WorldWideScience

Sample records for ads related studies

  1. Revisiting the thermodynamic relations in AdS /CMT models

    Science.gov (United States)

    Hyun, Seungjoon; Park, Sang-A.; Yi, Sang-Heon

    2017-03-01

    Motivated by the recent unified approach to the Smarr-like relation of anti-de Sitter (AdS) planar black holes in conjunction with the quasilocal formalism on conserved charges, we revisit the quantum statistical and thermodynamic relations of hairy AdS planar black holes. By extending the previous results, we identify the hairy contribution in the bulk and show that the holographic computation can be improved so that it is consistent with the bulk computation. We argue that the first law can be retained in its universal form and that the relation between the on-shell renormalized Euclidean action and its free energy interpretation in gravity may also be undeformed even with the hairy contribution in hairy AdS black holes.

  2. Neutron cross section measurements at n-TOF for ADS related studies

    CERN Document Server

    Mastinu, P F; Aerts, G; Alvarez, H; Alvarez-Velarde, F; Andriamonje, Samuel A; Andrzejewski, J; Assimakopoulos, P A; Audouin, L; Badurek, G; Bustreo, N; Aumann, P; Beva, F; Berthoumieux, E; Calviño, F; Cano-Ott, D; Capote, R; Carillo de Albornoz, A; Cennini, P; Chepel, V; Chiaveri, Enrico; Colonna, N; Cortés, G; Couture, A; Cox, J; Dahlfors, M; David, S; Dillmann, I; Dolfini, R; Domingo-Pardo, C; Dridi, W; Durán, I; Eleftheriadis, C; Segura, M E; Ferrant, L; Ferrari, A; Ferreira-Marques, R; itzpatrick, L; Frais-Kölbl, H; Fujii, K; Furman, W; Guerrero, C; Gonçalves, I; Gallino, R; González-Romero, E M; Goverdovski, A; Gramegna, F; Griesmayer, E; Gunsing, F; Haas, B; Haight, R; Heil, M; Herrera-Martínez, A; Igashira, M; Isaev, S; Jericha, E; Kadi, Y; Käppeler, F K; Karamanis, D; Karadimos, D; Kerveno, M; Ketlerov, V; Köhler, P; Konovalov, V; Kossionides, E; Krticka, M; Lamboudis, C; Leeb, H; Lindote, A; Lopes, I; Lozano, M; Lukic, S; Marganiec, J; Marques, L; Marrone, S; Massimi, C; Mengoni, A; Milazzo, P M; Moreau, C; Mosconi, M; Neves, F; Oberhummer, Heinz; O'Brien, S; Oshima, M; Pancin, J; Papachristodoulou, C; Papadopoulos, C; Paradela, C; Patronis, N; Pavlik, A; Pavlopoulos, P; Perrot, L; Plag, R; Plompen, A; Plukis, A; Poch, A; Pretel, C; Quesada, J; Rauscher, T; Reifarth, R; Rosetti, M; Rubbia, Carlo; Rudolf, G; Rullhusen, P; Salgado, J; Sarchiapone, L; Savvidis, I; Stéphan, C; Tagliente, G; Taín, J L; Tassan-Got, L; Tavora, L; Terlizzi, R; Vannini, G; Vaz, P; Ventura, A; Villamarín, D; Vincente, M C; Vlachoudis, V; Vlastou, R; Voss, F; Walter, S; Wendler, H; Wiescherand, M; Wisshak, K

    2006-01-01

    A neutron Time-of-Flight facility (n_TOF) is available at CERN since 2001. The innovative features of the neutron beam, in particular the high instantaneous flux, the wide energy range, the high resolution and the low background, make this facility unique for measurements of neutron induced reactions relevant to the field of Emerging Nuclear Technologies, as well as to Nuclear Astrophysics and Fundamental Nuclear Physics. The scientific motivations that have led to the construction of this new facility are here presented. The main characteristics of the n_TOF neutron beam are described, together with the features of the experimental apparata used for cross-section measurements. The main results of the first measurement campaigns are presented. Preliminary results of capture cross-section measurements of minor actinides, important to ADS project for nuclear waste transmutation, are finally discussed.

  3. Neutron time-of-flight spectrometer based on HIRFL for studies of spallation reactions related to ADS project

    Institute of Scientific and Technical Information of China (English)

    张苏雅拉吐; 罗飞; 陈志强; 韩瑞; 刘星泉; 林炜平; 刘建立; 石福栋; 任培培; 田国玉

    2015-01-01

    A Neutron Time-of-Flight (NTOF) spectrometer, based at the Heavy Ion Research Facility in Lanzhou (HIRFL) was developed for studies of neutron production of proton induced spallation reactions related to the ADS project. After the presentation of comparisons between calculated spallation neutron production double-differential cross sections and the available experimental data, a detailed description of the NTOF spectrometer is given. Test beam results show that the spectrometer works well and data analysis procedures are established. The comparisons of the test beam neutron spectra with those of GEANT4 simulations are presented.

  4. Implementation of Recursion Relations in Gluon Scattering Amplitude Calculations in AdS4 /CFT3

    Science.gov (United States)

    Dokmetzoglou, Nikolaos; Kharel, Savan

    2017-01-01

    The Anti-de Sitter/Conformal Field Theory (AdS/CFT) correspondence is a duality between a theory of gravity in curved-space (AdS) and a conformally-invariant quantum field theory in flat-space (CFT). Scattering amplitudes are observables associated with the probability of the interaction of a given assembly of particles. Gluons, being the exchange particles associated with the strong nuclear force, which holds quarks together to form protons, are abundant byproducts of fundamental particle collisions. Thus, studying gluon scattering amplitudes is an effective way of deepening our understanding of these observables in AdS/CFT. Traditionally, Feynman diagrams have been used to calculate such scattering amplitudes. In this project, we use factorization properties and recursion relations to simplify these calculations. More specifically, we calculate multiple (different helicity combinations) four-point gluon scattering amplitudes in AdS4 /CFT3 (4-D AdS and 3-D CFT) as sums of products of three-point amplitudes. And then we calculate a five-point gluon scattering amplitude in AdS4 /CFT3 by decomposing it into a sum of products of these four-point and three-point amplitudes. Finally we comment on useful identities for checking these amplitudes. This work was supported by a Weinstein Davidson College Research Initiative Summer Research grant.

  5. Comparative study of effects of bone marrow cell vs. Ad5-HGF administration via non infarct-related artery injection in myocardial infarction in swine

    Institute of Scientific and Technical Information of China (English)

    Liansheng Wang; Jun Huang; Zhijian Yang; Wei Wang; Dongchao Ma; Shunlin Xu; Yuqing Zhang; Fang Zhou; Bo Chen; Kejiang Cao

    2007-01-01

    Objective: To evaluate the effect of transplanting bone marrow-derived mesenchymal stem cells (BM-MSCs) or adenovirus5-hepatocyte growth factor(Ad5-HGF) via non-infarct-related artery injection in swine myocardial infarction models. Methods :BMMSCs were obtained from swine bone marrow and expanded in vitro to a purity of >50%. A myocardial infarction(MI) was created by ligating the distal left anterior descending artery in swine. Either BM-MSCs (5 × 106/ml) or Ad5-HGF (4 × 109 pfu) were transfused via the right coronary artery (non-infarcted artery) four weeks after MI. Gate-controled cardiac perfusion imaging was performed at the end of four and seven weeks after LAD ligation, to evaluate heart function and cardiac perfusion. Morphologic and histologic characteristics of the hearts were also studied. Results: (1)The gate-controlled cardiac perfusion imaging showed that the improvement in LVEF was greater in both treatment groups than in control group at the 4th weeks. (2)In both treatment groups, capillary density was significantly higher than that of control group (P < 0.05). Conclusion:BM-MSCs or Ad5-HGF transplantation via non-infarcted artery administration can stimulate angiogenesis and improve heart function, but there was no difference in therapeutic efficacy between BM-MSCs and Ad5-HGF.

  6. The activities of HPPA technology related to ADS in China

    CERN Document Server

    Guan Xia Ling; Ding Da Zhao; Fang Jia Xun; Fang Shou Xian; Fu Shin Ian; Guo, Z Y; Jiang Wei; Li Jie Quan; Luo Zi Hua; Ouyang Hua Fu; Peng Chao Hua; Xu Tao Guang; Xu Wen Wu; Yu Qi; Zhang Zong Hua; Zhao Sheng Chu

    2001-01-01

    High Power Proton Accelerator (HPPA) is being studied all over world for numerous applications, which includes the waste transmutation, spallation neutron source and material irradiation facilities. In China, a multi-purpose verification system as a first phase of Chinese ADS program consists of a low energy accelerator (150 MeV/3 mA proton linac) and a swimming pool light water sub-critical reactor. The activities of HPPA technology related to ADS in China, which includes the intense proton ECR source, the RFQ accelerator and some other technology of HPPA, are described

  7. Relational Resources in Value Adding Webs

    DEFF Research Database (Denmark)

    Gretzinger, Susanne; Royer, Susanne

    2014-01-01

    The fact that the main source of value creation is rooted within networks raises the question of the impact of social capital on relational rents. The main objectives of this paper therefore are to investigate how value creation on the relational level of a cluster can be systematised to come...... the high value of informal cluster structures. The paper develops implications for the cluster firms as well as the cluster management in its role as a broker and a moderator....

  8. Health-related ad information and health motivation effects on product evaluations

    DEFF Research Database (Denmark)

    Chrysochou, Polymeros; Grunert, Klaus G

    2014-01-01

    This study tests the effect of health-related ad information on perceived product healthfulness and purchase intention. Also, the study investigates whether consumers' health motivation moderates the effects, because of the way health motivation affects processing of health-related information...... evaluations, while functional claims and process claims have much smaller effects. Health motivation shows significant interaction with process claims on product evaluations....... in ads. Three types of healthrelated ad elements are distinguished: functional claims, process claims and health imagery. These elements were combined in mock ads and an online experiment was run to test the study hypotheses. Results show that health imagery has the largest impact on consumers' product...

  9. Boundary conditions for General Relativity on AdS3 and the KdV hierarchy

    Science.gov (United States)

    Pérez, Alfredo; Tempo, David; Troncoso, Ricardo

    2016-06-01

    It is shown that General Relativity with negative cosmological constant in three spacetime dimensions admits a new family of boundary conditions being labeled by a nonnegative integer k. Gravitational excitations are then described by "boundary gravitons" that fulfill the equations of the k-th element of the KdV hierarchy. In particular, k = 0 corresponds to the Brown-Henneaux boundary conditions so that excitations are described by chiral movers. In the case of k = 1, the boundary gravitons fulfill the KdV equation and the asymptotic symmetry algebra turns out to be infinite-dimensional, abelian and devoid of central extensions. The latter feature also holds for the remaining cases that describe the hierarchy ( k > 1). Our boundary conditions then provide a gravitational dual of two noninteracting left and right KdV movers, and hence, boundary gravitons possess anisotropic Lifshitz scaling with dynamical exponent z = 2 k + 1. Remarkably, despite spacetimes solving the field equations are locally AdS, they possess anisotropic scaling being induced by the choice of boundary conditions. As an application, the entropy of a rotating BTZ black hole is precisely recovered from a suitable generalization of the Cardy formula that is compatible with the anisotropic scaling of the chiral KdV movers at the boundary, in which the energy of AdS spacetime with our boundary conditions depends on z and plays the role of the central charge. The extension of our boundary conditions to the case of higher spin gravity and its link with different classes of integrable systems is also briefly addressed.

  10. Boundary conditions for General Relativity on AdS$_{3}$ and the KdV hierarchy

    CERN Document Server

    Pérez, Alfredo; Troncoso, Ricardo

    2016-01-01

    It is shown that General Relativity with negative cosmological constant in three spacetime dimensions admits a new family of boundary conditions being labeled by a nonnegative integer $k$. Gravitational excitations are then described by "boundary gravitons" that fulfill the equations of the $k$-th element of the KdV hierarchy. In particular, $k=0$ corresponds to the Brown-Henneaux boundary conditions so that excitations are described by chiral movers. In the case of $k=1$, the boundary gravitons fulfill the KdV equation and the asymptotic symmetry algebra turns out to be infinite-dimensional, abelian and devoid of central extensions. The latter feature also holds for the remaining cases that describe the hierarchy ($k>1$). Our boundary conditions then provide a gravitational dual of two noninteracting left and right KdV movers, and hence, boundary gravitons possess anisotropic Lifshitz scaling with dynamical exponent $z=2k+1$. Remarkably, despite spacetimes solving the field equations are locally AdS, they po...

  11. Rural Location and Relative Location: Adding Community Context to the Study of Sexual Assault Survivor Time Until Presentation for Medical Care.

    Science.gov (United States)

    Johnson, Ingrid Diane; Hiller, Matthew L

    2016-08-12

    Despite a strong empirical base linking community context and proximity to resources to individual health care access, studies examining predictors of sexual assault survivor time until presentation for medical care have not yet examined these relationships. This study addresses this gap. The data included retrospective records on a sample of 1,630 female survivors who reported their sexual assault to law enforcement and were subsequently seen by a sexual assault nurse examiner (SANE) in one of eight Alaskan communities between the years 1996 and 2006. Logistic regression models were used to determine whether delays in presentation (presentation 12 hr or more after assault) differed for women presenting in unique communities (rural location), and between those whose assault and exam occurred in different communities versus occurring in the same community (relative location). Although rural location did not seem to have a unique impact on time until presentation, differing locations (i.e., relative location) of assaults and exams increased the likelihood of delays in presentation. Non-American Indian/Alaska Native race/ethnicity and knowing one's assailant(s) also increased the likelihood of delays. These results indicate that in addition to a need for further research, there is a need for more appropriate and reliable sexual assault medical services across communities, and that survivors assaulted by known assailants should be targeted in efforts to reduce time until presentation.

  12. Study of ADS-B Data Evaluation

    Institute of Scientific and Technical Information of China (English)

    ZHANG Jun; LIU Wei; ZHU Yanbo

    2011-01-01

    In western China,the terrain and meteorological conditions are so complex that it is not suitable to construct new radar stations.Automatic dependent surveillance-broadcast(ADS-B) is a totally new surveillance method,so before practically applied and operated in China,abundant tests and evaluations are necessary to validate the performance of ADS-B and guarantee the operational security.During the flight tests,we collect the data of radar,ADS-B and high accuracy position and compare the performance of ADS-B with radar based on high accuracy position.To solve the asynchronous problem among radar data,ADS-B data and real-time kinematic(RTK) data caused by different update rates,this article proposes the technique of synchronizing multi-surveil- lance data by extrapolating from the data of low update rate to high update rate according to velocity and heading.Meanwhile,because radar data,ADS-B data and RTK data are expressed in different coordinates and cannot be compared each other,this article provides a method to unifying the coordinates of multi-surveillance data.By the analysis and evaluation,we can conclude that the performance of ADS-B is better than radar.

  13. Quantum dispersion relations for excitations of long folded spinning superstring in AdS_5 x S^5

    CERN Document Server

    Giombi, S; Roiban, R; Tseytlin, A A

    2010-01-01

    We use AdS_5 x S^5 superstring sigma model perturbation theory to compute the leading one-loop corrections to the dispersion relations of the excitations near a long spinning string in AdS. This investigation is partially motivated by the OPE-based approach to the computation of the expectation value of null polygonal Wilson loops suggested in arXiv:1006.2788. Our results are in partial agreement with the recent asymptotic Bethe ansatz computation in arXiv:1010.5237. In particular, we find that the heaviest AdS mode (absent in the ABA approach) is stable and has a corrected one-loop dispersion relation similar to the other massive modes. Its stability might hold also at the next-to-leading order as we suggest using a unitarity-based argument.

  14. Utilization of the BARC critical facility for ADS related experiments

    Indian Academy of Sciences (India)

    Rajeev Kumar; R Srivenkatesan

    2007-02-01

    The paper discusses the basic design of the critical facility, whose main purpose is the physics validation of AHWR. Apart from moderator level control, the facility will have shutdown systems based on shutoff rods and multiple ranges of neutron detection systems. In addition, it will have a flux mapping system based on 25 fission chambers, distributed in the core. We are planning to use this reactor for experiments with a suitable source to simulate an ADS system. Any desired sub-criticality can be achieved by adjusting the moderator level. Apart from perfecting our experimental techniques, in simple configurations, we intend to study the one-way coupled core in this facility. Preliminary calculations, employing a Monte Carlo code TRIPOLI, are presented.

  15. 17 CFR 240.17Ad-13 - Annual study and evaluation of internal accounting control.

    Science.gov (United States)

    2010-04-01

    ... internal accounting control. 240.17Ad-13 Section 240.17Ad-13 Commodity and Securities Exchanges SECURITIES... Company Rules § 240.17Ad-13 Annual study and evaluation of internal accounting control. (a) Accountant's... accountant concerning the transfer agent's system of internal accounting control and related procedures...

  16. Delayed collapses of BECs in relation to AdS gravity

    CERN Document Server

    Biasi, Anxo F; Paredes, Angel

    2016-01-01

    We numerically investigate spherically symmetric collapses in the Gross-Pitaevskii equation with attractive nonlinearity in a harmonic potential. Even below threshold for direct collapse, the wave function bounces off from the origin and may eventually become singular after a number of oscillations in the trapping potential. This is reminiscent of the evolution of Einstein gravity sourced by a scalar field in Anti-de Sitter space where collapse corresponds to black hole formation. We carefully examine the long time evolution of the wave function for continuous families of initial states in order to sharpen out this coincidence which may bring new insights in both directions. On one hand, we comment on possible implications for the so-called Bosenova collapses in cold atom Bose-Einstein condensates. On the other hand, Gross-Pitaevskii provides a toy model to study the relevance of either the resonance conditions or the nonlinearity for the problem of Anti-de Sitter instability.

  17. Revisit to Thermodynamic Relations in the AdS/CMT Models

    CERN Document Server

    Hyun, Seungjoon; Yi, Sang-Heon

    2016-01-01

    Motivated by the recent unified approach to the Smarr-like relation of AdS planar black holes in conjunction with the quasi-local formalism on conserved charges, we revisit the quantum statistical and thermodynamic relations of hairy AdS planar black holes. By extending the previous results, we identify the hairy contribution in the bulk and show that the holographic computation can be improved so that it is consistent with the bulk computation. We argue that the first law can be retained in its universal form while the relation between the on-shell renormalized Euclidean action and its free energy interpretation in gravity may be deformed to contain the hairy contribution in hairy AdS black holes.

  18. The Added Value of Study Abroad: Fostering a Global Citizenry

    Science.gov (United States)

    Tarrant, Michael A.; Rubin, Donald L.; Stoner, Lee

    2014-01-01

    Few studies have employed experimental designs adequate for documenting the value added of studying abroad; that is, learning outcomes above and beyond that which may be achieved in domestic or traditional campus-based courses. Using a pre-/posttest, two-by-two factor design of course location (study abroad vs. home campus) by course subject…

  19. Area Functional Relation for 5D-Gauss-Bonnet-AdS Black Hole

    CERN Document Server

    Pradhan, Parthapratim

    2016-01-01

    We present \\emph{area functional relation} and \\emph{entropy functional relation} for multi-horizon five dimensional Einstein-Maxwell-Gauss-Bonnet-AdS Black Hole. It has been observed by exact calculation that some complicated function of two or three horizons area is \\emph{mass-independent} whereas the entropy product relation is \\emph{not} mass-independent. We study the thermodynamic stability of this black hole. The phase transition occurs at certain condition. \\emph{Smarr mass formula} and \\emph{first law} of thermodynamics is also discussed. Thermodynamic product formula for 5D Einstein-Maxwell-Gauss-Bonnet black hole without Cosmological parameter is also derived in appendix. This \\emph{mass-independent} relation suggests they could turn out to be an \\emph{universal} quantity.

  20. A Study On OFDM In Mobile Ad Hoc Network

    Directory of Open Access Journals (Sweden)

    Malik Nasereldin Ahmed

    2012-06-01

    Full Text Available Orthogonal Frequency Division Multiplexing (OFDM is the physical layer in emerging wireless local area networks that are also being targeted for ad hoc networking. OFDM can be also exploited in ad hoc networks to improve the energy performance of mobile devices. It is important in wireless networks because it can be used adaptively in a dynamically changing channel. This study gives a detailed view about OFDM and how it is useful to increase the bandwidth. This paper also gives an idea about how OFDM can be a promising technology for high capacity wireless communication.

  1. Studies on Functional Yogurt with Added Inulin as Prebiotic Fiber

    Directory of Open Access Journals (Sweden)

    Mirela Jimborean

    2015-11-01

    Full Text Available Products that contain both probiotics and prebiotics are known as symbiotic, these products are able to modify the composition of the internal microflora, with the beneficial effects on the consumer's body. The objective followed in this study was the obtaining of probiotic yogurt in which inulin is added. The control consists in an organoleptic examination, a physicochemical examination and monitoring of the evolution of bifidobacteria. The results obtained showed a progressive evolution by adding inulin. The highest difference was recorded for yogurt type 3 with an addition of 3% inulin, the number of bifidobacteria increased with 1.04x109 cfu/g in only 7 days, reaching 1.30 x 109 cfu/g.

  2. Value added intellectual coefficient (VAIC: an empirical study

    Directory of Open Access Journals (Sweden)

    Mehrnaz Paknezhad

    2012-04-01

    Full Text Available There is no doubt that conventional accounting does not provide actual value of a firm since they only take into account the tangible assets. Intellectual capital provides a new concept for considering actual value of the assets, which helps calculate intangible values of the firm. In this paper, we use value added intellectual coefficient (VAIC to measure the performance of a firm. The study investigates the relationship between intellectual capital and return on assets and value added for three consecutive years between 2008 and 2010. The results indicate that there is no meaningful relationship between intellectual capital and return on assets for fiscal years of 2008 and 2009 but there is a meaningful relationship between these two items for the fiscal year of 2010 when . Our findings also indicate that there is no meaningful relationship between intellectual capital and value added for the years of 2008 and 2010 but there is a meaningful relationship between the items for the fiscal year of 2009. The results somewhat confirm the recently published results in the literature, which argues the use of VAIC for assessing the direct impact of IC on other financial factors.

  3. The added value of proteomics for toxicological studies.

    Science.gov (United States)

    Miller, I; Serchi, T; Murk, A J; Gutleb, A C

    2014-01-01

    Proteomics has the potential to elucidate complex patterns of toxic action attributed to its unique holistic a posteriori approach. In the case of toxic compounds for which the mechanism of action is not completely understood, a proteomic approach may provide valuable mechanistic insight. This review provides an overview of currently available proteomic techniques, including examples of their application in toxicological in vivo and in vitro studies. Future perspectives for a wider application of state-of-the-art proteomic techniques in the field of toxicology are discussed. The examples concern experiments with dioxins, polychlorinated biphenyls, and polybrominated diphenyl ethers as model compounds, as they exhibit a plethora of sublethal effects, of which some mechanisms were revealed via successful proteomic studies. Generally, this review shows the added value of including proteomics in a modern tool box for toxicological studies.

  4. Study of Confinement/Deconfinement Transition in AdS/QCD with Generalized Warp Factors

    Directory of Open Access Journals (Sweden)

    Shobhit Sachan

    2014-01-01

    Full Text Available We study analytical solutions of charged black holes and thermally charged AdS with generalized warped factors in Einstein-Maxwell-Dilaton system. We calculate Euclidean action for charged AdS and thermally charged AdS. The actions in both backgrounds are regularized by the method of background subtraction. The study of phase transition between charged black hole and thermally charged AdS gives an insight into the confinement/deconfinement transition. The plots of grand potential versus temperature and chemical potential versus transition temperature are obtained.

  5. On integrable deformations of superstring sigma models related to AdSn×Sn supercosets

    Directory of Open Access Journals (Sweden)

    B. Hoare

    2015-08-01

    Full Text Available We consider two integrable deformations of 2d sigma models on supercosets associated with AdSn×Sn. The first, the “η-deformation” (based on the Yang–Baxter sigma model, is a one-parameter generalization of the standard superstring action on AdSn×Sn, while the second, the “λ-deformation” (based on the deformed gauged WZW model, is a generalization of the non-abelian T-dual of the AdSn×Sn superstring. We show that the η-deformed model may be obtained from the λ-deformed one by a special scaling limit and analytic continuation in coordinates combined with a particular identification of the parameters of the two models. The relation between the couplings and deformation parameters is consistent with the interpretation of the first model as a real quantum deformation and the second as a root of unity quantum deformation. For the AdS2×S2 case we then explore the effect of this limit on the supergravity background associated with the λ-deformed model. We also suggest that the two models may form a dual Poisson–Lie pair and provide direct evidence for this in the case of the integrable deformations of the coset associated with S2.

  6. An AD-related neuroprotector rescues transformed rat retinal ganglion cells from CoCl₂-induced apoptosis.

    Science.gov (United States)

    Men, Jie; Zhang, Xiaohui; Yang, Yang; Gao, Dianwen

    2012-05-01

    Some ocular diseases characterized by apoptotic death of retinal ganglion cells (RGCs) and Alzheimer's disease (AD) are chronic neurodegenerative disorders and have similarities in neuropathology. Humanin (HN) is known for its ability to suppress neuronal death induced by AD-related insults. In present study, we investigated the neuroprotective effects of HN on hypoxia-induced toxicity in RGC-5 cells. Hypoxia mimetic compound cobalt chloride (CoCl₂) could increase the cell viability loss and apoptosis, whereas HN can significantly attenuate these effects. This finding may provide new therapeutics for the retinal neurodegenerative diseases targeting neuroprotection.

  7. The Guinea Pig as a Model for Sporadic Alzheimer's Disease (AD: The Impact of Cholesterol Intake on Expression of AD-Related Genes.

    Directory of Open Access Journals (Sweden)

    Mathew J Sharman

    Full Text Available We investigated the guinea pig, Cavia porcellus, as a model for Alzheimer's disease (AD, both in terms of the conservation of genes involved in AD and the regulatory responses of these to a known AD risk factor - high cholesterol intake. Unlike rats and mice, guinea pigs possess an Aβ peptide sequence identical to human Aβ. Consistent with the commonality between cardiovascular and AD risk factors in humans, we saw that a high cholesterol diet leads to up-regulation of BACE1 (β-secretase transcription and down-regulation of ADAM10 (α-secretase transcription which should increase release of Aβ from APP. Significantly, guinea pigs possess isoforms of AD-related genes found in humans but not present in mice or rats. For example, we discovered that the truncated PS2V isoform of human PSEN2, that is found at raised levels in AD brains and that increases γ-secretase activity and Aβ synthesis, is not uniquely human or aberrant as previously believed. We show that PS2V formation is up-regulated by hypoxia and a high-cholesterol diet while, consistent with observations in humans, Aβ concentrations are raised in some brain regions but not others. Also like humans, but unlike mice, the guinea pig gene encoding tau, MAPT, encodes isoforms with both three and four microtubule binding domains, and cholesterol alters the ratio of these isoforms. We conclude that AD-related genes are highly conserved and more similar to human than the rat or mouse. Guinea pigs represent a superior rodent model for analysis of the impact of dietary factors such as cholesterol on the regulation of AD-related genes.

  8. Construction of FFAG Accelerators in KURRI for ADS Study

    CERN Document Server

    Tanigaki, Minoru; Inoue, Makoto; Ishi, Yoshihiro; Machida, Shinji; Mishima, Kaichiro; Mori, Yoshiharu; Shiroya, Seiji

    2004-01-01

    KART (Kumatori Accelerator driven Reactor Test) project is in progress at Kyoto University Research Reactor Institute (KURRI) from the fiscal year of 2002. The purposes of this project is the feasibility study of ADS, such as studying the effect of incident neutron energy on the effective multiplication factor of the subcritical nuclear fuel system. We are now constructing a proton FFAG accelerator complex as a neutron production driver for this project. Our accelerator complex consists of a 2.5 MeV FFAG with induction acceleration as an injector, 20 MeV and 150 MeV FFAGs with RF acceleration as a booster and a main ring, respectively. Our FFAG injector is a spiral sector type with 32 trim coils to produce a magnetic field of variable field index. Both booster and main rings are the radial sector type in which the field index is determined by the shape of pole-face. The test operations of the injector and the whole FFAG complex are expected around the spring and summer in 2005, respectively. Then this FFAG co...

  9. Bace1 activity in cerebrospinal fluid and its relation to markers of ad pathology

    NARCIS (Netherlands)

    Mulder, S.D.; Flier, W.M. van der; Verheijen, J.H.; Mulder, C.; Scheltens, P.; Blankenstein, M.A.; Hack, C.E.; Veerhuis, R.

    2010-01-01

    Several studies have shown that reduced amyloid-β 1-42 (Aβ {42}) and increased tau levels in cerebrospinal fluid (CSF) reflect increased Alzheimer's disease (AD) pathology in the brain. β-site APP cleaving enzyme (BACE1) is thought to be the major β-secretase involved in Aβ production in the brain,

  10. Ad-Hoc Queries over Document Collections - A Case Study

    Science.gov (United States)

    Löser, Alexander; Lutter, Steffen; Düssel, Patrick; Markl, Volker

    We discuss the novel problem of supporting analytical business intelligence queries over web-based textual content, e.g., BI-style reports based on 100.000's of documents from an ad-hoc web search result. Neither conventional search engines nor conventional Business Intelligence and ETL tools address this problem, which lies at the intersection of their capabilities. "Google Squared" or our system GOOLAP.info, are examples of these kinds of systems. They execute information extraction methods over one or several document collections at query time and integrate extracted records into a common view or tabular structure. Frequent extraction and object resolution failures cause incomplete records which could not be joined into a record answering the query. Our focus is the identification of join-reordering heuristics maximizing the size of complete records answering a structured query. With respect to given costs for document extraction we propose two novel join-operations: The multi-way CJ-operator joins records from multiple relationships extracted from a single document. The two-way join-operator DJ ensures data density by removing incomplete records from results. In a preliminary case study we observe that our join-reordering heuristics positively impact result size, record density and lower execution costs.

  11. Study on Sinkhole Attacks in Wireless Ad hoc Networks

    Directory of Open Access Journals (Sweden)

    GAGANDEEP

    2012-06-01

    Full Text Available Wireless ad hoc network is a collection of wireless mobile nodes that dynamically self-organize in arbitrary and temporary network topologies. As compared to conventional network, wireless ad hocnetwork are more vulnerable to the security attacks. The nature and structure of wireless ad hoc network makes it very attractive to attackers, because there is no fixed infrastructure and administrativeapproach in it. “Sinkhole attack” is one of the severe attacks in this type of network; this makes trustable nodes to malicious nodes that result in loss of secure information. This paper focuses on sinkhole attacks on routing protocols such as DSR, AODV. To overcome the problems occur due to sinkhole we discuss about Security-aware routing (SAR which helps to reduce the impact of such attack.

  12. Growth differences of male and female Gottingen minipigs during ad libitum feeding: a pilot study

    DEFF Research Database (Denmark)

    Bollen, P.J.A.; Madsen, L.W.; Meyer, Otto A.

    2005-01-01

    Even though minipigs have been used in biomedical research for nearly half a century now, no specific nutrient requirements are available. For that reason a series of studies into the nutrient requirements of Gottingen minipigs were carried out. Firstly, a pilot study was carried out to determine...... the ad libitum feed intake (FI) during growth, as a reference for later feed restriction studies. Four male and four female minipigs were fed two types of diet, one standard pig diet (20.6% crude protein; 11.7% crude fat; 13.5 mj/kg DM metabolizable energy) and one diet specially designed for minipigs...... backfat thickness. Relative backfat thickness ranged from 5 to 13 cm/100 kg. Females had thicker relative backfat layers than males. Remarkably, no large changes in haematology and clinical chemistry occurred in ad libitum fed Gottingen minipigs as compared to reference values, and no abnormalities other...

  13. A Cluster Maintenance Algorithm Based on Relative Mobility for Mobile Ad Hoc Network Management

    Institute of Scientific and Technical Information of China (English)

    SHENZhong; CHANGYilin; ZHANGXin

    2005-01-01

    The dynamic topology of mobile ad hoc networks makes network management significantly more challenging than wireline networks. The traditional Client/Server (Manager/Agent) management paradigm could not work well in such a dynamic environment, while the hierarchical network management architecture based on clustering is more feasible. Although the movement of nodes makes the cluster structure changeable and introduces new challenges for network management, the mobility is a relative concept. A node with high relative mobility is more prone to unstable behavior than a node with less relative mobility, thus the relative mobility of a node can be used to predict future node behavior. This paper presents the cluster availability which provides a quantitative measurement of cluster stability. Furthermore, a cluster maintenance algorithm based on cluster availability is proposed. The simulation results show that, compared to the Minimum ID clustering algorithm, our algorithm successfully alleviates the influence caused by node mobility and make the network management more efficient.

  14. Giant magnon solution and dispersion relation in string theory in AdS_3 x S^3 x T^4 with mixed flux

    CERN Document Server

    Hoare, B; Tseytlin, A A

    2013-01-01

    We address the question about the exact form of the dispersion relation for light-cone string excitations in string theory in AdS3 x S3 x T4 with mixed R-R and NS-NS 3-form fluxes. The analogy with string theory in AdS5 x S5 suggests that in addition to the data provided by the perturbative near-BMN expansion and the symmetry algebra considerations there is also another source of information about the dispersion relation -- the semiclassical giant magnon solution. In earlier work in arXiv:1303.1037 and arXiv:1304.4099 it was found that the symmetry algebra constraints consistent with perturbative expansion do not completely determine the form of the dispersion relation. The aim of the present paper is to fix it by constructing a generalization of the known dyonic giant magnon soliton on S3 to the presence of a non-zero NS-NS flux described by a WZ term in the string action. We find that the angular momentum of this soliton gets shifted by a term linear in world-sheet momentum. We also discuss the symmetry alg...

  15. Attitudes Towards Ads and Age. A Study in Seniors

    Directory of Open Access Journals (Sweden)

    Marta M. Estrada

    2014-08-01

    Full Text Available Older adults make up one of the markets with the greatest potential in the future. It is essential that businesses take the diversity within this group into account, and perform segmentation in order to obtain a favorable attitude towards the ad. The potential for segmentation by chronological age has been called into question in recent years, with cognitive age emerging as the main alternative. This research aims to analyses the relationship between the variables of attitude towards the ad, attitude towards the brand and purchasing intention among older adults, noting the moderating effect of the joint use of chronological age and cognitive age on these items.  DOI: 10.5585/remark.v13i3.2725

  16. Heavy density liquid metal spallation target studies for Indian ADS programme

    Indian Academy of Sciences (India)

    P Sathamurthy; L M Gantayet; A K Ray

    2007-02-01

    Department of Atomic Energy, India has taken up the development of ADS in view of many attractive features like inherent safety, capability to transmute large quantities of nuclear waste, better utilization of thorium etc. A roadmap has been finalized for the development of ADS. One of the key components of the ADS is the spallation target. Considering the neutron yield, thermal-hydraulics and radiation damage issues, we are proposing to develop spallation target based on heavy density liquid metals like lead and lead-bismuth-eutectic (LBE). Both window and windowless target configurations are presently being studied. In view of the various advantages we are also studying liquid metal flow circulation based on gas lift mechanism. An R&D programme has been initiated to address various physics and technology issues of ADS target. Under this programme, mercury and LBE experimental facilities are presently being set up. Along with these facilities, computational tools related to spallation physics (FLUKA) and CFD are being developed, and the existing ones are utilized to design the entire target loop as well as sub-systems. In this presentation the details of these activities are presented.

  17. Studies on urban vehicular ad-hoc networks

    CERN Document Server

    Zhu, Hongzi

    2013-01-01

    With the advancement of wireless technology, vehicular ad hoc networks (VANETs) are emerging as a promising approach to realizing 'smart cities' and addressing many important transportation problems such as road safety, efficiency, and convenience.This brief provides an introduction to the large trace data set collected from thousands of taxis and buses in Shanghai, the largest metropolis in China. It also presents the challenges, design issues, performance modeling and evaluation of a wide spectrum of VANET research topics, ranging from realistic vehicular mobility models and opportunistic ro

  18. A Provisional Study of ADS Within Turkic Accelerator Complex Project

    CERN Document Server

    Arik, M; Caliskan, A; Cetiner, M A; Sultansoy, S

    2012-01-01

    The Turkic Accelerator Complex (TAC) project has been developed with the support of the Turkish State Planning Organization by the collaboration of 10 Turkish universities. The complex is planned to have four main facilities, namely: SASE FEL Facility Based on 1 GeV Electron Linac, Third Generation Synchrotron Radiation Facility (SR) Based on 3.56 GeV Positron Synchrotron, Super-Charm Factory ($\\sqrt{s} = 3.77$ GeV) by colliding the electron beam coming from the linac with an energy of 1 GeV and positron beam coming through the positron ring with an energy of 3.56 GeV, GeV scale proton accelerator. Later has two-fold goal: Neutron Spallation Source (NSS) and ADS. The proton accelerator construction will have 3 MeV, 100 MeV, and 1 GeV phases. The technical design report is planned to be finished in 2013. Since Turkey has essential Thorium reserves the ADS becomes very attractive for our country as emerging energy technology.

  19. A study on the preparation of value-added products from the nonmetallic minerals

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-12-01

    This report consists of 4 subjects. (1) preparation of value-added products for limestone : The purpose of this study is to develop the process of grade up by economical processes with low and/or middle grade of domestic limestone and of powder coating by dry base. In this year, first of all, we investigated the status of application utilize and related industries with the domestic limestone, and then being consideration with condition selected the adequate sample from Taeback, Uljin, Andong, Jungsun and Kumsan area. (2) development of value added technology of pyrophyllite ore : Considering the value added technology for pyrophyllite ore, the study was carried out for development of manufacturing technology to produce paint's filler from pyrophyllite ore reserved at Bunam mine in Cheongsong, Kyungsangbuk-do. The objective of the study is to develop a technology for not only creating an added value of pyrophyllite but also substituting the imported pyrophyllite product. (3) manufacturing technology of materials for fine chemical and electronic industry use : For use high electrically conductive film and advanced high functional solid lubricant, add new and advanced high functional propertied to fine graphite powder through surface modification with gas and organic materials. In this year, scale up test(30 l/batch) were carried out to stand firm the process of graphite surface control and modification for mass produce and to appraise characteristics of surface modified graphite powders. To arrange in order the test sample for actual apply in related company. (4) manufacturing technology of materials for fine chemical industry use (sericite, muscovite) : During the past three years, we studied on the processing technology and treatment process for recovery of concentrated sericite and muscovite, fine grinding characterization and classification of purified sericite and muscovite and the basic study of surface modification which are used as a source material of

  20. Study of an ADS Loaded with Thorium and Reprocessed Fuel

    Directory of Open Access Journals (Sweden)

    Graiciany de Paula Barros

    2012-01-01

    Full Text Available Accelerator-driven systems (ADSs are investigated for long-lived fission product transmutation and fuel regeneration. The aim of this paper is to investigate the nuclear fuel evolution and the neutronic parameters of a lead-cooled accelerator-driven system used for fuel breeding. The fuel used in some fuel rods was T232hO2 for U233 production. In the other fuel rods was used a mixture based upon Pu-MA, removed from PWR-spent fuel, reprocessed by GANEX, and finally spiked with thorium or depleted uranium. The use of reprocessed fuel ensured the use of T232hO2 without the initial requirement of U233 enrichment. In this paper was used the Monte Carlo code MCNPX 2.6.0 that presents the depletion/burnup capability, combining an ADS source and kcode-mode (for criticality calculations. The multiplication factor (keff evolution, the neutron energy spectra in the core at BOL, and the nuclear fuel evolution during the burnup were evaluated. The results indicated that the combined use of T232hO2 and reprocessed fuel allowed U233 production without the initial requirement of U233 enrichment.

  1. Study Added of Waste Chicken Egg Shell in Soils

    Directory of Open Access Journals (Sweden)

    Keng Wong Irwan Lie

    2016-01-01

    Full Text Available Soil is the foundation of structure or construction that will receive the load transfer through to foundation. If the soil has a carrying capacity of small and cannot withstand the load transfer can result in the failure of construction. If the soil has a carrying capacity of small ground it is necessary to stabilize or improve the soil so that an increase in the carrying capacity of the land so that it can be used for construction. One material is commonly used for soil stabilization with the addition of lime. Waste chicken egg shell is waste that is still rarely used, the results of research [1], states that composition egg shell broadly consists of water (1,6% and dry material (98,4%. The total dry ingredients are there, in shell eggs contained mineral elements (95,1% and protein (3,3%. Based on the existing mineral composition, then the egg shells are composed of crystalline CaCO3 (98,43%, MgCO3 (0,84% and Ca3(PO42 (0,75%. This research was done by adding powdered chicken egg shell waste in clay with a composition of 5%, 7,5%, 10% and 14% with physical properties test and soil compaction test.

  2. Studies on the preparation of value-added products for industrial minerals

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-12-01

    This report consists of 2 subjects. 1) Studies on the preparation of value-added products for limestone: This study has investigated to raise to high grade by economical processes with low grade of domestic limestone. We investigated the status of application utilize and related industries with the domestic limestone, and then being consideration with condition selected the adequate sample from Andong, Jungsun and Kumsan area. Magnetic materials were involved in impurities of sample, so magnetic separation method was applied in elimination of the ferro- and para-magnetic materials, such as chlorite, muscovite, quartz, dolomite, magnetite, feldspar and so on. Investigation of flotation was undertaken to eliminate impurities from limestone crude ore and the tests were performed to get a optimum condition adding oleic acid as a promoter, sodium silicate and sodium carbonate as a conditioning agents and MIBC as a frother, while to float the sulfide minerals added amyl xanthate as a promoter, and sulfuric acid as a pH regulator. Selective crushing and classification methods were performed to eliminate impurities depends on the mineral properties and should be the selective crushing methods are very useful at the manufacturing factory of heavy calcium carbonate with the dry milling system. 2) A study on development of value added technology of pyrophyllite and dickite: Pyrophyllite and dickite have being utilized as refractories, ceramics, cement, fiber glass, paper, rubber, paints etc. However, there are not any domestic companies to produce fillers of pyrophyllite and dickite for plastic and rubber. Moreover, several kinds of fillers are imported every year with expensive price for plastic and rubber filler. This study has purpose to develop manufacturing technologies to produce fillers for plastic and rubber of pyrophyllite and dickite. The chemical and mineralogical properties of samples, the optimum grinding condition and device for producing plastic fillers and

  3. Study on the Current Situation and Evolvement on Ad Hoc Network%Ad Hoc网络的研究现状与发展

    Institute of Scientific and Technical Information of China (English)

    李悦; 蔡振

    2012-01-01

    Ad Hoc networks as a way to temporarily speed automatic network of mobile communication technologyhas been moreattention to the experts, the current wireless Ad Hoc network is a focus of study. This article describes the characteristics of Ad Hoc Networks and applications, and the research situation.%Ad Hoc网络做为一种能够临时快速自动组网的移动通信技术越来越得到专家们的重视,目前Ad Hoc网络也是无线网络研究中的一个重点和热点。介绍了Ad Hoc网络的特点和应用以及Ad Hoc网络的研究状况。

  4. Localization on $AdS_2\\times S^1$

    CERN Document Server

    David, Justin R; Gupta, Rajesh Kumar; Narain, Kumar

    2016-01-01

    Conformal symmetry relates the metric on $AdS_2 \\times S^{1}$ to that of $S^3$. This implies that under a suitable choice of boundary conditions for fields on $AdS_2$ the partition function of conformal field theories on these spaces must agree which makes $AdS_2 \\times S^{1}$ a good testing ground to study localization on non-compact spaces. We study supersymmetry on $AdS_2\\times S^1$ and determine the localizing Lagrangian for ${\\cal N}=2$ supersymmetric Chern-Simons theory on $AdS_2\\times S^1$. We evaluate the partition function of ${\\cal N}=2$ supersymmetric Chern-Simons theory on $AdS_2 \\times S^1$ using localization, where the radius of $S^1$ is $q$ times that of $AdS_2$. With boundary conditions on $AdS_2\\times S^1$ which ensure that all the physical fields are normalizable and lie in the space of square integrable wave functions in $AdS_2$, the result for the partition function precisely agrees with that of the theory on the $q$-fold covering of $S^3$.

  5. Integration and relative value of biomarkers for prediction of MCI to AD progression: Spatial patterns of brain atrophy, cognitive scores, APOE genotype and CSF biomarkers

    Directory of Open Access Journals (Sweden)

    Xiao Da

    2014-01-01

    Full Text Available This study evaluates the individual, as well as relative and joint value of indices obtained from magnetic resonance imaging (MRI patterns of brain atrophy (quantified by the SPARE-AD index, cerebrospinal fluid (CSF biomarkers, APOE genotype, and cognitive performance (ADAS-Cog in progression from mild cognitive impairment (MCI to Alzheimer's disease (AD within a variable follow-up period up to 6 years, using data from the Alzheimer's Disease Neuroimaging Initiative-1 (ADNI-1. SPARE-AD was first established as a highly sensitive and specific MRI-marker of AD vs. cognitively normal (CN subjects (AUC = 0.98. Baseline predictive values of all aforementioned indices were then compared using survival analysis on 381 MCI subjects. SPARE-AD and ADAS-Cog were found to have similar predictive value, and their combination was significantly better than their individual performance. APOE genotype did not significantly improve prediction, although the combination of SPARE-AD, ADAS-Cog and APOE ε4 provided the highest hazard ratio estimates of 17.8 (last vs. first quartile. In a subset of 192 MCI patients who also had CSF biomarkers, the addition of Aβ1–42, t-tau, and p-tau181p to the previous model did not improve predictive value significantly over SPARE-AD and ADAS-Cog combined. Importantly, in amyloid-negative patients with MCI, SPARE-AD had high predictive power of clinical progression. Our findings suggest that SPARE-AD and ADAS-Cog in combination offer the highest predictive power of conversion from MCI to AD, which is improved, albeit not significantly, by APOE genotype. The finding that SPARE-AD in amyloid-negative MCI patients was predictive of clinical progression is not expected under the amyloid hypothesis and merits further investigation.

  6. Integration and relative value of biomarkers for prediction of MCI to AD progression: spatial patterns of brain atrophy, cognitive scores, APOE genotype and CSF biomarkers.

    Science.gov (United States)

    Da, Xiao; Toledo, Jon B; Zee, Jarcy; Wolk, David A; Xie, Sharon X; Ou, Yangming; Shacklett, Amanda; Parmpi, Paraskevi; Shaw, Leslie; Trojanowski, John Q; Davatzikos, Christos

    2014-01-01

    This study evaluates the individual, as well as relative and joint value of indices obtained from magnetic resonance imaging (MRI) patterns of brain atrophy (quantified by the SPARE-AD index), cerebrospinal fluid (CSF) biomarkers, APOE genotype, and cognitive performance (ADAS-Cog) in progression from mild cognitive impairment (MCI) to Alzheimer's disease (AD) within a variable follow-up period up to 6 years, using data from the Alzheimer's Disease Neuroimaging Initiative-1 (ADNI-1). SPARE-AD was first established as a highly sensitive and specific MRI-marker of AD vs. cognitively normal (CN) subjects (AUC = 0.98). Baseline predictive values of all aforementioned indices were then compared using survival analysis on 381 MCI subjects. SPARE-AD and ADAS-Cog were found to have similar predictive value, and their combination was significantly better than their individual performance. APOE genotype did not significantly improve prediction, although the combination of SPARE-AD, ADAS-Cog and APOE ε4 provided the highest hazard ratio estimates of 17.8 (last vs. first quartile). In a subset of 192 MCI patients who also had CSF biomarkers, the addition of Aβ1-42, t-tau, and p-tau181p to the previous model did not improve predictive value significantly over SPARE-AD and ADAS-Cog combined. Importantly, in amyloid-negative patients with MCI, SPARE-AD had high predictive power of clinical progression. Our findings suggest that SPARE-AD and ADAS-Cog in combination offer the highest predictive power of conversion from MCI to AD, which is improved, albeit not significantly, by APOE genotype. The finding that SPARE-AD in amyloid-negative MCI patients was predictive of clinical progression is not expected under the amyloid hypothesis and merits further investigation.

  7. Adding and Subtracting Alternation: Resumption and Prepositional Phrase Chopping in Spanish Relative Clauses

    Science.gov (United States)

    Cerron-Palomino Lopez, Alvaro

    2010-01-01

    This dissertation is a variationist account of two non-standard relative clause (RC) structures in Spanish: resumptive pronouns (RPs) and prepositional-phrase (PP) chopping. Previous typological studies considered RP explanations based on difficulty of processing (Hawkins, 1994), while Spanish-specific quantitative studies proposed a number of…

  8. Bodacious Berry, Potency Wood and the Aging Monster: Gender and Age Relations in Anti-Aging Ads

    Science.gov (United States)

    Calasanti, Toni

    2007-01-01

    This paper situates age discrimination within a broader system of age relations that intersects with other inequalities, and then uses that framework to analyze internet advertisements for the anti-aging industry. Such ads reinforce age and gender relations by positing old people as worthwhile only to the extent that they look and act like those…

  9. Experimental and Theoretical Study of the Rotation of Si Ad-dimers on the Si(100) Surface

    DEFF Research Database (Denmark)

    Swartzentruber, B. S.; Smith, A. P.; Jonsson, Hannes

    1996-01-01

    Scanning tunneling microscopy measurements and first principles density functional theory calculations are used to study the rate of the rotational transition of Si ad-dimers on top of the surface dimer rows of Si(100). The rotation rate and the relative population of the two stable orientations ...... of the ad-dimers are measured as a function of the applied electric field to extract the zero-field behavior. The measured relative stability of the two configurations is used to test the accuracy of various functionals for density functional theory calculations....

  10. A Comparision Study of Common Routing Protocols Used In Wireless Ad-Hoc Networks

    Directory of Open Access Journals (Sweden)

    Basim Alhadidi

    2013-04-01

    Full Text Available The aim of this study is to analyze and compare performance of both reactive and proactive Mobile Ad hoc Networks (MANETs routing protocols using different environments. Wireless networks are divided into two types: infrastructure and ad hoc network. In wireless ad hoc networks each node can be a sender, router and receiver, so these types of network are less structure compared to infrastructure network. Therefore wireless ad hoc networks need special routing protocols to overcome the limitations of wireless ad hoc networks. Wireless ad hoc networks routing protocols can be categorized into two types: reactive (on demand routing protocols and proactive routing protocols. In proactive routing protocols the nodes periodically send control messages across the network to build routing table. Different routing protocols have been simulated using GloMoSim (Global Mobile Information system simulation library and PARSEC compiler. Five multi-hop wireless ad hoc network routing protocols have been simulated to cover a range of design choices: Wireless Routing Protocol (WRP, Fisheye State Routing (FSR, Dynamic Source Routing (DSR, Ad hoc On-demand Distance Vector (AODV and Location Aided Routing (LAR. The protocols are evaluated in different environments to investigate performance metrics. Performance metric includes the following aspects: packets deliver ratio, end-to-end delay and end-to-end throughput.

  11. Value Adding Management

    DEFF Research Database (Denmark)

    Jensen, Per Anker; Katchamart, Akarapong

    2011-01-01

    Purpose: To investigate how Facilities Management (FM) can add value and develop a management concept that can assist facilities managers in implementing value adding strategies and practices. Theory: The study is based on the management model for FM included in the European FM standards, recent...... theories on added value of FM and real estate and the related concept of Value Management from building projects. The study is related to the EuroFM research group on The Added Value of FM. Design/methodology/approach: The study outlines a preliminary theoretical based management concept, which...... is investigated, tested and discussed based on a case study of an international corporation. Findings: The study shows that the management model for FM creates a relevant starting point but also that stakeholder and relationship management is an essential aspect of Value Adding Management. The case study confirms...

  12. Added value of co-morbidity in predicting health-related quality of life in COPD patients.

    NARCIS (Netherlands)

    Manen, J.G. van; Bindels, P.J.E.; Dekker, F.W.; IJzermans, C.J.; Bottema, B.J.A.M.; Zee, J.S. van der; Schadé, E.

    2001-01-01

    The extent to which a chronic obstructive pulmonary disease (COPD) patient is impaired in health-related quality of life (HRQoL) is only to a small extent reflected in clinical and demographical measures. As the influence of comorbidity on HRQoL is less clear, we investigated the added value of 23 c

  13. SIMULATION STUDY OF BLACKHOLE ATTACK IN THE MOBILE AD HOC NETWORKS

    Directory of Open Access Journals (Sweden)

    SHEENU SHARMA

    2009-06-01

    Full Text Available A wireless ad hoc network is a temporary network set up by wireless nodes usually moving randomly and communicating without a network infrastructure. Due to security vulnerabilities of the routing protocols, however, wireless ad hoc networks may be unprotected against attacks by the malicious nodes. In this study we investigated the effects of Blackhole attacks on the network performance. We simulated Blackhole attacks in Qualnet Simulator and measured the packet loss in the network with and without a blackhole. The simulation is done on AODV (Ad hoc On Demand Distance Vector Routing Protocol. The network performance in the presence of a blackhole is reduced up to 26%.

  14. Chasing the effects of Pre-analytical Confounders - a Multicentre Study on CSF-AD biomarkers

    Directory of Open Access Journals (Sweden)

    Maria Joao Leitao

    2015-07-01

    Full Text Available Core cerebrospinal fluid (CSF biomarkers-Aβ42, Tau and pTau–have been recently incorporated in the revised criteria for Alzheimer’s disease (AD. However, their widespread clinical application lacks standardization. Pre-analytical sample handling and storage play an important role in the reliable measurement of these biomarkers across laboratories. In this study, we aim to surpass the efforts from previous studies, by employing a multicentre approach to assess the impact of less studied CSF pre-analytical confounders in AD-biomarkers quantification. Four different centres participated in this study and followed the same established protocol. CSF samples were analysed for three biomarkers (Aβ42, Tau and pTau and tested for different spinning conditions (temperature: Room temperature (RT vs. 4oC; speed: 500g vs. 2000g vs. 3000g, storage volume variations (25%, 50% and 75% of tube total volume as well as freezing-thaw cycles (up to 5 cyles. The influence of sample routine parameters, inter-centre variability and relative value of each biomarker (reported as normal/abnormal, was analysed. Centrifugation conditions did not influence biomarkers levels, except for samples with a high CSF total protein content, where either non centrifugation or centrifugation at RT, compared to 4ºC, led to higher Aβ42 levels. Reducing CSF storage volume from 75% to 50% of total tube capacity, decreased Aβ42 concentration (within analytical CV of the assay, whereas no change in Tau or pTau was observed. Moreover, the concentration of Tau and pTau appears to be stable up to 5 freeze-thaw cycles, whereas Aβ42 levels decrease if CSF is freeze-thawed more than 3 times. This systematic study reinforces the need for CSF centrifugation at 4ºC prior to storage and highlights the influence of storage conditions in Aβ42 levels. This study contributes to the establishment of harmonized standard operating procedures that will help reducing inter-lab variability of CSF-AD

  15. Getting added value from using qualitative research with randomized controlled trials: a qualitative interview study

    OpenAIRE

    2014-01-01

    Background Qualitative research is undertaken with randomized controlled trials of health interventions. Our aim was to explore the perceptions of researchers with experience of this endeavour to understand the added value of qualitative research to the trial in practice. Methods A telephone semi-structured interview study with 18 researchers with experience of undertaking the trial and/or the qualitative research. Results Interviewees described the added value of qualitative research for the...

  16. Dressing phases of AdS3/CFT2

    CERN Document Server

    Borsato, Riccardo; Sfondrini, Alessandro; Stefanski, Bogdan; Torrielli, Alessandro

    2013-01-01

    We determine the all-loop dressing phases of the AdS3/CFT2 integrable system related to type IIB string theory on AdS3 x S3 x T4 by solving the recently found crossing relations and studying their singularity structure. The two resulting phases present a novel structure with respect to the ones appearing in AdS5/CFT4 and AdS4/CFT3. In the strongly-coupled regime, their leading order reduces to the universal Arutyunov-Frolov-Staudacher phase as expected. We also compute their sub-leading order and compare it with recent one-loop perturbative results, and co

  17. Dressing phases of AdS3/CFT2

    Science.gov (United States)

    Borsato, Riccardo; Ohlsson Sax, Olof; Sfondrini, Alessandro; Stefański, Bogdan, Jr.; Torrielli, Alessandro

    2013-09-01

    We determine the all-loop dressing phases of the AdS3/CFT2 integrable system related to type IIB string theory on AdS3×S3×T4 by solving the recently found crossing relations and studying their singularity structure. The two resulting phases present a novel structure with respect to the ones appearing in AdS5/CFT4 and AdS4/CFT3. In the strongly coupled regime, their leading order reduces to the universal Arutyunov-Frolov-Staudacher phase as expected. We also compute their subleading order and compare it with recent one-loop perturbative results and comment on their weak-coupling expansion.

  18. Mobile Codes Localization in Ad hoc Networks: a Comparative Study of Centralized and Distributed Approaches

    CERN Document Server

    Zafoune, Youcef; kanawati, Rushed; 10.5121/ijcnc.2010.2213

    2010-01-01

    This paper presents a new approach in the management of mobile ad hoc networks. Our alternative, based on mobile agent technology, allows the design of mobile centralized server in ad hoc network, where it is not obvious to think about a centralized management, due to the absence of any administration or fixed infrastructure in these networks. The aim of this centralized approach is to provide permanent availability of services in ad hoc networks which are characterized by a distributed management. In order to evaluate the performance of the proposed approach, we apply it to solve the problem of mobile code localization in ad hoc networks. A comparative study, based upon a simulation, of centralized and distributed localization protocols in terms of messages number exchanged and response time shows that the centralized approach in a distributed form is more interesting than a totally centralized approach.

  19. Chasing the Effects of Pre-Analytical Confounders - A Multicenter Study on CSF-AD Biomarkers

    DEFF Research Database (Denmark)

    Leitão, Maria João; Baldeiras, Inês; Herukka, Sanna-Kaisa

    2015-01-01

    play an important role in the reliable measurement of these biomarkers across laboratories. AIM: In this study, we aim to surpass the efforts from previous studies, by employing a multicenter approach to assess the impact of less studied CSF pre-analytical confounders in AD-biomarkers quantification...

  20. A high performance, ad-hoc, fuzzy query processing system for relational databases

    Science.gov (United States)

    Mansfield, William H., Jr.; Fleischman, Robert M.

    1992-01-01

    Database queries involving imprecise or fuzzy predicates are currently an evolving area of academic and industrial research. Such queries place severe stress on the indexing and I/O subsystems of conventional database environments since they involve the search of large numbers of records. The Datacycle architecture and research prototype is a database environment that uses filtering technology to perform an efficient, exhaustive search of an entire database. It has recently been modified to include fuzzy predicates in its query processing. The approach obviates the need for complex index structures, provides unlimited query throughput, permits the use of ad-hoc fuzzy membership functions, and provides a deterministic response time largely independent of query complexity and load. This paper describes the Datacycle prototype implementation of fuzzy queries and some recent performance results.

  1. Age-related intraneuronal elevation of αII-spectrin breakdown product SBDP120 in rodent forebrain accelerates in 3×Tg-AD mice.

    Directory of Open Access Journals (Sweden)

    Yan Cai

    Full Text Available Spectrins line the intracellular surface of plasmalemma and play a critical role in supporting cytoskeletal stability and flexibility. Spectrins can be proteolytically degraded by calpains and caspases, yielding breakdown products (SBDPs of various molecular sizes, with SBDP120 being largely derived from caspase-3 cleavage. SBDPs are putative biomarkers for traumatic brain injury. The levels of SBDPs also elevate in the brain during aging and perhaps in Alzheimer's disease (AD, although the cellular basis for this change is currently unclear. Here we examined age-related SBDP120 alteration in forebrain neurons in rats and in the triple transgenic model of AD (3×Tg-AD relative to non-transgenic controls. SBDP120 immunoreactivity (IR was found in cortical neuronal somata in aged rats, and was prominent in the proximal dendrites of the olfactory bulb mitral cells. Western blot and densitometric analyses in wild-type mice revealed an age-related elevation of intraneuronal SBDP120 in the forebrain which was more robust in their 3×Tg-AD counterparts. The intraneuronal SBDP120 occurrence was not spatiotemporally correlated with transgenic amyloid precursor protein (APP expression, β-amyloid plaque development, or phosphorylated tau expression over various forebrain regions or lamina. No microscopically detectable in situ activated caspase-3 was found in the nuclei of SBDP120-containing neurons. The present study demonstrates the age-dependent intraneuronal presence of an αII-spectrin cleavage fragment in mammalian forebrain which is exacerbated in a transgenic model of AD. This novel neuronal alteration indicates that impairments in membrane protein metabolism, possibly due to neuronal calcium mishandling and/or enhancement of calcium sensitive proteolysis, occur during aging and in transgenic AD mice.

  2. Age-related intraneuronal elevation of αII-spectrin breakdown product SBDP120 in rodent forebrain accelerates in 3×Tg-AD mice.

    Science.gov (United States)

    Cai, Yan; Zhu, Hai-Xia; Li, Jian-Ming; Luo, Xue-Gang; Patrylo, Peter R; Rose, Gregory M; Streeter, Jackson; Hayes, Ron; Wang, Kevin K W; Yan, Xiao-Xin; Jeromin, Andreas

    2012-01-01

    Spectrins line the intracellular surface of plasmalemma and play a critical role in supporting cytoskeletal stability and flexibility. Spectrins can be proteolytically degraded by calpains and caspases, yielding breakdown products (SBDPs) of various molecular sizes, with SBDP120 being largely derived from caspase-3 cleavage. SBDPs are putative biomarkers for traumatic brain injury. The levels of SBDPs also elevate in the brain during aging and perhaps in Alzheimer's disease (AD), although the cellular basis for this change is currently unclear. Here we examined age-related SBDP120 alteration in forebrain neurons in rats and in the triple transgenic model of AD (3×Tg-AD) relative to non-transgenic controls. SBDP120 immunoreactivity (IR) was found in cortical neuronal somata in aged rats, and was prominent in the proximal dendrites of the olfactory bulb mitral cells. Western blot and densitometric analyses in wild-type mice revealed an age-related elevation of intraneuronal SBDP120 in the forebrain which was more robust in their 3×Tg-AD counterparts. The intraneuronal SBDP120 occurrence was not spatiotemporally correlated with transgenic amyloid precursor protein (APP) expression, β-amyloid plaque development, or phosphorylated tau expression over various forebrain regions or lamina. No microscopically detectable in situ activated caspase-3 was found in the nuclei of SBDP120-containing neurons. The present study demonstrates the age-dependent intraneuronal presence of an αII-spectrin cleavage fragment in mammalian forebrain which is exacerbated in a transgenic model of AD. This novel neuronal alteration indicates that impairments in membrane protein metabolism, possibly due to neuronal calcium mishandling and/or enhancement of calcium sensitive proteolysis, occur during aging and in transgenic AD mice.

  3. Studies on the preparation of value-added products for limestone

    Energy Technology Data Exchange (ETDEWEB)

    Chae, Young Bae; Jeong, Soo Bok; Ko, Won Sik; Park, Je Shin; Oh, Jung Whan [Korea Institute of Geology Mining and Materials, Taejon (Korea, Republic of)

    1997-12-01

    Most of limestone in our country was consumed by the cement and iron/steel making industries and the amount of that was up to 72 million ton in 1996. Recently, importation of high grade limestone that have properties of high whiteness and grade are increased with diversification of chemical products and powder as various qualified filler, because high grade limestone are limited and of few deposit in our country. Therefore, the purpose of this study has investigated to raise to high grade by economical processes with low grade of domestic limestone. In this year, first of all, we investigated the status of application utilize and related industries with the domestic limestone, and then being consideration with condition selected the adequate sample from Andong, Jungsun and Kumsan area. Magnetic materials were involved in impurities of sample, so magnetic separation method was applied in elimination of the ferro-magnetic materials and para-magnetic materials, such as chlorite, muscovite, quartz, dolomite, magnetite, feldspar and so on. The limestone sample has many kinds of impurity. Investigation of flotation was undertaken to eliminate impurities from limestone crude ore and the tests were performed to get a optimum condition adding oleic acid as a promoter, sodium silicate and sodium carbonate as a conditioning agents and MIBC as a frother, while to float the sulfide minerals added amyl xanthate as a promoter, and sulfuric acid as a pH regulator. And most of the impurities involving in flotation sink contained such as quartz, chlorite, muscovite, feldspar, dolomite and so on. Selective crushing and classification methods were performed to eliminate impurities depends on the mineral properties and should be the selective crushing methods are very useful at the manufacturing factory of heavy calcium carbonate with the dry milling system. (author). 36 refs., 46 tabs., 33 figs.

  4. A Value-Added Study of Teacher Spillover Effects across Four Core Subjects in Middle Schools

    Science.gov (United States)

    Yuan, Kun

    2015-01-01

    This study examined the existence, magnitude, and impact of teacher spillover effects (TSEs) across teachers of four subject areas (i.e., mathematics, English language arts [ELA], science, and social studies) on student achievement in each of the four subjects at the middle school level. The author conducted a series of value-added (VA) analyses,…

  5. Association between alcohol consumption and diabetic retinopathy and visual acuity-the AdRem Study

    NARCIS (Netherlands)

    Lee, C. C.; Stolk, R. P.; Adler, A. I.; Patel, A.; Chalmers, J.; Neal, B.; Poulter, N.; Harrap, S.; Woodward, M.; Marre, M.; Grobbee, D. E.; Beulens, J. W.

    2010-01-01

    Aims We investigated the association between alcohol consumption and diabetic retinopathy and deterioration of visual acuity in individuals with Type 2 diabetes. Methods We conducted a cohort analysis of 1239 participants with Type 2 diabetes aged 55-81 years enrolled in the AdRem study, a sub-study

  6. The added value of water footprint assessment for national water policy: a case study for Morocco.

    Directory of Open Access Journals (Sweden)

    Joep F Schyns

    Full Text Available A Water Footprint Assessment is carried out for Morocco, mapping the water footprint of different activities at river basin and monthly scale, distinguishing between surface- and groundwater. The paper aims to demonstrate the added value of detailed analysis of the human water footprint within a country and thorough assessment of the virtual water flows leaving and entering a country for formulating national water policy. Green, blue and grey water footprint estimates and virtual water flows are mainly derived from a previous grid-based (5 × 5 arc minute global study for the period 1996-2005. These estimates are placed in the context of monthly natural runoff and waste assimilation capacity per river basin derived from Moroccan data sources. The study finds that: (i evaporation from storage reservoirs is the second largest form of blue water consumption in Morocco, after irrigated crop production; (ii Morocco's water and land resources are mainly used to produce relatively low-value (in US$/m3 and US$/ha crops such as cereals, olives and almonds; (iii most of the virtual water export from Morocco relates to the export of products with a relatively low economic water productivity (in US$/m3; (iv blue water scarcity on a monthly scale is severe in all river basins and pressure on groundwater resources by abstractions and nitrate pollution is considerable in most basins; (v the estimated potential water savings by partial relocation of crops to basins where they consume less water and by reducing water footprints of crops down to benchmark levels are significant compared to demand reducing and supply increasing measures considered in Morocco's national water strategy.

  7. The added value of water footprint assessment for national water policy: a case study for Morocco.

    Science.gov (United States)

    Schyns, Joep F; Hoekstra, Arjen Y

    2014-01-01

    A Water Footprint Assessment is carried out for Morocco, mapping the water footprint of different activities at river basin and monthly scale, distinguishing between surface- and groundwater. The paper aims to demonstrate the added value of detailed analysis of the human water footprint within a country and thorough assessment of the virtual water flows leaving and entering a country for formulating national water policy. Green, blue and grey water footprint estimates and virtual water flows are mainly derived from a previous grid-based (5 × 5 arc minute) global study for the period 1996-2005. These estimates are placed in the context of monthly natural runoff and waste assimilation capacity per river basin derived from Moroccan data sources. The study finds that: (i) evaporation from storage reservoirs is the second largest form of blue water consumption in Morocco, after irrigated crop production; (ii) Morocco's water and land resources are mainly used to produce relatively low-value (in US$/m3 and US$/ha) crops such as cereals, olives and almonds; (iii) most of the virtual water export from Morocco relates to the export of products with a relatively low economic water productivity (in US$/m3); (iv) blue water scarcity on a monthly scale is severe in all river basins and pressure on groundwater resources by abstractions and nitrate pollution is considerable in most basins; (v) the estimated potential water savings by partial relocation of crops to basins where they consume less water and by reducing water footprints of crops down to benchmark levels are significant compared to demand reducing and supply increasing measures considered in Morocco's national water strategy.

  8. Comparative study of Attacks on AODV-based Mobile Ad Hoc Networks

    Directory of Open Access Journals (Sweden)

    Ipsa De

    2011-01-01

    Full Text Available In recent years, the use of mobile ad hoc networks (MANETs has been widespread in many applications, The lack of infrastructures in MANETs makes the detection and control of security hazards allthe more difficult. The security issue is becoming a major concern and bottle neck in the application of MANET. In this paper, an attempt has been made to thoroughly study the blackhole attack which is one ofthe possible attacks in ad hoc networks in routing protocol AODV with possible solution to blackhole attack detection.

  9. Adding Hierarchical Objects to Relational Database General-Purpose XML-Based Information Managements

    Science.gov (United States)

    Lin, Shu-Chun; Knight, Chris; La, Tracy; Maluf, David; Bell, David; Tran, Khai Peter; Gawdiak, Yuri

    2006-01-01

    NETMARK is a flexible, high-throughput software system for managing, storing, and rapid searching of unstructured and semi-structured documents. NETMARK transforms such documents from their original highly complex, constantly changing, heterogeneous data formats into well-structured, common data formats in using Hypertext Markup Language (HTML) and/or Extensible Markup Language (XML). The software implements an object-relational database system that combines the best practices of the relational model utilizing Structured Query Language (SQL) with those of the object-oriented, semantic database model for creating complex data. In particular, NETMARK takes advantage of the Oracle 8i object-relational database model using physical-address data types for very efficient keyword searches of records across both context and content. NETMARK also supports multiple international standards such as WEBDAV for drag-and-drop file management and SOAP for integrated information management using Web services. The document-organization and -searching capabilities afforded by NETMARK are likely to make this software attractive for use in disciplines as diverse as science, auditing, and law enforcement.

  10. Cardiovascular disease prediction: do pulmonary disease-related chest CT features have added value?

    Energy Technology Data Exchange (ETDEWEB)

    Jairam, Pushpa M. [University Medical Center Utrecht, Julius Center for Health Sciences and Primary Care, Utrecht (Netherlands); University Medical Center Utrecht, Department of Radiology, Utrecht (Netherlands); Jong, Pim A. de; Mali, Willem P.T.M. [University Medical Center Utrecht, Department of Radiology, Utrecht (Netherlands); Isgum, Ivana [University Medical Center Utrecht, Image Sciences Institute, Utrecht (Netherlands); Graaf, Yolanda van der [University Medical Center Utrecht, Julius Center for Health Sciences and Primary Care, Utrecht (Netherlands); Collaboration: PROVIDI study-group

    2015-06-01

    Certain pulmonary diseases are associated with cardiovascular disease (CVD). Therefore we investigated the incremental predictive value of pulmonary, mediastinal and pleural features over cardiovascular imaging findings. A total of 10,410 patients underwent diagnostic chest CT for non-cardiovascular indications. Using a case-cohort approach, we visually graded CTs from the cases and from an approximately 10 % random sample of the baseline cohort (n = 1,203) for cardiovascular, pulmonary, mediastinal and pleural findings. The incremental value of pulmonary disease-related CT findings above cardiovascular imaging findings in cardiovascular event risk prediction was quantified by comparing discrimination and reclassification. During a mean follow-up of 3.7 years (max. 7.0 years), 1,148 CVD events (cases) were identified. Addition of pulmonary, mediastinal and pleural features to a cardiovascular imaging findings-based prediction model led to marginal improvement of discrimination (increase in c-index from 0.72 (95 % CI 0.71-0.74) to 0.74 (95 % CI 0.72-0.75)) and reclassification measures (net reclassification index 6.5 % (p < 0.01)). Pulmonary, mediastinal and pleural features have limited predictive value in the identification of subjects at high risk of CVD events beyond cardiovascular findings on diagnostic chest CT scans. (orig.)

  11. Study of micro piezoelectric vibration generator with added mass and capacitance suitable for broadband vibration

    Directory of Open Access Journals (Sweden)

    Qing He

    2015-07-01

    Full Text Available This study proposes an optimized frequency adjustment method that uses a micro-cantilever beam-based piezoelectric vibration generator based on a combination of added mass and capacitance. The most important concept of the proposed method is that the frequency adjustment process is divided into two steps: the first is a rough adjustment step that changes the size of the mass added at the end of cantilever to adjust the frequency in a large-scale and discontinuous manner; the second step is a continuous but short-range frequency adjustment via the adjustable added capacitance. Experimental results show that when the initial natural frequency of a micro piezoelectric vibration generator is 69.8 Hz, then this natural frequency can be adjusted to any value in the range from 54.2 Hz to 42.1 Hz using the combination of the added mass and the capacitance. This method simply and effectively matches a piezoelectric vibration generator’s natural frequency to the vibration source frequency.

  12. Study of micro piezoelectric vibration generator with added mass and capacitance suitable for broadband vibration

    Energy Technology Data Exchange (ETDEWEB)

    He, Qing, E-mail: hqng@163.com; Mao, Xinhua, E-mail: 30400414@qq.com; Chu, Dongliang, E-mail: 569256386@qq.com [School of Energy, Power and Mechanical Engineering, North China Electric Power University, Beijing 102206 (China)

    2015-07-15

    This study proposes an optimized frequency adjustment method that uses a micro-cantilever beam-based piezoelectric vibration generator based on a combination of added mass and capacitance. The most important concept of the proposed method is that the frequency adjustment process is divided into two steps: the first is a rough adjustment step that changes the size of the mass added at the end of cantilever to adjust the frequency in a large-scale and discontinuous manner; the second step is a continuous but short-range frequency adjustment via the adjustable added capacitance. Experimental results show that when the initial natural frequency of a micro piezoelectric vibration generator is 69.8 Hz, then this natural frequency can be adjusted to any value in the range from 54.2 Hz to 42.1 Hz using the combination of the added mass and the capacitance. This method simply and effectively matches a piezoelectric vibration generator’s natural frequency to the vibration source frequency.

  13. Utility of AD8 for Cognitive Impairment in a Chinese Physical Examination Population: A Preliminary Study

    Directory of Open Access Journals (Sweden)

    Yue Xie

    2014-01-01

    Full Text Available Objective. To investigate the utility of AD8 for cognitive impairment in a Chinese physical examination population. Methods. Military cadres who took routine physical examination in Chinese PLA General Hospital from Jan 1, 2013, to Dec 31, 2013, were subjected to AD8 scale. Individual information such as age, gender, and education was also collected. All data were analyzed by SPSS 19.0. Results. 1544 subjects were enrolled in this study with mean age 75.4 ± 10.6 years. The subjects who scored 0 to 8 of AD8 scale were 1015, 269, 120, 60, 30, 14, 19, 8, and 9, respectively. Corresponding proportions were 65.7%, 17.4%, 7.8%, 3.9%, 2.0%, 0.9%, 1.2%, 0.5%, and 0.6%, respectively. The endorsement prevalence of 8 questions was 5.6%, 9.2%, 6.6%, 9.2%, 4.8%, 4.5%, 8.9%, and 24.1%, respectively. The endorsement prevalence of question 8 was significantly higher than others (P<0.05. 260 subjects were scored equal to or greater than 2. The abnormal rate was 16.9%. All the participants were stratified into 9 groups by age; the prevalence of dementia was highly correlated with age (P<0.01. Conclusion. AD8 scale is a convenient and effective tool for cognitive screening in routine physical examination population.

  14. Species dependent studies of no-carrier-added {sup 93m}Mo: A green method

    Energy Technology Data Exchange (ETDEWEB)

    Mandal, Swadesh, E-mail: swadeshchem@rediffmail.co [Chemical Sciences Division, Saha Institute of Nuclear Physics, 1/AF Bidhannagar, Kolkata 700064 (India); Nayak, Dalia [Chemical Sciences Division, Saha Institute of Nuclear Physics, 1/AF Bidhannagar, Kolkata 700064 (India)

    2010-10-15

    The present paper reports a combination of radioanalytical and green methodology for the ultra-trace scale speciation of molybdenum. The differential attitude of iron-doped calcium alginate (Fe-CA) and chitosan biopolymers towards no-carrier-added {sup 93m}Mo radionuclide was studied to develop environmentally sustainable speciation methodology in ultra-trace scale. The affinity of {sup 93m}Mo towards the Fe-CA beads is greater than that of chitosan. Species information was obtained by comparing the adsorption profile of {sup 93m}Mo on Fe-CA and chitosan biopolymer with the software code CHEAQS PRO program. From the experimental results it is concluded that no-carrier-added {sup 93m}Mo radionuclide form mononuclear species instead of polynuclear species in aqueous solution. Use of biodegradable, non-toxic biopolymer makes this method a step forward towards green chemistry.

  15. Effect of Added Brine on the Physico Chemical Studies of Sodium Dodecyl Sulfate and Aqueous Gelatin

    Science.gov (United States)

    George, Jinu; Sreejith, Lisa

    2011-10-01

    Effect of added brine on the structural transitions of SDS, in different compositions of gelatin has been investigated by viscosity, circular dichroism, TGA and DSC. The slow and steady growth of the normal spherical micelles to the higher order aggregates were predicted by viscosity and conductivity measurements. The large negative value for ellipticity observed from CD measurements indicated absence of any conformational change for gelatin. Other measurements were used to study the molecular packing in the micellar aggregates. The complex formed exhibits fantastic properties to be explored in the field of smart gels.

  16. Studies on the preparation of value-added products for limestone

    Energy Technology Data Exchange (ETDEWEB)

    Chae, Young Bae; Jeong, Soo Bok; Ko, Won Sik; Chang, Byung Pyo [Korea Institute of Geology Mining and Materials, Taejon (Korea)

    1998-12-01

    Imports of high grade limestone and calcium carbonate powder that have properties of high whiteness and grade are increased with diversification of chemical products and powder as various qualified filler, because high grade limestone are limited or few deposited in our country. There are three kinds in the importation calcium carbonate powder that have properties of high whiteness over 95 deg., high purity and hydrophobic with fatty acid coating at the powder surface. This study is to develop the process of grade up by economical processes with low and/or middle grade of domestic limestone and of powder coating by dry base. We investigated the status of application utilize and related industries with the domestic limestone, and then being consideration with condition selected the adequate sample from Taeback, Uljin, Andong, Jungsun and Kumsan area. The limestone sample has many kinds of impurity. So, the method of preparation used in this experiment is Magnetic separation, Flotation, Selective crushing and Precision Classifying according the mineral properties. Magnetic separation method was applied in elimination of the ferro-magnetic materials and para-magnetic materials, such as chlorite, muscovite, quartz dolomite, magnetite, feldspar and so on. Flotation process was undertaken to eliminate of the small size impurities form limestone crude ore and the tests were performed to get a optimum condition adding oleic acid as a promoter, sodium silicate and sodium carbonate as a conditioning agents and MIBC as a frother and sulfuric acid as a pH regulator. Selective crushing and classification methods were performed for eliminated impurities depends on the mineral properties and should be the selective crushing methods on the mineral properties and should be the selective crushing methods are very useful at the manufacturing process of heavy calcium carbonate with the dry milling system. In the heavy calcium carbonate powder coating experiments, A contact angle of

  17. How One School Implements and Experiences Ohio's Value-Added Model: A Case Study

    Science.gov (United States)

    Quattrochi, David

    2009-01-01

    Ohio made value-added law in 2003 and incorporated value-added assessment to its operating standards for teachers and administrators in 2006. Value-added data is used to determine if students are making a year's growth at the end of each school year. Schools and districts receive a rating of "Below Growth, Met Growth, or Above Growth" on…

  18. Polarised black holes in AdS

    Science.gov (United States)

    Costa, Miguel S.; Greenspan, Lauren; Oliveira, Miguel; Penedones, João; Santos, Jorge E.

    2016-06-01

    We consider solutions in Einstein-Maxwell theory with a negative cosmological constant that asymptote to global AdS 4 with conformal boundary {S}2× {{{R}}}t. At the sphere at infinity we turn on a space-dependent electrostatic potential, which does not destroy the asymptotic AdS behaviour. For simplicity we focus on the case of a dipolar electrostatic potential. We find two new geometries: (i) an AdS soliton that includes the full backreaction of the electric field on the AdS geometry; (ii) a polarised neutral black hole that is deformed by the electric field, accumulating opposite charges in each hemisphere. For both geometries we study boundary data such as the charge density and the stress tensor. For the black hole we also study the horizon charge density and area, and further verify a Smarr formula. Then we consider this system at finite temperature and compute the Gibbs free energy for both AdS soliton and black hole phases. The corresponding phase diagram generalizes the Hawking-Page phase transition. The AdS soliton dominates the low temperature phase and the black hole the high temperature phase, with a critical temperature that decreases as the external electric field increases. Finally, we consider the simple case of a free charged scalar field on {S}2× {{{R}}}t with conformal coupling. For a field in the SU(N ) adjoint representation we compare the phase diagram with the above gravitational system.

  19. Segmented Strings in $AdS_3$

    CERN Document Server

    Callebaut, Nele; Samberg, Andreas; Toldo, Chiara

    2015-01-01

    We study segmented strings in flat space and in $AdS_3$. In flat space, these well known classical motions describe strings which at any instant of time are piecewise linear. In $AdS_3$, the worldsheet is composed of faces each of which is a region bounded by null geodesics in an $AdS_2$ subspace of $AdS_3$. The time evolution can be described by specifying the null geodesic motion of kinks in the string at which two segments are joined. The outcome of collisions of kinks on the worldsheet can be worked out essentially using considerations of causality. We study several examples of closed segmented strings in $AdS_3$ and find an unexpected quasi-periodic behavior. We also work out a WKB analysis of quantum states of yo-yo strings in $AdS_3$ and find a logarithmic term reminiscent of the logarithmic twist of string states on the leading Regge trajectory.

  20. Risk Analyses and Studies on ADS-B System%ADS-B系统的原理分析与风险研究

    Institute of Scientific and Technical Information of China (English)

    胡飞

    2011-01-01

    ADS-B技术是下一代空中交通管制技术的重要组成部分,与传统雷达技术相比,它具有可靠性高、成本低等优点.本文简要介绍了ADS-B的基本概念,并以基于UAT数据链的ADS-B系统为例,对ADS-B系统的原理进行了分析.同时,指出了ADS-B系统运行过程中存在的系统风险.

  1. The role of starch and saliva in tribology studies and the sensory perception of protein-added yogurts.

    Science.gov (United States)

    Morell, Pere; Chen, Jianshe; Fiszman, Susana

    2017-02-22

    Increasing the protein content of yogurts would be a good strategy for enhancing their satiating ability. However, the addition of protein can affect product palatability, contributing astringency or an inhomogeneous texture. Increasingly, studies mimicking oral tribology and oral lubrication have been attracting interest among food researchers because of their link with oral texture sensations. In the present study, four double-protein stirred yogurts were prepared by adding extra skimmed milk powder (MP) or whey protein concentrate (WPC) and by adding a physically modified starch to each (samples MPS and WPCS, respectively) to increase the consistency of the yogurts. The lubricating properties of the four yogurts were examined by tribological methods with the aim of relating these properties to the sensory perception described by flash profiling. Samples were also analysed after mixing with saliva. The tribology results clearly showed that addition of starch reduced the friction coefficient values regardless of the type of protein. Saliva addition produced a further decrease in the friction coefficient values in all the samples. Consequently, adding saliva is recommended when performing tribology measurements of foods in order to give a more realistic picture. The sensory results confirmed that the addition of starch reduced the astringent sensation, especially in sample WPC, while the MP and MPS samples were creamier and smoother. On the other hand, the astringency of sample WPC was not explained by the tribology results. Since this sample was described as "grainy", "gritty", "rough", "acid" and "sour", further studies are necessary to investigate the role of the number, size, shape and distribution of particles in yogurt samples, their role in astringency perception and their interaction with the perception of the tastes mentioned. Oral tribology has shown itself to be an in vitro technique that may aid a better understanding of the dynamics of in

  2. Dilatometric studies of Y2W3O12 with added Al2O3

    Indian Academy of Sciences (India)

    S Sumithra; A M Umarji

    2003-10-01

    Y2W3O12 exhibits negative thermal expansion along the three crystallographic directions due to the transverse thermal vibrations perpendicular to the Y-O-W linkage. It is highly hygroscopic and forms a trihydrate structure at room temperature. Dilatometric studies of Y2W3O12 show large thermal expansion hysteresis due to large grain size and a large initial positive thermal expansion due to the removal of water molecules. Al2O3 has been added to Y2W3O12 up to 10 wt% in an attempt to overcome the hygroscopicity and reduce the particle size and thereby the thermal expansion hysteresis. Thermo gravimetric, dilatometric and electron microscopic studies are presented to support these observations.

  3. The 365 AD tsunami imprint on the coasts of southwestern Crete - Sougia and Palaiochora case studies

    Science.gov (United States)

    Werner, Vera; Baika, Kalliopi; Tzigounaki, Anastasia; Tsigkou, Aggeliki; Fischer, Peter; Reicherter, Klaus; Papanikolaou, Ioannis; Vött, Andreas

    2016-04-01

    The southwestern coast of Crete, one of the most seismically active regions in Europe, is supposed to have been uplifted by up to 9 m during the mega-earthquake that struck the eastern Mediterranean world on July 21, 365 AD. An associated tsunami event is known to have caused thousands of fatalities and destroyed many coastal settlements and infrastructure between the Levante in the east and the Adriatic Sea in the northwest. Since this event, the entire southwestern coast of Crete has experienced strong erosion so that near-coast geological archives showing relevant Holocene sedimentary records are rare. So far, distinct palaeotsunami fingerprints from coastal archives in this region were unknown. A multi-proxy study including sedimentological, geochemical, geochronological and microfaunal methods was conducted at Sougia, within an ancient harbour basin, and around the promontory of Palaiochora. Detailed multi-electrode geoelectrical studies and several near-coast vibracores helped to detect promising local sedimentary archives. In addition, prominent elevated shorelines, evidenced by notches and algal rims, were measured with DGPS. Sedimentary archives found at Sougia and Palaiochora revealed distinct sedimentological, geochemical and geomorphological traces of high-energy inundation from the marine side. At Sougia, we found a sheet of allochthonous marine sand, partly cemented, intersecting silt-dominated harbour deposits. At Palaiochora, we found high-energy channels eroded in the local bedrock and filled with marine-borne sand and gravel on top of the Palaiochora isthmus, today some 400 m inland. Based on geochemical and microfaunal fingerprints and on sedimentary features, high-energy deposits are interpreted as tsunamites. 14C-AMS- and OSL dating approaches revealed that the tsunami sequences from both Sougia and Palaiochora were deposited during the 365 AD tsunami event. We also present and discuss conceptual tsunami landfall scenarios for both study sites.

  4. Study on CO{sub 2} absorption enhancement by adding active carbon particles into MEA solution

    Energy Technology Data Exchange (ETDEWEB)

    Qian, Juan; Sun, Rui; Ma, Lian; Sun, Shaozeng [Harbin Institute of Technology, Harbin (China). School of Energy Science and Engineering

    2013-07-01

    The chemical absorption of CO{sub 2} is generally recognized as the most efficient post-combustion technology of CO{sub 2} separation at present. A study on CO{sub 2} absorption enhancement by adding small particles of active carbon into MEA solution is investigated within a self-designed glass stirring tank. Experiments of different particle loadings and different particle sizes have been conducted. When active carbon particle concentration is fewer, compared to the absorption rate of CO{sub 2} gas absorbed by MEA aqueous solution, the role of active carbon adsorption CO{sub 2} gas is negligible. The enhancement efficiency of CO{sub 2} absorption could be improved by 10% to the upmost in this liquid-particle system.

  5. Brain glucose metabolism in the early and specific diagnosis of Alzheimer's disease. FDG-PET studies in MCI and AD

    Energy Technology Data Exchange (ETDEWEB)

    Mosconi, Lisa [University of Florence, Department of Clinical Pathophysiology, Nuclear Medicine Unit (Italy); University School of Medicine, Center for Brain Health, MHL400, Department of Psychiatry New York, New York, NY (United States)

    2005-04-01

    The demographics of aging suggest a great need for the early diagnosis of dementia and the development of preventive strategies. Neuropathology and structural MRI studies have pointed to the medial temporal lobe (MTL) as the brain region earliest affected in Alzheimer's disease (AD). MRI findings provide strong evidence that in mild cognitive impairments (MCI), AD-related volume losses can be reproducibly detected in the hippocampus, the entorhinal cortex (EC) and, to a lesser extent, the parahippocampal gyrus; they also indicate that lateral temporal lobe changes are becoming increasingly useful in predicting the transition to dementia. Fluoro-2-deoxy-D-glucose positron emission tomography (FDG-PET) imaging has revealed glucose metabolic reductions in the parieto-temporal, frontal and posterior cingulate cortices to be the hallmark of AD. Overall, the pattern of cortical metabolic changes has been useful for the prediction of future AD as well as in distinguishing AD from other neurodegenerative diseases. FDG-PET on average achieves 90% sensitivity in identifying AD, although specificity in differentiating AD from other dementias is lower. Moreover, recent MRI-guided FDG-PET studies have shown that MTL hypometabolism is the most specific and sensitive measure for the identification of MCI, while the utility of cortical deficits is controversial. This review highlights cross-sectional, prediction and longitudinal FDG-PET studies and attempts to put into perspective the value of FDG-PET in diagnosing AD-like changes, particularly at an early stage, and in providing diagnostic specificity. The examination of MTL structures, which has so far been exclusive to MRI protocols, is then examined as a possible strategy to improve diagnostic specificity. All told, there is considerable promise that early and specific diagnosis is feasible through a combination of imaging modalities. (orig.)

  6. A Study of Mobile Ad Hoc Network Management Architecture%移动Ad hoc网络管理架构研究

    Institute of Scientific and Technical Information of China (English)

    耿哲; 徐晓宇

    2005-01-01

    在介绍移动Ad hoc网络特定管理要求的基础上,分析了SNMP/ANMP、Guerrilla和PBNM三种Ad hoc网络管理架构的机制和特点.研究表明管理框架应适应Ad hoc网络动态拓扑、带宽受限和节点能力有限等特点,而分布式、自适应和智能化的网络管理是未来Ad hoc网络管理发展的方向.

  7. Value-Added Dairy Products from Grass-Based Dairy Farms: A Case Study in Vermont

    Science.gov (United States)

    Wang, Qingbin; Parsons, Robert; Colby, Jennifer; Castle, Jeffrey

    2016-01-01

    On-farm processing of value-added dairy products can be a way for small dairy farms to diversify production and increase revenue. This article examines characteristics of three groups of Vermont farmers who have grass-based dairy farms--those producing value-added dairy products, those interested in such products, and those not interested in such…

  8. Old Words, New Meanings: A Study of Trends in Science Librarian Job Ads

    Science.gov (United States)

    Bychowski, Brenna K. H.; Caffrey, Carolyn M.; Costa, Mia C.; Moore, Angela D.; Sudhakaran, Jessamyn; Zhang, Yuening

    2010-01-01

    Job ads are supposed to provide careful descriptions of the positions being advertised. Based on this premise, an analysis of job ads over time should reveal emerging trends and changes in a profession. The existing literature on science librarianship emphasizes that there are fluctuations in the demand for subject expertise and technology skills…

  9. Polarised Black Holes in AdS

    CERN Document Server

    Costa, Miguel S; Oliveira, Miguel; Penedones, João; Santos, Jorge E

    2015-01-01

    We consider solutions in Einstein-Maxwell theory with a negative cosmological constant that asymptote to global $AdS_{4}$ with conformal boundary $S^{2}\\times\\mathbb{R}_{t}$. At the sphere at infinity we turn on a space-dependent electrostatic potential, which does not destroy the asymptotic $AdS$ behaviour. For simplicity we focus on the case of a dipolar electrostatic potential. We find two new geometries: (i) an $AdS$ soliton that includes the full backreaction of the electric field on the $AdS$ geometry; (ii) a polarised neutral black hole that is deformed by the electric field, accumulating opposite charges in each hemisphere. For both geometries we study boundary data such as the charge density and the stress tensor. For the black hole we also study the horizon charge density and area, and further verify a Smarr formula. Then we consider this system at finite temperature and compute the Gibbs free energy for both $AdS$ soliton and black hole phases. The corresponding phase diagram generalizes the Hawkin...

  10. A study of the impact of adding HPV types to cervical cancer screening and triage tests.

    Science.gov (United States)

    Schiffman, Mark; Khan, Michelle J; Solomon, Diane; Herrero, Rolando; Wacholder, Sholom; Hildesheim, Allan; Rodriguez, Ana Cecilia; Bratti, Maria C; Wheeler, Cosette M; Burk, Robert D

    2005-01-19

    Use of human papillomavirus (HPV) testing in cervical cancer prevention is increasing rapidly. A DNA test for 13 HPV types that can cause cervical cancer is approved in the United States for co-screening with cytology of women >or=30 years old and for triage of women of all ages with equivocal cytology. However, most infections with HPV are benign. We evaluated trade-offs between specificity and sensitivity for approximately 40 HPV types in predicting cervical intraepithelial neoplasia 3 and cancer in two prospective studies: a population-based screening study that followed 6196 women aged 30-94 years from Costa Rica for 7 years and a triage study that followed 3363 women aged 18-90 years with equivocal cytology in four U.S. centers for 2 years. For both screening and triage, testing for more than about 10 HPV types decreased specificity more than it increased sensitivity. The minimal increases in sensitivity and in negative predictive value achieved by adding HPV types to DNA tests must be weighed against the projected burden to thousands of women falsely labeled as being at high risk of cervical cancer.

  11. Thinking Relationally about Studying "Up"

    Science.gov (United States)

    Stich, Amy E.; Colyar, Julia E.

    2015-01-01

    In this paper, the authors argue that despite a resurgence of elite studies, the majority of existing scholarship works to reify and legitimize social inequality through its language and method. In particular, the authors utilize Pierre Bourdieu's concept of relational thinking to review and critique contemporary research on elite education and…

  12. Defects in higher-dimensional quantum field theory. Relations to AdS/CFT-correspondence and Kondo lattices

    Energy Technology Data Exchange (ETDEWEB)

    Schmidt, R.

    2007-03-15

    The present work is addressed to defects and boundaries in quantum field theory considering the application to AdS/CFT correspondence. We examine interactions of fermions with spins localised on these boundaries. Therefore, an algebra method is emphasised adding reflection and transmission terms to the canonical quantisation prescription. This method has already been applied to bosons in two space-time dimensions before. We show the possibilities of such reflection-transmission algebras in two, three, and four dimensions. We compare with models of solid state physics as well as with the conformal field theory approach to the Kondo effect. Furthermore, we discuss ansatzes of extensions to lattice structures. (orig.)

  13. Fundamental study of the austenite formation and decomposition in low-silicon, aluminum added TRIP steels

    Science.gov (United States)

    Garcia-Gonzalez, Jose Enrique

    2005-11-01

    TRIP (Transformation Induced Plasticity) steels are under development for automotive applications that require high strength and excellent formability. Conventional TRIP steels consist of a multiphase microstructure comprised of a ferrite matrix with a dispersion of bainite and metastable retained austenite. The high ductility exhibited by these steels results from the transformation of the metastable retained austenite to martensite during straining. In conventional TRIP steel processing, the multiphase microstructure is obtained by controlled cooling from the alpha + gamma region to an isothermal holding temperature. During this holding, bainite forms and carbon is rejected out into the austenite, which lowers the Ms temperature and stabilizes the austenite to room temperature. In this research project, a fundamental study of a low-Si, Mo-Nb added cold rolled TRIP steel with and without Al additions was conducted. In this study, the recrystallization of cold-rolled ferrite, the formation of austenite during intercritical annealing and the characteristics of the decomposition of the intercritically annealed austenite by controlled cooling rates were systematically assessed. Of special interest were: (i) the effect of the initial hot band microstructure, (ii) the formation of epitaxial ferrite during cooling from the intercritical annealing temperature to the isothermal holding temperature, (iii) the influence of the intercritically annealed austenite on the formation of bainite during the isothermal holding temperature, and (iv) the influence of the processing variables on the type, amount, composition and stability of the retained austenite. During this research study, techniques such as OM, SEM, EBSD, TEM, XRD and Magnetometry were used to fully characterize the microstructures. Furthermore, a Gleeble 3500 unit at US Steel Laboratories was used for dilatometry studies and to simulate different CGL processing routes, from which specimens were obtained to evaluate

  14. Studying Intergroup Relations in Organizations.

    Science.gov (United States)

    1980-01-10

    23, 137-149. Sumner, W.G.: Folkways. New York; Ginn, 1906. Tajfel , H.: Experiments in Intergroup Discrimination . Scientific American, 1970, 223, 96-102...Shepard and Mouton’s (1964) subsequent studies and application to managerial behavior. Tajfel (1971) has carried out an extensive series of experiments on...and to influ- ence relations with other groups (Sherif and Sherif, 1969; Blake, Shepard, and Mouton, 1964; Tajfel , 1971; Billig, 1976). e. Leadership

  15. Study on the Improvement of Ad Hoc Network Routing Protocol AODV Efficient%高效的Ad Hoc网络AODV改进路由协议研究

    Institute of Scientific and Technical Information of China (English)

    陆彩霞

    2015-01-01

    Ad Hoc网络是一个自治系统,有临时多跳的特点,目前应用广泛,是当前研究热点之一.因为Ad Hoc网络拓扑结构变化频繁,本文对AODV路由协议进行了改进,研究出R_EAODV路由协议.%Ad Hoc network is a multi hop temporary autonomous system, has the characteristics of wide application, at present, is one of the hottest research topics. Because the Ad Hoc network topology changes frequently, this paper presents an improved AODV routing protocol, R_EAODV routing protocol research.

  16. 基于OPNET的Ad Hoc网络FSR路由协议的研究%Study of OPNET-Based FSR Routing Protocol in Ad Hoc Network

    Institute of Scientific and Technical Information of China (English)

    郭静

    2013-01-01

      This paper is about how to achieve the development and implementation of FSR routing protocol in Ad hoc network based on OPNET simulation framework. The analysis of the routing protocol FSR based on table-driven is followed by the implementation of the protocol via OPNET modeling simulation tool in terms of Ad hoc network features. The application prospect of FSR in Ad hoc network is obtained through the comparison of performances such as time delay and load of FSR, AODV and OLSR.%  本文阐述了基于OPNET仿真框架下,如何实现Ad hoc网络中FSR路由协议的开发实现。针对Ad hoc网络特点的分析,分析基于表驱动的路由协议FSR,并通过OPNET建模仿真工具来实现该协议。通过 FSR 与 AODV、OLSR 进行时延和负载方面的性能比较,得出 FSR在Ad hoc网络中应用前景。

  17. AdS orbifolds and Penrose limits

    Energy Technology Data Exchange (ETDEWEB)

    Alishahiha, Mohsen; Sheikh-Jabbari, Mohammad M.; Tatar, Radu

    2002-12-09

    In this paper we study the Penrose limit of AdS{sub 5} orbifolds. The orbifold can be either in the pure spatial directions or space and time directions. For the AdS{sub 5}/{Lambda} x S{sup 5} spatial orbifold we observe that after the Penrose limit we obtain the same result as the Penrose limit of AdS{sub 5} x S{sup 5}/{Lambda}. We identify the corresponding BMN operators in terms of operators of the gauge theory on R x S{sup 3}/{Lambda}. The semi-classical description of rotating strings in these backgrounds have also been studied. For the spatial AdS orbifold we show that in the quadratic order the obtained action for the fluctuations is the same as that in S{sup 5} orbifold, however, the higher loop correction can distinguish between two cases.

  18. Study of Impact of Mobile Ad hoc Networking and its Future Applications

    Directory of Open Access Journals (Sweden)

    Ashema Hasti

    2012-01-01

    Full Text Available Today, many people carry numerous portable devices, such as laptops, mobile phones, PDAs and mp3 players, for use in their professional and private lives. For the most part, these devices are used separately-that is, their applications do not interact. Imagine, however, if they could interact directly: participants at a meeting could share documents or presentations; all communication could automatically be routed through the wireless corporate campus network. These examples of spontaneous, ad hoc wireless communication between devices might be loosely defined as a scheme, often referred to as ad hoc networking, which allows devices to establish communication, anytime and anywhere without the aid of a central infrastructure. This paper describes the concept of mobile ad hoc networking (MANET and points out some of its applications that can be envisioned for future. Also, the paper presents two of the technical challenges MANET poses, which include Geocasting and QoS.

  19. The FLUKA study of the secondary particles fluence in the AD-Antiproton Decelerator target area

    CERN Document Server

    Calviani, M

    2014-01-01

    In this paper we present Monte Carlo FLUKA simulations [1, 2] carried out to investigate the secondary particles fluence emerging from the antiproton production target and their spatial distribution in the AD target area. The detailed quantitative analysis has been performed for different positions along the magnet dog-leg as well as after the main collimator. These results allow tuning the position of the new beam current transformers (BCT) in the target area, in order to have a precise pulse-by-pulse evaluation of the intensity of negative particles injected in the AD-ring before the deceleration phase.

  20. The Study of Routing Strategies in Vehicular Ad- Hoc Network to Enhance Security

    Directory of Open Access Journals (Sweden)

    Parveen Kumar

    2012-04-01

    Full Text Available In VANET, or Intelligent Vehicular Ad-HocNetworking, defines an intelligent way of usingVehicular Networking. In VANET integrates onmultiple ad-hoc networking technologies such as WIFIIEEE 802.11p, WAVE IEEE 1609, WIMAX IEEE802.16, Bluetooth, IRA, and ZIGBEE for easy,accurate, effective and simple communication betweenvehicles on dynamic mobility. Effective measuressuch as media communication between vehicles canbe enabled as well as methods to track the automotivevehicles. In VANET helps in defining safety measuresin vehicles, streaming communication betweenvehicles, infotainment and TELEMATICS.

  1. Reconstruction of the western Pacific warm pool SST since 1644 AD and its relation to precipitation over East China

    Institute of Scientific and Technical Information of China (English)

    2009-01-01

    Based on coral proxies we reconstructed the western Pacific warm pool sea surface temperature (SST) since 1644 AD. High-frequency reconstructions are based on eight high-pass filtered coral series and raw reconstructions are derived from eight unfiltered coral series, respectively. Validation and comparison with other SST/temperature series show that the reconstructed warm pool SST is highly reliable. The leading periods of warm pool SST are ~2.1, ~2.3, ~2.9, ~3.6, ~3.8, and 80.7-year during the last ~360 years. The warm pool SST exhibits some obvious long-term trends: an upward trend of 0.04℃ per century for the period of 1644―1825, while a decreasing trend of 0.24℃ per century for the period of 1826―1885, and then a remarkable warming trend of 0.28℃ per century taking place between 1886 and 2006. Especially, the SST shows the strongest trend of 0.67℃ increase per century during the last 50 years, a warming unprecedented since 1644 AD. On interannual timescale, the connections between ENSO and the warm pool SST are robust during the reconstruction period. There are significant corre- lations between the warm pool SST and summer precipitation of the Yellow River basin and Huaihe River basin; the correlation coefficients are -0.44 in reconstruction period (1880―1949 AD) and -0.46 in instrumental period (1950―2005 AD) respectively. This relationship is also found between flooddrought index and the warm pool SST during the past 360 years, and their correlation coefficients are -0.20 in reconstruction period and-0.46 in instrumental period respectively, significant at the 0.01 level. On interdecadal timescale, this connection is more robust, and the correlation coefficient of the low-pass filtered components is -0.42 during the whole period (1644―2000 AD). When the warm pool is warmer than normal, the precipitation is usually below the normal in the Yellow River and Huaihe River basin. On the contrary, when the warm pool is colder than the normal

  2. Reconstruction of the western Pacific warm pool SST since 1644 AD and its relation to precipitation over East China

    Institute of Scientific and Technical Information of China (English)

    ZHANG ZiYin; GONG DaoYi; HE XueZhao; GUO Dong; FENG ShengHui

    2009-01-01

    Based on coral proxies we reconstructed the western Pacific warm pool sea surface temperature (SST) since 1644 AD.High-frequency reconstructions are based on eight high-pass filtered coral series and raw reconstructions are derived from eight unfiltered coral series,respectively.Validation and comparison with other SST/temperature series show that the reconstructed warm pool SST is highly reliable.The leading periods of warm pool SST are ~2.1,~2.3,~2.9,~3.6,~3.8,and 80.7-year during the last ~360 years.The warm pool SST exhibits some obvious long-term trends:an upward trend of 0.04℃ per century for the period of 1644-1825,while a decreasing trend of 0.24℃ per century for the period of 1826-1885,and then a remarkable warming trend of 0.28℃ per century taking place between 1886 and 2006.Especially,the SST shows the strongest trend of 0.67℃ increase per century during the last 50 years,a warming unprecedented since 1644 AD.On interannual timescale,the connections between ENSO and the warm pool SST are robust during the reconstruction period.There are significant correlations between the warm pool SST and summer precipitation of the Yellow River basin and Huaihe River basin;the correlation coefficients are-0.44 in reconstruction period (1880-1949 AD) and -0.46 in instrumental period (1950-2005 AD) respectively.This relationship is also found between flooddrought index and the warm pool SST during the past 360 years,and their correlation coefficients are -0.20 in reconstruction period and -0.46 in instrumental period respectively,significant at the 0.01 level.On interdecadal timescale,this connection is more robust,and the correlation coefficient of the low-pass filtered components is -0.42 during the whole period (1644-2000 AD).When the warm pool is warmer than normal,the precipitation is usually below the normal in the Yellow River and Huaihe River basin.On the contrary,when the warm pool is colder than the normal,there may be more precipitation

  3. Design Study of Full Scale Accelerator Driven System (ADS, for Transmuting High Level Waste of MA/Pu

    Directory of Open Access Journals (Sweden)

    Marsodi

    2008-07-01

    Full Text Available The ADS system used in this study consisting of a high intensity proton linear accelerator, a spallation target, and a sub-critical reactor core. The Pb-Bi spallation target is bombarded by high intensity protons coming from the accelerator. The fast neutrons generated from the spallation reaction were used to drive the sub-critical reactor core. In this ADS system, the neutron source is in the center of reactor core region, so that the neutron distribution was concentrated in the center of core region. In this case, the B/T of MA/Pu could be performed effectively in the center of core region. The neutron energy in the outer region of reactor core was decreased due to the moderation of fuel and coolant materials. Such condition gives a chance to perform Burning and/or Transmutation of LLFPs.The basic parameters of this system are shown in the form of neutronic design, neutron spectrum and B/T rate, including other aspects related to the safety operation system. Furthermore, the analysis of the ADS system was accomplished using ATRAS computer code of the Japan Atomic Energy Research Institute, JAERI[1]. Due to the complexity of the reactor calculation codes, the author has carried out only those calculations needed for analyzing the neutronics system and some parameters related to the safety system. Design study of the transmutation system was a full-scale power level system of 657.53 MWt sub-critical reactor for an accelerator-driven transmutation system. The liquid Pb-Bi was used together as the spallation target materials and coolant of the system, because of some advantages of Pb-Bi in the system concerning the comparison with the sodium coolant. Moreover, they have a possibility to achieve a hard neutron energy spectrum, avoid a positive void reactivity coefficient, allow much lower system operating temperatures, and are favorable for safety in the event of coolant leakage. The multiplication factor of sub-critical core design was adjusted

  4. Value added analysis and its distribution: a study on BOVESPA-listed banks using ANOVA

    Directory of Open Access Journals (Sweden)

    Leonardo José Seixas Pinto

    2013-05-01

    Full Text Available The value added generated by the financial institutions listed on BOVESPA and its distribution in the years between 2007 to 2011 are the subject of this research which shows how banks divided his wealth with the people, government, third parties and shareholders. Through the use of ANOVA test average in the companies that took part in this research concluded that: (a the average value added of foreign banks differs from national banks. (b The remuneration policy of equity foreign banks differs from national banks. (c The policy of distribution of value added to employees of foreign banks Santander and HSBC differs from the other banks. (d Taxes paid to the government have equal means with the exception of Santander. (e Although curious, Banco Itau and Banco do Brazil is equal in all analyzes in the distribution of value added since it is a private and one public. It appears this way a policy unequal distribution of wealth generation and foreign banks compared with the national public and private banks.

  5. Incentive-based control of ad hoc networks: a performance study

    NARCIS (Netherlands)

    Göbel, F.; Kresinski, A.E.; Mandjes, M.R.H.

    2009-01-01

    Ad hoc networks are self-configuring networks of mobile nodes, connected by wireless links. If a destination node is beyond the transmission range of an origin node, then the nodes must cooperate to provide a multi-hop route. Any node can act as a sender, receiver or transit node. It is clear that i

  6. Multipath routing and multiple description coding in ad-hoc networks: A simulation study

    NARCIS (Netherlands)

    Díaz, I.F.; Epema, D.; Jongh, J. de

    2004-01-01

    The nature of wireless multihop ad-hoc networks makes it a challenge to offer connections of an assured quality. In order to improve the performance of such networks, multipath routing in combination with Multiple Description Coding (MDC) has been proposed. By splitting up streams of multimedia traf

  7. Inuloxins A-D and derivatives as antileishmanial agents: structure-activity relationship study

    Science.gov (United States)

    Inuloxins A-D (1-4) and a-costic acid (5), the phytotoxic compounds previously isolated from Inula viscosa, as well as synthetic derivatives of inuloxin A (compounds 6-10), inuloxin C (compound 11) and inuloxin D (compound 12) were tested in vitro for their activity against Leishmania donovani, the ...

  8. The Added Value of Water Footprint Assessment for National Water Policy: A Case Study for Morocco

    NARCIS (Netherlands)

    Schyns, Joep F.; Hoekstra, Arjen Y.

    2014-01-01

    A Water Footprint Assessment is carried out for Morocco, mapping the water footprint of different activities at river basin and monthly scale, distinguishing between surface- and groundwater. The paper aims to demonstrate the added value of detailed analysis of the human water footprint within a cou

  9. Vallue-added tax fraud within the European Union : pilot study

    NARCIS (Netherlands)

    Aronowitz, A.A.; Laagland, D.C.G.; Paulides, G.

    1995-01-01

    This research project, to a certain degree, aims at filling the knowledge gap concerning organized business crime by highlighting one specific phenomenon, that of cross-border Vallue-Added Tax (VAT) fraud within the European Union. Insight is to be provided into: a) the effectiveness of the present

  10. Refined Holographic Entanglement Entropy for the AdS Solitons and AdS black Holes

    CERN Document Server

    Ishihara, Masafumi; Ning, Bo

    2012-01-01

    We consider the refinement of the holographic entanglement entropy on a disk region for the holographic dual theories to the AdS solitons and AdS black holes, including the corrected ones by the Gauss-Bonnet term. The AdS soliton is dual to a gapped system with an IR fixed-point. The refinement is obtained by extracting the UV-independent piece of the holographic entanglement entropy. We then study the renormalization group (RG) flow of the refinement by tuning the linear size of the chosen disk region. Our main results are (i) the RG flow of the refinement decreases monotonically for most of the cases; (ii) there is no topological entanglement entropy for AdS$_5$ soliton even with Gauss-Bonnet correction; (iii) for the AdS black holes, the refinement obeys the volume law at IR regime, and the transition between UV and IR regimes is a smooth crossover; however, the crossover will turn into phase transition by the Gauss-Bonnet correction; (iv) for the AdS solitons, there are discontinuous phase transitions bet...

  11. A Study of Connectivity in MIMO Fadinc Ad-Hoc Networks

    Science.gov (United States)

    2008-08-04

    with a finite num- ber of mobile nodes. Some of the related articles in this area are [5], [20], [3], and [6]. Interestingly, connectiv - ity in random...of 1000 square meters according to a Poisson point process [13]. When measuring connectiv - ity, we assume all of the nodes can transmit at the same...thorough understanding of the connectiv - ity phenomenon. While this work has proposed analyt- ical measures for studying connectivity, we are

  12. Note on classical string dynamics on AdS3

    Science.gov (United States)

    Bañados, Máximo; Ritz, Adam

    1999-12-01

    We consider bosonic strings propagating on Euclidean anti-de Sitter space (AdS3), and study in particular the realization of various worldsheet symmetries. We give a proper definition for the Brown-Henneaux asymptotic target space symmetry, when acting on the string action, and derive the Giveon-Kutasov-Seiberg worldsheet contour integral representation simply by using Noether's theorem. We show that making identifications in the target space is equivalent to the insertion of an (exponentiated) graviton vertex operator carrying the corresponding charge. Finally, we point out an interesting relation between 3D gravity and the dynamics of the worldsheet on AdS3. Both theories are described by an SL(2,C)/SU(2) Wess-Zumino-Witten (WZW) model, and we prove that the reduction conditions determined on one hand by worldsheet diffeomorphism invariance, and on the other by the Brown-Henneaux boundary conditions, are the same.

  13. Observing quantum gravity in asymptotically AdS space

    Science.gov (United States)

    Emelyanov, Slava

    2015-12-01

    The question is studied of whether an observer can discover quantum gravity in the semiclassical regime. It is shown that it is indeed possible to probe a certain quantum gravity effect by employing an appropriately designed detector. The effect is related to the possibility of having topologically inequivalent geometries in the path-integral approach at the same time. A conformal field theory (CFT) state which is expected to describe the eternal anti-de Sitter (AdS) black hole in the large-N limit is discussed. It is argued under certain assumptions that the black hole boundary should be merely a patch of the entire AdS boundary. This leads then to a conclusion that that CFT state is the ordinary CFT vacuum restricted to that patch. If existent, the bulk CFT operators can behave as the ordinary semiclassical quantum field theory in the large-N limit in the weak sense.

  14. An Empirical Comparative Study of Checklist-based and Ad Hoc Code Reading Techniques in a Distributed Groupware Environment

    Directory of Open Access Journals (Sweden)

    Adenike O. Osofisan

    2009-09-01

    Full Text Available Software inspection is a necessary and important tool for software quality assurance. Since it was introduced by Fagan at IBM in 1976, arguments exist as to which method should be adopted to carry out the exercise, whether it should be paper-based or tool-based, and what reading technique should be used on the inspection document. Extensive works have been done to determine the effectiveness of reviewers in paper-based environment when using ad hoc and checklist reading techniques. In this work, we take the software inspection research further by examining whether there is going to be any significant difference in defect detection effectiveness of reviewers when they use either ad hoc or checklist reading techniques in a distributed groupware environment. Twenty final year undergraduate students of computer science, divided into ad hoc and checklist reviewers groups of ten members each were employed to inspect a medium-sized java code synchronously on groupware deployed on the Internet. The data obtained were subjected to tests of hypotheses using independent t-test and correlation coefficients. Results from the study indicate that there are no significant differences in the defect detection effectiveness, effort in terms of time taken in minutes and false positives reported by the reviewers using either ad hoc or checklist based reading techniques in the distributed groupware environment studied.Key words: Software Inspection, Ad hoc, Checklist, groupware.

  15. Adding Ajax

    CERN Document Server

    Powers, Shelley

    2007-01-01

    Ajax can bring many advantages to an existing web application without forcing you to redo the whole thing. This book explains how you can add Ajax to enhance, rather than replace, the way your application works. For instance, if you have a traditional web application based on submitting a form to update a table, you can enhance it by adding the capability to update the table with changes to the form fields, without actually having to submit the form. That's just one example.Adding Ajax is for those of you more interested in extending existing applications than in creating Rich Internet Applica

  16. The Added Value of Water Footprint Assessment for National Water Policy: A Case Study for Morocco

    OpenAIRE

    2014-01-01

    A Water Footprint Assessment is carried out for Morocco, mapping the water footprint of different activities at river basin and monthly scale, distinguishing between surface- and groundwater. The paper aims to demonstrate the added value of detailed analysis of the human water footprint within a country and thorough assessment of the virtual water flows leaving and entering a country for formulating national water policy. Green, blue and grey water footprint estimates and virtual water flows ...

  17. Boson Stars in AdS

    CERN Document Server

    Buchel, Alex; Lehner, Luis

    2013-01-01

    We construct boson stars in global Anti de Sitter (AdS) space and study their stability. Linear perturbation results suggest that the ground state along with the first three excited state boson stars are stable. We evolve some of these solutions and study their nonlinear stability in light of recent work \\cite{Bizon:2011gg} arguing that a weakly turbulent instability drives scalar perturbations of AdS to black hole formation. However evolutions suggest that boson stars are nonlinearly stable and immune to the instability for sufficiently small perturbation. Furthermore, these studies find other families of initial data which similarly avoid the instability for sufficiently weak parameters. Heuristically, we argue that initial data families with widely distributed mass-energy distort the spacetime sufficiently to oppose the coherent amplification favored by the instability. From the dual CFT perspective our findings suggest that there exist families of rather generic initial conditions in strongly coupled CFT ...

  18. A Comparative Study on the Uptake and Toxicity of Nickel Added in the Form of Different Salts to Maize Seedlings

    Directory of Open Access Journals (Sweden)

    Jing Nie

    2015-11-01

    Full Text Available In soil ecotoxicological studies, a toxic metal is usually added in the form of either an inorganic or organic salt with relatively high solubility. Nitrate, chloride, acetate, or sulfate are commonly considered as valid options for that aim. However, recent studies have shown that different salts of the same metal at the same cationic concentration may exhibit different toxicities to plants and soil organisms. This information should be considered when selecting data to use for developing toxicological criteria for soil environment. A comparative study was carried out to evaluate the toxicity of five nickel (Ni salts: NiCl2, NiSO4, Ni(II-citrate, Ni(CH3COO2, and Ni(II-EDTA (ethylenediaminetetraacetate, on maize seedlings. The plant metrics used were plant height, shoot and root biomass, leaf soluble sugars and starch, and the Ni contents of the shoots and roots. The results indicated that when Ni was added to the soil, toxicity varied with the selected anionic partner with the following toxicity ranking NiSO4 < Ni(CH3COO2 < Ni(II-citrate < NiCl2 < Ni(II-EDTA. Taking the plant-height metric as an example, the effective concentrations for 50% inhibition (EC50 were 3148 mg·kg−1 for NiSO4, 1315 mg·kg−1 for NiCl2, and 89 mg·kg−1 for Ni(II-EDTA. Compared with the Ni in the other salts, that in Ni(II-EDTA was taken up the most efficiently by the maize roots and, thus, resulted in the greatest toxic effects on the plants. Nickel generally reduced leaf soluble sugars, which indicated an effect on plant carbohydrate metabolism. The outcome of the study demonstrates that different salts of the same metal have quite different ecotoxicities. Therefore, the anionic counterpart of a potentially toxic metal cation must be taken into account in the development of ecotoxicological criteria for evaluating the soil environment, and a preferred approach of leaching soil to reduce the anionic partner should also be considered.

  19. Experimental performance study of wireless ad hoc system utilizing 802.11a standard base on different routing protocols

    Science.gov (United States)

    Zhong, Xiao F.; Wang, You-Zheng; Mei, Shunliang; Wang, Jing

    2002-08-01

    The wireless ad hoc network technology provides a flexible infrastructure for next generation mobile telecommunication. In this paper, the performances of the networks based on IEEE802.11a standard, including packets successful delivery rate, average end-to-end delay and system throughput, have been studied with different routing protocols (AODV, WRP, and FISHEYE) using GloMoSim to evaluate the effects of various factors, such as node mobility, node density, and node radio transmission range. The simulation results show that adaptive routing protocol will be more suitable for the variation ad hoc network and the results are helpful for the optimum design and deployment of an actual network.

  20. Design and rationale for RE-VERSE AD : A phase 3 study of idarucizumab, a specific reversal agent for dabigatran

    NARCIS (Netherlands)

    Pollack, Charles V.; Reilly, Paul A.; Bernstein, Richard; Dubiel, Robert; Eikelboom, John; Glund, Stephan; Huisman, Menno V.; Hylek, Elaine; Kam, Chak-Wah; Kamphuisen, Pieter W.; Kreuzer, Joerg; Levy, Jerrold H.; Sellke, Frank; Stangier, Joachim; Steiner, Thorsten; Wang, Bushi; Weitz, Jeffrey I.

    2015-01-01

    Idarucizumab, a Fab fragment directed against dabigatran, produced rapid and complete reversal of the anticoagulation effect of dabigatran in animals and in healthy volunteers. The Study of the REVERSal Effects of Idarucizumab in Patients on Active Dabigatran (RE-VERSE AD (TM)) is a global phase 3 p

  1. 基于位置的Ad hoc网络路由协议研究%Study on Location-based Unicast Routing Protocol for Ad hoc Network

    Institute of Scientific and Technical Information of China (English)

    孟积渐; 刘禹

    2012-01-01

    基于位置的Ad hoc网络路由协议利用节点地理位置信息指导数据包的转发,具有可扩展性强,路由效率高等优点。分析了Ad hoc网络中基于位置的路由协议以及位置信息服务,对几种协议进行了分析比较,并指出了基于位置的路由协议的研究重点。%iLocation-based unicast routing protocol uses geographical location information of nodes to direct the forward of data package,superior to scalability and high efficiency in routing.In this paper,we introduced location-based unicast Routing Protocols and location information services for Ad hoc network.Analysed and compared several protocols,we pointed at the research emphasis on location-based unicast routing protocol.

  2. BACE1 RNAi restores the composition of phosphatidylethanolamine-derivates related to memory improvement in aged 3xTg-AD mice

    Directory of Open Access Journals (Sweden)

    Javier Gustavo Villamil

    2016-11-01

    Full Text Available β-amyloid (Aβ is produced by the β-secretase 1 (BACE1-mediated enzymatic cleavage of the amyloid precursor protein through the amyloidogenic pathway, making BACE1 a therapeutic target against Alzheimer’s Disease (AD. Alterations in lipid metabolism are a risk factor for AD by an unknown mechanism. The objective of this study was to determine the effect of RNA interference against BACE1 (shBACEmiR on the phospholipid profile in hippocampal CA1 area in aged 3xTg-AD mice after 6 and 12 months of treatment compared to aged PS1KI mice. The shBACEmiR treatment induced cognitive function recovery and restored mainly the fatty acid composition of lysophosphatidylethanolamine (LPE and etherphosphatidylethanolamine (ePE, reduced the cPLA2’s phosphorylation, down-regulated the levels of arachidonic acid (AA and COX2 in the hippocampi of 3xTg-AD mice. Together, our findings suggest, for the first time, that BACE1 silencing restores phospholipids composition which could favor the recovery of cellular homeostasis and cognitive function in the hippocampus of triple transgenic AD mice.

  3. BACE1 RNAi Restores the Composition of Phosphatidylethanolamine-Derivates Related to Memory Improvement in Aged 3xTg-AD Mice

    Science.gov (United States)

    Villamil-Ortiz, Javier G.; Barrera-Ocampo, Alvaro; Piedrahita, Diego; Velásquez-Rodríguez, Claudia M.; Arias-Londoño, Julian D.; Cardona-Gómez, Gloria P.

    2016-01-01

    β-amyloid (Aβ) is produced by the β-secretase 1 (BACE1)-mediated enzymatic cleavage of the amyloid precursor protein through the amyloidogenic pathway, making BACE1 a therapeutic target against Alzheimer’s disease (AD). Alterations in lipid metabolism are a risk factor for AD by an unknown mechanism. The objective of this study was to determine the effect of RNA interference against BACE1 (shBACEmiR) on the phospholipid profile in hippocampal CA1 area in aged 3xTg-AD mice after 6 and 12 months of treatment compared to aged PS1KI mice. The shBACEmiR treatment induced cognitive function recovery and restored mainly the fatty acid composition of lysophosphatidylethanolamine and etherphosphatidylethanolamine, reduced the cPLA2’s phosphorylation, down-regulated the levels of arachidonic acid and COX2 in the hippocampi of 3xTg-AD mice. Together, our findings suggest, for the first time, that BACE1 silencing restores phospholipids composition which could favor the recovery of cellular homeostasis and cognitive function in the hippocampus of triple transgenic AD mice. PMID:27891075

  4. Exploring antismoking ads: appeals, themes, and consequences.

    Science.gov (United States)

    Beaudoin, Christopher E

    2002-01-01

    In this study we seek a descriptive understanding of antismoking television advertising in light of the problem cigarette consumption poses for society today. We establish relationships between ad characteristics and whether ads have a youth or adult orientation, based on a content analysis of 197 antismoking television advertisements produced between 1991 and 1999. The study finds that youth-oriented ads have youth characters, sociability, and humor as common appeals, and social and short-term consequences. In contrast, adult-oriented ads relied on fear appeals and long-term, health-related consequences.

  5. Capacity and performance study of IEEE 802.11e in WLANs and ad hoc networks

    OpenAIRE

    Mjøberg, Frank Roar

    2007-01-01

    This master thesis focuses on the IEEE 802.11e Enhanced Distribution Channel Access (EDCA). The IEEE 802.11e protocol became an IEEE standard in November 2005 and is a very popular research topic. Even though the protocol has been tested for faults and errors a long time there are still research topics to explore. This thesis will try to answer some of those topics. The main topic in this thesis is how the IEEE 802.11e MAC operates in a multihop ad hoc network. We discuss and evaluated th...

  6. Study of Un-added Allowance of Draping-Planar Designing Garment Prototype for Young Ladies

    Institute of Scientific and Technical Information of China (English)

    李兴刚; 李元虹; 苏同岳

    2003-01-01

    As for the theory and method in garment structural design according to human figures,a principle for garment design,i.e.body-fitting without added allowance,and a combination of draping and planar design (DPD hereunder) for young ladies has been put forward,and,also,a DPD garment prototype for them has been established.And the applied formulae for extensively-practicing operation have been set up,which proves to be,with actual samples,a systematic and practical garment structural designing theory and approach.

  7. D-branes in Lorentzian AdS(3)

    CERN Document Server

    Israel, D

    2005-01-01

    We study the exact construction of D-branes in Lorentzian AdS(3). We start by defining a family of conformal field theories that gives a natural Euclidean version of the SL(2,R) CFT and does not correspond to H(3)+, the analytic continuation of AdS(3). We argue that one can recuperate the exact CFT results of Lorentzian AdS(3), upon an analytic continuation in the moduli space of these conformal field theories. Then we construct exact boundary states for various symmetric and symmetry-breaking D-branes in AdS(3).

  8. Effects of dietary vanadium on growth and lipid storage in a larval anuran: results from studies employing ad libitum and rationed feeding.

    Science.gov (United States)

    Rowe, Christopher L; Heyes, Andrew; Hopkins, William

    2009-01-31

    Vanadium (V) exerts a variety of effects related to metabolic function in vertebrates, including modifying glycolytic pathways and lipid metabolism. However, little is known about toxicity of V to wildlife in natural systems. We conducted parallel, independent studies to evaluate the effect of dietary exposure to vanadium on survival, metabolism, growth, and lipid storage of larval leopard frogs (Rana sphenocephala). In one study ("Ad lib") larvae were fed unlimited food and in the other ("Ration") larvae were fed a restricted diet. Experimental diets contained 10 ppm dw V(total) (Control, "C"), 109 ppm (Low, "L"), and 363 ppm (High, "H"). In neither study did V affect metabolic rate or survival to forelimb emergence. However, in the Ration study, 31% of individuals in H that had initiated metamorphosis died prior to completion of metamorphosis, compared with 22% in M and 9% in C, however the difference was not significant at alpha=0.05. Mortality during metamorphosis in the Ad lib study was more variable, yet followed a similar trend (26, 14, and 12% mortality in H, L, and C). In both studies, individuals that died during the metamorphic period were smaller at the time of forelimb emergence than those that survived. In the Ration study, individuals in H also had significantly lower growth rates, delayed metamorphosis, and reduced lipid content at metamorphosis compared to C and L. Growth was not affected by V in the Ad lib study. Our results suggest that habitat contamination by V may present risks to amphibians during the metamorphic period attributable to energetic responses influencing size at the initiation of metamorphosis and body lipid stores. Furthermore, while we cannot make formal comparisons between the studies, our results imply that protocols that employ ad libitum feeding regimes could fail to capture the effects of contaminants as they may be expressed in natural situations in which resources are typically more limited.

  9. A study of the properties and functions of CMC-bonial BBV/ADS; Estudo das propriedades e funcoes do CMC-bonial BBV/ADS

    Energy Technology Data Exchange (ETDEWEB)

    Oliveira, Telma de; S. Filho, Antonio Alves [Grupo Ultra, XX (Brazil)

    1989-12-31

    The use of CMC (Carboxy methyl cellulose) in drilling fluids is consolidated in the national and international markets. Properties such as water retention, rheology control and viscosifying capacity have made this polymer a largely used additive for drilling fluids. The goal of this paper is to stress the effects of the use of low viscosity CMC (Bonial BBV/ADS). We stress also filtrate reduction and control of the rheological properties of the fluid, through flow limits. We demonstrate the effects of substitution degree and molecular weight, through viscosity, on the properties required for application. (author) 6 refs., 9 figs., 4 tabs.

  10. Feasibility study of a wearable exoskeleton for children: is the gait altered by adding masses on lower limbs?

    Directory of Open Access Journals (Sweden)

    Stefano Rossi

    Full Text Available We are designing a pediatric exoskeletal ankle robot (pediatric Anklebot to promote gait habilitation in children with Cerebral Palsy (CP. Few studies have evaluated how much or whether the unilateral loading of a wearable exoskeleton may have the unwanted effect of altering significantly the gait. The purpose of this study was to evaluate whether adding masses up to 2.5 kg, the estimated overall added mass of the mentioned device, at the knee level alters the gait kinematics. Ten healthy children and eight children with CP, with light or mild gait impairment, walked wearing a knee brace with several masses. Gait parameters and lower-limb joint kinematics were analyzed with an optoelectronic system under six conditions: without brace (natural gait and with masses placed at the knee level (0.5, 1.0, 1.5, 2.0, 2.5 kg. T-tests and repeated measures ANOVA tests were conducted in order to find noteworthy differences among the trial conditions and between loaded and unloaded legs. No statistically significant differences in gait parameters for both healthy children and children with CP were observed in the five "with added mass" conditions. We found significant differences among "natural gait" and "with added masses" conditions in knee flexion and hip extension angles for healthy children and in knee flexion angle for children with CP. This result can be interpreted as an effect of the mechanical constraint induced by the knee brace rather than the effect associated with load increase. The study demonstrates that the mechanical constraint induced by the brace has a measurable effect on the gait of healthy children and children with CP and that the added mass up to 2.5 kg does not alter the lower limb kinematics. This suggests that wearable devices weighing 25 N or less will not noticeably modify the gait patterns of the population examined here.

  11. Does adding risk-trends to survival models improve in-hospital mortality predictions? A cohort study

    Directory of Open Access Journals (Sweden)

    Forster Alan J

    2011-07-01

    Full Text Available Abstract Background Clinicians informally assess changes in patients' status over time to prognosticate their outcomes. The incorporation of trends in patient status into regression models could improve their ability to predict outcomes. In this study, we used a unique approach to measure trends in patient hospital death risk and determined whether the incorporation of these trend measures into a survival model improved the accuracy of its risk predictions. Methods We included all adult inpatient hospitalizations between 1 April 2004 and 31 March 2009 at our institution. We used the daily mortality risk scores from an existing time-dependent survival model to create five trend indicators: absolute and relative percent change in the risk score from the previous day; absolute and relative percent change in the risk score from the start of the trend; and number of days with a trend in the risk score. In the derivation set, we determined which trend indicators were associated with time to death in hospital, independent of the existing covariates. In the validation set, we compared the predictive performance of the existing model with and without the trend indicators. Results Three trend indicators were independently associated with time to hospital mortality: the absolute change in the risk score from the previous day; the absolute change in the risk score from the start of the trend; and the number of consecutive days with a trend in the risk score. However, adding these trend indicators to the existing model resulted in only small improvements in model discrimination and calibration. Conclusions We produced several indicators of trend in patient risk that were significantly associated with time to hospital death independent of the model used to create them. In other survival models, our approach of incorporating risk trends could be explored to improve their performance without the collection of additional data.

  12. Role of Adding Spironolactone and Renal Denervation in True Resistant Hypertension: One-Year Outcomes of Randomized PRAGUE-15 Study.

    Science.gov (United States)

    Rosa, Ján; Widimský, Petr; Waldauf, Petr; Lambert, Lukáš; Zelinka, Tomáš; Táborský, Miloš; Branny, Marian; Toušek, Petr; Petrák, Ondřej; Čurila, Karol; Bednář, František; Holaj, Robert; Štrauch, Branislav; Václavík, Jan; Nykl, Igor; Krátká, Zuzana; Kociánová, Eva; Jiravský, Otakar; Rappová, Gabriela; Indra, Tomáš; Widimský, Jiří

    2016-02-01

    This randomized, multicenter study compared the relative efficacy of renal denervation (RDN) versus pharmacotherapy alone in patients with true resistant hypertension and assessed the effect of spironolactone addition. We present here the 12-month data. A total of 106 patients with true resistant hypertension were enrolled in this study: 52 patients were randomized to RDN and 54 patients to the spironolactone addition, with baseline systolic blood pressure of 159±17 and 155±17 mm Hg and average number of drugs 5.1 and 5.4, respectively. Twelve-month results are available in 101 patients. The intention-to-treat analysis found a comparable mean 24-hour systolic blood pressure decline of 6.4 mm Hg, P=0.001 in RDN versus 8.2 mm Hg, P=0.002 in the pharmacotherapy group. Per-protocol analysis revealed a significant difference of 24-hour systolic blood pressure decline between complete RDN (6.3 mm Hg, P=0.004) and the subgroup where spironolactone was added, and this continued within the 12 months (15 mm Hg, P= 0.003). Renal artery computed tomography angiograms before and after 1 year post-RDN did not reveal any relevant changes. This study shows that over a period of 12 months, RDN is safe, with no serious side effects and no major changes in the renal arteries. RDN in the settings of true resistant hypertension with confirmed compliance is not superior to intensified pharmacological treatment. Spironolactone addition (if tolerated) seems to be more effective in blood pressure reduction.

  13. Experimental Study on Shear Fatigue Behavior and Stiffness Performance of Warm Mix Asphalt by adding Synthetic Wax

    CERN Document Server

    Petit, Christophe; Canestrari, Francesco; Pannunzio, Valter; Virgili, Amadeo

    2012-01-01

    Synthetic waxes produced by standard and registered processes may be used to manufacture Warm Mix Asphalt (WMA), which is a modified asphalt concrete produced, applied and compacted at temperatures below those typically required. This feature leads to environmental benefits, such as reduced energy consumption, gas and fume emissions, as well as to economic/operational advantages, such as lower production costs and greater hauling distances for extended construction seasons with tighter schedules. The present article serves to compare the mechanical performance of a WMA produced by adding synthetic wax with a traditional Hot Mix Asphalt (HMA) specimen, in terms of shear fatigue response and both complex and stiffness moduli. The experimental results and related modeling work demonstrate that adding synthetic wax into the WMA composition does not hinder either the destructive or non-destructive performance of an HMA, and this finding is corroborated by respectively measuring fatigue life and stiffness.

  14. Study on transient beam loading compensation for China ADS proton linac injector II

    CERN Document Server

    Gao, Zheng; Wang, Xian-Wu; Chang, Wei; Zhang, Rui-Feng; Zhu, Zheng-Long; Zhang, Sheng-Hu; Chen, Qi; Powers, Tom

    2016-01-01

    Significant transient beam loading effects were observed during beam commissioning tests of prototype II of the injector for the Accelerator Driven Sub-critical (ADS) system, which took place at the Institute of Modern Physics, Chinese Academy of Sciences, between October and December 2014. During these tests experiments were performed with CW operation of the cavities with pulsed beam current, and the system was configured to make use of a prototype digital low level radio frequency (LLRF) controller. The system was originally operated in pulsed mode with a simple PID feedback control algorithm, which was not able to maintain the desired gradient regulation during pulsed 10 mA beam operations. A unique simple transient beam loading compensation method which made use of a combination of PI feedback and feedforward control algorithm was implemented in order to significantly reduce the beam induced transient effect in the cavity gradients. The superconducting cavity field variation was reduced to less than 1.7%...

  15. Study on Sound Absorption Properties of Coconut Coir Fibre Reinforced Composite with Added Recycled Rubber

    Directory of Open Access Journals (Sweden)

    S. Mahzan

    2010-06-01

    Full Text Available Sound pollutions have become worsen and creating concerns for many peoples. Conventionally, expensive sound absorption materials are employed to control noise disturbances. However, recent developments on natural fibres have created interest for researchers especially for acoustics application purposes. This paper investigates the viability of coconut coir added with recycled rubber to be implemented as sound absorption panel. The composite is constructed at prescribed percentages of fillers and polyurethane as resin. The two-microphone method was applied to obtain the acoustic properties of the samples. The samples were also tested for physical properties such as density and porosity, as well as the microstructures. The results demonstrate good acoustics performances and highlight the potential of the coconut coir reinforced with recycled rubber as the sound absorption panel.

  16. Impact of Throughput in Enhancing the Efficiency of Cognitive Radio Ad Hoc Network - A Study

    Directory of Open Access Journals (Sweden)

    V. Jayaraj

    2013-09-01

    Full Text Available Cognitive Radio Ad Hoc Networks (CRAHNs constitute a viable solution to solve the current problems of inefficiency in the spectrum allocation, and to deploy highly reconfigurable and self-organizing wireless networks. Cognitive Radio (CR devices are envisaged to utilize the spectrum in an opportunistic way by dynamically accessing different licensed portions of the spectrum. However the phenomena of channel fading and primary cum secondary interference in cognitive radio networks does not guarantee application demands to be achieved continuously over time. Availability of limited spectrum and the inadequate spectrum resource usage necessitates a new communication standard to utilize the existing wireless spectrum opportunistically. This paper discusses currently existing mechanism for providing better efficiency by utilizing cognitive network intelligence. The frequencies used are utilized to the maximum extent without any interference. This paper aims in comparing the techniques used for enhancing the throughput in CR.

  17. Value-Added Exchange Rates

    OpenAIRE

    Rudolfs Bems; Robert C. Johnson

    2012-01-01

    This paper updates the conceptual foundations for measuring real effective exchange rates (REERs) to allow for vertical specialization in trade. We derive a value-added REER describing how demand for the value added that a country produces changes as the price of its value added changes relative to competitors. We then compute this index for 42 countries from 1970-2009 using trade measured in value added terms and GDP deflators. There are substantial differences between value-added and conven...

  18. Pathologies in Lovelock AdS Black Branes and AdS/CFT

    CERN Document Server

    Takahashi, Tomohiro

    2011-01-01

    We study the pathologies in AdS black branes in Lovelock theory. More precisely, we examine the conditions that AdS black branes have the naked singularity, the ghost instability and the dynamical instability. From the point of view of the AdS/CFT correspondence, the pathologies in AdS black branes indicate the pathologies in the corresponding CFT. Hence, we need to be careful when we apply AdS/CFT in Lovelock theory to various phenomena such as the shear viscosity to entropy ratio in strongly coupled quantum filed theory.

  19. Recovery of weak factor loadings when adding the mean structure in confirmatory factor analysis: A simulation study

    Directory of Open Access Journals (Sweden)

    Carmen eXiménez

    2016-01-01

    Full Text Available This article extends previous research on the recovery of weak factor loadings in confirmatory factor analysis by exploring the effects of adding the mean structure. This issue has not been examined in previous research. This study is based on the framework of Yung and Bentler (1999 and aims to examine the conditions that affect the recovery of weak factor loadings when the model includes the mean structure, compared to analyzing the covariance structure alone. A simulation study was conducted in which several constraints were defined for one-, two-, and three-factor models. Results show that adding the mean structure improves the recovery of weak factor loadings and reduces the asymptotic variances for the factor loadings, particularly for the models with a smaller number of factors and a small sample size. Therefore, under certain circumstances, modeling the means should be seriously considered for covariance models containing weak factor loadings.

  20. Study on transient beam loading compensation for China ADS proton linac injector II

    Science.gov (United States)

    Gao, Zheng; He, Yuan; Wang, Xian-Wu; Chang, Wei; Zhang, Rui-Feng; Zhu, Zheng-Long; Zhang, Sheng-Hu; Chen, Qi; Powers, Tom

    2016-05-01

    Significant transient beam loading effects were observed during beam commissioning tests of prototype II of the injector for the accelerator driven sub-critical (ADS) system, which took place at the Institute of Modern Physics, Chinese Academy of Sciences, between October and December 2014. During these tests experiments were performed with continuous wave (CW) operation of the cavities with pulsed beam current, and the system was configured to make use of a prototype digital low level radio frequency (LLRF) controller. The system was originally operated in pulsed mode with a simple proportional plus integral and deviation (PID) feedback control algorithm, which was not able to maintain the desired gradient regulation during pulsed 10 mA beam operations. A unique simple transient beam loading compensation method which made use of a combination of proportional and integral (PI) feedback and feedforward control algorithm was implemented in order to significantly reduce the beam induced transient effect in the cavity gradients. The superconducting cavity field variation was reduced to less than 1.7% after turning on this control algorithm. The design and experimental results of this system are presented in this paper. Supported by National Natural Science Foundation of China (91426303, 11525523)

  1. Study of surfactant-added TMAH for applications in DRIE and wet etching-based micromachining

    Science.gov (United States)

    Tang, B.; Shikida, M.; Sato, K.; Pal, P.; Amakawa, H.; Hida, H.; Fukuzawa, K.

    2010-06-01

    In this paper, etching anisotropy is evaluated for a number of different crystallographic orientations of silicon in a 0.1 vol% Triton-X-100 added 25 wt% tetramethylammonium hydroxide (TMAH) solution using a silicon hemisphere. The research is primarily aimed at developing advanced applications of wet etching in microelectromechanical systems (MEMS). The etching process is carried out at different temperatures in the range of 61-81 °C. The etching results of silicon hemisphere and different shapes of three-dimensional structures in {1 0 0}- and {1 1 0}-Si surfaces are analyzed. Significantly important anisotropy, different from a traditional etchant (e.g. pure KOH and TMAH), is investigated to extend the applications of the wet etching process in silicon bulk micromachining. The similar etching behavior of exact and vicinal {1 1 0} and {1 1 1} planes in TMAH + Triton is utilized selectively to remove the scalloping from deep reactive-ion etching (DRIE) etched profiles. The direct application of the present research is demonstrated by fabricating a cylindrical lens with highly smooth etched surface finish. The smoothness of a micro-lens at different locations is measured qualitatively by a scanning electron microscope and quantitatively by an atomic force microscope. The present paper provides a simple and effective fabrication method of the silicon micro-lens for optical MEMS applications.

  2. Emergy evaluation using the calculation software SCALE: case study, added value and potential improvements.

    Science.gov (United States)

    Arbault, Damien; Rugani, Benedetto; Marvuglia, Antonino; Benetto, Enrico; Tiruta-Barna, Ligia

    2014-02-15

    This paper reports the emergy-based evaluation (EME) of the ecological performance of four water treatment plants (WTPs) using three different approaches. The results obtained using the emergy calculation software SCALE (EMESCALE) are compared with those achieved through a conventional emergy evaluation procedure (EMECONV), as well as through the application of the Solar Energy Demand (SED) method. SCALE's results are based on a detailed representation of the chain of technological processes provided by the lifecycle inventory database ecoinvent®. They benefit from a higher level of details in the description of the technological network as compared to the ones calculated with a conventional EME and, unlike the SED results, are computed according to the emergy algebra rules. The analysis delves into the quantitative comparison of unit emergy values (UEVs) for individual technospheric inputs provided by each method, demonstrating the added value of SCALE to enhance reproducibility, accurateness and completeness of an EME. However, SCALE cannot presently include non-technospheric inputs in emergy accounting, like e.g. human labor and ecosystem services. Moreover, SCALE is limited by the approach used to build the dataset of UEVs for natural resources. Recommendations on the scope and accuracy of SCALE-based emergy accounting are suggested for further steps in software development, as well as preliminary quantitative methods to account for ecosystem services and human labor.

  3. Study on Doppler coefficient for metallic fuel fast reactor added hydrogeneous moderator

    Energy Technology Data Exchange (ETDEWEB)

    Hirakawa, Naohiro; Iwasaki, Tomohiko; Tsujimoto, Kazuhumi [Tohoku Univ., Sendai (Japan). Faculty of Engineering; Osugi, Toshitaka; Okajima, Shigeaki; Andoh, Masaki; Nemoto, Tatsuo; Mukaiyama, Takehiko

    1998-01-01

    A series of mock-up experiments for moderator added metallic fast reactor core was carried out at FCA to obtain the experimental verification for improvement of reactivity coefficients. Softened neutron spectrum increases Doppler effect by a factor of 2, and flatter adjoint neutron spectrum decreases Na void effect by a factor of 0.6 when hydrogen to heavy metal atomic number ratio is increased from 0.02 to 0.13. The experimental results are analyzed with SLALOM and CITATION-FBR, which is the standard design code system for a fast reactor at JAERI, and SRAC95 and CITATION-FBR. The present code system gives generally good agreement with the experimental results, especially by the use of the latter, the dependence of the Doppler effect to the hydrogen to fuel element atomic number density ratio is disappeared. Therefore, it looks possible to use the present code system for the conceptual design of a fast reactor system with hydrogeneous materials. (author)

  4. A Study on Contributory Group Key Agreements for Mobile Ad Hoc Networks

    Directory of Open Access Journals (Sweden)

    CH. V. Raghavendran

    2013-04-01

    Full Text Available Wireless networks, in particular Mobile Ad hoc Networks (MANETs have revolutionized the field of networking with increasing number of their commercial and military applications. Security on the other hand, is now an essential requirement for these applications. However, the limitations of the dynamic, infrastructure-less nature of MANETs impose major difficulties in establishing a secure framework suitable for such services. Security for MANETs is a dynamic area of research. Most of the traditional routing protocols proposed for MANETs are focused on routing only not on the security aspects. As in traditional wired networks, wireless networks also require security. Unlike the wired networks, where dedicated routers, servers control the network, in MANETs nodes act both as terminals and also as routers for other nodes. A popular mechanism to satisfy the security requirements is the Group Key Management in which the group key is to be shared by each group communication participant. But to establish and manage the group key efficiently imposes new challenges – especially in infrastructure less MANETs. The basic needs of such networks require that the group key schemes must demonstrate not only high performance but also fault-tolerance.

  5. Performance Comparison Study of Connected Dominating Set Algorithms for Mobile Ad hoc Networks under Different Mobility Models

    Directory of Open Access Journals (Sweden)

    Natarajan Meghanathan

    2013-05-01

    Full Text Available The high-level contribution of this paper is an exhaustive simulation-based comparison study of three categories (density, node id and stability-based of algorithms to determine connected dominating sets (CDS for mobile ad hoc networks and evaluate their performance under two categories (random node mobility and grid-based vehicular ad hoc network of mobility models. The CDS algorithms studied are the maximum density-based (MaxD-CDS, node ID-based (ID-CDS and the minimum velocity-based (MinV-CDS algorithms representing the density, node id and stability categories respectively. The node mobility models used are the Random Waypoint model (representing random node mobility and the City Section and Manhattan mobility models (representing the grid-based vehicular ad hoc networks. The three CDS algorithms under the three mobility models are evaluated with respect to two critical performance metrics: the effective CDS lifetime (calculated taking into consideration the CDS connectivity and absolute CDS lifetime and the CDS node size. Simulations are conducted under a diverse set of conditions representing low, moderate and high network density, coupled with low, moderate and high node mobility scenarios. For each CDS, the paper identifies the mobility model that can be employed to simultaneously maximize the lifetime and minimize the node size with minimal tradeoff. For the two VANET mobility models, the impact of the grid block length on the CDS lifetime and node size is also evaluated.

  6. The value of adding optics to ecosystem models: a case study

    Directory of Open Access Journals (Sweden)

    M. Fujii

    2007-10-01

    Full Text Available Many ecosystem models have been developed to study the ocean's biogeochemical properties, but most of these models use simple formulations to describe light penetration and spectral quality. Here, an optical model is coupled with a previously published ecosystem model that explicitly represents two phytoplankton (picoplankton and diatoms and two zooplankton functional groups, as well as multiple nutrients and detritus. Surface ocean color fields and subsurface light fields are calculated by coupling the ecosystem model with an optical model that relates biogeochemical standing stocks with inherent optical properties (absorption, scattering; this provides input to a commercially available radiative transfer model (Ecolight. We apply this bio-optical model to the equatorial Pacific upwelling region, and find the model to be capable of reproducing many measured optical properties and key biogeochemical processes in this region. Our model results suggest that non-algal particles largely contribute to the total scattering or attenuation (>50% at 660 nm but have a much smaller contribution to particulate absorption (<20% at 440 nm, while picoplankton dominate the total phytoplankton absorption (>95% at 440 nm. These results are consistent with the field observations. In order to achieve such good agreement between data and model results, however, key model parameters, for which no field data are available, have to be constrained. Sensitivity analysis of the model results to optical parameters reveals a significant role played by colored dissolved organic matter through its influence on the quantity and quality of the ambient light. Coupling explicit optics to an ecosystem model provides advantages in generating: (1 a more accurate subsurface light-field, which is important for light sensitive biogeochemical processes such as photosynthesis and photo-oxidation, (2 additional constraints on model parameters that help to reduce uncertainties in

  7. Adding Salt to Meals as a Risk Factor of Type 2 Diabetes Mellitus: A Case–Control Study

    Directory of Open Access Journals (Sweden)

    Lina Radzeviciene

    2017-01-01

    Full Text Available Objective: Type 2 diabetes mellitus (T2DM is thought to arise from the complex interplay between genetic and environmental factors. It is important to identify modifiable risk factors that may help to reduce the risk of diabetes. Data on salt intake and the risk of type 2 diabetes are limited. The aim of this study was to assess the relationship between adding salt to prepared meals and the risk of type 2 diabetes. Methods: In a case–control study, we included 234 cases, all of whom were patients aged 35–86 years with a newly confirmed diagnosis of T2DM, and 468 controls that were free of the disease. Cases and controls (ratio 1:2 were matched by gender and age (±5 years. A questionnaire was used to collect information on possible risk factors for diabetes. Adding salt to prepared meals was assessed according to: Never, when there was not enough, or almost every time without tasting. The odds ratios (OR, and 95% confidence intervals (CI for type 2 diabetes was calculated using a conditional logistic regression. Results: The cases had a higher body mass index and a significantly lower education level compared to the controls. Variables such as waist circumference, body mass index, eating speed, smoking, family history of diabetes, arterial hypertension, plasma triglycerides, educational level, occupational status, morning exercise, marital status, daily urine sodium excretion, and daily energy intake were retained in the models as confounders. After adjusting for possible confounders, an approximately two-fold increased risk of type 2 diabetes was determined in subjects who add salt to prepared meals when “it is not enough” or “almost every time without tasting” (1.82; 95% CI 1.19–2.78; p = 0.006 compared with never adding salt. Conclusion: Presented data suggest the possible relationship between additional adding of salt to prepared meals and an increased risk of type 2 diabetes.

  8. Catalytic domain of plasmid pAD1 relaxase TraX defines a group of relaxases related to restriction endonucleases.

    Science.gov (United States)

    Francia, María Victoria; Clewell, Don B; de la Cruz, Fernando; Moncalián, Gabriel

    2013-08-13

    Plasmid pAD1 is a 60-kb conjugative element commonly found in clinical isolates of Enterococcus faecalis. The relaxase TraX and the primary origin of transfer oriT2 are located close to each other and have been shown to be essential for conjugation. The oriT2 site contains a large inverted repeat (where the nic site is located) adjacent to a series of short direct repeats. TraX does not show any of the typical relaxase sequence motifs but is the prototype of a unique family of relaxases (MOBC). The present study focuses on the genetic, biochemical, and structural analysis of TraX, whose 3D structure could be predicted by protein threading. The structure consists of two domains: (i) an N-terminal domain sharing the topology of the DNA binding domain of the MarR family of transcriptional regulators and (ii) a C-terminal catalytic domain related to the PD-(D/E)XK family of restriction endonucleases. Alignment of MOBC relaxase amino acid sequences pointed to several conserved polar amino acid residues (E28, D152, E170, E172, K176, R180, Y181, and Y203) that were mutated to alanine. Functional analysis of these mutants (in vivo DNA transfer and cleavage assays) revealed the importance of these residues for relaxase activity and suggests Y181 as a potential catalytic residue similarly to His-hydrophobe-His relaxases. We also show that TraX binds specifically to dsDNA containing the oriT2 direct repeat sequences, confirming their role in transfer specificity. The results provide insights into the catalytic mechanism of MOBC relaxases, which differs radically from that of His-hydrophobe-His relaxases.

  9. An $xp$ model on $AdS_2$ spacetime

    CERN Document Server

    Molina-Vilaplana, Javier

    2013-01-01

    In this paper we formulate the $xp$ model on the AdS$_2$ spacetime. We find that the spectrum of the Hamiltonian has positive and negative eigenvalues, equal in magnitude, given by a harmonic oscillator with a zero point energy parameterized by the AdS radius, measured in units of a fundamental length of the model. We also construct the generators of the isometry group SO(2,1) of the AdS$_2$ spacetime, and discuss the relation with conformal quantum mechanics.

  10. An AdS Crunch in Supergravity

    Science.gov (United States)

    Hertog, Thomas

    2004-12-01

    We review some properties of N=8 gauged supergravity in four dimensions with modified, but AdS invariant boundary conditions on the m2 = -2 scalars. There is a one-parameter class of asymptotic conditions on these fields and the metric components, for which the full AdS symmetry group is preserved. The generators of the asymptotic symmetries are finite, but acquire a contribution from the scalar fields. For a large class of such boundary conditions, we find there exist black holes with scalar hair that are specified by a single conserved charge. Since Schwarschild-AdS is a solution too for all boundary conditions, this provides an example of black hole non-uniqueness. We also show there exist solutions where smooth initial data evolve to a big crunch singularity. This opens up the possibility of using the dual conformal field theory to obtain a fully quantum description of the cosmological singularity, and we report on a preliminary study of this.

  11. TRAFFIC CONTROLLED-DEDICATED SHORT RANGE COMMUNICATION: A SECURE COMMUNICATION USING TRAFFIC CONTROLLED DEDICATED SHORT RANGE COMMUNICATION MODEL IN VEHICULAR AD HOC NETWORKS FOR SAFETY RELATED SERVICES

    Directory of Open Access Journals (Sweden)

    K. Chandramohan

    2014-01-01

    Full Text Available To increase the road safety and secure communication among the vehicles in the network environment, Dedicated Short Range Communication (DSRC is followed. Nowadays, research over DSRC is dramatically increased for enhancing the road safety applications. The main task of DSRC is to protect the vehicles by communicating the warning message regarding the vehicle changing conditions, traffic occurrence and dangers over the road in the network. So, it is necessary to maintain the accurate communication timely with high reliability by implementing the appropriate protocol. In the literature there are several methods which provided specifications defined in the physical layer and the Medium Access Control (MAC layer. In those methods, current IEEE 802.11p MAC is not able to provide predictable Quality of Service (QoS for high-priority safety services. Motivated by the fact that the existing work provided three levels of safety-related broadcast services, but did not focus on current traffic load conditions, in this study, we plan to present Traffic Controlled DSRC (TC-DSRC model to analyze and categorize the traffic patterns in the vehicular communication for safety related application. A new algorithm is presented to evaluate the process of traffic controlled DSRC model for secure communication in VANET. The dedicated short range communication broadcast of messages is sent to all the vehicles at a specific instance for defined radius on the traffic zone. Multiple traffic load conditions are categorically stated to handle the vehicular safety with quick response time. Integrating these two performance metrics (i.e., quick response time and security, by using the proposed algorithm, the traffic patterns are categorized for communication between vehicles to provide the safety measure. In addition, our proposed scheme with the categorization using traffic patterns improves the network performance by deriving a specific pattern. Compared with the recent

  12. Planetary Aeronomy and Related Studies

    Science.gov (United States)

    Hunten, D. M.; Bougher, S. W.; Sprague, A. L.

    1997-01-01

    Mercury atmosphere - Sprague and Hunten, in collaboration with Katharina Lodders of Washington University, proposed, mainly on cosmochemical grounds, that S atoms are an important constituent of the atmosphere (30 times more abundant than sodium). This paper has appeared in Icarus. We also suggest that condensed sulfur is an excellent candidate for the radar-bright polar caps, more plausible than water ice because the latter is only barely stable even in permanently-shadowed craters. The best prospect for detection of the vapor is through its resonance lines, a triplet near 1814 A. Mercury is too close to the Sun to be observed by any existing space telescope, but there is some prospect that the search could be made from a Shuttle-based spectrograph such as Lyle Broadfoot's USTAR. Sprague and Hunten have completed an elaborate data analysis of over 100 measurements of the Na D lines, obtained with the 61-inch telescope and our echelle spectrograph. Full account has been taken of the radiative-transfer problem that arises because the Na atmosphere is not optically thin. The output of this code is used in another program that makes an elaborate inverse interpolation in two angles and optical depth and computes the effect of the seeing (always bad for Mercury). The seeing is determined by fitting cuts across a computed image to part of the spectrum adjacent to the sodium lines, and typically ranges from slightly less than 4 arcsec to worse than 6 (diameter at l/e of a Gaussian). The final result is a list of Na abundances, with some information on spatial distribution. One particularly interesting result of further analysis is a strong abundance maximum in the morning relative to the afternoon, confirming an earlier result for potassium, based on much fewer measurements. The analysis are completed during the extension of the present grant. This work depends heavily on the Hapke parameters used to estimate the reflectance of Mercury's surface. The paper by Domingue et

  13. Entanglement Temperature and Perturbed AdS$_3$ Geometry

    CERN Document Server

    Levine, Gregory

    2015-01-01

    In analogy to the first law of thermodynamics, the increase in entanglement entropy $\\delta S$ of a conformal field theory (CFT) is proportional to the increase in energy, $\\delta E$, of the subsystem divided by an effective entanglement temperature, $T_E$. Extending this analogy, we study entanglement entropy when the subsystem is perturbed by applying an external field, expressed as a coupling to a local marginal operator in the CFT. We show that the resulting entropy change is associated with a change in the entanglement temperature itself, leading to an equation analogous to the Clausius relation. Using AdS/CFT duality we develop a relationship between a perturbation in the local entanglement temperature, $\\delta T_E(x)$ of the CFT and the perturbation of the bulk AdS metric. Using the AdS$_3$ minimal surface as a probe, we can construct bulk metric perturbations from an exact numerical computation of the entanglement temperature in a two dimensional $c=1$ boundary theory deformed by a marginal perturbati...

  14. Exposure to movie smoking, antismoking ads and smoking intensity: an experimental study with a factorial design

    NARCIS (Netherlands)

    Harakeh, Z.; Engels, R.C.M.E.; Vohs, K.; van Baaren, R.B.; Sargent, J.

    2010-01-01

    Background This study examines whether smoking portrayal in movies or antismoking advertisements affect smoking intensity among young adults. Methods We conducted an experimental study in which 84 smokers were randomly assigned using a two (no-smoking versus smoking portrayal in the movie) by three

  15. Ending on a high note: adding a better end to effortful study.

    Science.gov (United States)

    Finn, Bridgid

    2010-11-01

    Remembered utility is the retrospective evaluation about the pleasure and pain associated with a past experience. It has been shown to influence prospective choices about whether to repeat or to avoid similar situations in the future (D. Kahneman 2000; D. Kahneman, D. L. Fredrickson, C. A. Schreiber, & D. A. Redelmeier, 1993). Evaluations about our hedonic past often disregard the duration of the experience and are influenced more by the peak and the final levels of discomfort (B. L. Fredrickson & D. Kahneman, 1993). Two experiments explored the remembered discomfort of an effortful learning experience and the influence of this evaluation on prospective study choices. The design of the studies mimicked D. Kahneman et al.'s (1993) cold-pressor study, but used an exceptionally challenging learning experience in place of the painful experience of submerging one's hand in ice water. An extremely effortful study episode extended by a more moderate interval was preferred to a shorter, unextended interval, despite better test performance following the shorter interval. Future study choices reflected this preference. These findings suggest that the act of acquiring knowledge has value in the learning process.

  16. A study on the preparation of value-added products from the nonmetallic minerals

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-12-01

    This report consists of 2 subjects. 1) A study on manufacturing technology of materials for fine chemical industry use (muscovite, sericite): For the technical development on utilization of unused mineral resources, the study was carried out on the highly purification and mineral processing of domestic sericite and muscovite. This study was also carried out to make the functional materials for the use of fine chemical industry. Scope and content of study is the high purification and the surface treatment of fine particles of sericite and muscovite. 2) Studies on manufacturing technology of materials for fine chemical and electronic industry use: Fine natural crystalline graphite which is used as a source material of a high electrically conductive film and an addition of advanced high functional solid lubricant. For use high electrically conductive film and advanced high functional solid lubricant, add new and advanced high functional properties to fine graphite powder through surface modification with gas and organic materials. (author). 71 refs., 45 tabs., 84 figs.

  17. HEFCE's People Management Self-Assessment Tool: Ticking Boxes or Adding Value? A Case Study

    Science.gov (United States)

    McDonald, Claire

    2009-01-01

    This article examines one specific organisational development tool in depth and uses a case study to investigate whether using the tool is more than a tick-box exercise and really can add value and help organisations to develop and improve. The People Management Self-Assessment Tool (SAT) is used to examine higher education institutions' (HEIs)…

  18. Adding a Design Perspective to Study Learning Environments in Higher Professional Education

    Science.gov (United States)

    Zitter, Ilya; De Bruijn, Elly; Simons, P. Robert Jan; Cate, Th. J. Ten

    2011-01-01

    How to design learning environments leading to learning-, thinking, collaboration- and regulation skills which can be applied to transferable, knowledge oriented learning outcomes is still controversial. We studied the designs of learning environments in innovative higher professional education more closely. To characterize learning environments…

  19. Adding Qualitative and Mixed Methods Research to Health Intervention Studies: Interacting With Differences.

    Science.gov (United States)

    Johnson, R Burke; Schoonenboom, Judith

    2016-04-01

    The purpose of this article is to explain how to improve intervention designs, such as randomized controlled trials (RCTs), in health science research using a process philosophy and theory known as dialectical pluralism (DP). DP views reality as plural and uses dialectical, dialogical, and hermeneutical approaches to knowledge construction. Using DP and its "both/and" logic, and its attempt to produce new creative syntheses, researchers on heterogeneous teams can better dialogue with qualitative and mixed methods approaches, concepts, paradigms, methodologies, and methods to improve their intervention research studies. The concept of reflexivity is utilized but is expanded when it is a component of DP. Examples of strategies for identifying, inviting, and creating divergence and integrative strategies for producing strong mixed methods intervention studies are provided and illustrated using real-life examples.

  20. Protein expression and preparation of polydonal antibody of AD-004 and study on its expression in the adrenal and testis

    Institute of Scientific and Technical Information of China (English)

    乔洁

    2006-01-01

    Objective To prepare rabbit antibody against mouse AD-004 by AD-004 expressed in the prokaryotic expression system and to identify its distribution in the testis and adrenal. Methods The full-length cDNA of mouse AD-004 was cloned into PET28 plasmid, and the protein was induced in E. coli BL21 bacteria by adding IPTG and then purified by Ni2+ -NTA column. The purified protein was used as an immunogene to prepare polyclonal

  1. Ad libitum fluid intake leads to no leg swelling in male Ironman triathletes – an observational field study

    Science.gov (United States)

    2012-01-01

    Background An association between fluid intake and limb swelling has been described for 100-km ultra-marathoners. We investigated a potential development of peripheral oedemata in Ironman triathletes competing over 3.8 km swimming, 180 km cycling and 42.2 km running. Methods In 15 male Ironman triathletes, fluid intake, changes in body mass, fat mass, skeletal muscle mass, limb volumes and skinfold thickness were measured. Changes in renal function, parameters of skeletal muscle damage, hematologic parameters and osmolality in both serum and urine were determined. Skinfold thicknesses at hands and feet were measured using LIPOMETER® and changes of limb volumes were measured using plethysmography. Results The athletes consumed a total of 8.6 ± 4.4 L of fluids, equal to 0.79 ± 0.43 L/h. Body mass, skeletal muscle mass and the volume of the lower leg decreased (p 0.05). The decrease in skeletal muscle mass was associated with the decrease in body mass (p 0.05). Haemoglobin, haematocrit and serum sodium remained unchanged (p >0.05). Osmolality in serum and urine increased (p <0.05). The change in body mass was related to post-race serum sodium concentration ([Na+]) (r = −0.52, p <0.05) and post-race serum osmolality (r = −0.60, p <0.05). Conclusions In these Ironman triathletes, ad libitum fluid intake maintained plasma [Na+] and plasma osmolality and led to no peripheral oedemata. The volume of the lower leg decreased and the decrease was unrelated to fluid intake. Future studies may investigate ultra-triathletes competing in a Triple Iron triathlon over 11.4 km swimming, 540 km cycling and 126.6 km running to find an association between fluid intake and the development of peripheral oedemata. PMID:22937792

  2. Adding value through accelerator mass spectrometry-enabled first in human studies.

    Science.gov (United States)

    Seymour, Mark A

    2016-12-01

    Accelerator mass spectrometry (AMS) is an ultra-sensitive technique for the analysis of radiocarbon. It is applicable to bioanalysis of any (14) C-labelled analyte and any sample type. The increasing body of data generated using LC+AMS indicates that the methodology is robust and reliable, and capable of meeting the same validation criteria as conventional bioanalytical techniques. Because it is a tracer technique, AMS is capable of discriminating between an administered radiolabelled dose and endogenous compound or non-radiolabelled compound administered separately. This paper discusses how it can be used to enhance the design of first in human (FIH) clinical studies and generate significant additional data, including: fundamental pharmacokinetics (CL and V), absolute bioavailability, mass balance, routes and rates of excretion, metabolic fate (including first-pass metabolism, identification of biliary metabolites and quantitative data to address metabolite safety testing issues), and tissue disposition of parent compound and metabolites. Because the (14) C-labelled microtracer dose is administered at the same time as a pharmacologically relevant non-radiolabelled dose, there is no concern about dose-linearity. However the mass of the microtracer dose itself is negligible and therefore does not affect the outcome of the FIH study. The addition of microtracer doses to a FIH study typically requires little additional expense, apart from the AMS analytics, making the approach cost-effective. It can also save significant time, compared to conventional approaches, and, by providing reliable human in vivo data as early as possible, prevent unnecessary expenditure later in drug development.

  3. A comparative study of MONTEBURNS and MCNPX 2.6.0 codes in ADS simulations

    Energy Technology Data Exchange (ETDEWEB)

    Barros, Graiciany P.; Pereira, Claubia; Veloso, Maria A.F.; Velasquez, Carlos E.; Costa, Antonella L., E-mail: gbarros@ufmg.br, E-mail: claubia@nuclear.ufmg.br [Universidade Federal de Minas Gerais (UFMG), Belo Horizonte, MG (Brazil). Dept. de Engenharia Nuclear

    2013-07-01

    The possible use of the MONTEBURNS and MCNPX 2.6.0 codes in Accelerator-driven systems (ADSs) simulations for fuel evolution description is discussed. ADSs are investigated for fuel breeding and long-lived fission product transmutation so simulations of fuel evolution have a great relevance. The burnup/depletion capability is present in both studied codes. MONTEBURNS code links Monte Carlo N-Particle Transport Code (MCNP) to the radioactive decay burnup code ORIGEN2, whereas MCNPX depletion/ burnup capability is a linked process involving steady-state flux calculations by MCNPX and nuclide depletion calculations by CINDER90. A lead-cooled accelerator-driven system fueled with thorium was simulated and the results obtained using MONTEBURNS code and the results from MCNPX 2.6.0 code were compared. The system criticality and the variation of the actinide inventory during the burnup were evaluated and the results indicate a similar behavior between the results of each code. (author)

  4. Lattice and string worldsheet in AdS/CFT: a numerical study

    CERN Document Server

    Forini, Valentina; Bianchi, Marco S; Leder, Björn; Vescovi, Edoardo

    2016-01-01

    We consider a possible discretization for the gauge-fixed Green-Schwarz (two-dimensional) sigma-model action for the Type IIB superstring and use it for measuring the cusp anomalous dimension of planar $\\mathcal{N}=4$ SYM as derived from string theory. We perform lattice simulations employing a Rational Hybrid Monte Carlo (RHMC) algorithm and a Wilson-like fermion discretization. In this preliminary study, we compare our results with the expected behavior for very large values of $g=\\frac{\\sqrt{\\lambda}}{4\\pi}$, which is the perturbative regime of the sigma-model, and find a qualitative agreement at finite lattice spacing. For smaller $g$ the continuum limit is obstructed by a divergence. We also detect a phase in the fermion determinant, whose origin we explain, which for small $g$ leads to a sign problem not treatable via standard reweigthing. Results presented here are discussed thoroughly in~\\cite{toappear}.

  5. AN EXPERIMENTAL STUDY ON A VAPOR COMPRESSION REFRIGERATION CYCLE BY ADDING INTERNAL HEAT EXCHANGER

    Directory of Open Access Journals (Sweden)

    Muhammad Asmail Eleiwi

    2013-05-01

    Full Text Available Thispaper presents practical study to improve the indication COP of a vaporcompression refrigeration cycle in instrumented automobile air conditioner bydesigning internal heat exchanger and installing it in the vapor compressionrefrigeration cycle.  Two cases of  vapor compression refrigeration cycle were takenin this paper:  the first case is thatthe vapor compression refrigeration cycle without internal heat exchanger andin  the second case the vapor compressionrefrigeration cycle with heat exchanger ; in these two cases, the temperatureat each point of  a vapor compressionrefrigeration cycle, the low and the high pressure ,the indoor temperature andthe outdoor temperature were measured at each time at compressor speed 1450 rpmand 2900 rpm for each blower speed 1, blower speed 2 and blower speed 3.Therefrigerant fluid was used in the vapor compression refrigeration cycle withoutIHE and with IHE is R134a..

  6. The Added Value of Eye-tracking in Diagnosing Dyscalculia: A Case Study

    Directory of Open Access Journals (Sweden)

    Sietske eVan Viersen

    2013-10-01

    Full Text Available The present study compared eye movements and performance of a nine-year-old girl with Developmental Dyscalculia (DD on a series of number line tasks to those of a group of typically developing (TD children (n = 10, in order to answer the question whether eye-tracking data from number line estimation tasks can be a useful tool to discriminate between TD children and children with a number processing deficit. Quantitative results indicated that the child with dyscalculia performed worse on all symbolic number line tasks compared to the control group, indicated by a low linear fit (R2 and a low accuracy measured by mean percent absolute error. In contrast to the control group, her magnitude representations seemed to be better represented by a logarithmic than a linear fit. Furthermore, qualitative analyses on the data of the child with dyscalculia revealed more unidentifiable fixation patterns in the processing of multi-digit numbers and more dysfunctional estimation strategy use in one third of the estimation trials as opposed to approximately 10% in the control group. In line with her dyscalculia diagnosis, these results confirm the difficulties with spatially representing and manipulating numerosities on a number line, resulting in inflexible and inadequate estimation or processing strategies. It can be concluded from this case study that eye-tracking data can be used to discern different number processing and estimation strategies in TD children and children with a number processing deficit. Hence, eye-tracking data in combination with number line estimation tasks might be a valuable and promising addition to current diagnostic measures.

  7. The added value of eye-tracking in diagnosing dyscalculia: a case study.

    Science.gov (United States)

    van Viersen, Sietske; Slot, Esther M; Kroesbergen, Evelyn H; Van't Noordende, Jaccoline E; Leseman, Paul P M

    2013-01-01

    The present study compared eye movements and performance of a 9-year-old girl with Developmental Dyscalculia (DD) on a series of number line tasks to those of a group of typically developing (TD) children (n = 10), in order to answer the question whether eye-tracking data from number line estimation tasks can be a useful tool to discriminate between TD children and children with a number processing deficit. Quantitative results indicated that the child with dyscalculia performed worse on all symbolic number line tasks compared to the control group, indicated by a low linear fit (R (2)) and a low accuracy measured by mean percent absolute error. In contrast to the control group, her magnitude representations seemed to be better represented by a logarithmic than a linear fit. Furthermore, qualitative analyses on the data of the child with dyscalculia revealed more unidentifiable fixation patterns in the processing of multi-digit numbers and more dysfunctional estimation strategy use in one third of the estimation trials as opposed to ~10% in the control group. In line with her dyscalculia diagnosis, these results confirm the difficulties with spatially representing and manipulating numerosities on a number line, resulting in inflexible and inadequate estimation or processing strategies. It can be concluded from this case study that eye-tracking data can be used to discern different number processing and estimation strategies in TD children and children with a number processing deficit. Hence, eye-tracking data in combination with number line estimation tasks might be a valuable and promising addition to current diagnostic measures.

  8. Association of ADH4 genetic variants with alcohol dependence risk and related phenotypes: results from a larger multicenter association study.

    Science.gov (United States)

    Preuss, Ulrich W; Ridinger, Monika; Rujescu, Dan; Samochowiec, Jerzy; Fehr, Christoph; Wurst, Friedrich M; Koller, Gabriele; Bondy, Brigitta; Wodarz, Norbert; Debniak, Tadeusz; Grzywacz, Anna; Soyka, Michael; Zill, Peter

    2011-04-01

    Genetic variants of the alcohol-metabolizing enzyme ADH4, located on chromosome 4q22-4q23, have been related to alcohol dependence (AD) risk in previous research. The aim of this association study in a large multicenter sample of alcohol-dependent individuals and controls is to confirm ADH4 single nucleotide polymorphism (SNP) and haplotype association with AD and relevant related phenotypes. One thousand, six hundred and twenty-two (1622) inpatient subjects and 1469 control subjects with DSM-IV. AD from four addiction treatment centres were included. Characteristics of AD and related phenotypes including alcohol withdrawal, Cloninger's type I and II and first ages of drinking, regular drinking and AD onset were obtained using standardized structured interviews. After subjects were genotyped for 2 ADH4 polymorphisms, single SNP case-control and haplotype analyses were conducted. Both variants--rs1800759 and rs1042364--and the A-A and C-G haplotypes were significantly related to AD across samples. Furthermore, associations with AD-related phenotypes and subtypes revealed a potential protective influence of this haplotype. This study confirms the significant relationship of ADH4 variants with AD and related phenotypes. While the rs1800759 and rs1042364 A-A haplotype had a potential protective influence on the risk for several AD-related phenotypes, this effect is rather small compared to functional variants of other alcohol or acetaldehyde-metabolizing enzymes like ALDH2*2 or ADH1B*2.

  9. A study on development of value added technology of pyrophyllite and dickite

    Energy Technology Data Exchange (ETDEWEB)

    Cho, Keon-Joon; Choi, Yeon-Ho; Kim, Sang-Bae; Jeon, Ho-Seok; Cho, Sung-Baek [Korea Institute of Geology Mining and Materials, Taejon (Korea, Republic of)

    1997-12-01

    Pyrophyllite and dickite have being utilized as refractories, ceramics, cement, fiber glass, paper, rubber, paints etc.. However, there are not any domestic companies to produce fillers of pyrophyllite and dickite for plastic and rubber. Moreover, several kinds of fillers are imported every year with expensive price for plastic and rubber filler. This study has purpose to develop manufacturing technologies to produce fillers for plastic and rubber of pyrophyllite and dickite. The chemical and mineralogical properties of samples, the optimum grinding condition and device for producing plastic fillers and development of technology of improvement in whiteness, and the optimum synthesis condition of zeolite Y are the scopes and contents of the study. Pyrophyllite samples are taken from Bunam. Principal composed minerals are pyrophyllite, quartz and dickite, having chemical components of 9.2% Al{sub 2}O{sub 3}, 74.8% SiO{sub 2}, and 0.1% Fe{sub 2}O{sub 3}, respectively. Dickite sample is taken from Bugok, consists of dickite and quartz having 37.7% Al{sub 2}O{sub 3}, 47.8% SiO{sub 2} and 0.04% Fe{sub 2}O{sub 3}. Efficiency of the vibrating mill proved to be greater than ball mill compare with median size. The whiteness of sample increased with roasting temperature. In grinding a Bunam and Bugok sample by vibrating mill for 180 minute, median particle size is 3.06{mu}m and 2.85{mu}m, respectively. The structure water dehydration temperature is about 600 deg.C and mullite is presented around 850 deg.C for dickite, and the whiteness increased with roasting temperature. The whiteness of Bunam and Bugok sample ground by vibrating mill for 180 minute and roasted for 60 minutes at 900 deg.C is 96.5, 98, respectively. The mole ratio of SiO{sub 2}/Al{sub 2}O{sub 3} is important factor for synthesis of zeolite Y, crystallinity is 56 at SiO{sub 2}/Al{sub 2}O{sub 3} mole ratio is 13. Reaction time also important factor, crystallinity is 52 at SiO{sub 2}/Al{sub 2}O{sub 3} mole ratio

  10. Th and U fuel photofission study by NTD for AD-MSR subcritical assembly

    Energy Technology Data Exchange (ETDEWEB)

    Sajo-Bohus, Laszlo; Greaves, Eduardo D.; Barros, Haydn; Pino, Felix; Barrera, Maria T.; Farina, Fulvio [Universidad Simón Bolívar, Nuclear Physics Laboratory, Apdo 89000, Caracas 1080A (Venezuela, Bolivarian Republic of); Davila, Jesus [Física Médica C. A. and Universidad Central de Venezuela, Caracas (Venezuela, Bolivarian Republic of)

    2015-07-23

    During the last decade a considerable effort has been devoted for developing energy generating systems based on advanced nuclear technology within the design concepts of GEN-IV. Thorium base fuel systems such as accelerator driven nuclear reactors are one of the often mentioned attractive and affordable options. Several radiotherapy linear accelerators are on the market and due to their reliability, they could be employed as drivers for subcritical liquid fuel assemblies. Bremsstrahlung photons with energies above 5.5MeV, induce (γ,n) and (e,e’n) reactions in the W-target. Resulting gamma radiation and photo or fission neutrons may be absorbed in target materials such as thorium and uranium isotopes to induce sustained fission or nuclear transmutation in waste radioactive materials. Relevant photo driven and photo-fission reaction cross sections are important for actinides {sup 232}Th, {sup 238}U and {sup 237}Np in the radiotherapy machines energy range of 10-20 MV. In this study we employ passive nuclear track detectors (NTD) to determine fission rates and neutron production rates with the aim to establish the feasibility for gamma and photo-neutron driven subcritical assemblies. To cope with these objectives a 20 MV radiotherapy machine has been employed with a mixed fuel target. Results will support further development for a subcritical assembly employing a thorium containing liquid fuel. It is expected that acquired technological knowledge will contribute to the Venezuelan nuclear energy program.

  11. Studying the Effects of Adding Silica Sand Nanoparticles on Epoxy Based Composites

    Directory of Open Access Journals (Sweden)

    Tahir Ahmad

    2013-01-01

    Full Text Available The research about the preparation of submicron inorganic particles, once conducted in the past decade, is now leading to prepare polymer matrix composite (PMC reinforced with nanofillers. The objective of present research is to study the modified effects of reinforcement dispersion of nanoparticle silica in epoxy resin on the physical properties, mechanical and thermal behaviour, and the microstructure of resultant composites. Stirrer mixing associated with manual mixing of silica sand nanoparticles (developed in our earlier research (Ahmad and Mamat, 2012 into epoxy was followed by curing being the adopted technique to develop the subject nanocomposites. Experimental values showed that 15 wt.% addition of silica sand nanoparticles improves Young’s modulus of the composites; however, a reduction in tensile strength was also observed. Number of holes and cavities produced due to improper mixing turn out to be the main cause of effected mechanical properties. Addition of silica sand nanoparticles causes a reduction in degree of crystallinity of the nanocomposites as being observed in differential scanning calorimetry (DSC analysis.

  12. Th and U fuel photofission study by NTD for AD-MSR subcritical assembly

    Science.gov (United States)

    Sajo-Bohus, Laszlo; Greaves, Eduardo D.; Davila, Jesus; Barros, Haydn; Pino, Felix; Barrera, Maria T.; Farina, Fulvio

    2015-07-01

    During the last decade a considerable effort has been devoted for developing energy generating systems based on advanced nuclear technology within the design concepts of GEN-IV. Thorium base fuel systems such as accelerator driven nuclear reactors are one of the often mentioned attractive and affordable options. Several radiotherapy linear accelerators are on the market and due to their reliability, they could be employed as drivers for subcritical liquid fuel assemblies. Bremsstrahlung photons with energies above 5.5MeV, induce (γ,n) and (e,e'n) reactions in the W-target. Resulting gamma radiation and photo or fission neutrons may be absorbed in target materials such as thorium and uranium isotopes to induce sustained fission or nuclear transmutation in waste radioactive materials. Relevant photo driven and photo-fission reaction cross sections are important for actinides 232Th, 238U and 237Np in the radiotherapy machines energy range of 10-20 MV. In this study we employ passive nuclear track detectors (NTD) to determine fission rates and neutron production rates with the aim to establish the feasibility for gamma and photo-neutron driven subcritical assemblies. To cope with these objectives a 20 MV radiotherapy machine has been employed with a mixed fuel target. Results will support further development for a subcritical assembly employing a thorium containing liquid fuel. It is expected that acquired technological knowledge will contribute to the Venezuelan nuclear energy program.

  13. Nuclear data requirements for the ADS conceptual design EFIT: Uncertainty and sensitivity study

    Energy Technology Data Exchange (ETDEWEB)

    Garcia-Herranz, N., E-mail: nuria@din.upm.e [Departamento de Ingenieria Nuclear, Universidad Politecnica de Madrid (Spain); Instituto de Fusion Nuclear, Universidad Politecnica de Madrid (Spain); Cabellos, O. [Departamento de Ingenieria Nuclear, Universidad Politecnica de Madrid (Spain); Instituto de Fusion Nuclear, Universidad Politecnica de Madrid (Spain); Alvarez-Velarde, F. [CIEMAT (Spain); Sanz, J. [Instituto de Fusion Nuclear, Universidad Politecnica de Madrid (Spain); Departamento de Ingenieria Energetica, UNED (Spain); Gonzalez-Romero, E.M. [CIEMAT (Spain); Juan, J. [Laboratorio de Estadistica, Universidad Politecnica de Madrid (Spain)

    2010-11-15

    In this paper, we assess the impact of activation cross-section uncertainties on relevant fuel cycle parameters for a conceptual design of a modular European Facility for Industrial Transmutation (EFIT) with a 'double strata' fuel cycle. Next, the nuclear data requirements are evaluated so that the parameters can meet the assigned design target accuracies. Different discharge burn-up levels are considered: a low burn-up, corresponding to the equilibrium cycle, and a high burn-up level, simulating the effects on the fuel of the multi-recycling scenario. In order to perform this study, we propose a methodology in two steps. Firstly, we compute the uncertainties on the system parameters by using a Monte Carlo simulation, as it is considered the most reliable approach to address this problem. Secondly, the analysis of the results is performed by a sensitivity technique, in order to identify the relevant reaction channels and prioritize the data improvement needs. Cross-section uncertainties are taken from the EAF-2007/UN library since it includes data for all the actinides potentially present in the irradiated fuel. Relevant uncertainties in some of the fuel cycle parameters have been obtained, and we conclude with recommendations for future nuclear data measurement programs, beyond the specific results obtained with the present nuclear data files and the limited available covariance information. A comparison with the uncertainty and accuracy analysis recently published by the WPEC-Subgroup26 of the OECD using BOLNA covariance matrices is performed. Despite the differences in the transmuter reactor used for the analysis, some conclusions obtained by Subgroup26 are qualitatively corroborated, and improvements for additional cross sections are suggested.

  14. Rigid Holography and Six-Dimensional N=(2,0) Theories on AdS_5 times S^1

    CERN Document Server

    Aharony, Ofer; Rey, Soo-Jong

    2015-01-01

    Field theories on anti-de Sitter (AdS) space can be studied by realizing them as low-energy limits of AdS vacua of string/M theory. In an appropriate limit, the field theories decouple from the rest of string/M theory. Since these vacua are dual to conformal field theories (CFTs), this relates some of the observables of these field theories on AdS to a subsector of the dual CFTs. We exemplify this `rigid holography' by studying in detail the 6d N=(2,0) A_{K-1} superconformal field theory (SCFT) on AdS_5xS^1, with equal radii for AdS_5 and for S^1. We choose specific boundary conditions preserving sixteen supercharges that arise when this theory is embedded into Type IIB string theory on AdS_5xS^5/Z_K. On R^{4,1}xS^1, this 6d theory has a 5(K-1)-dimensional moduli space, with unbroken 5d SU(K) gauge symmetry at (and only at) the origin. On AdS_5xS^1, the theory has a 2(K-1)-dimensional `moduli space' of supersymmetric configurations. We argue that in this case the SU(K) gauge symmetry is unbroken everywhere in...

  15. Bioenergetic flux, mitochondrial mass and mitochondrial morphology dynamics in AD and MCI cybrid cell lines

    OpenAIRE

    Silva, Diana F.; Selfridge, J. Eva; Lu, Jianghua; E, Lezi; Roy, Nairita; Hutfles, Lewis; Burns, Jeffrey M.; Michaelis, Elias K.; Yan, Shidu; Cardoso, Sandra M.; Swerdlow, Russell H.

    2013-01-01

    Bioenergetic dysfunction occurs in Alzheimer's disease (AD) and mild cognitive impairment (MCI), a clinical syndrome that frequently precedes symptomatic AD. In this study, we modeled AD and MCI bioenergetic dysfunction by transferring mitochondria from MCI, AD and control subject platelets to mtDNA-depleted SH-SY5Y cells. Bioenergetic fluxes and bioenergetics-related infrastructures were characterized in the resulting cytoplasmic hybrid (cybrid) cell lines. Relative to control cybrids, AD an...

  16. Comparison of embedded and added motor imagery training in patients after stroke: study protocol of a randomised controlled pilot trial using a mixed methods approach

    Directory of Open Access Journals (Sweden)

    Andrews Brian

    2009-10-01

    Full Text Available Abstract Background Two different approaches have been adopted when applying motor imagery (MI to stroke patients. MI can be conducted either added to conventional physiotherapy or integrated within therapy sessions. The proposed study aims to compare the efficacy of embedded MI to an added MI intervention. Evidence from pilot studies reported in the literature suggests that both approaches can improve performance of a complex motor skill involving whole body movements, however, it remains to be demonstrated, which is the more effective one. Methods/Design A single blinded, randomised controlled trial (RCT with a pre-post intervention design will be carried out. The study design includes two experimental groups and a control group (CG. Both experimental groups (EG1, EG2 will receive physical practice of a clinical relevant motor task ('Going down, laying on the floor, and getting up again' over a two week intervention period: EG1 with embedded MI training, EG2 with MI training added after physiotherapy. The CG will receive standard physiotherapy intervention and an additional control intervention not related to MI. The primary study outcome is the time difference to perform the task from pre to post-intervention. Secondary outcomes include level of help needed, stages of motor task completion, degree of motor impairment, balance ability, fear of falling measure, motivation score, and motor imagery ability score. Four data collection points are proposed: twice during baseline phase, once following the intervention period, and once after a two week follow up. A nested qualitative part should add an important insight into patients' experience and attitudes towards MI. Semi-structured interviews of six to ten patients, who participate in the RCT, will be conducted to investigate patients' previous experience with MI and their expectations towards the MI intervention in the study. Patients will be interviewed prior and after the intervention period

  17. Numerical studies of an eccentric tube-in-tube helically coiled heat exchanger for IHEP-ADS helium purification system

    CERN Document Server

    Zhang, Jianqin

    2014-01-01

    The tube-in-tube helically coiled (TTHC) heat exchanger is preferred in the purifier of IHEP-ADS helium purification system. The position of an internal tube is usually eccentric in a TTHC heat exchanger in practice, while most TTHC heat exchangers in the literature studied are concentric. In this paper, TTHC heat exchangers with different eccentricity ratios are numerically studied for turbulent flow and heat transfer characteristics under different flow rates. The fluid considered is helium at the pressure of 20Mpa, with temperature dependent thermo-physical properties for the inner tube and the annulus. The inner Nusselt number between the concentric and eccentric TTHC heat exchangers are compared, so is the annulus Nusselt number. The results show that with the eccentricity increasing, the annulus Nusselt number increases substantially. According to the numerical data, new empirical correlations of Nusselt number as a function of Reynolds number and eccentricity for the inner tube and the annulus are pres...

  18. Penrose inequality for asymptotically AdS spaces

    Energy Technology Data Exchange (ETDEWEB)

    Itkin, Igor [Raymond and Beverly Sackler School of Physics and Astronomy, Tel-Aviv University, Tel-Aviv 69978 (Israel); Oz, Yaron, E-mail: yaronoz@post.tau.ac.il [Raymond and Beverly Sackler School of Physics and Astronomy, Tel-Aviv University, Tel-Aviv 69978 (Israel)

    2012-02-28

    In general relativity, the Penrose inequality relates the mass and the entropy associated with a gravitational background. If the inequality is violated by an initial Cauchy data, it suggests a creation of a naked singularity, thus providing means to consider the cosmic censorship hypothesis. We propose a general form of Penrose inequality for asymptotically locally AdS spaces.

  19. Added Responsibilities

    Institute of Scientific and Technical Information of China (English)

    2010-01-01

    Historic monuments in Dengfeng,formally referred to as the Center of Heaven and Earth,in Henan Province,as well as Danxia Landform in several southern and eastern Chinese provinces,were proclaimed UNESCO world heritage sites recently. The group of constructions in Dengfeng includes some of the best examples of ancient Chinese buildings devoted to rituals,science,technology and education. Most of the constructions present vividly a history of central China’s architecture from the last 2,000 years and contain very valuable material for studies.

  20. The epidemiology of mild cognitive impairment (MCI and Alzheimer’s disease (AD in community-living seniors: protocol of the MemoVie cohort study, Luxembourg

    Directory of Open Access Journals (Sweden)

    Perquin Magali

    2012-07-01

    Full Text Available Abstract Background Cognitive impairment and Alzheimer’s disease (AD are increasingly considered a major public health problem. The MemoVie cohort study aims to investigate the living conditions or risk factors under which the normal cognitive capacities of the senior population in Luxembourg (≥ 65 year-old evolve (1 to mild cognitive impairment (MCI – transitory non-clinical stage – and (2 to AD. Identifying MCI and AD predictors undeniably constitutes a challenge in public health in that it would allow interventions which could protect or delay the occurrence of cognitive disorders in elderly people. In addition, the MemoVie study sets out to generate hitherto unavailable data, and a comprehensive view of the elderly population in the country. Methods/design The study has been designed with a view to highlighting the prevalence in Luxembourg of MCI and AD in the first step of the survey, conducted among participants selected from a random sample of the general population. A prospective cohort is consequently set up in the second step, and appropriate follow-up of the non-demented participants allows improving the knowledge of the preclinical stage of MCI. Case-control designs are used for cross-sectional or retrospective comparisons between outcomes and biological or clinical factors. To ensure maximal reliability of the information collected, we decided to opt for structured face to face interviews. Besides health status, medical and family history, demographic and socio-cultural information are explored, as well as education, habitat network, social behavior, leisure and physical activities. As multilingualism is expected to challenge the cognitive alterations associated with pathological ageing, it is additionally investigated. Data relative to motor function, including balance, walk, limits of stability, history of falls and accidents are further detailed. Finally, biological examinations, including ApoE genetic polymorphism are

  1. Global geometric properties of AdS space and the AdS/CFT correspondence

    Institute of Scientific and Technical Information of China (English)

    2001-01-01

    The Poisson kernels and relations between them for a massive scalar field in a unit ball Bn with Hua's metric and conformal flat metric are obtained by describing the Bn as a submanifold of an (n+1)-dimensional embedding space. Global geometric properties of the AdS space are discussed. We show that the(n+1)-dimensional AdS space AdSn+1 is isomorphic to RP1×Bn and boundary of the AdS is isomorphic to RP1×Sn-1. Bulk-boundary propagator and the AdS/CFT like correspondence are demonstrated based on these global geometric properties of the RP1×Bn.

  2. String Theory on AdS Spaces

    NARCIS (Netherlands)

    de Boer, J.

    2000-01-01

    In these notes we discuss various aspects of string theory in AdS spaces. We briefly review the formulation in terms of Green-Schwarz, NSR, and Berkovits variables, as well as the construction of exact conformal field theories with AdS backgrounds. Based on lectures given at the Kyoto YITP Workshop

  3. Constructing the AdS dual of a Fermi liquid: AdS Black holes with Dirac hair

    CERN Document Server

    \\vCubrović, Mihailo; Schalm, Koenraad

    2010-01-01

    We provide new evidence that the holographic dual to a strongly coupled charged Fermi Liquid has a non-zero fermion density in the bulk. We show that the pole-strength of the stable quasiparticle characterizing the Fermi surface is encoded in the spatially averaged AdS probability density of a single normalizable fermion wavefunction in AdS. Recalling Migdal's theorem which relates the pole strength to the Fermi-Dirac characteristic discontinuity in the number density at $\\ome_F$, we conclude that the AdS dual of a Fermi liquid is described by occupied on-shell fermionic modes in AdS. Encoding the occupied levels in the total probability density of the fermion field directly, we show that an AdS Reissner-Nordstr\\"{o}m black hole in a theory with charged fermions has a critical temperature, at which the system undergoes a first-order transition to a black hole with a non-vanishing profile for the bulk fermion field. Thermodynamics and spectral analysis confirm that the solution with non-zero AdS fermion-profil...

  4. Online Ad Assignment with an Ad Exchange

    OpenAIRE

    Dvořák, Wolfgang; Henzinger, Monika

    2016-01-01

    Ad exchanges are becoming an increasingly popular way to sell advertisement slots on the internet. An ad exchange is basically a spot market for ad impressions. A publisher who has already signed contracts reserving advertisement impressions on his pages can choose between assigning a new ad impression for a new page view to a contracted advertiser or to sell it at an ad exchange. This leads to an online revenue maximization problem for the publisher. Given a new impression to sell decide whe...

  5. Is anti-doping analysis so far from clinical, legal or forensic targets?: The added value of close relationships between related disciplines.

    Science.gov (United States)

    Segura, Jordi

    2009-11-01

    There are many areas of common interest between anti-doping laboratories and those working in the clinical, legal and forensic fields. In addition to methodological similarities, there are aspects of the findings in sport drug testing that overlap with other fields in such a way that sport drug testing and clinical, legal or forensic work may benefit from mutual interaction. Three recent examples are presented from the author's experience. Case report 1 concerns the clinical relevance of hCG findings in sport drug testing as potential indicators of the presence of a (testicular) tumour in athletes. Case report 2 refers to difficulties that accredited laboratories can encounter due to differences between national legal systems and the administrative regulation systems of sport authorities. The example involves a network of blood collection for further autologous transfusion. Case report 3 relates to additional forensic-type investigations needed to interpret a situation where intoxication of a whole delegation was responsible for apparent doping cases. Clinical, legal and forensic fields must recognize the added value that some results and developments coming from anti-doping laboratories may have. At the same time anti-doping analysts should be aware of new issues, methodologies and problems appearing in related fields.

  6. Jet physics from static charges in AdS space

    Science.gov (United States)

    Chien, Yang-Ting; Schwartz, Matthew D.; Simmons-Duffin, David; Stewart, Iain W.

    2012-02-01

    Soft interactions with high-energy jets are explored in radial coordinates which exploit the approximately conformal behavior of perturbative gauge theories. In these coordinates, the jets, approximated by Wilson lines, become static charges in Euclidean AdS. The anomalous dimension of the corresponding Wilson line operator is then determined by the potential energy of the charges. To study these Wilson lines we introduce a “conformal gauge” which does not have kinetic mixing between radial and angular directions, and show that a number of properties of Wilson lines are reproduced through relatively simple calculations. For example, certain nonplanar graphs involving multiple Wilson lines automatically vanish. We also discuss the linear growth of the charges’ imaginary potential energy with separation, and a relationship between Wilson line diagrams and Witten diagrams.

  7. Jet Physics from Static Charges in AdS

    CERN Document Server

    Chien, Yang-Ting; Simmons-Duffin, David; Stewart, Iain W

    2011-01-01

    Soft interactions with high-energy jets are explored in radial coordinates which exploit the approximately conformal behavior of perturbative gauge theories. In these coordinates, the jets, approximated by Wilson lines, become static charges in Euclidean AdS. The anomalous dimension of the corresponding Wilson line operator is then determined by the potential energy of the charges. To study these Wilson lines we introduce a "conformal gauge" which does not have kinetic mixing between radial and angular directions, and show that a number of properties of Wilson lines are reproduced through relatively simple calculations. For example, certain non-planar graphs involving multiple Wilson lines automatically vanish. We also discuss the linear growth of the charges' imaginary potential energy with separation, and a relationship between Wilson line diagrams and Witten diagrams.

  8. Added value of a household-level study during an outbreak investigation of Salmonella serotype Saintpaul infections, New Mexico 2008.

    Science.gov (United States)

    Boore, A L; Jungk, J; Russo, E T; Redd, J T; Angulo, F J; Williams, I T; Cheek, J E; Gould, L H

    2013-10-01

    In 2008, nationwide investigations of a Salmonella serotype Saintpaul outbreak led first to consumer warnings for Roma and red round tomatoes, then later for jalapeño and serrano peppers. In New Mexico, where there were a large number of cases but no restaurant-based clusters, the NM Department of Health and the Indian Health Service participated with CDC in individual-level and household-level case-control studies of infections in New Mexico and the Navajo Nation. No food item was associated in the individual-level study. In the household-level study, households with an ill member were more likely to have had jalapeño peppers present during the exposure period and to have reported ever having serrano peppers in the household. This report illustrates the complexity of this investigation, the limitations of traditional individual-level case-control studies when vehicles of infection are ingredients or commonly eaten with other foods, and the added value of a household-level study.

  9. Value Adding Management: A New Facilities Management Concept

    DEFF Research Database (Denmark)

    Jensen, Per Anker; Katchamart, Akarapong

    2011-01-01

    Purpose: To investigate how Facilities Management (FM) can add value and develop a management concept that can assist facilities managers in implementing value adding strategies and practices. Theory: The study is based on the management model for FM included in the European FM standards, recent...... theories on added value of FM and real estate and the related concept of Value Management from building projects. The study is related to the EuroFM research group on The Added Value of FM. Design/methodology/approach: The study outlines a preliminary theoretical based management concept, which...... the relevance of the basic concept and provides an important example of how Value Adding Management can be implemented and added value measured. Originality/value: The study develops a concept of Value Adding Management, which is new in FM literature. It is expected to increase the awareness of the impacts...

  10. Action growth for AdS black holes

    Science.gov (United States)

    Cai, Rong-Gen; Ruan, Shan-Ming; Wang, Shao-Jiang; Yang, Run-Qiu; Peng, Rong-Hui

    2016-09-01

    Recently a Complexity-Action (CA) duality conjecture has been proposed, which relates the quantum complexity of a holographic boundary state to the action of a Wheeler-DeWitt (WDW) patch in the anti-de Sitter (AdS) bulk. In this paper we further investigate the duality conjecture for stationary AdS black holes and derive some exact results for the growth rate of action within the Wheeler-DeWitt (WDW) patch at late time approximation, which is supposed to be dual to the growth rate of quantum complexity of holographic state. Based on the results from the general D-dimensional Reissner-Nordström (RN)-AdS black hole, rotating/charged Bañados-Teitelboim-Zanelli (BTZ) black hole, Kerr-AdS black hole and charged Gauss-Bonnet-AdS black hole, we present a universal formula for the action growth expressed in terms of some thermodynamical quantities associated with the outer and inner horizons of the AdS black holes. And we leave the conjecture unchanged that the stationary AdS black hole in Einstein gravity is the fastest computer in nature.

  11. Monopoles in AdS

    CERN Document Server

    Sutcliffe, Paul

    2011-01-01

    Applications to holographic theories have led to some recent interest in magnetic monopoles in four-dimensional Anti-de Sitter spacetime. This paper is concerned with a study of these monopoles, using both analytic and numerical methods. An approximation is introduced in which the fields of a charge N monopole are explicitly given in terms of a degree N rational map. Within this approximation, it is shown that the minimal energy monopole of charge N has the same symmetry as the minimal energy Skyrmion with baryon number N in Minkowski spacetime. Beyond charge two the minimal energy monopole has only a discrete symmetry, which is often Platonic. The rational map approximation provides an upper bound on the monopole energy and may be viewed as a smooth non-abelian refinement of the magnetic bag approximation, to which it reverts under some additional approximations. The analytic results are supported by numerical solutions obtained from simulations of the non-abelian field theory. A similar analysis is performe...

  12. AdS/CFT Duality User Guide

    CERN Document Server

    Natsuume, Makoto

    2014-01-01

    This is the draft version of a textbook on "real-world" applications of the AdS/CFT duality for beginning graduate students in particle physics and for researchers in the other fields. The aim of this book is to provide background materials such as string theory, general relativity, nuclear physics, nonequilibrium physics, and condensed-matter physics as well as some key applications of the AdS/CFT duality in a single textbook. Contents: (1) Introduction, (2) General relativity and black holes, (3) Black holes and thermodynamics, (4) Strong interaction and gauge theories, (5) The road to AdS/CFT, (6) The AdS spacetime, (7) AdS/CFT - equilibrium, (8) AdS/CFT - adding probes, (9) Basics of nonequilibrium physics, (10) AdS/CFT - nonequilibrium, (11) Other AdS spacetimes, (12) Applications to quark-gluon plasma, (13) Basics of phase transition, (14) AdS/CFT - phase transition.

  13. Child AD/HD Severity and Psychological Functioning in Relation to Divorce, Remarriage, Multiple Transitions and the Quality of Family Relationships

    Science.gov (United States)

    Heckel, Leila; Clarke, Adam R.; Barry, Robert J.; McCarthy, Rory; Selikowitz, Mark

    2013-01-01

    Both Attention-Deficit/Hyperactivity Disorder (AD/HD) and divorce are very prevalent in western societies, and they may occur together. AD/HD is generally viewed as a neurobiological disorder, which has led to a commonly held belief that social-environmental factors play little role in the symptom profile of children diagnosed with the disorder.…

  14. AdS_5 Black Holes with Fermionic Hair

    CERN Document Server

    Burrington, B A; Sabra, W A; Burrington, Benjamin A.; Liu, James T.

    2004-01-01

    The study of new BPS objects in AdS_5 has led to a deeper understanding of AdS/CFT. To help complete this picture, and to fully explore the consequences of the supersymmetry algebra, it is also important to obtain new solutions with bulk fermions turned on. In this paper we construct superpartners of the 1/2 BPS black hole in AdS_5 using a natural set of fermion zero modes. We demonstrate that these superpartners, carrying fermionic hair, have conserved charges differing from the original bosonic counterpart. To do so, we find the R-charge and dipole moment of the new system, as well as the mass and angular momentum, defined through the boundary stress tensor. The complete set of superpartners fits nicely into a chiral representation of AdS_5 supersymmetry, and the spinning solutions have the expected gyromagnetic ratio, g=1.

  15. Ad-hoc and context-dependent adjustments of selective attention in conflict control: an ERP study with visual probes.

    Science.gov (United States)

    Nigbur, R; Schneider, J; Sommer, W; Dimigen, O; Stürmer, B

    2015-02-15

    Cognitive conflict control in flanker tasks has often been described using the zoom-lens metaphor of selective attention. However, whether and how selective attention - in terms of suppression and enhancement - operates in this context has remained unclear. To examine the dynamic interplay of selective attention and cognitive control we used electrophysiological measures and presented task-irrelevant visual probe stimuli at foveal, parafoveal, and peripheral display positions. Target-flanker congruency varied either randomly from trial to trial (mixed-block) or block-wise (fixed-block) in order to induce reactive versus proactive control modes, respectively. Three EEG measures were used to capture ad-hoc adjustments within trials as well as effects of context-based predictions: the N1 component of the visual evoked potential (VEP) to probes, the VEP to targets, and the conflict-related midfrontal N2 component. Results from probe-VEPs indicate that enhanced processing of the foveal target rather than suppression of the peripheral flankers supports interference control. In incongruent mixed-block trials VEPs were larger to probes near the targets. In the fixed-blocks probe-VEPs were not modulated, but contrary to the mixed-block the preceding target-related VEP was affected by congruency. Results of the control-related N2 reveal largest amplitudes in the unpredictable context, which did not differentiate for stimulus and response incongruency. In contrast, in the predictable context, N2 amplitudes were reduced overall and differentiated between stimulus and response incongruency. Taken together these results imply that predictability alters interference control by a reconfiguration of stimulus processing. During unpredictable sequences participants adjust their attentional focus dynamically on a trial-by-trial basis as reflected in congruency-dependent probe-VEP-modulation. This reactive control mode also elicits larger N2 amplitudes. In contrast, when task demands

  16. Brownian motion in AdS/CFT

    NARCIS (Netherlands)

    de Boer, J.; Hubeny, V.E.; Rangamani, M.; Shigemori, M.

    2009-01-01

    We study Brownian motion and the associated Langevin equation in AdS/CFT. The Brownian particle is realized in the bulk spacetime as a probe fundamental string in an asymptotically AdS black hole background, stretching between the AdS boundary and the horizon. The modes on the string are excited by

  17. Level of PICALM, a key component of clathrin-mediated endocytosis, is correlated with levels of phosphotau and autophagy-related proteins and is associated with tau inclusions in AD, PSP and Pick disease.

    Science.gov (United States)

    Ando, Kunie; Tomimura, Karen; Sazdovitch, Véronique; Suain, Valérie; Yilmaz, Zehra; Authelet, Michèle; Ndjim, Marième; Vergara, Cristina; Belkouch, Mounir; Potier, Marie-Claude; Duyckaerts, Charles; Brion, Jean-Pierre

    2016-10-01

    Single nucleotide polymorphisms in PICALM, a key component of clathrin-mediated endocytosis machinery, have been identified as genetic susceptibility loci for late onset Alzheimer's disease (LOAD). We previously reported that PICALM protein levels were decreased in AD brains and that PICALM was co-localised with neurofibrillary tangles in LOAD, familial AD with PSEN1 mutations and Down syndrome. In the present study, we analysed PICALM expression, cell localisation and association with pathological cellular inclusions in other tauopathies and in non-tau related neurodegenerative diseases. We observed that PICALM was associated with neuronal tau pathology in Pick disease and in progressive supranuclear palsy (PSP) and co-localised with both 3R and 4R tau positive inclusions unlike in corticobasal degeneration (CBD) or in frontotemporal lobar degeneration (FTLD)-MAPT P301L. PICALM immunoreactivities were not detected in tau-positive tufted astrocytes in PSP, astrocytic plaques in CBD, Lewy bodies in Lewy body disease, diffuse type (LBD) and in TDP-43-positive inclusions in FTLD. In the frontal cortex in tauopathies, the ratio of insoluble to soluble PICALM was increased while the level of soluble PICALM was decreased and was inversely correlated with the level of phosphotau. PICALM decrease was also significantly correlated with increased LC3-II and decreased Beclin-1 levels in tauopathies and in non-tau related neurodegenerative diseases. These results suggest that there is a close relationship between abnormal PICALM processing, tau pathology and impairment of autophagy in human neurodegenerative diseases.

  18. Optimization studies of photo-neutron production in high- metallic targets using high energy electron beam for ADS and transmutation

    Indian Academy of Sciences (India)

    V C Petwal; V K Senecha; K V Subbaiah; H C Soni; S Kotaiah

    2007-02-01

    Monte Carlo calculations have been performed using MCNP code to study the optimization of photo-neutron yield for different electron beam energies impinging on Pb, W and Ta cylindrical targets of varying thickness. It is noticed that photo-neutron yield can be increased for electron beam energies ≥ 100 MeV for appropriate thickness of the target. It is also noticed that it can be maximized by further increasing the thickness of the target. Further, at higher electron beam energy heat gradient in the target decreases, which facilitates easier heat removal from the target. This can help in developing a photo-neutron source based on electron LINAC by choosing appropriate electron beam energy and target thickness to optimize the neutron flux for ADS, transmutation studies and as high energy neutron source etc. Photo-neutron yield for different targets, optimum target thickness and photo-neutron energy spectrum and heat deposition by electron beam for different incident energy is presented.

  19. Entanglement entropy for free scalar fields in AdS

    CERN Document Server

    Sugishita, Sotaro

    2016-01-01

    We compute entanglement entropy for free massive scalar fields in anti-de Sitter (AdS) space. The entangling surface is a minimal surface whose boundary is a sphere at the boundary of AdS. The entropy can be evaluated from the thermal free energy of the fields on a topological black hole by using the replica method. In odd-dimensional AdS, exact expressions of the Renyi entropy S_n are obtained for arbitrary n. We also evaluate 1-loop corrections coming from the scalar fields to holographic entanglement entropy. Applying the results, we compute the leading difference of entanglement entropy between two holographic CFTs related by a renormalization group flow triggered by a double trace deformation. The difference is proportional to the shift of a central charge under the flow.

  20. A study of the risk for Alzheimer’s disease in first-degree relatives of patients with affective disorders

    Institute of Scientific and Technical Information of China (English)

    徐文炜

    2013-01-01

    Objective To investigate the prevalence of Alzheimer’s disease (AD) in first-degree relatives of patients with affective disorders,and to evaluate the risk of AD in firstdegree relatives of the patients with affective disorders.Methods Patients with affective disorders meeting"DSM-Ⅳ-TR"criteria (affective disorders group) and their healthy spouses (conrol group) were recruited in this study (n=109 each) .The first-degree relatives in-

  1. Preclinical pharmacology and toxicology study of Ad-hTERT-E1a-Apoptin, a novel dual cancer-specific oncolytic adenovirus

    Energy Technology Data Exchange (ETDEWEB)

    Qi, Yanxin [State Key Laboratory of Polymer Physics and Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022 (China); Institute of Military Veterinary, Academy of Military Medical Sciences of PLA, Changchun 130122 (China); Guo, Huanhuan [Institute of Military Veterinary, Academy of Military Medical Sciences of PLA, Changchun 130122 (China); Changchun Brother Biotech Co., Ltd., Changchun, 130000 (China); Hu, Ningning; He, Dongyun [Institute of Military Veterinary, Academy of Military Medical Sciences of PLA, Changchun 130122 (China); The Key Laboratory of Jilin Province for Zoonosis Prevention and Control, Changchun 130122 (China); Zhang, Shi [Institute of Military Veterinary, Academy of Military Medical Sciences of PLA, Changchun 130122 (China); School of Clinical Medicine, Jilin University, Changchun 130001 (China); Chu, Yunjie [Affiliated Hospital of Changchun University of Traditional Chinese Medicine, Changchun 130021 (China); Huang, Yubin [State Key Laboratory of Polymer Physics and Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022 (China); Li, Xiao, E-mail: lixiao06@mails.jlu.edu.cn [Institute of Military Veterinary, Academy of Military Medical Sciences of PLA, Changchun 130122 (China); The Key Laboratory of Jilin Province for Zoonosis Prevention and Control, Changchun 130122 (China); Sun, LiLi, E-mail: linjiaxiaoya@163.com [Department of Head and Neck Surgery, Tumor Hospital of Jilin Province, Changchun 130012 (China); Jin, Ningyi, E-mail: ningyij@126.com [Institute of Military Veterinary, Academy of Military Medical Sciences of PLA, Changchun 130122 (China); The Key Laboratory of Jilin Province for Zoonosis Prevention and Control, Changchun 130122 (China)

    2014-10-15

    Clinical studies have demonstrated that conditionally replicating adenovirus is safe. We constructed an oncolytic adenovirus, Ad-hTERT-E1a-Apoptin, using a cancer-specific promoter (human telomerase reverse transcriptase promoter, hTERTp) and a cancer cell-selective apoptosis-inducing gene (Apoptin). Ad-hTERT-E1a-Apoptin was proven effective both in vitro and in vivo in our previous study. In this study, the preclinical safety profiles of Ad-hTERT-E1a-Apoptin in animal models were investigated. At doses of 5.0 × 10{sup 8}, 2.5 × 10{sup 9}, and 1.25 × 10{sup 10} viral particles (VP)/kg, Ad-hTERT-E1a-Apoptin had no adverse effects on mouse behavior, muscle cooperation, sedative effect, digestive system, and nervous systems, or on beagle cardiovascular and respiratory systems at 5.0 × 10{sup 8}, 2.5 × 10{sup 9}, and 1.25 × 10{sup 10} VP/kg doses. In acute toxicity tests in mice, the maximum tolerated dose > 5 × 10{sup 10} VP/kg. There was no inflammation or ulceration at the injection sites within two weeks. In repeat-dose toxicological studies, the no observable adverse effect levels of Ad-hTERT-E1a-Apoptin in rats (1.25 × 10{sup 10} VP/kg) and beagles (2.5 × 10{sup 9} VP/kg) were 62.5- and 12.5-fold of the proposed clinical dose, respectively. The anti-virus antibody was produced in animal sera. Bone marrow examination revealed no histopathological changes. Guinea pigs sensitized by three repeated intraperitoneal injections of 1.35 × 10{sup 10} VP/mL Ad-hTERT-E1a-Apoptin each and challenged by one intravenous injection of 1.67 × 10{sup 8} VP/kg Ad-hTERT-E1a-Apoptin did not exhibit any sign of systemic anaphylaxis. Our data from different animal models suggest that Ad-hTERT-E1a-Apoptin is a safe anti-tumor therapeutic agent. - Highlights: • We use the rodents and non-rodents animal models to evaluation Ad-hTERT-E1a-Apoptin. • Ad-hTERT-E1a-Apoptin is a safe anti-tumor therapeutic agent. • Demonstrate the safety and feasibility dose of injected Ad

  2. Sources of ground movement at Vesuvius before the AD 79 eruption: Evidence from contemporary accounts and archaeological studies

    Science.gov (United States)

    Marturano, Aldo

    2008-11-01

    Historical sources have recorded earthquake shocks, their effects and difficulties that local inhabitants experienced before the AD 79 Pompeii eruption. Archaeological studies pointed out the effects of such seismicity, and have also evidenced that several water crises were occurring at Pompeii in that period. Indeed numerous sources show that, at the time of eruption, and probably some time before, the civic aqueduct, having ceased to be supplied by the regional one, was out of order and that a new one was being built. Since Roman aqueducts were usually built with a recommended minimum mean slope of 20 cm/km and Pompeii's aqueduct sloped from the nearby Apennines toward the town, this slope could have been easily cancelled by uplift that occurred in the area even if this was only moderate. For the crustal deformations a volcanic origin is proposed and a point source model is used to explain the observations. Simple analysis of the available data suggests that the ground deformations were caused by a < 2 km 3 volumetric change at a depth of ˜ 8 km that happened over the course of several decades.

  3. Generalized thermodynamic identity and new Maxwell's law for charged AdS black hole

    CERN Document Server

    Zhao, Zixu

    2016-01-01

    We study the thermodynamic properties of the RN-AdS black hole in full phase space and propose a generalized thermodynamic identity. As an example, we use it to find relations of thermodynamical coefficients between the grand canonical and canonical ensembles. We also show, for the first order phase transition, that the usual Maxwell's equal area law should be extended to a new form for the RN-AdS black hole.

  4. A combined study for turning CO$_2$ and H$_2$O into value-added products in a dielectric barrier discharge

    CERN Document Server

    Snoeckx, Ramses; Aerts, Robby; Dufour, Thierry; Reniers, François; Bogaerts, Annemie

    2016-01-01

    A combination of experiments and extensive modelling, including a chemical kinetics analysis, was performed for a CO$_2$/H$_2$O plasma in a dielectric barrier discharge. This provides a better understanding of the mechanisms related to the reactivity of the plasma and of the conversions into value-added products, such as methanol.

  5. Effect of dexamethasone added to lidocaine in supraclavicular brachial plexus block: A prospective, randomised, double-blind study

    Directory of Open Access Journals (Sweden)

    Prashant A Biradar

    2013-01-01

    Full Text Available Background: Different additives have been used to prolong brachial plexus block. We performed a prospective, randomised, double-blind study to evaluate the effect of dexamethasone added to lidocaine on the onset and duration of supraclavicular brachial plexus block as this is the most common type of brachial block performed in our institute. Methods: Sixty American Society of Anaesthesiologist′s physical status I and II patients undergoing elective hand, forearm and elbow surgery under brachial plexus block were randomly allocated to receive either 1.5% lidocaine (7 mg/kg with adrenaline (1:200,000 and 2 ml of normal saline (group C, n=30 or 1.5% lidocaine (7 mg/kg with adrenaline (1:200,000 and 2 ml of dexamethasone (8 mg (group D, n=30. The block was performed using a nerve stimulator. Onset and duration of sensory and motor blockade were assessed. The sensory and motor blockade of radial, median, ulnar and musculocutaneous nerves were evaluated and recorded at 5, 10, 20, 120 min, and at every 30 min thereafter. Results: Two patients were excluded from the study because of block failure. The onset of sensory and motor blockade (13.4±2.8 vs. 16.0±2.3 min and 16.0±2.7 vs. 18.7±2.8 min, respectively were significantly more rapid in the dexamethasone group than in the control group ( P=0.001. The duration of sensory and motor blockade (326±58.6 vs. 159±20.1 and 290.6±52.7 vs. 135.5±20.3 min, respectively were significantly longer in the dexamethasone group than in the control group ( P=0.001. Conclusion: Addition of dexamethasone to 1.5% lidocaine with adrenaline in supraclavicular brachial plexus block speeds the onset and prolongs the duration of sensory and motor blockade.

  6. Analytical study of the frequency shifts of micro and nano clamped–clamped beam resonators due to an added mass

    KAUST Repository

    Bouchaala, Adam M.

    2016-03-18

    We present analytical formulations to calculate the induced resonance frequency shifts of electrically actuated clamped–clamped micro and nano (Carbon nanotube) beams due to an added mass. Based on the Euler–Bernoulli beam theory, we investigate the linear dynamic responses of the beams added masses, which are modeled as discrete point masses. Analytical expressions based on perturbation techniques and a one-mode Galerkin approximation are developed to calculate accurately the frequency shifts under a DC voltage as a function of the added mass and position. The analytical results are compared to numerical solution of the eigenvalue problem. Results are shown for the fundamental as well as the higher-order modes of the beams. The results indicate a significant increase in the frequency shift, and hence the sensitivity of detection, when scaling down to nano scale and using higher-order modes. © 2016 Springer Science+Business Media Dordrecht

  7. An Empirical Comparative Study of Checklist based and Ad Hoc Code Reading Techniques in a Distributed Groupware Environment

    CERN Document Server

    Akinola, Olalekan S

    2009-01-01

    Software inspection is a necessary and important tool for software quality assurance. Since it was introduced by Fagan at IBM in 1976, arguments exist as to which method should be adopted to carry out the exercise, whether it should be paper based or tool based, and what reading technique should be used on the inspection document. Extensive works have been done to determine the effectiveness of reviewers in paper based environment when using ad hoc and checklist reading techniques. In this work, we take the software inspection research further by examining whether there is going to be any significant difference in defect detection effectiveness of reviewers when they use either ad hoc or checklist reading techniques in a distributed groupware environment. Twenty final year undergraduate students of computer science, divided into ad hoc and checklist reviewers groups of ten members each were employed to inspect a medium sized java code synchronously on groupware deployed on the Internet. The data obtained were...

  8. Asymptotically AdS spacetimes with a timelike Kasner singularity

    Science.gov (United States)

    Ren, Jie

    2016-07-01

    Exact solutions to Einstein's equations for holographic models are presented and studied. The IR geometry has a timelike cousin of the Kasner singularity, which is the less generic case of the BKL (Belinski-Khalatnikov-Lifshitz) singularity, and the UV is asymptotically AdS. This solution describes a holographic RG flow between them. The solution's appearance is an interpolation between the planar AdS black hole and the AdS soliton. The causality constraint is always satisfied. The entanglement entropy and Wilson loops are discussed. The boundary condition for the current-current correlation function and the Laplacian in the IR is examined. There is no infalling wave in the IR, but instead, there is a normalizable solution in the IR. In a special case, a hyperscaling-violating geometry is obtained after a dimensional reduction.

  9. The impact of net value added on predicting the earnings and operating cash flow: An empirical study based on Tehran Stock Exchange

    Directory of Open Access Journals (Sweden)

    Omid Imani Khoshkhoo

    2013-12-01

    Full Text Available Information content of earnings and its components and other issues except the earnings such as the operating cash flow (OCF have been tested widely in the accounting and finance literature. Since they have had an essential role in most cases including financial reporting, contracts and evaluation models, specifying the items and financial variables that have had a significant relationship with these two variables are expected to be of utmost importance. One example of these variables and indicators is the value added. Although this variable has an economic concept, reporting of value added to the beneficiaries of business entity as the value-added statement has been observed in the field of accounting theories for many years. The main objective of this study was to investigate the effect of net value added (NVA as the basic result of value-added statement in predicting the accounting earnings and operating cash flow. For this purpose, the relationship of changes in net value added with the changes in accounting earnings and operating cash flow of listed companies in Tehran Stock Exchange from 2007 to 2011 was tested. Firstly the Single variable cross-sectional regression was analyzed and then the panel data analysis with the PLS technique was used to do a pooled analysis. The results of testing research hypothesis imply the significant relationship between changes in net value added and accounting earnings in the listed companies as cross-sectional and pooled forms. The results showed no significant relationship between changes in net value added and operating cash flow in the listed companies neither in cross-sectional nor pooled form.

  10. Constructing Lifshitz solutions from AdS

    CERN Document Server

    Cassani, Davide

    2011-01-01

    Under general assumptions, we show that a gravitational theory in d+1 dimensions admitting an AdS solution can be reduced to a d-dimensional theory containing a Lifshitz solution with dynamical exponent z=2. Working in a d=4, N=2 supergravity setup, we prove that if the AdS background is N=2 supersymmetric, then the Lifshitz geometry preserves 1/4 of the supercharges, and we construct the corresponding Killing spinors. We illustrate these results in examples from supersymmetric consistent truncations of type IIB supergravity, enhancing the class of known 4-dimensional Lifshitz solutions of string theory. As a byproduct, we find a new AdS4 x S1 x T(1,1) solution of type IIB.

  11. Geospatial modeling approach to monument construction using Michigan from A.D. 1000-1600 as a case study.

    Science.gov (United States)

    Howey, Meghan C L; Palace, Michael W; McMichael, Crystal H

    2016-07-01

    Building monuments was one way that past societies reconfigured their landscapes in response to shifting social and ecological factors. Understanding the connections between those factors and monument construction is critical, especially when multiple types of monuments were constructed across the same landscape. Geospatial technologies enable past cultural activities and environmental variables to be examined together at large scales. Many geospatial modeling approaches, however, are not designed for presence-only (occurrence) data, which can be limiting given that many archaeological site records are presence only. We use maximum entropy modeling (MaxEnt), which works with presence-only data, to predict the distribution of monuments across large landscapes, and we analyze MaxEnt output to quantify the contributions of spatioenvironmental variables to predicted distributions. We apply our approach to co-occurring Late Precontact (ca. A.D. 1000-1600) monuments in Michigan: (i) mounds and (ii) earthwork enclosures. Many of these features have been destroyed by modern development, and therefore, we conducted archival research to develop our monument occurrence database. We modeled each monument type separately using the same input variables. Analyzing variable contribution to MaxEnt output, we show that mound and enclosure landscape suitability was driven by contrasting variables. Proximity to inland lakes was key to mound placement, and proximity to rivers was key to sacred enclosures. This juxtaposition suggests that mounds met local needs for resource procurement success, whereas enclosures filled broader regional needs for intergroup exchange and shared ritual. Our study shows how MaxEnt can be used to develop sophisticated models of past cultural processes, including monument building, with imperfect, limited, presence-only data.

  12. Ad libitum fluid intake leads to no leg swelling in male Ironman triathletes – an observational field study

    Directory of Open Access Journals (Sweden)

    Meyer Michael

    2012-09-01

    Full Text Available Abstract Background An association between fluid intake and limb swelling has been described for 100-km ultra-marathoners. We investigated a potential development of peripheral oedemata in Ironman triathletes competing over 3.8 km swimming, 180 km cycling and 42.2 km running. Methods In 15 male Ironman triathletes, fluid intake, changes in body mass, fat mass, skeletal muscle mass, limb volumes and skinfold thickness were measured. Changes in renal function, parameters of skeletal muscle damage, hematologic parameters and osmolality in both serum and urine were determined. Skinfold thicknesses at hands and feet were measured using LIPOMETER® and changes of limb volumes were measured using plethysmography. Results The athletes consumed a total of 8.6 ± 4.4 L of fluids, equal to 0.79 ± 0.43 L/h. Body mass, skeletal muscle mass and the volume of the lower leg decreased (p p >0.05. The decrease in skeletal muscle mass was associated with the decrease in body mass (p p >0.05. Haemoglobin, haematocrit and serum sodium remained unchanged (p >0.05. Osmolality in serum and urine increased (p +] (r = −0.52, p r = −0.60, p Conclusions In these Ironman triathletes, ad libitum fluid intake maintained plasma [Na+] and plasma osmolality and led to no peripheral oedemata. The volume of the lower leg decreased and the decrease was unrelated to fluid intake. Future studies may investigate ultra-triathletes competing in a Triple Iron triathlon over 11.4 km swimming, 540 km cycling and 126.6 km running to find an association between fluid intake and the development of peripheral oedemata.

  13. Ad Hoc网络%Ad Hoc Network

    Institute of Scientific and Technical Information of China (English)

    王海涛

    2005-01-01

    首先介绍了Ad Hoc网络的基本概念、技术特点以及关键技术等,然后较为全面地归纳了Ad Hoc网络的典型应用,最后讨论了Ad Hoc网络的发展趋势和有待解决的问题.

  14. Ad hoc网络技术讲座第3讲Ad hoc网络采用QoS信令机制的研究%Ad hoc Network Serials Part 3:Studies on Ad hoc Networks Using QoS Signaling Protocol

    Institute of Scientific and Technical Information of China (English)

    王海涛; 郑少仁

    2003-01-01

    信令机制通常是网络中最复杂的功能部件之一,本文首先介绍了移动Ad hoc网络(MANET)中采用QoS信令机制的必要性,然后详细说明和分析了RSVP及其改进协议在MANET中应用的可行性.接着讨论了一种适合于MANET的带内信令机制--INSIGNIA信令机制及其改进协议,最后对全文进行了总结.

  15. Integrated Study of AD-Net Mie-Lidar Network and Data Assimilated CTM for Asian Dust Epidemiology in Japan

    Science.gov (United States)

    Shimizu, Atsushi; Nishizawa, Tomoaki; Sugimoto, Nobuo; Matsui, Ichiro; Kobayashi, Hiroshi; Maki, Takashi; Sekiyama, Thomas T.; Kanatani, Kumiko

    2016-06-01

    Mie-scattering lidar data are going to be incorporated into data assimilation in chemical transport model to represent more reliable / useful horizontal distribution of Asian dust over Japan. The result is utilized in an epidemiology which surveys effect of Asian dust to human health. Wider application of AD-Net is expected in the field of environmental researches.

  16. Combining Q2MM Modeling and Kinetic Studies for Refinement of the Osmium-catalyzed Asymmetric Dihydroxylation (AD) Mnemonic

    DEFF Research Database (Denmark)

    Fristrup, Peter; Jensen, Gitte Holm; Andersen, Marie Louise Nygaard

    2006-01-01

    The interactions between the substrate and the ligand in the Sharpless AD reaction have been examined in detail, using a combination of substrate competition experiments and molecular modeling of transition states. There is a good agreement between computational and experimental results, in parti...

  17. Słownictwo z dziedziny mediów, reklamy i public relations jako przykład języka zawodowego.

    OpenAIRE

    Nerwiński, Wojciech

    2007-01-01

    In my thesis “Vocabulary from media, advertising and public relations as an example of professional language”. I have analysed vocabulary which concerns media, advertising and public relations in Poland. These three questions are very young in Poland’s language and home market. First of all I show in my thesis the research and development of the professional language in Poland. Afterwards I study the word's lexical in my work, as a criterion taken to the Polish language. English words that ha...

  18. Retinal vascular lesions in patients with type 2 diabetes mellitus of Caucasian and Asian origin - baseline results from the AdRem study

    NARCIS (Netherlands)

    Stolk, R.P.; van Schooneveld, M.J.; Cruickshank, J.K.; Hughes, A.D.; Stanton, A.; Lu, J.; Patel, A.; Thom, S.A.; Grobbee, D.E.; Vingerling, J.R.

    2008-01-01

    Objective: To describe prevalent vascular retinal lesions among patients with type 2 diabetes enrolled in the ADVANCE Retinal measurement study (AdRem), a sub-study of the Action in Diabetes and Vascular disease - Preterax and Diamicron Controlled Evaluation (ADVANCE) trial. Research Design and Meth

  19. Retinal vascular lesions in patients of Caucasian and Asian origin with type 2 diabetes - Baseline results from the ADVANCE Retinal Measurements (AdRem) study

    NARCIS (Netherlands)

    Stolk, Ronald P.; van Schooneveld, Mary J.; Cruickshank, J. Kennedy; Hughes, Alun D.; Stanton, Alice; Lu, Juming; Patel, Anushka; Thom, Simon A. McG.; Grobbee, Diederick E.; Vingerling, Johannes R.

    2008-01-01

    OBJECTIVE - The objective of this study was to describe prevalent vascular retinal lesions among patients with type 2 diabetes enrolled in the ADVANCE Retinal Measurements (AdRem) study, a substudy of the Action in Diabetes and Vascular Disease: Preterax and Diamicron MR Controlled Evaluation (ADVAN

  20. A proof-of-principle study of epigenetic therapy added to neoadjuvant doxorubicin cyclophosphamide for locally advanced breast cancer.

    Directory of Open Access Journals (Sweden)

    Claudia Arce

    Full Text Available Aberrant DNA methylation and histone deacetylation participate in cancer development and progression; hence, their reversal by inhibitors of DNA methylation and histone deacetylases (HDACs is at present undergoing clinical testing in cancer therapy. As epigenetic alterations are common to breast cancer, in this proof-of-concept study demethylating hydralazine, plus the HDAC inhibitor magnesium valproate, were added to neoadjuvant doxorubicin and cyclophosphamide in locally advanced breast cancer to assess their safety and biological efficacy.This was a single-arm interventional trial on breast cancer patients (ClinicalTrials.gov Identifier: NCT00395655. After signing informed consent, patients were typed for acetylator phenotype and then treated with hydralazine at 182 mg for rapid-, or 83 mg for slow-acetylators, and magnesium valproate at 30 mg/kg, starting from day -7 until chemotherapy ended, the latter consisting of four cycles of doxorubicin 60 mg/m2 and cyclophosphamide 600 mg/m2 every 21 days. Core-needle biopsies were taken from primary breast tumors at diagnosis and at day 8 of treatment with hydralazine and valproate.16 patients were included and received treatment as planned. All were evaluated for clinical response and toxicity and 15 for pathological response. Treatment was well-tolerated. The most common toxicity was drowsiness grades 1-2. Five (31% patients had clinical CR and eight (50% PR for an ORR of 81%. No patient progressed. One of 15 operated patients (6.6% had pathological CR and 70% had residual disease <3 cm. There was a statistically significant decrease in global 5mC content and HDAC activity. Hydralazine and magnesium valproate up- and down-regulated at least 3-fold, 1,091 and 89 genes, respectively.Hydralazine and magnesium valproate produce DNA demethylation, HDAC inhibition, and gene reactivation in primary tumors. Doxorubicin and cyclophosphamide treatment is safe, well-tolerated, and appears to increase the

  1. Scattering States in AdS/CFT

    Energy Technology Data Exchange (ETDEWEB)

    Fitzpatrick, A.Liam; /Boston U.; Kaplan, Jared; /SLAC

    2012-02-14

    We show that suitably regulated multi-trace primary states in large N CFTs behave like 'in' and 'out' scattering states in the flat-space limit of AdS. Their transition matrix elements approach the exact scattering amplitudes for the bulk theory, providing a natural CFT definition of the flat space S-Matrix. We study corrections resulting from the AdS curvature and particle propagation far from the center of AdS, and show that AdS simply provides an IR regulator that disappears in the flat space limit.

  2. Study of the IDS in wireless Ad Hoc networks based on mobile agents%基于移动代理的无线Ad Hoc网络IDS研究

    Institute of Scientific and Technical Information of China (English)

    张念丽

    2006-01-01

    介绍了无线Ad Hoc网络的特点和面临的安全问题,分析了移动代理在Ad Hoc网络入侵检测系统中的适用性,给出了一种基于移动代理的无线Ad Hoc网络入侵检测系统模型.

  3. Ads in Indonesia

    Directory of Open Access Journals (Sweden)

    Wulan Roro Retno

    2017-01-01

    Full Text Available Cosmetics industry created the beauty myth for women through advertising. A cosmetic ad in Indonesia has spread a new concept of white skin: East Asia beauty myth. The white concept of Asia white skin basically derived from colonial legacy. The purpose of the research was analyzing the beauty myth in Indonesia ads using postcolonial perspective. The principal result brought the discourse analysis and postcolonial perspective a new insight in communication research. Particularly on media and cultural studies. Major conclusions showed that the beauty myth since the Dutch colonial period never been change. The main concept is always in colonialism’s idea: “white is better”. The West is better than the East.

  4. Intrusion detection in wireless ad-hoc networks

    CERN Document Server

    Chaki, Nabendu

    2014-01-01

    Presenting cutting-edge research, Intrusion Detection in Wireless Ad-Hoc Networks explores the security aspects of the basic categories of wireless ad-hoc networks and related application areas. Focusing on intrusion detection systems (IDSs), it explains how to establish security solutions for the range of wireless networks, including mobile ad-hoc networks, hybrid wireless networks, and sensor networks.This edited volume reviews and analyzes state-of-the-art IDSs for various wireless ad-hoc networks. It includes case studies on honesty-based intrusion detection systems, cluster oriented-based

  5. Analisis Kinerja Keuangan Dengan Menggunakan Rasio-Rasio Keuangan Dan Economic Value Added (Studi Kasus: PT. Bank Syariah Mandiri

    Directory of Open Access Journals (Sweden)

    Endri Piliang

    2008-08-01

    Full Text Available This paper analyzes the financial peformance of Bank Syariah Mandiri (BSM using financial ratios and Economic Value Added (EVA method. The ratio of Net Profit Margin (NPM, Return on Asset (ROA, Return on Equity (ROE, and Capital Adequacy Ratio (CAR show fluctuative result. However, on average, during 2003-2006 financial performance of BSM was increased considerably. While using EVA method, its result during 2003-2006 tend to decreased and even negative. The best performance was happening in 2003, whereby during 2004 - 2006 EVA result was lower than zero meaning that financial performance of BSM do not have any economic contribution to the institution especially for the interest of investor.Keywords: Economic Value Added, NPM, ROA, ROE, CAR

  6. 关于EVA贴现模型的探讨%Study on discounted economic value added valuation method

    Institute of Scientific and Technical Information of China (English)

    范洪波; 张丽梅

    2004-01-01

    主要介绍了公司价值评估的一种方法--EVA贴现估价法(The Discounted Economic Value Added Valuation Method).与股利贴现模型和自由现金流模型相比EVA贴现估价法的优越性在于获取数据较容易,重视账面值的分析,目前越来越受到关注.

  7. Age-dependent modifications of AMPA receptor subunit expression levels and related cognitive effects in 3xTg-AD mice

    Directory of Open Access Journals (Sweden)

    Pamela eCantanelli

    2014-08-01

    Full Text Available GluA1, GluA2, GluA3, and GluA4 are the constitutive subunits of AMPA receptors (AMPARs, the major mediators of fast excitatory transmission in the mammalian central nervous system. Most AMPARs are Ca2+-impermeable because of the presence of the GluA2 subunit. GluA2 mRNA undergoes an editing process that results in a Q to R substitution, a key factor in the regulation of AMPAR Ca2+-permeability. AMPARs lacking GluA2 or containing the unedited subunit are permeable to Ca2+ and Zn2+. The phenomenon physiologically modulates synaptic plasticity while, in pathologic conditions, leads to increased vulnerability to excitotoxic neuronal death. Given the importance of these subunits, we have therefore evaluated possible associations between changes in expression levels of AMPAR subunits and development of cognitive deficits in 3xTg-AD mice, a widely investigated transgenic mouse model of Alzheimer’s disease. With qRT-PCR, we assayed hippocampal mRNA expression levels of GluA1-4 subunits occurring in young [3 months of age (m.o.a.] and old (12 m.o.a Tg-AD mice and made comparisons with levels found in age-matched wild type (WT mice. Efficiency of GluA2 RNA editing was also analyzed. All animals were cognitively tested for short- and long-term spatial memory with the Morris Water Maze (MWM navigation task. 3xTg-AD mice showed age-dependent decreases of mRNA levels for all the AMPAR subunits, with the exception of GluA2. Editing remained fully efficient with aging in 3xTg-AD and WT mice. A one-to-one correlation analysis between MWM performances and GluA1-4 mRNA expression profiles showed negative correlations between GluA2 levels and MWM performances in young 3xTg-AD mice. On the contrary, positive correlations between GluA2 mRNA and MWM performances were found in young WT mice. Our data suggest that increases of AMPARs that contain GluA1, GluA3, and GluA4 subunits may help in maintaining cognition in pre-symptomatic 3xTg-AD mice.

  8. Feasibility study of a cosmetic cream added with aqueous extract and oil from date (Phoenix dactylifera L.) fruit seed using experimental design.

    Science.gov (United States)

    Lecheb, Fatma; Benamara, Salem

    2015-01-01

    This article reports on the feasibility study of a cosmetic cream added with aqueous extract and oil from date (Phoenix dactylifera L.) fruit seed using experimental design. First, the mixture design was applied to optimize the cosmetic formula. The responses (dependent variables) were the spreadability (YSp) and viscosity (YVis), the factors (independent variables) being the weight proportions of the fatty phase (X1), the aqueous date seed extract (X2), and the beeswax (X3). Second, the cosmetic stability study was conducted by applying a full factorial design. Here, three responses were considered [spreadability (Sp), viscosity (Vis), and peroxide index (PI)], the independent variables being the concentration of the date seed oil (DSO) (x1), storage temperature (x2), and storage time (x3). Results showed that in the case of mixture design, the second-order polynomial equations correctly described experimental data. Globally, results show that there is a relatively wide composition range to ensure a suitable cosmetic cream from the point of view of Sp and Vis. Regarding the cosmetic stability, the storage time was found to be the most influential factor on both Vis and PI, which are considered here as indicators of physical and chemical stability of the emulsion, respectively. Finally, the elaborated and commercial cosmetics were compared in terms of pH, Sp, and centrifugation test (Ct).

  9. Superradiant instability in AdS

    CERN Document Server

    Ganchev, Bogdan

    2016-01-01

    The phenomenon of superradiance in the context of asymptotically global AdS spacetimes is investigated with particular accent on its effect on the stability of the systems under consideration. To this end, the concept of an asymptotically AdS spacetime is explained, together with its implications on the boundary conditions at $\\mathcal{I}$, as well as the Newman-Penrose-Teukolsky formalism, whereby the Teukolsky master equation in a most general form for Kerr-AdS is given. Furthermore, work done in the cases of RN-AdS and Kerr-AdS is laid out in a concise manner, putting emphasis on the important steps taken in determining the endpoint of the superradiant instability in the two configurations. For the former this turns out to be a black hole with reduced charge and a static charged scalar condensate around it, whereas for the latter two of the more probable outcomes are presented, both of which imply a violation of one of the cosmic censorships.

  10. Recurring Anomaly Detection System (ReADS)

    Data.gov (United States)

    National Aeronautics and Space Administration — Overview: ReADS can analyze text reports, such as aviation reports and problem or maintenance records. ReADS uses text clustering algorithms to group loosely related...

  11. Vehicular ad hoc network security and privacy

    CERN Document Server

    Lin, X

    2015-01-01

    Unlike any other book in this area, this book provides innovative solutions to security issues, making this book a must read for anyone working with or studying security measures. Vehicular Ad Hoc Network Security and Privacy mainly focuses on security and privacy issues related to vehicular communication systems. It begins with a comprehensive introduction to vehicular ad hoc network and its unique security threats and privacy concerns and then illustrates how to address those challenges in highly dynamic and large size wireless network environments from multiple perspectives. This book is richly illustrated with detailed designs and results for approaching security and privacy threats.

  12. 基于TCP的Ad Hoc网络路由协议性能分析与仿真%The Study of Routing Protocol's Performance in Ad Hoc Network Based on TCP

    Institute of Scientific and Technical Information of China (English)

    刘树立; 冯玉宾

    2013-01-01

    文章简述了Ad Hoc网络的组网特点以及Ad Hoc网络中典型的AODV、DSDV和DSR路由协议.对于Ad Hoc网络分别采用不同的路由协议时在传输层使用TCP Reno协议传输数据进行了仿真,仿真结果的分析表明了按需路由在Ad Hoc网络环境下建立TCP连接时具有更好的性能.并进一步指出了Ad Hoc网络的研究方向.

  13. Delta Plots in the study of individual differences: New tools reveal response inhibition deficits in AD/HD That are eliminated by methylphenidate treatment

    NARCIS (Netherlands)

    K.R. Ridderinkhof; A. Scheres; J. Oosterlaan; J.A. Sergeant

    2005-01-01

    The authors highlight the utility of distribution-analytical techniques in the study of individual differences and clinical disorders. Cognitive deficits associated with attention-deficit/hyperactivity disorder (AD/HD) were examined by using delta-plot analyses of performance data (reaction time and

  14. Delta Plots in the Study of Individual Differences : New Tools Reveal Response Inhibition Deficits in AD-HD That Are Eliminated by Methylphenidate Treatment

    NARCIS (Netherlands)

    Ridderinkhof, K.R.; Scheres, A.P.J.; Oosterlaan, J.; Sergeant, J.A.

    2005-01-01

    The authors highlight the utility of distribution-analytical techniques in the study of individual differences and clinical disorders. Cognitive deficits associated with attention-deficit/hyperactivity disorder (AD/HD) were examined by using delta-plot analyses of performance data (reaction time and

  15. The effect of adding group-based counselling to individual lifestyle counselling on changes in dietary intake. The Inter99 study--a randomized controlled trial

    DEFF Research Database (Denmark)

    Toft, Ulla; Kristoffersen, Lis; Ladelund, Steen;

    2008-01-01

    Few studies have investigated the specific effect of single intervention components in randomized controlled trials. The purpose was to investigate the effect of adding group-based diet and exercise counselling to individual life-style counselling on long-term changes in dietary habits....

  16. Does an eye-hand coordination test have added value as part of talent identification in table tennis? A validity and reproducibility study

    NARCIS (Netherlands)

    Faber, I.R.; Oosterveld, F.G.J.; Nijhuis-Van der Sanden, M.W.G.

    2014-01-01

    This study investigated the added value, i.e. discriminative and concurrent validity and reproducibility, of an eye-hand coordination test relevant to table tennis as part of talent identification. Forty-three table tennis players (7-12 years) from national (n = 13), regional (n = 11) and local trai

  17. On 1-loop diagrams in AdS space and the random disorder problem

    CERN Document Server

    Hung, Ling-Yan

    2010-01-01

    We study the complex scalar loop corrections to the boundary-boundary gauge two point function in pure AdS space in Poincare coordinates, in the presence of a boundary quadratic perturbation to the scalar. These perturbations correspond to double trace perturbations in the dual CFT and modify the boundary conditions of the bulk scalars in AdS. We find that, in addition to the usual UV divergences, the 1-loop calculation suffers from a divergence originating in the limit as the loop vertices approach the AdS horizon. We show that this type of divergence is independent of the boundary coupling, and making use of which we extract the finite relative variation of the imaginary part of the loop via Cutkosky rules as the boundary perturbation varies. Applying our methods to compute the effects of a time-dependent impurity to the conductivities using the replica trick in AdS/CFT, we find that generally an IR-relevant disorder reduces the conductivity and that in the extreme low frequency limit the correction due to ...

  18. The effect of adding group-based counselling to individual lifestyle counselling on changes in dietary intake. The Inter99 study – a randomized controlled trial

    OpenAIRE

    Smith Lisa; Pisinger Charlotta; Lau Cathrine; Ovesen Lars; Ladelund Steen; Kristoffersen Lis; Toft Ulla; Borch-Johnsen Knut; Jørgensen Torben

    2008-01-01

    Abstract Background Few studies have investigated the specific effect of single intervention components in randomized controlled trials. The purpose was to investigate the effect of adding group-based diet and exercise counselling to individual life-style counselling on long-term changes in dietary habits. Methods The study was a randomized controlled intervention study. From a general Danish population, aged 30 to 60 years (n = 61,301), two random sample were drawn (group A, n = 11,708; grou...

  19. Physical study of minced fish muscle with a white-grape by-product added as an ingredient.

    Science.gov (United States)

    Sánchez-Alonso, I; Solas, M T; Borderías, A J

    2007-03-01

    Functional properties of a white grape dietary fiber concentrate (WGDF) obtained from wine industry residues were determined with a view to their use as potential functional ingredient in seafood products. The main features of interest of WGDF are that it is a natural product containing high concentrations of dietary fiber (DF) with a high-soluble DF (sDF)/insoluble DF (iDF) ratio and associated bioactive compounds; as such it is considered potentially suitable for use as dietary fiber in the enrichment of foods. WGDF was therefore added to minced fish muscle (MFM) of horse mackerel (Trachurus trachurus) to take advantage of its technological properties, and also to enrich a food product that is a functional product in itself but does not contain dietary fiber. WGDF was added (2% and 4%) to MFM, which was stored for 6 mo at -20 degrees C, and a further lot was vacuum packed. Physical and mechanical properties, sensory and color analyses, microscopy, and electrophoretic profiles were all done in samples every month. The results indicate that WGDF had good functional properties, high water and oil retention capacity, and considerable swelling properties, which would make it useful as a natural ingredient in foods. The addition of WGDF to MFM augmented aggregation of myofibrillar proteins in the course of frozen storage, although electrophoretic profiles were very similar in samples with and without WGDF. The addition of WGDF to MFM made samples softer and less springy and cohesive. SEM showed good dispersion of WGDF in MFM but the matrix was more discontinuous than in the control. Water retention was significantly enhanced when WGDF was added, and the cooking yield improved. In sensory evaluation, samples containing 2% of WGDF scored highest in overall acceptance as compared with the control. Vacuum packing did not significantly affect the properties considered during frozen storage.

  20. AdS solutions through transgression

    Energy Technology Data Exchange (ETDEWEB)

    Donos, A. [Deutsches Elektronen-Synchrotron (DESY), Hamburg (Germany). Theory Group; Gauntlett, J.P. [Imperial College, London (United Kingdom). Blackett Lab.]|[Imperial College, London (United Kingdom). The Institute for Mathematical Sciences; Kim, Nakwoo [Kyung Hee Univ., Seoul (Korea). Dept. of Physics and Research Inst. of Basic Science

    2008-07-15

    We present new classes of explicit supersymmetric AdS{sub 3} solutions of type IIB supergravity with non-vanishing five-form flux and AdS{sub 2} solutions of D=11 supergravity with electric four-form flux. The former are dual to two-dimensional SCFTs with (0,2) supersymmetry and the latter to supersymmetric quantum mechanics with two supercharges. We also investigate more general classes of AdS{sub 3} solutions of type IIB supergravity and AdS{sub 2} solutions of D=11 supergravity which in addition have non-vanishing three-form flux and magnetic four-form flux, respectively. The construction of these more general solutions makes essential use of the Chern-Simons or ''transgression'' terms in the Bianchi identity or the equation of motion of the field strengths in the supergravity theories. We construct infinite new classes of explicit examples and for some of the type IIB solutions determine the central charge of the dual SCFTs. The type IIB solutions with non-vanishing three-form flux that we construct include a two-torus, and after two T-dualities and an S-duality, we obtain new AdS3 solutions with only the NS fields being non-trivial. (orig.)

  1. AD 病程中海马代谢水平与体积改变的研究%The study of hippocampal metabolites level and volumetric changes in AD

    Institute of Scientific and Technical Information of China (English)

    武文博; 刘任远; 张鑫; 朱斌; 张冰; 徐运

    2015-01-01

    hippocampus in Alzheimer disease (AD),mild cognitive impairment(MCI) and normal controls(NC).Methods: AD(n =20) and MCI(n=30) patients were recruited at the Memory Clinic of Neurology Department in Nanjing Drum Tower Hospital, and age-and sex-matched NC( n=30) were identified.MRI examinations were performed at 3 Tesla using an SENSE-8-channel phased array coil ( Achieva 3.0 T TX dual gradient and dual-source parallel RF excitation and transmission technology, Philips Medical Systems, The Netherlands).The structural MRI and 2D-PRESS 1H MRS data were acquired and preprocessed.Hippocampal volume was calculated by FreeSurFer.And the ratio of N-acetylaspartate ( NAA)/creatine( Cr) and myoinositol( mI)/Cr in hippocampal subfields ( head, body and tail) were calculated in Philips Work-station.The hippocampal volume and metabolite ratios were compared in AD, MCI and NC group. And correlation analysis between volume and metabolite ratios was also included in this study.Results: Bilateral hippocampal volumes were significantly reduced in AD compared with MCI and NC ( P0.05 ) .Compared with MCI and NC, NAA/Cr ratio in AD was significantly decreased in right hippocampus(head) and left hippocampus(head, body and tail ) , mI/Cr ratio in AD was significantly increased in left hippocampus ( head and tail ) and right hippocampus(head, body and tail)(P<0.05).Compared with NC, MCI patients showed significantly decreased NAA/Cr ratio and increased mI/Cr ratio in left hippocampus head ( P <0.05 ) .There were significant positive correlations between bilateral hippocampal volumes and MMSE, MoCA score( P<0.05) .Left hippocampal volume was positively correlated with NAA/Cr ratio and negatively correlated with mI/Cr ratio in left hippocampal head (P<0.05).Conclusion:Bilateral hippocampal volumes significantly reduce in AD.Hippocampal atrophy seems not obvious in MCI stage while changes of NAA/Cr and mI/Cr ratio in left hippocampal head could be detected, indicating that hippocampal metabolic changes

  2. Study on the added value of large-scale storage of electricity in the Netherlands; Onderzoek naar de toegevoegde waarde van grootschalige elektriciteitsopslag in Nederland

    Energy Technology Data Exchange (ETDEWEB)

    Boonekamp, P. [Amsterdam Power Exchange APX, Amsterdam (Netherlands); Bremmer, J. [Ministerie van Volkshuisvesting, Ruimtelijke Ordening en Milieu VROM, Den Haag (Netherlands); Doornbos, I.; Lukuna, E.; Otte, F. [Ministerie van Economische Zaken EZ, Den Haag (Netherlands); Droog, H. [Platform Duurzame Elektriciteitsvoorziening, Utrecht (Netherlands); De Jong, J. [Essent, Utrecht (Netherlands); Kling, W.; Pelgrum, E. [TenneT, Arnhem (Netherlands)

    2008-02-15

    This study compares the added value of five different techniques with an assumed base case with reference year 2020: Pump Accumulation Plant - Energy Island (PAC/EED); Underground pump accumulation Plant (OPAC); Compressed Air Energy Storage (CAES); utilizing storage capacity in Norwegian basins via a new NorNed connection; extra flexibility of electricity production in cogeneration units. This report provides answers to questions on: the influence of large scale energy storage on the environmental performance, economic efficiency and reliability of the Dutch electricity supply; How does large scale energy storage relate to the Western European electricity market; The need for the Dutch government to incentivise and facilitate the development of energy storage in the Dutch energy system. [mk]. [Dutch] In het onderzoek is de toegevoegde waarde van vijf verschillende technieken vergeleken met een veronderstelde base case met als zichtjaar 2020: Pomp Accumulatie Centrale - Energie-eiland (PAC/EE); Ondergrondse Pomp Accumulatie Centrale (OPAC); Compressed Air Energy Storage (CAES); benutten van opslagcapaciteit in Noorse waterbekkens via een nieuwe NorNed verbinding; extra flexibilisering van de elektriciteitsproductie bij warmtekracht eenheden. In dit rapport wordt antwoord gegeven op de vragen over: De invloed van grootschalige energieopslag op de milieuprestatie, economische efficientie en betrouwbaarheid van de Nederlandse elektriciteitsvoorziening; Hoe grootschalige energieopslag zich verhoudt tot de West-Europese elektriciteitsmarkt; De noodzaak voor de overheid om de ontwikkeling van energieopslag in het Nederlandse elektriciteitsvoorzieningsysteem te stimuleren en faciliteren.

  3. Stable isotope and trace element studies on gladiators and contemporary Romans from Ephesus (Turkey, 2nd and 3rd Ct. AD--mplications for differences in diet.

    Directory of Open Access Journals (Sweden)

    Sandra Lösch

    Full Text Available The gladiator cemetery discovered in Ephesus (Turkey in 1993 dates to the 2nd and 3rd century AD. The aim of this study is to reconstruct diverse diet, social stratification, and migration of the inhabitants of Roman Ephesus and the distinct group of gladiators. Stable carbon, nitrogen, and sulphur isotope analysis were applied, and inorganic bone elements (strontium, calcium were determined. In total, 53 individuals, including 22 gladiators, were analysed. All individuals consumed C3 plants like wheat and barley as staple food. A few individuals show indication of consumption of C4 plants. The δ13C values of one female from the gladiator cemetery and one gladiator differ from all other individuals. Their δ34S values indicate that they probably migrated from another geographical region or consumed different foods. The δ15N values are relatively low in comparison to other sites from Roman times. A probable cause for the depletion of 15N in Ephesus could be the frequent consumption of legumes. The Sr/Ca-ratios of the gladiators were significantly higher than the values of the contemporary Roman inhabitants. Since the Sr/Ca-ratio reflects the main Ca-supplier in the diet, the elevated values of the gladiators might suggest a frequent use of a plant ash beverage, as mentioned in ancient texts.

  4. Magnetic Field Effect on the Phase Transition in AdS Soliton Spacetime

    CERN Document Server

    Cai, Rong-Gen; Zhang, Hai-Qing; Zhang, Yun-Long

    2011-01-01

    We investigate the scalar perturbations in an AdS soliton background coupled to a Maxwell field via marginally stable modes. In the probe limit, we study the magnetic field effect on the holographic insulator/superconductor phase transition numerically and analytically. The condensate will be localized in a finite circular region for any finite constant magnetic field. Near the critical point, we find that there exists a simple relation among the critical chemical potential, magnetic field, the charge and mass of the scalar field. This relation indicates that the presence of the magnetic field causes the phase transition hard.

  5. Giant magnon on deformed AdS3×S3

    Science.gov (United States)

    Khouchen, Malak; KlusoÅ, Josef

    2014-09-01

    We study giant magnon solutions for strings moving on a deformed AdS3×S3 background. We impose a conformal gauge on the Polyakov action and proceed with solving the Virasoro constraints. The expressions of the conserved charge J and the energy of a single magnon excitation are then computed. Then we determine the dispersion relation of a giant magnon in the infinite J limit configuration and we find that for κ =0 it reduces to the celebrated Hofman-Maldacena dispersion relation.

  6. Giant Magnon on Deformed AdS(3)xS(3)

    CERN Document Server

    Khouchen, Malak

    2014-01-01

    We study giant magnon solutions for strings moving on a deformed AdS(3)xS(3) background. We impose a conformal gauge on the Polyakov action and proceed with solving the Virasoro constraints. The expressions of the conserved charge J and the energy of a single magnon excitation are then computed. Then we determine the dispersion relation in the infinite J limit configuration and we find that it reduces to celebrated Hofman-Maldacena dispersion relation when the deformation parameter goes to zero.

  7. STUDY ON THE THERAPEUTIC EFFECTS OF GINSENOSIDE Rg-1 AND GASTRODINE ON AD MODEL RATS INDUCED BY β-AMYLOID PEPTIDE (25-35)

    Institute of Scientific and Technical Information of China (English)

    2005-01-01

    Objective To study the therapeutic effects of Ginsenoside Rg-1 and Gastrodine on rats model of Alzheimer's disease(AD). Methods Aggregated β-Amyloid peptide (25-35) was injected into the lateral ventricle of rats to establish AD models. Ginsenoside Rg-1, Gastrodine and Ginsenoside Rg-1+Gastrodine were intraperitoneally injected into rats of each test group(Ginsenoside Rg-1∶10mg/kg·day; Gastrodine 100mg/kg·day) for 4 weeks, the rats of control group received equal volume of saline. Passive avoidance task and Morris maze test were done to assess the ability of learning and memory. The content of superoxide dismutase (SOD), malondiadehyde (MDA), total-antioxidative capability (T-AOC), Choline acetyltransferase (ChAT) and acetylcholinesterase (AchE) in brain tissue were measured. Results Ginsenoside Rg-1 and Gastrodine significantly improved learning and memory deficits in the rats with AD induced by β-Amyloid peptide (25-35) (P<0.05). Ginsenoside Rg-1+Gastrodine group were better than Ginsenoside Rg-1 group and Gastrodine group (P<0.05). Ginsenoside Rg-1 reduced the increase of SOD, MDA, but inhibited the decrease of T-AOC, AchE and ChAT; Gastrodine reduced the increase of SOD, MDA, while inhibited the decrease of T-AOC. Gastrodine could also prevent the activity of ChAT and AchE decline in AD rats. Conclusion Both Ginsenoside Rg-1 and Gastrodine have therapeutic effects on rats with AD; Ginsenoside Rg-1 and Gastrodine injection at the same time were better than only using one of them. Their mechanisms might different. Ginsenoside Rg-1 can not only inhibit peroxidation but also increase the activity of AchE and ChAT in brain tissue, while Gastrodine can inhibit peroxidation only, but it can't prevent the decline of ChAT and AchE activity in AD rats.

  8. Study of the pyrolysis of sludge and sludge/disposal filter cake mix for the production of value added products.

    Science.gov (United States)

    Velghe, Inge; Carleer, Robert; Yperman, Jan; Schreurs, Sonja

    2013-04-01

    Slow and fast pyrolysis of sludge and sludge/disposal filter cake (FC) mix are performed to investigate the liquid and solid products for their use as value added products. The obtained slow pyrolysis liquid products separate in an oil, a water rich fraction and a valuable crystalline solid 5,5-dimethyl hydantoin. During fast pyrolysis, mainly an oil fraction is formed. Aliphatic acids and amides present in the water rich fractions can be considered as value added products and could be purified. The oil fractions have properties which make them promising as fuel (25-35 MJ/kg, 14-20 wt% water content, 0.2-0.6 O/C value), but upgrading is necessary. Sludge/FC oils have a lower calorific value, due to evaporation of alcohols present in FC. ICP-AES analyses reveal that almost none of the metals present in sludge or sludge/FC are transferred towards the liquid fractions. The metals are enriched in the solid fractions.

  9. On modular properties of the AdS3 CFT

    CERN Document Server

    Baron, Walter

    2010-01-01

    We study modular properties of the AdS3 WZNW model. Although the Euclidean partition function is modular invariant, the characters on the Euclidean torus are ill-defined and their modular transformations are unknown. We reconsider the characters defined on the Lorentzian torus, focusing on their structure as distributions. We find a generalized S matrix, depending on the sign of the real modular parameters, which has two diagonal blocks and one off-diagonal block, mixing discrete and continuous representations, that we fully determine. We then explore the relations among the modular transformations, the fusion algebra and the boundary states. We explicitly construct Ishibashi states for the maximally symmetric D-branes and show that the generalized S matrix defines the one-point functions associated to point-like and H2 branes as well as the fusion rules of the degenerate representations of SL(2,R) appearing in the open string spectrum of the point-like D-branes, through a generalized Verlinde theorem.

  10. On Thermodynamical Behaviors of Kerr-Newman AdS Black Holes

    CERN Document Server

    Belhaj, A; Moumni, H El; Medari, L; Sedra, M B

    2013-01-01

    We reconsider the study of critical behaviors of Kerr-Newman AdS black holes in four dimensions. The study is made in terms of the moduli space parameterized by the charge Q and the rotation parameter a, relating the mass M of the black hole and its angular momentum J via the relation a=J/M. Specifically, we discuss such thermodynamical behaviors in the presence of a positive cosmological constant considered as a thermodynamic pressure and its conjugate quantity as a thermodynamic volume. The equation of state for a charged RN-AdS black hole predicts a critical universal number depending on the (Q,a) moduli space. In the vanishing limit of the a parameter, this prediction recovers the usual universal number in four dimensions. Then, we find the bounded regions of the moduli space allowing the consistency of the model with real thermodynamical variables.

  11. Analytical, ultrastructural, autoradiographic and biochemical studies on [3H]dicarboxylic acid added to cultures of melanoma cells.

    Science.gov (United States)

    Ward, B J; Breathnach, A S; Robins, E J; Bhasin, Y; Ethridge, L; Passi, S; Nazzaro-Porro, M

    1984-07-01

    Lentigo maligna and malignant melanoma can be treated by dicarboxylic acids (C9 and C12), which are competitive inhibitors of tyrosinase. We therefore studied the intracellular location and possible sites of action of dodecanedioic acid (C12) in murine melanoma cells, using EM autoradiography and biochemical analysis of lipid extracts by HPLC. Significant levels of radioactivity were found in the mitochondria and in the nuclei but not in association with membranes of rough endoplasmic reticulum, Golgi-associated endoplasmic reticulum, or Golgi apparatus, and not in coated vesicles or melanosomes. Biochemical analysis revealed that the diacid underwent beta-oxidation, which occurs only in mitochondria. The results suggest that the toxicity of dicarboxylic acids in melanoma cells is not related to anti-tyrosinase activity but may be due to interference with oxidoreductase enzymes in the mitochondria and possibly to inhibition of DNA synthesis in the nucleus.

  12. Adding Natural Areas to Social Indicators of Intra-Urban Health Inequalities among Children: A Case Study from Berlin, Germany

    Science.gov (United States)

    Kabisch, Nadja; Haase, Dagmar; Annerstedt van den Bosch, Matilda

    2016-01-01

    Research suggests that there is a relationship between the health of urban populations and the availability of green and water spaces in their daily environment. In this paper, we analyze the potential intra-urban relationships between children’s health determinants and outcomes and natural areas in Berlin, Germany. In particular, health indicators such as deficits in viso-motoric development in children are related to environmental indicators such as the natural area cover, natural area per capita and distance to natural areas; however, these indicators are also correlated with social determinants of health. The methodological approach used in this study included bivariate and multivariate analyses to explore the relations between health inequalities and social, socio-economic, and land use parameters. The results on a sub-district level indicated that there was a correlation between natural areas and social health determinants, both of which displayed a certain intra-urban spatial pattern. In particular, a lower percentage of natural area cover was correlated with deficits in viso-motoric development. However, results with percentage of natural area cover and per capita natural area with childhood overweight were not conclusive. No significant correlation was found for percentage of natural area cover and overweight, while significant negative correlation values were found between overweight and per capita natural area. This was identified particularly in the districts that had lower social conditions. On the other hand, the districts with the highest social conditions had the comparatively lowest levels of complete measles immunization. This study may facilitate public health work by identifying the urban areas in which the strengthening of health resources and actions should be prioritized and also calls for the inclusion of natural areas among the social health indicators included in intra-urban health inequality tools. PMID:27527197

  13. Adding Natural Areas to Social Indicators of Intra-Urban Health Inequalities among Children: A Case Study from Berlin, Germany.

    Science.gov (United States)

    Kabisch, Nadja; Haase, Dagmar; Annerstedt van den Bosch, Matilda

    2016-01-01

    Research suggests that there is a relationship between the health of urban populations and the availability of green and water spaces in their daily environment. In this paper, we analyze the potential intra-urban relationships between children's health determinants and outcomes and natural areas in Berlin, Germany. In particular, health indicators such as deficits in viso-motoric development in children are related to environmental indicators such as the natural area cover, natural area per capita and distance to natural areas; however, these indicators are also correlated with social determinants of health. The methodological approach used in this study included bivariate and multivariate analyses to explore the relations between health inequalities and social, socio-economic, and land use parameters. The results on a sub-district level indicated that there was a correlation between natural areas and social health determinants, both of which displayed a certain intra-urban spatial pattern. In particular, a lower percentage of natural area cover was correlated with deficits in viso-motoric development. However, results with percentage of natural area cover and per capita natural area with childhood overweight were not conclusive. No significant correlation was found for percentage of natural area cover and overweight, while significant negative correlation values were found between overweight and per capita natural area. This was identified particularly in the districts that had lower social conditions. On the other hand, the districts with the highest social conditions had the comparatively lowest levels of complete measles immunization. This study may facilitate public health work by identifying the urban areas in which the strengthening of health resources and actions should be prioritized and also calls for the inclusion of natural areas among the social health indicators included in intra-urban health inequality tools.

  14. HCMV AD169株大鼠慢性感染模型的初步探讨%An experimental study of rat infeected with human cytomegalovirus AD168 strain

    Institute of Scientific and Technical Information of China (English)

    孟红; 孙德刚; 王健; 刘菊华; 孙广莲; 李焱; 张家驹; 张维东

    2000-01-01

    Objective To Study the sensitivity of rat to human cytomegalovirus (HCMV) infection and to es-tablish a stable animal model. Methods Two kinds of rat experiments were carried out: 1)30 SD rats were divided intothree groups randomly,they were virus inoculated group,inactivated virus inoculated group and the normal rat group re-spectively; 2)40 Wistar rats were randomly divided into two groups,they were the virus inoculated group and the inacti-vated virus inoculated group. All the rats were inoculated through tail vein.90 d later,the rat's tissue lesions were ob-served by pathological techniques,HCMV antigen was detected by immunohistochemical method and the HCMV DNA wasanalyzed by in situ hybridization. Results The extensive pathological damages in tissues of HCMV infected rats wereobserved. Meanwhile,the viral antigen and viral DNA were also demonstrated in many tissues of HCMV infected rats.Conchusion Rat is sensitive to iridectiion of HCMV AD1168 strain, hut, as an animal model study,we stoll have a lot of works to do.%目的 探讨人巨细胞病毒(Human Cytomegalovirus,HCMV)感染大鼠的敏感性和稳定性,探讨建立大鼠感染HCMV动物模型的可行性。方法 第一次动物试验:SD大鼠30只,随机均分为3组,分别为接种病毒组、灭活病毒组和正常对照组,病毒接种途径为尾静脉注射;第二次动物试验:Wistar大鼠40只,分别为接种病毒组(20只)、灭活病毒组(20只),病毒接种途径同第一次动物试验。两次试验动物均于90d后分别以病理学方法 研究动物组织损伤特点,以免疫组化方法 检查病毒抗原,原位杂交方法 检测动物组织细胞中HCMV基因。结果 两次静脉途径接种HCMV AD169株90d的动物,组织发生广泛病理损害,免疫组化方法 和原位杂交方法 在多种组织细胞内查到HCMV抗原和基因表达。结论 HCMV AD169株可感染健康大鼠,可望作为HCMV动物慢性感染模型。

  15. Predicting AD conversion

    DEFF Research Database (Denmark)

    Liu, Yawu; Mattila, Jussi; Ruiz, Miguel �ngel Mu�oz

    2013-01-01

    To compare the accuracies of predicting AD conversion by using a decision support system (PredictAD tool) and current research criteria of prodromal AD as identified by combinations of episodic memory impairment of hippocampal type and visual assessment of medial temporal lobe atrophy (MTA) on MRI...

  16. Kolmogorov-Zakharov spectrum in AdS gravitational collapse.

    Science.gov (United States)

    de Oliveira, H P; Pando Zayas, Leopoldo A; Rodrigues, E L

    2013-08-01

    We study black hole formation during the gravitational collapse of a massless scalar field in asymptotically D-dimensional anti-de Sitter AdS(D) spacetimes for D = 4, 5. We conclude that spherically symmetric gravitational collapse in asymptotically AdS spaces is turbulent and characterized by a Kolmogorov-Zakharov spectrum. Namely, we find that after an initial period of weakly nonlinear evolution, there is a regime where the power spectrum of the Ricci scalar evolves as ω(-s) with the frequency, ω, and s ≈ 1.7 ± 0.1.

  17. Modeling MEA with the CPA equation of state: A parameter estimation study adding local search to PSO algorithm

    DEFF Research Database (Denmark)

    Santos, Letícia Cotia dos; Tavares, Frederico Wanderley; Ahón, Victor Rolando Ruiz;

    2015-01-01

    parameters for MEA. This work proposes adding LLE information systematically in the CPA parameter estimation procedure. At first, the parameter search space is defined by the results from the PSO sensitivity analysis for VLE considering the experimental error for vapor pressures and liquid densities...... (objective function cut off). Then, two possible methodologies are discussed: the first one uses all the possible parameter sets and check them against the LLE and VLE experimental data. The second method explicitly incorporates LLE information into the objective function and uses both PSO and PSO......-simplex hybrid algorithm to improve the convergence and refine the final solution. With this methodology it was possible to model simultaneously LLE and VLE. The CPA was then applied for a mixture containing cross-association (MEA-water) and the results show good agreement with experimental data indicating...

  18. Ts...sT transformation on $AdS_{5}\\times S^{5}$ background

    CERN Document Server

    Rashkov, R C; Yang, Y; Yang, Yi

    2005-01-01

    In this paper we consider a simple generalization of Lunin and Maldacena procedure of generating new string backgrounds based on TsT-transformations. We study multi-shift $Ts... sT$ transformations applied to backgrounds with at least two U(1) isometries. We prove that the string currents in any two backgrounds related by Ts...sT-transformations are equal. Performing this procedure to the $AdS_{5}\\times S^{5}$ we find a new background and study some properties of the semiclassical strings.

  19. Adding more value to added-value

    DEFF Research Database (Denmark)

    Marian, Livia

    regulation. The results of a qualitative concept test reveal positive attitudes towards the proposed production process. The discussions about fewer standards being sufficient or about options “in-between” conventional and organic standards indicate that the difference in production processes is noticed, yet...... it is probably valued less than expected. The added attributes need to be thoroughly considered when developing and marketing “organic plus” products, as their effect on other product characteristics (e.g. high prices) can detract from their added value....

  20. Probing crunching AdS cosmologies

    Science.gov (United States)

    Kumar, S. Prem; Vaganov, Vladislav

    2016-02-01

    Holographic gravity duals of deformations of CFTs formulated on de Sitter spacetime contain FRW geometries behind a horizon, with cosmological big crunch singularities. Using a specific analytically tractable solution within a particular single scalar truncation of {N}=8 supergravity on AdS4, we first probe such crunching cosmologies with spacelike radial geodesics that compute spatially antipodal correlators of large dimension boundary operators. At late times, the geodesics lie on the FRW slice of maximal expansion behind the horizon. The late time two-point functions factorise, and when transformed to the Einstein static universe, they exhibit a temporal non-analyticity determined by the maximal value of the scale factor ã max. Radial geodesics connecting antipodal points necessarily have de Sitter energy Ɛ ≲ ã max, while geodesics with Ɛ > ã max terminate at the crunch, the two categories of geodesics being separated by the maximal expansion slice. The spacelike crunch singularity is curved "outward" in the Penrose diagram for the deformed AdS backgrounds, and thus geodesic limits of the antipodal correlators do not directly probe the crunch. Beyond the geodesic limit, we point out that the scalar wave equation, analytically continued into the FRW patch, has a potential which is singular at the crunch along with complex WKB turning points in the vicinity of the FRW crunch. We then argue that the frequency space Green's function has a branch point determined by ã max which corresponds to the lowest quasinormal frequency.

  1. Pyrrolizidine alkaloids pyrrolams A-D: A survey of synthetic efforts, biological activity, and studies on their stability

    Digital Repository Service at National Institute of Oceanography (India)

    Majik, M.S.; Tilve, S.G.

    Pyrrolam A is a microbial metabolite, structurally related to plant alkaloids of the necine-type, and was isolated from the bacterial strain of Streptomyces olivaceus along with the related alkaloids pyrrolams B-D. The synthesis of (S)- and (R...

  2. Thermodynamics of Einstein-Proca AdS Black Holes

    CERN Document Server

    Liu, Hai-Shan; Pope, C N

    2014-01-01

    We study static spherically-symmetric solutions of the Einstein-Proca equations in the presence of a negative cosmological constant. We show that the theory admits solutions describing both black holes and also solitons in an asymptotically AdS background. Interesting subtleties can arise in the computation of the mass of the solutions and also in the derivation of the first law of thermodynamics. We make use of holographic renormalisation in order to calculate the mass, even in cases where the solutions have a rather slow approach to the asymptotic AdS geometry. By using the procedure developed by Wald, we derive the first law of thermodynamics for the black hole and soliton solutions. This includes a non-trivial contribution associated with the Proca "charge." The solutions cannot be found analytically, and so we make use of numerical integration techniques to demonstrate their existence.

  3. Universal isolation in the AdS landscape

    CERN Document Server

    Danielsson, U H; Vargas, S C

    2016-01-01

    We study the universal conditions for quantum non-perturbative stability against bubble nucleation for pertubatively stable AdS vacua based on positive energy theorems. We also compare our analysis with the pre-existing ones in the literature carried out within the thin-wall approximation. The aforementioned criterion is then tested in two explicit examples describing massive type IIA string theory compactified on $S^3$ and $S^3\\,\\times\\,S^3$, respectively. The AdS landscape of both classes of compactifications is known to consist of a set of isolated points. The main result is that all critical points respecting the Breitenlohner-Freedaman (BF) bound also turn out be stable at a non-perturbative level. Finally, we speculate on the possible universal features that may be extracted from the above specific examples.

  4. Perturbative entanglement thermodynamics for AdS spacetime: Renormalization

    CERN Document Server

    Mishra, Rohit

    2015-01-01

    We study the effect of charged excitations in the AdS spacetime on the first law of entanglement thermodynamics. It is found that `boosted' AdS black holes give rise to a more general form of first law which includes chemical potential and charge density. To obtain this result we have to resort to a second order perturbative calculation of entanglement entropy for small size subsystems. At first order the form of entanglement law remains unchanged even in the presence of charged excitations. But the thermodynamic quantities have to be appropriately `renormalized' at the second order due to the corrections. We work in the perturbative regime where $T_{thermal}\\ll T_E$.

  5. The Mixed Phase of Charged AdS Black Holes

    Directory of Open Access Journals (Sweden)

    Piyabut Burikham

    2016-01-01

    Full Text Available We study the mixed phase of charged AdS black hole and radiation when the total energy is fixed below the threshold to produce a stable charged black hole branch. The coexistence conditions for the charged AdS black hole and radiation are derived for the generic case when radiation particles carry charge. The phase diagram of the mixed phase is demonstrated for both fixed potential and charge ensemble. In the dual gauge picture, they correspond to the mixed phase of quark-gluon plasma (QGP and hadron gas in the fixed chemical potential and density ensemble, respectively. In the nuclei and heavy-ion collisions at intermediate energies, the mixed phase of exotic QGP and hadron gas could be produced. The mixed phase will condense and evaporate into the hadron gas as the fireball expands.

  6. Universal isolation in the AdS landscape

    Science.gov (United States)

    Danielsson, U. H.; Dibitetto, G.; Vargas, S. C.

    2016-12-01

    We study the universal conditions for quantum nonperturbative stability against bubble nucleation for pertubatively stable AdS vacua based on positive energy theorems. We also compare our analysis with the preexisting ones in the literature carried out within the thin-wall approximation. The aforementioned criterion is then tested in two explicit examples describing massive type IIA string theory compactified on S3 and S3×S3, respectively. The AdS landscape of both classes of compactifications is known to consist of a set of isolated points. The main result is that all critical points respecting the Breitenlohner-Freedman (BF) bound also turn out be stable at a nonperturbative level. Finally, we speculate on the possible universal features that may be extracted from the above specific examples.

  7. Effect of adding screening ultrasonography to screening mammography on patient recall and cancer detection rates: A retrospective study in Japan

    Energy Technology Data Exchange (ETDEWEB)

    Tohno, Eriko, E-mail: tohno@tmch.or.jp [Total Health Evaluation Center Tsukuba, 1-2, Amakubo, Tsukuba, Ibaraki 305-0005 (Japan); Umemoto, Takeshi, E-mail: umemoto@tmch.or.jp [Tsukuba Medical Center Hospital, 1-3-1, Amakubo, Tsukuba, Ibaraki 305-0005 (Japan); Sasaki, Kyoko, E-mail: kdon@za.cyberhome.ne.jp [Tsukuba Medical Center Hospital, 1-3-1, Amakubo, Tsukuba, Ibaraki 305-0005 (Japan); Morishima, Isamu, E-mail: morishima@tmch.or.jp [Tsukuba Medical Center Hospital, 1-3-1, Amakubo, Tsukuba, Ibaraki 305-0005 (Japan); Ueno, Ei, E-mail: e-ueno@tmch.or.jp [Tsukuba Medical Center Hospital, 1-3-1, Amakubo, Tsukuba, Ibaraki 305-0005 (Japan)

    2013-08-15

    Purpose: To determine whether adding screening ultrasonography to screening mammography can reduce patient recall rates and increase cancer detection rates. Materials and methods: We analyzed the results of mammography and ultrasonography breast screenings performed at the Total Health Evaluation Center Tsukuba, Japan, between April 2011 and March 2012. We also reviewed the modalities and results of diagnostic examinations from women with mammographic abnormalities who visited the Tsukuba Medical Center Hospital for further testing. Results: Of 11,753 women screened, cancer was diagnosed in 10 (0.22%) of the 4529 participants who underwent mammography alone, 23 (0.37%) of the 6250 participants who underwent ultrasonography alone, and 5 (0.51%) of the 974 participants who underwent mammography and ultrasonography. The recall rate due to mammographic abnormalities was 4.9% for women screened only with mammography and 2.6% for those screened with both modalities. The cancer detection rate was 0.22% for women screened only with mammography (positive predictive value, 4.5%) and 0.31% for those screened with both modalities (positive predictive value, 12.0%). Of the 211 lesions presenting as mammographic abnormalities investigated further, diagnostic ultrasonography found no abnormalities in 63 (29.9%) and benign findings in 69 (33.7%). The rest 36.4% needed mammography, cytological or histological examinations or follow-up in addition to diagnostic ultrasonography. Conclusions: It is possible to reduce the recall rate in screening mammography by combining mammography and ultrasonography for breast screening.

  8. Reconstructions of Circulation in the Northeastern Pacific and Western North America since 1500 A.D.: Relation to Precipitation and Fire Conditions in California

    Science.gov (United States)

    Zorita, Eduardo; Wahl, Eugene; Trouet, Valerie

    2016-04-01

    A reconstruction of the position of the North Pacific Jet Stream (NPJ) in wintertime over the past 500 years is. Reconstruction of NPJ behavior is driven by an analog process that employs existing paleoclimate field reconstructions of winter temperature, summer precipitation and summer soil moisture from western North America to select climate model states in millennial climate simulations that are closest to the field reconstructions. The skill of the reconstruction method is tested against the 20CR meteorological reanalysis. All three types of proxy sets individually contribute to the skill in the reconstruction of the winter atmospheric circulation. The NPJ reconstruction is also evaluated in relation to dry and wet extremes in California and extremes of Sierra Nevada fire activity. Results indicate that fire and precipitation extremes are both closely linked with NPJ winter position, with characteristic wet/low fire and dry/high fire NPJ spatial features in the northeastern Pacific adjacent to western North America. The meridional profiles of zonal wind at 200 hPa height can be classified according to winters belonging to dry and wet hydrological years and also according to summers with high or low fire activity. This classification indicates that in wet years and low-fire years the jet stream is more intense, more zonally oriented with peak winds occurring at lower latitudes. The opposite configuration occurs in dry, high-fire, years, with a more meandering jet stream peaking at higher latitudes. These features are in turn evaluated in future climate model scenarios using directly comparable transient integrations that cover the past millennium, the instrumental period, and the 21st century. Relatively wet/low fire regional conditions are reasonably possible in the later 21st century under a high greenhouse gas forcing regime (RCP 8.5), even though temperatures rise significantly. The implication of this combination of conditions in the Sierra Nevada is that

  9. The political attack ad

    Directory of Open Access Journals (Sweden)

    Palma Peña-Jiménez, Ph.D.

    2011-01-01

    Full Text Available During election campaigns the political spot has a clear objective: to win votes. This message is communicated to the electorate through television and Internet, and usually presents a negative approach, which includes a direct critical message against the opponent, rather than an exposition of proposals. This article is focused on the analysis of the campaign attack video ad purposely created to encourage the disapproval of the political opponent among voters. These ads focus on discrediting the opponent, many times, through the transmission of ad hominem messages, instead of disseminating the potential of the political party and the virtues and manifesto of its candidate. The article reviews the development of the attack ad since its first appearance, which in Spain dates back to 1996, when the famous Doberman ad was broadcast, and examines the most memorable campaign attack ads.

  10. Rationale and design of the AdRem study : Evaluating the effects of blood pressure lowering and intensive glucose control on vascular retinal disorders in patients with type 2 diabetes mellitus

    NARCIS (Netherlands)

    Stolk, Ronald P.; Vingerling, Johannes R.; Cruickshank, J. Kennedy; Hughes, Alun D.; Stanton, Alice; Lu Juming, [No Value; Patel, Anushka; Thom, Simon A. McG.; Grobbee, Diederick E.; Lu, J.M.

    2007-01-01

    The ADVANCE Retinal Measurements (AdRem) Study is a large intervention study evaluating the effects of target driven intensive glucose control and placebo controlled blood pressure lowering on retinal vascular changes. AdRem is a sub-study of the ADVANCE Study (Action in Diabetes and Vascular diseas

  11. A peptidomic approach to study the contribution of added casein proteins to the peptide profile in Spanish dry-fermented sausages.

    Science.gov (United States)

    Mora, Leticia; Escudero, Elizabeth; Aristoy, M-Concepción; Toldrá, Fidel

    2015-11-06

    Peptidomics is a necessary alternative in the analysis of naturally generated peptides in dry-fermented processing. The intense proteolysis occurred during the processing of dry-fermented sausages is due to the action of endopeptidases and exopeptidases from both, endogenous muscle origin and lactic acid bacteria (LAB) added in the starter. Sodium caseinate is frequently used as an additive in this type of products because of its emulsifying properties, and consequently influences the protein profile available during the proteolysis. In this study, a mass spectrometry approach has been used to determine the impact of added sodium caseinate in the final peptide profile as well as to analyse its possible influence in the presence of certain previously described casein-derived bioactive peptides.

  12. 基于ADS-B的便携式空情侦测系统技术方案研究%Study of the Portable Air Situation Detection System Technological Program on ADS-B

    Institute of Scientific and Technical Information of China (English)

    孟军; 马彦恒; 董健; 任新涛

    2012-01-01

    针对目前雷达训练缺乏调度,难以检验训练效果的问题,通过分析广播式自动相关监视(ADS-B)的技术特点,提出基于ADS-B的便携式空情侦测系统的总体技术方案,并对其关键技术进行阐述.该系统通过侦收民航飞机广播的高精度目标参数,实现空情监视,提供指挥员进行训练调度;通过比对雷达测量结果,检验训练效果.%As the radar training is lack of scheduling currently and the difficulty to test the training effect .by analyzing the technical characteristics of the Automatic Dependent Surveillance-Broadcast(ADS-B) .proposing the overall technical program of the portable air situation detection system on ADS-B and elaborating its key technologies. The system achieves the air situation monitoring and guides the commander to make traning schedule through detecing and receiving the high-precision target parameters broadcasted by civil aircraft. By comparing the results of radar measurement to test the training results.

  13. Wireless Ad Hoc Networks

    Directory of Open Access Journals (Sweden)

    Hong-Chuan Yang

    2007-01-01

    Full Text Available We study the energy-efficient configuration of multihop paths with automatic repeat request (ARQ mechanism in wireless ad hoc networks. We adopt a cross-layer design approach and take both the quality of each radio hop and the battery capacity of each transmitting node into consideration. Under certain constraints on the maximum tolerable transmission delay and the required packet delivery ratio, we solve optimization problems to jointly schedule the transmitting power of each transmitting node and the retransmission limit over each hop. Numerical results demonstrate that the path configuration methods can either significantly reduce the average energy consumption per packet delivery or considerably extend the average lifetime of the multihop route.

  14. Causality and the conformal boundary of AdS in real-time holography

    CERN Document Server

    Enciso, Alberto

    2012-01-01

    We consider the holographic prescription problem in a (Lorentzian) AdS background, deriving from first principles the explicit formulas that relate the field at infinity with the field in the bulk. In contrast with the previous studies of the "real-time" holography problem, our derivation uses purely classical arguments that involve causality, as in the usual treatment of the holographic prescription problem in Wick-rotated spaces of Euclidean signature. We show that there is a unique propagator that preserves causality and see that this provides a simple picture of the relationship between the bulk manifold and its conformal boundary.

  15. Probing crunching AdS cosmologies

    CERN Document Server

    Kumar, S Prem

    2015-01-01

    Holographic gravity duals of deformations of CFTs formulated on de Sitter spacetime contain FRW geometries behind a horizon, with cosmological big crunch singularities. Using a specific analytically tractable solution within a particular single scalar truncation of N=8 supergravity on AdS_4, we first probe such crunching cosmologies with spacelike radial geodesics that compute spatially antipodal correlators of large dimension boundary operators. At late times, the geodesics lie on the FRW slice of maximal expansion behind the horizon. The late time two-point functions factorise, and when transformed to the Einstein static universe, they exhibit a temporal non-analyticity determined by the maximal value of the scale factor a_{max} . Radial geodesics connecting antipodal points necessarily have de Sitter energy E \\leq a_{max}, while geodesics with E > a_{max} terminate at the crunch, the two categories of geodesics being separated by the maximal expansion slice. The spacelike crunch singularity is curved "outw...

  16. Twistor methods for AdS$_5$

    CERN Document Server

    Adamo, Tim; Williams, Jack

    2016-01-01

    We consider the application of twistor theory to five-dimensional anti-de Sitter space. The twistor space of AdS$_5$ is the same as the ambitwistor space of the four-dimensional conformal boundary; the geometry of this correspondence is reviewed for both the bulk and boundary. A Penrose transform allows us to describe free bulk fields, with or without mass, in terms of data on twistor space. Explicit representatives for the bulk-to-boundary propagators of scalars and spinors are constructed, along with twistor action functionals for the free theories. Evaluating these twistor actions on bulk-to-boundary propagators is shown to produce the correct two-point functions.

  17. Holography of AdS vacuum bubbles

    Energy Technology Data Exchange (ETDEWEB)

    Barbon, J.L.F. [Instituto de Fisica Teorica IFT UAM/CSIC, Cantoblanco, Madrid 28049 (Spain); Rabinovici, E. [Racah Institute of Physics, Hebrew University, Jerusalem 91904 (Israel)

    2011-07-15

    We consider the fate of AdS vacua connected by tunneling events. A precise holographic dual of thin-walled Coleman-de Luccia bounces is proposed in terms of Fubini instantons in an unstable CFT. This proposal is backed by several qualitative and quantitative checks, including the precise calculation of the instanton action appearing in evaluating the decay rate. Big crunches manifest themselves as time dependent processes which reach the boundary of field space in a finite time. The infinite energy difference involved is identified on the boundary and highlights the ill-defined nature of the bulk setup. We propose a qualitative scenario in which the crunch is resolved by stabilizing the CFT, so that all attempts at crunching always end up shielded from the boundary by the formation of black hole horizons. In all these well defined bulk processes the configurations have the same asymptotics and are finite energy excitations.

  18. Comparison of two commonly practiced atropinization regimens in acute organophosphorus and carbamate poisoning, doubling doses vs. ad hoc: a prospective observational study.

    Science.gov (United States)

    Perera, P M S; Shahmy, S; Gawarammana, I; Dawson, A H

    2008-06-01

    There is a wide variation and lack of evidence in current recommendations for atropine dosing schedules leading to subsequent variation in clinical practice. Therefore, we sought to examine the safety and effectiveness of a titrated vs. ad hoc atropine treatment regimen in a cohort of patients with acute cholinesterase inhibitor pesticide poisoning. A prospective cohort study was conducted in three district secondary referral hospitals in Sri Lanka using a structured data collection form that collected details of clinical symptoms and outcomes of cholinesterase inhibitor pesticide poisoning, atropine doses, and signs of atropinization. We compared two hospitals that used a titrated dosing protocol based on a structured monitoring sheet for atropine infusion with another hospital using an ad hoc regime. During the study, 272 symptomatic patients with anticholinesterase poisoning requiring atropine were admitted to the three hospitals. Outcomes of death and ventilation were analyzed for all patients, 226 patients were prospectively assessed for atropine toxicity. At baseline, patients in the titrated dose cohort had clinical signs consistent with greater toxicity. This in part may be due to ingestion of more toxic organophosphates. They received less pralidoxime and atropine, and were less likely to develop features of atropine toxicity, such as delirium (1% vs. 17%), hallucinations (1% vs. 35%), or either (1% vs. 35%) and need for patient restraint (3% vs. 48%) compared with the ad hoc dose regime. After adjusting for the pesticides ingested, there was no difference in mortality and ventilatory rates between protocols. Ad hoc high dose atropine regimens are associated with more frequent atropine toxicity without any obvious improvement in patient outcome compared with doses titrated to clinical effect. Atropine doses should be titrated against response and toxicity. Further education and the use of a structured monitoring sheet may assist in more appropriate

  19. Joule-Thomson expansion of the charged AdS black holes

    Science.gov (United States)

    Ökcü, Özgür; Aydıner, Ekrem

    2017-01-01

    In this paper, we study Joule-Thomson effects for charged AdS black holes. We obtain inversion temperatures and curves. We investigate similarities and differences between van der Waals fluids and charged AdS black holes for the expansion. We obtain isenthalpic curves for both systems in the T- P plane and determine the cooling-heating regions.

  20. Joule-Thomson Expansion of Charged AdS Black Holes

    CERN Document Server

    Ökcü, Özgür

    2016-01-01

    In this paper, we study Joule-Thomson effects for charged AdS black holes. We obtain inversion temperatures and curves. We investigate similarities and differences between van der Waals fluids and charged AdS black holes for the expansion. We obtain isenthalpic curves for both systems in $T-P$ plane and determine the cooling-heating regions.

  1. Effects of ad placement and type on consumer responses to podcast ads.

    Science.gov (United States)

    Ritter, Eric A; Cho, Chang-Hoan

    2009-10-01

    The purpose of this study was to understand the effects of podcast ad placement and podcast ad type on consumers' perceived intrusiveness, perceived irritation, attitude toward the ad, and ad avoidance. Our 2 x 2 (traditional ad vs. sponsorship by beginning vs. middle) experimental study found that sponsorships generated better consumer responses than did traditional ads and that podcast ads placed at the beginning of audio podcasts yielded better consumer responses than those placed in the middle. Implications for marketers and advertisers are discussed.

  2. Stringy Membranes in AdS/CFT

    CERN Document Server

    Axenides, Minos; Linardopoulos, Georgios

    2013-01-01

    We study membrane configurations in AdS_{7/4}xS^{4/7}. The membranes are wrapped around the compact manifold S^{4/7} and are dynamically equivalent to bosonic strings in AdS_5. We thus conveniently identify them as "stringy membranes". For the case of AdS_7xS^4, their construction is carried out by embedding the Polyakov action for classical bosonic strings in AdS_5, into the corresponding membrane action. Therefore, every string configuration in AdS_5 can be realized by an appropriately chosen stringy membrane in AdS_7xS^4. We discuss the possibility of this being also the case for stringy membranes in AdS_4xS^7/Z^k (k > 1 or k = 1). By performing a stability analysis to the constructed solutions, we find that the (membrane) fluctuations along their transverse directions are organized in multiple Lam\\'{e} stability bands and gaps in the space of parameters of the configurations. In this membrane picture, strings exhibit a single band/gap structure. Since the spectrum of quadratic fluctuations is important fo...

  3. Upregulated GABA inhibitory function in AD/HD children with Child Behavior Checklist–Dysregulation Profile: 123I-iomazenil SPECT study

    Directory of Open Access Journals (Sweden)

    Shinichiro eNagamitsu

    2015-06-01

    Full Text Available The Child Behavior Checklist–Dysregulation Profile (CBCL-DP refers to a pattern of elevated scores on the Attention Problems, Aggression, and Anxiety/Depression subscales of the Child Behavior Checklist. The aim of the present study was to investigate the potential role of GABA inhibitory neurons in children with attention deficit/hyperactivity disorder (AD/HD and dysregulation assessed with a dimensional measure. Brain single photon emission computed tomography (SPECT was performed in 35 children with AD/HD using 123I-iomazenil, which binds with high affinity to benzodiazepine receptors. Iomazenil binding activities were assessed with respect to the presence or absence of a threshold CBCL-DP (a score ≥210 for the sum of the three subscales Attention Problems, Aggression, and Anxiety/Depression. We then attempted to identify which CBCL-DP subscale explained the most variance with respect to SPECT data, using age, sex, and history of maltreatment as covariates. Significantly higher iomazenil binding activity was seen in the posterior cingulate cortex (PCC of AD/HD children with a significant CBCL-DP. The Anxiety/Depression subscale on the CBCL had significant effects on higher iomazenil binding activity in the left superior frontal, middle frontal, and temporal regions, as well as in the PCC. The present brain SPECT findings suggest that GABAergic inhibitory neurons may play an important role in the neurobiology of the CBCL-DP, in children with ADHD.

  4. Skil problemerne ad

    DEFF Research Database (Denmark)

    Kaspersen, Peter

    2007-01-01

    På grundlag af evalueringer og forskning i gymnasiereformen 2005 foreslås det at skille problemerne ad i forskellige niveauer. Herved kan der arbejdes med niveaudelte løsninger.......På grundlag af evalueringer og forskning i gymnasiereformen 2005 foreslås det at skille problemerne ad i forskellige niveauer. Herved kan der arbejdes med niveaudelte løsninger....

  5. Relating the Curriculum Study to Staff Development.

    Science.gov (United States)

    Clarke, Robert; Snow, Gordon

    Staff development is a school district activity that is generating more activity and becoming more expensive. As the amount of dollars spent increases, so will the demands for accountability and results. Traditional methods for determining staff development programs are inadequate or incomplete. A more effective method is to relate the staff…

  6. Catalog of NASA-Related Case Studies

    Data.gov (United States)

    National Aeronautics and Space Administration — The OCKO has developed over 50 case studies to enhance learning at workshops, training, retreats and conferences. Case studies make mission knowledge attractive and...

  7. 76 FR 44933 - Determination on Adding Cancer, or a Certain Type of Cancer, to the List of WTC-Related Health...

    Science.gov (United States)

    2011-07-27

    ... Disease Control and Prevention (CDC) announces the availability of the ``First Periodic Review of... first periodic Review of Cancer for the WTC Health Program, insufficient evidence exists at this time to...-Related Health Conditions AGENCY: National Institute for Occupational Safety and Health (NIOSH) of...

  8. Varying Overhead Ad Hoc on Demand Vector Routing in Highly Mobile Ad Hoc Network

    Directory of Open Access Journals (Sweden)

    V. Balaji

    2011-01-01

    Full Text Available Problem statement: An inherent feature of mobile ad hoc networks is the frequent change of network topology leading to stability and reliability problems of the network. Highly dynamic and dense network have to maintain acceptable level of service to data packets and limit the network control overheads. This capability is closely related as how quickly the network protocol control overhead is managed as a function of increased link changes. Dynamically limiting the routing control overheads based on the network topology improves the throughput of the network. Approach: In this study we propose Varying Overhead - Ad hoc on Demand Vector routing protocol (VO-AODV for highly dynamic mobile Ad hoc network. The VO-AODV routing protocol proposed dynamically modifies the active route time based on the network topology. Results and Conclusion: Simulation results prove that the proposed model decreases the control overheads without decreasing the QOS of the network.

  9. A note on bulk locality and covariance in AdS/CFT

    CERN Document Server

    Emelyanov, Slava

    2015-01-01

    This paper studies a recently proposed relation between the emergence of bulk locality in AdS/CFT and the theory of quantum error correction. We show that if this relation is indeed realized in AdS/CFT, then bulk covariance is broken in the semi-classical limit.

  10. Yangian symmetry, S-Matrices and Bethe Ansats for the Ads5 x S5 superstring

    NARCIS (Netherlands)

    de Leeuw, M.

    2009-01-01

    We discuss the relation between the recently derived bound state S-matrices for the AdS5× S5 superstring and Yangian symmetry. We will study the relation between this Yangian symmetry and the Bethe ansatz. In particular we can use it to derive the Bethe equations for bound states.

  11. Experimental study of relative, turbulent diffusion

    DEFF Research Database (Denmark)

    Mann, J.; Ott, Søren; Andersen, J.S.

    1999-01-01

    tank with two oscillating grids generating turbulence. In the experiments reported here we have obtained Reynolds numbers based on Taylor's microscale ofabout one hundred. The PT system, which is also described in this report, consists of four CCD cameras, a synchronous light source and a recording...... system with two computers each equipped with a frame grabber card. In the search for the best experimentalmethods we have revised the concept of local homogeneity and derived a law for the velocity--acceleration structure function. A second by-product of this effort is a relatively simple derivation...

  12. Automated Experiments on Ad Privacy Settings

    Directory of Open Access Journals (Sweden)

    Datta Amit

    2015-04-01

    Full Text Available To partly address people’s concerns over web tracking, Google has created the Ad Settings webpage to provide information about and some choice over the profiles Google creates on users. We present AdFisher, an automated tool that explores how user behaviors, Google’s ads, and Ad Settings interact. AdFisher can run browser-based experiments and analyze data using machine learning and significance tests. Our tool uses a rigorous experimental design and statistical analysis to ensure the statistical soundness of our results. We use AdFisher to find that the Ad Settings was opaque about some features of a user’s profile, that it does provide some choice on ads, and that these choices can lead to seemingly discriminatory ads. In particular, we found that visiting webpages associated with substance abuse changed the ads shown but not the settings page. We also found that setting the gender to female resulted in getting fewer instances of an ad related to high paying jobs than setting it to male. We cannot determine who caused these findings due to our limited visibility into the ad ecosystem, which includes Google, advertisers, websites, and users. Nevertheless, these results can form the starting point for deeper investigations by either the companies themselves or by regulatory bodies.

  13. Mobile ad hoc networking

    CERN Document Server

    John Wiley & Sons

    2004-01-01

    "Assimilating the most up-to-date information on research and development activities in this rapidly growing area, Mobile Ad Hoc Networking covers physical, data link, network, and transport layers, as well as application, security, simulation, and power management issues in sensor, local area, personal, and mobile ad hoc networks. Each of the book's sixteen chapters has been written by a top expert and discusses in-depth the most important topics in the field. Mobile Ad Hoc Networking is an excellent reference and guide for professionals seeking an in-depth examination of topics that also provides a comprehensive overview of the current state-of-the-art."--Jacket.

  14. Real Time Study and Related Variables

    Institute of Scientific and Technical Information of China (English)

    WU Xiao-qing

    2016-01-01

    This paper first, illustrates the advantages of applying real time study to linguistic researches. Second, this paper also compares linguistic variables with linguistic variant; nasality, stronger constraint and weaker constraint have been clearly de-fined as well.

  15. Impairment of blood brain barrier is related with the neuroinflammation induced peripheral immune status in intracerebroventricular colchicine injected rats: An experimental study with mannitol.

    Science.gov (United States)

    Sil, Susmita; Ghosh, Arijit; Ghosh, Tusharkanti

    2016-09-01

    The neurodegeneration in AD patients may be associated with changes of peripheral immune responses. Some peripheral immune responses are altered due to neuroinflammation in colchicine induced AD (cAD) rats. The leaky blood brain barrier (BBB) in cAD-rats may be involved in inducing peripheral inflammation, though there is no report in this regard. Therefore, the present study was designed to investigate the role of BBB in cADrats by altering the BBB in a time dependent manner with injection (i.v.) of mannitol (BBB opener). The inflammatory markers in the brain and serum along with the peripheral immune responses were measured after 30 and 60min of mannitol injection in cAD rats. The results showed higher inflammatory markers in the hippocampus and serum along with alterations in peripheral immune parameters in cAD rats. Although the hippocampal inflammatory markers did not further change after mannitol injection in cAD rats, the serum inflammatory markers and peripheral immune responses were altered and these changes were greater after 60min than that of 30min of mannitol injection. The present study shows that the peripheral immune responses in cAD rats after 30 and 60min of mannitol injection are related to magnitude of impairment of BBB in these conditions. It can be concluded from this study that impairment of BBB in cAD rats is related to the changes of peripheral immune responses observed in that condition.

  16. Adding Learning Resources: A Study of Two Toddlers' Modes and Trajectories of Participation in Early Childhood Education

    Science.gov (United States)

    Kultti, Anne

    2015-01-01

    This study focuses on the nature of children's participation in an Australian early childhood context in which their second language is used. The aim is to create knowledge of toddlers' modes and trajectories of participation. Empirical data documenting the participation of two toddlers were gathered through video observations of everyday…

  17. Adding International Themes to a Community College Curriculum: A Review of the Southwest Consortium for International Studies and Foreign Languages.

    Science.gov (United States)

    Wallace, Steve

    1989-01-01

    Describes a program designed by Pima Community College (Arizona) and funded by the U. S. Department of Education. Discusses the establishment of a consortium of two-and four-year colleges committed to developing international studies curricula. Examines the use of workshops and mini-grants. Provides examples of courses and modules which were…

  18. A Study of the Value Added by Transformational Leadership Practices to Teachers' Job Satisfaction and Organizational Commitment

    Science.gov (United States)

    Kieres, Katherine H.; Gutmore, Daniel

    2014-01-01

    Based on Bass and Riggio's (2006) Augmentation Model of Transactional and Transformational Leadership, this quantitative study sought to identify the amount of variance in teacher job satisfaction and organizational commitment that can be explained by principals' transformational leadership behaviors, above and beyond the influence of…

  19. Reentrant Phase Transitions in Rotating AdS Black Holes

    CERN Document Server

    Altamirano, Natacha; Mann, Robert B

    2013-01-01

    We study the thermodynamics of higher-dimensional singly spinning asymptotically AdS black holes in the canonical (fixed J) ensemble of extended phase space, where the cosmological constant is treated as pressure and the corresponding conjugate quantity is interpreted as thermodynamic volume. Along with the usual small/large black hole phase transition, we find a new phenomenon of reentrant phase transitions for all d>5 dimensions, in which a monotonic variation of the temperature yields two phase transitions from large to small and back to large black holes. This situation is similar to that seen in multicomponent liquids.

  20. Heavy quark potential from deformed AdS5 models

    Science.gov (United States)

    Zhang, Zi-qiang; Hou, De-fu; Chen, Gang

    2017-04-01

    In this paper, we investigate the heavy quark potential in some holographic QCD models. The calculation relies on a modified renormalization scheme mentioned in a previous work of Albacete et al. After studying the heavy quark potential in Pirner-Galow model and Andreev-Zakharov model, we extend the discussion to a general deformed AdS5 case. It is shown that the obtained potential is negative definite for all quark-antiquark separations, differs from that using the usual renormalization scheme.

  1. A comparative study of the effect of caudal dexmedetomidine versus morphine added to bupivacaine in pediatric infra-umbilical surgery

    Directory of Open Access Journals (Sweden)

    Hossam A El Shamaa

    2014-01-01

    Full Text Available Background: One of the most commonly used regional anesthetic techniques in pediatric surgeries is the caudal epidural block. Its main disadvantage remains the short duration of action. Hence, different additives have been used. Dexmedetomidine is a potent as well as highly selective α2 adrenergic receptor agonist. The aim of this randomized, double-blinded, study was to compare the duration of postoperative analgesia of caudal dexmedetomidine versus morphine in combination with bupivacaine in pediatric patients undergoing lower abdominal or perineal surgery. Patients and Methods: A total of 50 pediatric patients 1-5 years old The American Society of Anesthesiologists status I, II scheduled for lower abdominal and perineal surgeries were included in the study. The patients were enrolled into 2 equal groups: Group A patients (n = 25 received dexmedetomidine with bupivacaine while Group B patients (n = 25 received morphine with bupivacaine. Patients were placed in a supine position then inhalational general anesthesia was induced, and laryngeal mask airway (LMA was placed. Patients were then given caudal epidural analgesia. By the end of surgery reversal of muscle relaxation was done and the LMA was removed. Post-operatively, the sedation as well as pain score were observed and recorded. Results: The current study showed that minor complications were recorded in the post-anesthesia care unit; in addition, significantly longer periods of analgesia and sedation were detected in Group A. However, no significant differences in demographic data, as well as in the duration of surgery, and the time of emergence from anesthesia and patient condition during recovery were detected. Conclusion: The present study suggested that use of dexmedetomidine, during single dose injection, as an additive to the local anesthetic bupivacaine in caudal epidural analgesia prolongs the duration of post-operative analgesia following lower abdominal as well as perineal

  2. Euclidean Wilson loops and Minimal Area Surfaces in Minkowski AdS3

    CERN Document Server

    Irrgang, Andrew

    2015-01-01

    The AdS/CFT correspondence relates Wilson loops in N=4 SYM theory to minimal area surfaces in AdS5xS5 space. If the Wilson loop is Euclidean and confined to a plane (t,x) then the dual surface is Euclidean and lives in Minkowski AdS3. In this paper we study such minimal area surfaces generalizing previous results obtained in the Euclidean case. Since the surfaces we consider have the topology of a disk, the holonomy of the flat current vanishes which is equivalent to the condition that a certain boundary Schroedinger equation has all its solutions anti-periodic. If the potential for that Schroedinger equation is found then reconstructing the surface and finding the area become simpler. In particular we write a formula for the Area in terms of the Schwarzian derivative of the contour. Finally an infinite parameter family of analytical solutions using Riemann Theta functions is described. In this case, both the area and the shape of the surface are given analytically and used to check the previous results.

  3. Antiproton-Decelerator (AD)

    CERN Multimedia

    Laurent Guiraud

    1998-01-01

    When the Low-Energy Antiproton Ring (LEAR) was stopped in 1996, because of its costly operation, a cheaper way of continuing low-energy antiproton physics was sought. The Antiproton-Collector (AC), added in 1987 to the Antiproton Accumulator (AA) to provide a tenfold intensity increase, was converted into the Antiproton-Decelerator (AD). Antiprotons from the target at 3.5 GeV/c are decelerated to 100 MeV/c, and fast-ejected to the experiments. Major changes were necessary. Above all, the conversion from a constant-field machine to one with a magnetic cycle, modulating the field by an impressive factor 35. New systems for stochastic and electron cooling had to be added. Beam diagnostics at an intensity of only 2E7 antiprotons was a challenge. In 2000, the AD began delivery of antiprotons to the experiments.

  4. The FORCE Fitness Profile--Adding a Measure of Health-Related Fitness to the Canadian Armed Forces Operational Fitness Evaluation.

    Science.gov (United States)

    Gagnon, Patrick; Spivock, Michael; Reilly, Tara; Mattie, Paige; Stockbrugger, Barry

    2015-11-01

    In 2013, the Canadian Armed Forces (CAF) implemented the Fitness for Operational Requirements of Canadian Armed Forces Employment (FORCE), a field expedient fitness test designed to predict the physical requirements of completing common military tasks. Given that attaining this minimal physical fitness standard may not represent a challenge to some personnel, a fitness incentive program was requested by the chain of command to recognize and reward fitness over and above the minimal standard. At the same time, it was determined that the CAF would benefit from a measure of general health-related fitness, in addition to this measure of operational fitness. The resulting incentive program structure is based on gender and 8 age categories. The results on the 4 elements of the FORCE evaluation were converted to a point scale from which normative scores were derived, where the median score corresponds to the bronze level, and silver, gold, and platinum correspond to a score which is 1, 2, and 3 SDs above this median, respectively. A suite of rewards including merit board point toward promotions and recognition on the uniform and material rewards was developed. A separate group rewards program was also tabled, to recognize achievements in fitness at the unit level. For general fitness, oxygen capacity was derived from FORCE evaluation results and combined with a measure of abdominal circumference. Fitness categories were determined based on relative risks of mortality and morbidity for each age and gender group. Pilot testing of this entire program was performed with 624 participants to assess participants' reactions to the enhanced test, and also to verify logistical aspects of the electronic data capture, calculation, and transfer system. The newly dubbed fitness profile program was subsequently approved by the senior leadership of the CAF and is scheduled to begin a phased implementation in June 2015.

  5. Bioenergetic flux, mitochondrial mass and mitochondrial morphology dynamics in AD and MCI cybrid cell lines.

    Science.gov (United States)

    Silva, Diana F; Selfridge, J Eva; Lu, Jianghua; E, Lezi; Roy, Nairita; Hutfles, Lewis; Burns, Jeffrey M; Michaelis, Elias K; Yan, ShiDu; Cardoso, Sandra M; Swerdlow, Russell H

    2013-10-01

    Bioenergetic dysfunction occurs in Alzheimer's disease (AD) and mild cognitive impairment (MCI), a clinical syndrome that frequently precedes symptomatic AD. In this study, we modeled AD and MCI bioenergetic dysfunction by transferring mitochondria from MCI, AD and control subject platelets to mtDNA-depleted SH-SY5Y cells. Bioenergetic fluxes and bioenergetics-related infrastructures were characterized in the resulting cytoplasmic hybrid (cybrid) cell lines. Relative to control cybrids, AD and MCI cybrids showed changes in oxygen consumption, respiratory coupling and glucose utilization. AD and MCI cybrids had higher ADP/ATP and lower NAD+/NADH ratios. AD and MCI cybrids exhibited differences in proteins that monitor, respond to or regulate cell bioenergetic fluxes including HIF1α, PGC1α, SIRT1, AMPK, p38 MAPK and mTOR. Several endpoints suggested mitochondrial mass increased in the AD cybrid group and probably to a lesser extent in the MCI cybrid group, and that the mitochondrial fission-fusion balance shifted towards increased fission in the AD and MCI cybrids. As many of the changes we observed in AD and MCI cybrid models are also seen in AD subject brains, we conclude reduced bioenergetic function is present during very early AD, is not brain-limited and induces protean retrograde responses that likely have both adaptive and mal-adaptive consequences.

  6. AdS_3: the NHEK generation

    CERN Document Server

    Bena, Iosif; Puhm, Andrea

    2015-01-01

    It was argued in arXiv:1203.4227 that the five-dimensional near-horizon extremal Kerr (NHEK) geometry can be embedded in String Theory as the infrared region of an infinite family of non-supersymmetric geometries that have D1, D5, momentum and KK monopole charges. We show that there exists a method to embed these geometries into asymptotically-AdS_3 x S^3/Z_N solutions, and hence to obtain infinite families of flows whose infrared is NHEK. This indicates that the CFT dual to the NHEK geometry is the IR fixed point of a Renormalization Group flow from a known local UV CFT and opens the door to its explicit construction.

  7. Shapes related to longitudinal studies of disease

    DEFF Research Database (Denmark)

    Erleben, Lene Lillemark

    . The first part of this dissertation studies the growth patterns of atherosclerotic calcified deposits in the lumbar aorta based on x-ray images over an 8-year time period. We have been able to find simple growth patterns that explain how the calcifications evolve. The calcifications grew on average 41 % (p...... aorta wall and 21 $% (p aorta. We have made a prediction model for the atherosclerotic growth that is significantly better to predicting...

  8. The PAW/GIPAW approach for computing NMR parameters: a new dimension added to NMR study of solids.

    Science.gov (United States)

    Charpentier, Thibault

    2011-07-01

    In 2001, Mauri and Pickard introduced the gauge including projected augmented wave (GIPAW) method that enabled for the first time the calculation of all-electron NMR parameters in solids, i.e. accounting for periodic boundary conditions. The GIPAW method roots in the plane wave pseudopotential formalism of the density functional theory (DFT), and avoids the use of the cluster approximation. This method has undoubtedly revitalized the interest in quantum chemical calculations in the solid-state NMR community. It has quickly evolved and improved so that the calculation of the key components of NMR interactions, namely the shielding and electric field gradient tensors, has now become a routine for most of the common nuclei studied in NMR. Availability of reliable implementations in several software packages (CASTEP, Quantum Espresso, PARATEC) make its usage more and more increasingly popular, maybe indispensable in near future for all material NMR studies. The majority of nuclei of the periodic table have already been investigated by GIPAW, and because of its high accuracy it is quickly becoming an essential tool for interpreting and understanding experimental NMR spectra, providing reliable assignments of the observed resonances to crystallographic sites or enabling a priori prediction of NMR data. The continuous increase of computing power makes ever larger (and thus more realistic) systems amenable to first-principles analysis. In the near future perspectives, as the incorporation of dynamical effects and/or disorder are still at their early developments, these areas will certainly be the prime target.

  9. The B-Li System. Calorimetric and Theoretical Studies / Układ B-Li. Badania Kalorymetryczne I Teoretyczne

    Directory of Open Access Journals (Sweden)

    Dębski A.

    2015-12-01

    Full Text Available The standard enthalpy of formation of the B78Li22 alloy was measured with the use of the water reaction calorimetric method at 25 °C (298 K. An X-ray diffraction study of the prepared sample was conducted. The obtained diffraction pattern was different from the patterns for the B3Li and B14Li3 phases. The standard enthalpy of formation obtained for the B78Li22 alloy was -39.0 ± 0.7 kJ/mole of atoms. This value corresponds well with the formation enthalpies of the phases from the boron-lithium system. Theoretical calculations of the standard enthalpy of formation were conducted for the B78Li22 alloy and the phases from B-Li system, which were investigated earlier. A discussion of the deviations observed between both sets of data (experimental and calculated was performed. Additionally, DTA studies were performed for 14 alloys of the concentrations from 40 to 100 at. % of Li.

  10. Ad aptation of Clinical Decision Making in Nursing Scale to Undergraduate Students of Nursing: The Study of Reliability and Validity

    Directory of Open Access Journals (Sweden)

    Aylin Durmaz Edeer

    2015-09-01

    Full Text Available A clinical decision making skill is essential in the implementation of nursing knowledge and reflecting on patient care. The research was planned to measure the reliability and validity of The Clinical Decision Making in Nursing Scale (CDMNSTr for undergraduate nursing students from Turkey. This study is a methodological design. This study was conducted on 210 undergraduate students of nursing. For validity; Language – Content Validity and Construct Validity (Exploratory and Confirmatory Factor Analysis were examined. For reliability; CDMNS’s Cronbach’s alpha reliability coefficient, item-total score correlation coefficients and stability analysis (test-retest were examined. Item Content Validity Index and Scale Content Validity Index were calculated as .81 and .83 respectively. Confirmatory factor analyses showed that goodness of fit indexes were acceptable. Cronbach alpha value of the scale was .78. Item-to-total score correlation coefficients ranged from .13 to .56. The correlation coefficient for test-retest was .82. The scale can be used as a valid and reliable measurement tool to determine the perceptions of Turkish undergraduate students of nursing regarding to clinical decision making.

  11. Study on Remote Data Acquisition & Preprocessing Based on Ad hoc and Lab VIEW%基于Ad hoc和Lab VIEW的远程数据采集及预处理的研究

    Institute of Scientific and Technical Information of China (English)

    王建芳; 李伟华

    2008-01-01

    针对基于Ad hoe无线网络环境下的远程自动测试智能信息处理系统的多扰动、紧耦合的特点,提出了在Ad hoc网络环境下基于Lab VIEW 提取多传感器特征参数并进行预处理的技术,实现了实时动态的监测、数据的存储、远程通信和回放显示;采用Lab VIEW和网络传输技术,实现了远程测试系统的数据采集和预处理平台的开发;实测结果分析表明,经过数据采集及预处理后,降低了冗余数据量,提高了网络资源利用率,减少了系统开发成本.

  12. 资源受限的Ad hoc网络中节点协作激励机制研究%Study on nodes cooperation incentive mechanism for Ad hoc network with resources constraint

    Institute of Scientific and Technical Information of China (English)

    李瑾; 刘玉清; 袁红

    2014-01-01

    Aiming at the selfishness of nodes in mobile Ad hoc network , a node status based incentive mechanism ( NSIM ) is proposed in this paper . Virtual money is used to motivate the nodes forwarding data . The node designs prices taking into account the nodes′ status to avoid nodes with limited resources participating in forwarding data . A safety module encryption mechanism is imported into the mechanism to prevent some nodes from tampering other nodes′ quoted price and illegitimately increasing its own virtual money . Simulation results show that NSIM mechanism can decrease the delivery delay and increase the delivery ratio .%针对移动 Ad hoc 网络中节点自私性问题,提出了一种基于节点状态的节点协作激励机制NSIM。利用虚拟货币来激励中间节点转发数据,节点的报价是综合考虑节点状态计算得出的,避免资源紧张的节点参与数据转发;在节点中引入安全模块和加密机制,防止节点篡改其他节点的报价和非法增加虚拟货币。仿真实验表明, NSIM 机制减小了时延,提高了分组投递率。

  13. HELIAS stellarator reactor studies and related European technology studies

    Energy Technology Data Exchange (ETDEWEB)

    Grieger, G. (Max-Planck-Institut fuer Plasmaphysik, EURATOM-Association, D-85748 Garching (Germany)); Nuehrenberg, J. (Max-Planck-Institut fuer Plasmaphysik, EURATOM-Association, D-85748 Garching (Germany)); Renner, H. (Max-Planck-Institut fuer Plasmaphysik, EURATOM-Association, D-85748 Garching (Germany)); Sapper, J. (Max-Planck-Institut fuer Plasmaphysik, EURATOM-Association, D-85748 Garching (Germany)); Wobig, H. (Max-Planck-Institut fuer Plasmaphysik, EURATOM-Association, D-85748 Garching (Germany))

    1994-08-01

    Research on stellarators has been carried out in Europe since the early years of the fusion programme. Early studies of this reactor concept were done at the Culham Laboratory of the UK Atomic Energy Authority. Such classical stellarators, however, have poor reactor prospects in spite of the significant advantage of not needing a large toroidal plasma current. It seemed to be just this large toroidal plasma current which has led to intrinsic deficiencies with respect to reactor potential of the tokamak. Expecting that these deficiencies would disappear for a concept without such a current, the Institut fuer Plasmaphysik developed, in a roll-back fashion, i.e. by starting from reactor considerations, the concept of the helical axis advanced stellarator (HELIAS). The results achieved look very promising indeed. Since tokamaks and stellarators show many similarities, there appeared no need as yet for a new stand-alone stellarator reactor study. The work was rather concentrated on the few but decisive differences between the two concepts and on evaluation of their relative importance. Studies on the coil system, the stress distribution in the supporting material, the space needed for an efficient blanket system, the properties of the exhaust system, etc. have been done. Applying contemporary scaling laws, it turns out that although the aspect ratio of such advanced stellarators is larger than that of tokamaks, the plasma volume is about the same. The magnetic energy needed for plasma confinement is considerably lower and the mass utilization tends to be larger than for comparable tokamaks. It also follows that a number of reactor components needed for tokamak operation (e.g. current drive, feedback stabilization, disruption prevention) are not needed in stellarators, making this type of reactor and its operation simpler. Such results would have a large influence on selection of the final concept and the further evolution of the fusion programme.

  14. Quantum cat map dynamics on AdS$_2$

    CERN Document Server

    Axenides, Minos; Nicolis, Stam

    2016-01-01

    We present a toy model for the chaotic unitary scattering of single particle wave packets on the radial AdS$_2$ geometry of extremal BH horizons. Based on our recent work for the discretization of the AdS$_2$ space-time, which describes a finite and random geometry, by modular arithmetic, we investigate the validity of the eigenstate thermalization hypothesis (ETH), as well as that of the fast scrambling time bound conjecture (STB), for an observer with time evolution operator the quantum Arnol'd cat map (QACM). We find that the QACM, while possessing a linear spectrum, has eigenstates, which can be expressed in closed form, are found to be random and to satisfy the assumptions of the ETH.The implications are that the dynamics is described by a chaotic, unitary, single particle S-matrix, which completely delocalizes and randomizes initial gaussian wave packets . Applying results obtained by Dyson and Falk for the periods of the Arnol'd Cat Map(ACM),which are related to its mixing time, we also find that the t...

  15. Study of spallation target of ADS neutron source based on MCNPX%基于MCNPX对ADS中子源散裂靶的物理研究

    Institute of Scientific and Technical Information of China (English)

    时磊; 景桂芬

    2011-01-01

    The spallation target of Accelerator-Driven sub-critical System (ADS) is studied using the program MCNPX. The calculation of standard lead target bombarded with 0. 6 - 1. 5 GeV proton beams is carried out. The neutron spectra and distribution over the lead target,energy deposition and neutron production in the lead target are studied. The simulation results agree with the former theoretical and experimental results.%运用蒙卡程序MCNPX对加速器驱动次临界反应堆系统(简称ADS)的标准散裂中子靶进行了计算研究.计算了在0.6~1.5 GeV的质子轰击下,标准Pb靶发生散裂反应产生的中子产额及分布、中子能谱以及靶内能量沉积分布.计算结果与文献理论数据、实验数据进行了比较.

  16. Value adding management: A concept and a case

    DEFF Research Database (Denmark)

    2012-01-01

    Purpose: To develop a management concept that can assist facilities managers in implementing value adding strategies and practices. The FM Value Map has been developed to analyse and demonstrate the different ways FM can add value. However, there is a need to develop management tools that can...... be used more directly and proactively by facilities managers to implement adding value strategies and practices. Methodology: The development of the concept of Value Adding Management is based on the management model for FM included in the European FM standards, recent theories on added value of FM...... and real estate and the related concept of Value Management from building projects. The chapter outlines a preliminary theoretical based management concept, which is investigated, tested and discussed based on a case study of LEGO. Findings: The case study provides a clear example of a company that actual...

  17. Food branding influences ad libitum intake differently in children depending on weight status. Results of a pilot study.

    Science.gov (United States)

    Forman, Jamie; Halford, Jason C G; Summe, Heather; MacDougall, Megan; Keller, Kathleen L

    2009-08-01

    Environmental changes have facilitated the rapid increase in childhood obesity. One such change is increased presence of food marketing which promotes intake of high-fat, energy-dense foods. This study tested the hypotheses that overweight (OW) children are more sensitive to the intake-enhancing effects of food branding than non-OW children, and that the relationship between weight status and intake of branded foods is mediated by level of food brand awareness. Forty-three non-OW (n = 23) and OW (n = 20) children from diverse ethnic backgrounds participated in four dinnertime visits to test their intake of meals where food brands were present ("branded") or absent ("unbranded"). Food brand awareness was assessed by testing children's abilities to match food brand logos with correct foods and name specific brands from recall. Weight and height were measured on the first visit to determine BMI z-score and weight status. OW children consumed significantly more energy per meal than non-OW. Child age and brand awareness were positively associated. OW children consumed an additional 40 kcal in branded vs. unbranded meals whereas non-OW children consumed 45 kcal less in branded meals. Overweight children showed greater responsiveness to food branding, and they may be at risk in environments that are highly inundated with messages about food.

  18. A Study of Process Dissociation of the Memory Effects of Sexual Appeal Printed AD%平面性诉求广告记忆效果的加工分离研究

    Institute of Scientific and Technical Information of China (English)

    彭彦琴

    2011-01-01

    With the increasingly fierce market competition,marketeers resort all the more to sexual appeal AD to attract consumers,increase consumer interest,and improve the advertisement effect.Therefore,an appropriate degree of sexual appeal and an analysis of advertisement audience cognitive information processing by sexual appeal are important.With the proliferation of advertising messages,advertisers are increasingly using sex appeal to attract the audiences attention.Despite a number of relevant studies at home and abroad, no agreement has been reached in terms of sexual appeal AD or the celebrity effect. Past studies used two methods to study the effects of advertising memory:direct measurement(e.g.recall,recognition) and implicit attitude.In fact,neither of the methods can distinguish between explicit and implicit memory.In the research of sexual appeal AD,most of the experimental results are from America,and local experiments are relatively few.So we need a new method and perspective for the study.In order to improve the memory effect of sexual appeal AD,analyzing the audience information processing sexual appeal AD is particularly important.Thus,this research used the PDP method to distinguish between the implicit and explicit information processing of audience to sexual appeal AD,to explore the information processing model and to explore the causes.In the study, 122 college students were chosen as testees.The study involved a 3×2×2 factorial experiment to investigate how cognitive information processing would respond to sexual appeal AD by analyzing the response to the bare type(implicative,generally,explicit) and different types of celebrity spokespersons(famous,ordinary ) in advertising. The results showed that 1.From the explicit control of processing,memory of implicative sexual appeal AD got the best effect.2. From the implicit automation processing,the automatic processing of explicit sexual appeal AD got the best effect.People paid more

  19. Online Ad Slotting With Cancellations

    CERN Document Server

    Constantin, Florin; Muthukrishnan, S; Pal, Martin

    2008-01-01

    Many advertisers buy advertisements (ads) on the Internet or on traditional media and seek simple, online mechanisms to reserve ad slots in advance. Media publishers represent a vast and varying inventory, and they too seek automatic, online mechanisms for pricing and allocating such reservations. In this paper, we present and study a simple model for auctioning such ad slots in advance. Bidders arrive sequentially and report which slots they are interested in. The seller must decide immediately whether or not to grant a reservation. Our model allows a seller to accept reservations, but possibly cancel the allocations later and pay the bidder a cancellation compensation (bump payment). Our main result is an online mechanism to derive prices and bump payments that is efficient to implement. This mechanism has many desirable properties. It is individually rational; winners have an incentive to be honest and bidding one's true value dominates any lower bid. Our mechanism's efficiency is within a constant fractio...

  20. On circular strings in (AdS3 × S 3)ϰ

    Science.gov (United States)

    Banerjee, Aritra; Panigrahi, Kamal L.

    2016-09-01

    The so called one-parameter (often called ϰ) deformed AdS string sigma models have attracted a lot of attention lately in the study of integrability in string theory. We construct various circular string solutions in the (AdS3 × S 3) ϰ background and describe the characteristics of such solutions qualitatively. We study the Bohr-Sommerfeld like quantization for these string states to characterise the motion. Further we find a `long' string limit of such circular strings in the ϰ-deformed AdS3 and find a novel dependence of the oscillation number on the energy in the next to leading order expansion.

  1. On circular strings in $(AdS_3 \\times S^3)_{\\varkappa}$

    CERN Document Server

    Banerjee, Aritra

    2016-01-01

    The so called one-parameter (often called $\\varkappa$) deformed $AdS$ string sigma models have attracted a lot of attention lately in the study of integrability in string theory. We construct various circular string solutions in the $(AdS_3 \\times S^3)_{\\varkappa}$ background and describe the characteristics of such solutions qualitatively. We study the Bohr-Sommerfeld like quantization for these string states to characterise the motion. Further we find a `long' string limit of such circular strings in the $\\varkappa$-deformed $AdS_3$ and find a novel dependence of the oscillation number on the energy in the next to leading order expansion.

  2. Results from Ad Hoc and Routinely Collected Data among Celiac Women with Infertility or Pregnancy Related Disorders: Italy, 2001–2011

    Directory of Open Access Journals (Sweden)

    Francesca Fortunato

    2014-01-01

    Full Text Available Celiac disease (CD is a chronic autoimmune illness triggered by gluten consumption in genetically predisposed individuals. Worldwide, CD prevalence is approximately 1%. Several studies suggest a higher prevalence of undiagnosed CD in patients with infertility. We described reproductive disorders and assessed the frequency of hospital admissions for infertility among celiac women aged 15–49. We conducted two surveys enrolling a convenient sample of celiac women, residing in Apulia or in Basilicata (Italy. Moreover, we selected hospital discharge records (HDRs of celiac women and women with an exemption for CD, and matched the lists with HDRs for reproductive disorders. In the surveys we included 91 celiac women; 61.5% of them reported menstrual cycle disorders. 47/91 reported at least one pregnancy and 70.2% of them reported problems during pregnancy. From the HDRs and the registry of exemption, we selected 4,070 women with CD; the proportion of women hospitalized for infertility was higher among celiac women than among resident women in childbearing age (1.2% versus 0.2%. Our findings highlight a higher prevalence of reproductive disorders among celiac women than in the general population suggesting that clinicians might consider testing for CD women presenting with pregnancy disorders or infertility.

  3. Added value of contrast-enhanced CISS imaging in relation to conventional MR images for the evaluation of intracavernous cranial nerve lesions

    Energy Technology Data Exchange (ETDEWEB)

    Yagi, Akiko; Takahashi, Ayako; Morita, Hideo; Amanuma, Makoto; Endo, Keigo [Gunma University School of Medicine, Department of Diagnostic Radiology and Nuclear Medicine, Gunma (Japan); Sato, Noriko [National Center Hospital of Neurology and Psychiatry, Department of Radiology, Kodaira, Tokyo (Japan); Takeuchi, K. [Takasaki University of Health and Welfare, Department of Health and Welfare, Gunma (Japan)

    2010-12-15

    The normal cranial nerves (CNs) of the cavernous sinus can be clearly demonstrated using contrast-enhanced constructive interference in steady-state (CISS) magnetic resonance imaging (MRI). This study used the method to evaluate pathological CNs III, IV, V{sub 1}, V{sub 2}, and VI in cavernous sinuses affected by inflammatory and neoplastic diseases. MR images from 17 patients with diseases involving the cavernous sinuses and/or causing neuropathy in CNs III-VI were retrospectively evaluated. The patients were divided into inflammatory (n = 11) and neoplastic (n = 6) groups. We defined CNs as abnormal when they exhibited enlargement or enhancement. CNs were evaluated using both contrast-enhanced CISS and T1-weighted MRI. In the inflammatory group, abnormal CNs were identified by contrast-enhanced CISS MRI in 13 of 25 symptomatic CNs (52%) in eight patients, but in only two CNs (8%) in two patients by contrast-enhanced T1-weighted MRI. In the neoplastic group, both sequences of contrast-enhanced CISS and T1-weighted MRI detected abnormalities in the same three of eight symptomatic CNs (37.5%), i.e., the three CNs were all in the same patient with adenoid cystic carcinoma. Contrast-enhanced CISS MRI is useful for detecting CN abnormalities in inflammatory pathological conditions of the cavernous sinuses. (orig.)

  4. CFT correlation functions from AdS/CFT correspondence

    Science.gov (United States)

    Matusis, Alec

    In this thesis we discuss correlation functions of N = 4, d = 4 Super-Yang-Mills theory in the strong coupling regime. Namely, the recent conjecture of the equivalence of the string theory in AdS5 x S5 background to the N = 4, d = 4 SYM theory with SU( N) gauge group allows to find correlation functions of the CFT in the limit of large t'Hooft coupling and at large N by evaluating relatively simple tree-level supergravity amplitudes. We discuss the basic ideas of the AdS supergravity computations, and establish the techniques for evaluating tree-level AdS supergravity scattering amplitudes with fixed rates of fall-offs of the fields as they approach AdS boundary. We translate these supergravity results into field theory language and learn several interesting things. First, at the level of the two-point correlation functions we learn about the necessity for the introduction of a cut-off in seemingly convergent AdS supergravity computations. Next, we find a non-renormalization property of certain 3-point functions. Finally, we find an explicit expression for certain 4-point functions, which deviate from free-field approximation in perturbation theory, thus providing some new non- perturbative information about SYM. We study various limits of these 4-point functions, with intention to give them an OPE interpretation. We find logarithmic singularities in all limits, and discuss their compatibility with existence of an OPE at strong coupling. (Copies available exclusively from MIT Libraries, Rm. 14-0551, Cambridge, MA 02139-4307. Ph. 617-253-5668; Fax 617-253-1690.)

  5. THE DISCUSSION OF NOUN COMPLEMENTS WITH NO SUFFIXES AND THE RELATION BETWEEN WORD CLASSES AND PHRASES TAKISIZ AD TAMLAMASI TARTIŞMASI VE TÜR – ÖBEK İLİŞKİSİ

    Directory of Open Access Journals (Sweden)

    Caner KERİMOĞLU

    2011-01-01

    Full Text Available The discussion of compound nouns with no suffixes has an important place in Turkish grammar writing. Recently, it is seen that this discussion has come to an end and the constructions like tahta kaşık “wooden spoon”, altın kolye “golden necklace” are accepted as adjective complements. In this study, firstly these discussions are evaluated and then the roles of word classes in phrases are discussed with regard to nouns and adjectives. Takısız ad tamlaması tartışması Türkçe dil bilgisi yazımında önemli bir yere sahiptir. Son yıllarda bu konuyla ilgili tartışmaların azaldığı ve akademik yayınların çoğunda tahta kaşık, altın kolye dizilişindeki yapıların sıfat tamlaması kabul edildiği görülmektedir. Bu çalışmada takısız ad tamlaması tartışmaları değerlendirildikten sonra, kelime türlerinin öbek kurmadaki rolleri sıfat ve ad türleri temelinde tartışılmaktadır.

  6. How physics teachers approach innovation: An empirical study for reconstructing the appropriation path in the case of special relativity

    OpenAIRE

    Anna De Ambrosis; Olivia Levrini

    2010-01-01

    This paper concerns an empirical study carried out with a group of high school physics teachers engaged in the Module on relativity of a Master course on the teaching of modern physics. The study is framed within the general research issue of how to promote innovation in school via teachers’ education and how to foster fruitful interactions between research and school practice via the construction of networks of researchers and teachers. In the paper, the problems related to innovation are ad...

  7. AdS nonlinear instability: moving beyond spherical symmetry

    Science.gov (United States)

    Dias, Óscar J. C.; Santos, Jorge E.

    2016-12-01

    Anti-de Sitter (AdS) is conjectured to be nonlinear unstable to a weakly turbulent mechanism that develops a cascade towards high frequencies, leading to black hole formation (Dafermos and Holzegel 2006 Seminar at DAMTP (University of Cambridge) available at https://dpmms.cam.ac.uk/~md384/ADSinstability.pdf, Bizon and Rostworowski 2011 Phys. Rev. Lett. 107 031102). We give evidence that the gravitational sector of perturbations behaves differently from the scalar one studied by Bizon and Rostworowski. In contrast with Bizon and Rostworowski, we find that not all gravitational normal modes of AdS can be nonlinearly extended into periodic horizonless smooth solutions of the Einstein equation. In particular, we show that even seeds with a single normal mode can develop secular resonances, unlike the spherically symmetric scalar field collapse studied by Bizon and Rostworowski. Moreover, if the seed has two normal modes, more than one resonance can be generated at third order, unlike the spherical collapse of Bizon and Rostworowski. We also show that weak turbulent perturbative theory predicts the existence of direct and inverse cascades, with the former dominating the latter for equal energy two-mode seeds.

  8. The electrooxidation mechanism of formic acid on platinum and on lead ad-atoms modified platinum studied with the kinetic isotope effect

    Science.gov (United States)

    Bełtowska-Brzezinska, M.; Łuczak, T.; Stelmach, J.; Holze, R.

    2014-04-01

    Kinetics and mechanism of formic acid (FA) oxidation on platinum and upd-lead ad-atoms modified platinum electrodes have been studied using unlabelled and deuterated compounds. Poisoning of the electrode surface by CO-like species was prevented by suppression of dissociative chemisorption of FA due to a fast competitive underpotential deposition of lead ad-atoms on the Pt surface from an acidic solution containing Pb2+ cations. Modification of the Pt electrode with upd lead induced a catalytic effect in the direct electrooxidation of physisorbed FA to CO2. With increasing degree of H/D substitution, the rate of this reaction decreased in the order: HCOOH > DCOOH ≥ HCOOD > DCOOD. HCOOH was oxidized 8.5-times faster on a Pt/Pb electrode than DCOOD. This primary kinetic isotope effect proves that the C-H- and O-H-bonds are simultaneously cleaved in the rate determining step. A secondary kinetic isotope effect was found in the dissociative chemisorption of FA in the hydrogen adsorption-desorption range on a bare Pt electrode after H/D exchange in the C-H bond, wherein the influence of deuterium substitution in the O-H group was negligibly small. Thus the C-H bond cleavage is accompanied by the C-OH and not the O-H bond split in the FA decomposition, producing CO-like species on the Pt surface sites.

  9. Sensitivity and Specificity of the Screen for Child Anxiety Related Emotional Disorders (SCARED): A Community-Based Study

    Science.gov (United States)

    DeSousa, Diogo Araujo; Salum, Giovanni Abrahao; Isolan, Luciano Rassier; Manfro, Gisele Gus

    2013-01-01

    The aim of this cross-sectional community-based study was to examine the sensitivity and specificity of the Screen for Child Anxiety Related Emotional Disorders (SCARED) to the diagnosis of anxiety disorders (AD). Participants were 119 students aged 9-18. Psychiatric diagnoses were assessed by a psychiatrist throughout a structural clinical…

  10. The effect of adding core stability training to a standard balance exercise program on sit to stand performance in older adults: a pilot study.

    Science.gov (United States)

    Arnold, Cathy; Lanovaz, Joel; Oates, Alison; Craven, Bruce; Butcher, Scotty

    2015-01-01

    This study compared sit to stand (STS) performance between older adults in a nine-week training program focusing on core stability exercises to enhance balance and postural control (EB) versus standard balance (SB) exercises. Repetitions in 30 s (STSreps) and kinematic performance (vertical and horizontal momentum, and margin of stability) were measured pre and postintervention in 23 older adults with at least one fall risk factor. Although both groups combined improved STSreps (P = .001) and vertical momentum (.008), a significant between-group difference was observed for completers only (MANCOVA of posttest group differences, with pretest scores as covariates; P = .04). EB demonstrated a greater but nonsignificant improvement in vertical momentum (P = .095). In conclusion, core stability training added to SB did not result in STS reps improvement. Compliance may modify these results and future larger sample studies should evaluate the impact of core stability training on STS biomechanics.

  11. Carbon-Supported Fe Catalysts for CO2 Electroreduction to High-Added Value Products: A DEMS Study: Effect of the Functionalization of the Support

    Directory of Open Access Journals (Sweden)

    S. Pérez-Rodríguez

    2011-01-01

    Full Text Available Vulcan XC-72R-supported Fe catalysts have been synthesised for the electroreduction of CO2 to high-added value products. Catalysts were obtained by the polyol method, using ethylene glycol as solvent and reducing agent. Prior to the metal deposition, Vulcan was subjected to different oxidation treatments in order to modify its surface chemistry and study its influence on the physicochemical and electrochemical properties of the catalysts, as well as on the product distribution. The oxidation treatments of the supports modify their textural properties, but do not affect significantly the physicochemical properties of catalysts. However, DEMS studies showed that the carbon support degradation, the distribution of products, and the catalytic activity toward the CO2 electroreduction reaction depend significantly on the surface chemistry of the carbon support.

  12. Eating ad Libitum

    DEFF Research Database (Denmark)

    Hillersdal, Line

    in the context of the 'ad libitum meal'. The analytical interest is thus what kind of eaters and bodies are enacted in the meal test and what ideas of prevention and treatment are embedded in their standards. Drawing from ongoing empirical work among Danish obesity researchers performing scientific meal tests I...... ask what make up food stuff and eaters in the meal tests? More specifically I explore a scientific testing of changes in taste preferences before and after weight-loss surgery using an ad libitum buffet with a selection of different foods and another testing the effect of exercise on appetite also...... using an ad libitum meal consisting of spaghetti bolognaise. I analyse the entanglement and concurrence of different knowledge practices and show how several scalings of appetite play out, one ex explaining the aim of the test, being to ”measure what your body would want the most” and hence producing...

  13. Dynamic ad hoc networks

    CERN Document Server

    Rashvand, Habib

    2013-01-01

    Motivated by the exciting new application paradigm of using amalgamated technologies of the Internet and wireless, the next generation communication networks (also called 'ubiquitous', 'complex' and 'unstructured' networking) are changing the way we develop and apply our future systems and services at home and on local, national and global scales. Whatever the interconnection - a WiMAX enabled networked mobile vehicle, MEMS or nanotechnology enabled distributed sensor systems, Vehicular Ad hoc Networking (VANET) or Mobile Ad hoc Networking (MANET) - all can be classified under new networking s

  14. Supersymmetry Properties of AdS Supergravity Backgrounds

    Science.gov (United States)

    Beck, Samuel; Gutowski, Jan; Papadopoulos, George

    2017-01-01

    Anti-de Sitter supergravity backgrounds are of particular interest in light of the AdS/CFT correspondence, which relates them to dual conformal field theories on the boundary of the anti-de Sitter space. We have investigated the forms of the supersymmetries these backgrounds preserve by solving the Killing spinor equations on the anti-de Sitter components of these spaces. We have found that a supersymmetric AdSn background necessarily preserves 2⌊n/2⌋ k supersymmetries for n 0 . Additionally, we have found that the Killing spinors of each background are exactly the zeroes of a Dirac-like operator constructed from the Killing spinor equations.

  15. A Comparative Study of Relational and Non-Relational Database Models in a Web- Based Application

    OpenAIRE

    Cornelia Gyorödi; Robert Gyorödi; Roxana Sotoc

    2015-01-01

    The purpose of this paper is to present a comparative study between relational and non-relational database models in a web-based application, by executing various operations on both relational and on non-relational databases thus highlighting the results obtained during performance comparison tests. The study was based on the implementation of a web-based application for population records. For the non-relational database, we used MongoDB and for the relational database, we used MSSQL 2014. W...

  16. Beyond the unitarity bound in AdS/CFT{sub (A)dS}

    Energy Technology Data Exchange (ETDEWEB)

    Andrade, Tomas [University of California, Santa Barbara (United States); Uhlemann, Christoph [Universitaet Wuerzburg (Germany)

    2012-07-01

    We study CFTs on dS and AdS spacetimes from a holographic perspective, in particular how the unitarity properties of the boundary theory are reflected in the bulk description. On geometries with an (A)dS conformal boundary we choose mass and boundary conditions for a Klein-Gordon field such that the corresponding CFT operator violates the unitarity bound. We analyze how the non-unitarity is reproduced in the bulk and discuss, for the case of an AdS boundary, prospects for multi-layered AdS/CFT-type dualities.

  17. Thermodynamic geometry and phase transitions of AdS braneworld black holes

    Science.gov (United States)

    Chaturvedi, Pankaj; Sengupta, Gautam

    2017-02-01

    The thermodynamics and phase transitions of charged RN-AdS and rotating Kerr-AdS black holes in a generalized Randall-Sundrum braneworld are investigated in the framework of thermodynamic geometry. A detailed analysis of the thermodynamics, stability and phase structures in the canonical and the grand canonical ensembles for these AdS braneworld black holes are described. The thermodynamic curvatures for both these AdS braneworld black holes are computed and studied as a function of the thermodynamic variables. Through this analysis we illustrate an interesting dependence of the phase structures on the braneworld parameter for these black holes.

  18. Various types of phase transitions in the AdS soliton background

    CERN Document Server

    Peng, Yan; Wang, Bin

    2011-01-01

    We study the basic holographic insulator and superconductor phase transition in the AdS soliton background by generalizing the spontaneous breaking of a global U(1) symmetry to occur via St$\\ddot{u}$ckelberg mechanism. We construct the soliton solutions with backreaction and examine the effects of the backreaction on the condensation of the scalar hair in the generalized St$\\ddot{u}$ckelberg Lagrangian. We disclose rich physics in various phase transitions. In addition to the AdS soliton configuration, we also examine the property of the phase transition in the AdS black hole background.

  19. Phase Transition and Clapeyon Equation of Black Hole in Higher Dimensional AdS Spacetime

    CERN Document Server

    Zhao, Hui-Hua; Ma, Meng-Sen; Zhao, Ren

    2014-01-01

    By Maxwell equal area law we study the phase transition in higher dimensional Anti-de Sitter (AdS) Reissner-Nordstr\\"{o}m (RN) black hole and Kerr black hole in this paper. The coexisting region of the two phases involved in the phase transition is found and the coexisting curves are shown in $P-T$ figures. We also analytically investigate the parameters which affect the coexisting curves. To better compare with ordinary thermodynamic systems, the Clapeyon equation is derived for higher dimensional AdS black holes. This paper can help to deepen the understanding of the phase transition and phase structure of AdS black holes.

  20. Political Communication: Contributions to the Study of Public Relations.

    Science.gov (United States)

    Stacks, Don W.

    Political communication has influenced greatly the study of modern public relations. The development of modern public relations can be traced back to the Ancients of Greece. The definition of "political communication" when applied to public relations is typically corporate in nature. That is, public relations defines the role of…

  1. Selling the Internet: A Cultural Studies Approach to Public Relations.

    Science.gov (United States)

    Mickey, Thomas J.

    1998-01-01

    Examines the ideology of Internet public relations. Takes a cultural studies approach to modern public relations, using public relations material as representation. Presents a case study of the MassNetworks Education Partnership, which was set up in 1996 to ensure that the Internet gets into the classroom. (PA)

  2. Content and Epistemic Relations: A Developmental Study of Recall

    Directory of Open Access Journals (Sweden)

    Sara Verbrugge

    2012-09-01

    Full Text Available The study investigates the types of coherence relations adults and children can recall after having read a text. We discerned content and epistemic relations (Dancygier, 1998; Sweetser, 1990. Content relations express relations between events in reality. Epistemic relations typically express relations between states of thinking (premise-conclusion relations. The relations between the two parts of a content or epistemic relation is often made explicit by means of connectives. The differences between these types of sentences have been shown in different areas (e.g., reasoning, clause integration, acquisition. However, no clear results could be reached as for recall of these relations and the interaction with connectives. We aim to clarify this debate by means of an experiment involving 539 participants. The experiment revealed that the difficulty associated with epistemic relations decreases as participants get older. Interestingly, connectives play a larger role in participants' ability to recall epistemic compared to content relations.

  3. Simulation Study of UHF Low Noise Amplifier Based on ADS%基于ADS的UHF低噪声放大器仿真研究

    Institute of Scientific and Technical Information of China (English)

    唐德民

    2012-01-01

    从放大器电路、放大器芯片的S参数扫描、阻抗匹配特性,分析低噪声放大器的外围器件参数设计原理,采用ADS仿真软件实例研究基于MAX2640的低噪声放大器电路设计过程,提出综合考虑增益、噪声系数和阻抗匹配的方法。%The design principle of peripheral devices parameters of low noise amplifier is analyzed based on amplifier cir- cuit and S parameter of amplifier chip and impedance matching. The design process ofMAX2640-based LNA circuit is studied using ADS simulation software. Signal gain, noise coefficient and impedance matching are considered in design.

  4. Adding liraglutide to the backbone therapy of biguanide in patients with coronary artery disease and newly diagnosed type-2 diabetes (the AddHope2 study)

    DEFF Research Database (Denmark)

    Anholm, Christian; Kumarathurai, Preman; Klit, Malene S;

    2014-01-01

    INTRODUCTION: Newly diagnosed type 2 diabetes mellitus (T2DM) in patients with coronary artery disease (CAD) more than doubles the risk of death compared with otherwise matched glucose tolerant patients. The biguanide metformin is the drug of choice in treatment of T2DM and has shown to ameliorate......), liraglutide, is currently used for treatment of T2DM but its potential effect on cardiac function has not been investigated in detail. We hypothesised that liraglutide added to metformin backbone therapy in patients with CAD and newly diagnosed T2DM will improve β-cell function and left ventricular systolic...... function during dobutamine stress. METHODS AND ANALYSES: 40 patients with CAD and newly diagnosed T2DM will receive the intervention liraglutide+metformin and placebo+metformin in this investigator-initiated, double blind, randomised, placebo-controlled, cross-over 12 plus 12 weeks intervention study...

  5. Detecting Precontact Anthropogenic Microtopographic Features in a Forested Landscape with Lidar: A Case Study from the Upper Great Lakes Region, AD 1000-1600.

    Science.gov (United States)

    Howey, Meghan C L; Sullivan, Franklin B; Tallant, Jason; Kopple, Robert Vande; Palace, Michael W

    2016-01-01

    Forested settings present challenges for understanding the full extent of past human landscape modifications. Field-based archaeological reconnaissance in forests is low-efficiency and most remote sensing techniques are of limited utility, and together, this means many past sites and features in forests are unknown. Archaeologists have increasingly used light detection and ranging (lidar), a remote sensing tool that uses pulses of light to measure reflecting surfaces at high spatial resolution, to address these limitations. Archaeology studies using lidar have made significant progress identifying permanent structures built by large-scale complex agriculturalist societies. Largely unaccounted for, however, are numerous small and more practical modifications of landscapes by smaller-scale societies. Here we show these may also be detectable with lidar by identifying remnants of food storage pits (cache pits) created by mobile hunter-gatherers in the upper Great Lakes during Late Precontact (ca. AD 1000-1600) that now only exist as subtle microtopographic features. Years of intensive field survey identified 69 cache pit groups between two inland lakes in northern Michigan, almost all of which were located within ~500 m of a lakeshore. Applying a novel series of image processing techniques and statistical analyses to a high spatial resolution DTM we created from commercial-grade lidar, our detection routine identified 139 high potential cache pit clusters. These included most of the previously known clusters as well as several unknown clusters located >1500 m from either lakeshore, much further from lakeshores than all previously identified cultural sites. Food storage is understood to have emerged regionally as a risk-buffering strategy after AD 1000 but our results indicate the current record of hunter-gatherer cache pit food storage is markedly incomplete and this practice and its associated impact on the landscape may be greater than anticipated. Our study also

  6. Added fructose: a principal driver of type 2 diabetes mellitus and its consequences.

    Science.gov (United States)

    DiNicolantonio, James J; O'Keefe, James H; Lucan, Sean C

    2015-03-01

    Data from animal experiments and human studies implicate added sugars (eg, sucrose and high-fructose corn syrup) in the development of diabetes mellitus and related metabolic derangements that raise cardiovascular (CV) risk. Added fructose in particular (eg, as a constituent of added sucrose or as the main component of high-fructose sweeteners) may pose the greatest problem for incident diabetes, diabetes-related metabolic abnormalities, and CV risk. Conversely, whole foods that contain fructose (eg, fruits and vegetables) pose no problem for health and are likely protective against diabetes and adverse CV outcomes. Several dietary guidelines appropriately recommend consuming whole foods over foods with added sugars, but some (eg, recommendations from the American Diabetes Association) do not recommend restricting fructose-containing added sugars to any specific level. Other guidelines (such as from the Institute of Medicine) allow up to 25% of calories as fructose-containing added sugars. Intake of added fructose at such high levels would undoubtedly worsen rates of diabetes and its complications. There is no need for added fructose or any added sugars in the diet; reducing intake to 5% of total calories (the level now suggested by the World Health Organization) has been shown to improve glucose tolerance in humans and decrease the prevalence of diabetes and the metabolic derangements that often precede and accompany it. Reducing the intake of added sugars could translate to reduced diabetes-related morbidity and premature mortality for populations.

  7. The Tetrahedron Zamolodchikov Algebra and the AdS5 x S5 S-matrix

    CERN Document Server

    Mitev, Vladimir; Tsuboi, Zengo

    2012-01-01

    The S-matrix of the AdS5 x S5 string theory is a tensor product of two centrally extended su(2|2) S-matrices, each of which is related to the R-matrix of the Hubbard model. The R-matrix of the Hubbard model was first found by Shastry, who ingeniously exploited the fact that, for zero coupling, the Hubbard model can be decomposed into two XX models. In this article, we review and clarify this construction from the AdS/CFT perspective and investigate the implications this has for the AdS5 x S5 S-matrix.

  8. Holographic properties in three-dimensional AdS soliton using $AdS_3/CFT_2$

    CERN Document Server

    Peng, Yan

    2016-01-01

    We study the holographic description of a superconductor by the $AdS_{3}/CFT_{2}$ correspondence. The system is constructed with a Maxwell field and a charged scalar field coupled in the (2+1)-dimensional AdS soliton background. With analytical methods, we obtain the exact expression for the critical chemical potential as $\\mu_{c} = 1 + \\sqrt{1+m^2}$, which has also been generalized to higher dimensions as $\\mu_c \\thickapprox a + \\sqrt{m^2-m_{BF}^2}$ in this work. Around the phase transition points, we find a correspondence between the value of the scalar field at the tip and the scalar operator at infinity. We also arrive at the classical second order phase transition threshold exponent $\\beta=\\frac{1}{2}$ as the same as the mean field theory near the critical chemical potential. As the condensation becomes heavier, we show surprisingly that superconducting phases exist only in a certain range of the chemical potential, which is very different from higher-dimensional cases. And for the small enough negative ...

  9. Stress-induced comenditic trachyte effusion triggered by trachybasalt intrusion: multidisciplinary study of the AD 1761 eruption at Terceira Island (Azores)

    Science.gov (United States)

    Pimentel, A.; Zanon, V.; de Groot, L. V.; Hipólito, A.; Di Chiara, A.; Self, S.

    2016-03-01

    The AD 1761 eruption on Terceira was the only historical subaerial event on the island and one of the last recorded in the Azores. The eruption occurred along the fissure zone that crosses the island and produced a trachybasalt lava flow and scoria cones. Small comenditic trachyte lava domes (known as Mistérios Negros) were also thought by some to have formed simultaneously on the eastern flank of Santa Bárbara Volcano. Following a multidisciplinary approach, we combined geological mapping, paleomagnetic, petrographic, mineral and whole-rock geochemical and structural analyses to study this eruption. The paleomagnetic dating method compared geomagnetic vectors (directions and intensities) recorded by both the AD 1761 lava flow and Mistérios Negros domes and revealed that the two events were indeed coeval. Based on new data and interpretation of historical records, we have accordingly reconstructed the AD 1761 eruptive dynamics and distinguished three phases: (1) a precursory phase characterized by decreased degassing in the fumarolic field of Pico Alto Volcano and a gradual increase of seismic activity, which marked the intrusion of trachybasalt magma; (2) a first eruptive phase that started with phreatic explosions on the eastern flank of Santa Bárbara Volcano, followed by the inconspicuous effusion of comenditic trachyte (66 wt% SiO2), forming a WNW-ESE-oriented chain of lava domes; and (3) a second eruptive phase on the central part of the fissure zone, where a Hawaiian to Strombolian-style eruption formed small scoria cones (E-W to ENE-WSW-oriented) and a trachybasalt lava flow (50 wt% SiO2) which buried 27 houses in Biscoitos village. Petrological analyses show that the two batches of magma were emitted independently without evidence of interaction. We envisage that the dome-forming event was triggered by local stress changes induced by intrusion of the trachybasalt dyke along the fissure zone, which created tensile stress conditions that promoted ascent

  10. A Comparative Study of Relational and Non-Relational Database Models in a Web- Based Application

    Directory of Open Access Journals (Sweden)

    Cornelia Gyorödi

    2015-11-01

    Full Text Available The purpose of this paper is to present a comparative study between relational and non-relational database models in a web-based application, by executing various operations on both relational and on non-relational databases thus highlighting the results obtained during performance comparison tests. The study was based on the implementation of a web-based application for population records. For the non-relational database, we used MongoDB and for the relational database, we used MSSQL 2014. We will also present the advantages of using a non-relational database compared to a relational database integrated in a web-based application, which needs to manipulate a big amount of data.

  11. Automated chemoenzymatic synthesis of no-carrier-added [carbonyl-{sup 11}C]propionyl L-carnitine for pharmacokinetic studies

    Energy Technology Data Exchange (ETDEWEB)

    Davenport, R.J.; Pike, V.W.; Dowsett, K.; Turton, D.R.; Poole, K. [Hammersmith Hospital, London (United Kingdom). MRC Cyclotron Unit

    1997-07-30

    Propionyl-L-carnitine (PLC) is under development as a therapeutic for the treatment of peripheral artery disease, coronary heart disease and chronic heart failure. Three methods were examined for labelling PLC in its propionyl group with positron-emitting carbon-11 (t{sub 1/2} = 20.3 min), one chemical and two chemoenzymatic. The former was based on the preparation of [{sup 11}C]propionyl chloride as labelling agent via {sup 11}C-carboxylation of ethylmagnesium bromide with cyclotron-produced [{sup 11}C]carbon dioxide and subsequent chlorination. Reaction of carrier-added [{sup 11}C]propionyl chloride with L-carnitine in trifluoroacetic acid gave [{sup 11}C]PLC in 12% radiochemical yield (decay-corrected) from cyclotron-produced [{sup 11}C]carbon dioxide. However, the radiosynthesis was unsuccessful at the no-carrier added (NCA) level of specific radioactivity. [{sup 11}C]Propionate, as a radioactive precursor for chemoenzymatic routes, was prepared via carboxylation of ethylmagnesium bromide with [{sup 11}C]carbon dioxide and hydrolysis. NCA [{sup 11}C]PLC was prepared in 68 min in 14% radiochemical yield (decay-corrected) from [{sup 11}C]propionate via sequential conversions catalysed by acetate kinase, phosphotransacetylase and carnitine acetyltransferase. A superior chemoenzymatic synthesis of NCA [{sup 11}C]PLC was developed, based on the use of a novel supported Grignard reagent for the synthesis of [{sup 11}C]propionate and conversions by S-acetyl-CoA synthetase and carnitine acetyltransferase. This gave an overall radiochemical yield of 30-48% (decay-corrected). This synthesis was automated for radiation safety and provides pure NCA [{sup 11}C]PLC in high radioactivities ready for intravenous administration within 25 min from radionuclide production. The [{sup 11}C]PLC is suitable for pharmacokinetic studies in human subjects with PET and the elucidation of the fate of the propionyl group of PLC in vivo. (Author).

  12. The summary of researches on ADS in China

    Institute of Scientific and Technical Information of China (English)

    XIA Haihong; CUI Baoqun; ZHAO Zhixiang; LI Jigen; SHI Yongqian; HAN Yinlu; ZHU Shengyun; XU Yongli; GUAN Xialing; FU Shinian

    2007-01-01

    The conceptual study on the accelerator driven system (ADS) that lasted for about five years ended in 1999 in China. As one project of the National Basic Research Program of China (973 Program) in the energy domain, which is sponsored by the China Ministry of Science and Technology (MOST), a five-year-program of fundamental research of ADS physics and related technology was launched in 2000 and passed national review at the end of 2005. The China Institute of Atomic Energy (CIAE), the Institute of High Energy Physics (IHEP), the Institute of Heavy Ion Physics in Peking University (PKU-IHIP) and other institutions jointly carried out the research. The research activities were focused on HPPA physics and technology, reactor physics of external source driven sub-critical assembly, nuclear data base and material study. For HPPA, a high current injector consisting of an ECR ion source, LEBT and an RFQ accelerating structure of 3.5 MeV was built. In reactor physics study, a series of neutron multiplication experimental study has been carded out and still being done. The VENUS facility has been constructed as the basic experimental platform for neutronics study in ADS blanket. It's a zero power sub-critical neutron multiplying assembly driven by external neutron produced by a pulsed neutron generator. The theoretical, experimental and simulation study on nuclear data, matcrial properties and nuclear fuel circulation related to ADS is carrying on to provide the database for ADS system analysis. The main results on ADS related researches will be reported.

  13. Null-polygonal minimal surfaces in AdS_4 from perturbed W minimal models

    CERN Document Server

    Hatsuda, Yasuyuki; Satoh, Yuji

    2012-01-01

    We study the null-polygonal minimal surfaces in AdS_4, which correspond to the gluon scattering amplitudes/Wilson loops in N=4 super Yang-Mills theory at strong coupling. The area of the minimal surfaces with n cusps is characterized by the thermodynamic Bethe ansatz (TBA) integral equations or the Y-system of the homogeneous sine-Gordon model, which is regarded as the SU(n-4)_4/U(1)^{n-5} generalized parafermion theory perturbed by the weight-zero adjoint operators. Based on the relation to the TBA systems of the perturbed W minimal models, we solve the TBA equations by using the conformal perturbation theory, and obtain the analytic expansion of the remainder function around the UV/regular-polygonal limit for n=6 and 7. We compare the rescaled remainder function for n=6 with the two-loop one, to observe that they are close to each other similarly to the AdS_3 case.

  14. Teacher Leader Human Relations Skills: A Comparative Study

    Science.gov (United States)

    Roby, Douglas E.

    2012-01-01

    In this study, 142 graduate school teachers working in schools throughout southwestern Ohio assessed their human relation skills. A human relations survey was used for the study, and results were compared with colleagues assessing the teachers in the study. The survey was developed using a Likert-type scale, and was based on key elements affecting…

  15. Adding linear orders

    CERN Document Server

    Shelah, Saharon

    2011-01-01

    We address the following question: Can we expand an NIP theory by adding a linear order such that the expansion is still NIP? Easily, if acl(A)=A for all A, then this is true. Otherwise, we give counterexamples. More precisely, there is a totally categorical theory for which every expansion by a linear order has IP. There is also an \\omega-stable NDOP theory for which every expansion by a linear order interprets bounded arithmetic.

  16. An Investigation of AdS2 Backreaction and Holography

    CERN Document Server

    Engelsöy, Julius; Verlinde, Herman

    2016-01-01

    We investigate a dilaton gravity model in AdS2 proposed by Almheiri and Polchinski and develop an 1D effective description in terms of a dynamical boundary time with a Schwarzian derivative action. We show that the effective model is equivalent to a 1D version of Liouville theory, and investigate its dynamics and symmetries via a standard canonical framework. We include the coupling to arbitrary conformal matter and analyze the effective action in the presence of possible sources. We compute commutators of local operators at large time separation, and match the result with the time shift due to a gravitational shockwave interaction. We study a black hole evaporation process and comment on the role of entropy in this model.

  17. On Information Loss in AdS$_3$/CFT$_2$

    CERN Document Server

    Fitzpatrick, A Liam; Li, Daliang; Wang, Junpu

    2016-01-01

    We discuss information loss from black hole physics in AdS$_3$, focusing on two sharp signatures infecting CFT$_2$ correlators at large central charge $c$: 'forbidden singularities' arising from Euclidean-time periodicity due to the effective Hawking temperature, and late-time exponential decay in the Lorentzian region. We study an infinite class of examples where forbidden singularities can be resolved by non-perturbative effects at finite $c$, and we show that the resolution has certain universal features that also apply in the general case. Analytically continuing to the Lorentzian regime, we find that the non-perturbative effects that resolve forbidden singularities qualitatively change the behavior of correlators at times $t \\sim S_{BH}$, the black hole entropy. This may resolve the exponential decay of correlators at late times in black hole backgrounds. By Borel resumming the $1/c$ expansion of exact examples, we explicitly identify 'information-restoring' effects from heavy states that should correspo...

  18. AdS 3-manifolds and Higgs bundles

    DEFF Research Database (Denmark)

    Alessandrini, Daniele; Li, Qiongling

    2015-01-01

    In this paper we investigate the relationships between closed AdS 3-manifolds and Higgs bundles. We have a new way to construct AdS structures that allows us to see many of their properties explicitly, for example we can recover the very recent formula by Tholozan for the volumes. We also find...

  19. Clinical study on IgG4-related autoimmune pancreatitis

    Institute of Scientific and Technical Information of China (English)

    吴庆军

    2013-01-01

    Objective To investigate the clinical features of IgG4-related autoimmune pancreatitis(IgG4-related AIP). Methods A prospective cohort study on IgG4 related disease(IgG4-RD) was carried out in Peking Union Medical College Hospital during December 2010 to June

  20. Gauge Symmetries and Holographic Anomalies of Chern-Simons and Transgression AdS Gravity

    CERN Document Server

    Mora, Pablo

    2014-01-01

    We review the issue of gauge and gravitational anomalies with backgrounds, maybe offering a new outlook on some aspects of these questions. We compute the holographic anomalies of hypothetical theories dual, in the sense of the AdS-CFT correspondence, to Chern-Simons AdS gravities. Those anomalies are either gauge anomalies associated to the AdS gauge group of the theory or diffeomorphism anomalies, with each kind related to the other. As a result of using suitable action principles por Chern-Simons AdS gravities, coming from Transgression forms, we obtain finite results without the need for further regularization. Our results are of potential interest for Lovelock gravity theories, as it has been shown that the boundary terms dictated by the transgressions for Chern-Simons gravities are also suitable to regularize Lovelock theories. The Wess-Zumino consistency condition ensures that anomalies of the generic form computed here should appear for these and other theories.

  1. AdS5×S(5) mirror model as a string sigma model.

    Science.gov (United States)

    Arutyunov, Gleb; van Tongeren, Stijn J

    2014-12-31

    Doing a double Wick rotation in the world sheet theory of the light cone AdS5×S(5) superstring results in an inequivalent, so-called mirror theory that plays a central role in the field of integrability in the AdS-CFT correspondence. We show that this mirror theory can be interpreted as the light cone theory of a free string on a different background. This background is related to dS5×H(5) by a double T-duality, and has hidden supersymmetry. The geometry can also be extracted from an integrable deformation of the AdS5×S(5) sigma model, and we prove the observed mirror duality of these deformed models at the bosonic level as a byproduct. While we focus on AdS5×S(5), our results apply more generally.

  2. Value-Added Business Based On Small Scale Of Fisheries A Case Study On Nortern And Shouthern Coasts Of Java Lamongan And Pelabuhanratu Regency Indonesia

    Directory of Open Access Journals (Sweden)

    Budi Wardono

    2015-08-01

    Full Text Available The development of fisheries sector is intended to improve the role of creating a strong linkage with other sectors by increasing the value added absorbing labor forces and increasing peoples income so that this can make the economy grow well. The value added is a value that increases due to a commodity that has been processed transported or stored in a production. Lamongan and Pelabuhanratu regencies are one of fisheries centers on the north and the south coast of Java Island. The aim of this research was to know the value added and the business margin of fisheries from the processing and marketing aspects. The research was carried out in two locations Northern coast Lamongan regencies and Shouther coasts Pelabuhanratu regencies Indoneisa. The data used were primary data the people involved in the business including fishing marketing and processing product. The results showed that the process of fisheries product yielded the value added and margin that were created from the incorporation of business benefit added input contribution other input and direct reward for the labor forces. The value added and the business margin of product processing can reach 2 to 3 fold from the main input value. The value added and the business margin of fisheries product processing were very big. This was the source of economy growth there. The effort to develop the business of fisheries product processing in the small scale need to be supported with various programs especially in the market access and funding.

  3. Half BPS states in AdS_5 x Y^{p,q}

    CERN Document Server

    Gava, Edi; Milanesi, Giuseppe; O'Loughlin, Martin

    2008-01-01

    We study a class of solutions of IIB Supergravity which are asymptotically AdS_5 x Y^{p,q}. They have an R x SO(4) x SU(2) x U(1) isometry and preserve half of the 8 supercharges of the background geometry. They are described by a set of second order differential equations that we have found and analysed in a previous paper, where we studied 1/8 BPS states in the maximally supersymmetric AdS_5 x S^5 background. These geometries correspond to certain chiral primary operators of the N=1 superconformal quiver theories, dual to IIB theory on AdS_5 x Y^{p,q}. We also show how to recover the AdS_5 x Y^{p,q} backgrounds by suitably doubling the number of preserved supersymmetries. We then solve the differential equations perturbatively in a large AdS_5 radius expansion, imposing asymptotic AdS_5 x Y^{p,q} boundary conditions. We compute the global baryonic and mesonic charges, including the R-charge. As for the computation of the mass, i.e. the conformal dimension D of the dual field theory operators, which is notor...

  4. Motion of particles on a four-dimensional asymptotically AdS black hole with scalar hair

    Energy Technology Data Exchange (ETDEWEB)

    Gonzalez, P.A.; Olivares, Marco [Universidad Diego Portales, Facultad de Ingenieria, Santiago (Chile); Vasquez, Yerko [Universidad de La Serena, Departamento de Fisica, Facultad de Ciencias, La Serena (Chile)

    2015-10-15

    Motivated by black hole solutions with matter fields outside their horizon, we study the effect of these matter fields on the motion of massless and massive particles. We consider as background a four-dimensional asymptotically AdS black hole with scalar hair. The geodesics are studied numerically and we discuss the differences in the motion of particles between the four-dimensional asymptotically AdS black holes with scalar hair and their no-hair limit, that is, Schwarzschild AdS black holes. Mainly, we found that there are bounded orbits like planetary orbits in this background. However, the periods associated to circular orbits are modified by the presence of the scalar hair. Besides, we found that some classical tests such as perihelion precession, deflection of light, and gravitational time delay have the standard value of general relativity plus a correction term coming from the cosmological constant and the scalar hair. Finally, we found a specific value of the parameter associated to the scalar hair, in order to explain the discrepancy between the theory and the observations, for the perihelion precession of Mercury and light deflection. (orig.)

  5. Motion of particles on a Four-Dimensional Asymptotically AdS Black Hole with Scalar Hair

    CERN Document Server

    Gonzalez, P A; Vasquez, Yerko

    2015-01-01

    Motivated by black hole solutions with matter fields outside their horizon, we study the effect of these matter fields in the motion of massless and massive particles. We consider as background a four-dimensional asymptotically AdS black hole with scalar hair. The geodesics are studied numerically and we discuss about the differences in the motion of particles between the four-dimensional asymptotically AdS black holes with scalar hair and their no-hair limit, that is, Schwarzschild AdS black holes. Mainly, we found that there are bounded orbits like planetary orbits in this background. However, the periods associated to circular orbits are modified by the presence of the scalar hair. Besides, we found that some classical tests such as perihelion precession, deflection of light and gravitational time delay have the standard value of general relativity plus a correction term coming from the cosmological constant and the scalar hair. Finally, we found a specific value of the parameter associated to the scalar h...

  6. Holographic Description of AdS Cosmologies

    CERN Document Server

    Hertog, T; Hertog, Thomas; Horowitz, Gary T.

    2005-01-01

    To gain insight in the quantum nature of the big bang, we study the dual field theory description of asymptotically anti-de Sitter solutions of supergravity that have cosmological singularities. The dual theories do not appear to have a stable ground state. One regularization of the theory causes the cosmological singularities in the bulk to turn into giant black holes with scalar hair. We interpret these hairy black holes in the dual field theory and use them to compute a finite temperature effective potential. In our study of the field theory evolution, we find no evidence for a "bounce" from a big crunch to a big bang. Instead, it appears that the big bang is a rare fluctuation from a generic equilibrium quantum gravity state.

  7. Study on the mortality in Ecuador related to dietary factors

    OpenAIRE

    Juan Alejandro Neira-Mosquera; Fernando Pérez-Rodríguez; Sungey Sánchez-Llaguno; Rafael Moreno Rojas

    2013-01-01

    Diet is an important factor related to the development of numerous diseases. In developing countries like Ecuador, this aspect is not considered as priority however, the study of the incidence of certain diet-related diseases could help to assess consumption habits of a country from a Public Health perspective and support national nutrition policies and programs. The objective the present study is to investigate the mortality rate of certain diet-related diseases in Ecuador and its possible r...

  8. Introduction to AdS-CFT

    CERN Document Server

    Nastase, Horatiu

    2007-01-01

    These lectures present an introduction to AdS-CFT, and are intended both for begining and more advanced graduate students, which are familiar with quantum field theory and have a working knowledge of their basic methods. Familiarity with supersymmetry, general relativity and string theory is helpful, but not necessary, as the course intends to be as self-contained as possible. I will introduce the needed elements of field and gauge theory, general relativity, supersymmetry, supergravity, strings and conformal field theory. Then I describe the basic AdS-CFT scenario, of ${\\cal N}=4 $ Super Yang-Mills's relation to string theory in $AdS_5\\times S_5$, and applications that can be derived from it: 3-point functions, quark-antiquark potential, finite temperature and scattering processes, the pp wave correspondence and spin chains. I also describe some general properties of gravity duals of gauge theories.

  9. Early AD pathology in a [C-11]PiB-negative case: a PiB-amyloid imaging, biochemical, and immunohistochemical study.

    Science.gov (United States)

    Ikonomovic, Milos D; Abrahamson, Eric E; Price, Julie C; Hamilton, Ronald L; Mathis, Chester A; Paljug, William R; Debnath, Manik L; Cohen, Anne D; Mizukami, Katsuyoshi; DeKosky, Steven T; Lopez, Oscar L; Klunk, William E

    2012-03-01

    Amyloid-β (Aβ) deposits are detectable in the brain in vivo using positron emission tomography (PET) and [C-11]-labeled Pittsburgh Compound B ([C-11]PiB); however, the sensitivity of this technique is not well understood. In this study, we examined Aβ pathology in an individual who had clinical diagnoses of probable dementia with Lewy bodies and possible Alzheimer's disease (AD) but with no detectable [C-11]PiB PET retention ([C-11]PiB(-)) when imaged 17 months prior to death. Brain samples were processed in parallel with region-matched samples from an individual with a clinical diagnosis of probable AD and a positive [C-11]PiB PET scan ([C-11]PiB(+)) when imaged 10 months prior to death. In the [C-11]PiB(-) case, Aβ plaques were sparse, occupying less than 2% cortical area, and were weakly labeled with 6-CN-PiB, a highly fluorescent derivative of PiB. In contrast, Aβ plaques occupied up to 12% cortical area in the [C-11]PiB(+) case, and were intensely labeled with 6-CN-PIB. The [C-11]PiB(-) case had low levels of [H-3]PiB binding (PiB(+) case (800-1, 700 pmol/g). In several cortical regions of the [C-11]PiB(-) case, Aβ1-40 levels were within the range of cortical Aβ1-40 values in the [C-11]PiB(+) case. Antemortem [C-11]PiB DVR values correlated well with region-matched postmortem measures of Aβ1-42 and Aβ1-40 in the [C-11]PiB(+), and with Aβ1-42 only in the [C-11]PiB(-) case. The low ratios of [H-3]PiB binding levels to Aβ concentrations and 6-CN-PiB to Aβ plaque loads in the [C-11]PiB(-) case indicate that Aβ pathology in the brain may be associated with low or undetectable levels of [C-11]PiB retention. Studies in greater numbers of [C-11]PiB PET autopsy cases are needed to define the Aβ concentration and [H-3]PiB binding levels required to produce a positive [C-11]PiB PET signal.

  10. A Crossing-Symmetric Phase for $AdS_{5} x S^{5}$ Strings

    CERN Document Server

    Beisert, N; López, E; Beisert, Niklas; Hernandez, Rafael; Lopez, Esperanza

    2006-01-01

    We propose an all-order perturbative expression for the dressing phase of the AdS_5 x S^5 string S-matrix at strong coupling. Moreover, we are able to sum up large parts of this expression. This allows us to start the investigation of the analytic structure of the phase at finite coupling revealing a few surprising features. The phase obeys all known constraints including the crossing relation and it matches with the known physical data at strong coupling. In particular, we recover the bound states of giant magnons recently found by Hofman and Maldacena as poles of the scattering matrix. At weak coupling our proposal seems to differ with gauge theory. A possible solution to this disagreement is the inclusion of additional pieces in the phase not contributing to crossing, which we also study.

  11. Towards Timelike Singularity via AdS Dual

    CERN Document Server

    Bhowmick, Samrat

    2016-01-01

    It is well known that Kasner geometry with spacelike singularity can be extended to bulk AdS-like geometry, furthermore one can study field theory on this Kasner space via its gravity dual. In this paper, we show that there exists a Kasner-like geometry with timelike singularity for which one can construct a dual gravity description. We then study various minimal surfaces including spacelike geodesics. Finally, we compute correlators of highly massive operators in the boundary field theory with a geodesic approximation.

  12. Protein domain organisation: adding order

    Directory of Open Access Journals (Sweden)

    Kummerfeld Sarah K

    2009-01-01

    Full Text Available Abstract Background Domains are the building blocks of proteins. During evolution, they have been duplicated, fused and recombined, to produce proteins with novel structures and functions. Structural and genome-scale studies have shown that pairs or groups of domains observed together in a protein are almost always found in only one N to C terminal order and are the result of a single recombination event that has been propagated by duplication of the multi-domain unit. Previous studies of domain organisation have used graph theory to represent the co-occurrence of domains within proteins. We build on this approach by adding directionality to the graphs and connecting nodes based on their relative order in the protein. Most of the time, the linear order of domains is conserved. However, using the directed graph representation we have identified non-linear features of domain organization that are over-represented in genomes. Recognising these patterns and unravelling how they have arisen may allow us to understand the functional relationships between domains and understand how the protein repertoire has evolved. Results We identify groups of domains that are not linearly conserved, but instead have been shuffled during evolution so that they occur in multiple different orders. We consider 192 genomes across all three kingdoms of life and use domain and protein annotation to understand their functional significance. To identify these features and assess their statistical significance, we represent the linear order of domains in proteins as a directed graph and apply graph theoretical methods. We describe two higher-order patterns of domain organisation: clusters and bi-directionally associated domain pairs and explore their functional importance and phylogenetic conservation. Conclusion Taking into account the order of domains, we have derived a novel picture of global protein organization. We found that all genomes have a higher than expected

  13. The effect of Ad

    Institute of Scientific and Technical Information of China (English)

    李小艳

    2010-01-01

    There is the trend that now people appreciate those who are slim and regard slim even thin people beautiful. The thinner a person is, the more beautiful. Women, born to pursuit beauty, try various means to follow the trend. We all watch TV, and find a lot of advertisements on diet. The effect of them is tremendous. We all know the fact that it is not at all the better mouse trap will catch mouse. The sales methods are more important. If an advertisement is very interesting and seemingly effective, people will be lured by the ad and then try some of the products.

  14. Management job ads

    DEFF Research Database (Denmark)

    2014-01-01

    The article asks whether it is not the responsibility of corporations to address the issue of women being underrepresented in Danish management jobs. In other words, it is argued that corporations should be encouraged to engage more actively in the recruitment of both men and women for management...... that this agreement reflects a high degree of conservatism in the system where men enjoy a considerable advantage and where procedures that ensure male dominance are perpetuated even in the linguistic and discursive construction of job ads....

  15. The concept of added value of FM

    DEFF Research Database (Denmark)

    2012-01-01

    Purpose: This chapter presents research perspectives and theoretical reflections on the concept of added value of FM from a variety of academic fields. Methodology: A literature review of the most influential journals within the academic fields of Facilities Management (FM), Corporate Real Estate...... conceptualization of the concept of added value of FM is of utmost importance for further research into the added value of FM and well-considered, evidence- based Value Adding Management in practice. Research limitations: Due to limited time not all FM-related journals could be included in the literature review...... Management (CREM) and Business to Business Marketing (B2B Marketing). Findings: The research shows different definitions and focus points, dependent on the academic field and the area of application. The different research perspectives explored a holistic view on the added value of FM by the integration...

  16. Metastability in bubbling AdS space

    Science.gov (United States)

    Massai, Stefano; Pasini, Giulio; Puhm, Andrea

    2015-02-01

    We study the dynamics of probe M5 branes with dissolved M2 charge in bubbling geometries with SO(4) × SO(4) symmetry. These solutions were constructed by Bena-Warner and Lin-Lunin-Maldacena and correspond to the vacua of the maximally supersymmetric mass-deformed M2 brane theory. We find that supersymmetric probe M2 branes polarize into M5 brane shells whose backreaction creates an additional bubble in the geometry. We explicitly check that the supersymmetric polarization potential agrees with the one found within the Polchinski-Strassler approximation. The main result of this paper is that probe M2 branes whose orientation is opposite to the background flux can polarize into metastable M5 brane shells. These decay to a supersymmetric configuration via brane-flux annihilation. Our findings suggest the existence of metastable states in the mass-deformed M2 brane theory.

  17. Metastability in Bubbling AdS Space

    CERN Document Server

    Massai, Stefano; Puhm, Andrea

    2014-01-01

    We study the dynamics of probe M5 branes with dissolved M2 charge in bubbling geometries with SO(4) x SO(4) symmetry. These solutions were constructed by Bena-Warner and Lin-Lunin-Maldacena and correspond to the vacua of the maximally supersymmetric mass-deformed M2 brane theory. We find that supersymmetric probe M2 branes polarize into M5 brane shells whose backreaction creates an additional bubble in the geometry. We explicitly check that the supersymmetric polarization potential agrees with the one found within the Polchinski-Strassler approximation. The main result of this paper is that probe M2 branes whose orientation is opposite to the background flux can polarize into metastable M5 brane shells. These decay to a supersymmetric configuration via brane-flux annihilation. Our findings suggest the existence of metastable states in the mass-deformed M2 brane theory.

  18. Joint assessment of white matter integrity, cortical and subcortical atrophy to distinguish AD from behavioral variant FTD: A two-center study

    Directory of Open Access Journals (Sweden)

    Christiane Möller

    2015-01-01

    Full Text Available We investigated the ability of cortical and subcortical gray matter (GM atrophy in combination with white matter (WM integrity to distinguish behavioral variant frontotemporal dementia (bvFTD from Alzheimer's disease (AD and from controls using voxel-based morphometry, subcortical structure segmentation, and tract-based spatial statistics. To determine which combination of MR markers differentiated the three groups with the highest accuracy, we conducted discriminant function analyses. Adjusted for age, sex and center, both types of dementia had more GM atrophy, lower fractional anisotropy (FA and higher mean (MD, axial (L1 and radial diffusivity (L23 values than controls. BvFTD patients had more GM atrophy in orbitofrontal and inferior frontal areas than AD patients. In addition, caudate nucleus and nucleus accumbens were smaller in bvFTD than in AD. FA values were lower; MD, L1 and L23 values were higher, especially in frontal areas of the brain for bvFTD compared to AD patients. The combination of cortical GM, hippocampal volume and WM integrity measurements, classified 97–100% of controls, 81–100% of AD and 67–75% of bvFTD patients correctly. Our results suggest that WM integrity measures add complementary information to measures of GM atrophy, thereby improving the classification between AD and bvFTD.

  19. Open string fluctuations in AdS space with and without torsion

    DEFF Research Database (Denmark)

    Larsen, A.L.; Lomholt, Michael Andersen

    2003-01-01

    dangerous than expected in these cases. The general formalism can be straightforwardly used also to study the (bosonic part of the) fluctuations around the closed strings, recently considered in connection with the AdS/conformal field theory duality, on AdS ×S and AdS ×S ×T . © 2003 The American Physical......The equations of motion and boundary conditions for the fluctuations around a classical open string, in a curved space-time with torsion, are considered in compact and world-sheet covariant form. The rigidly rotating open strings in anti-de Sitter space with and without torsion are investigated...

  20. Study of Mothers' Anxieties Related to Their Children's Future

    Science.gov (United States)

    Ilgar, Sengul

    2015-01-01

    The purpose of this study is to study anxieties of mothers related to their children's future. Qualitative method was used in order to study anxieties of mothers from different socio-economic levels. Sample of the study participants are 129 mothers living in Istanbul. 32 of those mothers are from upper socio-economic level, 57, from middle…

  1. Study on the fermentation properties of added flammulina velutipes juice yogurt%金针菇汁酸奶的发酵特性研究

    Institute of Scientific and Technical Information of China (English)

    刘昭明; 黄翠姬; 苏小娟

    2009-01-01

    Several factors were studied in the fermentation and storage process of flammulina velutipes juice yogurt, including changes of pH, titrable acidity (TA) values, amount of lactic acid and diacetyl and lactobacillus. And the content of amino acids was also measured. The results showed that: when the adding amount of Flammulina velutipes juice was excess 10%, the curd time was shorter and curd quality was better; during the fermentation, the decreasing rate of pH, increasing rate of TA, the amount of lactic acid and diacetyl in the flammulina velutipes juice yogurt were quicker than the controlled sample; in the end of fermentation, the amount of lactic acid tend to be consistent, and the amount of diacetyl increased with the amount of juice; during the storage, when the adding amount of flammulina velutipes juice was excess 10%, the TA value increased slowly, while the laetobacillus decreased slowly. The content of amino acids of yogurt, with juice 10% adding, was excess 12% than the controlled sample. It was concluded that the flammulina velutipes juice was able to promote the growth of lactobacillus and inhibit the post--acidification of yogurt, and the yogurt with flammulina velutipes juice has high nutritional value.%研究金针菇汁酸奶在发酵及贮藏过程中的pH值、滴定酸度、乳酸含量、丁二酮含量和乳酸菌总数的变化以及金针菇汁酸奶的氨基酸含量.结果表明:菇汁添加量为10%以上时,酸奶凝乳时间缩短,凝乳效果好于对照样;发酵过程中,添加菇汁的酸奶的pH值下降的速度、滴定酸度、乳酸及丁二酮增加的速度大于对照样,最终乳酸的含量趋于一致,而丁二酮的含量则是菇汁添加量越大,发酵结束时的含量也越大;菇汁添加量为10%以上时,酸奶在贮藏过程中,滴定酸度增加比较缓慢,乳酸菌总数下降较少;菇汁添加量10%的酸奶的氨基酸含量超过对照样12%.说明菇汁的添加促进了乳酸菌的生长,可以在一

  2. Predictors of compliance with a home-based exercise program added to usual medical care in preventing postmenopausal osteoporosis: an 18-month prospective study.

    Science.gov (United States)

    Mayoux-Benhamou, M A; Roux, C; Perraud, A; Fermanian, J; Rahali-Kachlouf, H; Revel, M

    2005-03-01

    This prospective 18-month study was designed to assess long-term compliance with a program of exercise aimed to prevent osteoporosis after an educational intervention and to uncover determinants of compliance. A total of 135 postmenopausal women were recruited by flyers or instructed by their physicians to participate in an educational session added to usual medical care. After a baseline visit and dual-energy X-ray absorptiometry, volunteers participated in a 1-day educational session consisting of a lecture and discussion on guidelines for appropriate physical activity and training in a home-based exercise program taught by a physical therapist. Scheduled follow-up visits were 1, 6, and 18 months after the educational session. Compliance with the exercise program was defined as an exercise practice rate 50% or greater than the prescribed training. The 18-month compliance rate was 17.8% (24/135). The main reason for withdrawal from the program was lack of motivation. Two variables predicted compliance: contraindication for hormone replacement therapy (odds ratio [OR] = 0.13; 95% confidence interval [95% CI], 0.04 to 0.46) and general physical function scores from an SF-36 questionnaire (OR=1.26; 95% CI, 1.03 to 1.5). To a lesser extent, osteoporosis risk, defined as a femoral T-score exercise, only a minority of postmenopausal women adhered to a home-based exercise program after 18 months.

  3. Efficacy and safety of pioglitazone added to alogliptin in Japanese patients with type 2 diabetes mellitus: a multicentre, randomized, double-blind, parallel-group, comparative study.

    Science.gov (United States)

    Kaku, K; Katou, M; Igeta, M; Ohira, T; Sano, H

    2015-12-01

    A phase IV, multicentre, randomized, double-blind, parallel-group, comparative study was conducted in Japanese subjects with type 2 diabetes mellitus (T2DM) who had inadequate glycaemic control, despite treatment with alogliptin in addition to diet and/or exercise therapy. Subjects with glycated haemoglobin (HbA1c) concentrations of 6.9-10.5% were randomized to receive 16 weeks' double-blind treatment with pioglitazone 15 mg, 30 mg once daily or placebo added to alogliptin 25 mg once daily. The primary endpoint was the change in HbA1c from baseline at the end of treatment period (week 16). Both pioglitazone 15 and 30 mg combination therapy resulted in a significantly greater reduction in HbA1c than alogliptin monotherapy [-0.80 and -0.90% vs 0.00% (the least squares mean using analysis of covariance model); p Pioglitazone/alogliptin combination therapy was effective and generally well tolerated in Japanese subjects with T2DM and is considered to be useful in clinical settings.

  4. Preliminary design studies of a 100 MeV H-/H+ LINAC as injector for SNS synchrotron/ADS LINAC

    Indian Academy of Sciences (India)

    S A Pande; Moonooku Prasad; Nita Kulkarni; P R Hannurkar

    2002-11-01

    It is proposed to construct a spallation neutron source (SNS) at Centre for Advanced Technology (CAT) based on a 1 GeV proton synchrotron with 100 MeV H- LINAC as injector. Additionally, the LINAC can form the first 100 MeV part of a 1 GeV proton LINAC to be built in future for accelerator driven system (ADS) applications. We are exploring a configuration of the 100 MeV LINAC which will consist of an H- ion source, a 4–6 MeV RFQ followed either by a 20 MeV drift tube LINAC (DTL) and 100 MeV separated function drift tube LINAC (SDTL) or a coupled cavity drift tube LINAC (CCDTL) structure. In this paper, we present the results of our preliminary physics design studies of the RFQ–SDTL, RFQ–CCDTL and RFQ–DTL–SDTL configurations. The design of the 4.5 MeV RFQ is discussed along with the matching sections between the RFQ–SDTL/DTL and RFQ–CCDTL. The choice of the accelerator configuration and that of various parameters of the individual accelerator structures under consideration are discussed. The design objectives are to arrive at a configuration which eases heat removal for CW operation and which is less prone to halo formation in order to reduce the beam loss at higher energies.

  5. A Simulation Study: The Impact of Random and Realistic Mobility Models on the Performance of Bypass-AODV in Ad Hoc Wireless Networks

    Directory of Open Access Journals (Sweden)

    Baroudi Uthman

    2010-01-01

    Full Text Available To bring VANET into reality, it is crucial to devise routing protocols that can exploit the inherited characteristics of VANET environment to enhance the performance of the running applications. Previous studies have shown that a certain routing protocol behaves differently under different presumed mobility patterns. Bypass-AODV is a new optimization of the AODV routing protocol for mobile ad-hoc networks. It is proposed as a local recovery mechanism to enhance the performance of the AODV routing protocol. It shows outstanding performance under the Random Waypoint mobility model compared with AODV. However, Random Waypoint is a simple model that may be applicable to some scenarios but it is not sufficient to capture some important mobility characteristics of scenarios where VANETs are deployed. In this paper, we will investigate the performance of Bypass-AODV under a wide range of mobility models including other random mobility models, group mobility models, and vehicular mobility models. Simulation results show an interesting feature that is the insensitivity of Bypass-AODV to the selected random mobility model, and it has a clear performance improvement compared to AODV. For group mobility model, both protocols show a comparable performance, but for vehicular mobility models, Bypass-AODV suffers from performance degradation in high-speed conditions.

  6. Study the Effect of Value-Added of Services Sector on Forecasting of Electricity Demand in Services Sector due to Price Reform

    Directory of Open Access Journals (Sweden)

    Sayed Mahdi Mostafavi

    2016-07-01

    Full Text Available Electrical energy is as one of the important effective factors on economic growth and development. In recent decades, numerous studies in different countries to estimate and forecast electricity demand in different parts of the economy have been made. In this paper, using the method ARDL, estimation and forecasting of electricity demand in the services sector of Iran are determined for the time period from 1983 to 2012. Estimated equations show that the added value of the services sector and a significant positive impact on the demand for electricity in this sector. The price elasticity for services sector is smaller than 1 due to low electricity prices and subsidized electricity. Hence, electricity prices have little impact on the demand for electricity. The results of the estimate represents a long-term relationship between the variables in the services sector. In this paper, based on amendments to the law on subsidies and estimated values, anticipated electricity demand until the end of the fifth development plan was carried out. The results indicate an increase in power consumption in the services sector.

  7. Reggeon exchange from AdS/CFT

    CERN Document Server

    Janik, R A

    2002-01-01

    Using the AdS/CFT correspondence in a confining backgroundand the worldline formalism of gauge field theories,we compute scattering amplitudes with an exchange of quark andantiquark in the $t$-channel corresponding to Reggeon exchange. Itrequires going beyond the eikonal approximation, which was used when studying Pomeron exchange. The wordline path integral is evaluated through the determination of minimal surfaces and their boundaries by the saddle-point method at large gauge coupling g^2N_c. We find a Regge behaviour with linear Regge trajectories. The slope is related to the $q\\bar q$ static potential and is four times the Pomeronslope obtained in the same framework. A contribution to the intercept, related to the L\\"uscher term, comes from the fluctuations around the minimal surface.

  8. Model Catalysis of Ammonia Synthesis ad Iron-Water Interfaces - ASum Frequency Generation Vibrational Spectroscopic Study of Solid-GasInterfaces and Anion Photoelectron Spectroscopic Study of Selected Anionclusters

    Energy Technology Data Exchange (ETDEWEB)

    Ferguson, Michael James [Univ. of California, Berkeley, CA (United States)

    2005-01-01

    The ammonia synthesis reaction has been studied using single crystal model catalysis combined with sum frequency generation (SFG) vibrational spectroscopy. The adsorption of gases N2, H2, O2 and NH3 that play a role in ammonia synthesis have been studied on the Fe(111) crystal surface by sum frequency generation vibrational spectroscopy using an integrated Ultra-High Vacuum (UHV)/high-pressure system. SFG spectra are presented for the dissociation intermediates, NH2 (~3325 cm-1) and NH (~3235 cm-1) under high pressure of ammonia or equilibrium concentrations of reactants and products on Fe(111) surfaces. Special attention was paid to understand how potassium promotion of the iron catalyst affects the intermediates of ammonia synthesis. An Fe(111) surface promoted with 0.2 monolayers of potassium red shifts the vibrational frequencies of the reactive surface intermediates, NH and NH2, providing evidence for weakened the nitrogen-hydrogen bonds relative to clean Fe(111). Spectral features of these surface intermediates persisted to higher temperatures for promoted iron surfaces than for clean Fe(111) surfaces implying that nitrogen-iron bonds are stronger for the promoted surface. The ratio of the NH to NH2 signal changed for promoted surfaces in the presence of equilibrium concentrations of reactants and products. The order of adding oxygen and potassium to promoted surfaces does not alter the spectra indicating that ammonia induces surface reconstruction of the catalyst to produce the same surface morphology. When oxygen is co-adsorbed with nitrogen, hydrogen, ammonia or potassium on Fe(111), a relative phase shift of the spectra occurs as compared to the presence of adsorbates on clean iron surfaces. Water adsorption on iron was also probed using SFG vibrational spectroscopy. For both H2O and D2O, the only spectral feature was in the range of

  9. Time-dependent spacetimes in AdS/CFT: Bubble and black hole

    CERN Document Server

    Ross, S F; Ross, Simon F.; Titchener, Georgina

    2005-01-01

    We extend the study of time-dependent backgrounds in the AdS/CFT correspondence by examining the relation between bulk and boundary for the smooth 'bubble of nothing' solution and for the locally AdS black hole which has the same asymptotic geometry. These solutions are asymptotically locally AdS, with a conformal boundary conformal to de Sitter space cross a circle. We study the cosmological horizons and relate their thermodynamics in the bulk and boundary. We consider the alpha-vacuum ambiguity associated with the de Sitter space, and find that only the Euclidean vacuum is well-defined on the black hole solution. We argue that this selects the Euclidean vacuum as the preferred state in the dual strongly coupled CFT.

  10. Impact of the AD 79 explosive eruption on Pompeii, I. Relations amongst the depositional mechanisms of the pyroclastic products, the framework of the buildings and the associated destructive events

    Science.gov (United States)

    Luongo, Giuseppe; Perrotta, Annamaria; Scarpati, Claudio

    2003-08-01

    A quantitative and qualitative evaluation of the damage caused by the products of explosive eruptions to buildings provides an excellent contribution to the understanding of the various eruptive processes during such dramatic events. To this end, the impact of the products of the two main phases (pumice fallout and pyroclastic density currents) of the Vesuvius AD 79 explosive eruption onto the Pompeii buildings has been evaluated. Based on different sources of data, such as photographs and documents referring to the archaeological excavations of Pompeii, the stratigraphy of the pyroclastic deposits, and in situ inspection of the damage suffered by the buildings, the present study has enabled the reconstruction of the events that occurred inside the city when the eruption was in progress. In particular, we present new data related to the C.J. Polibius' house, a large building located inside Pompeii. From a comparison of all of the above data sets, it has been possible to reconstruct, in considerable detail, the stratigraphy of the pyroclastic deposits accumulated in the city, to understand the direction of collapse of the destroyed walls, and to evaluate the stratigraphic level at which the walls collapsed. Finally, the distribution and style of the damage allow us to discuss how the emplacement mechanisms of the pyroclastic currents are influenced by their interaction with the urban centre. All the data suggest that both structure and shape of the town buildings affected the transport and deposition of the erupted products. For instance, sloping roofs 'drained' a huge amount of fall pumice into the 'impluvia' (a rectangular basin in the centre of the hall with the function to collect the rain water coming from a hole in the centre of the roof), thus producing anomalous deposit thicknesses. On the other hand, flat and low-sloping roofs collapsed under the weight of the pyroclastic material produced during the first phase of the eruption (pumice fall). In addition

  11. [Rapid analysis of added ingredients in heroin].

    Science.gov (United States)

    Wang, Ji-fen; Yu, Jing; Guo, Xin; Sun, Xing-long; Wang, Ding-fang

    2011-07-01

    The method of rapid analysis of added ingredients in heroin was studied in the present paper. Adding sucrose, fructose, glucose, starch, caffeine and phenacetin to heroin with a certain percentage, the changes in the infrared spectrum with the concentration of heroin increasing and the detection limit of the additives were determined. Whether or not heroin can be detected in the sample with high concentration of added ingredients was studied using Raman spectroscopy. Similarly, in high purity of heroin, whether or not Raman spectroscopy can detect the added ingredients was tested. Through systematic experiments, the results showed that: using infrared spectroscopy and Raman spectroscopy to test the added ingredients of heroin is a rapid and effective method. Each has both advantages and disadvantages. We should select the appropriate method according to the actual cases.

  12. Holography in 3D AdS gravity with torsion

    CERN Document Server

    Blagojević, Milutin; Miskovic, Olivera; Olea, Rodrigo

    2013-01-01

    Basic aspects of the AdS/CFT correspondence are studied in the framework of 3-dimensional gravity with torsion. After choosing a consistent holographic ansatz, we formulate an improved approach to the Noether--Ward identities for the boundary theory. The method is applied first to the topological Mielke--Baekler model, and then to the more interesting (parity-preserving) 3-dimensional gravity with propagating torsion. In both cases, we find the finite holographic energy-momentum and spin currents and obtain the associated (anomalous) Noether--Ward identities.

  13. Canonical energy and hairy AdS black holes

    CERN Document Server

    Hyun, Seungjoon; Yi, Sang-Heon

    2016-01-01

    We propose the modified version of the canonical energy which was introduced originally by Hollands and Wald. Our construction depends only on the Euler-Lagrange expression of the system and thus is independent of the ambiguity in the Lagrangian. After some comments on our construction, we briefly mention on the relevance of our construction to the boundary information metric in the context of the AdS/CFT correspondence. We also study the stability of three-dimensional hairy extremal black holes by using our construction.

  14. On Thermodynamics of AdS Black Holes in M-Theory

    CERN Document Server

    Belhaj, A; Moumni, H EL; Masmar, K; Sedra, M B

    2015-01-01

    Motivated by a recent work on asymptotically AdS_4 black holes in M-theory, we investigate the thermodynamics and thermodynamical geometry of AdS black holes from M2 and M5-branes. Concretely, we consider AdS black holes in AdS_{p+2}\\times S^{11-p-2}, where p=2,5 by interpreting the number of M2 (and M5-branes) as a thermodynamical variable. We study the corresponding phase transition to examine their stabilities by calculating and discussing various thermodynamical quantities including the chemical potential. Then, we compute the thermodynamical curvatures from the Quevedo metric for M2 and M5-branes geometries to reconsider the stability of such black objects. The Quevedo metric singularities recover similar stability results provided by the phase transition program.

  15. Does an eye-hand coordination test have added value as part of talent identification in table tennis? A validity and reproducibility study.

    Science.gov (United States)

    Faber, Irene R; Oosterveld, Frits G J; Nijhuis-Van der Sanden, Maria W G

    2014-01-01

    This study investigated the added value, i.e. discriminative and concurrent validity and reproducibility, of an eye-hand coordination test relevant to table tennis as part of talent identification. Forty-three table tennis players (7-12 years) from national (n = 13), regional (n = 11) and local training centres (n = 19) participated. During the eye-hand coordination test, children needed to throw a ball against a vertical positioned table tennis table with one hand and to catch the ball correctly with the other hand as frequently as possible in 30 seconds. Four different test versions were assessed varying the distance to the table (1 or 2 meter) and using a tennis or table tennis ball. 'Within session' reproducibility was estimated for the two attempts of the initial tests and ten youngsters were retested after 4 weeks to estimate 'between sessions' reproducibility. Validity analyses using age as covariate showed that players from the national and regional centres scored significantly higher than players from the local centre in all test versions (ptennis ball at 1 meter showed the highest association (r = 0.54; p = 0.001). Differences between the first and second attempts were comparable for all test versions (between -8 and +7 repetitions) with ICC's ranging from 0.72 to 0.87. The smallest differences were found for the test with a table tennis ball at 1 meter (between -3 and +3 repetitions). Best test version as part of talent identification appears to be the version with a table tennis ball at 1 meter regarding the psychometric characteristics evaluated. Longitudinal studies are necessary to evaluate the predictive value of this test.

  16. Does an eye-hand coordination test have added value as part of talent identification in table tennis? A validity and reproducibility study.

    Directory of Open Access Journals (Sweden)

    Irene R Faber

    Full Text Available This study investigated the added value, i.e. discriminative and concurrent validity and reproducibility, of an eye-hand coordination test relevant to table tennis as part of talent identification. Forty-three table tennis players (7-12 years from national (n = 13, regional (n = 11 and local training centres (n = 19 participated. During the eye-hand coordination test, children needed to throw a ball against a vertical positioned table tennis table with one hand and to catch the ball correctly with the other hand as frequently as possible in 30 seconds. Four different test versions were assessed varying the distance to the table (1 or 2 meter and using a tennis or table tennis ball. 'Within session' reproducibility was estimated for the two attempts of the initial tests and ten youngsters were retested after 4 weeks to estimate 'between sessions' reproducibility. Validity analyses using age as covariate showed that players from the national and regional centres scored significantly higher than players from the local centre in all test versions (p<0.05. The tests at 1 meter demonstrated better discriminative ability than those at 2 meter. While all tests but one had a positive significant association with competition outcome, which were corrected for age influences, the version with a table tennis ball at 1 meter showed the highest association (r = 0.54; p = 0.001. Differences between the first and second attempts were comparable for all test versions (between -8 and +7 repetitions with ICC's ranging from 0.72 to 0.87. The smallest differences were found for the test with a table tennis ball at 1 meter (between -3 and +3 repetitions. Best test version as part of talent identification appears to be the version with a table tennis ball at 1 meter regarding the psychometric characteristics evaluated. Longitudinal studies are necessary to evaluate the predictive value of this test.

  17. A Relational Approach to the Study of Religious Survival Units

    DEFF Research Database (Denmark)

    Reeh, Niels

    2012-01-01

    , a religion can be defined and studied as the result of complex set of dynamic relations, where a central tenet of a religion is that it relates to the significant religious other. As such religion is not a stable phenomenon but embedded in a dynamic historical process, which can explain the difficulties...

  18. Horizon Conformal Field Theories from $AdS_2$ Black Holes

    CERN Document Server

    Halyo, Edi

    2015-01-01

    We show that the very near horizon region of nonextreme black holes, which can be described by horizon CFTs, are related to $AdS_2$ Rindler spaces. The latter are $AdS_2$ black holes with specific masses and can be described by states of either $D=1$ or $D=2$ CFTs. The central charges of these CFTs and the conformal weights of their states that correspond to the nonextreme black holes exactly match those predicted by the horizon CFTs, providing supporting evidence for this description.

  19. Chaos and hydrodynamics near AdS$_2$

    CERN Document Server

    Jensen, Kristan

    2016-01-01

    We revisit AdS$_2$ holography with the Sachdev-Ye-Kitaev models in mind. Our main result is to rewrite a generic theory of gravity near an AdS$_2$ throat as a novel hydrodynamics coupled to the correlation functions of a conformal quantum mechanics. This gives a prescription for the computation of $n$-point functions in the dual quantum mechanics. We thereby find that the dual is maximally chaotic.

  20. Quantum Field Theory and Unification in AdS5

    CERN Document Server

    Randall, Lisa; Randall, Lisa; Schwartz, Matthew D.

    2001-01-01

    We consider gauge bosons in the bulk of AdS5 in a two-brane theory that addresses the hierarchy problem. We show such a theory can be consistent with gauge coupling unification at a high scale. We discuss subtleties in this calculation and show how to regulate consistently in a bounded AdS5 background. Our regularization is guided by the holographic dual of the calculation.

  1. Extended supersymmetric sigma models in AdS_4 from projective superspace

    CERN Document Server

    Butter, Daniel; Lindstrom, Ulf; Tartaglino-Mazzucchelli, Gabriele

    2012-01-01

    There exist two superspace approaches to describe N=2 supersymmetric nonlinear sigma models in four-dimensional anti-de Sitter (AdS_4) space: (i) in terms of N=1 AdS chiral superfields, as developed in arXiv:1105.3111 and arXiv:1108.5290; and (ii) in terms of N=2 polar supermultiplets using the AdS projective-superspace techniques developed in arXiv:0807.3368. The virtue of the approach (i) is that it makes manifest the geometric properties of the N=2 supersymmetric sigma-models in AdS_4. The target space must be a non-compact hyperkahler manifold endowed with a Killing vector field which generates an SO(2) group of rotations on the two-sphere of complex structures. The power of the approach (ii) is that it allows us, in principle, to generate hyperkahler metrics as well as to address the problem of deformations of such metrics. Here we show how to relate the formulation (ii) to (i) by integrating out an infinite number of N=1 AdS auxiliary superfields and performing a superfield duality transformation. We al...

  2. AdS-Sliced Flavor Branes and Adding Flavor to the Janus Solution

    CERN Document Server

    Clark, Adam B; Newman, George M; Rommal, Andrea

    2014-01-01

    We implement D7 flavor branes in AdS-sliced coordinates on $AdS_5\\times S^5$ with the ansatz that the brane fluctuates only in the warped ($\\mu$) direction in this slicing, which is particularly appropriate for studying the Janus solution. The natural field theory dual in this slicing is $\\mathcal{N}=4$ super Yang-Mills on two copies of $AdS_4$. Branes extending from $\\mu=\\pm\\pi/2$ can end at different locations, giving rise to quarks with piecewise constant mass on each $AdS_4$ half-space, jumping discontinuously between them. A second class of flavor brane solutions exists in this coordinate system, dubbed "continuous" flavor branes, that extend across the entire range of $\\mu$. We propose that the correct dual interpretation of "disconnected" flavor brane in this ansatz is a quark hypermultiplet with constant mass on one of the AdS$_4$ half-spaces with totally reflecting boundary conditions at the boundary of AdS$_4$; whereas the dual interpretation of a continuous flavor brane has totally transparent boun...

  3. The study of genetic polymorphisms related to serotonin in Alzheimer's disease: a new perspective in a heterogenic disorder

    Directory of Open Access Journals (Sweden)

    Oliveira J.R.M.

    1999-01-01

    Full Text Available Genetic and environmental factors have been implicated in the development of Alzheimer's disease (AD, the most common form of dementia in the elderly. Mutations in 3 genes mapped on chromosomes 21, 14 and 1 are related to the rare early onset forms of AD while the e4 allele of the apolipoprotein E (APOE gene (on chromosome 19 is the major susceptibility locus for the most common late onset AD (LOAD. Serotonin (5-hydroxytryptamine or 5-HT is a key neurotransmitter implicated in the control of mood, sleep, appetite and a variety of traits and behaviors. Recently, a polymorphism in the transcriptional control region upstream of the 5-HT transporter (5-HTT gene has been studied in several psychiatric diseases and personality traits. It has been demonstrated that the short variant(s of this 5-HTT gene-linked polymorphic region (5-HTTLPR is associated with a different transcriptional efficiency of the 5-HTT gene promoter resulting in decreased 5-HTT expression and 5-HT uptake in lymphocytes. An increased frequency of this 5-HTTLPR short variant polymorphism in LOAD was recently reported. In addition, another common polymorphic variation in the 5-HT2A and 5-HT2C serotonin receptor genes previously analyzed in schizophrenic patients was associated with auditory and visual hallucinations in AD. These observations suggest that the involvement of the serotonin pathway might provide an explanation for some aspects of the affective symptoms commonly observed in AD patients. In summary, research on genetic polymorphisms related to AD and involved in receptors, transporter proteins and the enzymatic machinery of serotonin might enhance our understanding of this devastating neurodegenerative disorder.

  4. The study of genetic polymorphisms related to serotonin in Alzheimer's disease: a new perspective in a heterogenic disorder.

    Science.gov (United States)

    Oliveira, J R; Zatz, M

    1999-04-01

    Genetic and environmental factors have been implicated in the development of Alzheimer's disease (AD), the most common form of dementia in the elderly. Mutations in 3 genes mapped on chromosomes 21, 14 and 1 are related to the rare early onset forms of AD while the epsilon 4 allele of the apolipoprotein E (APOE) gene (on chromosome 19) is the major susceptibility locus for the most common late onset AD (LOAD). Serotonin (5-hydroxytryptamine or 5-HT) is a key neurotransmitter implicated in the control of mood, sleep, appetite and a variety of traits and behaviors. Recently, a polymorphism in the transcriptional control region upstream of the 5-HT transporter (5-HTT) gene has been studied in several psychiatric diseases and personality traits. It has been demonstrated that the short variant(s) of this 5-HTT gene-linked polymorphic region (5-HTTLPR) is associated with a different transcriptional efficiency of the 5-HTT gene promoter resulting in decreased 5-HTT expression and 5-HT uptake in lymphocytes. An increased frequency of this 5-HTTLPR short variant polymorphism in LOAD was recently reported. In addition, another common polymorphic variation in the 5-HT2A and 5-HT2C serotonin receptor genes previously analyzed in schizophrenic patients was associated with auditory and visual hallucinations in AD. These observations suggest that the involvement of the serotonin pathway might provide an explanation for some aspects of the affective symptoms commonly observed in AD patients. In summary, research on genetic polymorphisms related to AD and involved in receptors, transporter proteins and the enzymatic machinery of serotonin might enhance our understanding of this devastating neurodegenerative disorder.

  5. The effect of adding group-based counselling to individual lifestyle counselling on changes in dietary intake. The Inter99 study – a randomized controlled trial

    Directory of Open Access Journals (Sweden)

    Smith Lisa

    2008-11-01

    Full Text Available Abstract Background Few studies have investigated the specific effect of single intervention components in randomized controlled trials. The purpose was to investigate the effect of adding group-based diet and exercise counselling to individual life-style counselling on long-term changes in dietary habits. Methods The study was a randomized controlled intervention study. From a general Danish population, aged 30 to 60 years (n = 61,301, two random sample were drawn (group A, n = 11,708; group B, n = 1,308. Subjects were invited for a health screening program. Participation rate was 52.5%. All participants received individual life-style counselling. Individuals at high risk of ischemic heart disease in group A were furthermore offered group-based life-style counselling. The intervention was repeated for high-risk individuals after one and three years. At five-year follow-up all participants were invited for a health examination. High risk individuals were included in this study (n = 2 356 and changes in dietary intake were analyzed using multilevel linear regression analyses. Results At one-year follow-up group A had significantly increased the unsaturated/saturated fat ratio compared to group B and in men a significantly greater decrease in saturated fat intake was found in group A compared to group B (net change: -1.13 E%; P = 0.003. No differences were found between group A and B at three-year follow-up. At five-year follow-up group A had significantly increased the unsaturated/saturated fat ratio (net change: 0.09; P = 0.01 and the fish intake compared to group B (net change: 5.4 g/day; P = 0.05. Further, in men a non-significant tendency of a greater decrease was found at five year follow-up in group A compared to group B (net change: -0.68 E%; P = 0.10. The intake of fibre and vegetables increased in both groups, however, no significant difference was found between the groups. No differences between groups were found for saturated fat

  6. Higher spin holography and the AdS string sigma model

    Science.gov (United States)

    Polyakov, Dimitri

    2013-05-01

    We analyse the cubic spin-3 interaction in AdS space using the higher spin extension of the string-theoretic sigma-model constructed in our previous work, whose low energy limit is described by the AdS vacuum solution. We find that, in the leading order of the cosmological constant, the spin-3 correlator on the AdS4 string theory side reproduces the structure of the three-point function of composite operators, quadratic in free fields, in the dual d = 3 vector model. The cancellation of holography violating terms in d = 3 is related to the value of the Liouville background charge in d = 4. This article is part of a special issue of Journal of Physics A: Mathematical and Theoretical devoted to ‘Higher spin theories and holography’.

  7. Supersymmetry of AdS and flat IIB backgrounds

    Science.gov (United States)

    Beck, S.; Gutowski, J.; Papadopoulos, G.

    2015-02-01

    We present a systematic description of all warped AdS n × w M 10- n and IIB backgrounds and identify the a priori number of supersymmetries N preserved by these solutions. In particular, we find that the AdS n backgrounds preserve for n ≤ 4 and for 4 < n ≤ 6 supersymmetries and for suitably restricted. In addition under some assumptions required for the applicability of the maximum principle, we demonstrate that the Killing spinors of AdS n backgrounds can be identified with the zero modes of Dirac-like operators on M 10- n establishing a new class of Lichnerowicz type theorems. Furthermore, we adapt some of these results to backgrounds with fluxes by taking the AdS radius to infinity. We find that these backgrounds preserve for 2 < n ≤ 4 and for 4 < n ≤ 7 supersymmetries. We also demonstrate that the Killing spinors of AdS n × w M 10- n do not factorize into Killing spinors on AdS n and Killing spinors on M 10- n .

  8. Risk for self-reported anorexia or bulimia nervosa based on drive for thinness and negative affect clusters/dimensions during adolescence: A three-year prospective study of the TChAD cohort

    Science.gov (United States)

    Peñas-Lledó, Eva; Bulik, Cynthia M.; Lichtenstein, Paul; Larsson, Henrik; Baker, Jessica H.

    2015-01-01

    Objective The present study explored the cross-sectional and predictive effect of drive for thinness and/or negative affect scores on the development of self-reported anorexia nervosa (AN) and bulimia nervosa (BN). Method K-means were used to cluster the Eating Disorder Inventory-Drive for Thinness (DT) and Child Behavior Checklist Anxious/Depressed (A/D) scores from 615 unrelated female twins at age 16–17. Logistic regressions were used to assess the effect of these clusters on self-reported eating disorder diagnosis at ages 16–17 (n=565) and 19–20 (n=451). Results DT and A/D scores were grouped into four clusters: Mild (scores lower than 90th percentile on both scales), DT (higher scores only on DT), A/D (higher scores only on A/D), and DT-A/D (higher scores on both the DT and A/D scales). DT and DT-A/D clusters at age 16–17 were associated cross-sectionally with AN and both cross-sectionally and longitudinally with BN. The DT-A/D cluster had the highest prevalence of AN at follow-up compared with all other clusters. Similarly, an interaction was observed between DT and A/D that predicted risk for AN. Discussion Having elevated DT and A/D scores may increase risk for eating disorder symptomatology above and beyond a high score on either alone. Findings suggest that cluster modeling based on DT and A/D may be useful to inform novel and useful intervention strategies for AN and BN in adolescents. PMID:26013185

  9. Study on address allocation in mobile Ad hoc networks%移动自组网地址配置问题的研究

    Institute of Scientific and Technical Information of China (English)

    薛咏

    2006-01-01

    MANET(Mobile Ad hoc Network)中没有一个永久的中心机构,其网络拓扑结构不断变化,所以必须有一种能够对网络主机地址动态自配置和管理的协议.给出了在MANET中动态地址自配置与管理的方法,不同方案的特点及适应情况,最后对目前Ad hoc网络地址配置研究进行总结和展望.

  10. Turbulent strings in AdS/CFT

    CERN Document Server

    Ishii, Takaaki

    2015-01-01

    We study nonlinear dynamics of the flux tube between an external quark-antiquark pair in $\\mathcal{N}=4$ super Yang-Mills theory using the AdS/CFT duality. In the gravity side, the flux tube is realized by a fundamental string whose endpoints are attached to the AdS boundary. We perturb the endpoints in various ways and numerically compute the time evolution of the nonlinearly oscillating string. As a result, cusps can form on the string, accompanied by weak turbulence and power law behavior in the energy spectrum. When cusps traveling on the string reach the boundary, we observe the divergence of the force between the quark and antiquark. Minimal amplitude of the perturbation below which cusps do not form is also investigated. No cusp formation is found when the string moves in all four AdS space directions, and in this case an inverse energy cascade follows a direct cascade.

  11. The Impact of Ad Characteristics on Adolescents’ Attitudes Towards Antismoking Ads

    Directory of Open Access Journals (Sweden)

    Domen Bajde

    2008-03-01

    Full Text Available Smoking exerts a considerable burden not only on those who smoke but just as well on society at large. In response, governments and institutions often resort to advertising which aims to discourage smoking. Unfortunately, our knowledge of the workings of antismoking advertising is detrimentally limited. In particular, the literature delving into the impact of antismoking ad characteristics (e. g., ad content, valence, intensity on the overall effectiveness of antismoking advertising is scarce and contradictory. This empirical study aims to enhance the knowledge of antismoking advertising by presenting results of the survey involving Slovene adolescents. The adolescents were first exposed to advertisements of different antismoking ad contents (for the purpose of this study the term ‘ad content’ refers to types of appeals used in antismoking advertising, ad valence and intensity, and later invited to respond to a number of questions measuring their attitudes toward the ads, their attitudes toward smoking, their intentions to smoke, etc. The results indicate that while the different intensity and valence of ads produce varying attitudes toward the ads, we could not confirm these differences based on ad content. Also, we found that adolescent smokers respond to antismoking ads differently than do their nonsmoking peers. Our findings offer several important implications for antismoking advertisers and the research community interested in the workings of antismoking advertising.

  12. Inflation in AdS/CFT

    Energy Technology Data Exchange (ETDEWEB)

    Freivogel, Ben; /Stanford U., Phys. Dept. /LBL, Berkeley; Hubeny, Veronika E.; /LBL, Berkeley /Durham U., Dept. of Math.; Maloney, Alexander; /Stanford U., Phys. Dept.; Myers, Rob; /Perimeter Inst. Theor. Phys. /Waterloo U.; Rangamani, Mukund; /LBL, Berkeley /Durham U., Dept. of Math.; Shenker, Stephen; /Stanford U., Phys. Dept.

    2005-10-07

    We study the realization of inflation within the AdS/CFT correspondence. We assume the existence of a string landscape containing at least one stable AdS vacuum and a (nearby) metastable de Sitter state. Standard arguments imply that the bulk physics in the vicinity of the AdS minimum is described by a boundary CFT. We argue that large enough bubbles of the dS phase, including those able to inflate, are described by mixed states in the CFT. Inflating degrees of freedom are traced over and do not appear explicitly in the boundary description. They nevertheless leave a distinct imprint on the mixed state. Analytic continuation allows us, in principle, to recover a large amount of nonperturbatively defined information about the inflating regime. Our work also shows that no scattering process can create an inflating region, even by quantum tunneling, since a pure state can never evolve into a mixed state under unitary evolution.We study the realization of inflation within the AdS/CFT correspondence. We assume the existence of a string landscape containing at least one stable AdS vacuum and a (nearby) metastable de Sitter state. Standard arguments imply that the bulk physics in the vicinity of the AdS minimum is described by a boundary CFT. We argue that large enough bubbles of the dS phase, including those able to inflate, are described by mixed states in the CFT. Inflating degrees of freedom are traced over and do not appear explicitly in the boundary description. They nevertheless leave a distinct imprint on the mixed state. Analytic continuation allows us, in principle, to recover a large amount of nonperturbatively defined information about the inflating regime. Our work also shows that no scattering process can create an inflating region, even by quantum tunneling, since a pure state can never evolve into a mixed state under unitary evolution.

  13. Stress-induced comenditic trachyte effusion triggered by trachybasalt intrusion : multidisciplinary study of the AD 1761 eruption at Terceira Island (Azores)

    NARCIS (Netherlands)

    Pimentel, A.; Zanon, V.; de Groot, Lennart; Hipólito, A.; Di Chiara, A.; Self, S.

    2016-01-01

    The AD 1761 eruption on Terceira was the only historical subaerial event on the island and one of the last recorded in the Azores. The eruption occurred along the fissure zone that crosses the island and produced a trachybasalt lava flow and scoria cones. Small comenditic trachyte lava domes (known

  14. Metabolomic study of plasma from female mink (Neovison vison) with low and high residual feed intake during restrictive and ad libitum feeding

    DEFF Research Database (Denmark)

    Hedemann, Mette Skou; Damgaard, Birthe Marie

    2012-01-01

    was high during restrictive feeding, e.g. betaine, carnitine, and creatine. During ad libitum feeding the plasma level of metabolites that can be characterized as biomarkers of meat intake (creatinine, carnosine, 1- and 3 methylhistidine) was high. The plasma level of lysophosphatidylcholine species...

  15. Complexity Growth for AdS Black Holes

    CERN Document Server

    Cai, Rong-Gen; Wang, Shao-Jiang; Yang, Run-Qiu; Peng, Rong-Hui

    2016-01-01

    We further investigate the Complexity-Action (CA) duality conjecture for stationary anti de-Sitter (AdS) black holes and derive some exact results for the growth rate of action within Wheeler-DeWitt (WDW) patch at late time approximation, which is dual to the growth rate of quantum complexity of holographic state. Based on the results from the general $D$-dimensional Reissner-Nordstr\\"{o}m (RN)-AdS black hole, rotating/charged Ba\\~{n}ados-Teitelboim-Zanelli (BTZ) black hole, Kerr-AdS black hole and charged Gauss-Bonnet-AdS black hole, we present a new complexity bound but leave unchanged the conjecture that the stationary AdS black hole in Einstein gravity is the fastest computer in nature.

  16. Mediated relations: New methods to study online social capital

    NARCIS (Netherlands)

    Vergeer, M.R.M.; Lim, Y.S.; Park, H.W.

    2011-01-01

    The Web has expanded the research agenda for communication scholars to study social capital. In this field of Internet studies, new indicators of social behavior and social relations have surfaced to describe and understand how social capital develops online and what the consequences are for social

  17. Ethical issues related to biomonitoring studies on children

    DEFF Research Database (Denmark)

    Pedersen, Marie; Merlo, Domenico Franco; Knudsen, Lisbeth E.

    2007-01-01

    -off and the recruitments. In the initial phase of planning a biomonitoring study consideration of communication of results including risk and means of risk prevention should be made. Ethical considerations regarding the study protocol should take into account (a) justification of biological sampling related...

  18. The ADS All Sky Survey

    Science.gov (United States)

    Goodman, Alyssa

    We will create the first interactive sky map of astronomers' understanding of the Universe over time. We will accomplish this goal by turning the NASA Astrophysics Data System (ADS), widely known for its unrivaled value as a literature resource, into a data resource. GIS and GPS systems have made it commonplace to see and explore information about goings-on on Earth in the context of maps and timelines. Our proposal shows an example of a program that lets a user explore which countries have been mentioned in the New York Times, on what dates, and in what kinds of articles. By analogy, the goal of our project is to enable this kind of exploration-on the sky-for the full corpus of astrophysical literature available through ADS. Our group's expertise and collaborations uniquely position us to create this interactive sky map of the literature, which we call the "ADS All-Sky Survey." To create this survey, here are the principal steps we need to follow. First, by analogy to "geotagging," we will "astrotag," the ADS literature. Many "astrotags" effectively already exist, thanks to curation efforts at both CDS and NED. These efforts have created links to "source" positions on the sky associated with each of the millions of articles in the ADS. Our collaboration with ADS and CDS will let us automatically extract astrotags for all existing and future ADS holdings. The new ADS Labs, which our group helps to develop, includes the ability for researchers to filter article search results using a variety of "facets" (e.g. sources, keywords, authors, observatories, etc.). Using only extracted astrotags and facets, we can create functionality like what is described in the Times example above: we can offer a map of the density of positions' "mentions" on the sky, filterable by the properties of those mentions. Using this map, researchers will be able to interactively, visually, discover what regions have been studied for what reasons, at what times, and by whom. Second, where

  19. Respiratory gated PET/CT in a European multicentre retrospective study: added diagnostic value in detection and characterization of lung lesions

    Energy Technology Data Exchange (ETDEWEB)

    Guerra, Luca; Elisei, Federica [San Gerardo Hospital, Nuclear Medicine, Monza (Italy); De Ponti, Elena [San Gerardo Hospital, Medical Physics, Monza (Italy); Bettinardi, Valentino; Picchio, Maria [San Raffaele Scientific Institute, Nuclear Medicine, Milan (Italy); National Research Council, Institute for Bioimaging and Molecular Physiology, Milan (Italy); Landoni, Claudio [San Raffaele Scientific Institute, Nuclear Medicine, Milan (Italy); University of Milano-Bicocca, Milan (Italy); Gilardi, Maria Carla [San Raffaele Scientific Institute, Nuclear Medicine, Milan (Italy); National Research Council, Institute for Bioimaging and Molecular Physiology, Milan (Italy); University of Milano-Bicocca, Tecnomed Foundation, Milan (Italy); Versari, Annibale [Scientific Institute Santa Maria Nuova Hospital, Nuclear Medicine, Reggio Emilia (Italy); Fioroni, Federica [Scientific Institute Santa Maria Nuova Hospital, Medical Physics, Reggio Emilia (Italy); Dziuk, Miroslaw [Masovian PET-CT Centre, Department of Nuclear Medicine, Military Institute of Medicine, Warsaw (Poland); Koza, Magdalena [Masovian PET-CT Centre, Euromedic Diagnostic, Warsaw (Poland); Ahond-Vionnet, Renee; Collin, Bertrand [Hopital Pierre Beregovoy, Service de Medecine Nucleaire, Nevers (France); Messa, Cristina [San Gerardo Hospital, Nuclear Medicine, Monza (Italy); National Research Council, Institute for Bioimaging and Molecular Physiology, Milan (Italy); University of Milano-Bicocca, Tecnomed Foundation, Milan (Italy)

    2012-09-15

    The aim of our work is to evaluate the added diagnostic value of respiratory gated (4-D) positron emission tomography/computed tomography (PET/CT) in lung lesion detection/characterization in a large patient population of a multicentre retrospective study. The data of 155 patients (89 men, 66 women, mean age 63.9 {+-} 11.1 years) from 5 European centres and submitted to standard (3-D) and 4-D PET/CT were retrospectively analysed. Overall, 206 lung lesions were considered for the analysis (mean {+-} SD lesions dimension 14.7 {+-} 11.8 mm). Maximum standardized uptake values (SUV{sub max}) and lesion detectability were assessed for both 3-D and 4-D PET/CT studies; 3-D and 4-D PET/CT findings were compared to clinical follow-up as standard reference. Mean {+-} SD 3-D and 4-D SUV{sub max} values were 5.2 {+-} 5.1 and 6.8 {+-} 6.1 (p < 0.0001), respectively, with an average percentage increase of 30.8 %. In 3-D PET/CT, 86 of 206 (41.7 %) lesions were considered positive, 70 of 206 (34 %) negative and 50 of 206 (24.3 %) equivocal, while in 4-D PET/CT 117 of 206 (56.8 %) lesions were defined as positive, 80 of 206 (38.8 %) negative and 9 of 206 (4.4 %) equivocal. In 34 of 50 (68 %) 3-D equivocal lesions follow-up data were available and the presence of malignancy was confirmed in 21 of 34 (61.8 %) lesions, while in 13 of 34 (38.2 %) was excluded. In 31 of these 34 controlled lesions, 20 of 34 (58.8 %) and 11 of 34 (32.4 %) were correctly classified by 4-D PET/CT as positive and negative, respectively; 3 of 34 (8.8 %) remained equivocal. With equivocal lesions classified as positive, the overall accuracy of 3-D and 4-D was 85.7 and 92.8 %, respectively, while the same figures were 80.5 and 94.2 % when equivocal lesions were classified as negative. The respiratory gated PET/CT technique is a valuable clinical tool in diagnosing lung lesions, improving quantification and confidence in reporting, reducing 3-D undetermined findings and increasing the overall accuracy in lung

  20. A Chemopreventive Trial to Study the Effects of High Tea Consumption on Smoking-Related Oxidative Stress

    Science.gov (United States)

    2006-02-01

    479.76 583.65 425.47 448.57 n 127 43 42 42 f) Determination of each subiect’s baseline history of smoking, diet and tea intake, plasma catechins ...AD Award Number: DAMD17-03-1-0053 TITLE: A Chemopreventive Trial to Study the Effects of High Tea Consumption on Smoking-Related Oxidative Stress...2006 4. TITLE AND SUBTITLE 5a. CONTRACT NUMBER A Chemopreventive Trial to Study the Effects of High Tea Consumption on Smoking- 5b. GRANT NUMBER Related

  1. AD Consolidation for operation beyond 2010

    CERN Document Server

    Eriksson, T

    2008-01-01

    The Antiproton Decelerator (AD), which started up for physics in 2000 and today supplies low-energy antiprotons to the ATRAP, ALPHA, ASACUSA and ACE experiments is based on the ACOL machine from which it still retains most of the components. ACOL construction was completed in 1986 at a total cost of approximately 80 MCHF (excluding infrastructure) which today would correspond to a value of around 160 MCHF. During recent years, a reduction of maintenance and modernisation has been unavoidable due to budgetary restraints. In order to identify the resources needed for continued AD operation beyond 2010 with a reasonably low risk of failures and to avoid increasing maintenance and repair costs, a study has been conducted involving groups from the AB, AT and TS departments. Analysis of breakdown risks, identification of items and costs for consolidation has been done as well as a risk score classification. To be noted is the relatively modest cost of the proposed items in view of the value of the facility and in c...

  2. POSSIBLE CHROMOSPHERIC ACTIVITY CYCLES IN AD LEO

    Energy Technology Data Exchange (ETDEWEB)

    Buccino, Andrea P.; Petrucci, Romina; Mauas, Pablo J. D. [Instituto de Astronomía y Física del Espacio (CONICET-UBA), C.C. 67 Sucursal 28, C1428EHA-Buenos Aires (Argentina); Jofré, Emiliano [Observatorio Astronómico de Córdoba, Córdoba (Argentina)

    2014-01-20

    AD Leo (GJ 388) is an active dM3 flare star that has been extensively observed both in the quiescent and flaring states. Since this active star is near the fully convective boundary, studying its long-term chromospheric activity in detail could be an appreciable contribution to dynamo theory. Here, using the Lomb-Scargle periodogram, we analyze the Ca II K line-core fluxes derived from CASLEO spectra obtained between 2001 and 2013 and the V magnitude from the ASAS database between 2004 and 2010. From both of these totally independent time series, we obtain a possible activity cycle with a period of approximately seven years and a less significant shorter cycle of approximately two years. A tentative interpretation is that a dynamo operating near the surface could be generating the longer cycle, while a second dynamo operating in the deep convection zone could be responsible for the shorter one. Based on the long duration of our observing program at CASLEO and the fact that we observe different spectral features simultaneously, we also analyze the relation between simultaneous measurements of the Na I index (R{sub D}{sup ′}), Hα, and Ca II K fluxes at different activity levels of AD Leo, including flares.

  3. O PROCESSO AD(EOD - UM NOVO CONCEITO

    Directory of Open Access Journals (Sweden)

    Cristiane Pedrazzi

    2009-01-01

    Full Text Available In this study, cooking of the wood had been investigated until kappa numbers 17 and 14 for a process kinetically modified, elimination of oxygen delignification from the fiber line, and application of AD(EOD and AD(POD techniques for pulp of kappa 17 and AD(EOD and DHT(EPODP for pulp of kappa 14 for the bleaching at 90% ISO. As references, cookings had been carried out until kappa number 17 and 14, oxygen delignification in simple stage and conventional bleaching with sequences A/D(EOD, A/D(EPOD, A/D(EODP and A/D(EPODP for the kappa number 17 pulp and oxygen delignification in simple stage and conventional bleaching sequence DHT(EPODP for pulp of kappa 14. For the pulp of kappa 17, one concluded that processes AD(EOD and AD(POD produced pulp of brightness 90% ISO with good viscosity and brightness stability, using TAC's (totally active chloro relatively low, and it's not necessary the oxygen delignification. Amongst these two processes, the first one revealed to be more attractive to reach the level of 90% ISO brightness. However, comparatively to the reference processes, with oxygen delignification, for example O-A/D(EPODP, process AD(EOD results in increase of the operational cost of the order of US$7-8/odt, including wood and reagents. For the kappa number 14 pulp, process AD(EOD also revealed to be attractive, but the sequence DHT(EPODP was the one that used lower TAC's; however, when compared with the reference (O-DHT(EPODP, it resulted in an increase of operational cost of the order of US$5/odt. Therefore, it can be concluded that the alternative process, without the deslignification with oxygen, is viable only for pulps of lower kappa number.

  4. Personality-Related Determinants of Subtle Cognitive Decline in Old Age: A Population-Based Study

    Directory of Open Access Journals (Sweden)

    Cristelle Rodriguez

    2016-04-01

    Full Text Available Background/Aims: Recent studies of cases with mild cognitive impairment (MCI suggested that besides Alzheimer disease (AD-related biomarkers, some personality dimensions are associated with progression to AD. To date, there are no studies addressing the psychological determinants of subtle cognitive decline in healthy elderly controls. Methods: 488 community-dwelling healthy controls were assessed with a detailed neuropsychological battery at baseline and an 18-month follow-up. Personality factors and facets were investigated at baseline using the NEO-Personality Inventory-Revised (NEO-PI-R. Upon follow-up, there were 264 stable controls (sCON and 224 deteriorating controls (dCON. Their personality data were compared to those of the 102 MCI cases using one-way analysis of variance and logistic regression models. Results: Significantly higher scores of Openness factor (as well as Aesthetics, Ideas and Values facets were found in sCON than in both dCON and MCI cases. The three groups did not differ in the other NEO-PI-R factor and facet scores. Openess factor (and the same facets was associated with cognitive preservation in healthy controls (OR: 0.72, 95% CI: 0.59, 0.87. Lower scores in the same factor and facets conferred higher risk to have MCI (OR: 0.61, 95% CI: 0.46, 0.79. Conclusion: Higher openness to new experiences and thoughts may be a protective factor against early cognitive decline in brain aging.

  5. On the Thermodynamic Geometry and Critical Phenomena of AdS Black Holes

    CERN Document Server

    Sahay, Anurag; Sengupta, Gautam

    2010-01-01

    In this paper, we study various aspects of the equilibrium thermodynamic state space geometry of AdS black holes. We first examine the Reissner-Nordstrom-AdS (RN-AdS) and the Kerr-AdS black holes. In this context, the state space scalar curvature of these black holes are analysed in various regions of their thermodynamic parameter space. This provides important new insights into the structure and significance of the scalar curvature. We further investigate critical phenomena, and the behaviour of the scalar curvature near criticality, for KN-AdS black holes in two mixed ensembles, introduced and elucidated in our earlier work arXiv:1002.2538 [hep-th]. The critical exponents are identical to those in the RN-AdS and Kerr-AdS cases in the canonical ensemble. This suggests an universality in the scaling behaviour near critical points of AdS black holes. Our results further highlight qualitative differences in the thermodynamic state space geometry for electric charge and angular momentum fluctuations of these.

  6. Different views of AEGIS / AD-6 Experiment (AD facility) AD-6

    CERN Multimedia

    Maximilien Brice

    2012-01-01

    Different views of AEGIS / AD-6 Experiment (AD facility) in July of 2012. The visible parts are the positron accumulator (blue structures on top of of the antiproton extraction line) and the 5T magnet which traps the antiprotons.

  7. Study on relative orbital configuration in satellite formation flying

    Institute of Scientific and Technical Information of China (English)

    Junfeng Li; Xin Meng; Yunfeng Gao; Xiang Li

    2005-01-01

    In this paper, the relative orbital configurations of satellites in formation flying with non-perturbation and J2 perturbation are studied, and an orbital elements method is proposed to obtain the relative orbital configurations of satellites in formation. Firstly, under the condition of nonperturbation, we obtain many shapes of relative orbital configurations when the semi-major axes of satellites are equal.These shapes can be lines, ellipses or distorted closed curves.Secondly, on the basis of the analysis of J2 effect on relative orbital configurations, we find out that J2 effect can induce two kinds of changes of relative orbital configurations. They are distortion and drifting, respectively. In addition, when J2perturbation is concerned, we also find that the semi-major axes of the leading and following satellites should not be the same exactly in order to decrease the J2 effect. The relationship of relative orbital elements and J2 effect is obtained through simulations. Finally, the minimum relation perturbation conditions are established in order to reduce the influence of the J2 effect. The results show that the minimum relation perturbation conditions can reduce the J2 effect significantly when the orbital element differences are small enough, and they can become rules for the design of satellite formation flying.

  8. Alteration of mTOR signaling occurs early in the progression of Alzheimer disease (AD): analysis of brain from subjects with pre-clinical AD, amnestic mild cognitive impairment and late-stage AD.

    Science.gov (United States)

    Tramutola, Antonella; Triplett, Judy C; Di Domenico, Fabio; Niedowicz, Dana M; Murphy, Michael P; Coccia, Raffaella; Perluigi, Marzia; Butterfield, D Allan

    2015-06-01

    The clinical symptoms of Alzheimer disease (AD) include a gradual memory loss and subsequent dementia, and neuropathological deposition of senile plaques and neurofibrillary tangles. At the molecular level, AD subjects present overt amyloid β (Aβ) production and tau hyperphosphorylation. Aβ species have been proposed to overactivate the phosphoinositide3-kinase (PI3K)/Akt/mammalian target of rapamycin (mTOR) axis, which plays a central role in proteostasis. The current study investigated the status of the PI3K/Akt/mTOR pathway in post-mortem tissue from the inferior parietal lobule (IPL) at three different stages of AD: late AD, amnestic mild cognitive impairment (MCI) and pre-clinical AD (PCAD). Our findings suggest that the alteration of mTOR signaling and autophagy occurs at early stages of AD. We found a significant increase in Aβ (1-42) levels, associated with reduction in autophagy (Beclin-1 and LC-3) observed in PCAD, MCI, and AD subjects. Related to the autophagy impairment, we found a hyperactivation of PI3K/Akt/mTOR pathway in IPL of MCI and AD subjects, but not in PCAD, along with a significant decrease in phosphatase and tensin homolog. An increase in two mTOR downstream targets, p70S6K and 4EBP1, occurred in AD and MCI subjects. Both AD and MCI subjects showed increased, insulin receptor substrate 1, a candidate biomarker of brain insulin resistance, and GSK-3β, a kinase targeting tau phosphorylation. Nevertheless, tau phosphorylation was increased in the clinical groups. The results hint at a link between Aβ and the PI3K/Akt/mTOR axis and provide further insights into the relationship between AD pathology and insulin resistance. In addition, we speculate that the alteration of mTOR signaling in the IPL of AD and MCI subjects, but not in PCAD, is due to the lack of substantial increase in oxidative stress. The figure represents the three different stages of Alzheimer Disease: Preclinical Alzheimer Disease (PCAD), Mild cognitive impairment (MCI

  9. A randomized study of oral nutritional support versus ad lib nutritional intake during chemotherapy for advanced colorectal and non-small-cell lung cancer.

    Science.gov (United States)

    Evans, W K; Nixon, D W; Daly, J M; Ellenberg, S S; Gardner, L; Wolfe, E; Shepherd, F A; Feld, R; Gralla, R; Fine, S

    1987-01-01

    One hundred ninety-two patients with previously untreated metastatic cancer (102 non-small-cell lung cancer [NSCLC]; 90 colorectal cancer) were randomized to receive either ad lib nutritional intake (control group) or specific nutritional intervention during a 12-week study period when chemotherapy was administered. Those patients randomized to nutritional interventions were counselled to take oral nutrients with caloric intake equal to 1.7 to 1.95 times their basal energy expenditure, depending on their pretreatment nutritional status ("standard" group). An augmented group was counselled to have a caloric intake equivalent to that of the standard group but with 25% of calories provided as protein and additional supplements of zinc and magnesium. Counselling increased caloric intake in both tumor types but reduced weight loss in the short term only for lung cancer patients. Ninety-three NSCLC patients were evaluable for tumor response to vindesine and cisplatin. Overall, only 20.4% of the patients responded, and there were no significant differences in response rates, median time to progression, or overall duration of survival between the nutrition intervention groups and the control group. The tumor response rate to time-sequenced 5-fluorouracil (5-FU) and methotrexate in the 81 evaluable patients with colorectal cancer was only 14.8%, and no significant differences in tumor response rates were noted between the three groups. Furthermore, the median time to progression and overall duration of survival were not different for the control, standard, and augmented groups. Nutritional interventions using dietary counselling had no impact on the percent of planned chemotherapy dose administered, the degree of toxicity experienced by patients, or the frequency of treatment delays. A multivariate prognostic factor analysis demonstrated that for lung cancer, the percent of weight loss, serum albumin concentration, and presence of liver metastases were significant (P less

  10. Employment and taxes in Latin America: An empirical study of the effects of payroll, corporate income and value-added taxes on labor outcomes

    Directory of Open Access Journals (Sweden)

    Eduardo Lora

    2016-01-01

    Full Text Available This paper empirically explores the effects of payroll taxes, value-added taxes and corporate income taxes on a variety of labor market outcomes such as participation, employment, informality, and wages. The results are based on nationallevel data of labor variables for 15 Latin American countries, and indicate that the effects of each tax are markedly different and may depend on several aspects of labor and tax institutions. Payroll taxes reduce employment and increase labor costs when their benefits are not valued by workers, but otherwise may increase labor participation and not raise labor costs. Value-added taxes increase informality and reduce skilled labor demand. In contrast, corporate income taxes may help reduce informality, especially among low education workers, but when tax enforcement capabilities are strong they may reduce labor participation and employment of medium- and high-education workers.

  11. Sports training influencing antioxidation ability and its relation with AD precaution%运动训练对抗氧化能力的影响与预防AD的关系

    Institute of Scientific and Technical Information of China (English)

    范庆磊; 徐波

    2011-01-01

    The sports training can improve the activity of SOD so as to improve the antioxidation ability and free radical removal ability. The sports training also can decrease the MDA in the animal's brain, improve the memory and have the AD precaution. The paper summerises the domestic and overseas researches about the relation among sports training, free radicals and memory and proposes that sports training can improve the ability to remove the free radicals by increasing the antioxidation ability in the brain.%运动训练能够增强动物脑内超氧化物歧化酶(SOD)的活性,从而增强机体的抗氧化能力和清除自由基能力,同时降低丙二醛(MDA)在动物脑内的含量,并且使动物的学习记忆能力得到一定的改善,预防阿尔茨海默病。综述国内外有关运动训练、自由基与学习记忆的研究报道,分析并推测运动可能通过提高机体脑内抗氧化能力以增强机体对自由基的清除能力,从而改善机体的学习记忆能力,预防阿尔茨海默病。

  12. On thermodynamics of AdS black holes in M-theory

    Energy Technology Data Exchange (ETDEWEB)

    Belhaj, A. [Universite Sultan Moulay Slimane, Departement de Physique, LIRST, Faculte Polydisciplinaire, Beni Mellal (Morocco); Cadi Ayyad University, High Energy Physics and Astrophysics Laboratory, FSSM, Marrakesh (Morocco); Chabab, M.; Masmar, K. [Cadi Ayyad University, High Energy Physics and Astrophysics Laboratory, FSSM, Marrakesh (Morocco); El Moumni, H. [Cadi Ayyad University, High Energy Physics and Astrophysics Laboratory, FSSM, Marrakesh (Morocco); Universite Ibn Zohr, Departement de Physique, Faculte des Sciences, Agadir (Morocco); Sedra, M.B. [Universite Ibn Tofail, Departement de Physique, LASIMO, Faculte des Sciences, Kenitra (Morocco)

    2016-02-15

    Motivated by recent work on asymptotically AdS{sub 4} black holes in M-theory, we investigate the thermodynamics and thermodynamical geometry of AdS black holes from M2- and M5-branes. Concretely, we consider AdS black holes in AdS{sub p+2} x S{sup 11-p-2}, where p = 2,5 by interpreting the number of M2- (and M5-branes) as a thermodynamical variable. More precisely, we study the corresponding phase transition to examine their stabilities by calculating and discussing various thermodynamical quantities including the chemical potential. Then we compute the thermodynamical curvatures from the Quevedo metric for M2- and M5-branes geometries to reconsider the stability of such black holes. The Quevedo metric singularities recover similar stability results provided by the phase-transition program. It has been shown that similar behaviors are also present in the limit of large N. (orig.)

  13. Study on Generation-adding Technology for Duanye No.13 Radish%短叶13号萝卜加代技术研究

    Institute of Scientific and Technical Information of China (English)

    骆海波; 李世升; 李德超; 贺从安

    2014-01-01

    In the paper, we treated radish dry seeds, germinated seeds and seedlings in low temperature respectively, in order to screen out suitable generation-adding material for Duanye No.13 radish and find out faster, more convenient generation-adding method for radish. The results showed that, compared with the other two materials, dry radish seeds could not flower after the cold temperature treatment. After being treated in low temperature, germinated radish seeds had higher flowering ratio and it was easier and more simple to take germinated seeds as generation-adding materials for radish. As a result, taking germinated seeds as generation-adding materials for radish could shorten the breeding process and improve the breeding efficiency of radish.%通过低温处理萝卜干种子、萌动种子及幼苗,以期从中筛选出更适合短叶13号萝卜加代研究的材料,寻找更快、更方便的萝卜加代方法。试验结果表明,相比其他两类材料,萝卜干种子不易完成春化而开花;而在萝卜萌动种子及萝卜幼苗两类材料中,前者加代操作相对简便且低温处理定植后开花比例较高。因此,将萌动种子作为萝卜加代材料可缩短育种进程、提高育种效率。

  14. Detailed ultraviolet asymptotics for AdS scalar field perturbations

    CERN Document Server

    Evnin, Oleg

    2016-01-01

    We present a range of methods suitable for accurate evaluation of the leading asymptotics for integrals of products of Jacobi polynomials in limits when the degrees of some or all polynomials inside the integral become large. The structures in question have recently emerged in the context of effective descriptions of small amplitude perturbations in anti-de Sitter (AdS) spacetime. The limit of high degree polynomials corresponds in this situation to effective interactions involving extreme short-wavelength modes, whose dynamics is crucial for the turbulent instabilities that determine the ultimate fate of small AdS perturbations. We explicitly apply the relevant asymptotic techniques to the case of a self-interacting probe scalar field in AdS and extract a detailed form of the leading large degree behavior, including closed form analytic expressions for the numerical coefficients appearing in the asymptotics.

  15. Microstates at the boundary of AdS

    CERN Document Server

    Mathur, Samir D

    2011-01-01

    The bound states of the D1D5 brane system have a known gravitational description: flat asymptotics, an anti-de Sitter region, and a 'cap' ending the AdS region. We construct perturbations that correspond to the action of chiral algebra generators on Ramond ground states of D1D5 branes. Abstract arguments in the literature suggest that the perturbation should be pure gauge in the AdS region; our perturbation indeed has this structure, with the nontrivial deformation of the geometry occurring at the 'neck' between the AdS region and asymptotic infinity. This 'non-gauge' deformation is needed to provide the nonzero energy and momentum carried by the perturbation. We also suggest implications this structure may have for the majority of microstates which live at the cap.

  16. The neuromechanism underlying verbal analogical reasoning of metaphorical relations: an event-related potentials study.

    Science.gov (United States)

    Zhao, Ming; Meng, Huishan; Xu, Zhiyuan; Du, Fenglei; Liu, Tao; Li, Yongxin; Chen, Feiyan

    2011-11-24

    Using event-related potentials (ERPs), this study investigated the neuromechanism underlying verbal analogical reasoning of two different metaphorical relations: attributive metaphor and relational metaphor. The analogical reasoning of attributive metaphor (AM-AR) involves a superficial similarity between analogues, while the analogical reasoning of relational metaphor (RM-AR) requires a structural similarity. Subjects were asked to judge whether one word pair was semantically analogous to another word pair. Results showed that the schema induction stage elicited a greater N400 component at the right anterior scalp for the AM-AR and RM-AR tasks, possibly attributable to semantic processing of metaphorical word pairs. The N400 was then followed by a widely distributed P300 and a late negative component (LNC1) at the left anterior scalp. The P300 was possibly related to the formation of a relational category, while the LNC1 was possibly related to the maintenance of a reasoning cue in working memory. The analogy mapping stage elicited broadly distributed N400 and LNC2, which might indicate the presence of semantic retrieval and analogical transfer. In the answer production stage, all conditions elicited the P2 component due to early stimulus encoding. The largest P2 amplitude was in the RM-AR task. The RM-AR elicited a larger LPC than did the AM-AR, even though the baseline correction was taken as a control for the differential P2 effect. The LPC effect might suggest that relational metaphors involved more integration processing than attributive metaphors.

  17. The generalization of charged AdS black hole specific volume and number density

    Science.gov (United States)

    Wang, Zi-Liang; He, Miao; Fang, Chao; Sun, Dao-Quan; Deng, Jian-Bo

    2017-04-01

    In this paper, by proposing a generalized specific volume, we restudy the P- V criticality of charged AdS black holes in the extended phase space. The results show that most of the previous conclusions can be generalized without change, but the ratio {\\tilde{ρ }}_c should be 3 {\\tilde{α }}/16 in general case. Further research on the thermodynamical phase transition of black hole leads us to a natural interpretation of our assumption, and more black hole properties can be generalized. Finally, we study the number density for charged AdS black hole in higher dimensions, the results show the necessity of our assumption.

  18. 征婚广告的语言特色与社会意义分析%Study on the Linguistic Features and Social Significance of Marriage Ads

    Institute of Scientific and Technical Information of China (English)

    刘晓静; 岳烨晨; 沈烨; 任丹丹; 钱旭

    2014-01-01

    Marriage ads is a type of advertisement by which the seekers advertise himself/herself with a light to find the right one to marry.Owing to its historcic,cultural and economic conditions,the marriage ads in China has become a kind of persusive individual discourse with specific features.Based on the data gathered form some magazines and internet sources,this paper goes into the analysis of the linguistic features and social significance of marriage ads in China to better understand the cututral conotaion behind the prevail-ing custom,folk culture as well as orientation of values.%征婚广告是征婚者通过传媒进行的自我推销以寻求异性伴侣建立婚姻关系的广告形式。中国的征婚广告由于特定的历史、文化和经济背景,形成了一类独具特点的个体劝说语篇。基于期刊、网络等媒体的征婚广告语料分析该类特殊语篇的语言特色及社会意义,以更好地了解其背后所隐藏的时代风尚、民俗文化、价值取向等社会文化内涵。

  19. Profiling value added position in FM

    DEFF Research Database (Denmark)

    Katchamart, Akarapong

    organizations can best add value. Based on comprehensive literature studies and 7 case studies of private and public organisations from Denmark, Holland, Hong Kong and Thailand, the dissertation analyses, how FM organizations can best create added value. From the analyses the following four value added...... - FM organizations influence the business productivities and outcome Each type of value added requires specific conditions and contingencies involved. This research thus offers a visual aid tool, “FM product-process matrix”, to assist practitioners to indicate their existing circumstances and contexts...... the unarticulated notions of added value from FM organization and activities. It will broaden the managerial perception and discussion on FM provision ´s abilities and capabilities. The results are besides the field of FM also of relevance for management of other service industries and functions....

  20. Diffusion and Chaos from near AdS$_2$ horizons

    CERN Document Server

    Blake, Mike

    2016-01-01

    We calculate the thermal diffusivity $D = \\kappa/c_{\\rho}$ and butterfly velocity $v_B$ in holographic models that flow to AdS$_2 \\times R^{d}$ fixed points in the infra-red. We show that both these quantities are governed by the same irrelevant deformation of AdS$_2$ and hence establish a simple relationship between them. When this deformation corresponds to a universal dilaton mode of dimension $\\Delta = 2$ then this relationship is always given by $D = v_B^2/(2 \\pi T)$.

  1. An $xp$ model on $AdS_2$ spacetime

    OpenAIRE

    2012-01-01

    In this paper we formulate the $xp$ model on the AdS$_2$ spacetime. We find that the spectrum of the Hamiltonian has positive and negative eigenvalues, whose absolute values are given by a harmonic oscillator spectrum, which in turn coincides with that of a massive Dirac fermion in AdS$_2$. We extend this result to generic $xp$ models which are shown to be equivalent to a massive Dirac fermion on spacetimes whose metric depend of the $xp$ Hamiltonian. Finally, we construct the generators of t...

  2. Mapping AdS to dS and back

    CERN Document Server

    Di Dato, Adriana

    2014-01-01

    We derive a map between Einstein spaces of positive and negative curvature. Starting from a space of positive curvature with some dimensions compactified on a sphere and analytically continuing the number of compact dimensions, we obtain a space of negative curvature with a compact hyperbolic subspace, and vice versa. Prime examples of such spaces are de Sitter and Anti-de Sitter space, as well as black hole spacetimes with (A)dS asymptotics and perturbed versions thereof, which play an important role in holography. This map extends work done by Caldarelli et.al., who map asymptotically AdS spaces to Ricci-flat ones. A remarkable result is that the boundary of asymptotically AdS spaces is mapped to a brane in the bulk of de Sitter, and perturbations near the AdS boundary are sourced by a stress tensor confined to this brane. We also calculate the Brown-York stress tensor for the perturbed AdS metric, which turns out to be the negative of the stress tensor on the de Sitter brane.

  3. EFFICACY OF ADDING FENTANYL TO LIGNOCAINE – ADRENALINE COMBINATION IN SUPRACLAVICULAR BRACHIAL PLEXUS BLOCK FOR UPPER LIMB ORTHOPEDIC SURGERIES A MULTI - CENTER STUDY

    Directory of Open Access Journals (Sweden)

    Anish M

    2015-06-01

    Full Text Available BACKGROUND: Brachial plexus block is a suitable alternative to general anesthesia for surgeries of upper limb and it can be performed even in patients who are not adequately fit for general anesthesia. The significance of brachial plexus block has increased in recent years due to renewed interest in day care surgery. Lignocaine hydrochloride has been used extensively for brachial plexus block and it has the disadvantage of having short duration of action. Opioids when added to anesthetic mixtures may improve and prolo ng the action of local anesthetics during peripheral nerve blocks. Such postoperative pain control can reduce both narcotic requirements and narcotic induced side effects. Studies have shown the efficacy of opioids as analgesic adjuvants in prolonging the duration of brachial plexus block. With this background in mind, this study was conducted to compare the onset and duration of sensory and motor block produced by a mixture of lignocaine and adrenaline with that produced by a mixture of fentanyl, lignocain e and adrenaline. Aims: To assess the effectiveness of addition of fentanyl to a mixture of lignocaine and adrenaline in prolonging the duration of analgesia and motor block for upper limb orthopedic surgeries. MATERIALS AND METHODS: This multi - center rand omized control study was conducted in two tertiary care centers in 80 patients underwent elective upper limb orthopedic surgeries and they were allocated into two groups of 40 each group L and group F. the classical approach of supraclavicular brachial ple xus block. Drug used were 30 ml of lignocaine 1.5%+adrenaline 5mcg/ml + 0.5ml normal saline in group L and 30ml of lignocaine 1.5% + adrenaline 5mcg/ml + fentanyl 50 mcg in group F. Adequacy of block was assessed by the pin prick test and temperature test. Motor power was assessed by the modified Lowett scale. Sedation was monitored using the modified Ramsay scale. An assessment was made for onset of analgesia, onset of

  4. A STUDY OF SYMBOLIC RELATIONS IN PUBLIC TRANSPORT

    Directory of Open Access Journals (Sweden)

    ANDREI BALAN

    2011-04-01

    Full Text Available This paper presents an anthropological, exploratory study of the microsocial world of public transport. Our research focuses on the symbolic relations that are being established (verbally or nonverbally between urban transport travellers that do not know each other and the consequences these relations create. Modern urban configuration forces large numbers of individuals to share public space every day. When this space becomes restrictive, symbolic relations and interpersonal behaviors such as territoriality and personal space management become clearer. Due to overcrowding, public transport is the scene of one of the most restrictive public spaces in a city. The challenge was to observe and interpret daily, casual behaviors through a sociological and psychological scheme, following the methodological tradition established by Erving Goffman and the other symbolic interactionists. Finally, our study generates a number of hypotheses and explanatory models for common practices and behaviors in trams and metros regarded from a symbolic perspective.

  5. A STUDY OF SYMBOLIC RELATIONS IN PUBLIC TRANSPORT

    Directory of Open Access Journals (Sweden)

    Andrei B LAN

    2011-08-01

    Full Text Available This paper presents an anthropological, exploratory study of the microsocial world of public transport. Our research focuses on the symbolic relations that are being established (verbally or nonverbally between urban transport travellers that do not know each other and the consequences these relations create. Modern urban configuration forces large numbers of individuals to share public space every day. When this space becomes restrictive, symbolic relations and interpersonal behaviors such as territoriality and personal space management become clearer. Due to overcrowding, public transport is the scene of one of the most restrictive public spaces in a city. The challenge was to observe and interpret daily, casual behaviors through a sociological and psychological scheme, following the methodological tradition established by Erving Goffman and the other symbolic interactionists. Finally, our study generates a number of hypotheses and explanatory models for common practices and behaviors in trams and metros regarded from a symbolic perspective.

  6. Organ preconditioning: the past, current status, and related lung studies

    Institute of Scientific and Technical Information of China (English)

    LUH Shi-ping; YANG Pan-chyr

    2006-01-01

    Preconditioning (PC) has emerged as a powerful method for experimentally and clinically attenuating various types of organ injuries. In this paper related clinical and basic research issues on organ preconditioning issues were systemically reviewed.Since lung injuries, including ischemia-reperfusion and others, play important roles in many clinical results, including thromboembolism, trauma, thermal injury, hypovolemic and endotoxin shock, reimplantation response after organ transplantation, and many respiratory diseases in critical care. It is of interest to uncover methods, including the PCs, to protect the lung from the above injuries. However, related studies on pulmonary PC are relatively rare and still being developed, so we will review previous literature on experimental and clinical studies on pulmonary PC in the following paragraphs.

  7. Bicycle-related maxillofacial injuries: a double-center study

    NARCIS (Netherlands)

    Boffano, P.; Roccia, F.; Gallesio, C.; Karagozoglu, K.H.; Forouzanfar, T.

    2013-01-01

    Objective Bicycle-related injuries account for an important proportion of road injuries all over the world. As only few reports have focused on the characteristics of maxillofacial fractures sustained in bicycle accidents, the purpose of this study was to present and compare epidemiological data abo

  8. Bicycle-related maxillofacial injuries : a double-center study

    NARCIS (Netherlands)

    Boffano, Paolo; Roccia, Fabio; Gallesio, Cesare; Karagozoglu, K. Hakki; Forouzanfar, Tymour

    2013-01-01

    Objective. Bicycle-related injuries account for an important proportion of road injuries all over the world. As only few reports have focused on the characteristics of maxillofacial fractures sustained in bicycle accidents, the purpose of this study was to present and compare epidemiological data ab

  9. Teaching the Public Relations Case Studies/Campaigns Class.

    Science.gov (United States)

    Cottone, Laura Perkins

    The public relations case studies/campaigns class entails teaching students how to die and then come back to life. As students must learn to take a critical look at complex public and social issues, teachers should create an environment in which the students feel comfortable with the process of psychological reconstruction. Students must be taught…

  10. Comparative study on optical performance and visual outcomes between two diffractive multifocal lenses: AMO Tecnis ® ZMB00 and AcrySof ® IQ ReSTOR ® Multifocal IOL SN6AD1

    Directory of Open Access Journals (Sweden)

    Mario Augusto Pereira Dias Chaves

    2016-06-01

    Full Text Available ABSTRACT Purpose: To compare the optical performance and visual outcomes between two diffractive multifocal lenses: AMO Tecnis® ZMB00 and AcrySof® ReSTOR® SN6AD1. Methods: This prospective, non-randomized comparative study included the assessment of 74 eyes in 37 patients referred for cataract surgery and candidates for multifocal intraocular lens implants. Exclusion criteria included existence of any other eye disease, previous eye surgery, high axial myopia, preoperative corneal astigmatism of >1.00 cylindrical diopter (D, and intraoperative or postoperative complications. Ophthalmological evaluation included the measurement of uncorrected distance visual acuity (UDVA, corrected distance visual acuity (CDVA, distance-corrected near visual acuity (DCNVA, and distance-corrected intermediate visual acuity (DCIVA, with analysis of contrast sensitivity (CS, wavefront, and visual defocus curve. Results: Postoperative UDVA was 0.09 and 0.08 logMAR in the SN6AD1 and ZMB00 groups, respectively (p=0.868; postoperative CDVA was 0.04 and 0.02 logMAR in the SN6AD1 and ZMB00 groups, respectively (p=0.68; DCIVA was 0.17 and 0.54 logMAR in the SN6AD1 and ZMB00 groups, respectively (p=0.000; and DCNVA was 0.04 and 0.09 logMAR in the SN6AD1 and ZMB00 groups, respectively (p=0.001. In both cases, there was an improvement in the spherical equivalent and UDVA (p<0.05. Under photopic conditions, the SN6AD1 group had better CS at low frequencies without glare (p=0.04; however, the ZMB00 group achieved better sensitivity at high frequencies with glare (p=0.003. The SN6AD1 and ZMB00 lenses exhibited similar behavior for intermediate vision, according to the defocus curve; however, the ZMB00 group showed a shorter reading distance than the SN6AD1 group. There were no significant differences regarding aberrometry between the two groups. Conclusion: Both lenses promoted better quality of vision for both long and short distances and exhibited a similar behavior for

  11. Holographic Thermalization, Stability of AdS, and the FPU Paradox

    CERN Document Server

    Balasubramanian, Venkat; Green, Stephen R; Lehner, Luis; Liebling, Steven L

    2014-01-01

    For a real massless scalar field in general relativity with a negative cosmological constant, we uncover a large class of spherically symmetric initial conditions that are close to AdS, but whose numerical evolution does not result in black hole formation. According to the AdS/CFT dictionary, these bulk solutions are dual to states of a strongly interacting boundary CFT that fail to thermalize at late times. Furthermore, as these states are not stationary, they define dynamical CFT configurations that do not equilibrate. We develop a two-timescale perturbative formalism that captures both direct and inverse cascades of energy and agrees with our fully nonlinear evolutions in the appropriate regime. We also show that this formalism admits a large class of quasi-periodic solutions. Finally, we demonstrate a striking parallel between the dynamics of AdS and the classic Fermi-Pasta-Ulam-Tsingou problem.

  12. Woodworking injuries: a comparative study of work-related and hobby-related accidents.

    Science.gov (United States)

    Loisel, F; Bonin, S; Jeunet, L; Pauchot, J; Tropet, Y; Obert, L

    2014-10-01

    The primary objective of this study was to describe the injury characteristics and demographics of patients injured during woodworking activities, upon their arrival to the emergency department in a regional of France where this industry is prevalent. The secondary objective was to compare patient and injury characteristics for work-related and hobby-related accidents. A cohort of 87 patients who had suffered a woodworking accident over a two-year period was evaluated; 79 were available for follow-up. The context and circumstances of the accident, nature and location of the injuries and patient demographics were recorded. Hobby-related accidents accounted for two-thirds of the accidents (51/79). Most of the injured workers were either loggers (35%) or carpenters (46%). The hand was injured in 53 cases (67%). Work-related accidents resulted in significantly more serious consequences in terms of hospital stay, work stoppage, resumption of work or retraining than hobby-related accidents. For the workplace accidents, 86% occurred on new machines; more than 25% of the machines involved in accidents at home were over 15 years. Sixty-eight per cent of workers were wearing their safety gear, while only 31% of those injured during recreational woodworking wore the appropriate gear. Several elements of prevention should be improved: information about the need to maintain the equipment, protect the worker with suitable clothing, and learn which maneuvers are considered hazardous. Safety gear should be regularly inspected in the workplace.

  13. Nordic MCL3 study: 90Y-ibritumomab-tiuxetan added to BEAM/C in non-CR patients before transplant in mantle cell lymphoma

    DEFF Research Database (Denmark)

    Kolstad, Arne; Laurell, Anna; Jerkeman, Mats;

    2014-01-01

    The main objective of the MCL3 study was to improve outcome for patients not in complete remission (CR) before transplant by adding (90)Y-ibritumomab-tiuxetan (Zevalin) to the high-dose regimen. One hundred sixty untreated, stage II-IV mantle cell lymphoma patients maxi...

  14. Adalimumab added to a treat-to-target strategy with methotrexate and intra-articular triamcinolone in early rheumatoid arthritis increased remission rates, function and quality of life. The OPERA Study

    DEFF Research Database (Denmark)

    Hørslev-Petersen, Kim; Hetland, Merete Lund; Junker, Peter

    2014-01-01

    OBJECTIVES: An investigator-initiated, double-blinded, placebo-controlled, treat-to-target protocol (Clinical Trials:NCT00660647) studied whether adalimumab added to methotrexate and intra-articular triamcinolone as first-line treatment in early rheumatoid arthritis (ERA) increased the frequency ...

  15. A randomised, double-blind, placebo-controlled, multicentre study of the safety and efficacy of BIOBYPASS (AdGVVEGF121.10NH) gene therapy in patients with refractory advanced coronary artery disease: the NOVA trial

    DEFF Research Database (Denmark)

    Kastrup, Jens; Jørgensen, Erik; Fuchs, Shmuel

    2011-01-01

    Genes encoding vascular endothelial growth factor (VEGF) can potentially augment myocardial perfusion in patients with coronary artery disease (CAD). We conducted a randomised, double-blind, placebo-controlled gene therapy study with the adenovirus carrying VEGF121 (BIOBYPASS [AdGVVEGF121.10NH])....

  16. Integrable strings for AdS/CFT

    CERN Document Server

    Borsato, Riccardo

    2016-01-01

    In this PhD thesis we review some aspects of integrable models related to string backgrounds or their deformations. In the first part we develop methods to obtain exact results in the AdS3/CFT2 correspondence. We consider the AdS_3 x S^3 x T^4 background with pure Ramond-Ramond flux and we find the all-loop worldsheet S-matrix by exploiting the symmetries of the model in light-cone gauge. As we naturally include the massless modes on the worldsheet, we derive the full set of Bethe-Yang equations. In the massive sector we give also a spin-chain description and we write down solutions compatible with crossing for the scalar factors which are not constrained by simmetries. In the second part of the thesis we consider the so-called "eta-deformation" of the superstring on AdS_5 x S^5. We first discuss the effects of the deformation at the level of the bosonic sigma-model, and we match the tree-level worldsheet scattering processes to the expansion of the q-deformed S-matrix. To identify the missing Ramond-Ramond f...

  17. Security Challenges and Attacks in Mobile Ad Hoc Networks

    Directory of Open Access Journals (Sweden)

    CH.V. Raghavendran

    2013-09-01

    Full Text Available Mobile Ad hoc Network (MANET is an autonomous collection of mobile nodes that form a temporary network without of any existing network infrastructure or central access point. The popularity of these networks created security challenges as an important issue. The traditional routing protocols perform well with dynamically changing topology but are not designed to defense against security challenges. In this paper we discuss about current challenges in an ad hoc environment which includes the different types of potential attacks that are possible in the Mobile Ad hoc Networks that can harm its working and operation. We have done literature study and gathered information relating to various types of attacks. In our study, we have found that there is no general algorithm that suits well against the most commonly known attacks. But the complete security solution requires the prevention, detection and reaction mechanisms applied in MANET. To develop suitable security solutions for such environments, we must first understand how MANETs can be attacked. This paper provides a comprehensive study of attacks against mobile ad hoc networks. We present a detailed classification of the attacks against MANETs.

  18. Simplified TBA equations of the AdS5 × S5 mirror model

    NARCIS (Netherlands)

    Arutyunov, G.E.; Frolov, S.

    2009-01-01

    We use the recently found integral representation for the dressing phase in the kinematic region of the mirror theory to simplify the TBA equations for the AdS5 × S5 mirror model. The resulting set of equations provides an efficient starting point for both analytic and numerical studies.

  19. Classical strings in $AdS_4\\times\\mathbb{CP}^3$ with three angular momenta

    CERN Document Server

    Giardino, Sergio

    2011-01-01

    In this paper, rotating strings in three directions of $AdS_4 \\times \\mathbb{CP}^3$ geometry are studied; its divergent energy limit, and conserved charges are also determined. An interpretation of these configurations as either giant magnons or spiky strings are discussed.

  20. Searching for Causality in AdS/CFT

    Science.gov (United States)

    Kelly, William R.

    String theory with certain asymptotically AdS boundary conditions can be defined non-perturbatively using the AdS/CFT correspondence, which reformulates the theory in terms of a non-gravitational quantum field theory in a lower dimensional spacetime. In this way many of the subtleties of quantizing gravity are circumvented, however, the price of this simplification is that locality is no longer manifest, even in an approximate sense. In this dissertation we study features of asymptotically AdS spacetimes related to causality and search for these properties in the dual CFT description. We begin by reviewing some of the salient features of the correspondence and studying some puzzles related to the Ryu-Takayanagi conjecture. We then show that the notion of boundary causality associated with the Gao-Wald theorem implies that holographic CFT's on Minkowski space must satisfy the averaged null energy condition (ANEC). The ANEC is a quasilocal energy condition that requires the integrated null energy on a null line to be positive. Any violations of this condition in a holographic theory would result in "causal shortcuts'' through the bulk spacetime which would allow propagation outside of the light cone in the CFT. We next study causal wedges associated with subregions of the boundary and argue that these regions of the bulk spacetime are associated with a particular coarse-graining of the CFT reduced density matrix. In particular, we conjecture that the area of the codimension-two boundary of these wedges is equal to a particular coarse-grained entropy which we name the 'one-point entropy.' We present several suggestive examples in which the conjecture holds as well as a proof that it holds to leading order in a class of spacetimes with a bulk first law. In an appendix we explain how the conjecture is equivalent to a statement about the classical Einstein equation which in principle could be rigorously proven or falsified.

  1. Two Case Studies Related to Total Knee Arthroplasty

    Science.gov (United States)

    Hale, David

    2016-01-01

    Objectives: Report on Two Case Studies related to Total Knee Arthroplasty Previously Discussed by AKS Members Methods: Case Series Case 1: A 76 year old woman requiring a right total knee replacement in the presence of marked dystrophic calcification affecting the quadriceps tendon on a background of having sustained a post operative quadriceps tendon rupture post left TKR in 2013 Case 2: Management issues related to performing a TKR in a 80 year old woman with a possible past history of TB affecting the joint Conclusion: Both procedures went smoothly and particularly as advice was given by AKS members, these are presented largely for feedback.

  2. Searching for AdS_3 waves and Asymptotically Lifshitz black holes in R^3-NMG

    CERN Document Server

    Anastasiou, Giorgos G; Vagenas, Elias C

    2013-01-01

    In this paper we consider the structure of the $AdS_3$ vacua in $R^3$ expansion of the New Massive Gravity ($R^3$-NMG). We obtain the degeneracies of the $AdS_3$ vacua at several points of the parametric space. Additionally, following a specific analysis we show that $AdS_3$ wave solutions are present. Using these wave solutions, we single out two special points of the parametric space for which logarithmic terms appear in the solutions. The first one is a point at which the effective mass of the wave profile which is interpreted as a scalar mode, completely saturates the Breitenlohner-Freedman bound of the $AdS_3$ space in which the wave is propagating. The second special point is a point at which the central charge of the theory vanishes. Furthermore, we investigate the possibility of asymptotically Lifshitz black solutions to be present in the three-dimensional $R^3$-NMG. We derive analytically the Lifshitz vacua considering specific relations between the mass parameters of $R^3$-NMG. A certain polynomial ...

  3. Internet Advertising. Google AdWords versus Facebook Ads

    Directory of Open Access Journals (Sweden)

    Paul PAŞCU

    2014-05-01

    Full Text Available This article describes how to use the applications for Internet advertising, Google AdWords and Facebook Ads. Our attempt is to present the advantages and disadvantages of each of them, the costs and benefits, a useful aspect for companies that plan to start advertising campaigns on the Internet.

  4. Nuovi servizi a valore aggiunto per riviste elettroniche di studi classici New Value-Added Services for Electronic Journals in Classics

    Directory of Open Access Journals (Sweden)

    Matteo Romanello

    2011-06-01

    Full Text Available E-journals are undoubtedly less widespread in the Humanities than in the Scientific, Technical and Medical (STM field. This is not just because of a lag in Humanities journals' development, but also because of the different extent at what electronic publishing technologies fit respectively the different nature and requirements of disciplines. The wide range of functionalities and services that can be offered online in addition to the print copy of a journal is one of the most important differences between paper-based and electronic publishing. Value Added Services (VAS represent also a key aspect to be leveraged in the development of a sustainable business model for open access journals. VAS need to be though carefully. To provide them comes at a cost and it is a process that can just partly be automated. The paper aims at designing a new model for Classics e-journals specifically tailored on classicists' needs, identifying a set of functionalities that may be provided by e-journals on the basis of a deep understanding of the field and of recent user studies. The implementation of such functionalities and the automatisation of the process needed to enable them are then discussed in detail.Le riviste elettroniche sono decisamente meno diffuse in ambito umanistico piuttosto che scientifico, non tanto per un ritardo delle discipline umanistiche in questo senso quanto per la diversa rispondenza del medium alla disciplina stessa. La vasta gamma di funzionalità e servizi che possono essere offerti online in aggiunta alla copia stampata di una rivista costituisce una delle più importanti differenze tra l'editoria tradizionale e quella elettronica. L'attuale offerta ed i futuri sviluppi delle riviste nell'ambito delle scienze umane sono analizzati attraverso i dati raccolti con un sondaggio sulle caratteristiche di una rivista elettronica, del tipo di diritti impiegati, degli strumenti elettronici usati nel lavoro editoriale e degli elementi che ne

  5. Predicting AD conversion: comparison between prodromal AD guidelines and computer assisted PredictAD tool.

    Directory of Open Access Journals (Sweden)

    Yawu Liu

    Full Text Available To compare the accuracies of predicting AD conversion by using a decision support system (PredictAD tool and current research criteria of prodromal AD as identified by combinations of episodic memory impairment of hippocampal type and visual assessment of medial temporal lobe atrophy (MTA on MRI and CSF biomarkers.Altogether 391 MCI cases (158 AD converters were selected from the ADNI cohort. All the cases had baseline cognitive tests, MRI and/or CSF levels of Aβ1-42 and Tau. Using baseline data, the status of MCI patients (AD or MCI three years later was predicted using current diagnostic research guidelines and the PredictAD software tool designed for supporting clinical diagnostics. The data used were 1 clinical criteria for episodic memory loss of the hippocampal type, 2 visual MTA, 3 positive CSF markers, 4 their combinations, and 5 when the PredictAD tool was applied, automatically computed MRI measures were used instead of the visual MTA results. The accuracies of diagnosis were evaluated with the diagnosis made 3 years later.The PredictAD tool achieved the overall accuracy of 72% (sensitivity 73%, specificity 71% in predicting the AD diagnosis. The corresponding number for a clinician's prediction with the assistance of the PredictAD tool was 71% (sensitivity 75%, specificity 68%. Diagnosis with the PredictAD tool was significantly better than diagnosis by biomarkers alone or the combinations of clinical diagnosis of hippocampal pattern for the memory loss and biomarkers (p≤0.037.With the assistance of PredictAD tool, the clinician can predict AD conversion more accurately than the current diagnostic criteria.

  6. AdS5 backgrounds with 24 supersymmetries

    Science.gov (United States)

    Beck, S.; Gutowski, J.; Papadopoulos, G.

    2016-06-01

    We prove a non-existence theorem for smooth AdS 5 solutions with connected, compact without boundary internal space that preserve strictly 24 supersymmetries. In particular, we show that D = 11 supergravity does not admit such solutions, and that all such solutions of IIB supergravity are locally isometric to the AdS 5 × S 5 maximally supersymmetric background. Furthermore, we prove that (massive) IIA supergravity also does not admit such solutions, provided that the homogeneity conjecture for massive IIA supergravity is valid. In the context of AdS/CFT these results imply that if gravitational duals for strictly mathcal{N}=3 superconformal theories in 4-dimensions exist, they are either singular or their internal spaces are not compact.

  7. Coset construction of AdS particle dynamics

    CERN Document Server

    Heinze, Martin; Megrelidze, Luka

    2016-01-01

    We analyze dynamics of the AdS$_{N+1}$ particle realized on the coset SO$(2,N)/$SO$(1,N)$. Hamiltonian reduction provides the physical phase space in terms of the coadjoint orbit obtained by boosting a timelike element of ${\\frak so}(2,N)$. We show equivalence of this approach to geometric quantization and to the SO$(N)$ covariant oscillator description, for which the boost generators entail a complicated operator ordering. As an alternative scheme, we introduce dual oscillator variables and derive their algebra at the classical and the quantum level. This simplifies the calculations of the commutators for the boost generators and leads to unitary irreducible representations of ${\\frak so}(2,N)$ for all admissible values of the mass parameter. We furthermore discuss a SO$(N)$ covariant supersymmetric extensions of the oscillator quantization, with its realization for superparticles in AdS$_2$ and AdS$_3$ given by recent works.

  8. Instantons and quark zero modes in AdS/QCD

    DEFF Research Database (Denmark)

    Bechi, Jacopo

    2009-01-01

    In this paper the quark zero modes creation effect is studied in the context of the AdS/QCD approach. This effect is generated, in presence of instantons, by a new that can be added in the bulk.......In this paper the quark zero modes creation effect is studied in the context of the AdS/QCD approach. This effect is generated, in presence of instantons, by a new that can be added in the bulk....

  9. Effects of added involvement from concerned significant others in internet-delivered CBT treatments for problem gambling: study protocol for a randomised controlled trial

    Science.gov (United States)

    Nilsson, Anders; Andersson, Gerhard; Hellner Gumpert, Clara

    2016-01-01

    Introduction Problem gambling is a public health concern affecting ∼2.3% of the Swedish population. Problem gambling also severely affects concerned significant others (CSOs). Several studies have investigated the effect of individual treatments based on cognitive–behavioural therapy (CBT), but less is known of the effect of involving CSOs in treatment. This study aims to compare an intervention based on behavioural couples therapy (BCT), involving a CSO, with an individual CBT treatment to determine their relative efficacy. BCT has shown promising results in working with substance abuse, but this is the first time it is used as an intervention for problem gambling. Both interventions will be internet-delivered, and participants will receive written support and telephone support. Methods and analysis A sample of 120 couples will be randomised to either the BCT condition, involving the gambler and the CSO, or the CBT condition, involving the gambler alone. Measures will be conducted weekly and at 3, 6 and 12 months follow-up. The primary outcome measure is gambling behaviour, as measured by Timeline Followback for Gambling. This article describes the outline of the research methods, interventions and outcome measures used to evaluate gambling behaviour, mechanisms of change and relationship satisfaction. This study will be the first study on BCT for problem gambling. Ethics and dissemination This study has been given ethical approval from the regional ethics board of Stockholm, Sweden. It will add to the body of knowledge as to how to treat problem gambling and how to involve CSOs in treatment. The findings of this study will be published in peer-reviewed journals and published at international and national conferences. Trial registration number NCT02543372; Pre-results. PMID:27670519

  10. A twin study of perfume-related respiratory symptoms.

    Science.gov (United States)

    Elberling, J; Lerbaek, A; Kyvik, K O; Hjelmborg, J

    2009-11-01

    Respiratory symptoms from environmental perfume exposure are main complaints in patients with multiple chemical sensitivities and often coincide with asthma and or eczema. In this population-based twin study we estimate the heritability of respiratory symptoms related to perfume and if co-occurrences of the symptoms in asthma, atopic dermatitis, hand eczema or contact allergy are influenced by environmental or genetic factors common with these diseases. In total 4,128 twin individuals (82%) responded to a questionnaire. The heritability of respiratory symptoms related to perfume is 0.35, 95%CI 0.14-0.54. Significant associations (pperfume-related respiratory symptoms and asthma, atopic dermatitis, hand eczema or contact allergy are not attributable to shared genetic or shared environmental/familial factors, except possibly for atopic dermatitis where genetic pleiotropy with respiratory symptoms to perfume is suggested by an estimated genetic correlation of 0.39, 95%CI 0.09-0.72.

  11. Factors related to physical activity: a study of adolescents.

    Science.gov (United States)

    Vilhjalmsson, R; Thorlindsson, T

    1998-09-01

    Although the consequences of physical activity have been carefully documented, less is known about its correlates, particularly among children and youth. Based on a representative national survey of 1131 Icelandic adolescents, the study examined various physical, psychological, social and demographic factors related to physical activity. Male sex, significant others' involvement in physical activity (father, friend and older brother), sociability, perceived importance of sport and of health improvement and satisfaction with mandatory gym classes in school, were all related to more involvement, whereas hours of paid work and TV-viewing were related to less. Furthermore, the data suggested that the influence of friend's participation in physical activity depends on his or her emotional significance. Influential others appeared to affect males and females in the same way. The meaning of the results and their implications for future research are discussed.

  12. Alcohol effects on family relations: a case study.

    Science.gov (United States)

    Reinaldo, Amanda Márcia Dos Santos; Pillon, Sandra Cristina

    2008-01-01

    Problems related to alcohol abuse have been associated to different factors, regardless of the causes attributed to this phenomenon. Alcohol consumption and dependence is considered a public health problem and deserve attention because of the social, work, family, physical, legal and violence-related risks it represents. This study aimed to identify the effects of alcoholism on family relations and, by means of case management, to encourage the recovery of these relationships. The results show that the problems caused by alcohol abuse impose profound suffering to family members, which contributes to high levels of interpersonal conflict, domestic violence, parental inadequacy, child abuse and negligence, financial and legal difficulties, in addition to clinical problems associated to it.

  13. The Quest for Value-Added Products from Carbon Dioxide and Water in a Dielectric Barrier Discharge: A Chemical Kinetics Study.

    Science.gov (United States)

    Snoeckx, Ramses; Ozkan, Alp; Reniers, Francois; Bogaerts, Annemie

    2017-01-20

    Recycling of carbon dioxide by its conversion into value-added products has gained significant interest owing to the role it can play for use in an anthropogenic carbon cycle. The combined conversion with H2 O could even mimic the natural photosynthesis process. An interesting gas conversion technique currently being considered in the field of CO2 conversion is plasma technology. To investigate whether it is also promising for this combined conversion, we performed a series of experiments and developed a chemical kinetics plasma chemistry model for a deeper understanding of the process. The main products formed were the syngas components CO and H2 , as well as O2 and H2 O2 , whereas methanol formation was only observed in the parts-per-billion to parts-per-million range. The syngas ratio, on the other hand, could easily be controlled by varying both the water content and/or energy input. On the basis of the model, which was validated with experimental results, a chemical kinetics analysis was performed, which allowed the construction and investigation of the different pathways leading to the observed experimental results and which helped to clarify these results. This approach allowed us to evaluate this technology on the basis of its underlying chemistry and to propose solutions on how to further improve the formation of value-added products by using plasma technology.

  14. A study on the change in the phase transition temperature of TiSi sub 2 by adding the Zr element on different Si substrates

    CERN Document Server

    Yoon, S H

    1999-01-01

    The stabilization of C49 TiSi sub 2 at high temperature was investigated by adding Zr element to Ti-silicide both on single crystalline Si(100) and amorphous Si substrates. This stabilization of the C49 TiSi sub 2 phase, which exhibits lower surface and interface energies than those of the C54 TiSi sub 2 phase, was expected to suppress the problems of Ti-silicide, such as the phase transition and the agglomeration. Ti and Zr films of 40 nm were co-deposited on Si substrates in a dual e-beam evaporation system equipped with an ion pump and at a base pressure of approx 5x10 sup - sup 9 Torr. The amounts of Zr contents added to the Ti-silicide were 5, 10 and 20 atomic %, and the thicknesses were monitored by in-situ quartz-crystal thickness monitors. After the deposition, films were annealed by using an ex-situ vacuum furnace at temperatures between 600 .deg. C and 900 .deg. C in 100 .deg. C increments. The phase identification and the chemical compositions were investigated by X-ray diffraction (XRD) and Auger ...

  15. Excess conductivity analysis in YBa2Cu3O7-d added with SiO2 nanoparticles and nanowires: Comparative study

    Science.gov (United States)

    Al-Otaibi, A. L.; Almessiere, M. A.; Salem, M. Ben; Azzouz, F. Ben

    2016-07-01

    The effect of nanosized silicon oxide nanoparticles (denoted NP-SiO2) and nanowires (denoted NW-SiO2) additions during the final processing stage on electrical fluctuation conductivity of polycrystalline YBa2Cu3Oy (Y-123 for brevity) in the mean field region has been reported. Series of samples were synthesized in air using a standard solid-state reaction technique by adding nanosized entities up to 0.5 wt.%. Phases, microstructure and superconductivity properties have been systematically investigated using X-ray diffraction (XRD), transmission electron microscopy (TEM) and electrical measurements. TEM investigations show the presence of inhomogeneities embedded in the superconducting matrix along with the presence of columnar defects in the case of SiO2 nanoparticles added samples, however nanowires tend to agglomerate by entangling with each other in the intergrain regions. The fluctuation conductivity was analyzed as a function of reduced temperature using the Aslamazov-Larkin model. Using the Lawrence-Doniach equations, the Ginzburg-Landau (GL) number (NG) and equations, the coherence length, the effective layer thickness, the lower critical field Bc1(0), the upper critical field Bc2(0) and the critical current density Jc(0) were estimated. It was found that the addition of an optimum concentration of SiO2 nanomaterials, that depends on the shape, effectively controlled the microstructure, the grains coupling and hence improved the physical properties of Y-123 compound.

  16. Study on the mortality in Ecuador related to dietary factors

    Directory of Open Access Journals (Sweden)

    Juan Alejandro Neira-Mosquera

    2013-10-01

    Full Text Available Diet is an important factor related to the development of numerous diseases. In developing countries like Ecuador, this aspect is not considered as priority however, the study of the incidence of certain diet-related diseases could help to assess consumption habits of a country from a Public Health perspective and support national nutrition policies and programs. The objective the present study is to investigate the mortality rate of certain diet-related diseases in Ecuador and its possible relationship with Ecuadorian consumption habits. For that, mortality rates (2001-2008 associated with five different disease groups related to dietary factors (cancer of colon, cerebrovascular diseases, cardiovascular diseases, diabetes mellitus and liver diseases were collected, analyzed and compared to consumption patterns in Ecuador. According to results, Ecuador has a low level of cancer of colon in comparison with developed countries (e.g. Spain. The group with the highest number of deaths corresponded to cardiovascular diseases followed by cerebrovas-cular diseases. The mortality study per province revealed that Amazonian provinces showed few deaths in relation to other provinces in Ecuador. This could be due to different factors including fails in the disease surveillance information systems, environmental factors and consumption patterns. In this sense, further investigation on native products consumption such as "chontaduro" might help to find valuable foods contributing to healthier Ecuadorian diet. These results, though preliminary, evidence that a major effort should be made by national and international organisations to collect data on consumption patterns and nutritional aspects of the Ecuadorian population in order to better support the development of effective food security and nutrition policies.

  17. Study on the mortality in Ecuador related to dietary factors.

    Science.gov (United States)

    Neira-Mosquera, Juan Alejandro; Pérez-Rodríguez, Fernando; Sánchez-Llaguno, Sungey; Moreno Rojas, Rafael

    2013-01-01

    Diet is an important factor related to the development of numerous diseases. In developing countries like Ecuador, this aspect is not considered as priority however, the study of the incidence of certain diet-related diseases could help to assess consumption habits of a country from a Public Health perspective and support national nutrition policies and programs. The objective the present study is to investigate the mortality rate of certain diet-related diseases in Ecuador and its possible relationship with Ecuadorian consumption habits. For that, mortality rates (2001-2008) associated with five different disease groups related to dietary factors (cancer of colon, cerebrovascular diseases, cardiovascular diseases, diabetes mellitus and liver diseases) were collected, analyzed and compared to consumption patterns in Ecuador. According to results, Ecuador has a low level of cancer of colon in comparison with developed countries (e.g. Spain). The group with the highest number of deaths corresponded to cardiovascular diseases followed by cerebrovascular diseases. The mortality study per province revealed that Amazonian provinces showed few deaths in relation to other provinces in Ecuador. This could be due to different factors including fails in the disease surveillance information systems, environmental factors and consumption patterns. In this sense, further investigation on native products consumption such as "chontaduro" might help to find valuable foods contributing to healthier Ecuadorian diet. These results, though preliminary, evidence that a major effort should be made by national and international organisations to collect data on consumption patterns and nutritional aspects of the Ecuadorian population in order to better support the development of effective food security and nutrition policies.

  18. Sub-AdS Scale Locality in AdS$_3$/CFT$_2$

    CERN Document Server

    Belin, Alexandre; Jefferson, Robert A; Kabir, Laurens

    2016-01-01

    We investigate sub-AdS scale locality in a weakly coupled toy model of the AdS$_3$/CFT$_2$ correspondence. We find that this simple model has the correct density of states at low and high energies to be dual to Einstein gravity coupled to matter in AdS$_3$. Bulk correlation functions also have the correct behavior at leading order in the large $N$ expansion, but non-local effects emerge at order $1/N$. Our analysis leads to the conjecture that any large $N$ CFT$_2$ that is modular invariant and has the right low-energy density of states is dual to a gravitational theory with sub-AdS scale locality.

  19. Epidemiological aspects of studying work-related musculoskeletal disorders.

    Science.gov (United States)

    Driscoll, Tim

    2011-02-01

    There are many challenges to conducting valid epidemiological research of work-related musculoskeletal disorders and interpreting reports describing the results. In particular, these concern the basic study design, selection of subjects, measurement of exposure and outcome, control of confounding and the limitations of workers' compensation data systems. Researchers and people interested in the research results need to be aware of the major potential problems and pay careful attention to them when designing, conducting and using the results of such research.

  20. Ultraviolet asymptotics for quasiperiodic AdS_4 perturbations

    CERN Document Server

    Craps, Ben; Jai-akson, Puttarak; Vanhoof, Joris

    2015-01-01

    Spherically symmetric perturbations in AdS-scalar field systems of small amplitude epsilon approximately periodic on time scales of order 1/epsilon^2 (in the sense that no significant transfer of energy between the AdS normal modes occurs) have played an important role in considerations of AdS stability. They are seen as anchors of stability islands where collapse of small perturbations to black holes does not occur. (This collapse, if it happens, typically develops on time scales of the order 1/epsilon^2.) We construct an analytic treatment of the frequency spectra of such quasiperiodic perturbations, paying special attention to the large frequency asymptotics. For the case of a self-interacting phi^4 scalar field in a non-dynamical AdS background, we arrive at a fairly complete analytic picture involving quasiperiodic spectra with an exponential suppression modulated by a power law at large mode numbers. For the case of dynamical gravity, the structure of the large frequency asymptotics is more complicated....

  1. Characteristics of Period-Adding Bursting Bifurcation Without Chaos in the Chay Neuron Model

    Institute of Scientific and Technical Information of China (English)

    YANG Zhuo-Qin; LU Qi-Shao

    2004-01-01

    @@ A period-adding bursting sequence without bursting-chaos in the Chay neuron model is studied by bifurcation analysis. The genesis of each periodic bursting is separately evoked by the corresponding periodic spiking patterns through two period-doubling bifurcations, except for the period-1 bursting occurring via Hopf bifurcation. Hence,it is concluded that this period-adding bursting bifurcation without chaos has a compound bifurcation structure closely related to period-doubling bifurcations of periodic spiking in essence.

  2. Alzheimer′s disease research is at a crucial tipping point:Interpreting of AD related new expositions published in Lancet%处于研究转折中的阿尔茨海默病--解读2016年Lancet新论述

    Institute of Scientific and Technical Information of China (English)

    韩璎; 戴建平

    2016-01-01

    阿尔茨海默病( Alzheimer′s disease ,AD)的发现已逾百年,目前我们对此病的病因和发病机制仍然知之甚少。自1994年以来,随着各国政府的积极介入和相关科学技术的迅猛发展,AD研究不断深入。2016年发表在Lancet 杂志的Alzheimer′s disease一文就AD研究进展作了新的论述。文章从AD自身理念研究、中西方AD患病差异及AD临床药物试验研究方面对此文进行解读。%Alzheimer′s disease has been found for more than 100 years.But its etiology and pathogenesis remains unknown .With the interference of governments worldwide and the development of science and technology , AD research goes deeper since 1994.An article was entitled "Alzheimer′s disease", published in the Lancet in 2016, reviews the new progress on AD research .We will interpreting of AD related new exposi-tions from the following aspects: ① Research on the concept of AD; ②Differences in prevalence of AD between Eastern and Western countries ;③Clinical trials of AD drugs .

  3. BPS preons and the AdS-M-algebra

    CERN Document Server

    Bandos, Igor A

    2008-01-01

    We present here the AdS generalization of BPS preons, which were introduced as the hypothetical constituents of M-theory preserving all but one supersymmetries. Our construction, suggested by the relation of `lower dimensional preons' with higher spin theories, can be considered as a deformation of the M-algebraic description of the single supersymmetry broken by a preon, and provides another reason to identify the AdS generalization of the M-algebra, which we call the AdS-M-algebra, with osp(1|32).

  4. BPS preons and the AdS-M-algebra

    Science.gov (United States)

    Bandos, Igor A.; de Azcárraga, José A.

    2008-04-01

    We present here the AdS generalization of BPS preons, which were introduced as the hypothetical constituents of M-theory preserving all but one supersymmetries. Our construction, suggested by the relation of `lower dimensional preons' with higher spin theories, can be considered as a deformation of the M-algebraic description of the single supersymmetry broken by a preon, and provides another reason to identify the AdS generalization of the M-algebra, which we call the AdS-M-algebra, with osp(1|32).

  5. Hairy Black Holes in AdS$_5\\times S^5$

    CERN Document Server

    Markeviciute, J

    2016-01-01

    We use numerical methods to exhaustively study a novel family of hairy black hole solutions in AdS$_5$. These solutions can be uplifted to solutions of type IIB supergravity with AdS$_5\\times S^5$ asymptotics and are thus expected to play an important role in our understanding of AdS/CFT. We find an intricate phase diagram, with the aforementioned family of hairy black hole solutions branching from the Reissner-Nordstr\\"om black hole at the onset of the superradiance instability. We analyse black holes with spherical and planar horizon topology and explain how they connect in the phase diagram. Finally, we detail their global and local thermodynamic stability across several ensembles.

  6. Black Hole Formation in AdS Einstein-Gauss-Bonnet Gravity

    CERN Document Server

    Deppe, Nils; Frey, Andrew R; Kunstatter, Gabor

    2016-01-01

    AdS spacetime has been shown numerically to be unstable against a large class of arbitrarily small perturbations. In arXiv:1410.1869, the authors presented a preliminary study of the effects on stability of changing the local dynamics by adding a Gauss-Bonnet term to the Einstein action. Here we provide further details as well as new results with improved numerical methods. In particular, we elucidate new structure in Choptuik scaling plots. We also provide evidence of chaotic behavior at the transition between immediate horizon formation and horizon formation after the matter pulse reflects from the AdS conformal boundary. Finally, we present data suggesting the formation of naked singularities in spacetimes with ADM mass below the algebraic bound for black hole formation.

  7. 挤压加酶玉米初淀粉制备高 DE 值糖浆试验研究%The Experiment Study on Extruded Raw Maize Starch Added Enzyme Used for Production of High DE Value Syrup

    Institute of Scientific and Technical Information of China (English)

    申勋宇; 扬玉平; 申德超

    2014-01-01

    本试验用单螺杆挤压机对玉米粗淀粉进行挤压加工,研究挤压-糖化系统参数(套筒温度、原料含水率、挤压前加酶量、液化时加酶量和糖化时加酶量)对挤出物制备糖浆的DE值的影响规律。同时,对挤出物制取高DE值糖浆的试验结果进行了验证。%The maize raw starch added enzyme was extruded by single screw .Above extrudate was used for production of maize starch syrup .The influence regularity of extrusion-saccharification system parameters which include the barrel tem-perature , moisture content percentage of raw maize starch ,enzyme dosage added before extrusion , enzyme dosage added while liquifying , enzyme dosage added when saccharifying on the syrup DE value was studied in this paper .Meanwhile the experiment results for production of high DE value syrup were verified .

  8. Data Confidentiality in Mobile Ad hoc Networks

    CERN Document Server

    Aldabbas, Hamza; Janicke, Helge; Al-Bayatti, Ali; 10.5121/ijwmn.2012.4117

    2012-01-01

    Mobile ad hoc networks (MANETs) are self-configuring infrastructure-less networks comprised of mobile nodes that communicate over wireless links without any central control on a peer-to-peer basis. These individual nodes act as routers to forward both their own data and also their neighbours' data by sending and receiving packets to and from other nodes in the network. The relatively easy configuration and the quick deployment make ad hoc networks suitable the emergency situations (such as human or natural disasters) and for military units in enemy territory. Securing data dissemination between these nodes in such networks, however, is a very challenging task. Exposing such information to anyone else other than the intended nodes could cause a privacy and confidentiality breach, particularly in military scenarios. In this paper we present a novel framework to enhance the privacy and data confidentiality in mobile ad hoc networks by attaching the originator policies to the messages as they are sent between nod...

  9. Introduction to AdS/CFT correspondence

    CERN Document Server

    Nastase, Horatiu

    2015-01-01

    Providing a pedagogical introduction to the rapidly developing field of AdS/CFT correspondence, this is one of the first texts to provide an accessible introduction to all the necessary concepts needed to engage with the methods, tools and applications of AdS/CFT. Without assuming anything beyond an introductory course in quantum field theory, it begins by guiding the reader through the basic concepts of field theory and gauge theory, general relativity, supersymmetry, supergravity, string theory and conformal field theory, before moving on to give a clear and rigorous account of AdS/CFT correspondence. The final section discusses the more specialised applications, including QCD, quark-gluon plasma and condensed matter. This book is self-contained and learner-focused, featuring numerous exercises and examples. It is essential reading for both students and researchers across the fields of particle, nuclear and condensed matter physics.

  10. The spectrum of tachyons in AdS/CFT

    NARCIS (Netherlands)

    Bajnok, Z.; Drukker, N.; Hegedus, A.; Nepomechie, R.I.; Palla, L.; Sieg, C.; Suzuki, R.

    2013-01-01

    We analyze the spectrum of open strings stretched between a D-brane and an anti-D-brane in planar AdS/CFT using various tools. We focus on open strings ending on two giant gravitons with different orientation in AdS5×S5 and study the spectrum of string excitations using the following approaches: ope

  11. The spectrum of tachyons in AdS/CFT

    NARCIS (Netherlands)

    Bajnok, Zoltán; Drukker, Nadav; Hegedus, Árpád; Nepomechie, Rafael I.; Palla, László; Sieg, Christoph; Suzuki, Ryo

    2014-01-01

    We analyze the spectrum of open strings stretched between a D-brane and an anti-D-brane in planar AdS/CFT using various tools. We focus on open strings ending on two giant gravitons with different orientation in AdS 5 × S 5 and study the spectrum of string excitations using the following approaches:

  12. On the Translation of Semantic Relations: an empirical study

    Directory of Open Access Journals (Sweden)

    Louise Denver

    2002-01-01

    Full Text Available In this article, the transfer of semantic relations between propositions is discussed based on a pilot study carried out for didactic purposes at the Copenhagen Business School. The relations studied were unmarked in the source text (ST and the research aimed at investigating to what extent the translation of textual cohesion is the object of mental processing by semi-professional opt for a strategy involving the explicitation in the target text (TT of semantic relations which can be deduced from the ST by means of inferences.Neste artigo, discute-se a transferência de relações semânticas entre proposições com base em um estudo piloto com objetivos didáticos realizado na Copenhagen Business School. As relações analisadas eram não marcadas no texto de partida (TP. Procura-se investigar até que ponto a tradução da coesão textual é objeto de processamento mental por tradutores quase profissionais durante o processo de tradução e até que ponto os tradutores quase profissionais optam por uma estratégia envolvendo explicitação no texto de chegada (TC das relações semânticas que podem ser deduzidas a partir do TP através de inferências.

  13. Relations of power in public schools: a case study

    Directory of Open Access Journals (Sweden)

    Maria Custódia Jorge Rocha

    2014-04-01

    Full Text Available In this paper, based on a few authors who see power as a substantive element – instituted power – and others who consider it as an action verb – instituting power (ROCHA, 2007 –, highlighting some types of power relevant in sociological and organizational research on schools, we present empirical data and institutional discourses, enabled by a case study of qualitative nature. Thus, we can say that relations of power in schools both allow the strengthening of hierarchical and asymmetrical relations of power that exist between institutional players and enable the creation of new “circles of power” that can be promptly activated or can be object of a modernization process held in a more or less generalized manner. This may be reinforced and introduced to players/students, our main target of study, as the most legitimate object, superseding all others but not canceling them. The key objective is to present school organization as a highly complex environment, especially when considered in the light of the multiple and cumulative relations of power that emerge and are materialized.

  14. EVH Black Holes, AdS3 Throats and EVH/CFT Proposal

    CERN Document Server

    Sheikh-Jabbaria, M M

    2011-01-01

    Within class of generic black holes there are extremal black holes (with vanishing Hawking temperature T) and vanishing horizon area Ah, but with finite Ah/T ratio,the Extremal Vanishing Horizon (EVH) black holes. We study the near horizon limit of a four dimensional EVH black hole solution to a generic (gauged) Einstein-Maxwell dilaton theory and show that in the near horizon limit they develop a throat which is a pinching orbifold limit of AdS3. This is an extension of the well known result for extremal black holes the near horizon limit of which contains an AdS2 throat. We show that in the near EVH near horizon limit the pinching AdS3 factor turns to a pinching BTZ black hole and that this near horizon limit is indeed a decoupling limit. We argue that the pinching AdS3 or BTZ orbifold is resolved if the near horizon limit is accompanied by taking the 4d Newton constant G4 to zero such that the Bekenstein-Hawking entropy S = Ah/(4G4) remains finite. We propose that in this limit the near horizon EVH black h...

  15. Finite temperature effective action, AdS_5 black holes, and 1/N expansion

    CERN Document Server

    Alvarez-Gaumé, Luís; Liu, H; Wadia, S; Alvarez-Gaume, Luis; Gomez, Cesar; Liu, Hong; Wadia, Spenta

    2005-01-01

    We propose a phenomenological matrix model to study string theory in AdS_5 \\times S_5 in the canonical ensemble. The model reproduces all the known qualitative features of the theory. In particular, it gives a simple effective potential description of Euclidean black hole nucleation and the tunnelling between thermal AdS and the big black hole. It also has some interesting predictions. We find that there exists a critical temperature at which the Euclidean small black hole undergoes a Gross-Witten phase transition. We identify the phase transition with the Horowitz-Polchinski point where the black hole horizon size becomes comparable to the string scale. The appearance of the Hagedorn divergence of thermal AdS is due to the merger of saddle points corresponding to the Euclidean small black hole and thermal AdS. The merger can be described in terms of a cusp (A_3) catastrophe and divergences at the perturbative string level are smoothed out at finite string coupling using standard techniques of catastrophe the...

  16. Supersymmetric $AdS_6$ vacua in six-dimensional $N=(1,1)$ gauged supergravity

    CERN Document Server

    Karndumri, Parinya

    2016-01-01

    We study fully supersymmetric $AdS_6$ vacua of half-maxi\\-mal $N=(1,1)$ gauged supergravity in six space-time dimensions coupled to $n$ vector multiplets. We show that the existence of $AdS_6$ backgrounds requires that the gauge group is of the form $G'\\times G"\\subset SO(4,n)$ where $G'\\subset SO(3,m)$ and $G"\\subset SO(1,n-m)$. In the $AdS_6$ vacua this gauge group is broken to its maximal compact subgroup $SO(3)\\times H'\\times H"$ where $H'\\subset SO(m)$ and $H"\\subset SO(n-m)$. Furthermore, the $SO(3)$ factor is the R-symmetry gauged by three of the four graviphotons. We further show that the $AdS_6$ vacua have no moduli that preserve all supercharges. This is precisely in agreement with the absence of supersymmetric marginal deformations in holographically dual five-dimensional superconformal field theories.

  17. Smoothed Transitions in Higher Spin AdS Gravity

    CERN Document Server

    Banerjee, Shamik; Hellerman, Simeon; Hijano, Eliot; Lepage-Jutier, Arnaud; Maloney, Alexander; Shenker, Stephen

    2012-01-01

    We consider CFTs conjectured to be dual to higher spin theories of gravity in AdS_3 and AdS_4. Two dimensional CFTs with W_N symmetry are considered in the lambda=0 (k --> infinity) limit, where they are conjectured to be described by continuous orbifolds. The torus partition function is computed, using reasonable assumptions, and equals that of a free field theory. We find no phase transition at temperatures of order one; the usual Hawking-Page phase transition is removed by the highly degenerate light states associated with conical defect states in the bulk. Three dimensional Chern-Simons-matter CFTs with vector-like matter are considered on T^3, where the dynamics is described by an effective theory for the eigenvalues of the holonomies. Likewise, we find no evidence for a Hawking-Page phase transition at large level k.

  18. Born Global Firms: A Foreign Trade Related Study on Turkey

    Directory of Open Access Journals (Sweden)

    Aytaç GÖKMEN

    2013-11-01

    Full Text Available With the comprehensive advent in information and communication technologies and worldwide ease of transportation, the volume of international trade and business increased profoundly. Within this process, a Born Global Firm (BGF, right from its initiation, aims at creating competitive advantage by marketing a large volume of its products in various international markets by utilizing technological advances. Therefore, the rational behind the idea of BGF is to become an international firm in a short period of time and making international business affairs core of its business activities. Thus, the aim of this study is to review the concept of BGF theoretically and relate the issue to foreign trade affairs resting on significant sources related to the Turkish case mainly focusing on trade statistics as to review the potential development of BGFs in Turkey.

  19. A twin study of perfume-related respiratory symptoms

    DEFF Research Database (Denmark)

    Elberling, J; Lerbaek, A; Kyvik, K O

    2009-01-01

    Respiratory symptoms from environmental perfume exposure are main complaints in patients with multiple chemical sensitivities and often coincide with asthma and or eczema. In this population-based twin study we estimate the heritability of respiratory symptoms related to perfume and if co......-occurrences of the symptoms in asthma, atopic dermatitis, hand eczema or contact allergy are influenced by environmental or genetic factors common with these diseases. In total 4,128 twin individuals (82%) responded to a questionnaire. The heritability of respiratory symptoms related to perfume is 0.35, 95%CI 0.......14-0.54. Significant associations (psymptoms and asthma, atopic dermatitis, hand eczema or contact allergy are not attributable to shared genetic or shared environmental/familial factors, except possibly for atopic dermatitis where genetic pleiotropy with respiratory symptoms...

  20. N=2 supersymmetric sigma-models in AdS

    CERN Document Server

    Butter, Daniel

    2011-01-01

    We construct the most general N=2 supersymmetric nonlinear sigma-model in four-dimensional anti-de Sitter (AdS) space in terms of N=1 chiral superfields. The target space is shown to be a non-compact hyperkahler manifold restricted to possess a special Killing vector field. A remarkable property of the sigma-model constructed is that the algebra of OSp(2|4) transformations is closed off the mass shell.