closed-loop photon beam control study for the Advanced Light Source

    Energy Technology Data Exchange (ETDEWEB)

    Portmann, G.; Bengtsson, J.

    1993-05-01

    The third generation Advanced Light Source (ALS) will produce extremely bright photon beams using undulators and wigglers. In order to position the photon beams accurate to the micron level, a closed-loop feedback system is being developed. Using photon position monitors and dipole corrector magnets, a closed-loop system can automatically compensate for modeling uncertainties and exogenous disturbances. The following paper will present a dynamics model for the perturbations of the closed orbit of the electron beam in the ALS storage ring including the vacuum chamber magnetic field penetration effects. Using this reference model, two closed-loop feedback algorithms will be compared -- a classical PI controller and a two degree-of-freedom approach. The two degree-of-freedom method provides superior disturbance rejection while maintaining the desired performance goals. Both methods will address the need to gain schedule the controller due to the time varying dynamics introduced by changing field strengths when scanning the insertion devices.

  2. Recent advances and challenges of fuel cell based power system architectures and control – A review

    DEFF Research Database (Denmark)

    Das, Vipin; Sanjeevikumar, Padmanaban; Venkitusamy, Karthikeyan

    2017-01-01

    Renewable energy generation is rapidly growing in the power sector industry and widely used for two categories: grid connected and standalone system. This paper gives the insights about fuel cell operation and application of various power electronics systems. The fuel cell voltage decreases bit...... of utilization. In order to improve the reliability of fuel cell based power system, the integration of energy storage system and advanced research methods are focused in this paper. The control algorithms of power architecture for the couple of well-known applications are discussed. Additionally, the paper...... addresses the suitable processor utilized as a part of the energy unit application on the premise of fuel cell characteristics. In this paper, the challenges to improve the dynamics of controller in fuel cell based applications are mentioned....

  3. Technology Reinvestment Program/Advanced ``Zero Emission'' Control Valve (Phase II)

    Energy Technology Data Exchange (ETDEWEB)

    J. Napoleon

    1998-12-01

    The objectives of this effort are to determine, develop and demonstrate the feasibility of significantly reducing the cost and expanding the applications for a family of Advanced Zero Emissions Control Valves that meets the fugitive emissions requirements of the 1990 Amendments to the Clean Air Act. This program is a direct technology spin-off from the valve technology that is critical to the US Navy's Nuclear Powered Fleet. These zero emissions valves will allow the Hydrocarbon and Chemical Processing Industries, etc., to maintain their competitiveness and still meet environmental and safety requirements. Phase 2 is directed at refining the basic technologies developed during Phase 1 so that they can be more readily selected and utilized by the target market. In addition to various necessary certifications, the project will develop a full featured digital controller with ``smart valve'' growth capability, expanding valve sizes/applications and identifying valve materials to permit applications in severe operational environments.

  4. Final Report - ADVANCED LASER-BASED SENSORS FOR INDUSTRIAL PROCESS CONTROL

    Energy Technology Data Exchange (ETDEWEB)

    Gupta, Manish; Baer, Douglas

    2013-09-30

    The objective of this work is to capture the potential of real-time monitoring and overcome the challenges of harsh industrial environments, Los Gatos Research (LGR) is fabricating, deploying, and commercializing advanced laser-based gas sensors for process control monitoring in industrial furnaces (e.g. electric arc furnaces). These sensors can achieve improvements in process control, leading to enhanced productivity, improved product quality, and reduced energy consumption and emissions. The first sensor will utilize both mid-infrared and near-infrared lasers to make rapid in-situ measurements of industrial gases and associated temperatures in the furnace off-gas. The second sensor will make extractive measurements of process gases. During the course of this DOE project, Los Gatos Research (LGR) fabricated, tested, and deployed both in-situ tunable diode laser absorption spectrometry (TDLAS) analyzers and extractive Off-Axis Integrated Cavity Output Spectroscopy (Off-Axis ICOS) analyzers.

  5. Advanced Instrumentation, Information, and Control Systems Technologies Technical Program Plan for 2014

    Energy Technology Data Exchange (ETDEWEB)

    Hallbert, Bruce [Idaho National Lab. (INL), Idaho Falls, ID (United States); Thomas, Ken [Idaho National Lab. (INL), Idaho Falls, ID (United States)

    2014-07-01

    The Advanced Instrumentation, Information, and Control (II&C) Systems Technologies Pathway conducts targeted research and development (R&D) to address aging and reliability concerns with the legacy instrumentation and control and related information systems of the U.S. operating light water reactor (LWR) fleet. This work involves two major goals: (1) to ensure that legacy analog II&C systems are not life-limiting issues for the LWR fleet, and (2) to implement digital II&C technology in a manner that enables broad innovation and business improvement in the nuclear power plant operating model. Resolving long-term operational concerns with the II&C systems contributes to the long-term sustainability of the LWR fleet, which is vital to the nation's energy and environmental security.

  6. Color deviation controlling of phosphor conformal coating by advanced spray painting technology for white LEDs.

    Science.gov (United States)

    Yang, Liang; Wang, Simin; Lv, Zhicheng; Liu, Sheng

    2013-04-01

    An advanced phosphor conformal coating technology is proposed, good correlated color temperature (CCT) and chromaticity uniformity samples are fabricated through phosphor spray painting technology. Spray painting technology is also suitable for phosphor conformal coating of whole LED wafers. The samples of different CCTs are obtained through controlling the phosphor film thickness in the range of 6-80 μm; CCT variation of samples can be controlled in the range of ±200 K. The experimental Δuv reveals that the spray painting method can obtain a much smaller CCT variation (Δuv of 1.36e(-3)) than the conventional dispensing method (Δuv of 11.86e(-3)) when the light is emitted at angles from -90° to +90°, and chromaticity area uniformity is also improved significantly.

  7. Failure to Modulate Attentional Control in Advanced Aging Linked to White Matter Pathology

    Science.gov (United States)

    Van Dijk, Koene R. A.; Shire, Emily H.; Sperling, Reisa A.; Johnson, Keith A.; Buckner, Randy L.

    2012-01-01

    Advanced aging is associated with reduced attentional control and less flexible information processing. Here, the origins of these cognitive effects were explored using a functional magnetic resonance imaging task that systematically varied demands to shift attention and inhibit irrelevant information across task blocks. Prefrontal and parietal regions previously implicated in attentional control were recruited by the task and most so for the most demanding task configurations. A subset of older individuals did not modulate activity in frontal and parietal regions in response to changing task requirements. Older adults who did not dynamically modulate activity underperformed their peers and scored more poorly on neuropsychological measures of executive function and speed of processing. Examining 2 markers of preclinical pathology in older adults revealed that white matter hyperintensities (WMHs), but not high amyloid burden, were associated with failure to modulate activity in response to changing task demands. In contrast, high amyloid burden was associated with alterations in default network activity. These results suggest failure to modulate frontal and parietal activity reflects a disruptive process in advanced aging associated with specific neuropathologic processes. PMID:21765181

  8. Demand Response Advanced Controls Framework and Assessment of Enabling Technology Costs

    Energy Technology Data Exchange (ETDEWEB)

    Potter, Jennifer; Cappers, Peter

    2017-08-28

    The Demand Response Advanced Controls Framework and Assessment of Enabling Technology Costs research describe a variety of DR opportunities and the various bulk power system services they can provide. The bulk power system services are mapped to a generalized taxonomy of DR “service types”, which allows us to discuss DR opportunities and bulk power system services in fewer yet broader categories that share similar technological requirements which mainly drive DR enablement costs. The research presents a framework for the costs to automate DR and provides descriptions of the various elements that drive enablement costs. The report introduces the various DR enabling technologies and end-uses, identifies the various services that each can provide to the grid and provides the cost assessment for each enabling technology. In addition to a report, this research includes a Demand Response Advanced Controls Database and User Manual. They are intended to provide users with the data that underlies this research and instructions for how to use that database more effectively and efficiently.

  9. Advanced Grid-Friendly Controls Demonstration Project for Utility-Scale PV Power Plants

    Energy Technology Data Exchange (ETDEWEB)

    Gevorgian, Vahan [National Renewable Energy Lab. (NREL), Golden, CO (United States); O' Neill, Barbara [National Renewable Energy Lab. (NREL), Golden, CO (United States)

    2016-01-21

    A typical photovoltaic (PV) power plant consists of multiple power electronic inverters and can contribute to grid stability and reliability through sophisticated 'grid-friendly' controls. The availability and dissemination of actual test data showing the viability of advanced utility-scale PV controls among all industry stakeholders can leverage PV's value from being simply an energy resource to providing additional ancillary services that range from variability smoothing and frequency regulation to power quality. Strategically partnering with a selected utility and/or PV power plant operator is a key condition for a successful demonstration project. The U.S. Department of Energy's (DOE's) Solar Energy Technologies Office selected the National Renewable Energy Laboratory (NREL) to be a principal investigator in a two-year project with goals to (1) identify a potential partner(s), (2) develop a detailed scope of work and test plan for a field project to demonstrate the gird-friendly capabilities of utility-scale PV power plants, (3) facilitate conducting actual demonstration tests, and (4) disseminate test results among industry stakeholders via a joint NREL/DOE publication and participation in relevant technical conferences. The project implementation took place in FY 2014 and FY 2015. In FY14, NREL established collaborations with AES and First Solar Electric, LLC, to conduct demonstration testing on their utility-scale PV power plants in Puerto Rico and Texas, respectively, and developed test plans for each partner. Both Puerto Rico Electric Power Authority and the Electric Reliability Council of Texas expressed interest in this project because of the importance of such advanced controls for the reliable operation of their power systems under high penetration levels of variable renewable generation. During FY15, testing was completed on both plants, and a large amount of test data was produced and analyzed that demonstrates the ability of

  10. Design and advanced control of switched reluctance motor; Design og avanceret styring af switched reluctance motor

    Energy Technology Data Exchange (ETDEWEB)

    Blaabjerg, F.; Jensen, F.; Kierkegaard, P.; Pedersen, J.K.; Rasmussen, P.O.; Simonsen, L.

    1999-03-01

    The aim of the project is to design, construct and optimise the control of Switched Reluctance Motors with and without permanent magnets. The expectation was an increased efficiency and a decreased material consumption. The project included originally three types of SR-motors, two with a nominal number of revolutions of 3.000 rpm and one motor with a nominal number of revolutions of 50.000 rpm. The project was changed to focus on one motor with a nominal number of revolutions of 6.000 rpm, one with a nominal number of revolutions of 50.000 rpm and one two-phased low-voltage motor with a nominal number of revolutions of 2.000 rpm. The motors had different outputs of 2,7 kW, 0,9 kW and 3 kW, respectively. For this purpose an advanced simulation programme for Switched Reluctance Motors is developed. The programme differs from other programmes by being able to simulate multi-disciplinary such as vibrations and acoustic noise. It is even possible to play the sound. In this connection completely new models are developed. It is also possible to simulate different grid connected converters. Input to the simulation programme is finite element calculations, geometry of the motor and calculations or data from an advanced characterisation system for Switched Reluctance Motors. New methods to control the current in Switched Reluctance Motors are developed, which particularly make quick dynamics possible in a digitally controlled current without use of special noise filters. The method will soon have industrial use. Other new methods have emerged, which secure that the system all the time works with the maximum efficiency irrespective of load. In some cases an efficiency improvement of 10 % is obtained compared to a classic control of the Switched Reluctance Motor. (EHS) EFP-94; EFP-95; EFP-98. 16 refs.

  11. Variable Torque Control of Offshore Wind Turbine on Spar Floating Platform Using Advanced RBF Neural Network

    Directory of Open Access Journals (Sweden)

    Lei Wang

    2014-01-01

    Full Text Available Offshore floating wind turbine (OFWT has been a challenging research spot because of the high-quality wind power and complex load environment. This paper focuses on the research of variable torque control of offshore wind turbine on Spar floating platform. The control objective in below-rated wind speed region is to optimize the output power by tracking the optimal tip-speed ratio and ideal power curve. Aiming at the external disturbances and nonlinear uncertain dynamic systems of OFWT because of the proximity to load centers and strong wave coupling, this paper proposes an advanced radial basis function (RBF neural network approach for torque control of OFWT system at speeds lower than rated wind speed. The robust RBF neural network weight adaptive rules are acquired based on the Lyapunov stability analysis. The proposed control approach is tested and compared with the NREL baseline controller using the “NREL offshore 5 MW wind turbine” model mounted on a Spar floating platform run on FAST and Matlab/Simulink, operating in the below-rated wind speed condition. The simulation results show a better performance in tracking the optimal output power curve, therefore, completing the maximum wind energy utilization.

  12. Comprehensive simulation-enhanced training curriculum for an advanced minimally invasive procedure: a randomized controlled trial.

    Science.gov (United States)

    Zevin, Boris; Dedy, Nicolas J; Bonrath, Esther M; Grantcharov, Teodor P

    2017-05-01

    There is no comprehensive simulation-enhanced training curriculum to address cognitive, psychomotor, and nontechnical skills for an advanced minimally invasive procedure. 1) To develop and provide evidence of validity for a comprehensive simulation-enhanced training (SET) curriculum for an advanced minimally invasive procedure; (2) to demonstrate transfer of acquired psychomotor skills from a simulation laboratory to live porcine model; and (3) to compare training outcomes of SET curriculum group and chief resident group. University. This prospective single-blinded, randomized, controlled trial allocated 20 intermediate-level surgery residents to receive either conventional training (control) or SET curriculum training (intervention). The SET curriculum consisted of cognitive, psychomotor, and nontechnical training modules. Psychomotor skills in a live anesthetized porcine model in the OR was the primary outcome. Knowledge of advanced minimally invasive and bariatric surgery and nontechnical skills in a simulated OR crisis scenario were the secondary outcomes. Residents in the SET curriculum group went on to perform a laparoscopic jejunojejunostomy in the OR. Cognitive, psychomotor, and nontechnical skills of SET curriculum group were also compared to a group of 12 chief surgery residents. SET curriculum group demonstrated superior psychomotor skills in a live porcine model (56 [47-62] versus 44 [38-53], Psuperior nontechnical skills (41 [38-45] versus 31 [24-40], Ptraining group. SET curriculum group and conventional training group demonstrated equivalent knowledge (14 [12-15] versus 13 [11-15], P = 0.47). SET curriculum group demonstrated equivalent psychomotor skills in the live porcine model and in the OR in a human patient (56 [47-62] versus 63 [61-68]; P = .21). SET curriculum group demonstrated inferior knowledge (13 [11-15] versus 16 [14-16]; Psuperior nontechnical skills (41 [38-45] versus 34 [27-35], Psuperior training outcomes, compared with conventional

  13. malT knockout mutation invokes a stringent type gene-expression profile in Actinobacillus pleuropneumoniae in bronchoalveolar fluid

    Directory of Open Access Journals (Sweden)

    Nash John HE

    2009-09-01

    Full Text Available Abstract Background Actinobacillus pleuropneumoniae causes contagious pleuropneumonia, an economically important disease of commercially reared pigs throughout the world. To cause this disease, A. pleuropneumoniae must rapidly overcome porcine pulmonary innate immune defenses. Since bronchoalveolar fluid (BALF contains many of the innate immune and other components found in the lungs, we examined the gene expression of a virulent serovar 1 strain of A. pleuropneumoniae after exposure to concentrated BALF for 30 min. Results In reverse transcription PCR differential display (RT-PCR DD experiments, A. pleuropneumoniae CM5 exposed to BALF up-regulated, among other genes, a gene predicted to encode LamB, an outer-membrane transport protein of the maltose regulon. To determine the role of the lamB and other genes of the maltose regulon in the pathogenesis of A. pleuropneumoniae, knockout mutations were created in the lamB and malT genes, the latter being the positive transcriptional regulator of the maltose regulon. Relative to the lamB mutant and the wild type, the malT mutant had a significant (P malT mutant exhibited a gene-expression profile resembling that of a stringent type gene-expression profile seen in bacteria facing amino acid or carbon starvation. Genes encoding proteins for protein synthesis, energy metabolism, and DNA replication were down-regulated, while genes involved in stringent response (e.g., relA, amino acid and nucleotide biosynthesis, biofilm formation, DNA transformation, and stress response were up-regulated. Conclusion These results suggest that MalT may be involved in protection against some stressors and in the transport of one or more essential nutrients in BALF. Moreover, if MalT is directly or indirectly linked to the stringent response, an important global mechanism of bacterial persistence and virulence in many bacterial pathogens, it might play a role in A. pleuropneumoniae pathogenesis.

  14. VRP immunotherapy targeting neu: treatment efficacy and evidence for immunoediting in a stringent rat mammary tumor model.

    Science.gov (United States)

    Laust, Amanda K; Sur, Brandon W; Wang, Kehui; Hubby, Bolyn; Smith, Jonathan F; Nelson, Edward L

    2007-12-01

    The ability to overcome intrinsic tolerance to a strict "self" tumor-associated antigen (TAA) and successfully treat pre-existing tumor is the most stringent test for anti-tumor immunotherapeutic strategies. Although this capacity has been demonstrated in various models using complicated strategies that may not be readily translated into the clinical arena, straightforward antigen-specific immunotherapeutic strategies in the most stringent models of common epithelial cancers have largely failed to meet this standard. We employed an immunotherapeutic strategy using an alphavirus-based, virus-like replicon particle (VRP), which has in vivo tropism for dendritic cells, to elicit immune responses to the non-mutated TAA rat neu in an aggressive rat mammary tumor model. Using this VRP-based immunotherapeutic strategy targeting a single TAA, we generated effective anti-tumor immunity in the setting of pre-existing tumor resulting in the cure of 36% of rats over multiple experiments, P = 0.002. We also observed down-regulation of rat neu expression in tumors that showed initial responses followed by tumor escape with resumption of rapid tumor growth. These responses were accompanied by significant anti-tumor proliferative responses and CD8+ cellular tumor infiltrates, all of which were restricted to animals receiving the anti-neu immunotherapy. Together these data, obtained in a stringent "self" TAA model, indicate that the VRP-based antigen-specific immunotherapy elicits sufficiently potent immune responses to exert immunologic pressure, selection, and editing of the growing tumors, thus supporting the activity of this straightforward immunotherapy and suggesting that it is a promising platform upon which to build even more potent strategies.

  15. Transcriptome analysis of Enterococcus faecalis during mammalian infection shows cells undergo adaptation and exist in a stringent response state.

    Directory of Open Access Journals (Sweden)

    Kristi L Frank

    Full Text Available As both a commensal and a major cause of healthcare-associated infections in humans, Enterococcus faecalis is a remarkably adaptable organism. We investigated how E. faecalis adapts in a mammalian host as a pathogen by characterizing changes in the transcriptome during infection in a rabbit model of subdermal abscess formation using transcriptional microarrays. The microarray experiments detected 222 and 291 differentially regulated genes in E. faecalis OG1RF at two and eight hours after subdermal chamber inoculation, respectively. The profile of significantly regulated genes at two hours post-inoculation included genes involved in stress response, metabolism, nutrient acquisition, and cell surface components, suggesting genome-wide adaptation to growth in an altered environment. At eight hours post-inoculation, 88% of the differentially expressed genes were down-regulated and matched a transcriptional profile consistent with a (pppGpp-mediated stringent response. Subsequent subdermal abscess infections with E. faecalis mutants lacking the (pppGpp synthetase/hydrolase RSH, the small synthetase RelQ, or both enzymes, suggest that intracellular (pppGpp levels, but not stringent response activation, influence persistence in the model. The ability of cells to synthesize (pppGpp was also found to be important for growth in human serum and whole blood. The data presented in this report provide the first genome-wide insights on E. faecalis in vivo gene expression and regulation measured by transcriptional profiling during infection in a mammalian host and show that (pppGpp levels affect viability of E. faecalis in multiple conditions relevant to mammalian infection. The subdermal abscess model can serve as a novel experimental system for studying the E. faecalis stringent response in the context of the mammalian immune system.

  16. Advanced sensing and control techniques to facilitate semi-autonomous decommissioning. 1998 annual progress report

    Energy Technology Data Exchange (ETDEWEB)

    Schalkoff, R.J.; Geist, R.M.; Dawson, D.M.

    1998-06-01

    'This research is intended to advance the technology of semi-autonomous teleoperated robotics as applied to Decontamination and Decommissioning (D and D) tasks. Specifically, research leading to a prototype dual-manipulator mobile work cell is underway. This cell is supported and enhanced by computer vision, virtual reality and advanced robotics technology. This report summarizes work after approximately 1.5 years of a 3-year project. The autonomous, non-contact creation of a virtual environment from an existing, real environment (virtualization) is an integral part of the workcell functionality. This requires that the virtual world be geometrically correct. To this end, the authors have encountered severe sensitivity in quadric estimation. As a result, alternative procedures for geometric rendering, iterative correction approaches, new calibration methods and associated hardware, and calibration quality examination software have been developed. Following geometric rendering, the authors have focused on improving the color and texture recognition components of the system. In particular, the authors have moved beyond first-order illumination modeling to include higher order diffuse effects. This allows us to combine the surface geometric information, obtained from the laser projection and surface recognition components of the system, with a stereo camera image. Low-level controllers for Puma 560 robotic arms were designed and implemented using QNX. The resulting QNX/PC based low-level robot control system is called QRobot. A high-level trajectory generator and application programming interface (API) as well as a new, flexible robot control API was required. Force/torque sensors and interface hardware have been identified and ordered. A simple 3-D OpenGL-based graphical Puma 560 robot simulator was developed and interfaced with ARCL and RCCL to assist in the development of robot motion programs.'

  17. Breakthrough and future: nanoscale controls of compositions, morphologies, and mesochannel orientations toward advanced mesoporous materials.

    Science.gov (United States)

    Yamauchi, Yusuke; Suzuki, Norihiro; Radhakrishnan, Logudurai; Wang, Liang

    2009-01-01

    Currently, ordered mesoporous materials prepared through the self-assembly of surfactants have attracted growing interests owing to their special properties, including uniform mesopores and a high specific surface area. Here we focus on fine controls of compositions, morphologies, mesochannel orientations which are important factors for design of mesoporous materials with new functionalities. This Review describes our recent progress toward advanced mesoporous materials. Mesoporous materials now include a variety of inorganic-based materials, for example, transition-metal oxides, carbons, inorganic-organic hybrid materials, polymers, and even metals. Mesoporous metals with metallic frameworks can be produced by using surfactant-based synthesis with electrochemical methods. Owing to their metallic frameworks, mesoporous metals with high electroconductivity and high surface areas hold promise for a wide range of potential applications, such as electronic devices, magnetic recording media, and metal catalysts. Fabrication of mesoporous materials with controllable morphologies is also one of the main subjects in this rapidly developing research field. Mesoporous materials in the form of films, spheres, fibers, and tubes have been obtained by various synthetic processes such as evaporation-mediated direct templating (EDIT), spray-dried techniques, and collaboration with hard-templates such as porous anodic alumina and polymer membranes. Furthermore, we have developed several approaches for orientation controls of 1D mesochannels. The macroscopic-scale controls of mesochannels are important for innovative applications such as molecular-scale devices and electrodes with enhanced diffusions of guest species.

  18. Advanced emissions control development project. Final report, November 1, 1993--February 29, 1996. Phase I

    Energy Technology Data Exchange (ETDEWEB)

    Farthing, G.A.

    1996-02-29

    The primary objective of the Advanced Emissions Control Development Program (AECDP) is to develop practical, cost-effective strategies for reducing the emissions of air toxics from coal-fired boilers. Ideally, the project aim is to effectively control air toxic emissions through the use of conventional flue gas cleanup equipment such as electrostatic precipitators (ESPs), fabric filters (baghouses), and wet flue gas desulfurization. B&W`s Clean Environment Development Facility (CEDF) and the AECDP equipment combined to form a state-of-the-art facility for integrated evaluation of combustion and post-combustion emissions control options. Phase I activities were primarily directed at providing a reliable, representative test facility for conducting air toxic emission control development work later in the project. This report summarizes the AECDP Phase I activities which consisted of the design, installation, shakedown, verification, and air toxics benchmarking of the AECDP facility. The AECDP facility consists of an ESP, pulse-jet baghouse, and wet scrubber. All verification and air toxic tests were conducted with a high sulfur, bituminous Ohio coal. In order to successfully apply the results of the program to utility systems, the relationship between the performance of the CEDF/AECDP test equipment and commercial units had to be established. The first step in the verification process was to validate that the flue gas treatment devices - boiler/convection pass simulator, ESP, baghouse, and wet SO{sub 2} scrubber - operate in a manner representative of commercial units.

  19. Advanced emissions control development project. Phase I, Final report, November 1, 1993--February 19, 1996

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-02-29

    The primary objective of the Advanced Emissions Control Development Program (AECDP) is to develop practical, cost-effective strategies for reducing the emissions of air toxics from coal-fired boilers. Ideally, the project aim is to effectively control air toxic emissions through the use of conventional flue gas cleanup equipment such as electrostatic precipitators (ESP`s), fabric filters (baghouse), and wet flue gas desulfurization. B&W`s Clean Environment Development Facility (CEDF) and the AECDP equipment combined to form a state-of-the-art facility for integrated evaluation of combustion and post-combustion emissions control options. Phase 1 activities were primarily aimed at providing a reliable, representative test facility for conducting air toxic emissions control development work later in the project. This report summarizes the AECDP Phase I activities which consisted of the design, installation, shakedown, verification, and air toxics benchmarking of the AECDP facility. All verification and air toxic tests were conducted with a high sulfur, bituminous Ohio coal.

  20. Building highly available control system applications with Advanced Telecom Computing Architecture and open standards

    Science.gov (United States)

    Kazakov, Artem; Furukawa, Kazuro

    2010-11-01

    Requirements for modern and future control systems for large projects like International Linear Collider demand high availability for control system components. Recently telecom industry came up with a great open hardware specification - Advanced Telecom Computing Architecture (ATCA). This specification is aimed for better reliability, availability and serviceability. Since its first market appearance in 2004, ATCA platform has shown tremendous growth and proved to be stable and well represented by a number of vendors. ATCA is an industry standard for highly available systems. On the other hand Service Availability Forum, a consortium of leading communications and computing companies, describes interaction between hardware and software. SAF defines a set of specifications such as Hardware Platform Interface, Application Interface Specification. SAF specifications provide extensive description of highly available systems, services and their interfaces. Originally aimed for telecom applications, these specifications can be used for accelerator controls software as well. This study describes benefits of using these specifications and their possible adoption to accelerator control systems. It is demonstrated how EPICS Redundant IOC was extended using Hardware Platform Interface specification, which made it possible to utilize benefits of the ATCA platform.

  1. Final LDRD report human interaction with complex systems: advances in hybrid reachability and control.

    Energy Technology Data Exchange (ETDEWEB)

    Oishi, Meeko M.

    2006-08-01

    This document describes new advances in hybrid reachability techniques accomplished during the course of a one-year Truman Postdoctoral Fellowship. These techniques provide guarantees of safety in complex systems, which is especially important in high-risk, expensive, or safety-critical systems. My work focused on new approaches to two specific problems motivated by real-world issues in complex systems: (1) multi-objective controller synthesis, and (2) control for recovery from error. Regarding the first problem, a novel application of reachability analysis allowed controller synthesis in a single step to achieve (a) safety, (b) stability, and (c) prevent input saturation. By extending the state to include the input parameters, constraints for stability, saturation, and envelope protection are incorporated into a single reachability analysis. Regarding the second problem, a new approach to the problem of recovery provides (a) states from which recovery is possible, and (b) controllers to guide the system during a recovery maneuver from an error state to a safe state in minimal time. Results are computed in both problems on nonlinear models of single longitudinal aircraft dynamics and two-aircraft lateral collision avoidance dynamics.

  2. Characterization of the tRNA and ribosome-dependent pppGpp-synthesis by recombinant stringent factor from Escherichia coli.

    Science.gov (United States)

    Knutsson Jenvert, Rose-Marie; Holmberg Schiavone, Lovisa

    2005-02-01

    Stringent factor is a ribosome-dependent ATP:GTP pyrophosphoryl transferase that synthesizes (p)ppGpp upon nutrient deprivation. It is activated by unacylated tRNA in the ribosomal amino-acyl site (A-site) but it is unclear how activation occurs. A His-tagged stringent factor was isolated by affinity-chromatography and precipitation. This procedure yielded a protein of high purity that displayed (a) a low endogenous pyrophosphoryl transferase activity that was inhibited by the antibiotic tetracycline; (b) a low ribosome-dependent activity that was inhibited by the A-site specific antibiotics thiostrepton, micrococcin, tetracycline and viomycin; (c) a tRNA- and ribosome-dependent activity amounting to 4500 pmol pppGpp per pmol stringent factor per minute. Footprinting analysis showed that stringent factor interacted with ribosomes that contained tRNAs bound in classical states. Maximal activity was seen when the ribosomal A-site was presaturated with unacylated tRNA. Less tRNA was required to reach maximal activity when stringent factor and unacylated tRNA were added simultaneously to ribosomes, suggesting that stringent factor formed a complex with tRNA in solution that had higher affinity for the ribosomal A-site. However, tRNA-saturation curves, performed at two different ribosome/stringent factor ratios and filter-binding assays, did not support this hypothesis.

  3. Mandatory Disclosure of Blockholders and Related Party Transactions : Stringent Versus Flexible Rules

    NARCIS (Netherlands)

    McCahery, J.A.; Vermeulen, E.P.M.

    2011-01-01

    Investor confidence in financial markets depends in large part on the existence of an accurate disclosure and reporting regime that provides transparency in the beneficial ownership and control structures of publicly listed companies. Today, a common post-financial crisis regulatory reform theme is

  4. Control of harmful hydrocarbon species in the exhaust of modern advanced GDI engines

    Science.gov (United States)

    Hasan, A. O.; Abu-jrai, A.; Turner, D.; Tsolakis, A.; Xu, H. M.; Golunski, S. E.; Herreros, J. M.

    2016-03-01

    A qualitative and quantitative analysis of toxic but currently non-regulated hydrocarbon compounds ranging from C5-C11, before and after a zoned three-way catalytic converter (TWC) in a modern gasoline direct injection (GDI) engine has been studied using gas chromatography-mass spectrometry (GC-MS). The GDI engine has been operated under conventional and advanced combustion modes, which result in better fuel economy and reduced levels of NOx with respect to standard SI operation. However, these fuel-efficient conditions are more challenging for the operation of a conventional TWC, and could lead to higher level of emissions released to the environment. Lean combustion leads to the reduction in pumping losses, fuel consumption and in-cylinder emission formation rates. However, lean HCCI will lead to high levels of unburnt HCs while the presence of oxygen will lower the TWC efficiency for NOx control. The effect on the catalytic conversion of the hydrocarbon species of the addition of hydrogen upstream the catalyst has been also investigated. The highest hydrocarbon engine-out emissions were produced for HCCI engine operation at low engine load operation. The catalyst was able to remove most of the hydrocarbon species to low levels (below the permissible exposure limits) for standard and most of the advanced combustion modes, except for naphthalene (classified as possibly carcinogenic to humans by the International Agency for Research on Cancer) and methyl-naphthalene (which has the potential to cause lung damage). However, when hydrogen was added upstream of the catalyst, the catalyst conversion efficiency in reducing methyl-naphthalene and naphthalene was increased by approximately 21%. This results in simultaneous fuel economy and environmental benefits from the effective combination of advanced combustion and novel aftertreatment systems.

  5. Improved Disturbance Observer (DOB) Based Advanced Feedback Control for Optimal Operation of a Mineral Grinding Process%Improved Disturbance Observer (DOB) Based Advanced Feedback Control for Optimal Operation of a Mineral Grinding Process

    Institute of Scientific and Technical Information of China (English)

    周平; 向波; 柴天佑

    2012-01-01

    Advanced feedback control for optimal operation of mineral grinding process is usually based on the model predictive control (MPC) dynamic optimization. Since the MPC does not handle disturbances directly by controller design, it cannot achieve satisfactory effects in controlling complex grinding processes in the presence of strong disturbances and large uncertainties. In this paper, an improved disturbance observer (DOB) based MPC advanced feedback control is proposed to control the multivariable grinding operation. The improved DOB is based on the optimal achievable H 2 performance and can deal with disturbance observation for the nonminimum-phase delay systems. In this DOB-MPC advanced feedback control, the higher-level optimizer computes the optimal operation points by maximize the profit function and passes them to the MPC level. The MPC acts as a presetting controller and is employed to generate proper pre-setpoint for the lower-level basic feedback control system. The DOB acts as a compensator and improves the operation performance by dynamically compensating the setpoints for the basic control system according to the observed various disturbances and plant uncertainties. Several simulations are performed to demonstrate the proposed control method for grinding process operation.

  6. Overview of Modelling and Advanced Control Strategies for Wind Turbine Systems

    Directory of Open Access Journals (Sweden)

    Silvio Simani

    2015-11-01

    Full Text Available The motivation for this paper comes from a real need to have an overview of the challenges of modelling and control for very demanding systems, such as wind turbine systems, which require reliability, availability, maintainability, and safety over power conversion efficiency. These issues have begun to stimulate research and development in the wide control community particularly for these installations that need a high degree of “sustainability”. Note that this represents a key point for offshore wind turbines, since they are characterised by expensive and/or safety critical maintenance work. In this case, a clear conflict exists between ensuring a high degree of availability and reducing maintenance times, which affect the final energy cost. On the other hand, wind turbines have highly nonlinear dynamics, with a stochastic and uncontrollable driving force as input in the form of wind speed, thus representing an interesting challenge also from the modelling point of view. Suitable control methods can provide a sustainable optimisation of the energy conversion efficiency over wider than normally expected working conditions. Moreover, a proper mathematical description of the wind turbine system should be able to capture the complete behaviour of the process under monitoring, thus providing an important impact on the control design itself. In this way, the control scheme could guarantee prescribed performance, whilst also giving a degree of “tolerance” to possible deviation of characteristic properties or system parameters from standard conditions, if properly included in the wind turbine model itself. The most important developments in advanced controllers for wind turbines are also briefly referenced, and open problems in the areas of modelling of wind turbines are finally outlined.

  7. Randomized controlled trial of standardized education and telemonitoring for pain in outpatients with advanced solid tumors.

    Science.gov (United States)

    Kim, Han Sang; Shin, Sang Joon; Kim, Sang Cheol; An, Surim; Rha, Sun Young; Ahn, Joong Bae; Cho, Byoung Chul; Choi, Hye Jin; Sohn, Joo Hyuk; Kim, Hyo Song; Chung, Hyun Cheol; Kim, Joo Hang; Roh, Jae Kyung; Lee, Soohyeon

    2013-06-01

    Previous studies have not defined the role of telemonitoring with educational tools in outpatients with advanced cancers. We tested the effectiveness of standardized education and telemonitoring for improving pain, distress, anxiety, depression, quality of life (QoL), and performance in outpatients with advanced cancers. A total of 108 patients were randomly assigned to receive pain education alone (control arm) or pain education plus telemonitoring (experimental arm). Nursing specialists provided video-assisted educational material in both arms and daily telemonitoring for the first week in the experimental arm. Assessment was performed at baseline and 1 week and included evaluations of pain (Brief Pain Inventory, BPI), distress (Distress Thermometer, DT), anxiety, and depression (Hospital Anxiety and Depression Scale, HADS), QoL (QLQ-C30), and a Karnofsky score. Overall (n = 108), pain intensity was significantly improved at 1 week, including worst pain (7.3 to 5.7, P telemonitoring plus standardized education group showed more significant improvement in portion of pain >4 on VAS scale (35% vs. 19%, P = 0.02). Standardized pain education using nursing specialists is an efficient way to improve not only pain itself but also anxiety, depression, performance, and QoL. The addition of telemonitoring helps to improve pain management in the outpatient setting.

  8. Modeling of Broadband Liners Applied to the Advanced Noise Control Fan

    Science.gov (United States)

    Nark, Douglas M.; Jones, Michael G.; Sutliff, Daniel L.

    2015-01-01

    The broadband component of fan noise has grown in relevance with an increase in bypass ratio and incorporation of advanced fan designs. Therefore, while the attenuation of fan tones remains a major factor in engine nacelle acoustic liner design, the simultaneous reduction of broadband fan noise levels has received increased interest. As such, a previous investigation focused on improvements to an established broadband acoustic liner optimization process using the Advanced Noise Control Fan (ANCF) rig as a demonstrator. Constant-depth, double-degree of freedom and variable-depth, multi-degree of freedom liner designs were carried through design, fabrication, and testing. This paper addresses a number of areas for further research identified in the initial assessment of the ANCF study. Specifically, incident source specification and uncertainty in some aspects of the predicted liner impedances are addressed. This information is incorporated in updated predictions of the liner performance and comparisons with measurement are greatly improved. Results illustrate the value of the design process in concurrently evaluating the relative costs/benefits of various liner designs. This study also provides further confidence in the integrated use of duct acoustic propagation/radiation and liner modeling tools in the design and evaluation of novel broadband liner concepts for complex engine configurations.

  9. Bridging the gap: adapting advanced display technologies for use in hybrid control rooms

    Energy Technology Data Exchange (ETDEWEB)

    Jokstad, Håkon [Inst. for Energy Technology, Halden (Norway); Boring, Ronald [Idaho National Lab. (INL), Idaho Falls, ID (United States)

    2015-02-01

    recently assisted INL in establishing the technical infrastructure for implementation of HSI prototypes from HAMMLAB into the HSSL to demonstrate relevant control room replacement systems in support of the LWRS program. In March, 2014, IFE delivered the first HSI prototype utilizing this infrastructure — a large screen overview display for INL's simulator. The co-operation now continues by developing Procedure Support Displays targeted for operators in hybrid control room settings. These prototypes are being validated with U.S. reactor operators in the HSSL and optimized to enhance their performance. This research serves as a crucial stepping stone toward incorporation of advanced display technologies into conventional main control rooms.

  10. Advanced Instrumentation and Control Methods for Small and Medium Reactors with IRIS Demonstration

    Energy Technology Data Exchange (ETDEWEB)

    J. Wesley Hines; Belle R. Upadhyaya; J. Michael Doster; Robert M. Edwards; Kenneth D. Lewis; Paul Turinsky; Jamie Coble

    2011-05-31

    Development and deployment of small-scale nuclear power reactors and their maintenance, monitoring, and control are part of the mission under the Small Modular Reactor (SMR) program. The objectives of this NERI-consortium research project are to investigate, develop, and validate advanced methods for sensing, controlling, monitoring, diagnosis, and prognosis of these reactors, and to demonstrate the methods with application to one of the proposed integral pressurized water reactors (IPWR). For this project, the IPWR design by Westinghouse, the International Reactor Secure and Innovative (IRIS), has been used to demonstrate the techniques developed under this project. The research focuses on three topical areas with the following objectives. Objective 1 - Develop and apply simulation capabilities and sensitivity/uncertainty analysis methods to address sensor deployment analysis and small grid stability issues. Objective 2 - Develop and test an autonomous and fault-tolerant control architecture and apply to the IRIS system and an experimental flow control loop, with extensions to multiple reactor modules, nuclear desalination, and optimal sensor placement strategy. Objective 3 - Develop and test an integrated monitoring, diagnosis, and prognosis system for SMRs using the IRIS as a test platform, and integrate process and equipment monitoring (PEM) and process and equipment prognostics (PEP) toolboxes. The research tasks are focused on meeting the unique needs of reactors that may be deployed to remote locations or to developing countries with limited support infrastructure. These applications will require smaller, robust reactor designs with advanced technologies for sensors, instrumentation, and control. An excellent overview of SMRs is described in an article by Ingersoll (2009). The article refers to these as deliberately small reactors. Most of these have modular characteristics, with multiple units deployed at the same plant site. Additionally, the topics focus

  11. Advanced Magnetic Metrology Instrumentation

    Institute of Scientific and Technical Information of China (English)

    2000-01-01

    The extraordinary progress in magnetic peripheral storage systems has been fueled by the ad vancements in heads (MR, GMR, spin valves) and in very high coercivity, Iow remanence thickness product (Mrt) media. These advancements are imposing new performance require ments on the magnetometers (VSMs) used to characterize these materials. At the same time, they have introduced a new paradigm for in-process (nondestructive, robotic) magnetic metrol ogy tools to assure the stringent product uniformity requirements. In this paper, we discuss the recent advancements in magnetometry for characterizing state-of-the-art media and heads, as well as other magnetic materials.

  12. Intelligent software system for the advanced control room of a nuclear power plant

    Energy Technology Data Exchange (ETDEWEB)

    Chang, Soon Heung; Choi, Seong Soo; Park, Jin Kyun; Heo, Gyung Young [Korea Advanced Institute of Science and Technology, Taejon (Korea, Republic of); Kim, Han Gon [Korea Electric Power Research Institute, Taejon (Korea, Republic of)

    1997-12-31

    The intelligent software system for nuclear power plants (NPPs) has been conceptually designed in this study. Its design goals are to operate NPPs in an improved manner and to support operators` cognitive takes. It consists of six major modules such as {sup I}nformation Processing,{sup {sup A}}larm Processing,{sup {sup P}}rocedure Tracking,{sup {sup P}}erformance Diagnosis,{sup a}nd {sup E}vent Diagnosis{sup m}odules for operators and {sup M}alfunction Diagnosis{sup m}odule for maintenance personnel. Most of the modules have been developed for several years and the others are under development. After the completion of development, they will be combined into one system that would be main parts of advanced control rooms in NPPs. 5 refs., 4 figs. (Author)

  13. Medium Access Control for Thermal Energy Harvesting in Advanced Metering Infrastructures

    DEFF Research Database (Denmark)

    Vithanage, Madava D.; Fafoutis, Xenofon; Andersen, Claus Bo

    2013-01-01

    In this paper we investigate the feasibility of powering wireless metering devices, namely heat cost allocators, by thermal energy harvested from radiators. The goal is to take a first step toward the realization of Energy-Harvesting Advanced Metering Infrastructures (EH-AMIs). While traditional...... battery-powered devices have a limited amount of energy, energy harvesting can potentially provide an infinite amount of energy for continuous operating lifetimes, thus reducing the cost involved in installation and maintenance. The contribution of this work is twofold. First, we experimentally identify...... the potential energy that can be harvested from Low Surface Temperature (LST) radiators. The experiments are based on a developed Energy-Harvesting Heat Cost Allocator (EH-HCA) prototype. On the basis of this measured power budget, we model and analytically compare the currently used Medium Access Control (MAC...

  14. The Chimera II Real-Time Operating System for advanced sensor-based control applications

    Science.gov (United States)

    Stewart, David B.; Schmitz, Donald E.; Khosla, Pradeep K.

    1992-01-01

    Attention is given to the Chimera II Real-Time Operating System, which has been developed for advanced sensor-based control applications. The Chimera II provides a high-performance real-time kernel and a variety of IPC features. The hardware platform required to run Chimera II consists of commercially available hardware, and allows custom hardware to be easily integrated. The design allows it to be used with almost any type of VMEbus-based processors and devices. It allows radially differing hardware to be programmed using a common system, thus providing a first and necessary step towards the standardization of reconfigurable systems that results in a reduction of development time and cost.

  15. Overcoming the Pigou-Downs Paradox Using Advanced Traffic Signal Control

    Science.gov (United States)

    Fowdur, S. C.; Rughooputh, S. D. D. V.

    2013-06-01

    Expansion of a road network has often been observed to cause more congestion and has led researchers to the formulation of traffic paradoxes such as the Pigou-Downs and the Braess paradoxes. In this paper, we present an application of advanced traffic signal control (ATSC) to overcome the Pigou-Downs paradox. Port Louis, the capital city of Mauritius is used to investigate the effect of using a harbor bridge to by-pass the city center. Using traffic cellular automata (TCA) simulations it has been shown how, if traffic is only gradually deviated along the by-pass, an overall longer travel time and decreased flux would result. By making use of ATSC, which involves traffic lights that sense the number of vehicles accumulated in the queue, better travel times and fluxes are achieved.

  16. Research relative to an advanced rod control system for quadrupole mass spectrometry applications

    Science.gov (United States)

    Carignan, George R.

    1987-01-01

    The design of a suitable amplifier output stage using available transistors and passive components is summarized. All of the analysis and calculation confirm that it is feasible to design the amplifier and quadrupole coupling circuit needed for the Advanced Rod Control System. The progress obtained so far concerning the three frequency tank circuits to be used in the oscillator for the mass spectrometer of the Cometary Rendezvous Asteroid Flyby (CRAF) project is presented. Results from this study look promising. However, it is not known what minimum impedance levels are required to make it possible for the oscillator to work properly. Therefore, it is necessary to construct a prototype circuit in the laboratory which can be measured and tested in an oscillator circuit. Continued attempts will be made to develop a useful inductor motor with better characteristics than the one being used at the moment. It is important that such a model be found if computer simulation is to reflect reality more closely.

  17. Examining the role of gender in career advancement at the Centers for Disease Control and Prevention.

    Science.gov (United States)

    Chen, Zhuo; Roy, Kakoli; Gotway Crawford, Carol A

    2010-03-01

    During the past decade, efforts to promote gender parity in the healing and public health professions have met with only partial success. We provide a critical update regarding the status of women in the public health profession by exploring gender-related differences in promotion rates at the nation's leading public health agency, the Centers for Disease Control and Prevention (CDC). Using personnel data drawn from CDC, we found that the gender gap in promotion has diminished across time and that this reduction can be attributed to changes in individual characteristics (e.g., higher educational levels and more federal work experience). However, a substantial gap in promotion that cannot be explained by such characteristics has persisted, indicating continuing barriers in women's career advancement.

  18. DOE Advanced Controls R&D Planning Workshop, June 11, 2003, Washington DC: Workshop Results

    Energy Technology Data Exchange (ETDEWEB)

    Brambley, Michael R.; Haves, Philip; McDonald, Sean C.; Torcellini, Paul; Hansen, David G.; Holmberg, David; Roth, Kurt

    2005-04-13

    On June 11, 2003, representatives from universities, federal and state government agencies, Department of Energy national laboratories, and the private sector attended a one-day workshop in Washington, DC. The objective of the workshop was to review and provide input into DOE's assessment of the market for advanced sensors and controls technology and potential R&D pathways to enhance their success in the buildings market place. The workshop consisted of two sessions. During the morning session, participants were given an overview on the following topics: market assessment, current applications and strategies for new applications, sensors and controls, networking, security, and protocols and standards, and automated diagnostics, performance measurement, commissioning and optimal control and tools. In the sessions, workshop participants were asked to review the potential R&D pathways, identify high priority activities, and outline a five year path for each of these activities. Priorities were as follows: largest and quickest impact; best use of finite resources; greatest likelihood for market penetration; and ability to replicate results. The participants identified several promising R&D opportunities.

  19. DOE Advanced Controls R&D Planning Workshop, June 11, 2003, Washington DC: Workshop Results

    Energy Technology Data Exchange (ETDEWEB)

    Brambley, Michael R.; Haves, Philip; McDonald, Sean C.; Torcellini, Paul; Hansen, David G.; Holmberg, David; Roth, Kurt

    2005-04-13

    On June 11, 2003, representatives from universities, federal and state government agencies, Department of Energy national laboratories, and the private sector attended a one-day workshop in Washington, DC. The objective of the workshop was to review and provide input into DOE's assessment of the market for advanced sensors and controls technology and potential R&D pathways to enhance their success in the buildings market place. The workshop consisted of two sessions. During the morning session, participants were given an overview on the following topics: market assessment, current applications and strategies for new applications, sensors and controls, networking, security, and protocols and standards, and automated diagnostics, performance measurement, commissioning and optimal control and tools. In the sessions, workshop participants were asked to review the potential R&D pathways, identify high priority activities, and outline a five year path for each of these activities. Priorities were as follows: largest and quickest impact; best use of finite resources; greatest likelihood for market penetration; and ability to replicate results. The participants identified several promising R&D opportunities.

  20. The stringent factor RelA adopts an open conformation on the ribosome to stimulate ppGpp synthesis.

    Science.gov (United States)

    Arenz, Stefan; Abdelshahid, Maha; Sohmen, Daniel; Payoe, Roshani; Starosta, Agata L; Berninghausen, Otto; Hauryliuk, Vasili; Beckmann, Roland; Wilson, Daniel N

    2016-07-27

    Under stress conditions, such as nutrient starvation, deacylated tRNAs bound within the ribosomal A-site are recognized by the stringent factor RelA, which converts ATP and GTP/GDP to (p)ppGpp. The signaling molecules (p)ppGpp globally rewire the cellular transcriptional program and general metabolism, leading to stress adaptation. Despite the additional importance of the stringent response for regulation of bacterial virulence, antibiotic resistance and persistence, structural insight into how the ribosome and deacylated-tRNA stimulate RelA-mediated (p)ppGpp has been lacking. Here, we present a cryo-EM structure of RelA in complex with the Escherichia coli 70S ribosome with an average resolution of 3.7 Å and local resolution of 4 to >10 Å for RelA. The structure reveals that RelA adopts a unique 'open' conformation, where the C-terminal domain (CTD) is intertwined around an A/T-like tRNA within the intersubunit cavity of the ribosome and the N-terminal domain (NTD) extends into the solvent. We propose that the open conformation of RelA on the ribosome relieves the autoinhibitory effect of the CTD on the NTD, thus leading to stimulation of (p)ppGpp synthesis by RelA.

  1. Advanced Manufacturing for Thermal and Environmental Control Systems: Achieving National Energy Goals

    Energy Technology Data Exchange (ETDEWEB)

    Bogucz, Edward A. [Syracuse Univ., NY (United States)

    2017-02-20

    This project was part of a regional initiative in the five counties of Central New York (CNY) that received funding from the U.S. Department of Energy (DOE) and four other federal agencies through the 2012 Advanced Manufacturing Jobs and Innovation Accelerator Challenge (AMJIAC). The CNY initiative was focused on cultivating the emergent regional cluster in “Advanced Manufacturing for Thermal and Environmental Control (AM-TEC).” As one component of the CNY AM-TEC initiative, the DOE-funded project supported five research & development seed projects that strategically targeted: 1) needs and opportunities of CNY AM-TEC companies, and 2) the goal of DOE’s Advanced Manufacturing Office (AMO) to reduce energy consumption by 50% across product life-cycles over 10 years. The project also sought to fulfill the AMO mission of developing and demonstrating new, energy-efficient processing and materials technologies at a scale adequate to prove their value to manufacturers and spur investment. The five seed projects demonstrated technologies and processes that can reduce energy intensity and improve production as well as use less energy throughout their lifecycles. The project was conducted over three years in two 18-month budget periods. During the first budget period, two projects proposed in the original AMJAIC application were successfully completed: Seed Project 1 focused on saving energy in heat transfer processes via development of nano structured surfaces to significantly increase heat flux; Seed Project 2 addressed saving energy in data centers via subzero cooling of the computing processors. Also during the first budget period, a process was developed and executed to select a second round of seed projects via a competitive request for proposals from regional companies and university collaborators. Applicants were encouraged to form industry-academic partnerships to leverage experience and resources of public and private sectors in the CNY region. Proposals were

  2. Having a goal to stop action is associated with advance control of specific motor representations.

    Science.gov (United States)

    Claffey, Michael P; Sheldon, Sarah; Stinear, Cathy M; Verbruggen, Frederick; Aron, Adam R

    2010-01-01

    An important aspect of cognitive control consists in the ability to stop oneself from making inappropriate responses. In an earlier study we demonstrated that there are different mechanisms for stopping: global and selective [Aron, A. R., Verbruggen, F. (2008). Stop the presses: Dissociating a selective from a global mechanism for stopping. Psychological Science, 19(11) 1146-1153]. We argued that participants are more likely to use a global mechanism when speed is of the essence, whereas they are more likely to use a selective mechanism when they have foreknowledge of which response tendency they may need to stop. Here we further investigate the relationship between foreknowledge and selective stopping. In Experiment 1 we adapted the earlier design to show that individual differences in recall accuracy for the stopping goal correlate with the selectivity of the stopping. This confirms that encoding and using a foreknowledge memory cue is a key enabler for a selective stopping mechanism. In Experiment 2, we used transcranial magnetic stimulation (TMS), to test the hypothesis that foreknowledge "sets up" a control set whereby control is applied onto the response representation that may need to be stopped in the future. We applied TMS to the left motor cortex and measured motor evoked potentials (MEPs) from the right hand while participants performed a similar behavioral paradigm as Experiment 1. In the foreknowledge period, MEPs were significantly reduced for trials where the right hand was the one that might need to be stopped relative to when it was not. This shows that having a goal of what response may need to be stopped in the future consists in applying advance control onto a specific motor representation.

  3. Advanced Communication and Control of Distributed Energy Resources at Detroit Edison

    Energy Technology Data Exchange (ETDEWEB)

    Haukur Asgeirsson; Richard Seguin

    2004-01-31

    (Utility) led team, which also includes: DTE Energy Technology (DER provider & Aggregator), Electrical Distribution Design (Virginia Tech company supporting DEW); Systems Integration Specialists Company (real-time protocol integrator); and OSIsoft (software system for managing real-time information). This work was performed in anticipation of being selected for Phase II of the Advanced Communication and Control of Distributed Energy Resources project.

  4. Infrared spectroscopy for process control and fault detection of advanced semiconductor processes

    Science.gov (United States)

    Rosenthal, P.; Aarts, W.; Bonanno, A.; Boning, D.; Charpenay, S.; Gower, A.; Richter, M.; Smith, T.; Solomon, P.; Spartz, M.; Nelson, C.; Waldhauer, A.; Xu, J.; Yakovlev, V.; Zhang, W.; Allen, L.; Cordts, B.; Brandt, M.; Mundt, R.; Perry, A.

    1998-11-01

    Fourier transform infrared (FTIR) spectroscopy has emerged as an attractive sensor for in-situ monitoring and control of semiconductor fabrication processes. New applications are being enabled by advances in FTIR hardware and software that provide for: compact size, fast measurements with exceptional stability and signal to noise, and intelligent model based algorithms for thin film and gas analysis. In previously reported work, FTIR instrumentation with automated spectral analysis software was demonstrated as a novel sensor for monitoring layer properties such as thickness, composition and temperature. Recent work has emphasized applications to practical problems in modern semiconductor manufacturing. In this paper we will report pioneering results on: 1) Run-to-run closed loop control of a single wafer epitaxial silicon process using integrated infrared thickness and doping profiling metrology, 2) Fault detection during cluster tool plasma etching using real-time infrared exhaust gas analysis, and 3) oxygen implantation process monitoring during the formation of silicon on insulator (SOI) wafers using infrared reflectometry.

  5. Advanced international training course on state systems of accounting for and control of nuclear materials

    Energy Technology Data Exchange (ETDEWEB)

    1981-10-01

    This report incorporates all lectures and presentations at the Advanced International Training Course on State Systems of Accounting for and Control of Nuclear Material held April 27 through May 12, 1981 at Santa Fe and Los Alamos, New Mexico, and Richland, Washington, USA. Authorized by the US Nuclear Non-Proliferation Act and sponsored by the US Department of Energy in cooperation with the International Atomic Energy Agency, the course was developed to provide practical training in the design, implementation, and operation of a state system of nuclear materials accountability and control that satisfies both national and international safeguards. Major emphasis for the 1981 course was placed on safeguards methods used at bulk-handling facilities, particularly low-enriched uranium conversion and fuel fabrication plants. The course was conducted by the University of California's Los Alamos National Laboratory, the Battelle Pacific Northwest Laboratory, and Exxon Nuclear Company, Inc. Tours and demonstrations were arranged at both the Los Alamos National Laboratory, Los Alamos, New Mexico, and the Exxon Nuclear fuel fabrication plant, Richland, Washington.

  6. Optical techniques for signal distribution and control in advanced radar and communication systems

    Science.gov (United States)

    Forrest, J. R.

    1985-03-01

    It is concluded that optical techniques offer some advantages for signal distribution and control in advanced radar and communication systems. They are clearly ideal for transporting microwave signals over considerable distances, as in remote positioning of radar receivers, provided high dynamic range is not required and an enclosed transmission path is essential. They are an elegant means of distributing low level r.f. or i.f. signals around an active phased array where these signals are of relatively constant amplitude (as in mixer local oscillator applications). However, there is currently a rather restrictive limit on the size of distribution network possible. Optical techniques are obviously suitable for distributing digital control signals to phased array modules and confer considerable immunity to interference. They are less suitable for high dynamic range signals, such as the received radar returns, either at r.f. or when downcovered to i.f. Future developments in coherent optics or in fast optical A/D technology could, however, influence this conclusion. Currently, the optimum applications for optical techniques appear to be i.f. beamformers for multibeam communication satellite systems and in calibration/monitoring systems for phased arrays.

  7. Production of potato minitubers using advanced environmental control technologies developed for growing plants in space

    Science.gov (United States)

    Britt, Robert G.

    1998-01-01

    Development of plant growth systems for use in outer space have been modified for use on earth as the backbone of a new system for rapid growth of potato minitubers. The automation of this new biotechnology provides for a fully controllable method of producing pathogen-free nuclear stock potato minitubers from tissue cultured clones of varieties of potato in a biomanufacturing facility. These minitubers are the beginning stage of seed potato production. Because the new system provides for pathogen-free minitubers by the tens-of-millions, rather than by the thousands which are currently produced in advanced seed potato systems, a new-dimension in seed potato development, breeding and multiplication has been achieved. The net advantage to earth-borne agricultural farming systems will be the elimination of several years of seed multiplication from the current system, higher quality potato production, and access to new potato varieties resistant to diseases and insects which will eliminate the need for chemical controls.

  8. Improving the efficiency of advanced life support training: a randomized, controlled trial.

    Science.gov (United States)

    Perkins, Gavin D; Kimani, Peter K; Bullock, Ian; Clutton-Brock, Tom; Davies, Robin P; Gale, Mike; Lam, Jenny; Lockey, Andrew; Stallard, Nigel

    2012-07-03

    Each year, more than 1.5 million health care professionals receive advanced life support (ALS) training. To determine whether a blended approach to ALS training that includes electronic learning (e-learning) produces outcomes similar to those of conventional, instructor-led ALS training. Open-label, noninferiority, randomized trial. Randomization, stratified by site, was generated by Sealed Envelope (Sealed Envelope, London, United Kingdom). (International Standardized Randomized Controlled Trial Number Register: ISCRTN86380392) 31 ALS centers in the United Kingdom and Australia. 3732 health care professionals recruited between December 2008 and October 2010. A 1-day course supplemented with e-learning versus a conventional 2-day course. The primary outcome was performance in a cardiac arrest simulation test at the end of the course. Secondary outcomes comprised knowledge- and skill-based assessments, repeated assessment after remediation training, and resource use. 440 of the 1843 participants randomly assigned to the blended course and 444 of the 1889 participants randomly assigned to conventional training did not attend the courses. Performance in the cardiac arrest simulation test after course attendance was lower in the electronic advanced life support (e-ALS) group compared with the conventional advanced life support (c-ALS) group; 1033 persons (74.5%) in the e-ALS group and 1146 persons (80.2%) in the c-ALS group passed (mean difference, -5.7% [95% CI, -8.8% to -2.7%]). Knowledge- and skill-based assessments were similar between groups, as was the final pass rate after remedial teaching, which was 94.2% in the e-ALS group and 96.7% in the c-ALS group (mean difference, -2.6% [CI, -4.1% to 1.2%]). Faculty, catering, and facility costs were $438 per participant for electronic ALS training and $935 for conventional ALS training. Many professionals (24%) did not attend the courses. The effect on patient outcomes was not evaluated. Compared with conventional ALS

  9. Investigation on the design of human-system interface for advanced nuclear plant control room

    Energy Technology Data Exchange (ETDEWEB)

    Chuang, C. F.; Chou, H. P. [Dept. of Engineering and System Science, National Tsing Hua Univ., Hsinchu Taiwan (China)

    2006-07-01

    The Lungmen Nuclear Power Project (LMNPP), under construction in Taiwan, consists of two GE Advanced Boiling Water Reactor (ABWR) units, each with 1350 MW electrical output. Major Human-System Interfaces (HSIs) of LMNPP are different from traditional ones. Video display units (VDUs) are the main human-system interface for operators to manipulate and to know the status of the equipment and plant information. Based upon NUREG-0711, the applicable human factors engineering (HFE) guideline in the design of HSIs has been adopted. An important aspect of the Lungmen HFE program has been the direct involvement of the end user, Taiwan Power Company (TPC), throughout the design development and implementation to ensure not only that the process for the design is compliant with the HFE principles, but also that the necessary displays, control, and alarms are provided to support the identified personnel tasks. This paper reviews the applicable HFE principles and verification and validation (V and V) processes in the design of HSIs for the advanced LMNPP. This paper also presents three investigated topics of the LMNPP HSI design development and implementation process. From the perspective of licensing concern and experience feedback, the focus of this paper is on the topics of validation with simulator, alarm auto reset, and VDU operational configuration strategy. The objectives of investigating the latter topic were to ensure the VDU operational configuration strategy, after appropriate V and V, achieves its goals of reinforcing operation discipline and distributing operator crew task assignments and workload during typical operations, and to confirm the need for an intensive training program that addresses the knowledge and skill requirements of the operators to meet the task characteristics and the responses of the plant processes. The results to date and implications for going forward from this process are also presented. (authors)

  10. Advanced Communication and Control for Distributed Energy Resource Integration: Phase 2 Scientific Report

    Energy Technology Data Exchange (ETDEWEB)

    BPL Global

    2008-09-30

    The objective of this research project is to demonstrate sensing, communication, information and control technologies to achieve a seamless integration of multivendor distributed energy resource (DER) units at aggregation levels that meet individual user requirements for facility operations (residential, commercial, industrial, manufacturing, etc.) and further serve as resource options for electric and natural gas utilities. The fully demonstrated DER aggregation system with embodiment of communication and control technologies will lead to real-time, interactive, customer-managed service networks to achieve greater customer value. Work on this Advanced Communication and Control Project (ACCP) consists of a two-phase approach for an integrated demonstration of communication and control technologies to achieve a seamless integration of DER units to reach progressive levels of aggregated power output. Phase I involved design and proof-of-design, and Phase II involves real-world demonstration of the Phase I design architecture. The scope of work for Phase II of this ACCP involves demonstrating the Phase I design architecture in large scale real-world settings while integrating with the operations of one or more electricity supplier feeder lines. The communication and control architectures for integrated demonstration shall encompass combinations of software and hardware components, including: sensors, data acquisition and communication systems, remote monitoring systems, metering (interval revenue, real-time), local and wide area networks, Web-based systems, smart controls, energy management/information systems with control and automation of building energy loads, and demand-response management with integration of real-time market pricing. For Phase II, BPL Global shall demonstrate the Phase I design for integrating and controlling the operation of more than 10 DER units, dispersed at various locations in one or more Independent System Operator (ISO) Control Areas, at

  11. IEDA Thesaurus: A Controlled Vocabulary for IEDA Systems to Advance Integration

    Science.gov (United States)

    Ji, P.; Lehnert, K. A.; Arko, R. A.; Song, L.; Hsu, L.; Carter, M. R.; Ferrini, V. L.; Ash, J.

    2014-12-01

    Integrated Earth Data Applications (IEDA) is a community-based facility that serves to support, sustain, and advance the geosciences by providing data services for observational geoscience data from the Ocean, Earth, and Polar Sciences. Many dedicated systems such as the Petrological Database (PetDB), Marine Geoscience Data System (MGDS), System for Earth Sample Registration (SESAR), Data Coordination Center for the U.S. Antarctic Program (USAP-DCC), etc., under the umbrella of the IEDA framework, were developed to support the preservation, discovery, retrieval, and analysis of a wide range of observational field and analytical data types from diverse communities. However, it is currently difficult to maintain consistency of indexing content within IEDA schema, and perform unified or precise searching of the data in these diverse systems as each system maintains separate vocabularies, hierarchies, authority files, or sub taxonomies. We present here the IEDA Thesaurus, a system, which combines existing separate controlled vocabularies from the different systems under the IEDA schema into a single master controlled vocabulary, also introducing some new top facets for future long-term use. The IEDA thesaurus contains structured terminology for petrology, geochemistry, sedimentology, oceanography, geochronology, and volcanology, and other general metadata fields. 18 top facets (also called 'top categories') are defined, including equipment, geographic gazetteer, geologic ages, geologic units, materials, etc. The terms of the thesaurus are cross validated with others popular geoscience vocabularies such as GeoRef Thesaurus, U.S. Geological Survey Library Classification System, Global Change Master Directory (GCMD), and Semantic Web for Earth and Environmental Terminology (SWEET) ontologies. The thesaurus is organized along with the ANSI/NISO Z39.19-2005 Guidelines for the Construction, Format, and Management of Monolingual Controlled Vocabularies, and is published using

  12. The mechanism of heterogeneous beta-lactam resistance in MRSA: key role of the stringent stress response.

    Directory of Open Access Journals (Sweden)

    Choonkeun Kim

    Full Text Available All methicillin resistant S. aureus (MRSA strains carry an acquired genetic determinant--mecA or mecC--which encode for a low affinity penicillin binding protein -PBP2A or PBP2A'--that can continue the catalysis of peptidoglycan transpeptidation in the presence of high concentrations of beta-lactam antibiotics which would inhibit the native PBPs normally involved with the synthesis of staphylococcal cell wall peptidoglycan. In contrast to this common genetic and biochemical mechanism carried by all MRSA strains, the level of beta-lactam antibiotic resistance shows a very wide strain to strain variation, the mechanism of which has remained poorly understood. The overwhelming majority of MRSA strains produce a unique--heterogeneous--phenotype in which the great majority of the bacteria exhibit very poor resistance often close to the MIC value of susceptible S. aureus strains. However, cultures of such heterogeneously resistant MRSA strains also contain subpopulations of bacteria with extremely high beta-lactam MIC values and the resistance level and frequency of the highly resistant cells in such strain is a characteristic of the particular MRSA clone. In the study described in this communication, we used a variety of experimental models to understand the mechanism of heterogeneous beta-lactam resistance. Methicillin-susceptible S. aureus (MSSA that received the mecA determinant in the laboratory either on a plasmid or in the form of a chromosomal SCCmec cassette, generated heterogeneously resistant cultures and the highly resistant subpopulations that emerged in these models had increased levels of PBP2A and were composed of bacteria in which the stringent stress response was induced. Each of the major heterogeneously resistant clones of MRSA clinical isolates could be converted to express high level and homogeneous resistance if the growth medium contained an inducer of the stringent stress response.

  13. The Project ENABLE II Randomized Controlled Trial to Improve Palliative Care for Patients with Advanced Cancer

    Science.gov (United States)

    Bakitas, Marie; Lyons, Kathleen Doyle; Hegel, Mark T.; Balan, Stefan; Brokaw, Frances C.; Seville, Janette; Hull, Jay G.; Li, Zhongze; Tosteson, Tor; Byock, Ira R.; Ahles, Tim A.

    2013-01-01

    Context There are few randomized controlled trials of the effectiveness of palliative care. Objective To determine the effect of a palliative care intervention on quality of life (QOL), symptom intensity, mood, and resource utilization. Design, Setting, and Participants Randomized controlled trial (November 2003-May 2008) of 322 patients with advanced cancer and an identified caregiver in a rural, NCI-designated comprehensive cancer center (the Norris Cotton Cancer Center, Lebanon, NH) and affiliated outreach clinics and Veteran’s Affairs Medical Center (White River Junction, VT). Intervention A multi-component, psycho-educational, palliative care intervention (Project ENABLE) conducted by an advanced practice nurse consisting of 4 weekly educational sessions and monthly follow-up until death or study completion. Main Outcome Measures (1) The Functional Assessment of Chronic Illness Therapy-Palliative (range: 0 to 184; higher scores indicate better QOL), (2) Edmonton Symptom Assessment Scale (range: 0 to 900; higher scores indicate greater symptom intensity), (3) Center for Epidemiological Studies-Depression (range: 0 to 60; higher scores indicate more depressive symptoms), completed at baseline, 1 month and every 3 months until death or study completion, (4) days in hospital, intensive care unit (ICU), and emergency department visits recorded in the medical record. Results 322 participants with gastrointestinal (41%), lung (36%), genitourinary (12%), and breast (10%) cancer were randomized. Estimated treatment effects (intervention minus usual care) for all subjects were 4.6 (P = .02) for QOL, −27.8 (P = .06) for symptom intensity, and −1.8 (P = .02) for depressed mood. Estimated average treatment effects in the sample of participants who died during the study were 8.6 (P = .02) for QOL, −24.2 (P = .24) for symptom intensity, and −2.7 (P = .03) for depressed mood. Days in hospital, intensive care unit, and emergency department visits were not different

  14. An Advanced Electrospinning Method of Fabricating Nanofibrous Patterned Architectures with Controlled Deposition and Desired Alignment

    Science.gov (United States)

    Rasel, Sheikh Md

    We introduce a versatile advanced method of electrospinning for fabricating various kinds of nanofibrous patterns along with desired alignment, controlled amount of deposition and locally variable density into the architectures. In this method, we employed multiple electrodes whose potentials have been altered in milliseconds with the help of microprocessor based control system. Therefore, key success of this method was that the electrical field as well as charge carrying fibers could be switched shortly from one electrode's location to another, as a result, electrospun fibers could be deposited on the designated areas with desired alignment. A wide range of nanofibrous patterned architectures were constructed using proper arrangement of multiple electrodes. By controlling the concurrent activation time of two adjacent electrodes, we demonstrated that amount of fibers going into the pattern can be adjusted and desired alignment in electrospun fibers can be obtained. We also revealed that the deposition density of electrospun fibers in different areas of patterned architectures can be varied. We showed that by controlling the deposition time between two adjacent electrodes, a number of functionally graded patterns can be generated with uniaxial alignment. We also demonstrated that this handy method was capable of producing random, aligned, and multidirectional nanofibrous mats by engaging a number of electrodes and switching them in desired patterns. A comprehensive study using finite element method was carried out to understand the effects of electrical field. Simulation results revealed that electrical field strength alters shortly based on electrode control switch patterns. Nanofibrous polyvinyl alcohol (PVA) scaffolds and its composite reinforced with wollastonite and wood flour were fabricated using rotating drum electrospinning technique. Morphological, mechanical, and thermal, properties were characterized on PVA/wollastonite and PVA/wood flour nanocomposites

  15. Advanced Instrumentation and Control Methods for Small and Medium Reactors with IRIS Demonstration

    Energy Technology Data Exchange (ETDEWEB)

    J. Wesley Hines; Belle R. Upadhyaya; J. Michael Doster; Robert M. Edwards; Kenneth D. Lewis; Paul Turinsky; Jamie Coble

    2011-05-31

    Development and deployment of small-scale nuclear power reactors and their maintenance, monitoring, and control are part of the mission under the Small Modular Reactor (SMR) program. The objectives of this NERI-consortium research project are to investigate, develop, and validate advanced methods for sensing, controlling, monitoring, diagnosis, and prognosis of these reactors, and to demonstrate the methods with application to one of the proposed integral pressurized water reactors (IPWR). For this project, the IPWR design by Westinghouse, the International Reactor Secure and Innovative (IRIS), has been used to demonstrate the techniques developed under this project. The research focuses on three topical areas with the following objectives. Objective 1 - Develop and apply simulation capabilities and sensitivity/uncertainty analysis methods to address sensor deployment analysis and small grid stability issues. Objective 2 - Develop and test an autonomous and fault-tolerant control architecture and apply to the IRIS system and an experimental flow control loop, with extensions to multiple reactor modules, nuclear desalination, and optimal sensor placement strategy. Objective 3 - Develop and test an integrated monitoring, diagnosis, and prognosis system for SMRs using the IRIS as a test platform, and integrate process and equipment monitoring (PEM) and process and equipment prognostics (PEP) toolboxes. The research tasks are focused on meeting the unique needs of reactors that may be deployed to remote locations or to developing countries with limited support infrastructure. These applications will require smaller, robust reactor designs with advanced technologies for sensors, instrumentation, and control. An excellent overview of SMRs is described in an article by Ingersoll (2009). The article refers to these as deliberately small reactors. Most of these have modular characteristics, with multiple units deployed at the same plant site. Additionally, the topics focus

  16. DOE Project: Optimization of Advanced Diesel Engine Combustion Strategies "University Research in Advanced Combustion and Emissions Control" Office of FreedomCAR and Vehicle Technologies Program

    Energy Technology Data Exchange (ETDEWEB)

    Reitz, Rolf; Foster, D.; Ghandhi, J.; Rothamer, D.; Rutland, C.; Sanders, S.; Trujillo, M.

    2012-10-26

    The goal of the present technology development was to increase the efficiency of internal combustion engines while minimizing the energy penalty of meeting emissions regulations. This objective was achieved through experimentation and the development of advanced combustion regimes and emission control strategies, coupled with advanced petroleum and non-petroleum fuel formulations. To meet the goals of the project, it was necessary to improve the efficiency of expansion work extraction, and this required optimized combustion phasing and minimized in-cylinder heat transfer losses. To minimize fuel used for diesel particulate filter (DPF) regeneration, soot emissions were also minimized. Because of the complex nature of optimizing production engines for real-world variations in fuels, temperatures and pressures, the project applied high-fidelity computing and high-resolution engine experiments synergistically to create and apply advanced tools (i.e., fast, accurate predictive models) developed for low-emission, fuel-efficient engine designs. The companion experiments were conducted using representative single- and multi-cylinder automotive and truck diesel engines.

  17. Efficacy of a minimal home-based psychoeducative intervention in patients with advanced COPD: A randomised controlled trial

    DEFF Research Database (Denmark)

    Gaby Bové, Dorthe; Lomborg, Kirsten; Jensen, A.K.

    2016-01-01

    BACKGROUND: Anxiety is a common comorbidity in patients with advanced Chronic Obstructive Pulmonary Disease (COPD) with major impact on quality of life and associated with increased risk of death. The objective of this randomised controlled trial was to test the efficacy of a minimal home......-based psychoeducative intervention versus usual care for reducing symptoms of anxiety in patients with advanced COPD. METHODS: The trial included 66 participants with advanced COPD and symptoms of anxiety. The primary outcome was anxiety assessed by the Hospital Anxiety and Depression scale (HADS) subscale for anxiety......, compared with the control group (p = 0.005), indicating a significant effect of the intervention. The average difference between the groups in HADS-A was 2.16 points (CI = [0.62; 3.71]) at one month and 2.32 points (CI = [0.74; 3.89]) at three months follow-up. The intervention group had a higher post...

  18. Recent advance in nonlinear aeroelastic analysis and control of the aircraft

    Directory of Open Access Journals (Sweden)

    Xiang Jinwu

    2014-02-01

    Full Text Available A review on the recent advance in nonlinear aeroelasticity of the aircraft is presented in this paper. The nonlinear aeroelastic problems are divided into three types based on different research objects, namely the two dimensional airfoil, the wing, and the full aircraft. Different nonlinearities encountered in aeroelastic systems are discussed firstly, where the emphases is placed on new nonlinear model to describe tested nonlinear relationship. Research techniques, especially new theoretical methods and aeroelastic flutter control methods are investigated in detail. The route to chaos and the cause of chaotic motion of two-dimensional aeroelastic system are summarized. Various structural modeling methods for the high-aspect-ratio wing with geometric nonlinearity are discussed. Accordingly, aerodynamic modeling approaches have been developed for the aeroelastic modeling of nonlinear high-aspect-ratio wings. Nonlinear aeroelasticity about high-altitude long-endurance (HALE and fight aircrafts are studied separately. Finally, conclusions and the challenges of the development in nonlinear aeroelasticity are concluded. Nonlinear aeroelastic problems of morphing wing, energy harvesting, and flapping aircrafts are proposed as new directions in the future.

  19. Recent advance in nonlinear aeroelastic analysis and control of the aircraft

    Institute of Scientific and Technical Information of China (English)

    Xiang Jinwu; Yan Yongju; Li Daochun

    2014-01-01

    A review on the recent advance in nonlinear aeroelasticity of the aircraft is presented in this paper. The nonlinear aeroelastic problems are divided into three types based on different research objects, namely the two dimensional airfoil, the wing, and the full aircraft. Different non-linearities encountered in aeroelastic systems are discussed firstly, where the emphases is placed on new nonlinear model to describe tested nonlinear relationship. Research techniques, especially new theoretical methods and aeroelastic flutter control methods are investigated in detail. The route to chaos and the cause of chaotic motion of two-dimensional aeroelastic system are summarized. Var-ious structural modeling methods for the high-aspect-ratio wing with geometric nonlinearity are dis-cussed. Accordingly, aerodynamic modeling approaches have been developed for the aeroelastic modeling of nonlinear high-aspect-ratio wings. Nonlinear aeroelasticity about high-altitude long-endurance (HALE) and fight aircrafts are studied separately. Finally, conclusions and the chal-lenges of the development in nonlinear aeroelasticity are concluded. Nonlinear aeroelastic problems of morphing wing, energy harvesting, and flapping aircrafts are proposed as new directions in the future.

  20. Point-of-care testing for sexually transmitted infections: recent advances and implications for disease control

    Science.gov (United States)

    Tucker, Joseph D.; Bien, Cedric H.; Peeling, Rosanna W.

    2013-01-01

    Purpose of review Sexually transmitted infections (STIs) remain a major global public health issue, with more than 448 million incident bacterial infections each year. We review recent advances in STI point-of-care (POC) testing and implications for STI prevention and control. Recent findings Accurate immunochromatographic assays to detect HIV, hepatitis C virus (HCV) and syphilis antibodies have made home or supervised self-testing possible. Several studies have demonstrated feasibility and excellent test characteristics for HIV, HCV and syphilis POC tests. Rapid oral HIV tests are now available for purchase at retail sites across the United States. Combined HIV and syphilis tests using a single finger prick blood sample are under evaluation. Summary Oral POC STI tests with comparable performance to blood-based POC tests are available for self-testing. POC tests can expand screening, improve syndromic management and reduce loss to follow up. POC STI tests have the potential to facilitate prompt treatment and partner services. POC STI tests create opportunities for new social and financial models of community-based testing services. Increasing equity and access to testing will create challenges in linkage to care, quality assurance, partner services and surveillance. These important developments warrant research to understand appropriate contexts for implementation. PMID:23242343

  1. Site-controlled and advanced epitaxial Ge/Si quantum dots: fabrication, properties, and applications

    Science.gov (United States)

    Brehm, Moritz; Grydlik, Martyna

    2017-09-01

    In this review, we report on fabrication paths, challenges, and emerging solutions to integrate group-IV epitaxial quantum dots (QDs) as active light emitters into the existing standard Si technology. Their potential as laser gain material for the use of optical intra- and inter-chip interconnects as well as possibilities to combine a single-photon-source-based quantum cryptographic means with Si technology will be discussed. We propose that the mandatory addressability of the light emitters can be achieved by a combination of organized QD growth assisted by templated self-assembly, and advanced inter-QD defect engineering to boost the optical emissivity of group-IV QDs at room-temperature. Those two main parts, the site-controlled growth and the light emission enhancement in QDs through the introduction of single defects build the main body of the review. This leads us to a roadmap for the necessary further development of this emerging field of CMOS-compatible group-IV QD light emitters for on-chip applications.

  2. Bovine viral diarrhea virus infections: manifestations of infection and recent advances in understanding pathogenesis and control.

    Science.gov (United States)

    Brodersen, B W

    2014-03-01

    Bovine viral diarrhea virus (BVDV) continues to be of economic significance to the livestock industry in terms of acute disease and fetal loss. Many of the lesions relating to BVDV infection have been well described previously. The virus is perpetuated in herds through the presence of calves that are persistently infected. Relationships between various species and biotypes of BVDV and host defenses are increasingly understood. Understanding of the host defense mechanisms of innate immunity and adaptive immunity continues to improve, and the effects of the virus on these immune mechanisms are being used to explain how persistent infection develops. The noncytopathic biotype of BVDV plays the major role in its effects on the host defenses by inhibiting various aspects of the innate immune system and creation of immunotolerance in the fetus during early gestation. Recent advances have allowed for development of affordable test strategies to identify and remove persistently infected animals. With these improved tests and removal strategies, the livestock industry can begin more widespread effective control programs.

  3. Recent advances in understanding the biology, epidemiology and control of chlamydial infections in koalas.

    Science.gov (United States)

    Polkinghorne, Adam; Hanger, Jon; Timms, Peter

    2013-08-30

    The koala (Phascolarctos cinereus) is recognised as a threatened wildlife species in various parts of Australia. A major contributing factor to the decline and long-term viability of affected populations is disease caused by the obligate intracellular bacteria, Chlamydia. Two chlamydial species infect the koala, Chlamydia pecorum and Chlamydia pneumoniae, and have been reported in nearly all mainland koala populations. Chlamydial infections of koalas are associated with ocular infections leading to blindness and genital tract infections linked to infertility, among other serious clinical manifestations. Diagnosis can be based on clinical presentation alone, however, it is complicated by the observation that many koala chlamydial infections occur with no overt signs of clinical disease. Instead, accurate diagnosis requires detailed clinical assessment and confirmatory testing by a range of PCR-based assays. Antibiotic treatment for koala chlamydial infection is possible, however, results on its success are mixed. A more practical solution for the protection of diseased populations is the application of a koala Chlamydia vaccine, with recent trials indicating promising results. Interestingly, molecular epidemiology studies of koala C. pecorum infections and recent comparative genomic analyses of koala C. pneumoniae have revealed potential differences in their origin that will have wider ramifications for our understanding of human chlamydial infections and host adaptation of the chlamydiae. This review summarises changes to the taxonomy of koala chlamydial infections and recent advances in our understanding of the epidemiology, diagnosis, treatment, control and evolution of Chlamydia infections in this iconic wildlife species. Copyright © 2013 Elsevier B.V. All rights reserved.

  4. Detecting method of subjects' 3D positions and experimental advanced camera control system

    Science.gov (United States)

    Kato, Daiichiro; Abe, Kazuo; Ishikawa, Akio; Yamada, Mitsuho; Suzuki, Takahito; Kuwashima, Shigesumi

    1997-04-01

    Steady progress is being made in the development of an intelligent robot camera capable of automatically shooting pictures with a powerful sense of reality or tracking objects whose shooting requires advanced techniques. Currently, only experienced broadcasting cameramen can provide these pictures.TO develop an intelligent robot camera with these abilities, we need to clearly understand how a broadcasting cameraman assesses his shooting situation and how his camera is moved during shooting. We use a real- time analyzer to study a cameraman's work and his gaze movements at studios and during sports broadcasts. This time, we have developed a detecting method of subjects' 3D positions and an experimental camera control system to help us further understand the movements required for an intelligent robot camera. The features are as follows: (1) Two sensor cameras shoot a moving subject and detect colors, producing its 3D coordinates. (2) Capable of driving a camera based on camera movement data obtained by a real-time analyzer. 'Moving shoot' is the name we have given to the object position detection technology on which this system is based. We used it in a soccer game, producing computer graphics showing how players moved. These results will also be reported.

  5. CONTROL OF MHD STABILITY IN DIII-D ADVANCED TOKAMAK DISCHARGES

    Energy Technology Data Exchange (ETDEWEB)

    STRAIT,EJ; BIALEK,J; CHANCE,MS; CHU,MS; EDGELL,DH; FERRON,JR; GREENFIELD,CM; GAROFALO,AM; HUMPHREYS,DA; JACKSON,GL; JAYAKUMAR,RJ; JERNIGAN,TC; KIM,JS; LA HAYE,RJ; LAO,LL; LUCE,TC; MAKOWSKI,MA; MURAKAMI,M; NAVRATIL,GA; OKABAYASHI,M; PETTY,CC; REIMERDES,H; SCOVILLE,JT; TURNBULL,AD; WADE,MR; WALKER,ML; WHYTE,DG; DIII-D TEAM

    2003-06-01

    OAK-B135 Advanced tokamak research in DIII-D seeks to optimize the tokamak approach for fusion energy production, leading to a compact, steady state power source. High power density implies operation at high toroidal beta, {beta}{sub T}=

    2{micro}{sub 0}/B{sub T}{sup 2}, since fusion power density increases roughly as the square of the plasma pressure. Steady-state operation with low recirculating power for current drive implies operation at high poloidal beta, {beta}{sub P} =

    2{micro}{sub 0}/{sup 2}, in order to maximize the fraction of self-generated bootstrap current. Together, these lead to a requirement of operation at high normalized beta, {beta}{sub N} = {beta}{sub T}(aB/I), since {beta}{sub P}{beta}{sub T} {approx} 25[(1+{kappa}{sup 2})/2] ({beta}{sub N}/100){sup 2}. Plasmas with high normalized beta are likely to operate near one or more stability limits, so control of MHD stability in such plasmas is crucial.

  6. Facility level thermal systems for the Advanced Technology Solar Telescope

    Science.gov (United States)

    Phelps, LeEllen; Murga, Gaizka; Fraser, Mark; Climent, Tània

    2012-09-01

    The management and control of the local aero-thermal environment is critical for success of the Advanced Technology Solar Telescope (ATST). In addition to minimizing disturbances to local seeing, the facility thermal systems must meet stringent energy efficiency requirements to minimize impact on the surrounding environment and meet federal requirements along with operational budgetary constraints. This paper describes the major facility thermal equipment and systems to be implemented along with associated energy management features. The systems presented include the central plant, the climate control systems for the computer room and coudé laboratory, the carousel cooling system which actively controls the surface temperature of the rotating telescope enclosure, and the systems used for active and passive ventilation of the telescope chamber.

  7. 细菌应激反应中(p)ppGpp代谢的调控%Modulation of (p)ppGpp metabolism during bacterial stringent response

    Institute of Scientific and Technical Information of China (English)

    刘彪; 宁德刚

    2011-01-01

    (p)ppGpp is a well known intracellular signal that mediates bacterial stringent response to environment stresses through the change of its concentration level thus controls many important cellular processes for bacterial survival. In this review, we outline the mechanism of (p)ppGpp action, the enzyme system involved in (p)ppGpp metabolism, and summarize the signal transmission, the regulation and the diversity of (p)ppGpp metabolism. Moreover, we give a brief introduction on our achieved results recently about (p)ppGpp metabolism in cyanobacteria, and predict that a (p)ppGpp new metabolic mechanism different from those known exists in cyanobacteria.%(p)ppGpp是介导细菌细胞对环境胁迫产生应激反应的重要胞内信号,通过控制一系列重要的细胞活动使细菌得以生存.通过对蓝细菌中(p)ppGpp代谢的研究,对(p)ppGpp作用机制、控制(p)ppGpp代谢的酶系统、环境胁迫信号传递、细胞中(p)ppGpp水平的调控及其多样性进行了总结.

  8. A comparison of dicarbonyl stress and advanced glycation endproducts in lifelong endurance athletes vs. sedentary controls.

    Science.gov (United States)

    Maessen, Martijn F H; Schalkwijk, Casper G; Verheggen, Rebecca J H M; Aengevaeren, Vincent L; Hopman, Maria T E; Eijsvogels, Thijs M H

    2017-10-01

    Dicarbonyl stress and high concentrations of advanced glycation endproducts (AGEs) relate to an elevated risk for cardiovascular diseases (CVD). Exercise training lowers the risk for future CVD. We tested the hypothesis that lifelong endurance athletes have lower dicarbonyl stress and AGEs compared to sedentary controls and that these differences relate to a better cardiovascular health profile. Cross-sectional study. We included 18 lifelong endurance athletes (ATH, 61±7years) and 18 sedentary controls (SED, 58±7years) and measured circulating glyoxal (GO), methylglyoxal (MGO) and 3-deoxyglucosone (3DG) as markers of dicarbonyl stress. Furthermore, we measured serum levels of protein-bound AGEs N(Ɛ)-(carboxymethyl)lysine (CML), N(Ɛ)-(carboxyethyl)lysine (CEL), methylglyoxal-derived hydroimidazolone-1 (MG-H1), and pentosidine. Additionally, we measured cardiorespiratory fitness (VO2peak) and cardiovascular health markers. ATH had lower concentrations of MGO (196 [180-246] vs. 242 [207-292] nmol/mmol lysine, p=0.043) and 3DG (927 [868-972] vs. 1061 [982-1114] nmol/mmol lysine, pcorrelated with cardiovascular health markers, whereas CML and CEL were positively correlated with VO2peak and cardiovascular health markers. Lifelong exercise training relates to lower dicarbonyl stress (MGO and 3DG) and the AGE MG-H1. The underlying mechanism and (clinical) relevance of higher CML and CEL concentrations among lifelong athletes warrants future research, since it conflicts with the idea that higher AGE concentrations relate to poor cardiovascular health outcomes. Copyright © 2017 Sports Medicine Australia. Published by Elsevier Ltd. All rights reserved.

  9. Advanced use of high-performance liquid chromatography for synthesis of controlled metal clusters.

    Science.gov (United States)

    Niihori, Yoshiki; Matsuzaki, Miku; Uchida, Chihiro; Negishi, Yuichi

    2014-07-21

    Because the synthesis of metal clusters with multiple ligand types results in a distribution of ligands, high-resolution separation of each unique cluster from the mixture is required for precise control of the ligand composition. Reverse-phase high-performance liquid chromatography combined with appropriate transitioning of the mobile phase composition is an extremely effective means of separating ligand combinations when working with metal clusters protected by two different types of thiolates. We report herein advanced use of this method. The studies involving Au₂₄Pd(SR₁)₁₈-x(SR₂)x and Au₂₄Pd(SR₁)₁₈-x(SeR₂)x (SR₁, SR₂ = thiolate, SeR₂ = selenolate) revealed the following. (1) In general, an increase in the difference between the polarities of the functional groups incorporated in the two types of ligands improves the separation resolution. A suitable ligand combination for separation can be predicted from the retention times of Au₂₄Pd(SR₁)₁₈ and Au₂₄Pd(SR₂)₁₈, which cause the terminal peaks in a series of peaks. (2) The use of a step-gradient program during the mobile phase substitution results in improved resolution compared to that achievable with the linear gradients applied in prior work. (3) This technique is also useful for the evaluation of the chemical compositions of metal clusters protected by two different types of ligands with similar molecular weights. These findings will provide clear design guidelines for the functionalization of metal clusters via control of the ligand composition, and will also improve our understanding of the high-resolution isolation of metal clusters.

  10. PREVENTING LITHOGRAPHY-INDUCED MAVERICK YIELD EVENTS WITH A DISPENSE SYSTEM ADVANCED EQUIPMENT CONTROL METHOD

    Institute of Scientific and Technical Information of China (English)

    Jennifer Broggin

    2012-01-01

    As semiconductor manufacturers march to thedrum beat of Moore's Law there is very little roomfor yield maverieks, especially those that can beprevented. Critical process errors are costly andphotolithography is one of the few processes insemiconductor manufacturing where there is anopportunity to correct errors. Small changes inphotoresist-dispensed volume may have severeimpact on film thickness uniformity and can ulti-mately affect patterning It is important to monitorphoto dispense conditions to detect real-timeevents that may have a direct negative impact onprocess yield and be able to react to these eventsas quickly as possible.This paper presents an evaluation of the IntelliGen Mini, a photoresist dispense system manufacturedby Entegris, Inc. This system utilizes advancedequipment control software, known as dispenseconfirmation, to detect variations in photo dis-pense. These variations, caused by bubbles inthe dispense line, valve errors and accidentally-changed chemistries can all create maverick yieldevents that can go undetected until metrology,defeet inspection or wafer final testThe ability of an advanced dispense system todetect events and create alerts is a very powerfultool, but it can be most effective when that infor-mation is collected and analyzed by an automatedsystem. In a modern fabricator this is most likely astatistical process control chart that is monitoringa track's progress and is ready to stop the trackwhen a maverick event occurs or alert personnelto trends they may not otherwise catch with otherinline ntetrology data. Dispense confirmation,when Combined with networking capabilities,can meet this need.After a brief description of the pump, data from sim-ulated yield-affecting events will be examined toevaluate the IntelliGen Mini's ability to detect them.This discussion will eonclude with a brief analysisof the ultilnate time and cost savings of utilizingdispense confirmation with networking capabilitiesto detect and eliminate poorly

  11. Fieldcrest Cannon, Inc. Advanced Technical Preparation. Statistical Process Control (SPC). PRE-SPC 11: SPC & Graphs. Instructor Book.

    Science.gov (United States)

    Averitt, Sallie D.

    This instructor guide, which was developed for use in a manufacturing firm's advanced technical preparation program, contains the materials required to present a learning module that is designed to prepare trainees for the program's statistical process control module by improving their basic math skills in working with line graphs and teaching…

  12. Energy Savings and Economics of Advanced Control Strategies for Packaged Air-Conditioning Units with Gas Heat

    Energy Technology Data Exchange (ETDEWEB)

    Wang, Weimin; Katipamula, Srinivas; Huang, Yunzhi; Brambley, Michael R.

    2011-12-31

    Pacific Northwest National Laboratory (PNNL) with funding from the U.S. Department of Energy's Building Technologies Program (BTP) evaluated a number of control strategies that can be implemented in a controller, to improve the operational efficiency of the packaged air conditioning units. The two primary objectives of this research project are: (1) determine the magnitude of energy savings achievable by retrofitting existing packaged air conditioning units with advanced control strategies not ordinarily used for packaged units and (2) estimating what the installed cost of a replacement control with the desired features should be in various regions of the U.S. This document reports results of the study.

  13. Advances in Statistical Control, Algebraic Systems Theory, and Dynamic Systems Characteristics A Tribute to Michael K Sain

    CERN Document Server

    Won, Chang-Hee; Michel, Anthony N

    2008-01-01

    This volume - dedicated to Michael K. Sain on the occasion of his seventieth birthday - is a collection of chapters covering recent advances in stochastic optimal control theory and algebraic systems theory. Written by experts in their respective fields, the chapters are thematically organized into four parts: Part I focuses on statistical control theory, where the cost function is viewed as a random variable and performance is shaped through cost cumulants. In this respect, statistical control generalizes linear-quadratic-Gaussian and H-infinity control. Part II addresses algebraic systems th

  14. 9 CFR 318.24 - Product prepared using advanced meat/bone separation machinery; process control.

    Science.gov (United States)

    2010-01-01

    ... 9 Animals and Animal Products 2 2010-01-01 2010-01-01 false Product prepared using advanced meat... MEAT AND POULTRY PRODUCTS INSPECTION AND VOLUNTARY INSPECTION AND CERTIFICATION ENTRY INTO OFFICIAL ESTABLISHMENTS; REINSPECTION AND PREPARATION OF PRODUCTS General § 318.24 Product prepared using advanced meat...

  15. Advanced Power Electronic Interfaces for Distributed Energy Systems, Part 2: Modeling, Development, and Experimental Evaluation of Advanced Control Functions for Single-Phase Utility-Connected Inverter

    Energy Technology Data Exchange (ETDEWEB)

    Chakraborty, S.; Kroposki, B.; Kramer, W.

    2008-11-01

    Integrating renewable energy and distributed generations into the Smart Grid architecture requires power electronic (PE) for energy conversion. The key to reaching successful Smart Grid implementation is to develop interoperable, intelligent, and advanced PE technology that improves and accelerates the use of distributed energy resource systems. This report describes the simulation, design, and testing of a single-phase DC-to-AC inverter developed to operate in both islanded and utility-connected mode. It provides results on both the simulations and the experiments conducted, demonstrating the ability of the inverter to provide advanced control functions such as power flow and VAR/voltage regulation. This report also analyzes two different techniques used for digital signal processor (DSP) code generation. Initially, the DSP code was written in C programming language using Texas Instrument's Code Composer Studio. In a later stage of the research, the Simulink DSP toolbox was used to self-generate code for the DSP. The successful tests using Simulink self-generated DSP codes show promise for fast prototyping of PE controls.

  16. Advanced In-Furnace NOx Control for Wall and Cyclone-Fired Boilers

    Energy Technology Data Exchange (ETDEWEB)

    Hamid Sarv

    2009-02-28

    A NO{sub x} minimization strategy for coal-burning wall-fired and cyclone boilers was developed that included deep air staging, innovative oxygen use, reburning, and advanced combustion control enhancements. Computational fluid dynamics modeling was applied to refine and select the best arrangements. Pilot-scale tests were conducted by firing an eastern high-volatile bituminous Pittsburgh No.8 coal at 5 million Btu/hr in a facility that was set up with two-level overfire air (OFA) ports. In the wall-fired mode, pulverized coal was burned in a geometrically scaled down version of the B and W DRB-4Z{reg_sign} low-NO{sub x} burner. At a fixed overall excess air level of 17%, NO{sub x} emissions with single-level OFA ports were around 0.32 lb/million Btu at 0.80 burner stoichiometry. Two-level OFA operation lowered the NO{sub x} levels to 0.25 lb/million Btu. Oxygen enrichment in the staged burner reduced the NO{sub x} values to 0.21 lb/million Btu. Oxygen enrichment plus reburning and 2-level OFA operation further curbed the NO{sub x} emissions to 0.19 lb/million Btu or by 41% from conventional air-staged operation with single-level OFA ports. In the cyclone firing arrangement, oxygen enrichment of the cyclone combustor enabled high-temperature and deeply staged operation while maintaining good slag tapping. Firing the Pittsburgh No.8 coal in the optimum arrangement generated 112 ppmv NO{sub x} (0.15 lb/million Btu) and 59 ppmv CO. The optimum emissions results represent 88% NO{sub x} reduction from the uncontrolled operation. Levelized costs for additional NO{sub x} removal by various in-furnace control methods in reference wall-fired or cyclone-fired units already equipped with single-level OFA ports were estimated and compared with figures for SCR systems achieving 0.1 lb NO{sub x}/10{sup 6} Btu. Two-level OFA ports could offer the most economical approach for moderate NO{sub x} control, especially for smaller units. O{sub 2} enrichment in combination with 2-level

  17. Proceedings of the Twenty-First Water Reactor Safety Information Meeting: Volume 1, Plenary session; Advanced reactor research; advanced control system technology; advanced instrumentation and control hardware; human factors research; probabilistic risk assessment topics; thermal hydraulics; thermal hydraulic research for advanced passive LWRs

    Energy Technology Data Exchange (ETDEWEB)

    Monteleone, S. [Brookhaven National Lab., Upton, NY (United States)] [comp.

    1994-04-01

    This three-volume report contains 90 papers out of the 102 that were presented at the Twenty-First Water Reactor Safety Information Meeting held at the Bethesda Marriott Hotel, Bethesda, Maryland, during the week of October 25--27, 1993. The papers are printed in the order of their presentation in each session and describe progress and results of programs in nuclear safety research conducted in this country and abroad. Foreign participation in the meeting included papers presented by researchers from France, Germany, Japan, Russia, Switzerland, Taiwan, and United Kingdom. The titles of the papers and the names of the authors have been updated and may differ from those that appeared in the final program of the meeting. Individual papers have been cataloged separately. This document, Volume 1 covers the following topics: Advanced Reactor Research; Advanced Instrumentation and Control Hardware; Advanced Control System Technology; Human Factors Research; Probabilistic Risk Assessment Topics; Thermal Hydraulics; and Thermal Hydraulic Research for Advanced Passive Light Water Reactors.

  18. Advanced Communication and Control for Distributed Energy Resource Integration: Phase 2 Scientific Report

    Energy Technology Data Exchange (ETDEWEB)

    BPL Global

    2008-09-30

    The objective of this research project is to demonstrate sensing, communication, information and control technologies to achieve a seamless integration of multivendor distributed energy resource (DER) units at aggregation levels that meet individual user requirements for facility operations (residential, commercial, industrial, manufacturing, etc.) and further serve as resource options for electric and natural gas utilities. The fully demonstrated DER aggregation system with embodiment of communication and control technologies will lead to real-time, interactive, customer-managed service networks to achieve greater customer value. Work on this Advanced Communication and Control Project (ACCP) consists of a two-phase approach for an integrated demonstration of communication and control technologies to achieve a seamless integration of DER units to reach progressive levels of aggregated power output. Phase I involved design and proof-of-design, and Phase II involves real-world demonstration of the Phase I design architecture. The scope of work for Phase II of this ACCP involves demonstrating the Phase I design architecture in large scale real-world settings while integrating with the operations of one or more electricity supplier feeder lines. The communication and control architectures for integrated demonstration shall encompass combinations of software and hardware components, including: sensors, data acquisition and communication systems, remote monitoring systems, metering (interval revenue, real-time), local and wide area networks, Web-based systems, smart controls, energy management/information systems with control and automation of building energy loads, and demand-response management with integration of real-time market pricing. For Phase II, BPL Global shall demonstrate the Phase I design for integrating and controlling the operation of more than 10 DER units, dispersed at various locations in one or more Independent System Operator (ISO) Control Areas, at

  19. Cancer Pain Control for Advanced Cancer Patients by Using Autonomic Nerve Pharmacopuncture

    Directory of Open Access Journals (Sweden)

    Hwi-joong Kang

    2014-09-01

    Full Text Available Objectives: The purpose of this study is to report a case series of advanced cancer patients whose cancer pain was relieved by using autonomic nerve pharmacopuncture (ANP treatment. ANP is a subcutaneous injection therapy of mountain ginseng pharmacopuncture (MGP along the acupoints on the spine (Hua-Tuo-Jia-Ji-Xue; 0.5 cun lateral to the lower border of the spinous processes of vertebrae to enhance the immune system and to balance autonomic nerve function. Methods: Patients with three different types of cancer (gastric cancer, lung cancer, colon cancer with distant metastases with cancer pain were treated with ANP. 1 mL of MGP was injected into the bilateral Hua-Tuo-Jia-Ji-Xue on the T1-L5 sites (total 12 ─ 20 mL injection of each patient’s dorsum by using the principle of symptom differentiation. During ANP treatment, the visual analogue scale (VAS for pain was used to assess their levels of cancer pain; also, the dosage and the frequency of analgesic use were measured. Results: The cancer pain levels of all three patients improved with treatment using ANP. The VAS scores of the three patients decreased as the treatment progressed. The dosage and the frequency of analgesics also gradually decreased during the treatment period. Significantly, no related adverse events were found. Conclusion: ANP has shown benefit in controlling cancer pain for the three different types of cancer investigated in this study and in reducing the dosage and the frequency of analgesics. ANP is expected to be beneficial for reducing cancer pain and, thus, to be a promising new treatment for cancer pain.

  20. Advances in surveillance of periodontitis: the Centers for Disease Control and Prevention periodontal disease surveillance project.

    Science.gov (United States)

    Eke, Paul I; Thornton-Evans, Gina; Dye, Bruce; Genco, Robert

    2012-11-01

    The Centers for Disease Control and Prevention (CDC) has as one of its strategic goals to support and improve surveillance of periodontal disease. In 2003, the CDC initiated the CDC Periodontal Disease Surveillance Project in collaboration with the American Academy of Periodontology to address population-based surveillance of periodontal disease at the local, state, and national levels. This initiative has made significant advancements toward the goal of improved surveillance, including developing valid self-reported measures that can be obtained from interview-based surveys to predict prevalence of periodontitis in populations. This will allow surveillance of periodontitis at the state and local levels and in countries where clinical resources for surveillance are scarce. This work has produced standard case definitions for surveillance of periodontitis that are now widely recognized and applied in population studies and research. At the national level, this initiative has evaluated the validity of previous clinical examination protocols and tested new protocols on the National Health and Nutrition Examination Survey (NHANES), recommending and supporting funding for the gold-standard full-mouth periodontal examination in NHANES 2009 to 2012. These examinations will generate accurate estimates of the prevalence of periodontitis in the US adult population and provide a superior dataset for surveillance and research. Also, this data will be used to generate the necessary coefficients for our self-report questions for use in subsets of the total US population. The impact of these findings on population-based surveillance of periodontitis and future directions of the project are discussed along with plans for dissemination and translation efforts for broader public health use.

  1. Recent advances in automotive catalysis for NOx emission control by small-pore microporous materials.

    Science.gov (United States)

    Beale, A M; Gao, F; Lezcano-Gonzalez, I; Peden, C H F; Szanyi, J

    2015-10-21

    The ever increasing demand to develop highly fuel efficient engines coincides with the need to minimize air pollution originating from the exhaust gases of internal combustion engines. Dramatically improved fuel efficiency can be achieved at air-to-fuel ratios much higher than stoichiometric. In the presence of oxygen in large excess, however, traditional three-way catalysts are unable to reduce NOx. Among the number of lean-NOx reduction technologies, selective catalytic reduction (SCR) of NOx by NH3 over Cu- and Fe-ion exchanged zeolite catalysts has been extensively studied over the past 30+ years. Despite the significant advances in developing a viable practical zeolite-based catalyst for lean NOx reduction, the insufficient hydrothermal stabilities of the zeolite structures considered cast doubts about their real-world applicability. During the past decade renewed interest in zeolite-based lean NOx reduction was spurred by the discovery of the very high activity of Cu-SSZ-13 (and the isostructural Cu-SAPO-34) in the NH3-SCR of NOx. These new, small-pore zeolite-based catalysts not only exhibited very high NOx conversion and N2 selectivity, but also exhibited exceptionally high hydrothermal stability at high temperatures. In this review we summarize the key discoveries of the past ∼5 years that led to the introduction of these catalysts into practical applications. This review first briefly discusses the structure and preparation of the CHA structure-based zeolite catalysts, and then summarizes the key learnings of the rather extensive (but not complete) characterisation work. Then we summarize the key findings of reaction kinetic studies, and provide some mechanistic details emerging from these investigations. At the end of the review we highlight some of the issues that still need to be addressed in automotive exhaust control catalysis.

  2. Advanced Supported Liquid Membranes for Carbon Dioxide Control in Cabin Applications

    Science.gov (United States)

    Wickham, David T.; Gleason, Kevin J.; Engel, Jeffrey R.; Chullen, Cinda

    2016-01-01

    The development of new, robust, life support systems is critical to NASA's continued progress in space exploration. One vital function is maintaining the carbon dioxide (CO2) concentration in the cabin at levels that do not impair the health or performance of the crew. The CO2 removal assembly (CDRA) is the current CO2 control technology on-board the International Space Station (ISS). Although the CDRA has met the needs of the ISS to date, the repeated cycling of the molecular sieve sorbent causes it to break down into small particles that clog filters or generate dust in the cabin. This reduces reliability and increases maintenance requirements. Another approach that has potential advantages over the current system is a membrane that separates CO2 from air. In this approach, cabin air contacts one side of the membrane while other side of the membrane is maintained at low pressure to create a driving force for CO2 transport across the membrane. In this application, the primary power requirement is for the pump that creates the low pressure and then pumps the CO2 to the oxygen recovery system. For such a membrane to be practical, it must have high CO2 permeation rate and excellent selectivity for CO2 over air. Unfortunately, conventional gas separation membranes do not have adequate CO2 permeability and selectivity to meet the needs of this application. However, the required performance could be obtained with a supported liquid membrane (SLM), which consists of a microporous material filled with a liquid that selectively reacts with CO2 over air. In a recently completed Phase II SBIR project, Reaction Systems, Inc. fabricated an SLM that is very close to meeting permeability and selectivity objectives for use in the advanced space suit portable life support system. This paper describes work carried out to evaluate its potential for use in spacecraft cabin application.

  3. Advanced Modeling of Cold Crucible Induction Melting for Process Control and Optimization

    Energy Technology Data Exchange (ETDEWEB)

    J. A. Roach; D. B. Lopukh; A. P. Martynov; B. S. Polevodov; S. I. Chepluk

    2008-02-01

    The Idaho National Laboratory (INL) and the St. Petersburg Electrotechnical University “LETI” (ETU) have collaborated on development and validation of an advanced numerical model of the cold crucible induction melting (CCIM) process. This work was conducted in support of the Department of Energy (DOE) Office of Environmental Management Technology and Engineering (EM-20) International Program. The model predicts quasi-steady state temperature distributions, convection cell configurations, and flow field velocities for a fully established melt of low conductivity non-magnetic materials at high frequency operations. The INL/ETU ANSYS© finite element model is unique in that it has been developed specifically for processing borosilicate glass (BSG) and other glass melts. Specifically, it accounts for the temperature dependency of key material properties, some of which change by orders of magnitude within the temperature ranges experienced (temperature differences of 500oC are common) in CCIM processing of glass, including density, viscosity, thermal conductivity, specific heat, and electrical resistivity. These values, and their responses to temperature changes, are keys to understanding the melt characteristics. Because the model has been validated, it provides the capability to conduct parametric studies to understand operational sensitivities and geometry effects. Additionally, the model can be used to indirectly determine difficult to measure material properties at higher temperatures such as resistivity, thermal conductivity and emissivity. The model can also be used to optimize system design and to predict operational behavior for specific materials and system configurations, allowing automated feedback control. This becomes particularly important when designing melter systems for full-scale industrial applications.

  4. Promoting advance planning for health care and research among older adults: A randomized controlled trial

    Directory of Open Access Journals (Sweden)

    Bravo Gina

    2012-01-01

    Full Text Available Abstract Background Family members are often required to act as substitute decision-makers when health care or research participation decisions must be made for an incapacitated relative. Yet most families are unable to accurately predict older adult preferences regarding future health care and willingness to engage in research studies. Discussion and documentation of preferences could improve proxies' abilities to decide for their loved ones. This trial assesses the efficacy of an advance planning intervention in improving the accuracy of substitute decision-making and increasing the frequency of documented preferences for health care and research. It also investigates the financial impact on the healthcare system of improving substitute decision-making. Methods/Design Dyads (n = 240 comprising an older adult and his/her self-selected proxy are randomly allocated to the experimental or control group, after stratification for type of designated proxy and self-report of prior documentation of healthcare preferences. At baseline, clinical and research vignettes are used to elicit older adult preferences and assess the ability of their proxy to predict those preferences. Responses are elicited under four health states, ranging from the subject's current health state to severe dementia. For each state, we estimated the public costs of the healthcare services that would typically be provided to a patient under these scenarios. Experimental dyads are visited at home, twice, by a specially trained facilitator who communicates the dyad-specific results of the concordance assessment, helps older adults convey their wishes to their proxies, and offers assistance in completing a guide entitled My Preferences that we designed specifically for that purpose. In between these meetings, experimental dyads attend a group information session about My Preferences. Control dyads attend three monthly workshops aimed at promoting healthy behaviors. Concordance

  5. The process of advance care planning in HCT candidates and proxies: self-efficacy, locus of control, and anxiety levels.

    Science.gov (United States)

    Duckworth, Katharine E; Forti, Allison M; Russell, Gregory B; Naik, Seema; Hurd, David; McQuellon, Richard P

    2014-11-01

    The purpose of this study was to examine the relationship between hematopoietic cell transplant candidate and proxy advance care planning (ACP) behavior and attitudes. A total of 49 candidates and 44 proxies completed the Advance Directive Attitudes Survey, Multidimensional Health Locus of Control Scale, Family Decision Making Self-Efficacy Scale, and the State-Trait Anxiety Inventory. In all, 45% of candidates reported completing an advance directive (AD), while only 26% had ADs on file; 80% of candidates discussed ACP wishes with their loved ones and 15% discussed ACP wishes with their medical team. The AD completers were significantly (1) older, (2) more positive about ADs, and (3) were less likely to believe that health events happen by chance. Discrepancies between reported ACP behavior and communication with health care practitioners have implications for end-of-life care. © The Author(s) 2013.

  6. What Is the Link between Stringent Response, Endoribonuclease Encoding Type II Toxin-Antitoxin Systems and Persistence?

    Science.gov (United States)

    Ramisetty, Bhaskar C M; Ghosh, Dimpy; Roy Chowdhury, Maoumita; Santhosh, Ramachandran S

    2016-01-01

    Persistence is a transient and non-inheritable tolerance to antibiotics by a small fraction of a bacterial population. One of the proposed determinants of bacterial persistence is toxin-antitoxin systems (TASs) which are also implicated in a wide range of stress-related phenomena. Maisonneuve E, Castro-Camargo M, Gerdes K. 2013. Cell 154:1140-1150 reported an interesting link between ppGpp mediated stringent response, TAS, and persistence. It is proposed that accumulation of ppGpp enhances the accumulation of inorganic polyphosphate which modulates Lon protease to degrade antitoxins. The decrease in the concentration of antitoxins supposedly activated the toxin to increase in the number of persisters during antibiotic treatment. In this study, we show that inorganic polyphosphate is not required for transcriptional activation of yefM/yoeB TAS, which is an indirect indication of Lon-dependent degradation of YefM antitoxin. The Δ10 strain, an Escherichia coli MG1655 derivative in which the 10 TAS are deleted, is more sensitive to ciprofloxacin compared to wild type MG1655. Furthermore, we show that the Δ10 strain has relatively lower fitness compared to the wild type and hence, we argue that the persistence related implications based on Δ10 strain are void. We conclude that the transcriptional regulation and endoribonuclease activity of YefM/YoeB TAS is independent of ppGpp and inorganic polyphosphate. Therefore, we urge for thorough inspection and debate on the link between chromosomal endoribonuclease TAS and persistence.

  7. Warm Jupiters Need Close "Friends" for High-Eccentricity Migration -- A Stringent Upper Limit on the Perturber's Separation

    CERN Document Server

    Dong, Subo; Socrates, Aristotle

    2013-01-01

    We propose a stringent observational test on the formation of warm Jupiters (gas-giant planets with 10d ~ 50% of those with large eccentricities (e>0.4) have known close Jovian companions satisfying the constraint required for high-e migration. In contrast, <~ 20% of the low-e (e<0.2) warm Jupiters have detected additional Jovian companions, implying that high-e migration with planetary perturbers is not the dominant channel in forming such planets. Complete, long-term RV follow-ups of the warm-Jupiter population will allow a firm upper limit to be put on the fraction of these planets formed by high-e migration. In the future, transiting warm Jupiters suitable for spin-orbit alignment measurements are expected to be discovered, and mis-aligned warm Jupiters will be particularly interesting candidates to apply our observational test. If the spin-orbit misalignments detected for transiting hot Jupiters are solely due to high-e migration as commonly suggested, we expect that the majority of warm Jupiters w...

  8. Orphan Toxin OrtT (YdcX of Escherichia coli Reduces Growth during the Stringent Response

    Directory of Open Access Journals (Sweden)

    Sabina Islam

    2015-01-01

    Full Text Available Toxin/antitoxin (TA systems are nearly universal in prokaryotes; toxins are paired with antitoxins which inactivate them until the toxins are utilized. Here we explore whether toxins may function alone; i.e., whether a toxin which lacks a corresponding antitoxin (orphan toxin is physiologically relevant. By focusing on a homologous protein of the membrane-damaging toxin GhoT of the Escherichia coli GhoT/GhoS type V TA system, we found that YdcX (renamed OrtT for orphan toxin related to tetrahydrofolate is toxic but is not part of TA pair. OrtT is not inactivated by neighboring YdcY (which is demonstrated to be a protein, nor is it inactivated by antitoxin GhoS. Also, OrtT is not inactivated by small RNA upstream or downstream of ortT. Moreover, screening a genomic library did not identify an antitoxin partner for OrtT. OrtT is a protein and its toxicity stems from membrane damage as evidenced by transmission electron microscopy and cell lysis. Furthermore, OrtT reduces cell growth and metabolism in the presence of both antimicrobials trimethoprim and sulfamethoxazole; these antimicrobials induce the stringent response by inhibiting tetrahydrofolate synthesis. Therefore, we demonstrate that OrtT acts as an independent toxin to reduce growth during stress related to amino acid and DNA synthesis.

  9. Enhanced stabilization of a stable single domain antibody for SEB toxin by random mutagenesis and stringent selection.

    Science.gov (United States)

    Turner, Kendrick B; Zabetakis, Dan; Goldman, Ellen R; Anderson, George P

    2014-03-01

    Single domain antibodies, recombinant variable heavy domains derived from the unique heavy-chain only antibodies found in camelids and sharks, are exceptionally rugged due to their ability to refold following heat or chemical denaturation. In addition, a number of single domain antibodies have been found to possess high melting points which provide an even greater degree of stability; one of these, llama-derived A3, is a binder of Staphylococcal enterotoxin B and has a Tm of 83.5 °C. In this work, we utilized random mutagenesis and stringent selection in an effort to obtain variants of A3 with even higher melting points. This effort resulted in the selection of a double mutant, A3-T28I-S72I, which has a melting point of 90.0 °C and near wild-type affinity for the target antigen. We further characterized the mutations individually to determine that while both contributed to the thermal stabilization, the T28I mutation accounted for ∼ 4.1 °C of the 6.5 °C increase. This work demonstrates that by the addition of relatively subtle changes it is possible to further improve the melting temperature of single domain antibodies that are already remarkably stable.

  10. Performance evaluation of an advanced air-fuel ratio controller on a stationary, rich-burn natural gas engine

    Science.gov (United States)

    Kochuparampil, Roshan Joseph

    The advent of an era of abundant natural gas is making it an increasingly economical fuel source against incumbents such as crude oil and coal, in end-use sectors such as power generation, transportation and industrial chemical production, while also offering significant environmental benefits over these incumbents. Equipment manufacturers, in turn, are responding to widespread demand for power plants optimized for operation with natural gas. In several applications such as distributed power generation, gas transmission, and water pumping, stationary, spark-ignited, natural gas fueled internal combustion engines (ICEs) are the power plant of choice (over turbines) owing to their lower equipment and operational costs, higher thermal efficiencies across a wide load range, and the flexibility afforded to end-users when building fine-resolution horsepower topologies: modular size increments ranging from 100 kW -- 2 MW per ICE power plant compared to 2 -- 5 MW per turbine power plant. Under the U.S. Environment Protection Agency's (EPA) New Source Performance Standards (NSPS) and Reciprocating Internal Combustion Engine National Emission Standards for Hazardous Air Pollutants (RICE NESHAP) air quality regulations, these natural gas power plants are required to comply with stringent emission limits, with several states mandating even stricter emissions norms. In the case of rich-burn or stoichiometric natural gas ICEs, very high levels of sustained emissions reduction can be achieved through exhaust after-treatment that utilizes Non Selective Catalyst Reduction (NSCR) systems. The primary operational constraint with these systems is the tight air-fuel ratio (AFR) window of operation that needs to be maintained if the NSCR system is to achieve simultaneous reduction of carbon monoxide (CO), nitrogen oxides (NOx), total hydrocarbons (THC), volatile organic compounds (VOCs), and formaldehyde (CH 2O). Most commercially available AFR controllers utilizing lambda (oxygen

  11. Quadruple suspension design for Advanced LIGO

    Energy Technology Data Exchange (ETDEWEB)

    Robertson, N A; Cagnoli, G; Crooks, D R M; Elliffe, E; Grant, A; Heptonstall, A; Hough, J; Perreur-Lloyd, M; Plissi, M V; Rowan, S; Sneddon, P H; Strain, K A; Torrie, C I; Ward, H [Department of Physics and Astronomy, University of Glasgow, Glasgow G12 8QQ (United Kingdom); Faller, J E [JILA, NIST and University of Colorado, Boulder, CO 80309 (United States); Fritschel, P [LIGO Laboratory, Massachusetts Institute of Technology, 175 Albany St, Cambridge, MA 02139 (United States); Gossler, S [Universitat Hannover, Institut fuer Atom und Molekuelphysik, Abteilung Spektroskopie, D30167, Hannover (Germany); Lueck, H [Universitat Hannover, Institut fuer Atom und Molekuelphysik, Abteilung Spektroskopie, D30167, Hannover (Germany); Mittleman, R [LIGO Laboratory, Massachusetts Institute of Technology, 175 Albany St, Cambridge, MA 02139 (United States); Shoemaker, D H [LIGO Laboratory, Massachusetts Institute of Technology, 175 Albany St, Cambridge, MA 02139 (United States); Willems, P [LIGO Laboratory, California Institute of Technology, MS 18-34, Pasadena, CA 91125 (United States)

    2002-08-07

    In this paper, we describe the conceptual design for the suspension system for the test masses for Advanced LIGO, the planned upgrade to LIGO, the US laser interferometric gravitational-wave observatory. The design is based on the triple pendulum design developed for GEO 600 - the German/UK interferometric gravitational wave detector. The GEO design incorporates fused silica fibres of circular cross-section attached to the fused silica mirror (test mass) in the lowest pendulum stage, in order to minimize the thermal noise from the pendulum modes. The damping of the low-frequency modes of the triple pendulum is achieved by using co-located sensors and actuators at the highest mass of the triple pendulum. Another feature of the design is that global control forces acting on the mirrors, used to maintain the output of the interferometer on a dark fringe, are applied via a triple reaction pendulum, so that these forces can be implemented via a seismically isolated platform. These techniques have been extended to meet the more stringent noise levels planned for in Advanced LIGO. In particular, the Advanced LIGO baseline design requires a quadruple pendulum with a final stage consisting of a 40 kg sapphire mirror, suspended on fused silica ribbons or fibres. The design is chosen to aim to reach a target noise contribution from the suspension corresponding to a displacement sensitivity of 10{sup -19} m Hz{sup -1/2} at 10 Hz at each of the test masses.

  12. Land Surface Microwave Emissivities Derived from AMSR-E and MODIS Measurements with Advanced Quality Control

    Science.gov (United States)

    Moncet, Jean-Luc; Liang, Pan; Galantowicz, John F.; Lipton, Alan E.; Uymin, Gennady; Prigent, Catherine; Grassotti, Christopher

    2011-01-01

    A microwave emissivity database has been developed with data from the Advanced Microwave Scanning Radiometer-EOS (AMSR-E) and with ancillary land surface temperature (LST) data from the Moderate Resolution Imaging Spectroradiometer (MODIS) on the same Aqua spacecraft. The primary intended application of the database is to provide surface emissivity constraints in atmospheric and surface property retrieval or assimilation. An additional application is to serve as a dynamic indicator of land surface properties relevant to climate change monitoring. The precision of the emissivity data is estimated to be significantly better than in prior databases from other sensors due to the precise collocation with high-quality MODIS LST data and due to the quality control features of our data analysis system. The accuracy of the emissivities in deserts and semi-arid regions is enhanced by applying, in those regions, a version of the emissivity retrieval algorithm that accounts for the penetration of microwave radiation through dry soil with diurnally varying vertical temperature gradients. These results suggest that this penetration effect is more widespread and more significant to interpretation of passive microwave measurements than had been previously established. Emissivity coverage in areas where persistent cloudiness interferes with the availability of MODIS LST data is achieved using a classification-based method to spread emissivity data from less-cloudy areas that have similar microwave surface properties. Evaluations and analyses of the emissivity products over homogeneous snow-free areas are presented, including application to retrieval of soil temperature profiles. Spatial inhomogeneities are the largest in the vicinity of large water bodies due to the large water/land emissivity contrast and give rise to large apparent temporal variability in the retrieved emissivities when satellite footprint locations vary over time. This issue will be dealt with in the future by

  13. Recent advances in automotive catalysis for NOx emission control by small-pore microporous materials

    Energy Technology Data Exchange (ETDEWEB)

    Beale, Andrew M.; Gao, Feng; Lezcano-Gonzalez, Ines; Peden, Charles HF; Szanyi, Janos

    2015-10-05

    The ever increasing demand to develop highly fuel efficient engines coincides with the need to minimize air pollution originating from the exhaust gases of internal combustion engines. Dramatically improved fuel efficiency can be achieved at air-to-fuel ratios much higher than stoichiometric. In the presence of oxygen in large excess, however, traditional three-way catalysts are unable to reduce NOx. Among the number of lean-NOx reduction technologies, selective catalytic reduction (SCR) of NOx by NH3 over Cu- and Fe-ion exchanged zeolite catalysts has been extensively studied over the past 30+ years. Despite the significant advances in developing a viable practical zeolite-based catalyst for lean NOx reduction, the insufficient hydrothermal stabilities of the zeolite structures considered cast doubts about their real-world applicability. During the past decade a renewed interest in zeolite-based lean NOx reduction was spurred by the discovery of the very high activity of Cu-SSZ-13 (and the isostructural Cu-SAPO-34) in the NH3 SCR of NOx. These new, small-pore zeolite-based catalysts not only exhibited very high NOx conversion and N2 selectivity, but also exhibited exceptional high hydrothermal stability at high temperatures. In this review we summarize the key discoveries of the past ~5 years that lead to the introduction of these catalysts into practical application. The review first briefly discusses the structure and preparation of the CHA structure-based zeolite catalysts, and then summarizes the key learnings of the rather extensive (but not complete) characterisation work. Then we summarize the key findings of reaction kinetics studies, and provide some mechanistic details emerging from these investigations. At the end of the review we highlight some of the issues that are still need to be addressed in automotive exhaust control catalysis. Funding A.M.B. and I.L.G. would like to thank EPSRC for funding. F.G., C.H.F.P. and J.Sz. gratefully acknowledge

  14. Land Surface Microwave Emissivities Derived from AMSR-E and MODIS Measurements with Advanced Quality Control

    Science.gov (United States)

    Moncet, Jean-Luc; Liang, Pan; Galantowicz, John F.; Lipton, Alan E.; Uymin, Gennady; Prigent, Catherine; Grassotti, Christopher

    2011-01-01

    A microwave emissivity database has been developed with data from the Advanced Microwave Scanning Radiometer-EOS (AMSR-E) and with ancillary land surface temperature (LST) data from the Moderate Resolution Imaging Spectroradiometer (MODIS) on the same Aqua spacecraft. The primary intended application of the database is to provide surface emissivity constraints in atmospheric and surface property retrieval or assimilation. An additional application is to serve as a dynamic indicator of land surface properties relevant to climate change monitoring. The precision of the emissivity data is estimated to be significantly better than in prior databases from other sensors due to the precise collocation with high-quality MODIS LST data and due to the quality control features of our data analysis system. The accuracy of the emissivities in deserts and semi-arid regions is enhanced by applying, in those regions, a version of the emissivity retrieval algorithm that accounts for the penetration of microwave radiation through dry soil with diurnally varying vertical temperature gradients. These results suggest that this penetration effect is more widespread and more significant to interpretation of passive microwave measurements than had been previously established. Emissivity coverage in areas where persistent cloudiness interferes with the availability of MODIS LST data is achieved using a classification-based method to spread emissivity data from less-cloudy areas that have similar microwave surface properties. Evaluations and analyses of the emissivity products over homogeneous snow-free areas are presented, including application to retrieval of soil temperature profiles. Spatial inhomogeneities are the largest in the vicinity of large water bodies due to the large water/land emissivity contrast and give rise to large apparent temporal variability in the retrieved emissivities when satellite footprint locations vary over time. This issue will be dealt with in the future by

  15. Advanced Instrumentation, Information, and Control Systems Technologies Pathway: FY 2016 External Review

    Energy Technology Data Exchange (ETDEWEB)

    Thomas, Kenneth David [Idaho National Lab. (INL), Idaho Falls, ID (United States); Hallbert, Bruce Perry [Idaho National Lab. (INL), Idaho Falls, ID (United States)

    2016-11-01

    This report describes an External Review conducted by the LWRS Program Advanced Instrumentation, Information, and Control (II&C) Systems Technologies Pathway to solicit feedback on the topics and results of the ongoing II&C research program. This review was held in conjunction with the Nuclear Energy Institute (NEI) Digital I&C Working Group meeting that was held at Idaho National Laboratory (INL) on August 9-10, 2016. Given the opportunity to visit INL and see the pathway research projects, NEI agreed that the Working Group would serve as the External Review panel for the purpose of obtaining expert input on the value and timing of the research projects. This consisted of demonstrations in the Human Systems Simulation Laboratory followed by presentations on the II&C research program in general as well as the five technology development areas. Following the meeting, the presentations were sent to each of the attendees so they could review them in more detail and refer to them in completing the feedback form. Follow-up activities were conducted with the attendees following the meeting to obtain the completed feedback forms. A total of 13 forms were returned. The feedback forms were reviewed by the pathway to compile the data and comments received, which are documented in the report. In all, the feedback provided by the External Review participants is taken to be a strong endorsement of the types of projects being conducted by the pathway, the value they hold for the nuclear plants, and the general timing of need. The feedback aligns well with the priorities, levels of efforts allocated for the research projects, and project schedules. The feedback also represents realistic observations on the practicality of some aspects of implementing these technologies. In some cases, the participants provided thoughtful challenges to certain assumptions in the formulation of the technologies or in deployment plans. These deserve further review and revision of plans if warranted

  16. Transient Load Following and Control Analysis of Advanced S-CO2 Power Conversion with Dry Air Cooling

    Energy Technology Data Exchange (ETDEWEB)

    Moisseytsev, Anton; Sienicki, James J.

    2016-01-01

    Supercritical carbon dioxide (S-CO2) Brayton cycles are under development as advanced energy converters for advanced nuclear reactors, especially the Sodium-Cooled Fast Reactor (SFR). The use of dry air cooling for direct heat rejection to the atmosphere ultimate heat sink is increasingly becoming a requirement in many regions due to restrictions on water use. The transient load following and control behavior of an SFR with an S-CO2 cycle power converter utilizing dry air cooling have been investigated. With extension and adjustment of the previously existing control strategy for direct water cooling, S-CO2 cycle power converters can also be used for load following operation in regions where dry air cooling is a requirement

  17. A survey on the development of advanced instrumentation and control system in NPP

    Energy Technology Data Exchange (ETDEWEB)

    Ham, Chang Sik; Kwon, Kee Choon; Chung, Chul Hwan [Korea Atomic Energy Research Institute, Taejon (Korea, Republic of)

    1993-12-01

    Many developed countries are improving or operating the advanced I and C systems of NPPs. They are: (1) N4 of EDF in France, (2) AP 600 of Westinghouse in USA, (3) NUPLEX-80+ of ABB-CE in USA, (4) CANDU in Canada, (5) Ohi 3 and 4, APWR and ABWR in Japan, (6) Belt-D in Germany, (7) Sizewell B in Britain, (8) Halden Reactor Projector in Norway, (9) I and C systems in Russia and Eastern Europe. This report describes the development trend, background, system architecture, characteristics with the new safety concerns, licensing problems, future plan, and retrofit experiences of these advanced nuclear I and C systems. The biggest difference between the existing systems and the advanced systems is the application of software rather than hardware for the functional implementation. All of the improved I and C systems accepted the standard modules and off-the shelf devices. Their characteristics are focused on EPRI URD Chapter 10. (author).

  18. PEM Fuel Cells with Bio-Ethanol Processor Systems A Multidisciplinary Study of Modelling, Simulation, Fault Diagnosis and Advanced Control

    CERN Document Server

    Feroldi, Diego; Outbib, Rachid

    2012-01-01

    An apparently appropriate control scheme for PEM fuel cells may actually lead to an inoperable plant when it is connected to other unit operations in a process with recycle streams and energy integration. PEM Fuel Cells with Bio-Ethanol Processor Systems presents a control system design that provides basic regulation of the hydrogen production process with PEM fuel cells. It then goes on to construct a fault diagnosis system to improve plant safety above this control structure. PEM Fuel Cells with Bio-Ethanol Processor Systems is divided into two parts: the first covers fuel cells and the second discusses plants for hydrogen production from bio-ethanol to feed PEM fuel cells. Both parts give detailed analyses of modeling, simulation, advanced control, and fault diagnosis. They give an extensive, in-depth discussion of the problems that can occur in fuel cell systems and propose a way to control these systems through advanced control algorithms. A significant part of the book is also given over to computer-aid...

  19. From computer-aided to intelligent machining:\\ud Recent advances in computer numerical control machining research

    OpenAIRE

    Gao, James; Lee, Chen-Han; Li, Yingguagan

    2015-01-01

    The aim of this paper is to provide an introduction and overview of recent advances in the key technologies and the supporting computerized systems, and to indicate the trend of research and development in the area of computational numerical control machining. Three main themes of recent research in CNC machining are simulation, optimization and automation, which form the key aspects of intelligent manufacturing in the digital and knowledge based manufacturing era. As the information and know...

  20. Conversion of the dual training aircraft (DC into single control advanced training aircraft (SC. Part I

    Directory of Open Access Journals (Sweden)

    Ioan ŞTEFĂNESCU

    2011-03-01

    Full Text Available Converting the DC school jet aircraft into SC advanced training aircraft - and use them forthe combat training of military pilots from the operational units, has become a necessity due to thebudget cuts for Air Force, with direct implications on reducing the number of hours of flight assignedto operating personnel for preparing and training.The purpose of adopting such a program is to reduce the number of flight hours allocated annuallyfor preparing and training in advanced stages of instruction, for every pilot, by more intensive use ofthis type of aircraft, which has the advantage of lower flight hour costs as compared to a supersoniccombat plane.