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Sample records for adequately robust early

  1. Information about robustness, reliability and safety in early design phases

    DEFF Research Database (Denmark)

    Marini, Vinicius Kaster

    of attributes of robustness, reliability and safety. The uncertainty and ambiguity that are inherent to concept development impede the evaluation and improvement of attributes of robustness, reliability and safety in early design. A taxonomy was therefore developed to assess the information about...... these attributes that current methods require, and to address the need for clarity about design issues that result in risks. The concept development phase fosters ambiguity on how to satisfy requirements of robustness, reliability and safety, which is exacerbated by complexity in the individual solution...... alternatives. This prompts designers to reuse working principles that are inherently flawed, as they are liable to disturbances, failures and hazards. To address this issue, an approach based upon individual records of early design issues consists of comparing failures and benefits from prior working...

  2. Selection of adequate site location during early stages of construction project management: A multi-criteria decision analysis approach

    Science.gov (United States)

    Marović, Ivan; Hanak, Tomaš

    2017-10-01

    In the management of construction projects special attention should be given to the planning as the most important phase of decision-making process. Quality decision-making based on adequate and comprehensive collaboration of all involved stakeholders is crucial in project’s early stages. Fundamental reasons for existence of this problem arise from: specific conditions of construction industry (final products are inseparable from the location i.e. location has a strong influence of building design and its structural characteristics as well as technology which will be used during construction), investors’ desires and attitudes, and influence of socioeconomic and environment aspects. Considering all mentioned reasons one can conclude that selection of adequate construction site location for future investment is complex, low structured and multi-criteria problem. To take into account all the dimensions, the proposed model for selection of adequate site location is devised. The model is based on AHP (for designing the decision-making hierarchy) and PROMETHEE (for pairwise comparison of investment locations) methods. As a result of mixing basis feature of both methods, operational synergies can be achieved in multi-criteria decision analysis. Such gives the decision-maker a sense of assurance, knowing that if the procedure proposed by the presented model has been followed, it will lead to a rational decision, carefully and systematically thought out.

  3. Robust early pregnancy prediction of later preeclampsia using metabolomic biomarkers.

    LENUS (Irish Health Repository)

    Kenny, Louise C

    2012-01-31

    Preeclampsia is a pregnancy-specific syndrome that causes substantial maternal and fetal morbidity and mortality. The etiology is incompletely understood, and there is no clinically useful screening test. Current metabolomic technologies have allowed the establishment of metabolic signatures of preeclampsia in early pregnancy. Here, a 2-phase discovery\\/validation metabolic profiling study was performed. In the discovery phase, a nested case-control study was designed, using samples obtained at 15+\\/-1 weeks\\' gestation from 60 women who subsequently developed preeclampsia and 60 controls taking part in the prospective Screening for Pregnancy Endpoints cohort study. Controls were proportionally population matched for age, ethnicity, and body mass index at booking. Plasma samples were analyzed using ultra performance liquid chromatography-mass spectrometry. A multivariate predictive model combining 14 metabolites gave an odds ratio for developing preeclampsia of 36 (95% CI: 12 to 108), with an area under the receiver operator characteristic curve of 0.94. These findings were then validated using an independent case-control study on plasma obtained at 15+\\/-1 weeks from 39 women who subsequently developed preeclampsia and 40 similarly matched controls from a participating center in a different country. The same 14 metabolites produced an odds ratio of 23 (95% CI: 7 to 73) with an area under receiver operator characteristic curve of 0.92. The finding of a consistent discriminatory metabolite signature in early pregnancy plasma preceding the onset of preeclampsia offers insight into disease pathogenesis and offers the tantalizing promise of a robust presymptomatic screening test.

  4. Robust Early Pregnancy Prediction of Later Preeclampsia Using Metabolomic Biomarkers.

    LENUS (Irish Health Repository)

    Kenny, Louise C

    2010-09-13

    Preeclampsia is a pregnancy-specific syndrome that causes substantial maternal and fetal morbidity and mortality. The etiology is incompletely understood, and there is no clinically useful screening test. Current metabolomic technologies have allowed the establishment of metabolic signatures of preeclampsia in early pregnancy. Here, a 2-phase discovery\\/validation metabolic profiling study was performed. In the discovery phase, a nested case-control study was designed, using samples obtained at 15±1 weeks\\' gestation from 60 women who subsequently developed preeclampsia and 60 controls taking part in the prospective Screening for Pregnancy Endpoints cohort study. Controls were proportionally population matched for age, ethnicity, and body mass index at booking. Plasma samples were analyzed using ultra performance liquid chromatography-mass spectrometry. A multivariate predictive model combining 14 metabolites gave an odds ratio for developing preeclampsia of 36 (95% CI: 12 to 108), with an area under the receiver operator characteristic curve of 0.94. These findings were then validated using an independent case-control study on plasma obtained at 15±1 weeks from 39 women who subsequently developed preeclampsia and 40 similarly matched controls from a participating center in a different country. The same 14 metabolites produced an odds ratio of 23 (95% CI: 7 to 73) with an area under receiver operator characteristic curve of 0.92. The finding of a consistent discriminatory metabolite signature in early pregnancy plasma preceding the onset of preeclampsia offers insight into disease pathogenesis and offers the tantalizing promise of a robust presymptomatic screening test.

  5. Multiple giant succular and fusiform right and left coronary artery aneurysms after early and adequate treatment of atypical kawasaki disease with unusual presentation.

    Directory of Open Access Journals (Sweden)

    Mostafa Behjati-Ardakani

    2014-06-01

    Full Text Available The major complication of Kawasaki disease is coronary artery dilatation and aneurysm. It occurs in approximately 15-25% of untreated children with Kawasaki Disease. Early diagnosis and treatment with Intravenous immune globulin (IVIG and aspirin (ASA can reduce the incidence of coronary artery abnormality to 2%-5%. We report one case of Atypical Kawasaki Disease with Multiple giant coronary artery aneurysms despite early adequate treatment with IVIG and ASA.

  6. Robust and flexible mapping for real-time distributed applications during the early design phases

    DEFF Research Database (Denmark)

    Gan, Junhe; Pop, Paul; Gruian, Flavius

    2012-01-01

    We are interested in mapping hard real-time applications on distributed heterogeneous architectures. An application is modeled as a set of tasks, and we consider a fixed-priority preemptive scheduling policy. We target the early design phases, when decisions have a high impact on the subsequent...... in the functionality requirements are captured using “future scenarios”, which are task sets that model functionality likely to be added in the future. In this context, we derive a mapping of tasks in the application, such that the resulted implementation is both robust and flexible. Robust means that the application...

  7. Early warning of climate tipping points from critical slowing down: comparing methods to improve robustness.

    Science.gov (United States)

    Lenton, T M; Livina, V N; Dakos, V; van Nes, E H; Scheffer, M

    2012-03-13

    We address whether robust early warning signals can, in principle, be provided before a climate tipping point is reached, focusing on methods that seek to detect critical slowing down as a precursor of bifurcation. As a test bed, six previously analysed datasets are reconsidered, three palaeoclimate records approaching abrupt transitions at the end of the last ice age and three models of varying complexity forced through a collapse of the Atlantic thermohaline circulation. Approaches based on examining the lag-1 autocorrelation function or on detrended fluctuation analysis are applied together and compared. The effects of aggregating the data, detrending method, sliding window length and filtering bandwidth are examined. Robust indicators of critical slowing down are found prior to the abrupt warming event at the end of the Younger Dryas, but the indicators are less clear prior to the Bølling-Allerød warming, or glacial termination in Antarctica. Early warnings of thermohaline circulation collapse can be masked by inter-annual variability driven by atmospheric dynamics. However, rapidly decaying modes can be successfully filtered out by using a long bandwidth or by aggregating data. The two methods have complementary strengths and weaknesses and we recommend applying them together to improve the robustness of early warnings.

  8. Can Targeted Intervention Mitigate Early Emotional and Behavioral Problems?: Generating Robust Evidence within Randomized Controlled Trials.

    Directory of Open Access Journals (Sweden)

    Orla Doyle

    Full Text Available This study examined the impact of a targeted Irish early intervention program on children's emotional and behavioral development using multiple methods to test the robustness of the results. Data on 164 Preparing for Life participants who were randomly assigned into an intervention group, involving home visits from pregnancy onwards, or a control group, was used to test the impact of the intervention on Child Behavior Checklist scores at 24-months. Using inverse probability weighting to account for differential attrition, permutation testing to address small sample size, and quantile regression to characterize the distributional impact of the intervention, we found that the few treatment effects were largely concentrated among boys most at risk of developing emotional and behavioral problems. The average treatment effect identified a 13% reduction in the likelihood of falling into the borderline clinical threshold for Total Problems. The interaction and subgroup analysis found that this main effect was driven by boys. The distributional analysis identified a 10-point reduction in the Externalizing Problems score for boys at the 90th percentile. No effects were observed for girls or for the continuous measures of Total, Internalizing, and Externalizing problems. These findings suggest that the impact of this prenatally commencing home visiting program may be limited to boys experiencing the most difficulties. Further adoption of the statistical methods applied here may help to improve the internal validity of randomized controlled trials and contribute to the field of evaluation science more generally.ISRCTN Registry ISRCTN04631728.

  9. Early life DNA vaccination with the H gene of Canine distemper virus induces robust protection against distemper

    DEFF Research Database (Denmark)

    Jensen, Trine Hammer; Nielsen, Line; Aasted, Bent

    2009-01-01

    Young mink kits (n = 8)were vaccinated withDNA plasmids encoding the viral haemagglutinin protein (H) of a vaccine strain of Canine distemper virus (CDV). Virus neutralising (VN) antibodieswere induced after 2 immunisations and after the third immunisation all kits had high VN antibody titres...... demonstrate that early life DNA vaccination with the H gene of a CDV vaccine strain induced robust protective immunity against a recent wild type CDV....

  10. The pattern of robusticity among early Bronze Age groups of Central Europe: sex differences

    Czech Academy of Sciences Publication Activity Database

    Sládek, Vladimír; Berner, M.; Sailer, R.

    Supplement 36, - (2003), s. 194 ISSN 0002-9483. [Annual meeting of the American Association of Physical Anthropologists /72./. 23.04.2003-26.04.2003, Tempe] Institutional research plan: CEZ:AV0Z6093917 Keywords : biomechanical analysis * robusticity * Bronze Age Subject RIV: AC - Archeology, Anthropology , Ethnology

  11. A double constrained robust capon beamforming based imaging method for early breast cancer detection

    International Nuclear Information System (INIS)

    Xiao Xia; Xu Li; Li Qin-Wei

    2013-01-01

    Ultra-wideband (UWB) microwave images are proposed for detecting small malignant breast tumors based on the large contrast of electric parameters between a malignant tumor and normal breast tissue. In this study, an antenna array composed of 9 antennas is applied to the detection. The double constrained robust capon beamforming (DCRCB) algorithm is used for reconstructing the breast image due to its better stability and high signal-to-interference-plus-noise ratio (SINR). The successful detection of a tumor of 2 mm in diameter shown in the reconstruction demonstrates the robustness of the DCRCB beamforming algorithm. This study verifies the feasibility of detecting small breast tumors by using the DCRCB imaging algorithm. (electromagnetism, optics, acoustics, heat transfer, classical mechanics, and fluid dynamics)

  12. Nitrogen Fertilization for Optimizing the Quality and Yield of Shade Grown Cuban Cigar Tobacco: Required Nitrogen Amounts, Application Schedules, Adequate Leaf Nitrogen Levels, and Early Season Diagnostic Tests

    Directory of Open Access Journals (Sweden)

    Borges A

    2014-12-01

    Full Text Available Nitrogen (N fertilizers have a decisive influence on the yield and quality of tobacco. Yield, percentage of plant N, wrapper leaf quality, and nicotine content are all important quality characteristics in tobacco growing. This work is an attempt to provide a tool for optimizing mineral N nutrition for Cuban cigar tobacco, using a strategy that links N supply with leaf N concentration and wrapper yield. Similar approaches developed worldwide have mainly involved Virginia and Burley tobacco types but not Cuban cigar tobacco. The objective of the current work is to identify the effects of fertilizer N levels and timing of application on each of the mentioned quality factors for shade grown Cuban cigar tobacco. Another purpose is to explore the usefulness of a quick method of assessing the N status of plants based on measuring leaf transmission at two different wavelengths (650 and 940 nm. The experiments were done in the main tobacco growing area of Cuba (Vueltabajo. In each experiment, nine separate treatments were used covering different levels and times of fertilizer N application. The same experiment was carried out in three different years (2005-2006, 2006-2007, 2007-2008 but as the results were similar only one set of data is described (2006-2007. The patterns of response to N fertilizer of all four quality measurements, including yield and wrapper leaf quality, were similar in the different replications of the experiments. The optimal fertilizer level was 140-190 kg N/ha (40% applied on days 8-10 after transplanting and 60% on days 18-20 after transplanting. The optimal N concentration of leaves taken at the central foliar level of the middle stalk position was 4.3-4.7% at harvest time. Leaf transmission measurements by means of the SPAD-502 Chlorophyll Meter in the early stages of growth were correlated with leaf chlorophyll and N concentration and provide an excellent guide for predicting Cuban cigar tobacco wrapper leaf yield.

  13. Adequate doctor - patient communication

    Directory of Open Access Journals (Sweden)

    Janković Slobodan

    2013-01-01

    Full Text Available Communication process gives to physician necessary information for establishing diagnosis and prescribing therapy, and helps to a patient to gain confidence in his doctor and the prescribed treatment. The communication between doctor and his patient is enhanced by the following: openness and conscientiousness of the physician, serious approach to the patient, participation of the patient in decision-making, advanced age and higher education of the patient. On the other hand, communication is less efficient if the doctor has longer employment status, if he/her avoids disclosure of all relevant information to the patient, if he/her is emotionally separated from the patient, if the time for an encounter is limited, if the patient is passive and with unrealistic expectations, and if the doctor is expressing himself/herself unclearly. In order to improve communication with patients, doctors should follow these recommendations: keeping eye contact with a patient, releasing tension from his/her body language, taking detailed patient history with active listening and without interrupting of a patient, speaking clearly and slowly, using language understandable to a patient, treating patients with equality, disclosing all relevant information to the patient and sharing decisionmaking with the patient. Adequate communication between doctor and patient always brings better treatment outcomes.

  14. A robust prognostic gene expression signature for early stage lung adenocarcinoma

    DEFF Research Database (Denmark)

    Krzystanek, Marcin; Moldvay, Judit; Szüts, David

    2016-01-01

    Stage I lung adenocarcinoma is usually not treated with adjuvant chemotherapy; however, around half of these patients do not survive 5 years. Therefore, a reliable prognostic biomarker for early stage patients would be critical to identify those most likely to benefit from early additional treatm...... not given adjuvant therapy. Seven genes consistently obtained statistical significance in Cox regression for overall survival. The combined signature has a weighted mean hazard ratio of 3.2 in all cohorts and 3.0 (C.I. 1.3-7.4, p ...

  15. Parental death and bipolar disorder: a robust association was found in early maternal suicide

    DEFF Research Database (Denmark)

    Tsuchiya, Kenji; Agerbo, Esben; Mortensen, Preben Bo

    2005-01-01

    of a conditional logistic regression analysis. RESULTS: Among 947 subjects with bipolar disorder and 47,350 controls, those having experienced the parental suicide were significantly associated with an increased risk for BPD (incidence rate ratios: 1.83 [95% confidence interval: 1.07 to 3.12] for paternal suicide......BACKGROUND: Previous studies have suggested that early parental death may be associated with the emergence of bipolar disorder in later life. However, it remains unknown whether this association applies specifically to parental death due to suicide or only to early parental death. The present study...... were born in 1960 or later and were first admitted to or had first contact with Danish psychiatric facilities between 1981 and 1998 with a diagnosis of bipolar disorder, and fifty age-matched controls per case were extracted. The effects of the deaths of relatives were estimated by means...

  16. Early postoperative tumor marker responses provide a robust prognostic indicator for N3 stage gastric cancer.

    Science.gov (United States)

    Zhang, Qingrui; Qu, Hui; Sun, Guorui; Li, Zhiqiang; Ma, Shuzhen; Shi, Zhenxing; Zhao, Ensheng; Zhang, Hao; He, Qingsi

    2017-08-01

    The clinical significance of tumor markers after radical gastrectomy has not been well characterized. The purpose of this study is to evaluate the prognostic value of early postoperative tumor marker normalization in N3 stage gastric cancer (GC) patients. A total of 259 N3 stage GC patients with preoperatively elevated carcinoembryonic antigen (CEA, >5 ng/mL) or carbohydrate antigen 19-9 (CA19-9, >37 U/mL) levels underwent radical gastrectomy were analyzed retrospectively. Early postoperative tumor marker response was considered as a normalization of CEA or CA19-9 levels 4 weeks after surgery. The disease-free survival (DFS) and overall survival (OS) were analyzed. N3 stage GC patients were divided into N3a (n = 157) and N3b (n = 102) groups according to the 8th TNM stage system. Early tumor marker response was identified in 96 of 157 N3a patients (61.15%) and 57 of 102 N3b patients (55.88%). In N3 stage GC patients with a tumor marker response, significant increase was observed in both DFS (25.2 months vs 12.5 months, P tumor marker response. N3b patients with a tumor marker response showed more favorable DFS (19.2 months vs 13.6 months, P = .019) and OS (25.8 months vs 19.0 months, P = .013) compared with N3a patients lacking a tumor marker response. Multivariate analysis revealed that early tumor marker response was an independent factor for DFS and OS in N3 stage GC, as well as for depth of invasion and metastatic lymph node rate (P tumor marker levels showed poor outcomes.

  17. Bridging Computational Genetics and Vectorcardiography: A Robust Platform for the Early Detection of Heart Disease

    Science.gov (United States)

    Sridhar, S.

    2017-12-01

    By 2030, it is predicted that over 14 million people will die of heart disease annually, many of whom will discover their risk when it is too late to seek effective treatment or pursue lifestyle changes. In this research study, I sought to design a robust computational platform to gauge a patient's risk for cardiac diseases (CDs) based on demographics, genotype, and cardiac action potentials through machine learning, statistical analysis, and vectorcardiography. By analyzing previously published data, I discovered that certain polymorphisms in the ACE and MTHFR genes contribute significantly to CD risk. The deletion allele of the ACE insertion/deletion polymorphism increases ACE serum levels, promoting CD phenotypes. A point mutation in the MTHFR gene curbs the metabolism of folic acid, giving rise to CD phenotypes. I analyzed over 9000 British Medical Journal and American Heart Association patients to determine the CD risk associated with each ACE and MTHFR genotype. In the vectorcardiography phase of my study, I investigated trends in the maximal vectors of the QRS loop of the cardiac wave. Using a database with both normal and diseased vectorcardiographic action potentials, I plotted the maximal vectors on a 3D RAS coordinate plane to analyze their magnitude and direction. From the ACE datasets, I discovered that female patients over 45 and of Indian descent with two ACE deletion alleles exhibited the highest CD risk. Using this spectrum, I successfully constructed a neural network with an accuracy score of 0.867 that predicts CD risk based on ACE genotype, gender, region, and age. Investigation of the MTHFR genome showed that those with a homozygous mutated gene had a significantly higher CD risk. In my vectorcardiography study, I found that healthy QRS vectors pointed predominantly to the right-anterior region of the coordinate plane and exhibited short, consistent magnitudes. On the other hand, diseased vectors pointed to the left-posterior region and

  18. Robustness of an uncertainty and sensitivity analysis of early exposure results with the MACCS reactor accident consequence model

    International Nuclear Information System (INIS)

    Helton, J.C.; Johnson, J.D.; McKay, M.D.; Shiver, A.W.; Sprung, J.L.

    1995-01-01

    Uncertainty and sensitivity analysis techniques based on Latin hypercube sampling, partial correlation analysis and stepwise regression analysis were used in an investigation with the MACCS model of the early health effects associated with a severe accident at a nuclear power station. The following results were obtained in tests to check the robustness of the analysis techniques: two independent Latin hypercube samples produced similar uncertainty and sensitivity analysis results; setting important variables to best-estimate values produced substantial reductions in uncertainty, while setting the less important variables to best-estimate values had little effect on uncertainty; similar sensitivity analysis results were obtained when the original uniform and loguniform distributions assigned to the 34 imprecisely known input variables were changed to left-triangular distributions and then to right-triangular distributions; and analyses with rank-transformed and logarithmically-transformed data produced similar results and substantially outperformed analyses with raw (i.e., untransformed) data

  19. Lands adequation in Antioquia Department

    International Nuclear Information System (INIS)

    Arango T, Julio Cesar; Bacanumenth

    1999-01-01

    The Colombian government programs concerning land management and adequation began since the fifties. When basic frameworks for irrigating, flood control and drainage were initially developed. Several entities have made huge investments in land adequation, that lead to the improvement of national agriculture in plain regions such as Tolima, Boyaca, Magdalena and Valle del Cauca. During the same period the region of Antioquia did not benefit from the projects, mainly due to the lack of government policies concerning land adequation. Finally, in 1983 the Himat launched the small irrigation national program, which gave solutions for water management in several countryside regions of Antioquia. Twenty-nine small water districts are now operating accounting for 3.759 ha which cover 1.510 households. Now days, thanks to the presence of more accurate policies, is the right time to improve irrigation, flood control and drainage towards to a substantial improvement in the Antioquia agricultural sector, that allows it to overcome the challenges of the next millennium. A project called Antioquia nos une 1998-2000 addresses the importance of promoting the right agricultural structure that ensures agricultural mechanization for sustainability and irrigation. On the other hand, it determines the main resources needed to promote the initiative and points out the importance of distributing them in the basis of the needs and problems of the communities

  20. Robust phase-retrieval-based X-ray tomography for morphological assessment of early hepatic echinococcosis infection in rats.

    Directory of Open Access Journals (Sweden)

    Huiqiang Liu

    Full Text Available Propagation-based phase-contrast computed micro-tomography (PPCT dominates the non-destructive, three-dimensional inner-structure measurement in synchrotron-based biomedical research due to its simple experimental setup. To quantitatively visualize tiny density variations in soft tissues and organs closely related to early pathological morphology, an experimental study of synchrotron-based X-ray PPCT combined with generalized phase and attenuation duality (PAD phase retrieval was implemented with the hepatic echinococcosis (HE infection rat model at different stages. We quantitatively analyzed and evaluated the different pathological characterizations of hepatic echinococcosis during the development of this disease via our PAD-based PPCT and especially provided evidence that hepatic alveolar echinococcosis invades the liver tissue and spreads through blood flow systems with abundant blood supply in the early stage. Additionally, the infiltration of tiny vesicles in HE lesions can be clearly observed by our PAD-PPCT technique due to the striking contrast-to-noise ratio (CNR and mass density resolution, which cannot be found by the medical imaging techniques, such as magnetic resonance imaging (MRI, computed tomography (CT, and ultrasound, in hospitals. The results demonstrated that our PAD-PPCT technique has a great potential for indicating the subtle structural information of pathological changes in soft biomedical specimens, especially helpful for the research of early micro-morphology of diseases.

  1. Robust Scientists

    DEFF Research Database (Denmark)

    Gorm Hansen, Birgitte

    their core i nterests, 2) developing a selfsupply of industry interests by becoming entrepreneurs and thus creating their own compliant industry partner and 3) balancing resources within a larger collective of researchers, thus countering changes in the influx of funding caused by shifts in political...... knowledge", Danish research policy seems to have helped develop politically and economically "robust scientists". Scientific robustness is acquired by way of three strategies: 1) tasting and discriminating between resources so as to avoid funding that erodes academic profiles and push scientists away from...

  2. Maternal titers after adequate syphilotherapy during pregnancy.

    Science.gov (United States)

    Rac, Martha W F; Bryant, Stefanie N; Cantey, Joseph B; McIntire, Donald D; Wendel, George D; Sheffield, Jeanne S

    2015-03-01

    We aimed to construct a timeline for nontreponemal titer decline specific to pregnancy and evaluate factors associated with inadequate decline by delivery. This was a retrospective medical records review from September 1984 to June 2011 of women diagnosed with syphilis after 18 weeks of gestation. Women were treated according to stage of syphilis per Centers for Disease Control and Prevention guidelines. Patients with both pretreatment and delivery titers were included for data analysis. Demographics, stage of syphilis, maternal titers, delivery, and infant outcomes were recorded. Standard statistical analyses were performed for categorical and continuous data. The titer decline was analyzed using mixed-effects regression modeling. A total of 166 patients met inclusion criteria. Mean gestational age at treatment was 29.1 ± 5 weeks, and 93 (56%) women were diagnosed with early-stage syphilis. For all stages of syphilis, maternal titers declined after syphilotherapy. Pretreatment titers were higher and declined more rapidly in primary and secondary disease than in latent-stage disease and syphilis of unknown duration. Sixty-three (38%) patients achieved a 4-fold decline by delivery. Patients without a 4-fold decline by delivery were older (24.6 vs 21.5 years; P syphilis or syphilis of unknown duration, and had less time from treatment to delivery (7.8 vs 11.1 weeks; P < .001). Maternal serologic response during pregnancy after adequate syphilotherapy varied by stage of disease. Failure to achieve a 4-fold decline in titers by delivery is more a reflection of treatment timing than of treatment failure. © The Author 2014. Published by Oxford University Press on behalf of the Infectious Diseases Society of America. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com.

  3. Adequate Social Science, Curriculum Investigations, and Theory.

    Science.gov (United States)

    Anyon, Jean

    1982-01-01

    Two studies of curriculum are used as examples of trends in social science research. Criteria are developed for the "ideal" social science and then applied to the two studies. Curriculum theorizing is discussed as related to social science theory. Suggestions are made for the content of an adequate curriculum theory. (JN)

  4. Adequate supervision for children and adolescents.

    Science.gov (United States)

    Anderst, James; Moffatt, Mary

    2014-11-01

    Primary care providers (PCPs) have the opportunity to improve child health and well-being by addressing supervision issues before an injury or exposure has occurred and/or after an injury or exposure has occurred. Appropriate anticipatory guidance on supervision at well-child visits can improve supervision of children, and may prevent future harm. Adequate supervision varies based on the child's development and maturity, and the risks in the child's environment. Consideration should be given to issues as wide ranging as swimming pools, falls, dating violence, and social media. By considering the likelihood of harm and the severity of the potential harm, caregivers may provide adequate supervision by minimizing risks to the child while still allowing the child to take "small" risks as needed for healthy development. Caregivers should initially focus on direct (visual, auditory, and proximity) supervision of the young child. Gradually, supervision needs to be adjusted as the child develops, emphasizing a safe environment and safe social interactions, with graduated independence. PCPs may foster adequate supervision by providing concrete guidance to caregivers. In addition to preventing injury, supervision includes fostering a safe, stable, and nurturing relationship with every child. PCPs should be familiar with age/developmentally based supervision risks, adequate supervision based on those risks, characteristics of neglectful supervision based on age/development, and ways to encourage appropriate supervision throughout childhood. Copyright 2014, SLACK Incorporated.

  5. 29 CFR 452.110 - Adequate safeguards.

    Science.gov (United States)

    2010-07-01

    ... required to be included in the union's constitution and bylaws, but they must be observed. A labor... 29 Labor 2 2010-07-01 2010-07-01 false Adequate safeguards. 452.110 Section 452.110 Labor Regulations Relating to Labor OFFICE OF LABOR-MANAGEMENT STANDARDS, DEPARTMENT OF LABOR LABOR-MANAGEMENT...

  6. Innovating for Sustainable, Reliable and Adequate Electricity ...

    African Journals Online (AJOL)

    This research sought to determine the most readily available modes of innovation in South Africa and Nigeria to exploit both conventional and renewable energy sources, in order to generate adequate and reliable electricity as part of meeting sustainable development objectives. The research analysed a variety of ...

  7. Perception of Mothers on Adequate Nutrition

    Directory of Open Access Journals (Sweden)

    Darshini Valoo

    2017-03-01

    Full Text Available Background: Malnutrition in children less than 5 years old persists around the world. In West Java and one of the districts of West Java (Sumedang, the prevalence of malnutrition is about 18.5% and 15.8% respectively. Numerous factors can lead to child malnutrition. Difficulties in availability, accessibility, acceptability and quality of food can be contributing factors. A good perception of mother on adequate nutrition can improve children’s nutritional status. This study was conducted to study the perception of mothers with children 2 to 5 years old on adequate nutrition. Methods: Most of the respondents had good perception on the aspect of adequate nutrition. Results showed perception on availability was 83.8%, physical accessibility was 97.1%, economical accessibility was 98.6%, information accessibility was 84.8% and acceptability was 81.0%. However, perception of respondents on good quality nutrition for the main meal and additional food was still poor. Moreover, there are taboos for eating shrimp and watermelon. Additionally, children were given snacks in large amount. Results: There was a strong correlation between mid-upper arm muscle area/size and muscular strength (correlation cooefficient 0.746. Moreover, the higher the Body Mass Index, the stronger the muscle strength was to some point. If the BMI was more than 25 kg/m2, this findings did not occurred. Conclusions: This study reveals that the perception of mothers on good quality food is poor regardless the good results on availibility, accesibility and acceptability.

  8. Iron absorption from adequate Filipino meals

    International Nuclear Information System (INIS)

    Trinidad, T.P.; Madriaga, J.R.; Valdez, D.H.; Cruz, E.M.; Mallillin, A.C.; Sison, C.C.; Kuizon, M.D.

    1991-01-01

    Iron absorption from adequate Filipino meals representing the three major island groups of the Philippines (Luzon, Visayas and Mindanao) was studied using double isotope extrinsic tag method. Mean iron absorption of the one-day meal for Metro Manila was 6.6 ± 1.26%, Central Visayas, 6.3 ± 1.15% and Southern Mindanao, 6.4 ± 1.19%. Comparison between meals (breakfast, lunch, dinner) for each region as well as one-day meal for the three regions showed no significant differences (P > .01). Correlation tests done between iron absorption and the following iron enhancers: ascorbic acid, amount of fish, meat or poultry and inhibitors: phytic acid and tannic acid did not give significant results. The overall bar x of 6.4 ± 1.20% may be used as the non-heme iron absorption level from an adequate Filipino meal. This value can be considered as one of the bases for arriving at recommended dietary allowances for iron among Filipinos instead of the 10% iron absorption assumed in 1976

  9. Iron absorption from adequate Filipinos meals

    International Nuclear Information System (INIS)

    Trinidad, T.P.; Madriaga, J.R.; Valdez, D.H.; Cruz, E.M.; Mallillin, A.C.; Sison, C.C.; Kuizon, M.D.

    1989-01-01

    Iron absorption from adequate Filipino meals representing the three major island groups of the Philippines (Luzon, Visayas, and Mindanao) was studied using double isotope extrinsic tag method. Mean iron absorption of the one-day meal for Metro Manila was 6.6 +- 1.26%. Central Visayas, 6.3 +- 1.15% and Southern Mindanao, 6.4 +- 1.19%. Comparison between meals (breakfast, lunch, dinner) for each region as well as one-day meal for the three regions showed no significant differences (P>0.01). Correlation tests done between iron absorption and the following iron enhancers: ascorbic acid, amount of fish, meat or poultry; and inhibitors: phytic acid and tannic acid, did not give significant results. The overall average of 6.4 +- 1.20% may be used as the iron absorption level from an adequate Filipino meal. This value can be considered as one of the bases for arriving at recommended dietary allowances for iron among Filipinos instead of the 10% iron absorption assumed in 1976. (Auth.). 21 refs.; 3 tabs.; 3 annexes

  10. Early

    Directory of Open Access Journals (Sweden)

    Kamel Abd Elaziz Mohamed

    2014-04-01

    Conclusion: Early PDT is recommended for patients who require prolonged tracheal intubation in the ICU as outcomes like the duration of mechanical ventilation length of ICU stay and hospital stay were significantly shorter in early tracheostomy.

  11. ‘Do larger molars and robust jaws in early hominins represent dietary adaptation?’ A New Study in Tooth Wear

    Directory of Open Access Journals (Sweden)

    Anna Frances Clement

    2013-10-01

    Full Text Available Diet imposes significant constraints on the biology and behaviour of animals. The fossil record suggests that key changes in diet have taken place throughout the course of human evolution. Defining these changes enables us to understand the behaviour of our extinct fossil ancestors. Several lines of evidence are available for studying the diet of early hominins, including craniodental morphology, palaeoecology, dental microwear and stable isotopes. They do, however, often provide conflicting results. Using dental macrowear analysis, this new UCL Institute of Archaeology project will provide an alternative source of information on early hominin diet. Dental macrowear has often been used to analyse diet in archaeological populations, but this will be the first time that this type of detailed study has been applied to the early hominin fossil record.

  12. Early experience with formalin-fixed paraffin-embedded (FFPE) based commercial clinical genomic profiling of gliomas-robust and informative with caveats.

    Science.gov (United States)

    Movassaghi, Masoud; Shabihkhani, Maryam; Hojat, Seyed A; Williams, Ryan R; Chung, Lawrance K; Im, Kyuseok; Lucey, Gregory M; Wei, Bowen; Mareninov, Sergey; Wang, Michael W; Ng, Denise W; Tashjian, Randy S; Magaki, Shino; Perez-Rosendahl, Mari; Yang, Isaac; Khanlou, Negar; Vinters, Harry V; Liau, Linda M; Nghiemphu, Phioanh L; Lai, Albert; Cloughesy, Timothy F; Yong, William H

    2017-08-01

    Commercial targeted genomic profiling with next generation sequencing using formalin-fixed paraffin embedded (FFPE) tissue has recently entered into clinical use for diagnosis and for the guiding of therapy. However, there is limited independent data regarding the accuracy or robustness of commercial genomic profiling in gliomas. As part of patient care, FFPE samples of gliomas from 71 patients were submitted for targeted genomic profiling to one commonly used commercial vendor, Foundation Medicine. Genomic alterations were determined for the following grades or groups of gliomas; Grade I/II, Grade III, primary glioblastomas (GBMs), recurrent primary GBMs, and secondary GBMs. In addition, FFPE samples from the same patients were independently assessed with conventional methods such as immunohistochemistry (IHC), Quantitative real-time PCR (qRT-PCR), or Fluorescence in situ hybridization (FISH) for three genetic alterations: IDH1 mutations, EGFR amplification, and EGFRvIII expression. A total of 100 altered genes were detected by the aforementioned targeted genomic profiling assay. The number of different genomic alterations was significantly different between the five groups of gliomas and consistent with the literature. CDKN2A/B, TP53, and TERT were the most common genomic alterations seen in primary GBMs, whereas IDH1, TP53, and PIK3CA were the most common in secondary GBMs. Targeted genomic profiling demonstrated 92.3%-100% concordance with conventional methods. The targeted genomic profiling report provided an average of 5.5 drugs, and listed an average of 8.4 clinical trials for the 71 glioma patients studied but only a third of the trials were appropriate for glioma patients. In this limited comparison study, this commercial next generation sequencing based-targeted genomic profiling showed a high concordance rate with conventional methods for the 3 genetic alterations and identified mutations expected for the type of glioma. While it may not be feasible to

  13. Robust control investigations for equipment loaded panels

    DEFF Research Database (Denmark)

    Aglietti, G.S.; Langley, R.S.; Rogers, E.

    1998-01-01

    This paper develops a modelling technique for equipment load panels which directly produces (adequate) models of the underlying dynamics on which to base robust controller design/evaluations. This technique is based on the use of the Lagrange's equations of motion and the resulting models are ver...... are verified against those produced by a finite Element Method Model...

  14. Robustness of Structural Systems

    DEFF Research Database (Denmark)

    Canisius, T.D.G.; Sørensen, John Dalsgaard; Baker, J.W.

    2007-01-01

    The importance of robustness as a property of structural systems has been recognised following several structural failures, such as that at Ronan Point in 1968,where the consequenceswere deemed unacceptable relative to the initiating damage. A variety of research efforts in the past decades have ...... will be proposed. The document adopts a probabilistic risk assessment framework and includes guidance for decision-making related to robustness....... attempted to quantify aspects of robustness such as redundancy and identify design principles that can improve robustness. This paper outlines the progress of recent work by the Joint Committee on Structural Safety (JCSS) to develop comprehensive guidance on assessing and providing robustness in structural...... systems. Guidance is provided regarding the assessment of robustness in a framework that considers potential hazards to the system, vulnerability of system components, and failure consequences. Several proposed methods for quantifying robustness are reviewed, and guidelines for robust design...

  15. Robustness and Eurocodes

    NARCIS (Netherlands)

    Gulvanessian, H.; Vrouwenvelder, A.C.W.M.

    2006-01-01

    The topic of robustness is essentially covered by two Eurocodes, EN 1990: Euro-code: Basis of Structural Design [5] which provides the high level principles for achieving robustness and EN 1991-1-7 Eurocode 1: Part 1-7 Accidental Actions [6] which provides strategies and methods to obtain robustness

  16. Robustness of Structures

    DEFF Research Database (Denmark)

    Faber, Michael Havbro; Vrouwenvelder, A.C.W.M.; Sørensen, John Dalsgaard

    2011-01-01

    the development of a joint European project on structural robustness under the COST (European Cooperation in Science and Technology) programme and the decision to develop a more elaborate document on structural robustness in collaboration between experts from the JCSS and the IABSE. Accordingly, a project titled...... ‘COST TU0601: Robustness of Structures’ was initiated in February 2007, aiming to provide a platform for exchanging and promoting research in the area of structural robustness and to provide a basic framework, together with methods, strategies and guidelines enhancing robustness of structures...

  17. ENSURING ADEQUATE SAFETY WHEN USING HYDROGEN AS A FUEL

    Energy Technology Data Exchange (ETDEWEB)

    Coutts, D

    2007-01-22

    Demonstration projects using hydrogen as a fuel are becoming very common. Often these projects rely on project-specific risk evaluations to support project safety decisions. This is necessary because regulations, codes, and standards (hereafter referred to as standards) are just being developed. This paper will review some of the approaches being used in these evolving standards, and techniques which demonstration projects can implement to bridge the gap between current requirements and stakeholder desires. Many of the evolving standards for hydrogen-fuel use performance-based language, which establishes minimum performance and safety objectives, as compared with prescriptive-based language that prescribes specific design solutions. This is being done for several reasons including: (1) concern that establishing specific design solutions too early will stifle invention, (2) sparse performance data necessary to support selection of design approaches, and (3) a risk-adverse public which is unwilling to accept losses that were incurred in developing previous prescriptive design standards. The evolving standards often contain words such as: ''The manufacturer shall implement the measures and provide the information necessary to minimize the risk of endangering a person's safety or health''. This typically implies that the manufacturer or project manager must produce and document an acceptable level of risk. If accomplished using comprehensive and systematic process the demonstration project risk assessment can ease the transition to widespread commercialization. An approach to adequately evaluate and document the safety risk will be presented.

  18. Robust multivariate analysis

    CERN Document Server

    J Olive, David

    2017-01-01

    This text presents methods that are robust to the assumption of a multivariate normal distribution or methods that are robust to certain types of outliers. Instead of using exact theory based on the multivariate normal distribution, the simpler and more applicable large sample theory is given.  The text develops among the first practical robust regression and robust multivariate location and dispersion estimators backed by theory.   The robust techniques  are illustrated for methods such as principal component analysis, canonical correlation analysis, and factor analysis.  A simple way to bootstrap confidence regions is also provided. Much of the research on robust multivariate analysis in this book is being published for the first time. The text is suitable for a first course in Multivariate Statistical Analysis or a first course in Robust Statistics. This graduate text is also useful for people who are familiar with the traditional multivariate topics, but want to know more about handling data sets with...

  19. 9 CFR 305.3 - Sanitation and adequate facilities.

    Science.gov (United States)

    2010-01-01

    ... 9 Animals and Animal Products 2 2010-01-01 2010-01-01 false Sanitation and adequate facilities. 305.3 Section 305.3 Animals and Animal Products FOOD SAFETY AND INSPECTION SERVICE, DEPARTMENT OF... OF VIOLATION § 305.3 Sanitation and adequate facilities. Inspection shall not be inaugurated if an...

  20. "Something Adequate"? In Memoriam Seamus Heaney, Sister Quinlan, Nirbhaya

    Science.gov (United States)

    Parker, Jan

    2014-01-01

    Seamus Heaney talked of poetry's responsibility to represent the "bloody miracle", the "terrible beauty" of atrocity; to create "something adequate". This article asks, what is adequate to the burning and eating of a nun and the murderous gang rape and evisceration of a medical student? It considers Njabulo Ndebele's…

  1. 40 CFR 716.25 - Adequate file search.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 30 2010-07-01 2010-07-01 false Adequate file search. 716.25 Section... ACT HEALTH AND SAFETY DATA REPORTING General Provisions § 716.25 Adequate file search. The scope of a person's responsibility to search records is limited to records in the location(s) where the required...

  2. Robustness-related issues in speaker recognition

    CERN Document Server

    Zheng, Thomas Fang

    2017-01-01

    This book presents an overview of speaker recognition technologies with an emphasis on dealing with robustness issues. Firstly, the book gives an overview of speaker recognition, such as the basic system framework, categories under different criteria, performance evaluation and its development history. Secondly, with regard to robustness issues, the book presents three categories, including environment-related issues, speaker-related issues and application-oriented issues. For each category, the book describes the current hot topics, existing technologies, and potential research focuses in the future. The book is a useful reference book and self-learning guide for early researchers working in the field of robust speech recognition.

  3. Iterative robust multiprocessor scheduling

    NARCIS (Netherlands)

    Adyanthaya, S.; Geilen, M.; Basten, T.; Voeten, J.; Schiffelers, R.

    2015-01-01

    General purpose platforms are characterized by unpredictable timing behavior. Real-time schedules of tasks on general purpose platforms need to be robust against variations in task execution times. We define robustness in terms of the expected number of tasks that miss deadlines. We present an

  4. Robustness to strategic uncertainty

    NARCIS (Netherlands)

    Andersson, O.; Argenton, C.; Weibull, J.W.

    We introduce a criterion for robustness to strategic uncertainty in games with continuum strategy sets. We model a player's uncertainty about another player's strategy as an atomless probability distribution over that player's strategy set. We call a strategy profile robust to strategic uncertainty

  5. Robustness - theoretical framework

    DEFF Research Database (Denmark)

    Sørensen, John Dalsgaard; Rizzuto, Enrico; Faber, Michael H.

    2010-01-01

    not be disproportional to the causes of the damages'. However, despite the importance of robustness for structural design such requirements are not substantiated in more detail, nor have the engineering profession been able to agree on an interpretation of robustness which facilitates for its quantification. The ain...

  6. Mechanisms for Robust Cognition

    Science.gov (United States)

    Walsh, Matthew M.; Gluck, Kevin A.

    2015-01-01

    To function well in an unpredictable environment using unreliable components, a system must have a high degree of robustness. Robustness is fundamental to biological systems and is an objective in the design of engineered systems such as airplane engines and buildings. Cognitive systems, like biological and engineered systems, exist within…

  7. Robustness Recipes for Minimax Robust Optimization in Intensity Modulated Proton Therapy for Oropharyngeal Cancer Patients

    Energy Technology Data Exchange (ETDEWEB)

    Voort, Sebastian van der [Department of Radiation Oncology, Erasmus MC Cancer Institute, Rotterdam (Netherlands); Section of Nuclear Energy and Radiation Applications, Department of Radiation, Science and Technology, Delft University of Technology, Delft (Netherlands); Water, Steven van de [Department of Radiation Oncology, Erasmus MC Cancer Institute, Rotterdam (Netherlands); Perkó, Zoltán [Section of Nuclear Energy and Radiation Applications, Department of Radiation, Science and Technology, Delft University of Technology, Delft (Netherlands); Heijmen, Ben [Department of Radiation Oncology, Erasmus MC Cancer Institute, Rotterdam (Netherlands); Lathouwers, Danny [Section of Nuclear Energy and Radiation Applications, Department of Radiation, Science and Technology, Delft University of Technology, Delft (Netherlands); Hoogeman, Mischa, E-mail: m.hoogeman@erasmusmc.nl [Department of Radiation Oncology, Erasmus MC Cancer Institute, Rotterdam (Netherlands)

    2016-05-01

    Purpose: We aimed to derive a “robustness recipe” giving the range robustness (RR) and setup robustness (SR) settings (ie, the error values) that ensure adequate clinical target volume (CTV) coverage in oropharyngeal cancer patients for given gaussian distributions of systematic setup, random setup, and range errors (characterized by standard deviations of Σ, σ, and ρ, respectively) when used in minimax worst-case robust intensity modulated proton therapy (IMPT) optimization. Methods and Materials: For the analysis, contoured computed tomography (CT) scans of 9 unilateral and 9 bilateral patients were used. An IMPT plan was considered robust if, for at least 98% of the simulated fractionated treatments, 98% of the CTV received 95% or more of the prescribed dose. For fast assessment of the CTV coverage for given error distributions (ie, different values of Σ, σ, and ρ), polynomial chaos methods were used. Separate recipes were derived for the unilateral and bilateral cases using one patient from each group, and all 18 patients were included in the validation of the recipes. Results: Treatment plans for bilateral cases are intrinsically more robust than those for unilateral cases. The required RR only depends on the ρ, and SR can be fitted by second-order polynomials in Σ and σ. The formulas for the derived robustness recipes are as follows: Unilateral patients need SR = −0.15Σ{sup 2} + 0.27σ{sup 2} + 1.85Σ − 0.06σ + 1.22 and RR=3% for ρ = 1% and ρ = 2%; bilateral patients need SR = −0.07Σ{sup 2} + 0.19σ{sup 2} + 1.34Σ − 0.07σ + 1.17 and RR=3% and 4% for ρ = 1% and 2%, respectively. For the recipe validation, 2 plans were generated for each of the 18 patients corresponding to Σ = σ = 1.5 mm and ρ = 0% and 2%. Thirty-four plans had adequate CTV coverage in 98% or more of the simulated fractionated treatments; the remaining 2 had adequate coverage in 97.8% and 97.9%. Conclusions: Robustness recipes were derived that can

  8. Robustness Beamforming Algorithms

    Directory of Open Access Journals (Sweden)

    Sajad Dehghani

    2014-04-01

    Full Text Available Adaptive beamforming methods are known to degrade in the presence of steering vector and covariance matrix uncertinity. In this paper, a new approach is presented to robust adaptive minimum variance distortionless response beamforming make robust against both uncertainties in steering vector and covariance matrix. This method minimize a optimization problem that contains a quadratic objective function and a quadratic constraint. The optimization problem is nonconvex but is converted to a convex optimization problem in this paper. It is solved by the interior-point method and optimum weight vector to robust beamforming is achieved.

  9. Army General Fund Adjustments Not Adequately Documented or Supported

    Science.gov (United States)

    2016-07-26

    audit of the FY 1991 Army financial statements.6 The Army indicated in its FY 2008 Statement of Assurance on Internal Controls7 that this material...Accounting Service Indianapolis (DFAS Indianapolis) did not adequately support $2.8 trillion in third quarter journal voucher (JV) adjustments and...statements were unreliable and lacked an adequate audit trail. Furthermore, DoD and Army managers could not rely on the data in their accounting

  10. Perceptual Robust Design

    DEFF Research Database (Denmark)

    Pedersen, Søren Nygaard

    are just a few examples of cost drivers. In general, the earlier quality issues are addressed the less costs they impose. Robust design methodology seeks to anticipate many of these quality issues by making product designs less sensitive to variation. The approach was first introduced by Genichi Taguchi......The research presented in this PhD thesis has focused on a perceptual approach to robust design. The results of the research and the original contribution to knowledge is a preliminary framework for understanding, positioning, and applying perceptual robust design. Product quality is a topic...... in the 1980s and has since been expanded and refined. In more recent contributions, the notion of visual robustness has been introduced to the field of design research. However, contributions have only addressed the visual domain and no underlying theory on which to position or understand these studies have...

  11. Robust Microarray Image Processing

    OpenAIRE

    Novikov, Eugene; Barillot, Emmanuel

    2007-01-01

    In this work we have presented a complete solution for robust, high-throughput, two-color microarray image processing comprising procedures for automatic spot localization, spot quantification and spot quality control. The spot localization algorithm is fully automatic and robust with respect to deviations from perfect spot alignment and contamination. As an input, it requires only the common array design parameters: number of blocks and number of spots in the x and y directions of the array....

  12. Robust Crane Control

    OpenAIRE

    Marek Hičár; Juraj Ritók

    2006-01-01

    The paper presents robust crane design by asynchronnous motor with frequencyconvertor at ensuring system robustness against load weight and rope length variation.Exact position control and elimination of swinging in the final position are required too.Firstly were assemblied mathematical models of main crane components: crab, bridge anduplift by real model of double beamed bridge experimental crane. Was designed robustcontrol for defined interval variation of weight and rope length for real c...

  13. Robustness in econometrics

    CERN Document Server

    Sriboonchitta, Songsak; Huynh, Van-Nam

    2017-01-01

    This book presents recent research on robustness in econometrics. Robust data processing techniques – i.e., techniques that yield results minimally affected by outliers – and their applications to real-life economic and financial situations are the main focus of this book. The book also discusses applications of more traditional statistical techniques to econometric problems. Econometrics is a branch of economics that uses mathematical (especially statistical) methods to analyze economic systems, to forecast economic and financial dynamics, and to develop strategies for achieving desirable economic performance. In day-by-day data, we often encounter outliers that do not reflect the long-term economic trends, e.g., unexpected and abrupt fluctuations. As such, it is important to develop robust data processing techniques that can accommodate these fluctuations.

  14. Robust Manufacturing Control

    CERN Document Server

    2013-01-01

    This contributed volume collects research papers, presented at the CIRP Sponsored Conference Robust Manufacturing Control: Innovative and Interdisciplinary Approaches for Global Networks (RoMaC 2012, Jacobs University, Bremen, Germany, June 18th-20th 2012). These research papers present the latest developments and new ideas focusing on robust manufacturing control for global networks. Today, Global Production Networks (i.e. the nexus of interconnected material and information flows through which products and services are manufactured, assembled and distributed) are confronted with and expected to adapt to: sudden and unpredictable large-scale changes of important parameters which are occurring more and more frequently, event propagation in networks with high degree of interconnectivity which leads to unforeseen fluctuations, and non-equilibrium states which increasingly characterize daily business. These multi-scale changes deeply influence logistic target achievement and call for robust planning and control ...

  15. Robust plasmonic substrates

    DEFF Research Database (Denmark)

    Kostiučenko, Oksana; Fiutowski, Jacek; Tamulevicius, Tomas

    2014-01-01

    Robustness is a key issue for the applications of plasmonic substrates such as tip-enhanced Raman spectroscopy, surface-enhanced spectroscopies, enhanced optical biosensing, optical and optoelectronic plasmonic nanosensors and others. A novel approach for the fabrication of robust plasmonic...... substrates is presented, which relies on the coverage of gold nanostructures with diamond-like carbon (DLC) thin films of thicknesses 25, 55 and 105 nm. DLC thin films were grown by direct hydrocarbon ion beam deposition. In order to find the optimum balance between optical and mechanical properties...

  16. Robust Self Tuning Controllers

    DEFF Research Database (Denmark)

    Poulsen, Niels Kjølstad

    1985-01-01

    The present thesis concerns robustness properties of adaptive controllers. It is addressed to methods for robustifying self tuning controllers with respect to abrupt changes in the plant parameters. In the thesis an algorithm for estimating abruptly changing parameters is presented. The estimator...... has several operation modes and a detector for controlling the mode. A special self tuning controller has been developed to regulate plant with changing time delay.......The present thesis concerns robustness properties of adaptive controllers. It is addressed to methods for robustifying self tuning controllers with respect to abrupt changes in the plant parameters. In the thesis an algorithm for estimating abruptly changing parameters is presented. The estimator...

  17. 13 CFR 108.200 - Adequate capital for NMVC Companies.

    Science.gov (United States)

    2010-01-01

    ... Companies. 108.200 Section 108.200 Business Credit and Assistance SMALL BUSINESS ADMINISTRATION NEW MARKETS VENTURE CAPITAL (âNMVCâ) PROGRAM Qualifications for the NMVC Program Capitalizing A Nmvc Company § 108.200 Adequate capital for NMVC Companies. You must meet the requirements of §§ 108.200-108.230 in order to...

  18. need for adequate funding in the administration of secondary ...

    African Journals Online (AJOL)

    PROF. BARTH EKWEME

    Funding is considered all over the world as the life wire that propels the educational sector towards achieving her objectives. The paper focuses on the need for adequate funding of secondary education in Nigeria. Emphases were laid on the alternative sources of funding for secondary schools as well as the consequences ...

  19. Provision of Adequate Water Supply in Benin Province: Local ...

    African Journals Online (AJOL)

    This work examines the performance of the local governments in the provision of adequate sources of potable water in their different areas of jurisdiction in the Benin Province. The work covers the four Native Administration areas of Benin, Esan, Afemai and Asaba Divisions, which made up the Benin Province during ...

  20. Region 8: Colorado Springs Adequate Letter (8/17/2011)

    Science.gov (United States)

    This March 3, 2011 letter from EPA to Chistopher E. Urbina M.D., MPH, Colorado Department of Public Health and Environment states that EPA has found that the Colorado Springs, CO second 10 year Limited Maintenance Plan (LMP) adequate for transportation

  1. Is the Department of State Accountability Review Board Process adequate

    Science.gov (United States)

    2017-05-25

    Is the Department of State Accountability Review Board Process Adequate? A Monograph by Kenneth W. Davis Department of State School of...REPORT TYPE SAMS Monograph 3. DATES COVERED (From - To) 4. TITLE AND SUBTITLE Is the Department of State Accountability Review Board Process...

  2. 116 Appraisal as a Determinant for Adequate Compensation in ...

    African Journals Online (AJOL)

    User

    2012-01-24

    Jan 24, 2012 ... Abstract. In this paper, efforts were made to critically investigate and analyze appraisal as a determinant for adequate compensation in private sector organizations in Nigeria. Thus, the paper sets out by reviewing a body of existing literature on concept of management theories and how the subject of.

  3. Constraints to adequate provision of physical resources for the ...

    African Journals Online (AJOL)

    Constraints to adequate provision of physical resources for the universal basic education programme in delta state, Nigeria. ... The researcher used a questionnaire to collect primary data from a sample of 376 primary schools and 141 junior secondary schools head teachers across the state. Data collected were analyzed ...

  4. The Effectiveness of Clinician Education on the Adequate ...

    African Journals Online (AJOL)

    to insufficient, and/or illegible clinical information provided on laboratory request forms which may result in comments. The Effectiveness of Clinician Education on the. Adequate Completion of Laboratory Test Request. Forms at a Tertiary Hospital. Osegbe ID, Afolabi O1, Onyenekwu CP1. Department of Chemical Pathology, ...

  5. Need for Adequate Funding in the Administration of Secondary ...

    African Journals Online (AJOL)

    Funding is considered all over the world as the life wire that propels the educational sector towards achieving her objectives. The paper focuses on the need for adequate funding of secondary education in Nigeria. Emphases were laid on the alternative sources of funding for secondary schools as well as the consequences ...

  6. Robust surgery loading

    NARCIS (Netherlands)

    Hans, Elias W.; Wullink, Gerhard; van Houdenhoven, Mark; Kazemier, Geert

    2008-01-01

    We consider the robust surgery loading problem for a hospital’s operating theatre department, which concerns assigning surgeries and sufficient planned slack to operating room days. The objective is to maximize capacity utilization and minimize the risk of overtime, and thus cancelled patients. This

  7. Robustness of structures

    DEFF Research Database (Denmark)

    Vrouwenvelder, T.; Sørensen, John Dalsgaard

    2009-01-01

    robustness is still an issue of controversy and poses difficulties in regard to interpretation as well as regulation. Typically modern structural design codes require that ‘the consequence of damages to structures should not be disproportional to the causes of the damages'. However, despite the importance...

  8. Robustness of Structures

    DEFF Research Database (Denmark)

    Faber, Michael Havbro; Vrouwenvelder, A.C.W.M.; Sørensen, John Dalsgaard

    2011-01-01

    In 2005, the Joint Committee on Structural Safety (JCSS) together with Working Commission (WC) 1 of the International Association of Bridge and Structural Engineering (IABSE) organized a workshop on robustness of structures. Two important decisions resulted from this workshop, namely the developm...

  9. Robustness of spatial micronetworks

    Science.gov (United States)

    McAndrew, Thomas C.; Danforth, Christopher M.; Bagrow, James P.

    2015-04-01

    Power lines, roadways, pipelines, and other physical infrastructure are critical to modern society. These structures may be viewed as spatial networks where geographic distances play a role in the functionality and construction cost of links. Traditionally, studies of network robustness have primarily considered the connectedness of large, random networks. Yet for spatial infrastructure, physical distances must also play a role in network robustness. Understanding the robustness of small spatial networks is particularly important with the increasing interest in microgrids, i.e., small-area distributed power grids that are well suited to using renewable energy resources. We study the random failures of links in small networks where functionality depends on both spatial distance and topological connectedness. By introducing a percolation model where the failure of each link is proportional to its spatial length, we find that when failures depend on spatial distances, networks are more fragile than expected. Accounting for spatial effects in both construction and robustness is important for designing efficient microgrids and other network infrastructure.

  10. Do Online Bicycle Routing Portals Adequately Address Prevalent Safety Concerns?

    Directory of Open Access Journals (Sweden)

    Martin Loidl

    2018-03-01

    Full Text Available Safety concerns are among the most prevalent deterrents for bicycling. The provision of adequate bicycling infrastructure is considered as one of the most efficient means to increase cycling safety. However, limited public funding does not always allow agencies to implement cycling infrastructure improvements at the desirable level. Thus, bicycle trip planners can at least partly alleviate the lack of adequate infrastructure by recommending optimal routes in terms of safety. The presented study provides a systematic review of 35 bicycle routing applications and analyses to which degree they promote safe bicycling. The results show that most trip planners lack corresponding routing options and therefore do not sufficiently address safety concerns of bicyclists. Based on these findings, we developed recommendations on how to better address bicycling safety in routing portals. We suggest employing current communication technology and analysis to consider safety concerns more explicitly.

  11. Physiological aspect walking and Nordic walking as adequate kinetic activities.

    OpenAIRE

    BENEŠ, Václav

    2010-01-01

    This bachelor thesis on the topic of The Physiological Aspect of Walking and Nordic Walking as an adequate physical activity focuses on chosen physiological changes of an organism during a five-month training cycle. In the theoretical part I describe the physiological changes of organism during a regularly repeated strain, and also the technique of walking, Nordic walking and health benefits of these activities are defined here. The research part of the thesis describes the measurement method...

  12. Robust Affine Invariant Descriptors

    Directory of Open Access Journals (Sweden)

    Jianwei Yang

    2011-01-01

    Full Text Available An approach is developed for the extraction of affine invariant descriptors by cutting object into slices. Gray values associated with every pixel in each slice are summed up to construct affine invariant descriptors. As a result, these descriptors are very robust to additive noise. In order to establish slices of correspondence between an object and its affine transformed version, general contour (GC of the object is constructed by performing projection along lines with different polar angles. Consequently, affine in-variant division curves are derived. A slice is formed by points fall in the region enclosed by two adjacent division curves. To test and evaluate the proposed method, several experiments have been conducted. Experimental results show that the proposed method is very robust to noise.

  13. Robustness in Feedback Systems.

    Science.gov (United States)

    1987-06-01

    Horowitz [1%3]). A central focus of robust control theory over the years has been an attempt to generalize these results to multiinput. multioutput ... multioutput systems. These include uniformly (or li.-) optimal control (see Zames [1981]. Zames and Francis [19831. Francis and Zames [1984], and...describes a computable upper bound for multiinput multioutput two-disk problems which requires only the solution of several one-disk prob!ems. To begin

  14. Robust Airline Schedules

    OpenAIRE

    Eggenberg, Niklaus; Salani, Matteo; Bierlaire, Michel

    2010-01-01

    Due to economic pressure industries, when planning, tend to focus on optimizing the expected profit or the yield. The consequence of highly optimized solutions is an increased sensitivity to uncertainty. This generates additional "operational" costs, incurred by possible modifications of the original plan to be performed when reality does not reflect what was expected in the planning phase. The modern research trend focuses on "robustness" of solutions instead of yield or profit. Although ro...

  15. Robustness for Dummies

    OpenAIRE

    Vincenzo Verardi; Marjorie Gassner; Darwin Ugarte Ontiveros

    2012-01-01

    In the robust statistics literature, a wide variety of models have been devel- oped to cope with outliers in a rather large number of scenarios. Nevertheless, a recurrent problem for the empirical implementation of these estimators is that optimization algorithms generally do not perform well when dummy vari- ables are present. What we propose in this paper is a simple solution to this involving the replacement of the sub-sampling step of the maximization procedures by a projection-based meth...

  16. Robustness of metabolic networks

    Science.gov (United States)

    Jeong, Hawoong

    2009-03-01

    We investigated the robustness of cellular metabolism by simulating the system-level computational models, and also performed the corresponding experiments to validate our predictions. We address the cellular robustness from the ``metabolite''-framework by using the novel concept of ``flux-sum,'' which is the sum of all incoming or outgoing fluxes (they are the same under the pseudo-steady state assumption). By estimating the changes of the flux-sum under various genetic and environmental perturbations, we were able to clearly decipher the metabolic robustness; the flux-sum around an essential metabolite does not change much under various perturbations. We also identified the list of the metabolites essential to cell survival, and then ``acclimator'' metabolites that can control the cell growth were discovered. Furthermore, this concept of ``metabolite essentiality'' should be useful in developing new metabolic engineering strategies for improved production of various bioproducts and designing new drugs that can fight against multi-antibiotic resistant superbacteria by knocking-down the enzyme activities around an essential metabolite. Finally, we combined a regulatory network with the metabolic network to investigate its effect on dynamic properties of cellular metabolism.

  17. The Crane Robust Control

    Directory of Open Access Journals (Sweden)

    Marek Hicar

    2004-01-01

    Full Text Available The article is about a control design for complete structure of the crane: crab, bridge and crane uplift.The most important unknown parameters for simulations are burden weight and length of hanging rope. We will use robustcontrol for crab and bridge control to ensure adaptivity for burden weight and rope length. Robust control will be designed for current control of the crab and bridge, necessary is to know the range of unknown parameters. Whole robust will be splitto subintervals and after correct identification of unknown parameters the most suitable robust controllers will be chosen.The most important condition at the crab and bridge motion is avoiding from burden swinging in the final position. Crab and bridge drive is designed by asynchronous motor fed from frequency converter. We will use crane uplift with burden weightobserver in combination for uplift, crab and bridge drive with cooperation of their parameters: burden weight, rope length and crab and bridge position. Controllers are designed by state control method. We will use preferably a disturbance observerwhich will identify burden weight as a disturbance. The system will be working in both modes at empty hook as well asat maximum load: burden uplifting and dropping down.

  18. Children with Disabilities Are Often Misdiagnosed Initially and Children with Neuropsychiatric Disorders Are Referred to Adequate Resources 30 Months Later than Children with Other Disabilities

    Science.gov (United States)

    Tuominen-Eriksson, Alli-Marie; Svensson, Yvonne; Gunnarsson, Ronny K.

    2013-01-01

    Disabilities in a child may lead to low self-esteem and social problems. The lives of parents and siblings are also affected. Early intervention may decrease these consequences. To promote early intervention early referral to adequate resources is essential. In a longitudinal retrospective observational study it was found that children with…

  19. A student's perspective: are medical students adequately trained in BLS?

    Directory of Open Access Journals (Sweden)

    Oyewole T

    2016-11-01

    Full Text Available Tobi Oyewole,1 Folashade Oyewole2 1University of Liverpool – The School of Medicine, Liverpool, 2Imperial College London, London, UK We read with great interest the article by Lami et al regarding improving basic life support (BLS training for medical students.1 We agree that BLS skills are vital for junior doctors. The days of trial by fire have long gone away, and junior doctors and medical students need to feel that they are adequately trained to handle emergency situations they may face in hospital.  Read the original article

  20. The importance of robust design methodology

    DEFF Research Database (Denmark)

    Eifler, Tobias; Howard, Thomas J.

    2018-01-01

    of unanticipated variation effects remain largely underestimated and thus unaccounted for in design practice, sometimes with disastrous consequences. To foster the awareness of this variation and to illustrate the benefits of its early consideration in product development, this paper reviews one of the most...... to illustrate how already simple analyses and early stage design methods can help to better understand one of the potential reasons for these failures, namely the variation inherent in manufacturing, assembly, and use processes. Usually thoroughly controlled in production, it seems as if particularly the risk...... infamous recalls in automotive history, that of the GM ignition switch, from the perspective of Robust Design. It is investigated if available Robust Design methods such as sensitivity analysis, tolerance stack-ups, design clarity, etc. would have been suitable to account for the performance variation...

  1. Barriers to adequate prenatal care utilization in American Samoa

    Science.gov (United States)

    Hawley, Nicola L; Brown, Carolyn; Nu’usolia, Ofeira; Ah-Ching, John; Muasau-Howard, Bethel; McGarvey, Stephen T

    2013-01-01

    Objective To describe the utilization of prenatal care in American Samoan women and to identify socio-demographic predictors of inadequate prenatal care utilization. Methods Using data from prenatal clinic records, women (n=692) were categorized according to the Adequacy of Prenatal Care Utilization Index as having received adequate plus, adequate, intermediate or inadequate prenatal care during their pregnancy. Categorical socio-demographic predictors of the timing of initiation of prenatal care (week of gestation) and the adequacy of received services were identified using one way Analysis of Variance (ANOVA) and independent samples t-tests. Results Between 2001 and 2008 85.4% of women received inadequate prenatal care. Parity (P=0.02), maternal unemployment (P=0.03), and both parents being unemployed (P=0.03) were negatively associated with the timing of prenatal care initation. Giving birth in 2007–2008, after a prenatal care incentive scheme had been introduced in the major hospital, was associated with earlier initiation of prenatal care (20.75 versus 25.12 weeks; Pprenatal care utilization in American Samoa is a major concern. Improving healthcare accessibility will be key in encouraging women to attend prenatal care. The significant improvements in the adequacy of prenatal care seen in 2007–2008 suggest that the prenatal care incentive program implemented in 2006 may be a very positive step toward addressing issues of prenatal care utilization in this population. PMID:24045912

  2. Quantifying dose to the reconstructed breast: Can we adequately treat?

    Energy Technology Data Exchange (ETDEWEB)

    Chung, Eugene; Marsh, Robin B.; Griffith, Kent A.; Moran, Jean M. [Department of Radiation Oncology, University of Michigan, Ann Arbor, MI (United States); Pierce, Lori J., E-mail: ljpierce@umich.edu [Department of Radiation Oncology, University of Michigan, Ann Arbor, MI (United States)

    2013-04-01

    To evaluate how immediate reconstruction (IR) impacts postmastectomy radiotherapy (PMRT) dose distributions to the reconstructed breast (RB), internal mammary nodes (IMN), heart, and lungs using quantifiable dosimetric end points. 3D conformal plans were developed for 20 IR patients, 10 autologous reconstruction (AR), and 10 expander-implant (EI) reconstruction. For each reconstruction type, 5 right- and 5 left-sided reconstructions were selected. Two plans were created for each patient, 1 with RB coverage alone and 1 with RB + IMN coverage. Left-sided EI plans without IMN coverage had higher heart Dmean than left-sided AR plans (2.97 and 0.84 Gy, p = 0.03). Otherwise, results did not vary by reconstruction type and all remaining metrics were evaluated using a combined AR and EI dataset. RB coverage was adequate regardless of laterality or IMN coverage (Dmean 50.61 Gy, D95 45.76 Gy). When included, IMN Dmean and D95 were 49.57 and 40.96 Gy, respectively. Mean heart doses increased with left-sided treatment plans and IMN inclusion. Right-sided treatment plans and IMN inclusion increased mean lung V{sub 20}. Using standard field arrangements and 3D planning, we observed excellent coverage of the RB and IMN, regardless of laterality or reconstruction type. Our results demonstrate that adequate doses can be delivered to the RB with or without IMN coverage.

  3. [The human right to adequate food: an urban vision].

    Science.gov (United States)

    Casemiro, Juliana Pereira; Valla, Victor Vincent; Guimarães, Maria Beatriz Lisboa

    2010-07-01

    The human right to adequate food is comprehended in two dimensions: being free of hunger and denutrition and having access to an adequate food. The urban context, in which the possession of food is done primarily through merchandising because of its strong consuming appealing, became a big challenge to debate this topic in poor districts today. Here we combine considerations of a qualitative study carried out in São João de Meriti, Rio de Janeiro State, joining leaders from Pastoral da Criança in focal group sessions. The unemployment, the sub-employment and the difficulty in reaching the public health system, the social assistance and basic sanitation were presented as the major obstacles to bring into effect the human right to food. It was possible to determine that, among the strategies to fight the poverty and hunger, a big highlight is the establishment of mutual help mechanisms. The social support, generosity and religiousness were presented as the most important categories among the thoughts of the leaders. Facing a reality in which poverty and hunger appear as something inherent or become a mechanism of change during elections, the issue of the clienteles appears as a huge concern and challenge for those leaders.

  4. Quantifying dose to the reconstructed breast: Can we adequately treat?

    International Nuclear Information System (INIS)

    Chung, Eugene; Marsh, Robin B.; Griffith, Kent A.; Moran, Jean M.; Pierce, Lori J.

    2013-01-01

    To evaluate how immediate reconstruction (IR) impacts postmastectomy radiotherapy (PMRT) dose distributions to the reconstructed breast (RB), internal mammary nodes (IMN), heart, and lungs using quantifiable dosimetric end points. 3D conformal plans were developed for 20 IR patients, 10 autologous reconstruction (AR), and 10 expander-implant (EI) reconstruction. For each reconstruction type, 5 right- and 5 left-sided reconstructions were selected. Two plans were created for each patient, 1 with RB coverage alone and 1 with RB + IMN coverage. Left-sided EI plans without IMN coverage had higher heart Dmean than left-sided AR plans (2.97 and 0.84 Gy, p = 0.03). Otherwise, results did not vary by reconstruction type and all remaining metrics were evaluated using a combined AR and EI dataset. RB coverage was adequate regardless of laterality or IMN coverage (Dmean 50.61 Gy, D95 45.76 Gy). When included, IMN Dmean and D95 were 49.57 and 40.96 Gy, respectively. Mean heart doses increased with left-sided treatment plans and IMN inclusion. Right-sided treatment plans and IMN inclusion increased mean lung V 20 . Using standard field arrangements and 3D planning, we observed excellent coverage of the RB and IMN, regardless of laterality or reconstruction type. Our results demonstrate that adequate doses can be delivered to the RB with or without IMN coverage

  5. Is prophetic discourse adequate to address global economic justice?

    Directory of Open Access Journals (Sweden)

    Piet J. Naudé

    2011-04-01

    Full Text Available This article outlined key features of prophetic discourse and investigated whether this form of moral discourse adequately addresses issues of economic injustice. It is shown that the strength of prophetic discourse is its ability to denounce instances of injustice whilst at the same time announcing a God-willed alternative future. The ‘preferential option for the poor’ in Latin American liberation theologies is treated as a case study of the influence of prophetic discourse in contexts of perceived economic injustice. Also the core weaknesses of prophetic discourse are investigated, specifically its incomplete moral argument, weak moral analyses, silence on transition measures, and its inability to take a positive stance on reforms in the system from which itself benefits. In the final section it is concluded that prophetic discourse plays an indispensable role in addressing issues of global economic justice, but – taken by itself – it is not an adequate form of moral discourse to address concrete matters of justice.

  6. Adequate sizing and motor exploitation: Motor energy management

    Directory of Open Access Journals (Sweden)

    Kostić Miloje M.

    2011-01-01

    Full Text Available Motor energy management includes adequate sizing, control and improvement of electric energy quality, i.e. voltage quality (reducing voltage unbalance and harmonics distortion, and the proper maintenance. The specific motor price per kW is approximately constant for motors rated from 5 kW to 20 kW. By adequate sizing, or by proper replacement of the old motor with the new one, with rated output power reduced by 20% to 50% the smaller motor will be also cheaper by 20% to 50%. When the 22 kW motor is replaced with the new 15 kW that costs 64% of the price of a new 22 kW motor, the efficiency is increased by 3.6% (Example in paper. On the basis of our investigation results, it is confirmed that there are significant possibilities for energy savings by setting voltage values within the ±5% voltage band (Un±5%, since more than 80% induction motors are under loaded (£70%, especially small and medium rated power (1-30 kW motors.

  7. Robust efficient video fingerprinting

    Science.gov (United States)

    Puri, Manika; Lubin, Jeffrey

    2009-02-01

    We have developed a video fingerprinting system with robustness and efficiency as the primary and secondary design criteria. In extensive testing, the system has shown robustness to cropping, letter-boxing, sub-titling, blur, drastic compression, frame rate changes, size changes and color changes, as well as to the geometric distortions often associated with camcorder capture in cinema settings. Efficiency is afforded by a novel two-stage detection process in which a fast matching process first computes a number of likely candidates, which are then passed to a second slower process that computes the overall best match with minimal false alarm probability. One key component of the algorithm is a maximally stable volume computation - a three-dimensional generalization of maximally stable extremal regions - that provides a content-centric coordinate system for subsequent hash function computation, independent of any affine transformation or extensive cropping. Other key features include an efficient bin-based polling strategy for initial candidate selection, and a final SIFT feature-based computation for final verification. We describe the algorithm and its performance, and then discuss additional modifications that can provide further improvement to efficiency and accuracy.

  8. Robust Cultural Pluralism

    Directory of Open Access Journals (Sweden)

    Richard A. Shweder

    2013-11-01

    Full Text Available In this wide ranging interview, Professor Richard A. Shweder from the Department of Comparative Human Development at the University of Chicago, discusses whether it is or is not possible to be a robust cultural pluralist and a dedicated political liberal at the same time. In this discussion, Professor Shweder offers his insights - based on over 40 years of research - on issues related to the history and re-emergence of cultural psychology; moral anthropology and psychology; the experimental method in psychological investigation and its philosophical basis; contemporary and historical cultural collisions – most notably conflicting representations of female genital surgeries; cultural diversity and inequality; and the dissemination of ideas through open access publishing and Twitter. Professor Shweder ends by offering valuable advice to young researchers in the field of cultural psychology as well as a glimpse into the larger themes of his forthcoming book, which seeks to provide answers to the question of what forms of political liberalism are most compatible with robust cultural pluralism and which are not.

  9. Robustness Metrics: Consolidating the multiple approaches to quantify Robustness

    DEFF Research Database (Denmark)

    Göhler, Simon Moritz; Eifler, Tobias; Howard, Thomas J.

    2016-01-01

    determined to be conceptually different from one another. The metrics were classified by their meaning and interpretation based on the types of information necessary to calculate the metrics. Four different classes were identified: 1) Sensitivity robustness metrics; 2) Size of feasible design space......, this ambiguity can have significant influence on the strategies used to combat variability, the way it is quantified and ultimately, the quality of the final design. In this contribution the literature for robustness metrics was systematically reviewed. From the 108 relevant publications found, 38 metrics were...... robustness metrics; 3) Functional expectancy and dispersion robustness metrics; and 4) Probability of conformance robustness metrics. The goal was to give a comprehensive overview of robustness metrics and guidance to scholars and practitioners to understand the different types of robustness metrics...

  10. Standards for securing adequate indoor air quality across Europe

    DEFF Research Database (Denmark)

    Wargocki, Pawel; Carrer, P.; de Oliveira Fernandes, E.

    2013-01-01

    effects of IAQ into different components: exposures to indoor and outdoor air pollutants, association with different morbidities and the way ventilation based approaches could minimise their impact. Disability adjusted life years (DALYs), a common metric to allow comparability of impacts on various types...... and is determined mainly considering the metabolic CO2 production. It is only applicable if all other pollutants meet WHO guidelines for ambient and indoor air quality. If they do not meet these guidelines after applying source control and when air used for ventilation is clean health-based ventilation rate should...... be a multiple of the minimum rate. Conclusions: Optimal strategy for ensuring adequate IAQ to ensure health conditions must include cleaning of ambient air (if necessary) and source control; only then health-based ventilation rate can be defined. Such approach is expected to half the BOD caused by indoor...

  11. Nuclear waste disposal: achieving adequate financing - special study

    International Nuclear Information System (INIS)

    Quasebarth, M.V.

    1984-01-01

    An analysis by the Congressional Budget Office (CBO) evaluates whether the current one mill fee now charged to nuclear-electricity consumers will adequately finance the waste disposal program. The CBO found that, if the fee is adjusted annually for inflation, it should provide enough revenues to cover all program costs under all nuclear growth forecasts. If the fee is unchanged, however, the fees will be inadequate if inflation exceeds 3% annually. The report suggests two alternatives for fee revision, but makes no recommendations. The alternatives are to increase the fee only at specific intervals or to automatically adjust the fee through indexation. The report examines the effect of delaying the program, cost overruns, and alternative inflation rate and interest rate assumptions. 3 figures, 12 tables

  12. International Conference on Robust Statistics

    CERN Document Server

    Filzmoser, Peter; Gather, Ursula; Rousseeuw, Peter

    2003-01-01

    Aspects of Robust Statistics are important in many areas. Based on the International Conference on Robust Statistics 2001 (ICORS 2001) in Vorau, Austria, this volume discusses future directions of the discipline, bringing together leading scientists, experienced researchers and practitioners, as well as younger researchers. The papers cover a multitude of different aspects of Robust Statistics. For instance, the fundamental problem of data summary (weights of evidence) is considered and its robustness properties are studied. Further theoretical subjects include e.g.: robust methods for skewness, time series, longitudinal data, multivariate methods, and tests. Some papers deal with computational aspects and algorithms. Finally, the aspects of application and programming tools complete the volume.

  13. Robust procedures in chemometrics

    DEFF Research Database (Denmark)

    Kotwa, Ewelina

    -way chemometrical methods, such as PCA and PARAFAC models for analysing spatial and depth profiles of sea water samples, defined by three data modes: depth, variables and geographical location. Emphasis was also put on predicting fluorescence values, as being a natural measure of biological activity, by applying...... if contamination in the data is present. For this becoming a standard procedure, further work is required, aiming at implementing reliable robust algorithms into standard statistical programs.......The general aim of the thesis was to contribute to the improvement of data analytical techniques within the chemometric field. Regardless the multivariate structure of the data, it is still common in some fields to perform uni-variate data analysis using only simple statistics such as sample mean...

  14. Robust automated knowledge capture.

    Energy Technology Data Exchange (ETDEWEB)

    Stevens-Adams, Susan Marie; Abbott, Robert G.; Forsythe, James Chris; Trumbo, Michael Christopher Stefan; Haass, Michael Joseph; Hendrickson, Stacey M. Langfitt

    2011-10-01

    This report summarizes research conducted through the Sandia National Laboratories Robust Automated Knowledge Capture Laboratory Directed Research and Development project. The objective of this project was to advance scientific understanding of the influence of individual cognitive attributes on decision making. The project has developed a quantitative model known as RumRunner that has proven effective in predicting the propensity of an individual to shift strategies on the basis of task and experience related parameters. Three separate studies are described which have validated the basic RumRunner model. This work provides a basis for better understanding human decision making in high consequent national security applications, and in particular, the individual characteristics that underlie adaptive thinking.

  15. Robust Optical Flow Estimation

    Directory of Open Access Journals (Sweden)

    Javier Sánchez Pérez

    2013-10-01

    Full Text Available n this work, we describe an implementation of the variational method proposed by Brox etal. in 2004, which yields accurate optical flows with low running times. It has several benefitswith respect to the method of Horn and Schunck: it is more robust to the presence of outliers,produces piecewise-smooth flow fields and can cope with constant brightness changes. Thismethod relies on the brightness and gradient constancy assumptions, using the information ofthe image intensities and the image gradients to find correspondences. It also generalizes theuse of continuous L1 functionals, which help mitigate the effect of outliers and create a TotalVariation (TV regularization. Additionally, it introduces a simple temporal regularizationscheme that enforces a continuous temporal coherence of the flow fields.

  16. Robust snapshot interferometric spectropolarimetry.

    Science.gov (United States)

    Kim, Daesuk; Seo, Yoonho; Yoon, Yonghee; Dembele, Vamara; Yoon, Jae Woong; Lee, Kyu Jin; Magnusson, Robert

    2016-05-15

    This Letter describes a Stokes vector measurement method based on a snapshot interferometric common-path spectropolarimeter. The proposed scheme, which employs an interferometric polarization-modulation module, can extract the spectral polarimetric parameters Ψ(k) and Δ(k) of a transmissive anisotropic object by which an accurate Stokes vector can be calculated in the spectral domain. It is inherently strongly robust to the object 3D pose variation, since it is designed distinctly so that the measured object can be placed outside of the interferometric module. Experiments are conducted to verify the feasibility of the proposed system. The proposed snapshot scheme enables us to extract the spectral Stokes vector of a transmissive anisotropic object within tens of msec with high accuracy.

  17. The efficacy of support vector machines (SVM) in robust ...

    Indian Academy of Sciences (India)

    The efficacy of support vector machines (SVM) in robust determination of earthquake early ... This work deals with a methodology applied to seismic early warning systems which are designed to provide real-time estimation of the ... The effectiveness of warning systems can be pre- dicted by using P-wave rather than S-wave ...

  18. Identification of children with reading difficulties: Cheap can be adequate

    DEFF Research Database (Denmark)

    Poulsen, Mads; Nielsen, Anne-Mette Veber

    Classification of reading difficulties: Cheap screening can be accurate Purpose: Three factors are important for identification of students in need of remedial instruction: accuracy, timeliness, and cost. The identification has to be accurate to be of any use, the identification has to be timely......, inexpensive testing. The present study investigated the classification accuracy of three screening models varying in timeliness and cost. Method: We compared the ROC statistics of three logistic models for predicting end of Grade 2 reading difficulties in a sample of 164 students: 1) an early, comprehensive...... to allow for optimal remediation, and the procedure should preferably be inexpensive to allow wide-spread adoption. These criteria are, however, often in conflict: Early screening may be less accurate than late screening, and comprehensive and expensive testing is possibly more accurate than simple...

  19. Robust Schur Stability and Robust H^2 Performance

    DEFF Research Database (Denmark)

    Stoustrup, Jakob; Zhao, K.-Y.

    1996-01-01

    In this paper we address the problems of robust stability androbust QTR H^2 performance for uncertain discrete time systemswith nonlinear parametric uncertainties. We consider two families ofsystems with parametric uncertainties described by state space modelswhich offer a fairly general...... providea line search algorithm for the these two problems in case of two parameters.Both for the robust stability and the robust performance probelm, explicitnecessary and sufficient conditions are derived. An illustrative exampledemonstrates the algorithms....

  20. Are Vancomycin Trough Concentrations Adequate for Optimal Dosing?

    Science.gov (United States)

    Youn, Gilmer; Jones, Brenda; Jelliffe, Roger W.; Drusano, George L.; Rodvold, Keith A.; Lodise, Thomas P.

    2014-01-01

    The current vancomycin therapeutic guidelines recommend the use of only trough concentrations to manage the dosing of adults with Staphylococcus aureus infections. Both vancomycin efficacy and toxicity are likely to be related to the area under the plasma concentration-time curve (AUC). We assembled richly sampled vancomycin pharmacokinetic data from three studies comprising 47 adults with various levels of renal function. With Pmetrics, the nonparametric population modeling package for R, we compared AUCs estimated from models derived from trough-only and peak-trough depleted versions of the full data set and characterized the relationship between the vancomycin trough concentration and AUC. The trough-only and peak-trough depleted data sets underestimated the true AUCs compared to the full model by a mean (95% confidence interval) of 23% (11 to 33%; P = 0.0001) and 14% (7 to 19%; P vancomycin MIC is 1 mg/liter, approximately 60% are expected to have a trough concentration below the suggested minimum target of 15 mg/liter for serious infections, which could result in needlessly increased doses and a risk of toxicity. Our data indicate that adjustment of vancomycin doses on the basis of trough concentrations without a Bayesian tool results in poor achievement of maximally safe and effective drug exposures in plasma and that many adults can have an adequate vancomycin AUC with a trough concentration of <15 mg/liter. PMID:24165176

  1. Deferasirox pharmacokinetics in patients with adequate versus inadequate response

    Science.gov (United States)

    Chirnomas, Deborah; Smith, Amber Lynn; Braunstein, Jennifer; Finkelstein, Yaron; Pereira, Luis; Bergmann, Anke K.; Grant, Frederick D.; Paley, Carole; Shannon, Michael

    2009-01-01

    Tens of thousands of transfusion-dependent (eg, thalassemia) patients worldwide suffer from chronic iron overload and its potentially fatal complications. The oral iron chelator deferasirox has become commercially available in many countries since 2006. Although this alternative to parenteral deferoxamine has been a major advance for patients with transfusional hemosiderosis, a proportion of patients have suboptimal response to the maximum approved doses (30 mg/kg per day), and do not achieve negative iron balance. We performed a prospective study of oral deferasirox pharmacokinetics (PK), comparing 10 transfused patients with inadequate deferasirox response (rising ferritin trend or rising liver iron on deferasirox doses > 30 mg/kg per day) with control transfusion-dependent patients (n = 5) with adequate response. Subjects were admitted for 4 assessments: deferoxamine infusion and urinary iron measurement to assess readily chelatable iron; quantitative hepatobiliary scintigraphy to assess hepatic uptake and excretion of chelate; a 24-hour deferasirox PK study following a single 35-mg/kg dose of oral deferasirox; and pharmacogenomic analysis. Patients with inadequate response to deferasirox had significantly lower systemic drug exposure compared with control patients (P deferasirox must be determined. This trial has been registered at http://www.clinicaltrials.gov under identifier NCT00749515. PMID:19724055

  2. Assessing vitamin D nutritional status: Is capillary blood adequate?

    Science.gov (United States)

    Jensen, M E; Ducharme, F M; Théorêt, Y; Bélanger, A-S; Delvin, E

    2016-06-01

    Venous blood is the usual sample for measuring various biomarkers, including 25-hydroxyvitamin D (25OHD). However, it can prove challenging in infants and young children. Hence the finger-prick capillary collection is an alternative, being a relatively simple procedure perceived to be less invasive. We elected to validate the use of capillary blood sampling for 25OHD quantification by liquid chromatography tandem-mass spectrometry (LC/MS-MS). Venous and capillary blood samples were simultaneously collected from 15 preschool-aged children with asthma 10days after receiving 100,000IU of vitamin-D3 or placebo and 20 apparently healthy adult volunteers. 25OHD was measured by an in-house LC/MS-MS method. The venous 25OHD values varied between 23 and 255nmol/l. The venous and capillary blood total 25OHD concentrations highly correlated (r(2)=0.9963). The mean difference (bias) of capillary blood 25OHD compared to venous blood was 2.0 (95% CI: -7.5, 11.5) nmol/l. Our study demonstrates excellent agreement with no evidence of a clinically important bias between venous and capillary serum 25OHD concentrations measured by LC/MS-MS over a wide range of values. Under those conditions, capillary blood is therefore adequate for the measurement of 25OHD. Copyright © 2016 Elsevier B.V. All rights reserved.

  3. Robust cognitive change.

    Science.gov (United States)

    Salthouse, Timothy A

    2012-07-01

    Two major challenges facing researchers interested in cognitive change are that measures of change are often not very reliable, and they may reflect effects of prior test experience in addition to the factors of primary interest. One approach to dealing with these problems is to obtain multiple measures of change on parallel versions of the same tests in a measurement burst design. A total of 783 adults performed three parallel versions of cognitive tests on two occasions separated by an average of 2.6 years. Performance increased substantially across the three sessions within each occasion, and for all but vocabulary ability these within-occasion improvements were considerably larger than the between-occasion changes. Reliabilities of the changes in composite scores were low, but averages of the three changes had larger, albeit still quite modest, reliabilities. In some cognitive abilities individual differences were evident in the relation of prior test experience and the magnitude of longitudinal change. Although multiple assessments are more time consuming than traditional measurement procedures, the resulting estimates of change are more robust than those from conventional methods, and also allow the influence of practice on change to be systematically investigated.

  4. Robust continuous clustering.

    Science.gov (United States)

    Shah, Sohil Atul; Koltun, Vladlen

    2017-09-12

    Clustering is a fundamental procedure in the analysis of scientific data. It is used ubiquitously across the sciences. Despite decades of research, existing clustering algorithms have limited effectiveness in high dimensions and often require tuning parameters for different domains and datasets. We present a clustering algorithm that achieves high accuracy across multiple domains and scales efficiently to high dimensions and large datasets. The presented algorithm optimizes a smooth continuous objective, which is based on robust statistics and allows heavily mixed clusters to be untangled. The continuous nature of the objective also allows clustering to be integrated as a module in end-to-end feature learning pipelines. We demonstrate this by extending the algorithm to perform joint clustering and dimensionality reduction by efficiently optimizing a continuous global objective. The presented approach is evaluated on large datasets of faces, hand-written digits, objects, newswire articles, sensor readings from the Space Shuttle, and protein expression levels. Our method achieves high accuracy across all datasets, outperforming the best prior algorithm by a factor of 3 in average rank.

  5. Are we telling the diabetic patients adequately about foot care

    International Nuclear Information System (INIS)

    Ali, R.; Din, M.J.U.; Jadoon, R.J.; Farooq, U.; Alam, M.A.; Qureshi, A.; Shah, S.U.

    2016-01-01

    Background: Diabetes mellitus affects more than 285 million people worldwide. The prevalence is expected to rise to 439 million by the year 2030. Diabetic foot ulcers precede 84 percentage of non-traumatic amputations in diabetics. One lower limb is lost every 30 seconds around the world because of diabetic foot ulceration. Apart from being lengthy, the treatment of diabetic foot is also very expensive. There is very limited emphasis on foot care in diabetic patients. Even in developed countries patients feel that they do not have adequate knowledge about foot care. This study was conducted to find out how much information is imparted by doctors to diabetic patients about foot care. Methods: This cross-sectional study was conducted in admitted patients of the Department of Medicine, DHQ Hospital, Abbottabad from May 2014 to June 2015. 139 diabetic patients more than 25 years of age were included by non-probability consecutive sampling. Results: The mean age was 57.17 ( percentage 11.1) years. 35.3 percentage of patients were male and 64.7 percentage were female. The mean duration of diabetes in patients was 8.3 (±6) years. Only 36.7 percentage of patients said that their doctor told them about foot care. Less than 40 percentage of patients knew that they should daily inspect their feet, wash them with gentle warm water, and dry them afterwards. Only 25.2 percentage of the participants knew how to manage corns or calluses on feet. 66.5 percentage of patients knew that they should not walk bare foot. Overall, 63 percentage of our patients had less than 50 percentage knowledge of the 11 points regarding foot care that the investigators asked them. Conclusion: Diabetic foot problems are the one of the costliest, most disabling and disheartening complication of diabetes mellitus. Doctors are not properly telling diabetic patients about foot care. There is a deficiency of knowledge among the diabetic patients regarding foot care. (author)

  6. Improving access to adequate pain management in Taiwan.

    Science.gov (United States)

    Scholten, Willem

    2015-06-01

    There is a global crisis in access to pain management in the world. WHO estimates that 4.65 billion people live in countries where medical opioid consumption is near to zero. For 2010, WHO considered a per capita consumption of 216.7 mg morphine equivalents adequate, while Taiwan had a per capita consumption of 0.05 mg morphine equivalents in 2007. In Asia, the use of opioids is sensitive because of the Opium Wars in the 19th century and for this reason, the focus of controlled substances policies has been on the prevention of diversion and dependence. However, an optimal public health outcome requires that also the beneficial aspects of these substances are acknowledged. Therefore, WHO recommends a policy based on the Principle of Balance: ensuring access for medical and scientific purposes while preventing diversion, harmful use and dependence. Furthermore, international law requires that countries ensure access to opioid analgesics for medical and scientific purposes. There is evidence that opioid analgesics for chronic pain are not associated with a major risk for developing dependence. Barriers for access can be classified in the categories of overly restrictive laws and regulations; insufficient medical training on pain management and problems related to assessment of medical needs; attitudes like an excessive fear for dependence or diversion; and economic and logistical problems. The GOPI project found many examples of such barriers in Asia. Access to opioid medicines in Taiwan can be improved by analysing the national situation and drafting a plan. The WHO policy guidelines Ensuring Balance in National Policies on Controlled Substances can be helpful for achieving this purpose, as well as international guidelines for pain treatment. Copyright © 2015. Published by Elsevier B.V.

  7. Are minidisc recorders adequate for the study of respiratory sounds?

    Science.gov (United States)

    Kraman, Steve S; Wodicka, George R; Kiyokawa, Hiroshi; Pasterkamp, Hans

    2002-01-01

    Digital audio tape (DAT) recorders have become the de facto gold standard recording devices for lung sounds. Sound recorded on DAT is compact-disk (CD) quality with adequate sensitivity from below 20 Hz to above 20 KHz. However, DAT recorders have drawbacks. Although small, they are relatively heavy, the recording mechanism is complex and delicate, and finding one desired track out of many is inconvenient. A more recent development in portable recording devices is the minidisc (MD) recorder. These recorders are widely available, inexpensive, small and light, rugged, mechanically simple, and record digital data in tracks that may be named and accessed directly. Minidiscs hold as much recorded sound as a compact disk but in about 1/5 of the recordable area. The data compression is achieved by use of a technique known as adaptive transform acoustic coding for minidisc (ATRAC). This coding technique makes decisions about what components of the sound would not be heard by a human listener and discards the digital information that represents these sounds. Most of this compression takes place on sounds above 5.5 KHz. As the intended use of these recorders is the storage and reproduction of music, it is unknown whether ATRAC will discard or distort significant portions of typical lung sound signals. We determined the suitability of MD recorders for respiratory sound research by comparing a variety of normal and pathologic lung sounds that were digitized directly into a computer and also after recording by a DAT recorder and 2 different MD recorders (Sharp and Sony). We found that the frequency spectra and waveforms of respiratory sounds were not distorted in any important way by recording on the two MD recorders tested.

  8. Adequately Addressing Pediatric Obesity: Challenges Faced by Primary Care Providers.

    Science.gov (United States)

    Shreve, Marilou; Scott, Allison; Vowell Johnson, Kelly

    2017-07-01

    To assess the challenges primary care providers encounter when providing counseling for pediatric patients identified as obese. A survey assessed the current challenges and barriers to the screening and treatment of pediatric obesity for providers in northwest Arkansas who provide care to families. The survey consisted of 15 Likert scale questions and 4 open-ended questions. Time, resources, comfort, and cultural issues were reported by providers as the biggest barriers in screening and the treatment of pediatric obesity. All providers reported lack of time as a barrier to providing the care needed for obese children. Cultural barriers of both the provider and client were identified as factors, which negatively affect the care and treatment of obese children. Primary care providers continue to experience challenges when addressing pediatric obesity. In this study, a lack of adequate time to address obesity was identified as the most significant current barrier and may likely be tied to physician resources. Although reimbursement for obesity is increasing, the level of reimbursement does not support the time or the resources needed to treat patients. Many providers reported their patients' cultural view of obesity influenced how they counsel their patients. Increasing providers' knowledge concerning differences in how weight is viewed or valued may assist them in the assessment and care of obese pediatric patients. The challenges identified in previous research continue to limit providers when addressing obesity. Although progress has been made regarding knowledge of guidelines, continuing effort is needed to tackle the remaining challenges. This will allow for earlier identification and intervention, resulting in improved outcomes in pediatric obesity.

  9. Robustness Evaluation of Timber Structures

    DEFF Research Database (Denmark)

    Kirkegaard, Poul Henning; Sørensen, John Dalsgaard

    2009-01-01

    The present paper considers robustness evaluation of a Norwegian sports arena with a structural system of glulam frames. The robustness evaluation is based on the framework for robustness analysis introduced in the Danish Code of Practice for the Safety of Structures and a probabilistic modelling...... of the timber material proposed in the Probabilistic Model Code (PMC) of the Joint Committee on Structural Safety (JCSS). The results show that the requirements for robustness of the structure are highly related to the modelling of the snow load used on the structures when ‘removal of a limited part...

  10. Identification of children with reading difficulties: Cheap can be adequate

    DEFF Research Database (Denmark)

    Poulsen, Mads; Nielsen, Anne-Mette Veber

    Classification of reading difficulties: Cheap screening can be accurate Purpose: Three factors are important for identification of students in need of remedial instruction: accuracy, timeliness, and cost. The identification has to be accurate to be of any use, the identification has to be timely......, inexpensive testing. The present study investigated the classification accuracy of three screening models varying in timeliness and cost. Method: We compared the ROC statistics of three logistic models for predicting end of Grade 2 reading difficulties in a sample of 164 students: 1) an early, comprehensive...... model using a battery of Grade 0 tests, including phoneme awareness, rapid naming, and paired associate learning, 2) a late, comprehensive model adding reading measures from January of Grade 1, and 3) a late, inexpensive model using only group-administered reading measures from January of Grade 1...

  11. Robust and distributed hypothesis testing

    CERN Document Server

    Gül, Gökhan

    2017-01-01

    This book generalizes and extends the available theory in robust and decentralized hypothesis testing. In particular, it presents a robust test for modeling errors which is independent from the assumptions that a sufficiently large number of samples is available, and that the distance is the KL-divergence. Here, the distance can be chosen from a much general model, which includes the KL-divergence as a very special case. This is then extended by various means. A minimax robust test that is robust against both outliers as well as modeling errors is presented. Minimax robustness properties of the given tests are also explicitly proven for fixed sample size and sequential probability ratio tests. The theory of robust detection is extended to robust estimation and the theory of robust distributed detection is extended to classes of distributions, which are not necessarily stochastically bounded. It is shown that the quantization functions for the decision rules can also be chosen as non-monotone. Finally, the boo...

  12. Robustness Evaluation of Timber Structures

    DEFF Research Database (Denmark)

    Kirkegaard, Poul Henning; Sørensen, John Dalsgaard

    2009-01-01

    Robustness of structural systems has obtained a renewed interest due to a much more frequent use of advanced types of structures with limited redundancy and serious consequences in case of failure.......Robustness of structural systems has obtained a renewed interest due to a much more frequent use of advanced types of structures with limited redundancy and serious consequences in case of failure....

  13. Robustness of IPTV business models

    NARCIS (Netherlands)

    Bouwman, H.; Zhengjia, M.; Duin, P. van der; Limonard, S.

    2008-01-01

    The final stage in the STOF method is an evaluation of the robustness of the design, for which the method provides some guidelines. For many innovative services, the future holds numerous uncertainties, which makes evaluating the robustness of a business model a difficult task. In this chapter, we

  14. Robustness Analysis of Kinetic Structures

    DEFF Research Database (Denmark)

    Kirkegaard, Poul Henning; Sørensen, John Dalsgaard

    2009-01-01

    The present paper considers robustness of kinetic structures. Robustness of structures has obtained a renewed interest due to a much more frequent use of advanced types of structures with limited redundancy and serious consequences in case of failure. Especially for these types of structural syst...... systems, it is of interest to investigate how robust the structures are, or what happens if a structural element is added to or removed from the original structure. The present paper discusses this issue for kinetic structures in architecture.......The present paper considers robustness of kinetic structures. Robustness of structures has obtained a renewed interest due to a much more frequent use of advanced types of structures with limited redundancy and serious consequences in case of failure. Especially for these types of structural...

  15. Comparison of robust input shapers

    Science.gov (United States)

    Vaughan, Joshua; Yano, Aika; Singhose, William

    2008-09-01

    The rapid movement of machines is a challenging control problem because it often results in high levels of vibration. As a result, flexible machines are typically moved relatively slowly. Input shaping is a control method that allows much higher speeds of motion by limiting vibration induced by the reference command. To design an input-shaping controller, estimates of the system natural frequency and damping ratio are required. However, real world systems cannot be modeled exactly, making the robustness to modeling errors an important consideration. Many robust input shapers have been developed, but robust shapers typically have longer durations that slow the system response. This creates a compromise between shaper robustness and rise time. This paper analyzes the compromise between rapidity of motion and shaper robustness for several input-shaping methods. Experimental results from a portable bridge crane verify the theoretical predictions.

  16. Theoretical Framework for Robustness Evaluation

    DEFF Research Database (Denmark)

    Sørensen, John Dalsgaard

    2011-01-01

    This paper presents a theoretical framework for evaluation of robustness of structural systems, incl. bridges and buildings. Typically modern structural design codes require that ‘the consequence of damages to structures should not be disproportional to the causes of the damages’. However, although...... the importance of robustness for structural design is widely recognized the code requirements are not specified in detail, which makes the practical use difficult. This paper describes a theoretical and risk based framework to form the basis for quantification of robustness and for pre-normative guidelines...

  17. Robustness of airline route networks

    Science.gov (United States)

    Lordan, Oriol; Sallan, Jose M.; Escorihuela, Nuria; Gonzalez-Prieto, David

    2016-03-01

    Airlines shape their route network by defining their routes through supply and demand considerations, paying little attention to network performance indicators, such as network robustness. However, the collapse of an airline network can produce high financial costs for the airline and all its geographical area of influence. The aim of this study is to analyze the topology and robustness of the network route of airlines following Low Cost Carriers (LCCs) and Full Service Carriers (FSCs) business models. Results show that FSC hubs are more central than LCC bases in their route network. As a result, LCC route networks are more robust than FSC networks.

  18. Robust methods for data reduction

    CERN Document Server

    Farcomeni, Alessio

    2015-01-01

    Robust Methods for Data Reduction gives a non-technical overview of robust data reduction techniques, encouraging the use of these important and useful methods in practical applications. The main areas covered include principal components analysis, sparse principal component analysis, canonical correlation analysis, factor analysis, clustering, double clustering, and discriminant analysis.The first part of the book illustrates how dimension reduction techniques synthesize available information by reducing the dimensionality of the data. The second part focuses on cluster and discriminant analy

  19. 9 CFR 2.40 - Attending veterinarian and adequate veterinary care (dealers and exhibitors).

    Science.gov (United States)

    2010-01-01

    ... 9 Animals and Animal Products 1 2010-01-01 2010-01-01 false Attending veterinarian and adequate... HEALTH INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE ANIMAL WELFARE REGULATIONS Attending Veterinarian and Adequate Veterinary Care § 2.40 Attending veterinarian and adequate veterinary care (dealers and...

  20. Object oriented simulation implementation in support of robust system design

    Energy Technology Data Exchange (ETDEWEB)

    1993-04-01

    A very brief description of two ``classes`` developed for use in design optimization and sensitivity analyses are given. These classes are used in simulations of systems in early design phases as well as system response assessments. The instanciated classes were coupled to system models to demonstrate the practically and efficiency of using these objects in complex robust design processes.

  1. The efficacy of support vector machines (SVM) in robust ...

    Indian Academy of Sciences (India)

    The efficacy of support vector machines (SVM) in robust determination of earthquake early warning magnitudes in central Japan. Ramakrushna Reddy and Rajesh R Nair ..... SVMs were developed to solve the classification problem. However, recently, SVMs have been suc- cessfully extended to regression and density esti-.

  2. Robust Watermarking of Cartographic Images

    Directory of Open Access Journals (Sweden)

    Mauro Barni

    2002-02-01

    Full Text Available We present a method (Text-Based Geometric Normalization—TBGN which, by exploiting the particular content of cartographic images, namely text content, permits to cope with global geometric transformations. First, text is extracted from the to-be-marked map, then text orientation and size are exploited to normalize the image geometry prior to watermark insertion. Watermarking is performed by means of any of the existing algorithms ensuring good robustness against image processing tools. At the decoder side, text is extracted again from the map and used to normalize image geometry. Owing to the robustness of text features with respect to common image manipulations, and to the likely spreading of text all across the digital map, the proposed system exhibits an excellent robustness.

  3. Robust estimation and hypothesis testing

    CERN Document Server

    Tiku, Moti L

    2004-01-01

    In statistical theory and practice, a certain distribution is usually assumed and then optimal solutions sought. Since deviations from an assumed distribution are very common, one cannot feel comfortable with assuming a particular distribution and believing it to be exactly correct. That brings the robustness issue in focus. In this book, we have given statistical procedures which are robust to plausible deviations from an assumed mode. The method of modified maximum likelihood estimation is used in formulating these procedures. The modified maximum likelihood estimators are explicit functions of sample observations and are easy to compute. They are asymptotically fully efficient and are as efficient as the maximum likelihood estimators for small sample sizes. The maximum likelihood estimators have computational problems and are, therefore, elusive. A broad range of topics are covered in this book. Solutions are given which are easy to implement and are efficient. The solutions are also robust to data anomali...

  4. Attractive ellipsoids in robust control

    CERN Document Server

    Poznyak, Alexander; Azhmyakov, Vadim

    2014-01-01

    This monograph introduces a newly developed robust-control design technique for a wide class of continuous-time dynamical systems called the “attractive ellipsoid method.” Along with a coherent introduction to the proposed control design and related topics, the monograph studies nonlinear affine control systems in the presence of uncertainty and presents a constructive and easily implementable control strategy that guarantees certain stability properties. The authors discuss linear-style feedback control synthesis in the context of the above-mentioned systems. The development and physical implementation of high-performance robust-feedback controllers that work in the absence of complete information is addressed, with numerous examples to illustrate how to apply the attractive ellipsoid method to mechanical and electromechanical systems. While theorems are proved systematically, the emphasis is on understanding and applying the theory to real-world situations. Attractive Ellipsoids in Robust Control will a...

  5. Advances in robust fractional control

    CERN Document Server

    Padula, Fabrizio

    2015-01-01

    This monograph presents design methodologies for (robust) fractional control systems. It shows the reader how to take advantage of the superior flexibility of fractional control systems compared with integer-order systems in achieving more challenging control requirements. There is a high degree of current interest in fractional systems and fractional control arising from both academia and industry and readers from both milieux are catered to in the text. Different design approaches having in common a trade-off between robustness and performance of the control system are considered explicitly. The text generalizes methodologies, techniques and theoretical results that have been successfully applied in classical (integer) control to the fractional case. The first part of Advances in Robust Fractional Control is the more industrially-oriented. It focuses on the design of fractional controllers for integer processes. In particular, it considers fractional-order proportional-integral-derivative controllers, becau...

  6. Robustness of digital artist authentication

    DEFF Research Database (Denmark)

    Jacobsen, Robert; Nielsen, Morten

    is in focus, while the robustness has not been considered, i.e. the degree to which the data collection process influences the decision of the method. However, in order for an authentication method to be successful in practice, it needs to be robust to plausible error sources from the data collection....... In this paper we investigate the robustness of the newly proposed authenticity method introduced by the authors based on second generation multiresolution analysis. This is done by modelling a number of realistic factors that can occur in the data collection.......In many cases it is possible to determine the authenticity of a painting from digital reproductions of the paintings; this has been demonstrated for a variety of artists and with different approaches. Common to all these methods in digital artist authentication is that the potential of the method...

  7. A Robust Enough Virtue Epistemology

    DEFF Research Database (Denmark)

    Broncano-Berrocal, Fernando

    2017-01-01

    What is the nature of knowledge? A popular answer to that long-standing question comes from robust virtue epistemology, whose key idea is that knowing is just a matter of succeeding cognitively—i.e., coming to believe a proposition truly—due to an exercise of cognitive ability. Versions of robust...... virtue epistemology further developing and systematizing this idea offer different accounts of the relation that must hold between an agent’s cognitive success and the exercise of her cognitive abilities as well as of the very nature of those abilities. This paper aims to give a new robust virtue...... epistemological account of knowledge based on a different understanding of the nature and structure of the kind of abilities that give rise to knowledge....

  8. [Neonatal ABO incompatibility underlies a potentially severe hemolytic disease of the newborn and requires adequate care].

    Science.gov (United States)

    Senterre, T; Minon, J-M; Rigo, J

    2011-03-01

    ABO allo-immunization is the most frequent hemolytic disease of the newborn and ABO incompatibility is present in 15-25 % of pregnancies. True ABO alloimmunization occurs in approximately one out of 150 births. Intensity is generally lower than in RhD allo-immunization. We report on three cases showing that ABO allo-immunization can lead to severe hemolytic disease of the newborn with potentially threatening hyperbilirubinemia and complications. Early diagnosis and adequate care are necessary to prevent complications in ABO incompatibility. A direct antiglobulin test is the cornerstone of diagnosis and should be performed at birth on cord blood sampling in all group infants born to O mothers, especially if of African origin. Risk factor analysis and attentive clinical monitoring during the first days of life are essential. Vigilance is even more important for infants discharged before the age of 72 h. Every newborn should be assessed for the risk of developing severe hyperbilirubinemia and should be examined by a qualified healthcare professional in the first days of life. Treatment depends on the total serum bilirubin level, which may increase very rapidly in the first 48 h of life in cases of hemolytic disease of the newborn. Phototherapy and, in severe cases, exchange transfusion are used to prevent hyperbilirubinemia encephalopathy. Intravenous immunoglobulins are used to reduce exchange transfusion. Treatments of severe hemolytic disease of the newborn should be provided and performed by trained personnel in neonatal intensive care units. Copyright © 2010 Elsevier Masson SAS. All rights reserved.

  9. Robust Portfolio Optimization Using Pseudodistances

    Science.gov (United States)

    2015-01-01

    The presence of outliers in financial asset returns is a frequently occurring phenomenon which may lead to unreliable mean-variance optimized portfolios. This fact is due to the unbounded influence that outliers can have on the mean returns and covariance estimators that are inputs in the optimization procedure. In this paper we present robust estimators of mean and covariance matrix obtained by minimizing an empirical version of a pseudodistance between the assumed model and the true model underlying the data. We prove and discuss theoretical properties of these estimators, such as affine equivariance, B-robustness, asymptotic normality and asymptotic relative efficiency. These estimators can be easily used in place of the classical estimators, thereby providing robust optimized portfolios. A Monte Carlo simulation study and applications to real data show the advantages of the proposed approach. We study both in-sample and out-of-sample performance of the proposed robust portfolios comparing them with some other portfolios known in literature. PMID:26468948

  10. On Robustness of Power Grids

    NARCIS (Netherlands)

    Koç, Y.

    2015-01-01

    Current and future trends in environmental, economical, and human-caused factors (such as power demand growth, over-ageing of assets in power grids, and extreme weather conditions) challenge power grid robustness in the near future, necessitating research to better analyse and understand the notion

  11. Network Robustness: the whole story

    Science.gov (United States)

    Longjas, A.; Tejedor, A.; Zaliapin, I. V.; Ambroj, S.; Foufoula-Georgiou, E.

    2014-12-01

    A multitude of actual processes operating on hydrological networks may exhibit binary outcomes such as clean streams in a river network that may become contaminated. These binary outcomes can be modeled by node removal processes (attacks) acting in a network. Network robustness against attacks has been widely studied in fields as diverse as the Internet, power grids and human societies. However, the current definition of robustness is only accounting for the connectivity of the nodes unaffected by the attack. Here, we put forward the idea that the connectivity of the affected nodes can play a crucial role in proper evaluation of the overall network robustness and its future recovery from the attack. Specifically, we propose a dual perspective approach wherein at any instant in the network evolution under attack, two distinct networks are defined: (i) the Active Network (AN) composed of the unaffected nodes and (ii) the Idle Network (IN) composed of the affected nodes. The proposed robustness metric considers both the efficiency of destroying the AN and the efficiency of building-up the IN. This approach is motivated by concrete applied problems, since, for example, if we study the dynamics of contamination in river systems, it is necessary to know both the connectivity of the healthy and contaminated parts of the river to assess its ecological functionality. We show that trade-offs between the efficiency of the Active and Idle network dynamics give rise to surprising crossovers and re-ranking of different attack strategies, pointing to significant implications for decision making.

  12. Approximability of Robust Network Design

    NARCIS (Netherlands)

    Olver, N.K.; Shepherd, F.B.

    2014-01-01

    We consider robust (undirected) network design (RND) problems where the set of feasible demands may be given by an arbitrary convex body. This model, introduced by Ben-Ameur and Kerivin [Ben-Ameur W, Kerivin H (2003) New economical virtual private networks. Comm. ACM 46(6):69-73], generalizes the

  13. Mental Models: A Robust Definition

    Science.gov (United States)

    Rook, Laura

    2013-01-01

    Purpose: The concept of a mental model has been described by theorists from diverse disciplines. The purpose of this paper is to offer a robust definition of an individual mental model for use in organisational management. Design/methodology/approach: The approach adopted involves an interdisciplinary literature review of disciplines, including…

  14. Robust Optimization of Database Queries

    Indian Academy of Sciences (India)

    JAYANT

    2011-07-06

    Jul 6, 2011 ... join order [ ((S R) C) or ((R C) S) ? ] join techniques [ Nested-Loops or Sort-Merge or Hash ? ] ○ DBMS query optimizer identifies the optimal. ○ DBMS query optimizer identifies the optimal evaluation strategy: “query execution plan”. July 2011. Robust Query Optimization (IASc Mid-year Meeting). 6 ...

  15. Robust control design with MATLAB

    CERN Document Server

    Gu, Da-Wei; Konstantinov, Mihail M

    2013-01-01

    Robust Control Design with MATLAB® (second edition) helps the student to learn how to use well-developed advanced robust control design methods in practical cases. To this end, several realistic control design examples from teaching-laboratory experiments, such as a two-wheeled, self-balancing robot, to complex systems like a flexible-link manipulator are given detailed presentation. All of these exercises are conducted using MATLAB® Robust Control Toolbox 3, Control System Toolbox and Simulink®. By sharing their experiences in industrial cases with minimum recourse to complicated theories and formulae, the authors convey essential ideas and useful insights into robust industrial control systems design using major H-infinity optimization and related methods allowing readers quickly to move on with their own challenges. The hands-on tutorial style of this text rests on an abundance of examples and features for the second edition: ·        rewritten and simplified presentation of theoretical and meth...

  16. A robust adaptive robot controller

    NARCIS (Netherlands)

    Berghuis, Harry; Berghuis, Harry; Ortega, Romeo; Nijmeijer, Henk

    1993-01-01

    A globally convergent adaptive control scheme for robot motion control with the following features is proposed. First, the adaptation law possesses enhanced robustness with respect to noisy velocity measurements. Second, the controller does not require the inclusion of high gain loops that may

  17. Facial Symmetry in Robust Anthropometrics

    Czech Academy of Sciences Publication Activity Database

    Kalina, Jan

    2012-01-01

    Roč. 57, č. 3 (2012), s. 691-698 ISSN 0022-1198 R&D Projects: GA MŠk(CZ) 1M06014 Institutional research plan: CEZ:AV0Z10300504 Keywords : forensic science * anthropology * robust image analysis * correlation analysis * multivariate data * classification Subject RIV: BB - Applied Statistics, Operational Research Impact factor: 1.244, year: 2012

  18. Robust multiplatform RF emitter localization

    Science.gov (United States)

    Al Issa, Huthaifa; Ordóñez, Raúl

    2012-06-01

    In recent years, position based services has increase. Thus, recent developments in communications and RF technology have enabled system concept formulations and designs for low-cost radar systems using state-of-the-art software radio modules. This research is done to investigate a novel multi-platform RF emitter localization technique denoted as Position-Adaptive RF Direction Finding (PADF). The formulation is based on the investigation of iterative path-loss (i.e., Path Loss Exponent, or PLE) metrics estimates that are measured across multiple platforms in order to autonomously adapt (i.e. self-adjust) of the location of each distributed/cooperative platform. Experiments conducted at the Air-Force Research laboratory (AFRL) indicate that this position-adaptive approach exhibits potential for accurate emitter localization in challenging embedded multipath environments such as in urban environments. The focus of this paper is on the robustness of the distributed approach to RF-based location tracking. In order to localize the transmitter, we use the Received Signal Strength Indicator (RSSI) data to approximate distance from the transmitter to the revolving receivers. We provide an algorithm for on-line estimation of the Path Loss Exponent (PLE) that is used in modeling the distance based on Received Signal Strength (RSS) measurements. The emitter position estimation is calculated based on surrounding sensors RSS values using Least-Square Estimation (LSE). The PADF has been tested on a number of different configurations in the laboratory via the design and implementation of four IRIS wireless sensor nodes as receivers and one hidden sensor as a transmitter during the localization phase. The robustness of detecting the transmitters position is initiated by getting the RSSI data through experiments and then data manipulation in MATLAB will determine the robustness of each node and ultimately that of each configuration. The parameters that are used in the functions are

  19. Inferences and metaphoric comprehension in unilaterally implanted children with adequate formal oral language performance.

    Science.gov (United States)

    Nicastri, Maria; Filipo, Roberto; Ruoppolo, Giovanni; Viccaro, Marika; Dincer, Hilal; Guerzoni, Letizia; Cuda, Domenico; Bosco, Ersilia; Prosperini, Luca; Mancini, Patrizia

    2014-05-01

    of different levels of figurative language complexity (presence or absence of contextual input, degree of transparency and syntactic frozenness). New insight is needed to orient programs in early intervention settings in considering and adequately responding to all these complex communicative need of children with hearing loss. Copyright © 2014 Elsevier Ireland Ltd. All rights reserved.

  20. The Human Right to Adequate Housing: A Tool for Promoting and Protecting Individual and Community Health

    Science.gov (United States)

    Thiele, Bret

    2002-01-01

    The human right to adequate housing is enshrined in international law. The right to adequate housing can be traced to the Universal Declaration of Human Rights, which was unanimously adopted by the world community in 1948. Since that time, the right to adequate housing has been reaffirmed on numerous occasions and further defined and elaborated. A key component of this right is habitability of housing, which should comply with health and safety standards. Therefore, the right to adequate housing provides an additional tool for advocates and others interested in promoting healthful housing and living conditions and thereby protecting individual and community health. PMID:11988432

  1. The human right to adequate housing: a tool for promoting and protecting individual and community health.

    Science.gov (United States)

    Thiele, Bret

    2002-05-01

    The human right to adequate housing is enshrined in international law. The right to adequate housing can be traced to the Universal Declaration of Human Rights, which was unanimously adopted by the world community in 1948. Since that time, the right to adequate housing has been reaffirmed on numerous occasions and further defined and elaborated. A key component of this right is habitability of housing, which should comply with health and safety standards. Therefore, the right to adequate housing provides an additional tool for advocates and others interested in promoting healthful housing and living conditions and thereby protecting individual and community health.

  2. Robust Reliability or reliable robustness? - Integrated consideration of robustness and reliability aspects

    DEFF Research Database (Denmark)

    Kemmler, S.; Eifler, Tobias; Bertsche, B.

    2015-01-01

    products are and vice versa. For a comprehensive understanding and to use existing synergies between both domains, this paper discusses the basic principles of Reliability- and Robust Design theory. The development of a comprehensive model will enable an integrated consideration of both domains...

  3. A Robust Design Applicability Model

    DEFF Research Database (Denmark)

    Ebro, Martin; Lars, Krogstie; Howard, Thomas J.

    2015-01-01

    This paper introduces a model for assessing the applicability of Robust Design (RD) in a project or organisation. The intention of the Robust Design Applicability Model (RDAM) is to provide support for decisions by engineering management considering the relevant level of RD activities...... to be applicable in organisations assigning a high importance to one or more factors that are known to be impacted by RD, while also experiencing a high level of occurrence of this factor. The RDAM supplements existing maturity models and metrics to provide a comprehensive set of data to support management....... The applicability assessment is based on two considerations: 1) Whether there is a correlation between the factors that are important to the project or organisation and the factors that impact from the use of RD and 2) What is the occurrence level of the given factor in the organisation. The RDAM defines RD...

  4. Robust Decentralized Formation Flight Control

    Directory of Open Access Journals (Sweden)

    Zhao Weihua

    2011-01-01

    Full Text Available Motivated by the idea of multiplexed model predictive control (MMPC, this paper introduces a new framework for unmanned aerial vehicles (UAVs formation flight and coordination. Formulated using MMPC approach, the whole centralized formation flight system is considered as a linear periodic system with control inputs of each UAV subsystem as its periodic inputs. Divided into decentralized subsystems, the whole formation flight system is guaranteed stable if proper terminal cost and terminal constraints are added to each decentralized MPC formulation of the UAV subsystem. The decentralized robust MPC formulation for each UAV subsystem with bounded input disturbances and model uncertainties is also presented. Furthermore, an obstacle avoidance control scheme for any shape and size of obstacles, including the nonapriorily known ones, is integrated under the unified MPC framework. The results from simulations demonstrate that the proposed framework can successfully achieve robust collision-free formation flights.

  5. Robust statistics for image deconvolution

    Science.gov (United States)

    Lee, M. A.; Budavári, T.; White, R. L.; Gulian, C.

    2017-10-01

    We present a blind multiframe image-deconvolution method based on robust statistics. The usual shortcomings of iterative optimization of the likelihood function are alleviated by minimizing the M-scale of the residuals, which achieves more uniform convergence across the image. We focus on the deconvolution of astronomical images, which are among the most challenging due to their huge dynamic ranges and the frequent presence of large noise-dominated regions in the images. We show that high-quality image reconstruction is possible even in super-resolution and without the use of traditional regularization terms. Using a robust ρ-function is straightforward to implement in a streaming setting and, hence our method is applicable to the large volumes of astronomy images. The power of our method is demonstrated on observations from the Sloan Digital Sky Survey (Stripe 82) and we briefly discuss the feasibility of a pipeline based on Graphical Processing Units for the next generation of telescope surveys.

  6. Testing Heteroscedasticity in Robust Regression

    Czech Academy of Sciences Publication Activity Database

    Kalina, Jan

    2011-01-01

    Roč. 1, č. 4 (2011), s. 25-28 ISSN 2045-3345 Grant - others:GA ČR(CZ) GA402/09/0557 Institutional research plan: CEZ:AV0Z10300504 Keywords : robust regression * heteroscedasticity * regression quantiles * diagnostics Subject RIV: BB - Applied Statistics , Operational Research http://www.researchjournals.co.uk/documents/Vol4/06%20Kalina.pdf

  7. Robust power system frequency control

    CERN Document Server

    Bevrani, Hassan

    2014-01-01

    This updated edition of the industry standard reference on power system frequency control provides practical, systematic and flexible algorithms for regulating load frequency, offering new solutions to the technical challenges introduced by the escalating role of distributed generation and renewable energy sources in smart electric grids. The author emphasizes the physical constraints and practical engineering issues related to frequency in a deregulated environment, while fostering a conceptual understanding of frequency regulation and robust control techniques. The resulting control strategi

  8. Robust flight control of rotorcraft

    Science.gov (United States)

    Pechner, Adam Daniel

    With recent design improvement in fixed wing aircraft, there has been a considerable interest in the design of robust flight control systems to compensate for the inherent instability necessary to achieve desired performance. Such systems are designed for maximum available retention of stability and performance in the presence of significant vehicle damage or system failure. The rotorcraft industry has shown similar interest in adopting these reconfigurable flight control schemes specifically because of their ability to reject disturbance inputs and provide a significant amount of robustness for all but the most catastrophic of situations. The research summarized herein focuses on the extension of the pseudo-sliding mode control design procedure interpreted in the frequency domain. Application of the technique is employed and simulated on two well known helicopters, a simplified model of a hovering Sikorsky S-61 and the military's Black Hawk UH-60A also produced by Sikorsky. The Sikorsky helicopter model details are readily available and was chosen because it can be limited to pitch and roll motion reducing the number of degrees of freedom and yet contains two degrees of freedom, which is the minimum requirement in proving the validity of the pseudo-sliding control technique. The full order model of a hovering Black Hawk system was included both as a comparison to the S-61 helicopter design system and as a means to demonstrate the scaleability and effectiveness of the control technique on sophisticated systems where design robustness is of critical concern.

  9. Study Concerning Exercising an Adequate Professional Reasoning in Developing the Evaluation and Audit

    Directory of Open Access Journals (Sweden)

    Vârteiu Daniel Petru

    2017-01-01

    Even though there are regulations which clearly specify the way in which an evaluation process, respectively an adequate audit process must take place, for a good management of encountered situations and difficulties, the evaluator, respectively the auditor must exercise an adequate professional reasoning.

  10. The enforceability of the human right to adequate food : a comparative study

    NARCIS (Netherlands)

    mr.dr. Bart F.W. Wernaart

    2013-01-01

    While the right to adequate food is often discussed in the context of developing countries, especially in situations where access to adequate food is a problem on a larger scale, this book focusses on the right to food in two Western countries in which theoretically the circumstances allow this

  11. 9 CFR 2.33 - Attending veterinarian and adequate veterinary care.

    Science.gov (United States)

    2010-01-01

    ... 9 Animals and Animal Products 1 2010-01-01 2010-01-01 false Attending veterinarian and adequate..., DEPARTMENT OF AGRICULTURE ANIMAL WELFARE REGULATIONS Research Facilities § 2.33 Attending veterinarian and adequate veterinary care. (a) Each research facility shall have an attending veterinarian who shall provide...

  12. Defining an adequate sample of earlywood vessels for retrospective injury detection in diffuse-porous species.

    Directory of Open Access Journals (Sweden)

    Estelle Arbellay

    Full Text Available Vessels of broad-leaved trees have been analyzed to study how trees deal with various environmental factors. Cambial injury, in particular, has been reported to induce the formation of narrower conduits. Yet, little or no effort has been devoted to the elaboration of vessel sampling strategies for retrospective injury detection based on vessel lumen size reduction. To fill this methodological gap, four wounded individuals each of grey alder (Alnus incana (L. Moench and downy birch (Betula pubescens Ehrh. were harvested in an avalanche path. Earlywood vessel lumina were measured and compared for each tree between the injury ring built during the growing season following wounding and the control ring laid down the previous year. Measurements were performed along a 10 mm wide radial strip, located directly next to the injury. Specifically, this study aimed at (i investigating the intra-annual duration and local extension of vessel narrowing close to the wound margin and (ii identifying an adequate sample of earlywood vessels (number and intra-ring location of cells attesting to cambial injury. Based on the results of this study, we recommend analyzing at least 30 vessels in each ring. Within the 10 mm wide segment of the injury ring, wound-induced reduction in vessel lumen size did not fade with increasing radial and tangential distances, but we nevertheless advise favoring early earlywood vessels located closest to the injury. These findings, derived from two species widespread across subarctic, mountainous, and temperate regions, will assist retrospective injury detection in Alnus, Betula, and other diffuse-porous species as well as future related research on hydraulic implications after wounding.

  13. Robustness Analysis of Timber Truss Structure

    DEFF Research Database (Denmark)

    Rajčić, Vlatka; Čizmar, Dean; Kirkegaard, Poul Henning

    2010-01-01

    The present paper discusses robustness of structures in general and the robustness requirements given in the codes. Robustness of timber structures is also an issues as this is closely related to Working group 3 (Robustness of systems) of the COST E55 project. Finally, an example of a robustness...... evaluation of a widespan timber truss structure is presented. This structure was built few years ago near Zagreb and has a span of 45m. Reliability analysis of the main members and the system is conducted and based on this a robustness analysis is preformed....

  14. Sustainable Resilient, Robust & Resplendent Enterprises

    DEFF Research Database (Denmark)

    Edgeman, Rick

    to their impact. Resplendent enterprises are introduced with resplendence referring not to some sort of public or private façade, but instead refers to organizations marked by dual brilliance and nobility of strategy, governance and comportment that yields superior and sustainable triple bottom line performance....... Herein resilience, robustness, and resplendence (R3) are integrated with sustainable enterprise excellence (Edgeman and Eskildsen, 2013) or SEE and social-ecological innovation (Eskildsen and Edgeman, 2012) to aid progress of a firm toward producing continuously relevant performance that proceed from...

  15. Robustness Evaluation of Timber Structures

    DEFF Research Database (Denmark)

    Kirkegaard, Poul Henning; Sørensen, John Dalsgaard; Cizmar, D.

    2010-01-01

    The present paper outlines results from working group 3 (WG3) in the EU COST Action E55 – ‘Modelling of the performance of timber structures’. The objectives of the project are related to the three main research activities: the identification and modelling of relevant load and environmental expos...... exposure scenarios, the improvement of knowledge concerning the behaviour of timber structural elements and the development of a generic framework for the assessment of the life-cycle vulnerability and robustness of timber structures....

  16. Robust Software Architecture for Robots

    Science.gov (United States)

    Aghazanian, Hrand; Baumgartner, Eric; Garrett, Michael

    2009-01-01

    Robust Real-Time Reconfigurable Robotics Software Architecture (R4SA) is the name of both a software architecture and software that embodies the architecture. The architecture was conceived in the spirit of current practice in designing modular, hard, realtime aerospace systems. The architecture facilitates the integration of new sensory, motor, and control software modules into the software of a given robotic system. R4SA was developed for initial application aboard exploratory mobile robots on Mars, but is adaptable to terrestrial robotic systems, real-time embedded computing systems in general, and robotic toys.

  17. Trading Robustness Requirements in Mars Entry Trajectory Design

    Science.gov (United States)

    Lafleur, Jarret M.

    2009-01-01

    One of the most important metrics characterizing an atmospheric entry trajectory in preliminary design is the size of its predicted landing ellipse. Often, requirements for this ellipse are set early in design and significantly influence both the expected scientific return from a particular mission and the cost of development. Requirements typically specify a certain probability level (6-level) for the prescribed ellipse, and frequently this latter requirement is taken at 36. However, searches for the justification of 36 as a robustness requirement suggest it is an empirical rule of thumb borrowed from non-aerospace fields. This paper presents an investigation into the sensitivity of trajectory performance to varying robustness (6-level) requirements. The treatment of robustness as a distinct objective is discussed, and an analysis framework is presented involving the manipulation of design variables to effect trades between performance and robustness objectives. The scenario for which this method is illustrated is the ballistic entry of an MSL-class Mars entry vehicle. Here, the design variable is entry flight path angle, and objectives are parachute deploy altitude performance and error ellipse robustness. Resulting plots show the sensitivities between these objectives and trends in the entry flight path angles required to design to these objectives. Relevance to the trajectory designer is discussed, as are potential steps for further development and use of this type of analysis.

  18. Robust Instrumentation[Water treatment for power plant]; Robust Instrumentering

    Energy Technology Data Exchange (ETDEWEB)

    Wik, Anders [Vattenfall Utveckling AB, Stockholm (Sweden)

    2003-08-01

    Cementa Slite Power Station is a heat recovery steam generator (HRSG) with moderate steam data; 3.0 MPa and 420 deg C. The heat is recovered from Cementa, a cement industry, without any usage of auxiliary fuel. The Power station commenced operation in 2001. The layout of the plant is unusual, there are no similar in Sweden and very few world-wide, so the operational experiences are limited. In connection with the commissioning of the power plant a R and D project was identified with the objective to minimise the manpower needed for chemistry management of the plant. The lean chemistry management is based on robust instrumentation and chemical-free water treatment plant. The concept with robust instrumentation consists of the following components; choice of on-line instrumentation with a minimum of O and M and a chemical-free water treatment. The parameters are specific conductivity, cation conductivity, oxygen and pH. In addition to that, two fairly new on-line instruments were included; corrosion monitors and differential pH calculated from specific and cation conductivity. The chemical-free water treatment plant consists of softening, reverse osmosis and electro-deionisation. The operational experience shows that the cycle chemistry is not within the guidelines due to major problems with the operation of the power plant. These problems have made it impossible to reach steady state and thereby not viable to fully verify and validate the concept with robust instrumentation. From readings on the panel of the online analysers some conclusions may be drawn, e.g. the differential pH measurements have fulfilled the expectations. The other on-line analysers have been working satisfactorily apart from contamination with turbine oil, which has been noticed at least twice. The corrosion monitors seem to be working but the lack of trend curves from the mainframe computer system makes it hard to draw any clear conclusions. The chemical-free water treatment has met all

  19. Perspective: Evolution and detection of genetic robustness

    NARCIS (Netherlands)

    Visser, de J.A.G.M.; Hermisson, J.; Wagner, G.P.; Ancel Meyers, L.; Bagheri-Chaichian, H.; Blanchard, J.L.; Chao, L.; Cheverud, J.M.; Elena, S.F.; Fontana, W.; Gibson, G.; Hansen, T.F.; Krakauer, D.; Lewontin, R.C.; Ofria, C.; Rice, S.H.; Dassow, von G.; Wagner, A.; Whitlock, M.C.

    2003-01-01

    Robustness is the invariance of phenotypes in the face of perturbation. The robustness of phenotypes appears at various levels of biological organization, including gene expression, protein folding, metabolic flux, physiological homeostasis, development, and even organismal fitness. The mechanisms

  20. Robust distributed cognitive relay beamforming

    KAUST Repository

    Pandarakkottilil, Ubaidulla

    2012-05-01

    In this paper, we present a distributed relay beamformer design for a cognitive radio network in which a cognitive (or secondary) transmit node communicates with a secondary receive node assisted by a set of cognitive non-regenerative relays. The secondary nodes share the spectrum with a licensed primary user (PU) node, and each node is assumed to be equipped with a single transmit/receive antenna. The interference to the PU resulting from the transmission from the cognitive nodes is kept below a specified limit. The proposed robust cognitive relay beamformer design seeks to minimize the total relay transmit power while ensuring that the transceiver signal-to-interference- plus-noise ratio and PU interference constraints are satisfied. The proposed design takes into account a parameter of the error in the channel state information (CSI) to render the performance of the beamformer robust in the presence of imperfect CSI. Though the original problem is non-convex, we show that the proposed design can be reformulated as a tractable convex optimization problem that can be solved efficiently. Numerical results are provided and illustrate the performance of the proposed designs for different network operating conditions and parameters. © 2012 IEEE.

  1. Methodology in robust and nonparametric statistics

    CERN Document Server

    Jurecková, Jana; Picek, Jan

    2012-01-01

    Introduction and SynopsisIntroductionSynopsisPreliminariesIntroductionInference in Linear ModelsRobustness ConceptsRobust and Minimax Estimation of LocationClippings from Probability and Asymptotic TheoryProblemsRobust Estimation of Location and RegressionIntroductionM-EstimatorsL-EstimatorsR-EstimatorsMinimum Distance and Pitman EstimatorsDifferentiable Statistical FunctionsProblemsAsymptotic Representations for L-Estimators

  2. Gulf War Illnesses: DOD's Conclusions about U.S. Troops' Exposure Cannot Be Adequately Supported

    National Research Council Canada - National Science Library

    Rhodes, Keith

    2004-01-01

    ... (MOD) conclusions about troops' exposure. The GAO found that DoD's and MOD's conclusions about troops' exposure to CW agents, based on DoD and CIA plume modeling, cannot be adequately supported...

  3. Region 8: Colorado Denver 2008 8-hour ozone Adequate Letter (4/2/2018)

    Science.gov (United States)

    EPA letter to Colorado Department of Public Health and Environment determined Metro-Denver/North Front Range ozone attainment plan and 2017 Motor Vehicle Emissions Budgets adequate for transportation conformity and will be announced in Federal Register.

  4. Robust Evaluation for Transportation Network Capacity under Demand Uncertainty

    Directory of Open Access Journals (Sweden)

    Muqing Du

    2017-01-01

    Full Text Available As more and more cities in worldwide are facing the problems of traffic jam, governments have been concerned about how to design transportation networks with adequate capacity to accommodate travel demands. To evaluate the capacity of a transportation system, the prescribed origin and destination (O-D matrix for existing travel demand has been noticed to have a significant effect on the results of network capacity models. However, the exact data of the existing O-D demand are usually hard to be obtained in practice. Considering the fluctuation of the real travel demand in transportation networks, the existing travel demand is represented as uncertain parameters which are defined within a bounded set. Thus, a robust reserve network capacity (RRNC model using min–max optimization is formulated based on the demand uncertainty. An effective heuristic approach utilizing cutting plane method and sensitivity analysis is proposed for the solution of the RRNC problem. Computational experiments and simulations are implemented to demonstrate the validity and performance of the proposed robust model. According to simulation experiments, it is showed that the link flow pattern from the robust solutions to network capacity problems can reveal the probability of high congestion for each link.

  5. Optimization Methods to Minimize Emergence Time While Maintaining Adequate Post-Operative Analgesia

    OpenAIRE

    Tams, Carl; Syroid, Noah; Johnson, Ken B.; Egan, Talmage D.; Westenskow, Dwayne

    2011-01-01

    A rapid emergence from anesthesia combined with an extended duration of adequate analgesia is desired. Difficulties arise when trying to achieve a rapid emergence and provide adequate analgesia for procedures associated with moderate post operative pain. We propose to use pharmacokinetic (PK) and pharmacodynamic (PD) models with optimization techniques to determine anesthetic drugs ratios to improve post-anesthetic outcomes of emergence and analgesia. We hypothesize that optimized propofol, r...

  6. A Bicriteria Approach for Robust Timetabling

    Science.gov (United States)

    Schöbel, Anita; Kratz, Albrecht

    Finding robust solutions of an optimization problem is an important issue in practice. Various concepts on how to define the robustness of an algorithm or of a solution have been suggested. However, there is always a trade-off between the best possible solution and a robust solution, called the price of robustness. In this paper, we analyze this trade-off using the following bicriteria approach. We treat an optimization problem as a bicriteria problem adding the robustness of its solution as an additional objective function. We demonstrate this approach at the aperiodic timetabling problem in which a timetable which is robust under delays is sought. We are able to derive necessary conditions for the resulting Pareto-optimal timetables. For the case in which the robustness is defined as the largest delay for which all connections are maintained we show the bicriteria problem can be solved with the same time complexity as the original single-criteria problem.

  7. Poor neurological sequelae of herpes simplex virus encephalitis in an infant despite adequate antiviral and adjunct corticosteroid therapy

    Directory of Open Access Journals (Sweden)

    Ratna B Basak

    2011-01-01

    Full Text Available A 2-month-old infant presented to our emergency department with fever, altered consciousness, and focal seizures of acute onset. He had vesicular skin lesions over the right preauricular region. CT brain showed a large hypodense lesion involving the left temporo-parietal region, left basal ganglia and left thalamus. MRI brain revealed bilateral multifocal corticomedullary lesions suggestive of encephalitis. CSF-PCR was positive for herpes simplex virus (HSV type I. He was treated with standard dose intravenous acyclovir for 15 days along with a trial of pulse methylprednisolone, but was readmitted within a week with features of an early relapse. The infant survived but developed significant neurological sequelae. Although treatment of HSV is available, the neurological outcome is guarded even with adequate antiviral therapy. Adjunct corticosteroid therapy did not appear to attenuate the neurological sequelae.

  8. Building Robust Systems with Fallible Construction (Elaboration de systemes informatiques robustes a l’architecutre faillible)

    Science.gov (United States)

    2008-04-01

    IST-047 Building Robust Systems with Fallible Construction (Elaboration de systèmes informatiques robustes à l’architecture faillible) Final...IST-047 Building Robust Systems with Fallible Construction (Elaboration de systèmes informatiques robustes à l’architecture faillible...and cost investments. ES - 2 RTO-TR-IST-047 Elaboration de systèmes informatiques robustes à l’architecture faillible (RTO-TR-IST-047

  9. Adaptive robust PID controller design based on a sliding mode for uncertain chaotic systems

    International Nuclear Information System (INIS)

    Chang Weider; Yan Junjuh

    2005-01-01

    A robust adaptive PID controller design motivated from the sliding mode control is proposed for a class of uncertain chaotic systems in this paper. Three PID control gains, K p , K i , and K d , are adjustable parameters and will be updated online with an adequate adaptation mechanism to minimize a previously designed sliding condition. By introducing a supervisory controller, the stability of the closed-loop PID control system under with the plant uncertainty and external disturbance can be guaranteed. Finally, a well-known Duffing-Holmes chaotic system is used as an illustrative to show the effectiveness of the proposed robust adaptive PID controller

  10. Efficient robust conditional random fields.

    Science.gov (United States)

    Song, Dongjin; Liu, Wei; Zhou, Tianyi; Tao, Dacheng; Meyer, David A

    2015-10-01

    Conditional random fields (CRFs) are a flexible yet powerful probabilistic approach and have shown advantages for popular applications in various areas, including text analysis, bioinformatics, and computer vision. Traditional CRF models, however, are incapable of selecting relevant features as well as suppressing noise from noisy original features. Moreover, conventional optimization methods often converge slowly in solving the training procedure of CRFs, and will degrade significantly for tasks with a large number of samples and features. In this paper, we propose robust CRFs (RCRFs) to simultaneously select relevant features. An optimal gradient method (OGM) is further designed to train RCRFs efficiently. Specifically, the proposed RCRFs employ the l1 norm of the model parameters to regularize the objective used by traditional CRFs, therefore enabling discovery of the relevant unary features and pairwise features of CRFs. In each iteration of OGM, the gradient direction is determined jointly by the current gradient together with the historical gradients, and the Lipschitz constant is leveraged to specify the proper step size. We show that an OGM can tackle the RCRF model training very efficiently, achieving the optimal convergence rate [Formula: see text] (where k is the number of iterations). This convergence rate is theoretically superior to the convergence rate O(1/k) of previous first-order optimization methods. Extensive experiments performed on three practical image segmentation tasks demonstrate the efficacy of OGM in training our proposed RCRFs.

  11. Importance of adequate exercise in the detection of coronary heart disease by radionuclide ventriculography

    International Nuclear Information System (INIS)

    Brady, T.J.; Thrall, J.H.; Lo, K.; Pitt, B.

    1980-01-01

    Rest and exercise radionuclide ventriculograms were obtained on 77 symptomatic patients without prior documented coronary artery disease (CAD). Coronary artery disease was present by angiograms in 48. Radionuclide ventriculography (RNV) was abnormal in 41 patients (overall sensitivity 85%). In 29 patients with normal coronary arteries, RNV was normal in 24 (specificity 83%). To determine if the exercise level affects sensitivity, the studies were graded for adequacy of exercise. It was considered adequate if patients developed (a) chest pain, or (b) ST segment depression of at least 1 mm, or (c) if they achieved a pressure rate product greater than 250. Among the 48 patients with coronary artery disease, 35 achieved adequate exercise. Thirty-three had an abnormal RNV (sensitivity 94%). In 13 patients who failed to achieve adequate exercise, RNV was abnormal in eight (sensitivity of only 62%). Some patients with coronary artery disease may have a normal ventricular response at inadequate levels of stress

  12. Robustness Validation in Service-Oriented Architectures

    Science.gov (United States)

    Laranjeiro, Nuno; Vieira, Marco; Madeira, Henrique

    The use of Service Oriented Architecture (SOA) in enterprise applications development is increasing very quickly. In a SOA environment providers supply a set of services that must be robust. Although SOA is being used in business-critical environments, there is no practical means to measure or compare the robustness of services. Robustness failures in such environments are dangerous, as they can be maliciously exploited with severe consequences for the attacked systems. This chapter addresses the problem of robustness validation in SOA environments. The approach proposed is based on a set of robustness tests that is used to discover both programming and design errors. Two concrete examples are presented: one focusing on web services and the other targeting Java Message Service (JMS) middleware. The proposed approach is useful for both providers (to validate the robustness of deployed services) and consumers (to select the services that best fit architectural requirements).

  13. Robustness of Long Span Reciprocal Timber Structures

    DEFF Research Database (Denmark)

    Balfroid, Nathalie; Kirkegaard, Poul Henning; Sassone, Mario SASSONE

    2011-01-01

    engineer may take necessary steps to design robust structures that are insensitive to accidental circumstances. The present paper makes a discussion of such robustness issues related to the future development of reciprocal timber structures. The paper concludes that these kind of structures can have...... a potential as long span timber structures in real projects if they are carefully designed with respect to the overall robustness strategies....

  14. Molecular mechanisms of robustness in plants.

    Science.gov (United States)

    Lempe, Janne; Lachowiec, Jennifer; Sullivan, Alessandra M; Queitsch, Christine

    2013-02-01

    Robustness, the ability of organisms to buffer phenotypes against perturbations, has drawn renewed interest among developmental biologists and geneticists. A growing body of research supports an important role of robustness in the genotype to phenotype translation, with far-reaching implications for evolutionary processes and disease susceptibility. Similar to animals and fungi, plant robustness is a function of genetic network architecture. Most perturbations are buffered; however, perturbation of network hubs destabilizes many traits. Here, we review recent advances in identifying molecular robustness mechanisms in plants that have been enabled by a combination of classical genetics and population genetics with genome-scale data. Copyright © 2012 Elsevier Ltd. All rights reserved.

  15. A Survey on Robustness in Railway Planning

    DEFF Research Database (Denmark)

    Lusby, Richard Martin; Larsen, Jesper; Bull, Simon Henry

    2018-01-01

    in the quality of solutions to individual planning problems, and of operations in general. Robustness in general is the capacity for some system to absorb or resist changes. In the context of railway robustness it is often taken to be the capacity for operations to continue at some level when faced...... with a disruption such as delay or failure. This has resulted in more attention given to the inclusion of robustness measures and objectives in individual planning problems, and to the providing of tools to ensure operations continue under disrupted situations. In this paper we survey the literature on robustness...

  16. Robustness: confronting lessons from physics and biology.

    Science.gov (United States)

    Lesne, Annick

    2008-11-01

    The term robustness is encountered in very different scientific fields, from engineering and control theory to dynamical systems to biology. The main question addressed herein is whether the notion of robustness and its correlates (stability, resilience, self-organisation) developed in physics are relevant to biology, or whether specific extensions and novel frameworks are required to account for the robustness properties of living systems. To clarify this issue, the different meanings covered by this unique term are discussed; it is argued that they crucially depend on the kind of perturbations that a robust system should by definition withstand. Possible mechanisms underlying robust behaviours are examined, either encountered in all natural systems (symmetries, conservation laws, dynamic stability) or specific to biological systems (feedbacks and regulatory networks). Special attention is devoted to the (sometimes counterintuitive) interrelations between robustness and noise. A distinction between dynamic selection and natural selection in the establishment of a robust behaviour is underlined. It is finally argued that nested notions of robustness, relevant to different time scales and different levels of organisation, allow one to reconcile the seemingly contradictory requirements for robustness and adaptability in living systems.

  17. Presymptomatic diagnosis with MRI and adequate treatment ameliorate the outcome after natalizumab-associated progressive multifocal leukoencephalopathy (PML.

    Directory of Open Access Journals (Sweden)

    Hans eLindå

    2013-02-01

    Full Text Available Natalizumab (Tysabri® is a monoclonal antibody that prevents inflammatory cells from binding to brain endothelial cells and passing into the brain parenchyma. Natalizumab is a highly effective treatment for relapsing-remitting multiple sclerosis (MS. Progressive multifocal leukoencephalopathy (PML is an opportunistic brain JC virus infection that has been shown to be associated with natalizumab treatment. We describe PML in a patient with MS after 44 monthly infusions of natalizumab. With the aid of a routine MRI scan, PML was detected before any unambiguous clinical manifestations had emerged. PML was treated with plasma exchange to accelerate removal of natalizumab. Mirtazapine and mefloquine was promptly added and approximately one month after plasma exchange, when an immune-reconstitution-inflammatory-syndrome (IRIS appeared, steroid treatment was initiated. Steroid treatment was then continued until no virus could be detected in the cerebrospinal fluid. The outcome was favourable. We believe that this case clearly illustrates the importance of an early, presymptomatic, detection of PML and an adequate treatment. We also propose that surveillance with MRI scans, every 3 months after 24 months of treatment, should be performed in JC virus antibody positive natalizumab-treated MS patients in order to detect PML in an early phase.

  18. Robustness indicators and capacity models for railway networks

    DEFF Research Database (Denmark)

    Jensen, Lars Wittrup

    In a world continuous striving for higher mobility and the use of more sustainable modes of transport, there is a constant pressure on utilising railway capacity better and, at the same time, obtaining a high robustness against delays. During the planning of railway operations and infrastructure...... this can be assisted by improving decision support systems to enable planners to use their time more efficiently. In the context of strategic (long-term) planning, efficient decision-support tools translate into being able to evaluate infrastructure and timetable scenarios fast with little data input....... This has motivated the research conducted and described in this thesis, where the objective has been to develop and improve existing methods to achieve timetable and infrastructure plans with robust capacity utilisation aimed at the strategic and early tactical planning phases....

  19. Trends and determinants of adequate gastroprotection in patients chronically using NSAIDs.

    Science.gov (United States)

    Helsper, Charles W; Smeets, Hugo M; Numans, Mattijs E; Knol, Mirjam J; Hoes, Arno W; de Wit, Niek J

    2009-09-01

    To identify determinants and trends of gastroprotection in patients chronically using NSAIDs. retrospective cohort study. Agis Health Database (AHD) containing annual prescription records of approximately 1.5 million patients. All patients using more than 180 daily defined doses (DDD) annually, of any NSAID from 2001 to 2007. prevalence of NSAID use, adequate prescription of gastroprotective drugs (PPI, misoprostol or COX-2 inhibitor use), determinants of adequate gastroprotection. The percentage of patients chronically using NSAIDs rose from 7.3% of the total NSAIDs users in 2001 to 7.5% in 2007. The percentage of patients on NSAIDs receiving adequate gastroprotective medication in line with actual guidelines increased from 39.6% in 2001 to 69.9% in 2007. Age over 70, co-prescription of SSRI, coumarine and steroids and arthritis are the main clinical factors predicting adequate prescription. The prevalence of NSAID prescription and the risk of gastric complications is increasing steadily. Although the number of patients receiving gastroprotective medication is also increasing, over 30% of the patients at risk for GI complications were left unprotected in 2007. In order to improve protection rates in patients using NSAIDs and to decrease NSAID related hospital admissions in the future, the implementation of gastroprotection guidelines needs to be improved.

  20. Long-Term Recurrent Subarachnoid Hemorrhage After Adequate Coiling Versus Clipping of Ruptured Intracranial Aneurysms

    NARCIS (Netherlands)

    Schaafsma, Joanna D.; Sprengers, Marieke E.; van Rooij, Willem Jan; Sluzewski, Menno; Majoie, Charles B. L. M.; Wermer, Marieke J. H.; Rinkel, Gabriel J. E.

    Background and Purpose-Coiling is increasingly used as treatment for intracranial aneurysms. Despite its favorable short-term outcome, concerns exist about long-term reopening and inherent risk of recurrent subarachnoid hemorrhage (SAH). We hypothesized a higher risk for recurrent SAH after adequate

  1. The Unequal Effect of Adequate Yearly Progress: Evidence from School Visits

    Science.gov (United States)

    Brown, Abigail B.; Clift, Jack W.

    2010-01-01

    The authors report insights, based on annual site visits to elementary and middle schools in three states from 2004 to 2006, into the incentive effect of the No Child Left Behind Act's requirement that increasing percentages of students make Adequate Yearly Progress (AYP) in every public school. They develop a framework, drawing on the physics…

  2. 33 CFR 155.4050 - Ensuring that the salvors and marine firefighters are adequate.

    Science.gov (United States)

    2010-07-01

    ... firefighters are adequate. (a) You are responsible for determining the adequacy of the resource providers you intend to include in your plan. (b) When determining adequacy of the resource provider, you must select a resource provider that meets the following selection criteria to the maximum extent possible: (1) Resource...

  3. Towards 31Mg-β-NMR resonance linewidths adequate for applications in magnesium chemistry

    DEFF Research Database (Denmark)

    Stachura, M.; McFadden, R. M. L.; Chatzichristos, A.

    2017-01-01

    The span of most chemical shifts recorded in conventional 25Mg-NMR spectroscopy is ~ 100 ppm. Accordingly, linewidths of ~ 10 ppm or better are desirable to achieve adequate resolution for applications in chemistry. Here we present first high-field 31Mg- β-NMR measurements of 31Mg+ ions implanted...

  4. 12 CFR 702.303 - Prompt corrective action for “adequately capitalized” new credit unions.

    Science.gov (United States)

    2010-01-01

    ... capitalizedâ new credit unions. 702.303 Section 702.303 Banks and Banking NATIONAL CREDIT UNION ADMINISTRATION REGULATIONS AFFECTING CREDIT UNIONS PROMPT CORRECTIVE ACTION Alternative Prompt Corrective Action for New Credit Unions § 702.303 Prompt corrective action for “adequately capitalized” new credit unions...

  5. Human milk feeding supports adequate growth in infants

    Science.gov (United States)

    Despite current nutritional strategies, premature infants remain at high risk for extrauterine growth restriction. The use of an exclusive human milk-based diet is associated with decreased incidence of necrotizing enterocolitis (NEC), but concerns exist about infants achieving adequate growth. The ...

  6. 42 CFR 413.24 - Adequate cost data and cost finding.

    Science.gov (United States)

    2010-10-01

    ... Reports § 413.24 Adequate cost data and cost finding. (a) Principle. Providers receiving payment on the... will be acceptable, subject to appropriate treatment of capital expenditures. (b) Definitions—(1) Cost... provider to ascertain costs of the various types of services furnished. It is the determination of these...

  7. 40 CFR 152.20 - Exemptions for pesticides adequately regulated by another Federal agency.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 23 2010-07-01 2010-07-01 false Exemptions for pesticides adequately regulated by another Federal agency. 152.20 Section 152.20 Protection of Environment ENVIRONMENTAL... microscopic element, including, but not limited to, viruses. (4) All living plants intended for use as...

  8. Adequate Education: Issues in Its Definition and Implementation. School Finance Project, Working Papers.

    Science.gov (United States)

    Tron, Esther, Ed.

    Section 1203 of the Education Amendments of 1978 mandated the undertaking of studies concerning the adequate financing of elementary and secondary education in the 1980s. Created to carry out this mandate, the School Finance Project established as one of its goals reporting to Congress on issues implicit in funding educational adequacy. Several…

  9. Protecting the Home and Adequate Housing - Living in a Caravan or Trailer as a Human Right

    NARCIS (Netherlands)

    Donders, Y.

    2016-01-01

    Many Roma, gypsies and travellers live in caravans or trailers, sometimes in together trailer parks or camps. This article analyses how this specific lifestyle connected to their housing is protected under the various regimes and provisions of international human rights law. Home and adequate

  10. Does the new conceptual framework provide adequate concepts for reporting relevant information about performance?

    NARCIS (Netherlands)

    Brouwer, A.; Faramarzi, A; Hoogendoorn, M.

    2014-01-01

    The basic question we raise in this paper is whether the 2013 Discussion Paper (DP 2013) on the Conceptual Framework provides adequate principles for reporting an entity’s performance and what improvements could be made in light of both user needs and evidence from academic literature. DP 2013

  11. Soil Phosphorus Level Adequate for Growth of Ocala Sand Pine Seedlings, A Greenhouse Evaluation

    Science.gov (United States)

    James B. Baker; R. H. Brendemuehl

    1972-01-01

    A greenhouse study was conducted to determine the level of soil P adequate for satisfactory growth of Ocala sand pine (Pinus clausa (Chapm.) Vasey) seedlings. Various quantities of Lakeland sand with low and high P contents were blended to provide soil mixtures with a range of available P. Ocala sand pine seedlings were grown in these mixtures for 10...

  12. Maintaining adequate nutrient supply - Principles, decision-support tools, and best management practices [Chapter 6

    Science.gov (United States)

    Robert B. Harrison; Douglas A. Maguire; Deborah Page-Dumroese

    2011-01-01

    Maintaining adequate nutrient supply to maintain or enhance tree vigor and forest growth requires conservation of topsoil and soil organic matter. Sometimes nutrient amendments are also required to supplement inherent nutrient-pool limitations or replenish nutrients removed in harvested material. The goal is to maintain the productive potential of the soil and, when...

  13. Duty beares and their right to adequate food obligations: roles and ...

    African Journals Online (AJOL)

    Peter Milton Rukundo

    2011-12-07

    Dec 7, 2011 ... Department of Health, Nutrition and Management, Faculty of Health Sciences, Oslo and Akershus ... capacity of duty bearers in the realization of the right to adequate food in Uganda. Structured interviews were ... Secretariat in the year 2000 to fast-track agricultural transformation and food security through ...

  14. Alabama's Foundation Program: An Adequate and Equitable School Funding Mechanism?

    Science.gov (United States)

    Coe, Dennis Randal

    2016-01-01

    The purpose of this study was to determine the extent to which the foundation program was an adequate and equitable funding mechanism for public schools in the state of Alabama. This study analyzed funding and academic data and evaluated adequacy and equity through the lenses of poverty, geographic location, local tax effort, and type of school…

  15. Calculation of the Cost of an Adequate Education in Kentucky: A Professional Judgment Approach

    Directory of Open Access Journals (Sweden)

    Deborah A. Verstegen

    2004-02-01

    Full Text Available What is an adequate education and how much does it cost? In 1989, Kentucky’s State Supreme Court found the entire system of education unconstitutional-“all of its parts and parcels”. The Court called for all children to have access to an adequate education, one that is uniform and has as its goal the development of seven capacities, including: (i “sufficient oral and written communication skills to enable students to function in a complex and rapidly changing civilization . . . .and (vii sufficient levels of academic or vocational skills to enable public school students to compete favorably with their counterparts in surrounding states, in academics or in the job market”. Now, over a decade later, key questions remain regarding whether these objectives have been fulfilled. This research is designed to calculate the cost of an adequate education by aligning resources to State standards, laws and objectives, using a professional judgment approach. Seven focus groups were convened for this purpose and the scholarly literature was reviewed to provide multiple inputs into study findings. The study produced a per pupil base cost for each of three prototype school districts and an total statewide cost, with the funding gap between existing revenue and the revenue needed for current operations of $1.097 billion per year (2001-02. Additional key resource requirements needed to achieve an adequate education, identified by professional judgment panels, include: (1 extending the school year for students and teachers, (2 adding voluntary half-day preschool for three and four year olds, and (3 raising teacher salaries. This increases the funding gap to $1.23 billion and suggests that significant new funding is required over time if the Commonwealth of Kentucky is to provide an adequate and equitable education of high quality for all children and youth as directed by the State Supreme Court.

  16. In Silico Design of Robust Bolalipid Membranes

    NARCIS (Netherlands)

    Bulacu, Monica; Periole, Xavier; Marrink, Siewert J.; Périole, Xavier

    The robustness of microorganisms used in industrial fermentations is essential for the efficiency and yield of the production process. A viable tool to increase the robustness is through engineering of the cell membrane and especially by incorporating lipids from species that survive under harsh

  17. Robust bayesian inference of generalized Pareto distribution ...

    African Journals Online (AJOL)

    Abstract. In this work, robust Bayesian estimation of the generalized Pareto distribution is proposed. The methodology is presented in terms of oscillation of posterior risks of the Bayesian estimators. By using a Monte Carlo simulation study, we show that, under a suitable generalized loss function, we can obtain a robust ...

  18. Globalized robust optimization for nonlinear uncertain inequalities

    NARCIS (Netherlands)

    Ben-Tal, A.; Brekelmans, Ruud; den Hertog, Dick; Vial, J.P.

    Robust optimization is a methodology that can be applied to problems that are affected by uncertainty in their parameters. The classical robust counterpart of a problem requires the solution to be feasible for all uncertain parameter values in a so-called uncertainty set and offers no guarantees for

  19. Implicitly Weighted Methods in Robust Image Analysis

    Czech Academy of Sciences Publication Activity Database

    Kalina, Jan

    2012-01-01

    Roč. 44, č. 3 (2012), s. 449-462 ISSN 0924-9907 R&D Projects: GA MŠk(CZ) 1M06014 Institutional research plan: CEZ:AV0Z10300504 Keywords : robustness * high breakdown point * outlier detection * robust correlation analysis * template matching * face recognition Subject RIV: BB - Applied Statistics, Operational Research Impact factor: 1.767, year: 2012

  20. Extending the Scope of Robust Quadratic Optimization

    NARCIS (Netherlands)

    Marandi, Ahmadreza; Ben-Tal, A.; den Hertog, Dick; Melenberg, Bertrand

    In this paper, we derive tractable reformulations of the robust counterparts of convex quadratic and conic quadratic constraints with concave uncertainties for a broad range of uncertainty sets. For quadratic constraints with convex uncertainty, it is well-known that the robust counterpart is, in

  1. A practical guide to robust optimization

    NARCIS (Netherlands)

    Gorissen, Bram; Yanikoglu, Ihsan; den Hertog, Dick

    Robust optimization is a young and active research field that has been mainly developed in the last 15 years. Robust optimization is very useful for practice, since it is tailored to the information at hand, and it leads to computationally tractable formulations. It is therefore remarkable that

  2. Robust dissipativity for uncertain impulsive dynamical systems

    Directory of Open Access Journals (Sweden)

    Liu Bin

    2003-01-01

    Full Text Available We discuss the robust dissipativity with respect to the quadratic supply rate for uncertain impulsive dynamical systems. By employing the Hamilton-Jacobi inequality approach, some sufficient conditions of robust dissipativity for this kind of system are established. Finally, we specialize the obtained results to the case of uncertain linear impulsive dynamical systems.

  3. What is it to be sturdy (robust)?

    DEFF Research Database (Denmark)

    Nielsen, Niss Skov; Zwisler, Lars Pagter; Bojsen, Ann Kristina Mikkelsen

    Purpose: This paper intends to give a first insight into the concept of being "sturdy/robust"; To develop and test a Danish model of how to measure sturdi-ness/robustness; To test the scale's ability to identify people in emergency situa-tions who have high risk of developing psychological illness....

  4. Applying Robust Design in an Industrial Context

    DEFF Research Database (Denmark)

    Christensen, Martin Ebro

    mechanical architectures. Furthermore a set of 15 robust design principles for reducing the variation in functional performance is compiled in a format directly supporting the work of the design engineer. With these foundational methods in place, the existing tools, methods and KPIs of Robust Design...

  5. Recoverable Robustness in Shunting and Timetabling

    Science.gov (United States)

    Cicerone, Serafino; D'Angelo, Gianlorenzo; di Stefano, Gabriele; Frigioni, Daniele; Navarra, Alfredo; Schachtebeck, Michael; Schöbel, Anita

    In practical optimization problems, disturbances to a given instance are unavoidable due to unpredictable events which can occur when the system is running. In order to face these situations, many approaches have been proposed during the last years in the area of robust optimization. The basic idea of robustness is to provide a solution which is able to keep feasibility even if the input instance is disturbed, at the cost of optimality. However, the notion of robustness in every day life is much broader than that pursued in the area of robust optimization so far. In fact, robustness is not always suitable unless some recovery strategies are introduced. Recovery strategies are some capabilities that can be used when disturbing events occur, in order to keep the feasibility of the pre-computed solution. This suggests to study robustness and recoverability in a unified framework. Recently, a first tentative of unifying the notions of robustness and recoverability into a new integrated notion of recoverable robustness has been done in the context of railway optimization.

  6. Boolean networks with robust and reliable trajectories

    International Nuclear Information System (INIS)

    Schmal, Christoph; Peixoto, Tiago P; Drossel, Barbara

    2010-01-01

    We construct and investigate Boolean networks that follow a given reliable trajectory in state space, which is insensitive to fluctuations in the updating schedule and which is also robust against noise. Robustness is quantified as the probability that the dynamics return to the reliable trajectory after a perturbation of the state of a single node. In order to achieve high robustness, we navigate through the space of possible update functions by using an evolutionary algorithm. We constrain the networks to those having the minimum number of connections required to obtain the reliable trajectory. Surprisingly, we find that robustness always reaches values close to 100% during the evolutionary optimization process. The set of update functions can be evolved such that it differs only slightly from that of networks that were not optimized with respect to robustness. The state space of the optimized networks is dominated by the basin of attraction of the reliable trajectory.

  7. International Conference on Robust Statistics 2015

    CERN Document Server

    Basu, Ayanendranath; Filzmoser, Peter; Mukherjee, Diganta

    2016-01-01

    This book offers a collection of recent contributions and emerging ideas in the areas of robust statistics presented at the International Conference on Robust Statistics 2015 (ICORS 2015) held in Kolkata during 12–16 January, 2015. The book explores the applicability of robust methods in other non-traditional areas which includes the use of new techniques such as skew and mixture of skew distributions, scaled Bregman divergences, and multilevel functional data methods; application areas being circular data models and prediction of mortality and life expectancy. The contributions are of both theoretical as well as applied in nature. Robust statistics is a relatively young branch of statistical sciences that is rapidly emerging as the bedrock of statistical analysis in the 21st century due to its flexible nature and wide scope. Robust statistics supports the application of parametric and other inference techniques over a broader domain than the strictly interpreted model scenarios employed in classical statis...

  8. How Robust is Your System Resilience?

    Science.gov (United States)

    Homayounfar, M.; Muneepeerakul, R.

    2017-12-01

    Robustness and resilience are concepts in system thinking that have grown in importance and popularity. For many complex social-ecological systems, however, robustness and resilience are difficult to quantify and the connections and trade-offs between them difficult to study. Most studies have either focused on qualitative approaches to discuss their connections or considered only one of them under particular classes of disturbances. In this study, we present an analytical framework to address the linkage between robustness and resilience more systematically. Our analysis is based on a stylized dynamical model that operationalizes a widely used concept framework for social-ecological systems. The model enables us to rigorously define robustness and resilience and consequently investigate their connections. The results reveal the tradeoffs among performance, robustness, and resilience. They also show how the nature of the such tradeoffs varies with the choices of certain policies (e.g., taxation and investment in public infrastructure), internal stresses and external disturbances.

  9. Robustness or resilience? Managing the intersection of ecology and engineering in an urban Alaskan fishery

    Directory of Open Access Journals (Sweden)

    Meagan B. Krupa

    2014-06-01

    Full Text Available Systems theories of robustness and resilience, which are derived from engineering and ecology, respectively, have been increasingly applied to social-ecological systems (SESs. Social-ecological robustness has been applied primarily to management of physical dimensions of SESs (e.g., water management and resilience to management of ecological dimensions of SESs (e.g., rangelands. However, cases of highly engineered systems have yet to be adequately evaluated by either approach. We find the robustness framework serves to better explain management options of a highly engineered, ecologically-based SES, the lower Ship Creek fishery in Anchorage, Alaska, USA. Robustness applies well to this system because its dynamics are highly engineered through both structures and institutions. Even the salmon are products of a hatchery fishery that operates independently of many ecological variables and feedbacks within the system. However, robustness theory has yet to develop a prescriptive method for management that can assist practitioners. We conclude by applying Ostrom's design principles to the system dynamics to assess opportunities for increasing the robustness of this urban fishery.

  10. Deriving robust and globalized robust solutions of uncertain linear programs having general convex uncertainty sets

    NARCIS (Netherlands)

    Gorissen, B.L.; Blanc, J.P.C.; den Hertog, D.; Ben-Tal, A.

    We propose a new way to derive tractable robust counterparts of a linear program based on the duality between the robust (“pessimistic”) primal problem and its “optimistic” dual. First we obtain a new convex reformulation of the dual problem of a robust linear program, and then show how to construct

  11. Are new registered nursing graduates adequately prepared to be competent practitioners? a Victorian study

    OpenAIRE

    Missen, Karen Lee

    2017-01-01

    Abstract Background: Each year, thousands of new nursing graduates join the health workforce in Australia. Evidence from the literature suggests that undergraduate nursing programs do not adequately prepare these graduates to be practice-ready and competent on graduation. Technological advances in healthcare, increased acuity of care, and increased numbers of hospital admissions due to an ageing population and higher prevalence of chronic disease means that the issue of nurse graduates...

  12. Evaluation of lymph node numbers for adequate staging of Stage II and III colon cancer

    Directory of Open Access Journals (Sweden)

    Bumpers Harvey L

    2011-05-01

    Full Text Available Abstract Background Although evaluation of at least 12 lymph nodes (LNs is recommended as the minimum number of nodes required for accurate staging of colon cancer patients, there is disagreement on what constitutes an adequate identification of such LNs. Methods To evaluate the minimum number of LNs for adequate staging of Stage II and III colon cancer, 490 patients were categorized into groups based on 1-6, 7-11, 12-19, and ≥ 20 LNs collected. Results For patients with Stage II or III disease, examination of 12 LNs was not significantly associated with recurrence or mortality. For Stage II (HR = 0.33; 95% CI, 0.12-0.91, but not for Stage III patients (HR = 1.59; 95% CI, 0.54-4.64, examination of ≥20 LNs was associated with a reduced risk of recurrence within 2 years. However, examination of ≥20 LNs had a 55% (Stage II, HR = 0.45; 95% CI, 0.23-0.87 and a 31% (Stage III, HR = 0.69; 95% CI, 0.38-1.26 decreased risk of mortality, respectively. For each six additional LNs examined from Stage III patients, there was a 19% increased probability of finding a positive LN (parameter estimate = 0.18510, p Conclusions Thus, the 12 LN cut-off point cannot be supported as requisite in determining adequate staging of colon cancer based on current data. However, a minimum of 6 LNs should be examined for adequate staging of Stage II and III colon cancer patients.

  13. Which Food Security Determinants Predict Adequate Vegetable Consumption among Rural Western Australian Children?

    Directory of Open Access Journals (Sweden)

    Stephanie L. Godrich

    2017-01-01

    Full Text Available Improving the suboptimal vegetable consumption among the majority of Australian children is imperative in reducing chronic disease risk. The objective of this research was to determine whether there was a relationship between food security determinants (FSD (i.e., food availability, access, and utilisation dimensions and adequate vegetable consumption among children living in regional and remote Western Australia (WA. Caregiver-child dyads (n = 256 living in non-metropolitan/rural WA completed cross-sectional surveys that included questions on FSD, demographics and usual vegetable intake. A total of 187 dyads were included in analyses, which included descriptive and logistic regression analyses via IBM SPSS (version 23. A total of 13.4% of children in this sample had adequate vegetable intake. FSD that met inclusion criteria (p ≤ 0.20 for multivariable regression analyses included price; promotion; quality; location of food outlets; variety of vegetable types; financial resources; and transport to outlets. After adjustment for potential demographic confounders, the FSD that predicted adequate vegetable consumption were, variety of vegetable types consumed (p = 0.007, promotion (p = 0.017, location of food outlets (p = 0.027, and price (p = 0.043. Food retail outlets should ensure that adequate varieties of vegetable types (i.e., fresh, frozen, tinned are available, vegetable messages should be promoted through food retail outlets and in community settings, towns should include a range of vegetable purchasing options, increase their reliance on a local food supply and increase transport options to enable affordable vegetable purchasing.

  14. Transthoracic echocardiography is adequate for intraprocedural guidance of transcatheter aortic valve implantation.

    Science.gov (United States)

    Jain, Renuka; O'Hair, Daniel P; Bajwa, Tanvir K; Ignatowski, Denise; Harland, Daniel; Kirby, Amanda M; Hammonds, Tracy; Allaqaband, Suhail Q; Kay, Jonathan; Khandheria, Bijoy K

    2017-12-01

    While transcatheter aortic valve implantation (TAVI) has traditionally been supported intraprocedurally by transoesophageal echocardiography (TOE), transthoracic echocardiography (TTE) is increasingly being used. We evaluated echocardiographic imaging characteristics and clinical outcomes in patients who underwent TTE during TAVI (TTE-TAVI). A select team of dedicated sonographers and interventional echocardiographers performed TTE-TAVI in 278 patients, all of whom underwent TAVI through transfemoral access. We implanted the Medtronic EVOLUT R valve in 258 patients (92.8%). TTE images were acquired immediately pre-procedure by a dedicated sonographer in the cardiac catheterization laboratory with the patient in the supine position. TTE was then performed post deployment of TAVI. In the procedure, TTE image quality was fair or better in 249 (89.6%) cases. Color-flow Doppler was adequate or better in 275 (98.9%) cases. In 2 cases, paravalvular regurgitation (PVL) could not be assessed confidently by echocardiography due to poor image quality; in those cases, PVL was assessed by fluoroscopy, aortic root injection and invasive hemodynamics. Both TTE and invasive hemodynamics were used in the assessment of need for post-deployment stent ballooning ( n  = 23, 8.3%). TTE adequately recognized new pericardial effusion in 3 cases. No case required TOE conversion for image quality. There was only 1 case of intraprocedural TTE failing to recognize moderate PVL, without clinical implication. In 99% of patients, TTE-TAVI adequately assessed PVL compared with 24-h and 1-month follow-up TTE. With the current generation of TAVI, TTE-TAVI is adequate intraprocedurally when performed by specialized sonographers and dedicated cardiologists in a highly experienced TAVI center. © 2017 The authors.

  15. Self-esteem, social support, and satisfaction differences in women with adequate and inadequate prenatal care.

    Science.gov (United States)

    Higgins, P; Murray, M L; Williams, E M

    1994-03-01

    This descriptive, retrospective study examined levels of self-esteem, social support, and satisfaction with prenatal care in 193 low-risk postpartal women who obtained adequate and inadequate care. The participants were drawn from a regional medical center and university teaching hospital in New Mexico. A demographic questionnaire, the Coopersmith self-esteem inventory, the personal resource questionnaire part 2, and the prenatal care satisfaction inventory were used for data collection. Significant differences were found in the level of education, income, insurance, and ethnicity between women who received adequate prenatal care and those who received inadequate care. Women who were likely to seek either adequate or inadequate prenatal care were those whose total family income was $10,000 to $19,999 per year and high school graduates. Statistically significant differences were found in self-esteem, social support, and satisfaction between the two groups of women. Strategies to enhance self-esteem and social support have to be developed to reach women at risk for receiving inadequate prenatal care.

  16. Global Risk Assessment of Aflatoxins in Maize and Peanuts: Are Regulatory Standards Adequately Protective?

    Science.gov (United States)

    Wu, Felicia

    2013-01-01

    The aflatoxins are a group of fungal metabolites that contaminate a variety of staple crops, including maize and peanuts, and cause an array of acute and chronic human health effects. Aflatoxin B1 in particular is a potent liver carcinogen, and hepatocellular carcinoma (HCC) risk is multiplicatively higher for individuals exposed to both aflatoxin and chronic infection with hepatitis B virus (HBV). In this work, we sought to answer the question: do current aflatoxin regulatory standards around the world adequately protect human health? Depending upon the level of protection desired, the answer to this question varies. Currently, most nations have a maximum tolerable level of total aflatoxins in maize and peanuts ranging from 4 to 20ng/g. If the level of protection desired is that aflatoxin exposures would not increase lifetime HCC risk by more than 1 in 100,000 cases in the population, then most current regulatory standards are not adequately protective even if enforced, especially in low-income countries where large amounts of maize and peanuts are consumed and HBV prevalence is high. At the protection level of 1 in 10,000 lifetime HCC cases in the population, however, almost all aflatoxin regulations worldwide are adequately protective, with the exception of several nations in Africa and Latin America. PMID:23761295

  17. A one-item question with a Likert or Visual Analog Scale adequately measured current anxiety.

    Science.gov (United States)

    Davey, Heather M; Barratt, Alexandra L; Butow, Phyllis N; Deeks, Jonathan J

    2007-04-01

    To determine whether a single question with a Likert Scale or a Visual Analog Scale (VAS) response adequately measures current anxiety. Consecutive English-speaking adult women attending a dedicated breast clinic in a major Australian city were invited to complete a demographic questionnaire, the State Trait Anxiety Inventory (STAI), and a single question with a five-point Likert Scale response and a VAS in random order. Only women who completed the STAI were included in analyses. Four hundred of 497 (80%) eligible women agreed to participate. Both measures were adequate predictors of the STAI score; correlation with STAI was 0.78 (95% confidence interval [CI] 0.73-0.82) for the VAS and 0.75 (95% CI 0.70-0.79) for the Likert Scale. However, 11% of women incorrectly completed the VAS limiting its usefulness. A single question with either a Likert Scale or VAS response may be an adequate replacement for the STAI. Both measures quickly and easily assess anxiety and may be useful for research purposes when researchers have very limited time or questionnaire space or need to reduce the burden on participants of completing many measures.

  18. Current strategies for the restoration of adequate lordosis during lumbar fusion.

    Science.gov (United States)

    Barrey, Cédric; Darnis, Alice

    2015-01-18

    Not restoring the adequate lumbar lordosis during lumbar fusion surgery may result in mechanical low back pain, sagittal unbalance and adjacent segment degeneration. The objective of this work is to describe the current strategies and concepts for restoration of adequate lordosis during fusion surgery. Theoretical lordosis can be evaluated from the measurement of the pelvic incidence and from the analysis of spatial organization of the lumbar spine with 2/3 of the lordosis given by the L4-S1 segment and 85% by the L3-S1 segment. Technical aspects involve patient positioning on the operating table, release maneuvers, type of instrumentation used (rod, screw-rod connection, interbody cages), surgical sequence and the overall surgical strategy. Spinal osteotomies may be required in case of fixed kyphotic spine. AP combined surgery is particularly efficient in restoring lordosis at L5-S1 level and should be recommended. Finally, not one but several strategies may be used to achieve the need for restoration of adequate lordosis during fusion surgery.

  19. Current strategies for the restoration of adequate lordosis during lumbar fusion

    Science.gov (United States)

    Barrey, Cédric; Darnis, Alice

    2015-01-01

    Not restoring the adequate lumbar lordosis during lumbar fusion surgery may result in mechanical low back pain, sagittal unbalance and adjacent segment degeneration. The objective of this work is to describe the current strategies and concepts for restoration of adequate lordosis during fusion surgery. Theoretical lordosis can be evaluated from the measurement of the pelvic incidence and from the analysis of spatial organization of the lumbar spine with 2/3 of the lordosis given by the L4-S1 segment and 85% by the L3-S1 segment. Technical aspects involve patient positioning on the operating table, release maneuvers, type of instrumentation used (rod, screw-rod connection, interbody cages), surgical sequence and the overall surgical strategy. Spinal osteotomies may be required in case of fixed kyphotic spine. AP combined surgery is particularly efficient in restoring lordosis at L5-S1 level and should be recommended. Finally, not one but several strategies may be used to achieve the need for restoration of adequate lordosis during fusion surgery. PMID:25621216

  20. Robust Multiobjective Controllability of Complex Neuronal Networks.

    Science.gov (United States)

    Tang, Yang; Gao, Huijun; Du, Wei; Lu, Jianquan; Vasilakos, Athanasios V; Kurths, Jurgen

    2016-01-01

    This paper addresses robust multiobjective identification of driver nodes in the neuronal network of a cat's brain, in which uncertainties in determination of driver nodes and control gains are considered. A framework for robust multiobjective controllability is proposed by introducing interval uncertainties and optimization algorithms. By appropriate definitions of robust multiobjective controllability, a robust nondominated sorting adaptive differential evolution (NSJaDE) is presented by means of the nondominated sorting mechanism and the adaptive differential evolution (JaDE). The simulation experimental results illustrate the satisfactory performance of NSJaDE for robust multiobjective controllability, in comparison with six statistical methods and two multiobjective evolutionary algorithms (MOEAs): nondominated sorting genetic algorithms II (NSGA-II) and nondominated sorting composite differential evolution. It is revealed that the existence of uncertainties in choosing driver nodes and designing control gains heavily affects the controllability of neuronal networks. We also unveil that driver nodes play a more drastic role than control gains in robust controllability. The developed NSJaDE and obtained results will shed light on the understanding of robustness in controlling realistic complex networks such as transportation networks, power grid networks, biological networks, etc.

  1. Towards distortion-free robust image authentication

    International Nuclear Information System (INIS)

    Coltuc, D

    2007-01-01

    This paper investigates a general framework for distortion-free robust image authentication by multiple marking. First, by robust watermarking a subsampled version of image edges is embedded. Then, by reversible watermarking the information needed to recover the original image is inserted, too. The hiding capacity of the reversible watermarking is the essential requirement for this approach. Thus in case of no attacks not only image is authenticated but also the original is exactly recovered. In case of attacks, reversibility is lost, but image can still be authenticated. Preliminary results providing very good robustness against JPEG compression are presented

  2. Robust statistics and geochemical data analysis

    International Nuclear Information System (INIS)

    Di, Z.

    1987-01-01

    Advantages of robust procedures over ordinary least-squares procedures in geochemical data analysis is demonstrated using NURE data from the Hot Springs Quadrangle, South Dakota, USA. Robust principal components analysis with 5% multivariate trimming successfully guarded the analysis against perturbations by outliers and increased the number of interpretable factors. Regression with SINE estimates significantly increased the goodness-of-fit of the regression and improved the correspondence of delineated anomalies with known uranium prospects. Because of the ubiquitous existence of outliers in geochemical data, robust statistical procedures are suggested as routine procedures to replace ordinary least-squares procedures

  3. Danish Requirements for Robustness of Structures

    DEFF Research Database (Denmark)

    Sørensen, John Dalsgaard; Christensen, H. H.

    2006-01-01

    Increased use of advanced types of structures with limited redundancy and serious failure consequences combined with strengthened requirements to efficiency in design and execution as well as increased risk of human errors necessitates requirements for the robustness of new structures, essential....... This paper describes the background of the revised robustness requirements implemented in the Danish Code of Practice for Safety of Structures in 2003 [1, 2, 3]. According to the Danish design rules robustness shall be documented for all structures where consequences of failure are serious. This paper...

  4. Robust Structured Control Design via LMI Optimization

    DEFF Research Database (Denmark)

    Adegas, Fabiano Daher; Stoustrup, Jakob

    2011-01-01

    This paper presents a new procedure for discrete-time robust structured control design. Parameter-dependent nonconvex conditions for stabilizable and induced L2-norm performance controllers are solved by an iterative linear matrix inequalities (LMI) optimization. A wide class of controller...... structures including decentralized of any order, fixed-order dynamic output feedback, static output feedback can be designed robust to polytopic uncertainties. Stability is proven by a parameter-dependent Lyapunov function. Numerical examples on robust stability margins shows that the proposed procedure can...

  5. Evolution of robust and efficient system topologies.

    Science.gov (United States)

    Netotea, Sergiu; Pongor, Sándor

    2006-12-01

    Mutation/selection algorithms were applied to increase the efficiency and the robustness of sparse random networks. Selection for better efficiency leads to the well-known star topology, while selection for robustness only results in a relatively dense core and a small periphery. Concomitant selection for both efficiency and robustness leads to networks with intermittent center/periphery values. Networks evolving under multiple attack regimes develop distinct topologies with larger cores, and are characterized by parameter distributions different from those developing under single-attack regimes.

  6. A Survey on Robustness in Railway Planning

    DEFF Research Database (Denmark)

    Lusby, Richard Martin; Larsen, Jesper; Bull, Simon Henry

    2018-01-01

    Planning problems in passenger railway range from long term strategic decision making to the detailed planning of operations.Operations research methods have played an increasing role in this planning process. However, recently more attention has been given to considerations of robustness...... with a disruption such as delay or failure. This has resulted in more attention given to the inclusion of robustness measures and objectives in individual planning problems, and to the providing of tools to ensure operations continue under disrupted situations. In this paper we survey the literature on robustness...

  7. Robust recognition via information theoretic learning

    CERN Document Server

    He, Ran; Yuan, Xiaotong; Wang, Liang

    2014-01-01

    This Springer Brief represents a comprehensive review of information theoretic methods for robust recognition. A variety of information theoretic methods have been proffered in the past decade, in a large variety of computer vision applications; this work brings them together, attempts to impart the theory, optimization and usage of information entropy.The?authors?resort to a new information theoretic concept, correntropy, as a robust measure and apply it to solve robust face recognition and object recognition problems. For computational efficiency,?the brief?introduces the additive and multip

  8. Design Robust Controller for Rotary Kiln

    Directory of Open Access Journals (Sweden)

    Omar D. Hernández-Arboleda

    2013-11-01

    Full Text Available This paper presents the design of a robust controller for a rotary kiln. The designed controller is a combination of a fractional PID and linear quadratic regulator (LQR, these are not used to control the kiln until now, in addition robustness criteria are evaluated (gain margin, phase margin, strength gain, rejecting high frequency noise and sensitivity applied to the entire model (controller-plant, obtaining good results with a frequency range of 0.020 to 90 rad/s, which contributes to the robustness of the system.

  9. Assessment of Process Robustness for Mass Customization

    DEFF Research Database (Denmark)

    Nielsen, Kjeld; Brunø, Thomas Ditlev

    2013-01-01

    robustness and their capability to develop it. Through literature study and analysis of robust process design characteristics a number of metrics are described which can be used for assessment. The metrics are evaluated and analyzed to be applied as KPI’s to help MC companies prioritize efforts in business......In mass customization, the capability Robust Process Design defined as the ability to reuse or recombine existing organizational and value-chain resources is essential to deliver a high variety cost effectively. We argue that there is a need for methods which can assess a company’s process...

  10. Efficient reanalysis techniques for robust topology optimization

    DEFF Research Database (Denmark)

    Amir, Oded; Sigmund, Ole; Lazarov, Boyan Stefanov

    2012-01-01

    The article focuses on the reduction of the computational effort involved in robust topology optimization procedures. The performance of structures designed by means of topology optimization may be seriously degraded due to fabrication errors. Robust formulations of the optimization problem were...... shown to yield optimized designs that are tolerant with respect to such manufacturing uncertainties. The main drawback of such procedures is the added computational cost associated with the need to evaluate a set of designs by performing multiple finite element analyses. In this article, we propose...... efficient robust topology optimization procedures based on reanalysis techniques. The approach is demonstrated on two compliant mechanism design problems where robust design is achieved by employing either a worst case formulation or a stochastic formulation. It is shown that the time spent on finite...

  11. Robust Tracking Control for a Piezoelectric Actuator

    National Research Council Canada - National Science Library

    Salah, M; McIntyre, M; Dawson, D; Wagner, J

    2006-01-01

    In this paper, a hysteresis model-based nonlinear robust controller is developed for a piezoelectric actuator, utilizing a Lyapunov-based stability analysis, which ensures that a desired displacement...

  12. Robust nonlinear control of vectored thrust aircraft

    Science.gov (United States)

    Doyle, John C.; Murray, Richard; Morris, John

    1993-01-01

    An interdisciplinary program in robust control for nonlinear systems with applications to a variety of engineering problems is outlined. Major emphasis will be placed on flight control, with both experimental and analytical studies. This program builds on recent new results in control theory for stability, stabilization, robust stability, robust performance, synthesis, and model reduction in a unified framework using Linear Fractional Transformations (LFT's), Linear Matrix Inequalities (LMI's), and the structured singular value micron. Most of these new advances have been accomplished by the Caltech controls group independently or in collaboration with researchers in other institutions. These recent results offer a new and remarkably unified framework for all aspects of robust control, but what is particularly important for this program is that they also have important implications for system identification and control of nonlinear systems. This combines well with Caltech's expertise in nonlinear control theory, both in geometric methods and methods for systems with constraints and saturations.

  13. Multifidelity Robust Aeroelastic Design, Phase I

    Data.gov (United States)

    National Aeronautics and Space Administration — Nielsen Engineering & Research (NEAR) proposes a new method to generate mathematical models of wind-tunnel models and flight vehicles for robust aeroelastic...

  14. Robust entangled qutrit states in atmospheric turbulence

    CSIR Research Space (South Africa)

    Brunner, T

    2013-06-01

    Full Text Available The entangled quantum state of a photon pair propagating through atmospheric turbulence suffers decay of entanglement due to the scintillation it experiences. Here we investigate the robustness against this decay for different qutrit states. We use...

  15. Design principles for robust oscillatory behavior.

    Science.gov (United States)

    Castillo-Hair, Sebastian M; Villota, Elizabeth R; Coronado, Alberto M

    2015-09-01

    Oscillatory responses are ubiquitous in regulatory networks of living organisms, a fact that has led to extensive efforts to study and replicate the circuits involved. However, to date, design principles that underlie the robustness of natural oscillators are not completely known. Here we study a three-component enzymatic network model in order to determine the topological requirements for robust oscillation. First, by simulating every possible topological arrangement and varying their parameter values, we demonstrate that robust oscillators can be obtained by augmenting the number of both negative feedback loops and positive autoregulations while maintaining an appropriate balance of positive and negative interactions. We then identify network motifs, whose presence in more complex topologies is a necessary condition for obtaining oscillatory responses. Finally, we pinpoint a series of simple architectural patterns that progressively render more robust oscillators. Together, these findings can help in the design of more reliable synthetic biomolecular networks and may also have implications in the understanding of other oscillatory systems.

  16. Robust resource allocation in future wireless networks

    CERN Document Server

    Parsaeefard, Saeedeh; Mokari, Nader

    2017-01-01

    This book presents state-of-the-art research on robust resource allocation in current and future wireless networks. The authors describe the nominal resource allocation problems in wireless networks and explain why introducing robustness in such networks is desirable. Then, depending on the objectives of the problem, namely maximizing the social utility or the per-user utility, cooperative or competitive approaches are explained and their corresponding robust problems are considered in detail. For each approach, the costs and benefits of robust schemes are discussed and the algorithms for reducing their costs and improving their benefits are presented. Considering the fact that such problems are inherently non-convex and intractable, a taxonomy of different relaxation techniques is presented, and applications of such techniques are shown via several examples throughout the book. Finally, the authors argue that resource allocation continues to be an important issue in future wireless networks, and propose spec...

  17. Robust logic gates and realistic quantum computation

    International Nuclear Information System (INIS)

    Xiao Li; Jones, Jonathan A.

    2006-01-01

    The composite rotation approach has been used to develop a range of robust quantum logic gates, including single qubit gates and two qubit gates, which are resistant to systematic errors in their implementation. Single qubit gates based on the BB1 family of composite rotations have been experimentally demonstrated in a variety of systems, but little study has been made of their application in extended computations, and there has been no experimental study of the corresponding robust two qubit gates to date. Here we describe an application of robust gates to nuclear magnetic resonance studies of approximate quantum counting. We find that the BB1 family of robust gates is indeed useful, but that the related NB1, PB1, B4, and P4 families of tailored logic gates are less useful than initially expected

  18. Robust control of robots fault tolerant approaches

    CERN Document Server

    Siqueira, Adriano A G; Bergerman, Marcel

    2014-01-01

    Bridging the divide between robust control theory and its application, this volume focuses on robotic manipulators and illustrates the mathematical concepts through experimental results in reproducible detail, obtained with a two-manipulator system.

  19. Robust Satellite Communications Under Hostile Interference

    Science.gov (United States)

    2016-05-20

    or elimination of required feedback signals, jammer herding, multi-source signalling, and interference alignment . In the case of the replace with...AFRL-RV-PS- AFRL-RV-PS- TR-2016-0079 TR-2016-0079 ROBUST SATELLITE COMMUNICATIONS UNDER HOSTILE INTERFERENCE Marc Lichtman and Jeffrey Reed...FA9453-14-1-0222 Robust Satellite Communications Under Hostile Interference 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 62601F 6. AUTHOR(S) 5d

  20. Three Contributions to Robust Regression Diagnostics

    Czech Academy of Sciences Publication Activity Database

    Kalina, Jan

    2015-01-01

    Roč. 11, č. 2 (2015), s. 69-78 ISSN 1336-9180 Grant - others:GA ČR(CZ) GA13-01930S; Nadační fond na podporu vědy(CZ) Neuron Institutional support: RVO:67985807 Keywords : robust regression * robust econometrics * hypothesis testing Subject RIV: BA - General Mathematics http://www.degruyter.com/view/j/jamsi.2015.11.issue-2/jamsi-2015-0013/jamsi-2015-0013. xml ?format=INT

  1. Framework for Robustness Assessment of Timber Structures

    DEFF Research Database (Denmark)

    Sørensen, John Dalsgaard

    2011-01-01

    This paper presents a theoretical framework for the design and analysis of robustness of timber structures. This is actualized by a more4 frequent use of advanced types of timber structures with limited redundancy and serious consequences in the case of failure. Combined with increased requirements...... are not specified in detail, which makes the practical use difficult. This paper describes a theoretical and risk based framework to form the basis for quantification of robustness and for pre-normative guidelines....

  2. Robust Planning for Effects-Based Operations

    Science.gov (United States)

    2006-06-01

    hypothesis or options [56]. Recency tends to trump primacy in complex problems. "* Elimination by aspect: When trying to choose among several options...THESIS 4. TITLE AND SUBTITLE 5. FUNDING NUMBERS ROBUST PLANNING FOR EFFECTS BASED OPERATIONS 6. AUTHOR(S) 2D LT BRYANT CORBAN H 7. PERFORMING ORGANIZATION...EG) escribed by ANSI Std. 239.18 DesgJned using Perform Pro, WHS/DIOR, Oct 94 Robust Planning for Effects -Based Operations by Corban Harrell Bryant

  3. Antecedents and Dimensions of Supply Chain Robustness

    OpenAIRE

    Durach, Christian F.; Wieland, Andreas; Machuca, Jose A.D.

    2015-01-01

    Purpose – The purpose of this paper is to provide groundwork for an emerging theory of supply chain robustness – which has been conceptualized as a dimension of supply chain resilience – through reviewing and synthesizing related yet disconnected studies. The paper develops a formal definition of supply chain robustness to build a framework that captures the dimensions, antecedents and moderators of the construct as discussed in the literature. Design/methodology/approach – The...

  4. Adaptive Critic Nonlinear Robust Control: A Survey.

    Science.gov (United States)

    Wang, Ding; He, Haibo; Liu, Derong

    2017-10-01

    Adaptive dynamic programming (ADP) and reinforcement learning are quite relevant to each other when performing intelligent optimization. They are both regarded as promising methods involving important components of evaluation and improvement, at the background of information technology, such as artificial intelligence, big data, and deep learning. Although great progresses have been achieved and surveyed when addressing nonlinear optimal control problems, the research on robustness of ADP-based control strategies under uncertain environment has not been fully summarized. Hence, this survey reviews the recent main results of adaptive-critic-based robust control design of continuous-time nonlinear systems. The ADP-based nonlinear optimal regulation is reviewed, followed by robust stabilization of nonlinear systems with matched uncertainties, guaranteed cost control design of unmatched plants, and decentralized stabilization of interconnected systems. Additionally, further comprehensive discussions are presented, including event-based robust control design, improvement of the critic learning rule, nonlinear H ∞ control design, and several notes on future perspectives. By applying the ADP-based optimal and robust control methods to a practical power system and an overhead crane plant, two typical examples are provided to verify the effectiveness of theoretical results. Overall, this survey is beneficial to promote the development of adaptive critic control methods with robustness guarantee and the construction of higher level intelligent systems.

  5. HIGHLY ROBUST METHODS IN DATA MINING

    Directory of Open Access Journals (Sweden)

    Jan Kalina

    2013-05-01

    Full Text Available This paper is devoted to highly robust methods for information extraction from data, with a special attention paid to methods suitable for management applications. The sensitivity of availabledata mining methods to the presence of outlying measurements in the observed data is discussed as a major drawback of available data mining methods. The paper proposes several newhighly robustmethods for data mining, which are based on the idea of implicit weighting of individual data values.Particularly it propose a novel robust method of hierarchical cluster analysis, which is a popular data mining method of unsupervised learning. Further, a robust method for estimating parameters in thelogistic regression was proposed. This idea is extended to a robust multinomial logistic classification analysis. Finally, the sensitivity of neural networks to the presence of noise and outlying measurements in the data was discussed. The method for robust training of neural networks for the task of function approximation, which has the form of a robust estimator in nonlinear regression, was proposed.

  6. The Rationality of Four Metrics of Network Robustness: A Viewpoint of Robust Growth of Generalized Meshes.

    Directory of Open Access Journals (Sweden)

    Xiaofan Yang

    Full Text Available There are quite a number of different metrics of network robustness. This paper addresses the rationality of four metrics of network robustness (the algebraic connectivity, the effective resistance, the average edge betweenness, and the efficiency by investigating the robust growth of generalized meshes (GMs. First, a heuristic growth algorithm (the Proximity-Growth algorithm is proposed. The resulting proximity-optimal GMs are intuitively robust and hence are adopted as the benchmark. Then, a generalized mesh (GM is grown up by stepwise optimizing a given measure of network robustness. The following findings are presented: (1 The algebraic connectivity-optimal GMs deviate quickly from the proximity-optimal GMs, yielding a number of less robust GMs. This hints that the rationality of the algebraic connectivity as a measure of network robustness is still in doubt. (2 The effective resistace-optimal GMs and the average edge betweenness-optimal GMs are in line with the proximity-optimal GMs. This partly justifies the two quantities as metrics of network robustness. (3 The efficiency-optimal GMs deviate gradually from the proximity-optimal GMs, yielding some less robust GMs. This suggests the limited utility of the efficiency as a measure of network robustness.

  7. Establishing adequate conditions for mercury determination in environmental samples by INAA

    International Nuclear Information System (INIS)

    Perez, Caroline; Santos, Eliane C.; Saiki, Mitiko

    2017-01-01

    Mercury (Hg) is a toxic element released into the environment mainly by anthropic activities. Consequently, the improvement for Hg determination in environmental samples is of great interest. Instrumental Neutron Activation Analysis (INAA) is considered an adequate method to determine several elements. However, Hg determination by INAA is often hampered by its volatility, which causes losses. The aim of this study was to establish adequate irradiation conditions for Hg determination in environmental samples by INAA. The following parameters were evaluated: irradiation time, container for irradiation and spectral gamma ray interferences. For the study, aliquots of certified reference materials (CRMs) and tree bark samples were irradiated together with Hg synthetic standard at the IEA-R1 nuclear research reactor. Gamma ray activities of 1 97 Hg and 203 Hg were measured in a spectrometer coupled to a HGe detector. Results obtained indicated that polyethylene capsules or envelopes can be used as container for sample irradiation and the Hg impurities in these containers were negligible. Irradiation time of one hour was adequate for Hg determination and in long irradiations of 8 h problems of spectral interference of 198 Au and 75 Se were observed. In addition, Hg loss during the irradiation of 1 h and after irradiation was not observed. Quality control of Hg results, obtained in the CRMs analyses using one hour of irradiation, indicated good precision and accuracy with |Z score| < 2. The experimental conditions established in this study were applied to tree bark samples. Detection limits for Hg of these analyses were between 0.14 and 1.9 μg g -1 . (author)

  8. Are the current Australian sun exposure guidelines effective in maintaining adequate levels of 25-hydroxyvitamin D?

    Science.gov (United States)

    Kimlin, Michael; Sun, Jiandong; Sinclair, Craig; Heward, Sue; Hill, Jane; Dunstone, Kimberley; Brodie, Alison

    2016-01-01

    An adequate vitamin D status, as measured by serum 25-hydroxyvitamin D (25(OH)D) concentration, is important in humans for maintenance of healthy bones and muscle function. Serum 25(OH)D concentration was assessed in participants from Melbourne, Australia (37.81S, 144.96E), who were provided with the current Australian guidelines on sun exposure for 25(OH)D adequacy (25(OH)D ≥50 nmol/L). Participants were interviewed in February (summer, n=104) and August (winter, n=99) of 2013. Serum 25(OH)D concentration was examined as a function of measures of sun exposure and sun protection habits with control of key characteristics such as dietary intake of vitamin D, body mass index (BMI) and skin colour, that may modify this relationship. The mean 25(OH)D concentration in participants who complied with the current sun exposure guidelines was 67.3 nmol/L in summer and 41.9 nmol/L in winter. At the end of the study, 69.3% of participants who complied with the summer sun exposure guidelines were 25(OH)D adequate, while only 27.6% of participants who complied with the winter sun exposure guidelines were 25(OH)D adequate at the end of the study. The results suggest that the current Australian guidelines for sun exposure for 25(OH)D adequacy are effective for most in summer and ineffective for most in winter. This article is part of a Special Issue entitled '17th Vitamin D Workshop'. Copyright © 2015 Elsevier Ltd. All rights reserved.

  9. Towards {sup 31}Mg-β-NMR resonance linewidths adequate for applications in magnesium chemistry

    Energy Technology Data Exchange (ETDEWEB)

    Stachura, M., E-mail: mstachura@triumf.ca [TRIUMF (Canada); McFadden, R. M. L. [University of British Columbia, Chemistry Department (Canada); Chatzichristos, A.; Dehn, M. H. [University of British Columbia, Department of Physics and Astronomy (Canada); Gottberg, A. [TRIUMF (Canada); Hemmingsen, L. [Københavns Universitet Universitetsparken 5, Kemisk Institut (Denmark); Jancso, A. [University of Szeged, Department of Inorganic and Analytical Chemistry (Hungary); Karner, V. L. [University of British Columbia, Chemistry Department (Canada); Kiefl, R. F. [University of British Columbia, Department of Physics and Astronomy (Canada); Larsen, F. H. [Københavns Universitet Rolighedsvej 26, Institut for Fødevarevidenskab (Denmark); Lassen, J.; Levy, C. D. P.; Li, R. [TRIUMF (Canada); MacFarlane, W. A. [University of British Columbia, Chemistry Department (Canada); Morris, G. D. [TRIUMF (Canada); Pallada, S. [CERN (Switzerland); Pearson, M. R. [TRIUMF (Canada); Szunyogh, D.; Thulstrup, P. W. [Københavns Universitet Universitetsparken 5, Kemisk Institut (Denmark); Voss, A. [University of Jyväskylä, Department of Physics (Finland)

    2017-11-15

    The span of most chemical shifts recorded in conventional {sup 25}Mg-NMR spectroscopy is ~ 100 ppm. Accordingly, linewidths of ~ 10 ppm or better are desirable to achieve adequate resolution for applications in chemistry. Here we present first high-field {sup 31}Mg- β-NMR measurements of {sup 31}Mg{sup +} ions implanted into a MgO single crystal carried out at the ISAC facility at TRIUMF. The resonances recorded at 2.5 T and 3.5 T show strong linewidth dependency on the applied RF power, ranging from ~ 419 ppm for the highest RF power down to ~ 48 ppm for the lowest one.

  10. Prochaotic tourism development pressure on coastal habitats adequate evaluation case study in Sulina, Romnia

    Directory of Open Access Journals (Sweden)

    DOROFTEI Mihai

    2016-12-01

    Full Text Available On the coastal areas, the pressure of touristic development upon natural areas is increasing and interfering with main purposes of Natura 2000 sites designation. Therefore the habitats tendency, adequate for species development, is in regression as far as areas size and homogeneity are concerned. In this respect, a case study is presented for the Black Sea’s north-western littoral, in Sulina locality, Romania. The present paper was elaborated in conformity with Ministry Order 19/2010 for the Methodological Guide with regard to the adequate evaluation (A.E. of the effect of potential plans or projects on protected natural areas of community importance. The case study is an investment project called lina eac arrangeen. Its objective was to develop a plot for the beach area’s tourist infrastructure in order to provide services to the public. The cumulative impact of the existing project may affect the coastal habitats (1210, 1310, 1410, 2110 and 2160 and Natura 2000 site integrity (ROSCI0065 Danube Delta. Regarding these habitats types, conservation value, criterion of representativeness and functions in concern with possibilities for restoration are analyzed. At present, the studied emplacement is mainly affected by the anthropic interventions, having the aspect of a degraded natural area. In addition, conservation measures are described, which were elaborated in accordance with both the national legislation and by consulting the management plans of certain protected natural areas from abroad, which contain habitats characteristic to the marine coast and sandpits within their perimeter.

  11. Incentives for an adequate, economic and reliable Swiss transmission grid. Final version

    International Nuclear Information System (INIS)

    Twomey, P.; Neuhoff, K.; Newbery, D.

    2006-11-01

    This comprehensive final report for the Swiss Federal Office of Energy (SFOE) discusses incentives necessary for the implementation of an adequate, economic and reliable Swiss electricity transmission grid. As Switzerland moves towards a more liberalised and competitive electricity market, an essential task of policy makers will be to ensure that incentives are in place for the construction, maintenance and operation of adequate, economic and reliable transmission infrastructure. As well as continuing to serve the domestic market, the location of Switzerland at the centre of Europe also means that policy should embrace opportunities in servicing the developing European Internal Market by providing transit and other services. Topics discussed include the economic evaluation of transmission investment proposals, regulated transmission investment, investments in transmission lines by power merchants, power auctions and congestion management as well as inter-TSO compensation mechanisms. European regulations and practice are discussed as are access questions and transmission charges. Developments in interconnection management and harmonisation are examined. The particular characteristics of the Swiss energy system, its prices and its legal frameworks are discussed. Cross-border trading and security of supply are also discussed

  12. Are we failing to document adequate smoking histories? A brief review 1999-2009.

    Science.gov (United States)

    Self, Timothy H; Wallace, Jessica L; Gray, Lori Arnold; Usery, Justin B; Finch, Christopher K; Deaton, Paul R

    2010-07-01

    Documenting a detailed smoking history is of obvious importance. Failure to adequately document the smoking history may result in the misdiagnosis and management of asthma, and may be associated with a deficiency of care in patients with cardiovascular disease and several other common diseases. The purpose of this article is to review the evidence over the past decade that demonstrates inadequate documentation of smoking history. A literature search of English language journals from 1999 to 2009 was completed using several databases, including PubMed, MEDLINE, EMBASE, and SCOPUS. Fourteen studies demonstrated inadequate documentation of smoking histories by primary care clinicians, specialists, residents, and medical students. Failure to document smoking histories was observed in patients with conditions such as heart failure, coronary artery disease, and asthma. Electronic decision support systems and simple medical record reminders were effective in improving the documentation of smoking histories. Failure to adequately document the smoking history appears to be common. Strategies such as electronic decision support systems are needed to correct this problem in order for patients to receive optimal therapy for their appropriate diagnoses.

  13. Incentives for an adequate, economic and reliable Swiss transmission grid. Final version

    Energy Technology Data Exchange (ETDEWEB)

    Twomey, P.; Neuhoff, K.; Newbery, D.

    2006-11-15

    This comprehensive final report for the Swiss Federal Office of Energy (SFOE) discusses incentives necessary for the implementation of an adequate, economic and reliable Swiss electricity transmission grid. As Switzerland moves towards a more liberalised and competitive electricity market, an essential task of policy makers will be to ensure that incentives are in place for the construction, maintenance and operation of adequate, economic and reliable transmission infrastructure. As well as continuing to serve the domestic market, the location of Switzerland at the centre of Europe also means that policy should embrace opportunities in servicing the developing European Internal Market by providing transit and other services. Topics discussed include the economic evaluation of transmission investment proposals, regulated transmission investment, investments in transmission lines by power merchants, power auctions and congestion management as well as inter-TSO compensation mechanisms. European regulations and practice are discussed as are access questions and transmission charges. Developments in interconnection management and harmonisation are examined. The particular characteristics of the Swiss energy system, its prices and its legal frameworks are discussed. Cross-border trading and security of supply are also discussed

  14. The comparison of robust partial least squares regression with robust principal component regression on a real

    Science.gov (United States)

    Polat, Esra; Gunay, Suleyman

    2013-10-01

    One of the problems encountered in Multiple Linear Regression (MLR) is multicollinearity, which causes the overestimation of the regression parameters and increase of the variance of these parameters. Hence, in case of multicollinearity presents, biased estimation procedures such as classical Principal Component Regression (CPCR) and Partial Least Squares Regression (PLSR) are then performed. SIMPLS algorithm is the leading PLSR algorithm because of its speed, efficiency and results are easier to interpret. However, both of the CPCR and SIMPLS yield very unreliable results when the data set contains outlying observations. Therefore, Hubert and Vanden Branden (2003) have been presented a robust PCR (RPCR) method and a robust PLSR (RPLSR) method called RSIMPLS. In RPCR, firstly, a robust Principal Component Analysis (PCA) method for high-dimensional data on the independent variables is applied, then, the dependent variables are regressed on the scores using a robust regression method. RSIMPLS has been constructed from a robust covariance matrix for high-dimensional data and robust linear regression. The purpose of this study is to show the usage of RPCR and RSIMPLS methods on an econometric data set, hence, making a comparison of two methods on an inflation model of Turkey. The considered methods have been compared in terms of predictive ability and goodness of fit by using a robust Root Mean Squared Error of Cross-validation (R-RMSECV), a robust R2 value and Robust Component Selection (RCS) statistic.

  15. A Unifying Mathematical Framework for Genetic Robustness, Environmental Robustness, Network Robustness and their Trade-off on Phenotype Robustness in Biological Networks Part I: Gene Regulatory Networks in Systems and Evolutionary Biology.

    Science.gov (United States)

    Chen, Bor-Sen; Lin, Ying-Po

    2013-01-01

    Robust stabilization and environmental disturbance attenuation are ubiquitous systematic properties observed in biological systems at different levels. The underlying principles for robust stabilization and environmental disturbance attenuation are universal to both complex biological systems and sophisticated engineering systems. In many biological networks, network robustness should be enough to confer intrinsic robustness in order to tolerate intrinsic parameter fluctuations, genetic robustness for buffering genetic variations, and environmental robustness for resisting environmental disturbances. With this, the phenotypic stability of biological network can be maintained, thus guaranteeing phenotype robustness. This paper presents a survey on biological systems and then develops a unifying mathematical framework for investigating the principles of both robust stabilization and environmental disturbance attenuation in systems and evolutionary biology. Further, from the unifying mathematical framework, it was discovered that the phenotype robustness criterion for biological networks at different levels relies upon intrinsic robustness + genetic robustness + environmental robustness ≦ network robustness. When this is true, the phenotype robustness can be maintained in spite of intrinsic parameter fluctuations, genetic variations, and environmental disturbances. Therefore, the trade-offs between intrinsic robustness, genetic robustness, environmental robustness, and network robustness in systems and evolutionary biology can also be investigated through their corresponding phenotype robustness criterion from the systematic point of view.

  16. It's Gettin' Hot in Here: Breeding Robust Yeast Starter Cultures for Cocoa Fermentation.

    Science.gov (United States)

    Papalexandratou, Zoi; Nielsen, Dennis S

    2016-03-01

    Cocoa beans have to undergo post-harvest fermentation and drying to develop the typical 'cocoa flavor' associated with chocolate. Yeasts play a pivotal role during the fermentation but are generally outcompeted early in the process. Meersman and colleagues describe an elegant breeding-based approach to generate robust yeast starter cultures for cocoa fermentation. Copyright © 2016 Elsevier Ltd. All rights reserved.

  17. Information theory perspective on network robustness

    Energy Technology Data Exchange (ETDEWEB)

    Schieber, Tiago A. [Departmento de Engenharia de Produção, Universidade Federal de Minas Gerais, Belo Horizonte, MG (Brazil); Industrial and Systems Engineering, University of Florida, Gainesville, FL (United States); Carpi, Laura [Departament de Física i Enginyeria Nuclear, Universitat Politècnica de Catalunya, Colom 11, Terrassa, 08222, Barcelona (Spain); Frery, Alejandro C. [Laboratório de Computação Científica e Análise Numérica (LaCCAN), Universidade Federal de Alagoas, Maceió, Alagoas (Brazil); Rosso, Osvaldo A. [Instituto de Física, Universidade Federal de Alagoas, Maceió, Alagoas (Brazil); Instituto Tecnológico de Buenos Aires (ITBA), Ciudad Autónoma de Buenos Aires (Argentina); Pardalos, Panos M. [Industrial and Systems Engineering, University of Florida, Gainesville, FL (United States); Ravetti, Martín G., E-mail: martin.ravetti@dep.ufmg.br [Departmento de Engenharia de Produção, Universidade Federal de Minas Gerais, Belo Horizonte, MG (Brazil); Departament de Física Fonamental, Universitat de Barcelona, Barcelona (Spain)

    2016-01-28

    A crucial challenge in network theory is the study of the robustness of a network when facing a sequence of failures. In this work, we propose a dynamical definition of network robustness based on Information Theory, that considers measurements of the structural changes caused by failures of the network's components. Failures are defined here as a temporal process defined in a sequence. Robustness is then evaluated by measuring dissimilarities between topologies after each time step of the sequence, providing a dynamical information about the topological damage. We thoroughly analyze the efficiency of the method in capturing small perturbations by considering different probability distributions on networks. In particular, we find that distributions based on distances are more consistent in capturing network structural deviations, as better reflect the consequences of the failures. Theoretical examples and real networks are used to study the performance of this methodology. - Highlights: • A novel methodology to measure the robustness of a network to component failure or targeted attacks is proposed. • The use of the network's distance PDF allows a precise analysis. • The method provides a dynamic robustness profile showing the response of the topology to each failure event. • The measure is capable to detect network's critical elements.

  18. Non-Hermitian bidirectional robust transport

    Science.gov (United States)

    Longhi, Stefano

    2017-01-01

    Transport of quantum or classical waves in open systems is known to be strongly affected by non-Hermitian terms that arise from an effective description of system-environment interaction. A simple and paradigmatic example of non-Hermitian transport, originally introduced by Hatano and Nelson two decades ago [N. Hatano and D. R. Nelson, Phys. Rev. Lett. 77, 570 (1996), 10.1103/PhysRevLett.77.570], is the hopping dynamics of a quantum particle on a one-dimensional tight-binding lattice in the presence of an imaginary vectorial potential. The imaginary gauge field can prevent Anderson localization via non-Hermitian delocalization, opening up a mobility region and realizing robust transport immune to disorder and backscattering. Like for robust transport of topologically protected edge states in quantum Hall and topological insulator systems, non-Hermitian robust transport in the Hatano-Nelson model is unidirectional. However, there is not any physical impediment to observe robust bidirectional non-Hermitian transport. Here it is shown that in a quasi-one-dimensional zigzag lattice, with non-Hermitian (imaginary) hopping amplitudes and a synthetic gauge field, robust transport immune to backscattering can occur bidirectionally along the lattice.

  19. Information theory perspective on network robustness

    International Nuclear Information System (INIS)

    Schieber, Tiago A.; Carpi, Laura; Frery, Alejandro C.; Rosso, Osvaldo A.; Pardalos, Panos M.; Ravetti, Martín G.

    2016-01-01

    A crucial challenge in network theory is the study of the robustness of a network when facing a sequence of failures. In this work, we propose a dynamical definition of network robustness based on Information Theory, that considers measurements of the structural changes caused by failures of the network's components. Failures are defined here as a temporal process defined in a sequence. Robustness is then evaluated by measuring dissimilarities between topologies after each time step of the sequence, providing a dynamical information about the topological damage. We thoroughly analyze the efficiency of the method in capturing small perturbations by considering different probability distributions on networks. In particular, we find that distributions based on distances are more consistent in capturing network structural deviations, as better reflect the consequences of the failures. Theoretical examples and real networks are used to study the performance of this methodology. - Highlights: • A novel methodology to measure the robustness of a network to component failure or targeted attacks is proposed. • The use of the network's distance PDF allows a precise analysis. • The method provides a dynamic robustness profile showing the response of the topology to each failure event. • The measure is capable to detect network's critical elements.

  20. Emergence of robustness in networks of networks

    Science.gov (United States)

    Roth, Kevin; Morone, Flaviano; Min, Byungjoon; Makse, Hernán A.

    2017-06-01

    A model of interdependent networks of networks (NONs) was introduced recently [Proc. Natl. Acad. Sci. (USA) 114, 3849 (2017), 10.1073/pnas.1620808114] in the context of brain activation to identify the neural collective influencers in the brain NON. Here we investigate the emergence of robustness in such a model, and we develop an approach to derive an exact expression for the random percolation transition in Erdös-Rényi NONs of this kind. Analytical calculations are in agreement with numerical simulations, and highlight the robustness of the NON against random node failures, which thus presents a new robust universality class of NONs. The key aspect of this robust NON model is that a node can be activated even if it does not belong to the giant mutually connected component, thus allowing the NON to be built from below the percolation threshold, which is not possible in previous models of interdependent networks. Interestingly, the phase diagram of the model unveils particular patterns of interconnectivity for which the NON is most vulnerable, thereby marking the boundary above which the robustness of the system improves with increasing dependency connections.

  1. Robustness analysis of chiller sequencing control

    International Nuclear Information System (INIS)

    Liao, Yundan; Sun, Yongjun; Huang, Gongsheng

    2015-01-01

    Highlights: • Uncertainties with chiller sequencing control were systematically quantified. • Robustness of chiller sequencing control was systematically analyzed. • Different sequencing control strategies were sensitive to different uncertainties. • A numerical method was developed for easy selection of chiller sequencing control. - Abstract: Multiple-chiller plant is commonly employed in the heating, ventilating and air-conditioning system to increase operational feasibility and energy-efficiency under part load condition. In a multiple-chiller plant, chiller sequencing control plays a key role in achieving overall energy efficiency while not sacrifices the cooling sufficiency for indoor thermal comfort. Various sequencing control strategies have been developed and implemented in practice. Based on the observation that (i) uncertainty, which cannot be avoided in chiller sequencing control, has a significant impact on the control performance and may cause the control fail to achieve the expected control and/or energy performance; and (ii) in current literature few studies have systematically addressed this issue, this paper therefore presents a study on robustness analysis of chiller sequencing control in order to understand the robustness of various chiller sequencing control strategies under different types of uncertainty. Based on the robustness analysis, a simple and applicable method is developed to select the most robust control strategy for a given chiller plant in the presence of uncertainties, which will be verified using case studies

  2. Primal and dual approaches to adjustable robust optimization

    NARCIS (Netherlands)

    de Ruiter, Frans

    2018-01-01

    Robust optimization has become an important paradigm to deal with optimization under uncertainty. Adjustable robust optimization is an extension that deals with multistage problems. This thesis starts with a short but comprehensive introduction to adjustable robust optimization. Then the two

  3. Effects of Adequate Iodine Supply on the Incidence of Iodine-Induced Thyroid Disorders in Slovenia.

    Science.gov (United States)

    Bajuk, Vid; Zaletel, Katja; Pirnat, Edvard; Hojker, Sergej; Gaberšček, Simona

    2017-04-01

    This study aimed to establish the changes in the incidence and characteristics of iodine-induced hyperthyroidism (II-Hyper) and iodine-induced hypothyroidism (II-Hypo) in the two-year period before and the 10-year period after the increase in mandatory salt iodization from the previous 10 mg/kg of potassium iodide to 25 mg/kg in 1999. Furthermore, the aim was to determine the duration of treatment in II-Hyper patients, since no data regarding severity and treatment of II-Hyper with respect to iodine supply are available. This retrospective study reviewed medical records of 885 Slovenian patients first diagnosed with II-Hyper or II-Hypo between 1998 and 2009 at the Thyroid Department of the University Medical Centre Ljubljana. II-Hyper and II-Hypo were diagnosed by one out of 10 senior internal medicine specialists. The diagnosis was based on an adequate patient history, and laboratory measurements of thyrotropin, thyroid hormones, and thyroid antibodies. In most cases, thyroid ultrasound and thyroid scintigraphy were performed. Demographic characteristics and the type and the duration of treatment were also reviewed. The incidence of II-Hypo was significantly higher after the increase in iodine supply than it was before (p hyperthyroidism decreased, predominantly due to the increased proportion of patients with subclinical hyperthyroidism (p = 0.007 and p = 0.015, respectively). The duration of treatment with antithyroid drugs and perchlorate was significantly shorter after the increase in iodine supply than it was before (p = 0.001 and p = 0.002, respectively). A significantly positive correlation between the year of the occurrence of excessive iodine intake (EII)-induced thyroid disease and the duration of treatment with amiodarone was found (R = 0.132; p = 0.048), suggesting that the longer the patients had an adequate iodine supply, the longer they could take amiodarone before EII-induced thyroid disorder developed. After the

  4. Does Initial Learning about the Meaning of Fractions Present Similar Challenges for Students with and without Adequate Whole-Number Skill?

    Science.gov (United States)

    Namkung, Jessica M; Fuchs, Lynn S; Koziol, Natalie

    2018-01-01

    The purposes of this study were to (a) explore whether early fractions understanding at 4 th grade is differentially challenging for students with versus without adequate whole-number competence and (b) identify specific whole-number skill associated with difficulty in fractions understanding. Based on initial whole-number competence, 1,108 4 th graders were classified as having (a) adequate whole-number competence ( n = 775), (b) less severe whole-number difficulty ( n = 201), and (c) severe whole-number difficulty ( n = 132). At the end of 4 th grade, they were assessed on fractions understanding and further classified as with versus without difficulty in fractions understanding. Multi-level logistic regression indicated that compared to students with adequate whole-number competence, those with less severe whole-number difficulty were almost 5 times as likely to experience difficulty with fractions understanding whereas those with severe whole-number difficulty were about 32 times as likely to experience difficulty with fractions understanding. Students with severe whole-number difficulty were about 7 times as likely to experience difficulty with fractions understanding compared to those with less severe whole-number difficulty. Among students with adequate whole-number competence, the pretest whole-number skill distinguishing those with versus without difficulty in fractions understanding was basic division facts (i.e., 2-digit dividend ÷ 1-digit divisor) and simple multiplication (i.e., 3-digit × 1-digit without regrouping). The role of whole-number competence in developing initial fractions understanding and implications for instruction are discussed.

  5. Early eruption of permanent canines

    Directory of Open Access Journals (Sweden)

    S Madhu

    2012-01-01

    Full Text Available Systemic and local factors can modify the eruption time of teeth. Generalized eruption time changes could be due to some systemic diseases like hyperthyroidism, hypophosphatasia, precocious puberty, Proteus syndrome, etc. Localized early eruption of permanent teeth could be due to early extraction of deciduous teeth. Presented here is an extremely rare case of early eruption of permanent canines in a 7-year old female child. Though the number of such cases is very limited, the clinician should poses adequate knowledge and keeps an open eye to identify such cases.

  6. Robust control systems theory and case studies

    CERN Document Server

    Mackenroth, Uwe

    2004-01-01

    "Robust Control Systems" gives a self-contained introduction to modern Control Theory. It thus adds a textbook to the existing research-oriented literature on Robust Control. The author lays emphasis on the modern aspects of the design of controllers with prescribed performance and robustness properties. Different to the classical engineering approach, a rigorous mathematical treatment is essential for the full understanding and applicability of the modern methods such as H2 or H8 control or methods based on the structured singular value µ. Nevertheless, no prior knowledge of Control Theory is required as the classical fundamentals are introduced within the first few chapters. Subsequently a large part of the text provides elementary examples and industrial case studies, which are developed in full detail to show how modern methods can be applied to advanced problems. They make intensive use of MATLAB, especially the Control Systems Toolbox and the µ-Analysis and Synthesis Toolbox.

  7. Robust Portfolio Optimization using CAPM Approach

    Directory of Open Access Journals (Sweden)

    mohsen gharakhani

    2013-08-01

    Full Text Available In this paper, a new robust model of multi-period portfolio problem has been developed. One of the key concerns in any asset allocation problem is how to cope with uncertainty about future returns. There are some approaches in the literature for this purpose including stochastic programming and robust optimization. Applying these techniques to multi-period portfolio problem may increase the problem size in a way that the resulting model is intractable. In this paper, a novel approach has been proposed to formulate multi-period portfolio problem as an uncertain linear program assuming that asset return follows the single-index factor model. Robust optimization technique has been also used to solve the problem. In order to evaluate the performance of the proposed model, a numerical example has been applied using simulated data.

  8. Occupant behaviour and robustness of building design

    DEFF Research Database (Denmark)

    Buso, Tiziana; Fabi, Valentina; Andersen, Rune Korsholm

    2015-01-01

    in a dynamic building energy simulation tool (IDA ICE). The analysis was carried out by simulating 15 building envelope designs in different thermal zones of an Office Reference Building in 3 climates: Stockholm, Frankfurt and Athens.In general, robustness towards changes in occupants' behaviour increased...... with increasing thermal mass and with decreasing transparent area of the envelope. The importance of the robustness' evaluation is highlighted in this paper, in order to obtain optimized buildings' designs for more accurate and realistic energy predictions.......Occupant behaviour can cause major discrepancies between the designed and the real total energy use in buildings. A possible solution to reduce the differences between predictions and actual performances is designing robust buildings, i.e. buildings whose performances show little variations...

  9. Clustering Incomplete Spectral Data with Robust Methods

    Science.gov (United States)

    Äyrämö, S.; Pölönen, I.; Eskelinen, M. A.

    2017-10-01

    Missing value imputation is a common approach for preprocessing incomplete data sets. In case of data clustering, imputation methods may cause unexpected bias because they may change the underlying structure of the data. In order to avoid prior imputation of missing values the computational operations must be projected on the available data values. In this paper, we apply a robust nan-K-spatmed algorithm to the clustering problem on hyperspectral image data. Robust statistics, such as multivariate medians, are more insensitive to outliers than classical statistics relying on the Gaussian assumptions. They are, however, computationally more intractable due to the lack of closed-form solutions. We will compare robust clustering methods on the bands incomplete data cubes to standard K-means with full data cubes.

  10. Robust Object Tracking Using Valid Fragments Selection.

    Science.gov (United States)

    Zheng, Jin; Li, Bo; Tian, Peng; Luo, Gang

    Local features are widely used in visual tracking to improve robustness in cases of partial occlusion, deformation and rotation. This paper proposes a local fragment-based object tracking algorithm. Unlike many existing fragment-based algorithms that allocate the weights to each fragment, this method firstly defines discrimination and uniqueness for local fragment, and builds an automatic pre-selection of useful fragments for tracking. Then, a Harris-SIFT filter is used to choose the current valid fragments, excluding occluded or highly deformed fragments. Based on those valid fragments, fragment-based color histogram provides a structured and effective description for the object. Finally, the object is tracked using a valid fragment template combining the displacement constraint and similarity of each valid fragment. The object template is updated by fusing feature similarity and valid fragments, which is scale-adaptive and robust to partial occlusion. The experimental results show that the proposed algorithm is accurate and robust in challenging scenarios.

  11. Blebbishields and mitotic cells exhibit robust macropinocytosis.

    Science.gov (United States)

    Jinesh, Goodwin G; Kamat, Ashish M

    2017-03-01

    Cancer stem cells can survive and undergo transformation after apoptosis by initiating robust endocytosis. Endocytosis in-turn drives formation of serpentine filopodia, which promote construction of blebbishields from apoptotic bodies. However, the status and role of macropinocytosis in blebbishields is not known. Here, we show by scanning electron microscopy and by macropinocytosis assays that blebbishields exhibit robust macropinocytosis. Inhibiting dynamin-mediated endocytosis does not affect macropinocytosis in blebbishields or in mitotic cells. In addition, inhibiting macropinocytosis did not inhibit construction of blebbishields from apoptotic bodies. Thus, although apoptotic cancer stem cells exhibit robust macropinocytosis, macropinocytosis is not essential to generate blebbishields, although it may play other roles in blebbishield biology. © 2016 BioFactors, 43(2):181-186, 2017. © 2016 International Union of Biochemistry and Molecular Biology.

  12. Robust optimization in electromagnetic scattering problems

    Science.gov (United States)

    Bertsimas, Dimitris; Nohadani, Omid; Teo, Kwong Meng

    2007-04-01

    In engineering design, the physical properties of a system can often only be described by numerical simulation. Optimization of such systems is usually accomplished heuristically without taking into account that there are implementation errors that lead to very suboptimal, and often, infeasible solutions. We present a robust optimization method for electromagnetic scattering problems with large degrees of freedom and report on results when this technique is applied to optimization of aperiodic dielectric structures. The spatial configuration of 50 dielectric scattering cylinders is optimized to match a desired target function such that the optimal arrangement is robust against placement and prototype errors. Our optimization method inherently improves the robustness of the optimized solution with respect to relevant errors and is suitable for real-world design of materials with unconventional electromagnetic functionalities, as relevant to nanophotonics.

  13. Robust Optimization of Aperiodic Photonic Structures

    Science.gov (United States)

    Nohadani, Omid; Meng Teo, Kwong; Bertsimas, Dimitris

    2007-03-01

    In engineering design, the physical properties of a system can often only be described by numerical simulation. Optimization of such systems is usually accomplished heuristically without taking into account that there are implementation errors that lead to very suboptimal, and often, infeasible solutions. We present a novel robust optimization method for electromagnetic scattering problems with large degrees of freedom, and report on results when this technique is applied to optimization of aperiodic dielectric structures. The spatial configuration of 50 dielectric scattering cylinders is optimized to match a desired target function such that the optimal arrangement is robust against placement and prototype errors. Our optimization method inherently improves the robustness of the optimized solution with respect to relevant errors and is suitable for real-world design of materials with novel electromagnetic functionalities.

  14. Robust fuzzy logic stabilization with disturbance elimination.

    Science.gov (United States)

    Danapalasingam, Kumeresan A

    2014-01-01

    A robust fuzzy logic controller is proposed for stabilization and disturbance rejection in nonlinear control systems of a particular type. The dynamic feedback controller is designed as a combination of a control law that compensates for nonlinear terms in a control system and a dynamic fuzzy logic controller that addresses unknown model uncertainties and an unmeasured disturbance. Since it is challenging to derive a highly accurate mathematical model, the proposed controller requires only nominal functions of a control system. In this paper, a mathematical derivation is carried out to prove that the controller is able to achieve asymptotic stability by processing state measurements. Robustness here refers to the ability of the controller to asymptotically steer the state vector towards the origin in the presence of model uncertainties and a disturbance input. Simulation results of the robust fuzzy logic controller application in a magnetic levitation system demonstrate the feasibility of the control design.

  15. Robust estimation procedure in panel data model

    Energy Technology Data Exchange (ETDEWEB)

    Shariff, Nurul Sima Mohamad [Faculty of Science of Technology, Universiti Sains Islam Malaysia (USIM), 71800, Nilai, Negeri Sembilan (Malaysia); Hamzah, Nor Aishah [Institute of Mathematical Sciences, Universiti Malaya, 50630, Kuala Lumpur (Malaysia)

    2014-06-19

    The panel data modeling has received a great attention in econometric research recently. This is due to the availability of data sources and the interest to study cross sections of individuals observed over time. However, the problems may arise in modeling the panel in the presence of cross sectional dependence and outliers. Even though there are few methods that take into consideration the presence of cross sectional dependence in the panel, the methods may provide inconsistent parameter estimates and inferences when outliers occur in the panel. As such, an alternative method that is robust to outliers and cross sectional dependence is introduced in this paper. The properties and construction of the confidence interval for the parameter estimates are also considered in this paper. The robustness of the procedure is investigated and comparisons are made to the existing method via simulation studies. Our results have shown that robust approach is able to produce an accurate and reliable parameter estimates under the condition considered.

  16. Robust Mediation Analysis Based on Median Regression

    Science.gov (United States)

    Yuan, Ying; MacKinnon, David P.

    2014-01-01

    Mediation analysis has many applications in psychology and the social sciences. The most prevalent methods typically assume that the error distribution is normal and homoscedastic. However, this assumption may rarely be met in practice, which can affect the validity of the mediation analysis. To address this problem, we propose robust mediation analysis based on median regression. Our approach is robust to various departures from the assumption of homoscedasticity and normality, including heavy-tailed, skewed, contaminated, and heteroscedastic distributions. Simulation studies show that under these circumstances, the proposed method is more efficient and powerful than standard mediation analysis. We further extend the proposed robust method to multilevel mediation analysis, and demonstrate through simulation studies that the new approach outperforms the standard multilevel mediation analysis. We illustrate the proposed method using data from a program designed to increase reemployment and enhance mental health of job seekers. PMID:24079925

  17. Handling Occlusions for Robust Augmented Reality Systems

    Directory of Open Access Journals (Sweden)

    Maidi Madjid

    2010-01-01

    Full Text Available Abstract In Augmented Reality applications, the human perception is enhanced with computer-generated graphics. These graphics must be exactly registered to real objects in the scene and this requires an effective Augmented Reality system to track the user's viewpoint. In this paper, a robust tracking algorithm based on coded fiducials is presented. Square targets are identified and pose parameters are computed using a hybrid approach based on a direct method combined with the Kalman filter. An important factor for providing a robust Augmented Reality system is the correct handling of targets occlusions by real scene elements. To overcome tracking failure due to occlusions, we extend our method using an optical flow approach to track visible points and maintain virtual graphics overlaying when targets are not identified. Our proposed real-time algorithm is tested with different camera viewpoints under various image conditions and shows to be accurate and robust.

  18. Robust C-Loss Kernel Classifiers.

    Science.gov (United States)

    Xu, Guibiao; Hu, Bao-Gang; Principe, Jose C

    2018-03-01

    The correntropy-induced loss (C-loss) function has the nice property of being robust to outliers. In this paper, we study the C-loss kernel classifier with the Tikhonov regularization term, which is used to avoid overfitting. After using the half-quadratic optimization algorithm, which converges much faster than the gradient optimization algorithm, we find out that the resulting C-loss kernel classifier is equivalent to an iterative weighted least square support vector machine (LS-SVM). This relationship helps explain the robustness of iterative weighted LS-SVM from the correntropy and density estimation perspectives. On the large-scale data sets which have low-rank Gram matrices, we suggest to use incomplete Cholesky decomposition to speed up the training process. Moreover, we use the representer theorem to improve the sparseness of the resulting C-loss kernel classifier. Experimental results confirm that our methods are more robust to outliers than the existing common classifiers.

  19. Use of Linear Programming to Develop Cost-Minimized Nutritionally Adequate Health Promoting Food Baskets

    DEFF Research Database (Denmark)

    Parlesak, A.; Tetens, Inge; Dejgård Jensen, Jørgen

    2016-01-01

    programming. The FBs were defined using five different constraints: cultural acceptability (CA), or dietary guidelines (DG), or nutrient recommendations (N), or cultural acceptability and nutrient recommendations (CAN), or dietary guidelines and nutrient recommendations (DGN). The variety and number of foods......Food-Based Dietary Guidelines (FBDGs) are developed to promote healthier eating patterns, but increasing food prices may make healthy eating less affordable. The aim of this study was to design a range of cost-minimized nutritionally adequate health-promoting food baskets (FBs) that help prevent...... both micronutrient inadequacy and diet-related non-communicable diseases at lowest cost. Average prices for 312 foods were collected within the Greater Copenhagen area. The cost and nutrient content of five different cost-minimized FBs for a family of four were calculated per day using linear...

  20. Use of Linear Programming to Develop Cost-Minimized Nutritionally Adequate Health Promoting Food Baskets

    DEFF Research Database (Denmark)

    Parlesak, A.; Tetens, Inge; Dejgård Jensen, Jørgen

    2016-01-01

    Food-Based Dietary Guidelines (FBDGs) are developed to promote healthier eating patterns, but increasing food prices may make healthy eating less affordable. The aim of this study was to design a range of cost-minimized nutritionally adequate health-promoting food baskets (FBs) that help prevent...... both micronutrient inadequacy and diet-related non-communicable diseases at lowest cost. Average prices for 312 foods were collected within the Greater Copenhagen area. The cost and nutrient content of five different cost-minimized FBs for a family of four were calculated per day using linear...... programming. The FBs were defined using five different constraints: cultural acceptability (CA), or dietary guidelines (DG), or nutrient recommendations (N), or cultural acceptability and nutrient recommendations (CAN), or dietary guidelines and nutrient recommendations (DGN). The variety and number of foods...

  1. The classification of explosion-proof protected induction motor into adequate temperature and efficiency class

    Science.gov (United States)

    Brinovar, Iztok; Srpčič, Gregor; Seme, Sebastijan; Štumberger, Bojan; Hadžiselimović, Miralem

    2017-07-01

    This article deals with the classification of explosion-proof protected induction motors, which are used in hazardous areas, into adequate temperature and efficiency class. Hazardous areas are defined as locations with a potentially explosive atmosphere where explosion may occur due to present of flammable gasses, liquids or combustible dusts (industrial plants, mines, etc.). Electric motors and electrical equipment used in such locations must be specially designed and tested to prevent electrical initiation of explosion due to high surface temperature and arcing contacts. This article presents the basic tests of three-phase explosion-proof protected induction motor with special emphasis on the measuring system and temperature rise test. All the measurements were performed with high-accuracy instrumentation and accessory equipment and carried out at the Institute of energy technology in the Electric machines and drives laboratory and Applied electrical engineering laboratory.

  2. Are individual transferable quotas an adequate solution to overfishing and overcapacity?

    DEFF Research Database (Denmark)

    Merayo, Eugenia; Nielsen, Rasmus; Hoff, Ayoe

    2018-01-01

    Individual Transferable Quotas stand in large parts of the fisheries economic literature as the panacea that solves all problems of overfishing and overcapacity of world´s fisheries. However, they are also criticized by a number of authors based on their negative social effects. Individual...... Transferable Quotas have been increasingly used during the past decades and are the main management system in a number of countries today. This paper provides evidence of the economic, social and environmental effects of one such system ten years after its introduction in Danish fisheries starting in 2003...... in local fishing communities compared to the national average was found. The Danish experience proves that Individual Transferable Quotas can be an adequate solution with regards to overfishing and overcapacity with also positive effects on the environment due to reduced fuel consumption and fishing...

  3. Overcome of Carbon Catabolite Repression of Bioinsecticides Production by Sporeless Bacillus thuringiensis through Adequate Fermentation Technology

    Directory of Open Access Journals (Sweden)

    Saoussen Ben Khedher

    2014-01-01

    Full Text Available The overcoming of catabolite repression, in bioinsecticides production by sporeless Bacillus thuringiensis strain S22 was investigated into fully controlled 3 L fermenter, using glucose based medium. When applying adequate oxygen profile throughout the fermentation period (75% oxygen saturation, it was possible to partially overcome the catabolite repression, normally occurring at high initial glucose concentrations (30 and 40 g/L glucose. Moreover, toxin production yield by sporeless strain S22 was markedly improved by the adoption of the fed-batch intermittent cultures technology. With 22.5 g/L glucose used into culture medium, toxin production was improved by about 36% when applying fed-batch culture compared to one batch. Consequently, the proposed fed-batch strategy was efficient for the overcome of the carbon catabolite repression. So, it was possible to overproduce insecticidal crystal proteins into highly concentrated medium.

  4. Precise femtosecond laser ablation of dental hard tissue: preliminary investigation on adequate laser parameters

    International Nuclear Information System (INIS)

    Hikov, Todor; Pecheva, Emilia; Petrov, Todor; Montgomery, Paul; Antoni, Frederic; Leong-Hoi, Audrey

    2017-01-01

    This work aims at evaluating the possibility of introducing state-of-the-art commercial femtosecond laser system in restorative dentistry by maintaining well-known benefits of lasers for caries removal, but also in overcoming disadvantages such as thermal damage of irradiated substrate. Femtosecond ablation of dental hard tissue is investigated by changing the irradiation parameters (pulsed laser energy, scanning speed and pulse repetition rate), assessed for enamel and dentin. The femtosecond laser system used in this work may be suitable for cavity preparation in dentin and enamel, due to the expected effective ablation and low temperature increase when using ultra short laser pulses. If adequate laser parameters are selected, this system seems to be promising for promoting a laser-assisted, minimally invasive approach in restorative dentistry. (paper)

  5. Nebulized antibiotics. An adequate option for treating ventilator-associated respiratory infection?

    Science.gov (United States)

    Rodríguez, A; Barcenilla, F

    2015-03-01

    Ventilator-associated tracheobronchitis (VAT) is a frequent complication in critical patients. The 90% of those who develop it receive broad-spectrum antibiotic (ATB) treatment, without any strong evidence of its favorable impact. The use of nebulized ATB could be a valid treatment option, to reduce the use of systemic ATB and the pressure of selection on the local flora. Several studies suggest that an adequate nebulization technique can ensure high levels of ATB even in areas of lung consolidation, and to obtain clinical and microbiological cure. New studies are needed to properly assess the impact of treatment with nebulized ATB on the emergence of resistance. Copyright © 2014 Elsevier España, S.L.U. y SEMICYUC. All rights reserved.

  6. Precise femtosecond laser ablation of dental hard tissue: preliminary investigation on adequate laser parameters

    Science.gov (United States)

    Hikov, Todor; Pecheva, Emilia; Montgomery, Paul; Antoni, Frederic; Leong-Hoi, Audrey; Petrov, Todor

    2017-01-01

    This work aims at evaluating the possibility of introducing state-of-the-art commercial femtosecond laser system in restorative dentistry by maintaining well-known benefits of lasers for caries removal, but also in overcoming disadvantages such as thermal damage of irradiated substrate. Femtosecond ablation of dental hard tissue is investigated by changing the irradiation parameters (pulsed laser energy, scanning speed and pulse repetition rate), assessed for enamel and dentin. The femtosecond laser system used in this work may be suitable for cavity preparation in dentin and enamel, due to the expected effective ablation and low temperature increase when using ultra short laser pulses. If adequate laser parameters are selected, this system seems to be promising for promoting a laser-assisted, minimally invasive approach in restorative dentistry.

  7. Evidenced-based, practical food portion sizes for preschool children and how they fit into a well balanced, nutritionally adequate diet.

    Science.gov (United States)

    More, J A; Emmett, P M

    2015-04-01

    Healthy eating guidelines for 1-4-year-old children are available but evidence-based portion sizes have not been specified. Parents and early-years providers are concerned about under- or over-feeding young children. The present study aimed to report detailed information about appropriate average portion size ranges and suggest a practical food plan for feeding preschool children, providing adequate nutrient intakes within energy requirements. Two sources of information were used to obtain an appropriate portion size range for the types of foods normally eaten by this age group. Median portions of a variety of foods were combined into a food plan fulfilling healthy eating guidelines regarding the number of servings from each food group. The nutrient and energy content of the plan was assessed and compared with recommended adequate nutrient intakes and percentage energy contributions from macronutrients. UK children, aged 1-4 years, taking part in Avon Longitudinal Study of Parents and Children and National Diet and Nutrition Survey, were used in the present study. Portion size ranges were developed for 164 foods. The theoretical food plan using foods with high to medium nutrient density was shown to provide an adequate intake of all nutrients, except vitamin D, for which there are very few food sources. These practical food portion size ranges could be used both in early years settings and in advice to parents. The food plan emphasises the need to include a variety of nutrient-dense foods if a balanced diet is to be achieved for preschool children. © 2014 The British Dietetic Association Ltd.

  8. Use of Linear Programming to Develop Cost-Minimized Nutritionally Adequate Health Promoting Food Baskets.

    Directory of Open Access Journals (Sweden)

    Alexandr Parlesak

    Full Text Available Food-Based Dietary Guidelines (FBDGs are developed to promote healthier eating patterns, but increasing food prices may make healthy eating less affordable. The aim of this study was to design a range of cost-minimized nutritionally adequate health-promoting food baskets (FBs that help prevent both micronutrient inadequacy and diet-related non-communicable diseases at lowest cost.Average prices for 312 foods were collected within the Greater Copenhagen area. The cost and nutrient content of five different cost-minimized FBs for a family of four were calculated per day using linear programming. The FBs were defined using five different constraints: cultural acceptability (CA, or dietary guidelines (DG, or nutrient recommendations (N, or cultural acceptability and nutrient recommendations (CAN, or dietary guidelines and nutrient recommendations (DGN. The variety and number of foods in each of the resulting five baskets was increased through limiting the relative share of individual foods.The one-day version of N contained only 12 foods at the minimum cost of DKK 27 (€ 3.6. The CA, DG, and DGN were about twice of this and the CAN cost ~DKK 81 (€ 10.8. The baskets with the greater variety of foods contained from 70 (CAN to 134 (DGN foods and cost between DKK 60 (€ 8.1, N and DKK 125 (€ 16.8, DGN. Ensuring that the food baskets cover both dietary guidelines and nutrient recommendations doubled the cost while cultural acceptability (CAN tripled it.Use of linear programming facilitates the generation of low-cost food baskets that are nutritionally adequate, health promoting, and culturally acceptable.

  9. Use of Linear Programming to Develop Cost-Minimized Nutritionally Adequate Health Promoting Food Baskets.

    Science.gov (United States)

    Parlesak, Alexandr; Tetens, Inge; Dejgård Jensen, Jørgen; Smed, Sinne; Gabrijelčič Blenkuš, Mojca; Rayner, Mike; Darmon, Nicole; Robertson, Aileen

    2016-01-01

    Food-Based Dietary Guidelines (FBDGs) are developed to promote healthier eating patterns, but increasing food prices may make healthy eating less affordable. The aim of this study was to design a range of cost-minimized nutritionally adequate health-promoting food baskets (FBs) that help prevent both micronutrient inadequacy and diet-related non-communicable diseases at lowest cost. Average prices for 312 foods were collected within the Greater Copenhagen area. The cost and nutrient content of five different cost-minimized FBs for a family of four were calculated per day using linear programming. The FBs were defined using five different constraints: cultural acceptability (CA), or dietary guidelines (DG), or nutrient recommendations (N), or cultural acceptability and nutrient recommendations (CAN), or dietary guidelines and nutrient recommendations (DGN). The variety and number of foods in each of the resulting five baskets was increased through limiting the relative share of individual foods. The one-day version of N contained only 12 foods at the minimum cost of DKK 27 (€ 3.6). The CA, DG, and DGN were about twice of this and the CAN cost ~DKK 81 (€ 10.8). The baskets with the greater variety of foods contained from 70 (CAN) to 134 (DGN) foods and cost between DKK 60 (€ 8.1, N) and DKK 125 (€ 16.8, DGN). Ensuring that the food baskets cover both dietary guidelines and nutrient recommendations doubled the cost while cultural acceptability (CAN) tripled it. Use of linear programming facilitates the generation of low-cost food baskets that are nutritionally adequate, health promoting, and culturally acceptable.

  10. Are oral and maxillofacial surgery residents being adequately trained to care for pediatric patients?

    Science.gov (United States)

    Abramowicz, Shelly; Kaban, Leonard B; Wurtzel, Andrew S; Roser, Steven M

    2017-09-01

    To evaluate whether current oral and maxillofacial surgery (OMS) residents are receiving adequate training and experience to perform specific surgical procedures and anesthesia for pediatric patients. A 17-question survey was sent electronically to fellows of the American Academy of Craniomaxillofacial Surgeons. Descriptive data for individual surgeons, their associated residency programs, and the quantity of specific pediatric procedures they performed were collected. Resident case load for inpatient and outpatient procedures and overall experience in medical, surgical, and anesthetic management of pediatric OMS patients were explored. Surveys were sent to 110 active fellows; 64 completed the questionnaire (58%). There were 59 male fellows and 5 female fellows, with a mean age of 50.4 years. Of those, 68.8% practice in an academic setting. Specifically, 93.8% take after-hours emergency calls covering adult and pediatric patients and 98.4% have admitting privileges at a children's hospital or a pediatric unit in an adult hospital. Their affiliated residency programs include required rotations in pediatrics or pediatric subspecialties. In their opinion, >90% of graduating OMS residents have the appropriate skill set to perform dentoalveolar procedures, outpatient anesthesia, orthognathic procedures, and alveolar bone grafts. However, residents have limited ability to reconstruct pediatric ramus-condyle unit with a costochondral graft. Results of this study indicate that, in the opinion of the respondents, graduates of OMS residency programs have adequate training to perform dentoalveolar procedures, outpatient anesthesia, orthognathic surgery, and alveolar bone grafts in pediatric procedures, but have limited experience with reconstruction of pediatric ramus-condyle unit via costochondral graft. Copyright © 2017 Elsevier Inc. All rights reserved.

  11. Are general surgery residents adequately prepared for hepatopancreatobiliary fellowships? A questionnaire-based study

    Science.gov (United States)

    Osman, Houssam; Parikh, Janak; Patel, Shirali; Jeyarajah, D Rohan

    2015-01-01

    Background The present study was conducted to assess the preparedness of hepatopancreatobiliary (HPB) fellows upon entering fellowship, identify challenges encountered by HPB fellows during the initial part of their HPB training, and identify potential solutions to these challenges that can be applied during residency training. Methods A questionnaire was distributed to all HPB fellows in accredited HPB fellowship programmes in two consecutive academic years (n = 42). Reponses were then analysed. Results A total of 19 (45%) fellows responded. Prior to their fellowship, 10 (53%) were in surgical residency and the rest were in other surgical fellowships or surgical practice. Thirteen (68%) were graduates of university-based residency programmes. All fellows felt comfortable in performing basic laparoscopic procedures independently at the completion of residency and less comfortable in performing advanced laparoscopy. Eight (42%) fellows cited a combination of inadequate case volume and lack of autonomy during residency as the reasons for this lack of comfort. Thirteen (68%) identified inadequate preoperative workup and management as their biggest fear upon entering practice after general surgery training. A total of 17 (89%) fellows felt they were adequately prepared to enter HPB fellowship. Extra rotations in transplant, vascular or minimally invasive surgery were believed to be most helpful in preparing general surgery residents pursing HPB fellowships. Conclusions Overall, HPB fellows felt themselves to be adequately prepared for fellowship. Advanced laparoscopic procedures and the perioperative management of complex patients are two of the challenges facing HPB fellows. General surgery residents who plan to pursue an HPB fellowship may benefit from spending extra rotations on certain subspecialties. Focus on perioperative workup and management should be an integral part of residency and fellowship training. PMID:25387852

  12. When one is not enough: prevalence and characteristics of homes not adequately protected by smoke alarms.

    Science.gov (United States)

    Peek-Asa, C; Allareddy, V; Yang, J; Taylor, C; Lundell, J; Zwerling, C

    2005-12-01

    The National Fire Protection Association (NFPA) has specific recommendations about the number, location, and type of smoke alarms that are needed to provide maximum protection for a household. No previous studies have examined whether or not homes are completely protected according to these guidelines. The authors describe the prevalence and home characteristics associated with compliance to recommendations for smoke alarm installation by the NFPA. Data are from the baseline on-site survey of a randomized trial to measure smoke alarm effectiveness. The trial was housed in a longitudinal cohort study in a rural Iowa county. Of 1005 homes invited, 691 (68.8%) participated. Information about smoke alarm type, placement, and function, as well as home and occupant characteristics, was collected through an on-site household survey. Although 86.0% of homes had at least one smoke alarm, only 22.3% of homes (approximately one in five) were adequately protected according to NFPA guidelines. Fourteen percent of homes had no functioning smoke alarms. More than half of the homes with smoke alarms did not have enough of them or had installed them incorrectly, and 42.4% of homes with alarms had at least one alarm that did not operate. Homes with at least one high school graduate were nearly four times more likely to be fully protected. Homes that had multiple levels, a basement, or were cluttered or poorly cleaned were significantly less likely to be fully protected. These findings indicate that consumers may not be knowledgeable about the number of alarms they need or how to properly install them. Occupants are also not adequately maintaining the alarms that are installed.

  13. Robustness of Distance-to-Default

    DEFF Research Database (Denmark)

    Jessen, Cathrine; Lando, David

    2013-01-01

    . A notable exception is a model with stochastic volatility of assets. In this case both the ranking of firms and the estimated default probabilities using distance-to-default perform significantly worse. We therefore propose a volatility adjustment of the distance-to-default measure, that significantly...... simulations to investigate the robustness of the distance-to-default measure to different model specifications. Overall we find distance-to-default to be robust to a number of deviations from the simple Merton model that involve different asset value dynamics and different default triggering mechanisms...

  14. Design of Robust Neural Network Classifiers

    DEFF Research Database (Denmark)

    Larsen, Jan; Andersen, Lars Nonboe; Hintz-Madsen, Mads

    1998-01-01

    This paper addresses a new framework for designing robust neural network classifiers. The network is optimized using the maximum a posteriori technique, i.e., the cost function is the sum of the log-likelihood and a regularization term (prior). In order to perform robust classification, we present...... a modified likelihood function which incorporates the potential risk of outliers in the data. This leads to the introduction of a new parameter, the outlier probability. Designing the neural classifier involves optimization of network weights as well as outlier probability and regularization parameters. We...

  15. Robust Inference with Multi-way Clustering

    OpenAIRE

    A. Colin Cameron; Jonah B. Gelbach; Douglas L. Miller; Doug Miller

    2009-01-01

    In this paper we propose a variance estimator for the OLS estimator as well as for nonlinear estimators such as logit, probit and GMM. This variance estimator enables cluster-robust inference when there is two-way or multi-way clustering that is non-nested. The variance estimator extends the standard cluster-robust variance estimator or sandwich estimator for one-way clustering (e.g. Liang and Zeger (1986), Arellano (1987)) and relies on similar relatively weak distributional assumptions. Our...

  16. Robustness and modular structure in networks

    DEFF Research Database (Denmark)

    Bagrow, James P.; Lehmann, Sune; Ahn, Yong-Yeol

    2015-01-01

    -12]. Many complex systems, from power grids and the Internet to the brain and society [13-15], can be modeled using modular networks comprised of small, densely connected groups of nodes [16, 17]. These modules often overlap, with network elements belonging to multiple modules [18, 19]. Yet existing work...... on robustness has not considered the role of overlapping, modular structure. Here we study the robustness of these systems to the failure of elements. We show analytically and empirically that it is possible for the modules themselves to become uncoupled or non-overlapping well before the network disintegrates...

  17. Introduction to Robust Estimation and Hypothesis Testing

    CERN Document Server

    Wilcox, Rand R

    2012-01-01

    This revised book provides a thorough explanation of the foundation of robust methods, incorporating the latest updates on R and S-Plus, robust ANOVA (Analysis of Variance) and regression. It guides advanced students and other professionals through the basic strategies used for developing practical solutions to problems, and provides a brief background on the foundations of modern methods, placing the new methods in historical context. Author Rand Wilcox includes chapter exercises and many real-world examples that illustrate how various methods perform in different situations.Introduction to R

  18. Robust median estimator in logisitc regression

    Czech Academy of Sciences Publication Activity Database

    Hobza, T.; Pardo, L.; Vajda, Igor

    2008-01-01

    Roč. 138, č. 12 (2008), s. 3822-3840 ISSN 0378-3758 R&D Projects: GA MŠk 1M0572 Grant - others:Instituto Nacional de Estadistica(ES) MPO FI - IM3/136; GA MŠk(CZ) MTM 2006-06872 Institutional research plan: CEZ:AV0Z10750506 Keywords : Logistic regression * Median * Robustness * Consistency and asymptotic normality * Morgenthaler * Bianco and Yohai * Croux and Hasellbroeck Subject RIV: BB - Applied Statistics, Operational Research Impact factor: 0.679, year: 2008 http://library.utia.cas.cz/separaty/2008/SI/vajda-robust%20median%20estimator%20in%20logistic%20regression.pdf

  19. Robust-mode analysis of hydrodynamic flows

    Science.gov (United States)

    Roy, Sukesh; Gord, James R.; Hua, Jia-Chen; Gunaratne, Gemunu H.

    2017-04-01

    The emergence of techniques to extract high-frequency high-resolution data introduces a new avenue for modal decomposition to assess the underlying dynamics, especially of complex flows. However, this task requires the differentiation of robust, repeatable flow constituents from noise and other irregular features of a flow. Traditional approaches involving low-pass filtering and principle components analysis have shortcomings. The approach outlined here, referred to as robust-mode analysis, is based on Koopman decomposition. Three applications to (a) a counter-rotating cellular flame state, (b) variations in financial markets, and (c) turbulent injector flows are provided.

  20. The Robustness of High Danish National Happiness

    DEFF Research Database (Denmark)

    Hussain, M. Azhar

    2014-01-01

    Denmark’s top position in various rankings of country happiness is well-documented. This study goes beyond the national average comparisons and investigates whether Denmark’s top position is also found when we disaggregate data in line with social categories often used within the social sciences...... of the five rounds are included in this study. The results show that Denmark’s position at the top of the happiness scale is also robust when we look at population subgroups, but not in the sense that Denmark dominates all countries for all years. Instead, a modified version of robustness is necessary...

  1. Return Predictability, Model Uncertainty, and Robust Investment

    DEFF Research Database (Denmark)

    Lukas, Manuel

    Stock return predictability is subject to great uncertainty. In this paper we use the model confidence set approach to quantify uncertainty about expected utility from investment, accounting for potential return predictability. For monthly US data and six representative return prediction models, we...... find that confidence sets are very wide, change significantly with the predictor variables, and frequently include expected utilities for which the investor prefers not to invest. The latter motivates a robust investment strategy maximizing the minimal element of the confidence set. The robust investor...... allocates a much lower share of wealth to stocks compared to a standard investor....

  2. 21 CFR 740.10 - Labeling of cosmetic products for which adequate substantiation of safety has not been obtained.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 7 2010-04-01 2010-04-01 false Labeling of cosmetic products for which adequate..., DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) COSMETICS COSMETIC PRODUCT WARNING STATEMENTS Warning Statements § 740.10 Labeling of cosmetic products for which adequate substantiation of safety has not been...

  3. In Few Words: Linguistic Gap but Adequate Narrative Structure in Preschool Bilingual Children

    Science.gov (United States)

    Bonifacci, Paola; Barbieri, Margherita; Tomassini, Marta; Roch, Maja

    2018-01-01

    The aim of this study was to compare linguistic and narrative skills of monolingual and bilingual preschoolers and to estimate linguistic predictors of the macro-structural level of narratives. A battery of linguistic measures in Italian was administered to sixty-four Monolinguals and sixty-four Early Bilinguals; it included Vocabulary,…

  4. Play is indispensable for an adequate development of coping with social challenges in the rat

    NARCIS (Netherlands)

    Hol, T; Van Ree, JM; Spruijt, BM; Everts, H; Koolhaas, JM

    In this study, young rats were deprived of early social interactions during weeks 4 and 5 of life. Different behavior al tests were conducted in adulthood to study the behavioral responses of rats lacking ear ly social experiences. Juvenile deprivation resulted in decreased social activity and an

  5. A Robust Interpretation of Teaching Evaluation Ratings

    Science.gov (United States)

    Bi, Henry H.

    2018-01-01

    There are no absolute standards regarding what teaching evaluation ratings are satisfactory. It is also problematic to compare teaching evaluation ratings with the average or with a cutoff number to determine whether they are adequate. In this paper, we use average and standard deviation charts (X[overbar]-S charts), which are based on the theory…

  6. Robust fitting of diurnal brightness temperature cycle

    CSIR Research Space (South Africa)

    Udahemuka, G

    2007-11-01

    Full Text Available . In this paper, diurnal brightness temperatures received from the METEOSAT Second Generation (MSG) satellite were interpolated for missing data based on a model, and a performance test was performed by comparing a new approach based on robust modelling...

  7. Robust and Adaptive Control With Aerospace Applications

    CERN Document Server

    Lavretsky, Eugene

    2013-01-01

    Robust and Adaptive Control shows the reader how to produce consistent and accurate controllers that operate in the presence of uncertainties and unforeseen events. Driven by aerospace applications the focus of the book is primarily on continuous-dynamical systems.  The text is a three-part treatment, beginning with robust and optimal linear control methods and moving on to a self-contained presentation of the design and analysis of model reference adaptive control (MRAC) for nonlinear uncertain dynamical systems. Recent extensions and modifications to MRAC design are included, as are guidelines for combining robust optimal and MRAC controllers. Features of the text include: ·         case studies that demonstrate the benefits of robust and adaptive control for piloted, autonomous and experimental aerial platforms; ·         detailed background material for each chapter to motivate theoretical developments; ·         realistic examples and simulation data illustrating key features ...

  8. Robust control charts in statistical process control

    NARCIS (Netherlands)

    Nazir, H.Z.

    2014-01-01

    The presence of outliers and contaminations in the output of the process highly affects the performance of the design structures of commonly used control charts and hence makes them of less practical use. One of the solutions to deal with this problem is to use control charts which are robust

  9. Robust Utility Maximization Under Convex Portfolio Constraints

    International Nuclear Information System (INIS)

    Matoussi, Anis; Mezghani, Hanen; Mnif, Mohamed

    2015-01-01

    We study a robust maximization problem from terminal wealth and consumption under a convex constraints on the portfolio. We state the existence and the uniqueness of the consumption–investment strategy by studying the associated quadratic backward stochastic differential equation. We characterize the optimal control by using the duality method and deriving a dynamic maximum principle

  10. Robust Utility Maximization Under Convex Portfolio Constraints

    Energy Technology Data Exchange (ETDEWEB)

    Matoussi, Anis, E-mail: anis.matoussi@univ-lemans.fr [Université du Maine, Risk and Insurance institut of Le Mans Laboratoire Manceau de Mathématiques (France); Mezghani, Hanen, E-mail: hanen.mezghani@lamsin.rnu.tn; Mnif, Mohamed, E-mail: mohamed.mnif@enit.rnu.tn [University of Tunis El Manar, Laboratoire de Modélisation Mathématique et Numérique dans les Sciences de l’Ingénieur, ENIT (Tunisia)

    2015-04-15

    We study a robust maximization problem from terminal wealth and consumption under a convex constraints on the portfolio. We state the existence and the uniqueness of the consumption–investment strategy by studying the associated quadratic backward stochastic differential equation. We characterize the optimal control by using the duality method and deriving a dynamic maximum principle.

  11. Finite Algorithms for Robust Linear Regression

    DEFF Research Database (Denmark)

    Madsen, Kaj; Nielsen, Hans Bruun

    1990-01-01

    The Huber M-estimator for robust linear regression is analyzed. Newton type methods for solution of the problem are defined and analyzed, and finite convergence is proved. Numerical experiments with a large number of test problems demonstrate efficiency and indicate that this kind of approach may...

  12. Robust topology optimization accounting for geometric imperfections

    DEFF Research Database (Denmark)

    Schevenels, M.; Jansen, M.; Lombaert, Geert

    2013-01-01

    performance. As a consequence, the actual structure may be far from optimal. In this paper, a robust approach to topology optimization is presented, taking into account two types of geometric imperfections: variations of (1) the crosssections and (2) the locations of structural elements. The first type...

  13. Regularized robust coding for face recognition.

    Science.gov (United States)

    Yang, Meng; Zhang, Lei; Yang, Jian; Zhang, David

    2013-05-01

    Recently the sparse representation based classification (SRC) has been proposed for robust face recognition (FR). In SRC, the testing image is coded as a sparse linear combination of the training samples, and the representation fidelity is measured by the l2-norm or l1 -norm of the coding residual. Such a sparse coding model assumes that the coding residual follows Gaussian or Laplacian distribution, which may not be effective enough to describe the coding residual in practical FR systems. Meanwhile, the sparsity constraint on the coding coefficients makes the computational cost of SRC very high. In this paper, we propose a new face coding model, namely regularized robust coding (RRC), which could robustly regress a given signal with regularized regression coefficients. By assuming that the coding residual and the coding coefficient are respectively independent and identically distributed, the RRC seeks for a maximum a posterior solution of the coding problem. An iteratively reweighted regularized robust coding (IR(3)C) algorithm is proposed to solve the RRC model efficiently. Extensive experiments on representative face databases demonstrate that the RRC is much more effective and efficient than state-of-the-art sparse representation based methods in dealing with face occlusion, corruption, lighting, and expression changes, etc.

  14. Robustness of Long Span Reciprocal Timber Structures

    DEFF Research Database (Denmark)

    Balfroid, Nathalie; Kirkegaard, Poul Henning

    2011-01-01

    Robustness of structural systems has obtained a renewed interest due to a much more frequent use of advanced types of structures with limited redundancy and serious consequences in case of failure. The interest has also been facilitated due to recently severe structural failures such as that at R...

  15. Robust classification using mixtures of dependency networks

    DEFF Research Database (Denmark)

    Gámez, José A.; Mateo, Juan L.; Nielsen, Thomas Dyhre

    2008-01-01

    -ups are often obtained at the expense of accuracy. In this paper we try to address this issue through the use of mixtures of dependency networks. To reduce learning time and improve robustness when dealing with data sparse classes, we outline methods for reusing calculations across mixture components. Finally...

  16. Robustness of dynamic systems with parameter uncertainties

    CERN Document Server

    Balemi, S; Truöl, W

    1992-01-01

    Robust Control is one of the fastest growing and promising areas of research today. In many practical systems there exist uncertainties which have to be considered in the analysis and design of control systems. In the last decade methods were developed for dealing with dynamic systems with unstructured uncertainties such as HOO_ and £I-optimal control. For systems with parameter uncertainties, the seminal paper of V. L. Kharitonov has triggered a large amount of very promising research. An international workshop dealing with all aspects of robust control was successfully organized by S. P. Bhattacharyya and L. H. Keel in San Antonio, Texas, USA in March 1991. We organized the second international workshop in this area in Ascona, Switzer­ land in April 1992. However, this second workshop was restricted to robust control of dynamic systems with parameter uncertainties with the objective to concentrate on some aspects of robust control. This book contains a collection of papers presented at the International W...

  17. Robust tensor estimation in diffusion tensor imaging

    Science.gov (United States)

    Maximov, Ivan I.; Grinberg, Farida; Jon Shah, N.

    2011-12-01

    The signal response measured in diffusion tensor imaging is subject to detrimental influences caused by noise. Noise fields arise due to various contributions such as thermal and physiological noise and sources related to the hardware imperfection. As a result, diffusion tensors estimated by different linear and non-linear least squares methods in absence of a proper noise correction tend to be substantially corrupted. In this work, we propose an advanced tensor estimation approach based on the least median squares method of the robust statistics. Both constrained and non-constrained versions of the method are considered. The performance of the developed algorithm is compared to that of the conventional least squares method and of the alternative robust methods proposed in the literature. Two examples of simulated diffusion attenuations and experimental in vivo diffusion data sets were used as a basis for comparison. The robust algorithms were shown to be advantageous compared to the least squares method in the cases where elimination of the outliers is desirable. Additionally, the constraints were applied in order to prevent generation of the non-positive definite tensors and reduce related artefacts in the maps of fractional anisotropy. The developed method can potentially be exploited also by other MR techniques where a robust regression or outlier localisation is required.

  18. Grassmann Averages for Scalable Robust PCA

    DEFF Research Database (Denmark)

    Hauberg, Søren; Feragen, Aasa; Black, Michael J.

    2014-01-01

    to vectors (subspaces) or elements of vectors; we focus on the latter and use a trimmed average. The resulting Trimmed Grassmann Average (TGA) is particularly appropriate for computer vision because it is robust to pixel outliers. The algorithm has low computational complexity and minimal memory requirements...

  19. Robust balance shift control with posture optimization

    NARCIS (Netherlands)

    Kavafoglu, Z.; Kavafoglu, Ersan; Egges, J.

    2015-01-01

    In this paper we present a control framework which creates robust and natural balance shifting behaviours during standing. Given high-level features such as the position of the center of mass projection and the foot configurations, a kinematic posture satisfying these features is synthesized using

  20. Stability and robustness analysis of acyclic timetable

    NARCIS (Netherlands)

    Goverde, R.M.P.; Yan, F.

    2015-01-01

    o satisfy the growing passenger transportation demands and improve the service quality n railway system, a more stable and robust timetable needs to be designed while considering highly utilized capacity. Acyclic timetable is extensively applied in large ailway networks. In order to acquire the

  1. Robust giant magnetoresistive effect type multilayer sensor

    NARCIS (Netherlands)

    Lenssen, K.M.H.; Kuiper, A.E.T.; Roozeboom, F.

    2002-01-01

    A robust Giant Magneto Resistive effect type multilayer sensor comprising a free and a pinned ferromagnetic layer, which can withstand high temperatures and strong magnetic fields as required in automotive applications. The GMR multi-layer has an asymmetric magneto-resistive curve and enables

  2. Robustness of river basin water quality models

    NARCIS (Netherlands)

    de Blois, Chris; Wind, H.G.; de Kok, Jean-Luc; Koppeschaar, K.

    2003-01-01

    In this paper the concept of robustness is introduced and applied to a model for the analysis of the impacts of spatially distributed policy measures on the surface water quality on a river basin scale. In this model the influence of precipitation on emissions and resuspension of pollutants in the

  3. Chromatin regulators, phenotypic robustness and autism risk

    Directory of Open Access Journals (Sweden)

    Reut eSuliman

    2014-04-01

    Full Text Available Though extensively characterized clinically, the causes of autism spectrum disorder (ASD remain a mystery. ASD is known to have a strong genetic basis, but it is genetically very heterogeneous. Recent studies have estimated that de novo disruptive mutations in hundreds of genes may contribute to ASD. However, it is unclear how it is possible for mutations in so many different genes to contribute to ASD. Recent findings suggest that many of the mutations disrupt genes involved in transcription regulation that are expressed prenatally in the developing brain. De novo disruptive mutations are also more frequent in girls with ASD, despite the fact that ASD is more prevalent in boys. In this paper, we hypothesize that loss of robustness may contribute to ASD. Loss of phenotypic robustness may be caused by mutations that disrupt capacitors that operate in the developing brain. This may lead to the release of cryptic genetic variation that contributes to ASD. Reduced robustness is consistent with the observed variability in expressivity and incomplete penetrance. It is also consistent with the hypothesis that the development of the female brain is more robust, and it may explain the higher rate and severity of disruptive de novo mutations in girls with ASD.

  4. Robust Satisfiability of Systems of Equations

    Czech Academy of Sciences Publication Activity Database

    Franek, Peter; Krčál, M.

    2015-01-01

    Roč. 62, č. 4 (2015), Article 26 ISSN 0004-5411 R&D Projects: GA ČR GBP202/12/G061 Grant - others:GA MŠk(CZ) LL1201 Institutional support: RVO:67985807 Keywords : nonlinear equations * satisfability * undecibility * topological extensions * uncertainty * robustness Subject RIV: IN - Informatics, Computer Science Impact factor: 1.803, year: 2015

  5. Neuromorphic Configurable Architecture for Robust Motion Estimation

    Directory of Open Access Journals (Sweden)

    Guillermo Botella

    2008-01-01

    Full Text Available The robustness of the human visual system recovering motion estimation in almost any visual situation is enviable, performing enormous calculation tasks continuously, robustly, efficiently, and effortlessly. There is obviously a great deal we can learn from our own visual system. Currently, there are several optical flow algorithms, although none of them deals efficiently with noise, illumination changes, second-order motion, occlusions, and so on. The main contribution of this work is the efficient implementation of a biologically inspired motion algorithm that borrows nature templates as inspiration in the design of architectures and makes use of a specific model of human visual motion perception: Multichannel Gradient Model (McGM. This novel customizable architecture of a neuromorphic robust optical flow can be constructed with FPGA or ASIC device using properties of the cortical motion pathway, constituting a useful framework for building future complex bioinspired systems running in real time with high computational complexity. This work includes the resource usage and performance data, and the comparison with actual systems. This hardware has many application fields like object recognition, navigation, or tracking in difficult environments due to its bioinspired and robustness properties.

  6. New solutions for NPP robustness improvement

    International Nuclear Information System (INIS)

    Wolski, Alexander

    2013-01-01

    Fukushima accident has triggered a major re-assessment of robustness of nuclear stations. First round of evaluations has been Finished. Improvement areas and strategies have been identified. Implementation of upgrades has started world-wide. New solutions can provide substantial benefits

  7. Robust unit commitment with dispatchable wind power

    NARCIS (Netherlands)

    Morales Espana, G.; Lorca, Álvaro; de Weerdt, M.M.

    The increasing penetration of uncertain generation such as wind and solar in power systems imposes new challenges to the unit commitment (UC) problem, one of the most critical tasks in power systems operations. The two most common approaches to address these challenges — stochastic and robust

  8. Quantifying the robustness of metro networks

    NARCIS (Netherlands)

    Wang, X.; Koç, Y.; Derrible, S.; Nasir Ahmad, Sk.; Kooij, R.E.

    2015-01-01

    Metros (heavy rail transit systems) are integral parts of urban transportation systems. Failures in their operations can have serious impacts on urban mobility, and measuring their robustness is therefore critical. Moreover, as physical networks, metros can be viewed as network topological entities,

  9. Robustness of Distance-to-Default

    DEFF Research Database (Denmark)

    Jessen, Cathrine; Lando, David

    2013-01-01

    Distance-to-default is a remarkably robust measure for ranking firms according to their risk of default. The ranking seems to work despite the fact that the Merton model from which the measure is derived produces default probabilities that are far too small when applied to real data. We use simul...

  10. Robust Geometric Control of a Distillation Column

    DEFF Research Database (Denmark)

    Kymmel, Mogens; Andersen, Henrik Weisberg

    1987-01-01

    A frequency domain method, which makes it possible to adjust multivariable controllers with respect to both nominal performance and robustness, is presented. The basic idea in the approach is that the designer assigns objectives such as steady-state tracking, maximum resonance peaks, bandwidth, m...... is used to examine and improve geometric control of a binary distillation column....

  11. Structurally robust control of complex networks

    Science.gov (United States)

    Nacher, Jose C.; Akutsu, Tatsuya

    2015-01-01

    Robust control theory has been successfully applied to numerous real-world problems using a small set of devices called controllers. However, the real systems represented by networks contain unreliable components and modern robust control engineering has not addressed the problem of structural changes on complex networks including scale-free topologies. Here, we introduce the concept of structurally robust control of complex networks and provide a concrete example using an algorithmic framework that is widely applied in engineering. The developed analytical tools, computer simulations, and real network analyses lead herein to the discovery that robust control can be achieved in scale-free networks with exactly the same order of controllers required in a standard nonrobust configuration by adjusting only the minimum degree. The presented methodology also addresses the probabilistic failure of links in real systems, such as neural synaptic unreliability in Caenorhabditis elegans, and suggests a new direction to pursue in studies of complex networks in which control theory has a role.

  12. Highly Robust Methods in Data Mining

    Czech Academy of Sciences Publication Activity Database

    Kalina, Jan

    2013-01-01

    Roč. 8, č. 1 (2013), s. 9-24 ISSN 1452-4864 Institutional support: RVO:67985807 Keywords : data mining * robust statistics * high-dimensional data * cluster analysis * logistic regression * neural networks Subject RIV: BB - Applied Statistics, Operational Research

  13. Automatic Synthesis of Robust and Optimal Controllers

    DEFF Research Database (Denmark)

    Cassez, Franck; Jessen, Jan Jacob; Larsen, Kim Guldstrand

    2009-01-01

    In this paper, we show how to apply recent tools for the automatic synthesis of robust and near-optimal controllers for a real industrial case study. We show how to use three different classes of models and their supporting existing tools, Uppaal-TiGA for synthesis, phaver for verification...

  14. A robust adaptive controller for robot manipulators

    NARCIS (Netherlands)

    Berghuis, Harry; Berghuis, Harry; Ortega, Romeo; Nijmeijer, Henk

    1992-01-01

    The authors propose a globally convergent adaptive control scheme for robot motion control with the following features: first, the adaptation law processes enhanced robustness with respect to noisy velocity measurements; secondly, the controller does not require the inclusion of high-gain loops that

  15. Robust weighted scan matching with quadtrees

    NARCIS (Netherlands)

    Visser, A.; Slamet, B.A.; Pfingsthorn, M.

    2009-01-01

    This paper presents the improvement of the robustness and accuracy of the weighted scan matching algorithm matching against the union of earlier acquired scans. The approach allows to reduce the correspondence error, which is explicitly modeled in the weighted scan matching algorithm, by providing a

  16. Robust Pedestrian Navigation for Challenging Applications

    OpenAIRE

    Gilliéron, PY; Renaudin, V

    2009-01-01

    Presentation of a concept for robust indoor navigation. The concept is based on three key elements: - the use of an absolute geographical reference - the hybridisation of complementary technologies - specific motion models. This concept is illustrated by the means of two applications: the urban displacement of blind people and the indoor guidance of fire-fighters

  17. Robust inference in sample selection models

    KAUST Repository

    Zhelonkin, Mikhail

    2015-11-20

    The problem of non-random sample selectivity often occurs in practice in many fields. The classical estimators introduced by Heckman are the backbone of the standard statistical analysis of these models. However, these estimators are very sensitive to small deviations from the distributional assumptions which are often not satisfied in practice. We develop a general framework to study the robustness properties of estimators and tests in sample selection models. We derive the influence function and the change-of-variance function of Heckman\\'s two-stage estimator, and we demonstrate the non-robustness of this estimator and its estimated variance to small deviations from the model assumed. We propose a procedure for robustifying the estimator, prove its asymptotic normality and give its asymptotic variance. Both cases with and without an exclusion restriction are covered. This allows us to construct a simple robust alternative to the sample selection bias test. We illustrate the use of our new methodology in an analysis of ambulatory expenditures and we compare the performance of the classical and robust methods in a Monte Carlo simulation study.

  18. Robust network design for multispecies conservation

    Science.gov (United States)

    Ronan Le Bras; Bistra Dilkina; Yexiang Xue; Carla P. Gomes; Kevin S. McKelvey; Michael K. Schwartz; Claire A. Montgomery

    2013-01-01

    Our work is motivated by an important network design application in computational sustainability concerning wildlife conservation. In the face of human development and climate change, it is important that conservation plans for protecting landscape connectivity exhibit certain level of robustness. While previous work has focused on conservation strategies that result...

  19. Parametric uncertainty modeling for robust control

    DEFF Research Database (Denmark)

    Rasmussen, K.H.; Jørgensen, Sten Bay

    1999-01-01

    to perform robustness analysis on a control system using the structured singular value. The idea behind the proposed method is to fit a rational function to the parameter variation. The parameter variation can then be expressed as a linear fractional transformation (LFT), It is discussed how the proposed....... (C) 1999 Elsevier Science Ltd. All rights reserved....

  20. Robust online face tracking-by-detection

    NARCIS (Netherlands)

    Comaschi, F.; Stuijk, S.; Basten, T.; Corporaal, H.

    2016-01-01

    The problem of online face tracking from unconstrained videos is still unresolved. Challenges range from coping with severe online appearance variations to coping with occlusion. We propose RFTD (Robust Face Tracking-by-Detection), a system which combines tracking and detection into a single

  1. A robust interpretation of duration calculus

    DEFF Research Database (Denmark)

    Franzle, M.; Hansen, Michael Reichhardt

    2005-01-01

    Calculus (DC), our findings are that the robust interpretation of DC is equivalent to a multi-valued interpretation that uses the real numbers as semantic domain and assigns Lipschitz-continuous interpretations to all operators of DC. Furthermore, this continuity permits approximation between discrete...

  2. Some Diagnostic Tools in Robust Econometrics

    Czech Academy of Sciences Publication Activity Database

    Kalina, Jan

    2011-01-01

    Roč. 50, č. 2 (2011), s. 55-67 ISSN 0231-9721 Grant - others:GA ČR(CZ) GA402/09/0557 Institutional research plan: CEZ:AV0Z10300504 Keywords : robust regression * autocorrelated errors * heteroscedastic regression * instrumental variables * least weighted squares Subject RIV: BB - Applied Statistics, Operational Research http://dml.cz/handle/10338.dmlcz/141754

  3. Quantitative Robust Control Engineering: Theory and Applications

    Science.gov (United States)

    2006-09-01

    the twentieth century, there has been a tremendous advance in the state-of-the- art of robust frequency domain methods. One of the main techniques...Templates [28]. Bartlett, A.C., Tesi , A., Vicino, A. (1993). Frequency response of uncertain systems with interval plants. IEEE Trans. On Automatic

  4. Replication and Robustness in Developmental Research

    Science.gov (United States)

    Duncan, Greg J.; Engel, Mimi; Claessens, Amy; Dowsett, Chantelle J.

    2014-01-01

    Replications and robustness checks are key elements of the scientific method and a staple in many disciplines. However, leading journals in developmental psychology rarely include explicit replications of prior research conducted by different investigators, and few require authors to establish in their articles or online appendices that their key…

  5. Robust Refinement as Implemented in TOPAS

    Energy Technology Data Exchange (ETDEWEB)

    Stone, K.; Stephens, P

    2010-01-01

    A robust refinement procedure is implemented in the program TOPAS through an iterative reweighting of the data. Examples are given of the procedure as applied to fitting partially overlapped peaks by full and partial models and also of the structures of ibuprofen and acetaminophen in the presence of unmodeled impurity contributions

  6. Does current cefazolin dosing achieve adequate tissue and blood concentrations in obese women undergoing cesarean section?

    Science.gov (United States)

    Kram, Jessica J F; Greer, Danielle M; Cabrera, Omar; Burlage, Robert; Forgie, Marie M; Siddiqui, Danish S

    2017-03-01

    Prophylactic administration of antibiotics preceding cesarean delivery is the most effective measure taken for preventing postpartum infection. While obese women are at greater risk for infection than non-obese women, evidence-based recommendations for modifying dosing in these women are limited. The purpose of this study was to determine whether obese women undergoing cesarean delivery similarly reach adequate cefazolin concentrations within tissue and blood when weighing tissue (following skin incision and before skin closure), myometrial tissue, fetal cord blood, and maternal blood were collected to assess whether cefazolin concentrations were adequate, i.e., at/above the minimum inhibitory concentration (MIC). Concentrations, based on inhibition zones for Streptococcus sanguinis, were calculated per gram of solid tissue and milliliter of blood. For all sample types, log-transformed concentrations were compared between dosage groups. Using a range of published MICs (1-8μg/mL or μg/g), odds ratios, describing differential odds of falling below the MIC between dosage groups, were also computed. Women who received 2g (n=65) versus 3g (n=19) of cefazolin did not significantly differ by maternal or gestational age, race/ethnicity, pre-operative hemoglobin, estimated blood loss, fluid administration, duration of surgery, or timing of sample collections relative to cefazolin administration (Ps>0.05). Dosage groups also did not differ in cefazolin concentration (median [interquartile range]) within adipose tissue following skin incision (5.30μg/g [3.00-9.60] vs. 6.35μg/g [3.90-8.40]; P=0.551), adipose tissue before skin closure (4.45μg/g [2.78-7.25] vs. 6.90μg/g [2.60-10.6]; P=0.342), myometrial tissue (13.1μg/g [8.60-19.6] vs. 15.7μg/g [10.8-21.7]; P=0.116), or maternal blood (41.6μg/mL [26.3-57.0] vs. 45.3μg/mL [36.7-68.3]; P=0.143). However, cord blood concentrations differed significantly (19.5μg/mL [13.7-28.5] vs. 27.9μg/mL [15.8-39.4]; P=0.032), and

  7. Robust FIR Beamforming Applied TO Medical Ultrasound

    Science.gov (United States)

    Guenther, Drake A.; Walker, William F.

    2009-01-01

    We previously described a beamformer architecture that replaces the single apodization weights on each receive channel with channel-unique finite impulse response (FIR) filters. The filter weights are designed to optimize the contrast resolution performance of the imaging system. While the FIR beamformer offers significant gains in contrast resolution, the beamformer suffers from low sensitivity and its performance rapidly degrades in the presence of noise. In this paper a new method is presented to improve the robustness of the FIR beamformer to electronic noise as well as variation or uncertainty in the array response. A method is also described, which controls the sidelobe levels of the FIR beamformer’s spatial response by applying an arbitrary weighting function in the filter design algorithm. The robust FIR beamformer is analyzed using a generalized cystic resolution metric that quantifies a beamformer’s clinical imaging performance as a function of cyst size and channel input signal-to-noise ratio (SNR). Fundamental performance limits are compared between two robust FIR beamformers (the dynamic focus FIR (DF-FIR) beamformer and the group focus FIR (GF-FIR) beamformer), the conventional delay-and-sum (DAS) beamformer, and the spatial matched filter (SMF) beamformer. Results from this study show that the new DF- and GF-FIR beamformers are more robust to electronic noise compared to the optimal contrast resolution FIR beamformer. Furthermore, the added robustness only comes with a slight loss in cystic resolution. Results from the generalized cystic resolution metric show that a 9-tap robust FIR beamformer outperforms the SMF and DAS beamformer until receive channel input SNR drops below −5 dB; whereas, the 9-tap optimal contrast resolution beamformer’s performance deteriorates around 50 dB SNR. The effects of moderate phase aberrations, characterized by an a priori root-mean-square strength of 28 ns and an a priori full-width at half-maximum correlation

  8. Adequate sleep among adolescents is positively associated with health status and health-related behaviors

    Directory of Open Access Journals (Sweden)

    Jeng Yi-Jong

    2006-03-01

    Full Text Available Abstract Background Amount of sleep is an important indicator of health and well-being in children and adolescents. Adequate sleep (AS: adequate sleep is defined as 6–8 hours per night regularly is a critical factor in adolescent health and health-related behaviors. The present study was based on a health promotion project previously conducted on adolescents in Tao-Yuan County, Taiwan. The aim was to examine the relationship between AS during schooldays and excessive body weight, frequency of visiting doctors and health-related behaviors among Taiwanese adolescents. Methods A cross-sectional study design, categorical and multivariate data analyses were used. The hypotheses investigated were: high frequency of AS is positively associated with lack of obesity and less frequent visits to doctors; and high frequency AS is positively associated with health-related behavior. Results A total of 656 boys (53.2% and girls (46.8%, ranging in age from 13–18 years were studied between January and June 2004. Three hundred and fifty seven subjects (54% reported that they slept less than the suggested 6–8 hours on schooldays. A significant negative association was found between low sleep and of the following health-related behaviors: (1 life appreciation; (2 taking responsibility for health; (3 adopting healthy diet; (4 effective stress management; (5 regular exercise; and (6 total AHP score. High frequency AS was associated with low frequencies of obesity after potential confounding factors were controlled. Junior high school adolescents reported significantly higher frequencies of AS than high school participants. Gender, family structure, home location and frequency of television watching or computer use were not significantly associated with AS. Conclusion These findings support the proposition that AS is associated with good health status and high-frequency adoption of health-related behavior. Furthermore, these findings suggest that inadequate

  9. Can the ASAR Global Monitoring Mode Product Adequately Capture Spatial Soil Moisture Variability?

    Science.gov (United States)

    Mladenova, I.; Lakshmi, V.; Walker, J.; Panciera, R.; Wagner, W.; Doubkova, M.

    2008-12-01

    Global soil moisture (SM) monitoring in the past several decades has been undertaken mainly at coarse spatial resolution, which is not adequate for addressing small-scale phenomena and processes. The currently operational Advanced Microwave Scanning Radiometer (NASA) and future planned missions such as the Soil Moisture and Ocean Salinity (ESA) and the Soil Moisture Active Passive (NASA) will remain resolution limited. Finer scale soil moisture estimates can be achieved either by down-scaling the available coarse resolution radiometer and scatterometer (i.e. ERS1/2, ASCAT) observations or by using high resolution active microwave SAR type systems (typical resolution is in the order of meters). Considering the complex land surface - backscatter signal interaction, soil moisture inversion utilizing active microwave observations is difficult and generally needs supplementary data. Algorithms based on temporal change detection offer an alternative less complex approach for deriving (and disaggregating coarse) soil moisture estimates. Frequent monitoring and low frequency range along with a high pixel resolution are essential preconditions when characterizing spatial and temporal soil moisture variability. An alternative active system that meets these requirements is the Advance Synthetic Aperture Radar (ASAR) on ENVISAT [C-band, global, 1 km in Global Monitoring (GM) Mode]. The Vienna University of Technology (TU Wien) has developed a 1 km soil moisture product using the temporal change detection approach and the ASAR GM. The TU Wien SM product sensitivity was evaluated at two scales: point (using in situ data from permanent soil moisture stations) and regional [using ground measured data and aircraft estimates derived from the Polarimetric L-band Microwave Radiometer (PLMR)] over the National Airborne Field Experiment (NAFE'05) area located in the Goulburn catchment, SE Australia. The month long (November 2005) campaign was undertaken in a region predominantly covered

  10. Experiments of conditioning C-14 immobilized in a solid matrix adequate for final disposal

    International Nuclear Information System (INIS)

    Havris, A.; Havris, C.; Deneanu, N.

    2001-01-01

    The operation of Cernavoda NPP entails production and management of significant amounts of radioactive waste. 80% of the β - γ activity, except for the spent fuel contribution, originates in the ion exchange resin wastes. Long term storage of utilised ion exchangers in shielded pools implies large storing rooms, additional costs for technical surveillance and maintenance operations, and, besides, it rises the risk of contaminating the personnel and environment. The research works conducted in INR Pitesti aim at transferring the activity of ion exchange resin waste to an inorganic support by acid stripping or bacterial degrading. In both methods the C-14 released as CO 2 is embodied on an inorganic solid support which is subsequently conditioned into a matrix adequate to final disposal. The retaining efficiency of CO 2 by a Ca(OH) 2 or Ba(OH) 2 solid column was established as well as the optimal waste-cement proportion. It was done by carrying out compression tests on Portland cement samples with different inclusion of CaCO 3 and BaCO 3 . The resulting composition diagram is shown. Optimal cement : waste ratio was found to equal 1 and 0.9 for CaCO 3 and BaCO 3 , respectively. The chemical stability of the cement-CaCO 3 or cement-BaCO 3 samples was determined by investigating swelling, cracking or braking phenomena, following immersion in distilled water, and by conducting leaching tests, as well. The leaching rates for the two materials were found to be 96 x 10 -4 gC/cm 2 ·day decreasing down to 3.0 x 10 -4 gC/cm 2 ·day in 35 days and 62 x 10 -4 gC/cm 2 ·day decreasing down to 4 x 10 -4 gC/cm 2 ·day in 12 days of exposure to de-mineralized water, respectively. Long term (4,000 years) evaluations showed that only 0.25% of the C-14 immobilized in the conditions described is released in the environment. Tests on degradation of the two samples immersed for 90 days, as well as the water absorption rate showed that both cement-CaCO 3 and cement-BaCO 3 are adequate

  11. Robust Nonnegative Patch Alignment for Dimensionality Reduction.

    Science.gov (United States)

    You, Xinge; Ou, Weihua; Chen, Chun Lung Philip; Li, Qiang; Zhu, Ziqi; Tang, Yuanyan

    2015-11-01

    Dimensionality reduction is an important method to analyze high-dimensional data and has many applications in pattern recognition and computer vision. In this paper, we propose a robust nonnegative patch alignment for dimensionality reduction, which includes a reconstruction error term and a whole alignment term. We use correntropy-induced metric to measure the reconstruction error, in which the weight is learned adaptively for each entry. For the whole alignment, we propose locality-preserving robust nonnegative patch alignment (LP-RNA) and sparsity-preserviing robust nonnegative patch alignment (SP-RNA), which are unsupervised and supervised, respectively. In the LP-RNA, we propose a locally sparse graph to encode the local geometric structure of the manifold embedded in high-dimensional space. In particular, we select large p -nearest neighbors for each sample, then obtain the sparse representation with respect to these neighbors. The sparse representation is used to build a graph, which simultaneously enjoys locality, sparseness, and robustness. In the SP-RNA, we simultaneously use local geometric structure and discriminative information, in which the sparse reconstruction coefficient is used to characterize the local geometric structure and weighted distance is used to measure the separability of different classes. For the induced nonconvex objective function, we formulate it into a weighted nonnegative matrix factorization based on half-quadratic optimization. We propose a multiplicative update rule to solve this function and show that the objective function converges to a local optimum. Several experimental results on synthetic and real data sets demonstrate that the learned representation is more discriminative and robust than most existing dimensionality reduction methods.

  12. Mechanical design in embryos: mechanical signalling, robustness and developmental defects.

    Science.gov (United States)

    Davidson, Lance A

    2017-05-19

    Embryos are shaped by the precise application of force against the resistant structures of multicellular tissues. Forces may be generated, guided and resisted by cells, extracellular matrix, interstitial fluids, and how they are organized and bound within the tissue's architecture. In this review, we summarize our current thoughts on the multiple roles of mechanics in direct shaping, mechanical signalling and robustness of development. Genetic programmes of development interact with environmental cues to direct the composition of the early embryo and endow cells with active force production. Biophysical advances now provide experimental tools to measure mechanical resistance and collective forces during morphogenesis and are allowing integration of this field with studies of signalling and patterning during development. We focus this review on concepts that highlight this integration, and how the unique contributions of mechanical cues and gradients might be tested side by side with conventional signalling systems. We conclude with speculation on the integration of large-scale programmes of development, and how mechanical responses may ensure robust development and serve as constraints on programmes of tissue self-assembly.This article is part of the themed issue 'Systems morphodynamics: understanding the development of tissue hardware'. © 2017 The Author(s).

  13. An Automatic Learning-Based Framework for Robust Nucleus Segmentation.

    Science.gov (United States)

    Xing, Fuyong; Xie, Yuanpu; Yang, Lin

    2016-02-01

    Computer-aided image analysis of histopathology specimens could potentially provide support for early detection and improved characterization of diseases such as brain tumor, pancreatic neuroendocrine tumor (NET), and breast cancer. Automated nucleus segmentation is a prerequisite for various quantitative analyses including automatic morphological feature computation. However, it remains to be a challenging problem due to the complex nature of histopathology images. In this paper, we propose a learning-based framework for robust and automatic nucleus segmentation with shape preservation. Given a nucleus image, it begins with a deep convolutional neural network (CNN) model to generate a probability map, on which an iterative region merging approach is performed for shape initializations. Next, a novel segmentation algorithm is exploited to separate individual nuclei combining a robust selection-based sparse shape model and a local repulsive deformable model. One of the significant benefits of the proposed framework is that it is applicable to different staining histopathology images. Due to the feature learning characteristic of the deep CNN and the high level shape prior modeling, the proposed method is general enough to perform well across multiple scenarios. We have tested the proposed algorithm on three large-scale pathology image datasets using a range of different tissue and stain preparations, and the comparative experiments with recent state of the arts demonstrate the superior performance of the proposed approach.

  14. Do clinicians receive adequate training to identify trafficked persons? A scoping review of NHS Foundation Trusts.

    Science.gov (United States)

    Thompson, Charles Dr; Mahay, Arun; Stuckler, David; Steele, Sarah

    2017-09-01

    We investigate whether physicians in secondary care in the English NHS receive adequate training to recognise and appropriately refer for services those persons suspected to be victims of human trafficking. Freedom of Information requests were sent to the 105 England's NHS Trusts delivering acute care in England. NHS Trusts providing secondary care in England. English NHS Trusts. We requested data about the training provided on human trafficking to clinicians, including the nature, delivery, and format of any education, and any planned training. A total of 89.5% of the 105 Trusts responded. Of these Trusts, 69% provide education to physicians on human trafficking, and a further 6% provide training but did not specify who received it. The majority of Trusts providing training did so within wider safeguarding provision (91%). Only one trust reported that it provides stand-alone training on trafficking to all its staff, including physicians. Within training offered by Trusts, 54% observed best practice providing training on the clinical indicators of trafficking, while 16% referenced the National Referral Mechanism. Amongst those not providing training, 39% of Trusts report provision is in development. Our results find that 25% of NHS Foundation Trusts appear to lack training for physicians around human trafficking. It is also of concern that of the Trusts who currently do not provide training, only 39% are developing training or planning to do so. There is an urgent need to review and update the scope of available training and bring it into alignment with current legislation.

  15. GENERIC APPROACH IN CHOICE OF ADEQUATE METHODOLOGY FOR THE ASSESSMENT OF IT INVESTMENTS

    Directory of Open Access Journals (Sweden)

    Melita Kozina

    2012-07-01

    Full Text Available Investments into information technology (IT, (hereinafter: IT investments havereached very high figures, which are still continually on the rise. IT potentials are being usedin an increasing number of ways. Various company managers have different approaches tothis issue. A large number of methods/models for the assessment of IT investments isavailable, so the question is posed of how to choose the adequate assessment category. Thesaid reasons have initiated a need for defining the generic approach in the choice ofadequate methodology for the assessment of IT investments, which was indeed the goal ofthis paper. General ideas to this approach stem from the fact that each IT investment has itspurpose and belongs to a certain type of IT investment (decision-making aspect whichdemands its relevant methodology for assessing IT investments. Two groups of demands(conditions have been defined in choosing relevant methodology. The first group pertains tomethodology analysis and determination of its compatibility with characteristics of thedefined decision-making aspect. The second group of conditions pertains to methodologyanalysis with respect to its possibilities (abilities of integrating quantity, quality and riskfactors of IT decision. Conducted field research shows that the assessment of IT investmentshas been done mainly using simpler methods/models and their combinations, and is focusedon quantity aspects of IT values.

  16. Improved ASTM G72 Test Method for Ensuring Adequate Fuel-to-Oxidizer Ratios

    Science.gov (United States)

    Juarez, Alfredo; Harper, Susana Tapia

    2016-01-01

    The ASTM G72/G72M-15 Standard Test Method for Autogenous Ignition Temperature of Liquids and Solids in a High-Pressure Oxygen-Enriched Environment is currently used to evaluate materials for the ignition susceptibility driven by exposure to external heat in an enriched oxygen environment. Testing performed on highly volatile liquids such as cleaning solvents has proven problematic due to inconsistent test results (non-ignitions). Non-ignition results can be misinterpreted as favorable oxygen compatibility, although they are more likely associated with inadequate fuel-to-oxidizer ratios. Forced evaporation during purging and inadequate sample size were identified as two potential causes for inadequate available sample material during testing. In an effort to maintain adequate fuel-to-oxidizer ratios within the reaction vessel during test, several parameters were considered, including sample size, pretest sample chilling, pretest purging, and test pressure. Tests on a variety of solvents exhibiting a range of volatilities are presented in this paper. A proposed improvement to the standard test protocol as a result of this evaluation is also presented. Execution of the final proposed improved test protocol outlines an incremental step method of determining optimal conditions using increased sample sizes while considering test system safety limits. The proposed improved test method increases confidence in results obtained by utilizing the ASTM G72 autogenous ignition temperature test method and can aid in the oxygen compatibility assessment of highly volatile liquids and other conditions that may lead to false non-ignition results.

  17. Hydrological functional unit identification - linking observables and concepts towards a minimal adequate catchment representation

    Science.gov (United States)

    Jackisch, C.

    2012-04-01

    Understanding catchment structures and properties as most probable result of past work during their evolution under the continuous depletion of gradients opens a connection of landscape properties to dominating processes. While a qualitative description from the expert's perspective can comprehend most of these; a distinct objective delineation into functional units, their topology and their connectivity appears far more problematic as a) spatio-temporal scale, b) degrees of freedom and c) aspects of self-organisation have to be brought in accordance. Our study highlights several conceptual approaches aiming to link hydrological landscape understanding, observation and modelling. Moreover, a GIS-based case study for the Attert basin is presented, which shows that from a multitude of possible class combinations, already very few cover the vast majority of the catchment. Consequently, dominating processes, prevailing topologies, most insightful data demands and possible non ad hoc model representations are outlined. The result is a step towards a minimal adequate catchment representation. To base this on physical descriptions with truly observable parameters, we further revise most insightful data for functional unit identification and observation and if and how it can be derived in the landscape and from products available.

  18. Adequate Funding for Primary Education in the Artibonite Department of Haiti

    Science.gov (United States)

    Nylund, Clayton Carl

    Since its formation following a slave revolution in 1804, the Republic of Haiti has a long history of political instability, civil unrest and poverty. As of 2015, Haiti's gross domestic product (GDP) was US1,732, per capita, making it the poorest country in the Western Hemisphere. Haiti's education sector was no exception to this sparsity, receiving only 2.5 percent of the nation's overall GDP. The purpose of this study was to determine adequate funding for Haitian primary schools based upon mathematical achievement levels and the professional judgment of site-based administrators. A Florida Comprehensive Assessment Test (FCAT), originally administered to Florida's third-grade students in 2006, was utilized to determine mathematical achievement. In 2015, the translated FCAT was administered to 207 students, enrolled in four schools, located in the lower Artibonite department of Haiti. The results indicated that the sample answered sixteen of the forty mathematics questions correctly, on average. Based on these results, the four site-based administrators recommended the funding amounts necessary to increase mathematical achievement by 15 percent. The average annual amounts, in US dollars, included 461 per teacher salary, a 540 administrative salary, 40 per student for instructional materials, 367 per student for meals, and 37 per student for uniforms.

  19. Are Nutritional Care Adequate for Elderly Hospitalized Patients? A Cross-Sectional Study

    Directory of Open Access Journals (Sweden)

    Helene Kjøllesdal Eide

    2016-12-01

    Full Text Available This article assesses nutritional care in identifying and treating nutritional risk in elderly hospitalized patients. A cross-sectional study was conducted at a large Norwegian University hospital in the period 2011 to 2013. Data on nutritional risk and care for elderly patients (≥70 years without dementia were collected at 20 wards by 173 second-year nursing students in acute-care clinical studies. A stratified sampling technique was utilized to improve the representativeness of the sample. In total, 508 patients (48.8% women with a mean age of 79.6 years participated. The internationally and nationally recommended nutritional care was not implemented at the hospital, suggesting that nutritional care for elderly hospitalized patients was not adequate. This implies that the majority of the elderly patients nutritionally at risk are neither identified nor treated according to their needs. The article highlights the importance of having systematic nutritional care practices to make it possible for the hospital ward staff to routinely identify nutritional risk and initiate appropriate nutritional treatment measures.

  20. Improvement of adequate use of warfarin for the elderly using decision tree-based approaches.

    Science.gov (United States)

    Liu, K E; Lo, C-L; Hu, Y-H

    2014-01-01

    Due to the narrow therapeutic range and high drug-to-drug interactions (DDIs), improving the adequate use of warfarin for the elderly is crucial in clinical practice. This study examines whether the effectiveness of using warfarin among elderly inpatients can be improved when machine learning techniques and data from the laboratory information system are incorporated. Having employed 288 validated clinical cases in the DDI group and 89 cases in the non-DDI group, we evaluate the prediction performance of seven classification techniques, with and without an Adaptive Boosting (AdaBoost) algorithm. Measures including accuracy, sensitivity, specificity and area under the curve are used to evaluate model performance. Decision tree-based classifiers outperform other investigated classifiers in all evaluation measures. The classifiers supplemented with AdaBoost can generally improve the performance. In addition, weight, congestive heart failure, and gender are among the top three critical variables affecting prediction accuracy for the non-DDI group, while age, ALT, and warfarin doses are the most influential factors for the DDI group. Medical decision support systems incorporating decision tree-based approaches improve predicting performance and thus may serve as a supplementary tool in clinical practice. Information from laboratory tests and inpatients' history should not be ignored because related variables are shown to be decisive in our prediction models, especially when the DDIs exist.

  1. Toward Adequate Operation of Amorphous Oxide Thin-Film Transistors for Low-Concentration Gas Detection.

    Science.gov (United States)

    Kim, Kyung Su; Ahn, Cheol Hyoun; Jung, Sung Hyeon; Cho, Sung Woon; Cho, Hyung Koun

    2018-03-28

    We suggest the use of a thin-film transistor (TFT) composed of amorphous InGaZnO (a-IGZO) as a channel and a sensing layer for low-concentration NO 2 gas detection. Although amorphous oxide layers have a restricted surface area when reacting with NO 2 gas, such TFT sensors have incomparable advantages in the aspects of electrical stability, large-scale uniformity, and the possibility of miniaturization. The a-IGZO thin films do not possess typical reactive sites and grain boundaries, so that the variation in drain current of the TFTs strictly originates from oxidation reaction between channel surface and NO 2 gas. Especially, the sensing data obtained from the variation rate of drain current makes it possible to monitor efficiently and quickly the variation of the NO 2 concentration. Interestingly, we found that enhancement-mode TFT (EM-TFT) allows discrimination of the drain current variation rate at NO 2 concentrations ≤10 ppm, whereas a depletion-mode TFT is adequate for discriminating NO 2 concentrations ≥10 ppm. This discrepancy is attributed to the ratio of charge carriers contributing to gas capture with respect to total carriers. This capacity for the excellent detection of low-concentration NO 2 gas can be realized through (i) three-terminal TFT gas sensors using amorphous oxide, (ii) measurement of the drain current variation rate for high selectivity, and (iii) an EM mode driven by tuning the electrical conductivity of channel layers.

  2. Alcoholic pancreatitis in rats fed ethanol in a nutritionally adequate liquid diet.

    Science.gov (United States)

    Singh, M

    1987-01-01

    In an effort to develop a model of chronic alcoholic pancreatitis in Sprague-Dawley rats fed a nutritionally adequate diet, 3 groups of 15 animals each were fed Wayne Rodent-Blox ad libitum, Lieber-DeCarli diet with 40% of carbohydrate calories replaced by ethanol ad libitum and isocaloric amounts of Lieber-DeCarli diet respectively for a period of 18 months. Rats were anesthetized and basal and secretin-stimulated pancreatic juice was obtained. Pancreatic glands were isolated and divided into portions for histology, biochemical analyses, and cell fractionation. The homogenate, zymogen granule fraction, mitochondrial-lysosomal fraction, microsomal fraction and postmicrosomal supernatant as well as aliquots of pancreatic juice were analyzed for cathepsin B, acid phosphatase, beta-D-glucoronidase, arylsulphatase and leucine naphthylamidase. All of the ethanol-fed animals developed morphological changes akin to human chronic pancreatitis. There were focal areas of parenchymal degeneration with fibrosis, protein plug formation and tubular complexes. In the pancreatic tissue of animals fed ethanol, total protein, trypsinogen (and free trypsin) were increased and amylase was decreased. While acid phosphatase was increased in all of the particulate fractions, cathepsin B was increased in the zymogen granule and mitochondrial-lysosomal fractions. Basal and post-secretin pancreatic juice did not show a significant increase in digestive or lysosomal enzymes. It is suggested that focal degenerative changes may be due to trypsin generated by intracellular activation of digestive enzymes by lysosomal enzyme cathepsin B.

  3. Aurally-adequate time-frequency analysis for scattered sound in auditoria

    Science.gov (United States)

    Norris, Molly K.; Xiang, Ning; Kleiner, Mendel

    2005-04-01

    The goal of this work was to apply an aurally-adequate time-frequency analysis technique to the analysis of sound scattering effects in auditoria. Time-frequency representations were developed as a motivated effort that takes into account binaural hearing, with a specific implementation of interaural cross-correlation process. A model of the human auditory system was implemented in the MATLAB platform based on two previous models [A. Härmä and K. Palomäki, HUTear, Espoo, Finland; and M. A. Akeroyd, A. Binaural Cross-correlogram Toolbox for MATLAB (2001), University of Sussex, Brighton]. These stages include proper frequency selectivity, the conversion of the mechanical motion of the basilar membrane to neural impulses, and binaural hearing effects. The model was then used in the analysis of room impulse responses with varying scattering characteristics. This paper discusses the analysis results using simulated and measured room impulse responses. [Work supported by the Frank H. and Eva B. Buck Foundation.

  4. Household-level technologies to improve the availability and preparation of adequate and safe complementary foods.

    Science.gov (United States)

    Mensah, Patience; Tomkins, Andrew

    2003-03-01

    Plant-based complementary foods are the main source of nutrients for many young children in developing countries. They may, however, present problems in providing nutritionally adequate and safe diets for older infants and young children. The high starch content leads to low-nutrient diets that are bulky and dense, with high levels of antinutritive factors such as phytates, tannins, lectins, and enzyme inhibitors. Phytates impair mineral bioavailability, lectins interfere with intestinal structure, and enzyme inhibitors inhibit digestive enzymes. In addition, there is often microbial contamination, which leads to diarrhea, growth-faltering, and impaired development, and the presence of chemical contaminants may lead to neurological disease and goiter. The fact that some fruits containing carotenoids are only available seasonally contributes to the vulnerability of children receiving predominantly plant-based diets. Traditional household food technologies have been used for centuries to improve the quality and safety of complementary foods. These include dehulling, peeling, soaking, germination, fermentation, and drying. While modern communities tend to reject these technologies in favor of more convenient fast-food preparations, there is now a resurgence of interest in older technologies as a possible means of improving the quality and safety of complementary foods when the basic diet cannot be changed for economic reasons. This paper describes the biology, safety, practicability, and acceptability of these traditional processes at the household or community level, as well as the gaps in research, so that more effective policies and programs can be implemented to improve the quality and safety of complementary foods.

  5. External skeletal robusticity of children and adolescents - European references from birth to adulthood and international comparisons.

    Science.gov (United States)

    Mumm, Rebekka; Godina, Elena; Koziel, Slawomir; Musalek, Martin; Sedlak, Petr; Wittwer-Backofen, Ursula; Hesse, Volker; Dasgupta, Parasmani; Henneberg, Maciej; Scheffler, Christiane

    2018-02-20

    Background: In our modern world, the way of life in nutritional and activity behaviour has changed. As a consequence, parallel trends of an epidemic of overweight and a decline in external skeletal robusticity are observed in children and adolescents. Aim: We aim to develop reference centiles for external skeletal robusticity of European girls and boys aged 0 to 18 years using the Frame Index as an indicator and identify population specific age-related patterns. Methods: We analysed cross-sectional & longitudinal data on body height and elbow breadth of boys and girls from Europe (0-18 years, n = 41.679), India (7-18 years, n = 3.297) and South Africa (3-18 years, n = 4.346). As an indicator of external skeletal robusticity Frame Index after Frisancho (1990) was used. We developed centiles for boys and girls using the LMS-method and its extension. Results: Boys have greater external skeletal robusticity than girls. Whereas in girls Frame Index decreases continuously during growth, an increase of Frame Index from 12 to 16 years in European boys can be observed. Indian and South African boys are almost similar in Frame Index to European boys. In girls, the pattern is slightly different. Whereas South African girls are similar to European girls, Indian girls show a lesser external skeletal robusticity. Conclusion: Accurate references for external skeletal robusticity are needed to evaluate if skeletal development is adequate per age. They should be used to monitor effects of changes in way of life and physical activity levels in children and adolescents to avoid negative health outcomes like osteoporosis and arthrosis.

  6. Cerebral cortex dose sparing for glioblastoma patients: IMRT versus robust treatment planning.

    Science.gov (United States)

    Exeli, Ann-Katrin; Kellner, Daniel; Exeli, Lukas; Steininger, Phil; Wolf, Frank; Sedlmayer, Felix; Deutschmann, Heinz

    2018-02-06

    To date, patients with glioblastoma still have a bad median overall survival rate despite radiation dose-escalation and combined modality treatment. Neurocognitive decline is a crucial adverse event which may be linked to high doses to the cortex. In a planning study, we investigated the impact of dose constraints to the cerebral cortex and its relation to the organs at risk for glioblastoma patients. Cortical sparing was implemented into the optimization process for two planning approaches: classical intensity-modulated radiotherapy (IMRT) and robust treatment planning. The plans with and without objectives for cortex sparing where compared based on dose-volume histograms (DVH) data of the main organs at risk. Additionally the cortex volume above a critical threshold of 28.6 Gy was elaborated. Furthermore, IMRT plans were compared with robust treatment plans regarding potential cortex sparing. Cortical dose constraints result in a statistically significant reduced cerebral cortex volume above 28.6 Gy without negative effects to the surrounding organs at risk independently of the optimization technique. For IMRT we found a mean volume reduction of doses beyond the threshold of 19%, and 16% for robust treatment planning, respectively. Robust plans delivered sharper dose gradients around the target volume in an order of 3 - 6%. Aside from that the integration of cortical sparing into the optimization process has the potential to reduce the dose around the target volume (4 - 8%). We were able to show that dose to the cerebral cortex can be significantly reduced both with robust treatment planning and IMRT while maintaining clinically adequate target coverage and without corrupting any organ at risk. Robust treatment plans delivered more conformal plans compared to IMRT and were superior in regards to cortical sparing.

  7. Does limited data availability prevent adequate water use estimates on farm scale?

    Science.gov (United States)

    Kayatz, Benjamin; Kuster, Benjamin; Percy, Barbara; Hillier, Jonathan; Freese, Dirk; Wattenbach, Martin

    2015-04-01

    Increasing food production for a growing world population and at the same time mitigating climate change as well as adapting to its consequences is one of the key global challenges. Therefore producing crops with fewer resources such as water and fertilizers and less emissions of greenhouse gases is an important question that has to be answered on farm scale. The cool farm tool (CFT) is a farm scale emission calculator and was developed in 2010 to help farmers to reduce their carbon footprint. In order to adapt to future climate change an easy to use and at the same time robust water footprinting tool is needed for the CFT to take a more holistic approach on environmental sustainability. However data on farm level is often scarce. We investigated the effect of limited data on actual evapotranspiration using the FAO56 standard to assess the quality of farm water footprint estimates. Calculations are based on various agricultural sites from the Fluxnet database and estimates are compared to eddy covariance measurements. Results show that higher data availability is not directly linked to more accurate estimates of actual evapotranspiration. Estimates based only on temperature and relative humidity are still able to reproduce daily patterns. However cumulative values over one growing season show a considerable offset to eddy covariance observations for all data input levels. Finding the optimum between data requirements and an accuracy that fulfills farmer needs is crucial. Engagement of farmers and using a global network as the Fluxnet database will help to achieve this goal.

  8. Early prenatal syphilis

    Directory of Open Access Journals (Sweden)

    Santosh Rathod

    2010-01-01

    Full Text Available Syphilis in pregnancy still remains a challenge despite the availability of adequate diagnostic tests for serological screening and penicillin therapy. We report a case of 2 month old female infant who presented with runny nose, papulosquamous lesions over both palms and soles and perianal erosions since 1 month after birth. Cutaneous examination revealed moist eroded areas in the perianal region and fine scaly lesions over palms and soles. Radiograph of both upper limbs and limbs revealed early periosteal changes in lower end of humerus and lower end of tibia. Diagnosis of early pre-natal syphilis was confirmed by Child′s Serum Rapid Plasma Reagin Antibody test [S.RPR] being positive with 1:64 dilution while that of mother was 1:8.

  9. Robust mutant strain design by pessimistic optimization.

    Science.gov (United States)

    Apaydin, Meltem; Xu, Liang; Zeng, Bo; Qian, Xiaoning

    2017-10-03

    Flux Balance Analysis (FBA) based mathematical modeling enables in silico prediction of systems behavior for genome-scale metabolic networks. Computational methods have been derived in the FBA framework to solve bi-level optimization for deriving "optimal" mutant microbial strains with targeted biochemical overproduction. The common inherent assumption of these methods is that the surviving mutants will always cooperate with the engineering objective by overproducing the maximum desired biochemicals. However, it has been shown that this optimistic assumption may not be valid in practice. We study the validity and robustness of existing bi-level methods for strain optimization under uncertainty and non-cooperative environment. More importantly, we propose new pessimistic optimization formulations: P-ROOM and P-OptKnock, aiming to derive robust mutants with the desired overproduction under two different mutant cell survival models: (1) ROOM assuming mutants have the minimum changes in reaction fluxes from wild-type flux values, and (2) the one considered by OptKnock maximizing the biomass production yield. When optimizing for desired overproduction, our pessimistic formulations derive more robust mutant strains by considering the uncertainty of the cell survival models at the inner level and the cooperation between the outer- and inner-level decision makers. For both P-ROOM and P-OptKnock, by converting multi-level formulations into single-level Mixed Integer Programming (MIP) problems based on the strong duality theorem, we can derive exact optimal solutions that are highly scalable with large networks. Our robust formulations P-ROOM and P-OptKnock are tested with a small E. coli core metabolic network and a large-scale E. coli iAF1260 network. We demonstrate that the original bi-level formulations (ROOM and OptKnock) derive mutants that may not achieve the predicted overproduction under uncertainty and non-cooperative environment. The knockouts obtained by the

  10. Reliability-Based Robustness Analysis for a Croatian Sports Hall

    DEFF Research Database (Denmark)

    Čizmar, Dean; Kirkegaard, Poul Henning; Sørensen, John Dalsgaard

    2011-01-01

    This paper presents a probabilistic approach for structural robustness assessment for a timber structure built a few years ago. The robustness analysis is based on a structural reliability based framework for robustness and a simplified mechanical system modelling of a timber truss system...... is expressed and evaluated by a robustness index. Next, the robustness is assessed using system reliability indices where the probabilistic failure model is modelled by a series system of parallel systems....

  11. Robustness of Linear Systems towards Multi-Dissipative Pertubations

    DEFF Research Database (Denmark)

    Thygesen, Uffe Høgsbro; Poulsen, Niels Kjølstad

    1997-01-01

    We consider the question of robust stability of a linear time invariant plant subject to dynamic perturbations, which are dissipative in the sense of Willems with respect to several quadratic supply rates. For instance, parasitic dynamics are often both small gain and passive. We reduce several...... robustness analysis questions to linear matrix inequalities: robust stability, robust H2 performance and robust performance in presence of disturbances with finite signal-to-noise ratios...

  12. Robust Reed Solomon Coded MPSK Modulation

    Directory of Open Access Journals (Sweden)

    Emir M. Husni

    2014-10-01

    Full Text Available In this paper, construction of partitioned Reed Solomon coded modulation (RSCM, which is robust for the additive white Gaussian noise channel and a Rayleigh fading channel, is investigated. By matching configuration of component codes with the channel characteristics, it is shown that this system is robust for the Gaussian and a Rayleigh fading channel. This approach is compared with non-partitioned RSCM, a Reed Solomon code combined with an MPSK signal set using Gray mapping; and block coded MPSK modulation using binary codes, Reed Muller codes. All codes use hard decision decoding algorithm. Simulation results for these schemes show that RSCM based on set partitioning performs better than those that are not based on set partitioning and Reed Muller Coded Modulation across a wide range of conditions. The novel idea here is that in the receiver, we use a rotated 2^(m+1-PSK detector if the transmitter uses a 2^m-PSK modulator.

  13. Robust Multiparty Computation with Linear Communication Complexity

    DEFF Research Database (Denmark)

    Hirt, Martin; Nielsen, Jesper Buus

    2006-01-01

    We present a robust multiparty computation protocol. The protocol is for the cryptographic model with open channels and a poly-time adversary, and allows n parties to actively securely evaluate any poly-sized circuit with resilience t communication complexity in bits over the point......-to-point channels is (Sn+n), where S is the size of the circuit being securely evaluated, κ is the security parameter and is the communication complexity of one broadcast of a κ-bit value. This means the average number of bits sent and received by a single party is (S+), which is almost independent of the number...... of participating parties. This is the first robust multiparty computation protocol with this property....

  14. Robust lyapunov controller for uncertain systems

    KAUST Repository

    Laleg-Kirati, Taous-Meriem

    2017-02-23

    Various examples of systems and methods are provided for Lyapunov control for uncertain systems. In one example, a system includes a process plant and a robust Lyapunov controller configured to control an input of the process plant. The robust Lyapunov controller includes an inner closed loop Lyapunov controller and an outer closed loop error stabilizer. In another example, a method includes monitoring a system output of a process plant; generating an estimated system control input based upon a defined output reference; generating a system control input using the estimated system control input and a compensation term; and adjusting the process plant based upon the system control input to force the system output to track the defined output reference. An inner closed loop Lyapunov controller can generate the estimated system control input and an outer closed loop error stabilizer can generate the system control input.

  15. Communicating via robust synchronization of chaotic lasers

    Energy Technology Data Exchange (ETDEWEB)

    Lopez-Gutierrez, R.M. [Engineering Faculty, Baja California Autonomous University (UABC), Km. 103 Carret. Tij-Ens., 22860 Ensenada, B.C. (Mexico); Posadas-Castillo, C. [Engineering Faculty, Baja California Autonomous University (UABC), Km. 103 Carret. Tij-Ens., 22860 Ensenada, B.C. (Mexico); FIME, Autonomous University of Nuevo Leon (UANL), Pedro de Alba, S.N., Cd. Universitaria, San Nicolas de los Garza, NL (Mexico); Lopez-Mancilla, D. [Departamento de Ciencias Exactas y Tecnologicas, Centro Universitario de los Lagos, Universidad de Guadalajara (CULagos-UdeG), Enrique Diaz de Leon s/n, 47460 Lagos de Moreno, Jal. (Mexico); Cruz-Hernandez, C. [Electronics and Telecommunications Department, Scientific Research and Advanced Studies of Ensenada (CICESE), Km. 107 Carret. Tij-Ens., 22860 Ensenada, B.C. (Mexico)], E-mail: ccruz@cicese.mx

    2009-10-15

    In this paper, the robust synchronization problem for coupled chaotic Nd:YAG lasers is addressed. We resort to complex systems theory to achieve chaos synchronization. Based on stability theory, it is shown that the state trajectories of the perturbed error synchronization are ultimately bounded, provided the unperturbed synchronization error system is exponentially stable, and some conditions on the bounds of the perturbation terms are satisfied. So that, encoding, transmission, and decoding in chaotic optical communications are presented. We analyze the transmission and recovery of encrypted information when parameter mismatches are considered. Computer simulations are provided to show the effectiveness of this robustness synchronization property, we present the encrypted transmission of image messages, and we show that, the transmitted image is faithfully recovered.

  16. Adding query privacy to robust DHTs

    DEFF Research Database (Denmark)

    Backes, Michael; Goldberg, Ian; Kate, Aniket

    2012-01-01

    Interest in anonymous communication over distributed hash tables (DHTs) has increased in recent years. However, almost all known solutions solely aim at achieving sender or requestor anonymity in DHT queries. In many application scenarios, it is crucial that the queried key remains secret from...... intermediate peers that (help to) route the queries towards their destinations. In this paper, we satisfy this requirement by presenting an approach for providing privacy for the keys in DHT queries. We use the concept of oblivious transfer (OT) in communication over DHTs to preserve query privacy without...... compromising spam resistance. Although our OT-based approach can work over any DHT, we concentrate on robust DHTs that can tolerate Byzantine faults and resist spam. We choose the best-known robust DHT construction, and employ an efficient OT protocol well-suited for achieving our goal of obtaining query...

  17. Adding Query Privacy to Robust DHTs

    DEFF Research Database (Denmark)

    Backes, Michael; Goldberg, Ian; Kate, Aniket

    2011-01-01

    Interest in anonymous communication over distributed hash tables (DHTs) has increased in recent years. However, almost all known solutions solely aim at achieving sender or requestor anonymity in DHT queries. In many application scenarios, it is crucial that the queried key remains secret from...... intermediate peers that (help to) route the queries towards their destinations. In this paper, we satisfy this requirement by presenting an approach for providing privacy for the keys in DHT queries. We use the concept of oblivious transfer (OT) in communication over DHTs to preserve query privacy without...... compromising spam resistance. Although our OT-based approach can work over any DHT, we concentrate on communication over robust DHTs that can tolerate Byzantine faults and resist spam. We choose the best-known robust DHT construction, and employ an efficient OT protocol well-suited for achieving our goal...

  18. Model predictive control classical, robust and stochastic

    CERN Document Server

    Kouvaritakis, Basil

    2016-01-01

    For the first time, a textbook that brings together classical predictive control with treatment of up-to-date robust and stochastic techniques. Model Predictive Control describes the development of tractable algorithms for uncertain, stochastic, constrained systems. The starting point is classical predictive control and the appropriate formulation of performance objectives and constraints to provide guarantees of closed-loop stability and performance. Moving on to robust predictive control, the text explains how similar guarantees may be obtained for cases in which the model describing the system dynamics is subject to additive disturbances and parametric uncertainties. Open- and closed-loop optimization are considered and the state of the art in computationally tractable methods based on uncertainty tubes presented for systems with additive model uncertainty. Finally, the tube framework is also applied to model predictive control problems involving hard or probabilistic constraints for the cases of multiplic...

  19. Robust control of the activated sludge process.

    Science.gov (United States)

    David, R; Vande Wouwer, A; Vasel, J-L; Queinnec, I

    2009-01-01

    In this work, a robust control strategy is proposed for maintaining the oxygen concentration in the aerobic tank and the pollutant, i.e., ammonium, nitrate, nitrite, concentrations at acceptable levels in the effluent water at the outlet of the activated sludge process. To this end, the Activated Sludge Model no. 1 (ASM1) is first reduced using biological arguments and a singular perturbation method, and a simplified model of the secondary settler is included. In contrast with previous studies that make use of piecewise linear models, an average operating point is evaluated using available data (here data from the COST Action 624) and the reduced-order model is linearized around it using standard techniques. Finally, a H(2) robust control strategy acting on the oxygen injection and the recirculated flow rate is designed and tested in simulation. 2009 American Institute of Chemical Engineers

  20. Communicating via robust synchronization of chaotic lasers

    International Nuclear Information System (INIS)

    Lopez-Gutierrez, R.M.; Posadas-Castillo, C.; Lopez-Mancilla, D.; Cruz-Hernandez, C.

    2009-01-01

    In this paper, the robust synchronization problem for coupled chaotic Nd:YAG lasers is addressed. We resort to complex systems theory to achieve chaos synchronization. Based on stability theory, it is shown that the state trajectories of the perturbed error synchronization are ultimately bounded, provided the unperturbed synchronization error system is exponentially stable, and some conditions on the bounds of the perturbation terms are satisfied. So that, encoding, transmission, and decoding in chaotic optical communications are presented. We analyze the transmission and recovery of encrypted information when parameter mismatches are considered. Computer simulations are provided to show the effectiveness of this robustness synchronization property, we present the encrypted transmission of image messages, and we show that, the transmitted image is faithfully recovered.

  1. Reliability and Robustness Evaluation of Timber Structures

    DEFF Research Database (Denmark)

    Cizmar, Dean; Sørensen, John Dalsgaard; Kirkegaard, Poul Henning

    In the last few decades there have been intensely research concerning reliability of timber structures. This is primarily because there is an increased focus on society on sustainability and environmental aspects. Modern timber as a building material is also being competitive compared to concrete...... and steel. However, reliability models applied to timber were always related to individual components but not the systems. as any real structure is a complex system, system behaviour must be of a particular interest. In the chapter 1 of this document an overview of stochastic models for strength and loads...... (deterministic, probabilistic and risk based approaches) of the robustness are given. Chapter 3 deals more detailed with the robustness of timber structures....

  2. Robust photometric stereo using structural light sources

    Science.gov (United States)

    Han, Tian-Qi; Cheng, Yue; Shen, Hui-Liang; Du, Xin

    2014-05-01

    We propose a robust photometric stereo method by using structural arrangement of light sources. In the arrangement, light sources are positioned on a planar grid and form a set of collinear combinations. The shadow pixels are detected by adaptive thresholding. The specular highlight and diffuse pixels are distinguished according to their intensity deviations of the collinear combinations, thanks to the special arrangement of light sources. The highlight detection problem is cast as a pattern classification problem and is solved using support vector machine classifiers. Considering the possible misclassification of highlight pixels, the ℓ1 regularization is further employed in normal map estimation. Experimental results on both synthetic and real-world scenes verify that the proposed method can robustly recover the surface normal maps in the case of heavy specular reflection and outperforms the state-of-the-art techniques.

  3. Doubly Constrained Robust Blind Beamforming Algorithm

    Directory of Open Access Journals (Sweden)

    Xin Song

    2013-01-01

    Full Text Available We propose doubly constrained robust least-squares constant modulus algorithm (LSCMA to solve the problem of signal steering vector mismatches via the Bayesian method and worst-case performance optimization, which is based on the mismatches between the actual and presumed steering vectors. The weight vector is iteratively updated with penalty for the worst-case signal steering vector by the partial Taylor-series expansion and Lagrange multiplier method, in which the Lagrange multipliers can be optimally derived and incorporated at each step. A theoretical analysis for our proposed algorithm in terms of complexity cost, convergence performance, and SINR performance is presented in this paper. In contrast to the linearly constrained LSCMA, the proposed algorithm provides better robustness against the signal steering vector mismatches, yields higher signal captive performance, improves greater array output SINR, and has a lower computational cost. The simulation results confirm the superiority of the proposed algorithm on beampattern control and output SINR enhancement.

  4. Robust facility location: Hedging against failures

    International Nuclear Information System (INIS)

    Hernandez, Ivan; Emmanuel Ramirez-Marquez, Jose; Rainwater, Chase; Pohl, Edward; Medal, Hugh

    2014-01-01

    While few companies would be willing to sacrifice day-to-day operations to hedge against disruptions, designing for robustness can yield solutions that perform well before and after failures have occurred. Through a multi-objective optimization approach this paper provides decision makers the option to trade-off total weighted distance before and after disruptions in the Facility Location Problem. Additionally, this approach allows decision makers to understand the impact on the opening of facilities on total distance and on system robustness (considering the system as the set of located facilities). This approach differs from previous studies in that hedging against failures is done without having to elicit facility failure probabilities concurrently without requiring the allocation of additional hardening/protections resources. The approach is applied to two datasets from the literature

  5. Robust Reconfiguration of A Distribution System

    Energy Technology Data Exchange (ETDEWEB)

    Moradzadeh, Benyamin [University of Tennessee, Knoxville (UTK); Tomsovic, Kevin [University of Tennessee, Knoxville (UTK)

    2017-01-01

    In this paper, a robust reconfiguration approach based on Mixed Integer Programming (MIP) is proposed to minimize loss in distribution systems. A Depth-First Search (DFS) algorithm to enumerate possible loops provides radiality constraint. This provides a general solution to the radiality constraint for distribution system reconfiguration/expansion problems. Still, imprecision and ambiguity in net loads, i.e. load minus renewable generation, due to lack of sufficient measurements and high utilization of demand response programs and renewable resources, creates challenges for effective reconfiguration. Deterministic optimization of reconfiguration may no lead to optimal/feasible results. Two methods to address these uncertainties are introduced in this paper: one, based on a stochastic MIP (SMIP) formulation and two, based on a fuzzy MIP (FMIP) formulation. Case studies demonstrate the robustness and efficiency of the proposed reconfiguration methods.

  6. Generalized Correntropy for RobustAdaptive Filtering

    Science.gov (United States)

    Chen, Badong; Xing, Lei; Zhao, Haiquan; Zheng, Nanning; Principe, Jose C.

    2016-07-01

    As a robust nonlinear similarity measure in kernel space, correntropy has received increasing attention in domains of machine learning and signal processing. In particular, the maximum correntropy criterion (MCC) has recently been successfully applied in robust regression and filtering. The default kernel function in correntropy is the Gaussian kernel, which is, of course, not always the best choice. In this work, we propose a generalized correntropy that adopts the generalized Gaussian density (GGD) function as the kernel (not necessarily a Mercer kernel), and present some important properties. We further propose the generalized maximum correntropy criterion (GMCC), and apply it to adaptive filtering. An adaptive algorithm, called the GMCC algorithm, is derived, and the mean square convergence performance is studied. We show that the proposed algorithm is very stable and can achieve zero probability of divergence (POD). Simulation results confirm the theoretical expectations and demonstrate the desirable performance of the new algorithm.

  7. Prediction of Adequate Prenatal Care Utilization Based on the Extended Parallel Process Model.

    Science.gov (United States)

    Hajian, Sepideh; Imani, Fatemeh; Riazi, Hedyeh; Salmani, Fatemeh

    2017-10-01

    Pregnancy complications are one of the major public health concerns. One of the main causes of preventable complications is the absence of or inadequate provision of prenatal care. The present study was conducted to investigate whether Extended Parallel Process Model's constructs can predict the utilization of prenatal care services. The present longitudinal prospective study was conducted on 192 pregnant women selected through the multi-stage sampling of health facilities in Qeshm, Hormozgan province, from April to June 2015. Participants were followed up from the first half of pregnancy until their childbirth to assess adequate or inadequate/non-utilization of prenatal care services. Data were collected using the structured Risk Behavior Diagnosis Scale. The analysis of the data was carried out in SPSS-22 using one-way ANOVA, linear regression and logistic regression analysis. The level of significance was set at 0.05. Totally, 178 pregnant women with a mean age of 25.31±5.42 completed the study. Perceived self-efficacy (OR=25.23; Pprenatal care. Husband's occupation in the labor market (OR=0.43; P=0.02), unwanted pregnancy (OR=0.352; Pcare for the minors or elderly at home (OR=0.35; P=0.045) were associated with lower odds of receiving prenatal care. The model showed that when perceived efficacy of the prenatal care services overcame the perceived threat, the likelihood of prenatal care usage will increase. This study identified some modifiable factors associated with prenatal care usage by women, providing key targets for appropriate clinical interventions.

  8. The Goal of Adequate Nutrition: Can It Be Made Affordable, Sustainable, and Universal?

    Directory of Open Access Journals (Sweden)

    Ian McFarlane

    2016-11-01

    Full Text Available Until about 1900, large proportions of the world population endured hunger and poverty. The 20th century saw world population increase from 1.6 to 6.1 billion, accompanied and to some extent made possible by rapid improvements in health standards and food supply, with associated advances in agricultural and nutrition sciences. In this paper, I use the application of linear programming (LP in preparation of rations for farm animals to illustrate a method of calculating the lowest cost of a human diet selected from locally available food items, constrained to provide recommended levels of food energy and nutrients; then, to find a realistic minimum cost, I apply the further constraint that the main sources of food energy in the costed diet are weighted in proportion to the actual reported consumption of food items in that area. Worldwide variations in dietary preferences raise the issue as to the sustainability of popular dietary regimes, and the paper reviews the factors associated with satisfying requirements for adequate nutrition within those regimes. The ultimate physical constraints on food supply are described, together with the ways in which climate change may affect those constraints. During the 20th century, food supply increased sufficiently in most areas to keep pace with the rapid increase in world population. Many challenges will need to be overcome if food supply is to continue to meet demand, and those challenges are made more severe by rising expectations of quality of life in the developing world, as well as by the impacts of climate change on agriculture and aquaculture.

  9. Nutrition intervention and adequate hygiene practices to improve iron status of vulnerable preschool Burkinabe children.

    Science.gov (United States)

    Sanou, Dia; Turgeon-O'Brien, Huguette; Desrosiers, Thérèse

    2010-01-01

    To determine the impact of an intervention that combined an increase in dietary and bioavailable iron intakes and an improvement in hygiene behaviors on the iron status of preschool children from Burkina Faso. Thirty-three orphans and vulnerable children from 11 families who were 1-6 y old, were non-anemic, or had mild to moderate anemia were enrolled in an 18-wk trial. Using the probability approach for planning diets in an assisted-living facility, bioavailable iron intake was increased from 0.4 to 0.9 mg/d by increasing the amounts of meat and citrus fruits and by adding iron-rich condiments to the diet, for an estimated cost of U.S. $0.59/mo. Hygiene behaviors were modified by implementing hand-washing before meals and by the use of individual plates for meals. Iron status indicators were measured twice and means at enrollment and after intervention were compared. After intervention, hemoglobin concentration increased from 98.7 to 103.8 g/L (P=0.006). There was a decrease in total iron binding capacity (107 to 91 micromol/L, P=0.05) and a marginal increase in transferrin saturation (13% to 17%, P=0.06). Significant improvement was not observed for serum ferritin concentration or prevalence of depleted iron stores, likely due to the confounding effect of infection. Anemia and iron-deficiency anemia were decreased from 64% to 30% and from 61% to 30%, respectively. Dietary modification associated with adequate hygiene behaviors could be a relevant strategy to control iron deficiency and anemia in areas where infection is a major health problem.

  10. Adequate plasma drug concentrations suggest that amoxicillin can be administered by continuous infusion using elastomeric pumps.

    Science.gov (United States)

    Arensdorff, Lyne; Boillat-Blanco, Noémie; Decosterd, Laurent; Buclin, Thierry; de Vallière, Serge

    2017-09-01

    Elastomeric pumps can be useful for the administration of antibiotics in the outpatient setting. To determine amoxicillin degradation in elastomeric pumps, as well as the effectiveness of amoxicillin treatment administered by elastomeric pumps. Antibiotic degradation was measured in elastomeric pumps filled with 6 g of amoxicillin in 240 mL of NaCl 0.9% by drawing samples at 12 h intervals when stored in the fridge for 48 h and when worn around the waist for 24 h. Subsequently nine patients were treated with continuous infusions of 8 or 12 g of amoxicillin per day. Plasma amoxicillin concentrations were measured on each visit to the outpatient parenteral antibiotic therapy unit. Clinical outcome was verified 3 months after the end of treatment. Amoxicillin degradation in elastomeric pumps reached 10% after 48 h in the fridge and an additional 30% when worn around the waist for 24 h. Mean plasma drug concentrations achieved with 12 g of amoxicillin per day were 18.5 mg/L (95% CI 13.5-23.5), which is largely above the MIC of amoxicillin-susceptible bacteria. Nine patients treated for various complicated infections were cured and had no unexpected adverse effects. Adequate plasma drug concentrations and favourable clinical outcomes suggest that amoxicillin can be administered by continuous infusion using elastomeric pumps. This treatment modality does not fulfil formal requirements regarding pharmaceutical stability, but the resulting safety impact in patients is probably limited. Therapeutic drug monitoring and a close clinical follow-up are recommended if this route of administration is chosen. © The Author 2017. Published by Oxford University Press on behalf of the British Society for Antimicrobial Chemotherapy. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

  11. Spirulina does not decrease muscle damage nor oxdidative stress in cycling athletes with adequate nutritional status

    Directory of Open Access Journals (Sweden)

    G.A.M. Franca

    2010-12-01

    Full Text Available The objective of this study was to assess the effect of Spirulina maxima on oxidative stress and muscle damage in cycling athletes subjected to high volume and intensity of training. Eighteen male athletes were randomly divided into an experimental group (n=11 with age 27.8±3.5 and placebo (n=7 with age 34.3±2.3 in a double-blind fashion. They carried out a protocol of Spirulina dietary supplementation (7.5 g/day of placebo for four weeks and maintained their trainings during this period. A nutritional anamnesis was performed and blood tests were done to determine pre and post levels of creatine kinase (CK, lactic dehydrogenase (LHD, superoxide dismutase (SOD and malondialdehyde (MDA. The supplemented and placebo groups performed the same volume training, has adequate macronutrients and antioxidant vitamins ingestion before study, as well as initial CK, LDH, SOD and MDA levels. Supplementation did not promote a significant alteration in CK levels on supplemented group (158.4±16.3 for 140.0±16.6 U/l, p>0.05, LDH (420±13.2 for 394.9±27.9 UI/l, p>0.05, MDA (2.8±0.2 for 2.9±0.4 nmol/ml, p>0.05, nor an increase in the SOD (7.3±0.6 for 7.0±0.6 U/mg Hb, p>0.05. We conclude that administration of Spirulina does not interfere in the magnitude of muscle damage nor in antioxidant status of cycling athletes that practice intense training.

  12. Do Foley catheters adequately drain the bladder? Evidence from CT imaging studies

    Energy Technology Data Exchange (ETDEWEB)

    Avulova, Svetlana; Li, Valery J.; Khusid, Johnathan A. [Department of Urology, SUNY Downstate College of Medicine, Brooklyn, NY (United States); Choi, Woo S. [Radiology, SUNY Downstate College of Medicine, Brooklyn, NY (United States); Weiss, Jeffrey P., E-mail: johnathan.khusid@downstate.edu [Department of Urology, Weill Cornell Medical College, New York, NY (United States)

    2015-05-15

    Introduction: The Foley catheter has been widely assumed to be an effective means of draining the bladder. However, recent studies have brought into question its efficacy. The objective of our study is to further assess the adequacy of Foley catheter for complete drainage of the bladder. Materials and Methods: Consecutive catheterized patients were identified from a retrospective review of contrast enhanced and non-contrast enhanced computed tomographic (CT) abdomen and pelvis studies completed from 7/1/2011-6/30/2012. Residual urine volume (RUV) was measured using 5mm axial CT sections as follows: The length (L) and width (W) of the bladder in the section with the greatest cross sectional area was combined with bladder height (H) as determined by multiplanar reformatted images in order to calculate RUV by applying the formula for the volume (V) of a sphere in a cube:V=(π/6)⁎L⁎W⁎H). Results: RUVs of 167 (mean age 67) consecutively catheterized men (n=72) and women (n=95) identified by CT abdomen and pelvis studies were calculated. The mean RUV was 13.2 mL (range: 0.0 mL-859.1 mL, standard deviation: 75.9 mL, margin of error at 95% confidence:11.6 mL). Four (2.4%) catheterized patients had RUVs of >50 mL, two of whom had an improperly placed catheter tip noted on their CT-reports. Conclusions: Previous studies have shown that up to 43% of catheterized patients had a RUV greater than 50 mL, suggesting inadequacy of bladder drainage via the Foley catheter. Our study indicated that the vast majority of patients with Foley catheters (97.6%), had adequately drained bladders with volumes of <50 mL. (author)

  13. Emotional Experiences of Obese Women with Adequate Gestational Weight Variation: A Qualitative Study.

    Directory of Open Access Journals (Sweden)

    Débora Bicudo Faria-Schützer

    Full Text Available As a result of the growth of the obese population, the number of obese women of fertile age has increased in the last few years. Obesity in pregnancy is related to greater levels of anxiety, depression and physical harm. However, pregnancy is an opportune moment for the intervention of health care professionals to address obesity. The objective of this study was to describe how obese pregnant women emotionally experience success in adequate weight control.Using a qualitative design that seeks to understand content in the field of health, the sample of subjects was deliberated, with thirteen obese pregnant women selected to participate in an individual interview. Data was analysed by inductive content analysis and includes complete transcription of the interviews, re-readings using suspended attention, categorization in discussion topics and the qualitative and inductive analysis of the content. The analysis revealed four categories, three of which show the trajectory of body care that obese women experience during pregnancy: 1 The obese pregnant woman starts to think about her body;2 The challenge of the diet for the obese pregnant woman; 3 The relation of the obese pregnant woman with the team of antenatal professionals. The fourth category reveals the origin of the motivation for the change: 4 The potentializing factors for change: the motivation of the obese woman while pregnant.During pregnancy, obese women are more in touch with themselves and with their emotional conflicts. Through the transformations of their bodies, women can start a more refined self-care process and experience of the body-mind unit. The fear for their own and their baby's life, due to the risks posed by obesity, appears to be a great potentializing factor for change. The relationship with the professionals of the health care team plays an important role in the motivational support of the obese pregnant woman.

  14. Prevention of mother to child transmission lay counsellors: Are they adequately trained?

    Directory of Open Access Journals (Sweden)

    Catherine H. Thurling

    2012-05-01

    Full Text Available South Africa’s high prevalence of human immunodeficiency virus (HIV infected women requires a comprehensive health care approach to pregnancy because of the added risk of their HIV status. As a result of the shortage of health care workers in South Africa, lay counsellors play important roles in the prevention of mother to child transmission of HIV (PMTCT.There is no standardization of training of lay counsellors in South Africa, and training varies in length depending on the training organisation.The study aimed to investigate the training of lay counsellors by analysing their training curricula and interviewing lay counsellors about their perceptions of their training.A two phase research method was applied. Phase one documented an analysis of the training curricula. Phase two was semi-structured interviews with the participants. Purposive sampling was undertaken for this study. The total sample size was 13 people, with a final sample of 9 participants, determined at the point of data saturation.The research was qualitative, descriptive and contextual in design. The curricula analysed had different styles of delivery, and the approaches to learning and courses varied, resulting in inconsistent training outcomes. A need for supervision and mentorship in the working environment was also noted.The training of lay counsellors needs to be adapted to meet the extended roles that they are playing in PMTCT. The standardization of training programmes, and the incorporation of a system of mentorship in the work environment, would ensure that the lay counsellors are adequately prepared for their role in PMTCT.

  15. Adequate antigen availability: a key issue for novel approaches to tumor vaccination and tumor immunotherapy.

    Science.gov (United States)

    Accolla, Roberto S; Tosi, Giovanna

    2013-03-01

    A crucial parameter for activation of the anti-tumor immune response is an adequate antigen availability (AAA) defined here as the optimal tumor antigen dose and related antigen processing and MHC-II-restricted presentation necessary to efficiently trigger tumor-specific TH cells. We will discuss two distinct experimental systems: a) a preventive anti-tumor vaccination system; b) a therapy-induced anti-tumor vaccination approach. In the first case tumor cells are rendered constitutively MHC-II+ by transfecting them with the MHC-II transcriptional activator CIITA. Here AAA is generated by the function of tumor's newly expressed MHC-II molecules to present tumor-associated antigens to tumor-specific TH cells. In the second case, AAA is generated by treating established tumors with neovasculature-targeted TNFα. In conjuction with Melphalan, targeted TNFα delivery produces extensive areas of tumor necrosis that generate AAA capable of optimally activate tumor-specific TH cells which in turn activate CTL immune effectors. In both experimental systems tumor rejection and persistent and long-lived TH cell anti-tumor memory, responsible of defending the animals from subsequent challenges with tumor cells, are achieved. Based on these and other investigators' results we propose that AAA is a key element for triggering adaptive immune functions resulting in subversion from a pro-tumor to an anti-tumor microenvironment, tumor rejection and acquisition of anti-tumor immune memory. Hypotheses of neuro-immune networks involved in these approaches are discussed. These considerations are important also for the comprehension of how chemotherapy and/or radiation therapies may help to block and/or to eradicate the tumor and for the construction of suitable anti-tumor vaccine strategies.

  16. Emotional Experiences of Obese Women with Adequate Gestational Weight Variation: A Qualitative Study

    Science.gov (United States)

    Faria-Schützer, Débora Bicudo; Surita, Fernanda Garanhani de Castro; Alves, Vera Lucia Pereira; Vieira, Carla Maria; Turato, Egberto Ribeiro

    2015-01-01

    Background As a result of the growth of the obese population, the number of obese women of fertile age has increased in the last few years. Obesity in pregnancy is related to greater levels of anxiety, depression and physical harm. However, pregnancy is an opportune moment for the intervention of health care professionals to address obesity. The objective of this study was to describe how obese pregnant women emotionally experience success in adequate weight control. Methods and Findings Using a qualitative design that seeks to understand content in the field of health, the sample of subjects was deliberated, with thirteen obese pregnant women selected to participate in an individual interview. Data was analysed by inductive content analysis and includes complete transcription of the interviews, re-readings using suspended attention, categorization in discussion topics and the qualitative and inductive analysis of the content. The analysis revealed four categories, three of which show the trajectory of body care that obese women experience during pregnancy: 1) The obese pregnant woman starts to think about her body;2) The challenge of the diet for the obese pregnant woman; 3) The relation of the obese pregnant woman with the team of antenatal professionals. The fourth category reveals the origin of the motivation for the change: 4) The potentializing factors for change: the motivation of the obese woman while pregnant. Conclusions During pregnancy, obese women are more in touch with themselves and with their emotional conflicts. Through the transformations of their bodies, women can start a more refined self-care process and experience of the body-mind unit. The fear for their own and their baby's life, due to the risks posed by obesity, appears to be a great potentializing factor for change. The relationship with the professionals of the health care team plays an important role in the motivational support of the obese pregnant woman. PMID:26529600

  17. Capillary PO2 does not adequately reflect arterial PO2 in hypoxemic COPD patients.

    Science.gov (United States)

    Magnet, Friederike Sophie; Majorski, Daniel Sebastian; Callegari, Jens; Schwarz, Sarah Bettina; Schmoor, Claudia; Windisch, Wolfram; Storre, Jan Hendrik

    2017-01-01

    To compare arterial (P a O 2 ) with capillary (P c O 2 ) partial pressure of oxygen in hypoxemic COPD patients because capillary blood gas analysis (CBG) is increasingly being used as an alternative to arterial blood gas analysis (ABG) in a non-intensive care unit setting, although the agreement between P c O 2 and P a O 2 has not been evaluated in hypoxemic COPD patients. Bland-Altman comparison of P a O 2 and P c O 2 served as the primary outcome parameter if P c O 2 values were ≤60 mmHg and the secondary outcome parameter if P c O 2 values were ≤55 mmHg. Pain associated with the measurements was assessed using a 100-mm visual analog scale. One hundred and two P a O 2 /P c O 2 measurement pairs were obtained. For P c O 2 values ≤60 mmHg, the mean difference between P a O 2 and P c O 2 was 5.99±6.05 mmHg (limits of agreement: -5.88 to 17.85 mmHg). For P c O 2 values ≤55 mmHg (n=73), the mean difference was 5.33±5.52 mmHg (limits of agreement: -5.48 to 16.15 mmHg). If P a O 2 ≤55 (≤60) mmHg was set as the cut-off value, in 20.6% (30.4%) of all patients, long-term oxygen therapy have been unnecessarily prescribed if only P c O 2 would have been assessed. ABG was rated as more painful compared with CBG. P c O 2 does not adequately reflect P a O 2 in hypoxemic COPD patients, which can lead to a relevant number of unnecessary long-term oxygen therapy prescriptions.

  18. Does phenomenological kinetics provide an adequate description of heterogeneous catalytic reactions?

    Science.gov (United States)

    Temel, Burcin; Meskine, Hakim; Reuter, Karsten; Scheffler, Matthias; Metiu, Horia

    2007-05-01

    Phenomenological kinetics (PK) is widely used in the study of the reaction rates in heterogeneous catalysis, and it is an important aid in reactor design. PK makes simplifying assumptions: It neglects the role of fluctuations, assumes that there is no correlation between the locations of the reactants on the surface, and considers the reacting mixture to be an ideal solution. In this article we test to what extent these assumptions damage the theory. In practice the PK rate equations are used by adjusting the rate constants to fit the results of the experiments. However, there are numerous examples where a mechanism fitted the data and was shown later to be erroneous or where two mutually exclusive mechanisms fitted well the same set of data. Because of this, we compare the PK equations to "computer experiments" that use kinetic Monte Carlo (kMC) simulations. Unlike in real experiments, in kMC the structure of the surface, the reaction mechanism, and the rate constants are known. Therefore, any discrepancy between PK and kMC must be attributed to an intrinsic failure of PK. We find that the results obtained by solving the PK equations and those obtained from kMC, while using the same rate constants and the same reactions, do not agree. Moreover, when we vary the rate constants in the PK model to fit the turnover frequencies produced by kMC, we find that the fit is not adequate and that the rate constants that give the best fit are very different from the rate constants used in kMC. The discrepancy between PK and kMC for the model of CO oxidation used here is surprising since the kMC model contains no lateral interactions that would make the coverage of the reactants spatially inhomogeneous. Nevertheless, such inhomogeneities are created by the interplay between the rate of adsorption, of desorption, and of vacancy creation by the chemical reactions.

  19. Importance of adequately performed Valsalva maneuver to detect patent foramen ovale during transesophageal echocardiography.

    Science.gov (United States)

    Rodrigues, Ana Clara; Picard, Michael H; Carbone, Aime; Arruda, Ana Lúcia; Flores, Thaís; Klohn, Juliana; Furtado, Meive; Lira-Filho, Edgar B; Cerri, Giovanni G; Andrade, José L

    2013-11-01

    Transesophageal echocardiography (TEE) plays an important role in evaluating cardioembolic sources of emboli. The identification of a patent foramen ovale (PFO) is reportedly improved with TEE compared with transthoracic echocardiography (TTE), but the Valsalva maneuver during TEE may be difficult or suboptimal. The aim of this study was to assess the efficacy of the Valsalva maneuver for PFO diagnosis using TEE compared with TTE by evaluating patients with ischemic stroke referred for echocardiography. Only patients able to perform the Valsalva maneuver during TTE were included; efficacy was defined by a 20 cm/sec decrease in transmitral E velocity. A PFO was judged present when microbubbles of agitated intravenous saline were seen in the left chambers within three cycles after right atrial opacification. Of 108 patients (mean age, 55 ± 15 years; 61 men), 48 (44%) were judged to have PFOs by TEE and/or TTE. In 36 patients (33% of the total, 75% of those with PFOs), microbubbles were observed both by TEE and TTE, in seven patients only during TTE, and in five patients only during TEE. In patients able to satisfactorily perform the Valsalva maneuver during TEE, 22 PFOs were found, and two shunts (9%) were missed, whereas in patients unable to perform this maneuver, 26 PFOs were observed, with five shunts missed (19%) (P TTE, either the echocardiographic window was suboptimal or the shunt was small. An adequate Valsalva maneuver is crucial for diagnosis of PFO; most patients with stroke may be screened using TTE with contrast and the Valsalva maneuver, with TEE indicated in case of suboptimal transthoracic images. Copyright © 2013 American Society of Echocardiography. Published by Mosby, Inc. All rights reserved.

  20. Robust Sequential Analysis for Special Capacities

    OpenAIRE

    高橋, 一

    1985-01-01

    Huber type robustness will be considered for some extensions of Wald's Sequential Probability Ratio Test, including Wald's three decision problem and the Kiefer-Weiss formulation. The results of Huber (1965, 1968), Huber and Strassen (1973), Rieder (1977) and Osterreicher (1978) will be extended to derive a least favorable tuple in the multiple decision problem. And then the asymptotically least favorable KieferWeiss procedure together with its asymptotic relative efficiency for the s-contami...

  1. Muscle Synergy-Driven Robust Motion Control.

    Science.gov (United States)

    Min, Kyuengbo; Iwamoto, Masami; Kakei, Shinji; Kimpara, Hideyuki

    2018-04-01

    Humans are able to robustly maintain desired motion and posture under dynamically changing circumstances, including novel conditions. To accomplish this, the brain needs to optimize the synergistic control between muscles against external dynamic factors. However, previous related studies have usually simplified the control of multiple muscles using two opposing muscles, which are minimum actuators to simulate linear feedback control. As a result, they have been unable to analyze how muscle synergy contributes to motion control robustness in a biological system. To address this issue, we considered a new muscle synergy concept used to optimize the synergy between muscle units against external dynamic conditions, including novel conditions. We propose that two main muscle control policies synergistically control muscle units to maintain the desired motion against external dynamic conditions. Our assumption is based on biological evidence regarding the control of multiple muscles via the corticospinal tract. One of the policies is the group control policy (GCP), which is used to control muscle group units classified based on functional similarities in joint control. This policy is used to effectively resist external dynamic circumstances, such as disturbances. The individual control policy (ICP) assists the GCP in precisely controlling motion by controlling individual muscle units. To validate this hypothesis, we simulated the reinforcement of the synergistic actions of the two control policies during the reinforcement learning of feedback motion control. Using this learning paradigm, the two control policies were synergistically combined to result in robust feedback control under novel transient and sustained disturbances that did not involve learning. Further, by comparing our data to experimental data generated by human subjects under the same conditions as those of the simulation, we showed that the proposed synergy concept may be used to analyze muscle synergy

  2. Automatic Mode Transition Enabled Robust Triboelectric Nanogenerators.

    Science.gov (United States)

    Chen, Jun; Yang, Jin; Guo, Hengyu; Li, Zhaoling; Zheng, Li; Su, Yuanjie; Wen, Zhen; Fan, Xing; Wang, Zhong Lin

    2015-12-22

    Although the triboelectric nanogenerator (TENG) has been proven to be a renewable and effective route for ambient energy harvesting, its robustness remains a great challenge due to the requirement of surface friction for a decent output, especially for the in-plane sliding mode TENG. Here, we present a rationally designed TENG for achieving a high output performance without compromising the device robustness by, first, converting the in-plane sliding electrification into a contact separation working mode and, second, creating an automatic transition between a contact working state and a noncontact working state. The magnet-assisted automatic transition triboelectric nanogenerator (AT-TENG) was demonstrated to effectively harness various ambient rotational motions to generate electricity with greatly improved device robustness. At a wind speed of 6.5 m/s or a water flow rate of 5.5 L/min, the harvested energy was capable of lighting up 24 spot lights (0.6 W each) simultaneously and charging a capacitor to greater than 120 V in 60 s. Furthermore, due to the rational structural design and unique output characteristics, the AT-TENG was not only capable of harvesting energy from natural bicycling and car motion but also acting as a self-powered speedometer with ultrahigh accuracy. Given such features as structural simplicity, easy fabrication, low cost, wide applicability even in a harsh environment, and high output performance with superior device robustness, the AT-TENG renders an effective and practical approach for ambient mechanical energy harvesting as well as self-powered active sensing.

  3. Is CBA ranking of transport investments robust?

    OpenAIRE

    Börjesson, Maria; Eliasson, Jonas; Lundberg, Mattias

    2012-01-01

    Cost-benefit analysis (CBA) is often used when many transport investments need to be ranked against each other, for example in national investment planning. However, results are often questioned on claims that the ranking depends crucially on uncertain assumptions about the future, and on methodologically or ethically contestable trade-offs of different types of benefits relative to each other. This paper explores the robustness of CBA rankings of transport investments with respect to two typ...

  4. Frozen robust multiarray analysis (fRMA)

    OpenAIRE

    McCall, Matthew N.; Bolstad, Benjamin M.; Irizarry, Rafael A.

    2010-01-01

    Robust multiarray analysis (RMA) is the most widely used preprocessing algorithm for Affymetrix and Nimblegen gene expression microarrays. RMA performs background correction, normalization, and summarization in a modular way. The last 2 steps require multiple arrays to be analyzed simultaneously. The ability to borrow information across samples provides RMA various advantages. For example, the summarization step fits a parametric model that accounts for probe effects, assumed to be fixed acro...

  5. Robust inversion via semistochastic dimensionality reduction

    OpenAIRE

    Aravkin, Aleksandr; Friedlander, Michael P.; van Leeuwen, Tristan

    2011-01-01

    We consider a class of inverse problems where it is possible to aggregate the results of multiple experiments. This class includes problems where the forward model is the solution operator to linear ODEs or PDEs. The tremendous size of such problems motivates dimensionality reduction techniques based on randomly mixing experiments. These techniques break down, however, when robust data-fitting formulations are used, which are essential in cases of missing data, unusually large errors, and sys...

  6. Heteroscedasticity resistant robust covariance matrix estimator

    Czech Academy of Sciences Publication Activity Database

    Víšek, Jan Ámos

    2010-01-01

    Roč. 17, č. 27 (2010), s. 33-49 ISSN 1212-074X Grant - others:GA UK(CZ) GA402/09/0557 Institutional research plan: CEZ:AV0Z10750506 Keywords : Regression * Covariance matrix * Heteroscedasticity * Resistant Subject RIV: BB - Applied Statistics, Operational Research http://library.utia.cas.cz/separaty/2011/SI/visek-heteroscedasticity resistant robust covariance matrix estimator.pdf

  7. Robust topology design of periodic grating surfaces

    DEFF Research Database (Denmark)

    Friis, Kasper Storgaard; Sigmund, Ole

    2012-01-01

    Modern nanoscale manufacturing techniques allow for a high degree of flexibility in designing surface microstructures and nanostructures. Injection molding of nanosized features allows for mass production of plastic components with a tailored nanostructure producing specific optical effects...... depending on the purpose. This work details the use of topology optimization for designing periodic polymer grating surfaces with complex optical properties. A method based on robust topology optimization is formulated for designing the nanostructure of plastic surfaces with extreme reflection...

  8. A Robust Control Framework for Malware Filtering

    OpenAIRE

    Bloem, Michael; Alpcan, Tansu; Basar, Tamer

    2009-01-01

    We study and develop a robust control framework for malware filtering and network security. We investigate the malware filtering problem by capturing the tradeoff between increased security on one hand and continued usability of the network on the other. We analyze the problem using a linear control system model with a quadratic cost structure and develop algorithms based on H infinity-optimal control theory. A dynamic feedback filter is derived and shown via numerical analysis to be an impro...

  9. Efficient CEPSTRAL Normalization for Robust Speech Recognition

    Science.gov (United States)

    1993-01-01

    CMN curve depends on the duration of the utterance, and is plotted in Figure 2 for the average duration in the DARPA Wall Street Journal task, 7...task consisting of dictation of sentences from the Wall Street Journal . A component of that evaluation involved utterances from a set of unknown... Wall Street Journal domain. 73 The version of SPHINX-II used for this evaluation was con- figured to maximize the robustness of the recognition pro

  10. Matlab as a robust control design tool

    Science.gov (United States)

    Gregory, Irene M.

    1994-01-01

    This presentation introduces Matlab as a tool used in flight control research. The example used to illustrate some of the capabilities of this software is a robust controller designed for a single stage to orbit air breathing vehicles's ascent to orbit. The global requirements of the controller are to stabilize the vehicle and follow a trajectory in the presence of atmospheric disturbances and strong dynamic coupling between airframe and propulsion.

  11. Robust Decision Making for Improved Mission Assurance

    Science.gov (United States)

    2014-06-01

    Computer Science, Computer Engineering, and Applied Computing ( GEM 󈧑 & ICAI󈧑). A detailed description of a RML model/agent capable of employing...Democratic Republic of Congo. A D-optimal design of experiments enables identification of a robust national policy. Employment of a multi-attribute utility...ed) Handbook of Computational Approaches to Counterterrorism. Springer, New York, pages 363-399. [24] Schvaneveldt, R.W. (1990). Pathfinder

  12. TAO-robust backpropagation learning algorithm.

    Science.gov (United States)

    Pernía-Espinoza, Alpha V; Ordieres-Meré, Joaquín B; Martínez-de-Pisón, Francisco J; González-Marcos, Ana

    2005-03-01

    In several fields, as industrial modelling, multilayer feedforward neural networks are often used as universal function approximations. These supervised neural networks are commonly trained by a traditional backpropagation learning format, which minimises the mean squared error (mse) of the training data. However, in the presence of corrupted data (outliers) this training scheme may produce wrong models. We combine the benefits of the non-linear regression model tau-estimates [introduced by Tabatabai, M. A. Argyros, I. K. Robust Estimation and testing for general nonlinear regression models. Applied Mathematics and Computation. 58 (1993) 85-101] with the backpropagation algorithm to produce the TAO-robust learning algorithm, in order to deal with the problems of modelling with outliers. The cost function of this approach has a bounded influence function given by the weighted average of two psi functions, one corresponding to a very robust estimate and the other to a highly efficient estimate. The advantages of the proposed algorithm are studied with an example.

  13. Distributed redundancy and robustness in complex systems

    KAUST Repository

    Randles, Martin

    2011-03-01

    The uptake and increasing prevalence of Web 2.0 applications, promoting new large-scale and complex systems such as Cloud computing and the emerging Internet of Services/Things, requires tools and techniques to analyse and model methods to ensure the robustness of these new systems. This paper reports on assessing and improving complex system resilience using distributed redundancy, termed degeneracy in biological systems, to endow large-scale complicated computer systems with the same robustness that emerges in complex biological and natural systems. However, in order to promote an evolutionary approach, through emergent self-organisation, it is necessary to specify the systems in an \\'open-ended\\' manner where not all states of the system are prescribed at design-time. In particular an observer system is used to select robust topologies, within system components, based on a measurement of the first non-zero Eigen value in the Laplacian spectrum of the components\\' network graphs; also known as the algebraic connectivity. It is shown, through experimentation on a simulation, that increasing the average algebraic connectivity across the components, in a network, leads to an increase in the variety of individual components termed distributed redundancy; the capacity for structurally distinct components to perform an identical function in a particular context. The results are applied to a specific application where active clustering of like services is used to aid load balancing in a highly distributed network. Using the described procedure is shown to improve performance and distribute redundancy. © 2010 Elsevier Inc.

  14. Sparse alignment for robust tensor learning.

    Science.gov (United States)

    Lai, Zhihui; Wong, Wai Keung; Xu, Yong; Zhao, Cairong; Sun, Mingming

    2014-10-01

    Multilinear/tensor extensions of manifold learning based algorithms have been widely used in computer vision and pattern recognition. This paper first provides a systematic analysis of the multilinear extensions for the most popular methods by using alignment techniques, thereby obtaining a general tensor alignment framework. From this framework, it is easy to show that the manifold learning based tensor learning methods are intrinsically different from the alignment techniques. Based on the alignment framework, a robust tensor learning method called sparse tensor alignment (STA) is then proposed for unsupervised tensor feature extraction. Different from the existing tensor learning methods, L1- and L2-norms are introduced to enhance the robustness in the alignment step of the STA. The advantage of the proposed technique is that the difficulty in selecting the size of the local neighborhood can be avoided in the manifold learning based tensor feature extraction algorithms. Although STA is an unsupervised learning method, the sparsity encodes the discriminative information in the alignment step and provides the robustness of STA. Extensive experiments on the well-known image databases as well as action and hand gesture databases by encoding object images as tensors demonstrate that the proposed STA algorithm gives the most competitive performance when compared with the tensor-based unsupervised learning methods.

  15. Interlinked bistable mechanisms generate robust mitotic transitions.

    Science.gov (United States)

    Hutter, Lukas H; Rata, Scott; Hochegger, Helfrid; Novák, Béla

    2017-10-18

    The transitions between phases of the cell cycle have evolved to be robust and switch-like, which ensures temporal separation of DNA replication, sister chromatid separation, and cell division. Mathematical models describing the biochemical interaction networks of cell cycle regulators attribute these properties to underlying bistable switches, which inherently generate robust, switch-like, and irreversible transitions between states. We have recently presented new mathematical models for two control systems that regulate crucial transitions in the cell cycle: mitotic entry and exit, 1 and the mitotic checkpoint. 2 Each of the two control systems is characterized by two interlinked bistable switches. In the case of mitotic checkpoint control, these switches are mutually activating, whereas in the case of the mitotic entry/exit network, the switches are mutually inhibiting. In this Perspective we describe the qualitative features of these regulatory motifs and show that having two interlinked bistable mechanisms further enhances robustness and irreversibility. We speculate that these network motifs also underlie other cell cycle transitions and cellular transitions between distinct biochemical states.

  16. A robust nonlinear filter for image restoration.

    Science.gov (United States)

    Koivunen, V

    1995-01-01

    A class of nonlinear regression filters based on robust estimation theory is introduced. The goal of the filtering is to recover a high-quality image from degraded observations. Models for desired image structures and contaminating processes are employed, but deviations from strict assumptions are allowed since the assumptions on signal and noise are typically only approximately true. The robustness of filters is usually addressed only in a distributional sense, i.e., the actual error distribution deviates from the nominal one. In this paper, the robustness is considered in a broad sense since the outliers may also be due to inappropriate signal model, or there may be more than one statistical population present in the processing window, causing biased estimates. Two filtering algorithms minimizing a least trimmed squares criterion are provided. The design of the filters is simple since no scale parameters or context-dependent threshold values are required. Experimental results using both real and simulated data are presented. The filters effectively attenuate both impulsive and nonimpulsive noise while recovering the signal structure and preserving interesting details.

  17. Mutational robustness of gene regulatory networks.

    Directory of Open Access Journals (Sweden)

    Aalt D J van Dijk

    Full Text Available Mutational robustness of gene regulatory networks refers to their ability to generate constant biological output upon mutations that change network structure. Such networks contain regulatory interactions (transcription factor-target gene interactions but often also protein-protein interactions between transcription factors. Using computational modeling, we study factors that influence robustness and we infer several network properties governing it. These include the type of mutation, i.e. whether a regulatory interaction or a protein-protein interaction is mutated, and in the case of mutation of a regulatory interaction, the sign of the interaction (activating vs. repressive. In addition, we analyze the effect of combinations of mutations and we compare networks containing monomeric with those containing dimeric transcription factors. Our results are consistent with available data on biological networks, for example based on evolutionary conservation of network features. As a novel and remarkable property, we predict that networks are more robust against mutations in monomer than in dimer transcription factors, a prediction for which analysis of conservation of DNA binding residues in monomeric vs. dimeric transcription factors provides indirect evidence.

  18. UNIX-based operating systems robustness evaluation

    Science.gov (United States)

    Chang, Yu-Ming

    1996-01-01

    Robust operating systems are required for reliable computing. Techniques for robustness evaluation of operating systems not only enhance the understanding of the reliability of computer systems, but also provide valuable feed- back to system designers. This thesis presents results from robustness evaluation experiments on five UNIX-based operating systems, which include Digital Equipment's OSF/l, Hewlett Packard's HP-UX, Sun Microsystems' Solaris and SunOS, and Silicon Graphics' IRIX. Three sets of experiments were performed. The methodology for evaluation tested (1) the exception handling mechanism, (2) system resource management, and (3) system capacity under high workload stress. An exception generator was used to evaluate the exception handling mechanism of the operating systems. Results included exit status of the exception generator and the system state. Resource management techniques used by individual operating systems were tested using programs designed to usurp system resources such as physical memory and process slots. Finally, the workload stress testing evaluated the effect of the workload on system performance by running a synthetic workload and recording the response time of local and remote user requests. Moderate to severe performance degradations were observed on the systems under stress.

  19. Engineering Robustness of Microbial Cell Factories.

    Science.gov (United States)

    Gong, Zhiwei; Nielsen, Jens; Zhou, Yongjin J

    2017-10-01

    Metabolic engineering and synthetic biology offer great prospects in developing microbial cell factories capable of converting renewable feedstocks into fuels, chemicals, food ingredients, and pharmaceuticals. However, prohibitively low production rate and mass concentration remain the major hurdles in industrial processes even though the biosynthetic pathways are comprehensively optimized. These limitations are caused by a variety of factors unamenable for host cell survival, such as harsh industrial conditions, fermentation inhibitors from biomass hydrolysates, and toxic compounds including metabolic intermediates and valuable target products. Therefore, engineered microbes with robust phenotypes is essential for achieving higher yield and productivity. In this review, the recent advances in engineering robustness and tolerance of cell factories is described to cope with these issues and briefly introduce novel strategies with great potential to enhance the robustness of cell factories, including metabolic pathway balancing, transporter engineering, and adaptive laboratory evolution. This review also highlights the integration of advanced systems and synthetic biology principles toward engineering the harmony of overall cell function, more than the specific pathways or enzymes. © 2017 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  20. Robust Discriminant Regression for Feature Extraction.

    Science.gov (United States)

    Lai, Zhihui; Mo, Dongmei; Wong, Wai Keung; Xu, Yong; Miao, Duoqian; Zhang, David

    2017-10-09

    Ridge regression (RR) and its extended versions are widely used as an effective feature extraction method in pattern recognition. However, the RR-based methods are sensitive to the variations of data and can learn only limited number of projections for feature extraction and recognition. To address these problems, we propose a new method called robust discriminant regression (RDR) for feature extraction. In order to enhance the robustness, the L₂,₁-norm is used as the basic metric in the proposed RDR. The designed robust objective function in regression form can be solved by an iterative algorithm containing an eigenfunction, through which the optimal orthogonal projections of RDR can be obtained by eigen decomposition. The convergence analysis and computational complexity are presented. In addition, we also explore the intrinsic connections and differences between the RDR and some previous methods. Experiments on some well-known databases show that RDR is superior to the classical and very recent proposed methods reported in the literature, no matter the L₂-norm or the L₂,₁-norm-based regression methods. The code of this paper can be downloaded from http://www.scholat.com/laizhihui.

  1. Robustness of inflation to inhomogeneous initial conditions

    Energy Technology Data Exchange (ETDEWEB)

    Clough, Katy; Lim, Eugene A. [Theoretical Particle Physics and Cosmology Group, Physics Department, Kings College London, Strand, London WC2R 2LS (United Kingdom); DiNunno, Brandon S.; Fischler, Willy; Flauger, Raphael; Paban, Sonia, E-mail: katy.clough@kcl.ac.uk, E-mail: eugene.a.lim@gmail.com, E-mail: bsd86@physics.utexas.edu, E-mail: fischler@physics.utexas.edu, E-mail: flauger@physics.utexas.edu, E-mail: paban@physics.utexas.edu [Department of Physics, The University of Texas at Austin, Austin, TX, 78712 (United States)

    2017-09-01

    We consider the effects of inhomogeneous initial conditions in both the scalar field profile and the extrinsic curvature on different inflationary models. In particular, we compare the robustness of small field inflation to that of large field inflation, using numerical simulations with Einstein gravity in 3+1 dimensions. We find that small field inflation can fail in the presence of subdominant gradient energies, suggesting that it is much less robust to inhomogeneities than large field inflation, which withstands dominant gradient energies. However, we also show that small field inflation can be successful even if some regions of spacetime start out in the region of the potential that does not support inflation. In the large field case, we confirm previous results that inflation is robust if the inflaton occupies the inflationary part of the potential. Furthermore, we show that increasing initial scalar gradients will not form sufficiently massive inflation-ending black holes if the initial hypersurface is approximately flat. Finally, we consider the large field case with a varying extrinsic curvature K , such that some regions are initially collapsing. We find that this may again lead to local black holes, but overall the spacetime remains inflationary if the spacetime is open, which confirms previous theoretical studies.

  2. Robustness of airline alliance route networks

    Science.gov (United States)

    Lordan, Oriol; Sallan, Jose M.; Simo, Pep; Gonzalez-Prieto, David

    2015-05-01

    The aim of this study is to analyze the robustness of the three major airline alliances' (i.e., Star Alliance, oneworld and SkyTeam) route networks. Firstly, the normalization of a multi-scale measure of vulnerability is proposed in order to perform the analysis in networks with different sizes, i.e., number of nodes. An alternative node selection criterion is also proposed in order to study robustness and vulnerability of such complex networks, based on network efficiency. And lastly, a new procedure - the inverted adaptive strategy - is presented to sort the nodes in order to anticipate network breakdown. Finally, the robustness of the three alliance networks are analyzed with (1) a normalized multi-scale measure of vulnerability, (2) an adaptive strategy based on four different criteria and (3) an inverted adaptive strategy based on the efficiency criterion. The results show that Star Alliance has the most resilient route network, followed by SkyTeam and then oneworld. It was also shown that the inverted adaptive strategy based on the efficiency criterion - inverted efficiency - shows a great success in quickly breaking networks similar to that found with betweenness criterion but with even better results.

  3. Tension and robustness in multitasking cellular networks.

    Directory of Open Access Journals (Sweden)

    Jeffrey V Wong

    Full Text Available Cellular networks multitask by exhibiting distinct, context-dependent dynamics. However, network states (parameters that generate a particular dynamic are often sub-optimal for others, defining a source of "tension" between them. Though multitasking is pervasive, it is not clear where tension arises, what consequences it has, and how it is resolved. We developed a generic computational framework to examine the source and consequences of tension between pairs of dynamics exhibited by the well-studied RB-E2F switch regulating cell cycle entry. We found that tension arose from task-dependent shifts in parameters associated with network modules. Although parameter sets common to distinct dynamics did exist, tension reduced both their accessibility and resilience to perturbation, indicating a trade-off between "one-size-fits-all" solutions and robustness. With high tension, robustness can be preserved by dynamic shifting of modules, enabling the network to toggle between tasks, and by increasing network complexity, in this case by gene duplication. We propose that tension is a general constraint on the architecture and operation of multitasking biological networks. To this end, our work provides a framework to quantify the extent of tension between any network dynamics and how it affects network robustness. Such analysis would suggest new ways to interfere with network elements to elucidate the design principles of cellular networks.

  4. Robust Subspace Clustering With Complex Noise.

    Science.gov (United States)

    He, Ran; Zhang, Yingya; Sun, Zhenan; Yin, Qiyue

    2015-11-01

    Subspace clustering has important and wide applications in computer vision and pattern recognition. It is a challenging task to learn low-dimensional subspace structures due to complex noise existing in high-dimensional data. Complex noise has much more complex statistical structures, and is neither Gaussian nor Laplacian noise. Recent subspace clustering methods usually assume a sparse representation of the errors incurred by noise and correct these errors iteratively. However, large corruptions incurred by complex noise cannot be well addressed by these methods. A novel optimization model for robust subspace clustering is proposed in this paper. Its objective function mainly includes two parts. The first part aims to achieve a sparse representation of each high-dimensional data point with other data points. The second part aims to maximize the correntropy between a given data point and its low-dimensional representation with other points. Correntropy is a robust measure so that the influence of large corruptions on subspace clustering can be greatly suppressed. An extension of pairwise link constraints is also proposed as prior information to deal with complex noise. Half-quadratic minimization is provided as an efficient solution to the proposed robust subspace clustering formulations. Experimental results on three commonly used data sets show that our method outperforms state-of-the-art subspace clustering methods.

  5. Neonatal bloodstream infections in a Ghanaian Tertiary Hospital: Are the current antibiotic recommendations adequate?

    Directory of Open Access Journals (Sweden)

    Appiah-Korang Labi

    2016-10-01

    Full Text Available Abstract Background Diagnosis of bloodstream infections (BSI in neonates is usually difficult due to minimal symptoms at presentation; thus early empirical therapy guided by local antibiotic susceptibility profile is necessary to improve therapeutic outcomes. Methods A review of neonatal blood cultures submitted to the microbiology department of the Korle-Bu Teaching Hospital was conducted from January 2010 through December 2013. We assessed the prevalence of bacteria and fungi involved in BSI and the susceptibility coverage of recommended empiric antibiotics by Ghana Standard Treatment guidelines and the WHO recommendations for managing neonatal sepsis. The national and WHO treatment guidelines recommend either ampicillin plus gentamicin or ampicillin plus cefotaxime for empiric treatment of neonatal BSI. The WHO recommendations also include cloxacillin plus gentamicin. We described the resistance profile over a 28-day neonatal period using multivariable logistic regression analysis with linear or restricted cubic splines. Results A total of 8,025 neonatal blood culture reports were reviewed over the four-year period. Total blood culture positivity was 21.9 %. Gram positive organisms accounted for most positive cultures, with coagulase negative staphylococci (CoNS being the most frequently isolated pathogen in early onset infections (EOS (59.1 % and late onset infections (LOS (52.8 %. Susceptibility coverage of early onset bacterial isolates were 20.7 % to ampicillin plus cefotaxime, 32.2 % to the combination of ampicillin and gentamicin, and 71.7 % to cloxacillin plus gentamicin. For LOS, coverage was 24.6 % to ampicillin plus cefotaxime, 36.2 % to the combination ampicillin and gentamicin and 63.6 % to cloxacillin plus gentamicin. Cloxacillin plus gentamicin remained the most active regimen for EOS and LOS after exclusion of BSI caused by CoNS. For this regimen, the adjusted odds of resistance decreased between 12-34 % per day from

  6. Global Uranium And Thorium Resources: Are They Adequate To Satisfy Demand Over The Next Half Century?

    Science.gov (United States)

    Lambert, I. B.

    2012-04-01

    This presentation will consider the adequacy of global uranium and thorium resources to meet realistic nuclear power demand scenarios over the next half century. It is presented on behalf of, and based on evaluations by, the Uranium Group - a joint initiative of the OECD Nuclear Energy Agency and the International Atomic Energy Agency, of which the author is a Vice Chair. The Uranium Group produces a biennial report on Uranium Resources, Production and Demand based on information from some 40 countries involved in the nuclear fuel cycle, which also briefly reviews thorium resources. Uranium: In 2008, world production of uranium amounted to almost 44,000 tonnes (tU). This supplied approximately three-quarters of world reactor requirements (approx. 59,000 tU), the remainder being met by previously mined uranium (so-called secondary sources). Information on availability of secondary sources - which include uranium from excess inventories, dismantling nuclear warheads, tails and spent fuel reprocessing - is incomplete, but such sources are expected to decrease in market importance after 2013. In 2008, the total world Reasonably Assured plus Inferred Resources of uranium (recoverable at less than 130/kgU) amounted to 5.4 million tonnes. In addition, it is clear that there are vast amounts of uranium recoverable at higher costs in known deposits, plus many as yet undiscovered deposits. The Uranium Group has concluded that the uranium resource base is more than adequate to meet projected high-case requirements for nuclear power for at least half a century. This conclusion does not assume increasing replacement of uranium by fuels from reprocessing current reactor wastes, or by thorium, nor greater reactor efficiencies, which are likely to ameliorate future uranium demand. However, progressively increasing quantities of uranium will need to be mined, against a backdrop of the relatively small number of producing facilities around the world, geopolitical uncertainties and

  7. Are parents in the UK equipped to provide adequate burns first aid?

    Science.gov (United States)

    Graham, Hamish E; Bache, Sarah E; Muthayya, Preetha; Baker, Julie; Ralston, David R

    2012-05-01

    Simple first aid following a burn injury has been shown to improve outcome. With this in mind, a prospective study was conducted to evaluate the knowledge of burns first aid amongst parents in South Yorkshire, United Kingdom. This information was used to identify which aspects of burn first aid need to be highlighted in an education campaign and who the target audience should be. A simple mnemonic is suggested to assist parental education on the topic. Parents attending outpatient clinics at Sheffield Children's Hospital were interviewed and asked about the first aid they would provide for a child with a large scald. Removal of hot clothes and jewellery; application of cold water for 10-20 min; obtaining medical advice; and covering the burn with a plastic film or clean cloth were all considered to be ideal responses. Variations in responses in relation to the age and ethnicity of the parent were noted. One hundred and eighty eight parents were included in the questionnaire. Of these, 81% (n=152) were white British and 20% (n=36) were from other ethnic groups. Only 10% (n=18) of all respondent would give all the ideal first aid steps. Less than 40% (n=73) of parents questioned would remove hot clothes and jewellery. There was no significant difference in responses between ethnic groups when assessing knowledge of the need to remove hot soaked clothing. Although 73% (n=137) of parents would run the burn under cool water, only 35% (n=66) would cool the burn for an adequate length of time. White British parents were significantly more likely to run cool water over the burn, and to continue this for the recommended 10-20 min. Whilst 88% (n=165) of parents would seek medical attention, this was significantly less in parents under 20 years old. Finally, 92% (n=173) of parents would protect the wound with appropriate dressings, but of note, 26% (n=9) of parents from minority ethnic groups would potentially impair burn healing by using inappropriate dressings and topical

  8. Adequate formal language performance in unilateral cochlear implanted children: is it indicative of complete recovery in all linguistic domains? Insights from referential communication.

    Science.gov (United States)

    Mancini, Patrizia; Dincer D'Alessandro, Hilal; Guerzoni, Letizia; Cuda, Domenico; Ruoppolo, Giovanni; Musacchio, Angela; Di Mario, Alessia; De Seta, Elio; Bosco, Ersilia; Nicastri, Maria

    2015-04-01

    Referential communication (RC) is a key element in achieving a successful communication. This case series aimed to evaluate RC in children with unilateral cochlear implants (CIs) with formal language skills within the normal range. A total of 31 children with CIs, with language development within the normal range, were assessed using the Pragmatic Language Skills test (MEDEA). Of the children with CIs, 83.9% reached performance levels appropriate for their chronological ages. The results confirmed a positive effect of cochlear implantation on RC development, although difficulties remained in some CI users. The outcomes emphasize the need to pay greater attention to the pragmatic aspects of language, assessing them with adequate testing in the early phase after cochlear implantation. Clear knowledge of children's communicative competence is the key in optimizing their communicative environments in order to create the basis for future successful interpersonal exchanges and social integration. Copyright © 2015 Elsevier Ireland Ltd. All rights reserved.

  9. Robust estimation of hydrological model parameters

    Directory of Open Access Journals (Sweden)

    A. Bárdossy

    2008-11-01

    Full Text Available The estimation of hydrological model parameters is a challenging task. With increasing capacity of computational power several complex optimization algorithms have emerged, but none of the algorithms gives a unique and very best parameter vector. The parameters of fitted hydrological models depend upon the input data. The quality of input data cannot be assured as there may be measurement errors for both input and state variables. In this study a methodology has been developed to find a set of robust parameter vectors for a hydrological model. To see the effect of observational error on parameters, stochastically generated synthetic measurement errors were applied to observed discharge and temperature data. With this modified data, the model was calibrated and the effect of measurement errors on parameters was analysed. It was found that the measurement errors have a significant effect on the best performing parameter vector. The erroneous data led to very different optimal parameter vectors. To overcome this problem and to find a set of robust parameter vectors, a geometrical approach based on Tukey's half space depth was used. The depth of the set of N randomly generated parameters was calculated with respect to the set with the best model performance (Nash-Sutclife efficiency was used for this study for each parameter vector. Based on the depth of parameter vectors, one can find a set of robust parameter vectors. The results show that the parameters chosen according to the above criteria have low sensitivity and perform well when transfered to a different time period. The method is demonstrated on the upper Neckar catchment in Germany. The conceptual HBV model was used for this study.

  10. Robust transient dynamics and brain functions.

    Science.gov (United States)

    Rabinovich, Mikhail I; Varona, Pablo

    2011-01-01

    In the last few decades several concepts of dynamical systems theory (DST) have guided psychologists, cognitive scientists, and neuroscientists to rethink about sensory motor behavior and embodied cognition. A critical step in the progress of DST application to the brain (supported by modern methods of brain imaging and multi-electrode recording techniques) has been the transfer of its initial success in motor behavior to mental function, i.e., perception, emotion, and cognition. Open questions from research in genetics, ecology, brain sciences, etc., have changed DST itself and lead to the discovery of a new dynamical phenomenon, i.e., reproducible and robust transients that are at the same time sensitive to informational signals. The goal of this review is to describe a new mathematical framework - heteroclinic sequential dynamics - to understand self-organized activity in the brain that can explain certain aspects of robust itinerant behavior. Specifically, we discuss a hierarchy of coarse-grain models of mental dynamics in the form of kinetic equations of modes. These modes compete for resources at three levels: (i) within the same modality, (ii) among different modalities from the same family (like perception), and (iii) among modalities from different families (like emotion and cognition). The analysis of the conditions for robustness, i.e., the structural stability of transient (sequential) dynamics, give us the possibility to explain phenomena like the finite capacity of our sequential working memory - a vital cognitive function -, and to find specific dynamical signatures - different kinds of instabilities - of several brain functions and mental diseases.

  11. Robust transient dynamics and brain functions

    Directory of Open Access Journals (Sweden)

    Mikhail I Rabinovich

    2011-06-01

    Full Text Available In the last few decades several concepts of Dynamical Systems Theory (DST have guided psychologists, cognitive scientists, and neuroscientists to rethink about sensory motor behavior and embodied cognition. A critical step in the progress of DST application to the brain (supported by modern methods of brain imaging and multi-electrode recording techniques has been the transfer of its initial success in motor behavior to mental function, i.e., perception, emotion, and cognition. Open questions from research in genetics, ecology, brain sciences, etc. have changed DST itself and lead to the discovery of a new dynamical phenomenon, i.e., reproducible and robust transients that are at the same time sensitive to informational signals. The goal of this review is to describe a new mathematical framework -heteroclinic sequential dynamics- to understand self-organized activity in the brain that can explain certain aspects of robust itinerant behavior. Specifically, we discuss a hierarchy of coarse-grain models of mental dynamics in the form of kinetic equations of modes. These modes compete for resources at three levels: (i within the same modality, (ii among different modalities from the same family (like perception, and (iii among modalities from different families (like emotion and cognition. The analysis of the conditions for robustness, i.e., the structural stability of transient (sequential dynamics, give us the possibility to explain phenomena like the finite capacity of our sequential working memory -a vital cognitive function-, and to find specific dynamical signatures -different kinds of instabilities- of several brain functions and mental diseases.

  12. Fast and robust shape diameter function.

    Science.gov (United States)

    Chen, Shuangmin; Liu, Taijun; Shu, Zhenyu; Xin, Shiqing; He, Ying; Tu, Changhe

    2018-01-01

    The shape diameter function (SDF) is a scalar function defined on a closed manifold surface, measuring the neighborhood diameter of the object at each point. Due to its pose oblivious property, SDF is widely used in shape analysis, segmentation and retrieval. However, computing SDF is computationally expensive since one has to place an inverted cone at each point and then average the penetration distances for a number of rays inside the cone. Furthermore, the shape diameters are highly sensitive to local geometric features as well as the normal vectors, hence diminishing their applications to real-world meshes which often contain rich geometric details and/or various types of defects, such as noise and gaps. In order to increase the robustness of SDF and promote it to a wide range of 3D models, we define SDF by offsetting the input object a little bit. This seemingly minor change brings three significant benefits: First, it allows us to compute SDF in a robust manner since the offset surface is able to give reliable normal vectors. Second, it runs many times faster since at each point we only need to compute the penetration distance along a single direction, rather than tens of directions. Third, our method does not require watertight surfaces as the input-it supports both point clouds and meshes with noise and gaps. Extensive experimental results show that the offset-surface based SDF is robust to noise and insensitive to geometric details, and it also runs about 10 times faster than the existing method. We also exhibit its usefulness using two typical applications including shape retrieval and shape segmentation, and observe a significant improvement over the existing SDF.

  13. Robust topology optimization accounting for geometric imperfections

    DEFF Research Database (Denmark)

    Schevenels, M.; Jansen, M.; Lombaert, Geert

    2013-01-01

    performance. As a consequence, the actual structure may be far from optimal. In this paper, a robust approach to topology optimization is presented, taking into account two types of geometric imperfections: variations of (1) the crosssections and (2) the locations of structural elements. The first type......Topology optimization is a powerful method to optimize the performance of macro, micro, or nano structures. However, the geometry of the actual structure may differ from the optimized design due to manufacturing errors. Such geometric imperfections can have a significant impact on the structural...

  14. Robustness Analysis of Gene Regulatory Networks

    Science.gov (United States)

    Kadelka, Claus T.

    Cells generally manage to maintain stable phenotypes in the face of widely varying environmental conditions. This fact is particularly surprising since the key step of gene expression is fundamentally a stochastic process. Many hypotheses have been suggested to explain this robustness. First, the special topology of gene regulatory networks (GRNs) seems to be an important factor as they possess feedforward loops and certain other topological features much more frequently than expected. Second, genes often regulate each other in a canalizing fashion: there exists a dominance order amidst the regulators of a gene, which in silico leads to very robust phenotypes. Lastly, an entirely novel gene regulatory mechanism, discovered and studied during the last two decades, which is believed to play an important role in cancer, is shedding some light on how canalization may in fact take place as part of a cell's gene regulatory program. Short segments of single-stranded RNA, so-called microRNAs, which are embedded in several different types of feedforward loops, help smooth out noise and generate canalizing effects in gene regulation by overriding the effect of certain genes on others. Boolean networks and their multi-state extensions have been successfully used to model GRNs for many years. In this dissertation, GRNs are represented in the time- and state-discrete framework of Stochastic Discrete Dynamical Systems (SDDS), which captures the cell-inherent stochasticity. Each gene has finitely many different concentration levels and its concentration at the next time step is determined by a gene-specific update rule that depends on the current concentration of the gene's regulators. The update rules in published gene regulatory networks are often nested canalizing functions. In Chapter 2, this class of functions is introduced, generalized and analyzed with respect to its potential to confer robustness. Chapter 3 describes a simulation study, which supports the hypothesis that

  15. Robust Pseudo-Hierarchical Support Vector Clustering

    DEFF Research Database (Denmark)

    Hansen, Michael Sass; Sjöstrand, Karl; Olafsdóttir, Hildur

    2007-01-01

    Support vector clustering (SVC) has proven an efficient algorithm for clustering of noisy and high-dimensional data sets, with applications within many fields of research. An inherent problem, however, has been setting the parameters of the SVC algorithm. Using the recent emergence of a method...... for calculating the entire regularization path of the support vector domain description, we propose a fast method for robust pseudo-hierarchical support vector clustering (HSVC). The method is demonstrated to work well on generated data, as well as for detecting ischemic segments from multidimensional myocardial...

  16. Robust control technique for nuclear power plants

    International Nuclear Information System (INIS)

    Murphy, G.V.; Bailey, J.M.

    1989-03-01

    This report summarizes the linear quadratic Guassian (LQG) design technique with loop transfer recovery (LQG/LTR) for design of control systems. The concepts of return ratio, return difference, inverse return difference, and singular values are summarized. The LQG/LTR design technique allows the synthesis of a robust control system. To illustrate the LQG/LTR technique, a linearized model of a simple process has been chosen. The process has three state variables, one input, and one output. Three control system design methods are compared: LQG, LQG/LTR, and a proportional plus integral controller (PI). 7 refs., 20 figs., 6 tabs

  17. ROBUST CONTROL OF OSCILLATIONS IN AGRICULTURAL TRACTORS

    DEFF Research Database (Denmark)

    Andersen, T. O.; Hansen, M. R.; Conrad, Finn

    2003-01-01

    for agricultural tractors equiped with hicth and implements. A control strategy is developed to make the implement counteract the movement of the tractor and thereby reducing the pitching oscillation. The control strategy is based on a linear plant model with constant or slowly varying parameters. Using...... element acting between the vehicle and the ground but the suspension and damping properties of the tires cannotmeet the demands for fast, safe and comfortable road transportation. In this paper, the mentioned phenomenon was undertaken for investigation with special focus on robust oscillations...

  18. Integrated robust controller for vehicle path following

    International Nuclear Information System (INIS)

    Mashadi, Behrooz; Ahmadizadeh, Pouyan; Majidi, Majid; Mahmoodi-Kaleybar, Mehdi

    2015-01-01

    The design of an integrated 4WS+DYC control system to guide a vehicle on a desired path is presented. The lateral dynamics of the path follower vehicle is formulated by considering important parameters. To reduce the effect of uncertainties in vehicle parameters, a robust controller is designed based on a μ-synthesis approach. Numerical simulations are performed using a nonlinear vehicle model in MATLAB environment in order to investigate the effectiveness of the designed controller. Results of simulations show that the controller has a profound ability to making the vehicle track the desired path in the presence of uncertainties

  19. Reconfigurable Robust Routing for Mobile Outreach Network

    Science.gov (United States)

    Lin, Ching-Fang

    2010-01-01

    The Reconfigurable Robust Routing for Mobile Outreach Network (R3MOO N) provides advanced communications networking technologies suitable for the lunar surface environment and applications. The R3MOON techn ology is based on a detailed concept of operations tailored for luna r surface networks, and includes intelligent routing algorithms and wireless mesh network implementation on AGNC's Coremicro Robots. The product's features include an integrated communication solution inco rporating energy efficiency and disruption-tolerance in a mobile ad h oc network, and a real-time control module to provide researchers an d engineers a convenient tool for reconfiguration, investigation, an d management.

  20. PID control with robust disturbance feedback control

    DEFF Research Database (Denmark)

    Kawai, Fukiko; Vinther, Kasper; Andersen, Palle

    2015-01-01

    Disturbance Feedback Control (DFC) is a technique, originally proposed by Fuji Electric, for augmenting existing control systems with an extra feedback for attenuation of disturbances and model errors. In this work, we analyze the robustness and performance of a PID-based control system with DFC...... and performance (if such gains exist). Finally, two different simulation case studies are evaluated and compared. Our numerical studies indicate that better performance can be achieved with the proposed method compared with a conservatively tuned PID controller and comparable performance can be achieved when...... compared with an H-infinity controller....

  1. Hybrid Dynamical Systems Modeling, Stability, and Robustness

    CERN Document Server

    Goebel, Rafal; Teel, Andrew R

    2012-01-01

    Hybrid dynamical systems exhibit continuous and instantaneous changes, having features of continuous-time and discrete-time dynamical systems. Filled with a wealth of examples to illustrate concepts, this book presents a complete theory of robust asymptotic stability for hybrid dynamical systems that is applicable to the design of hybrid control algorithms--algorithms that feature logic, timers, or combinations of digital and analog components. With the tools of modern mathematical analysis, Hybrid Dynamical Systems unifies and generalizes earlier developments in continuous-time and discret

  2. Robust surface roughness indices and morphological interpretation

    Science.gov (United States)

    Trevisani, Sebastiano; Rocca, Michele

    2016-04-01

    Geostatistical-based image/surface texture indices based on variogram (Atkison and Lewis, 2000; Herzfeld and Higginson, 1996; Trevisani et al., 2012) and on its robust variant MAD (median absolute differences, Trevisani and Rocca, 2015) offer powerful tools for the analysis and interpretation of surface morphology (potentially not limited to solid earth). In particular, the proposed robust index (Trevisani and Rocca, 2015) with its implementation based on local kernels permits the derivation of a wide set of robust and customizable geomorphometric indices capable to outline specific aspects of surface texture. The stability of MAD in presence of signal noise and abrupt changes in spatial variability is well suited for the analysis of high-resolution digital terrain models. Moreover, the implementation of MAD by means of a pixel-centered perspective based on local kernels, with some analogies to the local binary pattern approach (Lucieer and Stein, 2005; Ojala et al., 2002), permits to create custom roughness indices capable to outline different aspects of surface roughness (Grohmann et al., 2011; Smith, 2015). In the proposed poster, some potentialities of the new indices in the context of geomorphometry and landscape analysis will be presented. At same time, challenges and future developments related to the proposed indices will be outlined. Atkinson, P.M., Lewis, P., 2000. Geostatistical classification for remote sensing: an introduction. Computers & Geosciences 26, 361-371. Grohmann, C.H., Smith, M.J., Riccomini, C., 2011. Multiscale Analysis of Topographic Surface Roughness in the Midland Valley, Scotland. IEEE Transactions on Geoscience and Remote Sensing 49, 1220-1213. Herzfeld, U.C., Higginson, C.A., 1996. Automated geostatistical seafloor classification - Principles, parameters, feature vectors, and discrimination criteria. Computers and Geosciences, 22 (1), pp. 35-52. Lucieer, A., Stein, A., 2005. Texture-based landform segmentation of LiDAR imagery

  3. ANN-implemented robust vision model

    Science.gov (United States)

    Teng, Chungte; Ligomenides, Panos A.

    1991-02-01

    A robust vision model has been developed and implemented with a self-organizing/unsupervised artificial neural network (ANN) classifier-KART which is a novel hybrid model of a modified Kohonen''s feature map and the Carpenter/Grossberg''s ART architecture. The six moment invariants have been mapped onto a 7-dimensional unit hypersphere and have been applied to the KART classifier. In this paper the KART model will be presented. The non-adaptive neural implementations on the image processing and the moment invariant feature extraction will be discussed. In addition the simulation results that illustrate the capabilities of this model will also be provided. 1.

  4. Robustness of the Blandford-Znajek mechanism

    Energy Technology Data Exchange (ETDEWEB)

    Palenzuela, Carlos [Canadian Institute for Theoretical Astrophysics, Toronto, Ontario M5S 3H8 (Canada); Bona, Carles [Institute for Applied Computing with Community Code (IAC3), Universitat de les Illes Balears, Palma de Mallorca 07122 (Spain); Lehner, Luis; Reula, Oscar, E-mail: palen@cita.utoronto.ca [Department of Physics and Astronomy, Louisiana State University, Baton Rouge, LA 70802 (United States)

    2011-07-07

    The Blandford-Znajek (BZ) mechanism has long been regarded as a key ingredient in models attempting to explain powerful jets in AGNs, quasars, blazzars, etc. In such a mechanism, energy is extracted from a rotating black hole and dissipated at a load at far distances. In this work we examine the behavior of the BZ mechanism with respect to different boundary conditions, revealing the robustness of the mechanism upon variation of these conditions. Consequently, this work closes a gap in our understanding of this important scenario.

  5. Heuristics for the Robust Coloring Problem

    Directory of Open Access Journals (Sweden)

    Miguel Ángel Gutiérrez Andrade

    2011-03-01

    Full Text Available Let $G$ and $\\bar{G}$ be complementary graphs. Given a penalty function defined on the edges of $G$, we will say that the rigidity of a $k$-coloring of $G$ is the sum of the penalties of the edges of G joining vertices of the same color. Based on the previous definition, the Robust Coloring Problem (RCP is stated as the search of the minimum rigidity $k$-coloring. In this work a comparison of heuristics based on simulated annealing, GRASP and scatter search is presented. These are the best results for the RCP that have been obtained.

  6. Robust Design of Sounds in Mechanical Mechanisms

    DEFF Research Database (Denmark)

    Boegedal Jensen, Annemette; Munch, Natasja; Howard, Thomas J.

    2015-01-01

    Current practices for creating a desired sound by a mechanical mechanism are irrelative design-build-test processes. It seems that very little guidance is available relating design to the sound output. The focus of this study was to identify, which parameters that affect the sound output of a click...... mechanism consisting of a toothed rack and a click arm. First several geometries of the teeth and the click arm’s head were investigated to identify the most robust and repeatable design. It was found that a flat surface in the valleys between the teeth is very beneficial in relation to repeatability...... mechanisms....

  7. Robust laser frequency stabilization by serrodyne modulation.

    Science.gov (United States)

    Kohlhaas, Ralf; Vanderbruggen, Thomas; Bernon, Simon; Bertoldi, Andrea; Landragin, Arnaud; Bouyer, Philippe

    2012-03-15

    We report the relative frequency stabilization of a distributed feedback erbium-doped fiber laser on an optical cavity by serrodyne frequency shifting. A correction bandwidth of 2.3 MHz and a dynamic range of 220 MHz are achieved, which leads to a strong robustness against large disturbances up to high frequencies. We demonstrate that serrodyne frequency shifting reaches a higher correction bandwidth and lower relative frequency noise level compared to a standard acousto-optical modulator based scheme. Our results allow us to consider promising applications in the absolute frequency stabilization of lasers on optical cavities.

  8. Robustness of mission plans for unmanned aircraft

    Science.gov (United States)

    Niendorf, Moritz

    This thesis studies the robustness of optimal mission plans for unmanned aircraft. Mission planning typically involves tactical planning and path planning. Tactical planning refers to task scheduling and in multi aircraft scenarios also includes establishing a communication topology. Path planning refers to computing a feasible and collision-free trajectory. For a prototypical mission planning problem, the traveling salesman problem on a weighted graph, the robustness of an optimal tour is analyzed with respect to changes to the edge costs. Specifically, the stability region of an optimal tour is obtained, i.e., the set of all edge cost perturbations for which that tour is optimal. The exact stability region of solutions to variants of the traveling salesman problems is obtained from a linear programming relaxation of an auxiliary problem. Edge cost tolerances and edge criticalities are derived from the stability region. For Euclidean traveling salesman problems, robustness with respect to perturbations to vertex locations is considered and safe radii and vertex criticalities are introduced. For weighted-sum multi-objective problems, stability regions with respect to changes in the objectives, weights, and simultaneous changes are given. Most critical weight perturbations are derived. Computing exact stability regions is intractable for large instances. Therefore, tractable approximations are desirable. The stability region of solutions to relaxations of the traveling salesman problem give under approximations and sets of tours give over approximations. The application of these results to the two-neighborhood and the minimum 1-tree relaxation are discussed. Bounds on edge cost tolerances and approximate criticalities are obtainable likewise. A minimum spanning tree is an optimal communication topology for minimizing the cumulative transmission power in multi aircraft missions. The stability region of a minimum spanning tree is given and tolerances, stability balls

  9. Active vibration control by robust control techniques

    International Nuclear Information System (INIS)

    Lohar, F.A.

    2001-01-01

    This paper studies active vibration control of multi-degree-of-freedom system. The control techniques considered are LTR, H/sup 2/ and H/sup infinite/. The results show that LTR controls the vibration but its respective settling time is higher than that of the other techniques. The control performance of H/sup infinite/ control is similar to that of H/sup 2/ control in the case of it weighting functions. However, H/sup infinite/ control is superior to H/sup 2/ control with respect to robustness, steady state error and settling time. (author)

  10. Integrated robust controller for vehicle path following

    Energy Technology Data Exchange (ETDEWEB)

    Mashadi, Behrooz; Ahmadizadeh, Pouyan, E-mail: p-ahmadizadeh@iust.ac.ir; Majidi, Majid, E-mail: m-majidi@iust.ac.ir [Iran University of Science and Technology, School of Automotive Engineering (Iran, Islamic Republic of); Mahmoodi-Kaleybar, Mehdi, E-mail: m-mahmoodi-k@iust.ac.ir [Iran University of Science and Technology, School of Mechanical Engineering (Iran, Islamic Republic of)

    2015-02-15

    The design of an integrated 4WS+DYC control system to guide a vehicle on a desired path is presented. The lateral dynamics of the path follower vehicle is formulated by considering important parameters. To reduce the effect of uncertainties in vehicle parameters, a robust controller is designed based on a μ-synthesis approach. Numerical simulations are performed using a nonlinear vehicle model in MATLAB environment in order to investigate the effectiveness of the designed controller. Results of simulations show that the controller has a profound ability to making the vehicle track the desired path in the presence of uncertainties.

  11. Efficient and Robust Paramyxoviridae Reverse Genetics Systems

    Science.gov (United States)

    Beaty, Shannon M.; Won, Sohui T.; Hong, Patrick; Lyons, Michael; Vigant, Frederic; Freiberg, Alexander N.; tenOever, Benjamin R.; Duprex, W. Paul

    2017-01-01

    ABSTRACT The notoriously low efficiency of Paramyxoviridae reverse genetics systems has posed a limiting barrier to the study of viruses in this family. Previous approaches to reverse genetics have utilized a wide variety of techniques to overcome the technical hurdles. Although robustness (i.e., the number of attempts that result in successful rescue) has been improved in some systems with the use of stable cell lines, the efficiency of rescue (i.e., the proportion of transfected cells that yield at least one successful rescue event) has remained low. We have substantially increased rescue efficiency for representative viruses from all five major Paramyxoviridae genera (from ~1 in 106-107 to ~1 in 102-103 transfected cells) by the addition of a self-cleaving hammerhead ribozyme (Hh-Rbz) sequence immediately preceding the start of the recombinant viral antigenome and the use of a codon-optimized T7 polymerase (T7opt) gene to drive paramyxovirus rescue. Here, we report a strategy for robust, reliable, and high-efficiency rescue of paramyxovirus reverse genetics systems, featuring several major improvements: (i) a vaccinia virus-free method, (ii) freedom to use any transfectable cell type for viral rescue, (iii) a single-step transfection protocol, and (iv) use of the optimal T7 promoter sequence for high transcription levels from the antigenomic plasmid without incorporation of nontemplated G residues. The robustness of our T7opt-HhRbz system also allows for greater latitude in the ratios of transfected accessory plasmids used that result in successful rescue. Thus, our system may facilitate the rescue and interrogation of the increasing number of emerging paramyxoviruses. IMPORTANCE The ability to manipulate the genome of paramyxoviruses and evaluate the effects of these changes at the phenotypic level is a powerful tool for the investigation of specific aspects of the viral life cycle and viral pathogenesis. However, reverse genetics systems for paramyxoviruses

  12. Robust technique allowing manufacturing superoleophobic surfaces

    Science.gov (United States)

    Bormashenko, Edward; Grynyov, Roman; Chaniel, Gilad; Taitelbaum, Haim; Bormashenko, Yelena

    2013-04-01

    We report the robust technique allowing manufacturing of superhydrophobic and oleophobic (omniphobic) surfaces with industrial grade low density polyethylene. The reported process includes two stages: (1) hot embossing of polyethylene with micro-scaled steel gauzes; (2) treatment of embossed surfaces with cold radiofrequency plasma of tetrafluoromethane. The reported surfaces demonstrate not only pronounced superhydrophobicity but also superoleophobicity. Superoleophobicity results from the hierarchical nano-scaled topography of fluorinated polyethylene surface. The observed superoleophobicity is strengthened by the hydrophobic recovery. The stability of the Cassie wetting regime was studied.

  13. Robust Bioinformatics Recognition with VLSI Biochip Microsystem

    Science.gov (United States)

    Lue, Jaw-Chyng L.; Fang, Wai-Chi

    2006-01-01

    A microsystem architecture for real-time, on-site, robust bioinformatic patterns recognition and analysis has been proposed. This system is compatible with on-chip DNA analysis means such as polymerase chain reaction (PCR)amplification. A corresponding novel artificial neural network (ANN) learning algorithm using new sigmoid-logarithmic transfer function based on error backpropagation (EBP) algorithm is invented. Our results show the trained new ANN can recognize low fluorescence patterns better than the conventional sigmoidal ANN does. A differential logarithmic imaging chip is designed for calculating logarithm of relative intensities of fluorescence signals. The single-rail logarithmic circuit and a prototype ANN chip are designed, fabricated and characterized.

  14. Parametric robustness of the reactor control system

    International Nuclear Information System (INIS)

    Lee, Yoon Joon; Kim, Sin

    1998-01-01

    The parametric analysis method is applied to the reactor control system. The mathematical reactor model is discussed in terms of the parametric uncertainties. The Tsyplin-Polyak locus, based on the boundary crossing theorem, shows the reactor plant has an intrinsic stability. A simple controller is incorporated to the plant to configure the overall closed loop system. Then parametric stability margins are obtained for the controller constants. The results show that a new design constraint of the controller robustness with respect to overall system should be considered for the controller design of an uncertain system

  15. Predictors of Timely Prenatal Care Initiation and Adequate Utilization in a Sample of Late Adolescent Texas Latinas.

    Science.gov (United States)

    Torres, Rosamar; Kehoe, Priscilla; Heilemann, MarySue V

    2018-03-01

    Little is known of late adolescent Texas Latinas' prenatal care perceptions or how these perceptions predict timely prenatal care initiation or adequate utilization. Hence, the purpose of this study is to describe and compare these perceptions between participants with timely versus late prenatal care initiation and adequate, intermediate, and inadequate prenatal care utilization; and to determine predictors of timely prenatal care initiation and adequate utilization. Fifty-four postpartum Latinas were recruited through social media. Eligibility criteria were 18 to 21 years old, Texas-born, primiparous, uncomplicated pregnancy/delivery, and English literate. Prenatal care perceptions were measured with the Revised Better Babies Survey and Access Barriers to Care Index. Participants had favorable views of prenatal care benefits; however, not living with the baby's father predicted inadequate prenatal care, Wald χ 2 (1) = 4.93, p = .026. Perceived benefits of timely and adequate prenatal care predicted timely prenatal care initiation, χ 2 (1) = 7.47, p = .006. Self-reported depression during pregnancy predicted timely entry into prenatal care, χ 2 (1) = 4.73, p = .03. Participants' positive prenatal care perceptions did not predict adequate prenatal care utilization, indicating that barriers serve as powerful obstacles in late adolescent Texas Latinas.

  16. Frequency of Adequate Endometrial Biopsy in Evaluation of Postmenopausal Women With Benign Endometrial Cells on Pap Test.

    Science.gov (United States)

    Hastings, Jeffrey W; Alston, Meredith J; Mazzoni, Sara E; Stickrath, Elaine

    2017-10-01

    The aim of the study was to determine the frequency that endometrial biopsies (EMBs) performed on postmenopausal (PMP) women with benign endometrial cells (BECs) on Pap test are adequate for assessing malignancy or hyperplasia. This is a case series including all PMP women older than 55 years at a single academic institution between January 2008 and September 2015 with a Pap test result including BEC. Patients were identified via an internal cytology database. Patient data, the ability to obtain an EMB, and the result of the EMB were collected. An adequate EMB was defined as the presence of glands and stroma sufficient to assess for endometrial hyperplasia and/or malignancy. Descriptive statistics were performed, and then univariable and logistic regression analyses were used to evaluate associations of patient factors and adequacy of EMB. One hundred sixteen women met inclusion criteria. One hundred seven had an EMB scheduled (92%) and of those 91 EMBs were obtained (85%). Of the obtained biopsies, 63 were inadequate to rule out the diagnosis of hyperplasia and/or malignancy (69%). Of these, 19 patients underwent pelvic ultrasound (30%), 12 followed up with repeat Pap test (19%), and 4 underwent dilation and curettage (6%). Of the adequate biopsies, 5 had a diagnosis of hyperplasia (18%) and 5 with malignancy (18%). In PMP women with BEC on Pap test, adequate EMB was only obtained in 31% of patients. Most patients without an adequate biopsy had no further workup of their abnormal Pap test.

  17. Modelling energy demand of developing countries: Are the specific features adequately captured?

    International Nuclear Information System (INIS)

    Bhattacharyya, Subhes C.; Timilsina, Govinda R.

    2010-01-01

    This paper critically reviews existing energy demand forecasting methodologies highlighting the methodological diversities and developments over the past four decades in order to investigate whether the existing energy demand models are appropriate for capturing the specific features of developing countries. The study finds that two types of approaches, econometric and end-use accounting, are commonly used in the existing energy demand models. Although energy demand models have greatly evolved since the early seventies, key issues such as the poor-rich and urban-rural divides, traditional energy resources and differentiation between commercial and non-commercial energy commodities are often poorly reflected in these models. While the end-use energy accounting models with detailed sectoral representations produce more realistic projections as compared to the econometric models, they still suffer from huge data deficiencies especially in developing countries. Development and maintenance of more detailed energy databases, further development of models to better reflect developing country context and institutionalizing the modelling capacity in developing countries are the key requirements for energy demand modelling to deliver richer and more reliable input to policy formulation in developing countries.

  18. NASA Early Career Fellowship Program

    Science.gov (United States)

    Smith, H. D.

    2012-12-01

    The Early Career Fellowship program was established in 2005 to facilitate the integration of outstanding early career planetary science researchers into established research funding programs by providing tools and experience useful to maintain a successful research program. Executing a successful research program requires a few key elements such as: successful proposal writing; adequate (paid) research time; management of a laboratory; collaboration and networking; frequent and high-quality publications; and adequate start-up equipment funds. These elements may be particularly critical for early career researchers searching for a tenure- track or equivalent position. The Early Career Fellowship program recognizes the importance of these skills and provides extra funding and resources to begin a successful research program. For consideration into The Early Career Fellowship program, the candidate needs to be the P. I. or Science P.I. of a funded research proposal from one of the participating R&A program areas, be within 7 years of earning a PhD, hold a non-tenure track position, and indicate the early career candidacy when submitting the research proposal. If the research proposal is funded and the discipline scientist nominates the candidate as an early career fellow, the candidate is then considered a Fellow and eligible to propose for Step 2. Upon obtaining a tenure-track equivalent position the Fellow submits a Step 2 proposal for up to one hundred thousand dollars in start-up funds. Start-up funds may be used for salary; undergraduate and/or graduate research assistants; supplies and instrument upgrades; travel to conferences, meetings, and advisory groups; time and travel for learning new skills; publication page charges; books and journal subscriptions; computer time and/or specialized software; and other justified research-specific needs. The early career fellowship program provides resources that a more established scientist would have acquired allowing

  19. Robust Design Impact Metrics: Measuring the effect of implementing and using Robust Design

    DEFF Research Database (Denmark)

    Ebro, Martin; Olesen, Jesper; Howard, Thomas J.

    2014-01-01

    Measuring the performance of an organisation’s product development process can be challenging due to the limited use of metrics in R&D. An organisation considering whether to use Robust Design as an integrated part of their development process may find it difficult to define whether it is relevant......, and afterwards measure the effect of having implemented it. This publication identifies and evaluates Robust Design-related metrics and finds that 2 metrics are especially useful: 1) Relative amount of R&D Resources spent after Design Verification and 2) Number of ‘change notes’ after Design Verification....... The metrics have been applied in a case company to test the assumptions made during the evaluation. It is concluded that the metrics are useful and relevant, but further work is necessary to make a proper overview and categorisation of different types of robustness related metrics....

  20. Transportation Infrastructure Robustness : Joint Engineering and Economic Analysis

    Science.gov (United States)

    2017-11-01

    The objectives of this study are to develop a methodology for assessing the robustness of transportation infrastructure facilities and assess the effect of damage to such facilities on travel demand and the facilities users welfare. The robustness...

  1. Spatial reversal learning is robust to total sleep deprivation

    NARCIS (Netherlands)

    Leenaars, C.H.; Joosten, R.N.J.M.; Kramer, M.; Post, G.; Eggels, L.; Wuite, M.; Dematteis, M.; Feenstra, M.G.P.; van Someren, E.J.W.

    2012-01-01

    Sleep deprivation affects cognitive functions that depend on the prefrontal cortex (PFC) such as cognitive flexibility, and the consolidation of newly learned information. The identification of cognitive processes that are either robustly sensitive or robustly insensitive to the same experimental

  2. Multidisciplinary Design Optimization for High Reliability and Robustness

    National Research Council Canada - National Science Library

    Grandhi, Ramana

    2005-01-01

    .... Over the last 3 years Wright State University has been applying analysis tools to predict the behavior of critical disciplines to produce highly robust torpedo designs using robust multi-disciplinary...

  3. Modulation of Lactobacillus plantarum gastrointestinal robustness by fermentation conditions enables identification of bacterial robustness markers.

    Directory of Open Access Journals (Sweden)

    Hermien van Bokhorst-van de Veen

    Full Text Available BACKGROUND: Lactic acid bacteria (LAB are applied worldwide in the production of a variety of fermented food products. Additionally, specific Lactobacillus species are nowadays recognized for their health-promoting effects on the consumer. To optimally exert such beneficial effects, it is considered of great importance that these probiotic bacteria reach their target sites in the gut alive. METHODOLOGY/PRINCIPAL FINDINGS: In the accompanying manuscript by Bron et al. the probiotic model organism Lactobacillus plantarum WCFS1 was cultured under different fermentation conditions, which was complemented by the determination of the corresponding molecular responses by full-genome transcriptome analyses. Here, the gastrointestinal (GI survival of the cultures produced was assessed in an in vitro assay. Variations in fermentation conditions led to dramatic differences in GI-tract survival (up to 7-log and high robustness could be associated with low salt and low pH during the fermentations. Moreover, random forest correlation analyses allowed the identification of specific transcripts associated with robustness. Subsequently, the corresponding genes were targeted by genetic engineering, aiming to enhance robustness, which could be achieved for 3 of the genes that negatively correlated with robustness and where deletion derivatives displayed enhanced survival compared to the parental strain. Specifically, a role in GI-tract survival could be confirmed for the lp_1669-encoded AraC-family transcription regulator, involved in capsular polysaccharide remodeling, the penicillin-binding protein Pbp2A involved in peptidoglycan biosynthesis, and the Na(+/H(+ antiporter NapA3. Moreover, additional physiological analysis established a role for Pbp2A and NapA3 in bile salt and salt tolerance, respectively. CONCLUSION: Transcriptome trait matching enabled the identification of biomarkers for bacterial (gut-robustness, which is important for our molecular

  4. Change Point Detection with Robust Control Chart

    Directory of Open Access Journals (Sweden)

    Ng Kooi Huat

    2011-01-01

    Full Text Available Monitoring a process over time using a control chart allows quick detection of unusual states. In phase I, some historical process data, assumed to come from an in-control process, are used to construct the control limits. In Phase II, the process is monitored for an ongoing basis using control limits from Phase I. In Phase II, observations falling outside the control limits or unusual patterns of observations signal that the process has shifted from in-control process settings. Such signals trigger a search for assignable cause and, if the cause is found, corrective action will be implemented to prevent its recurrence. The purpose of this paper is to introduce a new methodology appropriate for constructing a robust control chart when a nonnormal or a contaminated data that may arise in phase I state. Through extensive Monte Carlo simulations, we examine the behaviors and performances of the proposed MM robust control chart when there is a process shift in mean.

  5. Robustizing Circuit Optimization using Huber Functions

    DEFF Research Database (Denmark)

    Bandler, John W.; Biernacki, Radek M.; Chen, Steve H.

    1993-01-01

    The authors introduce a novel approach to 'robustizing' microwave circuit optimization using Huber functions, both two-sided and one-sided. They compare Huber optimization with l/sub 1/, l/sub 2/, and minimax methods in the presence of faults, large and small measurement errors, bad starting poin......, a preliminary optimization by selecting a small number of dominant variables. It is demonstrated, through multiplexer optimization, that the one-sided Huber function can be more effective and efficient than minimax in overcoming a bad starting point.......The authors introduce a novel approach to 'robustizing' microwave circuit optimization using Huber functions, both two-sided and one-sided. They compare Huber optimization with l/sub 1/, l/sub 2/, and minimax methods in the presence of faults, large and small measurement errors, bad starting points......, and statistical uncertainties. They demonstrate FET statistical modeling, multiplexer optimization, analog fault location, and data fitting. They extend the Huber concept by introducing a 'one-sided' Huber function for large-scale optimization. For large-scale problems, the designer often attempts, by intuition...

  6. Biometric feature embedding using robust steganography technique

    Science.gov (United States)

    Rashid, Rasber D.; Sellahewa, Harin; Jassim, Sabah A.

    2013-05-01

    This paper is concerned with robust steganographic techniques to hide and communicate biometric data in mobile media objects like images, over open networks. More specifically, the aim is to embed binarised features extracted using discrete wavelet transforms and local binary patterns of face images as a secret message in an image. The need for such techniques can arise in law enforcement, forensics, counter terrorism, internet/mobile banking and border control. What differentiates this problem from normal information hiding techniques is the added requirement that there should be minimal effect on face recognition accuracy. We propose an LSB-Witness embedding technique in which the secret message is already present in the LSB plane but instead of changing the cover image LSB values, the second LSB plane will be changed to stand as a witness/informer to the receiver during message recovery. Although this approach may affect the stego quality, it is eliminating the weakness of traditional LSB schemes that is exploited by steganalysis techniques for LSB, such as PoV and RS steganalysis, to detect the existence of secrete message. Experimental results show that the proposed method is robust against PoV and RS attacks compared to other variants of LSB. We also discussed variants of this approach and determine capacity requirements for embedding face biometric feature vectors while maintain accuracy of face recognition.

  7. Making Activity Recognition Robust against Deceptive Behavior.

    Directory of Open Access Journals (Sweden)

    Sohrab Saeb

    Full Text Available Healthcare services increasingly use the activity recognition technology to track the daily activities of individuals. In some cases, this is used to provide incentives. For example, some health insurance companies offer discount to customers who are physically active, based on the data collected from their activity tracking devices. Therefore, there is an increasing motivation for individuals to cheat, by making activity trackers detect activities that increase their benefits rather than the ones they actually do. In this study, we used a novel method to make activity recognition robust against deceptive behavior. We asked 14 subjects to attempt to trick our smartphone-based activity classifier by making it detect an activity other than the one they actually performed, for example by shaking the phone while seated to make the classifier detect walking. If they succeeded, we used their motion data to retrain the classifier, and asked them to try to trick it again. The experiment ended when subjects could no longer cheat. We found that some subjects were not able to trick the classifier at all, while others required five rounds of retraining. While classifiers trained on normal activity data predicted true activity with ~38% accuracy, training on the data gathered during the deceptive behavior increased their accuracy to ~84%. We conclude that learning the deceptive behavior of one individual helps to detect the deceptive behavior of others. Thus, we can make current activity recognition robust to deception by including deceptive activity data from a few individuals.

  8. Robustness Assessment of Building Structures under Explosion

    Directory of Open Access Journals (Sweden)

    Mark Waggoner

    2012-12-01

    Full Text Available Over the past decade, much research has focused on the behaviour of structures following the failure of a key structural component. Particular attention has been given to sudden column loss, though questions remain as to whether this event-independent scenario is relevant to actual extreme events such as explosion. Few studies have been conducted to assess the performance of floor slabs above a failed column, and the computational tools used have not been validated against experimental results. The research program presented in this paper investigates the adequacy of sudden column loss as an idealisation of local damage caused by realistic explosion events, and extends prior work by combining the development of accurate computational models with large-scale testing of a typical floor system in a prototypical steel-framed structure. The floor system consists of corrugated decking topped by a lightly reinforced concrete slab that is connected to the floor beams through shear studs. The design is consistent with typical building practices in the US. The first test has been completed, and subsequent tests are currently being planned. This paper addresses the importance of robustness design for localized damage and includes a detailed description regarding how the research program advances the current state of knowledge for assessing robustness of compositely constructed steel-framed buildings.

  9. Robust Spacecraft Component Detection in Point Clouds.

    Science.gov (United States)

    Wei, Quanmao; Jiang, Zhiguo; Zhang, Haopeng

    2018-03-21

    Automatic component detection of spacecraft can assist in on-orbit operation and space situational awareness. Spacecraft are generally composed of solar panels and cuboidal or cylindrical modules. These components can be simply represented by geometric primitives like plane, cuboid and cylinder. Based on this prior, we propose a robust automatic detection scheme to automatically detect such basic components of spacecraft in three-dimensional (3D) point clouds. In the proposed scheme, cylinders are first detected in the iteration of the energy-based geometric model fitting and cylinder parameter estimation. Then, planes are detected by Hough transform and further described as bounded patches with their minimum bounding rectangles. Finally, the cuboids are detected with pair-wise geometry relations from the detected patches. After successive detection of cylinders, planar patches and cuboids, a mid-level geometry representation of the spacecraft can be delivered. We tested the proposed component detection scheme on spacecraft 3D point clouds synthesized by computer-aided design (CAD) models and those recovered by image-based reconstruction, respectively. Experimental results illustrate that the proposed scheme can detect the basic geometric components effectively and has fine robustness against noise and point distribution density.

  10. Robust Fringe Projection Profilometry via Sparse Representation.

    Science.gov (United States)

    Budianto; Lun, Daniel P K

    2016-04-01

    In this paper, a robust fringe projection profilometry (FPP) algorithm using the sparse dictionary learning and sparse coding techniques is proposed. When reconstructing the 3D model of objects, traditional FPP systems often fail to perform if the captured fringe images have a complex scene, such as having multiple and occluded objects. It introduces great difficulty to the phase unwrapping process of an FPP system that can result in serious distortion in the final reconstructed 3D model. For the proposed algorithm, it encodes the period order information, which is essential to phase unwrapping, into some texture patterns and embeds them to the projected fringe patterns. When the encoded fringe image is captured, a modified morphological component analysis and a sparse classification procedure are performed to decode and identify the embedded period order information. It is then used to assist the phase unwrapping process to deal with the different artifacts in the fringe images. Experimental results show that the proposed algorithm can significantly improve the robustness of an FPP system. It performs equally well no matter the fringe images have a simple or complex scene, or are affected due to the ambient lighting of the working environment.

  11. Robust Transfer Metric Learning for Image Classification.

    Science.gov (United States)

    Ding, Zhengming; Fu, Yun

    2017-02-01

    Metric learning has attracted increasing attention due to its critical role in image analysis and classification. Conventional metric learning always assumes that the training and test data are sampled from the same or similar distribution. However, to build an effective distance metric, we need abundant supervised knowledge (i.e., side/label information), which is generally inaccessible in practice, because of the expensive labeling cost. In this paper, we develop a robust transfer metric learning (RTML) framework to effectively assist the unlabeled target learning by transferring the knowledge from the well-labeled source domain. Specifically, RTML exploits knowledge transfer to mitigate the domain shift in two directions, i.e., sample space and feature space. In the sample space, domain-wise and class-wise adaption schemes are adopted to bridge the gap of marginal and conditional distribution disparities across two domains. In the feature space, our metric is built in a marginalized denoising fashion and low-rank constraint, which make it more robust to tackle noisy data in reality. Furthermore, we design an explicit rank constraint regularizer to replace the rank minimization NP-hard problem to guide the low-rank metric learning. Experimental results on several standard benchmarks demonstrate the effectiveness of our proposed RTML by comparing it with the state-of-the-art transfer learning and metric learning algorithms.

  12. Robust hashing for 3D models

    Science.gov (United States)

    Berchtold, Waldemar; Schäfer, Marcel; Rettig, Michael; Steinebach, Martin

    2014-02-01

    3D models and applications are of utmost interest in both science and industry. With the increment of their usage, their number and thereby the challenge to correctly identify them increases. Content identification is commonly done by cryptographic hashes. However, they fail as a solution in application scenarios such as computer aided design (CAD), scientific visualization or video games, because even the smallest alteration of the 3D model, e.g. conversion or compression operations, massively changes the cryptographic hash as well. Therefore, this work presents a robust hashing algorithm for 3D mesh data. The algorithm applies several different bit extraction methods. They are built to resist desired alterations of the model as well as malicious attacks intending to prevent correct allocation. The different bit extraction methods are tested against each other and, as far as possible, the hashing algorithm is compared to the state of the art. The parameters tested are robustness, security and runtime performance as well as False Acceptance Rate (FAR) and False Rejection Rate (FRR), also the probability calculation of hash collision is included. The introduced hashing algorithm is kept adaptive e.g. in hash length, to serve as a proper tool for all applications in practice.

  13. Maximum Correntropy Criterion for Robust Face Recognition.

    Science.gov (United States)

    He, Ran; Zheng, Wei-Shi; Hu, Bao-Gang

    2011-08-01

    In this paper, we present a sparse correntropy framework for computing robust sparse representations of face images for recognition. Compared with the state-of-the-art l(1)norm-based sparse representation classifier (SRC), which assumes that noise also has a sparse representation, our sparse algorithm is developed based on the maximum correntropy criterion, which is much more insensitive to outliers. In order to develop a more tractable and practical approach, we in particular impose nonnegativity constraint on the variables in the maximum correntropy criterion and develop a half-quadratic optimization technique to approximately maximize the objective function in an alternating way so that the complex optimization problem is reduced to learning a sparse representation through a weighted linear least squares problem with nonnegativity constraint at each iteration. Our extensive experiments demonstrate that the proposed method is more robust and efficient in dealing with the occlusion and corruption problems in face recognition as compared to the related state-of-the-art methods. In particular, it shows that the proposed method can improve both recognition accuracy and receiver operator characteristic (ROC) curves, while the computational cost is much lower than the SRC algorithms.

  14. Maintenance of exercise training benefits is associated with adequate milk and dairy products intake in elderly hypertensive subjects following detraining.

    Science.gov (United States)

    Moraes, Wilson Max Almeida Monteiro de; Santos, Neucilane Silveira Dos; Aguiar, Larissa Pereira; Sousa, Luís Gustavo Oliveira de

    2017-01-01

    To investigate whether maintenance of exercise training benefits is associated with adequate milk and dairy products intake in hypertensive elderly subjects after detraining. Twenty-eight elderly hypertensive patients with optimal clinical treatment underwent 16 weeks of multicomponent exercise training program followed by 6 weeks of detraining, and were classified according to milk and dairy products intake as low milk (exercise training, there was a significant reduction (pexercise training benefits related to pressure levels, lower extremity strength and aerobic capacity, is associated with adequate milk and dairy products intake in hypertensive elderly subjects following 6 weeks of detraining.

  15. A robust approach to the missile defence location problem

    NARCIS (Netherlands)

    Bloemen, A.A.F.; Evers, L.; Barros, A.I.; Monsuur, H.; Wagelmans, A.P.M.

    2011-01-01

    This paper proposes a model for determining a robust defence strategy against ballistic missile threat. Our approach takes into account a variety of possible future scenarios and different forms of robustness criteria, including the well-known absolute robustness criterion. We consider two problem

  16. Robust control of UAVs using the parameter space approach

    NARCIS (Netherlands)

    Abdelmoeti, Samer; Carloni, Raffaella

    2016-01-01

    In this paper a robust PID controller for quadrotor unmanned aerial vehicles is proposed that uses the pa- rameter space approach. Stability and robustness analyses are carried out in the controller parameter space to determine a set of stable controller gains that guarantee also robustness against

  17. A branch-and-bound approach for robust railway timetabling

    NARCIS (Netherlands)

    Maróti, Gábor

    2017-01-01

    This paper studies the robust cyclic timetabling problem. The goal is to modify a given reference timetable to enhance its robustness against small stochastic disturbances. The robustness is measured by the expected total delay of the realised timetable. Kroon et al. (Transp Res Part B

  18. Global robust stability for shunting inhibitory CNNs with delays.

    Science.gov (United States)

    Wang, Lingna; Lin, Yiping

    2004-08-01

    In this paper, the problem of global robust stability for shunting inhibitory cellular neural networks (SICNNs) is studied. A sufficient condition guaranteeing the network's global robust stability is established. The result can easily be used to verify globally robust stable networks. An example is given to illustrate that the conditions of our results are feasible.

  19. Automated robust registration of grossly misregistered whole-slide images with varying stains

    Science.gov (United States)

    Litjens, G.; Safferling, K.; Grabe, N.

    2016-03-01

    Cancer diagnosis and pharmaceutical research increasingly depend on the accurate quantification of cancer biomarkers. Identification of biomarkers is usually performed through immunohistochemical staining of cancer sections on glass slides. However, combination of multiple biomarkers from a wide variety of immunohistochemically stained slides is a tedious process in traditional histopathology due to the switching of glass slides and re-identification of regions of interest by pathologists. Digital pathology now allows us to apply image registration algorithms to digitized whole-slides to align the differing immunohistochemical stains automatically. However, registration algorithms need to be robust to changes in color due to differing stains and severe changes in tissue content between slides. In this work we developed a robust registration methodology to allow for fast coarse alignment of multiple immunohistochemical stains to the base hematyoxylin and eosin stained image. We applied HSD color model conversion to obtain a less stain color dependent representation of the whole-slide images. Subsequently, optical density thresholding and connected component analysis were used to identify the relevant regions for registration. Template matching using normalized mutual information was applied to provide initial translation and rotation parameters, after which a cost function-driven affine registration was performed. The algorithm was validated using 40 slides from 10 prostate cancer patients, with landmark registration error as a metric. Median landmark registration error was around 180 microns, which indicates performance is adequate for practical application. None of the registrations failed, indicating the robustness of the algorithm.

  20. Rectal cancer delivery of radiotherapy in adequate time and with adequate dose is influenced by treatment center, treatment schedule, and gender and is prognostic parameter for local control: Results of study CAO/ARO/AIO-94

    International Nuclear Information System (INIS)

    Fietkau, Rainer; Roedel, Claus; Hohenberger, Werner; Raab, Rudolf; Hess, Clemens; Liersch, Torsten; Becker, Heinz; Wittekind, Christian; Hutter, Matthias; Hager, Eva; Karstens, Johann; Ewald, Hermann; Christen, Norbert; Jagoditsch, Michael; Martus, Peter; Sauer, Rolf

    2007-01-01

    Purpose: The impact of the delivery of radiotherapy (RT) on treatment results in rectal cancer patients is unknown. Methods and Materials: The data from 788 patients with rectal cancer treated within the German CAO/AIO/ARO-94 phase III trial were analyzed concerning the impact of the delivery of RT (adequate RT: minimal radiation RT dose delivered, 4300 cGy for neoadjuvant RT or 4700 cGy for adjuvant RT; completion of RT in <44 days for neoadjuvant RT or <49 days for adjuvant RT) in different centers on the locoregional recurrence rate (LRR) and disease-free survival (DFS) at 5 years. The LRR, DFS, and delivery of RT were analyzed as endpoints in multivariate analysis. Results: A significant difference was found between the centers and the delivery of RT. The overall delivery of RT was a prognostic factor for the LRR (no RT, 29.6% ± 7.8%; inadequate RT, 21.2% ± 5.6%; adequate RT, 6.8% ± 1.4%; p = 0.0001) and DFS (no RT, 55.1% ± 9.1%; inadequate RT, 57.4% ± 6.3%; adequate RT, 69.1% ± 2.3%; p = 0.02). Postoperatively, delivery of RT was a prognostic factor for LRR on multivariate analysis (together with pathologic stage) but not for DFS (independent parameters, pathologic stage and age). Preoperatively, on multivariate analysis, pathologic stage, but not delivery of RT, was an independent prognostic parameter for LRR and DFS (together with adequate chemotherapy). On multivariate analysis, the treatment center, treatment schedule (neoadjuvant vs. adjuvant RT), and gender were prognostic parameters for adequate RT. Conclusion: Delivery of RT should be regarded as a prognostic factor for LRR in rectal cancer and is influenced by the treatment center, treatment schedule, and patient gender

  1. Expecting the Unexpected: Towards Robust Credential Infrastructure

    Science.gov (United States)

    Xu, Shouhuai; Yung, Moti

    Cryptographic credential infrastructures, such as Public key infrastructure (PKI), allow the building of trust relationships in electronic society and electronic commerce. At the center of credential infrastructures is the methodology of digital signatures. However, methods that assure that credentials and signed messages possess trustworthiness and longevity are not well understood, nor are they adequately addressed in both literature and practice. We believe that, as a basic engineering principle, these properties have to be built into the credential infrastructure rather than be treated as an after-thought since they are crucial to the long term success of this notion. In this paper we present a step in the direction of dealing with these issues. Specifically, we present the basic engineering reasoning as well as a model that helps understand (somewhat formally) the trustworthiness and longevity of digital signatures, and then we give basic mechanisms that help improve these notions.

  2. Mechanisms and coherences of robust design methodology: a robust design process proposal

    DEFF Research Database (Denmark)

    Göhler, Simon Moritz; Christensen, Martin Ebro; Howard, Thomas J.

    2016-01-01

    Although robust design (RD) methods are recognised as a way of developing mechanical products with consistent and predictable performance and quality, they do not experience widespread success in industry. One reason being the lack of a coherent RD process (RDP). In this contribution we analyse...

  3. Robust image segmentation using local robust statistics and correntropy-based K-means clustering

    Science.gov (United States)

    Huang, Chencheng; Zeng, Li

    2015-03-01

    It is an important work to segment the real world images with intensity inhomogeneity such as magnetic resonance (MR) and computer tomography (CT) images. In practice, such images are often polluted by noise which make them difficult to be segmented by traditional level set based segmentation models. In this paper, we propose a robust level set image segmentation model combining local with global fitting energies to segment noised images. In the proposed model, the local fitting energy is based on the local robust statistics (LRS) information of an input image, which can efficiently reduce the effects of the noise, and the global fitting energy utilizes the correntropy-based K-means (CK) method, which can adaptively emphasize the samples that are close to their corresponding cluster centers. By integrating the advantages of global information and local robust statistics characteristics, the proposed model can efficiently segment images with intensity inhomogeneity and noise. Then, a level set regularization term is used to avoid re-initialization procedures in the process of curve evolution. In addition, the Gaussian filter is utilized to keep the level set smoothing in the curve evolution process. The proposed model first appeared as a two-phase model and then extended to a multi-phase one. Experimental results show the advantages of our model in terms of accuracy and robustness to the noise. In particular, our method has been applied on some synthetic and real images with desirable results.

  4. Robust Optimisation Approach for Vehicle Routing Problems with Uncertainty

    Directory of Open Access Journals (Sweden)

    Liang Sun

    2015-01-01

    Full Text Available We formulated a solution procedure for vehicle routing problems with uncertainty (VRPU for short with regard to future demand and transportation cost. Unlike E-SDROA (expectation semideviation robust optimisation approach for solving the proposed problem, the formulation focuses on robust optimisation considering situations possibly related to bidding and capital budgets. Besides, numerical experiments showed significant increments in the robustness of the solutions without much loss in solution quality. The differences and similarities of the robust optimisation model and existing robust optimisation approaches were also compared.

  5. The Variation Management Framework (VMF) for Robust Design

    DEFF Research Database (Denmark)

    Howard, Thomas J.; Ebro, Martin; Eifler, Tobias

    2014-01-01

    Robust Design is an approach to reduce the effects of variation. There are numerous tools,methods and models associated with robust design, however, there is both a lack of a processmodel formalising the step of a robust design process and a framework tying the models together.In this paper we pr...... in the market place and identifies areaswhere action can be taken against variation. An additional benefit of the framework is that itmakes the link between visual/sensory/perceptual robustness, product robustness, and productionvariation (Six Sigma)....

  6. Robust Sliding Mode Control for Tokamaks

    Directory of Open Access Journals (Sweden)

    I. Garrido

    2012-01-01

    Full Text Available Nuclear fusion has arisen as an alternative energy to avoid carbon dioxide emissions, being the tokamak a promising nuclear fusion reactor that uses a magnetic field to confine plasma in the shape of a torus. However, different kinds of magnetohydrodynamic instabilities may affect tokamak plasma equilibrium, causing severe reduction of particle confinement and leading to plasma disruptions. In this sense, numerous efforts and resources have been devoted to seeking solutions for the different plasma control problems so as to avoid energy confinement time decrements in these devices. In particular, since the growth rate of the vertical instability increases with the internal inductance, lowering the internal inductance is a fundamental issue to address for the elongated plasmas employed within the advanced tokamaks currently under development. In this sense, this paper introduces a lumped parameter numerical model of the tokamak in order to design a novel robust sliding mode controller for the internal inductance using the transformer primary coil as actuator.

  7. Robust processing of optical flow of fluids.

    Science.gov (United States)

    Doshi, Ashish; Bors, Adrian G

    2010-09-01

    This paper proposes a new approach, coupling physical models and image estimation techniques, for modelling the movement of fluids. The fluid flow is characterized by turbulent movement and dynamically changing patterns which poses challenges to existing optical flow estimation methods. The proposed methodology, which relies on Navier-Stokes equations, is used for processing fluid optical flow by using a succession of stages such as advection, diffusion and mass conservation. A robust diffusion step jointly considering the local data geometry and its statistics is embedded in the proposed framework. The diffusion kernel is Gaussian with the covariance matrix defined by the local second derivatives. Such an anisotropic kernel is able to implicitly detect changes in the vector field orientation and to diffuse accordingly. A new approach is developed for detecting fluid flow structures such as vortices. The proposed methodology is applied on artificially generated vector fields as well as on various image sequences.

  8. Production monitoring system for understanding product robustness

    DEFF Research Database (Denmark)

    Boorla, Srinivasa Murthy; Howard, Thomas J.

    2016-01-01

    study is used to demonstrate how the monitoring system can be used to efficiently guide corrective action to improve product performance. It is claimed that the monitoring system can be used to dramatically cut the time taken to identify, planand execute corrective action related to typical quality...... to be seven days. Using the monitoring system for the PRECI‐IN case, similar corrective action would have been achieved almost immediately.......In the current quality paradigm, the performance of a product is kept within specification by ensuring that its parts are within specification. Product performance is then validated after final assembly. However, this does not control how robust the product performance is, i.e. how much...

  9. Robust feedback linearization for nonlinear processes control.

    Science.gov (United States)

    Rubio, José de Jesús

    2018-03-01

    In this research, a robust feedback linearization technique is studied for nonlinear processes control. The main contributions are described as follows: 1) Theory says that if a linearized controlled process is stable, then nonlinear process states are asymptotically stable, it is not satisfied in applications because some states converge to small values; therefore, a theorem based on Lyapunov theory is proposed to prove that if a linearized controlled process is stable, then nonlinear process states are uniformly stable. 2) Theory says that all the main and crossed states feedbacks should be considered for the nonlinear processes regulation, it makes more difficult to find the controller gains; consequently, only the main states feedbacks are utilized to obtain a satisfactory result in applications. This introduced strategy is applied in a fuel cell and a manipulator. Copyright © 2018 ISA. Published by Elsevier Ltd. All rights reserved.

  10. Robust digital processing of speech signals

    CERN Document Server

    Kovacevic, Branko; Veinović, Mladen; Marković, Milan

    2017-01-01

    This book focuses on speech signal phenomena, presenting a robustification of the usual speech generation models with regard to the presumed types of excitation signals, which is equivalent to the introduction of a class of nonlinear models and the corresponding criterion functions for parameter estimation. Compared to the general class of nonlinear models, such as various neural networks, these models possess good properties of controlled complexity, the option of working in “online” mode, as well as a low information volume for efficient speech encoding and transmission. Providing comprehensive insights, the book is based on the authors’ research, which has already been published, supplemented by additional texts discussing general considerations of speech modeling, linear predictive analysis and robust parameter estimation.

  11. Shock ignition: modelling and target design robustness

    Energy Technology Data Exchange (ETDEWEB)

    Ribeyre, X; Lafon, M; Schurtz, G; Olazabal-Loume, M; Breil, J; Galera, S; Weber, S, E-mail: ribeyre@celia.u-bordeaux1.f [Centre Lasers Intenses et Applications, Universite Bordeaux 1, CNRS, CEA, Universite Bordeaux 1, 351, cours de la Liberation, 33405 Talence (France)

    2009-12-15

    Shock ignition of a pre-compressed deuterium tritium fuel is considered here. When properly timed, a converging shock launched in the target prior to stagnation time strongly enhances the hot spot pressure. This allows ignition to be reached in a nonisobaric configuration. We show in this work that the igniting mechanism is pressure amplification by shock convergence and shock collision. The shock ignition applied to the HiPER target allows one to study the robustness of this method. It is shown that the spike energy is not a critical parameter and that the spike power delivered on the target depends mainly on the shell implosion velocity. Finally, a family of homothetic targets ignited with a shock wave is studied.

  12. Salmon: Robust Proxy Distribution for Censorship Circumvention

    Directory of Open Access Journals (Sweden)

    Douglas Frederick

    2016-10-01

    Full Text Available Many governments block their citizens’ access to much of the Internet. Simple workarounds are unreliable; censors quickly discover and patch them. Previously proposed robust approaches either have non-trivial obstacles to deployment, or rely on low-performance covert channels that cannot support typical Internet usage such as streaming video. We present Salmon, an incrementally deployable system designed to resist a censor with the resources of the “Great Firewall” of China. Salmon relies on a network of volunteers in uncensored countries to run proxy servers. Although any member of the public can become a user, Salmon protects the bulk of its servers from being discovered and blocked by the censor via an algorithm for quickly identifying malicious users. The algorithm entails identifying some users as especially trustworthy or suspicious, based on their actions. We impede Sybil attacks by requiring either an unobtrusive check of a social network account, or a referral from a trustworthy user.

  13. Robust processing of mining subsidence monitoring data

    Energy Technology Data Exchange (ETDEWEB)

    Wang Mingzhong; Huang Guogang [Pingdingshan Mining Bureau (China); Wang Yunjia; Guogangli [China Univ. of Mining and Technology, Xuzhou (China)

    1996-12-31

    Since China began to do research on mining subsidence in 1950s, more than one thousand lines have been observed. Yet, monitoring data sometimes contain quite a lot of outliers because of the limit of observation and geological mining conditions. In China, nowdays, the method of processing mining subsidence monitoring data is based on the principle of the least square method. It is possible to produce lower accuracy, less reliability, or even errors. For reason given above, the authors, according to Chinese actual situation, have done some research work on the robust processing of mining subsidence monitoring data in respect of how to get prediction parameters. The authors have derived related formulas, designed some computational programmes, done a great quantity of actual calculation and simulation, and achieved good results. (orig.)

  14. Robust high temperature oxygen sensor electrodes

    DEFF Research Database (Denmark)

    Lund, Anders

    Platinum is the most widely used material in high temperature oxygen sensor electrodes. However, platinum is expensive and the platinum electrode may, under certain conditions, suffer from poisoning, which is detrimental for an oxygen sensor. The objective of this thesis is to evaluate electrode...... materials as candidates for robust oxygen sensor electrodes. The present work focuses on characterising the electrochemical properties of a few electrode materials to understand which oxygen electrode processes are limiting for the response time of the sensor electrode. Three types of porous platinum......-Dansensor. The electrochemical properties of the electrodes were characterised by electrochemical impedance spectroscopy (EIS), and the structures were characterised by x-ray diffraction and electron microscopy. At an oxygen partial pressures of 0.2 bar, the response time of the sensor electrode was determined by oxygen...

  15. Robust PV Degradation Methodology and Application

    Energy Technology Data Exchange (ETDEWEB)

    Jordan, Dirk [National Renewable Energy Laboratory (NREL), Golden, CO (United States); Deline, Christopher A [National Renewable Energy Laboratory (NREL), Golden, CO (United States); Kurtz, Sarah [National Renewable Energy Laboratory (NREL), Golden, CO (United States); Kimball, Greg [SunPower; Anderson, Mike [SunPower

    2017-11-15

    The degradation rate plays an important role in predicting and assessing the long-term energy generation of PV systems. Many methods have been proposed for extracting the degradation rate from operational data of PV systems, but most of the published approaches are susceptible to bias due to inverter clipping, module soiling, temporary outages, seasonality, and sensor degradation. In this manuscript, we propose a methodology for determining PV degradation leveraging available modeled clear-sky irradiance data rather than site sensor data, and a robust year-over-year (YOY) rate calculation. We show the method to provide reliable degradation rate estimates even in the case of sensor drift, data shifts, and soiling. Compared with alternate methods, we demonstrate that the proposed method delivers the lowest uncertainty in degradation rate estimates for a fleet of 486 PV systems.

  16. On the Robustness of Poverty Predictors

    DEFF Research Database (Denmark)

    Arndt, Channing; Nhate, Virgulino; Silva, Patricia Castro Da

    Monitoring of poverty requires timely household budget data. However, such data are not available as frequently as needed for policy purposes. Recently, statistical methods have emerged to predict poverty overtime by combining detailed household consumption and expenditure data with more frequent...... data collected from other surveys. In this paper we compare poverty predictions for Mozambique using different source data to test the robustness of the predicted poverty statistics. A critical element in this exercise of predicting poverty overtime is the stability of the parameters that determine...... household consumption. We find that the assumption of stable consumption determinants does not hold for Mozambique during the time period examined. We also examine what drives the resulting predicted poverty statistics. The paper then considers the policy implications of these findings for Mozambique...

  17. Robust Circle Detection Using Harmony Search

    Directory of Open Access Journals (Sweden)

    Jaco Fourie

    2017-01-01

    Full Text Available Automatic circle detection is an important element of many image processing algorithms. Traditionally the Hough transform has been used to find circular objects in images but more modern approaches that make use of heuristic optimisation techniques have been developed. These are often used in large complex images where the presence of noise or limited computational resources make the Hough transform impractical. Previous research on the use of the Harmony Search (HS in circle detection showed that HS is an attractive alternative to many of the modern circle detectors based on heuristic optimisers like genetic algorithms and simulated annealing. We propose improvements to this work that enables our algorithm to robustly find multiple circles in larger data sets and still work on realistic images that are heavily corrupted by noisy edges.

  18. Robust retrieval of fine art paintings

    Science.gov (United States)

    Smolka, Bogdan; Lukac, Rastislav; Plataniotis, Konstantinos N.; Venetsanopoulos, Anastasios N.

    2003-10-01

    The rapid growth of image archives increases the need for efficient and fast tools that can retrieve and search through large amount of visual data. In this paper we propose an efficient method of extracting the image color content, which serves as an image digital signature, allowing to efficiently index and retrieve the content of large, heterogeneous multimedia databases. We apply the proposed method for the retrieval of images from the WEBMUSEUM Internet database, containing the collection of fine art images and show that the new method of image color representation is robust to image distorsions caused by resizing and compression and can be incorporated into existing retrieval systems which exploit the information on color content in digital images.

  19. Robust PV Degradation Methodology and Application

    Energy Technology Data Exchange (ETDEWEB)

    Jordan, Dirk [National Renewable Energy Laboratory (NREL), Golden, CO (United States); Deline, Christopher A [National Renewable Energy Laboratory (NREL), Golden, CO (United States); Kurtz, Sarah [National Renewable Energy Laboratory (NREL), Golden, CO (United States); Kimball, Gregory M. [SunPower Corporation; Anderson, Mike [SunPower Corporation

    2017-12-21

    The degradation rate plays an important role in predicting and assessing the long-term energy generation of photovoltaics (PV) systems. Many methods have been proposed for extracting the degradation rate from operational data of PV systems, but most of the published approaches are susceptible to bias due to inverter clipping, module soiling, temporary outages, seasonality, and sensor degradation. In this paper, we propose a methodology for determining PV degradation leveraging available modeled clear-sky irradiance data rather than site sensor data, and a robust year-over-year rate calculation. We show the method to provide reliable degradation rate estimates even in the case of sensor drift, data shifts, and soiling. Compared with alternate methods, we demonstrate that the proposed method delivers the lowest uncertainty in degradation rate estimates for a fleet of 486 PV systems.

  20. Robust High Performance Aquaporin based Biomimetic Membranes

    DEFF Research Database (Denmark)

    Helix Nielsen, Claus; Zhao, Yichun; Qiu, C.

    2013-01-01

    Aquaporins are water channel proteins with high water permeability and solute rejection, which makes them promising for preparing high-performance biomimetic membranes. Despite the growing interest in aquaporin-based biomimetic membranes (ABMs), it is challenging to produce robust and defect...... on top of a support membrane. Control membranes, either without aquaporins or with the inactive AqpZ R189A mutant aquaporin served as controls. The separation performance of the membranes was evaluated by cross-flow forward osmosis (FO) and reverse osmosis (RO) tests. In RO the ABM achieved a water...... permeability of ~ 4 L/(m2 h bar) with a NaCl rejection > 97% at an applied hydraulic pressure of 5 bar. The water permeability was ~40% higher compared to a commercial brackish water RO membrane (BW30) and an order of magnitude higher compared to a seawater RO membrane (SW30HR). In FO, the ABMs had > 90...