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Sample records for adolescence predicts medicine

  1. Medicine use for headache in adolescence predicts medicine use for headache in young adulthood

    DEFF Research Database (Denmark)

    Andersen, Anette; Holstein, Bjørn E; Due, Pernille;

    2009-01-01

    BACKGROUND: Health risk behaviours such as smoking and binge drinking track from adolescence to adulthood. Medicine use is associated with smoking and binge drinking among adolescents. Whether medicine-use behaviour tracks from adolescence to adulthood is unknown. AIM: To examine tracking...

  2. Adolescents' medicine use for headache

    DEFF Research Database (Denmark)

    Holstein, Bjørn E; Andersen, Anette; Fotiou, Anastasios;

    2015-01-01

    BACKGROUND: This study reports secular trends in medicine use for headache among adolescents in 20 countries from 1986 to 2010. METHODS: The international Health Behaviour in School-aged Children (HBSC) survey includes self-reported data about medicine use for headaches among nationally...... representative samples of 11-, 13- and 15-year-olds. We included 20 countries with data from at least three data collection waves, with a total of 380 129 participants. RESULTS: The prevalence of medicine use for headaches varied from 16.5% among Hungarian boys in 1994 to 62.9% among girls in Wales in 1998....... The prevalence was higher among girls than boys in every country and data collection year. The prevalence of medicine use for headaches increased in 12 of 20 countries, most notably in the Czech Republic, Poland, Russia, Sweden and Wales. CONCLUSION: The prevalence of medicine use for headaches among adolescents...

  3. Society for Adolescent Health and Medicine

    Science.gov (United States)

    ... in Health Care LGBT Health Media Use by Adolescents Mental Health Sexual & Reproductive Health Sports Medicine Substance Use Transition to Adult Care Related Organizations Adolescent and Young Adult Clinical Care Resources Resources for ...

  4. Clinical Holistic Medicine: Holistic Adolescent Medicine

    Directory of Open Access Journals (Sweden)

    Søren Ventegodt

    2004-01-01

    Full Text Available The holistic medical approach seems to be efficient and can also be used in adolescent medicine. Supporting the teenager to grow and develop is extremely important in order to prevent many of the problems they can carry into adulthood. The simple consciousness-based, holistic medicine — giving love, winning trust, giving holding, and getting permission to help the patient feel, understand, and let go of negative beliefs — is easy for the physician interested in this kind of practice and it requires little previous training for the physician to be able to care for his/her patient. A deeper insight into the principles of holistic treatment and a thorough understanding of our fellow human beings are making it work even better. Holistic medicine is not a miracle cure, but rather a means by which the empathic physician can support the patient in improving his/her future life in respect to quality of life, health, and functional capacity — through coaching the patient to work on him/herself in a hard and disciplined manner. When the patient is young, this work is so much easier. During our lifetime, we have several emotional traumas arranged in the subconscious mind with the smallest at the top, and it is normal for the person to work on a large number of traumatic events that have been processed to varying degrees. Some traumas have been acknowledged, some are still being explored by the person, and yet others are still preconscious, which can be seen for example in the form of muscle tension. Sometimes the young dysfunctional patient carries severe traumas of a violent or sexual nature, but the physician skilled in the holistic medical toolbox can help the patient on his/her way to an excellent quality of life, full self-expression, a love and sex life, and a realization of his/her talents — all that a young patient is typically dreaming about. Biomedicine is not necessary or even recommended when the physical or mental symptoms are caused

  5. Social class variation in medicine use among adolescents

    DEFF Research Database (Denmark)

    Holstein, Bjørn E; Hansen, Ebba Holme; Due, Pernille

    2004-01-01

    Little is known about social determinants of adolescents' medicine use. The objective was to analyse the association between the family's social class and adolescents' use of medicine for headache, stomachache, difficulties in getting to sleep, and nervousness.......Little is known about social determinants of adolescents' medicine use. The objective was to analyse the association between the family's social class and adolescents' use of medicine for headache, stomachache, difficulties in getting to sleep, and nervousness....

  6. The status of adolescent medicine: building a global adolescent workforce.

    Science.gov (United States)

    Lee, Lana; Upadhya, Krishna K; Matson, Pamela A; Adger, Hoover; Trent, Maria E

    2016-08-01

    Remarkable public health achievements to reduce infant and child mortality as well as improve the health and well-being of children worldwide have successfully resulted in increased survival and a growing population of young people aged 10-24 years. Population trends indicate that the current generation of 1.8 billion young people is the largest in history. However, there is a scarcity of dedicated resources available to effectively meet the health needs of adolescents and young adults worldwide. Growing recognition of the pivotal roles young people play in the cultures, societies, and countries in which they live has spurred an expanding global movement to address the needs of this special population. Building an effective global workforce of highly-skilled adolescent health professionals who understand the unique biological, psychological, behavioral, social, and environmental factors that affect the health of adolescents is a critical step in addressing the health needs of the growing cohort of young people. In this review, we aim to: 1) define a global assessment of the health needs for adolescents around the world; 2) describe examples of current training programs and requirements in adolescent medicine; 3) identify existing gaps and barriers to develop an effective adolescent health workforce; and 4) develop a call for targeted actions to build capacity of the adolescent health workforce, broaden culturally relevant research and evidence-based intervention strategies, and reinforce existing interdisciplinary global networks of youth advocates and adolescent health professionals to maximize the opportunities for training, research, and care delivery. PMID:26167974

  7. Predicting Resilience in Sexually Abused Adolescents

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    Williams, Javonda; Nelson-Gardell, Debra

    2012-01-01

    This research examined factors that predicted resilience in sexually abused adolescents. Using Bronfenbrenner's Process-Person-Context-Time (PPCT) ecological model, this study considered the proximal and distal factors that would contribute to adolescents' reactions to sexual victimization. This correlational study used hierarchical regression…

  8. Music therapy and music medicine for children and adolescents.

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    Yinger, Olivia Swedberg; Gooding, Lori

    2014-07-01

    This article summarizes the research on music therapy and music medicine for children and adolescents with diagnoses commonly treated by psychiatrists. Music therapy and music medicine are defined, effects of music on the brain are described, and music therapy research in psychiatric treatment is discussed. Music therapy research with specific child/adolescent populations is summarized, including disorders usually diagnosed in childhood, substance abuse, mood/anxiety disorders, and eating disorders. Clinical implications are listed, including suggestions for health care professionals seeking to use music medicine techniques. Strengths and weaknesses of music therapy treatment are discussed, as well as areas for future research.

  9. Health complaints and use of medicines among adolescents in Malta

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    Darmanin Ellul R

    2008-09-01

    Full Text Available Objective: To investigate self-reported health complaints and the use of medicines among adolescents in Malta.Methods: A self-administered questionnaire was used to survey self-reported health complaints, the use and the sources of medicines that had been accessed, during the preceding 3 months among adolescents attending secondary schools in Malta. A stratified random sample design generated a sample size of 514 students. The health complaints and use of medicines that were investigated included ear problems/hay fever/cold/cough, headache, skin problems, sport injuries, indigestion/diarrhoea/constipation, eye problems and menstrual pain (for girls. The use of vitamins and antibiotics was also investigated. Results: A total of 477 students participated in the final data collection. Correct information was submitted by 474 students, (aged 14-16 years, who formed the analytical sample, of which 53.8% were girls. The students reported a mean number of 2.70 (SD = 1.39 out of a total of 7 health complaints and 90.3% reported using at least 1 medicine during the preceding 3 months. The community pharmacy was cited as the most commonly accessed source for most of the medicines that were investigated. A proportion of 24.3% of the students had taken at least 1 medicine without adult guidance during the preceding 3 months. Almost 10% of those who had taken antibiotics, had accessed them from the home medicine cabinet.Conclusion: A high proportion of adolescents in Malta reported the use of medicines to alleviate the symptoms of common health complaints. This result is concordant with previous research carried out in the United Kingdom, Germany, Slovakia and Kuwait. A considerable proportion of students in this study had obtained medicines without adult guidance and accessed antibiotics from the home medicine cabinet. This highlights the importance of carefully designed education programs for adolescents that will integrate information about the proper use

  10. Sense of coherence and medicine use for headache among adolescents

    DEFF Research Database (Denmark)

    Koushede, Vibeke; Holstein, Bjørn E

    2009-01-01

    OBJECTIVE: To examine the association between headache, sense of coherence (SOC), and medicine use for headaches in a community-based sample of adolescents. METHODS: Epidemiological cross-sectional study, encompassing 20 out of 23 schools in the network of health-promoting schools in the county...... to bullying, and headache frequency showed increasing odds for medicine use for headaches (hereafter: medicine use) by decreasing SOC. There was no association between SOC and medicine use among students with a rare experience of headaches but a significant and graded association among students with at least...

  11. Young adolescents' use of medicine for headache:

    DEFF Research Database (Denmark)

    Holstein, Bjørn E; Andersen, Anette; Krølner, Rikke;

    2008-01-01

    associated with medicine use. METHODS: Cross-sectional study in eight schools where all fifth and seventh grade students (11- and 13-year-olds) answered a questionnaire about socio-demographic factors, health and medicine use. Response rate: 84.0%, n = 595. RESULTS: The reported prevalence of headache at...... children who mentioned three or more sources of supply was 4.53 (95% CI 2.63-7.83) in a multivariate model controlled for sex, age and prevalence of headache. Use of medicine was also associated with availability at home (OR = 1.51, 1.01-2.27) and accessibility (OR = 2.49, 1.57-3.93). CONCLUSION: Medicine...

  12. Exploring adolescent complementary/alternative medicine (CAM) use in Canada.

    Science.gov (United States)

    Patterson, Chris; Arthur, Heather; Noesgaard, Charlotte; Caldwell, Patricia; Vohra, Julie; Francoeur, Chera; Swinton, Marilyn

    2008-01-01

    A qualitative study using a grounded theory approach investigated adolescents' perceptions about complementary/alternative medicine (CAM) use. Adolescents, attending a clinic at the Canadian College of Naturopathic Medicine, were interviewed after receiving ethics approval. Data were collected using semi-structured interviews. The decision of adolescents to use CAM was based within the context of their world and how it shaped influencing factors. Factors that influenced adolescents' decision to use CAM were identified as certain personality traits, culture, media, social contacts and the ability of CAM providers to develop therapeutic relationships. The barriers and benefits of CAM use influenced evaluation of choices. The importance of barriers in limiting freedom of choice in health care decisions should be investigated by practitioners as they provide care to adolescents. Health care planning for integrative models of care requires determining the "right" blend of expertise by knowing interprofessional boundaries, determining mixed skill sets to provide the essential services and ensuring appropriate regulation that allows practitioners to use their full scope of practice. PMID:18202985

  13. Predicting achievement in mathematics in adolescent students

    OpenAIRE

    Zupančič, Maja; PUKLEK LEVPUŠČEK, Melita; Sočan, Gregor

    2015-01-01

    The study examined individual factors and social factors that influence adolescent studentsʼ achievement in mathematics. The predictive model suggested direct positive effects of student intelligence, self-rated openness and parental education on achievement in mathematics, whereas direct effects of extraversion on measures of achievement were negative. Indirect positive effects of intelligence, self-rated conscientiousness, student-perceived mathematics teacherʼs press for understanding and ...

  14. [New horizons in medicine. Complexity and predictability in internal medicine].

    Science.gov (United States)

    Guarini, G; Onofri, E

    1993-10-01

    Being a highly sophisticated structure, the human body should be considered on a physical level as a whole of inter-correlated non-linear dynamic systems, which are by definition, complex systems because they are always conditioned in their operativity by numerous variables. We must draw attention to the opportunity that within the field of medical science the concept of complexity referring to diagnostic, therapeutic and prognostical problems, is distinct between structural and functional. The functional complexity of a system, a phenomena, an event, MY be recognized in its dynamics, only if analysed using modern methods recently brought to light, on the relationship which exist between classic determinism and deterministic chaos. Furthermore, also on practical level, the recent discoveries on the general principles, which are at the base of the functional complexity of non-linear dynamic systems, demonstrate exactly how fragile is the probabilistic predictability which guides a doctor in clinical reasoning in all its various stages; in the gathering of anamnestic and objective data; in the programming the researches aimed at confirming the validness of the diagnosis; in the therapy aimed at reaching the best possible results; in the prognosis which summarize the destiny of the binomial patient illness. The scientific enunciate of universal nature, which demonstrate how, from a tiny uncertainty in the initial functional data of a system, of a phenomena, of an event can unleash a condition of absolute unpredictability, find daily confirmation in both clinical and experimental medicine.(ABSTRACT TRUNCATED AT 250 WORDS) PMID:8235036

  15. Meal frequencies in early adolescence predict meal frequencies in late adolescence and early adulthood

    DEFF Research Database (Denmark)

    Pedersen, Trine Pagh; Holstein, Bjørn E; Flachs, Esben Meulengracht;

    2013-01-01

    Health and risk behaviours tend to be maintained from adolescence into adulthood. There is little knowledge on whether meal frequencies in adolescence are maintained into adulthood. We investigated whether breakfast, lunch and evening meal frequencies in early adolescence predicted meal frequencies...

  16. Proceedings: Persepectives on adolescent medicine: concepts and program design.

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    Cohen, M I; Litt, R F; Schonberg, S K; Sheehy, A J; Daum, F; Hein, K

    1975-01-01

    The concepts and goals of a program in adolescent medicine should include development of a capability to focus on current health needs of youth in a variety of settings; to plan clinical services to meet those needs with the flexibility necessary to respond to changing future requirements; and to deliver service within such a context while simulataneously creating a milieu conducive to education and investigation into the very process and definition of adolescence. The Division of Adolescent Medicine at Montefiore Hospital and Medical Center was designed 7 years ago to fulfill these goals and consequently may serve others as a functional model for health care delivery to teenagers. The Division is comprised of: (1) a 37 bed in-patient unit; (2) a hospital-based ambulatory program including general diagnostic and follow-up services, as well as a speciality service capability in the areas of gynecology and family planning, cardiology, gastroenterology and nutrition; (3) primary care health services within teenage dentention and prison facilities; (4) addictive disease diagnostic and treatment programs; (5) school health programs from intermediate school through college levels, and (6) the division also performs supportive and consultative functions for a variety of community-based agencies. Within the programatic design approximately 70,000 adolescents have been served. The cornerstone of the educational and investigative efforts has been the concept that all the above six functional units are clinical laboratories and classrooms so that training and research activities are integral parts of each of the service areas. This program design is continually undergoing revision and refinement so as to remain ever-responsive to new and emerging problems to meet additional training demands and, most importantly, to permit and encourage creativity and growth patients and staff. PMID:1065206

  17. Nuclear Medicine in Pediatric and Adolescent Tumors.

    Science.gov (United States)

    Kiratli, Pınar Özgen; Tuncel, Murat; Bar-Sever, Zvi

    2016-07-01

    Nuclear medicine has an important role in the management of many cancers in pediatric age group with multiple imaging modalities and radiopharmaceuticals targeting various biological uptake mechanisms. 18-Flourodeoxyglucose is the radiotracer of choice especially in patients with sarcoma and lymphoma. (18)FDG-PET, for sarcoma and lymphomas, is proved to be superior to conventional imaging in staging and therapy response. Although studies are limited in pediatric population, (18)FDG-PET/CT has found its way through international guidelines. Limitations and strengths of PET imaging must be noticed before adapting PET imaging in clinical protocols. Established new response criteria using multiple parameters derived from (18)FDG-PET would increase the accuracy and repeatability of response evaluation. Current data suggest that I-123 metaiodobenzylguanidine (MIBG) remains the tracer of choice in the evaluation of neuroblastoma (NB) because of its high sensitivity, specificity, diagnostic accuracy, and prognostic value. It is valuable in determining the response to therapy, surveillance for disease recurrence, and in selecting patients for I-131 therapy. SPECT/CT improves the diagnostic accuracy and the interpretation confidence of MIBG scans. (18)FDG-PET/CT is an important complementary to MIBG imaging despite its lack of specificity to NB. It is valuable in cases of negative or inconclusive MIBG scans and when MIBG findings underestimate the disease status as determined from clinical and radiological findings. F-18 DOPA is promising tracer that reflects catecholamine metabolism and is both sensitive and specific. F-18 DOPA scintigraphy provides the advantages of PET/CT imaging with early and short imaging times, high spatial resolution, inherent morphologic correlation with CT, and quantitation. Regulatory and production issues currently limit the tracer's availability. PET/CT with Ga-68 DOTA appears to be useful in NB imaging and may have a unique role in selecting

  18. The medicine use and corresponding subjective health complaints among adolescents, a cross-national survey

    DEFF Research Database (Denmark)

    Gobina, Inese; Välimaa, Raili; Tynjälä, Jorma;

    2011-01-01

    was strongly associated with the frequency of health complaints. The prevalence of both medicine use and health complaints was higher among girls than boys. Boys and girls with weekly health complaints were both similarly likely to report elevated rates of medicine use. CONCLUSIONS: The findings indicated...... that adolescents who report more frequent recurrent health complaints are also more likely to report more frequent medicine use for their health complaints. Adolescent boys with weekly health complaints have the same risk of medicine use as girls with weekly health complaints. The importance of educating school...... of the frequency of medicine use, age, gender and country of residence, on the likelihood of medicine use was assessed using multilevel multivariate logistic regression, with separate analyses for boys and girls. RESULTS: Both health complaints and medicine use were common among adolescents. Medicine use...

  19. The foundations of interdisciplinary fellowship training in adolescent medicine in the United States.

    Science.gov (United States)

    Bravender, Terrill

    2016-08-01

    The field of adolescent medicine, having developed from the specialty of Pediatrics, encompasses a holistic and developmental approach from its very origin. While its foundations were in medicine, early leaders in the field emphasized the importance of mental health care as well as nutrition, public health, and social justice. As the specialty became further established in the US with the creation of an academic society, board certification and training program accreditation, the interdisciplinary nature of adolescent medicine practice and training became formalized. This formal recognition brought with it strict guidelines with regards training and board certification. Despite the often Byzantinian training requirements, an interdisciplinary approach forms the core of adolescent medicine practice, and the incorporation of interdisciplinary training is a necessity for graduate medical education programs in the field of adolescent medicine. PMID:26115494

  20. Empathy development in adolescence predicts social competencies in adulthood.

    Science.gov (United States)

    Allemand, Mathias; Steiger, Andrea E; Fend, Helmut A

    2015-04-01

    This 23-year study explored the predictive associations between empathy development in adolescence and self-reported social competencies and outcomes in adulthood. Participants were 1,527 adults aged 35 years (48.3% female). The predictor variable (adolescent empathy) was measured yearly at the ages of 12 to 16 years. The outcome variables (adult empathy, communication skills, social integration, relationship satisfaction, and conflicts in relationships) were measured at the age of 35 years. Five important results stand out. First, longitudinal measurement invariance was established for the measure of adolescent empathy. Second, empathy tended to increase during the adolescent years. Third, significant interindividual differences in level and change of adolescent empathy were found. Fourth, gender was related to level of adolescent empathy, favoring girls over boys. Fifth, not only level but also change in adolescent empathy predicted individual differences in social competencies in adulthood two decades later. These findings demonstrate that developmental processes that are relevant for adjustment reveal long-term social consequences beyond the adolescent years.

  1. Predictable Chronic Mild Stress in Adolescence Increases Resilience in Adulthood

    OpenAIRE

    Suo, Lin; Zhao, Liyan; Si, Jijian; Liu, Jianfeng; Zhu, Weili; Chai, Baisheng; Zhang, Yan; Feng, Jiajia; Ding, Zengbo; Luo, Yixiao; Shi, Haishui; Shi, Jie; Lu, Lin

    2013-01-01

    Stress in adolescence has been widely demonstrated to have a lasting impact in humans and animal models. Developmental risk and protective factors play an important role in the responses to stress in adulthood. Mild-to-moderate stress in adolescence may resist the negative impacts of adverse events in adulthood. However, little research on resilience has been conducted. In this study, we used a predictable chronic mild stress (PCMS) procedure (5 min of daily restraint stress for 28 days) in a...

  2. Prenatal Substance Exposure: What Predicts Behavioral Resilience by Early Adolescence?

    OpenAIRE

    Liebschutz, Jane; Crooks, Denise; Rose-Jacobs, Ruth; Cabral, Howard J.; Heeren, Timothy C.; Gerteis, Jessie; Appugliese, Danielle P.; Heymann, Orlaith D.; Lange, Allison V.; Frank, Deborah A.

    2015-01-01

    Understanding behavioral resilience among at-risk adolescents may guide public policy decisions and future programs. We examined factors predicting behavioral resilience following intrauterine substance exposure (IUSE) in a prospective longitudinal birth-cohort study of 136 early adolescents (age 12.4–15.9) at-risk for poor behavioral outcomes. We defined behavioral resilience as a composite measure of lack of early substance use initiation (before age 14), lack of risky sexual behavior, or l...

  3. Evolutionary prediction of medicinal properties in the genus Euphorbia L.

    Science.gov (United States)

    Ernst, Madeleine; Saslis-Lagoudakis, C. Haris; Grace, Olwen M.; Nilsson, Niclas; Simonsen, Henrik Toft; Horn, James W.; Rønsted, Nina

    2016-01-01

    The current decrease of new drugs brought to the market has fostered renewed interest in plant-based drug discovery. Given the alarming rate of biodiversity loss, systematic methodologies in finding new plant-derived drugs are urgently needed. Medicinal uses of plants were proposed as proxy for bioactivity, and phylogenetic patterns in medicinal plant uses have suggested that phylogeny can be used as predictive tool. However, the common practice of grouping medicinal plant uses into standardised categories may restrict the relevance of phylogenetic predictions. Standardised categories are mostly associated to systems of the human body and only poorly reflect biological responses to the treatment. Here we show that medicinal plant uses interpreted from a perspective of a biological response can reveal different phylogenetic patterns of presumed underlying bioactivity compared to standardised methods of medicinal plant use classification. In the cosmopolitan and pharmaceutically highly relevant genus Euphorbia L., identifying plant uses modulating the inflammatory response highlighted a greater phylogenetic diversity and number of potentially promising species than standardised categories. Our interpretation of medicinal plant uses may therefore allow for a more targeted approach for future phylogeny-guided drug discovery at an early screening stage, which will likely result in higher discovery rates of novel chemistry with functional biological activity. PMID:27464466

  4. Predictive factors of alcohol and tobacco use in adolescents

    Directory of Open Access Journals (Sweden)

    Alicia Alvarez-Aguirre

    2014-12-01

    Full Text Available OBJECTIVES: to analyze the effect of self-esteem, assertiveness, self-efficacy and resiliency on alcohol and tobacco consumption in adolescents.METHOD: a descriptive and correlational study was undertaken with 575 adolescents in 2010. The Self-Esteem Scale, the Situational Confidence Scale, the Assertiveness Questionnaire and the Resiliency Scale were used.RESULTS: the adjustment of the logistic regression model, considering age, sex, self-esteem, assertiveness, self-efficacy and resiliency, demonstrates significance in the consumption of alcohol and tobacco. Age, resiliency and assertiveness predict alcohol consumption in the lifetime and assertiveness predicts alcohol consumption in the last year. Similarly, age and sex predict tobacco consumption in the lifetime and age in the last year.CONCLUSION: this study can offer important information to plan nursing interventions involving adolescent alcohol and tobacco users.

  5. Self-Control Assessments and Implications for Predicting Adolescent Offending.

    Science.gov (United States)

    Fine, Adam; Steinberg, Laurence; Frick, Paul J; Cauffman, Elizabeth

    2016-04-01

    Although low self-control is consistently related to adolescent offending, it is unknown whether self-report measures or laboratory behavior tasks yield better predictive utility, or if a combination yields incremental predictive power. This is particularly important because developmental theory indicates that self-control is related to adolescent offending and, consequently, risk assessments rely on self-control measures. The present study (a) examines relationships between self-reported self-control on the Weinberger Adjustment Inventory with Go/No-Go response inhibition, and (b) compares the predictive utility of both assessment strategies for short- and long-term adolescent reoffending. It uses longitudinal data from the Crossroads Study of male, first-time adolescent offenders ages 13-17 (N = 930; 46 % Hispanic/Latino, 37 % Black/African-American, 15 % non-Hispanic White, 2 % other race). The results of the study indicate that the measures are largely unrelated, and that the self-report measure is a better indicator of both short- and long-term reoffending. The laboratory task measure does not add value to what is already predicted by the self-report measure. Implications for assessing self-control during adolescence and consequences of assessment strategy are discussed. PMID:26792266

  6. Predictors for adolescent visits to practitioners of complementary and alternative medicine in a total population (the Young-HUNT Studies.

    Directory of Open Access Journals (Sweden)

    Aslak Steinsbekk

    Full Text Available AIM: To investigate the factors predicting adolescent visits to practitioners of complementary and alternative medicine (CAM. METHODS: A longitudinal cohort study conducted in an adolescent total population in Central Norway (The Nord-Trøndelag Health Studies (HUNT. In Young-HUNT 1, all inhabitants aged 13 to 19 years (N = 8944, 89% response rate were invited to participate, and the youngest group (13 to 15 year olds was surveyed again 4 years later (Young-HUNT 2, N = 2429, 82% response rate. The participants completed a comprehensive questionnaire on health and life style which included a question regarding visits to a CAM practitioner in the last 12 months. RESULTS: One in eleven (8.7%, 95%CI 7.6-9.8% had visited a CAM practitioner, an increase of 26% in 4 years (1.8% points. The final multivariable analysis predicted increased odds of an adolescent becoming a CAM visitor four years later (p<0.05 if she or he had previously visited a CAM practitioner (adjOR 3.4, had musculoskeletal pain (adjOR 1.5, had migraine (adjOR 2.3, used asthma medicines (adjOR 1.8 or suffered from another disease lasting more than three months (adjOR 2.1. Being male predicted reduced odds of visiting a CAM practitioner in the future (adjOR 0.6. CONCLUSION: We can conclude from this study that future visits to a CAM practitioner are predicted by both predisposing factors (being female, having visited a CAM practitioner previously and medical need factors (having had musculoskeletal pain, migraine, used asthma medicines or experienced another disease lasting more than three months. None of the specific variables associated with CAM visits were predictive for CAM visits four years later.

  7. A Round Trip from Medicinal Chemistry to Predictive Toxicology.

    Science.gov (United States)

    Mangiatordi, Giuseppe Felice; Carotti, Angelo; Novellino, Ettore; Nicolotti, Orazio

    2016-01-01

    Predictive toxicology is a new emerging multifaceted research field aimed at protecting human health and environment from risks posed by chemicals. Such issue is of extreme public relevance and requires a multidisciplinary approach where the experience in medicinal chemistry is of utmost importance. Herein, we will survey some basic recommendations to gather good data and then will review three recent case studies to show how strategies of ligand- and structure-based molecular design, widely applied in medicinal chemistry, can be adapted to meet the more restrictive scientific and regulatory goals of predictive toxicology. In particular, we will report: Docking-based classification models to predict the estrogenic potentials of chemicals. Predicting the bioconcentration factor using biokinetics descriptors. Modeling oral sub-chronic toxicity using a customized k-nearest neighbors (k-NN) approach. PMID:27311477

  8. Sexual abuse predicts functional somatic symptoms : An adolescent population study

    NARCIS (Netherlands)

    Bonvanie, Irma J.; van Gils, Anne; Janssens, Karin A. M.; Rosmalen, Judith G. M.

    2015-01-01

    The main aim of this study was to investigate the effect of childhood sexual abuse on medically not well explained or functional somatic symptoms (FSSs) in adolescents. We hypothesized that sexual abuse predicts higher levels of FSSs and that anxiety and depression contribute to this relationship. I

  9. Does exposure to music videos predict adolescents' sexual attitudes?

    NARCIS (Netherlands)

    Beentjes, J.W.J.; Konig, R.P.

    2013-01-01

    This study investigates whether exposure to music videos predicts adolescents' sexual attitudes when controlled for relevant characteristics of individuals and their social environment. Sexual attitudes are related to their music video use (i.e. exposure to music videos, peer group talk about music

  10. Prediction by data mining, of suicide attempts in Korean adolescents: a national study

    OpenAIRE

    Bae SM; Lee SA; Lee SH

    2015-01-01

    Sung Man Bae,1 Seung A Lee,2 Seung-Hwan Lee2,3 1Department of Counseling Psychology, The Cyber University of Korea, Seoul, South Korea; 2Clinical Emotion and Cognition Research Laboratory, Goyang, South Korea; 3Department of Psychiatry, Ilsan Paik Hospital, Inje University College of Medicine, Goyang, South Korea Objective: This study aimed to develop a prediction model for suicide attempts in Korean adolescents.Methods: We conducted a decision tree analysis of 2,754 middle and high sc...

  11. Prediction by data mining, of suicide attempts in Korean adolescents: a national study

    OpenAIRE

    Bae, Sung-Man

    2015-01-01

    Sung Man Bae,1 Seung A Lee,2 Seung-Hwan Lee2,3 1Department of Counseling Psychology, The Cyber University of Korea, Seoul, South Korea; 2Clinical Emotion and Cognition Research Laboratory, Goyang, South Korea; 3Department of Psychiatry, Ilsan Paik Hospital, Inje University College of Medicine, Goyang, South Korea Objective: This study aimed to develop a prediction model for suicide attempts in Korean adolescents.Methods: We conducted a decision tree analysis of 2,754 middle and hig...

  12. Affective decision-making predictive of Chinese adolescent drinking behaviors.

    Science.gov (United States)

    Xiao, Lin; Bechara, Antoine; Grenard, L Jerry; Stacy, W Alan; Palmer, Paula; Wei, Yonglan; Jia, Yong; Fu, Xiaolu; Johnson, C Anderson

    2009-07-01

    The goal of the current investigation was to address whether affective decision making would serve as a unique neuropsychological marker to predict drinking behaviors among adolescents. We conducted a longitudinal study of 181 Chinese adolescents in Chengdu city, China. In their 10th grade (ages 15-16), these adolescents were tested for their affective decision-making ability using the Iowa Gambling Task (IGT) and working memory capacity using the Self-Ordered Pointing Test. Self-report questionnaires were used to assess academic performance and drinking behaviors. At 1-year follow-up, questionnaires were completed to assess drinking behaviors, and the UPPS Impulsive Behavior Scale was used to examine four dimensions of impulsivity: urgency, lack of premeditation, lack of perseverance, and sensation seeking. Results indicated that those adolescents who progressed to binge drinking or exhibited consistent binge drinking not only performed poorly on the IGT but also scored significantly higher in urgency compared to those who never or occasionally drank. Moreover, better IGT scores predicted fewer drinking problems and fewer drinks 1 year later after controlling for demographic variables, the previous drinking behaviors, working memory, and impulsivity. These findings suggest that deficits in affective decision making may be important independent determinants of compulsive drinking and potentially addictive behavior in adolescents. PMID:19573273

  13. The performance of various anthropometric assessment methods for predicting low birth weight in adolescent pregnant women

    Directory of Open Access Journals (Sweden)

    Denise Cavalcante de Barros

    2014-09-01

    Full Text Available Objective: To evaluate the performance of various anthropometric evaluation methods for adolescent pregnant women in the prediction of birth weight. Methods: It is a cross-sectional study including 826 adolescent pregnant women. In the pre-pregnancy body mass index (BMI classification, the recommendations of the World Health Organization were compared with that of the Brazilian Ministry of Health and the Institute of Medicine (IOM of 1992 and 2006. The gestational weight gain adequacy was evaluated according to the classification of IOM of 1992, of 2006 and of the Brazilian Ministry of Health. The newborns were classified as low birth weight (LBW or macrosomic. Multinomial logistic regression was used for statistical analysis and sensibility, specificity, accuracy, positive and negative predictive values were calculated. Results: The evaluation, according to the Brazilian Ministry of Health, showed the best prediction for LBW among pregnant women with low weight gain (specificity = 69.5%. The evaluation according to the IOM of 1992 showed the best prediction for macrosomia among pregnant women with high weight gain (specificity = 50.0%. The adequacy of weight gain according to the IOM of 1992 classification showed the best prediction for LBW (OR = 3.84; 95%CI 2.19 - 6.74, followed by the method of the Brazilian Ministry of Health (OR = 2.88, 95%CI 1.73 - 4.79, among pregnant women with low weight gain. Conclusion: It is recommended the adoption of the Brazilian Ministry of Health proposal, associated with BMI cut-offs specific for adolescents as an anthropometric assessment method for adolescent pregnant women.

  14. Predicting Adolescent Drug Abuse: A Review of Issues, Methods and Correlates. Research Issues 11.

    Science.gov (United States)

    Lettieri, Dan J., Ed.

    Presented are 18 papers on predicting adolescent drug abuse. The papers have the following titles: "Current Issues in the Epidemiology of Drug Abuse as Related to Psychosocial Studies of Adolescent Drug Use"; "The Quest for Interpersonal Predictors of Marihuana Abuse in Adolescents"; "Assessing the Interpersonal Determinants of Adolescent Drug…

  15. Uric acid excretion predicts increased aggression in urban adolescents.

    Science.gov (United States)

    Mrug, Sylvie; Mrug, Michal

    2016-09-01

    Elevated levels of uric acid have been linked with impulsive and disinhibited behavior in clinical and community populations of adults, but no studies have examined uric acid in relation to adolescent aggression. This study examined the prospective role of uric acid in aggressive behavior among urban, low income adolescents, and whether this relationship varies by gender. A total of 84 adolescents (M age 13.36years; 50% male; 95% African American) self-reported on their physical aggression at baseline and 1.5years later. At baseline, the youth also completed a 12-h (overnight) urine collection at home which was used to measure uric acid excretion. After adjusting for baseline aggression and age, greater uric acid excretion predicted more frequent aggressive behavior at follow up, with no significant gender differences. The results suggest that lowering uric acid levels may help reduce youth aggression. PMID:27180134

  16. Attitudes and Practices of Complementary and Alternative Medicine Among Adolescents in Saudi Arabia

    OpenAIRE

    Musaiger, Abdulrahman O.; Nada A Abahussain

    2014-01-01

    The aim of this study was to investigate the attitudes and use of complementary and alternative medicine (CAM) among Saudi Arabian adolescents. A multistage stratified sampling method was used to select 736 adolescents (358 males, 378 females) aged 15–19 years from secondary schools. The study was carried out in Al-Khobar city, Eastern region of Saudi Arabia. The findings revealed that the use of CAM by adolescents in their lifetime ranged from 1.6% for acupuncture to 58.6% for honey treatmen...

  17. Sleep problems predict cortisol reactivity to stress in urban adolescents.

    Science.gov (United States)

    Mrug, Sylvie; Tyson, Anna; Turan, Bulent; Granger, Douglas A

    2016-03-01

    This study examined the role of sleep problems and sleep duration on stress-related HPA axis reactivity among urban, low income adolescents. A total of 84 adolescents (M age 13.36 years; 50% male; 95% African American) and their parents provided information on adolescents' sleep problems and sleep quantity. Adolescents completed a standardized social stress test in the laboratory (the Trier Social Stress Test; TSST). Saliva samples collected before and after the TSST yielded measures of cortisol pre-test, 15 min post-test, and 55 min post-test, as well as overall cortisol secretion and its increase (AUCG and AUCI). More sleep problems and longer sleep duration predicted higher cortisol reactivity to the TSST, particularly among females. Self-reports of sleep were more consistently related to stress-related cortisol reactivity than parent reports. Sleep problems and longer sleep duration may place adolescents at risk for HPA axis hyper-reactivity to stress, contributing to academic, behavioral and health problems. PMID:26679739

  18. Changes in the association between health complaint frequency and medicine use among adolescents in Scotland between 1998 and 2010

    DEFF Research Database (Denmark)

    Levin, Kate Ann; Whitehead, Ross; Andersen, Anette;

    2015-01-01

    OBJECTIVE: Medicines have the potential to cause harm, particularly when adolescents do not follow recommendations for use. In addition, medicine use in adolescence has been shown to track into adulthood. There is therefore a strong rationale to monitor changes in adolescent medicine use over tim...... with reductions in medicine use between 1998 and 2010. Further monitoring of medicine use is recommended, particularly the use of medicine for sleep difficulties, and for stomachache among girls....... and understand the mechanisms behind these changes METHODS: Data from the 1998, 2006 and 2010 Scotland Health Behaviour in School-aged Children Survey were modelled using multilevel logistic regression, modelling medicine use for: headache, stomachache, sleeping difficulties and nervousness, as well...... the majority of the reduction was observed between 1998 and 2006 for all five outcomes. Adjustment for health complaint frequency only explained some of this reduction. When an interaction term was added between year and health complaint frequency this was significant for boys' medicine use, suggesting...

  19. Adolescent expectations of early death predict adult risk behaviors.

    Directory of Open Access Journals (Sweden)

    Quynh C Nguyen

    Full Text Available Only a handful of public health studies have investigated expectations of early death among adolescents. Associations have been found between these expectations and risk behaviors in adolescence. However, these beliefs may not only predict worse adolescent outcomes, but worse trajectories in health with ties to negative outcomes that endure into young adulthood. The objectives of this study were to investigate perceived chances of living to age 35 (Perceived Survival Expectations, PSE as a predictor of suicidal ideation, suicide attempt and substance use in young adulthood. We examined the predictive capacity of PSE on future suicidal ideation/attempt after accounting for sociodemographics, depressive symptoms, and history of suicide among family and friends to more fully assess its unique contribution to suicide risk. We investigated the influence of PSE on legal and illegal substance use and varying levels of substance use. We utilized the National Longitudinal Study of Adolescent Health (Add Health initiated in 1994-95 among 20,745 adolescents in grades 7-12 with follow-up interviews in 1996 (Wave II, 2001-02 (Wave III and 2008 (Wave IV; ages 24-32. Compared to those who were almost certain of living to age 35, perceiving a 50-50 or less chance of living to age 35 at Waves I or III predicted suicide attempt and ideation as well as regular substance use (i.e., exceeding daily limits for moderate drinking; smoking ≥ a pack/day; and using illicit substances other than marijuana at least weekly at Wave IV. Associations between PSE and detrimental adult outcomes were particularly strong for those reporting persistently low PSE at both Waves I and III. Low PSE at Wave I or Wave III was also related to a doubling and tripling, respectively, of death rates in young adulthood. Long-term and wide-ranging ties between PSE and detrimental outcomes suggest these expectations may contribute to identifying at-risk youth.

  20. Predicting contraceptive behaviour among adolescents : social, cognitive, and contextual influences

    OpenAIRE

    2007-01-01

    Reports from Norway and other western countries show that many adolescents do not protect themselves from unintended pregnancies and sexual transmitted infections (STIs). The incidence of STIs such as chlamydia infections has increased in recent years in Norway and other European countries. The general aim of this thesis was to investigate the social, cognitive, and contextual factors that predict adolescents’ decisions about whether or not to use contraception. The study population of this t...

  1. Adolescent and young adult medicine in Australia and New Zealand: towards specialist accreditation.

    Science.gov (United States)

    Sawyer, Susan M; Farrant, Bridget; Hall, Anganette; Kennedy, Andrew; Payne, Donald; Steinbeck, Kate; Vogel, Veronica

    2016-08-01

    In Australia and New Zealand, a critical mass of academic and clinical leadership in Adolescent Medicine has helped advance models of clinical services, drive investments in teaching and training, and strengthen research capacity over the past 30 years. There is growing recognition of the importance of influencing the training of adult physicians as well as paediatricians. The Royal Australasian College of Physicians (RACP) is responsible for overseeing all aspects of specialist physician training across the two countries. Following advocacy from adolescent physicians, the RACP is advancing a three-tier strategy to build greater specialist capacity and sustain leadership in adolescent and young adult medicine (AYAM). The first tier of the strategy supports universal training in adolescent and young adult health and medicine for all basic trainees in paediatric and adult medicine through an online training resource. The second and third tiers support advanced training in AYAM for specialist practice, based on an advanced training curriculum that has been approved by the RACP. The second tier is dual training; advanced trainees can undertake 2 years training in AYAM and 2 years training in another area of specialist practice. The third tier consists of 3 years of advanced training in AYAM. The RACP is currently seeking formal recognition from the Australian Government to have AYAM accredited, a process that will be subsequently undertaken in New Zealand. The RACP is expectant that the accreditation of specialist AYAM physicians will promote sustained academic and clinical leadership in AYAM to the benefit of future generations of young Australasians. PMID:26115493

  2. Self-rated health as predictor of medicine use in adolescence

    DEFF Research Database (Denmark)

    Holstein, Bjørn Evald; Hansen, Ebba Holme; Andersen, Anette;

    2008-01-01

    PURPOSE: To examine the association between self-rated health (SRH) and medicine use for four common complaints: headache, stomach-ache, difficulties in getting to sleep and nervousness, in a nationally representative sample of adolescents. METHODS: The study population comprised of all students ...

  3. Attitudes and practices of complementary and alternative medicine among adolescents in Saudi Arabia.

    Science.gov (United States)

    Musaiger, Abdulrahman O; Abahussain, Nada A

    2015-01-01

    The aim of this study was to investigate the attitudes and use of complementary and alternative medicine (CAM) among Saudi Arabian adolescents. A multistage stratified sampling method was used to select 736 adolescents (358 males, 378 females) aged 15-19 years from secondary schools. The study was carried out in Al-Khobar city, Eastern region of Saudi Arabia. The findings revealed that the use of CAM by adolescents in their lifetime ranged from 1.6% for acupuncture to 58.6% for honey treatment, with significant differences between genders, except in the use of dietary supplements, black cumin, and acupuncture therapies. Females were more likely to use CAM for treating abdominal pains, cold and flu, and cough than males (P < 0.000). Family members and friends (67.7%) were the main source of CAM usage, followed by television (10%), and Internet (8%). Religious and medicinal herb healers were the CAM healers most commonly visited by adolescents. Nearly 21-43% of adolescents had positive attitudes toward CAM, with some significant differences between males and females. It can be concluded that CAM is widely used by Saudi adolescents, but caution should be exercised for the safe usage of some CAM treatments. CAM should not be ignored; however there is an urgent need to establish regulations for CAM usage. PMID:25560362

  4. The globalization of training in adolescent health and medicine: one size does not fit all.

    Science.gov (United States)

    Leslie, Karen

    2016-08-01

    Adolescent medicine across the globe is practiced within a variety of healthcare models, with the shared vision of the promotion of optimal health outcomes for adolescents. In the past decade, there has been a call for transformation in how health professionals are trained, with recommendations that there be adoption of a global outlook, a multiprofessional perspective and a systems approach that considers the connections between education and health systems. Many individuals and groups are now examining how best to accomplish this educational reform. There are tensions between the call for globally accepted standards of education models and practice (a one-size fits all approach) and the need to promote the ability for education practices to be interpreted and transformed to best suit local contexts. This paper discusses some of the key considerations for 'importing' training program models for adolescent health and medicine, including the importance of cultural alignment and the utilization of best evidence and practice in health professions education. PMID:26115497

  5. International survey of self-reported medicine use among adolescents

    DEFF Research Database (Denmark)

    Hansen, Ebba H; Holstein, Bjørn E; Due, Pernille;

    2003-01-01

    in the crude girl versus boy ratios for medicine use by age for all 4 symptoms. Multivariate logistic regression analyses, adjusting for age group and country, revealed the following odds ratios (95% CI) for girls' versus boys' medicine use: headache 1.56 (1.53 to 1.60), stomachache 2.16 (2.10 to 2...

  6. Subclinical bulimia predicts conduct disorder in middle adolescent girls.

    Science.gov (United States)

    Viinamäki, Anni; Marttunen, Mauri; Fröjd, Sari; Ruuska, Jaana; Kaltiala-Heino, Riittakerttu

    2013-01-01

    This study investigates the comorbidity and longitudinal associations between self-reported conduct disorder and subclinical bulimia in a community-based sample of Finnish adolescents in a 2-year prospective follow-up study. There are 2070 adolescents who participated in the survey as ninth graders (mean age 15.5) and followed-up 2 years later. The Youth Self-Report Externalizing scale was used to measure conduct disorder and DSM-IV-based questionnaire to measure bulimia. Co-occurrence of female conduct disorder and subclinical bulimia was found at ages 15 and 17. Subclinical bulimia among girls at age 15 was a risk factor for conduct disorder at age 17, but conduct disorder at age 15 was not predictive of subclinical bulimia at age 17. The pathway from bulimia to conduct disorder may be suggestive of an association with future borderline personality disorder among girls.

  7. Ética e medicina preditiva Ethics and predictive medicine

    Directory of Open Access Journals (Sweden)

    Ítalo Márcio Batista Astoni Júnior

    2010-12-01

    Full Text Available A evolução tecnológica dos tempos modernos penetrou o domínio da genética e atingiu o campo da medicina, constituindo-se na chamada medicina preditiva ou pré-sintomática. A medicina preditiva, utilizando-se de testes genéticos, é a competência prognóstica quanto à possibilidade de um indivíduo vir a desenvolver, no futuro, alguma doença ligada aos genes, objetivando prevenila e remediá-la. Entretanto, como qualquer conhecimento, a ciência do diagnóstico pré-sintomático, capaz de manipular a vida alterando a essência mesma do ser, pode produzir tanto "benefícios" quanto "malefícios", o que torna necessário problematizá-la eticamente. O presente artigo, de natureza conceitual, foi escrito almejando este fim.Technological developments in recent times have allowed us to master genetics and this has had an impact on medicine through the creation of the field of predictive or pre-symptomatic medicine. Predictive medicine, using genetic testing produces a prognosis regarding the likelihood of an individual, in the future, developing some kind of genetic disease and aims to prevent and cure it. However, as with any kind of knowledge, the science of pre-symptomatic diagnostics, which is capable of manipulating life itself, can be used for good or for ill. For this reason, there is a need to raise the ethical questions involved. This theoretical article aims to address such issues.

  8. The role of Society for Adolescent Health and Medicine in training of health professionals.

    Science.gov (United States)

    Ford, Carol A

    2016-08-01

    The Society for Adolescent Health and Medicine (SAHM) was created by health professionals committed to identifying and better addressing the health needs of adolescents and young adults, and this work has continued for nearly 50 years. The society initially focused primarily on clinical education, but has evolved to include educational activities providing clinical, research, policy, advocacy, and professional development content. Strategies have included high-quality annual meetings designed to meet the educational needs of its multi-disciplinary membership, publishing an internationally recognized journal, and developing strategic collaborations to advocate for legitimacy of the field and reform in health profession education. Historically, SAHM has been most successful at increasing specialized training in the United States among physicians, and primarily pediatricians, likely driven by the nuances of the development of adolescent medicine in this country. Successes are often linked to strategic collaborations with other professional organizations, and have been facilitated by federally funded initiatives to improve adolescent and young adult health. Recent efforts to improve professional training are focused on the use of technology, and SAHM is also currently exploring strategies to directly reach adolescents, young adults, and their parents. As the society becomes increasingly multidisciplinary and international, members have extraordinary opportunities to learn from each other, build upon lessons learned, and collaborate. Descriptions of the history of SAHM's training-focused efforts, selected highlights, and current priorities will be used to illustrate this long-standing commitment to the training of health professionals. PMID:26115503

  9. Adverse environmental exposures in pregnancy: teratology in adolescent medicine practice.

    Science.gov (United States)

    Seaver, Laurie H

    2002-06-01

    A teratogen is any drug, chemical, infectious or physical agent, or maternal disease or altered metabolic state that causes a structural or functional disability by acting on the embryo or fetus. Teratogens are responsible for approximately 10% of all human birth defects. Education of physicians caring for children and adolescents in the basic principles of teratology, the spectrum of human teratogens, and the recognition of associated anomalies is essential, because many maternal exposures and resultant fetal defects are completely preventable.

  10. Predicting Behavior Problems and Social Competence in Children of Adolescent Mothers.

    Science.gov (United States)

    Hubbs-Tait, Laura; And Others

    1994-01-01

    Describes longitudinal investigation evaluating additive model of impact of adolescent mothers' parenting practices on children. Suggests infant-mother attachment predicted behavior problems among preschool children of adolescent mothers and adolescent mothers' depression explained significant additional variance in those problems. States mothers'…

  11. Prediction of insulin resistance with anthropometric measures: lessons from a large adolescent population

    Directory of Open Access Journals (Sweden)

    Wedin WK

    2012-07-01

    Full Text Available William K Wedin,1 Lizmer Diaz-Gimenez,1 Antonio J Convit1,21Department of Psychiatry, NYU School of Medicine, New York, NY, USA; 2Nathan Kline Institute, Orangeburg, NY, USAObjective: The aim of this study was to describe the minimum number of anthropometric measures that will optimally predict insulin resistance (IR and to characterize the utility of these measures among obese and nonobese adolescents.Research design and methods: Six anthropometric measures (selected from three categories: central adiposity, weight, and body composition were measured from 1298 adolescents attending two New York City public high schools. Body composition was determined by bioelectric impedance analysis (BIA. The homeostatic model assessment of IR (HOMA-IR, based on fasting glucose and insulin concentrations, was used to estimate IR. Stepwise linear regression analyses were performed to predict HOMA-IR based on the six selected measures, while controlling for age.Results: The stepwise regression retained both waist circumference (WC and percentage of body fat (BF%. Notably, BMI was not retained. WC was a stronger predictor of HOMA-IR than BMI was. A regression model using solely WC performed best among the obese II group, while a model using solely BF% performed best among the lean group. Receiver operator characteristic curves showed the WC and BF% model to be more sensitive in detecting IR than BMI, but with less specificity.Conclusion: WC combined with BF% was the best predictor of HOMA-IR. This finding can be attributed partly to the ability of BF% to model HOMA-IR among leaner participants and to the ability of WC to model HOMA-IR among participants who are more obese. BMI was comparatively weak in predicting IR, suggesting that assessments that are more comprehensive and include body composition analysis could increase detection of IR during adolescence, especially among those who are lean, yet insulin-resistant.Keywords: BMI, bioelectrical impedance

  12. Theory of mind and switching predict prospective memory performance in adolescents.

    Science.gov (United States)

    Altgassen, Mareike; Vetter, Nora C; Phillips, Louise H; Akgün, Canan; Kliegel, Matthias

    2014-11-01

    Research indicates ongoing development of prospective memory as well as theory of mind and executive functions across late childhood and adolescence. However, so far the interplay of these processes has not been investigated. Therefore, the purpose of the current study was to investigate whether theory of mind and executive control processes (specifically updating, switching, and inhibition) predict prospective memory development across adolescence. In total, 42 adolescents and 41 young adults participated in this study. Young adults outperformed adolescents on tasks of prospective memory, theory of mind, and executive functions. Switching and theory of mind predicted prospective memory performance in adolescents.

  13. Recommendations for promoting the health and well-being of lesbian, gay, bisexual, and transgender adolescents: a position paper of the Society for Adolescent Health and Medicine.

    Science.gov (United States)

    2013-04-01

    Adolescent health care providers frequently care for patients who identify as lesbian, gay, bisexual, or transgendered (LGBT), or who may be struggling with or questioning their sexual orientation or gender identity. Whereas these youth have the same health concerns as their non-LGBT peers, LGBT teens may face additional challenges because of the complexity of the coming-out process, as well as societal discrimination and bias against sexual and gender minorities. The Society for Adolescent Health and Medicine encourages adolescent providers and researchers to incorporate the impact of these developmental processes (and understand the impacts of concurrent potential discrimination) when caring for LGBT adolescents. The Society for Adolescent Health and Medicine also encourages providers to help positively influence policy related to LGBT adolescents in schools, the foster care system, and the juvenile justice system, and within the family structure. Consistent with other medical organizations, the Society for Adolescent Health and Medicine rejects the mistaken notion that LGBT orientations are mental disorders, and opposes the use of any type of reparative therapy for LGBT adolescents.

  14. Recommendations for promoting the health and well-being of lesbian, gay, bisexual, and transgender adolescents: a position paper of the Society for Adolescent Health and Medicine.

    Science.gov (United States)

    2013-04-01

    Adolescent health care providers frequently care for patients who identify as lesbian, gay, bisexual, or transgendered (LGBT), or who may be struggling with or questioning their sexual orientation or gender identity. Whereas these youth have the same health concerns as their non-LGBT peers, LGBT teens may face additional challenges because of the complexity of the coming-out process, as well as societal discrimination and bias against sexual and gender minorities. The Society for Adolescent Health and Medicine encourages adolescent providers and researchers to incorporate the impact of these developmental processes (and understand the impacts of concurrent potential discrimination) when caring for LGBT adolescents. The Society for Adolescent Health and Medicine also encourages providers to help positively influence policy related to LGBT adolescents in schools, the foster care system, and the juvenile justice system, and within the family structure. Consistent with other medical organizations, the Society for Adolescent Health and Medicine rejects the mistaken notion that LGBT orientations are mental disorders, and opposes the use of any type of reparative therapy for LGBT adolescents. PMID:23521897

  15. Childhood Psychopathology Predicts Adolescence-Onset Offending: A Longitudinal Study

    Science.gov (United States)

    Buck, Nicole; Verhulst, Frank; van Marle, Hjalmar; van der Ende, Jan

    2013-01-01

    Moffitt, Caspi, Harrington, and Milne (2002) found in a follow-up study that many of the supposedly adolescence-limited offenders had committed offenses past adolescence. This finding raises the question of whether adulthood starts later or whether there are two distinct delinquency types, adolescence limited and adolescence onset, each with its…

  16. Investigation of adolescent accident predictive variables in hilly regions.

    Science.gov (United States)

    Mohanty, Malaya; Gupta, Ankit

    2016-09-01

    The study aims to determine the significant personal and environmental factors in predicting the adolescent accidents in the hilly regions taking into account two cities Hamirpur and Dharamshala, which lie at an average elevation of 700--1000 metres above the mean sea level (MSL). Detailed comparisons between the results of 2 cities are also studied. The results are analyzed to provide the list of most significant factors responsible for adolescent accidents. Data were collected from different schools and colleges of the city with the help of a questionnaire survey. Around 690 responses from Hamirpur and 460 responses from Dharamshala were taken for study and analysis. Standard deviations (SD) of various factors affecting accidents were calculated and factors with relatively very low SD were discarded and other variables were considered for correlations. Correlation was developed using Kendall's-tau and chi-square tests and factors those were found significant were used for modelling. They were - the victim's age, the character of road, the speed of vehicle, and the use of helmet for Hamirpur and for Dharamshala, the kind of vehicle involved was an added variable found responsible for adolescent accidents. A logistic regression was performed to know the effect of each category present in a variable on the occurrence of accidents. Though the age and the speed of vehicle were considered to be important factors for accident occurrence according to Indian accident data records, even the use of helmet comes out as a major concern. The age group of 15-18 and 18-21 years were found to be more susceptible to accidents than the higher age groups. Due to the presence of hilly area, the character of road becomes a major concern for cause of accidents and the topography of the area makes the kind of vehicle involved as a major variable for determining the severity of accidents. PMID:26077876

  17. [Children's and adolescent's use of medicine for aches and psychological problems: secular trends from 1988 to 2006.

    DEFF Research Database (Denmark)

    Holstein, Bjørn; Andersen, Anette; Due, Pernille;

    2009-01-01

    INTRODUCTION: Medicine use for aches and psychological problems is common among adolescents. Medicines are toxic and may have harmful side effects. It is therefore important to study change over time and patterns of medicine use. The objective of this paper is to describe self-reported medicine use......: There was a significant increase in 11-, 13-, and 15-year-old student's use of medicine for aches and psychological problems from 1988 to 2006. In the same period, there was a decrease in the prevalence of students who reported pains monthly. Udgivelsesdato: 2009-Jan-5...

  18. Predicting adolescent's cyberbullying behavior: A longitudinal risk analysis.

    Science.gov (United States)

    Barlett, Christopher P

    2015-06-01

    The current study used the risk factor approach to test the unique and combined influence of several possible risk factors for cyberbullying attitudes and behavior using a four-wave longitudinal design with an adolescent US sample. Participants (N = 96; average age = 15.50 years) completed measures of cyberbullying attitudes, perceptions of anonymity, cyberbullying behavior, and demographics four times throughout the academic school year. Several logistic regression equations were used to test the contribution of these possible risk factors. Results showed that (a) cyberbullying attitudes and previous cyberbullying behavior were important unique risk factors for later cyberbullying behavior, (b) anonymity and previous cyberbullying behavior were valid risk factors for later cyberbullying attitudes, and (c) the likelihood of engaging in later cyberbullying behavior increased with the addition of risk factors. Overall, results show the unique and combined influence of such risk factors for predicting later cyberbullying behavior. Results are discussed in terms of theory.

  19. Weaker Self-Esteem in Adolescence Predicts Smoking

    OpenAIRE

    Saari, Antti J; Jukka Kentala; Mattila, Kari J

    2015-01-01

    Background. To study whether weaker self-esteem in adolescence is connected with smoking behavior in adulthood. Methods. An age cohort born in 1979 responded to the Lawrence Self-Esteem Questionnaire (LAWSEQ) at the age of 16 (n = 1,072). Respondents' smoking behavior was monitored annually during adolescence and 75.3% (n = 813) of them remained nonsmokers during adolescence. A follow-up questionnaire eliciting smoking behavior was sent to the adolescent nonsmokers at the age of 29 years. Res...

  20. School Mobility during Childhood Predicts Psychotic Symptoms in Late Adolescence

    Science.gov (United States)

    Winsper, Catherine; Wolke, Dieter; Bryson, Alex; Thompson, Andrew; Singh, Swaran P.

    2016-01-01

    Background: Recently, school mobility was identified as a risk factor for psychotic symptoms in early adolescence. The extent to which this risk continues into late adolescence and the trajectories via which this risk manifests remain unexplored. Methods: Psychotic symptoms in 4,720 adolescents aged 18 were ascertained by trained psychologists…

  1. Stability of executive function and predictions to adaptive behavior from middle childhood to pre-adolescence

    OpenAIRE

    Madeline eHarms; Vivian eZayas; Andrew eMeltzoff; Stephanie eCarlson

    2014-01-01

    The shift from childhood to adolescence is characterized by rapid remodeling of the brain and increased risk-taking behaviors. Current theories hypothesize that developmental enhancements in sensitivity to affective environmental cues in adolescence may undermine executive function (EF) and increase the likelihood of problematic behaviors. In the current study, we examined the extent to which EF in childhood predicts EF in early adolescence. We also tested whether individual differences in ne...

  2. Phylogenies reveal predictive power of traditional medicine in bioprospecting

    DEFF Research Database (Denmark)

    Saslis-Lagoudakis, C Haris; Savolainen, Vincent; Williamson, Elizabeth M;

    2012-01-01

    There is controversy about whether traditional medicine can guide drug discovery, and investment in bioprospecting informed by ethnobotanical data has fluctuated. One view is that traditionally used medicinal plants are not necessarily efficacious and there are no robust methods for distinguishing...... phylogenetic methods from community ecology, we reveal significant clustering of the 1,500 traditionally used species, and provide a direct measure of the relatedness of the three medicinal floras. We demonstrate shared phylogenetic patterns across the floras: related plants from these regions are used...

  3. Adolescents' Implicit Theories Predict Desire for Vengeance after Peer Conflicts: Correlational and Experimental Evidence

    Science.gov (United States)

    Yeager, David S.; Trzesniewski, Kali H.; Tirri, Kirsi; Nokelainen, Petri; Dweck, Carol S.

    2011-01-01

    Why do some adolescents respond to interpersonal conflicts vengefully, whereas others seek more positive solutions? Three studies investigated the role of implicit theories of personality in predicting violent or vengeful responses to peer conflicts among adolescents in Grades 9 and 10. They showed that a greater belief that traits are fixed (an…

  4. Loneliness of Indonesian and Chinese Adolescents as Predicted by Relationships with Friends and Parents

    Science.gov (United States)

    Liu, Junsheng; Li, Dan; Purwono, Urip; Chen, Xinyin; French, Doran C.

    2015-01-01

    This study explored the extent to which loneliness of Indonesian and Chinese adolescents was predicted by their intimacy and conflict with friends and parents. The total sample included 1,833 thirteen- and fifteen-year-old adolescents recruited from urban schools. Boys reported more loneliness than girls, and Chinese boys reported more loneliness…

  5. Prenatal stress due to a natural disaster predicts insulin secretion in adolescence

    OpenAIRE

    Kelsey N. Dancause; Veru, Franz; Andersen, Ross E.; Laplante, David P.; King, Suzanne

    2013-01-01

    Prenatal stress might increase cardiometabolic disease risk. We measured prenatal stress due to an ice storm in 1998, and measured glucose tolerance among a subsample of 32 exposed adolescents in 2011. Severity of stress was positively associated with insulin secretion, suggesting that prenatal stress independently predicts metabolic outcomes in adolescence.

  6. Evolutionary prediction of medicinal properties in the genus Euphorbia L

    DEFF Research Database (Denmark)

    Ernst, Madeleine; Saslis Lagoudakis, Haris; Grace, Olwen M;

    2016-01-01

    associated to systems of the human body and only poorly reflect biological responses to the treatment. Here we show that medicinal plant uses interpreted from a perspective of a biological response can reveal different phylogenetic patterns of presumed underlying bioactivity compared to standardised methods...... of medicinal plant use classification. In the cosmopolitan and pharmaceutically highly relevant genus Euphorbia L., identifying plant uses modulating the inflammatory response highlighted a greater phylogenetic diversity and number of potentially promising species than standardised categories. Our...

  7. Delay Discounting Predicts Adolescent Substance Abuse Treatment Outcome

    OpenAIRE

    Stanger, Catherine; Ryan, Stacy R.; Fu, Hongyun; Landes, Reid D.; Jones, Bryan A.; Bickel, Warren K.; Budney, Alan J.

    2011-01-01

    The purpose of the current study was to identify predictors of delay discounting among adolescents receiving treatment for marijuana abuse or dependence, and to test delay discounting as a predictor of treatment outcome. Participants for this study were 165 adolescents (88% male) between the ages of 12 and 18 (M =15.8; SD = 1.3) who enrolled in a clinical trial comparing three behavioral treatments for adolescent marijuana abuse or dependence. Participants completed a delay discounting task a...

  8. Predicting Aggression among Male Adolescents: an Application of the Theory of Planned Behavior

    OpenAIRE

    ZinatMotlagh, Fazel; Ataee, Mari; Jalilian, Farzad; MirzaeiAlavijeh, Mehdi; Aghaei, Abbas; Karimzadeh Shirazi, Kambiz

    2013-01-01

    Background: Aggressive behaviorin adolescencecan be expressed asa predictorfor crime, substanceabuse, depression and academic failure. The purpose of this study was to determine the prediction of aggression among Iranian adolescent based on theory of planned behavior (TPB) as a theoretical framework.

  9. Psychopathology in adolescents and young adults : prediction, course and prevalence

    NARCIS (Netherlands)

    R.F. Ferdinand (Robert)

    1995-01-01

    textabstractThis manuscript contains results of an epidemiological study of psychopathology in adolescents and young adults. The first aim of the study was to determine the development of psychopathology from adolescence into young adulthood. The second aim was to validate recently developed' proced

  10. Factors Predicting Rural Chinese Adolescents' Anxieties, Fears and Depression

    Science.gov (United States)

    Li, Huijun; Zhang, Ying

    2008-01-01

    This study examined age, gender, birth order and self-perceived level of achievement and popularity, as predictors of anxieties, fears and depression in Chinese adolescents. A sample of 398 rural Chinese adolescents participated in this study. Gender, academic performance and popularity have been found to make the greatest contributions to the…

  11. Do clinical prediction models improve concordance of treatment decisions in reproductive medicine?

    NARCIS (Netherlands)

    J.W. van der Steeg; P. Steures; M.J.C. Eijkemans; J.D.F. Habbema; P.M.M. Bossuyt; P.G.A. Hompes; F. van der Veen; B.W.J. Mol

    2006-01-01

    Objective To assess whether the use of clinical prediction models improves concordance between gynaecologists with respect to treatment decisions in reproductive medicine. Design We constructed 16 vignettes of subfertile couples by varying fertility history, postcoital test, sperm motility, follicle

  12. A nomogram to predict the probability of passing the American Board of Internal Medicine examination

    OpenAIRE

    Brateanu, Andrei; Yu, Changhong; Michael W Kattan; Olender, Jeff; Nielsen, Craig

    2012-01-01

    Background: Although the American Board of Internal Medicine (ABIM) certification is valued as a reflection of physicians’ experience, education, and expertise, limited methods exist to predict performance in the examination. Purpose: The objective of this study was to develop and validate a predictive tool based on variables common to all residency programs, regarding the probability of an internal medicine graduate passing the ABIM certification examination. Methods: The development cohort ...

  13. Predicting Bullying: Exploring the Contributions of Childhood Negative Life Experiences in Predicting Adolescent Bullying Behavior.

    Science.gov (United States)

    Connell, Nadine M; Morris, Robert G; Piquero, Alex R

    2016-07-01

    Although there has been much interest in research on aggression and in particular bullying, a relatively less charted area of research has centered on articulating a better understanding of the mechanisms and processes by which persons are at increased risk for bullying. Furthermore, those studies that have investigated the linkages between childhood experiences and bullying perpetration have been limited with respect to definitional and operational issues, reliance on cross-sectional data, and the lack of assessing competing explanations of bullying perpetration. Using five waves of data from a community-based longitudinal sample of children followed through age 18 (N = 763), the current study examines the extent to which childhood negative life events in a variety of domains predict adolescent bullying. Results show that early childhood experiences, particularly those within the family and school domains, may alter life trajectories and can act as predictors for later adolescent bullying, thereby underscoring the potential importance that relatively minor experiences can have over the long term. Implications for future research based on these analyses are examined. PMID:25759430

  14. Prediction of Log "P": ALOGPS Application in Medicinal Chemistry Education

    Science.gov (United States)

    Kujawski, Jacek; Bernard, Marek K.; Janusz, Anna; Kuzma, Weronika

    2012-01-01

    Molecular hydrophobicity (lipophilicity), usually quantified as log "P" where "P" is the partition coefficient, is an important molecular characteristic in medicinal chemistry and drug design. The log "P" coefficient is one of the principal parameters for the estimation of lipophilicity of chemical compounds and pharmacokinetic properties. The…

  15. General Report & Recommendations in Predictive, Preventive and Personalised Medicine 2012: White Paper of the European Association of Predictive, Preventive and Personalised Medicine

    Directory of Open Access Journals (Sweden)

    Golubnitschaja Olga

    2012-11-01

    Full Text Available Abstract This report is the collective product of word-leading experts working in the branches of integrative medicine by predictive, preventive and personalised medicine (PPPM under the coordination of the European Association for Predictive, Preventive and Personalised Medicine. The general report has been prepared as the consortium document proposed at the EPMA World Congress 2011 which took place in Bonn, Germany. This forum analyzed the overall deficits and trends relevant for the top-science and daily practice in PPPM focused on the patient. Follow-up consultations resulted in a package of recommendations for consideration by research units, educators, healthcare industry, policy-makers, and funding bodies to cover the current knowledge deficit in the field and to introduce integrative approaches for advanced diagnostics, targeted prevention, treatments tailored to the person and cost-effective healthcare.

  16. Weaker Self-Esteem in Adolescence Predicts Smoking

    Directory of Open Access Journals (Sweden)

    Antti J. Saari

    2015-01-01

    Full Text Available Background. To study whether weaker self-esteem in adolescence is connected with smoking behavior in adulthood. Methods. An age cohort born in 1979 responded to the Lawrence Self-Esteem Questionnaire (LAWSEQ at the age of 16 n=1,072. Respondents’ smoking behavior was monitored annually during adolescence and 75.3% n=813 of them remained nonsmokers during adolescence. A follow-up questionnaire eliciting smoking behavior was sent to the adolescent nonsmokers at the age of 29 years. Response rate at follow-up was 46.2% n=376. Results. Weaker self-esteem (LAWSEQ score ≥ 3 during the adolescence was not significantly associated with smoking in adulthood. However, those respondents who had weaker self-esteem in adolescence had increased risk of having been smoking regularly (adjusted OR 1.8, 95% CI 1.1–3.0 although not all of them were smokers at the time of the follow-up. Conclusions. Those with weaker self-esteem in adolescence are more likely to smoke regularly in adulthood.

  17. To Set Up a Logistic Regression Prediction Model for Hepatotoxicity of Chinese Herbal Medicines Based on Traditional Chinese Medicine Theory.

    Science.gov (United States)

    Liu, Hongjie; Li, Tianhao; Chen, Lingxiu; Zhan, Sha; Pan, Meilan; Ma, Zhiguo; Li, Chenghua; Zhang, Zhe

    2016-01-01

    Aims. To establish a logistic regression (LR) prediction model for hepatotoxicity of Chinese herbal medicines (HMs) based on traditional Chinese medicine (TCM) theory and to provide a statistical basis for predicting hepatotoxicity of HMs. Methods. The correlations of hepatotoxic and nonhepatotoxic Chinese HMs with four properties, five flavors, and channel tropism were analyzed with chi-square test for two-way unordered categorical data. LR prediction model was established and the accuracy of the prediction by this model was evaluated. Results. The hepatotoxic and nonhepatotoxic Chinese HMs were related with four properties (p 0.05). There were totally 12 variables from four properties and five flavors for the LR. Four variables, warm and neutral of the four properties and pungent and salty of five flavors, were selected to establish the LR prediction model, with the cutoff value being 0.204. Conclusions. Warm and neutral of the four properties and pungent and salty of five flavors were the variables to affect the hepatotoxicity. Based on such results, the established LR prediction model had some predictive power for hepatotoxicity of Chinese HMs.

  18. Parental Alcohol Involvement and Adolescent Alcohol Expectancies Predict Alcohol Involvement in Male Adolescents

    OpenAIRE

    Cranford, James A.; Zucker, Robert A.; Jester, Jennifer M.; Puttler, Leon I.; Fitzgerald, Hiram E.

    2010-01-01

    Current models of adolescent drinking behavior hypothesize that alcohol expectancies mediate the effects of other proximal and distal risk factors. This longitudinal study tested the hypothesis that the effects of parental alcohol involvement on their children’s drinking behavior in mid-adolescence are mediated by the children’s alcohol expectancies in early adolescence. A sample of 148 initially 9–11 year old boys and their parents from a high-risk population and a contrast group of communit...

  19. Predictive data mining in clinical medicine: Current issues and guidelines

    OpenAIRE

    Bellazzi, Riccado; Zupan, Blaz

    2008-01-01

    BACKGROUND: The widespread availability of new computational methods and tools for data analysis and predictive modeling requires medical informatics researchers and practitioners to systematically select the most appropriate strategy to cope with clinical prediction problems. In particular, the collection of methods known as 'data mining' offers methodological and technical solutions to deal with the analysis of medical data and construction of prediction models. A large variety of these met...

  20. Observed Measures of Negative Parenting Predict Brain Development during Adolescence

    OpenAIRE

    Sarah Whittle; Nandita Vijayakumar; Meg Dennison; Orli Schwartz; Simmons, Julian G.; Lisa Sheeber; Allen, Nicholas B.

    2016-01-01

    Limited attention has been directed toward the influence of non-abusive parenting behaviour on brain structure in adolescents. It has been suggested that environmental influences during this period are likely to impact the way that the brain develops over time. The aim of this study was to investigate the association between aggressive and positive parenting behaviors on brain development from early to late adolescence, and in turn, psychological and academic functioning during late adolescen...

  1. Predictive factors of alcohol and tobacco use in adolescents

    OpenAIRE

    Alicia Alvarez-Aguirre; María Magdalena Alonso-Castillo; Ana Carolina Guidorizzi Zanetti

    2014-01-01

    OBJECTIVES: to analyze the effect of self-esteem, assertiveness, self-efficacy and resiliency on alcohol and tobacco consumption in adolescents. METHOD: a descriptive and correlational study was undertaken with 575 adolescents in 2010. The Self-Esteem Scale, the Situational Confidence Scale, the Assertiveness Questionnaire and the Resiliency Scale were used. RESULTS: the adjustment of the logistic regression model, considering age, sex, self-esteem, assertiveness, self-efficacy and resiliency...

  2. School-Based Health Center Model Within the Military Health System: The Role of the Adolescent Medicine Physician.

    Science.gov (United States)

    Greene, Jeffery P; Dawson, Rachel

    2016-09-01

    Adolescents are less motivated to seek medical care for various reasons. Within the military health care system, access barriers, although less encountered, can still be a burden not only to the adolescent, but also the school system. This article describes the development of a school-based health center within a school district on a military installation. The school clinic was created by adolescent medicine specialists to maximize access to care. Students of adolescent age utilized the clinic for evaluation of acute and chronic conditions, preventative services, preparticipation evaluation, and other general complaints. After receiving signed consent forms, 30% of students were eligible for health care. There was minimal cost to initiate the service. Development of school-based health center programs at other military installations could potentially improve the status of the military health system during a time of high stress among military dependents. PMID:27612351

  3. Prescribing patterns of medicine classified as 'antidepressants' in South African children and adolescents

    Directory of Open Access Journals (Sweden)

    Jan H. P. Serfontein

    2009-04-01

    Full Text Available

    The main objective of this study was to characterise prescribing patterns of medicine classified as 'antidepressants' (hereafter simply referred to as antidepressants in children and adolescents in the private health care sector of South Africa. A retrospective drug utilisation design was used to identify patients aged 19 years and younger from a South African pharmaceutical benefit management company’s database, whom were issued at least one antidepressant between 1 January 2006 and 31 December 2006. Prescribed daily dosages (PDDs were calculated using the Statistical Analysis System® program. A total of 1 013 patients received a mean number of 2.88 (SD 3.04 prescriptions per patient. Females received more prescriptions than their male counterparts, with the highest prevalence in the 15 ≤ 19 years age group. The pharmacological groups most prescribed were the selective serotonin reuptake inhibitors (43.0% and the tricyclics (42.7%, with imipramine (22.04% and amitriptyline (19% as the most commonly prescribed drugs. Approximately 30% (n = 2 300 of all antidepressants in the study population were prescribed off-label. Amitriptyline and clomipramine were prescribed at daily dosages higher than recommended in children and adolescents aged 9 ≤ 15 years. Lithium, trimipramine, trazodone and sulpiride were prescribed at sub-therapeutic dosages in adolescents. This study provided insight in the prescribing patterns of medicine classified as antidepressants in South African children and adolescents. These drugs, however, have many indications. Further research is needed to determine reasons why specific drugs are prescribed in this population.

    Opsomming

    Die algemene doelstelling van hierdie studie was om die voorskrifpatrone van middels wat as 'antidepressante' geklassifiseer word (hierna verwys na as slegs antidepressante wat vir kinders en adolessente in die Suid-Afrikaanse private gesondheidsorgsektor

  4. Training international medical graduate clinical fellows: the challenges and opportunities for adolescent medicine programs.

    Science.gov (United States)

    Goldberg, Eudice

    2016-08-01

    Adolescent medicine achieved accreditation status first in the United States in 1994 and then in Canada in 2008 and even if it is not an accredited subspecialty in most other Western nations, it has still become firmly established as a distinct discipline. This has not necessarily been the case in some developing countries, where even the recognition of adolescence as a unique stage of human development is not always acknowledged. The program at SickKids in Toronto has prided itself in treating its international medical graduates (IMG) clinical fellows the same as their Canadian subspecialty residents by integrating them seamlessly into the training program. Although this approach has been laudable to a great extent, it may have fallen short in formally acknowledging and addressing the challenges that the IMG trainees have had to overcome. Moving forward, faculty must be trained and supports instituted that are geared specifically towards these challenges. This must be done on a formal basis to ensure both the success of the trainees as well as the overall enrichment of the fellowship training programs. PMID:26115499

  5. Predicting adolescent perpetration in cyberbullying: an application of the theory of planned behavior.

    Science.gov (United States)

    Heirman, Wannes; Walrave, Michel

    2012-11-01

    This study aims to contribute to the research field on cyberbullying by offering a comprehensive theoretical framework that helps to predict adolescents' perpetration of cyberbullying. One thousand forty-two pupils from 12 to 18 years old in 30 different Belgian secondary schools participated in two surveys within a three-month interval. Structural equation modeling was used to test whether the overall model of theory of planned behavior (TPB) helps to predict adolescents' self-reported perpetration in cyberbullying. Overall, the present study provides strong support for the theoretical utility of the TPB in cyberbullying research. The model accounted for 44.8% of the variance in adolescents' behavioral intention to cyberbully and 33.2% of the variance in self-reported cyberbullying perpetration. We found a strong positive relationship between adolescents' attitude towards cyberbullying and their behavioral intention to perpetrate it. Perceived behavioral control and subjective norm, the other two TPB-constructs, were also significant albeit relatively less important predictors of adolescents' intention to cyberbully. The finding that adolescents' attitude is the most important predictor of perpetration, entails that prevention and intervention strategies should aim at reducing the perceived acceptability of cyberbullying among adolescents by converting neutral or positive attitudes towards this anti-social behavior into negative evaluations.

  6. Predicting adolescent perpetration in cyberbullying: an application of the theory of planned behavior.

    Science.gov (United States)

    Heirman, Wannes; Walrave, Michel

    2012-11-01

    This study aims to contribute to the research field on cyberbullying by offering a comprehensive theoretical framework that helps to predict adolescents' perpetration of cyberbullying. One thousand forty-two pupils from 12 to 18 years old in 30 different Belgian secondary schools participated in two surveys within a three-month interval. Structural equation modeling was used to test whether the overall model of theory of planned behavior (TPB) helps to predict adolescents' self-reported perpetration in cyberbullying. Overall, the present study provides strong support for the theoretical utility of the TPB in cyberbullying research. The model accounted for 44.8% of the variance in adolescents' behavioral intention to cyberbully and 33.2% of the variance in self-reported cyberbullying perpetration. We found a strong positive relationship between adolescents' attitude towards cyberbullying and their behavioral intention to perpetrate it. Perceived behavioral control and subjective norm, the other two TPB-constructs, were also significant albeit relatively less important predictors of adolescents' intention to cyberbully. The finding that adolescents' attitude is the most important predictor of perpetration, entails that prevention and intervention strategies should aim at reducing the perceived acceptability of cyberbullying among adolescents by converting neutral or positive attitudes towards this anti-social behavior into negative evaluations. PMID:23079360

  7. Predicting Adolescent Drug Abuse Treatment Outcome with the Personal Experience Inventory (PEI)

    Science.gov (United States)

    Stinchfield, Randy; Winters, Ken C.

    2004-01-01

    The purposes of this study were to examine the clinical utility of the Personal Experience Inventory (PEI) Psychosocial scales to predict adolescent drug abuse treatment outcome. The role of psychosocial risk factors in predicting treatment outcome also has theoretical interest given that such factors have been associated with the development of…

  8. Body Dissatisfaction Prospectively Predicts Depressive Mood and Low Self-Esteem in Adolescent Girls and Boys

    Science.gov (United States)

    Paxton, Susan J.; Neumark-Sztainer, Dianne; Hannan, Peter J.; Eisenberg, Marla E.

    2006-01-01

    This research examined whether body dissatisfaction prospectively predicted depressive mood and low self-esteem in adolescent girls and boys 5 years later. Participants were early-adolescent girls (n = 440, Time 1 M age = 12.7 years) and boys (n = 366, Time 1 M age = 12.8 years) and midadolescent girls (n = 946, Time 1 M age = 15.8 years) and boys…

  9. Sensation seeking predicting growth in adolescent problem behaviors.

    Science.gov (United States)

    Byck, Gayle R; Swann, Gregory; Schalet, Benjamin; Bolland, John; Mustanski, Brian

    2015-06-01

    There is limited literature on the relationship between sensation seeking and adolescent risk behaviors, particularly among African Americans. We tested the association between psychometrically-derived subscales of the Zuckerman Sensation Seeking Scale and the intercepts and slopes of individual growth curves of conduct problems, sexual risk taking, and substance use from ages 13 to 18 years by sex. Boys and girls had different associations between sensation seeking and baseline levels and growth of risk behaviors. The Pleasure Seeking scale was associated with baseline levels of conduct problems in boys and girls, baseline substance use in boys, and growth in sexual risk taking and substance use by girls. Girls had the same pattern of associations with the Danger/Novelty scale as the Pleasure Seeking scale. Knowledge about the relationships between adolescent risk taking and sensation seeking can help in the targeted design of prevention and intervention programs for the understudied population of very low-income, African American adolescents. PMID:25112599

  10. Does positive youth development predict adolescent attitudes about sexuality?

    Science.gov (United States)

    Chapman, Erin N; Werner-Wilson, Ronald Jay

    2008-01-01

    The purpose of this study was to explore the relationships among individual factors, parental factors, involvement in activities, and adolescent attitudes regarding sex (the outcome variable). We suggest that Positive Youth Development (PYD) research and programming should include promoting healthy sexuality as an important developmental outcome for youth. PYD philosophy and theory, bioecological theory (Bronfenbrenner & Morris, 1998), and identity development theory (Erikson, 1983, 1968; Marcia, 1980, 1993) provided the foundation for this study and were used to make the connections between PYD, adolescent sexuality (including attitudes and behavior), and aspects of the parent-adolescent relationship. Both self-esteem and sexual experience were significant predictors of attitudes regarding sex, but overall, parents contributed the most influence on the outcome variable. (It should be noted, however, that parental influence was the only factor that was a significant predictor.) Only one of the two involvements in activities variables was a significant predictor of attitudes regarding sex.

  11. Back to the Roots: Prediction of Biologically Active Natural Products from Ayurveda Traditional Medicine

    DEFF Research Database (Denmark)

    Polur, Honey; Joshi, Tejal; Workman, Christopher;

    2011-01-01

    . We hereby present a number of examples where the traditional medicinal use of the plant matches with the medicinal use of the drug that is structurally similar to a plant component. With this approach, we have brought to light a number of obscure compounds of natural origin (e.g. kanugin......Ayurveda, the traditional Indian medicine is one of the most ancient, yet living medicinal traditions. In the present work, we developed an in silico library of natural products from Ayurveda medicine, coupled with structural information, plant origin and traditional therapeutic use. Following this......, we compared their structures with those of drugs from DrugBank and we constructed a structural similarity network. Information on the traditional therapeutic use of the plants was integrated in the network in order to provide further evidence for the predicted biologically active natural compounds...

  12. Examining a social reaction model in the prediction of adolescent alcohol use.

    Science.gov (United States)

    Litt, Dana M; Lewis, Melissa A

    2016-09-01

    The prototype willingness model (PWM; Gerrard et al., 2008) is a modified dual-processing model designed to improve the predictive value of existing health risk behavior by suggesting that there are two pathways to health risk behaviors: a reasoned path that is mediated by behavioral intention and a social reaction path that is mediated by behavioral willingness. Although there is evidence supporting the social reaction path to risk behavior among adolescents, most of this work has focused on specific components of the pathway such as prototypes or willingness rather than looking at the entire social reaction pathway as a whole. As such, the primary goal of the present study was to determine whether the social reaction pathway has acceptable fit for a sample of adolescents using a longitudinal design. Results from 835 adolescents support the social reaction pathway of the PWM model when applied to adolescent alcohol use. Specifically, prototypes, perceived vulnerability, and norms predicted willingness to drink, which in turn predicted drinking behavior (drinks per week and peak number of drinks) over a period of 12months. As such, these findings suggest that the social reaction pathway of the PWM is applicable to adolescent drinkers, meaning that adolescent drinking behavior is based on a less planned and socially based decision process. PMID:27155242

  13. Predicting a Longitudinal Guttman Simplex of Adolescent Substance Use.

    Science.gov (United States)

    McGuigan, Kimberly A.; And Others

    The longitudinal Guttman simplex (LGS), a method of modeling stage sequences or levels over time, allows for individual differences in sequence progression or development. The LGS is particularly appropriate in modeling tobacco, alcohol, and marijuana use stages with adolescent subjects where relationships among drugs and degree of involvement may…

  14. Predicting Intentions to Perform Protective Sexual Behaviours among Norwegian Adolescents

    Science.gov (United States)

    Myklestad, Ingri; Rise, Jostein

    2008-01-01

    This paper examines the socio-cognitive processes underlying intentions to use condoms and contraceptive pills, using the Theory of Planned Behaviour extended with prototypes in a group of young Norwegian adolescents. The data are derived from a questionnaire survey comprising all pupils in Grade Nine at three schools in Oslo (n = 196). Using…

  15. Pituitary Volume Prospectively Predicts Internalizing Symptoms in Adolescence

    Science.gov (United States)

    Zipursky, Amy R.; Whittle, Sarah; Yucel, Murat; Lorenzetti, Valentina; Wood, Stephen J.; Lubman, Dan I.; Simmons, Julian G.; Allen, Nicholas B.

    2011-01-01

    Background: Early adolescence is a critical time for the development of both internalizing and externalizing disorders. We aimed to investigate whether pituitary volume, an index of hypothalamic-pituitary-adrenal (HPA) axis function, represents a vulnerability factor for the emergence of internalizing and externalizing symptoms during adolescence…

  16. Prediction by data mining, of suicide attempts in Korean adolescents: a national study

    Directory of Open Access Journals (Sweden)

    Bae SM

    2015-09-01

    Full Text Available Sung Man Bae,1 Seung A Lee,2 Seung-Hwan Lee2,3 1Department of Counseling Psychology, The Cyber University of Korea, Seoul, South Korea; 2Clinical Emotion and Cognition Research Laboratory, Goyang, South Korea; 3Department of Psychiatry, Ilsan Paik Hospital, Inje University College of Medicine, Goyang, South Korea Objective: This study aimed to develop a prediction model for suicide attempts in Korean adolescents.Methods: We conducted a decision tree analysis of 2,754 middle and high school students nationwide. We fixed suicide attempt as the dependent variable and eleven sociodemographic, intrapersonal, and extrapersonal variables as independent variables.Results: The rate of suicide attempts of the total sample was 9.5%, and severity of depression was the strongest variable to predict suicide attempt. The rates of suicide attempts in the depression and potential depression groups were 5.4 and 2.8 times higher than that of the non-depression group. In the depression group, the most powerful factor to predict a suicide attempt was delinquency, and the rate of suicide attempts in those in the depression group with higher delinquency was two times higher than in those in the depression group with lower delinquency. Of special note, the rate of suicide attempts in the depressed females with higher delinquency was the highest. Interestingly, in the potential depression group, the most impactful factor to predict a suicide attempt was intimacy with family, and the rate of suicide attempts of those in the potential depression group with lower intimacy with family was 2.4 times higher than that of those in the potential depression group with higher intimacy with family. And, among the potential depression group, middle school students with lower intimacy with family had a 2.5-times higher rate of suicide attempts than high school students with lower intimacy with family. Finally, in the non-depression group, stress level was the most powerful factor to

  17. Is victimization from bullying associated with medicine use among adolescents? A nationally representative cross-sectional survey in Denmark

    DEFF Research Database (Denmark)

    Due, Pernille; Hansen, Ebba Holme; Merlo, Juan;

    2007-01-01

    OBJECTIVE: The goal was to examine whether being a victim of bullying was associated with medicine use, taking into account the increased prevalence of physical and psychological symptoms. METHODS: The study population included all students in grades 5, 7, and 9 (mean ages: 11.6, 13.6, and 15.......6 years, respectively) in a random sample of schools in Denmark (participation rate: 88.5%; N = 5205). The students reported health problems, medicine use, bullying, and a range of psychosocial conditions in an anonymous standardized questionnaire. The outcome measure was self-reported medicine use...... for headache, stomachache, difficulties in getting to sleep, and nervousness. The determinant was frequency of exposure to bullying, measured with 1 item. RESULTS: In multivariate models adjusted for age and social class, we found that adolescent victims of bullying used medicine for pains and psychological...

  18. Perceived parenting behaviours predict young adolescents' nutritional intake and body fatness.

    Science.gov (United States)

    Kim, Mi-Jeong; McIntosh, William A; Anding, Jenna; Kubena, Karen S; Reed, Debra B; Moon, Gap-Soon

    2008-10-01

    This study investigated whether perceptions of parenting behaviours predict young adolescents' nutritional intake and body fatness. The randomly selected study sample consisted of 106 13-15 years olds from Houston Metropolitan Statistical Area. Parenting style variables were created by cluster analysis and factor analysis. A two-cluster solution for both maternal and paternal parenting style represented authoritative vs. non-authoritative parenting. Two parenting dimension factors derived were maternal/paternal nurturing and control. For adolescents' energy and nutrient intake, greater maternal nurturing appeared to be most beneficial given its association with lower consumption of total kilocalorie and lower saturated fat intake. Paternal nurturing was associated with lower sodium intake, whereas paternal control predicted lower percentage of kilocalories from carbohydrate and percentage Dietary Reference Intake for dietary fibre, and greater percentage of kilocalories from total fat. Maternal authoritative parenting and lower maternal control over their adolescents may have protective effects against having heavier and fatter adolescents given their associations with adolescents' body weight, sub-scapular skinfold, waist circumference, body mass index, and the tendencies of being at risk of overweight and being overweight. None of paternal parenting styles or dimensions appeared to be significantly related to adolescents' body fatness. PMID:18811793

  19. Perceived parenting behaviours predict young adolescents' nutritional intake and body fatness.

    Science.gov (United States)

    Kim, Mi-Jeong; McIntosh, William A; Anding, Jenna; Kubena, Karen S; Reed, Debra B; Moon, Gap-Soon

    2008-10-01

    This study investigated whether perceptions of parenting behaviours predict young adolescents' nutritional intake and body fatness. The randomly selected study sample consisted of 106 13-15 years olds from Houston Metropolitan Statistical Area. Parenting style variables were created by cluster analysis and factor analysis. A two-cluster solution for both maternal and paternal parenting style represented authoritative vs. non-authoritative parenting. Two parenting dimension factors derived were maternal/paternal nurturing and control. For adolescents' energy and nutrient intake, greater maternal nurturing appeared to be most beneficial given its association with lower consumption of total kilocalorie and lower saturated fat intake. Paternal nurturing was associated with lower sodium intake, whereas paternal control predicted lower percentage of kilocalories from carbohydrate and percentage Dietary Reference Intake for dietary fibre, and greater percentage of kilocalories from total fat. Maternal authoritative parenting and lower maternal control over their adolescents may have protective effects against having heavier and fatter adolescents given their associations with adolescents' body weight, sub-scapular skinfold, waist circumference, body mass index, and the tendencies of being at risk of overweight and being overweight. None of paternal parenting styles or dimensions appeared to be significantly related to adolescents' body fatness.

  20. Prediction of adolescent and adult adiposity outcomes from early life anthropometrics

    DEFF Research Database (Denmark)

    Graversen, Lise; Sørensen, Thorkild I A; Gerds, Thomas A;

    2015-01-01

    OBJECTIVES: Maternal body mass index (BMI), birth weight, and preschool BMI may help identify children at high risk of overweight as they are (1) similarly linked to adolescent overweight at different stages of the obesity epidemic, (2) linked to adult obesity and metabolic alterations, and (3......) easily obtainable in health examinations in young children. The aim was to develop early childhood prediction models of adolescent overweight, adult overweight, and adult obesity. METHODS: Prediction models at various ages in the Northern Finland Birth Cohort born in 1966 (NFBC1966) were developed...... a subgroup of children at very high risk of becoming overweight, which may be valuable in public health settings dealing with obesity prevention....

  1. Parent Discrimination Predicts Mexican-American Adolescent Psychological Adjustment 1 Year Later.

    Science.gov (United States)

    Espinoza, Guadalupe; Gonzales, Nancy A; Fuligni, Andrew J

    2016-07-01

    This study examined whether Mexican-American parents' experiences with discrimination are related to adolescent psychological adjustment over time. The extent to which associations between parent discrimination and adolescent adjustment vary as a function of parents' ethnic socialization of their children was also examined. Participants included 344 high school students from Mexican or Mexican-American backgrounds (primarily second generation; ages 14-16 at Wave 1) and their primary caregivers who completed surveys in a 2-year longitudinal study. Results revealed that parent discrimination predicted internalizing symptoms and self-esteem among adolescents 1 year later. Additionally, adolescents were more likely to report low self-esteem in relation to parents' increased experiences of discrimination when parents conveyed ethnic socialization messages to them. PMID:27224903

  2. Popularity differentially predicts reactive and proactive aggression in early adolescence.

    Science.gov (United States)

    Stoltz, Sabine; Cillessen, Antonius H N; van den Berg, Yvonne H M; Gommans, Rob

    2016-01-01

    Previous research has indicated that peer popularity is associated with aggressive behavior. However, it is not yet clear whether popularity is uniquely related to different functions of aggression. In this study, we examined associations between peer-perceived popularity, and reactive and proactive aggression using a cross-sectional and a longitudinal design. Yearly sociometric measures of popularity, and reactive and proactive aggression were gathered from 266 seventh and eight grade adolescents (Mage grade 7 = 12.80, SDage  = .40). Popularity was positively correlated with proactive aggression and negatively correlated with reactive aggression, both concurrently as over time. Curvilinear trends indicated that a significant minority of low versus high popular adolescents showed both functions of aggression. Somewhat stronger effects of popularity on proactive aggression were found for boys than girls. Stably popular adolescents showed the highest levels of proactive aggression, whereas stably unpopular youth showed the highest levels of reactive aggression. Implications and directions for future research are discussed.

  3. Ethnic identity trajectories among Mexican-origin girls during early and middle adolescence: Predicting future psychosocial adjustment.

    Science.gov (United States)

    Gonzales-Backen, Melinda A; Bámaca-Colbert, Mayra Y; Allen, Kimberly

    2016-05-01

    We examined trajectories of ethnic identity exploration, resolution, and affirmation and their associations with depressive symptoms and self-esteem 3.5 years later among early and middle adolescent Mexican-origin girls (N = 338). Findings indicated that exploration, resolution, and affirmation increased over time for both cohorts. Among early adolescents, growth in exploration was associated with more depressive symptoms during middle adolescence, whereas higher initial levels and greater rates of change of affirmation predicted fewer subsequent depressive symptoms. Among middle adolescents, higher baseline levels of exploration and affirmation predicted fewer depressive symptoms in late adolescence. Higher initial levels and greater change in affirmation predicted higher self-esteem among both cohorts. Findings highlight the developmental and multifaceted quality of ethnic identity and that associations between ethnic identity and adjustment may vary by adolescent developmental stage. (PsycINFO Database Record PMID:26986228

  4. Perceptions of the School Psychological Environment in Predicting Adolescent Mothers' Educational Expectations.

    Science.gov (United States)

    Kalil, Ariel

    2002-01-01

    Drawing on theories of educational motivation, this study investigated how perceptions of the school psychological environment predict change over time in educational expectations among low-income adolescent mothers. Findings indicated that teenage mothers' perceptions that teachers devalued them intellectually by underestimating their abilities…

  5. Using Marital Attitudes in Late Adolescence to Predict Later Union Transitions

    Science.gov (United States)

    Willoughby, Brian J.

    2014-01-01

    Using a sample of 982 late adolescents and tracking them throughout young adulthood, this study investigated whether marital attitudes held during the last year of high school were predictive of union transitions to both cohabitation and marriage during young adulthood. Results using both logistic regression and discrete event history models found…

  6. Implicit Theories of Intelligence Predict Achievement across an Adolescent Transition: A Longitudinal Study and an Intervention

    Science.gov (United States)

    Blackwell, Lisa S.; Trzesniewski, Kali H.; Dweck, Carol Sorich

    2007-01-01

    Two studies explored the role of implicit theories of intelligence in adolescents' mathematics achievement. In Study 1 with 373 7th graders, the belief that intelligence is malleable (incremental theory) predicted an upward trajectory in grades over the two years of junior high school, while a belief that intelligence is fixed (entity theory)…

  7. Predicting Sexual Re-Offending in a UK Sample of Adolescents with Intellectual Disabilities

    Science.gov (United States)

    Griffin, Helen Louise; Vettor, Shannon

    2012-01-01

    The current study aimed to address the paucity of research and assessment tools for adolescent males with intellectual disabilities who have sexually harmed, by comparing the predictive accuracy of the AIM2 assessment, developed with populations without intellectual disabilities, and the adapted AIM assessment, designed for this group. The sample…

  8. Does Self-Determination Predict the School Engagement of Four Different Motivation Types in Adolescence?

    Science.gov (United States)

    Raufelder, Diana; Regner, Nicola; Drury, Kate; Eid, Michael

    2016-01-01

    In order to enhance our understanding of inter-individual differences in scholastic motivation, this study examined if self-determination predicts the school engagement of four different motivation types (MT) in a large sample of adolescent students (N = 1088) from Brandenburg, Germany: (1) peer-dependent MT, (2) teacher-dependent MT, (3)…

  9. Dominant Goal Orientations Predict Differences in Academic Achievement during Adolescence through Metacognitive Self-Regulation

    NARCIS (Netherlands)

    Dekker, Sanne; Krabbendam, Lydia; Lee, Nikki; Boschloo, Annemarie; De Groot, Renate; Jolles, Jelle

    2016-01-01

    This study investigated whether academic achievement was predicted by the goal which generally drives a student’s learning behaviour. Secondly, the role of metacognitive self-regulation was examined. The dominant goal orientation was assessed using a new method. 735 adolescents aged 10-19 years read

  10. Using Theory of Planned Behavior to Predict Healthy Eating among Danish Adolescents

    Science.gov (United States)

    Gronhoj, Alice; Bech-Larsen, Tino; Chan, Kara; Tsang, Lennon

    2013-01-01

    Purpose: The purpose of the study was to apply the theory of planned behavior to predict Danish adolescents' behavioral intention for healthy eating. Design/methodology/approach: A cluster sample survey of 410 students aged 11 to 16 years studying in Grade 6 to Grade 10 was conducted in Denmark. Findings: Perceived behavioral control followed by…

  11. A nomogram to predict the probability of passing the American Board of Internal Medicine examination

    Directory of Open Access Journals (Sweden)

    Andrei Brateanu

    2012-10-01

    Full Text Available Background : Although the American Board of Internal Medicine (ABIM certification is valued as a reflection of physicians’ experience, education, and expertise, limited methods exist to predict performance in the examination. Purpose : The objective of this study was to develop and validate a predictive tool based on variables common to all residency programs, regarding the probability of an internal medicine graduate passing the ABIM certification examination. Methods : The development cohort was obtained from the files of the Cleveland Clinic internal medicine residents who began training between 2004 and 2008. A multivariable logistic regression model was built to predict the ABIM passing rate. The model was represented as a nomogram, which was internally validated with bootstrap resamples. The external validation was done retrospectively on a cohort of residents who graduated from two other independent internal medicine residency programs between 2007 and 2011. Results : Of the 194 Cleveland Clinic graduates used for the nomogram development, 175 (90.2% successfully passed the ABIM certification examination. The final nomogram included four predictors: In-Training Examination (ITE scores in postgraduate year (PGY 1, 2, and 3, and the number of months of overnight calls in the last 6 months of residency. The nomogram achieved a concordance index (CI of 0.98 after correcting for over-fitting bias and allowed for the determination of an estimated probability of passing the ABIM exam. Of the 126 graduates from two other residency programs used for external validation, 116 (92.1% passed the ABIM examination. The nomogram CI in the external validation cohort was 0.94, suggesting outstanding discrimination. Conclusions : A simple user-friendly predictive tool, based on readily available data, was developed to predict the probability of passing the ABIM exam for internal medicine residents. This may guide program directors’ decision

  12. The Cognitive Processes underlying Affective Decision-making Predicting Adolescent Smoking Behaviors in a Longitudinal Study

    Directory of Open Access Journals (Sweden)

    Lin eXiao

    2013-10-01

    Full Text Available This study investigates the relationship between three different cognitive processes underlying the Iowa Gambling Task (IGT and adolescent smoking behaviors in a longitudinal study. We conducted a longitudinal study of 181 Chinese adolescents in Chengdu City, China. The participants were followed from 10th grade to 11th grade. When they were in the 10th grade (Time 1, we tested these adolescents’ decision-making using the Iowa Gambling Task and working memory capacity using the Self-ordered Pointing Test (SOPT. Self-report questionnaires were used to assess school academic performance and smoking behaviors. The same questionnaires were completed again at the one-year follow-up (Time 2. The Expectancy-Valence (EV Model was applied to distill the IGT performance into three different underlying psychological components: (i a motivational component which indicates the subjective weight the adolescents assign to gains versus losses; (ii a learning-rate component which indicates the sensitivity to recent outcomes versus past experiences; and (iii a response component which indicates how consistent the adolescents are between learning and responding. The subjective weight to gains vs. losses at Time 1 significantly predicted current smokers and current smoking levels at Time 2, controlling for demographic variables and baseline smoking behaviors. Therefore, by decomposing the IGT into three different psychological components, we found that the motivational process of weight gain vs. losses may serve as a neuropsychological marker to predict adolescent smoking behaviors in a general youth population.

  13. BMI predicts emotion-driven impulsivity and cognitive inflexibility in adolescents with excess weight.

    Science.gov (United States)

    Delgado-Rico, Elena; Río-Valle, Jacqueline S; González-Jiménez, Emilio; Campoy, Cristina; Verdejo-García, Antonio

    2012-08-01

    Adolescent obesity is increasingly viewed as a brain-related dysfunction, whereby reward-driven urges for pleasurable foods "hijack" response selection systems, such that behavioral control progressively shifts from impulsivity to compulsivity. In this study, we aimed to examine the link between personality factors (sensitivity to reward (SR) and punishment (SP), BMI, and outcome measures of impulsivity vs. flexibility in--otherwise healthy--excessive weight adolescents. Sixty-three adolescents (aged 12-17) classified as obese (n = 26), overweight (n = 16), or normal weight (n = 21) participated in the study. We used psychometric assessments of the SR and SP motivational systems, impulsivity (using the UPPS-P scale), and neurocognitive measures with discriminant validity to dissociate inhibition vs. flexibility deficits (using the process-approach version of the Stroop test). We tested the relative contribution of age, SR/SP, and BMI on estimates of impulsivity and inhibition vs. switching performance using multistep hierarchical regression models. BMI significantly predicted elevations in emotion-driven impulsivity (positive and negative urgency) and inferior flexibility performance in adolescents with excess weight--exceeding the predictive capacity of SR and SP. SR was the main predictor of elevations in sensation seeking and lack of premeditation. These findings demonstrate that increases in BMI are specifically associated with elevations in emotion-driven impulsivity and cognitive inflexibility, supporting a dimensional path in which adolescents with excess weight increase their proneness to overindulge when under strong affective states, and their difficulties to switch or reverse habitual behavioral patterns. PMID:22421897

  14. Using Marital Attitudes in Late Adolescence to Predict Later Union Transitions

    OpenAIRE

    Willoughby, Brian J.

    2012-01-01

    Using a sample of 982 late adolescents and tracking them throughout young adulthood, this study investigated if marital attitudes held during the last year of high school were predictive of union transitions to both cohabitation and marriage during young adulthood. Results using both logistic regression and discrete event history models found that marital attitudes did not have significant associations with the transition to cohabitation but did significantly predict the probability of transi...

  15. Does psychopathology in childhood predict internet addiction in male adolescents?

    Science.gov (United States)

    Cho, Sun-Mi; Sung, Min-Je; Shin, Kyoung-Min; Lim, Ki Young; Shin, Yun-Mi

    2013-08-01

    This study investigated childhood psychopathology and Internet addiction in adolescents. Initial assessment data were obtained from 1998 to 1999, and a follow-up assessment was performed in 2006, when the original subjects entered middle school. Personal information for the 524 male subjects was obtained from the original data. The subjects were evaluated with the Korean version of the child behavior checklist, which was administered to the children's parents. Demographic and psychosocial factors were also evaluated. Children were reassessed with the self-reported Korea Internet Addiction Scale. Our results indicated that 3.6 % of the subjects had Internet addiction, and revealed a significant relationship between withdrawal and anxiety/depression and future Internet addiction. The results suggest that withdrawal and anxiety/depression during childhood should be considered in the etiology of problematic Internet use in boys. Accordingly, clinicians should consider anxiety/depression and withdrawal during childhood to prevent Internet addiction.

  16. Stability of executive function and predictions to adaptive behavior from middle childhood to pre-adolescence

    Directory of Open Access Journals (Sweden)

    Madeline eHarms

    2014-04-01

    Full Text Available The shift from childhood to adolescence is characterized by rapid remodeling of the brain and increased risk-taking behaviors. Current theories hypothesize that developmental enhancements in sensitivity to affective environmental cues in adolescence may undermine executive function (EF and increase the likelihood of problematic behaviors. In the current study, we examined the extent to which EF in childhood predicts EF in early adolescence. We also tested whether individual differences in neural responses to affective cues (rewards/punishments in childhood serve as a biological marker for EF, sensation-seeking, academic performance, and social skills in early adolescence. At age 8, 84 children completed a gambling task while event-related potentials (ERPs were recorded. We examined the extent to which selections resulting in rewards or losses in this task elicited (i the P300, a post-stimulus waveform reflecting the allocation of attentional resources toward a stimulus, and (ii the SPN, a pre-stimulus anticipatory waveform reflecting a neural representation of a hunch about an outcome that originates in insula and ventromedial PFC. Children also completed a Dimensional Change Card-Sort (DCCS and Flanker task to measure EF. At age 12, 78 children repeated the DCCS and Flanker and completed a battery of questionnaires. Flanker and DCCS accuracy at age 8 predicted Flanker and DCCS performance at age 12, respectively. Individual differences in the magnitude of P300 (to losses vs. rewards and SPN (preceding outcomes with a high probability of punishment at age 8 predicted self-reported sensation seeking (lower and teacher-rated academic performance (higher at age 12. We suggest there is stability in EF from age 8 to 12, and that childhood neural sensitivity to reward and punishment predicts individual differences in sensation seeking and adaptive behaviors in children entering adolescence.

  17. Childhood Internalizing and Externalizing Problems Predict the Onset of Clinical Panic Attacks over Adolescence: The TRAILS Study

    OpenAIRE

    Mathyssek, Christina M.; Olino, Thomas M.; Verhulst, Frank C.; Oort, Floor V. A.

    2012-01-01

    textabstractBackground: Panic attacks are a source of individual suffering and are an independent risk factor for later psychopathology. However, much less is known about risk factors for the development of panic attacks, particularly during adolescence when the incidence of panic attacks increases dramatically. We examined whether internalizing and externalizing problems in childhood predict the onset of panic attacks in adolescence. Method: This study is part of the TRacking Adolescents' In...

  18. The Broader Context of Relational Aggression in Adolescent Romantic Relationships: Predictions from Peer Pressure and Links to Psychosocial Functioning

    OpenAIRE

    Schad, Megan M.; Szwedo, David E.; Antonishak, Jill; Hare, Amanda; Allen, Joseph P.

    2008-01-01

    The broader context of relational aggression in adolescent romantic relationships was assessed by considering the ways such aggression emerged from prior experiences of peer pressure and was linked to concurrent difficulties in psychosocial functioning. Longitudinal, multi-reporter data were obtained from 97 adolescents and their best friends at age 15 and from adolescents and their romantic partners at age 18. Teens’ relational aggression and romantic partners’ victimization were predicted f...

  19. The interaction between self-regulation and motivation prospectively predicting problem behavior in adolescence.

    Science.gov (United States)

    Rhodes, Jessica D; Colder, Craig R; Trucco, Elisa M; Speidel, Carolyn; Hawk, Larry W; Lengua, Liliana J; Das Eiden, Rina; Wieczorek, William

    2013-01-01

    A large literature suggests associations between self-regulation and motivation and adolescent problem behavior; however, this research has mostly pitted these constructs against one another or tested them in isolation. Following recent neural-systems based theories (e.g., Ernst & Fudge, 2009 ), the present study investigated the interactions between self-regulation and approach and avoidance motivation prospectively predicting delinquency and depressive symptoms in early adolescence. The community sample included 387 adolescents aged 11 to 13 years old (55% female; 17% minority). Laboratory tasks were used to assess self-regulation and approach and avoidance motivation, and adolescent self-reports were used to measure depressive symptoms and delinquency. Analyses suggested that low levels of approach motivation were associated with high levels of depressive symptoms, but only at high levels of self-regulation (p = .01). High levels of approach were associated with high levels of rule breaking, but only at low levels of self-regulation (p < .05). These findings support contemporary neural-based systems theories that posit integration of motivational and self-regulatory individual differences via moderational models to understand adolescent problem behavior. PMID:23477426

  20. Are Executive Functioning Deficits Concurrently and Predictively Associated with Depressive and Anxiety Symptoms in Adolescents?

    Science.gov (United States)

    Han, Georges; Helm, Jonathan; Iucha, Cornelia; Zahn-Waxler, Carolyn; Hastings, Paul D; Klimes-Dougan, Bonnie

    2016-01-01

    The central objective of the current study was to evaluate how executive functions (EF), and specifically cognitive flexibility, were concurrently and predictively associated with anxiety and depressive symptoms in adolescence. Adolescents (N = 220) and their parents participated in this longitudinal investigation. Adolescents' EF was assessed by the Wisconsin Card Sorting Test (WCST) during the initial assessment, and symptoms of depressive and anxiety disorders were reported by mothers and youths concurrently and 2 years later. Correlational analyses suggested that youths who made more total errors (TE), including both perseverative errors (PE) and nonperseverative errors (NPE), concurrently exhibited significantly more depressive symptoms. Adolescents who made more TE and those who made more NPE tended to have more anxiety symptoms 2 years later. Structural equation modeling analyses accounting for key explanatory variables (e.g., IQ, disruptive behavior disorders, and attention deficit hyperactive disorder) showed that TE was concurrently associated with parent reports of adolescent depressive symptoms. The results suggest internalizing psychopathology is associated with global (TE) and nonspecific (NPE) EF difficulties but not robustly associated with cognitive inflexibility (PE). Future research with the WCST should consider different sources of errors that are posited to reflect divergent underlying neural mechanisms, conferring differential vulnerability for emerging mental health problems. PMID:26042358

  1. Positive parenting predicts the development of adolescent brain structure: A longitudinal study

    Directory of Open Access Journals (Sweden)

    Sarah Whittle

    2014-04-01

    Full Text Available Little work has been conducted that examines the effects of positive environmental experiences on brain development to date. The aim of this study was to prospectively investigate the effects of positive (warm and supportive maternal behavior on structural brain development during adolescence, using longitudinal structural MRI. Participants were 188 (92 female adolescents, who were part of a longitudinal adolescent development study that involved mother–adolescent interactions and MRI scans at approximately 12 years old, and follow-up MRI scans approximately 4 years later. FreeSurfer software was used to estimate the volume of limbic-striatal regions (amygdala, hippocampus, caudate, putamen, pallidum, and nucleus accumbens and the thickness of prefrontal regions (anterior cingulate and orbitofrontal cortices across both time points. Higher frequency of positive maternal behavior during the interactions predicted attenuated volumetric growth in the right amygdala, and accelerated cortical thinning in the right anterior cingulate (males only and left and right orbitofrontal cortices, between baseline and follow up. These results have implications for understanding the biological mediators of risk and protective factors for mental disorders that have onset during adolescence.

  2. Predictive factors for latent tuberculosis infection among adolescents in a high-burden area in South Africa

    NARCIS (Netherlands)

    H. Mahomed; T. Hawkridge; S. Verver; L. Geiter; M. Hatherill; D.A. Abrahams; R. Ehrlich; W.A. Hanekom; G.D. Hussey

    2011-01-01

    SETTING: A high tuberculosis (TB) burden area in South Africa (notification rate for all TB cases 1400 per 100 000 population). OBJECTIVE: To determine the prevalence of and predictive factors associated with latent TB infection in adolescents. DESIGN: Adolescents aged 12-18 years were recruited fro

  3. Predicting Desire for a Child among Low-Income Urban Adolescent Girls: Interpersonal Processes in the Context of Poverty.

    Science.gov (United States)

    Grant, Kathryn; Grace, Pamela; Trujillo, Jaime; Halpert, Jane; Kessler-Cordeiro, Anna; Razzino, Brian; Davis, Trina

    2002-01-01

    Interpersonal influences on the desire to have a child were examined in a sample of pregnant low-income urban adolescents. It was hypothesized that adolescent girls who report poorer relationships with their parents would report greater emotional reliance on their boyfriends and greater reliance on boyfriends would predict greater desire for a…

  4. Predictive Medicine: Recombinant DNA Technology and Adult-Onset Genetic Disorders

    OpenAIRE

    Hayden, Michael

    1988-01-01

    Genetic factors are of great importance in common adult-onset disorders such as atherosclerosis, cancer, and neuro-degenerative diseases. Advances in DNA technology now allow identification of persons at high-risk of developing some of these diseases. This advance is leading to predictive medicine. In some genetic disorders, such as those leading to atherosclerosis and cancer, identification of high-risk individuals allows intervention which alters the natural history of the disorder. In othe...

  5. Executive Dysfunction Predicts Delinquency But Not Characteristics of Sexual Aggression Among Adolescent Sexual Offenders.

    Science.gov (United States)

    Burton, David; Demuynck, Sophia; Yoder, Jamie R

    2014-11-25

    Our aim in this study was to evaluate executive function and its relationship to delinquency and sexual crime in adolescents incarcerated for sexual crimes. Based on self-report data, 196 male adolescent sexual offenders from a Midwest state reported high rates of executive dysfunction. Although such deficits did not relate to the number of victims of sexual abuse, severity, or degree of force used in commission of the sexual crimes, poor executive function was significantly predictive of both general delinquency and felony theft. In both measures of delinquent conduct, behavioral regulation dysfunction was predictive of the frequency of commission of the crimes, whereas metacognition was not. Research and treatment implications are offered. PMID:25428928

  6. Prediction Model for Predicting Powdery Mildew using ANN for Medicinal Plant—Picrorhiza kurrooa

    Science.gov (United States)

    Shivling, V. D.; Ghanshyam, C.; Kumar, Rakesh; Kumar, Sanjay; Sharma, Radhika; Kumar, Dinesh; Sharma, Atul; Sharma, Sudhir Kumar

    2016-06-01

    Plant disease fore casting system is an important system as it can be used for prediction of disease, further it can be used as an alert system to warn the farmers in advance so as to protect their crop from being getting infected. Fore casting system will predict the risk of infection for crop by using the environmental factors that favor in germination of disease. In this study an artificial neural network based system for predicting the risk of powdery mildew in Picrorhiza kurrooa was developed. For development, Levenberg-Marquardt backpropagation algorithm was used having a single hidden layer of ten nodes. Temperature and duration of wetness are the major environmental factors that favor infection. Experimental data was used as a training set and some percentage of data was used for testing and validation. The performance of the system was measured in the form of the coefficient of correlation (R), coefficient of determination (R2), mean square error and root mean square error. For simulating the network an inter face was developed. Using this interface the network was simulated by putting temperature and wetness duration so as to predict the level of risk at that particular value of the input data.

  7. Predicting the Sprint Performance of Adolescent Track Cyclists Using the 3-Minute All-out Test.

    Science.gov (United States)

    Waldron, Mark; Gray, Adrian; Furlan, Nicola; Murphy, Aron

    2016-08-01

    Waldron, M, Gray, A, Furlan, N, and Murphy, A. Predicting the sprint performance of adolescent track cyclists using the 3-minute all-out test. J Strength Cond Res 30(8): 2299-2306, 2016-This study aimed to predict 500-m time trial (TT) and 2,000-m pursuit speed of adolescent cyclists (age range = 13-15 years) using mechanical parameters derived from a critical power (CP) test and anthropometric variables. Ten well-trained competitive cyclists were assessed for body composition, body mass, stature, and frontal surface area (FSA), as well as completing the CP test. The personal best speed (km·h) of each rider during competition in 500-m TT and 2,000-m pursuit races was predicted based on the CP test data and anthropometric profiles using multiple regression analysis. A combination of the CP·FSA and internal (predicted) to external work ratio performed by the cyclists (Wint:Wext) predicted 500-m TT speed (R = 0.97; standard error of the estimate (SEE) = 0.82, P ≤ 0.001), whereas a combination of mean power·FSA (mean power) and body fat percentage predicted 2,000-m pursuit speed (R = 0.90; SEE = 1.5, p < 0.001). Between 90 and 97% of the variance in the sprint performance of adolescent cyclists can be explained by mechanical and anthropometric parameters, derived from a single visit to the laboratory. The tests and equations provided can be adopted by coaches to predict performance and set appropriate training intensities. PMID:26694504

  8. The Role of Parenting Styles in Predicting Anxiety Thoughts and Obsessive Compulsive Symptoms in Adolescents

    OpenAIRE

    Z Khanjani; B Esmaeili Anamage; M Gholamzadeh

    2012-01-01

    Introduction: Parents interaction styles with children or teens have an important impact on shaping their character and mental health and the incidence of some psychiatric symptoms. The aim of this study was to predict anxiety thought and obsessive - compulsive symptoms of the adolescents based on parents' parenting styles. Methods: This was a descriptive study. 180 male students in Marand were selected by cluster random sampling. We used Baumrind parents parenting style questionnaire, Wales ...

  9. Neurocognitive processes and the prediction of addictive behaviors in late adolescence

    OpenAIRE

    Wiers, R. W.; Gladwin, T.E.; Korucuoğlu, Ö.

    2015-01-01

    The primary aim of this dissertation was to investigate the effect of acute alcohol on neurocognitive systems involved in the development of addictive behaviours in adolescents. A secondary aim was to investigate whether alcohol-induced changes in cognitive and affective processes would be predictive of alcohol escalation in young people. Tasks that tap into cognitive control, implicit and explicit action tendencies were used to assess late adolescents’ brain responses after alcohol administr...

  10. Parent-child math anxiety and math-gender stereotypes predict adolescents' math education outcomes

    OpenAIRE

    Casad, Bettina J.; Hale, Patricia; Wachs, Faye L.

    2015-01-01

    Two studies examined social determinants of adolescents' math anxiety including parents' own math anxiety and children's endorsement of math-gender stereotypes. In Study 1, parent-child dyads were surveyed and the interaction between parent and child math anxiety was examined, with an eye to same- and other-gender dyads. Results indicate that parent's math anxiety interacts with daughters' and sons' anxiety to predict math self-efficacy, GPA, behavioral intentions, math attitudes, and math de...

  11. Predictive value and rate of change of blood pressure throughout adolescence : a Belgian prospective study

    OpenAIRE

    Saint-Remy, Annie; Rorive, Georges

    1991-01-01

    We performed a prospective study on the natural course of blood pressure throughout adolescence. The major goals were to assess the predictive value of a high blood pressure level at the age of 12 years and the feasibilty of developing a screening test for the early detection of young subjects at risk of developing chronic hypertension. By measuring the relationship between the initial level and subsequent changes in blood pressure, we looked for a phenomenon previously demonstrated in adults...

  12. Duration of Early Maternal Separation and Prediction of Schizotypal Symptoms from Early Adolescence to Midlife

    OpenAIRE

    Anglin, Deidre M.; Cohen, Patricia R.; Chen, Henian

    2008-01-01

    Early childhood experiences influence the capacity for healthy social and emotional development. The present study uses longitudinal data to determine whether early maternal separation predicted the subsequent development of schizotypal personality disorder (SPD) symptoms assessed repeatedly from early adolescence over the following 20 years. Within this community sample (N=766), multilevel linear regression analyses revealed the duration of separation from mother in the first 2 years of life...

  13. Can scapular and humeral head position predict shoulder pain in adolescent swimmers and non-swimmers?

    Science.gov (United States)

    McKenna, Leanda; Straker, Leon; Smith, Anne

    2012-12-01

    The aims of this study were to determine whether scapular and humeral head position can predict the development of shoulder pain in swimmers, whether those predictors were applicable to non-swimmers and the annual rate of shoulder pain in adolescent swimmers and non-swimmers. Forty-six adolescent swimmers and 43 adolescent non-swimmers were examined prospectively with a questionnaire and anthropometric measures. The questionnaire examined demographic and training variables. Anthropometric measures examined the distances between the T7 spinous process and the inferior scapula (Inferior Kibler) and T3 spinous process and the medial spine of the scapula (Superior Kibler), humeral head position in relation to the acromion using palpation, BMI and chest width. Shoulder pain was re-assessed 12 months later by questionnaire. Shoulder pain in swimmers was best predicted by a larger BMI (OR = 1.48, P = 0.049), a smaller Inferior Kibler distance in abduction (e.g. OR = 0.90, P = 0.009) and a smaller horizontal distance between the anterior humeral head and the anterior acromion (OR = 0.76, P = 0.035). These variables were not significantly predictive of shoulder pain in non-swimmers. Annual prevalence of shoulder pain was 23.9% in swimmers and 30.8% in non-swimmers (χ(2) = 0.50, P = 0.478).

  14. Writing abilities longitudinally predict academic outcomes of adolescents with ADHD.

    Science.gov (United States)

    Molitor, Stephen J; Langberg, Joshua M; Bourchtein, Elizaveta; Eddy, Laura D; Dvorsky, Melissa R; Evans, Steven W

    2016-09-01

    Students with attention-deficit/hyperactivity disorder (ADHD) often experience a host of negative academic outcomes, and deficits in reading and mathematics abilities contribute to these academic impairments. Students with ADHD may also have difficulties with written expression, but there has been minimal research in this area and it is not clear whether written expression abilities uniquely contribute to the academic functioning of students with ADHD. The current study included a sample of 104 middle school students diagnosed with ADHD (Grades 6-8). Participants were followed longitudinally to evaluate whether written expression abilities at baseline predicted student grade point average (GPA) and parent ratings of academic impairment 18 months later, after controlling for reading ability and additional relevant covariates. Written expression abilities longitudinally predicted both academic outcomes above and beyond ADHD and oppositional defiant disorder symptoms, medication use, reading ability, and baseline values of GPA and parent-rated academic impairment. Follow-up analyses revealed that no single aspect of written expression was demonstrably more impactful on academic outcomes than the others, suggesting that writing as an entire process should be the focus of intervention. (PsycINFO Database Record

  15. Dispositional mindfulness is predicted by structural development of the insula during late adolescence

    Directory of Open Access Journals (Sweden)

    S. Friedel

    2015-08-01

    Full Text Available Adolescence is a critical period of development, in which the increasing social and cognitive demands of independence need to be met by enhanced self-regulatory abilities. The cultivation of mindfulness has been associated with improved self-regulation in adult populations, and it is theorized that one neurodevelopmental mechanism that supports this capacity is the development of the prefrontal cortex. The current study examined the neurodevelopmental mechanisms associated with dispositional mindfulness in adolescence. Using a longitudinal within-persons design, 82 participants underwent structural magnetic resonance imaging (MRI assessments at approximately ages 16 and 19, and also completed self-reported measurements of mindfulness at age 19. It was hypothesized that adolescents who demonstrated greater thinning of frontal cortical regions between the age of 16 and 19 would exhibit higher dispositional mindfulness levels at age 19. Results indicated that, contrary to predictions, adolescents with higher levels of mindfulness demonstrated less thinning in the left anterior insula. By contrast, higher IQ was associated with greater thinning of the right caudal middle frontal and right superior frontal regions. The involvement of insula development in mindfulness is consistent with a direct role for this structure in managing self-regulation, and in doing so concords with recent models of self-referential interoceptive awareness.

  16. Cut-Off Values of Visceral Adiposity to Predict NAFLD in Brazilian Obese Adolescents

    Directory of Open Access Journals (Sweden)

    Ana Paula Grotti Clemente

    2013-01-01

    Full Text Available Objectives. The present study aimed at determining cut-off points of visceral fat to predict NAFLD and analyzed metabolic disorders of obese adolescents. Methods. Cross-sectional study involved 165 obese adolescents ranged in age from 15 to 19 years. Glycemia, hepatic transaminases, lipid profile, and insulin resistance were analyzed. Visceral and subcutaneous fat were measured by ultrasound and body composition by plesthysmography. Results. The NAFLD adolescents had significantly higher values for body mass, BMI-for-age, BMI, total fat, waist circumference, and visceral fat when compared with non-NAFLD obese adolescents in both genders. Moreover, there were significant positive correlations between visceral fat with the variables BMI-for-age (r=0.325,, TG (r=0.277, AST (r=0.509, ALT (r=0.519, WC (r=0.390, and visceral/subcutaneous ratio (r=0.790 for NAFLD group. Total fat, triglycerides, and visceral fat were the independent predictors to NAFLD. Analysis of the ROC curves revealed cut-off points of visceral fat of 4.47 cm for girls and 4.21 cm for boys. Conclusions. The results may suggest that abdominal ultrasonography procedure may be a safe alternative method of assessing visceral adiposity aiming to be considered to the development of preventive and treatment strategies in obese individuals. This clinial trial is registered with ClinicalTrial.gov (NCT01358773.

  17. Predicting Aggression among Male Adolescents: an Application of the Theory of Planned Behavior

    Directory of Open Access Journals (Sweden)

    Mari Ataee

    2013-12-01

    Full Text Available Background: Aggressive behavior in adolescence can be expressed as a predictor for crime, substance abuse, depression and academic failure. The purpose of this study was to determine the prediction of aggression among Iranian adolescent based on theory of planned behavior (TPB as a theoretical framework. Methods: In this cross-sectional study, conducted in Yasuj County, south of Iran, during 2011, a total of 256 male adolescents, were randomly enrolled. Participants filled out a self-administered questionnaire. Data were analyzed by SPSS version 21 using bivariate correlations, and linear regression statistical tests at 95% significant level. Result: The three predictor variables of 1 attitude, 2 subjective norms, and 3 perceived behavioral control, accounted for 40% of the variation in the outcome measure of the aggression intention. Besides, intention accounted for 15% of the variation in the outcome measure of the aggression behavior. There was a significant correlation between drug abuse and alcohol consumption, have friend drug user, unprotect sex and parents divorced with aggression (P< 0.05. Conclusions: Designing intervention to reduction positive attitude and subjective norms toward aggressive behavior among adolescents could be use-fulness result to aggression prevention.

  18. Predicting Depressive Symptoms and Weight from Adolescence to Adulthood: Stressors and the Role of Protective Factors.

    Science.gov (United States)

    Carter, Jocelyn Smith; Dellucci, Trey; Turek, Carolyn; Mir, Sophie

    2015-11-01

    Depressive symptoms and weight gain follow similar developmental trajectories from adolescence to adulthood and stressors are a risk factor for both. However, less is known about whether they share protective factors that reduce the risk for depressive symptoms and weight gain. The goal of the current study was to examine the role of stress and four protective factors (social support, self-esteem, physical activity, and sedentary behavior) as predictors of depressive symptoms and body mass index over time. Participating in the current study were 6504 (51.6 % female; 60.7 % European American, 22.5 % African American, 11.4 % Hispanic, 3.3 % Asian American, and 2 % other ethnicities) adolescents from the National Study of Adolescent and Adult Health. Participants were followed for three waves from adolescence to young adulthood (Wave I age range = 12-18; Wave III age range = 18-26). Data were analyzed using multi-level modeling and results showed that stressors significantly predicted trajectories of depressive symptoms and body mass index over time. Social support buffered the effects of stressors on BMI over time. Self-esteem influenced trajectories of both BMI and depressive symptoms. Differential effects were found for physical activity with physical activity predicting declines in depressive symptoms and sedentary behavior predicting declines in BMI over time. The current study suggests that stress is a common risk factor for depressive symptoms and weight gain, but that there is specificity in how the protective factors influence each type of outcome. PMID:25990673

  19. The application of observational data in translational medicine: analyzing tobacco-use behaviors of adolescents

    Directory of Open Access Journals (Sweden)

    Siciliano Valeria

    2012-05-01

    Full Text Available Abstract Background Translational Medicine focuses on “bench to bedside”, converting experimental results into clinical use. The “bedside to bench” transition remains challenging, requiring clinicians to define true clinical need for laboratory study. In this study, we show how observational data (an eleven-year data survey program on adolescent smoking behaviours, can identify knowledge gaps and research questions leading directly to clinical implementation and improved health care. We studied gender-specific trends (2000–2010 in Italian students to evaluate the specific impact of various anti-smoking programs, including evaluation of perceptions of access to cigarettes and health risk. Methods The study used, ESPAD-Italia® (European School Survey Project on Alcohol and other Drugs, is a nationally representative sample of high-school students. The permutation test for joinpoint regression was used to calculate the annual percent change in smoking. Changes in smoking habits by age, perceived availability and risk over a 11-year period were tested using a gender-specific logistic model and a multinomial model. Results Gender-stratified analysis showed 1 decrease of lifetime prevalence, then stabilization (both genders; 2 decrease in last month and occasional use (both genders; 3 reduction of moderate use (females; 4 no significant change in moderate use (males and in heavy use (both genders. Perceived availability positively associates with prevalence, while perceived risk negatively associates, but interact with different effects depending on smoking patterns. In addition, government implementation of public policies concerning access to tobacco products in this age group during this period presented a unique background to examine their specific impact on behaviours. Conclusion Large observational databases are a rich resource in support of translational research. From these observations, key clinically relevant issues can be

  20. Bullying Predicts Reported Dating Violence and Observed Qualities in Adolescent Dating Relationships.

    Science.gov (United States)

    Ellis, Wendy E; Wolfe, David A

    2015-10-01

    The relationship between reported bullying, reported dating violence, and dating relationship quality measured through couple observations was examined. Given past research demonstrating similarity between peer and dating contexts, we expected that bullying would predict negative dating experiences. Participants with dating experience (n = 585; 238 males, M(age) = 15.06) completed self-report assessments of bullying and dating violence perpetration and victimization. One month later, 44 opposite-sex dyads (M(age) = 15.19) participated in behavioral observations. In 10-min sessions, couples were asked to rank and discuss areas of relationship conflict while being video-recorded. Qualities of the relationship were later coded by trained observers. Regression analysis revealed that bullying positively predicted dating violence perpetration and victimization. Self-reported bullying also predicted observations of lower relationship support and higher withdrawal. Age and gender interactions further qualified these findings. The bullying of boys, but not girls, was significantly related to dating violence perpetration. Age interactions showed that bullying was positively predictive of dating violence perpetration and victimization for older, but not younger adolescents. Positive affect was also negatively predicted by bullying, but only for girls. These findings add to the growing body of evidence that adolescents carry forward strategies learned in the peer context to their dating relationships. PMID:25355858

  1. New predictive equations for estimation of basal metabolic rates of adolescents: tropics versus temperate.

    Science.gov (United States)

    Noor, M I; Poh, B K; Zawiah, H; Henry, C J K

    2003-01-01

    The energy and nutritional requirements of adolescents are influenced primarily by the growth spurt that occurs at puberty, and also by the need to maintain adequate levels of physical activity. Predictions of BMR have gained attention since the publication of the FAO/WHO/UNU (1985) expert consultation report, which adopted the principle of relying on energy expenditure rather than energy intake to derive requirement of individuals. While the report predicts BMR accurately in many individuals from temperate climate, they are said to be less accurate in predicting BMR in populations living in the tropics. The collation of worldwide data on basal metabolism indicated that, relative to adults, there was a paucity of data in other age groups including the adolescents. Although several BMR studies among children had been reported in the 90's, the data in normal weight children are almost exclusively from small control groups in obesity studies. Furthermore, we know little as to whether BMR of children differs in differing climatic conditions. This paper presents predictive equations for estimating BMR from a two-centre study, Bangi (Malaysia) and Oxford (UK) and to compare the results with the currently used predictive equations. PMID:15806886

  2. Bullying Predicts Reported Dating Violence and Observed Qualities in Adolescent Dating Relationships.

    Science.gov (United States)

    Ellis, Wendy E; Wolfe, David A

    2015-10-01

    The relationship between reported bullying, reported dating violence, and dating relationship quality measured through couple observations was examined. Given past research demonstrating similarity between peer and dating contexts, we expected that bullying would predict negative dating experiences. Participants with dating experience (n = 585; 238 males, M(age) = 15.06) completed self-report assessments of bullying and dating violence perpetration and victimization. One month later, 44 opposite-sex dyads (M(age) = 15.19) participated in behavioral observations. In 10-min sessions, couples were asked to rank and discuss areas of relationship conflict while being video-recorded. Qualities of the relationship were later coded by trained observers. Regression analysis revealed that bullying positively predicted dating violence perpetration and victimization. Self-reported bullying also predicted observations of lower relationship support and higher withdrawal. Age and gender interactions further qualified these findings. The bullying of boys, but not girls, was significantly related to dating violence perpetration. Age interactions showed that bullying was positively predictive of dating violence perpetration and victimization for older, but not younger adolescents. Positive affect was also negatively predicted by bullying, but only for girls. These findings add to the growing body of evidence that adolescents carry forward strategies learned in the peer context to their dating relationships.

  3. Traditional, complementary and alternative medical systems and their contribution to personalisation, prediction and prevention in medicine-person-centred medicine.

    Science.gov (United States)

    Roberti di Sarsina, Paolo; Alivia, Mauro; Guadagni, Paola

    2012-01-01

    Traditional, complementary and alternative medical (TCAM) systems contribute to the foundation of person-centred medicine (PCM), an epistemological orientation for medical science which places the person as a physical, psychological and spiritual entity at the centre of health care and of the therapeutic process. PCM wishes to broaden the bio-molecular reductionistic approach of medical science towards an integration that allows people, doctors, nurses, health-care professionals and patients to become the real protagonists of the health-care scene. The doctor or caregiver needs to act out of empathy to meet the unique value of each human being, which unfolds over the course of a lifetime from conception to natural death. Knowledge of the human being should not be instrumental to economic or political interests, ideology, theories or religious dogma. Research needs to be broadened with methodological tools to investigate person-centred medical interventions. Salutogenesis is a fundamental principle of PCM, promoting health and preventing illness by strengthening the individual's self-healing abilities. TCAM systems also give tools to predict the insurgence of illness and treat it before the appearance of overt organic disease. A task of PCM is to educate people to take better care of their physical, psychological and spiritual health. Health-care education needs to be broadened to give doctors and health-care workers of the future the tools to act in innovative and highly differentiated ways, always guided by deep respect for individual autonomy, personal culture, religion and beliefs. PMID:23126628

  4. Clinical implications of omics and systems medicine: focus on predictive and individualized treatment.

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    Benson, M

    2016-03-01

    Many patients with common diseases do not respond to treatment. This is a key challenge to modern health care, which causes both suffering and enormous costs. One important reason for the lack of treatment response is that common diseases are associated with altered interactions between thousands of genes, in combinations that differ between subgroups of patients who do or do not respond to a given treatment. Such subgroups, or even distinct disease entities, have been described recently in asthma, diabetes, autoimmune diseases and cancer. High-throughput techniques (omics) allow identification and characterization of such subgroups or entities. This may have important clinical implications, such as identification of diagnostic markers for individualized medicine, as well as new therapeutic targets for patients who do not respond to existing drugs. For example, whole-genome sequencing may be applied to more accurately guide treatment of neurodevelopmental diseases, or to identify drugs specifically targeting mutated genes in cancer. A study published in 2015 showed that 28% of hepatocellular carcinomas contained mutated genes that potentially could be targeted by drugs already approved by the US Food and Drug Administration. A translational study, which is described in detail, showed how combined omics, computational, functional and clinical studies could identify and validate a novel diagnostic and therapeutic candidate gene in allergy. Another important clinical implication is the identification of potential diagnostic markers and therapeutic targets for predictive and preventative medicine. By combining computational and experimental methods, early disease regulators may be identified and potentially used to predict and treat disease before it becomes symptomatic. Systems medicine is an emerging discipline, which may contribute to such developments through combining omics with computational, functional and clinical studies. The aims of this review are to provide

  5. Childhood and adolescent sexual behaviors predict adult sexual orientations

    Directory of Open Access Journals (Sweden)

    Keith W. Beard

    2015-12-01

    Full Text Available Anonymous retrospective data were provided by 3,443 adult participants via computer-assisted self-interview. This was the first study focused on determinants of adult sexual orientation to adjust for the effects of same-sex sibling incest. Five measures of adult sexual orientations (ASOs provided evidence consistent with the theory that ASOs result from early sex-specific romantic attachment, conditioning caused by early sexual experiences with partners, and other experiences, such as early masturbation using human images, acting synergistically with critical period learning, and sexual imprinting. Early same-sex crushes were the most powerful predictor of ASOs, and they also increased the likelihood of engaging in early same-sex partnered and masturbation behaviors. Incestuous experiences with same-sex siblings affected the ASOs of the incest participants. And, lesbian, gay, and bisexual participants tended to have an earlier onset of puberty than heterosexual controls within sexes. However, statistical analyses showed that the incest and puberty effects were mathematically explained by the participant’s early sexual experiences with partners and other experiences such as masturbation using human images. Early same-sex crushes were predicted by nuclear family variables implying that same-sex crushes were more likely when the opposite-sex parent modeled an unsatisfactory heterosexual romantic partner.

  6. Predicting sexual coercion in early adulthood: The transaction among maltreatment, gang affiliation, and adolescent socialization of coercive relationship norms.

    Science.gov (United States)

    Ha, Thao; Kim, Hanjoe; Christopher, Caroline; Caruthers, Allison; Dishion, Thomas J

    2016-08-01

    This study tested a transactional hypothesis predicting early adult sexual coercion from family maltreatment, early adolescent gang affiliation, and socialization of adolescent friendships that support coercive relationship norms. The longitudinal study of a community sample of 998 11-year-olds was intensively assessed in early and middle adolescence and followed to 23-24 years of age. At age 16-17 youth were videotaped with a friend, and their interactions were coded for coercive relationship talk. Structural equation modeling revealed that maltreatment predicted gang affiliation during early adolescence. Both maltreatment and gang affiliation strongly predicted adolescent sexual promiscuity and coercive relationship norms with friends at age 16-17 years. Adolescent sexual promiscuity, however, did not predict sexual coercion in early adulthood. In contrast, higher levels of observed coercive relationship talk with a friend predicted sexual coercion in early adulthood for both males and females. These findings suggest that peers have a socialization function in the development of norms prognostic of sexual coercion, and the need to consider peers in the promotion of healthy relationships.

  7. Predicting sexual coercion in early adulthood: The transaction among maltreatment, gang affiliation, and adolescent socialization of coercive relationship norms.

    Science.gov (United States)

    Ha, Thao; Kim, Hanjoe; Christopher, Caroline; Caruthers, Allison; Dishion, Thomas J

    2016-08-01

    This study tested a transactional hypothesis predicting early adult sexual coercion from family maltreatment, early adolescent gang affiliation, and socialization of adolescent friendships that support coercive relationship norms. The longitudinal study of a community sample of 998 11-year-olds was intensively assessed in early and middle adolescence and followed to 23-24 years of age. At age 16-17 youth were videotaped with a friend, and their interactions were coded for coercive relationship talk. Structural equation modeling revealed that maltreatment predicted gang affiliation during early adolescence. Both maltreatment and gang affiliation strongly predicted adolescent sexual promiscuity and coercive relationship norms with friends at age 16-17 years. Adolescent sexual promiscuity, however, did not predict sexual coercion in early adulthood. In contrast, higher levels of observed coercive relationship talk with a friend predicted sexual coercion in early adulthood for both males and females. These findings suggest that peers have a socialization function in the development of norms prognostic of sexual coercion, and the need to consider peers in the promotion of healthy relationships. PMID:27427801

  8. In Eating-Disordered Inpatient Adolescents, Self-Criticism Predicts Nonsuicidal Self-Injury.

    Science.gov (United States)

    Itzhaky, Liat; Shahar, Golan; Stein, Daniel; Fennig, Silvana

    2016-08-01

    We examined the role of depressive traits-self-criticism and dependency-in nonsuicidal self-injury (NSSI) and suicidal ideation among inpatient adolescents with eating disorders. In two studies (N = 103 and 55), inpatients were assessed for depressive traits, suicidal ideations, and NSSI. In Study 2, motivation for carrying out NSSI was also assessed. In both studies, depression predicted suicidal ideation and self-criticism predicted NSSI. In Study 2, depression and suicidal ideation also predicted NSSI. The automatic positive motivation for NSSI was predicted by dependency and depressive symptoms, and by a two-way interaction between self-criticism and dependency. Consistent with the "self-punishment model," self-criticism appears to constitute a dimension of vulnerability for NSSI. PMID:26475665

  9. The Role of Parenting Styles in Predicting Anxiety Thoughts and Obsessive Compulsive Symptoms in Adolescents

    Directory of Open Access Journals (Sweden)

    Z Khanjani

    2012-04-01

    Full Text Available Introduction: Parents interaction styles with children or teens have an important impact on shaping their character and mental health and the incidence of some psychiatric symptoms. The aim of this study was to predict anxiety thought and obsessive - compulsive symptoms of the adolescents based on parents' parenting styles. Methods: This was a descriptive study. 180 male students in Marand were selected by cluster random sampling. We used Baumrind parents parenting style questionnaire, Wales anxiety thoughts questionnaire and Maudsley obsessive- compulsive questionnaire. Data was analyzed by Pearson's correlation test and multiple regression analysis. Results: Data analysis showed that obsessive- compulsive symptoms and anxiety ideas were positively related to the authoritarian and permissive parenting styles and negatively related to authoritative parenting style. Parenting style is able to predict the level of obsessive - compulsive symptoms and adolescent anxiety ideas. Conclusion: The results showed that parents' parenting style is one of the influencing factors on adolescent health. Parents with authoritative parenting style, have the children with lower obsessive - compulsive symptoms and anxious thoughts.

  10. Longitudinal evidence that psychopathy scores in early adolescence predict adult psychopathy.

    Science.gov (United States)

    Lynam, Donald R; Caspi, Avshalom; Moffitt, Terrie E; Loeber, Rolf; Stouthamer-Loeber, Magda

    2007-02-01

    This study examined the relation between psychopathy assessed at age 13 by using the mother-reported Childhood Psychopathy Scale (D. R. Lynam, 1997) and psychopathy assessed at age 24 by using the interviewer-rated Psychopathy Checklist: Screening Version (PCL:SV; S. D. Hart, D. N. Cox, & R. D. Hare, 1995). Data from over 250 participants of the middle sample of the Pittsburgh Youth Study were used to examine this relation; approximately 9% of the sample met criteria for a possible PCL:SV diagnosis. Despite the long time lag, different sources, and different methods, psychopathy from early adolescence into young adulthood was moderately stable (r=.31). The relation was present for the PCL:SV total and facet scores, was not moderated by initial risk status or initial psychopathy level, and held even after controlling for other age 13 variables. Diagnostic stability was somewhat lower. Both specificity and negative predictive power were good, and sensitivity was adequate, but positive predictive power was poor. This constitutes the first demonstration of the relative stability of psychopathy from adolescence into adulthood and provides evidence for the incremental utility of the adolescent psychopathy construct. Implications and future directions are discussed. PMID:17324026

  11. Parental Socialization and Adolescents' Alcohol Use Behaviors: Predictive Disparities in Parents' versus Adolescents' Perceptions of the Parenting Environment

    Science.gov (United States)

    Latendresse, Shawn J.; Rose, Richard J.; Viken, Richard J.; Pulkkinen, Lea; Kaprio, Jaakko; Dick, Danielle M.

    2009-01-01

    Among adolescents, many parenting practices have been associated with the initiation and development of drinking behaviors. However, recent studies suggest discrepancies in parents' and adolescents' perceptions of parenting and their links with adolescent use. In this study, we derive two independent sets of underlying parenting profiles (based on…

  12. Adolescent Alcohol Use: Protective and Predictive Parent, Peer, and Self-Related Factors.

    Science.gov (United States)

    Handren, Lindsay M; Donaldson, Candice D; Crano, William D

    2016-10-01

    Adolescent alcohol use has been linked with a multitude of problems and a trajectory predictive of problematic use in adulthood. Thus, targeting factors that enhance early prevention efforts is vital. The current study highlights variables that mitigate or predict alcohol use and heavy episodic drinking. Using Monitoring the Future (MTF) data, multiple path analytic models revealed links between parental involvement and alcohol abstinence and initiation. Parental involvement predicted enhanced self-esteem and less self-derogation and was negatively associated with peer alcohol norms for each MTF grade sampled, with stronger associations for 8th and 10th graders than 12th graders. For younger groups, self-esteem predicted increased perceptions of alcohol risk and reduced drinking. Self-derogation was associated with peers' pro-alcohol norms, which was linked to lower risk perceptions, lower personal disapproval of use, and increased drinking. Peer influence had a stronger association with consumption for 8th and 10th graders, whereas 12th graders' drinking was related to personal factors of alcohol risk perception and disapproval. In all grades, general alcohol use had a strong connection to heavy episodic drinking within the past 2 weeks. Across-grade variations in association of parent, peer, and personal factors suggest the desirability of tailored interventions focused on specific factors for each grade level, with the overall goal of attenuating adolescent alcohol use. PMID:27562038

  13. Application of Theory of Planned Behavior in Predicting Factors of Substance Abuse in Adolescents

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    Saeid Bashirian

    2012-12-01

    Full Text Available Background and Objective: Adolescence is the most critical period of life as regards commencing drug abuse. The social cost and damage caused by drug abuse in adolescence are enormous, necessitating interventional programs to prevent this behavior. The theory of planned behavior (TPB is perhaps the most influential theory for the prediction of social and health behaviors such as drug abuse.Materials and Methods: In this descriptive analytical study, samples were collected from male students in four high schools in different regions of Hamedan. The survey was carried out via random cluster sampling of 650 students. Data were collected using the standard self-report questionnaires and were analyzed using SPSS16, chi-squared test, correlation coefficient, and logistic regression analysis.Results: Among the adolescents participating in this study, 11.1% had the experience of cigarette smoking, 3.4% had the experience of drug abuse, and 12% had the experience of intention to abuse drugs. There was a significant relationship between drug abuse and the following variables: smoking experience (p value =0.001, OR=27.238; having drug user parents (p value =0.001, OR=8.630; having friends who had experienced drug abuse (p value =0.001, OR=11.060; having best friends who had experienced drug abuse (p value = 0.001, OR=11.931; family with drug abuse (p value = 0.001, OR=4.311; and having a sibling who abused drugs (p value=0.001, OR=15.815. According to the logistic regression analysis, attitude, subjective norms, and perceived behavior control were the most influential predictors of intention to abuse drugs.Conclusion: The use of TPB is beneficial in the predicting and planning for high-risk behaviors. TPB can be used for planning and implementing drug abuse prevention programs in adolescents.

  14. Predicting success or failure of brace treatment for adolescents with idiopathic scoliosis.

    Science.gov (United States)

    Chalmers, Eric; Westover, Lindsey; Jacob, Johith; Donauer, Andreas; Zhao, Vicky H; Parent, Eric C; Moreau, Marc J; Mahood, James K; Hedden, Douglas M; Lou, Edmond H M

    2015-10-01

    Adolescent idiopathic scoliosis (AIS) is a three-dimensional spinal deformity. Brace treatment is a common non-surgical treatment, intended to prevent progression (worsening) of the condition during adolescence. Estimating a braced patient's risk of progression is an essential part of planning treatment, so method for predicting this risk would be a useful decision support tool for practitioners. This work attempts to discover whether failure of brace treatment (progression) can be predicted at the start of treatment. Records were obtained for 62 AIS patients who had completed brace treatment. Subjects were labeled as "progressive" if their condition had progressed despite brace treatment and "non-progressive" otherwise. Wrapper-based feature selection selected two useful predictor variables from a list of 14 clinical measurements taken from the records. A logistic regression model was trained to classify patients as "progressive" or "non-progressive" using these two variables. The logistic regression model's simplicity and interpretability should facilitate its clinical acceptance. The model was tested on data from an additional 28 patients and found to be 75 % accurate. This accuracy is sufficient to make the predictions clinically useful. It can be used online: http://www.ece.ualberta.ca/~dchalmer/SimpleBracePredictor.html . PMID:26002592

  15. Comparison between measured and predicted resting metabolic rate in moderately active adolescents.

    Science.gov (United States)

    De Lorenzo A; Bertini, I; Puijia, A; Testolin, G; Testolin, C

    1999-09-01

    The aim of this study was to check the validity of predictive equations for the calculation of resting metabolic rate (RMR) in moderately active adolescents. The RMR was measured in a sample of 25 healthy 15.5-18.2-year-old boys practicing soccer. The RMR was assessed by indirect calorimetry for 30 min following an overnight fast. Body composition was estimated from skinfold thickness measurements. Among the available equations to predict RMR, we decided to use those a of Molnar et al., Harris-Benedict, Schofield, and Cunningham. Measured and predicted values were compared by means of a one-way ANOVA. Also the Bland-Altman test was performed in order to evaluate the accuracy of the prediction equations compared to the measured value. The measured RMR was found to be 1834 +/- 160 kcal/day (mean +/- SD), while the Molnar et al., Schofield, Harris-Benedict, and Cunningham predicted values were 1707 +/- 78, 1866 +/- 89, 1779 +/- 84 and 1830 +/- 87 kcal/day, respectively. On average, compared to the measured values only the Molnar et al. equation differed significantly. On an individual basis, all the equations demonstrated considerable variability between measured and predicted RMRs. The predicted values also differed significantly. As regards the moderately active subjects (16-18 years old), we recommend the use of the Schofield equation, based on simple anthropometric parameters and also that of Cunningham, even if the estimation or measurement of fat-free mass may be cumbersome for everyday pediatric use. PMID:10664318

  16. Predicting adolescent breakfast consumption in the UK and Australia using an extended theory of planned behaviour.

    Science.gov (United States)

    Mullan, Barbara; Wong, Cara; Kothe, Emily

    2013-03-01

    The aim of this study was to investigate whether the theory of planned behaviour (TPB) with the addition of risk awareness could predict breakfast consumption in a sample of adolescents from the UK and Australia. It was hypothesised that the TPB variables of attitudes, subjective norm and perceived behavioural control (PBC) would significantly predict intentions, and that inclusion of risk perception would increase the proportion of variance explained. Secondly it was hypothesised that intention and PBC would predict behaviour. Participants were recruited from secondary schools in Australia and the UK. A total of 613 participants completed the study (448 females, 165 males; mean=14years ±1.1). The TPB predicted 42.2% of the variance in intentions to eat breakfast. All variables significantly predicted intention with PBC as the strongest component. The addition of risk made a small but significant contribution to the prediction of intention. Together intention and PBC predicted 57.8% of the variance in breakfast consumption. PMID:23219456

  17. Using Cloninger's Temperament Scales to Predict Substance-Related Behaviors in Adolescents: A Prospective Longitudinal Study

    Science.gov (United States)

    Hartman, Christie; Hopfer, Christian; Corley, Robin; Hewitt, John; Stallings, Michael

    2013-01-01

    Background and Objectives We tested one of Cloninger's temperament theories – that high novelty seeking (NS), along with low harm avoidance (HA), reward dependence (RD), and persistence (PE), predicts early-onset substance problems. Methods In a community-based sample of 777 adolescents examined at two time points (mean age 13 and 18, respectively), we examined whether Cloninger's four temperament dimensions at wave 1 predicted five substance-related outcomes at wave 2: age of initiation for cigarettes, alcohol, and illicit drugs, number of substance classes tried, and total number of DSM-IV substance use disorder (SUD) symptoms. Results Cloninger's predicted temperament pattern did significantly predict the number of SUD symptoms at wave 2. For initiation of cigarettes/illicit drugs and number of substance classes tried, HA/NS/PE fit the pattern, but RD did not. For onset of alcohol, only NS and PE fit Cloninger's prediction. Results for NS and PE were most consistent. Conclusions and Scientific Significance Overall, this study provides evidence that Cloninger's theory may hold true for predicting problem use more than for predicting “use” or experimentation. In addition, youth with high novelty seeking and low persistence may find substances especially reinforcing, and identifying these youth and intervening before initiation has occurred may reduce the risk of future substance-related problems. PMID:23617866

  18. Exposure to Violence in the Community Predicts Friendships with Academically Disengaged Peers During Middle Adolescence.

    Science.gov (United States)

    Schwartz, David; Kelly, Brynn M; Mali, Luiza V; Duong, Mylien T

    2016-09-01

    Adolescents who have been exposed to violence in the community often experience subsequent difficulties with academic achievement. Because competence in the classroom is a salient developmental task during the adolescent years, outcomes in this critical context can then have broader implications for social and psychological functioning. In the current study, we tested a hypothesized progression in which the association between violence exposure and deficient achievement is presumed to potentiate friendships with academically disengaged peers. We followed 415 urban adolescents (53 % girls; average age of 14.6 years) for a one-year period, with two annual assessment of psychosocial functioning. Exposure to violence in the community and academic engagement were assessed with a self-report inventory; reciprocated friendships were assessed with a peer interview; and achievement was indexed based on a review of school records. Consistent with our hypotheses, neighborhood violence was associated with deficient classroom achievement. Poor achievement, in turn, mediated associations between community violence exposure and low academic engagement among friends. Our findings highlight pathways though which exposure to community violence potentially predicts later dysfunction. PMID:27138174

  19. Predicting impacts of climate change on medicinal asclepiads of Pakistan using Maxent modeling

    Science.gov (United States)

    Khanum, Rizwana; Mumtaz, A. S.; Kumar, Sunil

    2013-05-01

    Maximum entropy (Maxent) modeling was used to predict the potential climatic niches of three medicinally important Asclepiad species: Pentatropis spiralis, Tylophora hirsuta, and Vincetoxicum arnottianum. All three species are members of the Asclepiad plant family, yet they differ in ecological requirements, biogeographic importance, and conservation value. Occurrence data were collected from herbarium specimens held in major herbaria of Pakistan and two years (2010 and 2011) of field surveys. The Maxent model performed better than random for the three species with an average test AUC value of 0.74 for P. spiralis, 0.84 for V. arnottianum, and 0.59 for T. hirsuta. Under the future climate change scenario, the Maxent model predicted habitat gains for P. spiralis in southern Punjab and Balochistan, and loss of habitat in south-eastern Sindh. Vincetoxicum arnottianum as well as T. hirsuta would gain habitat in upper Peaks of northern parts of Pakistan. T. hirsuta is predicted to lose most of the habitats in northern Punjab and in parches from lower peaks of Galliat, Zhob, Qalat etc. The predictive modeling approach presented here may be applied to other rare Asclepiad species, especially those under constant extinction threat.

  20. The Risk GP Model: the standard model of prediction in medicine.

    Science.gov (United States)

    Fuller, Jonathan; Flores, Luis J

    2015-12-01

    With the ascent of modern epidemiology in the Twentieth Century came a new standard model of prediction in public health and clinical medicine. In this article, we describe the structure of the model. The standard model uses epidemiological measures-most commonly, risk measures-to predict outcomes (prognosis) and effect sizes (treatment) in a patient population that can then be transformed into probabilities for individual patients. In the first step, a risk measure in a study population is generalized or extrapolated to a target population. In the second step, the risk measure is particularized or transformed to yield probabilistic information relevant to a patient from the target population. Hence, we call the approach the Risk Generalization-Particularization (Risk GP) Model. There are serious problems at both stages, especially with the extent to which the required assumptions will hold and the extent to which we have evidence for the assumptions. Given that there are other models of prediction that use different assumptions, we should not inflexibly commit ourselves to one standard model. Instead, model pluralism should be standard in medical prediction.

  1. COMPUTING THERAPY FOR PRECISION MEDICINE: COLLABORATIVE FILTERING INTEGRATES AND PREDICTS MULTI-ENTITY INTERACTIONS.

    Science.gov (United States)

    Regenbogen, Sam; Wilkins, Angela D; Lichtarge, Olivier

    2016-01-01

    Biomedicine produces copious information it cannot fully exploit. Specifically, there is considerable need to integrate knowledge from disparate studies to discover connections across domains. Here, we used a Collaborative Filtering approach, inspired by online recommendation algorithms, in which non-negative matrix factorization (NMF) predicts interactions among chemicals, genes, and diseases only from pairwise information about their interactions. Our approach, applied to matrices derived from the Comparative Toxicogenomics Database, successfully recovered Chemical-Disease, Chemical-Gene, and Disease-Gene networks in 10-fold cross-validation experiments. Additionally, we could predict each of these interaction matrices from the other two. Integrating all three CTD interaction matrices with NMF led to good predictions of STRING, an independent, external network of protein-protein interactions. Finally, this approach could integrate the CTD and STRING interaction data to improve Chemical-Gene cross-validation performance significantly, and, in a time-stamped study, it predicted information added to CTD after a given date, using only data prior to that date. We conclude that collaborative filtering can integrate information across multiple types of biological entities, and that as a first step towards precision medicine it can compute drug repurposing hypotheses. PMID:26776170

  2. Racial and Ethnic Profiles of Complementary and Alternative Medicine Use Among Young Adults in the United States: Findings From the National Longitudinal Study of Adolescent Health.

    Science.gov (United States)

    Upchurch, Dawn M; Wexler Rainisch, Bethany K

    2012-10-01

    This study describes complementary and alternative medicine use among a national sample of young adults, with an emphasis on characterizing racial and ethnic differences, highlighting variation across subgroups of Hispanics. The authors examined young adults ages 18 to 27 years (n = 14 128) from wave III (2001-2002) of the National Longitudinal Study of Adolescent Health. Prevalence estimates and logistic regression results were weighted and adjusted for complex sample design. The study examined recent complementary and alternative medicine use in the past 12 months, recent use for each of 15 specific complementary and alternative medicine modalities, and the 5 most commonly used modalities (herbs, massage, chiropractic, relaxation, and vitamins). Results showed that 29% of young adults aged 18 to 27 years recently used complementary and alternative medicine. Prevalence was highest among Cuban Americans (42%) and lowest among blacks (22%). Young adults used a diversity of complementary and alternative medicine modalities and there were substantial differences in use across racial and ethnic groups.

  3. Childhood internalizing and externalizing problems predict the onset of clinical panic attacks over adolescence: the TRAILS study.

    Directory of Open Access Journals (Sweden)

    Christina M Mathyssek

    Full Text Available BACKGROUND: Panic attacks are a source of individual suffering and are an independent risk factor for later psychopathology. However, much less is known about risk factors for the development of panic attacks, particularly during adolescence when the incidence of panic attacks increases dramatically. We examined whether internalizing and externalizing problems in childhood predict the onset of panic attacks in adolescence. METHOD: This study is part of the TRacking Adolescents' Individual Lives Survey (TRAILS, a Dutch longitudinal population cohort study (N = 1,584. Internalizing and Externalizing Problems were collected using the Youth Self-Report (YSR and the parent-report Child Behavior Checklist (CBCL at baseline (age 10-12. At age 18-20, DSM-IV defined panic attacks since baseline were assessed with the Composite International Diagnostic Interview (CIDI. We investigated whether early adolescent Internalizing and Externalizing Problems predicted panic attacks between ages 10-20 years, using survival analysis in univariate and multivariate models. RESULTS: There were N = 314 (19.8% cases who experienced at least one DSM-IV defined panic attack during adolescence and N = 18 (1.2% who developed panic disorder during adolescence. In univariate analyses, CBCL Total Problems, Internalizing Problems and three of the eight syndrome scales predicted panic attack onset, while on the YSR all broad-band problem scales and each narrow-band syndrome scale predicted panic attack onset. In multivariate analyses, CBCL Social Problems (HR 1.19, p<.05, and YSR Thought Problems (HR 1.15, p<.05 and Social Problems (HR 1.26, p<.01 predicted panic attack onset. CONCLUSION: Risk indicators of panic attack include the wide range of internalizing and externalizing problems. Yet, when adjusted for co-occurring problem behaviors, Social Problems were the most consistent risk factor for panic attack onsets in adolescence.

  4. School Nurses on the Front Lines of Medicine: An Adolescent Female Student with Severe Abdominal Pain.

    Science.gov (United States)

    Olympia, Robert P; Brady, Jodi

    2016-09-01

    Abdominal pain is a common chief complaint encountered by school nurses. This article explains the etiology of abdominal pain in children and adolescents, describes the office assessment, and delineates life-threatening conditions associated with severe abdominal pain that may prompt the school nurse to transfer the student to a local emergency department. PMID:27470683

  5. Exposure to Movie Reckless Driving in Early Adolescence Predicts Reckless, but Not Inattentive Driving.

    Directory of Open Access Journals (Sweden)

    Evelien Kostermans

    Full Text Available We examine the association between exposure to depictions of reckless driving in movies and unsafe driving, modeling inattentive and reckless driving as separate outcomes.Data were obtained by telephone from 1,630 US adolescents aged 10 to 14 years at baseline who were drivers at a survey 6 years later. Exposure to movie reckless driving was measured based on movies seen from a randomly selected list of 50 movie titles that had been content coded for reckless driving among characters. Associations were tested with inattentive and reckless driving behaviors in the subsequent survey-controlling for baseline age, sex, socioeconomic status, parental education, school performance, extracurricular activities, daily television and video/computer game exposure, number of movies watched per week, self-regulation and sensation seeking.Exposure to movie reckless driving was common, with approximately 10% of movie characters having driven recklessly. Confirmatory factor analysis revealed a significant distinction between items tapping reckless and inattentive driving at the 6th wave. Age and exposure to movie reckless driving at baseline were directly associated with wave-6 reckless (but not inattentive driving. Additionally, growth in sensation seeking mediated a prospective relation between the total number of movies watched per week at baseline and reckless driving, independent of exposure to movie reckless driving. Males and high sensation seekers reported lower seatbelt usage and more reckless driving, whereas lower self-regulation predicted inattentive driving.In this study, exposure to movie reckless driving during early adolescence predicted adolescents' reckless driving, suggesting a direct modeling effect. Other aspects of movies were also associated with reckless driving, with that association mediated through growth in sensation seeking. Predictors of reckless driving were different from predictors of inattentive driving, with lower self

  6. Neural correlates of error monitoring in adolescents prospectively predict initiation of tobacco use

    Directory of Open Access Journals (Sweden)

    Andrey P. Anokhin

    2015-12-01

    Full Text Available Deficits in self-regulation of behavior can play an important role in the initiation of substance use and progression to regular use and dependence. One of the distinct component processes of self-regulation is error monitoring, i.e. detection of a conflict between the intended and actually executed action. Here we examined whether a neural marker of error monitoring, Error-Related Negativity (ERN, predicts future initiation of tobacco use. ERN was assessed in a prospective longitudinal sample at ages 12, 14, and 16 using a flanker task. ERN amplitude showed a significant increase with age during adolescence. Reduced ERN amplitude at ages 14 and 16, as well as slower rate of its developmental changes significantly predicted initiation of tobacco use by age 18 but not transition to regular tobacco use or initiation of marijuana and alcohol use. The present results suggest that attenuated development of the neural mechanisms of error monitoring during adolescence can increase the risk for initiation of tobacco use. The present results also suggest that the role of distinct neurocognitive component processes involved in behavioral regulation may be limited to specific stages of addiction.

  7. Predicting violent behavior: The role of violence exposure and future educational aspirations during adolescence.

    Science.gov (United States)

    Stoddard, Sarah A; Heinze, Justin E; Choe, Daniel Ewon; Zimmerman, Marc A

    2015-10-01

    Few researchers have explored future educational aspirations as a promotive factor against exposure to community violence in relation to adolescents' violent behavior over time. The present study examined the direct and indirect effect of exposure to community violence prior to 9th grade on attitudes about violence and violent behavior in 12th grade, and violent behavior at age 22 via 9th grade future educational aspirations in a sample of urban African American youth (n = 681; 49% male). Multi-group SEM was used to test the moderating effect of gender. Exposure to violence was associated with lower future educational aspirations. For boys, attitudes about violence directly predicted violent behavior at age 22. For boys, future educational aspirations indirectly predicted less violent behavior at age 22. Implications of the findings and suggestions for future research are discussed.

  8. Body Fat Equations and Electrical Bioimpedance Values in Prediction of Cardiovascular Risk Factors in Eutrophic and Overweight Adolescents

    Directory of Open Access Journals (Sweden)

    Franciane Rocha Faria

    2013-01-01

    Full Text Available The aim of this study was to analyze body fat anthropometric equations and electrical bioimpedance analysis (BIA in the prediction of cardiovascular risk factors in eutrophic and overweight adolescents. 210 adolescents were divided into eutrophic group (G1 and overweight group (G2. The percentage of body fat (% BF was estimated using 10 body fat anthropometric equations and 2 BIA. We measured lipid profiles, uric acid, insulin, fasting glucose, homeostasis model assessment-insulin resistance (HOMA-IR, and blood pressure. We found that 76.7% of the adolescents exhibited inadequacy of at least one biochemical parameter or clinical cardiovascular risk. Higher values of triglycerides (TG (P=0.001, insulin, and HOMA-IR (P<0.001 were observed in the G2 adolescents. In multivariate linear regression analysis, the % BF from equation (5 was associated with TG, diastolic blood pressure, and insulin in G1. Among the G2 adolescents, the % BF estimated by (5 and (9 was associated with LDL, TG, insulin, and the HOMA-IR. Body fat anthropometric equations were associated with cardiovascular risk factors and should be used to assess the nutritional status of adolescents. In this study, equation (5 was associated with a higher number of cardiovascular risk factors independent of the nutritional status of adolescents.

  9. Forgetting the best when predicting the worst: Preliminary observations on neural circuit function in adolescent social anxiety

    Directory of Open Access Journals (Sweden)

    Johanna M. Jarcho

    2015-06-01

    Full Text Available Social anxiety disorder typically begins in adolescence, a sensitive period for brain development, when increased complexity and salience of peer relationships requires novel forms of social learning. Disordered social learning in adolescence may explain how brain dysfunction promotes social anxiety. Socially anxious adolescents (n = 15 and adults (n = 19 and non-anxious adolescents (n = 24 and adults (n = 32 predicted, then received, social feedback from high and low-value peers while undergoing functional magnetic resonance imaging (fMRI. A surprise recall task assessed memory biases for feedback. Neural correlates of social evaluation prediction errors (PEs were assessed by comparing engagement to expected and unexpected positive and negative feedback. For socially anxious adolescents, but not adults or healthy participants of either age group, PEs elicited heightened striatal activity and negative fronto-striatal functional connectivity. This occurred selectively to unexpected positive feedback from high-value peers and corresponded with impaired memory for social feedback. While impaired memory also occurred in socially-anxious adults, this impairment was unrelated to brain-based PE activity. Thus, social anxiety in adolescence may relate to altered neural correlates of PEs that contribute to impaired learning about social feedback. Small samples necessitate replication. Nevertheless, results suggest that the relationship between learning and fronto-striatal function may attenuate as development progresses.

  10. PREDICTION OF SPORT ADHERENCE THROUGH THE INFLUENCE OF AUTONOMY-SUPPORTIVE COACHING AMONG SPANISH ADOLESCENT ATHLETES

    Directory of Open Access Journals (Sweden)

    Bartolomé J. Almagro

    2010-03-01

    Full Text Available The purpose of this study was to test a motivational model of the coach-athlete relationship, based on self-determination theory and on the hierarchical model of intrinsic and extrinsic motivation. The sample comprised of 608 athletes (ages of 12-17 years completed the following measures: interest in athlete's input, praise for autonomous behavior, perceived autonomy, intrinsic motivation, and the intention to be physically active. Structural equation modeling results demonstrated that interest in athletes' input and praise for autonomous behavior predicted perceived autonomy, and perceived autonomy positively predicted intrinsic motivation. Finally, intrinsic motivation predicted the intention to be physically active in the future. The results are discussed in relation to the importance of the climate of autonomy support created by the coach on intrinsic motivation and adherence to sport by adolescent athletes. Further, the results provide information related to the possible objectives of future interventions for the education of coaches, with the goal of providing them with tools and strategies to favor the development of intrinsic motivation among their athletes. In conclusion, the climate of autonomy support created by the coach can predict the autonomy perceived by the athletes which predicts the intrinsic motivation experienced by the athletes, and therefore, their adherence to athletic practice. Key words: Autonomy support, perceived autonomy, intrinsic motivation, sport adherence

  11. Predicting Social Networking Site Use and Online Communication Practices among Adolescents: The Role of Access and Device Ownership

    Directory of Open Access Journals (Sweden)

    Drew P. Cingel

    2014-06-01

    Full Text Available Given adolescents' heavy social media use, this study examined a number of predictors of adolescent social media use, as well as predictors of online communication practices. Using data collected from a national sample of 467 adolescents between the ages of 13 and 17, results indicate that demographics, technology access, and technology ownership are related to social media use and communication practices. Specifically, females log onto and use more constructive com-munication practices on Facebook compared to males. Additionally, adolescents who own smartphones engage in more constructive online communication practices than those who share regular cell phones or those who do not have access to a cell phone. Overall, results imply that ownership of mobile technologies, such as smartphones and iPads, may be more predictive of social networking site use and online communication practices than general ownership of technology.

  12. Predicting Social Networking Site Use and Online Communication Practices among Adolescents: The Role of Access and Device Ownership

    Directory of Open Access Journals (Sweden)

    Drew P. Cingel

    2014-01-01

    Full Text Available Given adolescents' heavy social media use, this study examined a number of predictors of adolescent social media use, as well as predictors of online communication practices. Using data collected from a national sample of 467 adolescents between the ages of 13 and 17, results indicate that demographics, technology access, and technology ownership are related to social media use and communication practices. Specifically, females log onto and use more constructive communication practices on Facebook compared to males. Additionally, adolescents who own smartphones engage in more constructive online communication practices than those who share regular cell phones or those who do not have access to a cell phone. Overall, results imply that ownership of mobile technologies, such as smartphones and iPads, may be more predictive of social networking site use and online communication practices than general ownership of technology.

  13. Predicting dangerousness with two Millon Adolescent Clinical Inventory psychopathy scales: the importance of egocentric and callous traits.

    Science.gov (United States)

    Salekin, Randall T; Ziegler, Tracey A; Larrea, Maria A; Anthony, Virginia Lee; Bennett, Allyson D

    2003-04-01

    Psychopathy in youth has received increased recognition as a critical clinical construct for the evaluation and management of adolescents who have come into contact with the law (e.g., Forth, Hare, & Hart, 1990; Frick, 1998; Lynam, 1996, 1998). Although considerable attention has been devoted to the adult construct of psychopathy and its relation to recidivism, psychopathy in adolescents has been less thoroughly researched. Recently, a psychopathy scale (Murrie and Cornell Psychopathy Scale; Murrie & Cornell, 2000) was developed from items of the Millon Adolescent Clinical Inventory (MACI; Millon, 1993). This scale was found to be highly related to the Psychopathy Checklist-Revised (Hare, 1991) and was judged to have demonstrated good criterion validity. A necessary step in the validation process of any psychopathy scale is establishing its predictive validity. With this in mind, we investigated the ability of the MACI Psychopathy Scale to predict recidivism with 55 adolescent offenders 2 years after they had been evaluated at a juvenile court evaluation unit. In addition, we devised a psychopathy scale from MACI items that aligned more closely with Cooke and Michie (2001) and Frick, Bodin, and Barry's (2001) recommendations for the refinement of psychopathy and tested its predictive validity. Results indicate that both scales had predictive utility. Interpersonal and affective components of the revised scale were particularly important in the prediction of both general and violent reoffending. PMID:12700018

  14. SCALE DEVELOPMENT FOR MEASURING AND PREDICTING ADOLESCENTS' LEISURE TIME PHYSICAL ACTIVITY BEHAVIOR

    Directory of Open Access Journals (Sweden)

    Silvia Arribas Galarraga

    2009-12-01

    Full Text Available The aim of this study was to develop a scale for assessing and predicting adolescents' physical activity behavior in Spain and Luxembourg using the Theory of Planned Behavior as a framework. The sample was comprised of 613 Spanish (boys = 309, girls = 304; M age =15.28, SD =1.127 and 752 Luxembourgish adolescents (boys = 343, girls = 409; M age = 14.92, SD = 1.198, selected from students of two secondary schools in both countries, with a similar socio-economic status. The initial 43-items were all scored on a 4-point response format using the structured alternative format and translated into Spanish, French and German. In order to ensure the accuracy of the translation, standardized parallel back-translation techniques were employed. Following two pilot tests and subsequent revisions, a second order exploratory factor analysis with oblimin direct rotation was used for factor extraction. Internal consistency and test-retest reliabilities were also tested. The 4-week test-retest correlations confirmed the items' time stability. The same five factors were obtained, explaining 63.76% and 63.64% of the total variance in both samples. Internal consistency for the five factors ranged from α = 0.759 to α = 0. 949 in the Spanish sample and from α = 0.735 to α = 0.952 in the Luxembourgish sample. For both samples, inter-factor correlations were all reported significant and positive, except for Factor 5 where they were significant but negative. The high internal consistency of the subscales, the reported item test-retest reliabilities and the identical factor structure confirm the adequacy of the elaborated questionnaire for assessing the TPB-based constructs when used with a population of adolescents in Spain and Luxembourg. The results give some indication that they may have value in measuring the hypothesized TPB constructs for PA behavior in a cross-cultural context

  15. Re-Visit to the School Nurse and Adolescents' Medicine Use

    Science.gov (United States)

    Borup, Ina K.; Andersen, Anette; Holstein, Bjorn E.

    2011-01-01

    Objective: To examine if students who re-visit the school nurse use medicines differently than other students when exposed to aches and psychological problems. Methods: The study includes all 11-, 13- and 15-year-old students from a random sample of schools in Denmark, response rate 87 per cent, n = 5,205. The data collection followed the…

  16. Adolescents' functional numeracy is predicted by their school entry number system knowledge.

    Science.gov (United States)

    Geary, David C; Hoard, Mary K; Nugent, Lara; Bailey, Drew H

    2013-01-01

    One in five adults in the United States is functionally innumerate; they do not possess the mathematical competencies needed for many modern jobs. We administered functional numeracy measures used in studies of young adults' employability and wages to 180 thirteen-year-olds. The adolescents began the study in kindergarten and participated in multiple assessments of intelligence, working memory, mathematical cognition, achievement, and in-class attentive behavior. Their number system knowledge at the beginning of first grade was defined by measures that assessed knowledge of the systematic relations among Arabic numerals and skill at using this knowledge to solve arithmetic problems. Early number system knowledge predicted functional numeracy more than six years later (ß = 0.195, p = .0014) controlling for intelligence, working memory, in-class attentive behavior, mathematical achievement, demographic and other factors, but skill at using counting procedures to solve arithmetic problems did not. In all, we identified specific beginning of schooling numerical knowledge that contributes to individual differences in adolescents' functional numeracy and demonstrated that performance on mathematical achievement tests underestimates the importance of this early knowledge. PMID:23382934

  17. Adolescents' functional numeracy is predicted by their school entry number system knowledge.

    Directory of Open Access Journals (Sweden)

    David C Geary

    Full Text Available One in five adults in the United States is functionally innumerate; they do not possess the mathematical competencies needed for many modern jobs. We administered functional numeracy measures used in studies of young adults' employability and wages to 180 thirteen-year-olds. The adolescents began the study in kindergarten and participated in multiple assessments of intelligence, working memory, mathematical cognition, achievement, and in-class attentive behavior. Their number system knowledge at the beginning of first grade was defined by measures that assessed knowledge of the systematic relations among Arabic numerals and skill at using this knowledge to solve arithmetic problems. Early number system knowledge predicted functional numeracy more than six years later (ß = 0.195, p = .0014 controlling for intelligence, working memory, in-class attentive behavior, mathematical achievement, demographic and other factors, but skill at using counting procedures to solve arithmetic problems did not. In all, we identified specific beginning of schooling numerical knowledge that contributes to individual differences in adolescents' functional numeracy and demonstrated that performance on mathematical achievement tests underestimates the importance of this early knowledge.

  18. Risk score for predicting adolescent mental health problems among children using parental report only : the TRAILS study

    NARCIS (Netherlands)

    Burger, Huibert; Boks, Marco P.; Hartman, Catharina A.; Aukes, Maartje F.; Verhulst, Frank C.; Ormel, Johan; Reijneveld, Sijmen A.

    2014-01-01

    OBJECTIVE: To construct a risk score for adolescent mental health problems among children, using parental data only and without potentially stigmatizing mental health items. METHODS: We prospectively derived a prediction model for mental health problems at age 16 using data from parent report on 167

  19. Predicting the Filial Behaviors of Chinese-Malaysian Adolescents from Perceived Parental Investments, Filial Emotions, and Parental Warmth and Support

    Science.gov (United States)

    Cheah, Charissa S. L.; Ozdemir, Sevgi Bayram; Leung, Christy Y. Y.

    2012-01-01

    The present study examined the mediating role of perceived parental warmth and support in predicting Chinese Malaysian adolescents' filial behaviors from their age, perceived parental investments, and positive filial emotions toward their parents. The effects of these predictors were examined separately for mothers and fathers. Participants…

  20. Survival outcomes scores (SOFT, BAR, and Pedi-SOFT) are accurate in predicting post-liver transplant survival in adolescents.

    Science.gov (United States)

    Conjeevaram Selvakumar, Praveen Kumar; Maksimak, Brian; Hanouneh, Ibrahim; Youssef, Dalia H; Lopez, Rocio; Alkhouri, Naim

    2016-09-01

    SOFT and BAR scores utilize recipient, donor, and graft factors to predict the 3-month survival after LT in adults (≥18 years). Recently, Pedi-SOFT score was developed to predict 3-month survival after LT in young children (≤12 years). These scoring systems have not been studied in adolescent patients (13-17 years). We evaluated the accuracy of these scoring systems in predicting the 3-month post-LT survival in adolescents through a retrospective analysis of data from UNOS of patients aged 13-17 years who received LT between 03/01/2002 and 12/31/2012. Recipients of combined organ transplants, donation after cardiac death, or living donor graft were excluded. A total of 711 adolescent LT recipients were included with a mean age of 15.2±1.4 years. A total of 100 patients died post-LT including 33 within 3 months. SOFT, BAR, and Pedi-SOFT scores were all found to be good predictors of 3-month post-transplant survival outcome with areas under the ROC curve of 0.81, 0.80, and 0.81, respectively. All three scores provided good accuracy for predicting 3-month survival post-LT in adolescents and may help clinical decision making to optimize survival rate and organ utilization. PMID:27478012

  1. Low socioeconomic status predicts abnormal eating attitudes in Latin American female adolescents.

    Science.gov (United States)

    Power, Yuri; Power, Lorena; Canadas, Maria Beatriz

    2008-01-01

    The objective of this study was to study the proportion of Ecuadorian students fulfilling criteria on the Eating Attitudes Test (EAT) in relation to socioeconomic status. Seven hundred and twenty three female adolescent participants recruited from Quito, Ecuador were administered a brief questionnaire consisting of the EAT-40 as well as lifestyle questions. Mean EAT-40 score was 17.12, with 14% fulfilling criteria. Lower socioeconomic status and watching more television predicted higher scores; however BMI, age, and positive smoking status failed to correlate. The presently unvalidated Spanish version of the EAT-26 highly correlated with the validated EAT-40 (R=0.94). A higher than expected proportion of Ecuadorians are at risk for eating disorders, especially among lower socioeconomic groups. The EAT-26 should be considered for validation as a primary screening tool in Latin America. PMID:18307113

  2. Consultation for Disordered Puberty: What Do Adolescent Medicine Patients Teach Us?

    Science.gov (United States)

    Michaud, Pierre-André; Ambresin, Anne-Emmanuelle

    2016-01-01

    The period of adolescence is not only marked by important growth and pubertal events, but is also characterized by important psychosocial changes driven by a search for autonomy and the construction of one's identity. It can thus be easily understood that puberty disorders interfere heavily with these process, requiring from the endocrinologist not only medical knowledge, but also a great deal of emotional and psychological skills. They must progressively move from an educational approach that heavily involves the parents to one of shared information and decision making that places the young patient at the center of the therapeutic process. This can be achieved in several ways: respecting the affective and cognitive development of the adolescent; securing his privacy and (if requested by him) confidentiality; exploring his self-image and self-esteem and adapting the therapeutic process to the patient's expectations; reviewing the teenager's lifestyle, including the issue of sexuality and sexual behavior, and involving him in any therapeutic choice that has to be made, even if it does not match with the parents' expectations. The skills required for this respectful and holistic follow-up often exceed the abilities of any physician; it is thus suggested that a team approach involving a clinical nurse and/or a psychologist and/or social worker(s) be set up whenever possible. PMID:26680583

  3. Consultation for Disordered Puberty: What Do Adolescent Medicine Patients Teach Us?

    Science.gov (United States)

    Michaud, Pierre-André; Ambresin, Anne-Emmanuelle

    2016-01-01

    The period of adolescence is not only marked by important growth and pubertal events, but is also characterized by important psychosocial changes driven by a search for autonomy and the construction of one's identity. It can thus be easily understood that puberty disorders interfere heavily with these process, requiring from the endocrinologist not only medical knowledge, but also a great deal of emotional and psychological skills. They must progressively move from an educational approach that heavily involves the parents to one of shared information and decision making that places the young patient at the center of the therapeutic process. This can be achieved in several ways: respecting the affective and cognitive development of the adolescent; securing his privacy and (if requested by him) confidentiality; exploring his self-image and self-esteem and adapting the therapeutic process to the patient's expectations; reviewing the teenager's lifestyle, including the issue of sexuality and sexual behavior, and involving him in any therapeutic choice that has to be made, even if it does not match with the parents' expectations. The skills required for this respectful and holistic follow-up often exceed the abilities of any physician; it is thus suggested that a team approach involving a clinical nurse and/or a psychologist and/or social worker(s) be set up whenever possible.

  4. Thyroid cancer in children and adolescents of Belarus irradiated as a result of Chernobyl accident: status and prediction

    International Nuclear Information System (INIS)

    Thyroid cancer incidence in the human population of Belarus irradiated in childhood for the period passed after the Chernobyl accident is analysed and potential perspectives for development of disease incidence in exposed population during life span. Thyroid cancer cases in children and adolescents of Belarus irradiated due to the Chernobyl accident are predicted using the additive model with modified parameters. Predicted values are shown to be in good agreement with the actual data on thyroid cancer cases in children aged 0-6

  5. Complementary and alternative medicine use in adolescents with inflammatory bowel disease and juvenile idiopathic arthritis

    OpenAIRE

    Nousiainen, Pauliina; Merras-Salmio, Laura; Aalto, Kristiina; Kolho, Kaija-Leena

    2014-01-01

    Background The use of complementary alternative medicine (CAM) is potentially prevalent among paediatric patients with chronic diseases but with variable rates among different age groups, diseases and countries. There are no recent reports on CAM use among paediatric patients with inflammatory bowel disease (IBD) and juvenile idiopathic arthritis (JIA) in Europe. We hypothesized that CAM use associates with a more severe disease in paediatric IBD and JIA. Methods A cross-sectional questionnai...

  6. Within-Person Changes in Individual Symptoms of Depression Predict Subsequent Depressive Episodes in Adolescents: a Prospective Study.

    Science.gov (United States)

    Kouros, Chrystyna D; Morris, Matthew C; Garber, Judy

    2016-04-01

    The current longitudinal study examined which individual symptoms of depression uniquely predicted a subsequent Major Depressive Episode (MDE) in adolescents, and whether these relations differed by sex. Adolescents (N = 240) were first interviewed in grade 6 (M = 11.86 years old; SD = 0.56; 54% female; 81.5% Caucasian) and then annually through grade 12 regarding their individual symptoms of depression as well as the occurrence of MDEs. Individual symptoms of depression were assessed with the Children's Depression Rating Scale-Revised (CDRS-R) and depressive episodes were assessed with the Longitudinal Interval Follow-up Evaluation (LIFE). Results showed that within-person changes in sleep problems and low self-esteem/excessive guilt positively predicted an increased likelihood of an MDE for both boys and girls. Significant sex differences also were found. Within-person changes in anhedonia predicted an increased likelihood of a subsequent MDE among boys, whereas irritability predicted a decreased likelihood of a future MDE among boys, and concentration difficulties predicted a decreased likelihood of an MDE in girls. These results identified individual depressive symptoms that predicted subsequent depressive episodes in male and female adolescents, and may be used to guide the early detection, treatment, and prevention of depressive disorders in youth. PMID:26105209

  7. Life stress in adolescence predicts early adult reward-related brain function and alcohol dependence

    OpenAIRE

    Casement, Melynda D.; Shaw, Daniel S.; Sitnick, Stephanie L.; Musselman, Samuel C.; Forbes, Erika E.

    2014-01-01

    Stressful life events increase vulnerability to problematic alcohol use, and they may do this by disrupting reward-related neural circuitry. This is particularly relevant for adolescents because alcohol use rises sharply after mid-adolescence and alcohol abuse peaks at age 20. Adolescents also report more stressors compared with children, and neural reward circuitry may be especially vulnerable to stressors during adolescence because of prefrontal cortex remodeling. Using a large sample of ma...

  8. The Role of Peer Group Aggression in Predicting Adolescent Dating Violence and Relationship Quality

    Science.gov (United States)

    Ellis, Wendy E.; Chung-Hall, Janet; Dumas, Tara M.

    2013-01-01

    Past research has shown that adolescent peer groups make a significant contribution to shaping behavior but less is known about the role of peer groups in adolescent dating relationships. This longitudinal study examined the contribution of aggressive peer group norms on relationship quality and dating violence among dating adolescents. At the…

  9. Processing Speed and Neurodevelopment in Adolescent-Onset Psychosis: Cognitive Slowing Predicts Social Function

    Science.gov (United States)

    Bachman, Peter; Niendam, Tara A.; Jalbrzikowkski, Maria; Park, Chan Y.; Daley, Melita; Cannon, Tyrone D.; Bearden, Carrie E.

    2012-01-01

    Onset of psychosis may be associated with abnormal adolescent neurodevelopment. Here we examined the neurocognitive profile of first-episode, adolescent onset psychosis (AOP) as compared to typically developing adolescents, and asked whether neurocognitive performance varied differentially as a function of age in the cases compared with controls.…

  10. Adolescent Eating Disorders Predict Psychiatric, High-Risk Behaviors and Weight Outcomes in Young Adulthood

    Science.gov (United States)

    Micali, Nadia; Solmi, Francesca; Horton, Nicholas J.; Crosby, Ross D.; Eddy, Kamryn T.; Calzo, Jerel P.; Sonneville, Kendrin R.; Swanson, Sonja A.; Field, Alison E.

    2015-01-01

    Objective To investigate whether anorexia nervosa (AN), bulimia nervosa (BN), binge eating disorder (BED), and other specified feeding and eating disorders (OSFED), including purging disorder (PD), subthreshold BN, and BED at ages 14 and 16, are prospectively associated with later depression, anxiety disorders, alcohol and substance use, and self-harm. Method Eating disorders were ascertained at 14 and 16 years of age in 6,140 youth at age 14 (58% of those eligible) and 5,069 at age 16 (52% of those eligible) as part of the prospective Avon Longitudinal Study of Parents and Children (ALSPAC). Outcomes (depression, anxiety disorders, binge drinking, drug use, deliberate self-harm, weight status) were measured using interviews and questionnaires about 2 years following predictors. Generalized estimating equation models adjusting for gender, socio-demographic variables, and prior outcome were used to examine prospective associations between eating disorders and each outcome. Results All eating disorders were predictive of later anxiety disorders. AN, BN, BED, PD, and OSFED were prospectively associated with depression (respectively AN: odds ratio [OR]=1.39 [95% CIs: 1.00-1.94]; BN: OR=3.39[1.25-9.20]; BED: OR=2.00 [1.06-3.75]; PD: OR=2.56 [1.38-4.74]). All eating disorders but AN predicted drug use and deliberate self-harm (BN: OR=5.72[2.22-14.72], PD: OR=4.88[2.78-8.57], subthreshold BN: OR=3.97[1.44-10.98], subthreshold BED: OR=2.32[1.43-3.75]). Whilst BED and BN predicted obesity (respectively OR=3.58 [1.06-12.14] and OR=6.42 [1.69-24.30]), AN was prospectively associated with underweight. Conclusions Adolescent eating disorders, including subthreshold presentations, predict negative outcomes, including mental health disorders, substance use, deliberate self-harm, and weight outcomes. This study highlights the high public health and clinical burden of eating disorders among adolescents. PMID:26210334

  11. Are adolescents with internet addiction prone to aggressive behavior? The mediating effect of clinical comorbidities on the predictability of aggression in adolescents with internet addiction.

    Science.gov (United States)

    Lim, Jae-A; Gwak, Ah Reum; Park, Su Mi; Kwon, Jun-Gun; Lee, Jun-Young; Jung, Hee Yeon; Sohn, Bo Kyung; Kim, Jae-Won; Kim, Dai Jin; Choi, Jung-Seok

    2015-05-01

    Previous studies have reported associations between aggression and Internet addiction disorder (IAD), which has also been linked with anxiety, depression, and impulsiveness. However, the causal relationship between aggression and IAD has thus far not been clearly demonstrated. This study was designed to (a) examine the association between aggression and IAD and (b) investigate the mediating effects of anxiety, depression, and impulsivity in cases in which IAD predicts aggression or aggression predicts IAD. A total of 714 middle school students in Seoul, South Korea, were asked to provide demographic information and complete the Young's Internet Addiction Test (Y-IAT), the Buss-Perry Aggression Questionnaire, the Barratt Impulsiveness Scale-11, the State-Trait Anger Expression Inventory-2, the Beck Anxiety Inventory, the Beck Depression Inventory, and the Conners-Wells Adolescent Self-Report Scale. Three groups were identified based on the Y-IAT: the usual user group (n=487, 68.2%), the high-risk group (n=191, 26.8%), and the Internet addiction group (n=13, 1.8%). The data revealed a linear association between aggression and IAD such that one variable could be predicted by the other. According to the path analysis, the clinical scales (BAI, BDI, and CASS) had partial or full mediating effects on the ability of aggression to predict IAD, but the clinical scales had no mediating effect on the ability of IAD to predict aggression. The current findings suggest that adolescents with IAD seem to have more aggressive dispositions than do normal adolescents. If more aggressive individuals are clinically prone to Internet addiction, early psychiatric intervention may contribute to the prevention of IAD. PMID:25902276

  12. Are adolescents with internet addiction prone to aggressive behavior? The mediating effect of clinical comorbidities on the predictability of aggression in adolescents with internet addiction.

    Science.gov (United States)

    Lim, Jae-A; Gwak, Ah Reum; Park, Su Mi; Kwon, Jun-Gun; Lee, Jun-Young; Jung, Hee Yeon; Sohn, Bo Kyung; Kim, Jae-Won; Kim, Dai Jin; Choi, Jung-Seok

    2015-05-01

    Previous studies have reported associations between aggression and Internet addiction disorder (IAD), which has also been linked with anxiety, depression, and impulsiveness. However, the causal relationship between aggression and IAD has thus far not been clearly demonstrated. This study was designed to (a) examine the association between aggression and IAD and (b) investigate the mediating effects of anxiety, depression, and impulsivity in cases in which IAD predicts aggression or aggression predicts IAD. A total of 714 middle school students in Seoul, South Korea, were asked to provide demographic information and complete the Young's Internet Addiction Test (Y-IAT), the Buss-Perry Aggression Questionnaire, the Barratt Impulsiveness Scale-11, the State-Trait Anger Expression Inventory-2, the Beck Anxiety Inventory, the Beck Depression Inventory, and the Conners-Wells Adolescent Self-Report Scale. Three groups were identified based on the Y-IAT: the usual user group (n=487, 68.2%), the high-risk group (n=191, 26.8%), and the Internet addiction group (n=13, 1.8%). The data revealed a linear association between aggression and IAD such that one variable could be predicted by the other. According to the path analysis, the clinical scales (BAI, BDI, and CASS) had partial or full mediating effects on the ability of aggression to predict IAD, but the clinical scales had no mediating effect on the ability of IAD to predict aggression. The current findings suggest that adolescents with IAD seem to have more aggressive dispositions than do normal adolescents. If more aggressive individuals are clinically prone to Internet addiction, early psychiatric intervention may contribute to the prevention of IAD.

  13. A prognostic model predicting autologous transplantation outcomes in children, adolescents and young adults with Hodgkin lymphoma.

    Science.gov (United States)

    Satwani, P; Ahn, K W; Carreras, J; Abdel-Azim, H; Cairo, M S; Cashen, A; Chen, A I; Cohen, J B; Costa, L J; Dandoy, C; Fenske, T S; Freytes, C O; Ganguly, S; Gale, R P; Ghosh, N; Hertzberg, M S; Hayashi, R J; Kamble, R T; Kanate, A S; Keating, A; Kharfan-Dabaja, M A; Lazarus, H M; Marks, D I; Nishihori, T; Olsson, R F; Prestidge, T D; Rolon, J M; Savani, B N; Vose, J M; Wood, W A; Inwards, D J; Bachanova, V; Smith, S M; Maloney, D G; Sureda, A; Hamadani, M

    2015-11-01

    Autologous hematopoietic cell transplantation (AutoHCT) is a potentially curative treatment modality for relapsed/refractory Hodgkin lymphoma (HL). However, no large studies have evaluated pretransplant factors predictive of outcomes of AutoHCT in children, adolescents and young adults (CAYA, age <30 years). In a retrospective study, we analyzed 606 CAYA patients (median age 23 years) with relapsed/refractory HL who underwent AutoHCT between 1995 and 2010. The probabilities of PFS at 1, 5 and 10 years were 66% (95% confidence interval (CI): 62-70), 52% (95% CI: 48-57) and 47% (95% CI: 42-51), respectively. Multivariate analysis for PFS demonstrated that at the time of AutoHCT patients with Karnofsky/Lansky score ⩾90, no extranodal involvement and chemosensitive disease had significantly improved PFS. Patients with time from diagnosis to first relapse of <1 year had a significantly inferior PFS. A prognostic model for PFS was developed that stratified patients into low-, intermediate- and high-risk groups, predicting for 5-year PFS probabilities of 72% (95% CI: 64-80), 53% (95% CI: 47-59) and 23% (95% CI: 9-36), respectively. This large study identifies a group of CAYA patients with relapsed/refractory HL who are at high risk of progression after AutoHCT. Such patients should be targeted for novel therapeutic and/or maintenance approaches post-AutoHCT. PMID:26237164

  14. Parent-child math anxiety and math-gender stereotypes predict adolescents' math education outcomes.

    Science.gov (United States)

    Casad, Bettina J; Hale, Patricia; Wachs, Faye L

    2015-01-01

    Two studies examined social determinants of adolescents' math anxiety including parents' own math anxiety and children's endorsement of math-gender stereotypes. In Study 1, parent-child dyads were surveyed and the interaction between parent and child math anxiety was examined, with an eye to same- and other-gender dyads. Results indicate that parent's math anxiety interacts with daughters' and sons' anxiety to predict math self-efficacy, GPA, behavioral intentions, math attitudes, and math devaluing. Parents with lower math anxiety showed a positive relationship to children's math outcomes when children also had lower anxiety. The strongest relationships were found with same-gender dyads, particularly Mother-Daughter dyads. Study 2 showed that endorsement of math-gender stereotypes predicts math anxiety (and not vice versa) for performance beliefs and outcomes (self-efficacy and GPA). Further, math anxiety fully mediated the relationship between gender stereotypes and math self-efficacy for girls and boys, and for boys with GPA. These findings address gaps in the literature on the role of parents' math anxiety in the effects of children's math anxiety and math anxiety as a mechanism affecting performance. Results have implications for interventions on parents' math anxiety and dispelling gender stereotypes in math classrooms.

  15. Adolescent sexuality in the limelight. Study and predictability of condom use through the theory of planned behaviour

    Directory of Open Access Journals (Sweden)

    Eufrosini Barmpagianni

    2011-04-01

    Full Text Available Adolescents' sexual behavior is the focus of attention since increased levels of unintended pregnancy, abortions and sexually transmitted diseases are detected. Psychological, family and social factors contribute to the above mentioned situations. The aim of the present research was to examine the intention of condom use in adolescents of both sexes using the Theory of Planned Behavior. Material- Method: The study population consisted of 378 adolescents, aged 15 to 18. Data was collected by the completion of a questionnaire based on the Theory of Planned Behavior. The statistical method used was x2, t-test, one-way ANOVA. The data statistical analysis was carried out using the SPSS 13.0 program. Results: From the participants, 94.9% reported that they had sufficient knowledge on contraception issues. Friends were the main source of information (20.2%. The majority of adolescents (58.2% had full sexual intercourse at age 15 (30%. Proportionally, adolescents with higher self-efficacy were found to have greater intention to the condom use. The more increased was the degree of the convenience in using condom with a new partner, the more positive was the adolescents' attitude towards the use of condom with a steady partner and the greater was the degree of awareness about sexual issues, the greater the behavioral intention. Conclusions: The degree of the adolescents' self-efficacy, in other words, the more confident they are in their abilities and skills of overcoming possible obstacles, the greater their intention to use condom. According to the results, the factors which strongly predict the intention, in order of importance, were: self – efficacy, degree of control, degree of awareness and the descriptive regularity. The findings are of great importance for the Hellenic science, since there is insufficient and little data on this subject.

  16. Amygdala response predicts trajectory of symptom reduction during Trauma-Focused Cognitive-Behavioral Therapy among adolescent girls with PTSD.

    Science.gov (United States)

    Cisler, Josh M; Sigel, Benjamin A; Kramer, Teresa L; Smitherman, Sonet; Vanderzee, Karin; Pemberton, Joy; Kilts, Clinton D

    2015-12-01

    Trauma-Focused Cognitive-Behavioral Therapy (TF-CBT) is the gold standard treatment for pediatric PTSD. Nonetheless, clinical outcomes in TF-CBT are highly variable, indicating a need to identify reliable predictors that allow forecasting treatment response. Here, we test the hypothesis that functional neuroimaging correlates of emotion processing predict PTSD symptom reduction during Trauma-Focused Cognitive-Behavioral Therapy (TF-CBT) among adolescent girls with PTSD. Thirty-four adolescent girls with PTSD related to physical or sexual assault were enrolled in TF-CBT, delivered in an approximately 12 session format, in an open trial. Prior to treatment, they were engaged in an implicit threat processing task during 3T fMRI, during which they viewed faces depicting fearful or neutral expressions. Among adolescent girls completing TF-CBT (n = 23), slopes of PTSD symptom trajectories during TF-CBT were significantly related to pre-treatment degree of bilateral amygdala activation while viewing fearful vs neutral images. Adolescents with less symptom reduction were characterized by greater amygdala activation to both threat and neutral images (i.e., less threat-safety discrimination), whereas adolescents with greater symptom reduction were characterized by amygdala activation only to threat images. These clinical outcome relationships with pre-treatment bilateral amygdala activation remained when controlling for possible confounding demographic or clinical variables (e.g., concurrent psychotropic medication, comorbid diagnoses). While limited by a lack of a control group, these preliminary results suggest that pre-treatment amygdala reactivity to fear stimuli, a component of neurocircuitry models of PTSD, positively predicts symptom reduction during TF-CBT among assaulted adolescent girls, providing support for an objective measure for forecasting treatment response in this vulnerable population.

  17. Longer Weekly Sleep Duration Predicts Greater 3-Month BMI Reduction among Obese Adolescents Attending a Clinical Multidisciplinary Weight Management Program

    Directory of Open Access Journals (Sweden)

    Bethany J. Sallinen

    2013-05-01

    Full Text Available Aims: To determine whether baseline levels of self-reported sleep and sleep problems among obese adolescents referred to an outpatient multidisciplinary family-based weight management program predict reduction in BMI 3 months later. Methods: A retrospective medical chart review was conducted for 83 obese adolescents. The following baseline variables were extracted: self-reported sleep duration (weekdays and weekends, and presence of snoring, daytime fatigue, suspected sleep apnea, and physician-diagnosed sleep apnea. Anthropometric data at baseline and 3 months were also collected. Results: On average, adolescents reported significantly less sleeping on weeknights (7.7 ± 1.3 h compared to weekend nights (10.0 ± 1.8 h, t(82 = 10.5, p = 0.0001. Reduction in BMI after 3 months of treatment was predicted by more weekly sleep at baseline (R2 = 0.113, F(1, 80 = 10.2, p = 0.002. Adolescents who reduced their BMI by ≥1 kg/m2 reported greater weekly sleep at baseline compared to adolescents who experienced 2 reduction (60.7 ± 7.5 h vs. 56.4 ± 8.6 h; F(1, 80 = 5.7, p = 0.02. Conclusion: Findings from this study, though correlational, raise the possibility that increased duration of sleep may be associated with weight loss among obese adolescents enrolled in a weight management program. Evidence-based behavioral techniques to improve sleep hygiene and increase sleep duration should be explored in pediatric weight management settings.

  18. Accuracy of Prediction Equations to Assess Percentage of Body Fat in Children and Adolescents with Down Syndrome Compared to Air Displacement Plethysmography

    Science.gov (United States)

    Gonzalez-Aguero, A.; Vicente-Rodriguez, G.; Ara, I.; Moreno, L. A.; Casajus, J. A.

    2011-01-01

    To determine the accuracy of the published percentage body fat (%BF) prediction equations (Durnin et al., Johnston et al., Brook and Slaughter et al.) from skinfold thickness compared to air displacement plethysmography (ADP) in children and adolescents with Down syndrome (DS). Twenty-eight children and adolescents with DS (10-20 years old; 12…

  19. Development and cross-validation of prediction equations for estimating resting energy expenditure in severely obese Caucasian children and adolescents.

    Science.gov (United States)

    Lazzer, Stefano; Agosti, Fiorenza; De Col, Alessandra; Sartorio, Alessandro

    2006-11-01

    The objectives of the present study were to develop and cross-validate new equations for predicting resting energy expenditure (REE) in severely obese children and adolescents, and to determine the accuracy of new equations using the Bland-Altman method. The subjects of the study were 574 obese Caucasian children and adolescents (mean BMI z-score 3.3). REE was determined by indirect calorimetry and body composition by bioelectrical impedance analysis. Equations were derived by stepwise multiple regression analysis using a calibration cohort of 287 subjects and the equations were cross-validated in the remaining 287 subjects. Two new specific equations based on anthropometric parameters were generated as follows: (1) REE=(Sex x 892.68)-(Age x 115.93)+(Weight x 54.96)+(Stature x 1816.23)+1484.50 (R(2) 0.66; se 1028.97 kJ); (2) REE=(Sex x 909.12)-(Age x 107.48)+(fat-free mass x 68.39)+(fat mass x 55.19)+3631.23 (R(2) 0.66; se 1034.28 kJ). In the cross-validation group, mean predicted REE values were not significantly different from the mean measured REE for all children and adolescents, as well as for boys and for girls (difference <2 %) and the limits of agreement (+/-2 sd) were +2.06 and -1.77 MJ/d (NS). The new prediction equations allow an accurate estimation of REE in groups of severely obese children and adolescents. These equations might be useful for health care professionals and researchers when estimating REE in severely obese children and adolescents. PMID:17092390

  20. Non-suicidal self-injury prospectively predicts interpersonal stressful life events and depressive symptoms among adolescent girls.

    Science.gov (United States)

    Burke, Taylor A; Hamilton, Jessica L; Abramson, Lyn Y; Alloy, Lauren B

    2015-08-30

    Non-suicidal self-injury (NSSI) is the deliberate self-harm of one's tissue, engaged in without lethal intent, and occurs frequently among late adolescents. Although research has indicated that NSSI predicts depression, the potential psychosocial mechanisms through which engagement in NSSI makes one susceptible to future depressive symptoms remain unclear. The present study examined whether NSSI increases the risk of experiencing stressful life events, which, in turn, heightens the risk for subsequent depressive symptoms. Drawn from a sample specifically selected for adolescents at high and low risk for developing bipolar spectrum disorders, a total of 110 late-adolescents (mean age=18.74, SD=.69; 73% female) were administered measures of lifetime and past year engagement in NSSI and current depressive symptomatology. Approximately 6 months later, they completed a measure of depressive symptoms and a questionnaire and interview assessing life events that occurred over the 6-month interval. Results suggest that the frequency of lifetime and past year NSSI predicted the occurrence of interpersonal stressful life events beyond the effects of initial depressive symptoms, but only for late adolescent girls. Results further suggest that higher levels of interpersonal stressful life events mediated the relationship between NSSI frequency and prospective increases in depressive symptoms among girls.

  1. Validation of a multifactorial risk factor model used for predicting future caries risk with nevada adolescents

    Directory of Open Access Journals (Sweden)

    Mobley Connie

    2011-05-01

    Full Text Available Abstract Background The objective of this study was to measure the validity and reliability of a multifactorial Risk Factor Model developed for use in predicting future caries risk in Nevada adolescents in a public health setting. Methods This study examined retrospective data from an oral health surveillance initiative that screened over 51,000 students 13-18 years of age, attending public/private schools in Nevada across six academic years (2002/2003-2007/2008. The Risk Factor Model included ten demographic variables: exposure to fluoridation in the municipal water supply, environmental smoke exposure, race, age, locale (metropolitan vs. rural, tobacco use, Body Mass Index, insurance status, sex, and sealant application. Multiple regression was used in a previous study to establish which significantly contributed to caries risk. Follow-up logistic regression ascertained the weight of contribution and odds ratios of the ten variables. Researchers in this study computed sensitivity, specificity, positive predictive value (PVP, negative predictive value (PVN, and prevalence across all six years of screening to assess the validity of the Risk Factor Model. Results Subjects' overall mean caries prevalence across all six years was 66%. Average sensitivity across all six years was 79%; average specificity was 81%; average PVP was 89% and average PVN was 67%. Conclusions Overall, the Risk Factor Model provided a relatively constant, valid measure of caries that could be used in conjunction with a comprehensive risk assessment in population-based screenings by school nurses/nurse practitioners, health educators, and physicians to guide them in assessing potential future caries risk for use in prevention and referral practices.

  2. Women's higher health risks in the obesogenic environment: a gender nutrition approach to metabolic dimorphism with predictive, preventive, and personalised medicine

    Directory of Open Access Journals (Sweden)

    Shapira Niva

    2013-01-01

    Full Text Available Abstract Women's evolution for nurturing and fat accumulation, which historically yielded health and longevity advantages against scarcity, may now be counteracted by increasing risks in the obesogenic environment, recently shown by narrowing gender health gap. Women's differential metabolism/disease risks, i.e. in fat accumulation/distribution, exemplified during puberty/adolescence, suggest gender dimorphism with obesity outcomes. Women's higher body fat percentage than men, even with equal body mass index, may be a better risk predictor. Differential metabolic responses to weight-reduction diets, with women's lower abdominal fat loss, better response to high-protein vs. high-carbohydrate diets, higher risks with sedentariness vs. exercise benefits, and tendency toward delayed manifestation of central obesity, metabolic syndrome, diabetes, cardiovascular disease, and certain cancers until menopause—but accelerated thereafter—suggest a need for differing metabolic and chronological perspectives for prevention/intervention. These perspectives, including women's differential responses to lifestyle changes, strongly support further research with a gender nutrition emphasis within predictive, preventive, and personalized medicine.

  3. Low perceived social support predicts later depression but not social phobia in middle adolescence

    OpenAIRE

    Väänänen, Juha-Matti; Marttunen, Mauri; Helminen, Mika; Kaltiala-Heino, Riittakerttu

    2014-01-01

    Social phobia and depression are common and highly comorbid disorders in adolescence. There is a lack of studies on possible psychosocial shared risk factors for these disorders. The current study examined if low social support is a shared risk factor for both disorders among adolescent girls and boys. This study is a part of the Adolescent Mental Health Cohort Study's two-year follow-up. We studied cross-sectional and longitudinal associations of perceived social support with social phobia, ...

  4. Factors Predicting the Physical Activity Behavior of Female Adolescents: A Test of the Health Promotion Model

    OpenAIRE

    Mohamadian, Hashem; Ghannaee Arani, Mohammad

    2014-01-01

    Objectives Physical activity behavior begins to decline during adolescence and continues to decrease throughout young adulthood. This study aims to explain factors that influence physical activity behavior in a sample of female adolescents using a health promotion model framework. Methods This cross-sectional survey was used to explore physical activity behavior among a sample of female adolescents. Participants completed measures of physical activity, perceived self-efficacy, self-esteem, so...

  5. Peer Substance Use and Homelessness Predicting Substance Abuse from Adolescence Through Early Adulthood

    OpenAIRE

    Tompsett, Carolyn J.; Domoff, Sarah E.; Toro, Paul A.

    2013-01-01

    Adolescents who experience homelessness are at higher risk for abusing substances, and for being exposed to substance-using peers. The current study used a longitudinal design to track substance abuse, affiliation with substance-using peers, and episodes of homelessness among a sample of 223 adolescents who were homeless at thebaseline data collection and 148 adolescents who were housed at baseline. Participants were interviewed at six waves over 6.5 years, covering an age rang...

  6. Validity of Bioelectrical Impedance Measurement in Predicting Fat-Free Mass of Chinese Children and Adolescents

    OpenAIRE

    Wang, Lin; Hui, Stanley Sai-chuen; Wong, Stephen Heung-sang

    2014-01-01

    Background The current study aimed to examine the validity of various published bioelectrical impedance analysis (BIA) equations in estimating FFM among Chinese children and adolescents and to develop BIA equations for the estimation of fat-free mass (FFM) appropriate for Chinese children and adolescents. Material/Methods A total of 255 healthy Chinese children and adolescents aged 9 to 19 years old (127 males and 128 females) from Tianjin, China, participated in the BIA measurement at 50 kHz...

  7. Poor self-control and harsh punishment in childhood prospectively predict borderline personality symptoms in adolescent girls.

    Science.gov (United States)

    Hallquist, Michael N; Hipwell, Alison E; Stepp, Stephanie D

    2015-08-01

    Developmental theories of borderline personality disorder (BPD) propose that harsh, invalidating parenting of a child with poor self-control and heightened negative emotionality often leads to a coercive cycle of parent-child transactions that increase risk for BPD symptoms such as emotion dysregulation. Although parenting practices and child temperament have previously been linked with BPD, less is known about the prospective influences of caregiver and child characteristics. Using annual longitudinal data from the Pittsburgh Girls Study (n = 2,450), our study examined how reciprocal influences among harsh parenting, self-control, and negative emotionality between ages 5 and 14 predicted the development of BPD symptoms in adolescent girls ages 14 to 17. Consistent with developmental theories, we found that harsh punishment, poor self-control, and negative emotionality predicted BPD symptom severity at age 14. Only worsening self-control between ages 12 and 14, however, predicted growth in BPD symptoms from 14 to 17. Furthermore, the effects of harsh punishment and poor self-control on age 14 BPD symptoms were partially mediated by their earlier reciprocal effects on each other between ages 5 and 14. Our findings underscore the need to address both child and parental contributions to dysfunctional transactions in order to stem the development of BPD symptoms. Moreover, problems with self-regulation in early adolescence may indicate heightened risk for subsequent BPD. Altogether, these results increase our understanding of developmental trajectories associated with BPD symptoms in adolescent girls. PMID:25961815

  8. Validity of Some Anthropometric Indicators in the Prediction of High Systolic Blood Pressure Among Indian Adolescents

    Directory of Open Access Journals (Sweden)

    Shobha Rao

    2008-01-01

    Full Text Available Background: In view of the increasing prevalence of obesity in children, it is necessary to investigate the relative performance of different indicators used for its assessment and health consequences.Objectives: To examine concordance between various indicators used for assessing obesity among adolescents and to examine their ability to predict risk of high systolic blood pressure.Design: Cross-sectional study, from two schools catering to affluent class.Subjects: Children in age 9–16 yr (n = 1146 boys and 1036 girls.Measurements: Body weight, height, skinfold thickness at triceps (TSFT and body fat percent by trained investigators and blood pressure measurement by a pediatrician using sphygmomanometer.Results: Prevalence of overweight was lowest with criterion of TSFT (11.7% in boys; 7.6% in girls and was highest using criterion of body fat percent (53.7% in boys and 28.4% in girls. Body mass index (BMI had high significant correlation with each of the indicator and with systolic blood pressure (SBP as well, in both sexes. All the indicators with conventional cut offs showed poor sensitivity for predicting high SBP. However, receiver operating characteristics (ROC cut-offs improved sensitivity considerably, but the values were much lower compared to conventional cut-offs.Conclusions: There is considerable disparity in the estimates of overweight children obtained by different indicators. Lower values of ROC cut-offs highlights the need for population specific customized classification systems for assessing obesity in view of the probable population differences in relative risks of non-communicable adult diseases.

  9. Cumulative Family Risk Predicts Increases in Adjustment Difficulties across Early Adolescence

    Science.gov (United States)

    Buehler, Cheryl; Gerard, Jean M.

    2013-01-01

    Family is an important socialization context for youth as they move through early adolescence. A significant feature of this complex socialization context is the accumulation of potential family risk factors that may compromise youth adjustment. This study examined cumulative family risk and adolescents' adjustment difficulties in 416 two-parent…

  10. Parental Behaviors during Family Interactions Predict Changes in Depression and Anxiety Symptoms during Adolescence

    Science.gov (United States)

    Schwartz, Orli S.; Dudgeon, Paul; Sheeber, Lisa B.; Yap, Marie B. H.; Simmons, Julian G.; Allen, Nicholas B.

    2012-01-01

    This study investigated the prospective, longitudinal relations between parental behaviors observed during parent-adolescent interactions, and the development of depression and anxiety symptoms in a community-based sample of 194 adolescents. Positive and negative parental behaviors were examined, with negative behaviors operationalized to…

  11. Attachment to Parents, Best Friend, and Romantic Partner: Predicting Different Pathways to Depression in Adolescence

    Science.gov (United States)

    Margolese, Stephanie K.; Markiewicz, Dorothy; Doyle, Anna Beth

    2005-01-01

    Research indicates that insecurely-attached adolescents are at risk for depression, but little is known about factors that may influence or explain this vulnerability. The present study focuses on close relationships during adolescence and their association with depression. Specifically, the objectives were to investigate (1) the role of working…

  12. Possible Insomnia Predicts Some Risky Behaviors among Adolescents when Controlling for Depressive Symptoms

    Science.gov (United States)

    Catrett, Christina D.; Gaultney, Jane F.

    2009-01-01

    This study investigated whether previously reported links between sleep and risk taking among adolescents (E. M. O'Brien & J. A. Mindell, 2005) are associated--concurrently, longitudinally, or both--with sleep or underlying depression. The present study analyzed data from a nationally representative sample of 4,353 adolescents in the United States…

  13. Predicting Educational Outcomes and Psychological Well-Being in Adolescents Using Time Attitude Profiles

    Science.gov (United States)

    Andretta, James R.; Worrell, Frank C.; Mello, Zena R.

    2014-01-01

    Using cluster analysis of Adolescent Time Attitude Scale (ATAS) scores in a sample of 300 adolescents ("M" age = 16 years; "SD" = 1.25; 60% male; 41% European American; 25.3% Asian American; 11% African American; 10.3% Latino), the authors identified five time attitude profiles based on positive and negative attitudes toward…

  14. Anticipating Their Future: Adolescent Values for the Future Predict Adult Behaviors

    Science.gov (United States)

    Finlay, Andrea K.; Wray-Lake, Laura; Warren, Michael; Maggs, Jennifer

    2015-01-01

    Adolescent future values--beliefs about what will matter to them in the future--may shape their adult behavior. Utilizing a national longitudinal British sample, this study examined whether adolescent future values in six domains (i.e., family responsibility, full-time job, personal responsibility, autonomy, civic responsibility, and hedonistic…

  15. Trajectories of Psychosocial Problems in Adolescents Predicted by Findings From Early Well-Child Assessments

    NARCIS (Netherlands)

    Jaspers, Merlijne; de Winter, Andrea F.; Huisman, Mark; Verhulst, Frank C.; Ormel, Johan; Stewart, Roy E.; Reijneveld, Sijmen A.

    2012-01-01

    Purpose: To describe trajectories of emotional and behavioral problems in adolescents and to identify early indicators of these trajectories using data from routine well-child assessments at ages 0-4 years. Methods: Data from three assessment waves of adolescents (n = 1,816) of the TRAILS were used

  16. Changes in Loneliness during Middle Childhood Predict Risk for Adolescent Suicidality Indirectly through Mental Health Problems

    Science.gov (United States)

    Jones, Angela C.; Schinka, Katherine C.; van Dulmen, Manfred H. M.; Bossarte, Robert M.; Swahn, Monica H.

    2011-01-01

    We investigated whether changes in loneliness during middle childhood as well as from middle childhood into adolescence were associated with adolescent self-harm behaviors and suicidal thoughts using a community sample of 889 participants. Multivariate logistic regressions indicate that the relationship between changes in loneliness and…

  17. Gender, Pubertal Development, and Peer Sexual Harassment Predict Objectified Body Consciousness in Early Adolescence

    Science.gov (United States)

    Lindberg, Sara M.; Grabe, Shelly; Hyde, Janet Shibley

    2007-01-01

    Objectified body consciousness (OBC)--the tendency to view one's body as an object for others to look at and evaluate--is theorized to emerge during sexual maturation as adolescents, particularly adolescent girls, experience sexual objectification. Although OBC generally is discussed in developmental terms, research so far has examined primarily…

  18. Longitudinal Prediction of Adolescent Nonsuicidal Self-Injury: Examination of a Cognitive Vulnerability-Stress Model

    NARCIS (Netherlands)

    Guerry, J.D.; Prinstein, M.J.

    2010-01-01

    Virtually no longitudinal research has examined psychological characteristics or events that may lead to adolescent nonsuicidal self-injury (NSSI). This study tested a cognitive vulnerability-stress model as a predictor of NSSI trajectories. Clinically-referred adolescents (n = 143; 72% girls) compl

  19. Frontostriatal Maturation Predicts Cognitive Control Failure to Appetitive Cues in Adolescents

    Science.gov (United States)

    Somerville, Leah H.; Hare, Todd; Casey, B. J.

    2011-01-01

    Adolescent risk-taking is a public health issue that increases the odds of poor lifetime outcomes. One factor thought to influence adolescents' propensity for risk-taking is an enhanced sensitivity to appetitive cues, relative to an immature capacity to exert sufficient cognitive control. We tested this hypothesis by characterizing interactions…

  20. Prediction of Postpartum Social Support and Symptoms of Depression in Pregnant Adolescents: A Pilot Study

    Science.gov (United States)

    Logsdon, M. Cynthia; Cross, Rene; Williams, Beverly; Simpson, Theresa

    2004-01-01

    Many pregnant adolescents remain in school, creating unique challenges for professionals to meet their educational and health needs. In this descriptive pilot study of pregnant adolescents (n = 26), 68% demonstrated symptoms of depression as measured by the Center for Epidemiologic Studies Depression Scale (CES-D). In addition, there was an…

  1. A cross-sectional survey of complementary and alternative medicine use by children and adolescents attending the University Hospital of Wales

    Directory of Open Access Journals (Sweden)

    Lim Alissa

    2006-05-01

    Full Text Available Abstract Background A high prevalence of CAM use has been documented worldwide in children and adolescents with chronic illnesses. Only a small number of studies, however, have been conducted in the United Kingdom. The primary aim of this study was to examine the use of CAM by children and adolescents with a wide spectrum of acute and chronic medical problems in a tertiary children's hospital in Wales. Methods Structured personal interviews of 100 inpatients and 400 outpatients were conducted over a 2-month period in 2004. The yearly and monthly prevalence of CAM use were assessed and divided into medicinal and non-medicinal therapies. This use was correlated with socio-demographic factors. Results There were 580 patients approached to attain 500 completed questionnaires. The use of at least one type of CAM in the past year was 41% (95% CI 37–46% and past month 26% (95% CI 23–30%. The yearly prevalence of medicinal CAM was 38% and non-medicinal 12%. The users were more likely to have parents that were tertiary educated (mother: OR = 2.3, 95%CI 1.6–3.3 and a higher family income (Pearson chi-square for trend = 14.3, p None of the inpatient medical records documented CAM use in the past month. Fifty-two percent of medicinal and 38% of non-medicinal CAM users felt their doctor did not need to know about CAM use. Sixty-six percent of CAM users did not disclose the fact to their doctor. Three percent of all participants were using herbs and prescription medicines concurrently. Conclusion There is a high prevalence of CAM use in our study population. Paediatricians need to ensure that they ask parents and older children about their CAM usage and advise caution with regard to potential interactions. CAM is a rapidly expanding industry that requires further evidence-based research to provide more information on the effectiveness and safety of many CAM therapies. Statutory or self-regulation of the different segments of the industry is important

  2. Clinical Frailty Scale in an Acute Medicine Unit: a Simple Tool That Predicts Length of Stay

    Science.gov (United States)

    Juma, Salina; Taabazuing, Mary-Margaret; Montero-Odasso, Manuel

    2016-01-01

    Background Frailty is characterized by increased vulnerability to external stressors. When frail older adults are admitted to hospital, they are at increased risk of adverse events including falls, delirium, and disability. The Clinical Frailty Scale (CFS) is a practical and efficient tool for assessing frailty; however, its ability to predict outcomes has not been well studied within the acute medical service. Objective To examine the CFS in elderly patients admitted to the acute medical ward and its association with length of stay. Design Prospective cohort study in an acute care university hospital in London, Ontario, Canada, involving 75 patients over age 65, admitted to the general internal medicine clinical teaching units (CTU). Measurements Patient demographics were collected through chart review, and CFS score was assigned to each patient after brief clinician assessment. The CFS ranges from 1 (very fit) to 9 (terminally ill) based on descriptors and pictographs of activity and functional status. The CFS was collapsed into three categories: non-frail (CFS 1–4), mild-to-moderately frail (CFS 5–6), and severely frail (CFS 7–8). Outcomes of length of stay and 90-day readmission were gathered through the LHSC electronic patient record. Results Severe frailty was associated with longer lengths of stay (Mean = 12.6 ± 12.7 days) compared to mild-to-moderate frailty (mean = 11.2 ± 10.8 days), and non-frailty (mean = 4.1 ± 2.1 days, p = .014). This finding was significant after adjusting for age, sex, and number of medications. Participants with higher frailty scores showed higher readmission rates when compared with those with no frailty (31.2% for severely frail, vs. 34.2% for mild-to-moderately frail vs. 19% for non-frail) although there was no significant difference in the adjusted analysis. Conclusion The CFS helped identify patients that are more likely to have prolonged hospital stays on the acute medical ward. The CFS is an easy to use tool which

  3. Predicting airway hyperreactivity to mannitol using exhaled nitric oxide in an unselected sample of adolescents and young adults

    DEFF Research Database (Denmark)

    Sverrild, A; Malinovschi, A; Porsbjerg, C;

    2013-01-01

    the diagnostic accuracy of FeNO using absolute and normalized values to predict the presence of AHR to inhaled mannitol in an unselected population. Levels of FeNO and AHR to inhaled, dry-powder mannitol was measured in 180 unselected, steroid-naïve, non-smoking adolescents and young adults. The area under...... and specific tool for predicting the response to inhaled mannitol in an unselected sample of non-smoking, steroid-naïve subjects, and a low FeNO indicates that extra diagnostic work-up using inhaled mannitol will add very little extra information....

  4. The role of romantic attraction and conflict resolution in predicting shorter and longer relationship maintenance among adolescents.

    Science.gov (United States)

    Appel, Israel; Shulman, Shmuel

    2015-04-01

    This study examined the role of romantic attraction and conflict resolution patterns in shorter and longer relationship maintenance among adolescent couples. Data were used from 55 couples aged 15-18 years. Partners completed the Romantic Attraction scale and were observed negotiating a disagreement. Three and 6 months later, they were asked to report whether they were still together. Findings indicated that partners' romantic attraction and the tendency to minimize disagreements during interaction predicted shorter relationship maintenance. In contrast, longer relationship maintenance was predicted by partners' capability to resolve conflicts constructively in a positive atmosphere. Findings are embedded and discussed within Fisher's (2004) evolutionary theory of love.

  5. Application of social cognitive theory in predicting childhood obesity prevention behaviors in overweight and obese Iranian adolescents.

    Science.gov (United States)

    Bagherniya, Mohammad; Sharma, Manoj; Mostafavi, Firoozeh; Keshavarz, Seyed Ali

    2015-01-01

    The aim of this cross-sectional study was to use social cognitive theory to predict overweight and obesity behaviors in adolescent girls in Iran. Valid and reliable questionnaires about nutritional and physical activity regarding social cognitive theory constructs (self-efficacy, social support, outcome expectations, and outcome expectancies), dietary habits, and physical activity were filled by 172 overweight and obese girl adolescents. The mean age and body mass index were 13.4 ± 0.6 years and 28.2 ± 3.6 kg/m(2), respectively. Body mass index was significantly related to hours of television viewing (p = .003) and grams of junk food (p = .001). None of the social cognitive theory constructs were found to be significant predictors for servings of fruits and vegetables, grams of junk foods, minutes of physical activity, and hours of sedentary behaviors. In future, more culturally appropriate models need to be developed in Iran that can explain and predict prevention behaviors of obesity in Iranian adolescents.

  6. Predicting adolescents' disclosure of personal information in exchange for commercial incentives: an application of an extended theory of planned behavior.

    Science.gov (United States)

    Heirman, Wannes; Walrave, Michel; Ponnet, Koen

    2013-02-01

    This study adopts a global theoretical framework to predict adolescents' disclosure of personal information in exchange for incentives offered by commercial Websites. The study postulates and tests the validity of a model based on the theory of planned behavior (TPB), including antecedent factors of attitude and perceived behavioral control (PBC). A survey was conducted among 1,042 respondents. Results from SEM analyses show that the hypothesized model fits the empirical data well. The model accounts for 61.9 percent of the variance in adolescents' intention to disclose and 43.7 percent of the variance in self-reported disclosure. Perceived social pressure exerted by significant others (subjective norm) is the most important TPB factor in predicting intention to disclose personal information in exchange for incentives. This finding suggests that in discussions of adolescents' information privacy, the importance of social factors outweighs the individually oriented TPB factors of attitude and PBC. Moreover, privacy concern and trust propensity are significant predictors of respondents' attitudes toward online disclosure in exchange for commercial incentives, whereas the frequency of Internet use significantly affects their level of PBC. PMID:23113689

  7. A Latent Class Analysis of Maternal Responsiveness and Autonomy-Granting in Early Adolescence: Prediction to Later Adolescent Sexual Risk-Taking

    Science.gov (United States)

    Lanza, H. Isabella; Huang, David Y. C.; Murphy, Debra A.; Hser, Yih-Ing

    2013-01-01

    The present study sought to extend empirical inquiry related to the role of parenting on adolescent sexual risk-taking by using latent class analysis (LCA) to identify patterns of adolescent-reported mother responsiveness and autonomy-granting in early adolescence and examine associations with sexual risk-taking in mid- and late-adolescence.…

  8. Early Life Growth Predicts Pubertal Development in South African Adolescents123

    Science.gov (United States)

    Norris, Shane A; Martorell, Reynaldo; Mehta, Neil K; Richter, Linda M

    2016-01-01

    Background: Given global trends toward earlier onset of puberty and the adverse psychosocial consequences of early puberty, it is important to understand the childhood predictors of pubertal timing and tempo. Objective: We examined the association between early growth and the timing and tempo of puberty in adolescents in South Africa. Methods: We analyzed prospectively collected data from 1060 boys and 1135 girls participating in the Birth-to-Twenty cohort in Soweto, South Africa. Height-for-age z scores (HAZs) and body mass index–for-age z scores (BMIZs) were calculated based on height (centimeters) and body mass index (kilograms per meter squared) at ages 5 y and 8 y. The development of genitals, breasts, and pubic hair was recorded annually from 9 to 16 y of age with the use of the Tanner sexual maturation scale (SMS). We used latent class growth analysis to identify pubertal trajectory classes and also characterized children as fast or slow developers based on the SMS score at 12 y of age. We used multinomial logistic regression to estimate associations of HAZ and BMIZ at ages 5 and 8 y with pubertal development. Results: We identified 3 classes for pubic hair development (for both girls and boys) and 4 classes for breast (for girls) and genital (for boys) development. In girls, both HAZ and BMIZ at age 5 y were positively associated with pubic hair development [relative risk ratio (RRR): 1.57, P pubic hair development (RRR: 1.78, P < 0.001 and RRR: 1.43, P < 0.01, respectively); HAZ at age 5 y was associated with development of genitals (RRR: 2.19, P < 0.01). Conclusion: In boys and girls, both height and body mass index in early childhood predicted the trajectory of pubertal development. This may provide a tool to identify children at risk of early pubertal onset. PMID:26843589

  9. Adolescent self-organization predicts midlife memory in a prospective birth cohort study.

    Science.gov (United States)

    Xu, Man K; Jones, Peter B; Barnett, Jennifer H; Gaysina, Darya; Kuh, Diana; Croudace, Tim J; Richards, Marcus

    2013-12-01

    Childhood and adolescent mental health have a lasting impact on adult life chances, with strong implications for subsequent health, including cognitive aging. Using the British 1946 birth cohort, the authors tested associations between adolescent conduct problems, emotional problems and aspects of self-organization, and verbal memory at 43 years and rate of decline in verbal memory from 43 to 60-64 years. After controlling for childhood intelligence, adolescent self-organization was positively associated with verbal memory at 43 years, mainly through educational attainment, although not with rate of memory decline. Associations between adolescent conduct and emotional problems and future memory were of negligible magnitude. It has been suggested that interventions to improve self-organization may save a wide range of societal costs; this study also suggests that this might also benefit cognitive function in later life. PMID:24364401

  10. Frontostriatal maturation predicts cognitive control failure to appetitive cues in adolescents

    OpenAIRE

    Somerville, Leah H.; Hare, Todd A; Casey, B J

    2011-01-01

    Adolescent risk-taking is a public health issue that increases the odds of poor lifetime outcomes. One factor thought to influence adolescents' propensity for risk-taking is an enhanced sensitivity to appetitive cues, relative to an immature capacity to exert sufficient cognitive control. We tested this hypothesis by characterizing interactions among ventral striatal, dorsal striatal and prefrontal cortical regions with varying appetitive load using functional magnetic resonance imaging (fMRI...

  11. Utility of the theory of reasoned action and theory of planned behavior for predicting Chinese adolescent smoking.

    Science.gov (United States)

    Guo, Qian; Johnson, C Anderson; Unger, Jennifer B; Lee, Liming; Xie, Bin; Chou, Chih-Ping; Palmer, Paula H; Sun, Ping; Gallaher, Peggy; Pentz, MaryAnn

    2007-05-01

    One third of smokers worldwide live in China. Identifying predictors of smoking is important for prevention program development. This study explored whether the Theory of Reasoned Action (TRA) and Theory of Planned Behavior (TPB) predict adolescent smoking in China. Data were obtained from 14,434 middle and high school students (48.6% boys, 51.4% girls) in seven geographically varied cities in China. TRA and TPB were tested by multilevel mediation modeling, and compared by multilevel analyses and likelihood ratio tests. Perceived behavioral control was tested as a main effect in TPB and a moderation effect in TRA. The mediation effects of smoking intention were supported in both models (p<0.001). TPB accounted for significantly more variance than TRA (p<0.001). Perceived behavioral control significantly interacted with attitudes and social norms in TRA (p<0.001). Therefore, TRA and TPB are applicable to China to predict adolescent smoking. TPB is superior to TRA for the prediction and TRA can better predict smoking among students with lower than higher perceived behavioral control.

  12. Preschool externalizing behavior predicts gender-specific variation in adolescent neural structure.

    Directory of Open Access Journals (Sweden)

    Jessica Z K Caldwell

    Full Text Available Dysfunction in the prefrontal cortex, amygdala, and hippocampus is believed to underlie the development of much psychopathology. However, to date only limited longitudinal data relate early behavior with neural structure later in life. Our objective was to examine the relationship of early life externalizing behavior with adolescent brain structure. We report here the first longitudinal study linking externalizing behavior during preschool to brain structure during adolescence. We examined the relationship of preschool externalizing behavior with amygdala, hippocampus, and prefrontal cortex volumes at age 15 years in a community sample of 76 adolescents followed longitudinally since their mothers' pregnancy. A significant gender by externalizing behavior interaction revealed that males-but not females-with greater early childhood externalizing behavior had smaller amygdala volumes at adolescence (t = 2.33, p = .023. No significant results were found for the hippocampus or the prefrontal cortex. Greater early externalizing behavior also related to smaller volume of a cluster including the angular gyrus and tempoparietal junction across genders. Results were not attributable to the impact of preschool anxiety, preschool maternal stress, school-age internalizing or externalizing behaviors, or adolescent substance use. These findings demonstrate a novel, gender-specific relationship between early-childhood externalizing behavior and adolescent amygdala volume, as well as a cross-gender result for the angular gyrus and tempoparietal junction.

  13. Prediction of alcohol drinking in adolescents: Personality-traits, behavior, brain responses, and genetic variations in the context of reward sensitivity.

    Science.gov (United States)

    Heinrich, Angela; Müller, Kathrin U; Banaschewski, Tobias; Barker, Gareth J; Bokde, Arun L W; Bromberg, Uli; Büchel, Christian; Conrod, Patricia; Fauth-Bühler, Mira; Papadopoulos, Dimitri; Gallinat, Jürgen; Garavan, Hugh; Gowland, Penny; Heinz, Andreas; Ittermann, Bernd; Mann, Karl; Martinot, Jean-Luc; Paus, Tomáš; Pausova, Zdenka; Smolka, Michael; Ströhle, Andreas; Rietschel, Marcella; Flor, Herta; Schumann, Gunter; Nees, Frauke

    2016-07-01

    Adolescence is a time that can set the course of alcohol abuse later in life. Sensitivity to reward on multiple levels is a major factor in this development. We examined 736 adolescents from the IMAGEN longitudinal study for alcohol drinking during early (mean age=14.37) and again later (mean age=16.45) adolescence. Conducting structural equation modeling we evaluated the contribution of reward-related personality traits, behavior, brain responses and candidate genes. Personality seems to be most important in explaining alcohol drinking in early adolescence. However, genetic variations in ANKK1 (rs1800497) and HOMER1 (rs7713917) play an equal role in predicting alcohol drinking two years later and are most important in predicting the increase in alcohol consumption. We hypothesize that the initiation of alcohol use may be driven more strongly by personality while the transition to increased alcohol use is more genetically influenced. PMID:27180911

  14. Prediction of alcohol drinking in adolescents: Personality-traits, behavior, brain responses, and genetic variations in the context of reward sensitivity.

    Science.gov (United States)

    Heinrich, Angela; Müller, Kathrin U; Banaschewski, Tobias; Barker, Gareth J; Bokde, Arun L W; Bromberg, Uli; Büchel, Christian; Conrod, Patricia; Fauth-Bühler, Mira; Papadopoulos, Dimitri; Gallinat, Jürgen; Garavan, Hugh; Gowland, Penny; Heinz, Andreas; Ittermann, Bernd; Mann, Karl; Martinot, Jean-Luc; Paus, Tomáš; Pausova, Zdenka; Smolka, Michael; Ströhle, Andreas; Rietschel, Marcella; Flor, Herta; Schumann, Gunter; Nees, Frauke

    2016-07-01

    Adolescence is a time that can set the course of alcohol abuse later in life. Sensitivity to reward on multiple levels is a major factor in this development. We examined 736 adolescents from the IMAGEN longitudinal study for alcohol drinking during early (mean age=14.37) and again later (mean age=16.45) adolescence. Conducting structural equation modeling we evaluated the contribution of reward-related personality traits, behavior, brain responses and candidate genes. Personality seems to be most important in explaining alcohol drinking in early adolescence. However, genetic variations in ANKK1 (rs1800497) and HOMER1 (rs7713917) play an equal role in predicting alcohol drinking two years later and are most important in predicting the increase in alcohol consumption. We hypothesize that the initiation of alcohol use may be driven more strongly by personality while the transition to increased alcohol use is more genetically influenced.

  15. The Role of Attachment Style in Predicting Repetition of Adolescent Self-Harm: A Longitudinal Study.

    Science.gov (United States)

    Glazebrook, Katie; Townsend, Ellen; Sayal, Kapil

    2015-12-01

    This study investigated whether insecure attachment is associated with poorer outcomes at 6-month follow-up in adolescents who self-harm. At baseline the Child Attachment Interview was administered to 52 adolescents (13-17 years) referred to specialist child and adolescent mental health services and with a recent history of self-harm. Participants also completed self-report measures of self-harm, peer attachment, anxiety, and depression and were administered the means end problem-solving task. Self-harm behavior and problem-solving skills were assessed again at 6-month follow-up. At baseline, 14 (27%) were securely attached to their mothers. In the 49 (94%) adolescents followed-up, those with insecure maternal attachment and insecure peer attachment were more likely to have repeated self-harm. In addition, securely attached adolescents showed greater improvement in problem-solving skills. These findings indicate that secure maternal and peer attachments may help recovery from self-harm, possibly by supporting the acquisition of problem-solving skills, and highlights the importance of social connections and attachments for youth with a history of self-harm. PMID:25845416

  16. The Role of Attachment Style in Predicting Repetition of Adolescent Self-Harm: A Longitudinal Study.

    Science.gov (United States)

    Glazebrook, Katie; Townsend, Ellen; Sayal, Kapil

    2015-12-01

    This study investigated whether insecure attachment is associated with poorer outcomes at 6-month follow-up in adolescents who self-harm. At baseline the Child Attachment Interview was administered to 52 adolescents (13-17 years) referred to specialist child and adolescent mental health services and with a recent history of self-harm. Participants also completed self-report measures of self-harm, peer attachment, anxiety, and depression and were administered the means end problem-solving task. Self-harm behavior and problem-solving skills were assessed again at 6-month follow-up. At baseline, 14 (27%) were securely attached to their mothers. In the 49 (94%) adolescents followed-up, those with insecure maternal attachment and insecure peer attachment were more likely to have repeated self-harm. In addition, securely attached adolescents showed greater improvement in problem-solving skills. These findings indicate that secure maternal and peer attachments may help recovery from self-harm, possibly by supporting the acquisition of problem-solving skills, and highlights the importance of social connections and attachments for youth with a history of self-harm.

  17. Girls’ challenging social experiences in early adolescence predict neural response to rewards and depressive symptoms

    Directory of Open Access Journals (Sweden)

    Melynda D. Casement

    2014-04-01

    Full Text Available Developmental models of psychopathology posit that exposure to social stressors may confer risk for depression in adolescent girls by disrupting neural reward circuitry. The current study tested this hypothesis by examining the relationship between early adolescent social stressors and later neural reward processing and depressive symptoms. Participants were 120 girls from an ongoing longitudinal study of precursors to depression across adolescent development. Low parental warmth, peer victimization, and depressive symptoms were assessed when the girls were 11 and 12 years old, and participants completed a monetary reward guessing fMRI task and assessment of depressive symptoms at age 16. Results indicate that low parental warmth was associated with increased response to potential rewards in the medial prefrontal cortex (mPFC, striatum, and amygdala, whereas peer victimization was associated with decreased response to potential rewards in the mPFC. Furthermore, concurrent depressive symptoms were associated with increased reward anticipation response in mPFC and striatal regions that were also associated with early adolescent psychosocial stressors, with mPFC and striatal response mediating the association between social stressors and depressive symptoms. These findings are consistent with developmental models that emphasize the adverse impact of early psychosocial stressors on neural reward processing and risk for depression in adolescence.

  18. Social and economic antecedents and consequences of adolescent aggressive personality: Predictions from the interactionist model.

    Science.gov (United States)

    Conger, Rand D; Martin, Monica J; Masarik, April S; Widaman, Keith F; Donnellan, M Brent

    2015-11-01

    The present study examined the development of a cohort of 279 early adolescents (52% female) from 1990 to 2005. Guided by the interactionist model of socioeconomic status and human development, we proposed that parent aggressive personality, economic circumstances, interparental conflict, and parenting characteristics would affect the development of adolescent aggressive personality traits. In turn, we hypothesized that adolescent aggressiveness would have a negative influence on adolescent functioning as an adult in terms of economic success, personality development, and close relationships 11 years later. Findings were generally supportive of the interactionist model proposition that social and economic difficulties in the family of origin intensify risk for adolescent aggressive personality (the social causation hypothesis) and that this personality trait impairs successful transition to adult roles (the social selection hypothesis) in a transactional process over time and generations. These results underscore how early development leads to child influences that appear to directly hamper the successful transition to adult roles (statistical main effects) and also amplify the negative impact of dysfunctional family systems on the transition to adulthood (statistical interaction effects). The findings suggest several possible points of intervention that might help to disrupt this negative developmental sequence of events. PMID:26439065

  19. Cumulative family risk predicts increases in adjustment difficulties across early adolescence.

    Science.gov (United States)

    Buehler, Cheryl; Gerard, Jean M

    2013-06-01

    Family is an important socialization context for youth as they move through early adolescence. A significant feature of this complex socialization context is the accumulation of potential family risk factors that may compromise youth adjustment. This study examined cumulative family risk and adolescents' adjustment difficulties in 416 two-parent families using four waves of annual longitudinal data (51% female youth). Risk factors in four family domains were examined: socioeconomic, parents' psychological realm, marital, and parenting. Cumulative family risk experienced while in 6th grade was associated concurrently with daughters' higher internalizing problems and with increased internalizing problems during early adolescence. Cumulative family risk was associated concurrently with sons' higher externalizing problems and with daughters' increased externalizing problems over time. Cumulative family risk was associated concurrently with lower grades and with declining grades over time for both daughters and sons. The number of risk domains also was associated with youths' adjustment difficulties during early adolescence, providing evidence that risk in two-parent families involves more than ineffective parenting. These findings suggest a critical need to provide strong support for families in reducing a variety of stressors across multiple family domains as their children traverse early adolescence.

  20. Do online assessed self-report and behavioral measures of impulsivity-related constructs predict onset of substance use in adolescents?

    NARCIS (Netherlands)

    Janssen, Tim; Larsen, Helle; Peeters, Margot; Boendermaker, Wouter; Vollebergh, Wilma; Wiers, Reinout

    2015-01-01

    Abstract Introduction To prospectively predict the onset of use of alcohol, cigarettes and marijuana among Dutch adolescents, using behavioral and self-report measures of impulsivity-related facets. Specifically, we investigated whether behavioral measures of impulsivity predicted the onset of subst

  1. Do online assessed self-report and behavioral measures of impulsivity-related constructs predict onset of substance use in adolescents?

    NARCIS (Netherlands)

    T. Janssen; H. Larsen; M. Peeters; W.J. Boendermaker; W.A.M. Vollebergh; R.W. Wiers

    2015-01-01

    Introduction: To prospectively predict the onset of use of alcohol, cigarettes and marijuana among Dutch adolescents, using behavioral and self-report measures of impulsivity-related facets. Specifically, we investigated whether behavioral measures of impulsivity predicted the onset of substance use

  2. Prediction of post-treatment hypothyroidism using changes in thyroid volume after radioactive iodine therapy in adolescent patients with Graves' disease

    OpenAIRE

    Fukata Shuji; Nakatake Nobuhiro; Tajiri Junichi

    2011-01-01

    Abstract Background The goal of iodine-131 therapy for pediatric Graves' disease is to induce hypothyroidism. However, changes in post-treatment thyroid volume have not been investigated in pediatric and/or adolescent patients. Objective The aim of this retrospective study was to examine whether changes in thyroid volume predict post-treatment hypothyroidism in adolescent Graves' disease patients. Patients and Methods We used ultrasonography to examine changes in thyroid volume, and also asse...

  3. Fat-free mass prediction equations for bioelectric impedance analysis compared to dual energy X-ray absorptiometry in obese adolescents: a validation study

    OpenAIRE

    Hofsteenge, Geesje H.; Chinapaw, Mai JM; Weijs, Peter JM

    2015-01-01

    Background In clinical practice, patient friendly methods to assess body composition in obese adolescents are needed. Therefore, the bioelectrical impedance analysis (BIA) related fat-free mass (FFM) prediction equations (FFM-BIA) were evaluated in obese adolescents (age 11–18 years) compared to FFM measured by dual-energy x-ray absorptiometry (FFM-DXA) and a new population specific FFM-BIA equation is developed. Methods After an overnight fast, the subjects attended the outpatient clinic. Af...

  4. Parasympathetic nervous system activity predicts mood repair use and its effectiveness among adolescents with and without histories of major depression.

    Science.gov (United States)

    Yaroslavsky, Ilya; Rottenberg, Jonathan; Bylsma, Lauren M; Jennings, J Richard; George, Charles; Baji, Ildikó; Benák, István; Dochnal, Roberta; Halas, Kitti; Kapornai, Krisztina; Kiss, Enikő; Makai, Attila; Varga, Hedvig; Vetró, Ágnes; Kovacs, Maria

    2016-04-01

    Depressive disorders that onset in the juvenile years have been linked to far-reaching adverse consequences, making it imperative to elucidate key mechanisms and contributory factors. Excessive use of regulatory responses that exacerbate sadness (maladaptive mood repair) or insufficient use of regulatory responses that reduce it (adaptive mood repair) may reflect behavioral mechanisms of depression risk. Cardiac vagal control, indexed by patterns of respiratory sinus arrhythmia (RSA), has received attention as a putative physiological risk factor for depression. Although mood repair and RSA are related, the nature of this relationship is not well characterized in the context of depression risk. Therefore, we tested alternative models of the relationships between RSA patterns (at rest and in response to a sad film), trait mood repair, and the effectiveness of a mood repair response in the laboratory (state mood repair) among adolescents with depression histories (n = 210) and emotionally healthy peers (n = 161). In our data, a mediation model best explained the association between the key constructs: Adolescents with normative RSA patterns exhibited lower levels of depression and trait maladaptive mood repair, and benefited more from instructed (state) mood repair in the laboratory. By contrast, adolescents with atypical RSA patterns exhibited higher levels of depression and dispositional maladaptive mood repair, which, in turn, mediated the relations of RSA patterns and depression symptoms. Atypical RSA patterns also predicted reduced benefits from laboratory mood repair. PMID:26950752

  5. Sorting Test, Tower Test and BRIEF-SR do not predict school performance of healthy adolescents in preuniversity education

    Directory of Open Access Journals (Sweden)

    Annemarie eBoschloo

    2014-04-01

    Full Text Available Executive functions (EF such as self-monitoring, planning and organizing are known to develop through childhood and adolescence. They are of potential importance for learning and school performance. Earlier research into the relation between executive functions and school performance did not provide clear results possibly because confounding factors such as educational track, boy-girl differences and parental education were not taken into account. The present study therefore investigated the relation between executive function tests and school performance in a highly controlled sample of 173 healthy adolescents aged 12-18. Only students in the pre-university educational track were used and the performance of boys was compared to that of girls. Results showed that there was no relation between the report marks obtained and the performance on executive function tests, notably the Sorting Test and the Tower Test of the Delis-Kaplan Executive Functions System (D-KEFS. Likewise, no relation was found between the report marks and the scores on the Behavior Rating Inventory of Executive Function – Self-Report Version (BRIEF-SR after these were controlled for grade, sex, and level of parental education.The findings indicate that executive functioning as measured with widely used instruments such as the BRIEF-SR does not predict school performance of adolescents in preuniversity education any better than a student’s grade, sex, and level of parental education. ed

  6. Sorting Test, Tower Test, and BRIEF-SR do not predict school performance of healthy adolescents in preuniversity education.

    Science.gov (United States)

    Boschloo, Annemarie; Krabbendam, Lydia; Aben, Aukje; de Groot, Renate; Jolles, Jelle

    2014-01-01

    Executive functions (EF) such as self-monitoring, planning, and organizing are known to develop through childhood and adolescence. They are of potential importance for learning and school performance. Earlier research into the relation between EF and school performance did not provide clear results possibly because confounding factors such as educational track, boy-girl differences, and parental education were not taken into account. The present study therefore investigated the relation between executive function tests and school performance in a highly controlled sample of 173 healthy adolescents aged 12-18. Only students in the pre-university educational track were used and the performance of boys was compared to that of girls. Results showed that there was no relation between the report marks obtained and the performance on executive function tests, notably the Sorting Test and the Tower Test of the Delis-Kaplan Executive Functions System (D-KEFS). Likewise, no relation was found between the report marks and the scores on the Behavior Rating Inventory of Executive Function-Self-Report Version (BRIEF-SR) after these were controlled for grade, sex, and level of parental education. The findings indicate that executive functioning as measured with widely used instruments such as the BRIEF-SR does not predict school performance of adolescents in preuniversity education any better than a student's grade, sex, and level of parental education. PMID:24782794

  7. Does Sedentary Behavior Predict Academic Performance in Adolescents or the Other Way Round? A Longitudinal Path Analysis.

    Directory of Open Access Journals (Sweden)

    Jorge Lizandra

    Full Text Available This study examined whether adolescents' time spent on sedentary behaviors (academic, technological-based and social-based activities was a better predictor of academic performance than the reverse. A cohort of 755 adolescents participated in a three-year period study. Structural Equation Modeling techniques were used to test plausible causal hypotheses. Four competing models were analyzed to determine which model best fitted the data. The Best Model was separately tested by gender. The Best Model showed that academic performance was a better predictor of sedentary behaviors than the other way round. It also indicated that students who obtained excellent academic results were more likely to succeed academically three years later. Moreover, adolescents who spent more time in the three different types of sedentary behaviors were more likely to engage longer in those sedentary behaviors after the three-year period. The better the adolescents performed academically, the less time they devoted to social-based activities and more to academic activities. An inverse relationship emerged between time dedicated to technological-based activities and academic sedentary activities. A moderating auto-regressive effect by gender indicated that boys were more likely to spend more time on technological-based activities three years later than girls. To conclude, previous academic performance predicts better sedentary behaviors three years later than the reverse. The positive longitudinal auto-regressive effects on the four variables under study reinforce the 'success breeds success' hypothesis, with academic performance and social-based activities emerging as the strongest ones. Technological-based activities showed a moderating effect by gender and a negative longitudinal association with academic activities that supports a displacement hypothesis. Other longitudinal and covariate effects reflect the complex relationships among sedentary behaviors and academic

  8. Does Sedentary Behavior Predict Academic Performance in Adolescents or the Other Way Round? A Longitudinal Path Analysis.

    Science.gov (United States)

    Lizandra, Jorge; Devís-Devís, José; Pérez-Gimeno, Esther; Valencia-Peris, Alexandra; Peiró-Velert, Carmen

    2016-01-01

    This study examined whether adolescents' time spent on sedentary behaviors (academic, technological-based and social-based activities) was a better predictor of academic performance than the reverse. A cohort of 755 adolescents participated in a three-year period study. Structural Equation Modeling techniques were used to test plausible causal hypotheses. Four competing models were analyzed to determine which model best fitted the data. The Best Model was separately tested by gender. The Best Model showed that academic performance was a better predictor of sedentary behaviors than the other way round. It also indicated that students who obtained excellent academic results were more likely to succeed academically three years later. Moreover, adolescents who spent more time in the three different types of sedentary behaviors were more likely to engage longer in those sedentary behaviors after the three-year period. The better the adolescents performed academically, the less time they devoted to social-based activities and more to academic activities. An inverse relationship emerged between time dedicated to technological-based activities and academic sedentary activities. A moderating auto-regressive effect by gender indicated that boys were more likely to spend more time on technological-based activities three years later than girls. To conclude, previous academic performance predicts better sedentary behaviors three years later than the reverse. The positive longitudinal auto-regressive effects on the four variables under study reinforce the 'success breeds success' hypothesis, with academic performance and social-based activities emerging as the strongest ones. Technological-based activities showed a moderating effect by gender and a negative longitudinal association with academic activities that supports a displacement hypothesis. Other longitudinal and covariate effects reflect the complex relationships among sedentary behaviors and academic performance and the

  9. Does Sedentary Behavior Predict Academic Performance in Adolescents or the Other Way Round? A Longitudinal Path Analysis.

    Science.gov (United States)

    Lizandra, Jorge; Devís-Devís, José; Pérez-Gimeno, Esther; Valencia-Peris, Alexandra; Peiró-Velert, Carmen

    2016-01-01

    This study examined whether adolescents' time spent on sedentary behaviors (academic, technological-based and social-based activities) was a better predictor of academic performance than the reverse. A cohort of 755 adolescents participated in a three-year period study. Structural Equation Modeling techniques were used to test plausible causal hypotheses. Four competing models were analyzed to determine which model best fitted the data. The Best Model was separately tested by gender. The Best Model showed that academic performance was a better predictor of sedentary behaviors than the other way round. It also indicated that students who obtained excellent academic results were more likely to succeed academically three years later. Moreover, adolescents who spent more time in the three different types of sedentary behaviors were more likely to engage longer in those sedentary behaviors after the three-year period. The better the adolescents performed academically, the less time they devoted to social-based activities and more to academic activities. An inverse relationship emerged between time dedicated to technological-based activities and academic sedentary activities. A moderating auto-regressive effect by gender indicated that boys were more likely to spend more time on technological-based activities three years later than girls. To conclude, previous academic performance predicts better sedentary behaviors three years later than the reverse. The positive longitudinal auto-regressive effects on the four variables under study reinforce the 'success breeds success' hypothesis, with academic performance and social-based activities emerging as the strongest ones. Technological-based activities showed a moderating effect by gender and a negative longitudinal association with academic activities that supports a displacement hypothesis. Other longitudinal and covariate effects reflect the complex relationships among sedentary behaviors and academic performance and the

  10. Factors Predicting Behavioral Response to a Physical Activity Intervention among Adolescent Females

    Science.gov (United States)

    Dunton, Genevieve Fridlund; Schneider, Margaret; Cooper, Dan M.

    2007-01-01

    Objective: To determine whether individual factors influenced rates of physical activity change in response to a school-based intervention. Methods: Sedentary adolescent females (N = 63) participated in a 9-month physical activity program. Weekly levels of leisure-time physical activity were reported using an interactive website. Results: Change…

  11. Parental Warmth, Control, and Involvement in Schooling: Predicting Academic Achievement among Korean American Adolescents.

    Science.gov (United States)

    Kim, Kyoungho; Rohner, Ronald P.

    2002-01-01

    Explored the relationship between parenting style and academic achievement of Korean American adolescents, investigating the influence of perceived parental warmth and control and improvement in schooling. Survey data indicated that authoritative paternal parenting related to optimal academic achievement. Differences in maternal parenting styles…

  12. Subjective Invulnerability and Perceptions of Tobacco-Related Benefits Predict Adolescent Smoking Behavior

    Science.gov (United States)

    Morrell, Holly E. R.; Lapsley, Daniel K.; Halpern-Felsher, Bonnie L.

    2016-01-01

    Identifying factors that influence adolescents' decisions to start smoking is necessary to improve interventions for reducing tobacco use. The current longitudinal study was designed to determine the direction of influence between feelings of invulnerability to harm and cigarette smoking, and to test whether the perceived risks and benefits of…

  13. Learned Social Hopelessness: The Role of Explanatory Style in Predicting Social Support during Adolescence

    Science.gov (United States)

    Ciarrochi, Joseph; Heaven, Patrick C. L.

    2008-01-01

    Background: Almost no research has examined the impact of explanatory style on social adjustment. We hypothesised that adolescents with a pessimistic style would be less likely to develop and maintain social support networks. Methods: Seven hundred and nineteen students (351 males and 366 females; 2 unknown; M[subscript AGE] = 12.28, SD = 0.49)…

  14. How Do School Connectedness and Attachment to Parents Interrelate in Predicting Adolescent Depressive Symptoms?

    Science.gov (United States)

    Shochet, Ian M.; Homel, Ross; Cockshaw, Wendell D.; Montgomery, Danielle T.

    2008-01-01

    In this study, we tested whether school connectedness mediated or moderated the effect of parental attachment on adolescent depressive symptoms. A sample of 153 secondary school students ranging from 8th to 12th grade were assessed using measures of parental attachment, school connectedness, and depressive symptoms. Independently, parental…

  15. Peer victimization, deviant peer affiliation and impulsivity: Predicting adolescent problem behaviors.

    Science.gov (United States)

    Zhu, Jianjun; Yu, Chengfu; Zhang, Wei; Bao, Zhenzhou; Jiang, Yanping; Chen, Yuanyuan; Zhen, Shuangju

    2016-08-01

    Abundant evidence has demonstrated an association between peer victimization and adolescent problem behaviors. However, there is a large gap in knowledge about the potential mediators that associate peer victimization with problem behaviors and the potential moderators that exacerbate or buffer this association. The current study examined whether deviant peer affiliation mediated the association between peer victimization and problem behaviors and whether the direct and indirect associations were moderated by impulsivity. A sample of 1401 adolescents (50.1% boys, 11-14 years old) completed anonymous questionnaires regarding peer victimization, impulsivity, deviant peer affiliation, and problem behaviors. Gender, age and socioeconomic status (SES) were controlled for in the analyses. Structural equation models showed that peer victimization was significantly associated with more problem behaviors, and this association was mediated by deviant peer affiliation. Impulsivity moderated both the direct association (peer victimization→problem behaviors) and the second stage of the indirect path (deviant peer affiliation→problem behaviors). Specifically, these associations were especially stronger for adolescents with higher impulsivity. Identifying the processes by which peer victimization is associated with adolescent problem behaviors has important implications for an integrative framework of theory and prevention. PMID:27348798

  16. Testing Social Cognitive Theory as a Theoretical Framework to Predict Smoking Relapse among Daily Smoking Adolescents

    NARCIS (Netherlands)

    Zundert, R.M.P. van; Nijhof, L.M.; Engels, R.C.M.E.

    2009-01-01

    Predictors of adolescent smoking relapse are largely unknown, since studies either focus on relapse among adults, or address (long-term) smoking cessation but not relapse. In the present study, Social Cognitive Theory (SCT) was used as a theoretical framework to examine the first and second lapses,

  17. Emotional and Adrenocortical Regulation in Early Adolescence: Prediction by Attachment Security and Disorganization in Infancy

    Science.gov (United States)

    Spangler, Gottfried; Zimmermann, Peter

    2014-01-01

    The aim of the present study was to examine differences in emotion expression and emotion regulation in emotion-eliciting situations in early adolescence from a bio-psycho-social perspective, specifically investigating the influence of early mother-infant attachment and attachment disorganization on behavioural and adrenocortical responses. The…

  18. Do Guilt- and Shame-Proneness Differentially Predict Prosocial, Aggressive, and Withdrawn Behaviors during Early Adolescence?

    Science.gov (United States)

    Roos, Sanna; Hodges, Ernest V. E.; Salmivalli, Christina

    2014-01-01

    In this short-term longitudinal study, we systematically examined the distinctiveness of guilt- and shame-proneness in early adolescents (N = 395, mean age = 11.8 years) in terms of differential relations with peer reported prosocial behavior, withdrawal, and aggression. Results from structural equation modeling indicated that guilt-proneness…

  19. The Cost of Materialism in a Collectivistic Culture: Predicting Risky Behavior Engagement in Chinese Adolescents

    Science.gov (United States)

    Auerbach, Randy P.; McWhinnie, Chad M.; Goldfinger, Marc; Abela, John R. Z.; Zhu, Xiongzhao; Yao, Shuqiao

    2010-01-01

    The goals of the current study were to examine whether (a) negative events mediate the relationship between materialism and risky behavior engagement and (b) materialism moderates the relationship between stress and engagement in risky behaviors in Chinese youth. At Time 1, 406 adolescents (ages 14-19) from Yue Yang, China, completed measures…

  20. Emotional Support and Expectations from Parents, Teachers, and Peers Predict Adolescent Competence at School

    Science.gov (United States)

    Wentzel, Kathryn R.; Russell, Shannon; Baker, Sandra

    2016-01-01

    We examined perceived emotional support and expectations from parents, teachers, and classmates in relation to Mexican American adolescents' (n = 398) social behavior and academic functioning. Results of regression analyses indicated that direct associations between emotional support and expectations differ as a function of source and domain;…

  1. Internet Use and Video Gaming Predict Problem Behavior in Early Adolescence

    Science.gov (United States)

    Holtz, Peter; Appel, Markus

    2011-01-01

    In early adolescence, the time spent using the Internet and video games is higher than in any other present-day age group. Due to age-inappropriate web and gaming content, the impact of new media use on teenagers is a matter of public and scientific concern. Based on current theories on inappropriate media use, a study was conducted that comprised…

  2. Examining the Correlation between Perceived Social Support in Adolescence and Bullying in Terms of Prediction

    Science.gov (United States)

    Isiklar, Abdullah; Sar, Ali Haydar; Celik, Aslihan

    2012-01-01

    This research was carried out to examine perceived social support in adolescence and bullying. 112 females and 171 males (in total 283) attending different types of high schools were used in this research. The sample group includes students who were referred to guidance and counseling service as bullies. According to the research results; when…

  3. Frontostriatal maturation predicts cognitive control failure to appetitive cues in adolescents.

    Science.gov (United States)

    Somerville, Leah H; Hare, Todd; Casey, B J

    2011-09-01

    Adolescent risk-taking is a public health issue that increases the odds of poor lifetime outcomes. One factor thought to influence adolescents' propensity for risk-taking is an enhanced sensitivity to appetitive cues, relative to an immature capacity to exert sufficient cognitive control. We tested this hypothesis by characterizing interactions among ventral striatal, dorsal striatal, and prefrontal cortical regions with varying appetitive load using fMRI scanning. Child, teen, and adult participants performed a go/no-go task with appetitive (happy faces) and neutral cues (calm faces). Impulse control to neutral cues showed linear improvement with age, whereas teens showed a nonlinear reduction in impulse control to appetitive cues. This performance decrement in teens was paralleled by enhanced activity in the ventral striatum. Prefrontal cortical recruitment correlated with overall accuracy and showed a linear response with age for no-go versus go trials. Connectivity analyses identified a ventral frontostriatal circuit including the inferior frontal gyrus and dorsal striatum during no-go versus go trials. Examining recruitment developmentally showed that teens had greater between-subject ventral-dorsal striatal coactivation relative to children and adults for happy no-go versus go trials. These findings implicate exaggerated ventral striatal representation of appetitive cues in adolescents relative to an intermediary cognitive control response. Connectivity and coactivity data suggest these systems communicate at the level of the dorsal striatum differentially across development. Biased responding in this system is one possible mechanism underlying heightened risk-taking during adolescence. PMID:20809855

  4. Readiness to Recover in Adolescent Anorexia Nervosa: Prediction of Hospital Admission

    Science.gov (United States)

    Ametller, L.; Castro, J.; Serrano, E.; Martinez, E.; Toro, J.

    2005-01-01

    Objectives: To determine if motivation to change in anorexia nervosa during treatment is a predictor of hospitalisation in adolescent patients. Method: The Anorexia Nervosa Stages of Change Questionnaire (ANSOCQ), the Eating Disorders Inventory-2 (EDI-2) and the Beck Depression Inventory (BDI) were administered to a group of 70 anorexia nervosa…

  5. Neurocognitive processes and the prediction of addictive behaviors in late adolescence

    NARCIS (Netherlands)

    Ö. Korucuoğlu

    2015-01-01

    The primary aim of this dissertation was to investigate the effect of acute alcohol on neurocognitive systems involved in the development of addictive behaviours in adolescents. A secondary aim was to investigate whether alcohol-induced changes in cognitive and affective processes would be predictiv

  6. Parenting Practices, Parental Attachment and Aggressiveness in Adolescence: A Predictive Model

    Science.gov (United States)

    Gallarin, Miriam; Alonso-Arbiol, Itziar

    2012-01-01

    The aim of this study was twofold: a) to test the mediation role of attachment between parenting practices and aggressiveness, and b) to clarify the differential role of mothers and fathers with regard to aggressiveness. A total of 554 adolescents (330 girls and 224 boys), ages ranging between 16 and 19, completed measures of mothers' and fathers'…

  7. The 220-age equation does not predict maximum heart rate in children and adolescents

    NARCIS (Netherlands)

    Verschuren, Olaf; Maltais, Desiree B.; Takken, Tim

    2011-01-01

    Our primary purpose was to provide maximum heart rate (HR(max)) values for ambulatory children with cerebral palsy (CP). The secondary purpose was to determine the effects of age, sex, ambulatory ability, height, and weight on HR(max). In 362 ambulatory children and adolescents with CP (213 males an

  8. Internalizing symptoms and rumination: The prospective prediction of familial and peer emotional victimization experiences during adolescence

    OpenAIRE

    Shapero, Benjamin G.; Hamilton, Jessica L.; Liu, Richard T.; Abramson, Lyn Y.; Alloy, Lauren B.

    2013-01-01

    Adolescence is marked by increases in stressful life events. Although research has demonstrated that depressed individuals generate stress, few studies investigate the generation of emotional victimization. The current study examined the effects of rumination and internalizing symptoms on experiences of peer victimization and familial emotional abuse.

  9. Theory of mind and switching predict prospective memory performance in adolescents

    NARCIS (Netherlands)

    Altgassen, A.M.; Vetter, N.C.; Phillips, L.H.; Akgün, C.; Kliegel, M.

    2014-01-01

    Research indicates ongoing development of prospective memory as well as theory of mind and executive functions across late childhood and adolescence. However, so far the interplay of these processes has not been investigated. Therefore, the purpose of the current study was to investigate whether the

  10. Substance Use in Adolescence and Early Adulthood: Which Best Predicts Violence in Early Adulthood?

    Science.gov (United States)

    Marcus, Robert F.; Jamison, Eric G., II

    2013-01-01

    Waves I and III of the National Longitudinal Study of Adolescent Health (Add Health) were used to test the contributions of alcohol, tobacco, marijuana, cocaine, LSD, PCP, and other illicit drugs to violence in early adulthood (e.g., took part in a gang fight, pulled a knife or gun, used a weapon in a fight, used a weapon to get something). The…

  11. Cognitive impairment effects of early life stress in adolescents can be predicted with early biomarkers: Impacts of sex, experience, and cytokines.

    Science.gov (United States)

    Grassi-Oliveira, Rodrigo; Honeycutt, Jennifer A; Holland, Freedom H; Ganguly, Prabarna; Brenhouse, Heather C

    2016-09-01

    Childhood adversity increases vulnerability to psychiatric disorders that emerge in adolescence, in a sex-dependent manner. Early adversity modeled in rodents with maternal separation (MS) affects cognition and medial prefrontal cortex (mPFC) circuitry. Humans and animals exposed to early life adversity also display heightened circulating inflammatory cytokines, however the predictive relationship of these early measures with later behavioral deficits is unknown. Here, male and female rats were exposed to MS or control rearing during the postnatal period (P2-21). Blood samples were taken at distinct developmental time points for analysis of the pro-inflammatory cytokine IL-1β and the anti-inflammatory cytokines IL-4, and IL-10, followed by win-shift cognitive testing and analysis of mPFC parvalbumin (PVB) immunofluorescent interneurons in adolescence. Regression analyses were conducted to explore the relationship between early cytokines and adolescent behavioral measures. We observed sex- and age-dependent effects of MS on circulating cytokines. MS also yielded adolescent decreases in mPFC PVB and cognitive deficits, which were predicted by early cytokine expression in a sex- and experience-dependent manner. Taken together, the present data reveals that circulating cytokines and PVB levels are predictive of adolescent cognitive deficits, and therefore provide compelling evidence for a putative role of early biomarkers in mediating MS-induced behavioral dysfunction. Importantly, predictive relationships often depended on sex and on MS history, suggesting that early life experiences may yield individualistic mechanisms of vulnerability compared to the general population. PMID:27235636

  12. Cognitive impairment effects of early life stress in adolescents can be predicted with early biomarkers: Impacts of sex, experience, and cytokines.

    Science.gov (United States)

    Grassi-Oliveira, Rodrigo; Honeycutt, Jennifer A; Holland, Freedom H; Ganguly, Prabarna; Brenhouse, Heather C

    2016-09-01

    Childhood adversity increases vulnerability to psychiatric disorders that emerge in adolescence, in a sex-dependent manner. Early adversity modeled in rodents with maternal separation (MS) affects cognition and medial prefrontal cortex (mPFC) circuitry. Humans and animals exposed to early life adversity also display heightened circulating inflammatory cytokines, however the predictive relationship of these early measures with later behavioral deficits is unknown. Here, male and female rats were exposed to MS or control rearing during the postnatal period (P2-21). Blood samples were taken at distinct developmental time points for analysis of the pro-inflammatory cytokine IL-1β and the anti-inflammatory cytokines IL-4, and IL-10, followed by win-shift cognitive testing and analysis of mPFC parvalbumin (PVB) immunofluorescent interneurons in adolescence. Regression analyses were conducted to explore the relationship between early cytokines and adolescent behavioral measures. We observed sex- and age-dependent effects of MS on circulating cytokines. MS also yielded adolescent decreases in mPFC PVB and cognitive deficits, which were predicted by early cytokine expression in a sex- and experience-dependent manner. Taken together, the present data reveals that circulating cytokines and PVB levels are predictive of adolescent cognitive deficits, and therefore provide compelling evidence for a putative role of early biomarkers in mediating MS-induced behavioral dysfunction. Importantly, predictive relationships often depended on sex and on MS history, suggesting that early life experiences may yield individualistic mechanisms of vulnerability compared to the general population.

  13. A Latent Class Analysis of Maternal Responsiveness and Autonomy-Granting in Early Adolescence: Prediction to Later Adolescent Sexual Risk-Taking

    OpenAIRE

    Lanza, H. Isabella; David Y C Huang; Murphy, Debra A.; Hser, Yih-Ing

    2013-01-01

    The present study sought to extend empirical inquiry related to the role of parenting on adolescent sexual risk-taking by using latent class analysis (LCA) to identify patterns of adolescent-reported mother responsiveness and autonomy-granting in early adolescence and examine associations with sexual risk-taking in mid- and late-adolescence. Utilizing a sample of 12- to 14-year-old adolescents (N = 4,743) from the 1997 National Longitudinal Survey of Youth (NLSY97), results identified a four-...

  14. Nursing, Pharmacy, or Medicine? Disgust Sensitivity Predicts Career Interest among Trainee Health Professionals

    Science.gov (United States)

    Consedine, Nathan S.; Yu, Tzu-Chieh; Windsor, John A.

    2013-01-01

    Given global demand on health workforces, understanding student enrollment motivations are critical. Prior studies have concentrated on variation in career and lifestyle values; the current work evaluated the importance of disgust sensitivity in the prediction of health career interests. We argue that emotional proclivities may be important and…

  15. COMPUTING THERAPY FOR PRECISION MEDICINE: COLLABORATIVE FILTERING INTEGRATES AND PREDICTS MULTI-ENTITY INTERACTIONS

    OpenAIRE

    Regenbogen, Sam; WILKINS, ANGELA D.; Lichtarge, Olivier

    2016-01-01

    Biomedicine produces copious information it cannot fully exploit. Specifically, there is considerable need to integrate knowledge from disparate studies to discover connections across domains. Here, we used a Collaborative Filtering approach, inspired by online recommendation algorithms, in which non-negative matrix factorization (NMF) predicts interactions among chemicals, genes, and diseases only from pairwise information about their interactions. Our approach, applied to ...

  16. Predicting Unprotected Sex and Unplanned Pregnancy among Urban African-American Adolescent Girls Using the Theory of Gender and Power.

    Science.gov (United States)

    Rosenbaum, Janet E; Zenilman, Jonathan; Rose, Eve; Wingood, Gina; DiClemente, Ralph

    2016-06-01

    Reproductive coercion has been hypothesized as a cause of unprotected sex and unplanned pregnancies, but research has focused on a narrow set of potential sources of reproductive coercion. We identified and evaluated eight potential sources of reproductive coercion from the Theory of Gender and Power including economic inequality between adolescent girls and their boyfriends, cohabitation, and age differences. The sample comprised sexually active African-American female adolescents, ages 15-21. At baseline (n = 715), 6 months (n = 607), and 12 months (n = 605), participants completed a 40-min interview and were tested for semen Y-chromosome with polymerase chain reaction from a self-administered vaginal swab. We predicted unprotected sex and pregnancy using multivariate regression controlling for demographics, economic factors, relationship attributes, and intervention status using a Poisson working model. Factors associated with unprotected sex included cohabitation (incidence risk ratio (IRR) 1.48, 95 % confidence interval (1.22, 1.81)), physical abuse (IRR 1.55 (1.21, 2.00)), emotional abuse (IRR 1.31 (1.06, 1.63)), and having a boyfriend as a primary source of spending money (IRR 1.18 (1.00, 1.39)). Factors associated with unplanned pregnancy 6 months later included being at least 4 years younger than the boyfriend (IRR 1.68 (1.14, 2.49)) and cohabitation (2.19 (1.35, 3.56)). Among minors, cohabitation predicted even larger risks of unprotected sex (IRR 1.93 (1.23, 3.03)) and unplanned pregnancy (3.84 (1.47, 10.0)). Adolescent cohabitation is a marker for unprotected sex and unplanned pregnancy, especially among minors. Cohabitation may have stemmed from greater commitment, but the shortage of affordable housing in urban areas could induce women to stay in relationships for housing. Pregnancy prevention interventions should attempt to delay cohabitation until adulthood and help cohabiting adolescents to find affordable housing.

  17. Predicting Unprotected Sex and Unplanned Pregnancy among Urban African-American Adolescent Girls Using the Theory of Gender and Power.

    Science.gov (United States)

    Rosenbaum, Janet E; Zenilman, Jonathan; Rose, Eve; Wingood, Gina; DiClemente, Ralph

    2016-06-01

    Reproductive coercion has been hypothesized as a cause of unprotected sex and unplanned pregnancies, but research has focused on a narrow set of potential sources of reproductive coercion. We identified and evaluated eight potential sources of reproductive coercion from the Theory of Gender and Power including economic inequality between adolescent girls and their boyfriends, cohabitation, and age differences. The sample comprised sexually active African-American female adolescents, ages 15-21. At baseline (n = 715), 6 months (n = 607), and 12 months (n = 605), participants completed a 40-min interview and were tested for semen Y-chromosome with polymerase chain reaction from a self-administered vaginal swab. We predicted unprotected sex and pregnancy using multivariate regression controlling for demographics, economic factors, relationship attributes, and intervention status using a Poisson working model. Factors associated with unprotected sex included cohabitation (incidence risk ratio (IRR) 1.48, 95 % confidence interval (1.22, 1.81)), physical abuse (IRR 1.55 (1.21, 2.00)), emotional abuse (IRR 1.31 (1.06, 1.63)), and having a boyfriend as a primary source of spending money (IRR 1.18 (1.00, 1.39)). Factors associated with unplanned pregnancy 6 months later included being at least 4 years younger than the boyfriend (IRR 1.68 (1.14, 2.49)) and cohabitation (2.19 (1.35, 3.56)). Among minors, cohabitation predicted even larger risks of unprotected sex (IRR 1.93 (1.23, 3.03)) and unplanned pregnancy (3.84 (1.47, 10.0)). Adolescent cohabitation is a marker for unprotected sex and unplanned pregnancy, especially among minors. Cohabitation may have stemmed from greater commitment, but the shortage of affordable housing in urban areas could induce women to stay in relationships for housing. Pregnancy prevention interventions should attempt to delay cohabitation until adulthood and help cohabiting adolescents to find affordable housing. PMID:27188460

  18. Prediction of Early Recurrence of Liver Cancer by a Novel Discrete Bayes Decision Rule for Personalized Medicine

    Science.gov (United States)

    Ogihara, Hiroyuki

    2016-01-01

    We discuss a novel diagnostic method for predicting the early recurrence of liver cancer with high accuracy for personalized medicine. The difficulty with cancer treatment is that even if the types of cancer are the same, the cancers vary depending on the patient. Thus, remarkable attention has been paid to personalized medicine. Unfortunately, although the Tokyo Score, the Modified JIS, and the TNM classification have been proposed as liver scoring systems, none of these scoring systems have met the needs of clinical practice. In this paper, we convert continuous and discrete data to categorical data and keep the natively categorical data as is. Then, we propose a discrete Bayes decision rule that can deal with the categorical data. This may lead to its use with various types of laboratory data. Experimental results show that the proposed method produced a sensitivity of 0.86 and a specificity of 0.49 for the test samples. This suggests that our method may be superior to the well-known Tokyo Score, the Modified JIS, and the TNM classification in terms of sensitivity. Additional comparative study shows that if the numbers of test samples in two classes are the same, this method works well in terms of the F1 measure compared to the existing scoring methods. PMID:27800494

  19. Predicting Positive Citizenship from Adolescence to Young Adulthood: The Effects of a Civic Context.

    Science.gov (United States)

    Zaff, Jonathan F; Malanchuk, Oksana; Eccles, Jacquelynne S

    2008-01-01

    Researchers have theorized that programs to promote positive citizenship should begin with an opportunity for adolescents to participate in civic activities, such as community service or political volunteering. In this article we extend the theory by arguing that a more systemic approach is needed, in which a civic context is developed to promote citizenship. We hypothesize that living within a consistent civic context leads to civic engagement in late adolescence and into young adulthood. We use a diverse, longitudinal dataset to test this hypothesis. We find that social interactions with peers, parent modeling of civic behaviors, and cultural factors, such as ethnicity-specific practices, cumulatively result in a higher level of civic activities among youth and that a continued context that includes these factors results in a higher level of civic activities into adulthood. The implications of our findings are discussed with regard to program and policy development. PMID:22837638

  20. Predicting Adolescent Anxiety: The Role of Acculturation, Negative Life Events, Ethnicity, Social Support, and Coping

    OpenAIRE

    Lewis, Krystal Monique

    2009-01-01

    Epidemiological studies indicate that between 8 and 20% of children suffer from an anxiety disorder (Costello, Egger, & Angold, 2004). Researchers have worked for many years to map the developmental trajectory of anxiety in children, yet the pathways remain unclear. The primary purpose of this study was to determine the relationship between specific predictors and anxiety in middle school Caucasian and African American adolescents. A secondary purpose was to explore whether acculturation cont...

  1. Early Life Growth Predicts Pubertal Development in South African Adolescents 1 2 3

    OpenAIRE

    Lundeen, Elizabeth A.; Norris, Shane A; Martorell, Reynaldo; Suchdev, Parminder S; Mehta, Neil K.; Richter, Linda M; Stein, Aryeh D.

    2016-01-01

    Background: Given global trends toward earlier onset of puberty and the adverse psychosocial consequences of early puberty, it is important to understand the childhood predictors of pubertal timing and tempo. Objective: We examined the association between early growth and the timing and tempo of puberty in adolescents in South Africa. Methods: We analyzed prospectively collected data from 1060 boys and 1135 girls participating in the Birth-to-Twenty cohort in Soweto, South Africa. Height-for-...

  2. Emotional Reactivity and Exposure to Household Stress in Childhood Predict Psychological Problems in Adolescence

    OpenAIRE

    Shapero, Benjamin G.; STEINBERG, LAURENCE

    2013-01-01

    In recent years, research has examined the role of heightened emotional reactivity and poor regulation on maladjustment during childhood and adolescence. Although much of this research has shown a direct link between high emotional reactivity and maladjustment, there is less research on the ways in which reactivity interacts with contextual factors. Using data from the NICHD Study of Early Child Care and Youth Development (SECCYD), the current study asks how emotional reactivity in childhood,...

  3. International Youth Justice Systems: Promoting Youth Development and Alternative Approaches: A Position Paper of the Society for Adolescent Health and Medicine.

    Science.gov (United States)

    2016-10-01

    Youth incarceration is an international public health concern among developed and developing countries. Worldwide, youth are held in incarceration, detention, and other secure settings that are inappropriate for their age and developmental stages, jeopardizing their prosocial development, and reintegration into society. Youth incarceration lacks evidence and cost-effectiveness. The well-being of youth is a key indicator of the welfare of families, communities, and society at large; therefore, the Society for Adolescent Health and Medicine (SAHM) supports a paradigm shift in the role of the justice system as it relates to treatment of youth. SAHM recommends justice systems focus greater attention and resources on identifying and reducing the antecedents of high-risk and criminal behaviors, recognizing the rights and freedom of young persons, and prioritizing the well-being of youth over punitive measures that may harm and disrupt healthy adolescent development. SAHM supports the following positions: (1) incarceration is a last option for selected offenders who have committed the most serious violent crimes and are unable to remain safely in the community; (2) youth justice policies, programs, and practices affecting youth be evidence based and trauma informed; (3) youth justice policies, programs, and practices must incorporate research and ongoing program evaluation; (4) youth justice policies shall protect the privacy and dignity of children younger than 18 years; and (5) health care professionals and media will promote positive portrayals of youth in healthy relationships within their communities and reduce representations and images of youth that are negative, violent, deviant, and threatening. PMID:27664466

  4. Is medicine use in adolescence risk behavior? Cross-sectional survey of school-aged children from 11 to 15

    DEFF Research Database (Denmark)

    Andersen, Anette; Holstein, Bjørn E; Hansen, Ebba Holme

    2006-01-01

    : A random sample of schools in Denmark in 2002. Participants: All students in the fifth, seventh and ninth grades in these schools, n = 4824. Measurements: Self-reported medicine use for headache, stomachache, difficulties in getting to sleep, and nervousness within the last month; self-reported experience...... that medicine use can be regarded as part of a cluster of risk behaviors among young people....

  5. Is chemical synthetic accessibility computationally predictable for drug and lead-like molecules? A comparative assessment between medicinal and computational chemists.

    Science.gov (United States)

    Bonnet, Pascal

    2012-08-01

    The design of lead and drug-like molecules with expected desired properties and feasible chemical synthesis is one of the main objectives of computational and medicinal chemists. Prediction of synthetic feasibility of de novo molecules is often achieved by the use of in-silico tools or by advices received from medicinal and to a lesser extent from computational chemists. However, the validation of predictive tools is often performed on selection of compounds from external databases. In this study, we compare the synthetic accessibility (SA) score predicted by SYLVIA and the score estimated by medicinal chemists who synthesized the molecules. Therefore, we solicited 11 bench-based medicinal and computational chemists to score 119 lead-like molecules synthesized by same medicinal chemists. Their scores were compared with score calculated from SYLVIA software. Irrespective of the starting material database, we obtained a good agreement between average of medicinal and computational chemist scores for the ensemble of compounds; as well as between all chemists and SYLVIA SA scores with a correlation of 0.7. Furthermore, analysis of the marketed drugs since 1970 shows some consistency in average SYLVIA SA scores. Compounds entered in different phases of clinical trials show some large variation in synthetic accessibility scores due to natural-derived molecular scaffolds. Here, we proposed that the selection of compounds based on synthetically accessibility should not be done solely by one individual chemist to avoid personal gut-feeling appreciation from its experience but by a group of medicinal and computational chemists. By assessing synthetic accessibility of hundreds of compounds synthesized by medicinal chemists, we show that SYLVIA can be used efficiently to rank and prioritize virtual compound libraries in drug discovery processes.

  6. Personalized medicine in psoriasis: developing a genomic classifier to predict histological response to Alefacept

    Directory of Open Access Journals (Sweden)

    Haider Asifa S

    2010-02-01

    Full Text Available Abstract Background Alefacept treatment is highly effective in a select group patients with moderate-to-severe psoriasis, and is an ideal candidate to develop systems to predict who will respond to therapy. A clinical trial of 22 patients with moderate to severe psoriasis treated with alefacept was conducted in 2002-2003, as a mechanism of action study. Patients were classified as responders or non-responders to alefacept based on histological criteria. Results of the original mechanism of action study have been published. Peripheral blood was collected at the start of this clinical trial, and a prior analysis demonstrated that gene expression in PBMCs differed between responders and non-responders, however, the analysis performed could not be used to predict response. Methods Microarray data from PBMCs of 16 of these patients was analyzed to generate a treatment response classifier. We used a discriminant analysis method that performs sample classification from gene expression data, via "nearest shrunken centroid method". Centroids are the average gene expression for each gene in each class divided by the within-class standard deviation for that gene. Results A disease response classifier using 23 genes was created to accurately predict response to alefacept (12.3% error rate. While the genes in this classifier should be considered as a group, some of the individual genes are of great interest, for example, cAMP response element modulator (CREM, v-MAF avian musculoaponeurotic fibrosarcoma oncogene family (MAFF, chloride intracellular channel protein 1 (CLIC1, also called NCC27, NLR family, pyrin domain-containing 1 (NLRP1, and CCL5 (chemokine, cc motif, ligand 5, also called regulated upon activation, normally T expressed, and presumably secreted/RANTES. Conclusions Although this study is small, and based on analysis of existing microarray data, we demonstrate that a treatment response classifier for alefacept can be created using gene

  7. Predicting antisocial behavior among latino young adolescents: an ecological systems analysis.

    Science.gov (United States)

    Eamon, Mary Keegan; Mulder, Cray

    2005-01-01

    The authors used data from a national sample of 420 Latino young adolescents to examine multiple predictors of antisocial behavior within an ecological systems framework. They found that boys and youths who lived a higher proportion of their life in poverty exhibited higher levels of antisocial behavior, and mothers' acculturation was associated with lower levels. Neighborhood and school environments, exposure to deviant peer pressure, and 3 parenting practices--parent-youth attachment, physical punishment, and mothers' monitoring--were related to Latino youth antisocial behavior. Neighborhood quality and peer pressure explained the relation between poverty and an increased risk for antisocial behavior.

  8. Initiating Moderate to Heavy Alcohol Use Predicts Changes in Neuropsychological Functioning for Adolescent Girls and Boys

    OpenAIRE

    Squeglia, L M; Spadoni, A D; Infante, M. A.; Myers, M. G.; Tapert, S. F.

    2009-01-01

    This study prospectively examines the influence of alcohol on neuropsychological functioning in a sample of boys and girls who were characterized prior to initiating drinking (N=76, ages 12–14). Adolescents who transitioned into heavy (n= 25; 11 female, 14 male) or moderate (n=11; 2 female, 9 male) drinking were compared to demographically-matched controls who remained non-users throughout the approximately 3-year follow-up period (n=40; 16 female, 24 male). For girls, more drinking days in t...

  9. Influences of combined therapies with traditional Chinese medicine on pulmonary function and surface average electromyogram ratio in adolescent idiopathic scoliosis patients

    Directory of Open Access Journals (Sweden)

    Jia-ping SHEN

    2016-09-01

    Full Text Available Objective  To evaluate the influences of traditional Chinese medicinal combined therapies on pulmonary function and surface average electromyogram (AEMG ratio in adolescent idiopathic scoliosis patients. Methods  One hundred and twenty outpatients with mild and moderate adolescent idiopathic scoliosis were randomly divided into a Traditional Chinese Medicine (TCM group and a brace group. TCM group patients underwent i Navigation of the spinal balance (twice a day, 40min/ time, until to skeletal maturity; ii Balance manipulation (twice a week, 25min/time, lasted 12 months; iii Small needle-knife therapy (once a week, 10 times. The brace group patients were treated with a Milwaukee brace. The Cobb angle was measured after 12 and 24 months of treatment, pulmonary function was determined after 12 months of treatment, and AEMG ratio of the surface electromyogram was measured 6, 12, 18 and 24 months after treatment, and intergroup comparison was performed. Results  The Cobb angle significantly decreased in both groups 12 months after treatment (P0.05 in the TCM group and brace group, respectively, 12 months after treatment and 62.5% and 34.7% (P<0.05, respectively, 24 months aftertreatment. Pulmonary function was significantly improved 12 months after treatment in TCM group (P<0.05 but significantly decreased in brace group (P<0.05. The AEMG ratio was significantly reduced (P<0.01 and tended to remain at 1 after stopping treatment in TCM group, showed that the muscle imbalance existed on both sides of the scoliosis, but was adverse in brace group (P<0.05, showed that the muscle imbalance aggravated. No side effect of the therapeutic method was found. Conclusions  The spinal balance therapy based on traditional Chinese medicine theory has excellent therapeutic efficacy and safety, and can significantly ameliorate the imbalance existed on both sides of the scoliosis, improve lung function index, and have better compliance. The AEMG ratio is a

  10. Latino Adolescents' Ethnic Identity: Is There a Developmental Progression and Does Growth in Ethnic Identity Predict Growth in Self-Esteem?

    Science.gov (United States)

    Umana-Taylor, Adriana J.; Gonzales-Backen, Melinda A.; Guimond, Amy B.

    2009-01-01

    The current longitudinal study of 323 Latino adolescents (50.5% male; M age = 15.31 years) examined whether ethnic identity exploration, resolution, and affirmation demonstrated significant growth over a 4-year period and whether growth in ethnic identity predicted growth in self-esteem. Findings from multiple-group latent growth curve models…

  11. Irritable and Defiant Sub-Dimensions of ODD: Their Stability and Prediction of Internalizing Symptoms and Conduct Problems from Adolescence to Young Adulthood

    OpenAIRE

    Leadbeater, Bonnie J.; Homel, Jacqueline

    2015-01-01

    Emerging research has identified sub-dimensions of oppositional defiant disorder – irritability and defiance -that differentially predict internalizing and externalizing symptoms in preschoolers, children, and adolescents. Using a theoretical approach and confirmatory factor analyses to distinguish between irritability and defiance, we investigate the associations among these dimensions and internalizing (anxiety and depression) and externalizing problems (conduct problems) within and across ...

  12. Facial preferences in early adolescent girls: pubertal maturity predicts preferences maturity.

    Science.gov (United States)

    Kościński, Krzysztof

    2013-09-01

    Despite numerous studies on perception of facial attractiveness in adults, preferences in adolescents remain poorly recognized. The aim of present study was to explore facial preferences in girls at early adolescence (11-14 years old) and compare them with preferences of women. All females evaluated the same 30 male faces, which were also assessed by independent judges for several perceived features. Regardless of age, girls assessed attractiveness much the same as women, and the strengths of their preferences for specific facial features were similar to those of women. Except for the youngest girls, pubertal maturity (measured as the time elapsed since the menarche and breast development) correlated positively with the similarity of the girls' attractiveness evaluations to those of adult women and with strength of preference for cues to good biological quality (skin healthiness and sexy appearance). This remained true even after controlling for age and psychosexual development, suggesting thus that sex hormones are involved in development of facial preferences in pubescent girls. PMID:24308210

  13. Infant attachment predicts bodily freezing in adolescence: evidence from a prospective longitudinal study

    Directory of Open Access Journals (Sweden)

    Hannah C. M. Niermann

    2015-10-01

    Full Text Available Early life-stress, particularly maternal deprivation, is associated with long-lasting deviations in animals’ freezing responses. Given the relevance of freezing for stress-coping, translational research is needed to examine the relation between insecure infant-parent attachment and bodily freezing-like behavior in humans. Therefore, we investigated threat-related reductions in body sway (indicative of freezing-like behavior in 14-year-old adolescents (N=79, for whom attachment security was earlier assessed in infancy. As expected, insecure (versus secure attachment was associated with less body sway for angry versus neutral faces. This effect remained when controlling for intermediate life-events. These results suggest that the long-lasting effects of early negative caregiving experiences on the human stress and threat systems extend to the primary defensive reaction of freezing. Additionally, we replicated earlier work in adults, by observing a significant correlation (in adolescents assessed as securely attached between subjective state anxiety and reduced body sway in response to angry versus neutral faces. Together, this research opens venues to start exploring the role of freezing in the development of human psychopathology.

  14. Fear of Neighborhood Violence During Adolescence Predicts Development of Obesity a Decade Later: Gender Differences Among African Americans

    Science.gov (United States)

    Assari, Shervin; Moghani Lankarani, Maryam; Caldwell, Cleopatra Howard; Zimmerman, Marc A

    2016-01-01

    Background African American youth are more likely than other racial and ethnic groups to be obese. African American youth are also more likely to live in disadvantaged neighborhoods which increase their victimization, observation, and fear of violence. Objectives This study tested if victimization, observation, and fear of violence in the neighborhood during adolescence predict trajectory of body mass index (BMI) in the 3rd decade of life in African Americans. Patients and Methods Data came from an 18-year community-based cohort. We used multi-group latent growth curve modeling for data analysis, considering neighborhood violence at age 15 (i.e. victimization, observation, and fear) as predictors, and the linear slope for the average change in BMI from age 21 to 32 as the outcome, with age and socioeconomic status (i.e. intact family and parental employment) as covariates. Results Fear of neighborhood violence at age 15 was predictive of an increase in BMI from age 21 to 32 among female but not male African Americans. Victimization and observation of violence at age 15 did not predict BMI change from age 21 to 32 among female or male African Americans. Conclusions Fear of neighborhood violence is a contributing factor to increased risk of obesity for female African American youth who live in disadvantaged areas. This finding has implications for prevention of obesity among African American women who are at highest risk for obesity in the United States. Initiatives that enhance neighborhood safety are critical strategies for obesity prevention among African American women.

  15. Multivariate Models of Parent-Late Adolescent Gender Dyads: The Importance of Parenting Processes in Predicting Adjustment

    Science.gov (United States)

    McKinney, Cliff; Renk, Kimberly

    2008-01-01

    Although parent-adolescent interactions have been examined, relevant variables have not been integrated into a multivariate model. As a result, this study examined a multivariate model of parent-late adolescent gender dyads in an attempt to capture important predictors in late adolescents' important and unique transition to adulthood. The sample…

  16. Prediction of post-treatment hypothyroidism using changes in thyroid volume after radioactive iodine therapy in adolescent patients with Graves' disease

    Directory of Open Access Journals (Sweden)

    Fukata Shuji

    2011-11-01

    Full Text Available Abstract Background The goal of iodine-131 therapy for pediatric Graves' disease is to induce hypothyroidism. However, changes in post-treatment thyroid volume have not been investigated in pediatric and/or adolescent patients. Objective The aim of this retrospective study was to examine whether changes in thyroid volume predict post-treatment hypothyroidism in adolescent Graves' disease patients. Patients and Methods We used ultrasonography to examine changes in thyroid volume, and also assessed thyroid functions, at 0, 1, 3, 5, 8 and 12 months after iodine-131 treatment in 49 adolescents ranging in age from 12 to 19 years retrospectively. Based on thyroid function outcome at 12 months, patients were divided into two groups: 29 patients with overt hypothyroidism requiring levothyroxine replacement and 20 without overt hypothyroidism. We compared changes in post-radioiodine thyroid volume between the two groups. Results About 90% of patients whose thyroid volume at 3 months after iodine-131 administration was less than 50% of the original volume were hypothyroid by one year after treatment (positive predictive value 88%, sensitivity 75.9%, specificity 85.0%. Conclusions We believe ultrasonographic measurement of thyroid volume at 3 months after iodine-131 to be clinically useful for predicting post-treatment hypothyroidism in adolescent Graves' disease patients.

  17. Elasticity in portion selection is predicted by severity of anorexia and food type in adolescents.

    Science.gov (United States)

    Herzog, M; Douglas, C R; Kissileff, H R; Brunstrom, J M; Halmi, K A

    2016-08-01

    The size of portions that people select is an indicator of underlying mechanisms controlling food intake. Fears of eating excessive portions drive down the sizes of portions patients with anorexia nervosa (AN) can tolerate eating significantly below those of healthy controls (HC) (Kissileff et al., 2016). To determine whether patients with AN will also reduce the sizes of typical or ideal portions below those of controls, ANOVA was used to compare maximum tolerable, typical, and ideal portions of four foods (potatoes, rice, pizza, and M&M's) in the same group of 24 adolescent AN patients and 10 healthy adolescent controls (HC), on which only the maximal portion data were previously reported. Typical and ideal portion sizes did not differ on any food for AN, but for HC, typical portions sizes (kcals) became larger than ideal as the energy density of the food increased, and were significant for the most energy dense food. Ideal portions of low energy dense foods were the same for AN as for in HC. There was a significant 3-way (group × food × portion type) interaction, such that HC selected larger maximum than typical portions only for pizza. We therefore proposed that individuals of certain groups, depending on the food, can be flexible in the amounts of food chosen to be eaten. We call this difference between maximum-tolerable, and typical portion sizes selected "elasticity." Elasticity was significantly smaller for AN patients compared to HC for pizza and was significantly inversely correlated with severity of illness. This index could be useful for clinical assessment of AN patients, and those with eating problems such as in obesity and bulimia nervosa and tracking their response to treatment. PMID:27037222

  18. Prior adversities predict posttraumatic stress reactions in adolescents following the Oslo Terror events 2011

    Directory of Open Access Journals (Sweden)

    Dag Ø. Nordanger

    2014-05-01

    Full Text Available Background: Former studies suggest that prior exposure to adverse experiences such as violence or sexual abuse increases vulnerability to posttraumatic stress reactions in victims of subsequent trauma. However, little is known about how such a history affects responses to terror in the general adolescent population. Objective: To explore the role of prior exposure to adverse experiences as risk factors for posttraumatic stress reactions to the Oslo Terror events. Method: We used data from 10,220 high school students in a large cross-sectional survey of adolescents in Norway that took place seven months after the Oslo Terror events. Prior exposure assessed was: direct exposure to violence, witnessing of violence, and unwanted sexual acts. We explored how these prior adversities interact with well-established risk factors such as proximity to the events, perceived life threat during the terror events, and gender. Results: All types of prior exposure as well as the other risk factors were associated with terror-related posttraumatic stress reactions. The effects of prior adversities were, although small, independent of adolescents’ proximity to the terror events. Among prior adversities, only the effect of direct exposure to violence was moderated by perceived life threat. Exposure to prior adversities increased the risk of posttraumatic stress reactions equally for both genders, but proximity to the terror events and perceived life threat increased the risk more in females. Conclusions: Terror events can have a more destabilizing impact on victims of prior adversities, independent of their level of exposure. The findings may be relevant to mental health workers and others providing post-trauma health care.

  19. Traditional, complementary and alternative medical systems and their contribution to personalisation, prediction and prevention in medicine—person-centred medicine

    Directory of Open Access Journals (Sweden)

    Roberti di Sarsina Paolo

    2012-11-01

    Full Text Available Abstract Traditional, complementary and alternative medical (TCAM systems contribute to the foundation of person-centred medicine (PCM, an epistemological orientation for medical science which places the person as a physical, psychological and spiritual entity at the centre of health care and of the therapeutic process. PCM wishes to broaden the bio-molecular reductionistic approach of medical science towards an integration that allows people, doctors, nurses, health-care professionals and patients to become the real protagonists of the health-care scene. The doctor or caregiver needs to act out of empathy to meet the unique value of each human being, which unfolds over the course of a lifetime from conception to natural death. Knowledge of the human being should not be instrumental to economic or political interests, ideology, theories or religious dogma. Research needs to be broadened with methodological tools to investigate person-centred medical interventions. Salutogenesis is a fundamental principle of PCM, promoting health and preventing illness by strengthening the individual's self-healing abilities. TCAM systems also give tools to predict the insurgence of illness and treat it before the appearance of overt organic disease. A task of PCM is to educate people to take better care of their physical, psychological and spiritual health. Health-care education needs to be broadened to give doctors and health-care workers of the future the tools to act in innovative and highly differentiated ways, always guided by deep respect for individual autonomy, personal culture, religion and beliefs.

  20. Adolescent self-control predicts joint trajectories of marijuana use and depressive mood into young adulthood among urban African Americans and Puerto Ricans.

    Science.gov (United States)

    Pahl, Kerstin; Brook, Judith S; Lee, Jung Yeon

    2014-08-01

    Previous studies have identified an association between depressive mood and marijuana use. We examined adolescent self-control as a predictor of membership in joint developmental trajectories of depressive mood and marijuana use from adolescence to young adulthood. Urban African Americans and Puerto Ricans (N = 838) were sampled when participants were on average 14, 19, 24, and 29 years old. Using growth mixture modeling, four joint trajectory groups of depressive mood and marijuana use were established: low marijuana use/low depressive mood, low marijuana use/intermediate depressive mood, high marijuana use/low depressive mood, and high marijuana use/high depressive mood. Weighted logistic regression analysis showed that self-control at age 14 distinguished the high marijuana use/high depressive mood group and the low marijuana use/low depressive mood group from each of the other groups. Findings show that the co-occurrence of high levels of marijuana use and depressive mood from adolescence into young adulthood is predicted by low levels of self-control in adolescence. On the other hand, high selfcontrol is associated with low marijuana use and low levels of depression over time. Thus, while deficits in self-control in adolescence constitute a significant risk for maladjustment over time, high self-control exerts a protective factor with regard to marijuana use and depressive mood into young adulthood.

  1. Utilization of Western and Traditional Korean Medicine for Children and Adolescents with Mental Disorders: a Nationwide Population-based Study from 2010 to 2012.

    Science.gov (United States)

    Kim, Su Jin; Kim, Bongseog; Lee, Young Sik; Bahn, Geon Ho

    2016-05-01

    When in need of medical treatment, Korean citizens have a choice of practitioners of western medicine (WM) or Traditional Korean Medicine (TKM). However, the two branches frequently conflict with one another, particularly with regard to mental disorders. This study was designed to compare the utilization of WM and TKM, focusing on child/adolescent patients with mental disorders. We analyzed F-code (Mental and behavioral disorders) claims from the Korean Health Insurance Review and Assessment Service, including data from 0-18-year-old patients from 2010 to 2012. Slightly more men than women utilized WM, while TKM use was almost evenly balanced. WM claims increased with advancing age, whereas utilization of TKM was common for the 0-6 age group. In WM and TKM, the total number of claims relying on the National Health Insurance Service (NHIS) was 331,154 (92.78%) and 73,282 (97.85%), respectively, and the number of claims relying on medical aid was 25,753 (7.22%) and 1,610 (2.15%), respectively. The most frequent F-coded claim in WM was F90 (Hyperkinetic disorders), with 64,088 claims (17.96%), and that in TKM was F45 (Somatoform disorders), with 28,852 claims (38.52%). The prevalence of a single disorder without comorbidities was 168,764 (47.29%) in WM and 52,615 (70.25%) in TKM. From these data, we conclude that WM takes prevalence over TKM in cases of attention deficit/hyperactivity disorder (ADHD), as well as in psychological problems such as depression and anxiety. On the other hand, patients utilizing TKM more commonly present with physical health problems including somatoform problems, sleep, and eating disorders. PMID:27134500

  2. Prediction of cannabis and cocaine use in adolescence using decision trees and logistic regression

    Directory of Open Access Journals (Sweden)

    Alfonso L. Palmer

    2010-01-01

    Full Text Available Spain is one of the European countries with the highest prevalence of cannabis and cocaine use among young people. The aim of this study was to investigate the factors related to the consumption of cocaine and cannabis among adolescents. A questionnaire was administered to 9,284 students between 14 and 18 years of age in Palma de Mallorca (47.1% boys and 52.9% girls whose mean age was 15.59 years. Logistic regression and decision trees were carried out in order to model the consumption of cannabis and cocaine. The results show the use of legal substances and committing fraudulence or theft are the main variables that raise the odds of consuming cannabis. In boys, cannabis consumption and a family history of drug use increase the odds of consuming cocaine, whereas in girls the use of alcohol, behaviours of fraudulence or theft and difficulty in some personal skills influence their odds of consuming cocaine. Finally, ease of access to the substance greatly raises the odds of consuming cocaine and cannabis in both genders. Decision trees highlight the role of consuming other substances and committing fraudulence or theft. The results of this study gain importance when it comes to putting into practice effective prevention programmes.

  3. Sex Differences in Self-Report and Behavioral Measures of Disinhibition Predicting Marijuana Use Across Adolescence

    Science.gov (United States)

    Felton, Julia W.; Collado, Anahi; Shadur, Julia M.; Lejuez, Carl W.; MacPherson, Laura

    2015-01-01

    Disinhibition has been consistently linked to substance use across development. Recent research suggests, however, that these relations may be influenced by both sex and measurement approach. The current study examined the moderating effect of sex on the association between behavioral and self-report measures of disinhibition and marijuana use across adolescence. Participants were 115 boys and 89 girls initially evaluated at grade 8 using a laboratory behavioral assessment and self-report questionnaires of disinhibitory variables. Marijuana use was measured annually from grades 9 through 12. Results suggest that boys and girls did not differ on either self-reported or behaviorally assessed levels of disinhibition, and that disinhibition measured using both approaches was associated with increases in marijuana use over time. There was a significant interaction between sex and disinhibition, suggesting that boys (but not girls) who self-reported elevations in disinhibition evidenced greater increases in marijuana use. The current findings add to a growing literature supporting the importance of using multiple methods to assess disinhibition and highlight the critical role of biological sex in understanding these relations. PMID:26237324

  4. Network medicine

    DEFF Research Database (Denmark)

    Pawson, Tony; Linding, Rune

    2008-01-01

    for new therapeutic intervention. We argue that by targeting the architecture of aberrant signaling networks associated with cancer and other diseases new therapeutic strategies can be implemented. Transforming medicine into a network driven endeavour will require quantitative measurements of cell...... signaling processes; we will describe how this may be performed and combined with new algorithms to predict the trajectories taken by a cellular system either in time or through disease states. We term this approach, network medicine....

  5. Predictive Validity of the Columbia-Suicide Severity Rating Scale for Short-Term Suicidal Behavior: A Danish Study of Adolescents at a High Risk of Suicide

    DEFF Research Database (Denmark)

    Conway, Paul Maurice; Erlangsen, Annette; Teasdale, Thomas William;

    2016-01-01

    Objectives: Using the Columbia-Suicide Severity Rating Scale (C-SSRS), we examined the predictive and incremental predictive validity of past-month suicidal behavior and ideation for short-term suicidal behavior among adolescents at a high risk of suicide. Methods: The study was conducted in 2014...... behavior predicted subsequent suicidal behavior (actual attempts and suicidal behavior of any type, including preparatory acts, aborted, interrupted and actual attempts; mean follow-up of 80.8 days, SD = 52.4). Furthermore, we examined whether suicidal ideation severity and intensity incrementally...... predicted suicidal behavior at follow-up over and above suicidal behavior at baseline. Results: Actual suicide attempts at baseline strongly predicted suicide attempts at follow-up. Baseline suicidal ideation severity and intensity did not significantly predict future actual attempts over and above baseline...

  6. Predictive Validity of the Columbia-Suicide Severity Rating Scale for Short-Term Suicidal Behavior: A Danish Study of Adolescents at a High Risk of Suicide

    DEFF Research Database (Denmark)

    Conway, Paul Maurice; Erlangsen, Annette; Teasdale, Thomas William;

    2016-01-01

    Objectives: Using the Columbia-Suicide Severity Rating Scale (C-SSRS), we examined the predictive and incremental predictive validity of past-month suicidal behavior and ideation for 2 short-term suicidal behavior among adolescents at a high risk of suicide. Methods: The study was conducted in 2014...... behavior predicted subsequent suicidal behavior (actual attempts and suicidal behavior of any type, including preparatory acts, aborted, interrupted and actual attempts; mean follow-up of 80.8 days, SD = 52.4). Furthermore, we examined whether suicidal ideation severity and intensity incrementally...... predicted suicidal behavior at follow-up over and above suicidal behavior at baseline. Results: Actual suicide attempts at baseline strongly predicted suicide attempts at follow-up. Baseline suicidal ideation severity and intensity did not significantly predict future actual attempts over and above baseline...

  7. Early Adolescent Depressive Symptoms: Prediction from Clique Isolation, Loneliness, and Perceived Social Acceptance

    Science.gov (United States)

    Witvliet, Miranda; Brendgen, Mara; van Lier, Pol A. C.; Koot, Hans M.; Vitaro, Frank

    2010-01-01

    This study examined whether clique isolation predicted an increase in depressive symptoms and whether this association was mediated by loneliness and perceived social acceptance in 310 children followed from age 11-14 years. Clique isolation was identified through social network analysis, whereas depressive symptoms, loneliness, and perceived…

  8. Predicting having condoms available among adolescents: The role of personal norm and enjoyment

    NARCIS (Netherlands)

    Jellema, I.J.; Abraham, C.; Schaalma, H.P.; Gebhardt, W.A.; Empelen, P. van

    2013-01-01

    Objectives Having condoms available has been shown to be an important predictor of condom use. We examined whether or not personal norm and goal enjoyment contribute to predicting having condoms available in the context of cognition specified by the theory of planned behaviour (TPB). Design Prospect

  9. Ink and Holes: Correlates and Predictive Associations of Body Modification among Adolescents

    Science.gov (United States)

    Dukes, Richard L.; Stein, Judith A.

    2011-01-01

    We examined correlates and predictive associations of tattoos and body piercings among 1,462 Colorado students in grades 9 to 12. More boys (19%) than girls (17%) reported tattoos, but more girls (42%) than boys (16%) reported piercings (earlobes not included). Older students reported more body modification. Structural equation models showed that…

  10. Adolescent sexuality in the limelight. Study and predictability of condom use through the theory of planned behaviour

    OpenAIRE

    Eufrosini Barmpagianni; Sofia Zyga

    2011-01-01

    Adolescents' sexual behavior is the focus of attention since increased levels of unintended pregnancy, abortions and sexually transmitted diseases are detected. Psychological, family and social factors contribute to the above mentioned situations. The aim of the present research was to examine the intention of condom use in adolescents of both sexes using the Theory of Planned Behavior. Material- Method: The study population consisted of 378 adolescents, aged 15 to 18. Data was collected by t...

  11. Tracking blood glucose and predicting prediabetes in Chinese children and adolescents: a prospective twin study.

    Directory of Open Access Journals (Sweden)

    Guoying Wang

    Full Text Available We examined the tracking of blood glucose, the development of prediabetes, and estimated their genetic contributions in a prospective, healthy, rural Chinese twin cohort. This report includes 1,766 subjects (998 males, 768 females aged 6-21 years at baseline who completed a 6-year follow-up study. Oral glucose tolerance test was performed for all subjects at both baseline and follow-up. We found that subjects with low fasting plasma glucose (FPG or 2 h post-load glucose (PG levels at baseline tended to remain at the low level at follow-up. Subjects in the top tertile of baseline plasma glucose tended to have a higher risk of developing prediabetes at follow-up compared to the low tertile: in males, 37.6% vs. 27.6% for FPG and 37.2% vs. 25.7% for 2hPG, respectively; in females, 31.0% vs. 15.4% for FPG and 28.9% vs. 15.1% for 2 h PG, respectively. Genetic factors explained 43% and 41% of the variance of FPG, and 72% and 47% for impaired fasting glucose for males and females, respectively; environmental factors substantially contribute to 2hPG status and impaired glucose tolerance. In conclusion, in this cohort of healthy rural Chinese children and adolescents, we demonstrated that both FPG and 2hPG tracked well and was a strong predictor of prediabetes. The high proportion of children with top tertile of blood glucose progressed to prediabetes, and the incidence of prediabetes has a male predominance. Genetic factors play more important role in fasting than postload status, most of which was explained by unique environmental factors.

  12. Is the 90th Percentile Adequate? The Optimal Waist Circumference Cutoff Points for Predicting Cardiovascular Risks in 124,643 15-Year-Old Taiwanese Adolescents.

    Directory of Open Access Journals (Sweden)

    Jason Jiunshiou Lee

    Full Text Available Adolescent obesity has increased to alarming proportions globally. However, few studies have investigated the optimal waist circumference (WC of Asian adolescents. This study sought to establish the optimal WC cutoff points that identify a cluster of cardiovascular risk factors (CVRFs among 15-year-old ethnically Chinese adolescents. This study was a regional population-based study on the CVRFs among adolescents who enrolled in all the senior high schools in Taipei City, Taiwan, between 2011 and 2014. Four cross-sectional health examinations of first-year senior high school (grade 10 students were conducted from September to December of each year. A total of 124,643 adolescents aged 15 (boys: 63,654; girls: 60,989 were recruited. Participants who had at least three of five CVRFs were classified as the high-risk group. We used receiver-operating characteristic curves and the area under the curve (AUC to determine the optimal WC cutoff points and the accuracy of WC in predicting high cardiovascular risk. WC was a good predictor for high cardiovascular risk for both boys (AUC: 0.845, 95% confidence interval [CI]: 0.833-0.857 and girls (AUC: 0.763, 95% CI: 0.731-0.795. The optimal WC cutoff points were ≥78.9 cm for boys (77th percentile and ≥70.7 cm for girls (77th percentile. Adolescents with normal weight and an abnormal WC were more likely to be in the high cardiovascular risk group (odds ratio: 3.70, 95% CI: 2.65-5.17 compared to their peers with normal weight and normal WC. The optimal WC cutoff point of 15-year-old Taiwanese adolescents for identifying CVRFs should be the 77th percentile; the 90th percentile of the WC might be inadequate. The high WC criteria can help health professionals identify higher proportion of the adolescents with cardiovascular risks and refer them for further evaluations and interventions. Adolescents' height, weight and WC should be measured as a standard practice in routine health checkups.

  13. Empathy and nonattachment independently predict peer nominations of prosocial behavior of adolescents

    Science.gov (United States)

    Sahdra, Baljinder K.; Ciarrochi, Joseph; Parker, Philip D.; Marshall, Sarah; Heaven, Patrick

    2015-01-01

    There is a plethora of research showing that empathy promotes prosocial behavior among young people. We examined a relatively new construct in the mindfulness literature, nonattachment, defined as a flexible way of relating to one's experiences without clinging to or suppressing them. We tested whether nonattachment could predict prosociality above and beyond empathy. Nonattachment implies high cognitive flexibility and sufficient mental resources to step out of excessive self-cherishing to be there for others in need. Multilevel Poisson models using a sample of 15-year olds (N = 1831) showed that empathy and nonattachment independently predicted prosocial behaviors of helpfulness and kindness, as judged by same-sex and opposite-sex peers, except for when boys nominated girls. The effects of nonattachment remained substantial in more conservative models including self-esteem and peer nominations of liking. PMID:25852590

  14. Empathy and nonattachment independently predict peer nominations of prosocial behaviour of adolescents

    Directory of Open Access Journals (Sweden)

    Baljinder K Sahdra

    2015-03-01

    Full Text Available There is a plethora of research showing that empathy promotes prosocial behaviour among young people. We examined a relatively new construct in the mindfulness literature, nonattachment, defined as a flexible way of relating to one’s experiences without clinging to or suppressing them. We tested whether nonattachment could predict prosociality above and beyond empathy. Nonattachment implies high cognitive flexibility and sufficient mental resources to step out of excessive self-cherishing to be there for others in need. Multilevel Poisson models using a sample of 15-year olds (N=1831 showed that empathy and nonattachment independently predicted prosocial behaviours of helpfulness and kindness, as judged by same-sex and opposite-sex peers, except for when boys nominated girls. The effects of nonattachment remained substantial in more conservative models including self-esteem and peer nominations of liking.

  15. ADOLESCENTS' INTERNET ADDICTION IS PREDICTED BY PEER PRESSURE AND PERCEIVED SOCIAL SUPPORT

    OpenAIRE

    ESEN, Binnaz Kıran

    2009-01-01

    In this research the prediction internet addiction obtained by peer pressure and perceived social support is examined. This study is executed in 2006- 2007 academic year on 479 high school students who are between ages 15- 17. The data were collected with "Internet Addiction Scale", "Peer Pressure Scale" and "Perceived Social Support Scale". Data are tested by regression analysis. The results of research shows the facts that internet addic...

  16. Lower Psychological Well-Being and Excessive Sexual Interest Predict Symptoms of Compulsive Use of Sexually Explicit Internet Material Among Adolescent Boys

    OpenAIRE

    Doornwaard, Suzan M.; Regina J J M van den Eijnden; Baams, Laura; Vanwesenbeeck, Ine; ter Bogt, Tom F.M.

    2015-01-01

    Although a growing body of literature addresses the effects of young people’s use of sexually explicit Internet material, research on the compulsive use of this type of online content among adolescents and its associated factors is largely lacking. This study investigated whether factors from three distinct psychosocial domains (i.e., psychological well-being, sexual interests/behaviors, and impulsive-psychopathic personality) predicted symptoms of compulsive use of sexually explicit Internet...

  17. Predicting Internet risks: a longitudinal panel study of gratifications-sought, Internet addiction symptoms, and social media use among children and adolescents

    OpenAIRE

    Leung, Louis

    2014-01-01

    This study used longitudinal panel survey data collected from 417 adolescents at 2 points in time 1 year apart. It examined relationships between Internet risks changes in Time 2 and social media gratifications-sought, Internet addiction symptoms, and social media use all measured at Time 1. By controlling for age, gender, education, and criterion variable scores in Internet addiction at Time 1, entertainment and instant messaging use at Time 1 significantly predicted increased Internet addic...

  18. Does Feedback-Related Brain Response during Reinforcement Learning Predict Socio-motivational (In-)dependence in Adolescence?

    Science.gov (United States)

    Raufelder, Diana; Boehme, Rebecca; Romund, Lydia; Golde, Sabrina; Lorenz, Robert C; Gleich, Tobias; Beck, Anne

    2016-01-01

    This multi-methodological study applied functional magnetic resonance imaging to investigate neural activation in a group of adolescent students (N = 88) during a probabilistic reinforcement learning task. We related patterns of emerging brain activity and individual learning rates to socio-motivational (in-)dependence manifested in four different motivation types (MTs): (1) peer-dependent MT, (2) teacher-dependent MT, (3) peer-and-teacher-dependent MT, (4) peer-and-teacher-independent MT. A multinomial regression analysis revealed that the individual learning rate predicts students' membership to the independent MT, or the peer-and-teacher-dependent MT. Additionally, the striatum, a brain region associated with behavioral adaptation and flexibility, showed increased learning-related activation in students with motivational independence. Moreover, the prefrontal cortex, which is involved in behavioral control, was more active in students of the peer-and-teacher-dependent MT. Overall, this study offers new insights into the interplay of motivation and learning with (1) a focus on inter-individual differences in the role of peers and teachers as source of students' individual motivation and (2) its potential neurobiological basis. PMID:27199873

  19. Does feedback-related brain response during reinforcement learning predict socio-motivational (in-dependence in adolescence?

    Directory of Open Access Journals (Sweden)

    Diana eRaufelder

    2016-05-01

    Full Text Available This multi-methodological study applied functional magnetic resonance imaging (fMRI to investigate neural activation in a group of adolescent students (N = 88 during a probabilistic reinforcement learning task. We related patterns of emerging brain activity and individual learning rates to socio-motivational (in-dependence manifested in four different motivation types (MT: (1 peer-dependent MT, (2 teacher-dependent MT, (3 peer-and-teacher-dependent MT, (4 peer-and-teacher-independent MT. A multinomial regression analysis revealed that the individual learning rate predicts students’ membership to the independent MT, or the peer-and-teacher-dependent MT. Additionally, the striatum, a brain region associated with behavioral adaptation and flexibility, showed increased learning-related activation in students with motivational independence. Moreover, the prefrontal cortex, which is involved in behavioral control, was more active in students of the peer-and-teacher-dependent MT. Overall, this study offers new insights into the interplay of motivation and learning with (1 a focus on inter-individual differences in the role of peers and teachers as source of students’ individual motivation and (2 its potential neurobiological basis.

  20. Gonadal function, fertility, and reproductive medicine in childhood and adolescent cancer patients: a national survey of Japanese pediatric endocrinologists.

    Science.gov (United States)

    Miyoshi, Yoko; Yorifuji, Tohru; Horikawa, Reiko; Takahashi, Ikuko; Nagasaki, Keisuke; Ishiguro, Hiroyuki; Fujiwara, Ikuma; Ito, Junko; Oba, Mari; Kawamoto, Hiroshi; Fujisaki, Hiroyuki; Kato, Masashi; Shimizu, Chikako; Kato, Tomoyasu; Matsumoto, Kimikazu; Sago, Haruhiko; Takimoto, Tetsuya; Okada, Hiroshi; Suzuki, Nao; Yokoya, Susumu; Ogata, Tsutomu; Ozono, Keiichi

    2016-04-01

    An increasing number of pediatric cancer patients survive, and treatment-related infertility represents one of the most important issues for these patients. While official guidelines in Japan recommend long-term follow-up of childhood cancer survivors (CCSs), their gonadal function and fertility have not been clarified. To address this issue, we organized a working panel to compile evidence from long-term survivors who received treatments for cancer during childhood or adolescence. In collaboration with members of the CCS Committee of the Japanese Society for Pediatric Endocrinology (JSPE), we conducted a questionnaire survey regarding reproductive function in pediatric cancer patients. A cross-sectional survey was sent to 178 JSPE-certified councilors who were asked to self-evaluate the medical examinations they had performed. A total of 151 responses were obtained, revealing that 143 endocrinologists were involved in the care of CCSs. A quarter of the respondents reported having experienced issues during gonadal or reproductive examinations. Several survivors did not remember or fully understand the explanation regarding gonadal damage, and faced physical and psychological distress when discussing the risk of becoming infertile. Pediatric endocrinologists had anxieties regarding their patients' infertility and the risk of miscarriage, premature birth, and delivery problems. Only a limited number of endocrinologists had experience with managing childbirth and fertility preservation. Many councilors mentioned the necessity for inter-disciplinary communication among healthcare providers. Both endocrinologists and oncologists should set and follow a uniform clinical guideline that includes management of fertility of CCSs.

  1. Gonadal function, fertility, and reproductive medicine in childhood and adolescent cancer patients: a national survey of Japanese pediatric endocrinologists.

    Science.gov (United States)

    Miyoshi, Yoko; Yorifuji, Tohru; Horikawa, Reiko; Takahashi, Ikuko; Nagasaki, Keisuke; Ishiguro, Hiroyuki; Fujiwara, Ikuma; Ito, Junko; Oba, Mari; Kawamoto, Hiroshi; Fujisaki, Hiroyuki; Kato, Masashi; Shimizu, Chikako; Kato, Tomoyasu; Matsumoto, Kimikazu; Sago, Haruhiko; Takimoto, Tetsuya; Okada, Hiroshi; Suzuki, Nao; Yokoya, Susumu; Ogata, Tsutomu; Ozono, Keiichi

    2016-04-01

    An increasing number of pediatric cancer patients survive, and treatment-related infertility represents one of the most important issues for these patients. While official guidelines in Japan recommend long-term follow-up of childhood cancer survivors (CCSs), their gonadal function and fertility have not been clarified. To address this issue, we organized a working panel to compile evidence from long-term survivors who received treatments for cancer during childhood or adolescence. In collaboration with members of the CCS Committee of the Japanese Society for Pediatric Endocrinology (JSPE), we conducted a questionnaire survey regarding reproductive function in pediatric cancer patients. A cross-sectional survey was sent to 178 JSPE-certified councilors who were asked to self-evaluate the medical examinations they had performed. A total of 151 responses were obtained, revealing that 143 endocrinologists were involved in the care of CCSs. A quarter of the respondents reported having experienced issues during gonadal or reproductive examinations. Several survivors did not remember or fully understand the explanation regarding gonadal damage, and faced physical and psychological distress when discussing the risk of becoming infertile. Pediatric endocrinologists had anxieties regarding their patients' infertility and the risk of miscarriage, premature birth, and delivery problems. Only a limited number of endocrinologists had experience with managing childbirth and fertility preservation. Many councilors mentioned the necessity for inter-disciplinary communication among healthcare providers. Both endocrinologists and oncologists should set and follow a uniform clinical guideline that includes management of fertility of CCSs. PMID:27212796

  2. Gonadal function, fertility, and reproductive medicine in childhood and adolescent cancer patients: a national survey of Japanese pediatric endocrinologists

    Science.gov (United States)

    Miyoshi, Yoko; Yorifuji, Tohru; Horikawa, Reiko; Takahashi, Ikuko; Nagasaki, Keisuke; Ishiguro, Hiroyuki; Fujiwara, Ikuma; Ito, Junko; Oba, Mari; Kawamoto, Hiroshi; Fujisaki, Hiroyuki; Kato, Masashi; Shimizu, Chikako; Kato, Tomoyasu; Matsumoto, Kimikazu; Sago, Haruhiko; Takimoto, Tetsuya; Okada, Hiroshi; Suzuki, Nao; Yokoya, Susumu; Ogata, Tsutomu; Ozono, Keiichi

    2016-01-01

    Abstract. An increasing number of pediatric cancer patients survive, and treatment-related infertility represents one of the most important issues for these patients. While official guidelines in Japan recommend long-term follow-up of childhood cancer survivors (CCSs), their gonadal function and fertility have not been clarified. To address this issue, we organized a working panel to compile evidence from long-term survivors who received treatments for cancer during childhood or adolescence. In collaboration with members of the CCS Committee of the Japanese Society for Pediatric Endocrinology (JSPE), we conducted a questionnaire survey regarding reproductive function in pediatric cancer patients. A cross-sectional survey was sent to 178 JSPE-certified councilors who were asked to self-evaluate the medical examinations they had performed. A total of 151 responses were obtained, revealing that 143 endocrinologists were involved in the care of CCSs. A quarter of the respondents reported having experienced issues during gonadal or reproductive examinations. Several survivors did not remember or fully understand the explanation regarding gonadal damage, and faced physical and psychological distress when discussing the risk of becoming infertile. Pediatric endocrinologists had anxieties regarding their patients’ infertility and the risk of miscarriage, premature birth, and delivery problems. Only a limited number of endocrinologists had experience with managing childbirth and fertility preservation. Many councilors mentioned the necessity for inter-disciplinary communication among healthcare providers. Both endocrinologists and oncologists should set and follow a uniform clinical guideline that includes management of fertility of CCSs. PMID:27212796

  3. Expert opinion and controversies in sports and musculoskeletal medicine: the diagnosis and treatment of spondylolysis in adolescent athletes.

    Science.gov (United States)

    Standaert, Christopher J; Herring, Stanley A

    2007-04-01

    Although spondylolysis is relatively common in adolescent athletes, there are substantial disagreements in the literature concerning the best methods for diagnosing and treating the condition. Controversy particularly arises regarding the optimal use of available imaging modalities in the diagnosis of athletes with suspected pars defects and the extent of activity restriction or brace use required for appropriate treatment. Because there have been no controlled trials on the treatment of spondylolysis and only a very limited number of studies addressing potential imaging strategies, it is difficult to develop true evidence-based guidelines for this condition. Given the current state of the literature, it is our impression that nuclear imaging with single photon emission computed tomography followed by computed tomography, with a limited role for plain radiography, remains the standard for appropriately diagnosing a symptomatic pars lesion. Treatment hinges on activity restriction for an amount of time adequate to allow for symptom resolution and, when possible, potential bony healing followed by a progressive sport-specific rehabilitation program. The biomechanic effects of brace use in this population are not well understood, but there may be some detrimental effects to the use of a brace and there currently is no evidence that the routine use of a rigid brace results in any significant improvement in radiographic or functional outcome. PMID:17398258

  4. The Dopamine D2 Receptor Polymorphism (DRD2 TaqIA) Interacts with Maternal Parenting in Predicting Early Adolescent Depressive Symptoms: Evidence of Differential Susceptibility and Age Differences.

    Science.gov (United States)

    Zhang, Wenxin; Cao, Yanmiao; Wang, Meiping; Ji, Linqin; Chen, Liang; Deater-Deckard, Kirby

    2015-07-01

    Most gene-environment interaction research on depression has largely focused on negative environment and to a lesser extent on positive environment. Moreover, to date few studies have directly examined G × E at different periods in development, particularly during early adolescence. The present study addressed these issues by examining the concurrent and prospective longitudinal effects of maternal parenting, DRD2 TaqIA polymorphism, and their interaction on adolescent depressive symptoms in a sample of 1026 Chinese adolescents (Mage = 11.33 ± 0.47 years at T1, 50.3% girls) in a three-wave longitudinal study from age 11 to 13. Results indicated that maternal positive and negative parenting significantly concurrently predicted adolescent depressive symptoms at all three waves, whereas TaqIA polymorphism had no main effect on depressive symptoms. TaqIA polymorphism interacted with negative parenting in predicting concurrent depressive symptoms at age 11 and 12. A1 carriers were more susceptible to negative parenting compared to A2A2 homozygotes, such that adolescents carrying A1 alleles experiencing high negative parenting reported more depressive symptoms but fared better when experiencing low negative parenting. However, the interaction became nonsignificant at age 13, indicating the interaction of TaqIA polymorphism and maternal parenting may vary with development. Also, there was no G × E effect on longitudinal change in depression. The findings provided evidence in support of the differential susceptibility hypothesis and shed light on the potential for dynamic change in gene-environment interactions over development.

  5. Behavioural Medicine Perspectives for Change and Prediction of Oral Hygiene Behaviour : Development and Evaluation of an Individually Tailored Oral Health Educational Program

    OpenAIRE

    Jönsson, Birgitta

    2010-01-01

    This thesis is about a behavioural medicine approach in periodontal treatment and oral hygiene self-care. The aim of this thesis was to develop, describe, and evaluate an individually tailored oral health educational program on oral hygiene behaviour and non-surgical periodontal treatment success, and to determine factors of importance for predicting oral hygiene behaviour. Two separate studies, both conducted at a specialist clinic for periodontics in a Swedish county council are described. ...

  6. Slow identification of facial happiness in early adolescence predicts onset of depression during 8 years of follow-up

    NARCIS (Netherlands)

    Vrijen, Charlotte; Hartman, Catharina A; Oldehinkel, Albertine J

    2016-01-01

    Adolescent onset depression places a high burden on those who suffer from it, and is difficult to treat. An improved understanding of mechanisms underlying susceptibility to adolescent depression may be useful in early detection and as target in treatment. Facial emotion identification bias has been

  7. Low Self-Esteem during Adolescence Predicts Poor Health, Criminal Behavior, and Limited Economic Prospects during Adulthood

    Science.gov (United States)

    Trzesniewski, Kali H.; Donnellan, M. Brent; Moffitt, Terrie E.; Robins, Richard W.; Poulton, Richie; Caspi, Avshalom

    2006-01-01

    Using prospective data from the Dunedin Multidisciplinary Health and Development Study birth cohort, the authors found that adolescents with low self-esteem had poorer mental and physical health, worse economic prospects, and higher levels of criminal behavior during adulthood, compared with adolescents with high self-esteem. The long-term…

  8. Stress-Induced Activation of the HPA Axis Predicts Connectivity between Subgenual Cingulate and Salience Network during Rest in Adolescents

    Science.gov (United States)

    Thomason, Moriah E.; Hamilton, J. Paul; Gotlib, Ian H.

    2011-01-01

    Background: Responses to stress vary greatly in young adolescents, and little is known about neural correlates of the stress response in youth. The purpose of this study was to examine whether variability in cortisol responsivity following a social stress test in young adolescents is associated with altered neural functional connectivity (FC) of…

  9. The Broader Context of Relational Aggression in Adolescent Romantic Relationships: Predictions from Peer Pressure and Links to Psychosocial Functioning

    Science.gov (United States)

    Schad, Megan M.; Szwedo, David E.; Antonishak, Jill; Hare, Amanda; Allen, Joseph P.

    2008-01-01

    The broader context of relational aggression in adolescent romantic relationships was assessed by considering the ways such aggression emerged from prior experiences of peer pressure and was linked to concurrent difficulties in psychosocial functioning. Longitudinal, multi-reporter data were obtained from 97 adolescents and their best friends at…

  10. Prediction of Five Factor Personality Dimensions Through Self- Esteem in Turkish Late Adolescents

    OpenAIRE

    Aslan, Sevda

    2012-01-01

    This study aims to determine the relationship between five factor personality dimensions and self-esteem in terms of how self-esteem predicts five factor personality dimensions. The study group consisted of a total of 122 students 98 of whom were females (80%) and 24 males (19.7 %). Personality Test Based on Adjectives (Bacanlı, İlhan ve Aslan, 2009) and Rosenberg Self-esteem Scale (Rosenberg, 1965; Çuhadaroğlu, 1986) were used as data collection instruments in this study. The data gathered f...

  11. Using theory of planned behavior to predict healthy eating of Danish adolescents

    DEFF Research Database (Denmark)

    Grønhøj, Alice; Bech-Larsen, Tino; Chan, Kara;

    2013-01-01

    Purpose - The objective of the study was to apply the Theory of Planned Behavior to predict Danish adolescents’ behavioural intention for healthy eating. Design/methodology/approach - A cluster sample survey of 410 students aged 11 to 16 years studying in Grade 6 to Grade 10 was conducted......, to a lesser extent, interesting and desirable. Family, TV programmes, and teachers were influential socialization agents. Research limitations – The survey responses may be affected by a social desirability bias. The survey includes a non-probability sample and results may not be generalized to all Danish...

  12. Does Physical Abuse in Early Childhood Predict Substance Use in Adolescence and Early Adulthood?

    OpenAIRE

    Lansford, Jennifer E.; Dodge, Kenneth A.; Pettit, Gregory S.; BATES, JOHN E.

    2010-01-01

    Prospective longitudinal data from 535 families were used to examine parents’ reports of child physical abuse in the first five years of life as a predictor of substance use at ages 12, 16, and 24. Path analyses revealed that physical abuse in the first five years of life predicted subsequent substance use for females but not males. We found a direct effect of early physical abuse on girls’ substance use at age 12 and indirect effects on substance use at age 16 and age 24 through substance us...

  13. Adolescent health in Asia: insights from India.

    Science.gov (United States)

    Basker, Mona M

    2016-08-01

    Adolescents living in the Indian subcontinent form a significant proportion of the general population. India is home to 236 million adolescents, who make up one-fifth of the total population of India. Adolescent health is gradually considered an important issue by the government of India. Awareness is increasing about adolescent needs. Health care professionals in particular are becoming more interested in the specific needs of adolescent age. Adolescent medicine as a subspecialty of pediatrics has also gained importance gradually over the last decade. In a hospital setting, adolescent-specific needs are met, albeit not in a uniform manner in all the health centers. After having been trained in adolescent medicine in India and abroad, I present this paper as a bird's eye view of the practice of adolescent health and medicine in India. PMID:27447203

  14. PRIMEROS INTENTOS HACIA LA OBTENCIÓN DE ÍNDICES PREDICTIVOS EN LA HIPERTENSIÓN ARTERIAL DEL ADOLESCENTE / First attempts to obtain predictive indexes in adolescent hypertension

    Directory of Open Access Journals (Sweden)

    Guillermo Alberto Pérez Fernández

    2011-09-01

    Full Text Available Introduction and Objectives: There are many risk factors for developing hypertension. In the XXI century, smarter ways to investigate are needed, so preventing the turning of an adolescent into a hypertensive adult must be a priority. The aim of this paper is to predict the risk of hypertension onset in adulthood, from cardiovascular tension and risk stratification since adolescence. Methods: A representative sample of 125 adolescents from the project PESESCAD-HTA was studied. They were diagnosed with prehypertension in 2001, and were followed for 8 years (96 months until January 2009. Results: Two predictive indexes were obtained. The first, based on the total cardiovascular risk and the second from the multiplication of these risks with an accuracy index for each of 61.6% and 70.4%, respectively. Conclusions: The index based on the multiplication of cardiovascular risk can predict, with adequate accuracy, the turning of a prehypertensive adolescent into hypertensive once he/she reaches adulthood.

  15. Predicting Metabolic Syndrome in Obese Children and Adolescents: Look, Measure and Ask

    Directory of Open Access Journals (Sweden)

    Nicola Santoro

    2013-02-01

    Full Text Available Objective: To verify in obese children whether or not the presence of i high waist-to-height ratio (WHtR, ii family history for type 2 diabetes (T2D and iii acanthosis nigricans (AN, singularly or together, might predict the occurrence of metabolic syndrome or prediabetes. Methods. 1,080 Italian obese children (567 females were enrolled. Blood pressure, fasting plasma glucose, insulin, and lipids were measured, and oral glucose tolerance test (OGTT was performed. The WHtR was calculated, family history for T2D was assessed, and the presence of AN was noticed. The odds ratios for showing metabolic syndrome and/or prediabetes according to the presence of these features were calculated. Results: The prevalence of metabolic syndrome was 29.2%. AN (OR1.81; p = 0.002 and WHtR higher than 0.60 (OR 2.24; p Conclusions: Three simple actions, i.e., looking at the patient, asking about T2D family history, and measuring WHtR, may represent a powerful tool in the hands of pediatricians to identify obese children with high cardiovascular and metabolic risk.

  16. Identifying Psychosocial Variables That Predict Safer Sex Intentions in Adolescents and Young Adults.

    Science.gov (United States)

    Brüll, Phil; Ruiter, Robert A C; Wiers, Reinout W; Kok, Gerjo

    2016-01-01

    Young people are especially vulnerable to sexually transmitted infections (STIs). The triad of deliberate and effective safer sex behavior encompasses condom use, combined with additional information about a partner's sexual health, and the kind of sex acts usually performed. To identify psychosocial predictors of young people's intentions to have safer sex, as related to this triad, we conducted an online study with 211 sexually active participants aged between 18 and 24 years. Predictors [i.e., perceived behavioral control (PBC), subjective norms, and intention] taken from Fishbein and Ajzen's Reasoned Action Approach (RAA), were combined with more distal variables (e.g., behavioral inhibition, sensation seeking, parental monitoring, and knowledge about STIs). Beyond the highly predictive power of RAA variables, additional variance was explained by the number of instances of unprotected sexual intercourse (SI) during the last 12 months and reasons for using barrier protection during first SI. In particular, past condom non-use behavior moderated PBC related to intended condom use. Further, various distal variables showed significant univariate associations with intentions related to the three behaviors of interest. It may, therefore, be helpful to include measures of past behavior as well as certain additional distal variables in future safer sex programs designed to promote health-sustaining sexual behavior. PMID:27148520

  17. Identifying psychosocial variables that predict safer-sex intentions in adolescents and young adults

    Directory of Open Access Journals (Sweden)

    Phil eBrüll

    2016-04-01

    Full Text Available Young people are especially vulnerable to sexually transmitted infections. The triad of deliberate and effective safer-sex behavior encompasses condom use, combined with additional information about a partner’s sexual health, and the kind of sex acts usually performed. To identify psychosocial predictors of young people’s intentions to have safer sex, as related to this triad we conducted an online study with 211 sexually active participants aged between 18 and 24 years. Predictors (i.e. perceived behavioural control, subjective norms and intention taken from Fishbein and Ajzen’s Reasoned Action Approach (RAA, were combined with more distal variables (e.g. behavioral inhibition, sensation seeking, parental monitoring, and knowledge about sexually transmitted infections. Beyond the highly predictive power of RAA variables, additional variance was explained by the number of instances of unprotected sexual intercourse during the last twelve months and reasons for using barrier protection during first sexual intercourse. In particular, past condom nonuse behavior moderated perceived behavioral control related to intended condom use. Further, various distal variables showed significant univariate associations with intentions related to the three behaviors of interest. It may, therefore, be helpful to include measures of past behavior as well as certain additional distal variables in future safer-sex programs designed to promote health sustaining sexual behavior.

  18. Risk Score Model for Predicting Sonographic Non-Alcoholic Fatty Liver Disease in Children and Adolescents

    Directory of Open Access Journals (Sweden)

    Parinaz Poursafa

    2011-06-01

    Full Text Available Objective: This study aimed to develop and test the validity of a risk score to be used as a simple tool to identify those children at high risk of sonographic non-alcoholic fatty liver disease (NAFLD. Methods:This cross-sectional study was conducted among 962 participants aged 6-18 years in Isfahan, Iran. They consisted of three groups of nearly equal number of normal-weight, overweight and obese individuals. Coefficients of the logistic regression models were used to assign a score value for each variable and the composite sonographic NAFLD risk score was calculated as the sum of those scores. Performance of model was assessed by receiver operating characteristic (ROC curve procedure. Findings:Data of 931 participants was included in the analysis. The sonographic findings of 16.8% of participants were compatible with NAFLD. Age, sex, body mass index, waist circumference and serum triglycerides level were diagnosed as factors associated with NAFLD. The risk score was calculated as 50 for sonographic NAFLD. Conclusion:This study, to the best of our knowledge is the first of its kind in the pediatric age group, focuses on predicting sonographic NAFLD from easily-measured factors. It may suggest an association of hypertriglyceridemic-waist phenotype with NAFLD in the pediatric age group.

  19. Self-discipline outdoes IQ in predicting academic performance of adolescents.

    Science.gov (United States)

    Duckworth, Angela L; Seligman, Martin E P

    2005-12-01

    In a longitudinal study of 140 eighth-grade students, self-discipline measured by self-report, parent report, teacher report, and monetary choice questionnaires in the fall predicted final grades, school attendance, standardized achievement-test scores, and selection into a competitive high school program the following spring. In a replication with 164 eighth graders, a behavioral delay-of-gratification task, a questionnaire on study habits, and a group-administered IQ test were added. Self-discipline measured in the fall accounted for more than twice as much variance as IQ in final grades, high school selection, school attendance, hours spent doing homework, hours spent watching television (inversely), and the time of day students began their homework. The effect of self-discipline on final grades held even when controlling for first-marking-period grades, achievement-test scores, and measured IQ. These findings suggest a major reason for students falling short of their intellectual potential: their failure to exercise self-discipline. PMID:16313657

  20. Personality predictors of successful development: toddler temperament and adolescent personality traits predict well-being and career stability in middle adulthood.

    Science.gov (United States)

    Blatný, Marek; Millová, Katarína; Jelínek, Martin; Osecká, Terezie

    2015-01-01

    The aim of the study was to predict both adaptive psychological functioning (well-being) and adaptive social functioning (career stability) in middle adulthood based on behaviors observed in toddlerhood and personality traits measured in adolescence. 83 people participated in an ongoing longitudinal study started in 1961 (58% women). Based on children's behavior in toddlerhood, three temperamental dimensions were identified - positive affectivity, negative affectivity and disinhibition. In adolescence, extraversion and neuroticism were measured at the age of 16 years. Various aspects of well-being were used as indicators of adaptive psychological functioning in adulthood: life satisfaction, self-esteem and self-efficacy. Career stability was used as an indicator of adaptive social functioning. Job careers of respondents were characterized as stable, unstable or changeable. Extraversion measured at the age of 16 proved to be the best predictor of well-being indicators; in case of self-efficacy it was also childhood disinhibition. Extraversion in adolescence, childhood disinhibition and negative affectivity predicted career stability. Findings are discussed in the context of a theoretical framework of higher order factors of the Big Five personality constructs, stability and plasticity.

  1. Personality predictors of successful development: toddler temperament and adolescent personality traits predict well-being and career stability in middle adulthood.

    Directory of Open Access Journals (Sweden)

    Marek Blatný

    Full Text Available The aim of the study was to predict both adaptive psychological functioning (well-being and adaptive social functioning (career stability in middle adulthood based on behaviors observed in toddlerhood and personality traits measured in adolescence. 83 people participated in an ongoing longitudinal study started in 1961 (58% women. Based on children's behavior in toddlerhood, three temperamental dimensions were identified - positive affectivity, negative affectivity and disinhibition. In adolescence, extraversion and neuroticism were measured at the age of 16 years. Various aspects of well-being were used as indicators of adaptive psychological functioning in adulthood: life satisfaction, self-esteem and self-efficacy. Career stability was used as an indicator of adaptive social functioning. Job careers of respondents were characterized as stable, unstable or changeable. Extraversion measured at the age of 16 proved to be the best predictor of well-being indicators; in case of self-efficacy it was also childhood disinhibition. Extraversion in adolescence, childhood disinhibition and negative affectivity predicted career stability. Findings are discussed in the context of a theoretical framework of higher order factors of the Big Five personality constructs, stability and plasticity.

  2. Does Playing Sports Video Games Predict Increased Involvement in Real-Life Sports Over Several Years Among Older Adolescents and Emerging Adults?

    Science.gov (United States)

    Adachi, Paul J C; Willoughby, Teena

    2016-02-01

    Given the extreme popularity of video games among older adolescents and emerging adults, the investigation of positive outcomes of video game play during these developmental periods is crucial. An important direction for research in this area is the investigation of a link between sports video game play and involvement in real-life sports among youth. Yet, this association has not been examined in the long-term among older adolescents and emerging adults, and thus represents an exciting new area for discovery. The primary goal of the current study, therefore, was to examine the long-term association between sports video game play and involvement in real-life sports clubs among older adolescents and emerging adults. In addition, we examined whether self-esteem was an underlying mechanism of this longitudinal association. We surveyed older adolescents and emerging adults (N = 1132; 70.6 % female; M age = 19.06 years, range of 17-25 years at the first assessment) annually over 3 years about their video game play, self-esteem, and involvement in real-life sports. We found a long-term predictive effect of sports video game play on increased involvement in real-life sports over the 3 years. Furthermore, we demonstrated that self-esteem was an underlying mechanism of this long-term association. Our findings make an important contribution to an emerging body of literature on the positive outcomes of video game play, as they suggest that sports video game play may be an effective tool to promote real-life sports participation and physical activity among older adolescents and emerging adults.

  3. Does Playing Sports Video Games Predict Increased Involvement in Real-Life Sports Over Several Years Among Older Adolescents and Emerging Adults?

    Science.gov (United States)

    Adachi, Paul J C; Willoughby, Teena

    2016-02-01

    Given the extreme popularity of video games among older adolescents and emerging adults, the investigation of positive outcomes of video game play during these developmental periods is crucial. An important direction for research in this area is the investigation of a link between sports video game play and involvement in real-life sports among youth. Yet, this association has not been examined in the long-term among older adolescents and emerging adults, and thus represents an exciting new area for discovery. The primary goal of the current study, therefore, was to examine the long-term association between sports video game play and involvement in real-life sports clubs among older adolescents and emerging adults. In addition, we examined whether self-esteem was an underlying mechanism of this longitudinal association. We surveyed older adolescents and emerging adults (N = 1132; 70.6 % female; M age = 19.06 years, range of 17-25 years at the first assessment) annually over 3 years about their video game play, self-esteem, and involvement in real-life sports. We found a long-term predictive effect of sports video game play on increased involvement in real-life sports over the 3 years. Furthermore, we demonstrated that self-esteem was an underlying mechanism of this long-term association. Our findings make an important contribution to an emerging body of literature on the positive outcomes of video game play, as they suggest that sports video game play may be an effective tool to promote real-life sports participation and physical activity among older adolescents and emerging adults. PMID:26033045

  4. Trait-like brain activity during adolescence predicts anxious temperament in primates.

    Directory of Open Access Journals (Sweden)

    Andrew S Fox

    Full Text Available Early theorists (Freud and Darwin speculated that extremely shy children, or those with anxious temperament, were likely to have anxiety problems as adults. More recent studies demonstrate that these children have heightened responses to potentially threatening situations reacting with intense defensive responses that are characterized by behavioral inhibition (BI (inhibited motor behavior and decreased vocalizations and physiological arousal. Confirming the earlier impressions, data now demonstrate that children with this disposition are at increased risk to develop anxiety, depression, and comorbid substance abuse. Additional key features of anxious temperament are that it appears at a young age, it is a stable characteristic of individuals, and even in non-threatening environments it is associated with increased psychic anxiety and somatic tension. To understand the neural underpinnings of anxious temperament, we performed imaging studies with 18-fluoro-deoxyglucose (FDG high-resolution Positron Emission Tomography (PET in young rhesus monkeys. Rhesus monkeys were used because they provide a well validated model of anxious temperament for studies that cannot be performed in human children. Imaging the same animal in stressful and secure contexts, we examined the relation between regional metabolic brain activity and a trait-like measure of anxious temperament that encompasses measures of BI and pituitary-adrenal reactivity. Regardless of context, results demonstrated a trait-like pattern of brain activity (amygdala, bed nucleus of stria terminalis, hippocampus, and periaqueductal gray that is predictive of individual phenotypic differences. Importantly, individuals with extreme anxious temperament also displayed increased activity of this circuit when assessed in the security of their home environment. These findings suggest that increased activity of this circuit early in life mediates the childhood temperamental risk to develop anxiety and

  5. Trait-like brain activity during adolescence predicts anxious temperament in primates.

    Science.gov (United States)

    Fox, Andrew S; Shelton, Steven E; Oakes, Terrence R; Davidson, Richard J; Kalin, Ned H

    2008-01-01

    Early theorists (Freud and Darwin) speculated that extremely shy children, or those with anxious temperament, were likely to have anxiety problems as adults. More recent studies demonstrate that these children have heightened responses to potentially threatening situations reacting with intense defensive responses that are characterized by behavioral inhibition (BI) (inhibited motor behavior and decreased vocalizations) and physiological arousal. Confirming the earlier impressions, data now demonstrate that children with this disposition are at increased risk to develop anxiety, depression, and comorbid substance abuse. Additional key features of anxious temperament are that it appears at a young age, it is a stable characteristic of individuals, and even in non-threatening environments it is associated with increased psychic anxiety and somatic tension. To understand the neural underpinnings of anxious temperament, we performed imaging studies with 18-fluoro-deoxyglucose (FDG) high-resolution Positron Emission Tomography (PET) in young rhesus monkeys. Rhesus monkeys were used because they provide a well validated model of anxious temperament for studies that cannot be performed in human children. Imaging the same animal in stressful and secure contexts, we examined the relation between regional metabolic brain activity and a trait-like measure of anxious temperament that encompasses measures of BI and pituitary-adrenal reactivity. Regardless of context, results demonstrated a trait-like pattern of brain activity (amygdala, bed nucleus of stria terminalis, hippocampus, and periaqueductal gray) that is predictive of individual phenotypic differences. Importantly, individuals with extreme anxious temperament also displayed increased activity of this circuit when assessed in the security of their home environment. These findings suggest that increased activity of this circuit early in life mediates the childhood temperamental risk to develop anxiety and depression. In

  6. MRI to predict prostate growth and development in children, adolescents and young adults

    Energy Technology Data Exchange (ETDEWEB)

    Ren, Jing; Liu, Huijia; Wen, Didi; Huang, Xufang; Ren, Fang; Huan, Yi [Fourth Military Medical University, Department of Radiology, Xijing Hospital, Xi' an City (China); Wang, He [Fourth Military Medical University, Department of Urology, Tangdu Hospital, Xi' an City (China)

    2014-08-06

    The purpose of this study was to investigate the use of MRI in predicting prostate growth and development. A total of 1,500 healthy male volunteers who underwent MRI of the pelvis were included in this prospective study. Subjects were divided into five groups according to age (group A, 2-5 years; group B, 6-10 years; group C, 11-15 years; group D, 16-20 years; group E, 21-25 years). Total prostate volume (TPV) as well as prostate central zone (CZ) and peripheral zone (PZ) were measured and evaluated on MRI. Data of the different groups were compared using variance analysis, Scheffe's method, Kruskal-Wallis H-test, and Pearson's correlation. Statistical significance was inferred at P < 0.05. In groups A and B, the prostates were barely visible. In group C, although TPV was measured, it was hard to distinguish CZ and PZ. In group D, 136 CZ and PZ were clearly visible. In group E, 377 CZ and PZ were clearly visible on T2-weighted imaging (T2WI). The median TPVs of groups A, B, C, D, and E were 0.00 cm{sup 3}, 0.05 cm{sup 3}, 2.83 cm{sup 3}, 8.32 cm{sup 3,} and 11.56 cm{sup 3}, respectively, and the median prostate development scores were 0.08, 0.69, 1.56, 2.38, and 2.74, respectively. Both TPVs and zonal anatomy scores varied significantly among the five groups (P = 0.000). TPV and zonal anatomy score increased with increasing age. MRI provides a reliable quantitative reference for prostate growth and development. (orig.)

  7. 4Ps medicine of the fatty liver: the research model of predictive, preventive, personalized and participatory medicine-recommendations for facing obesity, fatty liver and fibrosis epidemics.

    Science.gov (United States)

    Trovato, Francesca Maria; Catalano, Daniela; Musumeci, Giuseppe; Trovato, Guglielmo M

    2014-01-01

    Relationship between adipose tissue and fatty liver, and its possible evolution in fibrosis, is supported by clinical and research experience. Given the multifactorial pathogenesis of non-alcoholic fatty liver disease (NAFLD), treatments for various contributory risk factors have been proposed; however, there is no single validated therapy or drug association recommended for all cases which can stand alone. Mechanisms, diagnostics, prevention and treatment of obesity, fatty liver and insulin resistance are displayed along with recommendations and position points. Evidences and practice can get sustainable and cost-benefit valuable outcomes by participatory interventions. These recommendations can be enhanced by comprehensive research projects, addressed to societal issues and innovation, market appeal and industry development, cultural acceptance and sustainability. The basis of participatory medicine is a greater widespread awareness of a condition which is both a disease and an easy documented and inclusive clue for associated diseases and unhealthy lifestyle. This model is suitable for addressing prevention and useful for monitoring improvement, worsening and adherence with non-invasive imaging tools which allow targeted approaches. The latter include health psychology and nutritional and physical exercise prescription expertise disseminated by continuous medical education but, more important, by concrete curricula for training undergraduate and postgraduate students. It is possible and recommended to do it by early formal teaching of ultrasound imaging procedures and of practical lifestyle intervention strategies, including approaches aimed to healthier fashion suggestions. Guidelines and requirements of research project funding calls should be addressed also to NAFLD and allied conditions and should encompass the goal of training by research and the inclusion of participatory medicine topics. A deeper awareness of ethics of competences in health professionals

  8. What Predicts a Good Adolescent to Adult Transition in ADHD? The Role of Self-Reported Resilience

    DEFF Research Database (Denmark)

    Schei, Jorun; Nøvik, Torunn Stene; Thomsen, Per Hove;

    2015-01-01

    resilience characteristics during adolescence protected against psychosocial impairment, depression, and anxiety 3 years later. Self-reported protective factors were used as baseline measures in the assessment of 190 clinically referred adolescents with ADHD. A semi-structured diagnostic interview......OBJECTIVE: ADHD is a disorder associated with impairment and comorbid psychiatric problems in young adulthood; therefore, factors that may imply a more favorable outcome among adolescents with ADHD are of interest. METHOD: This study used a longitudinal design to assess whether adolescent personal...... was performed at the follow-up. RESULTS: In a group of youth with ADHD, personal resilience characteristics were associated with better psychosocial functioning in young adulthood, and less depression and anxiety. CONCLUSION: Although further research is needed, these results indicate that personal resilience...

  9. Response time variability and response inhibition predict affective problems in adolescent girls, not in boys : the TRAILS study

    NARCIS (Netherlands)

    van Deurzen, Patricia A. M.; Buitelaar, Jan K.; Brunnekreef, J. Agnes; Ormel, Johan; Minderaa, Ruud B.; Hartman, Catharina A.; Huizink, Anja C.; Speckens, Anne E. M.; Oldehinkel, A. J.; Slaats-Willemse, Dorine I. E.

    2012-01-01

    The present study examines the relationship between neurocognitive functioning and affective problems through adolescence, in a cross-sectional and longitudinal perspective. Baseline response speed, response speed variability, response inhibition, attentional flexibility and working memory were asse

  10. What predicts sex partner age differences among African American youth? A longitudinal study from adolescence to young adulthood

    OpenAIRE

    Bauermeister, José A.; Zimmerman, Marc A; Caldwell, Cleopatra; Xue, Yange; Gee, Gilbert C.

    2010-01-01

    Partner age is associated with youth’s sex risk behaviors and sexually transmitted infections. At present, however, we do not know whether the co-occurrence of other risk behaviors is associated with having older sex partners during adolescence and young adulthood. Using growth curve modeling, we first described the shape of the age difference between participants and their sex partners across adolescence and young adulthood in a sample of African American youth. Second, we tested whether thi...

  11. An extended version of the theory of planned behaviour: the role of self-efficacy and past behaviour in predicting the physical activity of Chinese adolescents.

    Science.gov (United States)

    Wang, Lijuan; Zhang, Ying

    2016-01-01

    This study aimed to use an extended theory of planned behaviour (TPB), which incorporated additional self-efficacy and past behaviour, to predict the intention to engage in moderate-to-vigorous physical activity (MVPA) and the MVPA level of Chinese adolescents. Questionnaires that focused on MVPA, attitude, subjective norm, perceived behavioural control (PBC), self-efficacy and past behaviour related to the MVPA engagement were administered to a sample of 488 young people. Multiple regression analyses provided moderate support for TPB. Three TPB constructs predicted 28.7% of the variance in intentions to engage in MVPA, and that PBC, but not intention, explained 3.4% of the variance in MVPA. Self-efficacy significantly affected intention and behaviour over and above the influence of TPB. Past behaviour had a small but significant improvement in the prediction of intention, but no improvement in the prediction of MVPA. Based on the results, interventions should target adolescent self-efficacy and PBC in physical activity participation. PMID:26148128

  12. Can the Health of the Nation Outcome Scales for Children and Adolescents predict the necessity of inpatient stay during assertive community treatment?

    Science.gov (United States)

    Urben, Sébastien; Mantzouranis, Gregory; Baier, Vanessa; Halfon, Olivier; Villard, Eva; Holzer, Laurent

    2016-08-30

    Understanding the trajectories of youths within Child and Adolescents Mental Health Service (CAMHS) is of primary importance. Our objective is to assess the usefulness of the Health of the Nation Outcome Scales for Children and Adolescents (HoNOSCA) to predict inpatient (IP) stay for youths followed by assertive community treatment (ACT) teams. 82 youths followed exclusively by ACT and 42 who needed IP were assessed with the HoNOSCA at admission to the program. The HoNOSCA allowed the computing of three scores: a total score, an externalizing symptoms (Ext) score and an emotional problems (Emo) score. Logistic regressions revealed that the three HoNOSCA scores at admission of ACT predicted later need for hospitalization. Using ROC curve analyses, we set up cut off scores with appropriate sensitivity and specificity for the HoNOSCA Total and Ext to optimally predict the need for hospitalization. This study revealed that the HoNOSCA may be a useful tool to predict the need for later IP during ACT. Such knowledge is important to set up the best therapeutic strategies. PMID:27341331

  13. An extended version of the theory of planned behaviour: the role of self-efficacy and past behaviour in predicting the physical activity of Chinese adolescents.

    Science.gov (United States)

    Wang, Lijuan; Zhang, Ying

    2016-01-01

    This study aimed to use an extended theory of planned behaviour (TPB), which incorporated additional self-efficacy and past behaviour, to predict the intention to engage in moderate-to-vigorous physical activity (MVPA) and the MVPA level of Chinese adolescents. Questionnaires that focused on MVPA, attitude, subjective norm, perceived behavioural control (PBC), self-efficacy and past behaviour related to the MVPA engagement were administered to a sample of 488 young people. Multiple regression analyses provided moderate support for TPB. Three TPB constructs predicted 28.7% of the variance in intentions to engage in MVPA, and that PBC, but not intention, explained 3.4% of the variance in MVPA. Self-efficacy significantly affected intention and behaviour over and above the influence of TPB. Past behaviour had a small but significant improvement in the prediction of intention, but no improvement in the prediction of MVPA. Based on the results, interventions should target adolescent self-efficacy and PBC in physical activity participation.

  14. Adolescent Alcohol Exposure Amplifies the Incentive Value of Reward-Predictive Cues Through Potentiation of Phasic Dopamine Signaling.

    Science.gov (United States)

    Spoelder, Marcia; Tsutsui, Kimberly T; Lesscher, Heidi M B; Vanderschuren, Louk J M J; Clark, Jeremy J

    2015-12-01

    Adolescent alcohol use remains a major public health concern due in part to well-established findings implicating the age of onset in alcohol use in the development of alcohol use disorders and persistent decision-making deficits in adults. We have previously demonstrated that moderate adolescent alcohol consumption in rats promotes suboptimal decision making and an associated perturbation in mesolimbic dopamine transmission in adulthood. Dopamine-dependent incentive learning processes are an integral component of value-based decision making and a fundamental element to many theoretical accounts of addiction. Thus we tested the hypothesis that adolescent alcohol use selectively alters incentive learning processes through perturbation of mesolimbic dopamine systems. To assess incentive learning, behavioral and neurochemical measurements were made during the acquisition, maintenance, extinction, and reacquisition of a Pavlovian conditioned approach procedure in adult rats with a history of adolescent alcohol consumption. We show that moderate adolescent alcohol consumption potentiates stimulus-evoked phasic dopamine transmission, measured in vivo by fast-scan cyclic voltammetry, in adulthood and biases individuals toward a dopamine-dependent incentive learning strategy. Moreover, we demonstrate that animals exposed to alcohol in adolescence are more sensitive to an unexpected variation in reward outcomes. This pattern of phasic dopamine signaling and the associated bias in learning may provide a mechanism for the well-documented vulnerability of individuals with early-life alcohol use for alcohol use disorders in adulthood.

  15. International note: Prediction of mathematics work ethic and performance from behavioral, normative, and control beliefs among Qatari adolescents.

    Science.gov (United States)

    Areepattamannil, Shaljan; Abdelfattah, Faisal; Mahasneh, Randa Ali; Khine, Myint Swe; Welch, Anita G; Melkonian, Michael; Al Nuaimi, Samira Ahmed

    2016-01-01

    Over half-a-million adolescents take part in each cycle of the Program for International Student Assessment (PISA). Yet often, researchers and policy makers across the globe tend to focus their attention primarily on the academic trajectories of adolescents hailing from highly successful education systems. Hence, a vast majority of the adolescent population who regionally and globally constitute the 'long tail of underachievement' often remain unnoticed and underrepresented in the growing literature on adolescents' academic trajectories. The present study, therefore, explored the relations of dispositions toward mathematics, subjective norms in mathematics, and perceived control of success in mathematics to mathematics work ethic as well as mathematics performance; and the mediational role of mathematics work ethic in the association between dispositional, normative, and control beliefs and mathematics performance among adolescents in one of the lowest performing education systems, Qatar. Structural equation modeling (SEM) analyses revealed that Qatari adolescents' dispositional, normative, and control beliefs about mathematics were significantly associated with their mathematics work ethic and mathematics performance, and mathematics work ethic significantly mediated the relationship between dispositional, normative, and control beliefs about mathematics and mathematics performance. However, multi-group SEM analyses indicated that these relationships were not invariant across the gender and the SES groups.

  16. Lower Psychological Well-Being and Excessive Sexual Interest Predict Symptoms of Compulsive Use of Sexually Explicit Internet Material Among Adolescent Boys.

    Science.gov (United States)

    Doornwaard, Suzan M; van den Eijnden, Regina J J M; Baams, Laura; Vanwesenbeeck, Ine; ter Bogt, Tom F M

    2016-01-01

    Although a growing body of literature addresses the effects of young people's use of sexually explicit Internet material, research on the compulsive use of this type of online content among adolescents and its associated factors is largely lacking. This study investigated whether factors from three distinct psychosocial domains (i.e., psychological well-being, sexual interests/behaviors, and impulsive-psychopathic personality) predicted symptoms of compulsive use of sexually explicit Internet material among adolescent boys. Links between psychosocial factors and boys' compulsive use symptoms were analyzed both cross-sectionally and longitudinally with compulsive use symptoms measured 6 months later (T2). Data were used from 331 Dutch boys (M age = 15.16 years, range 11-17) who indicated that they used sexually explicit Internet material. The results from negative binomial regression analyses indicated that lower levels of global self-esteem and higher levels of excessive sexual interest concurrently predicted boys' symptoms of compulsive use of sexually explicit Internet material. Longitudinally, higher levels of depressive feelings and, again, excessive sexual interest predicted relative increases in compulsive use symptoms 6 months later. Impulsive and psychopathic personality traits were not uniquely related to boys' symptoms of compulsive use of sexually explicit Internet material. Our findings, while preliminary, suggest that both psychological well-being factors and sexual interests/behaviors are involved in the development of compulsive use of sexually explicit Internet material among adolescent boys. Such knowledge is important for prevention and intervention efforts that target the needs of specific problematic users of sexually explicit Internet material.

  17. Waist-to-Height Ratio Is a Better Anthropometric Index than Waist Circumference and BMI in Predicting Metabolic Syndrome among Obese Mexican Adolescents

    Directory of Open Access Journals (Sweden)

    Edel Rafael Rodea-Montero

    2014-01-01

    Full Text Available Objective. To identify the degree of association between anthropometric indices and components of metabolic syndrome (MS and to determine optimal cut-off points of these indices for predicting MS in obese adolescents. Methods. A cross-sectional study with a sample of (n=110 Mexican obese adolescents grouped by sex and the presence/absence of MS. BMI percentile, waist circumference (WC, and waist-to-height ratio (WHtR were tested. ROC curves of the anthropometric indices were created to identify whether an index was a significant predictor of MS. Results. BMI percentile, WC, and WHtR were significantly correlated with systolic and diastolic blood pressure. As predictors of MS overall patients, the BMI percentile generated an area under curve (AUC of 0.651 (P=0.008, cut-off point above the 99th percentile. WC generated an AUC of 0.704 (P<0.001, cut-off point of ≥90 cm. WHtR demonstrated an AUC of 0.652 (P=0.008, cut-off point of 0.60. WHtR ≥0.62 and WHtR ≥0.61 generate AUC of 0.737 (P=0.006 and AUC of 0.717 (P=0.014 for predicting hypertension and insulin resistance, respectively, in females. Conclusion. WHtR is a better tool than WC and BMI for identifying cardiometabolic risk. The overall criterion (WHtR ≥ 0.6 could be appropriate for predicting MS in obese Mexican adolescents.

  18. Predicting volumes of metabolically important whole-body adipose tissue compartments in overweight and obese adolescents by different MRI approaches and anthropometry

    International Nuclear Information System (INIS)

    Objectives: To evaluate 5-slice stack/single-slice MRI approaches and anthropometric measures as predictors for metabolically relevant whole-body adipose tissue (AT) compartments in overweight/obese adolescents. Methods: Forty adolescents (22 males, age 11.4–16.1 years) were included with a BMI above the 90th percentile. Volumes of whole-body AT compartments, i.e. total AT (TAT), subcutaneous AT (SCAT) and visceral AT (VAT), were determined using a breath-hold T1-weighted-FSE-MR-sequence and semi-automated segmentation serving as the gold standard. SCAT, VAT and TAT was estimated by either axially oriented single-slices or 5-slice-stacks centred at specific anatomic landmarks (umbilicus, head of femur and humerus). Furthermore, anthropometric measures were also evaluated as predictors of whole-body AT compartments. Results: Strong correlations were found for both genders between TAT/SCAT and single-slice evaluation (e.g. whole-body SCAT-SCAT at umbilicus level: r = 0.91 (m), r = 0.92 (f)) or anthropometry (SCAT-BMI: r = 0.93 (m, f)). VAT was correlated to VAT at umbilicus (r = 0.71 (m), r = 0.94 (f)) but only weakly to anthropometry. Conclusions: Anthropometric measures and single-slice MRI can accurately predict TAT/SCAT which cannot be improved by evaluation of 5-slice stacks. Prediction of VAT by 5-slice stack/single-slice MRI protocols seems only to be accurate in females. Anthropometry cannot be reliably used for prediction of VAT in both genders. Thus, MRI seems to be necessary for quantification of VAT in overweight/obese adolescents of both genders.

  19. Lower Psychological Well-Being and Excessive Sexual Interest Predict Symptoms of Compulsive Use of Sexually Explicit Internet Material Among Adolescent Boys.

    Science.gov (United States)

    Doornwaard, Suzan M; van den Eijnden, Regina J J M; Baams, Laura; Vanwesenbeeck, Ine; ter Bogt, Tom F M

    2016-01-01

    Although a growing body of literature addresses the effects of young people's use of sexually explicit Internet material, research on the compulsive use of this type of online content among adolescents and its associated factors is largely lacking. This study investigated whether factors from three distinct psychosocial domains (i.e., psychological well-being, sexual interests/behaviors, and impulsive-psychopathic personality) predicted symptoms of compulsive use of sexually explicit Internet material among adolescent boys. Links between psychosocial factors and boys' compulsive use symptoms were analyzed both cross-sectionally and longitudinally with compulsive use symptoms measured 6 months later (T2). Data were used from 331 Dutch boys (M age = 15.16 years, range 11-17) who indicated that they used sexually explicit Internet material. The results from negative binomial regression analyses indicated that lower levels of global self-esteem and higher levels of excessive sexual interest concurrently predicted boys' symptoms of compulsive use of sexually explicit Internet material. Longitudinally, higher levels of depressive feelings and, again, excessive sexual interest predicted relative increases in compulsive use symptoms 6 months later. Impulsive and psychopathic personality traits were not uniquely related to boys' symptoms of compulsive use of sexually explicit Internet material. Our findings, while preliminary, suggest that both psychological well-being factors and sexual interests/behaviors are involved in the development of compulsive use of sexually explicit Internet material among adolescent boys. Such knowledge is important for prevention and intervention efforts that target the needs of specific problematic users of sexually explicit Internet material. PMID:26208829

  20. Callous-Unemotional Traits Trajectories Interact with Earlier Conduct Problems and Executive Control to Predict Violence and Substance Use Among High Risk Male Adolescents.

    Science.gov (United States)

    Baskin-Sommers, Arielle R; Waller, Rebecca; Fish, Ari M; Hyde, Luke W

    2015-11-01

    Callous-unemotional (CU) traits, conduct problems (CP), and deficits in executive control are all linked to the development of more severe antisocial behavior, including violence and substance use. Though previous research has examined the impact of these factors on antisocial outcomes, little work has examined trajectories of CU traits across adolescence and how these trajectories predict greater antisocial behavior in adulthood. Moreover, no study has assessed how severity of early CP and executive control may exacerbate these pathways and increase risk for later violence and substance use. The current study (a) identified trajectories of CU traits among a large, high-risk sample of adolescent males, (b) examined the relationship between CU traits trajectories and future violence and substance use, and (c) examined whether early CP and executive control moderated the effects of a high CU traits trajectory membership and high CP on violence and substance use. Results indicated that: (a) CU traits could be grouped into three stable trajectories across adolescence, (b) the 'high' CU traits trajectory, particularly in the presence of 'elevated' CP, was related to higher violence and substance use, over and above a variety of environmental risk factors, and (c) the effects the 'high' CU traits trajectory on both violence and substance and in the presence of 'elevated' CP was stronger among youth with high executive control. These findings highlight the utility of identifying subgroups of youth who differ on trajectories of CU traits for understanding the development and maintenance of severe antisocial behavior.

  1. Predictive Medicine for Chronic Patients in an Integrated Care Scenario. Chronic Obstructive Pulmonary Disease as Use Case

    OpenAIRE

    Cano Franco, Isaac

    2014-01-01

    Tesi realitzada a l'Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS) BACKGROUND The epidemics of non-communicable diseases and the need for cost-containment are triggering a profound reshaping of healthcare delivery toward adoption of the Chronic Care model, involving deployment of integrated care services (ICS) with the support of information and communication technologies (ICS-ICT). In this scenario, emerging systems medicine, with a holistic mechanism-based approa...

  2. Artificial Intelligence and Expert Systems in Medicine and Their Ability to Prediction as Therapy Planning Systems by CADIAG-2 Algorithm

    Directory of Open Access Journals (Sweden)

    Mohammad Madadpour Inallou

    2012-10-01

    Full Text Available Expert Systems in Medicine is a collection, storage, retrieval, communication and processing of medical data for the purposes of interpretation, inference, decision-support, research and so other purposes in medicine. Expert System is an interactive computer-based decision tool that uses both facts and heuristics to solve difficult decision problems based on knowledge acquired from an expert. Expert systems provide expert advice and guidance in a wide variety of activities, from computer diagnosis to delicate medical surgery and so more other. CADIAG-2 is a well known rule-based medical expert system aimed at providing support in medical diagnose in the field of internal medicine. This paper employs CADIAG-2 fuzzy set theory and fuzzy logic to formalize medical entities and relationships and uses a large collection of IF-THEN rules to represent uncertain relationships between distinct medical entities. This paper is organized as follows: At first, the introduction and fundamental of CADIAG-2, in second step notation and preliminary definitions is regarded, and in third part the Algorithm will be consider, and the final step is discussed about satisfiablity and Unsatisfiable of CADIAG-2 sets.

  3. Adolescent health care education and training: insights from Israel.

    Science.gov (United States)

    Kerem, Nogah C; Hardoff, Daniel

    2016-08-01

    There is a growing need for health care professionals to extend their knowledge in adolescent health care. Formal training curricula in adolescent medicine have been established in the United States, Canada, and Australia, yet many other countries have developed shorter training programs to enable interested physicians to further pursue knowledge and practical experience in delivering improved quality health care for adolescents. The Israeli experience in building an infrastructure that allows students and physicians to learn about adolescent medicine and to train in the field is described. It includes a series of lectures and seminars for medical students during medical school and at the clinical rotations in pediatric wards; the development of hospital-based and community-based multidisciplinary adolescent health services where residents can practice adolescent health care; a 3-year diploma course in adolescent medicine for specialists in pediatrics and family medicine; mini courses in adolescent medicine for pediatricians and family practitioners working in community settings; and a simulated patient-based program regarding communication with adolescents, aimed for all professional levels - medical students, residents, and specialists. This infrastructure has been developed to create a leading group of physicians, who are able to operate adolescent clinics and to teach adolescent medicine. Recently, a formal fellowship program in adolescent medicine has been approved by the Scientific Council of the Israel Medical Association. The Israeli experience described here could be applied in countries, where formal training programs in adolescent health care are not yet established. PMID:27341557

  4. Nuclear Medicine

    Science.gov (United States)

    ... Parents/Teachers Resource Links for Students Glossary Nuclear Medicine What is nuclear medicine? What are radioactive tracers? ... funded researchers advancing nuclear medicine? What is nuclear medicine? Nuclear medicine is a medical specialty that uses ...

  5. 中西医联合治疗青少年抑郁症疗效观察%Effect observation on treating adolescent depressive disorder in the integrative medicine

    Institute of Scientific and Technical Information of China (English)

    叶沐镕

    2013-01-01

      目的:探求中西医联合治疗青少年抑郁症的疗效是否优于单独运用西医治疗.方法:将78例青少年抑郁症患者随机分为观察组和对照组,两组各39例,观察组服用舍曲林加中药汤剂,而对照组只应用舍曲林.采用汉密尔顿抑郁量表(HAMD)评定临床疗效.结果:观察组治疗有效率为94.44%,对照组有效率为78.38%.两组治疗前 HAMD 得分无显著差异,但治疗后2周、1个月、2个月后观察组减分率显著高于对照组.结论:单用西药治疗青少年抑郁症有一定疗效,但中西医联合治疗具有起效快、疗效稳定和持续时间长的优势,更利于青少年的人格发展和身心健康.%Objective: To compare the efficacies between the integrative medicine and modern medicine alone on adolescent depression disorder, to optimize the treatment of adolescent depression. Methods:78 depressed adolescent patients were randomly divided into the treated group and the control group, 39 patients in each group. Patients in the treated group were given sertraline combined with Chinese decoction, while the control group patients took only sertraline. Hamilton Depression Rating Scale (HAMD) was applied to evaluate the clinical efficacy. Results: The total effective rate in the treated group was 94.44%, while that in the control group was only 78.38%. No significant differences were detected in HAMD score before treatment, but reduction rate in the treated group was significantly higher than that in the control group two weeks, one month, and two months after the treatment. Conclusion: Western medicine treatment only had a certain effect on adolescents’ depression, but the integrative medicine had advantages of rapid onset, stable efficacy and long duration. The integrated therapy is more conducive to the character development and physical and mental health of young people.

  6. Major depression in mothers predict reduced ventral striatum activation in adolescent female offspring with and without depression

    Science.gov (United States)

    Prior research has identified reduced reward-related brain activation as a promising endophenotype for the early identification of adolescents with major depressive disorder. However, it is unclear whether reduced reward-related brain activation constitutes a true vulnerability for major depressive ...

  7. Predicting acceptance and popularity in early adolescence as a function of hearing status, gender, and educational setting

    NARCIS (Netherlands)

    Wolters, N.; Knoors, H.E.T.; Cillessen, A.H.N.; Verhoeven, L.T.W.

    2011-01-01

    This study examined associations of communicative skills, social behavior, and personality with acceptance and popularity as a function of hearing status, gender, and educational setting. Participants were 87 deaf and 672 hearing early adolescents of 52 6th grade classrooms in mainstream and special

  8. Interpersonal Sensitivity, Romantic Stress, and the Prediction of Depression: A Study of Inner-City, Minority Adolescent Girls

    Science.gov (United States)

    Rizzo, Christie J.; Daley, Shannon E.; Gunderson, Brent H.

    2006-01-01

    The role of interpersonal sensitivity in the relation between romantic stress and depression was examined in 55 adolescent girls from an inner-city high school. Depression, interpersonal sensitivity, and chronic and episodic romantic stress were measured at two time points, 6 months apart. Interpersonal sensitivity was found to moderate the…

  9. Childhood Internalizing and Externalizing Problems Predict the Onset of Clinical Panic Attacks over Adolescence: The TRAILS Study

    NARCIS (Netherlands)

    C.M. Mathyssek (Christina); T.M. Olino (Thomas); F.C. Verhulst (Frank); F.V.A. van Oort (Floor)

    2012-01-01

    textabstractBackground: Panic attacks are a source of individual suffering and are an independent risk factor for later psychopathology. However, much less is known about risk factors for the development of panic attacks, particularly during adolescence when the incidence of panic attacks increases

  10. Predicting Changes in Physical Activity among Adolescents: The Role of Self-Efficacy, Intention, Action Planning and Coping Planning

    Science.gov (United States)

    Araujo-Soares, Vera; McIntyre, Teresa; Sniehotta, Falko F.

    2009-01-01

    This paper aims to test the direct predictors of the theory of planned behaviour (TPB), action planning and coping planning as predictors of changes in physical activity (PA) in 157 adolescents (mean age: 12). TPB measures, the Action Planning and Coping Planning Scales (APCPS) and the International Physical Activity Questionnaires were measured…

  11. Insecure Attachment, Dysfunctional Attitudes, and Low Self-Esteem Predicting Prospective Symptoms of Depression and Anxiety during Adolescence

    Science.gov (United States)

    Lee, Adabel; Hankin, Benjamin L.

    2009-01-01

    This study extends the existing adult literature on insecure attachment as a predictor of depression and anxiety by examining these pathways in a sample of adolescents. In addition, dysfunctional attitudes and low self-esteem were tested as mediators of the association between insecure attachment and symptoms of depression and anxiety. Youth (N =…

  12. Psychosocial Stress Predicts Future Symptom Severities in Children and Adolescents with Tourette Syndrome and/or Obsessive-Compulsive Disorder

    Science.gov (United States)

    Lin, Haiqun; Katsovich, Liliya; Ghebremichael, Musie; Findley, Diane B.; Grantz, Heidi; Lombroso, Paul J.; King, Robert A.; Zhang, Heping; Leckman, James F.

    2007-01-01

    Background: The goals of this prospective longitudinal study were to monitor levels of psychosocial stress in children and adolescents with Tourette syndrome (TS) and/or obsessive-compulsive disorder (OCD) compared to healthy control subjects and to examine the relationship between measures of psychosocial stress and fluctuations in tic,…

  13. Predicting Transitions in Low and High Levels of Risk Behavior from Early to Middle Adolescence : The TRAILS Study

    NARCIS (Netherlands)

    Monshouwer, K.; Harakeh, Z.; Lugtig, P.; Huizink, A.; Creemers, H. E.; Reijneveld, S. A.; De Winter, A. F.; Van Oort, F.; Ormel, J.; Vollebergh, W. A. M.

    2012-01-01

    The present study examined the joint development of substance use and externalizing problems in early and middle adolescence. First, it was tested whether the relevant groups found in previous studies i.e., those with an early onset, a late onset, and no onset or low levels of risk behavior could be

  14. Decrease in Television Viewing Predicts Lower Body Mass Index at 1-Year Follow-Up in Adolescents, but Not Adults

    Science.gov (United States)

    French, Simone A.; Mitchell, Nathan R.; Hannan, Peter J.

    2012-01-01

    Objective: To examine associations between television viewing, sugar-sweetened beverage consumption, eating out, physical activity, and body weight change over 1 year. Design: Secondary data analysis from randomized intervention trial. Setting: Households in the community. Participants: Adults (n = 153) and adolescents (n = 72) from the same…

  15. Ethnic Identity Trajectories among Mexican-Origin Girls during Early and Middle Adolescence: Predicting Future Psychosocial Adjustment

    Science.gov (United States)

    Gonzales-Backen, Melinda A.; Bámaca-Colbert, Mayra Y.; Allen, Kimberly

    2016-01-01

    We examined trajectories of ethnic identity exploration, resolution, and affirmation and their associations with depressive symptoms and self-esteem 3.5 years later among early and middle adolescent Mexican-origin girls (N = 338). Findings indicated that exploration, resolution, and affirmation increased over time for both cohorts. Among early…

  16. Sorting Test, Tower Test, and BRIEF-SR do not predict school performance of healthy adolescents in preuniversity education

    NARCIS (Netherlands)

    Boschloo, Annemarie; Krabbendam, Lydia; Aben, Aukje; De Groot, Renate; Jolles, Jelle

    2016-01-01

    Executive functions (EF) such as self-monitoring, planning, and organizing are known to develop through childhood and adolescence. They are of potential importance for learning and school performance. Earlier research into the relation between EF and school performance did not provide clear results

  17. Predicting Acceptance and Popularity in Early Adolescence as a Function of Hearing Status, Gender, and Educational Setting

    Science.gov (United States)

    Wolters, Nina; Knoors, Harry E. T.; Cillessen, Antonius H. N.; Verhoeven, Ludo

    2011-01-01

    This study examined associations of communicative skills, social behavior, and personality with acceptance and popularity as a function of hearing status, gender, and educational setting. Participants were 87 deaf and 672 hearing early adolescents of 52 6th grade classrooms in mainstream and special education. Acceptance varied as a function of…

  18. Measuring Peer Pressure, Popularity, and Conformity in Adolescent Boys and Girls: Predicting School Performance, Sexual Attitudes, and Substance Abuse.

    Science.gov (United States)

    Santor, Darcy A.; Messervey, Deanna; Kusumakar, Vivek

    2000-01-01

    Developed and validated short measures of peer pressure, peer conformity, and popularity with 148 adolescent Canadian boys and girls in grades 11 to 13. Results show all constructed measures to be internally consistent. Peer pressure and peer conformity were stronger predictors of risk behavior than measures assessing popularity, general…

  19. How well can adolescents really judge risk? Simple, self reported risk factors out-predict teens' self estimates of personal risk

    Directory of Open Access Journals (Sweden)

    Alexander Persoskie

    2013-01-01

    Full Text Available Recent investigations of adolescents' beliefs about risk have led to surprisingly optimistic conclusions: Teens' self estimates of their likelihood of experiencing various life events not only correlate sensibly with relevant risk factors (Fischhoff et al., 2000, but they also significantly predict later experiencing the events (Bruine de Bruin et al., 2007. Using the same dataset examined in previous investigations, the present study extended these analyses by comparing the predictive value of self estimates of risk to that of traditional risk factors for each outcome. The analyses focused on the prediction of pregnancy, criminal arrest, and school enrollment. Three findings emerged. First, traditional risk factor information tended to out-predict self assessments of risk, even when the risk factors included crude, potentially unreliable measures (e.g., a simple tally of self-reported criminal history and when the risk factors were aggregated in a nonoptimal way (i.e., unit weighting. Second, despite the previously reported correlations between self estimates and outcomes, perceived invulnerability was a problem among the youth: Over half of the teens who became pregnant, half of those who were not enrolled in school, and nearly a third of those who were arrested had, one year earlier, indicated a 0% chance of experiencing these outcomes. Finally, adding self estimates of risk to the other risk factor information produced only small gains in predictive accuracy. These analyses point to the need for greater education about the situations and behaviors that lead to negative outcomes.

  20. Insecure Attachment, Dysfunctional Attitudes, and Low Self-Esteem Predicting Prospective Symptoms of Depression and Anxiety During Adolescence

    OpenAIRE

    Lee, Adabel; Hankin, Benjamin L.

    2009-01-01

    This study extends the existing adult literature on insecure attachment as a predictor of depression and anxiety by examining these pathways in a sample of adolescents. In addition, dysfunctional attitudes and low self-esteem were tested as mediators of the association between insecure attachment and symptoms of depression and anxiety. Youth (N =350; 6th–10th graders) completed self-report measures of attachment, dysfunctional attitudes, self-esteem, and symptoms of depression and anxiety in ...

  1. Sorting Test, Tower Test, and BRIEF-SR do not predict school performance of healthy adolescents in preuniversity education

    OpenAIRE

    Annemarie eBoschloo; Lydia eKrabbendam; Aukje eAben; Renate Helena Maria De Groot; Jelle eJolles

    2014-01-01

    Executive functions (EF) such as self-monitoring, planning and organizing are known to develop through childhood and adolescence. They are of potential importance for learning and school performance. Earlier research into the relation between executive functions and school performance did not provide clear results possibly because confounding factors such as educational track, boy-girl differences and parental education were not taken into account. The present study therefore investigated the...

  2. Development of predictive genetic tests for improving the safety of new medicines : the utilization of routinely collected electronic health records

    NARCIS (Netherlands)

    Wing, Kevin; Douglas, Ian; Bhaskaran, Krishnan; Klungel, Olaf H; Reynolds, Robert F; Pirmohamed, Munir; Smeeth, Liam; van Staa, Tjeerd P

    2014-01-01

    Serious adverse drug reactions are an important cause of hospitalization and can result in the withdrawal of licensed drugs. Genetic variation has been shown to influence adverse drug reaction susceptibility, and predictive genetic tests have been developed for a limited number of adverse drug react

  3. Adolescent development

    Science.gov (United States)

    Development - adolescent; Growth and development - adolescent ... rights and privileges. Establish and maintain satisfying relationships. Adolescents will learn to share intimacy without feeling worried ...

  4. A 7 year follow-up of children and adolescents with obsessive-compulsive disorder: an analysis of predictive factors in a clinical prospective study

    Directory of Open Access Journals (Sweden)

    Judith Becker Nissen

    2014-09-01

    Full Text Available Background and Objectives: Obsessive compulsive disorder (OCD is a frequent psychiatric disorder. Despite its significant influence on personal development, little is known about its long-term course in children and adolescents. The aim was to follow children and adolescents with OCD for 7 years and to compare patients gaining remission with patients experiencing symptoms. Methods: The study was a prospective follow-up study in which the patients were interviewed 7 years after their initial contact with the healthcare system. The patients had been described at baseline. Results: Among the 95 participants, 53 participants described symptoms at follow-up and 44 participants described remission. More patients with persistent symptoms described an anxious personality trait. The schizoid/compulsive personality traits were represented at a higher rate in the group with persistent symptoms than in the group with remission symptoms. Important predictive factors included predisposition to OCD, the occurrence of comorbid disorders and older referral age. The occurrence of magic obsessions and repetitive compulsions increased the risk of OC symptoms at follow-up. The group “late responders” differed from the non-responder group by predisposition to depression. Conclusions: The present clinical study is one of the longest follow-up studies conducted in children and adolescents with OCD. In addition to confirming several previous findings, the study added new knowledge about the importance of phenotypic presentation, personality traits and quality of life. Furthermore, the late responder group has been described in relation to the remission group and to the group with persistent symptoms.

  5. The dopamine receptor D4 gene and familial loading interact with perceived parenting in predicting externalizing behavior problems in early adolescence: the TRacking Adolescents' Individual Lives Survey (TRAILS)

    NARCIS (Netherlands)

    Marsman, R.; Oldehinkel, A.J.; Ormel, J.; Buitelaar, J.K.

    2013-01-01

    Although externalizing behavior problems show in general a high stability over time, the course of externalizing behavior problems may vary from individual to individual. Our main goal was to investigate the predictive role of parenting on externalizing behavior problems. In addition, we investigate

  6. The dopamine receptor D4 gene and familial loading interact with perceived parenting in predicting externalizing behavior problems in early adolescence : The TRacking Adolescents' Individual Lives Survey (TRAILS)

    NARCIS (Netherlands)

    Marsman, Rianne; Oldehinkel, Albertine J.; Ormel, Johan; Buitelaar, Jan K.

    2013-01-01

    Although externalizing behavior problems show in general a high stability over time, the course of externalizing behavior problems may vary from individual to individual. Our main goal was to investigate the predictive role of parenting on externalizing behavior problems. In addition, we investigate

  7. Marfan syndrome in children and adolescents: predictive and prognostic value of aortic root growth for screening for aortic complications

    OpenAIRE

    Groenink, M; Rozendaal, L; Naeff, M.S.J.; Hennekam, R.C.M.; Hart, A.A.M.; Wall; Mulder, B.J.M.

    1998-01-01

    Objective—To assess and measure the diagnostic and prognostic value of individual aortic root growth in children and adolescents with Marfan syndrome.
Design—From 1983 to 1996, 250 children were screened for Marfan syndrome. Serial echocardiographic aortic root measurements of 123 children (57 Marfan, 66 control) were available for evaluation of aortic root growth. Aortic root diameters were correlated with body surface area. Based on individual growth of the aortic root a discrimination form...

  8. Prediction

    CERN Document Server

    Sornette, Didier

    2010-01-01

    This chapter first presents a rather personal view of some different aspects of predictability, going in crescendo from simple linear systems to high-dimensional nonlinear systems with stochastic forcing, which exhibit emergent properties such as phase transitions and regime shifts. Then, a detailed correspondence between the phenomenology of earthquakes, financial crashes and epileptic seizures is offered. The presented statistical evidence provides the substance of a general phase diagram for understanding the many facets of the spatio-temporal organization of these systems. A key insight is to organize the evidence and mechanisms in terms of two summarizing measures: (i) amplitude of disorder or heterogeneity in the system and (ii) level of coupling or interaction strength among the system's components. On the basis of the recently identified remarkable correspondence between earthquakes and seizures, we present detailed information on a class of stochastic point processes that has been found to be particu...

  9. Extending the theory of planned behavior: the role of self and social influences in predicting adolescent regular moderate-to-vigorous physical activity.

    Science.gov (United States)

    Hamilton, Kyra; White, Katherine M

    2008-02-01

    The current study aimed to test the validity of an extended theory of planned behavior model (TPB; Ajzen, 1991), incorporating additional self and social influences, for predicting adolescent moderate-to-vigorous physical activity. Participants (N = 423) completed an initial questionnaire that assessed the standard TPB constructs of attitude, subjective norm, and perceived behavioral control, as well as past behavior, self-identity, and the additional social influence variables of group norms, family social support, friends' social support, and social provisions. One week after completion of the main questionnaire, participants completed a follow-up questionnaire that assessed self-reported physical activity during the previous week. The standard TPB variable--past behavior, self-identity, and group norms, but not social support influences--predicted intentions, with intention, past behavior, and self-identity predicting behavior. Overall, the results provide support for an extended version of the TPB incorporating self-identity and those social influences linked explicitly to membership of a behaviorally relevant reference group. PMID:18369243

  10. Predicting condom use in adolescents: a test of three socio-cognitive models using a structural equation modeling approach

    OpenAIRE

    Espada, José P.; Morales, Alexandra; Guillén-Riquelme, Alejandro; Ballester, Rafael; Orgilés, Mireia

    2016-01-01

    Background The theory of planned behavior (TPB), socio-cognitive model (SCM), and information-motivation-behavioral skills (IMB) model are effective in predicting condom use. However, the adequacy of these three theoretical models in predicting the frequency of condom use (FCU) among young people has not been compared. This cross-sectional study tested the applicability and suitability of these three models in predicting the FCU, and analyzed the relationships among the postulated constructs....

  11. Children's Knowledge about Medicines.

    Science.gov (United States)

    Almarsdottir, Anna B.; Zimmer, Catherine

    1998-01-01

    Examined knowledge about medicines and perceived benefit among 101 children, ages 7 and 10. Found that medicine knowledge was explained using age, educational environment, and degree of internal locus of control as significant predictors. The negative effect of internal locus of control predicted perceived benefit. Retention of drug advertising…

  12. Parents' School Satisfaction and Academic Socialization Predict Adolescents' Autonomous Motivation: A Mixed-Method Study of Low-Income Ethnic Minority Families

    Science.gov (United States)

    Suizzo, Marie-Anne; Jackson, Karen Moran; Pahlke, Erin; McClain, Shannon; Marroquin, Yesenia; Blondeau, Lauren A.; Hong, KyongJoo

    2016-01-01

    In this mixed-methods study, we used an explanatory sequential design to investigate the processes through which parental involvement influences adolescents' achievement motivation. One hundred twenty low-income urban parents and their sixth-grade adolescents completed questionnaires, and a subsample of 11 mothers and 11 adolescents were…

  13. Reciprocal Effects between Parental Solicitation, Parental Control, Adolescent Disclosure, and Adolescent Delinquency

    Science.gov (United States)

    Keijsers, Loes; Branje, Susan J. T.; VanderValk, Inge E.; Meeus, Wim

    2010-01-01

    This two-wave multi-informant study examined the bidirectional associations of parental control and solicitation with adolescent disclosure and delinquency. Participants were 289 adolescents (150 females and 139 males, modal age 14) and both parents. Parental solicitation and control did not predict adolescent delinquency, but adolescents'…

  14. Pharmacogenetic efficacy of perindopril in children and adolescents with type 1 diabetes mellitus in prediction of diabetic nephropathy

    Directory of Open Access Journals (Sweden)

    Gulnara Rakhimova

    2013-04-01

    Full Text Available DD genotype of ACE gene is a predisposing factor for chronic kidney disease terminating nephrotic syndrome in children with type 1 diabetes mellitus, while ACE gene II genotype upon diabetic nephropathy appears to be a protective one. The work was initiated to assess efficacy of perindopril in normoalbuminuric patients with type 1 diabetes mellitus by ACE genotype in the primary intervention of diabetic nephropathy. 22 normoalbuminuric patients with type 1 diabetes mellitus aged from 12 to 70 with diabetic nephropathy duration of 10 and more years were examined to be divided into two groups by ACE polymorphism including eleven-by-eleven carriers of II genotype and DD genotype, respectively. Perindopril in low doses is recommended to treat normoalbuminuric children and adolescents for optimization of intervention and therapy of diabetic nephropathy.

  15. Exposure to media predicts use of dietary supplements and anabolic-androgenic steroids among Flemish adolescent boys.

    Science.gov (United States)

    Frison, Eline; Vandenbosch, Laura; Eggermont, Steven

    2013-10-01

    This study examined whether different types of media affect the use of dietary proteins and amino acid supplements, and intent to use anabolic-androgenic steroids. A random sample of 618 boys aged 11-18 years from eight schools in the Flemish part of Belgium completed standardized questionnaires as part of the Media and Adolescent Health Study. The survey measured exposure to sports media, appearance-focused media, fitness media, use of dietary supplements, and intent to use anabolic-androgenic steroids. Data were analyzed using logistic regressions and are presented as adjusted odds ratios (OR) and 95 % confidence intervals (CI); 8.6 % indicated to have used dietary proteins, 3.9 % indicated to have used amino acid supplements, and 11.8 % would consider using anabolic-androgenic steroids. After adjusting for fitness activity, exposure to fitness media was associated with the use of dietary proteins (OR = 7.24, CI = 2.25-23.28) and amino acid supplements (5.16, 1.21-21.92; 44.30, 8.25-238). Intent to use anabolic-androgenic steroids was associated with exposure to fitness media (2.38, 1.08-5.26; 8.07, 2.55-25.53) and appearance-focused media (6.02, 1.40-25.82; 8.94, 1.78-44.98). Sports media did not correlate with the use of dietary supplements and intent to use anabolic-androgenic steroids. Specific types of media are strong predictors of the use of supplements in adolescent boys. This provides an opportunity for intervention and prevention through the selection of fitness media as a communication channel. Health practitioners should also be aware that the contemporary body culture exerts pressure not only on girls but also on boys.

  16. Family medicine, ‘La Herencia’ and breast cancer; understanding the (dis)continuities of predictive genetics in Cuba

    Science.gov (United States)

    Gibbon, Sahra

    2011-01-01

    Building on social science research examining the relationship between genetic knowledge, identity and the family this paper takes the cultural context of Cuba as a site for critical ethnographic engagement. The paper makes use of research working with a range of Cuban publics and genetic professionals as part of a collaborative research project exploring the social and cultural context of health beliefs about breast cancer. It illuminates the contrasting ways in which genomic knowledge linked to an increased risk of breast cancer is perceived, communicated, and acted upon. It is argued that the particular meaning and significance of genetic risk linked to breast cancer in this context must be examined in relation to long standing institutional practices relating to public health care provision. The focus on ‘the family’ in the provision of Cuban health provides a particularly viable foundation for the expansion of what is described as ‘community genetics’, including the collation of family history details for common complex diseases such as breast cancer. Nevertheless specific public perceptions of risk related to breast cancer and the difficulties of discussing a diagnosis of cancer openly in the family point to the very specific challenges for the translation and application of predictive interventions in Cuba. In summary the dynamic interrelationship between public health, perceptions of risk or health beliefs about the causes of the disease and attitudes towards cancer diagnosis within the family point to both continuities and discontinuities in the way that genomic interventions linked to breast cancer are unfolding as part of a dynamic yet still ostensibly socialist project of health care in Cuba. PMID:21239101

  17. Family medicine, 'La Herencia' and breast cancer; understanding the (dis)continuities of predictive genetics in Cuba.

    Science.gov (United States)

    Gibbon, Sahra

    2011-06-01

    Building on social science research examining the relationship between genetic knowledge, identity and the family this paper takes the cultural context of Cuba as a site for critical ethnographic engagement. The paper makes use of research working with a range of Cuban public and genetic professionals as part of a collaborative research project exploring the social and cultural context of health beliefs about breast cancer. It illuminates the contrasting ways in which genomic knowledge linked to an increased risk of breast cancer is perceived, communicated, and acted upon. It is argued that the particular meaning and significance of genetic risk linked to breast cancer in this context must be examined in relation to long standing institutional practices relating to public health care provision. The focus on 'the family' in the provision of Cuban health provides a particularly viable foundation for the expansion of what is described as 'community genetics', including the collation of family history details for common complex diseases such as breast cancer. Nevertheless specific public perceptions of risk related to breast cancer and the difficulties of discussing a diagnosis of cancer openly in the family point to the very specific challenges for the translation and application of predictive interventions in Cuba. In summary the dynamic interrelationship between public health, perceptions of risk or health beliefs about the causes of the disease and attitudes towards cancer diagnosis within the family point to both continuities and discontinuities in the way that genomic interventions linked to breast cancer are unfolding as part of a dynamic yet still ostensibly socialist project of health care in Cuba.

  18. Predictors of smoking among Swedish adolescents

    OpenAIRE

    Joffer, Junia; Burell, Gunilla; Bergström, Erik; Stenlund, Hans; Sjörs, Linda; Jerdén, Lars

    2014-01-01

    BACKGROUND: Smoking most often starts in adolescence, implying that understanding of predicting factors for smoking initiation during this time period is essential for successful smoking prevention. The aim of this study was to examine predicting factors in early adolescence for smoking in late adolescence. METHODS: Longitudinal cohort study, involving 649 Swedish adolescents from lower secondary school (12-13 years old) to upper secondary school (17-18 years old). Tobacco habits, behavioural...

  19. Aerospace Medicine

    Science.gov (United States)

    Michaud, Vince

    2015-01-01

    NASA Aerospace Medicine overview - Aerospace Medicine is that specialty area of medicine concerned with the determination and maintenance of the health, safety, and performance of those who fly in the air or in space.

  20. Identification of a Predictive Biomarker for the Beneficial Effect of Keishibukuryogan, a Kampo (Japanese Traditional Medicine, on Patients with Climacteric Syndrome

    Directory of Open Access Journals (Sweden)

    Takao Namiki

    2014-01-01

    Full Text Available Keishibukuryogan (KBG; Guizhi-Fuling-Wan in Chinese is one of the Kampo (Japanese traditional medicines used to treat patients with climacteric syndrome. KBG can be used by patients who cannot undergo hormone replacement therapy due to a history of breast cancer. We evaluated whether cytosine-adenine (CA repeat polymorphism of the estrogen receptor β gene can be a predictor of the beneficial effect of KBG on climacteric syndrome. We also investigated the relationship between CA repeat polymorphism, the patients’ profiles, and the therapeutic effect. We found that CA was an SS, SL, or LL genotype according to the number of repeats. We studied 39 consecutive patients with climacteric disorders who took KBG for 12 weeks. The diagnosis of climacteric disorders was made on the basis of the Kupperman index. KBG significantly improved the patients’ climacteric symptoms (i.e., vasomotor symptoms in the patients with the LL genotype and melancholia in the patients with the SL genotype. No relationship between the patients’ profiles and CA repeat polymorphism was recognized. CA repeat polymorphism could thus be a potential biomarker to predict the efficacy of KBG in climacteric syndrome, and its use will help to reduce the cost of treating this syndrome by focusing the administration of KBG on those most likely to benefit from it.

  1. A meta-analytic review of depression prevention programs for children and adolescents: factors that predict magnitude of intervention effects.

    Science.gov (United States)

    Stice, Eric; Shaw, Heather; Bohon, Cara; Marti, C Nathan; Rohde, Paul

    2009-06-01

    In this meta-analytic review, the authors summarized the effects of depression prevention programs for youth as well as investigated participant, intervention, provider, and research design features associated with larger effects. They identified 47 trials that evaluated 32 prevention programs, producing 60 intervention effect sizes. The average effect for depressive symptoms from pre-to-posttreatment (r = .15) and pretreatment to-follow-up (r = .11) were small, but 13 (41%) prevention programs produced significant reductions in depressive symptoms and 4 (13%) produced significant reductions in risk for future depressive disorder onset relative to control groups. Larger effects emerged for programs targeting high-risk individuals, samples with more females, samples with older adolescents, programs with a shorter duration and with homework assignments, and programs delivered by professional interventionists. Intervention content (e.g., a focus on problem-solving training or reducing negative cognitions) and design features (e.g., use of random assignment and structured interviews) were unrelated to effect sizes. Results suggest that depression prevention efforts produce a higher yield if they incorporate factors associated with larger intervention effects (e.g., selective programs with a shorter duration that include homework).

  2. Objectively measured physical activity predicts hip and spine bone mineral content in children and adolescents ages 5 - 15 years: Iowa Bone Development Study

    Directory of Open Access Journals (Sweden)

    Kathleen F Janz

    2014-07-01

    Full Text Available This study examined the association between physical activity (PA and bone mineral content (BMC; g from middle childhood to middle adolescence and compared the impact of vigorous-intensity PA (VPA over moderate- to vigorous-intensity PA (MVPA. Participants from the Iowa Bone Development Study were examined at ages 5, 8, 11, 13, and 15 yr (n=369, 449, 452, 410, 307, respectively. MVPA and VPA (min/day were measured using ActiGraph accelerometers. Anthropometry was used to measure body size and somatic maturity. Spine BMC and hip BMC were measured via dual-energy x-ray absorptiometry. Sex-specific multi-level linear models were fit for spine BMC and hip BMC, adjusted for weight (kg, height (cm, linear age (yr, non-linear age (yr2, and maturity (pre peak height velocity vs. at/post peak height velocity. The interaction effects of PA×maturity and PA×age were tested. We also examined differences in spine BMC and hip BMC between the least (10th percentile and most (90th percentile active participants at each examination period. Results indicated that PA added to prediction of BMC throughout the 10-year follow-up, except MVPA did not predict spine BMC in females. Maturity and age did not modify the PA effect for males nor females. At age 5, the males at the 90th percentile for VPA had 8.5% more hip BMC than males in the 10th percentile for VPA. At age 15, this difference was 2.0%. Females at age 5 in the 90th percentile for VPA had 6.1% more hip BMC than those in the 10th percentile for VPA. The age 15 difference was 1.8%. VPA was associated with BMC at weight-bearing skeletal sites from childhood to adolescence, and the effect was not modified by maturity or age. Our findings indicate the importance of early and sustained interventions that focus on VPA. Approaches focused on MVPA may be inadequate for optimal bone health, particularly for females.

  3. Predicting performance using background characteristics of international medical graduates in an inner-city university-affiliated Internal Medicine residency training program

    Directory of Open Access Journals (Sweden)

    Akhuetie Jane

    2009-07-01

    Full Text Available Abstract Background IMGs constitute about a third of the United States (US internal medicine graduates. US residency training programs face challenges in selection of IMGs with varied background features. However data on this topic is limited. We analyzed whether any pre-selection characteristics of IMG residents in our internal medicine program are associated with selected outcomes, namely competency based evaluation, examination performance and success in acquiring fellowship positions after graduation. Methods We conducted a retrospective study of 51 IMGs at our ACGME accredited teaching institution between 2004 and 2007. Background resident features namely age, gender, self-reported ethnicity, time between medical school graduation to residency (pre-hire time, USMLE step I & II clinical skills scores, pre-GME clinical experience, US externship and interest in pursuing fellowship after graduation expressed in their personal statements were noted. Data on competency-based evaluations, in-service exam scores, research presentation and publications, fellowship pursuance were collected. There were no fellowships offered in our hospital in this study period. Background features were compared between resident groups according to following outcomes: (a annual aggregate graduate PGY-level specific competency-based evaluation (CBE score above versus below the median score within our program (scoring scale of 1 – 10, (b US graduate PGY-level specific resident in-training exam (ITE score higher versus lower than the median score, and (c those who succeeded to secure a fellowship within the study period. Using appropriate statistical tests & adjusted regression analysis, odds ratio with 95% confidence intervals were calculated. Results 94% of the study sample were IMGs; median age was 35 years (Inter-Quartile range 25th – 75th percentile (IQR: 33–37 years; 43% women and 59% were Asian physicians. The median pre-hire time was 5 years (IQR: 4–7

  4. Adolescent Aggression and Social Cognition in the Context of Personality: Impulsivity as a Moderator of Predictions from Social Information Processing

    OpenAIRE

    Fite, Jennifer E.; Goodnight, Jackson A.; Bates, John E.; Dodge, Kenneth A.; Pettit, Gregory S.

    2008-01-01

    This study asked how individual differences in social cognition and personality interact in predicting later aggressive behavior. It was hypothesized that the relationship between immediate response evaluations in social information processing (SIP) and later aggressive behavior would be moderated by impulsivity. In particular, the immediate positive evaluations of aggressive responses would be more strongly related to later aggressive behavior for high-impulsive than for low-impulsive indivi...

  5. Predicting borderline personality disorder symptoms in adolescents from childhood physical and relational aggression, depression, and attention-deficit/hyperactivity disorder.

    Science.gov (United States)

    Vaillancourt, Tracy; Brittain, Heather L; McDougall, Patricia; Krygsman, Amanda; Boylan, Khrista; Duku, Eric; Hymel, Shelley

    2014-08-01

    Developmental cascade models linking childhood physical and relational aggression with symptoms of depression and attention-deficit/hyperactivity disorder (ADHD; assessed at ages 10, 11, 12, 13, and 14) to borderline personality disorder (BPD) features (assessed at age 14) were examined in a community sample of 484 youth. Results indicated that, when controlling for within-time covariance and across-time stability in the examination of cross-lagged relations among study variables, BPD features at age 14 were predicted by childhood relational aggression and symptoms of depression for boys, and physical and relational aggression, symptoms of depression, and symptoms of ADHD for girls. Moreover, for boys BPD features were predicted from age 10 ADHD through age 12 depression, whereas for girls the pathway to elevated BPD features at age 14 was from depression at age 10 through physical aggression symptoms at age 12. Controlling for earlier associations among variables, we found that for girls the strongest predictor of BPD features at age 14 was physical aggression, whereas for boys all the risk indicators shared a similar predictive impact. This study adds to the growing literature showing that physical and relational aggression ought to be considered when examining early precursors of BPD features.

  6. Maturation of the adolescent brain

    OpenAIRE

    Arain M; Haque M; Johal L; Mathur P; Nel W; Rais A; Sandhu R; Sharma S

    2013-01-01

    Mariam Arain, Maliha Haque, Lina Johal, Puja Mathur, Wynand Nel, Afsha Rais, Ranbir Sandhu, Sushil Sharma Saint James School of Medicine, Kralendijk, Bonaire, The Netherlands Abstract: Adolescence is the developmental epoch during which children become adults – intellectually, physically, hormonally, and socially. Adolescence is a tumultuous time, full of changes and transformations. The pubertal transition to adulthood involves both gonadal and behavioral maturation. Magnetic resonance...

  7. A longitudinal examination of the Adaptation to Poverty-Related Stress Model: predicting child and adolescent adjustment over time.

    Science.gov (United States)

    Wadsworth, Martha E; Rindlaub, Laura; Hurwich-Reiss, Eliana; Rienks, Shauna; Bianco, Hannah; Markman, Howard J

    2013-01-01

    This study tests key tenets of the Adaptation to Poverty-related Stress Model. This model (Wadsworth, Raviv, Santiago, & Etter, 2011 ) builds on Conger and Elder's family stress model by proposing that primary control coping and secondary control coping can help reduce the negative effects of economic strain on parental behaviors central to the family stress model, namely, parental depressive symptoms and parent-child interactions, which together can decrease child internalizing and externalizing problems. Two hundred seventy-five co-parenting couples with children between the ages of 1 and 18 participated in an evaluation of a brief family strengthening intervention, aimed at preventing economic strain's negative cascade of influence on parents, and ultimately their children. The longitudinal path model, analyzed at the couple dyad level with mothers and fathers nested within couple, showed very good fit, and was not moderated by child gender or ethnicity. Analyses revealed direct positive effects of primary control coping and secondary control coping on mothers' and fathers' depressive symptoms. Decreased economic strain predicted more positive father-child interactions, whereas increased secondary control coping predicted less negative mother-child interactions. Positive parent-child interactions, along with decreased parent depression and economic strain, predicted child internalizing and externalizing over the course of 18 months. Multiple-group models analyzed separately by parent gender revealed, however, that child age moderated father effects. Findings provide support for the adaptation to poverty-related stress model and suggest that prevention and clinical interventions for families affected by poverty-related stress may be strengthened by including modules that address economic strain and efficacious strategies for coping with strain. PMID:23323863

  8. Poor peer relations predict parent- and self-reported behavioral and emotional problems of adolescents with gender dysphoria: a cross-national, cross-clinic comparative analysis.

    Science.gov (United States)

    de Vries, Annelou L C; Steensma, Thomas D; Cohen-Kettenis, Peggy T; VanderLaan, Doug P; Zucker, Kenneth J

    2016-06-01

    This study is the third in a series to examine behavioral and emotional problems in children and adolescents with gender dysphoria in a comparative analysis between two clinics in Toronto, Ontario, Canada and Amsterdam, the Netherlands. In the present study, we report Child Behavior Checklist (CBCL) and Youth Self-Report (YSR) data on adolescents assessed in the Toronto clinic (n = 177) and the Amsterdam clinic (n = 139). On the CBCL and the YSR, we found that the percentage of adolescents with clinical range behavioral and emotional problems was higher when compared to the non-referred standardization samples but similar to the referred adolescents. On both the CBCL and the YSR, the Toronto adolescents had a significantly higher Total Problem score than the Amsterdam adolescents. Like our earlier studies of CBCL data of children and Teacher's Report Form data of children and adolescents, a measure of poor peer relations was the strongest predictor of CBCL and YSR behavioral and emotional problems in gender dysphoric adolescents. PMID:26373289

  9. A Prospective Study of Adolescent Pregnancy.

    Science.gov (United States)

    Hockaday, Cathy; Crase, Sedahlia Jasper; Shelley, Mack C., II; Stockdale, Dahlia F.

    2000-01-01

    Examines prospectively the characteristics contributing to adolescent pregnancy in a pregnant and comparison group of adolescents. Adolescent pregnancy in Blacks was predicted by approval of delaying a family and pursuing a career, aspirations of working, and lower educational expectations. Higher educational wishes, lower educational…

  10. Investigation of Aggravating Psychosocial Factors on Health and Predictability of Smoking and Alcohol Use in Post Adolescent Students.

    Science.gov (United States)

    Barmpagianni, Effrosyni; Travlos, Antonios; Kalokairinou, Athina; Sachlas, Athanasios; Zyga, Sofia

    2013-04-18

    Purpose of this study is to explore those factors which affect the health of students in postadolescent age, focusing on smoking and alcohol use, especially in regard to ways of predicting adoption of this behavior and its frequency to detect future users of tobacco and alcohol use but also high-risk groups, i.e. those people who are led to abuses. On the basis of the research part is the Theory of Planned Behaviour, the axes of which are to be investigated. Specifically, the factors evaluated, except for population parameters, behavioral attitudes, i.e. attitudes towards the behavior of tobacco use and alcohol regulations subjective perceptions and perceptions of control, perceived behavioral control and self-efficacy. Intention is explored to continue or start using tobacco and alcohol in the future and evaluate the behavior. The sample consisted of 138 students of postadolescent age, 18-25 years of both sexes, all of the University of Peloponnese and the Technological Educational Institute of Kalamata, Department of Sparta, Greece. The results of a series of statistical analysis, via SPSS 21.0 statistical program revealed the predictive power of perceived behavioral control and subjective norms to the intention of interpreting 64% of the variance of the latter, of the attitudes toward alcohol in relation to intention that interpret 69% of the variance, of the normative beliefs toward smoking with 69% range of interpretation to the dependent variable, of the perceived behavioral control of smoking with 72% and of the attitudes toward smoking with 77% of interpretation. The results demonstrate the significance and application in universities and technological educational institutes appropriate primary preventive interventions for students nonusers of tobacco and alcohol and appropriate programs of secondary and tertiary prevention in heavy users of tobacco and alcohol use and high-risk individual. PMID:26973900

  11. Investigation of aggravating psychosocial factors on health and predictability of smoking and alcohol use in post adolescent students

    Directory of Open Access Journals (Sweden)

    Effrosyni Barmpagianni

    2013-04-01

    Full Text Available Purpose of this study is to explore those factors which affect the health of students in postadolescent age, focusing on smoking and alcohol use, especially in regard to ways of predicting adoption of this behavior and its frequency to detect future users of tobacco and alcohol use but also high-risk groups, i.e. those people who are led to abuses. On the basis of the research part is the Theory of Planned Behaviour, the axes of which are to be investigated. Specifically, the factors evaluated, except for population parameters, behavioral attitudes, i.e. attitudes towards the behavior of tobacco use and alcohol regulations subjective perceptions and perceptions of control, perceived behavioral control and self-efficacy. Intention is explored to continue or start using tobacco and alcohol in the future and evaluate the behavior. The sample consisted of 138 students of postadolescent age, 18-25 years of both sexes, all of the University of Peloponnese and the Technological Educational Institute of Kalamata, Department of Sparta, Greece. The results of a series of statistical analysis, via SPSS 21.0 statistical program revealed the predictive power of perceived behavioral control and subjective norms to the intention of interpreting 64% of the variance of the latter, of the attitudes toward alcohol in relation to intention that interpret 69% of the variance, of the normative beliefs toward smoking with 69% range of interpretation to the dependent variable, of the perceived behavioral control of smoking with 72% and of the attitudes toward smoking with 77% of interpretation. The results demonstrate the significance and application in universities and technological educational institutes appropriate primary preventive interventions for students nonusers of tobacco and alcohol and appropriate programs of secondary and tertiary prevention in heavy users of tobacco and alcohol use and high-risk individual.

  12. Self constructing in adolescence

    Directory of Open Access Journals (Sweden)

    Vranješević Jelena

    2003-01-01

    Full Text Available The aim of this study was to explore “theories” adolescents have about themselves, i.e. about the changes in the ways they construe themselves in the period of middle adolescence: how they construe changes and estimate them according to some dimensions relevant for change (appreciation of change, its importance, expectancy, timing, comprehensiveness, intensity and visibility in social surroundings. The study was explorative and it was performed on the sample of 96 adolescents aged 15-17 (middle adolescence. Instruments used for the study were: interview and Role Construct Repertory Grid, adjusted to the need of study. The results show that the adolescents’ construct system is highly monolithic and tight in regard to constructs (black and white construing, but at the same time vague and predictively unclear in regard to elements, i. e. the stated changes, meaning that adolescents are not able to construe those changes according to certain constructs. It seems that this study included the beginning of the loosening phase (creativity cycle in which the system is still tight and, therefore, protects from threat and anxiety, while the elements are not predictively (this is what Erikson calls moratorium, i.e. the process of active experimenting. Changes which are fully predictively are those which refer to adults' roles, such as: self confident, experienced, independent and has responsibilities, worries. On the hand, changes which are predictably the most clear to adolescents (and not appreciated are depression and nervousness. Adolescents face an implicative dilemma: positive implications of maturity are not enough, while negative implications, such as nervousness, depression and not trusting people are clear, predictable and negative. This dilemma can be the cause of their ambivalence towards growing-up and accepting the roles of adults.

  13. Farmácias domiciliares e sua relação com a automedicação em crianças e adolescentes Home medicine chests and their relationship with self-medication in children and adolescents

    Directory of Open Access Journals (Sweden)

    Francis S. V. Tourinho

    2008-10-01

    Full Text Available OBJETIVO: Analisar as características das farmácias domiciliares e sua relação com a automedicação em crianças e adolescentes dos municípios de Limeira e Piracicaba (SP. MÉTODOS: Estudo descritivo tipo inquérito populacional domiciliar de uma amostra aleatória simples de ambos os municípios, constituída de 705 domicílios de setores censitários selecionados por meio de amostragem por conglomerado. Critérios de inclusão: idade ≤ 18 anos; entrevista obrigatória com um dos responsáveis; inventário da farmácia domiciliar e ter consumido pelo menos um medicamento nos 15 dias prévios à data da entrevista. Segundo o uso de medicamentos, os participantes foram divididos em dois grupos de estudo: automedicação (orientação leiga e prescrição médica. Foram realizados testes de associação linear, análise descritiva das variáveis e regressão logística múltipla. RESULTADOS: Foram identificados 3.619 medicamentos (média = 5,1/domicílio; 79,6% especialidades farmacêuticas. Os principais cômodos de estoque foram dormitórios (47,5%, cozinha (29,9% e banheiros (14,6%; 76,5% em caixas de papelão e em locais de fácil alcance a 142 crianças com idade ≤ 6 anos. Considerando somente as especialidades farmacêuticas (n = 2.891, as mais freqüentes foram analgésicos/antipiréticos (26,8% e antibióticos sistêmicos (15,3%, sendo o estoque desses medicamentos significativamente mais elevado no grupo automedicação (p OBJECTIVE: To investigate the contents of home medicine chests and their relationship with self-medication in children and adolescents in the towns of Limeira and Piracicaba, SP, Brazil. METHODS: This is a descriptive population study based on a home survey of a simple random sample from both towns, comprising 705 households from census sectors selected by means of cluster sampling. Inclusion criteria: age ≤ 18 years; an obligatory interview with at least one guardian; inventory of medicines kept at home

  14. ENDOMETRIOSIS IN ADOLESCENTS-ANALYSIS OF 6 CASES

    Institute of Scientific and Technical Information of China (English)

    杨佳欣; 沈铿; 冷金花; 郎景和

    2003-01-01

    Objective.To study the characteristics, diagnosis and treatment of endometriosis in adolescent patients. Method.Six cases of adolescent endometriosis in our hospital were reviewed retrospectively. Result. Endometriosis is the most common cause of chronic pelvic pain in adolescents. There may be a natural progression of endometriosis from atypical lesions in adolescents to classic lesions in adults. Congenital abnormalities of the reproductive tract are the main reasons for the adolescent endometriosis. Conclusion. Endometriosis should be strongly suspected in adolescent girls with chronic pelvic pain,especially unresponsive to oral contraceptives and nonsteroidal anti-inflammatory drugs. The treatment involves the operations and medicines.

  15. Herbal Medicine

    Science.gov (United States)

    ... for its scent, flavor, or therapeutic properties. Herbal medicines are one type of dietary supplement. They are ... and fresh or dried plants. People use herbal medicines to try to maintain or improve their health. ...

  16. Diabetes Medicines

    Science.gov (United States)

    Diabetes means your blood glucose, or blood sugar, levels are too high. If you can't control your diabetes with wise food choices and physical activity, you may need diabetes medicines. The kind of medicine you take depends ...

  17. GENOMIC MEDICINE

    Directory of Open Access Journals (Sweden)

    Ignacio Briceño Balcázar

    2011-03-01

    Full Text Available Until the twilight of the 20th century, genetics was a branch of medicine applied to diseases of rare occurrence. The advent of the human genome sequence and the possibility of studying it at affordable costs for patients and healthcare institutions, has permitted its application in high-priority diseases like cancer, cardiovascular disease, diabetes, and Alzheimer’s, among others.There is great potential in predictive and preventive medicine, through studying polymorphic genetic variants associated to risks for different diseases. Currently, clinical laboratories offer studies of over 30,000 variants associated with susceptibilities, to which individuals can access without much difficulty because a medical prescription is not required. These exams permit conducting a specific plan of preventive medicine. For example, upon the possibility of finding a deleterious mutation in the BRCA1 and BRCA2 genes, the patient can prevent the breast cancer by mastectomy or chemoprophylaxis and in the presence of polymorphisms associated to cardiovascular risk preventive action may be undertaken through changes in life style (diet, exercise, etc..Legal aspects are also present in this new conception of medicine. For example, currently there is legislation for medications to indicate on their labels the different responses such medication can offer regarding the genetic variants of the patients, given that similar doses may provoke adverse reactions in an individual, while for another such dosage may be insufficient. This scenario would allow verifying the polymorphisms of drug response prior to administering medications like anticoagulants, hyperlipidemia treatments, or chemotherapy, among others.We must specially mention recessive diseases, produced by the presence of two alleles of a mutated gene, which are inherited from the mother, as well as the father. By studying the mutations, we may learn if a couple is at risk of bearing children with the disease

  18. Genomic Medicine

    Directory of Open Access Journals (Sweden)

    Ignacio Briceño Balcázar

    2011-04-01

    Full Text Available Until the twilight of the 20th century, genetics was a branch of medicine applied to diseases of rare occurrence.  The advent of the human genome sequence and the possibility of studying it at affordable costs for patients and healthcare institutions, has permitted its application in high-priority diseases like cancer, cardiovascular disease, diabetes, and Alzheimer’s, among others. There is great potential in predictive and preventive medicine, through studying polymorphic genetic variants associated to risks for different diseases. Currently, clinical laboratories offer studies of over 30,000 variants associated with susceptibilities, to which individuals can access without much difficulty because a medical prescription is not required. These exams permit conducting a specific plan of preventive medicine.  For example, upon the possibility of finding a deleterious mutation in the BRCA1 and BRCA2 genes, the patient can prevent the breast cancer by mastectomy or chemoprophylaxis and in the presence of polymorphisms associated to cardiovascular risk preventive action may be undertaken through changes in life style (diet, exercise, etc.. Legal aspects are also present in this new conception of medicine.  For example, currently there is legislation for medications to indicate on their labels the different responses such medication can offer regarding the genetic variants of the patients, given that similar doses may provoke adverse reactions in an individual, while for another such dosage may be insufficient. This scenario would allow verifying the polymorphisms of drug response prior to administering medications like anticoagulants, hyperlipidemia treatments, or chemotherapy, among others. We must specially mention recessive diseases, produced by the presence of two alleles of a mutated gene, which are inherited from the mother, as well as the father. By studying the mutations, we may learn if a couple is at risk of bearing children with the

  19. Medicine Women.

    Science.gov (United States)

    Beiswenger, James N., Ed.; Jeanotte, Holly, Ed.

    Described as a survival manual for Indian women in medicine, this collected work contains diverse pieces offering inspiration and practical advice for Indian women pursuing or considering careers in medicine. Introductory material includes two legends symbolizing the Medicine or Spirit Woman's role in Indian culture and an overview of Indians Into…

  20. [SPORT MEDICINE].

    Science.gov (United States)

    Constantini, Naama; Mann, Gideon

    2016-06-01

    Sports Medicine is a relatively new subject in medicine and includes a variety of medical and paramedical fields. Although sports medicine is mistakenly thought to be mainly for sports professionals/athletes, it actually encompasses the entire population, including the active and non-active healthy populations, as well as the sick. Sports medicine also engages amateur sportsmen and strives to promote physical activity and quality of life in the general population. Hence, the field involves all ages from childhood to old age, aiming to preserve and support every person at every age. Sports medicine, which started developing in the 19th century, is today a specialty, primary or secondary, in many countries, while in others it is a fellowship or under the jurisdiction of local or sports authorities. In Israel, the field exists since the 1950's and is advanced. The Sports Medicine Society founded a 3-year course of continued education in sport medicine as part of the Tel-Aviv University Faculty of Medicine. Later on, a fellowship in general Sports Medicine and in Orthopedic Sports Medicine were developed within the Israel Medical Association. A year ago, Israel formally became a member of the global "Exercise is Medicine" foundation, and under this title promotes education for health care providers on exercise prescription. The understanding of the importance of physical activity and fitness as part of a healthy lifestyle is increasing in Israel, as well as the number of amateur athletes, and the profession of sports medicine takes a big part in this process.

  1. Perceived neighborhood safety during adolescence predicts subsequent deterioration of subjective health two decades later; gender differences in a racially-diverse sample

    Directory of Open Access Journals (Sweden)

    Shervin Assari

    2015-01-01

    Conclusions: Our findings suggest that perception of unsafe neighborhoods during adolescence has negative consequences years later for the health of females. Further research is needed to replicate the findings using objective measures of health.

  2. The degree of myelosuppression during maintenance therapy of adolescents with B-lineage intermediate risk acute lymphoblastic leukemia predicts risk of relapse

    DEFF Research Database (Denmark)

    Schmiegelow, K; Donovan, Martin Heyman; Sherson, Maiken Gustafsson;

    2010-01-01

    maintenance therapy. Red blood cell MTX levels were significantly related to the dose of MTX among adolescents who stayed in remission (rS=0.38, P=0.02), which was not the case for those who developed a relapse (rS=0.15, P=0.60). Thus, compliance to maintenance therapy may influence the risk of relapse for......Drug doses, blood levels of drug metabolites and myelotoxicity during 6-mercaptopurine/methotrexate (MTX) maintenance therapy were registered for 59 adolescents (10 years) and 176 non-adolescents (<10 years) with B-cell precursor acute lymphoblastic leukemia (ALL) and a white blood cell count (WBC......) <50 × 109/l at diagnosis. Event-free survival was lower for adolescents than non-adolescents (pEFS12y:0.71 vs 0.83, P=0.04). For adolescents staying in remission, the mean WBC during maintenance therapy (mWBC) was related to age (rS=0.36, P=0.02), which became nonsignificant for those who relapsed (r...

  3. Relationship of osteopathic medical licensure examinations with undergraduate admission measures and predictive value of identifying future performance in osteopathic principles and practice/osteopathic manipulative medicine courses and rotations.

    Science.gov (United States)

    Meoli, Frederick G; Wallace, Warren S; Kaiser-Smith, Joanne; Shen, Linjun

    2002-11-01

    Two hundred sixty-five students from four classes at one school of osteopathic medicine were studied to determine the correlation between several frequently used premedical admission criteria to predict performance on the early and current versions of the osteopathic medical licensure examinations. Further analysis evaluated the predictive value of the examination of the National Board of Osteopathic Medical Examiners (NBOME) and its successor, the Comprehensive Osteopathic Medical Licensing Examination-USA (COMLEX-USA) in determining subsequent performance in the ascending levels of the examination sequence, as well as to predict performance in the courses and rotations of osteopathic principles and practice (OPP) and osteopathic manipulative medicine (OMM). This study also investigated the relationship between the early and later parts of the osteopathic medical licensure examinations. Analysis showed that of all premedical parameters, only the Medical College Aptitude Test score was positively correlated with performance on COMLEX-USA. In addition, a positive correlation was demonstrated between the performance in either Level 1 of COMLEX-USA or in the earlier form of the NBOME examination Part I and subsequent performance on the current Level 2 of COMLEX-USA or the old NBOME Part II. Finally, analysis indicated that COMLEX-USA predicted performance in OPP knowledge and skills.

  4. Women's higher health risks in the obesogenic environment: a gender nutrition approach to metabolic dimorphism with predictive, preventive, and personalised medicine

    OpenAIRE

    Shapira Niva

    2013-01-01

    Abstract Women's evolution for nurturing and fat accumulation, which historically yielded health and longevity advantages against scarcity, may now be counteracted by increasing risks in the obesogenic environment, recently shown by narrowing gender health gap. Women's differential metabolism/disease risks, i.e. in fat accumulation/distribution, exemplified during puberty/adolescence, suggest gender dimorphism with obesity outcomes. Women's higher body fat percentage than men, even with equal...

  5. Self-reported recurrent pain and medicine use behaviours among 15-year olds

    DEFF Research Database (Denmark)

    Gobina, I; Villberg, J; Villerusa, A;

    2015-01-01

    much higher for girls, the association between pain and medicine use was similarly strong for both genders. Adolescents with recurrent pain are more likely to use medicines also for non-corresponding pain, nervousness and difficulties in getting to sleep. The association between recurrent pain......-old adolescents internationally; (2) to investigate the association between recurrent pain and medicine use behaviours among boys and girls; and (3) to evaluate the consistency of these associations across countries. METHODS: The World Health Organization (WHO) collaborative international Health Behaviour...... and medicine use was consistent across countries despite large-country differences in the prevalence of recurrent pain and medicine use. CONCLUSIONS: Recurrent pain in adolescence is common cross-nationally. Adolescents with recurrent pain are more likely to use medicine in general. Recurrent pain and medicine...

  6. Complementary and Alternative Medicine (CAM) Treatments and Pediatric Psychopharmacology

    Science.gov (United States)

    Rey, Joseph M.; Walter, Garry; Soh, Nerissa

    2008-01-01

    Children and adolescents often use complementary and alternative medicine (CAM) treatments outside their indications, particularly to lose weight. Some of the herbal remedies and dietary supplements that may of relevance for psychopharmacological practice are discussed with respect to CAM treatments.

  7. Mental Health and Functional Outcomes of Maternal and Adolescent Reports of Adolescent Depressive Symptoms

    Science.gov (United States)

    Rice, Frances; Lifford, Kate J.; Thomas, Hollie V.; Thapar, Anita

    2007-01-01

    Objective: To assess the value of maternal and self-ratings of adolescent depression by investigating the extent to which these reports predicted a range of mental health and functional outcomes 4 years later. The potential influence of mother's own depressed mood on her ratings of adolescent depression and suicidal ideation on adolescent outcome…

  8. Admission Factors Predicting Family Medicine Specialty Choice: A Literature Review and Exploratory Study among Students in the Rural Medical Scholars Program

    Science.gov (United States)

    Avery, Daniel M., Jr.; Wheat, John R.; Leeper, James D.; McKnight, Jerry T.; Ballard, Brent G.; Chen, Jia

    2012-01-01

    Purpose: The Rural Medical Scholars Program (RMSP) was created to increase production of rural family physicians in Alabama. Literature review reveals reasons medical students choose careers in family medicine, and these reasons can be categorized into domains that medical schools can address through admission, curriculum, and structural…

  9. Does anti-malarial drug knowledge predict anti-malarial dispensing practice in drug outlets? A survey of medicine retailers in western Kenya

    Directory of Open Access Journals (Sweden)

    Rusk Andria

    2012-08-01

    Full Text Available Abstract Background Malaria is a major cause of morbidity and mortality in Kenya, where it is the fifth leading cause of death in both children and adults. Effectively managing malaria is dependent upon appropriate treatment. In Kenya, between 17 to 83 percent of febrile individuals first seek treatment for febrile illness over the counter from medicine retailers. Understanding medicine retailer knowledge and behaviour in treating suspected malaria and dispensing anti-malarials is crucial. Methods To investigate medicine retailer knowledge about anti-malarials and their dispensing practices, a survey was conducted of all retail drug outlets that sell anti-malarial medications and serve residents of the Webuye Health and Demographic Surveillance Site in the Bungoma East District of western Kenya. Results Most of the medicine retailers surveyed (65% were able to identify artemether-lumefantrine (AL as the Kenyan Ministry of Health recommended first-line anti-malarial therapy for uncomplicated malaria. Retailers who correctly identified this treatment were also more likely to recommend AL to adult and paediatric customers. However, the proportion of medicine retailers who recommend the correct treatment is disappointingly low. Only 48% would recommend AL to adults, and 37% would recommend it to children. It was discovered that customer demand has an influence on retailer behaviour. Retailer training and education were found to be correlated with anti-malarial drug knowledge, which in turn is correlated with dispensing practices. Medicine retailer behaviour, including patient referral practice and dispensing practices, are also correlated with knowledge of the first-line anti-malarial medication. The Kenya Ministry of Health guidelines were found to influence retailer drug stocking and dispensing behaviours. Conclusion Most medicine retailers could identify the recommended first-line treatment for uncomplicated malaria, but the percentage that could

  10. Computational intelligence in tropical medicine

    OpenAIRE

    Somsri Wiwanitkit; Viroj Wiwanitkit

    2016-01-01

    The application of computational technology for medical purpose is a very interesting topic. Knowledge content development and new technology search using computational technology becomes the newest approach in medicine. With advanced computational technology, several omics sciences are available for clarification and prediction in medicine. The computational intelligence is an important application that should be mentioned. Here, the author details and discusses on computational intelligence...

  11. The Promise of Personalized Medicine

    Science.gov (United States)

    ... Dr. Zerhouni's own experiences and hopes for the future of medicine. Klose: What motivated you to become a doctor? ... does this new need for communication affect the future of health literacy? Dr. Zerhouni : We are in a revolutionary period of medicine that I call the four Ps: predictive, personalized, ...

  12. The role of adolescent nutrition and physical activity in the prediction of verbal intelligence during early adulthood: a genetically informed analysis of twin pairs.

    Science.gov (United States)

    Jackson, Dylan B; Beaver, Kevin M

    2015-01-05

    A large body of research has revealed that nutrition and physical activity influence brain functioning at various stages of the life course. Nevertheless, very few studies have explored whether diet and exercise influence verbal intelligence as youth transition from adolescence into young adulthood. Even fewer studies have explored the link between these health behaviors and verbal intelligence while accounting for genetic and environmental factors that are shared between siblings. Employing data from the National Longitudinal Study of Adolescent Health, the current study uses a sample of same-sex twin pairs to test whether youth who engage in poorer fitness and nutritional practices are significantly more likely to exhibit reduced verbal intelligence during young adulthood. The results suggests that, independent of the effects of genetic and shared environmental factors, a number of nutritional and exercise factors during adolescence influence verbal intelligence during adulthood. Limitations are noted and suggestions for future research are outlined.

  13. The Role of Adolescent Nutrition and Physical Activity in the Prediction of Verbal Intelligence during Early Adulthood: A Genetically Informed Analysis of Twin Pairs

    Directory of Open Access Journals (Sweden)

    Dylan B. Jackson

    2015-01-01

    Full Text Available A large body of research has revealed that nutrition and physical activity influence brain functioning at various stages of the life course. Nevertheless, very few studies have explored whether diet and exercise influence verbal intelligence as youth transition from adolescence into young adulthood. Even fewer studies have explored the link between these health behaviors and verbal intelligence while accounting for genetic and environmental factors that are shared between siblings. Employing data from the National Longitudinal Study of Adolescent Health, the current study uses a sample of same-sex twin pairs to test whether youth who engage in poorer fitness and nutritional practices are significantly more likely to exhibit reduced verbal intelligence during young adulthood. The results suggests that, independent of the effects of genetic and shared environmental factors, a number of nutritional and exercise factors during adolescence influence verbal intelligence during adulthood. Limitations are noted and suggestions for future research are outlined.

  14. COPD Medicine

    Science.gov (United States)

    ... AerobiKa® Cardiology Medications Anticoagulant Medicine Anticoagulants and Drug-Food Interactions COPD Medications Bronchodilators Anti-Inflammatories Antibiotics Managing Your Medications Devices ...

  15. Equações preditivas e valores de normalidade para pressões respiratórias máximas na infância e adolescência Predictive equations and normal values for maximal respiratory pressures in childhood and adolescence

    Directory of Open Access Journals (Sweden)

    Diana Amélia de Freitas

    2011-12-01

    Full Text Available OBJETIVO: Pesquisar equações preditivas e valores de normalidade para pressões respiratórias máximas disponíveis na literatura para a faixa etária compreendida entre a infância e a adolescência. FONTES DE DADOS: Estudos publicados em inglês e em português no período entre 1980 e 2009. As bases de dados eletrônicas Lilacs e Medline foram consultadas utilizando-se as palavras-chave "capacidade respiratória máxima", "músculos respiratórios", "valores de referência", "adolescente" e "criança". SÍNTESE DOS DADOS: Foram incluídos oito artigos na revisão, totalizando 1.463 crianças e adolescentes avaliados. A faixa etária da população estudada variou de sete a 18 anos. Geralmente o indivíduo é avaliado na posição sentada e com um clipe nasal. Os esforços máximos são realizados a partir do volume residual e da capacidade pulmonar total e sustentados por um a três segundos. Valores de normalidade e equações de predição foram propostos em oito e dois estudos, respectivamente. Nestes, demonstra-se incremento nas pressões respiratórias máximas desde a infância à adolescência e a ocorrência de maiores valores de pressão expiratória máxima quando comparados à pressão inspiratória máxima em crianças e adolescentes de ambos os sexos. CONCLUSÕES: As pressões respiratórias máximas constituem um meio efetivo para avaliar a força muscular respiratória e diversos fatores contribuem para a grande variedade de equações preditivas e de valores de normalidade disponíveis. É preciso buscar um consenso para normatizar os métodos requeridos ao avaliar a força muscular respiratória em crianças e adolescentes.OBJECTIVE: To investigate predictive equations and normal values for maximal respiratory pressures available in the literature for children and adolescents. DATA SOURCES: Studies in English and Portuguese published from 1980 to 2009. Lilacs and Medline databases were consulted using the key

  16. Maturation of the adolescent brain

    Directory of Open Access Journals (Sweden)

    Arain M

    2013-04-01

    Full Text Available Mariam Arain, Maliha Haque, Lina Johal, Puja Mathur, Wynand Nel, Afsha Rais, Ranbir Sandhu, Sushil Sharma Saint James School of Medicine, Kralendijk, Bonaire, The Netherlands Abstract: Adolescence is the developmental epoch during which children become adults – intellectually, physically, hormonally, and socially. Adolescence is a tumultuous time, full of changes and transformations. The pubertal transition to adulthood involves both gonadal and behavioral maturation. Magnetic resonance imaging studies have discovered that myelinogenesis, required for proper insulation and efficient neurocybernetics, continues from childhood and the brain's region-specific neurocircuitry remains structurally and functionally vulnerable to impulsive sex, food, and sleep habits. The maturation of the adolescent brain is also influenced by heredity, environment, and sex hormones (estrogen, progesterone, and testosterone, which play a crucial role in myelination. Furthermore, glutamatergic neurotransmission predominates, whereas gamma-aminobutyric acid neurotransmission remains under construction, and this might be responsible for immature and impulsive behavior and neurobehavioral excitement during adolescent life. The adolescent population is highly vulnerable to driving under the influence of alcohol and social maladjustments due to an immature limbic system and prefrontal cortex. Synaptic plasticity and the release of neurotransmitters may also be influenced by environmental neurotoxins and drugs of abuse including cigarettes, caffeine, and alcohol during adolescence. Adolescents may become involved with offensive crimes, irresponsible behavior, unprotected sex, juvenile courts, or even prison. According to a report by the Centers for Disease Control and Prevention, the major cause of death among the teenage population is due to injury and violence related to sex and substance abuse. Prenatal neglect, cigarette smoking, and alcohol consumption may also

  17. Relationship among Translational Medicine, Evidence-Based Medicine and Precision Medicine

    Directory of Open Access Journals (Sweden)

    Xin-en HUANG

    2016-03-01

    Full Text Available Translational medicine is a new concept in international medical field. It integrates experimental research results and clinical guidance into the optimal implementation criteria for promoting the prediction, prevention and treatment of diseases. Based on people’s higher demand for medicine and health, appearance of translational medicine changes the mode of medical research.Evidence-based medicine (EBM refers to cautious and accurate application of the current best research evidence and combination of the clinician’s professional skills and abundant clinical experience to consider the patients willing and value, consequently making the best diagnostic regimens for patients. Recently, some scholars have begun to question why the patients with the same diagnosis, course of disease and pathological condition have different efficacies and prognosis after treatment with the same drug. So far, an accurate answer cannot be given based on the research data of EBM to implement translational medicine. The concept of precision medicine is accepted gradually with the development of disease management model. In this study, practice and enlightenment of translational medicine, effect of EBM on translational medicine, EBM limitations as well as emergence and development trend of precision medicine were all reviewed in order to investigate the relationship among translational medicine, EBM and precision medicine.

  18. Relationship among Translational Medicine, Evidence-Based Medicine and Precision Medicine

    Institute of Scientific and Technical Information of China (English)

    HUANG Xin-en

    2016-01-01

    Translational medicine is a new concept in international medical ifeld. It integrates experimental research results and clinical guidance into the optimal implementation criteria for promoting the prediction, prevention and treatment of diseases. Based on people’s higher demand for medicine and health, appearance of translational medicine changes the mode of medical research. Evidence-based medicine (EBM) refers to cautious and accurate application of the current best research evidence and combination of the clinician’s professional skills and abundant clinical experience to consider the patients willing and value, consequently making the best diagnostic regimens for patients. Recently, some scholars have begun to question why the patients with the same diagnosis, course of disease and pathological condition have different efifcacies and prognosis after treatment with the same drug. So far, an accurate answer cannot be given based on the research data of EBM to implement translational medicine. The concept of precision medicine is accepted gradually with the development of disease management model. In this study, practice and enlightenment of translational medicine, effect of EBM on translational medicine, EBM limitations as well as emergence and development trend of precision medicine were all reviewed in order to investigate the relationship among translational medicine, EBM and precision medicine.

  19. Ethnicity and acculturation: do they predict weight status in a longitudinal study among Asain, Hispanic, and non-Hispanic White early adolescent females?

    Science.gov (United States)

    The prevalence of overweight and obesity among adolescents has increased over the past decade. Prevalence rates are disparate among certain racial and ethnic groups. In this study, the relationship between overweight status (> 85th percentile according to the Centers for Disease Control and Prevent...

  20. Foreign Wars and Domestic Prejudice: How Media Exposure to the Israeli-Palestinian Conflict Predicts Ethnic Stereotyping by Jewish and Arab American Adolescents

    Science.gov (United States)

    Huesmann, L. Rowell; Dubow, Eric F.; Boxer, Paul; Souweidane, Violet; Ginges, Jeremy

    2012-01-01

    This study was based on the theory that adolescents view scenes of violent ethnic conflicts in the mass media through the lens of their own ethnicity, and that the resulting social-cognitive reactions influence their negative stereotypes about similar ethnic groups in their own country. We interviewed 89 Jewish and 180 Arab American high school…

  1. Predicting Treatment Success in Social Skills Training for Adolescents with Autism Spectrum Disorders: The UCLA Program for the Education and Enrichment of Relational Skills

    Science.gov (United States)

    Chang, Ya-Chih; Laugeson, Elizabeth A.; Gantman, Alexander; Ellingsen, Ruth; Frankel, Fred; Dillon, Ashley R.

    2014-01-01

    This study seeks to examine the predictors of positive social skills outcomes from the University of California, Los Angeles Program for the Education and Enrichment of Relational Skills, an evidence-based parent-assisted social skills program for high-functioning middle school and high school adolescents with autism spectrum disorders. The…

  2. Lower Psychological Well-Being and Excessive Sexual Interest Predict Symptoms of Compulsive Use of Sexually Explicit Internet Material Among Adolescent Boys

    NARCIS (Netherlands)

    Doornwaard, Suzan M.; van Den Eijnden, Regina J J M; Baams, Laura; Vanwesenbeeck, Ine; Ter Bogt, Tom F M

    2016-01-01

    Although a growing body of literature addresses the effects of young people's use of sexually explicit Internet material, research on the compulsive use of this type of online content among adolescents and its associated factors is largely lacking. This study investigated whether factors from three

  3. Predicting Developmental Change in Healthy Eating and Regular Exercise among Adolescents in China and the United States: The Role of Psychosocial and Behavioral Protection and Risk

    Science.gov (United States)

    Jessor, Richard; Turbin, Mark S.; Costa, Frances M.

    2010-01-01

    This article reports a cross-national study of developmental change in health-enhancing behavior--healthy eating and regular exercise--among adolescents in China and the United States. The application of a conceptual framework comprising psychosocial and behavioral protective and risk factors--both proximal and distal and at both the individual…

  4. A Test of the Theory of Planned Behavior to Predict Physical Activity in an Overweight/Obese Population Sample of Adolescents from Alberta, Canada

    Science.gov (United States)

    Plotnikoff, Ronald C.; Lubans, David R.; Costigan, Sarah A.; McCargar, Linda

    2013-01-01

    Purpose: To examine the utility of the theory of planned behavior (TPB) for explaining physical activity (PA) intention and behavior among a large population sample of overweight and obese adolescents (Alberta, Canada), using a web-based survey. Secondary objectives were to examine the mediating effects of the TPB constructs and moderating effects…

  5. Nuclear medicine

    International Nuclear Information System (INIS)

    The task of the Expert Committee was to review the technical development and efficacy of nuclear medicine methods and to recommend the best possible means of establishing nuclear medicine services at various levels of medical care in different countries. After reviewing the contributions which nuclear medicine can make, the various types of medical institutions and hospitals in existence, the requirements, organization and funding of nuclear medicine services, and the cost/effectiveness of nuclear medicine, a number of recommendations were made. IAEA and WHO should make information on existing methods of cost/effectiveness analysis widely available; invite governments to include a description of such analysis methods in training programmes of their health officers; assist in the acquisition of the necessary data; and encourage and eventually support actual applications of such analyses to carefully selected nuclear medicine procedures in varying medicosocial environments. They were further recommended to study possible ways of improving reliability and ease of servicing nuclear medicine equipment, and extent of possible local construction; the possibility of making available supplies of matched characterized reagents for radioimmunoassay and related techniques; and to study the advantages of establishing a network of collaborating centres on an international basis

  6. Construction of Social Reality during Early Adolescence: Can Expecting Storm and Stress Increase Real or Perceived Storm and Stress?

    Science.gov (United States)

    Buchanan, Christy M.; Hughes, Johna L.

    2009-01-01

    This study examines whether mothers' or adolescents' expectations concerning "storm and stress" behaviors at adolescence predict subsequent real or perceived adolescent behavior and attributes during the early years of adolescence. The study used a short-term longitudinal design. Participants were 6th- and 7th-grade adolescents and their mothers…

  7. Parent–Teen Interactions as Predictors of Depressive Symptoms in Adolescents with Headache

    OpenAIRE

    Lewandowski, Amy S; Palermo, Tonya M.

    2009-01-01

    This study investigated parent–adolescent conflict, family functioning, and adolescent autonomy as predictors of depressive symptoms in adolescents with primary headache. Frequent headaches during adolescence can have a negative impact on activity levels and psychological functioning. Depression is particularly prevalent in adolescents with headache but little research has examined the role of parent–teen interactions in predicting depressive symptoms. Thirty adolescents diagnosed with migrai...

  8. Adolescent health in Asia: insights from Singapore.

    Science.gov (United States)

    Oh, Jean-Yin; Rajasegaran, Kumudhini

    2016-08-01

    The introduction of adolescent medicine as a medical subspecialty in Singapore was a welcome in an evolving health care system that is unique in terms of both efficiency, in financing and the results achieved in community health outcomes. The Ministry of Health (MOH) already recognized the need to accommodate the health care concerns related to adolescent psychosocial health risk behaviors and an increased prevalence of young people living with chronic illness. The challenge for the pioneer team of physicians trained in adolescent medicine was to develop and sustain a model of care that integrated (i) core clinical services that include quality measures of care to adolescents; (ii) professional development and capacity building needing an expansive teaching agenda at every level of health education; (iii) strong inter-sectorial collaborations within hospital and community partners; and (iv) robust research and evaluation strategies that keep clinical practice relevant and evidence based. PMID:26115501

  9. Parent-Adolescent Discrepancies in Perceived Parenting Characteristics and Adolescent Developmental Outcomes in Poor Chinese Families.

    Science.gov (United States)

    Leung, Janet T Y; Shek, Daniel T L

    2014-01-01

    We examined the relationships between parent-adolescent discrepancies in perceived parenting characteristics (indexed by parental responsiveness, parental demandingness, and parental control) and adolescent developmental outcomes (indexed by achievement motivation and psychological competence) in poor families in Hong Kong. A sample of 275 intact families having at least one child aged 11-16 experiencing economic disadvantage were invited to participate in the study. Fathers and mothers completed the Parenting Style Scale and Chinese Parental Control Scale, and adolescents completed the Social-Oriented Achievement Motivation Scale and Chinese Positive Youth Development Scale in addition to paternal and maternal Parenting Style Scale and Chinese Parental Control Scale. Results indicated that parents and adolescents had different perceptions of parental responsiveness, parental demandingness, and paternal control, with adolescents generally perceived lower levels of parenting behaviors than did their parents. While father-adolescent discrepancy in perceived paternal responsiveness and mother-adolescent discrepancy in perceived maternal control negatively predicted adolescent achievement motivation, mother-adolescent discrepancy in perceptions of maternal responsiveness negatively predicted psychological competence in adolescents experiencing economic disadvantage. The present findings provided support that parent-child discrepancies in perceived parenting characteristics have negative impacts on the developmental outcomes of adolescents experiencing economic disadvantage. The present study addresses parent-child discrepancies in perceived parental behaviors as "legitimate" constructs, and explores their links with adolescent psychosocial development, which sheds light for researchers and clinical practitioners in helping the Chinese families experiencing economic disadvantage.

  10. Parent-Adolescent Discrepancies in Perceived Parenting Characteristics and Adolescent Developmental Outcomes in Poor Chinese Families.

    Science.gov (United States)

    Leung, Janet T Y; Shek, Daniel T L

    2014-01-01

    We examined the relationships between parent-adolescent discrepancies in perceived parenting characteristics (indexed by parental responsiveness, parental demandingness, and parental control) and adolescent developmental outcomes (indexed by achievement motivation and psychological competence) in poor families in Hong Kong. A sample of 275 intact families having at least one child aged 11-16 experiencing economic disadvantage were invited to participate in the study. Fathers and mothers completed the Parenting Style Scale and Chinese Parental Control Scale, and adolescents completed the Social-Oriented Achievement Motivation Scale and Chinese Positive Youth Development Scale in addition to paternal and maternal Parenting Style Scale and Chinese Parental Control Scale. Results indicated that parents and adolescents had different perceptions of parental responsiveness, parental demandingness, and paternal control, with adolescents generally perceived lower levels of parenting behaviors than did their parents. While father-adolescent discrepancy in perceived paternal responsiveness and mother-adolescent discrepancy in perceived maternal control negatively predicted adolescent achievement motivation, mother-adolescent discrepancy in perceptions of maternal responsiveness negatively predicted psychological competence in adolescents experiencing economic disadvantage. The present findings provided support that parent-child discrepancies in perceived parenting characteristics have negative impacts on the developmental outcomes of adolescents experiencing economic disadvantage. The present study addresses parent-child discrepancies in perceived parental behaviors as "legitimate" constructs, and explores their links with adolescent psychosocial development, which sheds light for researchers and clinical practitioners in helping the Chinese families experiencing economic disadvantage. PMID:24482569

  11. Predicting Intra-Individual Academic Achievement Trajectories of Adolescents Nested in Class Environment: Influence of motivation, implicit theory of intelligence, self-esteem and parenting

    OpenAIRE

    Isabelle Roskam; Frederic Nils

    2007-01-01

    In a longitudinal study conducted on 1130 adolescents (557 male and 573 female) in the 1st-6th grades from Belgian secondary schools, we tested the influence of individual factors (motivational constructs, implicit theory of intelligence and self-esteem) and environmental determinants (parenting and class environment) of academic achievement (grades in mathematics, language arts and GPA at three points in time). Using hierarchical linear models, we observed a decrease of grade over the course...

  12. Folk Medicine

    Science.gov (United States)

    ... CLPPP CAP Healthy Homes Assessment Tools Lead Health Literacy Initiative Refugee Tool Kit Resources Healthy Homes and ... As blood lead levels increase, so does lead’s effects on health. How to tell if herbal medicines ...

  13. Evidence of a Gene × Environment Interaction Between Birth Weight and Genetic Risk in the Prediction of Criminogenic Outcomes Among Adolescent Males.

    Science.gov (United States)

    Jackson, Dylan B; Beaver, Kevin M

    2016-01-01

    A number of studies have revealed that low birth weight children have a heightened risk of various maladaptive outcomes, including academic challenges and delinquent involvement. However, very little research to date has examined whether the relationship between low birth weight, poor academic performance, and delinquent peer affiliation is moderated by genetic risk. Using data from the National Longitudinal study of Adolescent Health, the present study examines whether male adolescents born at very low birth weights are significantly predisposed to poor academic performance and delinquent peer affiliation. Moreover, we test whether the effect of birth weight on these outcomes is conditioned by level of genetic risk. We find no evidence that very low birth weight males are more likely to affiliate with delinquent peers or perform poorly in school during adolescence. However, upon examining gene-environment interactions, we find that being born at a very low birth weight does significantly increase the odds of poor academic performance and delinquent peer affiliation among males who possess a higher level of genetic risk. Limitations are noted and the implications of the findings are discussed. PMID:25145687

  14. Medicinal Moves

    Institute of Scientific and Technical Information of China (English)

    2011-01-01

    Traditional Chinese medicine is becoming a new source of growth in China-Africa trade LIU Tao never expected that his traditional Chinese medicine (TCM) products would be so warmly welcomed at the annual Canton Fair last year.His surprise came after a large number of African businessmen expressed a keen interest in importing the products.That knowledge left a broad smile on his face.

  15. Adolescents' protection motivation and smoking behaviour

    OpenAIRE

    Thrul, J.; Stemmler, M.; Bühler, A; Kuntsche, E.N.

    2013-01-01

    The protection motivation theory (PMT) is a well-known theory of behaviour change. This study tested the applicability of the sub-constructs of threat and coping appraisal in predicting adolescents' smoking-related behavioural intentions and smoking behaviour longitudinally. Adolescents (N = 494) aged 11-16 years and not currently smoking at baseline participated in the study. Predictive validity of PMT constructs was tested in a path analysis model. Self-efficacy significantly predicted beha...

  16. Immunoinformatics in personalized medicine.

    Science.gov (United States)

    Gulukota, Kamalakar

    2003-01-01

    Diagnosis of human disease has been undergoing steady improvement over the past few centuries. Many ailments that were once considered a single entity have been classified into finer categories on the basis of response to therapy (e.g. type I and type II diabetes), inheritance (e.g. familial and non-familial polyposis coli), histology (e.g. small cell and adenocarcinoma of lung) and most recently transcriptional profiling (e.g. leukaemia, lymphoma). The next dimension in this finer categorization appears to be the typing of the patient rather than the disease i.e. disease X in person of type Y. The problem of personalized medicine is to devise tests which predict the type of individual, especially where the type is correlated with response to therapy. Immunology has been at the forefront of personalized medicine for quite a while, even though the term is not often used in this connection. Blood grouping and cross-matching (for blood transfusion), and anaphylaxis test (for penicillin) are just two examples. In this paper I will argue that immunological tests have an important place in the future of personalized medicine. I will describe methods we developed for personalizing vaccines based on MHC allele frequencies in human populations and methods for predicting peptide binding to class I MHC molecules. In conclusion, I will argue that immunological tests, and consequently immunoinformatics, will play a big role in making personalized medicine a reality. PMID:14712931

  17. Children's (Pediatric) Nuclear Medicine

    Medline Plus

    Full Text Available ... Resources Professions Site Index A-Z Children's (Pediatric) Nuclear Medicine Children’s (pediatric) nuclear medicine imaging uses small ... of Children's Nuclear Medicine? What is Children's (Pediatric) Nuclear Medicine? Nuclear medicine is a branch of medical ...

  18. General Nuclear Medicine

    Science.gov (United States)

    ... Resources Professions Site Index A-Z General Nuclear Medicine Nuclear medicine imaging uses small amounts of radioactive ... of General Nuclear Medicine? What is General Nuclear Medicine? Nuclear medicine is a branch of medical imaging ...

  19. Children's (Pediatric) Nuclear Medicine

    Medline Plus

    Full Text Available ... Professions Site Index A-Z Children's (Pediatric) Nuclear Medicine Children’s (pediatric) nuclear medicine imaging uses small amounts ... Children's Nuclear Medicine? What is Children's (Pediatric) Nuclear Medicine? Nuclear medicine is a branch of medical imaging ...

  20. Children's (Pediatric) Nuclear Medicine

    Science.gov (United States)

    ... Professions Site Index A-Z Children's (Pediatric) Nuclear Medicine Children’s (pediatric) nuclear medicine imaging uses small amounts ... Children's Nuclear Medicine? What is Children's (Pediatric) Nuclear Medicine? Nuclear medicine is a branch of medical imaging ...

  1. Adolescents' as Active Agents in the Socialization Process: Legitimacy of Parental Authority and Obligation to Obey as Predictors of Obedience

    Science.gov (United States)

    Darling, Nancy; Cumsille, Patricio; Loreto Martinez, M.

    2007-01-01

    Adolescents' agreement with parental standards and beliefs about the legitimacy of parental authority and their own obligation to obey were used to predict adolescents' obedience, controlling for parental monitoring, rules, and rule enforcement. Hierarchical linear models were used to predict both between-adolescent and within-adolescent,…

  2. Unexpected Death or Suicide by a Child or Adolescent: Improving Responses and Preparedness of Child and Adolescent Psychiatry Trainees

    OpenAIRE

    Sneha, Jadhav; Prakash, Chandra; Vinay, Saranga

    2011-01-01

    The death of a young patient is a difficult but universal experience in the field of medicine. It is less common in the field of child and adolescent psychiatry. However, when a child or adolescent patient commits suicide, a child and adolescent psychiatry trainee’s response could include shock, denial, disbelief, sadness, sleep difficulties, rumination about patient’s death, fears of litigation, social withdrawal, and a sense of failure. Trainees generally find themselves dealing with the ac...

  3. Economic hardship and Mexican-origin adolescents' adjustment: examining adolescents' perceptions of hardship and parent-adolescent relationship quality.

    Science.gov (United States)

    Delgado, Melissa Y; Killoren, Sarah E; Updegraff, Kimberly A

    2013-10-01

    Studies examining economic hardship consistently have linked family economic hardship to adolescent adjustment via parent and family functioning, but limited attention has been given to adolescents' perceptions of these processes. To address this, the authors investigated the intervening effects of adolescents' perceptions of economic hardship and of parent-adolescent warmth and conflict on the associations between parental economic hardship and adolescent adjustment (i.e., depressive symptoms, risky behaviors, and school performance) in a sample of 246 Mexican-origin families. Findings revealed that both mothers' and fathers' reports of economic hardship were positively related to adolescents' reports of economic hardship, which in turn, were negatively related to parent-adolescent warmth and positively related to parent-adolescent conflict with both mothers and fathers. Adolescents' perceptions of economic hardship were indirectly related to (a) depressive symptoms through warmth with mothers and conflict with mothers and fathers, (b) involvement in risky behaviors through conflict with mothers and fathers, and (c) GPA through conflict with fathers. Our findings highlight the importance of adolescents' perceptions of family economic hardship and relationships with mothers and fathers in predicting adolescent adjustment.

  4. Social Support Seeking and Early Adolescent Depression and Anxiety Symptoms

    Science.gov (United States)

    Vélez, Clorinda E.; Krause, Elizabeth D.; McKinnon, Allison; Brunwasser, Steven M.; Freres, Derek R.; Abenavoli, Rachel M.; Gillham, Jane E.

    2016-01-01

    This study examined how social support seeking and rumination interacted to predict depression and anxiety symptoms 6 months later in early adolescents (N = 118; 11-14 years at baseline). We expected social support seeking would be more helpful for adolescents engaging in low rather than high levels of rumination. Adolescents self-reported on all…

  5. Mesopotamian medicine.

    Science.gov (United States)

    Retief, F P; Cilliers, L

    2007-01-01

    Although the Mesopotamian civilisation is as old as that of Egypt and might even have predated it, we know much less about Mesopotamian medicine, mainly because the cuneiform source material is less well researched. Medical healers existed from the middle of the 3rd millennium. In line with the strong theocratic state culture, healers were closely integrated with the powerful priestly fraternity, and were essentially of three main kinds: barû (seers) who were experts in divination, âshipu (exorcists), and asû (healing priests) who tended directly to the sick. All illness was accepted as sent by gods, demons and other evil spirits, either as retribution for sins or as malevolent visitations. Treatment revolved around identification of the offending supernatural power, appeasement of the angry gods, for example by offering amulets or incantations, exorcism of evil spirits, as well as a measure of empirical therapy aimed against certain recognised symptom complexes. Medical practice was rigidly codified, starting with Hammurabi's Code in the 18th century BC and persisting to the late 1st millennium BC. Works like the so-called Diagnostic Handbook, the Assyrian Herbal and Prescription Texts describe the rationale of Mesopotamian medicine, based predominantly on supernatural concepts, although rudimentary traces of empirical medicine are discernible. There is evidence that Egyptian medicine might have been influenced by Mesopotamian practices, but Greek rational medicine as it evolved in the 5th/4th centuries BC almost certainly had no significant Mesopotamian roots. PMID:17378276

  6. Travel medicine

    Science.gov (United States)

    Aw, Brian; Boraston, Suni; Botten, David; Cherniwchan, Darin; Fazal, Hyder; Kelton, Timothy; Libman, Michael; Saldanha, Colin; Scappatura, Philip; Stowe, Brian

    2014-01-01

    Abstract Objective To define the practice of travel medicine, provide the basics of a comprehensive pretravel consultation for international travelers, and assist in identifying patients who might require referral to travel medicine professionals. Sources of information Guidelines and recommendations on travel medicine and travel-related illnesses by national and international travel health authorities were reviewed. MEDLINE and EMBASE searches for related literature were also performed. Main message Travel medicine is a highly dynamic specialty that focuses on pretravel preventive care. A comprehensive risk assessment for each individual traveler is essential in order to accurately evaluate traveler-, itinerary-, and destination-specific risks, and to advise on the most appropriate risk management interventions to promote health and prevent adverse health outcomes during travel. Vaccinations might also be required and should be personalized according to the individual traveler’s immunization history, travel itinerary, and the amount of time available before departure. Conclusion A traveler’s health and safety depends on a practitioner’s level of expertise in providing pretravel counseling and vaccinations, if required. Those who advise travelers are encouraged to be aware of the extent of this responsibility and to refer all high-risk travelers to travel medicine professionals whenever possible. PMID:25500599

  7. Predicting Intra-Individual Academic Achievement Trajectories of Adolescents Nested in Class Environment: Influence of motivation, implicit theory of intelligence, self-esteem and parenting

    Directory of Open Access Journals (Sweden)

    Isabelle Roskam

    2007-05-01

    Full Text Available In a longitudinal study conducted on 1130 adolescents (557 male and 573 female in the 1st-6th grades from Belgian secondary schools, we tested the influence of individual factors (motivational constructs, implicit theory of intelligence and self-esteem and environmental determinants (parenting and class environment of academic achievement (grades in mathematics, language arts and GPA at three points in time. Using hierarchical linear models, we observed a decrease of grade over the course of the study, reciprocal relations between motivational constructs, self-esteem and academic achievement, a strong positive impact of supportive parenting and a moderate influence of class environment.

  8. Individuation or Identification? Self-Objectification and the Mother-Adolescent Relationship.

    Science.gov (United States)

    Katz-Wise, Sabra L; Budge, Stephanie L; Lindberg, Sara M; Hyde, Janet S

    2013-09-01

    Do adolescents model their mothers' self-objectification? We measured self-objectification (body surveillance and body shame), body mass index (BMI), body esteem, and quality of the mother-adolescent relationship in 179 female and 162 male adolescents at age 15, as well as self-objectification in their mothers. Initial analyses indicated no improvement in model fit if paths were allowed to differ for females and males; therefore a single model was tested for the combined sample. Findings revealed that mothers' body surveillance negatively predicted adolescents' body surveillance. Mothers' body shame was unrelated to adolescents' body shame, but positively predicted adolescents' body surveillance. Results for the relationship between mothers' and adolescents' self-objectification suggest that adolescents engaged in more individuation than modeling. A more positive mother-adolescent relationship predicted lower body shame and higher body esteem in adolescents, suggesting that the quality of the relationship with the mother may be a protective factor for adolescents' body image. Mother-adolescent relationship quality did not moderate the association between mothers' and adolescents' self-objectification. These findings contribute to our understanding about the sociocultural role of parents in adolescents' body image and inform interventions addressing negative body image in this age group. The quality of the mother-adolescent relationship is a clear point of entry for such interventions. Therapists should work with adolescents and their mothers toward a more positive relationship quality, which could then positively impact adolescents' body image. PMID:24363490

  9. Adolescents' protection motivation and smoking behaviour

    NARCIS (Netherlands)

    Thrul, J.; Stemmler, M.; Bühler, A.; Kuntsche, E.N.

    2013-01-01

    The protection motivation theory (PMT) is a well-known theory of behaviour change. This study tested the applicability of the sub-constructs of threat and coping appraisal in predicting adolescents' smoking-related behavioural intentions and smoking behaviour longitudinally. Adolescents (N = 494) ag

  10. Adolescent Literacy

    Science.gov (United States)

    Ippolito, Jacy, Ed.; Steele, Jennifer L., Ed.; Samson, Jennifer F., Ed.

    2012-01-01

    "Adolescent Literacy" initially appeared as a special issue of the "Harvard Educational Review". It explores key issues and debates in the adolescent literacy crisis, the popular use of cognitive strategies, and disciplinary and content-area literacy. Also examined are alternative forms of literacy, afterschool interventions, new instruction…

  11. Positively Adolescent!

    Science.gov (United States)

    Williamson, Sue

    2000-01-01

    Believes that music teachers should reassess their views toward adolescent behavior in the music classroom by learning to see their behavior in a positive light. Describes teaching strategies that build on four adolescent behaviors: (1) desire for peer acceptance; (2) abundant energy; (3) love of fun; and (4) limited time-managing skills. (CMK)

  12. Tibetan traditional medicine

    Institute of Scientific and Technical Information of China (English)

    2005-01-01

    Tibetan medicine companies in T.A.R can manufacture more than 360 Tibetan patent medicines. There are 18 Tibetan medicine factories in Tibet, and total out value exceeds 3 billion yuan. 24 kinds of Tibetan patent medicines have been incorporated into State Fundamental Medicine List, in which 14 Tibetan patent medicines are listed in national protected traditional medicine category.

  13. Do psychopathic traits assessed in mid-adolescence predict mental health, psychosocial, and antisocial, including criminal outcomes, over the subsequent 5 years?

    Science.gov (United States)

    Hemphälä, Malin; Hodgins, Sheilagh

    2014-01-01

    Objectif : Déterminer si les traits psychopathiques évalués à la mi-adolescence prédisent les résultats de santé mentale, psychosociaux, et antisociaux (y compris criminels) 5 ans plus tard et procurent par le fait même des avantages par rapport au diagnostic du trouble des conduites (TC). Méthode : Quatre-vingt-six femmes et 61 hommes ont été évalués à la mi-adolescence lors de leur première visite à une clinique pour abus de substances et ont été réévalués 5 ans plus tard. Les évaluations à l’adolescence comprennent la liste de psychopathie—version pour adolescents (PCL-YV), et selon leur âge, l’échelle des troubles affectifs pour enfants et de schizophrénie pour enfants d’âge scolaire, ou l’entrevue clinique structurée pour le Manuel diagnostique et statistique des troubles mentaux, 4e édition (SCID). Les évaluations au début de l’âge adulte comprenaient la SCID, les auto-déclarations du fonctionnement psychologique, du comportement agressif, de la criminalité et d’autres casiers judiciaires officiels. Résultats : Le score à l’élément antisocial prédisait positivement le nombre de symptômes d’anxiété et la probabilité de recevoir un traitement pour troubles d’utilisation de substances (TUS). Les scores aux éléments mode de vie et antisocial prédisaient négativement les scores à l’évaluation globale de fonctionnement. Par contre, le score interpersonnel et le sexe masculin prédisaient indépendamment et positivement le nombre de mois de travail ou d’études, tout comme l’interaction du mode de vie avec le sexe indiquait chez les hommes, mais pas chez les femmes, qu’une augmentation du score à l’élément mode de vie était associée à moins de temps de travail ou d’études. Les scores interpersonnel et antisocial prédisaient positivement le décrochage scolaire. Les scores à l’élément antisocial prédisaient le nombre de symptômes du trouble de la personnalité antisociale

  14. Medicinal Mushrooms

    NARCIS (Netherlands)

    Lindequist, U.; Won Kim, H.; Tiralongo, E.; Griensven, van L.J.L.D.

    2014-01-01

    Since beginning of mankind nature is the most important source of medicines. Bioactive compounds produced by living organisms can be used directly as drugs or as lead compounds for drug development. Besides, the natural material can be used as crude drug for preparation of powder or extracts. Plants

  15. [Osteopathic medicine].

    Science.gov (United States)

    Klein, P; Lepers, Y; Salem, W

    2011-09-01

    Osteopathy is originated in the 19th century in the United States. Andrew Taylor Still seek for an alternative medical system to the orthodox medicine largely empirical and advocating bloodletting, calomel, etc., all of which was resumed with terms like" heroic medicine". Osteopathy as other alternative medical practices (homeopathy, eclecticism, etc.) based on rational and metaphysical postulates as vitalism or the fact that man is a divinely ordained machine. Still's approach was essentially manual and based on manipulation of the joints. Today osteopaths challenge these dogmas and seek to agree their practice within scientific biomedical standards. Even if strong randomized clinical trials are lacking, several surveys report how osteopathy gained public notoriety. Several recent meta-analyses pinpoint the benefit of the spinal manipulative treatment and even if there is no evidence that such an approach is superior to other advocated therapies there is no evidence that these therapies are more effective than the first one. The major indications for such a treatment are cervical and low back pain, either chronic or acute. The quality of the relationship between the practitioner and patient together with the placebo effect are important components of a treatment effect. Osteopathic education is an important aspect and only higher education institutions, i.e. universities can achieve and maintain adequate standards. Materia medica and surgery represent the two major therapeutic mainstreams in medicine; osteopathy considered as manual medicine could be the third one. PMID:22034767

  16. Medicinal Plants.

    Science.gov (United States)

    Phillipson, J. David

    1997-01-01

    Highlights the demand for medicinal plants as pharmaceuticals and the demand for health care treatments worldwide and the issues that arise from this. Discusses new drugs from plants, anticancer drugs, antiviral drugs, antimalarial drugs, herbal remedies, quality, safety, efficacy, and conservation of plants. Contains 30 references. (JRH)

  17. Stages of Adolescence

    Science.gov (United States)

    ... Español Text Size Email Print Share Stages of Adolescence Page Content Article Body Adolescence, these years from puberty to adulthood, may be roughly divided into three stages: early adolescence, generally ages eleven to fourteen; middle adolescence, ages ...

  18. Development of in Silico Models for Predicting P-Glycoprotein Inhibitors Based on a Two-Step Approach for Feature Selection and Its Application to Chinese Herbal Medicine Screening.

    Science.gov (United States)

    Yang, Ming; Chen, Jialei; Shi, Xiufeng; Xu, Liwen; Xi, Zhijun; You, Lisha; An, Rui; Wang, Xinhong

    2015-10-01

    by developing an ensemble classification model to obtain more reliable predictions. Finally, we employed these models as a virtual screening tool for identifying potential P-gp inhibitors in Traditional Chinese Medicine Systems Pharmacology (TCMSP) database containing a total of 13 051 unique compounds from 498 herbs, resulting in 875 potential P-gp inhibitors and 15 inhibitor-rich herbs. These predictions were partly supported by a literature search and are valuable not only to develop novel P-gp inhibitors from TCM in the early stages of drug development, but also to optimize the use of herbal remedies.

  19. Factors that Influence Adolescents to Smoke.

    Science.gov (United States)

    Smith, Karen H.; Stutts, Mary Ann

    1999-01-01

    A survey of the factors that influence adolescents (n=246) to smoke found that family smoking behavior, peer pressure, and prior beliefs were more important in predicting smoking level than were advertising and antismoking information. (Author/JOW)

  20. [School difficulties in adolescence].

    Science.gov (United States)

    Schwarzenberg, T L; Buffone, M R; Scardia, C; Facente, C

    2002-12-01

    Loss, failure and desertion are those words, which better describe the most frequent difficulties incurred by teenagers, and their relation to the school environment, and indicate, as well, the lack of connection between individual aspirations and school achievements obtained. Despite the likelihood of school difficulties throughout the entire educational career, from the kindergarten to the college, we are able to recognize certain specific "disturbances" which come out during the adolescence, basically relating to the school experiences. School failure, school desertion and school abandonment are, in fact, issues mainly discussed in coincidence with the beginning of the adolescent age and the attending of the high school. The aetiopathogenesis of school discomfort is mostly determined by more than only one factor: psychological, physical, cognitive and environmental aspects, all together, contribute in various ways, to the rise and persisting of the above described problems. Suggesting a univocal characterization of the adolescent with school difficulties, is indeed a hard task, since school failure is not an exclusive feature of only one kind of personality or the expression of only one type of conflict. Once identified the individuals more subject to risk, and the warning signs of actual uneasiness, it is important therefore to intervene timely and in different ways in order to avoid the worsening or the excessive extension of the school difficulties and of their frequent and serious consequences on the teenagers' individual and domestic well-being. Such type of prevention definitely belongs to the Adolescent Medicine, and must be developed on different levels, by involving not only the teenagers, but also their families, the school, and the whole social environment in which the teenagers live and with which they interact.

  1. [School difficulties in adolescence].

    Science.gov (United States)

    Schwarzenberg, T L; Buffone, M R; Scardia, C; Facente, C

    2002-12-01

    Loss, failure and desertion are those words, which better describe the most frequent difficulties incurred by teenagers, and their relation to the school environment, and indicate, as well, the lack of connection between individual aspirations and school achievements obtained. Despite the likelihood of school difficulties throughout the entire educational career, from the kindergarten to the college, we are able to recognize certain specific "disturbances" which come out during the adolescence, basically relating to the school experiences. School failure, school desertion and school abandonment are, in fact, issues mainly discussed in coincidence with the beginning of the adolescent age and the attending of the high school. The aetiopathogenesis of school discomfort is mostly determined by more than only one factor: psychological, physical, cognitive and environmental aspects, all together, contribute in various ways, to the rise and persisting of the above described problems. Suggesting a univocal characterization of the adolescent with school difficulties, is indeed a hard task, since school failure is not an exclusive feature of only one kind of personality or the expression of only one type of conflict. Once identified the individuals more subject to risk, and the warning signs of actual uneasiness, it is important therefore to intervene timely and in different ways in order to avoid the worsening or the excessive extension of the school difficulties and of their frequent and serious consequences on the teenagers' individual and domestic well-being. Such type of prevention definitely belongs to the Adolescent Medicine, and must be developed on different levels, by involving not only the teenagers, but also their families, the school, and the whole social environment in which the teenagers live and with which they interact. PMID:12388952

  2. Pregnancy and Medicines

    Science.gov (United States)

    Not all medicines are safe to take when you are pregnant. Some medicines can harm your baby. That includes over-the- ... care provider before you start or stop any medicine. Not using medicine that you need may be ...

  3. Complementary and Alternative Medicine

    Science.gov (United States)

    ... Help a Friend Who Cuts? Complementary and Alternative Medicine KidsHealth > For Teens > Complementary and Alternative Medicine Print ... replacement. continue How Is CAM Different From Conventional Medicine? Conventional medicine is based on scientific knowledge of ...

  4. Transfusion Medicine

    Directory of Open Access Journals (Sweden)

    Smit Sibinga CT

    2013-07-01

    Full Text Available Cees Th. Smit Sibinga ID Consulting, Zuidhorn, The NetherlandsTransfusion Medicine is a bridging science, spanning the evidence-based practice at the bedside with the social sciences in the community.     Transfusion Medicine starts at the bedside. Surprisingly, only recently that has become rediscovered with the development of ‘patient blood management’ and ‘patient centered’ approaches to allow the growth of an optimal and rational patient care through supportive hemotherapy – safe and effective, affordable and accessible.1    Where transfusion of blood found its origin in the need of a patient, it has drifted away for a long period of time from the bedside and has been dominated for almost a century by laboratory sciences. At least the first ten editions of the famous and well reputed textbook Mollison’s Blood Transfusion in Clinical Medicine contained only a fraction on the actual bedside practice of transfusion medicine and did not focus at all on patient blood management.2    This journal will focus on all aspects of the transfusion chain that immediately relate to the bedside practice and clinical use of blood and its components, and plasma derivatives as integral elements of a human transplant tissue. That includes legal and regulatory aspects, medical, ethical and cultural aspects, pure science and pathophysiology of disease and the impact of transfusion of blood, as well as aspects of the epidemiology of blood transfusion and clinical indications, and cost-effectiveness. Education through timely and continued transfer of up to date knowledge and the application of knowledge in clinical practice to develop and maintain clinical skills and competence, with the extension of current educational approaches through e-learning and accessible ‘apps’ will be given a prominent place.

  5. Personcentreret medicin

    DEFF Research Database (Denmark)

    Hvas, Lotte

    2015-01-01

    Personcentreret medicin tager udgangspunkt i den person, lægen møder, hvad enten vedkommende er rask eller syg, og bygger på værdier som fortrolighed, kontinuitet, nærvær, tillid og tilgængelighed. Det er patientens dagsorden, der gælder, og lægen kan i fællesskab med patienten (baseret på en...

  6. Medicine partnerships

    OpenAIRE

    Cramer, J.

    2003-01-01

    Partial medication compliance, where patients do not take enough of their prescribed medicine to achieve adequate outcomes, is common. Research using electronic monitoring to assess compliance has shown that people take approximately 75% of doses as prescribed, irrespective of the condition being treated or its severity. Erratic compliance often leads to discontinuation of therapy, as treatment is perceived to be ineffective. Compliance decreases as frequency of dosing increases. Inadequate c...

  7. Haptic medicine.

    Science.gov (United States)

    Mason, Cindy; Mason, Earl

    2009-01-01

    The paper introduces haptic medicine--healthcare based on loving touch for healing and preventing disease. We describe the effects of loving touch (a square inch of our skin has over 1000 nerves) on the body, brain and mind. We describe two web-based health education and media projects. The first, HYPERLINK "http://www.21stcenturymed.org" www.21stcenturymed.org is a place for health practitioners to start learning about touch and resources. The second project, Humans Without Borders, is a multi-lingual self help education website for everyday people. Teaching materials for these projects are based on our previous work with a form of haptic medicine known as psychophysiophilosophy with patients at Stanford Hospital, Kaiser Permanente and Lucille Packard Children's Hospital. We describe psychophysiophilosophy, relate motherly love to recent discoveries in neurosciences and give hints on ways to increase motherly love in each of us. We present a plan for moving into the future by re-introducing haptic medicine into our daily lives through self-help and as an adjunct for current physician practice. There is an exercise in self-help for the reader and an appendix of recent clinical research with profound benefits on the use of human touch for over 40 conditions. PMID:19745495

  8. Medicinal electrochemistry: integration of electrochemistry, medicinal chemistry and computational chemistry.

    Science.gov (United States)

    Almeida, M O; Maltarollo, V G; de Toledo, R A; Shim, H; Santos, M C; Honorio, K M

    2014-01-01

    Over the last centuries, there were many important discoveries in medicine that were crucial for gaining a better understanding of several physiological processes. Molecular modelling techniques are powerful tools that have been successfully used to analyse and interface medicinal chemistry studies with electrochemical experimental results. This special combination can help to comprehend medicinal chemistry problems, such as predicting biological activity and understanding drug action mechanisms. Electrochemistry has provided better comprehension of biological reactions and, as a result of many technological improvements, the combination of electrochemical techniques and biosensors has become an appealing choice for pharmaceutical and biomedical analyses. Therefore, this review will briefly outline the present scope and future advances related to the integration of electrochemical and medicinal chemistry approaches based on various applications from recent studies. PMID:24533810

  9. Nuclear medicine applications for the diabetic foot

    Energy Technology Data Exchange (ETDEWEB)

    Hartshorne, M.F.; Peters, V.

    1987-04-01

    Although not frequently described in the podiatric literature, nuclear medicine imaging may be of great assistance to the clinical podiatrist. This report reviews in detail the use of modern nuclear medicine approaches to the diagnosis and management of the diabetic foot. Nuclear medicine techniques are helpful in evaluating possible osteomyelitis, in determining appropriate amputation levels, and in predicting response to conservative ulcer management. Specific indications for bone, gallium, and perfusion imaging are described.

  10. Precision Medicine, Cardiovascular Disease and Hunting Elephants.

    Science.gov (United States)

    Joyner, Michael J

    2016-01-01

    Precision medicine postulates improved prediction, prevention, diagnosis and treatment of disease based on patient specific factors especially DNA sequence (i.e., gene) variants. Ideas related to precision medicine stem from the much anticipated "genetic revolution in medicine" arising seamlessly from the human genome project (HGP). In this essay I deconstruct the concept of precision medicine and raise questions about the validity of the paradigm in general and its application to cardiovascular disease. Thus far precision medicine has underperformed based on the vision promulgated by enthusiasts. While niche successes for precision medicine are likely, the promises of broad based transformation should be viewed with skepticism. Open discussion and debate related to precision medicine are urgently needed to avoid misapplication of resources, hype, iatrogenic interventions, and distraction from established approaches with ongoing utility. Failure to engage in such debate will lead to negative unintended consequences from a revolution that might never come. PMID:26902518

  11. An analysis of adolescent suicide attempts: the expendable child.

    Science.gov (United States)

    Woznica, J G; Shapiro, J R

    1990-12-01

    Assessed the concept of the "expendable child" syndrome proposed by Sabbath (1969) as a contributing factor in adolescent suicide attempts. It was hypothesized that suicidal adolescents would be rated higher on a measure of "expendability" than would a psychiatric control group of adolescents with no known history of suicide attempts or ideation. Forty adolescents, ages 13-24, who had been seen in psychotherapy at a teen-age health clinic, were rated by their psychotherapists on suicidality and a 12-item scale of expendability (a sense of being unwanted and/or a burden on the family). As predicted, suicidal adolescents received significantly higher ratings on the expendability measure than nonsuicidal adolescents. Results support the concept that feeling expendable is a characteristic of suicidal adolescents. Implications for prevention and treatment of adolescent suicidality are discussed.

  12. Psychosocial and Health-Related Characteristics of Adolescent Television Viewers.

    Science.gov (United States)

    Page, Randy M.; And Others

    1996-01-01

    Examined relationship between television viewing frequency and adolescents' health-related and psychosocial characteristics. Found that shyness and exercise frequency predicted television viewing frequency. Among females, exercise frequency, shyness, loneliness, and perceived attractiveness predicted viewing frequency. Light viewers exercised more…

  13. The Use of the Peabody Picture Vocabulary Test with Emotionally Disturbed Adolescents.

    Science.gov (United States)

    Dean, Raymond S.

    1980-01-01

    The validity and reliability of the Peabody Picture Vocabulary Test was estimated with emotionally disturbed adolescents. Results indicated that the power of the test to predict future achievement of emotionally disturbed adolescents is comparable to that expected for normals. (Author)

  14. Longitudinal assessment of autonomy and relatedness in adolescent-family interactions as predictors of adolescent ego development and self-esteem.

    Science.gov (United States)

    Allen, J P; Hauser, S T; Bell, K L; O'Connor, T G

    1994-02-01

    This study examined links between processes of establishing autonomy and relatedness in adolescent-family interactions and adolescents' psychosocial development. Adolescents in 2-parent families and their parents were observed in a revealed-differences interaction task when adolescents were 14, and adolescents' ego development and self-esteem were assessed at both 14 and 16. Developmental indices were strongly related to autonomy and relatedness displayed by both parents and adolescents. Significant variance was explained even after accounting for the number and quality of speeches of each family member as rated by a different, well-validated family coding system. Increases in adolescents' ego development and self-esteem over time were predicted by fathers' behaviors challenging adolescents' autonomy and relatedness, but only when these occurred in the context of fathers' overall display of autonomous-relatedness with the adolescent. The importance of the mutually negotiated process of adolescents' exploration from the secure base of parental relationships is discussed.

  15. Interactions Between Internalizing Symptoms and Urgency in the Prediction of Alcohol Use and Expectancies Among Low-Income, Minority Early Adolescents

    Science.gov (United States)

    Marmorstein, Naomi R.

    2015-01-01

    This study examined whether urgency, a disposition to rash action under conditions of strong emotion, moderates associations between internalizing symptoms and alcohol use and related expectancies. Data from the Camden Youth Development Study, a longitudinal, community-based study of early adolescents (N = 144, mean age at intake = 11.9 years; 65% Hispanic, 30% African-American; 50% male), were used. Self-report questionnaire measures of depressive symptoms, social and generalized anxiety symptoms, urgency, alcohol use, and alcohol expectancies were used. Mixed models were used to examine the effects of internalizing symptoms, urgency, and their interaction on alcohol use and expectancy trajectories over time. Depressive symptoms interacted with urgency such that youth with high levels of both tended to have elevated levels of global positive alcohol expectancies. Social anxiety symptoms interacted with urgency to be associated with increasing levels of social behavior alcohol expectancies such that youth with high levels of both tended to experience particular increases in these expectancies over time. Generalized anxiety was not found to be associated with alcohol-related constructs. Therefore, high levels of urgency combine with depressive and social anxiety symptoms to be associated with particularly increased risk for alcohol expectancies that are associated with later alcohol use and problems, indicating particular risk for youth with these combinations of personality traits and psychopathology symptoms. PMID:27512337

  16. Do adolescent drug use consequences predict externalizing and internalizing problems in emerging adulthood as well as traditional drug use measures in a Hispanic sample?

    Science.gov (United States)

    Grigsby, Timothy J; Forster, Myriam; Baezconde-Garbanati, Lourdes; Soto, Daniel W; Unger, Jennifer B

    2014-03-01

    The present study compares statistical models for three conceptualizations of drug use in 11th grade (past 30 day ever/never use, past 30 day frequency of drug use and past 30 day drug use consequences) with externalizing and internalizing problems in emerging adulthood when controlling for age, academic achievement and socioeconomic status in a Hispanic sample. Multivariate logistic regression models for the different drug use variables were compared when modeling weapon carrying, arrest, multiple lifetime sex partners, drug/alcohol use before sex and condom use in emerging adulthood. A multivariate linear regression model was used to model depression in emerging adulthood as a function of drug use measurement controlling for other covariates and depression in adolescence. Our findings suggest that any conceptualization of drug use will produce equitable results and model fit statistics when examining externalizing problems. However, when investigating internalizing problems, such as depression, lower frequency drug use-and not high frequency-was more strongly associated with depression whereas experiencing high levels of drug use consequences-and not low levels of consequences-was associated with depression in emerging adulthood despite similar model fit values. Variation between drug use and the experience of drug use consequences may lead to misspecification of "at-risk" subgroups of drug users. Implications and future directions are discussed. PMID:24345310

  17. Adding insult to injury: childhood and adolescent risk factors for psychosis predict lower fractional anisotropy in the superior longitudinal fasciculus in healthy adults.

    Science.gov (United States)

    DeRosse, Pamela; Ikuta, Toshikazu; Peters, Bart D; Karlsgodt, Katherine H; Szeszko, Philip R; Malhotra, Anil K

    2014-12-30

    Although epidemiological studies provide strong support for demographic and environmental risk factors in psychotic disorders, few data examine how these risk factors relate to the putative aberrant neurodevelopment associated with illness. The present study examined how the accumulation of risk factors including low IQ, low parental socioeconomic status (SES), history of adolescent cannabis use and childhood trauma, and high levels of subclinical psychotic-like experiences (PLEs) contributed to aberrant neurodevelopmental outcomes in 112 otherwise healthy adults recruited from the community. Participants were studied with diffusion tensor imaging (DTI), and voxel-wise statistical analysis of fractional anisotropy (FA) using tract-based spatial statistics (TBSS) was used to examine the relation between cumulative risk (CR) for psychosis and white matter (WM) integrity across the whole brain. Analyses revealed that higher CR was significantly associated with lower FA in a cluster in the left superior longitudinal fasciculus (SLF). These results suggest that risk factors previously associated with psychotic disorders are associated with WM integrity even in otherwise healthy adults and may provide insight into how previously identified risk factors contribute to the structural brain abnormalities associated with psychotic illness. Prospective longitudinal studies examining the effect of risk factors on the developmental trajectory of brain WM are warranted. PMID:25277095

  18. Adolescent Mothers' Adjustment to Parenting.

    Science.gov (United States)

    Samuels, Valerie Jarvis; And Others

    1994-01-01

    Examined adolescent mothers' adjustment to parenting, self-esteem, social support, and perceptions of baby. Subjects (n=52) responded to questionnaires at two time periods approximately six months apart. Mothers with higher self-esteem at Time 1 had better adjustment at Time 2. Adjustment was predicted by Time 2 variables; contact with baby's…

  19. Treatment of adolescent idiopathic scoliosis by high-qualitive traction and Chinese medicine fumigation combined with chiropractic manipulation%优值牵引、中药熏蒸联合整脊手法治疗青少年特发性腰椎侧凸

    Institute of Scientific and Technical Information of China (English)

    张梦雨; 鲍铁周; 宋永伟; 李洋

    2016-01-01

    Objective: To observe the clinical effect of high-qualitive traction and Chinese medicine fumigation combined with chiropractic manipulation in the treatment of adolescent idiopathic scoliosis. Method: 48 patients with adolescent idiopathic scoliosis between February 2013 and March 2015 from were treated with high-qualitive traction and Chinese medicine fumigation combined with chiropractic manipulation. The VAS score, ODI score and Cobb change were compared before and after treatment. Result: After the treatment, the VAS score, ODI score and Cobb angle were decreased, and the difference between the three indicators were statistically significant(P<0.01). Conclusion: The treatment of AIS with high-qualitive traction and Chinese medicine fumigation combined with chiropractic manipulation can effectively improve the functional activity of patients, reduce the pain of patients with the advantages of simple operation, less injury and high safety.%目的:观察优值牵引、中药熏蒸联合整脊手法治疗青少年特发性腰椎侧凸的临床疗效。方法:2013年2月—2015年3月采用优值牵引、中药熏蒸联合整脊手法治疗青少年特发性脊柱侧弯患者48例,对比治疗前后患者VAS疼痛评分、ODI评分及Cobb角的变化。结果:疗程结束后患者的VAS疼痛评分、ODI评分及Cobb角均减小,且三项指标治疗前后差异具有统计学意义(P<0.01)。结论:优值牵引、中药熏蒸联合整脊手法治疗 AIS,可有效地改善患者功能活动,减轻患者疼痛,具有操作简便、无创安全等特点。

  20. A longitudinal study of Hong Kong adolescents' and parents' perceptions of family functioning and well-being.

    Science.gov (United States)

    Shek, D T

    1998-12-01

    In this longitudinal study, the relationships between Hong Kong Chinese adolescents' and parents' discrepancies in their perceptions of family functioning and adolescents' psychological well-being were investigated via adolescents' and parents' reports of family functioning (N = 378 families). Results showed that discrepancies in perceptions of family functioning between adolescents and parents were related to adolescents' feelings of hopelessness, life satisfaction, self-esteem, purpose in life, and general psychiatric morbidity at Time 1 and Time 2. Longitudinal and prospective analyses (Time 1 predictors predicting Time 2 criterion variables) suggested that the relationship between discrepancies in perceptions of family functioning and adolescents' psychological well-being are bidirectional. Adolescent-father and adolescent-mother discrepancies had similar effects on adolescents' psychological well-being. The negative impact of discrepancies among family members in perceptions of family functioning on adolescents' psychological well-being was greater for adolescent girls than for adolescent boys. PMID:9845971