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Sample records for adjusted ventilatory assist

  1. A prospective crossover comparison of neurally adjusted ventilatory assist and pressure-support ventilation in a pediatric and neonatal intensive care unit population.

    LENUS (Irish Health Repository)

    Breatnach, Cormac

    2012-02-01

    OBJECTIVE: To compare neurally adjusted ventilatory assist ventilation with pressure-support ventilation. DESIGN: Prospective, crossover comparison study. SETTING: Tertiary care pediatric and neonatal intensive care unit. PATIENTS: Sixteen ventilated infants and children: mean age = 9.7 months (range = 2 days-4 yrs) and mean weight = 6.2 kg (range = 2.4-13.7kg). INTERVENTIONS: A modified nasogastric tube was inserted and correct positioning was confirmed. Patients were ventilated in pressure-support mode with a pneumatic trigger for a 30-min period and then in neurally adjusted ventilatory assist mode for up to 4 hrs. MEASUREMENTS AND MAIN RESULTS: Data collected for comparison included activating trigger (neural vs. pneumatic), peak and mean airway pressures, expired minute and tidal volumes, heart rate, respiratory rate, pulse oximetry, end-tidal CO2 and arterial blood gases. Synchrony was improved in neurally adjusted ventilatory assist mode with 65% (+\\/-21%) of breaths triggered neurally vs. 35% pneumatically (p < .001) and 85% (+\\/-8%) of breaths cycled-off neurally vs. 15% pneumatically (p = .0001). The peak airway pressure in neurally adjusted ventilatory assist mode was significantly lower than in pressure-support mode with a 28% decrease in pressure after 30 mins (p = .003) and 32% decrease after 3 hrs (p < .001). Mean airway pressure was reduced by 11% at 30 mins (p = .13) and 9% at 3 hrs (p = .31) in neurally adjusted ventilatory assist mode although this did not reach statistical significance. Patient hemodynamics and gas exchange remained stable for the study period. No adverse patient events or device effects were noted. CONCLUSIONS: In a neonatal and pediatric intensive care unit population, ventilation in neurally adjusted ventilatory assist mode was associated with improved patient-ventilator synchrony and lower peak airway pressure when compared with pressure-support ventilation with a pneumatic trigger. Ventilating patients in this new mode

  2. A randomized clinical trial of neurally adjusted ventilatory assist versus conventional weaning mode in patients with COPD and prolonged mechanical ventilation

    Directory of Open Access Journals (Sweden)

    Kuo NY

    2016-05-01

    Full Text Available Nai-Ying Kuo,1,2 Mei-Lien Tu,1,3 Tsai-Yi Hung,1 Shih-Feng Liu,4 Yu-Hsiu Chung,4 Meng-Chih Lin,4 Chao-Chien Wu41Department of Respiratory Therapy, Kaohsiung Chang Gung Memorial Hospital; 2Kaohsiung Medical University; 3Respiratory Care, Chang Gung University of Science and Technology, Chiayi, Taiwan; 4Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, TaiwanBackground: Patient-ventilator asynchrony is a common problem in mechanically ventilated patients; the problem is especially obvious in COPD. Neutrally adjusted ventilatory assist (NAVA can improve patient-ventilator asynchrony; however, the effect in COPD patients with prolonged mechanical ventilation is still unknown. The goals of this study are to evaluate the effect of NAVA and conventional weaning mode in patients with COPD during prolonged mechanical ventilation.Methods: The study enrolled a total of 33 COPD patients with ventilator dependency for more than 21 days in the weaning center. A diaphragm electrical activity (Edi catheter was inserted in patients within 24 hours after admission to the respiratory care center, and patients were randomly allocated to NAVA or conventional group. A spontaneous breathing trial was performed every 24 hours. The results correlated with the clinical parameters.Results: There were significantly higher asynchrony incidence rates in the whole group after using Edi catheter (before vs post-Edi catheter insertion =60.6% vs 87.9%, P<0.001. Asynchrony index: before vs post-Edi catheter insertion =7.4%±8.5% vs 13.2%±13.5%, P<0.01. Asynchrony incidence: NAVA vs conventional =0% vs 84.2%, P<0.001. Asynchrony index: NAVA vs conventional =0 vs 11.9±11.2 (breath %, P<0.001. The most common asynchrony events were ineffective trigger and delayed trigger. Conclusion: Compared to conventional mode, NAVA mode can significantly enhance

  3. 75 FR 59681 - Trade Adjustment Assistance for Farmers

    Science.gov (United States)

    2010-09-28

    ... Foreign Agricultural Service Trade Adjustment Assistance for Farmers AGENCY: Foreign Agricultural Service... Farmers Program Review Committee, comprised of representatives from USDA's Office of the Chief Economist... adjustment assistance in FY 2011. FOR FURTHER INFORMATION CONTACT: Trade Adjustment Assistance for...

  4. 75 FR 59683 - Trade Adjustment Assistance for Farmers

    Science.gov (United States)

    2010-09-28

    ... Foreign Agricultural Service Trade Adjustment Assistance for Farmers AGENCY: Foreign Agricultural Service... for Farmers Program Review Committee, comprised of representatives from USDA's Office of the Chief... assistance in FY 2011. FOR FURTHER INFORMATION, CONTACT: Trade Adjustment Assistance for Farmers...

  5. 75 FR 59685 - Trade Adjustment Assistance for Farmers

    Science.gov (United States)

    2010-09-28

    ... Foreign Agricultural Service Trade Adjustment Assistance for Farmers AGENCY: Foreign Agricultural Service... analyzed by USDA's Economic Research Service and reviewed by the Trade Adjustment Assistance for Farmers... assistance in FY 2011. FOR FURTHER INFORMATION CONTACT: Trade Adjustment Assistance for Farmers Program...

  6. 75 FR 23667 - Trade Adjustment Assistance for Farmers

    Science.gov (United States)

    2010-05-04

    ... From the Federal Register Online via the Government Publishing Office ] DEPARTMENT OF AGRICULTURE Foreign Agricultural Service Trade Adjustment Assistance for Farmers AGENCY: Foreign Agricultural Service... site for the Trade Adjustment Assistance for Farmers program. The URL is...

  7. 75 FR 63437 - Trade Adjustment Assistance for Farmers

    Science.gov (United States)

    2010-10-15

    ... Foreign Agricultural Service Trade Adjustment Assistance for Farmers AGENCY: Foreign Agricultural Service... Farmers Program Review Committee, comprised of representatives from USDA's Office of the Chief Economist... CONTACT: Trade Adjustment Assistance for Farmers Program Staff, Office of Trade Programs, FAS, USDA,...

  8. 75 FR 59682 - Trade Adjustment Assistance for Farmers

    Science.gov (United States)

    2010-09-28

    ... Foreign Agricultural Service Trade Adjustment Assistance for Farmers AGENCY: Foreign Agricultural Service... analyzed by USDA's Economic Research Service and reviewed by the Trade Adjustment Assistance for Farmers... Adjustment Assistance for Farmers Program Staff, Office of Trade Programs, FAS, USDA, or by phone at...

  9. 75 FR 43140 - Trade Adjustment Assistance for Farmers

    Science.gov (United States)

    2010-07-23

    ... Foreign Agricultural Service Trade Adjustment Assistance for Farmers AGENCY: Foreign Agricultural Service... assistance and cash benefits. FOR FURTHER INFORMATION CONTACT: Trade Adjustment Assistance for Farmers Staff... ; or visit the TAA for Farmers' Web site: http://www.fas.usda.gov/itp/taa . Dated: July 14, 2010....

  10. 75 FR 45092 - Trade Adjustment Assistance for Farmers

    Science.gov (United States)

    2010-08-02

    ... Foreign Agricultural Service Trade Adjustment Assistance for Farmers AGENCY: Foreign Agricultural Service.... FOR FURTHER INFORMATION CONTACT: Trade Adjustment Assistance for Farmers Program Staff, FAS, USDA by... TAA for Farmers' Web site: http://www.fas.usda.gov/itp/taa . Dated: July 21, 2010. John D....

  11. 75 FR 48931 - Trade Adjustment Assistance for Farmers

    Science.gov (United States)

    2010-08-12

    ... Foreign Agricultural Service Trade Adjustment Assistance for Farmers AGENCY: Foreign Agricultural Service... FURTHER INFORMATION CONTACT: Trade Adjustment Assistance for Farmers Program Staff, FAS, USDA by phone... Farmers' Web site: www.fas.usda.gov/itp/taa . Dated: July 30, 2010. John D. Brewer, Administrator,...

  12. 75 FR 43485 - Trade Adjustment Assistance for Farmers

    Science.gov (United States)

    2010-07-26

    ...; ] DEPARTMENT OF AGRICULTURE Foreign Agricultural Service Trade Adjustment Assistance for Farmers AGENCY...: Trade Adjustment Assistance for Farmers Staff, FAS, USDA, by phone: (202) 720-0638, or (202) 690-0633; or by e-mail: tradeadjustment@fas.usda.gov ; or visit the TAA for Farmers' Web site:...

  13. 75 FR 49458 - Trade Adjustment Assistance for Farmers

    Science.gov (United States)

    2010-08-13

    ... Foreign Agricultural Service Trade Adjustment Assistance for Farmers AGENCY: Foreign Agricultural Service.... FOR FURTHER INFORMATION CONTACT: Trade Adjustment Assistance for Farmers Program Staff, FAS, USDA by... TAA for Farmers' Web site: http://www.fas.usda.gov/itp/taa . Dated: August 3, 2010. Suzanne...

  14. 75 FR 49886 - Trade Adjustment Assistance for Farmers

    Science.gov (United States)

    2010-08-16

    ... Foreign Agricultural Service Trade Adjustment Assistance for Farmers AGENCY: Foreign Agricultural Service... CONTACT: Trade Adjustment Assistance for Farmers Program Staff, FAS, USDA by phone: (202) 720-0638 or (202) 690- 0633; or by e-mail at: tradeadjustment@fas.usda.gov ; or visit ] the TAA for Farmers' Web...

  15. 75 FR 48642 - Trade Adjustment Assistance for Farmers

    Science.gov (United States)

    2010-08-11

    ... Foreign Agricultural Service Trade Adjustment Assistance for Farmers AGENCY: Foreign Agricultural Service... Adjustment Assistance for Farmers Program Staff, FAS, USDA by phone: (202) 720-0638 or (202) 690- 0633; or by e-mail at: tradeadjustment@fas.usda.gov ; or visit the TAA for Farmers' Web site:...

  16. Metabolic acidosis and ventilatory response

    NARCIS (Netherlands)

    Langbroek, Aart Jan Mattheüs

    1988-01-01

    In terrestrial vertebrates lung ventilation is nescessary to accmplish exchange of oxygen (O2) and carbon dioxide (CO2) between the gas phase (lung alveoli) and the fluid phase (the blood flowing through the lung capillaries). The ventilatory control system adjusts the arterial carbon dioxide tensio

  17. 75 FR 41432 - Trade Adjustment Assistance for Farmers

    Science.gov (United States)

    2010-07-16

    ... Foreign Agricultural Service Trade Adjustment Assistance for Farmers AGENCY: Foreign Agricultural Service... Farmers Review Committee, comprised of representatives from USDA's Office of the Chief Economist, Farm... Farmers' Program Should Contact: USDA, Farm Service Agency (at your local service center). FOR...

  18. 75 FR 41433 - Trade Adjustment Assistance for Farmers

    Science.gov (United States)

    2010-07-16

    ... Foreign Agricultural Service Trade Adjustment Assistance for Farmers AGENCY: Foreign Agricultural Service... TAA for Farmers Review Committee, comprised of representatives from USDA's Office of the Chief... eligible for cash benefits. Producers Certified as Eligible For TAA for Farmers' Program Should...

  19. 75 FR 41431 - Trade Adjustment Assistance for Farmers

    Science.gov (United States)

    2010-07-16

    ... Foreign Agricultural Service Trade Adjustment Assistance for Farmers AGENCY: Foreign Agricultural Service... Economic Research Service and reviewed by the TAA for Farmers Review Committee, comprised of... Assistance for Farmers Staff, FAS, USDA, by phone: (202) 720-0638, or (202) 690-0633; or by...

  20. 75 FR 42375 - Trade Adjustment Assistance for Farmers

    Science.gov (United States)

    2010-07-21

    ... Foreign Agricultural Service Trade Adjustment Assistance for Farmers AGENCY: Foreign Agricultural Service... Assistance for Farmers Staff, FAS, USDA, by phone: (202) 720-0638, or (202) 690-0633; or by e-mail: tradeadjustment@fas.usda.gov ; or visit the TAA for Farmers' Web site: http://www.fas.usda.gov/itp/taa ....

  1. 75 FR 41430 - Trade Adjustment Assistance for Farmers

    Science.gov (United States)

    2010-07-16

    ...; ] DEPARTMENT OF AGRICULTURE Foreign Agricultural Service Trade Adjustment Assistance for Farmers AGENCY... Economic Research Service and reviewed by the TAA for Farmers Review Committee, comprised of... Assistance for Farmers Staff, FAS, USDA, by phone: (202) 720-0638, or (202) 690-0633; or by...

  2. 75 FR 59683 - Trade Adjustment Assistance for Farmers

    Science.gov (United States)

    2010-09-28

    ... (No. 2011020) for trade adjustment assistance for coffee filed under the fiscal year (FY) 2011 program by the Kona Coffee Farmers Association. The petition was accepted for review by USDA on July 21, 2010... following factors: national average price, quantity of production, value of production, or cash...

  3. 75 FR 59684 - Trade Adjustment Assistance for Farmers

    Science.gov (United States)

    2010-09-28

    ... (No. 2011001) for trade adjustment assistance for coffee filed under the fiscal year (FY) 2011 program by 100% Puerto Rico Coffee Export Board, Inc. The petition was accepted for review by USDA on July 21... one of the following factors: national average price, quantity of production, value of production,...

  4. 75 FR 61121 - Trade Adjustment Assistance for Farmers

    Science.gov (United States)

    2010-10-04

    ... Foreign Agricultural Service Trade Adjustment Assistance for Farmers AGENCY: Foreign Agricultural Service... Economic Research Service and reviewed by the TAA for Farmers Program Review Committee, comprised of... program in order to be eligible for cash benefits. Producers Certified As Eligible For TAA For...

  5. 75 FR 62760 - Trade Adjustment Assistance for Farmers

    Science.gov (United States)

    2010-10-13

    ... Foreign Agricultural Service Trade Adjustment Assistance for Farmers AGENCY: Foreign Agricultural Service... analyzed by USDA's Economic Research Service and reviewed by the TAA for Farmers Program Review Committee... CERTIFIED AS ELIGIBLE FOR TAA FOR FARMERS CONTACT: Your local USDA Farm Service Agency county office....

  6. 75 FR 41434 - Trade Adjustment Assistance for Farmers

    Science.gov (United States)

    2010-07-16

    ... Foreign Agricultural Service Trade Adjustment Assistance for Farmers AGENCY: Foreign Agricultural Service... Crawfish Farmers Association and accepted for review by USDA on May 3, 2010. SUPPLEMENTARY INFORMATION: To... and reviewed by the TAA for Farmers Review Committee, comprised of representatives from USDA's...

  7. Ventilatory chaos is impaired in carotid atherosclerosis.

    Directory of Open Access Journals (Sweden)

    Laurence Mangin

    Full Text Available Ventilatory chaos is strongly linked to the activity of central pattern generators, alone or influenced by respiratory or cardiovascular afferents. We hypothesized that carotid atherosclerosis should alter ventilatory chaos through baroreflex and autonomic nervous system dysfunctions. Chaotic dynamics of inspiratory flow was prospectively evaluated in 75 subjects undergoing carotid ultrasonography: 27 with severe carotid stenosis (>70%, 23 with moderate stenosis (<70%, and 25 controls. Chaos was characterized by the noise titration method, the correlation dimension and the largest Lyapunov exponent. Baroreflex sensitivity was estimated in the frequency domain. In the control group, 92% of the time series exhibit nonlinear deterministic chaos with positive noise limit, whereas only 68% had a positive noise limit value in the stenoses groups. Ventilatory chaos was impaired in the groups with carotid stenoses, with significant parallel decrease in the noise limit value, correlation dimension and largest Lyapunov exponent, as compared to controls. In multiple regression models, the percentage of carotid stenosis was the best in predicting the correlation dimension (p<0.001, adjusted R(2: 0.35 and largest Lyapunov exponent (p<0.001, adjusted R(2: 0.6. Baroreflex sensitivity also predicted the correlation dimension values (p = 0.05, and the LLE (p = 0.08. Plaque removal after carotid surgery reversed the loss of ventilatory complexity. To conclude, ventilatory chaos is impaired in carotid atherosclerosis. These findings depend on the severity of the stenosis, its localization, plaque surface and morphology features, and is independently associated with baroreflex sensitivity reduction. These findings should help to understand the determinants of ventilatory complexity and breathing control in pathological conditions.

  8. 24 CFR 1000.320 - How is Formula Current Assisted Stock adjusted for local area costs?

    Science.gov (United States)

    2010-04-01

    ... § 1000.320 How is Formula Current Assisted Stock adjusted for local area costs? There are two adjustment... 24 Housing and Urban Development 4 2010-04-01 2010-04-01 false How is Formula Current Assisted Stock adjusted for local area costs? 1000.320 Section 1000.320 Housing and Urban Development...

  9. 77 FR 23288 - Notice of Determinations Regarding Eligibility To Apply for Worker Adjustment Assistance

    Science.gov (United States)

    2012-04-18

    ... March 14, 2011. Scientific Milwaukee, LLC, Molecular Biology Reagents Division. 81,426 Dixtal Medical..., Emporia, VA March 13, 2011. Campbell Foundry. Negative Determinations for Worker Adjustment Assistance...

  10. 7 CFR 4279.175 - Domestic lamb industry adjustment assistance program set aside.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 15 2010-01-01 2010-01-01 false Domestic lamb industry adjustment assistance program... GUARANTEED LOANMAKING Business and Industry Loans § 4279.175 Domestic lamb industry adjustment assistance... National Office to fund loans to lamb processors for real estate purchases and improvements;...

  11. 38 CFR 36.4412 - Annual adjustments to the aggregate amount of assistance available.

    Science.gov (United States)

    2010-07-01

    ... 38 Pensions, Bonuses, and Veterans' Relief 2 2010-07-01 2010-07-01 false Annual adjustments to the aggregate amount of assistance available. 36.4412 Section 36.4412 Pensions, Bonuses, and Veterans' Relief... Specially Adapted Housing § 36.4412 Annual adjustments to the aggregate amount of assistance available....

  12. 75 FR 23227 - Trade Adjustment Assistance for Farmers

    Science.gov (United States)

    2010-05-03

    ... lilies contributed importantly to a greater than 15 percent decrease in cash receipts for lilies compared... apply to the Farm Service Agency for technical assistance at no cost and cash benefits. FOR...

  13. 78 FR 61395 - Investigations Regarding Eligibility To Apply for Worker Adjustment Assistance

    Science.gov (United States)

    2013-10-03

    ... 12th day of September 2013. Michael W. Jaffe, Certifying Officer, Office of Trade Adjustment Assistance... Blueshield), PSSCR (State/ One-Stop). 83043 Volcano Corporation (State/ Rancho Cordova, CA.... 08/30/13...

  14. 75 FR 7039 - Investigations Regarding Certifications of Eligibility to Apply for Worker Adjustment Assistance

    Science.gov (United States)

    2010-02-16

    ... adjustment assistance under Title II, Chapter 2, of the Act. The investigations will further relate, as......... 01/13/10 11/01/09 73267 Johnston Supply, Inc. Ashland, OH 01/13/10 12/31/09 (Comp). 73268...

  15. 75 FR 28780 - Trade Adjustment Assistance for Farmers

    Science.gov (United States)

    2010-05-24

    ... in the national average price, or quantity of production, or value of production, or cash receipts... production, or cash receipts for the agricultural commodity specified in the petition, compared to the... Agriculture (USDA) provides technical assistance and cash benefits to eligible producers of raw...

  16. 75 FR 11513 - Trade Adjustment Assistance for Farmers

    Science.gov (United States)

    2010-03-11

    ... value of production, or cash receipts for the commodity specified in the petition compared to the... the national average price, or quantity of production, or value of production, or cash receipts for.... Under this program, the U.S. Department of Agriculture (USDA) provides technical assistance and...

  17. 75 FR 51978 - Trade Adjustment Assistance for Farmers

    Science.gov (United States)

    2010-08-24

    ... decrease in the average annual price of tilapia, quantity of production, value of production, or cash receipts, compared to the average of the three preceding marketing years. If a determination is affirmative... for free technical assistance and cash benefits. FOR FURTHER INFORMATION CONTACT: Trade...

  18. European Globalisation Adjustment Fund-Assistance in the Labour Market

    Directory of Open Access Journals (Sweden)

    Ramona Mariana CALINICA

    2016-12-01

    Full Text Available The intensification of globalization and through intense manifestation of the effects on recent economic and financial crisis, employment market has been affected, and at European Union level was considered increasingly necessary granting support for counter of the negative effects of the two phenomena on this market. European Globalisation Adjustment Fund is designed for a rapid reintegration of fired workers and increase of the employment potential of the workforce, after mass dismissals linked to the two phenomena mentioned above.

  19. 77 FR 77217 - Fiscal Year 2012 Annual Report to Congress on the Trade Adjustment Assistance for Firms Program

    Science.gov (United States)

    2012-12-31

    ... firm eligibility--provided under the Trade and Globalization Adjustment Assistance Act of 2009 (TGAAA... firm's strengths and weaknesses and develop a customized business strategy (AP) designed to...

  20. 77 FR 28901 - Amended Certification Regarding Eligibility To Apply for Worker Adjustment Assistance; Lexis...

    Science.gov (United States)

    2012-05-16

    ... Adjustment Assistance; Lexis Nexis, a Subsidiary of Reed Elsevier, Quality & Metrics Department, Including... Reed Elsevier, Quality & Metrics Department, Including Employees Located Throughout the United States... report wages under the parent company, Reed Elsevier. The amended notice applicable to TA-W-80,205 and...

  1. 78 FR 28636 - Notice of Determinations Regarding Eligibility To Apply for Worker Adjustment Assistance

    Science.gov (United States)

    2013-05-15

    ... Trade Commission as a member of a domestic industry in an investigation resulting in-- (A) An... Management, Global Tech, Citi Shared, Leased Workers. 82,558 Abbott Diabetes Care, Abbott, Langhorne, PA... for Worker Adjustment Assistance In the following cases, the investigation revealed that...

  2. 78 FR 780 - Investigations Regarding Certifications of Eligibility To Apply for Worker Adjustment Assistance

    Science.gov (United States)

    2013-01-04

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF LABOR... adjustment assistance under Title II, Chapter 2, of the Act. The investigations will further relate, as...). 82175 Philips Healthcare (Workers) Highland Heights, OH... 11/27/12 11/16/12 82176 RockTenn...

  3. 75 FR 49533 - Investigations Regarding Certifications of Eligibility To Apply for Worker Adjustment Assistance

    Science.gov (United States)

    2010-08-13

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF LABOR... adjustment assistance under Title II, Chapter 2, of the Act. The investigations will further relate, as.../10 LLC (State/One-Stop). MI. 74435 Philips Lighting Union, NJ......... 07/28/10 07/21/10...

  4. 78 FR 48471 - Investigations Regarding Eligibility To Apply for Worker Adjustment Assistance

    Science.gov (United States)

    2013-08-08

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF LABOR... to determine whether the workers are eligible to apply for adjustment assistance under Title II...). Jonesboro, AR......... 07/05/13 07/03/13 82876 Philips Respironics (State/ Wallingford, CT..........

  5. 77 FR 29366 - Investigations Regarding Eligibility To Apply for Worker Adjustment Assistance

    Science.gov (United States)

    2012-05-17

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF LABOR... to determine whether the workers are eligible to apply for adjustment assistance under Title II... (Company). 81526 Philips Healthcare/ Murrysville, PA....... 04/23/12 03/15/12 Respironics (Workers)....

  6. 78 FR 69883 - Investigations Regarding Eligibility To Apply for Worker Adjustment Assistance

    Science.gov (United States)

    2013-11-21

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF LABOR... to determine whether the workers are eligible to apply for adjustment assistance under Title II...). 83163 Osram Sylvania (State/One- Luquillo, PR 10/22/13 10/21/13 Stop). 83164 Philips Lumileds...

  7. 78 FR 781 - Investigations Regarding Eligibility To Apply for Worker Adjustment Assistance

    Science.gov (United States)

    2013-01-04

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF LABOR... to determine whether the workers are eligible to apply for adjustment assistance under Title II... International, Buena Park, CA......... 12/12/12 12/11/12 Esterline Corporation (Company). 82244 Philips...

  8. 75 FR 68623 - Investigations Regarding Certifications of Eligibility To Apply for Worker Adjustment Assistance

    Science.gov (United States)

    2010-11-08

    ... substantial interest in the subject matter of the investigations may request a public hearing, provided such... regarding the subject matter of the investigations to the Director, Division of Trade Adjustment Assistance... Antenna Systems, Albion, MI 10/22/10 10/18/10 Inc. (Company). 74766 Rocon Manufacturing Rochester,...

  9. 24 CFR 570.401 - Community adjustment and economic diversification planning assistance.

    Science.gov (United States)

    2010-04-01

    ... 24 Housing and Urban Development 3 2010-04-01 2010-04-01 false Community adjustment and economic... Housing and Urban Development (Continued) OFFICE OF ASSISTANT SECRETARY FOR COMMUNITY PLANNING AND DEVELOPMENT, DEPARTMENT OF HOUSING AND URBAN DEVELOPMENT COMMUNITY FACILITIES COMMUNITY DEVELOPMENT...

  10. 78 FR 3031 - Amended Certification Regarding Eligibility To Apply for Worker Adjustment Assistance

    Science.gov (United States)

    2013-01-15

    ... Adjustment Assistance TA-W-81,739, HEWLETT-PACKARD COMPANY, PERSONAL PRINTING SYSTEMS (PPS), FORMERLY KNOWN... PRINTING SYSTEMS (PPS), INK JET & WEB SERVICES (IWS), WORLD WIDE DESIGN GROUP, VANCOUVER, WA; TA-W-81,739B, HEWLETT-PACKARD COMPANY, PERSONAL PRINTING SYSTEMS (PPS), SUPPLY CHAIN OPERATIONS (FORMERLY KNOWN AS...

  11. 75 FR 6688 - Section 8 Housing Assistance Payments Program-Renewal Funding Annual Adjustment Factors, Fiscal...

    Science.gov (United States)

    2010-02-10

    ... URBAN DEVELOPMENT Section 8 Housing Assistance Payments Program--Renewal Funding Annual Adjustment... Agency (PHA) based on Voucher Management System (VMS) leasing and cost data for the most recent Federal... circumstances most relevant to the Housing Choice Voucher (HCV) program in 2010 and the assumptions of the...

  12. 75 FR 7041 - Investigations Regarding Certifications of Eligibility To Apply for Worker Adjustment Assistance

    Science.gov (United States)

    2010-02-16

    ... Trade Adjustment Assistance. Appendix Subject firm Date of Date of TA-W (petitioners) Location.... North Wilkesboro, NC... 01/21/10 01/08/10 (Comp). 73320 Rio Tinto Services, Inc. South Jordan, UT... Elkins, WV 01/22/10 01/21/10 Group (Comp). 73334 GBR Systems Ltd (State). Chester, CT 01/22/10...

  13. 75 FR 2491 - Trade Adjustment Assistance for Firms Program Fiscal Year 2009 Annual Report

    Science.gov (United States)

    2010-01-15

    ... Adjustment Assistance Centers' goal is to help U.S. firms increase profitability and retain employees while.../customer diversification server improvement bar coding brand recognition/ CRM and PM software financial... customer communication government procurement enhance testing and marketing/advertising tools...

  14. 76 FR 5811 - Adjusted Federal Medical Assistance Percentage (FMAP) Rate for the First Quarter of Fiscal Year...

    Science.gov (United States)

    2011-02-02

    ... HUMAN SERVICES Adjusted Federal Medical Assistance Percentage (FMAP) Rate for the First Quarter of... 2009 (Pub. L. 111-5) for Adjustments to the First Quarter of Fiscal Year 2011 Federal Medical... quarter of Fiscal Year 2011 (FY11) as required under Section 5001 of the American Recovery...

  15. Psychological stress and adjustment in pregnancy following assisted reproductive technology and spontaneous conception: A systematic review.

    Science.gov (United States)

    Gourounti, Kleanthi

    2016-01-01

    The aim of this review was to examine studies describing the psychological stress and adjustment in pregnancy after an assisted reproductive technology (ART) treatment. A systematic search of the electronic databases was performed. This review considered only quantitative, primary studies in the English language, published during the period 2000-2014 and relevant to the objective. The population of interest was previously infertile pregnant women. Outcome variables were general anxiety, depressive symptoms, pregnancy-specific anxiety, quality of life, self-esteem, pregnancy attitudes and adjustment, and maternal-fetal attachment. Twenty studies met the inclusion and methodological criteria and were included in the review. The review revealed that compared to women who conceive naturally or to general norms, women who conceive after an in vitro fertilization treatment had greater pregnancy-specific anxiety, poorer quality of life, either the same or less depressive symptomatology, the same level of self-esteem, more positive attitudes toward pregnancy demands, and higher levels of maternal-fetal attachment. However, the evidence regarding the general anxiety levels in pregnancy after an ART treatment was inconclusive. Methodological limitations and differences across studies may explain the inconsistencies in their findings regarding the impact of ART. This review provides an insight into psychological reactions and adjustment in pregnancy after an ART treatment.

  16. Leg strength is associated with ventilatory efficiency in older women.

    Science.gov (United States)

    Gonzales, J U; Tucker, S H; Kalasky, M J; Proctor, D N

    2012-07-01

    The aim of the present study was to determine if leg function is associated with ventilatory efficiency during exercise in healthy older adults. 24 women and 18 men aged 60-80 years performed treadmill exercise to fatigue for calculation of ventilatory efficiency using the ratio of ventilation to carbon dioxide at the anaerobic threshold (VE/VCO₂@AT). On a separate day, participants performed leg strength testing and graded single-leg knee extension exercise. The VE/VCO₂@AT was higher in women than men (33±3 vs. 30±3; p=0.03). After adjustment for age and VO(₂max), leg strength (knee extensor isometric force) was inversely associated with VE/VCO₂@AT in women (r= - 0.44, p=0.03) while no relationships were found for men. Strength-matched women and men had similar VE/VCO₂@AT indicating that the correlation between leg strength and VE/VCO₂@AT was strength- but not sex-specific. During knee extensor exercise, women with lower leg strength had increased VE/VCO₂ slope across 0-15 W as compared to higher strength women (38±8 vs. 31±3; p<0.05), while no differences were found for men. These results find leg strength to be associated with ventilatory responses to exercise in healthy older women, a finding that might be related to lower leg strength in women than men.

  17. Evaluation of ventilatory therapy for acid aspiration.

    Science.gov (United States)

    Flint, L; Gosdin, G; Carrico, C J

    1975-10-01

    Aspiration of hydrochloric acid in experimental animals results in severe, progressive hypoxia which is due to intrapulmonary shunting and depressed cardiac output. This preparation is useful therefore in studying the therapy of hypoxia. Mongrel dogs were subjected to acid aspiration and the effects of several ventilatory patterns on intrapulmonary shunt fractions and lung water accumulation observed. The combination of large tidal volumes (30 c.c. per kilogram) with positive end-expiratory pressure was effective in preventing intrapulmonary shunting and other ventilatory patterns were ineffective. Pulmonary edema uniformly followed acid aspiration and was not affected by ventilatory therapy. When ventilatory therapy was delayed for 4 hours, the progression of shunting apparently was limited, but the existing shunt was not reduced.

  18. Home mechanical ventilatory support in patients with restrictive ventilatory disorders : A 48-year experience

    NARCIS (Netherlands)

    Duiverman, ML; Bladder, G; Meinesz, AF; Wijkstra, PJ

    2006-01-01

    We performed a retrospective analysis to the effects of negative pressure ventilation (NPV), tracheal intermittent positive pressure ventilation (TIPPV), and nasal intermittent positive pressure ventilation (NIPPV, volume or pressure-controlled ventilatory mode), in 114 patients with restrictive ven

  19. Measurement of ventilatory threshold by respiratory frequency.

    Science.gov (United States)

    Nabetani, Teru; Ueda, Takeshi; Teramoto, Keisuke

    2002-06-01

    This study was conducted to assess whether respiratory frequency can be used as a valid parameter for estimating ventilatory threshold and for examining differences in exercise modes such as a cycle ergometer and a treadmill. 24 men and 12 women performed an incremental exercise test to exhaustion on a cycle ergometer and on a treadmill. Oxygen uptake, carbon dioxide output, pulmonary ventilation, ventilatory frequency, and heart rate were measured continuously every 30 sec. during the test. Three different and independent reviewers detected the ventilatory threshold point and break point of respiratory rate, which were then compared. Analysis indicated that (1) ventilatory threshold was well correlated with break point of respiratory rate for both cycle (r=.88, pcycle) or 88% (treadmill) of break point of respiratory rate. (2) The regression equation for treadmill exercise was more accurate than that for cycling, but the detected data samples were smaller. The break point of respiratory rate was more easily detected for the cycle ergometer test 33 of 36 subjects) than for the treadmill test (only 15 of 36). The cycle ergometer test identified the break point of respiratory rate more easily than did the treadmill test. (3) There was an association between physical fitness and whether the break point of respiratory rate was detectable, and the more fit the subject (above average), the more likely the break point was to be undetected. Our study demonstrates that the break point of respiratory rate is closely associated with ventilatory threshold and that the cycle ergometer test is more conducive than the treadmill test to the detectability of break point of respiratory rate.

  20. An Illustration to Assist in Comparing and Remembering Several Multiplicity Adjustment Methods

    Science.gov (United States)

    Hasler, Mario

    2017-01-01

    There are many well-known or new methods to adjust statistical tests for multiplicity. This article provides an illustration helping lecturers or consultants to remember the differences of three important multiplicity adjustment methods and to explain them to non-statisticians.

  1. 13 CFR 307.2 - Criteria for Economic Adjustment Assistance Investments.

    Science.gov (United States)

    2010-01-01

    ... Assistance Investments. 307.2 Section 307.2 Business Credit and Assistance ECONOMIC DEVELOPMENT... targeted economic sectors through use of tools that: (1) Help develop and implement a CEDS; (2) Expand the capacity of public officials and economic development organizations to work effectively with businesses;...

  2. 75 FR 6685 - Section 8 Housing Assistance Payments Program-Contract Rent Annual Adjustment Factors, Fiscal...

    Science.gov (United States)

    2010-02-10

    ... exceed the rent for a comparable unassisted unit of similar quality, type and age in the market area. 42... movers in unassisted market. Since HUD pays the full amount of any rent increases for assisted tenants... discount.' Turnover is lower in assisted properties than in the unassisted market, so the effect of...

  3. 76 FR 14421 - Section 8 Housing Assistance Payments Program-Contract Rent Annual Adjustment Factors (AAFs...

    Science.gov (United States)

    2011-03-16

    ... rent for a comparable unassisted unit of similar quality, type and age in the market area. 42 U.S.C... the unassisted market. Since HUD pays the full amount of any rent increases for assisted tenants... discount.'' Turnover is lower in assisted properties than in the unassisted market, so the effect of...

  4. 78 FR 61396 - Investigations Regarding Eligibility To Apply for Worker Adjustment Assistance

    Science.gov (United States)

    2013-10-03

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF LABOR Employment and Training Administration Investigations Regarding Eligibility To Apply for Worker Adjustment... International Banking Center (State/One-Stop). ] BILLING CODE 4510-FN-P...

  5. 75 FR 57514 - Notice of Determinations Regarding Eligibility To Apply for Worker Adjustment Assistance

    Science.gov (United States)

    2010-09-21

    ... Worker from Express Personnel Services, etc. 74,550 Artisans, Inc Glen Flora, WI...... August 20, 2009...,246 Bank of America, Card State College, PA... Customer Assistance Division. 74,290 Supermedia...

  6. Ventilatory efficiency during exercise in healthy subjects.

    Science.gov (United States)

    Sun, Xing-Guo; Hansen, James E; Garatachea, Nuria; Storer, Thomas W; Wasserman, Karlman

    2002-12-01

    When evaluating dyspnea in patients with heart or lung disease it is useful to measure the quantity of ventilation needed to eliminate metabolically produced CO2 (i.e., the ventilatory efficiency). Mathematically, the relationship between ventilation (VE) and CO2 output is determined by the arterial CO2 pressure and the physiologic dead space-tidal volume ratio. We decided to determine how age, sex, size, fitness, and the type of ergometer influenced ventilatory efficiency in normal subjects. Three methods were compared for expressing this relationship: (1) the VE versus CO2 output slope below the ventilatory compensation point, commonly used by cardiologists for estimating the severity of heart failure; (2) the VE/CO2 output ratio at the anaerobic threshold, commonly used by pulmonologists; and (3) the lowest VE/CO2 output ratio during exercise, the latter parameter not previously reported. We studied 474 healthy adults, between 17 and 78 years of age during incremental cycle and treadmill cardiopulmonary exercise tests at three test sites, correcting the total VE for the equipment dead space. The lowest VE/CO2 output ratio was insignificantly different from the ratio at the anaerobic threshold, less variable than that for the slope relationship, and unaffected by the site, ergometer, and gas exchange measurement systems. The regression equation for the lowest VE/CO2 output ratio was 27.94 + 0.108 x age + (0.97 = F, 0.0 = M) - 0.0376 x height, where age is in years and height is in centimeters. We conclude that the lowest VE/CO2 output ratio is the preferred noninvasive method to estimate ventilatory inefficiency.

  7. 78 FR 66783 - Investigations Regarding Eligibility To Apply for Worker Adjustment Assistance

    Science.gov (United States)

    2013-11-06

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF LABOR Employment and Training Administration Investigations Regarding Eligibility To Apply for Worker Adjustment.../13 (Workers). 83130 Harte Hanks Shoppers Inc. Brea, CA 10/17/13 09/30/13 (State/One-Stop)....

  8. When Parents Divorce: Assisting Teens to Adjust through a Group Approach.

    Science.gov (United States)

    Studer, Jeannine R.; Allton, Judith A.

    1996-01-01

    Addresses factors that contribute to the adjustment difficulties of children and adolescents when their parents divorce. Gender issues, custody, age, parenting style, visitation patterns, socioeconomic considerations, the support system, family size, and the reconstituted family are all discussed. Describes a model for an effective support group…

  9. 76 FR 13231 - Notice of Determinations Regarding Eligibility To Apply for Worker Adjustment Assistance

    Science.gov (United States)

    2011-03-10

    ... investigation resulting in-- (A) An affirmative determination of serious injury or threat thereof under section... Loom; Leased Workers Spherion. 74,902 Abbott Diabetes Care, Inc., Alameda, CA November 18, 2009. Leased... Assistance In the following cases, the investigation revealed that the eligibility criteria for...

  10. 76 FR 4730 - Notice of Determinations Regarding Eligibility To Apply for Worker Adjustment Assistance

    Science.gov (United States)

    2011-01-26

    ... the report submitted to the President by the International Trade Commission under section 202(f)(1... Assistance In the following cases, the investigation revealed that the eligibility criteria for worker...Drive Systems, Ogdensburg, NY Inc., TTI Turner Technology Instruments, Inc.; Leased Workers...

  11. 77 FR 22340 - Section 8 Housing Assistance Payments Program-Annual Adjustment Factors, Fiscal Year 2012

    Science.gov (United States)

    2012-04-13

    ... Statistics Consumer Price Index (CPI) survey. These factors are applied at Housing Assistance Payment (HAP... no need to differentiate the AAF by use. A separate Federal Register Notice will be published that.... There are three categories of Section 8 programs that use the AAFs: Category 1--The Section 8...

  12. 78 FR 30322 - Section 8 Housing Assistance Payments Program-Annual Adjustment Factors, Fiscal Year 2013

    Science.gov (United States)

    2013-05-22

    ... Statistics Consumer Price Index (CPI) survey. These factors are applied at Housing Assistance Payment (HAP... there is no need to differentiate the AAF by use. A separate Federal Register Notice will be published... program. There are three categories of Section 8 programs that use the AAFs: Category 1: The Section 8...

  13. Long-term survival rates of gravity-assisted, adjustable differential pressure valves in infants with hydrocephalus.

    Science.gov (United States)

    Gebert, Anna-Felicitas; Schulz, Matthias; Schwarz, Karin; Thomale, Ulrich-Wilhelm

    2016-05-01

    OBJECTIVE The use of adjustable differential pressure valves with gravity-assisted units in shunt therapy of children with hydrocephalus was reported to be feasible and promising as a way to avoid chronic overdrainage. In this single-center study, the authors' experiences in infants, who have higher rates of shunt complications, are presented. METHODS All data were collected from a cohort of infants (93 patients [37 girls and 56 boys], less than 1 year of age [mean age 4.1 ± 3.1 months]) who received their first adjustable pressure hydrocephalus shunt as either a primary or secondary implant between May 2007 and April 2012. Rates of valve and shunt failure were recorded for a total of 85 months until the end of the observation period in May 2014. RESULTS During a follow-up of 54.2 ± 15.9 months (range 26-85 months), the Kaplan-Meier rate of shunt survival was 69.2% at 1 year and 34.1% at 85 months; the Kaplan-Meier rate of valve survival was 77.8% at 1 year and 56% at 85 months. Survival rates of the shunt were significantly inferior if the patients had previous shunt surgery. During follow-up, 44 valves were exchanged in cases of infection (n = 19), occlusion (n = 14), dysfunction of the adjustment unit (n = 10), or to change the gravitational unit (n = 1). CONCLUSIONS Although a higher shunt complication rate is observed in infant populations compared with older children, reasonable survival rates demonstrate the feasibility of using this sophisticated valve technology. The gravitational unit of this valve is well tolerated and its adjustability offers the flexible application of opening pressure in an unpredictable cohort of patients. This may adequately address overdrainage-related complications from early in treatment.

  14. Mass Law Predicts Hyperbolic Hypoxic Ventilatory Response

    Science.gov (United States)

    Severinghaus, John W.

    The hyperbolic hypoxic ventilatory response vs PaO2, HVRp, is interpreted as relecting a mass hyperbolic relationship of cytochrome PcO2 to cytochrome potential Ec, offset 32 torr by the constant diffusion gradient between arterial blood and cytochrome in CB at its constant metabolic rate dot VO_2 . Ec is taken to be a linear function of redox reduction and CB ventilatory drive. As Ec rises in hypoxia, the absolute potentials of each step in the citric acid cycle rises equally while the potential drop across each step remains constant because flux rate remains constant. A hypothetic HVRs ( dot VE vs SaO2) response curve computed from these assumptions is strikingly non linear. A hypothetic HVRp calculated from an assumed linear HVRs cannot be fit to the observed hyperbolic increase of ventilation in response to isocapnic hypoxia at PO2 less than 40 torr. The incompatibility of these results suggest that in future studies HVRs will not be found to be linear, especially below 80% SaO2 and HVRp will fail to be accurately hyperbolic.

  15. Psychosocial adjustment during the transition to parenthood of Portuguese couples who conceived spontaneously or through assisted reproductive technologies.

    Science.gov (United States)

    Gameiro, Sofia; Moura-Ramos, Mariana; Canavarro, Maria Cristina; Soares, Isabel

    2010-06-01

    We examined the psychosocial adjustment of 35 Portuguese couples who conceived through Assisted Reproductive Technologies (ART) and 31 couples with a spontaneous conception during their transition to parenthood (pregnancy and 4 months postpartum). Couples completed self-report questionnaires regarding their perceptions of pregnancy and parenthood, psychological distress, quality of life, marital relationship, and parenting stress. Compared with parents who conceived spontaneously, parents who conceived through ART perceived pregnancy as being more risky and demanding, reported a decrease in their psychological quality of life, and ART fathers only perceived themselves as being more competent than fathers who conceived spontaneously. Healthcare professionals should be aware of need of couples in their efforts to adapt to the individual and relational challenges associated with the transition to parenthood.

  16. A necklace sonar with adjustable scope range for assisting the visually impaired.

    Science.gov (United States)

    Villamizar, Luz H; Gualdron, Mauricio; Gonzalez, Fabio; Aceros, Juan; Rizzo-Sierra, Carlos V

    2013-01-01

    A sonar based device with tactile feedback was developed to improve the mobility and independence of visually impaired individuals. It features a transceiver/receiver, a potentiometer, a microcontroller, a rechargeable polymer lithium ion battery, and a Nokia Cell phone vibrator. All components are commercially available and housed in a custom acrylic package with 86 mm × 34 mm × 12 mm in dimension, and 120 grms in weight. Additionally, the device features an adjustable detection scheme for user customization of distance range, and a tactile feedback system that avoids interference with auditory sensory information. The device was tested for its navigational efficacy in an artificial indoor environment, and in a live outdoor setting. Ten subjects (9 males and 1 female), with a mean age of 35 years-old (range: 17 to 52) were presented with a series of navigational tasks resulting in considerable reduction of head, shoulder, chest, and arms collisions during their locomotion. We conclude that this device greatly improves the mobility and safety of visually impaired individuals.

  17. Quantifying the ventilatory control contribution to sleep apnoea using polysomnography.

    Science.gov (United States)

    Terrill, Philip I; Edwards, Bradley A; Nemati, Shamim; Butler, James P; Owens, Robert L; Eckert, Danny J; White, David P; Malhotra, Atul; Wellman, Andrew; Sands, Scott A

    2015-02-01

    Elevated loop gain, consequent to hypersensitive ventilatory control, is a primary nonanatomical cause of obstructive sleep apnoea (OSA) but it is not possible to quantify this in the clinic. Here we provide a novel method to estimate loop gain in OSA patients using routine clinical polysomnography alone. We use the concept that spontaneous ventilatory fluctuations due to apnoeas/hypopnoeas (disturbance) result in opposing changes in ventilatory drive (response) as determined by loop gain (response/disturbance). Fitting a simple ventilatory control model (including chemical and arousal contributions to ventilatory drive) to the ventilatory pattern of OSA reveals the underlying loop gain. Following mathematical-model validation, we critically tested our method in patients with OSA by comparison with a standard (continuous positive airway pressure (CPAP) drop method), and by assessing its ability to detect the known reduction in loop gain with oxygen and acetazolamide. Our method quantified loop gain from baseline polysomnography (correlation versus CPAP-estimated loop gain: n=28; r=0.63, ppolysomnography, enabling identification of likely responders to therapies targeting ventilatory control.

  18. OBESITY: CHALLENGES TO VENTILATORY CONTROL DURING EXERCISE A BRIEF REVIEW

    Science.gov (United States)

    Babb, Tony G.

    2013-01-01

    Obesity is a national health issue in the US. Among the many physiological changes induced by obesity, it also presents a unique challenge to ventilatory control during exercise due to increased metabolic demand of moving larger limbs, increased work of breathing due to extra weight on the chest wall, and changes in breathing mechanics. These challenges to ventilatory control in obesity can be inconspicuous or overt among obese adults but for the most part adaptation of ventilatory control during exercise in obesity appears remarkably unnoticed in the majority of obese people. In this brief review, the changes to ventilatory control required for maintaining normal ventilation during exercise will be examined, especially the interaction between respiratory neural drive and ventilation. Also, gaps in our current knowledge will be discussed. PMID:23707540

  19. Defining obstructive ventilatory defect in 2015

    Directory of Open Access Journals (Sweden)

    Zied Affes

    2015-10-01

    Full Text Available Introduction: There is no clear consensus as to what constitutes an obstructive ventilatory defect (OVD: Is it FEV1/FVC

  20. Brain neuropeptides in central ventilatory and cardiovascular regulation in trout.

    Directory of Open Access Journals (Sweden)

    Jean-Claude eLe Mével

    2012-10-01

    Full Text Available Many neuropeptides and their G-protein coupled receptors (GPCRs are present within the brain area involved in ventilatory and cardiovascular regulation but only a few mammalian studies have focused on the integrative physiological actions of neuropeptides on these vital cardio-respiratory regulations. Because both the central neuroanatomical substrates that govern motor ventilatory and cardiovascular output and the primary sequence of regulatory peptides and their receptors have been mostly conserved through evolution, we have developed a trout model to study the central action of native neuropeptides on cardio-ventilatory regulation. In the present review, we summarize the most recent results obtained using this non-mammalian model with a focus on PACAP, VIP, tachykinins, CRF, urotensin-1, CGRP, angiotensin-related peptides, urotensin-II, NPY, and PYY. We propose hypotheses regarding the physiological relevance of the results obtained.

  1. Effects of Breathing Resistance on Resting Ventilatory Sensitivity to CO2

    Science.gov (United States)

    2014-08-12

    BREATHING RESISTANCE ON RESTING VENTILATORY SENSITIVITY TO CO2 Authors: B. Shykoff, Ph.D...June 2013 - Feb 2014 4. TITLE AND SUBTITLE (U) EFFECTS OF BREATHING RESISTANCE ON RESTING VENTILATORY SENSITIVITY TO CO2 5a...the respiratory muscles by optimizing for their loading, ventilatory response to CO2 may be damped when resistance to breathing increases. This has

  2. Efficacy of a Ventilatory Training Mask to Improve Anaerobic and Aerobic Capacity in Reserve Officers' Training Corps Cadets.

    Science.gov (United States)

    Sellers, John H; Monaghan, Taylor P; Schnaiter, Jessica A; Jacobson, Bert H; Pope, Zachary K

    2016-04-01

    The purpose of this study was to examine the efficacy of a ventilatory training mask to improve anaerobic and aerobic fitness in reserve officers' training corps (ROTC) cadets. Seventeen ROTC cadets from a Midwest university completed pre- and postassessments consisting of anthropometry, a 30-second Wingate Anaerobic Test (WAnT), and a maximal aerobic capacity test (V[Combining Dot Above]O2max). A 6-week intervention training period was used during which time participants completed their mandatory physical training (PT) sessions. Participants were randomly assigned to either the experimental group (MASK; n = 9) or the control group (CON; n = 8). The ventilatory training masks were adjusted to simulate an altitude of 2,750 m. There was no significant effect (p ≤ 0.05) between groups on fatigue index, anaerobic capacity, peak power, V[Combining Dot Above]O2max, or time to exhaustion. These results suggest that the use of the ventilatory training mask during mandatory PT did not elicit superior aerobic or anaerobic adaptations in ROTC cadets. Therefore, it is recommended that more established simulated altitude training methods be used when incorporating intermittent hypoxic training.

  3. Ibuprofen Blunts Ventilatory Acclimatization to Sustained Hypoxia in Humans.

    Directory of Open Access Journals (Sweden)

    Kemal Erdem Basaran

    Full Text Available Ventilatory acclimatization to hypoxia is a time-dependent increase in ventilation and the hypoxic ventilatory response (HVR that involves neural plasticity in both carotid body chemoreceptors and brainstem respiratory centers. The mechanisms of such plasticity are not completely understood but recent animal studies show it can be blocked by administering ibuprofen, a nonsteroidal anti-inflammatory drug, during chronic hypoxia. We tested the hypothesis that ibuprofen would also block the increase in HVR with chronic hypoxia in humans in 15 healthy men and women using a double-blind, placebo controlled, cross-over trial. The isocapnic HVR was measured with standard methods in subjects treated with ibuprofen (400 mg every 8 hrs or placebo for 48 hours at sea level and 48 hours at high altitude (3,800 m. Subjects returned to sea level for at least 30 days prior to repeating the protocol with the opposite treatment. Ibuprofen significantly decreased the HVR after acclimatization to high altitude compared to placebo but it did not affect ventilation or arterial O2 saturation breathing ambient air at high altitude. Hence, compensatory responses prevent hypoventilation with decreased isocapnic ventilatory O2-sensitivity from ibuprofen at this altitude. The effect of ibuprofen to decrease the HVR in humans provides the first experimental evidence that a signaling mechanism described for ventilatory acclimatization to hypoxia in animal models also occurs in people. This establishes a foundation for the future experiments to test the potential role of different mechanisms for neural plasticity and ventilatory acclimatization in humans with chronic hypoxemia from lung disease.

  4. Tissue Functioning and Remodeling in the Circulatory and Ventilatory Systems

    CERN Document Server

    Thiriet, Marc

    2013-01-01

    The volumes in this authoritative series present a multidisciplinary approach to modeling and simulation of flows in the cardiovascular and ventilatory systems, especially multiscale modeling and coupled simulations. Volume 5 is devoted to cells, tissues, and organs of the cardiovascular and ventilatory systems with an emphasis on mechanotransduction-based regulation of flow. The blood vessel wall is a living tissue that quickly reacts to loads applied on it by the flowing blood. In any segment of a blood vessel, the endothelial and smooth muscle cells can sense unusual time variations in small-magnitude wall shear stress and large-amplitude wall stretch generated by abnormal hemodynamic stresses. These cells respond with a short-time scale (from seconds to hours) to adapt the vessel caliber. Since such adaptive cell activities can be described using mathematical models, a key objective of this volume is to identify the mesoscopic agents and nanoscopic mediators required to derive adequate mathematical models...

  5. Data on respiratory variables in critically ill patients with acute respiratory failure placed on proportional assist ventilation with load adjustable gain factors (PAV+).

    Science.gov (United States)

    Georgopoulos, Dimitris; Xirouchaki, Nectaria; Tzanakis, Nikolaos; Younes, Magdy

    2016-09-01

    The data show respiratory variables in 108 critically ill patients with acute respiratory failure placed on proportional assist ventilation with load adjustable gain factors (PAV+) after at least 36 h on passive mechanical ventilation. PAV+ was continued for 48 h until the patients met pre-defined criteria either for switching to controlled modes or for breathing without ventilator assistance. Data during passive mechanical ventilation and during PAV+ are reported. Data are acquired from the whole population, as well as from patients with and without acute respiratory distress syndrome. The reported variables are tidal volume, driving pressure (ΔP, the difference between static end-inspiratory plateau pressure and positive end-expiratory airway pressure), respiratory system compliance and resistance, and arterial blood gasses. The data are supplemental to our original research article, which described individual ΔP in these patients and examined how it related to ΔP when the same patients were ventilated with passive mechanical ventilation using the currently accepted lung-protective strategy "Driving pressure during assisted mechanical ventilation. Is it controlled by patient brain?" [1].

  6. Data on respiratory variables in critically ill patients with acute respiratory failure placed on proportional assist ventilation with load adjustable gain factors (PAV+

    Directory of Open Access Journals (Sweden)

    Dimitris Georgopoulos

    2016-09-01

    Full Text Available The data show respiratory variables in 108 critically ill patients with acute respiratory failure placed on proportional assist ventilation with load adjustable gain factors (PAV+ after at least 36 h on passive mechanical ventilation. PAV+ was continued for 48 h until the patients met pre-defined criteria either for switching to controlled modes or for breathing without ventilator assistance. Data during passive mechanical ventilation and during PAV+ are reported. Data are acquired from the whole population, as well as from patients with and without acute respiratory distress syndrome. The reported variables are tidal volume, driving pressure (ΔP, the difference between static end-inspiratory plateau pressure and positive end-expiratory airway pressure, respiratory system compliance and resistance, and arterial blood gasses. The data are supplemental to our original research article, which described individual ΔP in these patients and examined how it related to ΔP when the same patients were ventilated with passive mechanical ventilation using the currently accepted lung-protective strategy “Driving pressure during assisted mechanical ventilation. Is it controlled by patient brain?” [1].

  7. Ventilatory Function in Young Adults and Dietary Antioxidant Intake

    Directory of Open Access Journals (Sweden)

    Vanessa Garcia-Larsen

    2015-04-01

    Full Text Available Dietary antioxidants may protect against poor ventilatory function. We assessed the relation between ventilatory function and antioxidant components of diet in young Chileans. Forced expiratory volume in 1 s (FEV1, forced vital capacity (FVC, and the ratio FEV1/FVC were measured in 1232 adults aged 22–28 years, using a Vitalograph device. Dietary intake was ascertained with a food frequency questionnaire (FFQ designed for this study, from which nutrient and flavonoid intakes were estimated. Dietary patterns were derived with Principal Component Analysis (PCA. After controlling for potential confounders, dietary intake of total catechins was positively associated with FVC (Regression coefficient (RC of highest vs. lowest quintile of intake 0.07; 95% CI 0.01 to 0.15; p per trend 0.006. Total fruit intake was related to FVC (RC of highest vs. lowest quintile 0.08; 95% CI 0.003 to 0.15; p per trend 0.02. Intake of omega 3 fatty acids was associated with a higher FEV1 (RC for highest vs. lowest quintile 0.08; 95% CI 0.01 to 0.15 L; p per trend 0.02 and with FVC 0.08 (RC in highest vs. lowest quintile of intake 0.08, 95% CI 0.001 to 0.16; p per trend 0.04. Our results show that fresh fruits, flavonoids, and omega 3 fatty acids may contribute to maintain ventilatory function.

  8. The ventilatory effect of external oscillation.

    Science.gov (United States)

    Isabey, D; Piquet, J

    1989-01-01

    High frequency ventilation (HFV) may be achieved by external oscillation (external HFV) applied around the chest wall (HFCWO) in large animals and humans, or over the entire body (HFBSO) in small animals, instead of being applied via the trachea (internal HFV). We present a synthesis of the results obtained with external HFV in both normal and bronchoconstricted subjects. Whereas external and internal HFV were found to be equivalent in terms of gas exchange in normal rats, external HFV was found to have a beneficial effect in bronchoconstricted rabbits, but internal HFV did not. From the frequency-oscillatory tidal volume relationship determined in normocapnic rabbits, HFBSO at 5 Hz was found to be the optimal frequency at which to ventilate with tidal volumes close to the dead space volume, and which was also shown to be the optimal volume to obtain normocapnia. Moreover, 5 Hz oscillations (HFCWO) at 20 ml and 40 ml superimposed on tidal breathing accelerated nitrogen washout, i.e., gas exchange in normal humans. Unfortunately, only oscillations with much smaller volumes (5-10 ml) were obtainable in COPD patients. Nevertheless, they produced a clear change in breathing pattern associated with a slight improvement in gas exchange and a potentially positive effect on inspiratory muscle fatigue. These results support the concept that non-invasive external HFV technique may be of use in assisting ventilation in bronchoconstricted subjects and may possibly replace conventional controlled ventilation, at least in subjects with high lung compliance, such as babies, neonates and normal adults.

  9. Periodic cardiovascular and ventilatory activity during midazolam sedation.

    Science.gov (United States)

    Galletly, D C; Williams, T B; Robinson, B J

    1996-04-01

    We have examined the effects of sedation with midazolam 0.1 mg kg-1 and reversal with flumazenil 0.5 mg on beat-to-beat heart rate (HR) variability (HRV), systolic arterial pressure (SAP), finger photoplethysmograph amplitude (PLA) and impedence pneumography in eight volunteers. With the onset of sedation there was a small decrease in SAP and increase in HR (ns). Spectral analysis of the HR time series showed reductions in the proportion of power in the high (> 0.15 Hz) frequency "ventilatory" band consistent with midazolam causing vagolysis. During sedation, low frequency (midazolam sedation were reversed by administration of flumazenil.

  10. An experimental randomized study of six different ventilatory modes in a piglet model with normal lungs

    DEFF Research Database (Denmark)

    Nielsen, J B; Sjöstrand, U H; Henneberg, S W

    1991-01-01

    A randomized study of 6 ventilatory modes was made in 7 piglets with normal lungs. Using a Servo HFV 970 (prototype system) and a Servo ventilator 900 C the ventilatory modes examined were as follows: SV-20V, i.e. volume-controlled intermittent positive-pressure ventilation (IPPV); SV-20VIosc, i...

  11. Ventilatory Efficiency in Children and Adolescents: A Systematic Review

    Directory of Open Access Journals (Sweden)

    Paloma Lopes Francisco Parazzi

    2015-01-01

    Full Text Available Introduction. The index of ventilatory efficiency (VE/VCO2 obtained by the progressive exercise test has been considered the gold standard in the prognosis of adults with heart failure, but few studies have evaluated this approach in children. Objective. To verify the scientific evidence about the VE/VCO2 in pediatric and adolescents patients. Methods. A systematic literature review was carried out using the key words VE/VCO2, children, and adolescents using the PEDro and PubMed/MedLine databases. Clinical trials published from 1987 to 2014, including children, adolescents, and young adults up to 25 years, addressing the VE/VCO2 index as a method of evaluation, monitoring, and prognosis were considered. Results. Initially, 95 articles were found; 12 were excluded as the title/abstract did not contain the VE/VCO2 index or because they included patients greater than 25 years of age. From the remaining 83, 58 were repeated between the databases. The final sample consisted of 32 studies including healthy children and children with respiratory and other diseases. Conclusion. There are few studies involving cardiorespiratory assessment by ventilatory efficiency. The studies highlight the fact that high VE/VCO2 values are associated with a worse prognosis of patients due to the relationship with the decrease in pulmonary perfusion and cardiac output.

  12. Origin of the unique ventilatory apparatus of turtles.

    Science.gov (United States)

    Lyson, Tyler R; Schachner, Emma R; Botha-Brink, Jennifer; Scheyer, Torsten M; Lambertz, Markus; Bever, G S; Rubidge, Bruce S; de Queiroz, Kevin

    2014-01-01

    The turtle body plan differs markedly from that of other vertebrates and serves as a model system for studying structural and developmental evolution. Incorporation of the ribs into the turtle shell negates the costal movements that effect lung ventilation in other air-breathing amniotes. Instead, turtles have a unique abdominal-muscle-based ventilatory apparatus whose evolutionary origins have remained mysterious. Here we show through broadly comparative anatomical and histological analyses that an early member of the turtle stem lineage has several turtle-specific ventilation characters: rigid ribcage, inferred loss of intercostal muscles and osteological correlates of the primary expiratory muscle. Our results suggest that the ventilation mechanism of turtles evolved through a division of labour between the ribs and muscles of the trunk in which the abdominal muscles took on the primary ventilatory function, whereas the broadened ribs became the primary means of stabilizing the trunk. These changes occurred approximately 50 million years before the evolution of the fully ossified shell.

  13. IMPACT OF SMOKING ON ADULTS LUNG AGE AND VENTILATORY FUNCTION

    Directory of Open Access Journals (Sweden)

    Omar Farouk Helal

    2014-04-01

    Full Text Available Background: Although a large body of evidence exists on the effect of smoking on lung age and pulmonary function, much less attention has been dedicated to using these effects as an effective strategy in smoking cessation. Objective: The present study was carried out to investigate the impact of smoking on lung age and ventilatory function in adult Saudi in order to use these effects in a future strategy for smoking cessation. Methods: Eighty one smoker students with their mean age 23.88 ± 2.7 years were enrolled in this study. Every student performed a ventilatory function tests in order to measure lung age, forced vital capacity (FVC, forced expiratory volume at the end of the first second (FEV1, FEV1/FVC ratio and peak expiratory flow rate PEFR. Results: The result showed significant deterioration in the mean value of FEV1, PEFR and the estimated lung age and a non-significant difference in the mean values of FVC. Conclusion: Smoking has a significant effect on ventilaroty function and deteriorating estimated lung age.

  14. Assessment of ventilatory neuromuscular drive in patients with obstructive sleep apnea

    Directory of Open Access Journals (Sweden)

    L.R.A. Bittencourt

    1998-04-01

    Full Text Available The presence of abnormalities of the respiratory center in obstructive sleep apnea (OSA patients and their correlation with polysomnographic data are still a matter of controversy. Moderately obese, sleep-deprived OSA patients presenting daytime hypersomnolence, with normocapnia and no clinical or spirometric evidence of pulmonary disease, were selected. We assessed the ventilatory control and correlated it with polysomnographic data. Ventilatory neuromuscular drive was evaluated in these patients by measuring the ventilatory response (VE, the inspiratory occlusion pressure (P.1 and the ventilatory pattern (VT/TI, TI/TTOT at rest and during submaximal exercise, breathing room air. These analyses were also performed after inhalation of a hypercapnic mixture of CO2 (DP.1/DPETCO2, DVE/DPETCO2. Average rest and exercise ventilatory response (VE: 12.2 and 32.6 l/min, respectively, inspiratory occlusion pressure (P.1: 1.5 and 4.7 cmH2O, respectively, and ventilatory pattern (VT/TI: 0.42 and 1.09 l/s; TI/TTOT: 0.47 and 0.46 l/s, respectively were within the normal range. In response to hypercapnia, the values of ventilatory response (DVE/DPETCO2: 1.51 l min-1 mmHg-1 and inspiratory occlusion pressure (DP.1/DPETCO2: 0.22 cmH2O were normal or slightly reduced in the normocapnic OSA patients. No association or correlation between ventilatory neuromuscular drive and ventilatory pattern, hypersomnolence score and polysomnographic data was found; however a significant positive correlation was observed between P.1 and weight. Our results indicate the existence of a group of normocapnic OSA patients who have a normal awake neuromuscular ventilatory drive at rest or during exercise that is partially influenced by obesity

  15. Synthesis of cobalt-containing mesoporous catalysts using the ultrasonic-assisted "pH-adjusting" method: Importance of cobalt species in styrene oxidation

    Science.gov (United States)

    Li, Baitao; Zhu, Yanrun; Jin, Xiaojing

    2015-01-01

    Cobalt-containing SBA-15 and MCM-41 (Co-SBA-15 and Co-MCM-41) mesoporous catalysts were prepared via ultrasonic-assisted "pH-adjusting" technique in this study. Their physiochemical structures were comprehensively characterized and correlated with catalytic activity in oxidation of styrene. The nature of cobalt species depended on the type of mesoporous silica as well as pH values. The different catalytic performance between Co-SBA-15 and Co-MCM-41 catalysts originated from cobalt species. Cobalt species were homogenously incorporated into the siliceous framework of Co-SBA-15 in single-site Co(II) state, while Co3O4 particles were loaded on Co-MCM-41 catalysts. The styrene oxidation tests showed that the single-site Co(II) state was more beneficial to the catalytic oxidation of styrene. The higher styrene conversion and benzaldehyde selectivity over Co-SBA-15 catalysts were mainly attributed to single-site Co(II) state incorporated into the framework of SBA-15. The highest conversion of styrene (34.7%) with benzaldehyde selectivity of 88.2% was obtained over Co-SBA-15 catalyst prepared at pH of 7.5, at the mole ratio of 1:1 (styrene to H2O2) at 70 °C.

  16. Control of Cell Fate in the Circulatory and Ventilatory Systems

    CERN Document Server

    Thiriet, Marc

    2012-01-01

    The volumes in this authoritative series present a multidisciplinary approach to modeling and simulation of flows in the cardiovascular and ventilatory systems, especially multiscale modeling and coupled simulations. The cardiovascular and respiratory systems are tightly coupled, as their primary function is to supply oxygen to and remove carbon dioxide from the body's cells. Because physiological conduits have deformable and reactive walls, macroscopic flow behavior and prediction must be coupled to nano- and microscopic events in a corrector scheme of regulated mechanisms. Therefore, investigation of flows of blood and air in physiological conduits requires an understanding of the biology, chemistry, and physics of these systems together with the mathematical tools to describe their functioning. Volumes 1 and 2 are devoted to cell organization and fate, as well as activities that are autoregulated and/or controlled by the cell environment. Volume 1 examined cellular features that allow adaptation to env...

  17. Intracellular Signaling Mediators in the Circulatory and Ventilatory Systems

    CERN Document Server

    Thiriet, Marc

    2013-01-01

    The volumes in this authoritative series present a multidisciplinary approach to modeling and simulation of flows in the cardiovascular and ventilatory systems, especially multiscale modeling and coupled simulations. The cardiovascular and respiratory systems are tightly coupled, as their primary function is to supply oxygen to and remove carbon dioxide from the body's cells. Because physiological conduits have deformable and reactive walls, macroscopic flow behavior and prediction must be coupled to phenomenological models of nano- and microscopic events in a corrector scheme of regulated mechanisms when the vessel lumen caliber varies markedly. Therefore, investigation of flows of blood and air in physiological conduits requires an understanding of the biology, chemistry, and physics of these systems together with the mathematical tools to describe their functioning. Volume 4 is devoted to major sets of intracellular mediators that transmit signals upon stimulation of cell-surface receptors.  Activation of...

  18. Abnormalities of the Ventilatory Equivalent for Carbon Dioxide in Patients with Chronic Heart Failure

    Directory of Open Access Journals (Sweden)

    Lee Ingle

    2012-01-01

    Full Text Available Introduction. The relation between minute ventilation (VE and carbon dioxide production (VCO2 can be characterised by the instantaneous ratio of ventilation to carbon dioxide production, the ventilatory equivalent for CO2 (VEqCO2. We hypothesised that the time taken to achieve the lowest VEqCO2 (time to VEqCO2 nadir may be a prognostic marker in patients with chronic heart failure (CHF. Methods. Patients and healthy controls underwent a symptom-limited, cardiopulmonary exercise test (CPET on a treadmill to volitional exhaustion. Results. 423 patients with CHF (mean age 63±12 years; 80% males and 78 healthy controls (62% males; age 61±11 years were recruited. Time to VEqCO2 nadir was shorter in patients than controls (327±204 s versus 514±187 s; =0.0001. Univariable predictors of all-cause mortality included peak oxygen uptake (2=53.0, VEqCO2 nadir (2=47.9, and time to VEqCO2 nadir (2=24.0. In an adjusted Cox multivariable proportional hazards model, peak oxygen uptake (2=16.7 and VEqCO2 nadir (2=17.9 were the most significant independent predictors of all-cause mortality. Conclusion. The time to VEqCO2 nadir was shorter in patients with CHF than in normal subjects and was a predictor of subsequent mortality.

  19. Ventilatory pattern and associated episodic hypoxaemia in the late postoperative period in the general surgical ward

    DEFF Research Database (Denmark)

    Rosenberg, J; Rasmussen, G I; Wøjdemann, K R;

    1999-01-01

    Episodic oxygen desaturation is frequent in the late postoperative period and seems most pronounced on the second and third postoperative nights. However, the ventilatory pattern has not been described systematically during this period. We studied the ventilatory pattern and associated arterial...... oxygenation using the Edentrace II equipment (impedance pneumography and pulse oximetry) on the second and third postoperative nights in 28 patients undergoing major abdominal surgery. Ventilatory disturbances were common and included periods of hypopnoea, and obstructive, central and mixed apnoeas. Overall...... disturbances. Overall, 23% (0-100) of the hypopnoeas and 7% (0-100) of the apnoeas were associated with episodic hypoxaemia. In conclusion, ventilatory disturbances were common in the late postoperative period in the general surgical ward and often associated with episodes of oxygen desaturation....

  20. Improvement of ventilatory function by spa therapy in patients with intractable asthma.

    Directory of Open Access Journals (Sweden)

    Tanizaki,Yoshiro

    1986-02-01

    Full Text Available Twenty-five patients with intractable asthma had swimming training in a hot spring pool for 3 months. The subjects were divided into three groups according to their clinical symptoms and ages. Changes of ventilatory function during swimming training were observed in in each group. The ventilatory function test revealed that free swimming training in a hot spring pool for 30 min did not induce bronchoconstriction in any of the groups. The values of ventilatory parameters such as FEV 1.0%, %PEFR, %V50 and %V25 were improved after the 3-month swimming training. The improvement of ventilatory parameters, especially %MMF, %V50 and %V25, by the training was most remarkable in the type II asthma group. The percent increase in %MMF, %V50 and %V25 was highest in patients more than 61 years of age, and higher in patients aged 40 to 60 years than in younger patients.

  1. ADJUSTMENT FACTORS AND ADJUSTMENT STRUCTURE

    Institute of Scientific and Technical Information of China (English)

    Tao Benzao

    2003-01-01

    In this paper, adjustment factors J and R put forward by professor Zhou Jiangwen are introduced and the nature of the adjustment factors and their role in evaluating adjustment structure is discussed and proved.

  2. Evaluation of criteria for discontinuing mechanical ventilatory support.

    Science.gov (United States)

    Millbern, S M; Downs, J B; Jumper, L C; Modell, J H

    1978-12-01

    Thirty-three patients who required short-term postoperative mechanical ventilatory support were studied to compare different criteria established to initiate weaning from mechanical ventilation. Intermittent mandatory ventilation criteria (i.e., decreasing mechanical respirator rate as long as the arterial (pHa) remains above 7.35) and conventional criteria (ie, vital capacity greater than 15 ml/kg and peak negative pressure greater than 20 cm H2O) were compared to determine which would more rapidly predict a patient's ability to sustain total spontaneous respiration. All patients were eventually weaned from mechanical ventilation and had their tracheas extubated. Twenty-one patients maintained a pHa of greater than 7.35 during total spontaneous ventilation before they would, or could, meet conventional criteria for initiating a trial of spontaneous respiration (P less than .001). Seven patients simultaneously met both criteria for maintaining total spontaneous ventilation and the remaining five patients met conventional criteria before intermittent mandatory ventilation criteria. In the latter group, the pHa decreased below 7.35 during spontaneous respiration but in only one patient did it fall below 7.30. Our findings suggest that a patient's ability to maintain a pHa of greater than 7.35 while decreasing the frequency of mechanical ventilator breaths is more accurate than peak negative pressure and vital capacity for predicting ability to sustan adequate spontaneous respiration.

  3. Classic conditioning of the ventilatory responses in rats.

    Science.gov (United States)

    Nsegbe, E; Vardon, G; Perruchet, P; Gallego, J

    1997-10-01

    Recent authors have stressed the role of conditioning in the control of breathing, but experimental evidence of this role is still sparse and contradictory. To establish that classic conditioning of the ventilatory responses can occur in rats, we performed a controlled experiment in which a 1-min tone [conditioned stimulus (CS)] was paired with a hypercapnic stimulus [8.5% CO2, unconditioned stimulus (US)]. The experimental group (n = 9) received five paired CS-US presentations, followed by one CS alone to test conditioning. This sequence was repeated six times. The control group (n = 7) received the same number of CS and US, but each US was delivered 3 min after the CS. We observed that after the CS alone, breath duration was significantly longer in the experimental than in the control group and mean ventilation was significantly lower, thus showing inhibitory conditioning. This conditioning may have resulted from the association between the CS and the inhibitory and aversive effects of CO2. The present results confirmed the high sensitivity of the respiratory controller to conditioning processes.

  4. Occurrence of respiratory symptoms in persons with restrictive ventilatory impairment compared with persons with chronic obstructive pulmonary disease: The PLATINO study.

    Science.gov (United States)

    Nonato, Nívia L; Nascimento, Oliver A; Padilla, Rogelio P; de Oca, Maria M; Tálamo, Carlos; Valdivia, Gonzalo; Lisboa, Carmen; López, Maria V; Celli, Bartolomé; Menezes, Ana Maria B; Jardim, José R

    2015-08-01

    Patients with chronic obstructive pulmonary disease (COPD) usually complain of symptoms such as cough, sputum, wheezing, and dyspnea. Little is known about clinical symptoms in individuals with restrictive ventilatory impairment. The aim of this study was to compare the prevalence and type of respiratory symptoms in patients with COPD to those reported by individuals with restrictive ventilatory impairment in the Proyecto Latinoamericano de Investigacion en Obstruccion Pulmonar study. Between 2002 and 2004, individuals ≥40 years of age from five cities in Latin America performed pre and post-bronchodilator spirometry and had their respiratory symptoms recorded in a standardized questionnaire. Among the 5315 individuals evaluated, 260 (5.1%) had a restrictive spirometric diagnosis (forced vital capacity (FVC) < lower limit of normal (LLN) with forced expiratory volume in the first second to forced vital capacity ratio (FEV1/FVC) ≥ LLN; American Thoracic Society (ATS)/European Respiratory Society (ERS) 2005) and 610 (11.9%) were diagnosed with an obstructive pattern (FEV1/FVC < LLN; ATS/ERS 2005). Patients with mild restriction wheezed more ((30.8%) vs. (17.8%); p < 0.028). No difference was seen in dyspnea, cough, and sputum between the two groups after adjusting for severity stage. The health status scores for the short form 12 questionnaire were similar in restricted and obstructed patients for both physical (48.4 ± 9.4 vs. 48.3 ± 9.8) and mental (50.8 ± 10.6 vs. 50.0 ± 11.5) domains. Overall, respiratory symptoms are not frequently reported by patients with restricted and obstructed patterns as defined by spirometry. Wheezing was more frequent in patients with restricted pattern compared with those with obstructive ventilatory defect. However, the prevalence of cough, sputum production, and dyspnea are not different between the two groups when adjusted by the same severity stage.

  5. The influence of aerobic fitness status on ventilatory efficiency in patients with coronary artery disease

    Directory of Open Access Journals (Sweden)

    Danilo M.L. Prado

    2015-01-01

    Full Text Available OBJECTIVE: To test the hypotheses that 1 coronary artery disease patients with lower aerobic fitness exhibit a lower ventilatory efficiency and 2 coronary artery disease patients with lower initial aerobic fitness exhibit greater improvements in ventilatory efficiency with aerobic exercise training. METHOD: A total of 123 patients (61.0±0.7 years with coronary artery disease were divided according to aerobic fitness status into 3 groups: group 1 (n = 34, peak VO217.5 and 24.5 ml/kg/min. All patients performed a cardiorespiratory exercise test on a treadmill. Ventilatory efficiency was determined by the lowest VE/VCO2 ratio observed. The exercise training program comprised moderate-intensity aerobic exercise performed 3 times per week for 3 months. Clinicaltrials.gov: NCT02106533 RESULTS: Before intervention, group 1 exhibited both lower peak VO2 and lower ventilatory efficiency compared with the other 2 groups (p<0.05. After the exercise training program, group 1 exhibited greater improvements in aerobic fitness and ventilatory efficiency compared with the 2 other groups (group 1: ▵ = -2.5±0.5 units; group 2: ▵ = -0.8±0.3 units; and group 3: ▵ = -1.4±0.6 units, respectively; p<0.05. CONCLUSIONS: Coronary artery disease patients with lower aerobic fitness status exhibited lower ventilatory efficiency during a graded exercise test. In addition, after 3 months of aerobic exercise training, only the patients with initially lower levels of aerobic fitness exhibited greater improvements in ventilatory efficiency.

  6. Convexity Adjustments

    DEFF Research Database (Denmark)

    M. Gaspar, Raquel; Murgoci, Agatha

    2010-01-01

    A convexity adjustment (or convexity correction) in fixed income markets arises when one uses prices of standard (plain vanilla) products plus an adjustment to price nonstandard products. We explain the basic and appealing idea behind the use of convexity adjustments and focus on the situations...

  7. Diaphragm paralysis causing ventilatory failure in an adult with the rigid spine syndrome.

    Science.gov (United States)

    Efthimiou, J; McLelland, J; Round, J; Gribbin, H R; Loh, L; Spiro, S G

    1987-12-01

    A syndrome consisting of a rigid spine and myopathy predominantly affecting proximal limb muscles has been previously described in children, and as with most neuromuscular disorders, the respiratory muscles appear to be affected only at an advanced stage in the disease. We describe an adult male with this syndrome who presented with ventilatory failure caused by severe respiratory muscle weakness and who demonstrated profound nocturnal arterial oxygen desaturation, particularly during rapid eye movement sleep. Treatment with negative pressure ventilation initially resulted in only modest improvements in symptoms, blood gas tensions, and nocturnal desaturation. The cause of this only partial improvement was upper airway obstruction provoked by the mode of ventilatory support used. After tracheostomy there was a dramatic and sustained improvement in symptoms and blood gas tensions and complete abolition of nocturnal arterial oxygen desaturation. This is the first report of an adult with the rigid spine syndrome presenting with ventilatory failure and cor pulmonale due to severe respiratory muscle weakness.

  8. Noninvasive Ventilatory Correction as an Adjunct to an Experimental Systemic Reperfusion Therapy in Acute Ischemic Stroke

    Directory of Open Access Journals (Sweden)

    Kristian Barlinn

    2010-01-01

    Full Text Available Background. Obstructive sleep apnea (OSA is a common condition in patients with acute ischemic stroke and associated with early clinical deterioration and poor functional outcome. However, noninvasive ventilatory correction is hardly considered as a complementary treatment option during the treatment phase of acute ischemic stroke. Summary of Case. A 55-year-old woman with an acute middle cerebral artery (MCA occlusion received intravenous tissue plasminogen activator (tPA and enrolled into a thrombolytic research study. During tPA infusion, she became drowsy, developed apnea episodes, desaturated and neurologically deteriorated without recanalization, re-occlusion or intracerebral hemorrhage. Urgent noninvasive ventilatory correction with biphasic positive airway pressure (BiPAP reversed neurological fluctuation. Her MCA completely recanalized 24 hours later. Conclusions. Noninvasive ventilatory correction should be considered more aggressively as a complementary treatment option in selected acute stroke patients. Early initiation of BiPAP can stabilize cerebral hemodynamics and may unmask the true potential of other therapies.

  9. Periaqueductal gray matter modulates the hypercapnic ventilatory response.

    Science.gov (United States)

    Lopes, Luana T; Patrone, Luis G A; Bícego, Kênia C; Coimbra, Norberto C; Gargaglioni, Luciane H

    2012-08-01

    The periaqueductal gray (PAG) is a midbrain structure directly involved in the modulation of defensive behaviors. It has direct projections to several central nuclei that are involved in cardiorespiratory control. Although PAG stimulation is known to elicit respiratory responses, the role of the PAG in the CO(2)-drive to breathe is still unknown. The present study assessed the effect of chemical lesion of the dorsolateral and dorsomedial and ventrolateral/lateral PAG (dlPAG, dmPAG, and vPAG, respectively) on cardiorespiratory and thermal responses to hypercapnia. Ibotenic acid (IBO) or vehicle (PBS, Sham group) was injected into the dlPAG, dmPAG, or vPAG of male Wistar rats. Rats with lesions outside the dlPAG, dmPAG, or vPAG were considered as negative controls (NC). Pulmonary ventilation (VE: ), mean arterial pressure (MAP), heart rate (HR), and body temperature (Tb) were measured in unanesthetized rats during normocapnia and hypercapnic exposure (5, 15, 30 min, 7 % CO(2)). IBO lesioning of the dlPAG/dmPAG caused 31 % and 26.5 % reductions of the respiratory response to CO(2) (1,094.3 ± 115 mL/kg/min) compared with Sham (1,589.5 ± 88.1 mL/kg/min) and NC groups (1,488.2 ± 47.7 mL/kg/min), respectively. IBO lesioning of the vPAG caused 26.6 % and 21 % reductions of CO(2) hyperpnea (1,215.3 ± 108.6 mL/kg/min) compared with Sham (1,657.3 ± 173.9 mL/kg/min) and NC groups (1,537.6 ± 59.3). Basal VE: , MAP, HR, and Tb were not affected by dlPAG, dmPAG, or vPAG lesioning. The results suggest that dlPAG, dmPAG, and vPAG modulate hypercapnic ventilatory responses in rats but do not affect MAP, HR, or Tb regulation in resting conditions or during hypercapnia.

  10. Respiratory muscle training with normocapnic hyperpnea improves ventilatory pattern and thoracoabdominal coordination, and reduces oxygen desaturation during endurance exercise testing in COPD patients

    Directory of Open Access Journals (Sweden)

    Bernardi E

    2015-09-01

    Full Text Available Eva Bernardi,1 Luca Pomidori,1 Faisy Bassal,1 Marco Contoli,2 Annalisa Cogo11Biomedical Sport Studies Center, University of Ferrara, Ferrara, 2Respiratory Section, Department of Medical Sciences, University of Ferrara, Cona (FE, ItalyBackground: Few data are available about the effects of respiratory muscle training with normocapnic hyperpnea (NH in COPD. The aim is to evaluate the effects of 4 weeks of NH (Spirotiger® on ventilatory pattern, exercise capacity, and quality of life (QoL in COPD patients.Methods: Twenty-six COPD patients (three females, ages 49–82 years, were included in this study. Spirometry and maximal inspiratory pressure, St George Respiratory Questionnaire, 6-minute walk test, and symptom-limited endurance exercise test (endurance test to the limit of tolerance [tLim] at 75%–80% of peak work rate up to a Borg Score of 8–9/10 were performed before and after NH. Patients were equipped with ambulatory inductive plethysmography (LifeShirt® to evaluate ventilatory pattern and thoracoabdominal coordination (phase angle [PhA] during tLim. After four supervised sessions, subjects trained at home for 4 weeks – 10 minutes twice a day at 50% of maximal voluntary ventilation. The workload was adjusted during the training period to maintain a Borg Score of 5–6/10.Results: Twenty subjects completed the study. After NH, maximal inspiratory pressure significantly increased (81.5±31.6 vs 91.8±30.6 cmH2O, P<0.01; exercise endurance time (+150 seconds, P=0.04, 6-minute walk test (+30 meters, P=0.03, and QoL (-8, P<0.01 all increased. During tLim, the ventilatory pattern changed significantly (lower ventilation, lower respiratory rate, higher tidal volume; oxygen desaturation, PhA, and dyspnea Borg Score were lower for the same work intensity (P<0.01, P=0.02, and P<0.01, respectively; one-way ANOVA. The improvement in tidal volume and oxygen saturation after NH were significantly related (R2=0.65, P<0.01.Conclusion: As

  11. An experimental randomized study of six different ventilatory modes in a piglet model with normal lungs

    DEFF Research Database (Denmark)

    Nielsen, J B; Sjöstrand, U H; Henneberg, S W

    1991-01-01

    -controlled intermittent positive-pressure ventilation; and SV-20P denotes pressure-controlled intermittent positive-pressure ventilation. With all modes of ventilation a PEEP of 7.5 cm H2O was used. In the abbreviations used, the number denotes the ventilatory frequency in breaths per minute (bpm). HFV indicates that all...

  12. Respiratory muscle endurance is limited by lower ventilatory efficiency in post-myocardial infarction patients

    Directory of Open Access Journals (Sweden)

    Laura M. T. Neves

    2014-03-01

    Full Text Available Background: Reduced respiratory muscle endurance (RME contributes to increased dyspnea upon exertion in patients with cardiovascular disease. Objective: The objective was to characterize ventilatory and metabolic responses during RME tests in post-myocardial infarction patients without respiratory muscle weakness. Method: Twenty-nine subjects were allocated into three groups: recent myocardial infarction group (RG, n=9, less-recent myocardial infarction group (LRG, n=10, and control group (CG, n=10. They underwent two RME tests (incremental and constant pressure with ventilatory and metabolic analyses. One-way ANOVA and repeated measures one-way ANOVA, both with Tukey post-hoc, were used between groups and within subjects, respectively. Results: Patients from the RG and LRG presented lower metabolic equivalent and ventilatory efficiency than the CG on the second (50± 06, 50± 5 vs. 42± 4 and third part (50± 11, 51± 10 vs. 43± 3 of the constant pressure RME test and lower metabolic equivalent during the incremental pressure RME test. Additionally, at the peak of the incremental RME test, RG patients had lower oxygen uptake than the CG. Conclusions : Post-myocardial infarction patients present lower ventilatory efficiency during respiratory muscle endurance tests, which appears to explain their inferior performance in these tests even in the presence of lower pressure overload and lower metabolic equivalent.

  13. Do regression-based computer algorithms for determining the ventilatory threshold agree?

    Science.gov (United States)

    Ekkekakis, Panteleimon; Lind, Erik; Hall, Eric E; Petruzzello, Steven J

    2008-07-01

    The determination of the ventilatory threshold has been a persistent problem in research and clinical practice. Several computerized methods have been developed to overcome the subjectivity of visual methods but it remains unclear whether different computerized methods yield similar results. The purpose of this study was to compare nine regression-based computerized methods for the determination of the ventilatory threshold. Two samples of young and healthy volunteers (n = 30 each) participated in incremental treadmill protocols to volitional fatigue. The ventilatory data were averaged in 20-s segments and analysed with a computer program. Significant variance among methods was found in both samples (Sample 1: F = 11.50; Sample 2: F = 11.70, P < 0.001 for both). The estimates of the ventilatory threshold ranged from 2.47 litres.min(-1) (71% VO2max) to 3.13 litres.min(-1) (90% VO2max) in Sample 1 and from 2.37 litres.min(-1) (67% VO2max) to 3.03 litres.min(-1) (83% VO2max) in Sample 2. The substantial differences between methods challenge the practice of relying on any single computerized method. A standardized protocol, likely based on a combination of methods, might be necessary to increase the methodological consistency in both research and clinical practice.

  14. Physician attitudes towards ventilatory support for spinal muscular atrophy type 1 in Australasia

    NARCIS (Netherlands)

    Geevasinga, Nimeshan; Ryan, Monique M.

    2007-01-01

    Without ventilatory support, premature death from respiratory insufficiency is virtually universal in infants with spinal muscular atrophy type 1 (SMA1). With mechanical ventilation, however, long-term survival has been reported from numerous international centres. We aimed to characterize physician

  15. Chiropractic Adjustment

    Science.gov (United States)

    ... syndrome) A certain type of stroke (vertebral artery dissection) after neck manipulation Don't seek chiropractic adjustment ... Chiropractic treatment. Rochester, Minn.: Mayo Foundation for Medical Education and Research; 2015. Shekelle P, et al. Spinal ...

  16. Influence of Inspiratory Muscle Training on Ventilatory Efficiency and Cycling Performance in Normoxia and Hypoxia

    Science.gov (United States)

    Salazar-Martínez, Eduardo; Gatterer, Hannes; Burtscher, Martin; Naranjo Orellana, José; Santalla, Alfredo

    2017-01-01

    The aim of this study was to analyse the influence of inspiratory muscle training (IMT) on ventilatory efficiency, in normoxia and hypoxia, and to investigate the relationship between ventilatory efficiency and cycling performance. Sixteen sport students (23.05 ± 4.7 years; 175.11 ± 7.1 cm; 67.0 ± 19.4 kg; 46.4 ± 8.7 ml·kg−1·min−1) were randomly assigned to an inspiratory muscle training group (IMTG) and a control group (CG). The IMTG performed two training sessions/day [30 inspiratory breaths, 50% peak inspiratory pressure (Pimax), 5 days/week, 6-weeks]. Before and after the training period subjects carried out an incremental exercise test to exhaustion with gas analysis, lung function testing, and a cycling time trial test in hypoxia and normoxia. Simulated hypoxia (FiO2 = 16.45%), significantly altered the ventilatory efficiency response in all subjects (p < 0.05). Pimax increased significantly in the IMTG whereas no changes occurred in the CG (time × group, p < 0.05). Within group analyses showed that the IMTG improved ventilatory efficiency (VE/VCO2 slope; EqCO2VT2) in hypoxia (p < 0.05) and cycling time trial performance [WTTmax (W); WTTmean (W); PTF(W)] (p < 0.05) in hypoxia and normoxia. Significant correlations were not found in hypoxia nor normoxia found between ventilatory efficiency parameters (VE/VCO2 slope; LEqCO2; EqCO2VT2) and time trial performance. On the contrary the oxygen uptake efficiency slope (OUES) was highly correlated with cycling time trial performance (r = 0.89; r = 0.82; p < 0.001) under both conditions. Even though no interaction effect was found, the within group analysis may suggest that IMT reduces the negative effects of hypoxia on ventilatory efficiency. In addition, the data suggest that OUES plays an important role in submaximal cycling performance. PMID:28337149

  17. 24 CFR 886.312 - Rent adjustments.

    Science.gov (United States)

    2010-04-01

    ... levels of such expenses in comparable assisted and unassisted housing in the area to ensure that... assisted and comparable unassisted units. Contract rents may be adjusted upward or downward as may be...) Comparability between assisted and unassisted units. Notwithstanding any other provisions of this...

  18. Employment Assistance: Strategic Adjustment of Rural Poverty Reduction Should Be Orientation%就业援助是农村扶贫战略调整的应有取向

    Institute of Scientific and Technical Information of China (English)

    周毕芬

    2012-01-01

    本文分析了我国农村扶贫战略先后经历的从救济式扶贫、区域开发式扶贫,向整村推进扶贫、最低生活保障制度扶贫的转变的局限性,认为当前农村扶贫战略应朝就业援助方向调整,并提出从“上游”、“中游”、“下游”三个维度实施就业援助政策措施.%China's rural poverty alleviation strategy has undergone the relief-type approach, regional development-oriented aid, the whole village to promote poverty alleviation, and minimum life guarantee system change of poverty alleviation. This paper analyzed the limitation of the traditional above poverty eradication strategies, thinks that the current rural poverty alleviation strategy toward employment assistance direction should be adjusted, and put forward from "upstream", "middle" and "downstream" three dimensions implementation employment assistance policy measures.

  19. Salary adjustments

    CERN Multimedia

    HR Department

    2008-01-01

    In accordance with decisions taken by the Finance Committee and Council in December 2007, salaries are adjusted with effect from 1 January 2008. Scale of basic salaries and scale of stipends paid to fellows (Annex R A 5 and R A 6 respectively): increased by 0.71% with effect from 1 January 2008. As a result of the stability of the Geneva consumer price index, the following elements do not increase: a)\tFamily Allowance, Child Allowance and Infant Allowance (Annex R A 3); b)\tReimbursement of education fees: maximum amounts of reimbursement (Annex R A 4.01) for the academic year 2007/2008. Related adjustments will be applied, wherever applicable, to Paid Associates and Students. As in the past, the actual percentage increase of each salary position may vary, due to the application of a constant step value and rounding effects. Human Resources Department Tel. 73566

  20. Salary adjustments

    CERN Multimedia

    HR Department

    2008-01-01

    In accordance with decisions taken by the Finance Committee and Council in December 2007, salaries are adjusted with effect from 1 January 2008. Scale of basic salaries and scale of stipends paid to fellows (Annex R A 5 and R A 6 respectively): increased by 0.71% with effect from 1 January 2008. As a result of the stability of the Geneva consumer price index, following elements do not increase: a) Family Allowance, Child Allowance and Infant Allowance (Annex R A 3). b) Reimbursement of education fees: maximum amounts of reimbursement (Annex R A 4.01) for the academic year 2007/2008. Related adjustments will be implemented, wherever applicable, to Paid Associates and Students. As in the past, the actual percentage increase of each salary position may vary, due to the application of a constant step value and the rounding effects. Human Resources Department Tel. 73566

  1. Cardiac Resynchronization Therapy Reduces Metaboreflex Contribution to the Ventilatory Response in Heart Failure Population

    Directory of Open Access Journals (Sweden)

    Jérémie Jaussaud

    2012-01-01

    Full Text Available Background. Metaboreflex overactivation has been proprosed to explain exaggerated hyperventilation in heart failure population. We investigated the metaboreflex activation after cardiac resynchronization therapy (CRT. Methods. 10 heart failure patients (mean left ventricular ejection fraction (LVEF 27±4% schedulded for CRT implantation were prospectively studied. At baseline and after 6 month follow up two maximal cardiopulmonary exercise tests with and without regional circulatory occlusion (RCO during recovery were performed. RCO was achieved by inflation of bilateral upper thigh tourniquets 30 mmHg above peak systolic blood pressure during 3 minutes after peak exercise. Metaboreflex contribution to the ventilatory response was assessed as the difference in ventilatory data at the third minute during recovery between the two tests (Δ. Results. Patients had enhanced VE/VCO2 slope (40±9 and an evident metaboreflex contribution to the high ventilatory response (ΔVE: 3±4 L/min; =0.05, ΔRR: 4.5±4/min; =0.003 and ΔVE/VCO2: 5.5±4; =0.007. 6 months after CRT implantation, NYHA class, LVEF, peak VO2 and VE/VCO2 were significantly improved (1.4±0.5; <0.001, 42±7%; <0.001, 16.5±3 mL/kg/min; =0.003; 33±10; =0.01. Metaboreflex contribution to VE, RR, and VE/VCO2 was reduced compared with baseline (=0.08, =0.01 and =0.4 resp.. Conclusion. 6 months after CRT metaboreflex contribution to the ventilatory response is reduced.

  2. Influence of gender on ventilatory efficiency during exercise in young children.

    Science.gov (United States)

    Guerrero, Laura; Naranjo, José; Carranza, M Dolores

    2008-11-01

    In this study, we assessed the ventilatory response in 84 children (46 males: age 8.1 +/- 1.0 years, body mass 34.2 +/- 7.9 kg, height 1.32 +/- 0.16 m; 38 females: age 8.0 +/- 0.8 years, body mass 31.7 +/- 8.7 kg, height 1.31 +/- 0.08 m) during a cycle ergometer test to determine if there was an influence of gender on ventilatory efficiency. The test commenced at 25 W and increased by 10 W every minute. Expired air was collected through a face mask and analysed breath by breath. The ventilatory anaerobic threshold was determined according to gas exchange methods and we focused our attention on the analysis of carbon dioxide production (VCO(2)), ventilation (V(E)), the ratio V(E)/VCO(2) and its slope. Differences between the sexes at maximal power output were strongly significant for V(E) and VCO(2) (P = 0.0001 and P = 0.0004 respectively) and moderately significant for the V(E)/VCO(2) ratio (P = 0.05). The slope of V(E) versus VCO(2) was 30.8 +/- 4.2 for males and 29.4 +/- 3.2 for females, with no difference between the sexes (P = 0.1). In conclusion, although the peak values of V(E) and VCO(2) were significantly different between the sexes, there were no such differences in ventilatory efficiency during a maximal incremental test expressed as the slope of V(E)/VCO(2), at least in young children.

  3. Withdrawal of ventilatory support outside the intensive care unit: guidance for practice

    OpenAIRE

    Laddie, Joanna; Craig, Finella; Brierley, Joe; Kelly, Paula; Bluebond-Langner, Myra

    2014-01-01

    Objective To review the work of one tertiary paediatric palliative care service in facilitating planned withdrawal of ventilatory support outside the intensive care setting, with the purpose of developing local guidance for practice. Methods Retrospective 10-year (2003–2012) case note review of intensive care patients whose parents elected to withdraw ventilation in another setting. Demographic and clinical data revealed common themes and specific incidents relevant to local guideline develop...

  4. Management of Ventilatory Insufficiency in Neuromuscular Patients Using Mechanical Ventilator Supported by the Korean Government.

    Science.gov (United States)

    Kang, Seong-Woong; Choi, Won Ah; Cho, Han Eol; Lee, Jang Woo; Park, Jung Hyun

    2016-06-01

    Since 2001, financial support has been provided for all patients with neuromuscular disease (NMD) who require ventilatory support due to the paralysis of respiratory muscles in Korea. The purpose of this study was to identify ventilator usage status and appropriateness in these patients. We included 992 subjects with rare and incurable NMD registered for ventilator rental fee support. From 21 February 2011 to 17 January 2013, ventilator usage information, regular follow-up observation, and symptoms of chronic hypoventilation were surveyed by phone. Home visits were conducted for patients judged by an expert medical team to require medical examination. Abnormal ventilatory status was assessed by respiratory evaluation. Chronic respiratory insufficiency symptoms were reported by 169 of 992 subjects (17%), while 565 subjects (57%) did not receive regular respiratory evaluation. Ventilatory status was abnormal in 102 of 343 home-visit subjects (29.7%). Although 556 subjects (56%) reported 24-hour ventilator use, only 458 (46%) had an oxygen saturation monitoring device, and 305 (31%) performed an airstacking exercise. A management system that integrates ventilator usage monitoring, counselling and advice, and home visits for patients who receive ventilator support could improve the efficiency of the ventilator support project.

  5. Body temperature depression and peripheral heat loss accompany the metabolic and ventilatory responses to hypoxia in low and high altitude birds.

    Science.gov (United States)

    Scott, Graham R; Cadena, Viviana; Tattersall, Glenn J; Milsom, William K

    2008-04-01

    The objectives of this study were to compare the thermoregulatory, metabolic and ventilatory responses to hypoxia of the high altitude bar-headed goose with low altitude waterfowl. All birds were found to reduce body temperature (T(b)) during hypoxia, by up to 1-1.5 degrees C in severe hypoxia. During prolonged hypoxia, T(b) stabilized at a new lower temperature. A regulated increase in heat loss contributed to T(b) depression as reflected by increases in bill surface temperatures (up to 5 degrees C) during hypoxia. Bill warming required peripheral chemoreceptor inputs, since vagotomy abolished this response to hypoxia. T(b) depression could still occur without bill warming, however, because vagotomized birds reduced T(b) as much as intact birds. Compared to both greylag geese and pekin ducks, bar-headed geese required more severe hypoxia to initiate T(b) depression and heat loss from the bill. However, when T(b) depression or bill warming were expressed relative to arterial O(2) concentration (rather than inspired O(2)) all species were similar; this suggests that enhanced O(2) loading, rather than differences in thermoregulatory control centres, reduces T(b) depression during hypoxia in bar-headed geese. Correspondingly, bar-headed geese maintained higher rates of metabolism during severe hypoxia (7% inspired O(2)), but this was only partly due to differences in T(b). Time domains of the hypoxic ventilatory response also appeared to differ between bar-headed geese and low altitude species. Overall, our results suggest that birds can adjust peripheral heat dissipation to facilitate T(b) depression during hypoxia, and that bar-headed geese minimize T(b) and metabolic depression as a result of evolutionary adaptations that enhance O(2) transport.

  6. The effects of acute L-carnitine administration on ventilatory breakpoint and exercise performanceduring incremental exercise

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    Mojtaba Kaviani

    2009-01-01

    Full Text Available (Received 31 October, 2009 ; Accepted 10 March, 2010AbstractBackground and purpose: Many athletes adopt nutritional manipulations to improve their performance. Among the substances generally consumed is carnitine (L-trimethyl-3-hydroxy-ammoniobutanoate which has been used by athletes as an ergogenic aid, due to its role in the transport of long-chain fatty acids across mitochondrial membranes. Nutritional supplements containing carbohydrates, proteins, vitamins, and minerals have been widely used in various sporting fields to provide a boost to the recommended daily allowance. The aim of this study is to investigate the effects of acute L-carnitine administration on ventilatory breakpoint, an exercise performance during incremental exercise.Materials and methods: This study was double-blind, randomized and crossover in design. The subjects were 12 randomly selected active male physical education students, 21.75±0.64 years old, with a mean body mass index (BMI of 23.7±0.94kg/m2, divided into 2 groups. They received orally either 2g of L-carnitine dissolved in 200 ml of water, plus 6 drops of lemon juice or a placebo (6 ml lemon juice dissolved in 200 ml of water 90 minutes before they began to exercise on a treadmill. They performed a modified protocol of Conconi test to exhaustion. One-way analysis of variance with repeated measurements was used for data analysis.Results: The results showed that exercise performance improved in LC group (2980±155 meter compared with placebo group (2331±51 meter. Furthermore, no significant difference was found in ventilatory breakpoint between the two groups.Conclusion: This finding indicates that administration of L- Carnitine, 90 minutes prior to exercise may improve performance; despite the ventilatory breakpoint as one of the anaerobic system indices that had no effect. J Mazand Univ Med Sci 2009; 19(73: 43-50 (Persian.

  7. Anaerobic threshold assessment through the ventilatory method during roller-ski skating testing: right or wrong?

    Science.gov (United States)

    Fabre, Nicolas; Bortolan, Lorenzo; Pellegrini, Barbara; Zerbini, Livio; Mourot, Laurent; Schena, Federico

    2012-02-01

    This study aimed at questioning the validity of the ventilatory method to determine the anaerobic threshold (respiratory compensation point [RCP]) during an incremental roller-ski skating test to exhaustion. Nine elite crosscountry skiers were evaluated. The skiers carried out an incremental roller-ski test on a treadmill with the V2 skating technique. Ventilatory parameters were continuously collected breath by breath, thanks to a portable gas exchange measurement system. Poling signal was obtained using instrumented ski poles. For each stage, ventilatory and poling signals were synchronized and averaged. The poor coefficient of interobserver reliability for the time at RCP confirmed the great difficulty felt by the 3 blinded reviewers for the RCP determination. Moreover, the reviewer agreed with the impossibility of determining RCP in 4 of the 9 skiers. There was no significant difference between breathing frequency (Bf) and poling frequency (Pf) during the last 8 stages. However, it seems that the differences observed during the first stages arose from the use of either a strictly 1:1 or a 1:2 Bf to Pf ratio when the exercise intensity was still moderate. So, even if there were significant differences between the frequencies, the Bf was strictly subordinate to the Pf during the entire test. In the same way, the normalized tidal volume and peak poling forces curves were superposable. These findings showed that when the upper body is mainly involved in the propulsion, the determinants of the ventilation are strictly dependent on the poling pattern during an incremental test to exhaustion. Thus, during roller-ski skating, the determination of RCP must be used cautiously because too much depending on mechanical factors.

  8. Effects of aging and training status on ventilatory response during incremental cycling exercise.

    Science.gov (United States)

    Lenti, Mauro; De Vito, Giuseppe; Scotto di Palumbo, Alessandro; Sbriccoli, Paola; Quattrini, Filippo M; Sacchetti, Massimo

    2011-05-01

    The aim of this study was to examine the effect of aging and training status on ventilatory response during incremental cycling exercise. Eight young (24 ± 5 years) and 8 older (64 ± 3 years) competitive cyclists together with 8 young (27 ± 4 years) and 8 older (63 ± 2 years) untrained individuals underwent a continuous incremental cycling test to exhaustion to determine ventilatory threshold (VT), respiratory compensation point (RCP), and maximal oxygen uptake (VO₂max). In addition, the isocapnic buffering (IB) phase was calculated together with the hypocapnic hyperventilation. Ventilatory threshold occurred at similar relative exercise intensities in all groups, whereas RCP was recorded at higher intensities in young and older cyclists compared to the untrained subjects. The IB phase, reported as the difference between VT and RCP and expressed either in absolute (ml·min⁻¹·kg⁻¹ VO₂) or in relative terms, was greater (p < 0.01) in both young and older trained cyclists than in untrained subjects, who were also characterized by a lower exercise capacity. Isocapnic buffering was particularly small in the older untrained volunteers. Although young untrained and older trained subjects had a similar level of VO₂max, older athletes exhibited a larger IB. In addition, a higher absolute but similar relative IB was observed in young vs. older cyclists, despite a higher VO₂max in the former. In conclusion, the present study shows that aging is associated with a reduction of the IB phase recorded during an incremental exercise test. Moreover, endurance training induces adaptations that result in an enlargement of the IB phase independent of age. This information can be used for the characterization and monitoring of the physiological adaptations induced by endurance training.

  9. Validity and Reliability of Ventilatory and Blood Lactate Thresholds in Well-Trained Cyclists

    Science.gov (United States)

    Pallarés, Jesús G.; Morán-Navarro, Ricardo; Ortega, Juan Fernando; Fernández-Elías, Valentín Emilio; Mora-Rodriguez, Ricardo

    2016-01-01

    Purpose The purpose of this study was to determine, i) the reliability of blood lactate and ventilatory-based thresholds, ii) the lactate threshold that corresponds with each ventilatory threshold (VT1 and VT2) and with maximal lactate steady state test (MLSS) as a proxy of cycling performance. Methods Fourteen aerobically-trained male cyclists (V˙O2max 62.1±4.6 ml·kg-1·min-1) performed two graded exercise tests (50 W warm-up followed by 25 W·min-1) to exhaustion. Blood lactate, V˙O2 and V˙CO2 data were collected at every stage. Workloads at VT1 (rise in V˙E/V˙O2;) and VT2 (rise in V˙E/V˙CO2) were compared with workloads at lactate thresholds. Several continuous tests were needed to detect the MLSS workload. Agreement and differences among tests were assessed with ANOVA, ICC and Bland-Altman. Reliability of each test was evaluated using ICC, CV and Bland-Altman plots. Results Workloads at lactate threshold (LT) and LT+2.0 mMol·L-1 matched the ones for VT1 and VT2, respectively (p = 0.147 and 0.539; r = 0.72 and 0.80; Bias = -13.6 and 2.8, respectively). Furthermore, workload at LT+0.5 mMol·L-1 coincided with MLSS workload (p = 0.449; r = 0.78; Bias = -4.5). Lactate threshold tests had high reliability (CV = 3.4–3.7%; r = 0.85–0.89; Bias = -2.1–3.0) except for DMAX method (CV = 10.3%; r = 0.57; Bias = 15.4). Ventilatory thresholds show high reliability (CV = 1.6%–3.5%; r = 0.90–0.96; Bias = -1.8–2.9) except for RER = 1 and V-Slope (CV = 5.0–6.4%; r = 0.79; Bias = -5.6–12.4). Conclusions Lactate threshold tests can be a valid and reliable alternative to ventilatory thresholds to identify the workloads at the transition from aerobic to anaerobic metabolism. PMID:27657502

  10. Unusual features in chronic inflammatory demyelinating polyneuropathy: Good outcome after prolonged ventilatory support

    Directory of Open Access Journals (Sweden)

    Sanjeev Jha

    2011-01-01

    Full Text Available Severe respiratory muscle paralysis and ventilatory failure is rare in chronic inflammatory demyelinating polyneuropathy (CIDP. We report a 14 year child who presented with respiratory failure, bulbar and multiple cranial nerves involvement along with bilateral phrenic nerve paralysis. He was diagnosed with CIDP after electrophysiological evaluation. He required AMBU ventilation for about 4 months (including domiciliary use, after which he recovered significantly. Along with several unusual features of CIDP, this report highlights good example of steady basic intensive care to save lives and rewarding outcome of prolonged respiratory support, provided by AMBU ventilation which is a rather primitive, but inexpensive device.

  11. 24 CFR 891.645 - Adjustment of utility allowances.

    Science.gov (United States)

    2010-04-01

    ... 24 Housing and Urban Development 4 2010-04-01 2010-04-01 false Adjustment of utility allowances... Handicapped-Section 8 Assistance § 891.645 Adjustment of utility allowances. In connection with adjustments of contract rents as provided in § 891.640(a), the requirements for the adjustment of utility...

  12. 24 CFR 886.112 - Rent adjustments.

    Science.gov (United States)

    2010-04-01

    ... Adjustment Factor most recently published by HUD in the Federal Register in accordance with 24 CFR part 888... unassisted housing in the area to ensure that adjustments in the Contract Rents shall not result in material differences between the rents charged for assisted and comparable unassisted units. Contract Rents may...

  13. The midpoint between ventilatory thresholds approaches maximal lactate steady state intensity in amateur cyclists

    Science.gov (United States)

    Filho, DM Pessôa; Díaz, V; Benito, PJ; Álvarez-Sánchez, M; Zapico, AG; Calderón, FJ

    2016-01-01

    The aim was to determine whether the midpoint between ventilatory thresholds (MPVT) corresponds to maximal lactate steady state (MLSS). Twelve amateur cyclists (21.0 ± 2.6 years old; 72.2 ± 9.0 kg; 179.8 ± 7.5 cm) performed an incremental test (25 W·min-1) until exhaustion and several constant load tests of 30 minutes to determine MLSS, on different occasions. Using MLSS determination as the reference method, the agreement with five other parameters (MPVT; first and second ventilatory thresholds: VT1 and VT2; respiratory exchange ratio equal to 1: RER = 1.00; and Maximum) was analysed by the Bland-Altman method. The difference between workload at MLSS and VT1, VT2, RER=1.00 and Maximum was 31.1 ± 20.0, -86.0 ± 18.3, -63.6 ± 26.3 and -192.3 ± 48.6 W, respectively. MLSS was underestimated from VT1 and overestimated from VT2, RER = 1.00 and Maximum. The smallest difference (-27.5 ± 15.1 W) between workload at MLSS and MPVT was in better agreement than other analysed parameters of intensity in cycling. The main finding is that MPVT approached the workload at MLSS in amateur cyclists, and can be used to estimate maximal steady state. PMID:28090142

  14. Excess ventilation and ventilatory constraints during exercise in patients with chronic obstructive pulmonary disease.

    Science.gov (United States)

    Teopompi, Elisabetta; Tzani, Panagiota; Aiello, Marina; Gioia, Maria Rosaria; Marangio, Emilio; Chetta, Alfredo

    2014-06-15

    We assessed the relationship between minute ventilation/carbon dioxide output (VE/VCO2) and ventilatory constraints during an incremental cardiopulmonary exercise testing (CPET) in patients with chronic obstructive pulmonary disease (COPD). Slope and intercept of the VE/VCO2 linear relationship, the ratios of inspiratory capacity/total lung capacity (IC/TLC) and of tidal volume (VT) over vital capacity (VTpeak/VC) and IC (VTpeak/IC) and over forced expiratory volume at 1st second (VTpeak/FEV1) at peak of exercise were measured in 52 COPD patients during a CPET. The difference peak-rest in end-tidal pressure of CO2 (PETCO2) was also measured. VE/VCO2 intercept showed a negative correlation with IC/TLC peak (pCOPD, VE/VCO2 slope and intercept provide complementary information on the ventilatory limitation to exercise, as assessed by changes in the end-expiratory lung volume and in tidal volume excursion.

  15. CESAR: conventional ventilatory support vs extracorporeal membrane oxygenation for severe adult respiratory failure

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    Mugford Miranda

    2006-12-01

    Full Text Available Abstract Background An estimated 350 adults develop severe, but potentially reversible respiratory failure in the UK annually. Current management uses intermittent positive pressure ventilation, but barotrauma, volutrauma and oxygen toxicity can prevent lung recovery. An alternative treatment, extracorporeal membrane oxygenation, uses cardio-pulmonary bypass technology to temporarily provide gas exchange, allowing ventilator settings to be reduced. While extracorporeal membrane oxygenation is proven to result in improved outcome when compared to conventional ventilation in neonates with severe respiratory failure, there is currently no good evidence from randomised controlled trials to compare these managements for important clinical outcomes in adults, although evidence from case series is promising. Methods/Design The aim of the randomised controlled trial of Conventional ventilatory support vs extracorporeal membrane oxygenation for severe adult respiratory failure (CESAR is to assess whether, for patients with severe, but potentially reversible, respiratory failure, extracorporeal membrane oxygenation will increase the rate of survival without severe disability ('confined to bed' and 'unable to wash or dress' by six months post-randomisation, and be cost effective from the viewpoints of the NHS and society, compared to conventional ventilatory support. Following assent from a relative, adults (18–65 years with severe, but potentially reversible, respiratory failure (Murray score ≥ 3.0 or hypercapnea with pH Discussion Analysis will be based on intention to treat. A concurrent economic evaluation will also be performed to compare the costs and outcomes of both treatments.

  16. Behavioral, Ventilatory and Thermoregulatory Responses to Hypercapnia and Hypoxia in the Wistar Audiogenic Rat (WAR Strain.

    Directory of Open Access Journals (Sweden)

    Érica Maria Granjeiro

    Full Text Available We investigated the behavioral, respiratory, and thermoregulatory responses elicited by acute exposure to both hypercapnic and hypoxic environments in Wistar audiogenic rats (WARs. The WAR strain represents a genetic animal model of epilepsy.Behavioral analyses were performed using neuroethological methods, and flowcharts were constructed to illustrate behavioral findings. The body plethysmography method was used to obtain pulmonary ventilation (VE measurements, and body temperature (Tb measurements were taken via temperature sensors implanted in the abdominal cavities of the animals.No significant difference was observed between the WAR and Wistar control group with respect to the thermoregulatory response elicited by exposure to both acute hypercapnia and acute hypoxia (p>0.05. However, we found that the VE of WARs was attenuated relative to that of Wistar control animals during exposure to both hypercapnic (WAR: 133 ± 11% vs. Wistar: 243 ± 23%, p<0.01 and hypoxic conditions (WAR: 138 ± 8% vs. Wistar: 177 ± 8%; p<0.01. In addition, we noted that this ventilatory attenuation was followed by alterations in the behavioral responses of these animals.Our results indicate that WARs, a genetic model of epilepsy, have important alterations in their ability to compensate for changes in levels of various arterial blood gasses. WARs present an attenuated ventilatory response to an increased PaCO2 or decreased PaO2, coupled to behavioral changes, which make them a suitable model to further study respiratory risks associated to epilepsy.

  17. Heart rate deflection point relates to second ventilatory threshold in a tennis test.

    Science.gov (United States)

    Baiget, Ernest; Fernández-Fernández, Jaime; Iglesias, Xavier; Rodríguez, Ferran A

    2015-03-01

    The relationship between heart rate deflection point (HRDP) and the second ventilatory threshold (VT2) has been studied in continuous sports, but never in a tennis-specific test. The aim of the study was to assess the relationships between HRDP and the VT2, and between the maximal test performance and the maximal oxygen uptake ((Equation is included in full-text article.)) in an on-court specific endurance tennis test. Thirty-five high-level tennis players performed a progressive tennis-specific field test to exhaustion to determine HRDP, VT2, and (Equation is included in full-text article.). Ventilatory gas exchange parameters were continuously recorded by a portable telemetric breath-by-breath gas exchange measurement system. Heart rate deflection point was identified at the point at which the slope values of the linear portion of the time/heart rate (HR) relationship began to decline and was successfully determined in 91.4% of the players. High correlations (r = 0.79-0.96; p tennis test can be used to determine the VT2, and the BallfHRDP can be used as a practical performance variable to prescribe on-court specific aerobic training at or near VT2.

  18. Impaired ventilatory and thermoregulatory responses to hypoxic stress in newborn Phox2b heterozygous knockout mice

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    Nelina eRamanantsoa

    2011-09-01

    Full Text Available The Phox2b gene is necessary for the development of the autonomic nervous system, and especially, of respiratory neuronal circuits. In the present study, we examined the role of Phox2b in ventilatory and thermoregulatory responses to hypoxic stress, which are closely related in the postnatal period. Hypoxic stress was generated by strong thermal stimulus, combined or not with reduced inspired O2. To this end, we exposed 6-day-old Phox2b+/- pups and their wild-type littermates (Phox2b+/+ to hypoxia (10% O2 or hypercapnia (8% CO2 under thermoneutral (33°C or cold (26°C conditions. We found that Phox2b+/- pups showed less normoxic ventilation (VE in the cold than Phox2b+/+ pups. Phox2b+/- pups also showed lower oxygen consumption (VO2 in the cold, reflecting reduced thermogenesis and a lower body temperature. Furthermore, while the cold depressed ventilatory responses to hypoxia and hypercapnia in both genotype groups, this effect was less pronounced in Phox2b+/- pups. Finally, because serotonin (5-HT neurons are pivotal to respiratory and thermoregulatory circuits and depend on Phox2b for their differentiation, we studied 5-HT metabolism using high-pressure liquid chromatography, and found that it was altered in Phox2b+/- pups. We conclude that Phox2b haploinsufficiency alters the ability of newborns to cope with metabolic challenges, possibly due to 5-HT signaling impairments.

  19. Inductive plethysmography potential as a surrogate for ventilatory measurements during rest and moderate physical exercise

    Science.gov (United States)

    Cabiddu, Ramona; Pantoni, Camila B. F.; Mendes, Renata G.; Trimer, Renata; Catai, Aparecida M.; Borghi-Silva, Audrey

    2016-01-01

    Background: Portable respiratory inductive plethysmography (RIP) systems have been validated for ventilatory assessment during resting conditions and during incremental treadmill exercise. However, in clinical settings and during field-based exercise, intensity is usually constant and submaximal. A demonstration of the ability of RIP to detect respiratory measurements accurately during constant intensity conditions would promote and validate the routine use of portable RIP devices as an alternative to ergospirometry (ES), the current gold standard technique for ventilatory measures. Objective: To investigate the agreement between respiratory variables recorded by a portable RIP device and by ES during rest and constant intensity exercise. Method: Tidal volume (VT), respiratory rate (RR) and minute ventilation (VE) were concurrently acquired by portable RIP and ES in seven healthy male volunteers during standing rest position and constant intensity treadmill exercise. Results: Significant agreement was found between RIP and ES acquisitions during the standing rest position and constant intensity treadmill exercise for RR and during the standing rest position for VE. Conclusion: Our results suggest that portable RIP devices might represent a suitable alternative to ES during rest and during constant submaximal exercise. PMID:26982454

  20. Reduced suppression of CO2-induced ventilatory stimulation by endomorphins relative to morphine.

    Science.gov (United States)

    Czapla, Marc A; Zadina, James E

    2005-10-19

    Opioids are among the most effective analgesics, but a major limitation for their therapeutic usefulness is their induction of respiratory depression. Endomorphin-1 (EM1), in contrast to several other mu opioids, exhibits a threshold for respiratory depression that is well above its threshold for analgesia. Its effect on sensitivity to CO(2), however, remains unknown. Minute ventilation (V(E)) in 2, 4, and 6% CO(2) was measured before and after systemic administration of EM1, endomorphin-2 (EM2), DAMGO, and morphine in the conscious rat. EM1 and EM2 attenuated the hypercapnic ventilatory response (HCVR) only in high doses, while DAMGO and morphine diminished the HCVR in much lower doses. The ventilatory effects of high doses of all 4 agonists were blocked by the mu-opioid antagonist naloxone (0.4 mg/kg i.v.), but not by the peripherally restricted mu-opioid antagonist, methyl-naloxone (0.4 mg/kg i.v.). It was concluded that the endomorphins attenuated the HCVR only in large doses, well beyond the analgesic threshold, and did so through a centrally mediated mu-opioid mechanism.

  1. The acute hypoxic ventilatory response under halothane, isoflurane, and sevoflurane anaesthesia in rats.

    Science.gov (United States)

    Karanovic, N; Pecotic, R; Valic, M; Jeroncic, A; Carev, M; Karanovic, S; Ujevic, A; Dogas, Z

    2010-03-01

    The relative order of potency of anaesthetic agents on the hypoxic ventilatory response has been tested in humans, but animal data are sparse. We examined the effects of 1.4, 1.6, 1.8, and 2.0 MAC halothane, isoflurane, and sevoflurane on phrenic nerve activity in euoxia (baseline) and during acute normocapnic hypoxia (inspired oxygen fraction 0.09) in adult male Sprague-Dawley rats. With halothane, all animals became apnoeic even in euoxia, and the hypoxic response was completely abolished at all anaesthetic levels. With isoflurane, 5 of 14 animals exhibited phrenic nerve activity in euoxia at 1.4 MAC and demonstrated a hypoxic response (302% of baseline activity), but all became apnoeic and lost the hypoxic response at higher doses. With sevoflurane, phrenic nerve activity and a hypoxic response was preserved in at least some animals at all doses (i.e. even the highest dose of 2.0 MAC). Similar to the rank order of potency previously observed in humans, the relative order of potency of depression of the hypoxic ventilatory response in rats was halothane (most depressive) > isoflurane > sevoflurane (p = 0.01 for differences between agents).

  2. Disorders of Sleep and Ventilatory Control in Prader-Willi Syndrome

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    Emily S. Gillett

    2016-07-01

    Full Text Available Prader-Willi syndrome (PWS is an imprinted genetic disorder conferred by loss of paternal gene expression from chromosome 15q11.2-q13. Individuals with PWS have impairments in ventilatory control and are predisposed toward sleep disordered breathing due to a combination of characteristic craniofacial features, obesity, hypotonia, and hypothalamic dysfunction. Children with PWS progress from failure to thrive during infancy to hyperphagia and morbid obesity during later childhood and onward. Similarly, the phenotype of sleep disordered breathing in PWS patients also evolves over time from predominantly central sleep apnea in infants to obstructive sleep apnea (OSA in older children. Behavioral difficulties are common and may make establishing effective therapy with continuous positive airway pressure (CPAP more challenging when OSA persists after adenotonsillectomy. Excessive daytime sleepiness (EDS is also common in patients with PWS and may continue after OSA is effectively treated. We describe here the characteristic ventilatory control deficits, sleep disordered breathing, and excessive daytime sleepiness seen in individuals with PWS. We review respiratory issues that may contribute to sudden death events in PWS patients during sleep and wakefulness. We also discuss therapeutic options for treating sleep disordered breathing including adenotonsillectomy, weight loss, and CPAP. Lastly, we discuss the benefits and safety considerations related to growth hormone therapy.

  3. The von Hippel-Lindau Chuvash mutation in mice causes carotid-body hyperplasia and enhanced ventilatory sensitivity to hypoxia.

    Science.gov (United States)

    Slingo, Mary E; Turner, Philip J; Christian, Helen C; Buckler, Keith J; Robbins, Peter A

    2014-04-01

    The hypoxia-inducible factor (HIF) family of transcription factors coordinates diverse cellular and systemic responses to hypoxia. Chuvash polycythemia (CP) is an autosomal recessive disorder in humans in which there is impaired oxygen-dependent degradation of HIF, resulting in long-term systemic elevation of HIF levels at normal oxygen tensions. CP patients demonstrate the characteristic features of ventilatory acclimatization to hypoxia, namely, an elevated baseline ventilation and enhanced acute hypoxic ventilatory response (AHVR). We investigated the ventilatory and carotid-body phenotype of a mouse model of CP, using whole-body plethysmography, immunohistochemistry, and electron microscopy. In keeping with studies in humans, CP mice had elevated ventilation in euoxia and a significantly exaggerated AHVR when exposed to 10% oxygen, with or without the addition of 3% carbon dioxide. Carotid-body immunohistochemistry demonstrated marked hyperplasia of the oxygen-sensing type I cells, and the cells themselves appeared enlarged with more prominent nuclei. This hypertrophy was confirmed by electron microscopy, which also revealed that the type I cells contained an increased number of mitochondria, enlarged dense-cored vesicles, and markedly expanded rough endoplasmic reticulum. The morphological and ultrastructural changes seen in the CP mouse carotid body are strikingly similar to those observed in animals exposed to chronic hypoxia. Our study demonstrates that the HIF pathway plays a major role, not only in regulating both euoxic ventilatory control and the sensitivity of the response to hypoxia, but also in determining the morphology of the carotid body.

  4. A comparative evaluation of different supraglottic ventilatory devices during general anesthesia with controlled ventilation: A pilot study

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    Ahmed A. Abd El Aziz

    2014-10-01

    Conclusions: We concluded that the I-gel, PLMA and SLIPA are effective ventilatory devices during controlled ventilation, without major complications. I-gel offers advantage over PLMA and SLIPA in being less manipulation needed during placement, less air leak, less postoperative sore throat and less in blood stained to the device after its removal in comparison with PLMA and SLIPA.

  5. Rh protein expression in branchial neuroepithelial cells, and the role of ammonia in ventilatory control in fish.

    Science.gov (United States)

    Zhang, Li; Michele Nawata, C; De Boeck, Gudrun; Wood, Chris M

    2015-08-01

    Bill Milsom has made seminal contributions to our understanding of ventilatory control in a wide range of vertebrates. Teleosts are particularly interesting, because they produce a 3rd, potentially toxic respiratory gas (ammonia) in large amounts. Fish are well known to hyperventilate under high environmental ammonia (HEA), but only recently has the potential role of ammonia in normal ventilatory control been investigated. It is now clear that ammonia can act directly as a ventilatory stimulant in trout, independent of its effects on acid-base balance. Even in ureotelic dogfish sharks, acute elevations in ammonia cause increases in ventilation. Peripherally, the detection of elevated ammonia resides in gill arches I and II in trout, and in vitro, neuroepithelial cells (NECs) from these arches are sensitive to ammonia, responding with elevations in intracellular Ca(2+) ([Ca(2+)]i). Centrally, hyperventilatory responses to ammonia correlate more closely with concentrations of ammonia in the brain than in plasma or CSF. After chronic HEA exposure, ventilatory responsiveness to ammonia is lost, associated with both an attenuation of the [Ca(2+)]i response in NECs, and the absence of elevation in brain ammonia concentration. Chronic exposure to HEA also causes increases in the mRNA expression of several Rh proteins (ammonia-conductive channels) in both brain and gills. "Single cell" PCR techniques have been used to isolate the individual responses of NECs versus other gill cell types. We suggest several circumstances (post-feeding, post-exercise) where the role of ammonia as a ventilatory stimulant may have adaptive benefits for O2 uptake in fish.

  6. Heat and moisture exchanger: importance of humidification in anaesthesia and ventilatory breathing system.

    Science.gov (United States)

    Parmar, Vandana

    2008-08-01

    Adequate humidification is vital to maintain homeostasis of the airway. Heat and moisture exchangers conserve some of the exhaled water, heat and return them to inspired gases. Many heat and moisture exchangers also perfom bacterial/viral filtration and prevent inhalation of small particles. Heat and moisture exchangers are also called condenser humidifier, artificial nose, etc. Most of them are disposable devices with exchanging medium enclosed in a plastic housing. For adult and paediatric age group different dead space types are available. Heat and moisture exchangers are helpful during anaesthesia and ventilatory breathing system. To reduce the damage of the upper respiratory tract through cooling and dehydration inspiratory air can be heated and humidified, thus preventing the serious complications.

  7. Signaling at the cell surface in the circulatory and ventilatory systems

    CERN Document Server

    Thiriet, Marc

    2012-01-01

    The volumes in this authoritative series present a multidisciplinary approach to modeling and simulation of flows in the cardiovascular and ventilatory systems, especially multiscale modeling and coupled simulations. The cardiovascular and respiratory systems are tightly coupled, as their primary function is to supply oxygen to and remove carbon dioxide from the body's cells. Because physiological conduits have deformable and reactive walls, macroscopic flow behavior and prediction must be coupled to nano- and microscopic events in a corrector scheme of regulated mechanisms when the vessel lumen caliber varies markedly. Therefore, investigation of flows of blood and air in physiological conduits requires an understanding of the biology, chemistry, and physics of these systems together with the mathematical tools to describe their functioning. Volume 3 is devoted to the set of mediators of the cell surface, especially ion and molecular carriers and catalytic receptors that, once liganded and activated, initiat...

  8. Ventilatory management of respiratory failure in patients with severe Guillain-Barré syndrome

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    Aggarwal A

    2003-04-01

    Full Text Available Guillain-Barré syndrome (GBS is the commonest peripheral neuropathy causing ventilatory failure, and 10-30% patients may require respiratory support. Records of 11 adult patients of GBS in respiratory failure, admitted to the Respiratory Intensive Care Unit (RICU of our institute for mechanical ventilation over a four-year period, were studied. Six patients received intravenous immunoglobulin. The median duration of mechanical ventilation was 38 days. Seven patients underwent tracheostomy. Four patients were ventilated for less than 2 weeks and 3 for more than 2 months each. Seven developed ventilator-associated pneumonia and/or sepsis. Three patients died in, and two shortly after discharge from RICU; all had systemic problems or complications of hospitalization.

  9. The Carotid Body Does Not Mediate the Acute Ventilatory Effects of Leptin.

    Science.gov (United States)

    Olea, E; Ribeiro, M J; Gallego-Martin, T; Yubero, S; Rigual, R; Masa, J F; Obeso, A; Conde, S V; Gonzalez, C

    2015-01-01

    Leptin is a hormone produced mostly in adipose tissue and playing a key role in the control of feeding and energy expenditure aiming to maintain a balance between food intake and metabolic activity. In recent years, it has been described that leptin might also contributes to control ventilation as the administration of the hormone reverses the hypoxia and hypercapnia commonly encountered in ob/ob mice which show absence of the functional hormone. In addition, it has been shown that the carotid body (CB) of the rat expresses leptin as well as the functional leptin-B receptor. Therefore, the possibility exists that the ventilatory effects of leptin are mediated by the CB chemoreceptors. In the experiments described below we confirm the stimulatory effect of leptin on ventilation, finding additionally that the CB does not mediate the instant to instant control of ventilation.

  10. Ventilatory function assessment in safety pharmacology: optimization of rodent studies using normocapnic or hypercapnic conditions.

    Science.gov (United States)

    Goineau, Sonia; Rompion, Sonia; Guillaume, Philippe; Picard, Sandra

    2010-09-15

    Although the whole body plethysmography for unrestrained animals is the most widely used method to assess the respiratory risk of new drugs in safety pharmacology, non-appropriate experimental conditions may mask deleterious side effects of some substances. If stimulant or bronchodilatory effects can be easily evidenced in rodents under standard experimental conditions, i.e. normal air breathing and diurnal phase, drug-induced respiratory depression remains more difficult to detect. This study was aimed at comparing the responsiveness of Wistar rats, Duncan Hartley guinea-pigs or BALB/c mice to the respiratory properties of theophylline (50 or 100 mg/kg p.o.) or morphine (30 mg/kg i.p.) under varying conditions (100% air versus 5% CO2-enriched air, light versus dark day phase), in order to select the most appropriate experimental conditions to each species for safety airway investigations. Our results showed that under normocapnia the ventilatory depressant effects of morphine can be easily evidenced in mice, slightly observed in guinea-pigs and not detected in rats in any day phase. Slight hypercapnic conditions enhanced the responsiveness of rats to morphine but not that of guinea-pigs and importantly they did not blunt the airway responsiveness of rats to the stimulation and bronchodilation evoked by theophylline, the most widely used reference agent in safety pharmacology studies. In conclusion, hypercapnic conditions associated with the non-invasive whole body plethysmography should be considered for optimizing the assessment of both the ventilatory depressant potential of morphine-like substances or the respiratory stimulant effects of new drugs in the rat, the most extensively used species in rodent safety and toxicological investigations.

  11. Chronic overexpression of cerebral Epo improves the ventilatory response to acute hypoxia during the postnatal development.

    Science.gov (United States)

    Caravagna, Céline; Gasser, Edith M Schneider; Ballot, Orlane; Joseph, Vincent; Soliz, Jorge

    2015-08-01

    Clinicians observed that the treatment of premature human newborns for anemia with erythropoietin (Epo) also improved their respiratory autonomy. This observation is in line with our previous in vitro studies showing that acute and chronic Epo stimulation enhances fictive breathing of brainstem-spinal cord preparations of postnatal day 3-4 mice during hypoxia. Furthermore, we recently reported that the antagonization of the cerebral Epo (by using the soluble Epo receptor; sEpoR) significantly reduced the basal ventilation and the hypoxic ventilatory response of 10 days old mice. In this study, we used transgenic (Tg21) mice to investigate the effect of the chronic cerebral Epo overexpression on the modulation of the normoxic and hypoxic ventilatory drive during the post-natal development. Ventilation was evaluated by whole body plethysmography at postnatal ages 3 (P3), 7 (P7), 15 (P15) and 21 (P21). In addition Epo quantification was performed by RIA and mRNA EpoR was evaluated by qRT-PCR. Our results showed that compared to control animals the chronic Epo overexpression stimulates the hypoxic (but not the normoxic) ventilation assessed as VE/VO2 at the ages of P3 and P21. More interestingly, we observed that at P7 and P15 the chronic Epo stimulation of ventilation was attenuated by the down regulation of the Epo receptor in brainstem areas. We conclude that Epo, by stimulating ventilation in brainstem areas crucially helps tolerating physiological (e.g., high altitude) and/or pathological (e.g., respiratory disorders, prematurity, etc.) oxygen deprivation at postnatal ages.

  12. Immediate effect of suryanadi pranayama on pulmonary function (ventilatory volumes and capacities in healthy volunteers

    Directory of Open Access Journals (Sweden)

    Shravya Keerthi G, Hari Krishna Bandi, Suresh M, Mallikarjuna Reddy N

    2013-10-01

    Full Text Available Objectives: we found only effects of at least a short term practice extended over a period of a few days to weeks of pranayama (alternate nostril breathing rather than acute effects of unilateral right nostril breathing (suryanadi pranayama. Keeping this in mind the present study was designed to test the hypothesis that 10 min. of right nostril breathing have any immediate effect on ventilatory volumes and capacities in healthy volunteers. Methodology: Forced vital capacity (FVC, Forced expiratory volume in the first second (FEV1, Forced expiratory volume percent (FEV1/FVC%, Peak expiratory flow rate (PEFR, Forced expiratory flow25-75% (FEF25-75%, Maximum voluntary ventilation (MVV, Slow vital capacity (SVC, Expiratory reserve volume (ERV, Inspiratory reserve volume (IRV and Tidal volume (TV were recorded before and after Surya Nadi Pranayama. Results & Conclusion: There was a significant increase in FVC (p<0.0001, FEV1 (p<0.0007, PEFR (p<0.0001, FEF25-75% (p<0.0001, MVV (p<0.0001, SVC (p<0.0001, ERV (0.0006, IRV (p<0.0001 and TV (0.0055 after suryanadi pranayama. The immediate effect of suryanadi pranayama practice showed alleviation of ventilatory capacities and volumes. Any practice that increases PEFR and FEF25–75% is expected to retard the development of COPD’s. The increase in PEFR, vital capacities and flow rates by suryanadi pranayama practice obviously offers an increment in respiratory efficiency and it can be advocated to the patients of early bronchitis and as a preventive measure for COPD.

  13. Ventilatory support and pharmacological treatment of patients with central apnoea or hypoventilation during sleep

    Directory of Open Access Journals (Sweden)

    D. Pevernagie

    2007-12-01

    Full Text Available The concept of central sleep apnoea or hypoventilation encompasses hypercapnic central hypoventilation, such as obesity hypoventilation syndrome and eucapnic or hypocapnic central sleep apnoea. Among subjects with eucapnic or hypocapnic central sleep apnoea, several therapeutic options are available for those with Cheyne–Stokes respiration (CSR. CSR is frequent in patients with New York Heart Association stage III and IV chronic heart failure, and in various neurological disorders. In these patients, treatment modalities include optimising cardiac condition and drugs, such as theophylline, acetazolamide and/or oxygen. Ventilatory support, such as nasal continuous positive airway pressure (CPAP, bi-level pressure support, or adaptive servo-ventilation (ASV, has been shown to improve CSR in patients with cardiac failure; however, convincing evidence that nasal CPAP improves life expectancy in these patients is lacking. Nevertheless, the treatment of associated obstructive sleep-disordered breathing is indicated per se, as it may improve cardiac function. There is currently no proof that bi-level ventilation is superior to nasal CPAP. The few available studies that have focused on ASV have shown satisfactory control of CSR in cardiac failure patients. While ASV is not a first-line treatment choice, it appears to be superior to oxygen, CPAP and bi-level pressure ventilation in controlling the apnoea/hypopnea index and probably sleep fragmentation. As yet there are no data on mortality and, as such, firm conclusions cannot be drawn as to the role of ASV in the management of cardiac failure patients suffering from CSR. Obesity-related hypoventilation has increased dramatically over recent decades due to the epidemic increase in obesity in the developed countries. Obesity hypoventilation syndrome predisposes to the development of pulmonary hypertension and cor pulmonale. Noninvasive home ventilation is increasingly applied in obese patients with

  14. SIDS Family Adjustment Scale: A Method of Assessing Family Adjustment to Sudden Infant Death Syndrome.

    Science.gov (United States)

    May, Harold J.; Breme, Frederick J.

    1982-01-01

    Discusses Sudden Infant Death Syndrome (SIDS) and the family's resultant grief process. Explores SIDS as a family crisis, and by identifying the psychological factors or tasks pertinent to family adjustment, proposes a SIDS Family Adjustment Scale which assists in recognizing adaptive and maladaptive grief responses. (Author)

  15. 24 CFR 891.785 - Adjustment of utility allowances.

    Science.gov (United States)

    2010-04-01

    ... 24 Housing and Urban Development 4 2010-04-01 2010-04-01 false Adjustment of utility allowances... Handicapped Families and Individuals-Section 162 Assistance § 891.785 Adjustment of utility allowances. In... adjustment of utility allowances provided in § 891.440 apply....

  16. Ventilatory requirements of quadriceps resistance training in people with COPD and healthy controls

    Directory of Open Access Journals (Sweden)

    Houchen-Wolloff L

    2014-06-01

    Full Text Available Linzy Houchen-Wolloff,1 Carolyn J Sandland,1 Samantha L Harrison,1 Manoj K Menon,1 Mike D Morgan,1 Michael C Steiner,1 Sally J Singh1,21Centre for Exercise and Rehabilitation Science, Respiratory Biomedical Research Unit, Glenfield Hospital, Leicester, UK; 2Faculty of Health and Life Sciences, Coventry University, Coventry, UKBackground: It is proposed that resistance training (RT does not activate the cardiopulmonary system to the same extent as whole-body exercise. This is important for patients with chronic obstructive pulmonary disease (COPD who are ventilatory limited.Objective: The aim was to assess the ventilatory response to an isokinetic quadriceps RT program in people with COPD and healthy controls.Design: Observational.Registration number: ISRCTN22764439.Setting: Outpatient, university teaching hospital.Participants and outcome measures: People with COPD (n=14 and healthy controls (n=11 underwent breath-by-breath analysis of their ventilation during an RT session (five sets of 30 maximal knee extensions at 180°/sec. Subjects performed a maximal cycle ergometry test (CET at baseline. Peak ventilation (VE; L/min and oxygen consumption (VO2; mL/kg/min were collected. The same system measured VO2 and VE during the RT session. Parameters are presented as a percentage of the maximal CET. Isokinetic workload, symptom scores, heart rate (HR, and oxygen saturation were documented post-training.Results: People with COPD worked at higher percentages of their maximal capacity than controls (mean range between sets 1–5 for VO2 =49.1%–60.1% [COPD], 45.7%–51.43% [controls] and for VE =57.6%–72.2% [COPD], 49.8%–63.6% [controls], although this was not statistically significant (P>0.1 in all cases. In absolute terms, the difference between groups was only significant for actual VO2 on set 2 (P<0.05. Controls performed more isokinetic work than patients with COPD (P<0.05. Median Borg symptom scores after RT were the same in both groups (3

  17. Acute effects of different inspiratory efforts on ventilatory pattern and chest wall compartmental distribution in elderly women.

    Science.gov (United States)

    Muniz de Souza, Helga; Rocha, Taciano; Campos, Shirley Lima; Brandão, Daniella Cunha; Fink, James B; Aliverti, Andrea; de Andrade, Armele Dornelas

    2016-06-15

    It is not completely described how aging affect ventilatory kinematics and what are the mechanisms adopted by the elderly population to overcome these structural modifications. Given this, the aim was to evaluate the acute effects of different inspiratory efforts on ventilatory pattern and chest wall compartmental distribution in elderly women. Variables assessed included: tidal volume (Vt), total chest wall volume (Vcw), pulmonary rib cage (Vrcp%), abdominal rib cage (Vrca%) and abdominal compartment (Vab%) relative contributions to tidal volume. These variables were assessed during quiet breathing, maximal inspiratory pressure maneuver (MIP), and moderate inspiratory resistance (MIR; i.e., 40% of MIP). 22 young women (age: 23.9 ± 2.5 years) and 22 elderly women (age: 68.2 ± 5.0 years) participated to this study. It was possible to show that during quiet breathing, Vab% was predominant in elderly (pelderly (p=0.249). When MIP was imposed, both groups presented a predominance of Vrcp%. In conclusion, there are differences in abdominal kinematics between young and elderly women during different inspiratory efforts. In elderly, during moderate inspiratory resistance, the pattern is beneficial, deep, and slow. Although, during maximal inspiratory resistance, the ventilatory pattern seems to predict imminent muscle fatigue.

  18. Does amifostine reduce metabolic rate? Effect of the drug on gas exchange and acute ventilatory hypoxic response in humans.

    Science.gov (United States)

    Pandit, Jaideep J; Allen, Caroline; Little, Evelyn; Formenti, Federico; Harris, Adrian L; Robbins, Peter A

    2015-04-16

    Amifostine is added to chemoradiation regimens in the treatment of many cancers on the basis that, by reducing the metabolic rate, it protects normal cells from toxic effects of therapy. We tested this hypothesis by measuring the metabolic rate (by gas exchange) over 255 min in 6 healthy subjects, at two doses (500 mg and 1000 mg) of amifostine infused over 15 min at the start of the protocol. We also assessed the ventilatory response to six 1 min exposures to isocapnic hypoxia mid-protocol. There was no change in metabolic rate with amifostine as measured by oxygen uptake (p = 0.113). However in carbon dioxide output and respiratory quotient, we detected a small decline over time in control and drug protocols, consistent with a gradual change from carbohydrate to fat metabolism over the course of the relatively long study protocol. A novel result was that amifostine (1000 mg) increased the mean ± SD acute hypoxic ventilatory response from 12.4 ± 5.1 L/min to 20.3 ± 11.9 L/min (p = 0.045). In conclusion, any cellular protective effects of amifostine are unlikely due to metabolic effects. The stimulatory effect on hypoxic ventilatory responses may be due to increased levels of hypoxia inducible factor, either peripherally in the carotid body, or centrally in the brain.

  19. Cerebrovascular and ventilatory responses to acute isocapnic hypoxia in healthy aging and lung disease: effect of vitamin C.

    Science.gov (United States)

    Hartmann, Sara E; Waltz, Xavier; Kissel, Christine K; Szabo, Lian; Walker, Brandie L; Leigh, Richard; Anderson, Todd J; Poulin, Marc J

    2015-08-15

    Acute hypoxia increases cerebral blood flow (CBF) and ventilation (V̇e). It is unknown if these responses are impacted with normal aging, or in patients with enhanced oxidative stress, such as (COPD). The purpose of the study was to 1) investigate the effects of aging and COPD on the cerebrovascular and ventilatory responses to acute hypoxia, and 2) to assess the effect of vitamin C on these responses during hypoxia. In 12 Younger, 14 Older, and 12 COPD, we measured peak cerebral blood flow velocity (V̄p; index of CBF), and V̇e during two 5-min periods of acute isocapnic hypoxia, under conditions of 1) saline-sham; and 2) intravenous vitamin C. Antioxidants [vitamin C, superoxide dismutase (SOD), glutathione peroxidase, and catalase], oxidative stress [malondialdehyde (MDA) and advanced protein oxidation product], and nitric oxide metabolism end products (NOx) were measured in plasma. Following the administration of vitamin C, vitamin C, SOD, catalase, and MDA increased, while NOx decreased. V̄p and V̇e sensitivity to hypoxia was reduced in Older by ∼60% (P 0.05). Vitamin C did not have an effect on the hypoxic V̇e response but selectively decreased the V̄p sensitivity in Younger only. These findings suggest a reduced integrative reflex (i.e., cerebrovascular and ventilatory) during acute hypoxemia in healthy older adults. Vitamin C does not appear to have a large influence on the cerebrovascular or ventilatory responses during acute hypoxia.

  20. Heart rate response during a simulated Olympic boxing match is predominantly above ventilatory threshold 2: a cross sectional study.

    Science.gov (United States)

    de Lira, Claudio Andre Barbosa; Peixinho-Pena, Luiz Fernando; Vancini, Rodrigo Luiz; de Freitas Guina Fachina, Rafael Júlio; de Almeida, Alexandre Aparecido; Andrade, Marília Dos Santos; da Silva, Antonio Carlos

    2013-01-01

    The present study aimed to describe heart rate (HR) responses during a simulated Olympic boxing match and examine physiological parameters of boxing athletes. Ten highly trained Olympic boxing athletes (six men and four women) performed a maximal graded exercise test on a motorized treadmill to determine maximal oxygen uptake (52.2 mL · kg(-1) · min(-1) ± 7.2 mL · kg(-1) · min(-1)) and ventilatory thresholds 1 and 2. Ventilatory thresholds 1 and 2 were used to classify the intensity of exercise based on respective HR during a boxing match. In addition, oxygen uptake (V̇O2) was estimated during the match based on the HR response and the HR-V̇O2 relationship obtained from a maximal graded exercise test for each participant. On a separate day, participants performed a boxing match lasting three rounds, 2 minutes each, with a 1-minute recovery period between each round, during which HR was measured. In this context, HR and V̇O2 were above ventilatory threshold 2 during 219.8 seconds ± 67.4 seconds. There was an increase in HR and V̇O2 as a function of round (round 3 boxing practitioners and other athletes.

  1. Preliminary investigation into the ventilatory effects of midazolam in isoflurane-anaesthetised goats

    Directory of Open Access Journals (Sweden)

    George F. Stegmann

    2012-04-01

    Full Text Available The ventilatory effects of intravenous midazolam (MDZ were evaluated in isoflurane- anaesthetised goats. Eight female goats aged 2–3 years were fasted from food and water for 12 h. Anaesthesia was then induced using a face mask with isoflurane in oxygen, whilst the trachea was intubated with a cuffed tracheal tube and anaesthesia maintained with isoflurane at 1.5% end-tidal concentration. Ventilation was spontaneous. The goats were treated with either a saline placebo (PLC or MDZ intravenously at 0.2 mg/kg. Analysis of variance for repeated measures was used for the analysis of data. Significance was taken at the 0.05 level. Differences between treatments were not statistically significant (p > 0.05 for tidal volume, ventilation rate, tidal volume/kg (VT/kg and end-tidal carbon dioxide partial pressure. Within treatments, VT and VT/kg differed 5 min after MDZ administration; this was statistically significant (p < 0.05. The occurrence of apnoea in the MDZ-treated goats was statistically significant (p = 0.04 compared with the PLC treated goats. Intravenous MDZ at 0.2 mg/kg administered to isoflurane-anaesthetised goats may result in transient apnoea and a mild decrease in VT and VT/kg.

  2. Effects of a prior short simulated training session on the subsequent occurrence of ventilatory thresholds.

    Science.gov (United States)

    Guilhem, Gaël; Dorel, Sylvain; Hug, Francois

    2009-03-01

    The concept of ventilatory thresholds (VTs) has been shown to be particularly useful to prescribe exercise intensities, yet, to date no study has examined the effects of previous submaximal exercise (i.e. a simulated training session) on the subsequent occurrence of VTs. We designed the present study to test the hypothesis that a previous short simulated training session induces an earlier VTs occurrence. Thirteen trained subjects perfomed two classical incremental tests on a cycle ergometer. The two tests were separated by a time period of 2-5 days, and the second test was preceded by a 34-min simulated training session. The first and second VTs (VT(1) and VT(2), respectively) were detected and expressed in their corresponding values of time, V O(2), and power output. The simulated training session did not modify VT(1) occurrence. In contrast, VT(2) was influenced by the simulated training session, showing a significant earlier occurence when VT(2) was expressed in time [-42 (-72; -13)s] and in power output [-15 (-25; -5)W]. Maximal power tolerated (MPT) was also significantly reduced by the previous exercise [-17 (-27; -7)W]. As a consequence, training intensities based on power output (associated with VT(2) or in %MPT) would be overestimated (i.e. higher metabolic state) after a short period of training session. Thus, doubt is cast on the pertinence of using the power output (or running speed by extension) for prescription of exercise during prolonged training sessions.

  3. Ventilatory behaviors of the toad Bufo marinus revealed by coherence analysis

    Directory of Open Access Journals (Sweden)

    F. C. Coelho

    Full Text Available Breathing in amphibians is a remarkably complex behavior consisting of irregular breaths that may be taken singly or in bouts that are used to deflate and inflate the lungs. The valves at the two outlets of the buccal cavity (nares and glottis need to be finely controlled throughout the bout for the expression of these complex respiratory behaviors. In this study, we use a technique based on the calculation of the coherence spectra between respiratory variables (buccal pressure; narial airflow; and lung pressure. Coherence was also used to quantify the effects of chemoreceptor and pulmonary mechanoreceptor input on narial and glottal valve behavior on normoxic, hypoxic, and hypercapnic toads with both intact and bilaterally sectioned pulmonary vagi. We found a significant reduction in narial coherence in hypoxic vagotomized toads indicating that pulmonary mechanoreceptor feedback modulates narial opening duration. An unexpectedly high coherence between Pl and Pb during non-respiratory buccal oscillations in hypercapnic toads indicated more forceful use of the buccal pump. We concluded that the coherence function reveals behaviors that are not apparent through visual inspection of ventilatory time series.

  4. Hypoxic ventilatory sensitivity in men is not reduced by prolonged hyperoxia (Predictive Studies V and VI)

    Science.gov (United States)

    Gelfand, R.; Lambertsen, C. J.; Clark, J. M.; Hopkin, E.

    1998-01-01

    Potential adverse effects on the O2-sensing function of the carotid body when its cells are exposed to toxic O2 pressures were assessed during investigations of human organ tolerance to prolonged continuous and intermittent hyperoxia (Predictive Studies V and VI). Isocapnic hypoxic ventilatory responses (HVR) were determined at 1.0 ATA before and after severe hyperoxic exposures: 1) continuous O2 breathing at 1.5, 2.0, and 2.5 ATA for 17.7, 9.0, and 5.7 h and 2) intermittent O2 breathing at 2.0 ATA (30 min O2-30 min normoxia) for 14.3 O2 h within 30-h total time. Postexposure curvature of HVR hyperbolas was not reduced compared with preexposure controls. The hyperbolas were temporarily elevated to higher ventilations than controls due to increments in respiratory frequency that were proportional to O2 exposure time, not O2 pressure. In humans, prolonged hyperoxia does not attenuate the hypoxia-sensing function of the peripheral chemoreceptors, even after exposures that approach limits of human pulmonary and central nervous system O2 tolerance. Current applications of hyperoxia in hyperbaric O2 therapy and in subsea- and aerospace-related operations are guided by and are well within these exposure limits.

  5. POSTURAL CONTROL AFTER A PROLONGED TREADMILL RUN AT INDIVIDUAL VENTILATORY AND ANAEROBIC THRESHOLD

    Directory of Open Access Journals (Sweden)

    Laura Guidetti

    2011-09-01

    Full Text Available The objective of the study was to verify whether young males' balance was affected by 30min prolonged treadmill running (TR at individual ventilatory (IVT and anaerobic (IAT thresholds in recovery time. The VO2max, IAT and IVT during an incremental TR were determined. Mean displacement amplitude (Acp and velocity (Vcp of center of pressure were recorded before (pre and after (0min post; 5min post; and 10min post prolonged TR at IAT and IVT, through posturographic trials performed with eyes open (EO and closed (EC. Significant differences between IVT and IAT for Vcp, between EO and EC for Acp and Vcp, were observed. The IAT induced higher destabilizing effect when postural trials were performed with EC. The IVT intensity produced also a destabilizing effect on postural control immediately after exercise. An impairment of postural control after prolonged treadmill running exercise at IVT and IAT intensity was showed. However, destabilizing effect on postural control disappeared within 10min after IAT intensity and within 5min after IVT intensity

  6. Prediction VO2max during cycle ergometry based on submaximal ventilatory indicators.

    Science.gov (United States)

    Nunes, Rodolfo Alkmim Moreira; Vale, Rodrigo Gomes de Souza; Simão, Roberto; de Salles, Belmiro Freitas; Reis, Victor Machado; Novaes, Jefferson da Silva; Miranda, Humberto; Rhea, Matthew R; Medeiros, Aldo da Cunha

    2009-09-01

    There are several equations to predict maximum oxygen consumption (VO2max) from ergometric test variables on different ergometers. However, a similar equation using ventilatory thresholds of ergospirometry in a submaximal test on a cycle ergometer is unavailable. The aim of the present study was to assess the accuracy of VO2max prediction models based on indicators of submaximal effort. Accordingly, 4,640 healthy, nonathlete women ages 20 years and older volunteered to be tested on a cycle ergometer using a maximum incremental protocol. The subjects were randomly assigned to 2 groups: group A (estimation) and group B (validation). From the independent variables of weight in kilograms, the second workload threshold (WT2), and heart rate of the second threshold (HRT2), it was possible to build a multiple linear regression model to predict maximal oxygen consumption (VO2max = 40.302 - 0.497 [Weight] - 0.001 [HRT2] + 0.239 [WT2] in mL O2/kg/min(-1); r = 0.995 and standard error of the estimate [SEE] = 0.68 mL O2/kg/min(-1)). The cross-validation method was used in group B with group A serving as the basis for building the model and the validation dataset. The results showed that, in healthy nonathlete women, it is possible to predict VO2max with a minimum of error (SEE = 1.00%) from submaximal indicators obtained in an incremental test.

  7. A new ventilatory threshold equation for aerobically trained men and women.

    Science.gov (United States)

    Malek, Moh H; Coburn, Jared W

    2009-04-01

    The purposes of the present study were to (i) modify previously published ventilatory threshold (VT) equations using the constant error (CE) values for aerobically trained individuals from a recent study; (ii) cross-validate the modified equations to determine their accuracy for estimating VT in aerobically trained individuals; (iii) derive a new non-exercise based equation for estimating VT in aerobically trained individuals if the modified equations are found to be inaccurate; and (iv) cross-validate the new VT equation using the Predicted REsidual Sum of Squares (PRESS) statistic and an independent sample of aerobically trained individuals. Two hundred and eight (n = 208) aerobically trained men and women (mean +/- SD: age = 38.8 +/- 10.4 year) performed a maximal incremental test on a cycle ergometer to determine the observed VT. The predicted VT values from seven published equations were compared with the observed VT by examining the CE, standard error of estimate, validity coefficient (r), and total error (TE). Cross-validation of the modified equations resulted in high %TE values. Therefore, a new VT equation was derived. Cross-validation of this equation on an independent sample of 72 subjects resulted in a low %TE value. The new model is recommended over previous models for estimating VT in aerobically trained individuals.

  8. Double product break point estimates ventilatory threshold in individuals with type 2 diabetes.

    Science.gov (United States)

    Victor de Sousa, Caio; Sales, Marcelo Magalhães; Aguiar, Samuel da Silva; Boullosa, Daniel Alexandre; Rosa, Thiago Dos Santos; Baldissera, Vilmar; Simões, Herbert Gustavo

    2016-06-01

    [Purpose] To verify the identification of the anaerobic threshold through the double product breakpoint (DPBP) method for individuals with type 2 diabetes. [Subjects and Methods] Nine individuals with T2D (7 females; age=63.2 ± 8.9 y) and 10 non-diabetic (ND) (7 females; age=58.3 ± 7.8 y) performed an incremental exercise test on a cycle ergometer. Heart rate (HR), blood pressure (BP) and expired gas were measured at the end of each stage. The ventilatory threshold (VT) and DPBP were considered as the exercise intensities above which an over proportional increases in VE and DP were observed in relation to increasing workload. [Results] No differences were observed between the workloads, HR and VO2 corresponding to the AT identified respectively by VT and DPBP. For the T2D, strong correlations between VT and DBPB workloads (r=0.853), HR (r=0.714), and VO2 (r=0.863) were found. These relationships were similar to those found for the control group (r=0.923; r=0.881; and r=0.863, respectively). [Conclusion] These results demonstrate that the DPBP enables for the prediction of AT and correlated well the VT in both the T2D and ND participants.

  9. Annual Adjustment Factors

    Data.gov (United States)

    Department of Housing and Urban Development — The Department of Housing and Urban Development establishes the rent adjustment factors - called Annual Adjustment Factors (AAFs) - on the basis of Consumer Price...

  10. Lack of correlation between the ventilatory response to CO2 and lung function impairment in myotonic dystrophy patients: evidence for a dysregulation at central level.

    Science.gov (United States)

    Poussel, Mathias; Thil, Catherine; Kaminsky, Pierre; Mercy, Magalie; Gomez, Emmanuel; Chaouat, Ari; Chabot, François; Chenuel, Bruno

    2015-05-01

    Myotonic dystrophy Type 1 (DM1) is the most common muscular dystrophy in adults. Respiratory failure is common but clinical findings support a dysregulation of the control of breathing at central level, furthermore contributing to alveolar hypoventilation independently of the severity of respiratory weakness. We therefore intended to study the relationship between the ventilatory response to CO2 and the impairment of lung function in DM1 patients. Sixty-nine DM1 patients were prospectively investigated (43.5 ± 12.7 years). Systematic pulmonary lung function evaluation including spirometry, plethysmography, measurements of respiratory muscle strength, arterial blood gas analysis and ventilatory response to CO2 were performed. Thirty-one DM1 patients (45%) presented a ventilatory restriction, 38 (55%) were hypoxaemic and 15 (22%) were hypercapnic. Total lung capacity decline was correlated to hypoxaemia (p = 0.0008) and hypercapnia (p = 0.0013), but not to a decrease in ventilatory response to CO2 (p = 0.194). Ventilatory response to CO2 was reduced to 0.85 ± 0.67 L/min/mmHg and not correlated to respiratory muscle weakness. Ventilatory response to CO2 was neither different among restricted/non-restricted patients (p = 0.2395) nor among normoxaemic/hypoxaemic subjects (p = 0.6380). The reduced ventilatory response to CO2 in DM1 patients appeared independent of lung function impairment and respiratory muscle weakness, suggesting a central cause of CO2 insensitivity.

  11. Differences in Ventilatory Threshold for Exercise Prescription in Outpatient Diabetic and Sarcopenic Obese Subjects

    Directory of Open Access Journals (Sweden)

    Gian Pietro Emerenziani

    2016-01-01

    Full Text Available Aim of the study was to examine cardiorespiratory parameters at individual ventilatory threshold (IVT and peak exercise capacity (V˙O2peak in outpatient diabetic and sarcopenic obese subjects. Seventeen obese subjects (BMI: 36.6±4.1 kg·m−1 and sixteen SO subjects (BMI: 37.0±7.3 kg·m−1 were compared with sixteen T2DM subjects (BMI: 37.7±5.6 kg·m−1. All groups performed an incremental exercise test on a treadmill according to their physical ability. V˙O2peak, %HRmax, and maximal metabolic equivalent (METmax were evaluated at maximal effort. Moreover, V˙O2ivt, %V˙O2peak, %HRmax, %HRR, ΔHR, and METivt were assessed at IVT. No significant differences were found in any physiological parameters at maximal effort (V˙O2peak, %HRmax, and METmax in all groups. On the contrary, V˙O2ivt, %V˙O2peak, %HRmax, %HRR, ΔHR, and METivt were significantly lower in T2DM subjects as compared to OB and SO subjects at IVT (p<0.05. Our results show that while at maximal effort there are no differences among groups, at IVT the physiological parameters are lower in T2DM subjects than in OB and SO subjects. Therefore, due to the differences observed in the groups, we suggest usng the IVT as a useful parameter to prescribe aerobic exercise in obese with sarcopenia or diabetes mellitus conditions.

  12. Associative conditioning with leg cycling and inspiratory resistance enhances the early exercise ventilatory response in humans.

    Science.gov (United States)

    Turner, Duncan; Stewart, Jamie D

    2004-12-01

    Repeated trials of hypercapnic exercise [deltaPET CO2 = 7 (1) mmHg] augment the increase in inspired minute ventilation and tidal volume (V(T)) in the early phase of subsequent trials of unencumbered exercise alone. The increase in V(T) in the first 20 s of exercise was correlated to the increase in V(T) evoked during hypercapnic exercise trials, suggesting that the evoked increase in V(T) during conditioning may be a factor in mediating associative conditioning. To test this hypothesis, inspiratory resistive loading (IRL) was employed to evoke an increase in V(T) [deltaV(T) = 0.4 (0.1) I(BTPS)] during conditioning exercise trials [IRL + EX; deltaP(ET)CO2 = 2 (l) mmHg]. IRL + EX associative conditioning elicited a significant augmentation of the early minute ventilation (+46%) and V(T) (+100%) responses to subsequent unencumbered exercise. The latter was correlated to the evoked increase in V(T) during associative conditioning with IRL + EX. The results support the hypothesis that an evoked increase in V(T) during associative conditioning could be a factor in eliciting long-term modulation of minute ventilation in subsequent unencumbered exercise. The results further indicated that the modulation of ventilation early in exercise is not due to sensitisation to repeated trials of either IRL or exercise alone. Associative conditioning may shape the ventilatory response to exercise through a process of motor learning. Data are presented as mean (SEM) unless otherwise stated.

  13. Maternal hypoxic ventilatory response, ventilation, and infant birth weight at 4,300 m.

    Science.gov (United States)

    Moore, L G; Brodeur, P; Chumbe, O; D'Brot, J; Hofmeister, S; Monge, C

    1986-04-01

    To test the hypothesis that increased hypoxic ventilatory responsiveness (HVR) raised maternal ventilation and arterial oxygenation during high-altitude pregnancy and related to the birth weight of the offspring, we studied 21 residents of Cerro de Pasco, Peru (4,300 m), while eight of them were 36 +/- 0 wk pregnant and 15 of them 13 +/- 0 wk postpartum. HVR was low in the nonpregnant women (mean +/- SE shape parameter A = 23 +/- 8) but increased nearly fourfold with pregnancy (A = 87 +/- 17). The increase in HVR appeared to account for the 25% rise in resting ventilation with pregnancy (delta VE observed = 2.4 +/- 0.7 l/min BTPS vs. delta VE predicted from delta HVR = 2.6 +/- 1.7 l/min BTPS, P = NS). Hyperoxia decreased ventilation in the pregnant women (P less than 0.01) to levels similar to those measured when nonpregnant. The increased ventilation of pregnancy raised arterial O2 saturation (SaO2) from 83 +/- 1 to 87 +/- 0%, and SaO2 was correlated positively with HVR in the pregnant women. The rise in SaO2 compensated for a 0.9 g/100 ml decrease in hemoglobin concentration to preserve arterial O2 content at levels present when nonpregnant. Cardiac output in the 36th wk of pregnancy did not differ significantly from values measured postpartum. The increase in HVR correlated positively with infant birth weight. An increase in HVR may be an important contributor to increased maternal ventilation with pregnancy and infant birth weight at high altitude.

  14. Relationship between double product break point, lactate threshold, and ventilatory threshold in cardiac patients.

    Science.gov (United States)

    Omiya, Kazuto; Itoh, Haruki; Harada, Naomi; Maeda, Tomoko; Tajima, Akihiko; Oikawa, Keiko; Koike, Akira; Aizawa, Tadanori; Fu, Long-Tai; Osada, Naohiko

    2004-03-01

    A double product break point (DPBP) occurs simultaneously with both ventilatory threshold (VT) and lactate threshold (LT) in normal subjects. We sought to determine whether a DPBP also occurs in cardiac patients and to investigate correlations between DPBP, VT and LT (study 1). We also evaluated a non-invasive DPBP measurement system that determined blood pressure automatically by the cuff method (study 2). Study 1 comprised 15 patients [8 men and 7 women, mean (SD) age 47.7 (11.1) years] who performed cardiopulmonary exercise tests on a cycle ergometer. The double product was defined as the product of heart rate and direct systolic blood pressure. Arterial blood samples were obtained for measurement of lactate, pyruvate, pH, and norepinephrine levels. VT was determined by gas analysis, and LT was determined as the lactate/pyruvate ratio. DPBPs were detected in all 15 patients. Double product slopes above the DPBP were significantly greater than those below the DPBP (286.2 vs 98.5/W, P<0.001). The lactate/pyruvate ratio increased, arterial pH decreased, and plasma norepinephrine concentration increased above the DPBP. DPBP had strong positive correlations with VT ( r=0.93) and LT ( r=0.95). Study 2 comprised 65 cardiac patients. The DPBP was detected in 89.2% of patients and correlated closely with VT. We conclude that DPBP occurs near VT and LT in cardiac patients during incremental exercise, that the noninvasive DPBP measurement method is comparable to the invasive method, and that DPBP may be as useful an index of exercise intensity in patients with cardiac disease as VT or LT.

  15. The Effects of a Duathlon Simulation on Ventilatory Threshold and Running Economy

    Directory of Open Access Journals (Sweden)

    Nathaniel T. Berry, Laurie Wideman, Edgar W. Shields, Claudio L. Battaglini

    2016-06-01

    Full Text Available Multisport events continue to grow in popularity among recreational, amateur, and professional athletes around the world. This study aimed to determine the compounding effects of the initial run and cycling legs of an International Triathlon Union (ITU Duathlon simulation on maximal oxygen uptake (VO2max, ventilatory threshold (VT and running economy (RE within a thermoneutral, laboratory controlled setting. Seven highly trained multisport athletes completed three trials; Trial-1 consisted of a speed only VO2max treadmill protocol (SOVO2max to determine VO2max, VT, and RE during a single-bout run; Trial-2 consisted of a 10 km run at 98% of VT followed by an incremental VO2max test on the cycle ergometer; Trial-3 consisted of a 10 km run and 30 km cycling bout at 98% of VT followed by a speed only treadmill test to determine the compounding effects of the initial legs of a duathlon on VO2max, VT, and RE. A repeated measures ANOVA was performed to determine differences between variables across trials. No difference in VO2max, VT (%VO2max, maximal HR, or maximal RPE was observed across trials. Oxygen consumption at VT was significantly lower during Trial-3 compared to Trial-1 (p = 0.01. This decrease was coupled with a significant reduction in running speed at VT (p = 0.015. A significant interaction between trial and running speed indicate that RE was significantly altered during Trial-3 compared to Trial-1 (p < 0.001. The first two legs of a laboratory based duathlon simulation negatively impact VT and RE. Our findings may provide a useful method to evaluate multisport athletes since a single-bout incremental treadmill test fails to reveal important alterations in physiological thresholds.

  16. Partial ventilatory support modalities in acute lung injury and acute respiratory distress syndrome-a systematic review.

    Directory of Open Access Journals (Sweden)

    Sarah M McMullen

    Full Text Available PURPOSE: The efficacy of partial ventilatory support modes that allow spontaneous breathing in patients with acute lung injury (ALI and acute respiratory distress syndrome (ARDS is unclear. The objective of this scoping review was to assess the effects of partial ventilatory support on mortality, duration of mechanical ventilation, and both hospital and intensive care unit (ICU lengths of stay (LOS for patients with ALI and ARDS; the secondary objective was to describe physiologic effects on hemodynamics, respiratory system and other organ function. METHODS: MEDLINE (1966-2009, Cochrane, and EmBase (1980-2009 databases were searched using common ventilator modes as keywords and reference lists from retrieved manuscripts hand searched for additional studies. Two researchers independently reviewed and graded the studies using a modified Oxford Centre for Evidence-Based Medicine grading system. Studies in adult ALI/ARDS patients were included for primary objectives and pre-clinical studies for supporting evidence. RESULTS: Two randomized controlled trials (RCTs were identified, in addition to six prospective cohort studies, one retrospective cohort study, one case control study, 41 clinical physiologic studies and 28 pre-clinical studies. No study was powered to assess mortality, one RCT showed shorter ICU length of stay, and the other demonstrated more ventilator free days. Beneficial effects of preserved spontaneous breathing were mainly physiological effects demonstrated as improvement of gas exchange, hemodynamics and non-pulmonary organ perfusion and function. CONCLUSIONS: The use of partial ventilatory support modalities is often feasible in patients with ALI/ARDS, and may be associated with short-term physiological benefits without appreciable impact on clinically important outcomes.

  17. Hemodynamic and ventilatory response to different levels of hypoxia and hypercapnia in carotid body-denervated rats

    Directory of Open Access Journals (Sweden)

    João Paulo J. Sabino

    2013-01-01

    Full Text Available OBJECTIVE: Chemoreceptors play an important role in the autonomic modulation of circulatory and ventilatory responses to changes in arterial O2 and/or CO2. However, studies evaluating hemodynamic responses to hypoxia and hypercapnia in rats have shown inconsistent results. Our aim was to evaluate hemodynamic and respiratory responses to different levels of hypoxia and hypercapnia in conscious intact or carotid body-denervated rats. METHODS: Male Wistar rats were submitted to bilateral ligature of carotid body arteries (or sham-operation and received catheters into the left femoral artery and vein. After two days, each animal was placed into a plethysmographic chamber and, after baseline measurements of respiratory parameters and arterial pressure, each animal was subjected to three levels of hypoxia (15, 10 and 6% O2 and hypercapnia (10% CO2. RESULTS: The results indicated that 15% O2 decreased the mean arterial pressure and increased the heart rate (HR in both intact (n = 8 and carotid body-denervated (n = 7 rats. In contrast, 10% O2did not change the mean arterial pressure but still increased the HR in intact rats, and it decreased the mean arterial pressure and increased the heart rate in carotid body-denervated rats. Furthermore, 6% O2 increased the mean arterial pressure and decreased the HR in intact rats, but it decreased the mean arterial pressure and did not change the HR in carotid body-denervated rats. The 3 levels of hypoxia increased pulmonary ventilation in both groups, with attenuated responses in carotid body-denervated rats. Hypercapnia with 10% CO2 increased the mean arterial pressure and decreased HR similarly in both groups. Hypercapnia also increased pulmonary ventilation in both groups to the same extent. CONCLUSION: This study demonstrates that the hemodynamic and ventilatory responses varied according to the level of hypoxia. Nevertheless, the hemodynamic and ventilatory responses to hypercapnia did not depend on the

  18. Benchmarking judgmentally adjusted forecasts

    NARCIS (Netherlands)

    Ph.H.B.F. Franses (Philip Hans); L.P. de Bruijn (Bert)

    2015-01-01

    markdownabstractMany publicly available macroeconomic forecasts are judgmentally-adjusted model-based forecasts. In practice usually only a single final forecast is available, and not the underlying econometric model, nor are the size and reason for adjustment known. Hence, the relative weights give

  19. ADJUSTABLE CHIP HOLDER

    DEFF Research Database (Denmark)

    2009-01-01

    An adjustable microchip holder for holding a microchip is provided having a plurality of displaceable interconnection pads for connecting the connection holes of a microchip with one or more external devices or equipment. The adjustable microchip holder can fit different sizes of microchips...

  20. 44 CFR 206.47 - Cost-share adjustments.

    Science.gov (United States)

    2010-10-01

    ... 44 Emergency Management and Assistance 1 2010-10-01 2010-10-01 false Cost-share adjustments. 206.47 Section 206.47 Emergency Management and Assistance FEDERAL EMERGENCY MANAGEMENT AGENCY, DEPARTMENT... Consumers published annually by the Department of Labor. (c) When we determine whether to recommend a...

  1. New modes of assisted mechanical ventilation.

    Science.gov (United States)

    Suarez-Sipmann, F

    2014-05-01

    Recent major advances in mechanical ventilation have resulted in new exciting modes of assisted ventilation. Compared to traditional ventilation modes such as assisted-controlled ventilation or pressure support ventilation, these new modes offer a number of physiological advantages derived from the improved patient control over the ventilator. By implementing advanced closed-loop control systems and using information on lung mechanics, respiratory muscle function and respiratory drive, these modes are specifically designed to improve patient-ventilator synchrony and reduce the work of breathing. Depending on their specific operational characteristics, these modes can assist spontaneous breathing efforts synchronically in time and magnitude, adapt to changing patient demands, implement automated weaning protocols, and introduce a more physiological variability in the breathing pattern. Clinicians have now the possibility to individualize and optimize ventilatory assistance during the complex transition from fully controlled to spontaneous assisted ventilation. The growing evidence of the physiological and clinical benefits of these new modes is favoring their progressive introduction into clinical practice. Future clinical trials should improve our understanding of these modes and help determine whether the claimed benefits result in better outcomes.

  2. Chest radiographs fail to detect right ventricular enlargement and right atrial enlargement in patients with a pure restrictive ventilatory impairment.

    Science.gov (United States)

    Shivkumar, K; Ravi, K; Henry, J W; Eichenhorn, M S; Stein, P D

    1994-08-01

    The validity of measurements of the cardiac silhouette on chest radiographs for the evaluation of right ventricular enlargement and right atrial enlargement in patients with a pure restrictive ventilatory impairment was investigated in 19 patients. The forced vital capacity (FVC) percent predicted in these patients was 59 +/- 12 percent (mean +/- SD) (range, 29 to 79 percent). Right ventricular enlargement, by two-dimensional echocardiography, was defined as a right ventricular area > 20.4 cm2 and right atrial enlargement was defined as a right atrial area > 15.3 cm2. Chest radiographic measurements in the posteroanterior (PA) projection included distance from the midline to the farthest point of the right border of the cardiac silhouette, transverse cardiac diameter, and cardiothoracic ratio. Measurements in the lateral projection included the lateral horizontal transverse diameter, ventral portion of the lateral broad diameter, and obliteration of the retrosternal space. Neither the right ventricular area nor the right atrial area correlated with any of these radiographic measurements. There were no differences in these chest radiographic measurements among patients with normal right ventricular and right atrial dimensions, patients with right ventricular enlargement, and patients with right atrial enlargement. We conclude, therefore, that PA and lateral chest radiographs do not reliably detect right ventricular enlargement or right atrial enlargement in patients with a pure restrictive ventilatory impairment.

  3. Effect of jute dust exposure on ventilatory function and the pertinence of cough and smoking to the response.

    Science.gov (United States)

    Chattopadhyay, B P; Alams, J; Gangopadhyay, P K; Saiyed, H N

    1995-06-01

    The ventilatory capacity of 32 men exposed to jute dust in the jute industry, was estimated at the beginning and end of shifts on the first day and last day of a working week. A detailed occupational, clinical and smoking history was recorded and a more detailed questionnaire on respiratory symptoms was completed prior to the pulmonary function tests. The presence of a productive cough among workers was noted. A mean decrease of forced expiratory volume at one second (FEV1) was observed among workers according to processes, concentration of dust exposure and smoking habit on the first day and last day of the week. The mean difference of values was observed in most of the comparisons but only a few were statistically significant. Low mean values of FEV1 were observed in workers having high dust exposure, a smoking history and productive cough in comparison to the low dust exposure group, non-smokers and workers without cough symptoms. The significant deterioration of FEV1 was found between before shift and after shift values of the low dust exposed group of workers who had a cough and smoking history. The relevance of these factors on the ventilatory function is observed and discussed.

  4. Neonatal stress affects the aging trajectory of female rats on the endocrine, temperature, and ventilatory responses to hypoxia.

    Science.gov (United States)

    Fournier, Sébastien; Gulemetova, Roumiana; Baldy, Cécile; Joseph, Vincent; Kinkead, Richard

    2015-04-01

    Human and animal studies on sleep-disordered breathing and respiratory regulation show that the effects of sex hormones are heterogeneous. Because neonatal stress results in sex-specific disruption of the respiratory control in adult rats, we postulate that it might affect respiratory control modulation induced by ovarian steroids in female rats. The hypoxic ventilatory response (HVR) of adult female rats exposed to neonatal maternal separation (NMS) is ∼30% smaller than controls (24), but consequences of NMS on respiratory control in aging female rats are unknown. To address this issue, whole body plethysmography was used to evaluate the impact of NMS on the HVR (12% O2, 20 min) of middle-aged (MA; ∼57 wk old) female rats. Pups subjected to NMS were placed in an incubator 3 h/day for 10 consecutive days (P3 to P12). Controls were undisturbed. To determine whether the effects were related to sexual hormone decline or aging per se, experiments were repeated on bilaterally ovariectomized (OVX) young (∼12 wk old) adult female rats. OVX and MA both reduced the HVR significantly in control rats but had little effect on the HVR of NMS females. OVX (but not aging) reduced the anapyrexic response in both control and NMS animals. These results show that hormonal decline decreases the HVR of control animals, while leaving that of NMS female animals unaffected. This suggests that neonatal stress alters the interaction between sex hormone regulation and the development of body temperature, hormonal, and ventilatory responses to hypoxia.

  5. Surgical Assisting

    Science.gov (United States)

    ... Insert and remove Foley urinary bladder catheter Place pneumatic tourniquet Confirm procedure with surgeon Drape patient within ... Technology and Surgical Assisting (NBSTSA) offers the CertifiedSurgical First Assistant (CSFA) credential, and the National Surgical Assistant ...

  6. Family Adjustment to Aphasia

    Science.gov (United States)

    ... Public / Speech, Language and Swallowing / Disorders and Diseases Family Adjustment to Aphasia Richard S. was a senior manager ... It also presents a great challenge to the family. There may be tension among family members and ...

  7. Remotely Adjustable Hydraulic Pump

    Science.gov (United States)

    Kouns, H. H.; Gardner, L. D.

    1987-01-01

    Outlet pressure adjusted to match varying loads. Electrohydraulic servo has positioned sleeve in leftmost position, adjusting outlet pressure to maximum value. Sleeve in equilibrium position, with control land covering control port. For lowest pressure setting, sleeve shifted toward right by increased pressure on sleeve shoulder from servovalve. Pump used in aircraft and robots, where hydraulic actuators repeatedly turned on and off, changing pump load frequently and over wide range.

  8. Weighted triangulation adjustment

    Science.gov (United States)

    Anderson, Walter L.

    1969-01-01

    The variation of coordinates method is employed to perform a weighted least squares adjustment of horizontal survey networks. Geodetic coordinates are required for each fixed and adjustable station. A preliminary inverse geodetic position computation is made for each observed line. Weights associated with each observed equation for direction, azimuth, and distance are applied in the formation of the normal equations in-the least squares adjustment. The number of normal equations that may be solved is twice the number of new stations and less than 150. When the normal equations are solved, shifts are produced at adjustable stations. Previously computed correction factors are applied to the shifts and a most probable geodetic position is found for each adjustable station. Pinal azimuths and distances are computed. These may be written onto magnetic tape for subsequent computation of state plane or grid coordinates. Input consists of punch cards containing project identification, program options, and position and observation information. Results listed include preliminary and final positions, residuals, observation equations, solution of the normal equations showing magnitudes of shifts, and a plot of each adjusted and fixed station. During processing, data sets containing irrecoverable errors are rejected and the type of error is listed. The computer resumes processing of additional data sets.. Other conditions cause warning-errors to be issued, and processing continues with the current data set.

  9. Heart rate response during a simulated Olympic boxing match is predominantly above ventilatory threshold 2: a cross sectional study

    Directory of Open Access Journals (Sweden)

    de Lira CA

    2013-07-01

    Full Text Available Claudio Andre Barbosa de Lira,1 Luiz Fernando Peixinho-Pena,2 Rodrigo Luiz Vancini1,2 Rafael Júlio de Freitas Guina Fachina,3,4 Alexandre Aparecido de Almeida,2 Marília dos Santos Andrade,2 Antonio Carlos da Silva2 1Setor de Fisiologia Humana e do Exercício, Universidade Federal de Goiás (UFG, Câmpus Jataí, Jataí, GO, Brazil; 2Departamento de Fisiologia, Universidade Federal de São Paulo (UNIFESP, São Paulo, SP, Brazil; 3Departamento de Ciência do Esporte, Faculdade de Educação Física (FEF, Universidade Estadual de Campinas (UNICAMP, Campinas, Brazil; 4Confederação Brasileira de Basketball (CBB, Rio de Janeiro, Brazil Abstract: The present study aimed to describe heart rate (HR responses during a simulated Olympic boxing match and examine physiological parameters of boxing athletes. Ten highly trained Olympic boxing athletes (six men and four women performed a maximal graded exercise test on a motorized treadmill to determine maximal oxygen uptake (52.2 mL · kg-1 · min-1 ± 7.2 mL · kg-1 · min-1 and ventilatory thresholds 1 and 2. Ventilatory thresholds 1 and 2 were used to classify the intensity of exercise based on respective HR during a boxing match. In addition, oxygen uptake (VO2 was estimated during the match based on the HR response and the HR-VO2 relationship obtained from a maximal graded exercise test for each participant. On a separate day, participants performed a boxing match lasting three rounds, 2 minutes each, with a 1-minute recovery period between each round, during which HR was measured. In this context, HR and VO2 were above ventilatory threshold 2 during 219.8 seconds ± 67.4 seconds. There was an increase in HR and VO2 as a function of round (round 3 < round 2 < round 1, P < 0.0001.These findings may direct individual training programs for boxing practitioners and other athletes. Keywords: heart rate, physiological profile, intermittent exercise, combat sports, boxing

  10. Oxygenation Threshold Derived from Near-Infrared Spectroscopy: Reliability and Its Relationship with the First Ventilatory Threshold

    Science.gov (United States)

    Jaspers, Richard T.; Blokland, Ilse J.; Achterberg, Chantal; Visser, Jurrian M.; den Uil, Anne R.; Hofmijster, Mathijs J.; Levels, Koen; Noordhof, Dionne A.; de Haan, Arnold; de Koning, Jos J.; van der Laarse, Willem J.; de Ruiter, Cornelis J.

    2016-01-01

    Background Near-infrared spectroscopy (NIRS) measurements of oxygenation reflect O2 delivery and utilization in exercising muscle and may improve detection of a critical exercise threshold. Purpose First, to detect an oxygenation breakpoint (Δ[O2HbMb-HHbMb]-BP) and compare this breakpoint to ventilatory thresholds during a maximal incremental test across sexes and training status. Second, to assess reproducibility of NIRS signals and exercise thresholds and investigate confounding effects of adipose tissue thickness on NIRS measurements. Methods Forty subjects (10 trained male cyclists, 10 trained female cyclists, 11 endurance trained males and 9 recreationally trained males) performed maximal incremental cycling exercise to determine Δ[O2HbMb-HHbMb]-BP and ventilatory thresholds (VT1 and VT2). Muscle haemoglobin and myoglobin O2 oxygenation ([HHbMb], [O2HbMb], SmO2) was determined in m. vastus lateralis. Δ[O2HbMb-HHbMb]-BP was determined by double linear regression. Trained cyclists performed the maximal incremental test twice to assess reproducibility. Adipose tissue thickness (ATT) was determined by skinfold measurements. Results Δ[O2HbMb-HHbMb]-BP was not different from VT1, but only moderately related (r = 0.58–0.63, p<0.001). VT1 was different across sexes and training status, whereas Δ[O2HbMb-HHbMb]-BP differed only across sexes. Reproducibility was high for SmO2 (ICC = 0.69–0.97), Δ[O2HbMb-HHbMb]-BP (ICC = 0.80–0.88) and ventilatory thresholds (ICC = 0.96–0.99). SmO2 at peak exercise and at occlusion were strongly related to adipose tissue thickness (r2 = 0.81, p<0.001; r2 = 0.79, p<0.001). Moreover, ATT was related to asymmetric changes in Δ[HHbMb] and Δ[O2HbMb] during incremental exercise (r = -0.64, p<0.001) and during occlusion (r = -0.50, p<0.05). Conclusion Although the oxygenation threshold is reproducible and potentially a suitable exercise threshold, VT1 discriminates better across sexes and training status during maximal stepwise

  11. Comparison of heart rate deflection and ventilatory threshold during a field cross-country roller-skiing test.

    Science.gov (United States)

    Fabre, Nicolas; Passelergue, Philippe; Bouvard, Marc; Perrey, Stéphane

    2008-11-01

    This study was to assess whether the point of deflection from linearity of heart rate (HRd) could be an accurate predictor of ventilatory threshold (VT2) during a specific cross-country roller-skiing (RS) test. Ten well-trained cross-country skiers performed a maximal and incremental RS test in the field and a standardized maximal and incremental treadmill running (TR) test in the laboratory. Values of oxygen uptake (VO2) and heart rate (HR) were continuously recorded during all exercises by a portable breath-by-breath gas exchange measurement system and a wireless Polar monitoring system, respectively. The VT2 and HRd points were individually determined by visual analysis during RS. Maximal VO2 (VO2 max) and HR were higher (p cross-country coaches and skiers to evaluate and control specific aerobic training loads.

  12. Association of toxic and essential metals with atopy markers and ventilatory lung function in women and men

    Energy Technology Data Exchange (ETDEWEB)

    Pizent, Alica [Institute for Medical Research and Occupational Health, Zagreb (Croatia)], E-mail: apizent@imi.hr; Macan, Jelena; Jurasovic, Jasna; Varnai, Veda Marija; Milkovic-Kraus, Sanja; Kanceljak-Macan, Bozica [Institute for Medical Research and Occupational Health, Zagreb (Croatia)

    2008-02-15

    The association of age, smoking, alcohol, superoxide dismutase (SOD), glutathione peroxidase (GPx), blood lead (BPb) and cadmium (BCd) levels, and serum levels of copper (SCu), zinc (SZn) and selenium (SSe) with atopic status and ventilatory function was examined in the groups of 166 women and 50 men with no occupational exposure to metals or other xenobiotics. Markers of atopy included serum total IgE, skin prick test (SPT) to common inhalatory allergens, non-specific nasal reactivity (NNR) and non-specific bronchial reactivity (NBR). Parameters of ventilatory function included forced vital capacity (FVC) and forced expiratory volume in the first second (FEV{sub 1}). Significantly higher BPb, SZn, IgE and prevalence of positive SPT, and lower SCu and NNR was found in men than in women. Fifteen women taking female sex hormones (HT) had significantly higher SCu than women without HT. Regression models showed significant inverse associations between IgE and SCu (P = 0.021) and NNR and SCu (P = 0.044) in women. When excluding women with HT, the association of SCu and total IgE became of borderline significance (P = 0.051), association between SCu and NNR disappeared, and significant positive association between total IgE and BPb emerged (P = 0.046). In men, significant inverse association was found between positive SPT and SSe, and between NBR and SSe. A decrease in FVC% and FEV{sub 1}% was associated with an increase in smoking intensity (P < 0.001) and a decrease in SZn (P = 0.043 and P = 0.053, respectively). These results were observed at the levels of the metals comparable to those in general populations worldwide. The observed differences between men and women may partly be explained by different levels of relevant toxic and essential metals, and their combination. The role of female HT in associations of atopy markers and SCu should be further investigated.

  13. Association of ADAM33 gene polymorphism and arginase activity with susceptibility to ventilatory impairment in wood dust-exposed workers.

    Science.gov (United States)

    Saad-Hussein, A; Thabet, E H; Taha, M M; Shahy, E M; Mahdy-Abdallah, H

    2016-09-01

    ADAM33 represents an important gene of susceptibility for lung function impairment. This work aimed to evaluate the association between genetic polymorphism of ADAM33 at four single nucleotide polymorphisms (T1, T2, S1, and Q1) and arginase activity with respiratory functions impairment in wood workers. The study was done to compare ventilatory functions and arginase activity of 82 wood workers and 81 controls. Genotyping was determined by using the polymerase chain restriction fragment length polymorphism method. Forced expiratory volume in the first second (FEV1), forced vital capacity (FVC), and peak expiratory flow rate (PEF) of the workers were significantly reduced compared with the controls. T1 single nucleotide polymorphism (SNP) was associated with obvious decline in the FEV1, FVC, and PEF in wood workers, while T2 SNP was associated with decline in FEV1 and PEF. A significant increase in arginase activity was found in T2 and S1 SNPs of the exposed workers. Increase in duration of exposure was correlated with the decline in ventilatory functions. This inverse correlation was significant for pulmonary function indices in AA and GG genotypes of T1 and T2, respectively. Moreover, significance was detected for FVC and FEV1 in AA and GA genotypes of S1 and Q1. A positive correlation between arginase activity and duration of exposure was found to be significant in GG genotype of S1 SNP. An association between ADAM33 gene polymorphism and impaired lung functions was detected in wood dust-exposed workers. Arginase activity may play an associated important role in increasing this impairment in wood workers.

  14. Drenagem venosa assistida através da utilização controlada de vácuo no reservatório venoso do oxigenador Assisted venous drainage using an adjustable vacuum system: a clinical study

    Directory of Open Access Journals (Sweden)

    Luiz Fernando CANÊO

    1999-04-01

    Full Text Available Nas operações minimamente invasivas o uso de cânula de menor calibre facilita a realização dos procedimentos cirúrgicos, mas, por outro lado, a drenagem venosa pode ser prejudicada. O emprego de vácuo no reservatório venoso do oxigenador é uma maneira simples e de baixo custo na correção do problema. O objetivo deste trabalho é apresentar nossa experiência com um dispositivo que permite além da utilização do vácuo, a sua regulagem conforme a necessidade específica do paciente e cânula empregada. Esse dispositivo consiste de uma válvula reguladora de vácuo, um filtro para a retenção de líquidos do ar aspirado e um manômetro eletrônico de pressão negativa. Os testes de bancada evidenciaram eficiência e segurança na aplicação da pressão negativa no oxigenador até 250 mmHg em temperaturas de até 40oC. O estudo clínico consistiu, inicialmente, na aplicação em 11 pacientes com esternotomia total. Posteriormente, foi utilizado em esternotomias parciais para tratamento da doença isolada da valva aórtica em 5 casos (L invertido e 4 casos de atriosseptoplastia. Esse dispositivo permitiu a utilização de cânulas de diâmetros menores que as cânulas únicas convencionais, variando de 32 a 26 Fr, com a utilização de pressões negativas de 62,40 ± 11,69 mmHg com drenagem venosa satisfatória, sem evidências indiretas de hemólise. O dispositivo por nós idealizado permitiu a drenagem venosa assistida com a utilização de vácuo de forma controlada, segura e eficiente.The use of small cannulae improves surgical field visualization in minimally invasive cardiac surgery, but may compromise the venous drainage. Vacuum assisted venous drainage is a simple and nonexpensive solution to this problem. We report our clinical experience using a device consisting of a negative pressure regulator, a vacuum line filter and an electronic manometer. The safety and efficacy of this CPB system was first tested in vitro, applying a

  15. Auto Adjusting Astronomical Telescope

    Directory of Open Access Journals (Sweden)

    Rohit R. Ghalsasi

    2014-04-01

    Full Text Available Astronomical telescope is powerful and basic tool for star or celestial observation. Here we proposed integrated system using Raspberry Pi for auto adjusting astronomical telescope. This integrated circuit helps to control stellar monitoring, stellar targeting, and tracking functions of telescope. Astro compass gives the direction of the celestial objects.

  16. Psychological Adjustment and Homosexuality.

    Science.gov (United States)

    Gonsiorek, John C.

    In this paper, the diverse literature bearing on the topic of homosexuality and psychological adjustment is critically reviewed and synthesized. The first chapter discusses the most crucial methodological issue in this area, the problem of sampling. The kinds of samples used to date are critically examined, and some suggestions for improved…

  17. Sustainable urban regime adjustments

    DEFF Research Database (Denmark)

    Quitzau, Maj-Britt; Jensen, Jens Stissing; Elle, Morten;

    2013-01-01

    The endogenous agency that urban governments increasingly portray by making conscious and planned efforts to adjust the regimes they operate within is currently not well captured in transition studies. There is a need to acknowledge the ambiguity of regime enactment at the urban scale. This direc...

  18. Assistive Technology

    Science.gov (United States)

    ... Page Resize Text Printer Friendly Online Chat Assistive Technology Assistive technology (AT) is any service or tool that helps ... be difficult or impossible. For older adults, such technology may be a walker to improve mobility or ...

  19. Anesthetic management of robot-assisted thoracoscopic thymectomy

    Directory of Open Access Journals (Sweden)

    Anil Karlekar

    2016-01-01

    Full Text Available Myasthenia gravis (MG is a rare disorder involving neuromuscular junction. In conjunction with medical therapy, thymectomy is a known modality of treatment of MG and has shown to increase the probability of remission and overall symptomatic improvement. For minimally invasive thymectomy, video-.assisted thoracoscopic surgery has been the preferred surgical approach till recently. The robotic surgical procedure must necessarily bring new challenges to the anesthesiologists to effectively meet the specific requirements of the technique. At present, there is a paucity of literature regarding the anesthetic concerns of robotic assisted thymectomy, patient in question specifically posed a challenge since different maneuvers and techniques had to be tried to obtain optimum surgical conditions with stable ventilatory and hemodynamic parameters. Concerns of patient positioning and hemodynamic monitoring have also been discussed.

  20. Assistive Technologies

    Science.gov (United States)

    Auat Cheein, Fernando A., Ed.

    2012-01-01

    This book offers the reader new achievements within the Assistive Technology field made by worldwide experts, covering aspects such as assistive technology focused on teaching and education, mobility, communication and social interactivity, among others. Each chapter included in this book covers one particular aspect of Assistive Technology that…

  1. 13 CFR 107.1540 - Distributions by Licensee-Prioritized Payments and Adjustments.

    Science.gov (United States)

    2010-01-01

    ... 13 Business Credit and Assistance 1 2010-01-01 2010-01-01 false Distributions by Licensee-Prioritized Payments and Adjustments. 107.1540 Section 107.1540 Business Credit and Assistance SMALL BUSINESS ADMINISTRATION SMALL BUSINESS INVESTMENT COMPANIES SBA Financial Assistance for Licensees...

  2. Metric adjusted skew information

    DEFF Research Database (Denmark)

    Hansen, Frank

    2008-01-01

    establish a connection between the geometrical formulation of quantum statistics as proposed by Chentsov and Morozova and measures of quantum information as introduced by Wigner and Yanase and extended in this article. We show that the set of normalized Morozova-Chentsov functions describing the possible...... quantum statistics is a Bauer simplex and determine its extreme points. We determine a particularly simple skew information, the "¿-skew information," parametrized by a ¿ ¿ (0, 1], and show that the convex cone this family generates coincides with the set of all metric adjusted skew informations.......We extend the concept of Wigner-Yanase-Dyson skew information to something we call "metric adjusted skew information" (of a state with respect to a conserved observable). This "skew information" is intended to be a non-negative quantity bounded by the variance (of an observable in a state...

  3. Ventricular assist device

    Science.gov (United States)

    VAD; RVAD; LVAD; BVAD; Right ventricular assist device; Left ventricular assist device; Biventricular assist device; Heart pump; Left ventricular assist system; LVAS; Implantable ventricular assist device

  4. Fiscal adjustment in Brazil

    Directory of Open Access Journals (Sweden)

    Fabiana Rocha

    2003-03-01

    Full Text Available Two questions are addressed in this paper. The first one is the determination of periods of fiscal consolidation and fiscal stimulus. The second one is the importance of the composition of fiscal adjustments for their success, defined as a declining debt to GDP ratio. We, characterize 1994 and 1999 as points of fiscal consolidation. The 1994 consolidation can not be considered successful since after that period the debt to GDP ratio has grown continuously. The adjustment can be characterized as a type 2 adjustment (Alesina and Perotti (1997 in the sense that cuts were made mainly in public investment, while government wages and transfers remained almost unchanged. This type of adjustment usually has a low likelihood of being a success.Duas questões são tratadas neste artigo. A primeira é a determinação dos períodos de consolidação fiscal e estímulo fiscal. A segunda questão é a importância da composição dos ajustamentos fiscais para o seu sucesso, definido como um declínio na razo dívida/PIB. Nós, caracterizamos 1994 e 1999 como pontos de consolidação fiscal. A consolidação de 1994 não pode ser considerada um sucesso pois nos anos seguintes a razão dívida/PIB cresceu continuamente. O ajustamento pode ser considerado como um ajustamento do tipo 2 (Alesina and Perotti, 1997 no sentido de que foram feitos cortes principalmente no investimento público, enquanto os salários e transferências permaneceram praticamente inalterados. Este tipo de ajustamento geralmente tem uma baixa probabilidade de sucesso.

  5. Adjustment Criterion and Algorithm in Adjustment Model with Uncertain

    Directory of Open Access Journals (Sweden)

    SONG Yingchun

    2015-02-01

    Full Text Available Uncertainty often exists in the process of obtaining measurement data, which affects the reliability of parameter estimation. This paper establishes a new adjustment model in which uncertainty is incorporated into the function model as a parameter. A new adjustment criterion and its iterative algorithm are given based on uncertainty propagation law in the residual error, in which the maximum possible uncertainty is minimized. This paper also analyzes, with examples, the different adjustment criteria and features of optimal solutions about the least-squares adjustment, the uncertainty adjustment and total least-squares adjustment. Existing error theory is extended with new observational data processing method about uncertainty.

  6. Relationships (II) of International Classification of High-resolution Computed Tomography for Occupational and Environmental Respiratory Diseases with ventilatory functions indices for parenchymal abnormalities.

    Science.gov (United States)

    Tamura, Taro; Suganuma, Narufumi; Hering, Kurt G; Vehmas, Tapio; Itoh, Harumi; Akira, Masanori; Takashima, Yoshihiro; Hirano, Harukazu; Kusaka, Yukinori

    2015-01-01

    The International Classification of High-Resolution Computed Tomography (HRCT) for Occupational and Environmental Respiratory Diseases (ICOERD) is used to screen and diagnose respiratory illnesses. Using univariate and multivariate analysis, we investigated the relationship between subject characteristics and parenchymal abnormalities according to ICOERD, and the results of ventilatory function tests (VFT). Thirty-five patients with and 27 controls without mineral-dust exposure underwent VFT and HRCT. We recorded all subjects' occupational history for mineral dust exposure and smoking history. Experts independently assessed HRCT using the ICOERD parenchymal abnormalities (Items) grades for well-defined rounded opacities (RO), linear and/or irregular opacities (IR), and emphysema (EM). High-resolution computed tomography showed that 11 patients had RO; 15 patients, IR; and 19 patients, EM. According to the multiple regression model, age and height had significant associations with many indices ventilatory functions such as vital capacity, forced vital capacity, and forced expiratory volume in 1 s (FEV1). The EM summed grades on the upper, middle, and lower zones of the right and left lungs also had significant associations with FEV1 and the maximum mid-expiratory flow rate. The results suggest the ICOERD notation is adequate based on the good and significant multiple regression modeling of ventilatory function with the EM summed grades.

  7. Jordan Adjusted Human Development

    OpenAIRE

    Ababsa, Myriam

    2014-01-01

    Jordan Human Development Index (HDI) and Adjusted Human Development Index (IHDI) In 1990, the United Nations Development Programme designed a Human Development Index composed of life expectancy at birth, level of education and gross domestic product (GDP) per capita. In 2011, the UNDP ranked Jordan 95th out of 187 countries with a human development index of 0.698, up from 0.591 in 1990, making it the leading medium-range country for human development (fig. VIII.1). In 2010, the inequality adj...

  8. Adjustable Reeds For Weaving

    Science.gov (United States)

    Farley, Gary L.

    1994-01-01

    Local characteristics of fabrics varied to suit special applications. Adjustable reed machinery proposed for use in weaving fabrics in various net shapes, widths, yarn spacings, and yarn angles. Locations of edges of fabric and configuration of warp and filling yarns varied along fabric to obtain specified properties. In machinery, reed wires mounted in groups on sliders, mounted on lengthwise rails in reed frame. Mechanisms incorporated to move sliders lengthwise, parallel to warp yarns, by sliding them along rails; move sliders crosswise by translating reed frame rails perpendicular to warp yarns; and crosswise by spreading reed rails within group. Profile of reed wires in group on each slider changed.

  9. 75 FR 62759 - Trade Adjustment Assistance for Farmers

    Science.gov (United States)

    2010-10-13

    ... data for the most recent, full marketing year or full official marketing season, a greater than 15... marketing period, contributed importantly to the decrease in one of the above factors for the agricultural..., Farm Service Agency, Agricultural Marketing Service, and FAS. After a review, the...

  10. 75 FR 9087 - Trade Adjustment Assistance for Farmers

    Science.gov (United States)

    2010-03-01

    ...) Reflect the skills gained by the producer through the courses described in paragraph (c) of this section; and (2) Demonstrate how the producer will apply those skills to the circumstances of the producer. (e... certification from a certified public accountant or attorney, that relied upon information from a...

  11. 75 FR 42376 - Trade Adjustment Assistance for Farmers

    Science.gov (United States)

    2010-07-21

    ...% Puerto Rico Coffee Export Board, Inc. on behalf of coffee producers in Puerto Rico. The Administrator will determine within 40 days whether increasing imports of coffee contributed importantly to a greater than 15-percent decrease in the average annual price, production quantity, or production value...

  12. Trade Adjustment Assistant: Experiences of Six Trade-Impacted Communities

    Science.gov (United States)

    2001-08-01

    Mexico have contributed to their loss of employment. Once a TAA or NAFTA-TAA petition is approved covered workers must meet several tests regarding...used as a Workforce Development Center and a Business Resource Center. The second loan was made in March 2001, for $180,000 to La Mujer Obrera, an...the former Levi- Strauss plant and a $1.2 million grant to La Mujer Obrera, an advocacy group for dislocated women workers. Watsonville and El Paso

  13. The modified Dmax method is reliable to predict the second ventilatory threshold in elite cross-country skiers.

    Science.gov (United States)

    Fabre, Nicolas; Balestreri, Filippo; Pellegrini, Barbara; Schena, Federico

    2010-06-01

    This study was designed to evaluate, in elite cross-country skiers, the capacity of the DMAX lactate threshold method and its modified version (DMAX MOD) to accurately predict the second ventilatory threshold (VT2). Twenty-three elite cross-country skiers carried out an incremental roller-ski test on a motorized treadmill. Ventilation, heart rate (HR), and gas exchanges were continuously recorded during the test. Blood was sampled at the end of each 3-minute work stage for lactate concentration measurements. The VT2 was individually determined by visual analysis. The DMAX, DMAX MOD points also with the 4 mmol.L(-1) fixed lactate concentration value (4 mM) were determined by a computerized program. Paired t tests showed nonsignificant differences between HR at VT2 and HR at DMAX MOD, between HR at VT2 and HR at 4 mM, and between HR at DMAX MOD and HR at 4 mM. HR at DMAX was significantly lower than HR at VT2, DMAX MOD, and at 4 mM (pcross-country skiers.

  14. Unusual Ventilatory Response to Exercise in Patient with Arnold-Chiari Type 1 Malformation after Posterior Fossa Decompression

    Directory of Open Access Journals (Sweden)

    Keely Smith

    2016-01-01

    Full Text Available We present a case of a 17-year-old Hispanic male with Arnold-Chiari Type 1 [AC-Type 1] with syringomyelia, status post decompression, who complains of exercise intolerance, headaches, and fatigue with exertion. The patient was found to have diurnal hypercapnia and nocturnal alveolar hypoventilation. Cardiopulmonary testing revealed blunting of the ventilatory response to the rise in carbon dioxide (CO2 resulting in failure of the parallel correlation between increased CO2 levels and ventilation; the expected vertical relationship between PETCO2 and minute ventilation during exercise was replaced with an almost horizontal relationship. No new pathology of the brainstem was discovered by MRI or neurological evaluation to explain this phenomenon. The patient was placed on continuous noninvasive open ventilation (NIOV during the day and CPAP at night for a period of 6 months. His pCO2 level decreased to normal limits and his symptoms improved; specifically, he experienced less headaches and fatigue during exercise. In this report, we describe the abnormal response to exercise that patients with AC-Type 1 could potentially experience, even after decompression, characterized by the impairment of ventilator response to hypercapnia during exertion, reflecting a complete loss of chemical influence on breathing with no evidence of abnormality in the corticospinal pathway.

  15. Ventilatory responses to exercise and CO2 after menopause in healthy women: effects of age and fitness.

    Science.gov (United States)

    Davenport, Margie H; Beaudin, Andrew E; Brown, Allison D; Leigh, Richard; Poulin, Marc J

    2012-10-15

    The extent to which aging affects respiratory control in postmenopausal women remains relatively unknown. In a cross-sectional study of 39 postmenopausal women (50-79 years), we examined the influence of age and fitness on the ventilatory responses to hypercapnia (HCVR; +8 mmHg) and exercise (ΔV˙(E)/ΔV˙CO2) above and below the anaerobic threshold (AT). Data were analyzed using the full cohort, by age (younger postmenopausal: YPM, 50-64 years; and older postmenopausal: OPM, 65-79 years) and fitness as per our previous work (Active: V˙O2max ≥90% age-predicted values; and Sedentary: V˙O2max fitness, was inversely related to ΔV˙(E)/ΔV˙CO2 above AT (YPM: 46.8±11.5; OPM: 34.8±6.9, p<0.01) which may be explained, at least in part, by age-related declines in lung function. HCVR and ΔV˙(E)/ΔV˙CO2 were not correlated.

  16. Unusual Ventilatory Response to Exercise in Patient with Arnold-Chiari Type 1 Malformation after Posterior Fossa Decompression

    Science.gov (United States)

    Smith, Keely; Gomez-Rubio, Ana M.; Harris, Tomika S.; Brooks, Lauren E.

    2016-01-01

    We present a case of a 17-year-old Hispanic male with Arnold-Chiari Type 1 [AC-Type 1] with syringomyelia, status post decompression, who complains of exercise intolerance, headaches, and fatigue with exertion. The patient was found to have diurnal hypercapnia and nocturnal alveolar hypoventilation. Cardiopulmonary testing revealed blunting of the ventilatory response to the rise in carbon dioxide (CO2) resulting in failure of the parallel correlation between increased CO2 levels and ventilation; the expected vertical relationship between PETCO2 and minute ventilation during exercise was replaced with an almost horizontal relationship. No new pathology of the brainstem was discovered by MRI or neurological evaluation to explain this phenomenon. The patient was placed on continuous noninvasive open ventilation (NIOV) during the day and CPAP at night for a period of 6 months. His pCO2 level decreased to normal limits and his symptoms improved; specifically, he experienced less headaches and fatigue during exercise. In this report, we describe the abnormal response to exercise that patients with AC-Type 1 could potentially experience, even after decompression, characterized by the impairment of ventilator response to hypercapnia during exertion, reflecting a complete loss of chemical influence on breathing with no evidence of abnormality in the corticospinal pathway. PMID:27418995

  17. Continuously adjustable Pulfrich spectacles

    Science.gov (United States)

    Jacobs, Ken; Karpf, Ron

    2011-03-01

    A number of Pulfrich 3-D movies and TV shows have been produced, but the standard implementation has inherent drawbacks. The movie and TV industries have correctly concluded that the standard Pulfrich 3-D implementation is not a useful 3-D technique. Continuously Adjustable Pulfrich Spectacles (CAPS) is a new implementation of the Pulfrich effect that allows any scene containing movement in a standard 2-D movie, which are most scenes, to be optionally viewed in 3-D using inexpensive viewing specs. Recent scientific results in the fields of human perception, optoelectronics, video compression and video format conversion are translated into a new implementation of Pulfrich 3- D. CAPS uses these results to continuously adjust to the movie so that the viewing spectacles always conform to the optical density that optimizes the Pulfrich stereoscopic illusion. CAPS instantly provides 3-D immersion to any moving scene in any 2-D movie. Without the glasses, the movie will appear as a normal 2-D image. CAPS work on any viewing device, and with any distribution medium. CAPS is appropriate for viewing Internet streamed movies in 3-D.

  18. Ventilatory responses to carbon dioxide at low and high levels of oxygen are elevated after episodic hypoxia in men compared with women.

    Science.gov (United States)

    Morelli, Chris; Badr, M Safwan; Mateika, Jason H

    2004-11-01

    We hypothesized that the acute ventilatory response to carbon dioxide in the presence of low and high levels of oxygen would increase to a greater extent in men compared with women after exposure to episodic hypoxia. Eleven healthy men and women of similar race, age, and body mass index completed a series of rebreathing trials before and after exposure to eight 4-min episodes of hypoxia. During the rebreathing trials, subjects initially hyperventilated to reduce the end-tidal partial pressure of carbon dioxide (PetCO2) below 25 Torr. Subjects then rebreathed from a bag containing a normocapnic (42 Torr), low (50 Torr), or high oxygen gas mixture (150 Torr). During the trials, PetCO2 increased while the selected level of oxygen was maintained. The point at which minute ventilation began to rise in a linear fashion as PetCO2 increased was considered to be the carbon dioxide set point. The ventilatory response below and above this point was determined. The results showed that the ventilatory response to carbon dioxide above the set point was increased in men compared with women before exposure to episodic hypoxia, independent of the oxygen level that was maintained during the rebreathing trials (50 Torr: men, 5.19 +/- 0.82 vs. women, 4.70 +/- 0.77 l x min(-1) x Torr(-1); 150 Torr: men, 4.33 +/- 1.15 vs. women, 3.21 +/- 0.58 l x min(-1) x Torr(-1)). Moreover, relative to baseline measures, the ventilatory response to carbon dioxide in the presence of low and high oxygen levels increased to a greater extent in men compared with women after exposure to episodic hypoxia (50 Torr: men, 9.52 +/- 1.40 vs. women, 5.97 +/- 0.71 l x min(-1) x Torr(-1); 150 Torr: men, 5.73 +/- 0.81 vs. women, 3.83 +/- 0.56 l x min(-1) x Torr(-1)). Thus we conclude that enhancement of the acute ventilatory response to carbon dioxide after episodic hypoxia is sex dependent.

  19. Adolescent Mothers' Adjustment to Parenting.

    Science.gov (United States)

    Samuels, Valerie Jarvis; And Others

    1994-01-01

    Examined adolescent mothers' adjustment to parenting, self-esteem, social support, and perceptions of baby. Subjects (n=52) responded to questionnaires at two time periods approximately six months apart. Mothers with higher self-esteem at Time 1 had better adjustment at Time 2. Adjustment was predicted by Time 2 variables; contact with baby's…

  20. Adjusting to the Emergent

    DEFF Research Database (Denmark)

    Revsbæk, Line

    In her doctoral thesis Line Revsbaek explores newcomer innovation related to organizational entry processes in a changing organization. She introduces process philosophy and complexity theory to research on organizational socialization and newcomer innovation. The study challenges assumptions...... in standardized induction programs where newcomers are cast in roles as insecure novices needing to be “taught the ropes” of the organizational culture. Linked with this, it is suggested that the prevailing dichotomy of ‘newcomer assimilation’ versus ‘organizational accommodation’ is replaced with a notion...... of ‘adjusting to the emergent’. Newcomer innovation is portrayed as carrying a variety of possible significations, such as unintentional innovation effects of newcomer’s proactive self-socializing behavior; an inspirational basis for designing innovation-generating employee induction; ‘resonant instances...

  1. 24 CFR 880.609 - Adjustment of contract rents.

    Science.gov (United States)

    2010-04-01

    ... date of the contract in accordance with 24 CFR part 888. (b) Special additional adjustments. For all... CFR part 883 projects, by the Agency and HUD), to reflect increases in the actual and necessary... for assisted units and comparable unassisted units except to the extent that the differences...

  2. 神经调节辅助通气模式在机械通气患者撤机中的应用%The adhibition of neurally adjusted ventilation assist in emergency intensive care unit patients with the weaning from mechanical ventilation

    Institute of Scientific and Technical Information of China (English)

    王丽娜; 王妮; 王维霞; 邱晓娟; 张琼; 程三放

    2015-01-01

    目的:探讨EIC U机械通气患者应用神经调节辅助通气模式进行撤机的临床效果。方法:将符合撤机标准的62例机械辅助通气患者随机分为NAVA组和PSV 组各31例。NAVA组应用神经调节辅助通气(NAVA)模式进行撤机,PSV组应用压力支持通气(PSV)模式进行撤机。比较两组患者撤机成功率、再插管率及有创通气时间。结果:NAVA组成功撤机28例(90.3%),3例(9.7%)再插管继续有创通气;PS V 组成功撤机21例(67.7%),9例(29%)再插管继续有创通气;NAVA组有创通气时间4.42±1.03d ,PSV 组8.21±2.43d。两组撤机成功率、再插管率及有创通气时间比较差异有统计学意义(P<0.05)。结论:采用神经调节辅助通气模式进行撤机,可以提高撤机成功率,缩短机械通气时间。%Objective:To investigate the application value of the neurally adjusted ventilation assist in e‐mergency intensive care unit patients with the weaning from mechanical ventilation .Methods :62 casess with the mechanical ventilation who up to the standard of ventilator weaning were divided into two groups randomly :31 cases with NAVA (Neurally adjusted ventilation assist ) and the other 31 cases with PSV (Pressure support ventilation) . Then we compared the differences of the success rate of ventilator weaning ,reintubation rate and the invasive venti‐lation time between two groups .Results :Compared to the PSV group ,the NAVA group got higher success rate of ventilator weaning (90 .3% VS 67 .7% ) ,lower reintubation rate (9 .7% VS 29% )and less invasive ventilation time (4 .42 ± 1 .03d VS 8 .21 ± 2 .43d) .Conclusion :We can get higher success rate of ventilator weaning ,lower reintuba‐tion rate and less invasive ventilation time with the NAVA in emergency intensive care unit patients with the weaning from mechanical ventilation .

  3. Efeito da obesidade na função ventilatória Impact of obesity on ventilatory function

    Directory of Open Access Journals (Sweden)

    Perran Boran

    2007-04-01

    Full Text Available OBJETIVO: Embora a obesidade tenha sido associada ao comprometimento grave da ventilação, a maior parte da população estudada constitui-se de adultos com obesidade mórbida. Nosso objetivo foi investigar os efeitos da obesidade leve na função ventilatória de pacientes pediátricos. MÉTODOS: Estudo transversal controlado que analisou 80 pacientes (M/F: 35/45 avaliados em nosso ambulatório, com queixa de sobrepeso, sem histórico de asma ou de outras atopias, comparando-os a um grupo controle com 50 crianças de peso normal controladas para a idade e para o sexo. A média de idade dos pacientes foi de 9,7±2,5 anos (7 a 15 anos. Todos os indivíduos foram submetidos a medições antropométricas e à espirometria. A capacidade vital forçada (CVF e o volume expiratório forçado no primeiro segundo (VEF1 foram usados como medidas da função ventilatória. RESULTADOS: Não houve diferenças significativas nas VEF1%, CVF% e VEF1%/CVF% por grupo de estudo (p > 0,05. Apenas três pacientes tiveram alterações obstrutivas relatadas em seus testes de função pulmonar (dois tiveram alterações moderadamente graves e um teve alterações obstrutivas leves. Não houve correlação entre os parâmetros da função pulmonar e as medidas antropométricas. CONCLUSÃO: Esses dados mostram que os parâmetros do teste da função pulmonar em crianças com obesidade leve foram semelhantes àqueles das crianças com peso normal. As medidas antropométricas não mostraram nenhum efeito significativo nas medições espirométricas das crianças, como ocorreu nos adultos.OBJECTIVE: Although obesity was found to be associated with severe impairment of ventilation, most of the study population has been morbidly obese adults. We aimed to explore the effects of mild obesity on ventilatory function in the pediatric age group. METHODS: In a cross-sectional controlled study, 80 patients (M/F: 35/45, who were evaluated in our outpatient clinic with the complaint

  4. LACTATE AND VENTILATORY THRESHOLDS REFLECT THE TRAINING STATUS OF PROFESSIONAL SOCCER PLAYERS WHERE MAXIMUM AEROBIC POWER IS UNCHANGED

    Directory of Open Access Journals (Sweden)

    N Clark

    2003-03-01

    Full Text Available The aim of this study was to investigate maximum aerobic power (VO2 max and anaerobic threshold (AT as determinants of training status among professional soccer players. Twelve professional 1st team British male soccer players (age: 26.2 ± 3.3 years, height: 1.77 ± 0.05 m, body mass: 79.3 ± 9.4 kg agreed to participate in the study and provided informed consent. All subjects completed a combined test of anaerobic threshold (AT and maximum aerobic power on two occasions: Test 1 following 5 weeks of low level activity at the end of the off-season and Test 2 immediately following conclusion of the competitive season. AT was assessed as both lactate threshold (LT and ventilatory threshold (VT. There was no change in VO2 max between Test 1 and Test 2 (63.3 ± 5.8 ml·kg-1·min-1 vs. 62.1 ± 4.9 ml·kg-1·min-1 respectively, however, the duration of exercise tolerance (ET at VO2 max was significantly extended from Test 1 to Test 2 (204 ± 54 vs. 228 ± 68 s respectively (P<0.01. LT oxygen consumption was significantly improved in Test 2 versus Test 1 (P<0.01 VT was also improved (P<0.05. There was no significant difference in VO2 (ml·kg-1·min-1 corresponding to LT and VT. The results of this study show that VO2 max is a less sensitive indicator to changes in training status in professional soccer players than either LT or VT.

  5. Validity of electromyographic fatigue threshold as a noninvasive method for tracking changes in ventilatory threshold in college-aged men.

    Science.gov (United States)

    Kendall, Kristina L; Smith, Abbie E; Graef, Jennifer L; Walter, Ashley A; Moon, Jordan R; Lockwood, Christopher M; Beck, Travis W; Cramer, Joel T; Stout, Jeffrey R

    2010-01-01

    The submaximal electromyographic fatigue threshold test (EMG(FT)) has been shown to be highly correlated to ventilatory threshold (VT) as determined from maximal graded exercise tests (GXTs). Recently, a prediction equation was developed using the EMG(FT) value to predict VT. The aim of this study, therefore, was to determine if this new equation could accurately track changes in VT after high-intensity interval training (HIIT). Eighteen recreationally trained men (mean +/- SD; age 22.4 +/- 3.2 years) performed a GXT to determine maximal oxygen consumption rate (V(O2)peak) and VT using breath-by-breath spirometry. Participants also completed a discontinuous incremental cycle ergometer test to determine their EMGFT value. A total of four 2-minute work bouts were completed to obtain 15-second averages of the electromyographic amplitude. The resulting slopes from each successive work bout were used to calculate EMG(FT). The EMG(FT) value from each participant was used to estimate VT from the recently developed equation. All participants trained 3 days a week for 6 weeks. Training consisted of 5 sets of 2-minute work bouts with 1 minute of rest in between. Repeated-measures analysis of variance indicated no significant difference between actual and predicted VT values after 3 weeks of training. However, there was a significant difference between the actual and predicted VT values after 6 weeks of training. These findings suggest that the EMG(FT) may be useful when tracking changes in VT after 3 weeks of HIIT in recreationally trained individuals. However, the use of EMG(FT) to predict VT does not seem to be valid for tracking changes after 6 weeks of HIIT. At this time, it is not recommended that EMG(FT) be used to predict and track changes in VT.

  6. Metric-adjusted skew information

    DEFF Research Database (Denmark)

    Liang, Cai; Hansen, Frank

    2010-01-01

    We give a truly elementary proof of the convexity of metric-adjusted skew information following an idea of Effros. We extend earlier results of weak forms of superadditivity to general metric-adjusted skew information. Recently, Luo and Zhang introduced the notion of semi-quantum states...... on a bipartite system and proved superadditivity of the Wigner-Yanase-Dyson skew informations for such states. We extend this result to the general metric-adjusted skew information. We finally show that a recently introduced extension to parameter values 1 information is a special case...... of (unbounded) metric-adjusted skew information....

  7. Convexity Adjustments for ATS Models

    DEFF Research Database (Denmark)

    Murgoci, Agatha; Gaspar, Raquel M.

    Practitioners are used to value a broad class of exotic interest rate derivatives simply by preforming for what is known as convexity adjustments (or convexity corrections). We start by exploiting the relations between various interest rate models and their connections to measure changes. As a re......Practitioners are used to value a broad class of exotic interest rate derivatives simply by preforming for what is known as convexity adjustments (or convexity corrections). We start by exploiting the relations between various interest rate models and their connections to measure changes....... As a result we classify convexity adjustments into forward adjustments and swaps adjustments. We, then, focus on affine term structure (ATS) models and, in this context, conjecture convexity adjustments should be related of affine functionals. In the case of forward adjustments, we show how to obtain exact...... formulas. Concretely for LIBOR in arrears (LIA) contracts, we derive the system of Riccatti ODE-s one needs to compute to obtain the exact adjustment. Based upon the ideas of Schrager and Pelsser (2006) we are also able to derive general swap adjustments useful, in particular, when dealing with constant...

  8. Adjustment computations spatial data analysis

    CERN Document Server

    Ghilani, Charles D

    2011-01-01

    the complete guide to adjusting for measurement error-expanded and updated no measurement is ever exact. Adjustment Computations updates a classic, definitive text on surveying with the latest methodologies and tools for analyzing and adjusting errors with a focus on least squares adjustments, the most rigorous methodology available and the one on which accuracy standards for surveys are based. This extensively updated Fifth Edition shares new information on advances in modern software and GNSS-acquired data. Expanded sections offer a greater amount of computable problems and their worked solu

  9. Hearing Assistive Technology

    Science.gov (United States)

    ... for the Public / Hearing and Balance Hearing Assistive Technology Hearing Assistive Technology: FM Systems | Infrared Systems | Induction ... Assistive Technology Systems Solutions What are hearing assistive technology systems (HATS)? Hearing assistive technology systems (HATS) are ...

  10. Spousal Adjustment to Myocardial Infarction.

    Science.gov (United States)

    Ziglar, Elisa J.

    This paper reviews the literature on the stresses and coping strategies of spouses of patients with myocardial infarction (MI). It attempts to identify specific problem areas of adjustment for the spouse and to explore the effects of spousal adjustment on patient recovery. Chapter one provides an overview of the importance in examining the…

  11. Mood Adjustment via Mass Communication.

    Science.gov (United States)

    Knobloch, Silvia

    2003-01-01

    Proposes and experimentally tests mood adjustment approach, complementing mood management theory. Discusses how results regarding self-exposure across time show that patterns of popular music listening among a group of undergraduate students differ with initial mood and anticipation, lending support to mood adjustment hypotheses. Describes how…

  12. A complete generalized adjustment criterion

    NARCIS (Netherlands)

    Perković, Emilija; Textor, Johannes; Kalisch, Markus; Maathuis, Marloes H.

    2015-01-01

    Covariate adjustment is a widely used approach to estimate total causal effects from observational data. Several graphical criteria have been developed in recent years to identify valid covariates for adjustment from graphical causal models. These criteria can handle multiple causes, latent confound

  13. Bayes linear covariance matrix adjustment

    CERN Document Server

    Wilkinson, Darren J

    1995-01-01

    In this thesis, a Bayes linear methodology for the adjustment of covariance matrices is presented and discussed. A geometric framework for quantifying uncertainties about covariance matrices is set up, and an inner-product for spaces of random matrices is motivated and constructed. The inner-product on this space captures aspects of our beliefs about the relationship between covariance matrices of interest to us, providing a structure rich enough for us to adjust beliefs about unknown matrices in the light of data such as sample covariance matrices, exploiting second-order exchangeability and related specifications to obtain representations allowing analysis. Adjustment is associated with orthogonal projection, and illustrated with examples of adjustments for some common problems. The problem of adjusting the covariance matrices underlying exchangeable random vectors is tackled and discussed. Learning about the covariance matrices associated with multivariate time series dynamic linear models is shown to be a...

  14. Parental Divorce and Children's Adjustment.

    Science.gov (United States)

    Lansford, Jennifer E

    2009-03-01

    This article reviews the research literature on links between parental divorce and children's short-term and long-term adjustment. First, I consider evidence regarding how divorce relates to children's externalizing behaviors, internalizing problems, academic achievement, and social relationships. Second, I examine timing of the divorce, demographic characteristics, children's adjustment prior to the divorce, and stigmatization as moderators of the links between divorce and children's adjustment. Third, I examine income, interparental conflict, parenting, and parents well-being as mediators of relations between divorce and children's adjustment. Fourth, I note the caveats and limitations of the research literature. Finally, I consider notable policies related to grounds for divorce, child support, and child custody in light of how they might affect children s adjustment to their parents divorce.

  15. Assistive Devices

    Science.gov (United States)

    ... a number of assistive devices. These are tools, products or types of equipment that help you perform tasks and activities. They may help you move around, see, communicate, eat, or get dressed. Some are high-tech tools, such as computers. Others are much simpler, ...

  16. Teaching Assistants.

    Science.gov (United States)

    Feinman, Jay M.

    1991-01-01

    A discussion of teaching assistants (TAs) in the law school looks at the TA's cognitive and affective roles and effective ways to use TAs to reinforce usual forms of learning in the large class; introduce a broadened range of materials, skills, and learning methods; and transform the large class experience. (MSE)

  17. Managing psychosocial adjustment to aphasia.

    Science.gov (United States)

    Müller, D

    1999-01-01

    This article argues for incorporating psychosocial adjustment into treatment plans for people with aphasia. It proposes that rehabilitation is a social rather than a medical construct and that by adopting a broad range of intervention strategies, more effective approaches to reintegration can be adopted. Outcome measures relating to self-esteem are judged to be central to evaluating the efficacy of treatment. The role of social factors in managing psychosocial adjustment are considered alongside individual and family approaches to counseling. It is concluded that clinicians need to broaden their treatment program to include psychosocial adjustment in rehabilitation.

  18. Yuan Exchange Rate 'Properly Adjusted'

    Institute of Scientific and Technical Information of China (English)

    2005-01-01

      The currency exchange rate was "properly adjusted" this year and takes into account effects on the country's neighbors and the world, Premier Wen Jiabao said at a regional meeting in Malaysia.……

  19. Adjustable Induction-Heating Coil

    Science.gov (United States)

    Ellis, Rod; Bartolotta, Paul

    1990-01-01

    Improved design for induction-heating work coil facilitates optimization of heating in different metal specimens. Three segments adjusted independently to obtain desired distribution of temperature. Reduces time needed to achieve required temperature profiles.

  20. Adjustable chain trees for proteins

    DEFF Research Database (Denmark)

    Winter, Pawel; Fonseca, Rasmus

    2012-01-01

    A chain tree is a data structure for changing protein conformations. It enables very fast detection of clashes and free energy potential calculations. A modified version of chain trees that adjust themselves to the changing conformations of folding proteins is introduced. This results in much...... tighter bounding volume hierarchies and therefore fewer intersection checks. Computational results indicate that the efficiency of the adjustable chain trees is significantly improved compared to the traditional chain trees....

  1. Adjusting to Chronic Health Conditions.

    Science.gov (United States)

    Helgeson, Vicki S; Zajdel, Melissa

    2017-01-03

    Research on adjustment to chronic disease is critical in today's world, in which people are living longer lives, but lives are increasingly likely to be characterized by one or more chronic illnesses. Chronic illnesses may deteriorate, enter remission, or fluctuate, but their defining characteristic is that they persist. In this review, we first examine the effects of chronic disease on one's sense of self. Then we review categories of factors that influence how one adjusts to chronic illness, with particular emphasis on the impact of these factors on functional status and psychosocial adjustment. We begin with contextual factors, including demographic variables such as sex and race, as well as illness dimensions such as stigma and illness identity. We then examine a set of dispositional factors that influence chronic illness adjustment, organizing these into resilience and vulnerability factors. Resilience factors include cognitive adaptation indicators, personality variables, and benefit-finding. Vulnerability factors include a pessimistic attributional style, negative gender-related traits, and rumination. We then turn to social environmental variables, including both supportive and unsupportive interactions. Finally, we review chronic illness adjustment within the context of dyadic coping. We conclude by examining potential interactions among these classes of variables and outlining a set of directions for future research.

  2. Cell and Tissue Organization in the Circulatory and Ventilatory Systems Volume 1 Signaling in Cell Organization, Fate, and Activity, Part A Cell Structure and Environment

    CERN Document Server

    Thiriet, Marc

    2011-01-01

    The volumes in this authoritative series present a multidisciplinary approach to modeling and simulation of flows in the cardiovascular and ventilatory systems, especially multiscale modeling and coupled simulations. The cardiovascular and respiratory systems are tightly coupled, as their primary function is to supply oxygen to and remove carbon dioxide from the body's cells. Because physiological conduits have deformable and reactive walls, macroscopic flow behavior and prediction must be coupled to nano- and microscopic events in a corrector scheme of regulated mechanisms. Therefore, investigation of flows of blood and air in physiological conduits requires an understanding of the biology, chemistry, and physics of these systems together with the mathematical tools to describe their functioning.  The present volume is devoted to cellular events that allow adaptation to environmental conditions, particularly mechanotransduction. It begins with cell organization and a survey of cell types in the vasculatur...

  3. MCCB warm adjustment testing concept

    Science.gov (United States)

    Erdei, Z.; Horgos, M.; Grib, A.; Preradović, D. M.; Rodic, V.

    2016-08-01

    This paper presents an experimental investigation in to operating of thermal protection device behavior from an MCCB (Molded Case Circuit Breaker). One of the main functions of the circuit breaker is to assure protection for the circuits where mounted in for possible overloads of the circuit. The tripping mechanism for the overload protection is based on a bimetal movement during a specific time frame. This movement needs to be controlled and as a solution to control this movement we choose the warm adjustment concept. This concept is meant to improve process capability control and final output. The warm adjustment device design will create a unique adjustment of the bimetal position for each individual breaker, determined when the testing current will flow thru a phase which needs to trip in a certain amount of time. This time is predetermined due to scientific calculation for all standard types of amperages and complies with the IEC 60497 standard requirements.

  4. 75 FR 25103 - Tree Assistance Program

    Science.gov (United States)

    2010-05-07

    ..., Conservation, and Energy Act of 2008 (the 2008 Farm Bill). TAP provides disaster assistance to eligible... which there were mortality losses in excess of 15 percent, after adjustment for normal mortality, are... authorized by the 2008 Farm Bill (Pub. L. 110-246). Sections 12033 and 15101 of the 2008 Farm Bill...

  5. Congenital anomalies after assisted reproductive technology

    DEFF Research Database (Denmark)

    Pinborg, Anja; Henningsen, Anna-Karina Aaris; Malchau, Sara Sofie

    2013-01-01

    Worldwide, more than 5 million children have been born after assisted reproductive technology (ART), and in many developed countries ART infants represent more than 1% of the birth cohorts. It is well known that ART children are at increased risk of congenital malformations even after adjustment ...

  6. The effect of combined glutamate receptor blockade in the NTS on the hypoxic ventilatory response in awake rats differs from the effect of individual glutamate receptor blockade.

    Science.gov (United States)

    Pamenter, Matthew E; Nguyen, Jetson; Carr, John A; Powell, Frank L

    2014-08-01

    Ventilatory acclimatization to hypoxia (VAH) increases the hypoxic ventilatory response (HVR) and causes persistent hyperventilation when normoxia is restored, which is consistent with the occurrence of synaptic plasticity in acclimatized animals. Recently, we demonstrated that antagonism of individual glutamate receptor types (GluRs) within the nucleus tractus solitarii (NTS) modifies this plasticity and VAH (J. Physiol. 592(8):1839-1856); however, the effects of combined GluR antagonism remain unknown in awake rats. To evaluate this, we exposed rats to room air or chronic sustained hypobaric hypoxia (CSH, PiO2 = 70 Torr) for 7-9 days. On the experimental day, we microinjected artificial cerebrospinal fluid (ACSF: sham) and then a "cocktail" of the GluR antagonists MK-801 and DNQX into the NTS. The location of injection sites in the NTS was confirmed by glutamate injections on a day before the experiment and with histology following the experiment. Ventilation was measured in awake, unrestrained rats breathing normoxia or acute hypoxia (10% O2) in 15-min intervals using barometric pressure plethysmography. In control (CON) rats, acute hypoxia increased ventilation; NTS microinjections of GluR antagonists, but not ACSF, significantly decreased ventilation and breathing frequency in acute hypoxia but not normoxia (P NTS significantly decreased ventilation in normoxia and breathing frequency in hypoxia. A persistent HVR after combined GluR blockade in the NTS contrasts with the effect of individual GluR blockade and also with results in anesthetized rats. Our findings support the hypotheses that GluRs in the NTS contribute to, but cannot completely explain, VAH in awake rats.

  7. Tax Adjusted for Imported Equipment

    Institute of Scientific and Technical Information of China (English)

    2010-01-01

    @@ Ministry of Finance, Central Administration of Customs, and State Administration of Taxation of P.R. of China jointly issued a "Notice on the Lists Related to the Interim Provisions on the Adjustment of Import Tax Policy on Major Technical Equipment" (the Notice) on April 13rd to adjust the list of equipment catalog and merchandise attached to the "Interim Provisions on the Import Tax Policy on Major Technical Equipment", as well as the preferential scope and extent of the import tax on a number of major technical equipment.

  8. 77 FR 12007 - Notice of Petitions by Firms tor Determination of Eligibility to Apply For Trade Adjustment...

    Science.gov (United States)

    2012-02-28

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF COMMERCE Economic Development Administration Notice of Petitions by Firms tor Determination of Eligibility to Apply For Trade Adjustment Assistance AGENCY: Economic Development Administration, Department of...

  9. An adjustable contracted CI method

    Institute of Scientific and Technical Information of China (English)

    王育彬; 甘正汀; 苏克和; 文振翼

    1999-01-01

    A new contracted CI scheme——adjustable contracted CI scheme——is presented and programed. The efficiency of this scheme is tested by some example calculations. The result shows that the application of the new scheme is flexible and the correlation energy loss is lower than that of the original externally contracted CI method.

  10. Adjustment or updating of models

    Indian Academy of Sciences (India)

    D J Ewins

    2000-06-01

    In this paper, first a review of the terminology used in the model adjustment or updating is presented. This is followed by an outline of the major updating algorithms cuurently available, together with a discussion of the advantages and disadvantages of each, and the current state-of-the-art of this important application and part of optimum design technology.

  11. Ventilatory and ECMO treatment of H1N1-induced severe respiratory failure: results of an Italian referral ECMO center

    Directory of Open Access Journals (Sweden)

    Giovannini Valtere

    2011-01-01

    Full Text Available Abstract Background Since the first outbreak of a respiratory illness caused by H1N1 virus in Mexico, several reports have described the need of intensive care or extracorporeal membrane oxygenation (ECMO assistance in young and often healthy patients. Here we describe our experience in H1N1-induced ARDS using both ventilation strategy and ECMO assistance. Methods Following Italian Ministry of Health instructions, an Emergency Service was established at the Careggi Teaching Hospital (Florence, Italy for the novel pandemic influenza. From Sept 09 to Jan 10, all patients admitted to our Intensive Care Unit (ICU of the Emergency Department with ARDS due to H1N1 infection were studied. All ECMO treatments were veno-venous. H1N1 infection was confirmed by PCR assayed on pharyngeal swab, subglottic aspiration and bronchoalveolar lavage. Lung pathology was evaluated daily by lung ultrasound (LUS examination. Results A total of 12 patients were studied: 7 underwent ECMO treatment, and 5 responded to protective mechanical ventilation. Two patients had co-infection by Legionella Pneumophila. One woman was pregnant. In our series, PCR from bronchoalveolar lavage had a 100% sensitivity compared to 75% from pharyngeal swab samples. The routine use of LUS limited the number of chest X-ray examinations and decreased transportation to radiology for CT-scan, increasing patient safety and avoiding the transitory disconnection from ventilator. No major complications occurred during ECMO treatments. In three cases, bleeding from vascular access sites due to heparin infusion required blood transfusions. Overall mortality rate was 8.3%. Conclusions In our experience, early ECMO assistance resulted safe and feasible, considering the life threatening condition, in H1N1-induced ARDS. Lung ultrasound is an effective mean for daily assessment of ARDS patients.

  12. 24 CFR 884.109 - Rent adjustments.

    Science.gov (United States)

    2010-04-01

    ... assisted and comparable unassisted units, as determined by HUD: Provided, however, That this limitation shall not be construed to prohibit differences in rents between assisted and comparable unassisted...

  13. Adjustable wheelchair and method for adjusting said adjustable wheelchair, and wheelchair assembly

    NARCIS (Netherlands)

    Oosterhuis, D.S.

    2013-01-01

    The invention relates to an adjustable wheelchair comprising: -a carriage; -two rear wheels; -at least one front wheel; -at least one footrest; -a sub-frame; -a seat; and -a backrest; wherein the two rear wheels, the at least one front wheel and the at least one footrest are mounted to the carriage,

  14. Uncertainty-based Estimation of the Secure Range for ISO New England Dynamic Interchange Adjustment

    Energy Technology Data Exchange (ETDEWEB)

    Etingov, Pavel V.; Makarov, Yuri V.; Wu, Di; Hou, Zhangshuan; Sun, Yannan; Maslennikov, S.; Luo, Xiaochuan; Zheng, T.; George, S.; Knowland, T.; Litvinov, E.; Weaver, S.; Sanchez, E.

    2014-04-14

    The paper proposes an approach to estimate the secure range for dynamic interchange adjustment, which assists system operators in scheduling the interchange with neighboring control areas. Uncertainties associated with various sources are incorporated. The proposed method is implemented in the dynamic interchange adjustment (DINA) tool developed by Pacific Northwest National Laboratory (PNNL) for ISO New England. Simulation results are used to validate the effectiveness of the proposed method.

  15. Inspiratory-resistive loading increases the ventilatory response to arousal but does not reduce genioglossus muscle activity on the return to sleep.

    Science.gov (United States)

    Cori, Jennifer M; Nicholas, Christian L; Baptista, Shaira; Huynh, Ivan; Rochford, Peter D; O'Donoghue, Fergal J; Trinder, John A; Jordan, Amy S

    2012-09-01

    Arousals from sleep are thought to predispose to obstructive sleep apnea by causing hyperventilation and hypocapnia, which reduce airway dilator muscle activity on the return to sleep. However, prior studies of auditory arousals have not resulted in reduced genioglossus muscle activity [GG-electromyogram (EMG)], potentially because airway resistance prior to arousal was low, leading to a small ventilatory response to arousal and minimal hypocapnia. Thus we aimed to increase the ventilatory response to arousal by resistive loading prior to auditory arousal and determine whether reduced GG-EMG occurred on the return to sleep. Eighteen healthy young men and women were recruited. Subjects were instrumented with a nasal mask with a pneumotachograph, an epiglottic pressure catheter, and intramuscular GG-EMG electrodes. Mask CO(2) levels were monitored. Three- to 15-s arousals from sleep were induced with auditory tones after resting breathing (No-Load) or inspiratory-resistive loading (Load; average 8.4 cmH(2)O·l(-1)·s(-1)). Peak minute ventilation following arousal was greater after Load than No-Load (mean ± SE; 8.0 ± 0.6 vs. 7.4 ± 0.6 l/min, respectively). However, the nadir end tidal partial pressure of CO(2) did not differ between Load conditions (43.1 ± 0.6 and 42.8 ± 0.5 mmHg, respectively), and no period of reduced GG activity occurred following the return to sleep (GG-EMG baseline, minimum after Load and No-Load = 2.9 ± 1.2%, 3.1 ± 1.3%, and 3.0 ± 1.3% max, respectively). These findings indicate that the hyperventilation, which occurs following tone-induced arousal, is appropriate for the prevailing level of respiratory drive, because loading did not induce marked hypocapnia or lower GG muscle activity on the return to sleep. Whether similar findings occur following obstructive events in patients remains to be determined.

  16. A simplified approach to assess variations in Eustachian tubal ventilatory function by Bortnick-Miller apparatus in chronic otitis media cases (dry before surgery

    Directory of Open Access Journals (Sweden)

    Apoorva Kumar Pandey

    2011-01-01

    Full Text Available Aim: The aim of this study is to see the different functional gradings of Eustachian tube ventilatory function as assessed by Bortnick-Miller (B-M apparatus in chronically diseased middle ears (dry cases planned to undergo tympanoplasty and to correlate the results with the past experiences. Materials and Methods: This study consisted of 29 cases of chronic suppurative otitis media, inactive stage having central perforation. Tubal function was evaluated by B-M apparatus based on ability of tube assimilating the applied positive and negative pressure. Tubal opening pressure was noted after applying positive pressure while residual intratympanic pressure after 10 swallows was recorded after applying negative pressure. Results: This study revealed that results of tubal manometry in diseased ears cover a wide spectrum of normal function to partial/non-function. 51.72% of cases were able to equalize applied negative pressure, 41.39% partially equalizing, while 6.89% of cases were completely unable to equalize applied negative pressure. Conclusion: Our results of aspiration method with the help of BM apparatus explicitly suggest that tubal function in chronically diseased ears deviates from that of normal ears. It perpetually reflects that varied results of middle ear reconstructive surgeries could be anticipated in accordance with different tubal function gradings.

  17. Comparison between two different modes of non-invasive ventilatory support in preterm newborn infants with respiratory distress syndrome mild to moderate: preliminary data

    Directory of Open Access Journals (Sweden)

    F. Ciuffini

    2014-08-01

    Full Text Available Despite of improved survival of premature infants, the incidence of long term pulmonary complications, mostly associated with ventilation-induced lung injury, remains high. Non invasive ventilation (NIV is able to reduce the adverse effects of mechanical ventilation. Although nasal continuous positive airway pressure (NCPAP is an effective mode of NIV, traumatic nasal complications and intolerance of the nasal interface are common. Recently high flow nasal cannula (HFNC is emerging as a better tolerated form of NIV, allowing better access to the baby’s face, which may improve nursing, feeding and bonding. HFNC may be effective in the treatment of some neonatal respiratory conditions while being more user-friendly for care-givers than conventional NCPAP. Limited evidence is available to support the specific role, efficacy and safety of HFNC in newborns and to demonstrate efficacy compared with NCPAP; some studies suggest a potential role for HFNC in respiratory care of the neonate as a distinct non invasive ventilatory support. We present the preliminary data of a randomized clinical trial; the aim of this study was to assess efficacy and safety of HFNC compared to NCPAP in preterm newborns with mild to moderate respiratory distress syndrome (RDS.

  18. The use of near infrared spectroscopy (NIRS) to determine the ventilatory threshold and the relation between skeletal muscle oxygenation and RPE

    Science.gov (United States)

    Tessmer, Kathryn Anne

    This study: (1) compared three (i.e., V-slope, Bhambhani et al., 1997, and Belardinelli et al., 1995) techniques of measuring the ventilatory threshold (VT), (2) examined the relation between OMNI RPE and muscle deoxygenation (MD), and (3) evaluated the impact of gender on MD and RPE. Subjects included 20 males and 13 females, aged 25-29 years. A commercial NIRS sensor (NIRS Micro-Run Man model # MRM-96) was placed over the right vastus lateralis and secured with an elastic wrap. Next, each subject underwent a progressive multistage cycle ergometer test to establish the VT using the V-slope method and NIRS methods. The V-slope (58.62 +/- 10.47% VO2peak), Bhambhani et al. 1997 (49.75 +/- 20.13% VO2peak), and Belardinelli et al. 1995 (60.87 +/- 10.15% VO2peak) methods did not result in different (F(2,49) = 2.77, p > 0.05) VT values. The following significant linear regression equation was generated (p = 0.016): OMNI RPE = 5.97 - (15.20)MD (R = -0.20, R 2 = 0.04, and SE = 2.76). The two-way ANOVA (gender x power output) conducted on OMNI RPE revealed a significant main effect for gender ( F(1,193) = 19.53, p cycle ergometer protocol.

  19. First Year Adjustment in the Secondary School.

    Science.gov (United States)

    Loosemore, Jean Ann

    1978-01-01

    This study investigated the relationship between adjustment to secondary school and 17 cognitive and noncognitive variables, including intelligence (verbal and nonverbal reasoning), academic achievement, extraversion-introversion, stable/unstable, social adjustment, endeavor, age, sex, and school form. (CP)

  20. Theory of Work Adjustment Personality Constructs.

    Science.gov (United States)

    Lawson, Loralie

    1993-01-01

    To measure Theory of Work Adjustment personality and adjustment style dimensions, content-based scales were analyzed for homogeneity and successively reanalyzed for reliability improvement. Three sound scales were developed: inflexibility, activeness, and reactiveness. (SK)

  1. Research Design in Marital Adjustment Studies.

    Science.gov (United States)

    Croake, James W.; Lyon, Rebecca S.

    1978-01-01

    The numerous marital adjustment studies which exist in the literature are confounded by basic design problems. Marital stability should be the baseline for data. It is then possible to discuss "happiness,""success,""adjustment," and "satisfaction." (Author)

  2. Capital adjustment patterns on Dutch pig farms

    NARCIS (Netherlands)

    Gardebroek, C.

    2004-01-01

    This paper develops a generalised adjustment cost framework that explicitly accounts for zero investments on Dutch pig farms. A farm-specific flexible adjustment cost function is used to account for differences in adjustment costs between farms. Using the Generalised Method of Moments the Euler equa

  3. Reexpansion Pulmonary Edema following Laparoscopy-Assisted Distal Gastrectomy for a Patient with Early Gastric Cancer: A Case Report

    Directory of Open Access Journals (Sweden)

    Kazuhito Yajima

    2012-01-01

    Full Text Available We report here a case of reexpansion pulmonary edema following laparoscopy-assisted distal gastrectomy (LADG for early gastric cancer. A 57-year-old Japanese woman with no preoperative comorbidity was diagnosed with early gastric cancer. The patient underwent LADG using the pneumoperitoneum method. During surgery, the patient was unintentionally subjected to single-lung ventilation for approximately 247 minutes due to intratracheal tube dislocation. One hour after surgery, she developed severe dyspnea and produced a large amount of pink frothy sputum. Chest radiography results showed diffuse ground-glass attenuation and alveolar consolidation in both lungs without cardiomegaly. A diagnosis of pulmonary edema was made, and the patient was immediately intubated and received ventilatory support with high positive end-expiratory pressure. The patient gradually recovered and was weaned from the ventilatory support on the third postoperative day. This case shows that single-lung ventilation may be a risk factor for reexpansion pulmonary edema during laparoscopic surgery with pneumoperitoneum.

  4. Psychosocial adjustment to recurrent cancer.

    Science.gov (United States)

    Mahon, S M; Cella, D F; Donovan, M I

    1990-01-01

    This descriptive study of the perceptions and needs of people with recurrent malignancies asks three questions: How do patients describe the meaning of a recurrence of cancer? Do individuals perceive the diagnosis of recurrence and the initial diagnosis of cancer differently? What are the key psychosocial problems associated with recurrent cancer? The theoretical framework was based on Lazarus and Folkman's theory of stress, appraisal, and coping. Subjects completed the Impact of Event Scale (IES), the Psychosocial Adjustment to Illness Scale--Self-Report (PAIS), and a semistructured qualitative interview. The interview elicited perceptions of the event of recurrence and differences between the diagnosis of recurrence and the initial diagnosis. The convenience sample included 40 patients diagnosed with recurrent cancer within the last 30 days. Many subjects (78%) reported that the recurrence was more upsetting than the initial diagnosis. Scores on both the IES and the PAIS were high when compared to normative samples of patients with cancer suggesting that this sample of patients experienced a lot of psychological distress as well as problems at home, work, and in their social lives. These concerns often were unknown to caregivers. Although more research is needed, the authors propose that, with more accurate assessment, more effective intervention could be implemented and the quality of life improved for patients with recurrent cancer.

  5. Control of Adjustable Compliant Actuators

    Directory of Open Access Journals (Sweden)

    Berno J.E. Misgeld

    2014-05-01

    Full Text Available Adjustable compliance or variable stiffness actuators comprise an additional element to elastically decouple the actuator from the load and are increasingly applied to human-centered robotic systems. The advantages of such actuators are of paramount importance in rehabilitation robotics, where requirements demand safe interaction between the therapy system and the patient. Compliant actuator systems enable the minimization of large contact forces arising, for example, from muscular spasticity and have the ability to periodically store and release energy in cyclic movements. In order to overcome the loss of bandwidth introduced by the elastic element and to guarantee a higher range in force/torque generation, new actuator designs consider variable or nonlinear stiffness elements, respectively. These components cannot only be adapted to the walking speed or the patient condition, but also entail additional challenges for feedback control. This paper introduces a novel design method for an impedance-based controller that fulfills the control objectives and compares the performance and robustness to a classical cascaded control approach. The new procedure is developed using a non-standard positive-real Η2 controller design and is applied to a loop-shaping approach. Robust norm optimal controllers are designed with regard to the passivity of the actuator load-impedance transfer function and the servo control problem. Classical cascaded and positive-real Η2 controller designs are validated and compared in simulations and in a test bench using a passive elastic element of varying stiffness.

  6. Adaptation and adjustment in children of transsexual parents.

    Science.gov (United States)

    White, Tonya; Ettner, Randi

    2007-06-01

    It is a relatively uncommon event that children find themselves in a situation with a parent who undergoes a transition from one sex to another. Unlike situations of divorce or a parent with a medical or major psychiatric disorder, it is unlikely that the children will know of other children who encounter similar situations. There is very little literature that describes the adjustment of these children and the nature of their relationships with their parents and peers. Such information would be beneficial for clinicians assisting children and families in this situation. To better delineate the adjustment of these children, we interviewed 27 parents of 55 children. The interview took place on average 6 years after the gender transition. The measures obtained included the parent and child relationships at present and also at the time of the transition. We also inquired about academic function, peer relationships and social stigma. The results found that children who were younger at the time of the parent's transition tended to have better relationships and less adjustment difficulties. In addition, parental conflict that continues after the transition period tends to reflect greater family conflict between the transitioned parent and their child.

  7. ForeignAssistance.gov

    Data.gov (United States)

    US Agency for International Development — ForeignAssistance.gov provides a view of U.S. Government foreign assistance funds across agencies and enables users to explore, analyze, and review aid investments...

  8. Assistência ventilatória domiciliar em crianças: descrição de um programa Home ventilation of pediatric patients: description of a program

    Directory of Open Access Journals (Sweden)

    Tânia D. Resener

    2001-04-01

    Full Text Available OBJETIVO: o número de pacientes pediátricos dependentes de suporte ventilatório vem aumentando de maneira relevante nas últimas décadas. Essas crianças permanecem por longos períodos internadas, freqüentemente em unidades de terapia intensiva. Para minimizar as hospitalizações, tem sido dada ênfase à continuação da terapia ventilatória no domicílio. No presente trabalho descreve-se um programa de assistência ventilatória domiciliar desenvolvido na Alemanha, visando antever a possibilidade de adaptação à nossa realidade. CASUÍSTICA E METODOLOGIA: avaliou-se o programa de assistência ventilatória domiciliar da UTI-Pediátrica do Dr. von Haunersches Kinderklinik - Ludwig-Maximilians-Universität-München (Munique, Alemanha no período entre abril de 1997 e junho de 1998. RESULTADOS: o referido programa dá suporte a pacientes com idades entre 1 e 21 anos, sendo 11 do sexo masculino e 15 do feminino. Dos 26 pacientes, 15 apresentavam patologias neuromusculares, oito problemas ventilatórios de causa central e três doenças pulmonares obstrutivas. Doze crianças (46,2% eram ventiladas através de técnicas não-invasivas e 19 (73,1% necessitavam apenas de suporte ventilatório intermitente. CONCLUSÃO: o programa tem uma equipe multidisciplinar permanentemente responsável pelo tratamento de intercorrências. Os pacientes, em períodos pré-determinados, são submetidos a reavaliações da evolução da insuficiência respiratória. Essa organização do sistema faz com que paciente e familiares sintam-se seguros e é responsável pelo êxito do programa de assistência ventilatória no domicílio. Existe a necessidade de um grande esforço organizacional antes que possamos instituir programas semelhantes no Brasil.OBJECTIVE: to describe a German program for home ventilatory support, and to analyze the possibility of applying it in Brazil. MATERIALS AND METHODS: we assessed Dr. von Haunersches Kinderklinik’s Pediatric

  9. Ergonomic evaluation of the Apple Adjustable Keyboard

    Energy Technology Data Exchange (ETDEWEB)

    Tittiranonda, P.; Burastero, S.; Shih, M. [Lawrence Livermore National Lab., CA (United States); Rempel, D. [University of California Berkeley/San Francisco (United States). Ergonomics Laboratory

    1994-05-01

    This study presents an evaluation of the Apple Adjustable Keyboard based on subjective preference and observed joint angles during typing. Thirty five keyboard users were asked to use the Apple adjustable keyboard for 7--14 days and rate the various characteristics of the keyboard. Our findings suggest that the most preferred opening angles range from 11--20{degree}. The mean ulnar deviation on the Apple Adjustable keyboard is 11{degree}, compared to 16{degree} on the standard keyboard. The mean extension was decreased from 24{degree} to 16{degree} when using the adjustable keyboard. When asked to subjectively rate the adjustable keyboard in comparison to the standard, the average subject felt that the Apple Adjustable Keyboard was more comfortable and easier to use than the standard flat keyboard.

  10. Bias Adjusted Precipitation Threat Scores

    Directory of Open Access Journals (Sweden)

    F. Mesinger

    2008-04-01

    Full Text Available Among the wide variety of performance measures available for the assessment of skill of deterministic precipitation forecasts, the equitable threat score (ETS might well be the one used most frequently. It is typically used in conjunction with the bias score. However, apart from its mathematical definition the meaning of the ETS is not clear. It has been pointed out (Mason, 1989; Hamill, 1999 that forecasts with a larger bias tend to have a higher ETS. Even so, the present author has not seen this having been accounted for in any of numerous papers that in recent years have used the ETS along with bias "as a measure of forecast accuracy".

    A method to adjust the threat score (TS or the ETS so as to arrive at their values that correspond to unit bias in order to show the model's or forecaster's accuracy in extit{placing} precipitation has been proposed earlier by the present author (Mesinger and Brill, the so-called dH/dF method. A serious deficiency however has since been noted with the dH/dF method in that the hypothetical function that it arrives at to interpolate or extrapolate the observed value of hits to unit bias can have values of hits greater than forecast when the forecast area tends to zero. Another method is proposed here based on the assumption that the increase in hits per unit increase in false alarms is proportional to the yet unhit area. This new method removes the deficiency of the dH/dF method. Examples of its performance for 12 months of forecasts by three NCEP operational models are given.

  11. Efficient Adjustable Reflectivity Smart Window

    Energy Technology Data Exchange (ETDEWEB)

    D. Morgan Tench

    2005-12-01

    This project addressed the key technical issues for development of an efficient smart window based on reversible electrochemical transfer of silver between a mirror electrode and a localized counter electrode. Effort to provide uniform switching over large areas focused on use of a resistive transparent electrode innerlayer to increase the interelectrode resistance. An effective edge seal was developed in collaboration with adhesive suppliers and an electrochromic device manufacturer. Work to provide a manufacturable counter electrode focused on fabricating a dot matrix electrode without photolithography by electrodeposition of Pt nuclei on inherent active sites on a transparent oxide conductor. An alternative counter electrode based on a conducting polymer and an ionic liquid electrolyte was also investigated. Work in all of these areas was successful. Sputtered large-bandgap oxide innerlayers sandwiched between conductive indium tin oxide (ITO) layers were shown to provide sufficient cross-layer resistance (>300 ohm/cm{sup 2}) without significantly affecting the electrochemical properties of the ITO overlayer. Two edge seal epoxies, one procured from an epoxy manufacturer and one provided by an electrochromic device manufacturer in finished seals, were shown to be effective barriers against oxygen intrusion up to 80 C. The optimum density of nuclei for the dot matrix counter electrode was attained without use of photolithography by electrodeposition from a commercial alkaline platinum plating bath. Silver loss issues for cells with dot matrix electrodes were successfully addressed by purifying the electrolyte and adjusting the cell cycling parameters. More than 30K cycles were demonstrated for a REM cell (30-cm square) with a dot matrix counter electrode. Larger cells (30-cm square) were successfully fabricated but could not be cycled since the nucleation layers (provided by an outside supplier) were defective so that mirror deposits could not be produced.

  12. The organization of anticipatory postural adjustments

    OpenAIRE

    Aruin Alexander S.

    2002-01-01

    Central control of posture is expressed through anticipatory and compensatory postural adjustments. Anticipatory postural adjustments (APAs) precede planned postural perturbations and minimize them with anticipatory corrections, while compensatory postural adjustments deal with actual perturbations of balance that occur as a result of suboptimal efficiency of anticipatory corrections. The process of generation of APAs is affected by three major factors: expected magnitude and direction of the...

  13. Development of Adjustable Grazing Incidence Optics

    Science.gov (United States)

    Reid, Paul B.; Davis, W.; Schwartz, D. A.; Trolier-McKinstry, S.; Wilke, R. H. T.

    2010-03-01

    We report on the development of adjustable grazing incidence optics. We are developing bimorph mirrors for high resolution (sub-arc second) imaging. Bimorph mirrors consist of a thin layer of piezo-electric material deposited on the back surface of a thin (material localizes the strain to the particular piezo "pixel.” Mirror figure errors are corrected (on-orbit) via induced localized deformations. We have successfully deposited a 1-micrometer thick layer of the piezo-electric material lead-zirconate-titanate (PZT) on thin glass mirrors. We report on the electrical and mechanical properties of the bimorph mirrors, and mirror requirements. We discuss finite element modeling of bimorph mirrors. In particular, we focus on how a difference in mirror mounting affects the influence functions ( the induced deformations). We are also developing the use of electrostrictive adjusters for moderate resolution (a few arc second) imaging. Electroplated nickel/cobalt full shells are mounted together using the adjusters. The adjusters are arrayed axially and tangentially between shells, with their adjustable dimension in the radial direction. Each shell is adjusted and fixed in place during mirror assembly, starting with the innermost shell. We review finite element modeling of the adjustable optics and the application of the adjustment system to correct manufacturing errors. We discuss initial tests using electrostrictive adjusters to change the shape of flat mirror segments. This work is supported by NASA Contract NNX09AE87G and a grant from the Gordon and Betty Moore Foundation.

  14. Ventilatory-perfusory pulmonary scintigraphy as non invasive election procedure in patients with clinical suspicion of pulmonary thrombo emboli; Centelleografia pulmonar ventilatoria-perfusoria, como procedimiento no invasivo de eleccion en pacientes con sospecha clinica de tromboembolia pulmonar

    Energy Technology Data Exchange (ETDEWEB)

    Altamirano L, J

    2004-07-01

    30 patients were studied with suspicion of pulmonary thrombo emboli PTE, in a period of 9 months (January-September of 1992), 20 women and 10 men, with an age range of 26 to 88 years, average of 57.59 18.89. With respect to the clinical data, 24 presented breathing inadequacy (80%). 16 tachycardia (54%), 15 with thoracic pain (50%) and 4 with hemoptysis (13%). Of the cabinet studies, 12 presented electrocardiographic changes (IF, QIII, and TIII) (40%), 14 presented abnormalities in arterial gases. In the thorax tele, 8 presented abnormality; as spill, pneumonia, diaphragmatic elevation, etc. (26.6%) and of 14 the result was not reported (46 6%). They were carried out in all the patients, the ventilatory studies and perfusories in that order. A Siemens mark scintillation camera was used, with a collimator of low energy and of high resolution; the information was stored in a floppy disk, and later on they were printed in radiographic plaques of high resolution. The ventilatory study was carried out with 30 mCi of {sup 99m} Tc-DTPA, in radio aerosol form, emitted by a micro nebulizer, to which was applied a pressure of oxygen of 10 ml-min; during 10 to 15 minutes. They took projections antero, posterior, oblique antero left and right, oblique posterior left and right, each one with an acquisition of 150000 counts, or during 5 minutes. Later on and remaining the patient in supine position, was carried out the perfusory study, applying 3-4 mCi of {sup 99} Tc-MAA for endo venous via; they took the same projections that the ventilatory study, but with a density of information greater (500 000 counts each one). Both studies are printed in a radiographic plaque of high resolution, with which is interpreted and the study is filed. (Author)

  15. Precision Adjustable Liquid Regulator (ALR)

    Science.gov (United States)

    Meinhold, R.; Parker, M.

    2004-10-01

    A passive mechanical regulator has been developed for the control of fuel or oxidizer flow to a 450N class bipropellant engine for use on commercial and interplanetary spacecraft. There are several potential benefits to the propulsion system, depending on mission requirements and spacecraft design. This system design enables more precise control of main engine mixture ratio and inlet pressure, and simplifies the pressurization system by transferring the function of main engine flow rate control from the pressurization/propellant tank assemblies, to a single component, the ALR. This design can also reduce the thermal control requirements on the propellant tanks, avoid costly Qualification testing of biprop engines for missions with more stringent requirements, and reduce the overall propulsion system mass and power usage. In order to realize these benefits, the ALR must meet stringent design requirements. The main advantage of this regulator over other units available in the market is that it can regulate about its nominal set point to within +/-0.85%, and change its regulation set point in flight +/-4% about that nominal point. The set point change is handled actively via a stepper motor driven actuator, which converts rotary into linear motion to affect the spring preload acting on the regulator. Once adjusted to a particular set point, the actuator remains in its final position unpowered, and the regulator passively maintains outlet pressure. The very precise outlet regulation pressure is possible due to new technology developed by Moog, Inc. which reduces typical regulator mechanical hysteresis to near zero. The ALR requirements specified an outlet pressure set point range from 225 to 255 psi, and equivalent water flow rates required were in the 0.17 lb/sec range. The regulation output pressure is maintained at +/-2 psi about the set point from a P (delta or differential pressure) of 20 to over 100 psid. Maximum upstream system pressure was specified at 320 psi

  16. Evaluation of an adjustable epidemiologic information system.

    Directory of Open Access Journals (Sweden)

    Jiunn-Shyan Julian Wu

    Full Text Available BACKGROUND: In order to facilitate public health response and to achieve early control of infectious disease epidemics, an adjustable epidemiologic information system (AEIS was established in the Taiwan public health network in February 2006. METHODOLOGY/PRINCIPAL FINDINGS: The performance of AEIS for the period 2006 through 2008 was evaluated based on a number of response times (RT and the public health impact. After implementation of the system, the apparent overall shortened RT was mainly due to the shortening of personnel response time (PRT and the time needed to draft a new questionnaire that incurred as personnel-system interface (PSI; PRT dropped from a fluctuating range of 9.8 ∼28.8 days in the first four months to <10 days in the following months and remained low till 2008 (0.88±1.52 days. The PSIs for newly emerged infectious diseases were 2.6 and 3.4 person-hours for H5N1 in 2007 and chikungunya in 2008, respectively, a much improvement from 1142.5 person-hours for SARS in 2003. The duration of each rubella epidemic cluster was evaluated as public health impact and showed a shortening trend (p = 0.019 that concurred with the shortening of PRT from 64.8±47.3 to 25.2±38.2 hours per cluster (p<0.0001. CONCLUSIONS/SIGNIFICANCE: The first evaluation of the novel instrument AEIS that had been used to assist Taiwan's multi-level government for infectious diseases control demonstrated that it was well integrated into the existing public health infrastructure. It provided flexible tools and computer algorithms with friendly interface for timely data collection, integration, and analysis; as a result, it shortened RTs, filled in gaps of personnel lacking sufficient experiences, created a more efficient flow of response, and identified asymptomatic/mild cases early to minimize further spreading. With further development, AEIS is anticipated to be useful in the application of other acute public health events needing immediate

  17. 76 FR 42140 - Rate Adjustment Remand

    Science.gov (United States)

    2011-07-18

    ... the plain meaning of the words ``due to'' in section 3622(d)(1)(E) requires a causal relationship... causal relationship between the amount of a requested adjustment and the exigent circumstances' impact on...'' phrase does not adequately express how close the relationship between the proposed adjustment and...

  18. 38 CFR 18.444 - Academic adjustments.

    Science.gov (United States)

    2010-07-01

    ... 38 Pensions, Bonuses, and Veterans' Relief 2 2010-07-01 2010-07-01 false Academic adjustments. 18.444 Section 18.444 Pensions, Bonuses, and Veterans' Relief DEPARTMENT OF VETERANS AFFAIRS (CONTINUED....444 Academic adjustments. (a) Academic requirements. A recipient shall make necessary modifications...

  19. Cultural Distance Asymmetry in Expatriate Adjustment

    DEFF Research Database (Denmark)

    Selmer, Jan; Chiu, Randy K.; Shenkar, Oded

    2007-01-01

    Purpose - The current literature implicitly assumes a symmetric impact of cultural distance (CD) on expatriate adjustment. By using distance as a predictor of adjustment, the literature has rendered the direction of the flow irrelevant: a US expatriate in Germany is presumed to face the same hurd...

  20. Adjusting to Retirement: Considerations for Counselors.

    Science.gov (United States)

    LaBauve, Bill J.; Robinson, Chester R.

    1999-01-01

    Examines retirement, while focusing on issues older adults face in adjusting to retirement, and suggests implications for counseling people who are making this transition. Discusses adjustment to retirement in terms of role, disengagement, activity, continuity, crisis, and compromise/negotiation theories. (Author/MKA)

  1. Ergonomically Adjustable School Furniture for Male Students

    Science.gov (United States)

    Al-Saleh, Khalid S.; Ramadan, Mohamed Z.; Al-Ashaikh, Riyad A.

    2013-01-01

    The need for adjustability in school furniture, in order to accommodate the variation in anthropometric measures of different genders, cultures and ages is becoming increasingly important. Four chair-table combinations, different in dimensions, with adjustable chair seating heights and table heights were designed, manufactured and distributed to…

  2. 7 CFR 1744.64 - Budget adjustment.

    Science.gov (United States)

    2010-01-01

    ... another source, requests a deficiency loan, or scales back the project. (b) RUS may make a budget... AGRICULTURE POST-LOAN POLICIES AND PROCEDURES COMMON TO GUARANTEED AND INSURED TELEPHONE LOANS Advance and... description of how the adjustment will affect loan purposes. RUS will not approve a budget adjustment...

  3. Macroeconomic shocks and firms' labor adjustment

    DEFF Research Database (Denmark)

    Eriksson, Tor

    2013-01-01

    , but a brief discussion of cross-country differences and similarities in firmlevel labor adjustment is also provided. For Denmark, remarkable long-term stability in firms’ labor adjustment technologies is observed and the cross-country comparisons reveal striking similarities between countries with very...... diverse labor market institutions....

  4. Adjustment of the Internal Tax Scale

    CERN Multimedia

    2013-01-01

    In application of Article R V 2.03 of the Staff Regulations, the internal tax scale has been adjusted with effect on 1 January 2012. The new scale may be consulted via the CERN Admin e-guide.  The notification of internal annual tax certificate for the financial year 2012 takes into account this adjustment. HR Department (Tel. 73907)

  5. Research on Adjust Time of Premium

    Institute of Scientific and Technical Information of China (English)

    2000-01-01

    By considering economic strength and economic profit of insurance company, this paper presents a concept-contact point, and gives premium expectation adjust time model which provides more practical significance for insurance company to make rational adjustment of premium. Finally, an illustration is given to show their application.

  6. Divorcing Parents: Guidelines for Promoting Children's Adjustment.

    Science.gov (United States)

    Freeman, Kurt A.; Adams, Christina D; Drabman, Ronald S.

    1998-01-01

    There are measures that parents can take to help their children through the often distressing process of parental divorce. Describes the empirical literature regarding issues and factors relevant to children's adjustment to divorce. Provides practical guidelines and suggestions likely to help parents enhance their children's adjustment.…

  7. Religiousity, Spirituality and Adolescents' Self-Adjustment

    Science.gov (United States)

    Japar, Muhammad; Purwati

    2014-01-01

    Religiuosity, spirituality, and adolescents' self-adjustment. The objective of this study is to test the correlation among religiosity, spirituality and adolescents' self-adjustment. A quantitative approach was employed in this study. Data were collected from 476 junior high schools students of 13 State Junior High Schools and one Junior High…

  8. The choice of a 'Best' assisted history matching algorithm

    NARCIS (Netherlands)

    Hanea, R.G.; Przybysz-Jarnut, J.K.; Krymskaya, M.V.; Heemink, A.W.; Jansen, J.D.

    2010-01-01

    Computer-assisted history matching is the act of systematicalty adjusting a ‘prior’ reservoir model using measured data until its simulated production response closely reproduces the past behavior of the reservoir. Thereafler, the updated, ‘posterior’, model is expected to predict future reservoir b

  9. Adjusting the inner-structure of polypyrrole nanoparticles through microemulsion polymerization

    Energy Technology Data Exchange (ETDEWEB)

    Liu Yang [Department of Chemistry, Northeast Normal University, Changchun, Jilin 130024 (China); Chu Ying [Department of Chemistry, Northeast Normal University, Changchun, Jilin 130024 (China)]. E-mail: chuying@nenu.edu.cn; Yang Likun [Department of Chemistry, Northeast Normal University, Changchun, Jilin 130024 (China)

    2006-08-01

    The inner-structure of polypyrrole (PPy) nanoparticles can be straightly adjusted by a simple alcohol-assisted microemulsion polymerization. The characteristic peaks of PPy in infrared spectroscopy (IR) confirm the formation of PPy. The morphology of PPy nanoparticles was characterized by transmission electron microscopy (TEM) and scanning electron microscopy (SEM). UV-vis and Raman spectra exhibit that the conjugation and order of PPy chains were improved directly in the presence of alcohols and adjusted by the alkyl unit of alcohols. These changes in the molecular structure lead to the improvement in the electrical conductivity of as-prepared PPy nanoparticles obviously.

  10. Maintained inspiratory activity during proportional assist ventilation in surfactant-depleted cats early after surfactant instillation: phrenic nerve and pulmonary stretch receptor activity

    Directory of Open Access Journals (Sweden)

    Schaller Peter

    2006-03-01

    Full Text Available Abstract Background Inspiratory activity is a prerequisite for successful application of patient triggered ventilation such as proportional assist ventilation (PAV. It has recently been reported that surfactant instillation increases the activity of slowly adapting pulmonary stretch receptors (PSRs followed by a shorter inspiratory time (Sindelar et al, J Appl Physiol, 2005 [Epub ahead of print]. Changes in lung mechanics, as observed in preterm infants with respiratory distress syndrome and after surfactant treatment, might therefore influence the inspiratory activity when applying PAV early after surfactant treatment. Objective To investigate the regulation of breathing and ventilatory response in surfactant-depleted young cats during PAV and during continuous positive airway pressure (CPAP early after surfactant instillation in relation to phrenic nerve activity (PNA and the activity of PSRs. Methods Seven anesthetized, endotracheally intubated young cats were exposed to periods of CPAP and PAV with the same end-expiratory pressure (0.2–0.5 kPa before and after lung lavage and after surfactant instillation. PAV was set to compensate for 75% of the lung elastic recoil. Results Tidal volume and respiratory rate were higher with lower PaCO2 and higher PaO2 during PAV than during CPAP both before and after surfactant instillation (p Conclusion PSR activity and the control of breathing are maintained during PAV in surfactant-depleted cats early after surfactant instillation, with a higher ventilatory response and a lower breathing effort than during CPAP.

  11. Role of Osmotic Adjustment in Plant Productivity

    Energy Technology Data Exchange (ETDEWEB)

    Gebre, G.M.

    2001-01-11

    Successful implementation of short rotation woody crops requires that the selected species and clones be productive, drought tolerant, and pest resistant. Since water is one of the major limiting factors in poplar (Populus sp.) growth, there is little debate for the need of drought tolerant clones, except on the wettest of sites (e.g., lower Columbia River delta). Whether drought tolerance is compatible with productivity remains a debatable issue. Among the many mechanisms of drought tolerance, dehydration postponement involves the maintenance of high leaf water potential due to, for example, an adequate root system. This trait is compatible with productivity, but requires available soil moisture. When the plant leaf water potential and soil water content decline, the plant must be able to survive drought through dehydration tolerance mechanisms, such as low osmotic potential or osmotic adjustment. Osmotic adjustment and low osmotic potential are considered compatible with growth and yield because they aid in the maintenance of leaf turgor. However, it has been shown that turgor alone does not regulate cell expansion or stomatal conductance and, therefore, the role of osmotic adjustment is debated. Despite this finding, osmotic adjustment has been correlated with grain yield in agronomic crop species, and gene markers responsible for osmotic adjustment are being investigated to improve drought tolerance in productive progenies. Although osmotic adjustment and low osmotic potentials have been investigated in several forest tree species, few studies have investigated the relationship between osmotic adjustment and growth. Most of these studies have been limited to greenhouse or container-grown plants. Osmotic adjustment and rapid growth have been specifically associated in Populus and black spruce (Picea mariuna (Mill.) B.S.P.) progenies. We tested whether these relationships held under field conditions using several poplar clones. In a study of two hybrid poplar

  12. Adjustment and mental health problem in prisoners

    Directory of Open Access Journals (Sweden)

    Sudhinta Sinha

    2010-01-01

    Full Text Available Background : "Crime" is increasing day by day in our society not only in India but also all over the world. In turn, the number of prisoners is also increasing at the same rate. They remain imprisoned for a long duration or in some cases for the whole life. Living in a prison for long time becomes difficult for all inmates. So they often face adjustment and mental health problems. Recent findings suggest that mental illness rate in prison is three times higher than in the general population. Objective: The aim of the present study was to investigate the adjustment and the mental health problem and its relation in the prisoners. Materials and Methods : In the present study, 37 male prisoners of district jail of Dhanbad District of Jharkhand were selected on purposive sampling basis. Each prisoner was given specially designed Performa - Personal Data Sheet, General Health Questionnaire-12 and Bell Adjustment Inventory. Appropriate statistical tools were used to analyze the data. Results: The results obtained showed poor adjustment in social and emotional areas on the adjustment scale. The study also revealed a significant association between adjustment and mental health problem in the prisoners. Conclusion: The prisoners were found to have poor social and emotional adjustment which has strong association with their mental health.

  13. Assistance Focus: Africa (Brochure)

    Energy Technology Data Exchange (ETDEWEB)

    2014-12-01

    The Clean Energy Solutions Center Ask an Expert service connects governments seeking policy information and advice with one of more than 30 global policy experts who can provide reliable and unbiased quick-response advice and information. The service is available at no cost to government agency representatives from any country and the technical institutes assisting them. This publication presents summaries of assistance provided to African governments, including the benefits of that assistance.

  14. Ventilatory strategy during liver transplantation

    DEFF Research Database (Denmark)

    Sørensen, Henrik; Grocott, Hilary P; Niemann, Mads;

    2014-01-01

    BACKGROUND: As measured by near infrared spectroscopy (NIRS), cerebral oxygenation (ScO2) may be reduced by hyperventilation in the anhepatic phase of liver transplantation surgery (LTx). Conversely, the brain may be subjected to hyperperfusion during reperfusion of the grafted liver. We...... liver, ScO2 increased by 5.5% (3.8-7.3%), EtCO2 by 0.7 kPa (0.5-0.8 kPa), and VE by 0.6 L/min (0.3-0.9 L/min; all P

  15. Couples' patterns of adjustment to colon cancer.

    Science.gov (United States)

    Northouse, L L; Mood, D; Templin, T; Mellon, S; George, T

    2000-01-01

    The objectives for this longitudinal study were to: (a) compare colon cancer patients' and their spouses' appraisal of illness, resources, concurrent stress, and adjustment during the first year following surgery; (b) examine the influence of gender (male vs female) and role (patient vs spouse caregiver) on study variables; (c) assess the degree of correlation between patients' and spouses' adjustments; and (d) identify factors that affect adjustment to the illness. Fifty-six couples were interviewed at one week post diagnosis, and at 60 days and one year post surgery. Based on a cognitive-appraisal model of stress, the Smilkstein Stress Scale was used to measure concurrent stress; the Family APGAR, Social Support Questionnaire, and Dyadic Adjustment Scale were used to measure social resources; the Beck Hopelessness Scale and Mishel Uncertainty in Illness Scales were used to measure appraisal of illness; and the Brief Symptom Inventory and Psychosocial Adjustment to Illness Scale were used to measure psychosocial adjustment. Repeated Measures Analysis of Variance indicated that spouses reported significantly more emotional distress and less social support than patients. Gender differences were found, with women reporting more distress, more role problems, and less marital satisfaction, regardless of whether they were patient or spouse. Both patients and spouses reported decreases in their family functioning and social support, but also decreases in emotional distress over time. Moderately high autocorrelations and modest intercorrelations were found among and between patients' and spouses' adjustment scores over time. The strongest predictors of patients' role adjustment problems were hopelessness and spouses' role problems. The strongest predictors of spouses' role problems were spouses' own baseline role problems and level of marital satisfaction. Interventions need to start early in the course of illness, be family-focused, and identify the couples at risk of

  16. Structural Adjustment of Oasis Agriculture in Xinjiang

    Institute of Scientific and Technical Information of China (English)

    Lei Jun; Zhang Xiaolei

    2005-01-01

    Xinjiang's oasis agriculture has made enormous strides over past decades. Structural adjustment of oasis agriculture sector has promoted production diversification. Xinjiang's oasis agriculture sector is entering a new era. The era means more adjustments in oasis agricultural and rural economic structure so as to realize the sustainable development of agriculture. By summing and analyzing the main problems in Xinjinag's oasis agricultural structure,such as raising farmer's income, industry structure within agriculture, rural urbanization, pressure coming from market, agricultural environment degradation,puts forward the thinking, director and countermeasures to adjust oasis agricultural structure.

  17. A note on how to iterate adjustment

    Energy Technology Data Exchange (ETDEWEB)

    Wagschal, Jehudah J.; Yeivin, Yehuda [Hebrew University of Jerusalem, Racah Institute of Physics, Jerusalem (Israel)

    2002-08-01

    We study the elementary problem of adjusting a given parameter library by one measured response so that calculating the response with the adjusted library reproduces the measured value. We formulate the problem of the least-squares adjustment for non-linear responses, and offer a reasoned iteration scheme to solve it. A numerical example illustrates the success of the proposed procedure. Our scheme is identical to that suggested by Perey, and thus adds insight, offers justification, and also serves as a formal proof of the latter. (author)

  18. Robot-Assisted Navigation versus Computer-Assisted Navigation in Primary Total Knee Arthroplasty: Efficiency and Accuracy.

    Science.gov (United States)

    Clark, Tanner C; Schmidt, Frank H

    2013-01-01

    Background. Since the introduction of robot-assisted navigation in primary total knee arthroplasty (TKA), there has been little research conducted examining the efficiency and accuracy of the system compared to computer-assisted navigation systems. Objective. To compare the efficiency and accuracy of Praxim robot-assisted navigation (RAN) and Stryker computer-assisted navigation (CAN) in primary TKA. Methods. This was a retrospective study consisting of 52 patients who underwent primary TKA utilizing RAN and 29 patients utilizing CAN. The primary outcome measure was navigation time. Secondary outcome measures included intraoperative final mechanical axis alignment, intraoperative robot-assisted bone cut accuracy, tourniquet time, and hospitalization length. Results. RAN navigation times were, on average, 9.0 minutes shorter compared to CAN after adjustment. The average absolute intraoperative malalignment was 0.5° less in the RAN procedures compared to the CAN procedures after adjustment. Patients in the RAN group tended to be discharged 0.6 days earlier compared to patients in the CAN group after adjustment. Conclusions. Among patients undergoing TKA, there was decreased navigation time, decreased final malalignment, and decreased hospitalization length associated with the use of RAN when compared to CAN independent of age, BMI, and pre-replacement alignment.

  19. Couples' adjustment to breast cancer and benign breast disease: a longitudinal analysis.

    Science.gov (United States)

    Northouse, L L; Templin, T; Mood, D; Oberst, M

    1998-01-01

    A comprehensive comparison of couples' adjustment to benign (n = 73 couples) and malignant breast disease (n = 58 couples) at the time of diagnosis and at two follow-up assessments at 60 days and 1 year is reported. Specific objectives were to: (a) compare the concurrent stress, resources, appraisal, and patterns of adjustment of couples in the benign and malignant groups; (b) compare the psychosocial responses of patients versus spouses; and (c) determine the amount of correspondence in levels of adjustment reported by patients and their husbands over time. Multiple instruments with reported reliability and validity were used to measure study variables: Smilkstein Stress Scale, Dyadic Adjustment Scale, Family APGAR, Social Support Questionnaire, Mishel Uncertainty in Illness Scale, Beck Hopelessness Scale, Brief Symptom Inventory, and Psychosocial Adjustment to Illness Scale. Mixed design analyses of covariance (ANCOVA) were used to assess differences between and among couples and examine changes in study variables over time. Significant differences were found in the resources, appraisal, and patterns of adjustment reported by couples in the benign and malignant groups. Couples facing breast cancer reported greater decreases in their marital and family functioning, more uncertain appraisals, and more adjustment problems associated with the illness. In addition, there was a high degree of correspondence between the levels of adjustment reported by women with breast cancer and their husbands over time. Couples who reported high distress or a high number of role problems at diagnosis were likely to remain highly distressed at 60 days and 1 year. Study findings underscore the importance of assisting couples, not just patients, to manage the adjustment difficulties associated with breast cancer.

  20. Dose Adjustment for Normal Eating: A Role for the Expert Patient?

    Directory of Open Access Journals (Sweden)

    Harold David McIntyre

    2014-04-01

    Full Text Available The Dose Adjustment for Normal Eating (DAFNE programme of intensive insulin therapy for type 1 diabetes provides a structured educational intervention to improve glycemic control, reduce hypoglycemia and improve quality of life. Enhancement of self-management skills is a key element of DAFNE and patients acquire detailed skills in insulin dose adjustment. Following DAFNE training, patients report improved confidence in their ability to manage their own insulin dosing, but generally still seek and require the assistance of health professionals when making substantial changes to their insulin regimens. Some DAFNE trained patients may be able to assist their peers in aspects of diabetes management within a group environment, but widespread introduction of the expert patient/peer educator role in the self-management of type 1 diabetes, in particular related to insulin dose management, would require formal and detailed evaluation, preferably in randomized controlled clinical trials, before being introduced into routine clinical practice.

  1. Assisted suicide and euthanasia.

    Science.gov (United States)

    van der Heide, Agnes

    2013-01-01

    Several countries have adopted laws that regulate physician assistance in dying. Such assistance may consist of providing a patient with a prescription of lethal medication that is self-administered by the patient, which is usually referred to as (physician) assistance in suicide, or of administering lethal medication to a patient, which is referred to as euthanasia. The main aim of regulating physician assistance in dying is to bring these practices into the open and to provide physicians with legal certainty. A key condition in all jurisdictions that have regulated either assistance in suicide or euthanasia is that physicians are only allowed to engage in these acts upon the explicit and voluntary request of the patient. All systems that allow physician assistance in dying have also in some way included the notion that physician assistance in dying is only accepted when it is the only means to address severe suffering from an incurable medical condition. Arguments against the legal regulation of physician assistance in dying include principled arguments, such as the wrongness of hastening death, and arguments that emphasize the negative consequences of allowing physician assistance in dying, such as a devaluation of the lives of older people, or people with chronic disease or disabilities. Opinion polls show that some form of accepting and regulating euthanasia and physician assistance in suicide is increasingly supported by the general population in most western countries. Studies in countries where physician assistance in dying is regulated suggest that practices have remained rather stable in most jurisdictions and that physicians adhere to the legal criteria in the vast majority of cases.

  2. Annual adjustments to 2016 financial benefits

    CERN Multimedia

    HR Department

    2016-01-01

    In accordance with recommendations made by the Finance Committee and decisions taken by the Council in December 2015, no adjustments have been made to basic salaries and stipends, subsistence allowances or family benefits as at 1 January 2016.  

  3. Annual adjustments to 2014 financial benefits

    CERN Multimedia

    2013-01-01

    In accordance with recommendations made by the Finance Committee and decisions taken by Council in December 2013, no adjustments have been made to basic salaries and stipends, subsistence allowances or family benefits as at 1 January 2014. HR Department

  4. Annual adjustments to 2015 financial benefits

    CERN Multimedia

    HR Department

    2015-01-01

    In accordance with recommendations made by the Finance Committee and decisions taken by Council in December 2014, no adjustments have been made to basic salaries and stipends, subsistence allowances or family benefits as at 1 January 2015.

  5. Speed of adjustment: Evidence from Borsa Istanbul

    Directory of Open Access Journals (Sweden)

    Emrah Arioglu

    2014-06-01

    Full Text Available In this study, we investigate the speed of adjustment for leverage ratios of firms listed on Borsa Istanbul, in order to investigate the prediction of the trade-off theory, regarding capital structure rebalancing. For this purpose, we estimate the speed of adjustment by using Generalized Method of Moments system estimation technique. The results of this estimation suggest the speed of adjustment as approximately 29%. This significant speed of adjustment is consistent with the prediction of trade-off theory, which suggests that firms follow target capital structures and when the firms' leverage ratios deviate from these targets; they make financial decisions with the goal of closing the gap between the previous year's leverage and target leverage of the current period.

  6. Determinants of intercultural adjustment among expatriate spouses

    NARCIS (Netherlands)

    Ali, Anees; Van der Zee, K.I.; Sanders, G

    2003-01-01

    The adaptation of expatriate families to a host country seems crucial to successful fulfilment of international business assignments. The present study focused on personality, family characteristics and characteristics of expatriates' work life as determinants of the intercultural adjustment of expa

  7. Risk-adjusted monitoring of survival times

    Energy Technology Data Exchange (ETDEWEB)

    Sego, Landon H.; Reynolds, Marion R.; Woodall, William H.

    2009-02-26

    We consider the monitoring of clinical outcomes, where each patient has a di®erent risk of death prior to undergoing a health care procedure.We propose a risk-adjusted survival time CUSUM chart (RAST CUSUM) for monitoring clinical outcomes where the primary endpoint is a continuous, time-to-event variable that may be right censored. Risk adjustment is accomplished using accelerated failure time regression models. We compare the average run length performance of the RAST CUSUM chart to the risk-adjusted Bernoulli CUSUM chart, using data from cardiac surgeries to motivate the details of the comparison. The comparisons show that the RAST CUSUM chart is more efficient at detecting a sudden decrease in the odds of death than the risk-adjusted Bernoulli CUSUM chart, especially when the fraction of censored observations is not too high. We also discuss the implementation of a prospective monitoring scheme using the RAST CUSUM chart.

  8. 76 FR 67500 - Postal Service Price Adjustment

    Science.gov (United States)

    2011-11-01

    ... Adjustment Notice states that the overall average for Special Services is a result of large price reductions...; Address Management Services; Caller Service; Change-of-Address Credit Card Authentication; Confirm... Periodicals, Nonprofit and Classroom Periodicals, Science of Agriculture Periodicals advertising...

  9. Continuity Adjustment for Control Charts for Attributes

    Institute of Scientific and Technical Information of China (English)

    L.K. Chan; T.K. Mak; B. Tao

    2003-01-01

    A unified approach is proposed for making a continuity adjustment on some control charts for attributes, e.g., np-chart and c-chart, through adding a uniform (0, 1) random observation to the conventional sample statistic (e.g., npi and ci). The adjusted sample statistic then has a continuous distribution. Consequently, given any Type I risk α (the probability that the sample statistic is on or beyond the control limits),control charts achieving the exact value of α can be readily constructed. Guidelines are given for when to use the continuity adjustment control chart, the conventional Shewhart control chart (with ±3 standard deviations control limits), and the control chart based on the exact distribution of the sample statistic before adjustment.

  10. Annual adjustments to 2013 financial benefits

    CERN Multimedia

    2013-01-01

    In accordance with recommendations made by the Finance Committee and decisions taken by Council in December 2012, no adjustments have been made to basic salaries and stipends, subsistence allowances or family benefits as at 1 January 2013. HR Department

  11. Industrial Forecasts after Export Rebates Adjustment

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    @@ On June 19, 2007, the Circular of the Ministry of Finance and the State Administration of Taxation concerning Lowering the Export Rebate Rates for Some Commodities was published, which finally proved the early rumor of tax rebate adjustment to be true.According to the Circular, the export rebate rates for some commodities have been adjusted upon approval of the State Council and the new rates have become in force since July 1, 2007.

  12. Price Changes, Resource Adjustments and Rational Expectations

    DEFF Research Database (Denmark)

    Hoffmann, Kira

    This study investigates the relationship between the accuracy of managerial demand expectations, resource adjustment decisions and selling price changes. In line with rational expectation theory, it is argued that managers adjust resources and selling prices differently in response to expected...... that cost elasticity is higher when a demand decrease is expected among companies with similar exposure to demand uncertainty. Overall, this implies that managerial competences in predicting future demand significantly determines firms’ profitability; especially when demand uncertainty is high...

  13. Medical Assisting Program Guide.

    Science.gov (United States)

    Georgia Univ., Athens. Dept. of Vocational Education.

    This guide presents the standard curriculum for technical institutes in Georgia. The curriculum addresses the minimum competencies for a medical assisting program. The program guide is designed to relate primarily to the development of those skills needed by individuals in the medical assisting field, such as medical law and ethics, typing,…

  14. The effect of accuracy motivation on anchoring and adjustment: do people adjust from provided anchors?

    Science.gov (United States)

    Simmons, Joseph P; LeBoeuf, Robyn A; Nelson, Leif D

    2010-12-01

    Increasing accuracy motivation (e.g., by providing monetary incentives for accuracy) often fails to increase adjustment away from provided anchors, a result that has led researchers to conclude that people do not effortfully adjust away from such anchors. We challenge this conclusion. First, we show that people are typically uncertain about which way to adjust from provided anchors and that this uncertainty often causes people to believe that they have initially adjusted too far away from such anchors (Studies 1a and 1b). Then, we show that although accuracy motivation fails to increase the gap between anchors and final estimates when people are uncertain about the direction of adjustment, accuracy motivation does increase anchor-estimate gaps when people are certain about the direction of adjustment, and that this is true regardless of whether the anchors are provided or self-generated (Studies 2, 3a, 3b, and 5). These results suggest that people do effortfully adjust away from provided anchors but that uncertainty about the direction of adjustment makes that adjustment harder to detect than previously assumed. This conclusion has important theoretical implications, suggesting that currently emphasized distinctions between anchor types (self-generated vs. provided) are not fundamental and that ostensibly competing theories of anchoring (selective accessibility and anchoring-and-adjustment) are complementary.

  15. Adjustable versus non-adjustable suture techniques for concomitant horizontal strabismus: a comparative study

    Directory of Open Access Journals (Sweden)

    Galton C. Vasconcelos

    2015-12-01

    Full Text Available ABSTRACT Purpose: To compare the surgical results of adjustable and non-adjustable horizontal strabismus surgery for concomitant horizontal strabismus. Methods: The charts of 231 patients, who underwent horizontal strabismus surgery, selected using probabilistic sampling, were retrospectively reviewed. Patients were divided into two groups according to the surgical technique used and strabismus type. The adjustable suture technique was used for 107 patients (Group 1, and non-adjustable or conventional surgery was performed in the remaining 124 patients (Group 2. Patients with esotropia (ET or exotropia (XT of 5 PD, syndromes, restrictive or paretic strabismus, reoperations, botulinum toxin injection, and patients postoperatively followed up for 50% was present in all subgroups. Significant differences between strabismus groups submitted to adjustable technique and non-adjustable on postoperative day 1 were observed (p=0.00 for ET and p=0.01 for XT and at the last visit for the XT group with a follow-up of at least 1 year (p=0.05. Conclusion: The adjustable suture technique produced a higher success rate than non-adjustable strabismus surgery for both ET and XT groups on postoperative day 1. For XT patients, the adjustable suture technique appears to produce better surgical results than non-adjustable surgery, when the surgical goal is long-lasting maintenance of a small hypercorrection.

  16. 24 CFR 882.410 - Rent adjustments.

    Science.gov (United States)

    2010-04-01

    ... URBAN DEVELOPMENT (SECTION 8 HOUSING ASSISTANCE PROGRAMS, SECTION 202 DIRECT LOAN PROGRAM, SECTION 202 SUPPORTIVE HOUSING FOR THE ELDERLY PROGRAM AND SECTION 811 SUPPORTIVE HOUSING FOR PERSONS WITH DISABILITIES PROGRAM) SECTION 8 MODERATE REHABILITATION PROGRAMS Special Procedures for Moderate...

  17. 78 FR 57129 - Notice of Petitions by Firms for Determination of Eligibility To Apply for Trade Adjustment...

    Science.gov (United States)

    2013-09-17

    ... Eligibility To Apply for Trade Adjustment Assistance Date accepted Firm name Firm address for Product(s) investigation York Imperial Plastics, Inc 718 Country Road, York, 9/9/2013 The firm manufactures plastic PA.... Unlimited Designs, Inc 780 North Warm Springs 9/10/2013 The firm manufactures Road (700 West),...

  18. 77 FR 74643 - Notice of Petitions by Firms for Determination of Eligibility To Apply for Trade Adjustment...

    Science.gov (United States)

    2012-12-17

    ... for Trade Adjustment Assistance AGENCY: Economic Development Administration, Department of Commerce.... Beecher and Myers Co., Inc 3753 Carlisle Road, Dover, 10/26/2012 Manufacturer of custom-cut PA 17315. wooden materials as well as provides edge banding, CNC routing, and light assembly services to...

  19. Characteristics of ventilatory response during exercise test in pubertal boys and girls with different BMI%不同体质指数少年运动负荷试验中气体代谢特点分析

    Institute of Scientific and Technical Information of China (English)

    李红娟; 李新; 王艳; 高宇; 张雪婷

    2012-01-01

    目的 探讨不同体质指数(BMI)少年在递增负荷运动试验中气体代谢特点及性别差异.方法 选取不同BMI水平的13~14岁初中学生75名(男40名,女35名)进行递增负荷运动试验,分析极量负荷和无氧阈负荷下,各BMI组少年气体代谢的特点.数据采用SPSS 16.0进行Shapiro-Wilk正态分布检验,单因素方差分析等,P <0.05为差异有统计学意义.结果 校正体重后,与正常BMI少年相比,极量运动时,肥胖组男生摄氧量{[(23.36±5.28)vs (35.856±6.92)][ml/ (min· kg)],F=15.571,P<0.01}和每分种通气量{[(519±144)vs(807±225)][ml/ (min· kg)],F=8.440,P<0.01}均显著下降,女生摄氧量{[(26.50±4.37)vs(30.21±3.19)][ml/ (min· kg)],F=7.169,P<0.05}和每分种通气量{[(646±136)vs(787±141)] [ml/ (min· kg)],F=6.649,P<0.05}均显著下降,肥胖组男生潮气量显著降低{[(14.83±3.61)vs(21.83±4.53)] ml/kg,F=11.122,P<0.01};无氧阈时刻,肥胖组男生相对摄氧量{[(12.24±2.56) vs (17.92±4.07)][ml/(min· kg),F=9.557,P<0.01}和CO2呼出量{[(9.64±2.62)vs(13.81±3.40)] ml/kg,F=6.358,P<0.01}均显著下降,女生各组间差异无统计学意义;不同BMI组通气效率男女生差异均无统计学意义.结论 在青春发育期,超重与肥胖影响了青少年的最大有氧能力和肺通气功能.超重和肥胖少年无氧阈时刻摄氧量百分比仍处于正常范围,通气效率未受影响,表明超重与肥胖少年在无氧阈时刻肺通气功能的代偿调节仍然可以满足其代谢需求.%Objective To understand the characteristics of ventilatory response during graded exercise test in boys and girls with different BMI. Methods 75 healthy adolescents (40 boys and 45 girls) aged 13-14 years were recruited to undergo the progressive maximal exercise test with ergometer, the ventilatiory response of boys and girls of different body mass index (BMI) groups at the maximal load and anaerobic threshold (AT) load were analyzed. The statistical

  20. FEMA Hazard Mitigation Assistance Flood Mitigation Assistance (FMA) Data

    Data.gov (United States)

    Department of Homeland Security — This dataset contains closed and obligated projects funded under the following Hazard Mitigation Assistance (HMA) grant programs: Flood Mitigation Assistance (FMA)....

  1. Respuesta ventilatoria al ejercicio post-entrenamiento de miembros superiores en la enfermedad pulmonar obstructiva crónica Ventilatory response to upper limb exercise after training in COPD

    Directory of Open Access Journals (Sweden)

    Martín Sívori

    2013-02-01

    Full Text Available Está poco estudiada la modificación de la respuesta ventilatoria al ejercicio de miembros superiores (MS post-entrenamiento en la EPOC. Se realizó un estudio prospectivo, aleatorio y controlado en pacientes con EPOC, entrenando un grupo los miembros inferiores (GC y otro adicionalmente los MS (GM. Se comparó la respuesta ventilatoria al ejercicio de MS pre y post-entrenamiento. Se estudiaron 43 pacientes, 84% varones, estadio GOLD II (moderado 6 (14%, GOLD III (grave 15 (35% y GOLD IV (muy grave 22 (51%. Veintiocho pacientes completaron el estudio. Post-entrenamiento: se observó en el grupo GM (N = 14 incrementos del V T isotiempo (p There are scarce studies evaluating the modification of ventilatory response to upper limb exercise (ULE post-training in COPD patients. A prospective, randomized, controlled study was performed comparing two groups: training lower limbs (LL, vs. LL plus upper limb training (UL, in relation to their pre and post-training ventilatory response to ULE. A total of 43 COPD patients were included; 84% male, 6 (14% GOLD moderate stage (II, 15 (35% severe stage (III, and 22 (51% very severe (IV; 28 patients completed the study. After ULE, in UL group (N = 14 a training increased isotime VT (p < 0.0001 was observed, as well as an increase in the inspiratory capacity isotime percentage (IC, 8.8%, p = 0.001, in the Ti isotime (29.3%, p = 0.022 and in the Ti/Tot isotime (37.4%, p = 0.0004. Also, Te isotime was reduced (26%, p = 0.009 and IC isotime was increased (p = 0.01 after ULE. In LL group (N = 14, training increased VT/Ti isotime (66.86%, p = 0.0005 after ULE. Also, after ULE a decrease in Ti isotime (27.9%, p = 0.015 and in Ti/Tot isotime (22.74%, p = 0.00016 were observed. A moderate correlation was observed between Δ respiratory rate and ΔIC after ULE, only for post-training in UL group (r = -0.53 , p < 0.001. Comparing both groups in relation to their responses to ULE, only in the UL group was a reduction

  2. Mechanical insufflation-exsufflation. Comparison of peak expiratory flows with manually assisted and unassisted coughing techniques.

    Science.gov (United States)

    Bach, J R

    1993-11-01

    Pulmonary complications are major causes of morbidity and mortality for patients with severe expiratory muscle weakness. The purpose of this study was to compare peak cough expiratory flows (PCEFs) during unassisted and assisted coughing and review the long-term use of mechanical insufflation-exsufflation (MI-E) for 46 neuromuscular ventilator users. These individuals used noninvasive methods of ventilatory support for a mean of 21.1 h/d for 17.3 +/- 15.5 years. They relied on manually assisted coughing and/or MI-E during periods of productive airway secretion. They reported a mean of 0.7 +/- 1.2 cases of pneumonia and other serious pulmonary complications and 2.8 +/- 5.6 hospitalizations during the 16.4-year period and no complications of MI-E. A sample of 21 of these patients with a mean forced vital capacity of 490 +/- 370 ml had a mean maximum insufflation capacity (MIC) achieved by a combination of air stacking of ventilator insufflations and glossopharyngeal breathing of 1,670 +/- 540 ml. The PCEFs for this sample were: following an unassisted inspiration, 1.81 +/- 1.03 L/s; following a MIC maneuver, 3.37 +/- 1.07 L/s; with manual assistance by abdominal compression following a MIC maneuver, 4.27 +/- 1.29 L/s; and with MI-E, 7.47 +/- 1.02 L/s. Each PCEF was significantly greater than the preceding, respectively (p < 0.01). We conclude that manually assisted coughing and MI-E are effective and safe methods for facilitating airway secretion clearance for neuromuscular ventilator users who would otherwise be managed by endotracheal suctioning. Severely decreased MIC, but not necessarily vital capacity, is an indication for tracheostomy.

  3. Energetics of geostrophic adjustment in rotating flow

    Science.gov (United States)

    Juan, Fang; Rongsheng, Wu

    2002-09-01

    Energetics of geostrophic adjustment in rotating flow is examined in detail with a linear shallow water model. The initial unbalanced flow considered first falls tinder two classes. The first is similar to that adopted by Gill and is here referred to as a mass imbalance model, for the flow is initially motionless but with a sea surface displacement. The other is the same as that considered by Rossby and is referred to as a momentum imbalance model since there is only a velocity perturbation in the initial field. The significant feature of the energetics of geostrophic adjustment for the above two extreme models is that although the energy conversion ratio has a large case-to-case variability for different initial conditions, its value is bounded below by 0 and above by 1 / 2. Based on the discussion of the above extreme models, the energetics of adjustment for an arbitrary initial condition is investigated. It is found that the characteristics of the energetics of geostrophic adjustment mentioned above are also applicable to adjustment of the general unbalanced flow under the condition that the energy conversion ratio is redefined as the conversion ratio between the change of kinetic energy and potential energy of the deviational fields.

  4. Robotic assisted laparoscopic colectomy.

    LENUS (Irish Health Repository)

    Pandalai, S

    2010-06-01

    Robotic surgery has evolved over the last decade to compensate for limitations in human dexterity. It avoids the need for a trained assistant while decreasing error rates such as perforations. The nature of the robotic assistance varies from voice activated camera control to more elaborate telerobotic systems such as the Zeus and the Da Vinci where the surgeon controls the robotic arms using a console. Herein, we report the first series of robotic assisted colectomies in Ireland using a voice activated camera control system.

  5. COMPLICACIONES DE LA CIRUGÍA CARDÍACA VIDEO-ASISTIDA / Complications of video-assisted heart surgery

    Directory of Open Access Journals (Sweden)

    Fausto L. Rodríguez Salgueiro

    2012-01-01

    Full Text Available ResumenLa cirugía cardiovascular video-asistida incluye procedimientos extremadamente complejos, como la revascularización miocárdica y las sustituciones valvulares, no exentos de complicaciones fácilmente prevenibles y tratables. En este artículo se discuten las complicaciones de la cirugía cardíaca video-asistida, propias de la posición del paciente: respiratorias, cardiovasculares, quirúrgicas, infecciosas, entre otras. La cirugía cardíaca video-asistida brinda al paciente innumerables ventajas e implica un riesgo potencial de complicaciones evitables. El desarrollo de estos procedimientos es posible gracias a los adelantos tecnológicos y al diseño de nuevas técnicas anestésicas, ventilatorias, farmacológicas y de monitorización.AbstractThe video-assisted cardiac surgery includes extremely complex procedures such as myocardial revascularization and valve replacements, which are not exempt from easily preventable and treatable complications. In this article, the complications of video-assisted cardiac surgery, typical of patient positioning: respiratory, cardiovascular, surgical, infectious, among other complications, are discussed. The video-assisted cardiac surgery offers many advantages to the patient and involves a potential risk of avoidable complications. The development of these procedures is possible thanks to technological advances and the design of new anesthetic, ventilatory, pharmacologic and monitoring techniques.

  6. Society for Assisted Reproductive Technology

    Science.gov (United States)

    The Society for Assisted Reproductive Technology PATIENTS Patient Information What Is SART? Risks of IVF Third Party Reproduction A Patient's Guide to Assisted Reproductive Technology Frequently Asked ...

  7. Adjustments to financial and social benefits

    CERN Multimedia

    HR Department

    2010-01-01

    In accordance with recommendations made by the Finance Committee in November 2009 and decisions taken by the Council in December 2009, certain financial benefits have been adjusted with effect from 1 January 2010. An increase of 1.6% has been applied to the scale of basic salaries and to stipends paid to Fellows (Annexes R A 5 and R A 6 of the Staff Rules and Regulations, respectively). The adjusted amounts are available from the HR Department intranet site or from departmental secretariats. As a result of the evolution of the Geneva consumer price index, no adjustments have been made to the subsistence allowances of Paid Associates and Students (Annex R A 7 of the Staff Rules and Regulations). The following social benefits also remain unchanged: Family, child and infant allowances (Annex R A 3 of the Staff Rules and Regulations). Payment ceilings of education fees (Annex R A 4 of the Staff Rules and Regulations). Tel. 70674 (Classification and Remuneration Service)

  8. Towards Adjustable Autonomy for the Real World

    CERN Document Server

    Pynadath, D V; Tambe, M; 10.1613/jair.1037

    2011-01-01

    Adjustable autonomy refers to entities dynamically varying their own autonomy, transferring decision-making control to other entities (typically agents transferring control to human users) in key situations. Determining whether and when such transfers-of-control should occur is arguably the fundamental research problem in adjustable autonomy. Previous work has investigated various approaches to addressing this problem but has often focused on individual agent-human interactions. Unfortunately, domains requiring collaboration between teams of agents and humans reveal two key shortcomings of these previous approaches. First, these approaches use rigid one-shot transfers of control that can result in unacceptable coordination failures in multiagent settings. Second, they ignore costs (e.g., in terms of time delays or effects on actions) to an agent's team due to such transfers-of-control. To remedy these problems, this article presents a novel approach to adjustable autonomy, based on the notion of a transfer-of...

  9. Psychosocial adjustment to ALS: a longitudinal study

    Directory of Open Access Journals (Sweden)

    Tamara eMatuz

    2015-09-01

    Full Text Available For the current study the Lazarian stress-coping theory and the appendant model of psychosocial adjustment to chronic illness and disabilities (Pakenham 1999 has shaped the foundation for identifying determinants of adjustment to ALS. We aimed to investigate the evolution of psychosocial adjustment to ALS and to determine its long-term predictors. A longitudinal study design with four measurement time points was therefore, used to assess patients’ quality of life, depression, and stress-coping model related aspects, such as illness characteristics, social support, cognitive appraisals and coping strategies during a period of two years. Regression analyses revealed that 55% of the variance of severity of depressive symptoms and 47% of the variance in quality of life at T2 was accounted for by all the T1 predictor variables taken together. On the level of individual contributions, protective buffering and appraisal of own coping potential accounted for a significant percentage in the variance in severity of depressive symptoms, whereas problem management coping strategies explained variance in quality of life scores. Illness characteristics at T2 did not explain any variance of both adjustment outcomes. Overall, the pattern of the longitudinal results indicated stable depressive symptoms and quality of life indices reflecting a successful adjustment to the disease across four measurement time points during a period of about two years.Empirical evidence is provided for the predictive value of social support, cognitive appraisals, and coping strategies, but not illness parameters such as severity and duration for adaptation to ALS. The current study contributes to a better conceptualization of adjustment, allowing us to provide evidence-based support beyond medical and physical intervention for people with ALS.

  10. Financial Assistance Information

    Science.gov (United States)

    ... Other Sites: Genetic and Rare Diseases Information Center Financial Assistance Information The National Institutes of Health (NIH) ... area call 900-638-0742. Top of page Financial Aid for Medical Treatments Information on financial aid ...

  11. [Assisted peritoneal dialysis].

    Science.gov (United States)

    Klarić, Dragan; Prkačin, Ingrid

    2014-04-01

    According to the National Registry of Renal Replacement Therapy (RRT), the incidence of chronic kidney disease (end-stage renal disease) and the need of RRT have declined in the last decade renal. One of the reasons for this tendency certainly is transplantation as the best choice. However, transplant procedure has limitations in elderly patients due to the number of comorbidities. This study was designed as retrospective analysis of outcomes in patients treated with peritoneal dialysis for a period of eleven years. Patients were divided into those who had been assisted or unassisted. Out of 100 patients treated with peritoneal dialysis (PD), 77 completed the treatment, including 26 assisted and 51 unassisted patients. Peritonitis was recorded in 20 assisted and 26 unassisted patients. Peritonitis was more common in unassisted patients, who were more frequently lost from PD. Assisted PD could be a good and safe choice of RRT in this special group of patients.

  12. Superfund Technical Assistance Grants

    Data.gov (United States)

    U.S. Environmental Protection Agency — This asset includes data related to the Superfund Technical Assistance Grant program, including grant number, award amounts, award dates, period of performance,...

  13. Accessibility and assistive products

    Science.gov (United States)

    Rodríguez-Porrero, Cristina

    2009-01-01

    Introduction Accessibility and assistive products and technologies are needed to ensure the rights of persons with disabilities and older persons. Many developments have been implemented in laws, standards, markets and from the consumers perspective, at international, European and national levels. The real issue is that not all the potential users benefit from the use of assistive products or accessible measures. Discussion Innovative methods are needed to allow all potential users to have real advantage of assistive technologies and accessible and design for all facilities. Best practices will be presented and existing gaps and recommendations will be discussed. Cost-benefits aspects will also be presented. Conclusion In order to get advantages from opportunities of globalization, hard work and responsibilities of all stakeholders are needed, so that assistive products and accessibility reach a whole range of situations and environments and contribute to ensure quality of life in a society for all.

  14. 咪唑安定辅助硬膜外阻滞对二氧化碳通气反应的影响%Effects of midazolam on ventilatory response to carbon dioxide when used as sedative during epiduralblockade

    Institute of Scientific and Technical Information of China (English)

    刘存明; 袁冬喜; 张国楼

    2001-01-01

    Objective To investigate the effect of midazolam on ventilatory response to carbondioxide (CO2) when it is used as sedative supplement to epidural blockade(EB). Methods Fifteen ASAⅠ -Ⅱ patients [age (49±7) years , weight (56±13)kg] undergoing upper abdominal surgery were studied. Patients with respiratory disease were excluded. No patient was addicted to smoking, alcohol,received any sedatives or hypotics within one month before surgery. The patients were premedicated with intramuscular phenobarbital 0. 1g and atropine 0.5mg. Epidural catheter was inserted in a cephala direction for 4 cm into epidural space via the tuohy needle at T9.10. 1% lidocaine and 0.2% pontocaine solution was used for epidural block. The level of block was T3.5. When the level of block was fixed, midazolam 0.1mg/kg was given intravenously. Respiratory rate(RR), tidal volume (VT), end-tidal concentration of CO2 (PETCO2) and pulse oxygen saturation (SpO2) were measured before anesthesia (baseline values), before midazolam when the level of block was fixed and 5 min after midazolam. Measurement of ventilatory response to CO2: the patient was asked to breathe with a closed system without a CO2 absorber. PET CO2 increased to 55 mm Hg in 6-10 min. RR, VT and minute ventilation (MV) were measured at PETCO2 40, 45, 50, and 55 mm Hg. The patient then breathed fresh air and PETCO2 returned to normal. 5 min after midazolam the measurment was repeated. The CO2 ventilatory response curve was obtained by plotting MV against the corresponding PET CO2. Results PET CO2, RR and SpO2 did not change significantly after epidural block and midazolam. There was no significant change in VT after epidural block as compared with the baseline value but VT decreased significantly after midazolam (P<0.01).There was no significant change in the slope of CO2 ventilatory response curve before and after midazolam but MV at different PET CO2 decreased significantly 5 min after midazolam. Conclusions Midazolam 0. 1mg

  15. The Kenyan political conflict and children's adjustment.

    Science.gov (United States)

    Kithakye, Mumbe; Morris, Amanda Sheffield; Terranova, Andrew M; Myers, Sonya S

    2010-01-01

    This study examined pre- and postconflict data from 84 children, ages 3-7 years, living in Kibera, Kenya, during the December 2007 political conflict. Results indicate that children's disaster experiences (home destruction, death of a parent, parent and child harm) are associated with adjustment difficulties and that emotion regulation is an important protective factor postdisaster. Specifically, severity of the disaster experience was associated with increased aggression and decreased prosocial behavior. Emotion regulation was associated with less aggression and more prosocial behavior postconflict. Findings are discussed in the context of a developmental, systems-oriented perspective of the impact of disasters on child adjustment.

  16. Adjustable Speed Drives - Future Challenges and Applications

    DEFF Research Database (Denmark)

    Blaabjerg, Frede; Thoegersen, Paul

    2004-01-01

    The main trends within Adjustable Drives in industrial and appliance applications for the next decade are discussed based on the newest developments seen on the market and a few historical trends. Different drive configurations are presented and the general demands to adjustable speed drives...... are specified. Further on power architectures and motor types are discussed in a short term and long-term view. Possible drivers of the future development are identified, and the concept of an ?Electronic Motor? is discussed. A number of applications are presented where variable speed is attractive....

  17. Host country language ability and expatriate adjustment

    DEFF Research Database (Denmark)

    Selmer, Jan; Lauring, Jakob

    2015-01-01

    Research has shown that expatriates’ host country language ability is positively associated with their adjustment. But does the advantage of expatriates’ language ability depend on the difficulty of the host language? To examine this issue, data were collected from expatriates in two European...... countries, one with an easy, relatively simple language and the other with a difficult, highly complex language. Consistent with Goal-Setting Theory, results indicated a relative advantage of expatriates’ language ability in terms of their adjustment in the host country with the difficult language...... as opposed to the host country with an easy language....

  18. Fatores associados ao insucesso no desmame ventilatório de crianças submetidas a cirurgia cardíaca pediátrica Factors associated with failure in ventilatory weaning of children undergone pediatric cardiac surgery

    Directory of Open Access Journals (Sweden)

    Zuleica Menezes Silva

    2008-12-01

    Full Text Available OBJETIVO: Verificar os fatores associados ao insucesso no desmame de crianças submetidas a correção cirúrgica de cardiopatias congênitas. MÉTODOS: Estudo de coorte. A amostra foi composta de 29 crianças. As cardiopatias foram divididas em cianóticas (nove crianças e acianóticas (20 crianças. Foram estudadas crianças de 0 a 5 anos, submetidas a cirurgia cardíaca com permanência em ventilação mecânica invasiva. RESULTADOS: O grupo insucesso apresentou valor menor na SpO2 e valores maiores nos dias de permanência em VMI e na FiO2 quando comparados ao grupo sucesso (POBJECTIVE: To assess factors associated with failure in ventilatory weaning of children undergone surgical correction of congenital heart diseases. METHODS: Cohort study with 29 children. The heart diseases were divided into cyanotic (nine children and acyanotic (20 children. We studied children from 0 to 5 years who underwent heart surgery with invasive mechanical ventilation. RESULTS: The failure group presented smaller value in SpO2 and higher values during days of stay in IMV and FiO2 when compared to the success group (P<0.05. It was observed that 4 children (14% had failed in weaning, being necessary to return the ventilatory prosthesis before 48 hours after extubation. CONCLUSION: The days of IMV, SpO2 and FiO2 were the main factors associated with failed extubation in this group of patients.

  19. Relationship of bronchodilator response with oxygen pulse and ventilatory threshold in children with asthma: the effect of body composition and progressive aerobic activity in an environment with low humidity

    Directory of Open Access Journals (Sweden)

    Samera Puyan majd

    2015-11-01

    Full Text Available Background: Asthma is a leading cause of chronic illness in children, impacting heavily on their daily complications. The purpose of the present study was to relationship bronchodilator response (BDR with oxygen pulse (OP and ventilatory threshold (VT in asthma children with various body compositions during progressive aerobic activities. Material and Methods: 25 obese children (BMI>25 and %fat>30with asthma(10 subjects, and healthy children (15 subjects  and 25 lean children(BMI<20 and %fat<20 with asthma(13 subjects, and healthy children (7 subjects performed an exercise protocol in a constant temperature environment 2 ± 22 ° C and humidity (5 ± 35%. During exercise, the steady-state levels of cardio-respiratory parameters were measured using gas analyzer (K4B2. Results: The results showed that after a progressive aerobic activity, values peak oxygen consumption(vo2peak ​​, bronchodilator(BDR, oxygen pulse(OP and ventilatory threshold(VT  in lean and obese asthmatic children were lower than in healthy lean and obese children. In addition, lean children with asthma had lower VT and higher VO2peak , OP and BDR values​​, as compared obese asthmatic children. Between BDR and VT in lean and obese asthmatic children an inverse relationship between BDR and OP and a direct link to asthma in obese children and obese asthmatic children, there was a negative relationship non-significant. Conclusion: Compared with lean children, asthma, obesity as an additional load will affect lung function and increase the pressure on childhood asthma. Therefore, we can accept that obesity may limit performance of exercise in childhood asthma.

  20. 76 FR 7585 - Notice of Determinations Regarding Eligibility To Apply for Worker Adjustment Assistance

    Science.gov (United States)

    2011-02-10

    .... Support Group; Including Virtual Workers Reporting to this Location. 74,871 International Business.... Storage Management, Teleworkers. 75,087A International Business Smyrna, GA........ December 22, 2009. Machines (IBM), Integrated Technology, Storage Management, Teleworkers. 75,087B International Business...

  1. 77 FR 67406 - Investigations Regarding Eligibility To Apply for Worker Adjustment Assistance

    Science.gov (United States)

    2012-11-09

    ... Richmond & Roanoke, VA 10/15/12 10/12/12 Cross Blue Shield) (Workers). 82080 International Business...- Stop). 82091 T-Shirt International Inc. Culloden, WV 10/18/12 10/16/12 (Company). 82092 General...

  2. 75 FR 70294 - Notice of Determinations Regarding Eligibility To Apply for Worker Adjustment Assistance

    Science.gov (United States)

    2010-11-17

    ...,, Working On-Site at Phoenix Life and Annuity Company. 73,988 International Business Armonk, NY March 1... International Business Lexington, KY......... June 10, 2009. Machines (IBM), Global Tech Serv., Server Systems, IC1, Storage, Backup. 74,316A International Business Cambridge, MA......... June 10, 2009....

  3. 78 FR 54487 - Notice of Determinations Regarding Eligibility To Apply for Worker Adjustment Assistance

    Science.gov (United States)

    2013-09-04

    ... separated; (2) The public agency has acquired from a foreign country services like or directly competitive..., Greyhound Lines. 82,890 YP Southeast Advertising & Tucker, GA Publishing LLC, Customer Service Group, YP LLC...; and (3) One of the following must be satisfied: (A) Imports of articles or services like or...

  4. 76 FR 21408 - Notice of Determinations Regarding Eligibility To Apply for Worker Adjustment Assistance

    Science.gov (United States)

    2011-04-15

    ..... New York, NY November 22, 2009. 75,157 Smethport and Lauri Smethport, PA January 28, 2010. Toys, Patch... Milford, CT December 16, 2009. Limited, Former Workers from Dataviz, Inc. 75,077 Dama Jewelry Johnston,...

  5. 76 FR 13228 - Notice of Determinations Regarding Eligibility To Apply for Worker Adjustment Assistance

    Science.gov (United States)

    2011-03-10

    .... Corporation, Coretechs. 75,058 Electrolux Home Care Webster City, IA...... February 24, 2011. Products, Inc., Electrolux Central Vacuum Systems; AB Electrolux. 75,058A Manpower, Electrolux Home Webster City, IA... Division; Leased Workers Manpower, etc. 75,137 John Crane, Inc Cranston, RI January 24, 2010. 75,147...

  6. 75 FR 49529 - Notice of Determinations Regarding Eligibility To Apply for Worker Adjustment Assistance

    Science.gov (United States)

    2010-08-13

    ... Sedona Staffing. 73,771 Technicolor Video Cassette Detroit, MI March 1, 2009. of Michigan, Thomson, Home......... March 29, 2009. Inc., Automation and Control Solutions Division. 73,870 Amphenol TCS Milpitas, CA... Technology Piscataway, NJ....... May 5, 2009. Enterprise, LLC, Bowne and Company, Inc., Help Desk...

  7. 78 FR 8591 - Notice of Determinations Regarding Eligibility To Apply for Worker Adjustment Assistance

    Science.gov (United States)

    2013-02-06

    ...,111 Carolina Precision Stratford, CT......... October 25, 2011. Plastics, Monroe Staffing. 82,168A... Seneca, SC December 3, 2011. Medical Devices, Kelly Services. 82,220 Netlist, Inc., Test Irvine,...

  8. 77 FR 16070 - Notice of Determinations Regarding Eligibility To Apply for Worker Adjustment Assistance

    Science.gov (United States)

    2012-03-19

    ... date 81,041 Vanguard Pai Monroe, NC July 22, 2011. Lung, LLC. 81,184 C&M Wood Hesperia, CA February 13...., Roanoke, VA February 13, 2010. Sales Fulfillment Division, Kelly Services, Aerotek. 81,211 Solaicx, a... Payment Services (GBPS) inc. Kelly Services. 81,281 Time Warner Coudersport, PA. Entertainment Company,...

  9. 77 FR 17526 - Notice of Determinations Regarding Eligibility To Apply for Worker Adjustment Assistance

    Science.gov (United States)

    2012-03-26

    ... TE Connectivity/Tyco Wilsonville, OR February 10, 2011. Electronics, CIS- Datacomm Division, Kelly...., Manufacturing Division, Monroe Staffing and Adecco. 81,336 Bureau Veritas, Taunton, MA February 14,...

  10. 75 FR 68621 - Notice of Determinations Regarding Eligibility To Apply for Worker Adjustment Assistance

    Science.gov (United States)

    2010-11-08

    ... 16, 2009. Trimline, Accountemps, Kelly, Delta, and Connection. 74,275A Welch Allyn, Inc., Also..., Incorporated, Pleasant Pairie, WI August 30, 2009. Kelly Service. 74,682 Broadview Network Rye Brook, NY........... October 13, 2009. Inc.; Monroe Staffing Services, LLC and Photo Temps. The following certifications...

  11. 75 FR 28298 - Notice of Determinations Regarding Eligibility To Apply for Worker Adjustment Assistance

    Science.gov (United States)

    2010-05-20

    ... Worldwide, Corporate IT Division, Leased Workers from Computer Merchant, LTD, White Plains, NY: September 30... Aerotek Commercial Staffing, Oak Park, MI: November 6, 2008. TA-W-73,028: TRW Automotive, Body Control...: Minnesota Industries, Chisholm, MN. TA-W-71,667: Fort Smith Express, Inc., Fort Smith, AR. TA-W-71,789:...

  12. 76 FR 2718 - Investigations Regarding Certifications of Eligibility To Apply for Worker Adjustment Assistance

    Science.gov (United States)

    2011-01-14

    ............ 12/21/10 12/19/10 (Workers). 75019 Suss Microtec (Workers)..... Waterbury Center, VT.. 12/21/10 12/20/10 75020 John Hancock Life Insurance Milwaukee, WI......... 12/21/10 12/17/10 Company (Company... (Company). 75029 CompX Precision Slides, Inc. Byron Center, MI...... 12/22/10 12/16/10 (Company)....

  13. 78 FR 19531 - Notice of Determinations Regarding Eligibility To Apply for Worker Adjustment Assistance

    Science.gov (United States)

    2013-04-01

    ... Department, Sears Holding Corporation. 82,382 Amdocs, Inc., Amdocs, Ltd, New Haven, CT......... January 21..., Onesource Staffing Solutions, etc. 82,414 Sears Holdings Management Round Rock, TX........ February 4,...

  14. 75 FR 1345 - Solicitation of Applications for the Community Trade Adjustment Assistance Program

    Science.gov (United States)

    2010-01-11

    .... 2371 et seq.) (Trade Act) to help communities respond to the loss of jobs caused by the layoffs at... reverberate throughout an entire community. The closure or downsizing of a key industry, company, or...

  15. 75 FR 38135 - Notice of Determinations Regarding Eligibility To Apply for Worker Adjustment Assistance

    Science.gov (United States)

    2010-07-01

    .... Engineering Services Group. 73,609 Faurecia Emissions Troy, MI February 22, 2009. Control Technologies, Leased..., Mobility Customer, Quality Observation. 73,406 ET Publishing, Inc., Miami, FL January 27, 2009. Accounting..., Quality. 73,435 AT&T Mobility Harrisburg, PA Services, LLC, Consumer Centers Sales, Mobility...

  16. 75 FR 32225 - Investigations Regarding Certifications of Eligibility To Apply for Worker Adjustment Assistance

    Science.gov (United States)

    2010-06-07

    ... Technology Freemont, CA 05/11/10 05/10/10 (Company). ] 74074 Cut Right Wood Products McKenzie, TN 05/11/10 05...). 74076 Feng Sheng Garments, Inc. San Francisco, CA......... 05/12/10 05/05/10 (Workers). 74077 Robb...

  17. 75 FR 47633 - Notice of Determinations Regarding Eligibility To Apply for Worker Adjustment Assistance

    Science.gov (United States)

    2010-08-06

    ... Saxonburg, PA March 26, 2009. Technologies, Inc., Detection & Imaging Systems. 73,952 Genlyte Thomas Group, Fall River, MA......... April 13, 2009. LLC. 74,076 Feng Sheng Garments, San Francisco, CA...... May 5... Technologies Attleboro, MA June 30, 2009. Inc., Customer Service Organization, Leased Workers from...

  18. 75 FR 21359 - Notice of Determinations Regarding Eligibility To Apply for Worker Adjustment Assistance

    Science.gov (United States)

    2010-04-23

    ...: May 16, 2008. TA-W-71,386; LDS Test and Measurement, LLC, HBM LDS Test and Measurement LLC, Bruel and..., Hagerstown, MD: June 8, 2008. TA-W-72,334; International Paper Company, Shreveport Accounting Center... Integrators, Inc., Quality Assurance etc., Leased Workers Strategic Staffing & Volt Accounting, Roseville,...

  19. 75 FR 63147 - Solicitation of Applications for the Public Works, Economic Adjustment Assistance, and Global...

    Science.gov (United States)

    2010-10-14

    ... under EO 12372, applicants may contact their State's Single Point of Contact (SPOC). Names and addresses....whitehouse.gov/omb/grants/spoc.html . Section A.11. of Form ED-900 provides more information and...

  20. 75 FR 54184 - Notice of Determinations Regarding Eligibility to Apply for Worker Adjustment Assistance

    Science.gov (United States)

    2010-09-03

    ... Production Unit; Leased Workers from Mundy. 73,676 Apria Healthcare, Birmingham and Mobile, March 8, 2009. Customer Service AL. Department. 73,676A Apria Healthcare, Little Rock and March 8, 2009. Customer Service.... 73,632 Simclar Interconnect Ozark, MO March 1, 2009. Technologies, Inc., Leased Workers from...

  1. 78 FR 781 - Investigations Regarding Certifications of Eligibility To Apply for Worker Adjustment Assistance

    Science.gov (United States)

    2013-01-04

    ... 12/05/12 12/04/12 (Company). 82206 The Nielsen Company Green Bay, WI 12/05/12 12/04/12 (Company... 12/05/12 12/04/12 82217 IronTiger Logistics, Inc. Garland, TX 12/06/12 12/05/12 (State/One-Stop... Electric Wiring Bowling Green, KY...... 12/07/12 12/06/12 Systems, Inc. (Company). 82224 Evraz...

  2. 75 FR 41528 - Investigations Regarding Certifications of Eligibility To Apply for Worker Adjustment Assistance

    Science.gov (United States)

    2010-07-16

    ...). 74306 HAVI Logistics (Workers)... Livonia, MI 06/28/10 06/25/10 74307 Brockway Mould, Inc. Brockport, PA...)..... Shelton, CT 06/30/10 06/23/10 74327 Wellpoint (Workers)........ Green Bay, WI......... 06/30/10...

  3. 78 FR 66780 - Notice of Determinations Regarding Eligibility To Apply for Worker Adjustment Assistance

    Science.gov (United States)

    2013-11-06

    ... separated; (2) the workers' firm is a Supplier or Downstream Producer to a firm that employed a group of...-- (A) the workers' firm is a supplier and the component parts it supplied to the firm described in.......... August 9, 2012. Medical Systems Division, Kimco Staffing. 82,999 ATOS IT Solutions and Services,...

  4. 78 FR 11227 - Notice of Determinations Regarding Eligibility To Apply for Worker Adjustment Assistance

    Science.gov (United States)

    2013-02-15

    ... separated; (2) The workers' firm is a Supplier or Downstream Producer to a firm that employed a group of...-- (A) The workers' firm is a supplier and the component parts it supplied to the firm described in... Andover, MA November 15, 2011. Co., Inc.. 82,236 CVPH Medical Center.... Plattsburgh, NY...........

  5. 76 FR 16448 - Notice of Determinations Regarding Eligibility To Apply for Worker Adjustment Assistance

    Science.gov (United States)

    2011-03-23

    .... Company, Leased Workers from ETS Staffing. 75,161A Continental Plastics Alpharetta, GA........ January 31... Chesterfield, MI...... January 31, 2010. Company, Chesterfield, Inc., Leased Workers from ETS Staffing. 75,161C Continental Coatings, LLC, China Township, MI.... January 31, 2010. Leased Workers from ETS Staffing....

  6. 75 FR 34173 - Notice of Determinations Regarding Eligibility To Apply for Worker Adjustment Assistance

    Science.gov (United States)

    2010-06-16

    ... 14, 2010 TA-W-73,957: Cessna Aircraft, Columbus Facility, Fabrication and Assembly, Leased Workers...., Butler, PA TA-W-72,697: Lucite International, Inc., Nederland, TX TA-W-73,080: ATK Launch Systems,...

  7. 78 FR 39774 - Notice of Determinations Regarding Eligibility To Apply for Worker Adjustment Assistance

    Science.gov (United States)

    2013-07-02

    .... & Accounting Organization, American Cyber, Ascendo Resources, etc. 82,705 The Boeing Company, BCA-- Auburn, WA.... Infotrieve, Belcan Tech Services, Advantage Human Resourcing, 804 Technolog. 82,790 Ascension...

  8. 77 FR 42335 - Notice of Determinations Regarding Eligibility To Apply for Worker Adjustment Assistance

    Science.gov (United States)

    2012-07-18

    ............ February 27, 2011. & Components Division, Aerotek and Madden Industrial Craftsmen. 81,687 Amerbelle........ July 30, 2011. Communications Test and Measurement Division. 81,722A Lease Workers from Indianapolis, IN..... June 14, 2011. Randstad Sourceright, Working On-Site at JDS Uniphase, Communications Test...

  9. 75 FR 45161 - Notice of Determinations Regarding Eligibility To Apply for Worker Adjustment Assistance

    Science.gov (United States)

    2010-08-02

    ...., Research and Development. 73,210 MetLife Moosic, PA 73,210A MetLife Clarks Summit, PA..... 73,265 HSBC Finance Corporation, Southern Pines, NC.... Consumer & Mortgage Lending, Beneficial Division, HSBC...

  10. 76 FR 14691 - Notice of Determinations Regarding Eligibility To Apply for Worker Adjustment Assistance

    Science.gov (United States)

    2011-03-17

    ... Professionals. 75,153 HSBC Card Services, Inc., Tigard, OR January 27, 2010. Quality Monitoring; Wages Reported under HSBC Technology & Services, Inc. 75,164 Rosemount Analytical, Irvine, CA January 31, 2010....

  11. 78 FR 25481 - Investigations Regarding Eligibility To Apply for Worker Adjustment Assistance

    Science.gov (United States)

    2013-05-01

    .../22/13 82592 JP Morgan Chase--Accounts Los Angeles, CA........ 03/25/13 03/22/13 Reconciliation... Stop). 82602 Wells Fargo Bank (Workers).. Beaverton, OR 03/26/13 03/25/13 82603 GE Ravenna Lamp... Square, PA...... 03/29/13 03/28/13 Stop). 82615 Bank of America/Merrill Jersey City, NJ...........

  12. 77 FR 13352 - Notice of Determinations Regarding Eligibility To Apply for Worker Adjustment Assistance

    Science.gov (United States)

    2012-03-06

    ... 202(b)(1); (B) an affirmative determination of market disruption or threat thereof under section 421(b...., Chicago, IL February 13, 2010. Corporate Resources, Aerotek, Dysis and Tek. 81,254 BT North America... Workforce Carolina. 81,263 Chartis Global Services, Houston, TX February 13, 2010. Inc., Regional...

  13. 76 FR 32229 - Notice of Determinations Regarding Eligibility To Apply for Worker Adjustment Assistance and...

    Science.gov (United States)

    2011-06-03

    ... Act, African Growth and Opportunity Act, or the Caribbean Basin Economic Recovery Act; or 3. there has... loss or business by the workers' firm with the firm (or subdivision) described in paragraph (2... Kissimmee, FL. Concepts, Inc.. I hereby certify that the aforementioned determinations were issued...

  14. 77 FR 71637 - Notice of Determinations Regarding Eligibility To Apply for Worker Adjustment Assistance

    Science.gov (United States)

    2012-12-03

    ........... October 9, 2011. Creative Services Division. 82,071 Covidien LP, Medical Commerce, TX October 10, 2011...,989 Siemens Energy, Inc, Fort Madison, IA...... Renewables (Wind Power) Division. The...

  15. 75 FR 5348 - Investigations Regarding Certifications of Eligibility To Apply for Worker Adjustment Assistance

    Science.gov (United States)

    2010-02-02

    ..., LLC (Comp)........ Mount Union, PA....... 12/28/09 12/22/09 73158 Siemens Medical Solutions, Concord... (State) Oakdale, MN 12/29/09 12/21/09 73163 Siemens Medical Solutions, Malvern, PA 12/29/09 12/15/09...

  16. 76 FR 35478 - Notice of Determinations Regarding Eligibility To Apply for Worker Adjustment Assistance

    Science.gov (United States)

    2011-06-17

    ... of Staffmark & PA Teleworkers. 75,262E Highmark, Human Resources Camp Hill, PA....... February 11... Plymouth, MN........ Cities, Inc, Fansteel Inc.; Leased Workers from American Engineering Testing, etc....

  17. 78 FR 12794 - Notice of Determinations Regarding Eligibility To Apply for Worker Adjustment Assistance

    Science.gov (United States)

    2013-02-25

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF LABOR... Generation Portland, ME January 31, 2012. Network, Inc., NGN--New Generation Network GMBH. 82,412 Buth-Na... San Francisco Shopping San Francisco, CA..... Centre Associates, LP, Kiosk Leasing Department....

  18. 76 FR 54797 - Investigations Regarding Certifications of Eligibility To Apply for Worker Adjustment Assistance...

    Science.gov (United States)

    2011-09-02

    ... petition 80327 Mohawk Laurel Hill, NC....... 08/01/11 07/28/11 (Workers) 80328 Valley Care Health System...) 80346 Graceway Pharmaceuticals, Exton, PA 08/08/11 08/05/11 LLC. (Company) 80347 Pension Systems........ Pottstown, PA......... 08/09/11 08/08/11 (Company) 80352 Penske-Delphi Packard El Paso, TX 08/09/11...

  19. 78 FR 2291 - Investigations Regarding Eligibility To Apply for Worker Adjustment Assistance

    Science.gov (United States)

    2013-01-10

    ... 12/17/12 82271 Nokia, Inc. System Arlington Heights, IL.. 12/18/12 11/15/12 Integration (State/One.... Kalispell, MT 12/18/12 12/13/12 (Workers). 82275 Delphi (Workers) Troy, MI 12/19/12 12/18/12 82276 Peak...

  20. 77 FR 75450 - Investigations Regarding Eligibility To Apply for Worker Adjustment Assistance

    Science.gov (United States)

    2012-12-20

    ... Crane Payment Solutions, Salem, NH 11/20/12 11/19/12 Inc. (Company). 82163 Delphi Connection Systems... Stop). 82169 T-Systems North America Andover, MA 11/23/12 11/21/12 (State/One-Stop). 82170...

  1. 76 FR 24537 - Investigations Regarding Certifications of Eligibility To Apply for Worker Adjustment Assistance...

    Science.gov (United States)

    2011-05-02

    ... Worth, TX........ 04/11/11 04/11/11 Stop). 80103 HIRel Systems LLC (State/ Duluth, MN 04/12/11 04/11/11.... Hickory, NC 04/13/11 04/13/11 (Company). 80106 Delphi (Workers) El Paso, TX 04/14/11 04/05/11 80107...

  2. 76 FR 30978 - Ivestigations Regarding Certifications of Eligibility To Apply for Worker Adjustment Assistance...

    Science.gov (United States)

    2011-05-27

    ... Systems Corporation Sherman Oaks, CA....... 05/10/11 05/06/11 (Company). 80161 Rockford Register Star... (Workers). 80172 Burner Systems International Springfield, TN........ 05/10/11 05/03/11 (State/One-Stop). 80173 Hoquiam Plywood (Company)... Hoquiam, WA 05/11/11 05/09/11 80174 Delphi Corporation (State/...

  3. 75 FR 41524 - Notice of Determinations Regarding Eligibility To Apply for Worker Adjustment Assistance

    Science.gov (United States)

    2010-07-16

    ... International, Phoenix, AZ June 7, 2009. Inc., Aerospace Division, Inbound Logistics Group. 74,250 Charming... Technical Center. 74,261 Kenco Logistic Services, LLC. Evansville, IN I hereby certify that...

  4. 76 FR 30394 - Amended Certification Regarding Eligibility To Apply for Worker Adjustment Assistance

    Science.gov (United States)

    2011-05-25

    ... LLC Lanham, Maryland TA-W-72,251K SUPERVALU, Inc. IT and Finance Departments Including Workers Whose..., Colorado (TA-W-72,251I); SUPERVALU, Inc., IT and Finance Departments, Lanham, Maryland (TA-W-72,251J...., and American Drug Stores LLC, Lanham, Maryland (TA-W-72,251J); SUPERVALU, Inc., IT and...

  5. 75 FR 57504 - Amended Certification Regarding Eligibility To Apply for Worker Adjustment Assistance

    Science.gov (United States)

    2010-09-21

    ... New Albertsons, Inc., Lanham, Maryland SUPERVALU, Inc., IT and Finance Departments, Including Workers...,251I); SUPERVALU, Inc., IT and Finance Departments, Lanham, Maryland (TA-W- 72,251J); SUPERVALU, Inc..., including workers whose unemployment insurance (UI) wages are paid through New Albertsons, Inc.,...

  6. 76 FR 2711 - Amended Certification Regarding Eligibility To Apply for Worker Adjustment Assistance

    Science.gov (United States)

    2011-01-14

    ..., Ultimate Staffing (Roth Staffing Companies) and Aerotek, Cromwell, Connecticut TA-W-71,054D Apria... Ultimate Staffing (Roth Staffing Companies) and Aerotek (TA-W 71,054C). The notice of amended... Employment Resources, Inc., d/b/a Corestaff and Leafstone, Ultimate Staffing (Roth Staffing Companies)...

  7. 75 FR 76491 - Investigations Regarding Certifications of Eligibility To Apply for Worker Adjustment Assistance

    Science.gov (United States)

    2010-12-08

    ............ 11/10/10 10/15/10 (Union). 74858 Benchmark Electronics Nashua, NH 11/10/10 11/08/10 (Company). 74859... Buchanan, MI 11/08/10 11/02/10 (Company). 74843 Jacuzzi Group Worldwide Chino Hills, CA....... 11/08/10 11/03/10 (Company). 74844 Cooper Lighting (Company).. Americus, GA 11/08/10 11/05/10 74845 J....

  8. 76 FR 50268 - Amended Certification Regarding Eligibility To Apply for Worker Adjustment Assistance

    Science.gov (United States)

    2011-08-12

    ... Reporting to Armonk, NY TA-W-73,218A International Business Machines Corporation, Web Strategy and... Armonk, NY. In accordance with Section 223 of the Trade Act of 1974, as amended (``Act''), 19 U.S.C. 2273... various states in the United States reporting to Armonk, New York. The workers are engaged in...

  9. 75 FR 16987 - Trade Adjustment Assistance; Merit Staffing of State Administration and Allocation of Training...

    Science.gov (United States)

    2010-04-02

    ..., as needed, to assure high quality performance. (d) Retaining employees on the basis of the adequacy... being eligible for training benefits, and in part because in past times of high program participation... services required to return to work, no matter where he or she enters the system, and...

  10. 78 FR 74164 - Notice of Determinations Regarding Eligibility To Apply for Worker Adjustment Assistance

    Science.gov (United States)

    2013-12-10

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF LABOR...' separation or threat of separation and to the decline in the sales or production of such firm; or II. Section... Act have been met. TA-W number Subject firm Location Impact date 83,133 Alkco, Philips Lighting,...

  11. 76 FR 2713 - Notice of Determinations Regarding Eligibility To Apply for Worker Adjustment Assistance

    Science.gov (United States)

    2011-01-14

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF LABOR...' separation or threat of separation and to the decline in the sales or production of such firm; or II. Section..., Working On- Siloam Springs, AR.. November 22, 2009. Site at Lay-Z-Boy. 74,916 Philips Luminaries...

  12. 78 FR 69880 - Notice of Determinations Regarding Eligibility To Apply for Worker Adjustment Assistance

    Science.gov (United States)

    2013-11-21

    ... Recycling Holdco, LLC. The following certifications have been issued. The requirements of Section 222(a)(2... Piana Stafford Springs, CT December 15, 2013 S.P.A., Textile Division. ] The following...

  13. 77 FR 67403 - Notice of Determinations Regarding Eligibility To Apply for Worker Adjustment Assistance

    Science.gov (United States)

    2012-11-09

    ... Experian Marketing Schaumburg, IL....... September 20, 2011. Solutions, Data Marketing Service Division........ September 25, 2011. Manufacturing Company, dba TTI Flooring Care N.A., Hoover, Inc. 82,010 Dell Marketing...

  14. 78 FR 63499 - Investigations Regarding Eligibility To Apply for Worker Adjustment Assistance

    Science.gov (United States)

    2013-10-24

    .../One-Stop).... Pipestone, MN......... 09/16/13 09/13/13 83082 DST Retirement Solutions Jefferson City...). 83096 Newark Recycled Paperboard Greenville, PA........ 09/19/13 09/18/13 Solutions (Workers). 83097 SB... Medical Center, Escondido, CA......... 09/19/13 09/04/13 Medical Transcription Workers (Workers)....

  15. 76 FR 51432 - Notice of Determinations Regarding Eligibility To Apply for Worker Adjustment Assistance and...

    Science.gov (United States)

    2011-08-18

    ... workers cannot be covered by more than one certification at a time. TA-W-80,012; Siemens Medical Solutions... foreign country) have not been met. TA-W-80,015; ACS Commercial Solutions, Inc., Liberty, Kentucky...

  16. 78 FR 771 - Notice of Determinations Regarding Eligibility To Apply for Worker Adjustment Assistance

    Science.gov (United States)

    2013-01-04

    .... Incorporated, HFAB sand HBUMP Manufacturing and Testing, Volt Workforce Solutions. 82,161 Remington Medical... Aluminum Hannibal, OH......... October 22, 2012. Corporation, I.C. Staffing Solutions LLC and Winans... Technologies, Eco Energy Solutions. 81,965 Melco Engraving, Inc...... Rochester Hills, MI.. 81,975...

  17. 75 FR 52987 - Investigations Regarding Certifications of Eligibility To Apply for Worker Adjustment Assistance

    Science.gov (United States)

    2010-08-30

    ... substantial interest in the subject matter of the investigations may request a public hearing, provided such... requested under the Freedom of Information Act. Requests may be submitted by fax, courier services, or mail............ 08/11/10 08/06/10 (Company). 74505 Neff Motivation, Inc. Unadilla, GA 08/11/10 08/09/10...

  18. 76 FR 30393 - Amended Certification Regarding Eligibility To Apply for Worker Adjustment Assistance

    Science.gov (United States)

    2011-05-25

    ... in Texas Houston and Plano (Two Locations), Texas Teleworkers In Denton, Texas TA-W-74,530H Hewlett...), Three Locations in Texas: Houston and Plano (Two Locations), Texas, Teleworkers in Denton, Texas (TA-W... (TA-W-74,530E); Blue Bell, Pennsylvania (TA-W-74,530F); Houston and Plano (two locations), Texas,...

  19. 75 FR 10324 - Investigations Regarding Certifications of Eligibility To Apply for Worker Adjustment Assistance

    Science.gov (United States)

    2010-03-05

    ... 73383 Conner Steel (State)........ San Angelo, TX......... 02/01/10 01/29/10 73384 B&K Trucking (State... Scope (Wkrs). 73395 SWR Inc./Roddie Transport San Angelo, TX......... 02/02/10 02/01/10 (State). 73396... (State). 73399 National Oilwell Varco San Angelo, TX......... 02/02/10 02/01/10 (State). 73400...

  20. 76 FR 72979 - Investigations Regarding Certifications of Eligibility To Apply for Worker Adjustment Assistance...

    Science.gov (United States)

    2011-11-28

    ... Corporation (Union). 81011 Cyberdyne Inc. (Workers)... Monongahela, PA....... 10/25/11 10/24/11 81012 Maersk Line, A Subsidiary The Woodlands, TX..... 10/25/11 10/24/11 of A.P. Moller Maersk (Company). 81013 Maersk Line (Company)...... Miami, FL 10/25/11 10/24/11 81014 Maersk Line (Company)...... Charlotte,...

  1. 77 FR 28901 - Amended Certification Regarding Eligibility To Apply for Worker Adjustment Assistance; The UBS...

    Science.gov (United States)

    2012-05-16

    ... UBS-GLB (Americas), Inc., Formerly Known as Brinson Partners, Inc., Corporate Center Division, Group... Reporting to Jersey City, NJ In accordance with Section 223 of the Trade Act of 1974, as amended (``Act... known as UBS Financial Services, Inc., and/or UBS-GLB (Americas), Inc., ] Corporate Center...

  2. 76 FR 76184 - Notice of Determinations Regarding Eligibility To Apply for Worker Adjustment Assistance

    Science.gov (United States)

    2011-12-06

    ...,274 OmniVision Technologies Boulder, CO July 8, 2010. Inc., Optics Division. 80,311 Verizon Business... Scranton, PA July 27, 2010. America Corporation, Global Trade Operations Import Letter, etc....

  3. 77 FR 1952 - Investigations Regarding Certifications of Eligibility To Apply for Worker Adjustment Assistance...

    Science.gov (United States)

    2012-01-12

    .../05/11 12/02/11 Stop). 81135 Peninsula Daily News Port Angeles, WA...... 12/05/11 11/29/11 (Workers...). Newton, NC 12/30/11 12/28/11 81202 TE Connectivity Medical Wilsonville, OR....... 12/30/11...

  4. 75 FR 15736 - Investigations Regarding Certifications of Eligibility To Apply for Worker Adjustment Assistance

    Science.gov (United States)

    2010-03-30

    ........ 02/26/10 02/22/10 (Wkrs). 73578 Burns Industrial Group Strongsville, OH...... 02/26/10 02/19/10 (Comp). 73579 Consolidated Glass and Galax, VA 02/26/10 02/25/10 Mirror Corporation (Comp). 73580...

  5. 75 FR 7031 - Notice of Determinations Regarding Eligibility To Apply for Worker Adjustment Assistance

    Science.gov (United States)

    2010-02-16

    ... and Onesource, Wilkes-Barre, PA, June 16, 2008. TA-W-71,357; Moyno, Inc., Fluid Management Group...; Keane, Inc., Keane International, Inc., Syracuse, NY, September 9, 2008. TA-W-72,405; Cadmus Journal..., NY, September 28, 2008. TA-W-72,620; Brand Science, LLC, Dandridge, TN, October 19, 2008....

  6. 75 FR 21353 - Notice of Determinations Regarding Eligibility To Apply for Worker Adjustment Assistance

    Science.gov (United States)

    2010-04-23

    ... International, Office Team/Robert Half and Volt Staffing, White Bear Lake, MN, October 6, 2008 TA-W-72,529...-71,038: General Pattern Company, Ham Lake, MN TA-W-71,074: American Roller Bearing & Manufacturing Co...: Legacy, Inc., Winston-Salem, NC TA-W-72,788: Barnes Aerospace, Inc., Ceramics Division, Windsor, CT...

  7. 78 FR 69884 - Investigations Regarding Eligibility To Apply for Worker Adjustment Assistance

    Science.gov (United States)

    2013-11-21

    ... Corporation (State/ Colorado Springs, CO.. 10/28/13 10/24/13 One-Stop). 83175 John Wiley and Sons, Inc...-Clydeunion Pumps Battle Creek, MI...... 10/31/13 10/22/13 (Workers). 83188 John Wiley & Sons...

  8. 75 FR 5148 - Investigations Regarding Certifications of Eligibility To Apply for Worker Adjustment Assistance

    Science.gov (United States)

    2010-02-01

    ... Rock, TX........ 12/28/09 12/18/09 73153 Kimberly-Clark Global Neenah, WI 12/28/09 12/18/09 Sales, Inc.../28/09 Company (Wkrs). 73187 Cascade Wood Products White City, OR........ 12/30/09 12/18/09...

  9. 75 FR 5349 - Investigations Regarding Certifications of Eligibility To Apply for Worker Adjustment Assistance

    Science.gov (United States)

    2010-02-02

    ... appropriate, to the determination of the date on which total or partial separations began or threatened to...). 73098 Valspar Coatings (Wkrs).... High Point, NC........ 12/15/09 11/24/09 73099 Siemen Medical.../09 Processing/First Tennessee Bank (Rep). 73119 Crown Paper Box (Comp)..... Indianapolis, IN.........

  10. 78 FR 54490 - Investigations Regarding Eligibility To Apply for Worker Adjustment Assistance

    Science.gov (United States)

    2013-09-04

    ..., MO......... 08/13/13 08/09/13 Technologies (Workers). 82976 CQ Sourcing, Warehouse New Castle, IN... 08/08/13 82992 The Electric Materials North East, PA......... 08/15/13 08/14/13 Company (Company...). 82997 H&T Waterbury, Inc. Waterbury, CT 08/16/13 08/15/13 (Company). 82998 Innovative Dental...

  11. 76 FR 58044 - Amended Certification Regarding Eligibility To Apply for Worker Adjustment Assistance; The Mega...

    Science.gov (United States)

    2011-09-19

    ...., Premius Credit Corp., Socrates, Inc., Sogeti USA, LLC, the Z Group, Inc., Verizon, Viant Payments Systems... Services, KFORCE, Microsoft, Pariveda Solutions, Inc., Perot Systems Corp., Premium Credit Corp., Socrates... Credit Corp., Socrates, Inc., Sogeti USA, LLC, The Z Group, Inc., Verizon, Viant Payments Systems,...

  12. 75 FR 34175 - Notice of Determinations Regarding Eligibility To Apply for Worker Adjustment Assistance

    Science.gov (United States)

    2010-06-16

    ..., Communications Computer Comsumer Electronics, Norwood, MA TA-W-72,176A: The Boeing Company, Shared Services Group...: JP Morgan Chase, Fort Worth, TX TA-W-73,498: ADC Telecommunications, Shakopee, MN TA-W-73,930:...

  13. 75 FR 10325 - Investigations Regarding Certifications of Eligibility To Apply for Worker Adjustment Assistance

    Science.gov (United States)

    2010-03-05

    ... 02/08/10 California, LLC (Comp). 73498 ADC Telecommunications Shakopee, MN 02/18/10 02/08/10 (Comp...)..... Des Moines, IA......... 02/18/10 02/10/10 73504 Telscape Communication, Inc. Monrovia, CA 02/18/10...

  14. 78 FR 55757 - Notice of Determinations Regarding Eligibility To Apply for Worker Adjustment Assistance

    Science.gov (United States)

    2013-09-11

    ... Processing (ADP)-- San Dimas, CA Corporate, Corporate Finance, Kforce, Inc. and Horizon Corporate Consultants...,966 Kohl's Department Stores, Inc., Milwaukee, WI....... August 7, 2012. Finance Department, Kforce..., Apex Systems, Horizon, etc. 82,828B Automatic Data Processing (ADP), San Dimas, CA Inc.,...

  15. 78 FR 49293 - Notice of Determinations Regarding Eligibility To Apply for Worker Adjustment Assistance

    Science.gov (United States)

    2013-08-13

    ..., 2012. Finance Group, Midwest Staffing. 82,778 Energizer, Adecco Westlake, OH........ June 3, 2012 82,805 Citi, Corporate Finance for New York, NY........ June 11, 2012. Operations & Technology, Corporate Realty Services. 82,805A Citi, Corporate Finance for Fort Lauderdale, FL. June 11, 2012....

  16. 75 FR 7043 - Investigations Regarding Certifications of Eligibility To Apply for Worker Adjustment Assistance

    Science.gov (United States)

    2010-02-16

    ... 01/27/10 01/25/10 73369 Key Energy (State)......... Houston, TX 01/27/10 01/22/10 73370 Thomson Reuters (Wkrs)..... Independence, OH...... 01/27/10 01/26/10 73371 The State Media Company Columbia, SC...

  17. 77 FR 14832 - Notice of Determinations Regarding Eligibility To Apply for Worker Adjustment Assistance

    Science.gov (United States)

    2012-03-13

    ... Corporation, Ball Packaging Corporation, leased workers from Kelly Services. 81,269 Cummins Filtration, A... Corporation, Water Suffolk, VA......... January 30, 2011. Solutions, Nextsource, Inc.. 81,286 CHF Industries............ February 1, 2011. Texas Division, Adecco and Its Quest. 81,301 Massachusetts Mutual Life Springfield,...

  18. 78 FR 73886 - Notice of Determinations Regarding Eligibility To Apply for Worker Adjustment Assistance

    Science.gov (United States)

    2013-12-09

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF LABOR Employment and Training Administration Notice of Determinations Regarding Eligibility To Apply for Worker... date 83,130 Harte Hanks Shoppers Inc Brea, CA 83,155 Veolia Water Facility, Jackson Jackson,...

  19. 76 FR 179 - Notice of Determinations Regarding Eligibility To Apply for Worker Adjustment Assistance

    Science.gov (United States)

    2011-01-03

    .... WellPoint Companies, Blue Cross of CA, Leased Workers from Bender, etc. 74,607A WellPoint, Inc., The... Bender, etc. 74,607B WellPoint, Inc., The Thousand Oaks, CA........ September 7, 2009. WellPoint Companies, Blue Cross of CA, Leased Workers from Bender, etc. 74,714 Quest Diagnostics, Inc.,...

  20. 77 FR 8279 - Notice of Determinations Regarding Eligibility To Apply for Worker Adjustment Assistance

    Science.gov (United States)

    2012-02-14

    ... separated; (2) The workers' firm is a Supplier or Downstream Producer to a firm that employed a group of...-- (A) The workers' firm is a supplier and the component parts it supplied to the firm described in... Group International Division. 81,138 Keystone Automotive Exeter, PA February 13, 2010. Operations,...

  1. 78 FR 34672 - Notice of Determinations Regarding Eligibility To Apply for Worker Adjustment Assistance

    Science.gov (United States)

    2013-06-10

    ... separated, or are threatened to become totally or partially separated; (2) The workers' firm is a Supplier... service that was the basis for such certification; and (3) Either-- (A) The workers' firm is a supplier..., KY...... March 1, 2012. Manufacturing, LLC, Automotive Electronics and Interiors, Johnson...

  2. 77 FR 61029 - Notice of Determinations Regarding Eligibility To Apply for Worker Adjustment Assistance

    Science.gov (United States)

    2012-10-05

    ... separated; (2) The workers' firm is a Supplier or Downstream Producer to a firm that employed a group of...-- (A) The workers' firm is a supplier and the component parts it supplied to the firm described in... date 81,916 Veolia ES Industrial Shreveport, LA........ Services, Inc. 81,917 Automotive...

  3. 76 FR 77555 - Notice of Determinations Regarding Eligibility To Apply for Worker Adjustment Assistance

    Science.gov (United States)

    2011-12-13

    ... date 80,306 Jem Sportswear, Inc., San Fernando, CA..... July 19, 2010. Affordable Staffing. 80,365... El Paso, TX July 12, 2010. 80,336 Dell Inc., Dell Financial Austin, TX July 18, 2010. Services...

  4. 78 FR 28634 - Notice of Determinations Regarding Eligibility To Apply for Worker Adjustment Assistance

    Science.gov (United States)

    2013-05-15

    ..., PA....... January 30, 2012. Inc., Plants 18, 19 and 76, Owens- Brockway Packaging, Inc. 82,619..., MA..... Co., Inc., D.R. Plourde, Spherion, Ranstad, Sourceright. 82,638 New Mexico Farmers Markets..., Frostburg, MD. Specialty Business Unit, Xerox Business Services, LLC. 82,380 Red Rock Medical Billing...

  5. 76 FR 37154 - Notice of Determinations Regarding Eligibility To Apply for Worker Adjustment Assistance and...

    Science.gov (United States)

    2011-06-24

    ... or a shift in production to Mexico or Canada) of the Trade Act have been met. None Affirmative...; Holcim (US), Inc., Catskill Plant, Holcim LTD, On-Site Leased Workers of Manpower, Catskill, NY: April 4...)(3)(A)(ii) of the Trade Act have been met. TA-W-80,092; Covidien, formerly Aspect Medical, R & MS...

  6. 75 FR 32221 - Notice of Determinations Regarding Eligibility To Apply for Worker Adjustment Assistance

    Science.gov (United States)

    2010-06-07

    ...+Hummel Advanced Filtration Concepts, Inc., Louisville, KY: January 21, 2009. TA-W-73,373: FLSmidth...., Carlsbad, CA: February 5, 2009. TA-W-73,477: International Game Technology (IGT), Machine Accounting...

  7. 76 FR 2716 - Notice of Determinations Regarding Eligibility To Apply for Worker Adjustment Assistance

    Science.gov (United States)

    2011-01-14

    ..... November 9, 2009. Pool Table Company. ] 74,912 Thomson Reuters (Tax & Accounting), Inc., Rochester, NY............ November 3, 2009. Career Concepts Staffing Services, etc. 74,846 Mayflower Vehicle Systems, LLC, The...

  8. 78 FR 70583 - Investigations Regarding Eligibility To Apply for Worker Adjustment Assistance

    Science.gov (United States)

    2013-11-26

    ...., Corporate Greenwood Village, CO.... 11/07/13 11/06/13 Accounting and Finance Administration (Company). 83204...-Stop). 83210 Kinetic Concepts, Inc. Charlotte, NC 11/08/13 11/07/13 (Company). 83211 Creavey...

  9. 75 FR 20392 - Investigations Regarding Certifications of Eligibility To Apply for Worker Adjustment Assistance

    Science.gov (United States)

    2010-04-19

    ... Vernon Hills, IL...... 03/11/10 03/10/10 Manufacturing (Wkrs). 73686 MWH Americas (Human Broomfield, CO........ 03/11/10 03/03/10 Resources (Wkrs). 73687 Somerset Plastics, Inc. Somerset, PA 03/11/10...

  10. 78 FR 61390 - Notice of Determinations Regarding Eligibility To Apply for Worker Adjustment Assistance

    Science.gov (United States)

    2013-10-03

    ... Department. 82,921 Staples, Inc., Human Resources Framingham, MA...... July 18, 2012. Services Division, BTHR......... August 1, 2012. Addison Group and Robert Half Accounting. 82,980 Sunrise Medical, Labor Max Staffing... date 82,959 Global Resource Services LLC....... Darrington, WA...... 83,013 Graymont St. Helens,...

  11. 75 FR 34178 - Investigations Regarding Certifications of Eligibility To Apply for Worker Adjustment Assistance

    Science.gov (United States)

    2010-06-16

    ..., Inc. (State/ One-Stop). 74142 World Color (Workers)... Schaumburg, IL..... 05/25/10 05/21/10. 74143 Providence Watch Cranston, RI....... 05/25/10 05/13/10. Hospital (Workers). 74144 Hoffmann La Roche...

  12. 75 FR 70699 - Notice of Determinations Regarding Eligibility To Apply for Worker Adjustment Assistance

    Science.gov (United States)

    2010-11-18

    ........... Hospital. 74,595 Connect North America Presque Island, ME. U.S.A., Inc., Black Diamond Financial...,684 World Color (USA), LLC, Clarksville, TN.... Quad-Graphics, Inc. I hereby certify that...

  13. 77 FR 44679 - Notice of Determinations Regarding Eligibility To Apply for Worker Adjustment Assistance

    Science.gov (United States)

    2012-07-30

    ... Washington, PA June 5, 2011. Global Relocation Services, Client Accounting Division, Accountemps and Quad. 81... Staffing. 81,770 Hartford Southington, CT June 29, 2011. Financial Services Group, Inc.,...

  14. 77 FR 39265 - Notice of Determinations Regarding Eligibility To Apply for Worker Adjustment Assistance

    Science.gov (United States)

    2012-07-02

    ... Location Impact date 81,385 Pfizer Therapeutic Groton, CT February 27, 2011 Research, Pfizer Worldwide..., 2011 Assembly Systems LLC, Accounting Division, Atlas Copco Ab, Reliance One. 81,612 WellPoint, Inc., Care North Haven, CT..... May 14, 2011 Management UM Intake, UI Wages Reported Through...

  15. 77 FR 29363 - Notice of Determinations Regarding Eligibility To Apply for Worker Adjustment Assistance

    Science.gov (United States)

    2012-05-17

    .... Automotive Service Delivery Division, Accounting Services, PRO Unlimited. 81,349 Alcatel-Lucent USA, Inc., D..., Finance and Accounting Team. 81,449 RR Donnelley, A Subsidiary of RR Glen Mills, PA..... March 22, 2011... Service Delivery Division. 81,459P International Business Machines Southbury, CT...... March 29,...

  16. 77 FR 25199 - Notice of Determinations Regarding Eligibility To Apply for Worker Adjustment Assistance

    Science.gov (United States)

    2012-04-27

    ... Lenox, IL........ November 25, 2011. Lenox Production Division, Cable Tie Division, Areotek, Inc. 81,425... separated; (2) The sales or production, or both, of such firm have decreased absolutely; and (3) One of the... separation and to the decline in the sales or production of such firm; or II. Section 222(a)(2)(B) all of...

  17. 75 FR 39046 - Notice of Determinations Regarding Eligibility To Apply for Worker Adjustment Assistance

    Science.gov (United States)

    2010-07-07

    ... been met. TA-W No. Subject firm Location Impact date 72,851 General Motors Milford, MI October 20, 2008... Holdings Company. 73,176 Valeo Electrical Systems, Troy, MI December 8, 2008. Inc., Wiper Systems Division...., Aerospace Div., Purchasing Dept., Leased Workers Manpower International. The following certifications...

  18. 75 FR 51846 - Notice of Determinations Regarding Eligibility To Apply for Worker Adjustment Assistance

    Science.gov (United States)

    2010-08-23

    ..., Inc., Emerson Electric Company. 73,975 CareFusion 209, Middleton, WI April 6, 2009. Incorporated.... Company. 73,689 General Motors Component Kokomo, IN February 15, 2010. Holdings, LLC, General Motors... 73,683 Contour Aerospace Everett, WA Corporation, a division of Vought Aircraft Industries....

  19. 76 FR 81987 - Notice of Determinations Regarding Eligibility To Apply for Worker Adjustment Assistance

    Science.gov (United States)

    2011-12-29

    ... Aerospace Sidney, NY......... February 13, 2010. Corporation, Superior Technical Resource, Staffworks...... February 13, 2010. (Wackenhut) and Ozark Motor Lines, Working On- Site at Sanyo Manufacturing Corporation.... Corporation, QPS Employment Group. 81,111 Ametek National Controls West Chicago, IL... October 9,...

  20. 76 FR 10396 - Notice of Determinations Regarding Eligibility To Apply for Worker Adjustment Assistance

    Science.gov (United States)

    2011-02-24

    .... Teleworkers Across Oregon. 74,849C ILevel By Weyerhaeuser, Carlsbad, Fontana, October 24, 2009. Residential............ Security Imaging Systems Division; Analogic Corporation Consolidated. 74,664 Joseph T. Ryerson and...

  1. 78 FR 77498 - Notice of Determinations Regarding Eligibility To Apply for Worker Adjustment Assistance

    Science.gov (United States)

    2013-12-23

    ... Technology Puerto Rico, Inc. Aguadilla, PR....... August 1, 2012. 83,132 Citibank, N.A., Enterprise New York... Citibank, N.A., Enterprise Tampa, FL October 11, 2012. Operations & Technology, Citi Procurement,...

  2. 75 FR 3928 - Notice of Determinations Regarding Eligibility To Apply for Worker Adjustment Assistance

    Science.gov (United States)

    2010-01-25

    ...: July 15, 2008. TA-W-72,339; Eastman Kodak Company, Finance & Accounting Div., Adecco, Dayton, OH... Automation Division, Spring House, PA: November 5, 2008. TA-W-70,525A; Yahoo Inc., Finance Division/Leased Workers from Workforce Logic, Burbank, CA: May 18, 2008. TA-W-70,525B; Yahoo Inc., Finance...

  3. 78 FR 21152 - Notice of Determinations Regarding Eligibility To Apply for Worker Adjustment Assistance

    Science.gov (United States)

    2013-04-09

    .... 82,406 360 Enterprises, Inc., Mesa, AZ DBA Textlinkbrokers.com , National PEO, LLC. ] 82,409 Dominion... Sparrows Point, MD.. Technologies of Baltimore, LLC, Magnus International Group, Steel Sparrows Point...

  4. 76 FR 40400 - Notice of Determinations Regarding Eligibility To Apply for Worker Adjustment Assistance and...

    Science.gov (United States)

    2011-07-08

    ...., Pontotoc, MS: March 22, 2010. TA-W-80,139; Electrolux Home Products, Inc., Webster City, IA: June 26, 2011... Company, Inc. (NESL), Erie, PA. TA-W-80,074; AES Westover, LLC, Johnson City, NY. TA-W-80,103; HiRel..., OH. TA-W-80,131; Invensys Operations Management, Irvine, CA. TA-W-80,170; Getty Images, Los...

  5. 78 FR 1258 - Investigations Regarding Eligibility to Apply for Worker Adjustment Assistance

    Science.gov (United States)

    2013-01-08

    ... Claire, 11/13/12 11/09/12 (State/One-Stop). WI. 82146 Precision Dynamics San Fernando, CA 11/13/12 11/09/12 Corporation (State/One- Stop). 82147 Pioneer Press (State/One- Saint Paul, MN 11/13/12...

  6. 75 FR 38139 - Notice of Determinations Regarding Eligibility To Apply for Worker Adjustment Assistance

    Science.gov (United States)

    2010-07-01

    ... Services, etc. 74,027 UPS Supply Chain Solutions, Dunmore, PA April 21, 2009. United Parcel Service, Leased... produced or services supplied by such firm have increased; (B) Imports of articles like or directly... directly competitive with articles which are produced directly using services supplied by such firm,...

  7. 76 FR 176 - Amended Certification Regarding Eligibility To Apply for Worker Adjustment Assistance

    Science.gov (United States)

    2011-01-03

    ... experience, solutions, engineering, supply chain, research, and product development services for personal...), Customer Warranty, Emerging Business, Supply Chain, Volume Operations, Worldwide Sales, and Americas Region... Group--Desktop (Fort Collins only), Customer Warranty, Emerging Business, Supply Chain,...

  8. 77 FR 40639 - Notice of Determinations Regarding Eligibility To Apply for Worker Adjustment Assistance

    Science.gov (United States)

    2012-07-10

    ..., Service, Sony Supply Chain Solutions, Selectremedy, Staffmark, etc. 81,423A Sony Electronics, Inc., San... produced or services supplied by such firm have increased; (B) Imports of articles like or directly... directly competitive with articles which are produced directly using services supplied by such firm,...

  9. 76 FR 22730 - Notice of Determinations Regarding Eligibility To Apply for Worker Adjustment Assistance

    Science.gov (United States)

    2011-04-22

    ...... February 14, 2010. Manpower and Advance Staffing. 75,286 Moulton Logistics Management, Call Center Van Nuys.......... and Networks, Supply Chain Division. 75,289 American Food and Vending, Working On-Site at Union City... produced or services supplied by such firm have increased; (B) Imports of articles like or...

  10. 75 FR 67771 - Notice of Determinations Regarding Eligibility To Apply for Worker Adjustment Assistance

    Science.gov (United States)

    2010-11-03

    ... Automation Fort Smith, AR Engineering. 74,521 Johnson Material Hackett, AR Handling. The following...)(1); or (C) An affirmative final determination of material injury or threat thereof under section 705... Ashley, IN Company, Chemtura Corporation. 74,066 Ceva Logistics........ Plainfield, IN....... 74,244...

  11. 75 FR 75699 - Notice of Determinations Regarding Eligibility To Apply for Worker Adjustment Assistance

    Science.gov (United States)

    2010-12-06

    ...)(1); or (C) An affirmative final determination of material injury or threat thereof under section 705... Newspapers, LLC; Production. 74,728 Dresser Incorporated, Flow Avon, MA October 8, 2009. Technologies.... 74,873 HAVI Logistics North America. Lisle, IL. The following determinations...

  12. 78 FR 2288 - Notice of Determinations Regarding Eligibility To Apply for Worker Adjustment Assistance

    Science.gov (United States)

    2013-01-10

    ... Electrolux Home Care El Paso, TX Products Inc., Distribution Center. 82,180 Comcast Cable, West Morgan Hill, CA....... Division Customer Care. 82,188 PNC Bank, National Franklin, PA Association, Retail Bank. 82... Services Clarksburg, WV........ Corporation, Customer Service Clerk, General Clerk. 82,136 Peabody...

  13. 78 FR 8589 - Notice of Determinations Regarding Eligibility to Apply for Worker Adjustment Assistance

    Science.gov (United States)

    2013-02-06

    ...,197 Delta Air Lines, Inc., Seatac, WA. Reservation Sales and Customer Care Call Center. 82,197A Delta Air Lines, Inc., Sioux City, IA........ Reservation Sales and Customer Care Call Center. 82,216...

  14. 77 FR 47671 - Notice of Determinations Regarding Eligibility To Apply for Worker Adjustment Assistance

    Science.gov (United States)

    2012-08-09

    ... 11, 2011. Global Customer Care-Service Assurance, AT&T, Off-Site Workers at Mesa, AZ. 81,705A AT&T Services, Inc., Saint Louis, MO June 11, 2011. Global Customer Care-Service Assurance, AT&T, Off-Site Workers at St. Louis. 81,705B AT&T Services, Inc., San Ramon, CA June 11, 2011. Global Customer...

  15. 77 FR 70478 - Notice of Determinations Regarding Eligibility To Apply for Worker Adjustment Assistance

    Science.gov (United States)

    2012-11-26

    ...,025 Comcast Cable, Sacramento, CA.. October 1, 2011. West Division Customer Care. 82,037 The Bank of... Health, Carlstadt, Inc., Outbound NJ. Customer Service Team. 81,895A Medimedia Health, Yardley, Inc., Outbound PA. Customer Service Team. 82,074 Komax Solar, Inc., York, PA. Komax Holdings AG....

  16. 75 FR 30066 - Notice of Determinations Regarding Eligibility To Apply for Worker Adjustment Assistance

    Science.gov (United States)

    2010-05-28

    ... Business Machines (IBM), Global Business Services, Division 6C, Application Services), Sterling Forest, NY... percent of the production or sales of the workers' firm; or (B) A loss of business by the workers' firm...-Packard Company, Enterprise Business, Storage Works Division, Solutions Platform Division, Marlboro,...

  17. 78 FR 52978 - Notice of Determinations Regarding Eligibility to Apply for Worker Adjustment Assistance

    Science.gov (United States)

    2013-08-27

    ... Chicopee, MA Supplies Global Business Unit, R&D, Covidien PLC. 82,843 Goodyear Tire & Rubber Union City, TN... percent of the production or sales of the workers' firm; or (B) a loss of business by the workers' firm... June 26, 2012. Annuity Contact Center and New Business Operations, Corporate Brokers....

  18. 76 FR 10401 - Investigations Regarding Certifications of Eligibility To Apply for Worker Adjustment Assistance...

    Science.gov (United States)

    2011-02-24

    .../ Maynard, MA 02/07/11 02/03/11 One-Stop). 75180 CPL (Company) Buffalo, NY 02/07/11 02/04/11 75181 Sony DADC...). 75237 ComDel Innovation (Company) Wahpeton, ND 02/11/11 02/09/11 75238 NcNeil (Workers) Fort Washington... 02/07/11 Health (Workers). 75186 Stanley Black & Decker Jackson, TN 02/08/11 02/07/11...

  19. 76 FR 28813 - Notice of Determinations Regarding Eligibility To Apply for Worker Adjustment Assistance

    Science.gov (United States)

    2011-05-18

    ..., Empresas LLC, Medsorb. 75,225 ECI Telecom DND, Pittsburgh, PA...... February 3, 2010. Inc., Belcan Serv... After notice of the petitions was published in the Federal Register and on the Department's Web site, as....gov . These determinations also are available on the Department's Web site at...

  20. 78 FR 77501 - Investigations Regarding Eligibility To Apply for Worker Adjustment Assistance

    Science.gov (United States)

    2013-12-23

    ... (Company). 83258 Apex Tool Group (State/One- Garland, TX 12/04/13 12/03/13 Stop). 83259 Multi Packaging... Milwaukee, OR......... 12/05/13 11/26/13 (Workers). 83267 Titan Tire (Workers)....... Bryan, OH 12/05/13...

  1. 75 FR 10319 - Notice of Determinations Regarding Eligibility To Apply for Worker Adjustment Assistance

    Science.gov (United States)

    2010-03-05

    ... Performance Textiles, Greensboro Division, Greensboro, NC June 5, 2008 TA-W-71,602; Cooper Tools--Sumter... Titan Agency, Mount Vernon, NY. TA-W-71,600A; Gemological Institute of America, New York, NY....

  2. 75 FR 71459 - Notice of Determinations Regarding Eligibility To Apply for Worker Adjustment Assistance

    Science.gov (United States)

    2010-11-23

    ... National Default Title Services; Leased Workers. 74,203 Titan Tire Corporation, Bryan, OH May 20, 2009. Division of Titan International, Inc.. 74,278 St. Joseph Industries, Battle Creek, MI... June 10, 2009. Inc..., AL........ October 27, 2009. Apex Tool Group, LLC. 74,807 UView Ultraviolet Santa Ana,...

  3. 75 FR 38144 - Investigations Regarding Certifications of Eligibility To Apply For Worker Adjustment Assistance

    Science.gov (United States)

    2010-07-01

    .... Christiansburg, VA.... 06/08/10 05/27/10 (Wkrs). 74203 Titan Tire Corporation Bryan, OH 06/08/10 05/20/10 (Wkrs.../10/10 06/09/10 (State/One-Stop). 74226 Starn Tool & Manufacturing Meadville, PA......... 06/10/10...

  4. 78 FR 11229 - Investigations Regarding Eligibility To Apply for Worker Adjustment Assistance

    Science.gov (United States)

    2013-02-15

    .../08/13 (Workers). 82386 Mahle Engine Components US, McConnelsville, OH.... 01/30/13 01/29/13 LLC... (Company). 82392 ABB Inc. (Company)......... Mount Pleasant, PA.... 01/31/13 01/30/13 82393 Royal...

  5. 77 FR 23291 - Investigations Regarding Certifications of Eligibility To Apply for Worker Adjustment Assistance

    Science.gov (United States)

    2012-04-18

    ... Richmond, VA 03/30/12 03/29/12 Shield. Credentialing Administration (Company). BILLING CODE 4510-FN-P ... Employment and Training Administration Investigations Regarding Certifications of Eligibility To Apply for... Training Administration, has instituted investigations pursuant to Section 221 (a) of the Act. The...

  6. 77 FR 23509 - Notice of Determinations Regarding Eligibility To Apply for Worker Adjustment Assistance

    Science.gov (United States)

    2012-04-19

    ... American Compressor Engineering Group, Tecumseh Product, Manpower. 81,224 Catawissa Wood and Elysburg, PA... Advantage Resource Group. 81,422 Thermo Fisher Scientific Milwaukee, WI........ March 14, 2011....

  7. 78 FR 47780 - Notice of Determinations Regarding Eligibility to Apply for Worker Adjustment Assistance

    Science.gov (United States)

    2013-08-06

    ... 15, 2012. Harpercollins Publishers, Spartan Staffing, Wood Personnel, etc.. The following... Communications, Victorville, CA....... Inc., and Affiliates. ] 82,795 Thermo Fisher Scientific... Sun Prairie,...

  8. 78 FR 25305 - Notice of Determinations Regarding Eligibility To Apply for Worker Adjustment Assistance

    Science.gov (United States)

    2013-04-30

    ..., Marketing New York, NY February 26, 2012. Services, Tapfin, Manpower and Experis. 82,506L Experian, Global... (Experian Boston, MA February 26, 2012. Marketing Services), etc., Tapfin, Manpower and Experis. 82,506E..., 2012. Direct (etc.), Tapfin, Manpower and Experis. 82,506H Experian, Marketing El Segundo,...

  9. 75 FR 63509 - Notice of Determinations Regarding Eligibility To Apply for Worker Adjustment Assistance

    Science.gov (United States)

    2010-10-15

    ... report submitted to the President by the International Trade Commission under section 202(f)(1) with... Turner Industries and Go. 74,491 Acme Electric, Actuant Lumberton, NC........ August 15, 2010..., Leased Eden Prairie, MN..... July 22, 2009. Workers Masterson Personnel, Just in Case, etc. 74,471...

  10. 75 FR 11922 - Notice of Determinations Regarding Eligibility To Apply for Worker Adjustment Assistance

    Science.gov (United States)

    2010-03-12

    ... Division, Leased Workers from Pro Unlimited, Duluth, GA. October 15, 2008. TA-W-72,594; Heraeus Electro...; Teradyne, Inc., Semiconductor Test Div., CDI Talent Management, Richardson, TX. June 23, 2008....

  11. 75 FR 57980 - Notice of Determinations Regarding Eligibility To Apply for Worker Adjustment Assistance

    Science.gov (United States)

    2010-09-23

    ... Business Charlotte, NC....... February 16, 2009. Machines (IBM), Global Technology Services Delivery... Components Inc., Rancho Santa August 11, 2009. A Subsidiary of IMI, Margarita, CA. PLC, Leased Workers from Mattson, Axis Technology Group, etc. 74,527 Mahle Engine Components, Caldwell, OH........ August 10,...

  12. 76 FR 19468 - Notice of Determinations Regarding Eligibility To Apply for Worker Adjustment Assistance

    Science.gov (United States)

    2011-04-07

    ... City, IA........ February 14, 2010. Agents. 75,284 CGI Technologies and Andover, MA February 14, 2010..., 2010. PLC; Leased Workers from Bradley Hume, Black Diamond Networks, etc. 75,285A VisLink, Inc. (PMR), Vista, CA February 14, 2010. VisLink, PLC. 75,300 Key Plastics, LLC, Exterior Hartford City,...

  13. 76 FR 24914 - Notice of Determinations Regarding Eligibility To Apply for Worker Adjustment Assistance

    Science.gov (United States)

    2011-05-03

    ...Phillips Alaska Nikiski, AK Natural Gas Company, A Joint Venture with Marathon Oil; Kenai Plant. 75,312 R.J... Samuel Strapping Systems. 75,024 Havells USA, Inc., Mullins, SC Havells Netherlands, Havells India,...

  14. 75 FR 52982 - Notice of Determinations Regarding Eligibility To Apply for Worker Adjustment Assistance

    Science.gov (United States)

    2010-08-30

    ... Information Services, LLC 73,950 Auto Builders, Inc........ Ladson, SC 74,021 Diagnostic Staffing Pittsburgh... International. 72,936 Current Medicine Group, Philadelphia, PA November 19, 2008. LLC, Springs...

  15. 75 FR 26796 - Investigations Regarding Certifications of Eligibility To Apply for Worker Adjustment Assistance

    Science.gov (United States)

    2010-05-12

    ... (petitioners) Location institution petition 73952 Philips Lightolier Fall River, MA........ 04/19/10 04/13/10... Mercury of Winchester, KY........ 04/19/10 04/15/10 Winchester, Inc. (Company). 73956 Siemens IT Solutions...). 73973 Scientific Games South Barre, VT....... 04/22/10 04/08/10 International (Workers)....

  16. 75 FR 65518 - Notice of Determinations Regarding Eligibility To Apply for Worker Adjustment Assistance

    Science.gov (United States)

    2010-10-25

    ......... June 30, 2009. Products, Inc. 74,426 International Business Rochester, MN...... July 22, 2009. Machines.... Career Solutions, TEC Staffing. 74,611 Schneider Electric USA, Knightdale, NC..... August 27, 2009. Volt... Hanesbrands, Inc., Annapolis Winston-Salem, NC...... June 18, 2009. Drive Facility. Negative...

  17. 76 FR 43350 - Notice of Determinations Regarding Eligibility To Apply for Worker Adjustment Assistance and...

    Science.gov (United States)

    2011-07-20

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF LABOR... loss or business by the workers' firm with the firm (or subdivision) described in paragraph (2...: May 4, 2010. TA-W-80,229; Neff Motivation, Inc., Greenville, OH: June 13, 2010. TA-W-80,236;...

  18. 76 FR 50267 - Amended Certification Regarding Eligibility To Apply for Worker Adjustment Assistance

    Science.gov (United States)

    2011-08-12

    ... Associates, Phillips Engineering, Rockwell Engineering, Excel Logistics, and American Food and Vending. The... Associates, Phillips Engineering, Rockwell Engineering, Excel Logistics, and American Food and Vending... Corporation, Conestoga Rovers and Associates, Phillips Engineering, Rockwell Engineering, Excel Logistics,...

  19. 77 FR 1950 - Notice of Determinations Regarding Eligibility To Apply for Worker Adjustment Assistance

    Science.gov (United States)

    2012-01-12

    ..., dba Sikorsky Military Completion, Adecco, Aerotek, etc. 80,413 Flextronics, Flextronics Louisville, KY... February 13, 2010. 81,087 Burlington Basket Company. West Burlington, IA.. February 13, 2010. 81,115...

  20. 78 FR 769 - Notice of Determinations Regarding Eligibility To Apply for Worker Adjustment Assistance

    Science.gov (United States)

    2013-01-04

    ..., Entegee. 82,178 KEMET Electronics Simpsonville, SC.... November 26, 2011. Corporation, Accounts Payable Department, Accounts Receivable Department. 82,185 New Process Gear, Magna East Syracuse, NY... January...

  1. 76 FR 59168 - Amended Certification Regarding Eligibility To Apply for Worker Adjustment Assistance

    Science.gov (United States)

    2011-09-23

    ..., Deductions, Collections, Call Center, Information Technology, Accounts Payable, General Accounts, Financial Accounts, Payroll, and Employee Master Data Departments, Including On-Site Leased Workers From Adecco... Technology, Accounts Payable, General Accounts, Financial Accounts, Payroll, and Employee Master...

  2. Adjusting to motherhood: maternity care assistance during the postpartum period: how to help new mothers cope.

    NARCIS (Netherlands)

    Wiegers, T.A.

    2006-01-01

    The overall aim of postpartum care is to detect health problems of the mother and/or baby at an early stage, to encourage breastfeeding and to give families a good start. This paper presents an overview of recent literature about postpartum care in several developed countries and elaborates on the D

  3. 78 FR 70581 - Notice of Determinations Regarding Eligibility To Apply for Worker Adjustment Assistance

    Science.gov (United States)

    2013-11-26

    .... 83,064 IBM Corporation, Global Business Boulder, CO...... September 6, 2012. Services, Application... sales of the workers' firm; or (B) A loss of business by the workers' firm with the firm described...

  4. 78 FR 39776 - Notice of Determinations Regarding Eligibility To Apply for Worker Adjustment Assistance

    Science.gov (United States)

    2013-07-02

    ... Trade Commission as a member of a domestic industry in an investigation resulting in-- (A) an... Control Operations, Brown and Dunton. 82,709 Baxter Healthcare Largo, FL May 3, 2012. Corporation, Renal... Sacramento, CA........ May 9, 2012. Company, L.L.C., Campbell Soup Company. 82,730 Baxter Healthcare of...

  5. 76 FR 2719 - Investigations Regarding Certifications of Eligibility To Apply for Worker Adjustment Assistance

    Science.gov (United States)

    2011-01-14

    ...-Stop). 74992 SuperMedia, LLC (Workers)... Dallas, TX 12/14/10 12/13/10 74993 Baxter Healthcare..., TX 12/15/10 12/14/10 Insurance Company (State/ One-Stop). 74995 Bush Industries, Inc. Erie, PA 12/15/10 12/10/10 (Company). 74996 Manson Industries, Inc. Manson, IA 12/15/10 12/14/10 (Company)....

  6. 75 FR 62425 - Notice of Determinations Regarding Eligibility To Apply for Worker Adjustment Assistance

    Science.gov (United States)

    2010-10-08

    ... identified by name by the International Trade Commission as a member of a domestic industry in an... section 222 has not been met. TA-W No. Subject firm Location Impact date 73,983 Apria Healthcare, Redmond... City, NC Industries, Inc. 73,269 Grand Manor Furniture, Lenoir, NC Leased Workers Accuforce...

  7. 75 FR 3932 - Notice of Determinations Regarding Eligibility To Apply for Worker Adjustment Assistance

    Science.gov (United States)

    2010-01-25

    ..., East Millinocket, ME: September 15, 2008. TA-W-70,660; Gold Canyon Mining and Construction, LLC, Apache... Plating and Coatings, Phoenix Personnel, Wyandotte, MI: June 3, 2008. The following certifications...

  8. 75 FR 77666 - Notice of Determinations Regarding Eligibility To Apply for Worker Adjustment Assistance

    Science.gov (United States)

    2010-12-13

    ... Freeport-McMoran Copper Phoenix, AZ........ July 17, 2009. & Gold, Information Technology Department. 74.... Subject firm Location Impact date 74,119 Design Metal Plating, Emporium, PA....... May 11, 2009....

  9. 77 FR 28900 - Amended Certification Regarding Eligibility to Apply for Worker Adjustment Assistance

    Science.gov (United States)

    2012-05-16

    ... Enterprises, Inc., Middlebury, Indiana TA-W-81,004B Pace American Enterprises, Inc., Fitzgerald, Georgia TA-W... Enterprises, Inc., Fitzgerald, Georgia (TA-W- 81,004B); Pace American Enterprises, Inc., Lebanon, Oregon (TA-W...., Middlebury, Indiana (TA-W-81,004A), Pace American Enterprises, Inc., Fitzgerald, Georgia (TA-W-81,004B),...

  10. 78 FR 14360 - Investigations Regarding Eligibility To Apply for Worker Adjustment Assistance

    Science.gov (United States)

    2013-03-05

    ... HP Global Functions Palo Alto, CA 02/13/13 02/12/13 (Company). 82453 Dell Financial Services LLC... Russell Brands LLC/ Alexander City, AL..... 02/13/13 02/12/13 Decorations (Company). 82458 REC Silicon...

  11. 78 FR 63496 - Notice of Determinations Regarding Eligibility To Apply for Worker Adjustment Assistance

    Science.gov (United States)

    2013-10-24

    .... 83,019 Springs Global US, Inc., Lancaster, SC March 29, 2013. Grace Complex--Distribution Facility, Springs Global, Defender Industries. 83,022 The Spencer Turbine Company, Windsor, CT August 23, 2012..., Staffing Solutions. 83,071 Applied Discovery, Inc., Bellevue, WA August 26, 2012. Behind The Brand,...

  12. 77 FR 6588 - Notice of Determinations Regarding Eligibility To Apply for Worker Adjustment Assistance

    Science.gov (United States)

    2012-02-08

    ... Brands, St. Louis, MO.. February 13, Inc., Interstate 2010. Brands Corp., Resources Global Int'l, Ranstad... Corp., Resources Global Int'l, Ranstad Finance, etc. 81,029B......... Hostess Brands, Peoria, IL..... February 13, Inc., Interstate 2010. Brands Corp., Resources Global Int'l, Ranstad Finance, etc....

  13. 75 FR 20385 - Amended Certification Regarding Eligibility To Apply for Worker Adjustment Assistance

    Science.gov (United States)

    2010-04-19

    ... Workers from Comforce Corporation, Adecco, Multax, Inconen, CTS, Hi-Tec, Woods, Ciber, Kelly Services..., Multax, Inconen, CTS, Hi-Tec, Woods, Ciber, Kelly Services, Analysts International Corp, Comsys, Filter..., Inconen, CTS, Hi-Tec, Woods, Ciber, Kelly Services, Analysts International Corp, Comsys, Filter...

  14. 76 FR 13664 - Amended Certification Regarding Eligibility To Apply for Worker Adjustment Assistance

    Science.gov (United States)

    2011-03-14

    ... Software, Ciber, Inc., Engineering Technology Associates, Inc., TAC Transportation, the Bartech Group... Diamond Software, Ciber, Inc., Engineering Technology Associates, Inc., TAC Transportation, The...

  15. 76 FR 5833 - Amended Certification Regarding Eligibility to Apply for Worker Adjustment Assistance

    Science.gov (United States)

    2011-02-02

    ... SERVICES, CIBER, UC4 AND ENVISIONS INCLUDING OFF-SITE WORKERS ACROSS THE UNITED STATES, MALVERN..., Collegiate, Cornelius Professional Services, Ciber, UC4 and Envisions, including off-site workers across...

  16. 77 FR 46122 - Notice of Determinations Regarding Eligibility To Apply for Worker Adjustment Assistance

    Science.gov (United States)

    2012-08-02

    ... sales of the workers' firm; or (B) A loss of business by the workers' firm with the firm described in.... Industries, Inc.. 81,772 WellPoint, Inc., Sr. Indianapolis, IN...... July 2, 2011. Business Div. Claims Dept...., Cut and Sew Operations. 81,796 Adams Globalization, Austin, TX July 9, 2011. Transperfect...

  17. 77 FR 44682 - Investigations Regarding Eligibility To Apply for Worker Adjustment Assistance

    Science.gov (United States)

    2012-07-30

    ... Adams Globalization, a Austin, TX 07/12/12 07/09/12 Division of Transperfect, IDTP Department (Workers). 81797 International Business Endicott, NY 07/13/12 07/12/12 Machines (IBM) (State/One- Stop). 81798...

  18. 76 FR 61741 - Amended Certification Regarding Eligibility To Apply for Worker Adjustment Assistance; SYMANTEC...

    Science.gov (United States)

    2011-10-05

    ... Engineering Division, SQA Engineering, VCS and VCS-One Division, work in conjunction with each other, that the... and VCS-One Division, Austin, TX; SYMANTEC Corporation, the Enterprise Product and Services Group, SQA Engineering, VCS and VCS-One Division, Encryption Engineering Division, Including Remote Workers Across...

  19. 75 FR 71457 - Amended Certification Regarding Eligibility To Apply for Worker Adjustment Assistance

    Science.gov (United States)

    2010-11-23

    ... America, Global Parts Supply Chain Group, Including Leased Workers From QFLEX, North America Logistics... America Global Parts Supply Chain Group Including Leased Workers From QFLEX, North America Logistics, and... Global Parts Supply Chain Group Including Leased Workers From QFLEX, North America Logistics, and...

  20. 75 FR 70689 - Amended Certification Regarding Eligibility To Apply for Worker Adjustment Assistance

    Science.gov (United States)

    2010-11-18

    ... LLC, MGD Consulting, Inc., Case Interactive LLC., and Sapphire Technologies, Highlands Ranch, Colorado..., InfoQuest Consulting Group, CCSI Inc., ICONMA LLC, MGD Consulting, Inc., Case Interactive LLC., and... Resources Inc., Real Soft, Inforquest Consulting Group, CCSI Inc., ICONMA LLC, MGD Consulting, Inc.,...