WorldWideScience

Sample records for adults current standards

  1. Nuclear standards: current issues and future trends

    International Nuclear Information System (INIS)

    A summary of the important issues that currently face the nuclear standards field is presented and a discussion of how each of these issues is being resolved is given. The economic benefits that properly developed standards produce are listed

  2. Standards for Adult Education ESL Programs

    Science.gov (United States)

    TESOL Press, 2013

    2013-01-01

    What are the components of a quality education ESL program? TESOL's "Standards for Adult Education ESL Programs" answers this question by defining quality components from a national perspective. Using program indicators in eight distinct areas, the standards can be used to review an existing program or as a guide in setting up a new…

  3. A review of the quantum current standard

    Science.gov (United States)

    Kaneko, Nobu-Hisa; Nakamura, Shuji; Okazaki, Yuma

    2016-03-01

    The electric current, voltage, and resistance standards are the most important standards related to electricity and magnetism. Of these three standards, only the ampere, which is the unit of electric current, is an International System of Units (SI) base unit. However, even with modern technology, relatively large uncertainty exists regarding the generation and measurement of current. As a result of various innovative techniques based on nanotechnology and novel materials, new types of junctions for quantum current generation and single-electron current sources have recently been proposed. These newly developed methods are also being used to investigate the consistency of the three quantum electrical effects, i.e. the Josephson, quantum Hall, and single-electron tunneling effects, which are also known as ‘the quantum metrology triangle’. This article describes recent research and related developments regarding current standards and quantum-metrology-triangle experiments.

  4. A review of the quantum current standard

    International Nuclear Information System (INIS)

    The electric current, voltage, and resistance standards are the most important standards related to electricity and magnetism. Of these three standards, only the ampere, which is the unit of electric current, is an International System of Units (SI) base unit. However, even with modern technology, relatively large uncertainty exists regarding the generation and measurement of current. As a result of various innovative techniques based on nanotechnology and novel materials, new types of junctions for quantum current generation and single-electron current sources have recently been proposed. These newly developed methods are also being used to investigate the consistency of the three quantum electrical effects, i.e. the Josephson, quantum Hall, and single-electron tunneling effects, which are also known as ‘the quantum metrology triangle’. This article describes recent research and related developments regarding current standards and quantum-metrology-triangle experiments. (topical review)

  5. Current work on dosimetry standards in Japan

    International Nuclear Information System (INIS)

    Basic concepts on standardization of radiation dosimetry are reviewed. The present situation regarding primary standards in the Electrotechnical Laboratory, the primary standard dosimetry laboratory in Japan, is presented, considering the following; (i) Established dosimetric standards of exposure for soft and medium-energy X-rays and gamma rays. This section includes methods of their standardization, and discusses accuracies of instruments operating as environmental-level, protection-level, inspection-level, therapy-level, and processing-level measuring systems. The results of international comparisons between ETL and other, foreign primary standard dosimetry laboratories are presented; (ii) Other established radiation standards related to derivation of radiation absorbed dose. These primary standards include those for the neutron emission rates, thermal and fast neutron flux densities, energy fluences for high-energy photons and electrons, and activities of several kinds of radioactive material. The accuracies and results of international comparisons relating to them are also presented; (iii) Research being carried out at ETL. The current status of the dissemination of radiation standards is presented considering in particular: (i) The calibration services available at ETL, the categories of these services, energy and dose rate ranges, methods, accuracies, etc.; (ii) The calibration services available in certain other organizations considered as SSDLs in Japan, the categories of such work, methods, accuracies etc.; (iii) Present endeavours towards establishing a systematic and effective dissemination system (a so-called Traceability System) in Japan

  6. Adult Cigarette Smoking in the United States: Current Estimates

    Science.gov (United States)

    ... Health More CDC Sites Current Cigarette Smoking Among Adults in the United States Recommend on Facebook Tweet ... every day or some days. Current Smoking Among Adults in 2014 (Nation) By Gender 1 Men are ...

  7. Mitogenome metadata: current trends and proposed standards.

    Science.gov (United States)

    Strohm, Jeff H T; Gwiazdowski, Rodger A; Hanner, Robert

    2016-09-01

    Mitogenome metadata are descriptive terms about the sequence, and its specimen description that allow both to be digitally discoverable and interoperable. Here, we review a sampling of mitogenome metadata published in the journal Mitochondrial DNA between 2005 and 2014. Specifically, we have focused on a subset of metadata fields that are available for GenBank records, and specified by the Genomics Standards Consortium (GSC) and other biodiversity metadata standards; and we assessed their presence across three main categories: collection, biological and taxonomic information. To do this we reviewed 146 mitogenome manuscripts, and their associated GenBank records, and scored them for 13 metadata fields. We also explored the potential for mitogenome misidentification using their sequence diversity, and taxonomic metadata on the Barcode of Life Datasystems (BOLD). For this, we focused on all Lepidoptera and Perciformes mitogenomes included in the review, along with additional mitogenome sequence data mined from Genbank. Overall, we found that none of 146 mitogenome projects provided all the metadata we looked for; and only 17 projects provided at least one category of metadata across the three main categories. Comparisons using mtDNA sequences from BOLD, suggest that some mitogenomes may be misidentified. Lastly, we appreciate the research potential of mitogenomes announced through this journal; and we conclude with a suggestion of 13 metadata fields, available on GenBank, that if provided in a mitogenomes's GenBank record, would increase their research value. PMID:25693692

  8. Standard guidelines for electrosurgery with radiofrequency current

    OpenAIRE

    Mutalik Sharad

    2009-01-01

    Definition: Radiofrequency (RF) induces thermal destruction of the targeted tissue by an electrical current at a frequency of 0.5 MHz (RF). As the electrode tip is not heated, there is minimal thermal damage to the surrounding tissues, producing good esthetic results. Therefore, RF ablation is also known as cold ablation or "coblation." Modality: It has three modes of operation: (a) Cut, (b) cut and coagulate and (c) coagulate. Therefore, it can be used for various purposes like incision, ...

  9. 78 FR 46589 - Solicitation of Written Comments on the Draft Report of the National Adult Immunization Standards...

    Science.gov (United States)

    2013-08-01

    ... HUMAN SERVICES Solicitation of Written Comments on the Draft Report of the National Adult Immunization... Director of the National Vaccine Program. The ASH has charged the NVAC with examining the current adult immunization environment by updating adult immunization standards of practice with the intention of...

  10. Current Cigarette Use Among Adults (BRFSS) PDF Slides

    Data.gov (United States)

    U.S. Department of Health & Human Services — Download the current cigarette use among adults slides. These slides are available in PDF and PowerPoint formats. The PowerPoint version can be found at:...

  11. Standard guidelines for electrosurgery with radiofrequency current

    Directory of Open Access Journals (Sweden)

    Mutalik Sharad

    2009-08-01

    Full Text Available Definition: Radiofrequency (RF induces thermal destruction of the targeted tissue by an electrical current at a frequency of 0.5 MHz (RF. As the electrode tip is not heated, there is minimal thermal damage to the surrounding tissues, producing good esthetic results. Therefore, RF ablation is also known as cold ablation or "coblation." Modality: It has three modes of operation: (a Cut, (b cut and coagulate and (c coagulate. Therefore, it can be used for various purposes like incision, ablation, fulguration, shave excision and coagulation. Because of the coagulation facility, hemostasis can be achieved and operation becomes easier and faster. Indications: It is effective in treating various skin conditions like dermatosis papulosa nigra, warts, molluscum contagiosum, colloid milia, acquired junctional, compound and dermal melanocytic nevi, seborrheic keratosis, skin tags, granuloma pyogenicum, verrucous epidermal nevi, xanthelesma, rhinophyma, superficial basal cell carcinoma and telangiectasia. It can also be used for cosmetic indications such as resurfacing, earlobe repair and blepharoplasty. Anesthesia: The procedure is accomplished either under topical anesthesia eutactic mixture of local anesthetics or local injectable anesthesia, under all aseptic precautions. Procedure: While operating, only the tip of the electrode should come in contact with the tissue. Actual contact of the electrode with the tissue should be very brief in order to prevent excessive damage to the deeper tissues. This can be accomplished by moving the electrode quickly. Complications: Complications are uncommon and mainly occur due to an improper technique. The treating physician should be aware of the contraindications of the procedure as listed in these guidelines. Physician qualification: RF surgery may be performed by a dermatologist who has acquired adequate training during post-graduation or through recognized fellowships and workshops dedicated to RF surgery. He

  12. Current Status and Future Prospects of Hydroelectricity Standardization

    Institute of Scientific and Technical Information of China (English)

    2010-01-01

    Technical standardization is very essential to electricity industry, which plays an active role in many aspects including technology standardization, secure and economic operation of power systems, environment protection, technological progress, and improvement of enterprises' management. This paper introduces the current status of hydroelectricity standardization, summarizes the progress and achievements, and then points out the development direction and working target in the future.

  13. Current Status and Future Prospects of Hydroelectricity Standardization

    Institute of Scientific and Technical Information of China (English)

    Liu Yongdong

    2010-01-01

    @@ Technical standardization is very essential to electricity industry, which plays an active role in many aspects including technology standardization, secure and economic operation of power systems, environment protection, technological progress, and improvement of enterprises' management. This paper introduces the current status of hydroelectricity standardization, summarizes the progress and achievements, and then points out the development direction and working target in the future.

  14. [Cephalometric standards of adult Greeks (Ricketts' ten factor analysis)].

    Science.gov (United States)

    Kavadia, S; Topouzelis, N; Sidiropoulou, S; Markovitsi, H; Kolokythas, G

    1989-09-01

    In this study the ten factors which compose the Ricketts' summary analysis were measured on 81 lateral skull radiographs of adult Greeks (41 males and 40 females) with normal occlusion and harmonious face to establish cephalometric standards. The mean value, standard deviation, standard error of the mean, minimum and maximum values as well as the range of each variable were found and discussed for each sex separately as well as for the whole sample. The main conclusion of the study is that adult Greeks with normal occlusion and harmonious face present: a tendency to the brachy facial vertical type, a small retroposition of the maxilla and of the lower lip and prominent and labialy proclined lower incisors.

  15. Adult Current Smoking: Differences in Definitions and Prevalence Estimates—NHIS and NSDUH, 2008

    Directory of Open Access Journals (Sweden)

    Heather Ryan

    2012-01-01

    Full Text Available Objectives. To compare prevalence estimates and assess issues related to the measurement of adult cigarette smoking in the National Health Interview Survey (NHIS and the National Survey on Drug Use and Health (NSDUH. Methods. 2008 data on current cigarette smoking and current daily cigarette smoking among adults ≥18 years were compared. The standard NHIS current smoking definition, which screens for lifetime smoking ≥100 cigarettes, was used. For NSDUH, both the standard current smoking definition, which does not screen, and a modified definition applying the NHIS current smoking definition (i.e., with screen were used. Results. NSDUH consistently yielded higher current cigarette smoking estimates than NHIS and lower daily smoking estimates. However, with use of the modified NSDUH current smoking definition, a notable number of subpopulation estimates became comparable between surveys. Younger adults and racial/ethnic minorities were most impacted by the lifetime smoking screen, with Hispanics being the most sensitive to differences in smoking variable definitions among all subgroups. Conclusions. Differences in current cigarette smoking definitions appear to have a greater impact on smoking estimates in some sub-populations than others. Survey mode differences may also limit intersurvey comparisons and trend analyses. Investigators are cautioned to use data most appropriate for their specific research questions.

  16. Current Concepts: Laser Treatment of Adult Vascular Lesions

    OpenAIRE

    Wall, Tomi L.

    2007-01-01

    Patients frequently seek treatment of cutaneous vascular lesions for both medical and cosmetic reasons. Advances in the use of lasers and light sources enable physicians to effectively treat vascular lesions that were previously untreatable. Given the plethora of devices available, selecting the appropriate laser system and treatment parameters can be confusing for the laser surgeon. This article reviews current concepts in the treatment of adult vascular conditions. It highlights the differe...

  17. Latent autoimmune diabetes of the adult: current knowledge and uncertainty

    Science.gov (United States)

    Laugesen, E; Østergaard, J A; Leslie, R D G

    2015-01-01

    Patients with adult-onset autoimmune diabetes have less Human Leucocyte Antigen (HLA)-associated genetic risk and fewer diabetes-associated autoantibodies compared with patients with childhood-onset Type 1 diabetes. Metabolic changes at diagnosis reflect a broad clinical phenotype ranging from diabetic ketoacidosis to mild non-insulin-requiring diabetes, also known as latent autoimmune diabetes of the adult (LADA). This latter phenotype is the most prevalent form of adult-onset autoimmune diabetes and probably the most prevalent form of autoimmune diabetes in general. Although LADA is associated with the same genetic and immunological features as childhood-onset Type 1 diabetes, it also shares some genetic features with Type 2 diabetes, which raises the question of genetic heterogeneity predisposing to this form of the disease. The potential value of screening patients with adult-onset diabetes for diabetes-associated autoantibodies to identify those with LADA is emphasized by their lack of clinically distinct features, their different natural history compared with Type 2 diabetes and their potential need for a dedicated management strategy. The fact that, in some studies, patients with LADA show worse glucose control than patients with Type 2 diabetes, highlights the need for further therapeutic studies. Challenges regarding classification, epidemiology, genetics, metabolism, immunology, clinical presentation and treatment of LADA were discussed at a 2014 workshop arranged by the Danish Diabetes Academy. The presentations and discussions are summarized in this review, which sets out the current ideas and controversies surrounding this form of diabetes. What’s new? Latent autoimmune diabetes of the adult (LADA) is an autoimmune diabetes defined by adult-onset, presence of diabetes associated autoantibodies, and no insulin treatment requirement for a period after diagnosis. Immunologically, glutamic acid decarboxylase 65 autoantibodies are by far the most

  18. 25 CFR 20.335 - What is the payment standard for Adult Care Assistance?

    Science.gov (United States)

    2010-04-01

    ... 25 Indians 1 2010-04-01 2010-04-01 false What is the payment standard for Adult Care Assistance... FINANCIAL ASSISTANCE AND SOCIAL SERVICES PROGRAMS Direct Assistance Adult Care Assistance § 20.335 What is the payment standard for Adult Care Assistance? The approved payment for adult care assistance...

  19. Nuclear aspects of neutral current non-standard $\

    CERN Document Server

    Papoulias, D K

    2013-01-01

    The nuclear aspects of flavour changing neutral current (FCNC) processes, predicted by various new-physics models to occur in the presence of nuclei, are examined by computing the relevant nuclear matrix elements within the context of the quasi-particle RPA using realistic strong two-body forces. One of our aims is to explore the role of the non-standard interactions (NSI) in the leptonic sector and specifically: (i) in lepton flavour violating (LFV) processes involving the neutral particles $\

  20. Current lifestyle of young adults treated for cancer in childhood.

    Science.gov (United States)

    Evans, S E; Radford, M

    1995-05-01

    The aim of this study was to look at the current lifestyle of young adult survivors of childhood cancer between the ages of 16 and 30 years to document their achievements and expose any psychosocial problems. Sixty six young adult survivors were contacted and asked if they and their siblings (16-30 years) would take part in a lifestyle study; 48 patients and 38 sibling controls were interviewed. This took the form of a structured lifestyle questionnaire, a self esteem questionnaire (Oxford Psychologists Press), and an unstructured interview. Fifty five per cent of patients achieved five or more A-C grades at 'O' level/GCSE compared with 62% of siblings and a national average of 30%. Despite that these patients were significantly less likely to go on to higher education than their siblings. The two groups were equally employable and earning similar salaries. There were three cases of known employer prejudice. A slightly higher percentage of patients than siblings had their driving licence. Seventeen patients felt their appearance had changed and eight felt that they had a residual physical mobility problem. Both groups were socially active and equally likely to partake in competitive sports. There was no overall difference in the self esteem of the two groups. In general the survivors of childhood cancer were coping well in their young adult life and achieving the same lifestyle goals as their siblings. However, significant problems have been identified. PMID:7618909

  1. Evaluation of standard liver volume formulae for Chinese adults

    Institute of Scientific and Technical Information of China (English)

    Zheng-Rong Shi; Lu-Nan Yan; Bo Li; Tian-Fu Wen

    2009-01-01

    AIM:To evaluate different standard liver volume (SLV) formula and verify the applicability of the formulae for Chinese adults.METHODS:Data from 70 cases of living donor liver transplantation (LDLT) performed at our transplantation centers between January 2008 and April 2009 were analyzed.SLV was estimated using our recently reported formula [the Chengdu formula:SLV (mL) = 11.5×body weight (kg) + 334] and other reported formulae used for Chinese adults.Actual intraoperative liver volumes were obtained from a review of the patients' medical records.RESULTS:The actual right liver volume was not signifi-cantly different from the estimated right liver volume determined by the Chengdu formula,but was significantly smaller than estimates using the Heinemann,Urata,Vauthey,and Lee formulae (P<0.01),and significantly larger than estimates using the Fan formula (P<0.05).CONCLUSION:The Chengdu formula was demonstrated to be reliable by its application in LDLT.

  2. UV dose-effect relationships and current protection exposure standards

    International Nuclear Information System (INIS)

    In this paper we have attempted to quantify the health effects in man of uv-radiation exposure of wavelengths from 240 nm to 320 nm. Exposure to uv in this region could result in the formation of skin cancer or premature aging in man. The induction of cancer by uv radiation results from changes in genetic material. We have used the DNA action spectrum coupled with the uv skin cancer data available in the literature to derive the dose-effect relationships. The results are compared against the current uv protection standards

  3. Beyond standard model physics at current and future colliders

    Science.gov (United States)

    Liu, Zhen

    The Large Hadron Collider (LHC), a multinational experiment which began running in 2009, is highly expected to discover new physics that will help us understand the nature of the universe and begin to find solutions to many of the unsolved puzzles of particle physics. For over 40 years the Standard Model has been the accepted theory of elementary particle physics, except for one unconfirmed component, the Higgs boson. The experiments at the LHC have recently discovered this Standard-Model-like Higgs boson. This discovery is one of the most exciting achievements in elementary particle physics. Yet, a profound question remains: Is this rather light, weakly-coupled boson nothing but a Standard Model Higgs or a first manifestation of a deeper theory? Also, the recent discoveries of neutrino mass and mixing, experimental evidences of dark matter and dark energy, matter-antimatter asymmetry, indicate that our understanding of fundamental physics is currently incomplete. For the next decade and more, the LHC and future colliders will be at the cutting-edge of particle physics discoveries and will shed light on many of these unanswered questions. There are many promising beyond-Standard-Model theories that may help solve the central puzzles of particle physics. To fill the gaps in our knowledge, we need to know how these theories will manifest themselves in controlled experiments, such as high energy colliders. I discuss how we can probe fundamental physics at current and future colliders directly through searches for new phenomena such as resonances, rare Higgs decays, exotic displaced signatures, and indirectly through precision measurements on Higgs in this work. I explore beyond standard model physics effects from different perspectives, including explicit models such as supersymmetry, generic models in terms of resonances, as well as effective field theory approach in terms of higher dimensional operators. This work provides a generic and broad overview of the physics

  4. Adult-onset Still's disease: current challenges and future prospects

    Directory of Open Access Journals (Sweden)

    Siddiqui M

    2016-03-01

    Full Text Available Mariam Siddiqui,1 Michael S Putman,2 Anisha B Dua,11Department of Rheumatology, 2Department of Internal Medicine, The University of Chicago Medical Center, Chicago, IL, USA Abstract: Adult-onset Still's disease (AOSD – a multi-systemic inflammatory condition characterized by high fevers, polyarthritis, an evanescent rash, and pharyngitis – has been a challenging condition to diagnose expediently and treat effectively. Questions remain regarding the underlying pathophysiology and etiology of AOSD. Pathognomonic diagnostic tests and reliable biomarkers remain undiscovered. Over the past decade, important progress has been made. Diagnostic criteria employing glycosylated ferritin have improved specificity. More important, novel biologic therapies have offered important clues to AOSD's underlying pathophysiology. Cytokine-specific biologic therapies have been instrumental in providing more effective treatment for disease refractory to conventional treatment. While IL-1 therapy has demonstrated efficacy in refractory disease, novel therapies targeting IL-6 and IL-18 show great promise and are currently under investigation. Keywords: adult-onset Still's disease, biomarkers, therapeutics

  5. Validation of the ultrastable low-noise current amplifier as travelling standard for small direct currents

    CERN Document Server

    Drung, Dietmar; Giblin, Stephen P; Djordjevic, Sophie; Piquemal, Francois; Séron, Olivier; Rengnez, Florentin; Götz, Martin; Pesel, Eckart; Scherer, Hansjörg

    2015-01-01

    An interlaboratory comparison of small-current generation and measurement capability is presented with the ultrastable low-noise current amplifier (ULCA) acting as travelling standard. Various measurements at direct currents between 0.16 nA and 13 nA were performed to verify the degree of agreement between the three national metrology institutes involved in the study. Consistency well within one part per million (ppm) was found. Due to harsh environmental conditions during shipment, the ULCA's transfer accuracy had been limited to about +/-0.4 ppm. Supplemental measurements performed at PTB indicate that further improvements in accuracy are possible. Relative uncertainties of 0.1 ppm are achieved by applying on-site calibration of the ULCA with a suitable cryogenic current comparator.

  6. Current safety standards in infant nutrition--a European perspective.

    Science.gov (United States)

    Hernell, Olle

    2012-01-01

    Foods intended specifically for infants and young children are considered under European community law and are defined in specific commission directives. In principal, these directives conclude that such foods must be safe, have a special composition, be distinguishable from normal foods, be suitable for fulfilling particular nutritional requirements, and should, when marketed, indicate such suitability. Since infant formulas are intended as the sole source of nutrition during the first months of life, their nutritional adequacy and safety are particularly strictly regulated. The Scientific Committee on Food report from 2003, on which the current commission directive is based, makes clear recommendations on how benefits, suitability, and safety of modifications beyond established standards should be documented and evaluated. These principles resulted in part from a workshop on characterization of infant food modifications in the EU and two position papers by the European Society for Pediatric Gastroenterology, Hepatology and Nutrition (ESPGHAN). These papers are reviewed below.

  7. Connecting the Canon to Current Young Adult Literature

    Science.gov (United States)

    Rybakova, Katie; Roccanti, Rikki

    2016-01-01

    In this article we discuss the respective roles of young adult literature and literary texts in the secondary level English Language Arts classroom and explore the connections that can be made between popular young adult books and the traditional canon. We provide examples showing how young adult literature bestsellers such as "The Book…

  8. Document of standardization of enteral nutrition access in adults.

    Science.gov (United States)

    Arribas, Lorena; Frías, Laura; Creus, Gloria; Parejo, Juana; Urzola, Carmen; Ashbaugh, Rosana; Pérez-Portabella, Cleofé; Cuerda, Cristina

    2014-07-01

    The group of standardization and protocols of the Spanish Society of Parenteral and Enteral Nutrition (SENPE) published in 2011 a consensus document SENPE/SEGHNP/ANECIPN/SECP on enteral access for paediatric nutritional support. Along the lines of this document, we have developed another document on adult patients to homogenize the clinical practice and improve the quality of care in enteral access in this age group. The working group included health professionals (nurses, dietitians and doctor) with extensive experience in enteral nutrition and access. We tried to find scientific evidence through a literature review and we used the criteria of the Agency for Health-care Research and Quality (AHRQ) to classify the evidence (Grade of Recommendation A, B or C). Later the document was reviewed by external experts to the group and requested the endorsement of the Scientific and Educational Committee (CCE) and the group of home artificial nutrition (NADYA) of the SENPE. The full text will be published as a monograph number in this journal.

  9. Document of standardization of enteral nutrition access in adults

    Directory of Open Access Journals (Sweden)

    Lorena Arribas

    2014-07-01

    Full Text Available The group of standardization and protocols of the Spanish Society of Parenteral and Enteral Nutrition (SENPE published in 2011 a consensus document SENPE/SEGHNP/ANECIPN/SECP on enteral access for paediatric nutritional support. Along the lines of this document, we have developed another document on adult patients to homogenize the clinical practice and improve the quality of care in enteral access in this age group. The working group included health professionals (nurses, dietitians and doctor with extensive experience in enteral nutrition and access. We tried to find scientific evidence through a literature review and we used the criteria of the Agency for Health-care Research and Quality (AHRQ to classify the evidence (Grade of Recommendation A, B or C. Later the document was reviewed by external experts to the group and requested the endorsement of the Scientific and Educational Committee (CCE and the group of home artificial nutrition (NADYA of the SENPE. The full text will be published as a monograph number in this journal.

  10. 78 FR 33393 - Petition Requesting a Ban or Standard on Adult Portable Bed Rails

    Science.gov (United States)

    2013-06-04

    ... COMMISSION Petition Requesting a Ban or Standard on Adult Portable Bed Rails AGENCY: Consumer Product Safety... Safety Act (CPSA) to determine that adult portable bed rails pose an unreasonable risk of injury and... (CPSA) to determine that adult portable bed rails pose an unreasonable risk of injury and...

  11. Open Augmented Reality Standards: Current Activities in Standards- Development Organizations%Open Augmented Reality Standards: Current Activities in Standards- Development Organizations

    Institute of Scientific and Technical Information of China (English)

    Christine Perey

    2012-01-01

    Augmented reality (AR) has emerged from research laboratories and is now being accepted in other domains as an attractive way of visualizing information. Before AR can be used in the mass market, there are a number of obstacles that need to be overcome. Several of these can be overcome by adopting open standards. A global grassroots community seeking open, interoperable AR content and experiences began to take shape in early 2010. This community is working collaboratively to reduce the barriers to the flow of data from content provider to AR end user. Standards development organizations and industry groups that provide open interfaces for AR meet regularly to provide updates, identify complementary work, and seek harmonization. The community also identifies deployer and implementer needs, communicates requirements, and discusses emerging challenges that could be resolved with standards. In this article, we describe current activities in international standards-development organizations. We summarize the AR standards gap analysis and shed light on special considerations for using standards in mobile AR.

  12. Latent autoimmune diabetes of the adult: current knowledge and uncertainty

    OpenAIRE

    Laugesen, E; Østergaard, J A; Leslie, R D G

    2015-01-01

    Patients with adult-onset autoimmune diabetes have less Human Leucocyte Antigen (HLA)-associated genetic risk and fewer diabetes-associated autoantibodies compared with patients with childhood-onset Type 1 diabetes. Metabolic changes at diagnosis reflect a broad clinical phenotype ranging from diabetic ketoacidosis to mild non-insulin-requiring diabetes, also known as latent autoimmune diabetes of the adult (LADA). This latter phenotype is the most prevalent form of adult-onset autoimmune dia...

  13. Academy of Nutrition and Dietetics: standards of practice and standards of professional performance for registered dietitian nutritionists (competent, proficient, and expert) in adult weight management.

    Science.gov (United States)

    Jortberg, Bonnie; Myers, Eileen; Gigliotti, Linda; Ivens, Barbara J; Lebre, Monica; Burke March, Susan; Nogueira, Isadora; Nwankwo, Robin; Parkinson, Meredith R; Paulsen, Barbara; Turner, Tonya

    2015-04-01

    Weight management encompasses the inter-relationship of nutrition, physical activity, and health behavior change. Nutrition is key for the prevention and treatment of obesity and chronic disease and maintenance of overall health. Thus, the Weight Management Dietetic Practice Group, with guidance from the Academy of Nutrition and Dietetics Quality Management Committee, has developed Standards of Practice and Standards of Professional Performance for Registered Dietitian Nutritionists (RDNs) in Adult Weight Management as a resource for RDNs working in weight management. This document allows RDNs to assess their current skill levels and to identify areas for further professional development in this expanding practice area. This document describes the current standards for weight management practice for RDNs. The Standards of Practice represent the four steps in the Nutrition Care Process as applied to the care of patients/clients. The Standards of Professional Performance consist of six domains of professionalism: Quality in Practice, Competence and Accountability, Provision of Services, Application of Research, Communication and Application of Knowledge, and Utilization and Management of Resources. Within each standard, specific indicators provide measurable action statements that illustrate how the standard can be applied to practice. The indicators describe three skill levels (competent, proficient, and expert) for RDNs working in weight management. The Standards of Practice and Standards of Professional Performance are complementary resources for the Registered Dietitian Nutritionist in weight management.

  14. Standard practice for characterization of coatings using conformable Eddy-Current sensors without coating reference standards

    CERN Document Server

    American Society for Testing and Materials. Philadelphia

    2011-01-01

    1.1 This practice covers the use of conformable eddy-current sensors for nondestructive characterization of coatings without standardization on coated reference parts. It includes the following: (1) thickness measurement of a conductive coating on a conductive substrate, (2) detection and characterization of local regions of increased porosity of a conductive coating, and (3) measurement of thickness for nonconductive coatings on a conductive substrate or on a conductive coating. This practice includes only nonmagnetic coatings on either magnetic (μ ≠ μ0) or nonmagnetic (μ = μ0) substrates. This practice can also be used to measure the effective thickness of a process-affected zone (for example, shot peened layer for aluminum alloys, alpha case for titanium alloys). For specific types of coated parts, the user may need a more specific procedure tailored to a specific application.

  15. Determination and comparison of computed tomography quantities in standard beams using standard adult and pediatric phantoms

    Energy Technology Data Exchange (ETDEWEB)

    Martins, Elaine Wirney; Potiens, Maria da Penha A., E-mail: ewmartins@ipen.br, E-mail: mppalbu@ipen.br [Instituto de Pesquisas Energeticas e Nucleares (IPEN/CNEN-SP), Sao Paulo, SP (Brazil)

    2013-07-01

    The computed tomography (CT) is a segment of diagnostic radiology that uses higher radiation dose comparing to others fields of conventional radiology. In 2011, for decreasing the uncertainty in the diagnostic radiology beams dosimetry, the International Atomic Energy Agency (IAEA) published an implementation on the Technical Reports Series no. 457 from 2007, which is a code of practice recommending procedures for calibration and dosimetry in diagnostic radiology field. The objective of this study was to compare CT measurements on standards beams using adult and pediatric phantoms. The same procedure was used for two types of phantoms. Measurements were performed on the surface of the phantoms obtaining values of entrance surface air kerma (K{sub e}). Measurements were taken from 100 to 150 kV (RQT 8, 9 and RQT 10), with the center of the simulators positioned at a distance of 100 cm from the focal spot. The values for the CT quantities air kerma index (in free air, C{sub K}, and in phantom, C{sub PMMA,C} / C{sub PMMA,P}) and air kerma length product (P{sub KA}) were found. The results were significant and the largest difference between the two phantoms was found for the radiation quality RQT 10. (author)

  16. Technical standardization of oil well abandonment: a review of current standards and technologies

    Energy Technology Data Exchange (ETDEWEB)

    Suzart, J. Walter P.; Pessoa, Laudemar; Paiva, Maria [Halliburton Energy Services (HES), Duncan, OK (United States)

    2008-07-01

    The objective of this study is to provide a new methodology for well abandonment. This practice is becoming more and more important because of the increasing number of production fields being abandoned. We strongly recommend a study of cement slurries properties for specific use in temporary and permanent abandonment plugs based on the estimation of the cement slurry hardened when placed in the well. By using specific additives, it is possible to achieve very stable slurries. For example, when permeability is reduced, formation fluid migration can be blocked and chemical reactions between the fluid and the slurry may be inhibited. With this objective, we present a laboratory investigation model and an example of slurry testing recommendation. During the abandonment operation, all records of the well characteristics should be maintained to include the reason for the abandonment, and location of fresh water, brine, and hydrocarbon zones that may exist. This documentation will also allow the analysis of solutions for the problems that originally caused the abandonment of the well. This data could be important for future use by environmental protection commissions to reopen or to drill an adjacent well. Given the high price of oil, it may now be economically feasible to reopen the well, if the reason for abandonment was low productivity. This way, a critical analysis of the current conditions of well and field abandonment in the country is presented. Based on this information, a review of the current standards is suggested. (author)

  17. Predictors of young adults' representations of and behavior in their current romantic relationship: prospective tests of the prototype hypothesis.

    Science.gov (United States)

    Roisman, Glenn I; Collins, W Andrew; Sroufe, L Alan; Egeland, Byron

    2005-06-01

    Although attachment theory suggests that childhood experiences with caregivers serve as a prototype for adult love relationships, few explicit tests of this hypothesis exist in the literature. Drawing on data from a longitudinal cohort followed from birth to young adulthood, this paper examined correlates and antecedents of young adults' representations of and behavior in their current romantic relationship. Young adults who experienced a secure relationship with their primary caregiver in infancy as assessed in the Strange Situation were more likely to (a) produce coherent discourse regarding their current romantic partnership in the context of the Current Relationship Interview (CRI) and (b) have a higher quality romantic relationship as observed in standard conflict and collaboration tasks. Infant security accounted for variation in CRI security above and beyond the observed quality of participants' current romantic relationship. In contrast, the association between infant and romantic security was partially mediated by individuals' self-reports about their romantic experiences, suggesting that one plausible mechanism by which early experiences with caregivers shape young adults' representations of their attachments with romantic partners is through adults' expectations for and perceptions of love relationships. PMID:16096189

  18. Current cigarette smoking among adults - United States, 2005-2014.

    Science.gov (United States)

    Jamal, Ahmed; Homa, David M; O'Connor, Erin; Babb, Stephen D; Caraballo, Ralph S; Singh, Tushar; Hu, S Sean; King, Brian A

    2015-11-13

    Tobacco smoking is the leading cause of preventable disease and death in the United States, resulting in approximately 480,000 premature deaths and more than $300 billion in direct health care expenditures and productivity losses each year (1). To assess progress toward achieving the Healthy People 2020 objective of reducing the percentage of U.S. adults who smoke cigarettes to ≤12.0%,* CDC assessed the most recent national estimates of smoking prevalence among adults aged ≥18 years using data from the 2014 National Health Interview Survey (NHIS). The percentage of U.S. adults who smoke cigarettes declined from 20.9% in 2005 to 16.8% in 2014. Among daily cigarette smokers, declines were observed in the percentage who smoked 20–29 cigarettes per day (from 34.9% to 27.4%) or ≥30 cigarettes per day (from 12.7% to 6.9%). In 2014, prevalence of cigarette smoking was higher among males, adults aged 25–44 years, multiracial persons and American Indian/Alaska Natives, persons who have a General Education Development certificate, live below the federal poverty level, live in the Midwest, are insured through Medicaid or are uninsured, have a disability or limitation, or are lesbian, gay, or bisexual. Proven population-based interventions, including tobacco price increases, comprehensive smoke-free laws, high impact mass media campaigns, and barrier-free access to quitting assistance, are critical to reduce cigarette smoking and smoking-related disease and death among U.S. adults. PMID:26562061

  19. Career Development and Occupational Studies: A Supplement to the Adult Education Resource Guide and Learning Standards.

    Science.gov (United States)

    Peavey, Kay S.; Krieger, Alan

    This publication focuses on New York's learning standards for career development and occupational studies (CDOS) in adult education: career development, integrated learning, universal foundation skills, and career majors. A section on the adult learner provides information on engaging learners to increase motivation. The next section focuses on…

  20. Current issues on a standard for surrogate pregnancy procedures.

    Science.gov (United States)

    Ha, Jung-Ok

    2012-12-01

    While Korea does not have any legal statement on surrogacy, treatments are carried out in practice. As a result, every Institutional Review Board (IRB) of each fertility clinic faces an ethical predicament in reviewing each case. There is a need to arrange the institutions' own standards of surrogate pregnancy procedures before the establishment of national or professional regulation. This article examines the legal, social, and medical issues of surrogacy to help IRBs to judge their cases. PMID:23346523

  1. Current Trends in Adult Degree Programs: How Public Universities Respond to the Needs of Adult Learners

    Science.gov (United States)

    Gast, Angela

    2013-01-01

    Although many adult students turn to online degree programs due to their flexibility and convenience, a majority of prospective adult learners prefer to take classes on traditional brick-and-mortar campuses. This chapter examines how public research universities create pathways to degree attainment and boost degree completion rates among adult…

  2. Current Standards in the Management of Cerebral Metastases

    Directory of Open Access Journals (Sweden)

    Pablo Goetz

    2012-01-01

    Full Text Available The last 30 years have seen major changes in attitude toward patients with cerebral metastases. This paper aims to outline the major landmarks in this transition and the therapeutic strategies currently used. The controversies surrounding control of brain disease are discussed, and two emerging management trends are reviewed: tumor bed radiosurgery and salvage radiation.

  3. Current toxicological information as the basis for sulfur oxide standards.

    OpenAIRE

    Mehlman, M A

    1983-01-01

    The ambient air quality standard established in 1973 is 0.03 ppm annual average for sulfur dioxide and 0.075 mg/m3 for particulates. It is now generally believed that the toxicity of sulfur oxides in ambient air is significantly influenced by the coincident presence of particulates. Inhalation of 1 ppm of sulfur dioxide for 2 hr may produce alterations in pulmonary ventilatory function, both in normal and asthmatic subjects. Effects obtained at 0.5 ppm of sulfur dioxide are controversial and ...

  4. A New International Standard for "Actions from Waves and Currents on Coastal Structures"

    DEFF Research Database (Denmark)

    Tørum, Alf; Burcharth, Hans F.; Goda, Yoshimi;

    2007-01-01

    The International Organization for Standardization (ISO) is going to issue a new standard concerning "Actions from Waves and Currents on Coastal Structures," which becomes the first international standard in coastal engineering. It is composed of a normative part (29 pages), an informative part (80...... standard on coastal engineering practice....

  5. [Current model of breakfast for different age groups: children, a adolescents and adults].

    Science.gov (United States)

    Núñez, C; Cuadrado, C; Carbajal, A; Moreiras, O

    1998-01-01

    The objective of the present work is to assess the current breakfast model in different age groups: children between the ages of 6 and 12 years (n = 54); adolescents between the ages of 13 and 17 years (n = 174); and adults, older than 18 years of age (n = 252). For this a questionnaire has been designed that follows the standards of that used for a similar study by our team in 1984 on a sample of 1350 individuals. The modified and amplified questionnaire included open and closed questions about: the omission of breakfast and its causes, foods that are a part of breakfast, the most frequent types and the variations, the role of the second breakfast, the number of fasting hours since dinner, the time spent of breakfast, and the subjective opinion regarding the importance or not of having breakfast. 98.95% answer yes to the question do you have breakfast, but only 9% eats a nutritionally correct breakfast, one defined as that breakfast that supplies 20% of the total energy and includes foods from at least four different groups. All the children included some form of milk product in their breakfast. The adolescents consumed the lowest proportion of cereals (19.4%) and the highest proportion of pastries (24.2%). The percentage of adults who drink coffee with milk (57%) and sugar (37.7%) is significantly higher than that it the other two groups. Bread (37.7%), pastries (28.3%) and cookies (26.1%) are the solid foods eaten most by the adults. The children spend the longest time on breakfast. 35.9% of the sample varies their breakfast, 43.1% never does, and 21% does so sometimes. The average time elapsed between dinner and breakfast is 10.5 +/- 1.2 hours. It is advisable to have a more nutritionally balanced breakfast, including different foods from at least four groups, and including a greater variety in the menus. PMID:9780752

  6. Strengths and Limitations of Current Adult Nomograms for the Aorta Obtained by Noninvasive Cardiovascular Imaging.

    Science.gov (United States)

    Cantinotti, Massimiliano; Giordano, Raffaele; Clemente, Alberto; Assanta, Nadia; Murzi, Michele; Murzi, Bruno; Crocetti, Maura; Marotta, Marco; Scalese, Marco; Kutty, Shelby; Iervasi, Giorgio

    2016-07-01

    Normalized measurements for the evaluation of aortic disease severity are preferred to the adoption of generic cutoff values. The purpose of this review is to evaluate the strengths and limitations of currently available aortic nomograms by echocardiography, computed tomography (CT), and magnetic resonance imaging (MRI). A literature search was conducted accessing the National Library of Medicine using the keywords normal values, aorta, echocardiography, CT, and MRI. Addition of these keywords further refined the results: reference values, nomograms, aortic arch, and adults. Thirty studies were included in the final analysis. Despite the strengths noted in the recent investigations, multiple methodological and numerical limitations emerged. The numerical limitations included sample size limitation in most of the studies (only few investigations consisted of >800 subjects and many had 70-300), lack of aortic arch measurements, and paucity of data for non-Caucasian subjects. Methodological limitations consisted of lack of standardization in measurements (systole vs. diastole, internal vs. external border, axial vs. orthogonal planes), heterogeneity and data normalization issues (various age intervals used, body size often not evaluated, data expressed as observed values rather than estimated values by z-score), and study design issues. The designs were mostly retrospective with poorly defined inclusion and exclusion criteria. The nomograms presented range of normality with significant differences, but also with some reproducible pattern. Despite recent advances, multiple methodological or numerical limitations exist in adult nomograms for the aorta. Comprehensive nomograms of aortic dimensions at multiple levels including the aortic arch for different imaging techniques, involving a wide sample size, and using standardized methodology for measurements and data normalization are warranted. The availability of robust nomograms may encourage the use of personalized

  7. 3D standard brain of the red flour beetle Tribolium castaneum: a tool to study metamorphic development and adult plasticity

    Directory of Open Access Journals (Sweden)

    David Dreyer

    2010-03-01

    Full Text Available The red flour beetle Tribolium castaneum is emerging as a further standard insect model beside Drosophila. Its genome is fully sequenced and it is susceptible for genetic manipulations including RNA-interference. We use this beetle to study adult brain development and plasticity primarily with respect to the olfactory system. In the current study, we provide 3D standard brain atlases of freshly eclosed adult female and male beetles (A0. The atlases include eight paired and three unpaired neuropils including antennal lobes, optic lobe neuropils, mushroom body calyces and pedunculi, and central complex. For each of the two standard brains, we averaged brain areas of 20 individual brains. Additionally, we characterized eight selected olfactory glomeruli from 10 A0 female and male beetles respectively, which we could unequivocally recognize from individual to individual owing to their size and typical position in the antennal lobes. In summary, comparison of the averaged neuropil volumes revealed no sexual dimorphism in any of the reconstructed neuropils in A0 Tribolium brains. Both, the female and male 3D standard brain are also used for interspecies comparisons, and, very importantly, will serve as future volumetric references after genetical manipulation especially regarding metamorphic development and adult plasticity.

  8. International Financial Reporting Standard 5 - Non-Current Assets Held for Sale and Discontinued Operations

    OpenAIRE

    Luka Crnkovic; Ivo Mijoc; Drazen Cucic

    2007-01-01

    International Financial Reporting Standard 5 has the working title Non-current assets held for sale and discontinued operations. This fi nancial reporting standard also represents a new group of standards along with the previous four, including existing International Accounting Standard, regardless if it concerns existing or revised standards, as a wish for further coordination of accounting regulations on world level. This idea is a concretisation of the wishes of International Accounting St...

  9. Certificate of Analysis, Standard Reference Material® 1849, Infant/Adult Nutritional Formula

    Science.gov (United States)

    Standard Reference material (SRM) 1849 is intended primarily for validation of methods for determining proximates, fatty acids, vitamins, elements and nucleotides in infant and adult nutritional formulas and similar materials. This SRM can also be used for quality assurance when assigning values to ...

  10. Childhood socioeconomic deprivation, but not current mood, is associated with behavioural disinhibition in adults

    Directory of Open Access Journals (Sweden)

    Tünde Paál

    2015-05-01

    Full Text Available There is evidence to suggest that impulsivity is predicted by socioeconomic background, with people from more deprived backgrounds tending to be more impulsive, and by current mood, with poorer mood associated with greater impulsivity. However, impulsivity is not a unitary construct, and previous research in this area has focused on measures of ‘waiting’ impulsivity rather than behavioural disinhibition. We administered a standard measure of behavioural disinhibition, the stop-signal task, to 58 adult participants from a community sample. We had measured socioeconomic background using participant postcode at age 16, and assigned participants to receive either a neutral or a negative mood induction. We found no effects of mood on behavioural disinhibition, but we found a significant effect of socioeconomic background. Participants who had lived in more deprived postcodes at age 16 showed longer stop-signal reaction times, and hence greater behavioural disinhibition. The pattern was independent of participant age and overall reaction time. Though caution is required inferring causality from correlation, it is possible that that experiencing socioeconomic deprivation in childhood and adolescence may lead to greater behavioural disinhibition in adulthood.

  11. Adults with poor reading skills: How lexical knowledge interacts with scores on standardized reading comprehension tests.

    Science.gov (United States)

    McKoon, Gail; Ratcliff, Roger

    2016-01-01

    Millions of adults in the United States lack the necessary literacy skills for most living wage jobs. For students from adult learning classes, we used a lexical decision task to measure their knowledge of words and we used a decision-making model (Ratcliff's, 1978, diffusion model) to abstract the mechanisms underlying their performance from their RTs and accuracy. We also collected scores for each participant on standardized IQ tests and standardized reading tests used commonly in the education literature. We found significant correlations between the model's estimates of the strengths with which words are represented in memory and scores for some of the standardized tests but not others. The findings point to the feasibility and utility of combining a test of word knowledge, lexical decision, that is well-established in psycholinguistic research, a decision-making model that supplies information about underlying mechanisms, and standardized tests. The goal for future research is to use this combination of approaches to understand better how basic processes relate to standardized tests with the eventual aim of understanding what these tests are measuring and what the specific difficulties are for individual, low-literacy adults. PMID:26550803

  12. Insulin resistance modifies the association between obesity and current asthma in adults.

    Science.gov (United States)

    Cardet, Juan Carlos; Ash, Samuel; Kusa, Tope; Camargo, Carlos A; Israel, Elliot

    2016-08-01

    Insulin resistance potentiates the association between obesity and childhood asthma, but this relationship appears inconsistent in relatively small studies of adults. We investigated effect modification in adults using the National Health and Nutrition Examination Survey 2003-2012, a large, nationally representative database.Insulin resistance and a history of physician-diagnosed current asthma were obtained from 12 421 adults, ages 18-85 years. We used logistic regression to determine associations between obesity and current asthma, adjusting for age, sex, race/ethnicity, poverty income ratio and smoking status. An interaction term evaluated effect modification by insulin resistance of the obesity-asthma association.As expected, obesity was positively associated with current asthma. Insulin resistance modified this association, with obesity measured as body mass index, waist circumference or waist-to-height ratio. The relationship between obesity and current asthma was stronger with increasing insulin resistance tertiles (OR 2.05, 95% CI 2.76-3.00; p-value for interaction 0.03). This association was robust to adjustments for other components of the metabolic syndrome (hypertriglyceridaemia, hypertension, hyperglycaemia and systemic inflammation). None of these components were themselves effect modifiers of the obesity-asthma association.In this large, nationally representative sample, insulin resistance modified the association between obesity and current asthma in adults. Targeting insulin resistance may represent a novel therapeutic strategy for obese patients with asthma. PMID:27103388

  13. Current-Voltage Relationship for Late Na(+) Current in Adult Rat Ventricular Myocytes.

    Science.gov (United States)

    Clark, R B; Giles, W R

    2016-01-01

    It is now well established that the slowly inactivating component of the Na(+) current (INa-L) in the mammalian heart is a significant regulator of the action potential waveform. This insight has led to detailed studies of the role of INa-L in a number of important and challenging pathophysiological settings. These include genetically based ventricular arrhythmias (LQT 1, 2, and 3), ventricular arrhythmias arising from progressive cardiomyopathies (including diabetic), and proarrhythmic abnormalities that develop during local or global ventricular ischemia. Inhibition of INa-L may also be a useful strategy for management of atrial flutter and fibrillation. Many important biophysical parameters that characterize INa-L have been identified; and INa-L as an antiarrhythmia drug target has been studied extensively. However, relatively little information is available regarding (1) the ion transfer or current-voltage relationship for INa-L or (2) the time course of its reactivation at membrane potentials similar to the resting or diastolic membrane potential in mammalian ventricle. This chapter is based on our preliminary findings concerning these two very important physiological/biophysical descriptors for INa-L. Our results were obtained using whole-cell voltage clamp methods applied to enzymatically isolated rat ventricular myocytes. A chemical agent, BDF 9148, which was once considered to be a drug candidate in the Na(+)-dependent inotropic agent category has been used to markedly enhance INa-L current. BDF acts in a potent, selective, and reversible fashion. These BDF 9148 effects are compared and contrasted with the prototypical activator of INa-L, a sea anemone toxin, ATX II. PMID:27586292

  14. Adult Sexual Experiences as a Mediator Between Child Abuse and Current Secretory Immunoglobulin A Levels.

    Science.gov (United States)

    Waldron, Jonathan C; Scarpa, Angela; Kim-Spoon, Jungmeen; Coe, Christopher L

    2016-03-01

    The current study investigated whether a history of child abuse is a predictor of adult immune status, with unwanted adult sexual experiences as a proximal mediator. Participants included 89 young adult women (M(age) = 19.24) who were classified as having experienced no child abuse, child physical abuse, or child sexual abuse, based upon self-reported victimization history before 14 years of age. Participants also reported on unwanted sexual experiences in young adulthood and provided four saliva samples, which were collected over two consecutive days to determine secretory immunoglobulin A (sIgA). Age and negative life events were considered as covariates. The results indicated that adult sexual victimization partially mediated the relationship between child abuse (physical and sexual) and sIgA. Specifically, child abuse experiences predicted more adult sexual victimization experiences, which in turn predicted lower sIgA levels. These findings support long-term health effects of victimization, and suggest that the influence of child abuse on sIgA may be perpetuated through adult victimization. Prevention efforts should aim to empower child maltreatment survivors with skills to prevent adult re-victimization. By thwarting future unwanted sexual experiences in adulthood, individuals will be better protected from the health impairments associated with early abuse experiences.

  15. The Commission of Professors of Adult Education 2008 "Standards" as Evidenced in the Curricula of Doctoral Education in North America

    Science.gov (United States)

    Sonstrom, Wendy Jean; Rachal, John R.; Mohn, Richard S.

    2013-01-01

    In 2008, the Commission of Professors of Adult Education approved and published "Standards for Graduate Programs in Adult Education," an update of the 1986 "Standards." Using the program websites of the 37 North American programs ascertained to have doctoral programs in the field, this study evaluated all programs' course descriptions for…

  16. Critical analysis of the current treatment guidelines for complex PTSD in adults

    NARCIS (Netherlands)

    Jongh, A. de; Resick, P.A.; Zoellner, L.A.; Minnen, A. van; Lee, C.W.; Monson, C.M.; Foa, E.B.; Wheeler, K.; Broeke, E. ten; Feeny, N.; Rauch, S.A.M.; Chard, K.M.; Mueser, K.T.; Sloan, D.M.; Gaag, M. van der; Rothbaum, B.O.; Neuner, F.; Roos, C.J.A.M. de; Hehenkamp, L.M.J.; Rosner, R.; Bicanic, I.A.E.

    2016-01-01

    According to current treatment guidelines for Complex PTSD (cPTSD), psychotherapy for adults with cPTSD should start with a "stabilization phase". This phase, focusing on teaching self-regulation strategies, was designed to ensure that an individual would be better able to tolerate trauma-focused tr

  17. Current Status of International Airborne Platform Data and Instrument Interface Standards

    Science.gov (United States)

    Freer, Matt; Webster, Chris; Freundinger, Larry

    2016-06-01

    Commission I of the International Society for Photogrammetric and Remote Sensing formed working group I/1 for the purpose of standardizing airborne platform interfaces. The primary mission of this working group is to promote the standardization of instrument interfaces, data formats, and supporting infrastructures; and to facilitate more efficient, flexible, and cost-effective international science flight operations. Within WGI/1 are a number of focused subgroups. This paper addresses the efforts of some of these subgroups having interdependent and overlapping interests; including the development of standard software interfaces for sensors, standardized approaches to management of information over potentially intermittent wireless data links, the development of standardized processing algorithms, and data archival format standards. The data in this report reflect the outcome of work-to-date in the current subgroups.

  18. Strategies of bringing drug product marketing applications to meet current regulatory standards.

    Science.gov (United States)

    Wu, Yan; Freed, Anita; Lavrich, David; Raghavachari, Ramesh; Huynh-Ba, Kim; Shah, Ketan; Alasandro, Mark

    2015-08-01

    In the past decade, many guidance documents have been issued through collaboration of global organizations and regulatory authorities. Most of these are applicable to new products, but there is a risk that currently marketed products will not meet the new compliance standards during audits and inspections while companies continue to make changes through the product life cycle for continuous improvement or market demands. This discussion presents different strategies to bringing drug product marketing applications to meet current and emerging standards. It also discusses stability and method designs to meet process validation and global development efforts.

  19. Strategies of bringing drug product marketing applications to meet current regulatory standards.

    Science.gov (United States)

    Wu, Yan; Freed, Anita; Lavrich, David; Raghavachari, Ramesh; Huynh-Ba, Kim; Shah, Ketan; Alasandro, Mark

    2015-08-01

    In the past decade, many guidance documents have been issued through collaboration of global organizations and regulatory authorities. Most of these are applicable to new products, but there is a risk that currently marketed products will not meet the new compliance standards during audits and inspections while companies continue to make changes through the product life cycle for continuous improvement or market demands. This discussion presents different strategies to bringing drug product marketing applications to meet current and emerging standards. It also discusses stability and method designs to meet process validation and global development efforts. PMID:26024722

  20. CRITICAL ANALYSIS OF THE CURRENT TREATMENT GUIDELINES FOR COMPLEX PTSD IN ADULTS.

    Science.gov (United States)

    De Jongh, Ad; Resick, Patricia A; Zoellner, Lori A; van Minnen, Agnes; Lee, Christopher W; Monson, Candice M; Foa, Edna B; Wheeler, Kathleen; Broeke, Erik Ten; Feeny, Norah; Rauch, Sheila A M; Chard, Kathleen M; Mueser, Kim T; Sloan, Denise M; van der Gaag, Mark; Rothbaum, Barbara Olasov; Neuner, Frank; de Roos, Carlijn; Hehenkamp, Lieve M J; Rosner, Rita; Bicanic, Iva A E

    2016-05-01

    According to current treatment guidelines for Complex PTSD (cPTSD), psychotherapy for adults with cPTSD should start with a "stabilization phase." This phase, focusing on teaching self-regulation strategies, was designed to ensure that an individual would be better able to tolerate trauma-focused treatment. The purpose of this paper is to critically evaluate the research underlying these treatment guidelines for cPTSD, and to specifically address the question as to whether a phase-based approach is needed. As reviewed in this paper, the research supporting the need for phase-based treatment for individuals with cPTSD is methodologically limited. Further, there is no rigorous research to support the views that: (1) a phase-based approach is necessary for positive treatment outcomes for adults with cPTSD, (2) front-line trauma-focused treatments have unacceptable risks or that adults with cPTSD do not respond to them, and (3) adults with cPTSD profit significantly more from trauma-focused treatments when preceded by a stabilization phase. The current treatment guidelines for cPTSD may therefore be too conservative, risking that patients are denied or delayed in receiving conventional evidence-based treatments from which they might profit. PMID:26840244

  1. Adult human neural stem cell therapeutics: Current developmental status and prospect

    OpenAIRE

    Nam, Hyun; Lee, Kee-Hang; Nam, Do-Hyun; Joo, Kyeung Min

    2015-01-01

    Over the past two decades, regenerative therapies using stem cell technologies have been developed for various neurological diseases. Although stem cell therapy is an attractive option to reverse neural tissue damage and to recover neurological deficits, it is still under development so as not to show significant treatment effects in clinical settings. In this review, we discuss the scientific and clinical basics of adult neural stem cells (aNSCs), and their current developmental status as ce...

  2. Taper Preparation Variability Compared to Current Taper Standards Using Computed Tomography

    OpenAIRE

    Richard Gergi; Joe Abou Rjeily; Nada Osta; Joseph Sader; Alfred Naaman

    2012-01-01

    Introduction. The purpose of this study was to compare the taper variation in root canal preparations among Twisted Files and PathFiles-ProTaper .08 tapered rotary files to current standards. Methods. 60 root canals with severe angle of curvature (between 25∘ and 35∘) and short radius (

  3. Difference of Sodium Currents between Pediatric and Adult Human Atrial Myocytes: Evidence for Developmental Changes of Sodium Channels

    Directory of Open Access Journals (Sweden)

    Benzhi Cai, Xiaoqin Mu, Dongmei Gong, Shulin Jiang, Jianping Li, Qingxin Meng, Yunlong Bai, Yanju Liu, Xinyue Wang, Xueying Tan, Baofeng Yang, Yanjie Lu

    2011-01-01

    Full Text Available Voltage-gated calcium currents and potassium currents were shown to undergo developmental changes in postnatal human and animal cardiomocytes. However, so far, there is no evidence whether sodium currents also presented the developmental changes in postnatal human atrial cells. The aim of this study was to observe age-related changes of sodium currents between pediatric and adult atrial myocytes. Human atrial myocytes were acutely isolated and the whole-cell patch clamp technique was used to record sodium currents isolated from pediatric and adult atrial cardiomocytes. The peak amplitude of sodium currents recorded in adult atrial cells was significantly larger than that in pediatric atrial myocytes. However, there was no significant difference of the activation voltage for peak sodium currents between two kinds of atrial myocytes. The time constants for the activation and inactivation of sodium currents were smaller in adult atria than pediatric atria. The further study revealed that the voltage-dependent inactivation of sodium currents were more slow in adult atrial cardiomyocytes than pediatric atrial cells. A significant difference was also observed in the recovery process of sodium channel from inactivation. In summary, a few significant differences were demonstrated in sodium currents characteristics between pediatric and adult atrial myocytes, which indicates that sodium currents in human atria also undergo developmental changes.

  4. Low dose nicotine self-administration is reduced in adult male rats naïve to high doses of nicotine: Implications for nicotine product standards

    OpenAIRE

    Smith, Tracy T.; Schassburger, Rachel L.; Buffalari, Deanne M.; Sved, Alan F.; Donny, Eric C.

    2014-01-01

    Product standards that greatly reduce the content of nicotine within cigarettes may result in improved public health. The present study used an animal model to investigate whether individuals who start smoking following implementation of regulation may be affected differently from current smokers who form the basis of most clinical studies. One group of adult male rats (n=14/group) acquired nicotine self-administration at a high nicotine dose (60 μg/kg/infusion) before experiencing a reductio...

  5. Factors influencing adult physical health after controlling for current health conditions: evidence from a british cohort.

    Directory of Open Access Journals (Sweden)

    Helen Cheng

    Full Text Available This study explored a longitudinal data set of 6875 British adults examining the effects of parental social status (measured at birth, cognitive ability (at age 11 yrs, personality traits, education and occupational attainment on physical health and functioning (all measured at age 50 yrs, after taking account of current health conditions (number of illness. Correlation analysis showed that parental social class, childhood cognitive ability, education and occupation, and two personality traits (Emotional Stability/Neuroticism, and Conscientiousness were all significantly associated with adult physical health variables. Structural equation modelling showed that health conditions and personality traits were significantly, and inversely, associated with physical health (indicated by good daily physical functioning, relative absence of pain, perceived health, and low level of limitations at work due to physical health. Parental social status, childhood intelligence, educational and occupational attainment were all modestly, but significantly and directly, associated with adult physical health. The effect of childhood intelligence on adult physical health was, in part, mediated through Emotional Stability and Conscientiousness. After controlling for health conditions Emotional Stability was the strongest predictor of physical health. Implications and limitations are discussed.

  6. Standard Operating Procedures for PET/CT: A Practical Approach for Use in Adult Oncology

    International Nuclear Information System (INIS)

    of operating procedures for FDG-PET/CT imaging in adult oncology patients. The text is based on consensus and agreement among the authors, following a systematic approach of relying on personal experience and the available scientific evidence on all the subjects included. Due to the evolving nature of PET/CT imaging, which is a rapidly growing technology, this publication will undoubtedly need to be updated on a regular basis. It may well be that each PET/CT centre will have to modify the recommendations provided here to suit its own particular circumstances, according to, inter alia, the type of scanner, patient population, use of intravenous contrast, availability of FDG, professional staff experience, local regulations and preferences of referring physicians. The information provided here is felt to be important in the light of the growing need to standardize and optimize the way PET/CT scans are performed, not only to enable trials using FDG-PET/CT in different institutions to be compared and correlated, but also to allow for more accurate comparisons of scans performed on the same patient at different points in time at a single institution. This is important when assessing the response to cancer therapy, and especially so when this evaluation is performed early and after using novel targeted treatments that very often only produce changes in metabolic activity and not in lesion/tumour size. This is the reason why strictly following a correct imaging protocol is crucial. The reliability of the PET/CT imaging information in cancer patients depends on trustworthy and consistently applied protocols. This issue has current relevance in drug discovery and development, where PET/CT imaging with FDG and other radiotracers is viewed by the pharmaceutical industry as potentially useful for shortening the process of clinical validation of new drugs

  7. Modeling of tube current modulation methods in computed tomography dose calculations for adult and pregnant patients

    International Nuclear Information System (INIS)

    The comparatively high dose and increasing frequency of computed tomography (CT) examinations have spurred the development of techniques for reducing radiation dose to imaging patients. Among these is the application of tube current modulation (TCM), which can be applied either longitudinally along the body or rotationally along the body, or both. Existing computational models for calculating dose from CT examinations do not include TCM techniques. Dose calculations using Monte Carlo methods have been previously prepared for constant-current rotational exposures at various positions along the body and for the principle exposure projections for several sets of computational phantoms, including adult male and female and pregnant patients. Dose calculations from CT scans with TCM are prepared by appropriately weighting the existing dose data. Longitudinal TCM doses can be obtained by weighting the dose at the z-axis scan position by the relative tube current at that position. Rotational TCM doses are weighted using the relative organ doses from the principle projections as a function of the current at the rotational angle. Significant dose reductions of 15% to 25% to fetal tissues are found from simulations of longitudinal TCM schemes to pregnant patients of different gestational ages. Weighting factors for each organ in rotational TCM schemes applied to adult male and female patients have also been found. As the application of TCM techniques becomes more prevalent, the need for including TCM in CT dose estimates will necessarily increase. (author)

  8. Electric current in flares ribbons: from the standard model in 3D to observations

    CERN Document Server

    Janvier, Miho; Bommier, V; Schmieder, B; Démoulin, P; Pariat, E

    2014-01-01

    The paper presents for the first time a quantification of the photospheric electric current ribbon evolutions during an eruptive flare, accurately predicted by the standard 3D flare model. The standard flare model in 3D has been developed with the MHD code OHM, which models the evolution of an unstable flux rope. Through a series of paper, the model has been successful in explaining observational characteristics of eruptive flares, as well as the intrinsic 3D reconnection mechanism. Such a model also explains the increase of the photospheric currents as a consequence of the evolution of the coronal current layer where reconnection takes place. The photospheric footprints of the 3D current layer reveal a ribbon shape structure. In the present paper, the evolution of the current density is analyzed for the X-class flare that occurred on 15/02/2011 in AR 11158. We first describe the structural evolution of the high vertical current density regions derived with the UNNOFIT inversion code from magnetograms (HMI, e...

  9. Training in clinical forensic medicine in the UK--perceptions of current regulatory standards.

    Science.gov (United States)

    Stark, Margaret M; Norfolk, Guy A

    2011-08-01

    As clinical forensic medicine (CFM) is not currently recognised as a speciality in the UK there are no nationally agreed mandatory standards for training forensic physicians in either general forensic (GFM) or sexual offence medicine (SOM). The General Medical Council (GMC), the medical regulator in the UK, has issued clear standards for training in all specialities recommending that "trainees must be supported to acquire the necessary skills and experience through induction, effective educational supervision, an appropriate workload and time to learn". In order to evaluate the current situation in the field of clinical forensic medicine, doctors who have recently (within the last two years) started working in the field "trainees" (n = 38), and trainers (n = 61) with responsibility for clinical and educational supervision of new trainees, were surveyed by questionnaire to gather their perceptions of how the relevant GMC standards are being met in initial on-the-job training. Telephone interviews were performed with eleven doctors working as clinical or medical directors to determine their views. It is clear that currently the quality of training in CFM is sub-standard and inconsistent and that the published standards, as to the minimum requirement for training that must be met by post-graduate medical and training providers at all levels, are not being met. The Faculty of Forensic and Legal Medicine (FFLM) needs to set explicit minimum standards which will comply with the regulator and work to pilot credentialing for forensic physicians. A number of recommendations are made for urgent FFLM development. PMID:21771557

  10. Training in clinical forensic medicine in the UK--perceptions of current regulatory standards.

    Science.gov (United States)

    Stark, Margaret M; Norfolk, Guy A

    2011-08-01

    As clinical forensic medicine (CFM) is not currently recognised as a speciality in the UK there are no nationally agreed mandatory standards for training forensic physicians in either general forensic (GFM) or sexual offence medicine (SOM). The General Medical Council (GMC), the medical regulator in the UK, has issued clear standards for training in all specialities recommending that "trainees must be supported to acquire the necessary skills and experience through induction, effective educational supervision, an appropriate workload and time to learn". In order to evaluate the current situation in the field of clinical forensic medicine, doctors who have recently (within the last two years) started working in the field "trainees" (n = 38), and trainers (n = 61) with responsibility for clinical and educational supervision of new trainees, were surveyed by questionnaire to gather their perceptions of how the relevant GMC standards are being met in initial on-the-job training. Telephone interviews were performed with eleven doctors working as clinical or medical directors to determine their views. It is clear that currently the quality of training in CFM is sub-standard and inconsistent and that the published standards, as to the minimum requirement for training that must be met by post-graduate medical and training providers at all levels, are not being met. The Faculty of Forensic and Legal Medicine (FFLM) needs to set explicit minimum standards which will comply with the regulator and work to pilot credentialing for forensic physicians. A number of recommendations are made for urgent FFLM development.

  11. Standardization of Administered Activities in Pediatric Nuclear Medicine: A Report of the First Nuclear Medicine Global Initiative Project, Part 2-Current Standards and the Path Toward Global Standardization.

    Science.gov (United States)

    Fahey, Frederic H; Bom, Henry Hee-Seung; Chiti, Arturo; Choi, Yun Young; Huang, Gang; Lassmann, Michael; Laurin, Norman; Mut, Fernando; Nuñez-Miller, Rodolfo; O'Keeffe, Darin; Pradhan, Prasanta; Scott, Andrew M; Song, Shaoli; Soni, Nischal; Uchiyama, Mayuki; Vargas, Luis

    2016-07-01

    The Nuclear Medicine Global Initiative (NMGI) was formed in 2012 and consists of 13 international organizations with direct involvement in nuclear medicine. The underlying objectives of the NMGI are to promote human health by advancing the field of nuclear medicine and molecular imaging, encourage global collaboration in education, and harmonize procedure guidelines and other policies that ultimately lead to improvements in quality and safety in the field throughout the world. For its first project, the NMGI decided to consider the issues involved in the standardization of administered activities in pediatric nuclear medicine. It was decided to divide the final report of this project into 2 parts. Part 1 was published in this journal in the spring of 2015. This article presents part 2 of the final report. It discusses current standards for administered activities in children and adolescents that have been developed by various professional organizations. It also presents an evaluation of the current practice of pediatric nuclear medicine specifically with regard to administered activities as determined by an international survey of 313 nuclear medicine clinics and centers from 29 countries. Lastly, it provides recommendations for a path toward global standardization of the administration of radiopharmaceuticals in children. PMID:27033894

  12. Attachment among older adults: current issues and directions for future research.

    Science.gov (United States)

    Bradley, J M; Cafferty, T P

    2001-09-01

    Although John Bowlby conceptualized attachment theory as applicable across the life span, researchers have been relatively slow to examine attachment phenomena specifically among older adults. The present article reviews the extant research applying attachment theory to older populations; preliminary findings suggest that attachment issues hold particular relevance for older adults, given the increased potential for separation, loss and vulnerability associated with aging. Although many of the studies reviewed are somewhat limited methodologically, the overall pattern of results suggests that attachment patterns are associated with a variety of outcomes in later life (such as adaptation to chronic illness and caregiver burden among family members, reactions to the death of a loved one, and general well-being) in a theoretically consistent manner. The implications of and questions raised by current findings are reviewed, and directions for future research are discussed.

  13. Bioelectrical impedance analysis (BIA): a proposal for standardization of the classical method in adults

    International Nuclear Information System (INIS)

    The accuracy of BIA measurements is limited by different sources of error such as physical model, cross sectional area, ethnicity, body hydration, age and level of body fat among other variables. Equation for each population is required as they can produce overestimation when manufacturer's equations are used. The classical measurements hand to foot has shown better correlation against hydrodensitometry than foot to foot or hand to hand. However there is a lack for an accepted standard of BIA procedures. This is compounded when there is not a good report of the BIA study's methodology; hence the comparability between the results is poor and reduces the reliability of the method. Perhaps, standardization of methods would be the first step for BIA studies to move forward and subsequently improve its accuracy. Standardized procedures could also minimize the impact of these variables on studies results. The aim of this study was to propose a protocol as a checklist to standardize BIA procedures and produce comparable results from future studies performed with the classic hand-foot configuration in adults.

  14. Analysis of the Current Technical Issues on ASME Code and Standard for Nuclear Mechanical Design(2009)

    International Nuclear Information System (INIS)

    This report describes the analysis on the current revision movement related to the mechanical design issues of the U.S ASME nuclear code and standard. ASME nuclear mechanical design in this report is composed of the nuclear material, primary system, secondary system and high temperature reactor. This report includes the countermeasures based on the ASME Code meeting for current issues of each major field. KAMC(ASME Mirror Committee) of this project is willing to reflect a standpoint of the domestic nuclear industry on ASME nuclear mechanical design and play a technical bridge role for the domestic nuclear industry in ASME Codes application

  15. American Dietetic Association's Standardized Nutrition Language: Project logic model and current status.

    Science.gov (United States)

    Jenkins, Melinda; Myers, Esther; Charney, Pam; Escott-Stump, Sylvia

    2006-01-01

    Standardized terminology and digital sources of evidence are essential for evidence-based practice. Dieticians desire concise and consistent documentation of nutrition diagnoses, interventions and outcomes that will be fit for electronic health records. Building on more than 5 years of work to generate the Nutrition Care Process and Model as a road map to quality nutrition care and outcomes, and recognizing existing standardized languages serving other health professions, a task force of the American Dietetic Association (ADA) has begun to develop and disseminate standardized nutrition language. This paper will describe the group's working logic model, the Nutrition Care Process, and the current status of the nutrition language with comparisons to nursing process and terminology.

  16. Regional hyperthermia combined with chemotherapy in paediatric, adolescent and young adult patients: current and future perspectives

    International Nuclear Information System (INIS)

    Here we evaluate the current status of clinical research on regional hyperthermia (RHT) in combination with chemotherapy or radiation therapy in paediatric oncology. Data were identified in searches of MEDLINE, Current Contents, PubMed, and references from relevant articles using medical subject headings including hyperthermia, cancer, paediatric oncology, children, radiation therapy and chemotherapy. Currently, only two RHT centres exist in Europe which treat children. Clinical RHT research in paediatric oncology has as yet been limited to children with sarcomas and germ cell tumours that respond poorly to or recur after chemotherapy. RHT is a safe and effective treatment delivering local thermic effects, which may also stimulate immunological processes via heat-shock protein reactions. RHT is used chiefly in children and adolescents with sarcomas or germ cell tumours located in the abdomino-pelvic region, chest wall or extremities to improve operability or render the tumour operable. It could potentially be combined with radiation therapy in a post-operative R1 setting where more radical surgery is not possible or combined with chemotherapy instead of radiation therapy in cases where the necessary radiation dose is impossible to achieve or would have mutilating consequences. RHT might also be an option for chemotherapy intensification in the neoadjuvant first-line treatment setting for children and adolescents, as was recently reflected in the promising long-term outcome data in adults with high-risk soft tissue sarcomas (EORTC 62961/ESHO trial). The limited data available indicate that combining RHT with chemotherapy is a promising option to treat germ cell tumours and, potentially, sarcomas. RHT may also be beneficial in first-line therapy in children, adolescents and young adults. The research should focus on optimising necessary technical demands and then initiate several clinical trials incorporating RHT into interdisciplinary treatment of children

  17. Improved reading measures in adults with dyslexia following transcranial direct current stimulation treatment.

    Science.gov (United States)

    Heth, Inbahl; Lavidor, Michal

    2015-04-01

    To better understand the contribution of the dorsal system to word reading, we explored transcranial direct current stimulation (tDCS) effects when adults with developmental dyslexia received active stimulation over the visual extrastriate area MT/V5, which is dominated by magnocellular input. Stimulation was administered in 5 sessions spread over two weeks, and reading speed and accuracy as well as reading fluency were assessed before, immediately after, and a week after the end of the treatment. A control group of adults with developmental dyslexia matched for age, gender, reading level, vocabulary and block-design WAIS-III sub-tests and reading level was exposed to the same protocol but with sham stimulation. The results revealed that active, but not sham stimulation, significantly improved reading speed and fluency. This finding suggests that the dorsal stream may play a role in efficient retrieval from the orthographic input lexicon in the lexical route. It also underscores the potential of tDCS as an intervention tool for improving reading speed, at least in adults with developmental dyslexia.

  18. Standard procedures for adults in accredited sleep medicine centres in Europe

    DEFF Research Database (Denmark)

    Fischer, Jürgen; Dogas, Zoran; Bassetti, Claudio L;

    2012-01-01

    at creating standards of practice in European sleep medicine. It is also part of a broader action plan of the European Sleep Research Society, including the process of accreditation of sleep medicine centres and certification of sleep medicine experts, as well as publishing the Catalogue of Knowledge......The present paper describes standardized procedures within clinical sleep medicine. As such, it is a continuation of the previously published European guidelines for the accreditation of sleep medicine centres and European guidelines for the certification of professionals in sleep medicine, aimed...... and Skills for sleep medicine experts (physicians, non-medical health care providers, nurses and technologists), which will be a basis for the development of relevant educational curricula. In the current paper, the standard operational procedures sleep medicine centres regarding the diagnostic...

  19. Current issues with standards in the measurement and documentation of human skeletal anatomy.

    Science.gov (United States)

    Magee, Justin; McClelland, Brian; Winder, John

    2012-09-01

    Digital modeling of human anatomy has become increasingly important and relies on well-documented quantitative anatomy literature. This type of documentation is common for the spine and pelvis; however, significant issues exist due to the lack of standardization in measurement and technique. Existing literature on quantitative anatomy for the spine and pelvis of white adults (aged 18-65 years, separated into decadal categories) was reviewed from the disciplines of anatomy, manipulative therapy, anthropometrics, occupational ergonomics, biomechanics and forensic science. The data were unified into a single normative model of the sub-axial spine. Two-dimensional orthographic drawings were produced from the 590 individual measurements identified, which informed the development of a 3D digital model. A similar review of full range of motion data was conducted as a meta-analysis and the results were applied to the existing model, providing an inter-connected, articulated digital spine. During these data analysis processes several inconsistencies were observed accompanied by an evidential lack of standardization with measurement and recording of data. These have been categorized as: anatomical terminology; scaling of measurements; measurement methodology, dimension and anatomical reference positions; global coordinate systems. There is inconsistency in anatomical terminology where independent researchers use the same terms to describe different aspects of anatomy or different terms for the same anatomy. Published standards exist for measurement methods of the human body regarding spatial interaction, anthropometric databases, automotive applications, clothing industries and for computer manikins, but none exists for skeletal anatomy. Presentation of measurements often lacks formal structure in clinical publications, seldom providing geometric reference points, therefore making digital reconstruction difficult. Published quantitative data does not follow existing

  20. Looking back: the experience of first sexual intercourse and current sexual adjustment in young heterosexual adults.

    Science.gov (United States)

    Reissing, Elke D; Andruff, Heather L; Wentland, Jocelyn J

    2012-01-01

    A young person's first consensual sexual intercourse experience is often a remarkable and memorable experience. However, little systematic information exists regarding contextual factors of first intercourse, the affective salience of the experience, possible effects on sexual attitudes and beliefs, and subsequent sexual development and adjustment. This retrospective study aimed to examine these in a sample of 475 young adults. Overall, young men and women experienced intercourse for the first time around age 17, were in a committed relationship, and reported positive affective responses. Affective reactions to the first sexual intercourse experience, sexual self-efficacy, sexual aversion, and age at first intercourse affected individuals' current sexual adjustment; however, only sexual self-efficacy mediated between first intercourse and current sexual adjustment in young men and women. Older age at first intercourse was associated with less sexual self-efficacy and lower current sexual adjustment for women. This study provides initial data to suggest that the first sexual intercourse experience significantly impacts current sexual adjustment by affecting beliefs about sexual self-efficacy. PMID:21161815

  1. Including Alternative Resources in State Renewable Portfolio Standards: Current Design and Implementation Experience

    Energy Technology Data Exchange (ETDEWEB)

    Heeter, J.; Bird, L.

    2012-11-01

    Currently, 29 states, the District of Columbia, and Puerto Rico have instituted a renewable portfolio standard (RPS). An RPS sets a minimum threshold for how much renewable energy must be generated in a given year. Each state policy is unique, varying in percentage targets, timetables, and eligible resources. This paper examines state experience with implementing renewable portfolio standards that include energy efficiency, thermal resources, and non-renewable energy and explores compliance experience, costs, and how states evaluate, measure, and verify energy efficiency and convert thermal energy. It aims to gain insights from the experience of states for possible federal clean energy policy as well as to share experience and lessons for state RPS implementation.

  2. ASME nuclear codes and standards: Scope of coverage and current initiatives

    International Nuclear Information System (INIS)

    The objective of this paper is to address the broad scope of coverage of nuclear codes, standards and guides produced and administered by the American Society of Mechanical Engineers (ASME). Background information is provided regarding the evolution of the present activities. Details are provided on current initiatives intended to permit ASME to meet the needs of a changing nuclear industry on a worldwide scale. During the early years of commercial nuclear power, ASME produced a code for the construction of nuclear vessels used in the reactor coolant pressure boundary, containment and auxiliary systems. In response to industry growth, ASME Code coverage soon broadened to include rules for construction of other nuclear components, and inservice inspection of nuclear reactor coolant systems. In the years following this, the scope of ASME nuclear codes, standards and guides has been broadened significantly to include air cleaning activities for nuclear power reactors, operation and maintenance of nuclear power plants, quality assurance programs, cranes for nuclear facilities, qualification of mechanical equipment, and concrete reactor vessels and containments. ASME focuses on globalization of its codes, standards and guides by encouraging and promoting their use in the international community and by actively seeking participation of international members on its technical and supervisory committees and in accreditation activities. Details are provided on current international representation. Initiatives are underway to separate the technical requirements from administrative and enforcement requirements, to convert to hard metric units, to provide for non-U. S. materials, and to provide for translations into non-English languages. ASME activity as an accredited ISO 9000 registrar for suppliers of mechanical equipment is described. Rules are being developed for construction of containment systems for nuclear spent fuel and high-level waste transport packagings. Intensive

  3. Recommendation for modifying current cytotoxicity testing standards for biodegradable magnesium-based materials.

    Science.gov (United States)

    Wang, Jiali; Witte, Frank; Xi, Tingfei; Zheng, Yufeng; Yang, Ke; Yang, Yuansheng; Zhao, Dewei; Meng, Jian; Li, Yangde; Li, Weirong; Chan, Kaiming; Qin, Ling

    2015-07-01

    As one of the most promising medical metal implants, magnesium (Mg) or its alloys have shown significant advantages over other candidates attributed to not only their excellent biodegradability and suitable mechanical properties but also their osteopromotive effects for bone applications. Prior to approval mandated by the governmental regulatory body, the access to the medical market for Mg-based implants requires a series of testing for assurance of their safety and efficacy via preclinical evaluations and clinical tests including phase 1 and 2 evaluations, and phase 3 of multi-center randomized double blind and placebo-controlled clinical trials. However, as the most widely used protocols for biosafety evaluation of medical devices, current ISO 10993 standards should be carefully reevaluated when directly applying them to predict potential health risks of degradable Mg based biomaterials via cytotoxicity tests due to the huge gap between in vitro and in vivo conditions. Therefore, instead of a direct adoption, modification of current ISO standards for in vitro cytotoxicity test is desirable and justified. The differences in sensitivities of cells to in vitro and in vivo Mg ions and the capability of in vivo circulation system to dilute local degradation products were fully considered to propose modification of current ISO standards. This paper recommended a minimal 6 times to a maximal 10 times dilution of extracts for in vitro cytotoxicity test specified in ISO 10993 part 5 for pure Mg developed as potential orthopedic implants based on literature review and our specifically designed in vitro and in vivo tests presented in the study. Our work may contribute to the progress of biodegradable metals involved translational work. PMID:25890098

  4. Radiotherapy for pediatric brain tumors: Standard of care, current clinical trials, and new directions

    International Nuclear Information System (INIS)

    Objectives: To review the clinical characteristics of childhood brain tumors, including neurologic signs, neuroimaging and neuropathology. To critically assess indications for therapy relevant to presenting characteristics, age, and disease status. To discuss current management strategies including neurosurgery, radiation therapy, and chemotherapy. To analyze current clinical trials and future directions of clinical research. Brain tumors account for 20% of neoplastic diseases in children. The most common tumors include astrocytoma and malignant gliomas, medulloblastoma and supratentorial PNET's, ependymoma, craniopharyngioma, and intracranial germ cell tumors. Tumor type and clinical course are often correlated with age at presentation and anatomic site. The clinical characteristics and disease extent largely determine the relative merits of available 'standard' and investigational therapeutic approaches. Treatment outcome, including disease control and functional integrity, is dependent upon age at presentation, tumor type, and disease extent. An understanding of the clinical, neuroimaging, and histologic characteristics as they relate to decisions regarding therapy is critical to the radiation oncologist. Appropriate radiation therapy is central to curative therapy for a majority of pediatric brain tumor presentations. Technical advances in neurosurgery provide greater safety for 'gross total resection' in a majority of hemispheric astrocytomas and medulloblastomas. The relative roles of 'standard' radiation therapy and evolving chemotherapy for centrally located astrocytomas (e.g., diencephalic, optic pathway) need to be analyzed in the context of initial and overall disease control, neurotoxicities, and potential modifications in the risk:benefit ratio apparent in the introduction of precision radiation techniques. Modifications in radiation delivery are fundamental to current investigations in medulloblastoma; the rationale for contemporary and projected

  5. Standardization of the Czech version of the Snyder´s Adult dispositional hope scale

    Directory of Open Access Journals (Sweden)

    Marie Ocisková

    2016-01-01

    Full Text Available Hope is one of important factors affecting the psychological state of individuals. It influences well-being and self-esteem, academic and athletic performance, and even the probability of repeated incarceration of offenders. It also predicts the efficacy of the systematic psychotherapy of mental disorders, as well as the supportive psychotherapy in patients with oncologic illnesses. Hope has a central position in positive and clinical psychology. The aim of the presented work was to translate the adult dispositional hope scale into Czech, verify its psychometric properties and develop the norms for interpreting the resulting scores. The scale could be helpful both in mental health research and practice. 394 healthy adults participated in the study. The average age of the probands was 27.1 + 11.7 years. There were more women (n = 303; i.e. 76.9 % than men. The most common level of education was secondary (n = 309; 78.4 %. The participants were mainly students (n = 273; 69.3 % or employees and self-employed individuals (n = 113; 28.7 %. Most of them were single (n = 300; 76.1 % or married (n = 84; 21.3 %. The Adult Dispositional Hope Scale consists of 12 items. Four items measure pathways thinking (i.e. the ability to find ways to achieve one's goals and four items assess agency (i.e. goal-directed energy. The remaining four items are fillers that are not interpreted. Apart from this scale, all participants completed a demographic questionnaire and the second version of the Beck Depression Inventory. The statistical analyses consisted of the Cronbach's alpha and Spearman-Brown coefficient analysis, the exploratory and confirmatory factor analysis, the correlation between the standardized scale and the Beck Depression Inventory-II, and finally the creation of the norms based on the stens. The overall rate of hope was not statistically significantly associated with the subjects' age (Spearman r = -0.06, non-significant, nor with their sex (Mann

  6. Lifelong education for older adults in Malta: Current trends and future visions

    Science.gov (United States)

    Formosa, Marvin

    2012-04-01

    With European demographic developments causing a decline of the available workforce in the foreseeable future and the unsustainability of dominant pay-as-you-go pension systems (where contributions from the current workforce sustain pensioners), governments need to come up with strategies to deal with this upcoming challenge and to adjust their policies. Based on a study carried out between September 2009 and May 2010, this article evaluates the policies guiding late-life education in Malta, as well as the local plethora of learning opportunities for older adult education, and participation rates. The Maltese government is committed to supporting the inclusion of older persons (aged 60+) in lifelong education policies and programmes, to the extent that local studies have uncovered a recent rise in the overall participation of older adults in formal, non-formal and informal areas of learning. While the present and future prospects for late-life education in Malta seem promising, a critical scrutiny of present ideologies and trends finds the field to be no more than seductive rhetoric. Though the coordination of late-life education in Malta does result in various social benefits to older learners and Maltese society in general, it also occurs within five intersecting lines of inequality - namely an economic rationale, elitism, gender bias, the urban-rural divide and third ageism. This article ends by proposing policy recommendations for the future of late-life education.

  7. MDCT of acute colitis in adults: an update in current imaging features.

    Science.gov (United States)

    Barral, M; Boudiaf, M; Dohan, A; Hoeffel, C; Camus, M; Pautrat, K; Fishman, E K; Cohen, S; Soyer, P

    2015-02-01

    Acute colitis is often diagnosed on multidetector row computed tomography (MDCT) because patients with this condition present with abdominal pain and a variety of nonspecific symptoms. Acute colitis has multiple causes with varying degrees of severity. Analysis of the extent of colonic involvement, presence of specific MDCT imaging features and associated signs should help radiologist narrow the diagnosis. Integrating the results of clinical examination and biological tests is mandatory, and in case of ambiguous or nonspecific MDCT findings, endoscopy and colon biopsy should always be considered for a definite diagnosis. The purpose of this review is to discuss and illustrate MDCT features that are helpful for characterizing acute colitis in adults and to provide an update in current MDCT features. PMID:24835625

  8. Impacts of China's Current Appliance Standards and LabelingProgram to 2020

    Energy Technology Data Exchange (ETDEWEB)

    Fridley, David; Aden, Nathaniel; Zhou, Nan; Lin, Jiang

    2007-03-03

    The report summarizes the history and nature of China sstandardsand labeling program in the Introduction in Section 1. Trends indomestic production, exports, penetration rates, unit energy consumptionand the history of S&L technical levels by product are discussed ingreat detail in Section 2. The national energy impactsanalysis found inSection 3 concludes that overall China s standards and labeling programsreduce total electricity consumption in 2020 by an annual 106 TWh, or 16percent of what would otherwise been expected in that year in the absenceof standards and labeling programs.In total, the report concludes thatthe S&L programs currently in place in China are expected to save acumulative 1143 TWh by 2020, or 9 percent of the cumulative consumptionof residential electricity to that year. In 2020 alone, annual savingsare expected to be equivalent to 11 percent of residential electricityuse. In average generation terms, this is equivalent to 27 1-GW coalfired plants that would have required around 75 million tonnes of coal tooperate.In comparison, savings from the US appliance standards programalone is expected to save 10 percent of residential electricityconsumption in 2020.

  9. Age of First Use as a Predictor of Current Alcohol and Marijuana Use among College-Bound Emerging Adults

    Science.gov (United States)

    Bergen-Cico, Dessa K.; Lape, Megan E.

    2013-01-01

    Background: Alcohol and marijuana are the most commonly used psychoactive substances; however, the sequencing and relationship between age of first use and continued current problematic use among college-bound emerging adults is not well understood. Methods: This is a cross-sectional study of current and historical alcohol and marijuana use among…

  10. Organ dose conversion coefficients for tube current modulated CT protocols for an adult population

    Science.gov (United States)

    Fu, Wanyi; Tian, Xiaoyu; Sahbaee, Pooyan; Zhang, Yakun; Segars, William Paul; Samei, Ehsan

    2016-03-01

    In computed tomography (CT), patient-specific organ dose can be estimated using pre-calculated organ dose conversion coefficients (organ dose normalized by CTDIvol, h factor) database, taking into account patient size and scan coverage. The conversion coefficients have been previously estimated for routine body protocol classes, grouped by scan coverage, across an adult population for fixed tube current modulated CT. The coefficients, however, do not include the widely utilized tube current (mA) modulation scheme, which significantly impacts organ dose. This study aims to extend the h factors and the corresponding dose length product (DLP) to create effective dose conversion coefficients (k factor) database incorporating various tube current modulation strengths. Fifty-eight extended cardiac-torso (XCAT) phantoms were included in this study representing population anatomy variation in clinical practice. Four mA profiles, representing weak to strong mA dependency on body attenuation, were generated for each phantom and protocol class. A validated Monte Carlo program was used to simulate the organ dose. The organ dose and effective dose was further normalized by CTDIvol and DLP to derive the h factors and k factors, respectively. The h factors and k factors were summarized in an exponential regression model as a function of body size. Such a population-based mathematical model can provide a comprehensive organ dose estimation given body size and CTDIvol. The model was integrated into an iPhone app XCATdose version 2, enhancing the 1st version based upon fixed tube current modulation. With the organ dose calculator, physicists, physicians, and patients can conveniently estimate organ dose.

  11. Recruitment Issues and Strategies for Adults Who Are Not Currently Participating in Literacy and Adult Basic Education (ABE) Programs.

    Science.gov (United States)

    Kohring, Aaron

    Adult basic education (ABE) and literacy programs have used many different strategies and tools to recruit new students. A small sampling of Tennessee ABE programs shows the more effective recruitment strategies are word-of-mouth referrals; newspaper advertisements and articles; fliers; brochures; posters, radio messages, and public service…

  12. Clinical compliance of viewing conditions in radiology reporting environments against current guidelines and standards

    Science.gov (United States)

    Daly, S.; Rainford, L.; Butler, M. L.

    2014-03-01

    Several studies have demonstrated the importance of environmental conditions in the radiology reporting environment, with many indicating that incorrect parameters could lead to error and misinterpretation. Literature is available with recommendations as to the levels that should be achieved in clinical practice, but evidence of adherence to these guidelines in radiology reporting environments is absent. This study audited the reporting environments of four teleradiologist and eight hospital based radiology reporting areas. This audit aimed to quantify adherence to guidelines and identify differences in the locations with respect to layout and design, monitor distance and angle as well as the ambient factors of the reporting environments. In line with international recommendations, an audit tool was designed to enquire in relation to the layout and design of reporting environments, monitor angle and distances used by radiologists when reporting, as well as the ambient factors such as noise, light and temperature. The review of conditions were carried out by the same independent auditor for consistency. The results obtained were compared against international standards and current research. Each radiology environment was given an overall compliance score to establish whether or not their environments were in line with recommended guidelines. Poor compliance to international recommendations and standards among radiology reporting environments was identified. Teleradiology reporting environments demonstrated greater compliance than hospital environments. The findings of this study identified a need for greater awareness of environmental and perceptual issues in the clinical setting. Further work involving a larger number of clinical centres is recommended.

  13. Transcranial direct current stimulation of the primary motor cortex improves word-retrieval in older adults.

    Directory of Open Access Journals (Sweden)

    Marcus eMeinzer

    2014-09-01

    Full Text Available Language facilitation by transcranial direct current stimulation (tDCS in healthy individuals has generated hope that tDCS may also allow improving language impairment after stroke (aphasia. However, current stimulation protocols have yielded variable results and may require identification of residual language cortex using functional magnetic resonance imaging (fMRI, which complicates incorporation into clinical practice. Based on previous behavioral studies that demonstrated improved language processing by motor system pre-activation, the present study assessed whether tDCS administered to the primary motor cortex (M1 can enhance language functions.This proof-of-concept study employed a sham-tDCS controlled, cross-over, within-subject design and assessed the impact of unilateral excitatory (anodal and bihemispheric (dual tDCS in eighteen healthy older adults during semantic word-retrieval and motor speech tasks. Simultaneous fMRI scrutinized the neural mechanisms underlying tDCS effects.Both active tDCS conditions significantly improved word-retrieval compared to sham-tDCS. The direct comparison of activity elicited by word-retrieval vs. motor-speech trials revealed bilateral frontal activity increases during both anodal- and dual-tDCS compared to sham-tDCS. This effect was driven by more pronounced deactivation of frontal regions during the motor-speech task, while activity during word-retrieval trials was unaffected by the stimulation. No effects were found in M1 and secondary motor regions.Our results show that tDCS administered to M1 can improve word-retrieval in healthy individuals, thereby providing a rationale to explore whether M1-tDCS may offer a novel approach to improve language functions in aphasia. fMRI revealed neural facilitation specifically during motor speech trials, which may have reduced switching costs between the overlapping neural systems for lexical retrieval and speech processing, thereby resulting in improved

  14. The Association of Current Violence from Adult Family Members with Adolescent Bullying Involvement and Suicidal Feelings

    Science.gov (United States)

    Shimodera, Shinji; Koike, Shinsuke; Usami, Satoshi; Toriyama, Rie; Kanata, Sho; Sasaki, Tsukasa; Kasai, Kiyoto; Okazaki, Yuji; Nishida, Atsushi

    2016-01-01

    Although several studies have reported that child physical abuse increased the risk for bullying involvement, the effect of current violence from adult family members (CVA) on bullying involvement and suicidal feelings among adolescents has not been sufficiently examined. This study investigated the association of CVA with adolescent bullying involvement and the interaction effect of CVA and bullying involvement on suicidal feelings. This cross-sectional study used data from a school-based survey with a general population of adolescents (grades 7 to 12). Data were collected using a self-report questionnaire completed by 17,530 students. Logistic regression analyses were performed to explore the association of CVA with adolescent bullying involvement and suicidal feelings. The overall response rate was 90.2%. The odds of students being characterized as bullies, victims, and bully-victims were higher among adolescents with CVA than without CVA (odds ratios (OR) = 2.9, 95% confidence interval (CI), [2.3–3.7], 4.6 [3.6–5.8], and 5.8 [4.4–7.6], respectively). Both CVA (OR = 3.4 [95% CI 2.7–4.3]) and bullying (bullies, victims, and bully-victims; OR = 2.0 [95% CI 1.6–2.6], 4.0 [3.1–5.1], 4.1 [3.0–5.6], respectively), were associated with increased odds of current suicidal feelings after adjusting for confounding factors. Furthermore, positive additive effects of CVA and all three types of bullying involvement on suicidal feelings were found. For example, bully-victims with CVA had about 19-fold higher odds of suicidal feelings compared with uninvolved adolescents without CVA. This study, although correlational, suggested that CVA avoidance might prevent bullying involvement and suicidal feelings in adolescents. PMID:27711150

  15. Adult leukaemia: what is the role of currently known risk factors?

    Energy Technology Data Exchange (ETDEWEB)

    Zeeb, H. [Deutsches Krebsforschungszentrum, Abt. Epidemiologie, Im Neuenheimer Feld 280, D-69120 Heidelberg (Germany); Blettner, M. [International Agency for Research on Cancer (IARC), Unit of Carcinogen Identification and Evaluation, 150 Cours Albert Thomas, F-69372 Lyon (France)

    1998-02-01

    Leukaemias are a heterogeneous group of tumours including acute and chronic forms. Considerable efforts have been made to identify risk factors for these diseases, but only a minority of leukaemia cases can currently be attributed to identified or hypothesized factors. This review highlights recent epidemiological literature concerning adult leukaemia, discussing in detail the hereditary, environmental and medical risks. Chromosomal syndromes and genetically based diseases carry a high risk of leukaemia, but rarely occur in the population. Environmental and occupational exposures to chemicals including pesticides have been widely studied, although the results are not consistent, with the exception of benzene. Smoking seems to be a weak causal risk factor. The risk of ionizing radiation has further been quantified in recent studies, although the effects of low doses have not yet been clarified. The results for non-ionizing radiation continue to be inconsistent, but a large effect of electromagnetic fields on the risk of leukaemia appears to be unlikely. Medically applied radio- and chemotherapy are clearly associated with subsequent leukaemia development, and there are links between leukaemia and viral infections. Future research should emphasize the shortcomings in exposure assessment that pervade many studies, and interactions between different risk factors need to be taken into consideration. (orig.) With 1 fig., 5 tabs., 114 refs.

  16. Childhood Trauma and Current Psychological Functioning in Adults with Social Anxiety Disorder

    OpenAIRE

    Kuo, Janice R.; Goldin, Philippe R.; Werner, Kelly; Heimberg, Richard G.; Gross, James J.

    2010-01-01

    Etiological models of social anxiety disorder (SAD) suggest that early childhood trauma contributes to the development of this disorder. However, surprisingly little is known about the link between different forms of childhood trauma and adult clinical symptoms in SAD. This study (1) compared levels of childhood trauma in adults with generalized SAD versus healthy controls (HCs), and (2) examined the relationship between specific types of childhood trauma and adult clinical symptoms in SAD. P...

  17. Revision of the Euratom basic safety standards directive-current status

    International Nuclear Information System (INIS)

    The European Commission is currently developing a revised Euratom Basic Safety Standards (BSS) Directive covering two major objectives: the consolidation of existing Euratom Radiation Protection legislation and the revision of the Euratom BSS. The consolidation will merge the following five Directives into one single Directive: the BSS Directive, the Medical Exposures Directive, the Public Information Directive, the Outside Workers Directive and the Directive on the Control of high-activity sealed radioactive sources and orphan sources. The revision of the Euratom BSS will take account of the latest recommendations by the International Commission on Radiological Protection and shall improve clarity of the requirements where appropriate. It is planned to introduce more binding requirements on natural radiation sources, on criteria for exemption and clearance, and on the cooperation between Member States for emergency planning and response. The provisions for regulatory control of planned exposure situations foresee a graded approach commensurate to the magnitude and likelihood of exposures from a practice. Finally, the new BSS shall take account of recent scientific developments. One additional goal is to achieve greater harmonisation between the Euratom BSS and the international BSS. While the requirements on the protection of workers, apprentices and students remain nearly unchanged, the revised BSS will clarify the roles and responsibilities of services and experts involved in technical and practical aspects of radiation protection, such as the occupational health services, the dosimetry services, the radiation protection expert and the medical physics expert. The requirements in the BSS on individual monitoring of category A workers remain unchanged, but the existing guidance on individual monitoring was revised and updated-the technical recommendations for monitoring individuals occupationally exposed to external radiation are published by the European

  18. Item Response Theory Analyses of Adult Self-Ratings of the ADHD Symptoms in the Current Symptoms Scale

    Science.gov (United States)

    Gomez, Rapson

    2011-01-01

    The graded response model, which is based on item response theory, was used to evaluate the psychometric properties of adult self-ratings (N = 852) of the attention deficit/hyperactivity disorder inattention, hyperactivity, and impulsivity symptoms presented in the Current Symptoms Scale. This scale has four ordered response categories. The…

  19. Behavioural methods used in rodent models of autism spectrum disorders: current standards and new developments.

    Science.gov (United States)

    Wöhr, Markus; Scattoni, Maria Luisa

    2013-08-15

    Autism is a behaviourally defined disorder including attenuated or abnormal social interaction and communication, as well as aberrant repetitive behaviour, with symptoms emerging early in childhood. Although the cause of autism has not been discovered, several data strongly support the role of genetic factors in autism aetiology. For this reason, preclinical research is now focusing on generating transgenic and knockout mice, and more recently also rats, with mutations in genes identified in autistic children, with the main aim of understanding the role of those genes in autism aetiology, discovering the biological mechanisms underlying autistic behaviours detected in these mutant lines and evaluating potential treatments. Over the last years, a huge number of behavioural phenotyping assays for rodent models of autism and related disorders have been designed. In the first part of our review, we focus on current standards, i.e. state-of-the-art behavioural phenotyping tasks to assess autism core symptoms in rodent models. The second part is devoted to some few, in our view, very promising examples of new developments, namely an autism severity score, scent marking behaviour as an additional, ethologically valid measure for communication, plus a number of new developments in the behavioural domains of social facilitation, observational learning, and empathy. Finally, we will highlight the huge potential impact of newly generated rat knockout models of autism. PMID:23769995

  20. Taper Preparation Variability Compared to Current Taper Standards Using Computed Tomography

    Directory of Open Access Journals (Sweden)

    Richard Gergi

    2012-01-01

    Full Text Available Introduction. The purpose of this study was to compare the taper variation in root canal preparations among Twisted Files and PathFiles-ProTaper .08 tapered rotary files to current standards. Methods. 60 root canals with severe angle of curvature (between 25∘ and 35∘ and short radius (<10 mm were selected. The canals were divided randomly into two groups of 30 each. After preparation with Twisted Files and PathFiles-ProTaper to size 25 taper .08, the diameter was measured using computed tomography (CT at 1, 3, and 16 mm. Canal taper preparation was calculated at the apical third and at the middle-cervical third. Results. Of the 2 file systems, both fell within the ±.05 taper variability. All preparations demonstrated variability when compared to the nominal taper .08. In the apical third, mean taper was significantly different between TF and PathFiles-ProTaper ( value < 0.0001; independent -test. Mean Taper was significantly higher with PathFile-ProTaper. In the middle-cervical third, mean Taper was significantly higher with TF ( value = 0.015; independent -test. Conclusion. Taper preparations of the investigated size 25 taper .08 were favorable but different from the nominal taper.

  1. The dark matter crisis: falsification of the current standard model of cosmology

    CERN Document Server

    Kroupa, Pavel

    2012-01-01

    The current standard model of cosmology (SMoC) requires The Dual Dwarf Galaxy Theorem to be true. According to this theorem two types of dwarf galaxies must exist: primordial dark-matter (DM) dominated (type A) dwarf galaxies, and tidal-dwarf and ram-pressure-dwarf (type B) galaxies void of DM. In the model, type A dwarfs are distributed approximately spherically following the shape of the host galaxy DM halo, while type B dwarfs are typically correlated in phase-space. Type B dwarfs must exist in any cosmological theory in which galaxies interact. Only one type of dwarf galaxy is observed to exist on the baryonic Tully-Fisher plot and in the radius-mass plane. The Milky Way satellite system forms a vast phase-space-correlated structure that includes globular clusters and stellar and gaseous streams. Similar arguments apply to Andromeda. Other galaxies also have phase-space correlated satellite systems. Therefore, The Dual Galaxy Theorem is falsified by observation and dynamically relevant cold or warm DM on ...

  2. XBRL Standard for Financial Reporting in Croatia: Current State and Perspectives

    Directory of Open Access Journals (Sweden)

    Gostimir Dejan

    2015-09-01

    Full Text Available Background: Harmonization and standardization is becoming important among regulators and business community. XBRL has entered the global stage as a financial reporting standard. Its mission was to standardize the financial reporting, lower the reporting costs and make the reporting as transparent as possible.

  3. Computational dosimetry for child and adult human models due to contact current from 10 Hz to 110 MHz

    International Nuclear Information System (INIS)

    This study computationally investigates in situ electric field due to low-frequency contact current and specific absorption rate (SAR) due to high-frequency contact currents in a realistic child model and compared with those in the adult model. The in situ electric fields and SAR in the child model are found to exceed the corresponding values in the adult. At the finger tip, the electric field and SAR due to contact currents, both at the ICNIRP reference levels and IEEE Maximum Permissible Exposures, are well beyond the corresponding basic restrictions. In the remaining part, the largest difference was observed in spinal tissue, and the smallest effect was in the heart. With respect to brain and skin conductivities, one needs to strongly consider which values of tissue properties are used to interpret one's results. The in situ electric fields resulting from contact with the metal plane are similar to those for contact with the wire. (authors)

  4. Current Concept for the Diagnosis and Treatment of Adult Idiopathic Thrombocytopenic Purpura

    Institute of Scientific and Technical Information of China (English)

    侯明

    2005-01-01

    @@ Idiopathic thrombocytopenic purpura (ITP) is a common hematologic disorder manifested by immunemediated thrombocytopenia. The estimated incidence ranges from 50 ~ 100 per million each year in western countries, roughly divided between adults and children.

  5. Predicting the efficacy of trastuzumab-based therapy in breast cancer: current standards and future strategies.

    Science.gov (United States)

    Singer, Christian F; Köstler, Wolfgang J; Hudelist, Gernot

    2008-12-01

    Breast cancer is the most common female malignancy in many industrialized countries. Approximately one fourth of all women diagnosed with early breast cancer present with tumors that are characterized by erbB2 amplification. While the associated Her-2/neu receptor overexpression results in a high risk of relapse and poor prognosis, these tumors also represent a target for a selective monoclonal antibody therapy with trastuzumab (Herceptin). The combination of trastuzumab with chemotherapy has led to a considerable reduction of recurrences and to a significant reduction in breast cancer mortality both in the adjuvant and metastatic setting. Unfortunately, despite Her-2/neu overexpression, not all patients equally benefit from trastuzumab treatment, and almost all women with metastatic breast cancer eventually progress during antibody therapy. Moreover, trastuzumab is burdened with cardiotoxicity, thus increasing the risk of symptomatic congestive heart failure. In addition, the marginal costs for a 1 year therapy of trastuzumab-based therapy, which is currently considered to be the most effective treatment regimen in the adjuvant setting, may amount for up to US$ 40.000. Testing for erbB2 oncogene amplification by fluorescence in situ hybridization (FISH) and chromogenic in situ hybridization (CISH), respectively, and staining for Her-2/neu receptor overexpression by immunohistochemistry (IHC) represent the current standard for determining patient eligibility for trastuzumab-based therapy. However, while the negative predictive value of these assays for predicting the absence of benefit from trastuzumab-based therapy is sufficiently high, their positive predictive value remains insufficient, i.e. only a proportion of patients selected by these tests substantially benefit from trastuzumab-containing regimen. Accordingly, over the last years a number of biomarkers have been evaluated in their potential to predict response to trastuzumab-based therapies. These include

  6. Calculation of Initial Short-Circuit Currents in Medium Voltage Networks According to the Standard PN-EN 60909

    OpenAIRE

    Krzysztof Księżyk; Tomasz Zdun

    2013-01-01

    Determining the short-circuit currents is usually conducted by network analyses. An important feature of this calculation is carried out according to the recommendations of the standard PN EN 60909. This paper describes the models of the basic elements of the network with the method of determining the impedance parameters including correction factors introduced by the standard. Thevenin’s method connected with the nodal method are presented and used to determine the initial short-circuit f...

  7. NODC Standard Product: Ocean current drifter data (2 disc set) (NODC Accession 0098060)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — These CD-ROMs hold over 4 million surface current observations, almost all obtained by the ship drift method. Date, data source, position, and current direction and...

  8. Effects of transcranial direct current stimulation on the control of finger force during dexterous manipulation in healthy older adults.

    Directory of Open Access Journals (Sweden)

    Pranav J Parikh

    Full Text Available The contribution of poor finger force control to age-related decline in manual dexterity is above and beyond ubiquitous behavioral slowing. Altered control of the finger forces can impart unwanted torque on the object affecting its orientation, thus impairing manual performance. Anodal transcranial direct current stimulation (tDCS over primary motor cortex (M1 has been shown to improve the performance speed on manual tasks in older adults. However, the effects of anodal tDCS over M1 on the finger force control during object manipulation in older adults remain to be fully explored. Here we determined the effects of anodal tDCS over M1 on the control of grip force in older adults while they manipulated an object with an uncertain mechanical property. Eight healthy older adults were instructed to grip and lift an object whose contact surfaces were unexpectedly made more or less slippery across trials using acetate and sandpaper surfaces, respectively. Subjects performed this task before and after receiving anodal or sham tDCS over M1 on two separate sessions using a cross-over design. We found that older adults used significantly lower grip force following anodal tDCS compared to sham tDCS. Friction measured at the finger-object interface remained invariant after anodal and sham tDCS. These findings suggest that anodal tDCS over M1 improved the control of grip force during object manipulation in healthy older adults. Although the cortical networks for representing objects and manipulative actions are complex, the reduction in grip force following anodal tDCS over M1 might be due to a cortical excitation yielding improved processing of object-specific sensory information and its integration with the motor commands for production of manipulative forces. Our findings indicate that tDCS has a potential to improve the control of finger force during dexterous manipulation in older adults.

  9. Current Climate Data Set Documentation Standards: Somewhere between Anagrams and Full Disclosure

    Science.gov (United States)

    Fleig, A. J.

    2008-12-01

    techniques are being developed that will simplify the creation of much of the provenance information but there are both cultural and infrastructure problems that discourage provision of complete documentation. It is time to reconsider what the standards for production and documentation of data sets should be. There is only a short window before the loss of knowledge about current data sets associated with human mortality becomes irreversible. .

  10. Current cigarette smoking among adults--United States, 2005-2013.

    Science.gov (United States)

    Jamal, Ahmed; Agaku, Israel T; O'Connor, Erin; King, Brian A; Kenemer, John B; Neff, Linda

    2014-11-28

    Tobacco use is the leading cause of preventable disease and death in the United States, resulting in more than 480,000 premature deaths and $289 billion in direct health care expenditures and productivity losses each year. Despite progress over the past several decades, millions of adults still smoke cigarettes, the most commonly used tobacco product in the United States. To assess progress made toward the Healthy People 2020 target of reducing the proportion of U.S. adults who smoke cigarettes to ≤12.0% (objective TU-1.1), CDC used data from the 2013 National Health Interview Survey (NHIS) to provide updated national estimates of cigarette smoking prevalence among adults aged ≥18 years. Additionally, for the first time, estimates of cigarette smoking prevalence were assessed among lesbian, gay, or bisexual persons (LGB) using NHIS data. The proportion of U.S. adults who smoke cigarettes declined from 20.9% in 2005 to 17.8% in 2013, and the proportion of daily smokers declined from 16.9% to 13.7%. Among daily cigarette smokers, the proportion who smoked 20-29 cigarettes per day (CPD) declined from 34.9% to 29.3%, and the proportion who smoked ≥30 CPD declined from 12.7% to 7.1%. However, cigarette smoking remains particularly high among certain groups, including adults who are male, younger, multiracial or American Indian/Alaska Native, have less education, live below the federal poverty level, live in the South or Midwest, have a disability/limitation, or who are LGB. Proven population-based interventions, including tobacco price increases, comprehensive smoke-free policies in worksites and public places, high-impact anti-tobacco mass media campaigns, and easy access to smoking cessation assistance, are critical to reducing cigarette smoking and smoking-related disease and death among U.S. adults, particularly among subpopulations with the greatest burden. PMID:25426653

  11. Standard methods for maintaining adult Apis mellifera in cages under in vitro laboratory conditions

    NARCIS (Netherlands)

    Williams, G.R.; Alaux, C.; Costa, C.; Csaki, C.; Steen, van der J.J.M.

    2013-01-01

    Adult honey bees are maintained in vitro in laboratory cages for a variety of purposes. For example, researchers may wish to perform experiments on honey bees caged individually or in groups to study aspects of parasitology, toxicology, or physiology under highly controlled conditions, or they may c

  12. Current issues around the pharmacotherapy of ADHD in children and adults

    NARCIS (Netherlands)

    Meijer, W.M.; Faber, A.; Ban, van den E.; Tobi, H.

    2009-01-01

    Background New drugs and new formulations enter the growing market for ADHD medication. The growing awareness of possible persistence of ADHD impairment beyond childhood and adolescence resulting in increased pharmacotherapy of ADHD in adults, is also a good reason for making an inventory of the wha

  13. Premarital Sexual Attitudes and Behavior of Adolescents and Young Adults: A Review of Current Literature.

    Science.gov (United States)

    Turnquist, Bruce Eric

    This document reviews research concerning the factors affecting premarital sexual attitudes and behaviors of adolescents and young adults. Trends in the literature prior to 1980 are discussed briefly together with summaries of literature reviews from the decades of the 1950s, 1960s, and 1970s. Studies from 1980 to the present are reviewed in some…

  14. Historical Development of NATO Stanag 6001 Language Standards and Common European Framework (CEF) and the Comparison of Their Current Status

    Science.gov (United States)

    Solak, Ekrem

    2011-01-01

    The aim of the article is to shed light on the historical development of language studies in military and social context and to compare the current status of NATO Stanag (Standard Agreement) 6001 language scale with Common European Framework (CEF). Language studies in military context date back to World War II and the emergence of Army Specialized…

  15. 75 FR 22150 - Current List of Laboratories Which Meet Minimum Standards To Engage in Urine Drug Testing for...

    Science.gov (United States)

    2010-04-27

    ... HUMAN SERVICES Substance Abuse and Mental Health Services Administration Current List of Laboratories Which Meet Minimum Standards To Engage in Urine Drug Testing for Federal Agencies Correction In notice... for ACM Medical Laboratory, Inc. and Advanced Toxicology Network were combined. The listings should...

  16. Institutional abuse of children in the Austrian Catholic Church: types of abuse and impact on adult survivors' current mental health.

    Science.gov (United States)

    Lueger-Schuster, Brigitte; Kantor, Viktoria; Weindl, Dina; Knefel, Matthias; Moy, Yvonne; Butollo, Asisa; Jagsch, Reinhold; Glück, Tobias

    2014-01-01

    The aim of this study was to explore the nature and dimensions of institutional child abuse (IA) by the Austrian Catholic Church and to investigate the current mental health of adult survivors. Data were collected in two steps. First, documents of 448 adult survivors of IA (M=55.1 years, 75.7% men) who had disclosed their abuse history to a victim protection commission were collected. Different types of abuse, perpetrator characteristics, and family related risk factors were investigated. Second, a sample of 185 adult survivors completed the Posttraumatic Stress Disorder Checklist (PCL-C) and the Brief Symptom Inventory (BSI). Participants reported an enormous diversity of acts of violent physical, sexual, and emotional abuse that had occurred in their childhood. The majority of adult survivors (83.3%) experienced emotional abuse. Rates of sexual (68.8%) and physical abuse (68.3%) were almost equally high. The prevalence of PTSD was 48.6% and 84.9% showed clinically relevant symptoms in at least one 1 of 10 symptom dimensions (9 BSI subscales and PTSD). No specific pre-IA influence was found to influence the development of PTSD in later life (e.g. poverty, domestic violence). However, survivors with PTSD reported a significantly higher total number of family related risk factors (d=0.33). We conclude that childhood IA includes a wide spectrum of violent acts, and has a massive negative impact on the current mental health of adult survivors. We address the long-term effects of these traumatic experiences in addition to trauma re-activation in adulthood as both bear great challenges for professionals working with survivors. PMID:24018068

  17. Institutional abuse of children in the Austrian Catholic Church: types of abuse and impact on adult survivors' current mental health.

    Science.gov (United States)

    Lueger-Schuster, Brigitte; Kantor, Viktoria; Weindl, Dina; Knefel, Matthias; Moy, Yvonne; Butollo, Asisa; Jagsch, Reinhold; Glück, Tobias

    2014-01-01

    The aim of this study was to explore the nature and dimensions of institutional child abuse (IA) by the Austrian Catholic Church and to investigate the current mental health of adult survivors. Data were collected in two steps. First, documents of 448 adult survivors of IA (M=55.1 years, 75.7% men) who had disclosed their abuse history to a victim protection commission were collected. Different types of abuse, perpetrator characteristics, and family related risk factors were investigated. Second, a sample of 185 adult survivors completed the Posttraumatic Stress Disorder Checklist (PCL-C) and the Brief Symptom Inventory (BSI). Participants reported an enormous diversity of acts of violent physical, sexual, and emotional abuse that had occurred in their childhood. The majority of adult survivors (83.3%) experienced emotional abuse. Rates of sexual (68.8%) and physical abuse (68.3%) were almost equally high. The prevalence of PTSD was 48.6% and 84.9% showed clinically relevant symptoms in at least one 1 of 10 symptom dimensions (9 BSI subscales and PTSD). No specific pre-IA influence was found to influence the development of PTSD in later life (e.g. poverty, domestic violence). However, survivors with PTSD reported a significantly higher total number of family related risk factors (d=0.33). We conclude that childhood IA includes a wide spectrum of violent acts, and has a massive negative impact on the current mental health of adult survivors. We address the long-term effects of these traumatic experiences in addition to trauma re-activation in adulthood as both bear great challenges for professionals working with survivors.

  18. 我国乳品标准体系现状%Current Status of China s Dairy Product Standards System

    Institute of Scientific and Technical Information of China (English)

    幸汐媛; 李江华

    2011-01-01

    近年来乳品安全事件频繁发生,本文通过介绍我国乳品标准体系的发展和乳品标准体系的特点,对我国现行的在奶畜养殖环节、生产加工环节和流通环节的乳品国家标准、行业标准进行相关阐述,分析我国乳品标准体系的现状。%Dairy safety incidents occur frequently in recent years.This article introduces the development and features of China s dairy product standards system,and summarizes and analyzes the current national and industrial standards for dairy products concerning cow breeding,production,processing,and circulation.Meanwhile,a review of the current status of China s dairy product standards system is provided.

  19. Application of Pulsed Eddy Current for Depth Measurement of Steam Generator's Wear scar tube standard

    International Nuclear Information System (INIS)

    The integrity of stem generator tube in nuclear power plant is the critical problem but the particular area on the stem generator tube could be worn away by inside impurities, fluid flow and vibration from the outside environment. At the present, the inspection of stem generator tube has been performed by using a conventional eddy current testing. Although the conventional eddy current testing is a powerful method to detect flaws of tube in online processing, it is difficult to measure the deep depth differences of the tube. Because eddy current density has changed its magnitude with distance from the surface. Whereas, the pulsed eddy current technique has been widely employed for deep depth inspection of structures such as plate, tubes. For more effective inspection, the pulsed eddy current system is enveloped to control a depth difference and submitted the multi-pointing method to select a criteria which could be obtained depth differences by the period of resistivity on the pulsed eddy current transient signals. In this paper, we used the pulsed eddy current technique to improve the capability of depth difference measurement and studied multi-pointing method to evaluate the thickness with variation of resistivity.

  20. Comparison of two standardized methods of methacholine inhalation challenge in young adults

    DEFF Research Database (Denmark)

    Siersted, H C; Walker, C M; O'Shaughnessy, A D;

    2000-01-01

    In the European Community Respiratory Health Study (ECRHS), airway responsiveness to methacholine was determined using the Mefar dosimeter protocol. Elsewhere, the 2-min tidal breathing method has become the preferred standardized method. The relationship between measurements of responsiveness by...

  1. Treatment of a giant congenital melanocytic nevus in the adult: review of the current management of giant congenital melanocytic nevus.

    Science.gov (United States)

    Su, Jeannie J; Chang, Daniel K; Mailey, Brian; Gosman, Amanda

    2015-05-01

    Giant congenital melanocytic nevi (GCMNs) create cosmetic disfigurements and pose risk for malignant transformation. Adult GCMN cases are uncommon because most families opt for surgical treatment during childhood. We review the current literature on GCMN and present an interesting case of an adult with a GCMN encompassing the entire back with painful nodules exhibiting gross involvement of his back musculature, without pathologic evidence of malignancy. Surgical management was deferred in childhood because of parental desires to allow the patient to make his own decision, and treatment in adulthood was pursued on the basis of the significant impairment of the patient's quality of life and self-esteem due to the massive size and deforming nature of the nevus. The treatment strategy used for this young adult male patient involved a massive en bloc excision of the GCMN with partial resection of the latissimus dorsi, followed by a 5-week staged reconstructive process using dermal regenerative matrices and split-thickness skin grafting. Because of the shift in GCMN management from early surgical management to more conservative management, we may see an increase in adult cases of GCMN. Thus, it is critical to better understand the controversy surrounding early versus delayed management of GCMN. PMID:25664413

  2. Older Adults' Current and Potential Uses of Information Technologies in a Changing World: A Theoretical Perspective.

    Science.gov (United States)

    Backonja, Uba; Hall, Amanda K; Thielke, Stephen

    2014-12-01

    Technologies have become a major force in people's lives. They change how people interact with the environment, even as the environment changes. We propose that technology use in the setting of changing environments is motivated by essential needs and tensions experienced by the individual. We apply three developmental and behavioral theories (Erikson's stages of psychosocial development, Maslow's hierarchy of needs, and Bronfenbrenner's ecological model) to explain technology-related behaviors among older adults. We consider how technology use has addressed and can address major ecological changes, in three areas: health promotion, natural disasters, and disparities. We propose that considering these theories can help researchers and developers ensure that technologies will help promote a healthier world for older adults.

  3. Older Adults' Current and Potential Uses of Information Technologies in a Changing World: A Theoretical Perspective.

    Science.gov (United States)

    Backonja, Uba; Hall, Amanda K; Thielke, Stephen

    2014-12-01

    Technologies have become a major force in people's lives. They change how people interact with the environment, even as the environment changes. We propose that technology use in the setting of changing environments is motivated by essential needs and tensions experienced by the individual. We apply three developmental and behavioral theories (Erikson's stages of psychosocial development, Maslow's hierarchy of needs, and Bronfenbrenner's ecological model) to explain technology-related behaviors among older adults. We consider how technology use has addressed and can address major ecological changes, in three areas: health promotion, natural disasters, and disparities. We propose that considering these theories can help researchers and developers ensure that technologies will help promote a healthier world for older adults. PMID:26215298

  4. Comparison of current practices of cardiopulmonary perfusion technology in Iran with American Society of Extracorporeal Technology’s standards

    Science.gov (United States)

    Faravan, Amir; Mohammadi, Nooredin; Alizadeh Ghavidel, Alireza; Toutounchi, Mohammad Zia; Ghanbari, Ameneh; Mazloomi, Mehran

    2016-01-01

    Introduction: Standards have a significant role in showing the minimum level of optimal optimum and the expected performance. Since the perfusion technology staffs play an the leading role in providing the quality services to the patients undergoing open heart surgery with cardiopulmonary bypass machine, this study aimed to assess the standards on how Iranian perfusion technology staffs evaluate and manage the patients during the cardiopulmonary bypass process and compare their practice with the recommended standards by American Society of Extracorporeal Technology. Methods: In this descriptive study, data was collected from 48 Iranian public hospitals and educational health centers through a researcher-created questionnaire. The data collection questionnaire assessed the standards which are recommended by American Society of Extracorporeal Technology. Results: Findings showed that appropriate measurements were carried out by the perfusion technology staffs to prevent the hemodilution and avoid the blood transfusion and unnecessary blood products, determine the initial dose of heparin based on one of the proposed methods, monitor the anticoagulants based on ACT measurement, and determine the additional doses of heparin during the cardiopulmonary bypass based on ACT or protamine titration. It was done only in 4.2% of hospitals and health centers. Conclusion: Current practices of cardiopulmonary perfusion technology in Iran are inappropriate based on the standards of American Society of Cardiovascular Perfusion. This represents the necessity of authorities’ attention to the validation programs and development of the caring standards on one hand and continuous assessment of using these standards on the other hand. PMID:27489600

  5. Adult stem cells in neural repair: Current options,limitations and perspectives

    Institute of Scientific and Technical Information of China (English)

    Eric Domingos Mariano; Manoel Jacobsen Teixeira; Suely Kazue Nagahashi Marie; Guilherme Lepski

    2015-01-01

    Stem cells represent a promising step for the future ofregenerative medicine. As they are able to differentiateinto any cell type, tissue or organ, these cells are greatcandidates for treatments against the worst diseasesthat defy doctors and researchers around the world.Stem cells can be divided into three main groups (1)embryonic stem cells; (2) fetal stem cells; and (3) adultstem cells. In terms of their capacity for proliferation,stem cells are also classified as totipotent, pluripotentor multipotent. Adult stem cells, also known as somaticcells, are found in various regions of the adult organism,such as bone marrow, skin, eyes, viscera and brain.They can differentiate into unipotent cells of theresiding tissue, generally for the purpose of repair.These cells represent an excellent choice in regenerativemedicine, every patient can be a donor of adult stemcells to provide a more customized and efficient therapyagainst various diseases, in other words, they allow theopportunity of autologous transplantation. But in orderto start clinical trials and achieve great results, we needto understand how these cells interact with the hosttissue, how they can manipulate or be manipulated bythe microenvironment where they will be transplantedand for how long they can maintain their multipotentstate to provide a full regeneration.

  6. Current practices and challenges in the standardization and harmonization of clinical laboratory tests.

    Science.gov (United States)

    Vesper, Hubert W; Myers, Gary L; Miller, W Greg

    2016-09-01

    Effective patient care, clinical research, and public health efforts require comparability of laboratory results independent of time, place, and measurement procedure. Comparability is achieved by establishing metrological traceability, which ensures that measurement procedures measure the same quantity and that the calibration of measurement procedures is traceable to a common reference system consisting of reference methods and materials. Whereas standardization ensures traceability to the International System of Units, harmonization ensures traceability to a reference system agreed on by convention. This article provides an overview of standardization and harmonization with an emphasis on commutability as an important variable that affects testing accuracy. Commutability of reference materials is required to ensure that traceability is established appropriately and that laboratory results are comparable. The use of noncommutable reference materials leads to inaccurate results. Whereas procedures and protocols for standardizing measurements are established and have been successfully applied in efforts such as the Hormones Standardization Program of the CDC, harmonization activities require new, more complex procedures and approaches. The American Association for Clinical Chemistry, together with its domestic and international partners, formed the International Consortium for Harmonization of Clinical Laboratory Results to coordinate harmonization efforts. Reference systems, as well as procedures and protocols to establish traceability of clinical laboratory tests, have been established and continue to be developed by national and international groups and organizations. Serum tests of thyroid function, including those for the thyroid hormones thyroxine and triiodothyronine, are among the clinical procedures for which standardization efforts are well under way. Approaches to the harmonization of measurement procedures for serum concentrations of thyroid

  7. Adult subependymal neural precursors, but not differentiated cells, undergo rapid cathodal migration in the presence of direct current electric fields.

    Directory of Open Access Journals (Sweden)

    Robart Babona-Pilipos

    Full Text Available BACKGROUND: The existence of neural stem and progenitor cells (together termed neural precursor cells in the adult mammalian brain has sparked great interest in utilizing these cells for regenerative medicine strategies. Endogenous neural precursors within the adult forebrain subependyma can be activated following injury, resulting in their proliferation and migration toward lesion sites where they differentiate into neural cells. The administration of growth factors and immunomodulatory agents following injury augments this activation and has been shown to result in behavioural functional recovery following stroke. METHODS AND FINDINGS: With the goal of enhancing neural precursor migration to facilitate the repair process we report that externally applied direct current electric fields induce rapid and directed cathodal migration of pure populations of undifferentiated adult subependyma-derived neural precursors. Using time-lapse imaging microscopy in vitro we performed an extensive single-cell kinematic analysis demonstrating that this galvanotactic phenomenon is a feature of undifferentiated precursors, and not differentiated phenotypes. Moreover, we have shown that the migratory response of the neural precursors is a direct effect of the electric field and not due to chemotactic gradients. We also identified that epidermal growth factor receptor (EGFR signaling plays a role in the galvanotactic response as blocking EGFR significantly attenuates the migratory behaviour. CONCLUSIONS: These findings suggest direct current electric fields may be implemented in endogenous repair paradigms to promote migration and tissue repair following neurotrauma.

  8. Radiotherapy for pediatric brain tumors: Standards of care, current clinical trials, and new directions

    International Nuclear Information System (INIS)

    The objectives of the course are to evaluate the role of radiation therapy in the treatment of pediatric brain tumors. Areas where the role is evolving will be identified, and the results of clinical trials which been mounted to clarify radiotherapy's role will be reviewed. Brain tumors are the second most common malignancy of childhood after leukemias and lymphomas. However, they remain the most common group of childhood tumors to require radiation therapy. Therefore, a thorough understanding of these tumors, and the appropriate role of surgery, radiation and chemotherapy is critical. Issues surrounding the management of sequelae are no less important. The role of radiotherapy for the treatment of these tumors is far different from that for adults. These differences relate to the profound potential for sequelae from therapy, the higher overall cure rates, and the utility of multimodality therapies. In addition, the rarity of childhood brain tumors compared with adults' makes them more difficult to study. In this session, the following issues will be reviewed; 1. Incidence of pediatric brain tumors, 2. General issues regarding symptoms, diagnosis, diagnostic tests and evaluation, 3. Importance of a team approach, 4. General issues regarding treatment sequelae, 5. Specific tumor types/entities; a. Cerebellar Astrocytomas b. Benign and malignant Gliomas including brainstem and chiasmatic lesions c. Primitive Neuroectodermal Tumors (PNET) and Medulloblastoma d. Ependymomas e. Craniopharyngiomas f. Germ cell tumors g. Miscellaneous and rare pediatric brain tumors 6. Management of sequelae 7. New and future directions a. Treatment of infants b. The expanding role of chemotherapy c. Advances in radiotherapy. The attendees will complete the course with a better understanding of the role that radiation therapy plays in the treatment of pediatric brain tumors. They will be knowledgeable in the foundation for that role, and the changes which are likely to take place in the

  9. Current status of nuclear cardiology in Japan: Ongoing efforts to improve clinical standards and to establish evidence.

    Science.gov (United States)

    Yoshinaga, Keiichiro; Tamaki, Nagara

    2015-08-01

    Nuclear cardiology imaging tests are widely performed in Japan as clinical practice. The Japanese nuclear cardiology community has developed new diagnostic imaging tests using (123)I-beta-methyl-p-iodophenyl-pentadecanoic acid, (123)I-metaiodobenzylguanidine, and (18)F-fluorodeoxyglucose PET for detecting cardiac involvement in sarcoidosis. These tests have become popular worldwide. The Japanese Circulation Society and the Japanese Society of Nuclear Cardiology have published clinical imaging guidelines showing indications and standards for the new imaging tests. JSNC is currently striving to improve the standard of clinical practice and is promoting research activities.

  10. Calculation of Initial Short-Circuit Currents in Medium Voltage Networks According to the Standard PN-EN 60909

    Directory of Open Access Journals (Sweden)

    Krzysztof Księżyk

    2013-12-01

    Full Text Available Determining the short-circuit currents is usually conducted by network analyses. An important feature of this calculation is carried out according to the recommendations of the standard PN EN 60909. This paper describes the models of the basic elements of the network with the method of determining the impedance parameters including correction factors introduced by the standard. Thevenin’s method connected with the nodal method are presented and used to determine the initial short-circuit for the example medium voltage network. Results are compared with the ones obtained without taking into account the correction factors.

  11. Current considerations related to physiological differences between the sexes and physical employment standards.

    Science.gov (United States)

    Roberts, Delia; Gebhardt, Deborah L; Gaskill, Steven E; Roy, Tanja C; Sharp, Marilyn A

    2016-06-01

    The use of physical employment standards (PES) has helped ensure that workers have the physical attributes necessary to complete their jobs in a safe and efficient manner. However, PES used in the selection processes have not always reflected the critical physical requirements of the job tasks. Women generally have smaller anthropometric stature than men, less muscle mass, and therefore less strength, power, and endurance, particularly in the upper body. Nonetheless, these attributes in themselves are not valid grounds for exclusion from employment in physically demanding occupations. Selection standards based upon size or strength, irrespective of the job requirements, have resulted in the barring of capable women from physically demanding jobs, claims of gender bias, and costly litigations. To ensure all individuals are provided with equal access to employment, accurate characterization of the critical physical requirements of the job is paramount. This paper summarizes the existing research related to disparities between the sexes that contribute to sex differences in job performance in physically demanding occupations including physical and legal factors. Strategies for mitigating these differences in the setting of PES and the meeting of minimum employment standards are discussed. Where available, injury rates for women and men in physically demanding occupations are presented and the etiology considered. Finally, areas for further research are identified. PMID:27277561

  12. The Immunodominant Brugia malayi Paramyosin as a Marker of Current Infection with Wuchereria bancrofti Adult Worms

    OpenAIRE

    Langy, Sandra; Plichart, Catherine; Luquiaud, Patrick; Williams, Steven A.; Nicolas, Luc

    1998-01-01

    The full-length cDNA sequence encoding Brugia malayi L3 paramyosin has been isolated by immunoscreening a cDNA library with a mouse antiserum raised against Wuchereria bancrofti L3 infective larvae. A recombinant truncated form of paramyosin was expressed as a glutathione S-transferase fusion protein and used to evaluate humoral responses of adults from a W. bancrofti-endemic area in French Polynesia according to their parasitological status. Immunoglobulin G4 (IgG4) preferentially bound to p...

  13. Prehospital therapeutic hypothermia after cardiac arrest - from current concepts to a future standard

    OpenAIRE

    Hoppu Sanna; Kämäräinen Antti; Silfvast Tom; Virkkunen Ilkka

    2009-01-01

    Abstract Therapeutic hypothermia has been shown to improve survival and neurological outcome after prehospital cardiac arrest. Existing experimental and clinical evidence supports the notion that delayed cooling results in lesser benefit compared to early induction of mild hypothermia soon after return of spontaneous circulation. Therefore a practical approach would be to initiate cooling already in the prehospital setting. The purpose of this review was to evaluate current clinical studies o...

  14. The development and standardization of the Adult Developmental Co-ordination Disorders/Dyspraxia Checklist (ADC).

    Science.gov (United States)

    Kirby, Amanda; Edwards, Lisa; Sugden, David; Rosenblum, Sara

    2010-01-01

    Developmental Co-ordination Disorder (DCD), also known as Dyspraxia in the United Kingdom (U.K.), is a developmental disorder affecting motor co-ordination. In the past this was regarded as a childhood disorder, however there is increasing evidence that a significant number of children will continue to have persistent difficulties into adulthood. Despite this, there remains little information as to how the difficulties might present at this stage, and additionally the impact on every day functioning. As young people move into further and higher education there is a need for screening and assessment tools. Such tools allow for identification of these difficulties, access to support, and clarification of areas where appropriate support needs to be targeted. This paper describes the first adult screening tool for DCD. The development and the results from testing this tool in two countries, Israel and the U.K. are outlined and the implications for its use in further and higher education discussed. PMID:19819107

  15. Impact of parenteral nutrition standardization on costs and quality in adult patients

    Directory of Open Access Journals (Sweden)

    David Berlana

    2014-08-01

    Full Text Available Background: Parenteral nutrition (PN is a costly therapy that can also be associated with serious complications. Therefore, efforts are focusing on reducing rate of complications, and costs related to PN. Objective: The aim was to analyze the effect of the implementation of PN standardization on costs and quality criteria. Secondary aim was to assess the use of individualized PN based on patient's clinical condition. Methods: We compare the use of PN before and after the implementation of PN standardization. Demographic, clinical and PN characteristics were collected. Costs analysis was performed to study the costs associated to the two different periods. Quality criteria included were: 1 PN administration; 2 nutrition assessment (energy intake between 20-35 kcal/kg/day; protein contribution according to nitrogen balance; 3 safety and complications (hyperglycemia, hypertriglyceridemia, hepatic complications, catheter-related infection; 4 global efficacy (as serum albumin increase. Chi-square test was used to compare percentages; logistic regression analysis was performed to evaluate the use of customized PN. Results: 296 patients were included with a total of 3,167 PN compounded. During the first period standardized PN use was 47.5% vs 85.7% within the second period (p < 0.05. No differences were found in the quality criteria tested. Use of individualized PN was related to critical care patients, hypertriglyceridemia, renal damage, and long-term PN. Mean costs of the PN decreased a 19.5%. Annual costs savings would be € 86,700. Conclusions: The use of customized or standard PN has shown to be efficient and flexible to specific demands; however customized PN was significantly more expensive.

  16. Current data with inulin-type fructans and calcium, targeting bone health in adults.

    Science.gov (United States)

    Coxam, Véronique

    2007-11-01

    In humans, there is increasing evidence that the colon can absorb nutritionally significant amounts of calcium, and this process may be susceptible to dietary manipulation by fermentable substrates, especially inulin-type fructans. Inulin-type fructans can modulate calcium absorption because they are resistant to hydrolysis by mammalian enzymes and are fermented in the large intestine to produce short-chain fatty acids, which in turn reduce luminal pH and modify calcium speciation, and hence solubility, or exert a direct effect on the mucosal transport pathway. Quite a few intervention studies showed an improvement of calcium absorption in adolescents or young adults by inulin-type fructans. In the same way, a positive effect has been reported in older women.

  17. Effects of ionizing radiation on plants and animals at levels implied by current radiation protection standards

    International Nuclear Information System (INIS)

    The 1977 Recommendations of the International Commission on Radiological Protection stated that the commission believes that if man is adequately protected from radiation, other organisms are also likely to be sufficiently protected. The present report examines this statement by considering the effects of ionizing radiation on animals and plants in both terrestrial and aquatic ecosystems. The conclusions are that chronic dose rates of IMGy.d-1 or less are unlikely to cause measurable deleterious effects in terrestrial populations, and that in the aquatic environment limiting chronic dose rates to 10MGy.d-1 to the maximally exposed individuals would provide adequate protection for the population. Thus specific radiation protection standards for non-human organisms are not needed. 193 refs, 2 figs, 7 tabs

  18. Standardization of chemical analytical techniques for pyrolysis bio-oil: history, challenges, and current status of methods: Bio-oil Analytical Standardization

    Energy Technology Data Exchange (ETDEWEB)

    Ferrell, Jack R. [National Renewable Energy Laboratory (NREL), Golden CO USA; Olarte, Mariefel V. [Pacific Northwest National Laboratory (PNNL), Richland WA USA; Christensen, Earl D. [National Renewable Energy Laboratory (NREL), Golden CO USA; Padmaperuma, Asanga B. [Pacific Northwest National Laboratory (PNNL), Richland WA USA; Connatser, Raynella M. [Oak Ridge National Laboratory (ORNL), Oak Ridge TN USA; Stankovikj, Filip [Washington State University (WSU), Pullman WA USA; Meier, Dietrich [Thünen Institute of Wood Research (TI), Hamburg Germany; Paasikallio, Ville [VTT Technical Research Centre of Finland Ltd (VTT), Espoo Finland

    2016-07-05

    In this perspective, we discuss the standardization of analytical techniques for pyrolysis bio-oils, including the current status of methods, and our opinions on future directions. First, the history of past standardization efforts is summarized, and both successful and unsuccessful validation of analytical techniques highlighted. The majority of analytical standardization studies to-date has tested only physical characterization techniques. Here, we present results from an international round robin on the validation of chemical characterization techniques for bio-oils. Techniques tested included acid number, carbonyl titrations using two different methods (one at room temperature and one at 80 degrees C), 31P NMR for determination of hydroxyl groups, and a quantitative gas chromatography-mass spectrometry (GC-MS) method. Both carbonyl titration and acid number methods have yielded acceptable inter-laboratory variabilities. 31P NMR produced acceptable results for aliphatic and phenolic hydroxyl groups, but not for carboxylic hydroxyl groups. As shown in previous round robins, GC-MS results were more variable. Reliable chemical characterization of bio-oils will enable upgrading research and allow for detailed comparisons of bio-oils produced at different facilities. Reliable analytics are also needed to enable an emerging bioenergy industry, as processing facilities often have different analytical needs and capabilities than research facilities. We feel that correlations in reliable characterizations of bio-oils will help strike a balance between research and industry, and will ultimately help to determine metrics for bio-oil quality. Finally, the standardization of additional analytical methods is needed, particularly for upgraded bio-oils.

  19. Prehospital therapeutic hypothermia after cardiac arrest--from current concepts to a future standard.

    Science.gov (United States)

    Kämäräinen, Antti; Hoppu, Sanna; Silfvast, Tom; Virkkunen, Ilkka

    2009-01-01

    Therapeutic hypothermia has been shown to improve survival and neurological outcome after prehospital cardiac arrest. Existing experimental and clinical evidence supports the notion that delayed cooling results in lesser benefit compared to early induction of mild hypothermia soon after return of spontaneous circulation. Therefore a practical approach would be to initiate cooling already in the prehospital setting. The purpose of this review was to evaluate current clinical studies on prehospital induction of mild hypothermia after cardiac arrest. Most reported studies present data on cooling rates, safety and feasibility of different methods, but are inconclusive as regarding to outcome effects. PMID:19821967

  20. Prehospital therapeutic hypothermia after cardiac arrest - from current concepts to a future standard

    Directory of Open Access Journals (Sweden)

    Hoppu Sanna

    2009-10-01

    Full Text Available Abstract Therapeutic hypothermia has been shown to improve survival and neurological outcome after prehospital cardiac arrest. Existing experimental and clinical evidence supports the notion that delayed cooling results in lesser benefit compared to early induction of mild hypothermia soon after return of spontaneous circulation. Therefore a practical approach would be to initiate cooling already in the prehospital setting. The purpose of this review was to evaluate current clinical studies on prehospital induction of mild hypothermia after cardiac arrest. Most reported studies present data on cooling rates, safety and feasibility of different methods, but are inconclusive as regarding to outcome effects.

  1. Prehospital therapeutic hypothermia after cardiac arrest - from current concepts to a future standard

    Science.gov (United States)

    Kämäräinen, Antti; Hoppu, Sanna; Silfvast, Tom; Virkkunen, Ilkka

    2009-01-01

    Therapeutic hypothermia has been shown to improve survival and neurological outcome after prehospital cardiac arrest. Existing experimental and clinical evidence supports the notion that delayed cooling results in lesser benefit compared to early induction of mild hypothermia soon after return of spontaneous circulation. Therefore a practical approach would be to initiate cooling already in the prehospital setting. The purpose of this review was to evaluate current clinical studies on prehospital induction of mild hypothermia after cardiac arrest. Most reported studies present data on cooling rates, safety and feasibility of different methods, but are inconclusive as regarding to outcome effects. PMID:19821967

  2. Does SMS Text Messaging Help or Harm Adults' Knowledge of Standard Spelling?

    Science.gov (United States)

    Powell, D.; Dixon, M.

    2011-01-01

    The recent increase in short messaging system (SMS) text messaging, often using abbreviated, non-conventional "textisms" (e.g. "2nite"), in school-aged children has raised fears of negative consequences of such technology for literacy. The current research used a paradigm developed by Dixon and Kaminska, who showed that exposure to phonetically…

  3. Imaging in syndrome complex diabetes mellitus. Current standards and future perspectives

    International Nuclear Information System (INIS)

    Diabetes mellitus is a highly prevalent multisystemic disorder with numerous potential complications and substantial socioeconomic consequences. In many cases, the patient history, physical examination and laboratory tests are not sufficient for a comprehensive evaluation of complicating disorders. Imaging modalities, such as sonography, computed tomography (CT) and magnetic resonance imaging (MRI) are of major significance in the evaluation of complicating disorders of diabetes according to current guidelines. Examples include assessment of coronary artery disease, peripheral artery disease, stroke and diabetic foot syndrome. Technical developments allow a substantial reduction in radiation dose and scan time in CT and MRI, respectively and could therefore justify a broader application in this patient population. In the future CT and MRI could also be used for the early detection of diabetic complications. Furthermore, they could also be used for risk stratification, e.g. measurement of hepatic fat content and evaluation of atherosclerosis in whole body MRI. Prior to widespread application of advanced imaging techniques in this patient population, improved outcomes with respect to survival, quality of life and cost-effectiveness need to be demonstrated. Diagnostic imaging modalities for the evaluation of the syndrome complex of diabetic disorders should be used according to the current guidelines but the use is predicted to increase given the high potential in this population. (orig.)

  4. Numerically simulated cardiac exposure to electric current densities induced by TASER X-26 pulses in adult men

    Science.gov (United States)

    Leitgeb, N.; Niedermayr, F.; Neubauer, R.; Loos, G.

    2010-10-01

    There is still an ongoing debate whether or not electronic stun devices (ESDs) induce cardiac fibrillation. To assess the ventricular fibrillation risk of law enforcing electronic control devices, quantitative estimates of cardiac electric current densities induced by delivered electric pulses are essential. Numerical simulations were performed with the finite integration technique and the anatomical model of a standardized European man (NORMAN) segmented into 2 mm voxels and 35 different tissues. The load-dependent delivery of TASER X-26 pulses has been taken into account. Cardiac exposure to electric current densities of vertically and horizontally aligned dart electrodes was quantified and different hit scenarios compared. Since fibrillation thresholds critically depend on exposed volume, the provided quantitative data are essential for risk assessment. The maximum cardiac rms current densities amounted to 7730 A m-2. Such high current densities and exposed cardiac volumes do not exclude ventricular fibrillation.

  5. Numerically simulated cardiac exposure to electric current densities induced by TASER X-26 pulses in adult men

    International Nuclear Information System (INIS)

    There is still an ongoing debate whether or not electronic stun devices (ESDs) induce cardiac fibrillation. To assess the ventricular fibrillation risk of law enforcing electronic control devices, quantitative estimates of cardiac electric current densities induced by delivered electric pulses are essential. Numerical simulations were performed with the finite integration technique and the anatomical model of a standardized European man (NORMAN) segmented into 2 mm voxels and 35 different tissues. The load-dependent delivery of TASER X-26 pulses has been taken into account. Cardiac exposure to electric current densities of vertically and horizontally aligned dart electrodes was quantified and different hit scenarios compared. Since fibrillation thresholds critically depend on exposed volume, the provided quantitative data are essential for risk assessment. The maximum cardiac rms current densities amounted to 7730 A m-2. Such high current densities and exposed cardiac volumes do not exclude ventricular fibrillation.

  6. Numerically simulated cardiac exposure to electric current densities induced by TASER X-26 pulses in adult men

    Energy Technology Data Exchange (ETDEWEB)

    Leitgeb, N; Niedermayr, F; Neubauer, R; Loos, G, E-mail: norbert.leitgeb@tugraz.a [Institute of Clinical Engineering with European Notified Body of Medical Devices, Graz University of Technology, Inffeldgasse 18, A-8010 Graz (Austria)

    2010-10-21

    There is still an ongoing debate whether or not electronic stun devices (ESDs) induce cardiac fibrillation. To assess the ventricular fibrillation risk of law enforcing electronic control devices, quantitative estimates of cardiac electric current densities induced by delivered electric pulses are essential. Numerical simulations were performed with the finite integration technique and the anatomical model of a standardized European man (NORMAN) segmented into 2 mm voxels and 35 different tissues. The load-dependent delivery of TASER X-26 pulses has been taken into account. Cardiac exposure to electric current densities of vertically and horizontally aligned dart electrodes was quantified and different hit scenarios compared. Since fibrillation thresholds critically depend on exposed volume, the provided quantitative data are essential for risk assessment. The maximum cardiac rms current densities amounted to 7730 A m{sup -2}. Such high current densities and exposed cardiac volumes do not exclude ventricular fibrillation.

  7. Lifelong Education for Older Adults in Malta: Current Trends and Future Visions

    Science.gov (United States)

    Formosa, Marvin

    2012-01-01

    With European demographic developments causing a decline of the available workforce in the foreseeable future and the unsustainability of dominant pay-as-you-go pension systems (where contributions from the current workforce sustain pensioners), governments need to come up with strategies to deal with this upcoming challenge and to adjust their…

  8. Current Situation and Development Trend of Standards of Lithium Batteries for Electric Vehides

    Institute of Scientific and Technical Information of China (English)

    Meng Xiangfeng; Wen Baozhong

    2012-01-01

    Traction battery is one of the most significant systems in electric vehicles.Its general performance,cycle characteristics and safety performance have crucial influence on the economical efficiency,dynamic property and safety of the vehicle.Therefore traction battery has always been the key area in researches of electric vehicles and its standardization. 1.Main performance indicators of traction batteries As the energy storage device of electric vehicles,the performance of traction battery is very important for the complete vehicle.Requirements of traction battery for electric vehicles should have the following characteristics as high power,high energy,high energy density/specific energy,high power density/specific power,low cost,long life length,abuse resistance,high reliability,good temperature property,short charging time,nice interchangeability etc.Traction batteries used at present are mainly lead-acid cells,nickel-hydride cells and lithium-ion cells.Although none of them can meet all requirements,lithium battery is widely regarded the most promising one with optimal comprehensive performance in recent time.

  9. Limiting the costs of renewable portfolio standards: A review and critique of current methods

    International Nuclear Information System (INIS)

    Over half of U.S. states have renewable portfolio standards (RPSs) mandating that a minimum percentage of electricity sold derives from renewable sources. State RPSs vary widely in how they attempt to control or limit the costs of these RPSs. Approaches utilized include alternative compliance payments, direct rate caps, and cost caps on resource acquisitions, while some states employ no specific limitation at all. This paper describes how states attempt to control RPS costs and discusses the strengths and weaknesses of these various cost controls. There is no one best method; however the experience to date suggests that the most important factors in implementing an effective mechanism to curtail costs are clarity of the rule, consistency in application, and transparency for customers. - Highlights: ▶ We review states' RPS statutes and regulations for mechanisms that attempt to control overall compliance costs. ▶ We categorize the major cost curtailment mechanisms. ▶ For each mechanism, we describe policy designs that are or could be implemented by states. ▶ We identify strengths and weaknesses of the various designs for consideration by policymakers.

  10. A review of standard pharmacological therapy for adult asthma – Steps 1 to 5.

    Science.gov (United States)

    Patel, Mitesh; Shaw, Dominick

    2015-05-01

    The aim of pharmacological therapy for asthma is to improve symptoms and lung function and minimize the risk of asthma attacks. The intensity of treatment is based on the level of asthma control and the potential risk of future deterioration. In the British asthma guidelines, treatments are divided into steps 1 to 5, with each step signifying a need for an increase in therapy in response to symptoms or to prevent exacerbations. Treatments comprise of inhaled or systemic medications. Inhaled therapy includes short-acting and long-acting medication to improve symptoms and inhaled corticosteroids that reduce airway inflammation. Systemic treatments include medications that act on specific biological pathways, such as the leukotriene or immunoglobulin E pathways, or systemic corticosteroids. In choosing a particular therapy, treatment benefits are balanced by the potential risks of medication-related adverse effects. This review will provide a practical guide to the key pharmacological therapies for adult asthma at steps 1 to 5 based on British guidelines and consider future options for new treatments.

  11. Ethical problems with the mental health evaluation standards of care for adult gender variant prospective patients.

    Science.gov (United States)

    Hale, C Jabob

    2007-01-01

    The World Professional Association for Transgender Health's "Standards of Care: The Hormonal and Surgical Sex Reassignment of Gender Dysphoric Persons" (SOC) set forth standards clinicians must meet to ensure ethical care of adequate quality. The SOC also set requirements gender variant prospective patients must meet to receive medical interventions to change their sexual characteristics to those more typical for the sex to which they were not assigned at birth. One such requirement is that mental health professionals must ascertain that prospective patients have met the SOC's eligibility and readiness criteria. This article raises two objections to this requirement: ethically obligatory considerations of the overall balance of potential harms and benefits tell against it, and it violates the principle of respect for autonomy. This requirement treats gender variant prospective patients who request medical intervention as different in kind, not merely degree, from other patient populations, as it constructs the very request as a phenomenon of incapacity. This is ethically indefensible in and of itself, but it is especially pernicious in a sociocultural and political context that already denies gender variant people full moral status. PMID:17951884

  12. Current Trends in the Monitoring and Treatment of Diabetic Retinopathy in Young Adults

    Directory of Open Access Journals (Sweden)

    Dorota Raczyńska

    2014-01-01

    Full Text Available The diagnosis and treatment of diabetic retinopathy (DR in young adults have significantly improved in recent years. Research methods have widened significantly, for example, by introducing spectral optical tomography of the eye. Invasive diagnostics, for example, fluorescein angiography, are done less frequently. The early introduction of an insulin pump to improve the administration of insulin is likely to delay the development of diabetic retinopathy, which is particularly important for young patients with type 1 diabetes mellitus (T1DM. The first years of diabetes occurring during childhood and youth are the most appropriate to introduce proper therapeutic intervention before any irreversible changes in the eyes appear. The treatment of DR includes increased metabolic control, laserotherapy, pharmacological treatment (antiangiogenic and anti-inflammatory treatment, enzymatic vitreolysis, and intravitreal injections, and surgery. This paper summarizes the up-to-date developments in the diagnostics and treatment of DR. In the literature search, authors used online databases, PubMed, and clinitrials.gov and browsed through individual ophthalmology journals, books, and leading pharmaceutical company websites.

  13. Radiotherapy in the management of non-metastatic prostate cancer: Current standards and future opportunities

    International Nuclear Information System (INIS)

    Objectives: The intent of this course is to review issues involved in the management of non-metastatic prostate cancer and to clarify the role of external beam radiotherapy, the use of neo-adjuvant and adjuvant hormonal therapy in conjunction with the radiation, the management of patients with regional metastases and recurrent disease following surgery and radiation. At the end of this course, participants should be able to fluently discuss management issues and strategies across the entire spectrum of non-metastatic prostate cancer. - Pre-treatment prognostic factors including clinical stage, grade, and pre-treatment PSA, will be presented and their relative value in determining therapeutic strategies will be discussed. Strategies to be discussed include standard dose radiation, escalated dose radiation, particle radiation and the use of adjuvant and neo-adjuvant hormonal therapy. - The process of simulation and field design will be presented, the value of CT-based treatment planning, beams-eye view design and the relative value of three-dimensional treatment planning will be discussed. - The significance of prostate and patient movement and strategies for dealing with this will also be presented so that what constitutes an adequate simulation and margin of treatment can be clarified. - The management of newly diagnosed patients, covering the range of low stage/low grade to locally advanced prostate cancer will be discussed. - The relative value of increasing dose, the relative value of using neo-adjuvant and/or adjuvant hormone therapy and the indications for escalated dose will be presented. - Strategies for managing post-prostatectomy patients will be reviewed. Data on adjuvant and therapeutic irradiation for biochemical failure will be presented and a strategy for management will be discussed. - How to deal with patients with residual disease post radiation will be discussed and the relative value of cryotherapy, salvage prostatectomy or hormonal therapy will

  14. Sarcopenia: An Undiagnosed Condition in Older Adults. Current Consensus Definition: Prevalence, Etiology, and Consequences

    OpenAIRE

    2011-01-01

    Sarcopenia, the age associated loss of skeletal muscle mass and function, has considerable societal consequences for the development of frailty, disability and health care planning. A group of geriatricians and scientists from academia and industry met in Rome, Italy on November 18, 2009 to arrive at a consensus definition of sarcopenia. The current consensus definition was approved unanimously by the meeting participants and is as follows: Sarcopenia is defined as the age-associated loss of ...

  15. A Summary of Proposed Changes to the Current ICARTT Format Standards and their Implications to Future Airborne Studies

    Science.gov (United States)

    Northup, E. A.; Kusterer, J.; Quam, B.; Chen, G.; Early, A. B.; Beach, A. L., III

    2015-12-01

    The current ICARTT file format standards were developed for the purpose of fulfilling the data management needs for the International Consortium for Atmospheric Research on Transport and Transformation (ICARTT) campaign in 2004. The goal of the ICARTT file format was to establish a common and simple to use data file format to promote data exchange and collaboration among science teams with similar science objectives. ICARTT has been the NASA standard since 2010, and is widely used by NOAA, NSF, and international partners (DLR, FAAM). Despite its level of acceptance, there are a number of issues with the current ICARTT format, especially concerning the machine readability. To enhance usability, the ICARTT Refresh Earth Science Data Systems Working Group (ESDSWG) was established to enable a platform for atmospheric science data producers, users (e.g. modelers) and data managers to collaborate on developing criteria for this file format. Ultimately, this is a cross agency effort to improve and aggregate the metadata records being produced. After conducting a survey to identify deficiencies in the current format, we determined which are considered most important to the various communities. Numerous recommendations were made to improve upon the file format while maintaining backward compatibility. The recommendations made to date and their advantages and limitations will be discussed.

  16. [Digital Game Addiction Among Adolescents and Younger Adults: A Current Overview].

    Science.gov (United States)

    Yalçın Irmak, Aylin; Erdoğan, Semra

    2016-01-01

    The games that adolescents and young people used to play in the play grounds and on the streets have been replaced in recent years with cyber games played in front of the computer on the internet or in game arcades. This changing culture has particularly brought up the concept of "digital game addiction", a condition that stems from the steadily growing passion for digital games and their excessived and uncontrolled usage among adolescents and young people. Game addiction in the psychiatry literature has been described as an impulse control disorder characterized by the symptoms such as "the inability to control the time spent on game-playing", "a loss of interest in other activities", "continuing to play despite the adverse effects" and "feeling psychologically deprived when not being able to play"."Although digital game addiction has not been accepted by psychiatric authorities as a psychiatric disorder yet, the increasing psychiatry referrals due to the problems accompanying this disorder, the efforts of families to seek support and solutions, the evidence that similarities with other types of addiction have been revealed by researchers, as well as the current prevalence rates are all factors that suggest the existence of important of the examination of issue. Despite the discussions about the digital game addiction, the literature on the subject is increasing. This article offers an overview of digital game-playing behavior in the light of current literature, seeking to share its findings with health care professionals.

  17. [Digital Game Addiction Among Adolescents and Younger Adults: A Current Overview].

    Science.gov (United States)

    Yalçın Irmak, Aylin; Erdoğan, Semra

    2016-01-01

    The games that adolescents and young people used to play in the play grounds and on the streets have been replaced in recent years with cyber games played in front of the computer on the internet or in game arcades. This changing culture has particularly brought up the concept of "digital game addiction", a condition that stems from the steadily growing passion for digital games and their excessived and uncontrolled usage among adolescents and young people. Game addiction in the psychiatry literature has been described as an impulse control disorder characterized by the symptoms such as "the inability to control the time spent on game-playing", "a loss of interest in other activities", "continuing to play despite the adverse effects" and "feeling psychologically deprived when not being able to play"."Although digital game addiction has not been accepted by psychiatric authorities as a psychiatric disorder yet, the increasing psychiatry referrals due to the problems accompanying this disorder, the efforts of families to seek support and solutions, the evidence that similarities with other types of addiction have been revealed by researchers, as well as the current prevalence rates are all factors that suggest the existence of important of the examination of issue. Despite the discussions about the digital game addiction, the literature on the subject is increasing. This article offers an overview of digital game-playing behavior in the light of current literature, seeking to share its findings with health care professionals. PMID:27370064

  18. Fatty acid and vitamin interventions in adults with schizophrenia: a systematic review of the current evidence.

    Science.gov (United States)

    Chia, Siok Ching; Henry, Jeyakumar; Mok, Yee Ming; Honer, William G; Sim, Kang

    2015-12-01

    Current psychopharmacological approaches to reduce psychotic phenomenology in schizophrenia are associated with adverse effects including extrapyramidal and metabolic side effects. In view of the emerging data on nutritional supplementation interventions in schizophrenia which are not entirely consistent, we aimed to review existent studies focusing on fatty acid and vitamin interventions and summarise current evidence on such nutritional supplementations in schizophrenia. We searched the digital databases (ScienceDirect, Scopus, SpringerLINK, PubMed/Medline) for relevant studies pertaining to fatty acid and vitamin supplementation interventions in the management of psychotic symptoms in schizophrenia up to February 2015. Overall, there were more studies conducted on fatty acid over vitamin supplementations in patients with schizophrenia. There were more positive findings in support of fatty acid supplementation compared with vitamin supplementation in the context of specific intervention features (dose of nutrient supplementation, single versus combination nutritional interventions, specific antipsychotic), subject features (older age, long duration of illness, baseline polyunsaturated fatty acid levels) and clinical outcomes (improvements of psychotic symptoms and/or extrapyramidal side effects from antipsychotics). However, investigations of both supplementation modalities were limited by relatively small study sample sizes, short study duration, which precluded further segmentation of impact on more diverse patient subtypes and symptom profiles. Future studies may consider examining larger samples over a longer time period, recruiting younger subjects with shorter duration of illness, examination of different clinical features including specific cognitive domains, and use of single versus combination nutritional interventions. PMID:26354100

  19. Fatty acid and vitamin interventions in adults with schizophrenia: a systematic review of the current evidence.

    Science.gov (United States)

    Chia, Siok Ching; Henry, Jeyakumar; Mok, Yee Ming; Honer, William G; Sim, Kang

    2015-12-01

    Current psychopharmacological approaches to reduce psychotic phenomenology in schizophrenia are associated with adverse effects including extrapyramidal and metabolic side effects. In view of the emerging data on nutritional supplementation interventions in schizophrenia which are not entirely consistent, we aimed to review existent studies focusing on fatty acid and vitamin interventions and summarise current evidence on such nutritional supplementations in schizophrenia. We searched the digital databases (ScienceDirect, Scopus, SpringerLINK, PubMed/Medline) for relevant studies pertaining to fatty acid and vitamin supplementation interventions in the management of psychotic symptoms in schizophrenia up to February 2015. Overall, there were more studies conducted on fatty acid over vitamin supplementations in patients with schizophrenia. There were more positive findings in support of fatty acid supplementation compared with vitamin supplementation in the context of specific intervention features (dose of nutrient supplementation, single versus combination nutritional interventions, specific antipsychotic), subject features (older age, long duration of illness, baseline polyunsaturated fatty acid levels) and clinical outcomes (improvements of psychotic symptoms and/or extrapyramidal side effects from antipsychotics). However, investigations of both supplementation modalities were limited by relatively small study sample sizes, short study duration, which precluded further segmentation of impact on more diverse patient subtypes and symptom profiles. Future studies may consider examining larger samples over a longer time period, recruiting younger subjects with shorter duration of illness, examination of different clinical features including specific cognitive domains, and use of single versus combination nutritional interventions.

  20. Aseptic osteonecrosis of the hip in the adult: current evidence on conservative treatment.

    Science.gov (United States)

    Klumpp, Raymond; Trevisan, Carlo

    2015-01-01

    Treatment of Avascular Osteonecrosis (AVN) of the femoral head to prevent progression to an arthritic hip is a challenging subject. Many conservative treatment options have been proposed in the literature. Weight bearing restriction as a stand-alone therapy is insufficient in preventing disease progression but it may be useful when combined with pharmacological agents or surgery. Bisphosphonate treatment in AVN might be efficient in early stages of disease, however there are no clear recommendations on length of treatment and therapeutic dosage and, considered the limited evidence and potential side effects of treatment, it could be considered in a pre-collapse stage in selected cases. Current literature suggests that low molecular weight heparin could lower disease progression in idiopathic AVN with quality of evidence being very low. Also the evidence to support the use of statins or vasodilators in the treatment of osteonecrosis is very low and their use cannot be recommended. Extracorporeal shock wave therapy may improve pain and function in early stages of disease with a low evidence, but there doesn't seem to be a significant change in time to the occurrence of femoral head collapse. Only one study has been conducted with pulsed electromagnetic fields therefore no recommendation can be given on clinical use of PEF in AVN. Evidence on hyperbaric oxygen therapy in the treatment of AVN is very limited and the high cost of treatment and the limited availability of structures that can provide the service poses other concerns about its feasibility. Based on current evidence, conservative treatment may be considered in early stages of asymptomatic AVN instead of observation only. PMID:27134631

  1. [Nutritional status of adults with cystic fibrosis - current methods of assessment].

    Science.gov (United States)

    Szabla, Anna; Skorupa, Wojciech; Milewska, Magdalena; Weker, Halina

    2015-11-01

    Cystic fibrosis (CF) is one of the most frequent monogenic disease in the Caucasian population, inherited in an autosomal recessive pattern. This is a multiple organ disease and its main manifestations include pulmonary and gastrointestinal dysfunction. The exocrine pancreatic deficiency results in impaired digestion and absorption what may lead to malnutrition and vitamins and minerals deficiencies. The life expectancy of cystic fibrosis patients has been increasing over the past years, so there is a need to verify usefulness of existing or create new methods of nutritional status assessment. The aim of this paper was presentation current data on the methods of assessment and monitoring of nutritional status. Particular attention has been paid to appropriate nutritional support in prevention and treatment of malnutrition patients with cystic fibrosis. On the basis of recent literature we can conclude that the advanced nutritional status assessment is recommended in patient with CF by using anthropometrical methods, body composition analysis and biochemical data. Good nutritional status is connected with pulmonary functions, quality and life length.

  2. A review of current and future treatment strategies for malignant astrocytomas in adults

    Energy Technology Data Exchange (ETDEWEB)

    Nieder, C. [Texas Univ., Houston, TX (United States). Dept. of Experimental Radiation Oncology; Nestle, U. [Universitaet des Saarlandes, Homburg/Saar (Germany). Radiologische Klinik

    2000-06-01

    This review discusses available laboratory and clinical data as well as recent advances in our knowledge about prognostic factors and their implications for the design of future clinical trials. Results: Elucidation of the biology of malignant astrocytomas allowed for development of rational new approaches, such as gene therapy and immunotherapy, which could interfere with established treatment regimens or being used independently. Possible strategies include the restoration of defective cancer-inhibitory genes, cell transduction or transfection with antisense DNA corresponding to genes coding for growth factors and their receptors, or with the so-called suicide genes. Several antiangiogenic approaches such as administration of thalidomide, protamine, or monoclonal antibodies against vascular endothelial growth factor have been developed, too. Further treatment possibilities include modulation of drug resistance, e.g. by P-glycoprotein antagonists or O6-alkyl-guanine-DNA-transferase inhibitors, inhibition of matrix metalloproteinases, inhibition of protein kinase C, and administration of agents such as phenylbutyrate or valproic acid that showed promising antiproliferative effects in vitro. Conclusions: Several rational new approaches are now entering clinical trials. In the light of limited survival after standard treatment it is recommended that patients should be offered participation in such trials. (orig.) [German] In dieser Arbeit werden sowohl die verfuegbaren Labor- und klinischen Daten als auch die aktuellen Fortschritte auf dem Gebiet prognostischer Faktoren und deren Bedeutung fuer das Design kuenftiger klinischer Studien diskutiert. Ergebnisse: Die Aufklaerung der Biologie dieser Tumoren ermoeglichte die Entwicklung rationaler neuer Strategien, zum Beispiel basierend auf der Gen- und Immuntherapie, die entweder zusammen mit etablierten Methoden oder allein anwendbar sind. Moegliche Strategien bestehen in der Wiederherstellung defekter

  3. Upgrade of the ESA DRAMA OSCAR Tool: Analysis of Disposal Strategies Considering Current Standards for Future Solar and Geomagnetic Activity

    Science.gov (United States)

    Braun, V.; Sanchez-Ortiz, N.; Gelhaus, J.; Kebschull, C.; Flegel, S.; Mockel, M.; Wiedemann, C.; Krag, H.; Vorsmann, P.

    2013-08-01

    In 2008 the UN General Assembly adopted resolution 62/217, endorsing the space debris mitigation guidelines (SDMG) of the UN Committee on the Peaceful Uses of Outer Space (UNCOPUOS). These guidelines contain recommendations for satellite operators to implement measures for various mission phases in order to reduce the further accumulation of space debris in space and especially within the protected regions. These are defined within the SDMG as being the LEO region (up to 2,000 km altitude) and the GEO region (∼200 km in altitude around the GEO altitude and ∼15 degrees latitude). In the first version of ESA's DRAMA tool suite, OSCAR (Orbital SpaceCraft Active Removal) was designed as a tool to allow users the analysis of different disposal stragies for spacecraft in the LEO and GEO region. The upgrade of the ESA DRAMA tool suite by TUBS and DEIMOS under ESA/ESOC contract included the development of a renewed version of the existing OSCAR tool, allowing in its current version the consideration of different future solar and geomagnetic activity scenarios and besides the already known disposal systems (chemical and electric propulsion, as well as electrodynamic tether) the analysis of the orbital evolution using drag augmentation devices. One of the primary goals was to implement techniques recommended by current standards. The recommendations from the SDMG were used for the definition of the critical regions as well as compliance criteria, the user may check his disposal strategy against. For satellites operating in GEO, the ISO 26872:2010 (Space Systems - Disposal of satellites operating at geosynchronous altitude) standard was accounted for. For the generation of future solar and geomagnetic activity, the standards ISO 27852:2011 (Space Systems -Estimation of orbit lifetime) and the ECSS-E-ST-10-04C (Space engineering - Space environment) have been considered and recommended modeling approaches were implemented. In this paper, the OSCAR tool is presented, giving

  4. RT-PCR standardization and bone mineralization after low-level laser therapy on adult osteoblast cells

    Science.gov (United States)

    do Bomfim, Fernando R. C.; Sella, Valéria R. G.; Zanaga, Jéssica Q.; Pereira, Nayara S.; Nouailhetas, Viviane L. A.; Plapler, Hélio

    2014-03-01

    Purpose: Osteoblasts are capable to produce different compounds directly connected to bone mineralization process. This study aims to standardize the reverse transcriptase polymerase chain reaction (RT-PCR) for adult osteoblasts to observe the effect of low level laser therapy on bone mineralization. Methods: Five-millimeter long fragments obtained from the mead femoral region of male Wistar rats were assigned into group A (n=10, laser) and group B (n=10, no laser), submitted to mechanic and enzymatic digestion. After 7 days, cultures of group A were irradiated daily on a single spot with a GaInAs laser, λ=808nm, 200mW/cm2, 2J/cm2, bean diameter of 0,02mm, 5 seconds for 6 days. Group B was manipulated but received no laser irradiation. After 13 days the cells were trypsinized for 15 minute and stabilized with RNA later® for RNA extraction with Trizol®. cDNA synthesis used 10μg of RNA and M-MLV® enzyme. PCR was accomplished using the β-actin gene as a control. Another aliquot was fixed for Hematoxylin-Eosin and Von Kossa staining to visualize bone mineralization areas. Results: Under UV light we observed clearly the amplification of β-actin gene around 400bp. HE and Von Kossa staining showed osteoblast clusters, a higher number of bone cells and well defined mineralization areas in group A. Conclusion: The cell culture, RNA extraction and RT-PCR method for adult osteoblasts was effective, allowing to use these methods for bone mineralization studies. Laser improved bone mineralization and further studies are needed involving osteogenesis, calcium release mechanisms and calcium related channels.

  5. Ambulatory Blood Pressure Monitoring (ABPM) as the reference standard for diagnosis of hypertension and assessment of vascular risk in adults.

    Science.gov (United States)

    Hermida, Ramón C; Smolensky, Michael H; Ayala, Diana E; Portaluppi, Francesco

    2015-01-01

    New information has become available since the ISC, AAMCC, and SECAC released their first extensive guidedelines to improve the diagnosis and treatment of adult arterial hypertension. A critical assessment of evidence and a comparison of what international guidelines now propose are the basis for the following statements, which update the recommendations first issued in 2013. Office blood pressure (BP) measurements should no longer be considered to be the "gold standard" for the diagnosis of hypertension and assessment of cardiovascular risk. Relying on office BP, even when supplemented with at-home wake-time self-measurements, to identify high-risk individuals, disregarding circadian BP patterning and asleep BP level, leads to potential misclassification of 50% of all evaluated persons. Accordingly, ambulatory BP monitoring is the recommended reference standard for the diagnosis of true hypertension and accurate assessment of cardiovascular risk in all adults ≥18 yrs of age, regardless of whether office BP is normal or elevated. Asleep systolic BP mean is the most significant independent predictor of cardiovascular events. The sleep-time relative SBP decline adds prognostic value to the statistical model that already includes the asleep systolic BP mean and corrected for relevant confounding variables. Accordingly, the asleep systolic BP mean is the recommended protocol to diagnose hypertension, assess cardiovascular risk, and predict cardiovascular event-free interval. In men, and in the absence of compelling clinical conditions, reference thresholds for diagnosing hypertension are 120/70 mmHg for the asleep systolic/diastolic BP means derived from ambulatory BP monitoring. However, in women, in the absence of complicating co-morbidities, the same thresholds are lower by 10/5 mmHg, i.e., 110/65 mmHg for the asleep means. In high-risk patients, including those diagnosed with diabetes or chronic kidney disease, and/or those having experienced past

  6. Prevalence of Diagnosed Cancer According to Duration of Diagnosed Diabetes and Current Insulin Use Among U.S. Adults With Diagnosed Diabetes

    OpenAIRE

    Li, Chaoyang; Zhao, Guixiang; Okoro, Catherine A; Wen, Xiao-Jun; Ford, Earl S.; Balluz, Lina S

    2013-01-01

    OBJECTIVE To estimate the prevalence of diagnosed cancer according to duration of diagnosed diabetes and current insulin use among U.S. adults with diagnosed diabetes. RESEARCH DESIGN AND METHODS We analyzed data from 25,964 adults aged ≥18 years with diagnosed diabetes who participated in the 2009 Behavioral Risk Factor Surveillance System. RESULTS After adjustment for potential confounders, we found that the greater the duration of diagnosed diabetes, the higher the prevalence of diagnosed ...

  7. Making Sense of Varying Standards of Care: The Experiences of Staff Working in Residential Care Environments for Adults with Learning Disabilities

    Science.gov (United States)

    Hutchison, Andrew; Kroese, Biza Stenfert

    2016-01-01

    Research evidence reveals that adults with learning disabilities who live in residential care facilities are being exposed to considerable variation in the standards of care they receive. High profile cases of substandard care have also raised concerns regarding the appropriateness of existing care provisions and practices. While attempts have…

  8. Screening for Diabetic Retinopathy in Adults with Learning Disability: Current Uptake and Adjustments to Facilitate Equality of Access

    Science.gov (United States)

    Pilling, Rachel F.

    2015-01-01

    Equality of access to health care for adults with learning disability has been in the spotlight in the UK in recent years due to publication of several reports. Adults with learning disability are thought to account for a significant proportion of the diabetic population in the UK. A list of adults known to the learning disability health…

  9. Are the dental health needs of adults with illegal drug dependence being met by current service provision in the United Kingdom?: a literature review.

    Science.gov (United States)

    Hewson, Victoria; Wray, Jane

    2012-10-01

    This literature review outlines the current issues and debates relating to the dental health of adults with drug dependence. The dental health of adults with illegal drug dependence (IDD) continues to be under debate throughout dental practice, and the most appropriate model of care suitable to meet the high complex needs of this client group remains uncertain. The study aims to review and critically analyze available research relating to the oral health effects of illegal drug misuse and the dental health needs and status of adults with drug dependence. Second, it aims to identify and critically evaluate current models of dental service/care delivery, including relevant best practice guidance and potential barriers to dental access for adults with IDD. The available literature pertaining to dental health and adults with drug dependence are systematically reviewed and critically analyzed and evaluated in order to execute a rigorous investigation. The oral effects along with general medical complications associated with IDD are increasingly being recognized. There are substantive negative effects of IDD on oral health, particularly for those with opioid dependence; therefore, these clients have high complex dental needs and low use of dental services. Adults with drug dependence comprise a group with special dental needs and therefore need greater access to dental care than most people due to their high level of need. A high awareness of the implications for oral health care for adults with drug dependence is essential. Dental professionals have a key role in supporting the rehabilitation of these patients from potentially severe or fatal addictions. There is a distinct lack of national policy and guidance relating specifically to adults with drug dependence, and therefore, problems persist. Key findings and recommendations are presented to enhance the development of dental services for adults with IDD.

  10. Associations between a History of Traumatic Brain Injuries and Current Cigarette Smoking, Substance Use, and Elevated Psychological Distress in a Population Sample of Canadian Adults.

    Science.gov (United States)

    Ilie, Gabriela; Adlaf, Edward M; Mann, Robert E; Ialomiteanu, Anca; Hamilton, Hayley; Rehm, Jürgen; Asbridge, Mark; Cusimano, Michael D

    2015-07-15

    This study describes the prevalence of reported history of traumatic brain injury (TBI) and its association with reports of current substance use, cigarette smoking, and psychological distress among Canadian adults in a population sample. A cross-sectional sample of 1999 Ontario adults 18-93 years of age were surveyed by telephone in 2011 as part of the Center for Addiction and Mental Health's ongoing representative survey of adult mental health and substance use in Ontario, Canada. Loss of consciousness for at least 5 min or at least one overnight hospitalization resulting from symptoms associated with the TBI injury represented minimum criteria for TBI. An estimated 16.8% (95% confidence interval, 14.8, 19.0) of adults reported a TBI in their lifetime. Men had higher prevalence of TBI than women. Adults who reported a history of TBI had higher odds of reported past-year daily smoking (adjusted odds ratio [AOR] = 2.15), using cannabis (AOR = 2.80) and nonmedical opioids (AOR = 2.90), as well as screened significantly for recent elevated psychological distress (AOR = 1.97) in the past few weeks, compared to adults without a history of TBI. Co-occurrence of a history of TBI with current elevated psychological distress and substance use warrants vigilance among medical practitioners to assess the possibility of a history of TBI during reviews of the history leading to the occurrence of these conditions.

  11. Associations between a History of Traumatic Brain Injuries and Current Cigarette Smoking, Substance Use, and Elevated Psychological Distress in a Population Sample of Canadian Adults.

    Science.gov (United States)

    Ilie, Gabriela; Adlaf, Edward M; Mann, Robert E; Ialomiteanu, Anca; Hamilton, Hayley; Rehm, Jürgen; Asbridge, Mark; Cusimano, Michael D

    2015-07-15

    This study describes the prevalence of reported history of traumatic brain injury (TBI) and its association with reports of current substance use, cigarette smoking, and psychological distress among Canadian adults in a population sample. A cross-sectional sample of 1999 Ontario adults 18-93 years of age were surveyed by telephone in 2011 as part of the Center for Addiction and Mental Health's ongoing representative survey of adult mental health and substance use in Ontario, Canada. Loss of consciousness for at least 5 min or at least one overnight hospitalization resulting from symptoms associated with the TBI injury represented minimum criteria for TBI. An estimated 16.8% (95% confidence interval, 14.8, 19.0) of adults reported a TBI in their lifetime. Men had higher prevalence of TBI than women. Adults who reported a history of TBI had higher odds of reported past-year daily smoking (adjusted odds ratio [AOR] = 2.15), using cannabis (AOR = 2.80) and nonmedical opioids (AOR = 2.90), as well as screened significantly for recent elevated psychological distress (AOR = 1.97) in the past few weeks, compared to adults without a history of TBI. Co-occurrence of a history of TBI with current elevated psychological distress and substance use warrants vigilance among medical practitioners to assess the possibility of a history of TBI during reviews of the history leading to the occurrence of these conditions. PMID:25496189

  12. Dietary intake and nutritional status of micronutrients in adults with cystic fibrosis in relation to current recommendations.

    Science.gov (United States)

    Li, Li; Somerset, Shawn

    2016-08-01

    An increased prevalence of cystic fibrosis (CF) related complications such as impaired bone health and diabetes has accompanied increased survival of patients with CF. This review was conducted to determine the extent to which adults with CF are meeting current nutrition recommendations for micronutrients in association with CF-related complications management. Although dietary intake and nutritional status in CF has improved significantly in recent decades, micronutrient status seems to have diverged. While vitamin A and E intakes appear adequate, frequent vitamin D and K deficiency/insufficiency and compromised bone health in CF, occurs despite supplementation. Although deficiency of water-soluble vitamins and minerals is uncommon, ongoing surveillance will enhance overall health outcomes, particularly in cases of CF-related liver disease and deteriorated lung function and bone health. Salt and fluid status in CF may also need attention due to diminished thirst sensation and voluntary rehydration. Further investigation in micronutrient status optimisation in CF will inform the development of more effective and targeted nutrition therapies to enable integration of more refined recommendations for micronutrient intakes in CF based on individual needs and disease progression.

  13. Dietary intake and nutritional status of micronutrients in adults with cystic fibrosis in relation to current recommendations.

    Science.gov (United States)

    Li, Li; Somerset, Shawn

    2016-08-01

    An increased prevalence of cystic fibrosis (CF) related complications such as impaired bone health and diabetes has accompanied increased survival of patients with CF. This review was conducted to determine the extent to which adults with CF are meeting current nutrition recommendations for micronutrients in association with CF-related complications management. Although dietary intake and nutritional status in CF has improved significantly in recent decades, micronutrient status seems to have diverged. While vitamin A and E intakes appear adequate, frequent vitamin D and K deficiency/insufficiency and compromised bone health in CF, occurs despite supplementation. Although deficiency of water-soluble vitamins and minerals is uncommon, ongoing surveillance will enhance overall health outcomes, particularly in cases of CF-related liver disease and deteriorated lung function and bone health. Salt and fluid status in CF may also need attention due to diminished thirst sensation and voluntary rehydration. Further investigation in micronutrient status optimisation in CF will inform the development of more effective and targeted nutrition therapies to enable integration of more refined recommendations for micronutrient intakes in CF based on individual needs and disease progression. PMID:26159903

  14. Cost-effectiveness analysis of sofosbuvir compared to current standard treatment in Swiss patients with chronic hepatitis C.

    Directory of Open Access Journals (Sweden)

    Alena M Pfeil

    Full Text Available In clinical trials, sofosbuvir showed high antiviral activity in patients infected with hepatitis C virus (HCV across all genotypes. We aimed to determine the cost-effectiveness of sofosbuvir-based treatment compared to current standard treatment in mono-infected patients with chronic hepatitis C (CHC genotypes 1-4 in Switzerland. Cost-effectiveness was modelled from the perspective of the Swiss health care system using a lifetime Markov model. Incremental cost-effectiveness ratios (ICERs used an endpoint of cost per quality-adjusted life year (QALY gained. Treatment characteristics, quality of life, and transition probabilities were obtained from published literature. Country-specific model inputs such as patient characteristics, mortality and costs were obtained from Swiss sources. We performed extensive sensitivity analyses. Costs and effects were discounted at 3% (range: 0-5% per year. Sofosbuvir-containing treatment in mixed cohorts of cirrhotic and non-cirrhotic patients with CHC genotypes 1-4 showed ICERs between CHF 10,337 and CHF 91,570 per QALY gained. In subgroup analyses, sofosbuvir dominated telaprevir- and boceprevir-containing treatment in treatment-naïve genotype 1 cirrhotic patients. ICERs of sofosbuvir were above CHF 100,000 per QALY in treatment-naïve, interferon eligible, non-cirrhotic patients infected with genotypes 2 or 3. In deterministic and probabilistic sensitivity analyses, results were generally robust. From a Swiss health care system perspective, treatment of mixed cohorts of cirrhotic and non-cirrhotic patients with CHC genotypes 1-4 with sofosbuvir-containing treatment versus standard treatment would be cost-effective if a threshold of CHF 100,000 per QALY was assumed.

  15. Cost-effectiveness analysis of sofosbuvir compared to current standard treatment in Swiss patients with chronic hepatitis C.

    Science.gov (United States)

    Pfeil, Alena M; Reich, Oliver; Guerra, Ines M; Cure, Sandrine; Negro, Francesco; Müllhaupt, Beat; Lavanchy, Daniel; Schwenkglenks, Matthias

    2015-01-01

    In clinical trials, sofosbuvir showed high antiviral activity in patients infected with hepatitis C virus (HCV) across all genotypes. We aimed to determine the cost-effectiveness of sofosbuvir-based treatment compared to current standard treatment in mono-infected patients with chronic hepatitis C (CHC) genotypes 1-4 in Switzerland. Cost-effectiveness was modelled from the perspective of the Swiss health care system using a lifetime Markov model. Incremental cost-effectiveness ratios (ICERs) used an endpoint of cost per quality-adjusted life year (QALY) gained. Treatment characteristics, quality of life, and transition probabilities were obtained from published literature. Country-specific model inputs such as patient characteristics, mortality and costs were obtained from Swiss sources. We performed extensive sensitivity analyses. Costs and effects were discounted at 3% (range: 0-5%) per year. Sofosbuvir-containing treatment in mixed cohorts of cirrhotic and non-cirrhotic patients with CHC genotypes 1-4 showed ICERs between CHF 10,337 and CHF 91,570 per QALY gained. In subgroup analyses, sofosbuvir dominated telaprevir- and boceprevir-containing treatment in treatment-naïve genotype 1 cirrhotic patients. ICERs of sofosbuvir were above CHF 100,000 per QALY in treatment-naïve, interferon eligible, non-cirrhotic patients infected with genotypes 2 or 3. In deterministic and probabilistic sensitivity analyses, results were generally robust. From a Swiss health care system perspective, treatment of mixed cohorts of cirrhotic and non-cirrhotic patients with CHC genotypes 1-4 with sofosbuvir-containing treatment versus standard treatment would be cost-effective if a threshold of CHF 100,000 per QALY was assumed.

  16. Standardized surgical techniques for adult living donor liver transplantation using a modified right lobe graft: a video presentation from bench to reperfusion.

    Science.gov (United States)

    Hwang, Shin; Ha, Tae-Yong; Ahn, Chul-Soo; Moon, Deok-Bog; Kim, Ki-Hun; Song, Gi-Won; Jung, Dong-Hwan; Park, Gil-Chun; Lee, Sung-Gyu

    2016-08-01

    After having experienced more than 2,000 cases of adult living donor liver transplantation (LDLT), we established the concepts of right liver graft standardization. Right liver graft standardization intends to provide hemodynamics-based and regeneration-compliant reconstruction of vascular inflow and outflow. Right liver graft standardization consists of the following components: Right hepatic vein reconstruction includes a combination of caudal-side deep incision and patch venoplasty of the graft right hepatic vein to remove the acute angle between the graft right hepatic vein and the inferior vena cava; middle hepatic vein reconstruction includes interposition of a uniform-shaped conduit with large-sized homologous or prosthetic grafts; if the inferior right hepatic vein is present, its reconstruction includes funneling and unification venoplasty for multiple short hepatic veins; if donor portal vein anomaly is present, its reconstruction includes conjoined unification venoplasty for two or more portal vein orifices. This video clip that shows the surgical technique from bench to reperfusion was a case presentation of adult LDLT using a modified right liver graft from the patient's son. Our intention behind proposing the concept of right liver graft standardization is that it can be universally applicable and may guarantee nearly the same outcomes regardless of the surgeon's experience. We believe that this reconstruction model would be primarily applied to a majority of adult LDLT cases.

  17. Standardized surgical techniques for adult living donor liver transplantation using a modified right lobe graft: a video presentation from bench to reperfusion.

    Science.gov (United States)

    Hwang, Shin; Ha, Tae-Yong; Ahn, Chul-Soo; Moon, Deok-Bog; Kim, Ki-Hun; Song, Gi-Won; Jung, Dong-Hwan; Park, Gil-Chun; Lee, Sung-Gyu

    2016-08-01

    After having experienced more than 2,000 cases of adult living donor liver transplantation (LDLT), we established the concepts of right liver graft standardization. Right liver graft standardization intends to provide hemodynamics-based and regeneration-compliant reconstruction of vascular inflow and outflow. Right liver graft standardization consists of the following components: Right hepatic vein reconstruction includes a combination of caudal-side deep incision and patch venoplasty of the graft right hepatic vein to remove the acute angle between the graft right hepatic vein and the inferior vena cava; middle hepatic vein reconstruction includes interposition of a uniform-shaped conduit with large-sized homologous or prosthetic grafts; if the inferior right hepatic vein is present, its reconstruction includes funneling and unification venoplasty for multiple short hepatic veins; if donor portal vein anomaly is present, its reconstruction includes conjoined unification venoplasty for two or more portal vein orifices. This video clip that shows the surgical technique from bench to reperfusion was a case presentation of adult LDLT using a modified right liver graft from the patient's son. Our intention behind proposing the concept of right liver graft standardization is that it can be universally applicable and may guarantee nearly the same outcomes regardless of the surgeon's experience. We believe that this reconstruction model would be primarily applied to a majority of adult LDLT cases. PMID:27621745

  18. Gender Dysphoria in Adults.

    Science.gov (United States)

    Zucker, Kenneth J; Lawrence, Anne A; Kreukels, Baudewijntje P C

    2016-01-01

    Gender dysphoria (GD), a term that denotes persistent discomfort with one's biologic sex or assigned gender, replaced the diagnosis of gender identity disorder in the Diagnostic and Statistical Manual of Mental Disorders in 2013. Subtypes of GD in adults, defined by sexual orientation and age of onset, have been described; these display different developmental trajectories and prognoses. Prevalence studies conclude that fewer than 1 in 10,000 adult natal males and 1 in 30,000 adult natal females experience GD, but such estimates vary widely. GD in adults is associated with an elevated prevalence of comorbid psychopathology, especially mood disorders, anxiety disorders, and suicidality. Causal mechanisms in GD are incompletely understood, but genetic, neurodevelopmental, and psychosocial factors probably all contribute. Treatment of GD in adults, although largely standardized, is likely to evolve in response to the increasing diversity of persons seeking treatment, demands for greater client autonomy, and improved understanding of the benefits and limitations of current treatment modalities. PMID:26788901

  19. Financing Adult Education: How Adequate Are Current Sources in Facilitating Access and Participation in Centres in Murang'a South Sub-County, Murang'a County, Kenya?

    Science.gov (United States)

    Maina, Ndonga James; Orodho, John Aluko

    2016-01-01

    The thrust of this study was to examine the level of adequacy of current sources in facilitating access and participation in adult education centres in Murang'a South Sub-County, Murang'a County, Kenya. The study adopted the descriptive survey design. Combinations of purposive and stratified random sampling techniques were used to select 82…

  20. 75 FR 45128 - Current List of Laboratories Which Meet Minimum Standards To Engage in Urine Drug Testing for...

    Science.gov (United States)

    2010-08-02

    ... Guidelines dated April 13, 2004 (69 FR 19644), the following laboratories meet the minimum standards to... Engaged in Urine Drug Testing for Federal Agencies,'' sets strict standards that laboratories must meet in.... Meade, MD 20755-5235, 301-677-7085 *The Standards Council of Canada (SCC) voted to end its...

  1. 75 FR 39023 - Current List of Laboratories Which Meet Minimum Standards To Engage in Urine Drug Testing for...

    Science.gov (United States)

    2010-07-07

    ... Guidelines dated April 13, 2004 (69 FR 19644), the following laboratories meet the minimum standards to... in Urine Drug Testing for Federal Agencies,'' sets strict standards that laboratories must meet in... 20755-5235, 301-677-7085. * The Standards Council of Canada (SCC) voted to end its...

  2. 75 FR 9229 - Current List of Laboratories Which Meet Minimum Standards To Engage in Urine Drug Testing for...

    Science.gov (United States)

    2010-03-01

    ... Guidelines dated April 13, 2004 (69 FR 19644), the following laboratories meet the minimum standards to... in Urine Drug Testing for Federal Agencies,'' sets strict standards that laboratories must meet in... Standards Council of Canada (SCC) voted to end its Laboratory Accreditation Program for Substance...

  3. 75 FR 5088 - Current List of Laboratories Which Meet Minimum Standards To Engage in Urine Drug Testing for...

    Science.gov (United States)

    2010-02-01

    ... Guidelines dated April 13, 2004 (69 FR 19644), the following laboratories meet the minimum standards to... in Urine Drug Testing for Federal Agencies,'' sets strict standards that laboratories must meet in... Standards Council of Canada (SCC) voted to end its Laboratory Accreditation Program for Substance...

  4. 75 FR 27348 - Current List of Laboratories Which Meet Minimum Standards To Engage in Urine Drug Testing for...

    Science.gov (United States)

    2010-05-14

    ... Guidelines dated April 13, 2004 (69 FR 19644), the following laboratories meet the minimum standards to... Urine Drug Testing for Federal Agencies,'' sets strict standards that laboratories must meet in order to... 20755-5235, 301-677-7085. *The Standards Council of Canada (SCC) voted to end its...

  5. 75 FR 32950 - Current List of Laboratories Which Meet Minimum Standards To Engage in Urine Drug Testing for...

    Science.gov (United States)

    2010-06-10

    ... Guidelines dated April 13, 2004 (69 FR 19644), the following laboratories meet the minimum standards to... in Urine Drug Testing for Federal Agencies,'' sets strict standards that laboratories must meet in... 20755-5235. 301-677-7085. * The Standards Council of Canada (SCC) voted to end its...

  6. 75 FR 154 - Current List of Laboratories Which Meet Minimum Standards To Engage in Urine Drug Testing for...

    Science.gov (United States)

    2010-01-04

    ... Guidelines dated April 13, 2004 (69 FR 19644), the following laboratories meet the minimum standards to... in Urine Drug Testing for Federal Agencies,'' sets strict standards that laboratories must meet in... Standards Council of Canada (SCC) voted to end its Laboratory Accreditation Program for Substance...

  7. Using Standardized Interpretation of Chest Radiographs to Identify Adults with Bacterial Pneumonia—Guatemala, 2007–2012

    Science.gov (United States)

    Wortham, Jonathan M.; Gray, Jennifer; Verani, Jennifer; Contreras, Carmen Lucia; Bernart, Chris; Moscoso, Fabiola; Moir, Juan Carlos; Reyes Marroquin, Emma Lissette; Castellan, Rigoberto; Arvelo, Wences; Lindblade, Kim; McCracken, John P.

    2015-01-01

    Background Bacterial pneumonia is a leading cause of illness and death worldwide, but quantifying its burden is difficult due to insensitive diagnostics. Although World Health Organization (WHO) protocol standardizes pediatric chest radiograph (CXR) interpretation for epidemiologic studies of bacterial pneumonia, its validity in adults is unknown. Methods Patients (age ≥15 years) admitted with respiratory infections to two Guatemalan hospitals between November 2007 and March 2012 had urine and nasopharyngeal/oropharyngeal (NP/OP) swabs collected; blood cultures and CXR were also performed at physician clinical discretion. ‘Any bacterial infection’ was defined as a positive urine pneumococcal antigen test, isolation of a bacterial pneumonia pathogen from blood culture, or detection of an atypical bacterial pathogen by polymerase chain reaction (PCR) of nasopharyngeal/oropharyngeal (NP/OP) specimens. ‘Viral infection’ was defined as detection of viral pathogens by PCR of NP/OP specimens. CXRs were interpreted according to the WHO protocol as having ‘endpoint consolidation’, ‘other infiltrate’, or ‘normal’ findings. We examined associations between bacterial and viral infections and endpoint consolidation. Findings Urine antigen and/or blood culture results were available for 721 patients with CXR interpretations; of these, 385 (53%) had endpoint consolidation and 253 (35%) had other infiltrate. Any bacterial infection was detected in 119 (17%) patients, including 106 (89%) pneumococcal infections. Any bacterial infection (Diagnostic Odds Ratio [DOR] = 2.9; 95% confidence Interval (CI): 1.3–7.9) and pneumococcal infection (DOR = 3.4; 95% CI: 1.5–10.0) were associated with ‘endpoint consolidation’, but not ‘other infiltrate’ (DOR = 1.7; 95% CI: 0.7–4.9, and 1.7; 95% CI: 0.7–4.9 respectively). Viral infection was not significantly associated with ‘endpoint consolidation’, ‘other infiltrate,’ or ‘normal’ findings

  8. Intrinsic properties of lumbar motor neurones in the adult G127insTGGG superoxide dismutase-1 mutant mouse in vivo: evidence for increased persistent inward currents

    DEFF Research Database (Denmark)

    Meehan, Claire Francesca; Moldovan, Mihai; Marklund, Stefan L.;

    2010-01-01

    of lumbar motoneurones in the adult presymptomatic G127X mutant are not significantly different from those of wild type. However, at more depolarized membrane potentials, motoneurones in the G127X SOD1 mutants can sustain higher frequency firing, showing less spike frequency adaption and with persistent...... inward currents (PICs) being activated at lower firing frequencies and being more pronounced. Conclusion: We demonstrated that, in vivo, at resting membrane potential, spinal motoneurones of the adult G127X mice do not show an increased excitability. However, when depolarized they show evidence...

  9. Appraising fertilisers: origins of current regulations and standards for contaminants in fertilisers : background of quality standards in the Netherlands, Denmark, Germany, United Kingdom and Flanders

    NARCIS (Netherlands)

    Ehlert, P.A.I.; Posthuma, L.; Römkens, P.F.A.M.; Rietra, R.P.J.J.; Wintersen, A.M.; Wijnen, van H.; Dijk, van T.A.; Schöll, van L.; Groenenberg, J.E.

    2013-01-01

    The standards for contaminants in fertilisers in Denmark, Germany, Flanders, the Netherlands and United Kingdom, are given in the context of the proposals for new European fertiliser legislation. This EU legislation might result in generic limit values for contaminants and input lists of materials,

  10. Validation of five minimally obstructive methods to estimate physical activity energy expenditure in young adults in semi-standardized settings

    DEFF Research Database (Denmark)

    Schneller, Mikkel Bo; Pedersen, Mogens Theisen; Gupta, Nidhi;

    2015-01-01

    participants performed a standardized and semi-standardized protocol including seven daily life activity types, while having their EE measured by indirect calorimetry. Simultaneously, physical activity was quantified by an ActivPAL3, two ActiGraph GT3X+'s and an Actiheart. EE was estimated by the standard...

  11. 75 FR 75485 - Current List of Laboratories Which Meet Minimum Standards To Engage in Urine Drug Testing for...

    Science.gov (United States)

    2010-12-03

    ...'', as amended in the revisions listed above, requires {or set{time} strict standards that Laboratories... Guidelines dated November 25, 2008 (73 FR 71858), the following Laboratories and Instrumented Initial Testing... 20755-5235. 301-677-7085. * The Standards Council of Canada (SCC) voted to end its...

  12. 75 FR 16813 - Current List of Laboratories Which Meet Minimum Standards To Engage in Urine Drug Testing for...

    Science.gov (United States)

    2010-04-02

    ... Guidelines dated April 13, 2004 (69 FR 19644), the following laboratories meet the minimum standards to... Engaged in Urine Drug Testing for Federal Agencies,'' sets strict standards that laboratories must meet in... April 13, 2004 (69 FR 19644). After receiving DOT certification, the laboratory will be included in...

  13. 75 FR 55795 - Current List of Laboratories Which Meet Minimum Standards To Engage in Urine Drug Testing for...

    Science.gov (United States)

    2010-09-14

    ... Guidelines dated April 13, 2004 (69 FR 19644), the following laboratories meet the minimum standards to... in Urine Drug Testing for Federal Agencies,'' sets strict standards that laboratories must meet in... April 13, 2004 (69 FR 19644). After receiving DOT certification, the laboratory will be included in...

  14. Routine immunization of adults in Canada: Review of the epidemiology of vaccine-preventable diseases and current recommendations for primary prevention.

    Science.gov (United States)

    Parkins, Michael D; McNeil, Shelly A; Laupland, Kevin B

    2009-01-01

    Vaccination is one of the greatest achievements in public health of the 20th century. However, the success of vaccine uptake and adherence to immunization guidelines seen in pediatric populations has not been observed among adult Canadians. As a result of the disparity in susceptibility to vaccine-preventable disease, there has been an increasing shift of vaccine-preventable childhood diseases into adult populations. Accordingly, morbidity and mortality due to vaccine-preventable illnesses now occur disproportionately in adults. All Canadians, irrespective of age, should have immunity to measles, mumps, rubella, tetanus, diphtheria, pertussis and varicella. All adult Canadians with significant medical comorbidities or those older than 65 years of age should receive the pneumococcal polysaccharide vaccine and yearly trivalent inactivate influenza vaccines. The present review summarizes the burden of illness of these vaccine-preventable diseases in the Canadian adult population and reviews the current immunization recommendations. Vaccination of all Canadians to these common agents remains a vital tool to decrease individual morbidity and mortality and reduce the overall burden of preventable disease in Canada.

  15. Routine Immunization of Adults in Canada: Review of the Epidemiology of Vaccine-Preventable Diseases and Current Recommendations for Primary Prevention

    Directory of Open Access Journals (Sweden)

    Michael D Parkins

    2009-01-01

    Full Text Available Vaccination is one of the greatest achievements in public health of the 20th century. However, the success of vaccine uptake and adherence to immunization guidelines seen in pediatric populations has not been observed among adult Canadians. As a result of the disparity in susceptibility to vaccine-preventable disease, there has been an increasing shift of vaccine-preventable childhood diseases into adult populations. Accordingly, morbidity and mortality due to vaccine-preventable illnesses now occur disproportionately in adults. All Canadians, irrespective of age, should have immunity to measles, mumps, rubella, tetanus, diphtheria, pertussis and varicella. All adult Canadians with significant medical comorbidities or those older than 65 years of age should receive the pneumococcal polysaccharide vaccine and yearly trivalent inactivate influenza vaccines. The present review summarizes the burden of illness of these vaccine-preventable diseases in the Canadian adult population and reviews the current immunization recommendations. Vaccination of all Canadians to these common agents remains a vital tool to decrease individual morbidity and mortality and reduce the overall burden of preventable disease in Canada.

  16. 物流标准化发展现状研究综述%The Research Review of the Current Situation of the Development of Logistics Standardization

    Institute of Scientific and Technical Information of China (English)

    柳飞; 武赟; 戴铭卿

    2015-01-01

    The thesis reviews current situation of the development of logistics standardization systematically. It summarizes the general research contents from the four aspects: logistics standardization and management system, establishment of the standardization of logistics, implementation of the standardization of logistics and performance evaluation of the standardization.Moreover, the authors put forward with their own view.%本文系统回顾了有关物流标准化发展现状.分别从物流标准化和管理体制、物流标准化的建立、物流标准化的贯彻实施以及物流标准化的绩效评价四个方面进行综述,提出本文观点.

  17. Radiotherapy of high-grade gliomas: current standards and new concepts, innovations in imaging and radiotherapy, and new therapeutic approaches.

    Science.gov (United States)

    Dhermain, Frederic

    2014-01-01

    The current standards in radiotherapy of high-grade gliomas (HGG) are based on anatomic imaging techniques, usually computed tomography (CT) scanning and magnetic resonance imaging (MRI). The guidelines vary depending on whether the HGG is a histological grade 3 anaplastic glioma (AG) or a grade 4 glioblastoma multiforme (GBM). For AG, T2-weighted MRI sequences plus the region of contrast enhancement in T1 are considered for the delineation of the gross tumor volume (GTV), and an isotropic expansion of 15 to 20 mm is recommended for the clinical target volume (CTV). For GBM, the Radiation Therapy Oncology Group favors a two-step technique, with an initial phase (CTV1) including any T2 hyperintensity area (edema) plus a 20 mm margin treated with up to 46 Gy in 23 fractions, followed by a reduction in CTV2 to the contrast enhancement region in T1 with an additional 25 mm margin. The European Organisation of Research and Treatment of Cancer recommends a single-phase technique with a unique GTV, which comprises the T1 contrast enhancement region plus a margin of 20 to 30 mm. A total dose of 60 Gy in 30 fractions is usually delivered for GBM, and a dose of 59.4 Gy in 33 fractions is typically given for AG. As more than 85% of HGGs recur in field, dose-escalation studies have shown that 70 to 75 Gy can be delivered in 6 weeks with relevant toxicities developing in 60 Gy. Trials delivering a SIB into a biological GTV showed the feasibility of this treatment, but the final results, in terms of clinical benefits for HGG patients, are still pending. Many issues have been identified: the variety of MRI and PET machines (and amino-acid tracers), the heterogeneity of the protocols used for image acquisition and post-treatment, the geometric distortion and the unreliable algorithms for co-registration of brain anatomy with functional maps, and the semi-quiescent but highly invasive HGG cells. These issues could be solved by the homogenization of the protocols and software

  18. Influence of Adult Knee Height, Age at First Birth, Migration, and Current Age on Adult Physical Function of Bangladeshi Mothers and Daughters in the United Kingdom and Bangladesh

    Directory of Open Access Journals (Sweden)

    Barry Bogin

    2014-01-01

    Full Text Available In the United Kingdom, Bangladeshi women have the lowest self-reported levels of physical activity and some of the highest levels of metabolic disease of all ethnic groups. To better understand these risks for poor health we employed life course and intergenerational hypotheses to predict lower body physical function in a sample of 121 Bangladeshi mothers (40–70 years old and one of their adult daughters (17–36 years old living in Bangladesh or in the UK. For the mothers, older age and shorter knee height predicted reduced lower body physical function. Knee height is a biomarker of nutrition and health status between birth and puberty. Age at first birth did not have a significant effect. For daughters, older age and migration to the UK predicted reduced lower body physical function. We controlled for total stature and fatness in all analyses. UK-born daughters were taller than BD-born daughters living in the UK, mostly due to differences in knee height. These new findings support previous research indicating that early life health and adequate nutritional status, along with appropriate adult physical activity and diet, may decrease risks for poor physical function, morbidity, and premature mortality.

  19. Compulsive internet use in adults: a study of prevalence and drivers within the current economic climate in the UK

    OpenAIRE

    Quinones-Garcia, Cristina; Korak-Kakabadse, Nada

    2014-01-01

    Compulsive Internet Use (CIU) refers to a maladaptive relationship with the tool, including a loss of control over the use, the use for mood change and withdrawal symptoms. Most studies have relied on student samples, thus little is known about its prevalence in adults. The first objective of this study was to examine CIU in adults that were either employed (N = 260) or unemployed within the last year (N = 256). Second, the drivers of CIU were examined, with a focus on attitudes that reflecte...

  20. Adult-to-adult right lobe living donor liver transplantation: Comparison of endoscopic retrograde cholangiography with standard T2-weighted magnetic resonance cholangiography for evaluation of donor biliary anatomy

    Institute of Scientific and Technical Information of China (English)

    Perdita Wietzke-Braun; Felix Braun; Dieter Müller; Thomas Lorf; Burckhardt Ringe; Giuliano Ramadori

    2006-01-01

    AIM: To compare the value of endoscopic retrograde cholangiography (ERC) and standard T2-weighted magnetic resonance cholangiography (MRC) in the evaluation process as adult-to-adult right lobe living donor liver transplantation (LDLTx) demands a successful outcome, and exact knowledge of the biliary tree is implicated to avoid biliary complications,postoperatively.METHODS: After starting the LDLTx program, 18 liver transplant candidates were selected for LDLTx by a stepwise evaluation process. ERC and standard T2-weighted MRC were performed to evaluate the biliary system of the donor liver. The anatomical findings of ERC and MRC mapping were compared usingthe Ohkubo classification.RESULTS: ERC allowed mapping of the whole biliary system in 15/15 (100%) cases, including 14/15 (93.3%)with biliary variants while routine MRC was only accurate in 2/13 (15.4%) cases. MRC was limited in depicting the biliary system proximal of the hepatic bifurcation.Postoperative biliary complications occurred in 2 donors and 8 recipients. Biliary complications were associated with Ohkubo type C, E or G in 6/8 recipients, and 2/3recipients with biliary leak received a graft with multiple (≥2) bile ducts.CONCLUSION: Pretransplant ERC is safe and superior over standard MRC for detection of biliary variations that occur with a high frequency. However, precise knowledge of biliary variants did not reduce the incidence of postoperative biliary complications.

  1. The application of strength and power related field tests in older adults : criteria, current status and a future perspective

    NARCIS (Netherlands)

    Regterschot, G. Ruben H.; Morat, Tobias; Folkersma, Marjanne; Zijlstra, Wiebren

    2015-01-01

    Leg muscle strength (LMS) and leg muscle power (LMP) are determinants of aspects of functional status and important parameters for measuring intervention effects in older adults. Field tests are often used for the evaluation of LMS and LMP in older persons. However, criteria important for the applic

  2. Comparison of immunogenicity and safety of four doses and four double doses vs. standard doses of hepatitis B vaccination in HIV-infected adults: a randomized, controlled trial.

    Directory of Open Access Journals (Sweden)

    Kanokporn Chaiklang

    Full Text Available BACKGROUND: HBV vaccination is recommended in HIV-infected adults with CD4+ cell count >200/mm(3 although the efficacy is only 33.3% -65%. We conducted a randomized, controlled trial to evaluate the efficacy and safety of three regimens of HBV vaccination at Chiang Mai University Hospital, Thailand. METHODS: From February 4, 2011 to May 4, 2012, 132 HIV-infected adults with CD4+ cell counts >200 cells/mm(3, undetectable plasma HIV-1 RNA, and negative for all HBV markers were randomly assigned to receive one of three recombinant vaccine (Hepavax-Gene(® Berna, Korea regimens: 20 μg IM at months 0, 1, and 6 (Standard doses group, n=44, 20 μg IM at months 0, 1, 2, 6 (four doses group, n=44, or 40 μg IM at months 0, 1, 2, and 6 (four double doses group, n=44. The primary outcomes were to compare the immunogenicity and safety between the four-doses groups with the Standard doses group. RESULTS: At months 7 and 12, the percentages of responders (anti-HBs ≥ 10 mIU/mL were 88.6% and 70.4% in the Standard doses group, 93.2% and 86.4% in the four doses group, (P=0.713 and 0.119, and 95.4% and 88.6% in the four double doses group, (P=0.434 and 0.062, respectively. Factors associated with a high titer level (anti-HBs ≥ 100 mIU/mL were vaccination schedule and younger age. The most common adverse event was pain at the injection site (42.4%; this was significantly more frequent in the four double doses group compared to the Standard doses group. No serious adverse events were observed. CONCLUSIONS: In Northern Thailand, the standard three-doses HBV vaccination in HIV-infected adults with CD4+ cell counts >200 cells/mm(3 and undetectable plasma HIV-1 RNA is highly effective. Although regimens of four injections of either standard or double doses could not significantly increase the response rate, these regimens may induce higher levels of antibody to the virus. TRIAL REGISTRATION INFORMATION: ClinicalTrials.gov; NCT1289106; http://clinicaltrials.gov/ct2

  3. Projection of bootstrap current in the ITER with standard type I ELMy H-mode and steady state scenarios

    Directory of Open Access Journals (Sweden)

    Thawatchai Onjun

    2012-02-01

    Full Text Available The investigation of bootstrap current formation in ITER is carried out using BALDUR integrated predictive modelingcode. The combination of Mixed B/gB anomalous transport model and NLCASS module together with the pedestal model isused in BALDUR code to simulate the time evolution of temperature, density, and plasma current profiles. It was found inthe simulations that without the presence of ITB, a minimal fraction of bootstrap current (as well as low fusion performancewas achieved. The enhancement due to ITB depends sensitively on the strength of toroidal velocity. A sensitivity study wasalso carried out to optimize the bootstrap current fraction and plasma performance. It was found that the bootstrap currentfraction slightly improved; while the plasma performance greatly improved with increasing of NBI power or pedestal temperature.On the other hand, higher impurity concentration resulted in a significant degradation of fusion performance, buta smaller degradation in bootstrap current.

  4. Statistical Association: Alignment of Current U.S. High School Textbooks with the Common Core State Standards for Mathematics

    Science.gov (United States)

    Tran, Dung

    2016-01-01

    This study examined the alignment of three selected U.S. high school textbooks series with the Common Core State Standards for Mathematics (CCSSM) regarding the treatment of statistical association. A framework grounded in the literature for inclusion and exclusion of reasoning about association topics was developed, and textbook entries were…

  5. Dietary Intakes and Eating Habits of College Athletes: Are Female College Athletes Following the Current Sports Nutrition Standards?

    Science.gov (United States)

    Shriver, Lenka H.; Betts, Nancy M.; Wollenberg, Gena

    2013-01-01

    Objective: The objective of this study was to assess dietary intakes and eating habits of female college athletes and compared them with the minimum sports nutrition standards. Participants: Data were obtained from 52 female college athletes from a National Collegiate Athletic Association (NCAA) Division I university between January 2009 and May…

  6. 75 FR 62842 - Current List of Laboratories Which Meet Minimum Standards To Engage in Urine Drug Testing for...

    Science.gov (United States)

    2010-10-13

    ...,'' as amended in the revisions listed above, requires strict standards that Laboratories and... with the Mandatory Guidelines dated April 30, 2010 (75 FR 22809), the following Laboratories and... April 30, 2010 (75 FR 22809). After receiving DOT certification, the laboratory will be included in...

  7. Distance Education Policy Standards: A Review of Current Regional and National Accrediting Organizations in the United States

    Science.gov (United States)

    Keil, Suzanne; Brown, Abbie

    2014-01-01

    A review of distance education accreditation policies and standards written by the six United States regional accrediting commissions and two national accrediting organizations: the Middle States Commission on Higher Education; the New England Association of Schools and Colleges - Commission on Institutions of Higher Education; the North Central…

  8. Current Class Management in Adult Colleges%新形势下成人高校班主任班级管理工作探讨

    Institute of Scientific and Technical Information of China (English)

    马福生

    2011-01-01

    The current status of students in adult colleges is low attendance, poor learning outcomes. Therefore, the management of adult classes in colleges and universities also needs to be improved for a feasible management approach to guarantee a successful teaching.%目前有部分成人高校的学员现状是出勤率较低,学习效果较差,因此对成人高校的班级管理工作还需要不断探索,寻求科学的管理办法,使成人高校的班级管理工作顺利进行,以保证教育教学质量,使学员的学业能顺利完成。

  9. Current Understanding of the Pathways Involved in Adult Stem and Progenitor Cell Migration for Tissue Homeostasis and Repair.

    Science.gov (United States)

    Goichberg, Polina

    2016-08-01

    With the advancements in the field of adult stem and progenitor cells grows the recognition that the motility of primitive cells is a pivotal aspect of their functionality. There is accumulating evidence that the recruitment of tissue-resident and circulating cells is critical for organ homeostasis and effective injury responses, whereas the pathobiology of degenerative diseases, neoplasm and aging, might be rooted in the altered ability of immature cells to migrate. Furthermore, understanding the biological machinery determining the translocation patterns of tissue progenitors is of great relevance for the emerging methodologies for cell-based therapies and regenerative medicine. The present article provides an overview of studies addressing the physiological significance and diverse modes of stem and progenitor cell trafficking in adult mammalian organs, discusses the major microenvironmental cues regulating cell migration, and describes the implementation of live imaging approaches for the exploration of stem cell movement in tissues and the factors dictating the motility of endogenous and transplanted cells with regenerative potential. PMID:27209167

  10. Are the current attempts at standardization of antiphospholipid antibodies still useful? Emerging technologies signal a shift in direction.

    Science.gov (United States)

    Andreoli, Laura; Rizzini, Silvia; Allegri, Flavio; Meroni, Pierluigi; Tincani, Angela

    2008-06-01

    The pathogenic role of antiphospholipid antibodies (aPL) has been widely established over past years in several experimental models and clinical studies. Accordingly, the detection of aPL by immunoassays (anticardiolipin antibodies; anti-beta2 glycoprotein I antibodies) has become a routine practice in the clinical workup of patients with systemic autoimmune diseases. aPL are mostly assayed using commercial ELISA kits, whose performance has not been found to be sufficiently concordant among the different manufacturers. In the past years, collaborative groups have spent considerable effort to reach some form of standardization but this process is still ongoing. Such lack of standardization has recently become even more crucial, as manufacturers have had to face an increasing demand for fully automated tests for aPL, like those test systems that have been developed for other autoantibodies (e.g., antinuclear antibodies, anti-ENA antibodies). We therefore report our recent experience with two newly developed automated methods for anticardiolipin antibodies testing. In particular, we discuss the results obtained using routine samples, as we believe that these better reflect the "real-life" situation in which those automated methods will operate. We also mention other emerging technologies in the field of aPL detection.

  11. ['Gold standard', not 'golden standard'

    NARCIS (Netherlands)

    Claassen, J.A.H.R.

    2005-01-01

    In medical literature, both 'gold standard' and 'golden standard' are employed to describe a reference test used for comparison with a novel method. The term 'gold standard' in its current sense in medical research was coined by Rudd in 1979, in reference to the monetary gold standard. In the same w

  12. Instrumentation Amplifier using Differential voltage second generation current conveyor (DVCCII) in standard 0.18 μm CMOS technology

    OpenAIRE

    Ashish Panchal; Pramod Kumar Jain; D.S. Ajnar

    2011-01-01

    In this paper a new CMOS high performance, high frequency current mode signal DVCC-II is presented. Output stage AB amplifier provides high driving capability ±0.9mA. It provides rail to rail inputoutputoperation. The proposed DVCC-II has been designed in 0.18μm CMOS technology with 1.8V supply voltage. SPECTRA RF simulator is used for circuit simulation. In low voltage sub-micrometer analog circuitaccuracy and precision can be limited by the finite gain as well as by input offset voltage. Pr...

  13. National Institute of Standards and Technology measurement service of the optical properties of biomedical phantoms: current status

    Science.gov (United States)

    Lemaillet, Paul; Cooksey, Catherine C.; Levine, Zachary H.; Pintar, Adam L.; Hwang, Jeeseong; Allen, David W.

    2016-03-01

    The National Institute of Standards and Technology (NIST) has maintained scales for reflectance and transmittance over several decades. The scales are primarily intended for regular transmittance, mirrors, and solid surface scattering diffusers. The rapidly growing area of optical medical imaging needs a scale for volume scattering of diffuse materials that are used to mimic the optical properties of tissue. Such materials are used as phantoms to evaluate and validate instruments under development intended for clinical use. To address this need, a double-integrating sphere based instrument has been installed to measure the optical properties of tissue-mimicking phantoms. The basic system and methods have been described in previous papers. An important attribute in establishing a viable calibration service is the estimation of measurement uncertainties. The use of custom models and comparisons with other established scales enabled uncertainty measurements. Here, we describe the continuation of those efforts to advance the understanding of the uncertainties through two independent measurements: the bidirectional reflectance distribution function and the bidirectional transmittance distribution function of a commercially available solid biomedical phantom. A Monte Carlo-based model is used and the resulting optical properties are compared to the values provided by the phantom manufacturer.

  14. Instrumentation Amplifier using Differential voltage second generation current conveyor (DVCCII in standard 0.18 μm CMOS technology

    Directory of Open Access Journals (Sweden)

    Ashish Panchal

    2011-08-01

    Full Text Available In this paper a new CMOS high performance, high frequency current mode signal DVCC-II is presented. Output stage AB amplifier provides high driving capability ±0.9mA. It provides rail to rail inputoutputoperation. The proposed DVCC-II has been designed in 0.18μm CMOS technology with 1.8V supply voltage. SPECTRA RF simulator is used for circuit simulation. In low voltage sub-micrometer analog circuitaccuracy and precision can be limited by the finite gain as well as by input offset voltage. Proposed circuit features have high CMRR, high gain and bandwidth that can be achieved simultaneously without requiring well matched register.

  15. Imaging in syndrome complex diabetes mellitus. Current standards and future perspectives; Bildgebung im Syndromkomplex Diabetes mellitus. Stellenwert und Chancen

    Energy Technology Data Exchange (ETDEWEB)

    Hetterich, H.; Schafnitzel, A. [Klinikum der Ludwig-Maximilians-Universitaet, Campus Grosshadern, Institut fuer Klinische Radiologie, Muenchen (Germany); Bamberg, F. [Eberhard-Karls-Universitaet, Abteilung fuer Diagnostische und Interventionelle Radiologie, Tuebingen (Germany)

    2015-04-01

    Diabetes mellitus is a highly prevalent multisystemic disorder with numerous potential complications and substantial socioeconomic consequences. In many cases, the patient history, physical examination and laboratory tests are not sufficient for a comprehensive evaluation of complicating disorders. Imaging modalities, such as sonography, computed tomography (CT) and magnetic resonance imaging (MRI) are of major significance in the evaluation of complicating disorders of diabetes according to current guidelines. Examples include assessment of coronary artery disease, peripheral artery disease, stroke and diabetic foot syndrome. Technical developments allow a substantial reduction in radiation dose and scan time in CT and MRI, respectively and could therefore justify a broader application in this patient population. In the future CT and MRI could also be used for the early detection of diabetic complications. Furthermore, they could also be used for risk stratification, e.g. measurement of hepatic fat content and evaluation of atherosclerosis in whole body MRI. Prior to widespread application of advanced imaging techniques in this patient population, improved outcomes with respect to survival, quality of life and cost-effectiveness need to be demonstrated. Diagnostic imaging modalities for the evaluation of the syndrome complex of diabetic disorders should be used according to the current guidelines but the use is predicted to increase given the high potential in this population. (orig.) [German] Diabetes mellitus ist eine hochpraevalente Multisystemerkrankung mit zahlreichen Komplikationen und bedeutenden soziooekonomischen Konsequenzen. Die Folgeerkrankungen koennen oft nicht abschliessend mittels Anamnese, koerperlicher Untersuchung und laborchemischen Verfahren evaluiert werden. Radiologische Verfahren wie die Sonographie, Computertomographie (CT) und Magnetresonanztomographie (MRT) haben gemaess verschiedener Leitlinien einen festen Stellenwert bei der

  16. The Forgotten: Formal Assessment of the Adult Writer

    Science.gov (United States)

    McNair, Daniel J.; Curry, Toi L.

    2013-01-01

    This review of current writing assessment practices focuses upon the adult population, an area significantly underrepresented within psychoeducational literature. As compared to other populations, such as K-12 students, there are few options for the practitioner wishing to evaluate adult writers by means of standardized assessment instruments.…

  17. Current Understanding on the Role of Standard and Immunoproteasomes in Inflammatory/Immunological Pathways of Multiple Sclerosis

    Directory of Open Access Journals (Sweden)

    Elena Bellavista

    2014-01-01

    Full Text Available The ubiquitin-proteasome system is the major intracellular molecular machinery for protein degradation and maintenance of protein homeostasis in most human cells. As ubiquitin-proteasome system plays a critical role in the regulation of the immune system, it might also influence the development and progression of multiple sclerosis (MS. Both ex vivo analyses and animal models suggest that activity and composition of ubiquitin-proteasome system are altered in MS. Proteasome isoforms endowed of immunosubunits may affect the functionality of different cell types such as CD8+ and CD4+ T cells and B cells as well as neurons during MS development. Furthermore, the study of proteasome-related biomarkers, such as proteasome antibodies and circulating proteasomes, may represent a field of interest in MS. Proteasome inhibitors are already used as treatment for cancer and the recent development of inhibitors selective for immunoproteasome subunits may soon represent novel therapeutic approaches to the different forms of MS. In this review we describe the current knowledge on the potential role of proteasomes in MS and discuss the pro et contra of possible therapies for MS targeting proteasome isoforms.

  18. Current Situation and Research of Intelligent Luminaire and Standard%智能灯具及其标准的现状和研究

    Institute of Scientific and Technical Information of China (English)

    施晓红; 庄晓波; 虞再道; 陈超中

    2016-01-01

    Intelligence is the development trend of lighting system and luminaire .From the point of the definition of lighting system and based on the characteristics of intelligent lighting luminaire , this article discussed current situation of intelligent lighting system standards , and presented the basic ideas of developing intelligent standards of luminaire .%智能化是照明系统及其灯具的发展趋势. 本文以照明系统的相关定义为切入点, 在给出智能照明灯具构成特点的基础上, 讨论了智能照明系统标准现状, 表述了开发智能灯具标准的基本思路.

  19. Quantifying Ecological Literacy in an Adult Western Community: The Development and Application of a New Assessment Tool and Community Standard.

    Science.gov (United States)

    Pitman, Sheryn D; Daniels, Christopher B

    2016-01-01

    Knowledge and understanding about how the Earth functions and supports life create the foundation for ecological literacy. Industrialisation, urbanisation and population growth have resulted in changed relationships between many human communities and the natural world. A potential consequence is a compromised capability to make well-informed decisions about how to live sustainably. To gain a measure of ecological literacy within the South Australian community, we collaborated with senior scientists and educators to develop and apply an instrument with the capacity to determine indicative levels of ecological knowledge and understanding. A formal, variable credit, multiple-choice assessment instrument was distributed online to groups and individuals within diverse community sectors and industries. Quantitative analyses of scores indicated that levels of ecological knowledge and understanding within a self-selected sample of over one thousand individuals ranged from very low to extremely high, with the majority of respondents achieving moderate to high scores. This instrument has a demonstrated capacity to determine indicative levels of ecological literacy within and between individuals and groups. It is able to capture mastery of ecological knowledge and understanding achieved through both formal and informal pathways. Using the results, we have been able to establish a range of standards and an aspirational target score for the South Australian community. The value of this work is in its potential to deliver insights into relationships between humans and the rest of the natural world, and into characteristics of eco-literate individuals and communities, that might not otherwise emerge. PMID:26938258

  20. Quantifying Ecological Literacy in an Adult Western Community: The Development and Application of a New Assessment Tool and Community Standard

    Science.gov (United States)

    Pitman, Sheryn D.; Daniels, Christopher B.

    2016-01-01

    Knowledge and understanding about how the Earth functions and supports life create the foundation for ecological literacy. Industrialisation, urbanisation and population growth have resulted in changed relationships between many human communities and the natural world. A potential consequence is a compromised capability to make well-informed decisions about how to live sustainably. To gain a measure of ecological literacy within the South Australian community, we collaborated with senior scientists and educators to develop and apply an instrument with the capacity to determine indicative levels of ecological knowledge and understanding. A formal, variable credit, multiple-choice assessment instrument was distributed online to groups and individuals within diverse community sectors and industries. Quantitative analyses of scores indicated that levels of ecological knowledge and understanding within a self-selected sample of over one thousand individuals ranged from very low to extremely high, with the majority of respondents achieving moderate to high scores. This instrument has a demonstrated capacity to determine indicative levels of ecological literacy within and between individuals and groups. It is able to capture mastery of ecological knowledge and understanding achieved through both formal and informal pathways. Using the results, we have been able to establish a range of standards and an aspirational target score for the South Australian community. The value of this work is in its potential to deliver insights into relationships between humans and the rest of the natural world, and into characteristics of eco-literate individuals and communities, that might not otherwise emerge. PMID:26938258

  1. Magnetic resonance imaging of cystic pancreatic lesions in adults: an update in current diagnostic features and management.

    Science.gov (United States)

    Barral, Matthias; Soyer, Philippe; Dohan, Anthony; Laurent, Valérie; Hoeffel, Christine; Fishman, Elliot K; Boudiaf, Mourad

    2014-02-01

    Magnetic resonance (MR) imaging has become a widespread diagnostic solving tool for the detection and characterization of a large range of pancreatic cystic lesions. Benign and malignant cystic lesions of the pancreas including serous microcystic adenoma, mucinous cystic tumor, intraductal papillary mucinous tumor, solid pseudopapillary tumor, and also the less common lesions such as cystic endocrine tumors, cystic metastases, and lymphangiomas have suggestive MR imaging presentation that allows them to be differentiated from each other. Knowledge of MR imaging findings of cystic pancreatic lesions is critical to help suggest the diagnosis and chose the best therapeutic approach. The purpose of this review is to discuss and illustrate MR imaging features that are helpful for pancreatic cystic lesion detection and characterization and to provide an update in current MR imaging diagnostic features and management. PMID:24263208

  2. Cost-Effectiveness Analysis of Universal Vaccination of Adults Aged 60 Years with 23-Valent Pneumococcal Polysaccharide Vaccine versus Current Practice in Brazil.

    Directory of Open Access Journals (Sweden)

    Patrícia Coelho de Soárez

    Full Text Available To evaluate the cost-effectiveness of introducing universal vaccination of adults aged 60 years with the 23-valent pneumococcal polysaccharide vaccine (PPV23 into the National Immunization Program (NIP in Brazil.Economic evaluation using a Markov model to compare two strategies: (1 universal vaccination of adults aged 60 years with one dose of PPV23 and 2 current practice (vaccination of institutionalized elderly and elderly with underlying diseases. The perspective was from the health system and society. Temporal horizon was 10 years. Discount rate of 5% was applied to costs and benefits. Clinical syndromes of interest were invasive pneumococcal disease (IPD including meningitis, sepsis and others and pneumonia. Vaccine efficacy against IPD was obtained from a meta-analysis of randomized control trials and randomized studies, whereas vaccine effectiveness against pneumonia was obtained from cohort studies. Resource utilization and costs were obtained from the Brazilian Health Information Systems. The primary outcome was cost per life year saved (LYS. Univariate and multivariate sensitivity analysis were performed.The universal vaccination strategy avoided 7,810 hospitalizations and 514 deaths, saving 3,787 years of life and costing a total of USD$31,507,012 and USD$44,548,180, respectively, from the health system and societal perspective. The universal immunization would result in ICERs of USD$1,297 per LYS, from the perspective of the health system, and USD$904 per LYS, from the societal perspective.The results suggest that universal vaccination of adults aged 60 years with the 23-valent pneumococcal polysaccharide vaccine (PPV23 is a very cost-effective intervention for preventing hospitalization and deaths for IPD and pneumonia is this age group in Brazil.

  3. Employment and Adults Who Are Deaf or Hard of Hearing: Current Status and Experiences of Barriers, Accommodations, and Stress in the Workplace.

    Science.gov (United States)

    Punch, Renée

    2016-01-01

    In an integrative review of the literature covering the period 2004-2016, the author presents a current picture of the situation of people who are deaf or hard of hearing (DHH) relative to employment and careers-particularly the barriers, facilitators, and stress levels experienced by working DHH adults. First, an overview is provided of findings from recent reports on employment outcomes for people who are DHH. Second, the author reviews the literature on employment and workplace barriers, facilitators, and accommodations for people who are DHH, and relates findings about DHH people's workplace-related stress and fatigue levels and the associated issues of job demand, job control, and social support in the workplace. The article concludes with a discussion of the implications of these findings, in particular the ways in which barriers to full participation of DHH people in the labor market can be addressed. PMID:27477043

  4. State-specific prevalence of current cigarette smoking and smokeless tobacco use among adults aged ≥18 years - United States, 2011-2013.

    Science.gov (United States)

    Nguyen, Kimberly; Marshall, LaTisha; Hu, Sean; Neff, Linda

    2015-05-22

    Cigarette smoking and the use of smokeless tobacco both cause substantial morbidity and premature mortality. The concurrent use of these products might increase dependence and the risk for tobacco-related disease and death. State-specific estimates of prevalence and relative percent change in current cigarette smoking, smokeless tobacco use, and concurrent cigarette smoking and smokeless tobacco use among U.S. adults during 2011-2013, developed using data from the Behavioral Risk Factor Surveillance System (BRFSS), indicate statistically significant (padvertising and promotion, controlling access to tobacco products, and promoting cessation assistance for smokers to quit, as well as continuing and implementing mass media campaigns that contain graphic anti-smoking ads, such as the Tips from Former Smokers (TIPS) campaign. PMID:25996096

  5. The mediating sex-specific effect of psychological distress on the relationship between adverse childhood experiences and current smoking among adults

    Directory of Open Access Journals (Sweden)

    Strine Tara W

    2012-07-01

    Full Text Available Abstract Background Research suggests that ACEs have a long-term impact on the behavioral, emotional, and cognitive development of children. These disruptions can lead to adoption of unhealthy coping behaviors throughout the lifespan. The present study sought to examine psychological distress as a potential mediator of sex-specific associations between adverse childhood experiences (ACEs and adult smoking. Method Data from 7,210 Kaiser-Permanente members in San Diego California collected between April and October 1997 were used. Results Among women, psychological distress mediated a significant portion of the association between ACEs and smoking (21% for emotional abuse, 16% for physical abuse, 15% for physical neglect, 10% for parental separation or divorce. Among men, the associations between ACEs and smoking were not significant. Conclusions These findings suggest that for women, current smoking cessation strategies may benefit from understanding the potential role of childhood trauma.

  6. The U.S. Forest Service's analysis of cumulative effects to wildlife: A study of legal standards, current practice, and ongoing challenges on a National Forest

    International Nuclear Information System (INIS)

    Cumulative effects analysis (CEA) allows natural resource managers to understand the status of resources in historical context, learn from past management actions, and adapt future activities accordingly. U.S. federal agencies are required to complete CEA as part of environmental impact assessment under the National Environmental Policy Act (NEPA). Past research on CEA as part of NEPA has identified significant deficiencies in CEA practice, suggested methodologies for handling difficult aspects of CEA, and analyzed the rise in litigation over CEA in U.S. courts. This article provides a review of the literature and legal standards related to CEA as it is done under NEPA and then examines current practice on a U.S. National Forest, utilizing qualitative methods in order to provide a detailed understanding of current approaches to CEA. Research objectives were to understand current practice, investigate ongoing challenges, and identify impediments to improvement. Methods included a systematic review of a set of NEPA documents and semi-structured interviews with practitioners, scientists, and members of the public. Findings indicate that the primary challenges associated with CEA include: issues of both geographic and temporal scale of analysis, confusion over the purpose of the requirement, the lack of monitoring data, and problems coordinating and disseminating data. Improved monitoring strategies and programmatic analyses could support improved CEA practice.

  7. 华东电网短路电流计算标准研究%Short-Circuit Current Calculation Standard for East China Power Grid

    Institute of Scientific and Technical Information of China (English)

    冯煜尧; 祝瑞金; 庄侃沁; 李建华

    2012-01-01

    Nowadays five IEC 60909-based calculation methods are commonly used for domestic short-circuit current calculation.On the basis of small system calculation examples,and artificial short circuit field test data for East China Power Grid,this paper theoretically analyzes the validity of the five short-circuit current calculation methods and the calculation influencing factors.Finally,short-circuit current calculation standard is proposed applicable for power grid of no less than 220 kV in East China.%介绍了目前国内短路电流计算工程应用主要根据IEC 60909形成的5种常用的计算方法,从理论分析的角度,结合小系统算例、华东实际电网以及现场人工短路试验实测数据,分析了5种短路计算方法的合理性以及影响短路电流计算的因素,并提出了适合华东220 kV及以上电网短路电流计算的标准。

  8. Inhibitory Effect of Cinobufagin on L-Type Ca2+ Currents, Contractility, and Ca2+ Homeostasis of Isolated Adult Rat Ventricular Myocytes

    Directory of Open Access Journals (Sweden)

    Pinya Li

    2014-01-01

    Full Text Available Cinobufagin (CBG, a major bioactive ingredient of the bufanolide steroid compounds of Chan Su, has been widely used to treat coronary heart disease. At present, the effect of CBG on the L-type Ca2+ current (ICa-L of ventricular myocytes remains undefined. The aim of the present study was to characterize the effect of CBG on intracellular Ca2+ ([Ca2+]i handling and cell contractility in rat ventricular myocytes. CBG was investigated by determining its influence on ICa-L, Ca2+ transient, and contractility in rat ventricular myocytes using the whole-cell patch-clamp technique and video-based edge-detection and dual-excitation fluorescence photomultiplier systems. The dose of CBG (10−8 M decreased the maximal inhibition of CBG by 47.93%. CBG reduced ICa-L in a concentration-dependent manner with an IC50 of 4 × 10−10 M, upshifted the current-voltage curve of ICa-L, and shifted the activation and inactivation curves of ICa-L leftward. Moreover, CBG diminished the amplitude of the cell shortening and Ca2+ transients with a decrease in the time to peak (Tp and the time to 50% of the baseline (Tr. CBG inhibited L-type Ca2+ channels, and reduced [Ca2+]i and contractility in adult rat ventricular myocytes. These findings contribute to the understanding of the cardioprotective efficacy of CBG.

  9. High Seroprotection Rate Induced by Intradermal Administration of a Recombinant Hepatitis B Vaccine in Young Healthy Adults: Comparison with Standard Intramuscular Vaccination

    International Nuclear Information System (INIS)

    Intradermal (ID) vaccination has been proposed as a cost-saving alternative for administration of Hepatitis B (HB) vaccine to implement of mass vaccination of high-risk groups, particularly in developing countries. Therefore, the effectiveness of ID vaccination needs to be evaluated and verified in different ethnic backgrounds. The present study is a randomized trail using a recombinant vaccine (Heberbiovac) to compare immunogenecity and safety of an intradermal low-dose (4 μg) with standard dose (20 μg) of intramuscular (IM) vaccination in healthy Iranian population. Participants were 143 healthy Iranian medical and nursing students randomly allocated to ID or IM vaccination group. The vaccine was inoculated at 0, 1 and 6 months intervals. Serum samples were collected 1 month after the last vaccination and the anti-HBs response was determined using ELISA. The overall seroprotection rate (anti-HBs level ≥ 10IU/L) was 97.3% for ID vaccination group, which was not different from that of IM vaccination group (98.55%)(p= 0.99). Similarly, geometric mean titers (GMT) of anti-HBs were not significantly different between ID (1164.1IU/L) and IM (1071.8IU/L) vaccination groups (p= 0.4). There was no significant difference in seroprotection rate and GMT of anti-HBs between sexes. Although induration and hyperpigmentation at the site of injection were more frequently observed in ID vaccination group, no other clinically adverse effects were observed in both vaccination groups. We conclude that the ID route, which would require one-fifth of the standard dose, would be suitable for use in certain groups such as high-risk adults when the cost of vaccine is the inhibiting factor for mass vaccination

  10. Achieving the salt intake target of 6 g/day in the current food supply in free-living adults using two dietary education strategies.

    Science.gov (United States)

    Ireland, Dani-Maree; Clifton, Peter M; Keogh, Jennifer B

    2010-05-01

    There are national targets for salt intake of 6 g salt/day in Australia and the United States. Despite this, there is limited knowledge about the effectiveness of dietary education in reducing salt intake to this level. The objective of this study was to investigate whether dietary education enabled a reduction in salt consumption. In an 8-week parallel study, 49 healthy free-living adults were recruited from the Adelaide community by newspaper advertisement. In a randomized parallel design, participants received dietary education to choose foods identified by either Australia's National Heart Foundation Tick symbol or by the Food Standards Australia and New Zealand's low-salt guideline of 120 mg sodium/100 g food. Sodium excretion was assessed by 24-hour urinary sodium collections at baseline and weeks 4 and 8. Participants' experiences of following the education strategies were recorded by self-administered questionnaire. These data were collected between August and October 2008. Forty-three participants completed the study. After 8 weeks, urinary sodium excretion decreased from 121+/-50 to 106+/-47 mmol/24 hours (7.3+/-3.0 to 6.4+/-2.8 g salt/24 hours) in the Tick group and from 132+/-44 to 98+/-50 mmol/24 hours (7.9+/-2.6 to 6.0+/-3.0 g salt/24 hours) in the Food Standards Australia New Zealand group (Pfood choice, difficulty when eating out, and increased time associated with identifying foods. In conclusion, dietary sodium reduction is possible among free-living individuals who received dietary advice. PMID:20430138

  11. The long-term effectiveness of need-supportive physical activity counseling compared with a standard referral in sedentary older adults.

    Science.gov (United States)

    Van Hoecke, Ann-Sophie; Delecluse, Christophe; Bogaerts, An; Boen, Filip

    2014-04-01

    This study compared the long-term effectiveness of three physical activity counseling strategies among sedentary older adults: a 1-contact referral (REFER), a 1-contact individualized walking program (WALK), and multiple-contact, individually tailored, and need-supportive coaching based on the self-determination theory (COACH). Participants (n = 442) completed measurements before (pretest), immediately after (posttest), and 1 yr after (follow-up test) a 10-wk intervention. Linear mixed models demonstrated significant time-by-condition interaction effects from pre- to posttest. More specifically, WALK and COACH yielded larger increases in daily steps and self-reported physical activity than REFER. Similarly, self-reported physical activity increased more from pre- to follow-up test in WALK and COACH compared with REFER. Autonomous motivation mediated the effect of perceived need-support on physical activity, irrespective of counseling strategy. These results demonstrate the long-term effectiveness of both a 1-contact individualized walking program and a more time-consuming, need-supportive coaching, especially in comparison with a standard referral to local opportunities.

  12. Prevalence of psychological trauma and association with current health and functioning in a sample of HIV-infected and HIV-uninfected Tanzanian adults.

    Directory of Open Access Journals (Sweden)

    Brian W Pence

    Full Text Available In high income nations, traumatic life experiences such as childhood sexual abuse are much more common in people living with HIV/AIDS (PLWHA than the general population, and trauma is associated with worse current health and functioning. Virtually no data exist on the prevalence or consequences of trauma for PLWHA in low income nations.We recruited four cohorts of Tanzanian patients in established medical care for HIV infection (n = 228, individuals newly testing positive for HIV (n = 267, individuals testing negative for HIV at the same sites (n = 182, and a random sample of community-dwelling adults (n = 249. We assessed lifetime prevalence of traumatic experiences, recent stressful life events, and current mental health and health-related physical functioning. Those with established HIV infection reported a greater number of childhood and lifetime traumatic experiences (2.1 and 3.0 respectively than the community cohort (1.8 and 2.3. Those with established HIV infection reported greater post-traumatic stress disorder (PTSD symptomatology and worse current health-related physical functioning. Each additional lifetime traumatic experience was associated with increased PTSD symptomatology and worse functioning.This study is the first to our knowledge in an HIV population from a low income nation to report the prevalence of a range of potentially traumatic life experiences compared to a matched community sample and to show that trauma history is associated with poorer health-related physical functioning. Our findings underscore the importance of considering psychosocial characteristics when planning to meet the health needs of PLWHA in low income countries.

  13. On the evolution of the standard genetic code: vestiges of critical scale invariance from the RNA world in current prokaryote genomes.

    Directory of Open Access Journals (Sweden)

    Marco V José

    Full Text Available Herein two genetic codes from which the primeval RNA code could have originated the standard genetic code (SGC are derived. One of them, called extended RNA code type I, consists of all codons of the type RNY (purine-any base-pyrimidine plus codons obtained by considering the RNA code but in the second (NYR type and third (YRN type reading frames. The extended RNA code type II, comprises all codons of the type RNY plus codons that arise from transversions of the RNA code in the first (YNY type and third (RNR nucleotide bases. In order to test if putative nucleotide sequences in the RNA World and in both extended RNA codes, share the same scaling and statistical properties to those encountered in current prokaryotes, we used the genomes of four Eubacteria and three Archaeas. For each prokaryote, we obtained their respective genomes obeying the RNA code or the extended RNA codes types I and II. In each case, we estimated the scaling properties of triplet sequences via a renormalization group approach, and we calculated the frequency distributions of distances for each codon. Remarkably, the scaling properties of the distance series of some codons from the RNA code and most codons from both extended RNA codes turned out to be identical or very close to the scaling properties of codons of the SGC. To test for the robustness of these results, we show, via computer simulation experiments, that random mutations of current genomes, at the rates of 10(-10 per site per year during three billions of years, were not enough for destroying the observed patterns. Therefore, we conclude that most current prokaryotes may still contain relics of the primeval RNA World and that both extended RNA codes may well represent two plausible evolutionary paths between the RNA code and the current SGC.

  14. Energy retrofit of an office building by substitution of the generation system: performance evaluation via dynamic simulation versus current technical standards

    International Nuclear Information System (INIS)

    Constructions built in Italy before 1945 (about 30% of the total built stock) feature low energy efficiency. Retrofit actions in this field can lead to valuable energetic and economic savings. In this work, we ran a dynamic simulation of a historical building of the University of Pisa during the heating season. We firstly evaluated the energy requirements of the building and the performance of the existing natural gas boiler, validated with past billings of natural gas. We also verified the energetic savings obtainable by the substitution of the boiler with an air-to-water electrically-driven modulating heat pump, simulated through a cycle-based model, evaluating the main economic metrics. The cycle-based model of the heat pump, validated with manufacturers' data available only at specified temperature and load conditions, can provide more accurate results than the simplified models adopted by current technical standards, thus increasing the effectiveness of energy audits

  15. Lanthanum and zinc sensitivity of GABAA-activated currents in adult medial septum/diagonal band neurons from ethanol dependent rats.

    Science.gov (United States)

    Frye, G D; Fincher, A S; Grover, C A; Jayaprabhu, S

    1996-05-13

    The impact of chronic ethanol treatment, sufficient to induce tolerance and physical dependence, on GABAA receptor function was studied in acutely isolated neurons from the medial septum/nucleus diagonal band (MS/nDB) of adult rats using whole cell, patch-clamp recordings. In ethanol-naive Controls, GABA (0.3-300 microM) induced concentration-dependent increases in Cl- current with a threshold of 0.3-1 microM, a mean maximal current of 7645 +/- 2148 pA at 100-300 microM, an EC50 of 11.3 +/- 1.3 microM and a slope of 1.53 +/- 0.07. GABA-activated currents in neurons from animals receiving two weeks of ethanol liquid diet treatment did not differ significantly on any of these measures. The rate of GABAA receptor desensitization (t1/2 = 6.49 +/- 1.19 s) estimated as the time required for loss of 50% of peak current during sustained application of 10 microM GABA, as well as the residual steady state current remaining following complete desensitization for controls was unchanged by chronic ethanol. The impact of chronic ethanol treatment on the GABAA receptor modulation by lanthanum and zinc which act as positive and negative allosteric modulators, respectively, was also evaluated. Test pulses of 3 microM GABA in control neurons showed maximal potentiation by 141 +/- 30% at approximately 1000 microM lanthanum with an EC50 of 107 +/- 34 microM and a slope of approximately 1. Lanthanum potentiation remained the same following chronic ethanol treatment. Initial estimates based on fitted concentration response curves suggested that maximal inhibition of 3 microM GABA responses by zinc at the level of 70.2 +/- 8.5% in control cells was significantly increased by chronic ethanol treatment to 95.3 +/- 2.5%, although the IC50 of 60.2 +/- 25 microM was not changed. However, this difference was not supported by direct tests of maximal 3-10 mM zinc concentrations. These results suggest that chronic ethanol treatment, sufficient to induce tolerance and physical dependence, probably

  16. The International Labour Standard and Our National Current Situation%国际劳动标准与我国执行现状

    Institute of Scientific and Technical Information of China (English)

    陈盼盼

    2014-01-01

    The article will discuss about the current situation in five core standards for workers from the perspective of origin and development of the international workers ’ convention , including abolishment of slave labor, freedom of gathering , organizing the trade union , collective bargaining right , abolishment of exploiting young workers , and eliminating of occupation discrimination .The article will also talk about the challenges we are facing up to in the process of implementing the international standard for workers as a developing and labor intensive country and discuss on some countermeasures and advice .%本文从国际劳工公约的由来与发展出发,分别从立法层面与执行层面分析我国在五项核心劳工标准中的现状,其中包括废除强迫劳动、结社自由、组织工会和集体谈判权、消除剥削童工、消除就业歧视。通过对现状的分析,指出作为发展中国家、劳动密集型、以贴牌制造生产为主的中国在执行国际劳工标准上所面临的挑战,以及应对挑战的对策建议。

  17. 现行准则下会计人员职业判断能力研究%Study on Accounting Professional Judgment Under Current Standards

    Institute of Scientific and Technical Information of China (English)

    鲁海帆

    2015-01-01

    The existing accounting standards conform to the trend of internationalization, changing from the rule-oriented mode to principle-oriented mode, which no longer carries out provisions for specific operations of the business and only gives accounting principles. This change not only expands the space of judgment of accounting personnel, but also imposes higher requirements of accounting personnel professional knowledge and skills. This paper analyzes the current standards of accounting professional judgment ability, in order to improve the account-ing professional judgment.%现有会计准则顺应了国际化趋势,由原有的规则导向模式转变为原则导向模式,不再对业务的具体操作进行细节性的规定,而仅给出会计核算的原则性要求。这一转变虽然扩大了会计人员的职业判断空间,但也对会计人员的专业知识和技能提出了更高的要求。本文对现有准则下会计人员职业判断能力进行分析,以期对会计职业判断的提高起到一定的推动作用。

  18. Comparison of standardized uptake values measured on {sup 18}F-NaF PET/CT scans using three different tube current intensities

    Energy Technology Data Exchange (ETDEWEB)

    Valadares, Agnes Araujo; Woellner, Eduardo Bechtloff; Sapienza, Marcelo Tatit; Buchpiguel, Carlos Alberto, E-mail: agnesvaladares@me.com [Universidade de Sao Paulo (HC/FMUSP), Sao Paulo, SP (Brazil). Fac. de Medicina. Hospital das Clinicas; Duarte, Paulo Schiavom; Coura-Filho, George Barberio [Instituto do Cancer do Estado de Sao Paulo Octavio Frias de Oliveira (ICESP), Sao Paulo, SP (Brazil)

    2015-01-15

    Objective: to analyze standardized uptake values (SUVs) using three different tube current intensities for attenuation correction on {sup 18}FNaF PET/CT scans. Materials and methods: a total of 254 {sup 18}F-NaF PET/CT studies were analyzed using 10, 20 and 30 mAs. The SUVs were calculated in volumes of interest (VOIs) drawn on three skeletal regions, namely, right proximal humeral diaphysis (RH), right proximal femoral diaphysis (RF), and first lumbar vertebra (LV1) in a total of 712 VOIs. The analyses covered 675 regions classified as normal (236 RH, 232 RF, and 207 LV1). Results: mean SUV for each skeletal region was 3.8, 5.4 and 14.4 for RH, RF, and LV1, respectively. As the studies were grouped according to mAs value, the mean SUV values were 3.8, 3.9 and 3.7 for 10, 20 and 30 mAs, respectively, in the RH region; 5.4, 5.5 and 5.4 for 10, 20 and 30 mAs, respectively, in the RF region; 13.8, 14.9 and 14.5 for 10, 20 and 30 mAs, respectively, in the LV1 region. Conclusion: the three tube current values yielded similar results for SUV calculation. (author)

  19. A wideband current-commutating passive mixer for multi-standard receivers in a 0.18μm CMOS

    Institute of Scientific and Technical Information of China (English)

    Bao Kuan; Fan Xiangning; Li Wei; Wang Zhigong

    2013-01-01

    This paper reports a wideband passive mixer for direct conversion multi-standard receivers.A brief comparison between current-commutating passive mixers and active mixers is presented.The effect of source and load impedance on the linearity of a mixer is analyzed.Specially,the impact of the input impedance of the transimpedance amplifier (TIA),which acts as the load impedance of a mixer,is investigated in detail.The analysis is verified by a passive mixer implemented with 0.18μm CMOS technology.The circuit is inductorless and can operate over a broad frequency range.On wafer measurements show that,with radio frequency (RF) ranges from 700 MHz to 2.3 GHz,the mixer achieves 21 dB of conversion voltage gain with a-1 dB intermediate frequency (IF) bandwidth of 10 MHz.The measured IIP3 is 9 dBm and the measured double-sideband noise figure (NF) is 10.6 dB at 10 MHz output.The chip occupies an area of 0.19 mm2 and drains a current of 5.5 mA from a 1.8 V supply.

  20. Comparison of standardized uptake values measured on 18F-NaF PET/CT scans using three different tube current intensities

    Directory of Open Access Journals (Sweden)

    Agnes Araujo Valadares

    2015-02-01

    Full Text Available Objective: To analyze standardized uptake values (SUVs using three different tube current intensities for attenuation correction on 18FNaF PET/CT scans. Materials and Methods: A total of 254 18F-NaF PET/CT studies were analyzed using 10, 20 and 30 mAs. The SUVs were calculated in volumes of interest (VOIs drawn on three skeletal regions, namely, right proximal humeral diaphysis (RH, right proximal femoral diaphysis (RF, and first lumbar vertebra (LV1 in a total of 712 VOIs. The analyses covered 675 regions classified as normal (236 RH, 232 RF, and 207 LV1. Results: Mean SUV for each skeletal region was 3.8, 5.4 and 14.4 for RH, RF, and LV1, respectively. As the studies were grouped according to mAs value, the mean SUV values were 3.8, 3.9 and 3.7 for 10, 20 and 30 mAs, respectively, in the RH region; 5.4, 5.5 and 5.4 for 10, 20 and 30 mAs, respectively, in the RF region; 13.8, 14.9 and 14.5 for 10, 20 and 30 mAs, respectively, in the LV1 region. Conclusion: The three tube current values yielded similar results for SUV calculation.

  1. The Analysis and Research on Current Situation and Counter measures of Mobile Laboratory Standards in China%中国移动实验室标准的现状分析与对策研究

    Institute of Scientific and Technical Information of China (English)

    陈弘; 苏锡辉; 刘阳

    2014-01-01

    Based on lots of field investigations and researches, this article analyzes in details the current situation of mobile laboratory standards in China, summarizes and explains the existing problems in standardization, and puts forward reasonable measures for the development of the industry.

  2. Effect of hawthorn standardized extract on flow mediated dilation in prehypertensive and mildly hypertensive adults: a randomized, controlled cross-over trial

    Directory of Open Access Journals (Sweden)

    Asher Gary N

    2012-03-01

    Full Text Available Abstract Background Hawthorn extract has been used for cardiovascular diseases for centuries. Recent trials have demonstrated its efficacy for the treatment of heart failure, and the results of several small trials suggest it may lower blood pressure. However, there is little published evidence to guide its dosing. The blood pressure lowering effect of hawthorn has been linked to nitric oxide-mediated vasodilation. The aim of this study was to investigate the relationship between hawthorn extract dose and brachial artery flow mediated dilation (FMD, an indirect measure of nitric oxide release. Methods We used a four-period cross-over design to evaluate brachial artery FMD in response to placebo or hawthorn extract (standardized to 50 mg oligomeric procyanidin per 250 mg extract. Randomly sequenced doses of hawthorn extract (1000 mg, 1500 mg, and 2500 mg and placebo were assigned to each participant. Doses were taken twice daily for 3 1/2 days followed by FMD and a 4-day washout before proceeding to the next dosing period. Results Twenty-one prehypertensive or mildly hypertensive adults completed the study. There was no evidence of a dose-response effect for our main outcome (FMD percent or any of our secondary outcomes (absolute change in brachial artery diameter and blood pressure. Most participants indicated that if given evidence that hawthorn could lower their blood pressure, they would be likely to use it either in conjunction with or instead of lifestyle modification or anti-hypertensive medications. Conclusion We found no evidence of a dose-response effect of hawthorn extract on FMD. If hawthorn has a blood pressure lowering effect, it is likely to be mediated via an NO-independent mechanism. Trial Registration This trial has been registered with ClinicalTrials.gov, a service of the U.S. National Institutes of Health: NCT01331486.

  3. Nuclear aspects of neutral current non-standard ν-nucleus reactions and the role of the exotic μ-→e- transitions experimental limits

    Science.gov (United States)

    Papoulias, D. K.; Kosmas, T. S.

    2014-01-01

    The nuclear aspects of flavour changing neutral current (FCNC) processes, predicted by various new-physics models to occur in the presence of nuclei, are examined by computing the relevant nuclear matrix elements within the context of the quasi-particle RPA using realistic strong two-body forces. One of our aims is to explore the role of the non-standard interactions (NSI) in the leptonic sector and specifically: (i) in lepton flavour violating (LFV) processes involving the neutral particles νℓ and ν, ℓ=e,μ,τ and (ii) in charged lepton flavour violating (cLFV) processes involving the charged leptons ℓ- or ℓ+. As concrete nuclear systems we have chosen the stopping targets of μ-→e- conversion experiments, i.e. the 48Ti nucleus of the PRIME/PRISM experiment at J-PARC and the 27Al of the COMET at J-PARC as well as of the Mu2e at Fermilab. These experiments have been designed to reduce the single event sensitivity down to 10-16-10-18 in searching for charged lepton mixing events. Our goal is, by taking advantage of our detailed nuclear structure calculations and using the present limits or the sensitivity of the aforementioned exotic μ-→e- experiments, to put stringent constraints on the parameters of NSI Lagrangians.

  4. Current sources of lead exposure and their relative contributions to the blood lead levels in the general adult population of Northern France: The IMEPOGE Study, 2008-2010.

    Science.gov (United States)

    Tagne-Fotso, Romuald; Leroyer, Ariane; Howsam, Mike; Dehon, Betty; Richeval, Camille; Nisse, Catherine

    2016-01-01

    There is justification for limiting lead (Pb) exposure as much as possible, given its impact on health at low concentrations. Consequently, the aim of this study was to measure blood lead levels (BLL) and examine exposure factors related to BLL variations in the general adult population of northern France, a current and past industrial area. Two thousand inhabitants of northern France, aged between 20 and 59 years, were recruited using the quota method with caution. Blood lead levels were quantified by inductively coupled plasma-mass spectroscopy (ICP-MS), and variation factors were studied separately in men and women using multivariate stepwise linear and logistic regression models. The geometric mean of the BLL was 18.8 μg/L (95% confidence interval [CI]: 18.3-19.3). Occupational factors affected BLL only in men and represented 14% of total explained variance of BLL. External occupational factors significantly increasing mean levels of BLL were tobacco, consumption of some beverages (wine, coffee, tea, and/or tap water), raw vegetables, housing characteristics (built prior to 1948, Pb piping in the home) and do-it-yourself or leisure activities (paint stripping or rifle shooting). Consumption habits accounted together for 25% and 18% of the total explained variance, respectively, in men and women. Industrial environment did not significantly contribute to BLL variations. Blood lead levels observed in the general population of this industrial part of France did not appear to be excessively elevated compared to values found internationally. Nonetheless, these BLL remain a public health issue in regard to nonthreshold toxicity attributed to Pb. PMID:27074096

  5. Osmotic Edema Rapidly Increases Neuronal Excitability Through Activation of NMDA Receptor-Dependent Slow Inward Currents in Juvenile and Adult Hippocampus.

    Science.gov (United States)

    Lauderdale, Kelli; Murphy, Thomas; Tung, Tina; Davila, David; Binder, Devin K; Fiacco, Todd A

    2015-01-01

    Cellular edema (cell swelling) is a principal component of numerous brain disorders including ischemia, cortical spreading depression, hyponatremia, and epilepsy. Cellular edema increases seizure-like activity in vitro and in vivo, largely through nonsynaptic mechanisms attributable to reduction of the extracellular space. However, the types of excitability changes occurring in individual neurons during the acute phase of cell volume increase remain unclear. Using whole-cell patch clamp techniques, we report that one of the first effects of osmotic edema on excitability of CA1 pyramidal cells is the generation of slow inward currents (SICs), which initiate after approximately 1 min. Frequency of SICs increased as osmolarity decreased in a dose-dependent manner. Imaging of real-time volume changes in astrocytes revealed that neuronal SICs occurred while astrocytes were still in the process of swelling. SICs evoked by cell swelling were mainly nonsynaptic in origin and NMDA receptor-dependent. To better understand the relationship between SICs and changes in neuronal excitability, recordings were performed in increasingly physiological conditions. In the absence of any added pharmacological reagents or imposed voltage clamp, osmotic edema induced excitatory postsynaptic potentials and burst firing over the same timecourse as SICs. Like SICs, action potentials were blocked by NMDAR antagonists. Effects were more pronounced in adult (8-20 weeks old) compared with juvenile (P15-P21) mice. Together, our results indicate that cell swelling triggered by reduced osmolarity rapidly increases neuronal excitability through activation of NMDA receptors. Our findings have important implications for understanding nonsynaptic mechanisms of epilepsy in relation to cell swelling and reduction of the extracellular space. PMID:26489684

  6. The Current Research of Adolescent Internet Use and Library Services for Young Adults of the Foreign Countries%国外青少年网络利用及图书馆青少年服务研究译介

    Institute of Scientific and Technical Information of China (English)

    李婉彬; 谭鑫

    2007-01-01

    美国青少年图书馆服务学会(Young Adult Library Services Association,简写为YALSA)研究委员会于2006年发布了(Current Research Related to Young Adult Services,2000-2005:A Supplement).文章选译了该文献中的部分内容,对国外青少年网络利用及图书馆青少年服务的研究进展作了简要梳理和介绍.

  7. [Anthropometric Indices Used for the Diagnosis of Malnutrition in Adolescents and Adults: Review of the Literature

    OpenAIRE

    Dorlencourt, F.; Priem, V; Legros, D

    2000-01-01

    The International Dietary Energy Consultative Group, sponsored by the World Health Organization (WHO), has done most of the research conducted in the field of adult malnutrition in the late 1980's. These studies were carried out mainly in populations suffering from chronic malnutrition, and led to the current WHO recommendations for the diagnosis and classification of adult malnutrition. Body Mass Index (BMI) is the gold standard to be used in adults, with the following cut-off points identif...

  8. Initial Studies Concerning the Current Status and Problems on the Formulation and Revision of the National Standards for Electric Insulation Materials

    Institute of Scientific and Technical Information of China (English)

    2004-01-01

    @@ Introduction After its accession to the WTO, China must establish an operational mechanism for the standardization work to meet the demands of domestic and foreign markets, and gradually perfect a standard system that meet the needs of national economy and social development.

  9. Training Standardization

    International Nuclear Information System (INIS)

    The article describes the benefits of and required process and recommendations for implementing the standardization of training in the nuclear power industry in the United States and abroad. Current Information and Communication Technologies (ICT) enable training standardization in the nuclear power industry. The delivery of training through the Internet, Intranet and video over IP will facilitate this standardization and bring multiple benefits to the nuclear power industry worldwide. As the amount of available qualified and experienced professionals decreases because of retirements and fewer nuclear engineering institutions, standardized training will help increase the number of available professionals in the industry. Technology will make it possible to use the experience of retired professionals who may be interested in working part-time from a remote location. Well-planned standardized training will prevent a fragmented approach among utilities, and it will save the industry considerable resources in the long run. It will also ensure cost-effective and safe nuclear power plant operation

  10. Radiotherapy of high-grade gliomas:current standards and new concepts, innovations in imaging and radiotherapy, and new therapeutic approaches

    Institute of Scientific and Technical Information of China (English)

    Frederic Dhermain

    2014-01-01

    The current standards in radiotherapy of high-grade gliomas (HGG) are based on anatomic imaging techniques, usually computed tomography (CT) scanning and magnetic resonance imaging (MRI). The guidelines vary depending on whether the HGG is a histological grade 3 anaplastic glioma (AG) or a grade 4 glioblastoma multiforme (GBM). For AG, T2-weighted MRI sequences plus the region of contrast enhancement in T1 are considered for the delineation of the gross tumor volume (GTV), and an isotropic expansion of 15 to 20 mm is recommended for the clinical target volume (CTV). For GBM, the Radiation Therapy Oncology Group favors a two-step technique, with an initial phase (CTV1) including any T2 hyperintensity area (edema) plus a 20 mm margin treated with up to 46 Gy in 23 fractions, followed by a reduction in CTV2 to the contrast enhancement region in T1 with an additional 25 mm margin. The European Organisation of Research and Treatment of Cancer recommends a single-phase technique with a unique GTV, which comprises the T1 contrast enhancement region plus a margin of 20 to 30 mm. A total dose of 60 Gy in 30 fractions is usual y delivered for GBM, and a dose of 59.4 Gy in 33 fractions is typical y given for AG. As more than 85% of HGGs recur in field, dose-escalation studies have shown that 70 to 75 Gy can be delivered in 6 weeks with relevant toxicities developing in60 Gy. Trials delivering a SIB into a biological GTV showed the feasibility of this treatment, but the final results, in terms of clinical benefits for HGG patients, are stil pending. Many issues have been identified: the variety of MRI and PET machines (and amino-acid tracers), the heterogeneity of the protocols used for image acquisition and post-treatment, the geometric distortion and the unreliable algorithms for co-registration of brain anatomy with functional maps, and the semi-quiescent but highly invasive HGG cells. These issues could be solved by the homogenization of the protocols and software

  11. [Standardization of measurement of catalytic activity concentration of enzymes--current situation regarding the external quality assessment program provided by the Japan Medical Association].

    Science.gov (United States)

    Maekawa, Masato

    2010-01-01

    Measurement of the catalytic activity concentration of enzymes has been standardized using a traceability chain, consisting a reference measurement system for enzyme catalytic activity and reference standard-JSCC enzyme. The Japan Medical Association (JMA) has provided an external quality assessment (EQA) survey program for clinical laboratory testing. More than 3,100 clinical laboratories participated in 2008. The EQA program indicated that standardization of the measurement of the catalytic activity concentration of enzymes has been completed for AST, ALT, LD, ALP, gammaGT, and CK in more than 90% laboratories, and for Amy and ChE in nearly 80% of laboratories. Because such a large survey program must use artificial specimens, a matrix effect cannot be avoided, especially in dry chemistry. However, the bias produced by a matrix effect usually has a predictable tendency: it can be corrected. Next, after standardization of the measurement of the catalytic activity concentration of enzymes, we should develop and use common reference intervals. On completing the standardization, we can make standard medical decisions using reference measurement systems and rules.

  12. A system-wide analysis using a senior-friendly hospital framework identifies current practices and opportunities for improvement in the care of hospitalized older adults.

    Science.gov (United States)

    Wong, Ken S; Ryan, David P; Liu, Barbara A

    2014-11-01

    Older adults are vulnerable to hospital-associated complications such as falls, pressure ulcers, functional decline, and delirium, which can contribute to prolonged hospital stay, readmission, and nursing home placement. These vulnerabilities are exacerbated when the hospital's practices, services, and physical environment are not sufficiently mindful of the complex, multidimensional needs of frail individuals. Several frameworks have emerged to help hospitals examine how organization-wide processes can be customized to avoid these complications. This article describes the application of one such framework-the Senior-Friendly Hospital (SFH) framework adopted in Ontario, Canada-which comprises five interrelated domains: organizational support, processes of care, emotional and behavioral environment, ethics in clinical care and research, and physical environment. This framework provided the blueprint for a self-assessment of all 155 adult hospitals across the province of Ontario. The system-wide analysis identified practice gaps and promising practices within each domain of the SFH framework. Taken together, these results informed 12 recommendations to support hospitals at all stages of development in becoming friendly to older adults. Priorities for system-wide action were identified, encouraging hospitals to implement or further develop their processes to better address hospital-acquired delirium and functional decline. These recommendations led to collaborative action across the province, including the development of an online toolkit and the identification of accountability indicators to support hospitals in quality improvement focusing on senior-friendly care.

  13. Instant standard concept for data standards development

    OpenAIRE

    Folmer, Erwin; Kulcsor, Istvan Zsolt; Roes, Jasper

    2013-01-01

    This paper presents the current results of an ongoing research about a new data standards development concept. The concept is called Instant Standard referring to the pressure that is generated by shrinking the length of the standardization process. Based on this concept it is estimated that the development time is reduced by over 50% while maintaining an appropriate quality level for achieving interoperability in practice. The Instant Standard concept for development of data standards is des...

  14. NODC Standard Product: World Ocean Circulation Program (WOCE) Global Data, Version 2: Acoustic doppler current profilers data on CD-ROM (NODC Accession 0000312)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — World-Wide shipboard current data were collected from ADCP casts from the ALPHA HELIX and other platforms as part of World Ocean Circulation Experiment (WOCE). Data...

  15. NODC Standard Format Coastal Ocean Wave and Current (F181) Data from the Atlantic Remote Sensing Land/Ocean Experiment (ARSLOE) (1980) (NODC Accession 0014202)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — This data set contains time series coastal ocean wave and current data collected during the Atlantic Remote Sensing Land/Ocean Experiment (ARSLOE). ARSLOE was...

  16. Adult Cancers in Adolescents and Young Adults.

    Science.gov (United States)

    Laurence, Valérie; Marples, Maria; Stark, Daniel P

    2016-01-01

    The pattern of cancer seen in young people changes with increasing age, transitioning from childhood- to adult-type cancer in adolescence and the third decade. The risk factors, presentation and biology of cancer in young adults differ from those in the older adult population. Factors of particular significance in adolescents and young adults (AYAs) include genetic predisposition to adult-type cancer, diagnostic uncertainty, long-term morbidity and considerations of fertility. New systemic therapies are being introduced that can prolong life and even increase the chance of cure, but the impact on AYAs is uncertain, as these patients are often under-represented in clinical trials. Here, we discuss the management of AYAs with 3 of the most common cancers affecting adults, when they emerge in the AYA populations, and therefore are currently met by medical oncologists - breast cancer, colorectal cancer and melanoma. PMID:27595357

  17. Dietary intake exposure to sulphites in Italy--analytical determination of sulphite-containing foods and their combination into standard meals for adults and children.

    Science.gov (United States)

    Leclercq, C; Molinaro, M G; Piccinelli, R; Baldini, M; Arcella, D; Stacchini, P

    2000-12-01

    The theoretical risk of exceeding the Acceptable Daily Intake (ADI) for sulphites has mostly been examined on the basis of a worst-case scenario. In order to examine the real situation the determination of residue sulphite levels in ready-to-consume foods is required. The aim of this paper is to assess the actual sulphite content of diets obtained from a combination of realistic meals high in sulphite-containing foods. Food products available in Italy containing added sulphites were identified. Overall, 211 samples of foods and beverages (including 85 samples of wine) were collected. The determination of sulphite residues was carried out on the foods which were prepared according to normal domestic practice. It was shown that the diets obtained from these foods would lead to an intake of 23 mg/day in children and 50 mg/day in adults (both slightly above the ADI for respectively a 30 kg child and a 60 kg adult). Among all sulphite-containing foods, the highest contributors to the intake were dried fruit and wine, both ingested without further treatment. The analysis of specific consumption data confirmed the existence of a risk of exceeding the ADI related to sulphite residue levels in wine.

  18. Instant standard concept for data standards development

    NARCIS (Netherlands)

    Folmer, E.; Kulcsar, I.Z.; Roes, J.

    2013-01-01

    This paper presents the current results of an ongoing research about a new data standards development concept. The concept is called Instant Standard referring to the pressure that is generated by shrinking the length of the standardization process. Based on this concept it is estimated that the dev

  19. Expression patterns of nicotinic subunits α2, α7, α8, and β1 affect the kinetics and pharmacology of ACh-induced currents in adult bee olfactory neuropiles.

    Science.gov (United States)

    Dupuis, Julien Pierre; Gauthier, Monique; Raymond-Delpech, Valérie

    2011-10-01

    Acetylcholine (ACh) is the main excitatory neurotransmitter of the insect brain, where nicotinic acetylcholine receptors (nAChRs) mediate fast cholinergic synaptic transmission. In the honeybee Apis mellifera, nAChRs are expressed in diverse structures including the primary olfactory centers of the brain, the antennal lobes (ALs) and the mushroom bodies (MBs), where they participate in olfactory information processing. To understand the nature and properties of the nAChRs involved in these processes, we performed a pharmacological and molecular characterization of nAChRs on cultured Kenyon cells of the MBs, using whole cell patch-clamp recordings combined with single-cell RT-PCR. In all cells, applications of ACh as well as nicotinic agonists such as nicotine and imidacloprid induced inward currents with fast desensitization. These currents were fully blocked by saturating doses of the antagonists α-bungarotoxin (α-BGT), dihydroxy-β-erythroidine (DHE), and methyllycaconitine (MLA) (MLA ≥ α-BGT ≥ DHE). Molecular analysis of ACh-responding cells revealed that of the 11 nicotinic receptor subunits encoded within the honeybee genome, α2, α8, and β1 subunits were expressed in adult Kenyon cells. Comparison with the expression pattern of adult AL cells revealed the supplementary presence of subunit α7, which could be responsible for the kinetic and pharmacological differences observed when comparing ACh-induced currents from AL and Kenyon cells. Together, our data demonstrate the existence of functional nAChRs on adult MB Kenyon cells that differ from nAChRs on AL cells in both their molecular composition and pharmacological properties, suggesting that changing receptor subsets could mediate different processing functions depending on the brain structure within the olfactory pathway. PMID:21734106

  20. The Discrepancies Between the IEC Updated versions for Skin and Hair Care Appliances and the Current National Standards%IEC最新版皮肤及毛发护理器具标准与现行国标之间的差异

    Institute of Scientific and Technical Information of China (English)

    蓝艳莉

    2005-01-01

    The paper introduces the newest IEC standard for the skin & hair care appliance, and then compares them with the standards of the national standard that is carrying at present. The author puts his emphasis on the discrepancies between the IEC updated versions for skin and hair care appliances and the current national standards.

  1. Quality of Survival and Growth in Children and Young Adults in the PNET4 European Controlled Trial of Hyperfractionated Versus Conventional Radiation Therapy for Standard-Risk Medulloblastoma

    Energy Technology Data Exchange (ETDEWEB)

    Kennedy, Colin, E-mail: crk1@soton.ac.uk [University of Southampton Faculty of Medicine and University Hospital Southampton National Health Service Foundation Trust, Southampton (United Kingdom); Bull, Kim [University of Southampton Faculty of Medicine and University Hospital Southampton National Health Service Foundation Trust, Southampton (United Kingdom); Chevignard, Mathilde [Hôpitaux de Saint Maurice, Saint Maurice (France); Neurophysiology, University of Pierre et Marie-Curie Paris 6, Paris (France); Culliford, David [University of Southampton Faculty of Medicine and University Hospital Southampton National Health Service Foundation Trust, Southampton (United Kingdom); Dörr, Helmuth G. [Kinder- und Jugendklinik der Universität Erlangen, Erlangen (Germany); Doz, François [Institut Curie and University Paris Descartes, Sorbonne Paris Cité (France); Kortmann, Rolf-Dieter [Department of Radiation Therapy, University of Leipzig, Leipzig (Germany); Lannering, Birgitta [Department of Pediatrics, The Sahlgren Academy, University of Gothenburg, Gothenburg (Sweden); Massimino, Maura [Fondazione Istituto di Ricovero e Cura a Carattere Scientifico IRCCS Istituto Nazionale dei Tumori, Milan (Italy); Navajas Gutiérrez, Aurora [Hospital Universitario Cruces, Baracaldo-Vizcaya (Spain); Rutkowski, Stefan [University Medical Center Hamburg-Eppendorf, Hamburg (Germany); Spoudeas, Helen A. [Center for Pediatric Endocrinology, University College London, London (United Kingdom); Calaminus, Gabriele [Pediatric Oncology, University of Muenster, Muenster (Germany)

    2014-02-01

    Purpose: To compare quality of survival in “standard-risk” medulloblastoma after hyperfractionated radiation therapy of the central nervous system with that after standard radiation therapy, combined with a chemotherapy regimen common to both treatment arms, in the PNET4 randomised controlled trial. Methods and Materials: Participants in the PNET4 trial and their parents/caregivers in 7 participating anonymized countries completed standardized questionnaires in their own language on executive function, health status, behavior, health-related quality of life, and medical, educational, employment, and social information. Pre- and postoperative neurologic status and serial heights and weights were also recorded. Results: Data were provided by 151 of 244 eligible survivors (62%) at a median age at assessment of 15.2 years and median interval from diagnosis of 5.8 years. Compared with standard radiation therapy, hyperfractionated radiation therapy was associated with lower (ie, better) z-scores for executive function in all participants (mean intergroup difference 0.48 SDs, 95% confidence interval 0.16-0.81, P=.004), but health status, behavioral difficulties, and health-related quality of life z-scores were similar in the 2 treatment arms. Data on hearing impairment were equivocal. Hyperfractionated radiation therapy was also associated with greater decrement in height z-scores (mean intergroup difference 0.43 SDs, 95% confidence interval 0.10-0.76, P=.011). Conclusions: Hyperfractionated radiation therapy was associated with better executive function and worse growth but without accompanying change in health status, behavior, or quality of life.

  2. Quality of Survival and Growth in Children and Young Adults in the PNET4 European Controlled Trial of Hyperfractionated Versus Conventional Radiation Therapy for Standard-Risk Medulloblastoma

    International Nuclear Information System (INIS)

    Purpose: To compare quality of survival in “standard-risk” medulloblastoma after hyperfractionated radiation therapy of the central nervous system with that after standard radiation therapy, combined with a chemotherapy regimen common to both treatment arms, in the PNET4 randomised controlled trial. Methods and Materials: Participants in the PNET4 trial and their parents/caregivers in 7 participating anonymized countries completed standardized questionnaires in their own language on executive function, health status, behavior, health-related quality of life, and medical, educational, employment, and social information. Pre- and postoperative neurologic status and serial heights and weights were also recorded. Results: Data were provided by 151 of 244 eligible survivors (62%) at a median age at assessment of 15.2 years and median interval from diagnosis of 5.8 years. Compared with standard radiation therapy, hyperfractionated radiation therapy was associated with lower (ie, better) z-scores for executive function in all participants (mean intergroup difference 0.48 SDs, 95% confidence interval 0.16-0.81, P=.004), but health status, behavioral difficulties, and health-related quality of life z-scores were similar in the 2 treatment arms. Data on hearing impairment were equivocal. Hyperfractionated radiation therapy was also associated with greater decrement in height z-scores (mean intergroup difference 0.43 SDs, 95% confidence interval 0.10-0.76, P=.011). Conclusions: Hyperfractionated radiation therapy was associated with better executive function and worse growth but without accompanying change in health status, behavior, or quality of life

  3. Guidelines for the Design and Conduct of Clinical Studies in Knee Articular Cartilage Repair: International Cartilage Repair Society Recommendations Based on Current Scientific Evidence and Standards of Clinical Care

    OpenAIRE

    Mithoefer, Kai; Saris, Daniel B.F.; Farr, Jack; Kon, Elizaveta; Zaslav, Kenneth; Cole, Brian J.; Ranstam, Jonas; Yao, Jian; Shive, Matthew; Levine, David; Dalemans, Wilfried; Brittberg, Mats

    2011-01-01

    Objective: To summarize current clinical research practice and develop methodological standards for objective scientific evaluation of knee cartilage repair procedures and products. Design: A comprehensive literature review was performed of high-level original studies providing information relevant for the design of clinical studies on articular cartilage repair in the knee. Analysis of cartilage repair publications and synopses of ongoing trials were used to identify important criteria for t...

  4. RESULTS OF TESTS OF LIGHTNING-RODS WITH UNIVERSAL CLAMPS BY THE APERIODIC IMPULSES OF CURRENT OF ARTIFICIAL LIGHTNING WITH THE PEAK-TEMPORAL PARAMETERS RATIONED ON FOREIGN STANDARDS

    Directory of Open Access Journals (Sweden)

    M.I. Baranov

    2015-06-01

    Full Text Available Purpose. Test in obedience to the requirements of row of operating foreign standards of round metallic lightning-rods with the flat metallic universal clamps of the special type on firmness to direct action of аperiodic impulses of current of temporal form 10/350 μs by amplitude of 50 кА (N− class and 100 кА (H− class. Methodology. The order of leadthrough of these tests is certain the followings normative documents: International IEC 62305-1: 2010, Russian national GOST R IEC 62305-1-2010 and German national DIN EN 50164-1:2008 Standards. Results. Conducted on a powerful high-voltage pulsed current of artificial linear lightning with the peak-temporal parameters and admittances of test rationed on the indicated foreign standards rationed that all of the lightning-rods tested in collection with universal clamps, isolating holders and ceramic elements of roof of technical building were survive electrodynamics and electrothermal action of in-use single short blow of an artificial storm digit. Originality. First in domestic practice the similar model tests of lightning-rods are conducted with universal clamps, executed from different explorer materials, on firmness to flowing to on by it the indicated large impulsive currents of artificial lightning. Practical value. Real firmness to lightning of round copper and zincked steel lightning-rods is certain with the flat copper, zincked steel and non-rusting steel universal clamps of the special execution.

  5. 我国现行会计准则存在的问题及对策研究%The Problems of China's Current Accounting Standards and Countermeasures

    Institute of Scientific and Technical Information of China (English)

    于婧婧

    2014-01-01

    China's accounting standards now have some problems. The defined scopes of the assets need to extend and divide meticulous-ly. The vague provisions of contingent amounts payable need to confirm following the principle of prudence principle of accounting. The use of fair value needs to adopt prudence principle and consider the actual. Facing the problems of identification of non-monetary assets exchange and tax, accounting standards should give an accurate concept and definition, so as to make up for the deficiency.%目前,我国会计准则中资产的界定范围、或有事项处理、公允价值计量与非货币性资产交换等方面存在的问题主要是对资产的定义有待扩展,进行细致划分;或有应付金额确认的规定存在模糊,应该遵照会计的谨慎性原则进行确认;对公允价值的运用既要采用谨慎性原则,还要考虑实际;在处理非货币的资产交换认定和税费的问题时,会计准则应给出一个准确的概念和定义,进而补充各项会计准则的不足之处。

  6. Superallowed 0+→0+ nuclear β decays: A critical survey with tests of the conserved vector current hypothesis and the standard model

    International Nuclear Information System (INIS)

    A complete and critical survey is presented of all half-life, decay-energy, and branching-ratio measurements related to 20 superallowed 0+→0+ decays; no measurements are ignored, although some are rejected for cause and others updated. A new calculation of the statistical rate function f is described and experimental ft values determined. The associated theoretical corrections needed to convert these results into 'corrected' Ft values are discussed, and careful attention is paid to the origin and magnitude of their uncertainties. As an exacting confirmation of the conserved vector current hypothesis, the corrected Ft values are seen to be constant to three parts in 104. These data are also used to set a new limit on any possible scalar interaction (assuming maximum parity violation) of CS/CV=-(0.00005±0.00130). The average Ft value obtained from the survey, when combined with the muon lifetime, yields the up-down quark-mixing element of the Cabibbo-Kobayashi-Maskawa (CKM) matrix, Vud=0.9738±0.0004, and the unitarity test on the top row of the matrix becomes vertical bar Vud vertical bar2+ vertical bar Vus vertical bar2+ vertical bar Vub vertical bar2=0.9966±0.0014 using the Particle Data Group's currently recommended values for Vus and Vub. If Vus comes instead from two recent results on Ke3 decay, the unitarity sum becomes 0.9996(11). Either result can be expressed in terms of the possible existence of right-hand currents. Finally, we discuss the priorities for future theoretical and experimental work with the goal of making the CKM unitarity test more definitive

  7. Using measurements of muscle color, pH, and electrical impedance to augment the current USDA beef quality grading standards and improve the accuracy and precision of sorting carcasses into palatability groups.

    Science.gov (United States)

    Wulf, D M; Page, J K

    2000-10-01

    This research was conducted to determine whether objective measures of muscle color, muscle pH, and(or) electrical impedance are useful in segregating palatable beef from unpalatable beef, and to determine whether the current USDA quality grading standards for beef carcasses could be revised to improve their effectiveness at distinguishing palatable from unpalatable beef. One hundred beef carcasses were selected from packing plants in Texas, Illinois, and Ohio to represent the full range of muscle color observed in the U.S. beef carcass population. Steaks from these 100 carcasses were used to determine shear force on eight cooked beef muscles and taste panel ratings on three cooked beef muscles. It was discovered that the darkest-colored 20 to 25% of the beef carcasses sampled were less palatable and considerably less consistent than the other 75 to 80% sampled. Marbling score, by itself, explained 12% of the variation in beef palatability; hump height, by itself, explained 8% of the variation in beef palatability; measures of muscle color or pH, by themselves, explained 15 to 23% of the variation in beef palatability. When combined together, marbling score, hump height, and some measure of muscle color or pH explained 36 to 46% of the variation in beef palatability. Alternative quality grading systems were proposed to improve the accuracy and precision of sorting carcasses into palatability groups. The two proposed grading systems decreased palatability variation by 29% and 39%, respectively, within the Choice grade and decreased palatability variation by 37% and 12%, respectively, within the Select grade, when compared with current USDA standards. The percentage of unpalatable Choice carcasses was reduced from 14% under the current USDA grading standards to 4% and 1%, respectively, for the two proposed systems. The percentage of unpalatable Select carcasses was reduced from 36% under the current USDA standards to 7% and 29%, respectively, for the proposed systems

  8. The Current Banking Industry Civilized Norms Service Demonstration Unit With the Correct Evaluation Standard%现行银行业文明规范服务示范单位考核标准的评价与矫正

    Institute of Scientific and Technical Information of China (English)

    张翠翠

    2014-01-01

    The current bank of civilized service demonstration unit standards questionable places a lot of. In this paper, ifnd out the shortage of the current service standards through the national banking has to carry out a speciifc analysis and evaluation, put forward the bank civilized service demonstration unit standard correction view, deals with the formulation and evaluation standard of perfection of the principle is:to be practical and realistic attitude, pragmatic style of work, the idea of scientiifc development, characteristic and the demand of the customer for the the banking industry to design and make the evaluation standard, the only way is responsible for the development of China's banking sector.%现行的银行文明服务示范单位标准值得商榷的地方很多。本文通过找出目前全国银行业服务标准存在的不足来进行了具体分析和评价,提出了银行文明服务示范单位标准的矫正观点,阐述了制定和完善评价标准的原则是:要以实事求是的态度,务实的作风,科学发展的思想,针对银行业的特点和客户的实际需求来设计制定考核评价标准,只有这样才是对中国银行业发展负责。

  9. Prevalence of Psychological Trauma and Association with Current Health and Functioning in a Sample of HIV-Infected and HIV-Uninfected Tanzanian Adults.

    OpenAIRE

    Pence, Brian W.; Kristen Shirey; Kathryn Whetten; Bernard Agala; Dafrosa Itemba; Julie Adams; Rachel Whetten; Jia Yao; John Shao

    2012-01-01

    Background In high income nations, traumatic life experiences such as childhood sexual abuse are much more common in people living with HIV/AIDS (PLWHA) than the general population, and trauma is associated with worse current health and functioning. Virtually no data exist on the prevalence or consequences of trauma for PLWHA in low income nations. Methodology/Principal Findings We recruited four cohorts of Tanzanian patients in established medical care for HIV infection (n = 228), individual...

  10. Higher Early Monocyte and Total Lymphocyte Counts Are Associated with Better Overall Survival after Standard Total Body Irradiation, Cyclophosphamide, and Fludarabine Reduced-Intensity Conditioning Double Umbilical Cord Blood Allogeneic Stem Cell Transplantation in Adults.

    Science.gov (United States)

    Le Bourgeois, Amandine; Peterlin, Pierre; Guillaume, Thierry; Delaunay, Jacques; Duquesne, Alix; Le Gouill, Steven; Moreau, Philippe; Mohty, Mohamad; Campion, Loïc; Chevallier, Patrice

    2016-08-01

    This single-center retrospective study aimed to report the impact of early hematopoietic and immune recoveries after a standard total body irradiation, cyclophosphamide, and fludarabine (TCF) reduced-intensity conditioning (RIC) regimen for double umbilical cord blood (dUCB) allogeneic stem cell transplantation (allo-SCT) in adults. We analyzed 47 consecutive patients older than 17 years who engrafted after a dUCB TCF allo-SCT performed between January 2006 and April 2013 in our department. Median times for neutrophil and platelet recoveries were 17 (range, 6 to 59) and 37 days (range, 0 to 164), respectively. The 3-year overall (OS) and disease-free survivals, relapse incidence, and nonrelapse mortality were 65.7%, 57.2%, 27.1%, and 19%, respectively. In multivariate analysis, higher day +30 monocyte (≥615/mm(3); hazard ratio [HR], .04; 95% confidence interval [CI], .004 to .36; P < .01) and day +42 lymphocyte (≥395/mm(3); HR, .16; 95% CI, .03 to .78; P = .02) counts were independently associated with better OS. These results suggest that early higher hematopoietic and immune recovery is predictive of survival after dUCB TCF RIC allo-SCT in adults. Factors other than granulocyte colony-stimulating factor, which was used in all cases, favoring expansion of monocytes or lymphocytes, should be tested in the future as part of the UCB transplantation procedure. PMID:27118570

  11. Diagnostic accuracy of MRI in adults with suspect brachial plexus lesions: A multicentre retrospective study with surgical findings and clinical follow-up as reference standard

    Energy Technology Data Exchange (ETDEWEB)

    Tagliafico, Alberto, E-mail: alberto.tagliafico@unige.it [Institute of Anatomy, Department of Experimental Medicine, University of Genoa, Largo Rosanna Benzi 8, 16132 Genoa (Italy); Succio, Giulia; Serafini, Giovanni [Department of Radiology, Santa Corona Hospital, Pietra Ligure, Italy via XXV Aprile, 38- Pietra Ligure, 17027 Savona (Italy); Martinoli, Carlo [Radiology Department, DISC, Università di Genova, Largo Rosanna Benzi 8, 16138 Genova (Italy)

    2012-10-15

    Objective: To evaluate brachial plexus MRI accuracy with surgical findings and clinical follow-up as reference standard in a large multicentre study. Materials and methods: The research was approved by the Institutional Review Boards, and all patients provided their written informed consent. A multicentre retrospective trial that included three centres was performed between March 2006 and April 2011. A total of 157 patients (men/women: 81/76; age range, 18–84 years) were evaluated: surgical findings and clinical follow-up of at least 12 months were used as the reference standard. MR imaging was performed with different equipment at 1.5 T and 3.0 T. The patient group was divided in five subgroups: mass lesion, traumatic injury, entrapment syndromes, post-treatment evaluation, and other. Sensitivity, specificity with 95% confidence intervals (CIs), positive predictive value (PPV), pre-test-probability (the prevalence), negative predictive value (NPV), pre- and post-test odds (OR), likelihood ratio for positive results (LH+), likelihood ratio for negative results (LH−), accuracy and post-test probability (post-P) were reported on a per-patient basis. Results: The overall sensitivity and specificity with 95% CIs were: 0.810/0.914; (0.697–0.904). Overall PPV, pre-test probability, NPV, LH+, LH−, and accuracy: 0.823, 0.331, 0.905, 9.432, 0.210, 0.878. Conclusions: The overall diagnostic accuracy of brachial plexus MRI calculated on a per-patient base is relatively high. The specificity of brachial plexus MRI in patients suspected of having a space-occupying mass is very high. The sensitivity is also high, but there are false-positive interpretations as well.

  12. 机载软件适航认证标准新进展及展望%Current progress and prospects of airworthiness certification standards in airborne software

    Institute of Scientific and Technical Information of China (English)

    郑军; 黄志球; 徐丙凤

    2012-01-01

    为了满足机载软件适航认证的迫切需求,对机载软件适航认证标准进行分析研究.阐述了DO-178B的发展动因及过程,总结了随着软件开发技术的快速更新DO-178B所表现的不足.说明了对DO-178B进行更新的必要性,并将即将发布的新版本DO-178C与DO-178B进行了对比.根据对比结果重点分析了DO-178C的4个新增特性.对DO-178C所带来的影响以及未来应用进行了展望.%To meet the urgent need of airworthiness certification on airborne software, airworthiness certification standards on airborne software are analyzed. Firstly, the development motivation and process of DO-178B are provided, and the deficiencies of DO-178B in the case of the rapid update of software technology and methods are summarized. Secondly, the necessity of updating DO-178B is pointed out, and a comparison between DO178C which will be published in the near future and DO178B is made. On the foundation of comparison, four new features of DO-178C are analyzed emphatically. Finally, the future prospect of the impaction and application of DO-178C are proposed.

  13. Adult Strabismus

    Science.gov (United States)

    ... Conditions Frequently Asked Questions Español Condiciones Chinese Conditions Adult Strabismus En Español Read in Chinese Can anything be done for adults with strabismus (misaligned eyes)? Yes. Adults can benefit ...

  14. Changes in synaptic and extrasynaptic N-methyl-D-aspartate receptor-mediated currents at early-stage epileptogenesis in adult mice

    Institute of Scientific and Technical Information of China (English)

    Juegang Ju; Sheng-tian Li

    2011-01-01

    Previous reports have shown that N-methyl-D-aspartate (NMDA) receptors are extensively involved in epilepsy genesis and recurrence.Recent studies have shown that synaptic and extrasynaptic NMDA receptors play different, or even opposing, roles in various signaling pathways, including synaptic plasticity and neuronal death.The present study analyzed changes in synaptic and extrasynaptic NMDA receptor-mediated currents during epilepsy onset.Mouse models of lithium chloride pilocarpine-induced epilepsy were established, and hippocampal slices were prepared at 24 hours after the onset of status epilepticus.Synaptic and extrasynaptic NMDA receptor-mediated excitatory post-synaptic currents (NMDA-EPSCs) were recorded in CA1 pyramidal neurons by whole-cell patch clamp technique.Results demonstrated no significant difference in rise and delay time of synaptic NMDA-EPSCs compared with normal neurons.Peak amplitude, area-to-peak ratio,and rising time of extrasynaptic NMDA-EPSCs remained unchanged, but decay of extrasynaptic NMDA-EPSCs was faster than that of normal neurons.These results suggest that extrasynaptic NMDA receptors play a role in epileptogenesis.

  15. EXPERIMENTAL RESEARCHES OF ELECTRO-THERMAL RESISTIBILITY OF SEND-OFFS AND CABLES TO ACTION RATIONED ON THE INTERNATIONAL STANDARD OF IEC 62305-1-2010 OF APERIODIC IMPULSE OF CURRENT OF ARTIFICIAL LIGHTNING

    Directory of Open Access Journals (Sweden)

    M.I. Baranov

    2016-03-01

    Full Text Available Purpose. Experimental researches of electro-thermal resistibility of cable-explorer products, applied in the power electric circuits of objects of electric-power industry, to action on its copper and aluminum parts bearings a current rationed on the International Standard of IEC 62305-1-2010 aperiodic impulse 10/350 μs of current of artificial lightning. Methodology. Electrophysics bases of technique of high tensions and high pulsed currents (HPC, and also scientific and technical bases of planning of devices of high-voltage impulsive technique and measuring HPC in them. Results. Experimental a way the quantitative levels of maximal values maximum of possible and critical closenesses of aperiodic impulse 10/350 μs of current of artificial lightning with rationed on the international standard of IEC 62305-1-2010 peak-temporal parameters and admittances on them in copper (aluminum parts bearings a current of send-offs and cables with a polyethylene (PET and polyvinylchloride (PVCH isolation. Originality. First in world practice on the unique powerful high-voltage generator of HPC of artificial lightning experimental researches of resistibility to lightning of pre-production models of send-offs (cables are conducted with copper (aluminum tendons, PET and PVCH by an isolation, in-use in power electric circuits of electric-power industry objects. Practical value. The use in practice of protecting from lightning of the got results will allow substantially to promote functional and fire-prevention safety of engineering communications of objects of industrial electroenergy in the conditions of action on them of short shots of linear lightning.

  16. The Current Situation of China's Peat industry and the Development of Peat Standardization%浅论我国泥炭产业现状及泥炭标准化发展

    Institute of Scientific and Technical Information of China (English)

    闫木林

    2011-01-01

    本文阐述了国内和国外泥炭产业的发展现状,分析了泥炭产业对发展循环经济,促进可持续发展的重要性和泥炭产业发展的资源、环境问题,以及现今泥炭标准化的发展现状.指出了我国泥炭行业标准化存在的问题,并提出了相应发展方向和对策.%In this paper, domestic and foreign industry development in peat, peat industry analysis for thedevelopment of recycling economy and promote the importance of sustainable development, industrialdevelopment and peat resources, environmental issues, as well as standardization of the current developmentstatus of peat. That the peat industry standardization of China's problems, and the corresponding direction andstrategies.

  17. Comparison of Immunogenicity of Low-Dose Intradermal Hepatitis B Vaccine with the Standard-Dose Intramuscular Vaccination in Young Healthy Iranian Adults

    Directory of Open Access Journals (Sweden)

    Batool Sharifi-Mood

    2008-05-01

    Full Text Available Background and Aims: Although hepatitis B vaccine reliably induces immunity against hepatitis B virus (HBV, the cost of intramuscular (IM vaccination has limited its use, particularly in many developing countries. Intradermal (ID vaccination has been proposed as a cost-saving alternative method for administration of hepatitis B vaccine. However, the effectiveness of ID vaccination needs to be assessed in different ethnic groups. Methods: From September 2006 to March 2008, 185 healthy anti-HBc-negative medical and nursing students at Zahedan University of Medical Sciences who had no history of vaccination against HBV, smoking or hepatitis were evaluated. They were randomly categorized into two groups. In group I (n=91, low-dose (4 |mg recombinant hepatitis B vaccine (Euvax B, Korea was given by intradermal route. In group II (n=94, the standard dose (20 mg of the vaccine was administered intramuscularly at 0, 1, and 6 months. The groups were followed for a minimum of 7 months after the first vaccine dose and tested for anti-HBs titers by ELISA (Diasorin Bio Medica Kit, Saluugia, Italy.Results: Seroprotective anti-HBs titers (titer >10 mIU/mL were achieved in 79 (87% students in group I and in 90 (96% in group II (P=0.031. The difference was much pronounced when the two groups were compared for achieving an anti-HBs titer >300 mIU/mL (P<0.0001.Conclusions: Although ID administration of 4-mg recombinant hepatitis B vaccine is effective, this route is less effective with lower immune response than the IM vaccination.

  18. Transcorneal tube erosion of an Ahmed valve implant in an adult

    Directory of Open Access Journals (Sweden)

    Al-Shahwan Sami

    2010-01-01

    Full Text Available Ahmed valve implants are currently used to manage high-risk complicated adults and pediatric glaucoma when standard filtration surgery is unsuccessful. Despite its success, the Ahmed valve shunt has significant complications particularly in the anterior segment. We report an unusual case of transcorneal tube erosion of an Ahmed valve implant in an adult that resulted from long-standing tube-corneal touch. Periodic observation of tube position is recommended.

  19. Defining Cigarette Smoking Status in Young Adults: A Comparison of Adolescent vs Adult Measures

    Science.gov (United States)

    Delnevo, Cristine D.; Lewis, M. Jane; Kaufman, Ira; Abatemarco, Diane J.

    2004-01-01

    Objective: To determine the agreement between 2 measures (adult vs adolescent) of current cigarette smoking among young adults. Methods: We examined data from 1007 young adults from the New Jersey Adult Tobacco Survey. The adult measure incorporates lifetime and present use, whereas the adolescent measure assesses past 30-day use. The kappa…

  20. Changes in smoking prevalence among U.S. adults by state and region: Estimates from the Tobacco Use Supplement to the Current Population Survey, 1992-2007

    Directory of Open Access Journals (Sweden)

    Center Melissa M

    2011-06-01

    Full Text Available Abstract Background Tobacco control policies at the state level have been a critical impetus for reduction in smoking prevalence. We examine the association between recent changes in smoking prevalence and state-specific tobacco control policies and activities in the entire U.S. Methods We analyzed the 1992-93, 1998-99, and 2006-07 Tobacco Use Supplement to the Current Population Survey (TUS-CPS by state and two indices of state tobacco control policies or activities [initial outcome index (IOI and the strength of tobacco control (SOTC index] measured in 1998-1999. The IOI reflects cigarette excise taxes and indoor air legislation, whereas the SOTC reflects tobacco control program resources and capacity. Pearson Correlation coefficient between the proportionate change in smoking prevalence from 1992-93 to 2006-07 and indices of tobacco control activities or programs was the main outcome measure. Results Smoking prevalence decreased from 1992-93 to 2006-07 in both men and women in all states except Wyoming, where no reduction was observed among men, and only a 6.9% relative reduction among women. The percentage reductions in smoking in men and women respectively were the largest in the West (average decrease of 28.5% and 33.3% and the smallest in the Midwest (18.6% and 20.3%, although there were notable exceptions to this pattern. The decline in smoking prevalence by state was correlated with the state's IOI in both women and men (r = -0.49, p Conclusion State level policies on cigarette excise taxes and indoor air legislation correlate strongly with reductions in smoking prevalence since 1992. Strengthening and systematically implementing these policies could greatly accelerate further reductions in smoking.

  1. DOE technical standards list: Department of Energy standards index

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1999-05-01

    This Department of Energy (DOE) technical standards list (TSL) has been prepared by the Office of Nuclear Safety Policy and Standards (EH-31) on the basis of currently available technical information. Periodic updates of this TSL will be issued as additional information is received on standardization documents being issued, adopted, or canceled by DOE. This document was prepared for use by personnel involved in the selection and use of DOE technical standards and other Government and non-Government standards. This TSL provides listings of current DOE technical standards, non-Government standards that have been adopted by DOE, other standards-related documents in which DOE has a recorded interest, and canceled DOE technical standards. Information on new DOE technical standards projects, technical standards released for coordination, recently published DOE technical standards, and activities of non-Government standards bodies that may be of interest to DOE is published monthly in Standards Actions.

  2. Young Adult Smoking Behavior

    Science.gov (United States)

    Ling, Pamela M.; Neilands, Torsten B.; Glantz, Stanton A.

    2009-01-01

    Background Young adults have the highest smoking rate of any age group in the U.S., and new strategies to decrease young adult smoking are needed. The objective of the current study was to identify psychographic and demographic factors associated with current smoking and quitting behaviors among young adults. Methods Attitudes, social groups, and self-descriptors, including supporting action against the tobacco industry, advertising receptivity, depression, alcohol use, and other factors associated with smoking were tested for associations with smoking behaviors in a 2005 cross-sectional survey of 1528 young adults (aged 18–25 years) from a web-enabled panel. Analyses were conducted in 2007. Results Being older was associated with current smoking, whereas having some higher education and being African American or Hispanic were negatively associated with smoking. Supporting action against the tobacco industry was negatively associated with smoking (AOR=0.34 [95% CI=0.22, 0.52]). Perceived usefulness of smoking, exposure to smokers, increased perceived smoking prevalence, receptivity to tobacco advertising, binge drinking, and exposure to tobacco advertising in bars and clubs were associated with smoking. Supporting action against the tobacco industry was associated with intentions to quit smoking (AOR= 4.43 [95% CI=2.18, 8.60]). Conclusions Young adults are vulnerable to tobacco-industry advertising. Media campaigns that denormalize the tobacco industry and appeal to young adults appear to be a powerful intervention to decrease young adult smoking. PMID:19269128

  3. Estimated use of abacavir among adults and children enrolled in public sector antiretroviral therapy programmes in Gauteng, South Africa

    Directory of Open Access Journals (Sweden)

    D Evans

    2012-09-01

    Full Text Available In South Africa, abacavir (ABC is currently recommended as part of first- and second-line antiretroviral therapy (ART for HIV-positive paediatric patients. Concerns about overprescribing of the drug, particularly to adults, led to an analysis of ABC use in public sector ART programmes. We investigated current prescription of the drug to adults and children accessing ART in 4 public sector programmes across Gauteng Province, South Africa. ABC was almost exclusively prescribed to children initiating ART and adults requiring regimen changes due to drug toxicities. Patterns of ABC use among HIV-positive paediatric patients followed national ART treatment guidelines on the application of the drug. Although ABC is commonly used in the private sector for adults, the current national ART treatment guidelines for adults and adolescents should include ABC as an alternative to standard first- or second-line ART.

  4. Adult Education and Adult Learning

    DEFF Research Database (Denmark)

    Illeris, Knud

    Kort beskrivelse Bogen, 'Adult Education og Adult Learning', giver et fyldestgørende overblik over forståelsen af voksenuddannelse og læring. Abstract I "Adult Education and Adult Learning' ser Knud Illeris på voksenuddannelse fra to perspektiver. På den ene side beskrives de aktuelle udfordringer...

  5. Modern Biotechnology—Current Standards in Japan

    Institute of Scientific and Technical Information of China (English)

    2001-01-01

    @@In the past few years, a new technology, biotechnology, has come into practical use internationally. It is prospective that application of biotechnology in the field of food production may lead to improved food quality and productivity.   Modern biotechnology, through the use of recombinant DNA techniques, has been used for food production for some time now. Therefore, particular attention should be paid to the safety of foods and food additives produced by recombinant DNA techniques. For this reason, Japan set out the “Guideline for Safety Assessment of Foods and Food Additives Produced by Recombinant DNA Techniques” and “Guideline for Manufacturing Foods and Food Additives Produced by Recombinant DNA Techniques,” in 1991.

  6. [Treatment of chronic back pain: current standards].

    Science.gov (United States)

    Märker-Hermann, E; Kiltz, U; Braun, J

    2014-12-01

    Back pain is a significant medical problem and one of the most common causes of medical consultations and missed work. In acute low back pain, patients with "red flags" indicating a serious underlying spinal or extraspinal disease must be identified by medical evaluation. Most cases of acute back pain are non-specific, and education, physical activity and pain medication is recommended. In addition, yellow flags (risks of developing chronic pain) should be recognized. The management of low back pain has been addressed by the German National Disease Management Guideline (NVL) low back pain published in 2010. This guideline evaluates the evidence and effectiveness of diagnostic and therapeutic interventions with a focus on nonspecific back pain. For chronic nonspecific low back pain intervention based on nondrug and drug therapy and a multiprofessional assessment is recommended. In patients with chronic inflammatory low back pain with onset before the age of 45, rheumatic spondyloarthritis should be considered. Recently, a guideline (S3-Leitlinie) for the management of axial spondyloarthritis including ankylosing spondylitis has become available. It provides evidence of physical and drug therapy including nonsteroidal antirheumatic and Tumor necrosis factor (TNF) inhibitor therapy. PMID:25465277

  7. Serological diagnosis of toxoplasmosis and standardization.

    Science.gov (United States)

    Zhang, Kuo; Lin, Guigao; Han, Yanxi; Li, Jinming

    2016-10-01

    Humans can be infected by the intracellular parasite Toxoplasma gondii, which causes toxoplasmosis, a common parasitic disease. Although the infection is generally asymptomatic for most adults, severe complications may occur in some individuals, especially women in early pregnancy. Serologic diagnosis is used as a routine practice to determine the immune status for infection by T. gondii. In this review, we attempt to provide an overview of the serological diagnosis of toxoplasmosis, including diagnostic strategy, current problems in detection with specific antibodies, and the standardization of T. gondii serological detection. PMID:27470936

  8. The Autism Diagnostic Observation Schedule, Module 4: Revised Algorithm and Standardized Severity Scores

    Science.gov (United States)

    Hus, Vanessa; Lord, Catherine

    2014-01-01

    The recently published Autism Diagnostic Observation Schedule, 2nd edition (ADOS-2) includes revised diagnostic algorithms and standardized severity scores for modules used to assess younger children. A revised algorithm and severity scores are not yet available for Module 4, used with verbally fluent adults. The current study revises the Module 4…

  9. Department of Energy Standards Index

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-08-01

    This TSL, intended for use in selecting and using DOE technical standards and other Government and non-Government standards, provides listing of current and inactive DOE technical standards, non-Government standards adopted by DOE, other Government documents in which DOE has a recorded interest, and cancelled DOE technical standards.

  10. DOE technical standards list. Department of Energy standards index

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-08-01

    This document was prepared for use by personnel involved in the selection and use of DOE technical standards and other Government and non-Government standards. This TSL provides listing of current DOE technical standards, non-Government standards that have been adopted by DOE, other Government documents in which DOE has a recorded interest, and canceled DOE technical standards. Information on new DOE technical standards projects, technical standards released for coordination, recently published DOE technical standards, and activities of non-Government standards bodies that may be of interest to DOE is published monthly in Standards Actions.

  11. 成人注意力缺陷/多动障碍的流行病学研究和药物治疗进展%Epidemiology and Pharmacotherapy of Adult Attention Deifcit/Hyperactivity Disorder:Current Status

    Institute of Scientific and Technical Information of China (English)

    刘治军

    2012-01-01

    注意力缺陷/多动障碍(attention deficit/hyperactivity disorder,ADHD)是儿童常见的神经发育异常疾病,大多数儿童期ADHD将持续带入到成人期。2012年由美国精神病学协会颁布的DSM-5首次给出了成人ADHD的诊断,规范了成人ADHD的治疗。目前主要的治疗药物包括哌甲酯、苯丙胺类神经兴奋剂类、托莫西汀、安非他酮和三环类抗抑郁药等非兴奋剂类,其它药物如文拉法辛、瑞波西汀、莫达非尼、奥卡西平、普萘洛尔等也被尝试用于治疗成人ADHD,并取得一定疗效。%Attention deficit/hyperactivity disorder(ADHD)is the most frequently diagnosed neuro-developmental disorder in children and most of the children ADHD cases can persist to adulthood. The DSM-5 developed and published by American Psychiatric Association(APA)at 2012 firstly gives the more appropriate diagnosis criteria and regulates pharmacotherapies for adult ADHD. The currently used medications include neural stimulants(e.g. methylphenidate and amphetamines)and non-stimulants(e.g. atomoxetine,buproprion and tricyclic antidepressants). Other medications such as venlafaxine,reboxetine,modafinil,oxcarbazepine and propranolol are also tried to treat adult ADHD and showed a certain effects.

  12. Engaging the Adult Learner Generational Mix

    Science.gov (United States)

    Holyoke, Laura; Larson, Erick

    2009-01-01

    Educators and Trainers both focus on adult learning theory when teaching. In the workforce, as well as in higher education, current literature pertaining to adult learners tends to lump all adults into the same category. Scant research exists that reviews the adult learner through a generational lens. This paper examines the elements that engage…

  13. Becoming adult educators in Denmark

    DEFF Research Database (Denmark)

    Milana, Marcella; Søgaard Lund, Lise

    2009-01-01

    In this paper we present an analysis of identity-construction processes among adult educators in Denmark and we address the question how adult educators develop professionalism, not least by taking advantage of existing opportunity structures for current and prospective adult educators. A between......-cases analysis of fifteen narrative interviews explores the professional pathways towards adult education, the perceived images of a (professional) adult educator, processes of identification with concrete or imaginary communities, and motivation for adult educator to enrol in current opportunity structures...... to better qualify as professionals. The findings suggest that identity-building among Danish adult educators fluctuates between several processes of identification with either concrete or imaginary communities to which they relate at home, at work etc., but which do not necessarily result from a strong...

  14. Service Providers' Perceptions of Active Ageing among Older Adults with Lifelong Intellectual Disabilities

    Science.gov (United States)

    Buys, L.; Aird, R.; Miller, E.

    2012-01-01

    Background: Considerable attention is currently being directed towards both active ageing and the revising of standards for disability services within Australia and internationally. Yet, to date, no consideration appears to have been given to ways to promote active ageing among older adults with intellectual disabilities (IDs). Methods:…

  15. Older Adults and Food Safety

    Science.gov (United States)

    ... Standard Forms FSIS United States Department of Agriculture Food Safety and Inspection Service About FSIS District Offices Careers ... JSR 286) Actions ${title} Loading... Older Adults and Food Safety An adage states, "With age, comes wisdom." Hopefully ...

  16. Are national quality standards for traditional Chinese herbal medicine sufficient? Current governmental regulations for traditional Chinese herbal medicine in certain Western countries and China as the Eastern origin country.

    Science.gov (United States)

    Dobos, G J; Tan, L; Cohen, M H; McIntyre, M; Bauer, R; Li, X; Bensoussan, A

    2005-09-01

    Traditional Chinese herbal Medicine (TCHM) has been gaining interest and acceptance world wide. TCHM provides on the one side promising perspective of scientific interest and on the other side possible health risks if TCHM drugs are not controlled with respect to quality standards or if practitioners for TCHM are not well trained. This paper outlines an introduction to the scientific aspects and potential risks of TCHM therapy followed by a brief, exploratory overview of the current status of TCHM regulations in certain Western countries like the USA, United Kingdom, Germany, Australia and in China as the Eastern origin country of TCHM. Legal foundations to establish quality and safety standards for TCHM crude drugs and ready-made formulas exist in some countries on a local basis but in practice are poorly enforced, where this products have no drug status. In addition practitioners treating patients with TCHM should be well versed in the pharmacology, side effects, and interactions of these substances with Western medicines and should be certified on a regular basis.

  17. Parameter Estimation of Standard Signals for Transient Characteristics Test of Current Transformer%电流互感器暂态特性试验用标准信号的参数估计

    Institute of Scientific and Technical Information of China (English)

    冯宇; 万罡; 舒开旗; 汪本进; 陈晓明; 吴士普

    2014-01-01

    电流互感器的暂态特性是影响继保装置正确动作、攸关系统安全稳定的关键因素之一,对入网的电流互感器开展暂态特性试验或检测具有重要意义。为准确掌握试验用标准信号的信息,提出了相应的参数估计方法。在噪声允许的范围内,求标准信号的正极大值。结合暂态发生的时间信息,截取出暂态时段内的各个正极大值,再利用对数变换将其转换为直线函数,使用最小二乘法拟合得到直线的截距与斜率,分别对应暂态电流的幅值及时间常数。仿真结果表明:当标准信号的采样频率为6.4 kHz并伴有20 dB高斯白噪声时,所提方法能精确估计出暂态发生时刻,对暂态电流时间常数的估计精度高于暂态电流幅值,暂态电流时间常数的估计范围为80∼210 ms。所得结论为开展电流互感器的暂态特性试验提供了参考依据。%Transient performance of the current transformer (CT) is one of key factors that relates to the security and stability of power grids and whether the protective relaying could be operated correctly, so it is of great significance for grid-connected CT to perform transient performance test or detection. To master the information of standard signals for the test, corresponding parameter estimation method is proposed to solve the positive maximum of standard signals within the allowed noise range. Combining with the time information when the transient process happens, positive maximums within the transient time period are captured, then they are transformed into linear function by logarithmic transformation, and then using least square fitting both intercept and slope of the linear function are obtained, which correspond to the amplitude and time constant of transient current respectively. Simulation results show that when the sampling frequency of the standard signal is 6.4 kHz accompanied with 20 dB of Gaussian white noise, using the

  18. Developmental dyslexia in adults: behavioural manifestations and cognitive correlates.

    Science.gov (United States)

    Nergård-Nilssen, Trude; Hulme, Charles

    2014-08-01

    This paper explores the nature of residual literacy and cognitive deficits in self-reported dyslexic Norwegian adults. The performance of 26 self-reported dyslexic adults was compared with that of a comparison group of 47 adults with no history of reading or spelling difficulties. Participants completed standardized and experimental measures tapping literacy skills, working memory, phonological awareness and rapid naming. Spelling problems were the most prominent marker of dyslexia in adults, followed by text reading fluency and nonword decoding. Working memory and phoneme awareness explained unique variance in spelling, whereas rapid automatized naming explained unique variance in reading fluency and nonword reading. The moderate to strong correlations between self-reported history, self-rating of current literacy skills and outcomes on literacy tests indicate that adults estimated their literacy skills fairly well. Results suggest that spelling impairments, more strongly than reading impairments, make adults perceive themselves as being dyslexic. A combination of three literacy and three cognitive tests predicted group membership with 90.4% accuracy. It appears that weaknesses in phoneme awareness, rapid automatized naming and working memory are strong and persistent correlates of literacy problems even in adults learning a relatively transparent orthography.

  19. Adult flatfoot.

    Science.gov (United States)

    Toullec, E

    2015-02-01

    Adult flatfoot is defined as a flattening of the medial arch of the foot in weight-bearing and lack of a propulsive gait. The 3 lesion levels are the talonavicular, tibiotarsal and midfoot joints. The subtalar joint is damaged by the consequent rotational defects. Clinical examination determines deformity and reducibility, and assesses any posterior tibialis muscle deficit, the posterior tibialis tendon and spring ligament being frequently subject to degenerative lesions. Radiographic examination in 3 incidences in weight-bearing is essential, to determine the principal level of deformity. Tendon (posterior tibialis tendon) and ligamentous lesions (spring ligament and interosseous ligament) are analyzed on MRI or ultrasound. In fixed deformities, CT explores for arthritic evolution or specific etiologies. 3D CT reconstruction can analyze bone and joint morphology and contribute to the planning of any osteotomy. Medical management associates insoles and physiotherapy. Acute painful flatfoot requires strict cast immobilization. Surgical treatment associates numerous combinations of procedures, currently under assessment for supple flatfoot: for the hindfoot: medial slide calcaneal osteotomy, calcaneal lengthening osteotomy, or arthroereisis; for the midfoot: arthrodesis on one or several rays, or first cuneiform or first metatarsal osteotomy; for the ankle: medial collateral ligament repair with tendon transfer. Fixed deformities require arthrodesis of one or several joint-lines in the hindfoot; for the ankle, total replacement after realignment of the foot, or tibiotalocalcaneal fusion or ankle and hindfoot fusion; and, for the midfoot, cuneonavicular or cuneometatarsal fusion. Tendinous procedures are often associated. Specific etiologies may need individualized procedures. In conclusion, adult flatfoot tends to be diagnosed and managed too late, with consequent impact on the ankle, the management of which is complex and poorly codified.

  20. Adult flatfoot.

    Science.gov (United States)

    Toullec, E

    2015-02-01

    Adult flatfoot is defined as a flattening of the medial arch of the foot in weight-bearing and lack of a propulsive gait. The 3 lesion levels are the talonavicular, tibiotarsal and midfoot joints. The subtalar joint is damaged by the consequent rotational defects. Clinical examination determines deformity and reducibility, and assesses any posterior tibialis muscle deficit, the posterior tibialis tendon and spring ligament being frequently subject to degenerative lesions. Radiographic examination in 3 incidences in weight-bearing is essential, to determine the principal level of deformity. Tendon (posterior tibialis tendon) and ligamentous lesions (spring ligament and interosseous ligament) are analyzed on MRI or ultrasound. In fixed deformities, CT explores for arthritic evolution or specific etiologies. 3D CT reconstruction can analyze bone and joint morphology and contribute to the planning of any osteotomy. Medical management associates insoles and physiotherapy. Acute painful flatfoot requires strict cast immobilization. Surgical treatment associates numerous combinations of procedures, currently under assessment for supple flatfoot: for the hindfoot: medial slide calcaneal osteotomy, calcaneal lengthening osteotomy, or arthroereisis; for the midfoot: arthrodesis on one or several rays, or first cuneiform or first metatarsal osteotomy; for the ankle: medial collateral ligament repair with tendon transfer. Fixed deformities require arthrodesis of one or several joint-lines in the hindfoot; for the ankle, total replacement after realignment of the foot, or tibiotalocalcaneal fusion or ankle and hindfoot fusion; and, for the midfoot, cuneonavicular or cuneometatarsal fusion. Tendinous procedures are often associated. Specific etiologies may need individualized procedures. In conclusion, adult flatfoot tends to be diagnosed and managed too late, with consequent impact on the ankle, the management of which is complex and poorly codified. PMID:25595429

  1. State Standards: Authenticity vs. Diversity.

    Science.gov (United States)

    Davidson, Marcia R.; Howell, Kenneth W.

    1997-01-01

    Reviews problems with the current movement to use national standards and performance assessment to reform education and the impact of the standards on students with disabilities. The characteristics of standards, as they are currently being employed, are discussed, along with issues related to measurement, reliability, and validity. (Author/CR)

  2. Intra-rater reproducibility and validity of Nintendo Wii Balance Tests in community-dwelling Older Adults

    DEFF Research Database (Denmark)

    Jørgensen, Martin; Læssøe, Uffe; Hendriksen, C;

    2014-01-01

    The aims of the current study were to examine the intrarater intersession reproducibility of the Nintendo Wii agility and stillness tests and explore the concurrent validity in relation to gold-standard force-plate analysis. Within-day intersession reproducibility was examined in 30 older adults...... a low-cost, objective, reproducible, and valid test of undisturbed postural balance in community-dwelling older adults....

  3. Current Situation of Standardization of Engineering Risk Management and Development Trend in China%风险管理标准现状及我国工程风险管理标准化发展趋势

    Institute of Scientific and Technical Information of China (English)

    张辉

    2014-01-01

    The quality and safety risk have been at a more and more high level in engineering construction.The economic development and social stability are affected by the key factor of high frequency accidents now;therefore,in order to realize pre-control and management of quality and safety risk management of engineering construction actively,a normal risk management system should be established.According to the current situa-tion analysis of risk management in engineering construction of Australia & New Zealand,England,Interna-tional Standardization Organization and China,the main contents,structure system,rating criterion,applica-tion scope,key points and the difference among the different standards are discussed.The analysis and discus-sion results will provide some guide and reference to establish the system and consummate the technical stand-ards for risk management standardization of the engineering construction in China to some extent.Moreover, the development trend of risk management standardization in engineering construction field is discussed;and some suggestion on the development trend and main tasks of risk management standardization are proposed.%随着我国城镇化发展的进一步推进,工程建设质量安全风险越来越高,工程风险事件频发已经成为制约我国经济建设可持续发展和社会稳定的关键因素,因此,有必要通过系统化、标准化、规范化的风险管理标准体系,实现“主动控制、主动管理”建设工程的施工质量安全风险。本文通过对澳大利亚/新西兰、英国、国际标准化组织以及我国的工程相关风险管理标准现状分析,探讨了各国风险管理标准的主要内容、结构体系、等级标准、适用范围、主要特点及不同之处,为我国工程建设风险管理标准体系的构建、相关技术标准的完善提供一定的借鉴和参考。同时,本文探讨了我国工程建设领域的风险管理标准化发展趋势

  4. The Change Idea of Virtual Learning Tools Standards Development:Current Situation and System Framework%变革理念下虚拟学具标准研制现状梳理与体系框架*

    Institute of Scientific and Technical Information of China (English)

    郁晓华; 雷云鹤; 祝智庭; 吴永和

    2013-01-01

    As a new term in the new round of e-Schoolbags development, virtual learning tools merge the concepts of learning toolkits and learning instruments. The standards of virtual learning tools are important technical support and security guidance for its industrial development and educational practice. Current developments of virtual learning tools follows the models and ideas of traditional teaching, so learners still do not enjoy sufficient autonomy and freedom during the interaction with the learning tools. New learning forms and technologies require to change the development concept and concentrate on user experience, which are more intelligent, open and personalized, and establish an active service mechanism of being process-oriented, activity-sensitive even content-sensitive. Guided by the changing idea, an analysis is made among the needs and problems of the standards stakeholders. The entire standard framework of virtual learning tools is proposed, including classification standard, description standard, configuration specification, polymerization specification and evaluation standard.%  虚拟学具是电子书包新一轮发展所引入的一个全新概念,是学具和学习工具二者发展的集合体,其标准的研制是指导虚拟学具领域产业发展和教育实践的重要技术支持和保障。目前虚拟学具的发展表现的都是一种传统教学模式和观念的延续,学习者在与虚拟学具互动的过程中并没有获得足够的自主权和自由度。学习形态和新技术的发展要求虚拟学具变革发展理念,以用户体验为中心,趋于更加智能、开放、个性化,建立一种过程导向、活动敏感甚至内容敏感的主动服务机制。在这种变革理念指导下分析虚拟学具标准各利益相关人员的需求与问题,得出虚拟学具标准的内容体系包括虚拟学具分类标准、虚拟学具描述标准、虚拟学具配置规范、虚拟学具聚合规范和虚

  5. Standardizing visual display quality

    NARCIS (Netherlands)

    Besuijen, Ko; Spenkelink, Gerd P.J.

    1998-01-01

    The current ISO 9241–3 standard for visual display quality and the proposed user performance tests are reviewed. The standard is found to be more engineering than ergonomic and problems with system configuration, software applications, display settings, user behaviour, wear and physical environment

  6. The Genomic Standards Consortium

    DEFF Research Database (Denmark)

    Field, Dawn; Amaral-Zettler, Linda; Cochrane, Guy;

    2011-01-01

    Standards Consortium (GSC), an open-membership organization that drives community-based standardization activities, Here we provide a short history of the GSC, provide an overview of its range of current activities, and make a call for the scientific community to join forces to improve the quality...

  7. Study on Current Condition and Sustainable Development of Adult Education%成人教育现状及可持续发展的研究——以喀什师范学院成人教育学院为例

    Institute of Scientific and Technical Information of China (English)

    方志刚; 戚甫娟; 赛买提·吐尔逊; 刘江

    2011-01-01

    近年来,全国成人学历教育生源呈现逐渐萎缩的趋势,其生存与发展受到了严峻的挑战.如何在困境中实现科学发展,是当今高校成人教育面临的一大课题.从办学规模、学历结构、民族成份情况、学员特点及专业结构等角度,分析了我院成人教育的现状,指出存在的问题,并结合实际提出了实现我院成人教育可持续发展的对策.%Adult students of academic education from all over country showed the trend of shrinking gradually in recent years,the fact that the development and survival of adult academic education has been a severe challenge.How to realize the scientific development in times of hardship has become a large subject for current adult education of college.In this paper,the development of adult education of our college in the past decade as an example,the school size,academic structure,ethnic composition of the situation,characteristics and professional structure of students will be analysised the current situation and characteristics of academic education in this paper;it also be analysised the non academic current education on the basis of learning from adult academic education at the same time,the main problems of adult education will be found in this paper,the sustainable development strategies of adult education are proposed according to the actual conditions of our college.

  8. Photometric Standards for Non-Standard Filters

    Science.gov (United States)

    Hoot, John E.

    2015-05-01

    The AAVSO, professional collaborators, and research consortiums are increasingly requesting that photometric observations be submitted after they have been transformed onto 'standard' photometric systems. This greatly reduces the burden on the principal investigators in managing and merging data from many disparate contributors, but discourages many potential contributors who are unaware that their present equipment can make a valuable contribution. Many potential observers, amateurs, students and instructors are confused over what filters are required and what standards are best. This paper focuses on the best standards and observation methods for observers with one shot color cameras and those possessing monochrome CCD cameras with LRGB filter sets, the two most common configurations used in amateur and educational observatories. This paper examines which current standards best match common equipment and present effective ways for amateurs and students to reduce data to standard systems with common tools and a minimum of mathematical rigor.

  9. Children Grow Up: Autism in Adolescents & Adults.

    Science.gov (United States)

    Meyers, Kathleen; Griesman, Brenda

    The booklet examines issues associated with autism in adolescents and adults. Teenagers with autism exhibit behaviors not unlike their nondisabled peers, and standard definitions of the syndrome may not be relevant at that age. Brief articles explore the range of emotions families may encounter with a young adult or adult who has autism, typical…

  10. Craniospinal radiotherapy in adult medulloblastoma

    Energy Technology Data Exchange (ETDEWEB)

    Selek, U.; Zorlu, F.; Hurmuz, P.; Cengiz, M.; Gurkaynak, M. [Hacettepe Univ., Ankara (Turkey). Dept. of Radiation Oncology; Turker, A. [Hacettepe Univ., Ankara (Turkey). Dept. of Internal Medicine; Soylemezoglu, F. [Hacettepe Univ., Ankara (Turkey). Dept. of Pathology

    2007-05-15

    Purpose: To evaluate the outcome and prognostic factors of adult patients with medulloblastoma. Patients and Methods: 26 adult medulloblastoma patients with a median age of 27 were subjected to craniospinal radiotherapy. A dose of 30.6 Gy with 1.8 Gy/fraction/day was prescribed to M0 patients, while 36 Gy were to be applied in patients with positive cerebrospinal liquor findings. The posterior fossa was boosted to 54 Gy. While 20 patients underwent external-beam radiotherapy alone, only six received sequential adjuvant chemotherapy. Results: Male/female ratio was 1.2. Preradiotherapy Karnofsky performance status was recorded as median 100%. 50% were classified as poor risk (n = 10, subtotal resection; n = 3, M+). The median follow-up time was 46.5 months. The 5-year actuarial survival rates for recurrence-free, distant metastasis-free, disease-free, and overall survival were 82.5%, 90.8%, 73.5%, and 89.7%, respectively. Patient characteristics, treatment factors and tumor characteristics failed to show any significance in univariate analysis. Grade 3 or 4 late morbidities were not observed. Conclusion: Yet, the current standard of care seems to remain craniospinal irradiation after maximal surgical resection of the primary neoplasm without clear indications for adjuvant chemotherapy. (orig.)

  11. DOE technical standards list: Department of Energy standards index

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-06-01

    This technical standards list (TSL) was prepared for use by personnel involved in the selection and use of US DOE technical standards and other government and non-government standards. This TSL provides listings of current DOE technical standards, non-government standards that have been adopted by DOE, other government documents in which DOE has a recorded interest, and cancelled DOE technical standards. Standards are indexed by type in the appendices to this document. Definitions of and general guidance for the use of standards are also provided.

  12. Clinical Interviewing with Older Adults

    Science.gov (United States)

    Mohlman, Jan; Sirota, Karen Gainer; Papp, Laszlo A.; Staples, Alison M.; King, Arlene; Gorenstein, Ethan E.

    2012-01-01

    Over the next few decades the older adult population will increase dramatically, and prevalence rates of psychiatric disorders are also expected to increase in the elderly cohort. These demographic projections highlight the need for diagnostic instruments and methods that are specifically tailored to older adults. The current paper discusses the…

  13. Differences Analysis Between New and Old Standard IEC 61008-1 for Residual Current Operated Circuit-Breakers%剩余电流动作断路器IEC 61008-1新旧标准差异分析

    Institute of Scientific and Technical Information of China (English)

    何秀明

    2013-01-01

    The article introduced the revision situation of IEC 61008-1: 2012 (edition 3.1) for the residual current operated circuit-breakers (RCCBs) without integral overcurrent protection for household and similar uses, comparing with IEC 61008-1:1996 (edition 2.0) and IEC 61008-1:1996 am1(2002) and analyzing the differences about the scope, terms and definition, characteristics, marking, standard working conditions, construction and operation requirement, tests and annexes, so as to provide references for the corresponding technical personnel.%  介绍了家用和类似用途的不带过电流保护的剩余电流动作断路器(RCCB)IEC 61008-1:2012(3.1版)的修订情况,并与IEC 61008-1:1996(2.0版)及IEC 61008-1:1996 am1(2002)进行了比较,分析了新旧标准在范围、术语和定语、特性、标志、标准工作条件、结构和操作的要求、试验及附录等方面的差异,供相关技术人员进行参考.

  14. The Questions Of Current Institutions Accounting Standards and the Improved Measures%现行事业单位会计准则存在的问题及改进措施

    Institute of Scientific and Technical Information of China (English)

    王嘉军

    2009-01-01

    As continuous development of market economy, the business of Chinese various economic organizations has undergone great changes, thus requirements to accounting have changed. The defects of current Institutions accountancy standard is a main reason of reformation to institutions accountancy. There are some significances to the improvement of institution accouting work and promotion of the de-velopment to institution accouting field.%随着市场经济的不断发展,我国各经济组织的业务发生了很大的变化,对会计活动提出新的要求.现行事业单位会计准则制度本身存在的缺陷是事业单位会计改革的主要原因.改进事业单位的会计工作,对促进事业单位会计工作的发展具有一定的意义.

  15. Standard NIM instrumentation system

    CERN Document Server

    1990-01-01

    NIM is a standard modular instrumentation system that is in wide use throughout the world. As the NIM system developed and accommodations were made to a dynamic instrumentation field and a rapidly advancing technology, additions, revisions and clarifications were made. These were incorporated into the standard in the form of addenda and errata. This standard is a revision of the NIM document, AEC Report TID- 20893 (Rev 4) dated July 1974. It includes all the addenda and errata items that were previously issued as well as numerous additional items to make the standard current with modern technology and manufacturing practice.

  16. Standard NIM instrumentation system

    Energy Technology Data Exchange (ETDEWEB)

    1990-05-01

    NIM is a standard modular instrumentation system that is in wide use throughout the world. As the NIM system developed and accommodations were made to a dynamic instrumentation field and a rapidly advancing technology, additions, revisions and clarifications were made. These were incorporated into the standard in the form of addenda and errata. This standard is a revision of the NIM document, AEC Report TID-20893 (Rev. 4) dated July 1974. It includes all the addenda and errata items that were previously issued as well as numerous additional items to make the standard current with modern technology and manufacturing practice.

  17. Standard NIM instrumentation system

    International Nuclear Information System (INIS)

    NIM is a standard modular instrumentation system that is in wide use throughout the world. As the NIM system developed and accommodations were made to a dynamic instrumentation field and a rapidly advancing technology, additions, revisions and clarifications were made. These were incorporated into the standard in the form of addenda and errata. This standard is a revision of the NIM document, AEC Report TID-20893 (Rev. 4) dated July 1974. It includes all the addenda and errata items that were previously issued as well as numerous additional items to make the standard current with modern technology and manufacturing practice

  18. Accounting standards

    NARCIS (Netherlands)

    B. Stellinga

    2014-01-01

    The European and global regulation of accounting standards have witnessed remarkable changes over the past twenty years. In the early 1990s, EU accounting practices were fragmented along national lines and US accounting standards were the de facto global standards. Since 2005, all EU listed companie

  19. Adult medulloblastoma.

    OpenAIRE

    Pobereskin, L; Treip, C

    1986-01-01

    Twelve cases of adult onset medulloblastoma are presented. Clinical features, treatment and outcome are discussed. It was found that the survival rates for adults are no better than for children. There were no clinical or histological features that distinguished these tumours from those occurring in childhood, except for a higher incidence of hemisphere lesions.

  20. The Sonoma Water Evaluation Trial (SWET): A randomized drinking water intervention trial to reduce gastrointestinal illness in older adults

    Science.gov (United States)

    Objectives. We estimate the risk of highly credible gastrointestinal illness (HCGI) among adults 55 and older in a community drinking tap water meeting current U.S. standards. Methods. We conducted a randomized, triple-blinded, crossover trial in 714 households (988 indiv...

  1. Qualidade do ar em ambientes internos hospitalares: estudo de caso e análise crítica dos padrões atuais Indoor air quality in hospitals: a case study and a critical review of current standards

    Directory of Open Access Journals (Sweden)

    Marina Eller Quadros

    2009-09-01

    Full Text Available O objetivo deste trabalho foi avaliar a qualidade do ar em três categorias de ambientes hospitalares: unidade de terapia intensiva (UTI adulto, UTI neonatal (UTN e centro cirúrgico de um hospital em Florianópolis, Brasil. Avaliaram-se a concentração de dióxido de carbono, a vazão e renovação de ar nas salas do centro cirúrgico. A concentração de bioaerossóis foi estimada em um dia de avaliação para cada ambiente. Não se observou relação entre a concentração de bioaerossóis e o tempo de uso das salas de cirurgia. A concentração média de bioaerossóis foi de 231 UFC.m-3 para fungos e de 187 UFC.m-3 para bactérias. Os ambientes avaliados atendiam aos valores recomendados pela legislação vigente. Os resultados permitiram avaliar criticamente essa legislação e apresentar sugestões para estabelecimento de uma resolução específica para ambientes hospitalares no Brasil.The objective of this paper was to evaluate the air quality in three indoor hospital environments: a neonatal intensive care unit (ICU, an adult ICU and a surgical ward of a hospital in Florianópolis, Brazil. Carbon dioxide concentrations, exchange air flow rates as well as fungi and bacteria concentrations were measured in these rooms. Bioaerosol concentrations were evaluated throughout one-work day for each operating room. No relationship was observed between bioaerosol concentration and the period of use in the surgical ward. Average bioaerosol concentrations were of 231 UFC.m-3 for filamentous fungi and 187 UFC.m-3 for bacteria. All environments evaluated were, overall, in compliance with current legislations. Results allowed a critical review of the present regulations and suggestions for the establishment of a specific regulation for hospital environments in Brazil.

  2. Current Situation and Analysis of Body Composition of Adults in Shanghai,2010%2010年上海市成年人身体成分现状与分析

    Institute of Scientific and Technical Information of China (English)

    陈千红; 王人卫

    2014-01-01

    目的:分析上海市成年人身体成分的现状并提出改善对策。方法:基于2010年国民体质监测的上海市18个区县2059岁成年人,共29322名,其中男性14562名,女性14760名。选取反应身体成分的测试指标及其派生指标。采用独立样本t检验,分析各指标不同年龄段及性别间的差异;选取问卷调查数据中的部分指标(如年龄段、性别、职业、受教育程度、所在单位是否有体育锻炼补贴等),采用二元logistic回归,分析除体力活动和饮食行为以外影响肥胖的因素。结果:上海市成年人身体成分多数指标随年龄增长而增长。超重和肥胖检出率分别为30�3%、8�5%,其中男性分别为38�2%、11�0%,女性分别为22�5%、6�1%;中心性肥胖率为42�7%,其中男性为49�9%,女性为35�7%;超重率与2005年相比降低了0�5个百分点,肥胖率增长了1�4个百分点。年龄段、性别、受教育程度、职业、所在工作场所是否有公共体育场地设施、居住地点离工作场所的距离、是否经常熬夜和日睡眠时间可能是肥胖的影响因素。结论:上海市成年人超重和肥胖率较高,且肥胖率十年间呈现持续增长趋势。肥胖是多因素导致的疾病,肥胖的防治工作应采取有效的综合性措施。%Purpose:To analyze the current body composi-tion of adults in Shanghai and propose improvement meas-ures. Method:Based on the data set of 2010 National Phy-sique Monitoring in Shanghai, including 18 districts or counties,of which 29322 adults aged 20 59(14562 men and 14760 women ) were chosen. Then indicators about body composition and their derived indicators were ana-lyzed using independent sample t-test for their age and gender differences;in addition to physical inactivity and unhealthy diet,the possible contributing factors of obesity in the survey data(age,sex,occupation,education level, the

  3. Quality measurement of semantic standards

    OpenAIRE

    Folmer, E.J.A.; Oude Luttighuis, P.H.W.M.; Hillegersberg, van, R.

    2010-01-01

    Quality of semantic standards is unadressed in current research while there is an explicit need from standard developers. The business importance is evident since quality of standards will have impact on its diffusion and achieved interoperability in practice. An instrument to measure the quality of semantic standards is designed to contribute to the knowledge domain, standards developers and might ultimo lead to improved interoperability. This instrument is iteratively designed with multiple...

  4. Adult and lifelong education

    DEFF Research Database (Denmark)

    Milana, Marcella; Holford, John; Mohorčič Špolar, Vida

    2014-01-01

    The contributions published in this special issue of Globalisation, Societies and Education draw from an international conference “Trans-nationalization of Educational Policy Making: Implications for Adult and Lifelong Learning”, held in Nottingham on 10-12 February 2012. The conference was organ......The contributions published in this special issue of Globalisation, Societies and Education draw from an international conference “Trans-nationalization of Educational Policy Making: Implications for Adult and Lifelong Learning”, held in Nottingham on 10-12 February 2012. The conference...... was organised by the Research Network on Policy Studies on Adult Education, established under the auspices of the European Society for the Research on the Education of Adults (ESREA). The aim of the conference was to explore how globalisation affects agency and policy processes in the area of adult and lifelong...... education, and the conditions or structures under which policy processes occur. The objective was to deepen understanding of how scientific inquiry – as a means of comprehending and interpreting current processes and their implications – can accompany and support contemporary developments in adult...

  5. Adult growth hormone deficiency

    OpenAIRE

    Vishal Gupta

    2011-01-01

    Adult growth hormone deficiency (AGHD) is being recognized increasingly and has been thought to be associated with premature mortality. Pituitary tumors are the commonest cause for AGHD. Growth hormone deficiency (GHD) has been associated with neuropsychiatric-cognitive, cardiovascular, neuromuscular, metabolic, and skeletal abnormalities. Most of these can be reversed with growth hormone therapy. The insulin tolerance test still remains the gold standard dynamic test to diagnose AGHD. Growth...

  6. Tuberculosis in Older Adults.

    Science.gov (United States)

    Rajagopalan, Shobita

    2016-08-01

    Tuberculosis (TB) remains one of the world's most lethal infectious diseases. Preventive and control strategies among other high-risk groups, such as the elderly population, continues to be a challenge. Clinical features of TB in older adults may be atypical and confused with age-related diseases. Diagnosis and management of TB in the elderly person can be difficult; treatment can be associated with adverse drug reactions. This article reviews the current global epidemiology, pathogenesis, clinical characteristics, diagnosis, management, and prevention of Mycobacterium tuberculosis infection in community-dwelling and institutionalized aging adults. PMID:27394018

  7. Standardization of depression measurement

    DEFF Research Database (Denmark)

    Wahl, Inka; Löwe, Bernd; Bjørner, Jakob;

    2014-01-01

    OBJECTIVES: To provide a standardized metric for the assessment of depression severity to enable comparability among results of established depression measures. STUDY DESIGN AND SETTING: A common metric for 11 depression questionnaires was developed applying item response theory (IRT) methods. Data...... of 33,844 adults were used for secondary analysis including routine assessments of 23,817 in- and outpatients with mental and/or medical conditions (46% with depressive disorders) and a general population sample of 10,027 randomly selected participants from three representative German household surveys....... RESULTS: A standardized metric for depression severity was defined by 143 items, and scores were normed to a general population mean of 50 (standard deviation = 10) for easy interpretability. It covers the entire range of depression severity assessed by established instruments. The metric allows...

  8. Adult neurology training during child neurology residency.

    Science.gov (United States)

    Schor, Nina F

    2012-08-21

    As it is currently configured, completion of child neurology residency requires performance of 12 months of training in adult neurology. Exploration of whether or not this duration of training in adult neurology is appropriate for what child neurology is today must take into account the initial reasons for this requirement and the goals of adult neurology training during child neurology residency.

  9. Critical Discourse Analysis, Adult Education and "Fitba"

    Science.gov (United States)

    Player, John

    2013-01-01

    In this article I will use an example of current adult education practice, the Glory and Dismay Football Literacies Programme (GDFLP) to appraise the value of critical discourse analysis (CDA) for adult learners, both individually and collectively, and for adult education practitioners with an interest in developing critical literacy skills. The…

  10. Communications standards

    CERN Document Server

    Stokes, A V

    1986-01-01

    Communications Standards deals with the standardization of computer communication networks. This book examines the types of local area networks (LANs) that have been developed and looks at some of the relevant protocols in more detail. The work of Project 802 is briefly discussed, along with a protocol which has developed from one of the LAN standards and is now a de facto standard in one particular area, namely the Manufacturing Automation Protocol (MAP). Factors that affect the usage of networks, such as network management and security, are also considered. This book is divided into three se

  11. Achieving Standardization

    DEFF Research Database (Denmark)

    Henningsson, Stefan

    2016-01-01

    competitive, national customs and regional economic organizations are seeking to establish a standardized solution for digital reporting of customs data. However, standardization has proven hard to achieve in the socio-technical e-Customs solution. In this chapter, the authors identify and describe what has...... to be harmonized in order for a global company to perceive e-Customs as standardized. In doing so, they contribute an explanation of the challenges associated with using a standardization mechanism for harmonizing socio-technical information systems....

  12. Achieving Standardization

    DEFF Research Database (Denmark)

    Henningsson, Stefan

    2014-01-01

    competitive, national customs and regional economic organizations are seeking to establish a standardized solution for digital reporting of customs data. However, standardization has proven hard to achieve in the socio-technical e-Customs solution. In this chapter, the authors identify and describe what has...... to be harmonized in order for a global company to perceive e-Customs as standardized. In doing so, they contribute an explanation of the challenges associated with using a standardization mechanism for harmonizing socio-technical information systems....

  13. Adult Strabismus

    Science.gov (United States)

    ... will likely improve the double vision and depth perception. Also, strabismus affects adults in emotional, social, and ... muscle surgery is usually not severe. Headache, pulling sensation with eye movement and foreign body sensation in ...

  14. Hypertension in young adults.

    Science.gov (United States)

    De Venecia, Toni; Lu, Marvin; Figueredo, Vincent M

    2016-01-01

    Hypertension remains a major societal problem affecting 76 million, or approximately one third, of US adults. While more prevalent in the older population, an increasing incidence in the younger population, including athletes, is being observed. Active individuals, like the young and athletes, are viewed as free of diseases such as hypertension. However, the increased prevalence of traditional risk factors in the young, including obesity, diabetes mellitus, and renal disease, increase the risk of developing hypertension in younger adults. Psychosocial factors may also be contributing factors to the increasing incidence of hypertension in the younger population. Increased left ventricular wall thickness and mass are increasingly found in young adults on routine echocardiograms and predict future cardiovascular events. This increasing incidence of hypertension in the young calls for early surveillance and prompt treatment to prevent future cardiac events. In this review we present the current epidemiological data, potential mechanisms, clinical implications, and treatment of hypertension in young patients and athletes.

  15. Quality measurement of semantic standards

    NARCIS (Netherlands)

    Folmer, E.J.A.; Oude Luttighuis, P.H.W.M.; Hillegersberg, J. van

    2010-01-01

    Quality of semantic standards is unadressed in current research while there is an explicit need from standard developers. The business importance is evident since quality of standards will have impact on its diffusion and achieved interoperability in practice. An instrument to measure the quality of

  16. ISO radiation sterilization standards

    International Nuclear Information System (INIS)

    This presentation provides an overview of the current status of the ISO radiation sterilization standards. The ISO standards are voluntary standards which detail both the validation and routine control of the sterilization process. ISO 11137 was approved in 1994 and published in 1995. When reviewing the standard you will note that less than 20% of the standard is devoted to requirements and the remainder is guidance on how to comply with the requirements. Future standards developments in radiation sterilization are being focused on providing additional guidance. The guidance that is currently provided in informative annexes of ISO 11137 includes: device/packaging materials, dose setting methods, and dosimeters and dose measurement, currently, there are four Technical Reports being developed to provide additional guidance: 1. AAMI Draft TIR, 'Radiation Sterilization Material Qualification' 2. ISO TR 13409-1996, 'Sterilization of health care products - Radiation sterilization - Substantiation of 25 kGy as a sterilization dose for small or infrequent production batches' 3. ISO Draft TR, 'Sterilization of health care products - Radiation sterilization Selection of a sterilization dose for a single production batch' 4. ISO Draft TR, 'Sterilization of health care products - Radiation sterilization-Product Families, Plans for Sampling and Frequency of Dose Audits'

  17. 碘盐浓度调整对芜湖市居民碘营养水平的影响%Current iodine nutritional status in population in Wuhu City after implementation of the new iodized salt concentration standard

    Institute of Scientific and Technical Information of China (English)

    崔春; 虞晨; 陈勇; 张焱

    2015-01-01

    目的:了解新标准碘盐供应对芜湖市居民碘营养状况的影响,为今后调整碘盐浓度提供依据。方法调查2011~2014年碘盐浓度调整前后芜湖市8个县(区)儿童、孕妇碘营养状况以及芜湖市居民食用盐状况。盐碘检测采用直接滴定法,川盐及其他强化食用盐采用仲裁法(GB/T 13025.7-1999);尿碘检测采用砷铈催化分光光度方法(WS/T 107-2006)。结果芜湖市2011~2014年分别采集食盐1968份、2280份、2340份、2280份;检测碘盐中位数分别为30.85mg/kg、26.79mg/kg、24.2mg/kg、23.3mg/kg;8~10岁儿童尿碘中位数分别为283.33μg/L、269.02μg/L、240.23μg/L、207.54μg/L;2012~2014年孕妇尿碘中位数分别为208.8μg/L、193.02μg/L、163.6μg/L。结论新标准碘盐满足了8~10岁儿童碘营养需求,但是孕妇存在碘营养不足的危险,需要加强对孕妇健康教育,提高孕妇补碘意识。%Objective To investigate the current iodine nutritional status in population in Wuhu City after practice of the new iodized salt concentration standard for scientific basis to accurately rectify the iodine supplementation in table salt. Methods Iodine nutrition status and dietary intake of salt were surveyed in chil⁃dren and pregnant women as well as civilians in 8 counties/districts in Wuhu City from 2011 to 2014. The salt iodine concentration was measured by direct titration technique, and the chuan salt and other fortified salt were tested by the method of arbitration (GB/T 13025.7-1999). Urinary iodine was determined with arsenic-ceri⁃um catalytic spectrophotometry (WS/T 107-2006). Results A total of 1968, 2280, 2340 and 2280 samples were respectively collected from 2011 to 2014, and corresponding median of salt iodine was 30.85mg/kg, 26.79mg/kg, 24.2mg/kg and 23.3mg/kg. The median of urinary iodine was 283.33μg/L,269.02μg/L, 240.23μg/L and 207.54μg/L, respectively for children aged between 8 and 10 years, and 208.8

  18. Spin current

    CERN Document Server

    Valenzuela, Sergio O; Saitoh, Eiji; Kimura, Takashi

    2012-01-01

    In a new branch of physics and technology called spin-electronics or spintronics, the flow of electrical charge (usual current) as well as the flow of electron spin, the so-called 'spin current', are manipulated and controlled together. This book provides an introduction and guide to the new physics and application of spin current.

  19. Transition experiences and health care utilization among young adults with type 1 diabetes

    Directory of Open Access Journals (Sweden)

    Garvey KC

    2013-08-01

    -thirds (66% reported receiving all recommended diabetes screening tests in the previous year, with no difference according to provider type. Conclusion: In this sample, transition preparation was variable and one quarter reported gaps in obtaining adult diabetes care. Nevertheless, the majority endorsed currently receiving regular diabetes care, although visit frequency differed by provider type. Because locating patients after transition was incomplete, our findings suggest the need for standardized methods to track transitioning patients. Keywords: type 1 diabetes mellitus, health care delivery, young adults, transition to adult care

  20. EOS standards

    Energy Technology Data Exchange (ETDEWEB)

    Greeff, Carl W [Los Alamos National Laboratory

    2011-01-12

    An approach to creating accurate EOS for pressure standards is described. Applications to Cu, Au, and Ta are shown. Extension of the method to high compressions using DFT is illustrated. Comparisons with modern functionals show promise.

  1. (Terminology standardization)

    Energy Technology Data Exchange (ETDEWEB)

    Strehlow, R.A.

    1990-10-19

    Terminological requirements in information management was but one of the principal themes of the 2nd Congress on Terminology and Knowledge Engineering. The traveler represented the American Society for Testing and Materials' Committee on Terminology, of which he is the Chair. The traveler's invited workshop emphasized terminology standardization requirements in databases of material properties as well as practical terminology standardizing methods. The congress included six workshops in addition to approximately 82 lectures and papers from terminologists, artificial intelligence practitioners, and subject specialists from 18 countries. There were approximately 292 registrants from 33 countries who participated in the congress. The congress topics were broad. Examples were the increasing use of International Standards Organization (ISO) Standards in legislated systems such as the USSR Automated Data Bank of Standardized Terminology, the enhanced Physics Training Program based on terminology standardization in Physics in the Chinese province of Inner Mongolia, and the technical concept dictionary being developed at the Japan Electronic Dictionary Research Institute, which is considered to be the key to advanced artificial intelligence applications. The more usual roles of terminology work in the areas of machine translation. indexing protocols, knowledge theory, and data transfer in several subject specialties were also addressed, along with numerous special language terminology areas.

  2. Pathways of Knowing: Integrating Citizen Science and Critical Thinking in the Adult ELL Classroom

    Science.gov (United States)

    Basham, Melody

    This action research study examines what common perceptions and constructs currently exist in educating adult immigrants in Arizona and considers how might the integration of citizen science with the current English curriculum promote higher order thinking and educational equity in this population. A citizen science project called the Mastodon Matrix Project was introduced to a Level 2 ELAA (English Language Acquisition for Adults) classroom and aligned with the Arizona Adult Standards for ELAA education. Pre and post attitudinal surveys, level tests, and personal meaning maps were implemented to assess student attitudes towards science, views on technology, English skills, and knowledge gained as a result of doing citizen science over a period of 8 weeks.

  3. 试论现行财务会计与报表的缺陷及改进--从企业会计准则(基本准则)的缺陷谈起%On the Defects and Improvement of Current Financial Accounting and Reporting---from the defects of the enterprise accounting standards (basic standards)

    Institute of Scientific and Technical Information of China (English)

    曹苏铁

    2016-01-01

    China's current enterprise accounting standards - Basic Standards in accounting and accounting elements of the division, the statement of accounting measurement, as well as the understanding and use of the accrual basis, all exist obvious defects. This paper analyzes the defects of the above mentioned defects, and puts forward care his own opinion 1. Do not put“sustainable management”set a foundation for enterprise accounting; 2. The profit should not be included in the accounting elements as the basic classification of accounting; 3. Enterprises in the initial measurement of the accounting elements shall, in general, use the fair value, and surviving measurement is usually follow the historical cost principle; 4. Responsibilities occurred receipt and payment system and implementation system is not “either/or” antagonistic relationship; 5. The traditional income statement can be adapted as income and expenditure.%我国现行企业会计准则—基本准则在会计假设和会计要素划分,对会计计量的表述,以及对权责发生制的理解与运用方面存在着明显的缺陷.本文逐一分析了上述缺陷条款的不妥当之处,并提出了自己的见解:1.不能把“持续经营”设定为企业会计核算的基础;2.利润不应当作为会计的基本分类列入会计要素;3.企业在对会计要素进行初始计量时一般采用公允价值,而存续计量则通常遵照历史成本原则;4.权责发生制与收付实现制不是“非此即彼”的对立关系;5.传统利润表可以改编为新的收入支出表.

  4. Childhood dyspraxia predicts adult-onset nonaffective-psychosis-spectrum disorder

    DEFF Research Database (Denmark)

    Schiffman, Jason; Mittal, Vijay; Kline, Emily;

    2015-01-01

    Several neurological variables have been investigated as premorbid biomarkers of vulnerability for schizophrenia and other related disorders. The current study examined whether childhood dyspraxia predicted later adult nonaffective-psychosis-spectrum disorders. From a standardized neurological...... showed higher scores on the dyspraxia scale predict nonaffective-psychosis-spectrum disorders relative to other psychiatric disorders and no mental illness outcomes, even after controlling for genetic risk, χ2 (4, 244) = 18.61, p ... abnormalities spanning functionally distinct brain networks) specifically predict adult nonaffective-psychosis-spectrum disorders are consistent with a theory of abnormal connectivity, and they highlight a marked early-stage vulnerability in the pathophysiology of nonaffective-psychosis-spectrum disorders....

  5. Globalization of HVDC Standards

    Institute of Scientific and Technical Information of China (English)

    Gu Chen

    2011-01-01

    China has made outstanding achievements in the fields of Ultra-High Voltage Direct Current (UHV DC) power transmission and security of large-scale power grid till now,and the smart grid construction has been under way,all of which put forward much higher strategic requirements of standards globalization.

  6. Fasteners 5 basic standards

    CERN Document Server

    2011-01-01

    This 3rd edition of DIN Handbook 193 contains 38 fundamental standards on fasteners, covering such areas as countersinks and counterbores, widths across flats, thread run-outs and thread undercuts, bolt and screw ends, stud ends and tapped holes for compression couplings, driving features, tolerances for screw threads and nomenclature. New to this compilation are DIN 34824 dealing with 12 point sockets for bolts and screws and DIN EN ISO 15065 which reflects current practice in Europe with regard to countersinks for countersunk head screws. Also included for the first time is DIN EN ISO 225 "Fasteners - Bolts, screws, studs and nuts - Symbols and descriptions of dimensions" which, together with DIN ISO 1891, now also incorporates terminology in Chinese, Japanese and Swedish. Four standards have been revised for this edition, among them DIN 918 Supplement 3 which provides information on the current status of European standardization relating to fasteners. DIN Handbook 193 is one of a series of six handbooks on...

  7. Automated Standard Hazard Tool

    Science.gov (United States)

    Stebler, Shane

    2014-01-01

    The current system used to generate standard hazard reports is considered cumbersome and iterative. This study defines a structure for this system's process in a clear, algorithmic way so that standard hazard reports and basic hazard analysis may be completed using a centralized, web-based computer application. To accomplish this task, a test server is used to host a prototype of the tool during development. The prototype is configured to easily integrate into NASA's current server systems with minimal alteration. Additionally, the tool is easily updated and provides NASA with a system that may grow to accommodate future requirements and possibly, different applications. Results of this project's success are outlined in positive, subjective reviews complete by payload providers and NASA Safety and Mission Assurance personnel. Ideally, this prototype will increase interest in the concept of standard hazard automation and lead to the full-scale production of a user-ready application.

  8. CPR: Adult

    Medline Plus

    Full Text Available Refresher Center Home FIRST AID, CPR and AED LIFEGUARDING Refresher Putting It All Together: CPR—Adult (2:03) Refresher videos only utilize this player QUICK LINKS Home RedCross.org Purchase Course Materials Shop Our Store ...

  9. Measurement system of high voltage and high current measurements at INMETRO - Brazilian Institute for Metrology, Standardization and Industrial Quality; Sistema de medicao de alta tensao e alta corrente do INMETRO - Brasil

    Energy Technology Data Exchange (ETDEWEB)

    Vitorio, Patricia Cals de O.; Franca, Ademir Martins de; Soares, Marco Aurelio; Pereira, Luiz Napoleao; Costa, Danielli Guimaraes; Moreira, Giselle Cobica; Nascimento, Paulo Roberto Mesquita [Instituto Nacional de Metrologia, Normalizacao e Qualidade Industrial (DIMCI/INMETRO), Duque de Caxias, RJ (Brazil). Diretoria de Metrologia Cientifica e Industrial], E-mail: latra@inmetro.gov.br

    2009-07-01

    This work presents the basic characteristics and uncertainties of the calibration equipment in high voltage and high current available at the INMETRO: system of measurement in alternating high voltage up to 200 kV, system of measurement in alternating current up to 2 k A, and system of measurement in continuous high voltage up to 150 kV.

  10. Status of conversion of NE standards to national consensus standards

    International Nuclear Information System (INIS)

    One major goal of the Nuclear Standards Program is to convert existing NE standards into national consensus standards (where possible). This means that an NE standard in the same subject area using the national consensus process. This report is a summary of the activities that have evolved to effect conversion of NE standards to national consensus standards, and the status of current conversion activities. In some cases, all requirements in an NE standard will not be incorporated into the published national consensus standard because these requirements may be considered too restrictive or too specific for broader application by the nuclear industry. If these requirements are considered necessary for nuclear reactor program applications, the program standard will be revised and issued as a supplement to the national consensus standard. The supplemental program standard will contain only those necessary requirements not reflected by the national consensus standard. Therefore, while complete conversion of program standards may not always be realized, the standards policy has been fully supported in attempting to make maximum use of the national consensus standard. 1 tab

  11. Environmental radiation standards and risk limitation

    International Nuclear Information System (INIS)

    The Environmental Protection Agency and Nuclear Regulatory Commission have established environmental radiation standards for specific practices which correspond to limits on risk to the public that vary by several orders of magnitude and often are much less than radiation risks that are essentially unregulated, e.g., risks from radon in homes. This paper discusses a proposed framework for environmental radiation standards that would improve the correspondence with limitation of risk. This framework includes the use of limits on annual effective dose equivalent averaged over a lifetime, rather than limits on dose equivalent to whole body or any organ for each year of exposure, and consideration of exposures of younger age groups as well as adults; limits on annual effective dose equivalent averaged over a lifetime no lower than 0.25 mSv (25 mrem) per practice; maintenance of all exposures as low as reasonably achievable (ALARA); and establishment of a generally applicable de minimis dose for public exposures. Implications of the proposed regulatory framework for the current system of standards for limiting public exposures are discussed. 20 refs

  12. Adult attachment and psychosocial functioning

    OpenAIRE

    Pielage, Suzanne Brenda

    2006-01-01

    In the trilogy Attachment, Separation and Loss (1969, 1973, 1980), Bowlby theorized that early experiences with caregivers affect the quality of individuals’ later (romantic) relationships and, consequently, their mental health. The current thesis set out to examine the relationships between adult attachment and psychosocial functioning, predominately in the realm of close relationships. In the first part of the thesis, the focus lay on the assessment of the adult attachment construct. In Cha...

  13. Dosimetry standards

    International Nuclear Information System (INIS)

    The following leaflets are contained in this folder concerning the National Physical Laboratory's measurement services available in relation to dosimetry standards: Primary standards of X-ray exposure and X-ray irradiation facilities, X-ray dosimetry at therapy levels, Protection-level X-ray calibrations, Therapy-level gamma-ray facility, Fricke dosemeter reference service, Low-dose-rate gamma-ray facility, Penetrameter and kV meter calibration, Measurement services for radiation processing, Dichromate dosemeter reference service, Electron linear accelerator. (U.K.)

  14. Frequency standards

    CERN Document Server

    Riehle, Fritz

    2006-01-01

    Of all measurement units, frequency is the one that may be determined with the highest degree of accuracy. It equally allows precise measurements of other physical and technical quantities, whenever they can be measured in terms of frequency.This volume covers the central methods and techniques relevant for frequency standards developed in physics, electronics, quantum electronics, and statistics. After a review of the basic principles, the book looks at the realisation of commonly used components. It then continues with the description and characterisation of important frequency standards

  15. Research on Current Situation and Significance of MOOC Teaching Mode in Adult Colleges of Tianjin City%天津市成人高校实施慕课教学模式的现状及意义研究

    Institute of Scientific and Technical Information of China (English)

    崔广; 王晓楠; 房璐; 刘冬; 田东丽

    2016-01-01

    With the deep integration of “Internet+ education” ,it will be certainly necessary to make a reform in teaching mode of adult colleges .To implement MOOC teaching mode will solve the work-study conflicts of adult students better ,build up a convenient resources platform ,provide an ef‐fective learning way , promote the teachers to transform their teaching ideas , improve the education technology skills ,and accelerate the pace of teaching reform in adult colleges .%“互联网+教育”的深度融合,必然带来成人高校教学模式的改革,实施慕课教学模式,将能更好地解决成人学员的工学矛盾,搭建便利的资源平台,提供有效的学习途径,促进教师转变教学观念,提升能教育技术能力,加快成人高校教学改革的步伐。

  16. zebraflash transgenic lines for in vivo bioluminescence imaging of stem cells and regeneration in adult zebrafish

    OpenAIRE

    Chen, Chen-Hui; Durand, Ellen; Wang, Jinhu; Zon, Leonard I.; Poss, Kenneth D.

    2013-01-01

    The zebrafish has become a standard model system for stem cell and tissue regeneration research, based on powerful genetics, high tissue regenerative capacity and low maintenance costs. Yet, these studies can be challenged by current limitations of tissue visualization techniques in adult animals. Here we describe new imaging methodology and present several ubiquitous and tissue-specific luciferase-based transgenic lines, which we have termed zebraflash, that facilitate the assessment of rege...

  17. Signal Processing Strategies for Cochlear Implants Using Current Steering

    Directory of Open Access Journals (Sweden)

    Waldo Nogueira

    2009-01-01

    Full Text Available In contemporary cochlear implant systems, the audio signal is decomposed into different frequency bands, each assigned to one electrode. Thus, pitch perception is limited by the number of physical electrodes implanted into the cochlea and by the wide bandwidth assigned to each electrode. The Harmony HiResolution bionic ear (Advanced Bionics LLC, Valencia, CA, USA has the capability of creating virtual spectral channels through simultaneous delivery of current to pairs of adjacent electrodes. By steering the locus of stimulation to sites between the electrodes, additional pitch percepts can be generated. Two new sound processing strategies based on current steering have been designed, SpecRes and SineEx. In a chronic trial, speech intelligibility, pitch perception, and subjective appreciation of sound were compared between the two current steering strategies and standard HiRes strategy in 9 adult Harmony users. There was considerable variability in benefit, and the mean results show similar performance with all three strategies.

  18. [Adult twins].

    Science.gov (United States)

    Charlemaine, Christiane

    2006-12-31

    This paper explores the deep roots of closeness that twins share in their youngest age and their effect on their destiny at the adult age. Psychologists believe the bond between twins begins in utero and develops throughout the twins' lives. The four patterns of twinship described show that the twin bond is determined by the quality of parenting that twins receive in their infancy and early childhood. Common problems of adult twins bring about difficulties to adapt in a non-twin world. The nature versus nurture controversy has taken on new life focusing on inter-twin differences and the importance of parent-child interaction as fundamental to the growth and development of personality. PMID:17352324

  19. Alternative pharmacological strategies for adult ADHD treatment: a systematic review.

    Science.gov (United States)

    Buoli, Massimiliano; Serati, Marta; Cahn, Wiepke

    2016-01-01

    Adult Attention Deficit Hyperactivity Disorder (ADHD) is a prevalent psychiatric condition associated with high disability and frequent comorbidity. Current standard pharmacotherapy (methylphenidate and atomoxetine) improves ADHD symptoms in the short-term, but poor data were published about long-term treatment. In addition a number of patients present partial or no response to methylphenidate and atomoxetine. Research into the main database sources has been conducted to obtain an overview of alternative pharmacological approaches in adult ADHD patients. Among alternative compounds, amphetamines (mixed amphetamine salts and lisdexamfetamine) have the most robust evidence of efficacy, but they may be associated with serious side effects (e.g. psychotic symptoms or hypertension). Antidepressants, particularly those acting as noradrenaline or dopamine enhancers, have evidence of efficacy, but they should be avoided in patients with comorbid bipolar disorder. Finally metadoxine and lithium may be particularly suitable in case of comorbid alcohol misuse or bipolar disorder. PMID:26693882

  20. Adult Immunization

    OpenAIRE

    Omer Coskun

    2008-01-01

    Despite the many advances in modern medicine, each year thousands of people in the world die from diseases that are easily prevented by safe and effective vaccines. Few measures in preventive medicine are of such proven value and as easy to implement as routine immunization against infectious diseases. Prevention of infection by immunization is a lifelong process. There are a number of vaccines that all adults (¡I18 years) require. There are also other vaccines that need to be tailored t...

  1. Adult Leukemias

    OpenAIRE

    Moore, Lyall K.

    1984-01-01

    Over the past several years, advances have been made in the classification, diagnosis and therapy of the adult leukemias. The overall prognosis and quality of life have improved greatly, especially for patients with acute nonlymphoblastic leukemias. Some of the advances are described in this article. The importance of the clinical, laboratory and diagnostic tests for acute, chronic granulocytic and chronic lymphocytic leukemia are stressed. The therapy and prognosis for patients with the vari...

  2. Major Depression Among Adults

    Science.gov (United States)

    ... Children Autism Spectrum Disorder (ASD) Eating Disorders Among Adults - Anorexia Nervosa Eating Disorders Among Adults - Binge Eating Disorder Eating ... Children Autism Spectrum Disorder (ASD) Eating Disorders Among Adults - Anorexia Nervosa Eating Disorders Among Adults - Binge Eating Disorder Eating ...

  3. Panic Disorder among Adults

    Science.gov (United States)

    ... Children Autism Spectrum Disorder (ASD) Eating Disorders Among Adults - Anorexia Nervosa Eating Disorders Among Adults - Binge Eating Disorder Eating ... Children Autism Spectrum Disorder (ASD) Eating Disorders Among Adults - Anorexia Nervosa Eating Disorders Among Adults - Binge Eating Disorder Eating ...

  4. Bipolar Disorder Among Adults

    Science.gov (United States)

    ... Children Autism Spectrum Disorder (ASD) Eating Disorders Among Adults - Anorexia Nervosa Eating Disorders Among Adults - Binge Eating Disorder Eating ... Children Autism Spectrum Disorder (ASD) Eating Disorders Among Adults - Anorexia Nervosa Eating Disorders Among Adults - Binge Eating Disorder Eating ...

  5. Measuring sleep quality in older adults: a comparison using subjective and objective methods.

    Directory of Open Access Journals (Sweden)

    Glenn J Landry

    2015-09-01

    Full Text Available Sleep quality decreases with aging and thus sleep complaints are prevalent in older adults, particularly for those with cognitive impairment and dementia. For older adults, emerging evidence suggests poor sleep quality increases risk of developing cognitive impairment and dementia. Given the aging population – and the impending economic burden associated with increasing numbers of dementia patients – there is pressing need to improve sleep quality among older adults. As such, research efforts have increased focus on investigating the association between age-related sleep changes and cognitive decline in older adults. Sleep quality is a complex construct to evaluate empirically, and yet the Pittsburg Sleep Quality Index (PSQI is commonly used in studies as their only measure of sleep quality. Furthermore, the PSQI may not be the best sleep quality measure for older adults, due to its reliance on the cognitive capacity to reflect on the past month. Further study is needed to determine the PSQI’s validity among older adults. Thus, the current study examined sleep quality for 78 community dwelling adults 55+ to determine the PSQI’s predictive validity for objective sleep quality (as measured by actigraphy. We compared two subjective measures of sleep quality – the PSQI and Consensus Sleep Diary (CSD – with actigraphy (MotionWatch 8; camntech. Our results suggest perceived sleep quality is quite different from objective reality, at least for adults 55+. Importantly, we show this difference is unrelated to age, gender, education, or cognitive status (assessed using standard screens. Previous studies have shown the PSQI to be a valuable tool for assessing subjective sleep quality; however, our findings indicate for older adults the PSQI should not be used as a substitute for actigraphy, or vice versa. Hence, we conclude best practice is to include both subjective and objective measures when examining sleep quality in older adults (i.e., the

  6. Measuring sleep quality in older adults: a comparison using subjective and objective methods.

    Science.gov (United States)

    Landry, Glenn J; Best, John R; Liu-Ambrose, Teresa

    2015-01-01

    Sleep quality decreases with aging and thus sleep complaints are prevalent in older adults, particularly for those with cognitive impairment and dementia. For older adults, emerging evidence suggests poor sleep quality increases risk of developing cognitive impairment and dementia. Given the aging population-and the impending economic burden associated with increasing numbers of dementia patients-there is pressing need to improve sleep quality among older adults. As such, research efforts have increased focus on investigating the association between age-related sleep changes and cognitive decline in older adults. Sleep quality is a complex construct to evaluate empirically, and yet the Pittsburg Sleep Quality Index (PSQI) is commonly used in studies as their only measure of sleep quality. Furthermore, the PSQI may not be the best sleep quality measure for older adults, due to its reliance on the cognitive capacity to reflect on the past month. Further study is needed to determine the PSQI's validity among older adults. Thus, the current study examined sleep quality for 78 community dwelling adults 55+ to determine the PSQI's predictive validity for objective sleep quality (as measured by actigraphy). We compared two subjective measures of sleep quality-the PSQI and Consensus Sleep Diary (CSD)-with actigraphy (MotionWatch 8©; camntech). Our results suggest perceived sleep quality is quite different from objective reality, at least for adults 55+. Importantly, we show this difference is unrelated to age, gender, education, or cognitive status (assessed using standard screens). Previous studies have shown the PSQI to be a valuable tool for assessing subjective sleep quality; however, our findings indicate for older adults the PSQI should not be used as a substitute for actigraphy, or vice versa. Hence, we conclude best practice is to include both subjective and objective measures when examining sleep quality in older adults (i.e., the PSQI, CSD, and actigraphy). PMID

  7. 从体质测试标准的演变探讨现行标准的可行性%A discussion on the current standards’feasibility from the evolution of physical fitness test standards

    Institute of Scientific and Technical Information of China (English)

    阴欢; 陈棣

    2016-01-01

    对建国后不同时期的体育锻炼标准的出台背景、标准的测试项目及各标准及格成绩进行分析,论述标准的演变过程,揭示标准之间存在的内在联系,并从对比中找出《国家学生体质健康标准》(2014修订版)实施的可行性与不足之处,旨在为加强现代学校体育的教育工作及提高我国体质健康水平提供参考。%Through comparatively analyzed the background of establishment of physical fitness test standards in different era after the founding of new China, including test events and the evolution of pass standards, this article uncovers their inner link, and finds out the feasibility and shortages of the National Student Physical Health Standards(2014 Revision) from comparative study, in order to strengthen our modern school physical education teaching and develop our students’health level.

  8. A Review of the Current Situation and Development of the Standards of Foamed Concrete in China%我国泡沫混凝土标准化工作的现状与进展

    Institute of Scientific and Technical Information of China (English)

    郭向勇; 孙常青; 王建军

    2011-01-01

    作为新材料的泡沫混凝土由于具有轻质、节能利废、保温隔热、防火等性能,而且造价低廉,因此,正在我国各地逐步推广和应用.新材料的实施都是以标准为技术依据,我国泡沫混凝土标准目前处于起步阶段,正在逐步完善.该文介绍了泡沫混凝土的标准编制、发布与研究进展情况.%Foamed concrete is now gradually being put into application in China due to its merits of lightweight,energy conservation and waste utilization,thermal insulation,fire resistance,and cheap cost.The application of new materials must be based on standards,yet the standards for foamed concrete in China still need improving.The thesis makes a review of the compilation,issuing,and research progress of standards for foamed concrete in China.

  9. Validity of ultrasonography and measures of adult shoulder function and reliability of ultrasonography in detecting shoulder synovitis in patients with rheumatoid arthritis using magnetic resonance imaging as a gold standard.

    LENUS (Irish Health Repository)

    Bruyn, G A W

    2010-08-01

    To assess the intra- and interobserver reproducibility of musculoskeletal ultrasonography (US) in detecting inflammatory shoulder changes in patients with rheumatoid arthritis, and to determine the agreement between US and the Shoulder Pain and Disability Index (SPADI) and the Disabilities of the Arm, Shoulder, and Hand (DASH) questionnaire, using magnetic resonance imaging (MRI) as a gold standard.

  10. Generalized Quantum Current Algebras

    Institute of Scientific and Technical Information of China (English)

    ZHAO Liu

    2001-01-01

    Two general families of new quantum-deformed current algebras are proposed and identified both as infinite Hopf family of algebras, a structure which enables one to define "tensor products" of these algebras. The standard quantum affine algebras turn out to be a very special case of the two algebra families, in which case the infinite Hopf family structure degenerates into a standard Hopf algebra. The relationship between the two algebraic families as well as thefr various special examples are discussed, and the free boson representation is also considered.

  11. Standards development status. Summary report

    International Nuclear Information System (INIS)

    The Standards Development Status Summary Report is designed for scheduling, monitoring, and controlling the process by which Regulatory Standards, Guides, Reports, Petitions, and Environmental Statements are written. It is a summary of the current schedule plans for development of the above products

  12. Standard deviations

    CERN Document Server

    Smith, Gary

    2015-01-01

    Did you know that having a messy room will make you racist? Or that human beings possess the ability to postpone death until after important ceremonial occasions? Or that people live three to five years longer if they have positive initials, like ACE? All of these ‘facts' have been argued with a straight face by researchers and backed up with reams of data and convincing statistics.As Nobel Prize-winning economist Ronald Coase once cynically observed, ‘If you torture data long enough, it will confess.' Lying with statistics is a time-honoured con. In Standard Deviations, ec

  13. Adult hepatoblastoma

    OpenAIRE

    Javier A. Cienfuegos; Tania Labiano; Nicolás Pedano; Gabriel N. Zozaya; Pablo Martí-Cruchaga; Ángel Panizo; Fernando Rotellar

    2013-01-01

    Adult hepatoblastoma (AHB) is a very rare tumor, having been described 45 cases up to June 2012. In contrast to HB in infancy (IHB), it has poor prognosis. We present the case of a 37-year-old asymptomatic woman who consulted for a large -12 cm diameter- mass involving segments 5 and 6 of the liver, and alfa-fetoprotein of 1,556,30 UI/mL. A bisegmentectomy was carried out. The microscopic study confirmed the AHB diagnosis, revealing the presence of epithelial cells forming clusters, trabecula...

  14. Current Titles

    Energy Technology Data Exchange (ETDEWEB)

    Various

    2006-06-01

    This booklet is published for those interested in current research being conducted at the National Center for Electron Microscopy. The NCEM is a DOE-designated national user facility and is available at no charge to qualified researchers. Access is controlled by an external steering committee. Interested researchers may contact Jane Cavlina, Administrator, at 510/486-6036.

  15. Differing Perspectives on Older Adult Caregiving.

    Science.gov (United States)

    Brank, Eve M; Wylie, Lindsey E

    2016-07-01

    Informal older adult caregiving allows older adults to stay in their homes or live with loved ones, but decisions surrounding older adult care are fraught with complexities. Related research and case law suggest that an older adult's need for and refusal of help are important considerations; the current study is the first to examine these factors experimentally. Two samples (potential caregivers and care recipients) provided responses regarding anticipated emotions, caregiver abilities, and allocation of daily caregiving decision making based on a vignette portraying an older adult who had a high or low level of autonomy and who accepted or refused help. Study findings suggest differing views about caregiving; potential caregivers may not be as well prepared to take on caregiving as the potential care recipients anticipate and potential caregivers may allocate more decisional responsibility to older adults than the care recipients expect. Implications for older adult abuse are discussed. PMID:24652926

  16. 我国肉蛋制品质量安全标准现状与建议%Current situation and suggestions on quality and safety standard of meat and eggs products in China

    Institute of Scientific and Technical Information of China (English)

    周永昌; 黎华; 周志远

    2012-01-01

    The production and consumption of meat and years. But according to the requirement of food safety law problems about quality and safety standard of meat standard of meat and eggs products were analyzed in forward. eggs in China rank first in the world for 22 and the actual production conditions, some and eggs products still exist in China. Problem in this article and some reasonable suggestions were put%我国在肉蛋生产和消费方面已连续22年居世界第一,但根据《食品安全法》要求和生产实际情况,我国内蛋制品质量安全标准还存在一些问题亟待解决。文章分析了我国肉蛋制品标准存在的部分问题,并针对这些问题提出了一些合理的建议。

  17. Comparison of a standardized procedure with current laboratory practices for the detection of lupus anticoagulant in France. Working Group on Hemostasis of the Société Française de Biologie Clinique.

    Science.gov (United States)

    1993-11-15

    A multicenter study involving 13 laboratories was designed to compare a common procedure for screening lupus anticoagulants (LA) to the different practices currently in use in these laboratories. The common procedure combined 3 phospholipid-dependent assays, including mixing studies and a phospholipid neutralizing test. Due to the heterogeneity of LA expression, an abnormal result in at least one of the tests was sufficient to classify a sample as positive for LA. Consecutive samples referred for LA diagnosis were evaluated in parallel by each participant and the data found using the common procedure were analyzed independently according to mutually agreed cut-offs and criteria for sample classification. Within a period of 3 months, 535 samples were included, of which 147 were judged LA positive, 29 undetermined and 359 negative by the respective laboratories using their current practice. When using the common procedure, 149 plasmas were said to be positive, 38 undetermined and 348 negative. Absolute concordance occurred for 81% of the specimen population and absolute discordance (positive versus negative) for 7%. The level of agreement between the common procedure and the current practices, assessed by kappa indexes, indicated noticeable variations in the rates of detection from laboratory to laboratory. Among the different tests used in the common procedure, regular APTT was the least sensitive (about 50% detection) but none of the other tests alone recognized more than 73% of specimens from the LA positive population. This yield increased to about 90% with any combination of 2 sensitive tests.(ABSTRACT TRUNCATED AT 250 WORDS)

  18. Adult Sinusitis

    Science.gov (United States)

    ... a procedure performed in the physician’s office. No sedation or general anesthesia is needed for the procedure. ... diagnosing sinusitis. In current medical practice, a CT (CAT) scan is the study of choice for imaging ...

  19. International Standardization Activities for Optical Amplifiers

    Institute of Scientific and Technical Information of China (English)

    Haruo Okamura

    2003-01-01

    International standardization activities for Optical Amplifiers at IECTC86 and ITU-T SG15 are reviewed. Current discussions include Optical Amplifier safety guideline, Reliability standard, Rest methods of Noise and PMD, Definitions of Raman amplifier parameters and OA classification.

  20. Internet use, misuse, and addiction in adolescents: current issues and challenges.

    Science.gov (United States)

    Greydanus, Donald E; Greydanus, Megan M

    2012-01-01

    The Internet has revolutionized education and social communication in the 21st century. This article reviews the growing literature identifying a number of adolescents and young adults with a pathologically excessive Internet use leading to many potential consequences. Current research dilemmas in this area include that Internet addiction is a broad topic with no standard definition and no standard measurement tools. Management of youth with identified problematic Internet use or misuse centers on behavioral therapy and treatment of comorbidities. Pharmacologic approaches are limited at this time but are undergoing research, such as use of opioid antagonists and antidepressants in adults with pathological gambling. Efforts should be expanded on not only the education of all adolescents regarding the benefits but also the potential negative consequences of Internet use. It is vital that we do this for Generation Z, whereas Generation ALPHA will soon benefit or suffer from our efforts in this regard today.

  1. Survivorship care for older adults with cancer: U13 conference report.

    Science.gov (United States)

    Guerard, Emily J; Nightingale, Ginah; Bellizzi, Keith; Burhenn, Peggy; Rosko, Ashley; Artz, Andrew S; Korc-Grodzicki, Beatriz; Canin, Beverly; Dale, William; Ferrell, Betty

    2016-07-01

    Older adult cancer survivors currently account for almost 60% of all cancer survivors. The number of older cancer survivors will continue to increase as the population ages and as patients' live longer after a cancer diagnosis. As part of cancer center accreditation, the American College of Surgeons Commission on Cancer® (CoC) has placed great importance on survivorship care planning. While the CoC has set standards for general survivorship care, there is sparse evidence on how to best care for older adult cancer survivors. Concern exists among the medical community that survivorship care plans could increase paperwork without improving outcomes. Given the diverse and unique needs of older adult cancer survivors, the inter-professional team provides a structure and process for survivorship care built around the particular needs of older adults. The Cancer and Aging Research Group (CARG), in partnership with the NIA/NCI, held a U13 conference in May 2015 in part to discuss survivorship care for older adults with cancer. This report discusses four themes that emerged from one section of the conference: (1) survivorship care is a process that continually evolves to meet the needs of older adults; (2) older adult cancer survivors have unique needs and care plans should be tailored to meet these needs; (3) the inter-professional team is ideally suited to structure survivorship care of older adults; (4) patient advocacy must be encouraged throughout the cancer care continuum. As evidence based survivorship practices develop, the unique needs of older adults need to be given substantial attention.

  2. Supporting Wellness in Adult Online Education

    Science.gov (United States)

    Thompson, Jacklyn J.; Porto, Stella C. S.

    2014-01-01

    Online education cannot continue to grow at the current pace while ignoring a crucial component of campus support, wellness for adult online learners. This paper brings awareness to the concept of wellness as an important student support service in adult online education. It includes a summarized review of relevant literature and identifies…

  3. Marxism and Adult Education in Britain

    Science.gov (United States)

    Steele, Tom; Taylor, Richard

    2004-01-01

    In British adult education Marxism has been a persistent if marginalised current that has consistently informed its more radical movements and practitioners. This article firstly introduces some contested Marxist perspectives on adult education, particularly around the issues of ideology and incorporation into bourgeois society. Secondly, it…

  4. Adult attachment and psychosocial functioning

    NARCIS (Netherlands)

    Pielage, Suzanne Brenda

    2006-01-01

    In the trilogy Attachment, Separation and Loss (1969, 1973, 1980), Bowlby theorized that early experiences with caregivers affect the quality of individuals’ later (romantic) relationships and, consequently, their mental health. The current thesis set out to examine the relationships between adult a

  5. Mortality, AIDS-morbidity and loss to follow-up by current CD4 cell count among HIV-1 infected adults receiving antiretroviral therapy in Africa and Asia: data from the ANRS 12222 collaboration

    Science.gov (United States)

    Gabillard, Delphine; Lewden, Charlotte; Ndoye, Ibra; Moh, Raoul; Ségéral, Olivier; Tonwe-Gold, Besigin; Etard, Jean-François; Pagnaroat, Men; Fournier-Nicolle, Isabelle; Eholié, Serge; Konate, Issouf; Minga, Albert; Mpoudi-Ngolé, Eitel; Koulla-Shiro, Sinata; Zannou, Djimon Marcel; Anglaret, Xavier; Laurent, Christian

    2013-01-01

    Background In resource-limited countries, estimating CD4-specific incidence rates of mortality and morbidity among patients receiving antiretroviral therapy (ART) may help assess the effectiveness of care and treatment programmes, identify program weaknesses and inform decisions. Methods We pooled data from 13 research cohorts in five sub-Saharan African (Benin, Burkina Faso, Cameroon, Cote d'Ivoire and Senegal) and two Asian (Cambodia and Laos) countries. HIV-infected adults (≥18 years) who received ART in 1998-2008 and had at least one CD4 count available were eligible. Changes in CD4 counts over time were estimated by a linear mixed regression. CD4-specific incidence rates were estimated as the number of first events occurring in a given CD4 stratum divided by the time spent within the stratum. Results Overall 3,917 adults (62% women) on ART were followed-up during 10,154 person-years. In the ≤50, 51-100, 101-200, 201-350, 351-500, 501-650 and >650/mm3 CD4 cells strata, death rates were: 20.6, 11.8, 6.7, 3.3, 1.8, 0.9 and 0.3 per 100 person-years; AIDS rates were: 50.5, 32.9, 11.5, 4.8, 2.8, 2.2 and 2.2 per 100 person-years; and loss to follow-up rates were: 4.9, 6.1, 3.5, 3.1, 2.9, 1.7 and 1.2 per 100 person-years, respectively. Mortality and morbidity were higher during the first year following ART initiation. Conclusion In these resource-limited settings, death and AIDS rates remained substantial after ART initiation, even in individuals with high CD4 cell counts. Ensuring earlier ART initiation and optimizing case finding and treatment for AIDS-defining diseases should be seen as priorities. PMID:23274931

  6. 成年人重型血友病A预防及治疗现状与存在问题%Prophylaxis in adult patients with severe hemophilia A: prevention and treatment current status and problems

    Institute of Scientific and Technical Information of China (English)

    安利; 华宝来

    2015-01-01

    血友病A是一种由于凝血因子Ⅷ(FⅧ)基因缺陷,导致血浆FⅧ含量不足或功能缺陷,而引起X染色体连锁的隐性遗传性出血性疾病.重型血友病(SH)A(FⅧ∶C<1%)的特征性临床表现为自发性关节和肌肉反复出血,若不及时治疗可导致关节畸形,重者可致残,严重影响患者日常生活能力和生活质量.对于儿童SHA患者,预防治疗已成为世界血友病联盟(WFH)推荐的标准治疗方案;但对大多数成年人SHA患者而言,因已经存在关节损害,其能否从预防治疗中获益仍有争议.本文从疗效、个体化治疗、药物经济学、评价工具等方面,就成年人SHA患者预防治疗的现状和存在问题作一综述.%Hemophilia A is a hereditary,X-linked recessive bleeding disorder caused by deficiency or dysfunction of coagulation factor Ⅷ (FⅧ) in plasma.Patients with severe hemophilia A (SHA) have FⅧ activity<1% and are prone to frequent spontaneous bleeding particularly in joints and muscles.Recurrent joint bleeding can lead to chronic arthropathy,and then affect activities of daily living and quality of life of these patients.Prophylaxis,namely regular infusion of coagulation factor concentrate,has been demonstrated effectiveness in preventing hemarthrosis in children with SHA and is recommended as the management of choice by the World Federation of Hemophilia (WFH).However,its role in adults with SHA is still debated.In this review,authors focus on the benefits,cost,individualization and evaluation tools of the prophylaxis in adult patients with SHA.

  7. Adults' Views on Mathematics Education: A Midwest Sample

    Science.gov (United States)

    Brez, Caitlin C.; Allen, Jessica J.

    2016-01-01

    Currently, few studies have addressed public opinions regarding math education. The current study surveyed adults in a Midwestern town in the United States to assess opinions regarding math and math education. Overall, we found that adults believe that math is useful and that math education is important. We found that parents who currently have a…

  8. Adult Immunization

    Directory of Open Access Journals (Sweden)

    Omer Coskun

    2008-04-01

    Full Text Available Despite the many advances in modern medicine, each year thousands of people in the world die from diseases that are easily prevented by safe and effective vaccines. Few measures in preventive medicine are of such proven value and as easy to implement as routine immunization against infectious diseases. Prevention of infection by immunization is a lifelong process. There are a number of vaccines that all adults (¡I18 years require. There are also other vaccines that need to be tailored to meet individual variations in risk resulting from occupation, foreign travel, underlying illness, lifestyle and age. In this study, we tried to review this important subject. [TAF Prev Med Bull. 2008; 7(2: 159-166

  9. Adult Immunization

    Directory of Open Access Journals (Sweden)

    Omer Coskun

    2008-04-01

    Full Text Available Despite the many advances in modern medicine, each year thousands of people in the world die from diseases that are easily prevented by safe and effective vaccines. Few measures in preventive medicine are of such proven value and as easy to implement as routine immunization against infectious diseases. Prevention of infection by immunization is a lifelong process. There are a number of vaccines that all adults (¡I18 years require. There are also other vaccines that need to be tailored to meet individual variations in risk resulting from occupation, foreign travel, underlying illness, lifestyle and age. In this study, we tried to review this important subject. [TAF Prev Med Bull 2008; 7(2.000: 159-166

  10. Characteristics and Outcomes of Young Adult Opiate Users Receiving Residential Substance Abuse Treatment.

    Science.gov (United States)

    Morse, Siobhan; MacMaster, Samuel

    2015-01-01

    Opiate use patterns, user characteristics, and treatment response among young adults are of interest due to current high use prevalence and historical low levels of treatment engagement relative to older populations. Prior research in this population suggests that overall, young adults present at treatment with different issues. In this study the authors investigated potential differences between young adult (18-25 years of age) and older adult (26 and older) opiate users and the impact of differences relative to treatment motivation, length and outcomes. Data for this study was drawn from 760 individuals who entered voluntary, private, residential treatment. Study measures included the Addiction Severity Index (ASI), the Treatment Service Review (TSR), and University of Rhode Island Change Assessment (URICA). Interviews were conducted at program intake and 6-month post-discharge. Results indicate that older adults with a history of opiate use present at treatment with higher levels of severity for alcohol, medical, and psychological problems and young adults present at treatment with greater drug use and more legal issues. Significant improvement for both groups was noted at 6 months post treatment; there were also fewer differences between the two age groups of opiate users. Results suggest different strategies within treatment programs may provide benefit in targeting the disparate needs of younger opiate users. Overall, however, results suggest that individualized treatment within a standard, abstinence-based, residential treatment model can be effective across opiate users at different ages and with different issues, levels of severity, and impairment at intake. PMID:25879396

  11. Characteristics and Outcomes of Young Adult Opiate Users Receiving Residential Substance Abuse Treatment.

    Science.gov (United States)

    Morse, Siobhan; MacMaster, Samuel

    2015-01-01

    Opiate use patterns, user characteristics, and treatment response among young adults are of interest due to current high use prevalence and historical low levels of treatment engagement relative to older populations. Prior research in this population suggests that overall, young adults present at treatment with different issues. In this study the authors investigated potential differences between young adult (18-25 years of age) and older adult (26 and older) opiate users and the impact of differences relative to treatment motivation, length and outcomes. Data for this study was drawn from 760 individuals who entered voluntary, private, residential treatment. Study measures included the Addiction Severity Index (ASI), the Treatment Service Review (TSR), and University of Rhode Island Change Assessment (URICA). Interviews were conducted at program intake and 6-month post-discharge. Results indicate that older adults with a history of opiate use present at treatment with higher levels of severity for alcohol, medical, and psychological problems and young adults present at treatment with greater drug use and more legal issues. Significant improvement for both groups was noted at 6 months post treatment; there were also fewer differences between the two age groups of opiate users. Results suggest different strategies within treatment programs may provide benefit in targeting the disparate needs of younger opiate users. Overall, however, results suggest that individualized treatment within a standard, abstinence-based, residential treatment model can be effective across opiate users at different ages and with different issues, levels of severity, and impairment at intake.

  12. Current titles

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-07-01

    This booklet is published for those interested in current research being conducted at the National Center for Electron Microscopy. The NCEM is a DOE-designated national user facility and is available at no charge to qualified researchers. Access is controlled by an external steering committee. Interested researchers may contact Gretchen Hermes at (510) 486-5006 or address below for a User`s Guide. Copies of available papers can be ordered from: Theda Crawford National Center for Electron Microscopy, Lawrence Berkeley Laboratory, One Cyclotron Rd., MS72, Berkeley, California, USA 94720.

  13. Treatment of Acute Myeloid Leukemia in Adolescent and Young Adult Patients

    Directory of Open Access Journals (Sweden)

    Guldane Cengiz Seval

    2015-03-01

    Full Text Available The objectives of this review were to discuss standard and investigational treatment strategies for adolescent and young adult with acute myeloid leukemia, excluding acute promyelocytic leukemia. Acute myeloid leukemia (AML in adolescent and young adult patients (AYAs may need a different type of therapy than those currently used in children and older patients. As soon as AML is diagnosed, AYA patient should be offered to participate in well-designed clinical trials. The standard treatment approach for AYAs with AML is remission induction chemotherapy with an anthracycline/cytarabine combination, followed by either consolidation chemotherapy or stem cell transplantation, depending on the ability of the patient to tolerate intensive treatment and cytogenetic features. Presently, continuing progress of novel drugs targeting specific pathways in acute leukemia may bring AML treatment into a new era.

  14. Current ornithology

    CERN Document Server

    1983-01-01

    The appearance of the first volume of a projected series is the occasion for comment on scope, aims, and genesis of the work. The scope of Current Ornithology is all of the biology of birds. Ornithology, as a whole-organism science, is concerned with birds at every level of bi­ ological organization, from the molecular to the community, at least from the Jurassic to the present time, and over every scholarly discipline in which bird biology is done; to say this is merely to expand a dic­ tionary definition of "ornithology. " The aim of the work, to be realized over several volumes, is to present reviews or position statements con­ cerning the active fields of ornithological research. The reviews will be relatively short, and often will be done from the viewpoint of a readily­ identified group or school. Such a work could have come into being at any time within the past fifty years, but that Current Ornithology appears now is a result of events that are only seven to eight years old. One important event wa...

  15. Bone regeneration: current concepts and future directions

    Directory of Open Access Journals (Sweden)

    McGonagle Dennis

    2011-05-01

    Full Text Available Abstract Bone regeneration is a complex, well-orchestrated physiological process of bone formation, which can be seen during normal fracture healing, and is involved in continuous remodelling throughout adult life. However, there are complex clinical conditions in which bone regeneration is required in large quantity, such as for skeletal reconstruction of large bone defects created by trauma, infection, tumour resection and skeletal abnormalities, or cases in which the regenerative process is compromised, including avascular necrosis, atrophic non-unions and osteoporosis. Currently, there is a plethora of different strategies to augment the impaired or 'insufficient' bone-regeneration process, including the 'gold standard' autologous bone graft, free fibula vascularised graft, allograft implantation, and use of growth factors, osteoconductive scaffolds, osteoprogenitor cells and distraction osteogenesis. Improved 'local' strategies in terms of tissue engineering and gene therapy, or even 'systemic' enhancement of bone repair, are under intense investigation, in an effort to overcome the limitations of the current methods, to produce bone-graft substitutes with biomechanical properties that are as identical to normal bone as possible, to accelerate the overall regeneration process, or even to address systemic conditions, such as skeletal disorders and osteoporosis.

  16. Brain tumor - primary - adults

    Science.gov (United States)

    ... Vestibular schwannoma (acoustic neuroma) - adults; Meningioma - adults; Cancer - brain tumor (adults) ... Primary brain tumors include any tumor that starts in the brain. Primary brain tumors can start from brain cells, ...

  17. Adult Still's disease

    Science.gov (United States)

    Still's disease - adult; AOSD ... than 1 out of 100,000 people develop adult-onset Still's disease each year. It affects women more often than men. The cause of adult Still's disease is unknown. No risk factors for ...

  18. Neutral currents

    International Nuclear Information System (INIS)

    A short survey of the new experimental data on weak neutral currents is given, followed by a comparison with modern theoretical models. Cross sections of the anti νsub(e)e → anti νsub(e)e, anti νsub(μ)e→ νsub(μ)e, νp → νp and anti νp → anti νp elastic scattering as well as inclusive cross sections of the ν+N → ν+X and anti ν+N → anti ν+X deep inelastic scattering are presented. On the basis of the comparison the Weinberg-Salam model is concluded to be in a good agreement with the shape of the cross sections. Six-quark vector models appear to be ruled out. The five-quark model due to Achiman, Koller and Walsh and two versions of the Gursey-Sikivie model satisfactorily account for the observed data in shape and in magnitude

  19. Imaging of adult brainstem gliomas

    Energy Technology Data Exchange (ETDEWEB)

    Purohit, Bela, E-mail: purohitbela@yahoo.co.in; Kamli, Ali A.; Kollias, Spyros S.

    2015-04-15

    Highlights: •BSG are classified on MRI into diffuse low-grade, malignant, focal tectal and exophytic subtypes. •Their prognosis and treatment is variable and is almost similar to adult supratentorial gliomas. •This article illustrates the imaging of adult BSGs on MRI and FET-PET. •We also describe prognostic factors and the treatment options of these tumours. -- Abstract: Brainstem gliomas (BSGs) are uncommon in adults accounting for about 2% of all intracranial neoplasms. They are often phenotypically low-grade as compared to their more common paediatric counterparts. Since brainstem biopsies are rarely performed, these tumours are commonly classified according to their MR imaging characteristics into 4 subgroups: (a) diffuse intrinsic low-grade gliomas, (b) enhancing malignant gliomas, (c) focal tectal gliomas and (d) exophytic gliomas/other subtypes. The prognosis and treatment is variable for the different types and is almost similar to adult supratentorial gliomas. Radiotherapy (RT) with adjuvant chemotherapy is the standard treatment of diffuse low-grade and malignant BSGs, whereas, surgical resection is limited to the exophytic subtypes. Review of previous literature shows that the detailed imaging of adult BSGs has not received significant attention. This review illustrates in detail the imaging features of adult BSGs using conventional and advanced MR techniques like diffusion weighted imaging (DWI), diffusion tensor imaging (DTI), MR perfusion weighted imaging (PWI), MR spectroscopy (MRS), as well as {sup 18}F-fluoro-ethyl-tyrosine positron emission tomography ({sup 18}F-FET/PET). We have discussed the pertinent differences between childhood and adult BSGs, imaging mimics, prognostic factors and briefly reviewed the treatment options of these tumours.

  20. Using the Pragmatic Progressive Philosophy in Adult Education

    Science.gov (United States)

    Ellis, Marsha L.

    2012-01-01

    Using a pragmatic approach of progressive philosophy when educating adult learners utilizes the knowledge of history, to connect reality with current experiences through facilitated learning. The purpose of this paper is an attempt to show how adult education that uses a pragmatic progressive philosophy encompasses adult experiences,…

  1. Beyond Sex Education: How Adults Relate to Children's Sensuality.

    Science.gov (United States)

    Fogel, Alan

    Current cultural attitudes toward children's sexuality resemble attitudes toward adults' sexuality; there is an emphasis on purely genital and orgasmic pleasure. Adults and children need warmth, physical contact, and a sense of belonging for which genital stimulation may be unnecessary or inappropriate. Children's sexual advances to adults, as…

  2. The History of the Democratic Adult Education Movement in Spain

    Science.gov (United States)

    Oliver, Esther; Tellado, Itxaso; Yuste, Montserrat; Larena-Fernández, Rosa

    2016-01-01

    Background/Context: Traditional adult education in Spain treated the learner as a mere object that could be shaped by the educator. Although current practices of the democratic adult education movement in Spain reveals a completely opposite standpoint on adult education, there has been little analysis of the several influences converging and…

  3. Clopidogrel Resistance: Current Issues

    Directory of Open Access Journals (Sweden)

    NS Neki

    2016-05-01

    Full Text Available Antiplatelet agents are mainly used in the prevention and management of atherothrombotic complications. Dual antiplatelet therapy, combining aspirin and clopidogrel, is the standard care for patients having acute coronary syndromes or undergoing percutaneous coronary intervention according to the current ACC/AHA and ESC guidelines. But in spite of administration of dual antiplatelet therapy, some patients develop recurrent cardiovascular ischemic events especially stent thrombosis which is a serious clinical problem. Antiplatelet response to clopidogrel varies widely among patients based on ex vivo platelet function measurements. Clopidogrel is an effective inhibitor of platelet activation and aggregation due to its selective and irreversible blockade of the P2Y12 receptor. Patients who display little attenuation of platelet reactivity with clopidogrel therapy are labeled as low or nonresponders or clopidogrel resistant. The mechanism of clopidogrel resistance remains incompletely defined but there are certain clinical, cellular and genetic factors including polymorphisms responsible for therapeutic failure. Currently there is no standardized or widely accepted definition of clopidogrel resistance. The future may soon be realised in the routine measurement of platelet activity in the same way that blood pressure, cholesterol and blood sugar are followed to help guide the therapy, thus improving the care for millions of people. This review focuses on the methods used to identify patients with clopidogrel resistance, the underlying mechanisms, metabolism, clinical significance and current therapeutic strategies to overcome clopidogrel resistance. J Enam Med Col 2016; 6(1: 38-46

  4. The Vocational Turn in Adult Literacy Education and the Impact of the International Adult Literacy Survey

    Science.gov (United States)

    Druine, Nathalie; Wildemeersch, Danny

    2000-09-01

    The authors critically examine some of the underlying epistemological and theoretical assumptions of the IALS. In doing so, they distinguish among two basic orientations towards literacy. First, the standard approach (of which IALS is an example) subscribes to the possibility of measuring literacy as abstract, cognitive skills, and endorses the claim that there is an important relationship between literacy skills and economic success in the so-called 'knowledge society.' The second, called a socio-cultural approach, insists on the contextual and power-related character of people's literacy practices. The authors further illustrate that the assumptions of the IALS are rooted in a neo-liberal ideology that forces all members of society to adjust to the exigencies of the globalised economy. In the current, contingent conditions of the risk society, however, it does not seem very wise to limit the learning of adults to enhancing labour-market competencies. Adult education should relate to the concrete literacy practices people already have in their lives. It should make its learners co-responsible actors of their own learning process and participants in a democratic debate on defining the kind of society people want to build.

  5. 我国网络交易服务与管理标准化现状及改进探索研究%Research on the Current Situation and Improvement of the Standardization of Network Transaction Service and Management in China

    Institute of Scientific and Technical Information of China (English)

    周立军; 李秀娣; 杨静; 李南阳

    2016-01-01

    近年来,我国网络交易迅猛发展,并已成为全球网络销售第一大国。但与此同时,在网络交易过程中产业链各环节之间信息传递不畅、缺乏可信交易环境、产品质量低下等问题也日益突出,而标准化因其规范性、系统性和协调一致性而成为解决上述问题的重要支撑。本文在梳理标准化技术委员会、国家及行业标准制定、地方相关标准化工作现状的基础上,分析了网络交易服务与管理标准化存在的问题,并从建立标准体系、消除“标准孤岛”、提升标准质量等视角给出改进建议。%In recent years, network transactions have experienced rapid development in China, and China has become the world's largest network sales. But problems in every link of industry chain of network transaction process is becoming more and more prominent, such as information transmission is not smooth, lack of trusted trading environment and low product quality, etc. Standardization is an important support to solve the above problems because of its normative, systematic and coordinated consistency. Based on the current situation of standardization technical committee, national and industry standard development and revision, and local standardization work, this paper analyzes the existing problems of internet transaction services and management standardization, providing suggestions from the perspective of establishing the standards system, getting rid of “standard island”, improving the standard quality.

  6. Pediatric Patient Blood Management Programs: Not Just Transfusing Little Adults.

    Science.gov (United States)

    Goel, Ruchika; Cushing, Melissa M; Tobian, Aaron A R

    2016-10-01

    Red blood cell transfusions are a common life-saving intervention for neonates and children with anemia, but transfusion decisions, indications, and doses in neonates and children are different from those of adults. Patient blood management (PBM) programs are designed to assist clinicians with appropriately transfusing patients. Although PBM programs are well recognized and appreciated in the adult setting, they are quite far from standard of care in the pediatric patient population. Adult PBM standards cannot be uniformly applied to children, and there currently is significant variation in transfusion practices. Because transfusing unnecessarily can expose children to increased risk without benefit, it is important to design PBM programs to standardize transfusion decisions. This article assesses the key elements necessary for a successful pediatric PBM program, systematically explores various possible pediatric specific blood conservation strategies and the current available literature supporting them, and outlines the gaps in the evidence suggesting need for further/improved research. Pediatric PBM programs are critically important initiatives that not only involve a cooperative effort between pediatric surgery, anesthesia, perfusion, critical care, and transfusion medicine services but also need operational support from administration, clinical leadership, finance, and the hospital information technology personnel. These programs also expand the scope for high-quality collaborative research. A key component of pediatric PBM programs is monitoring pediatric blood utilization and assessing adherence to transfusion guidelines. Data suggest that restrictive transfusion strategies should be used for neonates and children similar to adults, but further research is needed to assess the best oxygenation requirements, hemoglobin threshold, and transfusion strategy for patients with active bleeding, hemodynamic instability, unstable cardiac disease, and cyanotic cardiac

  7. BAEA Becoming Adult Educators in the European Area

    DEFF Research Database (Denmark)

    Andersson, Per; Farinelli, Fiorella; Gross, Marin;

    , Estonia, Italy and Sweden) shows a strong political focus on labour market needs and relevance, when it comes to adult education provisions. This is paralleled by scarce attention paid to the role played by adult educators and their qualifications in supporting learning processes among the adult...... the conditions for current adult educators who are willing to progress in their careers, but experiencing difficulties in getting their competencies and qualification valued and rights fully recognised and protected at work....

  8. Performance in Older Adults

    Directory of Open Access Journals (Sweden)

    David Predovan

    2012-01-01

    Full Text Available Growing evidence supports the use of physical training interventions to improve both physical and cognitive performances in healthy older adults. Few studies have examined the impact of aerobic exercise on Stroop task performance, a measure of executive functions. In the current 3-month aerobic training study, 50 older adults (mean age = 67.96 ± 6.25 years were randomly assigned to either a three-month physical training group or to a control group (waiting list. Training sessions were 3 times per week for 60 minutes. All participants completed pre- and post-test measures of cognitive performance using the modified Stroop task and physical performance (Rockport one-mile test. Compared to controls, the training group showed significant improvements in physical capacity (P<0.001 and enhanced Stroop performance, but only in the inhibition/switching condition (P<0.03. Furthermore, the increase in aerobic capacity induced by the training regimen correlated negatively with reaction time in the inhibition/switching condition of the Stroop task at posttest (r=−0.538; P=0.007. Importantly, the reported gains in cognitive performance were observed after only three months of physical training. Taken together, the results suggest that even short-term physical interventions can enhance older adults’ executive functions.

  9. Darkness beyond the Standard Model

    International Nuclear Information System (INIS)

    With the discovery of the Higgs Boson all particles of the Standard Model of Particle Physics are experimentally identified. However, we know that the Standard Model can not explain all measurements. In particular several astrophysical measurements can not be explained within the Standard Model. A famous shortcoming is the existence of the so-called Dark Matter. A very well motivated candidate for the Dark Matter are WIMPs, weakly interactive massive particles. The current status of WIMP searches and the plans of the new experimental group at the Institute of High Energy Physics are presented. (author)

  10. National Green Building Standard Analysis

    Energy Technology Data Exchange (ETDEWEB)

    none,

    2012-07-01

    DOE's Building America Program is a research and development program to improve the energy performance of new and existing homes. The ultimate goal of the Building America Program is to achieve examples of cost-effective, energy efficient solutions for all U.S. climate zones. Periodic maintenance of an ANSI standard by review of the entire document and action to revise or reaffirm it on a schedule not to exceed five years is required by ANSI. In compliance, a consensus group has once again been formed and the National Green Building Standard is currently being reviewed to comply with the periodic maintenance requirement of an ANSI standard.

  11. Standard satellite data bus initiative

    Science.gov (United States)

    Spinney, Timothy; Yousef, Hassan

    The USAF Space Technology Center manages programs to reduce satellite costs through the appropriate use of microelectronics standardization. Ongoing programs such as the Standard Spacecraft Memory Module and Generic VHSIC Spaceborne Computer have provided an insight into the value of standardization and led to an initiative to coordinate microelectronics development around a standard satellite data bus, which should reduce costs by eliminating program- and contractor-unique interfaces, increasing production runs, and developing generic test equipment. Current efforts focus on the satellite housekeeping functions, and it is expected that the mission payload would also use this data bus. Based on existing housekeeping data-traffic requirements, several candidates have been identified for the standard data bus. The two candidates selected for further work are the ANSI X3T9.5 data bus and the linear token-passing data bus being proposed as part of the Advanced Tactical Fighter effort.

  12. Depression in Older Adults

    OpenAIRE

    Fiske, Amy; Wetherell, Julie Loebach; Gatz, Margaret

    2009-01-01

    Depression is less prevalent among older adults than among younger adults but can have serious consequences. Over half of cases represent a first onset in later life. Although suicide rates in the elderly are declining, they are still higher than in younger adults and more closely associated with depression. Depressed older adults are less likely to endorse affective symptoms and more likely to display cognitive changes, somatic symptoms, and loss of interest than are younger adults. Risk fac...

  13. A new method for discriminating transformer inrush current by combining the average standard deviation of 2-norm of the wave%结合波形后半波2-范数平均标准差鉴别变压器励磁涌流新方法

    Institute of Scientific and Technical Information of China (English)

    张凯; 董华英

    2013-01-01

    A new method for discriminating the inrush current by integrating the characteristics of the two kinds of current is presented based on large of simulation and testing.Because of the character that the magnetic inrush current leans to the one side of the time axis and the internal fault current is similar to the sine wave,the difference between the maximum and minimum and the unitary area in cycle is used as a general criterion to discriminate the unsymmetrical inrush current.For the symmetrical inrush current,we set a second criterion,which needs to calculate the average standard deviation of the 2-norm between the part data in the half cycle and the sine wave with the same length.validity of the new method is verified with simulating and testing.%在大量仿真和实验的基础上,综合变压器励磁涌流和内部故障电流的特点,提出了一种鉴别变压器励磁涌流的新方法.该方法基于励磁涌流偏于时间轴一侧和故障电流接近正弦波的特点,以周波内最值差别和归一化面积作为综合判据鉴别非对称的励磁涌流,而对于对称的励磁涌流,以后半周波内一部分数据与同窗长的标准正弦波的2-范数的平均标准差作为判据进行鉴别.仿真和实验验证了方法的正确性.

  14. European consensus statement on diagnosis and treatment of adult ADHD: the European Network adult ADHD

    LENUS (Irish Health Repository)

    Kooij, Sandra JJ

    2010-09-03

    Abstract Background Attention deficit hyperactivity disorder (ADHD) is among the most common psychiatric disorders of childhood that persists into adulthood in the majority of cases. The evidence on persistence poses several difficulties for adult psychiatry considering the lack of expertise for diagnostic assessment, limited treatment options and patient facilities across Europe. Methods The European Network Adult ADHD, founded in 2003, aims to increase awareness of this disorder and improve knowledge and patient care for adults with ADHD across Europe. This Consensus Statement is one of the actions taken by the European Network Adult ADHD in order to support the clinician with research evidence and clinical experience from 18 European countries in which ADHD in adults is recognised and treated. Results Besides information on the genetics and neurobiology of ADHD, three major questions are addressed in this statement: (1) What is the clinical picture of ADHD in adults? (2) How can ADHD in adults be properly diagnosed? (3) How should ADHD in adults be effectively treated? Conclusions ADHD often presents as an impairing lifelong condition in adults, yet it is currently underdiagnosed and treated in many European countries, leading to ineffective treatment and higher costs of illness. Expertise in diagnostic assessment and treatment of ADHD in adults must increase in psychiatry. Instruments for screening and diagnosis of ADHD in adults are available and appropriate treatments exist, although more research is needed in this age group.

  15. Implementing PAT with Standards

    Science.gov (United States)

    Chandramohan, Laakshmana Sabari; Doolla, Suryanarayana; Khaparde, S. A.

    2016-02-01

    Perform Achieve Trade (PAT) is a market-based incentive mechanism to promote energy efficiency. The purpose of this work is to address the challenges inherent to inconsistent representation of business processes, and interoperability issues in PAT like cap-and-trade mechanisms especially when scaled. Studies by various agencies have highlighted that as the mechanism evolves including more industrial sectors and industries in its ambit, implementation will become more challenging. This paper analyses the major needs of PAT (namely tracking, monitoring, auditing & verifying energy-saving reports, and providing technical support & guidance to stakeholders); and how the aforesaid reasons affect them. Though current technologies can handle these challenges to an extent, standardization activities for implementation have been scanty for PAT and this work attempts to evolve them. The inconsistent modification of business processes, rules, and procedures across stakeholders, and interoperability among heterogeneous systems are addressed. This paper proposes the adoption of specifically two standards into PAT, namely Business Process Model and Notation for maintaining consistency in business process modelling, and Common Information Model (IEC 61970, 61968, 62325 combined) for information exchange. Detailed architecture and organization of these adoptions are reported. The work can be used by PAT implementing agencies, stakeholders, and standardization bodies.

  16. Critical Review about Thematic Relations in Adults'Concepts

    Institute of Scientific and Technical Information of China (English)

    王莎瑷

    2016-01-01

    The general area investigated by Lin and Murphy was thematic relations used for classification in adults'category con-struction. The present study aims to discover whether thematic categorization could be found in American adult college students and whether thematic groupings have significant conceptual content. Most of the previous studies focus on children's classifica-tion, while the current study explores that of adults'. That is the significance of the current study.

  17. Supporting Academic Persistence in Low-Skilled Adult Learners

    Science.gov (United States)

    O'Neill, Susan; Thomson, Margareta Maria

    2013-01-01

    The current literature review explores the factors that contribute to academic persistence for adult learners. The aim of the study is to identify current research-based strategies aimed at supporting learner persistence, particularly for low-skilled adults. Elements of three theoretical frameworks, namely, expectancy-value theory (EVT), goal…

  18. Does the Current Account Still Matter?

    OpenAIRE

    Maurice Obstfeld

    2012-01-01

    Do global current account imbalances still matter in a world of deep international financial markets where gross two-way financial flows often dwarf the net flows measured in the current account? Contrary to a complete markets or 'consenting adults' view of the world, large current account imbalances, while very possibly warranted by fundamentals and welcome, can also signal elevated macroeconomic and financial stresses, as was arguably the case in the mid-2000s. Furthermore, the increasingly...

  19. CURRENT ACCOUNTING DEVELOPMENTS IN KOSOVO

    OpenAIRE

    NEXHMIE VOKSHI; MIHANE BERISHA-NAMANI

    2011-01-01

    For the study of the developments in accounting in Kosovo and its prospects, it is necessary to review the current situation of the developments in accounting, the recognition and acceptance of accounting standards. It is clear that the actual and perspective development level in an affected by many factors, such as social, cultural, etc. Therefore, the main aim of the research work in this study is to give an overview of the current developments of accounting in Kosovo. To obtain the require...

  20. TESOL Technology Standards: Description, Implementation, Integration

    Science.gov (United States)

    Teachers of English to Speakers of Other Languages, Inc. (TESOL), 2011

    2011-01-01

    The "TESOL Technology Standards" are applicable in a wide range of contexts: foreign language, second language, child, teen, adult, higher education, vocational education, language for specific purposes, and fully online programs; and in settings with low, medium, or high resources and access to communication technologies. Students, teachers,…

  1. Correctional Libraries, Library Standards, and Diversity.

    Science.gov (United States)

    Shirley, Glennor L.

    2003-01-01

    Respondents to a survey of prison librarians (n=35) regarding how they cope with demands for materials and services related to diversity issues felt that adherence to Library Standards for Adult Correctional Institutions was often impeded by security concerns. Racial differences between library providers and prisoners was not considered relevant.…

  2. The ANS mathematics and computation software standards

    Energy Technology Data Exchange (ETDEWEB)

    Smetana, A. O. [Savannah River National Laboratory, Washington Savannah River Company, Aiken, SC 29808 (United States)

    2006-07-01

    The Mathematics and Computations Div. of the American Nuclear Society sponsors the ANS-10 Standards Subcommittee. This subcommittee, which is part of the ANS Standards Committee, currently maintains three ANSI/ANS software standards. These standards are: Portability of Scientific and Engineering Software, ANS-10.2; Guidelines for the Verification and Validation of Scientific and Engineering Computer Programs for the Nuclear Industry, ANS-10.4; and Accommodating User Needs in Scientific and Engineering Computer Software Development, ANS-10.5. A fourth Standard, Documentation of Computer Software, ANS-10.3, is available as a historical Standard. (authors)

  3. Clues of subjective social status among young adults.

    Science.gov (United States)

    Nielsen, François; Roos, J Micah; Combs, R M

    2015-07-01

    We investigate determinants of subjective social status (SSS) as measured by respondents placing themselves on a ten-rung ladder from least to most "money", "education" and "respected job", in a large sample of young adults. The most potent clues of SSS are proximate in the life course, reflecting educational attainment and current socioeconomic and job situation, rather than distal characteristics such as family background, although relatively distal High school GPA has a lingering effect. Additional analyses reveal that College selectivity has a substantial impact on SSS, net of other variables in the model; Currently married does not significantly contribute to SSS, but contrary to some expectations Number of children significantly lowers SSS. We find no evidence of greater "status borrowing" by women as associations of SSS with shared household characteristics (Household income, Household assets, Home ownership) do not differ by gender. Our findings for these young adults support the conclusion of earlier research that SSS reflects a "cognitive averaging" of standard dimensions of socioeconomic status. PMID:26004468

  4. [Diagnostic workup and therapy of infectious diarrhea. Current standards].

    Science.gov (United States)

    Stallmach, A; Hagel, S; Lohse, A W

    2015-12-01

    Infectious diarrhea is very common; its severity ranges from uncomplicated, self-limiting courses to potentially life-threatening disease. A rapid diagnostic workup providing detailed information on the suspected pathogen should be performed only in patients at risk, analyzing one single stool sample for Salmonella, Shigella, Campylobacter, and Norovirus. In the presence of risk factors, such as a history of antibiotic exposure within the last 3 months, testing for Clostridium difficile should be performed. Immunocompetent patients do not require specific antibiotic therapy. Exceptions exist in patients with severe comorbidities, immunodeficiency, fever/SIRS, and in patients with Shigella or C. difficile infection. Empirical antibiotic treatment should be considered in patients with fever and/or bloody diarrhea and in patients at risk. In patients with traveler's diarrhea, microbiological diagnosis is required only in patients with fever, bloody diarrhea, prolonged course of disease (more than 5 days), severe clinical course with hypotension or dehydration, and during outbreaks. In these patients one single fecal sample should be collected for stool cultures of Campylobacter, Shigella, and Salmonella, as well as microscopic examination for amoebiasis and Giardiasis. The main therapeutic measure for infectious diarrhea is sufficient oral rehydration. As in community-acquired diarrhea, azithromycin or ciprofloxacin are recommended-taking into account local antimicrobial resistance in the country of travel and possible side effects. PMID:26573083

  5. Common Core Standards: The New U.S. Intended Curriculum

    Science.gov (United States)

    Porter, Andrew; McMaken, Jennifer; Hwang, Jun; Yang, Rui

    2011-01-01

    The Common Core standards released in 2010 for English language arts and mathematics have already been adopted by dozens of states. Just how much change do these new standards represent, and what is the nature of that change? In this article, the Common Core standards are compared with current state standards and assessments and with standards in…

  6. Perspectives on housing among homeless emerging adults.

    Science.gov (United States)

    Ryan, Tiffany N; Thompson, Sanna J

    2013-02-01

    Homeless emerging adults need the safety and stability of housing programs if they are to avoid the elements and victimization of the streets, however, barriers to obtaining housing are numerous. This study identified factors associated with perspectives of housing services among 29 homeless emerging adults (ages 18-23 years) through one-on-one interviews. Data were gathered and analyzed using grounded theory methodology for qualitative information. Major themes of peer support and positive personal and programmatic interactions in the context of emerging adult development were noted as important factors in housing service utilization. These major themes should be taken into consideration for current housing programs, due to homeless emerging adults' oscillation between their desire for formal support and personal independence. Greater emphasis on services that do not require long term commitments and are more flexible in addressing specific barriers to housing for homeless emerging adults may increase use.

  7. Current status in diabetic macular edema treatments

    Institute of Scientific and Technical Information of China (English)

    Pedro; Romero-Aroca

    2013-01-01

    Diabetes is a serious chronic condition,which increase the risk of cardiovascular diseases,kidney failure and nerve damage leading to amputation.Furthermore the ocular complications include diabetic macular edema,is the leading cause of blindness among adults in the industrialized countries.Today,blindness from diabetic macular edema is largely preventable with timely detection and appropriate interventional therapy.The treatment should include an optimized control of glycemia,arterial tension,lipids and renal status.The photocoagulation laser is currently restricted to focal macular edema in some countries,but due the high cost of intravitreal drugs,the use of laser treatment for focal and diffuse diabetic macular edema(DME),can be valid as gold standard in many countries.The intravitreal anti vascular endothelial growth factor drugs(ranibizumab and bevacizumab),are indicated in the treatment of all types of DME,but the correct protocol for administration should be defined for the different Retina Scientific Societies.The corticosteroids for diffuse DME,has a place in pseudophakic patients,but its complications restricted the use of these drugs for some patients.Finally the intravitreal interface plays an important role and its exploration is mandatory in all DME patients.

  8. Quality and standards in electronics

    CERN Document Server

    Tricker, Ray

    1997-01-01

    A manufacturer or supplier of electronic equipment or components needs to know the precise requirements for component certification and quality conformance to meet the demands of the customer. This book ensures that the professional is aware of all the UK, European and International necessities, knows the current status of these regulations and standards, and where to obtain them.

  9. Standardized Testing and School Accountability

    Science.gov (United States)

    Wiliam, Dylan

    2010-01-01

    This article explores the use of standardized tests to hold schools accountable. The history of testing for accountability is reviewed, and it is shown that currently between-school differences account for less than 10% of the variance in student scores, in part because the progress of individuals is small compared to the spread of achievement…

  10. Standardization in optical coating characterisation

    Institute of Scientific and Technical Information of China (English)

    D.Ristau

    2005-01-01

    In the rapid development course of laser technology and modern optics, optical metrology continuously gains importance for the quality management in the industrial production environment and also for research in optical coatings. Besides absorption and scatter losses, the spectral characteristics and laser induced damage thresholds are considered as common quality factors for coated optical components and often define the optimization targets for new products and applications. Also, these quality parameters are the basis for the comparison of commercial optics and can be found in the product catalogues of most manufacturers of optical components. As a consequence, standardization of characterisation procedures for these fundamental properties evolved to a crucial point for the optics industry. During the last decade, adapted standard measurement techniques have been elaborated and discussed by representatives from many industrial companies and research institutes within working groups of the International Organisation for Standardization (ISO). In this contribution, the current state of standardized characterisation techniques for optical coatings is summarised. Selected standards for the measurement of absorption (ISO 11551), scattering (ISO 13696) and laser induced damage thresholds (ISO 11254, Parts 1 and 2) will be described and discussed in view of their applicability and reproducibility. The report will be concluded by an outlook on the current projects and future tasks of standardization in optics characterisation.

  11. The Current in a Wire

    Science.gov (United States)

    Thompson, Keith

    2009-01-01

    This little problem arose because I was frustrated with the standard electromagnetism texts, which show the magnetic field due to a current-bearing wire outside the wire [proportional to] 1/r and inside [proportional to] r. However, they never point out that the moving electrons must be influenced by the magnetic field created by the other moving…

  12. Communicating with young adults with cystic fibrosis.

    OpenAIRE

    Webb, A. K.

    1995-01-01

    The care of the young adult with cystic fibrosis is complex, requiring a multidisciplinary input from different carers. Communication with and education of patients covers many areas; topics may include medical and personal problems, transplantation, survival, current scientific breakthroughs and the future. Communicating in these areas with knowledgeable young adults requires skill, tact and self-education upon the part of the cystic fibrosis team.

  13. Application Guideline for Vitamin D and Bone Health in Adult Chinese(2014 Standard Edition) Vitamin D Working Group of Osteoporosis Committee of China Gerontological Society%维生素D与成年人骨骼健康应用指南(2014年标准版)

    Institute of Scientific and Technical Information of China (English)

    廖祥鹏; 张增利; 张红红; 朱汉民; 周建烈; 黄琪仁; 汪之顼; 王亮; 刘忠厚

    2014-01-01

    Vitamin D may contribute to widespread effects in human health, and vitamin D deficiency may lead to the development of osteoporosis, and to falls and fractures;meanwhile, there have been some conflicting guidelines and inconsistent practices about vitamin D in the West.Given these conditions, some specialists from Osteoporosis Committee of China Gerontological Society develop this practical application guideline for vitamin D and bone health in adult Chinese.This guideline includes“Starter Edition”and“Standard Edition”, and the evidence of this guideline mainly comes from the guideline of National Osteoporosis Society in the UK (2013), the report of Institute of Medicine in the United States (2011), supported by some domestic literatures.This guideline addresses the management of vitamin D deficiency in adult patients with, or at risk of developing, bone disease.It should be noted that the management of vitamin D deficiency in childhood, in pregnancy or in patients with severe or end-stage chronic kidney disease (CKD Stages 4-5) is beyond the topic of this guideline.Based on the published"Starter Edition"in this journal, this"Standard Edition"goes further;and the contents of this guideline includes the setting up of vitamin D thresholds for adult Chinese, assessment of vitamin D status, interpretation of 25OHD measurement, detailed plan of vitamin D treatment and monitoring, and prevention strategy for vitamin D deficiency.%维生素D对人体健康产生广泛作用,维生素D缺乏症( Vitamin D deficiency)可能会导致骨质疏松症进展、跌倒和骨折;同时,在西方国家出现了不一致维生素D标准和实践方案。鉴于此,中国老年学会骨质疏松委员会相关专业人员,制定了《维生素D与成年人骨骼健康应用指南》。该《指南》分为《简化版》和《标准版》,主要证据来源于2013年英国骨质疏松学会指南、2011年美国健康研究院报告,以及国内文献。该

  14. GH Replacement Therapy in GH-Deficient Adults

    OpenAIRE

    Luger A

    2006-01-01

    Growth hormone (GH) deficiency represents an indication for substitution therapy not only in children but also in adults. In the last twenty years, numerous studies have shown that GH deficiency in adults is characterized by a clearly defined syndrome which is associated with a doubleincreased mortality rate. GH deficiency in adults can be diagnosed only by dynamic tests. While the insulin tolerance test (ITT) has been the standard test in the past, the combined arginine-GH releasing hormon...

  15. Status of conversion of DOE standards to non-Government standards

    Energy Technology Data Exchange (ETDEWEB)

    Moseley, H.L.

    1992-07-01

    One major goal of the DOE Technical Standards Program is to convert existing DOE standards into non-Government standards (NGS's) where possible. This means that a DOE standard may form the basis for a standards-writing committee to produce a standard in the same subject area using the non-Government standards consensus process. This report is a summary of the activities that have evolved to effect conversion of DOE standards to NGSs, and the status of current conversion activities. In some cases, all requirements in a DOE standard will not be incorporated into the published non-Government standard because these requirements may be considered too restrictive or too specific for broader application by private industry. If requirements in a DOE standard are not incorporated in a non-Government standard and the requirements are considered necessary for DOE program applications, the DOE standard will be revised and issued as a supplement to the non-Government standard. The DOE standard will contain only those necessary requirements not reflected by the non-Government standard. Therefore, while complete conversion of DOE standards may not always be realized, the Department's technical standards policy as stated in Order 1300.2A has been fully supported in attempting to make maximum use of the non-Government standard.

  16. Status of conversion of DOE standards to non-Government standards

    Energy Technology Data Exchange (ETDEWEB)

    Moseley, H.L.

    1992-07-01

    One major goal of the DOE Technical Standards Program is to convert existing DOE standards into non-Government standards (NGS`s) where possible. This means that a DOE standard may form the basis for a standards-writing committee to produce a standard in the same subject area using the non-Government standards consensus process. This report is a summary of the activities that have evolved to effect conversion of DOE standards to NGSs, and the status of current conversion activities. In some cases, all requirements in a DOE standard will not be incorporated into the published non-Government standard because these requirements may be considered too restrictive or too specific for broader application by private industry. If requirements in a DOE standard are not incorporated in a non-Government standard and the requirements are considered necessary for DOE program applications, the DOE standard will be revised and issued as a supplement to the non-Government standard. The DOE standard will contain only those necessary requirements not reflected by the non-Government standard. Therefore, while complete conversion of DOE standards may not always be realized, the Department`s technical standards policy as stated in Order 1300.2A has been fully supported in attempting to make maximum use of the non-Government standard.

  17. Older Adults and Depression

    Science.gov (United States)

    ... Older Adults and Depression Share Older Adults and Depression Download PDF Download ePub Download Mobi Order a ... If so, you may have depression. What is depression? Everyone feels down or sad sometimes, but these ...

  18. Bathroom safety - adults

    Science.gov (United States)

    ... this page: //medlineplus.gov/ency/patientinstructions/000021.htm Bathroom safety - adults To use the sharing features on this page, please enable JavaScript. Older adult bathroom safety What to consider at home Staying safe ...

  19. Marriage Matters But How Much? Marital Centrality Among Young Adults.

    Science.gov (United States)

    Willoughby, Brian J; Hall, Scott S; Goff, Saige

    2015-01-01

    Marriage, once a gateway to adulthood, is no longer as widely considered a requirement for achieving adult status. With declining marriage rates and delayed marital transitions, some have wondered whether current young adults have rejected the traditional notion of marriage. Utilizing a sample of 571 young adults, the present study explored how marital centrality (the expected importance to be placed on the marital role relative to other adult roles) functioned as a unique and previously unexplored marital belief among young adults. Results suggested that marriage remains an important role for many young adults. On average, young adults expected that marriage would be more important to their life than parenting, careers, or leisure activities. Marital centrality profiles were found to significantly differ based on both gender and religiosity. Marital centrality was also associated with various outcomes including binge-drinking and sexual activity. Specifically, the more central marriage was expected to be, the less young adults engaged in risk-taking or sexual behaviors.

  20. Guidelines and Quality Standards for Adults with Epilepsy.

    Science.gov (United States)

    Pugh, Mary Jo; McMillan, Katharine K

    2016-05-01

    Guidelines and quality measures for epilepsy care have the potential to improve the quality of epilepsy care. Quality measures are increasingly used for pay-for-performance. This article describes different guidelines and quality measures that have been used to identify best practices, types of best practices for use in clinical care developed using each of these approaches, and information on how to interpret the recommendations in specific guidelines and quality measures described elsewhere in this issue. PMID:27086980

  1. Executive Function Impairments in High IQ Adults with ADHD

    Science.gov (United States)

    Brown, Thomas E.; Reichel, Philipp C.; Quinlan, Donald M.

    2009-01-01

    Objectives: To demonstrate that high IQ adults diagnosed with ADHD suffer from executive function (EF) impairments that: a) can be identified with a combination of standardized measures and self-report data; and b) occur more commonly in this group than in the general population. Method: 157 ADHD adults with IQ greater than or equal to 120 were…

  2. Development of False Memories in Bilingual Children and Adults

    Science.gov (United States)

    Howe, Mark L.; Gagnon, Nadine; Thouas, Lisa

    2008-01-01

    The effects of within- versus between-languages (English-French) study and test on rates of bilingual children's and adults' true and false memories were examined. Children aged 6 through 12 and university-aged adults participated in a standard Deese-Roediger-McDermott false memory task using free recall and recognition. Recall results showed…

  3. Dividing Attention Lowers Children's but Increases Adults' False Memories

    Science.gov (United States)

    Otgaar, Henry; Peters, Maarten; Howe, Mark L.

    2012-01-01

    The present study examined the impact of divided attention on children's and adults' neutral and negative true and false memories in a standard Deese/Roediger-McDermott paradigm. Children (7- and 11-year-olds; n = 126) and adults (n = 52) received 5 neutral and 5 negative Deese/Roediger-McDermott word lists; half of each group also received a…

  4. Quality Assurance Model for Digital Adult Education Materials

    Science.gov (United States)

    Dimou, Helen; Kameas, Achilles

    2016-01-01

    Purpose: This paper aims to present a model for the quality assurance of digital educational material that is appropriate for adult education. The proposed model adopts the software quality standard ISO/IEC 9126 and takes into account adult learning theories, Bloom's taxonomy of learning objectives and two instructional design models: Kolb's model…

  5. The Place of Indian Culture in Adult Education

    Science.gov (United States)

    Regan, Timothy F.; Pagane, Jules

    1971-01-01

    Standard readers in their concept violate Navajo taboos and thus create conflicts for the adult student. By changing the practice of using irrelevant materials, adult education could act as a dramatic change agent by convincing the Indian to view education and school as something important and challenging to him. (Author/MS)

  6. Understanding Innovation: Youth-Adult Partnerships in Decision Making

    Science.gov (United States)

    Zeldin, Shepherd; Petrokubi, Julie

    2006-01-01

    In the United States, the concept of youth-adult partnership remains innovative. The notion that youth and adults can collaborate on issues of importance runs counter to prevailing societal norms, public policies, structures and standards of practice. There is not much cultural or policy support for managers seeking to integrate youth-adult…

  7. Current Approaches in the Treatment of Relapsed and Refractory Acute Myeloid Leukemia

    Directory of Open Access Journals (Sweden)

    Nestor R. Ramos

    2015-04-01

    Full Text Available The limited sensitivity of the historical treatment response criteria for acute myeloid leukemia (AML has resulted in a different paradigm for treatment compared with most other cancers presenting with widely disseminated disease. Initial cytotoxic induction chemotherapy is often able to reduce tumor burden to a level sufficient to meet the current criteria for “complete” remission. Nevertheless, most AML patients ultimately die from their disease, most commonly as clinically evident relapsed AML. Despite a variety of available salvage therapy options, prognosis in patients with relapsed or refractory AML is generally poor. In this review, we outline the commonly utilized salvage cytotoxic therapy interventions and then highlight novel investigational efforts currently in clinical trials using both pathway-targeted agents and immunotherapy based approaches. We conclude that there is no current standard of care for adult relapsed or refractory AML other than offering referral to an appropriate clinical trial.

  8. Challenging Perspectives on Young Adult Literature

    Science.gov (United States)

    Conners, Sean P.

    2013-01-01

    As proponents of the Common Core State Standards (CCSS) publish lists of "Exemplar Texts" that are said to represent the degree of textual complexity appropriate for the different grade levels, and that are overwhelmingly canonical, those who value young adult literature and recognize a place for it in the high school literature…

  9. Can bivalve veligers escape feeding currents of adult bivalves?

    NARCIS (Netherlands)

    Troost, K.; Veldhuizen, R.; Stamhuis, E.J.; Wolff, W.

    2008-01-01

    While the stock of introduced Pacific oysters (Crassostrea gigas) increased in the Oosterschelde estuary (SW Netherlands), so did the filtration pressure of all bivalve species together. In the same period, stocks of native bivalves declined slightly. The expansion of Pacific oysters in Dutch estuar

  10. Hepatoblastoma of the adult: A systematic review of the literature.

    Science.gov (United States)

    Celotti, Andrea; D'Amico, Giuseppe; Ceresoli, Marco; Tomasoni, Matteo; Raimondo, Stefano; Baggi, Paolo; Baiocchi, Gian Luca

    2016-09-01

    Hepatoblastoma is the most common malignant liver tumor in children. On the other hand in the adult HB is very rare and characterized by unfavorable prognosis. A review of the entire literature was performed: 58 articles and 63 cases of HB were found. The patient's data were collected and analyzed. No correlation with hepatitis virus was found and AFP was elevated in most cases. Usually HB forms a large single mass in the liver and presents aggressive behavior, with local invasiveness and metastatic spread. The current median survival time is 5 months, with a 1-year survival rate near 30%. Surgical resection is the only curative treatment. However major liver resections or extensive demolitions of the adjacent organs are necessary. There are no standardized protocols in the multimodal approach to this tumor. PMID:27566042

  11. Humidification during mechanical ventilation in the adult patient.

    Science.gov (United States)

    Al Ashry, Haitham S; Modrykamien, Ariel M

    2014-01-01

    Humidification of inhaled gases has been standard of care in mechanical ventilation for a long period of time. More than a century ago, a variety of reports described important airway damage by applying dry gases during artificial ventilation. Consequently, respiratory care providers have been utilizing external humidifiers to compensate for the lack of natural humidification mechanisms when the upper airway is bypassed. Particularly, active and passive humidification devices have rapidly evolved. Sophisticated systems composed of reservoirs, wires, heating devices, and other elements have become part of our usual armamentarium in the intensive care unit. Therefore, basic knowledge of the mechanisms of action of each of these devices, as well as their advantages and disadvantages, becomes a necessity for the respiratory care and intensive care practitioner. In this paper, we review current methods of airway humidification during invasive mechanical ventilation of adult patients. We describe a variety of devices and describe the eventual applications according to specific clinical conditions.

  12. Humidification during Mechanical Ventilation in the Adult Patient

    Directory of Open Access Journals (Sweden)

    Haitham S. Al Ashry

    2014-01-01

    Full Text Available Humidification of inhaled gases has been standard of care in mechanical ventilation for a long period of time. More than a century ago, a variety of reports described important airway damage by applying dry gases during artificial ventilation. Consequently, respiratory care providers have been utilizing external humidifiers to compensate for the lack of natural humidification mechanisms when the upper airway is bypassed. Particularly, active and passive humidification devices have rapidly evolved. Sophisticated systems composed of reservoirs, wires, heating devices, and other elements have become part of our usual armamentarium in the intensive care unit. Therefore, basic knowledge of the mechanisms of action of each of these devices, as well as their advantages and disadvantages, becomes a necessity for the respiratory care and intensive care practitioner. In this paper, we review current methods of airway humidification during invasive mechanical ventilation of adult patients. We describe a variety of devices and describe the eventual applications according to specific clinical conditions.

  13. APS beamline standard components handbook

    International Nuclear Information System (INIS)

    It is clear that most Advanced Photon Source (APS) Collaborative Access Team (CAT) members would like to concentrate on designing specialized equipment related to their scientific programs rather than on routine or standard beamline components. Thus, an effort is in progress at the APS to identify standard and modular components of APS beamlines. Identifying standard components is a nontrivial task because these components should support diverse beamline objectives. To assist with this effort, the APS has obtained advice and help from a Beamline Standardization and Modularization Committee consisting of experts in beamline design, construction, and operation. The staff of the Experimental Facilities Division identified various components thought to be standard items for beamlines, regardless of the specific scientific objective of a particular beamline. A generic beamline layout formed the basis for this identification. This layout is based on a double-crystal monochromator as the first optical element, with the possibility of other elements to follow. Pre-engineering designs were then made of the identified standard components. The Beamline Standardization and Modularization Committee has reviewed these designs and provided very useful input regarding the specifications of these components. We realize that there will be other configurations that may require special or modified components. This Handbook in its current version (1.1) contains descriptions, specifications, and pre-engineering design drawings of these standard components. In the future, the APS plans to add engineering drawings of identified standard beamline components. Use of standard components should result in major cost reductions for CATs in the areas of beamline design and construction

  14. Standard environmental test methods

    Energy Technology Data Exchange (ETDEWEB)

    Schafer, D R

    1983-12-01

    This guide to uniformity in testing is intended primarily as an aid to persons responsible for designing, developing, and performing environmental tests. It will also be of use to those concerned with production, evaluation, and quality control and assurance. Checklists for preparing the environmental testing portion of product specifications are included, as are copies of Process Standards covering the instrumentation, equipment, and methods for use in environmental testing of Sandia National Laboratories components. Techniques and equipment are constantly improving. This version of SC-4452 reflects current state-of-the-art and practice in environmental testing. Previously existing sections of the document have ben updated and new ones have been added, e.g., Transient Testing on Vibration Machines.

  15. The Adult Experience.

    Science.gov (United States)

    Belsky, Janet

    The 14 chapters of this textbook chronicle adult development from youth through old age, emphasizing both research and interviews with adults at various stages in their lives. Topics covered include the following: (1) the academic field of adult development; (2) theories and research methods; (3) aging and disease prevention; (4) sexuality and…

  16. Dimensions of Adult Learning

    Science.gov (United States)

    Foley, Griff, Ed.

    2004-01-01

    This broad introduction to adult and postcompulsory education offers an overview of the field for students, adult educators and workplace trainers. The book establishes an analytical framework to emphasize the nature of learning and agency of learners; examines the core knowledge and skills that adult educators need; discusses policy, research and…

  17. Sexuality in Older Adults

    Science.gov (United States)

    MENU Return to Web version Sexuality in Older Adults Sexuality in Older Adults What are the benefits of a healthy sex life for older adults? Sex is ... concerns, and acknowledge new relationships with respect. Bibliography Sexuality in Later Life by National Institute on Aging ( ...

  18. Adult Survival Skills Assessment.

    Science.gov (United States)

    Walsko, Gregory M.

    The purpose of this instrument is to supplement data from the Adult Basic Learning Examination in assessing the functional level of adults in daily situations. It may also be used as a teaching tool for adults requesting tutoring in specific concepts and skills presented in the instrument. This instrument is an informal assessment instrument and…

  19. Adults Learning for Development.

    Science.gov (United States)

    Rogers, Alan

    This book, drawing on 30 years of adult education experience in England, Ireland, India, and other countries, contrasts the individualistic approach to adult education in the West with the social responsibility view of adult education in the developing world. The book's thesis is that the gulf between the approach of the West and that of…

  20. Adult Education in Turkey

    Science.gov (United States)

    Miser, Rifat; Ural, Ozana; Ünlühisarýklý, Özlem

    2013-01-01

    This study investigates the situation and practices of adult education in Turkey in terms of (a) participants, (b) providers, and (c) program areas. The data were derived from published statistical data and one-to-one interaction with adult education providers when such data are unavailable. Turkey has a long tradition of adult education with…

  1. Adults Role in Bullying

    Science.gov (United States)

    Notar, Charles E.; Padgett, Sharon

    2013-01-01

    Do adults play a role in bullying? Do parents, teachers, school staff, and community adult leaders influence bullying behavior in children and teenagers? This article will focus on research regarding all adults who have almost daily contact with children and teens and their part in how bullying is identified, addressed, and prevented. This article…

  2. Qualification paths of adult educators in Sweden and Denmark

    DEFF Research Database (Denmark)

    Andersson, Per; Köpsén, Susanne; Larson, Anne;

    2013-01-01

    are often long and winding roads. Becoming an adult educator could be their primary desire, but it could also be their ‘Plan B’, a second choice. Individual motives and external demands interact in the professionalisation process. A shift in focus from teaching subject and methods to teaching context......The qualification of adult educators is a central aspect of the quality of adult education. However, within current policy discourses and adult education research on the professional development of prospective adult educators, little attention is paid to teacher qualification when compared to other...

  3. State Standards and State Assessment Systems: A Guide to Alignment. Series on Standards and Assessments.

    Science.gov (United States)

    La Marca, Paul M.; Redfield, Doris; Winter, Phoebe C.

    Alignment of content standards, performance standards, and assessments is crucial. This guide contains information to assist states and districts in aligning their assessment systems to their content and performance standards. It includes a review of current literature, both published and fugitive. The research is woven together with a few basic…

  4. Adult height, nutrition, and population health.

    Science.gov (United States)

    Perkins, Jessica M; Subramanian, S V; Davey Smith, George; Özaltin, Emre

    2016-03-01

    In this review, the potential causes and consequences of adult height, a measure of cumulative net nutrition, in modern populations are summarized. The mechanisms linking adult height and health are examined, with a focus on the role of potential confounders. Evidence across studies indicates that short adult height (reflecting growth retardation) in low- and middle-income countries is driven by environmental conditions, especially net nutrition during early years. Some of the associations of height with health and social outcomes potentially reflect the association between these environmental factors and such outcomes. These conditions are manifested in the substantial differences in adult height that exist between and within countries and over time. This review suggests that adult height is a useful marker of variation in cumulative net nutrition, biological deprivation, and standard of living between and within populations and should be routinely measured. Linkages between adult height and health, within and across generations, suggest that adult height may be a potential tool for monitoring health conditions and that programs focused on offspring outcomes may consider maternal height as a potentially important influence.

  5. Standards help enterprises

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    @@ Standardization in modern times began from the Industrial Revolution. Various industrial sectors, for which about 300 standardization technical commissions have been established, make up the key fields of China's standardization.

  6. Obsessive Compulsive Disorder among Adults

    Science.gov (United States)

    ... Children Autism Spectrum Disorder (ASD) Eating Disorders Among Adults - Anorexia Nervosa Eating Disorders Among Adults - Binge Eating Disorder Eating ... Children Autism Spectrum Disorder (ASD) Eating Disorders Among Adults - Anorexia Nervosa Eating Disorders Among Adults - Binge Eating Disorder Eating ...

  7. Standards in education

    OpenAIRE

    Darko Zupanc

    2005-01-01

    Modern educational systems are based on standards. Systems in countries all over the world differ and have different tradition, so different terms are used for similar concepts. In education, standards should have a similar role as in physics, where they are empirical and measurable. Two types of standards can be defined: content or curriculum standards and performance standards, with the latter being essential. Setting educational goals or content standards is the first step in the construct...

  8. A New Standard Pulsar Magnetosphere

    Science.gov (United States)

    Contopoulos, Ioannis; Kalapotharakos, Constantinos; Kazanas, Demosthenes

    2014-01-01

    In view of recent efforts to probe the physical conditions in the pulsar current sheet, we revisit the standard solution that describes the main elements of the ideal force-free pulsar magnetosphere. The simple physical requirement that the electric current contained in the current layer consists of the local electric charge moving outward at close to the speed of light yields a new solution for the pulsar magnetosphere everywhere that is ideal force-free except in the current layer. The main elements of the new solution are as follows: (1) the pulsar spindown rate of the aligned rotator is 23% larger than that of the orthogonal vacuum rotator; (2) only 60% of the magnetic flux that crosses the light cylinder opens up to infinity; (3) the electric current closes along the other 40%, which gradually converges to the equator; (4) this transfers 40% of the total pulsar spindown energy flux in the equatorial current sheet, which is then dissipated in the acceleration of particles and in high-energy electromagnetic radiation; and (5) there is no separatrix current layer. Our solution is a minimum free-parameter solution in that the equatorial current layer is electrostatically supported against collapse and thus does not require a thermal particle population. In this respect, it is one more step toward the development of a new standard solution. We discuss the implications for intermittent pulsars and long-duration gamma-ray bursts. We conclude that the physical conditions in the equatorial current layer determine the global structure of the pulsar magnetosphere.

  9. Charm current-current correlators in twisted mass lattice QCD

    International Nuclear Information System (INIS)

    The charm quark mass and the strong coupling constant are two of the fundamental parameters of the Standard Model and the precision of their determination has been continuously enhanced by higher order perturbative QCD calculations combined with more precise experimental data from e+-e-scattering as well as non-perturbative lattice calculations. As opposed to using experimental data to include non-perturbative effects, lattice QCD is not confined to the vector current correlator alone but additionally allows for an extension to the axial vector, scalar and pseudoscalar current correlators giving rise to a larger number of operators to extract the desired parameters from. We study the moments of the diverse charm current-current correlators in the framework of twisted mass lattice QCD with two light dynamical quarks. By matching lattice QCD results to continuum perturbation theory the strong coupling constant and the charm quark mass are extracted and compared to QCD sum rule and previous lattice calculations.

  10. Lectures on Physics Beyond the Standard Model

    OpenAIRE

    Gripaios, Ben

    2015-01-01

    These four lectures, given at the British Universities Summer School in Theoretical Elementary Particle Physics (BUSSTEPP), held in 2014 in Southampton, are a brief introduction to a selection of current topics in physics Beyond the Standard Model.

  11. Necessity of Having Philosophy of Adult Education as an Interdisciplinary Field at a Graduate Level

    OpenAIRE

    A. Zandvanian

    2010-01-01

    The aim of this paper is to introduce Philosophy of Adult Education as an interdisciplinary field at a graduate level. Currently, the field of Philosophy of Education and Adult Education are offered as two independent fields at some universities .This paper strives to create a link between Adult Education and Philosophy of Education. In this paper, a hundredyear history of philosophical studies in adult education has been reviewed. Although the major topics in Philosophy of Adult Education...

  12. Adult attachment styles

    Directory of Open Access Journals (Sweden)

    Maša Žvelc

    2007-01-01

    Full Text Available Theory of attachment primarily described early relationships between a child and his caretakers. In the last twenty years there is a growing interest in adult attachment research. Theories and research findings of adult attachment stem from two different methodological approaches. The first approach measures adult attachment through Adult Attachment Interview (AAI; Main, 1991 where the attachment is assessed through the narratives of adult people of their early child experiences with their primary caretakers. The second approach measures adult attachment with the help of self-evaluative questionnaires, developed by (a Hazan and Shaver (1987 who started this approach in the field of personality and social psychology, and (b Bartholomew and Horowitz (1991. Research shows that there is significant correlation between early and adult attachment style. Attachment styles are passed from generation to generation. Basic adult attachment styles are: securely attached, preoccupied, fearful-avoidant, dismissing-avoidant and disorganized. Previous research using Barholomew and Horowitz (1991 Relationship Questionnaire on 176 Slovenian students showed that 48% students are securely attached, 29% are fearful-avoidant, 10% are dismissing-avoidant, and 13% have preoccupied attachment style. Theory of attachment is very useful for understanding the behavior and subjective experiences of children and adults. It is applicable to different contexts (psychotherapy, counseling, education .... The paper proposes further research focused on integration of adult attachment styles and types of object relations measured by Test of object relations (Žvelc, 1998 and Pictorial test of Separation and Individuation (Žvelc, 2003.

  13. Current Trends in Higher Education Technology: Simulation

    Science.gov (United States)

    Damewood, Andrea M.

    2016-01-01

    This paper is focused on how technology in use changes over time, and the current trend of simulation technology as a supported classroom technology. Simulation-based training as a learning tool is discussed within the context of adult learning theories, as is the technology used and how today's higher education technology administrators support…

  14. UNESCO, adult education and political mobilization

    DEFF Research Database (Denmark)

    Milana, Marcella

    2014-01-01

    In this article the author examine the type of mobilization processes that occur via inter-actions between the UNESCO and other political actors, and how these processes led to the creation of standard-setting and monitoring instruments, like the Belèm Framework for Action (UNESCO 2009) and the G......In this article the author examine the type of mobilization processes that occur via inter-actions between the UNESCO and other political actors, and how these processes led to the creation of standard-setting and monitoring instruments, like the Belèm Framework for Action (UNESCO 2009......) and the Global Report on Adult Learning and Education (UIL 2003, 2013). The findings point at three concurrent processes or modes of mobilization in adult education: landmarking, brokering and framing. Landmarking refers to the process of co-constructing a shared past for a broad set of actors with policy...... will in adult education; Brokering captures the process of supporting the transaction of values, ideas and information to envision a viable future for adult education; finally framing addresses the structuring of information and intentions to produce materials changes at governmental level in the field of adult...

  15. Taking Current Antiretroviral Drugs

    Science.gov (United States)

    ... INHIBITORS INTEGRASE INHIBITORS 1. NUCLEOSIDE AND NUCLEOTIDE ANALOG REVERSE TRANSCRIPTASE INHIBITORS (NUKES) DRUG DAILY PILLS (ADULTS) HOW TO TAKE & ... Don't combine with d4T. 2. NON-NUCLEOSIDE REVERSE TRANSCRIPTASE INHIBITORS** (NNRTIs or NON-NUKES) DRUG DAILY PILLS (Adults)* ...

  16. Advances in the Care of Adults With Congenital Heart Disease.

    Science.gov (United States)

    Nasr, Viviane G; Kussman, Barry D

    2015-09-01

    The significant decline in mortality among children and adolescents with congenital heart disease (CHD) is associated with an increasing prevalence of CHD in adults, particularly those with moderate to severe defects. As a significant percentage of adolescents and young adults are lost to follow-up in the transition from pediatric to adult care, they may present for elective procedures with substantial CHD-associated morbidity. In addition to the specific cardiac defect, the procedures performed, and the current pathophysiological status, several factors should be considered when managing the adult with CHD. These include the type of setting (adult vs pediatric institution); surgeon (pediatric vs adult cardiac surgeon); coexisting diseases associated with CHD, such as coronary artery disease, hepatic dysfunction, renal dysfunction, cerebrovascular accidents, myopathy, and coagulation disorders; acquired diseases of aging; pregnancy; and psychosocial functioning. The current status of the management of common and important congenital cardiac defects is also described. PMID:25542866

  17. Creating standards: Creating illusions?

    DEFF Research Database (Denmark)

    Linneberg, Mai Skjøtt

    written standards may open up for the creation of illusions. These are created when written standards' content is not in accordance with the perception standard adopters and standard users have of the specific practice phenomenon's content. This general theoretical argument is exemplified by the specific...

  18. Arizona Academic Standards: Kindergarten

    Science.gov (United States)

    Arizona Department of Education, 2009

    2009-01-01

    This publication contains Arizona public schools' academic standards for kindergarten. The contents of this document include the following: (1) The Arts Standard 2006--Kindergarten; (2) Comprehensive Health Education/Physical Activity Standards 1997--Readiness (Kindergarten); (3) Foreign and Native Language Standards 1997--Readiness…

  19. 77 FR 37923 - Comment Request for Information Collection for the Workforce Investment Act (WIA) Adult and...

    Science.gov (United States)

    2012-06-25

    ... Investment Act (WIA) Adult and Dislocated Worker Programs Gold Standard Evaluation (WIA Evaluation); New...--adults and dislocated workers in this group can receive any WIA service for which they are eligible; (2) the core-and-intensive group--adults and dislocated workers in this group can receive any...

  20. Weak Interactions: From Current-Current to Standard Model and Beyond

    OpenAIRE

    Mohapatra, Rabindra N.

    2012-01-01

    Comment: 26 pages; Versions of this article will appear as a chapter in the book "Hundred years of sub-atomic physics" edited by Ernest Henley, to be published by World Scientific Publishing and as an article in International Journal of Theoretical Physics, WSPC (2012)

  1. Standardization and the European Standards Organisations

    Directory of Open Access Journals (Sweden)

    Marta Orviska

    2014-01-01

    Full Text Available Standardization is a relatively neglected aspect of the EU regulatory process and yet it is fundamental to that process and arguably has recently been the key vehicle in making the single market an economic reality. Yet the key standardization bodies in the EU, the ESOs, are scarcely known to the public and seldom discussed in the literature. In this article we redress this imbalance, arguing that standardization and integration are closely related concepts. We also argue that the ESOs have developed a degree of autonomy in expanding the boundaries of standardization and even in developing their own links with the rest of the world. Recent proposals put forward by the European Commission can be seen as an attempt to reduce that autonomy. These proposals emphasize the speed of, and stakeholder involvement in, standards production, which we further suggest are somewhat conflicting aims.

  2. Provision of Transition Education and Referral Patterns from Pediatric Cardiology to Adult Cardiac Care.

    Science.gov (United States)

    Harbison, Anna L; Grady, Stafford; Chi, Kevin; Fernandes, Susan M

    2016-02-01

    ACC/AHA guidelines recommend a structured preparation for and transfer to adult-oriented cardiac care for adult survivors of pediatric onset heart disease (POHD). Given this, we sought to describe the transition and transfer practices for a cohort of young adults with POHD and to determine factors associated with successful transfer to adult-oriented cardiac care. We performed a single-center, retrospective chart review on patients ≥18 years of age, with POHD likely to require lifelong cardiac care, who were seen in outpatient pediatric cardiology (PC) between 2008 and 2011. Successful transfer was defined as the subsequent attendance at adult cardiology (AC) within 2 years of PC visit. We identified 118 patients who met study criteria. Mean age 22.4 ± 2.0 years, 59 % male, 64 % white and 40 % Hispanic. Mean transition education topics noted was 3.3 ± 1.8 out of 20 and covered the underlying cardiac disease (89 %), follow-up and current medications (56 %) and exercise limitations (34 %). Recommendations for follow-up were AC (57 %) and PC (33 %). Of those told to transfer to AC, 79 % successfully transferred. Characteristics of successful transfer included: prior cardiac surgery (p = 0.008), cardiac medication use (p = 0.006) and frequency of follow-up ≤1 year (p = 0.037). One-quarter of all subjects did not follow-up within at least 2 years. Despite published guidelines, transition education appears lacking and the approach to transfer to adult cardiac care is not consistent. Given the increased risk of morbidity and mortality in this patient population, standardization of transition education and transfer processes appear warranted. PMID:26385471

  3. Riparian forestry management and adult stream insects

    Directory of Open Access Journals (Sweden)

    R. A. Briers

    2004-01-01

    Full Text Available The impacts of coniferous plantation forestry on the biology of upland streams in the UK are firmly established. Whilst benthic communities have been well studied, very little research has considered the impacts of riparian forestry management on adult stream insects, yet the essentially terrestrial adult (reproductive phase may be important in determining the abundance and distribution of larval stages. Riparian vegetation has a potentially strong impact on survival and success of adult stages through alteration of microclimate, habitat structure and potential food sources, in addition to effects carried over from larval stages. Here, current riparian management strategies are analysed in the light of available information on the ecology of adult stream insects. On the whole, management practices appear to favour adult stream insects, although an increase in tree cover in riparian areas could be beneficial, by providing more favourable microclimatic conditions for adults. This conclusion is drawn based on rather limited information, and the need for further research into the effects of riparian forestry management on adult stream insects is highlighted. Keywords: microclimate, plantation, life history, riparian vegetation

  4. The Dynamics of Standardization

    DEFF Research Database (Denmark)

    Brunsson, Nils; Rasche, Andreas; Seidl, David

    2012-01-01

    This paper suggests that when the phenomenon of standards and standardization is examined from the perspective of organization studies, three aspects stand out: the standardization of organizations, standardization by organizations and standardization as (a form of) organization. Following a...... comprehensive overview of existing research in these three areas, we argue that the dynamic aspects of standardization are under-represented in the scholarly discourse. Furthermore, we identify the main types of tension associated with standardization and the dynamics they generate in each of those three areas......, and show that, while standards and standardization are typically associated with stability and sameness, they are essentially a dynamic phenomenon. The paper highlights the contributions of this special issue to the topic of standards as a dynamic phenomenon in organization studies and makes...

  5. ACOUSTICAL STANDARDS NEWS.

    Science.gov (United States)

    Stremmel, Neil; Struck, Christopher J

    2016-07-01

    American National Standards (ANSI Standards) developed by Accredited Standards Committees S1, S2, S3, S3/SC 1, and S12 in the areas of acoustics, mechanical vibration and shock, bioacoustics, animal bioacoustics, and noise, respectively, are published by the Acoustical Society of America (ASA). In addition to these standards, ASA publishes a catalog of Acoustical American National Standards. To receive a copy of the latest Standards catalog, please contact Neil Stremmel.Comments are welcomed on all material in Acoustical Standards News.This Acoustical Standards News section in JASA, as well as the National Catalog of Acoustical Standards and other information on the Standards Program of the Acoustical Society of America, are available via the ASA home page: http://acousticalsociety.org. PMID:27475185

  6. Display standards for commercial flight decks

    Science.gov (United States)

    Lamberth, Larry S.; Penn, Cecil W.

    1994-06-01

    SAE display standards are used as guidelines for certifying commercial airborne electronic displays. The SAE document generation structure and approval process is described. The SAE committees that generate display standards are described. Three SAE documents covering flat panel displays (AS-8034, ARP-4256, and ARP-4260) are discussed with their current status. Head-Up Display documents are also in work.

  7. American History's Problem with Standardized Testing

    Science.gov (United States)

    McCoog, Ian J.

    2005-01-01

    This article looks at current research concerning how students best learn the discipline of history, commentaries both in favor of and against standardized testing, and basic philosophical beliefs about the discipline. It explains methods of how to incorporate differentiated lessons and performance based assessments to NCLB standards and…

  8. China's High-technology Standards Development

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    There are several major technology standards, including audio video coding (AVS), automotive electronics, third generation (3G) mobile phones, mobile television, wireless networks and digital terrestrial television broadcasting, that have been released or are currently under development in China. This article offers a detailed analysis of each standard and studies their impact on China's high-technology industry.

  9. Construct Validation of Content Standards for Teaching

    Science.gov (United States)

    van der Schaaf, Marieke F.; Stokking, Karel M.

    2011-01-01

    Current international demands to strengthen the teaching profession have led to an increased development and use of professional content standards. The study aims to provide insight in the construct validity of content standards by researching experts' underlying assumptions and preferences when participating in a delphi method. In three rounds 21…

  10. Charm Changing Neutral Currents and Supersymmetry

    OpenAIRE

    Lau, Kwong

    2003-01-01

    Flavor changing neutral currents (FCNCs) in the charm system are highly suppressed in the standard model (SM). The theoretical strategies used to suppress FCNCs induced by supersymmetry in the strange and beauty systems need not apply to the charm system. The charm changing neutral current decay D^0-> mu^+ mu^- is studied phenomenologically in the framework of supersymmetric extensions of the standard model. It is found that the decay branching ratio can be enhanced to about 10^{-10}, by havi...

  11. Neutrinophilic Non-Standard Interactions

    CERN Document Server

    Farzan, Yasaman

    2016-01-01

    We construct UV-complete models for non-standard neutrino interactions mediated by a sub-GeV gauge boson Z' coupled to baryon number $B$ or $B-L$. A flavor-dependent Z' coupling to neutrinos is induced by mixing a U(1)'-charged Dirac fermion with the active neutrinos, naturally suppressing flavor violation or non-universality of the charged leptons to the loop level. We show that these models can give rise to large flavor-conserving as well as flavor-violating non-standard neutral-current neutrino interactions potentially observable in current or future oscillation experiments such as DUNE without being in conflict with other constraints such as neutrino scattering or lepton-flavor-violating decays. In particular, the LMA-Dark solution to the solar-neutrino anomaly can be obtained for $U(1)_B$, but not for $U(1)_{B-L}$.

  12. Becoming Adult Educators in theNordic-Baltic Region

    DEFF Research Database (Denmark)

    Milana, Marcella; Larson, Anne

    With the increased concerned for lifelong learning comes a higher political attention on adult education and training. Hence on the creation of opportunity structures for adults to engage in intentional learning as well as on the professionalization of those who serve the public good by educating...... of the available variety of courses and programs dealing with adult learning, only few are meant to represent pre-service education and training for prospective teachers of adults. At a first glance, people willing to qualify as adult educators seems to have several opportunities to do so, since the Danish adult...... education and training system also provide a variety of courses and programs in adult learning, corresponding to short-, medium- and long-cycle higher education. By deepening the analysis, however, it is possible to observe several pitfalls in the system. Current provision is characterised by a differential...

  13. Strokes in young adults: epidemiology and prevention

    Directory of Open Access Journals (Sweden)

    Smajlović D

    2015-02-01

    Full Text Available Dževdet Smajlović Department of Neurology, University Clinical Centre Tuzla, School of Medicine, University of Tuzla, Bosnia and Herzegovina Abstract: Strokes in young adults are reported as being uncommon, comprising 10%–15% of all stroke patients. However, compared with stroke in older adults, stroke in the young has a disproportionately large economic impact by leaving victims disabled before their most productive years. Recent publications report an increased incidence of stroke in young adults. This is important given the fact that younger stroke patients have a clearly increased risk of death compared with the general population. The prevalence of standard modifiable vascular risk factors in young stroke patients is different from that in older patients. Modifiable risk factors for stroke, such as dyslipidemia, smoking, and hypertension, are highly prevalent in the young stroke population, with no significant difference in geographic, climatic, nutritional, lifestyle, or genetic diversity. The list of potential stroke etiologies among young adults is extensive. Strokes of undetermined and of other determined etiology are the most common types among young patients according to TOAST (Trial of Org 10172 in Acute Stroke Treatment criteria. Prevention is the primary treatment strategy aimed at reducing morbidity and mortality related to stroke. Therefore, primary prevention is very important with regard to stroke in young adults, and aggressive treatment of risk factors for stroke, such as hypertension, smoking, and dyslipidemia, is essential. The best form of secondary stroke prevention is directed toward stroke etiology as well as treatment of additional risk factors. However, there is a lack of specific recommendations and guidelines for stroke management in young adults. In conclusion, strokes in young adults are a major public health problem and further research, with standardized methodology, is needed in order to give us more

  14. Neutrino and The Standard Model

    CERN Document Server

    Bilenky, S M

    2014-01-01

    After discovery of the Higgs boson at CERN the Standard Model acquired a status of the full, correct theory of the elementary particles in the electroweak range. What general conclusions can be inferred from the SM? I am suggesting here that in the framework of such general principles as local gauge symmetry, unification of the weak and electromagnetic interactions and Brout-Englert-Higgs spontaneous breaking of the electroweak symmetry nature chooses the simplest possibilities. It is very plausible that massless left-handed neutrinos (simplest, most economical possibility) play crucial role in the determination of the charged current structure of the Standard Model and that neutrino properties (masses and nature) are determined by a beyond the Standard Model physics. The discovery of the neutrinoless double $\\beta$-decay and proof that neutrinos with definite masses are Majorana particles would be an important evidence in favor of the considered scenario.

  15. Mindfulness-based intervention for prodromal sleep disturbances in older adults: design and methodology of a randomized controlled trial.

    Science.gov (United States)

    Black, David S; O'Reilly, Gillian A; Olmstead, Richard; Breen, Elizabeth C; Irwin, Michael R

    2014-09-01

    Sleep problems are prevalent among older adults, often persist untreated, and are predictive of health detriments. Given the limitations of conventional treatments, non-pharmacological treatments such as mindfulness-based interventions (MBIs) are gaining popularity for sleep ailments. However, nothing is yet known about the impact of MBIs on sleep in older adults with prodromal sleep disturbances. This article details the design and methodology of a 6-week parallel-group RCT calibrated to test the treatment effect of the Mindful Awareness Practices (MAPs) program versus sleep hygiene education for improving sleep quality, as the main outcome, in older adults with prodromal sleep disturbances. Older adults with current sleep disturbances will be recruited from the urban Los Angeles community. Participants will be randomized into two standardized treatment conditions, MAPs and sleep hygiene education. Each condition will consist of weekly 2-hour group-based classes over the course of the 6-week intervention. The primary objective of this study is to determine if mindfulness meditation practice as engaged through the MAPs program leads to improved sleep quality relative to sleep hygiene education in older adults with prodromal sleep disturbances.

  16. Adult congenital heart disease

    OpenAIRE

    Morphet, John AM

    2006-01-01

    One million people over the age of 20 suffer from congenital heart disease in the United States. These adult patients can slip through the cracks of our medical system; many are too old to be cared for in most pediatric institutions by pediatric cardiologists and, unfortunately, most adult cardiologists are not trained in congenital heart disease. Therefore, it is important to identify the common lesions in adult congenital heart disease and how they should be managed. Acyanotic congenital he...

  17. Culture And Adult Immigrants

    OpenAIRE

    Andersen, Tamar Barbara; Fogde, Anne-Sofie; Rasmussen, Ditte Ninna; Uski, Juha Janne Olavi

    2005-01-01

    "Culture and adult immigrants" is a project about integration of adult immigrants into the Danish society. It is based on an integration theory by Charlotte Hamburger and a culture theory by Thomas Hylland Eriksen and Torunn Arntsen Sørheim. The two theories conclude in a joined analysis of language school material from the language centre of Roskilde, in search for an answer to the question if and how the Danish language education supports the integration of adult immigrants into the D...

  18. Lead toxicity: Current concerns

    Energy Technology Data Exchange (ETDEWEB)

    Goyer, R.A. (Univ. of Western Ontario, London (Canada))

    1993-04-01

    Over the 20-year period since the first issue of Environmental Health Perspectives was published, there has been considerable progress in the understanding of the potential toxicity of exposure to lead. Many of these advances have been reviewed in published symposia, conferences, and review papers in EHP. This brief review identifies major advances as well as a number of current concerns that present opportunities for prevention and intervention strategies. The major scientific advance has been the demonstration that blood lead (PbB) levels of 10-15 micrograms/dL in newborn and very young infants result in cognitive and behavioral deficits. Further support for this observation is being obtained by prospective or longitudinal studies presently in progress. The mechanism(s) for the central nervous system effects of lead is unclear but involve lead interactions within calcium-mediated intracellular messenger systems and neurotransmission. Effects of low-level lead exposure on blood pressure, particularly in adult men, may be related to the effect of lead on calcium-mediated control of vascular smooth muscle contraction and on the renin-angiotensin system. Reproductive effects of lead have long been suspected, but low-level effects have not been well studied. Whether lead is a carcinogen or its association with renal adenocarcinoma is a consequence of cystic nephropathy is uncertain. Major risk factors for lead toxicity in children in the United States include nutrition, particularly deficiencies of essential metals, calcium, iron, and zinc, and housing and socioeconomic status. A goal for the year 2000 is to reduce prevalence of blood lead levels exceeding 15 micrograms/dL. 97 refs.

  19. Current Concept of Geometrical Accuracy

    Directory of Open Access Journals (Sweden)

    Görög Augustín

    2014-06-01

    Full Text Available Within the solving VEGA 1/0615/12 research project "Influence of 5-axis grinding parameters on the shank cutter´s geometric accuracy", the research team will measure and evaluate geometrical accuracy of the produced parts. They will use the contemporary measurement technology (for example the optical 3D scanners. During the past few years, significant changes have occurred in the field of geometrical accuracy. The objective of this contribution is to analyse the current standards in the field of geometric tolerance. It is necessary to bring an overview of the basic concepts and definitions in the field. It will prevent the use of outdated and invalidated terms and definitions in the field. The knowledge presented in the contribution will provide the new perspective of the measurement that will be evaluated according to the current standards.

  20. Measuring Adult Literacy Students' Reading Skills Using the Gray Oral Reading Test

    Science.gov (United States)

    Greenberg, Daphne; Pae, Hye Kyeong; Morris, Robin D.; Calhoon, Mary Beth; Nanda, Alice O.

    2009-01-01

    There are not enough reading tests standardized on adults who have very low literacy skills, and therefore tests standardized on children are frequently administered. This study addressed the complexities and problems of using a test normed on children to measure the reading comprehension skills of 193 adults who read at approximately third…