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Sample records for adl cps rug-i

  1. A Selective CPS Transformation

    DEFF Research Database (Denmark)

    Nielsen, Lasse Riechstein

    2001-01-01

    characterize this involvement as a control effect and we present a selective CPS transformation that makes functions and expressions continuation-passing if they have a control effect, and that leaves the rest of the program in direct style. We formalize this selective CPS transformation with an operational...

  2. CA/CPS: A Communications ZEBRA implementation using CPS

    International Nuclear Information System (INIS)

    Roberts, L.A.

    1991-05-01

    CZ/CPS is an implementation of the Communications ZEBRA distributed computing environment utilizing the CPS communications protocol. CZ/CPS is intended for parallelization of high energy physics application programs using the CERN Program Library memory and data structure management features. CZ/CPS provides transparent communication of ZEBRA data structures among cooperative processes using standard interfaces for ZEBRA I/O. Examples of usage in a CPS HBOOK4 and GEANT3 application are provided

  3. CPS and the Fermilab farms

    International Nuclear Information System (INIS)

    Fausey, M.R.

    1992-06-01

    Cooperative Processes Software (CPS) is a parallel programming toolkit developed at the Fermi National Accelerator Laboratory. It is the most recent product in an evolution of systems aimed at finding a cost-effective solution to the enormous computing requirements in experimental high energy physics. Parallel programs written with CPS are large-grained, which means that the parallelism occurs at the subroutine level, rather than at the traditional single line of code level. This fits the requirements of high energy physics applications, such as event reconstruction, or detector simulations, quite well. It also satisfies the requirements of applications in many other fields. One example is in the pharmaceutical industry. In the field of computational chemistry, the process of drug design may be accelerated with this approach. CPS programs run as a collection of processes distributed over many computers. CPS currently supports a mixture of heterogeneous UNIX-based workstations which communicate over networks with TCP/IR CPS is most suited for jobs with relatively low I/O requirements compared to CPU. The CPS toolkit supports message passing remote subroutine calls, process synchronization, bulk data transfers, and a mechanism called process queues, by which one process can find another which has reached a particular state. The CPS software supports both batch processing and computer center operations. The system is currently running in production mode on two farms of processors at Fermilab. One farm consists of approximately 90 IBM RS/6000 model 320 workstations, and the other has 85 Silicon Graphics 4D/35 workstations. This paper first briefly describes the history of parallel processing at Fermilab which lead to the development of CPS. Then the CPS software and the CPS Batch queueing system are described. Finally, the experiences of using CPS in production on the Fermilab processor farms are described

  4. CPS and the Fermilab farms

    Energy Technology Data Exchange (ETDEWEB)

    Fausey, M.R.

    1992-06-01

    Cooperative Processes Software (CPS) is a parallel programming toolkit developed at the Fermi National Accelerator Laboratory. It is the most recent product in an evolution of systems aimed at finding a cost-effective solution to the enormous computing requirements in experimental high energy physics. Parallel programs written with CPS are large-grained, which means that the parallelism occurs at the subroutine level, rather than at the traditional single line of code level. This fits the requirements of high energy physics applications, such as event reconstruction, or detector simulations, quite well. It also satisfies the requirements of applications in many other fields. One example is in the pharmaceutical industry. In the field of computational chemistry, the process of drug design may be accelerated with this approach. CPS programs run as a collection of processes distributed over many computers. CPS currently supports a mixture of heterogeneous UNIX-based workstations which communicate over networks with TCP/IR CPS is most suited for jobs with relatively low I/O requirements compared to CPU. The CPS toolkit supports message passing remote subroutine calls, process synchronization, bulk data transfers, and a mechanism called process queues, by which one process can find another which has reached a particular state. The CPS software supports both batch processing and computer center operations. The system is currently running in production mode on two farms of processors at Fermilab. One farm consists of approximately 90 IBM RS/6000 model 320 workstations, and the other has 85 Silicon Graphics 4D/35 workstations. This paper first briefly describes the history of parallel processing at Fermilab which lead to the development of CPS. Then the CPS software and the CPS Batch queueing system are described. Finally, the experiences of using CPS in production on the Fermilab processor farms are described.

  5. SecureCPS: Defending a nanosatellite cyber-physical system

    Science.gov (United States)

    Forbes, Lance; Vu, Huy; Udrea, Bogdan; Hagar, Hamilton; Koutsoukos, Xenofon D.; Yampolskiy, Mark

    2014-06-01

    Recent inexpensive nanosatellite designs employ maneuvering thrusters, much as large satellites have done for decades. However, because a maneuvering nanosatellite can threaten HVAs on-­orbit, it must provide a level of security typically reserved for HVAs. Securing nanosatellites with maneuvering capability is challenging due to extreme cost, size, and power constraints. While still in the design process, our low-­cost SecureCPS architecture promises to dramatically improve security, to include preempting unknown binaries and detecting abnormal behavior. SecureCPS also applies to a broad class of cyber-­physical systems (CPS), such as aircraft, cars, and trains. This paper focuses on Embry-­Riddle's ARAPAIMA nanosatellite architecture, where we assume any off-­the-­shelf component could be compromised by a supply chain attack.1 Based on these assumptions, we have used Vanderbilt's Cyber Physical -­ Attack Description Language (CP-­ADL) to represent realistic attacks, analyze how these attacks propagate in the ARAPAIMA architecture, and how to defeat them using the combination of a low-­cost Root of Trust (RoT) Module, Global InfoTek's Advanced Malware Analysis System (GAMAS), and Anomaly Detection by Machine Learning (ADML).2 Our most recent efforts focus on refining and validating the design of SecureCPS.

  6. BCD/CPS: An event-level GEANT3 parallelization via CPS

    International Nuclear Information System (INIS)

    Roberts, L.A.

    1991-04-01

    BCD/CPS is an implementation of the Bottom Collider Detector GEANT3 simulation for CPS processor ranches. BCD/CPS demonstrates some of the capabilities of event-parallel applications applicable to current SSC detector simulations using the CPS and CZ/CPS communications protocols. Design, implementation and usage of the BCD/CPS simulation are presented along with extensive source listings for novice GEANT3/CPS programmers. 11 refs

  7. Ineffective ADL skills in women with fibromyalgia

    DEFF Research Database (Denmark)

    Von Bülow, Cecilie; Amris, Kirstine; la Cour, Karen

    2016-01-01

    BACKGROUND: Subgroups of women with fibromyalgia likely show different activity of daily living (ADL) skill deficits. Identifying ineffective ADL skills of significance in the 'typical' woman with fibromyalgia will promote the planning of targeted occupational therapy interventions aiming...... at improving ADL ability. OBJECTIVE: To identify frequently reported ADL skill deficits of significance in subgroups of women with fibromyalgia who have decreased ADL motor ability in combination with decreased or competent ADL process ability. METHOD: Women with fibromyalgia were evaluated with the Assessment...... of Motor and Process Skills (AMPS). If they demonstrated decreased ADL motor ability, the calibrated AMPS raters identified and reported ineffective ADL skills of significance. Descriptive comparisons were made between subgroups displaying either decreased or competent ADL process ability. RESULTS: Moves...

  8. CPS Transformation of Beta-Redexes

    DEFF Research Database (Denmark)

    Danvy, Olivier; Nielsen, Lasse

    2005-01-01

    The extra compaction of the most compacting CPS transformation in existence, which is due to Sabry and Felleisen, is generally attributed to (1) making continuations occur first in CPS terms and (2) classifying more redexes as administrative. We show that this extra compaction is actually...... independent of the relative positions of values and continuations and furthermore that it is solely due to a context-sensitive transformation of beta-redexes. We stage the more compact CPS transformation into a first-order uncurrying phase and a context-insensitive CPS transformation. We also define a context......-insensitive CPS transformation that provides the extra compaction. This CPS transformation operates in one pass and is dependently typed....

  9. CPS Transformation of Beta-Redexes

    DEFF Research Database (Denmark)

    Danvy, Olivier; Nielsen, Lasse R.

    2000-01-01

    The extra compaction of the most compacting CPS transformation in existence, which is due to Sabry and Felleisen, is generally attributed to (1) making continuations occur first in CPS terms and (2) classifying more redexes as administrative. We show that this extra compaction is actually...... independent of the relative positions of values and continuations and furthermore that it is solely due to a context-sensitive transformation of beta-redexes. We stage the more compact CPS transformation into a first-order uncurrying phase and a context-insensitive CPS transformation. We also define a context......-insensitive CPS transformation that provides the extra compaction. This CPS transformation operates in one pass and is dependently typed....

  10. An Operational Investigation of the CPS Hierarchy

    DEFF Research Database (Denmark)

    Danvy, Olivier; Yang, Zhe

    1999-01-01

    We explore the hierarchy of control induced by successive transformations into continuation-passing style (CPS) in the presence of “control delimiters ” and “composable continuations ”. Specifically, we investigate the structural operational semantics associated with the CPS hierarchy. To this end......, we characterize an operational notion of continuation semantics. We relate it to the traditional CPS transformation and we use it to account for the control operator shift and the control delimiter reset operationally. We then transcribe the resulting continuation semantics in ML, thus obtaining...

  11. An Operational Investigation of the CPS Hierarchy

    DEFF Research Database (Denmark)

    Danvy, Olivier; Yang, Zhe

    1998-01-01

    We explore the hierarchy of control induced by successive transformations into continuation-passing style (CPS) in the presence of “control delimiters ” and “composable continuations ”. Specifically, we investigate the structural operational semantics associated with the CPS hierarchy. To this end......, we characterize an operational notion of continuation semantics. We relate it to the traditional CPS transformation and we use it to account for the control operator shift and the control delimiter reset operationally. We then transcribe the resulting continuation semantics in ML, thus obtaining...

  12. Trainee Occupational Therapists Scoring the Barthel ADL.

    Science.gov (United States)

    Martin, Elizabeth; Nugent, Chris; Bond, Raymond; Martin, Suzanne

    2015-09-01

    Within medical applications there are two main types of information design; paper-based and digital information [1]. As technology is constantly changing, information within healthcare management and delivery is continually being transitioned from traditional paper documents to digital and online resources. Activity of Daily Living (ADL) charts are still predominantly paper based and are therefore prone to "human error" [2]. In light of this, an investigation has taken place into the design for reducing the amount of human error, between a paper based ADL, specifically the Barthel Index, and the same ADL created digitally. The digital ADL was developed as an online platform as this offers the best method of data capture for a large group of participants all together [3]. The aim of the study was to evaluate the usability of the Barthel Index ADL in paper format and then reproduce the same ADL digitally. This paper presents the findings of a study involving 26 participants who were familiar with ADL charts, and used three scenarios requiring them to complete both a paper ADL and a digital ADL. An evaluation was undertaken to ascertain if there were any 'human errors' in completing the paper ADL and also to find similarities/differences through using the digital ADL. The results from the study indicated that 22/26 participants agreed that the digital ADL was better, if not the same as a paper based ADL. Further results indicated that participants rate highly the added benefit of the digital ADL being easy to use and also that calculation of assessment scores were performed automatically. Statistically the digital BI offered a 100 % correction rate in the total calculation, in comparison to the paper based BI where it is more common for users to make mathematical calculation errors. Therefore in order to minimise handwriting and calculation errors, the digital BI proved superior than the traditional paper based method.

  13. CPS Transformation of Flow Information, Part II

    DEFF Research Database (Denmark)

    Damian, D.; Danvy, Olivier

    2003-01-01

    consider the administrative reductions of a Plotkin-style transformation into Continuation-Passing Style (CPS), and how they affect the result of a constraint-based control-flow analysis and, in particular, the least element in the space of solutions. We show that administrative reductions preserve...... the least solution. Preservation of least solutions solves a problem that was left open in Palsberg and Wand's article ‘CPS Transformation of Flow Information.’ Together, Palsberg and Wand's article and the present article show how to map in linear time the least solution of the flow constraints...... of a program into the least solution of the flow constraints of the CPS counterpart of this program, after administrative reductions. Furthermore, we show how to CPS transform control-flow information in one pass....

  14. On proving syntactic properties of CPS programs

    DEFF Research Database (Denmark)

    Danvy, Olivier; Dzafic, Belmina; Pfenning, Frank

    1999-01-01

    Higher-order program transformations raise new challenges for proving properties of their output, since they resist traditional, first-order proof techniques. In this work, we consider (1) the “one-pass” continuation-passing style (CPS) transformation, which is second-order, and (2) the occurrences...... of parameters of continuations in its output. To this end, we specify the one-pass CPS transformation relationally and we use the proof technique of logical relations....

  15. An Extensional CPS Transform (Preliminary Report)

    DEFF Research Database (Denmark)

    Filinski, Andrzej

    2001-01-01

    We shoe that, in a language wihg general continuation-effects, the syntactic, or intensional, CPS transform is mirrored by a semantic, or extensional, functional term. In other words, form only the observable behavior any direct-style term (possibly containing the usual first-class continuation...... primitives), we can uniformly extract the observable behavior of its CPS counterpart. As a consequence of this result, we show that the computational lambda-calculus is complete for observational equivalence of pure, simply typed lambda-terms in Scheme-like contexts....

  16. Classical realizability in the CPS target language

    DEFF Research Database (Denmark)

    Frey, Jonas

    2016-01-01

    Motivated by considerations about Krivine's classical realizability, we introduce a term calculus for an intuitionistic logic with record types, which we call the CPS target language. We give a reformulation of the constructions of classical realizability in this language, using the categorical...... techniques of realizability triposes and toposes. We argue that the presentation of classical realizability in the CPS target language simplifies calculations in realizability toposes, in particular it admits a nice presentation of conjunction as intersection type which is inspired by Girard's ludics....

  17. On proving syntactic properties of CPS programs

    DEFF Research Database (Denmark)

    Danvy, Olivier; Dzafic, Belmina; Pfenning, Frank

    1999-01-01

    Higher-order program transformations raise new challenges for proving properties of their output, since they resist traditional, first-order proof techniques. In this work, we consider (1) the “one-pass” continuation-passing style (CPS) transformation, which is second-order, and (2) the occurrences...

  18. A Simple CPS Transformation of Control-Flow Information

    DEFF Research Database (Denmark)

    Damian, Daniel; Danvy, Olivier

    2002-01-01

    We build on Danvy and Nielsen's first-order program transformation into continuation-passing style (CPS) to design a new CPS transformation of flow information that is simpler and more efficient than what has been presented in previous work. The key to simplicity and efficiency is that our CPS tr...

  19. A First-Order One-Pass CPS Transformation

    DEFF Research Database (Denmark)

    Danvy, Olivier; Nielsen, Lasse Reichstein

    2001-01-01

    We present a new transformation of λ-terms into continuation-passing style (CPS). This transformation operates in one pass and is both compositional and first-order. Previous CPS transformations only enjoyed two out of the three properties of being first-order, one-pass, and compositional......, but the new transformation enjoys all three properties. It is proved correct directly by structural induction over source terms instead of indirectly with a colon translation, as in Plotkin's original proof. Similarly, it makes it possible to reason about CPS-transformed terms by structural induction over...... source terms, directly.The new CPS transformation connects separately published approaches to the CPS transformation. It has already been used to state a new and simpler correctness proof of a direct-style transformation, and to develop a new and simpler CPS transformation of control-flow information....

  20. A First-Order One-Pass CPS Transformation

    DEFF Research Database (Denmark)

    Danvy, Olivier; Nielsen, Lasse Reichstein

    2003-01-01

    We present a new transformation of λ-terms into continuation-passing style (CPS). This transformation operates in one pass and is both compositional and first-order. Previous CPS transformations only enjoyed two out of the three properties of being first-order, one-pass, and compositional......, but the new transformation enjoys all three properties. It is proved correct directly by structural induction over source terms instead of indirectly with a colon translation, as in Plotkin's original proof. Similarly, it makes it possible to reason about CPS-transformed terms by structural induction over...... source terms, directly.The new CPS transformation connects separately published approaches to the CPS transformation. It has already been used to state a new and simpler correctness proof of a direct-style transformation, and to develop a new and simpler CPS transformation of control-flow information....

  1. International Conference ML4CPS 2016

    CERN Document Server

    Niggemann, Oliver; Kühnert, Christian

    2017-01-01

    The work presents new approaches to Machine Learning for Cyber Physical Systems, experiences and visions. It contains some selected papers from the international Conference ML4CPS – Machine Learning for Cyber Physical Systems, which was held in Karlsruhe, September 29th, 2016. Cyber Physical Systems are characterized by their ability to adapt and to learn: They analyze their environment and, based on observations, they learn patterns, correlations and predictive models. Typical applications are condition monitoring, predictive maintenance, image processing and diagnosis. Machine Learning is the key technology for these developments. The Editors Prof. Dr.-Ing. Jürgen Beyerer is Professor at the Department for Interactive Real-Time Systems at the Karlsruhe Institute of Technology. In addition he manages the Fraunhofer Institute of Optronics, System Technologies and Image Exploitation IOSB. Prof. Dr. Oliver Niggemann is Professor for Embedded Software Engineering. His research interests are in the field of Di...

  2. Fluid Ability (Gf) and Complex Problem Solving (CPS)

    OpenAIRE

    Patrick Kyllonen; Cristina Anguiano Carrasco; Harrison J. Kell

    2017-01-01

    Complex problem solving (CPS) has emerged over the past several decades as an important construct in education and in the workforce. We examine the relationship between CPS and general fluid ability (Gf) both conceptually and empirically. A review of definitions of the two factors, prototypical tasks, and the information processing analyses of performance on those tasks suggest considerable conceptual overlap. We review three definitions of CPS: a general definition emerging from the human pr...

  3. Sensitivity of different ADL measures to apraxia and motor impairments

    NARCIS (Netherlands)

    Donkervoort, M; Dekker, Joost; Deelman, BG

    Objective: To determine whether specifically designed activities of daily living (ADL) observations can measure disability due to apraxia with more sensitivity than the Barthel ADL Index, a conventional functional scale. Design: Cross-sectional study. Setting: Rehabilitation centres and nursing

  4. Sensitivity of different ADL measures to apraxia and motor impairments.

    Science.gov (United States)

    Donkervoort, Mireille; Dekker, Joost; Deelman, Betto G

    2002-05-01

    To determine whether specifically designed activities of daily living (ADL) observations can measure disability due to apraxia with more sensitivity than the Barthel ADL Index, a conventional functional scale. Cross-sectional study. Rehabilitation centres and nursing homes. One hundred and six left hemisphere stroke patients with apraxia, hospitalized in rehabilitation centres and nursing homes. ADL observations, Barthel ADL Index, an apraxia test, Motricity Index, Functional Motor Test. Multivariate analyses showed that the specific ADL observations were associated with severity of apraxia (and not with motor impairments). The Barthel ADL Index was associated with motor impairments (and not with severity of apraxia). The assessment of disability in stroke patients with apraxia cannot rely only on the Barthel ADL Index. In addition, the specific ADL observation procedure is needed to measure disability due to apraxia.

  5. Sensitivity of different ADL measures to apraxia and motor impairments

    NARCIS (Netherlands)

    Donkervoort, M.; Dekker, J.; Deelman, B.G.

    2002-01-01

    Objective: To determine whether specifically designed activities of daily living (ADL) observations can measure disability due to apraxia with more sensitivity than the Barthel ADL Index, a conventional functional scale. Design: Cross-sectional study. Setting: Rehabilitation centres and nursing

  6. Sensitivity of different ADL measures to apraxia and motor impairments

    OpenAIRE

    Donkervoort, M.; Dekker, J.; Deelman, B.G.

    2002-01-01

    Objective: To determine whether specifically designed activities of daily living (ADL) observations can measure disability due to apraxia with more sensitivity than the Barthel ADL Index, a conventional functional scale. Design: Cross-sectional study. Setting: Rehabilitation centres and nursing homes. Subjects: One hundred and six left hemisphere stroke patients with apraxia, hospitalized in rehabilitation centres and nursing homes. Measures: ADL observations, Barthel ADL Index, an apraxia te...

  7. Fluid Ability (Gf and Complex Problem Solving (CPS

    Directory of Open Access Journals (Sweden)

    Patrick Kyllonen

    2017-07-01

    Full Text Available Complex problem solving (CPS has emerged over the past several decades as an important construct in education and in the workforce. We examine the relationship between CPS and general fluid ability (Gf both conceptually and empirically. A review of definitions of the two factors, prototypical tasks, and the information processing analyses of performance on those tasks suggest considerable conceptual overlap. We review three definitions of CPS: a general definition emerging from the human problem solving literature; a more specialized definition from the “German School” emphasizing performance in many-variable microworlds, with high domain-knowledge requirements; and a third definition based on performance in Minimal Complex Systems (MCS, with fewer variables and reduced knowledge requirements. We find a correlation of 0.86 between expert ratings of the importance of CPS and Gf across 691 occupations in the O*NET database. We find evidence that employers value both Gf and CPS skills, but CPS skills more highly, even after controlling for the importance of domain knowledge. We suggest that this may be due to CPS requiring not just cognitive ability but additionally skill in applying that ability in domains. We suggest that a fruitful future direction is to explore the importance of domain knowledge in CPS.

  8. An Operational Foundation for Delimited Continuations in the CPS Hierarchy

    DEFF Research Database (Denmark)

    Biernacka, Malgorzata; Biernacki, Dariusz; Danvy, Olivier

    2004-01-01

    We present an abstract machine and a reduction semantics for the lambda-calculus extended with control operators that give access to delimited continuations in the CPS hierarchy. The abstract machine is derived from an evaluator in continuation-passing style (CPS); the reduction semantics (i.......e., a small-step operational semantics with an explicit representation of evaluation contexts) is constructed from the abstract machine; and the control operators are the shift and reset family. We also present new applications of delimited continuations in the CPS hierarchy: finding list prefixes...

  9. An Operational Foundation for Delimited Continuations in the CPS Hierarchy

    DEFF Research Database (Denmark)

    Biernacka, Malgorzata; Biernacki, Dariusz; Danvy, Olivier

    2005-01-01

    We present an abstract machine and a reduction semantics for the lambda-calculus extended with control operators that give access to delimited continuations in the CPS hierarchy. The abstract machine is derived from an evaluator in continuation-passing style (CPS); the reduction semantics (i.......e., a small-step operational semantics with an explicit representation of evaluation contexts) is constructed from the abstract machine; and the control operators are the shift and reset family. We also present new applications of delimited continuations in the CPS hierarchy: finding list prefixes...

  10. Targeting CPS1 in the treatment of Carbamoyl phosphate synthetase 1 (CPS1) deficiency, a urea cycle disorder.

    Science.gov (United States)

    Diez-Fernandez, Carmen; Häberle, Johannes

    2017-04-01

    Carbamoyl phosphate synthetase 1 (CPS1) deficiency (CPS1D) is a rare autosomal recessive urea cycle disorder (UCD), which can lead to life-threatening hyperammonemia. Unless promptly treated, it can result in encephalopathy, coma and death, or intellectual disability in surviving patients. Over recent decades, therapies for CPS1D have barely improved leaving the management of these patients largely unchanged. Additionally, in many cases, current management (protein-restriction and supplementation with citrulline and/or arginine and ammonia scavengers) is insufficient for achieving metabolic stability, highlighting the importance of developing alternative therapeutic approaches. Areas covered: After describing UCDs and CPS1D, we give an overview of the structure- function of CPS1. We then describe current management and potential novel treatments including N-carbamoyl-L-glutamate (NCG), pharmacological chaperones, and gene therapy to treat hyperammonemia. Expert opinion: Probably, the first novel CPS1D therapies to reach the clinics will be the already commercial substance NCG, which is the standard treatment for N-acetylglutamate synthase deficiency and has been proven to rescue specific CPS1D mutations. Pharmacological chaperones and gene therapy are under development too, but these two technologies still have key challenges to be overcome. In addition, current experimental therapies will hopefully add further treatment options.

  11. A First-Order One-Pass CPS Transformation

    DEFF Research Database (Denmark)

    Danvy, Olivier; Nielsen, Lasse Reichstein

    2002-01-01

    We present a new transformation of call-by-value lambdaterms into continuation-passing style (CPS). This transformation operates in one pass and is both compositional and first-order. Because it operates in one pass, it directly yields compact CPS programs that are comparable to what one would...... write by hand. Because it is compositional, it allows proofs by structural induction. Because it is first-order, reasoning about it does not require the use of a logical relation. This new CPS transformation connects two separate lines of research. It has already been used to state a new and simpler...... correctness proof of a direct-style transformation, and to develop a new and simpler CPS transformation of control-flow information....

  12. Resource-aware control and dynamic scheduling in CPS

    NARCIS (Netherlands)

    Heemels, W.P.M.H.

    2015-01-01

    Recent developments in computer and communication technologies are leading to an increasingly networked and wireless world. This raises new challenging questions in the context of control for cyberphysical systems (CPS), especially when the computation, communication, energy and actuation resources

  13. A hybrid intermediate language between SSA and CPS

    DEFF Research Database (Denmark)

    Torrens, Paulo; Vasconcellos, Cristiano; Gonçalves, Ju

    2017-01-01

    passing style (CPS) lambda calculus has been used as intermediate language for functional language compilers, they are (almost) equivalent and it is possible to draw syntactic translations between them. This short paper aims to present an untyped intermediate language which may be interpreted as both SSA...... and CPS, in order to provide a common language for both imperative and functional compilers, as well to take advantage of optimizations designed for either one of the approaches. Finally, potential variants and research opportunities are discussed....

  14. CPW to CPS transition for feeding UWB antennas

    DEFF Research Database (Denmark)

    Butrym, Alexander; Pivnenko, Sergey

    2004-01-01

    The paper considers a transition (balun) from Coplanar Waveguide (CPW) to Coplanar Stripline (CPS) which is non-resonant and suitable for feeding UWB antennas such as Tapered Slot Antennas (Vivaldi antennas in particular), bow-tie antennas, and other. Some numerical and experimental results...

  15. CPW to CPS transition for feeding UWB antennas

    DEFF Research Database (Denmark)

    Butrym, Alexander; Pivnenko, Sergey

    2006-01-01

    The paper considers a transition (balun) from Coplanar Waveguide (CPW) to Coplanar Stripline (CPS) which is non-resonant and suitable for feeding UWB antennas such as Tapered Slot Antennas (Vivaldi antennas, in particular), bow-tie antennas, and other. Some numerical and experimental results...

  16. CPS Transformation of Flow Information, Part II: Administrative Reductions

    DEFF Research Database (Denmark)

    Damian, Daniel; Danvy, Olivier

    2001-01-01

    the least solution. Preservation of least solutions solves a problem that was left open in Palsberg and Wand's article ‘CPS Transformation of Flow Information.’ Together, Palsberg and Wand's article and the present article show how to map in linear time the least solution of the flow constraints...

  17. [Psychometric properties of the Activities Daily Life Scale (ADL)].

    Science.gov (United States)

    Boyer, L; Murcia, A; Belzeaux, R; Loundou, A; Azorin, J-M; Chabannes, J-M; Dassa, D; Naudin, J; Samuelian, J-C; Lancon, C

    2010-10-01

    Deficits in social functioning are an important core feature of mental health. Recently in France, the Activities Daily Life (ADL) scale has been proposed by the French authorities to assess social functioning for all hospitalized patients in a psychiatric ward. The perspective is to use this scale in the financing and organization of mental health services in France. The ADL scale is a 6-item (dressing/undressing, walking/mobility, eating/drinking, using toilets, behaviour, relationships/communication) heteroquestionnaire completed by a health care professional at the beginning of each hospitalization, assessing functioning of patients suffering from mental health diseases. However, limited consensus exists on this scale. The psychometric properties of the ADL scale have not been assessed. There is a pressing need for detailed examination of its performance. The aim of this study was to explore ADL psychometric properties in a sample of hospitalized patients in a psychiatric ward. We retrospectively analyzed data for all episodes of care delivered to hospitalized patients in a psychiatric ward in our French Public Hospital from January 1, 2008 to June 30, 2008. The study involved retrospective review of administrative and medical databases. The following data were collected: age, gender, diagnoses based on the International Classification of Diseases - 10th version, ADL scale and Assessment of Social Self-Sufficiency scale (ASSS). The psychometric properties were examined using construct validity, reliability, external validity, reproducibility and sensitivity to change. Data analysis was performed using SPSS 15.0 and WINSTEP software. A total of 1066 patients completed the ADL scale. Among them, 49.7% were male, mean age was 36.5 ± 10.8, and 83.5% were single. Schizophrenia, schizotypal and delusional disorders (40.0%), mood disorders (27.9%) and mental and behavioural disorders due to psychoactive substance use (12%) were the most common diagnoses. Factor

  18. Role of Ontologies for CPS Implementation in Manufacturing

    Directory of Open Access Journals (Sweden)

    Garetti Marco

    2015-12-01

    Full Text Available Cyber Physical Systems are an evolution of embedded systems featuring a tight combination of collaborating computational elements that control physical entities. CPSs promise a great potential of innovation in many areas including manufacturing and production. This is because we obtain a very powerful, flexible, modular infrastructure allowing easy (re configurability and fast ramp-up of manufacturing applications by building a manufacturing system with modular mechatronic components (for machining, transportation and storage and embedded intelligence, by integrating them into a system, through a network connection. However, when building such kind of architectures, the way to supply the needed domain knowledge to real manufacturing applications arises as a problem to solve. In fact, a CPS based architecture for manufacturing is made of smart but independent manufacturing components without any knowledge of the role they have to play together in the real world of manufacturing applications. Ontologies can supply such kind of knowledge, playing a very important role in CPS for manufacturing. The paper deals with this intriguing theme, also presenting an implementation of this approach in a research project for the open automation of manufacturing systems, in which the power of CPS is complemented by the support of an ontology of the manufacturing domain.

  19. An Evaluation of ADLs on Modeling Patterns for Software Architecture

    NARCIS (Netherlands)

    Waqas Kamal, Ahmad; Avgeriou, Paris

    2007-01-01

    Architecture patterns provide solutions to recurring design problems at the architecture level. In order to model patterns during software architecture design, one may use a number of existing Architecture Description Languages (ADLs), including the UML, a generic language but also a de facto

  20. Isolation and identification of citrus psorosis virus Egyptian isolate (CPsV-EG).

    Science.gov (United States)

    Ghazal, S A; El-Dougdoug, Kh A; Mousa, A A; Fahmy, H; Sofy, A R

    2008-01-01

    Citrus psorosis ophiovirus (CPsV), is considered to be of the most serious and deter mental virus pathogen's citrus species trees in Egypt. CPsV-EG was isolated from infected citrus grapefruit (C. paradisi Macf.) at Agric. Res. Centre (ARC). The grapefruit which used for CPsV-EG isolate was found to be free from CTV, CEVd and Spiroplasma citri where as gave -ve results with DTBIA, tissue print hybridization and Diene's stain respectively. CPsV-EG was detected on the basis of biological indexing by graft inoculation which gave oak leaf pattern (OLP) on Dweet tangor and serological assay by DAS-ELISA using Mab specific CPsV. CPsV-EG was reacted with variable responses on 16 host plants belonging to 6 families. Only 8 host plants are susceptible and showed visible external symptoms which appeared as local, systemic and local followed by systemic infections. CPsV-EG isolate was transmitted from infected citrus to citrus by syringe and grafting and herbaceous plants by forefinger inoculation and syringe. The woody indicators and rootstocks were differed in response to CPsV-EG isolate which appeared as no-response, response, sensitivity and hypersensitivity. The serological characters represented as the antigenic determinants of CPsV-EG isolate related to monoclonal antibodies specific CPsV strain where as appeared precipitation reaction by DAS-ELISA and DTBIA. The partial fragment of RNA3 (coat protein gene) of CPsV-EG (-1140bp and -571bp) was amplified by reverse transcription-polymerase chain reaction (RT-PCR) from grapefruit tissues using two sets primers specific CPsV (CPV3 and CPV4) and (PS66 and PS65) respectively. The virus under study was identified as CPsV-EG isolate according to biological, serological and molecular characters.

  1. File list: DNS.Adl.05.AllAg.Octopaminergic_neurons [Chip-atlas[Archive

    Lifescience Database Archive (English)

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    Lifescience Database Archive (English)

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  3. File list: Pol.Adl.05.AllAg.Octopaminergic_neurons [Chip-atlas[Archive

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    Lifescience Database Archive (English)

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    Full Text Available Oth.Adl.50.AllAg.Octopaminergic_neurons dm3 TFs and others Adult Octopaminergic neurons... http://dbarchive.biosciencedbc.jp/kyushu-u/dm3/assembled/Oth.Adl.50.AllAg.Octopaminergic_neurons.bed ...

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    Full Text Available DNS.Adl.20.AllAg.Octopaminergic_neurons dm3 DNase-seq Adult Octopaminergic neurons ...http://dbarchive.biosciencedbc.jp/kyushu-u/dm3/assembled/DNS.Adl.20.AllAg.Octopaminergic_neurons.bed ...

  8. File list: DNS.Adl.50.AllAg.Octopaminergic_neurons [Chip-atlas[Archive

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    Full Text Available DNS.Adl.50.AllAg.Octopaminergic_neurons dm3 DNase-seq Adult Octopaminergic neurons ...http://dbarchive.biosciencedbc.jp/kyushu-u/dm3/assembled/DNS.Adl.50.AllAg.Octopaminergic_neurons.bed ...

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  12. File list: Pol.Adl.50.AllAg.Octopaminergic_neurons [Chip-atlas[Archive

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    Full Text Available Pol.Adl.50.AllAg.Octopaminergic_neurons dm3 RNA polymerase Adult Octopaminergic neurons... http://dbarchive.biosciencedbc.jp/kyushu-u/dm3/assembled/Pol.Adl.50.AllAg.Octopaminergic_neurons.bed ...

  13. File list: Oth.Adl.05.AllAg.Octopaminergic_neurons [Chip-atlas[Archive

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    Full Text Available Oth.Adl.05.AllAg.Octopaminergic_neurons dm3 TFs and others Adult Octopaminergic neurons... http://dbarchive.biosciencedbc.jp/kyushu-u/dm3/assembled/Oth.Adl.05.AllAg.Octopaminergic_neurons.bed ...

  14. File list: Pol.Adl.10.AllAg.Octopaminergic_neurons [Chip-atlas[Archive

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    Full Text Available Pol.Adl.10.AllAg.Octopaminergic_neurons dm3 RNA polymerase Adult Octopaminergic neurons... http://dbarchive.biosciencedbc.jp/kyushu-u/dm3/assembled/Pol.Adl.10.AllAg.Octopaminergic_neurons.bed ...

  15. Syntactic accidents in program analysis: on the impact of the CPS transformation

    DEFF Research Database (Denmark)

    Damian, Daniel; Danvy, Olivier

    2003-01-01

    We show that a non-duplicating transformation into Continuation-Passing Style (CPS) has no effect on control-flow analysis, a positive effect on binding-time analysis for traditional partial evaluation, and no effect on binding-time analysis for continuation-based partial evaluation: a monovariant...... control-flow analysis yields equivalent results on a direct-style program and on its CPS counterpart, a monovariant binding-time analysis yields less precise results on a direct-style program than on its CPS counterpart, and an enhanced monovariant binding-time analysis yields equivalent results...... on a direct-style program and on its CPS counterpart. Our proof technique amounts to constructing the CPS counterpart of flow information and of binding times. Our results formalize and confirm a folklore theorem about traditional binding-time analysis, namely that CPS has a positive effect on binding times...

  16. Syntactic Accidents in Program Analysis: On the Impact of the CPS Transformation

    DEFF Research Database (Denmark)

    Daniel, Damian; Danvy, Olivier

    2000-01-01

    We show that a non-duplicating transformation into Continuation-Passing Style (CPS) has no effect on control-flow analysis, a positive effect on binding-time analysis for traditional partial evaluation, and no effect on binding-time analysis for continuation-based partial evaluation: a monovariant...... control-flow analysis yields equivalent results on a direct-style program and on its CPS counterpart, a monovariant binding-time analysis yields less precise results on a direct-style program than on its CPS counterpart, and an enhanced monovariant binding-time analysis yields equivalent results...... on a direct-style program and on its CPS counterpart. Our proof technique amounts to constructing the CPS counterpart of flow information and of binding times. Our results formalize and confirm a folklore theorem about traditional binding-time analysis, namely that CPS has a positive effect on binding times...

  17. Self-reported and Observed Quality of ADL Task Performance in Adults with Depression

    DEFF Research Database (Denmark)

    Nielsen, Kristina Tomra; Wæhrens, Eva

    diagnosed with depression (range 19-79, median 45,5) Procedure In order to evaluate the participants’ self-reported and observed quality of ADL task performance the ADL-Interview (ADL-I) and the Assessment of Motor and Process Skills (AMPS) were chosen. Both instruments are developed to evaluate and measure...... the quality of ADL task performance. The ADL-I was conducted first and thereby formed the basis for identifying relevant tasks for the AMPS evaluation. Both evaluations were conducted on the same day by trained and calibrated occupational therapists. Results The results indicated that the participants both...

  18. The tool in the brain: Apraxia in ADL.

    Directory of Open Access Journals (Sweden)

    Marta M. N. Bienkiewicz

    2014-04-01

    Full Text Available Humans differ from other animals in the way they can skilfully and precisely operate or invent tools to facilitate their everyday life. Tools have dominated our home, travel and work environment, becoming an integral step for our motor skills development. What happens when the part of the brain responsible for tool use is damaged in our adult life due to a cerebrovascular accident? How does daily life change when we lose the previously mastered ability to make use of the objects around us? How do patients suffering from compromised tool use cope with food preparation, personal hygiene, grooming, housework or use of home appliances? In this literature review we present a state of the art for single and multiple tool use research, with a focus on the impact that apraxia (impaired ability to perform tool-based actions and action disorganisation syndrome (impaired ability to carry our multi-step actions have on activities of daily living (ADL. Firstly, we summarise the behavioural studies investigating the impact of apraxia and other comorbidity syndromes, such as neglect or visual extinction, on ADL. We discuss the hallmarks of the compromised tool use in terms of the sequencing of action steps, conceptual errors committed, spatial motor control and temporal organisation of the movement. In addition, we present an up-to-date overview of the neuroimaging and lesion analyses studies that provide an insight into neural correlates of tool use in the human brain and functional changes in the neural organisation following a stroke, in the context of ADL. Finally we discuss the current practice in neurorehabilitation of ADL in apraxia and action disorganisation syndrome aiming at increasing patients’ independence.

  19. Advancements in Distributed Learning (ADL) Environment in Support of Transformation

    Science.gov (United States)

    2017-01-01

    take a variety of forms, including Task Groups, Workshops, Symposia, Specialists’ Meetings, Lecture Series and Technical Courses . The content of this... MySQL and PHP Apache xAPI Extensive Application Program Interface viii STO-TR-HFM-212 HFM-212 Membership List Dr. Oleksandr BUROV Institute...in Paris, France, initiated a new management infrastructure for collaboration and integration of learning courses and technologies. This ADL effort

  20. Physical performance as long-term predictor of onset of activities of daily living (ADL) disability

    DEFF Research Database (Denmark)

    Idland, Gro; Pettersen, Renate; Avlund, Kirsten

    2013-01-01

    non-disabled community-dwelling women with a mean age of 79.5 years at baseline. The baseline examinations of physical performance were: functional reach, climbing steps and comfortable walking speed. ADL disability was defined as need of personal assistance in at least one of five basic ADL items......Disability in ADL of aging women is an important public health concern. It is thus of interest to identify modifiable factors underlying onset of ADL disability. We assessed whether three physical performance-based measurements could predict ADL disability 9 years later. The participants were 113....... The participants were followed for 9 years. Logistic regression models were fitted for each of the physical performance measurements together with the covariates in relation to ADL disability. At follow-up 25.7% were disabled in ADL. All three performance measurements were significantly associated with the onset...

  1. The Classroom Process Scale (CPS): An Approach to the Measurement of Teaching Effectiveness.

    Science.gov (United States)

    Anderson, Lorin W.; Scott, Corinne C.

    The purpose of this presentation is to describe the Classroom Process Scale (CPS) and its usefulness for the assessment of teaching effectiveness. The CPS attempts to ameliorate weaknesses in existing classroom process measures by including a coding of student involvement in learning, objectives being pursued, and methods used to pursue attainment…

  2. MMI design of K-CPS for preventing human errors and enhancing convenient operation

    International Nuclear Information System (INIS)

    Sung, Chan Ho; Jung, Yeon Sub; Oh, Eoung Se; Shin, Young Chul; Lee, Yong Kwan

    2001-01-01

    In order to supplement defects of paper procedure, reduce human errors and enhance convenient operation, computer-based procedure system is being developed. CPS (Computerized Procedure System) including human-factor engineering design concept for KNGR (Korean Next Generation Reactor) has been also developed with the same object. K-CPS(KNGR CPS) has higher level of automation than paper procedure. It is fully integrated with control and monitoring systems. Combining statements and relevant components, which changes dynamically according to plant status enhances readability of procedure. This paper shows general design criteria on computer-based procedure system, the MMI design characteristics of K-CPS and the results of suitability evaluation for K-CPS by operator

  3. Phylogenetic distribution and membrane topology of the LytR-CpsA-Psr protein family

    Directory of Open Access Journals (Sweden)

    Berger-Bächi Brigitte

    2008-12-01

    Full Text Available Abstract Background The bacterial cell wall is the target of many antibiotics and cell envelope constituents are critical to host-pathogen interactions. To combat resistance development and virulence, a detailed knowledge of the individual factors involved is essential. Members of the LytR-CpsA-Psr family of cell envelope-associated attenuators are relevant for β-lactam resistance, biofilm formation, and stress tolerance, and they are suggested to play a role in cell wall maintenance. However, their precise function is still unknown. This study addresses the occurrence as well as sequence-based characteristics of the LytR-CpsA-Psr proteins. Results A comprehensive list of LytR-CpsA-Psr proteins was established, and their phylogenetic distribution and clustering into subgroups was determined. LytR-CpsA-Psr proteins were present in all Gram-positive organisms, except for the cell wall-deficient Mollicutes and one strain of the Clostridiales. In contrast, the majority of Gram-negatives did not contain LytR-CpsA-Psr family members. Despite high sequence divergence, the LytR-CpsA-Psr domains of different subclusters shared a highly similar, predicted mixed a/β-structure, and conserved charged residues. PhoA fusion experiments, using MsrR of Staphylococcus aureus, confirmed membrane topology predictions and extracellular location of its LytR-CpsA-Psr domain. Conclusion The LytR-CpsA-Psr domain is unique to bacteria. The presence of diverse subgroups within the LytR-CpsA-Psr family might indicate functional differences, and could explain variations in phenotypes of respective mutants reported. The identified conserved structural elements and amino acids are likely to be important for the function of the domain and will help to guide future studies of the LytR-CpsA-Psr proteins.

  4. Self-reported quality of ADL task performance among patients with COPD exacerbations.

    Science.gov (United States)

    Bendixen, Hans Jørgen; Wæhrens, Eva Ejlersen; Wilcke, Jon Torgny; Sørensen, Lisbeth Villemoes

    2014-07-01

    Patients suffering from chronic obstructive pulmonary disease (COPD) experience problems in the performance of activities of daily living (ADL) tasks. The objective was to examine the self-reported quality of ADL task performance among COPD patients, and to investigate whether age, gender, and routine COPD characteristics correlate with the self-reported ADL ability. Eighty patients admitted to hospital with COPD exacerbations participated. In a cross-sectional study, the patients' self-reported ADL ability was assessed using the ADL-Interview (ADL-I) instrument. Data concerning age, gender, and routine COPD characteristics were drawn from the patients' medical records. The patients reported being inefficient to markedly inefficient when performing ADL tasks within the personal hygiene, toileting, dressing, household, mobility, and transportation domains. While more than 90% of the participants reported increased effort and/or fatigue when performing the ADL tasks, up to 88% of the participants relied on help from others in the performance of general household chores like cooking and shopping. Self-reported ADL ability did not correlate with age, gender, or routine COPD characteristics. Decreased quality of ADL task performance seemed to be extremely common among COPD patients. Therefore, addressing the problems in individually tailored pulmonary rehabilitation programmes may be advantageous.

  5. Muscle strength as a predictor of onset of ADL dependence in people aged 75 years

    DEFF Research Database (Denmark)

    Rantanen, Taina; Avlund, Kirsten; Suominen, Harri

    2002-01-01

    . For each muscle group tested, three equal groups were formed for men and women separately based on distributions of results. Those who reported being unable or needing help for eating, dressing, bathing, toileting, walking indoors or transferring from a bed or a chair were rated as ADL dependent....... Of the 227 initially ADL independent men, 21 (9.3%) became dependent in ADL. In women, the figures were 30 (8.8%) of 340. Multiple logistic regression models were used to predict the risk of ADL dependence in groups based on strength tertiles. After confirming that the association of muscle strength...... and incident ADL-dependence was similar in men and women, both genders were included in the same analyses adjusted for body weight and height, gender and research locality. Gender specific cut-offs were used for strength tertiles. All the strength tests predicted ADL dependence, with those being in the lowest...

  6. Validity and reliability of the Arabic version of Activities of Daily Living (ADL

    Directory of Open Access Journals (Sweden)

    Doumit Jacqueline

    2009-03-01

    Full Text Available Abstract Background The Activity of Daily Living (ADL is an instrument that screens elderly respondents for physical functioning and assesses whether they are dependent or independent in their daily activities. This study demonstrates a translation procedure and obtains the reliability and validity of a translated, Arabic ADL. Methods The ADL was translated to Arabic through a forward translation method followed by a committee-consensual approach. The ADL and the Arabic Mini-Mental State Examination (AMMSE were administered to an opportunistic sample of 354 Lebanese elderly living in nursing homes who did not have dementia. Results Reliability split half measures, sensitivity, and negative predictive values were high across all dimensions of the ADL with the exception of feeding. There were non-significant differences on the scored ADL between the three age groups: young age, middle age and older old. In addition, a non-significant difference was found on the scored ADL between the high and low AMMSE scores. Conclusion Overall, the translated ADL was consistent and valid measure for assessing daily activities in elderly nursing home residents. As it is quick and easy to use, the ADL in Arabic could help caregivers and doctors to prescribe appropriate physical exercise for elderly Arabic speaking patients.

  7. Alternate Communications Spectrum Study (ACSS) for Aviation Data Links (ADL)

    Science.gov (United States)

    Matolak, David W.

    2003-01-01

    The aim of the work was to identify the key factors involved in the use of alternate spectrum in various bands for a future integrated CNS data link. The study focused on systems and spectral bands that can deliver VDL-or-higher data rates in a two-way communication setting (including air-ground, ground-air, and air-air modes of operation), with multiple platforms (aircraft) operating in the same local environment. We begin with a review of the initial task list, and the final task list. The final task list contained a focus upon spectral availability and related systems that could be affected by the deployment of a new aviation data link (ADL) system. Most of this addresses the lower few layers of the communications protocol stack. A brief review of current related efforts in the aeronautical community is then provided, in which we describe several systems and programs of interest. Participation in some of these efforts is recommended. We also delineate several of the advantages and disadvantages of these system/efforts, in view of anticipated requirements of a new ADL. Desired attributes of a new ADL system are then discussed, and a connection with existing systems is made. The need to consider a wider set of alternative systems and technologies is described, and the beneficial aspects of a particular transmission technique- spread spectrum-are discussed. We then discuss in more detail several potential spectral regions, in terms of propagation conditions, available technology, spectrum availability, and waveform selection. Some comments on the need for standardization are also provided. We note that none of the existing systems described will likely meet the full range of desired features of a new ADL, but that several systems and spectral regions offer promise in terms of one or more characteristics. A system design and analysis approach is then provided. In this, we again focus on the lower few layers of the protocol stack, and aim to capture the main features

  8. Differences between questionnaire-and interview-based measures of activities of daily living (ADL) ability and their association with observed ADL ability in women with rheumatoid arthritis, knee osteoarthritis, and fibromyalgia

    DEFF Research Database (Denmark)

    Wæhrens, E. E.; Bliddal, Henning; Danneskiold-Samsøe, Bente

    2012-01-01

    Objectives: Although self-report based on questionnaire is the common method to obtain information about activities of daily living (ADL) ability in rheumatic diseases, little is known about the relationship between measures of ADL ability based on questionnaire, interview, and observation. The p...... of self-reported ADL ability based on either questionnaire or interview have limited relationship to each other or to observed performance of ADL tasks....... the relationships between self-reported and observed ADL ability. Method: The 47 ADL tasks of the ADL taxonomy were used to evaluate self-reported ADL ability based on questionnaire (ADL-Q) and interview (ADL-I), and the Assessment of Motor and Process Skills (AMPS) was used to obtain measures of observed ADL......Objectives: Although self-report based on questionnaire is the common method to obtain information about activities of daily living (ADL) ability in rheumatic diseases, little is known about the relationship between measures of ADL ability based on questionnaire, interview, and observation...

  9. SVM-Based Dynamic Reconfiguration CPS for Manufacturing System in Industry 4.0

    Directory of Open Access Journals (Sweden)

    Hyun-Jun Shin

    2018-01-01

    Full Text Available CPS is potential application in various fields, such as medical, healthcare, energy, transportation, and defense, as well as Industry 4.0 in Germany. Although studies on the equipment aging and prediction of problem have been done by combining CPS with Industry 4.0, such studies were based on small numbers and majority of the papers focused primarily on CPS methodology. Therefore, it is necessary to study active self-protection to enable self-management functions, such as self-healing by applying CPS in shop-floor. In this paper, we have proposed modeling of shop-floor and a dynamic reconfigurable CPS scheme that can predict the occurrence of anomalies and self-protection in the model. For this purpose, SVM was used as a machine learning technology and it was possible to restrain overloading in manufacturing process. In addition, we design CPS framework based on machine learning for Industry 4.0, simulate it, and perform. Simulation results show the simulation model autonomously detects the abnormal situation and it is dynamically reconfigured through self-healing.

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  3. File list: Pol.Adl.05.RNA_polymerase_III.AllCell [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available Pol.Adl.05.RNA_polymerase_III.AllCell ce10 RNA polymerase RNA polymerase III Adult ...SRX395531,SRX331268,SRX331270,SRX395532 http://dbarchive.biosciencedbc.jp/kyushu-u/ce10/assembled/Pol.Adl.05.RNA_polymerase_III.AllCell.bed ...

  4. File list: Pol.Adl.05.RNA_Polymerase_II.AllCell [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available Pol.Adl.05.RNA_Polymerase_II.AllCell ce10 RNA polymerase RNA Polymerase II Adult SR...SRX1388757,SRX1388756 http://dbarchive.biosciencedbc.jp/kyushu-u/ce10/assembled/Pol.Adl.05.RNA_Polymerase_II.AllCell.bed ...

  5. File list: Pol.Adl.50.RNA_polymerase_II.AllCell [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available Pol.Adl.50.RNA_polymerase_II.AllCell ce10 RNA polymerase RNA polymerase II Adult SR...SRX043965,SRX005629,SRX043964,SRX554718 http://dbarchive.biosciencedbc.jp/kyushu-u/ce10/assembled/Pol.Adl.50.RNA_polymerase_II.AllCell.bed ...

  6. File list: Pol.Adl.20.RNA_polymerase_II.AllCell [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available Pol.Adl.20.RNA_polymerase_II.AllCell ce10 RNA polymerase RNA polymerase II Adult SR...SRX554718,SRX043965,SRX043963,SRX043964 http://dbarchive.biosciencedbc.jp/kyushu-u/ce10/assembled/Pol.Adl.20.RNA_polymerase_II.AllCell.bed ...

  7. File list: InP.Adl.05.AllAg.Young_adult [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available InP.Adl.05.AllAg.Young_adult ce10 Input control Adult Young adult SRX005630,SRX4670...9,SRX005633 http://dbarchive.biosciencedbc.jp/kyushu-u/ce10/assembled/InP.Adl.05.AllAg.Young_adult.bed ...

  8. File list: ALL.Adl.20.AllAg.Young_adult [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available ALL.Adl.20.AllAg.Young_adult ce10 All antigens Adult Young adult SRX331330,SRX14642...4210 http://dbarchive.biosciencedbc.jp/kyushu-u/ce10/assembled/ALL.Adl.20.AllAg.Young_adult.bed ...

  9. File list: Pol.Adl.05.AllAg.Young_adult [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available Pol.Adl.05.AllAg.Young_adult ce10 RNA polymerase Adult Young adult SRX395531,SRX331...RX043965 http://dbarchive.biosciencedbc.jp/kyushu-u/ce10/assembled/Pol.Adl.05.AllAg.Young_adult.bed ...

  10. File list: ALL.Adl.05.AllAg.Young_adult [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available ALL.Adl.05.AllAg.Young_adult ce10 All antigens Adult Young adult SRX080072,SRX39553...2299,SRX005633 http://dbarchive.biosciencedbc.jp/kyushu-u/ce10/assembled/ALL.Adl.05.AllAg.Young_adult.bed ...

  11. File list: His.Adl.50.AllAg.Young_adult [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available His.Adl.50.AllAg.Young_adult ce10 Histone Adult Young adult SRX1388777,SRX554723,SR...1388779,SRX1388772,SRX1388771,SRX1388778,SRX012297 http://dbarchive.biosciencedbc.jp/kyushu-u/ce10/assembled/His.Adl.50.AllAg.Young_adult.bed ...

  12. File list: Pol.Adl.10.AllAg.Young_adult [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available Pol.Adl.10.AllAg.Young_adult ce10 RNA polymerase Adult Young adult SRX395531,SRX331...RX043965 http://dbarchive.biosciencedbc.jp/kyushu-u/ce10/assembled/Pol.Adl.10.AllAg.Young_adult.bed ...

  13. File list: InP.Adl.50.AllAg.Young_adult [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available InP.Adl.50.AllAg.Young_adult ce10 Input control Adult Young adult SRX005630,SRX3732...X331269,SRX331331,SRX467093,SRX982096,SRX1388752,SRX1388749,SRX235166,SRX012299 http://dbarchive.biosciencedbc.jp/kyushu-u/ce10/assembled/InP.Adl.50.AllAg.Young_adult.bed ...

  14. File list: Unc.Adl.20.AllAg.Young_adult [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available Unc.Adl.20.AllAg.Young_adult ce10 Unclassified Adult Young adult SRX707297,SRX70729...8 http://dbarchive.biosciencedbc.jp/kyushu-u/ce10/assembled/Unc.Adl.20.AllAg.Young_adult.bed ...

  15. File list: Unc.Adl.05.AllAg.Young_adult [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available Unc.Adl.05.AllAg.Young_adult ce10 Unclassified Adult Young adult SRX707297,SRX70729...8 http://dbarchive.biosciencedbc.jp/kyushu-u/ce10/assembled/Unc.Adl.05.AllAg.Young_adult.bed ...

  16. File list: Pol.Adl.20.AllAg.Young_adult [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available Pol.Adl.20.AllAg.Young_adult ce10 RNA polymerase Adult Young adult SRX331268,SRX331...RX043964 http://dbarchive.biosciencedbc.jp/kyushu-u/ce10/assembled/Pol.Adl.20.AllAg.Young_adult.bed ...

  17. File list: ALL.Adl.10.AllAg.Young_adult [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available ALL.Adl.10.AllAg.Young_adult ce10 All antigens Adult Young adult SRX395531,SRX08007...4210,SRX005633 http://dbarchive.biosciencedbc.jp/kyushu-u/ce10/assembled/ALL.Adl.10.AllAg.Young_adult.bed ...

  18. File list: ALL.Adl.50.AllAg.Young_adult [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available ALL.Adl.50.AllAg.Young_adult ce10 All antigens Adult Young adult SRX331330,SRX14642...54208,SRX054210,SRX054211 http://dbarchive.biosciencedbc.jp/kyushu-u/ce10/assembled/ALL.Adl.50.AllAg.Young_adult.bed ...

  19. File list: His.Adl.05.AllAg.Young_adult [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available His.Adl.05.AllAg.Young_adult ce10 Histone Adult Young adult SRX554723,SRX1388779,SR...RX1388775,SRX554734,SRX1388768,SRX012297,SRX012298,SRX012300 http://dbarchive.biosciencedbc.jp/kyushu-u/ce10/assembled/His.Adl.05.AllAg.Young_adult.bed ...

  20. File list: His.Adl.10.AllAg.Young_adult [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available His.Adl.10.AllAg.Young_adult ce10 Histone Adult Young adult SRX1388777,SRX1388779,S...SRX554724,SRX554734,SRX1388769,SRX012297,SRX012298,SRX012300 http://dbarchive.biosciencedbc.jp/kyushu-u/ce10/assembled/His.Adl.10.AllAg.Young_adult.bed ...

  1. File list: Oth.Adl.50.AllAg.Young_adult [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available Oth.Adl.50.AllAg.Young_adult ce10 TFs and others Adult Young adult SRX331330,SRX146...,SRX054211 http://dbarchive.biosciencedbc.jp/kyushu-u/ce10/assembled/Oth.Adl.50.AllAg.Young_adult.bed ...

  2. File list: InP.Adl.10.AllAg.Young_adult [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available InP.Adl.10.AllAg.Young_adult ce10 Input control Adult Young adult SRX005630,SRX0056...6,SRX005633 http://dbarchive.biosciencedbc.jp/kyushu-u/ce10/assembled/InP.Adl.10.AllAg.Young_adult.bed ...

  3. File list: Oth.Adl.10.AllAg.Young_adult [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available Oth.Adl.10.AllAg.Young_adult ce10 TFs and others Adult Young adult SRX080072,SRX331...,SRX054211,SRX054210 http://dbarchive.biosciencedbc.jp/kyushu-u/ce10/assembled/Oth.Adl.10.AllAg.Young_adult.bed ...

  4. File list: Oth.Adl.20.AllAg.Young_adult [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available Oth.Adl.20.AllAg.Young_adult ce10 TFs and others Adult Young adult SRX331330,SRX146...,SRX054208,SRX054210 http://dbarchive.biosciencedbc.jp/kyushu-u/ce10/assembled/Oth.Adl.20.AllAg.Young_adult.bed ...

  5. File list: InP.Adl.50.AllAg.Ovary [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available InP.Adl.50.AllAg.Ovary dm3 Input control Adult Ovary SRX264598,SRX1120694,SRX507393...215629,SRX507394,SRX215627,SRX215623,SRX215625,SRX507386 http://dbarchive.biosciencedbc.jp/kyushu-u/dm3/assembled/InP.Adl.50.AllAg.Ovary.bed ...

  6. File list: His.Adl.20.AllAg.Egg_chamber [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available His.Adl.20.AllAg.Egg_chamber dm3 Histone Adult Egg chamber SRX914961,SRX914956,SRX9...14959,SRX914952,SRX914963,SRX914962,SRX914960,SRX914958,SRX914966,SRX914964,SRX914954 http://dbarchive.biosciencedbc.jp/kyushu-u/dm3/assembled/His.Adl.20.AllAg.Egg_chamber.bed ...

  7. File list: Oth.Adl.50.AllAg.Egg_chamber [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available Oth.Adl.50.AllAg.Egg_chamber dm3 TFs and others Adult Egg chamber SRX706815,SRX7068...11,SRX706814,SRX706810 http://dbarchive.biosciencedbc.jp/kyushu-u/dm3/assembled/Oth.Adl.50.AllAg.Egg_chamber.bed ...

  8. File list: InP.Adl.20.AllAg.Egg_chamber [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available InP.Adl.20.AllAg.Egg_chamber dm3 Input control Adult Egg chamber SRX706813,SRX70681...2,SRX706816 http://dbarchive.biosciencedbc.jp/kyushu-u/dm3/assembled/InP.Adl.20.AllAg.Egg_chamber.bed ...

  9. File list: Oth.Adl.05.AllAg.Egg_chamber [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available Oth.Adl.05.AllAg.Egg_chamber dm3 TFs and others Adult Egg chamber SRX706810,SRX7068...14,SRX706815,SRX706811 http://dbarchive.biosciencedbc.jp/kyushu-u/dm3/assembled/Oth.Adl.05.AllAg.Egg_chamber.bed ...

  10. File list: InP.Adl.50.AllAg.Egg_chamber [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available InP.Adl.50.AllAg.Egg_chamber dm3 Input control Adult Egg chamber SRX706812,SRX70681...6,SRX706813 http://dbarchive.biosciencedbc.jp/kyushu-u/dm3/assembled/InP.Adl.50.AllAg.Egg_chamber.bed ...

  11. File list: ALL.Adl.10.AllAg.Egg_chamber [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available ALL.Adl.10.AllAg.Egg_chamber dm3 All antigens Adult Egg chamber SRX914951,SRX914955...58,SRX706813,SRX706815,SRX914957,SRX706816,SRX914964,SRX706811,SRX914966,SRX914954,SRX706812 http://dbarchive.biosciencedbc.jp/kyushu-u/dm3/assembled/ALL.Adl.10.AllAg.Egg_chamber.bed ...

  12. File list: ALL.Adl.20.AllAg.Egg_chamber [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available ALL.Adl.20.AllAg.Egg_chamber dm3 All antigens Adult Egg chamber SRX914951,SRX914955...13,SRX914958,SRX914966,SRX914964,SRX706811,SRX914954,SRX706815,SRX706812,SRX706816,SRX706810 http://dbarchive.biosciencedbc.jp/kyushu-u/dm3/assembled/ALL.Adl.20.AllAg.Egg_chamber.bed ...

  13. File list: InP.Adl.05.AllAg.Egg_chamber [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available InP.Adl.05.AllAg.Egg_chamber dm3 Input control Adult Egg chamber SRX706813,SRX70681...2,SRX706816 http://dbarchive.biosciencedbc.jp/kyushu-u/dm3/assembled/InP.Adl.05.AllAg.Egg_chamber.bed ...

  14. File list: Oth.Adl.10.AllAg.Egg_chamber [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available Oth.Adl.10.AllAg.Egg_chamber dm3 TFs and others Adult Egg chamber SRX706814,SRX7068...10,SRX706815,SRX706811 http://dbarchive.biosciencedbc.jp/kyushu-u/dm3/assembled/Oth.Adl.10.AllAg.Egg_chamber.bed ...

  15. File list: Unc.Adl.10.AllAg.Egg_chamber [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available Unc.Adl.10.AllAg.Egg_chamber dm3 Unclassified Adult Egg chamber SRX914951,SRX914955...,SRX914953,SRX914957 http://dbarchive.biosciencedbc.jp/kyushu-u/dm3/assembled/Unc.Adl.10.AllAg.Egg_chamber.bed ...

  16. File list: Unc.Adl.50.AllAg.Egg_chamber [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available Unc.Adl.50.AllAg.Egg_chamber dm3 Unclassified Adult Egg chamber SRX914955,SRX914951...,SRX914953 http://dbarchive.biosciencedbc.jp/kyushu-u/dm3/assembled/Unc.Adl.50.AllAg.Egg_chamber.bed ...

  17. File list: His.Adl.10.AllAg.Egg_chamber [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available His.Adl.10.AllAg.Egg_chamber dm3 Histone Adult Egg chamber SRX914961,SRX914952,SRX9...14956,SRX914959,SRX914960,SRX914963,SRX914962,SRX914958,SRX914964,SRX914966,SRX914954 http://dbarchive.biosciencedbc.jp/kyushu-u/dm3/assembled/His.Adl.10.AllAg.Egg_chamber.bed ...

  18. File list: ALL.Adl.50.AllAg.Egg_chamber [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available ALL.Adl.50.AllAg.Egg_chamber dm3 All antigens Adult Egg chamber SRX914955,SRX914951...16,SRX914954,SRX914966,SRX706813,SRX914963,SRX914959,SRX706814,SRX706810,SRX914953 http://dbarchive.biosciencedbc.jp/kyushu-u/dm3/assembled/ALL.Adl.50.AllAg.Egg_chamber.bed ...

  19. File list: Oth.Adl.20.AllAg.Egg_chamber [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available Oth.Adl.20.AllAg.Egg_chamber dm3 TFs and others Adult Egg chamber SRX706814,SRX7068...11,SRX706815,SRX706810 http://dbarchive.biosciencedbc.jp/kyushu-u/dm3/assembled/Oth.Adl.20.AllAg.Egg_chamber.bed ...

  20. File list: Unc.Adl.05.AllAg.Egg_chamber [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available Unc.Adl.05.AllAg.Egg_chamber dm3 Unclassified Adult Egg chamber SRX914955,SRX914951...,SRX914953,SRX914957 http://dbarchive.biosciencedbc.jp/kyushu-u/dm3/assembled/Unc.Adl.05.AllAg.Egg_chamber.bed ...

  1. File list: His.Adl.50.AllAg.Egg_chamber [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available His.Adl.50.AllAg.Egg_chamber dm3 Histone Adult Egg chamber SRX914961,SRX914956,SRX9...14962,SRX914952,SRX914960,SRX914958,SRX914964,SRX914954,SRX914966,SRX914963,SRX914959 http://dbarchive.biosciencedbc.jp/kyushu-u/dm3/assembled/His.Adl.50.AllAg.Egg_chamber.bed ...

  2. File list: Unc.Adl.20.AllAg.Egg_chamber [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available Unc.Adl.20.AllAg.Egg_chamber dm3 Unclassified Adult Egg chamber SRX914951,SRX914955...,SRX914953,SRX914957 http://dbarchive.biosciencedbc.jp/kyushu-u/dm3/assembled/Unc.Adl.20.AllAg.Egg_chamber.bed ...

  3. File list: InP.Adl.10.AllAg.Egg_chamber [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available InP.Adl.10.AllAg.Egg_chamber dm3 Input control Adult Egg chamber SRX706813,SRX70681...6,SRX706812 http://dbarchive.biosciencedbc.jp/kyushu-u/dm3/assembled/InP.Adl.10.AllAg.Egg_chamber.bed ...

  4. File list: Pol.Adl.10.RNA_polymerase_III.AllCell [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available Pol.Adl.10.RNA_polymerase_III.AllCell ce10 RNA polymerase RNA polymerase III Adult ...SRX395531,SRX331268,SRX331270,SRX395532 http://dbarchive.biosciencedbc.jp/kyushu-u/ce10/assembled/Pol.Adl.10.RNA_polymerase_III.AllCell.bed ...

  5. File list: Pol.Adl.50.RNA_polymerase_III.AllCell [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available Pol.Adl.50.RNA_polymerase_III.AllCell ce10 RNA polymerase RNA polymerase III Adult ...SRX331268,SRX331270,SRX395531 http://dbarchive.biosciencedbc.jp/kyushu-u/ce10/assembled/Pol.Adl.50.RNA_polymerase_III.AllCell.bed ...

  6. File list: Unc.Adl.20.AllAg.Adult_female [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available Unc.Adl.20.AllAg.Adult_female dm3 Unclassified Adult Adult female SRX042248,SRX0130...18,SRX032119,SRX013048 http://dbarchive.biosciencedbc.jp/kyushu-u/dm3/assembled/Unc.Adl.20.AllAg.Adult_female.bed ...

  7. File list: His.Adl.05.AllAg.Adult_male [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available His.Adl.05.AllAg.Adult_male dm3 Histone Adult Adult male SRX013084,SRX013033,SRX013...032,SRX013013 http://dbarchive.biosciencedbc.jp/kyushu-u/dm3/assembled/His.Adl.05.AllAg.Adult_male.bed ...

  8. File list: ALL.Adl.20.AllAg.Adult_male [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available ALL.Adl.20.AllAg.Adult_male dm3 All antigens Adult Adult male SRX013049,SRX013050,S...RX013084,SRX013033,SRX013032,SRX013013 http://dbarchive.biosciencedbc.jp/kyushu-u/dm3/assembled/ALL.Adl.20.AllAg.Adult_male.bed ...

  9. File list: His.Adl.50.AllAg.Adult_female [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available His.Adl.50.AllAg.Adult_female dm3 Histone Adult Adult female SRX013017,SRX013034,SR...X013111,SRX013105 http://dbarchive.biosciencedbc.jp/kyushu-u/dm3/assembled/His.Adl.50.AllAg.Adult_female.bed ...

  10. File list: Oth.Adl.50.AllAg.Adult_female [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available Oth.Adl.50.AllAg.Adult_female dm3 TFs and others Adult Adult female SRX1084165,SRX0...25476,SRX041381,SRX032118,SRX013047,SRX016140 http://dbarchive.biosciencedbc.jp/kyushu-u/dm3/assembled/Oth.Adl.50.AllAg.Adult_female.bed ...

  11. File list: His.Adl.05.AllAg.Adult_female [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available His.Adl.05.AllAg.Adult_female dm3 Histone Adult Adult female SRX013017,SRX013034,SR...X013105,SRX013111 http://dbarchive.biosciencedbc.jp/kyushu-u/dm3/assembled/His.Adl.05.AllAg.Adult_female.bed ...

  12. File list: Oth.Adl.20.AllAg.Adult_male_fatbody [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available Oth.Adl.20.AllAg.Adult_male_fatbody dm3 TFs and others Adult Adult male fatbody htt...p://dbarchive.biosciencedbc.jp/kyushu-u/dm3/assembled/Oth.Adl.20.AllAg.Adult_male_fatbody.bed ...

  13. File list: Unc.Adl.10.AllAg.Adult_male_fatbody [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available Unc.Adl.10.AllAg.Adult_male_fatbody dm3 Unclassified Adult Adult male fatbody SRX04...2251,SRX042245,SRX042250 http://dbarchive.biosciencedbc.jp/kyushu-u/dm3/assembled/Unc.Adl.10.AllAg.Adult_male_fatbody.bed ...

  14. File list: Unc.Adl.05.AllAg.Adult_male_fatbody [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available Unc.Adl.05.AllAg.Adult_male_fatbody dm3 Unclassified Adult Adult male fatbody SRX04...2245,SRX042251,SRX042250 http://dbarchive.biosciencedbc.jp/kyushu-u/dm3/assembled/Unc.Adl.05.AllAg.Adult_male_fatbody.bed ...

  15. File list: ALL.Adl.20.AllAg.Adult_male_fatbody [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available ALL.Adl.20.AllAg.Adult_male_fatbody dm3 All antigens Adult Adult male fatbody SRX04...2251,SRX042245,SRX042250 http://dbarchive.biosciencedbc.jp/kyushu-u/dm3/assembled/ALL.Adl.20.AllAg.Adult_male_fatbody.bed ...

  16. File list: Pol.Adl.50.AllAg.Adult_male_fatbody [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available Pol.Adl.50.AllAg.Adult_male_fatbody dm3 RNA polymerase Adult Adult male fatbody htt...p://dbarchive.biosciencedbc.jp/kyushu-u/dm3/assembled/Pol.Adl.50.AllAg.Adult_male_fatbody.bed ...

  17. File list: His.Adl.20.AllAg.Adult_female [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available His.Adl.20.AllAg.Adult_female dm3 Histone Adult Adult female SRX013017,SRX013034,SR...X013105,SRX013111 http://dbarchive.biosciencedbc.jp/kyushu-u/dm3/assembled/His.Adl.20.AllAg.Adult_female.bed ...

  18. File list: His.Adl.10.AllAg.Adult_female [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available His.Adl.10.AllAg.Adult_female dm3 Histone Adult Adult female SRX013017,SRX013034,SR...X013105,SRX013111 http://dbarchive.biosciencedbc.jp/kyushu-u/dm3/assembled/His.Adl.10.AllAg.Adult_female.bed ...

  19. File list: Pol.Adl.10.AllAg.Adult_male_fatbody [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available Pol.Adl.10.AllAg.Adult_male_fatbody dm3 RNA polymerase Adult Adult male fatbody htt...p://dbarchive.biosciencedbc.jp/kyushu-u/dm3/assembled/Pol.Adl.10.AllAg.Adult_male_fatbody.bed ...

  20. File list: ALL.Adl.20.AllAg.Adult_female [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available ALL.Adl.20.AllAg.Adult_female dm3 All antigens Adult Adult female SRX1084165,SRX013...13048,SRX013105,SRX013111 http://dbarchive.biosciencedbc.jp/kyushu-u/dm3/assembled/ALL.Adl.20.AllAg.Adult_female.bed ...

  1. File list: ALL.Adl.50.AllAg.Adult_male [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available ALL.Adl.50.AllAg.Adult_male dm3 All antigens Adult Adult male SRX013049,SRX013084,S...RX013050,SRX013032,SRX013033,SRX013013 http://dbarchive.biosciencedbc.jp/kyushu-u/dm3/assembled/ALL.Adl.50.AllAg.Adult_male.bed ...

  2. File list: Oth.Adl.05.AllAg.Adult_male_fatbody [Chip-atlas[Archive

    Lifescience Database Archive (English)

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    Lifescience Database Archive (English)

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    Lifescience Database Archive (English)

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  6. File list: ALL.Adl.10.AllAg.Adult_male [Chip-atlas[Archive

    Lifescience Database Archive (English)

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    Lifescience Database Archive (English)

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    Lifescience Database Archive (English)

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  9. File list: ALL.Adl.05.AllAg.Adult_male [Chip-atlas[Archive

    Lifescience Database Archive (English)

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    Lifescience Database Archive (English)

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  11. File list: His.Adl.20.AllAg.Adult_male [Chip-atlas[Archive

    Lifescience Database Archive (English)

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  12. File list: Unc.Adl.50.AllAg.Adult_female [Chip-atlas[Archive

    Lifescience Database Archive (English)

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  13. File list: ALL.Adl.50.AllAg.Adult_male_fatbody [Chip-atlas[Archive

    Lifescience Database Archive (English)

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  14. File list: His.Adl.50.AllAg.Adult_male [Chip-atlas[Archive

    Lifescience Database Archive (English)

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  15. File list: Unc.Adl.20.AllAg.Adult_male_fatbody [Chip-atlas[Archive

    Lifescience Database Archive (English)

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  16. File list: Oth.Adl.10.AllAg.Adult_female [Chip-atlas[Archive

    Lifescience Database Archive (English)

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  17. File list: Unc.Adl.50.AllAg.Adult_male_fatbody [Chip-atlas[Archive

    Lifescience Database Archive (English)

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  18. File list: Pol.Adl.20.AllAg.Adult_male_fatbody [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available Pol.Adl.20.AllAg.Adult_male_fatbody dm3 RNA polymerase Adult Adult male fatbody htt...p://dbarchive.biosciencedbc.jp/kyushu-u/dm3/assembled/Pol.Adl.20.AllAg.Adult_male_fatbody.bed ...

  19. File list: Oth.Adl.20.AllAg.Adult_female [Chip-atlas[Archive

    Lifescience Database Archive (English)

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  20. File list: InP.Adl.05.Input_control.AllCell [Chip-atlas[Archive

    Lifescience Database Archive (English)

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  1. File list: InP.Adl.05.Input_control.AllCell [Chip-atlas[Archive

    Lifescience Database Archive (English)

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  2. File list: InP.Adl.05.AllAg.Octopaminergic_neurons [Chip-atlas[Archive

    Lifescience Database Archive (English)

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  3. File list: ALL.Adl.50.AllAg.Octopaminergic_neurons [Chip-atlas[Archive

    Lifescience Database Archive (English)

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    Lifescience Database Archive (English)

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  5. File list: His.Adl.20.AllAg.Octopaminergic_neurons [Chip-atlas[Archive

    Lifescience Database Archive (English)

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    Lifescience Database Archive (English)

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  7. File list: InP.Adl.20.AllAg.Octopaminergic_neurons [Chip-atlas[Archive

    Lifescience Database Archive (English)

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  9. File list: His.Adl.05.AllAg.Octopaminergic_neurons [Chip-atlas[Archive

    Lifescience Database Archive (English)

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    Lifescience Database Archive (English)

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  11. File list: NoD.Adl.50.AllAg.Octopaminergic_neurons [Chip-atlas[Archive

    Lifescience Database Archive (English)

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  12. File list: His.Adl.10.AllAg.Octopaminergic_neurons [Chip-atlas[Archive

    Lifescience Database Archive (English)

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  13. File list: NoD.Adl.05.AllAg.Octopaminergic_neurons [Chip-atlas[Archive

    Lifescience Database Archive (English)

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    Lifescience Database Archive (English)

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  15. File list: ALL.Adl.10.AllAg.Octopaminergic_neurons [Chip-atlas[Archive

    Lifescience Database Archive (English)

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  16. ADL-3. Nuclear data library for activation and transmutation calculations

    International Nuclear Information System (INIS)

    Grudzevich, O.T.; Zelenetskij, A.V.; Ignatyuk, A.V.; Pashchenko, A.B.

    1995-07-01

    It is shown that the use of simplified approaches to calculate threshold neutron reaction cross-sections is not acceptable for the generation of cross-section libraries. Although rigorous models are complex and involve laborious calculations, they provide the only reliable means for evaluating cross-sections when no experimental data are available. A brief description is given of the new version of the library ADL-3 generated by the authors. It contains 18,200 excitation functions of reactions induced by neutrons of up to 20 MeV. The threshold reaction cross-sections have been calculated in the Hauser-Feshbach-Moldauer formalism with allowance for the contribution of non-equilibrium processes. The cross-sections obtained have been tested by comparison with experimental data and evaluations from other libraries. (author)

  17. Self-reported quality of ADL task performance among patients with COPD exacerbations

    DEFF Research Database (Denmark)

    Bendixen, Hans Jørgen; Wæhrens, Eva Elisabet Ejlersen; Wilcke, Jon Torgny

    2014-01-01

    OBJECTIVE: Patients suffering from chronic obstructive pulmonary disease (COPD) experience problems in the performance of activities of daily living (ADL) tasks. The objective was to examine the self-reported quality of ADL task performance among COPD patients, and to investigate whether age...... concerning age, gender, and routine COPD characteristics were drawn from the patients' medical records. RESULTS: The patients reported being inefficient to markedly inefficient when performing ADL tasks within the personal hygiene, toileting, dressing, household, mobility, and transportation domains. While...... more than 90% of the participants reported increased effort and/or fatigue when performing the ADL tasks, up to 88% of the participants relied on help from others in the performance of general household chores like cooking and shopping. Self-reported ADL ability did not correlate with age, gender...

  18. SLAE–CPS: Smart Lean Automation Engine Enabled by Cyber-Physical Systems Technologies

    Science.gov (United States)

    Ma, Jing; Wang, Qiang; Zhao, Zhibiao

    2017-01-01

    In the context of Industry 4.0, the demand for the mass production of highly customized products will lead to complex products and an increasing demand for production system flexibility. Simply implementing lean production-based human-centered production or high automation to improve system flexibility is insufficient. Currently, lean automation (Jidoka) that utilizes cyber-physical systems (CPS) is considered a cost-efficient and effective approach for improving system flexibility under shrinking global economic conditions. Therefore, a smart lean automation engine enabled by CPS technologies (SLAE–CPS), which is based on an analysis of Jidoka functions and the smart capacity of CPS technologies, is proposed in this study to provide an integrated and standardized approach to design and implement a CPS-based smart Jidoka system. A set of comprehensive architecture and standardized key technologies should be presented to achieve the above-mentioned goal. Therefore, a distributed architecture that joins service-oriented architecture, agent, function block (FB), cloud, and Internet of things is proposed to support the flexible configuration, deployment, and performance of SLAE–CPS. Then, several standardized key techniques are proposed under this architecture. The first one is for converting heterogeneous physical data into uniform services for subsequent abnormality analysis and detection. The second one is a set of Jidoka scene rules, which is abstracted based on the analysis of the operator, machine, material, quality, and other factors in different time dimensions. These Jidoka rules can support executive FBs in performing different Jidoka functions. Finally, supported by the integrated and standardized approach of our proposed engine, a case study is conducted to verify the current research results. The proposed SLAE–CPS can serve as an important reference value for combining the benefits of innovative technology and proper methodology. PMID:28657577

  19. SLAE-CPS: Smart Lean Automation Engine Enabled by Cyber-Physical Systems Technologies.

    Science.gov (United States)

    Ma, Jing; Wang, Qiang; Zhao, Zhibiao

    2017-06-28

    In the context of Industry 4.0, the demand for the mass production of highly customized products will lead to complex products and an increasing demand for production system flexibility. Simply implementing lean production-based human-centered production or high automation to improve system flexibility is insufficient. Currently, lean automation (Jidoka) that utilizes cyber-physical systems (CPS) is considered a cost-efficient and effective approach for improving system flexibility under shrinking global economic conditions. Therefore, a smart lean automation engine enabled by CPS technologies (SLAE-CPS), which is based on an analysis of Jidoka functions and the smart capacity of CPS technologies, is proposed in this study to provide an integrated and standardized approach to design and implement a CPS-based smart Jidoka system. A set of comprehensive architecture and standardized key technologies should be presented to achieve the above-mentioned goal. Therefore, a distributed architecture that joins service-oriented architecture, agent, function block (FB), cloud, and Internet of things is proposed to support the flexible configuration, deployment, and performance of SLAE-CPS. Then, several standardized key techniques are proposed under this architecture. The first one is for converting heterogeneous physical data into uniform services for subsequent abnormality analysis and detection. The second one is a set of Jidoka scene rules, which is abstracted based on the analysis of the operator, machine, material, quality, and other factors in different time dimensions. These Jidoka rules can support executive FBs in performing different Jidoka functions. Finally, supported by the integrated and standardized approach of our proposed engine, a case study is conducted to verify the current research results. The proposed SLAE-CPS can serve as an important reference value for combining the benefits of innovative technology and proper methodology.

  20. Development of technology for fabrication of lithium CPS on basis of CNT-reinforced carboxylic fabric

    International Nuclear Information System (INIS)

    Tazhibayeva, Irina; Baklanov, Viktor; Ponkratov, Yuriy; Abdullin, Khabibulla; Kulsartov, Timur; Gordienko, Yuriy; Zaurbekova, Zhanna; Lyublinski, Igor; Vertkov, Alexey; Skakov, Mazhyn

    2017-01-01

    Highlights: • Preliminary study of carboxylic fabric wettability with liquid lithium is presented. • Preliminary studies of carboxylic fabric wettability with liquid lithium consist in carrying out of experiments at temperatures 673,773 and 873 К in vacuum during long time. • A scheme of experimental device for manufacturing of lithium CPS and matrix filling procedure with liquid lithium are presented. • The concept of lithium limiter with CPS on basis of CNT-reinforced carboxylic fabric is proposed. - Abstract: The paper describes the analysis of liquid lithium interaction with materials based on carbon, the manufacture technology of capillary-porous system (CPS) matrix on basis of CNT-reinforced carboxylic fabric. Preliminary study of carboxylic fabric wettability with liquid lithium is presented. The development of technology includes: microstructural studies of carboxylic fabric before its CNT-reinforcing; validation of CNT-reinforcing technology; mode validation of CVD-method for CNT synthesize; study of synthesized carbon structures. Preliminary studies of carboxylic fabric wettability with liquid lithium consist in carrying out of experiments at temperatures 673, 773 and 873 К in vacuum during long time. The scheme of experimental device for manufacturing of lithium CPS and matrix filling procedure with liquid lithium are presented. The concept of lithium limiter with CPS on basis of CNT-reinforced carboxylic fabric is proposed.

  1. Development of technology for fabrication of lithium CPS on basis of CNT-reinforced carboxylic fabric

    Energy Technology Data Exchange (ETDEWEB)

    Tazhibayeva, Irina, E-mail: tazhibayeva@ntsc.kz [Institute of Atomic Energy, National Nuclear Center of RK, Kurchatov (Kazakhstan); Baklanov, Viktor; Ponkratov, Yuriy [Institute of Atomic Energy, National Nuclear Center of RK, Kurchatov (Kazakhstan); Abdullin, Khabibulla [Institute of Experimental and Theoretical Physics of Kazakh National University, Almaty (Kazakhstan); Kulsartov, Timur; Gordienko, Yuriy; Zaurbekova, Zhanna [Institute of Atomic Energy, National Nuclear Center of RK, Kurchatov (Kazakhstan); Lyublinski, Igor [JSC «Red Star», Moscow (Russian Federation); NRNU «MEPhI», Moscow (Russian Federation); Vertkov, Alexey [JSC «Red Star», Moscow (Russian Federation); Skakov, Mazhyn [Institute of Atomic Energy, National Nuclear Center of RK, Kurchatov (Kazakhstan)

    2017-04-15

    Highlights: • Preliminary study of carboxylic fabric wettability with liquid lithium is presented. • Preliminary studies of carboxylic fabric wettability with liquid lithium consist in carrying out of experiments at temperatures 673,773 and 873 К in vacuum during long time. • A scheme of experimental device for manufacturing of lithium CPS and matrix filling procedure with liquid lithium are presented. • The concept of lithium limiter with CPS on basis of CNT-reinforced carboxylic fabric is proposed. - Abstract: The paper describes the analysis of liquid lithium interaction with materials based on carbon, the manufacture technology of capillary-porous system (CPS) matrix on basis of CNT-reinforced carboxylic fabric. Preliminary study of carboxylic fabric wettability with liquid lithium is presented. The development of technology includes: microstructural studies of carboxylic fabric before its CNT-reinforcing; validation of CNT-reinforcing technology; mode validation of CVD-method for CNT synthesize; study of synthesized carbon structures. Preliminary studies of carboxylic fabric wettability with liquid lithium consist in carrying out of experiments at temperatures 673, 773 and 873 К in vacuum during long time. The scheme of experimental device for manufacturing of lithium CPS and matrix filling procedure with liquid lithium are presented. The concept of lithium limiter with CPS on basis of CNT-reinforced carboxylic fabric is proposed.

  2. Investigation of thermohydraulic parameter variations in operating conditions of Bilibino NPP CPS cooling circuit

    International Nuclear Information System (INIS)

    Baranaev, Yu.D.; Koz'menkova, V.V.; Parafilo, L.M.

    2015-01-01

    In consequence of activities on uncovering the reasons for through faults formation in cooling tubes of reactor control and protection system (CPS) channels of Bilibino-2 reactor the conclusion is made that corrosion failure development takes place against the backdrop of periodic increase of total moisture in reactor space at transient and standby modes at top of cooling tubes of CPS channels. Formation of corrosion defects in cooling tubes of four CPS channels of unit 2 in 2011-2012 is specific factor for this plant unit and do not effect on operation of other plant units. It is pointed out that ingress of moisture into gas system of the reactor is the critical factor providing integrity of structure elements of EhPG-6 reactor core cooling system. This fact agrees nicely with the results obtained during operation AM reactor of the First NPP [ru

  3. An Anonymous Access Authentication Scheme Based on Proxy Ring Signature for CPS-WMNs

    Directory of Open Access Journals (Sweden)

    Tianhan Gao

    2017-01-01

    Full Text Available Access security and privacy have become a bottleneck for the popularization of future Cyber-Physical System (CPS networks. Furthermore, users’ need for privacy-preserved access during movement procedure is more urgent. To address the anonymous access authentication issue for CPS Wireless Mesh Network (CPS-WMN, a novel anonymous access authentication scheme based on proxy ring signature is proposed. A hierarchical authentication architecture is presented first. The scheme is then achieved from the aspect of intergroup and intragroup anonymous mutual authentication through proxy ring signature mechanism and certificateless signature mechanism, respectively. We present a formal security proof of the proposed protocol with SVO logic. The simulation and performance analysis demonstrate that the proposed scheme owns higher efficiency and adaptability than the typical one.

  4. Self-reported Quality of ADL Task Performance in Adults with Schizophrenia

    DEFF Research Database (Denmark)

    Nielsen, Kristina Tomra; Petersen, Rikke S.; Wæhrens, Eva Ejlersen

    quality of both personal ADL (PADL) and instrumental ADL (IADL). Aside from decreased independence, the participants also reported problems related to increased effort, increased use of time, and some safety issues. Although most of the participants reported to be competent in relation to PADL tasks......, how they perceive the quality of their performance in terms of effort/fatigue, use of time, safety risks, and need for assistance. The aim was to investigate the self-reported quality of ADL task performance in adults with schizophrenia. Subjects Participants were recruited from October 2013...... evaluation tool developed to describe and measure the quality of ADL task performance in terms of effort/fatigue, use of time, safety risks, and need for assistance based on self-report. Occupational therapists employed at the hospitals and trained in conducting the ADL–I were collecting data. The interviews...

  5. A Process for the Representation of openEHR ADL Archetypes in OWL Ontologies.

    Science.gov (United States)

    Porn, Alex Mateus; Peres, Leticia Mara; Didonet Del Fabro, Marcos

    2015-01-01

    ADL is a formal language to express archetypes, independent of standards or domain. However, its specification is not precise enough in relation to the specialization and semantic of archetypes, presenting difficulties in implementation and a few available tools. Archetypes may be implemented using other languages such as XML or OWL, increasing integration with Semantic Web tools. Exchanging and transforming data can be better implemented with semantics oriented models, for example using OWL which is a language to define and instantiate Web ontologies defined by W3C. OWL permits defining significant, detailed, precise and consistent distinctions among classes, properties and relations by the user, ensuring the consistency of knowledge than using ADL techniques. This paper presents a process of an openEHR ADL archetypes representation in OWL ontologies. This process consists of ADL archetypes conversion in OWL ontologies and validation of OWL resultant ontologies using the mutation test.

  6. Streptococcus iniae cpsG alters capsular carbohydrate composition and is a cause of serotype switching in vaccinated fish.

    Science.gov (United States)

    Heath, Candice; Gillen, Christine M; Chrysanthopoulos, Panagiotis; Walker, Mark J; Barnes, Andrew C

    2016-09-25

    Streptococcus iniae causes septicaemia and meningitis in marine and freshwater fish wherever they are farmed in warm-temperate and tropical regions. Although serotype specific, vaccination with bacterins (killed bacterial cultures) is largely successful and vaccine failure occurs only occasionally through emergence of new capsular serotypes. Previously we showed that mutations in vaccine escapes are restricted to a limited repertoire of genes within the 20-gene capsular polysaccharide (cps) operon. cpsG, a putative UDP-galactose 4-epimerase, has three sequence types based on the insertion or deletion of the three amino acids leucine, serine and lysine in the substrate binding site of the protein. To elucidate the role of cpsG in capsular polysaccharide (CPS) biosynthesis and capsular composition, we first prepared isogenic knockout and complemented mutants of cpsG by allelic exchange mutagenesis. Deletion of cpsG resulted in changes to colony morphology and cell buoyant density, and also significantly decreased galactose content relative to glucose in the capsular polysaccharide as determined by GC-MS, consistent with epimerase activity of CpsG. There was also a metabolic penalty of cpsG knockout revealed by slower growth in complex media, and reduced proliferation in whole fish blood. Moreover, whilst antibodies raised in fish against the wild type cross-reacted in whole cell and cps ELISA, they did not cross-opsonise the mutant in a peripheral blood neutrophil opsonisation assay, consistent with reported vaccine escape. We have shown here that mutation in cpsG results in altered CPS composition and this in turn results in poor cross-opsonisation that explains some of the historic vaccination failure on fish farms in Australia. Crown Copyright © 2016. Published by Elsevier B.V. All rights reserved.

  7. Reliable CPS design for mitigating semiconductor and battery aging in electric vehicles

    NARCIS (Netherlands)

    Chang, W.; Proebstl, A.; Goswami, D.; Zamani, M.; Chakraborty, S.

    2015-01-01

    Reliability and performance of cyber-physical systems (CPS) in electric vehicles (EVs) are influenced by three design aspects: (i) controller design, (ii) battery usage, i.e., Battery rate capacity and aging effects, (iii) processor aging of the in-vehicle embedded platform. In this paper, we

  8. Diffusive Promotion by Velocity Gradient of Cytoplasmic Streaming (CPS in Nitella Internodal Cells.

    Directory of Open Access Journals (Sweden)

    Kenji Kikuchi

    Full Text Available Cytoplasmic streaming (CPS is well known to assist the movement of nutrients, organelles and genetic material by transporting all of the cytoplasmic contents of a cell. CPS is generated by motility organelles that are driven by motor proteins near a membrane surface, where the CPS has been found to have a flat velocity profile in the flow field according to the sliding theory. There is a consistent mixing of contents inside the cell by CPS if the velocity gradient profile is flattened, which is not assisted by advection diffusion but is only supported by Brownian diffusion. Although the precise flow structure of the cytoplasm has an important role for cellular metabolism, the hydrodynamic mechanism of its convection has not been clarified. We conducted an experiment to visualise the flow of cytoplasm in Nitella cells by injecting tracer fluorescent nanoparticles and using a flow visualisation system in order to understand how the flow profile affects their metabolic system. We determined that the velocity field in the cytosol has an obvious velocity gradient, not a flattened gradient, which suggests that the gradient assists cytosolic mixing by Taylor-Aris dispersion more than by Brownian diffusion.

  9. 77 FR 58510 - Proposed Information Collection; Comment Request; Current Population Survey (CPS), Annual Social...

    Science.gov (United States)

    2012-09-21

    ... various population groups. A prime statistic of interest is the classification of people in poverty and... Information Collection; Comment Request; Current Population Survey (CPS), Annual Social and Economic... conducted this supplement annually for over 50 years. The Census Bureau and the Bureau of Labor Statistics...

  10. Development of the Childbirth Perception Scale (CPS) : Perception of delivery and the first postpartum week

    NARCIS (Netherlands)

    Truijens, Sophie E. M.; Wijnen, Hennie A.; Pommer, Antoinette M.; Oei, S. Guid; Pop, Victor J. M.

    2014-01-01

    Some caregivers suggest a more positive experience of childbirth when giving birth at home. Since properly developed instruments that assess women’s perception of delivery and the early postpartum are missing, the aim of the current study is to develop a Childbirth Perception Scale (CPS). Three

  11. Medium-Chain Chlorinated Paraffins (CPs) Dominate in Australian Sewage Sludge

    NARCIS (Netherlands)

    Brandsma, Sicco H; van Mourik, Louise; O'Brien, Jake W; Eaglesham, Geoff; Leonards, Pim E G; de Boer, Jacob; Gallen, Christie; Mueller, Jochen; Gaus, Caroline; Bogdal, Christian

    2017-01-01

    To simultaneously quantify and profile the complex mixture of short-, median-, and long-chain CPs (SCCPs, MCCPs, and LCCPs) in Australian sewage sludge, we applied and further validated a recently developed novel instrumental technique, using quadrupole time-of-flight high resolution mass

  12. Determination of tritium generation and release parameters at lithium CPS under neutron irradiation

    Energy Technology Data Exchange (ETDEWEB)

    Ponkratov, Yuriy, E-mail: ponkratov@nnc.kz [Institute of Atomic Energy, National Nuclear Center of RK, Kurchatov (Kazakhstan); Baklanov, Viktor; Skakov, Mazhyn; Kulsartov, Timur; Tazhibayeva, Irina; Gordienko, Yuriy; Zaurbekova, Zhanna; Tulubayev, Yevgeniy [Institute of Atomic Energy, National Nuclear Center of RK, Kurchatov (Kazakhstan); Chikhray, Yevgeniy [Institute of Experimental and Theoretical Physics of Kazakh National University, Almaty (Kazakhstan); Lyublinski, Igor [JSC “Star”, Moscow (Russian Federation); NRNU “MEPhI”, Moscow (Russian Federation); Vertkov, Alexey [JSC “Star”, Moscow (Russian Federation)

    2016-11-01

    Highlights: • The main parameters of tritium generation and release from lithium capillary-porous system (CPS) under neutron irradiation at the IVG.1 M research reactor is described in paper. • In the experiments a very small tritium release was fixed likely due to its high solubility in liquid lithium. • If the lithium CPS will be used as a plasma facing material in temperature range up to 773 K under neutron irradiation only helium will release from lithium CPS into a vacuum chamber. - Abstract: This paper describes the main parameters of tritium generation and release from lithium capillary-porous system (CPS) under neutron irradiation at the IVG.1 M research reactor. The experiments were carried out using the method of mass-spectrometric registration of released gases and using a specially constructed ampoule device. Irradiation was carried out at different reactor thermal powers (1, 2 and 6 MW) and sample temperatures from 473 to 773 K. In the experiments a very small tritium release was detected likely due to its high solubility in liquid lithium. It can be caused by formation of lithium tritide during tritium diffusion to the lithium surface.

  13. 76 FR 75869 - Proposed Information Collection; Comment Request; Current Population Survey (CPS) Fertility...

    Science.gov (United States)

    2011-12-05

    ... of the first birth. Potential needs for government assistance, such as aid to families with dependent children, child care, and maternal health care for single parent households, can be estimated using CPS... child spacing, and to aid policymakers in their decisions affected by changes in family size and...

  14. MPM4CPS: multi-pardigm modelling for cyber-physical systems

    NARCIS (Netherlands)

    Vangeheluwe, Hans; Ameral, Vasco; Giese, Holger; Broenink, Johannes F.; Schätz, Bernhard; Norta, Alexander; Carreira, Paulo; Lukovic, Ivan; Mayerhofer, Tanja; Wimmer, Manuel; Vellecillo, Antonio

    2016-01-01

    The last decades have seen the emergence of truly complex, designed systems, known as Cyber-Physical Systems (CPS). Engineering such systems requires integrating physical, software, and network aspects. To date, neither a unifying theory nor systematic design methods, techniques and tools exist to

  15. 78 FR 45910 - Proposed Information Collection; Comment Request; Current Population Survey (CPS) Email Address...

    Science.gov (United States)

    2013-07-30

    ... Population Survey (CPS) Email Address Collection Test Supplement AGENCY: U.S. Census Bureau, Commerce. ACTION... request clearance for the collection of data concerning the November 2013 Email Address Collection Test... tool to help increase response rates. We foresee that in the future, we could collect email addresses...

  16. Automated glycan assembly of a S. pneumoniae serotype 3 CPS antigen

    Directory of Open Access Journals (Sweden)

    Markus W. Weishaupt

    2016-07-01

    Full Text Available Vaccines against S. pneumoniae, one of the most prevalent bacterial infections causing severe disease, rely on isolated capsular polysaccharide (CPS that are conjugated to proteins. Such isolates contain a heterogeneous oligosaccharide mixture of different chain lengths and frame shifts. Access to defined synthetic S. pneumoniae CPS structures is desirable. Known syntheses of S. pneumoniae serotype 3 CPS rely on a time-consuming and low-yielding late-stage oxidation step, or use disaccharide building blocks which limits variability. Herein, we report the first iterative automated glycan assembly (AGA of a conjugation-ready S. pneumoniae serotype 3 CPS trisaccharide. This oligosaccharide was assembled using a novel glucuronic acid building block to circumvent the need for a late-stage oxidation. The introduction of a washing step with the activator prior to each glycosylation cycle greatly increased the yields by neutralizing any residual base from deprotection steps in the synthetic cycle. This process improvement is applicable to AGA of many other oligosaccharides.

  17. Implementation of the On-the-fly Encryption for the Linux OS Based on Certified CPS

    Directory of Open Access Journals (Sweden)

    Alexander Mikhailovich Korotin

    2013-02-01

    Full Text Available The article is devoted to tools for on-the-fly encryption and a method to implement such tool for the Linux OS based on a certified CPS.The idea is to modify the existing tool named eCryptfs. Russian cryptographic algorithms will be used in the user and kernel modes.

  18. Blockchain-Oriented Coalition Formation by CPS Resources: Ontological Approach and Case Study

    Directory of Open Access Journals (Sweden)

    Alexey Kashevnik

    2018-05-01

    Full Text Available Cyber-physical systems (CPS, robotics, Internet of Things, information and communication technologies have become more and more popular over the last several years. These topics open new perspectives and scenarios that can automate processes in human life. CPS are aimed at interaction support in information space for physical entities communicated in physical space in real time. At the same time the blockchain technology that becomes popular last years allows to organize immutable distributed database that store all significant information and provide access for CPS participants. The paper proposes an approach that is based on ontology-based context management, publish/subscribe semantic interoperability support, and blockchain techniques. Utilization of these techniques provide possibilities to develop CPS that supports dynamic, distributed, and stable coalition formation of the resources. The case study presented has been implemented for the scenario of heterogeneous mobile robots’ collaboration for the overcoming of obstacles. There are two types of robots and an information service participating in the scenario. Evaluation shows that the proposed approach is applicable for the presented class of scenarios.

  19. STRATEGI PEMBELAJARAN CREATIVE PROBLEM SOLVING (CPS BERBASIS EKSPERIMEN UNTUK MENINGKATKAN KEMAMPUAN KOGNITIF DAN KETERAMPILAN BERPIKIR KREATIF

    Directory of Open Access Journals (Sweden)

    Ahmad Busyairi

    2015-09-01

    Full Text Available This study aimed to get an idea related to the development of cognitive abilities and creative thinking skills in problem solving student after being given treatment with CPS-based experimental learning and conventional learning. The method used in this research is a quasi-experimental design with the randomized pretest-posttest control group design. The research sample group of 58 high school students who are divided into two classes (class 29 experimental and 29 control group. The collected data was then analyzed using N-gain calculation, t-test, and the calculation of effect size. The result showed that the students' cognitive abilities for both classes equally increased by the moderate category. For the creative thinking skills of students in problem solving, experimental class increased by categories was increased while the control class with low category. Based on the test results show that the application of learning hypothesis-based experiments CPS can significantly improve the cognitive abilities and skills of creative thinking in solving problems of students compared to the application of conventional learning. In addition, based on the calculation of effect size indicates that the application of experiment-based learning CPS effective in improving cognitive ability and creative thinking skills in problem solving students with moderate category. ABSTRAK Penelitian ini bertujuan untuk mendapatkan gambaran terkait peningkatan kemampuan kognitif dan keterampilan berpikir kreatif dalam pemecahan masalah siswa setelah diberikan perlakuan dengan pembelajaran CPS berbasis eksperimen dan pembelajaran kovensional. Metode yang digunakan dalam penelitian ini adalah metode kuasi eksperimen dengan desain the randomized pretest-posttest control group design. Sampel penelitian sebanyak 58 siswa SMA yang dibagi ke dalam dua kelas (29 kelas eksperimen dan 29 kelas kontrol. Data yang terkumpul kemudian dianalisis dengan menggunakan perhitungan N

  20. The course of apraxia and ADL functioning in left hemisphere stroke patients treated in rehabilitation centres and nursing homes.

    OpenAIRE

    Donkervoort, M.; Dekker, J.; Deelman, B.

    2006-01-01

    OBJECTIVE: To study the course of apraxia and daily life functioning (ADL) in left hemisphere stroke patients with apraxia. DESIGN: Prospective cohort study. SETTING: Rehabilitation centres and nursing homes. SUBJECTS: One hundred and eight left hemisphere stroke patients with apraxia, hospitalized in rehabilitation centres and nursing homes. MEASURES: ADL-observations, Barthel ADL Index, Apraxia Test, Motricity Index. RESULTS: During the study period of 20 weeks, patients showed small improv...

  1. Total synthesis of a Streptococcus pneumoniae serotype 12F CPS repeating unit hexasaccharide

    Directory of Open Access Journals (Sweden)

    Peter H. Seeberger

    2017-01-01

    Full Text Available The Gram-positive bacterium Streptococcus pneumoniae causes severe disease globally. Vaccines that prevent S. pneumoniae infections induce antibodies against epitopes within the bacterial capsular polysaccharide (CPS. A better immunological understanding of the epitopes that protect from bacterial infection requires defined oligosaccharides obtained by total synthesis. The key to the synthesis of the S. pneumoniae serotype 12F CPS hexasaccharide repeating unit that is not contained in currently used glycoconjugate vaccines is the assembly of the trisaccharide β-D-GalpNAc-(1→4-[α-D-Glcp-(1→3]-β-D-ManpNAcA, in which the branching points are equipped with orthogonal protecting groups. A linear approach relying on the sequential assembly of monosaccharide building blocks proved superior to a convergent [3 + 3] strategy that was not successful due to steric constraints. The synthetic hexasaccharide is the starting point for further immunological investigations.

  2. A game-theoretic method for cross-layer stochastic resilient control design in CPS

    Science.gov (United States)

    Shen, Jiajun; Feng, Dongqin

    2018-03-01

    In this paper, the cross-layer security problem of cyber-physical system (CPS) is investigated from the game-theoretic perspective. Physical dynamics of plant is captured by stochastic differential game with cyber-physical influence being considered. The sufficient and necessary condition for the existence of state-feedback equilibrium strategies is given. The attack-defence cyber interactions are formulated by a Stackelberg game intertwined with stochastic differential game in physical layer. The condition such that the Stackelberg equilibrium being unique and the corresponding analytical solutions are both provided. An algorithm is proposed for obtaining hierarchical security strategy by solving coupled games, which ensures the operational normalcy and cyber security of CPS subject to uncertain disturbance and unexpected cyberattacks. Simulation results are given to show the effectiveness and performance of the proposed algorithm.

  3. Using creative problem solving (CPS) to improve leadership in a non-profit organization

    OpenAIRE

    Sousa, Fernando; Castelão, Paula; Monteiro, Ileana Pardal; Pellissier, René

    2013-01-01

    The purpose of this study was to evaluate the effectiveness of the Creative Problem Solving (CPS) method in improving the leadership process in a non-profit organization. The research was designed around an intervention and structured in three stages (pre-consult, intervention and follow-up), with a team designated by management, in order to bring leadership cohesion to both departments of the organization and also between the board and executive management. The results, expressed in the task...

  4. Analysis mathematical literacy skills in terms of the students’ metacognition on PISA-CPS model

    Science.gov (United States)

    Ovan; Waluya, S. B.; Nugroho, S. E.

    2018-03-01

    This research was aimed to know the effectiveness of PISA-CPS model and desceibe the mathematical literacy skills (KLM) in terms of the students’ metacognition. This study used Mixed Methods approaches with the concurrent embedded desaign. The technique of data analysis on quantitative research done analysis of lesson plan, prerequisite test, test hypotesis 1 and hypotesis test. While qualitative research done data reduction, data presentation, and drawing conclution and data verification. The subject of this study was the students of Grade Eight (VIII) of SMP Islam Sultan Agung 4 Semarang, Central Java. The writer analyzed the data with quantitative and qualitative approaches based on the metacognition of the students in low, medium and high groups. Subsequently, taken the mathematical literacy skills (KLM) from students’ metacognition in low, medium, and high . The results of the study showed that the PISA-CPS model was complete and the students’ mathematical literacy skills in terms of the students’ metacognition taught by the PISA-CPS model was higher than the expository learning. metacognitions’ students classified low hadmathematical literacy skills (KLM) less good, metacognitions’ students classified medium had mathematical literacy skills (KLM) good enough, metacognitions’ students classified high had mathematical literacy skills (KLM) very good. Based onresult analysis got conclusion that the PISA-CPS model was effective toward the students’ mathematical literacy skills (KLM). To increase the students’ mathematical literacy skills (KLM), the teachers need to provide reinforcements in the form of the exercises so that the student’s mathematical literacy was achieved at level 5 and level 6.

  5. Effect of eccentric location of the RBMK CPS displacer graphite block in the shielding sheath

    International Nuclear Information System (INIS)

    Dostov, A.I.

    2001-01-01

    Temperature conditions and accumulation of Wigner energy in the graphite block of the RBMK reactor CPS (control power system) displacer is examined. It is shown, that at eccentric location of the block in the shielding sheath average temperature of the block drops sharply. Due to the design demerit quantity of the stored energy in the block may be so great, that its release will result in melting of the displacer tube. (author)

  6. Medium-Chain Chlorinated Paraffins (CPs) Dominate in Australian Sewage Sludge.

    Science.gov (United States)

    Brandsma, Sicco H; van Mourik, Louise; O'Brien, Jake W; Eaglesham, Geoff; Leonards, Pim E G; de Boer, Jacob; Gallen, Christie; Mueller, Jochen; Gaus, Caroline; Bogdal, Christian

    2017-03-21

    To simultaneously quantify and profile the complex mixture of short-, median-, and long-chain CPs (SCCPs, MCCPs, and LCCPs) in Australian sewage sludge, we applied and further validated a recently developed novel instrumental technique, using quadrupole time-of-flight high resolution mass spectrometry running in the negative atmospheric pressure chemical ionization mode (APCI-qTOF-HRMS). Without using an analytical column the cleaned extracts were directly injected into the qTOF-HRMS followed by quantification of the CPs by a mathematical algorithm. The recoveries of the four SCCP, MCCP and LCCP-spiked sewage sludge samples ranged from 86 to 123%. This APCI-qTOF-HRMS method is a fast and promising technique for routinely measuring SCCPs, MCCPs, and LCCPs in sewage sludge. Australian sewage sludge was dominated by MCCPs with concentrations ranging from 542 to 3645 ng/g dry weight (dw). Lower SCCPs concentrations (<57-1421 ng/g dw) were detected in the Australian sewage sludge, which were comparable with the LCCPs concentrations (116-960 ng/g dw). This is the first time that CPs were reported in Australian sewage sludge. The results of this study gives a first impression on the distribution of the SCCPs, MCCPs, and LCCPs in Australia wastewater treatment plants (WWTPs).

  7. On the spatial behavior of background plasma in different background pressure in CPS device

    International Nuclear Information System (INIS)

    Samantaray, Subrata; Paikaray, Rita; Sahoo, Gourishankar; Das, Parthasarathi; Ghosh, Joydeep; Sanyasi, Amulya Kumar

    2015-01-01

    Blob formation and transport is a major concern for investigators as it greatly reduces the efficiency of the devices. Initial results from CPS device confirm the role of fast neutrals inside the bulk plasma in the process of blob formation and transport. 2-D simulation of curvature and velocity shear instability in plasma structures suggest that in the presence of background plasma, secondary instability do not grow non-linearly to a high level and stabilizes the flow. Adiabaticity effect also creates a radial barrier for interchange modes. In the absence of background plasma the blob fragments even at the modest level of viscosity. The fast neutrals outside bulk plasma supposed to stabilize the system. The background plasma set up is aimed at creating fast neutrals outside main plasma column, hence; the background plasma set up is done in CPS device. The spatial behavior of plasma column in between electrodes is different for different base pressure in CPS device. The spatial variation of electron temperature of plasma column between electrodes is presented in this communication. Electron temperature is measured from emission spectroscopy data. The maximum electron temperature (line averaged) is ∼ 1.5 eV. (author)

  8. Verificación del cumplimiento de los criterios CPS de la NERC en el SNI del Ecuador; Verification of the execution of the CPS approachies of NEPC in the national interconnected System of Ecuador

    Directory of Open Access Journals (Sweden)

    Marcelo Arias Castañeda

    2011-02-01

    Full Text Available En este artículo se describe el procedimiento utilizado para la evaluación del controlautomático de la generación en el Sistema Nacional Interconectado (SNI del Ecuador,tomando como marco de referencia los criterios CPS-1 y CPS-2 (Control PerformanceStandars por sus siglas en inglés. de la NERC. El artículo está dividido en secciones queexplican en detalle en qué consisten los criterios CPS de la NERC, cómo se calculan loslímites de estos criterios teniendo en consideración las condiciones específicas del sistemaeléctrico ecuatoriano (sección 2, y cómo se aplican los criterios en la evaluación del controlautomático de la generación en el SNI del Ecuador teniendo en cuenta la interconexión conColombia (sección 3. Además se sugiere el valor mínimo de BIAS a fijar en el sistemaecuatoriano para el cumplimiento del criterio CPS-2. This paper presents an analytic framework for the formulation and evaluation of automaticgeneration control in the Ecuadorian Electrical System (SNI taking like reference mark theapproaches CPS-1 and CPS-2 of NERC. The article is divided in sections that they explain indetail the approaches CPS of NERC, how the limits of these approaches are calculated havingin consideration the specific conditions of the electric Ecuadorian system (section 2, and howthe approaches are applied in the evaluation of the automatic control of the generation in SNIof Ecuador keeping in mind the interconnection with Colombia (section 3. The minimum valueof BIAS is also suggested to fix in the Ecuadorian system for the execution of the approachCPS-2.

  9. Panel summary of cyber-physical systems (CPS) and Internet of Things (IoT) opportunities with information fusion

    Science.gov (United States)

    Blasch, Erik; Kadar, Ivan; Grewe, Lynne L.; Brooks, Richard; Yu, Wei; Kwasinski, Andres; Thomopoulos, Stelios; Salerno, John; Qi, Hairong

    2017-05-01

    During the 2016 SPIE DSS conference, nine panelists were invited to highlight the trends and opportunities in cyber-physical systems (CPS) and Internet of Things (IoT) with information fusion. The world will be ubiquitously outfitted with many sensors to support our daily living thorough the Internet of Things (IoT), manage infrastructure developments with cyber-physical systems (CPS), as well as provide communication through networked information fusion technology over the internet (NIFTI). This paper summarizes the panel discussions on opportunities of information fusion to the growing trends in CPS and IoT. The summary includes the concepts and areas where information supports these CPS/IoT which includes situation awareness, transportation, and smart grids.

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  5. Performance-based assessment of activities of daily living (ADL) ability among women with chronic widespread pain

    DEFF Research Database (Denmark)

    Wæhrens, Eva Ejlersen; Amris, Kirstine; Fisher, Anne G

    2010-01-01

    . The investigated psychometric properties of the AMPS included discrimination between a sample of healthy women and those with chronic widespread pain, as well as stability when no intervention was provided and sensitivity to change following intervention. Data were obtained based on a repeated measures design......-report and performance-based assessment of ADL offer distinct but complementary information about ability. The present study, therefore, investigated the applicability of a performance-based measure of ADL ability, the Assessment of Motor and Process Skills (AMPS), among 50 women with chronic widespread pain...... performing AMPS evaluations twice pre- and twice post-rehabilitation. Results indicated that the ADL motor ability measures of the participants were significantly lower than those of healthy women of same age, the ADL motor and ADL process ability measures remained stable when no intervention was provided...

  6. Hospital Readmission among Older Adults Who Return Home with Unmet Need for ADL Disability

    Science.gov (United States)

    DePalma, Glen; Xu, Huiping; Covinsky, Kenneth E.; Craig, Bruce A.; Stallard, Eric; Thomas, Joseph, III.; Sands, Laura P.

    2013-01-01

    Purpose: This study determined whether returning to the community from a recent hospitalization with unmet activities of daily living (ADL) need was associated with probability of readmission. Methods: A total of 584 respondents to the 1994, 1999, and/or 2004 National Long-Term Care Surveys (NLTCS) who were hospitalized within 90 days prior to the…

  7. QMG and MG-ADL correlations: Study of eculizumab treatment of myasthenia gravis.

    Science.gov (United States)

    Howard, James F; Freimer, Miriam; O'Brien, Fanny; Wang, Jing Jing; Collins, Stephen R; Kissel, John T

    2017-08-01

    A phase 2 study of eculizumab for treating myasthenia gravis (MG) used the quantitative myasthenia gravis score (QMG) and myasthenia gravis activities of daily living profile (MG-ADL) to evaluate baseline disease severity and treatment response. Correlations were then analyzed between these assessments. Patients were given eculizumab or placebo during the first 16-week treatment period of the crossover study, with treatment assignments reversed for the second treatment period following a 5-week washout. QMG and MG-ADL scores at baseline and endpoint of each treatment period generated correlation coefficients for baseline status and treatment response during eculizumab therapy. Correlation strength between QMG and MG-ADL scores was higher for treatment response (R = 0.726; 95% confidence interval, 0.264-0.907; P = 0.0036) than for assessing baseline disease status (R = 0.552; 95% confidence interval, -0.022-0.839; P = 0.0495). MG-ADL may be more sensitive for assessing treatment response than point-in-time disease status. Muscle Nerve 56: 328-330, 2017. © 2016 Wiley Periodicals, Inc.

  8. Clinical characteristics with an impact on ADL functions of PD patients with cognitive impairment indicative of dementia.

    Directory of Open Access Journals (Sweden)

    Inga Liepelt-Scarfone

    Full Text Available BACKGROUND: Dementia in Parkinson's disease (PD is defined as cognitive decline severe enough to affect activities of daily living function (ADL. The aim of our exploratory study was to compare two groups of PD patients. Both groups had cognitive deficits severe enough to justify diagnosis of dementia, but they differed according to caregivers' rating on ADL dysfunction. Parameters which differed between the two groups were interpreted to affect the caregivers' perception of ADL dysfunction in PD patients with cognitive impairment indicative of Parkinson's disease dementia. METHODOLOGY/PRINCIPAL FINDINGS: Thirty of 131 Parkinson's disease patients fulfilled the Movement Disorders Society Task Force - recommended, cognitive Level-I-criteria for dementia. According to standardized caregiver ratings, volunteers were grouped into 18 patients with (ADL- and 12 without instrumental activities of daily living dysfunction (ADL+. Caregiver activities of daily living function ratings closely correlated with self-estimates of patients and those of physician (p<0.001. ADL- patients performed worse on tests assessing visual-construction (p<0.05 and attention (p=0.03 than ADL+ patients. Moreover, the postural instability and gait disorder subtype was more frequent in ADL- patients (p=0.009. ADL- patients tended to have more communication problems (p=0.05, more anxiety (p=0.05 and showed a tendency to be treated more often with neuroleptics (p=0.049 than ADL+. CONCLUSIONS/SIGNIFICANCE: Results indicate that worse attention, visual-construction abilities, the postural instability and gait disorder subtype, communication problems, medication and presence of anxiety are related to activities of daily living dysfunctions in Parkinson's disease patients with cognitive decline indicative of dementia. Our data suggests that not only cognitive factors but also non-cognitive factors seem to be linked to the diagnosis of Parkinson's disease dementia associated with

  9. The course of apraxia and ADL functioning in left hemisphere stroke patients treated in rehabilitation centres and nursing homes.

    Science.gov (United States)

    Donkervoort, Mireille; Dekker, Joost; Deelman, Betto

    2006-12-01

    To study the course of apraxia and daily life functioning (ADL) in left hemisphere stroke patients with apraxia. Prospective cohort study. Rehabilitation centres and nursing homes. One hundred and eight left hemisphere stroke patients with apraxia, hospitalized in rehabilitation centres and nursing homes. ADL-observations, Barthel ADL Index, Apraxia Test, Motricity Index. During the study period of 20 weeks, patients showed small improvements in apraxia (standardized mean differences of 0.19 and 0.33) and medium-sized improvements in ADL functioning (standardized mean differences from 0.37 to 0.61). About 88% of the patients were still apraxic at week 20. Less improvement in apraxia was observed in initially less severe apraxic patients. Less improvement in ADL functioning was found to be associated with more severe apraxia, a more independent initial ADL score, higher age, impaired motor functioning and longer time between stroke and first assessment. Apraxia in stroke patients is a persistent disorder, which has an adverse influence on ADL recovery.

  10. Modeling of continuous withdrawal and falling out of CPS control rods accident, using QUABOX/CUBBOX-HYCA code

    International Nuclear Information System (INIS)

    Bubelis, E.; Pabarcius, R.; Tonkunas, A.

    2003-01-01

    At present, at the Ignalina NPP the process of a wider use of the new uranium-erbium fuel of higher saturation and the manual control rods of new design is going on. These actions are directed to reducing the reactor control and protection system (CPS) cooling circuit voiding effect and to improving the technical and economical reactor operation parameters. Continuous withdrawal and falling out of CPS control rods lead to the reactivity and power changes in the reactor core. Therefore, important for safety is the evaluation of the CPS ability to compensate for the resulting excess reactivity in the reactor core, having the changed core loading conditions during such accidents. This article presents the calculation results of the continuous withdrawal and falling out of CPS control rods for the specific reactor core conditions of the Ignalina NPP Unit 2, i.e. during its operation on the maximum allowed power level of 4200 MW. The German code QUABOX/CUBBOX-HYCA with the improved CPS logic was used for the simulation of the above-mentioned transients. (author)

  11. Interaction of valleys and circulation patterns (CPs on spatial precipitation patterns in southern Germany

    Directory of Open Access Journals (Sweden)

    M. Liu

    2013-11-01

    Full Text Available Topography exerts influence on the spatial precipitation distribution over different scales, known typically at the large scale as the orographic effect, and at the small scale as the wind-drift rainfall (WDR effect. At the intermediate scale (1~10 km, which is characterized by secondary mountain valleys, topography also demonstrates some effect on the precipitation pattern. This paper investigates such intermediate-scale topographic effects on precipitation patterns, focusing on narrow-steep valleys in the complex terrain of southern Germany, based on the daily observations over a 48 yr period (1960~2007 from a high-density rain-gauge network covering two sub-areas, Baden-Wuerttemberg (BW and Bavaria (BY. Precipitation data at the valley and non-valley stations are compared under consideration of the daily general circulation patterns (CPs classified by a fuzzy rule-based algorithm. Scatter plots of precipitation against elevation demonstrate a different behavior of valley stations comparing to non-valley stations. A detailed study of the precipitation time series for selected station triplets, each consisting of a valley station, a mountain station and an open station have been investigated by statistical analysis with the Kolmogorov–Smirnov (KS test supplemented by the One-way analysis of variance (One-way ANOVA and a graphical comparison of the mean precipitation amounts. The results show an interaction of valley orientation and the direction of the CPs at the intermediate scale, i.e. when the valley is shielded from the CP which carries the precipitation, the precipitation amount within the valley is comparable to that on the mountain crest, and both larger than the precipitation at the open station. When the valley is open to the CP, the precipitation within the valley is similar to the open station but much less than that on the mountain. Such phenomenon where the precipitation is "blind" to the valleys at the intermediate scale

  12. Effects of aquatic PNF lower extremity patterns on balance and ADL of stroke patients

    OpenAIRE

    Kim, Eun-Kyung; Lee, Dong-Kyu; Kim, Young-Mi

    2015-01-01

    [Purpose] This study investigated the effect of aquatic proprioceptive neuromuscular facilitation (PNF) patterns in the lower extremity on balance and activities of daily living (ADL) in stroke patients. [Subjects] Twenty poststroke participants were randomly assigned to an experimental group (n = 10) or a control group (n = 10). The experimental group performed lower extremity patterns in an aquatic environment, and the control group performed lower extremity patterns on the ground. Both exe...

  13. Algorithm integration using ADL (Algorithm Development Library) for improving CrIMSS EDR science product quality

    Science.gov (United States)

    Das, B.; Wilson, M.; Divakarla, M. G.; Chen, W.; Barnet, C.; Wolf, W.

    2013-05-01

    Algorithm Development Library (ADL) is a framework that mimics the operational system IDPS (Interface Data Processing Segment) that is currently being used to process data from instruments aboard Suomi National Polar-orbiting Partnership (S-NPP) satellite. The satellite was launched successfully in October 2011. The Cross-track Infrared and Microwave Sounder Suite (CrIMSS) consists of the Advanced Technology Microwave Sounder (ATMS) and Cross-track Infrared Sounder (CrIS) instruments that are on-board of S-NPP. These instruments will also be on-board of JPSS (Joint Polar Satellite System) that will be launched in early 2017. The primary products of the CrIMSS Environmental Data Record (EDR) include global atmospheric vertical temperature, moisture, and pressure profiles (AVTP, AVMP and AVPP) and Ozone IP (Intermediate Product from CrIS radiances). Several algorithm updates have recently been proposed by CrIMSS scientists that include fixes to the handling of forward modeling errors, a more conservative identification of clear scenes, indexing corrections for daytime products, and relaxed constraints between surface temperature and air temperature for daytime land scenes. We have integrated these improvements into the ADL framework. This work compares the results from ADL emulation of future IDPS system incorporating all the suggested algorithm updates with the current official processing results by qualitative and quantitative evaluations. The results prove these algorithm updates improve science product quality.

  14. Nontypeable pneumococci can be divided into multiple cps types, including one type expressing the novel gene pspK.

    Science.gov (United States)

    Park, In Ho; Kim, Kyung-Hyo; Andrade, Ana Lucia; Briles, David E; McDaniel, Larry S; Nahm, Moon H

    2012-01-01

    Although virulence of Streptococcus pneumoniae is associated with its capsule, some pathogenic S. pneumoniae isolates lack capsules and are serologically nontypeable (NT). We obtained 64 isolates that were identified as NT "pneumococci" (i.e., bacteria satisfying the conventional definition but without the multilocus sequence typing [MLST]-based definition of S. pneumoniae) by the traditional criteria. All 64 were optochin sensitive and had lytA, and 63 had ply. Twelve isolates had cpsA, suggesting the presence of a conventional but defective capsular polysaccharide synthesis (cps) locus. The 52 cpsA-negative isolates could be divided into three null capsule clades (NCC) based on aliC (aliB-like ORF1), aliD (aliB-like ORF2), and our newly discovered gene, pspK, in their cps loci. pspK encodes a protein with a long alpha-helical region containing an LPxTG motif and a YPT motif known to bind human pIgR. There were nine isolates in NCC1 (pspK(+) but negative for aliC and aliD), 32 isolates in NCC2 (aliC(+) aliD(+) but negative for pspK), and 11 in NCC3 (aliD(+) but negative for aliC and pspK). Among 52 cpsA-negative isolates, 41 were identified as S. pneumoniae by MLST analysis. All NCC1 and most NCC2 isolates were S. pneumoniae, whereas all nine NCC3 and two NCC2 isolates were not S. pneumoniae. Several NCC1 and NCC2 isolates from multiple individuals had identical MLST and cps regions, showing that unencapsulated S. pneumoniae can be infectious among humans. Furthermore, NCC1 and NCC2 S. pneumoniae isolates could colonize mice as well as encapsulated S. pneumoniae, although S. pneumoniae with an artificially disrupted cps locus did not. Moreover, an NCC1 isolate with pspK deletion did not colonize mice, suggesting that pspK is critical for colonization. Thus, PspK may provide pneumococci a means of surviving in the nasopharynx without capsule. IMPORTANCE The presence of a capsule is critical for many pathogenic bacteria, including pneumococci. Reflecting the

  15. The Link between Cognitive Measures and ADLs and IADL Functioning in Mild Alzheimer's: What Has Gender Got to Do with It?

    Directory of Open Access Journals (Sweden)

    James R. Hall

    2011-01-01

    Full Text Available Objectives. To investigate the link between neurocognitive measures and various aspects of daily living (ADL and IADL in women and men with mild Alzheimer's disease (AD. Methods. Participants were 202 AD patients (91 male, 111 female with CDR global scores of ≤1. ADLs and IADLs ratings were obtained from caregivers. Cognitive domains were assessed with neuropsychological testing. Results. Memory and executive functioning were related to IADL scores. Executive functioning was linked to total ADL. Comparisons stratified on gender found attention predicted total ADL score in both men and women. Attention predicted bathing and eating ability in women only. Language predicted IADL functions in men (food preparation and women (driving. Conclusions. Associations between ADLs/IADLs and memory, learning, executive functioning, and language suggest that even in patients with mild AD, basic ADLs require complex cognitive processes. Gender differences in the domains of learning and memory area were found.

  16. Effects of interactive metronome training on upper extremity function, ADL and QOL in stroke patients.

    Science.gov (United States)

    Yu, Ga-Hui; Lee, Jae-Shin; Kim, Su-Kyoung; Cha, Tae-Hyun

    2017-01-01

    Rhythm and timing training is stimulation that substitutes for a damaged function controls muscular movement or temporal element, which has positive impacts on the neurological aspect and movement of the brain. This study is to assess the changes caused by rhythm and timing training using an interactive metronome (IM) on upper extremity function, ADL and QOL in stroke patients. In order to assess the effects of IM training, a group experiment was conducted on 30 stroke patients. Twelve sessions of IM training were provided for the experimental group three times a week for four weeks, while the control group was trained with a Bilateral arm Self-Exercise (BSE) for the same period. Both groups were evaluated by pre- and post-tests through MFT, MAL, K-MBI and SS-QOL. There were more statistically significant differences (<0.05) in the total score of MFT and the finger control item in the IM Group than in the BSE Group. With respect to ADL, there were more statistically significant differences (<0.05) in the total score of K-MBI and the dressing item in the IM Group than in the BSE Group. The study proposes that IM training can be applied as an occupational therapy program in patients with various diseases who need to adjust the time for performing movements as well as stroke patients.

  17. Effects of aquatic PNF lower extremity patterns on balance and ADL of stroke patients.

    Science.gov (United States)

    Kim, Eun-Kyung; Lee, Dong-Kyu; Kim, Young-Mi

    2015-01-01

    [Purpose] This study investigated the effect of aquatic proprioceptive neuromuscular facilitation (PNF) patterns in the lower extremity on balance and activities of daily living (ADL) in stroke patients. [Subjects] Twenty poststroke participants were randomly assigned to an experimental group (n = 10) or a control group (n = 10). The experimental group performed lower extremity patterns in an aquatic environment, and the control group performed lower extremity patterns on the ground. Both exercises were conducted for 30 minutes/day, 5 days/week for 6 weeks. Balance was measured with the Berg Balance Scale (BBS), Timed Up and Go Test (TUGT), Functional Reach Test (FRT), and One Leg Stand Test (OLST). Activities of daily living were measured with the Functional Independence Measure (FIM). A paired t-test was used to measure pre- and post-experiment differences, and an independent t-test was used to measure between-group differences. [Results] The experimental and control groups showed significant differences for all pre- and post-experiment variables. In the between-group comparison, the experimental group was significantly difference from the control group. [Conclusion] These results indicate that performing aquatic proprioceptive neuromuscular facilitation patterns in the lower extremity enhances balance and ADL in stroke patients.

  18. Predicting Child Protective Services (CPS) Involvement among Low-Income U.S. Families with Young Children Receiving Nutritional Assistance.

    Science.gov (United States)

    Slack, Kristen S; Font, Sarah; Maguire-Jack, Kathryn; Berger, Lawrence M

    2017-10-11

    This exploratory study examines combinations of income-tested welfare benefits and earnings, as they relate to the likelihood of child maltreatment investigations among low-income families with young children participating in a nutritional assistance program in one U.S. state (Wisconsin). Using a sample of 1065 parents who received the Special Supplemental Nutrition Assistance Program for Women, Infants, and Children (WIC) benefits in late 2010 and early 2011, we find that relying on either work in the absence of other means-tested welfare benefits, or a combination of work and welfare benefits, reduces the likelihood of CPS involvement compared to parents who rely on welfare benefits in the absence of work. Additionally, we find that housing instability increases the risk of CPS involvement in this population. The findings from this investigation may be useful to programs serving low-income families with young children, as they attempt to identify safety net resources for their clientele.

  19. Exploring the integration of the human as a flexibility factor in CPS enabled manufacturing environments: Methodology and results

    OpenAIRE

    Fantini, P.; Tavola, G.; Taisch, M.; Barbosa, José; Leitão, Paulo; Liu, Y.; Sayed, M.S.; Lohse, N.

    2016-01-01

    Cyber Physical Systems (CPS) are expected to shape the evolution of production towards the fourth industrial revolution named Industry 4.0. The increasing integration of manufacturing processes and the strengthening of the autonomous capabilities of manufacturing systems make investigating the role of humans a primary research objective in view of emerging social and demographic megatrends. Understanding how the employees can be better integrated to enable increased flexibility in manufacturi...

  20. A Personalized QoS Prediction Approach for CPS Service Recommendation Based on Reputation and Location-Aware Collaborative Filtering.

    Science.gov (United States)

    Kuang, Li; Yu, Long; Huang, Lan; Wang, Yin; Ma, Pengju; Li, Chuanbin; Zhu, Yujia

    2018-05-14

    With the rapid development of cyber-physical systems (CPS), building cyber-physical systems with high quality of service (QoS) has become an urgent requirement in both academia and industry. During the procedure of building Cyber-physical systems, it has been found that a large number of functionally equivalent services exist, so it becomes an urgent task to recommend suitable services from the large number of services available in CPS. However, since it is time-consuming, and even impractical, for a single user to invoke all of the services in CPS to experience their QoS, a robust QoS prediction method is needed to predict unknown QoS values. A commonly used method in QoS prediction is collaborative filtering, however, it is hard to deal with the data sparsity and cold start problem, and meanwhile most of the existing methods ignore the data credibility issue. Thence, in order to solve both of these challenging problems, in this paper, we design a framework of QoS prediction for CPS services, and propose a personalized QoS prediction approach based on reputation and location-aware collaborative filtering. Our approach first calculates the reputation of users by using the Dirichlet probability distribution, so as to identify untrusted users and process their unreliable data, and then it digs out the geographic neighborhood in three levels to improve the similarity calculation of users and services. Finally, the data from geographical neighbors of users and services are fused to predict the unknown QoS values. The experiments using real datasets show that our proposed approach outperforms other existing methods in terms of accuracy, efficiency, and robustness.

  1. Arabic translation, cultural adaptation, and validation study of Knee Outcome Survey: Activities of Daily Living Scale (KOS-ADLS).

    Science.gov (United States)

    Algarni, Abdulrahman D; Alrabai, Hamza M; Al-Ahaideb, Abdulaziz; Kachanathu, Shaji John; AlShammari, Sulaiman A

    2017-09-01

    Knee complaints and their accompanying functional impairments are frequent problems encountered by healthcare practitioners worldwide. Plenty of functional scoring systems were developed and validated to give a relative estimation about the knee function. Despite the wide geographic distribution of Arabic language in the Middle East and North Africa, it is rare to find a validated knee function scale in Arabic. The present study is aimed to translate, validate, and culturally adjust the Knee Outcome Survey: Activities of Daily Living Scale (KOS-ADLS) into Arabic language for future use among Arabic-speaking patients. Permission for translation was obtained from the copyrights holder. Two different teams of high-level clinical and linguistic expertise conducted translation process blindly. Forward-backward translation technique was implemented to ensure preservation of the main conceptual content. Main study consisted of 280 subjects. Reliability was examined by test-retest pilot study. Visual Analogue Scale (VAS), Get Up and Go (GUG) Test, Ascending/Descending Stairs (A/D Stairs), and Subjective Assessment of Function (SAF) were conducted concurrently to show the validity of Arabic KOS-ADLS statistically in relation to these scales. Final translated version showed no significant discrepancies. Minor adaptive adjustment was required to fit Arabian cultural background. Internal consistency was favourable (Cronbach's alpha 0.90). Patients' scoring on Arabic KOS-ADLS appeared relatively consistent with their scoring on VAS, GUG, A/D Stairs, and SAF. A significant linear relationship was demonstrated between SAF and total KOS-ADLS scores on regression analysis (adj. R 2  = 0.548). Arabic KOS-ADLS, as its English counterpart, was found to be a simple, valid, and useful instrument for knee function evaluation. Arabic version of KOS-ADLS represents a promising candidate for unconditional use among Arabic-speaking patients with knee complaints.

  2. Long-term declines in ADLs, IADLs, and mobility among older Medicare beneficiaries

    Directory of Open Access Journals (Sweden)

    Wolinsky Fredric D

    2011-08-01

    Full Text Available Abstract Background Most prior studies have focused on short-term (≤ 2 years functional declines. But those studies cannot address aging effects inasmuch as all participants have aged the same amount. Therefore, the authors studied the extent of long-term functional decline in older Medicare beneficiaries who were followed for varying time lengths, and the authors also identified the risk factors associated with those declines. Methods The analytic sample included 5,871 self- or proxy-respondents who had complete baseline and follow-up survey data that could be linked to their Medicare claims for 1993-2007. Functional status was assessed using activities of daily living (ADLs, instrumental ADLs (IADLs, and mobility limitations, with declines defined as the development of two of more new difficulties. Multiple logistic regression analysis was used to focus on the associations involving respondent status, health lifestyle, continuity of care, managed care status, health shocks, and terminal drop. Results The average amount of time between the first and final interviews was 8.0 years. Declines were observed for 36.6% on ADL abilities, 32.3% on IADL abilities, and 30.9% on mobility abilities. Functional decline was more likely to occur when proxy-reports were used, and the effects of baseline function on decline were reduced when proxy-reports were used. Engaging in vigorous physical activity consistently and substantially protected against functional decline, whereas obesity, cigarette smoking, and alcohol consumption were only associated with mobility declines. Post-baseline hospitalizations were the most robust predictors of functional decline, exhibiting a dose-response effect such that the greater the average annual number of hospital episodes, the greater the likelihood of functional status decline. Participants whose final interview preceded their death by one year or less had substantially greater odds of functional status decline

  3. Ambient and smartphone sensor assisted ADL recognition in multi-inhabitant smart environments.

    Science.gov (United States)

    Roy, Nirmalya; Misra, Archan; Cook, Diane

    2016-02-01

    Activity recognition in smart environments is an evolving research problem due to the advancement and proliferation of sensing, monitoring and actuation technologies to make it possible for large scale and real deployment. While activities in smart home are interleaved, complex and volatile; the number of inhabitants in the environment is also dynamic. A key challenge in designing robust smart home activity recognition approaches is to exploit the users' spatiotemporal behavior and location, focus on the availability of multitude of devices capable of providing different dimensions of information and fulfill the underpinning needs for scaling the system beyond a single user or a home environment. In this paper, we propose a hybrid approach for recognizing complex activities of daily living (ADL), that lie in between the two extremes of intensive use of body-worn sensors and the use of ambient sensors. Our approach harnesses the power of simple ambient sensors (e.g., motion sensors) to provide additional 'hidden' context (e.g., room-level location) of an individual, and then combines this context with smartphone-based sensing of micro-level postural/locomotive states. The major novelty is our focus on multi-inhabitant environments, where we show how the use of spatiotemporal constraints along with multitude of data sources can be used to significantly improve the accuracy and computational overhead of traditional activity recognition based approaches such as coupled-hidden Markov models. Experimental results on two separate smart home datasets demonstrate that this approach improves the accuracy of complex ADL classification by over 30 %, compared to pure smartphone-based solutions.

  4. Ambient and smartphone sensor assisted ADL recognition in multi-inhabitant smart environments

    Science.gov (United States)

    Misra, Archan; Cook, Diane

    2016-01-01

    Activity recognition in smart environments is an evolving research problem due to the advancement and proliferation of sensing, monitoring and actuation technologies to make it possible for large scale and real deployment. While activities in smart home are interleaved, complex and volatile; the number of inhabitants in the environment is also dynamic. A key challenge in designing robust smart home activity recognition approaches is to exploit the users' spatiotemporal behavior and location, focus on the availability of multitude of devices capable of providing different dimensions of information and fulfill the underpinning needs for scaling the system beyond a single user or a home environment. In this paper, we propose a hybrid approach for recognizing complex activities of daily living (ADL), that lie in between the two extremes of intensive use of body-worn sensors and the use of ambient sensors. Our approach harnesses the power of simple ambient sensors (e.g., motion sensors) to provide additional ‘hidden’ context (e.g., room-level location) of an individual, and then combines this context with smartphone-based sensing of micro-level postural/locomotive states. The major novelty is our focus on multi-inhabitant environments, where we show how the use of spatiotemporal constraints along with multitude of data sources can be used to significantly improve the accuracy and computational overhead of traditional activity recognition based approaches such as coupled-hidden Markov models. Experimental results on two separate smart home datasets demonstrate that this approach improves the accuracy of complex ADL classification by over 30 %, compared to pure smartphone-based solutions. PMID:27042240

  5. The impact of physical performance and cognitive status on subsequent ADL disability in low-functioning older adults

    NARCIS (Netherlands)

    Kempen, GIJM; Ormel, J

    Objectives. The purpose of this study was to examine the independent contributions of physical performance and cognitive status to subsequent levels of ADL disability in low-functioning non-institutionalized older adults. Methods. A prospective cohort study included 416 women and 141 men 57 years of

  6. The course of apraxia and ADL functioning in left hemisphere stroke patients treated in rehabilitation centres and nursing homes.

    NARCIS (Netherlands)

    Donkervoort, M.; Dekker, J.; Deelman, B.

    2006-01-01

    OBJECTIVE: To study the course of apraxia and daily life functioning (ADL) in left hemisphere stroke patients with apraxia. DESIGN: Prospective cohort study. SETTING: Rehabilitation centres and nursing homes. SUBJECTS: One hundred and eight left hemisphere stroke patients with apraxia, hospitalized

  7. Performance-based assessment of activities of daily living (ADL) ability among women with chronic widespread pain

    DEFF Research Database (Denmark)

    Wæhrens, Eva Elisabet Ejlersen; Amris, Kirstine; Fisher, Anne G

    2010-01-01

    Functional ability, including the ability to perform activities of daily living (ADL), is considered a core outcome domain in chronic pain clinical trials and is usually assessed through generic or disease-specific self-report questionnaires. Research, however, indicates that self...

  8. Effect of Homoeopathic treatment on Activity of Daily Living (ADL in Knee Osteoarthritis: A prospective observational study

    Directory of Open Access Journals (Sweden)

    F F Motiwala

    2016-01-01

    Full Text Available Objectives: To investigate the effect of individualized homoeopathic medicines in improving ADL by reducing pain, stiffness and limiting the disease progress. Materials and Methods: 131 consecutive patients with OA of knee were recruited and followed up for minimum period of twelve months. Two orthopaedic surgeons diagnosed the disease based on clinical examination of the patients. Three trained homoeopathic physicians prescribed individualized homoeopathic simillimum and the patients were evaluated for pain on WOMAC Osteoarthritis Index LK3.1 (IK survey form measuring pain, stiffness and ADL. The pain was also measured on Numerical pain rating scale for confirmation. Result: Individualized homoeopathic medicines prescribed as per law of similia improved the mean ADL from 35.85 to 19.08 (p- 0.0001. Mean pain on WOMAC Osteoarthritis Index survey form improved from 10.50 to 5.48 (p-0.0001. The mean pain score on NRS improved from 6.34 to 3.77 (p-0.0001 and the mean morning stiffness also improved from 4.55 to 2.18 (p-0.0001. Conclusion: Homoeopathic medicines have potential to improve the ADL of OA patients by reducing pain and stiffness and limiting progress of the disease without any adverse systemic effects and can safely be employed as a comprehensive health care therapeutics.

  9. Biochemical Characterization of CPS-1, a Subclass B3 Metallo-β-Lactamase from a Chryseobacterium piscium Soil Isolate

    DEFF Research Database (Denmark)

    Gudeta, Dereje Dadi; Pollini, Simona; Docquier, Jean-Denis

    2016-01-01

    CPS-1 is a subclass B3 metallo-β-lactamase from a Chryseobacterium piscium isolated from soil, showing 68 % amino acid identity to GOB-1 enzyme. CPS-1 was overproduced in Escherichia coli Rosetta (DE3), purified by chromatography and biochemically characterized. This enzyme exhibits a broad spect...... spectrum substrate profile including penicillins, cephalosporins and carbapenems, which overall resembles those of L1, GOB-1 and acquired subclass B3 enzymes AIM-1 and SMB-1....

  10. Quantitation of stress/rest 201TI SPECT of the legs in the diagnosis of compartment-NT syndromes (CPS)

    International Nuclear Information System (INIS)

    Hayes, A.A.; Bower, G.D.; Pitstock, K.L.; Maguire, K.F.

    1998-01-01

    Full text: Compartment-NT syndrom (CPS) of the legs is considered to have an ischaemic basis related to muscle swelling and pressure increase in a muscle compartment (MC) during isotonic work. We decided to study selected patients where CPS was suspected with exercise 201 TI SPECT of the legs to better define their diagnoses. Eighteen patients with probable CPS reproduced their leg pain(s) during isotonic work, and 100 MBq of 201 TI was given i.v. during continued work and pain. Anterior 300 sec. planar and 360 degree, elliptical SPECT studies were acquired five minutes after stress and again four hours later. Quantitation of whole calf and regional MC uptake was attempted after the first five patients were assessed qualitatively. Ten patients were men and eight were women. The mean age was 30.8 y. Four had localised posterior and three had anterior pain with 11 having mixed and bilateral symptoms. Five patients had had a bone scan in the past and nine had MC pressure studies done within a month of study. Six patients had had previous decompressive surgery and seven patients had surgery after stress/rest studies. Four asymptomatic cardiac patients (''controls'') were imaged after their cardiac 201 TI studies and data used for comparison. Mean age of controls was 33 years. Generally even muscle uptake was seen on stress images with mean washout of 201 TI of 12% (7-23%) being calculated on delayed images of controls. Painful MCs with qualitative reduction in uptake after stress showed a mean increase in 201 TI of 25.7% (6-39%) on delayed imaging. Three patients with dramatic improvement in symptoms after surgery had shown a mean increase of 25.2% in delayed uptake in MCs on pre-operative studies. One patient showed washout of 11 and 15% from posterior MCs and had a poor response to subsequent surgery. Further clinical follow up in a large group of patients will be required to fully identify the place of Stress 201 TI imaging of the legs in this difficult group of

  11. E-cigarette use and smoking reduction or cessation in the 2010/2011 TUS-CPS longitudinal cohort

    OpenAIRE

    Yuyan Shi; John P. Pierce; Martha White; Maya Vijayaraghavan; Wilson Compton; Kevin Conway; Anne M. Hartman; Karen Messer

    2016-01-01

    Abstract Background Electronic cigarettes (e-cigarettes) are heavily marketed and widely perceived as helpful for quitting or reducing smoking intensity. We test whether ever-use of e-cigarettes among early adopters was associated with: 1) increased cigarette smoking cessation; and 2) reduced cigarette consumption. Methods A representative cohort of U.S. smokers (N = 2454) from the 2010 Tobacco Use Supplement to the Current Population Survey (TUS-CPS) was re-interviewed 1 year later. Outcomes...

  12. High-energy coordination polymers (CPs) exhibiting good catalytic effect on the thermal decomposition of ammonium dinitramide

    Science.gov (United States)

    Li, Xin; Han, Jing; Zhang, Sheng; Zhai, Lianjie; Wang, Bozhou; Yang, Qi; Wei, Qing; Xie, Gang; Chen, Sanping; Gao, Shengli

    2017-09-01

    High-energy coordination polymers (CPs) not only exhibit good energetic performances but also have a good catalytic effect on the thermal decomposition of energetic materials. In this contribution, two high-energy CPs Cu2(DNBT)2(CH3OH)(H2O)3·3H2O (1) and [Cu3(DDT)2(H2O)2]n (2) (H2DNBT = 3,3‧-dinitro-5,5‧-bis(1H-1,2,4-triazole and H3DDT = 4,5-bis(1H-tetrazol-5-yl)-2H-1,2,3-triazole) were synthesized and structurally characterized. Furthermore, 1 was thermos-dehydrated to produce Cu2(DNBT)2(CH3OH)(H2O)3 (1a). The thermal decomposition kinetics of 1, 1a and 2 were studied by Kissinger's method and Ozawa's method. Thermal analyses and sensitivity tests show that all compounds exhibit high thermal stability and low sensitivity for external stimuli. Meanwhile, all compounds have large positive enthalpy of formation, which are calculated as being (1067.67 ± 2.62) kJ mol-1 (1), (1464.12 ± 3.12) kJ mol-1 (1a) and (3877.82 ± 2.75) kJ mol-1 (2), respectively. The catalytic effects of 1a and 2 on the thermal decomposition of ammonium dinitramide (ADN) were also investigated.

  13. Cost-effectiveness evaluation of clobetasol propionate shampoo (CPS) maintenance in patients with moderate scalp psoriasis: a Pan-European analysis.

    Science.gov (United States)

    Papp, K; Poulin, Y; Barber, K; Lynde, C; Prinz, J C; Berg, M; Kerrouche, N; Rives, V P

    2012-11-01

    Scalp psoriasis is a difficult to treat and usually chronic manifestation of psoriasis. The CalePso study showed that CPS (Clobex(®) Shampoo) in maintenance therapy of scalp psoriasis (twice weekly) significantly increases the probability of keeping patient under remission during 6 months, compared with vehicle (40.3% relapses vs. 11.6% relapses, ITT). The objective of the study was to assess the cost-effectiveness of a maintenance therapy with CPS vs. its vehicle in nine European countries. A 24-week decision tree model was developed with 4-weekly time steps. The considered population has moderate scalp psoriasis successfully treated with a daily application of CPS up to 4 weeks. Data were taken from the CalePso study and from national experts' recommendations for alternative treatment choices, with their probabilities of success taken from literature to develop country-specific models. Health benefits are measured in disease-free days (DFD). The economic analysis includes drug and physician costs. A probabilistic sensitivity analysis (PrSA) assesses the uncertainty of the model. Depending on the country, the mean total number of DFDs per patient is 21-42% higher with CPS compared with vehicle, and the mean total cost is 11-31% lower. The mean costs per DFD are 30-46% lower with CPS compared with the vehicle. The PrSA showed in 1000 simulations that CPS is more effective vs. vehicle in 100% of the cases and less expensive than its vehicle in 80-99% of the cases. This model suggests that CPS is cost-effective in maintaining the success achieved in moderate scalp psoriasis patients. © 2011 The Authors. Journal of the European Academy of Dermatology and Venereology © 2011 European Academy of Dermatology and Venereology.

  14. The Classroom Performance System (CPS): Effects on student participation, attendance, and achievement in multicultural anatomy and physiology classes at South Texas College

    Science.gov (United States)

    Termos, Mohamad Hani

    2011-12-01

    The Classroom Performance System (CPS) is an instructional technology tool that increases student performance and addresses different learning styles. Instructional technologies are used to promote active learning; however, student embarrassment issue in a multicultural setting is not addressed. This study assessed the effect of the CPS on student participation, attendance, and achievement in multicultural college-level anatomy and physiology classes at South Texas College, where the first spoken language is not English. Quantitative method and quasi-experimental design were employed and comparative statistic methods and pre-post tests were used to collect the data. Participants were college students and sections of study were selected by convenient sampling. Participation was 100% during most of the lectures held and participation rate did not strike above 68% in control group. Attendance was significantly higher in CPS sections than the control group as shown by t-tests. Experimental sections had a higher increase in the pre-post test scores and student averages on lecture exams increased at a higher rate as compared to the control group. Therefore, the CPS increased student participation, attendance, and achievement in multicultural anatomy and physiology classes. The CPS can be studied in other settings where the first spoken language is English or in other programs, such as special education programs. Additionally, other variables can be studied and other methodologies can be employed.

  15. Crystallization and preliminary crystallographic analysis of the bacterial capsule assembly-regulating tyrosine phosphatases Wzb of Escherichia coli and Cps4B of Streptococcus pneumoniae

    International Nuclear Information System (INIS)

    Huang, Hexian; Hagelueken, Gregor; Whitfield, Chris; Naismith, James H.

    2009-01-01

    The crystallization is reported of two bacterial tyrosine phosphatases which belong to different enzyme families despite their ability to catalyse identical reactions. Bacterial tyrosine kinases and their cognate phosphatases are key players in the regulation of capsule assembly and thus are important virulence determinants of these bacteria. Examples of the kinase/phosphatase pairing are found in Gram-negative bacteria such as Escherichia coli (Wzc and Wzb) and in Gram-positive bacteria such as Streptococcus pneumoniae (CpsCD and CpsB). Although Wzb and Cps4B are both predicted to dephosphorylate the C-terminal tyrosine cluster of their cognate tyrosine kinase, they appear on the basis of protein sequence to belong to quite different enzyme classes. Recombinant purified proteins Cps4B of S. pneumoniae TIGR4 and Wzb of E. coli K-30 have been crystallized. Wzb crystals belonged to space-group family P3 x 21 and diffracted to 2.7 Å resolution. Crystal form I of Cps4B belonged to space-group family P4 x 2 1 2 and diffracted to 2.8 Å resolution; crystal form II belonged to space group P2 1 2 1 2 1 and diffracted to 1.9 Å resolution

  16. Associations between results of post-stroke NDT-Bobath rehabilitation in gait parameters, ADL and hand functions.

    Science.gov (United States)

    Mikołajewska, Emilia

    2013-01-01

    In patients after a stroke there are variable disorders. These patients often need rehabilitation in more than one area beceause of multiple limitations of the ability to perform everyday activities. The aim of the study was to assess correlations - statistical relationships between observed gait parameters, ADL and hand functions - results of rehabilitation of patients after ischaemic stroke according to the NDTBobath method for adults. The investigated group consisted of 60 patients after ischaemic stroke, who participated in the rehabilitation programme. 10 sessions of the NDT-Bobath therapy were provided in 2 weeks (10 days of the therapy). The calculation of correlations was made based on changes of parameters: Bobath Scale (to assess hand functions), Barthel Index (to assess ADL), gait velocity, cadence and stride lenght. Measurements were performed in every patient twice: on admission (before the therapy) and after last session of the therapy to assess rehabilitation effects. The main statistically relevant corellations observed in the study were as follows: in the whole group of patients: poor and moderate (negative) correlation between changes of gait parameters and Bobath Scale and Barthel Index, moderate and severe (negative) correlation between changes of gait parameters and Bobath Scale and Barthel Index in the group of women, correlation between changes in Bobath Scale and Barthel Index in the group of patients with left side of paresis, (negative) correlation between changes of gait parameters and Bobath Scale in group of patients younger than 68 years, moderate, high and very high correlations between changes in gait parameters in groups of women, men, younger than 68 years and older than 68 years. There have been observed statistically significant and favourable changes in the health status of patients, described by gait parameters, changes in hand functions and ADL. Based on the presented correlations there is an assumption that it is hard to

  17. Older Asian Americans and Pacific Islanders with Activities of Daily Living (ADL Limitations: Immigration and Other Factors Associated with Institutionalization

    Directory of Open Access Journals (Sweden)

    Esme Fuller-Thomson

    2012-09-01

    Full Text Available This study determined the national prevalence and profile of Asian Americans with Activities of Daily Living (ADL limitations and identified factors associated with institutionalization. Data were obtained from 2006 American Community Survey, which replaced the long-form of the US Census. The data are nationally representative of both institutionalized and community-dwelling older adults. Respondents were Vietnamese (n = 203, Korean (n = 131, Japanese (n = 193, Filipino (n = 309, Asian Indian (n = 169, Chinese (n = 404, Hawaiian/Pacific Islander (n = 54, and non-Hispanic whites (n = 55,040 aged 55 and over who all had ADL limitations. The prevalence of institutionalized among those with ADL limitations varies substantially from 4.7% of Asian Indians to 18.8% of Korean Americans with ADL limitations. Every AAPI group had a lower prevalence of institutionalization than disabled Non-Hispanic whites older adults (23.8% (p < 0.001. After adjustment for socio-demographic characteristics, Asian Indians, Vietnamese, Japanese, Filipino, and Chinese had significantly lower odds of institutionalization than non-Hispanic whites (OR = 0.29, 0.31, 0.58, 0.51, 0.70, respectively. When the sample was restricted to AAPIs, the odds of institutionalization were higher among those who were older, unmarried, cognitively impaired and those who spoke English at home. This variation suggests that aggregating data across the AAPI groups obscures meaningful differences among these subpopulations and substantial inter-group differences may have important implications in the long-term care setting.

  18. Item-level psychometrics of the ADL instrument of the Korean National Survey on persons with physical disabilities.

    Science.gov (United States)

    Hong, Ickpyo; Lee, Mi Jung; Kim, Moon Young; Park, Hae Yean

    2017-10-01

    The aim of this study is to investigate the psychometrics of the 12 items of an instrument assessing activities of daily living (ADL) using an item response theory model. A total of 648 adults with physical disabilities and having difficulties in ADLs were retrieved from the 2014 Korean National Survey on People with Disabilities. The psychometric testing included factor analysis, internal consistency, precision, and differential item functioning (DIF) across categories including sex, older age, marital status, and physical impairment area. The sample had a mean age of 69.7 years old (SD = 13.7). The majority of the sample had lower extremity impairments (62.0%) and had at least 2.1 chronic conditions. The instrument demonstrated unidimensional construct and good internal consistency (Cronbach's alpha = 0.95). The instrument precisely estimated person measures within a wide range of theta values (-2.22 logits  5.0%). Our findings indicate that the dressing item would need to be modified to improve its psychometrics. Overall, the ADL instrument demonstrates good psychometrics, and thus, it may be used as a standardized instrument for measuring disability in rehabilitation contexts. However, the findings are limited to adults with physical disabilities. Future studies should replicate psychometric testing for survey respondents with other disorders and for children.

  19. The effect of gamma irradiation on crude fibre NDF, ADF, and ADL of some Syrian agricultural residues

    International Nuclear Information System (INIS)

    Al-Masri, M.R.; Zarkawi, M.

    1992-07-01

    The effects of 150 KGy of gamma irradiation on crude fibre and its main components (cellulose, hemicellulose-cellulose and lignin) and on neutral detergent fibre (NDF), acid detergent lignin (ADL), and acid detergent fibre (ADF) were investigated. The results indicate that gamma irradiation decreased Cf content by 30%, 28%, 29%, and 17% for cottonwood, lentils straw, apple-tree pruning products and olive-oil cake, respectively. NDF values also decreased by 5%, 23%, 13% and 3% for, cottonwood, lentils straw, olive-oil cake and apple-tree pruning products respectively. Gamma irradiation (150 KGy) had no effects on ADF and ADL for lentils straw, apple-tree pruning products and olive-oil cake whereas, ADF decreased by 8.5% and ADL by 8.3 for cottonwood. Hemicellulose content increased by 12% for cottonwood while decreased by 54% for lentils straw and by 33% for apple-tree pruning products with no effects for olive-oil cake. Cellulose content decreased by 8.6% for cottonwood whereas no effects for the remaining residues were seen. Gamma irradiation treatment improved the nutritive value of the agriculture residues examined. The reduction in crude fibre content varies with the residue. (author). 15 refs., 5 tabs

  20. THE EFFECT OF SOIL CONDITIONERS ON CELLULOSE, HEMICELLULOSE, AND THE ADL FIBRE FRACTION CONCENTRATION IN DACTYLIS GLOMERATA AND LOLIUM PERENNE

    Directory of Open Access Journals (Sweden)

    Milena Truba

    2017-01-01

    Full Text Available Replicated three times, the research was conducted in the experimental field between 2011 and 2014. Three soil conditioners with the following trade names: UGmax, Eko-Użyźniacz, and Humus Active Papka were used in the experiment, separately or together with NPK fertilisers. They were all used on plots sown with two species of grass, Dactylis glomerata of the Bora variety and Lolium perenne of the Info variety. The plant material from both grass species was tested for the concentration of ADL fraction (% DM, cellulose (% DM, and hemicellulose (% DM. It was found that the concentration of cellulose, hemicelluloses, and the ADL fraction was significantly higher in the biomass of Dactylis glomerata than in the biomass of Lolium perenne. The grass from the plot with the UGmax soil conditioner applied had the highest amount of cellulose and hemicellulose. The lowest amount of those organic compounds was found in the grass treated with UGmax together with mineral fertilisers and in plants treated with Humus Active, together with mineral fertilisers. However, the fertilisers and conditioners did not increase the ADL content in both grass species.

  1. Estimating the number of components and detecting outliers using Angle Distribution of Loading Subspaces (ADLS) in PCA analysis.

    Science.gov (United States)

    Liu, Y J; Tran, T; Postma, G; Buydens, L M C; Jansen, J

    2018-08-22

    Principal Component Analysis (PCA) is widely used in analytical chemistry, to reduce the dimensionality of a multivariate data set in a few Principal Components (PCs) that summarize the predominant patterns in the data. An accurate estimate of the number of PCs is indispensable to provide meaningful interpretations and extract useful information. We show how existing estimates for the number of PCs may fall short for datasets with considerable coherence, noise or outlier presence. We present here how Angle Distribution of the Loading Subspaces (ADLS) can be used to estimate the number of PCs based on the variability of loading subspace across bootstrap resamples. Based on comprehensive comparisons with other well-known methods applied on simulated dataset, we show that ADLS (1) may quantify the stability of a PCA model with several numbers of PCs simultaneously; (2) better estimate the appropriate number of PCs when compared with the cross-validation and scree plot methods, specifically for coherent data, and (3) facilitate integrated outlier detection, which we introduce in this manuscript. We, in addition, demonstrate how the analysis of different types of real-life spectroscopic datasets may benefit from these advantages of ADLS. Copyright © 2018 The Authors. Published by Elsevier B.V. All rights reserved.

  2. Cross-cultural adaptation of the Greek version of the Knee Outcome Survey--activities of Daily Living Scale (KOS-ADLS).

    Science.gov (United States)

    Kapreli, E; Panelli, G; Strimpakos, N; Billis, E; Zacharopoulos, A; Athanasopoulos, S

    2011-12-01

    The purpose of this study was to cross-culturally adapt and validate the Greek version of Knee Outcome Survey-Activities of Daily Living Scale (KOS-ADLS), a self-reported instrument used for patients with various knee pathological conditions including osteoarthritis. Ninety-four patients (57 males and 37 females) with a variety of pathological knee disorders and impairments being referred to physical therapy for evaluation and treatment were included in the study. For the crοss-cultural translation, a back-translation procedure was utilized by 3 bi-lingual translators. To assess test-retest reliability the patients were asked to complete the KOS-ADLS twice at initial visit; before and after physiotherapy treatment. To assess responsiveness, patients completed the KOS-ADLS at the end of all physiotherapy sessions and the score was compared with KOS-ADLS at initial (pre-treatment) visit. Finally, concurrent validity was measured by comparing the responses to the KOS-ADLS scores against the scores obtained from Visual Analogue Scale (VAS) and Global Rating Scale (GRS). Reliability was found satisfactory (ICC=0.97; SEM=3.03; SDD=23.05; Cronbach's alpha=0.98). Moreover, a gender subgroup analysis showed that women were more reliable than men. Minor floor/ceiling effects were detected. Concerning validity, all correlations were statistically significant, ranging from r=0.315 to r=0.741, however GRS presented higher correlations with KOS-ADLS in comparison with VAS. Finally, Greek KOS-ADLS was able to detect changes over time (standardized effect size=1.31 and standardized response mean=1.64). The Greek version of KOS-ADLS was found to be reliable, valid, responsive and comprehensible to use with patients with knee pathology. Copyright © 2010 Elsevier B.V. All rights reserved.

  3. The Effects of the Green House Nursing Home Model on ADL Function Trajectory: A Retrospective Longitudinal Study

    Science.gov (United States)

    YOON, Ju Young; BROWN, Roger L.; BOWERS, Barbara J.; SHARKEY, Siobhan S.; HORN, Susan D.

    2015-01-01

    Background Growing attention in the past few decades has focused on improving care quality and quality of life for nursing home residents. Many traditional nursing homes have attempted to transform themselves to become more homelike emphasizing individualized care. This trend is referred to as nursing home culture change in the U.S. A promising culture change nursing home model, the Green House (GH) nursing home model, has shown positive psychological outcomes. However, little is known about whether the GH nursing home model has positive effects on physical function compared to traditional nursing homes. Objectives To examine the longitudinal effects of the GH nursing home model by comparing change patterns of ADL function over time between GH home residents and traditional nursing home residents. Design A retrospective longitudinal study. Settings Four GH organizations (nine GH units and four traditional units). Participants A total of 242 residents (93 GH residents and 149 traditional home residents) who had stayed in the nursing home at least six months from admission. Methods The outcome was ADL function, and the main independent variable was the facility type in which the resident stayed: a GH or traditional unit. Age, gender, comorbidity score, cognitive function, and depressive symptoms at baseline were controlled. All of these measures were from a minimum dataset. Growth curve modeling and growth mixture modeling were employed in this study for longitudinal analyses. Results The mean ADL function showed deterioration over time, and the rates of deterioration between GH and traditional home residents were not different over time. Four different ADL function trajectories were identified for 18 months, but there was no statistical difference in the likelihood of being in one of the four trajectory classes between the two groups. Conclusions Although GH nursing homes are considered to represent an innovative model changing the nursing home environment into more

  4. Utility of the CPS+EG staging system in hormone receptor-positive, human epidermal growth factor receptor 2-negative breast cancer treated with neoadjuvant chemotherapy.

    Science.gov (United States)

    Marmé, Frederik; Lederer, Bianca; Blohmer, Jens-Uwe; Costa, Serban Dan; Denkert, Carsten; Eidtmann, Holger; Gerber, Bernd; Hanusch, Claus; Hilfrich, Jörn; Huober, Jens; Jackisch, Christian; Kümmel, Sherko; Loibl, Sibylle; Paepke, Stefan; Untch, Michael; von Minckwitz, Gunter; Schneeweiss, Andreas

    2016-01-01

    Pathologic complete response after neoadjuvant chemotherapy (NACT) correlates with overall survival (OS) in primary breast cancer. A recently described staging system based on pre-treatment clinical stage (CS), final pathological stage (PS), estrogen receptor (ER) status and nuclear grade (NG) leads to a refined estimation of prognosis in unselected patients. Its performance in luminal type breast cancers has not been determined. This study investigates the clinical utility of this CPS+EG score when restricted to hormone receptor-positive (HR+)/human epidermal growth factor receptor 2-negative (HER2-) patients and compares the results to a cohort of unselected patients. The CPS+EG score was calculated for 6637 unselected patients and 2454 patients with HR+/HER2- tumours who received anthracycline/taxane-based NACT within 8 prospective German trials. Five-year disease-free survival (DFS) and OS were 75.6% and 84.1% for the unselected cohort and 80.6% and 87.8% for the HR+/HER2- subgroup, respectively. The CPS+EG system distinguished different prognostic groups with 5-year DFS ranging from 0% to 91%. The CPS+EG system leads to an improved categorisation of patients by outcome compared to CS, PS, ER or NG alone. When applying the CPS+EG score to the HR+/HER2- subgroup, a shift to lower scores was observed compared to the overall population, but 5-year DFS and OS for the individual scores were identical to that observed in the overall population. In HR+/HER2- patients, the CPS+EG staging system retains its ability to facilitate a refined stratification of patients according to outcome. It can help to select candidates for post-neoadjuvant clinical trials in luminal breast cancer. Copyright © 2015 Elsevier Ltd. All rights reserved.

  5. [Influence of high fall-related self-efficacy on falls due to dissociation with ADL among elderly women in nursing homes].

    Science.gov (United States)

    Kato, Chikako; Ida, Kunio; Harada, Atsushi

    2009-09-01

    We examined the influence of high fall-related self-efficacy on falls due to dissociation with activities of daily living (ADL) among elderly women in nursing homes. We enrolled 72 female nursing home residents who were 70 years old or over and who scored 18 or higher on the Mini-Mental State Examination (MMSE). Subjects were classified into three groups based on the relationship between ADL and fall-related self-efficacy derived from a scattergram of the Functional Independence Measure (FIM) motor items and Falls Efficacy Scale (FES). The three groups were: group I which had low ADL and high fall-related self-efficacy (n=25); group II which had high ADL and low fall-related self-efficacy (n=30); and group III which had a correlation of ADL and fall-related self-efficacy in the 95% confidence interval (n=17). Then, we investigated the incidence of falls and the number of falls after 6 months in the three groups. The risk factor of falls was also investigated using multiple logistic regression analysis. The incidence and number of falls were significantly different in the three groups after 6 months. Moreover, the incidence of those falling was significantly different between group I and group III. The occurrence of falls was also significantly related with a past history of falls, FES, and group I which had low ADL and high fall-related self-efficacy. These findings suggest that the risk of falling increases in the presence of excessive fall-related self-efficacy dissociated from ADL.

  6. Effects of inpatient geriatric interventions in a German geriatric hospital: Impact on ADL, mobility and cognitive status.

    Science.gov (United States)

    Bordne, S; Schulz, R-J; Zank, S

    2015-06-01

    Given the demographic changes, the need for effective geriatric intervention is obvious. Geriatric care aims to maintain the highest possible level of independence and quality of life and to reduce the risk of need for care. This study investigated the benefits of geriatric care on functional performance, mobility and cognition. This study involved a retrospective analysis of clinical data from 646 patients. At hospital admission and discharge functional status was assessed using the Barthel index. Mobility was evaluated by means of the Tinetti test and cognition by the mini-mental state examination (MMSE). A follow-up was conducted on 112 patients 2-5 months after hospital discharge. Statistical analysis included t-tests including Cohen's d for effect size and multivariate regression analysis. The mean age of the study population was 81.1 ± 7.1 years including 439 women (68%) and 207 men (32%). There were significant average improvements for activities of daily living (ADL), mobility and cognition comparing discharge and admission scores. For functional and mobility status, effect sizes were medium to high. Regression analyses showed that ADL improvement was predicted by functional, mobile and cognitive status at admission. Follow-up analyses revealed a high percentage of former patients still living at home and an overall maintenance of ADL levels. Geriatric patients seem to experience long-term improvements during geriatric treatment, which appears to fulfill its aim of recovering independence. For a better understanding of relevant factors for the recreation of geriatric patients, further research is needed, e.g. with respect to the impact of the nutritional status.

  7. Restrictions and satisfaction with participation in patients who are ADL-independent after an aneurysmal subarachnoid hemorrhage.

    Science.gov (United States)

    Huenges Wajer, Irene M C; Visser-Meily, Johanna M A; Greebe, Paut; Post, Marcel W M; Rinkel, Gabriel J E; van Zandvoort, Martine J E

    2017-03-01

    Most survivors of an aneurysmal subarachnoid hemorrhage (aSAH) are ADL-independent, but they often experience restrictions in (social) activities and, therefore, cannot regain their pre-morbid level of participation. In this study, participation restrictions and participation satisfaction experienced after aSAH were assessed. Moreover, possible predictors of participation after aSAH were examined to identify goals for rehabilitation. Participation restrictions experienced by a series of 67 patients visiting our SAH outpatient clinic were assessed as part of standard clinical care using the Participation Restrictions and Satisfaction sections of the Utrecht Scale for Evaluation of Rehabilitation Participation (USER-Participation) 6 months after aSAH. Cognitive impairments, cognitive and emotional complaints, and symptoms of depression and anxiety, assessed 10 weeks after aSAH, were examined as possible predictors of participation by means of linear regression analysis. Although patients were ADL-independent, 64% reported one or more participation restrictions and 60% were dissatisfied in one or more participation domains. Most commonly experienced restrictions concerned housekeeping, chores in and around the house, and physical exercise. Dissatisfaction was most often reported about outdoor activities, mobility, and work/housekeeping. The main predictors of participation restrictions as well as satisfaction with participation were cognitive complaints (subjective) (β = -.30, p = .03 and β = -.40, p = .002, respectively) and anxiety (β = .32, p = .02 and β = -.34, p = .007, respectively). Almost two-thirds of the ADL-independent patients experienced problems of participation 6 months after aSAH. Cognitive complaints (subjective) and anxiety symptoms showed the strongest association with participation restrictions and satisfaction. Cognitive rehabilitation and anxiety-reducing interventions may help to optimize rehabilitation and increase

  8. Measurement Equivalence in ADL and IADL Difficulty Across International Surveys of Aging: Findings From the HRS, SHARE, and ELSA

    Science.gov (United States)

    Kasper, Judith D.; Brandt, Jason; Pezzin, Liliana E.

    2012-01-01

    Objective. To examine the measurement equivalence of items on disability across three international surveys of aging. Method. Data for persons aged 65 and older were drawn from the Health and Retirement Survey (HRS, n = 10,905), English Longitudinal Study of Aging (ELSA, n = 5,437), and Survey of Health, Ageing and Retirement in Europe (SHARE, n = 13,408). Differential item functioning (DIF) was assessed using item response theory (IRT) methods for activities of daily living (ADL) and instrumental activities of daily living (IADL) items. Results. HRS and SHARE exhibited measurement equivalence, but 6 of 11 items in ELSA demonstrated meaningful DIF. At the scale level, this item-level DIF affected scores reflecting greater disability. IRT methods also spread out score distributions and shifted scores higher (toward greater disability). Results for mean disability differences by demographic characteristics, using original and DIF-adjusted scores, were the same overall but differed for some subgroup comparisons involving ELSA. Discussion. Testing and adjusting for DIF is one means of minimizing measurement error in cross-national survey comparisons. IRT methods were used to evaluate potential measurement bias in disability comparisons across three international surveys of aging. The analysis also suggested DIF was mitigated for scales including both ADL and IADL and that summary indexes (counts of limitations) likely underestimate mean disability in these international populations. PMID:22156662

  9. Genome-Wide Analysis of Seed Acid Detergent Lignin (ADL) and Hull Content in Rapeseed (Brassica napus L.)

    Science.gov (United States)

    Wei, Lijuan; Qu, Cunmin; Xu, Xinfu; Lu, Kun; Qian, Wei; Li, Jiana; Li, Maoteng; Liu, Liezhao

    2015-01-01

    A stable yellow-seeded variety is the breeding goal for obtaining the ideal rapeseed (Brassica napus L.) plant, and the amount of acid detergent lignin (ADL) in the seeds and the hull content (HC) are often used as yellow-seeded rapeseed screening indices. In this study, a genome-wide association analysis of 520 accessions was performed using the Q + K model with a total of 31,839 single-nucleotide polymorphism (SNP) sites. As a result, three significant associations on the B. napus chromosomes A05, A09, and C05 were detected for seed ADL content. The peak SNPs were within 9.27, 14.22, and 20.86 kb of the key genes BnaA.PAL4, BnaA.CAD2/BnaA.CAD3, and BnaC.CCR1, respectively. Further analyses were performed on the major locus of A05, which was also detected in the seed HC examination. A comparison of our genome-wide association study (GWAS) results and previous linkage mappings revealed a common chromosomal region on A09, which indicates that GWAS can be used as a powerful complementary strategy for dissecting complex traits in B. napus. Genomic selection (GS) utilizing the significant SNP markers based on the GWAS results exhibited increased predictive ability, indicating that the predictive ability of a given model can be substantially improved by using GWAS and GS. PMID:26673885

  10. Exploring the prevalence and variance of cognitive impairment, pain, neuropsychiatric symptoms and ADL dependency among persons living in nursing homes; a cross-sectional study.

    Science.gov (United States)

    Björk, Sabine; Juthberg, Christina; Lindkvist, Marie; Wimo, Anders; Sandman, Per-Olof; Winblad, Bengt; Edvardsson, David

    2016-08-22

    Earlier studies in nursing homes show a high prevalence of cognitive impairment, dependency in activities of daily living (ADL), pain, and neuropsychiatric symptoms among residents. The aim of this study was to explore the prevalence of the above among residents in a nationally representative sample of Swedish nursing homes, and to investigate whether pain and neuropsychiatric symptoms differ in relation to gender, cognitive function, ADL-capacity, type of nursing-home unit and length of stay. Cross-sectional data from 188 randomly selected nursing homes were collected. A total of 4831 residents were assessed for cognitive and ADL function, pain and neuropsychiatric symptoms. Data were analysed using descriptive statistics and the chi-square test. The results show the following: the prevalence of cognitive impairment was 67 %, 56 % of residents were ADL-dependent, 48 % exhibited pain and 92 % exhibited neuropsychiatric symptoms. The prevalence of pain did not differ significantly between male and female residents, but pain was more prevalent among cognitively impaired and ADL-dependent residents. Pain prevalence was not significantly different between residents in special care units for people with dementia (SCU) and general units, or between shorter-and longer-stay residents. Furthermore, the prevalence of neuropsychiatric symptoms did not differ significantly between male and female residents, between ADL capacities or in relation to length of stay. However, residents with cognitive impairment and residents in SCUs had a significantly higher prevalence of neuropsychiatric symptoms than residents without cognitive impairment and residents in general units. The prevalence rates ascertained in this study could contribute to a greater understanding of the needs of nursing-home residents, and may provide nursing home staff and managers with trustworthy assessment scales and benchmark values for further quality assessment purposes, clinical development work and

  11. E-cigarette use and smoking reduction or cessation in the 2010/2011 TUS-CPS longitudinal cohort

    Directory of Open Access Journals (Sweden)

    Yuyan Shi

    2016-10-01

    Full Text Available Abstract Background Electronic cigarettes (e-cigarettes are heavily marketed and widely perceived as helpful for quitting or reducing smoking intensity. We test whether ever-use of e-cigarettes among early adopters was associated with: 1 increased cigarette smoking cessation; and 2 reduced cigarette consumption. Methods A representative cohort of U.S. smokers (N = 2454 from the 2010 Tobacco Use Supplement to the Current Population Survey (TUS-CPS was re-interviewed 1 year later. Outcomes were smoking cessation for 30+ days and change in cigarette consumption at follow-up. E-cigarettes use was categorized as for cessation purposes or for another reason. Multivariate regression was used to adjust for demographics and baseline cigarette dependence level. Results In 2011, an estimated 12 % of adult U.S. smokers had ever used e-cigarettes, and 41 % of these reported use to help quit smoking. Smokers who had used e-cigarettes for cessation were less likely to be quit for 30+ days at follow-up, compared to never-users who tried to quit (11.1 % vs 21.6 %; ORadj = 0.44, 95 % CI = 0.2–0.8. Among heavier smokers at baseline (15+ cigarettes per day (CPD, ever-use of e-cigarettes was not associated with change in smoking consumption. Lighter smokers (<15 CPD who had ever used e-cigarettes for quitting had stable consumption, while increased consumption was observed among all other lighter smokers, although this difference was not statistically significant. Conclusions Among early adopters, ever-use of first generation e-cigarettes to aid quitting cigarette smoking was not associated with improved cessation or with reduced consumption, even among heavier smokers.

  12. E-cigarette use and smoking reduction or cessation in the 2010/2011 TUS-CPS longitudinal cohort.

    Science.gov (United States)

    Shi, Yuyan; Pierce, John P; White, Martha; Vijayaraghavan, Maya; Compton, Wilson; Conway, Kevin; Hartman, Anne M; Messer, Karen

    2016-10-21

    Electronic cigarettes (e-cigarettes) are heavily marketed and widely perceived as helpful for quitting or reducing smoking intensity. We test whether ever-use of e-cigarettes among early adopters was associated with: 1) increased cigarette smoking cessation; and 2) reduced cigarette consumption. A representative cohort of U.S. smokers (N = 2454) from the 2010 Tobacco Use Supplement to the Current Population Survey (TUS-CPS) was re-interviewed 1 year later. Outcomes were smoking cessation for 30+ days and change in cigarette consumption at follow-up. E-cigarettes use was categorized as for cessation purposes or for another reason. Multivariate regression was used to adjust for demographics and baseline cigarette dependence level. In 2011, an estimated 12 % of adult U.S. smokers had ever used e-cigarettes, and 41 % of these reported use to help quit smoking. Smokers who had used e-cigarettes for cessation were less likely to be quit for 30+ days at follow-up, compared to never-users who tried to quit (11.1 % vs 21.6 %; ORadj = 0.44, 95 % CI = 0.2-0.8). Among heavier smokers at baseline (15+ cigarettes per day (CPD)), ever-use of e-cigarettes was not associated with change in smoking consumption. Lighter smokers (<15 CPD) who had ever used e-cigarettes for quitting had stable consumption, while increased consumption was observed among all other lighter smokers, although this difference was not statistically significant. Among early adopters, ever-use of first generation e-cigarettes to aid quitting cigarette smoking was not associated with improved cessation or with reduced consumption, even among heavier smokers.

  13. Phase variable expression of a single phage receptor in Campylobacter jejuni NCTC12662 influences sensitivity toward several diverse CPS-dependent phages

    DEFF Research Database (Denmark)

    Gencay, Yilmaz Emre; Sørensen, Martine C.H.; Wenzel, Cory Q.

    2018-01-01

    Campylobacter jejuni NCTC12662 is sensitive to infection by many Campylobacter bacteriophages. Here we used this strain to investigate the molecular mechanism behind phage resistance development when exposed to a single phage and demonstrate how phase variable expression of one surface component...... influences phage sensitivity against many diverse C. jejuni phages. When C. jejuni NCTC12662 was exposed to phage F207 overnight, 25% of the bacterial cells were able to grow on a lawn of phage F207, suggesting that resistance develops at a high frequency. One resistant variant, 12662R, was further...... characterized and shown to be an adsorption mutant. Plaque assays using our large phage collection showed that seven out of 36 diverse capsular polysaccharide (CPS)-dependent phages could not infect 12662R, whereas the remaining phages formed plaques on 12662R with reduced efficiencies. Analysis of the CPS...

  14. Activities of daily living (ADL) of single elderly individuals using social assistive programs in a rural community.

    Science.gov (United States)

    Yokokawa, Yoshiharu; Miyoshi, Kei; Kai, Ichiro

    2017-01-01

    Objectives The proportion of elderly individuals living alone is increasing in Japan. Matsumoto city office provides social assistive programs such as home help, lunch delivery, life advice, and safety check telephone calls. The purpose of this study was to compare the level of ADL between the elderly using social assistive programs (the use group) and those who did not (the non-use group).Methods We conducted a cross-sectional study at Shiga district of Matsumoto city in September 2014. A total of 128 elderly individuals participated in this study. Health volunteers asked these subjects to complete a questionnaire without assistance. Measurement items included lifestyle variables and social support networks. With respect to the frequency of use, we used questions that inquired about the use of the social assistive program. We included a set of instruments commonly used in the health assessment of elderly populations: functional capacity (Instrumental ADL, Intellectual Activity, Social Role), social support, nutrition (Mini Nutrition Assessment [MNA]) and depressive symptoms (Geriatric Depression Scale [GDS]).Results The use group consisted of 24 elderly individuals participating in the social support program. The non-use group consisted of 89 elderly individuals living alone without programs. The mean age of those who completed the survey was 83.9±4.2 years for the use group and 82.3±4.3 years for the non-use group. Comparisons between the two groups did not show significant difference in terms of their intellectual activity, social role, emotional social support, and MNA or GDS scores. The use group was more likely to use the public transfer service and receive instrumental social support from children and relatives.Conclusions By means of utilizing the public transfer service, and receiving family support, the elderly living alone who used social assistive programs could live independently. These findings suggest a need for improvement in the public

  15. Risk Factors for Nursing Home Placement in Alzheimer's Disease: A Longitudinal Study of Cognition, ADL, Service Utilization, and Cholinesterase Inhibitor Treatment

    Science.gov (United States)

    Wattmo, Carina; Wallin, Asa K.; Londos, Elisabet; Minthon, Lennart

    2011-01-01

    Purpose of the Study: To identify risk factors for early nursing home placement (NHP) in Alzheimer's disease (AD), focusing on the impact of longitudinal change in cognition, activities of daily living (ADL), service utilization, and cholinesterase inhibitor treatment (ChEI). Design and Methods: In an open, 3-year, prospective, multicenter study…

  16. Unravelling the potential mechanisms behind hospitalization-associated disability in older patients : the hospital-associated disability and impact on daily Life (Hospital-ADL) cohort study protocol

    NARCIS (Netherlands)

    Reichardt, Lucienne A.; Aarden, Jesse J.; van Seben, Rosanne; van der Schaaf, Marike; Engelbert, Raoul H.H.; Bosch, Jos A.; Buurman, Bianca M.

    2016-01-01

    BACKGROUND: Over 30 % of older patients experience hospitalization-associated disability (HAD) (i.e., loss of independence in Activities of Daily Living (ADLs)) after an acute hospitalization. Despite its high prevalence, the mechanisms that underlie HAD remain elusive. This paper describes the

  17. Unravelling the potential mechanisms behind hospitalization-associated disability in older patients : The Hospital-Associated Disability and impact on daily Life (Hospital-ADL) cohort study protocol

    NARCIS (Netherlands)

    Reichardt, L.A.; Aarden, J.J.; van Seben, R.; van der Schaaf, M.; Engelbert, R.H.H.; Bosch, J.A.; Buurman, B.M.

    2016-01-01

    BACKGROUND: Over 30 % of older patients experience hospitalization-associated disability (HAD) (i.e., loss of independence in Activities of Daily Living (ADLs)) after an acute hospitalization. Despite its high prevalence, the mechanisms that underlie HAD remain elusive. This paper describes the

  18. [Factors associated with activities of daily living (ADL) in independently living elderly persons in a community: a baseline examination of a large scale cohort study, Fujiwara-kyo study].

    Science.gov (United States)

    Komatsu, Masayo; Nezu, Satoko; Tomioka, Kimiko; Hazaki, Kan; Harano, Akihiro; Morikawa, Masayuki; Takagi, Masahiro; Yamada, Masahiro; Matsumoto, Yoshitaka; Iwamoto, Junko; Ishizuka, Rika; Saeki, Keigo; Okamoto, Nozomi; Kurumatani, Norio

    2013-01-01

    To investigate factors associated with activities of daily living in independently living elderly persons in a community. The potential subjects were 4,472 individuals aged 65 years and older who voluntarily participated in a large cohort study, the Fujiwara-kyo study. We used self-administered questionnaires consisting of an activities of daily living (ADL) questionnaire with the Physical Fitness Test established by the Ministry of Education, Culture, Sports, Science and Technology (12 ADL items) to determine the index of higher-level physical independence, demographics, Geriatric Depression Scale, and so on. Mini-mental state examination, measurement of physical fitness, and blood tests were also carried out. A lower ADL level was defined as having a total score of the 12 ADL items (range, 12-36 points) that was below the first quartile of a total score for all the subjects. Factors associated with a low ADL level were examined by multiple logistic regression. A total of 4,198 remained as subjects for analysis. The male, female and 5-year-old groups showed significant differences in the median score of 12 ADL items between any two groups. The highest odds ratio among factors associated with lower ADL level by multiple logistic regression with mutually adjusted independent variables was 4.49 (95%CI: 2.82-7.17) in the groups of "very sharp pain" or "strong pain" during the last month. Low physical ability, self-awareness of limb weakness, a BMI of over 25, low physical activity, cerebrovascular disorder, depression, low cognitive function, unable "to see normally", unable "to hear someone", "muscle, bone and joint pain" were independently associated with lower ADL level. Multiple factors are associated with lower ADL level assessed on the basis of the 12 ADL items.

  19. Model-based Development of Safety-critical Functions and ISO 26262 Work Products using modified EAST-ADL

    Directory of Open Access Journals (Sweden)

    Bülent Sari

    2017-07-01

    Full Text Available Safety is becoming more and more important with the ever increasing level of safety related E/E Systems built into the cars. Increasing functionality of vehicle systems through electrification of power train, in future even more by autonomous driving, leads to complexity in designing system, software and safety architecture. ISO 26262 aims to reduce the complexity and to approve the traceability of the different safety activities. This paper presents an approach about model-based development of system, software and safety architecture using Electronics Architecture and Software Technology – Architecture Description Language (EAST-ADL, being in line with the relevant standard ISO 26262. In particular, we briefly discuss how the main safety related activities, such as hazard analysis and risk assessment, developing functional and technical safety concepts and performing safety analysis can be performed model-based and how the activities can be related with system and software development. The state-of-art is also provided and compared with the proposed approach.

  20. AeroADL: applying the integration of the Suomi-NPP science algorithms with the Algorithm Development Library to the calibration and validation task

    Science.gov (United States)

    Houchin, J. S.

    2014-09-01

    A common problem for the off-line validation of the calibration algorithms and algorithm coefficients is being able to run science data through the exact same software used for on-line calibration of that data. The Joint Polar Satellite System (JPSS) program solved part of this problem by making the Algorithm Development Library (ADL) available, which allows the operational algorithm code to be compiled and run on a desktop Linux workstation using flat file input and output. However, this solved only part of the problem, as the toolkit and methods to initiate the processing of data through the algorithms were geared specifically toward the algorithm developer, not the calibration analyst. In algorithm development mode, a limited number of sets of test data are staged for the algorithm once, and then run through the algorithm over and over as the software is developed and debugged. In calibration analyst mode, we are continually running new data sets through the algorithm, which requires significant effort to stage each of those data sets for the algorithm without additional tools. AeroADL solves this second problem by providing a set of scripts that wrap the ADL tools, providing both efficient means to stage and process an input data set, to override static calibration coefficient look-up-tables (LUT) with experimental versions of those tables, and to manage a library containing multiple versions of each of the static LUT files in such a way that the correct set of LUTs required for each algorithm are automatically provided to the algorithm without analyst effort. Using AeroADL, The Aerospace Corporation's analyst team has demonstrated the ability to quickly and efficiently perform analysis tasks for both the VIIRS and OMPS sensors with minimal training on the software tools.

  1. Are there cross-cultural differences of ADL ability in children measured with the Assessment of Motor and Process Skills (AMPS)?

    Science.gov (United States)

    Peny-Dahlstrand, Marie; Gosman-Hedström, Gunilla; Krumlinde-Sundholm, Lena

    2012-01-01

    In many studies of self-care assessments for children, cultural differences in age-norm values have been shown. No study has evaluated whether there are cross-cultural differences in ADL motor and/or process skills in children when measured with the Assessment of Motor and Process Skills (AMPS). To investigate if there were systematic differences in ADL ability measured with the AMPS between children from the Nordic countries and North America and to evaluate the applicability of the existing international age-normative values for children from these two regions. Values from a total of 4 613 children, 3-15 years old, without known disabilities, from these geographical regions were compared with ANOVA. The difference in logits between each region and the mean values for each age group were calculated. No differences of relevance in age-related ADL ability measures between children from the two geographical regions were found, and the age-norm values are applicable to both regions. The AMPS may be considered free from cultural bias and useful in both clinical practice and research concerned with children in both the Nordic countries and North America.

  2. Japan Meteorological Agency/Meteorological Research Institute-Coupled Prediction System version 2 (JMA/MRI-CPS2): atmosphere-land-ocean-sea ice coupled prediction system for operational seasonal forecasting

    Science.gov (United States)

    Takaya, Yuhei; Hirahara, Shoji; Yasuda, Tamaki; Matsueda, Satoko; Toyoda, Takahiro; Fujii, Yosuke; Sugimoto, Hiroyuki; Matsukawa, Chihiro; Ishikawa, Ichiro; Mori, Hirotoshi; Nagasawa, Ryoji; Kubo, Yutaro; Adachi, Noriyuki; Yamanaka, Goro; Kuragano, Tsurane; Shimpo, Akihiko; Maeda, Shuhei; Ose, Tomoaki

    2018-02-01

    This paper describes the Japan Meteorological Agency/Meteorological Research Institute-Coupled Prediction System version 2 (JMA/MRI-CPS2), which was put into operation in June 2015 for the purpose of performing seasonal predictions. JMA/MRI-CPS2 has various upgrades from its predecessor, JMA/MRI-CPS1, including improved resolution and physics in its atmospheric and oceanic components, introduction of an interactive sea-ice model and realistic initialization of its land component. Verification of extensive re-forecasts covering a 30-year period (1981-2010) demonstrates that JMA/MRI-CPS2 possesses improved seasonal predictive skills for both atmospheric and oceanic interannual variability as well as key coupled variability such as the El Niño-Southern Oscillation (ENSO). For ENSO prediction, the new system better represents the forecast uncertainty and transition/duration of ENSO phases. Our analysis suggests that the enhanced predictive skills are attributable to incremental improvements resulting from all of the changes, as is apparent in the beneficial effects of sea-ice coupling and land initialization on 2-m temperature predictions. JMA/MRI-CPS2 is capable of reasonably representing the seasonal cycle and secular trends of sea ice. The sea-ice coupling remarkably enhances the predictive capability for the Arctic 2-m temperature, indicating the importance of this factor, particularly for seasonal predictions in the Arctic region.

  3. Effect of exercise on apparent total tract digestibility of nutrients and faecal recovery of ADL and TiO2 in ponies.

    Science.gov (United States)

    Schaafstra, F J W C; van Doorn, D A; Schonewille, J T; Roelfsema, E; Westermann, C M; Dansen, O; Jacobs, M; Lee, J-Y; Spronck, E A; Blok, M C; Hendriks, W H

    2018-03-07

    Exercise and physical training are known to affect gastrointestinal function and digestibility in horses and can lead to inaccurate estimates of nutrient and energy digestibility when markers are used. The effect of exercise on apparent nutrient digestibility and faecal recoveries of ADL and TiO2 was studied in six Welsh pony geldings subjected to either a low- (LI) or high-intensity (HI) exercise regime according to a cross-over design. Ponies performing LI exercise were walked once per day for 45 min in a horse walker (5 km/h) for 47 consecutive days. Ponies submitted to HI exercise were gradually trained for the same 47 days according a standardized protocol. Throughout the experiment, the ponies received a fixed level of feed and the daily rations consisted of 4.7 kg DM of grass hay and 0.95 kg DM of concentrate. The diet was supplemented with minerals, vitamins and TiO2 (3.0 g Ti/day). Total tract digestibility of DM, organic matter (OM), CP, crude fat, NDF, ADF, starch, sugar and energy was determined with the total faeces collection (TFC) method. In addition, DM and OM digestibility was estimated using internal ADL and the externally supplemented Ti as markers. Urine was collected on the final 2 days of each experimental period. Exercise did not affect apparent digestibility of CP, crude fat, starch and sugar. Digestibility of DM (DMD), OM (OMD), ADF and NDF tended to be lower and DE was decreased when ponies received the HI exercise regime. For all treatments combined, mean faecal recoveries of ADL and Ti were 87.8±1.7% and 99.3±1.7%, respectively. Ti was not detected in the urine, indicating that intestinal integrity was maintained with exercise. Dry matter digestibility estimated with the TFC, ADL and Ti for ponies subjected to LI exercise were 66.3%, 60.3% and 64.8%, respectively, while DMD for HI ponies were 64.2%, 60.3% and 65.2%, respectively. In conclusion, physical exercise has an influence on the GE digestibility of the feed in ponies provided

  4. Quantifying kinematics of purposeful movements to real, imagined, or absent functional objects: implications for modelling trajectories for robot-assisted ADL tasks.

    Science.gov (United States)

    Wisneski, Kimberly J; Johnson, Michelle J

    2007-03-23

    Robotic therapy is at the forefront of stroke rehabilitation. The Activities of Daily Living Exercise Robot (ADLER) was developed to improve carryover of gains after training by combining the benefits of Activities of Daily Living (ADL) training (motivation and functional task practice with real objects), with the benefits of robot mediated therapy (repeatability and reliability). In combining these two therapy techniques, we seek to develop a new model for trajectory generation that will support functional movements to real objects during robot training. We studied natural movements to real objects and report on how initial reaching movements are affected by real objects and how these movements deviate from the straight line paths predicted by the minimum jerk model, typically used to generate trajectories in robot training environments. We highlight key issues that to be considered in modelling natural trajectories. Movement data was collected as eight normal subjects completed ADLs such as drinking and eating. Three conditions were considered: object absent, imagined, and present. This data was compared to predicted trajectories generated from implementing the minimum jerk model. The deviations in both the plane of the table (XY) and the sagittal plane of torso (XZ) were examined for both reaches to a cup and to a spoon. Velocity profiles and curvature were also quantified for all trajectories. We hypothesized that movements performed with functional task constraints and objects would deviate from the minimum jerk trajectory model more than those performed under imaginary or object absent conditions. Trajectory deviations from the predicted minimum jerk model for these reaches were shown to depend on three variables: object presence, object orientation, and plane of movement. When subjects completed the cup reach their movements were more curved than for the spoon reach. The object present condition for the cup reach showed more curvature than in the object

  5. Quantifying kinematics of purposeful movements to real, imagined, or absent functional objects: Implications for modelling trajectories for robot-assisted ADL tasks**

    Directory of Open Access Journals (Sweden)

    Wisneski Kimberly J

    2007-03-01

    Full Text Available Abstract Background Robotic therapy is at the forefront of stroke rehabilitation. The Activities of Daily Living Exercise Robot (ADLER was developed to improve carryover of gains after training by combining the benefits of Activities of Daily Living (ADL training (motivation and functional task practice with real objects, with the benefits of robot mediated therapy (repeatability and reliability. In combining these two therapy techniques, we seek to develop a new model for trajectory generation that will support functional movements to real objects during robot training. We studied natural movements to real objects and report on how initial reaching movements are affected by real objects and how these movements deviate from the straight line paths predicted by the minimum jerk model, typically used to generate trajectories in robot training environments. We highlight key issues that to be considered in modelling natural trajectories. Methods Movement data was collected as eight normal subjects completed ADLs such as drinking and eating. Three conditions were considered: object absent, imagined, and present. This data was compared to predicted trajectories generated from implementing the minimum jerk model. The deviations in both the plane of the table (XY and the saggital plane of torso (XZ were examined for both reaches to a cup and to a spoon. Velocity profiles and curvature were also quantified for all trajectories. Results We hypothesized that movements performed with functional task constraints and objects would deviate from the minimum jerk trajectory model more than those performed under imaginary or object absent conditions. Trajectory deviations from the predicted minimum jerk model for these reaches were shown to depend on three variables: object presence, object orientation, and plane of movement. When subjects completed the cup reach their movements were more curved than for the spoon reach. The object present condition for the cup

  6. Functional competency and cognitive ability in mild Alzheimer's disease: relationship between ADL assessed by a relative/ carer-rated scale and neuropsychological performance.

    Science.gov (United States)

    Matsuda, Osamu; Saito, Masahiko

    2005-06-01

    Alzheimer's disease (AD) is characterized by multiple cognitive deficits and affects functional competency to perform daily activities (ADL). As this may contribute to the patient's overall disability, it is important to identify factors that compromise competency. The relationship between different cognitive domains and functional activities in AD was studied. The functional competency of 73 Japanese AD patients, most with mild dementia, was assessed using a 27-item relative/carer-rating scale covering 7 ADL: managing finances, using transportation, taking precautions, self-care, housekeeping, communication and taking medicine. Cognitive assessment used 16 neuropsychological tests from the Japanese version of the WAIS-R and COGNISTAT, covering 9 cognitive domains: orientation, attention, episodic memory, semantic memory, language, visuoperceptual and construction abilities, computational ability, abstract thinking, and psychomotor speed. Multiple regression analysis by the stepwise method indicated that functional competency could, for the most part, be predicted from test scores for orientation, abstract thinking and psychomotor speed. The results of this study suggest that impairment of these three cognitive domains plays an important role in the functional deterioration of AD.

  7. Function generation and regulation libraries and their application to the control of the new main power converter (POPS) at the CERN CPS

    International Nuclear Information System (INIS)

    King, Q.; Page, S.T.; Thiesen, H.; Veenstra, M.

    2012-01-01

    Power converter control for the LHC is based on an embedded control computer called a Function Generator/Controller (FGC). Every converter includes an FGC with responsibility for the generation of the reference current as a function of time and the regulation of the circuit current, as well as control of the converter state. With many new converter controls software classes in development it was decided to generalize several key components of the FGC software in the form of C libraries: function generation in libfg, regulation, limits and simulation in libreg and DCCT, ADC and DAC calibration in libcal. These libraries were first used in the software class dedicated to controlling the new 60 MW main power converter (POPS) at the CERN Proton Synchrotron (CPS) where regulation of both magnetic field and circuit current is supported. This paper reports on the functionality provided by each library and in particular libfg and libreg. The libraries are already being used by software classes in development for the next generation FGC for Linac4 converters, as well as the CERN SPS converter controls (MUGEF) and MedAustron converter regulation board. (authors)

  8. Adrienne Rich'in "Diving into the Wreck" Adlı Şiirine Eko Feminist Bir Yaklaşım

    OpenAIRE

    ERKAN, Ayça Ülker

    2014-01-01

    Bu çalışmada Adrienne Rich\\'in şiirlerinden olan “Diving into the Wreck” (1973) adlı şiiri eko feminist eleştiri bağlamında incelenmektedir. Rich\\'in doğa şiirleri, kadın tarafsızlığını ve bilincini, ata erkil suistimalini ve önem vermeme varsayımlarını sorgular. Şiirdeki androjen (çift cinsiyetli) karakter “ben” ile birlikte Rich, dişi öznelliğine yer verebilmek için toplumsal cinsiyet ve cinsiyet sınırlarının ötesine gider. Şiirdeki karakter dişi kimliğini ve cinselliğini mecazi b...

  9. Tradução, validação e adaptação cultural da escala de atividade de vida diária Translation, validation and cultural adaptation of the 'activities of daily living' scale (ADLS

    Directory of Open Access Journals (Sweden)

    Priscila Zeitune Nigri

    2007-01-01

    Full Text Available OBJETIVO: Realizar a tradução, adaptação cultural e validação do "Knee Outcome Survey- Activities of Daily Living Scale" (ADLS para a língua portuguesa, bem como verificar suas propriedades de medida, reprodutibilidade e validade, para que o mesmo possa ser usado como um instrumento específico para avaliação de sintomas em pacientes brasileiros portadores de afecções no joelho durante as atividades de vida diária. MÉTODOS: Foram realizadas 2 entrevistas,na primeira o questionário foi aplicado em conjunto ao Lysholm, SF-36 e EAV (examinador 1. Após aproximadamente 30 minutos da primeira entrevista, os mesmos pacientes responderam apenas ao ADLS (examinador 2. Após um intervalo entre 7 a 10 dias, foi realizada a terceira entrevista constituída de nova aplicação do ADLS (examinador 2. RESULTADOS: A amostra consistiu de 53 entrevistados, sendo a média de idade de 33.0566 anos e patologia mais freqüente a lesão ligamentar (56,6%. O índice de Sperman obteve um valor de 0,986 (alfa=0,05, roOBJECTIVES: To perform the translation, cultural adaptation and validation of the "Knee Outcome Survey - Activities of Daily Living Scale" (ADLS into Portuguese, as well as to check its measurement, reproducibility and validity properties in order to make it useful as a specific instrument for evaluating symptoms in Brazilian patients with knee injuries during their daily living activities. METHODS: Two interviews were performed; in the first interview, the questionnaire was applied along with Lysholm's, SF-36 and VAS (investigator 1. Approximately 30 minutes after the first interview, the same patients answered only the ADLS (investigator 2. After a break of 7 to 10 days, a third additional interview with the ADLS was applied (investigator 2. RESULTS: The sample was constituted of 53 subjects, with mean age of 33.0566 years, with the most frequent pathology being ligamentar injury (56.6%. The Spearman's index used for inter

  10. The Glittre-ADL test reflects functional performance measured by physical activities of daily living in patients with chronic obstructive pulmonary disease

    Directory of Open Access Journals (Sweden)

    Manuela Karloh

    2016-01-01

    Full Text Available ABSTRACT Background The Glittre-ADL test (TGlittre is a valid and reliable test for the evaluation of functional capacity and involves multiple physical activities of daily living (PADL, which are known to be troublesome to patients with Chronic Obstructive Pulmonary Disease (COPD. However, it is still unknown if this test is also able to reflect the functional performance of patients with COPD. Objective To investigate whether the TGlittre reflects the functional performance of COPD patients and whether the necessary time to complete the TGlittre and the PADL varies according to disease severity. Method Thirty-eight patients with COPD (age 65, SD=7 years; forced expiratory volume in the first second 41.3, SD=15.2% predicted underwent anthropometric and lung function assessments and were submitted to the TGlittre and PADL measurement. Results TGlittre performance correlated significantly (p<0.05 with PADL variables, such as time sitting (r=0.50, walking (r=-0.46, number of steps taken (r=–0.53, walking movement intensity (r=–0.66, walking energy expenditure (r=-0.50, and total energy expenditure (r=–0.33. TGlittre performance was not significantly different in patients among the Global Initiative for COPD (GOLD spirometric stages, but walking and sitting time were significantly lower and greater, respectively, in severe and very severe patients compared to those with moderate disease (p<0.05. Conclusion The performance on the TGlittre correlates with walking and sitting time and other real life PADL measurements. The severity of the disease is associated with the differences in the level of physical activity in daily life more than in functional capacity.

  11. Two novel Pb(II) coordination polymers (CPs) based on 4-(4-oxopyridin-1(4H)-yl) and 3-(4-oxopyridin-1(4H)-yl) phthalic acid: Band gaps, structures, and their photoelectrocatalytic properties in CO2-saturated system

    Science.gov (United States)

    Yan, Zhi Shuo; Long, Ji Ying; Gong, Yun; Lin, Jian Hua

    2018-05-01

    Based on 4-(4-oxopyridin-1(4H)-yl) phthalic acid (H2L1) and 3-(4-oxopyridin-1(4H)-yl) phthalic acid (H2L2), two novel Pb(II) coordination polymers (CPs) formulated as [Pb4Cl4·(L1)2·H2O]n (CP 1), [Pb3Cl4·L2·H2O]n (CP 2) were solvothermally synthesized and characterized by single-crystal X-ray diffraction. The two novel Pb(II) CPs (CPs 1 and 2) possessed different structures. Density functional theory (DFT) calculations revealed the two CPs had different band structures yet the characteristic of semiconductors in common. Their valence band (VB) and conduction band (CB) positions were determined by Mott-Schottky and UV-visible diffuse reflectance analyses. The photoelectrocatalytic performance of the two CPs towards CO2 reduction were tested by photocurrent responses at various applied potentials. And the E =-1.4 V vs SCE (-0.74 V vs NHE) was selected as the required potential according to the regulation of photocurrent responses at various tested potentials in CO2-saturated system. The photoelectrocatalytic performance of CP 2 was superior to that of CP 1 owing to the well-matched CB position of CP 2 and CO2 reduction potentials at the required potential of -1.4 V vs SCE (-0.74 V vs NHE). In addition, the photoelectrolytic experiment were performed 1 h in the CO2-saturated 0.2 M Na2SO4 solution at the required potential of -1.4 V vs SCE (-0.74 V vs NHE) with and without illumination, and we initially demonstrated the influence of visible light in the CO2-saturated photoelectrocatalytic measurement system and the reason of stability in 1 h chronoamperometry.

  12. Hasan Basri Çantay’ın “On Kere Kırk Hadis” Adlı Eserinde Ahkâm Hadislerine Getirdiği Fıkhî Yorumlar

    Directory of Open Access Journals (Sweden)

    Mehmet Özkan

    2015-06-01

    Full Text Available Milli mücadele yıllarının öne çıkan isimlerinden biri olan Hasan Basri Çantay yazarlık, gazetecilik, öğretmenlik ve milletvekilliği gibi birçok alanda faaliyet göstermiş, çeşitli konularda yazılar yazmış, eserler kaleme almıştır. İslami ilimler alanında da kendini yetiştiren Çantay’ın bu alandaki en önemli eseri “Kur’an-ı Hakîm ve Meal-i Kerîm” adlı Kur’an mealidir. İkinci önemli eseri, “On Kere Kırk Hadis” adlı kitabıdır. 1955-1962 yılları arasında üç cilt halinde basılan bu kitap iman, ibâdet, temizlik, ahlak, muâmelat, evlenme, boşanma, suç ve cezalar, şûra, askerlik ve cihat, savaş hukuku,  helal,  haram gibi birçok konuyla ilgili bin iki yüz hadisten oluşmaktadır. Bunların yaklaşık dört yüz yirmisi ahkâm hadisidir. Çantay, hadisleri tercüme etmekle kalmamış yeri geldikçe izahlarda da bulunmuştur. Bu çalışmada Çantay’ın yaklaşık yüz otuz ahkâm hadisine yaptığı izah ve fıkhî değerlendirmelerden örneklere yer verilecektir.

  13. Test Case RCM-3 Using CPS

    Science.gov (United States)

    2001-03-01

    influence We observe an important variation of the flame length with the ratio gas / liquid injected (Figure 6 and Figure 7). The flame length increases with...fraction, the flame length increases (Figure 7). This is due to the increase of the oxygen injection speed to obtain the correct amount of oxygen...influence of C, with have made calculation with an arbitrary value for a witch is 10-6 N / m. The flame length decrease with the surface tension

  14. Deficiency of RgpG Causes Major Defects in Cell Division and Biofilm Formation, and Deficiency of LytR-CpsA-Psr Family Proteins Leads to Accumulation of Cell Wall Antigens in Culture Medium by Streptococcus mutans.

    Science.gov (United States)

    De, Arpan; Liao, Sumei; Bitoun, Jacob P; Roth, Randy; Beatty, Wandy L; Wu, Hui; Wen, Zezhang T

    2017-09-01

    Streptococcus mutans is known to possess rhamnose-glucose polysaccharide (RGP), a major cell wall antigen. S. mutans strains deficient in rgpG , encoding the first enzyme of the RGP biosynthesis pathway, were constructed by allelic exchange. The rgpG deficiency had no effect on growth rate but caused major defects in cell division and altered cell morphology. Unlike the coccoid wild type, the rgpG mutant existed primarily in chains of swollen, "squarish" dividing cells. Deficiency of rgpG also causes significant reduction in biofilm formation ( P cell envelope biogenesis, were constructed using the rgpG mutant. There were no major differences in growth rates between the wild-type strain and the rgpG brpA and rgpG psr double mutants, but the growth rate of the rgpG brpA psr triple mutant was reduced drastically ( P cells with multiple asymmetric septa. When analyzed by immunoblotting, the rgpG mutant displayed major reductions in cell wall antigens compared to the wild type, while little or no signal was detected with the double and triple mutants and the brpA and psr single mutants. These results suggest that RgpG in S. mutans plays a critical role in cell division and biofilm formation and that BrpA and Psr may be responsible for attachment of cell wall antigens to the cell envelope. IMPORTANCE Streptococcus mutans , a major etiological agent of human dental caries, produces rhamnose-glucose polysaccharide (RGP) as the major cell wall antigen. This study provides direct evidence that deficiency of RgpG, the first enzyme of the RGP biosynthesis pathway, caused major defects in cell division and morphology and reduced biofilm formation by S. mutans , indicative of a significant role of RGP in cell division and biofilm formation in S. mutans These results are novel not only in S. mutans , but also other streptococci that produce RGP. This study also shows that the LytR-CpsA-Psr family proteins BrpA and Psr in S. mutans are involved in attachment of RGP and probably

  15. Faruk Nafiz Çamlıbel’in Suda Halkalar Adlı Eserinde Su İmajları ve Benzetmeler Water Images and Metaphors in Suda Halkalar Which Faruk Nafiz Çamlıbel’s Work

    Directory of Open Access Journals (Sweden)

    Hüseyin DOĞRAMACIOĞLU

    2012-09-01

    Full Text Available Suda Halkalar (Circles in Water which the poetry book of Faruk Nafiz Çamlıbel, has not been translated into the Latin alphabet to the present day. The images of the water and metaphors which used in this work brought new connotations and approaches to the Turkish poetry. The images of the water in the poetry book are used instead of the poet's soul and dreams sometimes. These images are thought with poet’s darling and sometimes are used as a background. The poetformed the images of the water in his poem sadly. There are the poetand his darling in these tables. The images of the water and thedreams of the poet form the background of the poem. The backgroundsin this poem are repeated as a leitmotiv. Visuality and individualitybecomes important feature in these tables created by the poet. Themetaphors in the work created differently from classical Turkish poetry.These metaphors brought a new meaning to the poem. The poem basedon the intellectual grounds via metaphors. This can be considered asone of the significant achievements of Turkish poetry. We can see thatthe past remembered and desired both in poetry and metaphors bypessimistic feeling. In this respect the past affects the poet's dreamscombining with a sense of mourning, water images and metaphors inpoetry. The metaphors can be grouped as imaginary, visual andstrongly poetic ground. The feelings of pessimism and sadness arepredominant in these metaphors. The images and metaphors used bythe poet can be considered as an improvement for Turkish poetry. It isthe first research done on Suda Halkalar (Circles in Water will help tobetter understand and identify Çamlıbel’s aspect of poetry and literaryline. Faruk Nafiz Çamlıbel’in Suda Halkalar adlı şiir kitabı günümüze kadar Latin harflerine aktarılmamıştır. Bu eserde kullanılan su imajları ve benzetmeler Türk şiirine yeni yaklaşımlar ve çağrışımlar getirmiştir. Eserdeki su imajları bazen şairin ruhu ve hayalleri

  16. Halveti-Şâbânî Şeyhi Mustafa Kemâleddîn Bekrî ve Hediyyetü’l-Ahbâb Adlı Eseri

    Directory of Open Access Journals (Sweden)

    Halim Gül

    2013-03-01

    Full Text Available AbstractThis article studies the life and woks of Kemaleddin Bekrî, who affiliated himself to Khalvati-Shabani Sheikh Abdullatîf b. Hüsameddîn el-Halebî, and who was growed up under Abd al-Ghani al-Nabulsi’s control. His work “Hadiyyat al-Ahbab fi ma li’l-Khalveti min al-Şuruti va’l-Adab”, which explains the conditions and rules of “khalvet” was also studied. The work consists of preface, eight parts and an epilogue and all parts examined in detail.ÖzetBu makalede, Abdülganî Nablusî’nin (ö.1143/1730 gözetiminde yetişen, halvetî-Şabânî şeyhi Abdullatîf b. Hüsameddîn el-Halebî’ye intisap eden Mustafa Kemaleddin Bekrî’nin hayatı ve eserleri incelenmiştir. Bu çerçevede onun tasavvufi bir kavram olan halvetin âdab ve şartlarını izah eden “Hediyyetü’l ahbâb fî mâ li’l-halveti mine’ş-şurûti ve’l-âdâb” adlı risalesinin incelenmesi ve değerlendirmesi üzerinde durulmuştur. Söz konusu eser, mukaddime sekiz bölüm ve bir hatimeden oluşmaktadır.Le Shaykh Khalwatî-Sha‘bânî Mustafâ Kamâl al-Dîn Bakrî et son Traité qui s’intitule Hadiyya al-ahbâbRésuméDans cet article, on va étudier d’abord la vie et les œuvres du Shaykh Khalwatî-Sha‘bânî Mustafâ Kamâl al-Dîn Bakrî qui a été éduqué par le célèbre soufi ‘Abd al-Ghanî Nablûsî (m. 1143/1730 et a été initié par ‘Abd al-Latîf b. Husâm al-Dîn al-Halabî. Puis, plus particulièrement, on va analyser son traité qui s’intitule ‘Hadiyya al-ahbâb fî mâ li’l-khalwatî min al-shurût wa’l-âdâb’. Ce traité – qui a été composé de dix-huit chapitres et d’une conclusion – étudie les convenances et les conditions de la retraite spirituelle, khalwa, une des notions soufies importantes

  17. Mehmed Enisî Yalkı’nın Alman Ruhu Adlı Seyahatnamesine İmgebilimsel Bir Yaklaşım An Imagologist Approach To Mehmet Enisi Yalkı's Travelbook

    Directory of Open Access Journals (Sweden)

    Yılmaz DAŞCIOĞLU

    2012-12-01

    , Cumhuriyetle birlikte sistematik hale getirilen batı tipi Türk kimliğinin inşasında önemli bir görev üstlendiğini söylemek yanlış olmayacaktır. Bu çalışmada, II. Meşrutiyet’in ilanı ile birlikte büyük bir artış gösteren yurt dışı seyahatnamelerinden birisi imgebilimsel yöntemle incelenmektedir. Meşrutiyet dönemi isimlerinden gazeteci-yazar Mehmed Enisî Yalkı’nın, henüz Latin alfabesine aktarılmayan Alman Ruhu adlı seyahatnamesinde yeni bir ulusun, batı tipi Türk’ün inşası için teklif ettiği Alman/Almanya modeli çeşitli imgeler aracılığıyla çözümlenmektedir. Bütün bir seyahatname boyunca “Alman gibi çalış”, “Alman gibi metin ol”, “Alman gibi ruhunu kuvvetlendir”, “Alman gibi adalete hizmet et” nidalarının bir arka fon olarak çınlaması, Almanya’nın model alınmasının teklif edilmesinin açık işaretleridir. Çalışmanın sonunda, Tanzimat’tan Cumhuriyet’e kadar uzanan yeni bir ulusun inşası bunalımını yaşayan Osmanlı aydınının, seyahatnameyi bir edebi tür gibi kullanmaktan çok, toplumu eğitmek, ona yön vermek, ona alternatif yaşam ve kültür sunmak kaygısıyla kaleme aldığı tespit edilmektedir.

  18. The CPS improvements 1965-1973 An assessment

    CERN Document Server

    CERN CPS staff

    1974-01-01

    I n 1965 , plan s wer e mad e t o increas e th e bea m intensit y delivere d b y th e CP S b y a facto r o f te n o r more . Th e firs t stage , involvin g a ne w powe r suppl y fo r th e mai n magne t an d mor e tha n doublin g th e cycl e repe titio n rate , wa s complete d i n 1968 . I n th e secon d stage , whic h i s no w essentiall y complete , th e majo r item s wa s th e constructio n o f a n 80 0 Me V slow-cyclin g booste r injector . Man y othe r modification s wer e inclu ded . Th e Lina c curren t ha d t o b e increase d b y a n orde r o f magnitud e t o suppl y th e Booster , an d th e highe r bea m intensitie s require d a mor e powerfu l R F acceleratin g system. Besides the 800 MeV injection elements, quadru-pole lenses were installed to avoid longitudinal dilu­ tio n a t transition , an d multipole s t o counterac t insta bilities . I n addition , th e chambe r vacuu m wa s impro...

  19. Risk Assessment of Power System considering the CPS of Transformers

    Science.gov (United States)

    Zhou, Long; Peng, Zewu; Liu, Xindong; Li, Canbing; Chen, Can

    2018-02-01

    This paper constructs a risk assessment framework of power system for device-level information security, analyzes the typical protection configuration of power transformers, and takes transformer gas protection and differential protection as examples to put forward a method that analyzes the cyber security in electric power system, which targets transformer protection parameters. We estimate the risk of power system accounting for the cyber security of transformer through utilizing Monte Carlo method and two indexes, which are the loss of load probability and the expected demand not supplied. The proposed approach is tested with IEEE 9 bus system and IEEE 118 bus system.

  20. The measurement of instrumental ADL: content validity and construct validity

    DEFF Research Database (Denmark)

    Avlund, K; Schultz-Larsen, K; Kreiner, S

    1993-01-01

    do not depend on help. It is also possible to add the items in a valid way. However, to obtain valid IADL-scales, we omitted items that were highly relevant to especially elderly women, such as house-work items. We conclude that the criteria employed for this IADL-measure are somewhat contradictory....... showed that 14 items could be combined into two qualitatively different additive scales. The IADL-measure complies with demands for content validity, distinguishes between what the elderly actually do, and what they are capable of doing, and is a good discriminator among the group of elderly persons who...

  1. ADL: a graphical design language for real time parallel applications

    NARCIS (Netherlands)

    M.R. van Steen; T. Vogel; A. ten Dam

    1993-01-01

    textabstractDesigning parallel applications is generally experienced as a tedious and difficult task, especially when hard real-time performance requirements have to be met. This paper discusses on-going work concerning the construction of a Design Entry System which supports the design phase of

  2. AMEM-ADL Polymer Migration Estimation Model User's Guide

    Science.gov (United States)

    The user's guide of the Arthur D. Little Polymer Migration Estimation Model (AMEM) provides the information on how the model estimates the fraction of a chemical additive that diffuses through polymeric matrices.

  3. “Gülün Adı ve Benim Adım Kırmızı” Adlı Romanlara Karşılaştırmalı Bir Yaklaşım A Comparative Approach to the novels “Name of the Rose and My Name Is Red”

    Directory of Open Access Journals (Sweden)

    Elmas ŞAHİN

    2013-09-01

    Literature; Concepts of Criticism (1963, C:L: Wrenn'in The Idea of Comparative Literature (1973, Rey Chow'un In the Name of Comparative Literature (1995 gibi eserlerle, bizde ise İnci Enginün'ün Mukayeseli Edebiyat (1992, Gürsel Aytaç'ın Karşılaştırmalı Edebiyat Bilimi (1997, Emel Kefeli'nin Karşılaştırmalı Edebiyat İncelemeleri (2000 ve Kamil Aydın’ın Karşılaştırmalı Edebiyat: Günümüz Postmodern Bağlamda Algılanışı (2008 adlı çalışmalar karşılaştırmalı edebiyat bilimine katkı sağlayan ilk kuramsal yaklaşımlardandır.Karşılaştırmalı edebiyat, 1950’lerden sonra postmodern edebiyatın da gelişmesiyle birlikte metinlerarasılık kavramıyla da adını sıkça duyurmaya başlar. Gerek dil gerekse tema ve teknik açılardan eş ya da art zamanlı benzerlikler; metinlerarası göndermeler, alıntılar, montajlar; benzer söylemler ve kaynak metnin yeniden yorumlanışı gibi etkileşimler karşılaştırmalı edebiyat bilimini yakından ilgilendirir.Bu bağlamda çağımız yazarlarından İtalyan yazarı Umberto Eco'nun Gülün Adı (1980 ile Orhan Pamuk'un Benim Adım Kırmızı (1998 adlı eserleri farklı coğrafyalarda edebiyat sahasına girmelerine karşın, içerik ve biçim bağlamında benzer noktalara sahiptirler vekarşılaştırmalı edebiyat için eş zamanlı bir örnek teşkil etmektedirler.Bu çalışmada Gülün Adı ile Benim Adım Kırmızı adlı eserler, metneodaklı inceleme metodu kullanılarak öz ve biçim açısındankarşılaştırılacaktır. Her iki eser de, ortak tür, konu ve motifler dikkatealınarak; metinlerarası boyutta irdelenip; karşılaştırmalı edebiyatyönetimiyle benzer ve farklılıklarıyla çözümlenecektir.

  4. Measuring change in activities of daily living in nursing home residents with moderate to severe cognitive impairment

    Directory of Open Access Journals (Sweden)

    Fries Brant E

    2006-04-01

    Full Text Available Abstract Background The objective of this study was to assess the responsiveness of the Minimum Data Set Activities of Daily Living (MDS-ADL Scale to change over time by examining the change in physical function in adults with moderate to severe dementia with no comorbid illness who had been resident in a nursing home for over 90 days. Methods Longitudinal data were collected on nursing home residents with moderate (n = 7001 or severe (n = 4616 dementia in one US state from the US national Minimum Data Set (MDS. Severity of dementia was determined by the MDS Cognitive Performance Scale (CPS. Physical function was assessed by summing the seven items (bed mobility, transfer, locomotion, dressing, eating, toilet use, personal hygiene on the MDS activities of daily living (ADL Long Form scale. Mean change over time of MDS-ADL scores were estimated at three and six months for residents with moderate (CPS score of 3 and severe (CPS score of 4 or 5 dementia. Results Physical function in residents with moderate cognitive impairment deteriorated over six months by an average of 1.78 points on the MDS-ADL Long Form scale, while those with severe cognitive impairment declined by an average of 1.70 points. Approximately one quarter of residents in both groups showed some improvement in physical function over the six month period. Residents with moderate cognitive impairment experienced the greatest deterioration in early-loss and mid-loss ADL items (personal hygiene, dressing, toilet use and residents with severe cognitive impairment showed the greatest deterioration in activities related to eating, a late loss ADL. Conclusion The MDS-ADL Long Form scale detected clinically meaningful change in physical function in a large cohort of long-stay nursing home residents with moderate to severe dementia, supporting its use as a research tool in future studies.

  5. Measuring change in activities of daily living in nursing home residents with moderate to severe cognitive impairment

    Science.gov (United States)

    Carpenter, G Iain; Hastie, Charlotte L; Morris, John N; Fries, Brant E; Ankri, Joel

    2006-01-01

    Background The objective of this study was to assess the responsiveness of the Minimum Data Set Activities of Daily Living (MDS-ADL) Scale to change over time by examining the change in physical function in adults with moderate to severe dementia with no comorbid illness who had been resident in a nursing home for over 90 days. Methods Longitudinal data were collected on nursing home residents with moderate (n = 7001) or severe (n = 4616) dementia in one US state from the US national Minimum Data Set (MDS). Severity of dementia was determined by the MDS Cognitive Performance Scale (CPS). Physical function was assessed by summing the seven items (bed mobility, transfer, locomotion, dressing, eating, toilet use, personal hygiene) on the MDS activities of daily living (ADL) Long Form scale. Mean change over time of MDS-ADL scores were estimated at three and six months for residents with moderate (CPS score of 3) and severe (CPS score of 4 or 5) dementia. Results Physical function in residents with moderate cognitive impairment deteriorated over six months by an average of 1.78 points on the MDS-ADL Long Form scale, while those with severe cognitive impairment declined by an average of 1.70 points. Approximately one quarter of residents in both groups showed some improvement in physical function over the six month period. Residents with moderate cognitive impairment experienced the greatest deterioration in early-loss and mid-loss ADL items (personal hygiene, dressing, toilet use) and residents with severe cognitive impairment showed the greatest deterioration in activities related to eating, a late loss ADL. Conclusion The MDS-ADL Long Form scale detected clinically meaningful change in physical function in a large cohort of long-stay nursing home residents with moderate to severe dementia, supporting its use as a research tool in future studies. PMID:16584565

  6. Halit Fahri Ozansoy'un Gülistanlar ve Harabeler Adlı Eserinde Bahçe İmajları ve Renkler Garden Images and Colors in Halit Fahri Ozansoy’s Work of Gülistanlar ve Harabeler

    Directory of Open Access Journals (Sweden)

    Hüseyin DOĞRAMACIOĞLU

    2012-12-01

    Full Text Available Halit Fahri Ozansoy’s poetry books of Gülistanlar ve Harabeler printed with old letters but not transformed to the Latin alphabet until now. In his work, garden images and colors which loaded special meaning of poet was known as hidden pearls and no research have been made on this work till now. Garden images in poetry are sometimes colorful, light and sometimes dull and dark. These images change with the with the poet's spirit world. We can visualize the garden images like an oil painting. These images drawn by the poet's words, show poet’s mood like a mirror. The colors used in the poem vary with garden images. This change appears with the change of the mental status of the poet. Thus, the poet uses the colors in accordancewith the different tables and his mood. When there are a lively andwarm colors in optimistic tables, dark and dull colors chosen inpessimistic tables. The poet's choice of the colors is not a coincidence.This selectivity included to poetry with different sensations. In his work,Ozansoy has described variety of colors in different gardens.Imagination, imagery and various emotions had been made with oneaccord in his depictions. The colors and portraits of garden form thepoet’s imagination. Colorful memories in the garden which experiencedin a darling moves from poet's imagination to the verses of the poem.Imagination, colors and gardens are described with darling. Theseimageries compose the garden images and semantic change of thecolors. Halit Fahri Ozansoy’un Gülistanlar ve Harabeler adlı şiir kitabı eski harflerle basılmış ancak günümüze kadar Latin harflerine aktarılmamıştır. Bu eserde şairin bahçe imajları ve renklere yüklediği anlamlar saklı inciler gibi gizli kalmış ve günümüze kadar üzerinde inceleme yapılmamıştır. Şiirdeki bahçe imajları bazen renkli, ışıklı ve bazen de donuk ve karanlıktır. Şairin değişen ruh dünyası ile birlikte bu imajlar da değişir. Bah

  7. “Beyhude Ömrüm” Adlı Hikâyenin Greımas’ın Eyleyenler Modeline Göre İncelenmesi Analysıs Of Story “Beyhude Ömrüm” Accordıng To Greımas’ Actants Model

    Directory of Open Access Journals (Sweden)

    Hatice ALTUNKAYA

    2012-12-01

    önüştürmek, anlamsal bağlarını keşfetmek okurun işidir. Eski Yunancada gösterge anlamına gelen semeion ile bilim anlamına gelen logos sözcüğünün birleşmesiyle meydana gelen semology Türkçede gösterge bilimi terimiyle karşılanmaktadır.Göstergebilimin öncüleri olarak iki isimden söz etmek mümkündür. Bunlar Charles Sanders Peirce ve İsviçreli dilbilimci Ferdinand de Saussure’dür. Peirce, “Tüm evren, yalnızca göstergelerden oluşmamış olsa bile, göstergelerle dolup taşar” sözü ile bütün bilgi nesnelerinin göstergebilimin konusu olabileceğini ifade etmiştir.Bu çalışmada Mustafa Kutlu’nun “Beyhude Ömrüm” adlı hikâyesi göstergebilimsel bir çözümleme modeli olan Greimas’ın eyleyenler modeline göre incelenmeye çalışılmıştır. A.J. Greimas’a göre anlatının oluşabilmesi için öyküyü başlatacak bir olay ve bu başlangıç durumunu bozacak dönüştürücü ögeye ihtiyaç vardır. Çalışmada söz konusu olay ve dönüştürücü ögenin var olduğundan hareketle hikâye beş kesite ayrılmıştır. Bu kesitlerde eyleyenler modelinde bulunan altı eyleyenin bulunduğu, anlatı izlencesinden eyletim, edinç, edim ve yaptırım izlence evrelerinin yer aldığı tespit edilmiş ve eyleyenler modelindeki öznelerin yetilendirici, sonuçlandırıcı ve onurlandırıcı deneyimleri gerçekleştirdikleri görülmüştür. Ayrıca eserde ben anlatıcı olan yazarın “öldüm” ifadesini kullanmasının ben anlatıcının anlatımına uygun düşen bir anlatım olmadığı görülmüştür.

  8. Tokat’ın 17. Yüzyıl Âlim Şairlerinden İshak Bin Hasan Tokatî ve Nazmu’l-Ulum Adlı Mesnevîsi Poetry in Rhymed Couplets of Tokatlı İshâk Efendi Nazmu'l-Ulûm

    Directory of Open Access Journals (Sweden)

    Bayram ÖZFIRAT

    2013-03-01

    ncelediğimiz Nazmu’l-Ulûm adlı mesnevîsinde şâir, çeşitli ilimler hakkında bilgi verdikten sonra bunların öğrenilmesi gerektiğini vurgulamıştır. Mesnevî, arûz vezninin “Mefāīlün Mefāīlün Faūlün” kalıbıyla yazılmış olup 1098/1687 yılında Tokat’ta telif edilmiştir. Mesnevî toplam 422 beyittir. Araştırmalarımız neticesinde yirmi iki nüshasını tespit ettiğimiz mesnevîde çeşitli ilimler hakkında bilgi verildikten sonra bunların öğrenilmesi gereği vurgulanmaktadır. Nazmu’l-Ulûm bu yönüyle manzûm bir nasihatnâme olup öğrenilmesinin öğütlendiği ilimlerin bazıları şunlardır: 1. İlm-i tecvîd, 2. İlm-i Kelâm, 3. İlm-i Fıkıh, 4. İlm-i Tasavvuf ve Ahlâk, 5. İlm-i Hadîs, 6. İlm-i Tefsîr, 7. İlm-i Tıp, 8. İlm-i Lugat, 9. İlm-i Nahv ve Sarf, 10. İlm-i Mantık, 11. İlm-i Edeb, 12. İlm-i Usûl-i Fıkıh, 13. İlm-i Meânî, 14. İlm-i Hisâb, 15. İlm-i Hendese, 17. İlm-i Kîmyâ, 18. İlm-i Arûz, 19. İlm-i Eş’âr. Nazmu’l-Ulûm kafiye yönünden oldukça sağlamdır. Hatta eserin kafiye bakımından kusursuz bir yapıya sahip olduğunu söylemek de mümkündür. Mesnevîyi oluşturan kelimler dikkate alındığında Arapça ve Farsça kelimelerin çokluğu dikkat çekmektedir. Ama eserin bu özelliği onun akıcılığından bir şey kaybettirmemiştir. Mesnevîde her türlü kafiyeye rastlanmakla birlikte; en çok zengin ve tam kafiyelere yer verilmiş, az sayıda yarım kafiye kullanılmıştır. Mesnevîde, bolca söz sanatlarına ve tasvirlere yer verilmiştir. Gereksiz ifadelerden kaçınılmaya çalışılmıştır. İshâk Efendi arûz veznine ve dile hâkim bir şâirdir. Nazmu’l-Ulûm’da şâirin vezin kusuruna düşmeden dili rahatlıkla kullanması dikkat çekicidir. Bu özellik İshâk Efendi’nin şâirlik gücüne, çok sayıda şiir yazmasına ve yaşadığı dönem olan on yedinci yüzyıla değin Türkçe anlatımdaki gelişmeye de bağlıdır.

  9. Tahsin Ömer’in “Darb-I Mesellerimiz Hakkında Tahlili Tedkikat” Adlı Atasözleri Seçkisi A Selection of Proverbs from Tahsin Ömer’s “Darb-ı Mesellerimiz Hakkında Tahlili Tedkikat”

    Directory of Open Access Journals (Sweden)

    Abdulmuttalip İPEK

    2012-09-01

    foreword. Atasözleri ve deyimler, toplumların uzun süren gözlem, deneyim ve yaşantılarına dayandığından; ait oldukları toplumun yaşama biçiminden düşünce yapısına, değer yargılarından ahlâk anlayışına varıncaya kadar çok değişik konuları içerirler. Bu nedenle bir milletin bütün kültür ve değerler dünyasının özü mesabesinde olan kalıplaşmış sözlerdir. İletişim esnasında kısa, kestirme ve etkili bir anlatımı mümkün kılan atasözleri, aynı zamanda bir milletin felsefesini de yansıtır. Bu bakımdan bu söz varlıklarının bilinmesi ve yaşatılması hayatî önem arz etmektedir. Türk dilinin bilinen en eski sözlüğü olan Divânü Lügati’t-Türk’ten günümüze değin bu söz varlıklarını yaşatma ve kayıt altına alma amacına yönelik önemli sözlükler kaleme alınmıştır. Bunların her biri Türk dili ve kültürü açısından birbirinden değerli kaynaklardır. Bu makalede, yapılan taramalar ve araştırmalar neticesinde, bugüne kadar –bir iki yazı dışında– varlığından söz edilmemiş bir atasözü seçkisi üzerinde durulacaktır. 1337-1340 (M. 1921 yıllarında İstanbul Şehzâdebaşı’ndaki Evkâf Matbaası’nda basılan ve Tahsin Ömer tarafından kaleme alınmış olan “Darb-ı Mesellerimiz Hakkında Tahlîlî Tedkîkât” adlı risalenin, Toronto Üniversitesi Kütüphanesi’nde PN 6505 T8 035 numarada kayıtlı, eski harfli matbu nüshası kısa bir değerlendirme ilave edilerek yeni yazıya çevrilmiştir. Tahsin Ömer’in iki buçuk sayfalık mukaddimede belirttiği üzere bu eser, memleketimizde kullanılan beş bine yakın darbımeselin birer birer tetkiki neticesinde toplanan iki yüze yakın sözün, sahip olduğu manalar itibariyle ayrı ayrı kadrolar halinde tasnif edilip, halkın çeşitli dersler çıkarması ve ibret alması amacıyla kaleme alınmış 16 sayfalık bir risaledir. Pek hacimli olmayan bu risalenin en dikkate değer tarafı müellifinin darb

  10. Reachable Sets of Hidden CPS Sensor Attacks : Analysis and Synthesis Tools

    NARCIS (Netherlands)

    Murguia, Carlos; van de Wouw, N.; Ruths, Justin; Dochain, Denis; Henrion, Didier; Peaucelle, Dimitri

    2017-01-01

    For given system dynamics, control structure, and fault/attack detection procedure, we provide mathematical tools–in terms of Linear Matrix Inequalities (LMIs)–for characterizing and minimizing the set of states that sensor attacks can induce in the system while keeping the alarm rate of the

  11. 2016 Summer California Current Ecosystem CPS Survey (RL1606, EK60)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The cruise sampled the California Current Ecosystem from San Diego, CA to Vancouver Island, BC, CA. Multi-frequency (18-, 38-, 70-, 120-, 200-, and 333-) General...

  12. 2016 Summer California Current Ecosystem CPS Survey (RL1606, EK80)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The cruise sampled the California Current Ecosystem from San Diego, CA to Vancouver Island, BC, CA. Multi-frequency (18-, 38-, 70-, 120-, 200-, and 333-) General...

  13. Recent operation and modifications on the CPS - 50 MeV linac (old linac)

    International Nuclear Information System (INIS)

    Haseroth, H.; Tetu, P.

    1976-01-01

    Mainly to satisfy the requirements of the Booster synchrotron substantial improvements have been achieved on the Linac since 1970. The pulse length was increased to 100 μs and modifications on the rf system and on the pre-injector allowed the production of a stable beam without active feedback. These and further changes to the equipment have had a very beneficial effect on the fault rate. An emittance line providing one measurement per pulse and a spectrometer line furnishing ten spectra per pulse are important tools for beam adjustments. Without additional drastic changes to the machine beams of deuterons and alphas have been produced recently and successfully accelerated by the PS. (author)

  14. Tobacco Use Supplement to the Current Population Survey (TUS-CPS) Data

    Data.gov (United States)

    U.S. Department of Health & Human Services — 1992-1993, 1995-1996, 1998-1999, 2001-2002, 2003, 2006-2007, 2010-2011, 2014-2015. Centers for Disease Control and Prevention (CDC). State Tobacco Activities...

  15. Data Series Generation for CPS Plants Simulation; Generacion de Series para Simulacion de Centrales Termosolares

    Energy Technology Data Exchange (ETDEWEB)

    Ibanez, G.; Valenzuela, R. X.; Ramirez, L.; Polo, J.

    2014-02-01

    Due to the problems with the environment and other issues arising from the use of oil as the main source of energy, such as unstable politics and economics, there has been a growing interest in the development of alternative forms of energy over the last few years. In this field, the sun is a fundamental element, since any form of existing energy derives from it, directly or indirectly. Taking in to consideration all of these renewable energies, we have decided to focus on solar thermal energy, seeing as it will play a vital role in the future particularly in countries such as Spain that have great solar potential. Amid this form of renewable energy, the parabolic cylinder concentrator power plants are technologies with one of the most promising futures. Power plants with sufficient technological developments to compete with the other forms of energies and that have an extensive margin for improvement. These power plants are the subject of the investigations carried out in this project. This project will try to establish and standardize some of the necessary procedures for the process of data prior to the simulation of energy with these types of power plants. The final objective is to help create a regulation where all these procedures are gathered together, and one that can be used as a guide for future investigations on the viability of these power plants. To achieve this, this project is comprised of various phases where different necessary investigations will be carried out in order to define the different points of the regulation. Firstly, the different casuistries will be investigated when analyzing the behavior of the estimated input data. At this stage, the selected variable (global or direct radiation), as well as the procedure used for the generation of the Monthly Reference Value, will be taken in to account, differentiating it in to two different typologies. The best method for the adjustment of the estimated data obtained from the satellite images will also be investigated, proposing the incorporation of a new method for it, as well as trying to determine whether it is equivalent to the one already established. Lastly, a simulation will be completed with the estimated data already processed in order to evaluate the influence of different alternatives and methods set out in the results, allowing for the comparison of these results with other simulations carried out with the measured data. (Author)

  16. 78 FR 77646 - Proposed Information Collection; Comment Request; Current Population Survey (CPS) Basic...

    Science.gov (United States)

    2013-12-24

    ... age, marital status, gender, Armed Forces status, education, race, origin, and family income. We use... sponsor the basic monthly survey. The Census Bureau also prepares and conducts all the field work. At the.... Some of the information within that portion includes employment status, number of hours worked, job...

  17. 75 FR 78676 - Proposed Information Collection; Comment Request; Current Population Survey (CPS) Basic...

    Science.gov (United States)

    2010-12-16

    ... age, marital status, gender, Armed Forces status, education, race, origin, and family income. We use... sponsor the basic monthly survey. The Census Bureau also prepares and conducts all the field work. At the.... Some of the information within that portion includes employment status, number of hours worked, job...

  18. Study on perception and control layer of mine CPS with mixed logic dynamic approach

    Science.gov (United States)

    Li, Jingzhao; Ren, Ping; Yang, Dayu

    2017-01-01

    Mine inclined roadway transportation system of mine cyber physical system is a hybrid system consisting of a continuous-time system and a discrete-time system, which can be divided into inclined roadway signal subsystem, error-proofing channel subsystems, anti-car subsystems, and frequency control subsystems. First, to ensure stable operation, improve efficiency and production safety, this hybrid system model with n inputs and m outputs is constructed and analyzed in detail, then its steady schedule state to be solved. Second, on the basis of the formal modeling for real-time systems, we use hybrid toolbox for system security verification. Third, the practical application of mine cyber physical system shows that the method for real-time simulation of mine cyber physical system is effective.

  19. 76 FR 3610 - Proposed Information Collection; Comment Request; Current Population Surveys (CPS)-Housing...

    Science.gov (United States)

    2011-01-20

    ... HVS data to analyze market trends and for economic forecasting. II. Method of Collection Field... questions) and BC-1428RV (Brochure--The U.S. Census Bureau Respects Your Privacy and Keeps Your Personal...

  20. 77 FR 27020 - Proposed Information Collection; Comment Request; Current Population Survey (CPS) Voting and...

    Science.gov (United States)

    2012-05-08

    ... distinct from independent surveys, media polls, or other outside agencies. Federal, state, and local election officials use these data to formulate policies relating to the voting and registration process. College institutions, political party committees, research groups, and other private organizations also...

  1. The easy ADL home: A physical-virtual approach to domestic living

    DEFF Research Database (Denmark)

    Surie, Dipak; Pederson, Thomas; Janlert, Lars-Erik

    2010-01-01

    Smart environments worthy of the name need to capture, interpret, and support human activities that take place within their realms. Most existing efforts tend to focus on either real world activities or activities taking place in the virtual world accessed through digital devices. However......, as digital computation continues to permeate our everyday real world environments, and as the border between physical and digital continues to blur for the human agents acting in these environments, we need system design approaches that can cope with human activities that span the physical-virtual gap...

  2. Temporal and reciprocal relationship between IADL/ADL disability and depressive symptoms in late life

    NARCIS (Netherlands)

    Ormel, J; Rijsdijk, FV; Sullivan, M; van Sonderen, E; Kempen, GIJM

    A strong association between functional disability and depressive symptoms in older people has frequently been reported. Some studies attribute this association to the disabling effects of depression, others to the depressogenic effects of physical health-related disability. The authors examined the

  3. Adlî Tıpta Giysi İncelemesinin Yeri

    Directory of Open Access Journals (Sweden)

    Muhammet Can

    2005-08-01

    Full Text Available Fiziksel deliller, adli olayın aydınlatılmasında ve orijin tayininde çok önemli bir yere sahiptir. Ateşli silahlar ve çeşitli aletler (kesici, kesici-delici, delici vb. ile yaralanma ve öldürme olaylarında, ölen ve/veya yaralananın olay anında üzerinde bulunan giysilerin fiziksel ve kimyasal incelemesi, olayın adli ve tıbbi sonuçları açısından önemlidir. Çalışmamızda 1995-1999 yılları arasında Adli Tıp Kurumu-Fizik İncelemeler İhtisas Dairesi’nde giysi incelemesi ile ilgili olarak düzenlenen raporlar yapılandırılmış bir değerlendirme formuna göre taranmıştır. İnceleme için gönderilen 1172 adet dosyanın %6 Tinde atış mesafesi, %18’inde giysi tetkiki, %4’ünde aletin türü ile ilgili soruların fiziksel delil elde etmek yönünde öne çıktığı görülmüştür. Giysilerin elde ediliş ve gönderilişi sırasında aksaklıklar saptanmış, bazı dosyalarda incelemesi istenen giysilerin dosya ve otopsi raporu bulunmadan gönderildiği tespit edilmiştir. Sonuç olarak, giysi incelemesi istenen dosyalarda, her aşamada uygun prosedürlerin uygulanması gerekliliği ortaya konmuştur. Anahtar kelimeler: Adli tıp, fiziksel delil, giysi incelemesi, atış mesafesi, aletin türü.

  4. Distributed co-simulation of embedded control software with exhaust gas recirculation water handling system using INTO-CPS

    DEFF Research Database (Denmark)

    Pedersen, Nicolai; Lausdahl, Kenneth; Sanchez, Enrique Vidal

    2017-01-01

    properties is often desirable. However, it is non-trivial to be able to combine such different models of different constituent elements. In order to reduce the need for expensive tests on the real system it is advantageous to be able to combine such heterogeneous models in a joint co-simulation in order...

  5. The Impact of Survey and Response Modes on Current Smoking Prevalence Estimates Using TUS-CPS: 1992-2003

    Directory of Open Access Journals (Sweden)

    Julia Soulakova

    2009-12-01

    Full Text Available This study identified whether survey administration mode (telephone or in-person and respondent type (self or proxy result in discrepant prevalence of current smoking in the adult U.S. population, while controlling for key sociodemographic characteristics and longitudinal changes of smoking prevalence over the 11-year period from 1992-2003. We used a multiple logistic regression analysis with replicate weights to model the current smoking status logit as a function of a number of covariates. The final model included individual- and family-level sociodemographic characteristics, survey attributes, and multiple two-way interactions of survey mode and respondent type with other covariates. The respondent type is a significant predictor of current smoking prevalence and the magnitude of the difference depends on the age, sex, and education of the person whose smoking status is being reported. Furthermore, the survey mode has significant interactions with survey year, sex, and age. We conclude that using an overall unadjusted estimate of the current smoking prevalence may result in underestimating the current smoking rate when conducting proxy or telephone interviews especially for some sub-populations, such as young adults. We propose that estimates could be improved if more detailed information regarding the respondent type and survey administration mode characteristics were considered in addition to commonly used survey year and sociodemographic characteristics. This information is critical given that future surveillance is moving toward more complex designs. Thus, adjustment of estimates should be contemplated when comparing current smoking prevalence results within a given survey series with major changes in methodology over time and between different surveys using various modes and respondent types.

  6. Placement Stability, Cumulative Time in Care, and Permanency: Using Administrative Data from CPS to Track Placement Trajectories.

    Science.gov (United States)

    Hélie, Sonia; Poirier, Marie-Andrée; Esposito, Tonino; Turcotte, Daniel

    2017-11-17

    Objectives : The Quebec Youth Protection Act was amended in 2007. The main goal of this reform was to improve placement stability for children who are removed from their home for their protection. Among several legal provisions introduced was the establishment of maximum age-specific durations of out-of-home care, after which a plan must be established to provide stability for children placed in substitute care by finding permanent homes for them. The purpose of this study is (1) to examine trends in placement use and placement stability since the reform and (2) to document the current frequency of each type of placement setting, the cumulative time in care before the exit to permanency, and the sustainability of the permanency outcome. Methods: The study relies on 3 entry cohorts of all children investigated who received protection measures in the province of Quebec during 3 specific time frames before and after the reform ( n = 9620, 8676, 8425). Cohorts were observed for a period varying from 3 to 4 years. Administrative data from all 16 child protection agencies were used to track placement trajectory indicators and to compare cohorts. Results : There has been a decrease in the proportion of children receiving protection measures who were placed in care since the reform, and placement in kinship care has become more frequent among children placed. Placement stability improved slightly after the reform. Overall, for infants, the most frequent type of permanency attained is adoption, while reunification is the option most often indicated for older children. Some children are at a greater risk of experiencing unstable placement trajectories: young children have a high rate of reunification breakdown, some wait a long time to be adopted, and adolescents are frequently removed from the substitute care setting where they were supposed to stay until the age of 18. Conclusions : The results suggest interesting avenues for policy makers and service providers to improve the stability of placement trajectories. Advantages and disadvantages of administrative data are discussed.

  7. Placement Stability, Cumulative Time in Care, and Permanency: Using Administrative Data from CPS to Track Placement Trajectories

    Directory of Open Access Journals (Sweden)

    Sonia Hélie

    2017-11-01

    Full Text Available Objectives: The Quebec Youth Protection Act was amended in 2007. The main goal of this reform was to improve placement stability for children who are removed from their home for their protection. Among several legal provisions introduced was the establishment of maximum age-specific durations of out-of-home care, after which a plan must be established to provide stability for children placed in substitute care by finding permanent homes for them. The purpose of this study is (1 to examine trends in placement use and placement stability since the reform and (2 to document the current frequency of each type of placement setting, the cumulative time in care before the exit to permanency, and the sustainability of the permanency outcome. Methods: The study relies on 3 entry cohorts of all children investigated who received protection measures in the province of Quebec during 3 specific time frames before and after the reform (n = 9620, 8676, 8425. Cohorts were observed for a period varying from 3 to 4 years. Administrative data from all 16 child protection agencies were used to track placement trajectory indicators and to compare cohorts. Results: There has been a decrease in the proportion of children receiving protection measures who were placed in care since the reform, and placement in kinship care has become more frequent among children placed. Placement stability improved slightly after the reform. Overall, for infants, the most frequent type of permanency attained is adoption, while reunification is the option most often indicated for older children. Some children are at a greater risk of experiencing unstable placement trajectories: young children have a high rate of reunification breakdown, some wait a long time to be adopted, and adolescents are frequently removed from the substitute care setting where they were supposed to stay until the age of 18. Conclusions: The results suggest interesting avenues for policy makers and service providers to improve the stability of placement trajectories. Advantages and disadvantages of administrative data are discussed.

  8. Do state minimum markup/price laws work? Evidence from retail scanner data and TUS-CPS.

    Science.gov (United States)

    Huang, Jidong; Chriqui, Jamie F; DeLong, Hillary; Mirza, Maryam; Diaz, Megan C; Chaloupka, Frank J

    2016-10-01

    Minimum markup/price laws (MPLs) have been proposed as an alternative non-tax pricing strategy to reduce tobacco use and access. However, the empirical evidence on the effectiveness of MPLs in increasing cigarette prices is very limited. This study aims to fill this critical gap by examining the association between MPLs and cigarette prices. State MPLs were compiled from primary legal research databases and were linked to cigarette prices constructed from the Nielsen retail scanner data and the self-reported cigarette prices from the Tobacco Use Supplement to the Current Population Survey. Multivariate regression analyses were conducted to examine the association between MPLs and the major components of MPLs and cigarette prices. The presence of MPLs was associated with higher cigarette prices. In addition, cigarette prices were higher, above and beyond the higher prices resulting from MPLs, in states that prohibit below-cost combination sales; do not allow any distributing party to use trade discounts to reduce the base cost of cigarettes; prohibit distributing parties from meeting the price of a competitor, and prohibit distributing below-cost coupons to the consumer. Moreover, states that had total markup rates >24% were associated with significantly higher cigarette prices. MPLs are an effective way to increase cigarette prices. The impact of MPLs can be further strengthened by imposing greater markup rates and by prohibiting coupon distribution, competitor price matching, and use of below-cost combination sales and trade discounts. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/.

  9. Fabrication of a PANI/CPs composite material: a feasible method to enhance the photocatalytic activity of coordination polymers.

    Science.gov (United States)

    Xu, Xin-Xin; Cui, Zhong-Ping; Qi, Ji; Liu, Xiao-Xia

    2013-03-21

    To improve the photocatalytic activity of a coordination polymer in the visible light region, polyaniline (PANI) was loaded onto its surface through a facile in situ chemical oxidation polymerization process. The resulting PANI loaded coordination polymer composite materials with excellent stability exhibit significantly higher photocatalytic activities than the pure coordination polymer photocatalyst on the degradation of methyl orange (MO) under visible light irradiation. This enhancement can be ascribed to the introduction of PANI on the surface of the coordination polymer, which leads to efficient separation of photogenerated electron-hole pairs as well as a significant expansion of the photoresponse region. Finally, we discussed the influence of acidity on the morphology and photocatalytic activity of the composite material. An optimal condition to obtain the PANI loaded coordination polymer composite material with excellent photocatalytic activity has been obtained.

  10. Distributed co-simulation of embedded control software with exhaust gas recirculation water handling system using INTO-CPS

    DEFF Research Database (Denmark)

    Pedersen, Nicolai; Lausdahl, Kenneth; Sanchez, Enrique Vidal

    2017-01-01

    to reduce the overall costs of validation. This paper demonstrates how this can be achieved for a commercial system developed by MAN Diesel & Turbo using a newly developed tool chain based on the Functional Mock-up Interface standard for co-simulation supporting different operating systems. The generality...

  11. Placement Stability, Cumulative Time in Care, and Permanency: Using Administrative Data from CPS to Track Placement Trajectories

    Science.gov (United States)

    Hélie, Sonia; Poirier, Marie-Andrée; Esposito, Tonino; Turcotte, Daniel

    2017-01-01

    Objectives: The Quebec Youth Protection Act was amended in 2007. The main goal of this reform was to improve placement stability for children who are removed from their home for their protection. Among several legal provisions introduced was the establishment of maximum age-specific durations of out-of-home care, after which a plan must be established to provide stability for children placed in substitute care by finding permanent homes for them. The purpose of this study is (1) to examine trends in placement use and placement stability since the reform and (2) to document the current frequency of each type of placement setting, the cumulative time in care before the exit to permanency, and the sustainability of the permanency outcome. Methods: The study relies on 3 entry cohorts of all children investigated who received protection measures in the province of Quebec during 3 specific time frames before and after the reform (n = 9620, 8676, 8425). Cohorts were observed for a period varying from 3 to 4 years. Administrative data from all 16 child protection agencies were used to track placement trajectory indicators and to compare cohorts. Results: There has been a decrease in the proportion of children receiving protection measures who were placed in care since the reform, and placement in kinship care has become more frequent among children placed. Placement stability improved slightly after the reform. Overall, for infants, the most frequent type of permanency attained is adoption, while reunification is the option most often indicated for older children. Some children are at a greater risk of experiencing unstable placement trajectories: young children have a high rate of reunification breakdown, some wait a long time to be adopted, and adolescents are frequently removed from the substitute care setting where they were supposed to stay until the age of 18. Conclusions: The results suggest interesting avenues for policy makers and service providers to improve the stability of placement trajectories. Advantages and disadvantages of administrative data are discussed. PMID:29149070

  12. Niveles de dependencia y utilización de servicios en los hospitales psiquiátricos de Aragón Dependency levels and health care services' utilization in psychiatric hospitals in Aragon (Spain

    Directory of Open Access Journals (Sweden)

    Marcos de Miguel

    2004-06-01

    assess their dependency levels, and to analyze health care services' utilization by these patients. Methods: We performed a cross-sectional study between July 1 and November 31. The questionnaire used was the Resident Assessment Instrument- Mental Health (RAI-MH. The sample consisted of 437 patients living in public psychiatric hospitals in Aragon. These hospitals provide care to chronically mentally ill patients and to patients undergoing rehabilitation. The Resource Utilization Group (RUG-I system was used to classify patients by their dependency levels for activities of daily life (ADL.Results: Of the 437 patients, 259 (59.3% were men with a mean age of 62.2 years. A total of 82.1% of the patients were classified as RUG-I group 1. Patients in groups 1 and 2 required more formal health care services. At least one visit by a psychiatrist was required by 25.3% of patients in group 1 and by 15.2% of those in group 2 compared with no visits by the other groups. Nursing interventions were more frequently required by patients in the more dependent groups. All of the of patients in groups 2 to 8 needed daily physical assistance for ADL vs. 26.3% of those in group 1. In the multivariate analysis, predictive variables were the hospital and type of unit. Conclusions: There is wide variation in health care services' utilization by patients living in psychiatric hospitals, which is related to dependency levels. Many psychiatric patients do not need formal psychiatric care. Health care professionals should assess the real needs of patients to provide each of them with appropriate care.

  13. Egocentric interaction as a tool for designing ambient ecologies – The case of the easy ADL ecology

    DEFF Research Database (Denmark)

    Surie, Dipak; Janlert, Lars-Erik; Pederson, Thomas

    2012-01-01

    ambient intelligence could be realised. This work describes such an ambient ecological system comprising of a set of smart everyday objects, a personal activity-centric middleware, a set of mock-up ubiquitous computing applications and a human agent within a living laboratory home environment......Ambient intelligence is a human-centered vision characterized by the seamless integration of information, communication, sensing and actuation, and interface technologies for supporting human agents with their everyday activities. There are many challenges to address including the need...... for an interaction paradigm that encompasses the multiple dimensions of a human agent and their environment. This work describes a human-centered interaction paradigm referred to as the egocentric interaction paradigm that considers a human agents body and mind as a centre of reference to which all interaction...

  14. The tool in the brain: apraxia in ADL. Behavioral and neurological correlates of apraxia in daily living

    OpenAIRE

    Bienkiewicz, Marta M. N.; Brandi, Marie-Luise; Goldenberg, Georg; Hughes, Charmayne M. L.; Hermsdoerfer, Joachim

    2014-01-01

    Humans differ from other animals in the way they can skilfully and precisely operate or invent tools to facilitate their everyday life. Tools have dominated our home, travel and work environment, becoming an integral step for our motor skills development. What happens when the part of the brain responsible for tool use is damaged in our adult life due to a cerebrovascular accident? How does daily life change when we lose the previously mastered ability to make use of the objects around us? Ho...

  15. Review and meta-anlaysis of the relationship between physical activity and adl disability in older adults

    NARCIS (Netherlands)

    Tak, E.; Kuiper, R.; Chorus, A.; Hopman-Rock, M.

    2012-01-01

    Abstract for the International Society for Aging and Physical activity's 8th World Congress on Aging and Physical Activity: A celebration of Diversity and Inclusion in Active Ageing, August 13-17 2012.

  16. Review of Effects of Physical Activity on Strength, Balance, Mobility and ADL Performance in Elderly Subjects with Dementia

    NARCIS (Netherlands)

    Blankevoort, Christiaan G.; van Heuvelen, Marieke J. G.; Boersma, Froukje; Luning, Helga; de Jong, Jeltsje; Scherder, Erik J. A.

    2010-01-01

    Background/Aims: Elderly individuals with dementia are vulnerable for a decline in physical functioning and basic activities of daily living (BADL) which can lead to a decline in autonomy and participation. This study reviews the effect of physical activity on physical functioning and BADL in

  17. The use of hydrogel materials Coletex-ADL and Colegel in the treatment of purulent frontal sinusitis

    OpenAIRE

    N.А. Khar’kova; М.Yu. Gerasimenko; Е.А. Egorova

    2014-01-01

    The aim of the investigation was to assess the treatment efficacy of purulent frontal sinusitis including local use of Russian hydrogel materials with antiseptic, analgesic and hemostatic properties in combination with sinus obliteration by osteoplastic materials and physiotherapy. Materials and Methods. The study involved 20 subjects who had been operated on for destructive changes of frontal sinus walls due to purulent frontitis. For local treatment we used Russian depot-materials: hydr...

  18. The effects of the Green House nursing home model on ADL function trajectory: A retrospective longitudinal study.

    Science.gov (United States)

    Yoon, Ju Young; Brown, Roger L; Bowers, Barbara J; Sharkey, Siobhan S; Horn, Susan D

    2016-01-01

    Growing attention in the past few decades has focused on improving care quality and quality of life for nursing home residents. Many traditional nursing homes have attempted to transform themselves to become more homelike emphasizing individualized care. This trend is referred to as nursing home culture change in the U.S. A promising culture change nursing home model, the Green House nursing home model, has shown positive psychological outcomes. However, little is known about whether the Green House nursing home model has positive effects on physical function compared to traditional nursing homes. To examine the longitudinal effects of the Green House nursing home model by comparing change patterns of activities of daily living function over time between Green House home residents and traditional nursing home residents. A retrospective longitudinal study. Four Green House organizations (nine Green House units and four traditional units). A total of 242 residents (93 Green House residents and 149 traditional home residents) who had stayed in the nursing home at least 6 months from admission. The outcome was activities of daily living function, and the main independent variable was the facility type in which the resident stayed: a Green House or traditional unit. Age, gender, comorbidity score, cognitive function, and depressive symptoms at baseline were controlled. All of these measures were from a minimum dataset. Growth curve modeling and growth mixture modeling were employed in this study for longitudinal analyses. The mean activities of daily living function showed deterioration over time, and the rates of deterioration between Green House and traditional home residents were not different over time. Four different activities of daily living function trajectories were identified for 18 months, but there was no statistical difference in the likelihood of being in one of the four trajectory classes between the two groups. Although Green House nursing homes are considered to represent an innovative model changing the nursing home environment into more person-centered, this study did not demonstrate significant differences in activities of daily living function changes for residents in the Green House nursing homes compared to traditional nursing homes. Given that the Green House model continues to evolve as it is being implemented and variations within and across Green House homes are identified, large-scale longitudinal studies are needed to provide further relevant information on the effects of the Green House model. Copyright © 2015 Elsevier Ltd. All rights reserved.

  19. Tom Stoppard'ın Rosencrantz ve Guildenstern Öldüler Adlı Oyununda Mizah ve Kader

    OpenAIRE

    Erkan, Ayça Ülker

    2016-01-01

    Bu çalışmanın amacı karakterlerin kimlik arayışından kaynaklanan fiziksel mizahı tartışmak ve oyundaki ölüm/şans/kader/gerçeklik/yanılsama gibi temaların Rosencrantz ve Guildenstern’nin varoluşçu hayatlarında nasıl işlediğini göstermektir. Mizah, bu trajikomedinin analiz edilmesinde önemli bir rol oynar. Absürd Tiyatro, insanlık durumundaki saçmalığı ifade eder, rasyonel aygıtların kullanımını terk eder, insanın trajik kaybolmuşluk duygusunu yansıtır ve insanlık durumu olan hayat ve ölümle il...

  20. IoT gateways, cloud and the last mile for energy efficiency and sustainability in the era of CPS expansion: "A bot is irrigating my farm.. "

    Science.gov (United States)

    Papageorgas, Panagiotis G.; Agavanakis, Kyriakos; Dogas, Ioannis; Piromalis, Dimitrios D.

    2018-05-01

    A cloud-based architecture is presented for the internetworking of sensors and actuators through a universal gateway, network server and application user interface design. The proposed approach targets to Energy Efficiency and sustainability in a holistic way, by integrating an open-source test bed prototype based on long-range low-bandwidth wireless networking technology for sensing and actuation as the elementary block of a viable, cost-effective and reliable solution. The prototype presented is capable of supporting both sensors and actuators, processing data locally and transmitting the results of the imposed computations to a higher level node. Additionally, it is combined with a service-oriented architecture and involves publish/subscribe middleware protocols and cloud technology to confront with the system needs in terms of data volume and processing power. In this context, the integration of instant message (chat) services is demonstrated so that they can be part of an emerging global-scope eco-system of Cyber-Physical Systems to support a wide variety of IoT applications, with strong advantages such as usability, scalability and security, while adopting a unified gateway design and a simple - yet powerful - user interface.

  1. Project, fabrication, assembly and tests of different prototypes for CPS compound parabolic solar collectors; Projeto, fabricacao, montagem e testes de diferentes prototipos de coletores solares parabolicos compostos CPCs

    Energy Technology Data Exchange (ETDEWEB)

    Neto, Jose H.M. [Centro Federal de Educacao Tecnologica de Minas Gerais (CEFET), Belo Horizonte, MG (Brazil). Dept. de Engenharia Mecanica]. E-mail: henrique@daem.des.cefemg.br

    2000-07-01

    This work presents the results of the experiment involving the design, fabrication, assembly and tests of composite parabolic solar collectors prototypes with acceptance half-angles of 3 deg C, 6.5 deg C, 11 deg C, 14 deg C and 19.5 deg C of the tube type absorber and 14 deg C rectangular absorber. Field test were performed on all the prototypes for determination of thermal efficiency, time constants and optical efficiencies represented by the modified incidence angles. Tests were performed for the determination of the heat transfer global coefficients on each prototype. (author)

  2. VES PANEL (by invitation): Advancement and Enhanced Integration of Digital Technology Systems, VR Applications, CPS-Systems and Tools for Design Engineering

    NARCIS (Netherlands)

    Wendrich, Robert E.; Lim, Theodore; Baalsrud Hauge, Jannicke; Vitali, Andrea

    2018-01-01

    The purpose of this VES panel is to encourage discussion and exchange of views about current and new trends for Virtual and Immersive/Blended Systems and the transference of knowledge over multiple domains. As the market and/or industrial interest in virtual environments increase, new technologies

  3. Validation of the CPS+EG and Neo-Bioscore staging systems after preoperative systemic therapy for breast cancer in a single center in China.

    Science.gov (United States)

    Xu, Ling; Duan, Xuening; Zhou, Bin; Liu, Yinhua; Ye, Jingming; Liu, Zhaorui; Ma, Chao; Zhang, Hong; Zhang, Shuang; Zhang, Lanbo; Zhao, Jianxin; Cheng, Yuanjia

    2018-04-17

    Prognostic assessment after preoperative systemic therapy (PST) plays a vital role in determining treatment in breast cancer patients. Many researchers have sought to develop a system to quantitate residual tumor and its correlation with prognosis after PST. This retrospective study validated the CPS + EG staging system and Neo-Bioscore in a single center in China. Data from patients with non-metastatic primary breast cancer who were treated with PST and surgery from Jan. 2008 to Dec. 2014 at the Breast Disease Center of Peking University First Hospital, China, were reviewed. DFS, DSS and OS were calculated using the K-M curve and AUC. Multivariate analysis was used for a Cox proportional hazards model. All calculations were performed with SAS 9.4. A total of 403 patients were enrolled in this study. The median follow-up period was 45 (range 11-107) months. The five-year DFS, DSS and OS rates were 86.4%, 91.2% and 90.5%, respectively. The CS, PS, CPS + EG staging system and Neo-Bioscore stratified patients according to DFS, DSS, and OS after PST, with all P values < 0.0001. The CPS + EG staging system and Neo-Bioscore stratified prognosis after PST better than CS. HER2-positive patients without trastuzumab treatment had obviously worse DFS and OS than other subgroups with different HER2 statuses that scored a 3 in the Neo-Bioscore system. The CPS + EG staging system and Neo-Bioscore can improve prognostic prediction in non-pCR breast cancer patients after PST and, provided unfavorable prognostic factors such as insufficient treatment are incorporated, will have broader clinical applicability. Copyright © 2018 Elsevier Ltd. All rights reserved.

  4. Data Series Generation for CPS Plants Simulation from Measurement Data; Generacion de Series de Datos para Simulacion de Centrales Termosolares Basadas en Datos Medidos

    Energy Technology Data Exchange (ETDEWEB)

    Mora, D. E.; Valenzuela, R. X.; Ramirez, L.; Polo, J.

    2014-02-01

    This project studies the impact of new regulations for solar thermal power plants purporting to be made in the future. In this document we analyze each of the points of the standard PROCEDURE FOR GENERATING A REPRESENTATIVE SOLAR YEAR is expected to be approved in a short period of time. The main purpose of this standard is to establish a series of solar radiation data called Representative Solar Year (RSY), which are hourly data for a full year that characterize the site where the plant will be installed. For this there is the possibility of generating the RSY by two methods, the first is to use estimates of solar radiation and the second use solar radiation data measured at the site. The second case is the one that will be addressed in the following pages. According to the methodology set out in the rule for generating RSY, through measured data, develops each of the points which can obtain the final result an estimate of the energy produced by the plant. First we calculate a Monthly Reference Values (MRV) of solar radiation as a basis for generating the RSY. The following is taken measured data sets must overcome quality and validation processes. The next step is to make an accommodation between the MRV and sets measured by a change of days, following the directions of the standard. The end result of this process we obtain the respective RSY that for purposes of this study will be entered into a simulation program that calculates the energy produced by a solar thermal plant. In this way we analyze and compare the energy produced by the plant with real data and RSY data obtained. (Author)

  5. Dense ion clouds of 0.1 − 2 keV ions inside the CPS-region observed by Astrid-2

    Directory of Open Access Journals (Sweden)

    O. Norberg

    Full Text Available Data from the Astrid-2 satellite taken between April and July 1999 show several examples of dense ion clouds in the 0.1–2 keV energy range inside the inner mag-netosphere, both in the northern and southern hemispheres. These inner magnetospheric ion clouds are found predomi-nantly in the early morning sector, suggesting that they could have originated from substorm-related ion injections on the night side. However, their location and density show no cor-relation with Kp, and their energy-latitude dispersion is not easily reproduced by a simple particle drift model. There-fore, these ion clouds are not necessarily caused by substorm-related ion injections. Alternative explanations for the ion clouds are the direct solar wind injections and up-welling ions from the other hemisphere. These explanations do not, however, account for all of the observations.Key words. Magnetospheric physics (energetic particles, trapped; magnetospheric configuration and dynamics; storm and substorms

  6. Effects of high-intensity exercise and protein supplement on muscle mass in ADL dependent older people with and without malnutrition: a randomized controlled trial.

    Science.gov (United States)

    Carlsson, M; Littbrand, H; Gustafson, Y; Lundin-Olsson, L; Lindelöf, N; Rosendahl, E; Håglin, L

    2011-08-01

    Loss of muscle mass is common among old people living in institutions but trials that evaluate interventions aimed at increasing the muscle mass are lacking. Objective, participants and intervention: This randomized controlled trial was performed to evaluate the effect of a high-intensity functional exercise program and a timed protein-enriched drink on muscle mass in 177 people aged 65 to 99 with severe physical or cognitive impairments, and living in residential care facilities. Three-month high-intensity exercise was compared with a control activity and a protein-enriched drink was compared with a placebo drink. A bioelectrical impedance spectrometer (BIS) was used in the evaluation. The amount of muscle mass and body weight (BW) were followed-up at three and six months and analyzed in a 2 x 2 factorial ANCOVA, using the intention to treat principle, and controlling for baseline values. At 3-month follow-up there were no differences in muscle mass and BW between the exercise and the control group or between the protein and the placebo group. No interaction effects were seen between the exercise and nutritional intervention. Long-term negative effects on muscle mass and BW was seen in the exercise group at the 6-month follow-up. A three month high-intensity functional exercise program did not increase the amount of muscle mass and an intake of a protein-enriched drink immediately after the exercise did not induce any additional effect on muscle mass. There were negative long-term effects on muscle mass and BW, indicating that it is probably necessary to compensate for an increased energy demand when offering a high-intensity exercise program.

  7. Rizâeddin b. Fahreddin ve Kütüb-i Sitte ve Müellifleri adlı eseri

    OpenAIRE

    KHAZİEV, Rinat

    2015-01-01

    Tez bir Girişten ve üç bölümden oluşmaktadır. Girişte tezin içerdiği bilgiler ve hazırlanmasında izlenen yöntem hakkında bilgiler verilmiştir.Tezin birinci bölümünde Rizâeddin b. Fahreddin’in hayatına dair bilgiler sunulmuştur. Onun şahsiyeti, âlimliği, başmuharrirliği ve sosyal faaliyetleri gösterilmiştir. Diğer taraftan da onun hayatı, ilmi tahsili, hocaları ve eserleri ele alınmıştır.Araştırmanın ikinci bölümde Rizâeddin b. Fahreddin’n Hadis ilmine bakışı ve yaklaşımı tahlil edilm...

  8. Nicole Krauss’un Aşkın Tarihi Adlı Romanında Tarihi İzlekler

    OpenAIRE

    KALAY, Faruk

    2014-01-01

    Modern edebiyatta önemli Yahudi Amerikan yazarlarından olan Nicole Krauss Yahuditoplumundaki yabancılaşma, yalnızlık ve göç konularına değinir. Başarılı romanı olanAşkın Tarihi II. Dünya Savaşı süresince Holokost’a maruz kalan ve etkilerini hissedenYahudi karakterle ilgilidir. Tarihle bütünleşen bu karakterler gerçek hayattakiinsanlardan ve olaylardan esinlenmiştir. Krauss romanında postmodern teknikleri dekullanır. Örneğin iç içe anlatım tekniği okuyucuya romanın kurgusal mı yoksa gerçek mio...

  9. Abuso sexual intrafamiliar o trauma por divorcio violento: Cámara Gesell. estudio de los deseos y defensas según ADL-M Y AD-R

    OpenAIRE

    Nudel, Cristina R

    2015-01-01

    El uso del Algoritmo David Liberman desempeños motrices (M) y relatos (R) para evaluar las declaraciones en Cámara Gesell, permite una exploración profunda de las marcas de trauma sexual cuando estas no llegan a expresarse mediante el discurso hablado. Esto nos permite cuantificar y realizar interpretaciones cualitativas de los daños, en relación con esas situaciones específicas, lo cual es algo que hasta el momento no tuvo lugar en las dinámicas de declaraciones judiciales. De este modo, pod...

  10. Faslün Fî Usûli'l-İmân Adlı Risale ve Maturidi'ye Aidiyeti

    Directory of Open Access Journals (Sweden)

    Ahmet Ak

    2015-11-01

    Full Text Available In this article, a treatise “entitled “fasl fi usul al-iman” that shows some similarities to to the Maturidite views will be dealt with as to whether it belongs to al-Maturidi or not. Therefore, the views put forth in the treatise have been compared with that of Kitab al-Tawhid and Ta’wilat al-Qur’ân. As a result, it hasa been concluded that the terms used in the treatise such as al-irâda al-juz’iyya, al-irâda al-kulliyya and al-ba‘th ba‘d al-mawt have not been used by al-Maturidi in his works. Thus, it has been argued that the treatise in question was written by a Maturidite school long after the date of Maturidi. Besides, it has been emphasized that this treatise sets an example for the fact that the Asharite views had found their places in the Maturidite sources

  11. Promoting ADL independence in vulnerable, community-dwelling older adults: a pilot RCT comparing 3-Step Workout for Life versus resistance exercise

    Directory of Open Access Journals (Sweden)

    Liu C

    2017-07-01

    Full Text Available Chiung-ju Liu,1,2 Huiping Xu,3,4 NiCole R Keith,2,4,5 Daniel O Clark2,4,6 1Department of Occupational Therapy, Indiana University School of Health and Rehabilitation Sciences, 2Indiana University Center for Aging Research, 3Department of Biostatistics, Indiana University Richard M. Fairbanks School of Public Health, 4Regenstrief Institute, Inc., 5Department of Kinesiology, Indiana University School of Physical Education and Tourism Management, 6Indiana University School of Medicine, Indianapolis, IN, USA Background: Resistance exercise is effective to increase muscle strength for older adults; however, its effect on the outcome of activities of daily living is often limited. The purpose of this study was to examine whether 3-Step Workout for Life (which combines resistance exercise, functional exercise, and activities of daily living exercise would be more beneficial than resistance exercise alone. Methods: A single-blind randomized controlled trial was conducted. Fifty-two inactive, community-dwelling older adults (mean age =73 years with muscle weakness and difficulty in activities of daily living were randomized to receive 3-Step Workout for Life or resistance exercise only. Participants in the 3-Step Workout for Life Group performed functional movements and selected activities of daily living at home in addition to resistance exercise. Participants in the Resistance Exercise Only Group performed resistance exercise only. Both groups were comparable in exercise intensity (moderate, duration (50–60 minutes each time for 10 weeks, and frequency (three times a week. Assessment of Motor and Process Skills, a standard performance test on activities of daily living, was administered at baseline, postintervention, and 6 months after intervention completion.Results: At postintervention, the 3-Step Workout for Life Group showed improvement on the outcome measure (mean change from baseline =0.29, P=0.02, but the improvement was not greater than the Resistance Exercise Only Group (group mean difference =0.24, P=0.13. However, the Resistance Exercise Only Group showed a significant decline (mean change from baseline =–0.25, P=0.01 6 months after the intervention completion. Meanwhile, the superior effect of 3-Step Workout for Life was observed (group mean difference =0.37, P<0.01.Conclusion: Compared to resistance exercise alone, 3-Step Workout for Life improves the performance of activities of daily living and attenuates the disablement process in older adults. Keywords: activities of daily living, aging in place, resistance exercise, functional exercise, disablement process 

  12. Effects of gross motor function and manual function levels on performance-based ADL motor skills of children with spastic cerebral palsy

    OpenAIRE

    Park, Myoung-Ok

    2017-01-01

    [Purpose] The purpose of this study was to determine effects of Gross Motor Function Classification System and Manual Ability Classification System levels on performance-based motor skills of children with spastic cerebral palsy. [Subjects and Methods] Twenty-three children with cerebral palsy were included. The Assessment of Motor and Process Skills was used to evaluate performance-based motor skills in daily life. Gross motor function was assessed using Gross Motor Function Classification S...

  13. Effects of gross motor function and manual function levels on performance-based ADL motor skills of children with spastic cerebral palsy.

    Science.gov (United States)

    Park, Myoung-Ok

    2017-02-01

    [Purpose] The purpose of this study was to determine effects of Gross Motor Function Classification System and Manual Ability Classification System levels on performance-based motor skills of children with spastic cerebral palsy. [Subjects and Methods] Twenty-three children with cerebral palsy were included. The Assessment of Motor and Process Skills was used to evaluate performance-based motor skills in daily life. Gross motor function was assessed using Gross Motor Function Classification Systems, and manual function was measured using the Manual Ability Classification System. [Results] Motor skills in daily activities were significantly different on Gross Motor Function Classification System level and Manual Ability Classification System level. According to the results of multiple regression analysis, children categorized as Gross Motor Function Classification System level III scored lower in terms of performance based motor skills than Gross Motor Function Classification System level I children. Also, when analyzed with respect to Manual Ability Classification System level, level II was lower than level I, and level III was lower than level II in terms of performance based motor skills. [Conclusion] The results of this study indicate that performance-based motor skills differ among children categorized based on Gross Motor Function Classification System and Manual Ability Classification System levels of cerebral palsy.

  14. Calibrating ADL-IADL scales to improve measurement accuracy and to extend the disability construct into the preclinical range: a systematic review

    Directory of Open Access Journals (Sweden)

    Starr John M

    2011-08-01

    Full Text Available Abstract Background Interest in measuring functional status among nondisabled older adults has increased in recent years. This is, in part, due to the notion that adults identified as 'high risk' for functional decline portray a state that is potentially easier to reverse than overt disability. Assessing relatively healthy older adults with traditional self-report measures (activities of daily living has proven difficult because these instruments were initially developed for institutionalised older adults. Perhaps less evident, are problems associated with change scores and the potential for 'construct under-representation', which reflects the exclusion of important features of the construct (e.g., disability. Furthermore, establishing a formal hierarchy of functional status tells more than the typical simple summation of functional loss, and may have predictive value to the clinician monitoring older adults: if the sequence task difficulty is accelerated or out of order it may indicate the need for interventions. Methods This review identified studies that employed item response theory (IRT to examine or revise functional status scales. IRT can be used to transform the ordinal nature of functional status scales to interval level data, which serves to increase diagnostic precision and sensitivity to clinical change. Furthermore, IRT can be used to rank items unequivocally along a hierarchy based on difficulty. It should be noted that this review is not concerned with contrasting IRT with more traditional classical test theory methodology. Results A systematic search of four databases (PubMed, Embase, CINAHL, and PsychInfo resulted in the review of 2,192 manuscripts. Of these manuscripts, twelve met our inclusion/exclusion requirements and thus were targeted for further inspection. Conclusions Manuscripts presented in this review appear to summarise gerontology's best efforts to improve construct validity and content validity (i.e., ceiling effects for scales measuring the early stages of activity restriction in community-dwelling older adults. Several scales in this review were exceptional at reducing ceiling effects, reducing gaps in coverage along the construct, as well as establishing a formal hierarchy of functional decline. These instrument modifications make it plausible to detect minor changes in difficulty for IADL items positioned at the edge of the disability continuum, which can be used to signal the onset of progressive type disability in older adults.

  15. Workplace and home smoking restrictions and racial/ethnic variation in the prevalence and intensity of current cigarette smoking among women by poverty status, TUS-CPS 1998-1999 and 2001-2002.

    Science.gov (United States)

    Shavers, Vickie L; Fagan, Pebbles; Alexander, Linda A Jouridine; Clayton, Richard; Doucet, Jennifer; Baezconde-Garbanati, Lourdes

    2006-09-01

    Recognition of the health consequences of exposure to environmental tobacco smoke has led government agencies and many employers to establish policies that restrict cigarette smoking in public and workplaces. This cross sectional study examines the association of workplace smoking policies and home smoking restrictions with current smoking among women. Participants were employed US women ages 18-64 who were self respondents to the 1998-1999 or 2000-2001 tobacco use supplement to the current population survey supplements. Cross tabulations and multivariate logistic regression analyses examine the association of selected demographic characteristics, occupation, income, workplace and home smoking policies/restrictions with current smoking, consumption patterns, and quit attempts among women by poverty level for five race/ethnic groups. The prevalence of either having an official workplace or home smoking policy that completely banned smoking increased with increased distance from the poverty level threshold. A complete ban on home smoking was more frequently reported by African American and Hispanic women although Hispanic women less frequently reported an official workplace smoking policy. In general, policies that permitted smoking in the work area or at home were associated with a higher prevalence of current smoking but this varied by poverty level and race/ethnicity. Home smoking policies that permitted smoking were associated with lower adjusted odds of having a least one quit attempt for nearly all poverty level categories but there was no association between having one quit attempt and workplace policies. Home smoking policies were more consistently associated with a lower prevalence of current smoking irrespective of poverty status or race/ethnicity than workplace policies. These findings underscore the importance of examining tobacco control policies in multiple domains (work and home) as well as by race/ethnicity and socioeconomic position.

  16. Modelo de gestão da tecnologia e do conhecimento para a integração de sistemas físico-cibernéticos (CPS aos processos logísticos das empresas

    Directory of Open Access Journals (Sweden)

    Diógenes Marcelo Cassiano Coriguazi

    2017-01-01

    Full Text Available The increasing needs for business efficiency improvement generates demands for new technologies. Such demands expand to logistics processes and the cyber-physical systems are the new trends to put these processes in a competitive level. For the implementation effectiveness of these new technologies it is need to develop a management model, for both technology and knowledge, looking for a lasting implementation, which can be disseminated through all corporation. The aim of this paper is to propose a technology and knowledge management model to support the integration of cyber-physical systems to the firms logistics processes. The proposed model aims to facilitate and speed up the cyber-physical systems integration to the firms logistics processes, such as material and information flows, by the technology and knowledge management, allowing the firms to monitor their performance improvement, sustaining a competitive advantage.

  17. Performance of activities of daily living among hospitalized cancer patients

    DEFF Research Database (Denmark)

    Lindahl-Jacobsen, Line; Hansen, Dorte Gilså; Wæhrens, Eva Ejlersen

    2015-01-01

    and characterize ADL task performance problems among a group of adult disabled hospitalized cancer patients using interview and questionnaire data. METHODS: Cross-sectional study on prevalence of ADL task performance problems experienced by disabled hospitalized cancer patients using the Activities of Daily Living...... Questionnaire (ADL-Q) (n = 118) and the Canadian Occupational Performance Measure (COPM) (n = 55). RESULTS: All 118 patients reported problems with ADL task performance. Based on the ADL-Q patients reported more problems within instrumental (I-)ADL than personal (P-)ADL. In both I-ADL and P-ADL the results......BACKGROUND: Many cancer patients report unmet rehabilitation needs. Rehabilitation may include activities of daily living (ADL) tasks, but little is known about how cancer patients perform these tasks and how they prioritize their daily activities. Hence, this study aims to identify...

  18. Albert Camus’nün Veba Adlı Romanında işlenen Esaret Duygusunun Algısal Açıdan Analizi

    OpenAIRE

    KAYA, Muzaffer; DEMİRAL, Serkan

    2013-01-01

    The Plague a novel by Albert Camus A sense of the state of being captured are reflected from different angles In the opus very different ways appear in a state of bondage and with a sense of where you are there are visible and invisible forms of bondage First the physical and physiological slavery and then the psychic and spiritual slavery Finally a time of heroes becomes routine status Even that cycle appears to be in danger of being a prisoner In general examining the whole o...

  19. Patrick Mccabe’in Plüton’da Kahvaltı ve Jeffrey Eugenides’in Middlesex adlı romanlarında cinsel kimlik, aile ve göç

    OpenAIRE

    DEMİR, Elif

    2016-01-01

    Cinsiyet  ve  toplumsal  cinsiyet  kavramları  merak  ve  ilham  uyandıran  yapısıyla  pek  çok  bilimsel  alanın  ilgi  konusu  olmuş  ve  kadın/erkek  ikiliği  dışına  çıkan  bireylere  atfedilen  ‘queer’  kavramıyla  edebi  imgelemde &nbs...

  20. XVI. Yüzyıl Türkiyesi’nde Ahi Adlı Zaviyelerin Dağılışı The Distrubution Of Akhi Lodges in XVI. Century Turkey

    Directory of Open Access Journals (Sweden)

    İlker YİĞİT

    2013-07-01

    Full Text Available Akhism, is an organization which has political, social andeconomic aspects, has been encountered the traces since XIII. Centuryin Turkey. Akhism has quite different perspectives (in terms of itsorigin, its socio-economic and social impacts, etc. and has subjected toseveral studies. Akhism may be perceived as an artisan organization,however; it is an important organization that has undertaken crucialactive roles in such as the execution of Turkization of Anatolia, openingsettlements from the desolate places and establishment of newresidential units. Indeed, (Ahi's settlements provide evidence for thissituation in XVI. century,especially by giving their names toneighbourhoods in urban areas; and to the villages, hamlets, farmsand uplands in rural areas. Akhi lodges are the venues in which theAkhi maintain their effectiveness in rural and urban areas. The Akhidervish lodges, the social organization (association created by thetradesmen and artisans together in order to provide mystical solidaritybetween the members of that culture, are the establishment which givedirections to social and economic life in the erea. The Akhi dervishlodges are one of the cultural centers in terms of both offering a widetraining services where there is no madrasa instiutution and alsohosting shelters where people come from outsides of villages or cities.The Akhi lodges provide the formation of inhabited by having animportant role in the establishment and development of the settlementsin cities and rural areas. Therefore, this study includes Akhism lodges,which have conducted their effectiveness in both urban and rural areas,and covers the distribution of XVI. century Turkey Akhism lodges.Akhi lodges, which can be encountered in almost every part of Anatolia,are deeply affecting institutions with their activities and events, haveundertaken active roles in that period of social, political and economiclife of Anatolia since Turkization of Anatolia. It is quite crucial in termsof revealing their missions as being more intense of Zaviye (lodgesnamed Akhi in the areas considered as "end zones" than other areasduring Turkization of Anatolia.

  1. Sahîh Adlı Eseri Çerçevesinde İBN HİBBN'IN TEFSİR ANLAYIŞINA DAİR TESPİTLER

    Directory of Open Access Journals (Sweden)

    Eyüp YAKA

    2008-06-01

    Full Text Available Some Determinations about Ibn Hibban's Exegetic Conception within The Framework of His Book of SahihIn this study, I tried to make some determinations on Ibn Hibban's exegetic conception in the framework of his monumental work Sahih which is on the science of Hadith. The author had tried much to understand hadiths. He tried to expose the meanings of hadith which are seen as contradictory with the rational and logical interpretations and some times with some verses. Ibn Hibban had tried also to interpret some verses which are mentioned in his work. Through the examination of his methods we can be able to reach some remarks regarding his exegetic conception.Ibn Hibban added to his book the reports related to the sabab an-nuzûl and the Prophet's explanations of verses but he never commented on them. This indicates to his eager of giving much importance to reports and sunnah in interpreting the verses.His comments on the understanding the verses have been scrutinized under an independent sub-title. He studied numerous verses in a multi-dimensional way concerning the words lexicon meaning and Arabic linguistical style. Moreover, he referred to the methods of interpreting the verses with verses and sunnah.Ibn Hibban, has tried to interpret the verses related to the separate subjects such as relation between the Prophet and his companions, fitrat, sifat Allah, ru'yat Allah, Muslim and non-Muslim relations. He also tried to interpret some verses which have legal content of Qur'ân. Consequently, although in his exegetic conception the method of report (riwayat is dominant but he also refered to the method of dirayat.

  2. Towards Service-Oriented Middleware for Fog and Cloud Integrated Cyber Physical Systems

    DEFF Research Database (Denmark)

    Mohamed, Nader; Lazarova-Molnar, Sanja; Jawhar, Imad

    2017-01-01

    enables the integration of CPS with other systems such as Cloud and Fog Computing. Furthermore, as CPS can be developed for various applications at different scales, this paper provides a classification for CPS applications and discusses how CPSWare can effectively deal with the different issues in each...... of the applications. An appropriate middleware is needed to provide infrastructural support and assist the development and operations of diverse CPS applications. This paper studies utilizing the service-oriented middleware (SOM) approach for CPS and discusses the advantages and requirements for such utilization....... In addition, it proposes an SOM for CPS, called CPSWare. This middleware views all CPS components as a set of services and provides a service-based infrastructure to develop and operate CPS applications. This approach provides systemic solutions for solving many computing and networking issues in CPS. It also...

  3. Features of Computerized Procedure System of Shin-Kori unit 5 and 6

    International Nuclear Information System (INIS)

    Seong, Nokyu; Jung, Yeonsub; Sung, Chanho

    2016-01-01

    The Computerized Procedure System (CPS) is one of the Man Machine Interface (MMI) resources of Main Control Room (MCR) of the Advanced Power Reactor 1400 (APR1400). The CPS has been continuously improved since it was installed in Shin-Kori unit 3 and 4. The Korea Hydro Nuclear Power Central Research Institute (KHNP CRI) has found the points of improvement of CPS through CPS centered Human Factors Engineering Verification and Validation (HFE V and V) and Operating Experience Review (OER) of reference power plant. This paper shows the main features of CPS of Shin-Kori 5 and 6 unit. This paper shows the main features of CPS of Shin-Kori 5 and 6. These are some of improvements of CPS. This prototype of CPS currently is implementing in CRI. The respective function can be more detailed after testing the prototype. These features will be applied to Shin-Kori 5 and 6 CPS after HFE V and V

  4. Features of Computerized Procedure System of Shin-Kori unit 5 and 6

    Energy Technology Data Exchange (ETDEWEB)

    Seong, Nokyu; Jung, Yeonsub; Sung, Chanho [KHNP CRI, Daejeon (Korea, Republic of)

    2016-10-15

    The Computerized Procedure System (CPS) is one of the Man Machine Interface (MMI) resources of Main Control Room (MCR) of the Advanced Power Reactor 1400 (APR1400). The CPS has been continuously improved since it was installed in Shin-Kori unit 3 and 4. The Korea Hydro Nuclear Power Central Research Institute (KHNP CRI) has found the points of improvement of CPS through CPS centered Human Factors Engineering Verification and Validation (HFE V and V) and Operating Experience Review (OER) of reference power plant. This paper shows the main features of CPS of Shin-Kori 5 and 6 unit. This paper shows the main features of CPS of Shin-Kori 5 and 6. These are some of improvements of CPS. This prototype of CPS currently is implementing in CRI. The respective function can be more detailed after testing the prototype. These features will be applied to Shin-Kori 5 and 6 CPS after HFE V and V.

  5. 76 FR 50224 - Medicare Program; Accountable Care Organization Accelerated Development Learning Sessions; Center...

    Science.gov (United States)

    2011-08-12

    ...] Medicare Program; Accountable Care Organization Accelerated Development Learning Sessions; Center for... (CMS). This two-day training session is the second Accelerated Development Learning Session (ADLS.... Through Accelerated Development Learning Sessions (ADLS), the Innovation Center will test whether...

  6. Toward real time detection of the basic living activity in home using a wearable sensor and smart home sensors.

    Science.gov (United States)

    Bang, Sunlee; Kim, Minho; Song, Sa-Kwang; Park, Soo-Jun

    2008-01-01

    As the elderly people living alone are enormously increasing recently, we need the system inferring activities of daily living (ADL) for maintaining healthy life and recognizing emergency. The system should be constructed with sensors, which are used to associate with people's living while remaining as non intrusive views as possible. To do this, the proposed system use a triaxial accelerometer sensor and environment sensors indicating contact with subject in home. Particularly, in order to robustly infer ADLs, we present component ADL, which is decided with conjunction of human motion together, not just only contacted object identification. It is an important component in inferring ADL. In special, component ADL decision firstly refines misclassified initial activities, which improves the accuracy of recognizing ADL. Preliminary experiments results for proposed system provides overall recognition rate of over 97% over 8 component ADLs, which can be effectively applicable to recognize the final ADLs.

  7. The Hamlet Application Design Language: introductory definition report

    NARCIS (Netherlands)

    M.R. van Steen

    1993-01-01

    textabstractThis report provides an introduction to the definition of the Hamlet Application Design Language (ADL). ADL is a graphical-based language and notation supporting the design of parallel real-time applications. Designs expressed in ADL are based on a model of processes that communicate by

  8. Impact of 4 Lactobacillus plantarum capsular polysaccharide clusters on surface glycan composition and host cell signaling

    Directory of Open Access Journals (Sweden)

    Remus Daniela M

    2012-11-01

    Full Text Available Abstract Background Bacterial cell surface-associated polysaccharides are involved in the interactions of bacteria with their environment and play an important role in the communication between pathogenic bacteria and their host organisms. Cell surface polysaccharides of probiotic species are far less well described. Therefore, improved knowledge on these molecules is potentially of great importance to understand the strain-specific and proposed beneficial modes of probiotic action. Results The Lactobacillus plantarum WCFS1 genome encodes 4 clusters of genes that are associated with surface polysaccharide production. Two of these clusters appear to encode all functions required for capsular polysaccharide formation (cps2A-J and cps4A-J, while the remaining clusters are predicted to lack genes encoding chain-length control functions and a priming glycosyl-transferase (cps1A-I and cps3A-J. We constructed L. plantarum WCFS1 gene deletion mutants that lack individual (Δcps1A-I, Δcps2A-J, Δcps3A-J and Δcps4A-J or combinations of cps clusters (Δcps1A-3J and Δcps1A-3I, Δcps4A-J and assessed the genome wide impact of these mutations by transcriptome analysis. The cps cluster deletions influenced the expression of variable gene sets in the individual cps cluster mutants, but also considerable numbers of up- and down-regulated genes were shared between mutants in cps cluster 1 and 2, as well as between mutant in cps clusters 3 and 4. Additionally, the composition of overall cell surface polysaccharide fractions was altered in each mutant strain, implying that despite the apparent incompleteness of cps1A-I and cps3A-J, all clusters are active and functional in L. plantarum. The Δcps1A-I strain produced surface polysaccharides in equal amounts as compared to the wild-type strain, while the polysaccharides were characterized by a reduced molar mass and the lack of rhamnose. The mutants that lacked functional copies of cps2A-J, cps3A-J or cps4A

  9. Customer premises services market demand assessment 1980 - 2000: Volume 2

    Science.gov (United States)

    Gamble, R. B.; Saporta, L.; Heidenrich, G. A.

    1983-01-01

    Potential customer premises service (CPS), telecommunication services, potential CPS user classes, a primary research survey, comparative economics, market demand forcasts, distance distribution of traffic, segmentation of market demand, and a nationwide traffic distribution model are discussed.

  10. Ability to perform Actvities of Daily Living among patients with bipolar disorder in remission

    DEFF Research Database (Denmark)

    Decker, Lone; Träger, Conny; Miskowiak, Kamilla

    2017-01-01

    in the community. While participants reported decreased ADL ability, especially within instrumental ADL, they had a tendency towards evaluating themselves as more competent than what was observed. No relationships between measures of observed and self-reported ADL ability were found. Conclusion: Overall, patients......ABSTRACT Aims: Patients with bipolar disorder often experience disability in terms of cognitive impairments and activity limitations even in remission. However, knowledge is sparse concerning the ability to perform Activities of Daily Living (ADL) during remission. The aim of this study was to (1......) investigate the observed and self-reported ability to perform ADL tasks and (2) examine the association between observed and self-reported ability to perform ADL in patients with bipolar disorder in remission. Methods: The observed ADL ability was assessed with the Assessment of Motor and Process Skills...

  11. A Longitudinal Study of Changes in Asylum Seekers Ability Regarding Activities of Daily Living During Their Stay in the Asylum Center

    DEFF Research Database (Denmark)

    Morville, Anne-Le; Amris, Kirstine; Eklund, Mona

    2015-01-01

    participated. ADL-ability was measured using Assessment of Motor and Process Skills and questionnaires about exposure to torture, self-reported mental health and pain. ADL motor and process measures, well-being and self-rated health declined from baseline to follow-up. Measures of pain and depression increased......The aim was to assess change in activities of daily living (ADL) ability amongst asylum seekers and if there were any difference between tortured and non-torture following a 10 months post-arrival period, and if self-reported health and exposure to torture were factors related to change in ADL....... Exposure to physical torture and change in ADL motor (r = 0.525) measures were associated, as well as change in current pain and change in ADL process (r = 0.525) measures. Due to preponderance of torture survivors analysis of group difference was not applicable. Health care workers should be aware of ADL...

  12. Linking Complex Problem Solving and General Mental Ability to Career Advancement: Does a Transversal Skill Reveal Incremental Predictive Validity?

    Science.gov (United States)

    Mainert, Jakob; Kretzschmar, André; Neubert, Jonas C.; Greiff, Samuel

    2015-01-01

    Transversal skills, such as complex problem solving (CPS) are viewed as central twenty-first-century skills. Recent empirical findings have already supported the importance of CPS for early academic advancement. We wanted to determine whether CPS could also contribute to the understanding of career advancement later in life. Towards this end, we…

  13. Agent-Based Modeling of Collaborative Problem Solving. Research Report. ETS RR-16-27

    Science.gov (United States)

    Bergner, Yoav; Andrews, Jessica J.; Zhu, Mengxiao; Gonzales, Joseph E.

    2016-01-01

    Collaborative problem solving (CPS) is a critical competency in a variety of contexts, including the workplace, school, and home. However, only recently have assessment and curriculum reformers begun to focus to a greater extent on the acquisition and development of CPS skill. One of the major challenges in psychometric modeling of CPS is…

  14. The Process of Solving Complex Problems

    Science.gov (United States)

    Fischer, Andreas; Greiff, Samuel; Funke, Joachim

    2012-01-01

    This article is about Complex Problem Solving (CPS), its history in a variety of research domains (e.g., human problem solving, expertise, decision making, and intelligence), a formal definition and a process theory of CPS applicable to the interdisciplinary field. CPS is portrayed as (a) knowledge acquisition and (b) knowledge application…

  15. [Development of an activity of daily living scale for patients with COPD: the Activity of Daily Living Dyspnea scale].

    Science.gov (United States)

    Yoza, Yoshiyasu; Ariyoshi, Koya; Honda, Sumihisa; Taniguchi, Hiroyuki; Senjyu, Hideaki

    2009-10-01

    Patients with COPD often experience restriction in their activities of daily living (ADL) due to dyspnea. This type of restriction is unique to patients with COPD and cannot be adequately evaluated by the generic ADL scales. This study developed an ADL scale (the Activity of Daily Living Dyspnea scale [ADL-D scale]) for patients with COPD and investigated its validity and internal consistency. Patients with stable COPD were recruited and completed a pilot 26-item questionnaire. Patients also performed the Incremental Shuttle Walk Test (ISWT), and completed the St George's Respiratory Questionnaire (SGRQ), and Medical Research Council (MRC) dyspnea grade. There were 83 male participants who completed the pilot questionnaire. Following the pilot, 8 items that were not undertaken by the majority of subjects, and 3 items judged to be of low clinical importance by physical therapists were removed from the pilot questionnaire. The final ADL-D scale contained 15 items. Scores obtained with the ADL-D scale were significantly correlated with the MRC dyspnea grades, distance walked on the ISWT and SGRQ scores. The ADL-D scores were significantly different across the five grades of the MRC dyspnea grade. The ADL-D scale showed high consistency (Chronbach's alpha coefficient of 0.96). The ADL-D scale is a useful scale for assessing impairments in ADL in Japanese male patients with COPD.

  16. EFFECT OF SUBSTITUTION POSITION OF HYDROXY GROUP AT BENZOIC ACID ON THE LUMINESCENT AND DEGRADATION PROPERTIES OF POLY[DI(CARBOXYPHENYL) SUCCINATE-co-SEBACIC ANHYDRIDE]S

    Institute of Scientific and Technical Information of China (English)

    Jun Fan; Hong-liang Jiang; Kang-jie Zhu

    2007-01-01

    In this work, two new diacids, di(m-carboxyphenyl) succinate (m-dCPS) and di(o-carboxyphenyl) succinate (o-dCPS), were synthesized by reaction of m-, o-hydroxy benzoic acid with succinic chloride, respectively. Their corresponding copolymers with sebacic acid (SA), P(m-dCPS:SA) and P(o-dCPS:SA), were prepared by melt copolycondensation and characterized by NMR, UV and DSC methods. Compared with inherently fluorescent poly[di(p-carboxyphenyl) succinateco-sebacic anhydride] (P(p-dCPS:SA)), P(m-dCPS:SA) and P(o-dCPS:SA) displayed different luminescent properties. P(m-dCPS:SA) could emit fluorescence under the excitation of both visible and UV light, while P(o-dCPS:SA) could only emit fluorescence when excited with UV light. Degradation rate of the two new copolyanhydrides increased with the increase of SA fraction in the copolymers. In addition, P(o-dCPS:SA) degraded more rapidly than P(m-dCPS:SA) with the same composition. Typical surface-degradation characteristics of these copolyanhydrides were observed.

  17. Mobile Computerized Procedure System for the Improved Situation Awareness among Field Workers and Main Control Room Operators

    International Nuclear Information System (INIS)

    Lee, Sungjin; Seong, Nokyu; Jung, Yeonsub

    2013-01-01

    This paper explains the technical issues of the mobile CPS (m-CPS) in the conceptual development stage. The proposed m-CPS can be developed with many recent technologies in the various industry fields based on CRI CPS. Performance and stability of CRI CPS have been tested several times until now. It is expected that more human errors can be reduced by the m-CPS through improved situation awareness and human performance tools for local workers and MCR operators. Some considerations as well as mentioned ones will be reflected in the m-CPS development. Human errors can occur during the test and maintenance of the generator, safety injection system and reactor coolant inventory in nuclear power plants (NPPs). Most of human errors have been occurred by the omission of the prevention techniques such as the self-check, the peer-check, the concurrent verification and etc. Another important reason is the insufficient information sharing among main control room (MCR) operators and field workers. Various field service automation tools have been developed with recent information technology in many countries. APR1400 computerized procedure system (CPS) has been developed for the MCR operators of Shin-Kori 3 and 4 units. Especially, the concurrent verification support design is applied in the construction project of Shin-Hanul 1 and 2 CPS. KHNP central research institute (CRI) expects that the extended application of CPS including the field activity, that is a kind of mobile CPS, can enhance the reduction of human errors

  18. William Wordsworth's 'Double Awareness' of Memory in Virginia Woolf's Mrs Dalloway = William Wordsworth'un 'Hatıranın Çift Yönlü Algılaması' Kavramının Virgina Woolf'un Mrs Dalloway Adlı Romanındaki Kullanımı

    Directory of Open Access Journals (Sweden)

    Ali GÜNEŞ

    2003-06-01

    Full Text Available This article deals with Romanticism in modernist British writer Virginia Woolf's novel, Mrs Dalloway. Although her works are experimental and new, they are part of a wider and developing perspective in the historical process of literary tradition, so that they cannot be viewed as completely breaking away from literary tradition, but rather as a reworking and redevelopment in its evolution. In her reworking of the traditional novel, this paper may suggest that Woolf made it "new" by returning to the Romantics, particularly to Wordsworth. By this claim, this paper does not mean that Woolf copied Wordsworth exactly, but was profoundly and pervasively influenced by his aesthetic views, especially in relation to her understanding of life as "consciousness". By returning to the Romantics, Woolf develops her sense of "reality" as both fragmented and whole, and of the "self" as fragmented but desiring and imagining unity. Hence she not only strove to construct a poetical or lyrical novel to express that contradictory view but also used her fiction to explore the mystery of the subjective consciousness as the dominant modernist view. In order to express her perception of modernist identity, Woolf used memory as a device in Mrs Dalloway and thus developed a new way of narration as well as a new view of human identity. By means of this new method, she left the objective narration of the traditional novel, and thus meaning or the view of identity in Woolf's late fiction is not static but undecided, unfinished and mysterious.

  19. Metindilbilimi Metindilbilimsel Bağdaşıklık ve Haldun Taner’in Onikiye Bir Var Adlı Öyküsünde Metindilbilimsel Bağdaşıklık Görünümleri

    OpenAIRE

    ÖZKAN, Bülent

    2013-01-01

    This article is a comprehensive summary of the seminar study whose name is “Text Linguistics And Text Linguistics Cohesion At The Story ‘Onikiye Bir Var’ by Haldun TANER” In this article we aimed to research what ‘text linguistics’ and ‘text linguistic chosion’ are and how the text linguistic chosion is reflected in the story ‘Onikiye Bir Var’ by Haldun TANER Key words: Text Linguistics Text Linguistics Cohesion Haldun TANER

  20. Study of the noncylindrical Z-pinch during discharges in neon using electro-optical transducer of the AGAT type

    International Nuclear Information System (INIS)

    Lebedev, V.B.; Orlov, M.M.; Saulevich, S.V.; Terent'ev, A.R.; Khrabrov, V.A.

    1986-01-01

    Results of investigation into running away current-plasma sheath (CPS) of noncylindrical Z-pinch are given. Experimental chamber was filled with neon up to 3 torr pressure. Store of energy was equal to 20 kJ. CPS radiation spectrum scanning was recorded in the phase of its convergence to the system axis by means of an electron-optical converter of the AGAT type. Electron temperature in the inflection region on CPS constituted 3 eV. Possibilities of magnetic field diffusion through neon CPS and appearance of CPS running away mode are shown. CPS plasma spectra indicated that radiation can be recorded only from a CPS head near-anode part and its external peripheral regions moving from the axis and emitting considerably less quantity of radiation

  1. Complex Problems in Entrepreneurship Education: Examining Complex Problem-Solving in the Application of Opportunity Identification

    Directory of Open Access Journals (Sweden)

    Yvette Baggen

    2017-01-01

    Full Text Available In opening up the black box of what entrepreneurship education (EE should be about, this study focuses on the exploration of relationships between two constructs: opportunity identification (OI and complex problem-solving (CPS. OI, as a domain-specific capability, is at the core of entrepreneurship research, whereas CPS is a more domain-general skill. On a conceptual level, there are reasons to believe that CPS skills can help individuals to identify potential opportunities in dynamic and nontransparent environments. Therefore, we empirically investigated whether CPS relates to OI among 113 masters students. Data is analyzed using multiple regressions. The results show that CPS predicts the number of concrete ideas that students generate, suggesting that having CPS skills supports the generation of detailed, potential business ideas of good quality. The results of the current study suggest that training CPS, as a more domain-general skill, could be a valuable part of what should be taught in EE.

  2. Cross-national comparisons of complex problem-solving strategies in two microworlds.

    Science.gov (United States)

    Güss, C Dominik; Tuason, Ma Teresa; Gerhard, Christiane

    2010-04-01

    Research in the fields of complex problem solving (CPS) and dynamic decision making using microworlds has been mainly conducted in Western industrialized countries. This study analyzes the CPS process by investigating thinking-aloud protocols in five countries. Participants were 511 students from Brazil, Germany, India, the Philippines, and the United States who worked on two microworlds. On the basis of cultural-psychological theories, specific cross-national differences in CPS strategies were hypothesized. Following theories of situatedness of cognition, hypotheses about the specific frequency of problem-solving strategies in the two microworlds were developed. Results of the verbal protocols showed (a) modification of the theoretical CPS model, (b) task dependence of CPS strategies, and (c) cross-national differences in CPS strategies. Participants' CPS processes were particularly influenced by country-specific problem-solving strategies. Copyright © 2009 Cognitive Science Society, Inc.

  3. Security analysis of cyber-physical system

    Science.gov (United States)

    Li, Bo; Zhang, Lichen

    2017-05-01

    In recent years, Cyber-Physical System (CPS) has become an important research direction of academic circles and scientific and technological circles at home and abroad, is considered to be following the third wave of world information technology after the computer, the Internet. PS is a multi-dimensional, heterogeneous, deep integration of open systems, Involving the computer, communication, control and other disciplines of knowledge. As the various disciplines in the research theory and methods are significantly different, so the application of CPS has brought great challenges. This paper introduces the definition and characteristics of CPS, analyzes the current situation of CPS, analyzes the security threats faced by CPS, and gives the security solution for security threats. It also discusses CPS-specific security technology, to promote the healthy development of CPS in information security.

  4. The toxic effects of chlorophenols and associated mechanisms in fish

    International Nuclear Information System (INIS)

    Ge, Tingting; Han, Jiangyuan; Qi, Yongmei; Gu, Xueyan; Ma, Lin; Zhang, Chen; Naeem, Sajid; Huang, Dejun

    2017-01-01

    Highlights: • We review the toxic effects of chlorophenols (CPs) and underlying mechanisms in fish. • CPs induce lethal effects, oxidative stress, endocrine disruption, reproductive toxicity and apoptosis in fish. • CPs exhibit toxicity through multiple signaling pathways in fish and different pathways co-exist under the same conditions. • Studies on DNA methylation provide new insights into our understanding of epigenetic mechanisms of CPs-induced toxicity. • Mechanisms studies on CPs toxicity performed under environmental concentrations need more attentions. - Abstract: Chlorophenols (CPs) are ubiquitous contaminants in the environment primarily released from agricultural and industrial wastewater. These compounds are not readily degraded naturally, and easily accumulate in organs, tissues and cells via food chains, further leading to acute and chronic toxic effects on aquatic organisms. Herein, we review the available literature regarding CP toxicity in fish, with special emphasis on the potential toxic mechanisms. CPs cause oxidative stress via generation of reactive oxygen species, induction of lipid peroxidation and/or oxidative DNA damage along with inhibition of antioxidant systems. CPs affect immune system by altering the number of mature B cells and macrophages, while suppressing phagocytosis and down-regulating the expression of immune factors. CPs also disrupt endocrine function by affecting hormone levels, or inducing abnormal gene expression and interference with hormone receptors. CPs at relatively higher concentrations induce apoptosis via mitochondria-mediated pathway, cell death receptor-mediated pathway, and/or DNA damage-mediated pathway. CPs at relatively lower concentrations promote cell proliferation, and foster cancers-prone environment by increasing the rate of point mutations and oxidative DNA lesions. These toxic effects in fish are induced directly by CPs per se or indirectly by their metabolic products. In addition, recent

  5. The toxic effects of chlorophenols and associated mechanisms in fish

    Energy Technology Data Exchange (ETDEWEB)

    Ge, Tingting; Han, Jiangyuan; Qi, Yongmei; Gu, Xueyan; Ma, Lin; Zhang, Chen; Naeem, Sajid; Huang, Dejun, E-mail: huangdj@lzu.edu.cn

    2017-03-15

    Highlights: • We review the toxic effects of chlorophenols (CPs) and underlying mechanisms in fish. • CPs induce lethal effects, oxidative stress, endocrine disruption, reproductive toxicity and apoptosis in fish. • CPs exhibit toxicity through multiple signaling pathways in fish and different pathways co-exist under the same conditions. • Studies on DNA methylation provide new insights into our understanding of epigenetic mechanisms of CPs-induced toxicity. • Mechanisms studies on CPs toxicity performed under environmental concentrations need more attentions. - Abstract: Chlorophenols (CPs) are ubiquitous contaminants in the environment primarily released from agricultural and industrial wastewater. These compounds are not readily degraded naturally, and easily accumulate in organs, tissues and cells via food chains, further leading to acute and chronic toxic effects on aquatic organisms. Herein, we review the available literature regarding CP toxicity in fish, with special emphasis on the potential toxic mechanisms. CPs cause oxidative stress via generation of reactive oxygen species, induction of lipid peroxidation and/or oxidative DNA damage along with inhibition of antioxidant systems. CPs affect immune system by altering the number of mature B cells and macrophages, while suppressing phagocytosis and down-regulating the expression of immune factors. CPs also disrupt endocrine function by affecting hormone levels, or inducing abnormal gene expression and interference with hormone receptors. CPs at relatively higher concentrations induce apoptosis via mitochondria-mediated pathway, cell death receptor-mediated pathway, and/or DNA damage-mediated pathway. CPs at relatively lower concentrations promote cell proliferation, and foster cancers-prone environment by increasing the rate of point mutations and oxidative DNA lesions. These toxic effects in fish are induced directly by CPs per se or indirectly by their metabolic products. In addition, recent

  6. Occupational therapy evaluation

    DEFF Research Database (Denmark)

    Nielsen, Kristina Tomra; Wæhrens, Eva Ejlersen

    2015-01-01

    performance based on self-report and observation, respectively, and to examine the relationship between measures of self-reported and observed quality of ADL task performance. Methods: The quality of ADL task performance among 20 adults with depression was evaluated using the ADL Interview (ADL......-I) and the Assessment of Motor and Process Skills (AMPS). Results and conclusions: Results indicated that participants both reported and demonstrated increased effort and/or fatigue, increased use of time, need for assistance, and safety problems. However, little relationship was found between measures of self......-reported and observed quality of ADL task performance, supporting the use of both self-report and observation as part of the evaluation phase outlined in the OTIPM. Key words: activities of daily living, depression, assessment, interview, OTIPM, ADL-I, AMPS...

  7. Early prediction of outcome of activities of daily living after stroke: a systematic review

    OpenAIRE

    Veerbeek, J.M.; Kwakkel, G.; Wegen, van, E.E.H.; Ket, J.C.F.; Heijmans, M.W.

    2011-01-01

    BACKGROUND AND PURPOSE-Knowledge about robust and unbiased factors that predict outcome of activities of daily living (ADL) is paramount in stroke management. This review investigates the methodological quality of prognostic studies in the early poststroke phase for final ADL to identify variables that are predictive or not predictive for outcome of ADL after stroke. METHODS-PubMed, Ebsco/Cinahl and Embase were systematically searched for prognostic studies in which stroke patients were inclu...

  8. Rehabilitation of limb apraxia improves daily life activities in patients with stroke.

    Science.gov (United States)

    Smania, N; Aglioti, S M; Girardi, F; Tinazzi, M; Fiaschi, A; Cosentino, A; Corato, E

    2006-12-12

    We randomly assigned 33 patients with left hemisphere stroke, limb apraxia, and aphasia to an apraxia or a control (aphasia) treatment group. Before and after each treatment, patients underwent a comprehensive neuropsychological testing battery and a caregiver evaluation of patient's activities of daily life (ADL) independence. Apraxia severity was related with ADL independence. Control (aphasia) treatment improved patients' language and intelligence performance. Apraxia treatment specifically improved praxic function and ADL.

  9. The influence of exercise intervention upon quality of life and activity of daily living in elderly people who use nursing care insurance services

    OpenAIRE

    竹内, 亮

    2012-01-01

    The purpose of this study was to confirm the importance of enhancing quality of life (QOL) and activity of daily living (ADL) in elderly people, and to examine methods of exercise intervention for QOL and ADL outcomes in elderly people who use nursing care insurance services. Chapter 2 clarifies the relationship between QOL, ADL, and changes in the level of independence in elderly residents. Higher QOL outcomes (sense of well-being, satisfaction with social support, independence, and beh...

  10. Functional capacity and dependency in transfer and dressing are associated with depressive symptoms in older people.

    Science.gov (United States)

    Boström, Gustaf; Conradsson, Mia; Rosendahl, Erik; Nordström, Peter; Gustafson, Yngve; Littbrand, Håkan

    2014-01-01

    This study examined associations between depressive symptoms and functional capacity, overall dependency in personal activities of daily living (ADLs), and dependency in individual ADL tasks, respectively, in people with a high mean age, large range of functional capacity, and wide spectrum of dependency in ADLs. Cross-sectional data from three studies were used. A total of 392 individuals living in community and residential care facilities were included. Mean age was 86.2 years, 72% were women, 75% were dependent in ADLs, 42% had depression, and 39% had dementia. Depressive symptoms were assessed with the 15-item Geriatric Depression Scale (GDS-15), functional capacity with the Berg Balance Scale (BBS), and ADLs with the Barthel ADL Index. Multiple linear regression analyses with comprehensive adjustments were performed between GDS-15 and BBS, GDS-15 and Barthel ADL Index, and GDS-15 and each individual ADL task, separately. GDS-15 score was associated with BBS score (unstandardized b =-0.03, P=0.008), but not with Barthel ADL Index score (unstandardized b =-0.07, P=0.068). No significant interaction effects of sex, dementia, or living conditions were found in these associations. Among individual ADL tasks, dependency in transfer (unstandardized b =-1.03, P=0.007) and dressing (unstandardized b =-0.70, P=0.035) were associated with depressive symptoms. Functional capacity seems to be independently associated with depressive symptoms in older people living in community and residential care facilities, whereas overall ADL performance may not be associated. Dependency in the individual ADL tasks of transfer and dressing appear to be independently associated with depressive symptoms and may be an important focus of future interdisciplinary multifactorial intervention studies.

  11. The integration of information and communication technology into community pharmacists practice in Barcelona.

    Science.gov (United States)

    Lupiáñez-Villanueva, Francisco; Hardey, Michael; Lluch, Maria

    2014-03-01

    The study aims to identify community pharmacists' (CPs) utilization of information and communication technology (ICT); to develop and characterize a typology of CPs' utilization of ICT and to identify factors that can enhance or inhibit the use of these technologies. An online survey of the 7649 members of the Pharmacist Association of Barcelona who had a registered email account in 2006 was carried out. Factor analysis, cluster analysis and binomial logit modelling were undertaken. Multivariate analysis of the CPs' responses to the survey (648) revealed two profiles of adoption of ICT. The first profile (40.75%) represents those CPs who place high emphasis on ICT within their practice. This group is therefore referred to as 'integrated CPs'. The second profile (59.25%) represents those CPs who make less use of ICT and so are consequently labelled 'non-integrated CPs'. Statistical modelling was used to identify variables that were important in predisposing CPs to integrate ICT with their work. From the analysis it is evident that responses to questions relating to 'recommend patients going on line for health information'; 'patients discuss or share their Internet health information findings'; 'emphasis on the Internet for communication and dissemination' and 'Pharmacists Professional Association information' play a positive and significant role in the probability of being an 'integrated CP'. The integration of ICT within CPs' practices cannot be adequately understood and appreciated without examining how CPs are making use of ICT within their own practice, their organizational context and the nature of the pharmacists-client relationship.

  12. Organization of the capsule biosynthesis gene locus of the oral streptococcus Streptococcus anginosus.

    Science.gov (United States)

    Tsunashima, Hiroyuki; Miyake, Katsuhide; Motono, Makoto; Iijima, Shinji

    2012-03-01

    The capsular polysaccharide (CPS) of the important oral streptococcus Streptococcus anginosus, which causes endocarditis, and the genes for its synthesis have not been clarified. In this study, we investigated the gene locus required for CPS synthesis in S. anginosus. Southern hybridization using the cpsE gene of the well-characterized bacterium S. agalactiae revealed that there is a similar gene in the genome of S. anginosus. By using the colony hybridization technique and inverse PCR, we isolated the CPS synthesis (cps) genes of S. anginosus. This gene cluster consisted of genes containing typical regulatory genes, cpsA-D, and glycosyltransferase genes coding for glucose, rhamnose, N-acetylgalactosamine, and galactofuranose transferases. Furthermore, we confirmed that the cps locus is required for CPS synthesis using a mutant strain with a defective cpsE gene. The cps cluster was found to be located downstream the nrdG gene, which encodes ribonucleoside triphosphate reductase activator, as is the case in other oral streptococci such as S. gordonii and S. sanguinis. However, the location of the gene cluster was different from those of S. pneumonia and S. agalactiae. Copyright © 2011 The Society for Biotechnology, Japan. Published by Elsevier B.V. All rights reserved.

  13. Effects of impairment in activities of daily living on predicting mortality following hip fracture surgery in studies using administrative healthcare databases

    Science.gov (United States)

    2014-01-01

    Background Impairment in activities of daily living (ADL) is an important predictor of outcomes although many administrative databases lack information on ADL function. We evaluated the impact of ADL function on predicting postoperative mortality among older adults with hip fractures in Ontario, Canada. Methods Sociodemographic and medical correlates of ADL impairment were first identified in a population of older adults with hip fractures who had ADL information available prior to hip fracture. A logistic regression model was developed to predict 360-day postoperative mortality and the predictive ability of this model were compared when ADL impairment was included or omitted from the model. Results The study sample (N = 1,329) had a mean age of 85.2 years, were 72.8% female and the majority resided in long-term care (78.5%). Overall, 36.4% of individuals died within 360 days of surgery. After controlling for age, sex, medical comorbidity and medical conditions correlated with ADL impairment, addition of ADL measures improved the logistic regression model for predicting 360 day mortality (AIC = 1706.9 vs. 1695.0; c -statistic = 0.65 vs 0.67; difference in - 2 log likelihood ratios: χ2 = 16.9, p = 0.002). Conclusions Direct measures of ADL impairment provides additional prognostic information on mortality for older adults with hip fractures even after controlling for medical comorbidity. Observational studies using administrative databases without measures of ADLs may be potentially prone to confounding and bias and case-mix adjustment for hip fracture outcomes should include ADL measures where these are available. PMID:24472282

  14. Application of computerized procedure system for AP1000

    International Nuclear Information System (INIS)

    Wen Fang

    2012-01-01

    With the tendency of digitalisation in instrumentation and control system of nuclear power plants, AP1000, as well as other advanced PWRs, is provided with the technical basis for the application of CPS (computerized procedure system). This paper makes a brief introduction on CPS construction and function. CPS, as an advanced procedure system, does not only have the function of electronic indication for operation procedures, but also have the ability to monitor plant data, process the data and then present the status of the procedure steps to the reactor operator. In addition, advantages of CPS compared with paper-based procedures and comparison with digital operating system of one M310 plus advanced nuclear power plant are described. Moreover, based on current situation, this paper offers several suggestions on CPS localization for Sanmen AP1000 nuclear power project. Besides, the last part of this paper discusses problems we might meet during the process of CPS localization. (author)

  15. Tetrazole amphiphile inducing growth of conducting polymers hierarchical nanostructures and their electromagnetic absorption properties

    Science.gov (United States)

    Xie, Aming; Sun, Mengxiao; Zhang, Kun; Xia, Yilu; Wu, Fan

    2018-05-01

    Conducting polymers (CPs) at nano scales endow materials with special optical, electrical, and magnetic properties. The crucial factor to construct and regulate the micro-structures of CPs is the inducing reagent, particular in its chemical structure, such active sites, self-assembling properties. In this paper, we design and synthesize an amphiphile bearing tetrazole moiety on its skeleton, and use this amphiphile as an inducing reagent to prepare and regulate the micro-structures of a series of CPs including polypyrrole, polyaniline, poly(3,4-ethylenedioxythiophene) and poly(p-phenylenediamine). Because of the unique electric properties of CPs and size effect, we next explored the electromagnetic absorption performances of these CPs nanostructures. A synergetic combination of electric loss and magnetic loss is used to explain the absorption mechanism of these CPs nano-structures.

  16. Conducting Polymers and Their Applications in Diabetes Management

    Directory of Open Access Journals (Sweden)

    Yu Zhao

    2016-10-01

    Full Text Available Advances in conducting polymers (CPs have promoted the development of diabetic monitoring and treatment, which is of great significance in human healthcare and modern medicine. CPs are special polymers with physical and electrochemical features resembling metals, inorganic semiconductors and non-conducting polymers. To improve and extend their properties, the fabrication of CPs and CP composites has attracted intensive attention in recent decades. Some CPs are biocompatible and suitable for biomedical use. Thus, the intriguing properties of CPs make wearable, noninvasive, continuous diabetes managing devices and other potential applications in diabetes possible in the near future. To highlight the recent advances of CPs and their derived materials (especially in conducting polymer hydrogels, here we discuss their fabrication and characterization, review the current state-of-the-art research in diabetes management based on these materials and describe current challenges as well as future potential research directions.

  17. Security and privacy in cyber-physical systems foundations, principles, and applications

    CERN Document Server

    Song, Houbing; Jeschke, Sabina

    2017-01-01

    Written by a team of experts at the forefront of the cyber-physical systems (CPS) revolution, this book provides an in-depth look at security and privacy, two of the most critical challenges facing both the CPS research and development community and ICT professionals. It explores, in depth, the key technical, social, and legal issues at stake, and it provides readers with the information they need to advance research and development in this exciting area. Cyber-physical systems (CPS) are engineered systems that are built from, and depend upon the seamless integration of computational algorithms and physical components. Advances in CPS will enable capability, adaptability, scalability, resiliency, safety, security, and usability far in excess of what today's simple embedded systems can provide. Just as the Internet revolutionized the way we interact with information, CPS technology has already begun to transform the way people interact with engineered systems. In the years ahead, smart CPS will drive innovat...

  18. Software Engineering Issues for Cyber-Physical Systems

    DEFF Research Database (Denmark)

    Al-Jaroodi, Jameela; Mohamed, Nader; Jawhar, Imad

    2016-01-01

    step; however, designing and implementing the right software to integrate and use them effectively is essential. The software facilitates better interfaces, more control and adds smart services, high flexibility and many other added values and features to the CPS. However, software development for CPS......Cyber-Physical Systems (CPS) provide many smart features for enhancing physical processes. These systems are designed with a set of distributed hardware, software, and network components that are embedded in physical systems and environments or attached to humans. Together they function seamlessly...... to offer specific functionalities or features that help enhance human lives, operations or environments. While different CPS components play important roles in a successful CPS development, the software plays the most important role among them. Acquiring and using high quality CPS components is the first...

  19. Structural analysis of the core COMPASS family of histone H3K4 methylases from yeast to human.

    Science.gov (United States)

    Takahashi, Yoh-hei; Westfield, Gerwin H; Oleskie, Austin N; Trievel, Raymond C; Shilatifard, Ali; Skiniotis, Georgios

    2011-12-20

    Histone H3 lysine 4 (H3K4) methylation is catalyzed by the highly evolutionarily conserved multiprotein complex known as Set1/COMPASS or MLL/COMPASS-like complexes from yeast to human, respectively. Here we have reconstituted fully functional yeast Set1/COMPASS and human MLL/COMPASS-like complex in vitro and have identified the minimum subunit composition required for histone H3K4 methylation. These subunits include the methyltransferase C-terminal SET domain of Set1/MLL, Cps60/Ash2L, Cps50/RbBP5, Cps30/WDR5, and Cps25/Dpy30, which are all common components of the COMPASS family from yeast to human. Three-dimensional (3D) cryo-EM reconstructions of the core yeast complex, combined with immunolabeling and two-dimensional (2D) EM analysis of the individual subcomplexes reveal a Y-shaped architecture with Cps50 and Cps30 localizing on the top two adjacent lobes and Cps60-Cps25 forming the base at the bottom. EM analysis of the human complex reveals a striking similarity to its yeast counterpart, suggesting a common subunit organization. The SET domain of Set1 is located at the juncture of Cps50, Cps30, and the Cps60-Cps25 module, lining the walls of a central channel that may act as the platform for catalysis and regulative processing of various degrees of H3K4 methylation. This structural arrangement suggested that COMPASS family members function as exo-methylases, which we have confirmed by in vitro and in vivo studies.

  20. Using the Pareto Distribution to Improve Estimates of Topcoded Earnings

    OpenAIRE

    Philip Armour; Richard V. Burkhauser; Jeff Larrimore

    2014-01-01

    Inconsistent censoring in the public-use March Current Population Survey (CPS) limits its usefulness in measuring labor earnings trends. Using Pareto estimation methods with less-censored internal CPS data, we create an enhanced cell-mean series to capture top earnings in the public-use CPS. We find that previous approaches for imputing topcoded earnings systematically understate top earnings. Annual earnings inequality trends since 1963 using our series closely approximate those found by Kop...

  1. TREM-1 expression in craniopharyngioma and Rathke's cleft cyst: its possible implication for controversial pathology.

    Science.gov (United States)

    Liu, Yi; Wang, Chao-Hu; Li, Dan-Ling; Zhang, Shi-Chao; Peng, Yu-Ping; Peng, Jun-Xiang; Song, Ye; Qi, Song-Tao; Pan, Jun

    2016-08-02

    Whether a mixed type of craniopharyngioma (CP) exists and whether papillary craniopharyngioma (pCP) is on a histopathological continuum with Rathke's cleft cyst (RCC) remain controversial. Herein, we examined the expression and localization of β-catenin, BRAF p.V600E (V600E), and triggering receptor expressed on myeloid cells-1 (TREM-1) in 58 samples including 20 pCPs, 26 adamantinomatous craniopharyngiomas (aCP), and 12 RCCs. Five aCPs were diagnosed with mixed type CPs and the remaining 21 cases were pure aCPs. Four of the 12 RCCs presented with significant squamous epithelium (SE). V600E immunoreactivity was observed in all pCPs in the cytoplasm, but not in the nuclei. aCPs and RCCs, including mixed type CP, did not express V600E. Nuclear β-catenin translocation was detected exclusively in aCPs. TREM-1 was expressed in pCPs. Additionally, TREM-1 expression was detected in the SE of 5 "mixed type" CPs, while it was absent in pure aCPs. TREM-1 was expressed in 4 RCCs with SE, but not in the remaining 8 RCCs. TREM-1 mRNA levels were compared in cultured pCP and aCP cells. TREM-1 mRNA level was significantly (p < 0.001; up to 4.045 fold) higher in pCPs than in aCPs. Western blotting revealed a significantly (p < 0.001; up to 7.19 fold) lower level of TREM-1 expression in aCP cells compared to that in pCP cells. Our findings further supported that RCC and pCP may represent two ends of a morphological spectrum. A variant showing overlapping histological features of aCP and pCP should not be considered as a mixed type.

  2. Dark membrane lysis and photosensitization by 3-carbethoxypsoralen

    Energy Technology Data Exchange (ETDEWEB)

    Muller-Runkel, R.; Grossweiner, L.I. (Illinois Inst. of Tech., Chicago (USA). Dept. of Physics)

    1981-03-01

    Aqueous solutions of 3-carbethoxypsoralen (3-CPs) induced lysis of egg lecithin liposomes and whole human erythrocytes in the dark. Near-UV irradiation of 3-CPs sensitized the inactivation of lysozyme attributed to the production of reactive radical intermediates. The implications of these findings for the use of 3-CPs as a sensitizer in psoralen + UV-A (PUVA) therapy of psoriasis are discussed.

  3. Dark membrane lysis and photosensitization by 3-carbethoxypsoralen

    International Nuclear Information System (INIS)

    Muller-Runkel, R.; Grossweiner, L.I.

    1981-01-01

    Aqueous solutions of 3-carbethoxypsoralen (3-CPs) induced lysis of egg lecithin liposomes and whole human erythrocytes in the dark. Near-UV irradiation of 3-CPs sensitized the inactivation of lysozyme attributed to the production of reactive radical intermediates. The implications of these findings for the use of 3-CPs as a sensitizer in psoralen + UV-A (PUVA) therapy of psoriasis are discussed. (author)

  4. Intellectual Disabilities and Neglectful Parenting: Preliminary Findings on the Role of Cognition in Parenting Risk

    OpenAIRE

    Azar, Sandra T.; Stevenson, Michael T.; Johnson, David R.

    2012-01-01

    Parents with intellectual disabilities (PID) are over-represented in the child protective services (CPS) system. This study examined a more nuanced view of the role of cognition in parenting risk. Its goal was to validate a social information processing (SIP) model of child neglect that draws on social cognition research and advances in neuroscience. Mothers who had CPS child neglect cases were compared with mothers with no CPS involvement on a set of SIP factors. Mothers with low IQs were ov...

  5. Future Manufacturing Systems in Norway – Strategy, Architecture and Framework

    OpenAIRE

    Kolla, Sri Sudha Vijay Keshav

    2016-01-01

    This study investigates the suitability of Cyber Physical Systems (CPS) in Norwegian manufacturing industries and its implementation. This study explores the research and innovation needs in Norway which will be given as inputs to Strategic Research Agenda (SRA) 2030 of European Commission to share future manufacturing strategies in Norway. The objectives of the research are to identifying the opportunities and challenges of CPS, developing a feasible reference architecture of CPS which benef...

  6. Modélisation conjointe de la sûreté et de la sécurité pour l’évaluation des risques dans les systèmes cyber-physiques

    OpenAIRE

    Kriaa , Siwar

    2016-01-01

    Cyber physical systems (CPS) denote systems that embed programmable components in order to control a physical process or infrastructure. CPS are henceforth widely used in different industries like energy, aeronautics, automotive, medical or chemical industry. Among the variety of existing CPS stand SCADA (Supervisory Control And Data Acquisition) systems that offer the necessary means to control and supervise critical infrastructures. Their failure or malfunction can engender adverse conseque...

  7. How to Maintain Computerized Procedure System in the same Version

    International Nuclear Information System (INIS)

    Jung, Yeon Sub

    2016-01-01

    CPS(Computerized Procedure System) has been introduced in advanced nuclear power plant worldwide. Korean CPS complies with this trend. It has been applied to Shinkori3,4 and all their successors including BNPP1,2,3,4. CPS is designed by KHNP CRI, and developed by Westinghouse or Doosan. Initial design has been improved by reflecting operator experience, human factor V and V, and advanced engineering method. Design improvement makes CPS differ from plant to plant. For example CPS in Shinhanul cannot interpret CP(Computerized Procedure) of ShinKori3, 4. Different CPS makes it difficult to utilize CP and train operators. Therefore it is important to keep CPS in single version. Note that typical text editors in the office are kept in single version. On the other hand, plant monitoring systems in main control room are actually different. Because CPS is positioned between text editor and monitoring system, goal to maintain CPS in single version is not an easy task. From Shinkori3,4, lots of improvements are achieved in CPS. This improvement surely makes operation easy and will not introduce human errors. Side effect of improvement is that PXS and CPS ES may not be compatible among nuclear power plants. So the side effect should be avoided by minimizing change of XML. Initial XML had been developed for Shinkori3,4. The XML has been modified slightly for Shinhanul1,2. PXS and CPS ES are being developed for the same version for all nuclear power plants of APR1400

  8. Customer premises services market demand assessment 1980 - 2000. Volume 1: Executive summary

    Science.gov (United States)

    Gamble, R. B.; Saporta, L.; Heidenrich, G. A.

    1983-01-01

    Estimates of market demand for domestic civilian telecommunications services for the years 1980 to 2000 are provided. Overall demand, demand or satellite services, demand for satellite delivered Customer Premises Service (CPS), and demand for 30/20 GHz Customer Premises Services are covered. Emphasis is placed on the CPS market and demand is segmented by market, by service, by user class and by geographic region. Prices for competing services are discussed and the distribution of traffic with respect to distance is estimated. A nationwide traffic distribution model for CPS in terms of demand for CPS traffic and earth stations for each of the major SMSAs in the United States are provided.

  9. Mac protocols for cyber-physical systems

    CERN Document Server

    Xia, Feng

    2015-01-01

    This book provides a literature review of various wireless MAC protocols and techniques for achieving real-time and reliable communications in the context of cyber-physical systems (CPS). The evaluation analysis of IEEE 802.15.4 for CPS therein will give insights into configuration and optimization of critical design parameters of MAC protocols. In addition, this book also presents the design and evaluation of an adaptive MAC protocol for medical CPS, which exemplifies how to facilitate real-time and reliable communications in CPS by exploiting IEEE 802.15.4 based MAC protocols. This book wil

  10. Recent Trends in Veteran Unemployment as Measured in the Current Population Survey and the American Community Survey

    National Research Council Canada - National Science Library

    Savych, Bogdan; Klerman, Jacob A; Loughran, David S

    2008-01-01

    ...". Analyses of CPS data indicates that veteran youth unemployment increased relative to nonveteran youth unemployment between 2003 and 2005 "and that this relative increase is statistically significant...

  11. Design and characterization of calcium phosphate ceramic scaffolds for bone tissue engineering.

    Science.gov (United States)

    Denry, Isabelle; Kuhn, Liisa T

    2016-01-01

    Our goal is to review design strategies for the fabrication of calcium phosphate ceramic scaffolds (CPS), in light of their transient role in bone tissue engineering and associated requirements for effective bone regeneration. We examine the various design options available to meet mechanical and biological requirements of CPS and later focus on the importance of proper characterization of CPS in terms of architecture, mechanical properties and time-sensitive properties such as biodegradability. Finally, relationships between in vitro versus in vivo testing are addressed, with an attempt to highlight reliable performance predictors. A combinatory design strategy should be used with CPS, taking into consideration 3D architecture, adequate surface chemistry and topography, all of which are needed to promote bone formation. CPS represent the media of choice for delivery of osteogenic factors and anti-infectives. Non-osteoblast mediated mineral deposition can confound in vitro osteogenesis testing of CPS and therefore the expression of a variety of proteins or genes including collagen type I, bone sialoprotein and osteocalcin should be confirmed in addition to increased mineral content. CPS are a superior scaffold material for bone regeneration because they actively promote osteogenesis. Biodegradability of CPS via calcium and phosphate release represents a unique asset. Structural control of CPS at the macro, micro and nanoscale and their combination with cells and polymeric materials is likely to lead to significant developments in bone tissue engineering. Copyright © 2015 Academy of Dental Materials. Published by Elsevier Ltd. All rights reserved.

  12. Preliminary Findings of Feasibility of a Wearable Soft-robotic Glove Supporting Impaired Hand Function in Daily Life

    NARCIS (Netherlands)

    Radder, Bob; Radder, B.; Prange, Grada Berendina; Prange-Lasonder, G.B.; Kottink, A.I.R.; Gaasbeek, L.; Holmberg, J.; Meyer, T.; Buurke, Jaap; Rietman, Johan Swanik

    2016-01-01

    Elderly people frequently encounter difficulties in independently performing activities of daily living (ADL) due to a reduced hand function. Robotic assistive devices have the potential to provide the assistance that is necessary to perform ADL independently without the need of personal assistance.

  13. Factors associated with increasing functional decline in multimorbid independently living older people

    NARCIS (Netherlands)

    Laan, W.; Bleijenberg, N.; Drubbel, I.; Numans, M.E.; De Wit, N.J.; Schuurmans, M.J.

    2013-01-01

    Objectives With increasing age the levels of activities of daily living (ADL) deteriorate. In this study we aimed to investigate which demographic characteristics and disorders are associated with ADL disabilities in multi-morbid older people. Study design We performed a cross-sectional study with

  14. Transfer effects of a cognitive strategy training for stroke patients with apraxia

    NARCIS (Netherlands)

    Geusgens, C. A. V.; van Heugten, C. M.; Cooijmans, J. P. J.; Jolles, J.; van den Heuvel, W. J. A.

    2007-01-01

    The objective of this study was to evaluate transfer effects of cognitive strategy training for stroke patients with apraxia. During 8 weeks, 29 apraxic patients received cognitive strategy training to teach them how to perform activities of daily living (ADL) as independently as possible. ADL

  15. Resident Choice and the Survey Process: The Need for Standardized Observation and Transparency

    Science.gov (United States)

    Schnelle, John F.; Bertrand, Rosanna; Hurd, Donna; White, Alan; Squires, David; Feuerberg, Marvin; Hickey, Kelly; Simmons, Sandra F.

    2009-01-01

    Purpose: To describe a standardized observation protocol to determine if nursing home (NH) staff offer choice to residents during 3 morning activities of daily living (ADL) and compare the observational data with deficiency statements cited by state survey staff. Design and Methods: Morning ADL care was observed in 20 NHs in 5 states by research…

  16. The impact of visual impairment on the ability to perform activities of daily living for persons with severe/profound intellectual disability

    NARCIS (Netherlands)

    Dijkhuizen, Annemarie; Hilgenkamp, Thessa I.M.; Krijnen, Wim; van der Schans, Cees; Waninge, Aly

    2015-01-01

    Background The ability to perform activities of daily living (ADL) as a component of participation is one of the factors that contribute to the quality of life. The ability to perform ADL for persons experiencing severe/profound intellectual disability (ID) may be reduced due to their cognitive and

  17. Greater Independence in Activities of Daily Living is Associated with Higher Health-Related Quality of Life Scores in Nursing Home Residents with Dementia

    Directory of Open Access Journals (Sweden)

    Charice S. Chan

    2015-06-01

    Full Text Available Health-related quality of life (HRQL for nursing home residents is important, however, the concept of quality of life is broad, encompasses many domains and is difficult to assess in people with dementia. Basic activities of daily living (ADL are measured routinely in nursing homes using the Resident Assessment Instrument-Minimum Data Set Version 2.0 (RAI-MDS and Functional Independence Measure (FIM instrument. We examined the relationship between HRQL and ADL to assess the future possibility of ADL dependency level serving as a surrogate measure of HRQL in residents with dementia. To assess ADL, measures derived from the RAI-MDS and FIM data were gathered for 111 residents at the beginning of our study and at 6-month follow-up. Higher scores for independence in ADL were correlated with higher scores for a disease-specific HRQL measure, the Quality of Life—Alzheimer’s Disease Scale. Preliminary evidence suggests that FIM-assessed ADL is associated with HRQL for these residents. The associations of the dressing and toileting items with HRQL were particularly strong. This finding suggests the importance of ADL function in HRQL. The RAI-MDS ADL scales should be used with caution to evaluate HRQL.

  18. Impact of Different Lignin Fractions on Saccharification Efficiency in Diverse Species of the Bioenergy Crop Miscanthus

    NARCIS (Netherlands)

    Weijde, van der Tim; Torres Salvador, Andres Francisco; Dolstra, Oene; Dechesne, Annemarie; Visser, Richard G.F.; Trindade, Luisa M.

    2016-01-01

    Lignin is a key factor limiting saccharification of lignocellulosic feedstocks. In this comparative study, various lignin methods—including acetyl bromide lignin (ABL), acid detergent lignin (ADL), Klason lignin (KL), and modified ADL and KL determination methods—were evaluated for their

  19. Causes of decreased activity of daily life in elderly patients who need daily living care.

    Science.gov (United States)

    Yoshino, Hiroshi; Sakurai, Takashi; Hasegawa, Kazuo; Yokono, Koichi

    2011-07-01

    The causes of decreased activity of daily life (ADL) in elderly patients include cerebrovascular diseases, bone fracture by falls, and dementia. The present study was conducted among elderly patients with decreased ADL who were hospitalized in nursing wards in order to investigate the causes of becoming early bedridden and to determine precautionary measures against decreased ADL. The study subjects were 224 elderly patients with decreased ADL (mean age: 83.3 ± 8.0 years) and 49 outpatients without decreased ADL (mean age: 76.8 ± 5.3 years). Current age, age at the start of ADL decrease, medical history and history of smoking were investigated. In the groups with decreased ADL, current age and the age of becoming bedridden in non-diabetic versus diabetic groups were 84.7 ± 7.9 versus 80.3 ± 7.5 and 82.7 ± 8.3 versus 77.6 ± 8.0 years, respectively, both showing significantly lower values in the diabetic group (P bedridden. Diabetic patients with smoking habit were significantly younger than diabetic and non-diabetic patients without smoking habit. Sex difference, smoking habit and presence of diabetes mellitus are independent risk factors of becoming early bedridden. Therefore, the major targets of medical care among elderly should be diabetic men with a smoking habit to lower the risks of decreased ADL. © 2011 Japan Geriatrics Society.

  20. Understanding implementation of comprehensive geriatric care programs: a multiple perspective approach is preferred

    NARCIS (Netherlands)

    J.B.M. Vos; J.M. Cramm (Jane); J.D.H. van Wijngaarden (Jeroen); T.J.E.M. Bakker (Ton); J.P. Mackenbach (Johan); A.P. Nieboer (Anna)

    2017-01-01

    textabstractBackground: The Prevention and Reactivation Care Program (PReCaP) provides a novel approach targeting hospital-related functional decline among elderly patients. Despite the high expectations, the PReCaP was not effective in preventing functional decline (ADL and iADL) among older

  1. The Impact of Leisure and Social Activities on Activities of Daily Living of Middle-Aged Adults: Evidence from a National Longitudinal Survey in Japan.

    Directory of Open Access Journals (Sweden)

    Takafumi Monma

    Full Text Available This study investigated the effects of leisure and social activities on the ability of middle-aged adults to maintain activities of daily living (ADL, and whether performing these activities alone or with others contributed to the ability to perform ADL. The study used nationally representative longitudinal data of 22,770 adults in Japan, aged 50-59 years, who did not have limitations in performing ADL at the beginning of the 5-year survey period. The study considered six activity categories: two leisure activities ("hobbies or cultural activities" and "exercise or sports" and four social activities ("community events," "support for children," "support for elderly individuals," and "other social activities". Multiple logistic regression analysis was used to examine the relation between participation in these categories at baseline and difficulties in ADL at the 5-year follow-up. The association between the extent of social interaction during these activities ("by oneself," "with others," or "both" and difficulties in ADL was also investigated. The analysis yielded significant negative correlations between "exercise or sports" and difficulties in ADL for both men and women, and between "hobbies or cultural activities" and difficulties in ADL for women. However, these significant relationships occurred only when activities were conducted "with others." The present findings might help prevent deterioration in middle-aged adults' performance of ADL in Japan.

  2. The Hamlet design entry system: on the implementation of synchronous channels

    NARCIS (Netherlands)

    M.R. van Steen

    1994-01-01

    textabstractThe graphical Hamlet Application Design Language (ADL) has been developed to support the construction of parallel applications. The language is based on a notion of processes communicating by means of message-passing. One of the goals of ADL is that its implementation should allow

  3. Mental Status as a Predictor of Daily Function in Progressive Dementia.

    Science.gov (United States)

    Reed, Bruce R.; And Others

    1989-01-01

    Compared Mini Mental Status Exam (MMSE) scores and activities of daily living (ADL) scores from 59 patients with progressive dementias. MMSE scores explained approximately one-third of variance in both instrumental and physical ADLs. Findings suggest that cognitive losses and functional impairments are 2 distinct aspects of dementia severity which…

  4. The impact of visual impairment on the ability to perform activities of daily living for persons with severe/profound intellectual disability

    NARCIS (Netherlands)

    Dijkhuizen, Annemarie; Hilgenkamp, Thessa I. M.; Krijnen, Wim P.; Schans, van der Cees P.; Waninge, Aly

    Background: The ability to perform activities of daily living (ADL) as a component of participation is one of the factors that contribute to quality of life. The ability to perform ADL for persons experiencing severe/profound intellectual disability (ID) may be reduced due to their cognitive and

  5. Activities of daily living, depression, and quality of life in Parkinson's disease.

    Directory of Open Access Journals (Sweden)

    Blake J Lawrence

    Full Text Available This study examined whether activities of daily living (ADL mediate the relationship between depression and health-related quality of life (HR-QOL in people with Parkinson's disease (PD. A cross-sectional, correlational research design examined data from 174 participants who completed the Geriatric Depression Scale (GDS-15, Parkinson's Disease Questionnaire-39 (PDQ-39, and Unified Parkinson's Disease Rating Scale-section 2 (UPDRS-section 2 [ADL]. Multiple Regression Analysis (MRA was used to examine the mediator model. Depression and ADL significantly (p<.001 predicted HR-QOL, and depression significantly (p<.001 predicted ADL. Whilst ADL did not impact on the relationship between depression and HR-QOL, there was a significant (p<.001 indirect effect of depression on HR-QOL via ADL, suggesting both direct and indirect (via ADL effects of depression on HR-QOL. The magnitude of this effect was moderate (R2 = .13. People with PD who report depression also experience greater difficulty completing ADL, which impacts upon their HR-QOL. It is recommended that clinicians adopt a multidisciplinary approach to care by combining pharmacological treatments with psycho/occupational therapy, thereby alleviating the heterogeneous impact of motor and non-motor symptoms on HR-QOL in people with PD.

  6. Self-efficacy blandt apopleksipatienter

    DEFF Research Database (Denmark)

    Kristensen, Lola Qvist ,; Pallesen, Hanne

    2017-01-01

    Baggrund Flere og flere mennesker lever med følgerne af apopleksi, herunder fysiske og kognitive vanskeligheder, som begrænser mobilitet og ADL-evne. Studier har vist, at høj self-effi cacy (oplevet handlekompetence) er associeret med bedre mobilitet og ADL-evne samtidig med at det kan fremme liv...

  7. A systematic review of instruments for assessment of capacity in activities of daily living in children with developmental co-ordination disorder

    NARCIS (Netherlands)

    van der Linde, B W; van Netten, J J; Otten, E; Postema, K; Geuze, R H; Schoemaker, M M

    Children with developmental co-ordination disorder (DCD) face evident motor difficulties in activities of daily living (ADL). Assessment of their capacity in ADL is essential for diagnosis and intervention, in order to limit the daily consequences of the disorder. The aim of this study is to

  8. Observation-based assessment of functional ability in patients with chronic widespread pain

    DEFF Research Database (Denmark)

    Amris, Kirstine; Wæhrens, Eva Ejlersen; Jespersen, Anders

    2011-01-01

    Knowledge about functional ability, including activities of daily living (ADL), in patients with chronic widespread pain (CWP) and fibromyalgia (FMS) is largely based on self-report. The purpose of this study was to assess functional ability by using standardised, observation-based assessment...... of ADL performance and to examine the relationship between self-reported and observation-based measures of disability. A total of 257 women with CWP, 199 (77%) fulfilling the American College of Rheumatology tender point criteria for FMS, were evaluated with the Assessment of Motor and Process Skills...... (AMPS), an observation-based assessment providing linear measures of ADL motor and ADL process skill ability (unit: logits). A cutoff for effortless and independent ADL task performance is set at 2.0 for the motor scale and 1.0 for the process scale. A total of 248 (96.5%) had ability measures below...

  9. Observation-based assessment of functional ability in patients with chronic widespread pain: A cross-sectional study

    DEFF Research Database (Denmark)

    Amris, Kirstine; Wæhrens, Eva Elisabet Ejlersen; Jespersen, Anders

    2011-01-01

    Knowledge about functional ability, including activities of daily living (ADL), in patients with chronic widespread pain (CWP) and fibromyalgia (FMS) is largely based on self-report. The purpose of this study was to assess functional ability by using standardised, observation-based assessment...... of ADL performance and to examine the relationship between self-reported and observation-based measures of disability. A total of 257 women with CWP, 199 (77%) fulfilling the American College of Rheumatology tender point criteria for FMS, were evaluated with the Assessment of Motor and Process Skills...... (AMPS), an observation-based assessment providing linear measures of ADL motor and ADL process skill ability (unit: logits). A cutoff for effortless and independent ADL task performance is set at 2.0 for the motor scale and 1.0 for the process scale. A total of 248 (96.5%) had ability measures below...

  10. A "client-centred activities of daily living" intervention for persons with stroke

    DEFF Research Database (Denmark)

    Guidetti, Susanne; Ranner, Maria; Tham, Kerstin

    2015-01-01

    OBJECTIVE: To compare changes regarding perceived participation, independence in activities of daily living (ADL) and life satisfaction between 3, 6 and 12 months after inclusion in a study of a client-centred ADL intervention and usual ADL intervention after stroke. DESIGN: A multicentre...... diagnosed with dementia, and were able to understand instructions. Data collection was performed by blinded assessors. The primary outcome, perceived participation, was assessed with the Stroke Impact Scale 3.0, domain 8. The secondary outcomes, participation, independence in ADL, and life satisfaction......, were assessed with validated instruments. For statistical power, 280 participants were required. Statistical analyses were performed on an intention-to-treat basis. RESULTS: There were no differences between the groups regarding changes in perceived participation, independence in ADL, or life...

  11. Effects of fumaric acid supplementation on methane production and rumen fermentation in goats fed diets varying in forage and concentrate particle size.

    Science.gov (United States)

    Li, Zongjun; Liu, Nannan; Cao, Yangchun; Jin, Chunjia; Li, Fei; Cai, Chuanjiang; Yao, Junhu

    2018-01-01

    In rumen fermentation, fumaric acid (FA) could competitively utilize hydrogen with methanogenesis to enhance propionate production and suppress methane emission, but both effects were diet-dependent. This study aimed to explore the effects of FA supplementation on methanogenesis and rumen fermentation in goats fed diets varying in forage and concentrate particle size. Four rumen-cannulated goats were used in a 4 × 4 Latin square design with a 2 × 2 factorial arrangement of treatments: low or high ratio of forage particle size: concentrate particle size (Fps:Cps), without or with FA supplementation (24 g/d). Fps:Cps was higher in the diet with chopped alfalfa hay plus ground corn than in that with ground alfalfa hay plus crushed corn. Both increasing dietary Fps:Cps and FA supplementation shifted ruminal volatile fatty acid (VFA) patterns toward more propionate and less acetate in goats. An interaction between dietary Fps:Cps and FA supplementation was observed for the ratio of acetate to propionate (A:P), which was more predominant when FA was supplemented in the low-Fps:Cps diet. Methane production was reduced by FA, and the reduction was larger in the low-Fps:Cps diet (31.72%) than in the high-Fps:Cps diet (17.91%). Fumaric acid decreased ruminal total VFA concentration and increased ruminal pH. No difference was found in ruminal DM degradation of concentrate or alfalfa hay by dietary Fps:Cps or FA. Goats presented a lower ruminal methanogen abundance with FA supplementation and a higher B. fibrisolvens abundance with high dietary Fps:Cps. Adjusting dietary Fps:Cps is an alternative dietary model for studying diet-dependent effects without changing dietary chemical composition. Fumaric acid supplementation in the low-Fps:Cps diet showed greater responses in methane mitigation and propionate increase.

  12. Capsular Sialyltransferase Specificity Mediates Different Phenotypes in Streptococcus suis and Group B Streptococcus

    Directory of Open Access Journals (Sweden)

    David Roy

    2018-04-01

    Full Text Available The capsular polysaccharide (CPS represents a key virulence factor for most encapsulated streptococci. Streptococcus suis and Group B Streptococcus (GBS are both well-encapsulated pathogens of clinical importance in veterinary and/or human medicine and responsible for invasive systemic diseases. S. suis and GBS are the only Gram-positive bacteria which express a sialylated CPS at their surface. An important difference between these two sialylated CPSs is the linkage between the side-chain terminal galactose and sialic acid, being α-2,6 for S. suis but α-2,3 for GBS. It is still unclear how sialic acid may affect CPS production and, consequently, the pathogenesis of the disease caused by these two bacterial pathogens. Here, we investigated the role of sialic acid and the putative effect of sialic acid linkage modification in CPS synthesis using inter-species allelic exchange mutagenesis. To this aim, a new molecular biogenetic approach to express CPS with modified sialic acid linkage was developed. We showed that sialic acid (and its α-2,6 linkage is crucial for S. suis CPS synthesis, whereas for GBS, CPS synthesis may occur in presence of an α-2,6 sialyltransferase or in absence of sialic acid moiety. To evaluate the effect of the CPS composition/structure on sialyltransferase activity, two distinct capsular serotypes within each bacterial species were compared (S. suis serotypes 2 and 14 and GBS serotypes III and V. It was demonstrated that the observed differences in sialyltransferase activity and specificity between S. suis and GBS were serotype unrestricted. This is the first time that a study investigates the interspecies exchange of capsular sialyltransferase genes in Gram-positive bacteria. The obtained mutants represent novel tools that could be used to further investigate the immunomodulatory properties of sialylated CPSs. Finally, in spite of common CPS structural characteristics and similarities in the cps loci, sialic acid exerts

  13. Molecular mapping of the cell wall polysaccharides of the human pathogen Streptococcus agalactiae

    Science.gov (United States)

    Beaussart, Audrey; Péchoux, Christine; Trieu-Cuot, Patrick; Hols, Pascal; Mistou, Michel-Yves; Dufrêne, Yves F.

    2014-11-01

    The surface of many bacterial pathogens is covered with polysaccharides that play important roles in mediating pathogen-host interactions. In Streptococcus agalactiae, the capsular polysaccharide (CPS) is recognized as a major virulence factor while the group B carbohydrate (GBC) is crucial for peptidoglycan biosynthesis and cell division. Despite the important roles of CPS and GBC, there is little information available on the molecular organization of these glycopolymers on the cell surface. Here, we use atomic force microscopy (AFM) and transmission electron microscopy (TEM) to analyze the nanoscale distribution of CPS and GBC in wild-type (WT) and mutant strains of S. agalactiae. TEM analyses reveal that in WT bacteria, peptidoglycan is covered with a very thin (few nm) layer of GBC (the ``pellicle'') overlaid by a 15-45 nm thick layer of CPS (the ``capsule''). AFM-based single-molecule mapping with specific antibody probes shows that CPS is exposed on WT cells, while it is hardly detected on mutant cells impaired in CPS production (ΔcpsE mutant). By contrast, both TEM and AFM show that CPS is over-expressed in mutant cells altered in GBC expression (ΔgbcO mutant), indicating that the production of the two surface glycopolymers is coordinated in WT cells. In addition, AFM topographic imaging and molecular mapping with specific lectin probes demonstrate that removal of CPScpsE), but not of GBC (ΔgbcO), leads to the exposure of peptidoglycan, organized into 25 nm wide bands running parallel to the septum. These results indicate that CPS forms a homogeneous barrier protecting the underlying peptidoglycan from environmental exposure, while the presence of GBC does not prevent peptidoglycan detection. This work shows that single-molecule AFM, combined with high-resolution TEM, represents a powerful platform for analysing the molecular arrangement of the cell wall polymers of bacterial pathogens.

  14. Oncologic emergencies in a cancer center emergency department and in general emergency departments countywide and nationwide.

    Science.gov (United States)

    Yang, Zhi; Yang, Runxiang; Kwak, Min Ji; Qdaisat, Aiham; Lin, Junzhong; Begley, Charles E; Reyes-Gibby, Cielito C; Yeung, Sai-Ching Jim

    2018-01-01

    Although cancer patients (CPs) are increasingly likely to visit emergency department (ED), no population-based study has compared the characteristics of CPs and non-cancer patients (NCPs) who visit the ED and examined factors associated with hospitalization via the ED. In this study, we (1) compared characteristics and diagnoses between CPs and NCPs who visited the ED in a cancer center or general hospital; (2) compared characteristics and diagnoses between CPs and NCPs who were hospitalized via the ED in a cancer center or general hospital; and (3) investigated important factors associated with such hospitalization. We analyzed patient characteristic and diagnosis [based on International Classification of Diseases-9 (ICD-9) codes] data from the ED of a comprehensive cancer center (MDACC), 24 general EDs in Harris County, Texas (HCED), and the National Hospital Ambulatory Medical Care Survey (NHAMCS) from 1/1/2007-12/31/2009. Approximately 3.4 million ED visits were analyzed: 47,245, 3,248,973, and 104,566 visits for MDACC, HCED, and NHAMCS, respectively, of which 44,143 (93.4%), 44,583 (1.4%), and 632 (0.6%) were CP visits. CPs were older than NCPs and stayed longer in EDs. Lung, gastrointestinal (excluding colorectal), and genitourinary (excluding prostate) cancers were the three most common diagnoses related to ED visits at general EDs. CPs visiting MDACC were more likely than CPs visiting HCED to be privately insured. CPs were more likely than NCPs to be hospitalized. Pneumonia and influenza, fluid and electrolyte disorders, and fever were important predictive factors for CP hospitalization; coronary artery disease, cerebrovascular disease, and heart failure were important factors for NCP hospitalization. CPs consumed more ED resources than NCPs and had a higher hospitalization rate. Given the differences in characteristics and diagnoses between CPs and NCPs, ED physicians must pay special attention to CPs and be familiar with their unique set of oncologic

  15. Kentteki Yabancıların Sosyal Medya Aracılığıyla Bir Araya Gelişi: “Muğla İtiraf” adlı Facebook Sayfası Üzerine Bir Örnek Olay Analizi / Strangers in the City Coming Together through Social Media: A Case Study Analysis on “Muğla Confession” Facebook Page

    Directory of Open Access Journals (Sweden)

    Pınar BAYRAM

    2016-01-01

    Full Text Available Günümüzün en yaygın iletişim kanallarından biri olan sosyal medya, her gün milyonlarca insanı bir araya getirmektedir. Sosyal medya aracılığıyla, bir araya gelen “yabancılar”, yabancı kalarak (kimliğini deşifre etmeden birbirlerine “ne”yi (hangi mesajı iletir? Sosyal medya kullanımının insani ilişkiler üzerinde ne gibi bir etkisi var? Bu soruların yanıtını arayan çalışmanın, aynı zamanda sosyal medya çalışmalarına katkı sağlama amacı da bulunmaktadır. Bu bağlamda çalışma için seçilen örneklem, facebook sitesinde yer alarak 2013 yılından günümüze dek aktif olarak kullanılan ve 3 Kasım 2014’te 15.094 takipçisi bulunan “Muğla İtiraf” isimli sayfadır. Çalışmada, belirtilen tarihler arasında, sayfada paylaşılan gönderiler incelenmiş ve paylaşım yoğunluklarına göre kategorileştirilmiştir. Buna göre en yoğun paylaşımlar, şikayet, beklenti ve deşifre odaklı olmuştur. Çalışmanın teorik çerçevesini ise Zygmunt Baumann’ın insani ilişkiler yaklaşımı ve Huizinga’nın oyun teorisi oluşturmuştur. / Social media, one of the most widespread communication channels of today, brings together millions of people every day. What (which message do the strangers who come together through social media convey to each other by remaining stranger (without revealing their identity? What kind of impacts do social media usage have on people’s lives? The study seeks answers to this question and it aims to make contribution to social media studies. In this context the sample chosen for the study is the “Muğla Confessions” page which is active since 2013 on Facebook site and has 15.094 followers on the 3rd of November, 2014. In the paper the messages shared on the page between the given dates has been examined and categorised according to their sharing traffic. Accordingly the most frequent sharings are complaints, expectation and decipher. Theoretical framework of the study is provided by Zygmunt Baumann’s humane relations theory and Huizinga’s game theory.

  16. The effects of movement stimulation on activities of daily living performance and quality of life in nursing home residents with dementia: a randomized controlled trial

    Directory of Open Access Journals (Sweden)

    Henskens M

    2018-04-01

    Full Text Available Marinda Henskens,1 Ilse M Nauta,2 Katja T Drost,3 Erik JA Scherder1 1Department of Clinical Neuropsychology, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands; 2Department of Neurology, MS Center Amsterdam, Vrije Universiteit Medical Center, Amsterdam, the Netherlands; 3tanteLouise, Bergen op Zoom, the Netherlands Background: Nursing home (NH residents with dementia experience a reduced quality of life (QoL, in part, due to a dependence in performing activities of daily living (ADL. Stimulating movement is associated with improvements in ADL performance. Therefore, movement stimulating interventions, such as ADL training and exercise, focus on optimizing ADL performance to improve QoL. This study aimed to evaluate the effect of three movement stimulating interventions on QoL and ADL performance in NH residents with dementia. Methods: In this 6-month double parallel randomized controlled trial, the effects of ADL training, a multicomponent aerobic and strength exercise training, and a combined ADL and exercise training were analyzed in 87 NH residents with dementia. The Global Deterioration Scale was used to classify the severity of dementia. Participants were screened at baseline using the 6 minute walk test and Mini-Mental State Examination. The Qualidem, and the Care Dependency Scale and Erlangen ADL test were evaluated at baseline, and after 3 and 6 months to measure QoL and ADL, respectively. Multilevel analyses were adjusted for baseline performance, age, and gender. Results: A 6-month ADL training positively affected overall QoL (p = 0.004 and multiple aspects of QoL, including care relationship (p = 0.004, positive self-image (p = 0.002, and feeling at home (p = 0.001, compared to care-as-usual. No benefits were observed of exercise on QoL. No benefits were observed of a combined ADL and exercise intervention on QoL. No effects were found of the three movement interventions on ADL performance. Conclusion: The results indicate

  17. The Development of Complex Problem Solving in Adolescence: A Latent Growth Curve Analysis

    Science.gov (United States)

    Frischkorn, Gidon T.; Greiff, Samuel; Wüstenberg, Sascha

    2014-01-01

    Complex problem solving (CPS) as a cross-curricular competence has recently attracted more attention in educational psychology as indicated by its implementation in international educational large-scale assessments such as the Programme for International Student Assessment. However, research on the development of CPS is scarce, and the few…

  18. Highly variable clinical phenotype of carbamylphosphate synthetase 1 deficiency in one family: an effect of allelic variation in gene expression?

    DEFF Research Database (Denmark)

    Klaus, V; Vermeulen, T; Minassian, B

    2009-01-01

    . The haplotypes containing each mutation are identical between the two patients, as are the sequences of CPS1 exons and flanking introns. Transcriptional experiments show that the abnormal CPS1 transcripts generated by both mutations are identical in these two patients. We characterize promoter and enhancer...

  19. Inhibitory effect of dietary capsaicin on liver fibrosis in mice.

    Science.gov (United States)

    Bitencourt, Shanna; Stradiot, Leslie; Verhulst, Stefaan; Thoen, Lien; Mannaerts, Inge; van Grunsven, Leo A

    2015-06-01

    Virtually all chronic liver injuries result in the activation of hepatic stellate cells (HSCs). In their activated state, these cells are the main collagen-producing cells implicated in liver fibrosis. Capsaicin (CPS), the active compound of chili peppers, can modulate the activation and migration of HSCs in vitro. Here, we evaluated the potential protective and prophylactic effects of CPS related to cholestatic and hepatotoxic-induced liver fibrosis and its possible underlying mechanism of action. Male Balb/c mice received dietary CPS after 3 days of bile duct ligation (BDL) or before and during carbon tetrachloride (CCl4 ) injections. Mice receiving dietary CPS after BDL had a significant improvement of liver fibrosis accompanied by a decrease in collagen deposition and downregulation of activation markers in isolated HSCs. In the CCl4 model, dietary CPS inhibited the upregulation of profibrogenic markers. However, CPS could not attenuate the CCl4 -induced fibrosis when it was already established. Furthermore, in vitro CPS treatment inhibited the autophagic process during HSC activation. Dietary CPS has potential benefits in the therapy of cholestatic liver fibrosis and in the prophylaxis of hepatotoxic-induced liver injury. © 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  20. Hepatotoxicity of Chlorpyrifos in Zebrafish Liver Cells by NMR-based Metabolomics

    Science.gov (United States)

    For decades chlorpyrifos (CPS) has been one of the most widely used organophosphate insecticides for a variety of agricultural and public health applications. The extensive use of CPS inevitably results in exposure to a small number of the human population. It is believed that ...

  1. Test of a Cardiology Patient Simulator with Students in Fourth-Year Electives.

    Science.gov (United States)

    Ewy, Gordon A.; And Others

    1987-01-01

    Students at five medical schools participated in an evaluation of a cardiology patient simulator (CPS), a life-size mannequin capable of simulating a wide variety of cardiovascular conditions. The CPS enhances learning both the knowledge and the skills necessary to perform a bedside cardiovascular evaluation. (Author/MLW)

  2. Kinds of Learning and the Likelihood of Future True Beliefs: Reply to Jäger on Reliabilism and the Value Problem

    OpenAIRE

    Olsson, Erik J; Jönsson, Martin

    2011-01-01

    We reply to Christoph Jager's criticism of the conditional probability solution (CPS) to the value problem for reliabilism due to Goldman and Olsson (2009). We argue that while Jager raises some legitimate concerns about the compatibility of CPS with externalist epistemology, his objections do not in the end reduce the plausibility of that solution.

  3. Functional characterization of ent-copalyl diphosphate synthase from Andrographis paniculata with putative involvement in andrographolides biosynthesis.

    Science.gov (United States)

    Shen, Qinqin; Li, Lixia; Jiang, Yu; Wang, Qiang

    2016-01-01

    To characterize the ent-copalyl diphosphate (ent-CPP) synthase involved in the biosynthetic pathway of andrographolides in a medicinal plant, Andrographis paniculata. The ent-CPP synthase (ent-CPS) gene was cloned from A. paniculata and its encoded ApCPS was demonstrated to react with (E,E,E)-geranylgeranyl diphosphate to form ent-CPP through recombinant expression in Escherichia coli. Site-directed mutagenesis of the Asp to Ala in the conserved DXDD motif of ApCPS resulted in loss of function. One Arg is located in the conserved position close to DXDD motif indicating the involvement of ApCPS in specialized metabolism. In addition, RT-PCR analysis revealed that ApCPS was expressed in all tissues of A. paniculata at all growth stages, which is consistent with andrographolides accumulating in these organs. Methyl jasmonate induced ApCPS gene expression, matching inducible accumulation of andrographolides in vivo. ApCPS is the first ent-CPS characterized in A. paniculata and is suggested to be involved in biosynthesis of andrographolides that have high pharmaceutical values.

  4. A Literature Review on Collaborative Problem Solving for College and Workforce Readiness. ETS GRE® Board Research Report. ETS GRE®-17-03. Research Report. ETS Research Report RR-17-06

    Science.gov (United States)

    Oliveri, Maria Elena; Lawless, Rene; Molloy, Hillary

    2017-01-01

    The literature and the employee and workforce surveys rank collaborative problem solving (CPS) among the top 5 most critical skills necessary for success in college and the workforce. This paper provides a review of the literature on CPS and related terms, including a discussion of their definitions, importance to higher education and workforce…

  5. Addendum 1 to CSERs 94-007 and 94-008: Use of 2.2 liter boats in muffle furnace operations at PFP

    International Nuclear Information System (INIS)

    Hess, A.L.

    1996-01-01

    This criticality safety review justifies raising the container size limit in CPS-Z-165-80621 and CPS-165-80622 to 2.3 liters, thereby allowing the use of 2.2-liter furnace boats in the Pu stabilization activities covered by these specifications

  6. A Development Method of Mobile Computerized Procedure System for the Cooperation among Field Workers and Main Control Room Operators in Korean Nuclear Power Plants

    International Nuclear Information System (INIS)

    Lee, Sun Jin; Seong, No Kyu; Jung, Yeon Sub

    2014-01-01

    Human errors can occur during the test and maintenance of steam generator, safety injection system and other various systems and devices in nuclear power plants (NPPs). Most of human errors can be improved by the human error prevention techniques such as self-check, peer-check, concurrent verification and etc. Another important technique is to share work information among main control room (MCR) operators and field workers. Various field service automation tools have been developed with recent information technology in many countries. APR1400 computerized procedure system (CPS) has been developed for the MCR operators of Shin-Kori 3 and 4 units. Especially, the concurrent verification support design is applied in the construction project of Shin-Hanul 1 and 2 CPS. It is expected that the proposed mobile CPS can enhance the reduction of human errors by supporting human error prevention techniques and information sharing. This paper describes the technical issues of the mobile CPS (mobile CPS) in the initial development stage. Based on the design of APR1400, CRI CPS has been developed and operated for SKN 3 and 4 HFE V and V and license test for the MCR operating staff. Therefore the mobile CPS will be developed by upgrading the CRI CPS with improved features

  7. Parental Leave Policies and Parents' Employment and Leave-Taking

    Science.gov (United States)

    Han, Wen-Jui; Ruhm, Christopher; Waldfogel, Jane

    2009-01-01

    We describe trends in maternal employment and leave-taking after birth of a newborn and analyze the extent to which these behaviors are influenced by parental leave policies. Data are from the June Current Population Survey (CPS) Fertility Supplements, merged with other months of the CPS, and cover the period 1987 to 1994. This time span is one…

  8. Inducibility of carbamoylphosphate synthetase (ammonia) in cultures of embryonic hepatocytes: ontogenesis of the responsiveness to hormones

    NARCIS (Netherlands)

    Lamers, W. H.; Zonneveld, D.; Charles, R.

    1984-01-01

    Glucocorticosteroids and cyclic AMP induce carbamoylphosphate synthetase (ammonia) (CPS) in rat hepatocytes. Using an enzyme immunoassay applied to hepatocyte cultures fixed in situ, it has been demonstrated that the capacity of hepatocytes to synthesize CPS in the presence of both hormones is

  9. Content Validation of Athletic Therapy Clinical Presentations in Canada

    Science.gov (United States)

    Lafave, Mark R.; Yeo, Michelle; Westbrook, Khatija; Valdez, Dennis; Eubank, Breda; McAllister, Jenelle

    2016-01-01

    Context: Competency-based education requires strong planning and a vehicle to deliver and track students' progress across their undergraduate programs. Clinical presentations (CPs) are proposed as 1 method to deliver a competency-based curriculum in a Canadian undergraduate athletic therapy program. Objective: Validation of 253 CPs. Setting:…

  10. Pharmacists in primary care. Determinants of the care-providing function of Dutch community pharmacists in primary care.

    NARCIS (Netherlands)

    Muijrers, P.E.; Knottnerus, J.A.; Sijbrandij, J.; Janknegt, R.; Grol, R.P.T.M.

    2004-01-01

    OBJECTIVE: To identify determinants of the care-providing function of the community pharmacists (CPs) to explain variations in professional practice. SETTING: The Netherlands 2001. PARTICIPANTS: 328 CPs. METHOD: A cross-sectional questionnaire survey was performed. Questionnaires were used to

  11. The Content Validity of Juvenile Psychopathy: An Empirical Examination

    Science.gov (United States)

    Lynam, Donald R.; Derefinko, Karen J.; Caspi, Avshalom; Loeber, Rolf; Stouthamer-Loeber, Magda

    2007-01-01

    This study examined the content validity of a juvenile psychopathy measure, the Childhood Psychopathy Scale (CPS; D. R. Lynam, 1997), based on a downward translation of an adult instrument, the Hare Psychopathy Checklist-Revised (PCL-R; R. D. Hare, 1991). The CPS was compared with two other indices of juvenile psychopathy: (a) an index derived…

  12. Model documentation coal market module of the National Energy Modeling System

    International Nuclear Information System (INIS)

    1997-02-01

    This report documents the objectives and the conceptual and methodological approach used in the development of the Coal Production Submodule (CPS). It provides a description of the CPS for model analysts and the public. The Coal Market Module provides annual forecasts of prices, production, and consumption of coal

  13. Advanced mobile and wearable systems

    NARCIS (Netherlands)

    Jóźwiak, L.

    2017-01-01

    The recent spectacular progress in the microelectronic, information, communication, material and sensor technologies created a big stimulus towards development of smart communicating cyber-physical systems (CPS) and Internet of Things (IoT). CPS and IoT are undergoing an explosive growth to a large

  14. Advanced mobile and wearable systems

    NARCIS (Netherlands)

    Jozwiak, L.

    The recent spectacular progress in the microelectronic, information, communication, material and sensor technologies created a big stimulus towards development of smart communicating cyber-physical systems (CPS) and Internet of Things (IoT). CPS and IoT are undergoing an explosive growth to a large

  15. What Matters for Staying On-Track and Graduating in Chicago Public Schools: A Focus on English Language Learners. Research Report

    Science.gov (United States)

    Gwynne, Julia; Pareja, Amber Stitziel; Ehrlich, Stacy B.; Allensworth, Elaine

    2012-01-01

    One out of every seven students in the Chicago Public Schools (CPS) is designated as an English language learner (ELL), and 30 percent of students in the entire district have been designated as ELLs at some point while enrolled in CPS. Many of the policies, programs, and resources targeting the needs of ELL students focus on students in elementary…

  16. Mortality is predicted by Comorbidity Polypharmacy score but not Charlson Comorbidity Index in geriatric trauma patients.

    Science.gov (United States)

    Nossaman, Vaughn E; Larsen, Brett E; DiGiacomo, Jody C; Manuelyan, Zara; Afram, Renee; Shukry, Sally; Kang, Amiee Luan; Munnangi, Swapna; Angus, L D George

    2017-09-19

    Increased life expectancy has resulted in more older patients at trauma centers. Traditional assessments of injuries alone may not be sufficient; age, comorbidities, and medications should be considered. 446 older trauma patients were analyzed in two groups, 45-65 years and <65, using Injury Severity Score (ISS), the Charlson Comorbidity Index (CCI), and Comorbidity-Polypharmacy Score (CPS). CCI and CPS were associated with HLOS in patients <65. In patients aged 45-65, only CPS was associated with HLOS. CPS was inversely associated with in-hospital mortality in patients <65, but not patients aged 45-65. CCI score was not associated with in-hospital mortality in either group. Increased CCI and CPS were associated with increased HLOS. In patients over 65, increased CPS was associated with decreased mortality. This could be due to return toward physiologic normalcy in treated patients not seen in their peers with undiagnosed or untreated comorbidities. TABLE OF CONTENTS SUMMARY: In an analysis of 446 older trauma patients, the Charlson Comorbidity Index (CCI) and Comorbidity-Polypharmacy Score (CPS) were associated with increased hospital length of stay. In patients ≥65, increased CPS had a lower mortality, possibly due to a greater return toward physiologic normalcy not present in their untreated peers. Published by Elsevier Inc.

  17. Silicon deposition in nanopores using a liquid precursor

    Science.gov (United States)

    Masuda, Takashi; Tatsuda, Narihito; Yano, Kazuhisa; Shimoda, Tatsuya

    2016-11-01

    Techniques for depositing silicon into nanosized spaces are vital for the further scaling down of next-generation devices in the semiconductor industry. In this study, we filled silicon into 3.5-nm-diameter nanopores with an aspect ratio of 70 by exploiting thermodynamic behaviour based on the van der Waals energy of vaporized cyclopentasilane (CPS). We originally synthesized CPS as a liquid precursor for semiconducting silicon. Here we used CPS as a gas source in thermal chemical vapour deposition under atmospheric pressure because vaporized CPS can fill nanopores spontaneously. Our estimation of the free energy of CPS based on Lifshitz van der Waals theory clarified the filling mechanism, where CPS vapour in the nanopores readily undergoes capillary condensation because of its large molar volume compared to those of other vapours such as water, toluene, silane, and disilane. Consequently, a liquid-specific feature was observed during the deposition process; specifically, condensed CPS penetrated into the nanopores spontaneously via capillary force. The CPS that filled the nanopores was then transformed into solid silicon by thermal decomposition at 400 °C. The developed method is expected to be used as a nanoscale silicon filling technology, which is critical for the fabrication of future quantum scale silicon devices.

  18. Individual Differences in Students' Complex Problem Solving Skills: How They Evolve and What They Imply

    Science.gov (United States)

    Wüstenberg, Sascha; Greiff, Samuel; Vainikainen, Mari-Pauliina; Murphy, Kevin

    2016-01-01

    Changes in the demands posed by increasingly complex workplaces in the 21st century have raised the importance of nonroutine skills such as complex problem solving (CPS). However, little is known about the antecedents and outcomes of CPS, especially with regard to malleable external factors such as classroom climate. To investigate the relations…

  19. A Development Method of Mobile Computerized Procedure System for the Cooperation among Field Workers and Main Control Room Operators in Korean Nuclear Power Plants

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Sun Jin; Seong, No Kyu; Jung, Yeon Sub [KHNP ,Daejeon (Korea, Republic of)

    2014-08-15

    Human errors can occur during the test and maintenance of steam generator, safety injection system and other various systems and devices in nuclear power plants (NPPs). Most of human errors can be improved by the human error prevention techniques such as self-check, peer-check, concurrent verification and etc. Another important technique is to share work information among main control room (MCR) operators and field workers. Various field service automation tools have been developed with recent information technology in many countries. APR1400 computerized procedure system (CPS) has been developed for the MCR operators of Shin-Kori 3 and 4 units. Especially, the concurrent verification support design is applied in the construction project of Shin-Hanul 1 and 2 CPS. It is expected that the proposed mobile CPS can enhance the reduction of human errors by supporting human error prevention techniques and information sharing. This paper describes the technical issues of the mobile CPS (mobile CPS) in the initial development stage. Based on the design of APR1400, CRI CPS has been developed and operated for SKN 3 and 4 HFE V and V and license test for the MCR operating staff. Therefore the mobile CPS will be developed by upgrading the CRI CPS with improved features.

  20. Engagement and action for health: the contribution of leaders' collaborative skills to partnership success.

    Science.gov (United States)

    El Ansari, Walid; Oskrochi, Reza; Phillips, Ceri

    2009-01-01

    A multi-site evaluation (survey) of five Kellogg-funded Community Partnerships (CPs) in South Africa was undertaken to explore the relationship between leadership skills and a range of 30 operational, functional and organisational factors deemed critical to successful CPs. The CPs were collaborative academic-health service-community efforts aimed at health professions education reforms. The level of agreement to eleven dichotomous ('Yes/No') leadership skills items was used to compute two measures of members' appreciation of their CPs' leadership. The associations between these measures and 30 CPs factors were explored, and the partnership factors that leadership skills explained were assessed after controlling. Respondents who perceived the leadership of their CPs favourably had more positive ratings across 30 other partnership factors than those who rated leadership skills less favourably, and were more likely to report a positive cost/ benefit ratio. In addition, respondents who viewed their CPs' leadership positively also rated the operational understanding, the communication mechanisms, as well as the rules and procedures of the CPs more favourably. Leadership skills explained between 20% and 7% of the variance of 10 partnership factors. The influence of leaders' skills in effective health-focussed partnerships is much broader than previously conceptualised.

  1. How Do They Compare? ITBS and ISAT Reading and Mathematics in the Chicago Public Schools, 1999 to 2002. Research Data Brief.

    Science.gov (United States)

    Easton, John Q.; Correa, Macarena; Luppescu, Stuart; Park, Hye-Sook; Ponisciak, Stephen; Rosenkranz, Todd; Sporte, Susan

    For several decades, the Iowa Tests of Basic Skills (ITBS) held the preeminent role in measuring student and school performance in the Chicago Public Schools (CPS), Illinois. In the context of the No Child Left Behind act and new calls for accountability, the CPS has decided to include results from the Illinois Standard Achievement Test (ISAT) in…

  2. Validity of the MicroDYN Approach: Complex Problem Solving Predicts School Grades beyond Working Memory Capacity

    Science.gov (United States)

    Schweizer, Fabian; Wustenberg, Sascha; Greiff, Samuel

    2013-01-01

    This study examines the validity of the complex problem solving (CPS) test MicroDYN by investigating a) the relation between its dimensions--rule identification (exploration strategy), rule knowledge (acquired knowledge), rule application (control performance)--and working memory capacity (WMC), and b) whether CPS predicts school grades in…

  3. What Do Employers Pay for Employees' Complex Problem Solving Skills?

    Science.gov (United States)

    Ederer, Peer; Nedelkoska, Ljubica; Patt, Alexander; Castellazzi, Silvia

    2015-01-01

    We estimate the market value that employers assign to the complex problem solving (CPS) skills of their employees, using individual-level Mincer-style wage regressions. For the purpose of the study, we collected new and unique data using psychometric measures of CPS and an extensive background questionnaire on employees' personal and work history.…

  4. A new practice-driven approach to develop software in a cyber-physical system environment

    Science.gov (United States)

    Jiang, Yiping; Chen, C. L. Philip; Duan, Junwei

    2016-02-01

    Cyber-physical system (CPS) is an emerging area, which cannot work efficiently without proper software handling of the data and business logic. Software and middleware is the soul of the CPS. The software development of CPS is a critical issue because of its complicity in a large scale realistic system. Furthermore, object-oriented approach (OOA) is often used to develop CPS software, which needs some improvements according to the characteristics of CPS. To develop software in a CPS environment, a new systematic approach is proposed in this paper. It comes from practice, and has been evolved from software companies. It consists of (A) Requirement analysis in event-oriented way, (B) architecture design in data-oriented way, (C) detailed design and coding in object-oriented way and (D) testing in event-oriented way. It is a new approach based on OOA; the difference when compared with OOA is that the proposed approach has different emphases and measures in every stage. It is more accord with the characteristics of event-driven CPS. In CPS software development, one should focus on the events more than the functions or objects. A case study of a smart home system is designed to reveal the effectiveness of the approach. It shows that the approach is also easy to be operated in the practice owing to some simplifications. The running result illustrates the validity of this approach.

  5. Ongoing Work on Automated Verification of Noisy Nonlinear Systems with Ariadne

    NARCIS (Netherlands)

    Geretti, Luca; Bresolin, Davide; Collins, Pieter; Zivanovic Gonzalez, Sanja; Villa, Tiziano

    2017-01-01

    Cyber-physical systems (CPS) are hybrid systems that commonly consist of a discrete control part that operates in a continuous environment. Hybrid automata are a convenient model for CPS suitable for formal verification. The latter is based on reachability analysis of the system to trace its hybrid

  6. School Enrollment in the United States: 2008. Population Characteristics

    Science.gov (United States)

    Davis, Jessica W.; Bauman, Kurt

    2011-01-01

    This report discusses school enrollment levels and trends in the population aged 3 and older based on data collected in 2008 by the U.S. Census Bureau in the American Community Survey (ACS) and the Current Population Survey (CPS). This is the second report in a series of reports using both ACS and CPS data to discuss school enrollment. The two…

  7. School Enrollment in the United States: 2006. Population Characteristics. Current Population Reports

    Science.gov (United States)

    Davis, Jessica W.; Bauman, Kurt J.

    2008-01-01

    This report discusses school enrollment levels and trends in the population aged 3 and older based on data collected in 2006 by the U.S. Census Bureau in the American Community Survey (ACS) and the Current Population Survey (CPS). Historically, the CPS has been the only data source used to produce school enrollment reports. This is the first…

  8. Towards False Alarm Reduction using Fuzzy If-Then Rules for Medical Cyber Physical Systems

    DEFF Research Database (Denmark)

    Li, Wenjuan; Meng, Weizhi; Su, Chunhua

    2018-01-01

    Cyber-Physical Systems (CPS) are integrations of computation, networking and physical processes. Its process control is often referred to as embedded systems. Generally, CPS and Internet of Things (IoT) have the same basic architecture, whereas the former shows a higher combination and coordination...

  9. Compositions for directed alignment of conjugated polymers

    Science.gov (United States)

    Kim, Jinsang; Kim, Bong-Gi; Jeong, Eun Jeong

    2016-04-19

    Conjugated polymers (CPs) achieve directed alignment along an applied flow field and a dichroic ratio of as high as 16.67 in emission from well-aligned thin films and fully realized anisotropic optoelectronic properties of CPs in field-effect transistor (FET).

  10. Applied cyber-physical systems

    CERN Document Server

    Suh, Sang C; Carbone, John N

    2013-01-01

    From the reviews: "This book is an edited volume with contributions from the leading experts on the topic of CPS and presents diverse application examples and challenges in CPS. … Advanced-level undergraduate and graduate students and researchers in the fields of computer science and engineering will find this book very useful as a reference." (D. Subbaram Naidu, Amazon.com, January, 2014)

  11. Light-Controlled Swarming and Assembly of Colloidal Particles

    Directory of Open Access Journals (Sweden)

    Jianhua Zhang

    2018-02-01

    Full Text Available Swarms and assemblies are ubiquitous in nature and they can perform complex collective behaviors and cooperative functions that they cannot accomplish individually. In response to light, some colloidal particles (CPs, including light active and passive CPs, can mimic their counterparts in nature and organize into complex structures that exhibit collective functions with remote controllability and high temporospatial precision. In this review, we firstly analyze the structural characteristics of swarms and assemblies of CPs and point out that light-controlled swarming and assembly of CPs are generally achieved by constructing light-responsive interactions between CPs. Then, we summarize in detail the recent advances in light-controlled swarming and assembly of CPs based on the interactions arisen from optical forces, photochemical reactions, photothermal effects, and photoisomerizations, as well as their potential applications. In the end, we also envision some challenges and future prospects of light-controlled swarming and assembly of CPs. With the increasing innovations in mechanisms and control strategies with easy operation, low cost, and arbitrary applicability, light-controlled swarming and assembly of CPs may be employed to manufacture programmable materials and reconfigurable robots for cooperative grasping, collective cargo transportation, and micro- and nanoengineering.

  12. Model documentation coal market module of the National Energy Modeling System

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-02-01

    This report documents the objectives and the conceptual and methodological approach used in the development of the Coal Production Submodule (CPS). It provides a description of the CPS for model analysts and the public. The Coal Market Module provides annual forecasts of prices, production, and consumption of coal.

  13. Fine specificity and cross-reactions of monoclonal antibodies to group B streptococcal capsular polysaccharide type III

    DEFF Research Database (Denmark)

    Pincus, Seth H; Moran, Emily; Maresh, Grace

    2012-01-01

    ) is considered the dominant "protective" immune mediator. Here we study the fine specificity and potential host reactivity of a panel of well-characterized murine monoclonal Abs against the type III CPS by examining the binding of the Abs to intact and neuraminidase-digested GBS, purified CPS, synthetic...

  14. Engagement and Action for Health: The Contribution of Leaders’ Collaborative Skills to Partnership Success

    Directory of Open Access Journals (Sweden)

    Walid El Ansari

    2009-01-01

    Full Text Available A multi-site evaluation (survey of five Kellogg-funded Community Partnerships (CPs in South Africa was undertaken to explore the relationship between leadership skills and a range of 30 operational, functional and organisational factors deemed critical to successful CPs. The CPs were collaborative academic-health service-community efforts aimed at health professions education reforms. The level of agreement to eleven dichotomous (‘Yes/No’ leadership skills items was used to compute two measures of members’ appreciation of their CPs’ leadership. The associations between these measures and 30 CPs factors were explored, and the partnership factors that leadership skills explained were assessed after controlling. Respondents who perceived the leadership of their CPs favourably had more positive ratings across 30 other artnership factors than those who rated leadership skills less favourably, and were more likely to report a positive cost/benefit ratio. In addition, respondents who viewed their CPs’ leadership positively also rated the operational understanding, the communication mechanisms, as well as the rules and procedures of the CPs more favourably. Leadership skills explained between 20% and 7% of the variance of 10 partnership factors. The influence of leaders’ skills in effective healthfocussed partnerships is much broader than previously conceptualised.

  15. A Simple Correctness Proof of the Direct-Style Transformation

    DEFF Research Database (Denmark)

    Nielsen, Lasse Riechstein

    2002-01-01

    -pass higher-order CPS transformation, and were complicated by having to reason about higher-order functions. In contrast, this work is based on a one-pass CPS transformation that is both compositional and first-order, and therefore the proof simply proceeds by structural induction on syntax....

  16. Child, Caregiver, and Family Characteristics Associated with Emergency Department Use by Children Who Remain at Home after a Child Protective Services Investigation

    Science.gov (United States)

    Schneiderman, Janet U.; Hurlburt, Michael S.; Leslie, Laurel K.; Zhang, Jinjin; Horwitz, Sarah McCue

    2012-01-01

    Objectives: To examine emergency department (ED) use among children involved with child protective services (CPS) in the US but who remain at home, and to determine if ED use is related to child, caregiver and family characteristics as well as receipt of CPS services. Method: We analyzed data on 4,001 children in the National Survey of Child and…

  17. Wearable and mobile systems

    NARCIS (Netherlands)

    Jozwiak, L.

    2016-01-01

    The recent spectacular progress in the microelectronic, information, communication, material and sensor technologies created a big stimulus towards development of smart communicating cyber-physical systems (CPS). CPS connected to Internet started to form the Internet of Things (IoT) that is

  18. The cryogenic pumping section of KATRIN and the test experiment TRAP

    CERN Document Server

    Eichelhardt, F

    2011-01-01

    The Karlsruhe Tritium Neutrino experiment (KATRIN) employs a Cryogenic Pumping Section (CPS) at ~ 4.5 K to suppress the tritium penetration into the spectrometers. A test experiment (TRAP - Tritium Argon frost Pump) has been set up to investigate the tritium pumping performance of the CPS.

  19. Enhancing Student Learning through Scaffolded Client Projects

    Science.gov (United States)

    Tomlinson, Elizabeth

    2017-01-01

    This article reports on the current status of client projects (CPs) in business communication courses, provides a scaffolded model for implementing CP, and assesses student learning in CPs. Using a longitudinal mixed method research design, survey data and qualitative materials from six semesters are presented. The instructor survey indicated need…

  20. The Effects of the Classroom Performance System on Student Participation, Attendance, and Achievement

    Science.gov (United States)

    Termos, Mohamad Hani

    2013-01-01

    The Classroom Performance System (CPS) is an instructional technology that increases student performance and promotes active learning. This study assessed the effect of the CPS on student participation, attendance, and achievement in multicultural college-level anatomy and physiology classes, where students' first spoken language is not English.…