WorldWideScience

Sample records for ads related studies

  1. Neutron cross section measurements at n-TOF for ADS related studies

    CERN Document Server

    Mastinu, P F; Aerts, G; Alvarez, H; Alvarez-Velarde, F; Andriamonje, Samuel A; Andrzejewski, J; Assimakopoulos, P A; Audouin, L; Badurek, G; Bustreo, N; Aumann, P; Beva, F; Berthoumieux, E; Calviño, F; Cano-Ott, D; Capote, R; Carillo de Albornoz, A; Cennini, P; Chepel, V; Chiaveri, Enrico; Colonna, N; Cortés, G; Couture, A; Cox, J; Dahlfors, M; David, S; Dillmann, I; Dolfini, R; Domingo-Pardo, C; Dridi, W; Durán, I; Eleftheriadis, C; Segura, M E; Ferrant, L; Ferrari, A; Ferreira-Marques, R; itzpatrick, L; Frais-Kölbl, H; Fujii, K; Furman, W; Guerrero, C; Gonçalves, I; Gallino, R; González-Romero, E M; Goverdovski, A; Gramegna, F; Griesmayer, E; Gunsing, F; Haas, B; Haight, R; Heil, M; Herrera-Martínez, A; Igashira, M; Isaev, S; Jericha, E; Kadi, Y; Käppeler, F K; Karamanis, D; Karadimos, D; Kerveno, M; Ketlerov, V; Köhler, P; Konovalov, V; Kossionides, E; Krticka, M; Lamboudis, C; Leeb, H; Lindote, A; Lopes, I; Lozano, M; Lukic, S; Marganiec, J; Marques, L; Marrone, S; Massimi, C; Mengoni, A; Milazzo, P M; Moreau, C; Mosconi, M; Neves, F; Oberhummer, Heinz; O'Brien, S; Oshima, M; Pancin, J; Papachristodoulou, C; Papadopoulos, C; Paradela, C; Patronis, N; Pavlik, A; Pavlopoulos, P; Perrot, L; Plag, R; Plompen, A; Plukis, A; Poch, A; Pretel, C; Quesada, J; Rauscher, T; Reifarth, R; Rosetti, M; Rubbia, Carlo; Rudolf, G; Rullhusen, P; Salgado, J; Sarchiapone, L; Savvidis, I; Stéphan, C; Tagliente, G; Taín, J L; Tassan-Got, L; Tavora, L; Terlizzi, R; Vannini, G; Vaz, P; Ventura, A; Villamarín, D; Vincente, M C; Vlachoudis, V; Vlastou, R; Voss, F; Walter, S; Wendler, H; Wiescherand, M; Wisshak, K

    2006-01-01

    A neutron Time-of-Flight facility (n_TOF) is available at CERN since 2001. The innovative features of the neutron beam, in particular the high instantaneous flux, the wide energy range, the high resolution and the low background, make this facility unique for measurements of neutron induced reactions relevant to the field of Emerging Nuclear Technologies, as well as to Nuclear Astrophysics and Fundamental Nuclear Physics. The scientific motivations that have led to the construction of this new facility are here presented. The main characteristics of the n_TOF neutron beam are described, together with the features of the experimental apparata used for cross-section measurements. The main results of the first measurement campaigns are presented. Preliminary results of capture cross-section measurements of minor actinides, important to ADS project for nuclear waste transmutation, are finally discussed.

  2. From the generalized uncertainty relations on fuzzy AdS2 to the Poincare geometry

    International Nuclear Information System (INIS)

    The positive and discrete unitary irreps of SU(1,1) are used to construct fuzzy (Euclidean) AdS2. Two different types of uncertainty relation involving the Weyl-Heisenberg and a weaker type are studied. It is shown that there are no generalized coherent states which simultaneously minimize the Weyl-Heisenberg uncertainty relations among three non-commuting embedding coordinates of the fuzzy AdS2. However, generalized squeezed states that simultaneously satisfy the three weaker uncertainty relations do exist, and reproduce some properties of the classical AdS2. Up to a common scaling factor in terms of the irrep label, the expectation values of the non-commuting coordinates over such states are described in the same manner as the classical AdS2, in terms of the Poincare coordinates. The expectation values on the fuzzy AdS2 tend to their corresponding values in the commutative limit. (orig.)

  3. Integrating a health-related-quality-of-life module within electronic health records: a comparative case study assessing value added

    Directory of Open Access Journals (Sweden)

    Shea Christopher M

    2012-03-01

    Full Text Available Abstract Background Health information technology (HIT applications that incorporate point-of-care use of health-related quality of life (HRQL assessments are believed to promote patient-centered interactions between seriously ill patients and physicians. However, it is unclear how willing primary care providers are to use such HRQL HIT applications. The specific aim of this study was to explore factors that providers consider when assessing the value added of an HRQL application for their geriatric patients. Methods Three case studies were developed using the following data sources: baseline surveys with providers and staff, observations of staff and patients, audio recordings of patient-provider interactions, and semi-structured interviews with providers and staff. Results The primary factors providers considered when assessing value added were whether the HRQL information from the module was (1 duplicative of information gathered via other means during the encounter; (2 specific enough to be useful and/or acted upon, and; (3 useful for enough patients to warrant time spent reviewing it for all geriatric patients. Secondary considerations included level of integration of the HRQL and EHR, impact on nursing workflow, and patient reluctance to provide HRQL information. Conclusions Health-related quality of life modules within electronic health record systems offer the potential benefit of improving patient centeredness and quality of care. However, the modules must provide benefits that are substantial and prominent in order for physicians to decide that they are worthwhile and sustainable. Implications of this study for future research include the identification of perceived "costs" as well as a foundation for operationalizing the concept of "usefulness" in the context of such modules. Finally, developers of these modules may need to make their products customizable for practices to account for variation in EHR capabilities and practice

  4. From the generalized uncertainty relations on fuzzy AdS 2 to the Poincaré geometry

    Science.gov (United States)

    Fakhri, H.; Hashemi, A.; Lotfizadeh, M.

    2012-03-01

    The positive and discrete unitary irreps of SU(1,1) are used to construct fuzzy (Euclidean) AdS 2. Two different types of uncertainty relation involving the Weyl-Heisenberg and a weaker type are studied. It is shown that there are no generalized coherent states which simultaneously minimize the Weyl-Heisenberg uncertainty relations among three non-commuting embedding coordinates of the fuzzy AdS 2. However, generalized squeezed states that simultaneously satisfy the three weaker uncertainty relations do exist, and reproduce some properties of the classical AdS 2. Up to a common scaling factor in terms of the irrep label, the expectation values of the non-commuting coordinates over such states are described in the same manner as the classical AdS 2, in terms of the Poincaré coordinates. The expectation values on the fuzzy AdS 2 tend to their corresponding values in the commutative limit.

  5. Comparative study of effects of bone marrow cell vs. Ad5-HGF administration via non infarct-related artery injection in myocardial infarction in swine

    Institute of Scientific and Technical Information of China (English)

    Liansheng Wang; Jun Huang; Zhijian Yang; Wei Wang; Dongchao Ma; Shunlin Xu; Yuqing Zhang; Fang Zhou; Bo Chen; Kejiang Cao

    2007-01-01

    Objective: To evaluate the effect of transplanting bone marrow-derived mesenchymal stem cells (BM-MSCs) or adenovirus5-hepatocyte growth factor(Ad5-HGF) via non-infarct-related artery injection in swine myocardial infarction models. Methods :BMMSCs were obtained from swine bone marrow and expanded in vitro to a purity of >50%. A myocardial infarction(MI) was created by ligating the distal left anterior descending artery in swine. Either BM-MSCs (5 × 106/ml) or Ad5-HGF (4 × 109 pfu) were transfused via the right coronary artery (non-infarcted artery) four weeks after MI. Gate-controled cardiac perfusion imaging was performed at the end of four and seven weeks after LAD ligation, to evaluate heart function and cardiac perfusion. Morphologic and histologic characteristics of the hearts were also studied. Results: (1)The gate-controlled cardiac perfusion imaging showed that the improvement in LVEF was greater in both treatment groups than in control group at the 4th weeks. (2)In both treatment groups, capillary density was significantly higher than that of control group (P < 0.05). Conclusion:BM-MSCs or Ad5-HGF transplantation via non-infarcted artery administration can stimulate angiogenesis and improve heart function, but there was no difference in therapeutic efficacy between BM-MSCs and Ad5-HGF.

  6. Relational Resources in Value Adding Webs

    DEFF Research Database (Denmark)

    Gretzinger, Susanne; Royer, Susanne

    2014-01-01

    The fact that the main source of value creation is rooted within networks raises the question of the impact of social capital on relational rents. The main objectives of this paper therefore are to investigate how value creation on the relational level of a cluster can be systematised to come...... to a better understanding of valuable resources. Empirically the study refers to a regional cluster in Southern Jutland in Denmark. We found that the horizontal actors in the cluster see the core of initiated cluster activities rather on the edge of their business activities but at the same time highlight...

  7. The activities of HPPA technology related to ADS in China

    CERN Document Server

    Guan Xia Ling; Ding Da Zhao; Fang Jia Xun; Fang Shou Xian; Fu Shin Ian; Guo, Z Y; Jiang Wei; Li Jie Quan; Luo Zi Hua; Ouyang Hua Fu; Peng Chao Hua; Xu Tao Guang; Xu Wen Wu; Yu Qi; Zhang Zong Hua; Zhao Sheng Chu

    2001-01-01

    High Power Proton Accelerator (HPPA) is being studied all over world for numerous applications, which includes the waste transmutation, spallation neutron source and material irradiation facilities. In China, a multi-purpose verification system as a first phase of Chinese ADS program consists of a low energy accelerator (150 MeV/3 mA proton linac) and a swimming pool light water sub-critical reactor. The activities of HPPA technology related to ADS in China, which includes the intense proton ECR source, the RFQ accelerator and some other technology of HPPA, are described

  8. Quantum statistical relation for black holes in nonlinear electrodynamics coupled to Einstein-Gauss-Bonnet AdS gravity

    International Nuclear Information System (INIS)

    We consider curvature-squared corrections to Einstein-Hilbert gravity action in the form of a Gauss-Bonnet term in D>4 dimensions. In this theory, we study the thermodynamics of charged static black holes with anti-de Sitter (AdS) asymptotics, and whose electric field is described by nonlinear electrodynamics. These objects have received considerable attention in recent literature on gravity/gauge dualities. It is well-known that, within the framework of anti-de Sitter/conformal field theory (AdS/CFT) correspondence, there exists a nonvanishing Casimir contribution to the internal energy of the system, manifested as the vacuum energy for global AdS spacetime in odd dimensions. Because of this reason, we derive a quantum statistical relation directly from the Euclidean action and not from the integration of the first law of thermodynamics. To this end, we employ a background-independent regularization scheme which consists, in addition to the bulk action, of counterterms that depend on both extrinsic and intrinsic curvatures of the boundary (Kounterterm series). This procedure results in a consistent inclusion of the vacuum energy and chemical potential in the thermodynamic description for Einstein-Gauss-Bonnet AdS gravity regardless of the explicit form of the nonlinear electrodynamics Lagrangian.

  9. Study of ADS-B Data Evaluation

    Institute of Scientific and Technical Information of China (English)

    ZHANG Jun; LIU Wei; ZHU Yanbo

    2011-01-01

    In western China,the terrain and meteorological conditions are so complex that it is not suitable to construct new radar stations.Automatic dependent surveillance-broadcast(ADS-B) is a totally new surveillance method,so before practically applied and operated in China,abundant tests and evaluations are necessary to validate the performance of ADS-B and guarantee the operational security.During the flight tests,we collect the data of radar,ADS-B and high accuracy position and compare the performance of ADS-B with radar based on high accuracy position.To solve the asynchronous problem among radar data,ADS-B data and real-time kinematic(RTK) data caused by different update rates,this article proposes the technique of synchronizing multi-surveil- lance data by extrapolating from the data of low update rate to high update rate according to velocity and heading.Meanwhile,because radar data,ADS-B data and RTK data are expressed in different coordinates and cannot be compared each other,this article provides a method to unifying the coordinates of multi-surveillance data.By the analysis and evaluation,we can conclude that the performance of ADS-B is better than radar.

  10. Analytical study on holographic superfluid in AdS soliton background

    Science.gov (United States)

    Lai, Chuyu; Pan, Qiyuan; Jing, Jiliang; Wang, Yongjiu

    2016-06-01

    We analytically study the holographic superfluid phase transition in the AdS soliton background by using the variational method for the Sturm-Liouville eigenvalue problem. By investigating the holographic s-wave and p-wave superfluid models in the probe limit, we observe that the spatial component of the gauge field will hinder the phase transition. Moreover, we note that, different from the AdS black hole spacetime, in the AdS soliton background the holographic superfluid phase transition always belongs to the second order and the critical exponent of the system takes the mean-field value in both s-wave and p-wave models. Our analytical results are found to be in good agreement with the numerical findings.

  11. Utilization of the BARC critical facility for ADS related experiments

    Indian Academy of Sciences (India)

    Rajeev Kumar; R Srivenkatesan

    2007-02-01

    The paper discusses the basic design of the critical facility, whose main purpose is the physics validation of AHWR. Apart from moderator level control, the facility will have shutdown systems based on shutoff rods and multiple ranges of neutron detection systems. In addition, it will have a flux mapping system based on 25 fission chambers, distributed in the core. We are planning to use this reactor for experiments with a suitable source to simulate an ADS system. Any desired sub-criticality can be achieved by adjusting the moderator level. Apart from perfecting our experimental techniques, in simple configurations, we intend to study the one-way coupled core in this facility. Preliminary calculations, employing a Monte Carlo code TRIPOLI, are presented.

  12. 17 CFR 240.17Ad-13 - Annual study and evaluation of internal accounting control.

    Science.gov (United States)

    2010-04-01

    ... internal accounting control. 240.17Ad-13 Section 240.17Ad-13 Commodity and Securities Exchanges SECURITIES... Company Rules § 240.17Ad-13 Annual study and evaluation of internal accounting control. (a) Accountant's... accountant concerning the transfer agent's system of internal accounting control and related procedures...

  13. From the generalized uncertainty relations on fuzzy AdS{sub 2} to the Poincare geometry

    Energy Technology Data Exchange (ETDEWEB)

    Fakhri, H. [University of Tabriz, Department of Theoretical Physics and Astrophysics, Faculty of Physics, P. O. Box 51666-16471, Tabriz (Iran, Islamic Republic of); Institute for Research in Fundamental Sciences (IPM), School of Physics, P. O. Box 19395-5531, Tehran (Iran, Islamic Republic of); Hashemi, A.; Lotfizadeh, M. [University of Tabriz, Department of Theoretical Physics and Astrophysics, Faculty of Physics, P. O. Box 51666-16471, Tabriz (Iran, Islamic Republic of)

    2012-03-15

    The positive and discrete unitary irreps of SU(1,1) are used to construct fuzzy (Euclidean) AdS{sub 2}. Two different types of uncertainty relation involving the Weyl-Heisenberg and a weaker type are studied. It is shown that there are no generalized coherent states which simultaneously minimize the Weyl-Heisenberg uncertainty relations among three non-commuting embedding coordinates of the fuzzy AdS{sub 2}. However, generalized squeezed states that simultaneously satisfy the three weaker uncertainty relations do exist, and reproduce some properties of the classical AdS{sub 2}. Up to a common scaling factor in terms of the irrep label, the expectation values of the non-commuting coordinates over such states are described in the same manner as the classical AdS{sub 2}, in terms of the Poincare coordinates. The expectation values on the fuzzy AdS{sub 2} tend to their corresponding values in the commutative limit. (orig.)

  14. Adding critical accounting voices to migration studies

    OpenAIRE

    Agyemang, Gloria; Lehman, Cheryl R.

    2013-01-01

    The field of migration study is continually evolving and frequently controversial. Although scholars in many disciplines have actively contributed to migration research, accounting scholars have been less actively engaged, despite migration’s use of concepts so closely aligned with accounting: costs, benefits, risk, and control. This paper considers how accounting researchers may contribute to the study of migration, highlighting the potential for critical researchers to re-define terrains o...

  15. CNRS-CEA study on ADS; Dossier CNRS-CEA ADS

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2003-07-01

    This document aims at presenting in a synthetic way the present day situation of the progress of technical feasibility studies of an accelerator driven system (ADS) for the transmutation of long-lived radioactive wastes. It aims also at defining the goals to be confirmed or to reach in order to consider the transmutation option in the national debate on radioactive wastes management: - present day evaluation results about the technical feasibility of an ADS: nuclear data, ADS reactor physics, accelerator, spallation target, nuclear fuels; - goals to be confirmed or to be reached: nuclear data, accelerator, spallation target, fuels, coolant, demonstration experiment; - planning of actions: TWG road-map, updated road-map. (J.S.)

  16. Delayed collapses of BECs in relation to AdS gravity

    CERN Document Server

    Biasi, Anxo F; Paredes, Angel

    2016-01-01

    We numerically investigate spherically symmetric collapses in the Gross-Pitaevskii equation with attractive nonlinearity in a harmonic potential. Even below threshold for direct collapse, the wave function bounces off from the origin and may eventually become singular after a number of oscillations in the trapping potential. This is reminiscent of the evolution of Einstein gravity sourced by a scalar field in Anti-de Sitter space where collapse corresponds to black hole formation. We carefully examine the long time evolution of the wave function for continuous families of initial states in order to sharpen out this coincidence which may bring new insights in both directions. On one hand, we comment on possible implications for the so-called Bosenova collapses in cold atom Bose-Einstein condensates. On the other hand, Gross-Pitaevskii provides a toy model to study the relevance of either the resonance conditions or the nonlinearity for the problem of Anti-de Sitter instability.

  17. An Experimental Study of Men's and Women's Personal Ads.

    Science.gov (United States)

    Strassberg, Donald S; English, Brittany L

    2015-11-01

    Personal ads have long served as a potentially rich source of information for social scientists regarding what women and men appear to be looking for in a partner and what they believe potential partners are looking for in them. Almost every study of this type has content analyzed existing personal ads in print media or, more recently, on the Internet. Many of the limits of this research approach were addressed in a study by Strassberg and Holty (2003) utilizing an experimental research design. Contrary to theory, prior research, and prediction, the most popular female seeking male (FSM) ad in that study was one in which the woman described herself as "financially independent, successful [and] ambitious," producing over 50 % more responses than the next most popular ad, describing the writer as "very attractive and slim." The present study replicated the Strassberg and Holty methodology, placing the same fictitious MSF and FSM personal ads using far more accessible Internet personal ad sites. Contrary to the previous finding, but consistent with evolutionary theories and social psychological experiments (e.g., Townsend & Wasserman, 1998), ads that presented the woman as attractive and the man as financially successful elicited the most interest. PMID:25388303

  18. Value added intellectual coefficient (VAIC): an empirical study

    OpenAIRE

    Mehrnaz Paknezhad; Ahmad Ahmadkhani

    2012-01-01

    There is no doubt that conventional accounting does not provide actual value of a firm since they only take into account the tangible assets. Intellectual capital provides a new concept for considering actual value of the assets, which helps calculate intangible values of the firm. In this paper, we use value added intellectual coefficient (VAIC) to measure the performance of a firm. The study investigates the relationship between intellectual capital and return on assets and value added for ...

  19. Health-related ad information and health motivation effects on product evaluations

    DEFF Research Database (Denmark)

    Chrysochou, Polymeros; Grunert, Klaus G

    2014-01-01

    in ads. Three types of healthrelated ad elements are distinguished: functional claims, process claims and health imagery. These elements were combined in mock ads and an online experiment was run to test the study hypotheses. Results show that health imagery has the largest impact on consumers' product...

  20. Revisit to Thermodynamic Relations in the AdS/CMT Models

    CERN Document Server

    Hyun, Seungjoon; Yi, Sang-Heon

    2016-01-01

    Motivated by the recent unified approach to the Smarr-like relation of AdS planar black holes in conjunction with the quasi-local formalism on conserved charges, we revisit the quantum statistical and thermodynamic relations of hairy AdS planar black holes. By extending the previous results, we identify the hairy contribution in the bulk and show that the holographic computation can be improved so that it is consistent with the bulk computation. We argue that the first law can be retained in its universal form while the relation between the on-shell renormalized Euclidean action and its free energy interpretation in gravity may be deformed to contain the hairy contribution in hairy AdS black holes.

  1. The Added Value of Study Abroad: Fostering a Global Citizenry

    Science.gov (United States)

    Tarrant, Michael A.; Rubin, Donald L.; Stoner, Lee

    2014-01-01

    Few studies have employed experimental designs adequate for documenting the value added of studying abroad; that is, learning outcomes above and beyond that which may be achieved in domestic or traditional campus-based courses. Using a pre-/posttest, two-by-two factor design of course location (study abroad vs. home campus) by course subject…

  2. Precortical Phase of Alzheimer's Disease (AD)-Related Tau Cytoskeletal Pathology.

    Science.gov (United States)

    Stratmann, Katharina; Heinsen, Helmut; Korf, Horst-Werner; Del Turco, Domenico; Ghebremedhin, Estifanos; Seidel, Kay; Bouzrou, Mohamed; Grinberg, Lea T; Bohl, Jürgen; Wharton, Stephen B; den Dunnen, Wilfred; Rüb, Udo

    2016-05-01

    Alzheimer's disease (AD) represents the most frequent progressive neuropsychiatric disorder worldwide leading to dementia. We systematically investigated the presence and extent of the AD-related cytoskeletal pathology in serial thick tissue sections through all subcortical brain nuclei that send efferent projections to the transentorhinal and entorhinal regions in three individuals with Braak and Braak AD stage 0 cortical cytoskeletal pathology and fourteen individuals with Braak and Braak AD stage I cortical cytoskeletal pathology by means of immunostainings with the anti-tau antibody AT8. These investigations revealed consistent AT8 immunoreactive tau cytoskeletal pathology in a subset of these subcortical nuclei in the Braak and Braak AD stage 0 individuals and in all of these subcortical nuclei in the Braak and Braak AD stage I individuals. The widespread affection of the subcortical nuclei in Braak and Braak AD stage I shows that the extent of the early subcortical tau cytoskeletal pathology has been considerably underestimated previously. In addition, our novel findings support the concept that subcortical nuclei become already affected during an early 'pre-cortical' evolutional phase before the first AD-related cytoskeletal changes occur in the mediobasal temporal lobe (i.e. allocortical transentorhinal and entorhinal regions). The very early involved subcortical brain regions may represent the origin of the AD-related tau cytoskeletal pathology, from where the neuronal cytoskeletal pathology takes an ascending course toward the secondarily affected allocortex and spreads transneuronally along anatomical pathways in predictable sequences. PMID:26193084

  3. A Study On OFDM In Mobile Ad Hoc Network

    Directory of Open Access Journals (Sweden)

    Malik Nasereldin Ahmed

    2012-06-01

    Full Text Available Orthogonal Frequency Division Multiplexing (OFDM is the physical layer in emerging wireless local area networks that are also being targeted for ad hoc networking. OFDM can be also exploited in ad hoc networks to improve the energy performance of mobile devices. It is important in wireless networks because it can be used adaptively in a dynamically changing channel. This study gives a detailed view about OFDM and how it is useful to increase the bandwidth. This paper also gives an idea about how OFDM can be a promising technology for high capacity wireless communication.

  4. Area functional relation for 5D-Gauss-Bonnet-AdS black hole

    Science.gov (United States)

    Pradhan, Parthapratim

    2016-08-01

    We present area (or entropy) functional relation for multi-horizons five dimensional (5D) Einstein-Maxwell-Gauss-Bonnet-AdS black hole. It has been observed by exact and explicit calculation that some complicated function of two or three horizons area is mass-independent whereas the entropy product relation is not mass-independent. We also study the local thermodynamic stability of this black hole. The phase transition occurs at certain condition. Smarr mass formula and first law of thermodynamics have been derived. This mass-independent relation suggests they could turn out to be an universal quantity and further helps us to understanding the nature of black hole entropy (both interior and exterior) at the microscopic level. In the "Appendix", we have derived the thermodynamic products for 5D Einstein-Maxwell-Gauss-Bonnet black hole with vanishing cosmological constant.

  5. Studies on Functional Yogurt with Added Inulin as Prebiotic Fiber

    Directory of Open Access Journals (Sweden)

    Mirela Jimborean

    2015-11-01

    Full Text Available Products that contain both probiotics and prebiotics are known as symbiotic, these products are able to modify the composition of the internal microflora, with the beneficial effects on the consumer's body. The objective followed in this study was the obtaining of probiotic yogurt in which inulin is added. The control consists in an organoleptic examination, a physicochemical examination and monitoring of the evolution of bifidobacteria. The results obtained showed a progressive evolution by adding inulin. The highest difference was recorded for yogurt type 3 with an addition of 3% inulin, the number of bifidobacteria increased with 1.04x109 cfu/g in only 7 days, reaching 1.30 x 109 cfu/g.

  6. Value added intellectual coefficient (VAIC: an empirical study

    Directory of Open Access Journals (Sweden)

    Mehrnaz Paknezhad

    2012-04-01

    Full Text Available There is no doubt that conventional accounting does not provide actual value of a firm since they only take into account the tangible assets. Intellectual capital provides a new concept for considering actual value of the assets, which helps calculate intangible values of the firm. In this paper, we use value added intellectual coefficient (VAIC to measure the performance of a firm. The study investigates the relationship between intellectual capital and return on assets and value added for three consecutive years between 2008 and 2010. The results indicate that there is no meaningful relationship between intellectual capital and return on assets for fiscal years of 2008 and 2009 but there is a meaningful relationship between these two items for the fiscal year of 2010 when . Our findings also indicate that there is no meaningful relationship between intellectual capital and value added for the years of 2008 and 2010 but there is a meaningful relationship between the items for the fiscal year of 2009. The results somewhat confirm the recently published results in the literature, which argues the use of VAIC for assessing the direct impact of IC on other financial factors.

  7. Iterating free-field AdS/CFT: higher spin partition function relations

    Science.gov (United States)

    Beccaria, Matteo; Tseytlin, Arkady A.

    2016-07-01

    We find a simple relation between a free higher spin partition function on the thermal quotient of {{AdS}}d+1 and the partition function of the associated d-dimensional conformal higher spin field defined on the thermal quotient of {{AdS}}d. Starting with a conformal higher spin field defined in {{AdS}}d, one may also associate to with another conformal field in d-1 dimensions, thus iterating AdS/CFT. We observe that in the case of d=4, this iteration leads to a trivial 3d higher spin conformal theory with parity-even non-local action: it describes a zero total number of dynamical degrees of freedom and the corresponding partition function is equal to 1.

  8. Studies on Scrap Tyre Added Concrete for Rigid Pavements

    Directory of Open Access Journals (Sweden)

    Eldhose C.

    2014-12-01

    Full Text Available Waste tyre treatment is now global threat. Waste tyre dumping, disposal of these materials or burning these tyres cause serious environmental and health problems. This paper investigate the wide range of physical and mechanical properties of concrete containing waste tyre aggregates and assess its suitability as a construction material. Waste tyres are powdered into fine particles of various sizes and are used to replace the fine aggregate used in concrete. The fine scrap tyre aggregate is added as 2%, 4%, 6%, 10%, and 12% increment to replace the fine aggregate. This study aims to investigate the optimal use of waste tyre aggregates as fine aggregate in concrete composite.

  9. AD/HD Health Related Quality of Life Questionnaire Completed by Children or Adolescents

    Science.gov (United States)

    Erickson, Deborah; Clarke, Simon; Kohn, Michael

    2010-01-01

    Assessing health-related quality of life (HQOL) for children or adolescents with attention-deficit/hyperactivity disorder (AD/HD) to corroborate a diagnosis and monitor treatment outcomes, is usually relegated to parent, teacher and physician observation of the child/adolescent. Allowing adults to act as proxy reporters for children/adolescents…

  10. Study of Confinement/Deconfinement Transition in AdS/QCD with Generalized Warp Factors

    Directory of Open Access Journals (Sweden)

    Shobhit Sachan

    2014-01-01

    Full Text Available We study analytical solutions of charged black holes and thermally charged AdS with generalized warped factors in Einstein-Maxwell-Dilaton system. We calculate Euclidean action for charged AdS and thermally charged AdS. The actions in both backgrounds are regularized by the method of background subtraction. The study of phase transition between charged black hole and thermally charged AdS gives an insight into the confinement/deconfinement transition. The plots of grand potential versus temperature and chemical potential versus transition temperature are obtained.

  11. Planning of ADS related R and D in the Russian Federation

    International Nuclear Information System (INIS)

    ADS oriented R and D were initiated in Russia by ITEP in close cooperation with LANL in early nineties. In October 1998 the Scientific Council of the Ministry of Russian Federation for Atomic Power (MINATOM) decided to develop a Program of ADS related R and D coordinated and partly financed by MINATOM. Experimental investigations of ADS parameters include critical assembly in ITEP for precision measurements of neutron and kinetic parameters of subcritical multiplicating systems driven by pulsed neutron D-T generator; fast-thermal 'neutron valved' blankets imitated at the BFS-1 facility (IPPE) coupled with microtron accelerator. BFS-1 and BFS-2 critical assemblies are used to investigate the transmutation of minor actinides (MA). Theoretical methods and related computer codes are developed for the calculations of physical and thermohydraulic parameters of ADS covering transition processes and emergency situations in thermal, fast and cascade (two-stage) multiplicating blankets; neutron yields and spectra for the targets of various geometries and structures irradiated by GeV protons and ions; heat release, beam moderation, gas production and radiation damages in the target and window beam materials. (author)

  12. The Guinea Pig as a Model for Sporadic Alzheimer's Disease (AD: The Impact of Cholesterol Intake on Expression of AD-Related Genes.

    Directory of Open Access Journals (Sweden)

    Mathew J Sharman

    Full Text Available We investigated the guinea pig, Cavia porcellus, as a model for Alzheimer's disease (AD, both in terms of the conservation of genes involved in AD and the regulatory responses of these to a known AD risk factor - high cholesterol intake. Unlike rats and mice, guinea pigs possess an Aβ peptide sequence identical to human Aβ. Consistent with the commonality between cardiovascular and AD risk factors in humans, we saw that a high cholesterol diet leads to up-regulation of BACE1 (β-secretase transcription and down-regulation of ADAM10 (α-secretase transcription which should increase release of Aβ from APP. Significantly, guinea pigs possess isoforms of AD-related genes found in humans but not present in mice or rats. For example, we discovered that the truncated PS2V isoform of human PSEN2, that is found at raised levels in AD brains and that increases γ-secretase activity and Aβ synthesis, is not uniquely human or aberrant as previously believed. We show that PS2V formation is up-regulated by hypoxia and a high-cholesterol diet while, consistent with observations in humans, Aβ concentrations are raised in some brain regions but not others. Also like humans, but unlike mice, the guinea pig gene encoding tau, MAPT, encodes isoforms with both three and four microtubule binding domains, and cholesterol alters the ratio of these isoforms. We conclude that AD-related genes are highly conserved and more similar to human than the rat or mouse. Guinea pigs represent a superior rodent model for analysis of the impact of dietary factors such as cholesterol on the regulation of AD-related genes.

  13. Bace1 activity in cerebrospinal fluid and its relation to markers of ad pathology

    NARCIS (Netherlands)

    Mulder, S.D.; Flier, W.M. van der; Verheijen, J.H.; Mulder, C.; Scheltens, P.; Blankenstein, M.A.; Hack, C.E.; Veerhuis, R.

    2010-01-01

    Several studies have shown that reduced amyloid-β 1-42 (Aβ {42}) and increased tau levels in cerebrospinal fluid (CSF) reflect increased Alzheimer's disease (AD) pathology in the brain. β-site APP cleaving enzyme (BACE1) is thought to be the major β-secretase involved in Aβ production in the brain,

  14. Modified dispersion relations and (A)dS Schwarzschild Black holes

    OpenAIRE

    Han, Xin; Li, Huarun; Ling, Yi

    2008-01-01

    In this paper we investigate the impact of modified dispersion relations (MDR) on (Anti)de Sitter-Schwarzschild black holes. In this context we find the temperature of black holes can be derived with important corrections. In particular given a specific MDR the temperature has a maximal value such that it can prevent black holes from total evaporation. The entropy of the (A)dS black holes is also obtained with a logarithmic correction.

  15. Study on Sinkhole Attacks in Wireless Ad hoc Networks

    Directory of Open Access Journals (Sweden)

    GAGANDEEP

    2012-06-01

    Full Text Available Wireless ad hoc network is a collection of wireless mobile nodes that dynamically self-organize in arbitrary and temporary network topologies. As compared to conventional network, wireless ad hocnetwork are more vulnerable to the security attacks. The nature and structure of wireless ad hoc network makes it very attractive to attackers, because there is no fixed infrastructure and administrativeapproach in it. “Sinkhole attack” is one of the severe attacks in this type of network; this makes trustable nodes to malicious nodes that result in loss of secure information. This paper focuses on sinkhole attacks on routing protocols such as DSR, AODV. To overcome the problems occur due to sinkhole we discuss about Security-aware routing (SAR which helps to reduce the impact of such attack.

  16. A Cluster Maintenance Algorithm Based on Relative Mobility for Mobile Ad Hoc Network Management

    Institute of Scientific and Technical Information of China (English)

    SHENZhong; CHANGYilin; ZHANGXin

    2005-01-01

    The dynamic topology of mobile ad hoc networks makes network management significantly more challenging than wireline networks. The traditional Client/Server (Manager/Agent) management paradigm could not work well in such a dynamic environment, while the hierarchical network management architecture based on clustering is more feasible. Although the movement of nodes makes the cluster structure changeable and introduces new challenges for network management, the mobility is a relative concept. A node with high relative mobility is more prone to unstable behavior than a node with less relative mobility, thus the relative mobility of a node can be used to predict future node behavior. This paper presents the cluster availability which provides a quantitative measurement of cluster stability. Furthermore, a cluster maintenance algorithm based on cluster availability is proposed. The simulation results show that, compared to the Minimum ID clustering algorithm, our algorithm successfully alleviates the influence caused by node mobility and make the network management more efficient.

  17. Rate of entorhinal and hippocampal atrophy in incipient and mild AD: Relation to memory function

    OpenAIRE

    Stoub, T.R.; Rogalski, E.J.; Leurgans, S.; Bennett, D. A.; deToledo-Morrell, L.

    2008-01-01

    In the present study, as part of a more extensive longitudinal investigation of the in vivo anatomical markers of early and incipient AD in our laboratory, three groups of elderly participants were followed with yearly clinical evaluations and high resolution MRI scans over a 6-year period (baseline and 5 years of follow-up). At baseline, participants consisted of: (1) 35 old subjects with no cognitive impairment (controls); (2) 33 participants with amnestic mild cognitive impairment (MCI); a...

  18. Giant magnon solution and dispersion relation in string theory in AdS_3 x S^3 x T^4 with mixed flux

    CERN Document Server

    Hoare, B; Tseytlin, A A

    2013-01-01

    We address the question about the exact form of the dispersion relation for light-cone string excitations in string theory in AdS3 x S3 x T4 with mixed R-R and NS-NS 3-form fluxes. The analogy with string theory in AdS5 x S5 suggests that in addition to the data provided by the perturbative near-BMN expansion and the symmetry algebra considerations there is also another source of information about the dispersion relation -- the semiclassical giant magnon solution. In earlier work in arXiv:1303.1037 and arXiv:1304.4099 it was found that the symmetry algebra constraints consistent with perturbative expansion do not completely determine the form of the dispersion relation. The aim of the present paper is to fix it by constructing a generalization of the known dyonic giant magnon soliton on S3 to the presence of a non-zero NS-NS flux described by a WZ term in the string action. We find that the angular momentum of this soliton gets shifted by a term linear in world-sheet momentum. We also discuss the symmetry alg...

  19. Structure and Function of Benzylsuccinate Synthase and Related Fumarate-Adding Glycyl Radical Enzymes.

    Science.gov (United States)

    Heider, Johann; Szaleniec, Maciej; Martins, Berta M; Seyhan, Deniz; Buckel, Wolfgang; Golding, Bernard T

    2016-01-01

    The pathway of anaerobic toluene degradation is initiated by a remarkable radical-type enantiospecific addition of the chemically inert methyl group to the double bond of a fumarate cosubstrate to yield (R)-benzylsuccinate as the first intermediate, as catalyzed by the glycyl radical enzyme benzylsuccinate synthase. In recent years, it has become clear that benzylsuccinate synthase is the prototype enzyme of a much larger family of fumarate-adding enzymes, which play important roles in the anaerobic metabolism of further aromatic and even aliphatic hydrocarbons. We present an overview on the biochemical properties of benzylsuccinate synthase, as well as its recently solved structure, and present the results of an initial structure-based modeling study on the reaction mechanism. Moreover, we compare the structure of benzylsuccinate synthase with those predicted for different clades of fumarate-adding enzymes, in particular the paralogous enzymes converting p-cresol, 2-methylnaphthalene or n-alkanes. PMID:26959246

  20. Attitudes Towards Ads and Age. A Study in Seniors

    Directory of Open Access Journals (Sweden)

    Marta M. Estrada

    2014-08-01

    Full Text Available Older adults make up one of the markets with the greatest potential in the future. It is essential that businesses take the diversity within this group into account, and perform segmentation in order to obtain a favorable attitude towards the ad. The potential for segmentation by chronological age has been called into question in recent years, with cognitive age emerging as the main alternative. This research aims to analyses the relationship between the variables of attitude towards the ad, attitude towards the brand and purchasing intention among older adults, noting the moderating effect of the joint use of chronological age and cognitive age on these items.  DOI: 10.5585/remark.v13i3.2725

  1. Heavy density liquid metal spallation target studies for Indian ADS programme

    Indian Academy of Sciences (India)

    P Sathamurthy; L M Gantayet; A K Ray

    2007-02-01

    Department of Atomic Energy, India has taken up the development of ADS in view of many attractive features like inherent safety, capability to transmute large quantities of nuclear waste, better utilization of thorium etc. A roadmap has been finalized for the development of ADS. One of the key components of the ADS is the spallation target. Considering the neutron yield, thermal-hydraulics and radiation damage issues, we are proposing to develop spallation target based on heavy density liquid metals like lead and lead-bismuth-eutectic (LBE). Both window and windowless target configurations are presently being studied. In view of the various advantages we are also studying liquid metal flow circulation based on gas lift mechanism. An R&D programme has been initiated to address various physics and technology issues of ADS target. Under this programme, mercury and LBE experimental facilities are presently being set up. Along with these facilities, computational tools related to spallation physics (FLUKA) and CFD are being developed, and the existing ones are utilized to design the entire target loop as well as sub-systems. In this presentation the details of these activities are presented.

  2. Heavy density liquid metal spallation target studies for Indian ADS programme

    Science.gov (United States)

    Satyamurthy, P.; Gantayet, L. M.; Ray, A. K.

    2007-02-01

    Department of Atomic Energy, India has taken up the development of ADS in view of many attractive features like inherent safety, capability to transmute large quantities of nuclear waste, better utilization of thorium etc. A roadmap has been finalized for the development of ADS. One of the key components of the ADS is the spallation target. Considering the neutron yield, thermal-hydraulics and radiation damage issues, we are proposing to develop spallation target based on heavy density liquid metals like lead and lead{bismuth{eutectic (LBE). Both window and windowless target configurations are presently being studied. In view of the various advantages we are also studying liquid metal flow circulation based on gas lift mechanism. An R&D programme has been initiated to address various physics and technology issues of ADS target. Under this programme, mercury and LBE experimental facilities are presently being set up. Along with these facilities, computational tools related to spallation physics (FLUKA) and CFD are being developed, and the existing ones are utilized to design the entire target loop as well as sub-systems. In this presentation the details of these activities are presented.

  3. Studies on urban vehicular ad-hoc networks

    CERN Document Server

    Zhu, Hongzi

    2013-01-01

    With the advancement of wireless technology, vehicular ad hoc networks (VANETs) are emerging as a promising approach to realizing 'smart cities' and addressing many important transportation problems such as road safety, efficiency, and convenience.This brief provides an introduction to the large trace data set collected from thousands of taxis and buses in Shanghai, the largest metropolis in China. It also presents the challenges, design issues, performance modeling and evaluation of a wide spectrum of VANET research topics, ranging from realistic vehicular mobility models and opportunistic ro

  4. A study on the preparation of value-added products from the nonmetallic minerals

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-12-01

    This report consists of 4 subjects. (1) preparation of value-added products for limestone : The purpose of this study is to develop the process of grade up by economical processes with low and/or middle grade of domestic limestone and of powder coating by dry base. In this year, first of all, we investigated the status of application utilize and related industries with the domestic limestone, and then being consideration with condition selected the adequate sample from Taeback, Uljin, Andong, Jungsun and Kumsan area. (2) development of value added technology of pyrophyllite ore : Considering the value added technology for pyrophyllite ore, the study was carried out for development of manufacturing technology to produce paint's filler from pyrophyllite ore reserved at Bunam mine in Cheongsong, Kyungsangbuk-do. The objective of the study is to develop a technology for not only creating an added value of pyrophyllite but also substituting the imported pyrophyllite product. (3) manufacturing technology of materials for fine chemical and electronic industry use : For use high electrically conductive film and advanced high functional solid lubricant, add new and advanced high functional propertied to fine graphite powder through surface modification with gas and organic materials. In this year, scale up test(30 l/batch) were carried out to stand firm the process of graphite surface control and modification for mass produce and to appraise characteristics of surface modified graphite powders. To arrange in order the test sample for actual apply in related company. (4) manufacturing technology of materials for fine chemical industry use (sericite, muscovite) : During the past three years, we studied on the processing technology and treatment process for recovery of concentrated sericite and muscovite, fine grinding characterization and classification of purified sericite and muscovite and the basic study of surface modification which are used as a source material of

  5. Simulation study for Mobile Ad hoc Networks Using DMAC Protocol

    Directory of Open Access Journals (Sweden)

    Vikas Sejwar

    2012-01-01

    Full Text Available This paper addresses the issue of deafness problem in Mobile Ad Hoc Networks (MANETs using directional antennas. Directional antennas arebeneficial for wireless ad hoc networks consisting of a collection of wireless hosts. A suitable Medium Access Control (MAC protocol must be designed to best utilize directional antennas. Deafness is caused whentwo nodes are in ongoing transmission and a third node (Deaf Node wants to communicate with one of that node. But it get no response because transmission of two nodes are in process. Though directional antennas offer better spatial reuse, but this problem can have a serious impact on network performance. A New DMAC (Directional Medium Access Control protocol uses flags in DNAV (Directional Network Allocation Vector tables to maintain information regarding the transmissionbetween the nodes in the network and their neighbor’s location. Two performance matrices have been used to show the impact of New DMAC algorithm on Deafness problem using simulator. These are RTS Failure Ratio and RTS Retransmission due to timeout

  6. A Provisional Study of ADS Within Turkic Accelerator Complex Project

    CERN Document Server

    Arik, M; Caliskan, A; Cetiner, M A; Sultansoy, S

    2012-01-01

    The Turkic Accelerator Complex (TAC) project has been developed with the support of the Turkish State Planning Organization by the collaboration of 10 Turkish universities. The complex is planned to have four main facilities, namely: SASE FEL Facility Based on 1 GeV Electron Linac, Third Generation Synchrotron Radiation Facility (SR) Based on 3.56 GeV Positron Synchrotron, Super-Charm Factory ($\\sqrt{s} = 3.77$ GeV) by colliding the electron beam coming from the linac with an energy of 1 GeV and positron beam coming through the positron ring with an energy of 3.56 GeV, GeV scale proton accelerator. Later has two-fold goal: Neutron Spallation Source (NSS) and ADS. The proton accelerator construction will have 3 MeV, 100 MeV, and 1 GeV phases. The technical design report is planned to be finished in 2013. Since Turkey has essential Thorium reserves the ADS becomes very attractive for our country as emerging energy technology.

  7. 基于Ad hoc网络监控系统研究%Study of monitoring system based on Ad hoc network

    Institute of Scientific and Technical Information of China (English)

    詹旭; 杜玲艳; 雷跃荣; 陈健陵

    2012-01-01

    In view of the safety of Ad hoc network and the study of Ad hoc network,a monitoring system based on Ad hoc network was designed.Also the evaluation method of network node trust value was proposed,which can effectively prevent the malicious node and ensure the security of Ad hoc network.%针对Ad hoc网络安全问题研究Ad hoc网络,设计一个Ad hoc网络监控系统,同时提出一种对入网节点进行信任值评估的方法,能有效地防止恶意节点出现,确保Ad hoc网络安全.

  8. Studies on the preparation of value-added products for industrial minerals

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-12-01

    This report consists of 2 subjects. 1) Studies on the preparation of value-added products for limestone: This study has investigated to raise to high grade by economical processes with low grade of domestic limestone. We investigated the status of application utilize and related industries with the domestic limestone, and then being consideration with condition selected the adequate sample from Andong, Jungsun and Kumsan area. Magnetic materials were involved in impurities of sample, so magnetic separation method was applied in elimination of the ferro- and para-magnetic materials, such as chlorite, muscovite, quartz, dolomite, magnetite, feldspar and so on. Investigation of flotation was undertaken to eliminate impurities from limestone crude ore and the tests were performed to get a optimum condition adding oleic acid as a promoter, sodium silicate and sodium carbonate as a conditioning agents and MIBC as a frother, while to float the sulfide minerals added amyl xanthate as a promoter, and sulfuric acid as a pH regulator. Selective crushing and classification methods were performed to eliminate impurities depends on the mineral properties and should be the selective crushing methods are very useful at the manufacturing factory of heavy calcium carbonate with the dry milling system. 2) A study on development of value added technology of pyrophyllite and dickite: Pyrophyllite and dickite have being utilized as refractories, ceramics, cement, fiber glass, paper, rubber, paints etc. However, there are not any domestic companies to produce fillers of pyrophyllite and dickite for plastic and rubber. Moreover, several kinds of fillers are imported every year with expensive price for plastic and rubber filler. This study has purpose to develop manufacturing technologies to produce fillers for plastic and rubber of pyrophyllite and dickite. The chemical and mineralogical properties of samples, the optimum grinding condition and device for producing plastic fillers and

  9. A Quantitative Study on How Internet Search Ads Generate Consumer Traffic to Advertisers' Website

    Directory of Open Access Journals (Sweden)

    Jungsun Son

    2011-06-01

    Full Text Available This study aims to measure the impact of these two variables on consumers' 'click-through' rates (the number of users that click on the ad compared to the number of times the ad is delivered. The result is as follows. First, search ads play a critical role in drawing consumers to advertisers' websites. Once search ads are placed, the number of visitors increased tenfold. Secondly, when search ads are keyed to highly-involved words such as 'IDC', 'hosting' and 'co-location', click-through rates significantly fluctuate according to the type of advertising message. In this case, consumers respond much more positively to ads highlighting credibility and product quality than to ads with emphasis on sales and events. Thirdly, the placement of search ads also matters. The ad placed first in the search list overpowers ads in the third or fifth place in terms of click-through rates. However, there was no significant difference of click-through rates between ads in the third place and ads in fifth. Lastly, when estimating which variable plays the bigger role in bringing traffic to advertisers' websites, consumers are more receptive to the substance of the advertising message than to its placement, under the circumstances of high involvement.

  10. Study Added of Waste Chicken Egg Shell in Soils

    Directory of Open Access Journals (Sweden)

    Keng Wong Irwan Lie

    2016-01-01

    Full Text Available Soil is the foundation of structure or construction that will receive the load transfer through to foundation. If the soil has a carrying capacity of small and cannot withstand the load transfer can result in the failure of construction. If the soil has a carrying capacity of small ground it is necessary to stabilize or improve the soil so that an increase in the carrying capacity of the land so that it can be used for construction. One material is commonly used for soil stabilization with the addition of lime. Waste chicken egg shell is waste that is still rarely used, the results of research [1], states that composition egg shell broadly consists of water (1,6% and dry material (98,4%. The total dry ingredients are there, in shell eggs contained mineral elements (95,1% and protein (3,3%. Based on the existing mineral composition, then the egg shells are composed of crystalline CaCO3 (98,43%, MgCO3 (0,84% and Ca3(PO42 (0,75%. This research was done by adding powdered chicken egg shell waste in clay with a composition of 5%, 7,5%, 10% and 14% with physical properties test and soil compaction test.

  11. Study of an ADS Loaded with Thorium and Reprocessed Fuel

    Directory of Open Access Journals (Sweden)

    Graiciany de Paula Barros

    2012-01-01

    Full Text Available Accelerator-driven systems (ADSs are investigated for long-lived fission product transmutation and fuel regeneration. The aim of this paper is to investigate the nuclear fuel evolution and the neutronic parameters of a lead-cooled accelerator-driven system used for fuel breeding. The fuel used in some fuel rods was T232hO2 for U233 production. In the other fuel rods was used a mixture based upon Pu-MA, removed from PWR-spent fuel, reprocessed by GANEX, and finally spiked with thorium or depleted uranium. The use of reprocessed fuel ensured the use of T232hO2 without the initial requirement of U233 enrichment. In this paper was used the Monte Carlo code MCNPX 2.6.0 that presents the depletion/burnup capability, combining an ADS source and kcode-mode (for criticality calculations. The multiplication factor (keff evolution, the neutron energy spectra in the core at BOL, and the nuclear fuel evolution during the burnup were evaluated. The results indicated that the combined use of T232hO2 and reprocessed fuel allowed U233 production without the initial requirement of U233 enrichment.

  12. Value Adding Management

    DEFF Research Database (Denmark)

    Jensen, Per Anker; Katchamart, Akarapong

    2011-01-01

    Purpose: To investigate how Facilities Management (FM) can add value and develop a management concept that can assist facilities managers in implementing value adding strategies and practices. Theory: The study is based on the management model for FM included in the European FM standards, recent...... theories on added value of FM and real estate and the related concept of Value Management from building projects. The study is related to the EuroFM research group on The Added Value of FM. Design/methodology/approach: The study outlines a preliminary theoretical based management concept, which...... the relevance of the basic concept and provides an important example of how Value Adding Management can be implemented and added value measured. Originality/value: The study develops a concept of Value Adding Management, which is new in FM literature. It is expected to increase the awareness of the impacts...

  13. Study on the Current Situation and Evolvement on Ad Hoc Network%Ad Hoc网络的研究现状与发展

    Institute of Scientific and Technical Information of China (English)

    李悦; 蔡振

    2012-01-01

    Ad Hoc networks as a way to temporarily speed automatic network of mobile communication technologyhas been moreattention to the experts, the current wireless Ad Hoc network is a focus of study. This article describes the characteristics of Ad Hoc Networks and applications, and the research situation.%Ad Hoc网络做为一种能够临时快速自动组网的移动通信技术越来越得到专家们的重视,目前Ad Hoc网络也是无线网络研究中的一个重点和热点。介绍了Ad Hoc网络的特点和应用以及Ad Hoc网络的研究状况。

  14. Localization on $AdS_2\\times S^1$

    CERN Document Server

    David, Justin R; Gupta, Rajesh Kumar; Narain, Kumar

    2016-01-01

    Conformal symmetry relates the metric on $AdS_2 \\times S^{1}$ to that of $S^3$. This implies that under a suitable choice of boundary conditions for fields on $AdS_2$ the partition function of conformal field theories on these spaces must agree which makes $AdS_2 \\times S^{1}$ a good testing ground to study localization on non-compact spaces. We study supersymmetry on $AdS_2\\times S^1$ and determine the localizing Lagrangian for ${\\cal N}=2$ supersymmetric Chern-Simons theory on $AdS_2\\times S^1$. We evaluate the partition function of ${\\cal N}=2$ supersymmetric Chern-Simons theory on $AdS_2 \\times S^1$ using localization, where the radius of $S^1$ is $q$ times that of $AdS_2$. With boundary conditions on $AdS_2\\times S^1$ which ensure that all the physical fields are normalizable and lie in the space of square integrable wave functions in $AdS_2$, the result for the partition function precisely agrees with that of the theory on the $q$-fold covering of $S^3$.

  15. Integration and relative value of biomarkers for prediction of MCI to AD progression: Spatial patterns of brain atrophy, cognitive scores, APOE genotype and CSF biomarkers

    Directory of Open Access Journals (Sweden)

    Xiao Da

    2014-01-01

    Full Text Available This study evaluates the individual, as well as relative and joint value of indices obtained from magnetic resonance imaging (MRI patterns of brain atrophy (quantified by the SPARE-AD index, cerebrospinal fluid (CSF biomarkers, APOE genotype, and cognitive performance (ADAS-Cog in progression from mild cognitive impairment (MCI to Alzheimer's disease (AD within a variable follow-up period up to 6 years, using data from the Alzheimer's Disease Neuroimaging Initiative-1 (ADNI-1. SPARE-AD was first established as a highly sensitive and specific MRI-marker of AD vs. cognitively normal (CN subjects (AUC = 0.98. Baseline predictive values of all aforementioned indices were then compared using survival analysis on 381 MCI subjects. SPARE-AD and ADAS-Cog were found to have similar predictive value, and their combination was significantly better than their individual performance. APOE genotype did not significantly improve prediction, although the combination of SPARE-AD, ADAS-Cog and APOE ε4 provided the highest hazard ratio estimates of 17.8 (last vs. first quartile. In a subset of 192 MCI patients who also had CSF biomarkers, the addition of Aβ1–42, t-tau, and p-tau181p to the previous model did not improve predictive value significantly over SPARE-AD and ADAS-Cog combined. Importantly, in amyloid-negative patients with MCI, SPARE-AD had high predictive power of clinical progression. Our findings suggest that SPARE-AD and ADAS-Cog in combination offer the highest predictive power of conversion from MCI to AD, which is improved, albeit not significantly, by APOE genotype. The finding that SPARE-AD in amyloid-negative MCI patients was predictive of clinical progression is not expected under the amyloid hypothesis and merits further investigation.

  16. Integration and relative value of biomarkers for prediction of MCI to AD progression: spatial patterns of brain atrophy, cognitive scores, APOE genotype and CSF biomarkers.

    Science.gov (United States)

    Da, Xiao; Toledo, Jon B; Zee, Jarcy; Wolk, David A; Xie, Sharon X; Ou, Yangming; Shacklett, Amanda; Parmpi, Paraskevi; Shaw, Leslie; Trojanowski, John Q; Davatzikos, Christos

    2014-01-01

    This study evaluates the individual, as well as relative and joint value of indices obtained from magnetic resonance imaging (MRI) patterns of brain atrophy (quantified by the SPARE-AD index), cerebrospinal fluid (CSF) biomarkers, APOE genotype, and cognitive performance (ADAS-Cog) in progression from mild cognitive impairment (MCI) to Alzheimer's disease (AD) within a variable follow-up period up to 6 years, using data from the Alzheimer's Disease Neuroimaging Initiative-1 (ADNI-1). SPARE-AD was first established as a highly sensitive and specific MRI-marker of AD vs. cognitively normal (CN) subjects (AUC = 0.98). Baseline predictive values of all aforementioned indices were then compared using survival analysis on 381 MCI subjects. SPARE-AD and ADAS-Cog were found to have similar predictive value, and their combination was significantly better than their individual performance. APOE genotype did not significantly improve prediction, although the combination of SPARE-AD, ADAS-Cog and APOE ε4 provided the highest hazard ratio estimates of 17.8 (last vs. first quartile). In a subset of 192 MCI patients who also had CSF biomarkers, the addition of Aβ1-42, t-tau, and p-tau181p to the previous model did not improve predictive value significantly over SPARE-AD and ADAS-Cog combined. Importantly, in amyloid-negative patients with MCI, SPARE-AD had high predictive power of clinical progression. Our findings suggest that SPARE-AD and ADAS-Cog in combination offer the highest predictive power of conversion from MCI to AD, which is improved, albeit not significantly, by APOE genotype. The finding that SPARE-AD in amyloid-negative MCI patients was predictive of clinical progression is not expected under the amyloid hypothesis and merits further investigation.

  17. Security Strategy study of Ad hoc Network%Ad hoc网络的安全对策初探

    Institute of Scientific and Technical Information of China (English)

    顾炜江

    2010-01-01

    无线网络的安全问题变得越来越重要,Ad hoc网络是一种特殊的多跳移动无线网络,具有广泛的应用场合.文中介绍了Ad hoc网络的基本概念、结构特点和路由协议,然后在探讨Ad hoc网络安全需求的基础上,分析了Ad hoc网络易于遭受的攻击,并集中讨论了Ad hoc网络的安全缺陷和安全威胁,提出了网络的安全策略.

  18. Study on ADS Pb (Pb/Bi) spallation target

    International Nuclear Information System (INIS)

    The neutron yield and double differential cross section of outgoing neutron produced in p+Pb spallation reaction up to 1.6 GeV have been investigated by some theoretical. Residual radioactivity, energy deposition and radiation damage of the Pb target were studied as well. A verification facility commented of a swimming pool reactor driven by a pulsed low energy high current accelerator (150-300 MeV/3mA) is planned in the next phase of our project. Pb-Bi eutectic is one of the options as the target material in the facility. In order to investigate the material compatibility and the thermohydraulics of Pb-Bi eutectic, a simplified small-scale loop is under designing. (author)

  19. Relating life cycle assessment indicators to gross value added for Dutch dairy farms

    International Nuclear Information System (INIS)

    Sustainable dairy production requires farms that are economically viable, environmentally sound and socially acceptable. A low environmental impact of milk production is not necessarily associated with an economically viable farm. To gain insight into a possible trade-off between economic and environmental sustainability, the relation between the environmental and economic indicators of dairy farms was quantified, and farm characteristics that influence this relation were identified. Economic and environmental indicators were quantified for 119 specialized dairy farms in 2005, based on data from the Dutch Farm Accountancy Data Network (FADN). Economic indicators used were: gross value added expressed per kg fat-and-protein-corrected milk (FPCM) or expressed per unit of labour, i.e. labour productivity. Environmental indicators used were: land use per kg FPCM, energy use per kg FPCM, global warming potential per kg FPCM, eutrophication and acidification potential per kg FPCM or per ha of land. Environmental indicators were deduced from a life cycle assessment. High labour productivity on dairy farms was associated with low on-farm energy use, total and on-farm land use, total and on-farm global warming potential, and total and off-farm acidification potential per kg FPCM. High labour productivity, however, was associated also with high on-farm eutrophication and acidification potential per hectare. From partial least squares regression analysis, it was concluded that relations between economic and environmental indicators were affected mainly by milk production per ha, annual milk production per cow, farm size, and amount of concentrates per kg FPCM. An increase in annual milk production per cow, for example, not only increased labour productivity, reduced energy use and global warming potential per kg FPCM but also, in the case of an unchanged stocking density, increased eutrophication and acidification per ha. To be economically and environmentally sustainable

  20. Bodacious Berry, Potency Wood and the Aging Monster: Gender and Age Relations in Anti-Aging Ads

    Science.gov (United States)

    Calasanti, Toni

    2007-01-01

    This paper situates age discrimination within a broader system of age relations that intersects with other inequalities, and then uses that framework to analyze internet advertisements for the anti-aging industry. Such ads reinforce age and gender relations by positing old people as worthwhile only to the extent that they look and act like those…

  1. Experimental and Theoretical Study of the Rotation of Si Ad-dimers on the Si(100) Surface

    DEFF Research Database (Denmark)

    Swartzentruber, B. S.; Smith, A. P.; Jonsson, Hannes

    1996-01-01

    Scanning tunneling microscopy measurements and first principles density functional theory calculations are used to study the rate of the rotational transition of Si ad-dimers on top of the surface dimer rows of Si(100). The rotation rate and the relative population of the two stable orientations ...... of the ad-dimers are measured as a function of the applied electric field to extract the zero-field behavior. The measured relative stability of the two configurations is used to test the accuracy of various functionals for density functional theory calculations....

  2. Simulation Based: Study and Analysis of Routing Protocol in Vehicular Ad-hoc Network Environment

    Directory of Open Access Journals (Sweden)

    Vaishali D. Khairnar

    2012-03-01

    Full Text Available A Vehicular Ad hoc Network (VANET consists of vehicles which communicate with each other and exchange data via wireless communication links available between the vehicles which are in communication ranges of vehicles to improve the road safety in city. The communication between vehicles is used to provide road safety, comfort and entertainment. The performance of communication depends on how better routing takes place in the network. Routing data between the source and destination vehicle depends on the routing protocols being used in vehicular ad-hoc network. In this simulation based study we investigated about different ad hoc routing protocols for vehicular ad-hoc network (VANET. The main goal of our study was to identify which ad hoc routing protocol has better performance in highly mobile environment of vehicular ad-hoc network. We have measured the performance of routing protocols using 802.11p in vehicular ad-hoc network in which we considered the scenario of city (i.e. Route between Nerul and Vashi where we have take 1200 different types of vehicles and checked their performance. Routing protocols are selected after the literature review. The selected protocols are then evaluated through simulation under 802.11p in terms of performance metrics (i.e PDR & E2E delay

  3. A study of suppression of vapor explosions by adding inversely soluble polymers

    International Nuclear Information System (INIS)

    The mechanism of suppression of vapor explosions by adding inversely soluble polymers in water are studied. The vapor explosion experiments and the cooling experiment of silver test piece are conducted. Polymetric solution, Poly (ethylene oxide : PEO), of concentrations from 0 to 500 wppm, whose viscosity relative to water ranges from 1.00 to 2.00, is used. No vapor explosion is observed in the polymer solution at a higher concentration than 200 wppm. Quench experiments of a silver test piece submerged in the polymer solution or water are performed in order to examine the stability of film boiling. The cause of suppression of the vapor film collapse is concluded to the precipitation of PEO as a gel around the vapor film. (author)

  4. SIMULATION STUDY OF BLACKHOLE ATTACK IN THE MOBILE AD HOC NETWORKS

    Directory of Open Access Journals (Sweden)

    SHEENU SHARMA

    2009-06-01

    Full Text Available A wireless ad hoc network is a temporary network set up by wireless nodes usually moving randomly and communicating without a network infrastructure. Due to security vulnerabilities of the routing protocols, however, wireless ad hoc networks may be unprotected against attacks by the malicious nodes. In this study we investigated the effects of Blackhole attacks on the network performance. We simulated Blackhole attacks in Qualnet Simulator and measured the packet loss in the network with and without a blackhole. The simulation is done on AODV (Ad hoc On Demand Distance Vector Routing Protocol. The network performance in the presence of a blackhole is reduced up to 26%.

  5. Chasing the effects of Pre-analytical Confounders - a Multicentre Study on CSF-AD biomarkers

    Directory of Open Access Journals (Sweden)

    Maria Joao Leitao

    2015-07-01

    Full Text Available Core cerebrospinal fluid (CSF biomarkers-Aβ42, Tau and pTau–have been recently incorporated in the revised criteria for Alzheimer’s disease (AD. However, their widespread clinical application lacks standardization. Pre-analytical sample handling and storage play an important role in the reliable measurement of these biomarkers across laboratories. In this study, we aim to surpass the efforts from previous studies, by employing a multicentre approach to assess the impact of less studied CSF pre-analytical confounders in AD-biomarkers quantification. Four different centres participated in this study and followed the same established protocol. CSF samples were analysed for three biomarkers (Aβ42, Tau and pTau and tested for different spinning conditions (temperature: Room temperature (RT vs. 4oC; speed: 500g vs. 2000g vs. 3000g, storage volume variations (25%, 50% and 75% of tube total volume as well as freezing-thaw cycles (up to 5 cyles. The influence of sample routine parameters, inter-centre variability and relative value of each biomarker (reported as normal/abnormal, was analysed. Centrifugation conditions did not influence biomarkers levels, except for samples with a high CSF total protein content, where either non centrifugation or centrifugation at RT, compared to 4ºC, led to higher Aβ42 levels. Reducing CSF storage volume from 75% to 50% of total tube capacity, decreased Aβ42 concentration (within analytical CV of the assay, whereas no change in Tau or pTau was observed. Moreover, the concentration of Tau and pTau appears to be stable up to 5 freeze-thaw cycles, whereas Aβ42 levels decrease if CSF is freeze-thawed more than 3 times. This systematic study reinforces the need for CSF centrifugation at 4ºC prior to storage and highlights the influence of storage conditions in Aβ42 levels. This study contributes to the establishment of harmonized standard operating procedures that will help reducing inter-lab variability of CSF-AD

  6. Studying Vehicle Movements on Highways and their Impact on Ad-Hoc Connectivity

    OpenAIRE

    Füßler, Holger; Torrent-Moreno, Marc; Krüger, Roland; Transier, Matthias; Hartenstein, Hannes; Effelsberg, Wolfgang

    2005-01-01

    While Mobile Ad-Hoc Networks are generally studied using a randomized node movement model such as the Random Way-Point model [8], Vehicular Ad-Hoc Networks deal with street-bound vehicles following a completely different movement pattern. This results - among other things - in a completely different connectivity situation and new challenges for data dissemination or routing/forwarding algorithms. Thus, researchers need a) suitable movement patterns for simulation, and b) a solid statistical u...

  7. Dressing phases of AdS3/CFT2

    CERN Document Server

    Borsato, Riccardo; Sfondrini, Alessandro; Stefanski, Bogdan; Torrielli, Alessandro

    2013-01-01

    We determine the all-loop dressing phases of the AdS3/CFT2 integrable system related to type IIB string theory on AdS3 x S3 x T4 by solving the recently found crossing relations and studying their singularity structure. The two resulting phases present a novel structure with respect to the ones appearing in AdS5/CFT4 and AdS4/CFT3. In the strongly-coupled regime, their leading order reduces to the universal Arutyunov-Frolov-Staudacher phase as expected. We also compute their sub-leading order and compare it with recent one-loop perturbative results, and co

  8. Dressing phases of AdS3/CFT2

    Science.gov (United States)

    Borsato, Riccardo; Ohlsson Sax, Olof; Sfondrini, Alessandro; Stefański, Bogdan, Jr.; Torrielli, Alessandro

    2013-09-01

    We determine the all-loop dressing phases of the AdS3/CFT2 integrable system related to type IIB string theory on AdS3×S3×T4 by solving the recently found crossing relations and studying their singularity structure. The two resulting phases present a novel structure with respect to the ones appearing in AdS5/CFT4 and AdS4/CFT3. In the strongly coupled regime, their leading order reduces to the universal Arutyunov-Frolov-Staudacher phase as expected. We also compute their subleading order and compare it with recent one-loop perturbative results and comment on their weak-coupling expansion.

  9. Extensive numerical study of a D-brane, anti-D-brane system in AdS 5 /CFT 4

    OpenAIRE

    Hegedűs, Árpád(MTA Lendület Holographic QFT Group, Wigner Research Centre, H-1525, Budapest 114, P.O.B. 49, Hungary)

    2015-01-01

    In this paper the hybrid-NLIE approach of [38] is extended to the ground state of a D-brane anti-D-brane system in AdS/CFT. The hybrid-NLIE equations presented in the paper are finite component alternatives of the previously proposed TBA equations and they admit an appropriate framework for the numerical investigation of the ground state of the problem. Straightforward numerical iterative methods fail to converge, thus new numerical methods are worked out to solve the equations. Our numerical...

  10. A high performance, ad-hoc, fuzzy query processing system for relational databases

    Science.gov (United States)

    Mansfield, William H., Jr.; Fleischman, Robert M.

    1992-01-01

    Database queries involving imprecise or fuzzy predicates are currently an evolving area of academic and industrial research. Such queries place severe stress on the indexing and I/O subsystems of conventional database environments since they involve the search of large numbers of records. The Datacycle architecture and research prototype is a database environment that uses filtering technology to perform an efficient, exhaustive search of an entire database. It has recently been modified to include fuzzy predicates in its query processing. The approach obviates the need for complex index structures, provides unlimited query throughput, permits the use of ad-hoc fuzzy membership functions, and provides a deterministic response time largely independent of query complexity and load. This paper describes the Datacycle prototype implementation of fuzzy queries and some recent performance results.

  11. Studies on the preparation of value-added products for limestone

    Energy Technology Data Exchange (ETDEWEB)

    Chae, Young Bae; Jeong, Soo Bok; Ko, Won Sik; Park, Je Shin; Oh, Jung Whan [Korea Institute of Geology Mining and Materials, Taejon (Korea, Republic of)

    1997-12-01

    Most of limestone in our country was consumed by the cement and iron/steel making industries and the amount of that was up to 72 million ton in 1996. Recently, importation of high grade limestone that have properties of high whiteness and grade are increased with diversification of chemical products and powder as various qualified filler, because high grade limestone are limited and of few deposit in our country. Therefore, the purpose of this study has investigated to raise to high grade by economical processes with low grade of domestic limestone. In this year, first of all, we investigated the status of application utilize and related industries with the domestic limestone, and then being consideration with condition selected the adequate sample from Andong, Jungsun and Kumsan area. Magnetic materials were involved in impurities of sample, so magnetic separation method was applied in elimination of the ferro-magnetic materials and para-magnetic materials, such as chlorite, muscovite, quartz, dolomite, magnetite, feldspar and so on. The limestone sample has many kinds of impurity. Investigation of flotation was undertaken to eliminate impurities from limestone crude ore and the tests were performed to get a optimum condition adding oleic acid as a promoter, sodium silicate and sodium carbonate as a conditioning agents and MIBC as a frother, while to float the sulfide minerals added amyl xanthate as a promoter, and sulfuric acid as a pH regulator. And most of the impurities involving in flotation sink contained such as quartz, chlorite, muscovite, feldspar, dolomite and so on. Selective crushing and classification methods were performed to eliminate impurities depends on the mineral properties and should be the selective crushing methods are very useful at the manufacturing factory of heavy calcium carbonate with the dry milling system. (author). 36 refs., 46 tabs., 33 figs.

  12. Association between alcohol consumption and diabetic retinopathy and visual acuity-the AdRem Study

    NARCIS (Netherlands)

    Lee, C. C.; Stolk, R. P.; Adler, A. I.; Patel, A.; Chalmers, J.; Neal, B.; Poulter, N.; Harrap, S.; Woodward, M.; Marre, M.; Grobbee, D. E.; Beulens, J. W.

    2010-01-01

    Aims We investigated the association between alcohol consumption and diabetic retinopathy and deterioration of visual acuity in individuals with Type 2 diabetes. Methods We conducted a cohort analysis of 1239 participants with Type 2 diabetes aged 55-81 years enrolled in the AdRem study, a sub-study

  13. Conical singularities in AdS space time

    International Nuclear Information System (INIS)

    Full text: In recent years, the study of conformal gauge theories from 10-D has been motivated by the AdSd+1/CFTd correspondence, first conjectured by J. Maldacena. The aim of this work is to consider the d = 4 case by analysing the configuration of the N coincident D3 branes. In this context, the work shows that there is a duality between type IIB string theory in AdS5 x S5 and N = 4 SU(N) Super Yang-Mills Theory in the IR. The AdS5/CFT4 correspondence brought also new approaches to the strong coupling problem in QCD. Nowadays, there is a whole line of works that focus on the low dimensional correspondence AdS4/CFT3, like the application to graphene and topological insulators, and the AdS3/CFT2 correspondence, related with the entanglement entropy. In this work, we consider the vortex configuration solution to the AdS4 and AdS3 space-time. The most important motivation is to discuss the boundary theory resulting from these solutions. We have examined a straightforward approach to a holographic computation of the graphene and entanglement entropy in the presence of the conical singularity. After this analysis, we consider the scalar field in the bulk in the presence of this metrics and work out the compactification modes. Taking the holographic point of view, we study and discuss the resulting Green function. (author)

  14. The added value of water footprint assessment for national water policy: a case study for Morocco.

    Directory of Open Access Journals (Sweden)

    Joep F Schyns

    Full Text Available A Water Footprint Assessment is carried out for Morocco, mapping the water footprint of different activities at river basin and monthly scale, distinguishing between surface- and groundwater. The paper aims to demonstrate the added value of detailed analysis of the human water footprint within a country and thorough assessment of the virtual water flows leaving and entering a country for formulating national water policy. Green, blue and grey water footprint estimates and virtual water flows are mainly derived from a previous grid-based (5 × 5 arc minute global study for the period 1996-2005. These estimates are placed in the context of monthly natural runoff and waste assimilation capacity per river basin derived from Moroccan data sources. The study finds that: (i evaporation from storage reservoirs is the second largest form of blue water consumption in Morocco, after irrigated crop production; (ii Morocco's water and land resources are mainly used to produce relatively low-value (in US$/m3 and US$/ha crops such as cereals, olives and almonds; (iii most of the virtual water export from Morocco relates to the export of products with a relatively low economic water productivity (in US$/m3; (iv blue water scarcity on a monthly scale is severe in all river basins and pressure on groundwater resources by abstractions and nitrate pollution is considerable in most basins; (v the estimated potential water savings by partial relocation of crops to basins where they consume less water and by reducing water footprints of crops down to benchmark levels are significant compared to demand reducing and supply increasing measures considered in Morocco's national water strategy.

  15. Adding constraints to predation through allometric relation of scats to consumption.

    Science.gov (United States)

    Chakrabarti, Stotra; Jhala, Yadvendradev V; Dutta, Sutirtha; Qureshi, Qamar; Kadivar, Riaz F; Rana, Vishwadipsinh J

    2016-05-01

    A thorough understanding of mechanisms of prey consumption by carnivores and the constraints on predation help us in evaluating the role of carnivores in an ecosystem. This is crucial in developing appropriate management strategies for their conservation and mitigating human-carnivore conflict. Current models on optimal foraging suggest that mammalian carnivores would profit most from killing the largest prey that they can subdue with minimal risk of injury to themselves. Wild carnivore diets are primarily estimated through analysis of their scats. Using extensive feeding experiments (n = 68) on a wide size range (4·5-130 kg) of obligate carnivores - lion, leopard, jungle cat and domestic cat, we parameterize biomass models that best relate consumption to scat production. We evaluate additional constraints of gut fill, prey digestibility and carcass utilization on carnivory that were hereto not considered in optimal foraging studies. Our results show that patterns of consumption to scat production against prey size are similar and asymptotic, contrary to established linear models, across these carnivores after accounting for the effect of carnivore size. This asymptotic, allometric relationship allowed us to develop a generalized model: biomass consumed per collectable scat/predator weight = 0·033-0·025exp(-4·284(prey weight/predator weight)) , which is applicable to all obligate carnivores to compute prey biomass consumed from scats. Our results also depict a relationship for prey digestibility which saturates at about 90% for prey larger than predator size. Carcass utilization declines exponentially with prey size. These mechanisms result in digestible biomass saturating at prey weights approximately equal to predator weight. Published literature on consumption by tropical carnivores that has relied on linear biomass models is substantially biased. We demonstrate the nature of these biases by correcting diets of tiger, lion and leopard in recent

  16. A Model of Adding Relations in Multi-levels to a Formal Organization Structure with Two Subordinates

    Science.gov (United States)

    Sawada, Kiyoshi; Amano, Kazuyuki

    2009-10-01

    This paper proposes a model of adding relations in multi-levels to a formal organization structure with two subordinates such that the communication of information between every member in the organization becomes the most efficient. When edges between every pair of nodes with the same depth in L (L = 1, 2, …, H) levels are added to a complete binary tree of height H, an optimal set of depths {N1, N2, …, NL} (H⩾N1>N2> …>NL⩾1) is obtained by maximizing the total shortening path length which is the sum of shortening lengths of shortest paths between every pair of all nodes in the complete binary tree. It is shown that {N1, N2, …, NL}* = {H, H-1, …, H-L+1}.

  17. Comparative study of Attacks on AODV-based Mobile Ad Hoc Networks

    Directory of Open Access Journals (Sweden)

    Ipsa De

    2011-01-01

    Full Text Available In recent years, the use of mobile ad hoc networks (MANETs has been widespread in many applications, The lack of infrastructures in MANETs makes the detection and control of security hazards allthe more difficult. The security issue is becoming a major concern and bottle neck in the application of MANET. In this paper, an attempt has been made to thoroughly study the blackhole attack which is one ofthe possible attacks in ad hoc networks in routing protocol AODV with possible solution to blackhole attack detection.

  18. Performance and Comparison of Multi-Hop Ad-Hoc Routing Protocols - Quantitative Study

    Directory of Open Access Journals (Sweden)

    Tamilarasan S

    2012-11-01

    Full Text Available Wireless ad-hoc network is emerging network and form temporary networks. Due to its spontaneous nature the topology is frequently changes. Protocols selection and set up routing between any pair of nodes are the primary goal design for any wireless network. Several protocols are proposed in Mobile Ad-hoc Network (MANET and selected protocol must provide best capability of data delivery and data integrity. In this paper, we are study and analysis the performance and characteristic of Ad-hoc On-demand Distance Vector (AODV, Dynamic Source Routing (DSR, Optimized Link State Routing (OLSR and Destination Sequenced Distance Vector (DSDV protocols using NS2 simulator. We are comparing the above said protocols based on the delay, throughput, control overhead and packet delivery ratio.

  19. Adding formoterol to budesonide in moderate asthma - health economic results from the FACET study

    NARCIS (Netherlands)

    Andersson, F; Stahl, E; Barnes, PJ; Lofdahl, CG; O'Byrne, PM; Pauwels, RA; Postma, DS; Tattersfield, AE; Ullman, A

    2001-01-01

    The FACET (Formoterol and Corticosteroid Establishing Therapy) study established that there is a clear clinical benefit in adding formoterol to budesonide therapy in patients who have persistent symptoms of asthma despite treatment with low to moderate doses of an inhaled corticosteroid. We combined

  20. AD FINEM IMPERII ROMANI! STUDIES IN HONOUR OF CORIOLAN H. OPREANU

    Directory of Open Access Journals (Sweden)

    Cristian Anton Gazdac

    2015-12-01

    Full Text Available AD FINEM IMPERII ROMANI! Studies in Honour of Coriolan H. Opreanu, editors: Cociș, S./ Lăzărescu, V.-A./ Gui, M./ Deac D.-A., Cluj-Napoca: Mega Publishing House, 2015, 390 pp. ISBN 9786065436008.

  1. Nucleation studies and characterization of potassium thiocyanate added KDP crystals grown by seed rotation technique

    Energy Technology Data Exchange (ETDEWEB)

    Dhanaraj, P.V. [Centre for Crystal Growth, SSN College of Engineering, Kalavakkam 603 110 (India); Rajesh, N.P., E-mail: rajeshnp@ssn.edu.i [Centre for Crystal Growth, SSN College of Engineering, Kalavakkam 603 110 (India); Mahadevan, C.K. [Physics Research Centre, S.T. Hindu College, Nagercoil 629 002 (India); Bhagavannarayana, G. [C.G.C. Section, National Physical Laboratory, New Delhi 110 012 (India)

    2009-08-01

    The effect of the addition of potassium thiocyanate on potassium dihydrogen phosphate (KDP) crystals, grown from aqueous solution by the temperature lowering method using a microcontroller based seed rotation technique has been studied. As part of nucleation studies, metastable zone width, induction period and crystal growth rate of additive added KDP are determined and analyzed with the pure system. Dielectric measurements were carried out on pure and doped crystals at various temperatures ranging from 313 to 423 K and compared. The crystalline perfection of the grown crystal was studied by the high resolution X-ray diffraction analysis. The crystal grown from additive added solution was subjected to structural, optical transmission, second harmonic generation and hardness studies and the effect of additive on pure system is investigated.

  2. Cardiovascular disease prediction: do pulmonary disease-related chest CT features have added value?

    Energy Technology Data Exchange (ETDEWEB)

    Jairam, Pushpa M. [University Medical Center Utrecht, Julius Center for Health Sciences and Primary Care, Utrecht (Netherlands); University Medical Center Utrecht, Department of Radiology, Utrecht (Netherlands); Jong, Pim A. de; Mali, Willem P.T.M. [University Medical Center Utrecht, Department of Radiology, Utrecht (Netherlands); Isgum, Ivana [University Medical Center Utrecht, Image Sciences Institute, Utrecht (Netherlands); Graaf, Yolanda van der [University Medical Center Utrecht, Julius Center for Health Sciences and Primary Care, Utrecht (Netherlands); Collaboration: PROVIDI study-group

    2015-06-01

    Certain pulmonary diseases are associated with cardiovascular disease (CVD). Therefore we investigated the incremental predictive value of pulmonary, mediastinal and pleural features over cardiovascular imaging findings. A total of 10,410 patients underwent diagnostic chest CT for non-cardiovascular indications. Using a case-cohort approach, we visually graded CTs from the cases and from an approximately 10 % random sample of the baseline cohort (n = 1,203) for cardiovascular, pulmonary, mediastinal and pleural findings. The incremental value of pulmonary disease-related CT findings above cardiovascular imaging findings in cardiovascular event risk prediction was quantified by comparing discrimination and reclassification. During a mean follow-up of 3.7 years (max. 7.0 years), 1,148 CVD events (cases) were identified. Addition of pulmonary, mediastinal and pleural features to a cardiovascular imaging findings-based prediction model led to marginal improvement of discrimination (increase in c-index from 0.72 (95 % CI 0.71-0.74) to 0.74 (95 % CI 0.72-0.75)) and reclassification measures (net reclassification index 6.5 % (p < 0.01)). Pulmonary, mediastinal and pleural features have limited predictive value in the identification of subjects at high risk of CVD events beyond cardiovascular findings on diagnostic chest CT scans. (orig.)

  3. Cardiovascular disease prediction: do pulmonary disease-related chest CT features have added value?

    International Nuclear Information System (INIS)

    Certain pulmonary diseases are associated with cardiovascular disease (CVD). Therefore we investigated the incremental predictive value of pulmonary, mediastinal and pleural features over cardiovascular imaging findings. A total of 10,410 patients underwent diagnostic chest CT for non-cardiovascular indications. Using a case-cohort approach, we visually graded CTs from the cases and from an approximately 10 % random sample of the baseline cohort (n = 1,203) for cardiovascular, pulmonary, mediastinal and pleural findings. The incremental value of pulmonary disease-related CT findings above cardiovascular imaging findings in cardiovascular event risk prediction was quantified by comparing discrimination and reclassification. During a mean follow-up of 3.7 years (max. 7.0 years), 1,148 CVD events (cases) were identified. Addition of pulmonary, mediastinal and pleural features to a cardiovascular imaging findings-based prediction model led to marginal improvement of discrimination (increase in c-index from 0.72 (95 % CI 0.71-0.74) to 0.74 (95 % CI 0.72-0.75)) and reclassification measures (net reclassification index 6.5 % (p < 0.01)). Pulmonary, mediastinal and pleural features have limited predictive value in the identification of subjects at high risk of CVD events beyond cardiovascular findings on diagnostic chest CT scans. (orig.)

  4. Study of micro piezoelectric vibration generator with added mass and capacitance suitable for broadband vibration

    Energy Technology Data Exchange (ETDEWEB)

    He, Qing, E-mail: hqng@163.com; Mao, Xinhua, E-mail: 30400414@qq.com; Chu, Dongliang, E-mail: 569256386@qq.com [School of Energy, Power and Mechanical Engineering, North China Electric Power University, Beijing 102206 (China)

    2015-07-15

    This study proposes an optimized frequency adjustment method that uses a micro-cantilever beam-based piezoelectric vibration generator based on a combination of added mass and capacitance. The most important concept of the proposed method is that the frequency adjustment process is divided into two steps: the first is a rough adjustment step that changes the size of the mass added at the end of cantilever to adjust the frequency in a large-scale and discontinuous manner; the second step is a continuous but short-range frequency adjustment via the adjustable added capacitance. Experimental results show that when the initial natural frequency of a micro piezoelectric vibration generator is 69.8 Hz, then this natural frequency can be adjusted to any value in the range from 54.2 Hz to 42.1 Hz using the combination of the added mass and the capacitance. This method simply and effectively matches a piezoelectric vibration generator’s natural frequency to the vibration source frequency.

  5. Study of micro piezoelectric vibration generator with added mass and capacitance suitable for broadband vibration

    Directory of Open Access Journals (Sweden)

    Qing He

    2015-07-01

    Full Text Available This study proposes an optimized frequency adjustment method that uses a micro-cantilever beam-based piezoelectric vibration generator based on a combination of added mass and capacitance. The most important concept of the proposed method is that the frequency adjustment process is divided into two steps: the first is a rough adjustment step that changes the size of the mass added at the end of cantilever to adjust the frequency in a large-scale and discontinuous manner; the second step is a continuous but short-range frequency adjustment via the adjustable added capacitance. Experimental results show that when the initial natural frequency of a micro piezoelectric vibration generator is 69.8 Hz, then this natural frequency can be adjusted to any value in the range from 54.2 Hz to 42.1 Hz using the combination of the added mass and the capacitance. This method simply and effectively matches a piezoelectric vibration generator’s natural frequency to the vibration source frequency.

  6. Utility of AD8 for Cognitive Impairment in a Chinese Physical Examination Population: A Preliminary Study

    Directory of Open Access Journals (Sweden)

    Yue Xie

    2014-01-01

    Full Text Available Objective. To investigate the utility of AD8 for cognitive impairment in a Chinese physical examination population. Methods. Military cadres who took routine physical examination in Chinese PLA General Hospital from Jan 1, 2013, to Dec 31, 2013, were subjected to AD8 scale. Individual information such as age, gender, and education was also collected. All data were analyzed by SPSS 19.0. Results. 1544 subjects were enrolled in this study with mean age 75.4 ± 10.6 years. The subjects who scored 0 to 8 of AD8 scale were 1015, 269, 120, 60, 30, 14, 19, 8, and 9, respectively. Corresponding proportions were 65.7%, 17.4%, 7.8%, 3.9%, 2.0%, 0.9%, 1.2%, 0.5%, and 0.6%, respectively. The endorsement prevalence of 8 questions was 5.6%, 9.2%, 6.6%, 9.2%, 4.8%, 4.5%, 8.9%, and 24.1%, respectively. The endorsement prevalence of question 8 was significantly higher than others (P<0.05. 260 subjects were scored equal to or greater than 2. The abnormal rate was 16.9%. All the participants were stratified into 9 groups by age; the prevalence of dementia was highly correlated with age (P<0.01. Conclusion. AD8 scale is a convenient and effective tool for cognitive screening in routine physical examination population.

  7. Study of micro piezoelectric vibration generator with added mass and capacitance suitable for broadband vibration

    International Nuclear Information System (INIS)

    This study proposes an optimized frequency adjustment method that uses a micro-cantilever beam-based piezoelectric vibration generator based on a combination of added mass and capacitance. The most important concept of the proposed method is that the frequency adjustment process is divided into two steps: the first is a rough adjustment step that changes the size of the mass added at the end of cantilever to adjust the frequency in a large-scale and discontinuous manner; the second step is a continuous but short-range frequency adjustment via the adjustable added capacitance. Experimental results show that when the initial natural frequency of a micro piezoelectric vibration generator is 69.8 Hz, then this natural frequency can be adjusted to any value in the range from 54.2 Hz to 42.1 Hz using the combination of the added mass and the capacitance. This method simply and effectively matches a piezoelectric vibration generator’s natural frequency to the vibration source frequency

  8. KNOWLEDGE MANAGEMENT via INFORMATION TECHNOLOGIES CASE STUDY QUALITY CONTROL PLANS IN SIEMENS A&D ET

    OpenAIRE

    MORALI, ASLI

    2006-01-01

    SUMMARY Title: Knowlege Management via Information Technologies, Case Study: Quality Control Plans In Siemens A&D ET Author: Asli Morali Supervisor: Anders Hederstierna Department: School of Management, Blekinge Institute of Technology Course: MBA thesis, 10 credits. Background and Problem Discussion: Efficient knowledge management becomes day by day a very critical issue for organizations by being considered as one of the most important competitive advantages. Globalization brings more c...

  9. BRST Quantization of String Theory in AdS(3)

    CERN Document Server

    Pakman, A

    2003-01-01

    We study the BRST quantization of bosonic and NSR strings propagating in AdS(3) x N backgrounds. The no-ghost theorem is proved using the Frenkel-Garland-Zuckerman method. Regular and spectrally-flowed representations of affine SL(2,R) appear on an equal footing. Possible generalizations to related curved backgrounds are discussed.

  10. Feasibility study for the assessment of the exposed dose with TENORM added in consumer products

    International Nuclear Information System (INIS)

    Consumer products including naturally occurring radioactive material have been distributed widely in human life. The potential hazard of the excessively added technically enhanced naturally occurring radioactive material (TENORM) in consumer products should be assessed. The aim of this study is to evaluate the organ equivalent dose and the annual effective dose with the usage of the TENORM added in paints. The activities of gammas emitted from natural radionuclides in the five types of paints were measured with the high-purity germanium detector, and the annual effective dose was assessed with the computational human phantom and the Monte Carlo method. The results show that uranium and thorium series were mainly measured over the five paints. Based on the exposure scenario of the paints in the room, the highest effective dose was evaluated as <1 mSv y-1 of the public dose limit. (authors)

  11. ADS National Programmes: China

    International Nuclear Information System (INIS)

    In China the conceptual study of an ADS concept which lasted for about five years ended in 1999. As one project of the National Basic Research Programme of China (973 Programme) in energy domain, which is sponsored by the China Ministry of Science and Technology (MOST), a five year programme of fundamental research of ADS physics and related technology was launched in 2000 and passed national review at the end of 2005. From 2007, another five year 973 Programme Key Technology Research of Accelerator Driven Subcritical System for Nuclear waste Transmutation started. The research activities were focused on HPPA physics and technology, reactor physics of external source driven subcritical assembly, nuclear data base and material study. For HPPA, a high current injector consisting of an ECR ion source, LEBT and an RFQ accelerating structure of 3.5 MeV has been built and were being improved. In reactor physics study, a series of neutron multiplication experimental study has been carrying out. The VENUS I facility has been constructed as the basic experimental platform for neutronics study in ADS blanket. VENUS I a zero power subcritical neutron multiplying assembly driven by external neutron produced by a pulsed neutron generator or 252Cf neutron source. The theoretical, experimental and simulation studies on nuclear data, material properties and nuclear fuel circulation related to ADS are carried out in order to provide the database for ADS system analysis. China Institute of Atomic Energy (CIAE), Institute of High Energy Physics (IHEP) and other Chinese institutes carried out the MOST project together. Besides CIAE, China Academy of Science (CAS) pays more and more attention to Advanced Nuclear Fuel Cycles (ANFC). A large programme of ANFC, including ADS and Th based nuclear fuel cycle, has been launched by CAS

  12. Application case study of AP1000 automatic depressurization system (ADS) for reliability evaluation by GO-FLOW methodology

    International Nuclear Information System (INIS)

    Highlights: • Discussion on reasons why AP1000 equipped with ADS system comparatively to PWR. • Clarification of full and partial depressurization of reactor coolant system by ADS system. • Application case study of four stages ADS system for reliability evaluation in LBLOCA. • GO-FLOW tool is capable to evaluate dynamic reliability of passive safety systems. • Calculated ADS reliability result significantly increased dynamic reliability of PXS. - Abstract: AP1000 nuclear power plant (NPP) utilized passive means for the safety systems to ensure its safety in events of transient or severe accidents. One of the unique safety systems of AP1000 to be compared with conventional PWR is the “four stages Automatic Depressurization System (ADS)”, and ADS system originally works as an active safety system. In the present study, authors first discussed the reasons of why four stages ADS system is added in AP1000 plant to be compared with conventional PWR in the aspect of reliability. And then explained the full and partial depressurization of RCS system by four stages ADS in events of transient and loss of coolant accidents (LOCAs). Lastly, the application case study of four stages ADS system of AP1000 has been conducted in the aspect of reliability evaluation of ADS system under postulated conditions of full RCS depressurization during large break loss of a coolant accident (LBLOCA) in one of the RCS cold legs. In this case study, the reliability evaluation is made by GO-FLOW methodology to determinate the influence of ADS system in dynamic reliability of passive core cooling system (PXS) of AP1000, i.e. what will happen if ADS system fails or successfully actuate. The GO-FLOW is success-oriented reliability analysis tool and is capable to evaluating the systems reliability/unavailability alternatively to Fault Tree Analysis (FTA) and Event Tree Analysis (ETA) tools. Under these specific conditions of LBLOCA, the GO-FLOW calculated reliability results indicated

  13. Studies on the preparation of value-added products for limestone

    Energy Technology Data Exchange (ETDEWEB)

    Chae, Young Bae; Jeong, Soo Bok; Ko, Won Sik; Chang, Byung Pyo [Korea Institute of Geology Mining and Materials, Taejon (Korea)

    1998-12-01

    Imports of high grade limestone and calcium carbonate powder that have properties of high whiteness and grade are increased with diversification of chemical products and powder as various qualified filler, because high grade limestone are limited or few deposited in our country. There are three kinds in the importation calcium carbonate powder that have properties of high whiteness over 95 deg., high purity and hydrophobic with fatty acid coating at the powder surface. This study is to develop the process of grade up by economical processes with low and/or middle grade of domestic limestone and of powder coating by dry base. We investigated the status of application utilize and related industries with the domestic limestone, and then being consideration with condition selected the adequate sample from Taeback, Uljin, Andong, Jungsun and Kumsan area. The limestone sample has many kinds of impurity. So, the method of preparation used in this experiment is Magnetic separation, Flotation, Selective crushing and Precision Classifying according the mineral properties. Magnetic separation method was applied in elimination of the ferro-magnetic materials and para-magnetic materials, such as chlorite, muscovite, quartz dolomite, magnetite, feldspar and so on. Flotation process was undertaken to eliminate of the small size impurities form limestone crude ore and the tests were performed to get a optimum condition adding oleic acid as a promoter, sodium silicate and sodium carbonate as a conditioning agents and MIBC as a frother and sulfuric acid as a pH regulator. Selective crushing and classification methods were performed for eliminated impurities depends on the mineral properties and should be the selective crushing methods on the mineral properties and should be the selective crushing methods are very useful at the manufacturing process of heavy calcium carbonate with the dry milling system. In the heavy calcium carbonate powder coating experiments, A contact angle of

  14. Polarised black holes in AdS

    Science.gov (United States)

    Costa, Miguel S.; Greenspan, Lauren; Oliveira, Miguel; Penedones, João; Santos, Jorge E.

    2016-06-01

    We consider solutions in Einstein-Maxwell theory with a negative cosmological constant that asymptote to global AdS 4 with conformal boundary {S}2× {{{R}}}t. At the sphere at infinity we turn on a space-dependent electrostatic potential, which does not destroy the asymptotic AdS behaviour. For simplicity we focus on the case of a dipolar electrostatic potential. We find two new geometries: (i) an AdS soliton that includes the full backreaction of the electric field on the AdS geometry; (ii) a polarised neutral black hole that is deformed by the electric field, accumulating opposite charges in each hemisphere. For both geometries we study boundary data such as the charge density and the stress tensor. For the black hole we also study the horizon charge density and area, and further verify a Smarr formula. Then we consider this system at finite temperature and compute the Gibbs free energy for both AdS soliton and black hole phases. The corresponding phase diagram generalizes the Hawking-Page phase transition. The AdS soliton dominates the low temperature phase and the black hole the high temperature phase, with a critical temperature that decreases as the external electric field increases. Finally, we consider the simple case of a free charged scalar field on {S}2× {{{R}}}t with conformal coupling. For a field in the SU(N ) adjoint representation we compare the phase diagram with the above gravitational system.

  15. Risk Analyses and Studies on ADS-B System%ADS-B系统的原理分析与风险研究

    Institute of Scientific and Technical Information of China (English)

    胡飞

    2011-01-01

    ADS-B技术是下一代空中交通管制技术的重要组成部分,与传统雷达技术相比,它具有可靠性高、成本低等优点.本文简要介绍了ADS-B的基本概念,并以基于UAT数据链的ADS-B系统为例,对ADS-B系统的原理进行了分析.同时,指出了ADS-B系统运行过程中存在的系统风险.

  16. Dilatometric studies of Y2W3O12 with added Al2O3

    Indian Academy of Sciences (India)

    S Sumithra; A M Umarji

    2003-10-01

    Y2W3O12 exhibits negative thermal expansion along the three crystallographic directions due to the transverse thermal vibrations perpendicular to the Y-O-W linkage. It is highly hygroscopic and forms a trihydrate structure at room temperature. Dilatometric studies of Y2W3O12 show large thermal expansion hysteresis due to large grain size and a large initial positive thermal expansion due to the removal of water molecules. Al2O3 has been added to Y2W3O12 up to 10 wt% in an attempt to overcome the hygroscopicity and reduce the particle size and thereby the thermal expansion hysteresis. Thermo gravimetric, dilatometric and electron microscopic studies are presented to support these observations.

  17. Chasing the Effects of Pre-Analytical Confounders - A Multicenter Study on CSF-AD Biomarkers

    DEFF Research Database (Denmark)

    Leitão, Maria João; Baldeiras, Inês; Herukka, Sanna-Kaisa;

    2015-01-01

    INTRODUCTION: Core cerebrospinal fluid (CSF) biomarkers - Aβ42, Tau, and phosphorylated Tau (pTau) - have been recently incorporated in the revised criteria for Alzheimer's disease (AD). However, their widespread clinical application lacks standardization. Pre-analytical sample handling and storage....... METHODS: Four different centers participated in this study and followed the same established protocol. CSF samples were analyzed for three biomarkers (Aβ42, Tau, and pTau) and tested for different spinning conditions [temperature: room temperature (RT) vs. 4°C; speed: 500 vs. 2000 vs. 3000 g], storage...... of the assay), whereas no change in Tau or pTau was observed. Moreover, the concentration of Tau and pTau appears to be stable up to five freeze-thaw cycles, whereas Aβ42 levels decrease if CSF is freeze-thawed more than three times. CONCLUSION: This systematic study reinforces the need for CSF centrifugation...

  18. Charge Carrier Relaxation Study in Glass-Added Barium Titanate Ceramics Using Thermally Stimulated Depolarization Current

    Science.gov (United States)

    Zhang, Qian; Zhang, Yong; Liu, Xiaolin; Song, Xiaozhen; Zhu, Jia; Baturin, Ivan

    2016-08-01

    The depolarization process of glass-added barium titanate (BaTiO3) ceramics with two different glass concentrations was investigated using a thermally stimulated depolarization current (TSDC) technique. The TSDC spectra of the glass-added BaTiO3 ceramics show three peaks. The first sharp peak near the Curie temperature is due to pyroelectric current associated with ferroelectric-paraelectric phase transition. The middle temperature peak at about 200°C showed no dependence on the depolarization current peak position in the polarization field, and the activation energies of this peak were between 0.43 eV and 0.55 eV, which are attributed to the behavior of defect dipoles related to oxygen vacancies within the BaTiO3 grains. Moreover, the high temperature peak at around 300°C indicated that the depolarization current peak position depends on the polarization temperature and decreases with increasing polarization field. The activation energy of this high temperature peak was between 0.78 eV and 0.98 eV, which is similar to the activation energy for the motion of oxygen vacancies in perovskite oxides. The high temperature peak could be attributed to the migration of oxygen vacancies across grain boundaries. In this work we developed a model in which oxygen vacancies that originated from the defect within grains migrated from the anode to the cathode and some were trapped at the grain boundaries. It is presented here and successfully interprets the appearance and behavior of these peaks.

  19. Experimental study on grain and pore growth of Niobia-added UO2 pellets

    International Nuclear Information System (INIS)

    An experimental study on niobia-added UO2 had been done with aid of x-ray diffraction and metallography. It was observed that Nb5+ ions were very difficult to occupy UO2 only at the sample with y = 0.01 (where y=Nb/(Nb+U) atomic ratio). The second, second phase appeared at the samples with larger y. It was preferable that the rapid grain and pore growth is based on the theory expressing that occupation of Nb5+ ions UO2 crystal produces oxygen interstitial that then active grain and intergranular pore growth. It was known also that second phase containing uranium and niobium with low melting point (lower than 1390oC was formed at the samples with large y. The second phase melted during sintering and created rounded grains in the pellets

  20. Brain glucose metabolism in the early and specific diagnosis of Alzheimer's disease. FDG-PET studies in MCI and AD

    Energy Technology Data Exchange (ETDEWEB)

    Mosconi, Lisa [University of Florence, Department of Clinical Pathophysiology, Nuclear Medicine Unit (Italy); University School of Medicine, Center for Brain Health, MHL400, Department of Psychiatry New York, New York, NY (United States)

    2005-04-01

    The demographics of aging suggest a great need for the early diagnosis of dementia and the development of preventive strategies. Neuropathology and structural MRI studies have pointed to the medial temporal lobe (MTL) as the brain region earliest affected in Alzheimer's disease (AD). MRI findings provide strong evidence that in mild cognitive impairments (MCI), AD-related volume losses can be reproducibly detected in the hippocampus, the entorhinal cortex (EC) and, to a lesser extent, the parahippocampal gyrus; they also indicate that lateral temporal lobe changes are becoming increasingly useful in predicting the transition to dementia. Fluoro-2-deoxy-D-glucose positron emission tomography (FDG-PET) imaging has revealed glucose metabolic reductions in the parieto-temporal, frontal and posterior cingulate cortices to be the hallmark of AD. Overall, the pattern of cortical metabolic changes has been useful for the prediction of future AD as well as in distinguishing AD from other neurodegenerative diseases. FDG-PET on average achieves 90% sensitivity in identifying AD, although specificity in differentiating AD from other dementias is lower. Moreover, recent MRI-guided FDG-PET studies have shown that MTL hypometabolism is the most specific and sensitive measure for the identification of MCI, while the utility of cortical deficits is controversial. This review highlights cross-sectional, prediction and longitudinal FDG-PET studies and attempts to put into perspective the value of FDG-PET in diagnosing AD-like changes, particularly at an early stage, and in providing diagnostic specificity. The examination of MTL structures, which has so far been exclusive to MRI protocols, is then examined as a possible strategy to improve diagnostic specificity. All told, there is considerable promise that early and specific diagnosis is feasible through a combination of imaging modalities. (orig.)

  1. Ad hoc网络入侵检测技术的分析与研究%Study on Intrusion Detection Technology in Ad hoc Network

    Institute of Scientific and Technical Information of China (English)

    李华平

    2010-01-01

    随着Ad hoc网络的发展,无线网络安全问题愈加突出.由于移动Ad hoc网络与有线网络存在很大差别,针对有线网络开发的入侵检铡系统很难适用于移动Ad hoc网络.文章分析了移动Ad hoc网络中入侵检测所面临的挑战,对现有的几种典型Ad hoc网络入侵检测方案进行了综合的比较和研究.对移动Ad hoc中入侵检测技术的选择和下一步的研究方向提出了建议.

  2. Thinking Relationally about Studying "Up"

    Science.gov (United States)

    Stich, Amy E.; Colyar, Julia E.

    2015-01-01

    In this paper, the authors argue that despite a resurgence of elite studies, the majority of existing scholarship works to reify and legitimize social inequality through its language and method. In particular, the authors utilize Pierre Bourdieu's concept of relational thinking to review and critique contemporary research on elite education and…

  3. Hairy AdS Solitons

    CERN Document Server

    Anabalon, Andres; Choque, David

    2016-01-01

    We construct exact hairy AdS soliton solutions in Einstein-dilaton gravity theory. We discuss the role of these solutions for the existence of first order phase transitions for planar hairy black holes within these theories.

  4. 移动Ad Hoc网络的入侵检测研究%Study on Intrusion Detection in Wireless Ad Hoc Network

    Institute of Scientific and Technical Information of China (English)

    刘鲁西; 王志坚

    2005-01-01

    移动Ad Hoc网络是一种特殊的移动网络.目前的入侵检测技术不再适用于这种新的环境.本文在分析Ad Hoc网络的特点和当前的入侵检测技术后,给出了一种适合于Ad Hoc网络的入侵检测系统的结构.

  5. Study on the Current Situation and Evolvement on Ad Hoc Network%Ad Hoc网络的研究现状与发展

    Institute of Scientific and Technical Information of China (English)

    李悦; 蔡振

    2012-01-01

    Ad Hoc网络做为一种能够临时快速自动组网的移动通信技术越来越得到专家们的重视,目前Ad Hoc网络也是无线网络研究中的一个重点和热点.介绍了Ad Hoc网络的特点和应用以及Ad Hoc网络的研究状况.

  6. A Study of Mobile Ad Hoc Network Management Architecture%移动Ad hoc网络管理架构研究

    Institute of Scientific and Technical Information of China (English)

    耿哲; 徐晓宇

    2005-01-01

    在介绍移动Ad hoc网络特定管理要求的基础上,分析了SNMP/ANMP、Guerrilla和PBNM三种Ad hoc网络管理架构的机制和特点.研究表明管理框架应适应Ad hoc网络动态拓扑、带宽受限和节点能力有限等特点,而分布式、自适应和智能化的网络管理是未来Ad hoc网络管理发展的方向.

  7. Value-Added Dairy Products from Grass-Based Dairy Farms: A Case Study in Vermont

    Science.gov (United States)

    Wang, Qingbin; Parsons, Robert; Colby, Jennifer; Castle, Jeffrey

    2016-01-01

    On-farm processing of value-added dairy products can be a way for small dairy farms to diversify production and increase revenue. This article examines characteristics of three groups of Vermont farmers who have grass-based dairy farms--those producing value-added dairy products, those interested in such products, and those not interested in such…

  8. Polarised Black Holes in AdS

    CERN Document Server

    Costa, Miguel S; Oliveira, Miguel; Penedones, João; Santos, Jorge E

    2015-01-01

    We consider solutions in Einstein-Maxwell theory with a negative cosmological constant that asymptote to global $AdS_{4}$ with conformal boundary $S^{2}\\times\\mathbb{R}_{t}$. At the sphere at infinity we turn on a space-dependent electrostatic potential, which does not destroy the asymptotic $AdS$ behaviour. For simplicity we focus on the case of a dipolar electrostatic potential. We find two new geometries: (i) an $AdS$ soliton that includes the full backreaction of the electric field on the $AdS$ geometry; (ii) a polarised neutral black hole that is deformed by the electric field, accumulating opposite charges in each hemisphere. For both geometries we study boundary data such as the charge density and the stress tensor. For the black hole we also study the horizon charge density and area, and further verify a Smarr formula. Then we consider this system at finite temperature and compute the Gibbs free energy for both $AdS$ soliton and black hole phases. The corresponding phase diagram generalizes the Hawkin...

  9. Baby Skyrmions in AdS

    OpenAIRE

    Elliot-Ripley, Matthew; Winyard, Thomas

    2015-01-01

    We study the baby Skyrme model in a pure AdS background without a mass term. The tail decays and scalings of massless radial solutions are demonstrated to take a similar form to those of the massive flat space model, with the AdS curvature playing a similar role to the flat space pion mass. We also numerically find minimal energy solutions for a range of higher topological charges and find that they form concentric ring-like solutions. Popcorn transitions (named in analogy with studies of toy...

  10. Defects in higher-dimensional quantum field theory. Relations to AdS/CFT-correspondence and Kondo lattices

    Energy Technology Data Exchange (ETDEWEB)

    Schmidt, R.

    2007-03-15

    The present work is addressed to defects and boundaries in quantum field theory considering the application to AdS/CFT correspondence. We examine interactions of fermions with spins localised on these boundaries. Therefore, an algebra method is emphasised adding reflection and transmission terms to the canonical quantisation prescription. This method has already been applied to bosons in two space-time dimensions before. We show the possibilities of such reflection-transmission algebras in two, three, and four dimensions. We compare with models of solid state physics as well as with the conformal field theory approach to the Kondo effect. Furthermore, we discuss ansatzes of extensions to lattice structures. (orig.)

  11. The Study of Routing Strategies in Vehicular Ad- Hoc Network to Enhance Security

    OpenAIRE

    Parveen Kumar

    2012-01-01

    In VANET, or Intelligent Vehicular Ad-HocNetworking, defines an intelligent way of usingVehicular Networking. In VANET integrates onmultiple ad-hoc networking technologies such as WIFIIEEE 802.11p, WAVE IEEE 1609, WIMAX IEEE802.16, Bluetooth, IRA, and ZIGBEE for easy,accurate, effective and simple communication betweenvehicles on dynamic mobility. Effective measuressuch as media communication between vehicles canbe enabled as well as methods to track the automotivevehicles. In VANET helps in ...

  12. Hedonic and utilitarian Ad attributes in relation to advertising effectiveness - The role of consumer involvement and the context of tablet devices

    OpenAIRE

    Lehto, Sarianne

    2013-01-01

    OBJECTIVE OF THE STUDY: Previous marketing research on the relationship between consumer involvement and hedonic and utilitarian dimension has mostly concentrated on products and brands, rather than advertising attributes. Furthermore, advertising effectiveness has often been assessed from a single perspective, such as attitude toward the ad. Therefore this thesis is focused on the relationship between consumer involvement and hedonic and utilitarian ad attributes, and on how these are li...

  13. Study on the Improvement of Ad Hoc Network Routing Protocol AODV Efficient%高效的Ad Hoc网络AODV改进路由协议研究

    Institute of Scientific and Technical Information of China (English)

    陆彩霞

    2015-01-01

    Ad Hoc网络是一个自治系统,有临时多跳的特点,目前应用广泛,是当前研究热点之一.因为Ad Hoc网络拓扑结构变化频繁,本文对AODV路由协议进行了改进,研究出R_EAODV路由协议.%Ad Hoc network is a multi hop temporary autonomous system, has the characteristics of wide application, at present, is one of the hottest research topics. Because the Ad Hoc network topology changes frequently, this paper presents an improved AODV routing protocol, R_EAODV routing protocol research.

  14. Value-Added Services in Third-Party Logistics : A study from the TPL providers’ perspective about value-added service development, driving forces and barriers

    OpenAIRE

    Atkacuna, Ilze; Furlan, Karolina

    2009-01-01

    Competition in the logistics service industry has constantly increased over the last decades which has lead to the traditional services offered by third-party logistics (TPL) providers becoming commodities and no longer offering attractive profit margins. When the company’s core product becomes a commodity, the company’s performance of supplementary services becomes vital for competitive advantage. The term “value-added service” is defined as a service adding extra feature, form or functions ...

  15. A Study on New Pochonka Published in A.D. 1792

    Science.gov (United States)

    Ahn, Sang-Hyeon

    2009-12-01

    New Pochonka published in the eighteenth century of the Choson dynasty was composed of star-charts based on the new observations made by Jesuits in China and songs corrected a little bit from previous version of Pochonka. The asterisms in the previous Pochonka are listed in the same order to that in the Song dynasty's literature; while the asterisms in the new Pochonka are listed in accordance with Pu-tien-ko published in China after the Ming dynasty. The Chinese-style twelve-equatorial-section system is adopted in the new Pochonka, while in its song is adopted the zodiac system, which can be seen in the star-charts of previous version of Pochonka. The asterisms belonging to three or four neighboring lunar-mansions are drawn in one chart. Each chart covers asterisms not belonging to a certain range of right ascension, but to a certain lunar mansion. We estimate the forming era of the new Pochonka from the following facts; that the Ling-Tai-I-Hsiang-Chih was used to make charts and footnotes whose archetype can be found in the Chinese literature around A.D. 1700, that these Chinese books were imported into Choson in A.D. 1709, that the naming taboo to the emperor Khang-Hsi was used, that the order of Shen-Hsiu (參宿) was transposed with Tshui-Hsiu (자宿), and that the new Pochonka was substituted for the old version when the rules of Royal Astronomical Bureau was reformed in A.D. 1791. In conclusion, the parent sources of the charts and footnotes of the new Pochonka might be imported from the Ching dynasty around 1709 A.D. to form the new Pochonka between A.D. 1709 and A.D. 1791, and finally to be published in A.D. 1792. We discuss the possible future works to make a firm conclusion.

  16. Mobile Ad Hoc Networks: A Comparative Study of QoS Routing Protocols

    CERN Document Server

    Gangwar, Sanjeev; Kumar, Krishan

    2012-01-01

    This Article presents a thorough overview of QoS routing metrics, resources and factors affecting performance of QoS routing protocols. The relative strength, weakness, and applicability of existing QoS routing protocols are also studied and compared. QoS routing protocols are classified according to the QoS metrics used type of QoS guarantee assured.

  17. Study of Impact of Mobile Ad hoc Networking and its Future Applications

    Directory of Open Access Journals (Sweden)

    Ashema Hasti

    2012-01-01

    Full Text Available Today, many people carry numerous portable devices, such as laptops, mobile phones, PDAs and mp3 players, for use in their professional and private lives. For the most part, these devices are used separately-that is, their applications do not interact. Imagine, however, if they could interact directly: participants at a meeting could share documents or presentations; all communication could automatically be routed through the wireless corporate campus network. These examples of spontaneous, ad hoc wireless communication between devices might be loosely defined as a scheme, often referred to as ad hoc networking, which allows devices to establish communication, anytime and anywhere without the aid of a central infrastructure. This paper describes the concept of mobile ad hoc networking (MANET and points out some of its applications that can be envisioned for future. Also, the paper presents two of the technical challenges MANET poses, which include Geocasting and QoS.

  18. Value-added Applications of Libraries’ E-resources: A Case Study of Citation Analysis System

    Directory of Open Access Journals (Sweden)

    黃明居、吳東陽 Ming-Jiu Hwang,Tung-Yang Wu

    2014-04-01

    Full Text Available The libraries now still play as the role of information provider without effectively aggregate inforrmations to knowledge based on users’ requirement, though the budget of electronic resources increasing yearly. For example, the aggregative search of library resources just shorten the timeusers attach the electronic resources without providing real knowledge. This research proposed ageneral value-added model of electronic resources during the process building the citation analysissystem. With the model, the library would be offer some value-added enhancement, even knowledgeprovider furthermore, based on the typical knowledge from aggregation of electronic resources inthe library. pp. 66-81

  19. The FLUKA study of the secondary particles fluence in the AD-Antiproton Decelerator target area

    CERN Document Server

    Calviani, M

    2014-01-01

    In this paper we present Monte Carlo FLUKA simulations [1, 2] carried out to investigate the secondary particles fluence emerging from the antiproton production target and their spatial distribution in the AD target area. The detailed quantitative analysis has been performed for different positions along the magnet dog-leg as well as after the main collimator. These results allow tuning the position of the new beam current transformers (BCT) in the target area, in order to have a precise pulse-by-pulse evaluation of the intensity of negative particles injected in the AD-ring before the deceleration phase.

  20. Reconstruction of the western Pacific warm pool SST since 1644 AD and its relation to precipitation over East China

    Institute of Scientific and Technical Information of China (English)

    ZHANG ZiYin; GONG DaoYi; HE XueZhao; GUO Dong; FENG ShengHui

    2009-01-01

    Based on coral proxies we reconstructed the western Pacific warm pool sea surface temperature (SST) since 1644 AD.High-frequency reconstructions are based on eight high-pass filtered coral series and raw reconstructions are derived from eight unfiltered coral series,respectively.Validation and comparison with other SST/temperature series show that the reconstructed warm pool SST is highly reliable.The leading periods of warm pool SST are ~2.1,~2.3,~2.9,~3.6,~3.8,and 80.7-year during the last ~360 years.The warm pool SST exhibits some obvious long-term trends:an upward trend of 0.04℃ per century for the period of 1644-1825,while a decreasing trend of 0.24℃ per century for the period of 1826-1885,and then a remarkable warming trend of 0.28℃ per century taking place between 1886 and 2006.Especially,the SST shows the strongest trend of 0.67℃ increase per century during the last 50 years,a warming unprecedented since 1644 AD.On interannual timescale,the connections between ENSO and the warm pool SST are robust during the reconstruction period.There are significant correlations between the warm pool SST and summer precipitation of the Yellow River basin and Huaihe River basin;the correlation coefficients are-0.44 in reconstruction period (1880-1949 AD) and -0.46 in instrumental period (1950-2005 AD) respectively.This relationship is also found between flooddrought index and the warm pool SST during the past 360 years,and their correlation coefficients are -0.20 in reconstruction period and -0.46 in instrumental period respectively,significant at the 0.01 level.On interdecadal timescale,this connection is more robust,and the correlation coefficient of the low-pass filtered components is -0.42 during the whole period (1644-2000 AD).When the warm pool is warmer than normal,the precipitation is usually below the normal in the Yellow River and Huaihe River basin.On the contrary,when the warm pool is colder than the normal,there may be more precipitation

  1. Reconstruction of the western Pacific warm pool SST since 1644 AD and its relation to precipitation over East China

    Institute of Scientific and Technical Information of China (English)

    2009-01-01

    Based on coral proxies we reconstructed the western Pacific warm pool sea surface temperature (SST) since 1644 AD. High-frequency reconstructions are based on eight high-pass filtered coral series and raw reconstructions are derived from eight unfiltered coral series, respectively. Validation and comparison with other SST/temperature series show that the reconstructed warm pool SST is highly reliable. The leading periods of warm pool SST are ~2.1, ~2.3, ~2.9, ~3.6, ~3.8, and 80.7-year during the last ~360 years. The warm pool SST exhibits some obvious long-term trends: an upward trend of 0.04℃ per century for the period of 1644―1825, while a decreasing trend of 0.24℃ per century for the period of 1826―1885, and then a remarkable warming trend of 0.28℃ per century taking place between 1886 and 2006. Especially, the SST shows the strongest trend of 0.67℃ increase per century during the last 50 years, a warming unprecedented since 1644 AD. On interannual timescale, the connections between ENSO and the warm pool SST are robust during the reconstruction period. There are significant corre- lations between the warm pool SST and summer precipitation of the Yellow River basin and Huaihe River basin; the correlation coefficients are -0.44 in reconstruction period (1880―1949 AD) and -0.46 in instrumental period (1950―2005 AD) respectively. This relationship is also found between flooddrought index and the warm pool SST during the past 360 years, and their correlation coefficients are -0.20 in reconstruction period and-0.46 in instrumental period respectively, significant at the 0.01 level. On interdecadal timescale, this connection is more robust, and the correlation coefficient of the low-pass filtered components is -0.42 during the whole period (1644―2000 AD). When the warm pool is warmer than normal, the precipitation is usually below the normal in the Yellow River and Huaihe River basin. On the contrary, when the warm pool is colder than the normal

  2. Added Sugars

    Science.gov (United States)

    ... Restaurant Deciphering the Menu Ordering Your Meal Eating Fast Food Dining Out Tips by Cuisine Physical Activity Fitness ... Learn more about reading food labels . Limit your consumption of foods with high amounts of added sugars, ...

  3. Design Study of Full Scale Accelerator Driven System (ADS, for Transmuting High Level Waste of MA/Pu

    Directory of Open Access Journals (Sweden)

    Marsodi

    2008-07-01

    Full Text Available The ADS system used in this study consisting of a high intensity proton linear accelerator, a spallation target, and a sub-critical reactor core. The Pb-Bi spallation target is bombarded by high intensity protons coming from the accelerator. The fast neutrons generated from the spallation reaction were used to drive the sub-critical reactor core. In this ADS system, the neutron source is in the center of reactor core region, so that the neutron distribution was concentrated in the center of core region. In this case, the B/T of MA/Pu could be performed effectively in the center of core region. The neutron energy in the outer region of reactor core was decreased due to the moderation of fuel and coolant materials. Such condition gives a chance to perform Burning and/or Transmutation of LLFPs.The basic parameters of this system are shown in the form of neutronic design, neutron spectrum and B/T rate, including other aspects related to the safety operation system. Furthermore, the analysis of the ADS system was accomplished using ATRAS computer code of the Japan Atomic Energy Research Institute, JAERI[1]. Due to the complexity of the reactor calculation codes, the author has carried out only those calculations needed for analyzing the neutronics system and some parameters related to the safety system. Design study of the transmutation system was a full-scale power level system of 657.53 MWt sub-critical reactor for an accelerator-driven transmutation system. The liquid Pb-Bi was used together as the spallation target materials and coolant of the system, because of some advantages of Pb-Bi in the system concerning the comparison with the sodium coolant. Moreover, they have a possibility to achieve a hard neutron energy spectrum, avoid a positive void reactivity coefficient, allow much lower system operating temperatures, and are favorable for safety in the event of coolant leakage. The multiplication factor of sub-critical core design was adjusted

  4. The Added Value of Water Footprint Assessment for National Water Policy: A Case Study for Morocco

    NARCIS (Netherlands)

    Schyns, Joep F.; Hoekstra, Arjen Y.

    2014-01-01

    A Water Footprint Assessment is carried out for Morocco, mapping the water footprint of different activities at river basin and monthly scale, distinguishing between surface- and groundwater. The paper aims to demonstrate the added value of detailed analysis of the human water footprint within a cou

  5. Diffractive deep inelastic scattering in an AdS/CFT inspired model: A phenomenological study

    International Nuclear Information System (INIS)

    The analytical treatment of the nonperturbative QCD dynamics is one of the main open questions of the strong interactions. Currently, it is only possible to get some qualitative information about this regime considering other QCD-like theories, as, for example, the N=4 super Yang-Mills theory, where one can perform calculations in the nonperturbative limit of large 't Hooft coupling using the anti-de Sitter space/conformal field theory (AdS/CFT). Recently, the high energy scattering amplitude was calculated in the AdS/CFT approach, applied to deep-inelastic scattering and confronted with the F2 HERA data. In this work we extend the nonperturbative AdS/CFT inspired model for diffractive processes and compare its predictions with a perturbative approach based on the Balitsky-Kovchegov equation. We demonstrate that the AdS/CFT inspired model is not able to describe the current F2D(3) HERA data and predicts a similar behavior to that from the Balitsky-Kovchegov equation in the range 10-7 P -4. At smaller values of xP the diffractive structure function is predicted to be energy independent.

  6. Vallue-added tax fraud within the European Union : pilot study

    NARCIS (Netherlands)

    Aronowitz, A.A.; Laagland, D.C.G.; Paulides, G.

    1995-01-01

    This research project, to a certain degree, aims at filling the knowledge gap concerning organized business crime by highlighting one specific phenomenon, that of cross-border Vallue-Added Tax (VAT) fraud within the European Union. Insight is to be provided into: a) the effectiveness of the present

  7. Value added analysis and its distribution: a study on BOVESPA-listed banks using ANOVA

    Directory of Open Access Journals (Sweden)

    Leonardo José Seixas Pinto

    2013-05-01

    Full Text Available The value added generated by the financial institutions listed on BOVESPA and its distribution in the years between 2007 to 2011 are the subject of this research which shows how banks divided his wealth with the people, government, third parties and shareholders. Through the use of ANOVA test average in the companies that took part in this research concluded that: (a the average value added of foreign banks differs from national banks. (b The remuneration policy of equity foreign banks differs from national banks. (c The policy of distribution of value added to employees of foreign banks Santander and HSBC differs from the other banks. (d Taxes paid to the government have equal means with the exception of Santander. (e Although curious, Banco Itau and Banco do Brazil is equal in all analyzes in the distribution of value added since it is a private and one public. It appears this way a policy unequal distribution of wealth generation and foreign banks compared with the national public and private banks.

  8. How is an ideal satiating yogurt described? A case study with added-protein yogurts

    NARCIS (Netherlands)

    Morell, P.; Piqueras-Fiszman, B.; Hernando, I.; Fiszman, S.

    2015-01-01

    Protein is recognized as the macronutrient with the highest satiating ability. Yogurt can be an excellent basis for designing satiating food as it is protein-based food product. Five different set-type yogurts were formulated by adding extra skim milk powder (MP), whey protein concentrate (WPC),

  9. Incentive-based control of ad hoc networks: a performance study

    NARCIS (Netherlands)

    Göbel, F.; Kresinski, A.E.; Mandjes, M.R.H.

    2009-01-01

    Ad hoc networks are self-configuring networks of mobile nodes, connected by wireless links. If a destination node is beyond the transmission range of an origin node, then the nodes must cooperate to provide a multi-hop route. Any node can act as a sender, receiver or transit node. It is clear that i

  10. Refined Holographic Entanglement Entropy for the AdS Solitons and AdS black Holes

    CERN Document Server

    Ishihara, Masafumi; Ning, Bo

    2012-01-01

    We consider the refinement of the holographic entanglement entropy on a disk region for the holographic dual theories to the AdS solitons and AdS black holes, including the corrected ones by the Gauss-Bonnet term. The AdS soliton is dual to a gapped system with an IR fixed-point. The refinement is obtained by extracting the UV-independent piece of the holographic entanglement entropy. We then study the renormalization group (RG) flow of the refinement by tuning the linear size of the chosen disk region. Our main results are (i) the RG flow of the refinement decreases monotonically for most of the cases; (ii) there is no topological entanglement entropy for AdS$_5$ soliton even with Gauss-Bonnet correction; (iii) for the AdS black holes, the refinement obeys the volume law at IR regime, and the transition between UV and IR regimes is a smooth crossover; however, the crossover will turn into phase transition by the Gauss-Bonnet correction; (iv) for the AdS solitons, there are discontinuous phase transitions bet...

  11. Half BPS states in AdS5 x Yp,q

    International Nuclear Information System (INIS)

    We study a class of solutions of IIB supergravity which are asymptotically AdS5 x Yp,q. They have an R x SO(4) x SU(2) x U(1) isometry and preserve half of the 8 supercharges of the background geometry. They are described by a set of second order differential equations that we have found and analysed in a previous paper, where we studied 1/8 BPS states in the maximally supersymmetric AdS5 x S5 background. These geometries correspond to certain chiral primary operators of the N = 1 superconformal quiver theories, dual to IIB theory on AdS5 x Yp,q. We also show how to recover the AdS5 x Yp,q backgrounds by suitably doubling the number of preserved supersymmetries. We then solve the differential equations perturbatively in a large AdS5 radius expansion, imposing asymptotic AdS5 x Yp,q boundary conditions. We compute the global baryonic and mesonic charges, including the R-charge. As for the computation of the mass, i.e. the conformal dimension Δ of the dual field theory operators, which is notoriously subtle in asymptotically AdS backgrounds, we adopt the general formalism due to Wald and collaborators, which gives a finite result, and verify the relation Δ = 3R/2, demanded by the N = 1 superconformal algebra

  12. ADS National Programmes: France

    International Nuclear Information System (INIS)

    Studies related to nuclear reactors and radioactive waste started at the French National Centre for Scientific research, CNRS, as a result of the French law on radioactive waste that was published in 1991. They were initially organized around the programme PACE (Physique pour l’Aval du Cycle Electronucléaire = physics of the back end of the nuclear fuel cycle), which became PACEN (Physique pour l’Aval du Cycle et production d’Energie Nucléaire = Physics of the back end of the nuclear fuel cycle and production of nuclear energy) in 2006. Research on accelerator driven systems was from the beginning part of this programme. This research is mainly funded by the National Institute for Nuclear end Particle Physics (IN2P3) of CNRS and within the EURATOM European programmes (FP5, 6 and 7). The programme took place in several stages, and covered various scientific fields, benefitting from expertise of CNRS in the field. More specifically, it aimed and still aims to: – Test and verify the feasibility and design of the ADS concept, in terms of neutronics, physics of materials, design of the accelerator and tests of its prototypical components that have been built (or are at present under construction); – Measure and-or improve nuclear data related to radioactive waste transmutation. Today, most of the activities in support to ADS development carried out by CNRS focus on accelerator developments, GUINEVERE (Generator of Uninterrupted Intense NEutron at the lead VEnus REactor) experiment, ADS core studies, deployment scenarios and nuclear data measurements. The CEA R&D programmes on ADS are mainly focused on the European project EUROTRANS of the 6th Framework programme (2005–2010) and continued in the FREYA project of the 7th Framework Programme

  13. Ambitwistors, oscillators and massless fields on $AdS_5$

    CERN Document Server

    Uvarov, D V

    2016-01-01

    Positive energy unitary irreducible representations of $SU(2,2)$ can be constructed with the aid of bosonic oscillators in (anti)fundamental representation of $SU(2)_L\\times SU(2)_R$ that are closely related to Penrose twistors. Starting with the correspondence between the doubleton representations, homogeneous functions on projective twistor space and on-shell $SL(2,\\mathbb C)$ generalized Weyl curvature spinors and their low-spin counterparts, we study in the similar way the correspondence between the massless representations, homogeneous functions on ambitwistor space and, via the Penrose transform, with the gauge fields on Minkowski boundary of $AdS_5$. The possibilities of reconstructing massless fields on $AdS_5$ and some applications are also discussed.

  14. An Empirical Comparative Study of Checklist-based and Ad Hoc Code Reading Techniques in a Distributed Groupware Environment

    Directory of Open Access Journals (Sweden)

    Adenike O. Osofisan

    2009-09-01

    Full Text Available Software inspection is a necessary and important tool for software quality assurance. Since it was introduced by Fagan at IBM in 1976, arguments exist as to which method should be adopted to carry out the exercise, whether it should be paper-based or tool-based, and what reading technique should be used on the inspection document. Extensive works have been done to determine the effectiveness of reviewers in paper-based environment when using ad hoc and checklist reading techniques. In this work, we take the software inspection research further by examining whether there is going to be any significant difference in defect detection effectiveness of reviewers when they use either ad hoc or checklist reading techniques in a distributed groupware environment. Twenty final year undergraduate students of computer science, divided into ad hoc and checklist reviewers groups of ten members each were employed to inspect a medium-sized java code synchronously on groupware deployed on the Internet. The data obtained were subjected to tests of hypotheses using independent t-test and correlation coefficients. Results from the study indicate that there are no significant differences in the defect detection effectiveness, effort in terms of time taken in minutes and false positives reported by the reviewers using either ad hoc or checklist based reading techniques in the distributed groupware environment studied.Key words: Software Inspection, Ad hoc, Checklist, groupware.

  15. Numerical Study on Anti-Penetration Process of Alumina Ceramic (AD95) to Tungsten Long Rod Projectiles

    Science.gov (United States)

    Zhang, Xianfeng; Zhang, Niansong; Li, Yongchi

    Numerical studies were conducted on the ballistic performance of alumina ceramic (AD95) tiles based on depth of penetration method, when subjected to normal impact of tungsten long rod projectiles at velocities ranging from 1100 to 2000 ms-1. The residual depth on after-effect target was derived in each case, and the ballistic efficiency factor was determined using the corresponding penetration depth on medium carbon steel. Anti-penetration experiment study of the AD95 ceramic tiles to tungsten long rod projectiles has been carried out to verify the accuracy of numerical simulation model. The result shows that numerical simulation results agree well with the corresponding experiment results and AD95 ceramic has excellent ballistic performance than medium carbon steel. The ballistic efficiency factor increases with velocity increasing when impact velocity lower than 1300 ms-1, and when it was higher than 1300 ms-1 the ballistic efficiency factor has almost no difference.

  16. Wormholes in AdS

    OpenAIRE

    Maldacena, Juan; Maoz, Liat

    2004-01-01

    We construct a few Euclidean supergravity solutions with multiple boundaries. We consider examples where the corresponding boundary field theory is well defined on each boundary. We point out that these configurations are puzzling from the AdS/CFT point of view. A proper understanding of the AdS/CFT dictionary for these cases might yield some information about the physics of closed universes.

  17. Simulation Based: Study and Analysis of Routing Protocol in Vehicular Ad-hoc Network Environment

    OpenAIRE

    Vaishali D. Khairnar; Pradhan, Dr. S. N.

    2012-01-01

    A Vehicular Ad hoc Network (VANET) consists of vehicles which communicate with each other and exchange data via wireless communication links available between the vehicles which are in communication ranges of vehicles to improve the road safety in city. The communication between vehicles is used to provide road safety, comfort and entertainment. The performance of communication depends on how better routing takes place in the network. Routing data between the source and destination vehicle de...

  18. Adding Ajax

    CERN Document Server

    Powers, Shelley

    2007-01-01

    Ajax can bring many advantages to an existing web application without forcing you to redo the whole thing. This book explains how you can add Ajax to enhance, rather than replace, the way your application works. For instance, if you have a traditional web application based on submitting a form to update a table, you can enhance it by adding the capability to update the table with changes to the form fields, without actually having to submit the form. That's just one example.Adding Ajax is for those of you more interested in extending existing applications than in creating Rich Internet Applica

  19. EXPERIMENTAL STUDY OF NETWORK BASED NOVEL ADAPTIVE ROUTING ALGORITHM FOR WIRELESS AD-HOC NETWORK

    Directory of Open Access Journals (Sweden)

    Jagrut Solanki

    2015-10-01

    Full Text Available Ad hoc network is a collection of mobile nodes which dynamically form a temporary network without any infrastructure or centralize entity. There are number of routing protocol exists in ad hoc network and this protocols have been compared. These protocols are like DSR (Dynamic Source Routing, AODV (Ad-hoc On Demand Distance Vector Routing Algorithm, and TORA (Temporally Ordered Routing Algorithm like more. AODV is Reactive routing protocol. We modify the existing AODV protocol. All Routing Protocol have different Strategies of routing like End to End delay, Packet delivery ratio, Traffic overhead and Power Consumptions. Routing Deals with route discovery between source and destination. Aim of Dissertation is to improve route error tolerance mechanism of AODV. In our propose scheme the transmission starts from closest neighbor node if the link fail in middle of the transmission. That shows very important reductions in delay and it improves the packet delivery ratio. It also reduces the routing overhead by reducing frequency of route discovery process.

  20. A Comparative Study on the Uptake and Toxicity of Nickel Added in the Form of Different Salts to Maize Seedlings

    Directory of Open Access Journals (Sweden)

    Jing Nie

    2015-11-01

    Full Text Available In soil ecotoxicological studies, a toxic metal is usually added in the form of either an inorganic or organic salt with relatively high solubility. Nitrate, chloride, acetate, or sulfate are commonly considered as valid options for that aim. However, recent studies have shown that different salts of the same metal at the same cationic concentration may exhibit different toxicities to plants and soil organisms. This information should be considered when selecting data to use for developing toxicological criteria for soil environment. A comparative study was carried out to evaluate the toxicity of five nickel (Ni salts: NiCl2, NiSO4, Ni(II-citrate, Ni(CH3COO2, and Ni(II-EDTA (ethylenediaminetetraacetate, on maize seedlings. The plant metrics used were plant height, shoot and root biomass, leaf soluble sugars and starch, and the Ni contents of the shoots and roots. The results indicated that when Ni was added to the soil, toxicity varied with the selected anionic partner with the following toxicity ranking NiSO4 < Ni(CH3COO2 < Ni(II-citrate < NiCl2 < Ni(II-EDTA. Taking the plant-height metric as an example, the effective concentrations for 50% inhibition (EC50 were 3148 mg·kg−1 for NiSO4, 1315 mg·kg−1 for NiCl2, and 89 mg·kg−1 for Ni(II-EDTA. Compared with the Ni in the other salts, that in Ni(II-EDTA was taken up the most efficiently by the maize roots and, thus, resulted in the greatest toxic effects on the plants. Nickel generally reduced leaf soluble sugars, which indicated an effect on plant carbohydrate metabolism. The outcome of the study demonstrates that different salts of the same metal have quite different ecotoxicities. Therefore, the anionic counterpart of a potentially toxic metal cation must be taken into account in the development of ecotoxicological criteria for evaluating the soil environment, and a preferred approach of leaching soil to reduce the anionic partner should also be considered.

  1. A Comparative Study on the Uptake and Toxicity of Nickel Added in the Form of Different Salts to Maize Seedlings.

    Science.gov (United States)

    Nie, Jing; Pan, Yuqiang; Shi, Jing; Guo, Yan; Yan, Zengguang; Duan, Xiaoli; Xu, Meng

    2015-12-01

    In soil ecotoxicological studies, a toxic metal is usually added in the form of either an inorganic or organic salt with relatively high solubility. Nitrate, chloride, acetate, or sulfate are commonly considered as valid options for that aim. However, recent studies have shown that different salts of the same metal at the same cationic concentration may exhibit different toxicities to plants and soil organisms. This information should be considered when selecting data to use for developing toxicological criteria for soil environment. A comparative study was carried out to evaluate the toxicity of five nickel (Ni) salts: NiCl₂, NiSO₄, Ni(II)-citrate, Ni(CH₃COO)₂, and Ni(II)-EDTA (ethylenediaminetetraacetate), on maize seedlings. The plant metrics used were plant height, shoot and root biomass, leaf soluble sugars and starch, and the Ni contents of the shoots and roots. The results indicated that when Ni was added to the soil, toxicity varied with the selected anionic partner with the following toxicity ranking NiSO₄ < Ni(CH₃COO)₂ < Ni(II)-citrate < NiCl₂ < Ni(II)-EDTA. Taking the plant-height metric as an example, the effective concentrations for 50% inhibition (EC50) were 3148 mg·kg(-1) for NiSO₄, 1315 mg·kg(-1) for NiCl₂, and 89 mg·kg(-1) for Ni(II)-EDTA. Compared with the Ni in the other salts, that in Ni(II)-EDTA was taken up the most efficiently by the maize roots and, thus, resulted in the greatest toxic effects on the plants. Nickel generally reduced leaf soluble sugars, which indicated an effect on plant carbohydrate metabolism. The outcome of the study demonstrates that different salts of the same metal have quite different ecotoxicities. Therefore, the anionic counterpart of a potentially toxic metal cation must be taken into account in the development of ecotoxicological criteria for evaluating the soil environment, and a preferred approach of leaching soil to reduce the anionic partner should also be considered. PMID:26633435

  2. Design and rationale for RE-VERSE AD : A phase 3 study of idarucizumab, a specific reversal agent for dabigatran

    NARCIS (Netherlands)

    Pollack, Charles V.; Reilly, Paul A.; Bernstein, Richard; Dubiel, Robert; Eikelboom, John; Glund, Stephan; Huisman, Menno V.; Hylek, Elaine; Kam, Chak-Wah; Kamphuisen, Pieter W.; Kreuzer, Joerg; Levy, Jerrold H.; Sellke, Frank; Stangier, Joachim; Steiner, Thorsten; Wang, Bushi; Weitz, Jeffrey I.

    2015-01-01

    Idarucizumab, a Fab fragment directed against dabigatran, produced rapid and complete reversal of the anticoagulation effect of dabigatran in animals and in healthy volunteers. The Study of the REVERSal Effects of Idarucizumab in Patients on Active Dabigatran (RE-VERSE AD (TM)) is a global phase 3 p

  3. The impact of student composition on schools’ value-added performance : a comparison of seven empirical studies

    NARCIS (Netherlands)

    Timmermans, Anneke C.; Thomas, Sally M.

    2015-01-01

    In many countries, policy makers struggle with the development of value added indicators of school performance for educational accountability purposes and in particular with the choice whether school context measured in the form of student composition variables should be included. This study investi

  4. Baby Skyrmions in AdS

    CERN Document Server

    Elliot-Ripley, Matthew

    2015-01-01

    We study the baby Skyrme model in a pure AdS background without a mass term. The tail decays and scalings of massless radial solutions are demonstrated to take a similar form to those of the massive flat space model, with the AdS curvature playing a similar role to the flat space pion mass. We also numerically find minimal energy solutions for a range of higher topological charges and find that they form concentric ring-like solutions. Popcorn transitions (named in analogy with studies of toy models of holographic QCD) from an n layer to an n+1-layer configuration are observed at topological charges 9 and 27 and further popcorn transitions for higher charges are predicted. Finally, a point-particle approximation for the model is derived and used to successfully predict the ring structures and popcorn transitions for higher charge solitons.

  5. Stabilization of Microtubule-Unbound Tau via Tau Phosphorylation at Ser262/356 by Par-1/MARK Contributes to Augmentation of AD-Related Phosphorylation and Aβ42-Induced Tau Toxicity.

    Directory of Open Access Journals (Sweden)

    Kanae Ando

    2016-03-01

    Full Text Available Abnormal accumulation of the microtubule-interacting protein tau is associated with neurodegenerative diseases including Alzheimer's disease (AD. β-amyloid (Aβ lies upstream of abnormal tau behavior, including detachment from microtubules, phosphorylation at several disease-specific sites, and self-aggregation into toxic tau species in AD brains. To prevent the cascade of events leading to neurodegeneration in AD, it is essential to elucidate the mechanisms underlying the initial events of tau mismetabolism. Currently, however, these mechanisms remain unclear. In this study, using transgenic Drosophila co-expressing human tau and Aβ, we found that tau phosphorylation at AD-related Ser262/356 stabilized microtubule-unbound tau in the early phase of tau mismetabolism, leading to neurodegeneration. Aβ increased the level of tau detached from microtubules, independent of the phosphorylation status at GSK3-targeted SP/TP sites. Such mislocalized tau proteins, especially the less phosphorylated species, were stabilized by phosphorylation at Ser262/356 via PAR-1/MARK. Levels of Ser262 phosphorylation were increased by Aβ42, and blocking this stabilization of tau suppressed Aβ42-mediated augmentation of tau toxicity and an increase in the levels of tau phosphorylation at the SP/TP site Thr231, suggesting that this process may be involved in AD pathogenesis. In contrast to PAR-1/MARK, blocking tau phosphorylation at SP/TP sites by knockdown of Sgg/GSK3 did not reduce tau levels, suppress tau mislocalization to the cytosol, or diminish Aβ-mediated augmentation of tau toxicity. These results suggest that stabilization of microtubule-unbound tau by phosphorylation at Ser262/356 via the PAR-1/MARK may act in the initial steps of tau mismetabolism in AD pathogenesis, and that such tau species may represent a potential therapeutic target for AD.

  6. Study of Un-added Allowance of Draping-Planar Designing Garment Prototype for Young Ladies

    Institute of Scientific and Technical Information of China (English)

    李兴刚; 李元虹; 苏同岳

    2003-01-01

    As for the theory and method in garment structural design according to human figures,a principle for garment design,i.e.body-fitting without added allowance,and a combination of draping and planar design (DPD hereunder) for young ladies has been put forward,and,also,a DPD garment prototype for them has been established.And the applied formulae for extensively-practicing operation have been set up,which proves to be,with actual samples,a systematic and practical garment structural designing theory and approach.

  7. Effects of dietary vanadium on growth and lipid storage in a larval anuran: results from studies employing ad libitum and rationed feeding.

    Science.gov (United States)

    Rowe, Christopher L; Heyes, Andrew; Hopkins, William

    2009-01-31

    Vanadium (V) exerts a variety of effects related to metabolic function in vertebrates, including modifying glycolytic pathways and lipid metabolism. However, little is known about toxicity of V to wildlife in natural systems. We conducted parallel, independent studies to evaluate the effect of dietary exposure to vanadium on survival, metabolism, growth, and lipid storage of larval leopard frogs (Rana sphenocephala). In one study ("Ad lib") larvae were fed unlimited food and in the other ("Ration") larvae were fed a restricted diet. Experimental diets contained 10 ppm dw V(total) (Control, "C"), 109 ppm (Low, "L"), and 363 ppm (High, "H"). In neither study did V affect metabolic rate or survival to forelimb emergence. However, in the Ration study, 31% of individuals in H that had initiated metamorphosis died prior to completion of metamorphosis, compared with 22% in M and 9% in C, however the difference was not significant at alpha=0.05. Mortality during metamorphosis in the Ad lib study was more variable, yet followed a similar trend (26, 14, and 12% mortality in H, L, and C). In both studies, individuals that died during the metamorphic period were smaller at the time of forelimb emergence than those that survived. In the Ration study, individuals in H also had significantly lower growth rates, delayed metamorphosis, and reduced lipid content at metamorphosis compared to C and L. Growth was not affected by V in the Ad lib study. Our results suggest that habitat contamination by V may present risks to amphibians during the metamorphic period attributable to energetic responses influencing size at the initiation of metamorphosis and body lipid stores. Furthermore, while we cannot make formal comparisons between the studies, our results imply that protocols that employ ad libitum feeding regimes could fail to capture the effects of contaminants as they may be expressed in natural situations in which resources are typically more limited.

  8. D-branes in Lorentzian AdS(3)

    CERN Document Server

    Israel, D

    2005-01-01

    We study the exact construction of D-branes in Lorentzian AdS(3). We start by defining a family of conformal field theories that gives a natural Euclidean version of the SL(2,R) CFT and does not correspond to H(3)+, the analytic continuation of AdS(3). We argue that one can recuperate the exact CFT results of Lorentzian AdS(3), upon an analytic continuation in the moduli space of these conformal field theories. Then we construct exact boundary states for various symmetric and symmetry-breaking D-branes in AdS(3).

  9. A study of the properties and functions of CMC-bonial BBV/ADS; Estudo das propriedades e funcoes do CMC-bonial BBV/ADS

    Energy Technology Data Exchange (ETDEWEB)

    Oliveira, Telma de; S. Filho, Antonio Alves [Grupo Ultra, XX (Brazil)

    1989-12-31

    The use of CMC (Carboxy methyl cellulose) in drilling fluids is consolidated in the national and international markets. Properties such as water retention, rheology control and viscosifying capacity have made this polymer a largely used additive for drilling fluids. The goal of this paper is to stress the effects of the use of low viscosity CMC (Bonial BBV/ADS). We stress also filtrate reduction and control of the rheological properties of the fluid, through flow limits. We demonstrate the effects of substitution degree and molecular weight, through viscosity, on the properties required for application. (author) 6 refs., 9 figs., 4 tabs.

  10. Feasibility study of a wearable exoskeleton for children: is the gait altered by adding masses on lower limbs?

    Directory of Open Access Journals (Sweden)

    Stefano Rossi

    Full Text Available We are designing a pediatric exoskeletal ankle robot (pediatric Anklebot to promote gait habilitation in children with Cerebral Palsy (CP. Few studies have evaluated how much or whether the unilateral loading of a wearable exoskeleton may have the unwanted effect of altering significantly the gait. The purpose of this study was to evaluate whether adding masses up to 2.5 kg, the estimated overall added mass of the mentioned device, at the knee level alters the gait kinematics. Ten healthy children and eight children with CP, with light or mild gait impairment, walked wearing a knee brace with several masses. Gait parameters and lower-limb joint kinematics were analyzed with an optoelectronic system under six conditions: without brace (natural gait and with masses placed at the knee level (0.5, 1.0, 1.5, 2.0, 2.5 kg. T-tests and repeated measures ANOVA tests were conducted in order to find noteworthy differences among the trial conditions and between loaded and unloaded legs. No statistically significant differences in gait parameters for both healthy children and children with CP were observed in the five "with added mass" conditions. We found significant differences among "natural gait" and "with added masses" conditions in knee flexion and hip extension angles for healthy children and in knee flexion angle for children with CP. This result can be interpreted as an effect of the mechanical constraint induced by the knee brace rather than the effect associated with load increase. The study demonstrates that the mechanical constraint induced by the brace has a measurable effect on the gait of healthy children and children with CP and that the added mass up to 2.5 kg does not alter the lower limb kinematics. This suggests that wearable devices weighing 25 N or less will not noticeably modify the gait patterns of the population examined here.

  11. Metabolomic study of plasma from female mink (Neovison vison) with low and high residual feed intake during restrictive and ad libitum feeding.

    Science.gov (United States)

    Hedemann, Mette Skou; Damgaard, Birthe Marie

    2012-12-01

    Metabolite profiling may elucidate changes in metabolic pathways under various physiological or nutritional conditions. In the present study two groups of female mink characterised as having a high (16 mink) or low (14 mink) residual feed intake were investigated during restrictive and ad libitum feeding. Blood samples were collected three times during the experimental period; during restrictive feeding, and four days and three weeks after the change to ad libitum feeding. Plasma samples were subjected to liquid chromatography mass spectrometry non-targeted metabolomics. Subjecting data to principal component analysis showed that there was no grouping of the data according to the residual feed intake. In contrast, data were clearly grouped according to feeding level. Identification of the metabolites responsible for this grouping showed that the plasma level of metabolites related to mobilisation of energy was high during restrictive feeding, e.g. betaine, carnitine, and creatine. During ad libitum feeding the plasma level of metabolites that can be characterised as biomarkers of meat intake (creatinine, carnosine, 1- and 3 methylhistidine) was high. The plasma level of lysophosphatidylcholine species was highest after four days of ad libitum feeding suggesting a short term imbalance in the transport or metabolism of these metabolites when changing the feeding level. PMID:23123310

  12. Role of Adding Spironolactone and Renal Denervation in True Resistant Hypertension: One-Year Outcomes of Randomized PRAGUE-15 Study.

    Science.gov (United States)

    Rosa, Ján; Widimský, Petr; Waldauf, Petr; Lambert, Lukáš; Zelinka, Tomáš; Táborský, Miloš; Branny, Marian; Toušek, Petr; Petrák, Ondřej; Čurila, Karol; Bednář, František; Holaj, Robert; Štrauch, Branislav; Václavík, Jan; Nykl, Igor; Krátká, Zuzana; Kociánová, Eva; Jiravský, Otakar; Rappová, Gabriela; Indra, Tomáš; Widimský, Jiří

    2016-02-01

    This randomized, multicenter study compared the relative efficacy of renal denervation (RDN) versus pharmacotherapy alone in patients with true resistant hypertension and assessed the effect of spironolactone addition. We present here the 12-month data. A total of 106 patients with true resistant hypertension were enrolled in this study: 52 patients were randomized to RDN and 54 patients to the spironolactone addition, with baseline systolic blood pressure of 159±17 and 155±17 mm Hg and average number of drugs 5.1 and 5.4, respectively. Twelve-month results are available in 101 patients. The intention-to-treat analysis found a comparable mean 24-hour systolic blood pressure decline of 6.4 mm Hg, P=0.001 in RDN versus 8.2 mm Hg, P=0.002 in the pharmacotherapy group. Per-protocol analysis revealed a significant difference of 24-hour systolic blood pressure decline between complete RDN (6.3 mm Hg, P=0.004) and the subgroup where spironolactone was added, and this continued within the 12 months (15 mm Hg, P= 0.003). Renal artery computed tomography angiograms before and after 1 year post-RDN did not reveal any relevant changes. This study shows that over a period of 12 months, RDN is safe, with no serious side effects and no major changes in the renal arteries. RDN in the settings of true resistant hypertension with confirmed compliance is not superior to intensified pharmacological treatment. Spironolactone addition (if tolerated) seems to be more effective in blood pressure reduction.

  13. Experimental Study on Shear Fatigue Behavior and Stiffness Performance of Warm Mix Asphalt by adding Synthetic Wax

    CERN Document Server

    Petit, Christophe; Canestrari, Francesco; Pannunzio, Valter; Virgili, Amadeo

    2012-01-01

    Synthetic waxes produced by standard and registered processes may be used to manufacture Warm Mix Asphalt (WMA), which is a modified asphalt concrete produced, applied and compacted at temperatures below those typically required. This feature leads to environmental benefits, such as reduced energy consumption, gas and fume emissions, as well as to economic/operational advantages, such as lower production costs and greater hauling distances for extended construction seasons with tighter schedules. The present article serves to compare the mechanical performance of a WMA produced by adding synthetic wax with a traditional Hot Mix Asphalt (HMA) specimen, in terms of shear fatigue response and both complex and stiffness moduli. The experimental results and related modeling work demonstrate that adding synthetic wax into the WMA composition does not hinder either the destructive or non-destructive performance of an HMA, and this finding is corroborated by respectively measuring fatigue life and stiffness.

  14. Study on transient beam loading compensation for China ADS proton linac injector II

    CERN Document Server

    Gao, Zheng; Wang, Xian-Wu; Chang, Wei; Zhang, Rui-Feng; Zhu, Zheng-Long; Zhang, Sheng-Hu; Chen, Qi; Powers, Tom

    2016-01-01

    Significant transient beam loading effects were observed during beam commissioning tests of prototype II of the injector for the Accelerator Driven Sub-critical (ADS) system, which took place at the Institute of Modern Physics, Chinese Academy of Sciences, between October and December 2014. During these tests experiments were performed with CW operation of the cavities with pulsed beam current, and the system was configured to make use of a prototype digital low level radio frequency (LLRF) controller. The system was originally operated in pulsed mode with a simple PID feedback control algorithm, which was not able to maintain the desired gradient regulation during pulsed 10 mA beam operations. A unique simple transient beam loading compensation method which made use of a combination of PI feedback and feedforward control algorithm was implemented in order to significantly reduce the beam induced transient effect in the cavity gradients. The superconducting cavity field variation was reduced to less than 1.7%...

  15. Study on Sound Absorption Properties of Coconut Coir Fibre Reinforced Composite with Added Recycled Rubber

    Directory of Open Access Journals (Sweden)

    S. Mahzan

    2010-06-01

    Full Text Available Sound pollutions have become worsen and creating concerns for many peoples. Conventionally, expensive sound absorption materials are employed to control noise disturbances. However, recent developments on natural fibres have created interest for researchers especially for acoustics application purposes. This paper investigates the viability of coconut coir added with recycled rubber to be implemented as sound absorption panel. The composite is constructed at prescribed percentages of fillers and polyurethane as resin. The two-microphone method was applied to obtain the acoustic properties of the samples. The samples were also tested for physical properties such as density and porosity, as well as the microstructures. The results demonstrate good acoustics performances and highlight the potential of the coconut coir reinforced with recycled rubber as the sound absorption panel.

  16. Impact of Throughput in Enhancing the Efficiency of Cognitive Radio Ad Hoc Network - A Study

    Directory of Open Access Journals (Sweden)

    V. Jayaraj

    2013-09-01

    Full Text Available Cognitive Radio Ad Hoc Networks (CRAHNs constitute a viable solution to solve the current problems of inefficiency in the spectrum allocation, and to deploy highly reconfigurable and self-organizing wireless networks. Cognitive Radio (CR devices are envisaged to utilize the spectrum in an opportunistic way by dynamically accessing different licensed portions of the spectrum. However the phenomena of channel fading and primary cum secondary interference in cognitive radio networks does not guarantee application demands to be achieved continuously over time. Availability of limited spectrum and the inadequate spectrum resource usage necessitates a new communication standard to utilize the existing wireless spectrum opportunistically. This paper discusses currently existing mechanism for providing better efficiency by utilizing cognitive network intelligence. The frequencies used are utilized to the maximum extent without any interference. This paper aims in comparing the techniques used for enhancing the throughput in CR.

  17. Small black holes in global AdS spacetime

    Science.gov (United States)

    Jokela, Niko; Pönni, Arttu; Vuorinen, Aleksi

    2016-04-01

    We study the properties of two-point functions and quasinormal modes in a strongly coupled field theory holographically dual to a small black hole in global anti-de Sitter spacetime. Our results are seen to smoothly interpolate between known limits corresponding to large black holes and thermal AdS space, demonstrating that the Son-Starinets prescription works even when there is no black hole in the spacetime. Omitting issues related to the internal space, the results can be given a field theory interpretation in terms of the microcanonical ensemble, which provides access to energy densities forbidden in the canonical description.

  18. Note about a pure spin-connection formulation of general relativity and spin-2 duality in (A)dS

    Science.gov (United States)

    Basile, Thomas; Bekaert, Xavier; Boulanger, Nicolas

    2016-06-01

    We investigate the problem of finding a pure spin-connection formulation of general relativity with nonvanishing cosmological constant. We first revisit the problem at the linearized level and find that the pure spin-connection, quadratic Lagrangian, takes a form reminiscent to Weyl gravity, given by the square of a Weyl-like tensor. Upon Hodge dualization, we show that the dual gauge field in (A )dSD transforms under G L (D ) in the same representation as a massive graviton in the flat spacetime of the same dimension. We give a detailed proof that the physical degrees of freedom indeed correspond to a massless graviton propagating around the (anti-) de Sitter background and finally speculate about a possible nonlinear pure-connection theory dual to general relativity with cosmological constant.

  19. Sources of ground movement at Vesuvius before the AD 79 eruption: Evidence from contemporary accounts and archaeological studies

    OpenAIRE

    Marturano, A.; Istituto Nazionale di Geofisica e Vulcanologia, Sezione OV, Napoli, Italia

    2008-01-01

    Historical sources have recorded earthquake shocks, their effects and difficulties that local inhabitants experienced before the AD 79 Pompeii eruption. Archaeological studies pointed out the effects of such seismicity, and have also evidenced that several water crises were occurring at Pompeii in that period. Indeed numerous sources show that, at the time of eruption, and probably some time before, the civic aqueduct, having ceased to be supplied by the regional one, was out of o...

  20. Study on transient beam loading compensation for China ADS proton linac injector II

    Science.gov (United States)

    Gao, Zheng; He, Yuan; Wang, Xian-Wu; Chang, Wei; Zhang, Rui-Feng; Zhu, Zheng-Long; Zhang, Sheng-Hu; Chen, Qi; Powers, Tom

    2016-05-01

    Significant transient beam loading effects were observed during beam commissioning tests of prototype II of the injector for the accelerator driven sub-critical (ADS) system, which took place at the Institute of Modern Physics, Chinese Academy of Sciences, between October and December 2014. During these tests experiments were performed with continuous wave (CW) operation of the cavities with pulsed beam current, and the system was configured to make use of a prototype digital low level radio frequency (LLRF) controller. The system was originally operated in pulsed mode with a simple proportional plus integral and deviation (PID) feedback control algorithm, which was not able to maintain the desired gradient regulation during pulsed 10 mA beam operations. A unique simple transient beam loading compensation method which made use of a combination of proportional and integral (PI) feedback and feedforward control algorithm was implemented in order to significantly reduce the beam induced transient effect in the cavity gradients. The superconducting cavity field variation was reduced to less than 1.7% after turning on this control algorithm. The design and experimental results of this system are presented in this paper. Supported by National Natural Science Foundation of China (91426303, 11525523)

  1. A Study on Contributory Group Key Agreements for Mobile Ad Hoc Networks

    Directory of Open Access Journals (Sweden)

    CH. V. Raghavendran

    2013-04-01

    Full Text Available Wireless networks, in particular Mobile Ad hoc Networks (MANETs have revolutionized the field of networking with increasing number of their commercial and military applications. Security on the other hand, is now an essential requirement for these applications. However, the limitations of the dynamic, infrastructure-less nature of MANETs impose major difficulties in establishing a secure framework suitable for such services. Security for MANETs is a dynamic area of research. Most of the traditional routing protocols proposed for MANETs are focused on routing only not on the security aspects. As in traditional wired networks, wireless networks also require security. Unlike the wired networks, where dedicated routers, servers control the network, in MANETs nodes act both as terminals and also as routers for other nodes. A popular mechanism to satisfy the security requirements is the Group Key Management in which the group key is to be shared by each group communication participant. But to establish and manage the group key efficiently imposes new challenges – especially in infrastructure less MANETs. The basic needs of such networks require that the group key schemes must demonstrate not only high performance but also fault-tolerance.

  2. Study of the thermo-magnetic fluctuations in carbon nano-tubes added Bi-2223 superconductors

    Science.gov (United States)

    Saoudel, A.; Amira, A.; Boudjadja, Y.; Mahamdioua, N.; Amirouche, L.; Varilci, A.; Altintas, S. P.; Terzioglu, C.

    2013-11-01

    We have investigated the effect of addition of carbon nano-tubes (CNT) on the properties of Bi1.6Pb0.4Sr2Ca2Cu3Oy superconductors. The samples are prepared from commercial powders with addition of 0.1 wt% of CNT. They are characterized by XRD, SEM and magneto-resistivity in the transition region. As it was reported for CNT added Y-123 compounds, the refined cell parameters are practically independent of this kind of addition. Under applied magnetic field, a large broadening of resistive transition is observed. The dissipative behavior of resistivity can be explained using the well known expression, ρ=ρ0(T/Tg-1)S. The modified vortex-glass to liquid transition theory is used to calculate the values of the glass-transition temperature Tg and the temperature and magnetic field dependent activation energy U0(B,T). These parameters are seen to decrease with CNT addition and applied magnetic field. Also, we have found that the undoped sample proves a better transition width, residual resistivity (ρ0) and a higher onset critical transition temperature of about 117.75 K. Also, the appearance of a double resistive transition for both samples is a confirmation of the existence of a secondary phase which plays the role of the weak links at the grain boundaries.

  3. Study on Doppler coefficient for metallic fuel fast reactor added hydrogeneous moderator

    Energy Technology Data Exchange (ETDEWEB)

    Hirakawa, Naohiro; Iwasaki, Tomohiko; Tsujimoto, Kazuhumi [Tohoku Univ., Sendai (Japan). Faculty of Engineering; Osugi, Toshitaka; Okajima, Shigeaki; Andoh, Masaki; Nemoto, Tatsuo; Mukaiyama, Takehiko

    1998-01-01

    A series of mock-up experiments for moderator added metallic fast reactor core was carried out at FCA to obtain the experimental verification for improvement of reactivity coefficients. Softened neutron spectrum increases Doppler effect by a factor of 2, and flatter adjoint neutron spectrum decreases Na void effect by a factor of 0.6 when hydrogen to heavy metal atomic number ratio is increased from 0.02 to 0.13. The experimental results are analyzed with SLALOM and CITATION-FBR, which is the standard design code system for a fast reactor at JAERI, and SRAC95 and CITATION-FBR. The present code system gives generally good agreement with the experimental results, especially by the use of the latter, the dependence of the Doppler effect to the hydrogen to fuel element atomic number density ratio is disappeared. Therefore, it looks possible to use the present code system for the conceptual design of a fast reactor system with hydrogeneous materials. (author)

  4. Gut-related radionuclide studies

    International Nuclear Information System (INIS)

    This project is concerned with the behavior of radioactive materials that may be ingested as a consequence of a reactor accident, unavoidable occupational exposure, or after release to the environment and incorporation into the food chain. Current emphasis is directed toward evaluating hazards from ingested actinides as a function of animal age, species, nutrition, and diet, or chemicophysical state of the actinide. Recent observations indicate that the influence of chemical form on plutonium absorption observed at high mass levels does not occur at low mass concentrations. For example, at doses of 0.6 μg/kg there was no difference between absorption of the carbonate, citrate or nitrate forms of plutonium. However, at 1.5 mg/kg, the citrate was absorbed in quantities 30 times higher than the nitrate. The opposite effect occurred for neptunium GI absorption. Furthermore, it was demonstrated that materials such as citrus fruit juices and calcium, as well as drugs that affect GI function (such as aspirin and DTPA), markedly influence GI absorption of plutonium. Such studies provide evidence that diet and nutritional state should be considered in establishing safe limits for radionuclides that may be ingested

  5. Performance Comparison Study of Connected Dominating Set Algorithms for Mobile Ad hoc Networks under Different Mobility Models

    Directory of Open Access Journals (Sweden)

    Natarajan Meghanathan

    2013-05-01

    Full Text Available The high-level contribution of this paper is an exhaustive simulation-based comparison study of three categories (density, node id and stability-based of algorithms to determine connected dominating sets (CDS for mobile ad hoc networks and evaluate their performance under two categories (random node mobility and grid-based vehicular ad hoc network of mobility models. The CDS algorithms studied are the maximum density-based (MaxD-CDS, node ID-based (ID-CDS and the minimum velocity-based (MinV-CDS algorithms representing the density, node id and stability categories respectively. The node mobility models used are the Random Waypoint model (representing random node mobility and the City Section and Manhattan mobility models (representing the grid-based vehicular ad hoc networks. The three CDS algorithms under the three mobility models are evaluated with respect to two critical performance metrics: the effective CDS lifetime (calculated taking into consideration the CDS connectivity and absolute CDS lifetime and the CDS node size. Simulations are conducted under a diverse set of conditions representing low, moderate and high network density, coupled with low, moderate and high node mobility scenarios. For each CDS, the paper identifies the mobility model that can be employed to simultaneously maximize the lifetime and minimize the node size with minimal tradeoff. For the two VANET mobility models, the impact of the grid block length on the CDS lifetime and node size is also evaluated.

  6. Catalytic domain of plasmid pAD1 relaxase TraX defines a group of relaxases related to restriction endonucleases.

    Science.gov (United States)

    Francia, María Victoria; Clewell, Don B; de la Cruz, Fernando; Moncalián, Gabriel

    2013-08-13

    Plasmid pAD1 is a 60-kb conjugative element commonly found in clinical isolates of Enterococcus faecalis. The relaxase TraX and the primary origin of transfer oriT2 are located close to each other and have been shown to be essential for conjugation. The oriT2 site contains a large inverted repeat (where the nic site is located) adjacent to a series of short direct repeats. TraX does not show any of the typical relaxase sequence motifs but is the prototype of a unique family of relaxases (MOBC). The present study focuses on the genetic, biochemical, and structural analysis of TraX, whose 3D structure could be predicted by protein threading. The structure consists of two domains: (i) an N-terminal domain sharing the topology of the DNA binding domain of the MarR family of transcriptional regulators and (ii) a C-terminal catalytic domain related to the PD-(D/E)XK family of restriction endonucleases. Alignment of MOBC relaxase amino acid sequences pointed to several conserved polar amino acid residues (E28, D152, E170, E172, K176, R180, Y181, and Y203) that were mutated to alanine. Functional analysis of these mutants (in vivo DNA transfer and cleavage assays) revealed the importance of these residues for relaxase activity and suggests Y181 as a potential catalytic residue similarly to His-hydrophobe-His relaxases. We also show that TraX binds specifically to dsDNA containing the oriT2 direct repeat sequences, confirming their role in transfer specificity. The results provide insights into the catalytic mechanism of MOBC relaxases, which differs radically from that of His-hydrophobe-His relaxases.

  7. The value of adding optics to ecosystem models: a case study

    Directory of Open Access Journals (Sweden)

    M. Fujii

    2007-10-01

    Full Text Available Many ecosystem models have been developed to study the ocean's biogeochemical properties, but most of these models use simple formulations to describe light penetration and spectral quality. Here, an optical model is coupled with a previously published ecosystem model that explicitly represents two phytoplankton (picoplankton and diatoms and two zooplankton functional groups, as well as multiple nutrients and detritus. Surface ocean color fields and subsurface light fields are calculated by coupling the ecosystem model with an optical model that relates biogeochemical standing stocks with inherent optical properties (absorption, scattering; this provides input to a commercially available radiative transfer model (Ecolight. We apply this bio-optical model to the equatorial Pacific upwelling region, and find the model to be capable of reproducing many measured optical properties and key biogeochemical processes in this region. Our model results suggest that non-algal particles largely contribute to the total scattering or attenuation (>50% at 660 nm but have a much smaller contribution to particulate absorption (<20% at 440 nm, while picoplankton dominate the total phytoplankton absorption (>95% at 440 nm. These results are consistent with the field observations. In order to achieve such good agreement between data and model results, however, key model parameters, for which no field data are available, have to be constrained. Sensitivity analysis of the model results to optical parameters reveals a significant role played by colored dissolved organic matter through its influence on the quantity and quality of the ambient light. Coupling explicit optics to an ecosystem model provides advantages in generating: (1 a more accurate subsurface light-field, which is important for light sensitive biogeochemical processes such as photosynthesis and photo-oxidation, (2 additional constraints on model parameters that help to reduce uncertainties in

  8. Radius-dependent gauge unification in AdS5

    OpenAIRE

    Choi, Kiwoon; Kim, Hyung Do; Kim, Ian-Woo

    2002-01-01

    We examine the relation of the 4-dimensional low energy coupling of bulk gauge boson in a slice of AdS5 to the 5-dimensional fundamental couplings as a function of the orbifold radius R. This allows us to address the gauge coupling unification in AdS5 by means of the radius running as well as the conventional momentum running. We then compute the radius dependence of 1-loop low energy couplings in generic AdS5 theory with 4-dimensional supersymmetry, and discuss the low energy predictions whe...

  9. Entanglement Temperature and Perturbed AdS$_3$ Geometry

    CERN Document Server

    Levine, Gregory

    2015-01-01

    In analogy to the first law of thermodynamics, the increase in entanglement entropy $\\delta S$ of a conformal field theory (CFT) is proportional to the increase in energy, $\\delta E$, of the subsystem divided by an effective entanglement temperature, $T_E$. Extending this analogy, we study entanglement entropy when the subsystem is perturbed by applying an external field, expressed as a coupling to a local marginal operator in the CFT. We show that the resulting entropy change is associated with a change in the entanglement temperature itself, leading to an equation analogous to the Clausius relation. Using AdS/CFT duality we develop a relationship between a perturbation in the local entanglement temperature, $\\delta T_E(x)$ of the CFT and the perturbation of the bulk AdS metric. Using the AdS$_3$ minimal surface as a probe, we can construct bulk metric perturbations from an exact numerical computation of the entanglement temperature in a two dimensional $c=1$ boundary theory deformed by a marginal perturbati...

  10. Educating Cataloger in The Electronic Environment : A Study For Education ad Training Programs in Egypt

    Directory of Open Access Journals (Sweden)

    Mohamed Fathy A.Hady

    2005-09-01

    Full Text Available A Study about education programs about cataloging in the electronic environment, the study deals the modern trends in cataloging courses of 7 departments for librarianship in Egypt.

  11. Ondansetron and simvastatin added to treatment as usual in patients with schizophrenia: study protocol for a randomized controlled trial

    Science.gov (United States)

    2013-01-01

    Background Negative symptoms and cognitive deficits are two partially-related features of schizophrenia which have a major negative impact on social function and objective quality of life. Standard drug treatments have little impact on either. There is some evidence that anti-inflammatory treatment may have beneficial effects in schizophrenia and major depression. Statins are cholesterol-lowering agents that have been found to be anti-inflammatory agents and are also known to decrease C-reactive protein (CRP). Ondansetron is a serotonin (5-HT3) receptor antagonist widely used to prevent nausea and vomiting in patients receiving chemotherapy for cancer. Small studies have suggested that ondansetron is effective as an adjunct drug in improving the symptoms of schizophrenia. Methods/design This is a two center, six-month, double-blind placebo controlled, factorial design study of ondansetron and/or simvastatin added to treatment as usual for patients suffering from schizophrenia, schizoaffective disorder, psychosis not otherwise specified or schizophreniform disorder. This will be a 2 × 2 design, with 54 patients in each cell, giving a total of 216 patients over three years. There will be a screening, a randomization and seven follow-up visits. Full clinical and neurocognitive assessments will be carried out at baseline (randomization), 14 weeks and at 26 weeks, while the positive and negative syndrome scale (PANSS), pill count and side effects checklist will be carried out at every visit. Simvastatin will be started at 20 mg once daily (OD), this will be increased to 40 mg after four weeks. Ondansetron will be administered in an 8 mg dose. Discussion Anti-inflammatory treatments have been shown to have some beneficial effects in schizophrenia. Both simvastatin and ondansetron provide some evidence of a reduction in symptoms compared to treatment as usual. The aim of this study is to establish the degree of improvement in negative symptoms with the addition of

  12. Photon gas thermodynamics in dS and AdS momentum spaces

    CERN Document Server

    Gorji, M A; Nozari, K; Vakili, B

    2016-01-01

    In this paper, we study thermostatistical properties of a photon gas in the framework of two deformed special relativity models defined by the cosmological coordinatizations of the de Sitter (dS) and anti-de Sitter (AdS) momentum spaces. The dS model is a doubly special relativity theory in which an ultraviolet length scale is invariant under the deformed Lorentz transformations. For the case of AdS model, however, the Lorentz symmetry breaks at the high energy regime. We show that the existence of a maximal momentum in dS momentum space leads to maximal pressure and temperature at the thermodynamical level while maximal internal energy and entropy arise for the case of the AdS momentum space due to the existence of a maximal kinematical energy. These results show the thermodynamical duality of these models much similar to their well-known kinematical duality.

  13. Photon gas thermodynamics in dS and AdS momentum spaces

    Science.gov (United States)

    Gorji, M. A.; Hosseinzadeh, V.; Nozari, K.; Vakili, B.

    2016-07-01

    In this paper, we study thermostatistical properties of a photon gas in the framework of two deformed special relativity models defined by the cosmological coordinatizations of the de Sitter (dS) and anti-de Sitter (AdS) momentum spaces. The dS model is a doubly special relativity theory in which an ultraviolet length scale is invariant under the deformed Lorentz transformations. For the case of the AdS model, however, the Lorentz symmetry breaks at the high energy regime. We show that the existence of a maximal momentum in dS momentum space leads to maximal pressure and temperature at the thermodynamical level, while maximal internal energy and entropy arise for the case of the AdS momentum space due to the existence of a maximal kinematical energy. These results show that the thermodynamical duality of these models is very similar to their well-known kinematical duality.

  14. ADS National Programmes: India

    International Nuclear Information System (INIS)

    Initial preliminary studies in India on ADS concepts were aimed toward applications such as, one way coupled booster reactor concept, thorium burner concept, enhancement of breeding rate of thorium– fueled fast reactors, and to incinerate Pu and minor actinides discharged from heavy water and fast reactors. These studies led to a roadmap on development of ADS subsystems in India, which was chalked out initially in June 2001. It was realized in these studies that the most challenging subsystem in terms of technology development and capital investment for ADS in India would be the high intensity proton accelerator, and that it must be accomplished in phased manner. Of the two alternative accelerator types, viz. the cyclotron and linear accelerator (linac), it is concluded that only linac would provide the necessary intense beam current for ADS applications. The energy amplifier (EA) scheme, with lead (45.5%) bismuth (55.5%) eutectic (LBE) as target & coolant, which was proposed in the early nineties would be one of the desired configurations of ADS for Indian applications. Additionally, subcritical reactor core of Indian Advanced Heavy Water Reactor (AHWR), with advantages of its low fission power density, and neutron economy is also a candidate among various ADS reactor configurations. These options of ADS configurations for thorium utilization are based on the neutronic properties of 233U isotope as fissile fuel, which are more or less similar in thermal and in moderately fast neutron spectra

  15. An ultra-wide bandwidth-based range/GPS tight integration approach for relative positioning in vehicular ad hoc networks

    Science.gov (United States)

    Shen, Feng; Wayn Cheong, Joon; Dempster, Andrew G.

    2015-04-01

    Relative position awareness is a vital premise for the implementation of emerging intelligent transportation systems, such as collision warning. However, commercial global navigation satellite systems (GNSS) receivers do not satisfy the requirements of these applications. Fortunately, cooperative positioning (CP) techniques, through sharing the GNSS measurements between vehicles, can improve the performance of relative positioning in a vehicular ad hoc network (VANET). In this paper, while assuming there are no obstacles between vehicles, a new enhanced tightly coupled CP technique is presented by adding ultra-wide bandwidth (UWB)-based inter-vehicular range measurements. In the proposed CP method, each vehicle fuses the GPS measurements and the inter-vehicular range measurements. Based on analytical and experimental results, in the full GPS coverage environment, the new tight integration CP method outperforms the INS-aided tight CP method, tight CP method, and DGPS by 11%, 15%, and 24%, respectively; in the GPS outage scenario, the performance improvement achieves 60%, 65%, and 73%, respectively.

  16. Growth differences of male and female Gottingen minipigs during ad libitum feeding: a pilot study

    DEFF Research Database (Denmark)

    Bollen, P.J.A.; Madsen, L.W.; Meyer, Otto A.;

    2005-01-01

    Even though minipigs have been used in biomedical research for nearly half a century now, no specific nutrient requirements are available. For that reason a series of studies into the nutrient requirements of Gottingen minipigs were carried out. Firstly, a pilot study was carried out to determine...

  17. Exposure to movie smoking, antismoking ads and smoking intensity: an experimental study with a factorial design

    NARCIS (Netherlands)

    Z. Harakeh; R.C.M.E. Engels; K. Vohs; R.B. van Baaren; J. Sargent

    2010-01-01

    Background This study examines whether smoking portrayal in movies or antismoking advertisements affect smoking intensity among young adults. Methods We conducted an experimental study in which 84 smokers were randomly assigned using a two (no-smoking versus smoking portrayal in the movie) by three

  18. Adding a design perspective to study learning environments in higher professional education

    NARCIS (Netherlands)

    Zitter, I.I.; De Bruijn, E.E.J.; Simons, P.R.J.; ten Cate, Th.J.

    2010-01-01

    How to design learning environments leading to learning-, thinking, collaboration- and regulation skills which can be applied to transferable, knowledge oriented learning outcomes is still controversial. We studied the designs of learning environments in innovative higher professional education more

  19. ENDING ON A HIGH NOTE: Adding a Better End to Effortful Study

    Science.gov (United States)

    Finn, Bridgid

    2010-01-01

    Remembered utility is the retrospective evaluation about the pleasure and pain associated with a past experience. It has been shown to influence prospective choices about whether to repeat or to avoid similar situations in the future (Kahneman 2000; Kahneman, Fredrickson, Schreiber & Redelmeier, 1993). Evaluations about our hedonic past often disregard the duration of the experience and are influenced more by the peak and the final levels of discomfort (Fredrickson & Kahneman, 1993). Two experiments explored the remembered discomfort of an effortful learning experience and the influence of this evaluation on prospective study choices. The design of the studies mimicked Kahneman et al.'s, (1993) cold-pressor study, but used an exceptionally challenging learning experience in place of the painful experience of submerging one's hand in ice water. An extremely effortful study episode extended by a more moderate interval was preferred to a shorter, unextended interval, despite better test performance following the shorter interval. Future study choices reflected this preference. These findings suggest that the act of acquiring knowledge has value in the learning process. PMID:20854005

  20. Viability study of photo-voltaic systems added to terrestrial electric vehicles

    Energy Technology Data Exchange (ETDEWEB)

    Rippel, W.E.

    1990-09-01

    The purpose of the following computer study is to determine the set of necessary conditions under which the addition of photo-voltaic (PV) cells to electric vehicles provides a net utility or economic benefit. Economic benefits are given the primary focus and are evaluated in terms of a payback period.

  1. Adding Qualitative and Mixed Methods Research to Health Intervention Studies: Interacting With Differences.

    Science.gov (United States)

    Johnson, R Burke; Schoonenboom, Judith

    2016-04-01

    The purpose of this article is to explain how to improve intervention designs, such as randomized controlled trials (RCTs), in health science research using a process philosophy and theory known as dialectical pluralism (DP). DP views reality as plural and uses dialectical, dialogical, and hermeneutical approaches to knowledge construction. Using DP and its "both/and" logic, and its attempt to produce new creative syntheses, researchers on heterogeneous teams can better dialogue with qualitative and mixed methods approaches, concepts, paradigms, methodologies, and methods to improve their intervention research studies. The concept of reflexivity is utilized but is expanded when it is a component of DP. Examples of strategies for identifying, inviting, and creating divergence and integrative strategies for producing strong mixed methods intervention studies are provided and illustrated using real-life examples. PMID:26657970

  2. Adding Qualitative and Mixed Methods Research to Health Intervention Studies: Interacting With Differences.

    Science.gov (United States)

    Johnson, R Burke; Schoonenboom, Judith

    2016-04-01

    The purpose of this article is to explain how to improve intervention designs, such as randomized controlled trials (RCTs), in health science research using a process philosophy and theory known as dialectical pluralism (DP). DP views reality as plural and uses dialectical, dialogical, and hermeneutical approaches to knowledge construction. Using DP and its "both/and" logic, and its attempt to produce new creative syntheses, researchers on heterogeneous teams can better dialogue with qualitative and mixed methods approaches, concepts, paradigms, methodologies, and methods to improve their intervention research studies. The concept of reflexivity is utilized but is expanded when it is a component of DP. Examples of strategies for identifying, inviting, and creating divergence and integrative strategies for producing strong mixed methods intervention studies are provided and illustrated using real-life examples.

  3. AN EXPERIMENTAL STUDY ON A VAPOR COMPRESSION REFRIGERATION CYCLE BY ADDING INTERNAL HEAT EXCHANGER

    OpenAIRE

    Muhammad Asmail Eleiwi

    2013-01-01

    Thispaper presents practical study to improve the indication COP of a vaporcompression refrigeration cycle in instrumented automobile air conditioner bydesigning internal heat exchanger and installing it in the vapor compressionrefrigeration cycle.  Two cases of  vapor compression refrigeration cycle were takenin this paper:  the first case is thatthe vapor compression refrigeration cycle without internal heat exchanger andin  the second case the vapor compressionrefrigeration cycle with heat...

  4. Understanding Video-Ad Consumption on YouTube: A Measurement Study on User Behavior, Popularity, and Content Properties

    OpenAIRE

    Arantes, Mariana; Figueiredo, Flavio; Almeida, Jussara M.

    2016-01-01

    Faced with the challenge of attracting user attention and revenue, social media websites have turned to video advertisements (video-ads). While in traditional media the video-ad market is mostly based on an interaction between content providers and marketers, the use of video-ads in social media has enabled a more complex interaction, that also includes content creator and viewer preferences. To better understand this novel setting, we present the first data-driven analysis of video-ad exhibi...

  5. Protein expression and preparation of polydonal antibody of AD-004 and study on its expression in the adrenal and testis

    Institute of Scientific and Technical Information of China (English)

    乔洁

    2006-01-01

    Objective To prepare rabbit antibody against mouse AD-004 by AD-004 expressed in the prokaryotic expression system and to identify its distribution in the testis and adrenal. Methods The full-length cDNA of mouse AD-004 was cloned into PET28 plasmid, and the protein was induced in E. coli BL21 bacteria by adding IPTG and then purified by Ni2+ -NTA column. The purified protein was used as an immunogene to prepare polyclonal

  6. Coopetitive Ad Auctions

    OpenAIRE

    Hoy, Darrell; Jain, Kamal; Wilkens, Christopher A.

    2012-01-01

    A single advertisement often benefits many parties, for example, an ad for a Samsung laptop benefits Microsoft. We study this phenomenon in search advertising auctions and show that standard solutions, including the status quo ignorance of mutual benefit and a benefit-aware Vickrey-Clarke-Groves mechanism, perform poorly. In contrast, we show that an appropriate first-price auction has nice equilibria in a single-slot ad auction --- all equilibria that satisfy a natural cooperative envy-freen...

  7. Dirac operator on fuzzy AdS2

    International Nuclear Information System (INIS)

    In this article we construct the chirality and Dirac operators on fuzzy AdS2. We also derive the discrete spectrum of the Dirac operator which is important in the study of the spectral triple associated to AdS2. It is shown that the degeneracy of the spectrum present in the commutative AdS2 is lifted in the noncommutative case. The way we construct the chirality operator is suggestive of how to introduce the projector operators of the corresponding projective modules on this space. (author)

  8. Dirac Operator on Noncommutative AdS_2

    CERN Document Server

    Fakhri, H

    2003-01-01

    In this article we construct the chirality and Dirac operators on noncommutative AdS_2. We also derive the discrete spectrum of the Dirac operator which is important in the study of the spectral triple associated with AdS_2. It is shown that the degeneracy of the spectrum present in the commutative AdS_2 is lifted in the noncommutative case. The way we construct the chirality operator is suggestive of how to introduce the projector operators of the corresponding projective modules on this space.

  9. Dirac operator on fuzzy AdS2

    Science.gov (United States)

    Fakhri, Hossein; Imaanpur, Ali

    2003-03-01

    In this article we construct the chirality and Dirac operators on noncommutative AdS2. We also derive the discrete spectrum of the Dirac operator which is important in the study of the spectral triple associated to AdS2. It is shown that the degeneracy of the spectrum present in the commutative AdS2 is lifted in the noncommutative case. The way we construct the chirality operator is suggestive of how to introduce the projector operators of the corresponding projective modules on this space.

  10. Dirac Operator on Fuzzy AdS_2

    OpenAIRE

    H. Fakhri; Imaanpur, A.

    2003-01-01

    In this article we construct the chirality and Dirac operators on noncommutative AdS_2. We also derive the discrete spectrum of the Dirac operator which is important in the study of the spectral triple associated with AdS_2. It is shown that the degeneracy of the spectrum present in the commutative AdS_2 is lifted in the noncommutative case. The way we construct the chirality operator is suggestive of how to introduce the projector operators of the corresponding projective modules on this space.

  11. Towards integrability for AdS3/CFT2

    CERN Document Server

    Sfondrini, Alessandro

    2014-01-01

    We review the recent progress towards applying worldsheet integrability techniques to the $AdS_3/CFT_2$ correspondence to find its all-loop S matrix and Bethe-Yang equations. We study in full detail the massive sector of $AdS_3\\times S^3\\times T^4$ superstrings supported by pure Ramond-Ramond (RR) fluxes. The extension of this machinery to accommodate massless modes, to the $AdS_3\\times S^3\\times S^3\\times S^1$ pure-RR background and to backgrounds supported by mixed background fluxes is also reviewed. While the results discussed here were found elsewhere, our exposition is original.

  12. AN EXPERIMENTAL STUDY ON A VAPOR COMPRESSION REFRIGERATION CYCLE BY ADDING INTERNAL HEAT EXCHANGER

    Directory of Open Access Journals (Sweden)

    Muhammad Asmail Eleiwi

    2013-05-01

    Full Text Available Thispaper presents practical study to improve the indication COP of a vaporcompression refrigeration cycle in instrumented automobile air conditioner bydesigning internal heat exchanger and installing it in the vapor compressionrefrigeration cycle.  Two cases of  vapor compression refrigeration cycle were takenin this paper:  the first case is thatthe vapor compression refrigeration cycle without internal heat exchanger andin  the second case the vapor compressionrefrigeration cycle with heat exchanger ; in these two cases, the temperatureat each point of  a vapor compressionrefrigeration cycle, the low and the high pressure ,the indoor temperature andthe outdoor temperature were measured at each time at compressor speed 1450 rpmand 2900 rpm for each blower speed 1, blower speed 2 and blower speed 3.Therefrigerant fluid was used in the vapor compression refrigeration cycle withoutIHE and with IHE is R134a..

  13. Lattice and string worldsheet in AdS/CFT: a numerical study

    CERN Document Server

    Forini, Valentina; Bianchi, Marco S; Leder, Björn; Vescovi, Edoardo

    2016-01-01

    We consider a possible discretization for the gauge-fixed Green-Schwarz (two-dimensional) sigma-model action for the Type IIB superstring and use it for measuring the cusp anomalous dimension of planar $\\mathcal{N}=4$ SYM as derived from string theory. We perform lattice simulations employing a Rational Hybrid Monte Carlo (RHMC) algorithm and a Wilson-like fermion discretization. In this preliminary study, we compare our results with the expected behavior for very large values of $g=\\frac{\\sqrt{\\lambda}}{4\\pi}$, which is the perturbative regime of the sigma-model, and find a qualitative agreement at finite lattice spacing. For smaller $g$ the continuum limit is obstructed by a divergence. We also detect a phase in the fermion determinant, whose origin we explain, which for small $g$ leads to a sign problem not treatable via standard reweigthing. Results presented here are discussed thoroughly in~\\cite{toappear}.

  14. International Programmes on ADS: ISTC

    International Nuclear Information System (INIS)

    The International Science and Technology Center (ISTC) is an intergovernmental organization, created to serve the goal of improving global safety and security. The European Union, Japan, the Russian Federation and the United States of America, on the basis of a multinational agreement, established ISTC in 1992. The ISTC focused its efforts on funding research projects related to key safety and security technologies including advanced nuclear technology. Since the first ISTC funded project in 1994, Accelerator Driven Systems, Transmutation research and a holistic approach to the nuclear fuel cycle were the areas where ISTC made a real impact on international development in these fields. Given the international dimension of the problem, the research communities of the ISTC member states quickly realized that ISTC projects offered a very flexible and fruitful cooperation platform to address many difficult issues of the nuclear fuel cycle. Highly competent expert communities of ISTC member states benefited from a well defined and transparent mode of operation of ISTC and objective oriented project funding strategy. The ISTC projects related to transmutation of radioactive waste and ADS can be classified in the following thematic areas: - ADS concepts; - Accelerator development; - Spallation target studies; - Nuclear data and spallation process studies; - Minor actinides studies related to ADS; - Partitioning and extraction

  15. A study on development of value added technology of pyrophyllite and dickite

    Energy Technology Data Exchange (ETDEWEB)

    Cho, Keon-Joon; Choi, Yeon-Ho; Kim, Sang-Bae; Jeon, Ho-Seok; Cho, Sung-Baek [Korea Institute of Geology Mining and Materials, Taejon (Korea, Republic of)

    1997-12-01

    Pyrophyllite and dickite have being utilized as refractories, ceramics, cement, fiber glass, paper, rubber, paints etc.. However, there are not any domestic companies to produce fillers of pyrophyllite and dickite for plastic and rubber. Moreover, several kinds of fillers are imported every year with expensive price for plastic and rubber filler. This study has purpose to develop manufacturing technologies to produce fillers for plastic and rubber of pyrophyllite and dickite. The chemical and mineralogical properties of samples, the optimum grinding condition and device for producing plastic fillers and development of technology of improvement in whiteness, and the optimum synthesis condition of zeolite Y are the scopes and contents of the study. Pyrophyllite samples are taken from Bunam. Principal composed minerals are pyrophyllite, quartz and dickite, having chemical components of 9.2% Al{sub 2}O{sub 3}, 74.8% SiO{sub 2}, and 0.1% Fe{sub 2}O{sub 3}, respectively. Dickite sample is taken from Bugok, consists of dickite and quartz having 37.7% Al{sub 2}O{sub 3}, 47.8% SiO{sub 2} and 0.04% Fe{sub 2}O{sub 3}. Efficiency of the vibrating mill proved to be greater than ball mill compare with median size. The whiteness of sample increased with roasting temperature. In grinding a Bunam and Bugok sample by vibrating mill for 180 minute, median particle size is 3.06{mu}m and 2.85{mu}m, respectively. The structure water dehydration temperature is about 600 deg.C and mullite is presented around 850 deg.C for dickite, and the whiteness increased with roasting temperature. The whiteness of Bunam and Bugok sample ground by vibrating mill for 180 minute and roasted for 60 minutes at 900 deg.C is 96.5, 98, respectively. The mole ratio of SiO{sub 2}/Al{sub 2}O{sub 3} is important factor for synthesis of zeolite Y, crystallinity is 56 at SiO{sub 2}/Al{sub 2}O{sub 3} mole ratio is 13. Reaction time also important factor, crystallinity is 52 at SiO{sub 2}/Al{sub 2}O{sub 3} mole ratio

  16. Th and U fuel photofission study by NTD for AD-MSR subcritical assembly

    International Nuclear Information System (INIS)

    During the last decade a considerable effort has been devoted for developing energy generating systems based on advanced nuclear technology within the design concepts of GEN-IV. Thorium base fuel systems such as accelerator driven nuclear reactors are one of the often mentioned attractive and affordable options. Several radiotherapy linear accelerators are on the market and due to their reliability, they could be employed as drivers for subcritical liquid fuel assemblies. Bremsstrahlung photons with energies above 5.5MeV, induce (γ,n) and (e,e’n) reactions in the W-target. Resulting gamma radiation and photo or fission neutrons may be absorbed in target materials such as thorium and uranium isotopes to induce sustained fission or nuclear transmutation in waste radioactive materials. Relevant photo driven and photo-fission reaction cross sections are important for actinides 232Th, 238U and 237Np in the radiotherapy machines energy range of 10-20 MV. In this study we employ passive nuclear track detectors (NTD) to determine fission rates and neutron production rates with the aim to establish the feasibility for gamma and photo-neutron driven subcritical assemblies. To cope with these objectives a 20 MV radiotherapy machine has been employed with a mixed fuel target. Results will support further development for a subcritical assembly employing a thorium containing liquid fuel. It is expected that acquired technological knowledge will contribute to the Venezuelan nuclear energy program

  17. Th and U fuel photofission study by NTD for AD-MSR subcritical assembly

    Energy Technology Data Exchange (ETDEWEB)

    Sajo-Bohus, Laszlo; Greaves, Eduardo D.; Barros, Haydn; Pino, Felix; Barrera, Maria T.; Farina, Fulvio [Universidad Simón Bolívar, Nuclear Physics Laboratory, Apdo 89000, Caracas 1080A (Venezuela, Bolivarian Republic of); Davila, Jesus [Física Médica C. A. and Universidad Central de Venezuela, Caracas (Venezuela, Bolivarian Republic of)

    2015-07-23

    During the last decade a considerable effort has been devoted for developing energy generating systems based on advanced nuclear technology within the design concepts of GEN-IV. Thorium base fuel systems such as accelerator driven nuclear reactors are one of the often mentioned attractive and affordable options. Several radiotherapy linear accelerators are on the market and due to their reliability, they could be employed as drivers for subcritical liquid fuel assemblies. Bremsstrahlung photons with energies above 5.5MeV, induce (γ,n) and (e,e’n) reactions in the W-target. Resulting gamma radiation and photo or fission neutrons may be absorbed in target materials such as thorium and uranium isotopes to induce sustained fission or nuclear transmutation in waste radioactive materials. Relevant photo driven and photo-fission reaction cross sections are important for actinides {sup 232}Th, {sup 238}U and {sup 237}Np in the radiotherapy machines energy range of 10-20 MV. In this study we employ passive nuclear track detectors (NTD) to determine fission rates and neutron production rates with the aim to establish the feasibility for gamma and photo-neutron driven subcritical assemblies. To cope with these objectives a 20 MV radiotherapy machine has been employed with a mixed fuel target. Results will support further development for a subcritical assembly employing a thorium containing liquid fuel. It is expected that acquired technological knowledge will contribute to the Venezuelan nuclear energy program.

  18. Th and U fuel photofission study by NTD for AD-MSR subcritical assembly

    Science.gov (United States)

    Sajo-Bohus, Laszlo; Greaves, Eduardo D.; Davila, Jesus; Barros, Haydn; Pino, Felix; Barrera, Maria T.; Farina, Fulvio

    2015-07-01

    During the last decade a considerable effort has been devoted for developing energy generating systems based on advanced nuclear technology within the design concepts of GEN-IV. Thorium base fuel systems such as accelerator driven nuclear reactors are one of the often mentioned attractive and affordable options. Several radiotherapy linear accelerators are on the market and due to their reliability, they could be employed as drivers for subcritical liquid fuel assemblies. Bremsstrahlung photons with energies above 5.5MeV, induce (γ,n) and (e,e'n) reactions in the W-target. Resulting gamma radiation and photo or fission neutrons may be absorbed in target materials such as thorium and uranium isotopes to induce sustained fission or nuclear transmutation in waste radioactive materials. Relevant photo driven and photo-fission reaction cross sections are important for actinides 232Th, 238U and 237Np in the radiotherapy machines energy range of 10-20 MV. In this study we employ passive nuclear track detectors (NTD) to determine fission rates and neutron production rates with the aim to establish the feasibility for gamma and photo-neutron driven subcritical assemblies. To cope with these objectives a 20 MV radiotherapy machine has been employed with a mixed fuel target. Results will support further development for a subcritical assembly employing a thorium containing liquid fuel. It is expected that acquired technological knowledge will contribute to the Venezuelan nuclear energy program.

  19. Rigid Holography and Six-Dimensional N=(2,0) Theories on AdS_5 times S^1

    CERN Document Server

    Aharony, Ofer; Rey, Soo-Jong

    2015-01-01

    Field theories on anti-de Sitter (AdS) space can be studied by realizing them as low-energy limits of AdS vacua of string/M theory. In an appropriate limit, the field theories decouple from the rest of string/M theory. Since these vacua are dual to conformal field theories (CFTs), this relates some of the observables of these field theories on AdS to a subsector of the dual CFTs. We exemplify this `rigid holography' by studying in detail the 6d N=(2,0) A_{K-1} superconformal field theory (SCFT) on AdS_5xS^1, with equal radii for AdS_5 and for S^1. We choose specific boundary conditions preserving sixteen supercharges that arise when this theory is embedded into Type IIB string theory on AdS_5xS^5/Z_K. On R^{4,1}xS^1, this 6d theory has a 5(K-1)-dimensional moduli space, with unbroken 5d SU(K) gauge symmetry at (and only at) the origin. On AdS_5xS^1, the theory has a 2(K-1)-dimensional `moduli space' of supersymmetric configurations. We argue that in this case the SU(K) gauge symmetry is unbroken everywhere in...

  20. ADS National Programmes: Netherlands

    International Nuclear Information System (INIS)

    The ADS related activities within the Netherlands are concentrated at NRG. From 2000 to 2006, NRG supported SCK•CEN in their development of MYRRHA. The support was mainly devoted to Computational Fluid Dynamics (CFD) simulations for the windowless target option. This collaboration was prolonged within the framework of the EU FP6 EUROTRANS project. Eventually this lead to a solution strategy for the hydraulic (without heat transfer) evaluation of a windowless target with one free surface using an Eulerian-Eulerian modeling approach. As a second free surface was added to the target design later, this approach would need to be revisited. The developed approach was applied to an assess the feasibility of a three feeder windowless target design. This preliminary assessment confirmed that there were no serious show stoppers for a three feeder design. Another study undertaken using related to the windowless target was a preliminary assessment of the risk of lead-bismuth splashing in case of a sudden heat deposition by the beam, e.g. at beam startup or beam interuptions. Within the framework of the EU FP7 CDT project, a window target is currently being assessed thermalhydraulicly in collaboration with SCK•CEN. Within the EU FP5 ASCHLIM project, the state of the art with regard to turbulence modelling for CFD approaches was determined. It was concluded that accurate simulation of heat transport in HLM was not feasible, especially in natural or mixed convection regimes. Within the EU FP7 THINS project this issue is currently being treated. NRG assists the commercial CFD code vendor CD adapco in implementing and testing a promising, academically tested, algebraic heat flux model

  1. Nuclear data requirements for the ADS conceptual design EFIT: Uncertainty and sensitivity study

    Energy Technology Data Exchange (ETDEWEB)

    Garcia-Herranz, N., E-mail: nuria@din.upm.e [Departamento de Ingenieria Nuclear, Universidad Politecnica de Madrid (Spain); Instituto de Fusion Nuclear, Universidad Politecnica de Madrid (Spain); Cabellos, O. [Departamento de Ingenieria Nuclear, Universidad Politecnica de Madrid (Spain); Instituto de Fusion Nuclear, Universidad Politecnica de Madrid (Spain); Alvarez-Velarde, F. [CIEMAT (Spain); Sanz, J. [Instituto de Fusion Nuclear, Universidad Politecnica de Madrid (Spain); Departamento de Ingenieria Energetica, UNED (Spain); Gonzalez-Romero, E.M. [CIEMAT (Spain); Juan, J. [Laboratorio de Estadistica, Universidad Politecnica de Madrid (Spain)

    2010-11-15

    In this paper, we assess the impact of activation cross-section uncertainties on relevant fuel cycle parameters for a conceptual design of a modular European Facility for Industrial Transmutation (EFIT) with a 'double strata' fuel cycle. Next, the nuclear data requirements are evaluated so that the parameters can meet the assigned design target accuracies. Different discharge burn-up levels are considered: a low burn-up, corresponding to the equilibrium cycle, and a high burn-up level, simulating the effects on the fuel of the multi-recycling scenario. In order to perform this study, we propose a methodology in two steps. Firstly, we compute the uncertainties on the system parameters by using a Monte Carlo simulation, as it is considered the most reliable approach to address this problem. Secondly, the analysis of the results is performed by a sensitivity technique, in order to identify the relevant reaction channels and prioritize the data improvement needs. Cross-section uncertainties are taken from the EAF-2007/UN library since it includes data for all the actinides potentially present in the irradiated fuel. Relevant uncertainties in some of the fuel cycle parameters have been obtained, and we conclude with recommendations for future nuclear data measurement programs, beyond the specific results obtained with the present nuclear data files and the limited available covariance information. A comparison with the uncertainty and accuracy analysis recently published by the WPEC-Subgroup26 of the OECD using BOLNA covariance matrices is performed. Despite the differences in the transmuter reactor used for the analysis, some conclusions obtained by Subgroup26 are qualitatively corroborated, and improvements for additional cross sections are suggested.

  2. Identifying the types of waves: A value adding study on the ocean observing data buoy system

    Science.gov (United States)

    Ramakrishnan, B.; Sannasiraj, S.; Sundar, V.

    2007-05-01

    Understanding of the wave climate in a particular place of interest is one of the primary aspects of any ocean observing system. Engineers and scientists working in the area of coastal or offshore engineering require to have knowledge on the types of waves that predominantly prevailing not only for the design of the ocean structures but also to understand the physical behavior of ocean surface. For example, identification of breaking waves is given prime importance as it has potential to answer for many of the water-air interaction or turbulence mixing problems. On the other hand, group of waves in which successive wave heights exceed the significant value could exert tremendous forces on the ocean structures and may lead catastrophic damage to it. Apart from deriving the conventional information such as the significant wave periods, heights and the predominant direction of prevailing, knowledge on the existence of type of waves would certainly help the designers, engineers and researchers. In an attempt to classify the types of waves from the buoy measurements, a detailed experimental program was conducted in the Department of Ocean Engineering, Indian Institute of Technology Madras. The buoy model was subjected to variety of waves such as group and breaking waves. The challenging task of the study is to simulate the group and breaking waves in the controlled laboratory environment. For which, initially, these waves are simulated theoretically, which intern converted into first order wave paddle signals to simulate the waves in the flume. The buoy heave, surge and pitch motions were measured by using potentiometers and the non-contact motion capturing cameras. The experimentally obtained wave elevation and the buoy motions time histories were analyzed by statistical, continuous wavelet transformation and phase-time methods to find the traces of wave types. A careful step by step analysis of the buoy motions yields presence of wave groupiness and breaking events

  3. Symmetries of the Boundary of $AdS_{5} \\times S^{5}$ and Harmonic Superspace

    CERN Document Server

    Claus, P; Rahmfeld, J; Claus, Piet; Kallosh, Renata

    1999-01-01

    We study the boundary limit of the bulk isometries of AdS x S. The superconformal symmetry is realized on the coordinates of the AdS boundary, the fermionic superspace coordinates, and the harmonics on the sphere. We show how these may be related to the coordinates of an off-shell harmonic superspace of SCFT living on the boundary. In the special case of d=4, N=2 super Yang-Mills theory, a truncation of the N=4 SYM dual to Type IIB string theory compactified on AdS_5 x S^5, we identify the bosonic space $SU(2)/U(1)$ of the N=2 harmonic superspace (known before as auxiliary) with the S^2 submanifold of the S^5.

  4. Study of the fuel behavior, safety characteristics and transmutation performance of a gas cooled accelerator driven system (ADS)

    International Nuclear Information System (INIS)

    The neutronic behavior of an ADS system based on gas cooling is examined in this work by using the simulation tools MCNPX and ORIGEN. The main character of the MCNPX code is the use of the Monte-Carlo method allowing a high dimensional simulation of the physical processes. The whole model of the core is represented in 3 dimensional zones including the target structure, which provides the initial spallation neutrons for the chain reaction in the fuel zone. At the beginning, MOX fuel with 19.5 wt. Pu/(Pu+U) is loaded in order to investigate the technical feasibility of a test facility. The fuel assemblies are replaced step by step with Plutonium and minor actinides (PuMa) uranium free fuel according to a loading and shuffling pattern. The designed test facility consists of 120 fuel assemblies each 91 fuel rods which are arranged around the spallation target. For a thermal power of 100 MW the burn-up and transmutation rate is studied. The first results for the MOX and partially PuMa fuel loaded core are presented in this paper. For the PuMa fuel two compositions are investigated. Both fuel types chosen for the analysis demonstrate the capability of the incineration of americium. The simulations show that the initial composition has significant influence on the transmutation rate. The deployment of MOX type fuel in the ADS core causes a considerable consumption of Pu but also a significant generation of americium

  5. Feasibility study for adding a demand failure data collection system to the Nuclear Plant Reliability Data System. Final report

    International Nuclear Information System (INIS)

    Southwest Research Institute (SwRI) is pleased to submit to Sandia National Laboratories this technical report as fulfillment of Task 5 of the proposal entitled A Feasibility Study for Adding a Duty Cycle Data Collection System to the Nuclear Plant Reliability Data System. The purpose of this report is to summarize the work as delineated in the proposal tasks and to recommend follow-on activities. Technical support for this work was provided by Duke Power Company (Duke), subcontractor to SwRI. The four tasks to be performed in conjunction with the Duty Cycle Data Collection Study (renamed in this report Demand Data Collection) were: define component population and measurable parameters; develop data collection and assessment methodologies; assess the impact on utilities; and assess the impact on NPRDS

  6. Penrose inequality for asymptotically AdS spaces

    Energy Technology Data Exchange (ETDEWEB)

    Itkin, Igor [Raymond and Beverly Sackler School of Physics and Astronomy, Tel-Aviv University, Tel-Aviv 69978 (Israel); Oz, Yaron, E-mail: yaronoz@post.tau.ac.il [Raymond and Beverly Sackler School of Physics and Astronomy, Tel-Aviv University, Tel-Aviv 69978 (Israel)

    2012-02-28

    In general relativity, the Penrose inequality relates the mass and the entropy associated with a gravitational background. If the inequality is violated by an initial Cauchy data, it suggests a creation of a naked singularity, thus providing means to consider the cosmic censorship hypothesis. We propose a general form of Penrose inequality for asymptotically locally AdS spaces.

  7. Global geometric properties of AdS space and the AdS/CFT correspondence

    Institute of Scientific and Technical Information of China (English)

    2001-01-01

    The Poisson kernels and relations between them for a massive scalar field in a unit ball Bn with Hua's metric and conformal flat metric are obtained by describing the Bn as a submanifold of an (n+1)-dimensional embedding space. Global geometric properties of the AdS space are discussed. We show that the(n+1)-dimensional AdS space AdSn+1 is isomorphic to RP1×Bn and boundary of the AdS is isomorphic to RP1×Sn-1. Bulk-boundary propagator and the AdS/CFT like correspondence are demonstrated based on these global geometric properties of the RP1×Bn.

  8. AdS-Carroll Branes

    CERN Document Server

    Clark, T E

    2016-01-01

    Coset methods are used to determine the action of a co-dimension one brane (domain wall) embedded in (d+1)-dimensional AdS space in the Carroll limit in which the speed of light goes to zero. The action is invariant under the non-linearly realized symmetries of the AdS-Carroll spacetime. The Nambu-Goldstone field exhibits a static spatial distribution for the brane with a time varying momentum density related to the brane's spatial shape as well as the AdS-C geometry. The AdS-C vector field dual theory is obtained.

  9. Added Responsibilities

    Institute of Scientific and Technical Information of China (English)

    2010-01-01

    Historic monuments in Dengfeng,formally referred to as the Center of Heaven and Earth,in Henan Province,as well as Danxia Landform in several southern and eastern Chinese provinces,were proclaimed UNESCO world heritage sites recently. The group of constructions in Dengfeng includes some of the best examples of ancient Chinese buildings devoted to rituals,science,technology and education. Most of the constructions present vividly a history of central China’s architecture from the last 2,000 years and contain very valuable material for studies.

  10. Shapes related to longitudinal studies of disease

    DEFF Research Database (Denmark)

    Erleben, Lene Lillemark

    This dissertation investigates novel markers for cardiovascular diseases (CVD) and Alzheimer's disease (AD). Both CVD and AD are among the large diseases counted in morbidity and mortality in the western world, which makes them huge and increasing problems. By investigating and learning character...

  11. Constructing the AdS dual of a Fermi liquid: AdS Black holes with Dirac hair

    CERN Document Server

    \\vCubrović, Mihailo; Schalm, Koenraad

    2010-01-01

    We provide new evidence that the holographic dual to a strongly coupled charged Fermi Liquid has a non-zero fermion density in the bulk. We show that the pole-strength of the stable quasiparticle characterizing the Fermi surface is encoded in the spatially averaged AdS probability density of a single normalizable fermion wavefunction in AdS. Recalling Migdal's theorem which relates the pole strength to the Fermi-Dirac characteristic discontinuity in the number density at $\\ome_F$, we conclude that the AdS dual of a Fermi liquid is described by occupied on-shell fermionic modes in AdS. Encoding the occupied levels in the total probability density of the fermion field directly, we show that an AdS Reissner-Nordstr\\"{o}m black hole in a theory with charged fermions has a critical temperature, at which the system undergoes a first-order transition to a black hole with a non-vanishing profile for the bulk fermion field. Thermodynamics and spectral analysis confirm that the solution with non-zero AdS fermion-profil...

  12. Phase transition and thermodynamical geometry for Schwarzschild AdS black hole in $AdS_5\\times{S^5}$ spacetime

    CERN Document Server

    Zhang, Jia-Lin; Yu, Hongwei

    2014-01-01

    We study thermodynamics and thermodynamic geometry of a five-dimensional Schwarzschild AdS black hole in $AdS_5\\times{S^5}$ spacetime by treating the cosmological constant as the number of colors in the boundary gauge theory and its conjugate quantity as the associated chemical potential. It is found that the chemical potential is always negative in the stable branch of black hole thermodynamics and it has a chance to be positive, but appears in the unstable branch. We calculate scalar curvatures of the thermodynamical Weinhold metric, Ruppeiner metric and Quevedo metric, respectively and we find that the divergence of scalar curvature is related to the divergence of specific heat with fixed chemical potential in the Weinhold metric and Ruppeiner metric, while in the Quevedo metric the divergence of scalar curvature is related to the divergence of specific heat with fixed number of colors and the vanishing of the specific heat with fixed chemical potential.

  13. Is anti-doping analysis so far from clinical, legal or forensic targets?: The added value of close relationships between related disciplines.

    Science.gov (United States)

    Segura, Jordi

    2009-11-01

    There are many areas of common interest between anti-doping laboratories and those working in the clinical, legal and forensic fields. In addition to methodological similarities, there are aspects of the findings in sport drug testing that overlap with other fields in such a way that sport drug testing and clinical, legal or forensic work may benefit from mutual interaction. Three recent examples are presented from the author's experience. Case report 1 concerns the clinical relevance of hCG findings in sport drug testing as potential indicators of the presence of a (testicular) tumour in athletes. Case report 2 refers to difficulties that accredited laboratories can encounter due to differences between national legal systems and the administrative regulation systems of sport authorities. The example involves a network of blood collection for further autologous transfusion. Case report 3 relates to additional forensic-type investigations needed to interpret a situation where intoxication of a whole delegation was responsible for apparent doping cases. Clinical, legal and forensic fields must recognize the added value that some results and developments coming from anti-doping laboratories may have. At the same time anti-doping analysts should be aware of new issues, methodologies and problems appearing in related fields.

  14. Online Ad Assignment with an Ad Exchange

    OpenAIRE

    Dvořák, Wolfgang; Henzinger, Monika

    2016-01-01

    Ad exchanges are becoming an increasingly popular way to sell advertisement slots on the internet. An ad exchange is basically a spot market for ad impressions. A publisher who has already signed contracts reserving advertisement impressions on his pages can choose between assigning a new ad impression for a new page view to a contracted advertiser or to sell it at an ad exchange. This leads to an online revenue maximization problem for the publisher. Given a new impression to sell decide whe...

  15. On the use of Bayesian networks to combine raw data from related studies on sensory satiation

    NARCIS (Netherlands)

    Phan, V.A.; Ramaekers, M.G.; Bolhuis, D.P.; Garczarek, U.; Boekel, van M.A.J.S.; Dekker, M.

    2012-01-01

    Bayesian networks were used to combine raw datasets from two independently performed but related studies. Both studies investigated sensory satiation by measuring ad libitum intake of a tomato soup model. The Aroma study varied aroma concentration and aroma duration as the explanatory variables, and

  16. Child AD/HD Severity and Psychological Functioning in Relation to Divorce, Remarriage, Multiple Transitions and the Quality of Family Relationships

    Science.gov (United States)

    Heckel, Leila; Clarke, Adam R.; Barry, Robert J.; McCarthy, Rory; Selikowitz, Mark

    2013-01-01

    Both Attention-Deficit/Hyperactivity Disorder (AD/HD) and divorce are very prevalent in western societies, and they may occur together. AD/HD is generally viewed as a neurobiological disorder, which has led to a commonly held belief that social-environmental factors play little role in the symptom profile of children diagnosed with the disorder.…

  17. Monopoles in AdS

    CERN Document Server

    Sutcliffe, Paul

    2011-01-01

    Applications to holographic theories have led to some recent interest in magnetic monopoles in four-dimensional Anti-de Sitter spacetime. This paper is concerned with a study of these monopoles, using both analytic and numerical methods. An approximation is introduced in which the fields of a charge N monopole are explicitly given in terms of a degree N rational map. Within this approximation, it is shown that the minimal energy monopole of charge N has the same symmetry as the minimal energy Skyrmion with baryon number N in Minkowski spacetime. Beyond charge two the minimal energy monopole has only a discrete symmetry, which is often Platonic. The rational map approximation provides an upper bound on the monopole energy and may be viewed as a smooth non-abelian refinement of the magnetic bag approximation, to which it reverts under some additional approximations. The analytic results are supported by numerical solutions obtained from simulations of the non-abelian field theory. A similar analysis is performe...

  18. Ultrasonic Elastography Research Based on a Multicenter Study: Adding Strain Ratio after 5-Point Scoring Evaluation or Not.

    Directory of Open Access Journals (Sweden)

    Wen-Jie Mu

    Full Text Available This study aimed to confirm whether strain ratio should be added after evaluation of lesions with 5-point elasticity scoring for differentiating benign and malignant breast lesions on ultrasonographic elastography(UE.From June 2010 to March 2012, 1080 consecutive female patients with breast lesions were recruited into a multicenter retrospective study, which involved 8 centers across China. Each institutional ethic review board approved the study, and all the patients gave written informed consent. All the patients underwent the UE procedure and the strain ratios were calculated and the final diagnosis was made by histological findings. The sensitivity, specificity, accuracy, PPV and NPV were calculated for each of the two evaluation systems and the areas under the ROC curve were compared.The strain ratios of benign lesions (mean, 2.6±2.0 and malignant lesions (mean,7.9±5.8 were significantly different (p 0.05. The strain ratio method shows better a diagnosis performance of the lesions with elasticity score 3 and 4.Although the two UE methods have similar diagnostic performance, separate calculation of the strain ratios seems compulsory, especially for the large solid breast lesions and the lesions with elasticity score 3 and 4.

  19. Ultrasonic Elastography Research Based on a Multicenter Study: Adding Strain Ratio after 5-Point Scoring Evaluation or Not

    Science.gov (United States)

    Yao, Ji-Yi; Li, Lu-Jing; Peng, Yu-lan; Wang, Yi; Liu, Li-sha; Xiao, Ying; Liu, Shou-jun; Wu, Chang-jun; Jiang, Yu-xin; Parajuly, Shyam Sundar; Xu, Ping; Hao, Yi; Li, Jing; Luo, Bao-Ming; Zhi, Hui

    2016-01-01

    Background This study aimed to confirm whether strain ratio should be added after evaluation of lesions with 5-point elasticity scoring for differentiating benign and malignant breast lesions on ultrasonographic elastography(UE). Materials and Methods From June 2010 to March 2012, 1080 consecutive female patients with breast lesions were recruited into a multicenter retrospective study, which involved 8 centers across China. Each institutional ethic review board approved the study, and all the patients gave written informed consent. All the patients underwent the UE procedure and the strain ratios were calculated and the final diagnosis was made by histological findings. The sensitivity, specificity, accuracy, PPV and NPV were calculated for each of the two evaluation systems and the areas under the ROC curve were compared. Results The strain ratios of benign lesions (mean, 2.6±2.0) and malignant lesions (mean,7.9±5.8) were significantly different (p 0.05). The strain ratio method shows better a diagnosis performance of the lesions with elasticity score 3 and 4. Conclusions Although the two UE methods have similar diagnostic performance, separate calculation of the strain ratios seems compulsory, especially for the large solid breast lesions and the lesions with elasticity score 3 and 4. PMID:26863208

  20. ADS National Programmes: Italy

    International Nuclear Information System (INIS)

    Following a preliminary design developed in 1998, based on the Energy Amplifier concept proposed by CERN, a first configuration of a lead-bismuth Eutectic cooled Experimental ADS (LBE-XADS) was worked out in the period 1999–2001, under the aegis of MURST, by a group of Italian organizations led by Ansado Nucleare, with the aim of assessing the feasibility of a small sized (80 MWth) ADS. At the end of 1997 a joint effort of ENEA (National Agency for New Technology, Energy and the Environment) and INFN (National Institute for Nuclear Physics) led to the approval of a national programme by MURST (Minister for University and Scientific and Technological Research) named TRASCO (TRAsmutazione SCOrie) aiming at the study of physics and technologies needed to design an ADS for radioactive waste transmutation. The programme consisted of research subprogrammes on accelerator, neutronics, thermalhydraulics analysis, beam window technology, and material technology and compatibility with Pb and Pb-Bi. At now, most of the activities in support to the ADS development carried out at national level are part of EU-funded Projects. These activities are complemented by the programme agreement (AdP -Accordo di programma), signed between ENEA and the Ministry of Economic Development, which provides in general a range of activities aimed at the development of sustainable nuclear fission systems. Several universities and the national industry are involved, besides ENEA, in the activities

  1. Neuroimaging basis in the conversion of aMCI patients with APOE-ε4 to AD: study protocol of a prospective diagnostic trial

    OpenAIRE

    Chen, Guan-Qun; Sheng, Can; Li, Yu-Xia; Yu, Yang; Wang, Xiao-Ni; SUN, Yu; Li, Hong-Yan; Li, Xuan-Yu; Xie, Yun-Yan; Han, Ying

    2016-01-01

    Background The ε4 allele of the Apolipoprotein E gene (APOE-ε4) is a potent genetic risk factor for sporadic Alzheimer’s disease (AD). Amnestic mild cognitive impairment (aMCI) is an intermediate state between normal cognitive aging and dementia, which is easy to convert to AD dementia. It is an urgent problem in the field of cognitive neuroscience to reveal the conversion of aMCI-ε4 to AD. Based on our preliminary work, we will study the neuroimaging features in the special group of aMCI-ε4 ...

  2. A study of the risk for Alzheimer’s disease in first-degree relatives of patients with affective disorders

    Institute of Scientific and Technical Information of China (English)

    徐文炜

    2013-01-01

    Objective To investigate the prevalence of Alzheimer’s disease (AD) in first-degree relatives of patients with affective disorders,and to evaluate the risk of AD in firstdegree relatives of the patients with affective disorders.Methods Patients with affective disorders meeting"DSM-Ⅳ-TR"criteria (affective disorders group) and their healthy spouses (conrol group) were recruited in this study (n=109 each) .The first-degree relatives in-

  3. CT-based Evaluation of Axillary Sentinel Lymph Node Status in Breast Cancer: Value of Added Contrast-Enhanced Study

    Energy Technology Data Exchange (ETDEWEB)

    Yuen, S.; Yamada, K.; Goto, M.; Sawai, K.; Nishimura, T. [Graduate School of Medical Science Kyoto Prefectural Univ. of Medicine (Japan). Dept. of Radiology and Dept. of Breast and Endocrine Surgery

    2004-11-01

    Purpose: To evaluate the diagnostic reliability of CT-based sentinel lymph node (SLN) size criteria for selecting the candidates for direct axillary dissection without SLN biopsy and to determine the value of added contrast-enhanced study. Material and Methods: Breast cancer patients (n=107) underwent triple phasic (1-min, 3-min, 8-min) contrast-enhanced 5 mm-computed tomography (CT) of the breasts and axillae. In the CT image, the most inferior lymph node in the axilla was designated the SLN. Axillary status was judged based on SLN size criteria. CT density, enhancement rate, and peak enhancement time of each SLN were correlated with histopathological results. Results: SLN size criteria demonstrated a sensitivity of 76% and a positive predictive value of 95% in predicting SLN metastasis. The density values at each scanning time-point were significantly different for metastatic and non-metastatic SLN. However, their enhancement rates differed significantly only at 1 min. Their peak enhancement occurred primarily at 1 min. The use of contrast-enhancement criteria improved the predictive sensitivity, but failed to decrease the false-positive rate of the SLN size criteria. Conclusion: The enhancement rate at 1 min proved to be the most useful parameter in contrast-enhanced CT studies; however, it failed in improving the accuracy of the SLN size criteria.

  4. Optimization studies of photo-neutron production in high- metallic targets using high energy electron beam for ADS and transmutation

    Indian Academy of Sciences (India)

    V C Petwal; V K Senecha; K V Subbaiah; H C Soni; S Kotaiah

    2007-02-01

    Monte Carlo calculations have been performed using MCNP code to study the optimization of photo-neutron yield for different electron beam energies impinging on Pb, W and Ta cylindrical targets of varying thickness. It is noticed that photo-neutron yield can be increased for electron beam energies ≥ 100 MeV for appropriate thickness of the target. It is also noticed that it can be maximized by further increasing the thickness of the target. Further, at higher electron beam energy heat gradient in the target decreases, which facilitates easier heat removal from the target. This can help in developing a photo-neutron source based on electron LINAC by choosing appropriate electron beam energy and target thickness to optimize the neutron flux for ADS, transmutation studies and as high energy neutron source etc. Photo-neutron yield for different targets, optimum target thickness and photo-neutron energy spectrum and heat deposition by electron beam for different incident energy is presented.

  5. Studies on low-carrier radiofluorination of non-active aromatics with no-carrier-added [18F]fluoride

    International Nuclear Information System (INIS)

    In vivo imaging with positron emission tomography generally demands radiotracers with a high specific activity. In case of fluorine-18 the required no-carrier-added (n.c.a.) starting material is only available in form of fluoride. This and the short half-life of 109.7 minutes of the radionuclide lead to the demand of special methods for radiosyntheses. The only practical procedure for manufacturing n.c.a. [18F]fluoro-compounds is therefore nucleophilic substitution. There is, however, still a lack of effective procedures for the labelling of electron rich aromatic molecules starting from n.c.a. [18F]fluoride. A process for n.c.a. radiofluorination of these compounds is offered by the reaction of iodonium compounds as starting materials. In this study modern procedures for the synthesis of iodoniumsalts and -ylides were investigated. Several precursor molecules for the versatile synthetic building block 4-[18F]fluoroiodobenzene were synthesised. In this course, a new one-pot procedure for the synthesis of iodoniumylides was developed. Further on, the syntheses of suitable iodonium precursors for two fluorophenoxy-derivatives, which are possible antidepressants, were investigated. Due to their binding profile these compounds can be considered as ligands for the serotonin reuptake transporter (SERT) and the norepinephrin reuptake transporter (NET), respectively. The preparation of appropriate iodonium salts proved to be too problematic, while the synthesis of suitable iodoniumylides could be accomplished with satisfactory yields of about 30% and 40 %, respectively. Both compounds were labelled with n.c.a. [18F]fluoride and deprotected to the desired target compounds 4-((3-[18F]fluorophenoxy)(phenyl)methyl)piperidine and 4-((4-[18F]fluorophenoxy)(phenyl)methyl)piperidine in radiochemical yields of about 40 % and 25 %, respectively. Those are now available for preclinical evaluation studies. Furthermore, a process for the palladium catalysed synthesis of 18F

  6. ADS National Programmes: Belgium

    International Nuclear Information System (INIS)

    The Belgian activities in the field of Accelerator Driven Systems (ADS) are mainly related to the MYRRHA project development. MYRRHA is an accelerator driven, multi purpose fast neutron spectrum facility for R&D, cooled by a lead-bismuth eutectic. SCK•CEN has started the MYRRHA project as a national programme with several national & international bilateral collaboration agreements; the project has now evolved as an European integrated project in the frame of the IPEUROTRANS (European Commission, Sixth Framework Programme). The MYRRHA ‘Draft-2’ predesign file (completed in the early 2005) has been proposed to the partners as a basis for the XT-ADS machine. After a detailed investigation of potential alternatives, the MYRRHA concept (for the subcritical core, the primary coolant system, the accommodation of experimental rigs, the reactor vessel and the spallation target) has been kept with some modifications to achieve the XT-ADS objectives. The most recent version of the XT-ADS design was presented in the 2007 TWG meeting

  7. Entanglement entropy for free scalar fields in AdS

    CERN Document Server

    Sugishita, Sotaro

    2016-01-01

    We compute entanglement entropy for free massive scalar fields in anti-de Sitter (AdS) space. The entangling surface is a minimal surface whose boundary is a sphere at the boundary of AdS. The entropy can be evaluated from the thermal free energy of the fields on a topological black hole by using the replica method. In odd-dimensional AdS, exact expressions of the Renyi entropy S_n are obtained for arbitrary n. We also evaluate 1-loop corrections coming from the scalar fields to holographic entanglement entropy. Applying the results, we compute the leading difference of entanglement entropy between two holographic CFTs related by a renormalization group flow triggered by a double trace deformation. The difference is proportional to the shift of a central charge under the flow.

  8. Preclinical pharmacology and toxicology study of Ad-hTERT-E1a-Apoptin, a novel dual cancer-specific oncolytic adenovirus

    International Nuclear Information System (INIS)

    Clinical studies have demonstrated that conditionally replicating adenovirus is safe. We constructed an oncolytic adenovirus, Ad-hTERT-E1a-Apoptin, using a cancer-specific promoter (human telomerase reverse transcriptase promoter, hTERTp) and a cancer cell-selective apoptosis-inducing gene (Apoptin). Ad-hTERT-E1a-Apoptin was proven effective both in vitro and in vivo in our previous study. In this study, the preclinical safety profiles of Ad-hTERT-E1a-Apoptin in animal models were investigated. At doses of 5.0 × 108, 2.5 × 109, and 1.25 × 1010 viral particles (VP)/kg, Ad-hTERT-E1a-Apoptin had no adverse effects on mouse behavior, muscle cooperation, sedative effect, digestive system, and nervous systems, or on beagle cardiovascular and respiratory systems at 5.0 × 108, 2.5 × 109, and 1.25 × 1010 VP/kg doses. In acute toxicity tests in mice, the maximum tolerated dose > 5 × 1010 VP/kg. There was no inflammation or ulceration at the injection sites within two weeks. In repeat-dose toxicological studies, the no observable adverse effect levels of Ad-hTERT-E1a-Apoptin in rats (1.25 × 1010 VP/kg) and beagles (2.5 × 109 VP/kg) were 62.5- and 12.5-fold of the proposed clinical dose, respectively. The anti-virus antibody was produced in animal sera. Bone marrow examination revealed no histopathological changes. Guinea pigs sensitized by three repeated intraperitoneal injections of 1.35 × 1010 VP/mL Ad-hTERT-E1a-Apoptin each and challenged by one intravenous injection of 1.67 × 108 VP/kg Ad-hTERT-E1a-Apoptin did not exhibit any sign of systemic anaphylaxis. Our data from different animal models suggest that Ad-hTERT-E1a-Apoptin is a safe anti-tumor therapeutic agent. - Highlights: • We use the rodents and non-rodents animal models to evaluation Ad-hTERT-E1a-Apoptin. • Ad-hTERT-E1a-Apoptin is a safe anti-tumor therapeutic agent. • Demonstrate the safety and feasibility dose of injected Ad-hTERT-E1a-Apoptin

  9. Preclinical pharmacology and toxicology study of Ad-hTERT-E1a-Apoptin, a novel dual cancer-specific oncolytic adenovirus

    Energy Technology Data Exchange (ETDEWEB)

    Qi, Yanxin [State Key Laboratory of Polymer Physics and Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022 (China); Institute of Military Veterinary, Academy of Military Medical Sciences of PLA, Changchun 130122 (China); Guo, Huanhuan [Institute of Military Veterinary, Academy of Military Medical Sciences of PLA, Changchun 130122 (China); Changchun Brother Biotech Co., Ltd., Changchun, 130000 (China); Hu, Ningning; He, Dongyun [Institute of Military Veterinary, Academy of Military Medical Sciences of PLA, Changchun 130122 (China); The Key Laboratory of Jilin Province for Zoonosis Prevention and Control, Changchun 130122 (China); Zhang, Shi [Institute of Military Veterinary, Academy of Military Medical Sciences of PLA, Changchun 130122 (China); School of Clinical Medicine, Jilin University, Changchun 130001 (China); Chu, Yunjie [Affiliated Hospital of Changchun University of Traditional Chinese Medicine, Changchun 130021 (China); Huang, Yubin [State Key Laboratory of Polymer Physics and Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022 (China); Li, Xiao, E-mail: lixiao06@mails.jlu.edu.cn [Institute of Military Veterinary, Academy of Military Medical Sciences of PLA, Changchun 130122 (China); The Key Laboratory of Jilin Province for Zoonosis Prevention and Control, Changchun 130122 (China); Sun, LiLi, E-mail: linjiaxiaoya@163.com [Department of Head and Neck Surgery, Tumor Hospital of Jilin Province, Changchun 130012 (China); Jin, Ningyi, E-mail: ningyij@126.com [Institute of Military Veterinary, Academy of Military Medical Sciences of PLA, Changchun 130122 (China); The Key Laboratory of Jilin Province for Zoonosis Prevention and Control, Changchun 130122 (China)

    2014-10-15

    Clinical studies have demonstrated that conditionally replicating adenovirus is safe. We constructed an oncolytic adenovirus, Ad-hTERT-E1a-Apoptin, using a cancer-specific promoter (human telomerase reverse transcriptase promoter, hTERTp) and a cancer cell-selective apoptosis-inducing gene (Apoptin). Ad-hTERT-E1a-Apoptin was proven effective both in vitro and in vivo in our previous study. In this study, the preclinical safety profiles of Ad-hTERT-E1a-Apoptin in animal models were investigated. At doses of 5.0 × 10{sup 8}, 2.5 × 10{sup 9}, and 1.25 × 10{sup 10} viral particles (VP)/kg, Ad-hTERT-E1a-Apoptin had no adverse effects on mouse behavior, muscle cooperation, sedative effect, digestive system, and nervous systems, or on beagle cardiovascular and respiratory systems at 5.0 × 10{sup 8}, 2.5 × 10{sup 9}, and 1.25 × 10{sup 10} VP/kg doses. In acute toxicity tests in mice, the maximum tolerated dose > 5 × 10{sup 10} VP/kg. There was no inflammation or ulceration at the injection sites within two weeks. In repeat-dose toxicological studies, the no observable adverse effect levels of Ad-hTERT-E1a-Apoptin in rats (1.25 × 10{sup 10} VP/kg) and beagles (2.5 × 10{sup 9} VP/kg) were 62.5- and 12.5-fold of the proposed clinical dose, respectively. The anti-virus antibody was produced in animal sera. Bone marrow examination revealed no histopathological changes. Guinea pigs sensitized by three repeated intraperitoneal injections of 1.35 × 10{sup 10} VP/mL Ad-hTERT-E1a-Apoptin each and challenged by one intravenous injection of 1.67 × 10{sup 8} VP/kg Ad-hTERT-E1a-Apoptin did not exhibit any sign of systemic anaphylaxis. Our data from different animal models suggest that Ad-hTERT-E1a-Apoptin is a safe anti-tumor therapeutic agent. - Highlights: • We use the rodents and non-rodents animal models to evaluation Ad-hTERT-E1a-Apoptin. • Ad-hTERT-E1a-Apoptin is a safe anti-tumor therapeutic agent. • Demonstrate the safety and feasibility dose of injected Ad

  10. Sources of ground movement at Vesuvius before the AD 79 eruption: Evidence from contemporary accounts and archaeological studies

    Science.gov (United States)

    Marturano, Aldo

    2008-11-01

    Historical sources have recorded earthquake shocks, their effects and difficulties that local inhabitants experienced before the AD 79 Pompeii eruption. Archaeological studies pointed out the effects of such seismicity, and have also evidenced that several water crises were occurring at Pompeii in that period. Indeed numerous sources show that, at the time of eruption, and probably some time before, the civic aqueduct, having ceased to be supplied by the regional one, was out of order and that a new one was being built. Since Roman aqueducts were usually built with a recommended minimum mean slope of 20 cm/km and Pompeii's aqueduct sloped from the nearby Apennines toward the town, this slope could have been easily cancelled by uplift that occurred in the area even if this was only moderate. For the crustal deformations a volcanic origin is proposed and a point source model is used to explain the observations. Simple analysis of the available data suggests that the ground deformations were caused by a < 2 km 3 volumetric change at a depth of ˜ 8 km that happened over the course of several decades.

  11. Performance-Related Pay: A Case Study.

    Science.gov (United States)

    Swabe, A. I. R.

    1989-01-01

    Discusses performance-related pay and why the system was introduced, how it was negotiated, and how it has operated. The case study illustrated is in a British financial services company where the system was negotiated in 1986 and began in 1987. (JOW)

  12. Mixed-symmetry fields in AdS(5), conformal fields, and AdS/CFT

    CERN Document Server

    Metsaev, R R

    2014-01-01

    Mixed-symmetry arbitrary spin massive, massless, and self-dual massive fields in AdS(5) are studied. Light-cone gauge actions for such fields leading to decoupled equations of motion are constructed. Light-cone gauge formulation of mixed-symmetry anomalous conformal currents and shadows in 4d flat space is also developed. AdS/CFT correspondence for normalizable and non-normalizable modes of mixed-symmetry AdS fields and the respective boundary mixed-symmetry anomalous conformal currents and shadows is studied. We demonstrate that the light-cone gauge action for massive mixed-symmetry AdS field evaluated on solution of the Dirichlet problem amounts to the light-cone gauge 2-point vertex of mixed-symmetry anomalous shadow. Also we show that UV divergence of the action for mixed-symmetry massive AdS field with some particular value of mass parameter evaluated on the Dirichlet problem amounts to the action of long mixed-symmetry conformal field, while UV divergence of the action for mixed-symmetry massless AdS fi...

  13. Generalized thermodynamic identity and new Maxwell's law for charged AdS black hole

    CERN Document Server

    Zhao, Zixu

    2016-01-01

    We study the thermodynamic properties of the RN-AdS black hole in full phase space and propose a generalized thermodynamic identity. As an example, we use it to find relations of thermodynamical coefficients between the grand canonical and canonical ensembles. We also show, for the first order phase transition, that the usual Maxwell's equal area law should be extended to a new form for the RN-AdS black hole.

  14. A combined study for turning CO$_2$ and H$_2$O into value-added products in a dielectric barrier discharge

    CERN Document Server

    Snoeckx, Ramses; Aerts, Robby; Dufour, Thierry; Reniers, François; Bogaerts, Annemie

    2016-01-01

    A combination of experiments and extensive modelling, including a chemical kinetics analysis, was performed for a CO$_2$/H$_2$O plasma in a dielectric barrier discharge. This provides a better understanding of the mechanisms related to the reactivity of the plasma and of the conversions into value-added products, such as methanol.

  15. Logarithmic conformal field theories and AdS correspondence

    OpenAIRE

    Khorrami, A. M. Ghezelbash. M.; Aghamohammadi, A

    1998-01-01

    We generalize the Maldacena correspondence to the logarithmic conformal field theories. We study the correspondence between field theories in (d+1)-dimensional AdS space and the d-dimensional logarithmic conformal field theories in the boundary of $AdS_{d+1}$. Using this correspondence, we get the n-point functions of the corresponding logarithmic conformal field theory in d-dimensions.

  16. Experimental study of relative, turbulent diffusion

    DEFF Research Database (Denmark)

    Mann, J.; Ott, Søren; Andersen, J.S.

    1999-01-01

    The purpose is to study relative turbulent diffusion under controlled, reproducible conditions in the laboratory in order to estimate the constant C in Richardson-Obukhov's law. We get C #approx# 0.4 -- 0.6. We furthermore measure the distance-neighbourfunction, which is the probability density...... system with two computers each equipped with a frame grabber card. In the search for the best experimentalmethods we have revised the concept of local homogeneity and derived a law for the velocity--acceleration structure function. A second by-product of this effort is a relatively simple derivation...

  17. Effect of dexamethasone added to lidocaine in supraclavicular brachial plexus block: A prospective, randomised, double-blind study

    Directory of Open Access Journals (Sweden)

    Prashant A Biradar

    2013-01-01

    Full Text Available Background: Different additives have been used to prolong brachial plexus block. We performed a prospective, randomised, double-blind study to evaluate the effect of dexamethasone added to lidocaine on the onset and duration of supraclavicular brachial plexus block as this is the most common type of brachial block performed in our institute. Methods: Sixty American Society of Anaesthesiologist′s physical status I and II patients undergoing elective hand, forearm and elbow surgery under brachial plexus block were randomly allocated to receive either 1.5% lidocaine (7 mg/kg with adrenaline (1:200,000 and 2 ml of normal saline (group C, n=30 or 1.5% lidocaine (7 mg/kg with adrenaline (1:200,000 and 2 ml of dexamethasone (8 mg (group D, n=30. The block was performed using a nerve stimulator. Onset and duration of sensory and motor blockade were assessed. The sensory and motor blockade of radial, median, ulnar and musculocutaneous nerves were evaluated and recorded at 5, 10, 20, 120 min, and at every 30 min thereafter. Results: Two patients were excluded from the study because of block failure. The onset of sensory and motor blockade (13.4±2.8 vs. 16.0±2.3 min and 16.0±2.7 vs. 18.7±2.8 min, respectively were significantly more rapid in the dexamethasone group than in the control group ( P=0.001. The duration of sensory and motor blockade (326±58.6 vs. 159±20.1 and 290.6±52.7 vs. 135.5±20.3 min, respectively were significantly longer in the dexamethasone group than in the control group ( P=0.001. Conclusion: Addition of dexamethasone to 1.5% lidocaine with adrenaline in supraclavicular brachial plexus block speeds the onset and prolongs the duration of sensory and motor blockade.

  18. An Empirical Comparative Study of Checklist based and Ad Hoc Code Reading Techniques in a Distributed Groupware Environment

    CERN Document Server

    Akinola, Olalekan S

    2009-01-01

    Software inspection is a necessary and important tool for software quality assurance. Since it was introduced by Fagan at IBM in 1976, arguments exist as to which method should be adopted to carry out the exercise, whether it should be paper based or tool based, and what reading technique should be used on the inspection document. Extensive works have been done to determine the effectiveness of reviewers in paper based environment when using ad hoc and checklist reading techniques. In this work, we take the software inspection research further by examining whether there is going to be any significant difference in defect detection effectiveness of reviewers when they use either ad hoc or checklist reading techniques in a distributed groupware environment. Twenty final year undergraduate students of computer science, divided into ad hoc and checklist reviewers groups of ten members each were employed to inspect a medium sized java code synchronously on groupware deployed on the Internet. The data obtained were...

  19. Analytical study of the frequency shifts of micro and nano clamped–clamped beam resonators due to an added mass

    KAUST Repository

    Bouchaala, Adam M.

    2016-03-18

    We present analytical formulations to calculate the induced resonance frequency shifts of electrically actuated clamped–clamped micro and nano (Carbon nanotube) beams due to an added mass. Based on the Euler–Bernoulli beam theory, we investigate the linear dynamic responses of the beams added masses, which are modeled as discrete point masses. Analytical expressions based on perturbation techniques and a one-mode Galerkin approximation are developed to calculate accurately the frequency shifts under a DC voltage as a function of the added mass and position. The analytical results are compared to numerical solution of the eigenvalue problem. Results are shown for the fundamental as well as the higher-order modes of the beams. The results indicate a significant increase in the frequency shift, and hence the sensitivity of detection, when scaling down to nano scale and using higher-order modes. © 2016 Springer Science+Business Media Dordrecht

  20. The impact of net value added on predicting the earnings and operating cash flow: An empirical study based on Tehran Stock Exchange

    Directory of Open Access Journals (Sweden)

    Omid Imani Khoshkhoo

    2013-12-01

    Full Text Available Information content of earnings and its components and other issues except the earnings such as the operating cash flow (OCF have been tested widely in the accounting and finance literature. Since they have had an essential role in most cases including financial reporting, contracts and evaluation models, specifying the items and financial variables that have had a significant relationship with these two variables are expected to be of utmost importance. One example of these variables and indicators is the value added. Although this variable has an economic concept, reporting of value added to the beneficiaries of business entity as the value-added statement has been observed in the field of accounting theories for many years. The main objective of this study was to investigate the effect of net value added (NVA as the basic result of value-added statement in predicting the accounting earnings and operating cash flow. For this purpose, the relationship of changes in net value added with the changes in accounting earnings and operating cash flow of listed companies in Tehran Stock Exchange from 2007 to 2011 was tested. Firstly the Single variable cross-sectional regression was analyzed and then the panel data analysis with the PLS technique was used to do a pooled analysis. The results of testing research hypothesis imply the significant relationship between changes in net value added and accounting earnings in the listed companies as cross-sectional and pooled forms. The results showed no significant relationship between changes in net value added and operating cash flow in the listed companies neither in cross-sectional nor pooled form.

  1. Value-Added Results for Public Virtual Schools in California

    Science.gov (United States)

    Ford, Richard; Rice, Kerry

    2015-01-01

    The objective of this paper is to present value-added calculation methods that were applied to determine whether online schools performed at the same or different levels relative to standardized testing. This study includes information on how we approached our value added model development and the results for 32 online public high schools in…

  2. Study of the pyrolysis of sludge and sludge/disposal filter cake mix for the production of value added products

    OpenAIRE

    VELGHE, Inge; Carleer, Robert; Yperman, Jan; Schreurs, Sonja

    2013-01-01

    Slow and fast pyrolysis of sludge and sludge/disposal filter cake (FC) mix are performed to investigate the liquid and solid products for their use as value added products. The obtained slow pyrolysis liquid products separate in an oil, a water rich fraction and a valuable crystalline solid 5,5-dimethyl hydantoin. During fast pyrolysis, mainly an oil fraction is formed. Aliphatic acids and amides present in the water rich fractions can be considered as value added products and could be purifi...

  3. Asymptotically AdS spacetimes with a timelike Kasner singularity

    Science.gov (United States)

    Ren, Jie

    2016-07-01

    Exact solutions to Einstein's equations for holographic models are presented and studied. The IR geometry has a timelike cousin of the Kasner singularity, which is the less generic case of the BKL (Belinski-Khalatnikov-Lifshitz) singularity, and the UV is asymptotically AdS. This solution describes a holographic RG flow between them. The solution's appearance is an interpolation between the planar AdS black hole and the AdS soliton. The causality constraint is always satisfied. The entanglement entropy and Wilson loops are discussed. The boundary condition for the current-current correlation function and the Laplacian in the IR is examined. There is no infalling wave in the IR, but instead, there is a normalizable solution in the IR. In a special case, a hyperscaling-violating geometry is obtained after a dimensional reduction.

  4. Towards integrability for AdS3/CFT2

    International Nuclear Information System (INIS)

    We review the recent progress towards applying worldsheet integrability techniques to the AdS3/CFT2 correspondence to find its all-loop S matrix and Bethe–Yang equations. We study in full detail the massive sector of AdS3×S3×T4 superstrings supported by pure Ramond–Ramond (RR) fluxes. The extension of this machinery to accommodate massless modes, to the AdS3×S3×S3×S1 pure-RR background and to backgrounds supported by mixed background fluxes is also reviewed. While the results discussed here were found elsewhere, our presentation sometimes deviates from the one found in the original literature in an effort to be pedagogical and self-contained. (topical review)

  5. Geospatial modeling approach to monument construction using Michigan from A.D. 1000-1600 as a case study.

    Science.gov (United States)

    Howey, Meghan C L; Palace, Michael W; McMichael, Crystal H

    2016-07-01

    Building monuments was one way that past societies reconfigured their landscapes in response to shifting social and ecological factors. Understanding the connections between those factors and monument construction is critical, especially when multiple types of monuments were constructed across the same landscape. Geospatial technologies enable past cultural activities and environmental variables to be examined together at large scales. Many geospatial modeling approaches, however, are not designed for presence-only (occurrence) data, which can be limiting given that many archaeological site records are presence only. We use maximum entropy modeling (MaxEnt), which works with presence-only data, to predict the distribution of monuments across large landscapes, and we analyze MaxEnt output to quantify the contributions of spatioenvironmental variables to predicted distributions. We apply our approach to co-occurring Late Precontact (ca. A.D. 1000-1600) monuments in Michigan: (i) mounds and (ii) earthwork enclosures. Many of these features have been destroyed by modern development, and therefore, we conducted archival research to develop our monument occurrence database. We modeled each monument type separately using the same input variables. Analyzing variable contribution to MaxEnt output, we show that mound and enclosure landscape suitability was driven by contrasting variables. Proximity to inland lakes was key to mound placement, and proximity to rivers was key to sacred enclosures. This juxtaposition suggests that mounds met local needs for resource procurement success, whereas enclosures filled broader regional needs for intergroup exchange and shared ritual. Our study shows how MaxEnt can be used to develop sophisticated models of past cultural processes, including monument building, with imperfect, limited, presence-only data.

  6. Ad libitum fluid intake leads to no leg swelling in male Ironman triathletes – an observational field study

    Directory of Open Access Journals (Sweden)

    Meyer Michael

    2012-09-01

    Full Text Available Abstract Background An association between fluid intake and limb swelling has been described for 100-km ultra-marathoners. We investigated a potential development of peripheral oedemata in Ironman triathletes competing over 3.8 km swimming, 180 km cycling and 42.2 km running. Methods In 15 male Ironman triathletes, fluid intake, changes in body mass, fat mass, skeletal muscle mass, limb volumes and skinfold thickness were measured. Changes in renal function, parameters of skeletal muscle damage, hematologic parameters and osmolality in both serum and urine were determined. Skinfold thicknesses at hands and feet were measured using LIPOMETER® and changes of limb volumes were measured using plethysmography. Results The athletes consumed a total of 8.6 ± 4.4 L of fluids, equal to 0.79 ± 0.43 L/h. Body mass, skeletal muscle mass and the volume of the lower leg decreased (p p >0.05. The decrease in skeletal muscle mass was associated with the decrease in body mass (p p >0.05. Haemoglobin, haematocrit and serum sodium remained unchanged (p >0.05. Osmolality in serum and urine increased (p +] (r = −0.52, p r = −0.60, p Conclusions In these Ironman triathletes, ad libitum fluid intake maintained plasma [Na+] and plasma osmolality and led to no peripheral oedemata. The volume of the lower leg decreased and the decrease was unrelated to fluid intake. Future studies may investigate ultra-triathletes competing in a Triple Iron triathlon over 11.4 km swimming, 540 km cycling and 126.6 km running to find an association between fluid intake and the development of peripheral oedemata.

  7. Geospatial modeling approach to monument construction using Michigan from A.D. 1000-1600 as a case study.

    Science.gov (United States)

    Howey, Meghan C L; Palace, Michael W; McMichael, Crystal H

    2016-07-01

    Building monuments was one way that past societies reconfigured their landscapes in response to shifting social and ecological factors. Understanding the connections between those factors and monument construction is critical, especially when multiple types of monuments were constructed across the same landscape. Geospatial technologies enable past cultural activities and environmental variables to be examined together at large scales. Many geospatial modeling approaches, however, are not designed for presence-only (occurrence) data, which can be limiting given that many archaeological site records are presence only. We use maximum entropy modeling (MaxEnt), which works with presence-only data, to predict the distribution of monuments across large landscapes, and we analyze MaxEnt output to quantify the contributions of spatioenvironmental variables to predicted distributions. We apply our approach to co-occurring Late Precontact (ca. A.D. 1000-1600) monuments in Michigan: (i) mounds and (ii) earthwork enclosures. Many of these features have been destroyed by modern development, and therefore, we conducted archival research to develop our monument occurrence database. We modeled each monument type separately using the same input variables. Analyzing variable contribution to MaxEnt output, we show that mound and enclosure landscape suitability was driven by contrasting variables. Proximity to inland lakes was key to mound placement, and proximity to rivers was key to sacred enclosures. This juxtaposition suggests that mounds met local needs for resource procurement success, whereas enclosures filled broader regional needs for intergroup exchange and shared ritual. Our study shows how MaxEnt can be used to develop sophisticated models of past cultural processes, including monument building, with imperfect, limited, presence-only data. PMID:27330115

  8. Phases of Global AdS Black Holes

    CERN Document Server

    Basu, Pallab; Subramanian, P N Bala

    2016-01-01

    We study the phases of gravity coupled to a charged scalar and gauge field in an asymptotically Anti-de Sitter spacetime ($AdS_4$) in the grand canonical ensemble. For the conformally coupled scalar, an intricate phase diagram is charted out between the four relevant solutions: global AdS, boson star, Reissner-Nordstrom black hole and the hairy black hole. The nature of the phase diagram undergoes qualitative changes as the charge of the scalar is changed, which we discuss. We also discuss the new features that arise in the extremal limit.

  9. Phases of global AdS black holes

    Science.gov (United States)

    Basu, Pallab; Krishnan, Chethan; Subramanian, P. N. Bala

    2016-06-01

    We study the phases of gravity coupled to a charged scalar and gauge field in an asymptotically Anti-de Sitter spacetime ( AdS 4) in the grand canonical ensemble. For the conformally coupled scalar, an intricate phase diagram is charted out between the four relevant solutions: global AdS, boson star, Reissner-Nordstrom black hole and the hairy black hole. The nature of the phase diagram undergoes qualitative changes as the charge of the scalar is changed, which we discuss. We also discuss the new features that arise in the extremal limit.

  10. A study of epilepsy-related psychosis

    OpenAIRE

    Roy A; Rajesh S; Iby N; Jose J; Sarma G

    2003-01-01

    The association of epilepsy and psychosis is studied. Among the 500 patients of epilepsy evaluated, there were 12 patients, 8 males and 4 females with epilepsy-related psychosis. Their average age was 38 years. The interval between the age of onset of epilepsy and psychotic features was 9 years. Complex partial seizures were present in 7 patients and primary generalized tonic-clonic seizure was present in 1 patient. Four patients had post-ictal psychosis, 7 had acute interictal psychosis and ...

  11. Ad Hoc网络%Ad Hoc Network

    Institute of Scientific and Technical Information of China (English)

    王海涛

    2005-01-01

    首先介绍了Ad Hoc网络的基本概念、技术特点以及关键技术等,然后较为全面地归纳了Ad Hoc网络的典型应用,最后讨论了Ad Hoc网络的发展趋势和有待解决的问题.

  12. Słownictwo z dziedziny mediów, reklamy i public relations jako przykład języka zawodowego.

    OpenAIRE

    Nerwiński, Wojciech

    2007-01-01

    In my thesis “Vocabulary from media, advertising and public relations as an example of professional language”. I have analysed vocabulary which concerns media, advertising and public relations in Poland. These three questions are very young in Poland’s language and home market. First of all I show in my thesis the research and development of the professional language in Poland. Afterwards I study the word's lexical in my work, as a criterion taken to the Polish language. English words that ha...

  13. Integrated Study of AD-Net Mie-Lidar Network and Data Assimilated CTM for Asian Dust Epidemiology in Japan

    Science.gov (United States)

    Shimizu, Atsushi; Nishizawa, Tomoaki; Sugimoto, Nobuo; Matsui, Ichiro; Kobayashi, Hiroshi; Maki, Takashi; Sekiyama, Thomas T.; Kanatani, Kumiko

    2016-06-01

    Mie-scattering lidar data are going to be incorporated into data assimilation in chemical transport model to represent more reliable / useful horizontal distribution of Asian dust over Japan. The result is utilized in an epidemiology which surveys effect of Asian dust to human health. Wider application of AD-Net is expected in the field of environmental researches.

  14. Combining Q2MM Modeling and Kinetic Studies for Refinement of the Osmium-catalyzed Asymmetric Dihydroxylation (AD) Mnemonic

    DEFF Research Database (Denmark)

    Fristrup, Peter; Jensen, Gitte Holm; Andersen, Marie Louise Nygaard;

    2006-01-01

    The interactions between the substrate and the ligand in the Sharpless AD reaction have been examined in detail, using a combination of substrate competition experiments and molecular modeling of transition states. There is a good agreement between computational and experimental results, in parti...

  15. Entanglement temperature and perturbed AdS3 geometry

    Science.gov (United States)

    Levine, G. C.; Caravan, B.

    2016-06-01

    Generalizing the first law of thermodynamics, the increase in entropy density δ S (x ) of a conformal field theory (CFT) is proportional to the increase in energy density, δ E (x ) , of a subsystem divided by a spatially dependent entanglement temperature, TE(x ) , a fixed parameter determined by the geometry of the subsystem, crossing over to thermodynamic temperature at high temperatures. In this paper we derive a generalization of the thermodynamic Clausius relation, showing that deformations of the CFT by marginal operators are associated with spatial temperature variations, δ TE(x ) , and spatial energy correlations play the role of specific heat. Using AdS/CFT duality we develop a relationship between a perturbation in the local entanglement temperature of the CFT and the perturbation of the bulk AdS metric. In two dimensions, we demonstrate a method through which direct diagonalizations of the boundary quantum theory may be used to construct geometric perturbations of AdS3 .

  16. Scattering States in AdS/CFT

    Energy Technology Data Exchange (ETDEWEB)

    Fitzpatrick, A.Liam; /Boston U.; Kaplan, Jared; /SLAC

    2012-02-14

    We show that suitably regulated multi-trace primary states in large N CFTs behave like 'in' and 'out' scattering states in the flat-space limit of AdS. Their transition matrix elements approach the exact scattering amplitudes for the bulk theory, providing a natural CFT definition of the flat space S-Matrix. We study corrections resulting from the AdS curvature and particle propagation far from the center of AdS, and show that AdS simply provides an IR regulator that disappears in the flat space limit.

  17. Study of the IDS in wireless Ad Hoc networks based on mobile agents%基于移动代理的无线Ad Hoc网络IDS研究

    Institute of Scientific and Technical Information of China (English)

    张念丽

    2006-01-01

    介绍了无线Ad Hoc网络的特点和面临的安全问题,分析了移动代理在Ad Hoc网络入侵检测系统中的适用性,给出了一种基于移动代理的无线Ad Hoc网络入侵检测系统模型.

  18. Eternal Black Holes in AdS

    OpenAIRE

    Maldacena, Juan M.

    2001-01-01

    We propose a dual non-perturbative description for maximally extended Schwarzschild Anti-de-Sitter spacetimes. The description involves two copies of the conformal field theory associated to the AdS spacetime and an initial entangled state. In this context we also discuss a version of the information loss paradox and its resolution.

  19. Current status of AdS instability

    CERN Document Server

    CERN. Geneva

    2016-01-01

    arXiv:1403.6471 and thoroughly developed in arXiv:1407.6273. On the other hand the negative cosmological constant allows for the existence of stable, time-periodic, asymptotically AdS solutions of Einstein equations [arXiv:1303.3186].

  20. AdS braneworld with Backreaction

    CERN Document Server

    Bilic, Neven

    2014-01-01

    We review the tachyon model derived from the dynamics of a 3-brane moving in the AdS5 bulk. The bulk geometry is based on the Randall-Sundrum II model extended to include the radion. The effective tachyon Lagrangian is modified due to the back-reaction of the brane on the bulk geometry.

  1. Intrusion detection in wireless ad-hoc networks

    CERN Document Server

    Chaki, Nabendu

    2014-01-01

    Presenting cutting-edge research, Intrusion Detection in Wireless Ad-Hoc Networks explores the security aspects of the basic categories of wireless ad-hoc networks and related application areas. Focusing on intrusion detection systems (IDSs), it explains how to establish security solutions for the range of wireless networks, including mobile ad-hoc networks, hybrid wireless networks, and sensor networks.This edited volume reviews and analyzes state-of-the-art IDSs for various wireless ad-hoc networks. It includes case studies on honesty-based intrusion detection systems, cluster oriented-based

  2. The HOMA-Adiponectin (HOMA-AD) Closely Mirrors the HOMA-IR Index in the Screening of Insulin Resistance in the Brazilian Metabolic Syndrome Study (BRAMS)

    Science.gov (United States)

    Cassani, Roberta Soares Lara; Forti, Adriana Costa e; Pareja, José Carlos; Tambascia, Marcos Antonio; Geloneze, Bruno

    2016-01-01

    Background The major adverse consequences of obesity are associated with the development of insulin resistance (IR) and adiposopathy. The Homeostasis Model Assessment-Adiponectin (HOMA-AD) was proposed as a modified version of the HOMA1-IR, which incorporates adiponectin in the denominator of the index. Objectives To evaluate the performance of the HOMA-AD index compared with the HOMA1-IR index as a surrogate marker of IR in women, and to establish the cutoff value of the HOMA-AD. Subjects/Methods The Brazilian Metabolic Syndrome Study (BRAMS) is a cross-sectional multicenter survey. The data from 1,061 subjects met the desired criteria: 18–65 years old, BMI: 18.5–49.9 Kg/m² and without diabetes. The IR was assessed by the indexes HOMA1-IR and HOMA-AD (total sample) and by the hyperglycemic clamp (n = 49). Metabolic syndrome was defined using the IDF criteria. Results For the IR assessed by the clamp, the HOMA-AD demonstrated a stronger coefficient of correlation (r = -0.64) compared with the HOMA1-IR (r = -0.56); p 0.05). The optimal cutoff identified for the HOMA-AD for the diagnosis of IR was 0.95. Conclusions The HOMA-AD index was demonstrated to be a useful surrogate marker for detecting IR among adult women and presented a similar performance compared with the HOMA1-IR index. These results may assist physicians and researchers in determining which method to use to evaluate IR in light of the available facilities. PMID:27490249

  3. [Therapeutic effects of larger doses of arachidonic acid added to DHA on social impairment and its relation to alterations of polyunsaturated fatty acids in individuals with autism spectrum disorders].

    Science.gov (United States)

    Yui, Kunio; Koshiba, Mamiko; Nakamura, Shun; Onishi, Masako

    2011-06-01

    The polyunsaturated fatty acids (PUFAs), arachidonic acid (ARA) and docosahexaenoic acid (DHA) may play key roles in brain network maturation. ARA plays an important role in signal transduction related to neuronal maturation. This study aims to evaluate the efficacy of supplementing with larger doses of ARA added to DHA in a double-blind, placebo-controlled 16-week trial. To confirm findings observed in the placebo-controlled trial, an additional 16-week open-label study was further conducted. To examine the relationship between the efficacy of the supplementation regimen and alterations in PUFAs levels, we examined plasma levels of PUFAs. We used the Social Responsiveness Scale (SRS) and the Aberrant Behavior Checklist-Community (ABC) to estimate psychotic symptoms. Repeated measures ANOVA revealed that this supplementation significantly improved SRS-measured communication as well as ABC-measured social withdrawal during the placebo-controlled trial. The treatment effect sizes were more favorable for the treatment group compared with the placebo group (communication: 0.87 vs. 0.44; social withdrawal: 0.88 vs. 0.54). At the end of the placebo-controlled trial, there was a significant difference in the change in plasma ARA levels from the baseline and a trend towards a significant difference in plasma ARA levels between the two groups. The open-label study was not powered to detect significant improvements in the outcome measures or significant differences in plasma ARA levels. The present clinical trials suggest that supplementation with larger ARA doses added to DHA improves social impairment in individuals with ASD via ARA-induced upregulation of neuronal functioning. PMID:21800702

  4. Analisis Kinerja Keuangan Dengan Menggunakan Rasio-Rasio Keuangan Dan Economic Value Added (Studi Kasus: PT. Bank Syariah Mandiri

    Directory of Open Access Journals (Sweden)

    Endri Piliang

    2008-08-01

    Full Text Available This paper analyzes the financial peformance of Bank Syariah Mandiri (BSM using financial ratios and Economic Value Added (EVA method. The ratio of Net Profit Margin (NPM, Return on Asset (ROA, Return on Equity (ROE, and Capital Adequacy Ratio (CAR show fluctuative result. However, on average, during 2003-2006 financial performance of BSM was increased considerably. While using EVA method, its result during 2003-2006 tend to decreased and even negative. The best performance was happening in 2003, whereby during 2004 - 2006 EVA result was lower than zero meaning that financial performance of BSM do not have any economic contribution to the institution especially for the interest of investor.Keywords: Economic Value Added, NPM, ROA, ROE, CAR

  5. Age-dependent modifications of AMPA receptor subunit expression levels and related cognitive effects in 3xTg-AD mice

    Directory of Open Access Journals (Sweden)

    Pamela eCantanelli

    2014-08-01

    Full Text Available GluA1, GluA2, GluA3, and GluA4 are the constitutive subunits of AMPA receptors (AMPARs, the major mediators of fast excitatory transmission in the mammalian central nervous system. Most AMPARs are Ca2+-impermeable because of the presence of the GluA2 subunit. GluA2 mRNA undergoes an editing process that results in a Q to R substitution, a key factor in the regulation of AMPAR Ca2+-permeability. AMPARs lacking GluA2 or containing the unedited subunit are permeable to Ca2+ and Zn2+. The phenomenon physiologically modulates synaptic plasticity while, in pathologic conditions, leads to increased vulnerability to excitotoxic neuronal death. Given the importance of these subunits, we have therefore evaluated possible associations between changes in expression levels of AMPAR subunits and development of cognitive deficits in 3xTg-AD mice, a widely investigated transgenic mouse model of Alzheimer’s disease. With qRT-PCR, we assayed hippocampal mRNA expression levels of GluA1-4 subunits occurring in young [3 months of age (m.o.a.] and old (12 m.o.a Tg-AD mice and made comparisons with levels found in age-matched wild type (WT mice. Efficiency of GluA2 RNA editing was also analyzed. All animals were cognitively tested for short- and long-term spatial memory with the Morris Water Maze (MWM navigation task. 3xTg-AD mice showed age-dependent decreases of mRNA levels for all the AMPAR subunits, with the exception of GluA2. Editing remained fully efficient with aging in 3xTg-AD and WT mice. A one-to-one correlation analysis between MWM performances and GluA1-4 mRNA expression profiles showed negative correlations between GluA2 levels and MWM performances in young 3xTg-AD mice. On the contrary, positive correlations between GluA2 mRNA and MWM performances were found in young WT mice. Our data suggest that increases of AMPARs that contain GluA1, GluA3, and GluA4 subunits may help in maintaining cognition in pre-symptomatic 3xTg-AD mice.

  6. 关于EVA贴现模型的探讨%Study on discounted economic value added valuation method

    Institute of Scientific and Technical Information of China (English)

    范洪波; 张丽梅

    2004-01-01

    主要介绍了公司价值评估的一种方法--EVA贴现估价法(The Discounted Economic Value Added Valuation Method).与股利贴现模型和自由现金流模型相比EVA贴现估价法的优越性在于获取数据较容易,重视账面值的分析,目前越来越受到关注.

  7. A study of epilepsy-related psychosis

    Directory of Open Access Journals (Sweden)

    Roy A

    2003-07-01

    Full Text Available The association of epilepsy and psychosis is studied. Among the 500 patients of epilepsy evaluated, there were 12 patients, 8 males and 4 females with epilepsy-related psychosis. Their average age was 38 years. The interval between the age of onset of epilepsy and psychotic features was 9 years. Complex partial seizures were present in 7 patients and primary generalized tonic-clonic seizure was present in 1 patient. Four patients had post-ictal psychosis, 7 had acute interictal psychosis and 1 patient had chronic psychosis. The inter-ictal and chronic psychoses were schizophreniform whereas the post-ictal psychoses were not. EEG showed a temporal focus in 7 patients with complex partial seizures and an extra-temporal focus was identified in 4 out of the other 5 patients. Imaging (CT scan/MRI revealed abnormalities in 10 patients. This study attempts to define the characteristics of psychoses occurring in epileptics.

  8. All-loop worldsheet S matrix for AdS_3 x S^3 x T^4

    CERN Document Server

    Borsato, Riccardo; Sfondrini, Alessandro; Stefanski, Bogdan

    2014-01-01

    We obtain the all-loop worldsheet S matrix for fundamental excitations on AdS_3 x S^3 x T^4 by studying the off-shell symmetry algebra of the superspace action in lightcone gauge. The massless modes, unaccounted for in earlier works, are automatically included in our treatment. Their exact dispersion relation is found to be non-relativistic, of giant-magnon form and their scattering is naturally well-defined. This opens the way to a complete investigation of AdS_3/CFT_2 integrability.

  9. Thermodynamic and classical instability of AdS black holes in fourth-order gravity

    International Nuclear Information System (INIS)

    We study thermodynamic and classical instability of AdS black holes in fourth-order gravity. These include the BTZ black hole in new massive gravity, Schwarzschild-AdS black hole, and higher-dimensional AdS black holes in fourth-order gravity. All thermodynamic quantities which are computed using the Abbot-Deser-Tekin method are used to study thermodynamic instability of AdS black holes. On the other hand, we investigate the s-mode Gregory-Laflamme instability of the massive graviton propagating around the AdS black holes. We establish the connection between the thermodynamic instability and the GL instability of AdS black holes in fourth-order gravity. This shows that the Gubser-Mitra conjecture holds for AdS black holes found from fourth-order gravity

  10. Neuroprotective effect of novel cognitive enhancer noopept on AD-related cellular model involves the attenuation of apoptosis and tau hyperphosphorylation

    OpenAIRE

    Ostrovskaya, Rita U; Vakhitova, Yulia V; Kuzmina, Uliyana Sh; Salimgareeva, Milyausha Kh; Zainullina, Liana F; Gudasheva, Tatiana A; Vakhitov, Vener A; Seredenin, Sergey B

    2014-01-01

    Background Noopept (N-phenyl-acetyl-L-prolylglycine ethyl ester) was constructed as a dipeptide analog of the standard cognition enhancer, piracetam. Our previous experiments have demonstrated the cognition restoring effect of noopept in several animal models of Alzheimer disease (AD). Noopept was also shown to prevent ionic disbalance, excitotoxicity, free radicals and pro-inflammatory cytokines accumulation, and neurotrophine deficit typical for different kinds of brain damages, including A...

  11. Vehicular ad hoc network security and privacy

    CERN Document Server

    Lin, X

    2015-01-01

    Unlike any other book in this area, this book provides innovative solutions to security issues, making this book a must read for anyone working with or studying security measures. Vehicular Ad Hoc Network Security and Privacy mainly focuses on security and privacy issues related to vehicular communication systems. It begins with a comprehensive introduction to vehicular ad hoc network and its unique security threats and privacy concerns and then illustrates how to address those challenges in highly dynamic and large size wireless network environments from multiple perspectives. This book is richly illustrated with detailed designs and results for approaching security and privacy threats.

  12. Superradiant instability in AdS

    CERN Document Server

    Ganchev, Bogdan

    2016-01-01

    The phenomenon of superradiance in the context of asymptotically global AdS spacetimes is investigated with particular accent on its effect on the stability of the systems under consideration. To this end, the concept of an asymptotically AdS spacetime is explained, together with its implications on the boundary conditions at $\\mathcal{I}$, as well as the Newman-Penrose-Teukolsky formalism, whereby the Teukolsky master equation in a most general form for Kerr-AdS is given. Furthermore, work done in the cases of RN-AdS and Kerr-AdS is laid out in a concise manner, putting emphasis on the important steps taken in determining the endpoint of the superradiant instability in the two configurations. For the former this turns out to be a black hole with reduced charge and a static charged scalar condensate around it, whereas for the latter two of the more probable outcomes are presented, both of which imply a violation of one of the cosmic censorships.

  13. The added prognostic value of MRI findings for recovery in patients with low back pain in primary care: a 1-year follow-up cohort study

    NARCIS (Netherlands)

    E.I.T. de Schepper (Evelien); B.W. Koes (Bart); E.H.G. Oei (Edwin); S.M. Bierma-Zeinstra (Sita); P.A.J. Luijsterburg (Pim)

    2016-01-01

    textabstractPurpose: Information on the prognostic value of MRI findings in low back pain patients in primary care is lacking. The objective of this study is to investigate the added prognostic value of baseline MRI findings over known prognostic factors for recovery at 12-month follow-up in patient

  14. [Study of physical-mechanic characteristics of prosthetic construction after their adjustment with the use of laser welding and hot metal adding].

    Science.gov (United States)

    Gvetadze, R Sh; Rusanov, F S; Mikhas'kov, S V

    2011-01-01

    Study of physical-mechanic characteristics of connecting joints of beam construction after laser welding and hot metal adding was performed. Increase of microhardness of joints as well as small reduction of bending strength of prosthetic constructions was established. PMID:21983619

  15. Delta Plots in the study of individual differences: New tools reveal response inhibition deficits in AD/HD That are eliminated by methylphenidate treatment

    NARCIS (Netherlands)

    K.R. Ridderinkhof; A. Scheres; J. Oosterlaan; J.A. Sergeant

    2005-01-01

    The authors highlight the utility of distribution-analytical techniques in the study of individual differences and clinical disorders. Cognitive deficits associated with attention-deficit/hyperactivity disorder (AD/HD) were examined by using delta-plot analyses of performance data (reaction time and

  16. Delta Plots in the Study of Individual Differences : New Tools Reveal Response Inhibition Deficits in AD-HD That Are Eliminated by Methylphenidate Treatment

    NARCIS (Netherlands)

    Ridderinkhof, K.R.; Scheres, A.P.J.; Oosterlaan, J.; Sergeant, J.A.

    2005-01-01

    The authors highlight the utility of distribution-analytical techniques in the study of individual differences and clinical disorders. Cognitive deficits associated with attention-deficit/hyperactivity disorder (AD/HD) were examined by using delta-plot analyses of performance data (reaction time and

  17. The effect of adding group-based counselling to individual lifestyle counselling on changes in dietary intake. The Inter99 study--a randomized controlled trial

    DEFF Research Database (Denmark)

    Toft, Ulla; Kristoffersen, Lis; Ladelund, Steen;

    2008-01-01

    Few studies have investigated the specific effect of single intervention components in randomized controlled trials. The purpose was to investigate the effect of adding group-based diet and exercise counselling to individual life-style counselling on long-term changes in dietary habits....

  18. 无线传感器网络与传统Ad Hoc网络的比较研究%Comparison study of wireless sensor networks and traditional Ad Hoc networks

    Institute of Scientific and Technical Information of China (English)

    付军; 戴志诚; 汪秉文

    2007-01-01

    近年来,无线通信和电子技术的进步促进了Ad Hoc网络的发展,无线传感器网络是Ad Hoc网络的几大应用领域之一,但与传统Ad Hoc网络比有差异,传统Ad Hoc网络的协议大部分都不适合于无线传感器网络,文中从体系结构、协议栈和应用方面对无线传感器网络和传统Ad Hoc网络进行比较和分析.

  19. Euclidean Wilson loops and minimal area surfaces in lorentzian AdS 3

    Science.gov (United States)

    Irrgang, Andrew; Kruczenski, Martin

    2015-12-01

    The AdS/CFT correspondence relates Wilson loops in N=4 SYM theory to minimal area surfaces in AdS 5 × S 5 space. If the Wilson loop is Euclidean and confined to a plane ( t, x) then the dual surface is Euclidean and lives in Lorentzian AdS 3 ⊂ AdS 5. In this paper we study such minimal area surfaces generalizing previous results obtained in the Euclidean case. Since the surfaces we consider have the topology of a disk, the holonomy of the flat current vanishes which is equivalent to the condition that a certain boundary Schrödinger equation has all its solutions anti-periodic. If the potential for that Schrödinger equation is found then reconstructing the surface and finding the area become simpler. In particular we write a formula for the Area in terms of the Schwarzian derivative of the contour. Finally an infinite parameter family of analytical solutions using Riemann Theta functions is described. In this case, both the area and the shape of the surface are given analytically and used to check the previous results.

  20. 对增值税转型后固定资产涉税事项处理的分析%Dealing with Tax-related Matters of Fixed Assets after Transformation of Value-added Tax

    Institute of Scientific and Technical Information of China (English)

    李玉晗

    2011-01-01

    This paper taks the the transformation reform of value-added tax implemented by State Council from 1st.January, 2009 as the background to analyze the treatment of tax-related matters of fixed assets after the transformation of value-added tax.%本文以国务院于2009年1月1日起实施的增值税转型改革为背景,对增值税转型后固定资产典型涉税事项的处理进行分析.

  1. The effect of adding group-based counselling to individual lifestyle counselling on changes in dietary intake. The Inter99 study – a randomized controlled trial

    OpenAIRE

    Smith Lisa; Pisinger Charlotta; Lau Cathrine; Ovesen Lars; Ladelund Steen; Kristoffersen Lis; Toft Ulla; Borch-Johnsen Knut; Jørgensen Torben

    2008-01-01

    Abstract Background Few studies have investigated the specific effect of single intervention components in randomized controlled trials. The purpose was to investigate the effect of adding group-based diet and exercise counselling to individual life-style counselling on long-term changes in dietary habits. Methods The study was a randomized controlled intervention study. From a general Danish population, aged 30 to 60 years (n = 61,301), two random sample were drawn (group A, n = 11,708; grou...

  2. Instability corners in AdS space

    CERN Document Server

    Dimitrakopoulos, Fotios V; Lippert, Matthew; Yang, I-Sheng

    2014-01-01

    We investigate whether arbitrarily small perturbations in global AdS space are generically unstable and collapse into black holes on the time scale set by gravitational interactions. We argue that current evidence, combined with our analysis, strongly suggests that a set of nonzero measure in the space of initial conditions does not collapse on this time scale. On the other hand, existing results do not provide an equally strong indication whether the unstable solutions also form a set of nonzero measure. We perform an analysis in position space to address this puzzle, and our formalism allows us to directly address the vanishing-amplitude limit. We show that gravitational self-interaction leads to tidal deformations which are equally likely to focus or defocus energy, and we sketch the phase diagram accordingly. We also clarify the connection between gravitational evolution in global AdS and holographic thermalization.

  3. A Simulation Study of a Location Service for Position-Based Routing in Mobile Ad Hoc Networks

    OpenAIRE

    Käsemann, Michael; Hartenstein, Hannes; Füßler, Holger; Mauve, Martin

    2002-01-01

    Position-based routing in a mobile ad hoc network requires geographic addresses. Thus, a node that wants to send a packet to some target node has to know the target's (approximate) current position. In order to provide each node's position to the other network nodes, a distributed location service has to be used. J. Li et al. recently put forward a promising approach called the Grid Location Service' (GLS). In this paper we provide some analyses and evaluations of GLS by means of simulation w...

  4. AD 病程中海马代谢水平与体积改变的研究%The study of hippocampal metabolites level and volumetric changes in AD

    Institute of Scientific and Technical Information of China (English)

    武文博; 刘任远; 张鑫; 朱斌; 张冰; 徐运

    2015-01-01

    hippocampus in Alzheimer disease (AD),mild cognitive impairment(MCI) and normal controls(NC).Methods: AD(n =20) and MCI(n=30) patients were recruited at the Memory Clinic of Neurology Department in Nanjing Drum Tower Hospital, and age-and sex-matched NC( n=30) were identified.MRI examinations were performed at 3 Tesla using an SENSE-8-channel phased array coil ( Achieva 3.0 T TX dual gradient and dual-source parallel RF excitation and transmission technology, Philips Medical Systems, The Netherlands).The structural MRI and 2D-PRESS 1H MRS data were acquired and preprocessed.Hippocampal volume was calculated by FreeSurFer.And the ratio of N-acetylaspartate ( NAA)/creatine( Cr) and myoinositol( mI)/Cr in hippocampal subfields ( head, body and tail) were calculated in Philips Work-station.The hippocampal volume and metabolite ratios were compared in AD, MCI and NC group. And correlation analysis between volume and metabolite ratios was also included in this study.Results: Bilateral hippocampal volumes were significantly reduced in AD compared with MCI and NC ( P0.05 ) .Compared with MCI and NC, NAA/Cr ratio in AD was significantly decreased in right hippocampus(head) and left hippocampus(head, body and tail ) , mI/Cr ratio in AD was significantly increased in left hippocampus ( head and tail ) and right hippocampus(head, body and tail)(P<0.05).Compared with NC, MCI patients showed significantly decreased NAA/Cr ratio and increased mI/Cr ratio in left hippocampus head ( P <0.05 ) .There were significant positive correlations between bilateral hippocampal volumes and MMSE, MoCA score( P<0.05) .Left hippocampal volume was positively correlated with NAA/Cr ratio and negatively correlated with mI/Cr ratio in left hippocampal head (P<0.05).Conclusion:Bilateral hippocampal volumes significantly reduce in AD.Hippocampal atrophy seems not obvious in MCI stage while changes of NAA/Cr and mI/Cr ratio in left hippocampal head could be detected, indicating that hippocampal metabolic changes

  5. Giant magnon on deformed AdS3×S3

    Science.gov (United States)

    Khouchen, Malak; KlusoÅ, Josef

    2014-09-01

    We study giant magnon solutions for strings moving on a deformed AdS3×S3 background. We impose a conformal gauge on the Polyakov action and proceed with solving the Virasoro constraints. The expressions of the conserved charge J and the energy of a single magnon excitation are then computed. Then we determine the dispersion relation of a giant magnon in the infinite J limit configuration and we find that for κ =0 it reduces to the celebrated Hofman-Maldacena dispersion relation.

  6. Giant Magnon on Deformed AdS(3)xS(3)

    CERN Document Server

    Khouchen, Malak

    2014-01-01

    We study giant magnon solutions for strings moving on a deformed AdS(3)xS(3) background. We impose a conformal gauge on the Polyakov action and proceed with solving the Virasoro constraints. The expressions of the conserved charge J and the energy of a single magnon excitation are then computed. Then we determine the dispersion relation in the infinite J limit configuration and we find that it reduces to celebrated Hofman-Maldacena dispersion relation when the deformation parameter goes to zero.

  7. Self-dual warped AdS3 black holes

    Science.gov (United States)

    Chen, Bin; Ning, Bo

    2010-12-01

    We study a new class of solutions of three-dimensional topological massive gravity. These solutions can be taken as nonextremal black holes, with their extremal counterparts being discrete quotients of spacelike warped AdS3 along the U(1)L isometry. We study the thermodynamics of these black holes and show that the first law is satisfied. We also show that for consistent boundary conditions, the asymptotic symmetry generators form only one copy of the Virasoro algebra with central charge cL=(4νℓ)/(G(ν2+3)), with which the Cardy formula reproduces the black hole entropy. We compute the real-time correlators of scalar perturbations and find a perfect match with the dual conformal field theory (CFT) predictions. Our study provides a novel example of warped AdS/CFT correspondence: the self-dual warped AdS3 black hole is dual to a CFT with nonvanishing left central charge. Moreover, our investigation suggests that the quantum topological massive gravity asymptotic to the same spacelike warped AdS3 in different consistent ways may be dual to different two-dimensional CFTs.

  8. AdS solutions through transgression

    Energy Technology Data Exchange (ETDEWEB)

    Donos, A. [Deutsches Elektronen-Synchrotron (DESY), Hamburg (Germany). Theory Group; Gauntlett, J.P. [Imperial College, London (United Kingdom). Blackett Lab.]|[Imperial College, London (United Kingdom). The Institute for Mathematical Sciences; Kim, Nakwoo [Kyung Hee Univ., Seoul (Korea). Dept. of Physics and Research Inst. of Basic Science

    2008-07-15

    We present new classes of explicit supersymmetric AdS{sub 3} solutions of type IIB supergravity with non-vanishing five-form flux and AdS{sub 2} solutions of D=11 supergravity with electric four-form flux. The former are dual to two-dimensional SCFTs with (0,2) supersymmetry and the latter to supersymmetric quantum mechanics with two supercharges. We also investigate more general classes of AdS{sub 3} solutions of type IIB supergravity and AdS{sub 2} solutions of D=11 supergravity which in addition have non-vanishing three-form flux and magnetic four-form flux, respectively. The construction of these more general solutions makes essential use of the Chern-Simons or ''transgression'' terms in the Bianchi identity or the equation of motion of the field strengths in the supergravity theories. We construct infinite new classes of explicit examples and for some of the type IIB solutions determine the central charge of the dual SCFTs. The type IIB solutions with non-vanishing three-form flux that we construct include a two-torus, and after two T-dualities and an S-duality, we obtain new AdS3 solutions with only the NS fields being non-trivial. (orig.)

  9. ADS National Programmes: Republic of Korea

    International Nuclear Information System (INIS)

    ADS research of Korea was carried out at KAERI (Korea Atomic Energy Research Institute) for the transmutation of long lived nuclides in spent fuels. The KAERI ADS system was called HYPER (HYbrid Power Extraction Reactor). The HYPER research was carried out as a 10 year nuclear research programme funded by the government. The ADS research of KAERI consisted of 3 phases. A basic concept of HYPER was established in the first phase (1997– 2000) of the development. The key technologies related to HYPER was studied in the second phase (2001–2003) while upgrading the design. The conceptual design of HYPER core was completed in the third phase (2004–2006). The research of key technologies was continued in the third phase. The research results can be summarized in three categories: Design and analysis; Fuel experiment; Pb-Bi experiment

  10. Stability of charged global AdS4 spacetimes

    Science.gov (United States)

    Arias, Raúl; Mas, Javier; Serantes, Alexandre

    2016-09-01

    We study linear and nonlinear stability of asymptotically AdS4 solutions in Einstein-Maxwell-scalar theory. After summarizing the set of static solutions we first examine thermodynamical stability in the grand canonical ensemble and the phase transitions that occur among them. In the second part of the paper we focus on nonlinear stability in the microcanonical ensemble by evolving radial perturbations numerically. We find hints of an instability corner for vanishingly small perturbations of the same kind as the ones present in the uncharged case. Collapses are avoided, instead, if the charge and mass of the perturbations come to close the line of solitons. Finally we examine the soliton solutions. The linear spectrum of normal modes is not resonant and instability turns on at extrema of the mass curve. Linear stability extends to nonlinear stability up to some threshold for the amplitude of the perturbation. Beyond that, the soliton is destroyed and collapses to a hairy black hole. The relative width of this stability band scales down with the charge Q, and does not survive the blow up limit to a planar geometry.

  11. Stability of Charged Global AdS$_4$ Spacetimes

    CERN Document Server

    Arias, Raúl; Serantes, Alexandre

    2016-01-01

    We study linear and nonlinear stability of asymptotically AdS$_4$ solutions in Einstein-Maxwell-scalar theory. After summarizing the set of static solutions we first examine thermodynamical stability in the grand canonical ensemble and the phase transitions that occur among them. In the second part of the paper we focus on nonlinear stability in the microcanonical ensemble by evolving radial perturbations numerically. We find hints of an instability corner for vanishingly small perturbations of the same kind as the ones present in the uncharged case. Collapses are avoided, instead, if the charge and mass of the perturbations come to close the line of solitons. Finally we examine the soliton solutions. The linear spectrum of normal modes is not resonant and instability turns on at extrema of the mass curve. Linear stability extends to nonlinear stability up to some threshold for the amplitude of the perturbation. Beyond that, the soliton is destroyed and collapses to a hairy black hole. The relative width of t...

  12. Adding Natural Areas to Social Indicators of Intra-Urban Health Inequalities among Children: A Case Study from Berlin, Germany

    Science.gov (United States)

    Kabisch, Nadja; Haase, Dagmar; Annerstedt van den Bosch, Matilda

    2016-01-01

    Research suggests that there is a relationship between the health of urban populations and the availability of green and water spaces in their daily environment. In this paper, we analyze the potential intra-urban relationships between children’s health determinants and outcomes and natural areas in Berlin, Germany. In particular, health indicators such as deficits in viso-motoric development in children are related to environmental indicators such as the natural area cover, natural area per capita and distance to natural areas; however, these indicators are also correlated with social determinants of health. The methodological approach used in this study included bivariate and multivariate analyses to explore the relations between health inequalities and social, socio-economic, and land use parameters. The results on a sub-district level indicated that there was a correlation between natural areas and social health determinants, both of which displayed a certain intra-urban spatial pattern. In particular, a lower percentage of natural area cover was correlated with deficits in viso-motoric development. However, results with percentage of natural area cover and per capita natural area with childhood overweight were not conclusive. No significant correlation was found for percentage of natural area cover and overweight, while significant negative correlation values were found between overweight and per capita natural area. This was identified particularly in the districts that had lower social conditions. On the other hand, the districts with the highest social conditions had the comparatively lowest levels of complete measles immunization. This study may facilitate public health work by identifying the urban areas in which the strengthening of health resources and actions should be prioritized and also calls for the inclusion of natural areas among the social health indicators included in intra-urban health inequality tools. PMID:27527197

  13. Adding Natural Areas to Social Indicators of Intra-Urban Health Inequalities among Children: A Case Study from Berlin, Germany.

    Science.gov (United States)

    Kabisch, Nadja; Haase, Dagmar; Annerstedt van den Bosch, Matilda

    2016-01-01

    Research suggests that there is a relationship between the health of urban populations and the availability of green and water spaces in their daily environment. In this paper, we analyze the potential intra-urban relationships between children's health determinants and outcomes and natural areas in Berlin, Germany. In particular, health indicators such as deficits in viso-motoric development in children are related to environmental indicators such as the natural area cover, natural area per capita and distance to natural areas; however, these indicators are also correlated with social determinants of health. The methodological approach used in this study included bivariate and multivariate analyses to explore the relations between health inequalities and social, socio-economic, and land use parameters. The results on a sub-district level indicated that there was a correlation between natural areas and social health determinants, both of which displayed a certain intra-urban spatial pattern. In particular, a lower percentage of natural area cover was correlated with deficits in viso-motoric development. However, results with percentage of natural area cover and per capita natural area with childhood overweight were not conclusive. No significant correlation was found for percentage of natural area cover and overweight, while significant negative correlation values were found between overweight and per capita natural area. This was identified particularly in the districts that had lower social conditions. On the other hand, the districts with the highest social conditions had the comparatively lowest levels of complete measles immunization. This study may facilitate public health work by identifying the urban areas in which the strengthening of health resources and actions should be prioritized and also calls for the inclusion of natural areas among the social health indicators included in intra-urban health inequality tools.

  14. Adding Natural Areas to Social Indicators of Intra-Urban Health Inequalities among Children: A Case Study from Berlin, Germany.

    Science.gov (United States)

    Kabisch, Nadja; Haase, Dagmar; Annerstedt van den Bosch, Matilda

    2016-01-01

    Research suggests that there is a relationship between the health of urban populations and the availability of green and water spaces in their daily environment. In this paper, we analyze the potential intra-urban relationships between children's health determinants and outcomes and natural areas in Berlin, Germany. In particular, health indicators such as deficits in viso-motoric development in children are related to environmental indicators such as the natural area cover, natural area per capita and distance to natural areas; however, these indicators are also correlated with social determinants of health. The methodological approach used in this study included bivariate and multivariate analyses to explore the relations between health inequalities and social, socio-economic, and land use parameters. The results on a sub-district level indicated that there was a correlation between natural areas and social health determinants, both of which displayed a certain intra-urban spatial pattern. In particular, a lower percentage of natural area cover was correlated with deficits in viso-motoric development. However, results with percentage of natural area cover and per capita natural area with childhood overweight were not conclusive. No significant correlation was found for percentage of natural area cover and overweight, while significant negative correlation values were found between overweight and per capita natural area. This was identified particularly in the districts that had lower social conditions. On the other hand, the districts with the highest social conditions had the comparatively lowest levels of complete measles immunization. This study may facilitate public health work by identifying the urban areas in which the strengthening of health resources and actions should be prioritized and also calls for the inclusion of natural areas among the social health indicators included in intra-urban health inequality tools. PMID:27527197

  15. HCMV AD169株大鼠慢性感染模型的初步探讨%An experimental study of rat infeected with human cytomegalovirus AD168 strain

    Institute of Scientific and Technical Information of China (English)

    孟红; 孙德刚; 王健; 刘菊华; 孙广莲; 李焱; 张家驹; 张维东

    2000-01-01

    Objective To Study the sensitivity of rat to human cytomegalovirus (HCMV) infection and to es-tablish a stable animal model. Methods Two kinds of rat experiments were carried out: 1)30 SD rats were divided intothree groups randomly,they were virus inoculated group,inactivated virus inoculated group and the normal rat group re-spectively; 2)40 Wistar rats were randomly divided into two groups,they were the virus inoculated group and the inacti-vated virus inoculated group. All the rats were inoculated through tail vein.90 d later,the rat's tissue lesions were ob-served by pathological techniques,HCMV antigen was detected by immunohistochemical method and the HCMV DNA wasanalyzed by in situ hybridization. Results The extensive pathological damages in tissues of HCMV infected rats wereobserved. Meanwhile,the viral antigen and viral DNA were also demonstrated in many tissues of HCMV infected rats.Conchusion Rat is sensitive to iridectiion of HCMV AD1168 strain, hut, as an animal model study,we stoll have a lot of works to do.%目的 探讨人巨细胞病毒(Human Cytomegalovirus,HCMV)感染大鼠的敏感性和稳定性,探讨建立大鼠感染HCMV动物模型的可行性。方法 第一次动物试验:SD大鼠30只,随机均分为3组,分别为接种病毒组、灭活病毒组和正常对照组,病毒接种途径为尾静脉注射;第二次动物试验:Wistar大鼠40只,分别为接种病毒组(20只)、灭活病毒组(20只),病毒接种途径同第一次动物试验。两次试验动物均于90d后分别以病理学方法 研究动物组织损伤特点,以免疫组化方法 检查病毒抗原,原位杂交方法 检测动物组织细胞中HCMV基因。结果 两次静脉途径接种HCMV AD169株90d的动物,组织发生广泛病理损害,免疫组化方法 和原位杂交方法 在多种组织细胞内查到HCMV抗原和基因表达。结论 HCMV AD169株可感染健康大鼠,可望作为HCMV动物慢性感染模型。

  16. International Programmes on ADS: IAEA

    International Nuclear Information System (INIS)

    The IAEA recognizes that there are four major challenges facing the long term development of nuclear energy as a part of the world’s energy mix: improvement of the economic competitiveness, meeting increasingly stringent safety requirements, adhering to the criteria of sustainable development, and public acceptance. Meeting the sustainability criteria is the driving force behind IAEA’s activity in the area of innovative transmutation reactor technology development and, in particular, Accelerator Driven Systems. The framework for all the IAEA activities in the ADS area is the Technical Working Group on Fast Reactors (TWG-FR). In response to strong common R&D needs in the Member States, the TWG-FR acts as a catalyst for international information exchange and collaborative R&D. It provides a forum for exchange of non-commercial scientific and technical information, and a forum for international cooperation on generic research and development programmes on advances in fast reactors and fast spectrum accelerator driven systems. Its present members are the following 15 IAEA Member States: Belarus, Brazil, China, France, Germany, India, Italy, Japan, Kazakhstan, Republic of Korea, Russian Federation, Sweden, Switzerland, United Kingdom, and United States of America, as well as 3 international organizations: ISTC, OECD-NEA, and EU (EC). As observers, the TWG-FR has welcomed Argentina and Belgium. Last but not least, the IAEA is providing the ADS Research and Development Database. It contains information about ADS related R&D programmes, existing and planned experimental facilities as well as programmes, methods and data development efforts, design studies, and so forth

  17. Study of the effect of nano-sized precipitates on the mechanical properties of boron-added low-carbon steels by neutron scattering techniques.

    Science.gov (United States)

    Seong, B S; Cho, Y R; Shin, E J; Kim, S I; Choi, S-H; Kim, H R; Kim, Y J

    2008-10-01

    Small-angle neutron scattering (SANS) and neutron powder diffraction (ND) techniques were used to study quantitatively the effect of nano-sized precipitates and boron addition on the mechanical properties of low-carbon steels. SANS was used to evaluate nano-sized precipitates, smaller than about 600 A in diameter, and ND was used to determine the weight fraction of the cementite precipitates. Fine core-shell structured spherical precipitates with an average radius of ~50 A, such as MnS and/or CuS, surrounded by BN layers were observed in the boron-added (BA) low-carbon steels; fine spherical precipitates with an average radius of ~48 A were mainly observed in the boron-free (BF) low-carbon steels. In the BA steels, the number of boron precipitates, such as BN, Fe(3)(C,B) and MnS, surrounded by BN layers increased drastically at higher hot-rolling temperatures. The volume fraction of the fine precipitates of the BA steels was higher than that of the BF steels; this difference is related to the rapid growth of the BN layers on the MnS and CuS precipitates. Boron addition to low-carbon steels resulted in a reduction in strength and an improvement in elongation; this behaviour is related to the reduction of the solute carbon and the nitrogen contents in the ferrite matrix caused by the precipitation of BN, as well by the increase in the volume fraction of the cementites. PMID:19461851

  18. Kolmogorov-Zakharov spectrum in AdS gravitational collapse.

    Science.gov (United States)

    de Oliveira, H P; Pando Zayas, Leopoldo A; Rodrigues, E L

    2013-08-01

    We study black hole formation during the gravitational collapse of a massless scalar field in asymptotically D-dimensional anti-de Sitter AdS(D) spacetimes for D = 4, 5. We conclude that spherically symmetric gravitational collapse in asymptotically AdS spaces is turbulent and characterized by a Kolmogorov-Zakharov spectrum. Namely, we find that after an initial period of weakly nonlinear evolution, there is a regime where the power spectrum of the Ricci scalar evolves as ω(-s) with the frequency, ω, and s ≈ 1.7 ± 0.1.

  19. Refined holographic entanglement entropy for the AdS solitons and AdS black holes

    International Nuclear Information System (INIS)

    We consider the refinement of the holographic entanglement entropy for the holographic dual theories to the AdS solitons and AdS black holes, including the corrected ones by the Gauss–Bonnet term. The refinement is obtained by extracting the UV-independent piece of the holographic entanglement entropy, the so-called renormalized entanglement entropy which is independent of the choices of UV cutoff. Our main results are: (i) the renormalized entanglement entropies of the AdSd+1 soliton for d=4,5 are neither monotonically decreasing along the RG flow nor positive-definite, especially around the deconfinement/confinement phase transition; (ii) there is no topological entanglement entropy for AdS5 soliton even with Gauss–Bonnet correction; (iii) for the AdS black holes, the renormalized entanglement entropy obeys an expected volume law at IR regime, and the transition between UV and IR regimes is a smooth crossover even with Gauss–Bonnet correction; (iv) based on AdS/MERA conjecture, we postulate that the IR fixed-point state for the non-extremal AdS soliton is a trivial product state

  20. Predicting AD conversion

    DEFF Research Database (Denmark)

    Liu, Yawu; Mattila, Jussi; Ruiz, Miguel �ngel Mu�oz;

    2013-01-01

    To compare the accuracies of predicting AD conversion by using a decision support system (PredictAD tool) and current research criteria of prodromal AD as identified by combinations of episodic memory impairment of hippocampal type and visual assessment of medial temporal lobe atrophy (MTA) on MRI...

  1. Gut-related studies of radionuclide toxicity

    International Nuclear Information System (INIS)

    This project is concerned with the behavior of radioactive materials that mayu be ingested as a consequence of a reactor accident, unavoidable occupational exposure, or after release to the environment and incorporation into the food chain. Current emphasis is on evaluating hazards from ingested actinides as a function of animal age, species, nutrition, and diet, or chemicophysical state of the actinide. We are also concerned with the behavior of actinides that are inhaled and pass through the gastrointestinal (GI) tract after clearance from the lungs. Recent experiments showed that adult swine absorbed more 238Pu nitrate than had previously been indicated in studies with 239Pu nitrate, three times more than is absorbed by rats. Absorption of 238Pu by rats on a vitamin-D-deficient diet was about 10 times higher than absorption by rats on a balanced diet. Studies on the effect of chemical form on actinide absorption showed that the citrate forms of 238Pu, 241Am and 244Cm were transported in higher quantities than the nitrate forms across the intestine. Citrate had no effect on the 237Np transport, but the mass of isotope administered was found to be important. Absorption by neonates was inversely related to the mass of neptunium gavaged, in contrast to the effect of mass on neptunium absorption by adult rats. Organic binding of 238Pu in liver tissue, in situ, resulted in decreased absorption by adult or neonatal rats. These results demonstrate that animal age, species and nutritional state are important factors in determining GI absorption of actinide compounds. Chemical form and oxidation state also influence transport. These effects vary with animal age and with the actinide in question

  2. Association Between Media Dose, Ad Tagging, and Changes in Web Traffic for a National Tobacco Education Campaign: A Market-Level Longitudinal Study

    Science.gov (United States)

    Davis, Kevin C; Patel, Deesha; Rodes, Robert; Beistle, Diane

    2016-01-01

    Background In 2012, the US Centers for Disease Control and Prevention (CDC) launched Tips From Former Smokers (Tips), the first federally funded national tobacco education campaign. In 2013, a follow-up Tips campaign aired on national cable television networks, radio, and other channels, with supporting digital advertising to drive traffic to the Tips campaign website. Objective The objective of this study was to use geographic and temporal variability in 2013 Tips campaign television media doses and ad tagging to evaluate changes in traffic to the campaign website in response to specific doses of campaign media. Methods Linear regression models were used to estimate the dose-response relationship between weekly market-level television gross rating points (GRPs) and weekly Web traffic to the Tips campaign website. This relationship was measured using unique visitors, total visits, and page views as outcomes. Ad GRP effects were estimated separately for ads tagged with the Tips campaign website URL and 1-800-QUIT-NOW. Results In the average media market, an increase of 100 television GRPs per week for ads tagged with the Tips campaign website URL was associated with an increase of 650 unique visitors (Padvertising efforts on consumers’ use of campaign-specific websites. PMID:26887959

  3. Ts...sT transformation on $AdS_{5}\\times S^{5}$ background

    CERN Document Server

    Rashkov, R C; Yang, Y; Yang, Yi

    2005-01-01

    In this paper we consider a simple generalization of Lunin and Maldacena procedure of generating new string backgrounds based on TsT-transformations. We study multi-shift $Ts... sT$ transformations applied to backgrounds with at least two U(1) isometries. We prove that the string currents in any two backgrounds related by Ts...sT-transformations are equal. Performing this procedure to the $AdS_{5}\\times S^{5}$ we find a new background and study some properties of the semiclassical strings.

  4. International Programmes on ADS: European Commission

    International Nuclear Information System (INIS)

    Euratom research projects related to the design and the use of ADS facilities started in the 4th Framework Programme (FP4) (1996–2001) with the project ‘Impact of Accelerator Based Technologies on Nuclear Fission Safety—IABAT’. The overall objective of the IABAT project was a preliminary assessment of the potential of Accelerator Driven Systems for transmutation of radioactive waste and, additionally, for nuclear energy production with minimum waste generation. This first project was followed by a much larger ADS oriented programmes in the FP5 (2002–2005), FP6 (2005–2010) and FP7 (2008–2013). In the frame of the FP6, special attention was devoted to the EUROTRANS integrated Project (2005–2010), dedicated to study the transmutation of high level radioactive waste in an ADS. Based on the three FP5 Clusters FUETRA, BASTRA and TESTRA together with the PDS-XADS Project, the EUROTRANS Project was aimed to carry out a first advanced design of an approximately 50 to 100 MWth eXperimental facility (realization in a short term, say about 10 years) demonstrating the technical feasibility of Transmutation in an ADS (XT ADS), as well as to accomplish a generic conceptual design (several 100 MWth) of a modular European Facility for Industrial Transmutation (EFIT) (realisation in the long term)

  5. AdS nonlinear instability: moving beyond spherical symmetry

    CERN Document Server

    Dias, Oscar J C

    2016-01-01

    Anti-de Sitter (AdS) is conjectured to be nonlinear unstable to a weakly turbulent mechanism that develops a cascade towards high frequencies, leading to black hole formation [1,2]. We give evidence that the gravitational sector of perturbations behaves differently from the scalar one studied in [2]. In contrast with [2], we find that not all gravitational normal modes of AdS can be nonlinearly extended into periodic horizonless smooth solutions of the Einstein equation. In particular, we show that even seeds with a single normal mode can develop secular resonances, unlike the spherically symmetric scalar field collapse studied in [2]. Moreover, if the seed has two normal modes, more than one resonance can be generated at third order, unlike the spherical collapse of [2]. We also show that weak turbulent perturbative theory predicts the existence of direct and inverse cascades, with the former dominating the latter for equal energy two-mode seeds.

  6. rAd-p53对人肝癌细胞放射敏感性影响的实验研究%Experimental study of the effects of rAd-p53 on theradiosensitivity of human hepatocellular carcionoma

    Institute of Scientific and Technical Information of China (English)

    陶振超; 邱俊; 钱立庭; 王明明; 吴爱东; 闫冰

    2012-01-01

    To observe the effect and difference of rAd-p53 on the radiosensitivity for human hepatocellular carcionoma( HCC ). Methods Two HCC cell lines with different p53 genetic statuses, PLC/PRF/5( MT p53 ) and HepG2( WT p53 ) were infected with recombinant adenovirus carrying wild-type( WT ) p53 gene( rAd-p53 ) and Ad-EGFP, and cell survival was evaluated by MTT; Radiosensitivity was evaluated by clonogenic assay. Cell apoptosis was assayed by flow cytometry. Results 48 h after infection efficiency of 15MOI values of rAd-p53 to PLC/PRF/5 and HepG2 cells, and cell survival rates of PLC/PRF/5 and HepG2 cells were( 7. 30 ± 1. 78 )% and ( 11.51 ±1. 53 )%. The transduction efficiency was gradually increased with the infection time or virus dosage in-creased( P <0. 01 ). SER value of HepG2 and PLC/PRF/5 were 1. 24 and 1. 52 by clonogenic assay,cell apoptosis was( 22. 19 ± 1. 04 )% and( 30. 36 ±2. 74 )% respectively and the effects of rAd-p53 group was stronger than oth-ers( P <0. 01 ). Conclusion rAd-p53 can significantly inhibit proliferation, induce cell apoptosis and increase radiosensitivity of HCC, but the aforesaid efficacy of rAd-p53 in PLC/PRF/5 cells( MT p53 ) is stronger than that in HepG2 cells( WT P53 ).%目的 探讨重组p53腺病毒(rAd-p53)对不同p53基因型的肝癌细胞放射敏感性的影响及差异.方法 用rAd-p53、Ad-EGFP(构建方式及载体的结构与rAd-p53完全相同,仅目的 基因不同的腺病毒),分别感染人肝癌细胞HepG2(p53野生型)和人肝癌细胞PLC/PRF/5(p53突变型),MTT法检测细胞存活率;不同剂量X射线照射克隆形成率检测细胞放射敏感性,流式细胞仪检测细胞凋亡.结果 15MOI rAd-p53感染48 h后,2种细胞生长抑制率分别为(7.30±1.78)%、(11.51±1.53)%,并且随着病毒滴度或感染时间的增加,生长抑制效应亦逐渐增强(P<0.01); HepG2和PLC/PRF/5细胞放射增敏比(SER值)分别为1.24和1.52;细胞凋亡率分别为(22.19±1.04)%、(30.36±2.74)%;均明显高于空白组和Ad

  7. Alday-Maldacena duality and AdS Plateau problem

    OpenAIRE

    Morozov, A.

    2008-01-01

    A short summary of approximate approach to the study of minimal surfaces in AdS, based on solving Nambu-Goto equations iteratively. Today, after partial denunciation of the BDS conjecture, this looks like the only constructive approach to understanding the ways of its possible modification and thus to saving the Alday-Maldacena duality. Numerous open technical problems are explicitly formulated throughout the text.

  8. Winding Strings in AdS_3

    CERN Document Server

    Minces, P; Minces, Pablo; Nunez, Carmen

    2006-01-01

    Correlation functions of one-unit spectral flowed states in string theory on AdS_3 are considered. We present a formalism which allows to explicitly find the modified Knizhnik-Zamolodchikov and null vector equations to be satisfied by amplitudes of states in w=1 sectors. We give a precise prescription to solve this system of linear differential equations in cases that are relevant to obtain three and four point functions involving spectral flowed string states. We specifically compute three point functions with two and three one-unit spectral flowed operators and also discuss four point functions.

  9. Added value of stress related gene inductions in HepG2 cells as effect measurement in monitoring of air pollution

    Science.gov (United States)

    Nobels, Ingrid; Vanparys, Caroline; Van den Heuvel, Rosette; Vercauteren, Jordy; Blust, Ronny

    2012-08-01

    In this study we studied the effects of particulate matter samples (PM) through gene expression analysis in a routine air quality monitoring campaign by the Flemish Environment Agency (VMM, Belgium). We selected a human hepatoma (HepG2) multiple endpoint reporter assay for targeted stress related endpoint screening. Organic extracts of air samples (total suspended particles, TSP) were collected during one year in an industrial, urban and background location in Flanders, Belgium. Simultaneously, meteorological conditions (temperature, wind speed and precipitation) and particulate matter size ≤ 10 μM (PM10), organic (OC), elemental (EC) and total (TC) carbon were monitored and air samples were collected for chemical analysis (11 PAHs). Correlations between the induction of the different stress genes and the chemical pollutants were analysed. Exposure of HepG2 cells to daily air equivalents (20 m3) of organic TSP extracts revealed the dominant induction of the xenobiotic response element (Xre) and phase I (Cyp1A1) and phase II (GstYa) biotransformation enzymes. Additional effects were the induction of c-Fos, a proto-oncogen and Gadd45, a marker for cell cycle disturbance and responsive to genotoxic compounds. Inductions of other relevant pathways, such as sequestration of heavy metals, retinoids response, protein misfolding and increased cAMP levels were measured occasionally. A significant correlation was found between the genes Cyp1A1 (a typical marker for presence of PAHs and dioxin like compounds), c-Fos, Gadd45, (responsive to DNA damaging compounds) and the amount of PM10 and elemental carbon (EC) whereas no correlation was found between these genes and total PAHs content. This may suggest that the observed induction of Cyp1A1 and DNA damage related genes was provoked (partially) by other particle bound compounds (e.g. pesticides, PCBs, brominated flame retardants, dioxins, …), than PAHs. The contribution of particle bound compounds, other than PAHs might

  10. Study the Effect of Value-Added of Services Sector on Forecasting of Electricity Demand in Services Sector due to Price Reform

    OpenAIRE

    Sayed Mahdi Mostafavi; Saeed Shoauri; Seyyed Mohammad Seyyed Hosseini

    2016-01-01

    Electrical energy is as one of the important effective factors on economic growth and development. In recent decades, numerous studies in different countries to estimate and forecast electricity demand in different parts of the economy have been made. In this paper, using the method ARDL, estimation and forecasting of electricity demand in the services sector of Iran are determined for the time period from 1983 to 2012. Estimated equations show that the added value of the services sector and ...

  11. Effect of adding screening ultrasonography to screening mammography on patient recall and cancer detection rates: A retrospective study in Japan

    Energy Technology Data Exchange (ETDEWEB)

    Tohno, Eriko, E-mail: tohno@tmch.or.jp [Total Health Evaluation Center Tsukuba, 1-2, Amakubo, Tsukuba, Ibaraki 305-0005 (Japan); Umemoto, Takeshi, E-mail: umemoto@tmch.or.jp [Tsukuba Medical Center Hospital, 1-3-1, Amakubo, Tsukuba, Ibaraki 305-0005 (Japan); Sasaki, Kyoko, E-mail: kdon@za.cyberhome.ne.jp [Tsukuba Medical Center Hospital, 1-3-1, Amakubo, Tsukuba, Ibaraki 305-0005 (Japan); Morishima, Isamu, E-mail: morishima@tmch.or.jp [Tsukuba Medical Center Hospital, 1-3-1, Amakubo, Tsukuba, Ibaraki 305-0005 (Japan); Ueno, Ei, E-mail: e-ueno@tmch.or.jp [Tsukuba Medical Center Hospital, 1-3-1, Amakubo, Tsukuba, Ibaraki 305-0005 (Japan)

    2013-08-15

    Purpose: To determine whether adding screening ultrasonography to screening mammography can reduce patient recall rates and increase cancer detection rates. Materials and methods: We analyzed the results of mammography and ultrasonography breast screenings performed at the Total Health Evaluation Center Tsukuba, Japan, between April 2011 and March 2012. We also reviewed the modalities and results of diagnostic examinations from women with mammographic abnormalities who visited the Tsukuba Medical Center Hospital for further testing. Results: Of 11,753 women screened, cancer was diagnosed in 10 (0.22%) of the 4529 participants who underwent mammography alone, 23 (0.37%) of the 6250 participants who underwent ultrasonography alone, and 5 (0.51%) of the 974 participants who underwent mammography and ultrasonography. The recall rate due to mammographic abnormalities was 4.9% for women screened only with mammography and 2.6% for those screened with both modalities. The cancer detection rate was 0.22% for women screened only with mammography (positive predictive value, 4.5%) and 0.31% for those screened with both modalities (positive predictive value, 12.0%). Of the 211 lesions presenting as mammographic abnormalities investigated further, diagnostic ultrasonography found no abnormalities in 63 (29.9%) and benign findings in 69 (33.7%). The rest 36.4% needed mammography, cytological or histological examinations or follow-up in addition to diagnostic ultrasonography. Conclusions: It is possible to reduce the recall rate in screening mammography by combining mammography and ultrasonography for breast screening.

  12. Effect of adding screening ultrasonography to screening mammography on patient recall and cancer detection rates: A retrospective study in Japan

    International Nuclear Information System (INIS)

    Purpose: To determine whether adding screening ultrasonography to screening mammography can reduce patient recall rates and increase cancer detection rates. Materials and methods: We analyzed the results of mammography and ultrasonography breast screenings performed at the Total Health Evaluation Center Tsukuba, Japan, between April 2011 and March 2012. We also reviewed the modalities and results of diagnostic examinations from women with mammographic abnormalities who visited the Tsukuba Medical Center Hospital for further testing. Results: Of 11,753 women screened, cancer was diagnosed in 10 (0.22%) of the 4529 participants who underwent mammography alone, 23 (0.37%) of the 6250 participants who underwent ultrasonography alone, and 5 (0.51%) of the 974 participants who underwent mammography and ultrasonography. The recall rate due to mammographic abnormalities was 4.9% for women screened only with mammography and 2.6% for those screened with both modalities. The cancer detection rate was 0.22% for women screened only with mammography (positive predictive value, 4.5%) and 0.31% for those screened with both modalities (positive predictive value, 12.0%). Of the 211 lesions presenting as mammographic abnormalities investigated further, diagnostic ultrasonography found no abnormalities in 63 (29.9%) and benign findings in 69 (33.7%). The rest 36.4% needed mammography, cytological or histological examinations or follow-up in addition to diagnostic ultrasonography. Conclusions: It is possible to reduce the recall rate in screening mammography by combining mammography and ultrasonography for breast screening

  13. Universal isolation in the AdS landscape

    CERN Document Server

    Danielsson, U H; Vargas, S C

    2016-01-01

    We study the universal conditions for quantum non-perturbative stability against bubble nucleation for pertubatively stable AdS vacua based on positive energy theorems. We also compare our analysis with the pre-existing ones in the literature carried out within the thin-wall approximation. The aforementioned criterion is then tested in two explicit examples describing massive type IIA string theory compactified on $S^3$ and $S^3\\,\\times\\,S^3$, respectively. The AdS landscape of both classes of compactifications is known to consist of a set of isolated points. The main result is that all critical points respecting the Breitenlohner-Freedaman (BF) bound also turn out be stable at a non-perturbative level. Finally, we speculate on the possible universal features that may be extracted from the above specific examples.

  14. Thermodynamics of Einstein-Proca AdS Black Holes

    CERN Document Server

    Liu, Hai-Shan; Pope, C N

    2014-01-01

    We study static spherically-symmetric solutions of the Einstein-Proca equations in the presence of a negative cosmological constant. We show that the theory admits solutions describing both black holes and also solitons in an asymptotically AdS background. Interesting subtleties can arise in the computation of the mass of the solutions and also in the derivation of the first law of thermodynamics. We make use of holographic renormalisation in order to calculate the mass, even in cases where the solutions have a rather slow approach to the asymptotic AdS geometry. By using the procedure developed by Wald, we derive the first law of thermodynamics for the black hole and soliton solutions. This includes a non-trivial contribution associated with the Proca "charge." The solutions cannot be found analytically, and so we make use of numerical integration techniques to demonstrate their existence.

  15. Perturbative entanglement thermodynamics for AdS spacetime: Renormalization

    CERN Document Server

    Mishra, Rohit

    2015-01-01

    We study the effect of charged excitations in the AdS spacetime on the first law of entanglement thermodynamics. It is found that `boosted' AdS black holes give rise to a more general form of first law which includes chemical potential and charge density. To obtain this result we have to resort to a second order perturbative calculation of entanglement entropy for small size subsystems. At first order the form of entanglement law remains unchanged even in the presence of charged excitations. But the thermodynamic quantities have to be appropriately `renormalized' at the second order due to the corrections. We work in the perturbative regime where $T_{thermal}\\ll T_E$.

  16. The Mixed Phase of Charged AdS Black Holes

    Directory of Open Access Journals (Sweden)

    Piyabut Burikham

    2016-01-01

    Full Text Available We study the mixed phase of charged AdS black hole and radiation when the total energy is fixed below the threshold to produce a stable charged black hole branch. The coexistence conditions for the charged AdS black hole and radiation are derived for the generic case when radiation particles carry charge. The phase diagram of the mixed phase is demonstrated for both fixed potential and charge ensemble. In the dual gauge picture, they correspond to the mixed phase of quark-gluon plasma (QGP and hadron gas in the fixed chemical potential and density ensemble, respectively. In the nuclei and heavy-ion collisions at intermediate energies, the mixed phase of exotic QGP and hadron gas could be produced. The mixed phase will condense and evaporate into the hadron gas as the fireball expands.

  17. Reconstructions of Circulation in the Northeastern Pacific and Western North America since 1500 A.D.: Relation to Precipitation and Fire Conditions in California

    Science.gov (United States)

    Zorita, Eduardo; Wahl, Eugene; Trouet, Valerie

    2016-04-01

    A reconstruction of the position of the North Pacific Jet Stream (NPJ) in wintertime over the past 500 years is. Reconstruction of NPJ behavior is driven by an analog process that employs existing paleoclimate field reconstructions of winter temperature, summer precipitation and summer soil moisture from western North America to select climate model states in millennial climate simulations that are closest to the field reconstructions. The skill of the reconstruction method is tested against the 20CR meteorological reanalysis. All three types of proxy sets individually contribute to the skill in the reconstruction of the winter atmospheric circulation. The NPJ reconstruction is also evaluated in relation to dry and wet extremes in California and extremes of Sierra Nevada fire activity. Results indicate that fire and precipitation extremes are both closely linked with NPJ winter position, with characteristic wet/low fire and dry/high fire NPJ spatial features in the northeastern Pacific adjacent to western North America. The meridional profiles of zonal wind at 200 hPa height can be classified according to winters belonging to dry and wet hydrological years and also according to summers with high or low fire activity. This classification indicates that in wet years and low-fire years the jet stream is more intense, more zonally oriented with peak winds occurring at lower latitudes. The opposite configuration occurs in dry, high-fire, years, with a more meandering jet stream peaking at higher latitudes. These features are in turn evaluated in future climate model scenarios using directly comparable transient integrations that cover the past millennium, the instrumental period, and the 21st century. Relatively wet/low fire regional conditions are reasonably possible in the later 21st century under a high greenhouse gas forcing regime (RCP 8.5), even though temperatures rise significantly. The implication of this combination of conditions in the Sierra Nevada is that

  18. Rationale and design of the AdRem study : Evaluating the effects of blood pressure lowering and intensive glucose control on vascular retinal disorders in patients with type 2 diabetes mellitus

    NARCIS (Netherlands)

    Stolk, Ronald P.; Vingerling, Johannes R.; Cruickshank, J. Kennedy; Hughes, Alun D.; Stanton, Alice; Lu Juming, [No Value; Patel, Anushka; Thom, Simon A. McG.; Grobbee, Diederick E.; Lu, J.M.

    2007-01-01

    The ADVANCE Retinal Measurements (AdRem) Study is a large intervention study evaluating the effects of target driven intensive glucose control and placebo controlled blood pressure lowering on retinal vascular changes. AdRem is a sub-study of the ADVANCE Study (Action in Diabetes and Vascular diseas

  19. Catalog of NASA-Related Case Studies

    Data.gov (United States)

    National Aeronautics and Space Administration — The OCKO has developed over 50 case studies to enhance learning at workshops, training, retreats and conferences. Case studies make mission knowledge attractive and...

  20. Causality and the conformal boundary of AdS in real-time holography

    CERN Document Server

    Enciso, Alberto

    2012-01-01

    We consider the holographic prescription problem in a (Lorentzian) AdS background, deriving from first principles the explicit formulas that relate the field at infinity with the field in the bulk. In contrast with the previous studies of the "real-time" holography problem, our derivation uses purely classical arguments that involve causality, as in the usual treatment of the holographic prescription problem in Wick-rotated spaces of Euclidean signature. We show that there is a unique propagator that preserves causality and see that this provides a simple picture of the relationship between the bulk manifold and its conformal boundary.

  1. Wireless Ad Hoc Networks

    Directory of Open Access Journals (Sweden)

    Hong-Chuan Yang

    2007-01-01

    Full Text Available We study the energy-efficient configuration of multihop paths with automatic repeat request (ARQ mechanism in wireless ad hoc networks. We adopt a cross-layer design approach and take both the quality of each radio hop and the battery capacity of each transmitting node into consideration. Under certain constraints on the maximum tolerable transmission delay and the required packet delivery ratio, we solve optimization problems to jointly schedule the transmitting power of each transmitting node and the retransmission limit over each hop. Numerical results demonstrate that the path configuration methods can either significantly reduce the average energy consumption per packet delivery or considerably extend the average lifetime of the multihop route.

  2. SUSY properties of warped AdS$_3$

    CERN Document Server

    Jeong, Jaehoon; Yoshida, Kentaroh

    2014-01-01

    We examine supersymmetric properties of null-warped AdS$_3$, or alternatively Schrodinger geometries, dual to putative warped CFTs in two dimensions. We classify super Schrodinger subalgebras of the superalgebra psu(1, 1$|$2) $\\oplus$ psu(1, 1$|$2) , corresponding to the superconformal algebra of the AdS$_3 \\times$ S$^3$ geometry. We comment on geometric realisations and provide a string theory description with enhanced supersymmetry in terms of intersecting D3-branes. For type IIB supergravity solutions based on T$^{1,1}$, we consider the relationship between five-dimensional Schrodinger solutions and their three-dimensional null-warped counterparts, corresponding to R symmetry twists. Finally, we study a family of null-warped AdS$_3$ solutions in a setting where there is an ambiguity over the R symmetry and confirm that, for examples admitting a KK reduction to three dimensions, the minimisation of a real superpotential of the three-dimensional gauged supergravity captures the central charge and R symmetry.

  3. AdS3: the NHEK generation

    Science.gov (United States)

    Bena, Iosif; Heurtier, Lucien; Puhm, Andrea

    2016-05-01

    It was argued in [1] that the five-dimensional near-horizon extremal Kerr (NHEK) geometry can be embedded in String Theory as the infrared region of an infinite family of non-supersymmetric geometries that have D1, D5, momentum and KK monopole charges. We show that there exists a method to embed these geometries into asymptotically- {AdS}_3× {S}^3/{{Z}}_N solutions, and hence to obtain infinite families of flows whose infrared is NHEK. This indicates that the CFT dual to the NHEK geometry is the IR fixed point of a Renormalization Group flow from a known local UV CFT and opens the door to its explicit construction.

  4. Twistor methods for AdS$_5$

    CERN Document Server

    Adamo, Tim; Williams, Jack

    2016-01-01

    We consider the application of twistor theory to five-dimensional anti-de Sitter space. The twistor space of AdS$_5$ is the same as the ambitwistor space of the four-dimensional conformal boundary; the geometry of this correspondence is reviewed for both the bulk and boundary. A Penrose transform allows us to describe free bulk fields, with or without mass, in terms of data on twistor space. Explicit representatives for the bulk-to-boundary propagators of scalars and spinors are constructed, along with twistor action functionals for the free theories. Evaluating these twistor actions on bulk-to-boundary propagators is shown to produce the correct two-point functions.

  5. Effects of ad placement and type on consumer responses to podcast ads.

    Science.gov (United States)

    Ritter, Eric A; Cho, Chang-Hoan

    2009-10-01

    The purpose of this study was to understand the effects of podcast ad placement and podcast ad type on consumers' perceived intrusiveness, perceived irritation, attitude toward the ad, and ad avoidance. Our 2 x 2 (traditional ad vs. sponsorship by beginning vs. middle) experimental study found that sponsorships generated better consumer responses than did traditional ads and that podcast ads placed at the beginning of audio podcasts yielded better consumer responses than those placed in the middle. Implications for marketers and advertisers are discussed. PMID:19817565

  6. Y-system for form factors at strong coupling in AdS5 and with multi-operator insertions in AdS3

    Science.gov (United States)

    Gao, Zhiquan; Yang, Gang

    2013-06-01

    We study form factors in {N}=4 SYM at strong coupling in general kinematics and with multi-operator insertions by using gauge/string duality and integrability techniques. This generalizes the AdS3 results of Maldacena and Zhiboedov in two non-trivial aspects. The first generalization to AdS5 space was motivated by its potential connection to strong coupling Higgs-to-three-gluons amplitudes in QCD which was observed recently at weak coupling. The second generalization to multi-operator insertions was motivated as a step towards applying on-shell techniques to compute correlation functions at strong coupling. In this picture, each operator is associated to a monodromy condition on the cusp solutions. We construct Y-systems for both cases. The Y -functions are related to the spacetime (cross) ratios. Their WKB approximations based on a rational function P ( z) are also studied. We focus on the short operators, while the prescription is hopefully also applicable for more general operators.

  7. The PredictAD project

    DEFF Research Database (Denmark)

    Antila, Kari; Lötjönen, Jyrki; Thurfjell, Lennart;

    2013-01-01

    Alzheimer's disease (AD) is the most common cause of dementia affecting 36 million people worldwide. As the demographic transition in the developed countries progresses towards older population, the worsening ratio of workers per retirees and the growing number of patients with age-related illnes...

  8. Stringy Membranes in AdS/CFT

    CERN Document Server

    Axenides, Minos; Linardopoulos, Georgios

    2013-01-01

    We study membrane configurations in AdS_{7/4}xS^{4/7}. The membranes are wrapped around the compact manifold S^{4/7} and are dynamically equivalent to bosonic strings in AdS_5. We thus conveniently identify them as "stringy membranes". For the case of AdS_7xS^4, their construction is carried out by embedding the Polyakov action for classical bosonic strings in AdS_5, into the corresponding membrane action. Therefore, every string configuration in AdS_5 can be realized by an appropriately chosen stringy membrane in AdS_7xS^4. We discuss the possibility of this being also the case for stringy membranes in AdS_4xS^7/Z^k (k > 1 or k = 1). By performing a stability analysis to the constructed solutions, we find that the (membrane) fluctuations along their transverse directions are organized in multiple Lam\\'{e} stability bands and gaps in the space of parameters of the configurations. In this membrane picture, strings exhibit a single band/gap structure. Since the spectrum of quadratic fluctuations is important fo...

  9. Writing CFT correlation functions as AdS scattering amplitudes

    CERN Document Server

    Penedones, Joao

    2010-01-01

    We explore the Mellin representation of conformal correlation functions recently proposed by Mack. Examples in the AdS/CFT context reinforce the analogy between Mellin amplitudes and scattering amplitudes. We conjecture a simple formula relating the bulk scattering amplitudes to the asymptotic behavior of Mellin amplitudes and show that previous results on the flat space limit of AdS follow from our new formula. We find that the Mellin amplitudes are particularly useful in the case of conformal gauge theories in the planar limit. In this case, the four point Mellin amplitudes are meromorphic functions whose poles and their residues are entirely determined by two and three point functions of single-trace operators. This makes the Mellin amplitudes the ideal objects to attempt the conformal bootstrap program in higher dimensions.

  10. Upregulated GABA inhibitory function in AD/HD children with Child Behavior Checklist–Dysregulation Profile: 123I-iomazenil SPECT study

    Directory of Open Access Journals (Sweden)

    Shinichiro eNagamitsu

    2015-06-01

    Full Text Available The Child Behavior Checklist–Dysregulation Profile (CBCL-DP refers to a pattern of elevated scores on the Attention Problems, Aggression, and Anxiety/Depression subscales of the Child Behavior Checklist. The aim of the present study was to investigate the potential role of GABA inhibitory neurons in children with attention deficit/hyperactivity disorder (AD/HD and dysregulation assessed with a dimensional measure. Brain single photon emission computed tomography (SPECT was performed in 35 children with AD/HD using 123I-iomazenil, which binds with high affinity to benzodiazepine receptors. Iomazenil binding activities were assessed with respect to the presence or absence of a threshold CBCL-DP (a score ≥210 for the sum of the three subscales Attention Problems, Aggression, and Anxiety/Depression. We then attempted to identify which CBCL-DP subscale explained the most variance with respect to SPECT data, using age, sex, and history of maltreatment as covariates. Significantly higher iomazenil binding activity was seen in the posterior cingulate cortex (PCC of AD/HD children with a significant CBCL-DP. The Anxiety/Depression subscale on the CBCL had significant effects on higher iomazenil binding activity in the left superior frontal, middle frontal, and temporal regions, as well as in the PCC. The present brain SPECT findings suggest that GABAergic inhibitory neurons may play an important role in the neurobiology of the CBCL-DP, in children with ADHD.

  11. Ultraviolet asymptotics and singular dynamics of AdS perturbations

    CERN Document Server

    Craps, Ben; Vanhoof, Joris

    2015-01-01

    Important insights into the dynamics of spherically symmetric AdS-scalar field perturbations can be obtained by considering a simplified time-averaged theory accurately describing perturbations of amplitude epsilon on time-scales of order 1/epsilon^2. The coefficients of the time-averaged equations are complicated expressions in terms of the AdS scalar field mode functions, which are in turn related to the Jacobi polynomials. We analyze the behavior of these coefficients for high frequency modes. The resulting asymptotics can be useful for understanding the properties of the finite-time singularity in solutions of the time-averaged theory recently reported in the literature. We highlight, in particular, the gauge dependence of this asymptotics, with respect to the two most commonly used gauges. The harsher growth of the coefficients at large frequencies in higher-dimensional AdS suggests strengthening of turbulent instabilities in higher dimensions. In the course of our derivations, we arrive at recursive rel...

  12. CO RELATIONAL STUDY ON HIGH SCHOOL MANAGERS

    OpenAIRE

    ANITA FATEMI REZVAN

    2012-01-01

    Aim. This paper examined the relationship between transformational leadership and life skills among high school managers in Iran.Background. Previous studies have found significant positive relationship between transformational leadership and life skills.Method. Acorrelation study was carried out with a randomly sample contained of 98 (52 males and 46 females) of high school managers. The participants responded to a Multifactor Leadership Questionnaire – MLQ (by Bass & Avolio d...

  13. Noncommutative extension of AdS–CFT and holographic superconductors

    International Nuclear Information System (INIS)

    In this Letter, we consider a Non-Commutative (NC) extension of AdS–CFT correspondence and its effects on holographic superconductors. NC corrections are incorporated via the NC generalization of Schwarzschild black hole metric in AdS with the probe limit. We study NC effects on the relations connecting the charge density and the critical temperature of the Holographic Superconductors. Furthermore, condensation operator of the superconductor has been analyzed. Our results suggest that generically, NC effects increase the critical temperature of the holographic superconductor

  14. Noncommutative extension of AdS-CFT and holographic superconductors

    Science.gov (United States)

    Pramanik, Souvik; Das, Sudipta; Ghosh, Subir

    2015-03-01

    In this Letter, we consider a Non-Commutative (NC) extension of AdS-CFT correspondence and its effects on holographic superconductors. NC corrections are incorporated via the NC generalization of Schwarzschild black hole metric in AdS with the probe limit. We study NC effects on the relations connecting the charge density and the critical temperature of the Holographic Superconductors. Furthermore, condensation operator of the superconductor has been analyzed. Our results suggest that generically, NC effects increase the critical temperature of the holographic superconductor.

  15. Noncommutative extension of AdS–CFT and holographic superconductors

    Directory of Open Access Journals (Sweden)

    Souvik Pramanik

    2015-03-01

    Full Text Available In this Letter, we consider a Non-Commutative (NC extension of AdS–CFT correspondence and its effects on holographic superconductors. NC corrections are incorporated via the NC generalization of Schwarzschild black hole metric in AdS with the probe limit. We study NC effects on the relations connecting the charge density and the critical temperature of the Holographic Superconductors. Furthermore, condensation operator of the superconductor has been analyzed. Our results suggest that generically, NC effects increase the critical temperature of the holographic superconductor.

  16. Noncommutative extension of AdS–CFT and holographic superconductors

    Energy Technology Data Exchange (ETDEWEB)

    Pramanik, Souvik, E-mail: souvick.in@gmail.com; Das, Sudipta, E-mail: sudipta_jumaths@yahoo.co.in; Ghosh, Subir, E-mail: subir_ghosh2@rediffmail.com

    2015-03-06

    In this Letter, we consider a Non-Commutative (NC) extension of AdS–CFT correspondence and its effects on holographic superconductors. NC corrections are incorporated via the NC generalization of Schwarzschild black hole metric in AdS with the probe limit. We study NC effects on the relations connecting the charge density and the critical temperature of the Holographic Superconductors. Furthermore, condensation operator of the superconductor has been analyzed. Our results suggest that generically, NC effects increase the critical temperature of the holographic superconductor.

  17. Impairment of blood brain barrier is related with the neuroinflammation induced peripheral immune status in intracerebroventricular colchicine injected rats: An experimental study with mannitol.

    Science.gov (United States)

    Sil, Susmita; Ghosh, Arijit; Ghosh, Tusharkanti

    2016-09-01

    The neurodegeneration in AD patients may be associated with changes of peripheral immune responses. Some peripheral immune responses are altered due to neuroinflammation in colchicine induced AD (cAD) rats. The leaky blood brain barrier (BBB) in cAD-rats may be involved in inducing peripheral inflammation, though there is no report in this regard. Therefore, the present study was designed to investigate the role of BBB in cADrats by altering the BBB in a time dependent manner with injection (i.v.) of mannitol (BBB opener). The inflammatory markers in the brain and serum along with the peripheral immune responses were measured after 30 and 60min of mannitol injection in cAD rats. The results showed higher inflammatory markers in the hippocampus and serum along with alterations in peripheral immune parameters in cAD rats. Although the hippocampal inflammatory markers did not further change after mannitol injection in cAD rats, the serum inflammatory markers and peripheral immune responses were altered and these changes were greater after 60min than that of 30min of mannitol injection. The present study shows that the peripheral immune responses in cAD rats after 30 and 60min of mannitol injection are related to magnitude of impairment of BBB in these conditions. It can be concluded from this study that impairment of BBB in cAD rats is related to the changes of peripheral immune responses observed in that condition.

  18. Impairment of blood brain barrier is related with the neuroinflammation induced peripheral immune status in intracerebroventricular colchicine injected rats: An experimental study with mannitol.

    Science.gov (United States)

    Sil, Susmita; Ghosh, Arijit; Ghosh, Tusharkanti

    2016-09-01

    The neurodegeneration in AD patients may be associated with changes of peripheral immune responses. Some peripheral immune responses are altered due to neuroinflammation in colchicine induced AD (cAD) rats. The leaky blood brain barrier (BBB) in cAD-rats may be involved in inducing peripheral inflammation, though there is no report in this regard. Therefore, the present study was designed to investigate the role of BBB in cADrats by altering the BBB in a time dependent manner with injection (i.v.) of mannitol (BBB opener). The inflammatory markers in the brain and serum along with the peripheral immune responses were measured after 30 and 60min of mannitol injection in cAD rats. The results showed higher inflammatory markers in the hippocampus and serum along with alterations in peripheral immune parameters in cAD rats. Although the hippocampal inflammatory markers did not further change after mannitol injection in cAD rats, the serum inflammatory markers and peripheral immune responses were altered and these changes were greater after 60min than that of 30min of mannitol injection. The present study shows that the peripheral immune responses in cAD rats after 30 and 60min of mannitol injection are related to magnitude of impairment of BBB in these conditions. It can be concluded from this study that impairment of BBB in cAD rats is related to the changes of peripheral immune responses observed in that condition. PMID:27288705

  19. A note about a pure spin-connection formulation of General Relativity and spin-2 duality in (A)dS

    CERN Document Server

    Basile, Thomas; Boulanger, Nicolas

    2015-01-01

    We investigate the problem of finding a pure spin-connection formulation of General Relativity with non-vanishing cosmological constant. We first revisit the problem at the linearised level and find that the pure spin-connection, quadratic Lagrangian, takes a form reminiscent to Weyl gravity, given by the square of a Weyl-like tensor. Upon Hodge dualisation, we show that the dual gauge field in (A)dS$_D$ transforms under $GL(D)$ in the same representation as a massive graviton in the flat spacetime of the same dimension. We give a detailed proof that the physical degrees of freedom indeed correspond to a massless graviton propagating around the (anti-) de Sitter background and finally speculate about a possible nonlinear pure-connection theory dual to General Relativity with cosmological constant.

  20. ADS National Programmes: Germany

    International Nuclear Information System (INIS)

    The German R&D programme for ADS development is related to the partitioning and transmutation of spent fuel. This programme is implemented mainly by the three national research centres belonging to the Helmholtz Association, i.e. Karlsruhe Institute of Technology (KIT), Forschungszentrum Jülich (FZJ) in cooperation with the Technical University of Aachen (RWTH Aachen) and the Helmholtz Zentrum Dresden Rossendorf (HZDR). The main purpose of this R&D programme is the prospect to manage the high level radioactive waste such as to reduce the burden on a final repository. P&T does not eliminate the need for a final repository whatever the strategy, but it allows the reduction of the radio-toxicity associated with radioactive waste, the increase of the repository capacity as a consequence of the reduction of masses to be stored and their associated residual heat load. Different fuel cycle scenarios to implement P&T can be envisaged. These scenarios have been evaluated to identify the impact of P&T on the characteristics, number and deployment pace of the installations of the fuel cycle (reprocessing, fuel fabrication, storage etc). Almost all activities conducted in the R&D programme are embedded in European and international projects and initiatives. In the following more details on the relevant components of the R&D programme are summarized

  1. ADS National Programmes: Russian Federation

    International Nuclear Information System (INIS)

    Studies on accelerator driven systems (ADS), which be used as burners of long lived radioactive waste accrued due to operation of thermal reactors, first of all, minor actinides (MA), are carried out in some Russian research institutes (ITEP, SSC RF - IPPE, VNIIEF, JINR, RSC KI, IYaI RAN, OKB ‘GIDROPRESS’, VNIITF etc.). These researches are mainly connected with studying physical processes existing in ADS and their parameters and with design studies and substantiation of experimental ADS facilities. One of the most important directions of researches is the acquirement of quite precise and reliable nuclear data on MA with reference to conditions existing in ADS. Now a coordinated programme of researches on measurement and estimation of nuclear data for 22 isotopes of U, Pu, Np, Am, Cm, Bk and Cf in neutron energy range from 0.05 eV up to 30 MeV has been prepared. Development of different variants of ADS has put a task of comparison of their efficiency as burners of MA

  2. Mobile ad hoc networking

    CERN Document Server

    John Wiley & Sons

    2004-01-01

    "Assimilating the most up-to-date information on research and development activities in this rapidly growing area, Mobile Ad Hoc Networking covers physical, data link, network, and transport layers, as well as application, security, simulation, and power management issues in sensor, local area, personal, and mobile ad hoc networks. Each of the book's sixteen chapters has been written by a top expert and discusses in-depth the most important topics in the field. Mobile Ad Hoc Networking is an excellent reference and guide for professionals seeking an in-depth examination of topics that also provides a comprehensive overview of the current state-of-the-art."--Jacket.

  3. A Study of the Value Added by Transformational Leadership Practices to Teachers' Job Satisfaction and Organizational Commitment

    Science.gov (United States)

    Kieres, Katherine H.

    2013-01-01

    Based on Bass and Riggio's (2006) Augmentation Model of Transactional and Transformational Leadership, this quantitative study sought to identify the amount of variance in teacher job satisfaction and organizational commitment that can be explained by principals' transformational leadership behaviors, above and beyond the influence of…

  4. A Study of the Value Added by Transformational Leadership Practices to Teachers' Job Satisfaction and Organizational Commitment

    Science.gov (United States)

    Kieres, Katherine H.; Gutmore, Daniel

    2014-01-01

    Based on Bass and Riggio's (2006) Augmentation Model of Transactional and Transformational Leadership, this quantitative study sought to identify the amount of variance in teacher job satisfaction and organizational commitment that can be explained by principals' transformational leadership behaviors, above and beyond the influence of…

  5. Developing School Evaluation Methods to Improve the Quality of Schooling in China: A Pilot "Value Added" Study

    Science.gov (United States)

    Peng, Wen Jung; Thomas, Sally M.; Yang, Xijie; Li, Jianzhong

    2006-01-01

    This article describes the background and findings of a research project on school effectiveness and evaluation in one regional education authority in China. The study was the outcome of a China/UK academic link aiming to improve research capacity and the evaluation of educational quality in China, funded by the British Council in Beijing, on…

  6. Alzheimer's disease - input of vitamin D with mEmantine assay (AD-IDEA trial: study protocol for a randomized controlled trial

    Directory of Open Access Journals (Sweden)

    Gautier Jennifer

    2011-10-01

    Full Text Available Abstract Background Current treatments for Alzheimer's disease and related disorders (ADRD are symptomatic and can only temporarily slow down ADRD. Future possibilities of care rely on multi-target drugs therapies that address simultaneously several pathophysiological processes leading to neurodegeneration. We hypothesized that the combination of memantine with vitamin D could be neuroprotective in ADRD, thereby limiting neuronal loss and cognitive decline. The aim of this trial is to compare the effect after 24 weeks of the oral intake of vitamin D3 (cholecalciferol with the effect of a placebo on the change of cognitive performance in patients suffering from moderate ADRD and receiving memantine. Methods The AD-IDEA Trial is a unicentre, double-blind, randomized, placebo-controlled, intent-to-treat, superiority trial. Patients aged 60 years and older presenting with moderate ADRD (i.e., Mini-Mental State Examination [MMSE] score between 10-20, hypovitaminosis D (i.e., serum 25-hydroxyvitamin D [25OHD] Discussion The combination of memantine plus vitamin D may represent a new multi-target therapeutic class for the treatment of ADRD. The AD-IDEA Trial seeks to provide evidence on its efficacy in limiting cognitive and functional declines in ADRD. Trial Registration ClinicalTrials.gov number, NCT01409694

  7. Strings in AdS3 and the SL(2,R) WZW Model. Part 1: The spectrum

    International Nuclear Information System (INIS)

    In this paper we study the spectrum of bosonic string theory on AdS3. We study classical solutions of the SL(2,R) WZW model, including solutions for long strings with non-zero winding number. We show that the model has a symmetry relating string configurations with different winding numbers. We then study the Hilbert space of the WZW model, including all states related by the above symmetry. This leads to a precise description of long strings. We prove a no-ghost theorem for all the representations that are involved and discuss the scattering of the long string

  8. The FORCE Fitness Profile--Adding a Measure of Health-Related Fitness to the Canadian Armed Forces Operational Fitness Evaluation.

    Science.gov (United States)

    Gagnon, Patrick; Spivock, Michael; Reilly, Tara; Mattie, Paige; Stockbrugger, Barry

    2015-11-01

    In 2013, the Canadian Armed Forces (CAF) implemented the Fitness for Operational Requirements of Canadian Armed Forces Employment (FORCE), a field expedient fitness test designed to predict the physical requirements of completing common military tasks. Given that attaining this minimal physical fitness standard may not represent a challenge to some personnel, a fitness incentive program was requested by the chain of command to recognize and reward fitness over and above the minimal standard. At the same time, it was determined that the CAF would benefit from a measure of general health-related fitness, in addition to this measure of operational fitness. The resulting incentive program structure is based on gender and 8 age categories. The results on the 4 elements of the FORCE evaluation were converted to a point scale from which normative scores were derived, where the median score corresponds to the bronze level, and silver, gold, and platinum correspond to a score which is 1, 2, and 3 SDs above this median, respectively. A suite of rewards including merit board point toward promotions and recognition on the uniform and material rewards was developed. A separate group rewards program was also tabled, to recognize achievements in fitness at the unit level. For general fitness, oxygen capacity was derived from FORCE evaluation results and combined with a measure of abdominal circumference. Fitness categories were determined based on relative risks of mortality and morbidity for each age and gender group. Pilot testing of this entire program was performed with 624 participants to assess participants' reactions to the enhanced test, and also to verify logistical aspects of the electronic data capture, calculation, and transfer system. The newly dubbed fitness profile program was subsequently approved by the senior leadership of the CAF and is scheduled to begin a phased implementation in June 2015. PMID:26506187

  9. The FORCE Fitness Profile--Adding a Measure of Health-Related Fitness to the Canadian Armed Forces Operational Fitness Evaluation.

    Science.gov (United States)

    Gagnon, Patrick; Spivock, Michael; Reilly, Tara; Mattie, Paige; Stockbrugger, Barry

    2015-11-01

    In 2013, the Canadian Armed Forces (CAF) implemented the Fitness for Operational Requirements of Canadian Armed Forces Employment (FORCE), a field expedient fitness test designed to predict the physical requirements of completing common military tasks. Given that attaining this minimal physical fitness standard may not represent a challenge to some personnel, a fitness incentive program was requested by the chain of command to recognize and reward fitness over and above the minimal standard. At the same time, it was determined that the CAF would benefit from a measure of general health-related fitness, in addition to this measure of operational fitness. The resulting incentive program structure is based on gender and 8 age categories. The results on the 4 elements of the FORCE evaluation were converted to a point scale from which normative scores were derived, where the median score corresponds to the bronze level, and silver, gold, and platinum correspond to a score which is 1, 2, and 3 SDs above this median, respectively. A suite of rewards including merit board point toward promotions and recognition on the uniform and material rewards was developed. A separate group rewards program was also tabled, to recognize achievements in fitness at the unit level. For general fitness, oxygen capacity was derived from FORCE evaluation results and combined with a measure of abdominal circumference. Fitness categories were determined based on relative risks of mortality and morbidity for each age and gender group. Pilot testing of this entire program was performed with 624 participants to assess participants' reactions to the enhanced test, and also to verify logistical aspects of the electronic data capture, calculation, and transfer system. The newly dubbed fitness profile program was subsequently approved by the senior leadership of the CAF and is scheduled to begin a phased implementation in June 2015.

  10. European project of PDS XADS: preliminary study of the XADS design; El proyecto europeo PDS Xads: Estudios prelimiares de diseno de un sistema accionado por acelerador (ADS)

    Energy Technology Data Exchange (ETDEWEB)

    Jardi, X.; Carluec, B.

    2003-07-01

    The demonstration of the practicability of transmutation on an industrial scale requires to perata at a industrialscale requires to operate at a European level, an experimental ADS (XADS) which will demonstrate the coupling of the accelerator, the neutron spallation target and the subcritical core. Complementary to the demonstration of the basic phenomena involved in the ADS technlogies, the preliminary engineering design studies of the XADS have to be performed in order to select the most promising technical concpets, to address the critical points of the whole system, to identify the research and development (R & D) in support, to define the safety and licensing issues, to preliminary assess the cost of the installation, and, then, to consolidate the roadmap of the XADS development. The assessment and comparison studies of the different concpetual designs of the main systems will allow to identify the most promising solutions which could be studied in detail in the next phases, and eventually realised. The PDS-XADS project is presented in this article. (Author)

  11. Calcium Chloride in Neonatal Parenteral Nutrition Solutions with and without Added Cysteine: Compatibility Studies Using Laser and Micro-Flow Imaging Methodology.

    Directory of Open Access Journals (Sweden)

    Robert K Huston

    Full Text Available Previous studies of compatibility of calcium chloride (CaCl2 and phosphates have not included particle counts in the range specified by the United States Pharmacopeia. Micro-flow imaging techniques have been shown to be comparable to light obscuration when determining particle count and size in pharmaceutical solutions.The purpose of this study was to do compatibility testing for parenteral nutrition (PN solutions containing CaCl2 using dynamic light scattering and micro-flow imaging techniques.Solutions containing TrophAmine (Braun Medical Inc, Irvine, CA, CaCl2, and sodium phosphate (NaPhos were compounded with and without cysteine. All solutions contained standard additives to neonatal PN solutions including dextrose, trace metals, and electrolytes. Control solutions contained no calcium or phosphate. Solutions were analyzed for particle size and particle count. Means of Z-average particle size and particle counts of controls were determined. Study solutions were compared to controls and United States Pharmacopeia (USP Chapter 788 guidelines. The maximum amount of Phos that was compatible in solutions that contained at least 10 mmol/L of Ca in 2.5% amino acids (AA was determined. Compatibility of these solutions was verified by performing analyses of 5 repeats of these solutions. Microscopic analyses of the repeats were also performed.Amounts of CaCl2 and NaPhos that were compatible in solutions containing 1.5%, 2%, 2.5%, and 3% AA were determined. The maximum amount of NaPhos that could be added to TrophAmine solutions of > = 2.5% AA containing at least 10 mmol/L of CaCl2 was 7.5 mmol/L. Adding 50 mg/dL of cysteine increased the amount of NaPhos that could be added to solutions containing 10 mmol/L of CaCl2 to 10 mmol/L.Calcium chloride can be added to neonatal PN solutions containing NaPhos in concentrations that can potentially provide an intravenous intake of adequate amounts of calcium and phosphorus.

  12. Euclidean Wilson loops and Minimal Area Surfaces in Minkowski AdS3

    CERN Document Server

    Irrgang, Andrew

    2015-01-01

    The AdS/CFT correspondence relates Wilson loops in N=4 SYM theory to minimal area surfaces in AdS5xS5 space. If the Wilson loop is Euclidean and confined to a plane (t,x) then the dual surface is Euclidean and lives in Minkowski AdS3. In this paper we study such minimal area surfaces generalizing previous results obtained in the Euclidean case. Since the surfaces we consider have the topology of a disk, the holonomy of the flat current vanishes which is equivalent to the condition that a certain boundary Schroedinger equation has all its solutions anti-periodic. If the potential for that Schroedinger equation is found then reconstructing the surface and finding the area become simpler. In particular we write a formula for the Area in terms of the Schwarzian derivative of the contour. Finally an infinite parameter family of analytical solutions using Riemann Theta functions is described. In this case, both the area and the shape of the surface are given analytically and used to check the previous results.

  13. The effect of adding group-based counselling to individual lifestyle counselling on changes in dietary intake. The Inter99 study - a randomized controlled trial

    DEFF Research Database (Denmark)

    Toft, Ulla; Kristoffersen, Lis; Ladelund, Steen;

    2008-01-01

    participants were invited for a health examination. High risk individuals were included in this study (n = 2 356) and changes in dietary intake were analyzed using multilevel linear regression analyses. RESULTS: At one-year follow-up group A had significantly increased the unsaturated/saturated fat ratio......ABSTRACT: BACKGROUND: Few studies have investigated the specific effect of single intervention components in randomized controlled trials. The purpose was to investigate the effect of adding group-based diet and exercise counselling to individual life-style counselling on long-term changes...... in dietary habits. METHODS: The study was a randomized controlled intervention study. From a general Danish population, aged 30 to 60 years (n = 61,301), two random sample were drawn (group A, n = 11,708; group B, n = 1,308). Subjects were invited for a health screening program. Participation rate was 52...

  14. Self-Dual Warped AdS$_3$ Black Holes

    CERN Document Server

    Chen, Bin; Ning, Bo

    2010-01-01

    We propose a new class of solutions of three-dimensional topological massive gravity. These solutions are non-extremal black holes, with their extremal counterparts being discrete quotients of spacelike warped AdS$_3$ along the $U(1)_L$ isometry. We study the thermodynamics of these black holes and show that the first law is satisfied. We also show that for consistent boundary conditions, the asymptotic symmetry generators form only one copy of the Virasoro algebra with central charge $c_L = \\frac{4\

  15. PASS2 database for the structure-based sequence alignment of distantly related SCOP domain superfamilies: update to version 5 and added features.

    Science.gov (United States)

    Gandhimathi, Arumugam; Ghosh, Pritha; Hariharaputran, Sridhar; Mathew, Oommen K; Sowdhamini, R

    2016-01-01

    Structure-based sequence alignment is an essential step in assessing and analysing the relationship of distantly related proteins. PASS2 is a database that records such alignments for protein domain superfamilies and has been constantly updated periodically. This update of the PASS2 version, named as PASS2.5, directly corresponds to the SCOPe 2.04 release. All SCOPe structural domains that share less than 40% sequence identity, as defined by the ASTRAL compendium of protein structures, are included. The current version includes 1977 superfamilies and has been assembled utilizing the structure-based sequence alignment protocol. Such an alignment is obtained initially through MATT, followed by a refinement through the COMPARER program. The JOY program has been used for structural annotations of such alignments. In this update, we have automated the protocol and focused on inclusion of new features such as mapping of GO terms, absolutely conserved residues among the domains in a superfamily and inclusion of PDBs, that are absent in SCOPe 2.04, using the HMM profiles from the alignments of the superfamily members and are provided as a separate list. We have also implemented a more user-friendly manner of data presentation and options for downloading more features. PASS2.5 version is available at http://caps.ncbs.res.in/pass2/. PMID:26553811

  16. Results from Ad Hoc and Routinely Collected Data among Celiac Women with Infertility or Pregnancy Related Disorders: Italy, 2001–2011

    OpenAIRE

    Francesca Fortunato; Domenico Martinelli; Rosa Prato; Biagio Pedalino

    2014-01-01

    Celiac disease (CD) is a chronic autoimmune illness triggered by gluten consumption in genetically predisposed individuals. Worldwide, CD prevalence is approximately 1%. Several studies suggest a higher prevalence of undiagnosed CD in patients with infertility. We described reproductive disorders and assessed the frequency of hospital admissions for infertility among celiac women aged 15–49. We conducted two surveys enrolling a convenient sample of celiac women, residing in Apulia or in Basil...

  17. The effect of umeclidinium added to inhaled corticosteroid/long-acting β2-agonist in patients with symptomatic COPD: a randomised, double-blind, parallel-group study.

    Science.gov (United States)

    Sousa, Ana R; Riley, John H; Church, Alison; Zhu, Chang-Qing; Punekar, Yogesh S; Fahy, William A

    2016-01-01

    Benefits of triple therapy with a long-acting muscarinic antagonist (LAMA), added to inhaled corticosteroid (ICS)/long-acting β2-agonist (LABA), have been demonstrated. Limited data assessing the efficacy of the LAMA umeclidinium (UMEC) added to ICS/LABA are available. The aim of this study is to evaluate the efficacy and safety of UMEC added to ICS/LABAs in patients with moderate-to-very-severe COPD. This is a multicentre, randomised, double-blind, parallel-group study. Patients were symptomatic (modified Medical Research Council Dyspnoea Scale score ⩾2), despite receiving ICS/LABA (fluticasone propionate/salmeterol (FP/SAL, branded) 500/50 mcg, budesonide/formoterol (BD/FOR, branded) 200/6 mcg or 400/12 mcg, or other ICS/LABAs) ⩾30 days before the run-in (7±2 days). Patients were randomised 1:1 to once-daily UMEC 62.5 mcg or placebo (PBO), added to twice-daily open-label ICS/LABA for 12 weeks. Primary end point was trough forced expiratory volume in 1 s (FEV1) at Day 85; secondary end point was weighted mean (WM) 0-6 h FEV1 at Day 84; other end points included COPD Assessment Test (CAT) score and Transition Dyspnoea Index (TDI) score. Adverse events (AEs) were investigated. In the UMEC+ICS/LABA and PBO+ICS/LABA groups, 119 and 117 patients were randomised, respectively. Patients received FP/SAL (40%), BD/FOR (43%) and other ICS/LABAs (17%). UMEC+ICS/LABA resulted in significant improvements in trough FEV1 (Day 85) and in WM 0-6 h FEV1 (Day 84) versus PBO+ICS/LABA (difference: 123 and 148 ml, respectively, both P<0.001). Change from baseline for UMEC+ICS/LABA versus PBO+ICS/LABA was significantly different for CAT score at Day 84 (-1.31, P<0.05), but not for TDI score (0.40, P=0.152). AE incidence was similar with UMEC+ICS/LABA (38%) and PBO+ICS/LABA (42%). UMEC+ICS/LABA improved lung function and CAT score in patients with symptomatic COPD versus PBO+ICS/LABA (ClinicalTrials.gov NCT02257372). PMID:27334739

  18. AdS_3: the NHEK generation

    CERN Document Server

    Bena, Iosif; Puhm, Andrea

    2015-01-01

    It was argued in arXiv:1203.4227 that the five-dimensional near-horizon extremal Kerr (NHEK) geometry can be embedded in String Theory as the infrared region of an infinite family of non-supersymmetric geometries that have D1, D5, momentum and KK monopole charges. We show that there exists a method to embed these geometries into asymptotically-AdS_3 x S^3/Z_N solutions, and hence to obtain infinite families of flows whose infrared is NHEK. This indicates that the CFT dual to the NHEK geometry is the IR fixed point of a Renormalization Group flow from a known local UV CFT and opens the door to its explicit construction.

  19. 资源受限的Ad hoc网络中节点协作激励机制研究%Study on nodes cooperation incentive mechanism for Ad hoc network with resources constraint

    Institute of Scientific and Technical Information of China (English)

    李瑾; 刘玉清; 袁红

    2014-01-01

    Aiming at the selfishness of nodes in mobile Ad hoc network , a node status based incentive mechanism ( NSIM ) is proposed in this paper . Virtual money is used to motivate the nodes forwarding data . The node designs prices taking into account the nodes′ status to avoid nodes with limited resources participating in forwarding data . A safety module encryption mechanism is imported into the mechanism to prevent some nodes from tampering other nodes′ quoted price and illegitimately increasing its own virtual money . Simulation results show that NSIM mechanism can decrease the delivery delay and increase the delivery ratio .%针对移动 Ad hoc 网络中节点自私性问题,提出了一种基于节点状态的节点协作激励机制NSIM。利用虚拟货币来激励中间节点转发数据,节点的报价是综合考虑节点状态计算得出的,避免资源紧张的节点参与数据转发;在节点中引入安全模块和加密机制,防止节点篡改其他节点的报价和非法增加虚拟货币。仿真实验表明, NSIM 机制减小了时延,提高了分组投递率。

  20. Study on Remote Data Acquisition & Preprocessing Based on Ad hoc and Lab VIEW%基于Ad hoc和Lab VIEW的远程数据采集及预处理的研究

    Institute of Scientific and Technical Information of China (English)

    王建芳; 李伟华

    2008-01-01

    针对基于Ad hoe无线网络环境下的远程自动测试智能信息处理系统的多扰动、紧耦合的特点,提出了在Ad hoc网络环境下基于Lab VIEW 提取多传感器特征参数并进行预处理的技术,实现了实时动态的监测、数据的存储、远程通信和回放显示;采用Lab VIEW和网络传输技术,实现了远程测试系统的数据采集和预处理平台的开发;实测结果分析表明,经过数据采集及预处理后,降低了冗余数据量,提高了网络资源利用率,减少了系统开发成本.

  1. Does adding intraperitoneal paclitaxel to standard intraperitoneal regimen yield incremental survival? A propensity score-matched cohort study

    Institute of Scientific and Technical Information of China (English)

    YenHou Chang; ChienHsing Lu; MingShyen Yen; WaiHou Lee; Yi Chang; WeiPin Chang; and ChiMu Chuang

    2016-01-01

    We recruited consecutive patients with stage III epithelial ovarian, tubal, and peritoneal cancers who had optimal residual tumor after primary cytoreductive surgery and who received intraperitoneal chemotherapy between 2002 and 2012. Two propensity score‑matched sample cohorts were created. We found that the addition of paclitaxel as a second intraperitoneal agent on a 3‑week dosing schedule did not yield significant incremental survival benefits over the intraperitoneal delivery of a single cisplatin‑based regimen. If our findings could be confirmed by a prospective randomized study, then it would be interesting to explore the efcacy of shifting back to a dose‑dense intraperitoneal delivery of paclitaxel or a dose‑dense delivery of a new formulation of paclitaxel for the patients with stage III epithe‑lial ovarian, tubal, and peritoneal cancers.

  2. Feasibility of azacitidine added to standard chemotherapy in older patients with acute myeloid leukemia--a randomised SAL pilot study.

    Directory of Open Access Journals (Sweden)

    Utz Krug

    Full Text Available INTRODUCTION: Older patients with acute myeloid leukemia (AML experience short survival despite intensive chemotherapy. Azacitidine has promising activity in patients with low proliferating AML. The aim of this dose-finding part of this trial was to evaluate feasibility and safety of azacitidine combined with a cytarabine- and daunorubicin-based chemotherapy in older patients with AML. TRIAL DESIGN: Prospective, randomised, open, phase II trial with parallel group design and fixed sample size. PATIENTS AND METHODS: Patients aged 61 years or older, with untreated acute myeloid leukemia with a leukocyte count of <20,000/µl at the time of study entry and adequate organ function were eligible. Patients were randomised to receive azacitidine either 37.5 (dose level 1 or 75 mg/sqm (dose level 2 for five days before each cycle of induction (7+3 cytarabine plus daunorubicine and consolidation (intermediate-dose cytarabine therapy. Dose-limiting toxicity was the primary endpoint. RESULTS: Six patients each were randomised into each dose level and evaluable for analysis. No dose-limiting toxicity occurred in either dose level. Nine serious adverse events occurred in five patients (three in the 37.5 mg, two in the 75 mg arm with two fatal outcomes. Two patients at the 37.5 mg/sqm dose level and four patients at the 75 mg/sqm level achieved a complete remission after induction therapy. Median overall survival was 266 days and median event-free survival 215 days after a median follow up of 616 days. CONCLUSIONS: The combination of azacitidine 75 mg/sqm with standard induction therapy is feasible in older patients with AML and was selected as an investigational arm in the randomised controlled part of this phase-II study, which is currently halted due to an increased cardiac toxicity observed in the experimental arm. TRIAL REGISTRATION: This trial is registered at clinical trials.gov (identifier: NCT00915252.

  3. Value adding management: A concept and a case

    DEFF Research Database (Denmark)

    Jensen, Per Anker; Katchamart, Akarapong

    2012-01-01

    Purpose: To develop a management concept that can assist facilities managers in implementing value adding strategies and practices. The FM Value Map has been developed to analyse and demonstrate the different ways FM can add value. However, there is a need to develop management tools that can...... be used more directly and proactively by facilities managers to implement adding value strategies and practices. Methodology: The development of the concept of Value Adding Management is based on the management model for FM included in the European FM standards, recent theories on added value of FM...... and real estate and the related concept of Value Management from building projects. The chapter outlines a preliminary theoretical based management concept, which is investigated, tested and discussed based on a case study of LEGO. Findings: The case study provides a clear example of a company that actual...

  4. A study of the changes and continuities in ceramic production processes through the Bagaces period (300-800 AD) and early Sapoa period (800-1350 AD) on the southwest slopes of Volcan Rincon de la Vieja, Guanacaste

    International Nuclear Information System (INIS)

    The ways in which human societies have manufactured the ceramics have been studied at a time when lived major social changes in the Gran Nicoya. Aspects relating to the environment, the basic characterization of the investigated sites and background are treated to introduce the reader to the area of research. Field work associated with the recognition, realization of flat surfaces collections and excavations have been executed in the months of June of the year 2011, September to December 2011 and from February to April of the year 2012. The washing and drying of ceramic and lithic to be entered in a data base physical material was done following the excavation process. Specific techniques in specialized laboratories have been practiced to discuss the origins of the clay used in pottery production and the relationship to the social processes of the moment

  5. A Study of Process Dissociation of the Memory Effects of Sexual Appeal Printed AD%平面性诉求广告记忆效果的加工分离研究

    Institute of Scientific and Technical Information of China (English)

    彭彦琴

    2011-01-01

    With the increasingly fierce market competition,marketeers resort all the more to sexual appeal AD to attract consumers,increase consumer interest,and improve the advertisement effect.Therefore,an appropriate degree of sexual appeal and an analysis of advertisement audience cognitive information processing by sexual appeal are important.With the proliferation of advertising messages,advertisers are increasingly using sex appeal to attract the audiences attention.Despite a number of relevant studies at home and abroad, no agreement has been reached in terms of sexual appeal AD or the celebrity effect. Past studies used two methods to study the effects of advertising memory:direct measurement(e.g.recall,recognition) and implicit attitude.In fact,neither of the methods can distinguish between explicit and implicit memory.In the research of sexual appeal AD,most of the experimental results are from America,and local experiments are relatively few.So we need a new method and perspective for the study.In order to improve the memory effect of sexual appeal AD,analyzing the audience information processing sexual appeal AD is particularly important.Thus,this research used the PDP method to distinguish between the implicit and explicit information processing of audience to sexual appeal AD,to explore the information processing model and to explore the causes.In the study, 122 college students were chosen as testees.The study involved a 3×2×2 factorial experiment to investigate how cognitive information processing would respond to sexual appeal AD by analyzing the response to the bare type(implicative,generally,explicit) and different types of celebrity spokespersons(famous,ordinary ) in advertising. The results showed that 1.From the explicit control of processing,memory of implicative sexual appeal AD got the best effect.2. From the implicit automation processing,the automatic processing of explicit sexual appeal AD got the best effect.People paid more

  6. Quantum cat map dynamics on AdS$_2$

    CERN Document Server

    Axenides, Minos; Nicolis, Stam

    2016-01-01

    We present a toy model for the chaotic unitary scattering of single particle wave packets on the radial AdS$_2$ geometry of extremal BH horizons. Based on our recent work for the discretization of the AdS$_2$ space-time, which describes a finite and random geometry, by modular arithmetic, we investigate the validity of the eigenstate thermalization hypothesis (ETH), as well as that of the fast scrambling time bound conjecture (STB), for an observer with time evolution operator the quantum Arnol'd cat map (QACM). We find that the QACM, while possessing a linear spectrum, has eigenstates, which can be expressed in closed form, are found to be random and to satisfy the assumptions of the ETH.The implications are that the dynamics is described by a chaotic, unitary, single particle S-matrix, which completely delocalizes and randomizes initial gaussian wave packets . Applying results obtained by Dyson and Falk for the periods of the Arnol'd Cat Map(ACM),which are related to its mixing time, we also find that the t...

  7. Food branding influences ad libitum intake differently in children depending on weight status. Results of a pilot study.

    Science.gov (United States)

    Forman, Jamie; Halford, Jason C G; Summe, Heather; MacDougall, Megan; Keller, Kathleen L

    2009-08-01

    Environmental changes have facilitated the rapid increase in childhood obesity. One such change is increased presence of food marketing which promotes intake of high-fat, energy-dense foods. This study tested the hypotheses that overweight (OW) children are more sensitive to the intake-enhancing effects of food branding than non-OW children, and that the relationship between weight status and intake of branded foods is mediated by level of food brand awareness. Forty-three non-OW (n = 23) and OW (n = 20) children from diverse ethnic backgrounds participated in four dinnertime visits to test their intake of meals where food brands were present ("branded") or absent ("unbranded"). Food brand awareness was assessed by testing children's abilities to match food brand logos with correct foods and name specific brands from recall. Weight and height were measured on the first visit to determine BMI z-score and weight status. OW children consumed significantly more energy per meal than non-OW. Child age and brand awareness were positively associated. OW children consumed an additional 40 kcal in branded vs. unbranded meals whereas non-OW children consumed 45 kcal less in branded meals. Overweight children showed greater responsiveness to food branding, and they may be at risk in environments that are highly inundated with messages about food.

  8. Sensitivity and Specificity of the Screen for Child Anxiety Related Emotional Disorders (SCARED): A Community-Based Study

    Science.gov (United States)

    DeSousa, Diogo Araujo; Salum, Giovanni Abrahao; Isolan, Luciano Rassier; Manfro, Gisele Gus

    2013-01-01

    The aim of this cross-sectional community-based study was to examine the sensitivity and specificity of the Screen for Child Anxiety Related Emotional Disorders (SCARED) to the diagnosis of anxiety disorders (AD). Participants were 119 students aged 9-18. Psychiatric diagnoses were assessed by a psychiatrist throughout a structural clinical…

  9. On circular strings in (AdS3 × S 3)ϰ

    Science.gov (United States)

    Banerjee, Aritra; Panigrahi, Kamal L.

    2016-09-01

    The so called one-parameter (often called ϰ) deformed AdS string sigma models have attracted a lot of attention lately in the study of integrability in string theory. We construct various circular string solutions in the (AdS3 × S 3) ϰ background and describe the characteristics of such solutions qualitatively. We study the Bohr-Sommerfeld like quantization for these string states to characterise the motion. Further we find a `long' string limit of such circular strings in the ϰ-deformed AdS3 and find a novel dependence of the oscillation number on the energy in the next to leading order expansion.

  10. On circular strings in $(AdS_3 \\times S^3)_{\\varkappa}$

    CERN Document Server

    Banerjee, Aritra

    2016-01-01

    The so called one-parameter (often called $\\varkappa$) deformed $AdS$ string sigma models have attracted a lot of attention lately in the study of integrability in string theory. We construct various circular string solutions in the $(AdS_3 \\times S^3)_{\\varkappa}$ background and describe the characteristics of such solutions qualitatively. We study the Bohr-Sommerfeld like quantization for these string states to characterise the motion. Further we find a `long' string limit of such circular strings in the $\\varkappa$-deformed $AdS_3$ and find a novel dependence of the oscillation number on the energy in the next to leading order expansion.

  11. Belarus activity in ADS field

    International Nuclear Information System (INIS)

    Conclusions: • The YALINA facility is a unique installation which was designed as a zero power model of real ADS. • It is intended to study neutronics and kinetics of the sub-critical reactors driven by external neutron sources. • The successful operation of this facility is a scientific contribution from the Republic of Belarus, as well as the international team from EC and USA. • The experimental data are used to benchmark and validate methods and computer codes for designing and licensing ADS

  12. Self-Regulation of Emotion, Functional Impairment, and Comorbidity among Children with AD/HD

    Science.gov (United States)

    Anastopoulos, Arthur D.; Smith, Taylor F.; Garrett, Melanie E.; Morrissey-Kane, Erin; Schatz, Nicole K.; Sommer, Jennifer L.; Kollins, Scott H.; Ashley-Koch, Allison

    2011-01-01

    Objective: This study investigated the role of self-regulation of emotion in relation to functional impairment and comorbidity among children with and without AD/HD. Method: A total of 358 probands and their siblings participated in the study, with 74% of the sample participants affected by AD/HD. Parent-rated levels of emotional lability served…

  13. Online Ad Slotting With Cancellations

    CERN Document Server

    Constantin, Florin; Muthukrishnan, S; Pal, Martin

    2008-01-01

    Many advertisers buy advertisements (ads) on the Internet or on traditional media and seek simple, online mechanisms to reserve ad slots in advance. Media publishers represent a vast and varying inventory, and they too seek automatic, online mechanisms for pricing and allocating such reservations. In this paper, we present and study a simple model for auctioning such ad slots in advance. Bidders arrive sequentially and report which slots they are interested in. The seller must decide immediately whether or not to grant a reservation. Our model allows a seller to accept reservations, but possibly cancel the allocations later and pay the bidder a cancellation compensation (bump payment). Our main result is an online mechanism to derive prices and bump payments that is efficient to implement. This mechanism has many desirable properties. It is individually rational; winners have an incentive to be honest and bidding one's true value dominates any lower bid. Our mechanism's efficiency is within a constant fractio...

  14. Results from Ad Hoc and Routinely Collected Data among Celiac Women with Infertility or Pregnancy Related Disorders: Italy, 2001–2011

    Science.gov (United States)

    2014-01-01

    Celiac disease (CD) is a chronic autoimmune illness triggered by gluten consumption in genetically predisposed individuals. Worldwide, CD prevalence is approximately 1%. Several studies suggest a higher prevalence of undiagnosed CD in patients with infertility. We described reproductive disorders and assessed the frequency of hospital admissions for infertility among celiac women aged 15–49. We conducted two surveys enrolling a convenient sample of celiac women, residing in Apulia or in Basilicata (Italy). Moreover, we selected hospital discharge records (HDRs) of celiac women and women with an exemption for CD, and matched the lists with HDRs for reproductive disorders. In the surveys we included 91 celiac women; 61.5% of them reported menstrual cycle disorders. 47/91 reported at least one pregnancy and 70.2% of them reported problems during pregnancy. From the HDRs and the registry of exemption, we selected 4,070 women with CD; the proportion of women hospitalized for infertility was higher among celiac women than among resident women in childbearing age (1.2% versus 0.2%). Our findings highlight a higher prevalence of reproductive disorders among celiac women than in the general population suggesting that clinicians might consider testing for CD women presenting with pregnancy disorders or infertility. PMID:24895657

  15. Results from ad hoc and routinely collected data among celiac women with infertility or pregnancy related disorders: Italy, 2001-2011.

    Science.gov (United States)

    Fortunato, Francesca; Martinelli, Domenico; Prato, Rosa; Pedalino, Biagio

    2014-01-01

    Celiac disease (CD) is a chronic autoimmune illness triggered by gluten consumption in genetically predisposed individuals. Worldwide, CD prevalence is approximately 1%. Several studies suggest a higher prevalence of undiagnosed CD in patients with infertility. We described reproductive disorders and assessed the frequency of hospital admissions for infertility among celiac women aged 15-49. We conducted two surveys enrolling a convenient sample of celiac women, residing in Apulia or in Basilicata (Italy). Moreover, we selected hospital discharge records (HDRs) of celiac women and women with an exemption for CD, and matched the lists with HDRs for reproductive disorders. In the surveys we included 91 celiac women; 61.5% of them reported menstrual cycle disorders. 47/91 reported at least one pregnancy and 70.2% of them reported problems during pregnancy. From the HDRs and the registry of exemption, we selected 4,070 women with CD; the proportion of women hospitalized for infertility was higher among celiac women than among resident women in childbearing age (1.2% versus 0.2%). Our findings highlight a higher prevalence of reproductive disorders among celiac women than in the general population suggesting that clinicians might consider testing for CD women presenting with pregnancy disorders or infertility. PMID:24895657

  16. Results from Ad Hoc and Routinely Collected Data among Celiac Women with Infertility or Pregnancy Related Disorders: Italy, 2001–2011

    Directory of Open Access Journals (Sweden)

    Francesca Fortunato

    2014-01-01

    Full Text Available Celiac disease (CD is a chronic autoimmune illness triggered by gluten consumption in genetically predisposed individuals. Worldwide, CD prevalence is approximately 1%. Several studies suggest a higher prevalence of undiagnosed CD in patients with infertility. We described reproductive disorders and assessed the frequency of hospital admissions for infertility among celiac women aged 15–49. We conducted two surveys enrolling a convenient sample of celiac women, residing in Apulia or in Basilicata (Italy. Moreover, we selected hospital discharge records (HDRs of celiac women and women with an exemption for CD, and matched the lists with HDRs for reproductive disorders. In the surveys we included 91 celiac women; 61.5% of them reported menstrual cycle disorders. 47/91 reported at least one pregnancy and 70.2% of them reported problems during pregnancy. From the HDRs and the registry of exemption, we selected 4,070 women with CD; the proportion of women hospitalized for infertility was higher among celiac women than among resident women in childbearing age (1.2% versus 0.2%. Our findings highlight a higher prevalence of reproductive disorders among celiac women than in the general population suggesting that clinicians might consider testing for CD women presenting with pregnancy disorders or infertility.

  17. THE DISCUSSION OF NOUN COMPLEMENTS WITH NO SUFFIXES AND THE RELATION BETWEEN WORD CLASSES AND PHRASES TAKISIZ AD TAMLAMASI TARTIŞMASI VE TÜR – ÖBEK İLİŞKİSİ

    Directory of Open Access Journals (Sweden)

    Caner KERİMOĞLU

    2011-01-01

    Full Text Available The discussion of compound nouns with no suffixes has an important place in Turkish grammar writing. Recently, it is seen that this discussion has come to an end and the constructions like tahta kaşık “wooden spoon”, altın kolye “golden necklace” are accepted as adjective complements. In this study, firstly these discussions are evaluated and then the roles of word classes in phrases are discussed with regard to nouns and adjectives. Takısız ad tamlaması tartışması Türkçe dil bilgisi yazımında önemli bir yere sahiptir. Son yıllarda bu konuyla ilgili tartışmaların azaldığı ve akademik yayınların çoğunda tahta kaşık, altın kolye dizilişindeki yapıların sıfat tamlaması kabul edildiği görülmektedir. Bu çalışmada takısız ad tamlaması tartışmaları değerlendirildikten sonra, kelime türlerinin öbek kurmadaki rolleri sıfat ve ad türleri temelinde tartışılmaktadır.

  18. A Comparative Study of Relational and Non-Relational Database Models in a Web- Based Application

    OpenAIRE

    Cornelia Gyorödi; Robert Gyorödi; Roxana Sotoc

    2015-01-01

    The purpose of this paper is to present a comparative study between relational and non-relational database models in a web-based application, by executing various operations on both relational and on non-relational databases thus highlighting the results obtained during performance comparison tests. The study was based on the implementation of a web-based application for population records. For the non-relational database, we used MongoDB and for the relational database, we used MSSQL 2014. W...

  19. A comparative study of descriptions and value added of bibliographic records through MARC, DC and MODS: From the viewpoints of the users

    Directory of Open Access Journals (Sweden)

    Huei-Chu Chang

    2014-04-01

    Full Text Available The purpose of this study is to understand which bibliographic data are the core elements of the user’s queries? What users’ viewpoints about resource descriptions using different metadata standards? What kinds of value-added items are the users’ favorite when they conduct a bibliographic search? What are users’ viewpoints about bibliographic records integrated with the Digital Archival and Institutional Repository resources through metadata interoperability methods? This research adopted experiments, observation and interviews. The sample subjects are drawn from 14 students of The Graduate Institute of Library and Information Science and College of Agriculture and Natural Resources. First of all, the researcher displayed the bibliographic records using original MARC from the library. Secondly, users compared the images of OPAC from the library with the format of DC and MODS transformed through the MarcEdit software. Additionally, the researcher conducted interviews to understand users’ viewpoints about using three metadata schemas to describe the same book. Finally, the researcher asked the degree of users’ satisfaction about using bibliographic records alone and bibliographic records integrated with the Digital Archival and Institutional Repository resources. The findings suggest that libraries could provide more value-added and comprehensive services of bibliographic records and information retrieval, in order for all kinds of resources to be fully utilized, which helps to meet the users’ information needs.

  20. Content and Epistemic Relations: A Developmental Study of Recall

    Directory of Open Access Journals (Sweden)

    Sara Verbrugge

    2012-09-01

    Full Text Available The study investigates the types of coherence relations adults and children can recall after having read a text. We discerned content and epistemic relations (Dancygier, 1998; Sweetser, 1990. Content relations express relations between events in reality. Epistemic relations typically express relations between states of thinking (premise-conclusion relations. The relations between the two parts of a content or epistemic relation is often made explicit by means of connectives. The differences between these types of sentences have been shown in different areas (e.g., reasoning, clause integration, acquisition. However, no clear results could be reached as for recall of these relations and the interaction with connectives. We aim to clarify this debate by means of an experiment involving 539 participants. The experiment revealed that the difficulty associated with epistemic relations decreases as participants get older. Interestingly, connectives play a larger role in participants' ability to recall epistemic compared to content relations.

  1. Light-cone AdS/CFT-adapted approach to AdS fields/currents, shadows, and conformal fields

    CERN Document Server

    Metsaev, R R

    2015-01-01

    Light-cone gauge formulation of fields in AdS space and conformal field theory in flat space adapted for the study of AdS/CFT correspondence is developed. Arbitrary spin mixed-symmetry fields in AdS space and arbitrary spin mixed-symmetry currents, shadows, and conformal fields in flat space are considered on an equal footing. For the massless and massive fields in AdS and the conformal fields in flat space, simple light-cone gauge actions leading to decoupled equations of motion are found. For the currents and shadows, simple expressions for all 2-point functions are also found. We demonstrate that representation of conformal algebra generators on space of currents, shadows, and conformal fields can be built in terms of spin operators entering the light-cone gauge formulation of AdS fields. This considerably simplifies the study of AdS/CFT correspondence. Light-cone gauge actions for totally symmetric arbitrary spin long conformal fields in flat space are presented. We apply our approach to the study of tota...

  2. On shape dependence of holographic entanglement entropy in AdS4/CFT3

    CERN Document Server

    Fonda, Piermarco; Tonni, Erik

    2015-01-01

    We study the finite term of the holographic entanglement entropy of finite domains with smooth shapes and for four dimensional gravitational backgrounds. Analytic expressions depending on the unit vectors normal to the minimal area surface are obtained for both stationary and time dependent spacetimes. The special cases of AdS4, asymptotically AdS4 black holes, domain wall geometries and Vaidya-AdS backgrounds have been analysed explicitly. When the bulk spacetime is AdS4, the finite term is the Willmore energy of the minimal area surface viewed as a submanifold of the three dimensional flat Euclidean space. For the static spacetimes, some numerical checks involving spatial regions delimited by ellipses and non convex domains have been performed. In the case of AdS4, the infinite wedge has been also considered, recovering the known analytic formula for the coefficient of the logarithmic divergence.

  3. Dynamic ad hoc networks

    CERN Document Server

    Rashvand, Habib

    2013-01-01

    Motivated by the exciting new application paradigm of using amalgamated technologies of the Internet and wireless, the next generation communication networks (also called 'ubiquitous', 'complex' and 'unstructured' networking) are changing the way we develop and apply our future systems and services at home and on local, national and global scales. Whatever the interconnection - a WiMAX enabled networked mobile vehicle, MEMS or nanotechnology enabled distributed sensor systems, Vehicular Ad hoc Networking (VANET) or Mobile Ad hoc Networking (MANET) - all can be classified under new networking s

  4. Eating ad Libitum

    DEFF Research Database (Denmark)

    Hillersdal, Line

    in the context of the 'ad libitum meal'. The analytical interest is thus what kind of eaters and bodies are enacted in the meal test and what ideas of prevention and treatment are embedded in their standards. Drawing from ongoing empirical work among Danish obesity researchers performing scientific meal tests I...... ask what make up food stuff and eaters in the meal tests? More specifically I explore a scientific testing of changes in taste preferences before and after weight-loss surgery using an ad libitum buffet with a selection of different foods and another testing the effect of exercise on appetite also...

  5. A Comparative Study of Relational and Non-Relational Database Models in a Web- Based Application

    Directory of Open Access Journals (Sweden)

    Cornelia Gyorödi

    2015-11-01

    Full Text Available The purpose of this paper is to present a comparative study between relational and non-relational database models in a web-based application, by executing various operations on both relational and on non-relational databases thus highlighting the results obtained during performance comparison tests. The study was based on the implementation of a web-based application for population records. For the non-relational database, we used MongoDB and for the relational database, we used MSSQL 2014. We will also present the advantages of using a non-relational database compared to a relational database integrated in a web-based application, which needs to manipulate a big amount of data.

  6. Gender-Specific Neuroimmunoendocrine Response to Treadmill Exercise in 3xTg-AD Mice

    OpenAIRE

    Lydia Giménez-Llort; Yoelvis García; Karla Buccieri; Susana Revilla; Cristina Suñol; Rosa Cristofol; Coral Sanfeliu

    2010-01-01

    The 3xTg-AD mouse develops a progressive Alzheimer's disease- (AD-) like brain pathology that causes cognitive- and neuropsychiatric-like symptoms of dementia. Since its neuroimmunoendocrine axis is likewise impaired, this mouse is also useful for modelling complex age-related neurodegeneration. This study analyzed behavioral, physiological, neurochemical, pathological and immunoendocrine alterations in male and female 3xTg-AD mice and assayed the effects of a short therapy of forced physical...

  7. First principle study of magnetic and electronic properties of single X (X = Al, Si) atom added to small carbon clusters (C n X, n = 2-10)

    Science.gov (United States)

    Afshar, M.; Hoseini, S. S.; Sargolzaei, M.

    2016-07-01

    In this paper, the magnetic and electronic properties of single aluminum and silicon atom added to small carbon clusters (C n X; X = Al, Si; n = 2-10) are studied in the framework of generalized-gradient approximation using density functional theory. The calculations were performed for linear, two dimensional and three dimensional clusters based on full-potential local-orbital (FPLO) method. The total energies, HOMO-LUMO energy gap and total magnetic moments of the most stable structures are presented in this work. The calculations show that C n Si clusters have more stability compared to C n Al clusters. In addition, our magnetic calculations were shown that the C n Al isomers are magnetic objects whereas C n Si clusters are nonmagnetic objects.

  8. Teacher Leader Human Relations Skills: A Comparative Study

    Science.gov (United States)

    Roby, Douglas E.

    2012-01-01

    In this study, 142 graduate school teachers working in schools throughout southwestern Ohio assessed their human relation skills. A human relations survey was used for the study, and results were compared with colleagues assessing the teachers in the study. The survey was developed using a Likert-type scale, and was based on key elements affecting…

  9. Detecting Precontact Anthropogenic Microtopographic Features in a Forested Landscape with Lidar: A Case Study from the Upper Great Lakes Region, AD 1000-1600.

    Science.gov (United States)

    Howey, Meghan C L; Sullivan, Franklin B; Tallant, Jason; Kopple, Robert Vande; Palace, Michael W

    2016-01-01

    Forested settings present challenges for understanding the full extent of past human landscape modifications. Field-based archaeological reconnaissance in forests is low-efficiency and most remote sensing techniques are of limited utility, and together, this means many past sites and features in forests are unknown. Archaeologists have increasingly used light detection and ranging (lidar), a remote sensing tool that uses pulses of light to measure reflecting surfaces at high spatial resolution, to address these limitations. Archaeology studies using lidar have made significant progress identifying permanent structures built by large-scale complex agriculturalist societies. Largely unaccounted for, however, are numerous small and more practical modifications of landscapes by smaller-scale societies. Here we show these may also be detectable with lidar by identifying remnants of food storage pits (cache pits) created by mobile hunter-gatherers in the upper Great Lakes during Late Precontact (ca. AD 1000-1600) that now only exist as subtle microtopographic features. Years of intensive field survey identified 69 cache pit groups between two inland lakes in northern Michigan, almost all of which were located within ~500 m of a lakeshore. Applying a novel series of image processing techniques and statistical analyses to a high spatial resolution DTM we created from commercial-grade lidar, our detection routine identified 139 high potential cache pit clusters. These included most of the previously known clusters as well as several unknown clusters located >1500 m from either lakeshore, much further from lakeshores than all previously identified cultural sites. Food storage is understood to have emerged regionally as a risk-buffering strategy after AD 1000 but our results indicate the current record of hunter-gatherer cache pit food storage is markedly incomplete and this practice and its associated impact on the landscape may be greater than anticipated. Our study also

  10. Detecting Precontact Anthropogenic Microtopographic Features in a Forested Landscape with Lidar: A Case Study from the Upper Great Lakes Region, AD 1000-1600.

    Science.gov (United States)

    Howey, Meghan C L; Sullivan, Franklin B; Tallant, Jason; Kopple, Robert Vande; Palace, Michael W

    2016-01-01

    Forested settings present challenges for understanding the full extent of past human landscape modifications. Field-based archaeological reconnaissance in forests is low-efficiency and most remote sensing techniques are of limited utility, and together, this means many past sites and features in forests are unknown. Archaeologists have increasingly used light detection and ranging (lidar), a remote sensing tool that uses pulses of light to measure reflecting surfaces at high spatial resolution, to address these limitations. Archaeology studies using lidar have made significant progress identifying permanent structures built by large-scale complex agriculturalist societies. Largely unaccounted for, however, are numerous small and more practical modifications of landscapes by smaller-scale societies. Here we show these may also be detectable with lidar by identifying remnants of food storage pits (cache pits) created by mobile hunter-gatherers in the upper Great Lakes during Late Precontact (ca. AD 1000-1600) that now only exist as subtle microtopographic features. Years of intensive field survey identified 69 cache pit groups between two inland lakes in northern Michigan, almost all of which were located within ~500 m of a lakeshore. Applying a novel series of image processing techniques and statistical analyses to a high spatial resolution DTM we created from commercial-grade lidar, our detection routine identified 139 high potential cache pit clusters. These included most of the previously known clusters as well as several unknown clusters located >1500 m from either lakeshore, much further from lakeshores than all previously identified cultural sites. Food storage is understood to have emerged regionally as a risk-buffering strategy after AD 1000 but our results indicate the current record of hunter-gatherer cache pit food storage is markedly incomplete and this practice and its associated impact on the landscape may be greater than anticipated. Our study also

  11. Added fructose: a principal driver of type 2 diabetes mellitus and its consequences.

    Science.gov (United States)

    DiNicolantonio, James J; O'Keefe, James H; Lucan, Sean C

    2015-03-01

    Data from animal experiments and human studies implicate added sugars (eg, sucrose and high-fructose corn syrup) in the development of diabetes mellitus and related metabolic derangements that raise cardiovascular (CV) risk. Added fructose in particular (eg, as a constituent of added sucrose or as the main component of high-fructose sweeteners) may pose the greatest problem for incident diabetes, diabetes-related metabolic abnormalities, and CV risk. Conversely, whole foods that contain fructose (eg, fruits and vegetables) pose no problem for health and are likely protective against diabetes and adverse CV outcomes. Several dietary guidelines appropriately recommend consuming whole foods over foods with added sugars, but some (eg, recommendations from the American Diabetes Association) do not recommend restricting fructose-containing added sugars to any specific level. Other guidelines (such as from the Institute of Medicine) allow up to 25% of calories as fructose-containing added sugars. Intake of added fructose at such high levels would undoubtedly worsen rates of diabetes and its complications. There is no need for added fructose or any added sugars in the diet; reducing intake to 5% of total calories (the level now suggested by the World Health Organization) has been shown to improve glucose tolerance in humans and decrease the prevalence of diabetes and the metabolic derangements that often precede and accompany it. Reducing the intake of added sugars could translate to reduced diabetes-related morbidity and premature mortality for populations. PMID:25639270

  12. Stable Isotope (delta OXYGEN-18, Delta Deuterium, Delta CARBON-13) Dendroclimatological Studies in the Waterloo Region of Southern Ontario, Canada, Between AD 1610 and 1990.

    Science.gov (United States)

    Buhay, William Mark

    Oxygen (delta^{18} O), hydrogen (delta^2H) and carbon (delta^{13}C) isotopes were measured in wood cellulose from elm, white pine and maple trees that grew in southwestern Ontario, Canada. The measured oxygen and hydrogen isotopic data were used for model-based reconstructions of delta^{18}{O}_{meteoric water}, mean annual temperature (MAT) and relative humidity for a period, AD 1610 to 1880, that precedes instrumental records of climate. The carbon isotope measurements were compared with the Cellulose Model inferred climate data to reveal additional environmental information. Modifications made to the Cellulose Model focused on the dynamics of oxygen and hydrogen isotopic fractionation in plants during evapotranspiration and photosynthetic assimilation. For instance, kinetic fractionation of ^{18}O was found to be predictable from theoretical considerations of leaf energy balance and boundary layer dynamics. Kinetic fractionation during evapotranspiration is sensitive to the nature of the boundary layer, which is controlled by leaf size and morphology. Generally, plants with small segmented leaves have a lower component of turbidity in the leaf boundary layer, which results in higher kinetic fractionation values, than do plants having large simple leaves and more turbulent boundary layers. Kinetic ^2H enrichment in plant leaf water can also be rationalized in terms of leaf size and morphology when an apparent temperature-dependent isotope effect, acting in opposition to evaporative enrichment, is taken into account. Accounting for this temperature -dependent isotope effect helps to: (1) reconcile hydrogen kinetic fractionation inconsistencies for different leaves; (2) explain a temperature effect previously attributed to variable biochemical fractionation during cellulose synthesis, and; (3) verify hydrogen biochemical effects in plants. This improved characterization of the oxygen and hydrogen isotopic effects in plants, using the modified Cellulose Model, helped

  13. The Tetrahedron Zamolodchikov Algebra and the AdS5 x S5 S-matrix

    CERN Document Server

    Mitev, Vladimir; Tsuboi, Zengo

    2012-01-01

    The S-matrix of the AdS5 x S5 string theory is a tensor product of two centrally extended su(2|2) S-matrices, each of which is related to the R-matrix of the Hubbard model. The R-matrix of the Hubbard model was first found by Shastry, who ingeniously exploited the fact that, for zero coupling, the Hubbard model can be decomposed into two XX models. In this article, we review and clarify this construction from the AdS/CFT perspective and investigate the implications this has for the AdS5 x S5 S-matrix.

  14. Holographic properties in three-dimensional AdS soliton using $AdS_3/CFT_2$

    CERN Document Server

    Peng, Yan

    2016-01-01

    We study the holographic description of a superconductor by the $AdS_{3}/CFT_{2}$ correspondence. The system is constructed with a Maxwell field and a charged scalar field coupled in the (2+1)-dimensional AdS soliton background. With analytical methods, we obtain the exact expression for the critical chemical potential as $\\mu_{c} = 1 + \\sqrt{1+m^2}$, which has also been generalized to higher dimensions as $\\mu_c \\thickapprox a + \\sqrt{m^2-m_{BF}^2}$ in this work. Around the phase transition points, we find a correspondence between the value of the scalar field at the tip and the scalar operator at infinity. We also arrive at the classical second order phase transition threshold exponent $\\beta=\\frac{1}{2}$ as the same as the mean field theory near the critical chemical potential. As the condensation becomes heavier, we show surprisingly that superconducting phases exist only in a certain range of the chemical potential, which is very different from higher-dimensional cases. And for the small enough negative ...

  15. Clinical study on IgG4-related autoimmune pancreatitis

    Institute of Scientific and Technical Information of China (English)

    吴庆军

    2013-01-01

    Objective To investigate the clinical features of IgG4-related autoimmune pancreatitis(IgG4-related AIP). Methods A prospective cohort study on IgG4 related disease(IgG4-RD) was carried out in Peking Union Medical College Hospital during December 2010 to June

  16. Experimental and numerical study on the flow pattern of the ADS windowless spallation target with a second free surface downstream using model fluid water

    Energy Technology Data Exchange (ETDEWEB)

    Xiong, Zhenqin, E-mail: zqxiong@sjtu.edu.cn; Gu, Hanyang; Gong, Shenjie

    2015-09-15

    Highlights: • A windowless spallation target with a buffer tank is tested. • Shape of the main free surface is recorded. • Streamline is obtained with the planar laser induced fluorescence method. • Stability of free surface is improved by the buffer tank. • Flow structure is simulated using RNG k-e turbulence model and VOF model. - Abstract: The windowless spallation targets are a promising design solution for accelerator driven system (ADS) due to their extended life compared to the spallation targets with a window. Keeping the stability of the free surface and reducing the recirculation zone is one of the key tasks for the design of a windowless spallation target. A windowless spallation target with a second free surface downstream (which is a buffer used to stabilize the main free surface of the flow) is studied experimentally and numerically using water at atmospheric pressure. By using planar laser induced fluorescence technique (LIF), the flow pattern inside the target zone is visualized for Reynolds numbers varying between 3.5 × 10{sup 4} and 7.0 × 10{sup 4} and pressure differences from 100 to 804 Pa. The experimental results reveal that the stability of the free surface is improved by adding a buffer in the downstream thus making it easier to control the height of the surface. The effect of the pressure difference between the void above the second free surface (high pressure side) and beam pipe (low pressure side) on the flow pattern is analyzed, as well as the inlet flow rate. The height of the surface length decreases with an increase in the pressure difference. The formation of the spallation zone is simulated with Fluent using the LES turbulence model and VOF model. The interface predicted agrees well with the experimental results.

  17. Experimental and numerical study on the flow pattern of the ADS windowless spallation target with a second free surface downstream using model fluid water

    International Nuclear Information System (INIS)

    Highlights: • A windowless spallation target with a buffer tank is tested. • Shape of the main free surface is recorded. • Streamline is obtained with the planar laser induced fluorescence method. • Stability of free surface is improved by the buffer tank. • Flow structure is simulated using RNG k-e turbulence model and VOF model. - Abstract: The windowless spallation targets are a promising design solution for accelerator driven system (ADS) due to their extended life compared to the spallation targets with a window. Keeping the stability of the free surface and reducing the recirculation zone is one of the key tasks for the design of a windowless spallation target. A windowless spallation target with a second free surface downstream (which is a buffer used to stabilize the main free surface of the flow) is studied experimentally and numerically using water at atmospheric pressure. By using planar laser induced fluorescence technique (LIF), the flow pattern inside the target zone is visualized for Reynolds numbers varying between 3.5 × 104 and 7.0 × 104 and pressure differences from 100 to 804 Pa. The experimental results reveal that the stability of the free surface is improved by adding a buffer in the downstream thus making it easier to control the height of the surface. The effect of the pressure difference between the void above the second free surface (high pressure side) and beam pipe (low pressure side) on the flow pattern is analyzed, as well as the inlet flow rate. The height of the surface length decreases with an increase in the pressure difference. The formation of the spallation zone is simulated with Fluent using the LES turbulence model and VOF model. The interface predicted agrees well with the experimental results

  18. Multi-spike strings in AdS3 with mixed three-form fluxes

    Science.gov (United States)

    Banerjee, Aritra; Sadhukhan, Abhishake

    2016-05-01

    The string sigma model in AdS3 × S 3 supported by mixed three-form fluxes has recently been proved to be integrable which led to a plethora of work in this background including proposals for S matrix and study of semiclassical string profiles. Motivated by this, in this paper, we present a study of `spiky' strings in this background. We analyze the string profiles in detail and also find the dispersion relation between the charges in the `long' string limit after solving the equations of motion perturbatively upto the leading order in the Neveu-Schwarz flux b. We find that the dispersion for 2 spikes gets corrected by the term -b^2/2 log S. We also discuss the fate of the solution in the limit of pure NS-NS flux.

  19. The progress of researches on ADS in China

    International Nuclear Information System (INIS)

    The conceptual study of Accelerator Driven System (ADS) had lasted for about five years and ended in 1999 in China. As one project of 'the major state basic research program (973)' in energy domain, which is sponsored by the China Ministry of Science and Technology (MOST), a five years program of basic research for ADS physics and related technology has been launched since 2000. CIAE (China Institute of Atomic Energy), IHEP (Institute of High Energy Physics), PKU-IHIP (Institute of Heavy Ion Physics in Peking University) and other institutions are jointly carrying on the research. The research activities are focused on HPPA physics and technology, reactor physics of external source driven sub-critical assembly, nuclear data base and material study. For HPPA, a high current injector consisting of an ECR ion source, LEBT and a RFQ accelerating structure of 3MeV will be built. In reactor physics study, a series of neutron multiplication experimental study has been carried out and is being carrying on. The VENUS facility will be constructed as the basic experimental platform for the neutronic study in ADS blanket. It's a zero power sub-critical neutron multiplying assembly driven by external 14MeV neutron produced by a pulsed neutron genreator. The theoretical, experimental and simulation study on nuclear data, material properties and nuclear fuel circulation related to ADS is carrying on to provide the database for ADS system analysis. the experimental high current beam injector consisted of ECR ion source, low energy beam transport system and RFQ type acceleration structure. The injector is one of the most important part of the medium energy high power proton accelerator and of worldwide interest in this community. The main results on ADS related researches and primary physical consideration of this verification system--the Venus program will be reported. (authors)

  20. The summary of researches on ADS in China

    Institute of Scientific and Technical Information of China (English)

    XIA Haihong; CUI Baoqun; ZHAO Zhixiang; LI Jigen; SHI Yongqian; HAN Yinlu; ZHU Shengyun; XU Yongli; GUAN Xialing; FU Shinian

    2007-01-01

    The conceptual study on the accelerator driven system (ADS) that lasted for about five years ended in 1999 in China. As one project of the National Basic Research Program of China (973 Program) in the energy domain, which is sponsored by the China Ministry of Science and Technology (MOST), a five-year-program of fundamental research of ADS physics and related technology was launched in 2000 and passed national review at the end of 2005. The China Institute of Atomic Energy (CIAE), the Institute of High Energy Physics (IHEP), the Institute of Heavy Ion Physics in Peking University (PKU-IHIP) and other institutions jointly carried out the research. The research activities were focused on HPPA physics and technology, reactor physics of external source driven sub-critical assembly, nuclear data base and material study. For HPPA, a high current injector consisting of an ECR ion source, LEBT and an RFQ accelerating structure of 3.5 MeV was built. In reactor physics study, a series of neutron multiplication experimental study has been carded out and still being done. The VENUS facility has been constructed as the basic experimental platform for neutronics study in ADS blanket. It's a zero power sub-critical neutron multiplying assembly driven by external neutron produced by a pulsed neutron generator. The theoretical, experimental and simulation study on nuclear data, matcrial properties and nuclear fuel circulation related to ADS is carrying on to provide the database for ADS system analysis. The main results on ADS related researches will be reported.

  1. Management job ads

    DEFF Research Database (Denmark)

    Holmgreen, Lise-Lotte

    2014-01-01

    The article asks whether it is not the responsibility of corporations to address the issue of women being underrepresented in Danish management jobs. In other words, it is argued that corporations should be encouraged to engage more actively in the recruitment of both men and women for management...... jobs by discursively constructing job ads that appeal to both sexes. This argument is part of the broader field of corporate social responsibility, corporate citizenship, and stakeholder management, which involves discussions of the obligations of corporations to acknowledge and mitigate...... the increasingly widespread impact that their activities have on communities and social structures. The article emphasises the need for more active engagement on the part of corporations by analysing the discursive construction of preferred candidates in a small sample of Danish management job ads. By means...

  2. Adding more value to added-value

    DEFF Research Database (Denmark)

    Marian, Livia

    Recent studies reveal that consumers respond favourably to “organic plus” products with additional ethical attributes. The aim of the current study is to explore whether consumers would notice and value further improvements in the animal welfare standards than those imposed by the organic...

  3. Adding linear orders

    CERN Document Server

    Shelah, Saharon

    2011-01-01

    We address the following question: Can we expand an NIP theory by adding a linear order such that the expansion is still NIP? Easily, if acl(A)=A for all A, then this is true. Otherwise, we give counterexamples. More precisely, there is a totally categorical theory for which every expansion by a linear order has IP. There is also an \\omega-stable NDOP theory for which every expansion by a linear order interprets bounded arithmetic.

  4. On Information Loss in AdS$_3$/CFT$_2$

    CERN Document Server

    Fitzpatrick, A Liam; Li, Daliang; Wang, Junpu

    2016-01-01

    We discuss information loss from black hole physics in AdS$_3$, focusing on two sharp signatures infecting CFT$_2$ correlators at large central charge $c$: 'forbidden singularities' arising from Euclidean-time periodicity due to the effective Hawking temperature, and late-time exponential decay in the Lorentzian region. We study an infinite class of examples where forbidden singularities can be resolved by non-perturbative effects at finite $c$, and we show that the resolution has certain universal features that also apply in the general case. Analytically continuing to the Lorentzian regime, we find that the non-perturbative effects that resolve forbidden singularities qualitatively change the behavior of correlators at times $t \\sim S_{BH}$, the black hole entropy. This may resolve the exponential decay of correlators at late times in black hole backgrounds. By Borel resumming the $1/c$ expansion of exact examples, we explicitly identify 'information-restoring' effects from heavy states that should correspo...

  5. An Investigation of AdS2 Backreaction and Holography

    CERN Document Server

    Engelsöy, Julius; Verlinde, Herman

    2016-01-01

    We investigate a dilaton gravity model in AdS2 proposed by Almheiri and Polchinski and develop an 1D effective description in terms of a dynamical boundary time with a Schwarzian derivative action. We show that the effective model is equivalent to a 1D version of Liouville theory, and investigate its dynamics and symmetries via a standard canonical framework. We include the coupling to arbitrary conformal matter and analyze the effective action in the presence of possible sources. We compute commutators of local operators at large time separation, and match the result with the time shift due to a gravitational shockwave interaction. We study a black hole evaporation process and comment on the role of entropy in this model.

  6. An investigation of AdS2 backreaction and holography

    Science.gov (United States)

    Engelsöy, Julius; Mertens, Thomas G.; Verlinde, Herman

    2016-07-01

    We investigate a dilaton gravity model in AdS2 proposed by Almheiri and Polchinski [1] and develop a 1d effective description in terms of a dynamical boundary time with a Schwarzian derivative action. We show that the effective model is equivalent to a 1d version of Liouville theory, and investigate its dynamics and symmetries via a standard canonical framework. We include the coupling to arbitrary conformal matter and analyze the effective action in the presence of possible sources. We compute commutators of local operators at large time separation, and match the result with the time shift due to a gravitational shockwave interaction. We study a black hole evaporation process and comment on the role of entropy in this model.

  7. Functional foods for added value

    OpenAIRE

    Mark-Herbert, Cecilia

    2002-01-01

    In this study innovation involves the development of a new product category; i.e. new products, new processes and new business. The development process is conveyed in narratives where a radically new product group, functional foods, is developed. These high-tech food products are associated with added value for the food business as well as for individuals and society at large. In the past decades Swedish food companies have faced an increasing competition. With increased competitive pressures...

  8. AdS 3-manifolds and Higgs bundles

    DEFF Research Database (Denmark)

    Alessandrini, Daniele; Li, Qiongling

    2015-01-01

    In this paper we investigate the relationships between closed AdS 3-manifolds and Higgs bundles. We have a new way to construct AdS structures that allows us to see many of their properties explicitly, for example we can recover the very recent formula by Tholozan for the volumes. We also find...

  9. Value-Added Business Based On Small Scale Of Fisheries A Case Study On Nortern And Shouthern Coasts Of Java Lamongan And Pelabuhanratu Regency Indonesia

    Directory of Open Access Journals (Sweden)

    Budi Wardono

    2015-08-01

    Full Text Available The development of fisheries sector is intended to improve the role of creating a strong linkage with other sectors by increasing the value added absorbing labor forces and increasing peoples income so that this can make the economy grow well. The value added is a value that increases due to a commodity that has been processed transported or stored in a production. Lamongan and Pelabuhanratu regencies are one of fisheries centers on the north and the south coast of Java Island. The aim of this research was to know the value added and the business margin of fisheries from the processing and marketing aspects. The research was carried out in two locations Northern coast Lamongan regencies and Shouther coasts Pelabuhanratu regencies Indoneisa. The data used were primary data the people involved in the business including fishing marketing and processing product. The results showed that the process of fisheries product yielded the value added and margin that were created from the incorporation of business benefit added input contribution other input and direct reward for the labor forces. The value added and the business margin of product processing can reach 2 to 3 fold from the main input value. The value added and the business margin of fisheries product processing were very big. This was the source of economy growth there. The effort to develop the business of fisheries product processing in the small scale need to be supported with various programs especially in the market access and funding.

  10. Gauge Symmetries and Holographic Anomalies of Chern-Simons and Transgression AdS Gravity

    CERN Document Server

    Mora, Pablo

    2014-01-01

    We review the issue of gauge and gravitational anomalies with backgrounds, maybe offering a new outlook on some aspects of these questions. We compute the holographic anomalies of hypothetical theories dual, in the sense of the AdS-CFT correspondence, to Chern-Simons AdS gravities. Those anomalies are either gauge anomalies associated to the AdS gauge group of the theory or diffeomorphism anomalies, with each kind related to the other. As a result of using suitable action principles por Chern-Simons AdS gravities, coming from Transgression forms, we obtain finite results without the need for further regularization. Our results are of potential interest for Lovelock gravity theories, as it has been shown that the boundary terms dictated by the transgressions for Chern-Simons gravities are also suitable to regularize Lovelock theories. The Wess-Zumino consistency condition ensures that anomalies of the generic form computed here should appear for these and other theories.

  11. AdS5×S(5) mirror model as a string sigma model.

    Science.gov (United States)

    Arutyunov, Gleb; van Tongeren, Stijn J

    2014-12-31

    Doing a double Wick rotation in the world sheet theory of the light cone AdS5×S(5) superstring results in an inequivalent, so-called mirror theory that plays a central role in the field of integrability in the AdS-CFT correspondence. We show that this mirror theory can be interpreted as the light cone theory of a free string on a different background. This background is related to dS5×H(5) by a double T-duality, and has hidden supersymmetry. The geometry can also be extracted from an integrable deformation of the AdS5×S(5) sigma model, and we prove the observed mirror duality of these deformed models at the bosonic level as a byproduct. While we focus on AdS5×S(5), our results apply more generally.

  12. Motion of particles on a Four-Dimensional Asymptotically AdS Black Hole with Scalar Hair

    CERN Document Server

    Gonzalez, P A; Vasquez, Yerko

    2015-01-01

    Motivated by black hole solutions with matter fields outside their horizon, we study the effect of these matter fields in the motion of massless and massive particles. We consider as background a four-dimensional asymptotically AdS black hole with scalar hair. The geodesics are studied numerically and we discuss about the differences in the motion of particles between the four-dimensional asymptotically AdS black holes with scalar hair and their no-hair limit, that is, Schwarzschild AdS black holes. Mainly, we found that there are bounded orbits like planetary orbits in this background. However, the periods associated to circular orbits are modified by the presence of the scalar hair. Besides, we found that some classical tests such as perihelion precession, deflection of light and gravitational time delay have the standard value of general relativity plus a correction term coming from the cosmological constant and the scalar hair. Finally, we found a specific value of the parameter associated to the scalar h...

  13. Motion of particles on a four-dimensional asymptotically AdS black hole with scalar hair

    Energy Technology Data Exchange (ETDEWEB)

    Gonzalez, P.A.; Olivares, Marco [Universidad Diego Portales, Facultad de Ingenieria, Santiago (Chile); Vasquez, Yerko [Universidad de La Serena, Departamento de Fisica, Facultad de Ciencias, La Serena (Chile)

    2015-10-15

    Motivated by black hole solutions with matter fields outside their horizon, we study the effect of these matter fields on the motion of massless and massive particles. We consider as background a four-dimensional asymptotically AdS black hole with scalar hair. The geodesics are studied numerically and we discuss the differences in the motion of particles between the four-dimensional asymptotically AdS black holes with scalar hair and their no-hair limit, that is, Schwarzschild AdS black holes. Mainly, we found that there are bounded orbits like planetary orbits in this background. However, the periods associated to circular orbits are modified by the presence of the scalar hair. Besides, we found that some classical tests such as perihelion precession, deflection of light, and gravitational time delay have the standard value of general relativity plus a correction term coming from the cosmological constant and the scalar hair. Finally, we found a specific value of the parameter associated to the scalar hair, in order to explain the discrepancy between the theory and the observations, for the perihelion precession of Mercury and light deflection. (orig.)

  14. Half BPS states in AdS_5 x Y^{p,q}

    CERN Document Server

    Gava, Edi; Milanesi, Giuseppe; O'Loughlin, Martin

    2008-01-01

    We study a class of solutions of IIB Supergravity which are asymptotically AdS_5 x Y^{p,q}. They have an R x SO(4) x SU(2) x U(1) isometry and preserve half of the 8 supercharges of the background geometry. They are described by a set of second order differential equations that we have found and analysed in a previous paper, where we studied 1/8 BPS states in the maximally supersymmetric AdS_5 x S^5 background. These geometries correspond to certain chiral primary operators of the N=1 superconformal quiver theories, dual to IIB theory on AdS_5 x Y^{p,q}. We also show how to recover the AdS_5 x Y^{p,q} backgrounds by suitably doubling the number of preserved supersymmetries. We then solve the differential equations perturbatively in a large AdS_5 radius expansion, imposing asymptotic AdS_5 x Y^{p,q} boundary conditions. We compute the global baryonic and mesonic charges, including the R-charge. As for the computation of the mass, i.e. the conformal dimension D of the dual field theory operators, which is notor...

  15. Evaporation of large black holes in AdS

    International Nuclear Information System (INIS)

    The AdS/CFT correspondence offers a new perspective on the long-standing black hole information paradox. However, to be able to use the available gauge/gravity machinery one is forced to consider so-called 'large' black holes in AdS, and these objects are thermodynamically stable - they do not evaporate. We describe a simple toy model that allows large AdS black holes to decay, by coupling the emitted radiation to an external scalar field propagating in an auxiliary space. This effectively changes the properties of the boundary of AdS, making it partly absorbing. We demonstrate that the evaporation process never ceases by explicitly presenting (a) the transmission coefficient for a wave scattering from the bulk into auxiliary space and (b) the greybody factor for a black 3-brane in an AdS background. Therefore, the model provides an interesting framework to address the information paradox using AdS/CFT techniques.

  16. Study of Mothers' Anxieties Related to Their Children's Future

    Science.gov (United States)

    Ilgar, Sengul

    2015-01-01

    The purpose of this study is to study anxieties of mothers related to their children's future. Qualitative method was used in order to study anxieties of mothers from different socio-economic levels. Sample of the study participants are 129 mothers living in Istanbul. 32 of those mothers are from upper socio-economic level, 57, from middle…

  17. Generalizations of Lunin-Maldacena transformation on the $AdS sub 5 x S sup 5$ background

    OpenAIRE

    Rashkov, R. C.; Viswanathan, K. S.; Yang, Yi

    2005-01-01

    In this paper we consider a simple generalization of the method of Lunin and Maldacena for generating new string backgrounds based on TsT-transformations. We study multi-shift $Ts... sT$ transformations applied to backgrounds with at least two U(1) isometries. We prove that the string currents in any two backgrounds related by Ts...sT-transformations are equal. Applying this procedure to the $AdS_{5}\\times S^{5}$, we find a new background and study some properties of the semiclassical strings.

  18. Generalization of the Lunin-Maldacena transformation on the AdS5xS5 background

    International Nuclear Information System (INIS)

    In this paper we consider a simple generalization of the method of Lunin and Maldacena for generating new string backgrounds based on TsT transformations. We study multishift Ts···sT transformations applied to backgrounds with at least two U(1) isometries. We prove that the string currents in any two backgrounds related by Ts···sT transformations are equal. Applying this procedure to the AdS5xS5, we find a new background and study some properties of the semiclassical strings

  19. Phase transition and thermodynamical geometry for Schwarzschild AdS black hole in $AdS_5\\times{S^5}$ spacetime

    OpenAIRE

    Zhang, Jia-Lin; Cai, Rong-Gen; Yu, Hongwei

    2014-01-01

    We study the thermodynamics and thermodynamic geometry of a five-dimensional Schwarzschild AdS black hole in AdS 5 × S 5 spacetime by treating the cosmological constant as the number of colors in the boundary gauge theory and its conjugate quantity as the associated chemical potential. It is found that the chemical potential is always negative in the stable branch of black hole thermodynamics and it has a chance to be positive, but appears in the unstable branch. We calculate the scalar curva...

  20. Introduction to AdS-CFT

    CERN Document Server

    Nastase, Horatiu

    2007-01-01

    These lectures present an introduction to AdS-CFT, and are intended both for begining and more advanced graduate students, which are familiar with quantum field theory and have a working knowledge of their basic methods. Familiarity with supersymmetry, general relativity and string theory is helpful, but not necessary, as the course intends to be as self-contained as possible. I will introduce the needed elements of field and gauge theory, general relativity, supersymmetry, supergravity, strings and conformal field theory. Then I describe the basic AdS-CFT scenario, of ${\\cal N}=4 $ Super Yang-Mills's relation to string theory in $AdS_5\\times S_5$, and applications that can be derived from it: 3-point functions, quark-antiquark potential, finite temperature and scattering processes, the pp wave correspondence and spin chains. I also describe some general properties of gravity duals of gauge theories.

  1. Holographic Description of AdS Cosmologies

    CERN Document Server

    Hertog, T; Hertog, Thomas; Horowitz, Gary T.

    2005-01-01

    To gain insight in the quantum nature of the big bang, we study the dual field theory description of asymptotically anti-de Sitter solutions of supergravity that have cosmological singularities. The dual theories do not appear to have a stable ground state. One regularization of the theory causes the cosmological singularities in the bulk to turn into giant black holes with scalar hair. We interpret these hairy black holes in the dual field theory and use them to compute a finite temperature effective potential. In our study of the field theory evolution, we find no evidence for a "bounce" from a big crunch to a big bang. Instead, it appears that the big bang is a rare fluctuation from a generic equilibrium quantum gravity state.

  2. Holographic Description of AdS Cosmologies

    OpenAIRE

    Hertog, Thomas; Horowitz, Gary T.

    2005-01-01

    To gain insight in the quantum nature of the big bang, we study the dual field theory description of asymptotically anti-de Sitter solutions of supergravity that have cosmological singularities. The dual theories do not appear to have a stable ground state. One regularization of the theory causes the cosmological singularities in the bulk to turn into giant black holes with scalar hair. We interpret these hairy black holes in the dual field theory and use them to compute a finite temperature ...

  3. A Crossing-Symmetric Phase for $AdS_{5} x S^{5}$ Strings

    CERN Document Server

    Beisert, N; López, E; Beisert, Niklas; Hernandez, Rafael; Lopez, Esperanza

    2006-01-01

    We propose an all-order perturbative expression for the dressing phase of the AdS_5 x S^5 string S-matrix at strong coupling. Moreover, we are able to sum up large parts of this expression. This allows us to start the investigation of the analytic structure of the phase at finite coupling revealing a few surprising features. The phase obeys all known constraints including the crossing relation and it matches with the known physical data at strong coupling. In particular, we recover the bound states of giant magnons recently found by Hofman and Maldacena as poles of the scattering matrix. At weak coupling our proposal seems to differ with gauge theory. A possible solution to this disagreement is the inclusion of additional pieces in the phase not contributing to crossing, which we also study.

  4. Towards Timelike Singularity via AdS Dual

    CERN Document Server

    Bhowmick, Samrat

    2016-01-01

    It is well known that Kasner geometry with spacelike singularity can be extended to bulk AdS-like geometry, furthermore one can study field theory on this Kasner space via its gravity dual. In this paper, we show that there exists a Kasner-like geometry with timelike singularity for which one can construct a dual gravity description. We then study various minimal surfaces including spacelike geodesics. Finally, we compute correlators of highly massive operators in the boundary field theory with a geodesic approximation.

  5. Protein domain organisation: adding order

    Directory of Open Access Journals (Sweden)

    Kummerfeld Sarah K

    2009-01-01

    Full Text Available Abstract Background Domains are the building blocks of proteins. During evolution, they have been duplicated, fused and recombined, to produce proteins with novel structures and functions. Structural and genome-scale studies have shown that pairs or groups of domains observed together in a protein are almost always found in only one N to C terminal order and are the result of a single recombination event that has been propagated by duplication of the multi-domain unit. Previous studies of domain organisation have used graph theory to represent the co-occurrence of domains within proteins. We build on this approach by adding directionality to the graphs and connecting nodes based on their relative order in the protein. Most of the time, the linear order of domains is conserved. However, using the directed graph representation we have identified non-linear features of domain organization that are over-represented in genomes. Recognising these patterns and unravelling how they have arisen may allow us to understand the functional relationships between domains and understand how the protein repertoire has evolved. Results We identify groups of domains that are not linearly conserved, but instead have been shuffled during evolution so that they occur in multiple different orders. We consider 192 genomes across all three kingdoms of life and use domain and protein annotation to understand their functional significance. To identify these features and assess their statistical significance, we represent the linear order of domains in proteins as a directed graph and apply graph theoretical methods. We describe two higher-order patterns of domain organisation: clusters and bi-directionally associated domain pairs and explore their functional importance and phylogenetic conservation. Conclusion Taking into account the order of domains, we have derived a novel picture of global protein organization. We found that all genomes have a higher than expected

  6. Attitudes towards ads and age. A study in seniors. The combination of chronological and cognitive age as an effective predictive criterion of attitudes

    OpenAIRE

    Moliner Tena, Miguel Ángel; Estrada Guillén, Marta; Monferrer Tirado, Diego; Sánchez García, Javier

    2014-01-01

    Older adults make up one of the markets with the greatest potential in the future. It is essential that businesses take the diversity within this group into account, and perform segmentation in order to obtain a favorable attitude towards the ad. The potential for segmentation by chronological age has been called into question in recent years, with cognitive age emerging as the main alternative. This research aims to analyses the relationship between the variables of attitude towards the ad, ...

  7. The concept of added value of FM

    DEFF Research Database (Denmark)

    Jensen, Per Anker; van der Voordt, Theo; Coenen, Christian;

    2012-01-01

    Purpose: This chapter presents research perspectives and theoretical reflections on the concept of added value of FM from a variety of academic fields. Methodology: A literature review of the most influential journals within the academic fields of Facilities Management (FM), Corporate Real Estate...... conceptualization of the concept of added value of FM is of utmost importance for further research into the added value of FM and well-considered, evidence- based Value Adding Management in practice. Research limitations: Due to limited time not all FM-related journals could be included in the literature review....... The included journals were analysed over a time period of ten years, with a focus on interesting topics and less on a thematic cross-paper analysis in-depth. Originality/value: Usually the concept of added value is discussed from a mono-disciplinary point of view. The different backgrounds of the authors add...

  8. Holography of non-relativistic string on AdS5 x S5

    International Nuclear Information System (INIS)

    We discuss a holographic dual of a non-relativistic (NR) string on AdS5 x S5 . The NR string can be regarded as a semiclassical string around an AdS2 classical solution corresponding to a straight Wilson line in the gauge-theory side. The quadratic action with respect to the fluctuations is composed of free massive and massless scalars, and free massive fermions on the AdS2 world-sheet. We show that the complete agreement of the spectra between the NR string and a conformal quantum mechanics (CQM). Then we show a holographic relation between normalizable modes of the NR string and wave functions in the CQM. Then it may be argued from this result that an AdS2/CFT1 would be realized in AdS5/CFT4. We can really discuss a GKPW-type relation by considering non-normalizable modes of the NR string in Euclidean signature. Those modes give a source term insertion to the Wilson line, which can also be regarded as a small deformation of it

  9. The effect of Ad

    Institute of Scientific and Technical Information of China (English)

    李小艳

    2010-01-01

    There is the trend that now people appreciate those who are slim and regard slim even thin people beautiful. The thinner a person is, the more beautiful. Women, born to pursuit beauty, try various means to follow the trend. We all watch TV, and find a lot of advertisements on diet. The effect of them is tremendous. We all know the fact that it is not at all the better mouse trap will catch mouse. The sales methods are more important. If an advertisement is very interesting and seemingly effective, people will be lured by the ad and then try some of the products.

  10. Joint assessment of white matter integrity, cortical and subcortical atrophy to distinguish AD from behavioral variant FTD: A two-center study

    Directory of Open Access Journals (Sweden)

    Christiane Möller

    2015-01-01

    Full Text Available We investigated the ability of cortical and subcortical gray matter (GM atrophy in combination with white matter (WM integrity to distinguish behavioral variant frontotemporal dementia (bvFTD from Alzheimer's disease (AD and from controls using voxel-based morphometry, subcortical structure segmentation, and tract-based spatial statistics. To determine which combination of MR markers differentiated the three groups with the highest accuracy, we conducted discriminant function analyses. Adjusted for age, sex and center, both types of dementia had more GM atrophy, lower fractional anisotropy (FA and higher mean (MD, axial (L1 and radial diffusivity (L23 values than controls. BvFTD patients had more GM atrophy in orbitofrontal and inferior frontal areas than AD patients. In addition, caudate nucleus and nucleus accumbens were smaller in bvFTD than in AD. FA values were lower; MD, L1 and L23 values were higher, especially in frontal areas of the brain for bvFTD compared to AD patients. The combination of cortical GM, hippocampal volume and WM integrity measurements, classified 97–100% of controls, 81–100% of AD and 67–75% of bvFTD patients correctly. Our results suggest that WM integrity measures add complementary information to measures of GM atrophy, thereby improving the classification between AD and bvFTD.

  11. Adherence to and appropriateness of anti-osteoporotic treatments in patients aged 50 and over in the Valencia Region (Spain. The ESOSVAL-AD Study

    Directory of Open Access Journals (Sweden)

    Ruiz Vicente

    2011-08-01

    Full Text Available Summary Background A study to evaluate the adherence to and appropriateness of anti-osteoporotic treatments in a cohort of men and women aged 50 and over participating in the ESOSVAL-R study. Methods/Design Design: An observational, longitudinal, prospective cohort study; Study subjects: Men and women aged 50 and over living in the Valencia Region (Spain who initiated treatment between June 15, 2009, and June 15, 2011, in primary healthcare centers with electronic medical records; Data sources: The main data source will be electronic medical records. Measurement of results: Degree of compliance with and persistence of anti-osteoporotic treatments, and the proportion of patients with appropriate anti-osteoporotic treatment in accordance with the most relevant and high impact recommendations with clearly defined treatment algorithms in Spain (the Spanish National Health System guide (2010, the General Practitioners' Society (2007 and the General Directorate for Pharmacy and Medical Products of Madrid (2007, and with the National Osteoporosis Foundation (NOF, 2010, and the International Osteoporosis Foundation guidelines (IOF, 2008; Analysis: 1. Descriptive analysis of patients undergoing treatment and the treatments prescribed; 2. Descriptive analysis of compliance with and persistence of anti-osteoporotic treatments; 3. Analysis of factors associated with compliance with and persistence of treatments by Cox proportional hazard regression models, 4. Descriptive analysis of appropriateness of treatment; 5. Analysis of factors associated with the appropriateness of treatment by multilevel models (4 levels: patient, doctor, Basic Healthcare Zone/Primary Healthcare Center, and Health Area variables. Discussion ESOSVAL-AD will provide information regarding adherence to osteoporosis treatments and the factors associated with a higher or lower adherence (including the appropriateness of the treatment in the Spanish context. A better understanding of this

  12. String in AdS Black Hole: A Thermo Field Dynamic Approach

    OpenAIRE

    Cantcheff, M. Botta; Gadelha, Alexandre L.; Marchioro, Dafni F. Z.; Nedel, Daniel Luiz

    2012-01-01

    Based on Maldacena's description of an eternal AdS-black hole, we reassess the Thermo Field Dynamics (TFD) formalism in the context of the AdS/CFT correspondence. The model studied here involves the maximally extended AdS-Schwarschild solution and two (non-interacting) copies of the CFT associated to the global AdS spacetime, along with an extension of the string by imposing natural gluing conditions in the horizon. We show that the gluing conditions in the horizon define a string boundary st...

  13. A multi-site randomized study to compare the effects of Eye Movement Desensitization and Reprocessing (EMDR) added to TAU versus TAU to reduce craving and drinking behavior in alcohol dependent outpatients: study protocol

    OpenAIRE

    Markus, W; Weert-van Oene, G.H. de; Becker, E.S.; Jong, C.A.J. de

    2015-01-01

    Background Addiction constitutes a major public health problem, and despite treatment, relapse rates remain very high. Preliminary findings suggest that Eye Movement Desensitization and Reprocessing (EMDR), an evidence-based treatment for PTSD, may also reduce craving and relapse rates when applied in substance abuse. This study aims to determine the feasibility, efficacy and effectiveness of EMDR when added to treatment as usual (TAU) for addiction in alcohol dependent outpatients, compared ...

  14. Study on the fermentation properties of added flammulina velutipes juice yogurt%金针菇汁酸奶的发酵特性研究

    Institute of Scientific and Technical Information of China (English)

    刘昭明; 黄翠姬; 苏小娟

    2009-01-01

    Several factors were studied in the fermentation and storage process of flammulina velutipes juice yogurt, including changes of pH, titrable acidity (TA) values, amount of lactic acid and diacetyl and lactobacillus. And the content of amino acids was also measured. The results showed that: when the adding amount of Flammulina velutipes juice was excess 10%, the curd time was shorter and curd quality was better; during the fermentation, the decreasing rate of pH, increasing rate of TA, the amount of lactic acid and diacetyl in the flammulina velutipes juice yogurt were quicker than the controlled sample; in the end of fermentation, the amount of lactic acid tend to be consistent, and the amount of diacetyl increased with the amount of juice; during the storage, when the adding amount of flammulina velutipes juice was excess 10%, the TA value increased slowly, while the laetobacillus decreased slowly. The content of amino acids of yogurt, with juice 10% adding, was excess 12% than the controlled sample. It was concluded that the flammulina velutipes juice was able to promote the growth of lactobacillus and inhibit the post--acidification of yogurt, and the yogurt with flammulina velutipes juice has high nutritional value.%研究金针菇汁酸奶在发酵及贮藏过程中的pH值、滴定酸度、乳酸含量、丁二酮含量和乳酸菌总数的变化以及金针菇汁酸奶的氨基酸含量.结果表明:菇汁添加量为10%以上时,酸奶凝乳时间缩短,凝乳效果好于对照样;发酵过程中,添加菇汁的酸奶的pH值下降的速度、滴定酸度、乳酸及丁二酮增加的速度大于对照样,最终乳酸的含量趋于一致,而丁二酮的含量则是菇汁添加量越大,发酵结束时的含量也越大;菇汁添加量为10%以上时,酸奶在贮藏过程中,滴定酸度增加比较缓慢,乳酸菌总数下降较少;菇汁添加量10%的酸奶的氨基酸含量超过对照样12%.说明菇汁的添加促进了乳酸菌的生长,可以在一

  15. Metastability in bubbling AdS space

    Science.gov (United States)

    Massai, Stefano; Pasini, Giulio; Puhm, Andrea

    2015-02-01

    We study the dynamics of probe M5 branes with dissolved M2 charge in bubbling geometries with SO(4) × SO(4) symmetry. These solutions were constructed by Bena-Warner and Lin-Lunin-Maldacena and correspond to the vacua of the maximally supersymmetric mass-deformed M2 brane theory. We find that supersymmetric probe M2 branes polarize into M5 brane shells whose backreaction creates an additional bubble in the geometry. We explicitly check that the supersymmetric polarization potential agrees with the one found within the Polchinski-Strassler approximation. The main result of this paper is that probe M2 branes whose orientation is opposite to the background flux can polarize into metastable M5 brane shells. These decay to a supersymmetric configuration via brane-flux annihilation. Our findings suggest the existence of metastable states in the mass-deformed M2 brane theory.

  16. Metastability in Bubbling AdS Space

    CERN Document Server

    Massai, Stefano; Puhm, Andrea

    2014-01-01

    We study the dynamics of probe M5 branes with dissolved M2 charge in bubbling geometries with SO(4) x SO(4) symmetry. These solutions were constructed by Bena-Warner and Lin-Lunin-Maldacena and correspond to the vacua of the maximally supersymmetric mass-deformed M2 brane theory. We find that supersymmetric probe M2 branes polarize into M5 brane shells whose backreaction creates an additional bubble in the geometry. We explicitly check that the supersymmetric polarization potential agrees with the one found within the Polchinski-Strassler approximation. The main result of this paper is that probe M2 branes whose orientation is opposite to the background flux can polarize into metastable M5 brane shells. These decay to a supersymmetric configuration via brane-flux annihilation. Our findings suggest the existence of metastable states in the mass-deformed M2 brane theory.

  17. Efficacy and safety of pioglitazone added to alogliptin in Japanese patients with type 2 diabetes mellitus: a multicentre, randomized, double-blind, parallel-group, comparative study.

    Science.gov (United States)

    Kaku, K; Katou, M; Igeta, M; Ohira, T; Sano, H

    2015-12-01

    A phase IV, multicentre, randomized, double-blind, parallel-group, comparative study was conducted in Japanese subjects with type 2 diabetes mellitus (T2DM) who had inadequate glycaemic control, despite treatment with alogliptin in addition to diet and/or exercise therapy. Subjects with glycated haemoglobin (HbA1c) concentrations of 6.9-10.5% were randomized to receive 16 weeks' double-blind treatment with pioglitazone 15 mg, 30 mg once daily or placebo added to alogliptin 25 mg once daily. The primary endpoint was the change in HbA1c from baseline at the end of treatment period (week 16). Both pioglitazone 15 and 30 mg combination therapy resulted in a significantly greater reduction in HbA1c than alogliptin monotherapy [-0.80 and -0.90% vs 0.00% (the least squares mean using analysis of covariance model); p < 0.0001, respectively]. The overall incidence rates of treatment-emergent adverse events were similar among the treatment groups. Pioglitazone/alogliptin combination therapy was effective and generally well tolerated in Japanese subjects with T2DM and is considered to be useful in clinical settings.

  18. Predictors of compliance with a home-based exercise program added to usual medical care in preventing postmenopausal osteoporosis: an 18-month prospective study.

    Science.gov (United States)

    Mayoux-Benhamou, M A; Roux, C; Perraud, A; Fermanian, J; Rahali-Kachlouf, H; Revel, M

    2005-03-01

    This prospective 18-month study was designed to assess long-term compliance with a program of exercise aimed to prevent osteoporosis after an educational intervention and to uncover determinants of compliance. A total of 135 postmenopausal women were recruited by flyers or instructed by their physicians to participate in an educational session added to usual medical care. After a baseline visit and dual-energy X-ray absorptiometry, volunteers participated in a 1-day educational session consisting of a lecture and discussion on guidelines for appropriate physical activity and training in a home-based exercise program taught by a physical therapist. Scheduled follow-up visits were 1, 6, and 18 months after the educational session. Compliance with the exercise program was defined as an exercise practice rate 50% or greater than the prescribed training. The 18-month compliance rate was 17.8% (24/135). The main reason for withdrawal from the program was lack of motivation. Two variables predicted compliance: contraindication for hormone replacement therapy (odds ratio [OR] = 0.13; 95% confidence interval [95% CI], 0.04 to 0.46) and general physical function scores from an SF-36 questionnaire (OR=1.26; 95% CI, 1.03 to 1.5). To a lesser extent, osteoporosis risk, defined as a femoral T-score exercise, only a minority of postmenopausal women adhered to a home-based exercise program after 18 months.

  19. A Simulation Study: The Impact of Random and Realistic Mobility Models on the Performance of Bypass-AODV in Ad Hoc Wireless Networks

    Directory of Open Access Journals (Sweden)

    Baroudi Uthman

    2010-01-01

    Full Text Available To bring VANET into reality, it is crucial to devise routing protocols that can exploit the inherited characteristics of VANET environment to enhance the performance of the running applications. Previous studies have shown that a certain routing protocol behaves differently under different presumed mobility patterns. Bypass-AODV is a new optimization of the AODV routing protocol for mobile ad-hoc networks. It is proposed as a local recovery mechanism to enhance the performance of the AODV routing protocol. It shows outstanding performance under the Random Waypoint mobility model compared with AODV. However, Random Waypoint is a simple model that may be applicable to some scenarios but it is not sufficient to capture some important mobility characteristics of scenarios where VANETs are deployed. In this paper, we will investigate the performance of Bypass-AODV under a wide range of mobility models including other random mobility models, group mobility models, and vehicular mobility models. Simulation results show an interesting feature that is the insensitivity of Bypass-AODV to the selected random mobility model, and it has a clear performance improvement compared to AODV. For group mobility model, both protocols show a comparable performance, but for vehicular mobility models, Bypass-AODV suffers from performance degradation in high-speed conditions.

  20. Preliminary design studies of a 100 MeV H-/H+ LINAC as injector for SNS synchrotron/ADS LINAC

    Indian Academy of Sciences (India)

    S A Pande; Moonooku Prasad; Nita Kulkarni; P R Hannurkar

    2002-11-01

    It is proposed to construct a spallation neutron source (SNS) at Centre for Advanced Technology (CAT) based on a 1 GeV proton synchrotron with 100 MeV H- LINAC as injector. Additionally, the LINAC can form the first 100 MeV part of a 1 GeV proton LINAC to be built in future for accelerator driven system (ADS) applications. We are exploring a configuration of the 100 MeV LINAC which will consist of an H- ion source, a 4–6 MeV RFQ followed either by a 20 MeV drift tube LINAC (DTL) and 100 MeV separated function drift tube LINAC (SDTL) or a coupled cavity drift tube LINAC (CCDTL) structure. In this paper, we present the results of our preliminary physics design studies of the RFQ–SDTL, RFQ–CCDTL and RFQ–DTL–SDTL configurations. The design of the 4.5 MeV RFQ is discussed along with the matching sections between the RFQ–SDTL/DTL and RFQ–CCDTL. The choice of the accelerator configuration and that of various parameters of the individual accelerator structures under consideration are discussed. The design objectives are to arrive at a configuration which eases heat removal for CW operation and which is less prone to halo formation in order to reduce the beam loss at higher energies.

  1. Study the Effect of Value-Added of Services Sector on Forecasting of Electricity Demand in Services Sector due to Price Reform

    Directory of Open Access Journals (Sweden)

    Sayed Mahdi Mostafavi

    2016-07-01

    Full Text Available Electrical energy is as one of the important effective factors on economic growth and development. In recent decades, numerous studies in different countries to estimate and forecast electricity demand in different parts of the economy have been made. In this paper, using the method ARDL, estimation and forecasting of electricity demand in the services sector of Iran are determined for the time period from 1983 to 2012. Estimated equations show that the added value of the services sector and a significant positive impact on the demand for electricity in this sector. The price elasticity for services sector is smaller than 1 due to low electricity prices and subsidized electricity. Hence, electricity prices have little impact on the demand for electricity. The results of the estimate represents a long-term relationship between the variables in the services sector. In this paper, based on amendments to the law on subsidies and estimated values, anticipated electricity demand until the end of the fifth development plan was carried out. The results indicate an increase in power consumption in the services sector.

  2. 氟化牛奶中氟的生物利用率研究%A study on the bioavailability of fluoride added into milk

    Institute of Scientific and Technical Information of China (English)

    王文辉; 卞金有; 曹采方

    2001-01-01

    目的观察氟化牛奶中氟的生物利用率。方法运用药物代谢动力学的方法及交叉对照的实验方法,观察了8名受试者分别饮用氟化牛奶和氟水后血氟及尿氟水平的变化。结果血药浓度法测得氟化牛奶中氟的生物利用率为80.2%,尿药浓度法测得氟化牛奶中氟的生物利用率为84.8%,与氟水相比约低20.0%。结论氟化牛奶中氟的生物利用率是足够高的。%Objective To assess the bioavailability of fluoride added into milk. Methods Eight subjects were studied by testing fluoride levels in blood and urine samples collected after drinking fluoridated milk and fluoridated water respectively, according to pharmacokinitics and cross control method. Results The bioavailability of fluoride in fluoridated milk reached 80.2% in blood analysis and 84.8% in urine analysis. The result was about 20.0% lower as compared with fluoridated water. Conclusion Fluoride bioavailability in fluoridated milk is still high and sufficient.

  3. A Relational Approach to the Study of Religious Survival Units

    DEFF Research Database (Denmark)

    Reeh, Niels

    2012-01-01

    , a religion can be defined and studied as the result of complex set of dynamic relations, where a central tenet of a religion is that it relates to the significant religious other. As such religion is not a stable phenomenon but embedded in a dynamic historical process, which can explain the difficulties...

  4. Randall-Sundrum with AdS(7)

    CERN Document Server

    Bao, R; Bao, Ruoyu; Lykken, Joseph

    2005-01-01

    In the same sense that AdS_5 warped geometries arise naturally from Type IIB string theory with stacks of D3 branes, AdS_7 warped geometries arise naturally from M theory with stacks of M5 branes. We compactify two spatial dimensions of AdS_7 to get AdS_5 x \\Sigma^2, where \\Sigma^2 is e.g. a torus T^2 or a sphere S^2. The metric for \\Sigma inherits the same warp factor as appears in the AdS_5. Bulk fields generically have both Kaluza-Klein and winding modes associated with \\Sigma. In the effective 5d action these will contribute exotic new excitations. We analyze the 5d spectrum in detail for the case of a bulk scalar or a graviton in AdS_5 x T^2, in a setup which mimics the first Randall-Sundrum model. The results display several novel features, some of which might be observed in experiments at the LHC. For example, we obtain TeV scale string winding states without lowering the string scale. This is due to the double warping which is a generic feature of winding states along compactified AdS directions. Expe...

  5. Underweight Seniors May Have Added Alzheimer's Risk

    Science.gov (United States)

    ... fullstory_160278.html Underweight Seniors May Have Added Alzheimer's Risk Study links lower body weight to increased ... older adults' risk of the memory-robbing disorder Alzheimer's disease, new research suggests. The study included 280 ...

  6. Model Catalysis of Ammonia Synthesis ad Iron-Water Interfaces - ASum Frequency Generation Vibrational Spectroscopic Study of Solid-GasInterfaces and Anion Photoelectron Spectroscopic Study of Selected Anionclusters

    Energy Technology Data Exchange (ETDEWEB)

    Ferguson, Michael James [Univ. of California, Berkeley, CA (United States)

    2005-01-01

    The ammonia synthesis reaction has been studied using single crystal model catalysis combined with sum frequency generation (SFG) vibrational spectroscopy. The adsorption of gases N2, H2, O2 and NH3 that play a role in ammonia synthesis have been studied on the Fe(111) crystal surface by sum frequency generation vibrational spectroscopy using an integrated Ultra-High Vacuum (UHV)/high-pressure system. SFG spectra are presented for the dissociation intermediates, NH2 (~3325 cm-1) and NH (~3235 cm-1) under high pressure of ammonia or equilibrium concentrations of reactants and products on Fe(111) surfaces. Special attention was paid to understand how potassium promotion of the iron catalyst affects the intermediates of ammonia synthesis. An Fe(111) surface promoted with 0.2 monolayers of potassium red shifts the vibrational frequencies of the reactive surface intermediates, NH and NH2, providing evidence for weakened the nitrogen-hydrogen bonds relative to clean Fe(111). Spectral features of these surface intermediates persisted to higher temperatures for promoted iron surfaces than for clean Fe(111) surfaces implying that nitrogen-iron bonds are stronger for the promoted surface. The ratio of the NH to NH2 signal changed for promoted surfaces in the presence of equilibrium concentrations of reactants and products. The order of adding oxygen and potassium to promoted surfaces does not alter the spectra indicating that ammonia induces surface reconstruction of the catalyst to produce the same surface morphology. When oxygen is co-adsorbed with nitrogen, hydrogen, ammonia or potassium on Fe(111), a relative phase shift of the spectra occurs as compared to the presence of adsorbates on clean iron surfaces. Water adsorption on iron was also probed using SFG vibrational spectroscopy. For both H2O and D2O, the only spectral feature was in the range of

  7. Strings on AdS2 and the high-energy limit of noncritical M-theory

    Energy Technology Data Exchange (ETDEWEB)

    Horava, Petr; Horava, Petr; Keeler, Cynthia A.

    2007-04-16

    Abstract. Noncritical M-theory in 2+1 dimensions has been defined as a double-scaling limit of a nonrelativistic Fermi liquid on a flat two-dimensional plane. Here we study this noncritical M-theory in the limit of high energies, analogous to the alpha' --> infinity limit of string theory. In the related case of two-dimensional Type 0A strings, it has been argued that the conformal alpha' --> infinity limit leads to AdS_2 with a propagating fermion whose mass is set by the value of the RR flux. Here we provide evidence that in the high-energy limit, the natural ground state of noncritical M-theory similarly describes the AdS_2 x S1 spacetime, with a massless propagating fermion. We argue that the spacetime effective theory in this background is captured by a topological higher-spin extension of conformal Chern-Simons gravity in 2+1 dimensions, consistently coupled to a massless Dirac field. Intriguingly, the two-dimensional plane populated by the original nonrelativistic fermions is essentially the twistor space associated with the symmetry group of the AdS_2 x S1 spacetime; thus, at least in the high-energy limit, noncritical M-theory can be nonperturbatively described as a"Fermi liquid on twistor space.''

  8. Six-dimensional supergravity on S3 x AdS3 and 2d conformal field theory

    International Nuclear Information System (INIS)

    In this paper we study the relation between six-dimensional supergravity compactified on S3 x AdS3 and certain two-dimensional conformal field theories. We compute the Kaluza-Klein spectrum of supergravity using representation theory; these methods are quite general and can also be applied to other compactifications involving anti-de Sitter spaces. A detailed comparison between the spectrum of the two-dimensional conformal field theory and supergravity is made, and we find complete agreement. This applies even at the level of certain non-chiral primaries, and we propose a resolution to the puzzle of the missing states recently raised by Vafa. As a further illustration of the method the Kaluza-Klein spectra of F-theory on M6 x S3 x AdS3 and of M-theory on M6 x S2 x AdS3 are computed, with M6 some Calabi-Yau manifold

  9. Noncommutative Extension of AdS/CFT and Holographic Superconductors

    CERN Document Server

    Pramanik, Souvik; Ghosh, Subir

    2014-01-01

    In this work, we consider a Non-Commutative (NC) extension of AdS-CFT correspondence and its effects on a Holographic Superconductor. NC corrections enter the model from two very different sectors: the NC generalization of Schwarzschild-AdS Black Hole metric and from NC extension of the abelian gauge theory. We study the NC effects on the relations connecting the charge density, critical temperature and condensation operator of the Holographic Superconductor. Our results suggest that generically, NC effects lower the critical temperature of the holographic superconductor.

  10. Tamanho relativo dos órgãos internos de zebuínos sob alimentação restrita e Ad libitum Relative size of internal organs of zebu cattle under restricted and full fed feeding

    Directory of Open Access Journals (Sweden)

    André Mendes Jorge

    1999-04-01

    Full Text Available Os efeitos do nível nutricional e da raça sobre o tamanho relativo dos órgãos internos foram estudados. Sessenta e três machos não-castrados, sendo 16 da raça Gir, 16 Guzerá, 16 Mocho de Tabapuã e 15 da raça Nelore, com idade média de 24 meses e pesos vivos médios iniciais de 376,4; 357,6; 362,0; e 368,6 kg, respectivamente, foram usados. Os animais de cada raça foram divididos, aleatoriamente, em cinco categorias. Uma categoria foi abatida imediatamente (AB; três categorias receberam ad libitum ração contendo 50% de concentrado na matéria seca (categoria 1, 2 e 3, em baias individuais; e uma categoria recebeu a mesma ração, em quantidade restrita, suprindo níveis de proteína e energia 15% acima da mantença (AR. Os animais das categorias 1, 2 e 3 foram abatidos ao atingirem pesos vivos individuais de 405, 450 e 500 kg, respectivamente. No abate, o peso de corpo vazio (PCVZ foi determinado e os pesos dos órgãos internos e víscera foram registrados. Não houve diferenças entre raças nos pesos de fígado, baço, intestinos delgado e grosso, rúmen-retículo, omaso, estômagos e trato gastrintestinal (TGI, quando expressos em 100 kg de PCVZ. A restrição alimentar não influiu nos pesos do coração e dos pulmões, mas reduziu o peso do fígado e os componentes do TGI.The effects of genetic group and nutritional level on relative size of internal organs were studied. Sixty-three bulls, 16 Gyr, 16 Guzera, 15 Nellore and 16 Mocho de Tabapuã, averaging twenty four months of age, and initial live weight of 376.4, 357.6, 362.0, and 368.6 kg, respectively were used. The animals from each breed were randomly assigned to five groups. One group was immediately slaughtered (AB, three groups were full fed, in individual free stall, a diet containing 50% of concentrate on dry matter basis (group1, 2 and 3, and one group was fed with a restricted amount of the same diet to supply the levels of protein and energy 15% above maintenance

  11. The study of genetic polymorphisms related to serotonin in Alzheimer's disease: a new perspective in a heterogenic disorder.

    Science.gov (United States)

    Oliveira, J R; Zatz, M

    1999-04-01

    Genetic and environmental factors have been implicated in the development of Alzheimer's disease (AD), the most common form of dementia in the elderly. Mutations in 3 genes mapped on chromosomes 21, 14 and 1 are related to the rare early onset forms of AD while the epsilon 4 allele of the apolipoprotein E (APOE) gene (on chromosome 19) is the major susceptibility locus for the most common late onset AD (LOAD). Serotonin (5-hydroxytryptamine or 5-HT) is a key neurotransmitter implicated in the control of mood, sleep, appetite and a variety of traits and behaviors. Recently, a polymorphism in the transcriptional control region upstream of the 5-HT transporter (5-HTT) gene has been studied in several psychiatric diseases and personality traits. It has been demonstrated that the short variant(s) of this 5-HTT gene-linked polymorphic region (5-HTTLPR) is associated with a different transcriptional efficiency of the 5-HTT gene promoter resulting in decreased 5-HTT expression and 5-HT uptake in lymphocytes. An increased frequency of this 5-HTTLPR short variant polymorphism in LOAD was recently reported. In addition, another common polymorphic variation in the 5-HT2A and 5-HT2C serotonin receptor genes previously analyzed in schizophrenic patients was associated with auditory and visual hallucinations in AD. These observations suggest that the involvement of the serotonin pathway might provide an explanation for some aspects of the affective symptoms commonly observed in AD patients. In summary, research on genetic polymorphisms related to AD and involved in receptors, transporter proteins and the enzymatic machinery of serotonin might enhance our understanding of this devastating neurodegenerative disorder.

  12. The study of genetic polymorphisms related to serotonin in Alzheimer's disease: a new perspective in a heterogenic disorder

    Directory of Open Access Journals (Sweden)

    Oliveira J.R.M.

    1999-01-01

    Full Text Available Genetic and environmental factors have been implicated in the development of Alzheimer's disease (AD, the most common form of dementia in the elderly. Mutations in 3 genes mapped on chromosomes 21, 14 and 1 are related to the rare early onset forms of AD while the e4 allele of the apolipoprotein E (APOE gene (on chromosome 19 is the major susceptibility locus for the most common late onset AD (LOAD. Serotonin (5-hydroxytryptamine or 5-HT is a key neurotransmitter implicated in the control of mood, sleep, appetite and a variety of traits and behaviors. Recently, a polymorphism in the transcriptional control region upstream of the 5-HT transporter (5-HTT gene has been studied in several psychiatric diseases and personality traits. It has been demonstrated that the short variant(s of this 5-HTT gene-linked polymorphic region (5-HTTLPR is associated with a different transcriptional efficiency of the 5-HTT gene promoter resulting in decreased 5-HTT expression and 5-HT uptake in lymphocytes. An increased frequency of this 5-HTTLPR short variant polymorphism in LOAD was recently reported. In addition, another common polymorphic variation in the 5-HT2A and 5-HT2C serotonin receptor genes previously analyzed in schizophrenic patients was associated with auditory and visual hallucinations in AD. These observations suggest that the involvement of the serotonin pathway might provide an explanation for some aspects of the affective symptoms commonly observed in AD patients. In summary, research on genetic polymorphisms related to AD and involved in receptors, transporter proteins and the enzymatic machinery of serotonin might enhance our understanding of this devastating neurodegenerative disorder.

  13. Canonical energy and hairy AdS black holes

    Science.gov (United States)

    Hyun, Seungjoon; Park, Sang-A.; Yi, Sang-Heon

    2016-08-01

    We propose the modified version of the canonical energy which was introduced originally by Hollands and Wald. Our construction depends only on the Euler-Lagrange expression of the system and thus is independent of the ambiguity in the Lagrangian. After some comments on our construction, we briefly mention on the relevance of our construction to the boundary information metric in the context of the AdS/CFT correspondence. We also study the stability of three-dimensional hairy extremal black holes by using our construction.

  14. Report on the supply and demand of 18O enriched water. Ad hoc committee of the North American Society for the Study of Obesity, 21 January 1999

    International Nuclear Information System (INIS)

    Oxygen-18 is a stable isotope that is used as a tracer for several biomedical applications. The two primary applications are the study of organismal energy expenditure and organ specific utilization of glucose. The former uses 18O along with deuterium to measure carbon dioxide production of free-living animals and humans. Total energy expenditure is calculated from carbon dioxide production using the standard equations of indirect calorimetry. The later uses 18O as a precursor for the production of 18F, a radionuclide that is incorporated into glucose homologues and injected into the circulating blood. When the glucose homologues are taken up by an organ (usually brain), the organ can be imaged using positron emission tomography (PET). Both of these techniques have become major research and, in the case of PET, diagnostic tools during the last decade. This growth in the use of these tools has increased the world-wide demand for 18O in the form of water. In 1998, this demand could not be met by suppliers and significant delivery delays have been encountered by many investigators and clinicians. Some suppliers are quoting delivery delays of a year. These delays have disrupted on-going research and delayed the start of new projects. The shortage has resulted in a price increase of nearly 50% in 18O water. The disruption of 18O supply in 1998 is the second such disruption in the past decade. Commercial suppliers could not provide sufficient product in late 1990 following the forced closure of the US government production facility at Los Alamos Laboratory. Delivery delays lasted throughout 1991. In August of 1998, the council of the North American Association for the Study of Obesity formed an ad hoc committee to gather information regarding the supply and demand for 18O and to investigate potential solutions to the problem

  15. Does an eye-hand coordination test have added value as part of talent identification in table tennis? A validity and reproducibility study.

    Directory of Open Access Journals (Sweden)

    Irene R Faber

    Full Text Available This study investigated the added value, i.e. discriminative and concurrent validity and reproducibility, of an eye-hand coordination test relevant to table tennis as part of talent identification. Forty-three table tennis players (7-12 years from national (n = 13, regional (n = 11 and local training centres (n = 19 participated. During the eye-hand coordination test, children needed to throw a ball against a vertical positioned table tennis table with one hand and to catch the ball correctly with the other hand as frequently as possible in 30 seconds. Four different test versions were assessed varying the distance to the table (1 or 2 meter and using a tennis or table tennis ball. 'Within session' reproducibility was estimated for the two attempts of the initial tests and ten youngsters were retested after 4 weeks to estimate 'between sessions' reproducibility. Validity analyses using age as covariate showed that players from the national and regional centres scored significantly higher than players from the local centre in all test versions (p<0.05. The tests at 1 meter demonstrated better discriminative ability than those at 2 meter. While all tests but one had a positive significant association with competition outcome, which were corrected for age influences, the version with a table tennis ball at 1 meter showed the highest association (r = 0.54; p = 0.001. Differences between the first and second attempts were comparable for all test versions (between -8 and +7 repetitions with ICC's ranging from 0.72 to 0.87. The smallest differences were found for the test with a table tennis ball at 1 meter (between -3 and +3 repetitions. Best test version as part of talent identification appears to be the version with a table tennis ball at 1 meter regarding the psychometric characteristics evaluated. Longitudinal studies are necessary to evaluate the predictive value of this test.

  16. A model of the two-dimensional quantum harmonic oscillator in an $AdS_3$ background

    CERN Document Server

    Frick, Rudolf

    2016-01-01

    In this paper we study a model of the two-dimensional quantum harmonic oscillator in a 3-dimensional anti-de Sitter background. We use a generalized Schr\\"odinger picture in which the analogs of the Schr\\"odinger operators of the particle are independent of both the time and the space coordinates in different representations. The spacetime independent operators of the particle induce the Lie algebra of Killing vector fields of the $AdS_3$ spacetime. In this picture, we have a metamorphosis of the Heisenberg's uncertainty relations.

  17. Ad valorem versus unit taxes

    DEFF Research Database (Denmark)

    Schröder, Philipp J.H.; Sørensen, Allan

    2010-01-01

    Real-world industries are composed from heterogeneous firms and substantial intra-industry reallocations take place, i.e. high productivity firms squeeze out low productivity firms. Previous tax-tool comparisons have not included these central forces of industry structure. This paper examines a...... general equilibrium monopolistic competition model with heterogeneous firms and intra-industry reallocations. We show that the welfare superiority of ad valorem over unit taxes under imperfect competition is not only preserved but amplified. The additional difference between the tools arises because unit...... taxes distort relative prices, which in turn reduces average industry productivity through reallocations (the survival and increased market share of lower productivity firms). Importantly, numerical solutions of the model reveal that the relative welfare loss from using the unit tax increases...

  18. Horizon Conformal Field Theories from $AdS_2$ Black Holes

    CERN Document Server

    Halyo, Edi

    2015-01-01

    We show that the very near horizon region of nonextreme black holes, which can be described by horizon CFTs, are related to $AdS_2$ Rindler spaces. The latter are $AdS_2$ black holes with specific masses and can be described by states of either $D=1$ or $D=2$ CFTs. The central charges of these CFTs and the conformal weights of their states that correspond to the nonextreme black holes exactly match those predicted by the horizon CFTs, providing supporting evidence for this description.

  19. The effect of adding group-based counselling to individual lifestyle counselling on changes in dietary intake. The Inter99 study – a randomized controlled trial

    Directory of Open Access Journals (Sweden)

    Smith Lisa

    2008-11-01

    Full Text Available Abstract Background Few studies have investigated the specific effect of single intervention components in randomized controlled trials. The purpose was to investigate the effect of adding group-based diet and exercise counselling to individual life-style counselling on long-term changes in dietary habits. Methods The study was a randomized controlled intervention study. From a general Danish population, aged 30 to 60 years (n = 61,301, two random sample were drawn (group A, n = 11,708; group B, n = 1,308. Subjects were invited for a health screening program. Participation rate was 52.5%. All participants received individual life-style counselling. Individuals at high risk of ischemic heart disease in group A were furthermore offered group-based life-style counselling. The intervention was repeated for high-risk individuals after one and three years. At five-year follow-up all participants were invited for a health examination. High risk individuals were included in this study (n = 2 356 and changes in dietary intake were analyzed using multilevel linear regression analyses. Results At one-year follow-up group A had significantly increased the unsaturated/saturated fat ratio compared to group B and in men a significantly greater decrease in saturated fat intake was found in group A compared to group B (net change: -1.13 E%; P = 0.003. No differences were found between group A and B at three-year follow-up. At five-year follow-up group A had significantly increased the unsaturated/saturated fat ratio (net change: 0.09; P = 0.01 and the fish intake compared to group B (net change: 5.4 g/day; P = 0.05. Further, in men a non-significant tendency of a greater decrease was found at five year follow-up in group A compared to group B (net change: -0.68 E%; P = 0.10. The intake of fibre and vegetables increased in both groups, however, no significant difference was found between the groups. No differences between groups were found for saturated fat

  20. Extended supersymmetric sigma models in AdS_4 from projective superspace

    CERN Document Server

    Butter, Daniel; Lindstrom, Ulf; Tartaglino-Mazzucchelli, Gabriele

    2012-01-01

    There exist two superspace approaches to describe N=2 supersymmetric nonlinear sigma models in four-dimensional anti-de Sitter (AdS_4) space: (i) in terms of N=1 AdS chiral superfields, as developed in arXiv:1105.3111 and arXiv:1108.5290; and (ii) in terms of N=2 polar supermultiplets using the AdS projective-superspace techniques developed in arXiv:0807.3368. The virtue of the approach (i) is that it makes manifest the geometric properties of the N=2 supersymmetric sigma-models in AdS_4. The target space must be a non-compact hyperkahler manifold endowed with a Killing vector field which generates an SO(2) group of rotations on the two-sphere of complex structures. The power of the approach (ii) is that it allows us, in principle, to generate hyperkahler metrics as well as to address the problem of deformations of such metrics. Here we show how to relate the formulation (ii) to (i) by integrating out an infinite number of N=1 AdS auxiliary superfields and performing a superfield duality transformation. We al...

  1. Classical Klein-Gordon solutions, symplectic structures and isometry actions on AdS spacetimes

    CERN Document Server

    Dohse, Max

    2012-01-01

    We study classical, real Klein-Gordon theory on Lorentzian Anti de Sitter ($\\AdS d$) spacetimes with spatial dimension $d$. We give a complete list of well defined and bounded Klein-Gordon solutions for three types of regions on AdS: slice (time interval times all of space), rod hypercylinder (all of time times solid ball in space), and tube hypercylinder (all of time times solid shell in space). Hypercylinder regions are of natural interest for AdS since the neighborhood of the AdS-boundary is a tube. For the solution spaces of our regions we find the actions induced by the AdS isometry group $\\SOgroup{2,d}$. For all three regions we find one-to-one correspondences between initial data and solutions on the regions. For rod and tube regions this initial data can also be given on the AdS boundary. We calculate symplectic structures associated to the solution spaces, and show their invariance under the isometry actions. We compare our results to the corresponding expressions for $(3\\pn1)$-dimensional Minkowski ...

  2. Chaos and hydrodynamics near AdS$_2$

    CERN Document Server

    Jensen, Kristan

    2016-01-01

    We revisit AdS$_2$ holography with the Sachdev-Ye-Kitaev models in mind. Our main result is to rewrite a generic theory of gravity near an AdS$_2$ throat as a novel hydrodynamics coupled to the correlation functions of a conformal quantum mechanics. This gives a prescription for the computation of $n$-point functions in the dual quantum mechanics. We thereby find that the dual is maximally chaotic.

  3. Solutions in Bosonic String Field Theory and Higher Spin Algebras in AdS

    CERN Document Server

    Polyakov, Dimitri

    2015-01-01

    We find a class of analytic solutions in open bosonic string field theory, parametrized by the chiral copy of higher spin algebra in $AdS_3$. The solutions are expressed in terms of the generating function for the products of Bell polynomials in derivatives of bosonic space-time coordinates $X^m(z)$ of the open string, which form is determined in this work. The products of these polynomials form a natural operator algebra realizations of $W_\\infty$ (area-preserving diffeomorphisms), enveloping algebra of SU(2) and higher spin algebra in $AdS_3$. The class of SFT solutions found can, in turn, be interpreted as the "enveloping of enveloping", or the enveloping of $AdS_3$ higher spin algebra. We also discuss the extensions of this class of solutions to superstring theory and their relations to higher spin algebras in higher space-time dimensions.

  4. Area products for ${\\cal H}^{\\pm}$ in AdS space

    CERN Document Server

    Pradhan, Parthapratim

    2016-01-01

    We derive the thermodynamic products particularly area (or entropy) products of ${\\cal H}^{\\pm}$ for certain class of black holes in AdS space. We show by explicit calculations that more complicated function of event horizon area and Cauchy horizon area is indeed mass-independent. This mass-independent quantities indicate that they could turn out to be an "universal" quantity provided that they depends only on the quantized angular momentum, quantized charges, and cosmological constant. Furthermore, these area (or entropy) product relations for several class of black holes in AdS space gives us strong indication to understanding the nature of non-extremal black hole entropy (both inner and outer) at the microscopic level. Moreover, we compute the famous \\emph{Penrose inequality} for these class of black holes in AdS space. Local thermodynamic stability has been discussed for these black holes and under certain condition these black holes displayed second order phase transition.

  5. Mediated relations: New methods to study online social capital

    NARCIS (Netherlands)

    Vergeer, M.R.M.; Lim, Y.S.; Park, H.W.

    2011-01-01

    The Web has expanded the research agenda for communication scholars to study social capital. In this field of Internet studies, new indicators of social behavior and social relations have surfaced to describe and understand how social capital develops online and what the consequences are for social

  6. Study on some safety-related aspects of tyre use

    NARCIS (Netherlands)

    Jansen, S.T.H.; Schmeitz, A.J.C.; Maas, S.; Rodarius, C.; Akkermans, L.

    2014-01-01

    The tyre is a key component that affects road safety. The European commission has posted a tender aimed to study what measures on a European level can be taken in relation to the use of tyres to improve road safety. The results of this study, supported by a cost benefit analyses and carried out by T

  7. Combined use of Ad-hENDO-VEGI151 and Dexamethasone for prevention and treatment of keratoplasty rejection :an experimental study

    Institute of Scientific and Technical Information of China (English)

    LIU Yin-ping; LIU Lin; PAN Dong-yan; SUN Yan; SHEN Wei; LIU Zhi-Yong

    2006-01-01

    Objective:To evaluate the probability and efficacy of endostatin-vascular endothelial growth inhibitor (VEGI) recombinant adenoviruses combined with dexamethasone on suppressing heterolamellar corneal transplantation rejection. Methods: Heterolamellar corneal transplantation models were established in 64 New Zealand rabbits, which were randomized into 4 groups of 16 rabbits each. After the transplantation, all the 64 right eyes were injected subconjunctively with 0.2 ml saline (saline group), 0. 1ml AdCA13-hENDO-VEGI151 plus 0. 1 ml saline (AdCA13-hENDO-VEGI151 group), 0. 1 ml Dexamethasone (DXM) plus 0.1 ml saline (DXM group), 0. 1 ml AdCA13-hENDO-VEGI151 plus 0.1 ml DXM (AdCA13-hENDO-VEGI151 combined with DXM group) with one time each 3 days for 10 times. Graft survival and ocular surface were observed for 6 weeks. The fusion protein expression was detected by immunohistochemistry 6 weeks after transplantation. Results: Both the CNV index, rejection index and the xenograft rejection rate in the AdCA13-hENDO-VEGI151 combined with DXM group were statistically lower than those in other groups. AdCA13-hENDO-VEGI151 combined with DXM group: 1. 375 0±0. 500 0, 2. 750 0±1. 843 9 and 6.25% respectively 6 week after keratoplasty; Saline group: 3. 437 5±0. 512 3, 8. 812 5±1. 108 7, 100.00%; AdCA13-hENDO-VEGI151 group: 2. 312 5±0. 478 7, 5. 625 0±0. 957 4, 62.50%;DXM group: 3. 000 0±0. 816 5, 5. 562 5±1. 315 0, 56.25% (P<0.01). Immunohistochemical staining showed the fusion protein expressed mainly in corneal epithelium. Conclusion:The fusion protein expressed by the recombinant adenovirus has significant effect on inhibiting neovascularization after heterolamellar corneal transplantation. The topical application of AdCA13-hENDO-VEGI151 combined with DXM suppressed effectively the postoperative xenograft rejection rate of heterolamellar corneal transplantation.

  8. Adding concurrent chemotherapy to postoperative radiotherapy improves locoregional control but Not overall survival in patients with salivary gland adenoid cystic carcinoma—a propensity score matched study

    International Nuclear Information System (INIS)

    To compare the long-term outcomes in patients with salivary gland adenoid cystic carcinoma (SGACC) treated with post-operative chemoradiotherapy (POCRT) versus post-operative radiotherapy (PORT). We retrospectively reviewed the records of 91 SGACC patients treated with surgery followed by PORT (n = 58) or POCRT (n = 33) between 2000 and 2013. Treatment outcomes between groups were compared using propensity score matching (1:1 nearest neighbor). The median radiation dose was 66 Gy, and patients were followed up for a median of 71 months. Cisplatin-based concurrent regimens were the most commonly used chemotherapy schedules. In the entire study cohort, patients undergoing POCRT showed a trend toward higher locoregional control (LRC) rates than those treated with PORT alone at both 5 and 8 years (97 and 97 % versus 84 and 79 %, respectively; P = .066). Distant metastases were the most common form of treatment failure and occurred in 31 (34 %) patients (PORT, n = 17; POCRT, n = 14). After propensity score matching (33 pairs), patients receiving POCRT had 5- and 8 year LRC rates of 97 and 97 %, respectively, compared with 79 and 67 % for patients treated with PORT alone (P = .017). The two groups did not differ significantly in terms of distant metastasis-free survival (DMFS), disease-free survival (DFS), and overall survival (OS). However, a significantly better opioid-requiring pain-free survival (ORPFS) was achieved in POCRT group (P = .038). Subgroup analyses revealed that patients with stage III − IV disease (P = .040 and .017), positive surgical margins (P = .011 and .050), or perineural invasion (P = .013 and .035) had significantly higher 5- and 8 year LRC and ORPFS when treated with POCRT, respectively. In SGACC patients, adding concurrent chemotherapy to PORT may increase LRC and ORPFS rates, particularly in presence of stage III − IV disease, positive surgical margins, or perineural invasion. However, no significant differences in DMFS, DFS, and OS were

  9. Turbulent strings in AdS/CFT

    CERN Document Server

    Ishii, Takaaki

    2015-01-01

    We study nonlinear dynamics of the flux tube between an external quark-antiquark pair in $\\mathcal{N}=4$ super Yang-Mills theory using the AdS/CFT duality. In the gravity side, the flux tube is realized by a fundamental string whose endpoints are attached to the AdS boundary. We perturb the endpoints in various ways and numerically compute the time evolution of the nonlinearly oscillating string. As a result, cusps can form on the string, accompanied by weak turbulence and power law behavior in the energy spectrum. When cusps traveling on the string reach the boundary, we observe the divergence of the force between the quark and antiquark. Minimal amplitude of the perturbation below which cusps do not form is also investigated. No cusp formation is found when the string moves in all four AdS space directions, and in this case an inverse energy cascade follows a direct cascade.

  10. Study on sociological approach to resolve maintenance related social problems

    International Nuclear Information System (INIS)

    This study proposes a sociological approach to resolve maintenance related social problems. As a result of consideration, the followings were found. (1) In general, solutions to some kinds of questions can be deduced from basic laws using some theories or methodologies in the field of the natural science or engineering. The approach to resolve maintenance related social problems is similar to the approach in the natural science or engineering. (2) The points of view based on fundamental human rights, market principles and community principles, and so on, are very important in resolving maintenance related social problems and can be placed as theories or tools for resolution. (3) If such theories or tools for resolving maintenance related social problems as described above are systematically prepared, it is estimated that it becomes very much easier to resolve maintenance related social problems. (author)

  11. Correlation functions in the CFTd/AdSd+1 correspondence

    International Nuclear Information System (INIS)

    Conformal techniques are applied to the calculation of integrals on AdSd+1 space which define correlators of composite operators in the superconformal field theory on the d-dimensional boundary. The 3-point amplitudes for scalar fields of arbitrary mass and gauge fields in the AdS supergravity are calculated explicitly. For three gauge fields we compare in detail with the known conformal structure of the SU(4) flavor current correlator iaJjbJkc> of the N = 4, d = 4 SU(N) SYM theory. Results agree with the free field approximation as would be expected from superconformal non-renormalization theorems. In studying the Ward identity relating iaOIOJ> to IOJ> for (non-marginal) scalar composite operators OI, we find that there is a subtlety in obtaining the normalization of IOJ> from the supergravity action integral

  12. Multi-spike strings in $AdS_3$ with mixed three-form fluxes

    CERN Document Server

    Banerjee, Aritra

    2015-01-01

    The string sigma model in $AdS_3\\times S^3$ supported by mixed three-form fluxes has recently been proved to be integrable which led to a plethora of work in this background including proposals for S matrix and study of semiclassical string profiles. Motivated by this, in this paper, we present a study of `spiky' strings in this background. We analyze the string profiles in detail and also find the dispersion relation between the charges in the `long' string limit after solving the equations of motion perturbatively upto the leading order in the Neveu-Schwarz flux $b$. The $n$-spike dispersion relation is surprisingly found to be not equivalent to the folded string dispersion relation for this background, even when $n=2$. We find that the dispersion for 2 spikes gets corrected by the term $-\\frac{b^2}{2}\\log S$ instead of $\\log^2 S$ as was obtained for folded string in this background. We also discuss the fate of the solution in the limit of pure NS-NS flux.

  13. Voxel-based analysis of cerebral glucose metabolism in AD and non-AD degenerative dementia using statistical parametric mapping

    International Nuclear Information System (INIS)

    Objective: It is know that Alzheimer's disease (AD) and non-AD degenerative dementia have some clinical features in common. The aim of this study was to investigate the specific patterns of regional, cerebral glucose metabolism of AD and non-AD degenerative dementia patients, using a voxel-based 18F-fluorodeoxyglucose (FDG) PET study. Methods: Twenty-three AD patients and 24 non-AD degenerative dementia patients including 9 Parkinson's disease with dementia(PDD), 7 frontal-temporal dementia (FTD), 8 dementia of Lewy bodies (DLB) patients, and 40 normal controls (NC)were included in the study. To evaluate the relative cerebral metabolic rate of glucose (rCMRglc), 18F-FDG PET imaging was performed in all subjects. Subsequently, statistical comparison of PET data with NC was performed using statistical parametric mapping (SPM). Results: The AD-associated FDG imaging pattern typically presented as focal cortical hypometabolism in bilateral parietotemporal association cortes and(or) frontal lobe and the posterior cingulate gyms. As compared with the comparative NC, FTD group demonstrated significant regional reductions in rCMRglc in bilateral frontal, parietal lobes, the cingulate gyri, insulae, left precuneus, and the subcortical structures (including right putamen, right medial dorsal nucleus and ventral anterior nucleus). The PDD group showed regional reductions in rCMRglc in bilateral frontal cortexes, parietotemporal association cortexes, and the subcortical structures (including left caudate, right putamen, the dorsomedial thalamus, lateral posterior nucleus, and pulvinar). By the voxel-by-voxel comparison between the DLB group and NC group, regional reductions in rCMRglc included bilateral occipital cortexes, precuneuses, frontal and parietal lobes, left anterior cingulate gyms, right superior temporal cortex, and the subcortical structures including putamen, caudate, lateral posterior nucleus, and pulvinar. Conclusions: The rCMRglc was found to be different

  14. The Impact of Ad Characteristics on Adolescents’ Attitudes Towards Antismoking Ads

    Directory of Open Access Journals (Sweden)

    Domen Bajde

    2008-03-01

    Full Text Available Smoking exerts a considerable burden not only on those who smoke but just as well on society at large. In response, governments and institutions often resort to advertising which aims to discourage smoking. Unfortunately, our knowledge of the workings of antismoking advertising is detrimentally limited. In particular, the literature delving into the impact of antismoking ad characteristics (e. g., ad content, valence, intensity on the overall effectiveness of antismoking advertising is scarce and contradictory. This empirical study aims to enhance the knowledge of antismoking advertising by presenting results of the survey involving Slovene adolescents. The adolescents were first exposed to advertisements of different antismoking ad contents (for the purpose of this study the term ‘ad content’ refers to types of appeals used in antismoking advertising, ad valence and intensity, and later invited to respond to a number of questions measuring their attitudes toward the ads, their attitudes toward smoking, their intentions to smoke, etc. The results indicate that while the different intensity and valence of ads produce varying attitudes toward the ads, we could not confirm these differences based on ad content. Also, we found that adolescent smokers respond to antismoking ads differently than do their nonsmoking peers. Our findings offer several important implications for antismoking advertisers and the research community interested in the workings of antismoking advertising.

  15. Inflation in AdS/CFT

    Energy Technology Data Exchange (ETDEWEB)

    Freivogel, Ben; /Stanford U., Phys. Dept. /LBL, Berkeley; Hubeny, Veronika E.; /LBL, Berkeley /Durham U., Dept. of Math.; Maloney, Alexander; /Stanford U., Phys. Dept.; Myers, Rob; /Perimeter Inst. Theor. Phys. /Waterloo U.; Rangamani, Mukund; /LBL, Berkeley /Durham U., Dept. of Math.; Shenker, Stephen; /Stanford U., Phys. Dept.

    2005-10-07

    We study the realization of inflation within the AdS/CFT correspondence. We assume the existence of a string landscape containing at least one stable AdS vacuum and a (nearby) metastable de Sitter state. Standard arguments imply that the bulk physics in the vicinity of the AdS minimum is described by a boundary CFT. We argue that large enough bubbles of the dS phase, including those able to inflate, are described by mixed states in the CFT. Inflating degrees of freedom are traced over and do not appear explicitly in the boundary description. They nevertheless leave a distinct imprint on the mixed state. Analytic continuation allows us, in principle, to recover a large amount of nonperturbatively defined information about the inflating regime. Our work also shows that no scattering process can create an inflating region, even by quantum tunneling, since a pure state can never evolve into a mixed state under unitary evolution.We study the realization of inflation within the AdS/CFT correspondence. We assume the existence of a string landscape containing at least one stable AdS vacuum and a (nearby) metastable de Sitter state. Standard arguments imply that the bulk physics in the vicinity of the AdS minimum is described by a boundary CFT. We argue that large enough bubbles of the dS phase, including those able to inflate, are described by mixed states in the CFT. Inflating degrees of freedom are traced over and do not appear explicitly in the boundary description. They nevertheless leave a distinct imprint on the mixed state. Analytic continuation allows us, in principle, to recover a large amount of nonperturbatively defined information about the inflating regime. Our work also shows that no scattering process can create an inflating region, even by quantum tunneling, since a pure state can never evolve into a mixed state under unitary evolution.

  16. A User Study of the Design Issues of PROPIE: A Novel Environment for Enhanced Interaction and Value-Adding of Electronic Documents.

    Science.gov (United States)

    Liew, Chern Li; Foo, Schubert; Chennupati, K. R.

    2001-01-01

    Presents a proposed information environment (PROPIE) for enhanced interaction and value-adding of electronic documents that allows users multiple ways to query intuitively and navigate information in an electronic document. Highlights include user interface technologies; visualization and interactive techniques; query and browsing processes; and…

  17. Metabolomic study of plasma from female mink (Neovison vison) with low and high residual feed intake during restrictive and ad libitum feeding

    DEFF Research Database (Denmark)

    Hedemann, Mette Skou; Damgaard, Birthe Marie

    2012-01-01

    was high during restrictive feeding, e.g. betaine, carnitine, and creatine. During ad libitum feeding the plasma level of metabolites that can be characterized as biomarkers of meat intake (creatinine, carnosine, 1- and 3 methylhistidine) was high. The plasma level of lysophosphatidylcholine species...

  18. Study on relative orbital configuration in satellite formation flying

    Institute of Scientific and Technical Information of China (English)

    Junfeng Li; Xin Meng; Yunfeng Gao; Xiang Li

    2005-01-01

    In this paper, the relative orbital configurations of satellites in formation flying with non-perturbation and J2 perturbation are studied, and an orbital elements method is proposed to obtain the relative orbital configurations of satellites in formation. Firstly, under the condition of nonperturbation, we obtain many shapes of relative orbital configurations when the semi-major axes of satellites are equal.These shapes can be lines, ellipses or distorted closed curves.Secondly, on the basis of the analysis of J2 effect on relative orbital configurations, we find out that J2 effect can induce two kinds of changes of relative orbital configurations. They are distortion and drifting, respectively. In addition, when J2perturbation is concerned, we also find that the semi-major axes of the leading and following satellites should not be the same exactly in order to decrease the J2 effect. The relationship of relative orbital elements and J2 effect is obtained through simulations. Finally, the minimum relation perturbation conditions are established in order to reduce the influence of the J2 effect. The results show that the minimum relation perturbation conditions can reduce the J2 effect significantly when the orbital element differences are small enough, and they can become rules for the design of satellite formation flying.

  19. Thermodynamics of Charged Kalb Ramond AdS black hole in presence of Gauss-Bonnet coupling

    CERN Document Server

    Choudhury, Sayantan

    2013-01-01

    We study the role of the Gauss-Bonnet corrections to the gravity action on the charged AdS black hole in presence of rank 3 antisymmetric Kalb Ramond tensor field strength. Analyzing the branch singularity and the killing horizon, we explicitly derive various thermodynamic parameters and study their behaviour in presence of five dimensional Gauss-Bonnet coupling in AdS space-time. The possibility of a second order phase transition is explored in the light of AdS/CMT correspondence and various critical exponents associated with the discontinuities of the various thermodynamic parameters are determined. We further comment on the universality of the well known Rushbrooke Josephson scaling law and derive a relation between the degree of homogeneity appearing in various free energies and the critical exponents by homogeneous hypothesis test. By making use of the constraints appearing from Hawking temperature and Gauss-Bonnet extended gravity version of Kubo formula we introduce a bound on the five dimensional Gaus...

  20. Half BPS states in AdS_5 x Y^{p,q}

    OpenAIRE

    Gava, Edi; Narain, Kumar S.; Milanesi, Giuseppe; O'Loughlin, Martin

    2007-01-01

    We study a class of solutions of IIB Supergravity which are asymptotically AdS_5 x Y^{p,q}. They have an R x SO(4) x SU(2) x U(1) isometry and preserve half of the 8 supercharges of the background geometry. They are described by a set of second order differential equations that we have found and analysed in a previous paper, where we studied 1/8 BPS states in the maximally supersymmetric AdS_5 x S^5 background. These geometries correspond to certain chiral primary operators of the N=1 superco...

  1. Discrimination in Online Ad Delivery

    OpenAIRE

    Sweeney, Latanya

    2013-01-01

    A Google search for a person's name, such as "Trevon Jones", may yield a personalized ad for public records about Trevon that may be neutral, such as "Looking for Trevon Jones?", or may be suggestive of an arrest record, such as "Trevon Jones, Arrested?". This writing investigates the delivery of these kinds of ads by Google AdSense using a sample of racially associated names and finds statistically significant discrimination in ad delivery based on searches of 2184 racially associated person...

  2. Complexity Growth for AdS Black Holes

    CERN Document Server

    Cai, Rong-Gen; Wang, Shao-Jiang; Yang, Run-Qiu; Peng, Rong-Hui

    2016-01-01

    We further investigate the Complexity-Action (CA) duality conjecture for stationary anti de-Sitter (AdS) black holes and derive some exact results for the growth rate of action within Wheeler-DeWitt (WDW) patch at late time approximation, which is dual to the growth rate of quantum complexity of holographic state. Based on the results from the general $D$-dimensional Reissner-Nordstr\\"{o}m (RN)-AdS black hole, rotating/charged Ba\\~{n}ados-Teitelboim-Zanelli (BTZ) black hole, Kerr-AdS black hole and charged Gauss-Bonnet-AdS black hole, we present a new complexity bound but leave unchanged the conjecture that the stationary AdS black hole in Einstein gravity is the fastest computer in nature.

  3. Respiratory gated PET/CT in a European multicentre retrospective study: added diagnostic value in detection and characterization of lung lesions

    International Nuclear Information System (INIS)

    The aim of our work is to evaluate the added diagnostic value of respiratory gated (4-D) positron emission tomography/computed tomography (PET/CT) in lung lesion detection/characterization in a large patient population of a multicentre retrospective study. The data of 155 patients (89 men, 66 women, mean age 63.9 ± 11.1 years) from 5 European centres and submitted to standard (3-D) and 4-D PET/CT were retrospectively analysed. Overall, 206 lung lesions were considered for the analysis (mean ± SD lesions dimension 14.7 ± 11.8 mm). Maximum standardized uptake values (SUVmax) and lesion detectability were assessed for both 3-D and 4-D PET/CT studies; 3-D and 4-D PET/CT findings were compared to clinical follow-up as standard reference. Mean ± SD 3-D and 4-D SUVmax values were 5.2 ± 5.1 and 6.8 ± 6.1 (p < 0.0001), respectively, with an average percentage increase of 30.8 %. In 3-D PET/CT, 86 of 206 (41.7 %) lesions were considered positive, 70 of 206 (34 %) negative and 50 of 206 (24.3 %) equivocal, while in 4-D PET/CT 117 of 206 (56.8 %) lesions were defined as positive, 80 of 206 (38.8 %) negative and 9 of 206 (4.4 %) equivocal. In 34 of 50 (68 %) 3-D equivocal lesions follow-up data were available and the presence of malignancy was confirmed in 21 of 34 (61.8 %) lesions, while in 13 of 34 (38.2 %) was excluded. In 31 of these 34 controlled lesions, 20 of 34 (58.8 %) and 11 of 34 (32.4 %) were correctly classified by 4-D PET/CT as positive and negative, respectively; 3 of 34 (8.8 %) remained equivocal. With equivocal lesions classified as positive, the overall accuracy of 3-D and 4-D was 85.7 and 92.8 %, respectively, while the same figures were 80.5 and 94.2 % when equivocal lesions were classified as negative. The respiratory gated PET/CT technique is a valuable clinical tool in diagnosing lung lesions, improving quantification and confidence in reporting, reducing 3-D undetermined findings and increasing the overall accuracy in lung lesion detection and

  4. Respiratory gated PET/CT in a European multicentre retrospective study: added diagnostic value in detection and characterization of lung lesions

    Energy Technology Data Exchange (ETDEWEB)

    Guerra, Luca; Elisei, Federica [San Gerardo Hospital, Nuclear Medicine, Monza (Italy); De Ponti, Elena [San Gerardo Hospital, Medical Physics, Monza (Italy); Bettinardi, Valentino; Picchio, Maria [San Raffaele Scientific Institute, Nuclear Medicine, Milan (Italy); National Research Council, Institute for Bioimaging and Molecular Physiology, Milan (Italy); Landoni, Claudio [San Raffaele Scientific Institute, Nuclear Medicine, Milan (Italy); University of Milano-Bicocca, Milan (Italy); Gilardi, Maria Carla [San Raffaele Scientific Institute, Nuclear Medicine, Milan (Italy); National Research Council, Institute for Bioimaging and Molecular Physiology, Milan (Italy); University of Milano-Bicocca, Tecnomed Foundation, Milan (Italy); Versari, Annibale [Scientific Institute Santa Maria Nuova Hospital, Nuclear Medicine, Reggio Emilia (Italy); Fioroni, Federica [Scientific Institute Santa Maria Nuova Hospital, Medical Physics, Reggio Emilia (Italy); Dziuk, Miroslaw [Masovian PET-CT Centre, Department of Nuclear Medicine, Military Institute of Medicine, Warsaw (Poland); Koza, Magdalena [Masovian PET-CT Centre, Euromedic Diagnostic, Warsaw (Poland); Ahond-Vionnet, Renee; Collin, Bertrand [Hopital Pierre Beregovoy, Service de Medecine Nucleaire, Nevers (France); Messa, Cristina [San Gerardo Hospital, Nuclear Medicine, Monza (Italy); National Research Council, Institute for Bioimaging and Molecular Physiology, Milan (Italy); University of Milano-Bicocca, Tecnomed Foundation, Milan (Italy)

    2012-09-15

    The aim of our work is to evaluate the added diagnostic value of respiratory gated (4-D) positron emission tomography/computed tomography (PET/CT) in lung lesion detection/characterization in a large patient population of a multicentre retrospective study. The data of 155 patients (89 men, 66 women, mean age 63.9 {+-} 11.1 years) from 5 European centres and submitted to standard (3-D) and 4-D PET/CT were retrospectively analysed. Overall, 206 lung lesions were considered for the analysis (mean {+-} SD lesions dimension 14.7 {+-} 11.8 mm). Maximum standardized uptake values (SUV{sub max}) and lesion detectability were assessed for both 3-D and 4-D PET/CT studies; 3-D and 4-D PET/CT findings were compared to clinical follow-up as standard reference. Mean {+-} SD 3-D and 4-D SUV{sub max} values were 5.2 {+-} 5.1 and 6.8 {+-} 6.1 (p < 0.0001), respectively, with an average percentage increase of 30.8 %. In 3-D PET/CT, 86 of 206 (41.7 %) lesions were considered positive, 70 of 206 (34 %) negative and 50 of 206 (24.3 %) equivocal, while in 4-D PET/CT 117 of 206 (56.8 %) lesions were defined as positive, 80 of 206 (38.8 %) negative and 9 of 206 (4.4 %) equivocal. In 34 of 50 (68 %) 3-D equivocal lesions follow-up data were available and the presence of malignancy was confirmed in 21 of 34 (61.8 %) lesions, while in 13 of 34 (38.2 %) was excluded. In 31 of these 34 controlled lesions, 20 of 34 (58.8 %) and 11 of 34 (32.4 %) were correctly classified by 4-D PET/CT as positive and negative, respectively; 3 of 34 (8.8 %) remained equivocal. With equivocal lesions classified as positive, the overall accuracy of 3-D and 4-D was 85.7 and 92.8 %, respectively, while the same figures were 80.5 and 94.2 % when equivocal lesions were classified as negative. The respiratory gated PET/CT technique is a valuable clinical tool in diagnosing lung lesions, improving quantification and confidence in reporting, reducing 3-D undetermined findings and increasing the overall accuracy in lung

  5. Does an Eye-Hand Coordination Test Have Added Value as Part of Talent Identification in Table Tennis? A Validity and Reproducibility Study

    Science.gov (United States)

    Faber, Irene R.; Oosterveld, Frits G. J.; Nijhuis-Van der Sanden, Maria W. G.

    2014-01-01

    This study investigated the added value, i.e. discriminative and concurrent validity and reproducibility, of an eye-hand coordination test relevant to table tennis as part of talent identification. Forty-three table tennis players (7–12 years) from national (n = 13), regional (n = 11) and local training centres (n = 19) participated. During the eye-hand coordination test, children needed to throw a ball against a vertical positioned table tennis table with one hand and to catch the ball correctly with the other hand as frequently as possible in 30 seconds. Four different test versions were assessed varying the distance to the table (1 or 2 meter) and using a tennis or table tennis ball. ‘Within session’ reproducibility was estimated for the two attempts of the initial tests and ten youngsters were retested after 4 weeks to estimate ‘between sessions’ reproducibility. Validity analyses using age as covariate showed that players from the national and regional centres scored significantly higher than players from the local centre in all test versions (p<0.05). The tests at 1 meter demonstrated better discriminative ability than those at 2 meter. While all tests but one had a positive significant association with competition outcome, which were corrected for age influences, the version with a table tennis ball at 1 meter showed the highest association (r = 0.54; p = 0.001). Differences between the first and second attempts were comparable for all test versions (between −8 and +7 repetitions) with ICC's ranging from 0.72 to 0.87. The smallest differences were found for the test with a table tennis ball at 1 meter (between −3 and +3 repetitions). Best test version as part of talent identification appears to be the version with a table tennis ball at 1 meter regarding the psychometric characteristics evaluated. Longitudinal studies are necessary to evaluate the predictive value of this test. PMID:24465638

  6. The ADS All Sky Survey

    Science.gov (United States)

    Goodman, Alyssa

    We will create the first interactive sky map of astronomers' understanding of the Universe over time. We will accomplish this goal by turning the NASA Astrophysics Data System (ADS), widely known for its unrivaled value as a literature resource, into a data resource. GIS and GPS systems have made it commonplace to see and explore information about goings-on on Earth in the context of maps and timelines. Our proposal shows an example of a program that lets a user explore which countries have been mentioned in the New York Times, on what dates, and in what kinds of articles. By analogy, the goal of our project is to enable this kind of exploration-on the sky-for the full corpus of astrophysical literature available through ADS. Our group's expertise and collaborations uniquely position us to create this interactive sky map of the literature, which we call the "ADS All-Sky Survey." To create this survey, here are the principal steps we need to follow. First, by analogy to "geotagging," we will "astrotag," the ADS literature. Many "astrotags" effectively already exist, thanks to curation efforts at both CDS and NED. These efforts have created links to "source" positions on the sky associated with each of the millions of articles in the ADS. Our collaboration with ADS and CDS will let us automatically extract astrotags for all existing and future ADS holdings. The new ADS Labs, which our group helps to develop, includes the ability for researchers to filter article search results using a variety of "facets" (e.g. sources, keywords, authors, observatories, etc.). Using only extracted astrotags and facets, we can create functionality like what is described in the Times example above: we can offer a map of the density of positions' "mentions" on the sky, filterable by the properties of those mentions. Using this map, researchers will be able to interactively, visually, discover what regions have been studied for what reasons, at what times, and by whom. Second, where

  7. O PROCESSO AD(EOD - UM NOVO CONCEITO

    Directory of Open Access Journals (Sweden)

    Cristiane Pedrazzi

    2009-01-01

    Full Text Available In this study, cooking of the wood had been investigated until kappa numbers 17 and 14 for a process kinetically modified, elimination of oxygen delignification from the fiber line, and application of AD(EOD and AD(POD techniques for pulp of kappa 17 and AD(EOD and DHT(EPODP for pulp of kappa 14 for the bleaching at 90% ISO. As references, cookings had been carried out until kappa number 17 and 14, oxygen delignification in simple stage and conventional bleaching with sequences A/D(EOD, A/D(EPOD, A/D(EODP and A/D(EPODP for the kappa number 17 pulp and oxygen delignification in simple stage and conventional bleaching sequence DHT(EPODP for pulp of kappa 14. For the pulp of kappa 17, one concluded that processes AD(EOD and AD(POD produced pulp of brightness 90% ISO with good viscosity and brightness stability, using TAC's (totally active chloro relatively low, and it's not necessary the oxygen delignification. Amongst these two processes, the first one revealed to be more attractive to reach the level of 90% ISO brightness. However, comparatively to the reference processes, with oxygen delignification, for example O-A/D(EPODP, process AD(EOD results in increase of the operational cost of the order of US$7-8/odt, including wood and reagents. For the kappa number 14 pulp, process AD(EOD also revealed to be attractive, but the sequence DHT(EPODP was the one that used lower TAC's; however, when compared with the reference (O-DHT(EPODP, it resulted in an increase of operational cost of the order of US$5/odt. Therefore, it can be concluded that the alternative process, without the deslignification with oxygen, is viable only for pulps of lower kappa number.

  8. AD Consolidation for operation beyond 2010

    CERN Document Server

    Eriksson, T

    2008-01-01

    The Antiproton Decelerator (AD), which started up for physics in 2000 and today supplies low-energy antiprotons to the ATRAP, ALPHA, ASACUSA and ACE experiments is based on the ACOL machine from which it still retains most of the components. ACOL construction was completed in 1986 at a total cost of approximately 80 MCHF (excluding infrastructure) which today would correspond to a value of around 160 MCHF. During recent years, a reduction of maintenance and modernisation has been unavoidable due to budgetary restraints. In order to identify the resources needed for continued AD operation beyond 2010 with a reasonably low risk of failures and to avoid increasing maintenance and repair costs, a study has been conducted involving groups from the AB, AT and TS departments. Analysis of breakdown risks, identification of items and costs for consolidation has been done as well as a risk score classification. To be noted is the relatively modest cost of the proposed items in view of the value of the facility and in c...

  9. A guide to gauging ad effectiveness.

    Science.gov (United States)

    Cashill, J

    1987-09-01

    Techniques that have proven successful in private industry can help hospital executives increase their accountability for advertising expenditures. Among these techniques are: The random telephone survey, which can be used to measure whether the hospital's awareness level among the public has increased as the result of a particular ad; The focus group, which assists the hospital in evaluating how it is perceived in relation to other hospitals in its market; The pretest, to determine which ads to eliminate from a campaign and which ones to refine; Educational seminars and direct-response ads; Reliable baseline data on patients and services for use in comparing figures before and after an ad has been used. Above all, careful planning is required to enable the marketing staff to determine what it wishes to accomplish through advertising and to set measurable goals that reflect its expectations for each component of a campaign. PMID:10283482

  10. Causality in AdS/CFT and Lovelock theory

    CERN Document Server

    Camanho, Xian O

    2009-01-01

    We explore the constraints imposed on higher curvature corrections of the Lovelock type due to causality restrictions in the boundary of asymptotically AdS space-time. In the framework of AdS/CFT, this is related to positivity of the energy constraints that arise in conformal collider physics. We present explicit analytic results that fully address these issues for cubic Lovelock gravity in arbitrary dimensions and give the formal analytic results that comprehend general Lovelock theory. The computations can be performed in two ways, both by considering a thermal setup in a black hole background and by studying the scattering of gravitons with a shock wave in AdS. We show that both computations coincide in Lovelock theory. The different helicities, as expected, provide the boundaries defining the region of allowed couplings. We generalize these results to arbitrary higher dimensions and discuss their consequences on the shear viscosity to energy density ratio of CFT plasmas, the possible existence of Boulware...

  11. On the Thermodynamic Geometry and Critical Phenomena of AdS Black Holes

    CERN Document Server

    Sahay, Anurag; Sengupta, Gautam

    2010-01-01

    In this paper, we study various aspects of the equilibrium thermodynamic state space geometry of AdS black holes. We first examine the Reissner-Nordstrom-AdS (RN-AdS) and the Kerr-AdS black holes. In this context, the state space scalar curvature of these black holes are analysed in various regions of their thermodynamic parameter space. This provides important new insights into the structure and significance of the scalar curvature. We further investigate critical phenomena, and the behaviour of the scalar curvature near criticality, for KN-AdS black holes in two mixed ensembles, introduced and elucidated in our earlier work arXiv:1002.2538 [hep-th]. The critical exponents are identical to those in the RN-AdS and Kerr-AdS cases in the canonical ensemble. This suggests an universality in the scaling behaviour near critical points of AdS black holes. Our results further highlight qualitative differences in the thermodynamic state space geometry for electric charge and angular momentum fluctuations of these.

  12. Cigarette Ads and Youth.

    Science.gov (United States)

    Carol, Julia

    1988-01-01

    Points out ways the tobacco industry markets products to youth, including paid advertisements, sponsorship of sporting events, music concerts, and magazines. Relates several focal points for smoking prevention, which include deglamorization of cigarette advertisements and making smoking socially undesirable. (LS)

  13. A STUDY OF SYMBOLIC RELATIONS IN PUBLIC TRANSPORT

    Directory of Open Access Journals (Sweden)

    Andrei B LAN

    2011-08-01

    Full Text Available This paper presents an anthropological, exploratory study of the microsocial world of public transport. Our research focuses on the symbolic relations that are being established (verbally or nonverbally between urban transport travellers that do not know each other and the consequences these relations create. Modern urban configuration forces large numbers of individuals to share public space every day. When this space becomes restrictive, symbolic relations and interpersonal behaviors such as territoriality and personal space management become clearer. Due to overcrowding, public transport is the scene of one of the most restrictive public spaces in a city. The challenge was to observe and interpret daily, casual behaviors through a sociological and psychological scheme, following the methodological tradition established by Erving Goffman and the other symbolic interactionists. Finally, our study generates a number of hypotheses and explanatory models for common practices and behaviors in trams and metros regarded from a symbolic perspective.

  14. Organ preconditioning: the past, current status, and related lung studies

    Institute of Scientific and Technical Information of China (English)

    LUH Shi-ping; YANG Pan-chyr

    2006-01-01

    Preconditioning (PC) has emerged as a powerful method for experimentally and clinically attenuating various types of organ injuries. In this paper related clinical and basic research issues on organ preconditioning issues were systemically reviewed.Since lung injuries, including ischemia-reperfusion and others, play important roles in many clinical results, including thromboembolism, trauma, thermal injury, hypovolemic and endotoxin shock, reimplantation response after organ transplantation, and many respiratory diseases in critical care. It is of interest to uncover methods, including the PCs, to protect the lung from the above injuries. However, related studies on pulmonary PC are relatively rare and still being developed, so we will review previous literature on experimental and clinical studies on pulmonary PC in the following paragraphs.

  15. Different views of AEGIS / AD-6 Experiment (AD facility) AD-6

    CERN Multimedia

    Maximilien Brice

    2012-01-01

    Different views of AEGIS / AD-6 Experiment (AD facility) in July of 2012. The visible parts are the positron accumulator (blue structures on top of of the antiproton extraction line) and the 5T magnet which traps the antiprotons.

  16. Alteration of mTOR signaling occurs early in the progression of Alzheimer disease (AD): analysis of brain from subjects with pre-clinical AD, amnestic mild cognitive impairment and late-stage AD.

    Science.gov (United States)

    Tramutola, Antonella; Triplett, Judy C; Di Domenico, Fabio; Niedowicz, Dana M; Murphy, Michael P; Coccia, Raffaella; Perluigi, Marzia; Butterfield, D Allan

    2015-06-01

    The clinical symptoms of Alzheimer disease (AD) include a gradual memory loss and subsequent dementia, and neuropathological deposition of senile plaques and neurofibrillary tangles. At the molecular level, AD subjects present overt amyloid β (Aβ) production and tau hyperphosphorylation. Aβ species have been proposed to overactivate the phosphoinositide3-kinase (PI3K)/Akt/mammalian target of rapamycin (mTOR) axis, which plays a central role in proteostasis. The current study investigated the status of the PI3K/Akt/mTOR pathway in post-mortem tissue from the inferior parietal lobule (IPL) at three different stages of AD: late AD, amnestic mild cognitive impairment (MCI) and pre-clinical AD (PCAD). Our findings suggest that the alteration of mTOR signaling and autophagy occurs at early stages of AD. We found a significant increase in Aβ (1-42) levels, associated with reduction in autophagy (Beclin-1 and LC-3) observed in PCAD, MCI, and AD subjects. Related to the autophagy impairment, we found a hyperactivation of PI3K/Akt/mTOR pathway in IPL of MCI and AD subjects, but not in PCAD, along with a significant decrease in phosphatase and tensin homolog. An increase in two mTOR downstream targets, p70S6K and 4EBP1, occurred in AD and MCI subjects. Both AD and MCI subjects showed increased, insulin receptor substrate 1, a candidate biomarker of brain insulin resistance, and GSK-3β, a kinase targeting tau phosphorylation. Nevertheless, tau phosphorylation was increased in the clinical groups. The results hint at a link between Aβ and the PI3K/Akt/mTOR axis and provide further insights into the relationship between AD pathology and insulin resistance. In addition, we speculate that the alteration of mTOR signaling in the IPL of AD and MCI subjects, but not in PCAD, is due to the lack of substantial increase in oxidative stress. The figure represents the three different stages of Alzheimer Disease: Preclinical Alzheimer Disease (PCAD), Mild cognitive impairment (MCI

  17. Hospital study reveals strategies for improving media relations.

    Science.gov (United States)

    Fitzgerald, P E; Embrey-Wahl, L

    1987-01-01

    A nationwide study revealed that hospital administrators feel inadequate when dealing with the media, and also think the media does not understand the hospital business. Many strategies are available to counter these problems, including some that emphasize issues related to bed size. PMID:3583722

  18. A randomized study of oral nutritional support versus ad lib nutritional intake during chemotherapy for advanced colorectal and non-small-cell lung cancer.

    Science.gov (United States)

    Evans, W K; Nixon, D W; Daly, J M; Ellenberg, S S; Gardner, L; Wolfe, E; Shepherd, F A; Feld, R; Gralla, R; Fine, S

    1987-01-01

    One hundred ninety-two patients with previously untreated metastatic cancer (102 non-small-cell lung cancer [NSCLC]; 90 colorectal cancer) were randomized to receive either ad lib nutritional intake (control group) or specific nutritional intervention during a 12-week study period when chemotherapy was administered. Those patients randomized to nutritional interventions were counselled to take oral nutrients with caloric intake equal to 1.7 to 1.95 times their basal energy expenditure, depending on their pretreatment nutritional status ("standard" group). An augmented group was counselled to have a caloric intake equivalent to that of the standard group but with 25% of calories provided as protein and additional supplements of zinc and magnesium. Counselling increased caloric intake in both tumor types but reduced weight loss in the short term only for lung cancer patients. Ninety-three NSCLC patients were evaluable for tumor response to vindesine and cisplatin. Overall, only 20.4% of the patients responded, and there were no significant differences in response rates, median time to progression, or overall duration of survival between the nutrition intervention groups and the control group. The tumor response rate to time-sequenced 5-fluorouracil (5-FU) and methotrexate in the 81 evaluable patients with colorectal cancer was only 14.8%, and no significant differences in tumor response rates were noted between the three groups. Furthermore, the median time to progression and overall duration of survival were not different for the control, standard, and augmented groups. Nutritional interventions using dietary counselling had no impact on the percent of planned chemotherapy dose administered, the degree of toxicity experienced by patients, or the frequency of treatment delays. A multivariate prognostic factor analysis demonstrated that for lung cancer, the percent of weight loss, serum albumin concentration, and presence of liver metastases were significant (P less

  19. Woodworking injuries: a comparative study of work-related and hobby-related accidents.

    Science.gov (United States)

    Loisel, F; Bonin, S; Jeunet, L; Pauchot, J; Tropet, Y; Obert, L

    2014-10-01

    The primary objective of this study was to describe the injury characteristics and demographics of patients injured during woodworking activities, upon their arrival to the emergency department in a regional of France where this industry is prevalent. The secondary objective was to compare patient and injury characteristics for work-related and hobby-related accidents. A cohort of 87 patients who had suffered a woodworking accident over a two-year period was evaluated; 79 were available for follow-up. The context and circumstances of the accident, nature and location of the injuries and patient demographics were recorded. Hobby-related accidents accounted for two-thirds of the accidents (51/79). Most of the injured workers were either loggers (35%) or carpenters (46%). The hand was injured in 53 cases (67%). Work-related accidents resulted in significantly more serious consequences in terms of hospital stay, work stoppage, resumption of work or retraining than hobby-related accidents. For the workplace accidents, 86% occurred on new machines; more than 25% of the machines involved in accidents at home were over 15 years. Sixty-eight per cent of workers were wearing their safety gear, while only 31% of those injured during recreational woodworking wore the appropriate gear. Several elements of prevention should be improved: information about the need to maintain the equipment, protect the worker with suitable clothing, and learn which maneuvers are considered hazardous. Safety gear should be regularly inspected in the workplace.

  20. Employment and taxes in Latin America: An empirical study of the effects of payroll, corporate income and value-added taxes on labor outcomes

    Directory of Open Access Journals (Sweden)

    Eduardo Lora

    2016-01-01

    Full Text Available This paper empirically explores the effects of payroll taxes, value-added taxes and corporate income taxes on a variety of labor market outcomes such as participation, employment, informality, and wages. The results are based on nationallevel data of labor variables for 15 Latin American countries, and indicate that the effects of each tax are markedly different and may depend on several aspects of labor and tax institutions. Payroll taxes reduce employment and increase labor costs when their benefits are not valued by workers, but otherwise may increase labor participation and not raise labor costs. Value-added taxes increase informality and reduce skilled labor demand. In contrast, corporate income taxes may help reduce informality, especially among low education workers, but when tax enforcement capabilities are strong they may reduce labor participation and employment of medium- and high-education workers.